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Sample records for optimal tsp tour

  1. Certification of an optimal TSP tour through 85,900 cities

    DEFF Research Database (Denmark)

    Applegate, David L.; Bixby, Robert E.; Chvatal, Vasek

    2009-01-01

    We describe a computer code and data that together certify the optimality of a solution to the 85,900-city traveling salesman problem pla85900, the largest instance in the TSPLIB collection of challenge problems......We describe a computer code and data that together certify the optimality of a solution to the 85,900-city traveling salesman problem pla85900, the largest instance in the TSPLIB collection of challenge problems...

  2. TSP tour domination and Hamilton cycle decompositions of regular digraphs

    DEFF Research Database (Denmark)

    Gutin, Gregory; Yeo, Anders

    2001-01-01

    by the relative performance compared to the optimal value. In particular, we show that for the asymmetric traveling salesman problem, there is a deterministic polynomial time algorithm that finds a tour that is at least as good as the median of all tour values. Our algorithm uses an unpublished theorem...

  3. Heuristics for Comparing the Lengths of Completed E-TSP Tours: Crossings and Areas

    Science.gov (United States)

    MacGregor, James N.

    2017-01-01

    The article reports three experiments designed to explore heuristics used in comparing the lengths of completed Euclidean Traveling Salesman Problem (E-TSP) tours. The experiments used paired comparisons in which participants judged which of two completed tours of the same point set was shorter. The first experiment manipulated two factors, the…

  4. in-town tour optimization town tour optimization town tour

    African Journals Online (AJOL)

    eobe

    operation was formulated as a Traveling Salesman Problem on Excel spreadsheet. The results ... 19.27 %, tour time by 0.33-22.80 %, and fuel consumption. 22.80 %, and fuel ..... solving TSPs and reports a real world in-town tour improvement ...

  5. INTEGRATING CASE-BASED REASONING, KNOWLEDGE-BASED APPROACH AND TSP ALGORITHM FOR MINIMUM TOUR FINDING

    Directory of Open Access Journals (Sweden)

    Hossein Erfani

    2009-07-01

    Full Text Available Imagine you have traveled to an unfamiliar city. Before you start your daily tour around the city, you need to know a good route. In Network Theory (NT, this is the traveling salesman problem (TSP. A dynamic programming algorithm is often used for solving this problem. However, when the road network of the city is very complicated and dense, which is usually the case, it will take too long for the algorithm to find the shortest path. Furthermore, in reality, things are not as simple as those stated in AT. For instance, the cost of travel for the same part of the city at different times may not be the same. In this project, we have integrated TSP algorithm with AI knowledge-based approach and case-based reasoning in solving the problem. With this integration, knowledge about the geographical information and past cases are used to help TSP algorithm in finding a solution. This approach dramatically reduces the computation time required for minimum tour finding.

  6. Tour Route Multiobjective Optimization Design Based on the Tourist Satisfaction

    Directory of Open Access Journals (Sweden)

    Yan Han

    2014-01-01

    Full Text Available The question prompted is how to design the tour route to make the tourists get the maximum satisfactions considering the tourists’ demand. The influence factors of the tour route choices of tourists were analyzed and tourists’ behavior characteristics and psychological preferences were regarded as the important influence factors based on the tourist behavioral theories. A questionnaire of tourists’ tour route information and satisfaction degree was carried out. Some information about the scene spot and tourists demand and tour behaviors characteristic such as visit frequency, number of attractions visited was obtained and analyzed. Based on the convey datum, tour routes multiobjective optimization functions were prompted for the tour route design regarding the maximum satisfaction and the minimum tour distance as the optimal objective. The available routes are listed and categorized. Based on the particle swarm optimization model, the priorities of the tour route are calculated and finally the suggestion depth tour route and quick route tour routes are given considering the different tour demands of tourists. The results can offer constructive suggestions on how to design tour routes on the part of tourism enterprises and how to choose a proper tour route on the part of tourists.

  7. On approximately fair cost allocation in Euclidean TSP games

    NARCIS (Netherlands)

    Faigle, U.; Fekete, Sándor P.; Hochstättler, Winfried; Kern, Walter

    1998-01-01

    We consider the problem of allocating the cost of an optimal traveling salesman tour in a fair way among the nodes visited; in particular, we focus on the case where the distance matrix of the underlying TSP problem satisfies the triangle inequality. We thereby use the model of TSP games in the

  8. Optimization Technique in Scheduling Duck Tours

    OpenAIRE

    Norhazwani M. Y.; Khoo; C. F.; Hasrul Nisham R.

    2011-01-01

    Tourism industries are rapidly increased for the last few years especially in Malaysia. In order to attract more tourists, Malaysian Governance encourages any effort to increase Malaysian tourism industry. One of the efforts in attracting more tourists in Malacca, Malaysia is a duck tour. Duck tour is an amphibious sightseeing tour that works in two types of engines, hence, it required a huge cost to operate and maintain the vehicle. To other country, it is not so new but...

  9. OPTIMAL TOUR CONSTRUCTIONS FOR MULTIPLE MOBILE ROBOTS

    Directory of Open Access Journals (Sweden)

    AMIR A. SHAFIE

    2011-04-01

    Full Text Available The attempts to use mobile robots in a variety of environments are currently being limited by their navigational capability, thus a set of robots must be configured for one specific environment. The problem of navigating an environment is the fundamental problem in mobile robotic where various methods including exact and heuristic approaches have been proposed to solve the problem. This paper proposed a solution to the navigation problem via the use of multiple robots to explore the environment employing heuristic methods to navigate the environment using a variant of a Traveling Salesman Problem (TSP known as Multiple Traveling Salesman Problem (M-TSP.

  10. The Application of Fitness Sharing Method in Evolutionary Algorithm to Optimizing the Travelling Salesman Problem (TSP

    Directory of Open Access Journals (Sweden)

    Nurmaulidar Nurmaulidar

    2015-04-01

    Full Text Available Travelling Salesman Problem (TSP is one of complex optimization problem that is difficult to be solved, and require quite a long time for a large number of cities. Evolutionary algorithm is a precise algorithm used in solving complex optimization problem as it is part of heuristic method. Evolutionary algorithm, like many other algorithms, also experiences a premature convergence phenomenon, whereby variation is eliminated from a population of fairly fit individuals before a complete solution is achieved. Therefore it requires a method to delay the convergence. A specific method of fitness sharing called phenotype fitness sharing has been used in this research. The aim of this research is to find out whether fitness sharing in evolutionary algorithm is able to optimize TSP. There are two concepts of evolutionary algorithm being used in this research. the first one used single elitism and the other one used federated solution. The two concepts had been tested to the method of fitness sharing by using the threshold of 0.25, 0.50 and 0.75. The result was then compared to a non fitness sharing method. The result in this study indicated that by using single elitism concept, fitness sharing was able to give a more optimum result for the data of 100-1000 cities. On the other hand, by using federation solution concept, fitness sharing can yield a more optimum result for the data above 1000 cities, as well as a better solution of data-spreading compared to the method without fitness sharing.

  11. On One Approach to TSP Structural Stability

    Directory of Open Access Journals (Sweden)

    Evgeny Ivanko

    2014-01-01

    Full Text Available In this paper we study an inverse approach to the traveling salesman reoptimization problem. Namely, we consider the case of the addition of a new vertex to the initial TSP data and fix the simple “adaptation” algorithm: the new vertex is inserted into an edge of the optimal tour. In the paper we consider the conditions describing the vertexes that can be inserted by this algorithm without loss of optimality, study the properties of stability areas, and address several model applications.

  12. Tour Route Multiobjective Optimization Design Based on the Tourist Satisfaction

    OpenAIRE

    Yan Han; Hongzhi Guan; Jiaying Duan

    2014-01-01

    The question prompted is how to design the tour route to make the tourists get the maximum satisfactions considering the tourists’ demand. The influence factors of the tour route choices of tourists were analyzed and tourists’ behavior characteristics and psychological preferences were regarded as the important influence factors based on the tourist behavioral theories. A questionnaire of tourists’ tour route information and satisfaction degree was carried out. Some information about the scen...

  13. Resolution and optimization methods for tour planning problems

    International Nuclear Information System (INIS)

    Vasserot, Jean-Pierre

    1976-12-01

    The aim of this study is to describe computerized methods for the resolution of the computer supported tour planning problem. After a presentation of this problem in operational research, the different existing methods of resolution are reviewed with the different approaches which have led to their elaboration. Different critics and comparisons are made on these methods and some improvements and new procedures are proposed, some of them allowing to solve more general problems. Finally, the structure of such a program, made at the CII to solve this kind of problem under multiple constraints is analysed [fr

  14. Ant Colony Optimization ACO For The Traveling Salesman Problem TSP Using Partitioning

    Directory of Open Access Journals (Sweden)

    Alok Bajpai

    2015-08-01

    Full Text Available Abstract An ant colony optimization is a technique which was introduced in 1990s and which can be applied to a variety of discrete combinatorial optimization problem and to continuous optimization. The ACO algorithm is simulated with the foraging behavior of the real ants to find the incremental solution constructions and to realize a pheromone laying-and-following mechanism. This pheromone is the indirect communication among the ants. In this paper we introduces the partitioning technique based on the divide and conquer strategy for the traveling salesman problem which is one of the most important combinatorial problem in which the original problem is partitioned into the group of sub problems. And then we apply the ant colony algorithm using candidate list strategy for each smaller sub problems. After that by applying the local optimization and combining the sub problems to find the good solution for the original problem by improving the exploration efficiency of the ants. At the end of this paper we have also be presented the comparison of result with the normal ant colony system for finding the optimal solution to the traveling salesman problem.

  15. Improving Web Learning through model Optimization using Bootstrap for a Tour-Guide Robot

    Directory of Open Access Journals (Sweden)

    Rafael León

    2012-09-01

    Full Text Available We perform a review of Web Mining techniques and we describe a Bootstrap Statistics methodology applied to pattern model classifier optimization and verification for Supervised Learning for Tour-Guide Robot knowledge repository management. It is virtually impossible to test thoroughly Web Page Classifiers and many other Internet Applications with pure empirical data, due to the need for human intervention to generate training sets and test sets. We propose using the computer-based Bootstrap paradigm to design a test environment where they are checked with better reliability

  16. Polynomial Approximation Algorithms for the TSP and the QAP with a Factorial Domination Number

    DEFF Research Database (Denmark)

    Gutin, Gregory; Yeo, Anders

    2002-01-01

    Glover and Punnen (J. Oper. Res. Soc. 48 (1997) 502) asked whether there exists a polynomial time algorithm that always produces a tour which is not worse than at least n!/p(n) tours for some polynomial p(n) for every TSP instance on n cities. They conjectured that, unless P = NP, the answer to t...

  17. The modification of hybrid method of ant colony optimization, particle swarm optimization and 3-OPT algorithm in traveling salesman problem

    Science.gov (United States)

    Hertono, G. F.; Ubadah; Handari, B. D.

    2018-03-01

    The traveling salesman problem (TSP) is a famous problem in finding the shortest tour to visit every vertex exactly once, except the first vertex, given a set of vertices. This paper discusses three modification methods to solve TSP by combining Ant Colony Optimization (ACO), Particle Swarm Optimization (PSO) and 3-Opt Algorithm. The ACO is used to find the solution of TSP, in which the PSO is implemented to find the best value of parameters α and β that are used in ACO.In order to reduce the total of tour length from the feasible solution obtained by ACO, then the 3-Opt will be used. In the first modification, the 3-Opt is used to reduce the total tour length from the feasible solutions obtained at each iteration, meanwhile, as the second modification, 3-Opt is used to reduce the total tour length from the entire solution obtained at every iteration. In the third modification, 3-Opt is used to reduce the total tour length from different solutions obtained at each iteration. Results are tested using 6 benchmark problems taken from TSPLIB by calculating the relative error to the best known solution as well as the running time. Among those modifications, only the second and third modification give satisfactory results except the second one needs more execution time compare to the third modifications.

  18. A Smooth Tour Construction Approach for a Mobile Robot with Kinematic Constraints

    Directory of Open Access Journals (Sweden)

    Ahmet Yazici

    2013-10-01

    Full Text Available Mobile robots are increasingly used for service-like applications in which the service points are known and the mobile robot starts from a starting location, visits all the service points requested and returns to the starting location. The tour construction problem in these applications can be treated as a Travelling Salesman Problem (TSP. Classical tour construction algorithms that are proposed for the TSP find tours do not consider robot kinematic constraints. These tours may have sharp turns at some service points. When a mobile robot follows such a tour, it stops, turns and speeds up again. Therefore, the robots waste a considerable amount of power and time. In these cases, tour smoothing can be used to overcome this problem. However, smoothing an existing tour may result in unnecessarily long tours. In this study, a Smooth Tour Construction (STC approach is proposed for mobile robots with kinematic constraints. The STC approach considers tour construction and tour smoothing concurrently. The logic behind the tour construction part of the approach is based on the Savings Algorithm (SA. The tour smoothing is based on Dubins' arc-line approach. Experiments are conducted for P3-DX robots in a laboratory environment. Comparisons are also drawn with various tour smoothing algorithms in simulation environments to demonstrate the effectiveness of the proposed STC approach.

  19. Touring Katutura!

    OpenAIRE

    Steinbrink, Malte; Buning, Michael; Legant, Martin; Schauwinhold, Berenike; Süßenguth, Tore

    2016-01-01

    Guided sightseeing tours of the former township of Katutura have been offered in Windhoek since the mid-1990s. City tourism in the Namibian capital had thus become, at quite an early point in time, part of the trend towards utilising poor urban areas for purposes of tourism – a trend that set in at the beginning of the same decade. Frequently referred to as “slum tourism” or “poverty tourism”, the phenomenon of guided tours around places of poverty has not only been causing some media sensati...

  20. Cassini Tour Atlas Automated Generation

    Science.gov (United States)

    Grazier, Kevin R.; Roumeliotis, Chris; Lange, Robert D.

    2011-01-01

    During the Cassini spacecraft s cruise phase and nominal mission, the Cassini Science Planning Team developed and maintained an online database of geometric and timing information called the Cassini Tour Atlas. The Tour Atlas consisted of several hundreds of megabytes of EVENTS mission planning software outputs, tables, plots, and images used by mission scientists for observation planning. Each time the nominal mission trajectory was altered or tweaked, a new Tour Atlas had to be regenerated manually. In the early phases of Cassini s Equinox Mission planning, an a priori estimate suggested that mission tour designers would develop approximately 30 candidate tours within a short period of time. So that Cassini scientists could properly analyze the science opportunities in each candidate tour quickly and thoroughly so that the optimal series of orbits for science return could be selected, a separate Tour Atlas was required for each trajectory. The task of manually generating the number of trajectory analyses in the allotted time would have been impossible, so the entire task was automated using code written in five different programming languages. This software automates the generation of the Cassini Tour Atlas database. It performs with one UNIX command what previously took a day or two of human labor.

  1. TETRAHEURÍSTICA SISTÉMICA (THS PARA EL TSP SYSTEMIC TETRAHEURISTIC FOR THE TSP

    Directory of Open Access Journals (Sweden)

    Jorge Iván Pérez Rave

    2010-08-01

    Full Text Available Este artículo presenta un novedoso método, basado en elementos del pensamiento sistémico, para solucionar instancias del problema del vendedor viajero (TSP, el cual es comparado en términos de eficacia y eficiencia con "nearest neighbour", "cheapest insertion", "two-wwy exchange improvement" y "branch and bound". El primer apartado introduce la optimización combinatoria, el segundo ofrece un marco de referencia, el tercero presenta la metodología empleada, el cuarto apartado presenta el desarrollo de la tetraheurística sistémica, seguido del análisis de varianza y de rangos de Duncan para los factores: método y cantidad de ciudades; este apartado finaliza con el análisis del comportamiento de la proporción de "fracasos" del algoritmo propuesto a medida que aumenta la complejidad del TSP. Como resultado se obtiene un método para resolver instancias del TSP, conformado por tres heurísticas misionales: 1."vecino más cercano", 2. "sacrificio cortoplacista" y 3. "traslado LIFO", y una de apoyo llamada "búsqueda derecha 4P4". El diseño de la heurística denominada "sacrificio cortoplacista" es inspirado en el análisis sistémico del "vecino más cercano", al cual se le identifica el arquetipo de "soluciones rápidas que fallan", con aplicación a decisiones cotidianas. La tetraheurística sistémica se destaca, respecto a las demás, en solución arrojada y en tiempo computacional consumido, especialmente cuando incrementa la complejidad del TSP.This paper presents a novel method to solve instances of the TSP. This method is comparable in effectiveness and efficiency with "nearest neighbour", "cheapest insertion", "two-way exchange improvement" and "branch and bound". The first section provides a literature review of the combinatorial optimization, the second provides a reference frame, the third the methodology used and the fourth contains, inter alia, system thinking, AxB factorial design and management tool CAP-DO. The fourth

  2. Automated Design of Propellant-Optimal, End-to-End, Low-Thrust Trajectories for Trojan Asteroid Tours

    Science.gov (United States)

    Stuart, Jeffrey; Howell, Kathleen; Wilson, Roby

    2013-01-01

    The Sun-Jupiter Trojan asteroids are celestial bodies of great scientific interest as well as potential resources offering water and other mineral resources for longterm human exploration of the solar system. Previous investigations under this project have addressed the automated design of tours within the asteroid swarm. This investigation expands the current automation scheme by incorporating options for a complete trajectory design approach to the Trojan asteroids. Computational aspects of the design procedure are automated such that end-to-end trajectories are generated with a minimum of human interaction after key elements and constraints associated with a proposed mission concept are specified.

  3. Visualizing guided tours

    DEFF Research Database (Denmark)

    Poulsen, Signe Herbers; Fjord-Larsen, Mads; Hansen, Frank Allan

    This paper identifies several problems with navigating and visualizing guided tours in traditional hypermedia systems. We discuss solutions to these problems, including the representation of guided tours as 3D metro maps with content preview. Issues regarding navigation and disorientation...

  4. Temperature Switch PCR (TSP: Robust assay design for reliable amplification and genotyping of SNPs

    Directory of Open Access Journals (Sweden)

    Mather Diane E

    2009-12-01

    Full Text Available Abstract Background Many research and diagnostic applications rely upon the assay of individual single nucleotide polymorphisms (SNPs. Thus, methods to improve the speed and efficiency for single-marker SNP genotyping are highly desirable. Here, we describe the method of temperature-switch PCR (TSP, a biphasic four-primer PCR system with a universal primer design that permits amplification of the target locus in the first phase of thermal cycling before switching to the detection of the alleles. TSP can simplify assay design for a range of commonly used single-marker SNP genotyping methods, and reduce the requirement for individual assay optimization and operator expertise in the deployment of SNP assays. Results We demonstrate the utility of TSP for the rapid construction of robust and convenient endpoint SNP genotyping assays based on allele-specific PCR and high resolution melt analysis by generating a total of 11,232 data points. The TSP assays were performed under standardised reaction conditions, requiring minimal optimization of individual assays. High genotyping accuracy was verified by 100% concordance of TSP genotypes in a blinded study with an independent genotyping method. Conclusion Theoretically, TSP can be directly incorporated into the design of assays for most current single-marker SNP genotyping methods. TSP provides several technological advances for single-marker SNP genotyping including simplified assay design and development, increased assay specificity and genotyping accuracy, and opportunities for assay automation. By reducing the requirement for operator expertise, TSP provides opportunities to deploy a wider range of single-marker SNP genotyping methods in the laboratory. TSP has broad applications and can be deployed in any animal and plant species.

  5. Implementasi Algoritma Best-First Search (BeFS pada Penyelesaian Traveling Salesman Problem (TSP (Studi Kasus: Perjalanan Wisata Di Kota Yogyakarta

    Directory of Open Access Journals (Sweden)

    Muchammad Abrori

    2015-10-01

    Full Text Available Yogyakarta offers many tourist attractions, from nature based tourism, culinary tourism until cultural tourism. With so many tourist attractions offered by Yogyakarta, tourist often finds it difficult to arrange their travel schedule (from choosing which tourist attractions to be visited until choosing which route tourist should takes to maximize their vacation time. Therefore, it’s required to have a way to determine the shortest tour route so tourist can make their tour in the Yogyakarta effective. This problem can be categorized as Traveling Salesman Problem (TSP case. There are a lot of methods can be used to find the shortest route in Travelling Salesman Problems (TSP case. To solve the problem, which is to find the shortest tour route in Yogyakarta, Algorithm Best-First Travelling will be used in this undergraduate thesis. The implementation of Algorithm Best-First Search to find the shortest tour route in Yogyakarta can be used to produce a solution for tourist to choose the shortest tour package and decide which route they should take. The premium tour package produces tour route from Adi Sucipto Airport-Gembira Loka Zoo- Purawisata-N’dalem Gamelan Hotel-Yogyakarta Palace-Benteng Vredeburg Museum-Taman Pintar-Tamansari-Adi Sucipto Airport with distance covered 20.297 meter. The middle tour package produces tour route from Tugu railway station-Benteng Vredeburg Museum- Taman Pintar-Yogyakarta Palace-Mawar Asri Hotel-Tamansari-Purawisata-Gembira Loka Zoo-Tugu railway station with distance covered 11.772 meter. The economy tour package produces tour route from Giwangan bus station- Gembira Loka zoo-Purawisata-Yogyakarta Palace-Mitra Hotel-Benteng Vredeburg Museum-Taman Pintar-Tamansari-Giwangan bus station with distance covered 14.037 meter.

  6. Solving Large-Scale TSP Using a Fast Wedging Insertion Partitioning Approach

    Directory of Open Access Journals (Sweden)

    Zuoyong Xiang

    2015-01-01

    Full Text Available A new partitioning method, called Wedging Insertion, is proposed for solving large-scale symmetric Traveling Salesman Problem (TSP. The idea of our proposed algorithm is to cut a TSP tour into four segments by nodes’ coordinate (not by rectangle, such as Strip, FRP, and Karp. Each node is located in one of their segments, which excludes four particular nodes, and each segment does not twist with other segments. After the partitioning process, this algorithm utilizes traditional construction method, that is, the insertion method, for each segment to improve the quality of tour, and then connects the starting node and the ending node of each segment to obtain the complete tour. In order to test the performance of our proposed algorithm, we conduct the experiments on various TSPLIB instances. The experimental results show that our proposed algorithm in this paper is more efficient for solving large-scale TSPs. Specifically, our approach is able to obviously reduce the time complexity for running the algorithm; meanwhile, it will lose only about 10% of the algorithm’s performance.

  7. IMPLEMENTASI ALGORITMA TSP DALAM PENYELESAIAN TRACKING PAKET PADA UNIT PROCESSING CENTER POS INDONESIA KOTA LHOKSEUMAWE ACEH

    Directory of Open Access Journals (Sweden)

    Richki Hardi

    2015-04-01

    Full Text Available Traveling salesperson problem-TSP problem is an optimization problem to find the optimal way for the traveling salesman who wants to visit several cities, and returned to the original departure city. TSP is a difficult problem when viewed from the point of computing. Several methods have been used to solve these problems but until now not been found mangkus algorithms to solve them. The easiest way to solve TSP is to try all possible routes and find the optimal route. However, at the time of the very practical now required to complete an algorithm that quickly so that the TSP solution obtained near optimal solutions.TSP is very precise algorithm used for solving complex optimization problems and solved difficult conventional methods. Route and distance data used to determine the optimal route in the system is obtained from the survey results at the post office Lhokseumawe. The results showed that the algorithm is the shortest route from the post office to post office Lhokseumawe, Meulaboh, Lhokseumawe is through the route - Bireun-Simpang Tiga-Takengon-Meulaboh with a total distance of 326 kilometers. The implementation of this system using the programming language PHP, MySQL, and Macromedia Flash.

  8. Establishing the tolerability and performance of tamarind seed polysaccharide (TSP in treating dry eye syndrome: results of a clinical study

    Directory of Open Access Journals (Sweden)

    Valente Cristiana

    2007-03-01

    Full Text Available Abstract Background One of the problems arising from available preparations for dry eye syndrome is the limited residence time of products on the ocular surface. In this paper, we look at an innovative new treatment for dry eye, tamarind seed polysaccharide (TSP. TSP possesses mucomimetic, mucoadhesive and pseudoplastic properties. The 'mucin-like' molecular structure of TSP is similar to corneal and conjunctival mucin 1 (MUC1, a transmembrane glycoprotein thought to play an essential role in protecting and wetting the corneal surface and may explain its increased retention on the eye surface. Methods The activity of TSP and hyaluronic acid (HA in the treatment of dry eye syndrome was compared in an open-label, randomised, single-centre clinical study. Thirty patients were randomised to receive three or more applications per day of either TSP 0.5%, TSP 1% or HA 0.2% (Hyalistil™ over a period of 90 days. The primary objective of tolerability was assessed by visual analogue scale (VAS, scoring of specific symptoms and the incidence of adverse events. Secondary objectives included improvement in stability of the precorneal tear film, subjective symptoms and corneal and conjunctival staining. Results TSP 0.5% and 1% were comparable to HA 0.2% with regard to both primary and secondary objective parameters. TSP 1% showed benefits over HA 0.2% for the subjective symptoms; trouble blinking, ocular burning and foreign body sensation. Conclusion This study suggests that TSP 0.5% and 1% offer at least equivalent relief to HA 0.2% for dry eye syndrome. All treatments demonstrated optimal tolerability and are suitable for frequent use in the therapy of dry eye. TSP 1% produced promising results in terms of improvements in certain patient symptoms and suggests benefits of the TSP formulation. This study paves the way for a larger study to further establish the performance and safety of TSP compared with HA and highlights the need to expand this therapeutic

  9. Touring the Low Countries

    NARCIS (Netherlands)

    Strien, van Kees

    1998-01-01

    Touring the Low Countries is an anthology of approximately forty travel documents by British tourists - journals, letters, and financial accounts - most of them published here for the first time.The United Provinces and the Spanish Netherlands, with all the variety of their contrasting cultural

  10. Interactive Mold House Tour

    Science.gov (United States)

    Get a quick glimpse of some of the most important ways to protect your home from mold by this interactive tour of the Mold House. Room-by-room, you'll learn about common mold issues and how to address them.

  11. Penanganan Fuzzy Time Window pada Travelling Salesman Problem (TSP dengan Penerapan Algoritma Genetika

    Directory of Open Access Journals (Sweden)

    Gusti Eka Yuliastuti

    2017-03-01

    Full Text Available The route of the travel tour packages offered by travel agents is not considered optimum, so the level of satisfaction the tourist is not maximal. Selection of the route of the travel packages included in the traveling salesman problem (TSP. The problem that occurs is uncertain tourists visiting destinations at the best destinations timing hereinafter be referred to as the fuzzy time window problem. Therefore, the authors apply the genetic algorithm to solve the problem. Based on test results obtained optimum solution with the fitness value of 1.3291, a population size of 100, the number of generations of 1000, a combination of CR=0,4 and MR=0.6.

  12. Deterministic algorithms for multi-criteria Max-TSP

    NARCIS (Netherlands)

    Manthey, Bodo

    2012-01-01

    We present deterministic approximation algorithms for the multi-criteria maximum traveling salesman problem (Max-TSP). Our algorithms are faster and simpler than the existing randomized algorithms. We devise algorithms for the symmetric and asymmetric multi-criteria Max-TSP that achieve ratios of

  13. Mass media tours Bangladesh.

    Science.gov (United States)

    1998-07-01

    In May 1998, representatives of Japan's mass media toured Bangladesh to learn about the country's reproductive health and population programs. The goal of the visit was for the journalists to spread information about the projects to their peers, to government officials, and parliamentarians responsible for allocations of foreign aid. The 1st stage of the visit involved meetings with program officials and organizers. In the 2nd stage, the journalists toured: 1) Matlab, where the International Center for Diarrhoeal Disease Research has been implementing an intensive family planning (FP) program; 2) the Panchdona IP area, where the Integrated Family Development Project is being conducted with funding from the Japanese government; 3) an FP office and satellite clinic; and 4) a site where voluntary organizations are providing FP/maternal-child health care. The journalists also learned about how micro-credit loans operate. Participating journalists reported that they were very impressed with the people of Bangladesh, and that they had gained a new understanding of the relationship between reproductive health and human rights.

  14. Networked innovations in guided tours

    DEFF Research Database (Denmark)

    Meged, Jane Widtfeldt; Zillinger, Malin

    The paper investigates how network innovations take place within the sharing economy based on a casestudy of free guided tour Companies in Copenhagen......The paper investigates how network innovations take place within the sharing economy based on a casestudy of free guided tour Companies in Copenhagen...

  15. A tour of inequality

    Science.gov (United States)

    Eliazar, Iddo

    2018-02-01

    This paper presents a concise and up-to-date tour to the realm of inequality indices. Originally devised for socioeconomic applications, inequality indices gauge the divergence of wealth distributions in human societies from the socioeconomic 'ground state' of perfect equality, i.e. pure communism. Inequality indices are quantitative scores that take values in the unit interval, with the zero score characterizing perfect equality. In effect, inequality indices are applicable in the context of general distributions of sizes - non-negative quantities such as count, length, area, volume, mass, energy, and duration. For general size distributions, which are omnipresent in science and engineering, inequality indices provide multi-dimensional and infinite-dimensional quantifications of the inherent inequality - i.e., the statistical heterogeneity, the non-determinism, the randomness. This paper compactly describes the insights and the practical implementation of inequality indices.

  16. Touring the Demolished Slum?

    DEFF Research Database (Denmark)

    Holst, Tore Elias Harsløf Mukherjee

    2015-01-01

    slum tourism, the article attempts to answer this question by analyzing the case of the NGO, Salaam Baalak Trust. This NGO conducted slum tours for tourists from the global North in the interstitial spaces around New Delhi Railway Station until 2010, when the slum they used as an example of their work......What are the limits of the knowledge it is ethically viable to articulate about “slums,” in a political environment where slum demolitions are a weekly occurrence? By cross-reading Partha Chatterjee's theoretical discussion of the conditions of subaltern (self)representation with studies of global...... was suddenly demolished. To the NGO staff, this posed two mutually exclusive ethical demands: a) to represent slums so that the plight of their (sometimes displaced) inhabitants might be publicized and discussed and b) to hide slums from view so the state would have no incentive to remove them as a part...

  17. The Yucca Mountain tours

    International Nuclear Information System (INIS)

    Shepard, N.F.; Champagne, D.L.

    1992-01-01

    In 1978, Mderthaner et al. observed that opposition to nuclear facilities was lowest near the facility. This suggested that opposition decreased as familiarity with the facility increased, with distance from the facility as an inverse measure of familiarity. In this paper, the authors analyze data from the literature supporting this hypothesis and examine a poll of 1200 public visitors to the candidate repository site at Yucca Mountain, Nevada, in March through June 1991. The tour poll and independent pools show that most Nevadans support the present scientific investigation of the site while opposing the repository. Among the visitors, support for the investigation increased from 66 to 90 percent, which we attribute to increased familiarity

  18. Wind tunnel evaluation of Hi-Vol TSP effectiveness data

    Data.gov (United States)

    U.S. Environmental Protection Agency — Wind tunnel evaluation of EPA's Hi-Vol TSP sampler for sampling effectiveness with regards to aerodynamic particle diameter (5 to 35 microns), wind speed (2, 8, 24...

  19. An entropy-based improved k-top scoring pairs (TSP) method for ...

    African Journals Online (AJOL)

    An entropy-based improved k-top scoring pairs (TSP) (Ik-TSP) method was presented in this study for the classification and prediction of human cancers based on gene-expression data. We compared Ik-TSP classifiers with 5 different machine learning methods and the k-TSP method based on 3 different feature selection ...

  20. 5 CFR 1601.12 - Investing future deposits in the TSP Funds.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Investing future deposits in the TSP... PARTICIPANTS' CHOICES OF TSP FUNDS Investing Future Deposits § 1601.12 Investing future deposits in the TSP.... All participants may elect to invest all or any portion of their deposits in any of the TSP Funds. [70...

  1. NEW HIGH STRENGTH AND FASTER DRILLING TSP DIAMOND CUTTERS

    Energy Technology Data Exchange (ETDEWEB)

    Robert Radtke

    2006-01-31

    The manufacture of thermally stable diamond (TSP) cutters for drill bits used in petroleum drilling requires the brazing of two dissimilar materials--TSP diamond and tungsten carbide. The ENDURUS{trademark} thermally stable diamond cutter developed by Technology International, Inc. exhibits (1) high attachment (shear) strength, exceeding 345 MPa (50,000 psi), (2) TSP diamond impact strength increased by 36%, (3) prevents TSP fracture when drilling hard rock, and (4) maintains a sharp edge when drilling hard and abrasive rock. A novel microwave brazing (MWB) method for joining dissimilar materials has been developed. A conventional braze filler metal is combined with microwave heating which minimizes thermal residual stress between materials with dissimilar coefficients of thermal expansion. The process results in preferential heating of the lower thermal expansion diamond material, thus providing the ability to match the thermal expansion of the dissimilar material pair. Methods for brazing with both conventional and exothermic braze filler metals have been developed. Finite element modeling (FEM) assisted in the fabrication of TSP cutters controllable thermal residual stress and high shear attachment strength. Further, a unique cutter design for absorbing shock, the densification of otherwise porous TSP diamond for increased mechanical strength, and diamond ion implantation for increased diamond fracture resistance resulted in successful drill bit tests.

