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Sample records for optoacoustic transducer combining

  1. Three-dimensional modeling of the transducer shape in acoustic resolution optoacoustic microscopy

    Science.gov (United States)

    Deán-Ben, X. Luís.; Estrada, Hector; Kneipp, Moritz; Turner, Jake; Razansky, Daniel

    2014-03-01

    Acoustic resolution optoacoustic microscopy is a powerful modality allowing imaging morphology and function at depths up to a few centimeters in biological tissues. This optoacoustic configuration is based on a spherically-focused ultrasonic transducer raster scanned on an accessible side of the sample to be imaged. Volumetric images can then be formed by stacking up the recorded time-resolved signals at the measured locations. However, the focusing capacity of a spherically-focused transducer depends on its aperture and the acoustic spectrum of the collected signals, which may lead to image artifacts if a simplistic reconstruction approach is employed. In this work, we make use of a model-based reconstruction procedure developed in three dimensions in order to account for the shape of spherically focused transducers in acoustic resolution optoacoustic microscopy set-ups. By discretizing the transducer shape to a set of sub-sensors, the resulting model incorporates the frequency-dependent transducer sensitivity for acquisition of broadband optoacoustic signals. Inversion of the full model incorporating the effects of the transducer shape is then performed iteratively. The obtained results indicate good performance of the method for absorbers of different size emitting optoacoustic waves with different frequency spectra.

  2. Non-contact optoacoustic imaging with focused air-coupled transducers

    Energy Technology Data Exchange (ETDEWEB)

    Deán-Ben, X. Luís [Institute for Biological and Medical Imaging (IBMI), Helmholtz Zentrum München, Neuherberg (Germany); Pang, Genny A.; Razansky, Daniel, E-mail: dr@tum.de [Institute for Biological and Medical Imaging (IBMI), Helmholtz Zentrum München, Neuherberg (Germany); School of Medicine, Technische Universität München (TUM), Munich (Germany); Montero de Espinosa, Francisco [CSIC, Institute of Physics and Communication Technologies, Madrid (Spain)

    2015-08-03

    Non-contact optoacoustic imaging employing raster-scanning of a spherically focused air-coupled ultrasound transducer is showcased herein. Optoacoustic excitation with laser fluence within the maximal permissible human exposure limits in the visible and near-infrared spectra is applied to objects with characteristic dimensions smaller than 1 mm and absorption properties representative of the whole blood at near-infrared wavelengths, and these signals are shown to be detectable without contact to the sample using an air-coupled transducer with reasonable signal averaging. Optoacoustic images of vessel-mimicking tubes embedded in an agar phantom captured with this non-contact sensing technique are also showcased. These initial results indicate that an air-coupled ultrasound detection approach can be suitable for non-contact biomedical imaging with optoacoustics.

  3. Generation of planar blast waves using carbon nanotubes-poly-dimethylsiloxane optoacoustic transducer

    Science.gov (United States)

    Moon, C.; Fan, X.; Ha, K.; Kim, D.

    2017-01-01

    We have generated planar blast waves over the large area using carbon nanotubes(CNT)-poly-dimethylsiloxane(PDMS) optoacoustic transducer. Pulse laser is absorbed by CNT and converted to heat, and the heat is transferred to PDMS inducing its thermal expansion and blast wave generation. To theoretically describe the planar blast wave generation, we build one-dimensional simulation model and find analytical solutions for temperature and pressure distributions. The analytical solution validated by the experimental data sheds light on how to improve the performance of the new transducer. Resonance of acoustic waves inside the transducer is also discussed. The new optoacoustic transducer optimized based on the fundamental understandings will be useful in generating high quality blast waves for research and industrial applications.

  4. Propagation characteristics of shock waves from a plane carbon-nanotube-coated optoacoustic transducer in water

    Science.gov (United States)

    Fan, Xiaofeng; Baek, Yonggeun; Ha, Kanglyeol; Kim, Moojoon; Kim, Jungsoon; Kim, Duckjong; Kang, Hyun Wook; Oh, Junghwan

    2017-07-01

    An optoacoustic transducer made of light-absorbing and elastomeric materials can generate high-pressure wide-band ultrasound waves in water when it is illuminated by a pulse laser. To generate such waves with high efficiency, carbon nanotubes (CNTs) and poly(dimethylsiloxane) (PDMS) are widely used as the light-absorbing and elastomeric materials, respectively. It was previously reported that an optoacoustic concave transducer made of these materials can produce strong shock waves, namely, blast waves, within its focal zone. In this study, we have shown that these waves can also be generated by a plane optoacoustic transducer fabricated by coating CNTs-PDMS on a poly(methyl methacrylate) (PMMA) plate. Some propagation characteristics of the blast wave generated were measured and compared with the calculated results. It was found that the propagation speed and attenuation of the wave are different from those of usual sounds. From the comparison of the measured and the calculated acoustic fields, it is assumed that every point on the transducer surface produces almost the same blast wave.

  5. OPUS: optoacoustic imaging combined with conventional ultrasound for breast cancer detection

    Science.gov (United States)

    Haisch, C.; Zell, K.; Sperl, J. I.; Ketzer, S.; Vogel, M. W.; Menzenbach, P.; Niessner, R.

    2007-07-01

    Besides x-ray imaging, sonography is the most common method for breast cancer screening. The intention of our work is to develop optoacoustical imaging as an add-on to a conventional system. While ultrasound imaging reveals acoustical properties of tissue, optoacoustics generates an image of the distribution of optical absorption. Hence, it can be a valuable addition to sonography, because acoustical properties of different tissues show only a slight variation whereas the optical properties may differ strongly. Additionally, optoacoustics gives access to physiological parameters, like oxygen saturation of blood. For the presented work, we combine a conventional ultrasound system to a 100 Hz laser. The laser system consists of a Nd:YAG-laser at a wavelength of 532 nm with 7 ns pulse duration, coupled to a tunable Optical Parametric Oscillator (OPO) with a tuning rage from 680 nm to 2500 nm. The tunable laser source allows the selection of wavelengths which compromising high spectral information content with high skin transmission. The laser pulse is delivered fiber-optically to the ultrasound transducer and coupled into the acoustical field of view. Homogeneous illumination is crucial in order to achieve unblurred images. Furthermore the maximum allowed pulse intensities in accordance with standards for medical equipment have to be met to achieve a high signal to noise ration. The ultrasound instrument generates the trigger signal which controls the laser pulsing in order to apply ultrasound instrument's imaging procedures without major modifications to generate an optoacoustic image. Detection of the optoacoustic signal as well as of the classical ultrasound signal is carried out by the standard medical ultrasound transducer. The characterization of the system, including quantitative measurements, performed on tissue phantoms, is presented. These phantoms have been specially designed regarding their acoustical as well as their optical properties.

  6. Ionoacoustic tomography of the proton Bragg peak in combination with ultrasound and optoacoustic imaging

    Science.gov (United States)

    Kellnberger, Stephan; Assmann, Walter; Lehrack, Sebastian; Reinhardt, Sabine; Thirolf, Peter; Queirós, Daniel; Sergiadis, George; Dollinger, Günther; Parodi, Katia; Ntziachristos, Vasilis

    2016-07-01

    Ions provide a more advantageous dose distribution than photons for external beam radiotherapy, due to their so-called inverse depth dose deposition and, in particular a characteristic dose maximum at their end-of-range (Bragg peak). The favorable physical interaction properties enable selective treatment of tumors while sparing surrounding healthy tissue, but optimal clinical use requires accurate monitoring of Bragg peak positioning inside tissue. We introduce ionoacoustic tomography based on detection of ion induced ultrasound waves as a technique to provide feedback on the ion beam profile. We demonstrate for 20 MeV protons that ion range imaging is possible with submillimeter accuracy and can be combined with clinical ultrasound and optoacoustic tomography of similar precision. Our results indicate a simple and direct possibility to correlate, in-vivo and in real-time, the conventional ultrasound echo of the tumor region with ionoacoustic tomography. Combined with optoacoustic tomography it offers a well suited pre-clinical imaging system.

  7. Development of combined Opto-Acoustical sensor Modules

    Energy Technology Data Exchange (ETDEWEB)

    Enzenhoefer, A., E-mail: alexander.enzenhoefer@physik.uni-erlangen.de [Friedrich-Alexander-Universitaet Erlangen-Nuernberg, Erlangen Centre for Astroparticle Physics, Erwin-Rommel-Str. 1, D-91058 Erlangen (Germany); Anton, G.; Graf, K.; Hoessl, J.; Katz, U.; Lahmann, R.; Neff, M.; Richardt, C. [Friedrich-Alexander-Universitaet Erlangen-Nuernberg, Erlangen Centre for Astroparticle Physics, Erwin-Rommel-Str. 1, D-91058 Erlangen (Germany)

    2012-01-11

    The faint fluxes of cosmic neutrinos expected at very high energies require large instrumented detector volumes. The necessary volumes in combination with a sufficient shielding against background constitute forbidding and complex environments (e.g. the deep sea) as sites for neutrino telescopes. To withstand these environments and to assure the data quality, the sensors have to be reliable and their operation has to be as simple as possible. A compact sensor module design including all necessary components for data acquisition and module calibration would simplify the detector mechanics and ensures the long term operability of the detector. The compact design discussed here combines optical and acoustical sensors inside one module, therefore reducing electronics and additional external instruments for calibration purposes. In this design the acoustical sensor is primary used for acoustic positioning of the module. The module may also be used for acoustic particle detection and marine science if an appropriate acoustical sensor is chosen. First tests of this design are promising concerning the task of calibration. To expand the field of application also towards acoustic particle detection further improvements concerning electromagnetic shielding and adaptation of the single components are necessary.

  8. Cost-effective optoacoustic system based on the combination of high-power diode lasers

    Science.gov (United States)

    Sánchez, Miguel; Rodríguez, Sergio; Gawali, Sandeep B.; Leggio, Luca; Gallego, Daniel C.; Lamela, Horacio

    2017-03-01

    One of the main issues of the advances in optoacoustic (OA) applications is to reduce the high costs and the big sizes of solid state lasers. High-power diode lasers (HPDLs) have been demonstrated to be a valid alternative reducing enormously the expenses, besides other advantages such as smaller sizes and higher modulation frequencies. However, in some cases it is possible to furtherly reduce their costs. We present a cost-effective OA system based on the combination of several 905-nm HPDLs with direct coupling into a fiber bundle. These HPDLs have an internal pulse driver, based on an n-channel Mosfet and two charging capacitors, which needs an external Mosfet driver circuit and a voltage supply in order to improve the optical pulse shape and energy. We compare the performances and the prices of this OA system with another similar HPDL-based OA system built with commercial elements. Results indicate good OA signal generation ( 15.6 mVpp) with pulse energy of 12.3 μJ and, especially, a cost reduction by a factor of 15 if compared to the other HPDL-based system.

  9. A wideband combined transducer for measuring system in sound tube

    Institute of Scientific and Technical Information of China (English)

    PAN Yaozong; MO Xiping; LIU Yongping; CUI Zheng; ZHANG Tonggen

    2012-01-01

    A wideband transducer for sound tube system is presented, which combines longitudinal transducer and Class IV flextensional transducer to improve the performance at low frequency and broaden the working band. The equivalent circuit is obtained and used to analyze the coupling mechanism between longitudinal transducer and flextensional transducer. A prototype of the transducer is developed after optimizing the electro-acoustic performances by Finite Element Method. The standing wave in the sound tube stimulated by this transducer has been studied and the sound absorbing coefficients of two acoustic materials samples are measured using this sound tube, which shows that the transducer can meet the requirements of acoustic material measurement with the working band ranging from 1.4 kHz to 23 kHz.

  10. High-Resolution Multispectral Optoacoustic Tomography of the Vascularization and Constitutive Hypoxemia of Cancerous Tumors

    Directory of Open Access Journals (Sweden)

    Andrei Chekkoury

    2016-08-01

    Full Text Available Diversity of the design and alignment of illumination and ultrasonic transducers empower the fine scalability and versatility of optoacoustic imaging. In this study, we implement an innovative high-resolution optoacoustic mesoscopy for imaging the vasculature and tissue oxygenation within subcutaneous and orthotopic cancerous implants of mice in vivo through acquisition of tomographic projections over 180° at a central frequency of 24 MHz. High-resolution volumetric imaging was combined with multispectral functional measurements to resolve the exquisite inner structure and vascularization of the entire tumor mass using endogenous and exogenous optoacoustic contrast. Evidence is presented for constitutive hypoxemia within the carcinogenic tissue through analysis of the hemoglobin absorption spectra and distribution. Morphometric readouts obtained with optoacoustic mesoscopy have been verified with high-resolution ultramicroscopic studies. The findings described herein greatly extend the applications of optoacoustic mesoscopy toward structural and multispectral functional measurements of the vascularization and hemodynamics within solid tumors in vivo and are of major relevance to basic and preclinical oncological studies in small animal models.

  11. First practical experiences with the optoacoustic/ultrasound system OPUS

    Science.gov (United States)

    Zell, Karin; Vogel, Mika W.; Menzenbach, Peter; Niessner, Reinhard; Haisch, Christoph

    2008-02-01

    The OPUS (OPtoacoustic UltraSound) system combines a conventional ultrasound (US) system with a specially designed OPO (Optical Parametrical Oscillator) laser system to generate and detect optoacoustical (OA) signals at multiple wavelengths. The intention of this combination was to demonstrate that a conventional ultrasound system can be transformed into an optoacoustic module without major modifications. To offer operational ease of use similar to those of the conventional US instrumentation, i.e. slow moving of the US transducer over the examined tissue area, a high repetition rate of the laser is required. A repetition rate of 100 Hz of the laser system enables a fast image frame rate. Different approaches for the presentation of the two types of images to the operator are compared. For an optimum applicability of the system we found it essential to provide both, the well-known US image and the OA image of the same tissue section to the user. The operator has now the possibility to overlay both images on one screen and thus to extract the desired information from each imaging mode.

  12. Monitoring of tissue coagulation during thermotherapy using optoacoustic technique

    Energy Technology Data Exchange (ETDEWEB)

    Larin, Kirill V [Center for Biomedical Engineering, University of Texas Medical Branch, Galveston, TX 77555 (United States); Larina, Irina V [Center for Biomedical Engineering, University of Texas Medical Branch, Galveston, TX 77555 (United States); Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, TX 77555 (United States); Esenaliev, Rinat O [Center for Biomedical Engineering, University of Texas Medical Branch, Galveston, TX 77555 (United States); Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, TX 77555 (United States); Department of Anesthesiology, University of Texas Medical Branch, Galveston, TX 77555 (United States)

    2005-08-07

    In this paper we have applied the laser optoacoustic technique for real time noninvasive monitoring of thermal damage in tissues. Changes in tissue optical properties during coagulation were detected by measuring and analysing amplitude and temporal characteristics of optoacoustic signals. Coagulation of liver, myocardium and prostate was induced by interstitial continuous wave Nd : YAG laser irradiation of the samples or by conductive heating. Real time detection of thermally-induced changes in optical properties was performed with sensitive wide-band acoustic transducers. Combination of optoacoustic and diffuse reflectance technique was applied for determination of tissue optical properties: effective attenuation, total diffuse reflectance, reduced scattering coefficient and absorption coefficient. The optical properties did not change up to temperature of coagulation (about 53{sup 0}C) and sharply increased during heating up to 70{sup 0}C. Monitoring of the expansion of interstitial coagulation front within freshly excised canine tissues was performed in real time with spatial resolution of about 0.6 mm. The results of our study suggest that this technique can potentially be used for real time precise thermotherapy of malignant and benign lesions at depths of the order of the centimetre.

  13. Quantitative analysis with the optoacoustic/ultrasound system OPUS

    Science.gov (United States)

    Haisch, Christoph; Zell, Karin; Sperl, Jonathan; Vogel, Mika W.; Niessner, Reinhard

    2009-02-01

    The OPUS (Optoacoustic plus Ultrasound) system is a combination of a medical ultrasound scanner with a highrepetition rate, wavelength-tunable laser system and a suitable triggering interface to synchronize the laser and the ultrasound system. The pulsed laser generates an optoacoustic (OA), or photoacoustic (PA), signal which is detected by the ultrasound system. Alternatively, imaging in conventional ultrasound mode can be performed. Both imaging modes can be superimposed. The laser light is coupled into the tissue laterally, parallel to the ultrasound transducer, which does not require for any major modification to the transducer or the ultrasound beam forming. This was a basic requirement on the instrument, as the intention of the project was to establish the optoacoustic imaging modality as add-on to a conventional standard ultrasound instrument. We believe that this approach may foster the introduction of OA imaging as routine tool in medical diagnosis. Another key aspect of the project was to exploit the capabilities of OA imaging for quantitative analysis. The intention of the presented work is to summarize all steps necessary to extract the significant information from the PA raw data, which are required for the quantification of local absorber distributions. We show results of spatially resolved absorption measurements in scattering samples and a comparison of four different image reconstruction algorithms, regarding their influence on lateral resolution as well as on the signal to noise ratio for different sample depths and absorption values. The reconstruction algorithms are based on Fourier transformation, on a generalized 2D Hough transformation, on circular back-projection and the classical delay-and-sum approach which is implemented in most ultrasound scanners. Furthermore, we discuss the influence of a newly developed laser source, combining diode and flash lamp pumping. Compared to all-flash-lamp pumped systems it features a significantly higher

  14. Combined Opto-Acoustical Sensor Modules for KM3NeT

    CERN Document Server

    Enzenhöfer, Alexander

    2014-01-01

    KM3NeT is a future multi-cubic-kilometre water Cherenkov neutrino telescope currently entering a first construction phase. It will be located in the Mediterranean Sea and comprise about 600 vertical structures called detection units. Each of these detection units has a length of several hundred metres and is anchored to the sea bed on one side and held taut by a buoy on the other side. The detection units are thus subject to permanent movement due to sea currents. Modules holding photosensors and additional equipment are equally distributed along the detection units. The relative positions of the photosensors has to be known with an uncertainty below $20\\,$cm in order to achieve the necessary precision for neutrino astronomy. These positions can be determined with an acoustic positioning system: dedicated acoustic emitters located at known positions and acoustic receivers along each detection unit. This article describes the approach to combine an acoustic receiver with the photosensors inside one detection m...

  15. Language Model Combination and Adaptation Using Weighted Finite State Transducers

    Science.gov (United States)

    Liu, X.; Gales, M. J. F.; Hieronymus, J. L.; Woodland, P. C.

    2010-01-01

    In speech recognition systems language model (LMs) are often constructed by training and combining multiple n-gram models. They can be either used to represent different genres or tasks found in diverse text sources, or capture stochastic properties of different linguistic symbol sequences, for example, syllables and words. Unsupervised LM adaption may also be used to further improve robustness to varying styles or tasks. When using these techniques, extensive software changes are often required. In this paper an alternative and more general approach based on weighted finite state transducers (WFSTs) is investigated for LM combination and adaptation. As it is entirely based on well-defined WFST operations, minimum change to decoding tools is needed. A wide range of LM combination configurations can be flexibly supported. An efficient on-the-fly WFST decoding algorithm is also proposed. Significant error rate gains of 7.3% relative were obtained on a state-of-the-art broadcast audio recognition task using a history dependently adapted multi-level LM modelling both syllable and word sequences

  16. Transmission (forward) mode, transcranial, noninvasive optoacoustic measurements for brain monitoring, imaging, and sensing

    Science.gov (United States)

    Petrov, Irene Y.; Petrov, Yuriy; Prough, Donald S.; Richardson, C. Joan; Fonseca, Rafael A.; Robertson, Claudia S.; Asokan, C. Vasantha; Agbor, Adaeze; Esenaliev, Rinat O.

    2016-03-01

    We proposed to use transmission (forward) mode for cerebral, noninvasive, transcranial optoacoustic monitoring, imaging, and sensing in humans. In the transmission mode, the irradiation of the tissue of interest and detection of optoacoustic signals are performed from opposite hemispheres, while in the reflection (backward) mode the irradiation of the tissue of interest and detection of optoacoustic signals are performed from the same hemisphere. Recently, we developed new, transmission-mode optoacoustic probes for patients with traumatic brain injury (TBI) and for neonatal patients. The transmission mode probes have two major parts: a fiber-optic delivery system and an acoustic transducer (sensor). To obtain optoacoustic signals in the transmission mode, in this study we placed the sensor on the forehead, while light was delivered to the opposite side of the head. Using a medical grade, multi-wavelength, OPObased optoacoustic system tunable in the near infrared spectral range (680-950 nm) and a novel, compact, fiber-coupled, multi-wavelength, pulsed laser diode-based system, we recorded optoacoustic signals generated in the posterior part of the head of adults with TBI and neonates. The optoacoustic signals had two distinct peaks: the first peak from the intracranial space and the second peak from the scalp. The first peak generated by cerebral blood was used to measure cerebral blood oxygenation. Moreover, the transmission mode measurements provided detection of intracranial hematomas in the TBI patients. The obtained results suggest that the transmission mode can be used for optoacoustic brain imaging, tomography, and mapping in humans.

  17. Dynamic particle enhancement in limited-view optoacoustic tomography

    CERN Document Server

    Dean-Ben, X L; Razansky, D

    2015-01-01

    Limited-view artefacts are commonly present in optoacoustic tomography images, mainly due to practical geometrical and physical constraints imposed by the imaging systems as well as limited light penetration into large optically opaque samples. Herein, a new approach termed dynamic particle-enhanced optoacoustic tomography (DPOT) is proposed for improving image contrast and visibility of optoacoustic images under limited-view scenarios. The method is based on the non- linear combination of a temporal sequence of tomographic reconstructions representing sparsely distributed moving particles. We demonstrate experimental performance by dynamically imaging the flow of suspended microspheres in three dimensions, which shows promise for DPOT applicability in angiographic imaging in living organisms.

  18. Mesoscopic and Macroscopic Optoacoustic Imaging of Cancer

    NARCIS (Netherlands)

    Taruttis, Adrian; van Dam, Gooitzen M.; Ntziachristos, Vasilis

    2015-01-01

    Optoacoustic imaging combines the rich contrast of optical methods with the resolution of ultrasound imaging. It can therefore deliver optical visualization of cancer far deeper in tissue than optical microscopy and other conventional optical imaging methods. Technological progress and novel contras

  19. Transducer combination for high-quality ultrasound tomography based on speed of sound imaging

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Young Hun; Park, Kwan Kyu [Dept. of Mechanical Engineering, Hanyang University, Seoul (Korea, Republic of)

    2016-02-15

    The type of ultrasound transducer used influences the quality of a reconstructed ultrasound image. This study analyzed the effect of transducer type on ultrasound computed tomography (UCT) image quality. The UCT was modeled in an ultrasound simulator by using a 5 cm anatomy model and a ring-shape 5 MHz 128 transducer array, which considered attenuation, refraction, and reflection. Speed-of-sound images were reconstructed by the Radon transform as the UCT image modality. Acoustic impedance images were also reconstructed by the delayand-sum (DAS) method, which considered the speed of sound information. To determine the optimal combination of transducers in observation, point-source, flat, and focused transducers were tested in combination as trasmitters and receivers; UCT images were constructed from each combination. The combination of point-source/flat transducer as transmitting and receiving devices presented the best reconstructed image quality. In UCT implementation, the combination of a flat transducer for transmitting and a point transducer for receiving permitted acceptable image quality.

  20. Multilayer piezoelectric transducer models combined with Field II

    DEFF Research Database (Denmark)

    Bæk, David; Willatzen, Morten; Jensen, Jørgen Arendt

    2012-01-01

    with a polymer ring, and submerged into water. The transducer models are developed to account for any external electrical loading impedance in the driving circuit. The models are adapted to calculate the surface acceleration needed by the Field II software in predicting pressure pulses at any location in front...

  1. Multifunctional Magnetic Gd(3+) -Based Coordination Polymer Nanoparticles: Combination of Magnetic Resonance and Multispectral Optoacoustic Detections for Tumor-Targeted Imaging in vivo.

    Science.gov (United States)

    An, Qiao; Liu, Jing; Yu, Meng; Wan, Jiaxun; Li, Dian; Wang, Changchun; Chen, Chunying; Guo, Jia

    2015-11-11

    To overcome traditional barriers in optical imaging and microscopy, optoacoustic-imaging has been changed to combine the accuracy of spectroscopy with the depth resolution of ultrasound, achieving a novel modality with powerful in vivo imaging. However, magnetic resonance imaging provides better spatial and anatomical resolution. Thus, a single hybrid nanoprobe that allows for simultaneous multimodal imaging is significant not only for cutting edge research in imaging science, but also for accurate clinical diagnosis. A core-shell-structured coordination polymer composite microsphere has been designed for in vivo multimodality imaging. It consists of a Fe3 O4 nanocluster core, a carbon sandwiched layer, and a carbocyanine-Gd(III) (Cy-Gd(III) ) coordination polymer outer shell (Fe3 O4 @C@Cy-Gd(III) ). Folic acid-conjugated poly(ethylene glycol) chains are embedded within the coordination polymer shell to achieve extended circulation and targeted delivery of probe particles in vivo. Control of Fe3 O4 core grain sizes results in optimal r2 relaxivity (224.5 × 10(-3) m(-1) s(-1) ) for T2 -weighted magnetic resonance imaging. Cy-Gd(III) coordination polymers are also regulated to obtain a maximum 25.1% of Cy ligands and 5.2% of Gd(III) ions for near-infrared fluorescence and T1 -weighted magnetic resonance imaging, respectively. The results demonstrate their impressive abilities for targeted, multimodal, and reliable imaging.

  2. Clinical feasibility study of combined opto-acoustic and ultrasonic imaging modality providing coregistered functional and anatomical maps of breast tumors

    Science.gov (United States)

    Zalev, Jason; Clingman, Bryan; Smith, Remie J.; Herzog, Don; Miller, Tom; Stavros, A. Thomas; Ermilov, Sergey; Conjusteau, André; Tsyboulski, Dmitri; Oraevsky, Alexander A.; Kist, Kenneth; Dornbluth, N. C.; Otto, Pamela

    2013-03-01

    We report on findings from the clinical feasibility study of the ImagioTM. Breast Imaging System, which acquires two-dimensional opto-acoustic (OA) images co-registered with conventional ultrasound using a specialized duplex hand-held probe. Dual-wavelength opto-acoustic technology is used to generate parametric maps based upon total hemoglobin and its oxygen saturation in breast tissues. This may provide functional diagnostic information pertaining to tumor metabolism and microvasculature, which is complementary to morphological information obtained with conventional gray-scale ultrasound. We present co-registered opto-acoustic and ultrasonic images of malignant and benign tumors from a recent clinical feasibility study. The clinical results illustrate that the technology may have the capability to improve the efficacy of breast tumor diagnosis. In doing so, it may have the potential to reduce biopsies and to characterize cancers that were not seen well with conventional gray-scale ultrasound alone.

  3. High-resolution ultrasound imaging and noninvasive optoacoustic monitoring of blood variables in peripheral blood vessels

    Science.gov (United States)

    Petrov, Irene Y.; Petrov, Yuriy; Prough, Donald S.; Esenaliev, Rinat O.

    2011-03-01

    Ultrasound imaging is being widely used in clinics to obtain diagnostic information non-invasively and in real time. A high-resolution ultrasound imaging platform, Vevo (VisualSonics, Inc.) provides in vivo, real-time images with exceptional resolution (up to 30 microns) using high-frequency transducers (up to 80 MHz). Recently, we built optoacoustic systems for probing radial artery and peripheral veins that can be used for noninvasive monitoring of total hemoglobin concentration, oxyhemoglobin saturation, and concentration of important endogenous and exogenous chromophores (such as ICG). In this work we used the high-resolution ultrasound imaging system Vevo 770 for visualization of the radial artery and peripheral veins and acquired corresponding optoacoustic signals from them using the optoacoustic systems. Analysis of the optoacoustic data with a specially developed algorithm allowed for measurement of blood oxygenation in the blood vessels as well as for continuous, real-time monitoring of arterial and venous blood oxygenation. Our results indicate that: 1) the optoacoustic technique (unlike pure optical approaches and other noninvasive techniques) is capable of accurate peripheral venous oxygenation measurement; and 2) peripheral venous oxygenation is dependent on skin temperature and local hemodynamics. Moreover, we performed for the first time (to the best of our knowledge) a comparative study of optoacoustic arterial oximetry and a standard pulse oximeter in humans and demonstrated superior performance of the optoacoustic arterial oximeter, in particular at low blood flow.

  4. Wideband radial power combiner/divider fed by a mode transducer

    Science.gov (United States)

    Epp, Larry W. (Inventor); Hoppe, Daniel J. (Inventor); Kelley, Daniel (Inventor); Khan, Abdur R. (Inventor)

    2008-01-01

    A radial power combiner/divider capable of a higher order (for example, N=24) of power combining/dividing and a 15% bandwidth (31 to 36 GHz). The radial power combiner/divider generally comprises an axially-oriented mode transducer coupled to a radial base. The mode transducer transduces circular TE01 waveguide into rectangular TE10 waveguide, and the unique radial base combines/divides a plurality of peripheral rectangular waveguide ports into a single circular TE01 waveguide end of the transducer. The radial base incorporates full-height waveguides that are stepped down to reduced-height waveguides to form a stepped-impedance configuration, thereby reducing the height of the waveguides inside the base and increasing the order N of combining/dividing. The reduced-height waveguides in the base converge radially to a matching post at the bottom center of the radial base which matches the reduced height rectangular waveguides into the circular waveguide that feeds the mode transducer.

  5. Optoacoustic Microscopy for Investigation of Material Nanostructures-Embracing the Ultrasmall, Ultrafast, and the Invisible

    Energy Technology Data Exchange (ETDEWEB)

    Nurmikko, Arto; Humphrey, Maris

    2014-07-10

    The goal of this grant was the development of a new type of scanning acoustic microscope for nanometer resolution ultrasound imaging, based on ultrafast optoacoustics (>GHz). In the microscope, subpicosecond laser pulses was used to generate and detect very high frequency ultrasound with nanometer wavelengths. We report here on the outcome of the 3-year DOE/BES grant which involved the design, multifaceted construction, and proof-of-concept demonstration of an instrument that can be used for quantitative imaging of nanoscale material features – including features that may be buried so as to be inaccessible to conventional lightwave or electron microscopies. The research program has produced a prototype scanning optoacoustic microscope which, in combination with advanced computational modeling, is a system-level new technology (two patents issues) which offer novel means for precision metrology of material nanostructures, particularly those that are of contemporary interest to the frontline micro- and optoelectronics device industry. For accomplishing the ambitious technical goals, the research roadmap was designed and implemented in two phases. In Phase I, we constructed a “non-focusing” optoacoustic microscope instrument (“POAM”), with nanometer vertical (z-) resolution, while limited to approximately 10 micrometer scale lateral recolution. The Phase I version of the instrument which was guided by extensive acoustic and optical numerical modeling of the basic underlying acoustic and optical physics, featured nanometer scale close loop positioning between the optoacoustic transducer element and a nanostructured material sample under investigation. In phase II, we implemented and demonstrated a scanning version of the instrument (“SOAM”) where incident acoustic energy is focused, and scanned on lateral (x-y) spatial scale in the 100 nm range as per the goals of the project. In so doing we developed advanced numerical simulations to provide

  6. In vivo testing of laser optoacoustic system for image-guided biopsy of prostate

    Science.gov (United States)

    Oraevsky, Alexander; Ermilov, Sergey; Mehta, Ketan; Miller, Tom; Bell, Brent; Orihuela, Eduardo; Motamedi, Massoud

    2006-02-01

    We have developed and used a laser optoacoustic imaging system with transrectal probe (LOIS-P) for detection of mechanical lesions in canine prostates in vivo. LOIS images have been acquired with a 128-channel transrectal probe and a 32-channel data acquisition system. Optoacoustic images showed a strong contrast enhancement for a blood containing lesion, when compared with ultrasound images. Our studies demonstrated that sufficient optoacoustic contrast exists between blood containing lesion and prostate tissue, although the lesion has been undetectable with ultrasound. The imaging results have been compared with visual examination of surgically excised prostates. Although axial resolution of the wide-band transducers employed in the transrectal probe provides good axial resolution of 0.5 mm, the convex arc geometry of the this array of transducers provides lateral resolution degrading with depth in tissue. A two step algorithm has been developed to improve the lateral resolution of deeply located objects. This algorithm employs optoacoustic image reconstruction based on radial back-projection to determine location and shape of the target object, then a procedure, we call Maximum Angular Amplitude Probability (MAAP), to determine true brightness of the object and simultaneously remove arc-shaped artifacts associated with radial back-projection. A laser optoacoustic imaging system (LOIS-P) with transrectal probe operating in backward detection mode empowered with the new image reconstruction algorithm seems promising as a modality for detection of prostate cancer and guiding prostate biopsy.

  7. Echographic detectability of optoacoustic signals from low-concentration PEG-coated gold nanorods

    Directory of Open Access Journals (Sweden)

    Conversano F

    2012-08-01

    Full Text Available Francesco Conversano,1 Giulia Soloperto,1 Antonio Greco,1 Andrea Ragusa,1,2 Ernesto Casciaro,1 Fernanda Chiriacò,1 Christian Demitri,3 Giuseppe Gigli,2–5 Alfonso Maffezzoli,3 Sergio Casciaro11National Research Council, Institute of Clinical Physiology, Lecce, Italy; 2National Nanotechnology Laboratory of CNR-NANO, Lecce, Italy; 3University of Salento, Department of Engineering for Innovation, Lecce, Italy; 4Italian Institute of Technology – Center for Biomolecular Nanotechnology (CBN-IIT, Arnesano, Italy; 5University of Salento, Department of Mathematics and Physics ‘Ennio De Giorgi’, Lecce, ItalyPurpose: To evaluate the diagnostic performance of gold nanorod (GNR-enhanced optoacoustic imaging employing a conventional echographic device and to determine the most effective operative configuration in order to assure optoacoustic effectiveness, nanoparticle stability, and imaging procedure safety.Methods: The most suitable laser parameters were experimentally determined in order to assure nanoparticle stability during the optoacoustic imaging procedures. The selected configuration was then applied to a novel tissue-mimicking phantom, in which GNR solutions covering a wide range of low concentrations (25–200 pM and different sample volumes (50–200 µL were exposed to pulsed laser irradiation. GNR-emitted optoacoustic signals were acquired either by a couple of single-element ultrasound probes or by an echographic transducer. Off-line analysis included: (a quantitative evaluation of the relationships between GNR concentration, sample volume, phantom geometry, and amplitude of optoacoustic signals propagating along different directions; (b echographic detection of “optoacoustic spots,” analyzing their intensity, spatial distribution, and clinical exploitability. MTT measurements performed on two different cell lines were also used to quantify biocompatibility of the synthesized GNRs in the adopted doses.Results: Laser irradiation at

  8. Optoacoustic angiography of peripheral vasculature

    Science.gov (United States)

    Ermilov, Sergey; Su, Richard; Zamora, Mario; Hernandez, Travis; Nadvoretsky, Vyacheslav; Oraevsky, Alexander

    2012-02-01

    We developed a new optoacoustic microangiography system (OmAS) intended for in-vivo vascular imaging of a human finger. The system employs an arc-shaped acoustic array that is rotated 360 degrees around the finger providing optoacoustic data necessary for tomographic reconstruction of the three-dimensional images of a finger. A near-infrared Q-switched laser is used to generate optoacoustic signals with increased contrast of blood vessels. The laser is coupled through two randomized fiberoptic bundles oriented in orthogonal optoacoustic mode. To demonstrate OmAS capabilities, we present a time-series of optoacoustic images of a human finger taken after the hypothermia stress test. The images show a detailed vascular anatomy of a finger down to the capillary level. A series of quick 30s scans allowed us to visualize the thermoregulatory response within the studied finger as it was manifested via vasomotor activity during the hypothermia recovery. We propose that the developed system can be used for diagnostics of various medical conditions that are manifested in change of the peripheral (finger) blood flow. Examples of the medical conditions that could be diagnosed and staged using the OmAS include the peripheral arterial disease (PAD), thrombosis, frostbite, and traumas.

  9. Optoacoustic monitoring of cutting efficiency and thermal damage during laser ablation.

    Science.gov (United States)

    Bay, Erwin; Douplik, Alexandre; Razansky, Daniel

    2014-05-01

    Successful laser surgery is characterized by a precise cut and effective hemostasis with minimal collateral thermal damage to the adjacent tissues. Consequently, the surgeon needs to control several parameters, such as power, pulse repetition rate, and velocity of movements. In this study we propose utilizing optoacoustics for providing the necessary real-time feedback of cutting efficiency and collateral thermal damage. Laser ablation was performed on a bovine meat slab using a Q-switched Nd-YAG laser (532 nm, 4 kHz, 18 W). Due to the short pulse duration of 7.6 ns, the same laser has also been used for generation of optoacoustic signals. Both the shockwaves, generated due to tissue removal, as well as the normal optoacoustic responses from the surrounding tissue were detected using a single broadband piezoelectric transducer. It has been observed that the rapid reduction in the shockwave amplitude occurs as more material is being removed, indicating decrease in cutting efficiency, whereas gradual decrease in the optoacoustic signal likely corresponds to coagulation around the ablation crater. Further heating of the surrounding tissue leads to carbonization accompanied by a significant shift in the optoacoustic spectra. Our results hold promise for real-time monitoring of cutting efficiency and collateral thermal damage during laser surgery. In practice, this could eventually facilitate development of automatic cut-off mechanisms that will guarantee an optimal tradeoff between cutting and heating while avoiding severe thermal damage to the surrounding tissues.

  10. Oil-water two-phase flow measurement with combined ultrasonic transducer and electrical sensors

    Science.gov (United States)

    Tan, Chao; Yuan, Ye; Dong, Xiaoxiao; Dong, Feng

    2016-12-01

    A combination of ultrasonic transducers operated in continuous mode and a conductance/capacitance sensor (UTCC) is proposed to estimate the individual flow velocities in oil-water two-phase flows. Based on the Doppler effect, the transducers measure the flow velocity and the conductance/capacitance sensor estimates the phase fraction. A set of theoretical correlations based on the boundary layer models of the oil-water two-phase flow was proposed to describe the velocity profile. The models were separately established for the dispersion flow and the separate flow. The superficial flow velocity of each phase is calculated with the velocity measured in the sampling volume of the ultrasonic transducer with the phase fraction through the velocity profile models. The measuring system of the UTCC was designed and experimentally verified on a multiphase flow loop. The results indicate that the proposed system and correlations estimate the overall flow velocity at an uncertainty of U J   =  0.038 m s-1, and the water superficial velocity at U Jw   =  0.026 m s-1, and oil superficial velocity at U Jo   =  0.034 m s-1. The influencing factors of uncertainty were analyzed.

  11. Optoacoustic sensing for target detection inside cylindrical catheters

    Science.gov (United States)

    Tavakoli, Behnoosh; Guo, Xiaoyu; Taylor, Russell H.; Kang, Jin U.; Boctor, Emad M.

    2014-03-01

    Optoacoustic sensing is a hybrid technique that combines the advantages of high sensing depth of ultrasound with contrast of optical absorption. In this study a miniature optoacoustic probe that can characterize the target properties located at the distal end of a catheter is investigated. The probe includes an optical fiber to illuminate the target with the pulsed laser light and a hydrophone to detect the generated optoacoustic signal. The probe is designed for the forwardsensing and therefore the acoustic signal propagates along the tube before being detected. Due to the circular geometry, the waves inside the tube are highly complex. A three dimensional numerical simulation is performed to model the optoacoustic wave generation and propagation inside the water filled cylindrical tubes. The effect of the boundary condition, tube diameter and target size on the detected signal is systematically evaluated. A prototype of the probe is made and tested for detecting an absorbing target inside a 2mm diameter tube submerged in water. The preliminary experimental results corresponding to the simulation is acquired. Although many different medical applications for this miniature probe may exist, our main focus is on detecting the occlusion inside the ventricular shunts. These catheters are used to divert the excess cerebrospinal fluid to the absorption site and regulate inter cranial pressure of hydrocephalous patients. Unfortunately the malfunction rate of these catheters due to blockage is very high. This sensing tool could locate the occluding tissue non-invasively and can potentially characterize the occlusion composites by scanning at different wavelengths of the light.

  12. Model-based optoacoustic inversion with arbitrary-shape detectors.

    Science.gov (United States)

    Rosenthal, Amir; Ntziachristos, Vasilis; Razansky, Daniel

    2011-07-01

    Optoacoustic imaging enables mapping the optical absorption of biological tissue using optical excitation and acoustic detection. Although most image-reconstruction algorithms are based on the assumption of a detector with an isotropic sensitivity, the geometry of the detector often leads to a response with spatially dependent magnitude and bandwidth. This effect may lead to attenuation or distortion in the recorded signal and, consequently, in the reconstructed image. Herein, an accurate numerical method for simulating the spatially dependent response of an arbitrary-shape acoustic transducer is presented. The method is based on an analytical solution obtained for a two-dimensional line detector. The calculated response is incorporated in the forward model matrix of an optoacoustic imaging setup using temporal convolution, and image reconstruction is performed by inverting the matrix relation. The method was numerically and experimentally demonstrated in two dimensions for both flat and focused transducers and compared to the spatial-convolution method. In forward simulations, the developed method did not suffer from the numerical errors exhibited by the spatial-convolution method. In reconstruction simulations and experiments, the use of both temporal-convolution and spatial-convolution methods lead to an enhancement in resolution compared to a reconstruction with a point detector model. However, because of its higher modeling accuracy, the temporal-convolution method achieved a noise figure approximated three times lower than the spatial-convolution method. The demonstrated performance of the spatial-convolution method shows it is a powerful tool for reducing reconstruction artifacts originating from the detector finite size and improving the quality of optoacoustic reconstructions. Furthermore, the method may be used for assessing new system designs. Specifically, detectors with nonstandard shapes may be investigated.

  13. Gigahertz optoacoustic imaging for cellular imaging

    Science.gov (United States)

    Rui, Min; Narashimhan, Sankar; Bost, Wolfgang; Stracke, Frank; Weiss, Eike; Lemor, Robert; Kolios, Michael C.

    2010-02-01

    Photoacoustic imaging exploits contrast mechanisms that depend on optical and thermomechanical properties of optical absorbers. The photoacoustic signal bandwidth is dictated by the absorber size and the laser pulse width. In this work we demonstrate that photoacoustic signals can be detected from micron and sub-micron particles. We anticipate applications to include cellular imaging with nanometer sized contrast agents such as gold nanoshells, nanorods, and nanocages. An existing acoustic microscopy system was used (the SASAM 1000, kibero GmbH). This platform is developed on an Olympus IX81 optical microscope with a rotating column that has an optical condenser for transmission optical microscopy and an acoustic module for the acoustic microscopy. The adapted optoacoustic module consists of a Qswitched Nd:YAG solid-state-laser (Teem Photonics, France) generating sub-nanosecond pulses. Scans were acquired of microparticles (1 μm black Toner particles) and cells. The confocal arrangement allowed high signal to noise ratio photoacoustic signals (>30 dB) to be detected at approximately 400 MHz. The particles of various sizes produced signals of different frequency content. In imaging mode, the full width half maximum (FWHM) was measured to be 3.6 μm for the 400 MHz transducer which is in general agreement theory for a 0.3 NA objective (4.3μm). Moreover, images are generated from single melanoma cells, generated by the endogenous contrast from the intracellular melanin.

  14. Multimodal optoacoustic and multiphoton microscopy of human carotid atheroma

    Directory of Open Access Journals (Sweden)

    Markus Seeger

    2016-09-01

    Full Text Available Carotid artery atherosclerosis is a main cause of stroke. Understanding atherosclerosis biology is critical in the development of targeted prevention and treatment strategies. Consequently, there is demand for advanced tools investigating atheroma pathology. We consider hybrid optoacoustic and multiphoton microscopy for the integrated and complementary interrogation of plaque tissue constituents and their mutual interactions. Herein, we visualize human carotid plaque using a hybrid multimodal imaging system that combines optical resolution optoacoustic (photoacoustic microscopy, second and third harmonic generation microscopy, and two-photon excitation fluorescence microscopy. Our data suggest more comprehensive insights in the pathophysiology of atheroma formation and destabilization, by enabling congruent visualization of structural and biological features critical for the atherosclerotic process and its acute complications, such as red blood cells and collagen.

  15. New improvement of the combined optical fiber transducer for landslide monitoring

    Science.gov (United States)

    Zhu, Z.-W.; Yuan, Q.-Y.; Liu, D.-Y.; Liu, B.; Liu, J.-C.; Luo, H.

    2014-08-01

    Landslide monitoring is important in predicting the behavior of landslides, thereby ensuring environmental, life, and property safety. On the basis of our previous studies, we conducted the double shear test by using a third-generation optical fiber transducer that uses expandable polystyrene (EPS) as base material. However, the third-generation transducer has poor performance when cohesive force is present between the grout and capillary stainless steel pipe of the transducer. Thus, the fourth-generation optical fiber transducer was invented. Similar to the third-generation transducer, the fourth-generation transducer also used EPS as its base material. Single shear test was conducted on the fourth-generation transducer after being grouted with cement mortar (1 : 1 mix ratio). The micro-bend loss mechanism of the optical fiber was considered, and the optical time domain reflectometry instrument was used. The fact that the loss sequence of optical fibers subjected to loading is different at various locations is found. The relationship of the loading-point displacement vs. optical fiber sliding distance and optical loss were measured. Results show that the maximum initial measurement precision of the newly proposed device is 1 mm, the corresponding sliding distance is 21 mm, and the dynamic range is 0-20 mm. The fourth-generation transducer can measure the movement direction of loadings, thus making this transducer applicable for landslide monitoring.

  16. Microstructured polymer optical fibre sensors for opto-acoustic endoscopy

    Science.gov (United States)

    Broadway, Christian; Gallego, Daniel; Pospori, Andreas; Zubel, Michal; Webb, David J.; Sugden, Kate; Carpintero, Guillermo; Lamela, Horacio

    2016-04-01

    Opto-acoustic imaging is a growing field of research in recent years, providing functional imaging of physiological biomarkers, such as the oxygenation of haemoglobin. Piezo electric transducers are the industry standard detector for ultrasonics, but their limited bandwidth, susceptibility to electromagnetic interference and their inversely proportional sensitivity to size all affect the detector performance. Sensors based on polymer optical fibres (POF) are immune to electromagnetic interference, have lower acoustic impedance and a reduced Young's Modulus compared to silica fibres. Furthermore, POF enables the possibility of a wideband sensor and a size appropriate to endoscopy. Micro-structured POF (mPOF) used in an interferometric detector has been shown to be an order of magnitude more sensitive than silica fibre at 1 MHz and 3 times more sensitive at 10 MHz. We present the first opto-acoustic measurements obtained using a 4.7mm PMMA mPOF Bragg grating with a fibre diameter of 130 μm and present the lateral directivity pattern of a PMMA mPOF FBG ultrasound sensor over a frequency range of 1-50 MHz. We discuss the impact of the pattern with respect to the targeted application and draw conclusions on how to mitigate the problems encountered.

  17. Actuatable capacitive transducer for quantitative nanoindentation combined with transmission electron microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Warren, Oden L; Asif, Syed Amanula Syed; Cyrankowski, Edward; Kounev, Kalin

    2013-06-04

    An actuatable capacitive transducer including a transducer body, a first capacitor including a displaceable electrode and electrically configured as an electrostatic actuator, and a second capacitor including a displaceable electrode and electrically configured as a capacitive displacement sensor, wherein the second capacitor comprises a multi-plate capacitor. The actuatable capacitive transducer further includes a coupling shaft configured to mechanically couple the displaceable electrode of the first capacitor to the displaceable electrode of the second capacitor to form a displaceable electrode unit which is displaceable relative to the transducer body, and an electrically-conductive indenter mechanically coupled to the coupling shaft so as to be displaceable in unison with the displaceable electrode unit.

  18. Actuatable capacitive transducer for quantitative nanoindentation combined with transmission electron microscopy

    Science.gov (United States)

    Warren, Oden L.; Asif, S. A. Syed; Cyrankowski, Edward; Kounev, Kalin

    2010-09-21

    An actuatable capacitive transducer including a transducer body, a first capacitor including a displaceable electrode and electrically configured as an electrostatic actuator, and a second capacitor including a displaceable electrode and electrically configured as a capacitive displacement sensor, wherein the second capacitor comprises a multi-plate capacitor. The actuatable capacitive transducer further includes a coupling shaft configured to mechanically couple the displaceable electrode of the first capacitor to the displaceable electrode of the second capacitor to form a displaceable electrode unit which is displaceable relative to the transducer body, and an electrically-conductive indenter mechanically coupled to the coupling shaft so as to be displaceable in unison with the displaceable electrode unit.-

  19. Development of a Double-Gauss Lens Based Setup for Optoacoustic Applications.

    Science.gov (United States)

    Choi, Hojong; Ryu, Jae-Myung; Yeom, Jung-Yeol

    2017-03-03

    In optoacoustic (photoacoustic) systems, different echo signal intensities such as amplitudes, center frequencies, and bandwidths need to be compensated by utilizing variable gain or time-gain compensation amplifiers. However, such electronic components can increase system complexities and signal noise levels. In this paper, we introduce a double-Gauss lens to generate a large field of view with uniform light intensity due to the low chromatic aberrations of the lens, thus obtaining uniform echo signal intensities across the field of view of the optoacoustic system. In order to validate the uniformity of the echo signal intensities in the system, an in-house transducer was placed at various positions above a tissue sample and echo signals were measured and compared with each other. The custom designed double-Gauss lens demonstrated negligible light intensity variation (±1.5%) across the illumination field of view (~2 cm diameter). When the transducer was used to measure echo signal from an eye of a bigeye tuna within a range of ±1 cm, the peak-to-peak amplitude, center frequency, and their -6 dB bandwidth variations were less than 2 mV, 1 MHz, and 6%, respectively. The custom designed double-Gauss lens can provide uniform light beam across a wide area while generating insignificant echo signal variations, and thus can lower the burden of the receiving electronics or signal processing in the optoacoustic system.

  20. Optoacoustic inversion via Volterra kernel reconstruction

    CERN Document Server

    Melchert, O; Roth, B

    2016-01-01

    In this letter we address the numeric inversion of optoacoustic signals to initial stress profiles. Therefore we put under scrutiny the optoacoustic kernel reconstruction problem in the paraxial approximation of the underlying wave-equation. We apply a Fourier-series expansion of the optoacoustic Volterra kernel and obtain the respective expansion coefficients for a given "apparative" setup by performing a gauge procedure using synthetic input data. The resulting effective kernel is subsequently used to solve the optoacoustic source reconstruction problem for general signals. We verify the validity of the proposed inversion protocol for synthetic signals and explore the feasibility of our approach to also account for the diffraction transformation of signals beyond the paraxial approximation.

  1. Opto-acoustic cell permeation

    Energy Technology Data Exchange (ETDEWEB)

    Visuri, S R; Heredia, N

    2000-03-09

    Optically generated acoustic waves have been used to temporarily permeate biological cells. This technique may be useful for enhancing transfection of DNA into cells or enhancing the absorption of locally delivered drugs. A diode-pumped frequency-doubled Nd:YAG laser operating at kHz repetition rates was used to produce a series of acoustic pulses. An acoustic wave was formed via thermoelastic expansion by depositing laser radiation into an absorbing dye. Generated pressures were measured with a PVDF hydrophone. The acoustic waves were transmitted to cultured and plated cells. The cell media contained a selection of normally- impermeable fluorescent-labeled dextran dyes. Following treatment with the opto-acoustic technique, cellular incorporation of dyes, up to 40,000 Molecular Weight, was noted. Control cells that did not receive opto-acoustic treatment had unremarkable dye incorporation. Uptake of dye was quantified via fluorescent microscopic analysis. Trypan Blue membrane exclusion assays and fluorescent labeling assays confirmed the vitality of cells following treatment. This method of enhanced drug delivery has the potential to dramatically reduce required drug dosages and associated side effects and enable revolutionary therapies.

  2. Metamaterials for opto-acoustic interactions

    Science.gov (United States)

    Smith, Michael J. A.; Wolff, Christian; Lapine, Mikhail; de Sterke, C. Martijn; Poulton, Christopher G.

    2017-09-01

    We discuss the use of metamaterials for the creation and enhancement of opto-acoustic interactions. We show that both photo-elastic and the roto-optic components of the opto-acoustic response can be greatly enhanced as a result of artificial terms that arise directly from the interaction of the sub-elements of the structure. This work has important implications for the creation of new photonic devices that are able to efficiently harness Stimulated Brillouin Scattering.

  3. Integrated optical sensors for optoacoustic imaging of tissue

    Science.gov (United States)

    Dmochowski, P.; Hayes-Gill, Barrie R.; Li, C.; Morgan, Stephen P.; Clark, Matt; Crowe, John A.; Somekh, Michael G.

    2004-07-01

    The design of a single integrated lock-in pixel with a logarithmic response for a modulated light camera is described. The sensor has been designed to detect low light levels and can detect modulated light with frequency well above 2 MHz. An n-well photodiode, amplifier, mixer and 150 Hz low-pass filter have been implemented to allow continuous processing of the incident light. The performance of the sensor is demonstrated using an optoacoustic imaging system and tissue phantoms. A 1 MHz ultrasound transducer is used to modulate light scattered through a tissue phantom. An absorbing sphere is scanned through the medium and the improvement in imaging performance provided by ultrasound modulation is demonstrated.

  4. Improved contrast deep optoacoustic imaging using displacement-compensated averaging: breast tumour phantom studies

    Energy Technology Data Exchange (ETDEWEB)

    Jaeger, M; Preisser, S; Kitz, M; Frenz, M [Institute of Applied Physics, University of Bern, Sidlerstrasse 5, CH-3012 Bern (Switzerland); Ferrara, D; Senegas, S; Schweizer, D, E-mail: frenz@iap.unibe.ch [Fukuda Denshi Switzerland AG, Reinacherstrasse 131, CH-4002 Basel (Switzerland)

    2011-09-21

    For real-time optoacoustic (OA) imaging of the human body, a linear array transducer and reflection mode optical irradiation is usually preferred. Such a setup, however, results in significant image background, which prevents imaging structures at the ultimate depth determined by the light distribution and the signal noise level. Therefore, we previously proposed a method for image background reduction, based on displacement-compensated averaging (DCA) of image series obtained when the tissue sample under investigation is gradually deformed. OA signals and background signals are differently affected by the deformation and can thus be distinguished. The proposed method is now experimentally applied to image artificial tumours embedded inside breast phantoms. OA images are acquired alternately with pulse-echo images using a combined OA/echo-ultrasound device. Tissue deformation is accessed via speckle tracking in pulse echo images, and used to compensate in the OA images for the local tissue displacement. In that way, OA sources are highly correlated between subsequent images, while background is decorrelated and can therefore be reduced by averaging. We show that image contrast in breast phantoms is strongly improved and detectability of embedded tumours significantly increased, using the DCA method.

  5. A compact analytic solution describing optoacoustic phenomenon in absorbing fluid

    CERN Document Server

    Cundin, Luisiana; Barsalou, Norman; Voss, Shannon

    2012-01-01

    Derivation of an analytic, closed-form solution for Q-switched laser induced optoacoustic phenomenon in absorbing fluid media is presented. The solution assumes spherical symmetry as well for the forcing function, which represents heat deposition from Q-switched lasers. The Greens solution provided is a suitable kernel to generate more complex solutions arising in optoacoustics, optoacoustic spectroscopy, photoacoustic and photothermal problems.

  6. Macro tree transducers

    NARCIS (Netherlands)

    Engelfriet, Joost; Vogler, Heiko

    1985-01-01

    Macro tree transducers are a combination of top-down tree transducers and macro grammars. They serve as a model for syntax-directed semantics in which context information can be handled. In this paper the formal model of macro tree transducers is studied by investigating typical automata theoretical

  7. Macro tree transducers

    NARCIS (Netherlands)

    Engelfriet, Joost; Vogler, Heiko

    1985-01-01

    Macro tree transducers are a combination of top-down tree transducers and macro grammars. They serve as a model for syntax-directed semantics in which context information can be handled. In this paper the formal model of macro tree transducers is studied by investigating typical automata theoretical

  8. Evaluating Local Elastic Anisotropy of Rocks and Sediments by Means of Optoacoustics While Drilling Oil and Gas Boreholes

    Science.gov (United States)

    Gladilin, A. V.; Egerev, S. V.; Ovchinnikov, O. B.

    2014-12-01

    The optoacoustic method is used to evaluate local elastic anisotropy of rocks and sediments. The method is based on laser sound generation by irradiating a spot on the wall of the oil or gas borehole. The optoacoustic method offers an advantage of precise non-contact placing of a short-pulse point sound source. Pulses of a compression wave, shear waves, and a surface wave are induced in the formation as a result of optoacoustic conversion. The surface trace of the bulk compression wave propagating along the borehole surface has a velocity corresponding to that of a bulk wave. Hence, measurements of the trace propagation time along several predetermined paths on the surface of a borehole provide evaluation of local elastic anisotropy in situ. The pick-up is provided with a piezoelectric ceramic transducer positioned at a predetermined point on the surface of the borehole. The optoacoustic conversion regime parameters were chosen to provide separation of the trace pulse of another surface perturbance at the travel distance of about 0.1 m. The local measurements on the borehole wall are aimed to support accurate depth imaging of seismic data. Understanding these common anisotropy effects is important when interpreting seismic data where they are present.

  9. Optical and opto-acoustic interventional imaging.

    Science.gov (United States)

    Sarantopoulos, Athanasios; Beziere, Nicolas; Ntziachristos, Vasilis

    2012-02-01

    Many clinical interventional procedures, such as surgery or endoscopy, are today still guided by human vision and perception. Human vision however is not sensitive or accurate in detecting a large range of disease biomarkers, for example cellular or molecular processes characteristic of disease. For this reason advanced optical and opto-acoustic (photo-acoustic) methods are considered for enabling a more versatile, sensitive and accurate detection of disease biomarkers and complement human vision in clinical decision making during interventions. Herein, we outline developments in emerging fluorescence and opto-acoustic sensing and imaging techniques that can lead to practical implementations toward improving interventional vision.

  10. Handbook of force transducers

    CERN Document Server

    Stefanescu, Dan Mihai

    2011-01-01

    Part I introduces the basic ""Principles and Methods of Force Measurement"" acording to a classification into a dozen of force transducers types: resistive, inductive, capacitive, piezoelectric, electromagnetic, electrodynamic, magnetoelastic, galvanomagnetic (Hall-effect), vibrating wires, (micro)resonators, acoustic and gyroscopic. Two special chapters refer to force balance techniques and to combined methods in force measurement. Part II discusses the ""(Strain Gauge) Force Transducers Components"", evolving from the classical force transducer to the digital / intelligent one, with the inco

  11. Gas speed flow transducer

    Directory of Open Access Journals (Sweden)

    Godovaniouk V. N.

    2011-08-01

    Full Text Available The design of a gas speed flow transducer using the coupling of gas speed and heat streams within the transducer itself is proposed. To maintain the heat balance between two thermoresistors under gas stream at different temperatures, it provides energy consumption monitoring. The detailed combined planar technology for the transducer production is presented. The worked-out measurement procedure allows to make measurements in the temperature range. Information enough to organize production of cheap, reliable and precise gas speed flow transducers is given.

  12. Picosecond opto-acoustic interferometry and polarimetry in high-index GaAs.

    Science.gov (United States)

    Scherbakov, A V; Bombeck, M; Jäger, J V; Salasyuk, A S; Linnik, T L; Gusev, V E; Yakovlev, D R; Akimov, A V; Bayer, M

    2013-07-15

    By means of a metal opto-acoustic transducer we generate quasi-longitudinal and quasi-transverse picosecond strain pulses in a (311)-GaAs substrate and monitor their propagation by picosecond acoustic interferometry. By probing at the sample side opposite to the transducer the signals related to the compressive and shear strain pulses can be separated in time. In addition to conventional monitoring of the reflected probe light intensity we monitor also the polarization rotation of the optical probe beam. This polarimetric technique results in improved sensitivity of detection and provides comprehensive information about the elasto-optical anisotropy. The experimental observations are in a good agreement with a theoretical analysis.

  13. Modeling of ultrasound transducers

    DEFF Research Database (Denmark)

    Bæk, David

    deviation of 5.5 % to 11.0 %. Finite element modeling of piezoceramics in combination with Field II is addressed and reveals the influence of restricting the modeling of transducers to the one-dimensional case. An investigation on modeling capacitive micromachined ultrasonic transducers (CMUT)s with Field......This Ph.D. dissertation addresses ultrasound transducer modeling for medical ultrasound imaging and combines the modeling with the ultrasound simulation program Field II. The project firstly presents two new models for spatial impulse responses (SIR)s to a rectangular elevation focused transducer...... II is addressed. It is shown how a single circular CMUT cell can be well approximated with a simple square transducer encapsulating the cell, and how this influence the modeling of full array elements. An optimal cell discretization with Field II’s mathematical elements is addressed as well...

  14. Real-time optoacoustic monitoring of stroke

    Science.gov (United States)

    Kneipp, Moritz; Turner, Jake; Hambauer, Sebastian; Krieg, Sandro M.; Lehmberg, Jens; Lindauer, Ute; Razansky, Daniel

    2014-03-01

    Characterizing disease progression and identifying possible therapeutic interventions in stroke is greatly aided by the use of longitudinal function imaging studies. In this study, we investigate the applicability of real-time multispectral optoacoustic tomography (MSOT) as a tool for non-invasive monitoring of the progression of stroke in the whole brain. The middle cerebral artery occlusion (MCAO) method was used to induce stroke. Mice were imaged under isoflurane anesthesia preoperatively and at several time points during and after the 60-minute occlusion. The animals were sacrificed after 24 hours and their excised brains frozen at -80°C for sectioning. The cryosection were stained using H&E staining to identify the ischemic lesion. Major vessels are readily identifiable in the whole mouse head in the in vivo optoacoustic scans. During ischemia, a reduction in cerebral blood volume is detectable in the cortex. Post ischemia, spectral unmixing of the optoacoustic signals shows an asymmetry of the deoxygenated hemoglobin in the hemisphere affected by MCAO. This hypoxic area was mainly located around the boundary of the ischemic lesion and was therefore identified as the ischemic penumbra. Non-invasive functional MSOT imaging is able to visualize the hypoxic penumbra in brains affected by stroke. Stopping the spread of the infarct area and revitalizing the penumbra is central in stroke research, this new imaging technique may therefore prove to be a valuable tool in the monitoring and developing new treatments.