  2. Lecturer on tour!

    Science.gov (United States)

    1998-11-01

    Readers may recall the interview with Professor Peter Kalmus which appeared in the July issue of Physics Education and which indicated his latest role of lecturer for the 1998-9 Institute of Physics Schools and Colleges Lecture series. This year's lecture is entitled `Particles and the universe' and the tour was due to begin in St Andrews, Scotland, late in September. Professor Kalmus will be looking at various aspects of particle physics, quantum physics and relativity, and discussing how they reveal the secrets of the beginning of our universe. His own experience of working at CERN, the European centre for particle physics in Switzerland, as well as at other international research facilities will provide a unique insight into activity in one of the most exciting areas of physics. The talks are aimed at the 16-19 age group but members of the public are also welcome to attend. They will act as an opportunity to gain a sneak preview of the dynamic new topics that will soon feature in the A-level syllabus arising from the Institute's 16-19 project. Further details of attendance are available from the local organizers, a list of whom may be obtained from Catherine Wilson in the Education Department at the Institute of Physics, 76 Portland Place, London W1N 3DH (tel: 0171 470 4800, fax: 0171 470 4848). The published schedule (as of September) for the lecture series consists of the following: Dates

  3. Cytotoxicity of TSP in 3D Agarose Gel Cultured Cell.

    Directory of Open Access Journals (Sweden)

    Song-I Chun

    Full Text Available A reference reagent, 3-(trimethylsilyl propionic-2, 2, 3, 3-d4 acid sodium (TSP, has been used frequently in nuclear magnetic resonance (NMR and magnetic resonance spectroscopy (MRS as an internal reference to identify cell and tissue metabolites, and determine chemical and protein structures. This reference material has been exploited for the quantitative and dynamic analyses of metabolite spectra acquired from cells. The aim of this study was to evaluate the cytotoxicity of TSP on three-dimensionally, agarose gel, cultured cells.A human osteosarcoma cell line (MG-63 was selected, and cells were three dimensionally cultured for two weeks in an agarose gel. The culture system contained a mixture of conventional culture medium and various concentrations (0, 1, 3, 5, 7, 10, 20 30 mM of TSP. A DNA quantification assay was conducted to assess cell proliferation using Quant-iT PicoGreen dsDNA reagent and kit, and cell viability was determined using a LIVE/DEAD Viability/Cytotoxicity kit. Both examinations were performed simultaneously at 1, 3, 7 and 14 days from cell seeding.In this study, the cytotoxicity of TSP in the 3D culture of MG-63 cells was evaluated by quantifying DNA (cell proliferation and cell viability. High concentrations of TSP (from 10 to 30 mM reduced both cell proliferation and viability (to 30% of the control after one week of exposure, but no such effects were found using low concentrations of TSP (0-10 mM.This study shows that low concentrations of TSP in 3D cell culture medium can be used for quantitative NMR or MRS examinations for up to two weeks post exposure.

  4. [The recent advances of HAM/TSP research].

    Science.gov (United States)

    Osame, M

    1999-12-01

    The ninth international conference on HTLVs and related disorders was held on April 5-9, 1999 at Kagoshima, Japan under the conference chairperson, Dr. Mitsuhiro Osame. In this meeting, world-wide epidemiological data on HTLV-I carriers, ATL patients, and HAM/TSP patients were summarized as shown in the table. The total number of them was supposed to be more than 2.2 millions, 1,200, and 3,000, respectively. To elucidate the localization of HTLV-I proviral DNA directly, double staining using immunohistochemistry and PCR in situ hybridization in the spinal cords of HAM/TSP patients were performed. HTLV-I proviral DNA was localized only to OPD 4-positive cells (Matsuoka et al, 1998). The localization of HTLV-I messenger RNA was the same (Moritoyo et al, 1996). A novel technique to detect HTLV-I tax protein was also developed. In HAM/TSP patients, 0.04-1.16% of the CSF cells and 0.02-0.54% of PBMCs were positive for HTLV-I tax protein (Moritoyo et al, 1999). It was also hypothesized that HLA alleles control HTLV-I proviral load and thus influence susceptibility to HAM/TSP. Two hundred and thirty-two cases of HAM/TSP were compared with 201 randomly selected HTLV-I seropositive asymptomatic blood donors. It was shown that, after infection with HTLV-I, the class I allele HLA-A*02 halves the odds of HAM/TSP (p doubled the odds of HAM/TSP in the absence of the protective effect of HLA-A*02 (Jeffery and Usuku et al, 1999).

  5. Barents Tour for Geotourists

    Science.gov (United States)

    Pihlaja, Jouni; Johansson, Peter; Lauri, Laura

    2015-04-01

    Barents Tour for Geotourists is a guidebook for a circular route locating in northern Finland, northern Norway and north-western Russia. The targets along the route are all connected with different aspects of geology: there are localities presenting rare rock types and minerals, potholes, gorges, eskers, raised beaches and palsa mires. Total number of sites along the route is 26, 14 of them are locating in Finland, 4 in Norway and 8 in the Kola Peninsula, Russia. In addition to geological information on the sites, the guidebook features directions and information on local tourism services in four languages: English, Finnish, Russian and Norwegian. Good examples of the geological sites in northern Finland are the potholes at Aholanvaara, Salla. The largest pothole is called the "Drinking pot". With a diameter of 15.5 m and a depth of 9.5 m it is the largest known pothole in Finland. One famous target in northern Finland is also the Gold Prospector Museum and geological nature trail at Tankavaara, Sodankylä. The museum has an impressive mineral and jewellery stone collection and it is the only international museum in the world displaying past and present items of gold panning and prospecting. The Khibiny Tundra is the largest mountain massif on the Kola Peninsula, Russia. These mountains are best known for their unique landscapes, geology and mineralogy. With an experienced guide, minerals like apatite, nepheline, titanite, eudialyte and lamprophyllite can be found there. In north-eastern Norway, the palsas at Øvre Neiden and Færdesmyra are examples of a specific mire type in the cold climate area. The palsa mires are characterized by the presence of 2-5 m high peat mounds that consist of interleaved peat and ice layers. The route was planned and implemented in the ABCGheritage project (Arctic Biological, Cultural and Geological Heritage) partly funded by the Kolarctic ENPI CBC program of the European Union. The guidebook was written by researchers of the

  6. CD Review: Tour de Force

    Directory of Open Access Journals (Sweden)

    Diana Golden

    2016-10-01

    Full Text Available Review of Tour de Force, the third album from C Force, an ensemble comprised of flutist Christine Gangelhoff, euphoniumist Christian Justilien, and pianist Christy Lee. With repertoire spanning over two centuries, the trio embarks on a musical tour to Guadaloupe, Jamaica, and Haiti on Disc One, and then Trinidad and Tobago, Curaçao, the U.S. Virgin Islands and the Bahamas on Disc Two. Just as the eclectic album artwork by John Cox might suggest, Tour de Force provides listeners with a sense of the rich tapestry of musical connections shared in art music across the Caribbean. This two-disc set (released March 2016 was recorded at the Performing Arts Center of The College of The Bahamas and produced by Terry Manning of Lucky Seven Records.

  7. : Virtual Tours in School Context

    Directory of Open Access Journals (Sweden)

    Nuno Ribeiro,

    2016-12-01

    Full Text Available This article is based on the importance of using virtual tours in schools as a means to disseminate local cultural heritage, school projects and teaching resources. We want to use virtual tours, involving the school community in its use, through the production of relevant multimedia content as a way to understand and analyze the potential of multimedia resources in schools. With the evolution of new technologies, including the internet, it is up to the schools, as sources of knowledge transmission, to resort to new technologies as a way to encourage students to learn, to promote local heritage and to disclose the work of the school community, using virtual tours in school context as a powerful interdisciplinary technical and educational resource.

  8. Networked innovations in guided tours

    DEFF Research Database (Denmark)

    Meged, Jane Widtfeldt; Zillinger, Malin

    This presentation is about a case study being done on networked innovation that is taking place within the scene of free guided tours in Copenhagen. Data has been collected on interactions between actors within the network of peers. In this way, both the own organisation and the actual market...... is being continually developed. ICT plays a key role, just as well as the relationships between the individual actors. It has been shown that close relationships building on friendship and trust are beneficial for the process of innovation. The fast growth of the sector of free guided tours however poses...

  9. How to Arrange Student Tours to the Soviet Union.

    Science.gov (United States)

    Winokur, Marshall

    The details of planning a student tour to the Soviet Union are described by an experienced tour organizer. Student tours of one to three weeks are presented as rewarding alternatives to lengthy overseas study. Recommendations are made regarding choice of tour type, length of tour, travel agencies, time of year to travel, advertising a tour,…

  10. Learning and Personality on Study Tours Abroad

    Science.gov (United States)

    Miao, Shin Yu; Harris, Roger

    2012-01-01

    Study tours abroad are important arenas for post-compulsory education. This paper focuses on how personality affects students' learning on study tours abroad. The research involved 66 learners from one higher education institution in Taiwan on tours to the UK, the USA and Australia. Data were gathered using questionnaires and learning journals,…

  11. Library Virtual Tours: A Case Study

    Science.gov (United States)

    Ashmore, Beth; Grogg, Jill E.

    2004-01-01

    Virtual tours delivered via the Web have become a common tool for both instruction and outreach. This article is a case study of the creation of a virtual tour for a university library and is intended to provide others interested in creating a virtual tour of their library the opportunity to learn from the mistakes and successes of fellow…

  12. Tour Guiding Research Insights, Issues and Implications

    DEFF Research Database (Denmark)

    Meged, Jane Widtfeldt

    2017-01-01

    The book Tour guiding research – insights, issues and implications by Betty Weiler and Rosemary Black is a most welcome contribution to the specific research field of guided tours within tourism studies. It sets forth to “give an authoritative state-of-art review of the scholarly literature on tour...

  13. The Effects of the Mediation and Leadership Role of Tour Guides on the Tour Experience: A Research on Nature Tours

    Directory of Open Access Journals (Sweden)

    F Özlem GÜZEL

    2014-12-01

    Full Text Available Other than being a profession that extends beyond only providing information on the historical monuments, tour guiding is a job that has positive effects on the holistic holiday experience. Thus, this profession in its context embodies many different roles that are necessary. With this context, the purpose of this study is primarily to analyze the effects of the leadership and mediation roles on certificated tour guide performance evaluation and then on holistic tour experience. Consequently, in order to determine the relationships between parameters, a field survey at Sarigerme tourism region was conducted on the guided nature tours during the months of May, June and July in 2013. Through the data obtained by the questionnaires, the relationship between the leadership role / mediator role of tour guides on tour guides‟ performance and holistic tour experience basing on two different models was analyzed with Structural Equation Method (SEM. As an outcome of the survey, it was found that the leadership role/mediator role of tour guides on the evaluation of the tour guides‟ performance and that the tour guide performance has positive effects on the evaluation holistic tour experience

  14. Team Software Process (TSP) Coach Mentoring Program Guidebook

    Science.gov (United States)

    2009-08-01

    Hodgins, Michelle Jurkouich, Delwyn Kel- logg, Juan Lopez, Andy Oughton, Rafael Salazar, and Jim Van Buren. vi | CMU/SEI-2009-SR-009 1...listed below in bold font ) are areas that should be of particular interest for potential SEI-Certified TSP Coaches and Mentor Coaches, as these are

  15. Fractionation of applied 32P labeled TSP in calcareous soils

    International Nuclear Information System (INIS)

    Asfary, A.F.; Al-Merey, R.; Al-Hameish, M.

    2005-01-01

    Calcareous dark brown red soil (calcixerollic xerochrept) from northern Syria was used in a pot experiment to study the fate of triple super phosphate fertilizer (TSP) with and without a crop (Local durum wheat (Triticum turgidum L. group durum (Desf)) c v. Bohouth). The soil received 17μg P/g soil of 32 P labeled TSP, and samples were collected from soils and plants at successive dates. Soil inorganic P was ≅94% of total soil P, with only 50-80% being soluble. Calcium phosphate compounds were the dominant fraction (≤68%) of the soluble inorganic soil P followed by occluded iron phosphate (≤48%) and all other fractions were ≤9%. Isotopic measurements showed that ≅ 50% of fertilizer P was nonexchangeable within 2 days, and TSP values in each fraction of soil inorganic P fluctuated in relatively similar proportions to the concentrations of fractions in soil. Available P (soil and TSP) in cropped soil was more than that in the uncropped soil, and plants had no effect on the distribution of P from fertilizer amongst the different P fractions. (author)

  16. Google Earth Grand Tour Themes

    Science.gov (United States)

    De Paor, D. G.; Whitmeyer, S. J.; Bentley, C.; Dordevic, M. M.

    2014-12-01

    As part of an NSF TUES Type 3 project entitled "Google Earth for Onsite and Distance Education (GEODE)," we are assembling a "Grand Tour" of locations on Earth and other terrestrial bodies that every geoscience student should know about and visit at least in virtual reality. Based on feedback from colleagues at previous meetings, we have identified nine Grand Tour themes: "Plates and Plumes," "Rocks and Regions," "Geology Through Time," "The Mapping Challenge*," "U.S. National Parks*," "The Magical Mystery Tour*," "Resources and Hazards," "Planets and Moons," and "Top of the Pops." Themes marked with an asterisk are most developed at this stage and will be demonstrated in real time. The Mapping Challenge invites students to trace geological contacts, measure bedding strike and dip and the plunge, trend, and facing of a fold. There is an advanced tool for modeling periclinal folds. The challenge is presented in a game-like format with an emphasis on puzzle-solving that will appeal to students regardless of gender. For the tour of U.S. national parks, we divided the most geologically important parks into four groups—Western Pacific, West Coast, Rockies, and East Coast. We are combining our own team's GigaPan imagery with imagery already available on the Internet. There is a great deal of imagery just waiting to be annotated for geological education purposes. The Magical Mystery Tour takes students to Google Streetview locations selected by instructors. Students are presented with questions or tasks and are given automatic feedback. Other themes are under development. Within each theme, we are crowd-sourcing contributions from colleagues and inviting colleagues to vote for or against proposed locations and student interactions. The GEODE team includes the authors and: Heather Almquist, Stephen Burgin, Cinzia Cervato, Gene Cooper, Paul Karabinos, Terry Pavlis, Jen Piatek, Bill Richards, Jeff Ryan, Ron Schott, Kristen St. John, and Barb Tewksbury.

  17. A Bibliography of the Personal Software Process (PSP) and the Team Software Process (TSP)

    Science.gov (United States)

    2009-10-01

    tspsymposium/ Padula , Alan. ―TSP-Agile Showdown: The Gun Smoke Clears.‖ Proceedings of the TSP Sympo- sium (September 2009). http://www.sei.cmu.edu...www.sei.cmu.edu/tspsymposium/ Padula , Alan. ―TSP—Agile Showdown.‖ Proceedings of the TSP Symposium (September 2008). http://www.sei.cmu.edu

  18. A tour in sign language

    CERN Document Server

    François Briard

    2016-01-01

    In early May, CERN welcomed a group of deaf children for a tour of Microcosm and a Fun with Physics demonstration.   On 4 May, around ten children from the Centre pour enfants sourds de Montbrillant (Montbrillant Centre for Deaf Children), a public school funded by the Office médico-pédagogique du canton de Genève, took a guided tour of the Microcosm exhibition and were treated to a Fun with Physics demonstration. The tour guides’ explanations were interpreted into sign language in real time by a professional interpreter who accompanied the children, and the pace and content were adapted to maximise the interaction with the children. This visit demonstrates CERN’s commitment to remaining as widely accessible as possible. To this end, most of CERN’s visit sites offer reduced-mobility access. In the past few months, CERN has also welcomed children suffering from xeroderma pigmentosum (a genetic disorder causing extreme sensiti...

  19. Enhanced protective efficacy of a chimeric form of the schistosomiasis vaccine antigen Sm-TSP-2.

    Directory of Open Access Journals (Sweden)

    Mark S Pearson

    Full Text Available The large extracellular loop of the Schistosoma mansoni tetraspanin, Sm-TSP-2, when fused to a thioredoxin partner and formulated with Freund's adjuvants, has been shown to be an efficacious vaccine against murine schistosomiasis. Moreover, Sm-TSP-2 is uniquely recognised by IgG(1 and IgG(3 from putatively resistant individuals resident in S. mansoni endemic areas in Brazil. In the present study, we expressed Sm-TSP-2 at high yield and in soluble form in E. coli without the need for a solubility enhancing fusion partner. We also expressed in E. coli a chimera called Sm-TSP-2/5B, which consisted of Sm-TSP-2 fused to the immunogenic 5B region of the hookworm aspartic protease and vaccine antigen, Na-APR-1. Sm-TSP-2 formulated with alum/CpG showed significant reductions in adult worm and liver egg burdens in two separate murine schistosomiasis challenge studies. Sm-TSP-2/5B afforded significantly greater protection than Sm-TSP-2 alone when both antigens were formulated with alum/CpG. The enhanced protection obtained with the chimeric fusion protein was associated with increased production of anti-Sm-TSP-2 antibodies and IL-4, IL-10 and IFN-γ from spleen cells of vaccinated animals. Sera from 666 individuals from Brazil who were infected with S. mansoni were screened for potentially deleterious IgE responses to Sm-TSP-2. Anti-Sm-TSP-2 IgE to this protein was not detected (also shown previously for Na-APR-1, suggesting that the chimeric antigen Sm-TSP-2/5B could be used to safely and effectively vaccinate people in areas where schistosomes and hookworms are endemic.

  20. NORPERM, the Norwegian Permafrost Database - a TSP NORWAY IPY legacy

    Science.gov (United States)

    Juliussen, H.; Christiansen, H. H.; Strand, G. S.; Iversen, S.; Midttømme, K.; Rønning, J. S.

    2010-10-01

    NORPERM, the Norwegian Permafrost Database, was developed at the Geological Survey of Norway during the International Polar Year (IPY) 2007-2009 as the main data legacy of the IPY research project Permafrost Observatory Project: A Contribution to the Thermal State of Permafrost in Norway and Svalbard (TSP NORWAY). Its structural and technical design is described in this paper along with the ground temperature data infrastructure in Norway and Svalbard, focussing on the TSP NORWAY permafrost observatory installations in the North Scandinavian Permafrost Observatory and Nordenskiöld Land Permafrost Observatory, being the primary data providers of NORPERM. Further developments of the database, possibly towards a regional database for the Nordic area, are also discussed. The purpose of NORPERM is to store ground temperature data safely and in a standard format for use in future research. The IPY data policy of open, free, full and timely release of IPY data is followed, and the borehole metadata description follows the Global Terrestrial Network for Permafrost (GTN-P) standard. NORPERM is purely a temperature database, and the data is stored in a relation database management system and made publically available online through a map-based graphical user interface. The datasets include temperature time series from various depths in boreholes and from the air, snow cover, ground-surface or upper ground layer recorded by miniature temperature data-loggers, and temperature profiles with depth in boreholes obtained by occasional manual logging. All the temperature data from the TSP NORWAY research project is included in the database, totalling 32 temperature time series from boreholes, 98 time series of micrometeorological temperature conditions, and 6 temperature depth profiles obtained by manual logging in boreholes. The database content will gradually increase as data from previous and future projects are added. Links to near real-time permafrost temperatures, obtained

  1. Study tour in Russia at harvesting time

    International Nuclear Information System (INIS)

    1972-01-01

    A unique study tour on the use of isotopes and radiation in genetics and plant breeding was recently held in the USSR. It was the 11th in the series of the Agency's Study Tour Programme for scientists from developing countries, the principles of which were outlined in Bulletin Volume 13, No. 3, 1971. Eight study tours were organised from 1966 to 1971. This year three further tours have been conducted: the 9th on radiological protection in CSSR, Sweden, the Federal Republic of Germany and USSR, the 10th on the mass rearing of insects as related to the sterile male technique in the USA, and the latest again in the USSR. Included are some notes on the programme and participation of this tour. (author)

  2. Advanced evaluation method of SG TSP BEC hole blockage rate

    International Nuclear Information System (INIS)

    Izumida, Hiroyuki; Nagata, Yasuyuki; Harada, Yutaka; Murakami, Ryuji

    2003-01-01

    In spite of the control of the water chemistry of SG secondary feed-water in PWR-SG, SG TSP BEC holes, which are the flow path of secondary water, are often clogged. In the past, the trending of BEC hole blockage rate has conducted by evaluating ECT original signals and visual inspections. However, the ECT original signals of deposits are diversified, it becomes difficult to analyze them with the existing evaluation method using the ECT original signals. In this regard, we have developed the secondary side visual inspection system, which enables the high-accuracy evaluation of BEC hole blockage rate, and new ECT signal evaluation method. (author)

  3. A review of tsp as one of the transportation security aspects of nuclear materials

    International Nuclear Information System (INIS)

    Wiryono

    2013-01-01

    A review has done for the Transportation Safety Plan (TSP) as one of the aspects of safety in the transport of nuclear materials. The review is necessary to harmonize national regulations with international practice. International practice of using TSP as one of the security requirements in addition to the Radiation Protection Program as a requirement of safety in the transport of nuclear materials. TSP is intended to ensure sound implementation of the transport of nuclear materials. TSP evaluation process can be done with a prescriptive approach, performance, and combinations. TSP contains information about administrative requirements, delivery security and response planning. TSP can be used to ensure the security of the implementation of the transport of nuclear materials effectively and efficiently. BAPETEN should require the applicant to submit the TSP as one document security requirements prior approval transporting nuclear materials. BAPETEN need to define the approach to the formulation and evaluation of TSP. BAPETEN need to set up an evaluation and inspection procedures for the implementation of TSP. (author)

  4. A Discrete Fruit Fly Optimization Algorithm for the Traveling Salesman Problem.

    Directory of Open Access Journals (Sweden)

    Zi-Bin Jiang

    Full Text Available The fruit fly optimization algorithm (FOA is a newly developed bio-inspired algorithm. The continuous variant version of FOA has been proven to be a powerful evolutionary approach to determining the optima of a numerical function on a continuous definition domain. In this study, a discrete FOA (DFOA is developed and applied to the traveling salesman problem (TSP, a common combinatorial problem. In the DFOA, the TSP tour is represented by an ordering of city indices, and the bio-inspired meta-heuristic search processes are executed with two elaborately designed main procedures: the smelling and tasting processes. In the smelling process, an effective crossover operator is used by the fruit fly group to search for the neighbors of the best-known swarm location. During the tasting process, an edge intersection elimination (EXE operator is designed to improve the neighbors of the non-optimum food location in order to enhance the exploration performance of the DFOA. In addition, benchmark instances from the TSPLIB are classified in order to test the searching ability of the proposed algorithm. Furthermore, the effectiveness of the proposed DFOA is compared to that of other meta-heuristic algorithms. The results indicate that the proposed DFOA can be effectively used to solve TSPs, especially large-scale problems.

  5. ETH Zurich tour at CERN.

    CERN Multimedia

    Maximilien Brice

    2002-01-01

    Right to left: Thomas Wobmann and Markus Zemp visit the LHC tunnel at CERN with G nther Dissertori and Marcel Wyler of ETH Zurich. Their visit was part of the top prize for a competition organised by the ETH department of physics to coincide with its open day in June. Residents of Zurich and surrounding Swiss cantons were invited to answer five physics questions broadcast on local radio and the Internet the week before the open day. The two winners' reward for knowing who did not believe that God plays dice, among other things, was a flight offered by Swiss International Air Lines to Geneva and a VIP tour of CERN. One highlight was a trip to the underground site of the future CMS experiment, where the scale of the enormous cavern makes construction machines look like children's toys.

  6. Tour operators, environment and sustainable development

    International Nuclear Information System (INIS)

    Andriola, L.; Chirico, R.; Declich, P.

    2001-01-01

    The purpose of this work is to characterize the role of the tour operators in achieving sustainable development meaning a process of development which leaves at least the same amount of capital, natural and man-made, to future generations as current generations have access to. Tourism is one of the largest and fastest growing global industries, creating significant employment and economic development, particularly in many developing countries. Tourism can also have negative environmental and social impact resulting from resource consumption, pollution, generation of wastes and from the compromise of local culture while introducing new activities. Most tour operators has started to recognised that a clean environment is critical to their success, but few tour operators have the management tools or experience to design and conduct tours that minimize their negative environmental and social impacts. A group of tour operators from different parts of the world have joined forces to create the Tour Operators' Initiative for Sustainable Tourism Development. With this initiatives, tour operators are moving towards sustainable tourism by committing themselves to address the environmental, social, and cultural aspects of sustainable development within the tourism sector [it

  7. Tourists Co-producing Guided Tours

    DEFF Research Database (Denmark)

    Larsen, Jonas; Meged, Jane Widtfeldt

    2013-01-01

    The guided tour is a stigmatized tourist practice. In contrast to studies portraying sightseeing tours as an over-determined stage where tourists passively follow prescripted routes and scripts, this article also uncovers creativity, detours and productive practices. We examine how tourists can...... discussion of some of Goffman's central concepts. Second, we move on to a more general discussion of how front-stage tourism services are performances where both tourist staff and guests play their part. Third, we examine ethnographically how participants on guided tours in Copenhagen co...

  8. Economic tour package model using heuristic

    Science.gov (United States)

    Rahman, Syariza Abdul; Benjamin, Aida Mauziah; Bakar, Engku Muhammad Nazri Engku Abu

    2014-07-01

    A tour-package is a prearranged tour that includes products and services such as food, activities, accommodation, and transportation, which are sold at a single price. Since the competitiveness within tourism industry is very high, many of the tour agents try to provide attractive tour-packages in order to meet tourist satisfaction as much as possible. Some of the criteria that are considered by the tourist are the number of places to be visited and the cost of the tour-packages. Previous studies indicate that tourists tend to choose economical tour-packages and aiming to visit as many places as they can cover. Thus, this study proposed tour-package model using heuristic approach. The aim is to find economical tour-packages and at the same time to propose as many places as possible to be visited by tourist in a given geographical area particularly in Langkawi Island. The proposed model considers only one starting point where the tour starts and ends at an identified hotel. This study covers 31 most attractive places in Langkawi Island from various categories of tourist attractions. Besides, the allocation of period for lunch and dinner are included in the proposed itineraries where it covers 11 popular restaurants around Langkawi Island. In developing the itinerary, the proposed heuristic approach considers time window for each site (hotel/restaurant/place) so that it represents real world implementation. We present three itineraries with different time constraints (1-day, 2-day and 3-day tour-package). The aim of economic model is to minimize the tour-package cost as much as possible by considering entrance fee of each visited place. We compare the proposed model with our uneconomic model from our previous study. The uneconomic model has no limitation to the cost with the aim to maximize the number of places to be visited. Comparison between the uneconomic and economic itinerary has shown that the proposed model have successfully achieved the objective that

  9. Plant inspection tours with mobile data logging system

    International Nuclear Information System (INIS)

    Roesser, U.

    2006-01-01

    The MDE Mobile Data Logging System has been introduced in a number of German power plants for efficient logging, evaluation, and quality-assured documentation of data recorded on plant inspection tours by means of pocket PCs instead of slips of paper. It will be installed in other nuclear power plants in the near future. The MDE system is composed of the pocket PCs for logging data during plant inspection tours, the associated docking stations installed in the respective areas of application, one PC or, if necessary, several PCs with the appropriate user software, and the associated network links. To install the software in the power plant, lists of rooms and measurement stations as well as other positions on an inspection course are transmitted to the MDE system. When the system has been commissioned, inspection tours are planned in accordance with past experience and optimized in the computer. User experience is taken into account in program updates. New functions improve user comfort and ease of evaluation. Additions to the MDE software, and applications in other areas, are tentatively planned and will be implemented as the need arises. (orig.)

  10. General k-opt submoves for the Lin-Kernighan TSP heuristic

    DEFF Research Database (Denmark)

    Helsgaun, Keld

    2009-01-01

    Local search with k-exchange neighborhoods, k-opt, is the most widely used heuristic method for the traveling salesman problem (TSP). This paper presents an effective implementation of k-opt in LKH-2, a variant of the Lin–Kernighan TSP heuristic. The effectiveness of the implementation...

  11. An Effective Implementation of K-opt Moves for the Lin-Kernighan TSP Heuristic

    DEFF Research Database (Denmark)

    Helsgaun, Keld

    Local search with k-change neighborhoods, k-opt, is the most widely used heuristic method for the traveling salesman problem (TSP). This report presents an effective implementation of k-opt for the Lin- Kernighan TSP heuristic. The effectiveness of the implementation is demonstrated with extensive...

  12. 41 CFR 102-117.280 - What aspects of the TSP's performance are important to measure?

    Science.gov (United States)

    2010-07-01

    ...'s performance are important to measure? 102-117.280 Section 102-117.280 Public Contracts and... § 102-117.280 What aspects of the TSP's performance are important to measure? Important TSP performance...) Percentage of customer satisfaction reports on carrier performance. ...

  13. KANDUNGAN TSP DAN PM-10 DI UDARA JAKARTA DAN SEKITARNYA

    Directory of Open Access Journals (Sweden)

    Hendro Martono

    2016-09-01

    Full Text Available Abstract. A survey was performed to assess the quality of ambient air in Jakarta, Bogor,Depok,  Tangerang  and Bekasi.  Ambient air samples were collected from 33 sampling points at a distance of 0meter and 120 meters from each main roads respectively. The highest average content of TSP in ambientair at 0 meter was found in West Jakarta (652.02 p.g/cu.m and that of 120 meters from the main road was in Bekasi (445.46µg/cu.m . The highest difference of the TSP content between the two sampling pointswas in Kebon  Jeruk, West Jakarta (96.62 %,  and the lowest one was inCikarang, Bekasi (1.63 %.  Furthermore, the highest difference of the PM-10 content between the two sampling points was inJalan  Raya Bogor, Depok  (96.86 %,  and the lowest one was in Cikarang,  Bekasi (17.26%. In the whole areasof study, the average content of TSP  was 522.44.tg/cu.m  (0 meter, and178.09µg/cu.m (120 meters,  so the difference of the pollutant content between the two sampling points was 65.91%. Meanwhile, theaverage content of PM-10 was 326.25µg/cu.m  (0 meter, and97.09µg/cu.m (120 meters, so the difference of the pollutant content between the two sampling points was 70.24 %. The difference of the means ofboth TSP  and PM-10 content levels between the two sampling sites were significant. The percentages ofsampling points complying withTSP level standard were 9.52 %  (0 meter and 75.76% (120 meters from the road sides. While that of PM-10 were 18.18%  (road side sampling and 78.79% (120 meters from theroad sides.Crusial  measure for controlling theTSP  and PM-10 pollution should also be addressed tomobile sources, such as reducing diesel motorized-vehicles and providing proper mass transportation.

  14. A whistle-stop tour of statistics

    National Research Council Canada - National Science Library

    Everitt, Brian

    2012-01-01

    "Preface according to my Penguin English dictionary, whistle-stop, used before a noun means 'consisting of brief stops in several places' and this whistle-stop tour of statistics does just that, with...

  15. Tour of the Standards and Calibrations Laboratory

    International Nuclear Information System (INIS)

    Elliott, J.H.

    1978-01-01

    This tour of Lawrence Livermore Laboratory's Standards and Calibrations Laboratory is intended as a guide to the capabilities of and services offered by this unique laboratory. Described are the Laboratory's ability to provide radiation fields and measurements for dosimeters, survey instruments, spectrometers, and sources and its available equipment and facilities. The tour also includes a survey of some Health Physics and interdepartmental programs supported by the Standards and Calibrations Laboratory and a listing of applicable publications

  16. NEWS ABOUT HOPITAL DE LA TOUR

    CERN Multimedia

    Sylvain Weisz

    2002-01-01

    Mr. James Bissell, Director of the Hôpital de La Tour, has directly circulated the medical practitioners in the area and some of you with a letter setting out to defend the financial interests of his establishment. This initiative, which was taken without consulting us, is designed to sow confusion about the scale of La Tour price rises and the unequal treatment we are receiving, as compared with individuals insured with Swiss health insurance firms. In fact, the letter from La Tour (published on our site) casts doubt on our statements in the CHIS Bull' No. 12, which we reassert here, viz., the average increase in rates that La Tour charges CERN Members is 15%; the discounts that we have been able to negotiate with the Cantonal Hospital and other private hospital institutions in Geneva such as the Clinique Générale Beaulieu constitute savings of 20 to 40% by comparison with rates charged at La Tour; for outpatient care, La Tour does not charge the same rates to Members of the CHIS as it does to those b...

  17. The threonine protease activity of testes-specific protease 50 (TSP50 is essential for its function in cell proliferation.

    Directory of Open Access Journals (Sweden)

    Yu-Yin Li

    Full Text Available BACKGROUND: Testes-specific protease 50 (TSP50, a newly discovered threonine enzyme, has similar amino acid sequences and enzymatic structures to those of many serine proteases. It may be an oncogene. TSP50 is up-regulated in breast cancer epithelial cells, and ectopic expression of TSP50 in TSP50-deficient Chinese hamster ovary (CHO cells has been found to promote cell proliferation. However, the mechanisms by which TSP50 exerts its growth-promoting effects are not yet fully understood. METHODOLOGY/PRINCIPAL FINDINGS: To delineate whether the threonine protease activity of TSP50 is essential to its function in cell proliferation, we constructed and characterized a mutant TSP50, called TSP50 T310A, which was identified as a protease-dead mutant of TSP50. By a series of proliferation analyses, colony formation assays and apoptosis analyses, we showed that T310A mutation significantly depresses TSP50-induced cell proliferation in vitro. Next, the CHO stable cell line expressing either wild-type or T310A mutant TSP50 was injected subcutaneously into nude mice. We found that the T310A mutation could abolish the tumorigenicity of TSP50 in vivo. A mechanism investigation revealed that the T310A mutation prevented interaction between TSP50 and the NF-κBIκBα complex, which is necessary for TSP50 to perform its function in cell proliferation. CONCLUSION: Our data highlight the importance of threonine 310, the most critical protease catalytic site in TSP50, to TSP50-induced cell proliferation and tumor formation.

  18. 41 CFR 102-117.255 - What actions may I take if the TSP's performance is not satisfactory?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What actions may I take if the TSP's performance is not satisfactory? 102-117.255 Section 102-117.255 Public Contracts and... may I take if the TSP's performance is not satisfactory? If the TSP's performance is not satisfactory...

  19. 41 CFR 102-117.285 - What are my choices if a TSP's performance is not satisfactory?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What are my choices if a TSP's performance is not satisfactory? 102-117.285 Section 102-117.285 Public Contracts and Property... are my choices if a TSP's performance is not satisfactory? You may choose to place a TSP in temporary...

  20. Binary Cockroach Swarm Optimization for Combinatorial Optimization Problem

    Directory of Open Access Journals (Sweden)

    Ibidun Christiana Obagbuwa

    2016-09-01

    Full Text Available The Cockroach Swarm Optimization (CSO algorithm is inspired by cockroach social behavior. It is a simple and efficient meta-heuristic algorithm and has been applied to solve global optimization problems successfully. The original CSO algorithm and its variants operate mainly in continuous search space and cannot solve binary-coded optimization problems directly. Many optimization problems have their decision variables in binary. Binary Cockroach Swarm Optimization (BCSO is proposed in this paper to tackle such problems and was evaluated on the popular Traveling Salesman Problem (TSP, which is considered to be an NP-hard Combinatorial Optimization Problem (COP. A transfer function was employed to map a continuous search space CSO to binary search space. The performance of the proposed algorithm was tested firstly on benchmark functions through simulation studies and compared with the performance of existing binary particle swarm optimization and continuous space versions of CSO. The proposed BCSO was adapted to TSP and applied to a set of benchmark instances of symmetric TSP from the TSP library. The results of the proposed Binary Cockroach Swarm Optimization (BCSO algorithm on TSP were compared to other meta-heuristic algorithms.

  1. Touring by Design: Using Information Architecture To Create a Virtual Library Tour.

    Science.gov (United States)

    Kittelson, Pat; Jones, Sarah

    2002-01-01

    Describes the development of a Web-based virtual tour of the University of Otago (New Zealand) science library. Highlights include information literacy learning outcomes; information architecture, including information organization and navigation; integrating the tour into course work; and evaluation results. (LRW)

  2. Next step, the Tour de France?

    CERN Multimedia

    Anaïs Schaeffer

    2013-01-01

    The penultimate stage of the 2013 Tour de France, the Annecy-Semnoz time-trial, has already been won – by a CERN staff member!     In keeping with tradition, the organisers of the Tour de France organise another race, the Étape du Tour, which is open to the general public and follows the actual route of an official stage of the Tour proper. This year, the chosen venue was Annecy and its neighbouring mountain, Le Semnoz, which played host to 11,000 cycling enthusiasts from all parts. This penultimate stage of the 2013 Tour will be raced by the professionals on 20 July. The public race was won by Nicolas Roux, an experienced cyclist and member of CERN’s GS-IS Group, who devoured the 128-km course in just 4 hours and 15 minutes, nine seconds ahead of cycling champion Julien Absalon. “I just managed to overhaul Julien Absalon 500 m before the finishing line,” Nicolas recounts. “It was a fantastic race!” Come rain o...

  3. An entropy-based improved k-top scoring pairs (TSP) method for ...

    African Journals Online (AJOL)

    DR. NJ TONUKARI

    2012-06-05

    Jun 5, 2012 ... Key words: Cancer classification, gene expression, k-TSP, information entropy, gene selection. INTRODUCTION ..... The 88 kDa precursor protein, progranulin, is also ... TCF3 is in acute myeloid leukemia pathway, so it is.

  4. Pumping characteristics of sputter ion pump (SIP) and titanium sublimation pump (TSP) combination

    International Nuclear Information System (INIS)

    Ratnakala, K.C.; Patel, R.J.; Bhavsar, S.T.; Pandiyar, M.L.; Ramamurthi, S.S.

    1995-01-01

    For achieving hydrocarbon free, clean ultra high vacuum, SIP-TSP combination is one of the ideal choice for pumping. For the SRS facility in Centre for Advanced Technology (CAT), we are utilising this combination, enmass. For this purpose, two modules of these combination set-ups are assembled, one with the TSP as an integral part of SIP and the other, with TSP as a separate pump mounted on the top of SIP. The pump bodies were vacuum degassed at 700 degC at 10 -5 mbar for 3 hrs. An ultimate vacuum of 3 x 10 -11 mbar was achieved, after a bake-out at 250 degC for 4 hrs, followed by continuous SIP pumping for 48 hrs, with two TSP flashing at approximately 10 hrs interval. The pump-down patterns as well as the pressure-rise patterns are studied. (author). 2 refs., 5 figs

  5. A Unified Grand Tour of Theoretical Physics

    CERN Document Server

    Lawrie, Ian D

    2002-01-01

    A unified account of the principles of theoretical physics, A Unified Grand Tour of Theoretical Physics, Second Edition stresses the inter-relationships between areas that are usually treated as independent. The profound unifying influence of geometrical ideas, the powerful formal similarities between statistical mechanics and quantum field theory, and the ubiquitous role of symmetries in determining the essential structure of physical theories are emphasized throughout.This second edition conducts a grand tour of the fundamental theories that shape our modern understanding of the physical wor

  6. Developing a Canoe Tour for Upitrek Ltd.

    OpenAIRE

    Matzner, Ute

    2011-01-01

    The thesis was aimed to result in a sound paddling tourism product for the tour operator Upitrek Ltd. This request of product extension was based on the customer demands the company is facing. Therefore Upitrek Ltd. has acted as the commissioning party in this thesis, as the company will be provided with a fully developed tour product. The first section of this work investigates the history and current situation of the sector of water-based tourism, with an emphasis on paddling tourism, b...

  7. A Metro Map Metaphor for Guided Tours on the Web

    DEFF Research Database (Denmark)

    Sandvad, Elmer Sørensen; Grønbæk, Kaj; Sloth, Lennert

    2001-01-01

    maps and route maps with indication of which stations of a tour have been visited; and finally (4) support for arbitrary web pages as stations on the tour. The paper discusses the Webvise Guided Tour System and illustrates its use in a digital library portal. The system is compared to other recent Web......This paper presents a guided tour system for the WWW. It is a module for the Webvise open hypermedia system that implements the ideas of trails and guided tours, originating from the hypertext field. Webvise appears as an open hypermedia helper application to the user and stores the guided tours...... in an XML format called OHIF separated from the WWW documents included in the tour. The main advantages of the system are: (1) a browser independent format in terms of HTML and PNG-based image maps for reading the guided tours; (2) support for a familiar metaphor, namely, a metro route map; (3) overview...

  8. Cultural Tourism Tours and Main Routes Towards Turkey

    Directory of Open Access Journals (Sweden)

    Veysi GÜNAL

    2009-06-01

    Full Text Available Today, the tourism has become a important industry. Certainly, the most important international actors af this industry are tour operators. The tour operators which realize about 75 percent of the total tourism activity to Turkey have taken a very important mission from the point of Turkey tourism. The, Germany, Netherlands, England and USA tour operators, which have made the important part of the tours to our country, have also an important position in organizating cultural tour. When the cultural tours, which have been planned to Turkey by this countries, have been studied it is seen that these tours have containied more mass tourism areas or near areas of these region. It can be said that Turkey’s not marketing its tourism correctly has be effective in this subject. With this research, it has been studied how the cultural attractions in Turkey have been perceived, consumed and marketed by abroad tour operators.

  9. Tour operators, environment and sustainable development; Tour operator, ambiente e sviluppo sostenibile

    Energy Technology Data Exchange (ETDEWEB)

    Andriola, L.; Chirico, R.; Declich, P. [ENEA, Divisione Caratterizzazione dell' Ambiente e del Territorio, Centro Ricerche Casaccia, Rome (Italy)

    2001-07-01

    The purpose of this work is to characterize the role of the tour operators in achieving sustainable development meaning a process of development which leaves at least the same amount of capital, natural and man-made, to future generations as current generations have access to. Tourism is one of the largest and fastest growing global industries, creating significant employment and economic development, particularly in many developing countries. Tourism can also have negative environmental and social impact resulting from resource consumption, pollution, generation of wastes and from the compromise of local culture while introducing new activities. Most tour operators has started to recognised that a clean environment is critical to their success, but few tour operators have the management tools or experience to design and conduct tours that minimize their negative environmental and social impacts. A group of tour operators from different parts of the world have joined forces to create the Tour Operators' Initiative for Sustainable Tourism Development. With this initiatives, tour operators are moving towards sustainable tourism by committing themselves to address the environmental, social, and cultural aspects of sustainable development within the tourism sector. [Italian] Lo scopo del presente lavoro e' individuare il ruolo dei Tour Operator nel perseguire uno sviluppo sostenibile ossia un processo di sviluppo che lasci alle generazioni future lo stesso capitale, naturale e creato dall'uomo, di cui dispone l'attuale generazione. Il turismo e' tra le industrie globali piu' vaste ed in rapida crescita che crea una occupazione ed uno sviluppo economico significativo, particolarmente in molti paesi in via di sviluppo. Il turismo puo' anche generare impatti sia ambientali che sociali derivanti dallo sfruttamento delle risorse, dall'inquinamento, dalla produzione di rifiuti e dalla compromissione delle culture locali introducendo

  10. Tour operators, environment and sustainable development; Tour operator, ambiente e sviluppo sostenibile

    Energy Technology Data Exchange (ETDEWEB)

    Andriola, L; Chirico, R; Declich, P [ENEA, Divisione Caratterizzazione dell' Ambiente e del Territorio, Centro Ricerche Casaccia, Rome (Italy)

    2001-07-01

    The purpose of this work is to characterize the role of the tour operators in achieving sustainable development meaning a process of development which leaves at least the same amount of capital, natural and man-made, to future generations as current generations have access to. Tourism is one of the largest and fastest growing global industries, creating significant employment and economic development, particularly in many developing countries. Tourism can also have negative environmental and social impact resulting from resource consumption, pollution, generation of wastes and from the compromise of local culture while introducing new activities. Most tour operators has started to recognised that a clean environment is critical to their success, but few tour operators have the management tools or experience to design and conduct tours that minimize their negative environmental and social impacts. A group of tour operators from different parts of the world have joined forces to create the Tour Operators' Initiative for Sustainable Tourism Development. With this initiatives, tour operators are moving towards sustainable tourism by committing themselves to address the environmental, social, and cultural aspects of sustainable development within the tourism sector. [Italian] Lo scopo del presente lavoro e' individuare il ruolo dei Tour Operator nel perseguire uno sviluppo sostenibile ossia un processo di sviluppo che lasci alle generazioni future lo stesso capitale, naturale e creato dall'uomo, di cui dispone l'attuale generazione. Il turismo e' tra le industrie globali piu' vaste ed in rapida crescita che crea una occupazione ed uno sviluppo economico significativo, particolarmente in molti paesi in via di sviluppo. Il turismo puo' anche generare impatti sia ambientali che sociali derivanti dallo sfruttamento delle risorse, dall'inquinamento, dalla produzione di rifiuti e dalla compromissione delle culture locali introducendo nuove attivita'. La maggiore parte dei

  11. Targeting Neutrophil Protease-Mediated Degradation of Tsp-1 to Induce Metastatic Dormancy

    Science.gov (United States)

    2017-10-01

    AWARD NUMBER: W81XWH-16-1-0615 TITLE: Targeting Neutrophil Protease-Mediated Degradation of Tsp-1 to Induce Metastatic Dormancy PRINCIPAL...29 Sep 2017 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER Targeting Neutrophil Protease-Mediated Degradation of Tsp-1 to Induce Metastatic Dormancy...infection or cigarette smoke enhanced pulmonary metastasis from breast cancer in humans and mice. Similarly, autoimmune arthritis, characterized by

  12. Comparing the effectiveness of virtual and traditional forestry field tours

    OpenAIRE

    Easley, Elissa C.; Fletcher, Richard A.; Jensen, Edward C.; Rickenbach, Mark

    2002-01-01

    Virtual tours are among the many new Internet-based tools with potential applications in natural resource education. While technology exists to create virtual tour Web sites, little is understood about how they meet educational objectives and whether they can be complementary alternatives for traditional field tours. The Sustainable Forestry Partnership and the Forestry Media Center at Oregon State University created parallel virtual and field tours to compare these teaching techniques. Both ...

  13. Touring the Campus Library from the World Wide Web.

    Science.gov (United States)

    Mosley, Pixey Anne; Xiao, Daniel

    1996-01-01

    The philosophy, design, implementation and evaluation of a World Wide Web-accessible Virtual Library Tour of Texas A & M University's Evans Library is presented. Its design combined technical computer issues and library instruction expertise. The tour can be used to simulate a typical walking tour through the library or heading directly to a…

  14. The Mice Drawer System Tissue Sharing Program (MDS-TSP)

    Science.gov (United States)

    Biticchi, Roberta; Cancedda, Ranieri; Cilli, Michele; Cotronei, Vittorio; Costa, Delfina; Liu, Yi; Piccardi, Federica; Pignataro, Salvatore; Ruggiu, Alessandra; Tasso, Roberta; Tavella, Sara

    obtain from the animals sent to the ISS as much as possible information including also microgravity induced modifications of tissues other than bone, we associated to the MDS experiment several international group from Italian, American, Japanese Universities and from NASA and JAXA labs and we created a Tissue Sharing Program (TSP). In total 17 groups from 6 countries were involved in the program. The MDS payload containing three PTN-transgenic mice (Tg) and three wild type (Wt) mice was launched with the Shuttle STS-128, on August, 28 2009 and the MDS transferred to the ISS for three months. The payload re-entry was with the Shuttle STS-129 on November, 27 2009 in Florida. Unfortunately during this period 3 mice (two Wt and one Tg) died due to a spinal cord lesion probably occurred during the shuttle lift off, a liver pathology and a failure of the food delivery system respectively. All the three dead mice were however frozen for subsequent skeletal analysis. The remaining 3 mice had a normal behavior during the flight and appeared in excellent health conditions at the time of landing. During the MDS stay at the ISS several physical parameters were under daily check. With regard to the animal health status checking, the daily water consumption for each individual mouse revealed to be one of the most important parameter. Immediately after landing the mice were sacrificed, blood parameter were measured and all different tissues were dissected. Samples from almost the entire organism are now under investigation by the TSP team. A ground replica of the flight experiment ("ground control") was performed at the University of Genova from November 2009 to the second week of February 2010. Some of the initial results from the flight and the ground control experiments are presented in the individual abstracts.

  15. Evaluation of the Kids' Shop Smart tour.

    Science.gov (United States)

    Smith, Shannon C; Kalina, Laura

    2004-01-01

    We investigated the impact of the Kids' Shop Smart Tour program on participants' attitudes toward trying new foods and eating a variety of foods, as well as their recognition of Canada's Food Guide to Healthy Eating. Data were collected from parents/caregivers, students in kindergarten to grade 3, and teachers; questionnaires, quizzes, and interviews were used. Questionnaires were sent home with 947 students; 52% of parents/caregivers returned completed questionnaires. Many parents/caregivers reported that their children tried and liked unfamiliar foods on the tour. No significant difference was detected in children's willingness to try new foods or consumption of a greater variety of food before and after the tour. Quiz score differences between participants and a comparison group were not statistically significant. Of the 38 teachers who completed interviews, 97% reported that the program helped them meet curriculum requirements; 95% would recommend the resource to other teachers. Quantitative findings do not indicate that the program increases children's willingness to try new foods or eat a greater variety of food. However, qualitative data revealed that some parents observed their children trying new foods more willingly and demonstrating greater knowledge of and interest in Canada's Food Guide to Healthy Eating. Further research with validated measurement tools is recommended to establish the effectiveness of the Kids' Shop Smart Tour.

  16. Kathryn Toure | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    Kathryn Toure started her career in New York City in refugee resettlement before working for the Centre for International and Comparative Studies at the University of Iowa. She moved to West Africa where she worked with Africa Online, the Educational Research Network for West and Central Africa, and eventually as ...

  17. The Virtual Grand Tour as Educational Paradigm

    DEFF Research Database (Denmark)

    Hansen, Per Skafte; Mouritsen, Lars

    2001-01-01

    The Virtual Grand Tour as defined here bears some resemblance to its 18th century ancestor: a wide range of individual topics are treated as a whole; a tutor, whether real or simulated, present or remote, is provided; a set of problem solving tools forms an integrated part of the "traveller...

  18. Virtual Tour by AMFI - VR app

    NARCIS (Netherlands)

    van Vliet, Harry; Riester, Jochen

    2014-01-01

    By using Google Cardboard we have developed world’s first virtual tour on your smartphone of a fashion retail space: the byAMFI Statement Store, located in the city centre of Amsterdam. byAMFI is the Statement Store of the Amsterdam Fashion Institute that is a part of the Amsterdam University of

  19. Reisipakkumine - Grand Tour Itaalias / Mai Levin

    Index Scriptorium Estoniae

    Levin, Mai, 1942-

    2009-01-01

    Tiina Abeli koostatud ja Urmas Viigi kujundatud näitus "Grand Tour. Eesti kunstnikud Itaalias" Kumu Kunstimuuseumis 05. aprillini. Loetletud eksponeeritud tööde autoreid. Näitus annab ülevaate, kes siinsetest kunstnikest 19. sajandi algusest kuni 1930ndate aastateni Itaalias käisid ja kuidas see nende loomingut mõjutas

  20. Park World Tour Hiinas / Timo Sild

    Index Scriptorium Estoniae

    Sild, Timo, 1988-

    2012-01-01

    Reisikiri Eesti sportlaste osalemisest septembris Hiinas korraldatud Park World Tour orienteerumisvõistlustel - Changchunis toimunud kahepäevasel Vasa orienteerumisfestivalil, Chongqingi lähistel toimunud Hiina meistrivõistlustel orienteerumissprindis ja Wanshengis toimunud lühiraja Hiina meistrivõistlustel ning Bekingi botaanikaaias toimunud keskkooli ja ülikooli meistrivõistlustel

  1. The Cassette Tour: An Effective, Efficient Orientation.

    Science.gov (United States)

    Poirier, Gayle

    1992-01-01

    Describes the development, use, promotion, and student evaluation of a 25-minute audiocassette tour of the Louisiana State University library, which was developed as a pilot project by the bibliographic instruction librarian in 1990. Notes that student suggestions have been instrumental in the development of more tool and subject specific…

  2. COOBBO: A Novel Opposition-Based Soft Computing Algorithm for TSP Problems

    Directory of Open Access Journals (Sweden)

    Qingzheng Xu

    2014-12-01

    Full Text Available In this paper, we propose a novel definition of opposite path. Its core feature is that the sequence of candidate paths and the distances between adjacent nodes in the tour are considered simultaneously. In a sense, the candidate path and its corresponding opposite path have the same (or similar at least distance to the optimal path in the current population. Based on an accepted framework for employing opposition-based learning, Oppositional Biogeography-Based Optimization using the Current Optimum, called COOBBO algorithm, is introduced to solve traveling salesman problems. We demonstrate its performance on eight benchmark problems and compare it with other optimization algorithms. Simulation results illustrate that the excellent performance of our proposed algorithm is attributed to the distinct definition of opposite path. In addition, its great strength lies in exploitation for enhancing the solution accuracy, not exploration for improving the population diversity. Finally, by comparing different version of COOBBO, another conclusion is that each successful opposition-based soft computing algorithm needs to adjust and remain a good balance between backward adjacent node and forward adjacent node.

  3. Culture phenomenon analysis on the forest tour activity of China

    Institute of Scientific and Technical Information of China (English)

    Jiang Minjin

    2006-01-01

    This paper analyzes culture and forest culture, the intension of culture and forest culture, combines the understanding of the main cultural factor with the forest tour activity of China, analyzes the compatible phenomenon of Chinese forest culture and traditional culture, and explores culture of forest tourist site containing the meaning in forest tour. The author thinks the tour of forest culture which will be the important component of forest tour in forest culture,This paper puts forward simple questions existing in exploitation and advantage of forest tour culture, and proposes some countermeasures.

  4. Extraction and Characterization of Tamarind (Tamarind indica L. Seed Polysaccharides (TSP from Three Difference Sources

    Directory of Open Access Journals (Sweden)

    Khanittha Chawananorasest

    2016-06-01

    Full Text Available Tamarind seed polysaccharide (TSP, a natural polysaccharide extracted from tamarind seeds is used in the pharmaceutical, textile and food industries as a mucoadhesive polymer. This work aimed to extract TSP from tamarind seeds from three sources with two methods and characterized its physical and chemical properties. Kernel powder of tamarind seeds was slurried into a clear solution, set aside overnight and then centrifuged at 6000 rpm for 20 min to separate all foreign matter. The supernatant was separated and poured into excess 95% ethanol with continuous stirring. The precipitate obtained was collected and dried in the oven and then the dried TSP polymer was stored in a desiccator. The dried TSP was analyzed by 1H-NMR, FT-IR and XRD. The results showed TSP from tamarind seeds taken from paddy farmland (A, a waste from the export tamarind juice industry (B and the export tamarind powder industry(C gave yields of 31.55%, 26.95% and 17.30%, respectively, using method 1 and 11.15%, 53.65% and 54.65%, with method 2, respectively, but method 2 gave purer TSP than method 1. The FT-IR spectra displayed peaks at 3351.95 cm−1, 2920.76 cm−1, 1018.85 cm−1 and 555.16 cm−1. The 1H-NMR showed polysaccharide peaks between δ 3.50–4.20 ppm and XRD diagrams indicated their amorphous nature. Future works will focus on the quantitative analysis, biological activity and possible use of TSP as a drug delivery system.

  5. Exploiting Elementary Landscapes for TSP, Vehicle Routing and Scheduling

    Science.gov (United States)

    2015-09-03

    similar mathematical foundation to enable gradient descent methods for discrete combinatorial optimization problems. We are also generalizing our prior...research has exploited statistical and mathematical properties of elementary landscapes to develop new gradient methods for combinatorial optimization... mathematically methods to more automatically identify elementary landscapes. If a combinatorial optimization problem is a superposition of elemen

  6. Incorporation Between AHP and N-TSP for Plant Surveillance Routing with Multiple Constraints

    International Nuclear Information System (INIS)

    Djoko Hari Nugroho

    2002-01-01

    This paper observed plant on-line surveillance routing for maintenance management with multiple constraints using TSP (Traveling Salesman Problem). In the research N-TSP (nomadic TSP) type was used. In this case, on-line surveillance could be implemented on moving robot. Route for preventive maintenance management was observed sequentially per stage using multiple constraints (a) distance between components, and (b) failure probability of components using AHP (Analytical Hierarchy Process). Simulation was observed utilizing DURESS as a complex system. The simulation result showed that the route with single constraint distance between components represents the sequence of 1 - 6 - 2 - 4 - 3 - 5. Routing for DURESS with multiple constraints using incorporation of AHP and TSP showed that the first priority in the route is flow sensor FB2 with the value of comparation of 0.1042. The next priority is sequentially FB1, FA2, FA1, FA, FB, VB, VA, VA1, VA2, VB1, VB2, pump B, pump A, FR1, FR2, reservoir 2, and reservoir 1. Numerical experiment obtained that the incorporation between AHP and N-TSP has successfully constructed the surveillance routing with multiple constraints. (author)

  7. STRATEGI PEMASARAN PAKET WISATA PADA PT. PANDAWA LIMA TOUR AND TRAVEL INDONESIA DI DENPASAR

    OpenAIRE

    I Gede Adhi Suputra Arimbawa PG.; I GPB. Sasrawan Mananda; I Putu Sudana

    2017-01-01

    This research is about the marketing strategies implemented by PT. Pandawa Lima Tour and Travel tour packages. Company offers tour packages in Bali and beyond Bali tour packages with variety of facilities. As a common general company, PT. Pandawa Lima Tour and Travel has the objective to make profit and trying to satisfy consumers. This research aims to determine the marketing strategy package in PT. Pandawa Lima Tour and Travel tour package in Denpasar. The data collection method in research...

  8. A unified grand tour of theoretical physics

    CERN Document Server

    Lawrie, Ian D

    2013-01-01

    A Unified Grand Tour of Theoretical Physics invites its readers to a guided exploration of the theoretical ideas that shape our contemporary understanding of the physical world at the fundamental level. Its central themes, comprising space-time geometry and the general relativistic account of gravity, quantum field theory and the gauge theories of fundamental forces, and statistical mechanics and the theory of phase transitions, are developed in explicit mathematical detail, with an emphasis on conceptual understanding. Straightforward treatments of the standard models of particle physics and cosmology are supplemented with introductory accounts of more speculative theories, including supersymmetry and string theory. This third edition of the Tour includes a new chapter on quantum gravity, focusing on the approach known as Loop Quantum Gravity, while new sections provide extended discussions of topics that have become prominent in recent years, such as the Higgs boson, massive neutrinos, cosmological perturba...

  9. Virtual Tour by AMFI - VR app

    OpenAIRE

    van Vliet, Harry; Riester, Jochen

    2014-01-01

    By using Google Cardboard we have developed world’s first virtual tour on your smartphone of a fashion retail space: the byAMFI Statement Store, located in the city centre of Amsterdam. byAMFI is the Statement Store of the Amsterdam Fashion Institute that is a part of the Amsterdam University of Applied Sciences. It offers a platform to showcase the beautiful work that is made by our students, teachers and alumni.

  10. STRATEGI PEMASARAN PAKET INBOUND TOUR: STUDI KASUS DI PT. LOTUS ASIA TOURS JIMBARAN BALI

    Directory of Open Access Journals (Sweden)

    Camelia Agatha Mahayu Putri

    2015-12-01

    Full Text Available Tujuan penelitian ini adalah untuk mengetahui faktor internal yaitu kekuatan dan kelemahan dan eksternal yaitu peluang dan ancaman dari PT. Lotus Asia Tours serta untuk mengetahui strategi yang dapat dilakukan pihak PT. Lotus Asia Tours untuk memasarkan paket inbound tour. Lokasi penelitian dilakukan di PT. Lotus Asia Tours yang terletak di Jl. By Pass Ngurah Rai No. 18, Jimbaran Bali.. Penelitian ini menggunakan metode deskriptif kualitatif. Teknik pengumpulan data dilakukan dengan cara observasi, wawancara, studi kepustakaan, studi dokumentasi dan didukung dengan daftar pertanyaan yang disebarkan kepada 60 informan. Daftar pertanyaan yang disebarkan berpedoman pada indikator marketing mix 7 P (product, price, place, promotion, physical evidence, people, process. Hasil data yang diperoleh lalu dianalisis dengan IFAS (Internal Factor Analysis Summary dan EFAS ( External Factor Analysis Summary, selanjutnya untuk mengetahui posisi perusahaan digunakan matriks internal eksternal dan untuk mengetahui alternatif strategi digunakan matriks SWOT, sehingga dapat menciptakan strategi pemasaran baru serta mengembangkan program-program yang telah ada agar dapat diterapkan oleh PT. Lotus Asia Tours Jimbaran Bali. Berdasarkan hasil penelitian diperoleh total nilai rata-rata lingkungan internal yaitu sebesar 3,01 dan lingkungan eksternal yaitu sebesar 2,96, dapat diketahui bahwa posisi perusahaan berada di sel IV yang berarti stability strategy dimana strategi yang tetapkan tidak merubah arah strategi yang telah ada.

  11. BECOMING A TOUR GUIDE: ANALYZING THE MOTIVATIONS

    Directory of Open Access Journals (Sweden)

    Monika PRAKASH

    2010-06-01

    Full Text Available Guides play a vital role in this process bringing satisfaction to tourists visiting a country or region/state. The opportunity of direct interaction with the tourists makes them all the more responsible for projecting the correct image of the country/region, giving factually correct information about the destination, ensuring the safety and well being of the tourists as well as pleasing and satisfying the stay for them during their visits. Over last few years there has been a greater interest in tour guide profession especially in the northern region of India.The purpose of this study is to identify the motivations that led to choosing tour guiding as a profession and career. There appears to be a significant difference in such motivation in different regions of the country. A comparison in motivations in two regions (north vs. east was made. Based on primary data collection paper attempts to discuss what has motivated the youth to take up tour guiding profession- whether such motivation is positive of negative. In either case policy makers may decide what type of support programs need to be introduced by the state and other agencies like educational, rearing and counselling, financial support, social security, or any other type of interventions.

  12. DNA Vaccine Encoding the Chimeric Form of Schistosoma mansoni Sm-TSP2 and Sm29 Confers Partial Protection against Challenge Infection

    Science.gov (United States)

    Gonçalves de Assis, Natan Raimundo; Batistoni de Morais, Suellen; Figueiredo, Bárbara Castro Pimentel; Ricci, Natasha Delaqua; de Almeida, Leonardo Augusto; da Silva Pinheiro, Carina; Martins, Vicente de Paulo; Oliveira, Sergio Costa

    2015-01-01

    Schistosomiasis is an important parasitic disease worldwide that affects more than 207 million people in 76 countries and causes approximately 250,000 deaths per year. The best long-term strategy to control schistosomiasis is through immunization combined with drug treatment. Due to the ability of DNA vaccines to generate humoral and cellular immune responses, such vaccines are considered a promising approach against schistosomiasis. Sm29 and tetraspanin-2 (Sm-TSP2) are two proteins that are located in the S. mansoni tegument of adult worms and schistosomula and induce high levels of protection through recombinant protein immunization. In this study, we transfected BHK-21 cells with plasmids encoding Sm29, Sm-TSP2 or a chimera containing both genes. Using RT-PCR analysis and western blot, we confirmed that the DNA vaccine constructs were transcribed and translated, respectively, in BHK-21 cells. After immunization of mice, we evaluated the reduction in worm burden. We observed worm burden reductions of 17-22%, 22%, 31-32% and 24-32% in animals immunized with the pUMVC3/Sm29, pUMVC3/SmTSP-2, pUMVC3/Chimera and pUMVC3/Sm29 + pUMVC3/SmTSP-2 plasmids, respectively. We evaluated the humoral response elicited by DNA vaccines, and animals immunized with pUMVC3/Sm29 and pUMVC3/Sm29 + pUMVC3/SmTSP-2 showed higher titers of anti-Sm29 antibodies. The cytokine profile produced by the spleen cells of immunized mice was then evaluated. We observed higher production of Th1 cytokines, such as TNF-α and IFN-γ, in vaccinated mice and no significant production of IL-4 and IL-5. The DNA vaccines tested in this study showed the ability to generate a protective immune response against schistosomiasis, probably through the production of Th1 cytokines. However, future strategies aiming to optimize the protective response induced by a chimeric DNA construct need to be developed. PMID:25942636

  13. DNA Vaccine Encoding the Chimeric Form of Schistosoma mansoni Sm-TSP2 and Sm29 Confers Partial Protection against Challenge Infection.

    Directory of Open Access Journals (Sweden)

    Natan Raimundo Gonçalves de Assis

    Full Text Available Schistosomiasis is an important parasitic disease worldwide that affects more than 207 million people in 76 countries and causes approximately 250,000 deaths per year. The best long-term strategy to control schistosomiasis is through immunization combined with drug treatment. Due to the ability of DNA vaccines to generate humoral and cellular immune responses, such vaccines are considered a promising approach against schistosomiasis. Sm29 and tetraspanin-2 (Sm-TSP2 are two proteins that are located in the S. mansoni tegument of adult worms and schistosomula and induce high levels of protection through recombinant protein immunization. In this study, we transfected BHK-21 cells with plasmids encoding Sm29, Sm-TSP2 or a chimera containing both genes. Using RT-PCR analysis and western blot, we confirmed that the DNA vaccine constructs were transcribed and translated, respectively, in BHK-21 cells. After immunization of mice, we evaluated the reduction in worm burden. We observed worm burden reductions of 17-22%, 22%, 31-32% and 24-32% in animals immunized with the pUMVC3/Sm29, pUMVC3/SmTSP-2, pUMVC3/Chimera and pUMVC3/Sm29 + pUMVC3/SmTSP-2 plasmids, respectively. We evaluated the humoral response elicited by DNA vaccines, and animals immunized with pUMVC3/Sm29 and pUMVC3/Sm29 + pUMVC3/SmTSP-2 showed higher titers of anti-Sm29 antibodies. The cytokine profile produced by the spleen cells of immunized mice was then evaluated. We observed higher production of Th1 cytokines, such as TNF-α and IFN-γ, in vaccinated mice and no significant production of IL-4 and IL-5. The DNA vaccines tested in this study showed the ability to generate a protective immune response against schistosomiasis, probably through the production of Th1 cytokines. However, future strategies aiming to optimize the protective response induced by a chimeric DNA construct need to be developed.

  14. Detrusor Arreflexia as an End Stage of Neurogenic Bladder in HAM/TSP?

    Directory of Open Access Journals (Sweden)

    Matheus Tannus

    2011-01-01

    Full Text Available The HTLV-1 virus is a known agent involved in the development of HAM/TSP. Past studies have typically observed patients with autonomic dysfunction consisting of detrusor overactivity and detrusor-sphincter dyssynergia, with the occasional observation of underactive detrusor or detrusor arreflexia. However, studies have not yet evaluated the progression of neurogenic bladder over time. In this paper, we describe a HAM/TSP patient with the initial development of overactive detrusor, and subsequent development of detrusor arreflexia. Given a paucity of studies characterizing the effects of HTLV-1 on the autonomic nervous system, particularly aspects controlling continence, this patient's clinical course may represent one type of end point for patients with HAM/TSP and neurogenic bladder. Further cohort or case-series studies, with particular emphasis on the progression of neurogenic bladder, are needed to evaluate the significance of this described case in relation to typical disease progression patterns.