  15. Modeling of phased array transducers.

    Science.gov (United States)

    Ahmad, Rais; Kundu, Tribikram; Placko, Dominique

    2005-04-01

    Phased array transducers are multi-element transducers, where different elements are activated with different time delays. The advantage of these transducers is that no mechanical movement of the transducer is needed to scan an object. Focusing and beam steering is obtained simply by adjusting the time delay. In this paper the DPSM (distributed point source method) is used to model the ultrasonic field generated by a phased array transducer and to study the interaction effect when two phased array transducers are placed in a homogeneous fluid. Earlier investigations modeled the acoustic field for conventional transducers where all transducer points are excited simultaneously. In this research, combining the concepts of delayed firing and the DPSM, the phased array transducers are modeled semi-analytically. In addition to the single transducer modeling the ultrasonic fields from two phased array transducers placed face to face in a fluid medium is also modeled to study the interaction effect. The importance of considering the interaction effect in multiple transducer modeling is discussed, pointing out that neighboring transducers not only act as ultrasonic wave generators but also as scatterers.

  16. Microinterferometer transducer

    Science.gov (United States)

    Corey, III, Harry S.

    1979-01-01

    An air-bearing microinterferometer transducer is provided for increased accuracy, range and linearity over conventional displacement transducers. A microinterferometer system is housed within a small compartment of an air-bearing displacement transducer housing. A movable cube corner reflector of the interferometer is mounted to move with the displacement gauging probe of the transducer. The probe is disposed for axial displacement by means of an air-bearing. Light from a single frequency laser is directed into an interferometer system within the transducer housing by means of a self-focusing fiber optic cable to maintain light coherency. Separate fringe patterns are monitored by a pair of fiber optic cables which transmit the patterns to a detecting system. The detecting system includes a bidirectional counter which counts the light pattern fringes according to the direction of movement of the probe during a displacement gauging operation.

  17. Noninvasive cerebral blood oxygenation monitoring: clinical test of multiwavelength optoacoustic system

    Science.gov (United States)

    Petrov, Y. Y.; Prough, D. S.; Petrova, I.; Patrikeev, I. A.; Cicenaite, I.; Esenaliev, R. O.

    2007-02-01

    Continuous monitoring of cerebral blood oxygenation is critically important for treatment of patients with life-threatening conditions like severe brain injury or during cardiac surgery. We designed and built a novel multiwavelength optoacoustic system for noninvasive, continuous, and accurate monitoring of cerebral blood oxygenation. We use an Optical Parametric Oscillator as a light source. We successfully tested the system in vitro as well as in vivo in large animals (sheep) through thick tissues overlying blood vessels which drain venous blood out of the brain (e.g., superior sagittal sinus or jugular vein). Here we present the results of clinical tests of the system for continuous noninvasive cerebral blood oxygenation monitoring in the internal jugular vein of healthy volunteers. We applied our custom-built optoacoustic probe (which incorporated a wide-band acoustic transducer and an optical fiber) to the neck area overlying the internal jugular vein. We performed measurements with volunteers at 18 wavelengths in the near-infrared spectral range. Despite a thick layer of overlying connective tissue and low energy used in the experiments, we recorded signals with high signal-to-noise ratios for all volunteers. We found that the temporal (independent of signal amplitude) parameters of recorded profiles for different levels of blood oxygenation correlated well with the spectrum of effective attenuation coefficients of blood.

  18. Study of clutter origin in in-vivo epi-optoacoustic imaging of human forearms

    Science.gov (United States)

    Preisser, Stefan; Held, Gerrit; Akarçay, Hidayet G.; Jaeger, Michael; Frenz, Martin

    2016-09-01

    Epi-optoacoustic (OA) imaging offers flexible clinical diagnostics of the human body when the irradiation optic is attached to or directly integrated into the acoustic probe. Epi-OA images, however, encounter clutter that deteriorates contrast and significantly limits imaging depth. This study elaborates clutter origin in clinical epi-optoacoustic imaging using a linear array probe for scanning the human forearm. We demonstrate that the clutter strength strongly varies with the imaging location but stays stable over time, indicating that clutter is caused by anatomical structures. OA transients which are generated by strong optical absorbers located at the irradiation spot were identified to be the main source of clutter. These transients obscure deep in-plane OA signals when detected by the transducer either directly or after being acoustically scattered in the imaging plane. In addition, OA transients generated in the skin below the probe result in acoustic reverberations, which cause problems in image interpretation and limit imaging depth. Understanding clutter origin allows a better interpretation of clinical OA imaging, helps to design clutter compensation techniques and raises the prospect of contrast optimization via the design of the irradiation geometry.

  19. Effects of the murine skull in optoacoustic brain microscopy.

    Science.gov (United States)

    Kneipp, Moritz; Turner, Jake; Estrada, Héctor; Rebling, Johannes; Shoham, Shy; Razansky, Daniel

    2016-01-01

    Despite the great promise behind the recent introduction of optoacoustic technology into the arsenal of small-animal neuroimaging methods, a variety of acoustic and light-related effects introduced by adult murine skull severely compromise the performance of optoacoustics in transcranial imaging. As a result, high-resolution noninvasive optoacoustic microscopy studies are still limited to a thin layer of pial microvasculature, which can be effectively resolved by tight focusing of the excitation light. We examined a range of distortions introduced by an adult murine skull in transcranial optoacoustic imaging under both acoustically- and optically-determined resolution scenarios. It is shown that strong low-pass filtering characteristics of the skull may significantly deteriorate the achievable spatial resolution in deep brain imaging where no light focusing is possible. While only brain vasculature with a diameter larger than 60 µm was effectively resolved via transcranial measurements with acoustic resolution, significant improvements are seen through cranial windows and thinned skull experiments.

  20. Acoustic transducer

    Science.gov (United States)

    Drumheller, Douglas S.

    2000-01-01

    An active acoustic transducer tool for use down-hole applications. The tool includes a single cylindrical mandrel including a shoulder defining the boundary of a narrowed portion over which is placed a sandwich-style piezoelectric tranducer assembly. The piezoelectric transducer assembly is prestressed by being placed in a thermal interference fit between the shoulder of the mandrel and the base of an anvil which is likewise positioned over the narrower portion of the mandrel. In the preferred embodiment, assembly of the tool is accomplished using a hydraulic jack to stretch the mandrel prior to emplacement of the cylindrical sandwich-style piezoelectric transducer assembly and anvil. After those elements are positioned and secured, the stretched mandrel is allowed to return substantially to its original (pre-stretch) dimensions with the result that the piezoelectric transducer elements are compressed between the anvil and the shoulder of the mandrel.

  1. Optical and opto-acoustic imaging.

    Science.gov (United States)

    Ntziachristos, Vasilis; Razansky, Daniel

    2013-01-01

     Since the inception of the microscope, optical imaging is serving the biological discovery for more than four centuries. With the recent emergence of methods appropriate for in vivo staining, such as bioluminescence, fluorescent molecular probes, and proteins, as well as nanoparticle-based targeted agents, significant attention has been shifted toward in vivo interrogations of different dynamic biological processes at the molecular level. This progress has been largely supported by the development of advanced optical tomographic imaging technologies suitable for obtaining volumetric visualization of biomarker distributions in small animals at a whole-body or whole-organ scale, an imaging frontier that is not accessible by the existing tissue-sectioning microscopic techniques due to intensive light scattering beyond the depth of a few hundred microns. Biomedical optoacoustics has also emerged in the recent decade as a powerful tool for high-resolution visualization of optical contrast, overcoming a variety of longstanding limitations imposed by light scattering in deep tissues. By detecting tiny sound vibrations, resulting from selective absorption of light at multiple wavelengths, multispectral optoacoustic tomography methods can now "hear color" in three dimensions, i.e., deliver volumetric spectrally enriched (color) images from deep living tissues at high spatial resolution and in real time. These new-found imaging abilities directly relate to preclinical screening applications in animal models and are foreseen to significantly impact clinical decision making as well.

  2. Whole-body three-dimensional optoacoustic tomography system for small animals

    Science.gov (United States)

    Brecht, Hans-Peter; Su, Richard; Fronheiser, Matthew; Ermilov, Sergey A.; Conjusteau, Andre; Oraevsky, Alexander A.

    2009-11-01

    We develop a system for three-dimensional whole-body optoacoustic tomography of small animals for applications in preclinical research. The tomographic images are obtained while the objects of study (phantoms or mice) are rotated within a sphere outlined by a concave arc-shaped array of 64 piezocomposite transducers. Two pulsed lasers operating in the near-IR spectral range (755 and 1064 nm) with an average pulsed energy of about 100 mJ, a repetition rate of 10 Hz, and a pulse duration of 15 to 75 ns are used as optical illumination sources. During the scan, the mouse is illuminated orthogonally to the array with two wide beams of light from a bifurcated fiber bundle. The system is capable of generating images of individual organs and blood vessels through the entire body of a mouse with spatial resolution of ~0.5 mm.

  3. Investigation of iterative image reconstruction in three-dimensional optoacoustic tomography

    CERN Document Server

    wang, Kun; Oraevsky, Alexander A; Anastasio, Mark A

    2012-01-01

    Iterative image reconstruction algorithms for optoacoustic tomography (OAT), also known as photoacoustic tomography, have the ability to improve image quality over analytic algorithms due to their ability to incorporate accurate models of the imaging physics, instrument response, and measurement noise. However, to date, there have been few reported attempts to employ advanced iterative image reconstruction algorithms for improving image quality in three-dimensional (3D) OAT. In this work, we implement and investigate two iterative image reconstruction methods for use with a 3D OAT small animal imager: namely, a penalized least-squares (PLS) method employing a quadratic smoothness penalty and a PLS method employing a total variation norm penalty. The reconstruction algorithms employ accurate models of the ultrasonic transducer impulse responses. Experimental data sets are employed to compare the performances of the iterative reconstruction algorithms to that of a 3D filtered backprojection (FBP) algorithm. By ...

  4. Investigation of limited-view image reconstruction in optoacoustic tomography employing a priori structural information

    Science.gov (United States)

    Huang, Chao; Oraevsky, Alexander A.; Anastasio, Mark A.

    2010-08-01

    Optoacoustic tomography (OAT) is an emerging ultrasound-mediated biophotonic imaging modality that has exciting potential for many biomedical imaging applications. There is great interest in conducting B-mode ultrasound and OAT imaging studies for breast cancer detection using a common transducer. In this situation, the range of tomographic view angles is limited, which can result in distortions in the reconstructed OAT image if conventional reconstruction algorithms are applied to limited-view measurement data. In this work, we investigate an image reconstruction method that utilizes information regarding target boundaries to improve the quality of the reconstructed OAT images. This is accomplished by developing boundary-constrained image reconstruction algorithm for OAT based on Bayesian image reconstruction theory. The computer-simulation studies demonstrate that the Bayesian approach can effectively reduce the artifact and noise levels and preserve the edges in reconstructed limited-view OAT images as compared to those produced by a conventional OAT reconstruction algorithm.

  5. A wideband combined transducer for measuring system in sound tube%声管测量系统的宽带复合型换能器

    Institute of Scientific and Technical Information of China (English)

    潘耀宗; 莫喜平; 刘永平; 崔政; 张同根

    2011-01-01

    A wideband transducer for sound tube system is presented in this paper, which combines longitudinal transducer and Class IV fiexural transducer to improve the performance at low frequency and broaden the working band. The equivalent electrical circuit is obtained by which the coupling between longitudinal transducer and fiexural transducer is analyzed. A prototype is fabricated after analyzing the electro-acoustic performances by Finite Element Method. The standing wave in the sound tube stimulated by this transducer has been studied and the absorbing coefficients of two samples of acoustic materials are measured using this sound tube, which shows that the transducer can meet the requirements of measuring acoustic materials, especially with the wide working band ranging from 1.4 kHz to 23 kHz.%提出了一种纵向换能器与Ⅳ型弯张换能器相结合的复合型换能器,推导了换能器的等效电路,根据等效电路分析了纵向换能器和弯张换能器之间的耦合作用;应用有限元方法进行了结构优化,使换能器能够发射较高频率声波的同时兼顾低频发射.研制了宽带复合型换能器实验样机,对在声管中所建立的驻波声场特性进行了实验研究,并成功利用该脉冲声管系统进行了声学材料样品的吸声系数测试.通过测试,该换能器可以满足宽频带声学材料测试要求,适用的频率范围为1.4 kHz~23 kHz.

  6. Evaluation and performance enhancement of a pressure transducer under flows, waves, and a combination of flows and waves

    Digital Repository Service at National Institute of Oceanography (India)

    Joseph, A.; Desa, J.A.E.; Foden, P.; Taylor, K.; McKeown, J.; Desa, E.

    in the absence of the shield. For turbulent flows less than 100 cm s sup(-1), a pair of thin, circular, parallel plates, with a diameter three to four times that of the transducer housing and separation equal to the housing diameter, led to a much improved...

  7. Non-invasive optoacoustic probing of the density and stiffness of single biological cells

    Science.gov (United States)

    Dehoux, T.; Audoin, B.

    2012-12-01

    Recently, the coherent generation of GHz acoustic waves using ultrashort laser pulses has demonstrated the ability to probe the sound velocity in vegetal cells and in cell-mimicking soft micro-objects with micrometer resolution, opening tremendous potentialities for single-cell biology. However, manipulating biological media in physiological conditions is often a technical challenge when using a laser-based setup. In this article, we present a new opto-acoustic bio-transducer composed of a thin metal film sputtered on a transparent heat sink that allows reducing importantly the laser-induced cellular stresses, and offers a wide variety of optical configurations. In particular, by exploiting the acoustic reflection coefficient at the sample-transducer interface and the photoacoustic interaction inside the transparent sample, the density and compressibility of the sample can be probed simultaneously. Using an ad hoc signal analysis based on Hilbert and wavelet transforms, these quantities are measured accurately for a reference fluid. Similar analysis performed in a single vegetal cell also suggests high sensitivity to the state of the transducer-cell interface, and notably to the presence of the plasma membrane that encloses the cell vacuole.

  8. Ultrasonic transducer

    Science.gov (United States)

    Taylor, Steven C.; Kraft, Nancy C.

    2007-03-13

    An ultrasonic transducer having an effective center frequency of about 42 MHz; a bandwidth of greater than 85% at 6 dB; a spherical focus of at least 0.5 inches in water; an F4 lens; a resolution sufficient to be able to detect and separate a 0.005 inch flat-bottomed hole at 0.005 inches below surface; and a beam size of approximately 0.006–0.008 inches measured off a 11/2 mm ball in water at the transducer's focal point.

  9. Volumetric optoacoustic monitoring of endovenous laser treatments

    Science.gov (United States)

    Fehm, Thomas F.; Deán-Ben, Xosé L.; Schaur, Peter; Sroka, Ronald; Razansky, Daniel

    2016-03-01

    Chronic venous insufficiency (CVI) is one of the most common medical conditions with reported prevalence estimates as high as 30% in the adult population. Although conservative management with compression therapy may improve the symptoms associated with CVI, healing often demands invasive procedures. Besides established surgical methods like vein stripping or bypassing, endovenous laser therapy (ELT) emerged as a promising novel treatment option during the last 15 years offering multiple advantages such as less pain and faster recovery. Much of the treatment success hereby depends on monitoring of the treatment progression using clinical imaging modalities such as Doppler ultrasound. The latter however do not provide sufficient contrast, spatial resolution and three-dimensional imaging capacity which is necessary for accurate online lesion assessment during treatment. As a consequence, incidence of recanalization, lack of vessel occlusion and collateral damage remains highly variable among patients. In this study, we examined the capacity of volumetric optoacoustic tomography (VOT) for real-time monitoring of ELT using an ex-vivo ox foot model. ELT was performed on subcutaneous veins while optoacoustic signals were acquired and reconstructed in real-time and at a spatial resolution in the order of 200μm. VOT images showed spatio-temporal maps of the lesion progression, characteristics of the vessel wall, and position of the ablation fiber's tip during the pull back. It was also possible to correlate the images with the temperature elevation measured in the area adjacent to the ablation spot. We conclude that VOT is a promising tool for providing online feedback during endovenous laser therapy.

  10. Towards multimodal detection of melanoma thickness based on optical coherence tomography and optoacoustics

    Science.gov (United States)

    Rahlves, M.; Varkentin, A.; Stritzel, J.; Blumenröther, E.; Mazurenka, M.; Wollweber, M.; Roth, B.

    2016-03-01

    Melanoma skin cancer has one of the highest mortality rates of all types of cancer if not detected at an early stage. The survival rate is highly dependent on its penetration depth, which is commonly determined by histopathology. In this work, we aim at combining optical coherence tomography and optoacoustic as a non-invasive all-optical method to measure the penetration depth of melanoma. We present our recent achievements to setup a handheld multimodal device and also results from first in vivo measurements on healthy and cancerous skin tissue, which are compared to measurements obtained by ultrasound and histopathology.

  11. Optoacoustic measurements of human placenta and umbilical blood oxygenation

    Science.gov (United States)

    Nanovskaya, T. N.; Petrov, I. Y.; Petrov, Y.; Patrikeeva, S. L.; Ahmed, M. S.; Hankins, G. D. V.; Prough, D. S.; Esenaliev, R. O.

    2016-03-01

    Adequate oxygenation is essential for normal embryogenesis and fetal growth. Perturbations in the intrauterine oxidative environment during pregnancy are associated with several pathophysiological disorders such as pregnancy loss, preeclampsia, and intrauterine growth restriction. We proposed to use optoacoustic technology for monitoring placental and fetal umbilical blood oxygenation. In this work, we studied optoacoustic monitoring of oxygenation in placenta and umbilical cord blood ex vivo using technique of placenta perfusion. We used a medical grade, nearinfrared, tunable, optoacoustic system developed and built for oxygenation monitoring in blood vessels and in tissues. First, we calibrated the system for cord blood oxygenation measurements by using a CO-Oximeter (gold standard). Then we performed validation in cord blood circulating through the catheters localized on the fetal side of an isolated placental lobule. Finally, the oxygenation measurements were performed in the perfused placental tissue. To increase or decrease blood oxygenation, we used infusion of a gas mixture of 95% O2 + 5% CO2 and 95% N2 + 5% CO2, respectively. In placental tissue, up to four cycles of changes in oxygenation were performed. The optoacoustically measured oxygenation in circulating cord blood and in placental lobule closely correlated with the actual oxygenation data measured by CO-Oximeter. We plan to further test the placental and cord blood oxygenation monitoring with optoacoustics in animal and clinical studies.

  12. Optoacoustic mapping of cerebral blood oxygenation in humans

    Science.gov (United States)

    Petrov, Yuriy; Prough, Donald S.; Petrov, Irene Y.; Richardson, C. Joan; Fonseca, Rafael A.; Robertson, Claudia S.; Esenaliev, Rinat O.

    2017-03-01

    Noninvasive, transcranial mapping, monitoring, and imaging are highly important for detection and management of cerebral abnormalities and neuroscience research. Mapping, imaging, and monitoring of cerebral blood oxygenation are necessary for diagnostics and management of patients with traumatic brain injury, stroke, and other neurological conditions. We proposed to use optoacoustic technology for noninvasive, transcranial monitoring and imaging. In this work, we developed optoacoustic systems for mapping of cerebral blood oxygenation in humans and tested them in adults and neonates. The systems provide noninvasive, transcranial optoacoustic measurements in the transmission (forward) and reflection (backward) modes in the near infrared spectral range. Novel, ultra-sensitive probes were built for detection of optoacoustic signals and measurement of blood oxygenation in neonates and adults. Cerebral oxygenation was measured at different lateral sites from the superior sagittal sinus (SSS), a large central cerebral vein, located immediately beneath the midline of the human skull. In neonates, cerebral oxygenation was measured through open anterior and posterior fontanelles. Optoacoustic signal detection at different locations allowed for mapping of cerebral blood oxygenation. Our future studies will be focused on 3D mapping of cerebral blood oxygenation.

  13. Real-time optoacoustic monitoring of temperature in tissues

    Energy Technology Data Exchange (ETDEWEB)

    Larina, Irina V [Center for Biomedical Engineering, University of Texas Medical Branch, Galveston, TX 77555-0456 (United States); Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, TX 77555-0456 (United States); Larin, Kirill V [Center for Biomedical Engineering, University of Texas Medical Branch, Galveston, TX 77555-0456 (United States); Esenaliev, Rinat O [Center for Biomedical Engineering, University of Texas Medical Branch, Galveston, TX 77555-0456 (United States); Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, TX 77555-0456 (United States); Department of Anesthesiology, University of Texas Medical Branch, Galveston, TX 77555-0456 (United States)

    2005-08-07

    To improve the safety and efficacy of thermal therapy, it is necessary to map tissue temperature in real time with submillimetre spatial resolution. Accurate temperature maps may provide the necessary control of the boundaries of the heated regions and minimize thermal damage to surrounding normal tissues. Current imaging modalities fail to monitor tissue temperature in real time with high resolution and accuracy. We investigated a non-invasive optoacoustic method for accurate, real-time monitoring of tissue temperature during thermotherapy. In this study, we induced temperature gradients in tissue and tissue-like samples and monitored the temperature distribution using the optoacoustic technique. The fundamental harmonic of a Q-switched Nd : YAG laser ({lambda} = 1064 nm) was used for optoacoustic wave generation and probing of tissue temperature. The tissue temperature was also monitored with a multi-sensor temperature probe inserted in the samples. Good agreement between optoacoustically measured and actual tissue temperatures was obtained. The accuracy of temperature monitoring was better than 1{sup 0}C, while the spatial resolution was about 1 mm. These data suggest that the optoacoustic technique has the potential to be used for non-invasive, real-time temperature monitoring during thermotherapy.

  14. Thermal conductivity measurements of non-metals via combined time- and frequency-domain thermoreflectance without a metal film transducer

    Science.gov (United States)

    Wang, L.; Cheaito, R.; Braun, J. L.; Giri, A.; Hopkins, P. E.

    2016-09-01

    The thermoreflectance-based techniques time- and frequency-domain thermoreflectance (TDTR and FDTR, respectively) have emerged as robust platforms to measure the thermophysical properties of a wide array of systems on varying length scales. Routine in the implementation of these techniques is the application of a thin metal film on the surface of the sample of interest to serve as an opto-thermal transducer ensuring the measured modulated reflectivity is dominated by the change in thermoreflectance of the sample. Here, we outline a method to directly measure the thermal conductivities of bulk materials without using a metal transducer layer using a standard TDTR/FDTR experiment. A major key in this approach is the use of a thermal model with z-dependent heat source when the optical penetration depth is comparable to the beam sizes and measuring the FDTR response at a long delay time to minimize non-thermoreflectivity contributions to the modulated reflectance signals (such as free carrier excitations). Using this approach, we demonstrate the ability to measure the thermal conductivity on three semiconductors, intrinsic Si (100), GaAs (100), and InSb (100), the results of which are validated with FDTR measurements on the same wafers with aluminum transducers. We outline the major sources of uncertainty in this approach, including frequency dependent heating and precise knowledge of the pump and probe spot sizes. As a result, we discuss appropriate pump-frequency ranges in which to implement this TDTR/FDTR approach and present a procedure to measure the effective spot sizes by fitting the FDTR data of an 80 nm Al/SiO2 sample at a time delay in which the spot size sensitivity dominates an FDTR measurement over the substrate thermal properties. Our method provides a more convenient way to directly measure the thermal conductivities of semiconductors.

  15. Pressure transducer

    Science.gov (United States)

    Anderson, Thomas T.; Roop, Conard J.; Schmidt, Kenneth J.; Gunchin, Elmer R.

    1989-01-01

    A pressure transducer suitable for use in high temperature environments includes two pairs of induction coils, each pair being bifilarly wound together, and each pair of coils connected as opposite arms of a four arm circuit; an electrically conductive target moveably positioned between the coil pairs and connected to a diaphragm such that deflection of the diaphragm causes axial movement of the target and an unbalance in the bridge output.

  16. Miniature multimode monolithic flextensional transducers.

    Science.gov (United States)

    Hladky-Hennion, Anne-Christine; Uzgur, A Erman; Markley, Douglas C; Safari, Ahmad; Cochran, Joe K; Newnham, Robert E

    2007-10-01

    Traditional flextensional transducers classified in seven groups based on their designs have been used extensively in 1-100 kHz range for mine hunting, fish finding, oil explorations, and biomedical applications. In this study, a new family of small, low cost underwater, and biomedical transducers has been developed. After the fabrication of transducers, finite-elements analysis (FEA) was used extensively in order to optimize these miniature versions of high-power, low-frequency flextensional transducer designs to achieve broad bandwidth for both transmitting and receiving, engineered vibration modes, and optimized acoustic directivity patterns. Transducer topologies with various shapes, cross sections, and symmetries can be fabricated through high-volume, low-cost ceramic and metal extrusion processes. Miniaturized transducers posses resonance frequencies in the range of above 1 MHz to below 10 kHz. Symmetry and design of the transducer, polling patterns, driving and receiving electrode geometries, and driving conditions have a strong effect on the vibration modes, resonance frequencies, and radiation patterns. This paper is devoted to small, multimode flextensional transducers with active shells, which combine the advantages of small size and low-cost manufacturing with control of the shape of the acoustic radiation/receive pattern. The performance of the transducers is emphasized.

  17. An optoacoustic guide with augmented reality system towards precision breast conserving surgery (Conference Presentation)

    Science.gov (United States)

    Lan, Lu; Liu, Kaiming; Xia, Yan; Wu, Jiayingzi; Li, Rui; Wang, Pu; Han, Linda K.; Cheng, Ji-Xin

    2017-02-01

    Breast-conserving surgery is a well-accepted breast cancer treatment. However, it is still challenging for the surgeon to accurately localize the tumor during the surgery. Also, the guidance provided by current methods is 1 dimensional distance information, which is indirect and not intuitive. Therefore, it creates problems on a large re-excision rate, and a prolonged surgical time. To solve these problems, we have developed a fiber-delivered optoacoustic guide (OG), which mimics the traditional localization guide wire and is preoperatively placed into tumor mass, and an augmented reality (AR) system to provide real-time visualization on the location of the tumor with sub-millimeter variance. By a nano-composite light diffusion sphere and light absorbing layer formed on the tip of an optical fiber, the OG creates an omnidirectional acoustic source inside tumor mass under pulsed laser excitation. The optoacoustic signal generated has a high dynamic range ( 58dB) and spreads in a large apex angle of 320 degrees. Then, an acoustic radar with three ultrasound transducers is attached to the breast skin, and triangulates the location of the OG tip. With an AR system to sense the location of the acoustic radar, the relative position of the OG tip inside the tumor to the AR display is calculated and rendered. This provides direct visual feedback of the tumor location to surgeons, which will greatly ease the surgical planning during the operation and save surgical time. A proof-of-concept experiment using a tablet and a stereo-vision camera is demonstrated and 0.25 mm tracking variance is achieved.

  18. Multispectral optoacoustic tomography resolves smart probe activation in vulnerable plaques

    Science.gov (United States)

    Razansky, Daniel; Harlaar, Niels J.; Hillebrands, Jan-Luuk; Taruttis, Adrian; Herzog, Eva; Zeebregts, Clark; van Dam, Goitzen; Ntziachristos, Vasilis

    2011-03-01

    In this work, we show, for the first time to our knowledge, that multispectral optoacoustic tomography (MSOT) can deliver high resolution images of activatable molecular probe's distribution, sensitive to matrix metalloproteinases (MMP), deep within optically scattering human carotid specimen. It is further demonstrated that this method can be used in order to provide accurate maps of vulnerable plaque formations in atherosclerotic disease. Moreover, optoacoustic images can simultaneously show the underlining plaque morphology for accurate localization of MMP activity in three dimensions. This performance directly relates to small animal screening applications and to clinical potential as well.

  19. All-optical optoacoustic microscopy based on probe beam deflection technique

    Directory of Open Access Journals (Sweden)

    Saher M. Maswadi

    2016-09-01

    Full Text Available Optoacoustic (OA microscopy using an all-optical system based on the probe beam deflection technique (PBDT for detection of laser-induced acoustic signals was investigated as an alternative to conventional piezoelectric transducers. PBDT provides a number of advantages for OA microscopy including (i efficient coupling of laser excitation energy to the samples being imaged through the probing laser beam, (ii undistorted coupling of acoustic waves to the detector without the need for separation of the optical and acoustic paths, (iii high sensitivity and (iv ultrawide bandwidth. Because of the unimpeded optical path in PBDT, diffraction-limited lateral resolution can be readily achieved. The sensitivity of the current PBDT sensor of 22 μV/Pa and its noise equivalent pressure (NEP of 11.4 Pa are comparable with these parameters of the optical micro-ring resonator and commercial piezoelectric ultrasonic transducers. Benefits of the present prototype OA microscope were demonstrated by successfully resolving micron-size details in histological sections of cardiac muscle.

  20. Non-invasive volumetric optoacoustic imaging of cardiac cycles in acute myocardial infarction model in real-time

    Science.gov (United States)

    Lin, Hasiao-Chun Amy; Déan-Ben, Xosé Luís.; Kimm, Melanie; Kosanke, Katja; Haas, Helena; Meier, Reinhard; Lohöfer, Fabian; Wildgruber, Moritz; Razansky, Daniel

    2017-03-01

    Extraction of murine cardiac functional parameters on a beat-by-beat basis remains challenging with the existing imaging modalities. Novel methods enabling in vivo characterization of functional parameters at a high temporal resolution are poised to advance cardiovascular research and provide a better understanding of the mechanisms underlying cardiac diseases. We present a new approach based on analyzing contrast-enhanced optoacoustic (OA) images acquired at high volumetric frame rate without using cardiac gating or other approaches for motion correction. Acute myocardial infarction was surgically induced in murine models, and the method was modified to optimize for acquisition of artifact-free optoacoustic data. Infarcted hearts could be differentiated from healthy controls based on a significantly higher pulmonary transit time (PTT: infarct 2.07 s vs. healthy 1.34 s), while no statistically significant difference was observed in the heart rate (318 bpm vs. 309 bpm). In combination with the proven ability of optoacoustics to track targeted probes within the injured myocardium, our method is capable of depicting cardiac anatomy, function, and molecular signatures on a beat-by-beat basis, both with high spatial and temporal resolution, thus providing new insights into the study of myocardial ischemia.

  1. Functional real-time optoacoustic imaging of middle cerebral artery occlusion in mice.

    Directory of Open Access Journals (Sweden)

    Moritz Kneipp

    Full Text Available BACKGROUND AND PURPOSE: Longitudinal functional imaging studies of stroke are key in identifying the disease progression and possible therapeutic interventions. Here we investigate the applicability of real-time functional optoacoustic imaging for monitoring of stroke progression in the whole brain of living animals. MATERIALS AND METHODS: The middle cerebral artery occlusion (MCAO was used to model stroke in mice, which were imaged preoperatively and the occlusion was kept in place for 60 minutes, after which optoacoustic scans were taken at several time points. RESULTS: Post ischemia an asymmetry of deoxygenated hemoglobin in the brain was observed as a region of hypoxia in the hemisphere affected by the ischemic event. Furthermore, we were able to visualize the penumbra in-vivo as a localized hemodynamically-compromised area adjacent to the region of stroke-induced perfusion deficit. CONCLUSION: The intrinsic sensitivity of the new imaging approach to functional blood parameters, in combination with real time operation and high spatial resolution in deep living tissues, may see it become a valuable and unique tool in the development and monitoring of treatments aimed at suspending the spread of an infarct area.

  2. Circuit for Driving Piezoelectric Transducers

    Science.gov (United States)

    Randall, David P.; Chapsky, Jacob

    2009-01-01

    The figure schematically depicts an oscillator circuit for driving a piezoelectric transducer to excite vibrations in a mechanical structure. The circuit was designed and built to satisfy application-specific requirements to drive a selected one of 16 such transducers at a regulated amplitude and frequency chosen to optimize the amount of work performed by the transducer and to compensate for both (1) temporal variations of the resonance frequency and damping time of each transducer and (2) initially unknown differences among the resonance frequencies and damping times of different transducers. In other words, the circuit is designed to adjust itself to optimize the performance of whichever transducer is selected at any given time. The basic design concept may be adaptable to other applications that involve the use of piezoelectric transducers in ultrasonic cleaners and other apparatuses in which high-frequency mechanical drives are utilized. This circuit includes three resistor-capacitor networks that, together with the selected piezoelectric transducer, constitute a band-pass filter having a peak response at a frequency of about 2 kHz, which is approximately the resonance frequency of the piezoelectric transducers. Gain for generating oscillations is provided by a power hybrid operational amplifier (U1). A junction field-effect transistor (Q1) in combination with a resistor (R4) is used as a voltage-variable resistor to control the magnitude of the oscillation. The voltage-variable resistor is part of a feedback control loop: Part of the output of the oscillator is rectified and filtered for use as a slow negative feedback to the gate of Q1 to keep the output amplitude constant. The response of this control loop is much slower than 2 kHz and, therefore, does not introduce significant distortion of the oscillator output, which is a fairly clean sine wave. The positive AC feedback needed to sustain oscillations is derived from sampling the current through the

  3. Investigation of iterative image reconstruction in three-dimensional optoacoustic tomography

    Science.gov (United States)

    Wang, Kun; Su, Richard; Oraevsky, Alexander A.; Anastasio, Mark A.

    2012-09-01

    Iterative image reconstruction algorithms for optoacoustic tomography (OAT), also known as photoacoustic tomography, have the ability to improve image quality over analytic algorithms due to their ability to incorporate accurate models of the imaging physics, instrument response and measurement noise. However, to date, there have been few reported attempts to employ advanced iterative image reconstruction algorithms for improving image quality in three-dimensional (3D) OAT. In this work, we implement and investigate two iterative image reconstruction methods for use with a 3D OAT small animal imager: namely a penalized least-squares (PLS) method employing a quadratic smoothness penalty and a PLS method employing a total variation norm penalty. The reconstruction algorithms employ accurate models of the ultrasonic transducer impulse responses. Experimental data sets are employed to compare the performances of the iterative reconstruction algorithms to that of a 3D filtered backprojection (FBP) algorithm. By the use of quantitative measures of image quality, we demonstrate that the iterative reconstruction algorithms can mitigate image artifacts and preserve spatial resolution more effectively than FBP algorithms. These features suggest that the use of advanced image reconstruction algorithms can improve the effectiveness of 3D OAT while reducing the amount of data required for biomedical applications.

  4. High contrast imaging of reversibly switchable fluorescent proteins via temporally unmixed Multispectral Optoacoustic Tomography (tuMSOT)

    CERN Document Server

    Stiel, Andre C; Jiang, Yuanyuan; Ntziachristos, Vasilis; Razansky, Daniel; Westmeyer, Gil G

    2014-01-01

    Photocontrol of reversibly switchable fluorescent proteins (RSFPs) was used to program optoacoustic signal time courses that were temporally unmixed to increase the proteins contrast-to-noise-ratios (CNRs) in optoacoustic imaging. In this way, two variants of the RSFP Dronpa with very similar optoacoustic spectra could be readily discriminated in the presence of highly absorbing blood. Addition of temporal unmixing to multispectral optoacoustic tomography (tuMSOT) in conjunction with synthetic or genetically controlled photochromic contrast agents and customized photoswitching schedules can increase the performance of multiplexed and high contrast molecular optoacoustic imaging.

  5. The Effect of Internal Relaxation on Optoacoustic Conversion in Liquids.

    Science.gov (United States)

    1988-02-05

    optical energy the time dependance of the acoustic pressure is determined by the size and shape of the excitation zone. This research was concerned with the...excitation zone in determining the time dependance of the acoustic pressure, and to 20 DISTRIBUTION /AVAILABILITY OF ABSTRACT 21 ABSTRACT SECURITY...considerations, which accurately predict the optoacoustic signal in such cases. The results show that for a short pulse of optical energy the time dependance of

  6. Opto-acoustic breast imaging with co-registered ultrasound

    Science.gov (United States)

    Zalev, Jason; Clingman, Bryan; Herzog, Don; Miller, Tom; Stavros, A. Thomas; Oraevsky, Alexander; Kist, Kenneth; Dornbluth, N. Carol; Otto, Pamela

    2014-03-01

    We present results from a recent study involving the ImagioTM breast imaging system, which produces fused real-time two-dimensional color-coded opto-acoustic (OA) images that are co-registered and temporally inter- leaved with real-time gray scale ultrasound using a specialized duplex handheld probe. The use of dual optical wavelengths provides functional blood map images of breast tissue and tumors displayed with high contrast based on total hemoglobin and oxygen saturation of the blood. This provides functional diagnostic information pertaining to tumor metabolism. OA also shows morphologic information about tumor neo-vascularity that is complementary to the morphological information obtained with conventional gray scale ultrasound. This fusion technology conveniently enables real-time analysis of the functional opto-acoustic features of lesions detected by readers familiar with anatomical gray scale ultrasound. We demonstrate co-registered opto-acoustic and ultrasonic images of malignant and benign tumors from a recent clinical study that provide new insight into the function of tumors in-vivo. Results from the Feasibility Study show preliminary evidence that the technology may have the capability to improve characterization of benign and malignant breast masses over conventional diagnostic breast ultrasound alone and to improve overall accuracy of breast mass diagnosis. In particular, OA improved speci city over that of conventional diagnostic ultrasound, which could potentially reduce the number of negative biopsies performed without missing cancers.

  7. Wavefront shaping based on three-dimensional optoacoustic feedback

    Science.gov (United States)

    Deán-Ben, X. L.; Estrada, Héctor; Ozbek, Ali; Razansky, Daniel

    2015-07-01

    Wavefront shaping techniques have recently evolved as a promising tool to control the light distribution in optically-scattering media. These techniques are based on spatially-modulating the phase of an incident light beam to create positive interference (focusing) at specific locations in the speckle pattern of the scattered wavefield. The optimum phase distribution (mask) of the spatial light modulator that allows focusing at the target location(s) is determined iteratively by monitoring the light intensity at such target. In this regard, optoacoustic (photoacoustic) imaging may provide the convenient advantage of simultaneous feedback information on light distribution in an entire region of interest. Herein, we showcase that volumetric optoacoustic images can effectively be used as a feedback mechanism in an iterative optimization algorithm allowing controlling the light distribution after propagation through a scattering sample. Experiments performed with absorbing microparticles distributed in a three-dimensional region showcase the feasibility of enhancing the light intensity at specific points. The advantages provided by optoacoustic imaging in terms of spatial and temporal resolution anticipate new capabilities of wavefront shaping techniques in biomedical optics.

  8. Combined immunotherapy with granulocyte-macrophage colony-stimulating factor-transduced allogeneic prostate cancer cells and ipilimumab in patients with metastatic castration-resistant prostate cancer: a phase 1 dose-escalation trial

    NARCIS (Netherlands)

    Eertwegh, A.J. van den; Versluis, J.; Berg, H.P. van den; Santegoets, S.J.; Moorselaar, R.J. van; Sluis, T.M. van der; Gall, H.E.; Harding, T.C.; Jooss, K.; Lowy, I.; Pinedo, H.M.; Scheper, R.J.; Stam, A.G.; Blomberg, B.M. von; Gruijl, T.D. de; Hege, K.; Sacks, N.; Gerritsen, W.R.

    2012-01-01

    BACKGROUND: The granulocyte-macrophage colony-stimulating factor-transduced allogeneic prostate cancer cells vaccine (GVAX) has antitumour activity against prostate cancer; preclinical studies have shown potent synergy when combined with ipilimumab, an antibody that blocks cytotoxic T-lymphocyte ant

  9. Quantitative imaging of tumor vasculature using multispectral optoacoustic tomography (MSOT)

    Science.gov (United States)

    Tomaszewski, Michal R.; Quiros-Gonzalez, Isabel; Joseph, James; Bohndiek, Sarah E.

    2017-03-01

    The ability to evaluate tumor oxygenation in the clinic could indicate prognosis and enable treatment monitoring, since oxygen deficient cancer cells are often more resistant to chemotherapy and radiotherapy. MultiSpectral Optoacoustic Tomography (MSOT) is a hybrid technique combining the high contrast of optical imaging with spatial resolution and penetration depth similar to ultrasound. We hypothesized that MSOT could reveal both tumor vascular density and function based on modulation of blood oxygenation. We performed MSOT on nude mice (n=8) bearing subcutaneous xenograft PC3 tumors using an inVision 256 (iThera Medical). The mice were maintained under inhalation anesthesia during imaging and respired oxygen content was modified from 21% to 100% and back. After imaging, Hoechst 33348 was injected to indicate vascular perfusion and permeability. Tumors were then extracted for histopathological analysis and fluorescence microscopy. The acquired data was analyzed to extract a bulk measurement of blood oxygenation (SO2MSOT) from the whole tumor using different approaches. The tumors were also automatically segmented into 5 regions to investigate the effect of depth on SO2MSOT. Baseline SO2MSOT values at 21% and 100% oxygen breathing showed no relationship with ex vivo measures of vascular density or function, while the change in SO2MSOT showed a strong negative correlation to Hoechst intensity (r=- 0.92, p=0.0016). Tumor voxels responding to oxygen challenge were spatially heterogeneous. We observed a significant drop in SO2 MSOT value with tumor depth following a switch of respiratory gas from air to oxygen (0.323+/-0.017 vs. 0.11+/-0.05, p=0.009 between 0 and 1.5mm depth), but no such effect for air breathing (0.265+/-0.013 vs. 0.19+/-0.04, p=0.14 between 0 and 1.5mm depth). Our results indicate that in subcutaneous prostate tumors, baseline SO2MSOT levels do not correlate to tumor vascular density or function while the magnitude of the response to oxygen

  10. Megahertz tonpilz transducer

    Science.gov (United States)

    Van Tol, Dave; Hughes, W. Jack

    1999-06-01

    The tonpilz configuration is applied to a transducer operating in the megahertz frequency range. The KLM model is used to design the transducer using readily available components. The construction techniques used are the same as those applied to standard high frequency transducers. Modeled and measured pulse-echo results display a high level of agreement, but impedance and sensitivity comparisons are less promising.

  11. Direct and inverse solver for the 3D optoacoustic Volterra equation

    CERN Document Server

    Stritzel, J; Wollweber, M; Roth, B

    2016-01-01

    The direct problem of optoacoustic signal generation in biological media consists of solving the inhomogeneous optoacoustic wave equation for an initial acoustic stress profile. In contrast, the mathematically challenging inverse problem requires the reconstruction of the initial stress profile from a proper set of observed signals. In this article, we consider the particular case of a Gaussian transverse irradiation source profile in the paraxial approximation of the wave equation, for which the direct problem along the beam axis can be cast into a linear Volterra integral equation of the second kind. This integral equation can be used in two ways: as a forward solver to predict optoacoustic signals in terms of the direct problem, and as an inverse solver for which we here devise highly efficient numerical schemes used for the reconstruction of initial pressure profiles from observed signals, constituting a methodical progress of computational aspects of optoacoustics. In this regard, we explore the validity...

  12. Cerebral blood oxygenation measurements in neonates with optoacoustic technique

    Science.gov (United States)

    Herrmann, Stephen; Petrov, Irene Y.; Petrov, Yuriy; Richardson, C. Joan; Fonseca, Rafael A.; Prough, Donald S.; Esenaliev, Rinat O.

    2017-03-01

    Cerebral hypoxia is a major contributor to neonatal/infant mortality and morbidity including severe neurological complications such as mental retardation, cerebral palsy, motor impairment, and epilepsy. Currently, no technology is capable of accurate monitoring of neonatal cerebral oxygenation. We proposed to use optoacoustics for this application by probing the superior sagittal sinus (SSS), a large central cerebral vein. We developed and built a multi-wavelength, optical parametric oscillator (OPO) and laser diode optoacoustic systems for measurement of SSS blood oxygenation in the reflection mode through open anterior or posterior fontanelles and in the transmission mode through the skull in the occipital area. In this paper we present results of initial tests of the laser diode system for neonatal cerebral oxygenation measurements. First, the system was tested in phantoms simulating neonatal SSS. Then, using the data obtained in the phantoms, we optimized the system's hardware and software and tested it in neonates admitted in the Neonatal Intensive Care Unit. The laser diode system was capable of detecting SSS signals in the reflection mode through the open anterior and posterior fontanelles as well as in the transmission mode through the skull with high signal-to-noise ratio. Using the signals measured at different wavelengths and algorithms developed for oxygenation measurements, the laser diode system provided real-time, continuous oxygenation monitoring with high precision at all these locations.

  13. Noninvasive optoacoustic system for rapid diagnostics and management of circulatory shock

    Science.gov (United States)

    Esenaliev, Rinat O.; Petrov, Irene Y.; Petrov, Yuriy; Kinsky, Michael; Prough, Donald S.

    2012-02-01

    Circulatory shock is lethal, if not promptly diagnosed and effectively treated. Typically, circulatory shock resuscitation is guided by blood pressure, heart rate, and mental status, which have poor predictive value. In patients, in whom early goaldirected therapy was applied using central venous oxygenation measurement, a substantial reduction of mortality was reported (from 46.5% to 30%). However, central venous catheterization is invasive, time-consuming and often results in complications. We proposed to use the optoacoustic technique for noninvasive, rapid assessment of central venous oxygenation. In our previous works we demonstrated that the optoacoustic technique can provide measurement of blood oxygenation in veins and arteries due to high contrast and high resolution. In this work we developed a novel optoacoustic system for noninvasive, automatic, real-time, and continuous measurement of central venous oxygenation. We performed pilot clinical tests of the system in human subjects with different oxygenation in the internal jugular vein and subclavian vein. A novel optoacoustic interface incorporating highly-sensitive optoacoustic probes and standard ultrasound imaging probes were developed and built for the study. Ultrasound imaging systems Vivid i and hand-held Vscan (GE Healthcare) as well as Site-Rite 5 (C.R. Bard) were used in the study. We developed a special algorithm for oxygenation monitoring with minimal influence of overlying tissue. The data demonstrate that the system provides precise measurement of venous oxygenation continuously and in real time. Both current value of the venous oxygenation and trend (in absolute values and for specified time intervals) are displayed in the system. The data indicate that: 1) the optoacoustic system developed by our group is capable of noninvasive measurement of blood oxygenation in specific veins; 2) clinical ultrasound imaging systems can facilitate optoacoustic probing of specific blood vessels; 3) the

  14. Model of a Piezoelectric Transducer

    Science.gov (United States)

    Goodenow, Debra

    2004-01-01

    It's difficult to control liquid and gas in propellant tanks in zero gravity. A possible a design would utilize acoustic liquid manipulation (ALM) technology which uses ultrasonic beams conducted through a liquid and solid media, to push gas bubbles in the liquid to desirable locations. We can propel and control the bubble with acoustic radiation pressure by aiming the acoustic waves on the bubble s surface. This allows us to design a so called smart tank in which the ALM devices transfer the gas to the outer wall of the tank and isolating the liquid in the center. Because the heat transfer rate of a gas is lower of that of the liquid it would substantially decrease boil off and provide of for a longer storage life. The ALM beam is composed of little wavelets which are individual waves that constructively interfere with each other to produce a single, combined acoustic wave front. This is accomplished by using a set of synchronized ultrasound transducers arranged in an array. A slight phase offset of these elements allows us to focus and steer the beam. The device that we are using to produce the acoustic beam is called the piezoelectric transducer. This device converts electrical energy to mechanical energy, which appears in the form of acoustic energy. Therefore the behavior of the device is dependent on both the mechanical characteristics, such as its density, cross-sectional area, and its electrical characteristics, such as, electric flux permittivity and coupling factor. These devices can also be set up in a number of modes which are determined by the way the piezoelectric device is arranged, and the shape of the transducer. For this application we are using the longitudinal or thickness mode for our operation. The transducer also vibrates in the lateral mode, and one of the goals of my project is to decrease the amount of energy lost to the lateral mode. To model the behavior of the transducers I will be using Pspice, electric circuit modeling tool, to

  15. Driving electrostatic transducers

    DEFF Research Database (Denmark)

    Nielsen, Dennis; Knott, Arnold; Andersen, Michael A. E.

    2013-01-01

    Electrostatic transducers represent a very interesting alternative to the traditional inefficient electrodynamic transducers. In order to establish the full potential of these transducers, power amplifiers which fulfill the strict requirements imposed by such loads (high impedance, frequency...... depended, nonlinear and high bias voltage for linearization) must be developed. This paper analyzes power stages and bias configurations suitable for driving an electrostatic transducer. Measurement results of a 300 V prototype amplifier are shown. Measuring THD across a high impedance source is discussed......, and a high voltage attenuation interface for an audio analyzer is presented. THD below 0:1% is reported....

  16. Generating arbitrary ultrasound fields with tailored optoacoustic surface profiles

    Science.gov (United States)

    Brown, M. D.; Nikitichev, D. I.; Treeby, B. E.; Cox, B. T.

    2017-02-01

    Acoustic fields with multiple foci have many applications in physical acoustics ranging from particle manipulation to neural modulation. However, the generation of multiple foci at arbitrary locations in three-dimensional is challenging using conventional transducer technology. In this work, the optical generation of acoustic fields focused at multiple points using a single optical pulse is demonstrated. This is achieved using optically absorbing surface profiles designed to generate specific, user-defined, wavefields. An optimisation approach for the design of these tailored surface profiles is developed. This searches for a smoothly varying surface that will generate a high peak pressure at a set of target focal points. The designed surface profiles are then realised via a combination of additive manufacturing and absorber deposition techniques. Acoustic field measurements from a sample designed to generate the numeral "7" are used to demonstrate the design method.

  17. An Inexpensive Position Transducer.

    Science.gov (United States)

    Fox, J.; And Others

    1989-01-01

    Described is a position transducer used to convert the position of an object into a voltage read by a computer with use of an interface board. The arrangement of the apparatus, electronic circuit, and typical graph displays are presented. Discussed is the instructional use of the transducer. (YP)

  18. Triple-resonant transducers.

    Science.gov (United States)

    Butler, Stephen C

    2012-06-01

    A detailed analysis is presented of two novel multiple-resonant transducers which produce a wider transmit response than that of a conventional Tonpilz-type transducer. These multi-resonant transducers are Tonpilz-type longitudinal vibrators that produce three coupled resonances and are referred to as triple-resonant transducers (TRTs). One of these designs is a mechanical series arrangement of a tail mass, piezoelectric ceramic stack, central mass, compliant spring, second central mass, second compliant spring, and a piston-radiating head mass. The other TRT design is a mechanical series arrangement of a tail mass, piezoelectric ceramic stack, central mass, compliant spring, and head mass with a quarter-wave matching layer of poly(methyl methacrylate) on the head mass. Several prototype transducer element designs were fabricated that demonstrated proof-of-concept.

  19. Programming macro tree transducers

    DEFF Research Database (Denmark)

    Bahr, Patrick; Day, Laurence E.

    2013-01-01

    A tree transducer is a set of mutually recursive functions transforming an input tree into an output tree. Macro tree transducers extend this recursion scheme by allowing each function to be defined in terms of an arbitrary number of accumulation parameters. In this paper, we show how macro tree...... transducers can be concisely represented in Haskell, and demonstrate the benefits of utilising such an approach with a number of examples. In particular, tree transducers afford a modular programming style as they can be easily composed and manipulated. Our Haskell representation generalises the original...... definition of (macro) tree transducers, abolishing a restriction on finite state spaces. However, as we demonstrate, this generalisation does not affect compositionality....

  20. Programming macro tree transducers

    DEFF Research Database (Denmark)

    Bahr, Patrick; Day, Laurence E.

    2013-01-01

    A tree transducer is a set of mutually recursive functions transforming an input tree into an output tree. Macro tree transducers extend this recursion scheme by allowing each function to be defined in terms of an arbitrary number of accumulation parameters. In this paper, we show how macro tree...... transducers can be concisely represented in Haskell, and demonstrate the benefits of utilising such an approach with a number of examples. In particular, tree transducers afford a modular programming style as they can be easily composed and manipulated. Our Haskell representation generalises the original...... definition of (macro) tree transducers, abolishing a restriction on finite state spaces. However, as we demonstrate, this generalisation does not affect compositionality....

  1. Compact Orthomode Transducers Using Digital Polarization Synthesis

    CERN Document Server

    Morgan, Matthew A; Boyd, Tod A

    2010-01-01

    In this paper we present a novel class of compact orthomode transducers which use digital calibration to synthesize the desired polarization vectors while maintaining high isolation and minimizing mass and volume. These digital orthomode transducers consist of an arbitrary number of planar probes in a circular waveguide, each of which is connected to an independent receiver chain designed for stability of complex gain. The outputs of each receiver chain are then digitized and combined numerically with calibrated, complex coefficients. Measurements on two prototype digital orthomode transducers, one with three probes and one with four, show better than 50 dB polarization isolation over a 10 C temperature range with a single calibration.

  2. Opto-acoustic recanilization delivery system

    Energy Technology Data Exchange (ETDEWEB)

    Visuri, Steven R. (Livermore, CA); Da Silva, Luiz B. (Danville, CA); Celliers, Peter M. (Berkeley, CA); London, Richard A. (Orinda, CA); Benett, William (Livermore, CA); Broughton, Kathryn (Berkeley, CA); Esch, Victor (San Francisco, CA)

    2002-01-01

    Fiber delivered laser pulses emulsify thrombus by mechanical stresses that include a combination of pressure, tension and shear stress. Laser radiation is delivered to the locality of a thrombus and the radiation is absorbed by blood, blood dot, or other present materials. The combination of a leading pressure wave and subsequent vapor bubble cause efficient, emulsification of thrombus. Operating the laser in a low average power mode alleviates potential thermal complications. The laser is operated in a high repetition rate mode to take advantage of ultrasound frequency effects of thrombus dissolution as well as to decrease the total procedure time. Specific parameter ranges for operation are described. The device includes optical fibers surrounding a lumen intended for flow of a cooling agent. The fibers may be arranged concentrically around the lumen to deliver radiation and heat over as large an area as possible. An alternative design approach incorporates the optical fibers into the wall of the guiding catheter and utilizes the catheter lumen as the cooling channel. An eccentric tip enables rotation of the device to address all parts of the vasculature. The eccentricity can be provided via a variety of means: spring dip, balloon, protrusion, etc.

  3. Hybrid microscopy of human carotid atheroma by means of optical-resolution optoacoustic and non-linear optical microscopy

    Science.gov (United States)

    Seeger, Markus; Karlas, Angelos; Soliman, Dominik; Pelisek, Jaroslav; Ntziachristos, Vasilis

    2017-03-01

    Carotid atheromatosis is causally related to stroke, a leading cause of disability and death. We present the analysis of a human carotid atheroma using a novel hybrid microscopy system that combines optical-resolution optoacoustic (photoacoustic) microscopy and several non-linear optical microscopy modalities (second and third harmonic generation, as well as, two-photon excitation fluorescence) to achieve a multimodal examination of the extracted tissue within the same imaging framework. Our system enables the label-free investigation of atheromatous human carotid tissue with a resolution of about 1 μm and allows for the congruent interrogation of plaque morphology and clinically relevant constituents such as red blood cells, collagen, and elastin. Our data reveal mutual interactions between blood embeddings and connective tissue within the atheroma, offering comprehensive insights into its stage of evolution and severity, and potentially facilitating the further development of diagnostic tools, as well as treatment strategies.

  4. Compact Transducers and Arrays

    Science.gov (United States)

    2005-05-01

    Soc. Am., 104, pp.64-71 44 25.Decarpigny, J.N., J.C. Debus, B. Tocquet & D. Boucher. 1985. "In-Air Analysis Of Piezoelectric Tonpilz Transducers In A... Transducers and Arrays Final Report May 2005 Contacts: Dr. Robert E. Newnham The Pennsylvania State University, 251 MRL, University Park, PA 16802 phone...814) 865-1612 fax: (814) 865-2326 email: ....c xx.....i.i.....ht.. .u a.p.u..c.e.du. Dr. Richard J. Meyer, Jr. Systems Engineering ( Transducers ), ARL

  5. Optoacoustic 3D visualization of changes in physiological properties of mouse tissues from live to postmortem

    Science.gov (United States)

    Su, Richard; Ermiliov, Sergey A.; Liopo, Anton V.; Oraevsky, Alexander A.

    2012-02-01

    Using the method of 3D optoacoustic tomography, we studied changes in tissues of the whole body of nude mice as the changes manifested themselves from live to postmortem. The studies provided the necessary baseline for optoacoustic imaging of necrotizing tissue, acute and chronic hypoxia, and reperfusion. They also establish a new optoacoustic model of early postmortem conditions of the whole mouse body. Animals were scanned in a 37°C water bath using a three-dimensional optoacoustic tomography system previously shown to provide high contrast maps of vasculature and organs based on changes in the optical absorbance. The scans were performed right before, 5 minutes after, 2 hours and 1 day after a lethal injection of KCl. The near-infrared laser wavelength of 765 nm was used to evaluate physiological features of postmortem changes. Our data showed that optoacoustic imaging is well suited for visualization of both live and postmortem tissues. The images revealed changes of optical properties in mouse organs and tissues. Specifically, we observed improvements in contrast of the vascular network and organs after the death of the animal. We associated these with reduced optical scattering, loss of motion artifacts, and blood coagulation.

  6. Four dimensional optoacoustic imaging of perfusion in preclinical breast tumor model in vivo (Conference Presentation)

    Science.gov (United States)

    Deán-Ben, Xosé Luís.; Ermolayev, Vladimir; Mandal, Subhamoy; Ntziachristos, Vasilis; Razansky, Daniel

    2016-03-01

    Imaging plays an increasingly important role in clinical management and preclinical studies of cancer. Application of optical molecular imaging technologies, in combination with highly specific contrast agent approaches, eminently contributed to understanding of functional and histological properties of tumors and anticancer therapies. Yet, optical imaging exhibits deterioration in spatial resolution and other performance metrics due to light scattering in deep living tissues. High resolution molecular imaging at the whole-organ or whole-body scale may therefore bring additional understanding of vascular networks, blood perfusion and microenvironment gradients of malignancies. In this work, we constructed a volumetric multispectral optoacoustic tomography (vMSOT) scanner for cancer imaging in preclinical models and explored its capacity for real-time 3D intravital imaging of whole breast cancer allografts in mice. Intrinsic tissue properties, such as blood oxygenation gradients, along with the distribution of externally administered liposomes carrying clinically-approved indocyanine green dye (lipo-ICG) were visualized in order to study vascularization, probe penetration and extravasation kinetics in different regions of interest within solid tumors. The use of v-MSOT along with the application of volumetric image analysis and perfusion tracking tools for studies of pathophysiological processes within microenvironment gradients of solid tumors demonstrated superior volumetric imaging system performance with sustained competitive resolution and imaging depth suitable for investigations in preclinical cancer models.

  7. Hybrid ultrasound and dual-wavelength optoacoustic biomicroscopy for functional neuroimaging

    Science.gov (United States)

    Rebling, Johannes; Estrada, Hector; Zwack, Michael; Sela, Gali; Gottschalk, Sven; Razansky, Daniel

    2017-03-01

    Many neurological disorders are linked to abnormal activation or pathological alterations of the vasculature in the affected brain region. Obtaining simultaneous morphological and physiological information of neurovasculature is very challenging due to the acoustic distortions and intense light scattering by the skull and brain. In addition, the size of cerebral vasculature in murine brains spans an extended range from just a few microns up to about a millimeter, all to be recorded in 3D and over an area of several dozens of mm2. Numerous imaging techniques exist that excel at characterizing certain aspects of this complex network but are only capable of providing information on a limited spatiotemporal scale. We present a hybrid ultrasound and dual-wavelength optoacoustic microscope, capable of rapid imaging of murine neurovasculature in-vivo, with high spatial resolution down to 12 μm over a large field of view exceeding 50mm2. The dual wavelength imaging capability allows for the visualization of functional blood parameters through an intact skull while pulse-echo ultrasound biomicroscopy images are captured simultaneously by the same scan head. The flexible hybrid design in combination with fast high-resolution imaging in 3D holds promise for generating better insights into the architecture and function of the neurovascular system.

  8. Pressure Transducer Locations

    Data.gov (United States)

    National Aeronautics and Space Administration — Files are located here, defining the locations of the pressure transducers on the HIRENASD model. These locations also correspond to the locations that analysts...

  9. Eigenspectra optoacoustic tomography achieves quantitative blood oxygenation imaging deep in tissues

    Science.gov (United States)

    Tzoumas, Stratis; Nunes, Antonio; Olefir, Ivan; Stangl, Stefan; Symvoulidis, Panagiotis; Glasl, Sarah; Bayer, Christine; Multhoff, Gabriele; Ntziachristos, Vasilis

    2016-06-01

    Light propagating in tissue attains a spectrum that varies with location due to wavelength-dependent fluence attenuation, an effect that causes spectral corruption. Spectral corruption has limited the quantification accuracy of optical and optoacoustic spectroscopic methods, and impeded the goal of imaging blood oxygen saturation (sO2) deep in tissues; a critical goal for the assessment of oxygenation in physiological processes and disease. Here we describe light fluence in the spectral domain and introduce eigenspectra multispectral optoacoustic tomography (eMSOT) to account for wavelength-dependent light attenuation, and estimate blood sO2 within deep tissue. We validate eMSOT in simulations, phantoms and animal measurements and spatially resolve sO2 in muscle and tumours, validating our measurements with histology data. eMSOT shows substantial sO2 accuracy enhancement over previous optoacoustic methods, potentially serving as a valuable tool for imaging tissue pathophysiology.

  10. Eigenspectra optoacoustic tomography achieves quantitative blood oxygenation imaging deep in tissues

    Science.gov (United States)

    Tzoumas, Stratis; Nunes, Antonio; Olefir, Ivan; Stangl, Stefan; Symvoulidis, Panagiotis; Glasl, Sarah; Bayer, Christine; Multhoff, Gabriele; Ntziachristos, Vasilis

    2016-01-01

    Light propagating in tissue attains a spectrum that varies with location due to wavelength-dependent fluence attenuation, an effect that causes spectral corruption. Spectral corruption has limited the quantification accuracy of optical and optoacoustic spectroscopic methods, and impeded the goal of imaging blood oxygen saturation (sO2) deep in tissues; a critical goal for the assessment of oxygenation in physiological processes and disease. Here we describe light fluence in the spectral domain and introduce eigenspectra multispectral optoacoustic tomography (eMSOT) to account for wavelength-dependent light attenuation, and estimate blood sO2 within deep tissue. We validate eMSOT in simulations, phantoms and animal measurements and spatially resolve sO2 in muscle and tumours, validating our measurements with histology data. eMSOT shows substantial sO2 accuracy enhancement over previous optoacoustic methods, potentially serving as a valuable tool for imaging tissue pathophysiology. PMID:27358000

  11. Controlled bacteria-gold nanorod interactions for enhancement of optoacoustic contrast

    Science.gov (United States)

    Liopo, Anton; Derry, Paul J.; Ermolinsky, Boris; Su, Richard; Conjusteau, André; Ermilov, Sergey; Zubarev, Eugene R.; Oraevsky, Alexander

    2014-03-01

    Gold-based contrast agents, gold nanorod (GNR), were designed for the enhancement of optoacoustic signal. After synthesis, the GNR-CTAB complexes were modified by pegylation (PEG), or replacement of CTAB (cetyl trimethylammonium bromide) with MTAB (16-mercaptohexadecyl trimethylammonium bromide) for coverage of gold nanorods with heparin (GNR-HP). Modified GNR are purified through centrifugation and filtration. GNRCTAB can be used as a model of positively charged gold surface for quantitative optoacoustic sensing in GNRbacteria interactions, whereas GNR-PEG and GNR-HP can be used as negatively charged gold surface models. We studied controlled agglomeration of contrast agents with the bacteria E.Coli and Vibrio Cholerae. For bacterial sensing, the localized plasmon resonance peak shifts as a function of electrostatic binding, which was detected with two different wavelengths through 3D optoacoustic imaging.

  12. Visual Quality Enhancement in Multispectral Optoacoustic Tomography using Active Contour Segmentation Priors

    CERN Document Server

    Mandal, Subhamoy; Razansky, Daniel

    2015-01-01

    Segmentation of biomedical images is essential for studying and characterizing anatomical structures, detection and evaluation of pathological tissues. Segmentation has been further shown to enhance the reconstruction performance in many tomographic imaging modalities by accounting for heterogeneities of the excitation field and tissue properties in the imaged region. This is particularly relevant in optoacoustic tomography, where discontinuities in the optical and acoustic tissue properties, if not properly accounted for, may result in deterioration of the imaging performance. Efficient segmentation of optoacoustic images is often hampered by the relatively low intrinsic contrast of large anatomical structures, which is further impaired by the limited angular coverage of some commonly employed tomographic imaging configurations. Herein, we analyze the performance of active contour models for boundary segmentation in cross-sectional optoacoustic tomography. The segmented mask is employed to construct a two co...

  13. In vivo cryoablation of prostate tissue with temperature monitoring by optoacoustic imaging

    Science.gov (United States)

    Petrova, Elena V.; Motamedi, Massoud; Oraevsky, Alexander A.; Ermilov, Sergey A.

    2016-03-01

    Cryoablation of prostate cancer is an FDA approved clinical procedure, which involves repetitive rapid cooling of a lesion to lethal temperatures of -40°C and below. The major drawback of the technique is the insufficient control over the fast thermal processes that may result in severe complications (impotence, incontinence, perforation of the rectal wall) and morbidity. The developed optoacoustic imaging technique provides non-invasive real-time temperature mapping of tissue adjacent to prostate and enables more efficient control over the procedure, which is necessary to reduce side effects and accelerate the physician's learning curve. In these studies we successfully demonstrated real-time transrectal optoacoustic imaging during prostate cryoablation in live canine model focused on optoacoustic thermography of the rectal wall within the depth of 1cm. Our method utilized previously discovered universal thermal dependence of the normalized optoacoustic response of blood. Nanosecond-pulse radiation of Ti-Sapphire laser tuned to the isosbestic point of hemoglobin (802+/-3 nm) was delivered via fiberoptic illuminators assembled on both sides of the linear array of the 128-channel transrectal ultrasound probe. Temperature readouts at discrete locations inside and nearby prostate were also performed using standard transperineal needle sensors. The effect of homeostasis on optoacoustic imaging in live tissue was examined during cooling and shown to be significant only within the range of +/-1.5°C in respect to the body temperature. Accuracy of in vivo optoacoustic temperature measurements was determined as +/-2°C for the range of temperature from +35 to -15°C, which is more than sufficient for tracking the essential isotherms in the course of clinical procedures.

  14. In vivo optoacoustic monitoring of calcium activity in the brain (Conference Presentation)

    Science.gov (United States)

    Deán-Ben, Xose Luís.; Gottschalk, Sven; Sela, Gali; Lauri, Antonella; Kneipp, Moritz; Ntziachristos, Vasilis; Westmeyer, Gil G.; Shoham, Shy; Razansky, Daniel

    2017-03-01

    Non-invasive observation of spatio-temporal neural activity of large neural populations distributed over the entire brain of complex organisms is a longstanding goal of neuroscience [1,2]. Recently, genetically encoded calcium indicators (GECIs) have revolutionized neuroimaging by enabling mapping the activity of entire neuronal populations in vivo [3]. Visualization of these powerful sensors with fluorescence microscopy has however been limited to superficial regions while deep brain areas have so far remained unreachable [4]. We have developed a volumetric multispectral optoacoustic tomography platform for imaging neural activation deep in scattering brains [5]. The developed methodology can render 100 volumetric frames per second across scalable fields of view ranging between 50-1000 mm3 with respective spatial resolution of 35-150µm. Experiments performed in immobilized and freely swimming larvae and in adult zebrafish brains expressing the genetically-encoded calcium indicator GCaMP5G demonstrated, for the first time, the fundamental ability to directly track neural dynamics using optoacoustics while overcoming the depth barrier of optical imaging in scattering brains [6]. It was further possible to monitor calcium transients in a scattering brain of a living adult transgenic zebrafish expressing GCaMP5G calcium indicator [7]. Fast changes in optoacoustic traces associated to GCaMP5G activity were detectable in the presence of other strongly absorbing endogenous chromophores, such as hemoglobin. The results indicate that the optoacoustic signal traces generally follow the GCaMP5G fluorescence dynamics and further enable overcoming the longstanding optical-diffusion penetration barrier associated to scattering in biological tissues [6]. The new functional optoacoustic neuroimaging method can visualize neural activity at penetration depths and spatio-temporal resolution scales not covered with the existing neuroimaging techniques. Thus, in addition to the well

  15. Influence of the absorber dimensions on wavefront shaping based on volumetric optoacoustic feedback

    CERN Document Server

    Dean-Ben, X L; Ozbek, A; Razansky, D

    2015-01-01

    The recently demonstrated control over light distribution through turbid media based on real-time three-dimensional optoacoustic feedback has offered promising prospects to interferometrically focus light within scattering objects. Nevertheless, the focusing capacity of the feedback-based approach is strongly conditioned by the number of effectively resolvable optical modes (speckles). In this letter, we experimentally tested the light intensity enhancement achieved with optoacoustic feedback measurements from different sizes of absorbing microparticles. The importance of the obtained results is discussed in the context of potential signal enhancement at deep locations within a scattering medium where the effective speckle sizes approach the minimum values dictated by optical diffraction.

  16. A Novel Algorithm of Surface Eliminating in Undersurface Optoacoustic Imaging

    Directory of Open Access Journals (Sweden)

    Zhulina Yulia V

    2004-01-01

    Full Text Available This paper analyzes the task of optoacoustic imaging of the objects located under the surface covering them. In this paper, we suggest the algorithm of the surface eliminating based on the fact that the intensity of the image as a function of the spatial point should change slowly inside the local objects, and will suffer a discontinuity of the spatial gradients on their boundaries. The algorithm forms the 2-dimensional curves along which the discontinuity of the signal derivatives is detected. Then, the algorithm divides the signal space into the areas along these curves. The signals inside the areas with the maximum level of the signal amplitudes and the maximal gradient absolute values on their edges are put equal to zero. The rest of the signals are used for the image restoration. This method permits to reconstruct the picture of the surface boundaries with a higher contrast than that of the surface detection technique based on the maximums of the received signals. This algorithm does not require any prior knowledge of the signals' statistics inside and outside the local objects. It may be used for reconstructing any images with the help of the signals representing the integral over the object's volume. Simulation and real data are also provided to validate the proposed method.

  17. Generation of anatomically realistic numerical phantoms for optoacoustic breast imaging

    Science.gov (United States)

    Lou, Yang; Mitsuhashi, Kenji; Appleton, Catherine M.; Oraevsky, Alexander; Anastasio, Mark A.

    2016-03-01

    Because optoacoustic tomography (OAT) can provide functional information based on hemoglobin contrast, it is a promising imaging modality for breast cancer diagnosis. Developing an effective OAT breast imaging system requires balancing multiple design constraints, which can be expensive and time-consuming. Therefore, computer- simulation studies are often conducted to facilitate this task. However, most existing computer-simulation studies of OAT breast imaging employ simple phantoms such as spheres or cylinders that over-simplify the complex anatomical structures in breasts, thus limiting the value of these studies in guiding real-world system design. In this work, we propose a method to generate realistic numerical breast phantoms for OAT research based on clinical magnetic resonance imaging (MRI) data. The phantoms include a skin layer that defines breast-air boundary, major vessel branches that affect light absorption in the breast, and fatty tissue and fibroglandular tissue whose acoustical heterogeneity perturbs acoustic wave propagation. By assigning realistic optical and acoustic parameters to different tissue types, we establish both optic and acoustic breast phantoms, which will be exported into standard data formats for cross-platform usage.

  18. [Spatial and temporal control of ultrasonic fields via optoacoustic holography].

    Science.gov (United States)

    Gspan, Stefan; Meyer, Alex; Bernet, Stefan; Ritsch-Marte, Monika

    2004-01-01

    The present paper presents a new method for generating ultrasound, based on the interaction of laser-induced ultrasound generation and ultrasonic holography. An ultrasonic field generated in a water tank via the optoacoustic effect is spatially and temporally controlled: In order to produce defined ultrasonic frequencies in the MHz range, the laser pulses incident on a light-absorbing layer are modulated in time using an electro-optic modulator (EOM). Additionally, a high-resolution liquid crystal spatial light modulator (SLM) is used to imprint a pre-calculated phase front to the laser beam. A computer-generated binary hologram is also displayed at the SLM. The expanded laser beam projects the corresponding pattern to the plane absorptive layer in the water tank. The projection of specific patterns for the generation of ultrasonic beams resembles the use of, diffractive optical elements" in optics. Optical ultrasound generation with holographic steering is a flexible tool with promising numerous new applications in medical and technical ultrasound diagnostics.

  19. Konstruktion af transducer

    DEFF Research Database (Denmark)

    Henriksen, Lars; Nielsen, Martin Pram

    Formålet med dette midtvejsprojekt er at udarbejde en transducer til måling af pressers stivhed. Dette er gjort på baggrund af en gennemgang af både presse- og stativ-typer samtidig med at udbøjningssituationen beskrives. Der introduceres en ide, der udgør grundkonceptet for opmålingsproceduren o...... færdige transducer – Load cellen. Strain gauge sørger for dataopsamlingen fra load cellen. Disse kalibreres således at transduceren er klar til de videre målinger der ligger i forlængelse af dette projekt....

  20. Curved PVDF airborne transducer.

    Science.gov (United States)

    Wang, H; Toda, M

    1999-01-01

    In the application of airborne ultrasonic ranging measurement, a partially cylindrical (curved) PVDF transducer can effectively couple ultrasound into the air and generate strong sound pressure. Because of its geometrical features, the ultrasound beam angles of a curved PVDF transducer can be unsymmetrical (i.e., broad horizontally and narrow vertically). This feature is desired in some applications. In this work, a curved PVDF air transducer is investigated both theoretically and experimentally. Two resonances were observed in this transducer. They are length extensional mode and flexural bending mode. Surface vibration profiles of these two modes were measured by a laser vibrometer. It was found from the experiment that the surface vibration was not uniform along the curvature direction for both vibration modes. Theoretical calculations based on a model developed in this work confirmed the experimental results. Two displacement peaks were found in the piezoelectric active direction of PVDF film for the length extensional mode; three peaks were found for the flexural bending mode. The observed peak positions were in good agreement with the calculation results. Transient surface displacement measurements revealed that vibration peaks were in phase for the length extensional mode and out of phase for the flexural bending mode. Therefore, the length extensional mode can generate a stronger ultrasound wave than the flexural bending mode. The resonance frequencies and vibration amplitudes of the two modes strongly depend on the structure parameters as well as the material properties. For the transducer design, the theoretical model developed in this work can be used to optimize the ultrasound performance.

  1. Optoacoustic detection and monitoring of blast-induced intracranial hematomas in rats

    Science.gov (United States)

    Petrov, Andrey; Wynne, Karon E.; Prough, Donald S.; Dewitt, Douglas S.; Petrov, Yuriy; Petrov, Irene Y.; Parsley, Margaret A.; Esenaliev, Rinat O.

    2014-03-01

    Patients with acute intracranial hematomas often require surgical drainage within the first four hours after traumatic brain injury (TBI) to avoid death or severe neurologic disability. CT and MRI permit rapid, noninvasive diagnosis of hematomas, but can be used only at a major health-care facility. At present, there is no device for noninvasive detection and characterization of hematomas in pre-hospital settings. We proposed to use an optoacoustic technique for rapid, noninvasive diagnosis and monitoring of hematomas, including intracranial hematomas. Unlike bulky CT and MR equipment, an optoacoustic system can be small and easily transported in an emergency vehicle. In this study we used a specially-designed blast device to inflict TBI in rats. A near-infrared OPO-based optoacoustic system developed for hematoma diagnosis and for blood oxygenation monitoring in the superior sagittal sinus (SSS) in small animals was used in the study. Optoacoustic signals recorded simultaneously from the SSS and hematomas allowed for measurements of their oxygenations. The presence of hematomas was confirmed after the experiment in gross pictures of the exposed brains. After blast the hematoma signal and oxygenation increased, while SSS oxygenation decreased due to the blastinduced TBI. The increase of the oxygenation in fresh hematomas may be explained by the leakage of blood from arteries which have higher blood pressure compared to that of veins. These results indicate that the optoacoustic technique can be used for early diagnosis of hematomas and may provide important information for improving outcomes in patients with TBI or stroke (both hemorrhagic and ischemic).

  2. Resonant acoustic transducer system for a well drilling string

    Science.gov (United States)

    Kent, William H.; Mitchell, Peter G.

    1981-01-01

    For use in transmitting acoustic waves propagated along a well drilling string, a piezoelectric transducer is provided operating in the relatively low loss acoustic propagation range of the well drilling string. The efficiently coupled transmitting transducer incorporates a mass-spring-piezoelectric transmitter combination permitting resonant operation in the desired low frequency range.

  3. Future needs for biomedical transducers

    Science.gov (United States)

    Wooten, F. T.

    1971-01-01

    In summary there are three major classes of transducer improvements required: improvements in existing transducers, needs for unexploited physical science phenomena in transducer design, and needs for unutilized physiological phenomena in transducer design. During the next decade, increasing emphasis will be placed on noninvasive measurement in all of these areas. Patient safety, patient comfort, and the need for efficient utilization of the time of both patient and physician requires that noninvasive methods of monitoring be developed.

  4. Three dimensional transducer

    Science.gov (United States)

    Warren, Oden Lee; Asif, Syed Amanulla Syed; Oh, Yunje; Feng, Yuxin; Cyrankowski, Edward; Major, Ryan

    2014-09-30

    A testing instrument for mechanical testing at nano or micron scale includes a transducer body, and a coupling shaft coupled with a probe tip. A transducer body houses a capacitor. The capacitor includes first and second counter electrodes and a center electrode assembly interposed therebetween. The center electrode assembly is movable with the coupling shaft relative to the first and second counter electrodes, for instance in one or more of dimensions including laterally and normally. The center electrode assembly includes a center plate coupled with the coupling shaft and one or more springs extending from the center plate. Upper and lower plates are coupled with the center plate and cover the center plate and the one or more springs. A shaft support assembly includes one or more support elements coupled along the coupling shaft. The shaft support assembly provides lateral support to the coupling shaft.

  5. Nano-optomechanical transducer

    Science.gov (United States)

    Rakich, Peter T; El-Kady, Ihab F; Olsson, Roy H; Su, Mehmet Fatih; Reinke, Charles; Camacho, Ryan; Wang, Zheng; Davids, Paul

    2013-12-03

    A nano-optomechanical transducer provides ultrabroadband coherent optomechanical transduction based on Mach-wave emission that uses enhanced photon-phonon coupling efficiencies by low impedance effective phononic medium, both electrostriction and radiation pressure to boost and tailor optomechanical forces, and highly dispersive electromagnetic modes that amplify both electrostriction and radiation pressure. The optomechanical transducer provides a large operating bandwidth and high efficiency while simultaneously having a small size and minimal power consumption, enabling a host of transformative phonon and signal processing capabilities. These capabilities include optomechanical transduction via pulsed phonon emission and up-conversion, broadband stimulated phonon emission and amplification, picosecond pulsed phonon lasers, broadband phononic modulators, and ultrahigh bandwidth true time delay and signal processing technologies.

  6. Three dimensional transducer

    Energy Technology Data Exchange (ETDEWEB)

    Warren, Oden Lee; Asif, Syed Amanulla Syed; Oh, Yunje; Feng, Yuxin; Cyrankowski, Edward; Major, Ryan

    2014-09-30

    A testing instrument for mechanical testing at nano or micron scale includes a transducer body, and a coupling shaft coupled with a probe tip. A transducer body houses a capacitor. The capacitor includes first and second counter electrodes and a center electrode assembly interposed therebetween. The center electrode assembly is movable with the coupling shaft relative to the first and second counter electrodes, for instance in one or more of dimensions including laterally and normally. The center electrode assembly includes a center plate coupled with the coupling shaft and one or more springs extending from the center plate. Upper and lower plates are coupled with the center plate and cover the center plate and the one or more springs. A shaft support assembly includes one or more support elements coupled along the coupling shaft. The shaft support assembly provides lateral support to the coupling shaft.

  7. Polymer Optical Fibre Sensors for Endoscopic Opto-Acoustic Imaging

    DEFF Research Database (Denmark)

    Broadway, Christian; Gallego, Daniel; Woyessa, Getinet;

    2015-01-01

    in existing publications. A great advantage can be obtained for endoscopy due to a small size and array potential to provide discrete imaging speed improvements. Optical fibre exhibits numerous advantages over conventional piezo-electric transducers, such as immunity from electromagnetic interference...

  8. Numerical transducer modelling

    DEFF Research Database (Denmark)

    Cutanda, Vicente

    1999-01-01

    Numerical modelling is of importance for the design, improvement and study of acoustic transducers such as microphones and accelerometers. Techniques like the boundary element method and the finite element method are the most common supplement to the traditional empirical and analytical approaches...... errors and instabilities in the computations of numerical solutions. An investigation to deal with this narrow-gap problem has been carried out....

  9. Stress wave focusing transducers

    Energy Technology Data Exchange (ETDEWEB)

    Visuri, S.R., LLNL

    1998-05-15

    Conversion of laser radiation to mechanical energy is the fundamental process behind many medical laser procedures, particularly those involving tissue destruction and removal. Stress waves can be generated with laser radiation in several ways: creation of a plasma and subsequent launch of a shock wave, thermoelastic expansion of the target tissue, vapor bubble collapse, and ablation recoil. Thermoelastic generation of stress waves generally requires short laser pulse durations and high energy density. Thermoelastic stress waves can be formed when the laser pulse duration is shorter than the acoustic transit time of the material: {tau}{sub c} = d/c{sub s} where d = absorption depth or spot diameter, whichever is smaller, and c{sub s} = sound speed in the material. The stress wave due to thermoelastic expansion travels at the sound speed (approximately 1500 m/s in tissue) and leaves the site of irradiation well before subsequent thermal events can be initiated. These stress waves, often evolving into shock waves, can be used to disrupt tissue. Shock waves are used in ophthalmology to perform intraocular microsurgery and photodisruptive procedures as well as in lithotripsy to fragment stones. We have explored a variety of transducers that can efficiently convert optical to mechanical energy. One such class of transducers allows a shock wave to be focused within a material such that the stress magnitude can be greatly increased compared to conventional geometries. Some transducer tips could be made to operate regardless of the absorption properties of the ambient media. The size and nature of the devices enable easy delivery, potentially minimally-invasive procedures, and precise tissue- targeting while limiting thermal loading. The transducer tips may have applications in lithotripsy, ophthalmology, drug delivery, and cardiology.

  10. Frequency steerable acoustic transducers

    Science.gov (United States)

    Senesi, Matteo

    Structural health monitoring (SHM) is an active research area devoted to the assessment of the structural integrity of critical components of aerospace, civil and mechanical systems. Guided wave methods have been proposed for SHM of plate-like structures using permanently attached piezoelectric transducers, which generate and sense waves to evaluate the presence of damage. Effective interrogation of structural health is often facilitated by sensors and actuators with the ability to perform electronic, i.e. phased array, scanning. The objective of this research is to design an innovative directional piezoelectric transducer to be employed for the localization of broadband acoustic events, or for the generation of Lamb waves for active interrogation of structural health. The proposed Frequency Steerable Acoustic Transducers (FSATs) are characterized by a spatial arrangement of active material which leads to directional characteristics varying with frequency. Thus FSATs can be employed both for directional sensing and generation of guided waves without relying on phasing and control of a large number of channels. The analytical expression of the shape of the FSATs is obtained through a theoretical formulation for continuously distributed active material as part of a shaped piezoelectric device. The FSAT configurations analyzed in this work are a quadrilateral array and a geometry which corresponds to a spiral in the wavenumber domain. The quadrilateral array is experimentally validated, confirming the concept of frequency-dependent directionality. Its limited directivity is improved by the Wavenumber Spiral FSAT (WS-FSAT), which, instead, is characterized by a continuous frequency dependent directionality. Preliminary validations of the WS-FSAT, using a laser doppler vibrometer, are followed by the implementation of the WS-FSAT as a properly shaped piezo transducer. The prototype is first used for localization of acoustic broadband sources. Signal processing

  11. Fluid force transducer

    Science.gov (United States)

    Jendrzejczyk, Joseph A.

    1982-01-01

    An electrical fluid force transducer for measuring the magnitude and direction of fluid forces caused by lateral fluid flow, includes a movable sleeve which is deflectable in response to the movement of fluid, and a rod fixed to the sleeve to translate forces applied to the sleeve to strain gauges attached to the rod, the strain gauges being connected in a bridge circuit arrangement enabling generation of a signal output indicative of the magnitude and direction of the force applied to the sleeve.

  12. Polymer film composite transducer

    Science.gov (United States)

    Owen, Thomas E.

    2005-09-20

    A composite piezoelectric transducer, whose piezoeletric element is a "ribbon wound" film of piezolectric material. As the film is excited, it expands and contracts, which results in expansion and contraction of the diameter of the entire ribbon winding. This is accompanied by expansion and contraction of the thickness of the ribbon winding, such that the sound radiating plate may be placed on the side of the winding.

  13. Steerable Doppler transducer probes

    Energy Technology Data Exchange (ETDEWEB)

    Fidel, H.F.; Greenwood, D.L.

    1986-07-22

    An ultrasonic diagnostic probe is described which is capable of performing ultrasonic imaging and Doppler measurement consisting of: a hollow case having an acoustic window which passes ultrasonic energy and including chamber means for containing fluid located within the hollow case and adjacent to a portion of the acoustic window; imaging transducer means, located in the hollow case and outside the fluid chamber means, and oriented to direct ultrasonic energy through the acoustic window toward an area which is to be imaged; Doppler transducer means, located in the hollow case within the fluid chamber means, and movably oriented to direct Doppler signals through the acoustic window toward the imaged area; means located within the fluid chamber means and externally controlled for controllably moving the Doppler transducer means to select one of a plurality of axes in the imaged area along which the Doppler signals are to be directed; and means, located external to the fluid chamber means and responsive to the means for moving, for providing an indication signal for identifying the selected axis.

  14. Transducers for ultrasonic limb plethysmography

    Science.gov (United States)

    Nickell, W. T.; Wu, V. C.; Bhagat, P. K.

    1983-01-01

    The design, construction, and performance characteristics of ultasonic transducers suitable for limb plethysmography are presented. Both 3-mm-diameter flat-plate and 12-mm-diameter hemispheric ceramic transducers operating at 2 MHz were fitted in 1-mm thick epoxy-resin lens/acoustic-coupling structures and mounted in exercie-EKG electrode housings for placement on the calf using adhesive collars. The effects of transducer directional characteristics on performance under off-axis rotation and the electrical impedances of the transducers were measured: The flat transducer was found to be sensitive to rotation and have an impedance of 800 ohms; the hemispheric transducer, to be unaffected by rotation and have an impedance of 80 ohms. The use of hemispheric transducers as both transmitter and receiver, or of a flat transducer as transmitter and a hemispheric transducer as receiver, was found to produce adequate dimensional measurements, with minimum care in transducer placement, in short-term physiological experiments and long-term (up to 7-day) attachment tests.

  15. Piezoelectric transducer array microspeaker

    KAUST Repository

    Carreno, Armando Arpys Arevalo

    2016-12-19

    In this paper we present the fabrication and characterization of a piezoelectric micro-speaker. The speaker is an array of micro-machined piezoelectric membranes, fabricated on silicon wafer using advanced micro-machining techniques. Each array contains 2n piezoelectric transducer membranes, where “n” is the bit number. Every element of the array has a circular shape structure. The membrane is made out four layers: 300nm of platinum for the bottom electrode, 250nm or lead zirconate titanate (PZT), a top electrode of 300nm and a structural layer of 50

  16. Numerical transducer modelling

    DEFF Research Database (Denmark)

    Cutanda, Vicente

    1999-01-01

    Numerical modelling is of importance for the design, improvement and study of acoustic transducers such as microphones and accelerometers. Techniques like the boundary element method and the finite element method are the most common supplement to the traditional empirical and analytical approaches....... However, there are several difficulties to be addressed that are derived from the size, internal structure and precision requirements that are characteristic of these devices. One of them, the presence of very close surfaces (e.g. the microphone diaphragm and back-electrode), leads to machine precision...

  17. Wellbore pressure transducer

    Science.gov (United States)

    Shuck, Lowell Z.

    1979-01-01

    Subterranean earth formations containing energy values are subjected to hydraulic fracturing procedures to enhance the recovery of the energy values. These fractures are induced in the earth formation by pumping liquid into the wellbore penetrating the earth formation until the pressure of the liquid is sufficient to fracture the earth formation adjacent to the wellbore. The present invention is directed to a transducer which is positionable within the wellbore to generate a signal indicative of the fracture initiation useful for providing a timing signal to equipment for seismic mapping of the fracture as it occurs and for providing a measurement of the pressure at which the fracture is initiated.

  18. RADIO-ACTIVE TRANSDUCER

    Science.gov (United States)

    Wanetick, S.

    1962-03-01

    ABS>ure the change in velocity of a moving object. The transducer includes a radioactive source having a collimated beam of radioactive particles, a shield which can block the passage of the radioactive beam, and a scintillation detector to measure the number of radioactive particles in the beam which are not blocked by the shield. The shield is operatively placed across the radioactive beam so that any motion normal to the beam will cause the shield to move in the opposite direction thereby allowing more radioactive particles to reach the detector. The number of particles detected indicates the acceleration. (AEC)

  19. Small animal optoacoustic tomography system for molecular imaging of contrast agents

    Science.gov (United States)

    Su, Richard; Liopo, Anton; Ermilov, Sergey A.; Oraevsky, Alexander A.

    2016-03-01

    We developed a new and improved Laser Optoacoustic Imaging System, LOIS-3D for preclinical research applications in small animal models. The advancements include (i) a new stabilized imaging module with a more homogeneous illumination of the mouse yielding a better spatial resolution (research applications, such as imaging vascularization and measuring hemoglobin / oxyhemoglobin distribution in the organs as well as imaging exogenous or endogenous optoacoustic contrast agents. As examples, we present in vivo experiments using phantoms and mice with and without tumor injected with contrast agents with indocyanine green (ICG). LOIS-3D was capable of detecting ~1-2 pmole of the ICG, in tissues with relatively low blood content. With its high sensitivity and excellent spatial resolution LOIS-3D is an advanced alternative to fluorescence and bioluminescence based modalities for molecular imaging in live mice.

  20. Transducer of linear displacements

    Science.gov (United States)

    Malamed, Y. R.

    1984-02-01

    The basic PLP transducer is designed for a UIM-29 microscope and a 2-coordinate measuring instrument with electronic digital readout. Its optical system consists of an AL-107B light-emitting diode as light source, two condenser lenses, a special wedge carrying two pairs of joined receiver lenses, a prism-mirror, a photoreceiver, a wedge-shape transparent replica of a twin diffraction grating which prevents light reflected by the air-glass interface from focusing on the receiver photodiodes, and a reflective replica of a diffraction grating on a movable carriage. The already available three models of this transducer are PLP1-0.2, PLP1-0.5, and PLP1-1.0 with respectively 625, 250, 125 lines/mm on the transparent replica and respectively 312.5, 125, 62.5 lines/mm on the reflective replica. The scale of moire-interference fringes characterizing the shift between both diffraction gratings per grating period (9.16 mm in each model) is respectively 0.8, 2.0, 4.0 microns and the angle between the two arrays of grating lines on the transparent replica is respectively 36 + or - 4 deg, 90 + or - 10 deg, 190 + or - 20 deg.

  1. Fabry-Perot micro-structured polymer optical fibre sensors for opto-acoustic endoscopy

    DEFF Research Database (Denmark)

    Broadway, Christian; Gallego, Daniel; Woyessa, Getinet;

    2015-01-01

    Opto-Acoustic Endoscopy (OAE) requires sensors with a high sensitivity and small physical dimensions in order to facilitate integration into an endoscope of less than 1mm in diameter. We present fibre Bragg grating (FBG) and Fabry- Perot intrinsic fibre sensors for ultrasound detection. We presen...... and a simplification of the detection regime for an optimal interferometric OAE configuration. © (2015) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only....

  2. Superconducting Qubit Optical Transducer (SQOT)

    Science.gov (United States)

    2015-08-05

    SECURITY CLASSIFICATION OF: The SQOT (Superconducting Qubit Optical Transducer ) project proposes to build a novel electro-optic system which can...Apr-2015 Approved for Public Release; Distribution Unlimited Final Report: "Superconducting Qubit Optical Transducer " (SQOT) The views, opinions and...journals: Number of Papers published in non peer-reviewed journals: Final Report: "Superconducting Qubit Optical Transducer " (SQOT) Report Title The

  3. Calibration of Field II using a Convex Ultrasound Transducer

    DEFF Research Database (Denmark)

    Bæk, David; Jensen, Jørgen Arendt; Willatzen, Morten

    2010-01-01

    Field II is an ultrasound simulation program capable of simulating the pressure scattering from inhomogeneous tissue. The simulations are based on a convolution between spatial impulse responses from the field in front of the transducer and the volt-to-surface acceleration impulse response...... of the transducer. For such simulations to reflect actual measured intensities and pressure levels, the transducer impulse response is to be known. This work presents the results of combining a modified form of a 1D linear transducer model originally suggested by Willatzen with the Field II program to calibrate...... BK-Medical (Herlev, Denmark). As input waveform for the Field model we measured the output voltage of the research amplifier, which peak voltage was limited to 31 V to avoid too high non linear effects. We measured the hydrophone output from three transducer front elements by averaging 40 shoot...

  4. Novel optoacoustic system for noninvasive continuous monitoring of cerebral venous blood oxygenation

    Science.gov (United States)

    Petrov, Yuriy; Petrov, Irene Y.; Prough, Donald S.; Esenaliev, Rinat O.

    2012-02-01

    Traumatic brain injury (TBI) and spinal cord injury are a major cause of death for individuals under 50 years of age. In the USA alone, 150,000 patients per year suffer moderate or severe TBI. Moreover, TBI is a major cause of combatrelated death. Monitoring of cerebral venous blood oxygenation is critically important for management of TBI patients because cerebral venous blood oxygenation below 50% results in death or severe neurologic complications. At present, there is no technique for noninvasive, accurate monitoring of this clinically important variable. We proposed to use optoacoustic technique for noninvasive monitoring of cerebral venous blood oxygenation by probing cerebral veins such as the superior sagittal sinus (SSS) and validated it in animal studies. In this work, we developed a novel, medical grade optoacoustic system for continuous, real-time cerebral venous blood oxygenation monitoring and tested it in human subjects at normal conditions and during hyperventilation to simulate changes that may occur in patients with TBI. We designed and built a highly-sensitive optoacoustic probe for SSS signal detection. Continuous measurements were performed in the near infrared spectral range and the SSS oxygenation absolute values were automatically calculated in real time using a special algorithm developed by our group. Continuous measurements performed at normal conditions and during hyperventilation demonstrated that hyperventilation resulted in approximately 12% decrease of cerebral venous blood oxygenation.

  5. Opto-Acoustic Data Fusion for Supporting the Guidance of Remotely Operated Underwater Vehicles (ROVs)

    Science.gov (United States)

    Bruno, F.; Lagudi, A.; Ritacco, G.; Muzzupappa, M.; Guida, R.

    2015-04-01

    Remotely Operated underwater Vehicles (ROVs) play an important role in a number of operations conducted in shallow and deep water (e.g.: exploration, survey, intervention, etc.), in several application fields like marine science, offshore construction, and underwater archeology. ROVs are usually equipped with different imaging devices, both optical and acoustic. Optical sensors are able to generate better images in close range and clear water conditions, while acoustic systems are usually employed in long range acquisitions and do not suffer from the presence of turbidity, a well-known cause of coarser resolution and harder data extraction. In this work we describe the preliminary steps in the development of an opto-acoustic camera able to provide an on-line 3D reconstruction of the acquired scene. Taking full advantage of the benefits arising from the opto-acoustic data fusion techniques, the system was conceived as a support tool for ROV operators during the navigation in turbid waters, or in operations conducted by means of mechanical manipulators. The paper presents an overview of the device, an ad-hoc methodology for the extrinsic calibration of the system and a custom software developed to control the opto-acoustic camera and supply the operator with visual information.

  6. Unmixing chromophores in human skin with a 3D multispectral optoacoustic mesoscopy system

    Science.gov (United States)

    Schwarz, Mathias; Aguirre, Juan; Soliman, Dominik; Buehler, Andreas; Ntziachristos, Vasilis

    2016-03-01

    The absorption of visible light by human skin is governed by a number of natural chromophores: Eumelanin, pheomelanin, oxyhemoglobin, and deoxyhemoglobin are the major absorbers in the visible range in cutaneous tissue. Label-free quantification of these tissue chromophores is an important step of optoacoustic (photoacoustic) imaging towards clinical application, since it provides relevant information in diseases. In tumor cells, for instance, there are metabolic changes (Warburg effect) compared to healthy cells, leading to changes in oxygenation in the environment of tumors. In malignant melanoma changes in the absorption spectrum have been observed compared to the spectrum of nonmalignant nevi. So far, optoacoustic imaging has been applied to human skin mostly in single-wavelength mode, providing anatomical information but no functional information. In this work, we excited the tissue by a tunable laser source in the spectral range from 413-680 nm with a repetition rate of 50 Hz. The laser was operated in wavelengthsweep mode emitting consecutive pulses at various wavelengths that allowed for automatic co-registration of the multispectral datasets. The multispectral raster-scan optoacoustic mesoscopy (MSOM) system provides a lateral resolution of <60 μm independent of wavelength. Based on the known absorption spectra of melanin, oxyhemoglobin, and deoxyhemoglobin, three-dimensional absorption maps of all three absorbers were calculated from the multispectral dataset.

  7. Numerical Transducer Modeling

    DEFF Research Database (Denmark)

    Henriquez, Vicente Cutanda

    This thesis describes the development of a numerical model of the propagation of sound waves in fluids with viscous and thermal losses, with application to the simulation of acoustic transducers, in particular condenser microphones for measurement. The theoretical basis is presented, numerical...... tools and implementation techniques are described and performance tests are carried out. The equations that govern the motion of fluids with losses and the corresponding boundary conditions are reduced to a form that is tractable for the Boundary Element Method (BEM) by adopting some hypotheses...... that are allowable in this case: linear variations, absence of flow, harmonic time variation, thermodynamical equilibrium and physical dimensions much larger than the molecular mean free path. A formulation of the BEM is also developed with an improvement designed to cope with the numerical difficulty associated...

  8. Optically transduced MEMS magnetometer

    Science.gov (United States)

    Nielson, Gregory N; Langlois, Eric

    2014-03-18

    MEMS magnetometers with optically transduced resonator displacement are described herein. Improved sensitivity, crosstalk reduction, and extended dynamic range may be achieved with devices including a deflectable resonator suspended from the support, a first grating extending from the support and disposed over the resonator, a pair of drive electrodes to drive an alternating current through the resonator, and a second grating in the resonator overlapping the first grating to form a multi-layer grating having apertures that vary dimensionally in response to deflection occurring as the resonator mechanically resonates in a plane parallel to the first grating in the presence of a magnetic field as a function of the Lorentz force resulting from the alternating current. A plurality of such multi-layer gratings may be disposed across a length of the resonator to provide greater dynamic range and/or accommodate fabrication tolerances.

  9. Electromagnetic acoustic transducer

    Science.gov (United States)

    Alers, George A.; Burns, Jr., Leigh R.; MacLauchlan, Daniel T.

    1988-01-01

    A noncontact ultrasonic transducer for studying the acoustic properties of a metal workpiece includes a generally planar magnetizing coil positioned above the surface of the workpiece, and a generally planar eddy current coil between the magnetizing coil and the workpiece. When a large current is passed through the magnetizing coil, a large magnetic field is applied to the near-surface regions of the workpiece. The eddy current coil can then be operated as a transmitter by passing an alternating current therethrough to excite ultrasonic waves in the surface of the workpiece, or operated as a passive receiver to sense ultrasonic waves in the surface by measuring the output signal. The geometries of the two coils can be varied widely to be effective for different types of ultrasonic waves. The coils are preferably packaged in a housing which does not interfere with their operation, but protects them from a variety of adverse environmental conditions.

  10. Parameter sensitivity study of a Field II multilayer transducer model on a convex transducer

    DEFF Research Database (Denmark)

    Bæk, David; Jensen, Jørgen Arendt; Willatzen, Morten

    2009-01-01

    .ResultsPredictions using the ZR give a pressure pulse error (PPE) and an intensity error (IE) of 32 % and 23 %, respectively, relative to the measured. Altering the piezoelectric permittivity +12 % from ZR decreases the PPE to 30 % and the IE to 2 % relative to the measured. Changing the stiffness constant of the lens -4......A multilayer transducer model for predicting a transducer impulse response has in earlier works been developed and combined with the Field II software. This development was tested on current, voltage, and intensity measurements on piezoceramics discs (Bæk et al. IUS 2008) and a convex 128 element...... ultrasound imaging transducer (Bæk et al. ICU 2009). The model benefits from its 1D simplicity and hasshown to give an amplitude error around 1.7‐2 dB. However, any prediction of amplitude, phase, and attenuation of pulses relies on the accuracy of manufacturer supplied material characteristics, which may...

  11. Calibration of Underwater Sound Transducers

    Directory of Open Access Journals (Sweden)

    H.R.S. Sastry

    1983-07-01

    Full Text Available The techniques of calibration of underwater sound transducers for farfield, near-field and closed environment conditions are reviewed in this paper .The design of acoustic calibration tank is mentioned. The facilities available at Naval Physical & Oceanographic Laboratory, Cochin for calibration of transducers are also listed.

  12. On a New Optical Transducer

    Directory of Open Access Journals (Sweden)

    Cornel Bit

    2015-07-01

    Full Text Available This paper presents a new type of mechano – optical force transducer which to be used in different mechanical experimental investigations. This transducer has been integrated within a mechanical modulus, providing a useful tool for this kind of measurements. The use of optical methods for the elastic contact measurements has several important advantages.

  13. Combined Digital Electronic Current and Voltage Transducer

    Institute of Scientific and Technical Information of China (English)

    段雄英; 邹积岩; 等

    2002-01-01

    A high-performance current and voltage measurement system has been developed in power system.The system is composed of two parts:one current measurement element and one voltage measurement element.A Rogowski coil and a capacitive voltage divider are used respectively for the line current and voltage measurements.Active electronic components are used to modulate signal,and power supply for these components is drawn from power line via an auxiliary current transformer,Measurement signal is transmitted y optical fibers,which is resistant to electromagnetic induction and noise,With careful design and the use of digital signal processing technology,the whole system can meet 0.5% accuracy for metering and provides large dynamic range coupled with good accuracy for protective relaying use.

  14. Enhanced C-band Coaxial Orthomode Transducer

    Directory of Open Access Journals (Sweden)

    S. I. Piltyay

    2014-09-01

    Full Text Available Introduction. In this paper a novel configuration of wideband coherent coaxial OMT is presented. General Design of an Orthomode Transducer. The OMT consists of elements of 3 main types: a turnstile junction between coaxial quad-ridged waveguide and 4 coaxial transmission lines; 4 coaxial transmission lines of LMR400 type; 2 antiphase power combiners/dividers. A Turnstile Junction Optimization. The optimization of a turnstile junction has been performed. Its minimized reflection coefficient is less than −28 dB in the operation frequency band 3.4–5.4 GHz. A Wideband Antiphase Power Combiner/Divider. The optimization of an antiphase power combiner/divider has been performed. Its minimized reflection coefficient is less than −38 dB. Characteristics of Coaxial Orthomode Transducer Developed. The simulation of OMT characteristics has been performed using CST Design Studio software. Conclusions. A wideband coherent coaxial orthomode transducer has been developed for the operation frequency band 3.4–5.4 GHz. In this frequency band the reflection coefficient of OMT is less than −24 dB and its crosspolar isolation exceeds 38 dB. The wideband coaxial OMT developed can be used in dual-polarized multiband antennas for satellite telecommunications and for radioastronomy.

  15. Evolvable Cryogenics (ECRYO) Pressure Transducer Calibration Test

    Science.gov (United States)

    Diaz, Carlos E., Jr.

    2015-01-01

    This paper provides a summary of the findings of recent activities conducted by Marshall Space Flight Center's (MSFC) In-Space Propulsion Branch and MSFC's Metrology and Calibration Lab to assess the performance of current "state of the art" pressure transducers for use in long duration storage and transfer of cryogenic propellants. A brief historical narrative in this paper describes the Evolvable Cryogenics program and the relevance of these activities to the program. This paper also provides a review of three separate test activities performed throughout this effort, including: (1) the calibration of several pressure transducer designs in a liquid nitrogen cryogenic environmental chamber, (2) the calibration of a pressure transducer in a liquid helium Dewar, and (3) the calibration of several pressure transducers at temperatures ranging from 20 to 70 degrees Kelvin (K) using a "cryostat" environmental chamber. These three separate test activities allowed for study of the sensors along a temperature range from 4 to 300 K. The combined data shows that both the slope and intercept of the sensor's calibration curve vary as a function of temperature. This homogeneous function is contrary to the linearly decreasing relationship assumed at the start of this investigation. Consequently, the data demonstrates the need for lookup tables to change the slope and intercept used by any data acquisition system. This ultimately would allow for more accurate pressure measurements at the desired temperature range. This paper concludes with a review of a request for information (RFI) survey conducted amongst different suppliers to determine the availability of current "state of the art" flight-qualified pressure transducers. The survey identifies requirements that are most difficult for the suppliers to meet, most notably the capability to validate the sensor's performance at temperatures below 70 K.

  16. Simultaneous control of volumetric light distribution through turbid media using real-time three-dimensional optoacoustic feedback

    CERN Document Server

    Deán-Ben, X Luís; Razansky, Daniel

    2014-01-01

    Focusing light through turbid media presents a highly fascinating challenge in modern biophotonics. The unique capability of optoacoustics for high resolution imaging of light absorption contrast in deep tissues can provide a natural and efficient feedback to control light delivery in scattering medium. While basic feasibility of using optoacoustic readings as a feedback mechanism for wavefront shaping has been recently reported, the suggested approaches may require long acquisition times making them challenging to be translated into realistic tissue environments. In an attempt to significantly accelerate dynamic wavefront shaping capabilities, we present here a feedback-based approach using real-time three-dimensional optoacoustic imaging assisted with genetic-algorithm-based optimization. The new technique offers robust performance in the presence of noisy measurements and can simultaneously control the scattered wave field in an entire volumetric region.

  17. Glass-windowed ultrasound transducers.

    Science.gov (United States)

    Yddal, Tostein; Gilja, Odd Helge; Cochran, Sandy; Postema, Michiel; Kotopoulis, Spiros

    2016-05-01

    In research and industrial processes, it is increasingly common practice to combine multiple measurement modalities. Nevertheless, experimental tools that allow the co-linear combination of optical and ultrasonic transmission have rarely been reported. The aim of this study was to develop and characterise a water-matched ultrasound transducer architecture using standard components, with a central optical window larger than 10 mm in diameter allowing for optical transmission. The window can be used to place illumination or imaging apparatus such as light guides, miniature cameras, or microscope objectives, simplifying experimental setups. Four design variations of a basic architecture were fabricated and characterised with the objective to assess whether the variations influence the acoustic output. The basic architecture consisted of a piezoelectric ring and a glass disc, with an aluminium casing. The designs differed in piezoelectric element dimensions: inner diameter, ID=10 mm, outer diameter, OD=25 mm, thickness, TH=4 mm or ID=20 mm, OD=40 mm, TH=5 mm; glass disc dimensions OD=20-50 mm, TH=2-4 mm; and details of assembly. The transducers' frequency responses were characterised using electrical impedance spectroscopy and pulse-echo measurements, the acoustic propagation pattern using acoustic pressure field scans, the acoustic power output using radiation force balance measurements, and the acoustic pressure using a needle hydrophone. Depending on the design and piezoelectric element dimensions, the resonance frequency was in the range 350-630 kHz, the -6 dB bandwidth was in the range 87-97%, acoustic output power exceeded 1 W, and acoustic pressure exceeded 1 MPa peak-to-peak. 3D stress simulations were performed to predict the isostatic pressure required to induce material failure and 4D acoustic simulations. The pressure simulations indicated that specific design variations could sustain isostatic pressures up to 4.8 MPa.The acoustic simulations were able to

  18. Polymer Optical Fibre Sensors for Endoscopic Opto-Acoustic Imaging

    DEFF Research Database (Denmark)

    Broadway, Christian; Gallego, Daniel; Woyessa, Getinet

    2015-01-01

    is the physical size of the device, allowing compatibility with current technology, while governing flexibility of the distal end of the endoscope based on the needs of the sensor. Polymer optical fibre (POF) presents a novel approach for endoscopic applications and has been positively discussed and compared...... in existing publications. A great advantage can be obtained for endoscopy due to a small size and array potential to provide discrete imaging speed improvements. Optical fibre exhibits numerous advantages over conventional piezo-electric transducers, such as immunity from electromagnetic interference...... and a higher resolution at small sizes. Furthermore, micro structured polymer optical fibres offer over 12 times the sensitivity of silica fibre. We present a polymer fibre Bragg grating ultrasound detector with a core diameter of 125 microns. We discuss the ultrasonic signals received and draw conclusions...

  19. Passive wireless ultrasonic transducer systems

    Science.gov (United States)

    Zhong, C. H.; Croxford, A. J.; Wilcox, P. D.

    2014-02-01

    Inductive coupling and capacitive coupling both offer simple solutions to wirelessly probe ultrasonic transducers. This paper investigates the theory and feasibility of such system in the context of non-destructive evaluation (NDE) applications. Firstly, the physical principles and construction of an inductively coupled transducer system (ICTS) and a capacitively coupled transducer system (CCTS) are introduced. Then the development of a transmission line model with the measured impedance of a bonded piezoelectric ceramic disc representing a sensor attached to an arbitrary solid substrate for both systems is described. The models are validated experimentally. Several applications of CCTS are presented, such CCTS for the underwater and through-composite testing.

  20. Frequency Steered Acoustic Transducer Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This Small Business Innovation Research Phase II project is to fabricate, characterize, and verify performance of a new type of frequency steered acoustic transducer...

  1. An enzyme logic bioprotonic transducer

    Science.gov (United States)

    Miyake, Takeo; Josberger, Erik E.; Keene, Scott; Deng, Yingxin; Rolandi, Marco

    2015-01-01

    Translating ionic currents into measureable electronic signals is essential for the integration of bioelectronic devices with biological systems. We demonstrate the use of a Pd/PdHx electrode as a bioprotonic transducer that connects H+ currents in solution into an electronic signal. This transducer exploits the reversible formation of PdHx in solution according to PdH↔Pd + H+ + e-, and the dependence of this formation on solution pH and applied potential. We integrate the protonic transducer with glucose dehydrogenase as an enzymatic and gate for glucose and NAD+. PdHx formation and associated electronic current monitors the output drop in pH, thus transducing a biological function into a measurable electronic output.

  2. Laboratories practice to transducers study

    Directory of Open Access Journals (Sweden)

    Kleber Romero Felizardo

    2004-01-01

    Full Text Available The objective of this work was to gather a collection of practical laboratory experiences , to discover the physical principles of different types of electrical transducers , and to compare them with theoretical models.

  3. Fixture for holding testing transducer

    Science.gov (United States)

    Wagner, Thomas A.; Engel, Herbert P.

    1984-01-01

    A fixture for mounting an ultrasonic transducer against the end of a threaded bolt or stud to test the same for flaws. A base means threadedly secured to the side of the bolt has a rotating ring thereon. A post rising up from the ring (parallel to the axis of the workpiece) pivotally mounts a variable length cross arm, on the inner end of which is mounted the transducer. A spring means acts between the cross arm and the base to apply the testing transducer against the workpiece at a constant pressure. The device maintains constant for successive tests the radial and circumferential positions of the testing transducer and its contact pressure against the end of the workpiece.

  4. Frequency Steered Acoustic Transducer Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This Small Business Innovation Research Phase I project is to develop, fabricate, and characterize a novel frequency steered acoustic transducer (FSAT) for the...

  5. Transducer Field Imaging Using Acoustography

    Directory of Open Access Journals (Sweden)

    Jaswinder S. Sandhu

    2012-01-01

    Full Text Available A common current practice for transducer field mapping is to scan, point-by-point, a hydrophone element in a 2D raster at various distances from the transducer radiating surface. This approach is tedious, requiring hours of scanning time to generate full cross-sectional and/or axial field distributions. Moreover, the lateral resolution of the field distribution image is dependent on the indexing steps between data points. Acoustography is an imaging process in which an acousto-optical (AO area sensor is employed to record the intensity of an ultrasound wavefield on a two-dimensional plane. This paper reports on the application of acoustography as a simple but practical method for assessing transducer field characteristics. A case study performed on a commercial transducer is reported, where the radiated fields are imaged using acoustography and compared to the corresponding quantities that are predicted numerically.

  6. Acoustic transducer with damping means

    Science.gov (United States)

    Smith, Richard W.; Adamson, Gerald E.

    1976-11-02

    An ultrasonic transducer specifically suited to high temperature sodium applications is described. A piezoelectric active element is joined to the transducer faceplate by coating the faceplate and juxtaposed active element face with wetting agents specifically compatible with the bonding procedure employed to achieve the joint. The opposite face of the active element is fitted with a backing member designed to assure continued electrical continuity during adverse operating conditions which can result in the fracturing of the active element. The fit is achieved employing a spring-loaded electrode operably arranged to electrically couple the internal transducer components, enclosed in a hermetically sealed housing, to accessory components normally employed in transducer applications. Two alternative backing members are taught for assuring electrical continuity. The first employs a resilient, discrete multipoint contact electrode in electrical communication with the active element face. The second employs a resilient, elastomeric, electrically conductive, damped member in electrical communication with the active element face in a manner to effect ring-down of the transducer. Each embodiment provides continued electrical continuity within the transducer in the event the active element fractures, while the second provides the added benefit of damping.

  7. Optoacoustic imaging of tissue blanching during photodynamic therapy of esophageal cancer

    Science.gov (United States)

    Jacques, Steven L.; Viator, John A.; Paltauf, Guenther

    2000-05-01

    Esophageal cancer patients often present a highly inflamed esophagus at the time of treatment by photodynamic therapy. Immediately after treatment, the inflamed vessels have been shut down and the esophagus presents a white surface. Optoacoustic imaging via an optical fiber device can provide a depth profile of the blanching of inflammation. Such a profile may be an indicator of the depth of treatment achieved by the PDT. Our progress toward developing this diagnostic for use in our clinical PDT treatments of esophageal cancer patients is presented.

  8. Interferometric microstructured polymer optical fiber ultrasound sensor for optoacoustic endoscopic imaging in biomedical applications

    DEFF Research Database (Denmark)

    Gallego, Daniel; Sáez-Rodríguez, David; Webb, David

    2014-01-01

    We report a characterization of the acoustic sensitivity of microstructured polymer optical fiber interferometric sensors at ultrasonic frequencies from 100kHz to 10MHz. The use of wide-band ultrasonic fiber optic sensors in biomedical ultrasonic and optoacoustic applications is an open alternative...... interferometric sensors depends strongly of the material which is composed of. In this work we compare experimentally the intrinsic ultrasonic sensitivities of a PMMA mPOF with other three optical fibers: a singlemode silica optical fiber, a single-mode polymer optical fiber and a multimode graded...

  9. Class D audio amplifiers for high voltage capacitive transducers

    DEFF Research Database (Denmark)

    Nielsen, Dennis

    voltage capacitive transducers can be constructed with THD+N below 0.1 % and peak efficiency above 80 %. However the complexity of the amplifier combined with the current high cost of components, makes the technology of DEAP based loudspeaker unfeasible. Suggestions to future work in the pursuit...... of high volume, weight, and cost. High efficient class D amplifiers are now widely available offering power densities, that their linear counterparts can not match. Unlike the technology of audio amplifiers, the loudspeaker is still based on the traditional electrodynamic transducer invented by C.W. Rice....... Due to the similarities between the electrostatic loudspeaker and the DEAP transducer, the state-of-the-art has a special focus on amplifiers for electrostatic loudspeakers. Amplifiers for other type of capacitive transducers like piezoelectric ones are also considered. Finally the current state...

  10. Stress Sensors and Signal Transducers in Cyanobacteria

    Directory of Open Access Journals (Sweden)

    Sergey Kryazhov

    2010-03-01

    Full Text Available In living cells, the perception of environmental stress and the subsequent transduction of stress signals are primary events in the acclimation to changes in the environment. Some molecular sensors and transducers of environmental stress cannot be identified by traditional and conventional methods. Based on genomic information, a systematic approach has been applied to the solution of this problem in cyanobacteria, involving mutagenesis of potential sensors and signal transducers in combination with DNA microarray analyses for the genome-wide expression of genes. Forty-five genes for the histidine kinases (Hiks, 12 genes for serine-threonine protein kinases (Spks, 42 genes for response regulators (Rres, seven genes for RNA polymerase sigma factors, and nearly 70 genes for transcription factors have been successfully inactivated by targeted mutagenesis in the unicellular cyanobacterium Synechocystis sp. PCC 6803. Screening of mutant libraries by genome-wide DNA microarray analysis under various stress and non-stress conditions has allowed identification of proteins that perceive and transduce signals of environmental stress. Here we summarize recent progress in the identification of sensory and regulatory systems, including Hiks, Rres, Spks, sigma factors, transcription factors, and the role of genomic DNA supercoiling in the regulation of the responses of cyanobacterial cells to various types of stress.

  11. Characterization of Dielectric Electroactive Polymer transducers

    DEFF Research Database (Denmark)

    Nielsen, Dennis; Møller, Martin B.; Sarban, Rahimullah;

    2014-01-01

    This paper analysis the small-signal model of the Dielectric Electro Active Polymer (DEAP) transducer. The DEAP transducer have been proposed as an alternative to the electrodynamic transducer in sound reproduction systems. In order to understand how the DEAP transducer works, and provide...

  12. Noninvasive in vivo multispectral optoacoustic imaging of apoptosis in triple negative breast cancer using indocyanine green conjugated phosphatidylserine monoclonal antibody

    Science.gov (United States)

    Kannadorai, Ravi Kumar; Udumala, Sunil Kumar; Sidney, Yu Wing Kwong

    2016-12-01

    Noninvasive and nonradioactive imaging modality to track and image apoptosis during chemotherapy of triple negative breast cancer is much needed for an effective treatment plan. Phosphatidylserine (PS) is a biomarker transiently exposed on the outer surface of the cells during apoptosis. Its externalization occurs within a few hours of an apoptotic stimulus by a chemotherapy drug and leads to presentation of millions of phospholipid molecules per apoptotic cell on the cell surface. This makes PS an abundant and accessible target for apoptosis imaging. In the current work, we show that PS monoclonal antibody tagged with indocyanine green (ICG) can help to track and image apoptosis using multispectral optoacoustic tomography in vivo. When compared to saline control, the doxorubicin treated group showed a significant increase in uptake of ICG-PS monoclonal antibody in triple negative breast tumor xenografted in NCr nude female mice. Day 5 posttreatment had the highest optoacoustic signal in the tumor region, indicating maximum apoptosis and the tumor subsequently shrank. Since multispectral optoacoustic imaging does not involve the use of radioactivity, the longer the circulatory time of the PS antibody can be exploited to monitor apoptosis over a period of time without multiple injections of commonly used imaging probes such as Tc-99m Annexin V or F-18 ML10. The proposed apoptosis imaging technique involving multispectral optoacoustic tomography, monoclonal antibody, and near-infrared absorbing fluorescent marker can be an effective tool for imaging apoptosis and treatment planning.

  13. Noninvasive in vivo multispectral optoacoustic imaging of apoptosis in triple negative breast cancer using indocyanine green conjugated phosphatidylserine monoclonal antibody.

    Science.gov (United States)

    Kannadorai, Ravi Kumar; Udumala, Sunil Kumar; Sidney, Yu Wing Kwong

    2016-12-01

    Noninvasive and nonradioactive imaging modality to track and image apoptosis during chemotherapy of triple negative breast cancer is much needed for an effective treatment plan. Phosphatidylserine (PS) is a biomarker transiently exposed on the outer surface of the cells during apoptosis. Its externalization occurs within a few hours of an apoptotic stimulus by a chemotherapy drug and leads to presentation of millions of phospholipid molecules per apoptotic cell on the cell surface. This makes PS an abundant and accessible target for apoptosis imaging. In the current work, we show that PS monoclonal antibody tagged with indocyanine green (ICG) can help to track and image apoptosis using multispectral optoacoustic tomography triple negative breast tumor xenografted in NCr nude female mice. Day 5 posttreatment had the highest optoacoustic signal in the tumor region, indicating maximum apoptosis and the tumor subsequently shrank. Since multispectral optoacoustic imaging does not involve the use of radioactivity, the longer the circulatory time of the PS antibody can be exploited to monitor apoptosis over a period of time without multiple injections of commonly used imaging probes such as Tc-99m Annexin V or F-18 ML10. The proposed apoptosis imaging technique involving multispectral optoacoustic tomography, monoclonal antibody, and near-infrared absorbing fluorescent marker can be an effective tool for imaging apoptosis and treatment planning.

  14. Signal and response properties indicate an optoacoustic effect underlying the intra-cochlear laser-optical stimulation

    Science.gov (United States)

    Kallweit, Nicole; Baumhoff, Peter; Krueger, Alexander; Tinne, Nadine; Heisterkamp, Alexander; Kral, Andrej; Maier, Hannes; Ripken, Tammo

    2016-02-01

    Optical cochlea stimulation is under investigation as a potential alternative to conventional electric cochlea implants in treatment of sensorineural hearing loss. If direct optical stimulation of spiral ganglion neurons (SGNs) would be feasible, a smaller stimulation volume and, therefore, an improved frequency resolution could be achieved. However, it is unclear whether the mechanism of optical stimulation is based on direct neuronal stimulation or on optoacoustics. Animal studies on hearing vs. deafened guinea pigs already identified the optoacoustic effect as potential mechanism for intra-cochlear optical stimulation. In order to characterize the optoacoustic stimulus more thoroughly the acoustic signal along the beam path of a pulsed laser in water was quantified and compared to the neuronal response properties of hearing guinea pigs stimulated with the same laser parameters. Two pulsed laser systems were used for analyzing the influence of variable pulse duration, pulse energy, pulse peak power and absorption coefficient. Preliminary results of the experiments in water and in vivo suggesta similar dependency of response signals on the applied laser parameters: Both datasets show an onset and offset signal at the beginning and the end of the laser pulse. Further, the resulting signal amplitude depends on the pulse peak power as well as the temporal development of the applied laser pulse. The data indicates the maximum of the first derivative of power as the decisive factor. In conclusion our findings strengthen the hypothesis of optoacoustics as the underlying mechanism for optical stimulation of the cochlea.

  15. Optoacoustic measurement of central venous oxygenation for assessment of circulatory shock: clinical study in cardiac surgery patients

    Science.gov (United States)

    Petrov, Irene Y.; Prough, Donald S.; Kinsky, Michael; Petrov, Yuriy; Petrov, Andrey; Henkel, S. Nan; Seeton, Roger; Salter, Michael G.; Esenaliev, Rinat O.

    2014-03-01

    Circulatory shock is a dangerous medical condition, in which blood flow cannot provide the necessary amount of oxygen to organs and tissues. Currently, its diagnosis and therapy decisions are based on hemodynamic parameters (heart rate, blood pressure, blood gases) and mental status of a patient, which all have low specificity. Measurement of mixed or central venous blood oxygenation via catheters is more reliable, but highly invasive and associated with complications. Our previous studies in healthy volunteers demonstrated that optoacoustic systems provide non-invasive measurement of blood oxygenation in specific vessels, including central veins. Here we report our first results of a clinical study in coronary artery bypass graft (CABG) surgery patients. We used a medical-grade OPO-based optoacoustic system developed in our laboratory to measure in real time blood oxygenation in the internal jugular vein (IJV) of these patients. A clinical ultrasound imaging system (GE Vivid e) was used for IJV localization. Catheters were placed in the IJV as part of routine care and blood samples taken via the catheters were processed with a CO-oximeter. The optoacoustic oxygenation data were compared to the CO-oximeter readings. Good correlation between the noninvasive and invasive measurements was obtained. The results of these studies suggest that the optoacoustic system can provide accurate, noninvasive measurements of central venous oxygenation that can be used for patients with circulatory shock.

  16. Improvement of signal-to-noise ratio of optoacoustic signals from double-walled carbon nanotubes by using an array of dual-wavelength high-power diode lasers

    Science.gov (United States)

    Leggio, Luca; de Varona, Omar E.; Escudero, Pedro; Carpintero del Barrio, Guillermo; Osiński, Marek; Lamela Rivera, Horacio

    2015-07-01

    Optoacoustic (OA) imaging is a rising biomedical technique that has attracted much interest over the last 15 years. This technique permits to visualize the internal soft tissues in depth by using short laser pulses, able to generate ultrasonic signals in a large frequency range. It combines the high contrast of optical imaging with the high resolution of ultrasound systems. The OA signals detected from the whole surface of the body serve to reconstruct in detail the image of the internal tissues, where the absorbed optical energy distribution outlines the regions of interest. In fact, the use of contrast agents could improve the detection of growing anomalies in soft tissues, such as carcinomas. This work proposes the use of double-walled carbon nanotubes (DWCNTs) as a potential nontoxic biodegradable contrast agent applicable in OA to reveal the presence of malignant in-depth tissues in near infrared (NIR) wavelength range (0.75-1.4 μm), where the biological tissues are fairly transparent to optical radiation. A dual-wavelength (870 and 905 nm) OA system is presented, based on arrays of high power diode lasers (HPDLs) that generate ultrasound signals from a DWCNT solution embedded within a biological phantom. The OA signals generated by DWCNTs are compared with those obtained using black ink, considered to be a very good absorber at these wavelengths. The experiments prove that DWCNTs are a potential contrast agent for optoacoustic spectroscopy (OAS).