  15. TU-E-TOUR-T-00: Exhibit Hall Guided Tours-Microdosimeters for Therapy (Tuesday)

    International Nuclear Information System (INIS)

    2016-01-01

    Tour Leader: Indra Das, NYU Langone Medical Center, New York, NY Tour Guides: Hsui Ai, Indiana University School of Medicine, Indianapolis, IN Aaron Andersen, Indiana University School of Medicine, Indianapolis, IN Olga Volotoskova, NYU Langone Medical Center, New York, NY Participating Vendors: IBA PTW – New York RTI Electronics, Inc. Standard Imaging, Inc. Sun Nuclear Corporation Small fields are increasing used in specialized radiation treatments such as Gammaknife, Cyberknife, Tomotherapy, IMRT, VMAT, SRS and SBRT. Due to small field size electron transport creates lateral electronic disequilibrium and thus dosimetry could be very difficult. Microdetectors are used for small field dosimetry which will be discussed in preface of this tour as below: Understanding small field e.g. meaning and definition of small field IAEA definition and approach Characteristics of microdetectors in terms of perturbation, recombination, correction Suitability of microdetectors in small field dosimetry

  16. Creating Three New Bike Tours in Santiago de Chile Case Study: Huaso Tours & Bike Rental

    OpenAIRE

    Heino, Jenni

    2015-01-01

    The purpose of this Bachelor´s thesis was to create new bike tour services for the thesis case company Huaso Tours & Bike Rental, based in Santiago de Chile. The idea for the thesis was perceived from a free time activity of mountain biking in Santiago de Chile´s popular tourist attraction San Cristobal hill. This park draws thousands of bikers monthly to enjoy the green areas of the city, however, there is no mountain bike service offered to visit this hill. By conducting a small pre-researc...

  17. Business Plan for Launching a Luxury Adventure Tour Operator Based in Canada

    OpenAIRE

    Hung, Greg; Khlystov, Nikolai

    2011-01-01

    MOT Elite Travel Experiences (METE) is a tour operator and online travel agent start-up company based in Vancouver, British Columbia. METE is faced with the challenge of establishing itself as a business in the travel industry. However, recent advances in technology such as an increase in the number of broadband Internet users, search engine optimization, and the advent of smartphones have created an opportunity to capitalize on the growing popularity of online travel booking services. This t...

  18. 5 CFR 1605.22 - Claims for correction of Board or TSP record keeper errors; time limitations.

    Science.gov (United States)

    2010-01-01

    ... record keeper errors; time limitations. 1605.22 Section 1605.22 Administrative Personnel FEDERAL... § 1605.22 Claims for correction of Board or TSP record keeper errors; time limitations. (a) Filing claims... after that time, the Board or TSP record keeper may use its sound discretion in deciding whether to...

  19. 41 CFR 102-118.195 - What documents must a transportation service provider (TSP) send to receive payment for a...

    Science.gov (United States)

    2010-07-01

    ... transportation service provider (TSP) send to receive payment for a transportation billing? 102-118.195 Section... must a transportation service provider (TSP) send to receive payment for a transportation billing? For... Government Billing Documents Terms and Conditions Governing Acceptance and Use of A Government Bill of Lading...

  20. 41 CFR 102-118.260 - Must my agency send all quotations, tenders, or contracts with a TSP to GSA?

    Science.gov (United States)

    2010-07-01

    ... quotations, tenders, or contracts with a TSP to GSA? 102-118.260 Section 102-118.260 Public Contracts and... REGULATION TRANSPORTATION 118-TRANSPORTATION PAYMENT AND AUDIT Use of Government Billing Documents Quotations, Tenders Or Contracts § 102-118.260 Must my agency send all quotations, tenders, or contracts with a TSP to...

  1. Wisata Bencana : Sebuah Studi Kasus Lava Tour Gunung Merapi

    Directory of Open Access Journals (Sweden)

    Zein Mufarrih Muktaf

    2017-09-01

    ABSTRACK The emergence of ecotourism trends as part of nature tourism to be an offer for tourists who want to feel the sensation of different tourist. In addition to the emergence of ecotourism, also appeared many other sort of tourism, such as dark tourism and disaster tourism. Dark tourism and disaster tourism is interesting enough to be discussion. The quention of this research is how the phenomenon of disaster tourism on Lava Tour in Mount Merapi? The purpose of this research is to know the practice of disaster tour “Lava Tour” Mount Merapi. The object of research is community-based tourism in Lava Tour area located in Disaster Prone Area (Kawasan Rawan Bencana III. Research method using case study approach. The conclusion of this research is, first, disaster tour is educational tour which destruction, death and back a life as tourist attraction. Secondly, that disaster tour presents a trip or tour because tourists can direct to see the disaster site. Third, the role of communication between the community-based tourism to the tourists are very important, such as telling the chronology of events to the tourists. It is better if the source of information teller is a direct victim or a direct eye witness, because it is more authentic and convincing. Fourth, disaster tourism prefers the interaction between witnesses and tourists. Fifth, disaster tours can be part of disaster literacy, as witnesses or victims explain a lot about disaster. Keywod : disaster tourism; tour; Mount Merapi; Tourism Communication; disaster literacy

  2. TOUR CONSTRUCTION HEURISTICS FOR AN ORDER SEQUENCING PROBLEM

    Directory of Open Access Journals (Sweden)

    De Villiers, A. P.

    2012-11-01

    Full Text Available An order picking system that requires pickers to move in a clockwise direction around a picking line with fixed locations is considered. The problem is divided into three tiers. The tier in which orders must be sequenced is addressed. Eight tour construction heuristics are developed and implemented for an order picking system operating in unidirectional picking lines. Two classes of tour construction heuristics the tour construction starting position ( and the tour construction ending position ( are developed to sequence orders in a picking line. All algorithms are tested and compared using real life data sets. The best solution quality was obtained by a heuristic with adaptations.

  3. The Response to P-Derived from Phosphate Rock and TSP by Crops Grown in a Simulated Crop Rotation System

    International Nuclear Information System (INIS)

    Sisworo, Elsye L; Sisworo, Widjang H; Havid-Rasjid; Syamsul-Rizal; Komarudin-Idris

    2002-01-01

    A green house experiment was carried out on a simulated crop rotation system of upland rice-soybean-mungbean to determine the effect of P-derived from different phosphate rock (PR) sources and TSP using 32 P. The data obtained reveal that all the P-sources has a significant effect on the growth of all the three crops, expressed in dry weight, % P-total and total P-uptake (mg P pot -1 ). For the P-source it was shown that % P-derived from PR/TSP and their uptake (mg P pot -1 ) was quite high, showing that the PR s applied were of good reactivity. The residue of the PR s has also still a good effect on plant growth than that of TSP. The efficiency of PR s was far below that of TSP. This apparently was due to the high rate of application, ten times the rate of TSP. (author)

  4. Optimization of travel salesman problem using the ant colony system and Greedy search

    International Nuclear Information System (INIS)

    Esquivel E, J.; Ordonez A, A.; Ortiz S, J. J.

    2008-01-01

    In this paper we present some results obtained during the development of optimization systems that can be used to design refueling and patterns of control rods in a BWR. These systems use ant colonies and Greedy search. The first phase of this project is to be familiar with these optimization techniques applied to the problem of travel salesman problem (TSP). The utility of TSP study is that, like the refueling design and pattern design of control rods are problems of combinative optimization. Even, the similarity with the problem of the refueling design is remarkable. It is presented some results for the TSP with the 32 state capitals of Mexico country. (Author)

  5. Approximation algorithms for deadline-TSP and vehicle routing with time-windows

    NARCIS (Netherlands)

    Bansal, N.; Blum, A.; Chawla, S.; Meyerson, A.; Babai, L.

    2004-01-01

    Given a metric space G on n nodes, with a start node r and deadlines D(v) for each vertex v, we consider the Deadline-TSP problem of finding a path starting at r that visits as many nodes as possible by their deadlines. We also consider the more general Vehicle Routing with Time-Windows problem, in

  6. 5 CFR 839.1119 - How is the actuarial reduction for TSP computed?

    Science.gov (United States)

    2010-01-01

    ... benefit that is payable, the present value factor for the survivor's age at the time of death is used. The survivor benefit is not reduced for TSP if the retiree's rate was reduced. Survivor Benefits ... reduction. OPM will divide the Government contributions and earnings by the present value factor for your...

  7. Team Software Process (TSP) Coach Mentoring Program Guidebook Version 1.1

    Science.gov (United States)

    2010-06-01

    Hodgins, Michelle Jurkouich, Delwyn Kellogg, Juan Lopez, Andy Oughton, Rafael Salazar, and Jim Van Buren. vi | CMU/SEI-2010-SR-016 vii | CMU/SEI...which it was deemed that TSP coaches must be competent; Sections C through G (listed below in bold font ) are areas that should be of particular

  8. Characteristic of total suspended particulate (TSP) containing Pb and Zn at solid waste landfill

    Science.gov (United States)

    Budihardjo, M. A.; Noveandra, K.; Samadikun, B. P.

    2018-05-01

    Activities conducted at municipal solid waste landfills (MSWLs) potentially cause air pollution. Heavy vehicles in MSWLs release various pollutants that can have negative impacts for humans. One noticeable pollutant at MSWLs is airborne total suspended particulate (TSP) which may contain heavy metals such as Pb and Zn and can cause disease when inhaled by humans. In this study, TSP from a landfill in Semarang, Indonesia was collected and characterized to quantify the concentration of Pb and Zn. Meteorological factors (i.e. temperature, humidity and wind velocity) and landfill activities were considered as factors affecting pollutant concentrations. TSP was sampled using dust samplers while the concentrations of heavy metals in TSP were analyzed using an Atomic Absorption Spectrophotometer (AAS). Pb concentration ranged from 0.84 to 1.78 µg/m3 while Zn concentration was from 7.87 to 8.76 µg/m3. The levels of Pb were below the threshold specified by the Indonesian Government. Meanwhile, the threshold for Zn has not yet been determined.

  9. Sociorobot world a guided tour for all

    CERN Document Server

    Tzafestas, Spyros

    2016-01-01

    This book makes a consolidated guided tour to the world of sociorobots (social or socialized robots). Sociorobots and assistive robots provide entertainment, assistance to the handicapped, companionship to the elderly, and health care to autistic children and people with dementia among others. The book provides, in a fluent educational way, all major concepts, architectures, and design methodologies. All types of sociorobots are examined, namely walking anthropomorphic, wheeled anthropomorphic, fixed-place anthropomorphic, and zoomorphic sociorobots. The book provides an outline of sociorobot intelligent control architectures, robot learning, and human robot interaction.

  10. Grand Tour: immaginario, territorio e culture digitali

    Directory of Open Access Journals (Sweden)

    Emiliano Ilardi

    2016-12-01

    Full Text Available Il Grand Tour può essere recuperato come asset narrativo utile per un intervento strategico di re-branding del viaggio in Italia? Il contributo analizza il contesto e le condizioni per una progettazione di questo livello nell’ambiente culturale dell’epoca digitale. Considerando gli archetipi moderni della mediazione dei luoghi come una grande riserva di senso, da riattivare sia nelle pratiche basate sui format seriali e transmediali che valorizzano i territori nella produzione creativa, sia nella costruzione di infrastrutture digitali e  transluoghi per la valorizzazione degli attrattori culturali.

  11. ITER Council tour of Clarington site

    International Nuclear Information System (INIS)

    Dautovich, D.

    2001-01-01

    The ITER Council meeting was recently held in Toronto on 27 and 28 February. ITER Canada provided local arrangements for the Council meeting on behalf of Europe as the Official host. Following the meeting, on 1 March, ITER Canada conducted a tour of the proposed ITER construction site at Charington, and the ITER Council members attended a luncheon followed by a speech by Dr. Peter Barnard, Chairman and CEO of ITER Canada, at the Empire Club of Canada. The official invitation to participate in these events came from Dr. Peter Harrison, Deputy Minister of Natural Resources Canada. This report provides a brief summary of the events on 1 March

  12. Improved exact method for the double TSP with multiple stacks

    DEFF Research Database (Denmark)

    Lusby, Richard Martin; Larsen, Jesper

    2011-01-01

    and delivery problems. The results suggest an impressive improvement, and we report, for the first time, optimal solutions to several unsolved instances from the literature containing 18 customers. Instances with 28 customers are also shown to be solvable within a few percent of optimality. © 2011 Wiley...... the first delivery, and the container cannot be repacked once packed. In this paper we improve the previously proposed exact method of Lusby et al. (Int Trans Oper Res 17 (2010), 637–652) through an additional preprocessing technique that uses the longest common subsequence between the respective pickup...

  13. Secondary side TSP deposit buildup: lab test investigation focused on electrokinetic considerations

    Energy Technology Data Exchange (ETDEWEB)

    Barale, M.; Guillodo, M.; Foucault, M., E-mail: Morgan.Barale@areva.com [AREVA NP SAS, Technical Centre, Le Creusot (France); Ryckelynck, N.; Clinard, M-H.; Chahma, F.; Brun, C. [AREVA NP SAS, Chemistry and Radiochemistry Group, Paris (France); Corredera, G. [Electricite de France, Centre d' Expertise et d' Inspection dans les domaines de la Realisation et de l' Exploitation, Saint-Denis (France)

    2010-07-01

    Deposit buildup which caused the clogging of the 'foils' of the upper tube-support-plates (TSP) inside a PWR steam generator of French NPPs in 2006 presents certain similarities with deposits observed in lab tests performed in secondary coolant chemistry at the Technical Centre of AREVA NP in 2002. The mechanism of TSP clogging seems not to present obvious phenomenological links with the fouling of the free span of SG since deposits buildup is quite uniform and is currently related to a surface boiling effect due to the surface heat flux. A specific mechanism could account for TSP clogging. In particular, electrokinetic effects were investigated by EDF-CEIDRE and AREVA NP SAS in the framework of a lab test program started in 2007. The electrokinetic approach is to consider that the coupling of local hydrodynamic and surface electrochemistry could lead to the formation of a very localized and heterogeneous deposit at the leading edge between both TSP and SG tubing material. Electrokinetic effects can lead to the oxidation and/or the precipitation of ferrous ions and to a variation of the electrokinetic potential which can produce strong attraction of iron oxide colloids. These electrokinetic effects are dependent of the T/H and local hydrodynamic conditions and surface electrochemistry explaining. The objective of this EDF-AREVA lab test program is to investigate the role of secondary chemistry coolant (pH, DH, N{sub 2}H{sub 4}, amine, redox) and of the nature of materials (SS, Ni base alloy) on deposit buildup. Properties of oxide surface and zeta potential of oxidized metallic materials have been also determined at temperature to understand their potential contribution on mechanism of TSP clogging in secondary side chemistry coolant. In this paper, a set of specific experiments carried out in this frame have been presented and discussed, paying particular attention to the effects of electrokinetic considerations and surface charges at oxide

  14. Secondary side TSP deposit buildup: lab test investigation focused on electrokinetic considerations

    International Nuclear Information System (INIS)

    Barale, M.; Guillodo, M.; Foucault, M.; Ryckelynck, N.; Clinard, M-H.; Chahma, F.; Brun, C.; Corredera, G.

    2010-01-01

    Deposit buildup which caused the clogging of the 'foils' of the upper tube-support-plates (TSP) inside a PWR steam generator of French NPPs in 2006 presents certain similarities with deposits observed in lab tests performed in secondary coolant chemistry at the Technical Centre of AREVA NP in 2002. The mechanism of TSP clogging seems not to present obvious phenomenological links with the fouling of the free span of SG since deposits buildup is quite uniform and is currently related to a surface boiling effect due to the surface heat flux. A specific mechanism could account for TSP clogging. In particular, electrokinetic effects were investigated by EDF-CEIDRE and AREVA NP SAS in the framework of a lab test program started in 2007. The electrokinetic approach is to consider that the coupling of local hydrodynamic and surface electrochemistry could lead to the formation of a very localized and heterogeneous deposit at the leading edge between both TSP and SG tubing material. Electrokinetic effects can lead to the oxidation and/or the precipitation of ferrous ions and to a variation of the electrokinetic potential which can produce strong attraction of iron oxide colloids. These electrokinetic effects are dependent of the T/H and local hydrodynamic conditions and surface electrochemistry explaining. The objective of this EDF-AREVA lab test program is to investigate the role of secondary chemistry coolant (pH, DH, N 2 H 4 , amine, redox) and of the nature of materials (SS, Ni base alloy) on deposit buildup. Properties of oxide surface and zeta potential of oxidized metallic materials have been also determined at temperature to understand their potential contribution on mechanism of TSP clogging in secondary side chemistry coolant. In this paper, a set of specific experiments carried out in this frame have been presented and discussed, paying particular attention to the effects of electrokinetic considerations and surface charges at oxide-solution interfaces

  15. The motor evoked potential in AIDS and HAM/TSP: state of the evidence.

    Science.gov (United States)

    Leon-Sarmiento, Fidias E; Elfakhani, Mohamed; Boutros, Nash N

    2009-12-01

    We aimed to better understand the involvement of the corticospinal tract, assessed by non-invasive transcranial stimulation, in order to determine the actual involvement of the motor system in patients with HAM/TSP and AIDS. An exhaustive MEDLINE search for the period of 1985 to 2008 for all articles cross-referenced for 'HTLV-I, HTLV-II, HTLV-III and HIV, HIV1, HIV2, evoked potential, motor evoked potential, high voltage electrical stimulation, transcranial magnetic stimulation, magnetic stimulation, corticomotor physiology, motor pathways, acquired immunodeficiency syndrome, AIDS, SIDA, tropical spastic paraparesis, HTLV-I-associated myelopathy, HAM, TSP, and HAM/TSP' were selected and analysed. Eighteen papers published in English, Spanish, Portuguese, French and Japanese were identified. Only the central motor conduction time has been analyzed in seropositive patients to human retroviruses. The investigations done on HAM/TSP support the involvement of the pyramidal tract mainly at lower levels, following a centripetal pattern; in AIDS, such an involvement seems to be more prominent at brain levels following a centrifugal pattern. The central motor conduction time abnormalities and involvement differences of the corticospinal tract of patients with AIDS and HAM/TSP dissected here would allow to re-orient early neurorehabilitation measures in these retroviruses-associated neurodegenerative disorders. Besides this, more sophisticated and sensitive non-invasive corticospinal stimulation measures that detect early changes in thalamocortical-basal ganglia circuitry will be needed in both clinically established as well as asymptomatic patients at times when the fastest corticospinal fibers remain uninvolved.

  16. CERN tours: more popular than ever

    CERN Multimedia

    Anaïs Schaeffer

    2016-01-01

    According to TripAdvisor, CERN is Geneva’s top tourist attraction, welcoming almost 110,000 visitors per year.   The Visits Service received a TripAdvisor Certificate of Excellence for the quality of its tours. From left: Marc Tassera, Carole Ledoux, Vanya Guerre, Bernard Pellequer, Dominique Bertola, Yesika Romand, Chloé Pillonel, Alejandra Lorenzo Gomez. (Image: Jacques Herve Fichet/CERN) Since the start-up of the LHC in 2008 and the discovery of the Higgs boson in 2012, CERN’s visitor numbers have gone through the roof. On 15 July, we hit a record number of 755 visitors in one day (the average is around 400 per day). “This peak can partly be explained by the presence of participants in the International Physics Olympiad,” says Bernard Pellequer, head of the Visitors and Local Engagement section. “A tour of CERN was part of their excursion programme and it was a great pleasure for us to show them around the Laboratory.” But...

  17. A unified grand tour of theoretical physics

    CERN Document Server

    Griffiths, J

    2002-01-01

    Anyone offering a grand tour is faced with several options. Should they concentrate on what may be considered to be essential features, or should they attempt to present a brief glimpse of almost everything? The present offering is a compromise between these two extremes. The area considered - theoretical physics - is now such a vast subject that some kind of compromise is essential. Indeed, the field is now so wide that few could even attempt to review it in a single-authored work. My task here is to assess how well this book has succeeded in its main aim of providing a unified (though introductory) tour of this subject. Constrained within a single volume, this is clearly not an updated Landau-Lifschitz. It cannot be expected to take any particular topic to the level of recent research. Nevertheless, it does seem to cover the broad range of essential topics which now constitute the subject. It starts (most appropriately in my opinion) with geometry. It then covers classical physics, general relativity and qu...

  18. Factors Affecting Healthful Eating Among Touring Popular Musicians and Singers.

    Science.gov (United States)

    Cizek, Erin; Kelly, Patrick; Kress, Kathleen; Mattfeldt-Beman, Mildred

    2016-06-01

    Maintaining good health is essential for touring musicians and singers. The stressful demands of touring may impact food choices, leading to detrimental effects on health and performance. This exploratory pilot study aimed to assess factors affecting healthful eating of touring musicians and singers. A 46-item survey was used to assess food- and nutrition-related attitudes, knowledge and behaviors, and environmental factors, as well as lifestyle, musical background, and demographic data. Participants (n=35) were recruited from a musicians' assistance foundation as well as touring musical theater productions and a music festival. Results indicate that touring musicians and singers had positive attitudes regarding healthful foods. Of 35 respondents, 80.0% indicated eating healthful food was important to them. Respondents reported feeling confident selecting (76.5%) and preparing (82.4%) healthful foods; however, they showed uncertainty when determining if carbohydrate-containing foods should be consumed or avoided. Respondents indicated environmental factors including availability and cost of healthy food options and tour schedules limited access to healthful foods. Venues (73.5%), fast food restaurants (67.6%), and airports (64.7%) were the most frequently identified locations in need of offering more healthful food choices. Respondents (52.9%) indicated more support from others while touring would help them make healthier food choices. More research is needed to develop mobile wellness programs as well as performance-based nutrition guidelines for musicians and singers that address the unique demands associated with touring.

  19. Applicability of BEE requirements for tour operating enterprises in ...

    African Journals Online (AJOL)

    This article focuses on tour operating, one of the key sub-sectors of the tourism industry. The research highlights the profile of tour operating enterprises in South Africa, and evaluates their ability to comply with BEE requirements, as well as the utilization of tourism incentives. Data were collected by questionnaire through a ...

  20. Students as Tour Guides: Innovation in Fieldwork Assessment

    Science.gov (United States)

    Coe, Neil M.; Smyth, Fiona M.

    2010-01-01

    This paper introduces and details an innovative mode of fieldcourse assessment in which students take on the role of tour guides to offer their lecturer and peers a themed, theoretically informed journey through the urban landscape of Havana, Cuba. Informed by notions of student-centered learning and mobile methods, the tour offers an enjoyable,…

  1. Swamp tours in Louisiana post Hurricane Katrina and Hurricane Rita

    Science.gov (United States)

    Dawn J. Schaffer; Craig A. Miller

    2007-01-01

    Hurricanes Katrina and Rita made landfall in southern Louisiana during August and September 2005. Prior to these storms, swamp tours were a growing sector of nature-based tourism that entertained visitors while teaching about local flora, fauna, and culture. This study determined post-hurricane operating status of tours, damage sustained, and repairs made. Differences...

  2. The Mystery Tour; Exploring the Designed Environment with Children.

    Science.gov (United States)

    Balaban, Richard C.; St. Clair, Alison Igo

    The Mystery Tour is a multi-sensory approach to the man-made environment. It is designed to acquaint children with historical significance of buildings and architecture and thus prepare them to participate in decisions concerning historical preservation. Developed through a grant from the national Endowment for the Arts, the Mystery Tour guides…

  3. Exact Solutions to the Double TSP with Multiple Stacks

    DEFF Research Database (Denmark)

    Petersen, Hanne Løhmann; Archetti, Claudia; Madsen, Oli B.G.

    In the Double Travelling Salesman Problem with Multiple Stacks (DTSPMS) a set of orders is given, each one requiring transportation of one item from a customer in a pickup region to a customer in a delivery region. The vehicle available for the transportation in each region carries a container....... We present different modelling approaches to solving the DTSPMS to optimality and use the solutions obtained to evaluate the quality of previously obtained heuristic solutions....

  4. HANFORDS PUBLIC TOUR PROGRAM - AN EXCELLENT EDUCATIONAL TOOL

    Energy Technology Data Exchange (ETDEWEB)

    SINCLAIR KM

    2010-12-07

    Prior to 2001, the Department of Energy (DOE) sponsored limited tours of the Hanford Site for the public, but discontinued the program after the 9/11 terrorist attacks on the U.S. In 2003, DOE's Richland Operations Office (DOE-RL) requested the site's prime contractor to reinstate the public tour program starting in 2004 under strict controls and security requirements. The planning involved a collaborative effort among the security, safety and communications departments of DOE-RL and the site's contracting companies. This paper describes the evolution of, and enhancements to, Hanford's public tours, including the addition of a separate tour program for the B Reactor, the first full-scale nuclear reactor in the world. Topics included in the discussion include the history and growth of the tour program, associated costs, and visitor surveys and assessments.

  5. Hanford's Public Tour Program - An Excellent Educational Tool

    International Nuclear Information System (INIS)

    Sinclair, K.M.

    2010-01-01

    Prior to 2001, the Department of Energy (DOE) sponsored limited tours of the Hanford Site for the public, but discontinued the program after the 9/11 terrorist attacks on the U.S. In 2003, DOE's Richland Operations Office (DOE-RL) requested the site's prime contractor to reinstate the public tour program starting in 2004 under strict controls and security requirements. The planning involved a collaborative effort among the security, safety and communications departments of DOE-RL and the site's contracting companies. This paper describes the evolution of, and enhancements to, Hanford's public tours, including the addition of a separate tour program for the B Reactor, the first full-scale nuclear reactor in the world. Topics included in the discussion include the history and growth of the tour program, associated costs, and visitor surveys and assessments.

  6. The tumor suppressor PTEN inhibits EGF-induced TSP-1 and TIMP-1 expression in FTC-133 thyroid carcinoma cells

    International Nuclear Information System (INIS)

    Soula-Rothhut, Mahdhia; Coissard, Cyrille; Sartelet, Herve; Boudot, Cedric; Bellon, Georges; Martiny, Laurent; Rothhut, Bernard

    2005-01-01

    Thrombospondin-1 (TSP-1) is a multidomain extracellular macromolecule that was first identified as natural modulator of angiogenesis and tumor growth. In the present study, we found that epidermal growth factor (EGF) up-regulated TSP-1 expression in FTC-133 (primary tumor) but not in FTC-238 (lung metastasis) thyroid cancer cells. Both EGF and TSP-1 induced expression of tissue inhibitor of metalloproteinase-1 (TIMP-1) in a mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) and phosphatidylinositol 3-kinase (PI3-kinase)-dependent manner. In FTC-133 cells, EGF induced proliferation in a TSP-1- and TIMP-1-dependent manner. In addition, we determined that re-expression of the tumor suppressor protein PTEN induced cell death, an effect that correlated with a block of Akt kinase phosphorylation. EGF-induced TSP-1 and TIMP-1 promoter activity and protein expression were inhibited in FTC-133 cells stably expressing wtPTEN but not in cells expressing mutant PTEN. Furthermore, we found that wtPTEN inhibited EGF-but not TSP-1-stimulated FTC-133 cell migration and also inhibited invasion induced by EGF and by TSP-1. Finally, an antibody against TSP-1 reversed EGF-stimulated FTC-133 cell invasion as well as the constitutive invasive potential of FTC-238 cells. Overall, our results suggest that PTEN can function as an important modulator of extracellular matrix proteins in thyroid cancer. Therefore, analyzing differential regulation of TSP-1 by growth factors such as EGF can be helpful in understanding thyroid cancer development

  7. WE-C-TOUR-I-00: Exhibit Hall Guided Tours-Dosimters for QC in Diagnostic Imaging (Wednesday)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2016-06-15

    Tour Leader: Xia Jiang, Ohio State University, Columbus, OH Tour Guides: Xia Jiang, Ohio State University, Columbus, OH Kevin Little, The University of Chicago, Chicago, IL Adrien Sanchez, University of Chicago, Chicago, IL Participating Vendors: IBA PTW - New York Radcal Corporation RTI Electronics, Inc. Exhibit Hall Guided Tours is a new program launching this year at the Annual Meeting. The Guided Tours are designed to enhance the interaction between meeting attendees and exhibitors. This year’s Imaging Guided Tours are organized around the theme of dosimeters for quality control in diagnostic imaging. Tours will begin with an introduction and background given by Dr. Xia Jiang, the Tour Leader. The introduction will cover the types and properties of different radiation dosimeters used for quality assurance in clinical radiology. Attendees will then break into smaller groups, each lead by an AAPM-member Tour Guide. The tour groups will visit the exhibit booths of vendors who provide appropriate dosimeters, and a vendor representative will give a presentation to the group about their particular product(s). The vendor representatives as well as the Tour Guides will be available to answer questions. Outline: Types and properties of radiation detectors and dosimeters Ionization chamber dosimeters Solid state dosimeters Dosimeter calibration: Primary and secondary standards dosimetry laboratories Instruments for measuring tube voltage and exposure time Vendor presentations will likely cover features and innovations of different dosimeter systems, as well as their practical use. Learning Objectives: Understand the types and properties of different instrumentations used for quality control in diagnostic imaging. Understand the process of dosimeter calibration. Gain familiarity with the latest commercial dosimeter systems from different vendors.

  8. WE-C-TOUR-I-00: Exhibit Hall Guided Tours-Dosimters for QC in Diagnostic Imaging (Wednesday)

    International Nuclear Information System (INIS)

    2016-01-01

    Tour Leader: Xia Jiang, Ohio State University, Columbus, OH Tour Guides: Xia Jiang, Ohio State University, Columbus, OH Kevin Little, The University of Chicago, Chicago, IL Adrien Sanchez, University of Chicago, Chicago, IL Participating Vendors: IBA PTW - New York Radcal Corporation RTI Electronics, Inc. Exhibit Hall Guided Tours is a new program launching this year at the Annual Meeting. The Guided Tours are designed to enhance the interaction between meeting attendees and exhibitors. This year’s Imaging Guided Tours are organized around the theme of dosimeters for quality control in diagnostic imaging. Tours will begin with an introduction and background given by Dr. Xia Jiang, the Tour Leader. The introduction will cover the types and properties of different radiation dosimeters used for quality assurance in clinical radiology. Attendees will then break into smaller groups, each lead by an AAPM-member Tour Guide. The tour groups will visit the exhibit booths of vendors who provide appropriate dosimeters, and a vendor representative will give a presentation to the group about their particular product(s). The vendor representatives as well as the Tour Guides will be available to answer questions. Outline: Types and properties of radiation detectors and dosimeters Ionization chamber dosimeters Solid state dosimeters Dosimeter calibration: Primary and secondary standards dosimetry laboratories Instruments for measuring tube voltage and exposure time Vendor presentations will likely cover features and innovations of different dosimeter systems, as well as their practical use. Learning Objectives: Understand the types and properties of different instrumentations used for quality control in diagnostic imaging. Understand the process of dosimeter calibration. Gain familiarity with the latest commercial dosimeter systems from different vendors.

  9. TU-E-TOUR-I-00: Exhibit Hall Guided Tours-Dosimters for QC in Diagnostic Imaging (Tuesday)

    International Nuclear Information System (INIS)

    2016-01-01

    Tour Leader: Xia Jiang, Ohio State University, Columbus, OH Tour Guides: Xia Jiang, Ohio State University, Columbus, OH Kevin Little, The University of Chicago, Chicago, IL Christina Sammet, Lurie Children’s Hospital of Chicago, Chicago, IL Participating Vendors: IBA PTW - New York Radcal Corporation RTI Electronics, Inc. Exhibit Hall Guided Tours is a new program launching this year at the Annual Meeting. The Guided Tours are designed to enhance the interaction between meeting attendees and exhibitors. This year’s Imaging Guided Tours are organized around the theme of dosimeters for quality control in diagnostic imaging. Tours will begin with an introduction and background given by Dr. Xia Jiang, the Tour Leader. The introduction will cover the types and properties of different radiation dosimeters used for quality assurance in clinical radiology. Attendees will then break into smaller groups, each lead by an AAPM-member Tour Guide. The tour groups will visit the exhibit booths of vendors who provide appropriate dosimeters, and a vendor representative will give a presentation to the group about their particular product(s). The vendor representatives as well as the Tour Guides will be available to answer questions. Outline: Types and properties of radiation detectors and dosimeters Ionization chamber dosimeters Solid state dosimeters Dosimeter calibration: Primary and secondary standards dosimetry laboratories Instruments for measuring tube voltage and exposure time Vendor presentations will likely cover features and innovations of different dosimeter systems, as well as their practical use. Learning Objectives: Understand the types and properties of different instrumentations used for quality control in diagnostic imaging. Understand the process of dosimeter calibration. Gain familiarity with the latest commercial dosimeter systems from different vendors.

  10. TU-E-TOUR-I-00: Exhibit Hall Guided Tours-Dosimters for QC in Diagnostic Imaging (Tuesday)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2016-06-15

    Tour Leader: Xia Jiang, Ohio State University, Columbus, OH Tour Guides: Xia Jiang, Ohio State University, Columbus, OH Kevin Little, The University of Chicago, Chicago, IL Christina Sammet, Lurie Children’s Hospital of Chicago, Chicago, IL Participating Vendors: IBA PTW - New York Radcal Corporation RTI Electronics, Inc. Exhibit Hall Guided Tours is a new program launching this year at the Annual Meeting. The Guided Tours are designed to enhance the interaction between meeting attendees and exhibitors. This year’s Imaging Guided Tours are organized around the theme of dosimeters for quality control in diagnostic imaging. Tours will begin with an introduction and background given by Dr. Xia Jiang, the Tour Leader. The introduction will cover the types and properties of different radiation dosimeters used for quality assurance in clinical radiology. Attendees will then break into smaller groups, each lead by an AAPM-member Tour Guide. The tour groups will visit the exhibit booths of vendors who provide appropriate dosimeters, and a vendor representative will give a presentation to the group about their particular product(s). The vendor representatives as well as the Tour Guides will be available to answer questions. Outline: Types and properties of radiation detectors and dosimeters Ionization chamber dosimeters Solid state dosimeters Dosimeter calibration: Primary and secondary standards dosimetry laboratories Instruments for measuring tube voltage and exposure time Vendor presentations will likely cover features and innovations of different dosimeter systems, as well as their practical use. Learning Objectives: Understand the types and properties of different instrumentations used for quality control in diagnostic imaging. Understand the process of dosimeter calibration. Gain familiarity with the latest commercial dosimeter systems from different vendors.