  17. Ultrasonic Transducer Irradiation Test Results

    Energy Technology Data Exchange (ETDEWEB)

    Daw, Joshua [Idaho National Lab. (INL), Idaho Falls, ID (United States); Palmer, Joe [Idaho National Lab. (INL), Idaho Falls, ID (United States); Ramuhalli, Pradeep [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Keller, Paul [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Montgomery, Robert [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Chien, Hual-Te [Argonne National Lab. (ANL), Argonne, IL (United States); Kohse, Gordon [MIT (Massachusetts Inst. of Technology), Cambridge, MA (United States); Tittmann, Bernhard [Pennsylvania State Univ., University Park, PA (United States); Reinhardt, Brian [Pennsylvania State Univ., University Park, PA (United States); Rempe, Joy [Rempe and Associates, Idaho Falls, ID (United States)

    2015-02-01

    Ultrasonic technologies offer the potential for high-accuracy and -resolution in-pile measurement of a range of parameters, including geometry changes, temperature, crack initiation and growth, gas pressure and composition, and microstructural changes. Many Department of Energy-Office of Nuclear Energy (DOE-NE) programs are exploring the use of ultrasonic technologies to provide enhanced sensors for in-pile instrumentation during irradiation testing. For example, the ability of small diameter ultrasonic thermometers (UTs) to provide a temperature profile in candidate metallic and oxide fuel would provide much needed data for validating new fuel performance models. Other ongoing efforts include an ultrasonic technique to detect morphology changes (such as crack initiation and growth) and acoustic techniques to evaluate fission gas composition and pressure. These efforts are limited by the lack of identified ultrasonic transducer materials capable of long term performance under irradiation test conditions. For this reason, the Pennsylvania State University (PSU) was awarded an ATR NSUF project to evaluate the performance of promising magnetostrictive and piezoelectric transducers in the Massachusetts Institute of Technology Research Reactor (MITR) up to a fast fluence of at least 1021 n/cm2. The goal of this research is to characterize and demonstrate magnetostrictive and piezoelectric transducer operation during irradiation, enabling the development of novel radiation-tolerant ultrasonic sensors for use in Material Testing Reactors (MTRs). As such, this test is an instrumented lead test and real-time transducer performance data is collected along with temperature and neutron and gamma flux data. The current work bridges the gap between proven out-of-pile ultrasonic techniques and in-pile deployment of ultrasonic sensors by acquiring the data necessary to demonstrate the performance of ultrasonic transducers. To date, one piezoelectric

  18. Auto-positioning ultrasonic transducer system

    Science.gov (United States)

    Buchanan, Randy K. (Inventor)

    2010-01-01

    An ultrasonic transducer apparatus and process for determining the optimal transducer position for flow measurement along a conduit outer surface. The apparatus includes a transmitting transducer for transmitting an ultrasonic signal, said transducer affixed to a conduit outer surface; a guide rail attached to a receiving transducer for guiding movement of a receiving transducer along the conduit outer surface, wherein the receiving transducer receives an ultrasonic signal from the transmitting transducer and sends a signal to a data acquisition system; and a motor for moving the receiving transducer along the guide rail, wherein the motor is controlled by a controller. The method includes affixing a transmitting transducer to an outer surface of a conduit; moving a receiving transducer on the conduit outer surface, wherein the receiving transducer is moved along a guide rail by a motor; transmitting an ultrasonic signal from the transmitting transducer that is received by the receiving transducer; communicating the signal received by the receiving transducer to a data acquisition and control system; and repeating the moving, transmitting, and communicating along a length of the conduit.

  19. Comparison of the optoacoustic signal generation efficiency of different nanoparticular contrast agents.

    Science.gov (United States)

    Bost, Wolfgang; Lemor, Robert; Fournelle, Marc

    2012-11-20

    Optoacoustic imaging represents a new modality that allows noninvasive in vivo molecular imaging with optical contrast and acoustical resolution. Whereas structural or functional imaging applications such as imaging of vasculature do not require contrast enhancing agents, nanoprobes with defined biochemical binding behavior are needed for molecular imaging tasks. Since the contrast of this modality is based on the local optical absorption coefficient, all particle or molecule types that show significant absorption cross sections in the spectral range of the laser wavelength used for signal generation are suitable contrast agents. Currently, several particle types such as gold nanospheres, nanoshells, nanorods, or polymer particles are used as optoacoustic contrast agents. These particles have specific advantages with respect to their absorption properties, or in terms of biologically relevant features (biodegradability, binding to molecular markers). In the present study, a comparative analysis of the signal generation efficiency of gold nanorods, polymeric particles, and magnetite particles using a 1064 nm Nd:YAG laser for signal generation is described.

  20. Efficient non-negative constrained model-based inversion in optoacoustic tomography

    Science.gov (United States)

    Ding, Lu; Luís Deán-Ben, X.; Lutzweiler, Christian; Razansky, Daniel; Ntziachristos, Vasilis

    2015-09-01

    The inversion accuracy in optoacoustic tomography depends on a number of parameters, including the number of detectors employed, discrete sampling issues or imperfectness of the forward model. These parameters result in ambiguities on the reconstructed image. A common ambiguity is the appearance of negative values, which have no physical meaning since optical absorption can only be higher or equal than zero. We investigate herein algorithms that impose non-negative constraints in model-based optoacoustic inversion. Several state-of-the-art non-negative constrained algorithms are analyzed. Furthermore, an algorithm based on the conjugate gradient method is introduced in this work. We are particularly interested in investigating whether positive restrictions lead to accurate solutions or drive the appearance of errors and artifacts. It is shown that the computational performance of non-negative constrained inversion is higher for the introduced algorithm than for the other algorithms, while yielding equivalent results. The experimental performance of this inversion procedure is then tested in phantoms and small animals, showing an improvement in image quality and quantitativeness with respect to the unconstrained approach. The study performed validates the use of non-negative constraints for improving image accuracy compared to unconstrained methods, while maintaining computational efficiency.

  1. An analytical model of a longitudinal-torsional ultrasonic transducer

    Science.gov (United States)

    Al-Budairi, Hassan; Lucas, Margaret

    2012-08-01

    The combination of longitudinal and torsional (LT) vibrations at high frequencies finds many applications such as ultrasonic drilling, ultrasonic welding, and ultrasonic motors. The LT mode can be obtained by modifications to the design of a standard bolted Langevin ultrasonic transducer driven by an axially poled piezoceramic stack, by a technique that degenerates the longitudinal mode to an LT motion by a geometrical alteration of the wave path. The transducer design is developed and optimised through numerical modelling which can represent the geometry and mechanical properties of the transducer and its vibration response to an electrical input applied across the piezoceramic stack. However, although these models can allow accurate descriptions of the mechanical behaviour, they do not generally provide adequate insights into the electrical characteristics of the transducer. In this work, an analytical model is developed to present the LT transducer based on the equivalent circuit method. This model can represent both the mechanical and electrical aspects and is used to extract many of the design parameters, such as resonance and anti-resonance frequencies, the impedance spectra and the coupling coefficient of the transducer. The validity of the analytical model is demonstrated by close agreement with experimental results.

  2. Study of the compact fiber optic photoacoustic ultrasonic transducer

    Science.gov (United States)

    Wu, Nan; Tian, Ye; Zou, Xiaotian; Wang, Xingwei

    2012-04-01

    Recently, many studies have been exerted on developing ultrasonic transducers that can feature high frequencies for better resolutions and compact sizes for the limit space nondestructive testing applications. Conventional ultrasonic transducers, which are made by piezoelectric materials, suffer from issues such as low frequencies and bulky sizes due to the difficulty of dicing piezoelectric materials into smaller pieces. On the other hand, generating ultrasonic signals by photoacoustic principle is a promising way to generate a high frequency ultrasonic pulse. Optical fiber is a very compact material that can carry the light energy. By combining the photoacoustic principle and the optical fiber together, a novel ultrasonic transducer that features a high frequency and a compact size could be achieved. In this paper, an ultrasonic transducer using gold nanoparticles as the photoacoustic generation material is described. Gold nanoparticles are deposited on the end surface of an optical fiber acting as the ultrasonic generator. A cavity and a diaphragm are fabricated in the center of the fiber using as the ultrasonic receiver. A phase array technique is applied to the transducer to steer the direction of the acoustic beam. Simulation results demonstrated that the photoacoustic ultrasonic transducer is feasible.

  3. Ultrasound transducer assembly and method for manufacturing an ultrasound transducer assembly

    NARCIS (Netherlands)

    Dekker, R.; Henneken, V.A.; Louwerse, M.C.; Raganato, M.F.

    2015-01-01

    The present invention relates to an ultrasound transducer assembly (10), in particular for intravascular ultrasound systems. The ultrasound transducer assembly comprises at least one silicon substrate element (30) including an ultrasound transducer element (14) for emitting and receiving ultrasound

  4. Ultrasound transducer assembly and method for manufacturing an ultrasound transducer assembly

    NARCIS (Netherlands)

    Dekker, R.; Henneken, V.A.; Louwerse, M.C.; Raganato, M.F.

    2015-01-01

    The present invention relates to an ultrasound transducer assembly (10), in particular for intravascular ultrasound systems. The ultrasound transducer assembly comprises at least one silicon substrate element (30) including an ultrasound transducer element (14) for emitting and receiving ultrasound

  5. Calculations for Piezoelectric Ultrasonic Transducers

    DEFF Research Database (Denmark)

    Jensen, Henrik

    1986-01-01

    Analysis of piezoelectric ultrasonic transducers implies a solution of a boundary value problem, for a boay which consists of different materials, including a piezoelectric part. The problem is dynamic at frequencies, where a typical wavelength is somewhat less than the size of the body. Radiation...... and in particular the finite element method are considered. The finite element method is utilized for analysis of axisymmetric transducers. An explicit, fully piezoelectric, triangular ring element, with linear variations in displacememnt and electric potential is given. The influence of a fluid half-space is also...

  6. Non-bonded ultrasonic transducer

    Science.gov (United States)

    Eoff, J.M.

    1984-07-06

    A mechanically assembled non-bonded ultrasonic transducer includes a substrate, a piezoelectric film, a wetting agent, a thin metal electrode, and a lens held in intimate contact by a mechanical clamp. No epoxy or glue is used in the assembly of this device.

  7. Acoustic transducer for acoustic microscopy

    Science.gov (United States)

    Khuri-Yakub, Butrus T.; Chou, Ching H.

    1990-01-01

    A shear acoustic transducer-lens system in which a shear polarized piezoelectric material excites shear polarized waves at one end of a buffer rod having a lens at the other end which excites longitudinal waves in a coupling medium by mode conversion at selected locations on the lens.

  8. Vacuum mounting for piezoelectric transducers

    Science.gov (United States)

    Tiede, D. A.

    1977-01-01

    Special housing couples piezoelectric transducers to nonporous surfaces for ultrasonic or acoustic-emission testing. Device, while providing sound isolation on flat or nonflat surfaces, can be attached and detached quickly. Vacuum sealing mechanism eliminates need for permanent or semipermanent bonds, viscous coupling liquids, weights, magnets, tape, or springs ordinarily used.

  9. Enhanced C-band Coaxial Orthomode Transducer

    Directory of Open Access Journals (Sweden)

    S. I. Piltyay

    2014-06-01

    Full Text Available Introduction. In this paper a novel configuration of wideband coherent coaxial OMT is presented. General Design of an Orthomode Transducer. The OMT consists of elements of 3 main types: a turnstile junction between coaxial quad-ridged waveguide and 4 coaxial transmission lines; 4 right-angle coaxial junctions for each polarization; 2 antiphase power combiners/dividers. A Turnstile Junction Optimization. The optimization of a turnstile junction has been performed. Its minimized reflection coefficient is less than −28 dB in the operation frequency band 3.4–5.4 GHz. An Optimized Right-Angle Coaxial Junction. A right-angle coaxial junction has been optimized to provide reflection coefficient, which is less than −42 dB in the operation frequency band 3.4–5.4 GHz. An Antiphase Power Combiner/Divider. The optimization of an antiphase power com-biner/divider has been performed. Its minimized reflection coefficient is less than −38 dB. Conclusions. A wideband coaxial orthomode transducer has been developed for the operation frequency band 3.4–5.4 GHz. In this frequency band the reflection coefficient is less than −27 dB.

  10. Irradiation Testing of Ultrasonic Transducers

    Energy Technology Data Exchange (ETDEWEB)

    Daw, Joshua; Tittmann, Bernhard; Reinhardt, Brian; Kohse, Gordon E.; Ramuhalli, Pradeep; Montgomery, Robert O.; Chien, Hual-Te; Villard, Jean-Francois; Palmer, Joe; Rempe, Joy

    2014-07-30

    Ultrasonic technologies offer the potential for high accuracy and resolution in-pile measurement of a range of parameters, including geometry changes, temperature, crack initiation and growth, gas pressure and composition, and microstructural changes. Many Department of Energy-Office of Nuclear Energy (DOE-NE) programs are exploring the use of ultrasonic technologies to provide enhanced sensors for in-pile instrumentation during irradiation testing. For example, the ability of single, small diameter ultrasonic thermometers (UTs) to provide a temperature profile in candidate metallic and oxide fuel would provide much needed data for validating new fuel performance models. Other efforts include an ultrasonic technique to detect morphology changes (such as crack initiation and growth) and acoustic techniques to evaluate fission gas composition and pressure. These efforts are limited by the lack of existing knowledge of ultrasonic transducer material survivability under irradiation conditions. For this reason, the Pennsylvania State University (PSU) was awarded an Advanced Test Reactor National Scientific User Facility (ATR NSUF) project to evaluate promising magnetostrictive and piezoelectric transducer performance in the Massachusetts Institute of Technology Research Reactor (MITR) up to a fast fluence of at least 1021 n/cm2 (E> 0.1 MeV). The goal of this research is to characterize magnetostrictive and piezoelectric transducer survivability during irradiation, enabling the development of novel radiation tolerant ultrasonic sensors for use in Material and Test Reactors (MTRs). As such, this test will be an instrumented lead test and real-time transducer performance data will be collected along with temperature and neutron and gamma flux data. The current work bridges the gap between proven out-of-pile ultrasonic techniques and in-pile deployment of ultrasonic sensors by acquiring the data necessary to demonstrate the performance of ultrasonic transducers.

  11. Wideband Single Crystal Transducer for Bone Characterization

    Science.gov (United States)

    Sahul, Raffi

    2015-01-01

    Phase II objectives: Optimize the Phase I transducer for sensitivity; Test different transmit signals for optimum performance; Demonstrate compatibility with electronics; Confirm additional transducer capabilities over conventional systems by calibrating with other methods.

  12. Transducers and Arrays for Underwater Sound

    CERN Document Server

    Sherman, Charles H

    2007-01-01

    This book is concerned with the theory, development and design of electroacoustic transducers for underwater applications, and is more comprehensive than any existing book in this field. It includes the basics of the six major types of electroacoustic transducers, with emphasis on the piezoelectric ceramic transducers that are currently most widely used. It presents the basic acoustics, as well as specific acoustic data, needed in transducer design and includes analysis of nonlinear effects in transducers. A large number of specific transducer designs, including both projectors and hydrophones, are described in detail as well as methods of modeling, evaluation and measurement. Analysis of transducer arrays, including the effects of mutual radiation impedance, as well as numerical models for transducers and arrays are also covered. The book contains an extensive Appendix of useful current information, including data on the latest transduction materials, and numerous diagrams that will facilitate its use by stu...

  13. A Direct Driver for Electrostatic Transducers

    DEFF Research Database (Denmark)

    Nielsen, Dennis; Knott, Arnold; Andersen, Michael A. E.

    2014-01-01

    Electrostatic transducers represent a very interesting alternative to the traditional inefficient electrodynamic transducers. In order to establish the full potential of these transducers, power amplifiers which fulfill the strict requirements imposed by such loads (high impedance, frequency...... depended, nonlinear and high bias voltage for linearization) must be developed. This paper analyzes a power stage suitable for driving an electrostatic transducer under biasing. Measurement results of a ±400 V prototype amplifier are shown. THD below 1% is reported....

  14. Opto-acoustic image fusion technology for diagnostic breast imaging in a feasibility study

    Science.gov (United States)

    Zalev, Jason; Clingman, Bryan; Herzog, Don; Miller, Tom; Ulissey, Michael; Stavros, A. T.; Oraevsky, Alexander; Lavin, Philip; Kist, Kenneth; Dornbluth, N. C.; Otto, Pamela

    2015-03-01

    Functional opto-acoustic (OA) imaging was fused with gray-scale ultrasound acquired using a specialized duplex handheld probe. Feasibility Study findings indicated the potential to more accurately characterize breast masses for cancer than conventional diagnostic ultrasound (CDU). The Feasibility Study included OA imagery of 74 breast masses that were collected using the investigational Imagio® breast imaging system. Superior specificity and equal sensitivity to CDU was demonstrated, suggesting that OA fusion imaging may potentially obviate the need for negative biopsies without missing cancers in a certain percentage of breast masses. Preliminary results from a 100 subject Pilot Study are also discussed. A larger Pivotal Study (n=2,097 subjects) is underway to confirm the Feasibility Study and Pilot Study findings.

  15. Multiscale edge detection and parametric shape modeling for boundary delineation in optoacoustic images

    CERN Document Server

    Mandal, Subhamoy; Nagaraj, Yeshaswini; Ben, Xose Luis Dean; Razansky, Daniel

    2015-01-01

    In this article, we present a novel scheme for segmenting the image boundary (with the background) in optoacoustic small animal in vivo imaging systems. The method utilizes a multiscale edge detection algorithm to generate a binary edge map. A scale dependent morphological operation is employed to clean spurious edges. Thereafter, an ellipse is fitted to the edge map through constrained parametric transformations and iterative goodness of fit calculations. The method delimits the tissue edges through the curve fitting model, which has shown high levels of accuracy. Thus, this method enables segmentation of optoacoutic images with minimal human intervention, by eliminating need of scale selection for multiscale processing and seed point determination for contour mapping.

  16. Fabry-Perot micro-structured polymer optical fibre sensors for opto-acoustic endoscopy

    DEFF Research Database (Denmark)

    Broadway, Christian; Gallego, Daniel; Woyessa, Getinet

    2015-01-01

    Opto-Acoustic Endoscopy (OAE) requires sensors with a high sensitivity and small physical dimensions in order to facilitate integration into an endoscope of less than 1mm in diameter. We present fibre Bragg grating (FBG) and Fabry- Perot intrinsic fibre sensors for ultrasound detection. We present...... a structure profile characterisation setup to analyse tune the fibre sensors in preparation for ultrasonic detection. We evaluate the suitability of the different structures and grating parameters for ultrasonic sensing. By analysing the prepared gratings, we enable the optimisation of the profile...... and a simplification of the detection regime for an optimal interferometric OAE configuration. © (2015) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only....

  17. Eigenspectra optoacoustic tomography achieves quantitative blood oxygenation imaging deep in tissues

    CERN Document Server

    Tzoumas, Stratis; Olefir, Ivan; Stangl, Stefan; Symvoulidis, Panagiotis; Glasl, Sarah; Bayer, Christine; Multhoff, Gabriele; Ntziachristos, Vasilis

    2015-01-01

    Light propagating in tissue attains a spectrum that varies with location due to wavelength-dependent fluence attenuation by tissue optical properties, an effect that causes spectral corruption. Predictions of the spectral variations of light fluence in tissue are challenging since the spatial distribution of optical properties in tissue cannot be resolved in high resolution or with high accuracy by current methods. Spectral corruption has fundamentally limited the quantification accuracy of optical and optoacoustic methods and impeded the long sought-after goal of imaging blood oxygen saturation (sO2) deep in tissues; a critical but still unattainable target for the assessment of oxygenation in physiological processes and disease. We discover a new principle underlying light fluence in tissues, which describes the wavelength dependence of light fluence as an affine function of a few reference base spectra, independently of the specific distribution of tissue optical properties. This finding enables the introd...

  18. Multiscale edge detection and parametric shape modeling for boundary delineation in optoacoustic images.

    Science.gov (United States)

    Mandal, S; Viswanath, P S; Yeshaswini, N; Dean-Ben, X L; Razansky, D

    2015-08-01

    In this article, we present a novel scheme for segmenting the image boundary (with the background) in optoacoustic small animal in vivo imaging systems. The method utilizes a multiscale edge detection algorithm to generate a binary edge map. A scale dependent morphological operation is employed to clean spurious edges. Thereafter, an ellipse is fitted to the edge map through constrained parametric transformations and iterative goodness of fit calculations. The method delimits the tissue edges through the curve fitting model, which has shown high levels of accuracy. Thus, this method enables segmentation of optoacoutic images with minimal human intervention, by eliminating need of scale selection for multiscale processing and seed point determination for contour mapping.

  19. Impact of non-stationary optical illumination on image reconstruction in optoacoustic tomography

    CERN Document Server

    Lou, Yang; Oraevsky, Alexander A; Anastasio, Mark A

    2016-01-01

    Optoacoustic tomography (OAT), also known as photoacoustic tomography, is a rapidly emerging hybrid imaging technique that possesses great potential for a wide range of biomedical imaging applications. In OAT, a laser is employed to illuminate the tissue of interest and acoustic signals are produced via the photoacoustic effect. From these data, an estimate of the distribution of the absorbed optical energy density within the tissue is reconstructed, referred to as the object function. This quantity is defined, in part, by the distribution of light fluence within the tissue that is established by the laser source. When performing three-dimensional imaging of large objects, such as a female human breast, it can be difficult to achieve a relatively uniform coverage of light fluence within the volume of interest when the position of the laser source is fixed. To circumvent this, researchers have proposed illumination schemes in which the relative position of the laser source and ultrasound probe is fixed, and bo...

  20. Blob-Based Discrete Imaging Models for Three-Dimensional Optoacoustic Tomography

    CERN Document Server

    Wang, Kun; Su, Richard; Oraevsky, Alexander; Anastasio, Mark A

    2013-01-01

    Optoacoustic tomography (OAT), also known as photoacoustic tomography, is an emerging computed biomedical imaging modality that exploits optical contrast and ultrasonic detection principles. Iterative image reconstruction algorithms that are based on discrete imaging models are actively being developed for OAT due to their ability to improve image quality by incorporating accurate models of the imaging physics, instrument response, and measurement noise.In this work, we investigate the use of discrete imaging models based on Kaiser-Bessel window functions, or `blobs', for iterative image reconstruction in OAT.A closed-form expression for the pressure produced by a blob function is calculated, which facilitates accurate computation of the system matrix. Computer-simulation and experimental studies are employed to demonstrate the potential advantages of blob-based iterative image reconstruction in OAT.

  1. Acousto-Optic Modulation and Optoacoustic Gating in Piezo-Optomechanical Circuits

    Science.gov (United States)

    Balram, Krishna C.; Davanço, Marcelo I.; Ilic, B. Robert; Kyhm, Ji-Hoon; Song, Jin Dong; Srinivasan, Kartik

    2017-02-01

    Acoustic-wave devices provide a promising chip-scale platform for efficiently coupling radio frequency (rf) and optical fields. Here, we use an integrated piezo-optomechanical circuit platform that exploits both the piezoelectric and photoelastic coupling mechanisms to link 2.4-GHz rf waves to 194-THz (1550 nm) optical waves, through coupling to propagating and localized 2.4-GHz acoustic waves. We demonstrate acousto-optic modulation, resonant in both the optical and mechanical domains, in which waveforms encoded on the rf carrier are mapped to the optical field. We also show optoacoustic gating, in which the application of modulated optical pulses interferometrically gates the transmission of propagating acoustic pulses. The time-domain characteristics of this system under both pulsed rf and pulsed optical excitation are considered in the context of the different physical pathways involved in driving the acoustic waves, and modeled through the coupled mode equations of cavity optomechanics.

  2. Method and apparatus for background signal reduction in opto-acoustic absorption measurement

    Science.gov (United States)

    Rosengren, L. G. (Inventor)

    1976-01-01

    The sensitivity of an opto-acoustic absorption detector is increased to make it possible to measure trace amounts of constituent gases. A second beam radiation path is created through the sample cell identical to a first path except as to length, alternating the beam through the two paths and minimizing the detected pressure difference for the two paths while the beam wavelength is tuned away from the absorption lines of the sample. Then with the beam wavelength tuned to the absorption line of any constituent of interest, the pressure difference is a measure of trace amounts of the constituent. The same improved detector may also be used for measuring the absorption coefficient of known concentrations of absorbing gases.

  3. Acousto-optic and opto-acoustic modulation in piezo-optomechanical circuits

    CERN Document Server

    Balram, Krishna C; Ilic, B Robert; Kyhm, Ji-Hoon; Song, Jin Dong; Srinivasan, Kartik

    2016-01-01

    Acoustic wave devices provide a promising chip-scale platform for efficiently coupling radio frequency (RF) and optical fields. Here, we use an integrated piezo-optomechanical circuit platform that exploits both the piezoelectric and photoelastic coupling mechanisms to link 2.4 GHz RF waves to 194 THz (1550 nm) optical waves, through coupling to propagating and localized 2.4 GHz acoustic waves. We demonstrate acousto-optic modulation, resonant in both the optical and mechanical domains, in which waveforms encoded on the RF carrier are mapped to the optical field. We also show opto-acoustic modulation, in which the application of optical pulses gates the transmission of propagating acoustic waves. The time-domain characteristics of this system under both pulsed RF and pulsed optical excitation are considered in the context of the different physical pathways involved in driving the acoustic waves, and modeled through the coupled mode equations of cavity optomechanics.

  4. Accelerating Image Reconstruction in Three-Dimensional Optoacoustic Tomography on Graphics Processing Units

    CERN Document Server

    Wang, Kun; Kao, Yu-Jiun; Chou, Cheng-Ying; Oraevsky, Alexander A; Anastasio, Mark A; 10.1118/1.4774361

    2013-01-01

    Purpose: Optoacoustic tomography (OAT) is inherently a three-dimensional (3D) inverse problem. However, most studies of OAT image reconstruction still employ two-dimensional (2D) imaging models. One important reason is because 3D image reconstruction is computationally burdensome. The aim of this work is to accelerate existing image reconstruction algorithms for 3D OAT by use of parallel programming techniques. Methods: Parallelization strategies are proposed to accelerate a filtered backprojection (FBP) algorithm and two different pairs of projection/backprojection operations that correspond to two different numerical imaging models. The algorithms are designed to fully exploit the parallel computing power of graphic processing units (GPUs). In order to evaluate the parallelization strategies for the projection/backprojection pairs, an iterative image reconstruction algorithm is implemented. Computer-simulation and experimental studies are conducted to investigate the computational efficiency and numerical a...

  5. Hybrid multispectral optoacoustic and ultrasound tomography for morphological and physiological brain imaging

    Science.gov (United States)

    Olefir, Ivan; Merčep, Elena; Burton, Neal C.; Ovsepian, Saak V.; Ntziachristos, Vasilis

    2016-08-01

    Expanding usage of small animal models in biomedical research necessitates development of technologies for structural, functional, or molecular imaging that can be readily integrated in the biological laboratory. Herein, we consider dual multispectral optoacoustic (OA) and ultrasound tomography based on curved ultrasound detector arrays and describe the performance achieved for hybrid morphological and physiological brain imaging of mice in vivo. We showcase coregistered hemodynamic parameters resolved by OA tomography under baseline conditions and during alterations of blood oxygen saturation. As an internal reference, we provide imaging of abdominal organs. We illustrate the performance advantages of hybrid curved detector ultrasound and OA tomography and discuss immediate and long-term implications of our findings in the context of animal and human studies.

  6. Transducer for harmonic intravascular ultrasound imaging

    NARCIS (Netherlands)

    Vos, Hendrik J.; Frijlink, Martijn E.; Droog, E.J.; Goertz, David E.; Blacquiere, Gerrit; Gisolf, Anton; de Jong, N.; van der Steen, Antonius F.W.

    2005-01-01

    A recent study has shown the feasibility of tissue harmonic imaging (THI) using an intravascular ultrasound (IVUS) transducer. This correspondence describes the design, fabrication, and characterization of a THI-optimized piezoelectric transducer with oval aperture of 0.75 mm by 1 mm. The transducer

  7. 21 CFR 882.1950 - Tremor transducer.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Tremor transducer. 882.1950 Section 882.1950 Food... DEVICES NEUROLOGICAL DEVICES Neurological Diagnostic Devices § 882.1950 Tremor transducer. (a) Identification. A tremor transducer is a device used to measure the degree of tremor caused by certain diseases...

  8. Noninvasive optoacoustic temperature determination at the fundus of the eye during laser irradiation.

    Science.gov (United States)

    Schule, Georg; Huttmann, Gereon; Framme, Carsten; Roider, Johann; Brinkmann, Ralf

    2004-01-01

    In all fundus laser treatments of the eye, the temperature increase is not exactly known. In order to optimize treatments, an online temperature determination is preferable. We investigated a noninvasive optoacoustic method to monitor the fundus temperature during pulsed laser irradiation. When laser pulses are applied to the fundus, thermoelastic pressure waves are emitted, due to thermal expansion of the heated tissue. Using a constant pulse energy, the amplitude of the pressure wave increases linearly with an increase in the base temperature of between 30 and 80 degrees C. This method was evaluated in vitro on porcine retinal pigment epithelium (RPE) cell samples and clinically during selective RPE treatment with repetitive microsecond laser pulses. During the irradiation of porcine RPE with a neodymium-doped yttrium (Nd:YLF) laser (527 nm, 1.7 micros, 500 Hz repetition rate, 160 mJ/cm(2)) an increase in the base temperature of 30+/-4 degrees C after 100 pulses was found. During patient treatments, a temperature increase of 60+/-11 degrees C after 100 pulses with a 500-Hz repetition rate and 7+/-1 degrees C after 30 pulses with 100 Hz at 520 mJ/cm(2) was found. All measured data were in good agreement with heat diffusion calculations. Optoacoustic methods can be used to noninvasively determine retinal temperatures during pulsed laser treatment of the eye. This technique can also be adapted to continuous-wave photocoagulation, photodynamic therapy and transpupillary thermotherapy, or other fields of laser-heated tissue.

  9. Digital electrostatic acoustic transducer array

    KAUST Repository

    Carreno, Armando Arpys Arevalo

    2016-12-19

    In this paper we present the fabrication and characterization of an array of electrostatic acoustic transducers. The array is micromachined on a silicon wafer using standard micro-machining techniques. Each array contains 2n electrostatic transducer membranes, where “n” is the bit number. Every element of the array has a hexagonal membrane shape structure, which is separated from the substrate by 3µm air gap. The membrane is made out 5µm thick polyimide layer that has a bottom gold electrode on the substrate and a gold top electrode on top of the membrane (250nm). The wafer layout design was diced in nine chips with different array configurations, with variation of the membrane dimensions. The device was tested with 90 V giving and sound output level as high as 35dB, while actuating all the elements at the same time.

  10. Self-Calibrating Pressure Transducer

    Science.gov (United States)

    Lueck, Dale E. (Inventor)

    2006-01-01

    A self-calibrating pressure transducer is disclosed. The device uses an embedded zirconia membrane which pumps a determined quantity of oxygen into the device. The associated pressure can be determined, and thus, the transducer pressure readings can be calibrated. The zirconia membrane obtains oxygen .from the surrounding environment when possible. Otherwise, an oxygen reservoir or other source is utilized. In another embodiment, a reversible fuel cell assembly is used to pump oxygen and hydrogen into the system. Since a known amount of gas is pumped across the cell, the pressure produced can be determined, and thus, the device can be calibrated. An isolation valve system is used to allow the device to be calibrated in situ. Calibration is optionally automated so that calibration can be continuously monitored. The device is preferably a fully integrated MEMS device. Since the device can be calibrated without removing it from the process, reductions in costs and down time are realized.

  11. Advanced Geothermal Optical Transducer (AGOT)

    Energy Technology Data Exchange (ETDEWEB)

    None

    2004-09-01

    Today's geothermal pressure-temperature measuring tools are short endurance, high value instruments, used sparingly because their loss is a major expense. In this project LEL offered to build and test a rugged, affordable, downhole sensor capable ofretuming an uninterrupted data stream at pressures and of 10,000 psi and temperatures up to 250 C, thus permitting continuous deep-well logging. It was proposed to meet the need by specializing LEL's patented 'Twin Column Transducer' technology to satisfy the demands of geothermal pressure/temperature measurements. TCT transducers have very few parts, none of which are moving parts, and all of which can be fabricated from high-temperature super alloys or from ceramics; the result is an extremely rugged device, essentially impervious to chemical attack and readily modified to operate at high pressure and temperature. To measure pressure and temperature they capitalize on the relative expansion of optical elements subjected to thermal or mechanical stresses; if one element is maintained at a reference pressure while the other is opened to ambient, the differential displacement then serves as a measure of pressure. A transducer responding to temperature rather than pressure is neatly created by 'inverting' the pressure-measuring design so that both deflecting structures see identical temperatures and temperature gradients, but whose thermal expansion coefficients are deliberately mismatched to give differential expansion. The starting point for development of a PT Tool was the company's model DPT feedback-stabilized 5,000 psi sensor (U.S. Patent 5,311,014, 'Optical Transducer for Measuring Downhole Pressure', claiming a pressure transducer capable of measuring static, dynamic, and true bi-directional differential pressure at high temperatures), shown in the upper portion of Figure 1. The DPT occupies a 1 x 2 x 4-inch volume, weighs 14 ounces, and is accurate to 1 percent of full

  12. A cylindrical standing wave ultrasonic motor using bending vibration transducer.

    Science.gov (United States)

    Liu, Yingxiang; Chen, Weishan; Liu, Junkao; Shi, Shengjun

    2011-07-01

    A cylindrical standing wave ultrasonic motor using bending vibration transducer was proposed in this paper. The proposed stator contains a cylinder and a bending vibration transducer. The two combining sites between the cylinder and the transducer locate at the adjacent wave loops of bending vibration of the transducer and have a distance that equal to the half wave length of bending standing wave excited in the cylinder. Thus, the bending mode of the cylinder can be excited by the bending vibration of the transducer. Two circular cone type rotors are pressed in contact to the end rims of the teeth, and the preload between the rotors and stator is accomplished by a spring and nut system. The working principle of the proposed motor was analyzed. The motion trajectories of teeth were deduced. The stator was designed and analyzed with FEM. A prototype motor was fabricated and measured. Typical output of the prototype is no-load speed of 165rpm and maximum torque of 0.45Nm at an exciting voltage of 200V(rms).

  13. Elongation Transducer For Tensile Tests

    Science.gov (United States)

    Roberts, Paul W.; Stokes, Thomas R.

    1994-01-01

    Extensometer transducer measures elongation of tensile-test specimen with negligible distortion of test results. Used in stress-versus-strain tests of small specimens of composite materials. Clamping stress distributed more evenly. Specimen clamped gently between jaw and facing surface of housing. Friction force of load points on conical tips onto specimen depends on compression of spring, adjusted by turning cover on housing. Limp, light nylon-insulated electrical leads impose minimal extraneous loads on measuring elements.

  14. Covert Channel Synthesis for Transducers

    OpenAIRE

    Benattar, Gilles; Bérard, Béatrice; Lime, Didier; Mullins, John; Roux, Olivier Henri; Sassolas, Mathieu

    2010-01-01

    Research report; Covert channels are a security threat for information systems, since they permit illegal flows, and sometimes leaks, of classified data. Although numerous descriptions have been given at a concrete level, relatively little work has been carried out at a more abstract level, outside probabilistic models. In this paper, we propose a definition of covert channels based on encoding and decoding binary messages with transducers, in a finite transition system. We first compare this...

  15. Four dimensional hybrid ultrasound and optoacoustic imaging via passive element optical excitation in a hand-held probe

    Energy Technology Data Exchange (ETDEWEB)

    Fehm, Thomas Felix; Razansky, Daniel, E-mail: dr@tum.de [Institute for Biological and Medical Imaging (IBMI), Helmholtz Zentrum München, Neuherberg (Germany); Faculty of Medicine, Technische Universität München, Munich (Germany); Deán-Ben, Xosé Luís [Institute for Biological and Medical Imaging (IBMI), Helmholtz Zentrum München, Neuherberg (Germany)

    2014-10-27

    Ultrasonography and optoacoustic imaging share powerful advantages related to the natural aptitude for real-time image rendering with high resolution, the hand-held operation, and lack of ionizing radiation. The two methods also possess very different yet highly complementary advantages of the mechanical and optical contrast in living tissues. Nonetheless, efficient integration of these modalities remains challenging owing to the fundamental differences in the underlying physical contrast, optimal signal acquisition, and image reconstruction approaches. We report on a method for hybrid acquisition and reconstruction of three-dimensional pulse-echo ultrasound and optoacoustic images in real time based on passive ultrasound generation with an optical absorber, thus avoiding the hardware complexity of active ultrasound generation. In this way, complete hybrid datasets are generated with a single laser interrogation pulse, resulting in simultaneous rendering of ultrasound and optoacoustic images at an unprecedented rate of 10 volumetric frames per second. Performance is subsequently showcased in phantom experiments and in-vivo measurements from a healthy human volunteer, confirming general clinical applicability of the method.

  16. Enhancing endosomal escape of transduced proteins by photochemical internalisation.

    Directory of Open Access Journals (Sweden)

    Kevin Mellert

    Full Text Available Induced internalisation of functional proteins into cultured cells has become an important aspect in a rising number of in vitro and in vivo assays. The endo-lysosomal entrapment of the transduced proteins remains the major problem in all transduction protocols. In this study we compared the efficiency, cytotoxicity and protein targeting of different commercially available transduction reagents by transducing a well-studied fluorescently labelled protein (Atto488-bovine serum albumin into cultured human sarcoma cells. The amount of internalised protein and toxicity differed between the different reagents, but the percentage of transduced cells was consistently high. Furthermore, in all protocols the signals of the transduced Atto488-BSA were predominantly punctual consistent with an endosomal localisation. To overcome the endosomal entrapment, the transduction protocols were combined with a photochemical internalisation (PCI treatment. Using this combination revealed that an endosomal disruption is highly effective in cell penetrating peptide (CPP mediated transduction, whereas lipid-mediated transductions lead to a lower signal spreading throughout the cytosol. No change in the signal distribution could be achieved in treatments using non-lipid polymers as a transduction reagent. Therefore, the combination of protein transduction protocols based on CPPs with the endosomolytic treatment PCI can facilitate protein transduction experiments in vitro.

  17. Micromachined Ultrasonic Transducers for 3-D Imaging

    DEFF Research Database (Denmark)

    Christiansen, Thomas Lehrmann

    such transducer arrays, capacitive micromachined ultrasonic transducer (CMUT) technology is chosen for this project. Properties such as high bandwidth and high design flexibility makes this an attractive transducer technology, which is under continuous development in the research community. A theoretical...... of state-of-the-art 3-D ultrasound systems. The focus is on row-column addressed transducer arrays. This previously sparsely investigated addressing scheme offers a highly reduced number of transducer elements, resulting in reduced transducer manufacturing costs and data processing. To produce......Real-time ultrasound imaging is a widely used technique in medical diagnostics. Recently, ultrasound systems offering real-time imaging in 3-D has emerged. However, the high complexity of the transducer probes and the considerable increase in data to be processed compared to conventional 2-D...

  18. Focused ultrasound transducer for thermal treatment.

    Science.gov (United States)

    Umemura, Shin-ichiro

    2015-03-01

    Air-backed transducers have been employed for thermal ultrasonic treatment including both ablation and hyperthermia because the power efficiency rather than the bandwidth is a main concern, unlike a typical imaging transducer working in a pulse mode. The characteristic of an air-backed piezoelectric transducer with a matching layer is analysed, and the role and choice of the matching layer is discussed. An element size of a focused array transducer, appropriate for such thermal treatment, is then estimated, and the characteristic of a piezoceramic transducer element of such a size was numerically analysed using a finite element code. The characteristic of a piezocomposite transducer element is also numerically analysed and its suitability to such a therapeutic array transducer is discussed.

  19. Numerical comparison of patch and sandwich piezoelectric transducers for transmitting ultrasonic waves

    Science.gov (United States)

    Loveday, Philip W.

    2006-03-01

    Guided wave ultrasonic inspection is becoming an important method of non-destructive testing for long, slender structures such as pipes and rails. Often it is desirable to use transducers that can strongly excite a specific mode of wave propagation in the waveguide. Piezoelectric patch transducers are frequently employed, by researchers, for exciting waves in beam like structures. Sonar systems frequently make use of resonant transducers, such as sandwich transducers, for acoustic wave generation and this principle has been used to excite waves in a rail. This paper compares the two transduction approaches, for launching bending waves in rectangular waveguides, with numerical modeling. The numerical modeling combined a waveguide finite element model, of the waveguide, with conventional three-dimensional piezoelectric finite element models of the transducers. The waveguide finite elements were formulated using a complex exponential to describe the wave propagation along the structure and conventional finite element interpolation over the area of the element. Consequently, only a two-dimensional finite element mesh covering the cross-section of the waveguide is required. The harmonic forced response of the waveguide was used to compute a complex dynamic stiffness matrix which represented the waveguide in the transducer model. The effects of geometrical parameters of patch and sandwich transducers were considered before the comparison was made. It appears that piezoelectric patch transducers offer advantages at low frequencies while sandwich transducers are superior at high frequencies, where resonance can be exploited, at the cost of more complex design.

  20. Particle image velocimetry on simulated 3D ultrafast ultrasound from pediatric matrix TEE transducers

    Science.gov (United States)

    Voorneveld, J. D.; Bera, D.; van der Steen, A. F. W.; de Jong, N.; Bosch, J. G.

    2017-03-01

    Ultrafast 3D transesophageal echocardiographic (TEE) imaging, combined with 3D echo particle image velocimetry (ePIV), would be ideal for tracking the complex blood flow patterns in the heart. We are developing a miniature pediatric matrix TEE transducer that employs micro-beamforming (μBF) and allows high framerate in 3D. In this paper, we assess the feasibility of 3D ePIV with a high frame rate, small aperture transducer and the influence of the micro-beamforming technique. We compare the results of 3D ePIV on simulated images using the μBF transducer and an idealized, fully sampled (FS) matrix transducer. For the two transducers, we have simulated high-framerate imaging of an 8.4mm diameter artery having a known 4D velocity field. The simulations were performed in FieldII. 1000 3D volumes, at a rate of 1000 volumes/sec, were created using a single diverging transmission per volume. The error in the 3D velocity estimation was measured by comparing the ePIV results of both transducers to the ground truth. The results on the simulated volumes show that ePIV can estimate the 4D velocity field of the arterial phantom using these small-aperture transducers suitable for pediatric 3D TEE. The μBF transducer (RMSE 44.0%) achieved comparable ePIV accuracy to that of the FS transducer (RMSE 42.6%).

  1. Transducers

    Digital Repository Service at National Institute of Oceanography (India)

    Chakraborty, B.

    stream_size 27 stream_content_type text/plain stream_name Encycl_Microcomputers_18_335.pdf.txt stream_source_info Encycl_Microcomputers_18_335.pdf.txt Content-Encoding ISO-8859-1 Content-Type text/plain; charset=ISO-8859-1 ...

  2. LAVA Pressure Transducer Trade Study

    Science.gov (United States)

    Oltman, Samuel B.

    2016-01-01

    The Regolith and Environment Science and Oxygen and Lunar Volatile Extraction (RESOLVE) payload will transport the (LAVA) subsystem to hydrogen-rich locations on the moon supporting NASA's in-situ resource utilization (ISRU) programs. There, the LAVA subsystem will analyze volatiles that evolve from heated regolith samples in order to quantify how much water is present. To do this, the system needs resilient pressure transducers (PTs) to calculate the moles in the gas samples. The PT trade study includes a comparison of newly-procured models to a baseline unit with prior flight history in order to determine the PT model with the best survivability in flight-forward conditions.

  3. Analysis of the absorption spectra of gas emission of patients with lung cancer and chronic obstructive pulmonary disease by laser optoacoustic spectroscopy

    Science.gov (United States)

    Bukreeva, Ekaterina B.; Bulanova, Anna A.; Kistenev, Yurii V.; Kuzmin, Dmitry A.; Tuzikov, Sergei A.; Yumov, Evgenii L.

    2013-02-01

    It is important to identify patients with chronic obstructive pulmonary disease (COPD) and lung cancer in the early stages of the disease. The method of laser opto-acoustic gas analysis, in this case, can act as a promising tool for diagnostics. The material for this study were the gas emission samples collected from patients and healthy volunteers - samples of exhaled air, swabs from teeth and cheeks. A set of material was formed three groups: healthy volunteers, patients with COPD, lung cancer patients. The resulting samples were analyzed by means of laser opto-acoustic gas analyzers: with intracavity location detector (ILPA-1), with extracavity location detector (LGA-2). Presentation of the results in an easy to visual form was performed using the method of elastic maps, based on the principal component analysis. The results of analysis show potentialities of usage of laser optoacoustic spectroscopy application to assess the status of patients with chronic obstructive pulmonary disease and lung cancer.

  4. Optoacoustic response from graphene-based solutions embedded in optical phantoms by using 905-nm high-power diode-laser assemblies

    Science.gov (United States)

    Leggio, Luca; Gallego, Daniel C.; Gawali, Sandeep Babu; Dadrasnia, Ehsan; Sánchez, Miguel; Rodríguez, Sergio; González, Marta; Carpintero, Guillermo; Osiński, Marek; Lamela, Horacio

    2016-03-01

    During the last two decades, optoacoustic imaging has been developed as a novel biomedical imaging technique based on the generation of ultrasound waves by means of laser light. In this work, we investigate the optoacoustic response from graphene-based solutions by using a compact and cost-effective system based on an assembly of several 905-nm pulsed high-power diode lasers coupled to a bundle of 200-μm diameter- core optical fibers. The coupled light is conveyed into a lens system and focused on an absorber consisting of graphene-based nanomaterials (graphene oxide, reduced graphene oxide, and reduced graphene-oxide/gold-nanoparticle hybrid, respectively) diluted in ethanol and hosted in slightly scattering optical phantoms. The high absorption of these graphene-based solutions suggests their potential future use in optoacoustic applications as contrast agents.

  5. Transducers and arrays for underwater sound

    CERN Document Server

    Butler, John L

    2016-01-01

    This improved and updated second edition covers the theory, development, and design of electro-acoustic transducers for underwater applications. This highly regarded text discusses the basics of piezoelectric and magnetostrictive transducers that are currently being used as well as promising new designs. It presents the basic acoustics as well as the specific acoustics data needed in transducer design and evaluation. A broad range of designs of projectors and hydrophones are described in detail along with methods of modeling, evaluation, and measurement. Analysis of projector and hydrophone transducer arrays, including the effects of mutual radiation impedance and numerical models for elements and arrays, are also covered. The book includes new advances in transducer design and transducer materials and has been completely reorganized to be suitable for use as a textbook, as well as a reference or handbook. The new edition contains updates to the first edition, end-of-chapter exercises, and solutions to select...

  6. Mechanical and electrical characteristics of cymbal transducer

    Institute of Scientific and Technical Information of China (English)

    WANG Guangcan; ZHANG Jin; TIAN Wenjie; LIN Guoguang; LIAN Guandong; ZHANG Fuxue

    2005-01-01

    The electromechanical of Cymbal transducer has been researched. Under simple supporting condition, the mechanical and electrical characteristics have been analyzed by using Piezoelectric-elastic theory, Kirchhoff's thin shell vibration theory, Rayleigh-Ritz's theory and equivalent circuit method. The approximate solution and series resonance frequency equation have been given. Under no load, equivalent circuit, correlation parameters of cymbal transducer and the relations between the ratio of cavity depth to radius of Cymbal transducer with resonance frequency, electromechanical coupling coefficient of cymbal transducer have been researched. The best electromechanical coupling coefficient of cymbal transducer has been gained from the results of numerical analysis. It offers a valid theoretical foundation for optimum design of cymbal transducer.

  7. Analog circuit for controlling acoustic transducer arrays

    Energy Technology Data Exchange (ETDEWEB)

    Drumheller, Douglas S. (Cedar Crest, NM)

    1991-01-01

    A simplified ananlog circuit is presented for controlling electromechanical transducer pairs in an acoustic telemetry system. The analog circuit of this invention comprises a single electrical resistor which replaces all of the digital components in a known digital circuit. In accordance with this invention, a first transducer in a transducer pair of array is driven in series with the resistor. The voltage drop across this resistor is then amplified and used to drive the second transducer. The voltage drop across the resistor is proportional and in phase with the current to the transducer. This current is approximately 90 degrees out of phase with the driving voltage to the transducer. This phase shift replaces the digital delay required by the digital control circuit of the prior art.

  8. ERROR COMPENSATOR FOR A POSITION TRANSDUCER

    Science.gov (United States)

    Fowler, A.H.

    1962-06-12

    A device is designed for eliminating the effect of leadscrew errors in positioning machines in which linear motion of a slide is effected from rotary motion of a leadscrew. This is accomplished by providing a corrector cam mounted on the slide, a cam follower, and a transducer housing rotatable by the follower to compensate for all the reproducible errors in the transducer signal which can be related to the slide position. The transducer has an inner part which is movable with respect to the transducer housing. The transducer inner part is coupled to the means for rotating the leadscrew such that relative movement between this part and its housing will provide an output signal proportional to the position of the slide. The corrector cam and its follower perform the compensation by changing the angular position of the transducer housing by an amount that is a function of the slide position and the error at that position. (AEC)

  9. Finite State Transducers Approximating Hidden Markov Models

    CERN Document Server

    Kempe, A

    1999-01-01

    This paper describes the conversion of a Hidden Markov Model into a sequential transducer that closely approximates the behavior of the stochastic model. This transformation is especially advantageous for part-of-speech tagging because the resulting transducer can be composed with other transducers that encode correction rules for the most frequent tagging errors. The speed of tagging is also improved. The described methods have been implemented and successfully tested on six languages.

  10. Introduction to Piezoelectric Actuators and Transducers

    Science.gov (United States)

    2007-11-02

    1 Introduction to Piezoelectric Actuators and Transducers Kenji Uchino, International Center for Actuators and Transducers, Penn State University...REPORT DATE 00 JUN 2003 2. REPORT TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE Introduction to Piezoelectric Actuators and Transducers...now used in various fields. The sound source is made from piezoelectric ceramics as well as magnetostrictive materials. Piezoceramics are generally

  11. Finite Element Modeling for Ultrasonic Transducers (Preprint)

    Science.gov (United States)

    1998-02-27

    virtual prototyping of transducers . Fig. 18 shows a 3D model of a Tonpilz device for low frequency sensing in air. This classical design is usually used...coupled Tonpilz transducer . A thick, flexible matching layer is bonded to the face of the conical head-mass. 7. CONCLUSIONS This paper was intended as a...This is a preprint of a paper published in Proc. SPIE Int. Symp. Medical Imaging 1998, San Diego, Feb 21-27, 1998 Ultrasonic Transducer Engineering

  12. Wideband Single-Crystal Transducer for Bone Characterization

    Science.gov (United States)

    Liang, Yu; Snook, Kevin

    2012-01-01

    The microgravity conditions of space travel result in unique physiological demands on the human body. In particular, the absence of the continual mechanical stresses on the skeletal system that are present on Earth cause the bones to decalcify. Trabecular structure decreases in thickness and increases in spacing, resulting in decreased bone strength and increased risk of injury. Thus, monitoring bone health is a high priority for long-term space travel. A single probe covering all frequency bands of interest would be ideal for such measurements, and this would also minimize storage space and eliminate the complexity of integrating multiple probes. This invention is an ultrasound transducer for the structural characterization of bone. Such characterization measures features of reflected and transmitted ultrasound signals, and correlates these signals with bone structure metrics such as bone mineral density, trabecular spacing, and thickness, etc. The techniques used to determine these various metrics require measurements over a broad range of ultrasound frequencies, and therefore, complete characterization requires the use of several narrowband transducers. This is a single transducer capable of making these measurements in all the required frequency bands. The device achieves this capability through a unique combination of a broadband piezoelectric material; a design incorporating multiple resonator sizes with distinct, overlapping frequency spectra; and a micromachining process for producing the multiple-resonator pattern with common electrode surfaces between the resonators. This device consists of a pattern of resonator bars with common electrodes that is wrapped around a central mandrel such that the radiating faces of the resonators are coplanar and can be simultaneously applied to the sample to be measured. The device operates as both a source and receiver of acoustic energy. It is operated by connection to an electronic system capable of both providing an

  13. A new three-dimensional electromechanical impedance model for an embedded dual-PZT transducer

    Science.gov (United States)

    Wang, Dansheng; Li, Zhi; Zhu, Hongping

    2016-07-01

    In the past twenty years, the electromechanical (EM) impedance technique has been investigated extensively in the mechanical, aviation and civil engineering fields. Many different EM impedance models have been proposed to characterize the interaction between the surface-bonded PZT transducer and the host structure. This paper formulates a new three-dimensional EM impedance model characterizing the interaction between an embedded circle dual-PZT transducer and the host structure based on the effective impedance concept. The proposed model is validated by experimental results from a group of smart cement cubes, in which three circle dual-PZT transducers are embedded respectively. In addition, a new EM impedance measuring method for the dual-PZT transducer is also introduced. In the measuring method, only a common signal generator and an oscilloscope are needed, by which the exciting and receiving voltage signals are obtained respectively. Combined with fast Fourier transform the EM impedance signatures of the dual-PZT transducers are obtained.

  14. Modeling transducer impulse responses for predicting calibrated pressure pulses with the ultrasound simulation program Field II

    DEFF Research Database (Denmark)

    Bæk, David; Jensen, Jørgen Arendt; Willatzen, Morten

    2010-01-01

    FIELD II is a simulation software capable of predicting the field pressure in front of transducers having any complicated geometry. A calibrated prediction with this program is, however, dependent on an exact voltage-to-surface acceleration impulse response of the transducer. Such impulse response...... is not calculated by FIELD II. This work investigates the usability of combining a one-dimensional multilayer transducer modeling principle with the FIELD II software. Multilayer here refers to a transducer composed of several material layers. Measurements of pressure and current from Pz27 piezoceramic disks...... as well as pressure and intensity measurements in front of a 128 element commercial convex medical transducer are compared to the simulations. Results show that the models can predict the pressure from the piezoceramic disks with a root mean square (rms) error of 11.2% to 36.2% with a 2 dB amplitude...

  15. Transducers in medical ultrasound: Part Three. Transducer applications in echocardiology.

    Science.gov (United States)

    Lancée, C T; Daigle, R; Sahn, D J; Thijssen, J M

    1985-09-01

    A comparison is made between phased arrays and mechanical sector scanners in transcutaneous echocardiographic applications. Aspects such as contact area, beam control, side lobes, grating lobes and image quality are discussed in the context of transducer frequency. The incorporation of simultaneous acquisition of Doppler velocity information and display of M-mode signals is considered. Transoesophageal and intraoperative scanning systems for cardiology are also compared, in particular linear arrays, phased arrays and mechanical scanners, and their advantages and disadvantages in relation to the above mentioned aspects are discussed. The general conclusion is that electronic sector scanners may have a considerably improved cost/benefit ratio in the near future and thereby will become the leading systems for echocardiography.

  16. Nonlinear Dynamic Modeling of Langevin-Type Piezoelectric Transducers

    Directory of Open Access Journals (Sweden)

    Nicolás Peréz Alvarez

    2015-11-01

    Full Text Available Langevin transducers are employed in several applications, such as power ultrasound systems, naval hydrophones, and high-displacement actuators. Nonlinear effects can influence their performance, especially at high vibration amplitude levels. These nonlinear effects produce variations in the resonant frequency, harmonics of the excitation frequency, in addition to loss of symmetry in the frequency response and “frequency domain hysteresis”. In this context, this paper presents a simplified nonlinear dynamic model of power ultrasound transducers requiring only two parameters for simulating the most relevant nonlinear effects. One parameter reproduces the changes in the resonance frequency and the other introduces the dependence of the frequency response on the history of the system. The piezoelectric constitutive equations are extended by a linear dependence of the elastic constant on the mechanical displacement amplitude. For introducing the frequency hysteresis, the elastic constant is computed by combining the current value of the mechanical amplitude with the previous state amplitude. The model developed in this work is applied for predicting the dynamic responses of a 26 kHz ultrasonic transducer. The comparison of theoretical and experimental responses, obtained at several input voltages around the tuned frequency, shows a good agreement, indicating that the model can accurately describe the transducer nonlinear behavior.

  17. Teaching a sonographically guided invasive procedure to first-year medical students using a novel finger transducer.

    Science.gov (United States)

    Benninger, Brion; Corbett, Rebecca; Delamarter, Taylor

    2013-04-01

    The exposure to ultrasound technology in medicine is increasing at multiple training levels. Ultrasound transducers have evolved to provide higher-resolution imaging for more accurate structural identification, with few improvements in ease of use. This study investigated a novel finger ultrasound transducer used by first-year medical students conducting structural identification and practicing an invasive procedure. A literature search was conducted on texts, specialty journals, and websites regarding the anatomy of internal jugular and subclavian vein central line placement with sonographic guidance and the use of a finger transducer. First-year medical students performed timed sonographically guided cannulation on the internal jugular and subclavian veins on a phantom torso and identified the internal jugular and subclavian veins on a healthy volunteer using the finger transducer and a conventional transducer. After exposure to both transducers, a survey was taken regarding transducer preference. The literature search revealed no studies comparing finger and classic transducers or sonographically guided central line techniques being conducted by first-year medical students. The students identified and cannulated the internal jugular and subclavian veins using both transducers. Survey results revealed that 70% of the students preferred the finger transducer. This study showed that first-year medical students could interpret sonographic anatomy while conducting a clinical procedure. The finger transducer proved successful in structure identification and was preferred to the classic transducer because of its combined tactile presence. This pilot study of a novel finger transducer showed the benefits of combining palpatory skills with ultrasound technology in teaching first-year medical students to perform invasive procedures.

  18. An Energy-Based Hysteresis Model for Magnetostrictive Transducers

    Science.gov (United States)

    Calkins, F. T.; Smith, R. C.; Flatau, A. B.

    1997-01-01

    This paper addresses the modeling of hysteresis in magnetostrictive transducers. This is considered in the context of control applications which require an accurate characterization of the relation between input currents and strains output by the transducer. This relation typically exhibits significant nonlinearities and hysteresis due to inherent properties of magnetostrictive materials. The characterization considered here is based upon the Jiles-Atherton mean field model for ferromagnetic hysteresis in combination with a quadratic moment rotation model for magnetostriction. As demonstrated through comparison with experimental data, the magnetization model very adequately quantifies both major and minor loops under various operating conditions. The combined model can then be used to accurately characterize output strains at moderate drive levels. The advantages to this model lie in the small number (six) of required parameters and the flexibility it exhibits in a variety of operating conditions.

  19. Hybrid optoacoustic and ultrasound biomicroscopy monitors’ laser-induced tissue modifications and magnetite nanoparticle impregnation

    Science.gov (United States)

    Estrada, Héctor; Sobol, Emil; Baum, Olga; Razansky, Daniel

    2014-12-01

    Tissue modification under laser radiation is emerging as one of the advanced applications of lasers in medicine, with treatments ranging from reshaping and regeneration of cartilage to normalization of the intraocular pressure. Laser-induced structural alterations can be studied using conventional microscopic techniques applied to thin specimen. Yet, development of non-invasive imaging methods for deep tissue monitoring of structural alterations under laser radiation is of great importance, especially for attaining efficient feedback during the procedures. We developed a fast scanning biomicroscopy system that can simultaneously deliver both optoacoustic and pulse-echo ultrasound contrast from intact tissues and show that both modalities allow manifesting the laser-induced changes in cartilage and sclera. Furthermore, images of the sclera samples reveal a crater developing around the center of the laser-irradiated spot as well as a certain degree of thickening within the treated zone, presumably due to pore formation. Finally, we were able to observe selective impregnation of magnetite nanoparticles into the cartilage, thus demonstrating a possible contrast enhancement approach for studying specific treatment effects. Overall, the new imaging approach holds promise for development of noninvasive feedback control systems that could guarantee efficacy and safety of laser-based medical procedures.

  20. Optical clearing of skin enhanced with hyaluronic acid for increased contrast of optoacoustic imaging

    Science.gov (United States)

    Liopo, Anton; Su, Richard; Tsyboulski, Dmitri A.; Oraevsky, Alexander A.

    2016-08-01

    Enhanced delivery of optical clearing agents (OCA) through skin may improve sensitivity of optical and optoacoustic (OA) methods of imaging, sensing, and monitoring. This report describes a two-step method for enhancement of light penetration through skin. Here, we demonstrate that topical application of hyaluronic acid (HA) improves skin penetration of hydrophilic and lipophilic OCA and thus enhances their performance. We examined the OC effect of 100% polyethylene and polypropylene glycols (PPGs) and their mixture after pretreatment by HA, and demonstrated significant increase in efficiency of light penetration through skin. Increased light transmission resulted in a significant increase of OA image contrast in vitro. Topical pretreatment of skin for about 30 min with 0.5% HA in aqueous solution offers effective delivery of low molecular weight OCA such as a mixture of PPG-425 and polyethylene glycol (PEG)-400. The developed approach of pretreatment by HA prior to application of clearing agents (PEG and PPG) resulted in a ˜47-fold increase in transmission of red and near-infrared light and significantly enhanced contrast of OA images.

  1. Optoacoustic tomography in preclinical research: in vivo distribution of highly purified PEG-coated gold nanorods

    Science.gov (United States)

    Su, Richard; Liopo, Anton; Brecht, Hans-Peter; Ermilov, Sergey; Larin, Kirill; Oraevsky, Alexander A.

    2011-07-01

    We report on the optoacoustic (OA) imaging of the whole mouse body using a biocompatible contrast agent - highly purified, pegylated gold nanorods (GNR) - which has strong optical absorption in the near-infrared region and low level of toxicity. In vitro toxicity studies showed no significant change in survival rates of the cultured normal epithelium IEC-6 cells when incubated for 24 hours with up to 1 nM of GNR. In vivo toxicity studies in nude mice showed no pathological changes in liver 1 month after the IV injection of GNR with intra-body concentration around 0.25-0.50 nM. In order to study the enhancement of the OA contrast and accumulation of GNR in different tissues, we performed 3D OA imaging of live nude mice with IV-injected GNR. The enhancement of the OA contrast in comparison with the images of the untreated mice was visible starting 1 hour after the GNR injection. The OA contrast of kidneys, liver, and spleen peaked at about 2-3 days after the administration of the GNR, and then was gradually reducing.

  2. In vivo 3D visualization of peripheral circulatory system using linear optoacoustic array

    Science.gov (United States)

    Ermilov, Sergey A.; Brecht, Hans-Peter; Fronheiser, Matthew P.; Nadvoretsky, Vyacheslav; Su, Richard; Conjusteau, Andre; Oraevsky, Alexander A.

    2010-02-01

    In this work we modified light illumination of the laser optoacoustic (OA) imaging system to improve the 3D visualization of human forearm vasculature. The computer modeling demonstrated that the new illumination design that features laser beams converging on the surface of the skin in the imaging plane of the probe provides superior OA images in comparison to the images generated by the illumination with parallel laser beams. We also developed the procedure for vein/artery differentiation based on OA imaging with 690 nm and 1080 nm laser wavelengths. The procedure includes statistical analysis of the intensities of OA images of the neighboring blood vessels. Analysis of the OA images generated by computer simulation of a human forearm illuminated at 690 nm and 1080 nm resulted in successful differentiation of veins and arteries. In vivo scanning of a human forearm provided high contrast 3D OA image of a forearm skin and a superficial blood vessel. The blood vessel image contrast was further enhanced after it was automatically traced using the developed software. The software also allowed evaluation of the effective blood vessel diameter at each step of the scan. We propose that the developed 3D OA imaging system can be used during preoperative mapping of forearm vessels that is essential for hemodialysis treatment.

  3. Optoacoustic imaging of the prostate: development toward image-guided biopsy.

    Science.gov (United States)

    Yaseen, Mohammad A; Ermilov, Sergey A; Brecht, Hans-Peter; Su, Richard; Conjusteau, André; Fronheiser, Matthew; Bell, Brent A; Motamedi, Massoud; Oraevsky, Alexander A

    2010-01-01

    Optoacoustic (OA) tomography has demonstrated utility in identifying blood-rich malignancies in breast tissue. We describe the development and characterization of a laser OA imaging system for the prostate (LOIS-P). The system consists of a fiber-coupled Q-switched laser operating at 757 nm, a commercial 128-channel ultrasonic probe, a digital signal processor, and software that uses the filtered radial back-projection algorithm for image reconstruction. The system is used to reconstruct OA images of a blood-rich lesion induced in vivo in a canine prostate. OA images obtained in vivo are compared to images acquired using ultrasound, the current gold standard for guiding biopsy of the prostate. Although key structural features such as the urethra could be identified with both imaging techniques, a bloody lesion representing a highly vascularized tumor could only be clearly identified in OA images. The advantages and limitations of both forward and backward illumination modes are also evaluated by collecting OA images of phantoms simulating blood vessels within tissue. System resolution is estimated to be 0.2 mm in the radial direction of the acoustic array. The minimum detectable pressure signal is 1.83 Pa. Our results encourage further development toward a dual-modality OA/ultrasonic system for prostate imaging and image-guided biopsy.

  4. Accelerating image reconstruction in three-dimensional optoacoustic tomography on graphics processing units.

    Science.gov (United States)

    Wang, Kun; Huang, Chao; Kao, Yu-Jiun; Chou, Cheng-Ying; Oraevsky, Alexander A; Anastasio, Mark A

    2013-02-01

    Optoacoustic tomography (OAT) is inherently a three-dimensional (3D) inverse problem. However, most studies of OAT image reconstruction still employ two-dimensional imaging models. One important reason is because 3D image reconstruction is computationally burdensome. The aim of this work is to accelerate existing image reconstruction algorithms for 3D OAT by use of parallel programming techniques. Parallelization strategies are proposed to accelerate a filtered backprojection (FBP) algorithm and two different pairs of projection/backprojection operations that correspond to two different numerical imaging models. The algorithms are designed to fully exploit the parallel computing power of graphics processing units (GPUs). In order to evaluate the parallelization strategies for the projection/backprojection pairs, an iterative image reconstruction algorithm is implemented. Computer simulation and experimental studies are conducted to investigate the computational efficiency and numerical accuracy of the developed algorithms. The GPU implementations improve the computational efficiency by factors of 1000, 125, and 250 for the FBP algorithm and the two pairs of projection/backprojection operators, respectively. Accurate images are reconstructed by use of the FBP and iterative image reconstruction algorithms from both computer-simulated and experimental data. Parallelization strategies for 3D OAT image reconstruction are proposed for the first time. These GPU-based implementations significantly reduce the computational time for 3D image reconstruction, complementing our earlier work on 3D OAT iterative image reconstruction.

  5. Linearization of resistance thermometers and other transducers

    DEFF Research Database (Denmark)

    Diamond, Joseph M.

    1970-01-01

    Given a resistive transducer which responds directly or indirectly to a physical quantity x, it is shown that the relationship may be linearized by linear methods if and only if both the resistance and conductance of the transducer are concave upward as functions of x. This result applies to eith...

  6. 21 CFR 870.2880 - Ultrasonic transducer.

    Science.gov (United States)

    2010-04-01

    ... structures. This device includes phased arrays and two-dimensional scanning transducers. (b) Classification... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Ultrasonic transducer. 870.2880 Section 870.2880...) MEDICAL DEVICES CARDIOVASCULAR DEVICES Cardiovascular Monitoring Devices § 870.2880 Ultrasonic...

  7. Characterization of Ultrasonic Transducers. Measurement report

    DEFF Research Database (Denmark)

    Wilhjelm, Jens Erik

    1996-01-01

    This report contains the first results of a field measurement program for characterizing ultrasonic transducers in use at the Department. Specifically, a number of Panametrics Inc, transducers are characterized by using a 0.1 mm point scatterer as target, which is moved in front of the transdcuer....

  8. Pushdown machines for the macro tree transducer

    NARCIS (Netherlands)

    Engelfriet, Joost; Vogler, Heiko

    1986-01-01

    The macro tree transducer can be considered as a system of recursive function procedures with parameters, where the recursion is on a tree (e.g., the syntax tree of a program). We investigate characterizations of the class of tree (tree-to-string) translations which is induced by macro tree transduc

  9. Micromachined Integrated Transducers for Ultrasound Imaging

    DEFF Research Database (Denmark)

    la Cour, Mette Funding

    The purpose of this project is to develop capacitive micromachined ultrasonic transducers (CMUTs) for medical imaging. Medical ultrasound transducers used today are fabricated using piezoelectric materials and bulk processing. To fabricate transducers capable of delivering a higher imaging...... project and collaboration with a lot of partners to improve medical ultrasound imaging. The focus in this part of the project is to design, fabricate and characterize 1D CMUT arrays. Two versions of 1D transducers are made, one at Stanford University and one at DTU. Electrical and acoustical...... resolution it is however necessary to develop new fabrication methods that allows fabrication of transducer elements with smaller dimensions. By using microfabrication technology it is possible to push the dimensions down and provide higher design flexibility. This project is part of a large ultrasound...

  10. Ultrasound transducer selection in clinical imaging practice.

    Science.gov (United States)

    Szabo, Thomas L; Lewin, Peter A

    2013-04-01

    Many types of medical ultrasound transducers are used in clinical practice. They operate at different center frequencies, have different physical dimensions, footprints, and shapes, and provide different image formats. However, little information is available about which transducers are most appropriate for a given application, and the purpose of this article is to address this deficiency. Specifically, the relationship between the transducer, imaging format, and clinical applications is discussed, and systematic selection criteria that allow matching of transducers to specific clinical needs are presented. These criteria include access to and coverage of the region of interest, maximum scan depth, and coverage of essential diagnostic modes required to optimize a patient's diagnosis. Three comprehensive figures organize and summarize the imaging planes, scanning modes, and types of diagnostic transducers to facilitate their selection in clinical diagnosis.

  11. An NLRA Transducer for Dual Use Bone Conduction Audio and Haptic Communication. Summary Report

    Science.gov (United States)

    2016-12-30

    component. Initially developed to enable the most precise haptic communication components, NLRA technology has the potential to create a combined...transducer core capable of both precise haptic communication and high fidelity bone conduction audio. The transducer design leverages Micro-Multilayer...Its ideal use is as a component of a head-mounted communication system for CBRNE and Special Operations Forces exposed to many simultaneous sensory

  12. Electrical modeling of dielectric elastomer stack transducers

    Science.gov (United States)

    Haus, Henry; Matysek, Marc; Moessinger, Holger; Flittner, Klaus; Schlaak, Helmut F.

    2013-04-01

    Performance of dielectric elastomer transducers (DEST) depends on mechanical and electrical parameters. For designing DEST it is therefore necessary to know the influences of these parameters on the overall performance. We show an electrical equivalent circuit valid for a transducer consisting of multiple layers and derive the electrical parameters of the circuit depending on transducers geometry and surface resistivity of the electrodes. This allows describing the DESTs dynamic behavior as a function of fabrication (layout, sheet and interconnection resistance), material (breakdown strength, permittivity) and driving (voltage) parameters. Using this electrical model transfer function and cut-off frequency are calculated, describing the influence of transducer capacitance, resistance and driving frequency on the achievable actuation deflection. Furthermore non ideal boundary effects influencing the capacitance value of the transducer are investigated by an electrostatic simulation and limits for presuming a simple plate capacitor model for calculating the transducer capacitance are derived. Results provide the plate capacitor model is a valid assumption for typical transducer configurations but for certain aspect ratios of electrode dimensions to dielectric thickness -- arising e.g. in the application of tactile interfaces -- the influence of boundary effects is to be considered.

  13. Modeling of functionally graded piezoelectric ultrasonic transducers.

    Science.gov (United States)

    Rubio, Wilfredo Montealegre; Buiochi, Flávio; Adamowski, Julio Cezar; Silva, Emílio Carlos Nelli

    2009-05-01

    The application of functionally graded material (FGM) concept to piezoelectric transducers allows the design of composite transducers without interfaces, due to the continuous change of property values. Thus, large improvements can be achieved, as reduction of stress concentration, increasing of bonding strength, and bandwidth. This work proposes to design and to model FGM piezoelectric transducers and to compare their performance with non-FGM ones. Analytical and finite element (FE) modeling of FGM piezoelectric transducers radiating a plane pressure wave in fluid medium are developed and their results are compared. The ANSYS software is used for the FE modeling. The analytical model is based on FGM-equivalent acoustic transmission-line model, which is implemented using MATLAB software. Two cases are considered: (i) the transducer emits a pressure wave in water and it is composed of a graded piezoceramic disk, and backing and matching layers made of homogeneous materials; (ii) the transducer has no backing and matching layer; in this case, no external load is simulated. Time and frequency pressure responses are obtained through a transient analysis. The material properties are graded along thickness direction. Linear and exponential gradation functions are implemented to illustrate the influence of gradation on the transducer pressure response, electrical impedance, and resonance frequencies.

  14. Seismic transducer modeling using ABAQUS

    Energy Technology Data Exchange (ETDEWEB)

    Stephen R. Novascone

    2004-05-01

    A seismic transducer, known as an orbital vibrator, consists of a rotating imbalance driven by an electric motor. When suspended in a liquid-filled wellbore, vibrations of the device are coupled to the surrounding geologic media. In this mode, an orbital vibrator can be used as an efficient rotating dipole source for seismic imaging. Alternately, the motion of an orbital vibrator is affected by the physical properties of the surrounding media. From this point of view, an orbital vibrator can be used as a stand-alone sensor. The reaction to the surroundings can be sensed and recorded by geophones inside the orbital vibrator. These reactions are a function of the media’s physical properties such as modulus, damping, and density, thereby identifying the rock type. This presentation shows how the orbital vibrator and surroundings were modeled with an ABAQUS acoustic FEM. The FEM is found to compare favorably with theoretical predictions. A 2D FEM and analytical model are compared to an experimental data set. Each model compares favorably with the data set.

  15. Wideband Single-Crystal Transducer for Bone Characterization

    Science.gov (United States)

    Liang, Yu; Snook, Kevin

    2012-01-01

    The microgravity conditions of space travel result in unique physiological demands on the human body. In particular, the absence of the continual mechanical stresses on the skeletal system that are present on Earth cause the bones to decalcify. Trabecular structure decreases in thickness and increases in spacing, resulting in decreased bone strength and increased risk of injury. Thus, monitoring bone health is a high priority for long-term space travel. A single probe covering all frequency bands of interest would be ideal for such measurements, and this would also minimize storage space and eliminate the complexity of integrating multiple probes. This invention is an ultrasound transducer for the structural characterization of bone. Such characterization measures features of reflected and transmitted ultrasound signals, and correlates these signals with bone structure metrics such as bone mineral density, trabecular spacing, and thickness, etc. The techniques used to determine these various metrics require measurements over a broad range of ultrasound frequencies, and therefore, complete characterization requires the use of several narrowband transducers. This is a single transducer capable of making these measurements in all the required frequency bands. The device achieves this capability through a unique combination of a broadband piezoelectric material; a design incorporating multiple resonator sizes with distinct, overlapping frequency spectra; and a micromachining process for producing the multiple-resonator pattern with common electrode surfaces between the resonators. This device consists of a pattern of resonator bars with common electrodes that is wrapped around a central mandrel such that the radiating faces of the resonators are coplanar and can be simultaneously applied to the sample to be measured. The device operates as both a source and receiver of acoustic energy. It is operated by connection to an electronic system capable of both providing an

  16. Hybrid piezoelectric energy harvesting transducer system

    Science.gov (United States)

    Xu, Tian-Bing (Inventor); Jiang, Xiaoning (Inventor); Su, Ji (Inventor); Rehrig, Paul W. (Inventor); Hackenberger, Wesley S. (Inventor)

    2008-01-01

    A hybrid piezoelectric energy harvesting transducer system includes: (a) first and second symmetric, pre-curved piezoelectric elements mounted separately on a frame so that their concave major surfaces are positioned opposite to each other; and (b) a linear piezoelectric element mounted separately on the frame and positioned between the pre-curved piezoelectric elements. The pre-curved piezoelectric elements and the linear piezoelectric element are spaced from one another and communicate with energy harvesting circuitry having contact points on the frame. The hybrid piezoelectric energy harvesting transducer system has a higher electromechanical energy conversion efficiency than any known piezoelectric transducer.

  17. Piezoelectric pressure transducer technique for oxidizing atmospheres

    Science.gov (United States)

    Roberts, Ted A.; Burton, Rodney L.

    1992-07-01

    The diaphragm sensing tip of a high-speed piezoelectric pressure transducer can be destroyed when measuring transient impulse pressures in hot oxidizing atmospheres, e.g., oxygen at 3000 K and 34 atm for times of tens of milliseconds. A technique is presented to preserve the transducer under these conditions, which uses a protective layer of 0.025-0.050-mm-thick brass foil, held in place with double-sided tape. The integrity of the transducer is preserved, and the response time to a shock wave is increased from 1 to 2-6/microsec using the technique.

  18. Nano-structural characteristics of carbon nanotube-polymer composite films for high-amplitude optoacoustic generation

    Science.gov (United States)

    Baac, Hyoung Won; Ok, Jong G.; Lee, Taehwa; Jay Guo, L.

    2015-08-01

    We demonstrate nano-structural characteristics of carbon nanotube (CNT)-polydimethylsiloxane (PDMS) composite films that can be used as highly efficient and robust ultrasound transmitters for diagnostic and therapeutic applications. An inherent architecture of the nano-composite provides unique thermal, optical, and mechanical properties that are accommodated not just for efficient energy conversion but also for extraordinary robustness against pulsed laser ablation. First, we explain a thermoacoustic transfer mechanism within the nano-composite. CNT morphologies are examined to determine a suitable arrangement for heat transfer to the surrounding PDMS. Next, we introduce an approach to enhance optical extinction of the composite films, which uses shadowed deposition of a thin Au layer through an as-grown CNT network. Finally, the transmitter robustness is quantified in terms of laser-induced damage threshold. This reveals that the CNT-PDMS films can withstand an order-of-magnitude higher optical fluence (and extinction) than a Cr film used as a reference. Such robustness is crucial to increase the maximum-available optical energy for optoacoustic excitation and pressure generation. All of these structure-originated characteristics manifest the CNT-PDMS composite films as excellent optoacoustic transmitters for high-amplitude and high-frequency ultrasound generation.

  19. Optoacoustic spectroscopy for real-time monitoring of strongly light-absorbing solutions in applications to analytical chemistry.

    Science.gov (United States)

    Filimonova, Tatyana A; Volkov, Dmitry S; Proskurnin, Mikhail A; Pelivanov, Ivan M

    2013-12-01

    An optoacoustic technique for solutions of strongly light-absorbing analytes at 0.1-0.01 mol l(-1) is proposed. The technique is based on the wide-band forward mode detection of temporal profiles of laser-generated ultrasonic pulses (optoacoustic signals). The leading edge of the signal repeats the distribution of the laser fluence in the medium, which makes it possible to determine its optical absorption and investigate its dynamics during a reaction. The range of light-absorption coefficients starts from 1 to 5 and reaches 10(4) to 10(5) cm(-1). The determination of iron(II) as ferroin shows the possibility of probing 0.1 mol l(-1) of iron(II), which was not previously achieved for this reaction by optical spectroscopy. To further prove the concept, kinetic measurements for ferroin decomposition at the level of 0.1 mol l(-1) and at high pHs are performed. The results are compared with spectrophotometry at lower concentrations and show good reproducibility and accuracy of kinetic constants.

  20. Nano-structural characteristics of carbon nanotube-polymer composite films for high-amplitude optoacoustic generation.

    Science.gov (United States)

    Baac, Hyoung Won; Ok, Jong G; Lee, Taehwa; Guo, L Jay

    2015-09-14

    We demonstrate nano-structural characteristics of carbon nanotube (CNT)-polydimethylsiloxane (PDMS) composite films that can be used as highly efficient and robust ultrasound transmitters for diagnostic and therapeutic applications. An inherent architecture of the nano-composite provides unique thermal, optical, and mechanical properties that are accommodated not just for efficient energy conversion but also for extraordinary robustness against pulsed laser ablation. First, we explain a thermoacoustic transfer mechanism within the nano-composite. CNT morphologies are examined to determine a suitable arrangement for heat transfer to the surrounding PDMS. Next, we introduce an approach to enhance optical extinction of the composite films, which uses shadowed deposition of a thin Au layer through an as-grown CNT network. Finally, the transmitter robustness is quantified in terms of laser-induced damage threshold. This reveals that the CNT-PDMS films can withstand an order-of-magnitude higher optical fluence (and extinction) than a Cr film used as a reference. Such robustness is crucial to increase the maximum-available optical energy for optoacoustic excitation and pressure generation. All of these structure-originated characteristics manifest the CNT-PDMS composite films as excellent optoacoustic transmitters for high-amplitude and high-frequency ultrasound generation.

  1. Impact of nonstationary optical illumination on image reconstruction in optoacoustic tomography.

    Science.gov (United States)

    Lou, Yang; Wang, Kun; Oraevsky, Alexander A; Anastasio, Mark A

    2016-12-01

    Optoacoustic tomography (OAT), also known as photoacoustic tomography, is a rapidly emerging hybrid imaging technique that possesses great potential for a wide range of biomedical imaging applications. In OAT, a laser is employed to illuminate the tissue of interest and acoustic signals are produced via the photoacoustic effect. From these data, an estimate of the distribution of the absorbed optical energy density within the tissue is reconstructed, referred to as the object function. This quantity is defined, in part, by the distribution of light fluence within the tissue that is established by the laser source. When performing three-dimensional imaging of large objects, such as a female human breast, it can be difficult to achieve a relatively uniform coverage of light fluence within the volume of interest when the position of the laser source is fixed. To circumvent this, researchers have proposed illumination schemes in which the relative position of the laser source and ultrasound probe is fixed, and both are rotated together to acquire a tomographic dataset. A problem with this rotating-illumination scheme is that the tomographic data are inconsistent; namely, the acoustic data recorded at each tomographic view angle (i.e., probe position) are produced by a distinct object function. In this work, the impact of this data inconsistency on image reconstruction accuracy is investigated systematically. This is accomplished by use of computer-simulation studies and application of mathematical results from the theory of microlocal analysis. These studies specify the set of image discontinuities that can be stably reconstructed with a nonstationary optical illumination setup. The study also includes a comparison of the ability of iterative and analytic image reconstruction methods to mitigate artifacts attributable to the data inconsistency.

  2. All-optical optoacoustic microscopy system based on probe beam deflection technique

    Science.gov (United States)

    Maswadi, Saher M.; Tsyboulskic, Dmitri; Roth, Caleb C.; Glickman, Randolph D.; Beier, Hope T.; Oraevsky, Alexander A.; Ibey, Bennett L.

    2016-03-01

    It is difficult to achieve sub-micron resolution in backward mode OA microscopy using conventional piezoelectric detectors, because of wavefront distortions caused by components placed in the optical path, between the sample and the objective lens, that are required to separate the acoustic wave from the optical beam. As an alternate approach, an optoacoustic microscope (OAM) was constructed using the probe beam deflection technique (PBDT) to detect laserinduced acoustic signals. The all-optical OAM detects laser-generated pressure waves using a probe beam passing through a coupling medium, such as water, filling the space between the microscope objective lens and sample. The acoustic waves generated in the sample propagate through the coupling medium, causing transient changes in the refractive index that deflect the probe beam. These deflections are measured with a high-speed, balanced photodiode position detector. The deflection amplitude is directly proportional to the magnitude of the acoustic pressure wave, and provides the data required for image reconstruction. The sensitivity of the PBDT detector expressed as noise equivalent pressure was 12 Pa, comparable to that of existing high-performance ultrasound detectors. Because of the unimpeded working distance, a high numerical aperture objective lens, i.e. NA = 1, was employed in the OAM to achieve near diffraction-limited lateral resolution of 0.5 μm at 532nm. The all-optical OAM provides several benefits over current piezoelectric detector-based systems, such as increased lateral and axial resolution, higher sensitivity, robustness, and potentially more compatibility with multimodal instruments.

  3. Multispectral opto-acoustic tomography (MSOT) of the brain and glioblastoma characterization.

    Science.gov (United States)

    Burton, Neal C; Patel, Manishkumar; Morscher, Stefan; Driessen, Wouter H P; Claussen, Jing; Beziere, Nicolas; Jetzfellner, Thomas; Taruttis, Adrian; Razansky, Daniel; Bednar, Bohumil; Ntziachristos, Vasilis

    2013-01-15

    Brain research depends strongly on imaging for assessing function and disease in vivo. We examine herein multispectral opto-acoustic tomography (MSOT), a novel technology for high-resolution molecular imaging deep inside tissues. MSOT illuminates tissue with light pulses at multiple wavelengths and detects the acoustic waves generated by the thermoelastic expansion of the environment surrounding absorbing molecules. Using spectral unmixing analysis of the data collected, MSOT can then differentiate the spectral signatures of oxygenated and deoxygenated hemoglobin and of photo-absorbing agents and quantify their concentration. By being able to detect absorbing molecules up to centimeters deep in the tissue it represents an ideal modality for small animal brain imaging, simultaneously providing anatomical, hemodynamic, functional, and molecular information. In this work we examine the capacity of MSOT in cross-sectional brain imaging of mice. We find unprecedented optical imaging performance in cross-sectional visualization of anatomical and physiological parameters of the mouse brain. For example, the potential of MSOT to characterize ischemic brain areas was demonstrated through the use of a carbon dioxide challenge. In addition, indocyanine green (ICG) was injected intravenously, and the kinetics of uptake and clearance in the vasculature of the brain was visualized in real-time. We further found that multiparameter, multispectral imaging of the growth of U87 tumor cells injected into the brain could be visualized through the intact mouse head, for example through visualization of deoxygenated hemoglobin in the growing tumor. We also demonstrate how MSOT offers several compelling features for brain research and allows time-dependent detection and quantification of brain parameters that are not available using other imaging methods without invasive procedures. Copyright © 2012. Published by Elsevier Inc.

  4. Beam Profile Improvement of a High-Power Diode Laser Stack for Optoacoustic Applications

    Science.gov (United States)

    Sánchez, Miguel; Rodríguez, Sergio; Leggio, Luca; Gawali, Sandeep; Gallego, Daniel; Lamela, Horacio

    2017-04-01

    Recent advances in high-power diode lasers (HPDLs) technology allow their use as potential sources for optoacoustic (OA) applications, due to their high repetition rates (a few kHz), low costs and sizes. However, some OA applications require pulse energies in the order of mJ that cannot be provided by the only HPDLs (several μJ). The employment of diode laser bars (DLBs) and stacks (DLSs) significantly increases the energy per pulse up to several mJ, but they require more optical elements for collimation in fast and slow axes. In this work, we show an 808 nm DLS emitting optical nanosecond pulses with currents of ˜ 200 A and supplied by a customized current driver. We only collimate the beam in the fast axis by disposing the core of 200 μm optical fibers as collimating lenses along each bar of the stack, and we discuss the improvement of the beam profile. The results demonstrate that the beam profile is notably improved with the optical fiber lenses, and a 6.4 mm × 4.3 mm light spot is obtained by using a conventional focusing lens. Measurements report a total energy per pulse of 630 μJ in the spot, considering a pulse width of 850 ns and a repetition rate of 1 kHz. Finally, we focus the light spot into an absorbing inclusion (graphene oxide) hosted in a semi-transparent phantom to generate and detect high OA signals ({˜ }355 mV_{pp}). The results achieved demonstrate the capability of our DLS system to be applied in multispectral OA systems with final application in OA endoscopy and microscopy.

  5. Portable high precision pressure transducer system

    Science.gov (United States)

    Piper, T. C.; Morgan, J. P.; Marchant, N. J.; Bolton, S. M.

    A high precision pressure transducer system for checking the reliability of a second pressure transducer system used to monitor the level of a fluid confined in a holding tank is presented. Since the response of the pressure transducer is temperature sensitive, it is continually housed in a battery powered oven which is configured to provide a temperature stable environment at specified temperature for an extended period of time. Further, a high precision temperature stabilized oscillator and counter are coupled to a single board computer to accurately determine the pressure transducer oscillation frequency and convert it to an applied pressure. All of the components are powered by the batteries which during periods of availability of line power are charged by an on-board battery charger. The pressure readings outputs are transmitted to a line printer and a vacuum fluorescent display.

  6. Conductometric transducers for enzyme-based biosensors.

    Science.gov (United States)

    Mikkelsen, S R; Rechnitz, G A

    1989-08-01

    The use of alternating current conductometric transducers in biosensing devices has been investigated for urea and D-amino acid sensors using the enzyme systems urease and D-amino acid oxidase/catalase. Transducers with copper and platinum electrodes were constructed and characterized, and two enzyme immobilization methods were tested. Detection limits of 1 x 10(-6)M and linear ranges of 2 orders of magnitude were routinely achieved for these model sensors with enzymes covalently immobilized on collagen films.

  7. Performance of Honeywell silicon pressure transducers

    Digital Repository Service at National Institute of Oceanography (India)

    VijayKumar, K.; Joseph, A.; Desai, R.G.P.; Nagvekar, S.; Prabhudesai, S.; Damodaran, V.

    strain gauge, semiconductor strain gauge, and quartz crystal beam. In this paper we examine the laboratory performance of a few temperature-compensated Honeywell silicon strain gauge pressure transducers based on their static calibration. 2. Silicon... Thin-Diaphragm Strain Gauge Pressure Transducer Although semiconductor materials such as germanium and silicon exhibit substantial temperature-dependence, they possess pressure-sensitivities several times that of metallic strain gauges. Silicon...

  8. Piezoelectric and Electrostrictive Materials for Transducer Applications.

    Science.gov (United States)

    1985-05-01

    Structure Ferroelastic Silicates" Alan Hain, Jr. B.S. Engineering Science, May 1984. "New Bimorph Structures with High Flexural Resonance Frequency" Eric ...Applications of PZT/Polymer Composite Materials,’ Ferroelectrics 39, 1245-1248 (1981). 22. Erikson , K.R. ’Tone-Burst Testing of Pulse-Echo Transducer...burst pulse-echo method described by Erikson [2]. A schematic diagram of the experimental set up is shown in Figure 1. The composite transducer was

  9. Design considerations for piezoelectric polymer ultrasound transducers.

    Science.gov (United States)

    Brown, L F

    2000-01-01

    Much work has been published on the design of ultrasound transducers using piezoelectric ceramics, but a great deal of this work does not apply when using the piezoelectric polymers because of their unique electrical and mechanical properties. The purpose of this paper is to review and present new insight into seven important considerations for the design of active piezoelectric polymer ultrasound transducers: piezoelectric polymer materials selection, transducer construction and packaging requirements, materials characterization and modeling, film thickness and active area design, electroding selection, backing material design, and front protection/matching layer design. Besides reviewing these design considerations, this paper also presents new insight into the design of active piezoelectric polymer ultrasonic transducers. The design and fabrication of an immersible ultrasonic transducer, which has no adhesive layer between the active element and backing layer, is included. The transducer features direct deposition of poly(vinylidene fluoride-trifluoroethylene) [P(VDF-TrFE)] copolymer onto an insulated aluminum backing substrate. Pulse-echo tests indicated a minimum insertion loss of 37 dB and -6 dB bandwidth of 9.8 to 22 MHz (71%). The use of polymer wear-protection/quarter-wave matching layers is also discussed. Test results on a P(VDF-TrFE) transducer showed that a Mylar/sup TM/ front layer provided a slight increase in pulse-echo amplitude of 15% (or 1.2 dB) and an increase in -6 dB pulse-echo fractional bandwidth from 86 to 95%. Theoretical derivations are reported for optimizing the active area of the piezoelectric polymer element for maximum power transfer at resonance. These derivations are extended to the special case for a low profile (i.e., thin) shielded transducer. A method for modeling the non-linear loading effects of a commercial pulser-receiver is also included.

  10. Comparison of piezoresistive and capacitive ultrasonic transducers

    Science.gov (United States)

    Neumann, John J.; Greve, David W.; Oppenheim, Irving J.

    2004-07-01

    MEMS ultrasonic transducers for flaw detection have heretofore been built as capacitive diaphragm-type devices. A diaphragm forms a moveable electrode, placed at a short gap from a stationary electrode, and diaphragm movement has been detected by capacitance change. Although several research teams have successfully demonstrated that technology, the detection of capacitance change is adversely affected by stray and parasitic capacitances, limiting the sensitivity of such transducers and typically requiring relatively large diaphragm areas. We describe the design and fabrication of what to our knowledge is the first CMOS-MEMS ultrasonic phased array transducer using piezoresistive strain sensing. Piezoresistors have been patterned within the diaphragms, and diaphragm movement creates bending strain which is detected by a bridge circuit, for which conductor losses will be less significant. The prospective advantage of such piezoresistive transducers is that sufficient sensitivity may be achieved with very small diaphragms. We compare transducer response under fluid-coupled ultrasonic excitation and report the experimental gauge factor for the piezoresistors. We also discuss the phased array performance of the transducer in sensing the direction of an incoming wave.

  11. Iterative reconstruction of the transducer surface velocity.

    Science.gov (United States)

    Alles, Erwin; van Dongen, Koen

    2013-05-01

    Ultrasound arrays used for medical imaging consist of many elements placed closely together. Ideally, each element vibrates independently. However, because of mechanical coupling, crosstalk between neighboring elements may occur. To quantify the amount of crosstalk, the transducer velocity distribution should be measured. In this work, a method is presented to reconstruct the velocity distribution from far-field pressure field measurements acquired over an arbitrary surface. The distribution is retrieved from the measurements by solving an integral equation, derived from the Rayleigh integral of the first kind, using a conjugate gradient inversion scheme. This approach has the advantages that it allows for arbitrary transducer and pressure field measurement geometries, as well as the application of regularization techniques. Numerical experiments show that measuring the pressure field along a hemisphere enclosing the transducer yields significantly more accurate reconstructions than measuring along a parallel plane. In addition, it is shown that an increase in accuracy is achieved when the assumption is made that all points on the transducer surface vibrate in phase. Finally, the method has been tested on an actual transducer with an active element of 700 × 200 μm which operates at a center frequency of 12.2 MHz. For this transducer, the velocity distribution has been reconstructed accurately to within 50 μm precision from pressure measurements at a distance of 1.98 mm (=16λ0) using a 200-μm-diameter needle hydrophone.

  12. [Inductance transducers for borderline localization of metallic foreign bodies].

    Science.gov (United States)

    Pudov, V I; Reutov, Iu Ia; Korotkikh, S A

    1996-01-01

    The paper outlines the advantages and disadvantages of a ferroprobe inductance transducer used in the borderline localization of a foreign ferromagnetic body. To eliminate the ferroprobe transducer-inherent disadvantages, a whirl-current inductance transducer has been developed. The transducer localizes a foreign nonferromagnetic and ferromagnetic body in its borderline localization in the eye and in the whole body.

  13. 21 CFR 870.2890 - Vessel occlusion transducer.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Vessel occlusion transducer. 870.2890 Section 870... transducer. (a) Identification. A vessel occlusion transducer is a device used to provide an electrical..., sound, and ultrasonic transducers. (b) Classification. Class II (performance standards). ...

  14. 21 CFR 870.2850 - Extravascular blood pressure transducer.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Extravascular blood pressure transducer. 870.2850... blood pressure transducer. (a) Identification. An extravascular blood pressure transducer is a device... proximal end of the transducer is connected to a pressure monitor that produces an analog or digital...

  15. 21 CFR 870.2060 - Transducer signal amplifier and conditioner.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Transducer signal amplifier and conditioner. 870... Transducer signal amplifier and conditioner. (a) Identification. A transducer signal amplifier and conditioner is a device used to provide the excitation energy for the transducer and to amplify or condition...

  16. 21 CFR 870.2860 - Heart sound transducer.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Heart sound transducer. 870.2860 Section 870.2860...) MEDICAL DEVICES CARDIOVASCULAR DEVICES Cardiovascular Monitoring Devices § 870.2860 Heart sound transducer. (a) Identification. A heart sound transducer is an external transducer that exhibits a change in...

  17. Some Strip Contributions to Transducer Design and Analysis

    Science.gov (United States)

    1989-04-28

    19951116 110 14. SUBJECT TERMS Sonar transducers , Tonpilz transducers , ku-mode transducers , 15. NUMBER OF PAGES Piezoelectric ceramic, Ceramic stack...PRACTICAL ILLUSTRATIONS OF THE SGM ANALYSIS ................. 149 B.1 THE IN-WATER SGM RESULTS OF THE STR-330A TONPILZ TRANSDUCER M O D E L...150 B.2 THE IN-WATER SGM RESULTS OF THE STR-330A TONPILZ TRANSDUCER MODEL: VARIABLE mH, FIXED mTAND com

  18. High temperature, high power piezoelectric composite transducers.

    Science.gov (United States)

    Lee, Hyeong Jae; Zhang, Shujun; Bar-Cohen, Yoseph; Sherrit, Stewart

    2014-08-08

    Piezoelectric composites are a class of functional materials consisting of piezoelectric active materials and non-piezoelectric passive polymers, mechanically attached together to form different connectivities. These composites have several advantages compared to conventional piezoelectric ceramics and polymers, including improved electromechanical properties, mechanical flexibility and the ability to tailor properties by using several different connectivity patterns. These advantages have led to the improvement of overall transducer performance, such as transducer sensitivity and bandwidth, resulting in rapid implementation of piezoelectric composites in medical imaging ultrasounds and other acoustic transducers. Recently, new piezoelectric composite transducers have been developed with optimized composite components that have improved thermal stability and mechanical quality factors, making them promising candidates for high temperature, high power transducer applications, such as therapeutic ultrasound, high power ultrasonic wirebonding, high temperature non-destructive testing, and downhole energy harvesting. This paper will present recent developments of piezoelectric composite technology for high temperature and high power applications. The concerns and limitations of using piezoelectric composites will also be discussed, and the expected future research directions will be outlined.

  19. High Temperature, High Power Piezoelectric Composite Transducers

    Directory of Open Access Journals (Sweden)

    Hyeong Jae Lee

    2014-08-01

    Full Text Available Piezoelectric composites are a class of functional materials consisting of piezoelectric active materials and non-piezoelectric passive polymers, mechanically attached together to form different connectivities. These composites have several advantages compared to conventional piezoelectric ceramics and polymers, including improved electromechanical properties, mechanical flexibility and the ability to tailor properties by using several different connectivity patterns. These advantages have led to the improvement of overall transducer performance, such as transducer sensitivity and bandwidth, resulting in rapid implementation of piezoelectric composites in medical imaging ultrasounds and other acoustic transducers. Recently, new piezoelectric composite transducers have been developed with optimized composite components that have improved thermal stability and mechanical quality factors, making them promising candidates for high temperature, high power transducer applications, such as therapeutic ultrasound, high power ultrasonic wirebonding, high temperature non-destructive testing, and downhole energy harvesting. This paper will present recent developments of piezoelectric composite technology for high temperature and high power applications. The concerns and limitations of using piezoelectric composites will also be discussed, and the expected future research directions will be outlined.

  20. Development and Translation of Hybrid Optoacoustic/Ultrasonic Tomography for Early Breast Cancer Detection

    Science.gov (United States)

    2015-09-01

    acoustically absorbing media was modeled by three coupled first-order partial differential equations [47]: Fig. 1. Schematic of a USCT system with a...be developed to account for out-of-plane scattering, the transducer finite aperture size effect, acoustic absorption, as well as other physical fac...art. no. 692009. [47] B. E. Treeby, E. Z. Zhang, and B. T. Cox, “Photoacoustic tomogra- phy in absorbing acoustic media using time reversal

  1. Two-dimensional refractive index modulation by phased array transducers in acousto-optic deflectors.

    Science.gov (United States)

    Wang, Tiansi; Zhang, Chong; Aleksov, Aleksandar; Salama, Islam; Kar, Aravinda

    2017-01-20

    Acousto-optic deflectors are photonic devices that are used for scanning high-power laser beams in advanced microprocessing applications such as marking and direct writing. The operation of conventional deflectors mostly relies on one-dimensional sinusoidal variation of the refractive index in an acousto-optic medium. Sometimes static phased array transducers, such as step configuration or planar configuration transducer architecture, are used to tilt the index modulation planes for achieving higher performance and higher resolution than a single transducer AO device. However, the index can be modulated in two dimensions, and the modulation plane can be tilted arbitrarily by creating dynamic phase gratings in the medium using phased array transducers. This type of dynamic two-dimensional acousto-optic deflector can provide better performance using, for example, a large deflection angle and high diffraction efficiency. This paper utilizes an ultrasonic beam steering approach to study the two-dimensional strain-induced index modulation due to the photoelastic effect. The modulation is numerically simulated, and the effects of various parameters, such as the operating radiofrequency of the transducers, the ultrasonic beam steering angle, and different combinations of pressure on each element of the transducer array, are demonstrated.

  2. Vaccinia virus-mediated melanin production allows MR and optoacoustic deep tissue imaging and laser-induced thermotherapy of cancer.

    Science.gov (United States)

    Stritzker, Jochen; Kirscher, Lorenz; Scadeng, Miriam; Deliolanis, Nikolaos C; Morscher, Stefan; Symvoulidis, Panagiotis; Schaefer, Karin; Zhang, Qian; Buckel, Lisa; Hess, Michael; Donat, Ulrike; Bradley, William G; Ntziachristos, Vasilis; Szalay, Aladar A

    2013-02-26

    We reported earlier the delivery of antiangiogenic single chain antibodies by using oncolytic vaccinia virus strains to enhance their therapeutic efficacy. Here, we provide evidence that gene-evoked production of melanin can be used as a therapeutic and diagnostic mediator, as exemplified by insertion of only one or two genes into the genome of an oncolytic vaccinia virus strain. We found that produced melanin is an excellent reporter for optical imaging without addition of substrate. Melanin production also facilitated deep tissue optoacoustic imaging as well as MRI. In addition, melanin was shown to be a suitable target for laser-induced thermotherapy and enhanced oncolytic viral therapy. In conclusion, melanin as a mediator for thermotherapy and reporter for different imaging modalities may soon become a versatile alternative to replace fluorescent proteins also in other biological systems. After ongoing extensive preclinical studies, melanin overproducing oncolytic virus strains might be used in clinical trials in patients with cancer.

  3. Detection, numerical simulation and approximate inversion of optoacoustic signals generated in multi-layered PVA hydrogel based tissue phantoms

    CERN Document Server

    Blumenröther, E; Wollweber, M; Roth, B

    2016-01-01

    In this article we characterize optoacoustic signals generated from layered tissue phantoms via short laser pulses by experimental and numerical means. In particular, we consider the case where scattering is effectively negligible and the absorbed energy density follows Beer-Lambert's law, i.e. is characterized by an exponential decay within the layers and discontinuities at interfaces. We complement experiments on samples with multiple layers, where the material properties are known a priori, with numerical calculations for a pointlike detector, tailored to suit our experimental setup. Experimentally, we characterize the acoustic signal observed by a piezoelectric detector in the acoustic far-field in backward mode and we discuss the implication of acoustic diffraction on our measurements. We further attempt an inversion of an OA signal in the far-field approximation.

  4. Detection, numerical simulation and approximate inversion of optoacoustic signals generated in multi-layered PVA hydrogel based tissue phantoms

    Directory of Open Access Journals (Sweden)

    E. Blumenröther

    2016-12-01

    Full Text Available Optoacoustic (OA measurements can not only be used for imaging purposes but as a more general tool to “sense” physical characteristics of biological tissue, such as geometric features and intrinsic optical properties. In order to pave the way for a systematic model-guided analysis of complex objects we devised numerical simulations in accordance with the experimental measurements. We validate our computational approach with experimental results observed for layered polyvinyl alcohol hydrogel samples, using melanin as the absorbing agent. Experimentally, we characterize the acoustic signal observed by a piezoelectric detector in the acoustic far-field in backward mode and we discuss the implication of acoustic diffraction on our measurements. We further attempt an inversion of an OA signal in the far-field approximation.

  5. Implications of Dynamic Pressure Transducer Mounting Variations on Measurements in Pyrotechnic Test Apparatus

    Science.gov (United States)

    Dibbern, Andreas; Crisafulli, Jeffrey; Hagopia, Michael; McDougle, Stephen H.; Saulsberry, Regor L.

    2009-01-01

    Accurate dynamic pressure measurements are often difficult to make within small pyrotechnic devices, and transducer mounting difficulties can cause data anomalies that lead to erroneous conclusions. Delayed initial pressure response followed by data ringing has been observed when using miniaturized pressure transducer mounting adapters required to interface transducers to small test chambers. This delayed pressure response and ringing, combined with a high data acquisition rate, has complicated data analysis. This paper compares the output signal characteristics from different pressure transducer mounting options, where the passage distance from the transducer face to the pyrotechnic chamber is varied in length and diameter. By analyzing the data and understating the associated system dynamics, a more realistic understanding of the actual dynamic pressure variations is achieved. Three pressure transducer mounting configurations (elongated, standard, and face/flush mount) were simultaneously tested using NASA standard initiators in closed volume pressure bombs. This paper also presents results of these pressure transducer mounting configurations as a result of a larger NASA Engineering and Safety Center pyrovalve test project. Results from these tests indicate the improved performance of using face/flush mounted pressure transducers in this application. This type of mounting improved initial pressure measurement response time by approximately 19 s over standard adapter mounting, eliminating most of the lag time; provided a near step-function type initial pressure increase; and greatly reduced data ringing in high data acquisition rate systems. The paper goes on to discuss other issues associated with the firing and instrumentation that are important for the tester to understand.

  6. Multi Resonance Shear Mode Transducers

    Science.gov (United States)

    2016-11-21

    burden for this collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing...ABSTRACT Crystallographic engineering of single crystal relaxor-based ferroelectrics was used to design broadband, compact, high power, low frequency...using multiple d36 crystal geometries or combinations of d36 and other crystal cuts. 15. SUBJECT TERMS 16. SECURITY CLASSIFICATION OF: 17

  7. The simulation model of planar electrochemical transducer

    Science.gov (United States)

    Zhevnenko, D. A.; Vergeles, S. S.; Krishtop, T. V.; Tereshonok, D. V.; Gornev, E. S.; Krishtop, V. G.

    2016-12-01

    Planar electrochemical systems are very perspective to build modern motion and pressure sensors. Planar microelectronic technology is successfully used for electrochemical transducer of motion parameters. These systems are characterized by an exceptionally high sensitivity towards mechanic exposure due to high rate of conversion of the mechanic signal to electric current. In this work, we have developed a mathematical model of this planar electrochemical system, which detects the mechanical signals. We simulate the processes of mass and charge transfer in planar electrochemical transducer and calculated its transfer function with different geometrical parameters of the system.

  8. Applications of the Method for Transducer Transient Suppression to Various Transducer Types

    Science.gov (United States)

    1993-08-01

    previously. These types are (i) flexural disk, (ii) Helmholtz resonator, (iii) moving coil, (iv) inductor-tuned Tonpilz , and (v)a dual transducer array of...previously. These types are (i) flexural disk. (ii) Helmholtz resonator, (iii) moving coil, (iv) inductor-tuned Tonpilz , and (v) a dual transducer array of...cycle case, we findV(O -- t-- +i, R (t;>r. even number of half-cycles), (3) FIG. 2. Equivalent circuit for an inductor-tuned Tonpilz transducer . The

  9. Transducer-based evaluation of tremor.

    Science.gov (United States)

    Haubenberger, Dietrich; Abbruzzese, Giovanni; Bain, Peter G; Bajaj, Nin; Benito-León, Julián; Bhatia, Kailash P; Deuschl, Günther; Forjaz, Maria João; Hallett, Mark; Louis, Elan D; Lyons, Kelly E; Mestre, Tiago A; Raethjen, Jan; Stamelou, Maria; Tan, Eng-King; Testa, Claudia M; Elble, Rodger J

    2016-09-01

    The International Parkinson and Movement Disorder Society established a task force on tremor that reviewed the use of transducer-based measures in the quantification and characterization of tremor. Studies of accelerometry, electromyography, activity monitoring, gyroscopy, digitizing tablet-based measures, vocal acoustic analysis, and several other transducer-based methods were identified by searching PubMed.gov. The availability, use, acceptability, reliability, validity, and responsiveness were reviewed for each measure using the following criteria: (1) used in the assessment of tremor; (2) used in published studies by people other than the developers; and (3) adequate clinimetric testing. Accelerometry, gyroscopy, electromyography, and digitizing tablet-based measures fulfilled all three criteria. Compared to rating scales, transducers are far more sensitive to changes in tremor amplitude and frequency, but they do not appear to be more capable of detecting a change that exceeds random variability in tremor amplitude (minimum detectable change). The use of transducer-based measures requires careful attention to their limitations and validity in a particular clinical or research setting. © 2016 International Parkinson and Movement Disorder Society.

  10. Broadband, High-Temperature Ultrasonic Transducer

    Science.gov (United States)

    Parker, F. Raymond; Winfree, William P.; Barrows, Danny A.

    1995-01-01

    Materials chosen for endurance at high temperatures and acoustic coupling and damping. Acoustic transducer designed to exhibit broad frequency response and to survive temperatures close to melting points of brazing alloys. Attached directly and continuously to hot object monitored ultrasonically: for example, it can be attached to relatively cool spot on workpiece during brazing for taking ultrasonic quality-control measurements.

  11. Pressure compensated transducer system with constrained diaphragm

    Science.gov (United States)

    Percy, Joseph L.

    1992-08-01

    An acoustic source apparatus has an acoustic transducer that is enclosed in a substantially rigid and watertight enclosure to resist the pressure of water on the transducer and to seal the transducer from the water. The enclosure has an opening through which acoustic signals pass and over which is placed a resilient, expandable and substantially water-impermeable diaphragm. A net stiffens and strengthens the diaphragm as well as constrains the diaphragm from overexpansion or from migrating due to buoyancy forces. Pressurized gas, regulated at slightly above ambient pressure, is supplied to the enclosure and the diaphragm to compensate for underwater ambient pressures. Gas pressure regulated at above ambient pressure is used to selectively tune the pressure levels within the enclosure and diaphragm so that diaphragm resonance can be achieved. Controls are used to selectively fill, as well as vent the enclosure and diaphragm during system descent and ascent, respectively. A signal link is used to activate these controls and to provide the driving force for the acoustic transducer.

  12. An IVUS Transducer for Microbubble Therapies

    Science.gov (United States)

    Kilroy, Joseph P.; Patil, Abhay V.; Rychak, Joshua J.; Hossack, John A.

    2014-01-01

    There is interest in examining the potential of modified intravascular ultrasound (IVUS) catheters to facilitate dual diagnostic and therapeutic roles using ultrasound plus microbubbles for localized drug delivery to the vessel wall. The goal of this study was to design, prototype, and validate an IVUS transducer for microbubble-based drug delivery. A 1-D acoustic radiation force model and finite element analysis guided the design of a 1.5-MHz IVUS transducer. Using the IVUS transducer, biotinylated microbubbles were displaced in water and bovine whole blood to the streptavidin-coated wall of a flow phantom by a 1.5-MHz center frequency, peak negative pressure = 70 kPa pulse with varying pulse repetition frequency (PRF) while monitoring microbubble adhesion with ultrasound. A fit was applied to the RF data to extract a time constant (τ). As PRF was increased in water, the time constant decreased (τ = 32.6 s, 1 kHz vs. τ = 8.2 s, 6 kHz), whereas in bovine whole blood an adhesion–no adhesion transition was found for PRFs ≥ 8 kHz. Finally, a fluorophore was delivered to an ex vivo swine artery using microbubbles and the IVUS transducer, resulting in a 6.6-fold increase in fluorescence. These results indicate the importance of PRF (or duty factor) for IVUS acoustic radiation force microbubble displacement and the potential for IVUS and microbubbles to provide localized drug delivery. PMID:24569249

  13. Eliminating transducer distortion in acoustic measurements

    DEFF Research Database (Denmark)

    Agerkvist, Finn T.; Torras Rosell, Antoni; McWalter, Richard Ian

    2014-01-01

    This paper investigates the in uence of nonlinear components that contaminate the linear response of acoustic transducer, and presents a method for eliminating the in uence of nonlinearities in acoustic measurements. The method is evaluated on simulated as well as experimental data, and is shown...

  14. Pushdown machines for the macro tree transducer

    NARCIS (Netherlands)

    Engelfriet, Joost; Vogler, Heiko

    1986-01-01

    The macro tree transducer can be considered as a system of recursive function procedures with parameters, where the recursion is on a tree (e.g., the syntax tree of a program). We investigate characterizations of the class of tree (tree-to-string) translations which is induced by macro tree

  15. Analysis of multifrequency langevin composite ultrasonic transducers.

    Science.gov (United States)

    Lin, Shuyu

    2009-09-01

    The multimode coupled vibration of Langevin composite ultrasonic transducers with conical metal mass of large cross-section is analyzed. The coupled resonance and anti-resonance frequency equations are derived and the effective electromechanical coupling coefficient is analyzed. The effect of the geometrical dimensions on the resonance frequency, the anti-resonance frequency, and the effective electromechanical coupling coefficient is studied. It is illustrated that when the radial dimension is large compared with the longitudinal dimension, the vibration of the Langevin transducer becomes a multifrequency multimode coupled vibration. Numerical methods are used to simulate the coupled vibration; the simulated results are in good agreement with those from the analytical results. Some Langevin transducers of large cross-section are designed and manufactured and their resonance frequencies are measured. It can be seen that the resonance frequencies obtained from the coupled resonance frequency equations are in good agreement with the measured results. It is expected that by properly choosing the dimensions, multifrequency Langevin transducers can be designed and used in ultrasonic cleaning, ultrasonic sonochemistry, and other applications.

  16. Numerical modeling of piezoelectric transducers using physical parameters.

    Science.gov (United States)

    Cappon, Hans; Keesman, Karel J

    2012-05-01

    Design of ultrasonic equipment is frequently facilitated with numerical models. These numerical models, however, need a calibration step, because usually not all characteristics of the materials used are known. Characterization of material properties combined with numerical simulations and experimental data can be used to acquire valid estimates of the material parameters. In our design application, a finite element (FE) model of an ultrasonic particle separator, driven by an ultrasonic transducer in thickness mode, is required. A limited set of material parameters for the piezoelectric transducer were obtained from the manufacturer, thus preserving prior physical knowledge to a large extent. The remaining unknown parameters were estimated from impedance analysis with a simple experimental setup combined with a numerical optimization routine using 2-D and 3-D FE models. Thus, a full set of physically interpretable material parameters was obtained for our specific purpose. The approach provides adequate accuracy of the estimates of the material parameters, near 1%. These parameter estimates will subsequently be applied in future design simulations, without the need to go through an entire series of characterization experiments. Finally, a sensitivity study showed that small variations of 1% in the main parameters caused changes near 1% in the eigenfrequency, but changes up to 7% in the admittance peak, thus influencing the efficiency of the system. Temperature will already cause these small variations in response; thus, a frequency control unit is required when actually manufacturing an efficient ultrasonic separation system.

  17. Piezoelectric micromachined ultrasound transducer (PMUT) arrays for integrated sensing, actuation and imaging

    National Research Council Canada - National Science Library

    Qiu, Yongqiang; Gigliotti, James V; Wallace, Margeaux; Griggio, Flavio; Demore, Christine E M; Cochran, Sandy; Trolier-McKinstry, Susan

    2015-01-01

    .... Piezoelectric micromachined ultrasound transducers (PMUTs), diaphragm-like thin film flexural transducers typically formed on silicon substrates, are a potential solution for integrated transducer arrays...

  18. Advanced piezoelectric single crystal based transducers for naval sonar applications

    Science.gov (United States)

    Snook, Kevin A.; Rehrig, Paul W.; Hackenberger, Wesley S.; Jiang, Xiaoning; Meyer, Richard J., Jr.; Markley, Douglas

    2006-03-01

    Transducers incorporating single crystal piezoelectric Pb(Mg 1/3Nb 2/3) x-1Ti xO 3 (PMN-PT) exhibit significant advantages over ceramic piezoelectrics such as PZT, including both high electromechanical coupling (k 33 > 90%) and piezoelectric coefficients (d 33 > 2000 pC/N). Conventional orientation gives inherently larger bandwidth and output power than PZT ceramics, however, the anisotropy of the crystal also allows for tailoring of the performance by orienting the crystal along different crystallographic axes. This attribute combined with composition refinements can be used to improve thermal or mechanical stability, which is important in high power, high duty cycle sonar applications. By utilizing the "31" resonance mode, the high power performance of PMN-PT can be improved over traditional "33" mode single crystal transducers, due to an improved aspect ratio. Utilizing novel geometries, effective piezoelectric constants of -600 pC/N to -1200 pC/N have been measured. The phase transition point induced by temperature, pre-stress or field is close to that in the "33" mode, and since the prestress is applied perpendicular to the poling direction in "31" mode elements, they exhibit lower loss and can therefore be driven harder. The high power characteristics of tonpilz transducers can also be affected by the composition of the PMN-PT crystal. TRS modified the composition of PMN-PT to improve the thermal stability of the material, while keeping the loss as low as possible. Three dimensional modeling shows that the useable bandwidth of these novel compositions nearly equals that of conventional PMN-PT. A decrease in the source level of up to 6 dB was calculated, which can be compensated for by the higher drive voltages possible.

  19. Photoacoustic tomography of monkey brain using virtual point ultrasonic transducers

    OpenAIRE

    Nie, Liming; Guo, Zijian; Wang, Lihong V.

    2011-01-01

    A photoacoustic tomography system (PAT) using virtual point ultrasonic transducers was developed and applied to image a monkey brain. The custom-built transducers provide a 10-fold greater field-of-view (FOV) than finite-aperture unfocused transducers as well as an improved signal-to-noise ratio (SNR) and reduced artifacts rather than negative-lens transducers. Their tangential resolution, radial resolution, and (SNR) improvements were quantified using tissue phantoms. Our PAT system can achi...

  20. The effect of electronically steering a phased array ultrasound transducer on near-field tissue heating

    Science.gov (United States)

    Payne, Allison; Vyas, Urvi; Todd, Nick; Bever, Joshua de; Christensen, Douglas A.; Parker, Dennis L.

    2011-01-01

    Purpose: This study presents the results obtained from both simulation and experimental techniques that show the effect of mechanically or electronically steering a phased array transducer on proximal tissue heating. Methods: The thermal response of a nine-position raster and a 16-mm diameter circle scanning trajectory executed through both electronic and mechanical scanning was evaluated in computer simulations and experimentally in a homogeneous tissue-mimicking phantom. Simulations were performed using power deposition maps obtained from the hybrid angular spectrum (HAS) method and applying a finite-difference approximation of the Pennes’ bioheat transfer equation for the experimentally used transducer and also for a fully sampled transducer to demonstrate the effect of acoustic window, ultrasound beam overlap and grating lobe clutter on near-field heating. Results: Both simulation and experimental results show that electronically steering the ultrasound beam for the two trajectories using the 256-element phased array significantly increases the thermal dose deposited in the near-field tissues when compared with the same treatment executed through mechanical steering only. In addition, the individual contributions of both beam overlap and grating lobe clutter to the near-field thermal effects were determined through comparing the simulated ultrasound beam patterns and resulting temperature fields from mechanically and electronically steered trajectories using the 256-randomized element phased array transducer to an electronically steered trajectory using a fully sampled transducer with 40 401 phase-adjusted sample points. Conclusions: Three distinctly different three distinctly different transducers were simulated to analyze the tradeoffs of selected transducer design parameters on near-field heating. Careful consideration of design tradeoffs and accurate patient treatment planning combined with thorough monitoring of the near-field tissue temperature will

  1. The effect of electronically steering a phased array ultrasound transducer on near-field tissue heating.

    Science.gov (United States)

    Payne, Allison; Vyas, Urvi; Todd, Nick; de Bever, Joshua; Christensen, Douglas A; Parker, Dennis L

    2011-09-01

    This study presents the results obtained from both simulation and experimental techniques that show the effect of mechanically or electronically steering a phased array transducer on proximal tissue heating. The thermal response of a nine-position raster and a 16-mm diameter circle scanning trajectory executed through both electronic and mechanical scanning was evaluated in computer simulations and experimentally in a homogeneous tissue-mimicking phantom. Simulations were performed using power deposition maps obtained from the hybrid angular spectrum (HAS) method and applying a finite-difference approximation of the Pennes' bioheat transfer equation for the experimentally used transducer and also for a fully sampled transducer to demonstrate the effect of acoustic window, ultrasound beam overlap and grating lobe clutter on near-field heating. Both simulation and experimental results show that electronically steering the ultrasound beam for the two trajectories using the 256-element phased array significantly increases the thermal dose deposited in the near-field tissues when compared with the same treatment executed through mechanical steering only. In addition, the individual contributions of both beam overlap and grating lobe clutter to the near-field thermal effects were determined through comparing the simulated ultrasound beam patterns and resulting temperature fields from mechanically and electronically steered trajectories using the 256-randomized element phased array transducer to an electronically steered trajectory using a fully sampled transducer with 40 401 phase-adjusted sample points. Three distinctly different three distinctly different transducers were simulated to analyze the tradeoffs of selected transducer design parameters on near-field heating. Careful consideration of design tradeoffs and accurate patient treatment planning combined with thorough monitoring of the near-field tissue temperature will help to ensure patient safety during an MRg

  2. An ultrasonic--EMG transducer for biodynamic research.

    Science.gov (United States)

    Watkin, K L; Minifie, F D; Kennedy, J G

    1978-03-01

    This note describes a newly developed single-element muscle action potential/motion transducer. The transcuer was specially designed for speech research. Techniques for use of the transducer are described. Sample data are presented illustrating the capability of the transducer, and applications of the device are discussed.

  3. 21 CFR 890.1615 - Miniature pressure transducer.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Miniature pressure transducer. 890.1615 Section 890.1615 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... Miniature pressure transducer. (a) Identification. A miniature pressure transducer is a device intended for...

  4. 21 CFR 868.2900 - Gas pressure transducer.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Gas pressure transducer. 868.2900 Section 868.2900...) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Monitoring Devices § 868.2900 Gas pressure transducer. (a) Identification. A gas pressure transducer is a device intended for medical purposes that is used to convert gas...

  5. 21 CFR 868.2885 - Gas flow transducer.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Gas flow transducer. 868.2885 Section 868.2885...) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Monitoring Devices § 868.2885 Gas flow transducer. (a) Identification. A gas flow transducer is a device intended for medical purposes that is used to convert gas flow...

  6. 21 CFR 870.2870 - Catheter tip pressure transducer.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Catheter tip pressure transducer. 870.2870 Section 870.2870 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... pressure transducer. (a) Identification. A catheter tip pressure transducer is a device incorporated into...

  7. 21 CFR 870.2840 - Apex cardiographic transducer.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Apex cardiographic transducer. 870.2840 Section 870.2840 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... cardiographic transducer. (a) Identification. An apex cardiographic transducer is a device used to detect motion...

  8. 21 CFR 868.2875 - Differential pressure transducer.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Differential pressure transducer. 868.2875 Section 868.2875 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... transducer. (a) Identification. A differential pressure transducer is a two-chambered device intended for...

  9. Optomechanical transducers for quantum information processing

    CERN Document Server

    Stannigel, K; Sørensen, A S; Lukin, M D; Zoller, P

    2011-01-01

    We discuss the implementation of optical quantum networks where the interface between stationary and photonic qubits is realized by optomechanical transducers [K. Stannigel et al., PRL 105, 220501 (2010)]. This approach does not rely on the optical properties of the qubit and thereby enables optical quantum communication applications for a wide range of solid-state spin- and charge-based systems. We present an effective description of such networks for many qubits and give a derivation of a state transfer protocol for long-distance quantum communication. We also describe how to mediate local on-chip interactions by means of the optomechanical transducers that can be used for entangling gates. We finally discuss experimental systems for the realization of our proposal.

  10. Electromechanical transducer for acoustic telemetry system

    Energy Technology Data Exchange (ETDEWEB)

    Drumheller, Douglas S. (Cedar Crest, NM)

    1993-01-01

    An improved electromechanical transducer is provided for use in an acoustic telemetry system. The transducer of this invention comprises a stack of ferroelectric ceramic disks interleaved with a plurality of spaced electrodes which are used to electrically pole the ceramic disks. The ceramic stack is housed in a metal tubular drill collar segment. The electrodes are preferably alternatively connected to ground potential and driving potential. This alternating connection of electrodes to ground and driving potential subjects each disk to an equal electric field; and the direction of the field alternates to match the alternating direction of polarization of the ceramic disks. Preferably, a thin metal foil is sandwiched between electrodes to facilitate the electrical connection. Alternatively, a thicker metal spacer plate is selectively used in place of the metal foil in order to promote thermal cooling of the ceramic stack.

  11. Electromechanical transducer for acoustic telemetry system

    Energy Technology Data Exchange (ETDEWEB)

    Drumheller, D.S.