  11. The Greening Role of Tour Operators

    Science.gov (United States)

    Lozano, Javier; Arbulú, Italo; Rey-Maquieira, Javier

    2016-01-01

    This paper shows that the tour operators (TOs) can play a coordinating role in the adoption of environmental management upstream the tourism supply chain. This is done using a dynamic model to analyze the environmental management adoption by hotels in a tourism destination induced by a TO. The TO can create incentives to greening hotels' management through the sharing of an environmental price premium. We show that the extent of green management adoption depends on interest rate, the willingness to pay for environmental quality, and hotels' organizational inertia. We also show how the financial yields from green management are shared between TOs and hotels. Finally, we consider a destination manager that subsidizes hotels' green management. If the destination manager does not take the greening role of TOs into account, she could mistake the true trade-off that she faces between the destination's economic and environmental outcomes for the win-win setting that characterizes the general problem.

  12. Tour guides developing urban ecotourism destinations

    DEFF Research Database (Denmark)

    Meged, Jane Widtfeldt; Lasa-Gonzalez, Anne Cecilie

    is “controlled by other stakeholder and largely beyond the influence of tour guides” (ibid). In fact Weiler and Black (2015) argue that pathways and extend have never been investigated on how interpretative guiding improves the economic viability and competitiveness of business, and social and cultural benefits...... to local communities and destinations. In this paper, we want to propose a research agenda where guides have a central role in cooperation with public and private key stakeholder in development of a scalable participatory model for sustainable urban ecotourism. Wang & Wang (2013) define urban ecotourism...... as an “activity system to satisfy needs of the locals and visitors for using local natural scenery, culture and folk customs, and also to maintain ecological balance of urban environment and establish environment-friendly concepts” (2013:1). Drawing on Iterative Participatory Design, where “the concept is defined...

  13. Landscapes of Mars A Visual Tour

    CERN Document Server

    Vogt, Gregory L

    2008-01-01

    Landscapes of Mars is essentially a picture book that provides a visual tour of Mars. All the major regions and topographical features will be shown and supplemented with chapter introductions and extended captions. In a way, think of it as a visual tourist guide. Other topics covered are Martian uplands on the order of the elevation of Mt. Everest, Giant volcanoes and a rift system, the Grand Canyon of Mars, craters and the absence of craters over large regions (erosion), and wind shadows around craters, sand dunes, and dust devils. The book includes discussions on the search for water (braided channels, seepage, sedimentary layering, etc.) as well as on the Viking mission search for life, Mars meteorite fossil bacteria controversy, and planetary protection in future missions. The book concludes with an exciting gallery of the best 3D images of Mars making the book a perfect tool for understanding Mars and its place in the solar system.

  14. Structural and electrical characterization of tamarind seed polysaccharide (TSP) doped with NH4HCO2

    Science.gov (United States)

    Premalatha, M.; Mathavan, T.; Selvasekarapandian, S.; Selvalakshmi, S.

    2018-04-01

    In the modern era, development of electrochemical energy devices such as batteries, fuel cells and supercapacitors gain attention due to the deficiency of renewable energy resources. More specifically, proton conducting materials create prime interest in the development of electrochemical devices. In this regards, a novel proton conducting biopolymer electrolyte based on Tamarind Seed Polysaccharide (TSP) was synthesized with different concentration of ammonium formate (NH4HCO2). The amorphous nature of the polymer electrolytes has been identified by XRD technique. The observed ionic conductivity values reveal that the biopolymer containing 1 g TSP: 0.4 g NH4HCO2 has highest ionic conductivity 1.23×10-3 S cm-1.

  15. Data-Acquisition Software for PSP/TSP Wind-Tunnel Cameras

    Science.gov (United States)

    Amer, Tahani R.; Goad, William K.

    2005-01-01

    Wing-Viewer is a computer program for acquisition and reduction of image data acquired by any of five different scientificgrade commercial electronic cameras used at Langley Research center to observe wind-tunnel models coated with pressure or temperature-sensitive paints (PSP/TSP). Wing-Viewer provides full automation of camera operation and acquisition of image data, and has limited data-preprocessing capability for quick viewing of the results of PSP/TSP test images. Wing- Viewer satisfies a requirement for a standard interface between all the cameras and a single personal computer: Written by use of Microsoft Visual C++ and the Microsoft Foundation Class Library as a framework, Wing-Viewer has the ability to communicate with the C/C++ software libraries that run on the controller circuit cards of all five cameras.

  16. Characterization, source identification and apportionment of selected metals in TSP in an urban atmosphere.

    Science.gov (United States)

    Shah, Munir H; Shaheen, N; Jaffar, M

    2006-03-01

    To understand the metal distribution characteristics in the atmosphere of urban Islamabad, total suspended particulate (TSP) samples were collected on daily 12 h basis, at Quaid-i-Azam University campus, using high volume sampler. The TSP samples were treated with HNO(3)/HClO(4) based wet digestion method for the quantification of eight selected metals; Fe, Zn, Pb, Mn, Cr, Co, Ni and Cd by FAAS method. The monitoring period ran from June 2001 to January 2002, with a total of 194 samples collected on cellulose filters. Effects of different meteorological conditions such as temperature, relative humidity, wind speed and wind direction on selected metal levels were interpreted by means of multivariate statistical approach. Enhanced metal levels for Fe (930 ng/m(3)), Zn (542 ng/m(3)) and Pb (210 ng/m(3)) were found on the mean scale while Mn, Cr, Co and Ni emerged as minor contributors. Statistical correlation study was also conducted and a strong correlation was observed between Pb-Cr (r=0.611). The relative humidity showed some significant influence on atmospheric metal distribution while other meteorological parameters showed weak relationship with TSP metal levels. Regarding the origin of sources of heavy metals in TSP, the statistical procedure identified three source profiles; automobile emissions, industrial/metallurgical units, and natural soil dust. The metal levels were also compared with those reported for other parts of the world which showed that the metal levels in urban atmosphere of Islamabad are in exceedence than those of European industrial and urban sites while comparable with some Asian sites.

  17. Experimental and numerical study of deposit formation in secondary side SG TSP by electrokinetic approach

    International Nuclear Information System (INIS)

    Guillodo, Michael; Foucault, Marc; Ryckelynck, Natacha; Chahma, Farah; Guingo, Mathieu; Mansour, Carine; Alos-Ramos, Olga; Corredera, Geraldine

    2012-09-01

    Corrosion products deposit formation observed in PWR steam generators (SGs) - related to SG free span fouling and SG clogging - is now reported since several years. SG clogging is a localized phenomenon observed between the leading edge of the Tube Support Plate (TSP) and SG tubing materials. Based on visual inspections, it was found that the gaps between SG tubing material and TSP at the lower part of the broached holes were getting progressively blocked. Therefore, for safe operation, most affected PWRs had to be operated at reduced power. TSP blockage was mainly observed for low-pH water chemistry conditioning, which directly depends on the operating water chemistry. The TSP blockage mechanism is complex due to the localized conditions in which flow pattern change, chemistry and electrochemical conditions are not well understood. Electrokinetic considerations could be pointed out to explain the coupling of chemistry, materials and thermohydraulic (T/H) conditions. In this frame AREVA and EDF have launched a long-term R and D program in order to understand the mechanisms driving the formation of SG clogging. This study based on parametric laboratory tests aims to assess the role of secondary water chemistry, material and T/H conditions on deposit formation. The experimental approach focused on electrokinetic measurements of metallic substrates and on the assessment of oxidation properties of materials in secondary side chemistry. An overall analysis of recent results is presented to address SG deposit formation in secondary water chemistry for various conditioning amines - morpholine, ethanolamine and dimethylamine. To complete the study, the experimental results have been correlated to CFD simulations of particle deposition, by means of stochastic Lagrangian models. These calculations have in particular reproduced correctly the location of the most important particle deposit (the leading edge of the test tube), and have stressed the influence of the

  18. Measurement of Ambient Air Particle (TSP, PM10, PM2,5) Around Candidate Location of PLTN Semenanjung Lemahabang

    International Nuclear Information System (INIS)

    AgusGindo S; Budi Hari H

    2008-01-01

    Measurement analysis of ambient air particle (TSP, PM 10 , PM 2,5 ) around location candidate of PLTN (Power Station of Nuclear Energy) Semenanjung Lemahabang has been carried out. The measurement was conducted in May 2007 with a purpose to providing information about concentration of ambient air particle (TSP, PM 10 , PM 2,5 ) and diameter distribution of its air particle. The measurement was conducted in three locations i.e. 1). Balong village 2). Bayuran 3). Bondo. Concentration of TSP, PM 10 , and PM 2,5 per 24 hours in all measured locations in area candidate of PLTN exceed quality standard of national ambient air is specified by government. All measurement locations for the TSP, PM 10 , and PM 2,5 was include category of ISPU (Standard Index of Air Pollution) moderate. (author)

  19. Fast-response underwater TSP investigation of subcritical instabilities of a cylinder in crossflow

    Science.gov (United States)

    Capone, Alessandro; Klein, Christian; Di Felice, Fabio; Beifuss, Uwe; Miozzi, Massimo

    2015-10-01

    We investigate the classic cylinder in crossflow case to test the effectiveness of a fast-response underwater temperature-sensitive paint coating (TSP) in providing highly resolved spatial and time observations of the action of a flow over a bluff body surface. The flow is investigated at Reynolds number crisis state. The obtained TSP image sequences convey an accurate description of the evolution of the main features in the fluid-cylinder interaction, like the separation line position, the pattern of the large coherent structures acting on the cylinder's surface and the small-scale intermittent streamwise arrays of vortices. Ad hoc data management and features extraction techniques are proposed which allow extraction of quantitative data, such as separation line position and vortex-shedding frequency, and results are compared to the literature. Use of TSP for water applications introduces an interesting point of view about the fluid-body interactions by focusing directly on the effect of the flow on the model surface.

  20. Angiogenesis in cancer of unknown primary: clinicopathological study of CD34, VEGF and TSP-1

    International Nuclear Information System (INIS)

    Karavasilis, Vasilis; Malamou-Mitsi, Vasiliki; Briasoulis, Evangelos; Tsanou, Elena; Kitsou, Evangelia; Kalofonos, Haralambos; Fountzilas, George; Fotsis, Theodore; Pavlidis, Nicholas

    2005-01-01

    Cancer of unknown primary remains a mallignancy of elusive biology and grim prognosis that lacks effective therapeutic options. We investigated angiogenesis in cancer of unknown primary to expand our knowledge on the biology of these tumors and identify potential therapeutic targets. Paraffin embedded archival material from 81 patients diagnosed with CUP was used. Tumor histology was adenocarcinoma (77%), undifferentiated carcinoma (18%) and squamous cell carcinoma (5%). The tissue expression of CD34, VEGF and TSP-1 was assessed immunohistochemically by use of specific monoclonal antibodies and was analyzed against clinicopathological data. VEGF expression was detected in all cases and was strong in 83%. Stromal expression of TSP-1 was seen in 80% of cases and was strong in 20%. The expression of both proteins was not associated with any clinical or pathological parameters. Tumor MVD was higher in tumors classified as unfavorable compared to more favorable and was positively associated with VEGF and negatively with TSP-1. Angiogenesis is very active and expression of VEGF is almost universal in cancers of unknown primary. These findings support the clinical investigation of VEGF targeted therapy in this clinical setting

  1. Land reclamation on the Nevada Test Site: A field tour

    International Nuclear Information System (INIS)

    Winkel, V.K.; Ostler, W.K.

    1993-01-01

    An all-day tour to observe and land reclamation on the Nevada Test Site was conducted in conjunction with the 8th Wildland Shrub and Arid Land Restoration Symposium. Tour participants were introduced to the US Department of Energy reclamation programs for Yucca Mountain Site Characterization Project and Treatability Studies for Soil Media (TSSM) Project. The tour consisted of several stops that covered a variety of topics and studies including revegetation by seeding, topsoil stockpile stabilization, erosion control, shrub transplanting, shrub herbivory, irrigation, mulching, water harvesting, and weather monitoring

  2. The matricellular protein TSP1 promotes human and mouse endothelial cell senescence through CD47 and Nox1.

    Science.gov (United States)

    Meijles, Daniel N; Sahoo, Sanghamitra; Al Ghouleh, Imad; Amaral, Jefferson H; Bienes-Martinez, Raquel; Knupp, Heather E; Attaran, Shireen; Sembrat, John C; Nouraie, Seyed M; Rojas, Mauricio M; Novelli, Enrico M; Gladwin, Mark T; Isenberg, Jeffrey S; Cifuentes-Pagano, Eugenia; Pagano, Patrick J

    2017-10-17

    Senescent cells withdraw from the cell cycle and do not proliferate. The prevalence of senescent compared to normally functioning parenchymal cells increases with age, impairing tissue and organ homeostasis. A contentious principle governing this process has been the redox theory of aging. We linked matricellular protein thrombospondin 1 (TSP1) and its receptor CD47 to the activation of NADPH oxidase 1 (Nox1), but not of the other closely related Nox isoforms, and associated oxidative stress, and to senescence in human cells and aged tissue. In human endothelial cells, TSP1 promoted senescence and attenuated cell cycle progression and proliferation. At the molecular level, TSP1 increased Nox1-dependent generation of reactive oxygen species (ROS), leading to the increased abundance of the transcription factor p53. p53 mediated a DNA damage response that led to senescence through Rb and p21 cip , both of which inhibit cell cycle progression. Nox1 inhibition blocked the ability of TSP1 to increase p53 nuclear localization and p21 cip abundance and its ability to promote senescence. Mice lacking TSP1 showed decreases in ROS production, p21 cip expression, p53 activity, and aging-induced senescence. Conversely, lung tissue from aging humans displayed increases in the abundance of vascular TSP1, Nox1, p53, and p21 cip Finally, genetic ablation or pharmacological blockade of Nox1 in human endothelial cells attenuated TSP1-mediated ROS generation, restored cell cycle progression, and protected against senescence. Together, our results provide insights into the functional interplay between TSP1 and Nox1 in the regulation of endothelial senescence and suggest potential targets for controlling the aging process at the molecular level. Copyright © 2017 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

  3. EDF steam generators fleet: In-operation monitoring of TSP blockage and tube fouling

    Energy Technology Data Exchange (ETDEWEB)

    Bertrand, P.; Gay, N.; Crinon, R. [Electricite De France (France)

    2012-07-01

    EDF operates 58 Pressurized Water Reactors in France. In the mid 2000‟s some of them have been affected by Steam Generators (SG) Tube Support Plates (TSP) blockage and U-tubes external surface fouling with iron oxides deposits due to corrosion of secondary-side components. These issues have been tackled by a global maintenance strategy of chemical cleanings and a method for in-operation monitoring of fouling and TSP blockage has been developed and is implemented since mid 2009. This monitoring is aimed at giving information for SG maintenance planning as regards non destructive examinations and chemical cleaning. This paper will first remind of the physical reasons of fouling and TSP blockage and identify the resulting stakes regarding safety and availability along with the action levers available to control both phenomena. Then details will be given on how in-operation monitoring of fouling and TSP blockage is carried out, using measurements of Wide Range water Level (WRL) and SG steam pressure during thermally stabilized periods. Information will also be given on how those data are analyzed and shared as well at a local as at a corporate level to participate in the planning of SG inspection and maintenance operations. Finally, possible refinements will be discussed, notably regarding the issue of WRL measurements reliability and the possibility to use the analysis of SG dynamic behavior during power transients to assess the TSP blockage ratio. In terms of „issues requiring discussion‟, the following are operational issues currently being investigated by EDF: 1. SG pressure can have quite large variations during one operating cycle (notably after a plant trip) and from one cycle to the other and generally pressure tends to decrease on a long-term basis. How can such variations be explained? What are the solutions to moderate/stop the pressure loss? 2. On some of the SG-models operated by EDF, hard curative Chemical Cleaning of the U-tubes didn't bring

  4. Accelerating ROP detector layout optimization

    International Nuclear Information System (INIS)

    Kastanya, D.; Fodor, B.

    2012-01-01

    The ADORE (Alternating Detector layout Optimization for REgional overpower protection system) algorithm for performing the optimization of regional overpower protection (ROP) system for CANDU® reactors have been recently developed. The simulated annealing (SA) stochastic optimization technique is utilized to come up with a quasi optimized detector layout for the ROP systems. Within each simulated annealing history, the objective function is calculated as a function of the trip set point (TSP) corresponding to the detector layout for that particular history. The evaluation of the TSP is done probabilistically using the ROVER-F code. Since during each optimization execution thousands of candidate detector layouts are evaluated, the overall optimization process is time consuming. Since for each ROVER-F evaluation the number of fuelling ripples controls the execution time, reducing the number of fuelling ripples used during the calculation of TSP will reduce the overall optimization execution time. This approach has been investigated and the results are presented in this paper. The challenge is to construct a set of representative fuelling ripples which will significantly speedup the optimization process while guaranteeing that the resulting detector layout has similar quality to the ones produced when the complete set of fuelling ripples is employed. Results presented in this paper indicate that a speedup of up to around 40 times is attainable when this approach is utilized. (author)

  5. Review of Tour of the Nile [iPad App

    Directory of Open Access Journals (Sweden)

    Helen Strudwick

    2013-07-01

    Full Text Available A review of the iPad app, Tour of the Nile. The app promises 'a virtual journey along the Nile Valley' plus the chance to 'handle' objects through the technology of augmented reality.

  6. Exercise intensity of cycle-touring events.

    Science.gov (United States)

    Neumayr, G; Pfister, R; Mitterbauer, G; Gaenzer, H; Sturm, W; Eibl, G; Hoertnagl, H

    2002-10-01

    The aim of the study was to analyze the exercise intensity of recreational cyclists participating in a cycling-touring event. In 14 male healthy recreational cyclists heart rate (HR) monitoring was performed during the Otztal Radmarathon 1999 (distance: 230 km; altitude difference: 5500 m) in order to evaluate the HR response and to estimate the cardiopulmonary strains for the less-trained athlete confronted with such a marathon. Four different exercise intensities were defined as percentages of maximal HR (HR(max)) as follows: recovery HR (HR(re)) 90 %. All athletes finished the competition successfully. The mean racing time was 10 h 14 min, the average speed 22.5 km/h. The mean HR(max) was 188 bpm, the average value of the measured HRs (HR(average)) was 145 bpm resulting in a mean HR(average)/HR(max) ratio of 0.77. Athletes spent 18.5 % (1 h 54 min) of total race time within HR(re), 28 % (2 h 52 min) within HR(ma), 39.5 % (4 h 02 min) within HR(ia), and 14 % (1 h 26 min) within HR(an). The vast majority of exercise was done under "aerobic conditions" (HR(re) + HR(ma) + HR(ia) = 86 % or 8 h 48 min) - confirming the knowledge that the aerobic energy supply is crucial for the performance of long-term exercise. The large amount of high exercise intensities (HR(ia) + HR(an) = 53.5 % or 5 h 30 min), however, features the intense cardiopulmonary strains evoked by such competitions. The HR response was related to the course profile with HRs significantly declining in all subjects to an extent of 10 % during the course of race. Our findings show that the exercise intensity borne by recreational cyclists during a cycle-touring event is high and very similar to that of professionals. With respect to the high cardiovascular strains a thorough medical screening is advisable for any participant of such an event combining both high volume and high intensity loads.

  7. Deferensifikasi Dan Diversifikasi Produk Dalam Pengembangan Produk Tour Bpw

    OpenAIRE

    Rachmadi, Hari

    2008-01-01

    The meaning of diversification and diferensification product is to make a product with kinds of variety subject and other subyek (tourism object). Fasility or service so it look all product have her own specialization the is sport, cultural, and adventure so it make more kinds of interesting product. The diversification and deferensification product is useful to increase service and sales tour package in travel agent, because that can make change at tour package more variety and more int...

  8. LAFD: TA-55 General Facility Familiarization Tour, Course #55261

    Energy Technology Data Exchange (ETDEWEB)

    Rutherford, Victor Stephen [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Miller, Joshua [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Mason, Robert Clifford [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2018-01-10

    Los Alamos National Laboratory (LANL) will conduct familiarization tours for personnel of the Los Alamos County Fire Department (LAFD) at the TA-55 General Facility. These familiarization tours are official LANL business; the purpose of these tours is to orient LAFD firefighters to the facility so that they can respond efficiently and quickly to a variety of emergency situations. This orientation includes, among other topics, ingress and egress of the area and buildings, layout and organization of the facility, evacuation procedures and assembly points, and areas of concern within the various buildings at the facility. LAFD firefighters have the skills and abilities to perform firefighting operations and other emergency response tasks that cannot be provided by LANL personnel who have the required clearance level. This handout provides details of the information, along with maps and diagrams, to be presented during the familiarization tours. The handout will be distributed to the trainees at the time of the tour. A corresponding checklist will also be used as guidance during the familiarization tours to ensure that all required information is presented to LAFD personnel.

  9. LAFD: TA-3 NISC & SCC Facility Familiarization Tour, OJT #53356

    Energy Technology Data Exchange (ETDEWEB)

    Rutherford, Victor Stephen [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Norman, Rich [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Montoya, Gene [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Blumberg, Paul A. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); McCurdy, Patrick B. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-10-24

    Los Alamos National Laboratory (LANL, the Laboratory, or the Lab) conducts familiarization tours for Los Alamos County Fire Department (LAFD) personnel at the Strategic Computing Complex (SCC), TA-03-2327, and the Nonproliferation & International Security Complex (NISC), TA-03-2322. These tours are official LANL business; their purpose is to orient the firefighters to the SCC and the NISC so that they can respond efficiently and quickly to a variety of emergency situations. The tour includes ingress and egress of the buildings, layout and organization of the buildings, evacuation procedures, and areas of concern to emergency responders within these buildings. LAFD firefighters have the training, skills, and abilities to perform these emergency responder tasks; other LANL personnel who have the required clearance level cannot perform these tasks. This handout provides details of the information, along with maps and diagrams, to be presented during the familiarization tours. The report will be distributed to the trainees at the time of the tour. A corresponding checklist will also be used as guidance during the familiarization tours to ensure that all required information is presented to the LAFD personnel.

  10. LAFD: TA-16 HE Facility Familiarization Tour, OJT 55258

    Energy Technology Data Exchange (ETDEWEB)

    Rutherford, Victor Stephen [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-05-31

    Los Alamos National Laboratory (LANL) will conduct familiarization tours for personnel of the Los Alamos County Fire Department (LAFD) at TA-16 high explosives (HE) facilities. These familiarization tours are official LANL business; the purpose of these tours is to orient LAFD firefighters to the facility so that they can respond efficiently and quickly to a variety of emergency situations. This orientation includes, among other topics, ingress and egress of the area and buildings, layout and organization of the facility, evacuation procedures and assembly points, and areas of concern within the various buildings at the facility. LAFD firefighters have the skills and abilities to perform firefighting operations and other emergency response tasks that cannot be provided by LANL personnel who have the required clearance. This handout provides details of the information, along with maps and diagrams, to be presented during the familiarization tours. The handout will be distributed to the trainees at the time of the tour. A corresponding checklist will also be used as guidance during the familiarization tours to ensure that all required information is presented to LAFD personnel.

  11. WE-C-TOUR-T-00: Exhibit Hall Guided Tours-Microdosimeters for Therapy (Wednesday) WE-C-TOUR-T-01

    International Nuclear Information System (INIS)

    2016-01-01

    Tour Leader: Indra Das, NYU Langone Medical Center, New York, NY Tour Guides: Hsui Ai, Indiana University School of Medicine, Indianapolis, IN Paulina Galvis, NYU Langone Medical Center, New York, NY Olga Volotoskova, NYU Langone Medical Center, New York, NY Participating Vendors: IBA PTW – New York RTI Electronics, Inc. Standard Imaging, Inc. Sun Nuclear Corporation Small fields are increasing used in specialized radiation treatments such as Gammaknife, Cyberknife, Tomotherapy, IMRT, VMAT, SRS and SBRT. Due to small field size electron transport creates lateral electronic disequilibrium and thus dosimetry could be very difficult. Microdetectors are used for small field dosimetry which will be discussed in preface of this tour as below: Understanding small field e.g. meaning and definition of small field IAEA definition and approach Characteristics of microdetectors in terms of perturbation, recombination, correction Suitability of microdetectors in small field dosimetry

  12. Insecure positions, heteronomous autonomy and tourism-cultural capital: a Bourdieusian reading of tour guides on BBC Worldwide's Doctor Who Experience Walking Tour

    OpenAIRE

    Garner, Ross

    2017-01-01

    This article contributes towards debates concerning media tourism and tour guiding by using Pierre Bourdieu’s (1993) arguments regarding field and capital to analyse performed tour guide identities on BBC Worldwide’s Doctor Who Experience Walking Tour in Cardiff Bay. The article pursues three core arguments: firstly, that a Bourdieusian framework provides an enhanced understanding of the insecure positions that tour guides occupy in what is referred to throughout as the tourism field. Secondl...

  13. LINAC4 takes a tour of Europe

    CERN Multimedia

    Katarina Anthony

    2011-01-01

    Along the German Autobahnen, a truck carrying 20 tonnes of copper is on its way to Poland. The metal has already made a short tour of Europe, yet the drive across the high-speed highway is only the beginning of its transformation into CERN’s next linear accelerator, LINAC4.   Grzegorz Wrochna (left), director of the Andrzej Soltan Institute for Nuclear Studies (IPJ), and Rolf Heuer (right), CERN DG, sign the framework agreement between the two institutes. By the summer of 2012, the PI-Mode Structures (PIMS) will be constructed and completely installed in the LINAC4 tunnel. The PIMS cavities are the final accelerating structures needed for LINAC4, and have been designed to accelerate protons from 100 to 160MeV. While the first cavity was built entirely at CERN, construction of the remaining cavities has become a larger, multi-national operation. In a 1 million euro framework agreement signed on 11 February by the Director-General, the Andrzej Soltan Institute for Nuclear Studies in Swie...

  14. Deep sky observing an astronomical tour

    CERN Document Server

    Coe, Steven R

    2016-01-01

    This updated second edition has all of the information needed for your successful forays into deep sky observing. Coe uses his years of experience to give detailed practical advice about how to find the best observing site, how to make the most of the time spent there, and what equipment and instruments to take along. There are comprehensive lists of deep sky objects of all kinds, along with Steve's own observations describing how they look through telescopes with apertures ranging from 4 inches to 36 inches (0.1 - 0.9 meters). Binocular observing also gets its due, while the lists of objects have been amended to highlight only the best targets. A new index makes finding targets easier than ever before, while the selection of viewing targets has been revised from the first edition. Most of all, this book is all about how to enjoy astronomy. The author's enthusiasm and sense of wonder shine through every page as he invites you along on a tour of some of the most beautiful and fascinating sites in the deep ...

  15. The Chemical Cosmos A Guided Tour

    CERN Document Server

    Miller, Steve

    2012-01-01

    If you have ever wondered how we get from the awesome impersonality of the Big Bang universe to the point where living creatures can start to form, and evolve into beings like you, your friends and your family, wonder no more. Steve Miller provides us with a tour through the chemical evolution of the universe, from the formation of the first molecules all the way to the chemicals required for life to evolve. Using a simple Hydrogen molecule – known as H-three-plus - as a guide, he takes us on a journey that starts with the birth of the first stars, and how, in dying, they pour their hearts out into enriching the universe in which we live. Our molecular guide makes its first appearance at the source of the Chemical Cosmos, at a time when only three elements and a total of 11 molecules existed. From those simple beginnings, H-three-plus guides us down river on the violent currents of exploding stars, through the streams of the Interstellar Medium, and into the delta where new stars and planets form. We are fi...

  16. Supertramp (de)tour to CERN

    CERN Multimedia

    Francesco Poppi

    2010-01-01

    During their recent European tour celebrating forty years since their debut album, the members of the famous British rock-band Supertramp decided to take a break and pay a visit to CERN on 16 October, the day after their concert at Geneva Arena. It was a fast break for the authors of the popular “Breakfast in America”, as their next concert was in Lyon the same evening.   Supertramp's John Helliwell with anti-matter trap. Not content with merely unveiling the mysteries of the Universe, CERN has also been able to improve the performance of one of the world's most famous singers and saxophonists, John Helliwell, the leader of the rock band Supertramp! In his words: “Tonight in Lyon I shall play the saxophone better than before I came here”. And Gabe Dixon, keyboard player and songwriter, added: “I would love to write a song about the Universe now. If only I could put all this into poetic words…that would be a real accomplishment&rdqu...

  17. Welcome to the Universe an astrophysical tour

    CERN Document Server

    DeGrasse Tyson, Neil; Gott, Richard J

    2016-01-01

    Welcome to the Universe is a personal guided tour of the cosmos by three of today's leading astrophysicists. Inspired by the enormously popular introductory astronomy course that Neil deGrasse Tyson, Michael A. Strauss, and J. Richard Gott taught together at Princeton, this book covers it all--from planets, stars, and galaxies to black holes, wormholes, and time travel. Describing the latest discoveries in astrophysics, the informative and entertaining narrative propels you from our home solar system to the outermost frontiers of space. How do stars live and die? Why did Pluto lose its planetary status? What are the prospects of intelligent life elsewhere in the universe? How did the universe begin? Why is it expanding and why is its expansion accelerating? Is our universe alone or part of an infinite multiverse? Answering these and many other questions, the authors open your eyes to the wonders of the cosmos, sharing their knowledge of how the universe works. Breathtaking in scope and stunningly illustrate...

  18. Strategi Pengembangan Objek Wisata Loko Tour Dan Objek Wisata Geologi Sebagai Wisata Edukasi Di Kabupaten Blora

    OpenAIRE

    Putranto, Rony Ardian; Widayati, Wiwik; Sulistyowati

    2015-01-01

    This research aims to find out potential tourism objects which located in Blora, they are Loco Tour and Geology. Besides having a vacation there, visitors can also learn something new from each object there. Blora local Government doesn't optimally mange these tourism objects yet, however these can be attraction to get people to come. These tourism objects are not well managed, and people don't even realize the existence of these objects and. Therefore, this study aims to determine the best s...

  19. Standardisation of Western blotting to detect HTLV-1 antibodies synthesised in the central nervous system of HAM/TSP patients

    Directory of Open Access Journals (Sweden)

    Luiz Claudio Pereira Ribeiro

    2013-09-01

    Full Text Available Intrathecal synthesis of human T-lymphotropic virus type 1 (HTLV-1 antibodies (Abs represents conclusive evidence of a specific immune response in the central nervous system of HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP patients. Western blotting (WB for HTLV Abs in serum is a confirmatory test for HTLV-1 infection. The aim of this study was to standardise the Western blot to demonstrate the intrathecal pattern of Abs against HTLV-1 proteins in HAM/TSP patients. Paired cerebrospinal fluid (CSF and serum samples were selected from 20 patients with definite HAM/TSP, 19 HTLV-1 seronegative patients and two HTLV-1 patients without definite HAM/TSP. The presence of reactive bands of greater intensity in the CSF compared to serum (or bands in only the CSF indicated the intrathecal synthesis of anti-HTLV-1 Abs. All definite HAM/TSP patients presented with an intrathecal synthesis of anti-HTLV-1 Abs; these Abs were not detected in the control patients. The most frequent intrathecal targets of anti-HTLV-1 Abs were GD21, rgp46-I and p24 and, to a lesser extent, p19, p26, p28, p32, p36, p53 gp21 and gp46. The intrathecal immune response against env (GD21 and rgp46-I and gag (p24 proteins represents the most important humoral pattern in HAM/TSP. This response may be used as a diagnostic marker, considering the frequent association of intrathecal anti-HTLV-1 Ab synthesis with HAM/TSP and the pathogenesis of this neurological disease.

  20. Saharan dust contributions to PM10 and TSP levels in Southern and Eastern Spain

    Science.gov (United States)

    Rodríguez, S.; Querol, X.; Alastuey, A.; Kallos, G.; Kakaliagou, O.

    The analysis of PM10 and TSP levels recorded in rural areas from Southern and Eastern Spain (1996-1999) shows that most of the PM10 and TSP peak events are simultaneously recorded at monitoring stations up to 1000 km apart. The study of the atmospheric dynamics by back-trajectory analysis and simulations with the SKIRON Forecast System show that these high PM10 and TSP events occur when high-dust Saharan air masses are transported over the Iberian Peninsula. In the January-June period, this dust transport is mainly caused by cyclonic activity over the West or South of Portugal, whereas in the summer period this is induced by anticyclonic activity over the East or Southeast Iberian Peninsula. Most of the Saharan intrusions which exert a major influence on the particulate levels occur from May to September (63%) and in January and October. In rural areas in Northeast Spain, where the PM10 annual mean is around 18 μg PM10 m -3, the Saharan dust accounts for 4-7 annual daily exceedances of the forthcoming PM10-EU limit value (50 μg PM10 m -3 daily mean). Higher PM10 background levels are recorded in Southern Spain (30 μg PM10 m -3 as annual mean for rural areas) and very similar values are recorded in industrial and urban areas. In rural areas in Southern Spain, the Saharan dust events accounts for 10-23 annual daily exceedances of the PM10 limit value, a high number when compared with the forthcoming EU standard, which states that the limit value cannot be exceeded more than 7 days per year. The proportion of Sahara-induced exceedances with respect to the total annual exceedances is discussed for rural, urban and industrial sites in Southern Spain.

  1. Radon exposure in selected underground touring routes in Poland

    International Nuclear Information System (INIS)

    Olszewski, J.; Chruscielewski, W.; Jankowski, J.