    1993-06-22

    An improved electromechanical transducer is provided for use in an acoustic telemetry system. The transducer of this invention comprises a stack of ferroelectric ceramic disks interleaved with a plurality of spaced electrodes which are used to electrically pole the ceramic disks. The ceramic stack is housed in a metal tubular drill collar segment. The electrodes are preferably alternatively connected to ground potential and driving potential. This alternating connection of electrodes to ground and driving potential subjects each disk to an equal electric field; and the direction of the field alternates to match the alternating direction of polarization of the ceramic disks. Preferably, a thin metal foil is sandwiched between electrodes to facilitate the electrical connection. Alternatively, a thicker metal spacer plate is selectively used in place of the metal foil in order to promote thermal cooling of the ceramic stack.

  12. New piezoelectric transducers for therapeutic ultrasound.

    Science.gov (United States)

    Chapelon, J Y; Cathignol, D; Cain, C; Ebbini, E; Kluiwstra, J U; Sapozhnikov, O A; Fleury, G; Berriet, R; Chupin, L; Guey, J L

    2000-01-01

    Therapeutic ultrasound (US) has been of increasing interest during the past few years. However, the development of this technique depends on the availability of high-performance transducers. These transducers have to be optimised for focusing and steering high-power ultrasonic energy within the target volume. Recently developed high-power 1-3 piezocomposite materials bring to therapeutic US the exceptional electroacoustical properties of piezocomposite technology: these are high efficiency, large bandwidth, predictable beam pattern, more flexibility in terms of shaping and definition of sampling in annular arrays, linear arrays or matrix arrays. The construction and evaluation of several prototypes illustrates the benefit of this new approach that opens the way to further progress in therapeutic US.

  13. Hybrid neural network models of transducers

    Science.gov (United States)

    Xie, Shilin; Zhang, Xinong; Chen, Shenglai; Zhu, Changchun

    2011-10-01

    A hybrid neural network (NN) approach is proposed and applied to modeling of transducers in the paper. The modeling procedures are also presented in detail. First, the simulated studies on the modeling of single input-single output and multi input-multi output transducers are conducted respectively by use of the developed hybrid NN scheme. Secondly, the hybrid NN modeling approach is utilized to characterize a six-axis force sensor prototype based on the measured data. The results show that the hybrid NN approach can significantly improve modeling precision in comparison with the conventional modeling method. In addition, the method is superior to NN black-box modeling because the former possesses smaller network scale, higher convergence speed, higher model precision and better generalization performance.

  14. Orbital angular momentum-entanglement frequency transducer

    CERN Document Server

    Zhou, Zhi-Yuan; Li, Yan; Ding, Dong-Sheng; Zhang, Wei; Shi, Shuai; Dong, Ming-Xin; Shi, Bao-Sen; Guo, Guang-Can

    2016-01-01

    Entanglement is a vital resource for realizing many tasks such as teleportation, secure key distribution, metrology and quantum computations. To effectively build entanglement between different quantum systems and share information between them, a frequency transducer to convert between quantum states of different wavelengths while retaining its quantum features is indispensable. Information encoded in the photons orbital angular momentum OAM degrees of freedom is preferred in harnessing the information carrying capacity of a single photon because of its unlimited dimensions. A quantum transducer, which operates at wavelengths from 1558.3 nm to 525 nm for OAM qubits, OAMpolarization hybrid entangled states, and OAM entangled states, is reported for the first time. Nonclassical properties and entanglements are demonstrated following the conversion process by performing quantum tomography, interference, and Bell inequality measurements. Our results demonstrate the capability to create an entanglement link betwe...

  15. Self-Aligned Interdigitated Transducers for Acoustofluidics

    Directory of Open Access Journals (Sweden)

    Zhichao Ma

    2016-11-01

    Full Text Available The surface acoustic wave (SAW is effective for the manipulation of fluids and particles at microscale. The current approach of integrating interdigitated transducers (IDTs for SAW generation into microfluidic channels involves complex and laborious microfabrication steps. These steps often require full access to clean room facilities and hours to align the transducers to the precise location. This work presents an affordable and innovative method for fabricating SAW-based microfluidic devices without the need for clean room facilities and alignment. The IDTs and microfluidic channels are fabricated using the same process and thus are precisely self-aligned in accordance with the device design. With the use of the developed fabrication approach, a few types of different SAW-based microfluidic devices have been fabricated and demonstrated for particle separation and active droplet generation.

  16. Putting encyclopaedia knowledge into structural form: finite state transducers approach.

    Science.gov (United States)

    Pajić, Vesna

    2011-08-18

    In biology and functional genomics in particular, understanding the dependence and interplay between different genome and ecological characteristics of organisms is a very challenging problem. There are some public databases which combine this kind of information, but there is still much more information about microbes and other organisms that reside in unstructured and semi-structured documents, such as encyclopaedias. In this paper we present a method for extracting information from semi-structured resources, such as encyclopaedias, based on finite state transducers, consisting of two clearly distinguished phases. The first phase strongly relies on the analysis of the document structure and it is used for locating records of data in the text. The second phase is based on the finite state transducers created for extracting the data, which can be modified so as to achieve the preferred efficiency and it is used for extracting the particular characteristic from the text. We show how the two phase method is applied to the text of the encyclopaedia "Systematic Bacteriology". A fully structured database with genotype and phenotype characteristics of organisms has been created from the encyclopaedia unstructured descriptions.

  17. Transducer Arrays Suitable for Acoustic Imaging

    Science.gov (United States)

    1978-06-01

    extensional resonance of a thin plate. The stif- fened velocity and acoustic im.pedance of the transducer can be defined then as follows: ,,,D 1/2 󈧥 (3...finite radius performing rotaticnal oscillations about its center. Case (a) is identical to the cne evaluated in this pape-. The integrals in...Poisson’s ratio. For (k.L) > I , the impedance is essen- tially real and oscillates slowly about the longitudinal plane wave impedance. Below (k,L) = 1

  18. Updated Results of Ultrasonic Transducer Irradiation Test

    Energy Technology Data Exchange (ETDEWEB)

    Daw, Joshua; Palmer, Joe [Idaho National Laboratory, P.O. Box 1625, MS 4112, Idaho Falls, ID, 38415-3840 (United States); Ramuhalli, Pradeep; Keller, Paul; Montgomery, Robert [Pacific Northwest National Laboratory, 902 Battelle Blvd. Richland, WA, 99354 (United States); Chien, Hual-Te [Argonne National Laboratory, 9700 S. Cass Avenue Argonne, IL, 60439 (United States); Tittmann, Bernhard; Reinhardt, Brian [Pennsylvania State University, 212 Earth and Engr. Sciences Building, University Park, PA, 16802 (United States); Kohse, Gordon [Massachusetts Institute of Technology, 77 Massachusetts Ave. Cambridge, MA 02139 (United States); Rempe, Joy [Rempe and Associates, LLC, 360 Stillwater, Idaho Falls, ID 83404 (United States); Villard, J.F. [Commissariat a l' energie atomique et aux energies alternatives, Centre d' etudes de Cadarache, 13108 Saint-Paul-lez-Durance (France)

    2015-07-01

    Ultrasonic technologies offer the potential for high accuracy and resolution in-pile measurement of a range of parameters, including geometry changes, temperature, crack initiation and growth, gas pressure and composition, and microstructural changes. Many Department of Energy-Office of Nuclear Energy (DOE-NE) programs are exploring the use of ultrasonic technologies to provide enhanced sensors for in-pile instrumentation during irradiation testing. For example, the ability of small diameter ultrasonic thermometers (UTs) to provide a temperature profile in candidate metallic and oxide fuel would provide much needed data for validating new fuel performance models. These efforts are limited by the lack of identified ultrasonic transducer materials capable of long term performance under irradiation test conditions. To address this need, the Pennsylvania State University (PSU) was awarded an Advanced Test Reactor National Scientific User Facility (ATR NSUF) project to evaluate the performance of promising magnetostrictive and piezoelectric transducers in the Massachusetts Institute of Technology Research Reactor (MITR) up to a fast fluence of at least 10{sup 21} n/cm{sup 2}. A multi-National Laboratory collaboration funded by the Nuclear Energy Enabling Technologies Advanced Sensors and Instrumentation (NEET-ASI) program also provided initial support for this effort. This irradiation, which started in February 2014, is an instrumented lead test and real-time transducer performance data are collected along with temperature and neutron and gamma flux data. The irradiation is ongoing and will continue to approximately mid-2015. To date, very encouraging results have been attained as several transducers continue to operate under irradiation. (authors)

  19. Transducer Analysis and ATILA++ Model Development

    Science.gov (United States)

    2016-10-10

    the ATILA finite element software package. This will greatly enhance the state-of-the-art in transducer performance prediction and provide a tool...The free dielectric constants for soft crystals show significant change with preload which affects device impedance and amplifier considerations...under Static Preload An apparatus and software control system have been fabricated and developed for evaluating the behavior of materials under high

  20. Characterization of transducer cavities to oscillatory inputs

    Energy Technology Data Exchange (ETDEWEB)

    Rogers, J.D.; Hollingshead, J.R.

    1993-12-31

    The design and use of measurement systems must ensure that the data are not computed by the measurement system. A wide variety of sources can be responsible for compromising the integrity of test data. Among the sources of error are transducer calibration errors, signal conditioning problems, recording problems, and characteristics of the mechanical system which introduce errors. In this paper, the characteristics of an acoustic cavity are discussed as they apply to a pressure measurement problem.

  1. Micromachined capacitive transducer arrays for intravascular ultrasound

    Science.gov (United States)

    Degertekin, F. Levent; Guldiken, R. Oytun; Karaman, Mustafa

    2005-01-01

    Intravascular ultrasound (IVUS) imaging has become an essential imaging modality for the effective diagnosis and treatment of cardiovascular diseases during the past decade enabled by innovative applications of piezoelectric transducer technology. The limitations in the manufacture and performance of the same piezoelectric transducers have also impeded the improvement of IVUS for emerging clinically important applications such as forward viewing arrays for guiding interventions and high resolution imaging of arterial structure such as vulnerable plaque and fibrous cap, and also implementation of techniques such as harmonic imaging of the tissue and of the contrast agents. Capacitive micromachined ultrasonic transducer (CMUT) technology shows great potential for transforming IVUS not only to satisfy these clinical needs but also to open up possibilities for low-cost imaging devices integrated to therapeutic tools. We have developed manufacturing processes with a maximum process temperature of 250°C to build CMUTs on the same silicon chip with integrated electronics. Using these processes we fabricated CMUT arrays suitable for forward viewing IVUS in the 10-20MHz range. We characterized these array elements in terms of pulse-echo response, radiation pattern measurements and demonstrated its volumetric imaging capabilities on various imaging targets.

  2. Cross-fiber Bragg grating transducer

    Science.gov (United States)

    Albin, Sacharia (Inventor); Zheng, Jianli (Inventor); Lavarias, Arnel (Inventor)

    2000-01-01

    A transducer has been invented that uses specially-oriented gratings in waveguide a manner that allows the simultaneous measurement of physical phenomena (such as shear force, strain and temperature) in a single sensing element. The invention has a highly sensitive, linear response and also has directional sensitivity with regard to strain. The transducer has a waveguide with a longitudinal axis as well as two Bragg gratings. The transducer has a first Bragg grating associated with the waveguide that has an angular orientation .theta..sub.a relative to a perpendicular to the longitudinal axis such that 0.degree.<.theta..sub.a <.theta..sub.max. The second Bragg grating is associated with the waveguide in such a way that the angular orientation .theta..sub.b of the grating relative to a perpendicular to the longitudinal axis is (360.degree.-.theta..sub.max)<.theta..sub.b <360.degree.. The first Bragg grating can have a periodicity .LAMBDA..sub.a and the second Bragg grating can have a periodicity .LAMBDA..sub.b such that the periodicity .LAMBDA..sub.a of the first Bragg grating does not equal the periodicity .LAMBDA..sub.b of the second Bragg grating. The angle of the gratings can be such that .theta..sub.a =360.degree.-.theta..sub.b. The waveguide can assume a variety of configurations, including an optical fiber, a rectangular waveguide and a planar waveguide. The waveguide can be fabricated of a variety of materials, including silica and polymer material.

  3. A Neoprene with Optimized Bondability for Sonar Transducer Applications

    Science.gov (United States)

    1987-06-05

    TR-317R TRANSDUCER The TR-317R is a tonpilz transducer mounted in a large spherical array on the front of U.S. Navy submarines of several classes... TRANSDUCER APPLICATIONS TASK NO. 59-0593-0 [SQ-ns«A-n WORK UNIT ACCESSION NO. )N880-326 12. PERSONAL AUTHOR(S) "^ ^Zl!l ^’ ’^’^°"’P"°" ^"i... Transducer Applications tX: C. M. Thompson Materials Section Transducer Branch Underwater Sound Reference Detachment Naval Research Laboratory P.O

  4. Language of Transducer Manipulation: Codifying Terms for Effective Teaching.

    Science.gov (United States)

    Bahner, David P; Blickendorf, J Matthew; Bockbrader, Marcia; Adkins, Eric; Vira, Amar; Boulger, Creagh; Panchal, Ashish R

    2016-01-01

    There is a need for consistent, repetitive, and reliable terminology to describe the basic manipulations of the ultrasound transducer. Previously, 5 basic transducer motions have been defined and used in education. However, even with this effort, there is still a lack of consistency and clarity in describing transducer manipulation and motion. In this technical innovation, we describe an expanded definition of transducer motions, which include movements to change the transducer's angle of insonation to the target as well as the location on the body to optimize the ultrasound image. This new terminology may allow for consistent teaching and improved communication in the process of image acquisition.

  5. Observation of skull-guided acoustic waves in a water-immersed murine skull using optoacoustic excitation

    Science.gov (United States)

    Estrada, Héctor; Rebling, Johannes; Razansky, Daniel

    2017-02-01

    The skull bone, a curved solid multilayered plate protecting the brain, constitutes a big challenge for the use of ultrasound-mediated techniques in neuroscience. Ultrasound waves incident from water or soft biological tissue are mostly reflected when impinging on the skull. To this end, skull properties have been characterized for both high-intensity focused ultrasound (HIFU) operating in the narrowband far-field regime and optoacoustic imaging applications. Yet, no study has been conducted to characterize the near-field of water immersed skulls. We used the thermoelastic effect with a 532 nm pulsed laser to trigger a wide range of broad-band ultrasound modes in a mouse skull. In order to capture the waves propagating in the near-field, a thin hydrophone was scanned in close proximity to the skull's surface. While Leaky pseudo-Lamb waves and grazing-angle bulk water waves are clearly visible in the spatio-temporal data, we were only able to identify skull-guided acoustic waves after dispersion analysis in the wavenumber-frequency space. The experimental data was found to be in a reasonable agreement with a flat multilayered plate model.

  6. Steerable vertical to horizontal energy transducer for mobile robots

    Science.gov (United States)

    Spletzer, Barry L.; Fischer, Gary J.; Feddema, John T.

    2001-01-01

    The present invention provides a steerable vertical to horizontal energy transducer for mobile robots that less complex and requires less power than two degree of freedom tilt mechanisms. The present invention comprises an end effector that, when mounted with a hopping actuator, translates along axis (typically vertical) actuation into combined vertical and horizontal motion. The end effector, or foot, mounts with an end of the actuator that moves toward the support surface (typically a floor or the earth). The foot is shaped so that the first contact with the support surface is off the axis of the actuator. Off-axis contact with the support surface generates an on-axis force (typically resulting in vertical motion) and a moment orthogonal to the axis. The moment initiates a horizontal tumbling motion, and tilts the actuator so that its axis is oriented with a horizontal component and continued actuation generates both vertical and horizontal force.

  7. Front-end receiver electronics for a matrix transducer for 3-D transesophageal echocardiography.

    Science.gov (United States)

    Yu, Zili; Blaak, Sandra; Chang, Zu-yao; Yao, Jiajian; Bosch, Johan G; Prins, Christian; Lancée, Charles T; de Jong, Nico; Pertijs, Michiel A P; Meijer, Gerard C M

    2012-07-01

    There is a clear clinical need for creating 3-D images of the heart. One promising technique is the use of transesophageal echocardiography (TEE). To enable 3-D TEE, we are developing a miniature ultrasound probe containing a matrix piezoelectric transducer with more than 2000 elements. Because a gastroscopic tube cannot accommodate the cables needed to connect all transducer elements directly to an imaging system, a major challenge is to locally reduce the number of channels, while maintaining a sufficient signal-to-noise ratio. This can be achieved by using front-end receiver electronics bonded to the transducers to provide appropriate signal conditioning in the tip of the probe. This paper presents the design of such electronics, realizing time-gain compensation (TGC) and micro-beamforming using simple, low-power circuits. Prototypes of TGC amplifiers and micro-beamforming cells have been fabricated in 0.35-μm CMOS technology. These prototype chips have been combined on a printed circuit board (PCB) to form an ultrasound-receiver system capable of reading and combining the signals of three transducer elements. Experimental results show that this design is a suitable candidate for 3-D TEE.

  8. Ultrasound transducer function: annual testing is not sufficient.

    Science.gov (United States)

    Mårtensson, Mattias; Olsson, Mats; Brodin, Lars-Åke

    2010-10-01

    The objective was to follow-up the study 'High incidence of defective ultrasound transducers in use in routine clinical practice' and evaluate if annual testing is good enough to reduce the incidence of defective ultrasound transducers in routine clinical practice to an acceptable level. A total of 299 transducers were tested in 13 clinics at five hospitals in the Stockholm area. Approximately 7000-15,000 ultrasound examinations are carried out at these clinics every year. The transducers tested in the study had been tested and classified as fully operational 1 year before and since then been in normal use in the routine clinical practice. The transducers were tested with the Sonora FirstCall Test System. There were 81 (27.1%) defective transducers found; giving a 95% confidence interval ranging from 22.1 to 32.1%. The most common transducer errors were 'delamination' of the ultrasound lens and 'break in the cable' which together constituted 82.7% of all transducer errors found. The highest error rate was found at the radiological clinics with a mean error rate of 36.0%. There was a significant difference in error rate between two observed ways the clinics handled the transducers. There was no significant difference in the error rates of the transducer brands or the transducers models. Annual testing is not sufficient to reduce the incidence of defective ultrasound transducers in routine clinical practice to an acceptable level and it is strongly advisable to create a user routine that minimizes the handling of the transducers.

  9. Safety Issues for HIFU Transducer Design

    Science.gov (United States)

    Fleury, Gérard; Berriet, Rémi; Chapelon, Jean Yves; ter Haar, Gail; Lafon, Cyril; Le Baron, Olivier; Chupin, Laurent; Pichonnat, Fabrice; Lenormand, Jérôme

    2005-03-01

    In contrast with most ultrasound modalities for medical applications, (especially ultrasound imaging), High Intensity Focused Ultrasound (HIFU) involves technologies and procedures which may present risk to the patient. These risks, resulting from the high power levels required for effective therapy, should be taken into account at the earliest stages in the design of a system dedicated to HIFU treatment. An understanding of these risks must thus be shared amongst the many players in the field of therapy using high power ultrasound. Moreover, since the number of applications of HIFU has increased appreciably over recent years and the technology is ready to move from the research to the industrial level, it is worth now considering solutions that should be put in place to guarantee the safety of the patient during HIFU treatment. This paper reports thoughts on this, identifies some risks to the patient that must be taken into consideration in the design of HIFU transducers, and proposes some solutions that could prevent the deleterious consequences of transducer misuse or failure. For the main risks identified, such as exceeding the desired acoustic power or poor control of tissue targeting, a description of transducer performance that could potentially result in problems is systematically sought. This allows proposals for precautions to be taken during operation to be made. Parameters which should be monitored to ensure safe use are also suggested. This type of approach, which should be undertaken for the different components of a therapeutic system, highlights the challenges that must be faced in the immediate future for the development and safe exploitation of HIFU systems. The necessity for standard definitions of the parameters to be checked or monitored during HIFU treatments is crucial in this approach, as is the availability of reliable dedicated measurement devices. Co-ordinated action on these topics in the HIFU community would contribute to the

  10. Dynamics of receptor and protein transducer homodimerisation

    Directory of Open Access Journals (Sweden)

    Kolch Walter

    2008-10-01

    Full Text Available Abstract Background Signalling pathways are complex systems in which not only simple monomeric molecules interact, but also more complex structures that include constitutive or induced protein assemblies. In particular, the hetero-and homo-dimerisation of proteins is a commonly encountered motif in signalling pathways. Several authors have suggested in recent times that dimerisation relates to a series of physical and biological outcomes used by the cell in the regulation of signal transduction. Results In this paper we investigate the role of homodimerisation in receptor-protein transducer interactions. Towards this end, mathematical modelling is used to analyse the features of such kind of interactions and to predict the behaviour of the system under different experimental conditions. A kinetic model in which the interaction between homodimers provokes a dual mechanism of activation (single and double protein transducer activation at the same time is proposed. In addition, we analyse under which conditions the use of a power-law representation for the system is useful. Furthermore, we investigate the dynamical consequences of this dual mechanism and compare the performance of the system in different simulated experimental conditions. Conclusion The analysis of our mathematical model suggests that in receptor-protein interacting systems with dual mechanism there may be a shift between double and single activation in a way that intense double protein transducer activation could initiate and dominate the signal in the short term (getting a fast intense signal, while single protein activation could control the system in the medium and long term (when input signal is weaker and decreases slowly. Our investigation suggests that homodimerisation and oligomerisation are mechanisms used to enhance and regulate the dynamic properties of the initial steps in signalling pathways.

  11. A Hail Size Distribution Impact Transducer

    CERN Document Server

    Lane, John E; Haskell, William D; Cox, Robert B

    2014-01-01

    An active impact transducer has been designed and tested for the purpose of monitoring hail fall in the vicinity of the Space Shuttle launch pads. An important outcome of this design is the opportunity to utilize frequency analysis to discriminate between the audio signal generated from raindrop impacts and that of hailstone impacts. The sound of hail impacting a metal plate is sub-tly but distinctly different than the sound of rain impacts. This useful characteristic permits application of signal processing algorithms that are inherently more robust than techniques relying on amplitude processing alone in the implementation of a hail disdrometer.

  12. Floating Ultrasonic Transducer Inspection System and Method for Nondestructive Evaluation

    Science.gov (United States)

    Zalameda, Joseph N. (Inventor); Johnston, Patrick H. (Inventor)

    2016-01-01

    A method for inspecting a structural sample using ultrasonic energy includes positioning an ultrasonic transducer adjacent to a surface of the sample, and then transmitting ultrasonic energy into the sample. Force pulses are applied to the transducer concurrently with transmission of the ultrasonic energy. A host machine processes ultrasonic return pulses from an ultrasonic pulser/receiver to quantify attenuation of the ultrasonic energy within the sample. The host machine detects a defect in the sample using the quantified level of attenuation. The method may include positioning a dry couplant between an ultrasonic transducer and the surface. A system includes an actuator, an ultrasonic transducer, a dry couplant between the transducer the sample, a scanning device that moves the actuator and transducer, and a measurement system having a pulsed actuator power supply, an ultrasonic pulser/receiver, and a host machine that executes the above method.

  13. Orbital Angular Momentum-Entanglement Frequency Transducer

    Science.gov (United States)

    Zhou, Zhi-Yuan; Liu, Shi-Long; Li, Yan; Ding, Dong-Sheng; Zhang, Wei; Shi, Shuai; Dong, Ming-Xin; Shi, Bao-Sen; Guo, Guang-Can

    2016-09-01

    Entanglement is a vital resource for realizing many tasks such as teleportation, secure key distribution, metrology, and quantum computations. To effectively build entanglement between different quantum systems and share information between them, a frequency transducer to convert between quantum states of different wavelengths while retaining its quantum features is indispensable. Information encoded in the photon's orbital angular momentum (OAM) degrees of freedom is preferred in harnessing the information-carrying capacity of a single photon because of its unlimited dimensions. A quantum transducer, which operates at wavelengths from 1558.3 to 525 nm for OAM qubits, OAM-polarization hybrid-entangled states, and OAM-entangled states, is reported for the first time. Nonclassical properties and entanglements are demonstrated following the conversion process by performing quantum tomography, interference, and Bell inequality measurements. Our results demonstrate the capability to create an entanglement link between different quantum systems operating in a photon's OAM degrees of freedom, which will be of great importance in building a high-capacity OAM quantum network.

  14. Instantaneous crack detection using dual PZT transducers

    Science.gov (United States)

    Kim, Seung Bum; Sohn, Hoon

    2008-03-01

    A new guided wave based nondestructive testing (NDT) technique is developed to detect crack damage in metallic plates commonly used in aircraft without using prior baseline data or a predetermined decision boundary. In conventional guided wave based techniques, damage is often identified by comparing the "current" data obtained from a potentially damaged condition of a structure with the "past" baseline data collected at the pristine condition of the structure. However, it has been reported that this type of pattern comparison with the baseline data can lead to increased false alarms due to its susceptibility to varying operational and environmental conditions of the structure. In order to tackle this issue, a reference-free damage detection technique is previously developed using two pairs of collocated lead zirconate titanate transducers (PZTs) placed on both sides of a plate. In this study, this reference-free technique is further advanced so that the PZT transducers can be placed only on one side of the specimen. Crack formation creates Lamb wave mode conversion due to a sudden change in the thickness of the structure. Then, the proposed technique instantly detects the appearance of the crack by extracting this mode conversion from the measured Lamb waves. This study suggests a reference-free statistical approach that enables damage classification using only the current data set. Numerical and experimental results are presented to demonstrate the applicability of the proposed technique to instantaneous crack detection.

  15. Piezoelectric single crystals for ultrasonic transducers in biomedical applications

    OpenAIRE

    Zhou, Qifa; Lam, Kwok Ho; Zheng, Hairong; Qiu, Weibao; Shung, K. Kirk

    2014-01-01

    Piezoelectric single crystals, which have excellent piezoelectric properties, have extensively been employed for various sensors and actuators applications. In this paper, the state–of–art in piezoelectric single crystals for ultrasonic transducer applications is reviewed. Firstly, the basic principles and design considerations of piezoelectric ultrasonic transducers will be addressed. Then, the popular piezoelectric single crystals used for ultrasonic transducer applications, including LiNbO...

  16. Piezoelectric films for high frequency ultrasonic transducers in biomedical applications

    OpenAIRE

    Zhou, Qifa; Lau, Sienting; WU, DAWEI; Shung, K. Kirk

    2011-01-01

    Piezoelectric films have recently attracted considerable attention in the development of various sensor and actuator devices such as nonvolatile memories, tunable microwave circuits and ultrasound transducers. In this paper, an overview of the state of art in piezoelectric films for high frequency transducer applications is presented. Firstly, the basic principles of piezoelectric materials and design considerations for ultrasound transducers will be introduced. Following the review, the curr...

  17. Low-cost ultrasonic lamb-wave transducer

    Science.gov (United States)

    Kammerer, C. C.

    1978-01-01

    Transducer propagates Lamb wave through thin aluminum sheet material. Model includes two elements that measure effects of damping and loading which, in turn, are indirectly equated to bond integrity. Transducer has been used to evaluate bond integrity of aluminum facing adhesively bonded to aluminum facing. Because of versatility, it is now possible to inspect many objects of different configurations that could not be reached with earlier transducers.

  18. Broadband tonpilz underwater acoustic transducers based on multimode optimization

    OpenAIRE

    Yao, Qingshan; Jensen, Leif Bjørnø

    1997-01-01

    Head flapping has often been considered to be deleterious for obtaining a tonpilz transducer with broadband, high power performance. In the present work, broadband, high power tonpilz transducers have been designed using the finite element (FE) method. Optimized vibrational modes including the flapping mode of the head are effectively used to achieve the broadband performance. The behavior of the transducer in its longitudinal piston mode and in its flapping mode is analysed for in-air and in...

  19. An Algorithm for Selecting Transducer Element Array Positions

    Science.gov (United States)

    1988-06-01

    response. A lumped-parameter equivalent circuit of a tonpilz transducer is used to predict element amplitude and phase tolerances for different radiation...lumped-parameter equivalent circuit of a tonpilz transducer is used to predict element amplitude and phase tolerances for different radiation loadings...FIGURES p Figure Page : 2.1 A Tonpilz Type Transducer . . .............. . 6 % 2.2 The Equivalent Circuit .......... .................... 7 2.3 The

  20. Design and Test of Capacitive Micromachined Ultrasonic Transducer

    National Research Council Canada - National Science Library

    Hongliang Wang; Xiangjun Wang; Changde He; Chenyang Xue; Jijun Xiong; Wendong Zhang; Jing Miao; Yuping Li

    2014-01-01

      Currently, most capacitive micromachined ultrasound transducers, adopting surface sacrificial technology encounter various problems such as difficult cavity etch, low controllability of membrane thickness etc...

  1. MEMS acoustic emission transducers designed with high aspect ratio geometry

    Science.gov (United States)

    Saboonchi, H.; Ozevin, D.

    2013-09-01

    In this paper, micro-electro-mechanic systems (MEMS) acoustic emission (AE) transducers are manufactured using an electroplating technique. The transducers use a capacitance change as their transduction principle, and are tuned to the range 50-200 kHz. Through the electroplating technique, a thick metal layer (20 μm nickel + 0.5 μm gold) is used to form a freely moving microstructure layer. The presence of the gold layer reduces the potential corrosion of the nickel layer. A dielectric layer is deposited between the two electrodes, thus preventing the stiction phenomenon. The transducers have a measured quality factor in the range 15-30 at atmospheric pressure and are functional without vacuum packaging. The transducers are characterized using electrical and mechanical tests to identify the capacitance, resonance frequency and damping. Ultrasonic wave generation using a Q-switched laser shows the directivity of the transducer sensitivity. The comparison of the MEMS transducers with similar frequency piezoelectric transducers shows that the MEMS AE transducers have better response characteristics and sensitivity at the resonance frequency and well-defined waveform signatures (rise time and decay time) due to pure resonance behavior in the out-of-plane direction. The transducers are sensitive to a unique wave direction, which can be utilized to increase the accuracy of source localization by selecting the correct wave velocity at the structures.

  2. Radiation endurance of piezoelectric ultrasonic transducers--a review.

    Science.gov (United States)

    Sinclair, A N; Chertov, A M

    2015-03-01

    A literature survey is presented on the radiation endurance of piezoelectric ultrasonic transducer components and complete transducer assemblies, as functions of cumulative gamma dose and neutron fluence. The most extensive data on this topic has been acquired in CANDU electrical generating stations, which use piezoelectric ultrasonic transducers manufactured commercially with minor accommodation for high radiation fields. They have been found to be reliable for cumulative gamma doses of up to approximately 2 MegaGrays; a brief summary is made of the associated accommodations required to the transducer design, and the ultimate expected failure modes. Outside of the CANDU experience, endurance data have been acquired under a diverse spectrum of operating conditions; this can impede a direct comparison of the information from different sources. Much of this data is associated with transducers immersed in liquid metal coolants associated with advanced reactor designs. Significant modifications to conventional designs have led to the availability of custom transducers that can endure well over 100 MegaGrays of cumulative gamma dose. Published data on transducer endurance against neutron fluence are reviewed, but are either insufficient, or were reported with inadequate description of test conditions, to make general conclusions on transducer endurance with high confidence. Several test projects are planned or are already underway by major laboratories and research consortia to augment the store of transducer endurance data with respect to both gamma and neutron radiation.

  3. Monitoring Method for the Electrical Properties of Piezoelectric Transducer

    Institute of Scientific and Technical Information of China (English)

    李文; 朱泽琪

    2012-01-01

    The monitoring of cutting force in a vibration cutting process has a great significance in the popularization of ultrasonic vibration cutting technology. A new monitoring method of which the cutting force of ultrasonic elliptic vibration cutting is monitored using the electrical properties of transducer was proposed by studying on the relationship of cutting force, transducer electric impedance and load. A measurement system was designed for the electrical properties of transducer. The feasibility of cutting force monitoring method based on the electrical properties of piezoelectric transducer was proved by the cutting experiments.

  4. 21 CFR 892.1570 - Diagnostic ultrasonic transducer.

    Science.gov (United States)

    2010-04-01

    ... that converts electrical signals into acoustic signals and acoustic signals into electrical signals and... include transmission media for acoustically coupling the transducer to the body surface, such as...

  5. Method and results of studying conduction measuring transducers

    Energy Technology Data Exchange (ETDEWEB)

    Dunaevskii, I.G.; Korotkov, B.N.; Povkh, I.L.; Cheplyukov, V.G.

    1977-01-01

    The method and results are given for determining the sensitivity of conduction measuring transducers with a local magnetic field. The results were obtained by frequency-dependent gradation on a model pulsation velocity gauge--a thermoanemometer. The effect of measuring a transducer's diameter, inter-electrode distance and nose line forms on its spatial resolution capacity was estimated. Adjustment functions were obtained for these transducers. A concept was formulated for measuring transducers belonging to the same class. 5 references, 5 figures.

  6. Histotripsy Lesion Formation Using an Ultrasound Imaging Probe Enabled by a Low-Frequency Pump Transducer.

    Science.gov (United States)

    Lin, Kuang-Wei; Hall, Timothy L; Xu, Zhen; Cain, Charles A

    2015-08-01

    When histotripsy pulses shorter than 2 cycles are applied, the formation of a dense bubble cloud relies only on the applied peak negative pressure (p-) exceeding the "intrinsic threshold" of the medium (absolute value of 26-30 MPa in most soft tissues). It has been found that a sub-threshold high-frequency probe pulse (3 MHz) can be enabled by a sub-threshold low-frequency pump pulse (500 kHz) where the sum exceeds the intrinsic threshold, thus generating lesion-producing dense bubble clouds ("dual-beam histotripsy"). Here, the feasibility of using an imaging transducer to provide the high-frequency probe pulse in the dual-beam histotripsy approach is investigated. More specifically, an ATL L7-4 imaging transducer (Philips Healthcare, Andover, MA, USA), pulsed by a V-1 Data Acquisition System (Verasonics, Redmond, WA, USA), was used to generate the high-frequency probe pulses. The low-frequency pump pulses were generated by a 20-element 345-kHz array transducer, driven by a custom high-voltage pulser. These dual-beam histotripsy pulses were applied to red blood cell tissue-mimicking phantoms at a pulse repetition frequency of 1 Hz, and optical imaging was used to visualize bubble clouds and lesions generated in the red blood cell phantoms. The results indicated that dense bubble clouds (and resulting lesions) were generated when the p- of the sub-threshold pump and probe pulses combined constructively to exceed the intrinsic threshold. The average size of the smallest reproducible lesions using the imaging probe pulse enabled by the sub-threshold pump pulse was 0.7 × 1.7 mm, whereas that using the supra-threshold pump pulse alone was 1.4 × 3.7 mm. When the imaging transducer was steered laterally, bubble clouds and lesions were steered correspondingly until the combined p- no longer exceeded the intrinsic threshold. These results were also validated with ex vivo porcine liver experiments. Using an imaging transducer for dual-beam histotripsy can have two

  7. The Cavitation With Plate Transducer And Non Cavitation With Knob Transducer By Manihot Utilissima Fermentation The Potential Hydrogen Ph Method

    Directory of Open Access Journals (Sweden)

    Syamsul Arifin

    2015-08-01

    Full Text Available Abstract Manihot M. utilissima fermentation is popular foods and drinks for Indonesia people but it fermented foods 24 hours per day will breed fungi and anaerobic bacteriae so it will make it into acidic foods and alcoholic beverages. Ultrasonic 48 kHz 5 Vpp 1 VDC with functional generator and of the two models of transducers will have two different phenomena on M. utilissima fermentation. Methods Model-1. Radiation ultrasonic transducer plate or Flat of piezoelectric speakers2 were applied with transducers M. utilissima dipped in a test tube. Model-2. Knob or small ball ultrasonic transducer 12 balls were applied with transducers of tin knob which was connected to the copper wire2 and piezoelectricspeakers were dipped into the media M. utilissima in a test tube. After ultrasonic radiation fluid liquid from two models of transducers measured total acid in M. utilissima fermentation liquid by paper indicators of potential Hydrogen pH. The conclusion of this study can predict different phenomena namely the transducer plate of the initial pH value-acid fermentation M. utilissima can change increases the pH-value end of the base which means that the transducer plate has a cavitation phenomenon and media M. utilissima lead to the delicious food but on transducer knob that the initial pH value-acid fermentation M. utilissima will decrease more acid value so that have no phenomenon of cavitation and the media will lead M. utilissima to be alcoholic foods.

  8. Design optimization of embedded ultrasonic transducers for concrete structures assessment.

    Science.gov (United States)

    Dumoulin, Cédric; Deraemaeker, Arnaud

    2017-08-01

    In the last decades, the field of structural health monitoring and damage detection has been intensively explored. Active vibration techniques allow to excite structures at high frequency vibrations which are sensitive to small damage. Piezoelectric PZT transducers are perfect candidates for such testing due to their small size, low cost and large bandwidth. Current ultrasonic systems are based on external piezoelectric transducers which need to be placed on two faces of the concrete specimen. The limited accessibility of in-service structures makes such an arrangement often impractical. An alternative is to embed permanently low-cost transducers inside the structure. Such types of transducers have been applied successfully for the in-situ estimation of the P-wave velocity in fresh concrete, and for crack monitoring. Up to now, the design of such transducers was essentially based on trial and error, or in a few cases, on the limitation of the acoustic impedance mismatch between the PZT and concrete. In the present study, we explore the working principles of embedded piezoelectric transducers which are found to be significantly different from external transducers. One of the major challenges concerning embedded transducers is to produce very low cost transducers. We show that a practical way to achieve this imperative is to consider the radial mode of actuation of bulk PZT elements. This is done by developing a simple finite element model of a piezoelectric transducer embedded in an infinite medium. The model is coupled with a multi-objective genetic algorithm which is used to design specific ultrasonic embedded transducers both for hard and fresh concrete monitoring. The results show the efficiency of the approach and a few designs are proposed which are optimal for hard concrete, fresh concrete, or both, in a given frequency band of interest. Copyright © 2017 Elsevier B.V. All rights reserved.

  9. Magnetoelastic Transducer Materials - a Plateable Possibility

    DEFF Research Database (Denmark)

    Jensen, Jens Dahl; Møller, Per

    2001-01-01

    A short presentation of the magnetostriction theory as well as a series of possible applications for magnetoelastic transducers are given. A review of the present state of development for these materials is discussed with relation to the various ways of manufacture. The paper is concluded...... with the presentation of a method for making magnetoelastic materials by electrochemical deposition (electroless) as tried by the authors in collaboration with the Daimler-Chrysler research centre in Ulm, Germany. First results of this work are both promising and intriguing: Sensitivities of the same order...... as the reference material Terfenol-D were obtained, but reproduction of exact magnetic properties is still critical with the new plating technique....

  10. Linear ultrasonic motor using quadrate plate transducer

    Institute of Scientific and Technical Information of China (English)

    Jiamei JIN; Chunsheng ZHAO

    2009-01-01

    A linear ultrasonic motor using a quadrate plate transducer was developed for precision positioning. This motor consists of two pairs of Pb(Zr, Ti)O3 piezo-electric ceramic elements, which are piezoelectrically excited into the second-bending mode of the motor stator's neutral surface in two orthogonal directions, on which the tops of four projections move along an elliptical trajectory, which in turn drives a contacted slider into linear motion via frictional forces. The coincident frequency of the stator is easily obtained for its coincident characteristic dimen-sion in two orthogonal directions. The performance characteristics achieved by the motor are: 1) a maximum linear speed of more than 60 mm/s; 2) a stroke of more than 150 mm; 3) a driving force of more than 5.0 N; and 4) a response time of about 2 ms.

  11. Multilayer Array Transducer for Nonlinear Ultrasound Imaging

    Science.gov (United States)

    Owen, Neil R.; Kaczkowski, Peter J.; Li, Tong; Gross, Dan; Postlewait, Steven M.; Curra, Francesco P.

    2011-09-01

    The properties of nonlinear acoustic wave propagation are known to be able to improve the resolution of ultrasound imaging, and could be used to dynamically estimate the physical properties of tissue. However, transducers capable of launching a wave that becomes nonlinear through propagation do not typically have the necessary bandwidth to detect the higher harmonics. Here we present the design and characterization of a novel multilayer transducer for high intensity transmit and broadband receive. The transmit layer was made from a narrow-band, high-power piezoceramic (PZT), with nominal frequency of 2.0 MHz, that was diced into an array of 32 elements. Each element was 0.300 mm wide and 6.3 mm in elevation, and with a pitch of 0.400 mm the overall aperture width was 12.7 mm. A quarter-wave matching layer was attached to the PZT substrate to improve transmit efficiency and bandwidth. The overlaid receive layer was made from polyvinylidene fluoride (PVDF) that had gold metalization on one side. A custom two-sided flex circuit routed electrical connections to the PZT elements and patterned the PVDF elements; the PZT and PVDF elements had identical apertures. A low viscosity and electrically nonconductive epoxy was used for all adhesion layers. Characterization of electrical parameters and acoustic output were performed per standard methods, where transmit and receive events were driven by a software-controlled ultrasound engine. Echo data, collected from ex vivo tissue and digitized at 45 MS/s, exhibited frequency content up to the 4th harmonic of the 2 MHz transmit frequency.

  12. Study on Enhancement Effect of Cavitation Caused by HIFU Piezoelectricity Transducer

    Institute of Scientific and Technical Information of China (English)

    Xinnan Fan; Changping Zhu; Shichuan He; Minglei Shan; Jiacai Chen

    2006-01-01

    An orthogonal ultrasonic irradiation system consisting of HIFU with frequency at 1.05 MHz combined with ultrasound with frequency at 28 kHz was applied in this paper. Effect of cavitation was detected by pH-value measurement and conductance measurement. The result shows that the effect of cavitation caused by ultrasound with frequency at 28 kHz is greatly enhanced by HIFU piezoelectricity transducer with frequency at 1.05 MHz.

  13. Thermal dispersion method for an ultrasonic phased-array transducer

    Science.gov (United States)

    Choi, Euna; Lee, Wonseok; Roh, Yongrae

    2016-07-01

    When the driving voltage of an ultrasonic transducer is increased to improve the quality of ultrasound images, heat is generated inside the transducer, which can burn the patient’s skin and degrade transducer performance. In this study, the method to disperse the heat inside an ultrasonic phased-array transducer has been examined. The mechanism of temperature rise due to heat generation inside the transducer was investigated by numerical analysis and the effects of the thermal properties of the components of the transducer such as specific heat and thermal conductivity on the temperature rise were analyzed. On the basis of the results, a heat-dispersive structure was devised to reduce the temperature at the surface of the acoustic lens of the transducer. Prototype transducers were fabricated to check the efficacy of the heat-dispersive structure. By experiments, we have confirmed that the new heat-dispersive structure can reduce the internal temperature by as much as 50% in comparison with the conventional structure, which confirms the validity of the thermal dispersion mechanism developed in this work.

  14. Inter Digital Transducer Modelling through Mason Equivalent Circuit Model

    DEFF Research Database (Denmark)

    Mishra, Dipti; Singh, Abhishek; Hussain, Dil muhammed Akbar

    2016-01-01

    The frequency reliance of inter-digital transducer is analyzed with the help of MASON’s Equivalent circuit which is based on Smith’s Equivalent circuit which is further based on Foster’sNetwork. An inter-digital transducer has been demonstratedas a RLC network. The circuit is simulated by Simulat...

  15. Inter digital transducer modelling through Mason equivalent circuit model

    DEFF Research Database (Denmark)

    Mishra, Dipti; Singh, Abhishek; Hussain, Dil muhammed Akbar

    2016-01-01

    The frequency reliance of inter-digital transducer is analyzed with the help of MASON's Equivalent circuit which is based on Smith's Equivalent circuit which is further based on Foster's Network. An inter-digital transducer has been demonstrated as a RLC network. The circuit is simulated by Simul...

  16. Metal cap flexural transducers for air-coupled ultrasonics

    Science.gov (United States)

    Eriksson, T. J. R.; Dixon, S.; Ramadas, S. N.

    2015-03-01

    Ultrasonic generation and detection in fluids is inefficient due to the large difference in acoustic impedance between the piezoelectric element and the propagation medium, leading to large internal reflections and energy loss. One way of addressing the problem is to use a flexural transducer, which uses the bending modes in a thin plate or membrane. As the plate bends, it displaces the medium in front of it, hence producing sound waves. A piezoelectric flexural transducer can generate large amplitude displacements in fluid media for relatively low excitation voltages. Commercially available flexural transducers for air applications operate at 40 kHz, but there exists ultrasound applications that require significantly higher frequencies, e.g. flow measurements. Relatively little work has been done to date to understand the underlying physics of the flexural transducer, and hence how to design it to have specific properties suitable for particular applications. This paper investigates the potential of the flexural transducer and its operating principles. Two types of actuation methods are considerd: piezoelectric and electrodynamic. The piezoelectrically actuated transducer is more energy efficient and intrinsically safe, but the electrodynamic transducer has the advantage of being less sensitive to high temperature environments. The theory of vibrating plates is used to predict transducer frequency in addition to front face amplitude, which shows good correlation with experimental results.

  17. Respiratory Belt Transducer Constructed Using a Singing Greeting Card Beeper

    Science.gov (United States)

    Bhaskar, Anand; Subramani, Selvam; Ojha, Rajdeep

    2013-01-01

    An article by Belusic and Zupancic described the construction of a finger pulse sensor using a singing greeting card beeper. These authors felt that this beeper made of piezoelectric material could be easily modified to function as a respiratory belt transducer to monitor respiratory movements. Commercially available respiratory belt transducers,…

  18. Transverse Oscillation Vector Velocity Estimation using a Phased Array Transducer

    DEFF Research Database (Denmark)

    Marcher, Jønne; Pihl, Michael Johannes; Seerup, Gert

    2012-01-01

    The Transverse Oscillation method has shown its commercial feasibility, providing the user with 2D velocity information. Todays implementation on commercial ultrasound platforms only support linear array transducers and are limited in depth. Extending the implementation to a phased array transducer...

  19. Respiratory Belt Transducer Constructed Using a Singing Greeting Card Beeper

    Science.gov (United States)

    Bhaskar, Anand; Subramani, Selvam; Ojha, Rajdeep

    2013-01-01

    An article by Belusic and Zupancic described the construction of a finger pulse sensor using a singing greeting card beeper. These authors felt that this beeper made of piezoelectric material could be easily modified to function as a respiratory belt transducer to monitor respiratory movements. Commercially available respiratory belt transducers,…

  20. A Force Transducer from a Junk Electronic Balance

    Science.gov (United States)

    Aguilar, Horacio Munguia; Aguilar, Francisco Armenta

    2009-01-01

    It is shown how the load cell from a junk electronic balance can be used as a force transducer for physics experiments. Recovering this device is not only an inexpensive way of getting a valuable laboratory tool but also very useful didactic work on electronic instrumentation. Some experiments on mechanics with this transducer are possible after a…

  1. Ultrasonic transducer with thermomechanical excitation and piezoresistive detection

    NARCIS (Netherlands)

    Popescu, Dan S.; Dascalu, Dan C.; Elwenspoek, Michael Curt; Lammerink, Theodorus S.J.

    1996-01-01

    Ultrasonic transducer was fabricated from silicon buckled membrane using a thermo mechanical excitation and piezoresistive detection. The transducer has a 4 mm square silicon membrane, buckled with an initial deflection of 20μm, actuated by dynamically heating an aluminium ring layer, 3μm thick, wit

  2. A Force Transducer from a Junk Electronic Balance

    Science.gov (United States)

    Aguilar, Horacio Munguia; Aguilar, Francisco Armenta

    2009-01-01

    It is shown how the load cell from a junk electronic balance can be used as a force transducer for physics experiments. Recovering this device is not only an inexpensive way of getting a valuable laboratory tool but also very useful didactic work on electronic instrumentation. Some experiments on mechanics with this transducer are possible after a…

  3. Top-down tree transducers with regular look-ahead

    NARCIS (Netherlands)

    Engelfriet, Joost

    1977-01-01

    Top-down tree transducers with regular look-ahead are introduced. It is shown how these can be decomposed and composed, and how this leads to closure properties of surface sets and tree transformation languages. Particular attention is paid to deterministic tree transducers.

  4. Micro-stereolithography as a transducer design method.

    Science.gov (United States)

    Ho, K S; Bradley, R J; Billson, D R; Hutchins, D A

    2008-03-01

    This paper investigates the use of micro-stereolithography, a rapid prototyping technique, in the manufacture of transducers. It is illustrated for the production of electromagnetic acoustic transducer (EMATs) coils in both meander-line and spiral configurations. A synthetic aperture focussing technique (SAFT) has been applied to the ultrasonic signals from these devices to reconstruct images in metallic objects.

  5. Energy Conversion Efficiency of Rainbow Shape Piezoelectric Transducer

    Institute of Scientific and Technical Information of China (English)

    LIU Xiangjian; CHEN Renwen; ZHU Liya

    2012-01-01

    With the aim to enhance the energy conversion efficiency of the rainbow shape piezoelectric transducer,an analysis model of energy conversion efficiency is established based on the elastic mechanics theory and piezoelectricity theory.It can be found that the energy conversion efficiency of the rainbow shape piezoelectric transducer mainly depends on its shape parameters and material properties from the analysis model.Simulation results show that there is an optimal length ratio to generate maximum energy conversion efficiency and the optimal length ratios and energy conversion efficiencies of beryllium bronze substrate transducer and steel substrate transducer are (0.65,2.21%) and (0.65,1.64%) respectively.The optimal thickness ratios and energy conversion efficiencies of beryllium bronze substrate transducer and steel substrate transducer are (1.16,2.56%) and (1.49,1.57%) respectively.With the increase of width ratio and initial curvature radius,both the energy conversion efficiencies decrease.Moreover,beryllium bronze flexible substrate transducer is superior to the steel flexible substrate transducer.

  6. Transducer hygiene: comparison of procedures for decontamination of ultrasound transducers and their use in clinical practice.

    Science.gov (United States)

    Häggström, Mikael; Spira, Jack; Edelstam, Greta

    2015-02-01

    To determine whether current hygiene practices are appropriate during sonographic examinations. Five major hospitals in Sweden were investigated with a survey. At each hospital, the departments corresponding to the main types of sonographic examination were chosen. Personnel who were responsible for or acquainted with the local hygiene procedures completed a standardardized questionnaire. The surveys were completed by 25 departments, where the total number of sonographic examinations was approximately 20,000 per month. For transvaginal and transrectal sonographic examinations, the most common method for decontamination of the transducer was barrier protection during the procedure followed by cleansing with alcohol. Latex was the predominant cover material, but one department used polyethylene gloves, and another department used nitrile gloves. Both of these involved transvaginal ultrasonography. In transcutaneous examinations, all hospitals were using alcohol and paper or cloth for decontamination at a minimum. Transesophageal examinations were carried out without barrier protection, and decontamination was performed with an alkylating substance. The hygiene practices appear to be appropriate at most hospitals, but there is a prevalence of transducer cover materials of unacceptable permeability, as well as use of gloves on transducers despite insufficient evidence of safety. © 2015 Wiley Periodicals, Inc.

  7. Durability investigation of a group of strain gage pressure transducers

    Science.gov (United States)

    Lederer, P. S.; Hilten, J. S.

    1972-01-01

    A durability investigation was conducted on a group of eighteen bonded-wire strain gage pressure transducers with ranges of 0 to 15 psig and 0 to 100 psig using an improved version of a previously developed technique. Some of the transducers were subjected to 40 million pressure cycles at a 5-Hz rate at laboratory ambient conditions, others were cycled at a temperature of 150 F (65.6 C). The largest change in sensitivity observed was 0.22% for a 100-psig transducer subjected to 40 million pressure cycles at 150 F. The largest change in zero pressure output observed was 0.91% FS for the same transducer. None of the transducers failed completely as a result of cycling at or below full scale pressure.

  8. Transducers for Sound and Vibration - FEM Based Design

    DEFF Research Database (Denmark)

    Liu, Bin

    2001-01-01

    Design of transducers for measurement of vibration (piezoelectric accelerometers) and sound (condenser microphones) is a very labour intensive work. The design work is mostly based on experience and on simple analogies to electrical circuit design. Often a time consuming itterative loop is used......: Specification of the transducer, production of a physical prototype, measurements on the prototype, changed specification of the transducer etc. Furthermore are many transducers made based on customer requirements which also increases the amount of required design work. For these reasons there is a need...... for methods that can reduce the design time consumption and the number of itterations. The present work proposes to use finite element based programs for simulating the behaviour of a transducer with a given set of specifications. A simulation program for accelerometers was developed and has been tested...

  9. Airborne Transducer Integrity under Operational Environment for Structural Health Monitoring

    Directory of Open Access Journals (Sweden)

    Mohammad Saleh Salmanpour

    2016-12-01

    Full Text Available This paper investigates the robustness of permanently mounted transducers used in airborne structural health monitoring systems, when exposed to the operational environment. Typical airliners operate in a range of conditions, hence, structural health monitoring (SHM transducer robustness and integrity must be demonstrated for these environments. A set of extreme temperature, altitude and vibration environment test profiles are developed using the existing Radio Technical Commission for Aeronautics (RTCA/DO-160 test methods. Commercially available transducers and manufactured versions bonded to carbon fibre reinforced polymer (CFRP composite materials are tested. It was found that the DuraAct transducer is robust to environmental conditions tested, while the other transducer types degrade under the same conditions.

  10. Study on electrical impedance matching for broadband ultrasonic transducer

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Geon Woo [University of Science and Technology, Daejeon (Korea, Republic of); Kim, Ki Bok [Korea Research Institute of Standards and Science, Center for Safety Measurement, Daejeon (Korea, Republic of); Baek, Kwang Sae [Elache Co., Busan (Korea, Republic of)

    2017-02-15

    Ultrasonic transducers with high resolution and resonant frequency are required to detect small defects (less than hundreds of μm) by ultrasonic testing. The resonance frequency and resolution of an ultrasonic transducer are closely related to the thickness of piezo-electric materials, backing materials, and the electric impedance matching technique. Among these factors, electrical impedance matching plays an important role because it can reduce the loss and reflection of ultrasonic energy differences in electrical impedance between an ultrasonic transducer and an ultrasonic defects detecting system. An LC matching circuit is the most frequently used electric matching method. It is necessary for the electrical impedance of an ultrasonic transducer to correspond to approximately 50 Ω to compensate the difference in electrical impedance between both connections. In this study, a 15 MHz immersion ultrasonic transducer was fabricated and an LC electrical impedance circuit was applied to that for having broad-band frequency characteristic.

  11. Study on the broadband tonpilz transducer with a single hole.

    Science.gov (United States)

    Xiping, He; Jing, Hu

    2009-05-01

    To get a wide-band transducer, the piezoelectric sandwiched transducer with a frustum hole in its head piece is presented in this paper. The equivalent circuit is derived, and the expressions of the equivalent mass and the equivalent impedance of the transducer are obtained by using one-dimensional (1D) design theory. Moreover, the expressions of the mechanical quality factor and the frequency bandwidth are obtained and the transmitting voltage response of the transducer is calculated by using finite element method. The theoretical results show that the frequency bandwidth of the transducer with a hole is wider than that without a hole when their resonant frequencies are almost equal. The tested results are in good agreement with the theoretical calculations.

  12. Piezoelectric single crystals for ultrasonic transducers in biomedical applications

    Science.gov (United States)

    Zhou, Qifa; Lam, Kwok Ho; Zheng, Hairong; Qiu, Weibao; Shung, K. Kirk

    2014-01-01

    Piezoelectric single crystals, which have excellent piezoelectric properties, have extensively been employed for various sensors and actuators applications. In this paper, the state–of–art in piezoelectric single crystals for ultrasonic transducer applications is reviewed. Firstly, the basic principles and design considerations of piezoelectric ultrasonic transducers will be addressed. Then, the popular piezoelectric single crystals used for ultrasonic transducer applications, including LiNbO3 (LN), PMN–PT and PIN–PMN–PT, will be introduced. After describing the preparation and performance of the single crystals, the recent development of both the single–element and array transducers fabricated using the single crystals will be presented. Finally, various biomedical applications including eye imaging, intravascular imaging, blood flow measurement, photoacoustic imaging, and microbeam applications of the single crystal transducers will be discussed. PMID:25386032

  13. Ultrasound transducer positioning aid for fetal heart rate monitoring.

    Science.gov (United States)

    Hamelmann, Paul; Kolen, Alex; Schmitt, Lars; Vullings, Rik; van Assen, Hans; Mischi, Massimo; Demi, Libertario; van Laar, Judith; Bergmans, Jan

    2016-08-01

    Fetal heart rate (fHR) monitoring is usually performed by Doppler ultrasound (US) techniques. For reliable fHR measurements it is required that the fetal heart is located within the US beam. In clinical practice, clinicians palpate the maternal abdomen to identify the fetal presentation and then the US transducer is fixated on the maternal abdomen where the best fHR signal can be obtained. Finding the optimal transducer position is done by listening to the strength of the Doppler audio output and relying on a signal quality indicator of the cardiotocographic (CTG) measurement system. Due to displacement of the US transducer or displacement of the fetal heart out of the US beam, the fHR signal may be lost. Therefore, it is often necessary that the obstetrician repeats the tedious procedure of US transducer positioning to avoid long periods of fHR signal loss. An intuitive US transducer positioning aid would be highly desirable to increase the work flow for the clinical staff. In this paper, the possibility to determine the fetal heart location with respect to the transducer by exploiting the received signal power in the transducer elements is shown. A commercially available US transducer used for fHR monitoring is connected to an US open platform, which allows individual driving of the elements and raw US data acquisition. Based on the power of the received Doppler signals in the transducer elements, the fetal heart location can be estimated. A beating fetal heart setup was designed and realized for validation. The experimental results show the feasibility of estimating the fetal heart location with the proposed method. This can be used to support clinicians in finding the optimal transducer position for fHR monitoring more easily.

  14. Dynamics of electromagnetically-transduced microresonators

    Science.gov (United States)

    Sabater, Andrew B.

    Electromagnetic transduction is a means of actuating and sensing microelectromechanical systems (MEMS) through the interaction of electric and magnetic fields. Electromagnetically-transduced devices are Lorentz force actuated and sensed via an induced electromotive force (EMF). As such, transduction requires that the vibrations of one of these devices take place within a magnetic field. Provided one can leverage relatively recent advances with rare-earth magnets or complementary metal-oxide-semiconductor (CMOS) fabrication for magnetic field generation, electromagnetic transduction offers many distinct advantages over other methods of actuating and sensing MEMS. These advantages include the ability to generate large forces and moments that are linearly related to the supplied current, comparatively low power consumption metrics obtained with comparatively-low excitation voltages, and comparatively-simple device geometries that do not interfere with transduction. This type of transduction also facilitates operation in fluidic or harsh environments. In addition, an electromagnetically-transduced microresonator (ETM) could be used in the future for numerous applications which utilize a microresonator, such as electrical signal processing and resonant-based mass sensing, as well as self-sustaining oscillators. Other potential applications that are relatively unique to ETMs are a product of electromagnetic transduction, like magnetic field sensing. Arrays of electromagnetically-transduced devices could also be used to improve a sensor's throughput, or the total amount of sensed information, as it is comparatively-easy to electrically-couple multiple devices together. The efforts associated with the design, fabrication and characterization in both low-pressure and atmospheric conditions of one such array that has multiple, easily-tailored resonances with single-input, single-output (SISO) characteristics are documented in this dissertation. This type of electromagnetic

  15. Dual-frequency transducer for nonlinear contrast agent imaging.

    Science.gov (United States)

    Guiroy, Axel; Novell, Anthony; Ringgaard, Erling; Lou-Moeller, Rasmus; Grégoire, Jean-Marc; Abellard, André-Pierre; Zawada, Tomasz; Bouakaz, Ayache; Levassort, Franck

    2013-12-01

    Detection of high-order nonlinear components issued from microbubbles has emerged as a sensitive method for contrast agent imaging. Nevertheless, the detection of these high-frequency components, including the third, fourth, and fifth harmonics, remains challenging because of the lack of transducer sensitivity and bandwidth. In this context, we propose a new design of imaging transducer based on a simple fabrication process for high-frequency nonlinear imaging. The transducer is composed of two elements: the outer low-frequency (LF) element was centered at 4 MHz and used in transmit mode, whereas the inner high-frequency (HF) element centered at 14 MHz was used in receive mode. The center element was pad-printed using a lead zirconate titanate (PZT) paste. The outer element was molded using a commercial PZT, and curved porous unpoled PZT was used as backing. Each piezoelectric element was characterized to determine the electromechanical performance with thickness coupling factor around 45%. After the assembly of the two transducer elements, hydrophone measurements (electroacoustic responses and radiation patterns) were carried out and demonstrated a large bandwidth (70% at -3 dB) of the HF transducer. Finally, the transducer was evaluated for contrast agent imaging using contrast agent microbubbles. The results showed that harmonic components (up to the sixth harmonic) of the microbubbles were successfully detected. Moreover, images from a flow phantom were acquired and demonstrated the potential of the transducer for high-frequency nonlinear contrast imaging.

  16. Design of advanced ultrasonic transducers for welding devices.

    Science.gov (United States)

    Parrini, L

    2001-11-01

    A new high frequency ultrasonic transducer has been conceived, designed, prototyped, and tested. In the design phase, an advanced approach was used and established. The method is based on an initial design estimate obtained with finite element method (FEM) simulations. The simulated ultrasonic transducers and resonators are then built and characterized experimentally through laser interferometry and electrical resonance spectra. The comparison of simulation results with experimental data allows the parameters of FEM models to be adjusted and optimized. The achieved FEM simulations exhibit a remarkably high predictive potential and allow full control of the vibration behavior of the transducer. The new transducer is mounted on a wire bonder with a flange whose special geometry was calculated by means of FEM simulations. This flange allows the transducer to be attached on the wire bonder, not only in longitudinal nodes, but also in radial nodes of the ultrasonic field excited in the horn. This leads to a total decoupling of the transducer to the wire bonder, which has not been achieved so far. The new approach to mount ultrasonic transducers on a welding device is of major importance, not only for wire bonding, but also for all high power ultrasound applications and has been patented.

  17. TRANSDUCER GENERATED ARRAYS OF ROBOTIC NANO-ARMS.

    Science.gov (United States)

    Dolzhenko, Egor; Jonoska, Nataša; Seeman, Nadrian C

    2010-06-01

    We consider sets of two-dimensional arrays, called here transducer generated languages, obtained by iterative applications of transducers (finite state automata with output). Each transducer generates a set of blocks of symbols such that the bottom row of a block is an input string accepted by the transducer and, by iterative application of the transducer, each row of the block is an output of the transducer on the preceding row. We show how these arrays can be implemented through molecular assembly of triple crossover DNA molecules. Such assembly could serve as a scaffold for arranging molecular robotic arms capable for simultaneous movements. We observe that transducer generated languages define a class of languages which is a proper subclass of recognizable picture languages, but it containing the class of all factorial local two-dimensional languages. By taking the average growth rate of the number of blocks in the language as a measure of its complexity, we further observe that arrays with high complexity patterns can be generated in this way.

  18. Design, analysis, and modeling of giant magnetostrictive transducers

    Science.gov (United States)

    Calkins, Frederick Theodore

    The increased use of giant magnetostrictive, Terfenol-D transducers in a wide variety of applications has led to a need for greater understanding of the materials performance. This dissertation attempts to add to the Terfenol-D transducer body of knowledge by providing an in-depth analysis and modeling of an experimental transducer. A description of the magnetostriction process related to Terfenol-D includes a discussion of material properties, production methods, and the effect of mechanical stress, magnetization, and temperature on the material performance. The understanding of the Terfenol-D material performance provides the basis for an analysis of the performance of a Terfenol-D transducer. Issues related to the design and utilization of the Terfenol-D material in the transducers are considered, including the magnetic circuit, application of mechanical prestress, and tuning of the mechanical resonance. Experimental results from two broadband, Tonpilz design transducers show the effects of operating conditions (prestress, magnetic bias, AC magnetization amplitude, and frequency) on performance. In an effort to understand and utlilize the rich performance space described by the experimental results a variety of models are considered. An overview of models applicable to Terfenol-D and Terfenol-D transducers is provided, including a discussion of modeling criteria. The Jiles-Atherton model of ferromagnetic hysteresis is employed to describe the quasi-static transducer performance. This model requires the estimation of only six physically-based parameters to accurately simulate performance. The model is shown to be robust with respect to model parameters over a range of mechanical prestress, magnetic biases, and AC magnetic field amplitudes, allowing predictive capability within these ranges. An additional model, based on electroacoustics theory, explains trends in the frequency domain and facilitates an analysis of efficiency based on impedance and admittance

  19. Bonding and impedance matching of acoustic transducers using silver epoxy.

    Science.gov (United States)

    Son, Kyu Tak; Lee, Chin C

    2012-04-01

    Silver epoxy was selected to bond transducer plates on glass substrates. The properties and thickness of the bonding medium affect the electrical input impedance of the transducer. Thus, the thickness of the silver epoxy bonding layer was used as a design parameter to optimize the structure for the transducer input impedance to match the 50 Ω output impedance of most radio frequency (RF) generators. Simulation and experimental results show that nearly perfect matching is achieved without using any matching circuit. At the matching condition, the transducer operates at a frequency band a little bit below the half-wavelength resonant frequency of the piezoelectric plate. In experiments, lead titanate (PT) piezoelectric plates were employed. Both full-size, 11.5 mm × 2 mm × 0.4 mm, and half-size, 5.75 mm × 2 mm × 0.4 mm, can be well matched using optimal silver epoxy thickness. The transducer assemblies demonstrate high efficiency. The conversion loss from electrical power to acoustic power in soda-lime glass is 4.3 dB. This loss is low considering the fact that the transducers operate at off-resonance by 12%. With proper choice of silver epoxy thickness, the transducer can be matched at the fundamental, the 3rd and 5th harmonic frequencies. This leads to the possible realization of triple-band transducers. Reliability was assessed with thermal cycling test according to Telcordia GR-468-Core recommendation. Of the 30 transducer assemblies tested, none broke until 2900 cycles and 27 have sustained beyond 4050 cycles.

  20. USE OF PELTIER COOLERS AS SOIL HEAT FLUX TRANSDUCERS.

    Science.gov (United States)

    Weaver, H.L.; Campbell, G.S.

    1985-01-01

    Peltier coolers were modified and calibrated to serve as soil heat flux transducers. The modification was to fill their interiors with epoxy. The average calibration constant on 21 units was 13. 6 plus or minus 0. 8 kW m** minus **2 V** minus **1 at 20 degree C. This sensitivity is about eight times that of the two thermopile transducers with which comparisons were made. The thermal conductivity of the Peltier cooler transducers was 0. 4 W m** minus **1 degree C** minus **1, which is comparable to that of dry soil.

  1. Dynamic mechanism and its modelling of micromachined electrostatic ultrasonic transducers

    Institute of Scientific and Technical Information of China (English)

    葛立峰

    1999-01-01

    A tensile-plate-on-air-spring model (or called TDK model for short) for micromachined electrostatic ultrasonic transducers has been developed based on a thorough investigation of their dynamic mechanism. The mechanical stiffness effects caused by the compressibility of air gaps, bending stiffness of the diaphragm and in-plane tension applied to the diaphragm, together with an electrostatic negative stiffness effect are included completely in the model. Desired particular fundamental frequency and bandwidth can be obtained by only properly tailoring the geometry, dimensions and materials of transducers according to the model, which provides thereby a reliable theoretical basis for the understanding and optimised design of such transducers.

  2. A thermal insulation method for a piezoelectric transducer

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    This study deals with the sources of signal distortion of a piezoelectric transducer heated by measured gas flow. These signal distortions originate from both unloading of preload on a piezocrystal because of expansion of a diaphragm in the test apparatus and the pyroelectric effect of a heated piezoelectric crystal. A plastic film on the diaphragm of the transducer can effectively insulate the diaphragm and the piezocrystal within transducer from heating by gas flow, eliminating the sources of distortion. A method for evaluating the thickness of the film is proposed.

  3. Optimization of ultrasonic transducers for selective guided wave actuation

    Science.gov (United States)

    Miszczynski, Mateusz; Packo, Pawel; Zbyrad, Paulina; Stepinski, Tadeusz; Uhl, Tadeusz; Lis, Jerzy; Wiatr, Kazimierz

    2016-04-01

    The application of guided waves using surface-bonded piezoceramic transducers for nondestructive testing (NDT) and Structural Health Monitoring (SHM) have shown great potential. However, due to difficulty in identification of individual wave modes resulting from their dispersive and multi-modal nature, selective mode excitement methods are highly desired. The presented work focuses on an optimization-based approach to design of a piezoelectric transducer for selective guided waves generation. The concept of the presented framework involves a Finite Element Method (FEM) model in the optimization process. The material of the transducer is optimized in topological sense with the aim of tuning piezoelectric properties for actuation of specific guided wave modes.

  4. Broadband tonpilz underwater acoustic transducers based on multimode optimization

    DEFF Research Database (Denmark)

    Yao, Qingshan; Jensen, Leif Bjørnø

    1997-01-01

    Head flapping has often been considered to be deleterious for obtaining a tonpilz transducer with broadband, high power performance. In the present work, broadband, high power tonpilz transducers have been designed using the finite element (FE) method. Optimized vibrational modes including...... the flapping mode of the head are effectively used to achieve the broadband performance. The behavior of the transducer in its longitudinal piston mode and in its flapping mode is analysed for in-air and in-water situations. For the 37.8% bandwidth of the center frequency from 28.5 to 41.8 kHz, the amplitude...

  5. Design and fabrication of a low frequency giant magnetostrictive transducer

    Energy Technology Data Exchange (ETDEWEB)

    Dhilsha, K.R. [Nat. Inst. of Ocean Technol, Madras (India); Markandeyulu, G.; Subrahmanyeswara Rao, B.V.P.; Rama Rao, K.V.S. [Magnetism and Magnetic Materials Laboratory, Department of Physics, Indian Institute of Technology, Madras 600 036 (India)

    1997-08-01

    A Tonpilz-type single ended transducer employing two rods of giant magnetostrictive materials has been fabricated and its underwater acoustic characteristics have been studied. The transducer resonated at a frequency of 3.1 kHz in air and at 2.65 kHz in water with a Q factor of 6. The TCR and RS at resonance in water have been measured to be 172.1 dB re 1 {mu}Pa/A at 1 m and -196.7 dB re 1 V/{mu}Pa respectively. The dimensions of the transducer are 60 mm in diameter and 110 mm long. (orig.)

  6. Ultrasonic Transducer Peak-to-Peak Optical Measurement

    Directory of Open Access Journals (Sweden)

    Pavel Skarvada

    2012-01-01

    Full Text Available Possible optical setups for measurement of the peak-to-peak value of an ultrasonic transducer are described in this work. The Michelson interferometer with the calibrated nanopositioner in reference path and laser Doppler vibrometer were used for the basic measurement of vibration displacement. Langevin type of ultrasonic transducer is used for the purposes of Electro-Ultrasonic Nonlinear Spectroscopy (EUNS. Parameters of produced mechanical vibration have to been well known for EUNS. Moreover, a monitoring of mechanical vibration frequency shift with a mass load and sample-transducer coupling is important for EUNS measurement.

  7. Broadband electrical impedance matching for piezoelectric ultrasound transducers.

    Science.gov (United States)

    Huang, Haiying; Paramo, Daniel

    2011-12-01

    This paper presents a systematic method for designing broadband electrical impedance matching networks for piezoelectric ultrasound transducers. The design process involves three steps: 1) determine the equivalent circuit of the unmatched piezoelectric transducer based on its measured admittance; 2) design a set of impedance matching networks using a computerized Smith chart; and 3) establish the simulation model of the matched transducer to evaluate the gain and bandwidth of the impedance matching networks. The effectiveness of the presented approach is demonstrated through the design, implementation, and characterization of impedance matching networks for a broadband acoustic emission sensor. The impedance matching network improved the power of the acquired signal by 9 times.

  8. L-band orthomode transducer for the Sardinia Radio Telescope

    Science.gov (United States)

    Navarrini, Alessandro; Pisanu, Tonino

    2008-07-01

    We describe the design, construction, and characterization results of a compact L-band (1.3-1.8 GHz) Orthomode Transducer (OMT) for the Sardinia Radio Telescope (SRT), a 64 m diameter telescope which is being built in the Sardinia island, Italy. The OMT consists of three distinct mechanical parts connected through ultra low loss coaxial cables: a turnstile junction and two identical 180° hybrid power combiners. The turnstile junction is based on a circular waveguide input (diameter of 190 mm,) and on four WR650 rectangular waveguide cavities from which the RF signals are extracted using coaxial probes. The OMT was optimized using a commercial 3D electromagnetic simulator. The main mechanical part of the turnstile junction was machined out of an Aluminum block whose final external shape is a cylinder with diameter 450 mm and height 98 mm. From 1.3 to 1.8 GHz the measured reflection coefficient was less than -22 dB, the isolation between the outputs was less than -45 dB, and the cross polarization was less than -50 dB for both polarization channels.

  9. Electromechanically active polymer transducers: research in Europe

    Science.gov (United States)

    Carpi, Federico; Graz, Ingrid; Jager, Edwin; Ladegaard Skov, Anne; Vidal, Frédéric

    2013-10-01

    Smart materials and structures based on electromechanically active polymers (EAPs) represent a fast growing and stimulating field of research and development. EAPs are materials capable of changing dimensions and/or shape in response to suitable electrical stimuli. They are commonly classified in two major families: ionic EAPs (activated by an electrically induced transport of ions and/or solvent) and electronic EAPs (activated by electrostatic forces). These polymers show interesting properties, such as sizable active strains and/or stresses in response to electrical driving, high mechanical flexibility, low density, structural simplicity, ease of processing and scalability, no acoustic noise and, in most cases, low costs. Since many of these characteristics can also describe natural muscle tissues from an engineering standpoint, it is not surprising that EAP transducers are sometimes also referred to as 'muscle-like smart materials' or 'artificial muscles'. They are used not only to generate motion, but also to sense or harvest energy from it. In particular, EAP electromechanical transducers are studied for applications that can benefit from their 'biomimetic' characteristics, with possible usages from the micro- to the macro-scale, spanning several disciplines, such as mechatronics, robotics, automation, biotechnology and biomedical engineering, haptics, fluidics, optics and acoustics. Currently, the EAP field is just undergoing its initial transition from academic research into commercialization, with companies starting to invest in this technology and the first products appearing on the market. This focus issue is intentionally aimed at gathering contributions from the most influential European groups working in the EAP field. In fact, today Europe hosts the broadest EAP community worldwide. The rapid expansion of the EAP field in Europe, where it historically has strong roots, has stimulated the creation of the 'European Scientific Network for Artificial

  10. Wideband Single Crystal Transducer for Bone Characterization Project

    Data.gov (United States)

    National Aeronautics and Space Administration — TRS proposes to develop a simple-to-use, launch capable, ultrasound transducer that is capable of producing the necessary bandwidth to accurately determine in vivo...

  11. Integration of Capacitive Micromachined Ultrasound Transducers to Microfluidic Devices

    KAUST Repository

    Viržonis, Darius

    2013-10-22

    The design and manufacturing flexibility of capacitive micromachined ultrasound transducers (CMUT) makes them attractive option for integration with microfluidic devices both for sensing and fluid manipulation. CMUT concept is introduced here by presentin

  12. Performance Evaluation of Pressure Transducers for Water Impacts

    Science.gov (United States)

    Vassilakos, Gregory J.; Stegall, David E.; Treadway, Sean

    2012-01-01

    The Orion Multi-Purpose Crew Vehicle is being designed for water landings. In order to benchmark the ability of engineering tools to predict water landing loads, test programs are underway for scale model and full-scale water impacts. These test programs are predicated on the reliable measurement of impact pressure histories. Tests have been performed with a variety of pressure transducers from various manufacturers. Both piezoelectric and piezoresistive devices have been tested. Effects such as thermal shock, pinching of the transducer head, and flushness of the transducer mounting have been studied. Data acquisition issues such as sampling rate and anti-aliasing filtering also have been studied. The response of pressure transducers have been compared side-by-side on an impulse test rig and on a 20-inch diameter hemisphere dropped into a pool of water. The results have identified a range of viable configurations for pressure measurement dependent on the objectives of the test program.

  13. Transducer for Tension Force Measuring of Strip Materials

    Directory of Open Access Journals (Sweden)

    Emad S. Addasi

    2005-01-01

    Full Text Available In winding-up motor drive systems, such as that used in textile industry, it is very important to get a constant tension force for the winding strip material (thread and to reduce its oscillations. This study recommends a transducer with a special design to be used in the mentioned motor drive systems. By using a piston damper, spring, levers, slider and other simple components the suggested sensor (transducer can be used to control the motor speed for getting the required thread tension force. Also the suggested transducer avoids the disadvantage of other used conventional transducer: the parasitic (detrimental oscillations of the thread tension force, which affect the quality of the produced strip material.

  14. Spatial impulse response of a rectangular double curved transducer

    DEFF Research Database (Denmark)

    Bæk, David; Jensen, Jørgen Arendt; Willatzen, Morten

    2012-01-01

    Calculation of the pressure field from transducers having both a convex and a concave surface geometry is a complicated assignment that often is accomplished by subdividing the transducer surface into smaller flat elements of which the spatial impulse response is known. This method is often seen...... applied to curved transducers because an analytical solution is un-known. In this work a semi-analytical algorithm for the exact solution to a first order in diffraction effect of the spatial impulse response of rectangular shaped double curved transducers is presented. The algorithm and an approximation...... approximations ranging from 0.03 % to 0.8 % relative to a numerical solution for the spatial impulse response. It is shown that the presented algorithm gives consistent results with Field II for a linear flat, a linear focused, and a convex non-focused element. Best solution was found to be 0.01 % with a three...

  15. Studies on coaxial circular array for underwater transducer applications

    Digital Repository Service at National Institute of Oceanography (India)

    Chakraborty, B.

    This thesis presents analytical methods to study important aspects of a coaxial circular array for wideband underwater transducer application. It begins with detailed theoretical study of a coaxial circular array of three turns and an analysis...

  16. Photoacoustic tomography of monkey brain using virtual point ultrasonic transducers.

    Science.gov (United States)

    Nie, Liming; Guo, Zijian; Wang, Lihong V

    2011-07-01

    A photoacoustic tomography system (PAT) using virtual point ultrasonic transducers was developed and applied to image a monkey brain. The custom-built transducers provide a 10-fold greater field-of-view (FOV) than finite-aperture unfocused transducers as well as an improved signal-to-noise ratio (SNR) and reduced artifacts rather than negative-lens transducers. Their tangential resolution, radial resolution, and (SNR) improvements were quantified using tissue phantoms. Our PAT system can achieve high uniformity in both resolution (8) within a large FOV of 6 cm in diameter, even when the imaging objects are enclosed by a monkey skull. The cerebral cortex of a monkey brain was accurately mapped transcranially, through a skull ranging from 2 to 4 mm in thickness. This study demonstrates that PAT can overcome the optical and ultrasound attenuation of a relatively thick skull and can potentially be applied to human neonatal brain imaging.

  17. Lithium niobate ultrasonic transducer design for Enhanced Oil Recovery.

    Science.gov (United States)

    Wang, Zhenjun; Xu, Yuanming; Gu, Yuting

    2015-11-01

    Due to the strong piezoelectric effect possessed by lithium niobate, a new idea that uses lithium niobate to design high-power ultrasonic transducer for Enhanced Oil Recovery technology is proposed. The purpose of this paper is to lay the foundation for the further research and development of high-power ultrasonic oil production technique. The main contents of this paper are as follows: firstly, structure design technique and application of a new high-power ultrasonic transducer are introduced; secondly, the experiment for reducing the viscosity of super heavy oil by this transducer is done, the optimum ultrasonic parameters for reducing the viscosity of super heavy oil are given. Experimental results show that heavy large molecules in super heavy oil can be cracked into light hydrocarbon substances under strong cavitation effect caused by high-intensity ultrasonic wave. Experiment proves that it is indeed feasible to design high-power ultrasonic transducer for ultrasonic oil production technology using lithium niobate.

  18. Finite element analysis for acoustic characteristics of a magnetostrictive transducer

    Science.gov (United States)

    Kim, Jaehwan; Jung, Eunmi

    2005-12-01

    This paper presents a finite element analysis for a magnetostrictive transducer by taking into account the nonlinear behavior of the magnetostrictive material and fluid interaction. A finite element formulation is derived for the coupling of magnetostrictive and elastic materials based upon a separated magnetic and displacement field calculation and a curve fitting technique of material properties. The fluid and structure coupled problem is taken into account based upon pressure and velocity potential fields formulation. Infinite wave envelope elements are introduced at an artificial boundary to deal with the infinite fluid domain. A finite element code for the analysis of a magnetostrictive transducer is developed. A magnetostrictive tonpilz transducer is taken as an example and verification for the developed program is made by comparing with a commercial code. The acoustic characteristics of the magnetostrictive tonpilz transducer are calculated in terms of radiation pattern and transmitted current response.

  19. Traceable dynamic calibration of force transducers by primary means

    Science.gov (United States)

    Vlajic, Nicholas; Chijioke, Ako

    2016-08-01

    We describe an apparatus for traceable, dynamic calibration of force transducers using harmonic excitation, and report calibration measurements of force transducers using this apparatus. In this system, the force applied to the transducer is produced by the acceleration of an attached mass, and is determined according to Newton’s second law, F  =  ma. The acceleration is measured by primary means, using laser interferometry. The capabilities of this system are demonstrated by performing dynamic calibrations of two shear-web-type force transducers up to a frequency of 2 kHz, with an expanded uncertainty below 1.2%. We give an account of all significant sources of uncertainty, including a detailed consideration of the effects of dynamic tilting (rocking), which is a leading source of uncertainty in such harmonic force calibration systems.

  20. Tunable interdigital transducers made of piezoelectric macro-fiber composite

    Science.gov (United States)

    Mańka, Michał; Martowicz, Adam; Rosiek, Mateusz; Stepinski, Tadeusz; Uhl, Tadeusz

    2016-11-01

    The number of applications of Lamb waves (LWs) based structural health monitoring (SHM) has significantly increased in recent decades. The growth of interest results from several advantages of this diagnostic technique, that is, considerable mode selectivity and directivity that allow for the assessment of the technical condition of a monitored structure. Successful applications of LWs in the field of SHM stimulate continuous improvement of the transducers’ design to enable capturing more reliable diagnostic data. The paper introduces a new type of transducer that may be used in the LWs based SHM systems, namely tunable-interdigital transducer (T-IDT) based on macro-fiber composites (MFC). The authors provide a short overview on different types of transducers that may be used in SHM applications, followed by a detailed description of the structure of proposed T-IDT. Finally, the results of numerical and experimental tests carried out employing the proposed transducer are discussed and compared to those obtained with a traditional IDT.

  1. Phylocomposer and phylodirector: analysis and visualization of transducer indel models.

    Science.gov (United States)

    Holmes, Ian

    2007-12-01

    Finite-state string transducers are probabilistic tools similar to Hidden Markov Models that can be systematically extended to large number of sequences related by indel and substitution processes on phylogenetic trees. The number of states in such models grows exponentially with the number of nodes in the tree, with the consequence that even quite small trees can be difficult to analyze or visualize. Here, we present two tools, phylocomposer and phylodirector, for working with string transducers. The former tool implements previously described composition algorithms for extending transducers to arbitrary tree topologies, while the latter generates short animations for arbitrary input alignments and phylogenetic trees, illustrating the state path through the composed transducer. Phylocomposer and phylodirector are freely available at http://biowiki.org/PhyloComposer and http://biowiki.org/PhyloDirector

  2. A Novel Drive Option for Piezoelectric Ultrasonic Transducers

    OpenAIRE

    Diana Engelke; Bernd Oehme; Jens Strackeljan

    2011-01-01

    This paper concentrates on ultrasonic transducers, which are driven by piezoelectric ceramic rings that are arranged in a stack. A novel drive option, where the stack contains a new type of divided piezoelectric rings, is analyzed using the finite element method, prototyped, and tested. To gain a better sense of the vibration behavior, the studies focus initially on one ring and subsequently on the different possibilities to assemble the transducer. The investigations point out that natural b...

  3. Lead-Free Piezoelectric Transducers for Microelectronic Wirebonding Applications

    OpenAIRE

    Kwok, K.W.; T. Lee; Choy, S. H.; Chan, H.L.W.

    2010-01-01

    Lead-free KNLNTS and BNKLBT piezoelectric ceramic rings have been successfully prepared and used as the driving elements for fabricating ultrasonic wirebonding transducers. In order to improve the energy transfer between different parts of the transducer, titanium alloy has been used to fabricate the front and back plates. The dimensions of the ceramic rings and the titanium alloy plates have been optimized to give an operation frequency of 65 kHz. Because of the better matching of the acoust...

  4. Capacitive Ultrasonic Transducer Development for Acoustic Anemometry on Mars

    Science.gov (United States)

    Leonard-Pugh, Eurion; Wilson, C.; Calcutt, S.; Davis, L.

    2012-10-01

    Previous Mars missions have used either mechanical or thermal anemometry techniques. The moving parts of mechanical anemometers are prone to damage during launch and landing and their inertia makes them unsuited for turbulence studies. Thermal anemometers have been used successfully on Mars but are difficult to calibrate and susceptible to varying ambient temperatures. In ultrasonic anemometry, wind speed and sound speed are calculated from two-way time-of-flight measurements between pairs of transducers; three pairs of transducers are used to return a 3-D wind vector. These high-frequency measurements are highly reliable and immune from drift. Piezo-electric ultrasonic anemometers are widely used on Earth due to their full-range accuracy and high measurement frequency. However these transducers have high acoustic impedances and would not work on Mars. We are developing low-mass capacitive ultrasonic transducers for Mars missions which have significantly lower acoustic impedances and would therefore have a much stronger coupling to the Martian atmosphere. These transducers consist of a metallised polymer film pulled taught against a machined metal backplane. The film is drawn towards the backplane by a DC bias voltage. A varying signal is used on top of the DC bias to oscillate the film; generating acoustic waves. This poster will look at the operation of such sensors and the developments necessary to operate the devices under Martian conditions. Transducer performance is determined primarily by two elements; the front film and the backplane. The sensitivity of the transducer is affected by the thickness of the front film; as well as the diameter, curvature and roughness of the metal backplane. We present data on the performance of the sensors and instrument design considerations including signal shapes and transducer arrangements.

  5. Finite-State Complexity and the Size of Transducers

    Directory of Open Access Journals (Sweden)

    Cristian Calude

    2010-08-01

    Full Text Available Finite-state complexity is a variant of algorithmic information theory obtained by replacing Turing machines with finite transducers. We consider the state-size of transducers needed for minimal descriptions of arbitrary strings and, as our main result, we show that the state-size hierarchy with respect to a standard encoding is infinite. We consider also hierarchies yielded by more general computable encodings.

  6. Ionic solvents used in ionic polymer transducers, sensors and actuators

    OpenAIRE

    2004-01-01

    Ionic liquids are incorporated into transducers, actuators or sensors which employ the ionic polymer membranes. The ionic liquids have superior electrochemical stability, low viscosity and low vapor pressure. The transducers, actuators and sensors which utilize ionic polymer membranes solvated with ionic liquids have long term air stability. Superior results are achieved when a conductive powder and ionomer mixture is applied to the ionic polymer membrane to form the electrodes during or afte...

  7. Oblong-Shaped-Focused Transducers for Intravascular Ultrasound Imaging.

    Science.gov (United States)

    Lee, Junsu; Jang, Jihun; Chang, Jin Ho

    2017-03-01

    In intravascular ultrasound (IVUS) imaging, a transducer is inserted into a blood vessel and rotated to obtain image data. For this purpose, the transducer aperture is typically less than 0.5 mm in diameter, which causes natural focusing to occur in the imaging depth ranging from 1 to 5 mm. Due to the small aperture, however, it is not viable to conduct geometric focusing in order to enhance the spatial resolution of IVUS images. Furthermore, this hampers narrowing the slice thickness of a cross-sectional scan plane in the imaging depth, which leads to lowering spatial and contrast resolutions of IVUS images. To solve this problem, we propose an oblong-shaped-focused transducer for IVUS imaging. Unlike the conventional IVUS transducers with either a circular or a square flat aperture, the proposed transducer has an oblong aperture of which long side is positioned along a blood vessel. This unique configuration makes it possible to conduct geometric focusing at a desired depth in the elevation direction. In this study, furthermore, it is demonstrated that a spherically shaped aperture in both lateral and elevation directions also improves lateral resolution, compared to the conventional flat aperture. To ascertain this, the conventional and the proposed IVUS transducers were designed and fabricated to evaluate and to compare their imaging performances through wire phantom and tissue-mimicking phantom experiments. For the proposed 50-MHz IVUS transducer, a PZT piece of 0.5 × 1.0 mm(2) was spherically shaped for elevation focus at 3 mm by using the conventional press-focusing technique whereas the conventional one has a flat aperture of 0.5 × 0.5 mm(2). The experimental results demonstrated that the proposed IVUS transducer is capable of improving spatial and contrast resolutions of IVUS images.

  8. Method and apparatus for air-coupled transducer

    Science.gov (United States)

    Song, Junho (Inventor); Chimenti, Dale E. (Inventor)

    2010-01-01

    An air-coupled transducer includes a ultrasonic transducer body having a radiation end with a backing fixture at the radiation end. There is a flexible backplate conformingly fit to the backing fixture and a thin membrane (preferably a metallized polymer) conformingly fit to the flexible backplate. In one embodiment, the backing fixture is spherically curved and the flexible backplate is spherically curved. The flexible backplate is preferably patterned with pits or depressions.

  9. Micromachining of a piezocomposite transducer using a copper vapor laser.

    Science.gov (United States)

    Farlow, R; Galbraith, W; Knowles, M; Hayward, G

    2001-05-01

    A 1-3 piezocomposite transducer with front face dimensions of 2 x 2 mm has been micromachined using a copper vapor laser. The device consists of PZT5A piezoceramic pillars with a 65-micron pitch suspended in a low viscosity thermosetting polymer. The kerf width is 13 microns, and the transducer thickness is 170 microns, making the device suitable for ultrasonic reception at frequencies close to 10 MHz.

  10. Home Automation System Based on Intelligent Transducer Enablers

    Science.gov (United States)

    Suárez-Albela, Manuel; Fraga-Lamas, Paula; Fernández-Caramés, Tiago M.; Dapena, Adriana; González-López, Miguel

    2016-01-01

    This paper presents a novel home automation system named HASITE (Home Automation System based on Intelligent Transducer Enablers), which has been specifically designed to identify and configure transducers easily and quickly. These features are especially useful in situations where many transducers are deployed, since their setup becomes a cumbersome task that consumes a significant amount of time and human resources. HASITE simplifies the deployment of a home automation system by using wireless networks and both self-configuration and self-registration protocols. Thanks to the application of these three elements, HASITE is able to add new transducers by just powering them up. According to the tests performed in different realistic scenarios, a transducer is ready to be used in less than 13 s. Moreover, all HASITE functionalities can be accessed through an API, which also allows for the integration of third-party systems. As an example, an Android application based on the API is presented. Remote users can use it to interact with transducers by just using a regular smartphone or a tablet. PMID:27690031

  11. Exact series model of Langevin transducers with internal losses.

    Science.gov (United States)

    Nishamol, P A; Ebenezer, D D

    2014-03-01

    An exact series method is presented to analyze classical Langevin transducers with arbitrary boundary conditions. The transducers consist of an axially polarized piezoelectric solid cylinder sandwiched between two elastic solid cylinders. All three cylinders are of the same diameter. The length to diameter ratio is arbitrary. Complex piezoelectric and elastic coefficients are used to model internal losses. Solutions to the exact linearized governing equations for each cylinder include four series. Each term in each series is an exact solution to the governing equations. Bessel and trigonometric functions that form complete and orthogonal sets in the radial and axial directions, respectively, are used in the series. Asymmetric transducers and boundary conditions are modeled by using axially symmetric and anti-symmetric sets of functions. All interface and boundary conditions are satisfied in a weighted-average sense. The computed input electrical admittance, displacement, and stress in transducers are presented in tables and figures, and are in very good agreement with those obtained using atila-a finite element package for the analysis of sonar transducers. For all the transducers considered in the analysis, the maximum difference between the first three resonance frequencies calculated using the present method and atila is less than 0.03%.

  12. Software for Correcting the Dynamic Error of Force Transducers

    Directory of Open Access Journals (Sweden)

    Naoki Miyashita

    2014-07-01

    Full Text Available Software which corrects the dynamic error of force transducers in impact force measurements using their own output signal has been developed. The software corrects the output waveform of the transducers using the output waveform itself, estimates its uncertainty and displays the results. In the experiment, the dynamic error of three transducers of the same model are evaluated using the Levitation Mass Method (LMM, in which the impact forces applied to the transducers are accurately determined as the inertial force of the moving part of the aerostatic linear bearing. The parameters for correcting the dynamic error are determined from the results of one set of impact measurements of one transducer. Then, the validity of the obtained parameters is evaluated using the results of the other sets of measurements of all the three transducers. The uncertainties in the uncorrected force and those in the corrected force are also estimated. If manufacturers determine the correction parameters for each model using the proposed method, and provide the software with the parameters corresponding to each model, then users can obtain the waveform corrected against dynamic error and its uncertainty. The present status and the future prospects of the developed software are discussed in this paper.

  13. Microelectronics mounted on a piezoelectric transducer: method, simulations, and measurements.

    Science.gov (United States)

    Johansson, Jonny; Delsing, Jerker

    2006-01-01

    This paper describes the design of a highly integrated ultrasound sensor where the piezoelectric ceramic transducer is used as the carrier for the driver electronics. Intended as one part in a complete portable, battery operated ultrasound sensor system, focus has been to achieve small size and low power consumption. An optimized ASIC driver stage is mounted directly on the piezoelectric transducer and connected using wire bond technology. The absence of wiring between driver and transducer provides excellent pulse control possibilities and eliminates the need for broad band matching networks. Estimates of the sensor power consumption are made based on the capacitive behavior of the piezoelectric transducer. System behavior and power consumption are simulated using SPICE models of the ultrasound transducer together with transistor level modelling of the driver stage. Measurements and simulations are presented of system power consumption and echo energy in a pulse echo setup. It is shown that the power consumption varies with the excitation pulse width, which also affects the received ultrasound energy in a pulse echo setup. The measured power consumption for a 16 mm diameter 4.4 MHz piezoelectric transducer varies between 95 microW and 130 microW at a repetition frequency of 1 kHz. As a lower repetition frequency gives a linearly lower power consumption, very long battery operating times can be achieved. The measured results come very close to simulations as well as estimated ideal minimum power consumption.

  14. Home Automation System Based on Intelligent Transducer Enablers.

    Science.gov (United States)

    Suárez-Albela, Manuel; Fraga-Lamas, Paula; Fernández-Caramés, Tiago M; Dapena, Adriana; González-López, Miguel

    2016-09-28

    This paper presents a novel home automation system named HASITE (Home Automation System based on Intelligent Transducer Enablers), which has been specifically designed to identify and configure transducers easily and quickly. These features are especially useful in situations where many transducers are deployed, since their setup becomes a cumbersome task that consumes a significant amount of time and human resources. HASITE simplifies the deployment of a home automation system by using wireless networks and both self-configuration and self-registration protocols. Thanks to the application of these three elements, HASITE is able to add new transducers by just powering them up. According to the tests performed in different realistic scenarios, a transducer is ready to be used in less than 13 s. Moreover, all HASITE functionalities can be accessed through an API, which also allows for the integration of third-party systems. As an example, an Android application based on the API is presented. Remote users can use it to interact with transducers by just using a regular smartphone or a tablet.

  15. Characterization of noncontact piezoelectric transducer with conically shaped piezoelement

    Science.gov (United States)

    Williams, James H., Jr.; Ochi, Simeon C. U.

    1988-01-01

    The characterization of a dynamic surface displacement transducer (IQI Model 501) by a noncontact method is presented. The transducer is designed for ultrasonic as well as acoustic emission measurements and, according to the manufacturer, its characteristic features include a flat frequency response range which is from 50 to 1000 kHz and a quality factor Q of less than unity. The characterization is based on the behavior of the transducer as a receiver and involves exciting the transducer directly by transient pulse input stress signals of quasi-electrostatic origin and observing its response in a digital storage oscilloscope. Theoretical models for studying the response of the transducer to pulse input stress signals and for generating pulse stress signals are presented. The characteristic features of the transducer which include the central frequency f sub o, quality factor Q, and flat frequency response range are obtained by this noncontact characterization technique and they compare favorably with those obtained by a tone burst method which are also presented.

  16. Experimental Evaluation of Three Designs of Electrodynamic Flexural Transducers

    Science.gov (United States)

    Eriksson, Tobias J. R.; Laws, Michael; Kang, Lei; Fan, Yichao; Ramadas, Sivaram N.; Dixon, Steve

    2016-01-01

    Three designs for electrodynamic flexural transducers (EDFT) for air-coupled ultrasonics are presented and compared. An all-metal housing was used for robustness, which makes the designs more suitable for industrial applications. The housing is designed such that there is a thin metal plate at the front, with a fundamental flexural vibration mode at ∼50 kHz. By using a flexural resonance mode, good coupling to the load medium was achieved without the use of matching layers. The front radiating plate is actuated electrodynamically by a spiral coil inside the transducer, which produces an induced magnetic field when an AC current is applied to it. The transducers operate without the use of piezoelectric materials, which can simplify manufacturing and prolong the lifetime of the transducers, as well as open up possibilities for high-temperature applications. The results show that different designs perform best for the generation and reception of ultrasound. All three designs produced large acoustic pressure outputs, with a recorded sound pressure level (SPL) above 120 dB at a 40 cm distance from the highest output transducer. The sensitivity of the transducers was low, however, with single shot signal-to-noise ratio (SNR)≃15 dB in transmit–receive mode, with transmitter and receiver 40 cm apart. PMID:27571075

  17. Piezoelectric films for high frequency ultrasonic transducers in biomedical applications.

    Science.gov (United States)

    Zhou, Qifa; Lau, Sienting; Wu, Dawei; Shung, K Kirk

    2011-02-01

    Piezoelectric films have recently attracted considerable attention in the development of various sensor and actuator devices such as nonvolatile memories, tunable microwave circuits and ultrasound transducers. In this paper, an overview of the state of art in piezoelectric films for high frequency transducer applications is presented. Firstly, the basic principles of piezoelectric materials and design considerations for ultrasound transducers will be introduced. Following the review, the current status of the piezoelectric films and recent progress in the development of high frequency ultrasonic transducers will be discussed. Then details for preparation and structure of the materials derived from piezoelectric thick film technologies will be described. Both chemical and physical methods are included in the discussion, namely, the sol-gel approach, aerosol technology and hydrothermal method. The electric and piezoelectric properties of the piezoelectric films, which are very important for transducer applications, such as permittivity and electromechanical coupling factor, are also addressed. Finally, the recent developments in the high frequency transducers and arrays with piezoelectric ZnO and PZT thick film using MEMS technology are presented. In addition, current problems and further direction of the piezoelectric films for very high frequency ultrasound application (up to GHz) are also discussed.

  18. Piezoelectric transducer design for a miniaturized injectable acoustic transmitter

    Science.gov (United States)

    Li, H.; Jung, K. W.; Deng, Z. D.

    2015-11-01

    Implantable acoustic transmitters have been used in the last 20 years to track fish movement for fish survival and migration behavior studies. However, the relatively large weights and sizes of commercial transmitters limit the populations of studied fish. The surgical implantation procedures may also affect fish adversely and incur a significant amount of labor. Therefore, a smaller, lighter, and injectable transmitter was needed, and similar or better acoustic performance and service life over those provided by existing commercial transmitters was desired. To develop such a small transmitter, a number of technical challenges, including design optimization of the piezoelectric transducer, needed to be overcome. Our efforts to optimize the transducer focused on improving the average source level in the 180° range in which the signal was not blocked by the transmitter body. We found that a novel off-center tube transducer improved the average source level by 1.5 dB. An acoustic reflector attached to the back of the transducer also improved the source level by 1.3 dB. We found that too small a gap between the transducer and the component placed behind it resulted in distortion of the beam pattern. Lastly, a tuning inductor in series with the transducer was used to help optimize the source level. The findings and techniques developed in this work contributed to the successful development and implementation of a new injectable transmitter.

  19. Analytical calibration of linear transducer arrays for photoacoustic tomography

    Science.gov (United States)

    Oeri, Milan; Bost, Wolfgang; Fournelle, Marc

    2015-07-01

    Tomographic photoacoustic imaging (PAT) allows to overcome the anisotropic image resolution of conventional reflection mode imaging. In order to achieve high-resolution, tomographic images, precise information on the position of each detector element is required. PAT systems that acquire signals from rotating linear transducer arrays come with inevitable transducer misalignments. Up to now, transducer orientation (x/y-tilt) and radial distance uncertainty were measured experimentally or have not been considered. Uncalibrated, these systems suffer from characteristic artifacts yielding misinterpretations of anatomic structures. Herein, we derive the artifact mathematically and investigate an analytical calibration method that enables the calculation and compensation of important transducer positioning parameters: the rotational radius and in-plane tilt. We studied the approach theoretically and evaluated the performance of the developed algorithm both on numerical and experimental data. A PAT system based on a 5-MHz linear transducer array, a multichannel electronics platform with channel data access, a NIR-emitting laser system and a rotating samples is used to demonstrate the benefit of the transducer calibration method providing isotropic resolution of 160 μm.

  20. Focusing of ferroelectret air-coupled ultrasound transducers

    Science.gov (United States)

    Gaal, Mate; Bartusch, Jürgen; Dohse, Elmar; Schadow, Florian; Köppe, Enrico

    2016-02-01

    Air-coupled ultrasound has been applied increasingly as a non-destructive testing method for lightweight construction in recent years. It is particularly appropriate for composite materials being used in automotive and aviation industry. Air-coupled ultrasound transducers mostly consist of piezoelectric materials and matching layers. However, their fabrication is challenging and their signal-to-noise ratio often not sufficient for many testing requirements. To enhance the efficiency, air-coupled ultrasound transducers made of cellular polypropylene have been developed. Because of its small density and sound velocity, this piezoelectric ferroelectret matches the small acoustic impedance of air much better than matching layers applied in conventional transducers. In our contribution, we present two different methods of spherical focusing of ferroelectret transducers for the further enhancement of their performance in NDT applications. Measurements on carbon-fiber-reinforced polymer (CFRP) samples and on metal adhesive joints performed with commercially available focused air-coupled ultrasound transducers are compared to measurements executed with self-developed focused ferroelectret transducers.

  1. Home Automation System Based on Intelligent Transducer Enablers

    Directory of Open Access Journals (Sweden)

    Manuel Suárez-Albela

    2016-09-01

    Full Text Available This paper presents a novel home automation system named HASITE (Home Automation System based on Intelligent Transducer Enablers, which has been specifically designed to identify and configure transducers easily and quickly. These features are especially useful in situations where many transducers are deployed, since their setup becomes a cumbersome task that consumes a significant amount of time and human resources. HASITE simplifies the deployment of a home automation system by using wireless networks and both self-configuration and self-registration protocols. Thanks to the application of these three elements, HASITE is able to add new transducers by just powering them up. According to the tests performed in different realistic scenarios, a transducer is ready to be used in less than 13 s. Moreover, all HASITE functionalities can be accessed through an API, which also allows for the integration of third-party systems. As an example, an Android application based on the API is presented. Remote users can use it to interact with transducers by just using a regular smartphone or a tablet.

  2. Online monitoring of cracking in concrete structures using embedded piezoelectric transducers

    Science.gov (United States)

    Dumoulin, C.; Karaiskos, G.; Sener, J.-Y.; Deraemaeker, A.

    2014-10-01

    Online damage detection is of great interest in the field of concrete structures and, more generally, within the construction industry. Current economic requirements impose the reduction of the operating costs related to such inspection while the security and the reliability of structures must constantly be improved. In this paper, nondestructive testing is applied using piezoelectric transducers embedded in concrete structures. These transducers are especially adapted for online ultrasonic monitoring, due to their low cost, small size, and broad frequency band. These recent transducers are called smart aggregates. The technique of health monitoring developed in this study is based on a ultrasonic pulse velocity test with an embedded ultrasonic emitter-receiver pair (pitch-catch). The damage indicator focuses on the early wave arrival. The Belgian company MS3 takes an interest in evaluating the quality of the concrete around the anchorage system of highway security barriers after important shocks. The failure mechanism can be viewed as a combination of a bending and the failure of the anchorages. Accordingly, the monitoring technique has been applied both on a three-points bending test and several pull-out tests. The results indicate a very high sensitivity of the method, which is able to detect the crack initiation phase and follow the crack propagation over the entire duration of the test.

  3. Ultrasonic Transducers for Air and Underwater Communication.

    Science.gov (United States)

    Koosha, Abdolrahim

    Available from UMI in association with The British Library. The performance of a novel radiator capable of producing ultrasonic waves in air and liquids has been investigated. For commercial transducers when operating in air or liquids, impedance matching is the necessary condition for maximum transfer of energy to the medium (thus no standing waves are involved). However, for this radiator the formation of the mechanical standing waves on it is the key condition for directional radiation of energy into the surrounding environment. Under this condition the radiator exhibits a practical conversion of electrical energy into ultrasound. To further improve the performance of the radiator the wavelength coincidence condition must be satisfied. This condition implies that the wavelength of the bending vibration developed on the blade to be the same as that in the medium to which it is coupled. Consequently, an end-fire radiation pattern is obtained. The theory of this when applied to water and also for a double blade configuration are presented. The main component of the radiator consists of a cantilever blade on which a pair of piezoelectric (PZT) ceramic bars are fixed. These the so called excitation gauges, are fixed on both sides of a thin rectangular metal blade near the clamped end. When wavelength coincidence condition is fulfilled, the radiator transmits ultrasonic wave in a highly directional pattern. The direction of propagation of ultrasound is solely steered by frequency of the applied signal. System imperfections such as inter modal coupling when used underwater are considered. An analytical approach is developed to investigate the performance of the radiator for transmission of digital signals in air as well as in water. This method is used to evaluate the efficiency of the device as a suitable means for communication between divers or a diver and an underwater stationary station. Amplitude modulation of speech signals demonstrated the capabilities of a new

  4. Ultrasonic transducer chip assembly, ultrasound probe, ultrasonic imaging system and ultrasound assembly and probe manufacturing methods

    NARCIS (Netherlands)

    Weekamp, J.W.; Henneken, V.A.; Groenland, A.W.; Louwerse, M.C.

    2015-01-01

    Disclosed is an ultrasonic transducer assembly comprising an ultrasonic transducer chip (100) having a main surface comprising a plurality of ultrasound transducer elements (112) and a plurality of first contacts (120) for connecting to said ultrasound transducer elements; a contact chip (400) havin

  5. Design of a bullet beam pattern of a micro ultrasound transducer (Conference Presentation)

    Science.gov (United States)

    Roh, Yongrae; Lee, Seongmin

    2016-04-01

    Ultrasonic imaging transducer is often required to compose a beam pattern of a low sidelobe level and a small beam width over a long focal region to achieve good image resolution. Normal ultrasound transducers have many channels along its azimuth, which allows easy formation of the sound beam into a desired shape. However, micro-array transducers have no control of the beam pattern along their elevation. In this work, a new method is proposed to manipulate the beam pattern by using an acoustic multifocal lens and a shaded electrode on top of the piezoelectric layer. The shading technique split an initial uniform electrode into several segments and combined those segments to compose a desired beam pattern. For a given elevation width and frequency, the optimal pattern of the split electrodes was determined by means of the OptQuest-Nonlinear Program (OQ-NLP) algorithm to achieve the lowest sidelobe level. The requirement to achieve a small beam width with a long focal region was satisfied by employing an acoustic lens of three multiple focuses. Optimal geometry of the multifocal lens such as the radius of curvature and aperture diameter for each focal point was also determined by the OQ-NLP algorithm. For the optimization, a new index was devised to evaluate the on-axis response: focal region ratio = focal region / minimum beam width. The larger was the focal region ratio, the better was the beam pattern. Validity of the design has been verified through fabricating and characterizing an experimental prototype of the transducer.

  6. Ultrasonic flowmeters: temperature gradients and transducer geometry effects.

    Science.gov (United States)

    Willatzen, M

    2003-03-01

    Ultrasonic flowmeter performance is addressed for the case of cylindrically shaped flowmeters employing two reciprocal ultrasonic transducers A and B so as to measure time-of-flight differences between signals transmitted from transducer A towards B followed by an equivalent signal transmitted from transducer B towards A. In the case where a liquid flows through the flowmeter's measuring section ("spoolpiece"), the arrival times of the two signals differ by an amount related to the flow passing between the two transducers. Firstly, a detailed study of flow measurement errors with mean flow in the laminar flow regime is carried out as a function of the mode index and the transducer diameter/cylinder diameter ratio in the case where no temperature gradients are present in the flowmeter sensor. It is shown that all modes except the fundamental mode overestimate the mean flow by a factor of 33.33% while excitation of the fundamental mode solely give error-free measurements. The immediate consequences are that the flowmeter error decreases as the transducer diameter/cylinder diameter ratio approaches 1 from 0 reflecting the fact that the excitation level of the fundamental mode increases from almost 0 to 1 as this ratio approaches 1 from 0. Secondly, the effect on flowmeter performance due to flow-induced temperature gradients is examined. It is shown that the presence of temperature gradients leads to flowmeter errors at the higher-flow values even in the case where the fundamental mode is the only mode excited. It is also deduced that flowmeter errors in general depend on the distance between transducers A and B whether temperature gradients exist or not. This conclusion is not reflected in the usual definition of flowmeter errors given by the so-called mode-dependent deviation of measurement introduced in earlier works.

  7. Transducer-binding and transducer-mutations modulate photoactive-site-deprotonation in sensory rhodopsin I.

    Science.gov (United States)

    Jung, K H; Spudich, E N; Dag, P; Spudich, J L

    1999-10-05

    Sensory rhodopsin I (SRI) is a seven-transmembrane helix retinylidene protein that mediates color-sensitive phototaxis responses through its bound transducer HtrI in the archaeon Halobacterium salinarum. Deprotonation of the Schiff base attachment site of the chromophore accompanies formation of the SRI signaling state, S(373). We measured the rate of laser flash-induced S(373) formation in the presence and absence of HtrI, and the effects of mutations in SRI or HtrI on the kinetics of this process. In the absence of HtrI, deprotonation occurs rapidly (halftime 10 micros) if the proton acceptor Asp76 is ionized (pK(a) = approximately 7), and only very slowly (halftime > 10 ms) when Asp76 is protonated. Transducer-binding, although it increases the pK(a) of Asp76 so that it is protonated throughout the range of pH studied, results in a first order, pH-independent rate of S(373) formation of approximately 300 micros. Therefore, the complexation of HtrI facilitates the proton-transfer reaction, increasing the rate approximately 50-fold at pH6. Arrhenius analysis shows that HtrI-binding accelerates the reaction primarily by an entropic effect, suggesting HtrI constrains the SRI molecule in the complex. Function-perturbing mutations in SRI and HtrI also alter the rate of S(373) formation and the lambda(max) of the parent state as assessed by laser flash-induced kinetic difference spectroscopy, and shifts to longer wavelength are correlated with slower deprotonation. The data indicate that HtrI affects electrostatic interactions of the protonated Schiff base and not only receives the signal from SRI but also optimizes the photochemical reaction process for SRI signaling.

  8. 1-3 Piezocomposite transducers for AUV applications

    Science.gov (United States)

    Pazol, Brian; Lannaman, Ken; Doust, Barry

    2001-05-01

    Sonar systems on board AUVs present interesting challenges to the transducer designer because of their small size, low weight requirements, and limited available power. 1-3 piezocomposite transducers offer many performance characteristics which make them ideal for deployment in AUVs. Piezocomposite transducers are light weight, have broad bandwidth, have high efficiency, and can be conformed to fit the curvature of the vehicle. The broad bandwidths and low sidelobes made possible by piezocomposites result in sharper images with less distortion. The piezocomposite material is mechanically robust and can survive the rigors of normal operations as well as AUV deployment and retrieval. In addition, the conformal configuration substantially reduces hydrodynamic drag. As a conformal array, there is nothing to get knocked off during deployment and retrieval operations, or entangled with natural or man-made objects suspended in the water column. This contributes directly to improving the operational endurance of the AUV system, thereby enhancing overall system utility. MSI has produced and tested a variety of piezocomposite transducers for use in obstacle avoidance, mine hunting, and acoustic communications. An overview of piezocomposites and recent results of piezocomposite transducers will be presented.

  9. Delimitation of the lung region with distributed ultrasound transducers

    Science.gov (United States)

    Cardona Cárdenas, Diego Armando; Furuie, Sérgio Shiguemi

    2016-04-01

    One technique used to infer and monitor patient's respiratory conditions is the electrical impedance tomography (EIT). This provides images with information about lung function. The EIT image contrast is dependent on the variation of electrical impedance, therefore, this image does not provide anatomical details in border regions of several organs. To contribute to a clinical solution, we propose a new method to delimit regions of interest such as the pulmonary region and to improve the reconstruction quality of the EIT. Using a Matlab Toolbox k-wave, the ultrasound propagation phenomenon in homogeneous medium without patient (Reference) and with thoracic models were simulated, separately via a set of several ultrasound transducers distributed around the chest. After pulse emission by a transducer (TR), all received signals were compared considering the two sets of signals. If the energy relation between parts of the signals does not exceed an empirical threshold (30% in this study), a partial mask is generated between the transmitter and the receptor. This process was repeated until all 128 transducers are considered as TR-emitters. The 128 transducers (150kHz) are uniformly distributed. The evaluation was made by visually comparing the resulting images with the respective simulated object. A simple approach was presented to delimit high contrast organs with ultrasound transducers distributed around the patient. This approach allows other lower contrast objects to become invisible by varying the threshold limit. The investigation, based on numerical simulations of ultrasonic propagation, has shown promising results in the delimitation of the pulmonary region.

  10. Wideband Tonpilz Transducer with a Cavity Inside a Head Mass

    Science.gov (United States)

    Saosometh Chhith,; Yongrae Roh,

    2010-07-01

    A multimode Tonpilz transducer is well-known for providing a wider bandwidth than a single-mode transducer. In this paper, a new structure for the head mass of a multimode Tonpilz transducer was designed to further widen the bandwidth. The mechanical quality factor of a Tonpilz transducer is proportional to the weight of its head mass. In that sense, making the cavity inside the head mass will surely lead to a much lighter head mass, which can lead to a lower mechanical quality factor, thus a wider bandwidth. Through finite element analyses, the effects of the void head mass structure on the transducer performance were analyzed, and the dimension of the cavity to achieve the widest bandwidth was determined within given structural variation ranges. The variation ranges were selected as those in which the coefficient of determination in regression analyses was larger than 0.95 over all the ranges. The structure of a tail mass was also designed using the same method to match the new head mass.

  11. A hybrid transducer to magnetically and ultrasonically evaluate magnetic fluids.

    Science.gov (United States)

    Bruno, Alexandre Colello; Pavan, Théo Z; Baffa, Oswaldo; Carneiro, Antonio Adilton Oliveira

    2013-09-01

    Ultrasound, magnetic fields, and optical techniques have been explored for clinical diagnosis and therapy. However, these techniques have limitations. In this study, we constructed and characterized a transducer to magnetically and ultrasonically investigate samples labeled with magnetic particles. The transducer is a hybrid system consisting of an ac biosusceptometer (ACB) and an ultrasonic transducer. The basic operation principle consisted of measuring the magnetization and microvibrations of ferromagnetic particles (37 and 70 μm) mixed in yogurt and excited by an external alternating magnetic field generated by the ACB's excitation coils. The vibration of the ferromagnetic particles was measured in phantoms using a Doppler ultrasonic transducer; we verified the sensitivity to detecting the vibrations at low concentrations of ferromagnetic material (~1%). The responses of the susceptometer and Doppler ultrasound linearly depended on the voltage level applied to the magnetizing coils at low ferromagnetic particle concentrations (⩽ 5%). We also conducted a repeatability test on the prototype, which indicated a deviation of 0.94% and 0.25% in the Doppler and susceptometric measurements, respectively. We can conclude that the hybrid transducer technique has potential clinical applications.

  12. A highly sensitive fiber Bragg grating diaphragm pressure transducer

    Science.gov (United States)

    Allwood, Gary; Wild, Graham; Lubansky, Alex; Hinckley, Steven

    2015-10-01

    In this work, a novel diaphragm based pressure transducer with high sensitivity is described, including the physical design structure, in-depth analysis of optical response to changes in pressure, and a discussion of practical implementation and limitations. A flat circular rubber membrane bonded to a cylinder forms the body of the transducer. A fiber Bragg grating bonded to the center of the diaphragm structure enables the fractional change in pressure to be determined by analyzing the change in Bragg wavelength of the reflected spectra. Extensive evaluation of the physical properties and optical characteristics of the transducer has been performed through experimentation, and modeling using small deformation theory. The results show the transducer has a sensitivity of 0.116 nm/kPa, across a range of 15 kPa. Ultra-low cost interrogation of the optical signal was achieved through the use of an optically mismatched Bragg grating acting as an edge filter to convert the spectral change into an intensity change. A numerical model of the intensity based interrogation was implemented in order to validate the experimental results. Utilizing this interrogation technique and housing both the sensing and reference Bragg gratings within the main body of the transducer means it is effectively temperature insensitive and easily connected to electronic systems.

  13. Three-Dimensional Synthetic Aperture Focusing Using a Rocking Convex Array Transducer

    DEFF Research Database (Denmark)

    Andresen, Henrik; Nikolov, Svetoslav; Pedersen, Mads Møller;

    2010-01-01

    Volumetric imaging can be performed using 1-D arrays in combination with mechanical motion. Outside the elevation focus of the array, the resolution and contrast quickly degrade compared with the lateral plane, because of the fixed transducer focus. This paper shows the feasibility of using...... synthetic aperture focusing for enhancing the elevation focus for a convex rocking array. The method uses a virtual source (VS) for defocused multi-element transmit, and another VS in the elevation focus point. This allows a direct time-of-flight to be calculated for a given 3-D point. To avoid artifacts...

  14. Ultrasonic inspection of rocket fuel model using laminated transducer and multi-channel step pulser

    Science.gov (United States)

    Mihara, T.; Hamajima, T.; Tashiro, H.; Sato, A.

    2013-01-01

    For the ultrasonic inspection for the packing of solid fuel in a rocket booster, an industrial inspection is difficult. Because the signal to noise ratio in ultrasonic inspection of rocket fuel become worse due to the large attenuation even using lower frequency ultrasound. For the improvement of this problem, we tried to applied the two techniques in ultrasonic inspection, one was the step function pulser system with the super wideband frequency properties and the other was the laminated element transducer. By combining these two techniques, we developed the new ultrasonic measurement system and demonstrated the advantages in ultrasonic inspection of rocket fuel model specimen.

  15. Reducing the Effect of Transducer Mount Induced Noise on Aeroacoustic Wind Tunnel Testing Data with a New Transducer Mount Design

    Science.gov (United States)

    Herron, A. J.; Reed, D. K.; Nance, D. K.

    2015-01-01

    Characterization of launch vehicle unsteady aerodynamics is a field best studied through experimentation, which is often carried out in the form of large scale wind tunnel testing. Measurement of the fluctuating pressures induced by the boundary layer noise is customarily made with miniature pressure transducers installed into a model of the vehicle of interest. Literature shows that noise level increases between two to five decibels (dB referenced to 20 micropascal) can be induced when the transducer surface is not mounted perfectly flush with the model outer surface. To reduce this artificially induced noise, special transducer holders have been used for aeroacoustic wind tunnel testing by NASA. This holder is a sleeve into which the transducer fits, with a cap that allows it to be mounted in a recessed hole in the model. A single hole in the holder allows the transport of the tunnel medium so the transducer can discriminate the fluctuating pressure due to the turbulent boundary layer noise. The holder is first dry fitted into the model and any difference in height between the holder and the model surface can be sanded flush. The holder is then removed from the model, the transducer glued inside the holder, and the holder replaced in the model, secured also with glue, thus eliminating the problem of noise level increases due to lack of flushness. In order to work with this holder design, special transducers have been ordered with their standard screen removed and the diaphragm moved as close to the top of the casing as possible to minimize any cavity volume. Although this greatly reduces induced noise due to the transducers being out of flush, the holders can also induce a cavity resonance that is usually at a very high frequency. This noise is termed transducer mount induced noise (XMIN). The peak of the mode can vary with the cavity depth, boundary layer noise that can excite the mode, tunnel flow medium, and the build of the transducers. Because the boundary

  16. Energy harvesting with a slotted-cymbal transducer

    Institute of Scientific and Technical Information of China (English)

    Jiang-bo YUAN; Xiao-biao SHAN; Tao XIE; Wei-shan CHEN

    2009-01-01

    A cymbal transducer is made up of a piezoceramic disk sandwiched between two dome-shaped metal endcaps. High circumferential stresses caused by flexural motion of the metal endcaps can induce the loss of mechanical input energy. Finite element analysis shows that the radial slots fabricated in metal endcaps can release the circumferential stresses, and reduce the loss of mechanical input energy that could be converted into electrical energy. In this letter, the performance of a slotted-cymbal transducer in energy harvesting was tested. The results show that the output voltage and power of the cymbal are improved. A maximum output power of around 16 mW could be harvested from a cymbal with 18 cone radial slots across a 500kΩ resistive load, which is approximately 0.6 times more than that of the original cymbal transducer.

  17. A novel serrated columnar phased array ultrasonic transducer

    Science.gov (United States)

    Zou, Cheng; Sun, Zhenguo; Cai, Dong; Song, Hongwei; Chen, Qiang

    2016-02-01

    Traditionally, wedges are required to generate transverse waves in a solid specimen and mechanical rotation device is needed for interrogation of a specimen with a hollow bore, such as high speed railway locomotive axles, turbine rotors, etc. In order to eliminate the mechanical rotation process, a novel array pattern of phased array ultrasonic transducers named as serrated columnar phased array ultrasonic transducer (SCPAUT) is designed. The elementary transducers are planar rectangular, located on the outside surface of a cylinder. This layout is aimed to generate electrically rotating transverse waveforms so as to inspect the longitudinal cracks on the outside surface of a specimen which has a hollow bore at the center, such as the high speed railway locomotive axles. The general geometry of the SCPAUT and the inspection system are illustrated. A FEM model and mockup experiment has been carried out. The experiment results are in good agreement with the FEM simulation results.

  18. The Use of Phononic Crystals to Design Piezoelectric Power Transducers

    Directory of Open Access Journals (Sweden)

    Silvia Ronda

    2017-03-01

    Full Text Available It was recently proposed that the lateral resonances around the working resonance band of ultrasonic piezoelectric sandwich transducers can be stopped by a periodic array of circular holes drilled along the main propagation direction (a phononic crystal. In this work, the performance of different transducer designs made with this procedure is tested using laser vibrometry, electric impedance tests and finite element models (FEM. It is shown that in terms of mechanical vibration amplitude and acoustic efficiency, the best design for physiotherapy applications is when both, the piezoceramic and an aluminum capsule are phononic structures. The procedure described here can be applied to the design of power ultrasonic devices, physiotherapy transducers and other external medical power ultrasound applications where piston-like vibration in a narrow band is required.

  19. Design, production and testing of PMN-PT electrostrictive transducers.

    Science.gov (United States)

    Coutte, J; Dubus, B; Debus, J C; Granger, C; Jones, D

    2002-05-01

    Lead magnesium niobate ceramics (PMN) are promising materials for application in the field of high power transducers. The advantage of PMN materials are the large strains generated under moderate electric field and the low hysteresis. The electrostrictive effect is non-linear, the corresponding physical constants depend on temperature and frequency and a DC electrical bias is required. These difficulties must be considered at the design stage. A finite element model has been developed and validated in the ATILA code for non-linear static and time-domain analyses. These numerical modelings are used to design and test two Langevin-type electrostrictive transducers. The first transducer is made of PMN-PT-La (90-10-1%) ceramics (TRS Ceramics), the second one of ESCI ceramics (Morgan Matroc). For given static mechanical prestresses, resonance frequencies and effective coupling coefficients are measured at different DC electric fields and temperatures.

  20. Inter Digital Transducer Modelling through Mason Equivalent Circuit Model

    DEFF Research Database (Denmark)

    Mishra, Dipti; Singh, Abhishek; Hussain, Dil muhammed Akbar

    2016-01-01

    by Simulation program with Integrated Circuit Emphasis (HSPICE), a well-liked electronic path simulator. The acoustic wave devices are not suitable to simulation through circuit simulator.In this paper, an electrical model of Mason’s Equivalent electricalcircuit for an inter-digital transducer (IDT......The frequency reliance of inter-digital transducer is analyzed with the help of MASON’s Equivalent circuit which is based on Smith’s Equivalent circuit which is further based on Foster’sNetwork. An inter-digital transducer has been demonstratedas a RLC network. The circuit is simulated......) is projected which is well-suitedwith a broadlycast-offuniversalresolution circuit simulator SPICE built-in out with the proficiency to simulatethenegative capacitances and inductances. The investigationis done to prove the straightforwardness of establishing the frequency and time domain physical...

  1. Phased annular array transducers for ultrasonic guided wave applications

    Science.gov (United States)

    Yan, Fei; Borigo, Cody; Liang, Yue; Koduru, Jaya P.; Rose, Joseph L.