    2006-01-01

    The radioactive elements abounding in the natural environment cause that the whole human population is exposed to radiation. In Poland, mean gamma radiation dose power is 45.4 n Gy h -1 , while atmospheric radon concentration is 4.4 Bq m -3 [1]. In closed rooms, where radon tends to accumulate, the concentrations may be many times higher.Underground touring routes located in caves, mines, ancient cellars, vaults may accumulate radon at concentrations several thousand times exceeding its atmospheric levels. Studies on natural radioactivity in underground touring routes, with particular reference to caves, have continued worldwide since the 80's. Current register of underground touring routes in Poland comprises over 30 items, which include caves (e.g. Niedzwiedzia), mines (Wieliczka), cellars and underground stores (Opatow City vaults) and military objects (underground factories of Walim). The Nofer Institute of Occupational Medicine has for several years already continued determinations of periodical mean radon concentrations in four underground touring routes (starting date in parentheses): Niedzwiedzia Cave (1995); Kowary Drifts closed uranium mine (2001); closed uranium mine in Kletno (2004); Zloty Stok closed gold mine (2004); Osowka underground city in Gluszyca (2004).The results of our determinations of radon concentrations at five selected touring routes lead to the following conclusions. 1. The exposure in the Kowary Drifts touring route is at the level of 5% of the recommended maximum annual admissible limit of 20 mSv. 2. It is assessed that workers of the touring routes where exposures are estimated from the measured concentrations and the time spent underground may receive doses ranging from 0.01 to 5 mSv. (N.C.)

  2. Radon exposure in selected underground touring routes in Poland

    Energy Technology Data Exchange (ETDEWEB)

    Olszewski, J.; Chruscielewski, W.; Jankowski, J. [Nofer Institute of Occupational Medicine, Dept. of Radiation Protection, Lodz (Poland)

    2006-07-01

    The radioactive elements abounding in the natural environment cause that the whole human population is exposed to radiation. In Poland, mean gamma radiation dose power is 45.4 n Gy h{sup -1}, while atmospheric radon concentration is 4.4 Bq m{sup -3} [1]. In closed rooms, where radon tends to accumulate, the concentrations may be many times higher.Underground touring routes located in caves, mines, ancient cellars, vaults may accumulate radon at concentrations several thousand times exceeding its atmospheric levels. Studies on natural radioactivity in underground touring routes, with particular reference to caves, have continued worldwide since the 80's. Current register of underground touring routes in Poland comprises over 30 items, which include caves (e.g. Niedzwiedzia), mines (Wieliczka), cellars and underground stores (Opatow City vaults) and military objects (underground factories of Walim). The Nofer Institute of Occupational Medicine has for several years already continued determinations of periodical mean radon concentrations in four underground touring routes (starting date in parentheses): Niedzwiedzia Cave (1995); Kowary Drifts closed uranium mine (2001); closed uranium mine in Kletno (2004); Zloty Stok closed gold mine (2004); Osowka underground city in Gluszyca (2004).The results of our determinations of radon concentrations at five selected touring routes lead to the following conclusions. 1. The exposure in the Kowary Drifts touring route is at the level of 5% of the recommended maximum annual admissible limit of 20 mSv. 2. It is assessed that workers of the touring routes where exposures are estimated from the measured concentrations and the time spent underground may receive doses ranging from 0.01 to 5 mSv. (N.C.)

  3. Aseguramiento de la Calidad en el Proceso de Desarrollo de Software utilizando CMMI, TSP y PSP

    OpenAIRE

    Chavarría, Alex Espejo; Oré, Sussy Bayona; Pastor, Carlos

    2016-01-01

    En la actualidad las empresas que desarrollan software se han convertido en socios estratégicos de sus clientes a través de la generación de valor, mediante la entrega de productos que soportan sus diversos procesos de negocio. Sin embargo, aún existen problemas en los proyectos de desarrollo de software como la calidad. En este artículo se describe los resultados de la implementación de un modelo de aseguramiento de la calidad que integra CMMI (Capability Maturity Model Integration), TSP (Te...

  4. A performance evaluation of ACO and SA TSP in a supply chain network

    Science.gov (United States)

    Rao, T. Srinivas

    2017-07-01

    Supply Chain management and E commerce business solutions are one of the prominent areas of active research. In our paper we have modelled a supply chain model which aggregates all the manufacturers requirement and the products are supplied to all the manufacturer through a common vehicle routing algorithm. An appropriate tsp has been constructed for all the manufacturers which determines the shortest route thru which the aggregated material can be supplied in the shortest possible time. In this paper we have solved the shortest route through constructing a Simulated annealing algorithm and Ant colony algorithm and their performance is evaluated.

  5. Dorothy Jorgensen - Co-Op Tour Summary

    Science.gov (United States)

    Jorgensen, Dorothy

    2014-01-01

    NASA is a household name in this day and age, known commonly as America's government-run powerhouse of innovation and space exploration. It is a common dream for students to be a part of NASA's workforce, but I did not realize that it was my dream until I found that I could not imagine working anywhere else. From August to December, I had the privilege of a co-op tour with NASA at the Johnson Space Center. The National Aeronautics and Space Administration (NASA) first formed in the early hysteria of the Cold War, and in its early days it received enormous funding and political support. It was America's response to the Russian Sputnik, which was a not only a stark symbol of what was suddenly possible, but also of how far behind the United States had fallen in the race for technology. The political atmosphere in the world has since changed, but NASA's drive to push the boundaries of the impossible has not faded: NASA's primary mission has been exploration for the betterment of mankind, and it works towards that mission to this day. The specific NASA site that I worked in was by a coast near Houston, TX, at the Johnson Space Center (Figure 1). I was led on my first day of work to a building dedicated to Structural Engineering (Building 13), which was where I would be spending most of my time in the months to come. It was here that I had my desk and cubicle, and would later do the bulk of my computer modeling and theoretical planning. Later that day we traveled to the Vibrations and Acoustics Test Facility (Building 49), and here I was shown the parts we would use for our technical project and the locations we would work in. I worked in the Loads and Dynamics Branch of the Structural Engineering Division, in the Engineering Directorate.

  6. PEMANFAATAN TEKNOLOGI GOOGLE MAPS UNTUK PENYELESAIAN ONLINE TRAVELLING SALESMAN PROBLEM (TSP BERBASIS GEOGRAFIS DENGAN MENGGUNAKAN ALGORITMA HEURISTIK

    Directory of Open Access Journals (Sweden)

    Wahyudi Agustiono

    2010-07-01

    Full Text Available Travelling Salesman Problem (TSP adalah salah satu metode klasik dalam proses pemecahan masalah optimasi dan penemuan rute terpendek dari sebuah rute perjalanan yang melewati beberapa titik lokasi. Oleh karena kehandalan metode ini banyak sekali algoritma dan metode optimasi yang mencoba memecahkan TSP dalam banyak penelitian. Sebagin besar hasil dari rangkaian ujicoba tersebut berupa kombinasi teroptimal dari rangkaian perjalanan salesman yang umumnya digambarkan dalam sebuah graph. Namun belum banyak penelitian yang menerapkan TSP pada data spasial atau geografis seperti Google Maps yang dapat memberikan representasi nyata permasalahan TSP dalam menemukan rute perjalanan melewati titik-titik wilayah di muka bumi. Dibandingkan dengan representasi graph, Google Maps memiliki kemampuan tidak sekedar menampilkan rute perjalanan akan tetapi juga dapat menyajikan informasi yang lebih komprehensif, interaktif dan faktual. Penelitian ini bertujuan untuk menerapkan metode TSP pada layanan data spasial sehingga akan dihasilkan visualisasi secara riil dari alternatif rute perjalanan salesman. Sebagai basis dari data spasial, penelitian ini memanfaatkan Google Maps Mashup untuk mendapatkan informasi rute yang lebih aktual, interaktif, dan komprehensif.

  7. Chemical mass balance source apportionment of TSP in a lignite-burning area of Western Macedonia, Greece

    Science.gov (United States)

    Samara, Constantini

    Total suspended particle mass concentrations (TSP) were determined in the Kozani-Ptolemais-Florina basin (western Macedonia, Greece), an area with intensive lignite burning for power generation. The study was conducted over a 1-year period (November 2000-November 2001) at 10 receptor sites located at variable distances from the power plants. Ambient TSP samples were analyzed for 27 major, minor and trace elements. Particulate emissions were also collected from a variety of sources including fly ash, lignite dust, automobile traffic, domestic heating, and open-air burning of agricultural biomass and refuse, and analyzed for the same chemical components. Ambient and source chemical profiles were used for source identification and apportionment of TSP by employing a chemical mass balance (CMB) receptor model. Diesel burning in vehicular traffic and in the power plants for generator start up was found to be the major contributor to ambient TSP levels at all 10 sites. Other sources with significant contributions were domestic coal burning, vegetative burning (wood combustion and agricultural burns) and refuse open-air burning. Fly ash escaping the electrostatic precipitators of the power plants was a minor contributor to ambient TSP.

  8. Corrosion and solubility in a TSP-buffered chemical environment following a loss of coolant accident: Part 2 – Zinc

    International Nuclear Information System (INIS)

    Pease, David; LaBrier, Daniel; Ali, Amir; Blandford, Edward D.; Howe, Kerry J.

    2016-01-01

    Highlights: • Zinc release is limited to less than 1 mg/L in TSP-buffered solution under a variety of conditions (pH, temperature, zinc source). • Zinc release in high-temperature non-TSP-buffered environment is approximately 25 mg/L. • Long-term zinc release is controlled by passivation (without TSP) and zinc solubility (with TSP). • Precipitation and solubility of zinc phosphate limit the release of zinc. - Abstract: Bench experiments were conducted to investigate the effect of the presence of trisodium phosphate (TSP) on the corrosion and release of zinc from metallic zinc-bearing surfaces under conditions representative of the containment pool following a postulated loss of coolant accident (LOCA) at a nuclear power generating facility. The experiments showed that in non-buffered (acidic) environments, measurable quantities of zinc are released from zinc-bearing surfaces. Precipitation and solubility of phosphate-based corrosion products, such as zinc phosphate, limit the release of zinc from zinc-bearing surfaces. These experiments have found that under a variety of conditions, including variations of temperature, pH, and across different zinc-bearing surfaces, the release of zinc into solution is limited to <1 mg/L when phosphate is present. When phosphate is not present, zinc release is instead bounded by a markedly higher saturation limit which is a strong function of the solution temperature.

  9. Balancing emergency message dissemination and network lifetime in wireless body area network using ant colony optimization and Bayesian game formulation

    Directory of Open Access Journals (Sweden)

    R. Latha

    Full Text Available Nowadays, Wireless Body Area Network (WBAN is emerging very fast and so many new methods and algorithms are coming up for finding the optimal path for disseminating emergency messages. Ant Colony Optimization (ACO is one of the cultural algorithms for solving many hard problems such as Travelling Salesman Problem (TSP. ACO is a natural behaviour of ants, which work stochastically with the help of pheromone trails deposited in the shortest route to find their food. This optimization procedure involves adapting, positive feedback and inherent parallelism. Each ant will deposit certain amount of pheromone in the tour construction it makes searching for food. This type of communication is known as stigmetric communication. In addition, if a dense WBAN environment prevails, such as hospital, i.e. in the environment of overlapping WBAN, game formulation was introduced for analyzing the mixed strategy behaviour of WBAN. In this paper, the ant colony optimization approach to the travelling salesman problem was applied to the WBAN to determine the shortest route for sending emergency message to the doctor via sensor nodes; and also a static Bayesian game formulation with mixed strategy was analysed to enhance the network lifetime. Whenever the patient needs any critical care or any other medical issue arises, emergency messages will be created by the WBAN and sent to the doctor's destination. All the modes of communication were realized in a simulation environment using OMNet++. The authors investigated a balanced model of emergency message dissemination and network lifetime in WBAN using ACO and Bayesian game formulation. Keywords: Wireless body area network, Ant colony optimization, Bayesian game model, Sensor network, Message latency, Network lifetime

  10. Challenges Affecting the Quality Service of the Tour Guide in Egypt

    Directory of Open Access Journals (Sweden)

    Heba Magdy

    2016-07-01

    Full Text Available The research spots the light on the challenges that face the Egyptian tour guide and could affect on his service quality. Several studies were previously done on these challenges in other countries; however, this study is considered the first to be done in Egypt. The researcher depended on interviews with members of the Egyptian tour-guiding Syndicate, travel agencies, and numbers of Tour-guides. Through these interviews certain challenges are detected: the poor payment, the role conflict between the tour leader and the tour-guide, the foreign labour, feeling not appreciated from the government, renewing the licence, creation of other tour-guiding jobs.

  11. The job that no one wants to do? Museum educators’ articulations about guided tours

    Directory of Open Access Journals (Sweden)

    Cecilia Rodehn

    2017-03-01

    Full Text Available The aim of this paper is to investigate museum educators’ articulations of their performance during guided tours. The paper investigates preparations for a guided tour, considerations related to doing guided tours and the events after the guided tour. The text focus especially on preparation and the aftermath as this is not normally discussed in research on museum education. The paper is based on participant observation of guided tours, filming of guided tours and qualitative semi-structured interviews. The material is analysed using performance theories and theories on materiality. The paper seeks to unearth knowledge imbued in the museum educators’ performance and reveal what can be known from guiding bodies.

  12. Model Strategi Prospektif Kinerja Manajemen di Perusahaan Tour & Travel

    Directory of Open Access Journals (Sweden)

    Rudy Aryanto

    2010-11-01

    Full Text Available This study aimed to build a prospective management model of sustainable tour packages in PT. Golden Rama Express. Given the complexity and the many interrelated factors in the performance management packagetours, it is necessary to approach a holistic system. First, the method used in developing the performance management model is a sustainable package tour and, second, using prospective analysis. Determination of the attributes that reflect the sustainability performance of the tour package is based on field studies. Based on the four dimensions of sustainability, namely the dimensions before the trip, during trip, etc., and the tour leader aredetermined as much as 23 attributes. Attributes in four dimensions for each package tour Junglelicious Africa, Asia Splendid, Adventurous Australia and New Zealand, Europe Romantical and Marvelous the U.S. and Canada. After obtained the level of sustainability index values of each dimension that can be categorized into the not sustainable until very sustainable values of the index, combination of these factors forms the basis of development models.. Based on the scenario that was built and in order to achieve the ideal scenario is the recommended scenario is the optimistic scenario.

  13. Reassessing Occupational Licensing Of Tour Guides (Opinion Piece

    Directory of Open Access Journals (Sweden)

    Amir SHANI

    2017-06-01

    Full Text Available It is conventionally held that to protect tourists from incompetent and/or unscrupulous tour guides, governments should require guides to be licensed in order to legally practice their profession. Despite the implementation of such regulatory statutes in many countries, it is argued in this opinion paper that the severe drawbacks of licensing demands should be re-evaluated by both policy-makers and tourism scholars. The licensing of guides is not only an ineffective means of quality assurance, with negative consequences for many of those involved, but it also undermines the ethical foundations of a free society. Furthermore, licensing is an archaic practice for ensuring standardization among the members of a profession in a way that is no longer suitable for addressing the challenges of the tourism industry in the 21st century, in which a wide variety of specialized and innovative guided tours are offered to tourists. Although this commentary presents a firm stand against the compulsory licensing of tour guides, it should be seen as an invitation for open discussion among tourism researchers regarding the necessity of licensing tour guides in particular, and of government tourism regulation in general. Moreover, further research is needed to clarify key points on the issue of the professional licensing of tour guides.

  14. STRATEGI PEMASARAN PAKET WISATA FULL DAY DI PT. TOUR EAST INDONESIA

    Directory of Open Access Journals (Sweden)

    Putu Geni Jaya Ksamawan

    2017-01-01

    Full Text Available he development of increasing tourist arrivals to Bali led to the development of business and tourism in the world of business, one business trip in Bali. PT. Tour East Tours and Travel is the one of the travel agents in Bali in this to win the competition with other companies, the need for proper marketing strategy and correct. This study aims to determine the marketing strategy Full Day tour packages PT. Tour East Indonesia and what strategies can be implemented in the PT. Tour East Tours and Travel to boost sales of tour packages to tourists as well as winning the competition with other companies. In this study using Qualitative descriptive data analysis techniques combined with a SWOT analysis to figure out what the right strategy is used to market tour packages Full Day of PT. Tour East Indonesia. Based on the SWOT matrix analysis obtained a marketing strategy that can be applied to PT. Tour East Tours and Travel is a strategy creation and development of tourism products, increased promotion strategies, human resource development strategy, market segmentation strategy development, and strategies for improving the quality of products and services. From the results of this study can be given advice to the PT. Tour East Tours and Travel is improving service process management and define market segments and maintain the image of the internal and external environment, while maintaining a cooperative relationship, and held training to staff meetings.

  15. Corrosion and solubility in a TSP-buffered chemical environment following a loss of coolant accident: Part 1 – Aluminum

    Energy Technology Data Exchange (ETDEWEB)

    Howe, Kerry J., E-mail: howe@unm.edu [University of New Mexico, 210 University Blvd., Albuquerque, NM 87131 (United States); Mitchell, Lana, E-mail: lmitchell@alionscience.com [University of New Mexico, 210 University Blvd., Albuquerque, NM 87131 (United States); Kim, Seung-Jun, E-mail: skim@lanl.gov [University of New Mexico, 210 University Blvd., Albuquerque, NM 87131 (United States); Blandford, Edward D., E-mail: edb@unm.edu [University of New Mexico, 210 University Blvd., Albuquerque, NM 87131 (United States); Kee, Ernest J., E-mail: erniekee@gmail.com [South Texas Project Nuclear Operating Company, P.O. Box 270, Wadsworth, TX 77483 (United States)

    2015-10-15

    Highlights: • Trisodium phosphate (TSP) causes aluminum corrosion to cease after 24 h of exposure. • Chloride, iron, and copper have a minimal effect on the rate of aluminum corrosion when TSP is present. • Zinc can reduce the rate of aluminum corrosion when TSP is present. • Aluminum occasionally precipitates at concentrations lower than the calculated solubility for Al(OH){sub 3}. • Corrosion and solubility equations can be used to calculate the solids generated during a LOCA. - Abstract: Bench experiments were conducted to investigate the effect of the presence of trisodium phosphate (TSP) on the corrosion and release of aluminum from metallic aluminum surfaces under conditions representative of the containment pool following a postulated loss of coolant accident at a nuclear power generating facility. The experiments showed that TSP is capable of passivating the aluminum surface and preventing continued corrosion after about 24 h at the conditions tested. A correlation that describes the rate of corrosion including the passivation effect was developed from the bench experiments and validated with a separate set of experiments from a different test system. The saturation concentration of aluminum was shown to be well described by the solubility of amorphous aluminum hydroxide for the majority of cases, but instances have been observed when aluminum precipitates at concentrations lower than the calculated aluminum hydroxide solubility. Based on the experimental data and previous literature, an equation was developed to calculate the saturation concentration of aluminum as a function of pH and temperature under conditions representative of a loss of coolant accident (LOCA) in a TSP-buffered pressurized water reactor (PWR) containment. The corrosion equation and precipitation equation can be used in concert with each other to calculate the quantity of solids that would form as a function of time during a LOCA if the temperature and pH profiles were known.

  16. Corrosion and solubility in a TSP-buffered chemical environment following a loss of coolant accident: Part 1 – Aluminum

    International Nuclear Information System (INIS)

    Howe, Kerry J.; Mitchell, Lana; Kim, Seung-Jun; Blandford, Edward D.; Kee, Ernest J.

    2015-01-01

    Highlights: • Trisodium phosphate (TSP) causes aluminum corrosion to cease after 24 h of exposure. • Chloride, iron, and copper have a minimal effect on the rate of aluminum corrosion when TSP is present. • Zinc can reduce the rate of aluminum corrosion when TSP is present. • Aluminum occasionally precipitates at concentrations lower than the calculated solubility for Al(OH) 3 . • Corrosion and solubility equations can be used to calculate the solids generated during a LOCA. - Abstract: Bench experiments were conducted to investigate the effect of the presence of trisodium phosphate (TSP) on the corrosion and release of aluminum from metallic aluminum surfaces under conditions representative of the containment pool following a postulated loss of coolant accident at a nuclear power generating facility. The experiments showed that TSP is capable of passivating the aluminum surface and preventing continued corrosion after about 24 h at the conditions tested. A correlation that describes the rate of corrosion including the passivation effect was developed from the bench experiments and validated with a separate set of experiments from a different test system. The saturation concentration of aluminum was shown to be well described by the solubility of amorphous aluminum hydroxide for the majority of cases, but instances have been observed when aluminum precipitates at concentrations lower than the calculated aluminum hydroxide solubility. Based on the experimental data and previous literature, an equation was developed to calculate the saturation concentration of aluminum as a function of pH and temperature under conditions representative of a loss of coolant accident (LOCA) in a TSP-buffered pressurized water reactor (PWR) containment. The corrosion equation and precipitation equation can be used in concert with each other to calculate the quantity of solids that would form as a function of time during a LOCA if the temperature and pH profiles were known

  17. WE-C-TOUR-T-01: Microdosimeters for Therapy

    International Nuclear Information System (INIS)

    Das, I.

    2016-01-01

    Tour Leader: Indra Das, NYU Langone Medical Center, New York, NY Tour Guides: Hsui Ai, Indiana University School of Medicine, Indianapolis, IN Paulina Galvis, NYU Langone Medical Center, New York, NY Olga Volotoskova, NYU Langone Medical Center, New York, NY Participating Vendors: IBA PTW – New York RTI Electronics, Inc. Standard Imaging, Inc. Sun Nuclear Corporation Small fields are increasing used in specialized radiation treatments such as Gammaknife, Cyberknife, Tomotherapy, IMRT, VMAT, SRS and SBRT. Due to small field size electron transport creates lateral electronic disequilibrium and thus dosimetry could be very difficult. Microdetectors are used for small field dosimetry which will be discussed in preface of this tour as below: Understanding small field e.g. meaning and definition of small field IAEA definition and approach Characteristics of microdetectors in terms of perturbation, recombination, correction Suitability of microdetectors in small field dosimetry

  18. Production of the next-generation library virtual tour

    Science.gov (United States)

    Duncan, James M.; Roth, Linda K.

    2001-01-01

    While many libraries offer overviews of their services through their Websites, only a small number of health sciences libraries provide Web-based virtual tours. These tours typically feature photographs of major service areas along with textual descriptions. This article describes the process for planning, producing, and implementing a next-generation virtual tour in which a variety of media elements are integrated: photographic images, 360-degree “virtual reality” views, textual descriptions, and contextual floor plans. Hardware and software tools used in the project are detailed, along with a production timeline and budget, tips for streamlining the process, and techniques for improving production. This paper is intended as a starting guide for other libraries considering an investment in such a project. PMID:11837254

  19. A Website: a Way to Promote the Products and the Services of Salim International Tours and Travel

    OpenAIRE

    Merari, Clarrisa; Ibrahim, Jusuf I

    2015-01-01

    Salim Tours and Travels offers various services such as reserving flight tickets (domestic and International), reserving hotel rooms, assisting clients to apply for passports or visas and providing International or domestic tours. Salim Tours and Travels is located on Panglima Sudirman 72-1, Surabaya, which is at the center of Surabaya. Salim Tours and Travel Agency was established on 2nd February, 2002 in Surabaya. Because of Tour and Travel have a good prospect in the future, Salim Tours ne...

  20. Imaging spinal cord atrophy in progressive myelopathies: HTLV-I-associated neurological disease (HAM/TSP) and multiple sclerosis (MS).

    Science.gov (United States)

    Azodi, Shila; Nair, Govind; Enose-Akahata, Yoshimi; Charlip, Emily; Vellucci, Ashley; Cortese, Irene; Dwyer, Jenifer; Billioux, B Jeanne; Thomas, Chevaz; Ohayon, Joan; Reich, Daniel S; Jacobson, Steven

    2017-11-01

    Previous work measures spinal cord thinning in chronic progressive myelopathies, including human T-lymphotropic virus 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and multiple sclerosis (MS). Quantitative measurements of spinal cord atrophy are important in fully characterizing these and other spinal cord diseases. We aimed to investigate patterns of spinal cord atrophy and correlations with clinical markers. Spinal cord cross-sectional area was measured in individuals (24 healthy controls [HCs], 17 asymptomatic carriers of HTLV-1 (AC), 47 HAM/TSP, 74 relapsing-remitting MS [RRMS], 17 secondary progressive MS [SPMS], and 40 primary progressive MS [PPMS]) from C1 to T10. Clinical disability scores, viral markers, and immunological parameters were obtained for patients and correlated with representative spinal cord cross-sectional area regions at the C2 to C3, C4 to C5, and T4 to T9 levels. In 2 HAM/TSP patients, spinal cord cross-sectional area was measured over 3 years. All spinal cord regions are thinner in HAM/TSP (56 mm 2 [standard deviation, 10], 59 [10], 23 [5]) than in HC (76 [7], 83 [8], 38 [4]) and AC (71 [7], 78 [9], 36 [7]). SPMS (62 [9], 66 [9], 32 [6]) and PPMS (65 [11], 68 [10], 35 [7]) have thinner cervical cords than HC and RRMS (73 [9], 77 [10], 37 [6]). Clinical disability scores (Expanded Disability Status Scale [p = 0.009] and Instituto de Pesquisas de Cananeia [p = 0.03]) and CD8 + T-cell frequency (p = 0.04) correlate with T4 to T9 spinal cord cross-sectional area in HAM/TSP. Higher cerebrospinal fluid HTLV-1 proviral load (p = 0.01) was associated with thinner spinal cord cross-sectional area. Both HAM/TSP patients followed longitudinally showed thoracic thinning followed by cervical thinning. Group average spinal cord cross-sectional area in HAM/TSP and progressive MS show spinal cord atrophy. We further hypothesize in HAM/TSP that is possible that neuroglial loss from a thoracic inflammatory

  1. Exposure of tour guides to Radon at the Cango caves

    International Nuclear Information System (INIS)

    Pule, O.J.; Lindsay, R.

    2008-01-01

    Full text: A study was commissioned by the National Nuclear Regulator of South Africa to investigate the radon levels in the Cango caves and the associated radiological exposure to tour guides. The Cango caves are about 1.3 km in length and are visited by about 300000 tourists per annum due to their natural beauty. This study followed an earlier investigation by the Department of Health which indicated levels in excess of 1000 Bqm -3 which could lead to excess exposure of the cave tour guides. Radon in the various cave chambers and radon exposure of tour guides was measured using RAD-7 continuous radon monitor, electrets ion chambers and personnel monitoring electrets respectively. The measurements in the cave were done during summer and winter seasons to determine any variations between the seasons. The occupancy time for individual guides and equilibrium factor were also investigated. The radon concentration in the cave range from 1000 Bqm -3 to more than 2000 Bqm -3 with equilibrium factor of approximately 0.4, and the variation between winter and summer measurements are insignificant. The radon exposure levels to tour guides differ due to various time periods they spent in the caves. The average dose to tour guides due to radon is 7 mSv -a and the highest exposure is about 10 mSv -a . The exposure to tourists is found to be insignificant due to time they spent in the cave. The regulatory authority is currently investigating what action is necessary to protect the tour guides. (author)

  2. iPod tours: a new approach to induction

    OpenAIRE

    Mawson, M.

    2007-01-01

    This article is based on a presentation given at a conference organized by cpd 25 in April 2007; “The Library in the Interactive Environment: Practical use of technology to improve the student experience”. It describes the development and creation of an iPod induction tour for the Main Library at Sheffield University, with input from students. It also discusses the use and evaluation of the tour, and concludes by describing how the Library is using the experience to consider other technologie...

  3. Development of improved ambient computation methods in support of the National Parks Air Tour Management Act

    Science.gov (United States)

    2008-09-01

    Approximately 85 National Park units with commercial air tours will need Air Tour : Management Plans (ATMPs). The objective of an ATMP is to prevent or mitigate : significant adverse impacts to National Park resources. Noise impacts must be : charact...

  4. Kaloko-Honokohau National Historical Park Air Tour Management Plan planning and NEPA scoping document

    Science.gov (United States)

    2004-03-03

    The Federal Aviation Administration (FAA), in cooperation with the National Park Service (NPS), has initiated the development of an Air Tour Management Plan (ATMP) for Kaloko-Honokohau Historic Park pursuant to the National Parks Air Tour Management ...

  5. Kalaupapa National Historic Park Air Tour Management Plan planning and NEPA scoping study

    Science.gov (United States)

    2005-03-03

    The Federal Aviation Administration (FAA), in cooperation with the National Park Service (NPS), has initiated the development of an Air Tour Management Plan (ATMP) for Kalaupapa Historic Park pursuant to the National Parks Air Tour Management Act of ...

  6. Convex hull and tour crossings in the Euclidean traveling salesperson problem : implications for human performance studies

    NARCIS (Netherlands)

    Rooij, van I.; Stege, U.; Schactman, A.

    2003-01-01

    Recently there has been growing interest among psychologists in human performance on the Euclidean traveling salesperson problem (E-TSP). A debate has been initiated on what strategy people use in solving visually presented E-TSP instances. The most prominent hypothesis is the convex-hull

  7. 41 CFR 102-117.50 - What are the advantages and disadvantages of contracting directly with a TSP under the FAR?

    Science.gov (United States)

    2010-07-01

    ... and disadvantages of contracting directly with a TSP under the FAR? 102-117.50 Section 102-117.50... Related Services § 102-117.50 What are the advantages and disadvantages of contracting directly with a TSP... office is able to handle the requirement. (b) The FAR may be a disadvantage when you: (1) Cannot prepare...

  8. Enhancing the Entertainment Experience of Blind and Low-Vision Theatregoers through Touch Tours

    Science.gov (United States)

    Udo, J. P.; Fels, D. I.

    2010-01-01

    In this paper we demonstrate how universal design theory and the research available on museum-based touch tours can be used to develop a touch tour for blind and low-vision theatregoers. We discuss these theoretical and practical approaches with reference to data collected and experience gained from the creation and execution of a touch tour for…

  9. 41 CFR 302-3.209 - What is overseas tour renewal travel?

    Science.gov (United States)

    2010-07-01

    ... renewal travel? 302-3.209 Section 302-3.209 Public Contracts and Property Management Federal Travel... of Transfers Overseas Tour Renewal Agreement § 302-3.209 What is overseas tour renewal travel? Overseas tour renewal travel refers to travel of you and your immediate family returning to your home in...

  10. 76 FR 26948 - Small Business Jobs Act Tour: Selected Provisions Having an Effect on Government Contracting

    Science.gov (United States)

    2011-05-10

    ...] Small Business Jobs Act Tour: Selected Provisions Having an Effect on Government Contracting AGENCY: U.S... INFORMATION CONTACT: Richard L. Miller, Small Business Job's Act Tour-Office of Government Contracting and..., concerning the Small Business Act Tour: Selected Provisions Having an Effect on Government that announced a...

  11. Ariadne: a Java-based guided tour system for the World Wide Web

    DEFF Research Database (Denmark)

    Jühne, Jesper; Jensen, Anders T.; Grønbæk, Kaj

    1998-01-01

    This paper presents a Guided tour system for the WWW, called Ariadne, which implements the ideas of trails and guided tours, originating from the hypertext field. Ariadne appears as a Java applet to the user and it stores guided tours in a database format separated from the WWW documents included...

  12. Fermilab Ed Office - High School Tour Request Form

    Science.gov (United States)

    will not work. Programs | Science Adventures | Calendar | Registration | About | Contact | FAQ capacity for physical science tours in April 2018. We will try to accommodate all requests but there is -St Charles CUSD 303-St Charles Kendall-Lisbon CCSD 90-Newark Kendall-Newark CCSD 66-Newark Kendall

  13. Aendringer i blodprofiler under Tour de France 2007

    DEFF Research Database (Denmark)

    Mørkeberg, Jakob; Belhage, Bo; Damsgaard, Rasmus

    2008-01-01

    sports federations. MATERIALS AND METHODS: During the Tour de France 2007, 7 riders were randomly tested on 3 different occasions; the day before the prologue, and 12 and 19 days after the prologue. Blood was drawn into 3 mL EDTA covered tubes and kept at 4 degrees Celsius. They were analyzed within 24...

  14. The Use of Theatre Tours in Road Safety Education.

    Science.gov (United States)

    Powney, Janet; And Others

    The Scottish Road Safety Campaign and the Road Safety Council of Wales have made a large investment in theater tours as a method of providing road safety education. This study aimed to evaluate the effectiveness of a road safety message delivered by a theater group, Road Safety Officers (RSOs), or, teachers for pupils in upper secondary classes.…

  15. Fostering Student Engagement through a Multi-Day Industry Tour

    Science.gov (United States)

    Taylor, Lorraine L.; Hartman, Cindy L.; Baldwin, Elizabeth D.

    2015-01-01

    Student engagement may be enhanced by providing educationally purposeful activities outside of the classroom. This study considers the influence of a multi-day industry tour on student engagement for undergraduates majoring in Parks, Recreation and Tourism Management. Data were collected from students' reflections in journal entries focused on an…

  16. Touring between war and peace Imagining the 'transcontinental motorway', 19301950

    NARCIS (Netherlands)

    Badenoch, Alexander

    2007-01-01

    In 1930 the Alliance internationale de tourisme, a confederation of national cycle and motor touring clubs, set out plans for a motor road from London to Istanbul. This article explores the reasons for the road plan's relative success as a transnational project in the tense inter-war years by

  17. Getting Back to Basics: A Student Library Orientation Tour

    Science.gov (United States)

    Sciammarella, Susan; Fernandes, Maria Isabel

    2007-01-01

    In developing a Library Orientation Tour, it is important to be perceptive about the needs of a college population. At Queensborough Community College the student population is a mix of traditional and non-traditional students from diversified backgrounds. The initial contact with the Library, and its resources, may be overwhelming for students…

  18. Visitor Learning on Guided Tours: An Activity Theory Approach

    Science.gov (United States)

    Robinson, Lily Beatrice

    2016-01-01

    Guided tours, field trips, and other non-formal learning experiences occur in a variety of settings such as museums, parks, civic buildings, and architectural landmarks for the purpose of educating the public. This study yielded four main findings. (1) Program educational goals were visitor awareness, positive affective experience, and advocacy.…

  19. Text Version of the Indoor Air Quality House Tour

    Science.gov (United States)

    Get a quick glimpse of some of the most important ways to protect the air in your home by touring the Indoor Air Quality (IAQ) House. Room-by-room, you'll learn about the key pollutants and how to address them.

  20. 14 CFR 136.39 - Air tour management plans (ATMP).

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Air tour management plans (ATMP). 136.39... management plans (ATMP). (a) Establishment. The Administrator, in cooperation with the Director, shall... of decision. (d) Procedure. In establishing an ATMP for a national park or tribal lands, the...

  1. Virtual Tour Environment of Cuba's National School of Art

    Science.gov (United States)

    Napolitano, R. K.; Douglas, I. P.; Garlock, M. E.; Glisic, B.

    2017-08-01

    Innovative technologies have enabled new opportunities for collecting, analyzing, and sharing information about cultural heritage sites. Through a combination of two of these technologies, spherical imaging and virtual tour environment, we preliminarily documented one of Cuba's National Schools of Art, the National Ballet School.The Ballet School is one of the five National Art Schools built in Havana, Cuba after the revolution. Due to changes in the political climate, construction was halted on the schools before completion. The Ballet School in particular was partially completed but never used for the intended purpose. Over the years, the surrounding vegetation and environment have started to overtake the buildings; damages such as missing bricks, corroded rebar, and broken tie bars can be seen. We created a virtual tour through the Ballet School which highlights key satellite classrooms and the main domed performance spaces. Scenes of the virtual tour were captured utilizing the Ricoh Theta S spherical imaging camera and processed with Kolor Panotour virtual environment software. Different forms of data can be included in this environment in order to provide a user with pertinent information. Image galleries, hyperlinks to websites, videos, PDFs, and links to databases can be embedded within the scene and interacted with by a user. By including this information within the virtual tour, a user can better understand how the site was constructed as well as the existing types of damage. The results of this work are recommendations for how a site can be preliminarily documented and information can be initially organized and shared.

  2. TSP, PM10, and PM2.5 emissions from a beef cattle feedlot using the flux-gradient technique

    Science.gov (United States)

    Emissions data on air pollutants from large open-lot beef cattle feedlots are limited. This research was conducted to determine emissions of total suspended particulates (TSP) and particulate matter (PM10 and PM2.5) from a commercial beef cattle feedlot in Kansas (USA). Vertical particulate concentr...

  3. Analysis of the Effectiveness of the Retire Tool When Deciding Between High 36 Retirement and Blended TSP Retirement

    Science.gov (United States)

    2016-12-01

    22202-4302, and to the Office of Management and Budget , Paperwork Reduction Project (0704-0188) Washington DC 20503. 1. AGENCY USE ONLY (Leave...VALUE OF THE TSP ...........16 D. ELEMENTS OF RETIRE TOOL ANALYSIS .....................................18 1. Cash Flow Analysis...23 3. Cash Flow Comparison ...............................................................24 4. Volatility Analysis

  4. 41 CFR 102-118.45 - How does a transportation service provider (TSP) bill my agency for transportation and...

    Science.gov (United States)

    2010-07-01

    ... (b) Billing method (1)(i) Government issued agency charge card, (1) Bill from charge card company (may be electronic). (ii) Centrally billed travel account citation. (2)(i) Purchase order, (2) Bill from TSP (may be electronic). (ii) Bill of lading, (iii) Government Bill of Lading, (iv) Government...

  5. Seasonal variations of total suspended particles (TSP) and heavy metals under tropical conditions in Rio de Janeiro, Brazil

    International Nuclear Information System (INIS)

    Pfeiffer, W.C.; Trindade, H.A.; Costa-Ribeiro, C.; Londres, H.; Oliveira, A.E.

    The total suspended particle (TSP) and heavy metal concentrations are studied in Rio de Janeiro, Brazil from 1974 until 1981. The principal aims are to determine how these things vary in two different areas and how meteorological parameters responsible for the transport and dilution of atmospheric pollutants affect these areas. (M.A.C.) [pt

  6. Optimized Extreme Learning Machine for Power System Transient Stability Prediction Using Synchrophasors

    Directory of Open Access Journals (Sweden)

    Yanjun Zhang

    2015-01-01

    Full Text Available A new optimized extreme learning machine- (ELM- based method for power system transient stability prediction (TSP using synchrophasors is presented in this paper. First, the input features symbolizing the transient stability of power systems are extracted from synchronized measurements. Then, an ELM classifier is employed to build the TSP model. And finally, the optimal parameters of the model are optimized by using the improved particle swarm optimization (IPSO algorithm. The novelty of the proposal is in the fact that it improves the prediction performance of the ELM-based TSP model by using IPSO to optimize the parameters of the model with synchrophasors. And finally, based on the test results on both IEEE 39-bus system and a large-scale real power system, the correctness and validity of the presented approach are verified.

  7. The Expanded Invasive Weed Optimization Metaheuristic for Solving Continuous and Discrete Optimization Problems

    Directory of Open Access Journals (Sweden)

    Henryk Josiński

    2014-01-01

    Full Text Available This paper introduces an expanded version of the Invasive Weed Optimization algorithm (exIWO distinguished by the hybrid strategy of the search space exploration proposed by the authors. The algorithm is evaluated by solving three well-known optimization problems: minimization of numerical functions, feature selection, and the Mona Lisa TSP Challenge as one of the instances of the traveling salesman problem. The achieved results are compared with analogous outcomes produced by other optimization methods reported in the literature.

  8. LAFD: TA-15 DARHT Firefighter Facility Familiarization Tour, OJT 53044, Revision 0.2

    Energy Technology Data Exchange (ETDEWEB)

    Rutherford, Victor Stephen [Los Alamos National Laboratory; Priestley, Terry B. [Los Alamos National Laboratory; Maestas, Marvin Manuel [Los Alamos National Laboratory

    2016-03-17

    The Los Alamos National Laboratory (LANL or the Lab) will conduct familiarization tours for the Los Alamos County Fire Department (LAFD) at the Dual-Axis Radiographic Hydrodynamic Test (DARHT) Facility, TA-15-0312. The purpose of these tours is to orient LAFD firefighters to the DARHT facility layout and hazards. This document provides information and figures to supplement the familiarization tours. The document will be distributed to the trainees at the time of the familiarization tour. A checklist (Attachment A) has also been developed to ensure that all required information is consistently presented to LAFD personnel during the familiarization tours.

  9. Applying Data Clustering Feature to Speed Up Ant Colony Optimization

    Directory of Open Access Journals (Sweden)

    Chao-Yang Pang

    2014-01-01

    Full Text Available Ant colony optimization (ACO is often used to solve optimization problems, such as traveling salesman problem (TSP. When it is applied to TSP, its runtime is proportional to the squared size of problem N so as to look less efficient. The following statistical feature is observed during the authors’ long-term gene data analysis using ACO: when the data size N becomes big, local clustering appears frequently. That is, some data cluster tightly in a small area and form a class, and the correlation between different classes is weak. And this feature makes the idea of divide and rule feasible for the estimate of solution of TSP. In this paper an improved ACO algorithm is presented, which firstly divided all data into local clusters and calculated small TSP routes and then assembled a big TSP route with them. Simulation shows that the presented method improves the running speed of ACO by 200 factors under the condition that data set holds feature of local clustering.

  10. 41 CFR 302-3.216 - When must I begin my first tour renewal travel from Alaska or Hawaii?

    Science.gov (United States)

    2010-07-01

    ... first tour renewal travel from Alaska or Hawaii? 302-3.216 Section 302-3.216 Public Contracts and... must I begin my first tour renewal travel from Alaska or Hawaii? You must begin your first tour renewal travel within 5 years of your first consecutive tours in either Alaska or Hawaii. ...

  11. Solution Structure, Membrane Interactions, and Protein Binding Partners of the Tetraspanin Sm-TSP-2, a Vaccine Antigen from the Human Blood Fluke Schistosoma mansoni*

    Science.gov (United States)

    Jia, Xinying; Schulte, Leigh; Loukas, Alex; Pickering, Darren; Pearson, Mark; Mobli, Mehdi; Jones, Alun; Rosengren, Karl J.; Daly, Norelle L.; Gobert, Geoffrey N.; Jones, Malcolm K.; Craik, David J.; Mulvenna, Jason

    2014-01-01

    The tetraspanins (TSPs) are a family of integral membrane proteins that are ubiquitously expressed at the surface of eukaryotic cells. TSPs mediate a range of processes at the surface of the plasma membrane by providing a scaffold for the assembly of protein complexes known as tetraspanin-enriched microdomains (TEMs). We report here the structure of the surface-exposed EC2 domain from Sm-TSP-2, a TSP from Schistosoma mansoni and one of the better prospects for the development of a vaccine against schistosomiasis. This is the first solution structure of this domain, and our investigations of its interactions with lipid micelles provide a general model for interactions between TSPs, membranes, and other proteins. Using chemical cross-linking, eight potential protein constituents of Sm-TSP-2-mediated TEMs were also identified. These include proteins important for membrane maintenance and repair, providing further evidence for the functional role of Sm-TSP-2- and Sm-TSP-2-mediated TEMs. The identification of calpain, Sm29, and fructose-bisphosphate aldolase, themselves potential vaccine antigens, suggests that the Sm-TSP-2-mediated TEMs could be disrupted via multiple targets. The identification of further Sm-TSP-2-mediated TEM proteins increases the available candidates for multiplex vaccines and/or novel drugs targeting TEMs in the schistosome tegument. PMID:24429291

  12. Solution structure, membrane interactions, and protein binding partners of the tetraspanin Sm-TSP-2, a vaccine antigen from the human blood fluke Schistosoma mansoni.

    Science.gov (United States)

    Jia, Xinying; Schulte, Leigh; Loukas, Alex; Pickering, Darren; Pearson, Mark; Mobli, Mehdi; Jones, Alun; Rosengren, Karl J; Daly, Norelle L; Gobert, Geoffrey N; Jones, Malcolm K; Craik, David J; Mulvenna, Jason

    2014-03-07

    The tetraspanins (TSPs) are a family of integral membrane proteins that are ubiquitously expressed at the surface of eukaryotic cells. TSPs mediate a range of processes at the surface of the plasma membrane by providing a scaffold for the assembly of protein complexes known as tetraspanin-enriched microdomains (TEMs). We report here the structure of the surface-exposed EC2 domain from Sm-TSP-2, a TSP from Schistosoma mansoni and one of the better prospects for the development of a vaccine against schistosomiasis. This is the first solution structure of this domain, and our investigations of its interactions with lipid micelles provide a general model for interactions between TSPs, membranes, and other proteins. Using chemical cross-linking, eight potential protein constituents of Sm-TSP-2-mediated TEMs were also identified. These include proteins important for membrane maintenance and repair, providing further evidence for the functional role of Sm-TSP-2- and Sm-TSP-2-mediated TEMs. The identification of calpain, Sm29, and fructose-bisphosphate aldolase, themselves potential vaccine antigens, suggests that the Sm-TSP-2-mediated TEMs could be disrupted via multiple targets. The identification of further Sm-TSP-2-mediated TEM proteins increases the available candidates for multiplex vaccines and/or novel drugs targeting TEMs in the schistosome tegument.

  13. Espacio literario relevante sobre el problema del vendedor viajero (TSP: contenido, clasificación, métodos y campos de inspiración Relevant literary space on travelling salesman problem (TSP: contents, classification, methods and fields of inspiration

    Directory of Open Access Journals (Sweden)

    Jorge Ivan Pérez Rave

    2013-01-01

    Full Text Available Se describe y se analiza un espacio literario relevante sobre el Problema del Vendedor Viajero (TSP en términos de contenido, clases de TSP, métodos y campos de inspiración. Los datos empleados provinieron de los trabajos más citados en Scopus sobre el TSP, tanto a través de la historia como en el período 2006-2010. Se encontró que el TSP prevalece en las investigaciones, con enfoques tanto en el problema original como en sus variantes, entre las cuales se identificaron el TSP Múltiple y el TSP Probabilístico. Entre los principales campos de inspiración para resolver el TSP están la evolución biológica y su base genético-molecular, el comportamiento de hormigas reales, la termodinámica, las estrategias sistemáticas para combinar reglas de decisión y la búsqueda de vecindades. Hoy día se tiende a desarrollar métodos híbridos, especialmente integrando enfoques globales con búsquedas locales, y se identifica la necesidad de introducir nuevos campos de inspiración.This paper describes and analyzes, in terms of content, the types of TSP, methods and fields of inspiration - the most relevant "literary space" on TSP. It is built based on the top most cited on the TSP history and the Top 10 cited from 2006 to 2010. The study of TSP still prevails in Research, focusing on the original problem and its variants: Multiple TSP (m-TSP and Probabilistic TSP (PTSP. Evidence shows that there has been progress in the development of TSP solving methods, highlighted by various inspiration fields: biological evolution, behavior of real ants, thermodynamics, systematic strategies for combining decision rules, and neighborhood search. There is a tendency to develop hybrid methods, in particular by integrating global approaches to local search. There is need to introduce new fields of inspiration.

  14. Empty tracks optimization based on Z-Map model

    Science.gov (United States)

    Liu, Le; Yan, Guangrong; Wang, Zaijun; Zang, Genao

    2017-12-01

    For parts with many features, there are more empty tracks during machining. If these tracks are not optimized, the machining efficiency will be seriously affected. In this paper, the characteristics of the empty tracks are studied in detail. Combining with the existing optimization algorithm, a new tracks optimization method based on Z-Map model is proposed. In this method, the tool tracks are divided into the unit processing section, and then the Z-Map model simulation technique is used to analyze the order constraint between the unit segments. The empty stroke optimization problem is transformed into the TSP with sequential constraints, and then through the genetic algorithm solves the established TSP problem. This kind of optimization method can not only optimize the simple structural parts, but also optimize the complex structural parts, so as to effectively plan the empty tracks and greatly improve the processing efficiency.

  15. Water soluble ions in aerosols (TSP) : Characteristics, sources and seasonal variation over the central Himalayas, Nepal

    Science.gov (United States)

    Tripathee, Lekhendra; Kang, Shichang; Zhang, Qianggong; Rupakheti, Dipesh

    2016-04-01

    Atmspheric pollutants transported from South Asia could have adverse impact on the Himalayan ecosystems. Investigation of aerosol chemistry in the Himalayan region in Nepal has been limited on a temporal and spatial scale to date. Therefore, the water-soluble ionic composition of aerosol using TSP sampler was investigated for a year period from April 2013 to March 2014 at four sites Bode, Dhunche, Lumbini and Jomsom characterized as an urban, rural, semi-urban and remote sites in Nepal. During the study period, the highest concentration of major cation was Ca2+ with an average concentration of 8.91, 2.17, 7.85 and 6.42 μg m-3 and the highest concentration of major anion was SO42- with an average of 10.96, 4.06, 6.85 and 3.30 μg m-3 at Bode, Dhunche, Lumbini and Jomsom respectively. The soluble ions showed the decrease in concentrations from urban to the rural site. Correlations and PCA analysis suggested that that SO42-, NO3- and NH4+ were derived from the anthropogenic sources where as the Ca2+ and Mg2+ were from crustal sources. Our results also suggest that the largest acid neutralizing agent at our sampling sites in the central Himalayas are Ca2+ followed by NH4+. Seasonal variations of soluble ions in aerosols showed higher concentrations during pre-monsoon and winter (dry-periods) due to limited precipitation amount and lower concentrations during the monsoon which can be explained by the dilution effect, higher the precipitation lower the concentration. K+ which is regarded as the tracer of biomss burning had a significant peaks during pre-monsoon season when the forest fires are active around the regions. In general, the results of this study suggests that the atmospheric chemistry is influenced by natural and anthropogenic sources. Thus, soluble ionic concentrations in aerosols from central Himalayas, Nepal can provide a useful database to assess atmospheric environment and its impacts on human health and ecosystem in the southern side of central

  16. Quality strategies implemented within the tourism agency Perfect Tour

    Directory of Open Access Journals (Sweden)

    Madar, A.

    2012-01-01

    Full Text Available The paper presents the quality strategies adopted by the tourism agency Perfect Tour. The most important advantages of the Romanian agency in comparison with its competitors are: the focus on high quality services, cooperation with other international agencies, entering new fields like medical tourism and sole representative of Disneyland Paris. The strategies adopted explain the good financial results even in the period of crisis.

  17. Example Solar Electric Propulsion System asteroid tours using variational calculus

    Science.gov (United States)

    Burrows, R. R.

    1985-01-01

    Exploration of the asteroid belt with a vehicle utilizing a Solar Electric Propulsion System has been proposed in past studies. Some of those studies illustrated multiple asteroid rendezvous with trajectories obtained using approximate methods. Most of the inadequacies of those approximations are overcome in this paper, which uses the calculus of variations to calculate the trajectories and associated payloads of four asteroid tours. The modeling, equations, and solution techniques are discussed, followed by a presentation of the results.

  18. Studi Pengelolaan Paket Wisata One Day Tour Di Kabupaten Semarang

    OpenAIRE

    Rozaqi, Aditama Fauzy; Fitriyah; astrika, Lusia

    2016-01-01

    STUDY OF ONE DAY TOUR MANAGEMENT AS A TOURISMPACKAGES IN SEMARANG DISTRICT.ABSTRACTAutonomy regions is a government affairs transferred to manage their ownhousehold. One of the choices of the government affairs is tourism. Tourism is a new lifestyleindustry which is can fulfill to providing the faster economical growth in the labor sector,income, the standard of living. There's a thousand regions in Indonesia which is has aincredible tourism potential, nevertheless that potential is never be ...

  19. The U.S. commercial air tour industry: a review of aviation safety concerns.

    Science.gov (United States)

    Ballard, Sarah-Blythe

    2014-02-01

    The U.S. Title 14 Code of Federal Regulations defines commercial air tours as "flight[s] conducted for compensation or hire in an airplane or helicopter where a purpose of the flight is sightseeing." The incidence of air tour crashes in the United States is disproportionately high relative to similar commercial aviation operations, and air tours operating under Part 91 governance crash significantly more than those governed by Part 135. This paper reviews the government and industry response to four specific areas of air tour safety concern: surveillance of flight operations, pilot factors, regulatory standardization, and maintenance quality assurance. It concludes that the government and industry have successfully addressed many of these tenet issues, most notably by: advancing the operations surveillance infrastructure through implementation of en route, ground-based, and technological surveillance methods; developing Aeronautical Decision Making and cue-based training programs for air tour pilots; consolidating federal air tour regulations under Part 136; and developing public-private partnerships for raising maintenance operating standards and improving quality assurance programs. However, opportunities remain to improve air tour safety by: increasing the number and efficiency of flight surveillance programs; addressing pilot fatigue with more restrictive flight hour limitations for air tour pilots; ensuring widespread uptake of maintenance quality assurance programs, especially among high-risk operators not currently affiliated with private air tour safety programs; and eliminating the 25-mile exception allowing Part 91 operators to conduct commercial air tours without the safety oversight required of Part 135 operators.

  20. The Tour du Canton defeats the rainy weather

    CERN Multimedia

    Katarina Anthony

    2011-01-01

    On 8 June, over 2200 runners set off from the Route Marie Curie, outside Restaurant No. 1, in the third leg of the 2011 Tour de Canton race. CERN's mixed team held onto the first place in the inter-enterprise competition.   Sigurd Lettow, CERN Director for Administration and General Infrastructure gives the start to runners at the Tour du Canton (8 June 2011). Hosted by the CERN Running Club in collaboration with the communes of Meyrin and Satigny, the race gave runners and their families the chance to pay a flying visit to CERN. “The Tour du Canton races give different areas the opportunity to show off their part of the Canton of Geneva,” says David Nisbet, a member of the Club and one of the organizers of the event. “It was a chance for us to bring unlikely visitors onto the CERN site for a day of competition and fun.” With the starting/finishing line located outside Restaurant No. 1, runners got a look at CERN’s new restaurant extensio...

  1. ANALISIS KEPUASAN WISATAWAN TERHADAP VARIASI PAKET DENPASAR CITY TOUR

    Directory of Open Access Journals (Sweden)

    Shintia Jayanti

    2017-01-01

    Full Text Available Denpasar city tour as one of tourism product in Bali, also developed becomes one of favorite choice for tourist. Since tourism industry product is very dynamic and depends on the environment, it is important to know tourist’s perception and analysis about tourist satisfaction for variety of Denpasar city tour, for making some regulation to improve the product or making some innovation about the product. This research conducted by questionnaire method, also supported with interviews and direct observation. The results analyzed by using Importance-Performance Analysis. The result showed that tourist felt dissatisfaction about the product (Denpasar city tour as shown at the indicator (92,75 percent, and cartecius diagram showed that there are some point that is important for the tourist and should be maintain the performance, such as variation object, facility in the object, reliable information. There are also some point that tourist feel it is important but they feel dissatisfaction about it. There are security checks and security staffs in the object.

  2. An Extension of the Lin-Kernighan-Helsgaun TSP Solver for Constrained Traveling Salesman and Vehicle Routing Problems

    DEFF Research Database (Denmark)

    Helsgaun, Keld

    This report describes the implementation of an extension of the Lin-Kernighan-Helsgaun TSP solver for solving constrained traveling salesman and vehicle routing problems. The extension, which is called LKH-3, is able to solve a variety of well-known problems, including the sequential ordering...... problem (SOP), the traveling repairman problem (TRP), variants of the multiple travel-ing salesman problem (mTSP), as well as vehicle routing problems (VRPs) with capacity, time windows, pickup-and-delivery and distance constraints. The implementation of LKH-3 builds on the idea of transforming...... the problems into standard symmetric traveling salesman problems and handling constraints by means of penalty functions. Extensive testing on benchmark instances from the literature has shown that LKH-3 is effective. Best known solutions are often obtained, and in some cases, new best solutions are found...

  3. Mutagenic and recombinagenic activity of airborne particulates, PM10 and TSP, organic extracts in the Drosophila wing-spot test

    International Nuclear Information System (INIS)

    Rodrigues Dihl, Rafael; Grazielli Azevedo da Silva, Carla; Souza do Amaral, Viviane; Reguly, Maria Luiza; Rodrigues de Andrade, Heloisa Helena

    2008-01-01

    The genotoxicity associated with air pollution in the city of Canoas, Rio Grande do Sul (Brazil), was assessed in November (spring) and January (summer). We applied the somatic mutation and recombination test (SMART) in Drosophila melanogaster in its standard version with normal bioactivation (ST) and in its variant with increased cytochrome P450-dependent biotransformation capacity (HB). The data indicated the genotoxicity of TSP and PM10 collected in November, in both ST and HB crosses. The genotoxic activity of the PM10 material in the spring sample was exclusively associated with the induction of mitotic recombination, whereas the TSP genetic toxicity was due to both recombinational as well as point and/or chromosomal mutation events. Considering PM10 collected in January, a positive response-100% (17.10 m 3 /ml) concentration-was observed in the HB cross, which was not detected in the ST cross. - Drosophila Wing-Spot Test can be used for detection of airborne particulates mutagenesis

  4. Determination of samples with TSP size at PLTU Pacitan, Jawa Timur have been done

    International Nuclear Information System (INIS)

    Rusmanto, Tri; Mulyono; Irianto, Bambang

    2013-01-01

    Sampling is done using equipment High Volume Air Sampler (HVAS) and analysis using gamma spectrometer. Sampling at 3 locations, each location of the sampling carried out 24 hours, air samples on filter conditioned at room temperature, weighed to a contained weight, counting for 24 hours with gamma spectrometer. The result of qualitative and quantitative analysis of filter TSP was contained of locations I Ra-226 = 0,000888 Bq/m 3 , Pb-212 = 0,000356 Bq/m 3 , Pb-214 = 0,000859 Bq/m 3 , Bi-214 = 0,000712 Bq/m 3 , Ac-228 = 0,004447 Bq/m 3 , K-40 = 0,035454 Bq/m 3 ) , Locations II Ra-226 = 0,00113 Bq/m 3 , Pb-212 = 0,00079 Bq/m 3 , Pb-214 = 0,001351 Bq/m 3 , Bi-214 = 0,000433 Bq/m 3 , Ac-228 = 0,007138 Bq/m 3 , K-40 = 0,018532 Bq/m 3 , Locations III Ra-226 = 0,001424 Bq/m 3 , Pb-212 = 0,000208 Bq/m 3 , Pb-214 = 000052 Bq/m 3 , Bi-214 = 0,001408 Bq/m 3 , Ac-228 = 0,008362 Bq/m 3 , K-40 = 0,020536 Bq/m 3 . Radionuclides activity was all still below quality of air enabled by BAPETEN. Become the activities of ambient air of PLTU area still be peaceful enough as settlement area. (author)

  5. THE ABERRANT PROMOTER HYPERMETHYLATION PATTERN OF THE ANTI - ANGIOGENIC TSP1 GENE IN EPITHELIAL OVARIAN CARCINOMA: AN INDIAN STUDY

    Directory of Open Access Journals (Sweden)

    Ramesh

    2015-06-01

    Full Text Available PURPOSE: The promoter hypermethylation patterns of Thrombospodin - 1 gene in 50 EOC patients were studied and the methylation pattern was correlated with various clinic pathological parameters. METHODS: The promoter hypermethylation pattern of the TSP - 1 gene was assessed using nested PCR and Methylation specific PCR. STATISTICAL ANALYSIS: All the available data was statistically analyzed using the Chi square test or Fisher Exact Test on the SPSS software version 22.0 and a value <0.0 5 was considered statistically significant. RESULTS: Forty of the fifty ovarian carcinoma samples reported positive for methylation corresponding to a methylation frequency of 80%. A methylation frequency of 89.2%, 83.3% and 42.8% was observed in malignant , Low malignant potential (borderline and benign sample cohorts. CONCLUSION: From the results drawn from this study, it clearly shows that the anti angiogenic protein TSP - 1 is extensively hypermethylated in ovarian carcinoma and that it accumulates over t he progression of the disease from benign to malignant. As previous reports suggest that there is no evidence of mutation of this gene, promoter hypermethylation may be a crucial factor for the down regulation of the gene. Further by clubbing together the promoter hypermethylation pattern of TSP - 1 gene with hypermethylation patterns of other TSG may provide a better insight into the application of using methylation profiles of TSG as a biomarker in the detection of ovarian carcinoma.

  6. Optimization of Gas Flow Network using the Traveling Salesman ...

    African Journals Online (AJOL)

    The overall goal of this paper is to develop a general formulation for an optimal infrastructure layout design of gas pipeline distribution networks using algorithm developed from the application of two industrial engineering concepts: the traveling salesman problem (TSP) and the nearest neighbor (NN). The focus is on the ...

  7. Socioeconomic Differences in Exposure to Tobacco Smoke Pollution (TSP in Bangladeshi Households with Children: Findings from the International Tobacco Control (ITC Bangladesh Survey

    Directory of Open Access Journals (Sweden)

    Geoffrey T. Fong

    2011-03-01

    Full Text Available This study assessed the pattern of exposure to tobacco smoke pollution (TSP; also known as, secondhand smoke in Bangladeshi households with children and examined the variations in household smoking restrictions and perception of risk for children’s exposure to TSP by socioeconomic status. We interviewed 1,947 respondents from Bangladeshi households with children from the first wave (2009 of the International Tobacco Control (ITC Bangladesh Survey. 43.5% of the respondents had complete smoking restrictions at home and 39.7% were very or extremely concerned about TSP risk to children’s health. Participants with lower level of education were significantly less likely to be concerned about the risk of TSP exposure to children’s health and less likely to adopt complete smoking restrictions at home. Logistic regression revealed that the predictors of concern for TSP exposure risk were educational attainment of 1 to 8 years (OR = 1.94 or 9 years or more (OR = 4.07 and being a smoker (OR = 0.24. The predictors of having complete household smoking restrictions were: urban residence (OR = 1.64, attaining education of 9 years or more (OR = 1.94, being a smoker (OR = 0.40 and being concerned about TSP exposure risk to children (OR = 3.25. The findings show that a high proportion of adults with children at home smoke tobacco at home and their perceptions of risk about TSP exposure to children’s health were low. These behaviours were more prevalent among rural smokers who were illiterate. There is a need for targeted intervention, customized for low educated public, on TSP risk to children’s health and tobacco control policy with specific focus on smoke-free home.

  8. Cytoplasmic Localization of HTLV-1 HBZ Protein: A Biomarker of HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP).

    Science.gov (United States)

    Baratella, Marco; Forlani, Greta; Raval, Goutham U; Tedeschi, Alessandra; Gout, Olivier; Gessain, Antoine; Tosi, Giovanna; Accolla, Roberto S

    2017-01-01

    HTLV-1 is the causative agent of a severe form of adult T cell leukemia/Lymphoma (ATL), and of a chronic progressive neuromyelopathy designated HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). Two important HTLV-1-encoded proteins, Tax-1 and HBZ, play crucial roles in the generation and maintenance of the oncogenic process. Less information is instead available on the molecular and cellular mechanisms leading to HAM/TSP. More importantly, no single specific biomarker has been described that unambiguously define the status of HAM/TSP. Here we report for the first time the finding that HBZ, described until now as an exclusive nuclear protein both in chronically infected and in ATL cells, is instead exclusively localized in the cytoplasm of peripheral blood mononuclear cells (PBMC) from patients suffering of HAM/TSP. Interestingly, at the single cell level, HBZ and Tax-1 proteins are never found co-expressed in the same cell, suggesting the existence of mechanisms of expression uncoupling of these two important HTLV-1 viral products in HAM/TSP patients. Cells expressing cytoplasmic HBZ were almost exclusively found in the CD4+ T cell compartment that was not, at least in a representative HAM/TSP patient, expressing the CD25 marker. Less than 1 percent CD8+ T cells were fond positive for HBZ, while B cells and NK cells were found negative for HBZ in HAM/TSP patients. Our results identify the cytoplasmic localization of HBZ in HAM/TSP patient as a possible biomarker of this rather neglected tropical disease, and raise important hypotheses on the role of HBZ in the pathogenesis of the neuromyelopathy associated to HTLV-1 infection.

  9. Cytoplasmic Localization of HTLV-1 HBZ Protein: A Biomarker of HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP.

    Directory of Open Access Journals (Sweden)

    Marco Baratella

    2017-01-01

    Full Text Available HTLV-1 is the causative agent of a severe form of adult T cell leukemia/Lymphoma (ATL, and of a chronic progressive neuromyelopathy designated HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP. Two important HTLV-1-encoded proteins, Tax-1 and HBZ, play crucial roles in the generation and maintenance of the oncogenic process. Less information is instead available on the molecular and cellular mechanisms leading to HAM/TSP. More importantly, no single specific biomarker has been described that unambiguously define the status of HAM/TSP. Here we report for the first time the finding that HBZ, described until now as an exclusive nuclear protein both in chronically infected and in ATL cells, is instead exclusively localized in the cytoplasm of peripheral blood mononuclear cells (PBMC from patients suffering of HAM/TSP. Interestingly, at the single cell level, HBZ and Tax-1 proteins are never found co-expressed in the same cell, suggesting the existence of mechanisms of expression uncoupling of these two important HTLV-1 viral products in HAM/TSP patients. Cells expressing cytoplasmic HBZ were almost exclusively found in the CD4+ T cell compartment that was not, at least in a representative HAM/TSP patient, expressing the CD25 marker. Less than 1 percent CD8+ T cells were fond positive for HBZ, while B cells and NK cells were found negative for HBZ in HAM/TSP patients. Our results identify the cytoplasmic localization of HBZ in HAM/TSP patient as a possible biomarker of this rather neglected tropical disease, and raise important hypotheses on the role of HBZ in the pathogenesis of the neuromyelopathy associated to HTLV-1 infection.

  10. THE SURVEY OF ATTITUDES OF STUDENTS OF MANAGEMENT TOWARD TRAVEL TOUR PRICES

    OpenAIRE

    Lubomir Karas; Martina Ferencova

    2010-01-01

    When choosing travel tours several factors play an important role such as a destination, purpose of travel tour, the agency's reputation, mode of transportation, accommodation, food, but price and any discounts. This article discusses the survey of attitudes of students of Faculty of Management University of Presov in Presov toward travel tour prices. Príspevok vznikol ako sucast riesenia grantoveho projektu VEGA C. 1/0876/10.

  11. Cloning and analysis of a bifunctional methyltransferase/restriction endonuclease TspGWI, the prototype of a Thermus sp. enzyme family

    Directory of Open Access Journals (Sweden)

    Zylicz-Stachula Agnieszka

    2009-05-01

    Full Text Available Abstract Background Restriction-modification systems are a diverse class of enzymes. They are classified into four major types: I, II, III and IV. We have previously proposed the existence of a Thermus sp. enzyme family, which belongs to type II restriction endonucleases (REases, however, it features also some characteristics of types I and III. Members include related thermophilic endonucleases: TspGWI, TaqII, TspDTI, and Tth111II. Results Here we describe cloning, mutagenesis and analysis of the prototype TspGWI enzyme that recognises the 5'-ACGGA-3' site and cleaves 11/9 nt downstream. We cloned, expressed, and mutagenised the tspgwi gene and investigated the properties of its product, the bifunctional TspGWI restriction/modification enzyme. Since TspGWI does not cleave DNA completely, a cloning method was devised, based on amino acid sequencing of internal proteolytic fragments. The deduced amino acid sequence of the enzyme shares significant sequence similarity with another representative of the Thermus sp. family – TaqII. Interestingly, these enzymes recognise similar, yet different sequences in the DNA. Both enzymes cleave DNA at the same distance, but differ in their ability to cleave single sites and in the requirement of S-adenosylmethionine as an allosteric activator for cleavage. Both the restriction endonuclease (REase and methyltransferase (MTase activities of wild type (wt TspGWI (either recombinant or isolated from Thermus sp. are dependent on the presence of divalent cations. Conclusion TspGWI is a bifunctional protein comprising a tandem arrangement of Type I-like domains; particularly noticeable is the central HsdM-like module comprising a helical domain and a highly conserved S-adenosylmethionine-binding/catalytic MTase domain, containing DPAVGTG and NPPY motifs. TspGWI also possesses an N-terminal PD-(D/EXK nuclease domain related to the corresponding domains in HsdR subunits, but lacks the ATP-dependent translocase module

  12. AVATAR -- Adaptive Visualization Aid for Touring And Recovery

    Energy Technology Data Exchange (ETDEWEB)

    L. O. Hall; K. W. Bowyer; N. Chawla; T. Moore, Jr.; W. P. Kegelmeyer

    2000-01-01

    This document provides a report on the initial development of software which uses a standard visualization tool to determine, label and display salient regions in large 3D physics simulation datasets. This software uses parallel pattern recognition behind the scenes to handle the huge volume of data. This software is called AVATAR (Adaptive Visualization Aid for Touring and Recovery). It integrates approaches to gathering labeled training data, learning from large training sets utilizing parallelism and the final display of salient data in unseen visualization data sets. The paper uses vorticity fields for a large-eddy simulation to illustrate the method.