    2011-04-01

    Mode and frequency control always plays an important role in ultrasonic guided wave applications. In this paper, theoretical understanding of guided wave excitations of axisymmetric sources on plate structures is established. It is shown that a wave number spectrum can be used to investigate the guided wave excitations of an axisymmetric source. The wave number spectrum is calculated from a Hankel transform of the axial source loading profile. On the basis of the theoretical understanding, phased annular array transducers are developed as a powerful tool for guided wave mode and frequency control. By applying appropriate time delays to phase the multiple elements of an annular array transducer, guided wave mode and frequency tuning can be achieved fully electronically. The phased annular array transducers have been successfully used for various applications. Example applications presented in this paper include phased annular arrays for guided wave beamforming and a novel ultrasonic vibration modal analysis technique for damage detection.

  2. Some design considerations for small piezo-electrical ceramic transducers

    Science.gov (United States)

    Rijnja, H. A. J.

    1989-07-01

    The design parameters and the characteristics of small omnidirectional transducers, to be applied under water as projectors in the frequency range of about 1 kHz to 100 kHz and as hydrophones from very low frequencies up to again 100kHz are described. The transducers are constructed with piezoelectrical ceramic materials in the shape of hollow spheres, end capped tubes or piston (Tonpilz) elements. The highest source levels are obtained with spherical transducers as single omnidirectional sound sources. If larger arrays of sources are applied the array should be composed of single ended Tonpilz elements. The most sensitive receivers (hydrophones) are obtained with tangentially polarized end-capped tubes.

  3. Finite element analysis of piezoelectric underwater transducers for acoustic characteristics

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jae Hwan [Inha University, Incheon (Korea, Republic of); Kim, Heung Soo [Catholic University, Daegu (Korea, Republic of)

    2009-02-15

    This paper presents a simulation technique for analyzing acoustic characteristics of piezoelectric underwater transducers. A finite element method is adopted for modeling piezoelectric coupled problems including material damping and fluid-structure interaction problems by taking system matrices in complex form. For the finite element modeling of unbounded acoustic fluid, infinite wave envelope element (IWEE) is adopted to take into account the infinite domain. An in-house finite element program is developed and technical issues for implementing the program are explained. Using the simulation program, acoustic characteristics of tonpilz transducer are analyzed in terms of modal analysis, radiated pressure distribution, pressure spectrum, transmitting-voltage response and impedance analysis along with experimental comparison. The developed simulation technique can be used for designing ultrasonic transducers in the areas of nondestructive evaluation, underwater acoustics and bioengineering

  4. Actuators, transducers and motors based on giant magnetostrictive materials

    Energy Technology Data Exchange (ETDEWEB)

    Claeyssen, F.; Lhermet, N.; Le Letty, R. [Cedrat Recherche, Meylan (France); Bouchilloux, P. [Magsoft Corporation, 1223 People`s Avenue, New York 12180 (United States)

    1997-08-01

    Rare earth-iron magnetostrictive alloys, especially Terfenol-D, feature ``giant`` magnetostrains: static strains of 1000-2000 ppm and dynamic strains of 3500 ppm are reported. These strains permit building various actuating devices (actuators, transducers, motors) both at macro and micro scale. The object of the paper is to recall adapted design methods, especially finite element methods such as ATILA, and to review these different kinds of devices studied at Cedrat Recherche, providing both up-dated experimental and numerical results. The presented devices will include several large displacement longitudinal and shear actuators biased using permanent magnets and used either as characterisation devices or as electromechanical actuators (for active damping, for sonar transducers..), a 1 kHz 4 kW Tonpilz-type sonar transducer called the tripode, a 2 N m torque rotating multi-mode motor, a torsion based drift free micro actuator and a wireless linear micromotor. (orig.)

  5. INFLUENCE OF PIEZOELECTRIC TRANSDUCER TO GLASS FIBER REINFORCED COMPOSITE STIFFNESS

    Directory of Open Access Journals (Sweden)

    Witold Rządkowski

    2015-08-01

    Full Text Available The main goal was to determine if transducers based on piezoelectric materials are suitable for strain calculations in thin GFRP specimens. Numerous experimental studies, both physical and numerical, performed by the authors, have shown that there is a huge influence of bonded piezoelectric transducer on the overall stiffness of the measured object. The paper presents tensile test performed on strength machine with Digital Image Correlation strain and deflection observations. Test were compared with FEM models for detailed investigation. The main conclusion is piezoelectric transducers has huge influence on local stiffness of measured object. That is critical especially when they are used as strain sensors, when presence of sensor is influencing to measured results.

  6. Novice performance of ultrasound-guided needle advancement: standard 38-mm transducer vs 25-mm hockey stick transducer.

    Science.gov (United States)

    Davies, T; Townsley, P; Jlala, H; Dowling, M; Bedforth, N; Hardman, J G; McCahon, R A

    2012-08-01

    The optimal method to develop expertise in ultrasound-guided regional anaesthesia is unknown. Studies of laryngoscopic expertise in novices demonstrate that the choice of laryngoscope affects performance. In this study, we aimed to compare the effect of two different linear array transducers (38-mm standard vs 25-mm hockey stick) on novice performance of ultrasound-guided needle advancement. Following randomisation, participants watched a video model of expert performance of ultrasound-guided needle advancement. Recruits performed the modelled task on a turkey breast model. The median (IQR [range]) composite error score was statistically significantly larger for participants in the hockey stick transducer group compared with the standard transducer group; 10.0 (7.3-14.3 [2.5-29.0]) vs 7.5 (4.5-10.0 [2.0-28.0]) respectively, (p = 0.01). This study has demonstrated that performance of ultrasound-guided needle advancement by novice operators after simple video instruction is better (as assessed using a composite error score) with a standard 38-mm transducer than with a 25-mm hockey stick transducer. Anaesthesia © 2012 The Association of Anaesthetists of Great Britain and Ireland.

  7. High intensity ultrasound transducer used in gene transfection

    Science.gov (United States)

    Morrison, Kyle P.; Keilman, George W.; Noble, Misty L.; Brayman, Andrew A.; Miao, Carol H.

    2012-11-01

    This paper describes a novel therapeutic high intensity non-focused ultrasound (HIU) transducer designed with uniform pressure distribution to aid in accelerated gene transfer in large animal liver tissues in vivo. The underlying HIU transducer was used to initiate homogeneous cavitation throughout the tissue while delivering up to 2.7 MPa at 1.1 MHz across its radiating surface. The HIU transducer was built into a 6 cm diameter x 1.3 cm tall housing ergonomically designed to avoid collateral damage to the surrounding anatomy during dynamic motion. The ultrasound (US) radiation was applied in a 'paintbrush-like' manner to the surface of the liver. The layers and geometry of the transducer were carefully selected to maximize the active diameter (5.74 cm), maximize the electrical to acoustic conversion efficiency (85%) to achieve 2.7 MPa of peak negative pressure, maximize the frequency operating band at the fundamental resonance to within a power transfer delta of 1 dB, and reduce the pressure delta to within 2 dB across the radiating surface. For maximum peak voltage into the transducer, a high performance piezoceramic was chosen and a DC bias circuit was built integral to the system. An apodized two element annular pattern was made from a single piezoceramic element, resulting in significant pressure uniformity enhancement. In addition to using apodization for pressure uniformity, a proprietary multi-layered structure was used to improve efficiency while sustaining an operating band from 900 kHz to 1.3 MHz. The resultant operating band allowed for dithering techniques using frequency modulation. The underlying HIU transducer for use in large animals enhances gene expression up to 6300-fold.

  8. The planar silicon-based microelectronic technology for electrochemical transducers

    Science.gov (United States)

    Novikov, A. V.; Egorchikov, A. E.; Dolgov, A. N.; Gornev, E. S.; Popov, V. G.; Egorov, I. V.; Krishtop, V. G.

    2016-12-01

    We have developed the new technology for production of sensitive modules for electrochemical sensors of pressure and acceleration. The technology is applicable for mass production and scalable for high-volume production. In this work we demonstrate the new sensing module for electrochemical motion sensors, and its possibility of applying in geophones. We fabricated prototypes of electrochemical planar transducer chips, produced a laboratory prototype of a geophone based on our planar transducer chip, and tested them. This paper presents the preliminary results of the tests.

  9. Sensory TRP channels: the key transducers of nociception and pain.

    Science.gov (United States)

    Mickle, Aaron D; Shepherd, Andrew J; Mohapatra, Durga P

    2015-01-01

    Peripheral detection of nociceptive and painful stimuli by sensory neurons involves a complex repertoire of molecular detectors and/or transducers on distinct subsets of nerve fibers. The majority of such molecular detectors/transducers belong to the transient receptor potential (TRP) family of cation channels, which comprise both specific receptors for distinct nociceptive stimuli, as well as for multiple stimuli. This chapter discusses the classification, distribution, and functional properties of individual TRP channel types that have been implicated in various nociceptive and/or painful conditions.

  10. Simulating Capacitive Micromachined Ultrasonic Transducers (CMUTs) using Field II

    DEFF Research Database (Denmark)

    Bæk, David; Oralkan, Omer; Kupnik, Mario;

    2010-01-01

    Field II has been a recognized simulation tool for piezoceramic medical transducer arrays for more than a decade. The program has its strength in doing fast computations of the spatial impulse response (SIR) from array elements by dividing the elements into smaller mathematical elements (ME)s from...... which it calculates the SIR responses. The program features predefined models for classical transducer geometries, but currently none for the fast advancing CMUTs. This work addresses the assumptions required for modeling CMUTs with Field II. It is shown that rectangular array elements, populated...

  11. Switchable adhesion for wafer-handling based on dielectric elastomer stack transducers

    Science.gov (United States)

    Grotepaß, T.; Butz, J.; Förster-Zügel, F.; Schlaak, H. F.

    2016-04-01

    Vacuum grippers are often used for the handling of wafers and small devices. In order to evacuate the gripper, a gas flow is created that can harm the micro structures on the wafer. A promising alternative to vacuum grippers could be adhesive grippers with switchable adhesion. There have been some publications of gecko-inspired adhesive devices. Most of these former works consist of a structured surface which adheres to the object manipulated and an actuator for switching the adhesion. Until now different actuator principles have been investigated, like smart memory alloys and pneumatics. In this work for the first time dielectric elastomer stack transducers (DEST) are combined with a structured surface. DESTs are a promising new transducer technology with many applications in different industry sectors like medical devices, human-machine-interaction and soft robotics. Stacked dielectric elastomer transducers show thickness contraction originating from the electromechanical pressure of two compliant electrodes compressing an elastomeric dielectric when a voltage is applied. Since DESTs and the adhesive surfaces previously described are made of elastomers, it is self-evident to combine both systems in one device. The DESTs are fabricated by a spin coating process. If the flat surface of the spinning carrier is substituted for example by a perforated one, the structured elastomer surface and the DEST can be fabricated in one process. By electrical actuation the DEST contracts and laterally expands which causes the gecko-like cilia to adhere on the object to manipulate. This work describes the assembly and the experimental results of such a device using switchable adhesion. It is intended to be used for the handling of glass wafers.

  12. Analysis of eigenfrequencies in piezoelectric transducers using the finite element method

    DEFF Research Database (Denmark)

    Jensen, Henrik

    1988-01-01

    It is noted that the finite-element method is a valuable supplement to the traditional methods for design of novel transducer types because it can determine the vibrational pattern of piezoelectric transducers and is applicable to any geometry. Computer programs for analysis of axisymmetric...... transducers, which include the complete set of piezoelectric equations, have been included. They can find eigenfrequencies for undamped transducers and perform forced-response analysis for transducers with internal and radiation damping. The superelement technique is used to model the transducer backing...

  13. Investigation of capacitively coupled ultrasonic transducer system for nondestructive evaluation.

    Science.gov (United States)

    Zhong, Cheng Huan; Wilcox, Paul D; Croxford, Anthony J

    2013-12-01

    Capacitive coupling offers a simple solution to wirelessly probe ultrasonic transducers. This paper investigates the theory, feasibility, and optimization of such a capacitively coupled transducer system (CCTS) in the context of nondestructive evaluation (NDE) applications. The noncontact interface relies on an electric field formed between four metal plates-two plates are physically connected to the electrodes of a transducer, the other two are in a separate probing unit connected to the transmit/receive channel of the instrumentation. The complete system is modeled as an electric network with the measured impedance of a bonded piezoelectric ceramic disc representing a transducer attached to an arbitrary solid substrate. A transmission line model is developed which is a function of the physical parameters of the capacitively coupled system, such as the permittivity of the material between the plates, the size of the metal plates, and their relative positions. This model provides immediate prediction of electric input impedance, pulse-echo response, and the effect of plate misalignment. The model has been validated experimentally and has enabled optimization of the various parameters. It is shown that placing a tuning inductor and series resistor on the transmitting side of the circuit can significantly improve the system performance in terms of the signal-to-crosstalk ratio. Practically, bulk-wave CCTSs have been built and demonstrated for underwater and through-composite testing. It has been found that electrical conduction in the media between the plates limits their applications.

  14. Inductively coupled transducer system for damage detection in composites

    Science.gov (United States)

    Zhong, C. H.; Croxford, A. J.; Wilcox, P. D.

    2012-04-01

    The laminated construction of composite offers the possibility of permanently embedding sensors into structure, for example, ultrasonic transducers which can be used for NDE applications. An attractive and simple solution for probing embedded sensors wirelessly is via inductive coupling. However, before this can be achieved it is necessary to have a full understanding and proper design strategy for the inductively coupled system. This paper presents the developments of both system design procedure and a computer program for one dimensional inductively coupled transducer system mounted on a solid substrate. The design strategy in this paper mainly focuses on issues of localization of transducers, and optimizing the signal to noise level. Starting from a three coil equivalent circuit, this paper also explains how the measured impedance of a bonded piezoelectric disc is implemented into the system model representing a transducer bonded to an arbitrary solid substrate. The computer programme using this model provides immediate predictions of electrical input impedance, acoustic response and pulse-echo response. A series of experiments and calculations have been performed in order to validate the model. This has enabled the degree of accuracy required for various parameters within the model, such as mutual inductance between the coils and self-inductance of coils, to be assessed. Once validated, the model can be used as a tool to predict the effect of physical parameters, such as distance, lateral misalignment between the coils, and the coil geometry on the performance of an inductively coupled system.

  15. High Temperature Ultrasonic Transducers : Material Selection and Testing

    Science.gov (United States)

    Bar-Cohen, Yoseph; Bruno, Alessandro

    2012-01-01

    The task of my two-months internship was to test different materials to be used to build an high temperature transducer, to develop some prototypes and to test their performance, to assess the reliability of commercial product rated for such a temperature, as well as to collaborate in developing the signal processing code to measure the condensed water levels.

  16. A Novel Rotary Piezoelectric Motor Using First Bending Hybrid Transducers

    Directory of Open Access Journals (Sweden)

    Yingxiang Liu

    2015-08-01

    Full Text Available We report a novel rotary piezoelectric motor using bending transducers in this work. Three transducers are used to drive a disk-shaped rotor together by the elliptical movements of their driving tips; these motions are produced by the hybrid of two first bending vibration modes. The proposed piezoelectric transducer has a simple structure as it only contains an aluminum alloy beam and four pieces of PZT plates. Symmetrical structure is the only necessary condition in the design process as it will ensure the resonance frequencies of the two orthogonal first bending modes are equal. Transducers with first bending resonance frequency of about 53 kHz were fabricated and assembled into a rotary motor. The proposed motor exhibits good performance on speed and torque control. Under a working frequency of 53.2 kHz, the maximum no-load speed and the maximum torque of the prototype are tested to be 53.3 rpm and of 27 mN·m.

  17. Transverse Mode Multi-Resonant Single Crystal Transducer

    Science.gov (United States)

    Snook, Kevin A. (Inventor); Liang, Yu (Inventor); Luo, Jun (Inventor); Hackenberger, Wesley S. (Inventor); Sahul, Raffi (Inventor)

    2015-01-01

    A transducer is disclosed that includes a multiply resonant composite, the composite having a resonator bar of a piezoelectric single crystal configured in a d(sub 32) transverse length-extensional resonance mode having a crystallographic orientation set such that the thickness axis is in the (110) family and resonance direction is the (001) family.

  18. A distributed transducer system for functional electrical stimulation

    DEFF Research Database (Denmark)

    Gudnason, Gunnar; Nielsen, Jannik Hammel; Bruun, Erik

    2001-01-01

    Implanted transducers for functional electrical stimulation (FES) powered by inductive links are subject to conflicting requirements arising from low link efficiency, a low power budget and the need for protection of the weak signals against strong RF electromagnetic fields. We propose a solution...

  19. A capacitive ultrasonic transducer based on parametric resonance

    Science.gov (United States)

    Surappa, Sushruta; Satir, Sarp; Levent Degertekin, F.

    2017-07-01

    A capacitive ultrasonic transducer based on a parametric resonator structure is described and experimentally demonstrated. The transducer structure, which we call capacitive parametric ultrasonic transducer (CPUT), uses a parallel plate capacitor with a movable membrane as part of a degenerate parametric series RLC resonator circuit with a resonance frequency of fo. When the capacitor plate is driven with an incident harmonic ultrasonic wave at the pump frequency of 2fo with sufficient amplitude, the RLC circuit becomes unstable and ultrasonic energy can be efficiently converted to an electrical signal at fo frequency in the RLC circuit. An important characteristic of the CPUT is that unlike other electrostatic transducers, it does not require DC bias or permanent charging to be used as a receiver. We describe the operation of the CPUT using an analytical model and numerical simulations, which shows drive amplitude dependent operation regimes including parametric resonance when a certain threshold is exceeded. We verify these predictions by experiments with a micromachined membrane based capacitor structure in immersion where ultrasonic waves incident at 4.28 MHz parametrically drive a signal with significant amplitude in the 2.14 MHz RLC circuit. With its unique features, the CPUT can be particularly advantageous for applications such as wireless power transfer for biomedical implants and acoustic sensing.

  20. Two methods for absolute calibration of dynamic pressure transducers

    Science.gov (United States)

    Swift, G. W.; Migliori, A.; Garrett, S. L.; Wheatley, J. C.

    1982-12-01

    Two techniques are described for absolute calibration of a dynamic pressure transducer from 0 to 400 Hz in 1-MPa helium gas. One technique is based on a comparison to a mercury manometer; the other is based on the principle of reciprocity. The two techniques agree within the instrumental uncertainties of 1%.

  1. Physical and chemical sensing using monolithic semiconductor optical transducers

    Science.gov (United States)

    Zappe, Hans P.; Hofstetter, Daniel; Maisenhoelder, Bernd; Moser, Michael; Riel, Peter; Kunz, Rino E.

    1997-09-01

    We present two monolithically integrated optical sensor systems based on semiconductor photonic integrated circuits. These compact, robust and highly functional transducers perform all necessary optical and electro-optical functions on-chip; extension to multi-sensor arrays is easily envisaged. A monolithic Michelson interferometer for high-resolution displacement measurement and a monolithic Mach-Zehnder interferometer for refractometry are discussed.

  2. Cooling method prolongs life of hot-wire transducer

    Science.gov (United States)

    Baldwin, L. V.; Sandborn, V. A.

    1964-01-01

    To cool a hot-wire transducer, the two ends of the wire are supported on thermally and electrically conductive rods, surrounded by a fluid cooling medium. By keeping the supporting rods at a substantially constant temperature, the probe is prevented from overheating.

  3. Neutron Irradiation Tests of Pressure Transducers in Liquid Helium

    CERN Document Server

    Amand, J F; Casas-Cubillos, J; Thermeau, J P

    1999-01-01

    The superconducting magnets of the future Large Hadron Collider (LHC) at CERN will operate in pressurised superfluid helium (1 bar, 1.9 K). About 500 pressure transducers will be placed in the liquid helium bath for monitoring the filling and the pressure transients after resistive transitions. Their precision must remain better than 100 mbar at pressures below 2 bar and better than 5% for higher pressures (up to 20 bar), with temperatures ranging from 1.8 K to 300 K. All the tested transducers are based on the same principle: the fluid or gas is separated from a sealed reference vacuum by an elastic membrane; its deformation indicates the pressure. The transducers will be exposed to high neutron fluence (2 kGy, 1014 n/cm2 per year) during the 20 years of machine operation. This irradiation may induce changes both on the membranes characteristics (leakage, modification of elasticity) and on gauges which measure their deformations. To investigate these effects and select the transducer to be used in the LHC, a...

  4. Acoustic impedance matching of piezoelectric transducers to the air.

    Science.gov (United States)

    Gómez Alvarez-Arenas, Tomás E

    2004-05-01

    The purpose of this work is threefold: to investigate material requirements to produce impedance matching layers for air-coupled piezoelectric transducers, to identify materials that meet these requirements, and to propose the best solution to produce air-coupled piezoelectric transducers for the low megahertz frequency range. Toward this end, design criteria for the matching layers and possible configurations are reviewed. Among the several factors that affect the efficiency of the matching layer, the importance of attenuation is pointed out. A standard characterization procedure is applied to a wide collection of candidate materials to produce matching layers. In particular, some types of filtration membranes are studied. From these results, the best materials are identified, and the better matching configuration is proposed. Four pairs of air-coupled piezoelectric transducers also are produced to illustrate the performance of the proposed solution. The lowest two-way insertion loss figure is -24 dB obtained at 0.45 MHz. This increases for higher frequency transducers up to -42 dB at 1.8 MHz and -50 at 2.25 MHz. Typical bandwidth is about 15-20%.

  5. Interdigitated interdigital transducer for surface elastometry of soft damping tissue.

    Science.gov (United States)

    Danicki, Eugene; Nowicki, Andrzej; Tasinkevych, Yuriy

    2013-06-01

    Measurement of the shear elastic constant of soft and highly damping tissue of high Poisson ratio is quite a challenging task. It is proposed to evaluate shear wave velocity and damping of tissue by measuring the shear skimming bulk waves using one interdigitated interdigital transducer on a piezoelectric layer, such as polyvinylidene fluoride, applied to the surface of the small tissue sample.

  6. Cantilever deflection measurement and actuation by an nterdigitated transducer

    NARCIS (Netherlands)

    Strambini, E.; Piazza, V.; Pingue, P.; Biasiol, G.; Sorba, L.; Beltram, F.

    2010-01-01

    A scheme that allows all-electrical high-bandwidth readout of a cantilever deflection by means of an integrated interdigitated transducer is presented. The present approach takes advantage of the piezoelectricity of the chosen cantilever substrate material to generate and detect surface-acoustic-wav

  7. Multilevel inverter based class D audio amplifier for capacitive transducers

    DEFF Research Database (Denmark)

    Nielsen, Dennis; Knott, Arnold; Andersen, Michael A. E.

    2014-01-01

    The reduced semiconductor voltage stress makes the multilevel inverters especially interesting, when driving capacitive transducers for audio applications. A ± 300 V flying capacitor class D audio amplifier driving a 100 nF load in the midrange region of 0.1-3.5 kHz with Total Harmonic Distortion...

  8. Characterization of HIFU transducers designed for sonochemistry application: Acoustic streaming.

    Science.gov (United States)

    Hallez, L; Touyeras, F; Hihn, J-Y; Bailly, Y

    2016-03-01

    Cavitation distribution in a High Intensity Focused Ultrasound sonoreactors (HIFU) has been extensively described in the recent literature, including quantification by an optical method (Sonochemiluminescence SCL). The present paper provides complementary measurements through the study of acoustic streaming generated by the same kind of HIFU transducers. To this end, results of mass transfer measurements (electrodiffusional method) were compared to optical method ones (Particle Image Velocimetry). This last one was used in various configurations: with or without an electrode in the acoustic field in order to have the same perturbation of the wave propagation. Results show that the maximum velocity is not located at the focal but shifted near the transducer, and that this shift is greater for high powers. The two cavitation modes (stationary and moving bubbles) are greatly affect the hydrodynamic behavior of our sonoreactors: acoustic streaming and the fluid generated by bubble motion. The results obtained by electrochemical measurements show the same low hydrodynamic activity in the transducer vicinity, the same shift of the active focal toward the transducer, and the same absence of activity in the post-focal axial zone. The comparison with theoretical Eckart's velocities (acoustic streaming in non-cavitating media) confirms a very high activity at the "sonochemical focal", accounted for by wave distortion, which induced greater absorption coefficients. Moreover, the equivalent liquid velocities are one order of magnitude larger than the ones measured by PIV, confirming the enhancement of mass transfer by bubbles oscillation and collapse close to the surface, rather than from a pure streaming effect.

  9. Investigation of inductively coupled ultrasonic transducer system for NDE.

    Science.gov (United States)

    Zhong, Cheng Huan; Croxford, Anthony J; Wilcox, Paul D

    2013-06-01

    Inductive coupling offers a simple solution to wirelessly probe ultrasonic transducers. This paper investigates the theory and feasibility of such an inductively coupled transducer system in the context of nondestructive evaluation (NDE) applications. The noncontact interface is based on electromagnetic coupling between three coils; one of the coils is physically connected to the transducer, the other two are in a separate probing unit, where they are connected to the transmit and receive channels of the instrumentation. The complete system is modeled as a three-port network with the measured impedance of a bonded piezoelectric ceramic disc representing a sensor attached to an arbitrary solid substrate. The developed transmission line model is a function of the physical parameters of the electromagnetic system, such as the number of turns and diameter of each coil, and their separation. This model provides immediate predictions of electrical input impedance and pulse-echo response. The model has been validated experimentally and a sensitivity analysis of the input parameters performed. This has enabled optimization of the various parameters. Inductively coupled transducer systems have been built for both bulk and guided wave examples. By using chirped excitation and baseline subtraction, inspection distance of up to 700 mm is achieved in single-shot, guided-wave pulse-echo mode measurements with a 5 mm separation between the probing coils and transducer coil on an aluminum plate structure. In the bulk wave example, a delamination in an 8.9-mm-thick carbon fiber composite specimen is successfully identified from the changes in the arrival time of a reflected pulse.

  10. A novel CMOS transducer for giant magnetoresistance sensors

    Science.gov (United States)

    Luong, Van Su; Lu, Chih-Cheng; Yang, Jing-Wen; Jeng, Jen-Tzong

    2017-02-01

    In this work, an ASIC (application specific integrated circuits) transducer circuit for field modulated giant magnetoresistance (GMR) sensors was designed and fabricated using a 0.18-μ m CMOS process. The transducer circuits consist of a frequency divider, a digital phase shifter, an instrument amplifier, and an analog mixer. These comprise a mix of analog and digital circuit techniques. The compact chip size of 1.5 mm × 1.5 mm for both analog and digital parts was achieved using the TSMC18 1P6M (1-polysilicon 6-metal) process design kit, and the characteristics of the system were simulated using an HSpice simulator. The output of the transducer circuit is the result of the first harmonic detection, which resolves the modulated field using a phase sensitive detection (PSD) technique and is proportional to the measured magnetic field. When the dual-bridge GMR sensor is driven by the transducer circuit with a current of 10 mA at 10 kHz, the observed sensitivity of the field sensor is 10.2 mV/V/Oe and the nonlinearity error was 3% in the linear range of ±1 Oe. The performance of the system was also verified by rotating the sensor system horizontally in earth's magnetic field and recording the sinusoidal output with respect to the azimuth angle, which exhibits an error of less than ±0.04 Oe. These results prove that the ASIC transducer is suitable for driving the AC field modulated GMR sensors applied to geomagnetic measurement.

  11. Measurements of attenuation coefficient for evaluating the hardness of a cataract lens by a high-frequency ultrasonic needle transducer

    Energy Technology Data Exchange (ETDEWEB)

    Huang, C.-C. [Department of Electronic Engineering, Fu Jen Catholic University, Taipei 24205, Taiwan (China); Chen Ruimin; Zhou Qifa; Shung, K Kirk [NIH Resource on Medical Ultrasonic Transducer Technology, Department of Biomedical Engineering, University of Southern California, Los Angeles, CA 90089 (United States); Tsui, P.-H. [Division of Mechanics, Research Center for Applied Sciences, Academia Sinica, Taipei 11529, Taiwan (China); Humayun, Mark S [Doheny Retina Institute, Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033 (United States)], E-mail: j648816n@ms23.hinet.net

    2009-10-07

    A cataract is a clouding of the lens in the eye that affects vision. Phacoemulsification is the mostly common surgical method for treating cataracts, and determining that the optimal phacoemulsification energy is dependent on measuring the hardness of the lens. This study explored the use of an ultrasound needle transducer for invasive measurements of ultrasound attenuation coefficient to evaluate the hardness of the cataract lens. A 47 MHz high-frequency needle transducer with a diameter of 0.9 mm was fabricated by a polarized PMN-33%PT single crystal in the present study. The attenuation coefficients at different stages of an artificial porcine cataract lens were measured using the spectral shift approach. The hardness of the cataract lens was also evaluated by mechanical measurement of its elastic properties. The results demonstrated that the ultrasonic attenuation coefficient was increased from 0.048 {+-} 0.02 to 0.520 {+-} 0.06 dB mm{sup -1} MHz{sup -1} corresponding to an increase in Young's modulus from 6 {+-} 0.4 to 96 {+-} 6.2 kPa as the cataract further developed. In order to evaluate the feasibility of combining needle transducer and phacoemulsification probe for real-time measurement during cataract surgery, the needle transducer was mounted on the phacoemulsification probe for a vibration test. The results indicated that there was no apparent damage to the tip of the needle transducer and the pulse-echo test showed that a good performance in sensitivity was maintained after the vibration test.

  12. Two-channel opto-acoustic diode laser spectrometer and fine structure of methane absorption spectra in 6070-6180 cm-1 region.

    Science.gov (United States)

    Kapitanov, V A; Ponomarev, Yu N; Tyryshkin, I S; Rostov, A P

    2007-04-01

    We describe the hardware and software of the high-sensitive two-channel opto-acoustic spectrometer with a near infrared diode laser. A semiconductor TEC-100 laser with outer resonator generates a continuous single-frequency radiation in the range of 6040-6300 cm-1 with spectral resolution better that 10 MHz. The newly designed model of photo-acoustic cells in the form of a ring type resonator was used in the spectrometer, and the system allows the measurement of a weak absorption coefficient equal to 1.4x10(-7) cm-1 Hz-1/2 with a laser radiation power of 0.003 W. The methane absorption spectra within a range of 6080-6180 cm-1 were measured with a spectral resolution of 10 MHz and the signal to noise ratio more than 10(3). Six hundred absorption lines were recorded, which is twice as many as in HITRAN-2004. The accurate measurements of the half-width and shift of methane unresolved triplet R3 of 2nu3 band permit us to determine values of the broadening and shift coefficients for CH4-air, CH4-N2, and CH4-SF6 mixtures.

  13. The measurement of tremor using a velocity transducer: comparison to simultaneous recordings using transducers of displacement, acceleration and muscle activity.

    Science.gov (United States)

    Norman, K E; Edwards, R; Beuter, A

    1999-10-15

    Precise kinematic measurements of tremor have historically been obtained using accelerometers. However, current technology permits precise measurements in velocity and displacement. The primary advantage of velocity recording is that only one step of integration or differentiation is required for either displacement or acceleration. A method is presented of measuring finger tremor using a laser system that transduces velocity precisely. Measurements of postural finger tremor thus obtained were compared to those simultaneously obtained from a laser system that transduces displacement, from an accelerometer and from surface electromyography (EMG) of the extensor digitorum communis. A range of amplitude and frequency content was obtained by testing control subjects and subjects with Parkinson's disease. The velocity transducer showed excellent correspondence of amplitude and frequency measurement with the displacement transducer. Measures of absolute and relative amplitude correlated well (r > or = 0.96 in amplitude measures in displacement, velocity and acceleration), and high coherence was found throughout the frequency range of interest. Measurements by the accelerometer generally showed poorer correspondence with those of the other instruments. EMG measurements showed good correspondence in some trials but poorer correspondence in others, attributed to the low level of muscle activity required in the task. Precise kinematic measurements appear to be highly sensitive to neuromotor impairment.

  14. Six-Axis Force-Torque Transducer for Mars 2018 Mission Project

    Data.gov (United States)

    National Aeronautics and Space Administration — A transducer element that is hearty enough for a Mars lander mission needs to be developed so that a six-axis force and torque transducer is possible. The technical...

  15. PMN-PT single crystal focusing transducer fabricated using a mechanical dimpling technique.

    Science.gov (United States)

    Lam, K H; Chen, Y; Cheung, K F; Dai, J Y

    2012-01-01

    A ∼5MHz focusing PMN-PT single crystal ultrasound transducer has been fabricated utilizing a mechanical dimpling technique, where the dimpled crystal wafer was used as an active element of the focusing transducer. For the dimpled focusing transducer, the effective electromechanical coupling coefficient was enhanced significantly from 0.42 to 0.56. The dimpled transducer also yields a -6dB bandwidth of 63.5% which is almost double the bandwidth of the plane transducer. An insertion loss of the dimpled transducer (-18.1dB) is much lower than that of the plane transducer. Finite element simulation also reveals specific focused beam from concave crystal surface. These promising results show that the dimpling technique can be used to develop high-resolution focusing single crystal transducers.

  16. Directional properties of an 18-KHZ transducer: Proprietes directionnelles d'un transducteur 18 KHZ

    National Research Council Canada - National Science Library

    Foote, K.G

    1993-01-01

    Several theoretical measures of directivity are given for an 18-kHz transducer that is used in both single-beam and split- beam applications, namely the SIMRAD transducer type 18-11 in the single-beam variant...

  17. Hybrid nanowire ion-to-electron transducers for integrated bioelectronic circuitry (Conference Presentation)

    Science.gov (United States)

    Carrad, Damon J.; Mostert, Bernard; Meredith, Paul; Micolich, Adam P.

    2016-09-01

    A key task in bioelectronics is the transduction between ionic/protonic signals and electronic signals at high fidelity. This is a considerable challenge since the two carrier types exhibit intrinsically different physics. We present our work on a new class of organic-inorganic transducing interface utilising semiconducting InAs and GaAs nanowires directly gated with a proton transporting hygroscopic polymer consisting of undoped polyethylene oxide (PEO) patterned to nanoscale dimensions by a newly developed electron-beam lithography process [1]. Remarkably, we find our undoped PEO polymer electrolyte gate dielectric [2] gives equivalent electrical performance to the more traditionally used LiClO4-doped PEO [3], with an ionic conductivity three orders of magnitude higher than previously reported for undoped PEO [4]. The observed behaviour is consistent with proton conduction in PEO. We attribute our undoped PEO-based devices' performance to the small external surface and high surface-to-volume ratio of both the nanowire conducting channel and patterned PEO dielectric in our devices, as well as the enhanced hydration afforded by device processing and atmospheric conditions. In addition to studying the basic transducing mechanisms, we also demonstrate high-fidelity ionic to electronic conversion of a.c. signals at frequencies up to 50 Hz. Moreover, by combining complementary n- and p-type transducers we demonstrate functional hybrid ionic-electronic circuits can achieve logic (NOT operation), and with some further engineering of the nanowire contacts, potentially also amplification. Our device structures have significant potential to be scaled towards realising integrated bioelectronic circuitry. [1] D.J. Carrad et al., Nano Letters 14, 94 (2014). [2] D.J. Carrad et al., Manuscript in preparation (2016). [3] S.H. Kim et al., Advanced Materials 25, 1822 (2013). [4] S.K. Fullerton-Shirey et al., Macromolecules 42, 2142 (2009).

  18. Influenza virus-specific TCR-transduced T cells as a model for adoptive immunotherapy.

    Science.gov (United States)

    Berdien, Belinda; Reinhard, Henrike; Meyer, Sabrina; Spöck, Stefanie; Kröger, Nicolaus; Atanackovic, Djordje; Fehse, Boris

    2013-06-01

    Adoptive transfer of T lymphocytes equipped with tumor-antigen specific T-cell receptors (TCRs) represents a promising strategy in cancer immunotherapy, but the approach remains technically demanding. Using influenza virus (Flu)-specific T-cell responses as a model system we compared different methods for the generation of T-cell clones and isolation of antigen-specific TCRs. Altogether, we generated 12 CD8(+) T-cell clones reacting to the Flu matrix protein (Flu-M) and 6 CD4(+) T-cell clones reacting to the Flu nucleoprotein (Flu-NP) from 4 healthy donors. IFN-γ-secretion-based enrichment of antigen-specific cells, optionally combined with tetramer staining, was the most efficient way for generating T-cell clones. In contrast, the commonly used limiting dilution approach was least efficient. TCR genes were isolated from T-cell clones and cloned into both a previously used gammaretroviral LTR-vector, MP91 and the novel lentiviral self-inactivating vector LeGO-MP that contains MP91-derived promotor and regulatory elements. To directly compare their functional efficiencies, we in parallel transduced T-cell lines and primary T cells with the two vectors encoding identical TCRs. Transduction efficiencies were approximately twice higher with the gammaretroviral vector. Secretion of high amounts of IFN-γ, IL-2 and TNF-α by transduced cells after exposure to the respective influenza target epitope proved efficient specificity transfer of the isolated TCRs to primary T-cells for both vectors, at the same time indicating superior functionality of MP91-transduced cells. In conclusion, we have developed optimized strategies to obtain and transfer antigen-specific TCRs as well as designed a novel lentiviral vector for TCR-gene transfer. Our data may help to improve adoptive T-cell therapies.

  19. One-dimensional analysis of piezoelectric transducers based on Thevenin theorem

    OpenAIRE

    Arnold, FJ

    2009-01-01

    In this work, a method of analysis of piezoelectric transducers is shown. This method is based on the simplification of Mason's equivalent electric circuit. An adaptation of Thevenin theorem has been employed to study the behavior of piezoelectric transducers used as transmitters (electric into mechanic energy conversion). This study was restricted to transducers with a typical configuration employed in high power applications. The transducers were one-dimensionally modeled, considering only ...

  20. Modeling the radiation of ultrasonic phased-array transducers with Gaussian beams.

    Science.gov (United States)

    Huang, Ruiju; Schmerr, Lester W; Sedov, Alexander

    2008-12-01

    A new transducer beam model, called a multi-Gaussian array beam model, is developed to simulate the wave fields radiated by ultrasonic phased-array transducers. This new model overcomes the restrictions on using ordinary multi-Gaussian beam models developed for large single-element transducers in phased-array applications. It is demonstrated that this new beam model can effectively model the steered and focused beams of a linear phased-array transducer.

  1. Eddy Current Transducer Dedicated for Sigma Phase Evaluation in Duplex Stainless Steel

    Directory of Open Access Journals (Sweden)

    Grzegorz Psuj

    2012-01-01

    Full Text Available The paper describes a new transducer dedicated for evaluation of a duplex stainless steel (DSS. Different phases which exist in DSS have influence on mechanical as well as on electrical properties. Therefore, an eddy current transducer was utilized. In order to achieve high sensitivity, a differential type of the transducer was selected. The performance of the transducer was verified by utilizing the samples which had a different amount of sigma phase.

  2. Progress towards developing neutron tolerant magnetostrictive and piezoelectric transducers

    Science.gov (United States)

    Reinhardt, Brian; Tittmann, Bernhard; Rempe, Joy; Daw, Joshua; Kohse, Gordon; Carpenter, David; Ames, Michael; Ostrovsky, Yakov; Ramuhalli, Pradeep; Montgomery, Robert; Chien, Hualte; Wernsman, Bernard

    2015-03-01

    Current generation light water reactors (LWRs), sodium cooled fast reactors (SFRs), small modular reactors (SMRs), and next generation nuclear plants (NGNPs) produce harsh environments in and near the reactor core that can severely tax material performance and limit component operational life. To address this issue, several Department of Energy Office of Nuclear Energy (DOE-NE) research programs are evaluating the long duration irradiation performance of fuel and structural materials used in existing and new reactors. In order to maximize the amount of information obtained from Material Testing Reactor (MTR) irradiations, DOE is also funding development of enhanced instrumentation that will be able to obtain in-situ, real-time data on key material characteristics and properties, with unprecedented accuracy and resolution. Such data are required to validate new multi-scale, multi-physics modeling tools under development as part of a science-based, engineering driven approach to reactor development. It is not feasible to obtain high resolution/microscale data with the current state of instrumentation technology. However, ultrasound-based sensors offer the ability to obtain such data if it is demonstrated that these sensors and their associated transducers are resistant to high neutron flux, high gamma radiation, and high temperature. To address this need, the Advanced Test Reactor National Scientific User Facility (ATR-NSUF) is funding an irradiation, led by PSU, at the Massachusetts Institute of Technology Research Reactor to test the survivability of ultrasound transducers. As part of this effort, PSU and collaborators have designed, fabricated, and provided piezoelectric and magnetostrictive transducers that are optimized to perform in harsh, high flux, environments. Four piezoelectric transducers were fabricated with either aluminum nitride, zinc oxide, or bismuth titanate as the active element that were coupled to either Kovar or aluminum waveguides and two

  3. Progress towards developing neutron tolerant magnetostrictive and piezoelectric transducers

    Energy Technology Data Exchange (ETDEWEB)

    Reinhardt, Brian; Tittmann, Bernhard [The Pennsylvania State University (United States); Rempe, Joy; Daw, Joshua [Idaho National Laboratory (United States); Kohse, Gordon; Carpenter, David; Ames, Michael; Ostrovsky, Yakov [Massachusetts Institute of Technology (United States); Ramuhalli, Pradeep; Montgomery, Robert [Pacific Northwest National Laboratory (United States); Chien, Hualte [Argonne National Laboratory (United States); Wernsman, Bernard [Bechtel Marine Propulsion Corp (United States)

    2015-03-31

    Current generation light water reactors (LWRs), sodium cooled fast reactors (SFRs), small modular reactors (SMRs), and next generation nuclear plants (NGNPs) produce harsh environments in and near the reactor core that can severely tax material performance and limit component operational life. To address this issue, several Department of Energy Office of Nuclear Energy (DOE-NE) research programs are evaluating the long duration irradiation performance of fuel and structural materials used in existing and new reactors. In order to maximize the amount of information obtained from Material Testing Reactor (MTR) irradiations, DOE is also funding development of enhanced instrumentation that will be able to obtain in-situ, real-time data on key material characteristics and properties, with unprecedented accuracy and resolution. Such data are required to validate new multi-scale, multi-physics modeling tools under development as part of a science-based, engineering driven approach to reactor development. It is not feasible to obtain high resolution/microscale data with the current state of instrumentation technology. However, ultrasound-based sensors offer the ability to obtain such data if it is demonstrated that these sensors and their associated transducers are resistant to high neutron flux, high gamma radiation, and high temperature. To address this need, the Advanced Test Reactor National Scientific User Facility (ATR-NSUF) is funding an irradiation, led by PSU, at the Massachusetts Institute of Technology Research Reactor to test the survivability of ultrasound transducers. As part of this effort, PSU and collaborators have designed, fabricated, and provided piezoelectric and magnetostrictive transducers that are optimized to perform in harsh, high flux, environments. Four piezoelectric transducers were fabricated with either aluminum nitride, zinc oxide, or bismuth titanate as the active element that were coupled to either Kovar or aluminum waveguides and two

  4. Forced and free displacement characterization of ionic polymer transducers

    Science.gov (United States)

    Akle, Barbar J.; Duncan, Andrew; Akle, Etienne; Wallmersperger, Thomas; Leo, Donald J.

    2009-03-01

    Ionic polymer transducers (IPT), sometimes referred to as artificial muscles, are known to generate a large bending strain and a moderate stress at low applied voltages (transducers. In this study, extensional IPTs are characterized under forced and free displacement boundary condition as a function of transducer architecture. The electrode thickness is varied from 10 μm up to 40 μm while three extensional actuators with Lithium, Cesium, and tetraethylammonium (TEA) mobile cations are characterized. Three fixtures are built in order to characterize the extensional actuation response. The first fixture measures the free displacement of an IPT sample sandwiched between two aluminum plates glued using the electrically conductive silver paste. In the second fixture a spring is compressed against the test sample with variable amounts to generate different levels of pre-stress and prevents the bending of the IPT. In the third fixture dead weights are placed on top of the sample in order to prevent bending. In the spring loaded fixture a thermocouple is placed in the proximity of the actuator and temperature is measured. The different transducers are characterized using a step voltage input and an alternating current (AC) sine wave input. The step input resulted in a logarithmic rise like displacement curve, while the low frequency (wave displacement response with a strong first harmonic. The high frequency AC excitation generated a response similar to that of the step input. Comparing the measured temperature for step and AC response demonstrated that the sample is heating up when exited with a high frequency signal; which is leading to the expansion of the sample. Initial experimental results demonstrate a strong correlation between electrode architecture and the peak strain response. Strains on the order of 2% are observed with air stable ionic liquid based transducers. A correlation between the strain and charge buildup in the polymer is also characterized. Cesium

  5. 21 CFR 870.2900 - Patient transducer and electrode cable (including connector).

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Patient transducer and electrode cable (including... § 870.2900 Patient transducer and electrode cable (including connector). (a) Identification. A patient transducer and electrode cable (including connector) is an electrical conductor used to transmit signals from...

  6. Experimental analysis of 1-3 piezocomposites for high-intensity focused ultrasound transducer applications.

    Science.gov (United States)

    Chen, Gin-Shin; Liu, Hsin-Chih; Lin, Yu-Cheng; Lin, Yu-Li

    2013-01-01

    Piezocomposites with 1-3 connectivity have been extensively used in medical imaging transducers and high-intensity focused ultrasound transducers, but most studies of 1-3 piezocomposites address medical imaging applications. The purpose of this study was to completely investigate 1-3 composites specifically for high-power ultrasonic transducer applications via a series of experimental analyses. PZT4-epoxy composite focused transducers with various aspect ratios and volume fractions were constructed in-house for the evaluation of the coupling factor, dielectric loss tangent, quality factor, bandwidth, acoustic impedance, and electroacoustic efficiency. The experimental analyses demonstrated that although the coupling factor of composite transducers was higher than that of the ceramic transducer, the composite transducers had a lower efficiency due to the high dielectric loss and high mechanical energy loss of the composites. In addition, the bandwidth and acoustic impedance of composite transducers were superior to the ceramic transducer. For the composite transducers, the efficiency and acoustic impedance were inversely proportional to the aspect ratio and linearly proportional to the volume fraction. The coupling of inter pillars that are too close to each other could cause a significant decrease in the efficiency of the composite transducer. With an appropriate design in terms of the aspect ratio, volume fraction, and PZT-pillar spacing, a high-efficiency composite high-intensity focused ultrasound transducer can be achieved.

  7. A process chain for integrating piezoelectric transducers into aluminum die castings to generate smart lightweight structures

    Science.gov (United States)

    Stein, Stefan; Wedler, Jonathan; Rhein, Sebastian; Schmidt, Michael; Körner, Carolin; Michaelis, Alexander; Gebhardt, Sylvia

    The application of piezoelectric transducers to structural body parts of machines or vehicles enables the combination of passive mechanical components with sensor and actuator functions in one single structure. According to Herold et al. [1] and Staeves [2] this approach indicates significant potential regarding smart lightweight construction. To obtain the highest yield, the piezoelectric transducers need to be integrated into the flux of forces (load path) of load bearing structures. Application in a downstream process reduces yield and process efficiency during manufacturing and operation, due to the necessity of a subsequent process step of sensor/actuator application. The die casting process offers the possibility for integration of piezoelectric transducers into metal structures. Aluminum castings are particularly favorable due to their high quality and feasibility for high unit production at low cost (Brunhuber [3], Nogowizin [4]). Such molded aluminum parts with integrated piezoelectric transducers enable functions like active vibration damping, structural health monitoring or energy harvesting resulting in significant possibilities of weight reduction, which is an increasingly important driving force of automotive and aerospace industry (Klein [5], Siebenpfeiffer [6]) due to increasingly stringent environmental protection laws. In the scope of those developments, this paper focuses on the entire process chain enabling the generation of lightweight metal structures with sensor and actuator function, starting from the manufacturing of piezoelectric modules over electrical and mechanical bonding to the integration of such modules into aluminum (Al) matrices by die casting. To achieve this challenging goal, piezoceramic sensors/actuator modules, so-called LTCC/PZT modules (LPM) were developed, since ceramic based piezoelectric modules are more likely to withstand the thermal stress of about 700 °C introduced by the casting process (Flössel et al., [7]). The

  8. Transducer finite aperture effects in sound transmission near leaky Lamb modes in elastic plates at normal incidence

    CERN Document Server

    Aanes, Magne; Lunde, Per; Vestrheim, Magne

    2016-01-01

    The interaction of ultrasonic waves with fluid-embedded viscoelastic plates, pipes, and shells, have been subject to extensive theoretical and experimental studies over several decades. In normal-incidence through-transmission measurements of a water-embedded solid plate using ultrasonic piezoelectric transducer sound fields, significant deviations from plane wave theory have recently been observed. To quantitatively describe such measured phenomena, finite element modeling (FEM), also combined with an angular spectrum method (ASM), have been used for three-dimensional (3D) simulation of the voltage-to-sound-pressure signal propagation through the electro-acoustic measurement system consisting of the piezoelectric transducer, the water-embedded steel plate, and the fluid regions at both sides of the plate. The observed phenomena of frequency downshift of the plate resonance, increased sound pressure level through the plate, and beam narrowing / widening, are ascribed to the finite angular spectrum of the beam...

  9. Modeling of nonlinear responses for reciprocal transducers involving polarization switching

    DEFF Research Database (Denmark)

    Willatzen, Morten; Wang, Linxiang

    2007-01-01

    Nonlinearities and hysteresis effects in a reciprocal PZT transducer are examined by use of a dynamical mathematical model on the basis of phase-transition theory. In particular, we consider the perovskite piezoelectric ceramic in which the polarization process in the material can be modeled....... We present numerical results for the reciprocal-transducer system and identify the influence of nonlinearities on the system dynamics at high and low frequency as well as electrical impedance effects due to tuning by a series inductance. It is found that nonlinear effects are not important at high...... by Landau theory for the first-order phase transformation, in which each polarization state is associated with a minimum of the Landau free-energy function. Nonlinear constitutive laws are obtained by using thermodynamical equilibrium conditions, and hysteretic behavior of the material can be modeled...

  10. Broadband electrostatic acoustic transducer for ultrasonic measurements in liquids.

    Science.gov (United States)

    Cantrell, J H; Heyman, J S; Yost, W T; Torbett, M A; Breazeale, M A

    1979-01-01

    A broadband capacitive electrostatic acoustic transducer (ESAT) has been developed for use in a liquid environment at megahertz frequencies. The ESAT basically consists of a thin conductive membrane stretched over a metallic housing. The membrane functions as the ground plate of a parallel plate capacitor, the other plate being a dc biased electrode recessed approximately 10 mum from the electrically grounded membrane. An ultrasonic wave incident on the membrane varies the membrane-electrode gap spacing and generates an electrical signal proportional to the wave amplitude. The entire assembly is sealed for immersion in a liquid environment. Calibration of the ESAT with incident ultrasonic waves of constant displacement amplitude from 1 to 15 MHz reveals a decrease in signal response with increasing frequency independent of membrane tension. The use of the ESAT as a broadband ultrasonic transducer in liquids with a predictable frequency response is promising.

  11. Force transducers based on the stress dependence of coercive force

    Science.gov (United States)

    Garshelis, I. J.

    1993-05-01

    An alternative measurement regime for magnetoelastic force transducers, based on variations in coercive field, is described. Hc is shown to be more directly related to the primary magnetic influence of stress, namely, the orientation of effective anisotropy, than conventionally used magnetization related parameters. The stress dependence of Hc is shown to generally reflect opposing factors associated with rotational and wall displacement magnetization reversal processes. In materials wherein Hc≪K/Ms wall motion dominates and if the product of λs/K and yield stress is high enough, large monotonic reductions of Hc with positive (tensile) stress are shown to be possible. A more complex variation of Hc with increasing compression is similarly expected. Experimental results from a transducer having an 18% Ni maraging steel core support these expectations.

  12. CMOS biosensors for in vitro diagnosis - transducing mechanisms and applications.

    Science.gov (United States)

    Lei, Ka-Meng; Mak, Pui-In; Law, Man-Kay; Martins, Rui P

    2016-09-21

    Complementary metal oxide semiconductor (CMOS) technology enables low-cost and large-scale integration of transistors and physical sensing materials on tiny chips (e.g., key functions of biosensors: transducing and signal processing. Recent CMOS biosensors unified different transducing mechanisms (impedance, fluorescence, and nuclear spin) and readout electronics have demonstrated competitive sensitivity for in vitro diagnosis, such as detection of DNA (down to 10 aM), protein (down to 10 fM), or bacteria/cells (single cell). Herein, we detail the recent advances in CMOS biosensors, centering on their key principles, requisites, and applications. Together, these may contribute to the advancement of our healthcare system, which should be decentralized by broadly utilizing point-of-care diagnostic tools.

  13. Electromechanical modelling of tapered ionic polymer metal composites transducers

    Directory of Open Access Journals (Sweden)

    Rakesha Chandra Dash

    2016-09-01

    Full Text Available Ionic polymer metal composites (IPMCs are relatively new smart materials that exhibit a bidirectional electromechanical coupling. IPMCs have large number of important engineering applications such as micro robotics, biomedical devices, biomimetic robotics etc. This paper presents a comparison between tapered and uniform cantilevered Nafion based IPMCs transducer. Electromechanical modelling is done for the tapered beam. Thickness can be varied according to the requirement of force and deflection. Numerical results pertaining to the force and deflection characteristics of both type IPMCs transducer are obtained. It is shown that the desired amount of force and deflections for tapered IPMCs can be achieved for a given voltage. Different fixed end (t0 and free end (t1 thickness values have been taken to justify the results using MATLAB.

  14. A novel design of micromachined capacitive Lamb wave transducers

    Science.gov (United States)

    Ge, Lifeng

    2006-11-01

    A new design for micromachined capacitive Lamb wave transducers (mCLWT) has been developed. The design is based on a theoretical TDK model previously developed for groove ultrasonic transducers. By the investigation of the dynamic behavior of a rectangular high aspect ratio diaphragm of the mCLWTs, the second order bending mode of the diaphragm is exploited to excite and detect Lamb wave. The new exiting mechanism can minimize the energy of the acoustic radiation at the normal direction of the diaphragm so as to provide more energy coupled into the Lamb wave in the silicon substrate. Also, the natural frequencies and mode shapes of such a mCLWT can be determined accurately from its geometry and materials used, so the TDK model provides guidance for the optimal design of mCLWTs.

  15. New Soft Polymeric Materials Applicable as Elastomeric Transducers

    DEFF Research Database (Denmark)

    Bejenariu, Anca Gabriela; Skov, Anne Ladegaard

    between two compliant electrodes will reduce its thickness and expand its area. The electrical energy transformed into mechanical energy is called actuation and it is studied in the technology of elastomeric transducers. While DEs deform under high voltage, the actuation varies for different materials......). In the present study hyperswollen silicone networks are synthesized and rheologically characterized. Their viscoelastic properties make them good candidates for elastomeric transducers. Silicone networks are synthesized using a hydrosilylation reaction at room temperature between vinyl-terminated polydimethyl......An elastomer is a material characterized by the capability to regain its original size and shape after being deformed (stretched or distorted). An ideal elastomer for electroactive polymer (EAP) applications is a system characterized by high extensibility, flexibility and a good mechanical fatigue...

  16. The copying power of one-state tree transducers

    DEFF Research Database (Denmark)

    Engelfriet, Joost; Skyum, Sven

    1982-01-01

    One-state deterministic top-down tree transducers (or, tree homomorphisms) cannot handle “prime copying,” i.e., their class of output (string) languages is not closed under the operation L → {$(w$)f(n) short parallel w ε L, f(n) greater-or-equal, slanted 1}, where f is any integer function whose...... range contains numbers with arbitrarily large prime factors (such as a polynomial). The exact amount of nonclosure under these copying operations is established for several classes of input (tree) languages. These results are relevant to the extended definable (or, restricted parallel level) languages......, to the syntax-directed translation of context-free languages, and to the tree transducer hierarchy....

  17. FOULING DETECTION IN FOOD VESSELS USING INTERDIGITAL LAMB WAVE TRANSDUCER

    Institute of Scientific and Technical Information of China (English)

    JIAO Jingpin; GE Haiyan; WU Bin; HE Cunfu

    2007-01-01

    Lamb waves are used to detect fouling in food vessels. The propagation of the Lamb waves in plates exhibits many modes and dispersion characteristics, which have great influence on fouling detection. The relative distribution of the in-plane and out-of-plane displacement of the mode across the thickness of the plate will determine the sensitivity of the mode to a particular loading condition. By considering the dispersion and multi-mode characteristics of guided waves, an interdigital polyvinylidene fluoride (PVDF) transducer is designed to realize the mode selection of guided waves, and a single α0 mode is used for guided wave detection. Fouling detection experiments are conducted in the laboratory using epoxy adhesive on a thin plate. Using the interdigital PVDF transducer, three fouled areas are detected. Using one of the time-frequency analysis methods, the waveforms are further processed. This also demonstrates the validity of this method of fouling detection.

  18. Unscented transform-based uncertainty analysis of rotating coil transducers for field mapping

    Science.gov (United States)

    Arpaia, P.; De Matteis, E.; Schiano Lo Moriello, R.

    2016-03-01

    The uncertainty of a rotating coil transducer for magnetic field mapping is analyzed. Unscented transform and statistical design of experiments are combined to determine magnetic field expectation, standard uncertainty, and separate contributions of the uncertainty sources. For nonlinear measurement models, the unscented transform-based approach is more error-proof than the linearization underlying the "Guide to the expression of Uncertainty in Measurements" (GUMs), owing to the absence of model approximations and derivatives computation. When GUM assumptions are not met, the deterministic sampling strategy strongly reduces computational burden with respect to Monte Carlo-based methods proposed by the Supplement 1 of the GUM. Furthermore, the design of experiments and the associated statistical analysis allow the uncertainty sources domain to be explored efficiently, as well as their significance and single contributions to be assessed for an effective setup configuration. A straightforward experimental case study highlights that a one-order-of-magnitude reduction in the relative uncertainty of the coil area produces a decrease in uncertainty of the field mapping transducer by a factor of 25 with respect to the worst condition. Moreover, about 700 trials and the related processing achieve results corresponding to 5 × 106 brute-force Monte Carlo simulations.

  19. Finite element analysis of hysteresis effects in piezoelectric transducers

    Science.gov (United States)

    Simkovics, Reinhard; Landes, Hermann; Kaltenbacher, Manfred; Hoffelner, Johann; Lerch, Reinhard

    2000-06-01

    The design of ultrasonic transducers for high power applications, e.g. in medical therapy or production engineering, asks for effective computer aided design tools to analyze the occurring nonlinear effects. In this paper the finite-element-boundary-element package CAPA is presented that allows to model different types of electromechanical sensors and actuators. These transducers are based on various physical coupling effects, such as piezoelectricity or magneto- mechanical interactions. Their computer modeling requires the numerical solution of a multifield problem, such as coupled electric-mechanical fields or magnetic-mechanical fields as well as coupled mechanical-acoustic fields. With the reported software environment we are able to compute the dynamic behavior of electromechanical sensors and actuators by taking into account geometric nonlinearities, nonlinear wave propagation and ferroelectric as well as magnetic material nonlinearities. After a short introduction to the basic theory of the numerical calculation schemes, two practical examples will demonstrate the applicability of the numerical simulation tool. As a first example an ultrasonic thickness mode transducer consisting of a piezoceramic material used for high power ultrasound production is examined. Due to ferroelectric hysteresis, higher order harmonics can be detected in the actuators input current. Also in case of electrical and mechanical prestressing a resonance frequency shift occurs, caused by ferroelectric hysteresis and nonlinear dependencies of the material coefficients on electric field and mechanical stresses. As a second example, a power ultrasound transducer used in HIFU-therapy (high intensity focused ultrasound) is presented. Due to the compressibility and losses in the propagating fluid a nonlinear shock wave generation can be observed. For both examples a good agreement between numerical simulation and experimental data has been achieved.

  20. Progress towards developing neutron tolerant magnetostrictive and piezoelectric transducers

    Energy Technology Data Exchange (ETDEWEB)

    Reinhardt, Brian [Pennsylvania State Univ., University Park, PA (United States). Dept. of Engineering Science and Mechanics; Tittmann, Bernhard [Pennsylvania State Univ., University Park, PA (United States). Dept. of Engineering Science and Mechanics; Rempe, Joy [Idaho National Lab. (INL), Idaho Falls, ID (United States); Daw, Joshua [Idaho National Lab. (INL), Idaho Falls, ID (United States); Kohse, Gordon [MIT (Massachusetts Inst. of Technology), Cambridge, MA (United States). MIT Nuclear Reactor Lab.; Carpenter, David [MIT (Massachusetts Inst. of Technology), Cambridge, MA (United States). MIT Nuclear Reactor Lab.; Ames, Micheal [MIT (Massachusetts Inst. of Technology), Cambridge, MA (United States). MIT Nuclear Reactor Lab.; Ostrovsky, Yakov [MIT (Massachusetts Inst. of Technology), Cambridge, MA (United States). MIT Nuclear Reactor Lab.; Ramuhalli, Pradeep [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Montgomery, Robert [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Chien, Hualte [Argonne National Lab. (ANL), Argonne, IL (United States); Wernsman, Bernard [Bettis Atomic Power Lab. (BAPL), West Mifflin, PA (United States). Bechtel Marine Propulsion Corp.

    2014-07-01

    Current generation light water reactors (LWRs), sodium cooled fast reactors (SFRs), small modular reactors (SMRs), and next generation nuclear plants (NGNPs) provide harsh environments in and near the core that can severely test material performance and limit their operational life. To address this issue, several Department of Energy Office of Nuclear Energy (DOE-NE) research programs are evaluating the long duration radiation performance of fuels and materials. In To reduce the amount of Material and Test Reactor (MTR) irradiations required, DOE is also funding development of enhanced instrumentation that will be able to obtain data, with unprecedented accuracy and resolution, that are required to validate new multi-scale multiphysics modeling tools . It is not feasible to obtain such data with the current state of instrumentation technology. To address this need, PSU and collaborators have started an experiment to test the potential for utilizing ultrasonic instruments in-pile. Ultrasonic sensors must be resistant to high neutron flux, high gamma radiation, and high temperature. PSU and collaborators have designed, fabricated, and started to irradiate piezoelectric and magnetostrictive transducers designed to perform in such harsh environments. Three piezoelectric transducers were fabricated with aluminum nitride, zinc oxide, and bismuth titanate as the active element. The transducers are coupled kovar and aluminum waveguides of which pulse-echo ultrasonic measurements are made in-situ. Two magnetostrictive transducers were fabricated with Remendur and Arnokrome as the active elements. These devices will be pulsed and monitored in-situ. (1) Selection of candidate sensor materials as well as optimization of test assembly parameters (2) High temperature benchmark testing and (3) initial data from the irradiation will be reported.