  13. A Voice Operated Tour Planning System for Autonomous Mobile Robots

    Directory of Open Access Journals (Sweden)

    Charles V. Smith Iii

    2010-06-01

    Full Text Available Control systems driven by voice recognition software have been implemented before but lacked the context driven approach to generate relevant responses and actions. A partially voice activated control system for mobile robotics is presented that allows an autonomous robot to interact with people and the environment in a meaningful way, while dynamically creating customized tours. Many existing control systems also require substantial training for voice application. The system proposed requires little to no training and is adaptable to chaotic environments. The traversable area is mapped once and from that map a fully customized route is generated to the user

  14. STRATEGI PEMASARAN PAKET WISATA PADA PT. PANDAWA LIMA TOUR AND TRAVEL INDONESIA DI DENPASAR

    Directory of Open Access Journals (Sweden)

    I Gede Adhi Suputra Arimbawa PG.

    2017-01-01

    Full Text Available This research is about the marketing strategies implemented by PT. Pandawa Lima Tour and Travel tour packages. Company offers tour packages in Bali and beyond Bali tour packages with variety of facilities. As a common general company, PT. Pandawa Lima Tour and Travel has the objective to make profit and trying to satisfy consumers. This research aims to determine the marketing strategy package in PT. Pandawa Lima Tour and Travel tour package in Denpasar. The data collection method in research carried out by the method of observation, in-depth interviews, library research, and technique documentation. The data analysis technique used is descriptive qualitative combined with the SWOT approach. Discussion of the results of the marketing strategy adopted by the PT. Pandawa Lima Tour and Travel is SO strategy by increasing sales promotion to target markets, enhance cooperation with hotels and travel agents and maintain the diversity and innovation of product and service quality. ST strategies to further enhance cooperation with other travel agencies, and improve service quality. WO strategies to enhance the promotion through the mass media, and printing brochures, expanding market segments and improve the quality of human resources in education and training. While WT strategy by increasing promotional activities and improve human resources. Based on the results of the discussion, can give advice - advice on marketing strategies in PT. Pandawa Lima Tour and Travel tour packages that maintain good relations with the company's existing transport and suggest PT. Pandawa Lima Tour and Travel to their own transport, improving education and training for employees and appropriate compensation, as well as updating the architecture buildings and office equipment.

  15. Household/Zonal Socioeconomic Characteristics and Tour Making: Case of Richmond/Tri-Cities Model Region in Virginia

    Directory of Open Access Journals (Sweden)

    Xueming CHEN

    2014-06-01

    Full Text Available This paper statistically assesses the impacts of household/zonal socio economic characteristics on tour making within the Richmond/Tri-Cities Model Region, Virginia, United States, based on the dataset made available through the 2009 Virginia National Household Travel Survey (NHTS Add-On Program. The tour analysis distinguishes nine tour types (three simple tours and six complex tours stratified by aggregate tour purposes of work (including school and other subsistence activities, maintenance and discretionary. A series of regression model runs have yielded the following conclusions: First, at aggregate level, the number of drivers, median household income, household size, number of workers, and zonal walking modal share are statistically significant and positively impact tour frequency. Tour length and complexity are positively related to household income and number of vehicles, but negatively related to zonal walking modal share. Second, at an individual tour type level, each tour type’s frequency/length/complexity is impacted by a different set of household/zonal socioeconomic characteristics. Zonal socioeconomic characteristics have little or no impacts on household tour making. It is recognized that many unknown factors may also have impacted tour activities, which require further in-depth studies in order to better explain complex tours.

  16. LEVERAGING EXISTING HERITAGE DOCUMENTATION FOR ANIMATIONS: SENATE VIRTUAL TOUR

    Directory of Open Access Journals (Sweden)

    A. Dhanda

    2017-08-01

    Full Text Available The use of digital documentation techniques has led to an increase in opportunities for using documentation data for valorization purposes, in addition to technical purposes. Likewise, building information models (BIMs made from these data sets hold valuable information that can be as effective for public education as it is for rehabilitation. A BIM can reveal the elements of a building, as well as the different stages of a building over time. Valorizing this information increases the possibility for public engagement and interest in a heritage place. Digital data sets were leveraged by the Carleton Immersive Media Studio (CIMS for parts of a virtual tour of the Senate of Canada. For the tour, workflows involving four different programs were explored to determine an efficient and effective way to leverage the existing documentation data to create informative and visually enticing animations for public dissemination: Autodesk Revit, Enscape, Autodesk 3ds Max, and Bentley Pointools. The explored workflows involve animations of point clouds, BIMs, and a combination of the two.

  17. Yucca Mountain public tours: Can they impact public opinion?

    International Nuclear Information System (INIS)

    Reilly, B.; Austin, P.

    1991-01-01

    The Yucca Mountain site in Nevada was selected by Congress in 1987 as the only site for the US Department of Energy (DOE) to study for suitability as a high-level radioactive waste repository. Several years of site characterization studies are needed to determine if the site is suitable. However, DOE's study of the site is one of the most intensely opposed federal programs today. The fight against DOE's effort to study the repository leads the political agendas of Nevada's governor and Congressional delegation. The politicians and the press have been the primary sources of information for Nevada citizens on the Yucca Mountain site characterization program. However, there is a more direct source of factual information regarding the program - the site itself and the participating scientists. The DOE is offering Nevada citizens the opportunity to form their own opinions by touring the Yucca Mountain site and interacting with DOE scientists and engineers. Feedback from monthly tours conducted from March to June 1991 has indicated substantial support from Nevada citizens for DOE's study of the site. In fact, a surprising number of citizens have indicated that the opportunity to gather information and formulate their own opinions led them to change their opinions

  18. Leveraging Existing Heritage Documentation for Animations: Senate Virtual Tour

    Science.gov (United States)

    Dhanda, A.; Fai, S.; Graham, K.; Walczak, G.

    2017-08-01

    The use of digital documentation techniques has led to an increase in opportunities for using documentation data for valorization purposes, in addition to technical purposes. Likewise, building information models (BIMs) made from these data sets hold valuable information that can be as effective for public education as it is for rehabilitation. A BIM can reveal the elements of a building, as well as the different stages of a building over time. Valorizing this information increases the possibility for public engagement and interest in a heritage place. Digital data sets were leveraged by the Carleton Immersive Media Studio (CIMS) for parts of a virtual tour of the Senate of Canada. For the tour, workflows involving four different programs were explored to determine an efficient and effective way to leverage the existing documentation data to create informative and visually enticing animations for public dissemination: Autodesk Revit, Enscape, Autodesk 3ds Max, and Bentley Pointools. The explored workflows involve animations of point clouds, BIMs, and a combination of the two.

  19. Incidence of chromosomal aberrations and micronuclei in cave tour guides.

    Science.gov (United States)

    Bilban, M; Bilban-Jakopin, C; Vrhovec, S

    2001-01-01

    An analysis of structural chromosomal aberrations (SCA) and micronucleus tests (MN) were performed in 38 subjects, cave tour guides and in appropriate control group. The dominant type of chromosomal aberrations in tourist guides were chromosomal breaks (0.013 per cell) and acentric fragments (0.011 per cell). In the control group, these aberrations were present up to 0.008 on cells. Considering the analysed cells of the guides in total (33,556), the incidence of dicentric and rings range is below 0.0008 on cells, even though three dicentric and ring chromosoms were found already in the first 1000 in vitro metaphases of some guides. Only 0.0003 dicentrics and neither other translocations were found in control group (ambiental exposure). The incidence of micronuclei in cytokinesis blocked lymphocytes ranged from 12-32 per 500 CB cells in the cave tour guides and from 4-11 per 500 CB cells in control group. Measurements of radon and its daughters were performed at different locations in the cave. Annual doses from 40-60 mSv were estimated per 2000 work hours for cave guides. The changes found in the genome of somatic cells may be related to the exposure doses of radon and its daughters, although smoking should not be ignored.

  20. V.A. Gorodtsov and Kazan: tour 1920

    Directory of Open Access Journals (Sweden)

    Kuzminykh Sergey V.

    2014-12-01

    Full Text Available A fragment of an archival document is published, that is connected to the September 8-12, 1920, stay in Kazan of V.A. Gorodtsov, who headed the Archaeological Subdepartment with the Museum Department of the RSFSR People’s Commissariat for Education, in the framework of his inspecting tour around the towns of the Volga and Urals region. The document is a diary, and its entries reflect information about the tour and its results that had not been exhaustively reflected in official documentation. It narrates about meetings, polemic exchanges, Gorodtsov’s addresses to scientists and the public, his impressions of the archaeological investigations in the regions, and the state of the museums and collections. V.A. Gorodtsov’s encounters and personal contacts with B.F. Adler, N.F. Katanov, M.G. Hudyakov and other researchers had played a positive role in archaeology development in the Volga-Kama region during the hardest times after the revolution.

  1. STRATEGI BERSAING BIRO PERJALANAN WISATA ALINDO DEWATA TOURS BALI

    Directory of Open Access Journals (Sweden)

    Nelsye Natalina Lintong

    2015-09-01

    Full Text Available Alindo Dewata Tours Bali as an inbound tours companydeals with the competitors by applying competitive strategy.Nevertheless the competitive strategy applied is not maximumyet. It is apparently seen at the average growth of touristsnumber handled since 2004-2013 by the company only 5,97 %.Therefore, this study has the objective to know what internalexternal factors that give influences and competitive strategy tobe applied in the company. This research using analysis toolsof Internal Factor Evaluation (IFE matrix, External FactorEvaluation (EFE matrix for general strategy, Internal External(IE matrix, Strength Weakness Opportunity Threat (SWOTmatrix for alternative strategy and Quantitative StrategicPlanning Matrix (QSPM for priority strategy. The result of IFEmatrix indicates bundle pricing policy as the prime strengthand the application of the management information system notmaximum as the prime weakness. EFE matrix indicates qualitystrategy contributes the service as prime opportunity and thedependency on the foreign travel agencies as prime threat.Based on IE matrix, the company’s position is at five (V levelfor resistance and endurance strategy. SWOT matrix indicateseight competitive strategic alternatives. Suggested first priorityby QSPM is to develop market segment, both overseas anddomestic market.

  2. Indentations and Starting Points in Traveling Sales Tour Problems: Implications for Theory

    Science.gov (United States)

    MacGregor, James N.

    2012-01-01

    A complete, non-trivial, traveling sales tour problem contains at least one "indentation", where nodes in the interior of the point set are connected between two adjacent nodes on the boundary. Early research reported that human tours exhibited fewer such indentations than expected. A subsequent explanation proposed that this was because…

  3. 26 CFR 1.513-7 - Travel and tour activities of tax exempt organizations.

    Science.gov (United States)

    2010-04-01

    ... within the UnitedStates. The study tours are conducted by teachers and other personnel certified by the... organization. The examples are as follows: Example 1. O, a university alumni association, is exempt from... faculty member of O's related university frequently joins the tour as a guest of the alumni association...

  4. Emotional exhaustion and job satisfaction of tour guides in rural areas

    Directory of Open Access Journals (Sweden)

    Anđelković Željko

    2017-01-01

    Full Text Available The purpose of this study was to determinate the job satisfaction and emotional exhaustion of tour guides in rural areas and to show how these two concepts are related to each other. A total of 102 tour guides, who lead tours or have experience in leading tours in rural areas took part in the questionnaire and the results were given and processed in SPSS version 17. Tour guides have a great importance in interpretation of rural areas as well as a significant role in presenting local customs and products in rural tourism. Exploring their satisfaction but also emotional exhaustion is of paramount importance for maintaining their excellence in interpretation of these areas. The results indicate that job satisfaction is still not on satisfying level, while emotional exhaustion is under acceptable limits. The results also showed that there is a negative connection between these two concepts. The obtained data should be beneficial not only to tour-operators but also to other tourism-related companies dealing with FDA (Front Desk Activities and employees in rural tourism: the data about job satisfaction and emotional exhaustion of tour guides can be used in developing management and work motivation strategies. The profound insight in job satisfaction and emotional exhaustion is important in order to achieve business excellence of tour guides in rural areas.

  5. 75 FR 53980 - Notice of Field Tours for the Pinedale Anticline Working Group

    Science.gov (United States)

    2010-09-02

    ... Project Area (PAPA) 2008 Supplemental Environmental Impact Statement (SEIS), and the Pinedale Anticline...) PAWG will conduct field tours of the Pinedale Anticline Project Area (PAPA). Tours are open to the... . SUPPLEMENTARY INFORMATION: The PAWG was established by the EIS ROD for the PAPA on July 27, 2000, and carried...

  6. Report of tour of duty to the USA: 14 October 1999 to 26 October 1999

    CSIR Research Space (South Africa)

    Steyn, WJvdM

    1999-11-01

    Full Text Available This report describes a tour of duty undertaken to the USA in October 1999. The objectives of this tour of duty were to attend the 1999 Reno APT Conference, visit to smart material companies and visit the Palmdale HVS site....

  7. Interactive Character as a Virtual Tour Guide to an Online Museum Exhibition.

    Science.gov (United States)

    de Almeida, Pilar; Yokoi, Shigeki

    Online museums could benefit from digital "lifelike" characters in order to guide users to virtual tours and to customize the tour information to users' interests. Digital characters have been explored in online museum web sites with different degrees of interaction and modes of communication. Such research, however, does not explore…

  8. Optimally Scheduling Distribution of the MH-60S Helicopter and Pilots to Combat Support (HC) Squadrons

    National Research Council Canada - National Science Library

    Culver, Cory

    2002-01-01

    ... (Optimal Transition HC Allocation Model) that minimizes lost flying days. OTHCAM takes into account variable training durations, travel times and tour lengths as well as manpower and aircraft constraints...

  9. Lake Mead National Recreational Area air tour management plan and planning and National Environmental Policy Act scoping document

    Science.gov (United States)

    2004-04-19

    The Federal Aviation Administration (FAA), in cooperation with the National Park Service (NPS), has initiated the development of an Air Tour Management Plan (ATMP) for Lake Mead National Recreation Area (LAME) pursuant to the National Parks Air Tour ...

  10. Structure and dynamics of the peptide strand KRFK from the thrombospondin TSP-1 in water.

    Science.gov (United States)

    Taleb Bendiab, W; Benomrane, B; Bounaceur, B; Dauchez, M; Krallafa, A M

    2018-02-14

    Theoretical investigations of a solute in liquid water at normal temperature and pressure can be performed at different levels of theory. Static quantum calculations as well as classical and ab initio molecular dynamics are used to completely explore the conformational space for large solvated molecular systems. In the classical approach, it is essential to describe all of the interactions of the solute and the solvent in detail. Water molecules are very often described as rigid bodies when the most commonly used interaction potentials, such as the SPCE and the TIP4P models, are employed. Recently, a physical model based upon a cluster of rigid water molecules with a tetrahedral architecture (AB 4 ) was proposed that describes liquid water as a mixture of both TIP4P and SPCE molecular species that occur in the proportions implied by the tetrahedral architecture (one central molecule versus four outer molecules; i.e., 20% TIP4P versus 80% SPCE molecules). In this work, theoretical spectroscopic data for a peptide strand were correlated with the structural properties of the peptide strand solvated in water, based on data calculated using different theoretical approaches and physical models. We focused on a particular peptide strand, KRFK (lysine-arginine-phenylalanine-lysine), found in the thrombospondin TSP-1, due to its interesting properties. As the activity and electronic structure of this system is strongly linked to its structure, we correlated its structure with charge-density maps obtained using different semi-empirical charge Q eq equations. The structural and thermodynamic properties obtained from classical simulations were correlated with ab initio molecular dynamics (AIMD) data. Structural changes in the peptide strand were rationalized in terms of the motions of atoms and groups of atoms. To achieve this, conformational changes were investigated using calculated infrared spectra for the peptide in the gas phase and in water solvent. The calculated AIMD

  11. Constructing a Travel Risks’ Evaluation Model for Tour Freelancers Based on the ANP Approach

    Directory of Open Access Journals (Sweden)

    Chin-Tsai Lin

    2016-01-01

    Full Text Available This study constructs a new travel risks’ evaluation model for freelancers to evaluate and select tour groups by considering the interdependencies of the evaluation criteria used. First of all, the proposed model adopts the Nominal Group Technique (NGT to identify suitable evaluation criteria for evaluating travel risks. Six evaluation criteria and 18 subcriteria are obtained. The six evaluation criteria are financial risk, transportation risk, social risk, hygiene risk, sightseeing spot risk, and general risk for freelancer tour groups. Secondly, the model uses the analytic network process (ANP to determine the relative weight of the criteria. Finally, examples of group package tours (GPTs are used to demonstrate the travel risk evaluation process for this model. The results show that the Tokyo GPT is the best group tour. The proposed model helps freelancers to effectively evaluate travel risks and decision-making, making it highly applicable to academia and tour groups.

  12. STRATEGI PEMASARAN PAKET WISATA MELALUI MEDIA ONLINE DI TRULY ASIA TOUR AND TRAVEL

    Directory of Open Access Journals (Sweden)

    Ade Prawita Sari

    2016-07-01

    Full Text Available The purpose of this research is to find out the marketing strategy of tour package at Truly Asia tour and travel through online system. SWOT analysis is the method for this research and implemented into SWOT matrix table to find out the right strategy for the tour package at Truly Asia tour and travel through online system. Now days Marketing strategy through online system very popular and the conclusion of this research is Truly Asia as a company need to improve their variant of tour package in order to make tourist more interest to visit the company website. Besides that, increase the cheap price must be accompanied by quality of products to suit with the target, providing accurate information on the website is rather tourist confidence crisis, as well as using the internet connection system that has good quality, in order to minimize system error.

  13. Comparison of HTLV-I Proviral Load in Adult T Cell Leukemia/Lymphoma (ATL), HTLV-I-Associated Myelopathy (HAM-TSP) and Healthy Carriers.

    Science.gov (United States)

    Akbarin, Mohammad Mehdi; Rahimi, Hossein; Hassannia, Tahereh; Shoja Razavi, Ghazaleh; Sabet, Faezeh; Shirdel, Abbas

    2013-03-01

    Human T Lymphocyte Virus Type one (HTLV-I) is a retrovirus that infects about 10-20 million people worldwide. Khorasan province in Iran is an endemic area. The majority of HTLV-I-infected individuals sustain healthy carriers but small proportion of infected population developed two progressive diseases: HAM/TSP and ATL. The proviral load could be a virological marker for disease monitoring, therefore in the present study HTLV-I proviral load has been evaluated in ATL and compared to HAM/TSP and healthy carriers. In this case series study, 47 HTLV-I infected individuals including 13 ATL, 23 HAM/TSP and 11 asymptomatic subjects were studied. Peripheral blood mononuclear cells (PBMCs) were investigated for presence of HTLV-I DNA provirus by PCR using LTR and Tax fragments. Then in infected subjects, HTLV-I proviral load was measured using real time PCR TaqMan method. The average age of patients in ATL was 52±8, in HAM/TSP 45.52±15.17 and in carrier's 38.65±14.9 years which differences were not statistically significant. The analysis of data showed a significant difference in mean WBC among study groups (ATL vs HAM/TSP and carriers P=0.0001). Moreover, mean HTLV-I proviral load was 11967.2 ± 5078, 409 ± 71.3 and 373.6 ± 143.3 in ATL, HAM/TSP and Healthy Carriers, respectively. The highest HTLV-I proviral load was measured in ATL group that had a significant correlation with WBC count (R=0.495, P=0.001). The proviral load variations between study groups was strongly significant (ATL vs carrier P=0.0001; ATL vs HAM/TSP P= 0.0001 and HAM/TSP vs carriers P< 0.05). Conclusion : The present study demonstrated that HTLV-I proviral load was higher in ATL group in comparison with HAM/TSP and healthy carriers. Therefore, HTLV-I proviral load is a prognostic factor for development of HTLV-I associated diseases and can be used as a monitoring marker for the efficiency of therapeutic regime.

  14. WE-C-TOUR-I-01: Dosimters for QC in Diagnostic Imaging

    International Nuclear Information System (INIS)

    Jiang, X.

    2016-01-01

    Tour Leader: Xia Jiang, Ohio State University, Columbus, OH Tour Guides: Xia Jiang, Ohio State University, Columbus, OH Kevin Little, The University of Chicago, Chicago, IL Adrien Sanchez, University of Chicago, Chicago, IL Participating Vendors: IBA PTW - New York Radcal Corporation RTI Electronics, Inc. Exhibit Hall Guided Tours is a new program launching this year at the Annual Meeting. The Guided Tours are designed to enhance the interaction between meeting attendees and exhibitors. This year’s Imaging Guided Tours are organized around the theme of dosimeters for quality control in diagnostic imaging. Tours will begin with an introduction and background given by Dr. Xia Jiang, the Tour Leader. The introduction will cover the types and properties of different radiation dosimeters used for quality assurance in clinical radiology. Attendees will then break into smaller groups, each lead by an AAPM-member Tour Guide. The tour groups will visit the exhibit booths of vendors who provide appropriate dosimeters, and a vendor representative will give a presentation to the group about their particular product(s). The vendor representatives as well as the Tour Guides will be available to answer questions. Outline: Types and properties of radiation detectors and dosimeters Ionization chamber dosimeters Solid state dosimeters Dosimeter calibration: Primary and secondary standards dosimetry laboratories Instruments for measuring tube voltage and exposure time Vendor presentations will likely cover features and innovations of different dosimeter systems, as well as their practical use. Learning Objectives: Understand the types and properties of different instrumentations used for quality control in diagnostic imaging. Understand the process of dosimeter calibration. Gain familiarity with the latest commercial dosimeter systems from different vendors.

  15. WE-C-TOUR-I-01: Dosimters for QC in Diagnostic Imaging

    Energy Technology Data Exchange (ETDEWEB)

    Jiang, X. [Ohio State University (United States)

    2016-06-15

    Tour Leader: Xia Jiang, Ohio State University, Columbus, OH Tour Guides: Xia Jiang, Ohio State University, Columbus, OH Kevin Little, The University of Chicago, Chicago, IL Adrien Sanchez, University of Chicago, Chicago, IL Participating Vendors: IBA PTW - New York Radcal Corporation RTI Electronics, Inc. Exhibit Hall Guided Tours is a new program launching this year at the Annual Meeting. The Guided Tours are designed to enhance the interaction between meeting attendees and exhibitors. This year’s Imaging Guided Tours are organized around the theme of dosimeters for quality control in diagnostic imaging. Tours will begin with an introduction and background given by Dr. Xia Jiang, the Tour Leader. The introduction will cover the types and properties of different radiation dosimeters used for quality assurance in clinical radiology. Attendees will then break into smaller groups, each lead by an AAPM-member Tour Guide. The tour groups will visit the exhibit booths of vendors who provide appropriate dosimeters, and a vendor representative will give a presentation to the group about their particular product(s). The vendor representatives as well as the Tour Guides will be available to answer questions. Outline: Types and properties of radiation detectors and dosimeters Ionization chamber dosimeters Solid state dosimeters Dosimeter calibration: Primary and secondary standards dosimetry laboratories Instruments for measuring tube voltage and exposure time Vendor presentations will likely cover features and innovations of different dosimeter systems, as well as their practical use. Learning Objectives: Understand the types and properties of different instrumentations used for quality control in diagnostic imaging. Understand the process of dosimeter calibration. Gain familiarity with the latest commercial dosimeter systems from different vendors.

  16. 1964 Great Alaska Earthquake: a photographic tour of Anchorage, Alaska

    Science.gov (United States)

    Thoms, Evan E.; Haeussler, Peter J.; Anderson, Rebecca D.; McGimsey, Robert G.

    2014-01-01

    On March 27, 1964, at 5:36 p.m., a magnitude 9.2 earthquake, the largest recorded earthquake in U.S. history, struck southcentral Alaska (fig. 1). The Great Alaska Earthquake (also known as the Good Friday Earthquake) occurred at a pivotal time in the history of earth science, and helped lead to the acceptance of plate tectonic theory (Cox, 1973; Brocher and others, 2014). All large subduction zone earthquakes are understood through insights learned from the 1964 event, and observations and interpretations of the earthquake have influenced the design of infrastructure and seismic monitoring systems now in place. The earthquake caused extensive damage across the State, and triggered local tsunamis that devastated the Alaskan towns of Whittier, Valdez, and Seward. In Anchorage, the main cause of damage was ground shaking, which lasted approximately 4.5 minutes. Many buildings could not withstand this motion and were damaged or collapsed even though their foundations remained intact. More significantly, ground shaking triggered a number of landslides along coastal and drainage valley bluffs underlain by the Bootlegger Cove Formation, a composite of facies containing variably mixed gravel, sand, silt, and clay which were deposited over much of upper Cook Inlet during the Late Pleistocene (Ulery and others, 1983). Cyclic (or strain) softening of the more sensitive clay facies caused overlying blocks of soil to slide sideways along surfaces dipping by only a few degrees. This guide is the document version of an interactive web map that was created as part of the commemoration events for the 50th anniversary of the 1964 Great Alaska Earthquake. It is accessible at the U.S. Geological Survey (USGS) Alaska Science Center website: http://alaska.usgs.gov/announcements/news/1964Earthquake/. The website features a map display with suggested tour stops in Anchorage, historical photographs taken shortly after the earthquake, repeat photography of selected sites, scanned documents

  17. Digital Repatriation: Constructing a Culturally Responsive Virtual Museum Tour

    Directory of Open Access Journals (Sweden)

    Loriene Roy、Mark Christal

    2002-04-01

    Full Text Available

    頁次:14-18

    This paper describe a project that involved educators and three Native American communities in the construction of a virtual tour now available on the Web site of the National Museum of the American Indian(http://www. conexus.si.edu/. In fall 1998, the Pueblo of Laguna Department of Education, the College of Education and Graduate School of Library and Information Science at The University of Texas at Austin, and the Smithsonians National Museum of the American Indian (NMAI began the first collaboration that brought Native American students, teachers, and cultural representatives to the NMAI George Gustav Heye Center in New York City. The virtual tour makes extensive use of QuickTime Virtual Reality (QTVR. The panoramas of the exhibition space serve as an interface for accessing the featured objects selected by the students. Clicking on a hot spot over the museum display of a featured object causes the QTVR object to load in a separate Webpage frame accompanied by an interpreted essay written by a student. Clickable floor plans of the exhibition- space offer another method of navigating the virtual tour and accessing the virtual objects.

  18. An integrated TSP-GA with EOL cost model for selecting the best EOL option

    OpenAIRE

    Zakri Ghazalli; Atsuo Murata

    2011-01-01

    This paper presents our research works on integrating design for disassembly with cost model for end-of-life (EOL) product. This paper has two objectives. The first objective is to optimize disassembly sequence of the EOL product. We integrate a traveling salesman problem approach with genetic algorithm in finding the optimal disassembly sequence for disassembling the EOL product. Based on this optimal sequence, the second objective is to identify the best EOL option. We employ EOL profits an...

  19. Mutagenic and recombinagenic activity of airborne particulates, PM10 and TSP, organic extracts in the Drosophila wing-spot test

    Energy Technology Data Exchange (ETDEWEB)

    Rodrigues Dihl, Rafael [Programa de Pos Graduacao em Genetica e Biologia Molecular (PPGBM), Universidade Federal do Rio Grande do Sul, Porto Alegre, RS (Brazil); Grazielli Azevedo da Silva, Carla [Instituto de Quimica, Departamento de Quimica Organica, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS (Brazil); Souza do Amaral, Viviane; Reguly, Maria Luiza [Laboratorio de Diagnostico da Toxicidade Genetica (TOXIGEN), Programa de Pos Graduacao em Genetica e Toxicologia Aplicada (PPGGTA), Universidade Luterana do Brasil - ULBRA, Avenida Farroupilha 8001, 92420280 Canoas, RS (Brazil); Rodrigues de Andrade, Heloisa Helena [Laboratorio de Diagnostico da Toxicidade Genetica (TOXIGEN), Programa de Pos Graduacao em Genetica e Toxicologia Aplicada (PPGGTA), Universidade Luterana do Brasil -ULBRA, Avenida Farroupilha 8001, 92420280 Canoas, RS (Brazil)], E-mail: heloisa@ulbra.br

    2008-01-15

    The genotoxicity associated with air pollution in the city of Canoas, Rio Grande do Sul (Brazil), was assessed in November (spring) and January (summer). We applied the somatic mutation and recombination test (SMART) in Drosophila melanogaster in its standard version with normal bioactivation (ST) and in its variant with increased cytochrome P450-dependent biotransformation capacity (HB). The data indicated the genotoxicity of TSP and PM10 collected in November, in both ST and HB crosses. The genotoxic activity of the PM10 material in the spring sample was exclusively associated with the induction of mitotic recombination, whereas the TSP genetic toxicity was due to both recombinational as well as point and/or chromosomal mutation events. Considering PM10 collected in January, a positive response-100% (17.10 m{sup 3}/ml) concentration-was observed in the HB cross, which was not detected in the ST cross. - Drosophila Wing-Spot Test can be used for detection of airborne particulates mutagenesis.

  20. An exact "Tour de France" passes through CERN

    CERN Multimedia

    CERN Bulletin

    2011-01-01

    In August 2011, the renowned French mountaineer Lionel Daudet set off from Mont Blanc on a "Tour de la France exacte",  strictly following the 5,000 km of land borders and coastline without using a single motorised vehicle. And about a week into his expedition, the French border led him… to CERN of course… where he described his experience as out of the ordinary.   Lionel Daudet at one of the posts marking the French border in Meyrin (next to the Linac 4 building).  The words "out of the ordinary" are not used lightly by a man who has scaled France's highest peaks in extreme conditions and conquered the world's greatest climbs (mainly solo), from Alaska to Patagonia. "I had never visited a physics lab before today," confesses Lionel Daudet, sitting at a table in the CERN cafeteria. "You get the feeling that knowledge is being built here. When I crossed this particular border...

  1. Tour du canton de Genève 2017

    CERN Multimedia

    CERN Running club

    2017-01-01

    Pour rappel, le tour du canton est un évènement incontournable pour les coureurs de la région genevoise. Une épreuve qui a lieu le mercredi soir et qui se déroule sur 4 étapes.  Le Running Club du CERN a encore brillé cette année en obtenant de très bons résultats en individuel et surtout par équipe. L’équipe femme monte sur la première marche du podium (voir photo jointe) Les deux premières équipes hommes se classent 2e et 4e sur 51 équipes classées. Voir classement complet ici : http://www.sport-info.com/i_resultats.php?id=113

  2. Gregory Merkel Tours Marshall Space Flight Center (MSFC)

    Science.gov (United States)

    1972-01-01

    Gregory A. Merkel (left), high school student from Springfield, Massachusetts, is pictured here with Harry Coons of the Marshall Space Flight Center (MSFC) during a visit to the center. Merkel was among 25 winners of a contest in which some 3,500 high school students proposed experiments for the following year's Skylab mission. The nationwide scientific competition was sponsored by the National Science Teachers Association and the National Aeronautics and Space Administration (NASA). The winning students, along with their parents and sponsor teachers, visited MSFC where they met with scientists and engineers, participated in design reviews for their experiments, and toured MSFC facilities. Of the 25 students, 6 did not see their experiments conducted on Skylab because the experiments were not compatible with Skylab hardware and timelines. Of the 19 remaining, 11 experiments required the manufacture of additional equipment.

  3. Authoring Tours of Geospatial Data With KML and Google Earth

    Science.gov (United States)

    Barcay, D. P.; Weiss-Malik, M.

    2008-12-01

    As virtual globes become widely adopted by the general public, the use of geospatial data has expanded greatly. With the popularization of Google Earth and other platforms, GIS systems have become virtual reality platforms. Using these platforms, a casual user can easily explore the world, browse massive data-sets, create powerful 3D visualizations, and share those visualizations with millions of people using the KML language. This technology has raised the bar for professionals and academics alike. It is now expected that studies and projects will be accompanied by compelling, high-quality visualizations. In this new landscape, a presentation of geospatial data can be the most effective form of advertisement for a project: engaging both the general public and the scientific community in a unified interactive experience. On the other hand, merely dumping a dataset into a virtual globe can be a disorienting, alienating experience for many users. To create an effective, far-reaching presentation, an author must take care to make their data approachable to a wide variety of users with varying knowledge of the subject matter, expertise in virtual globes, and attention spans. To that end, we present techniques for creating self-guided interactive tours of data represented in KML and visualized in Google Earth. Using these methods, we provide the ability to move the camera through the world while dynamically varying the content, style, and visibility of the displayed data. Such tours can automatically guide users through massive, complex datasets: engaging a broad user-base, and conveying subtle concepts that aren't immediately apparent when viewing the raw data. To the casual user these techniques result in an extremely compelling experience similar to watching video. Unlike video though, these techniques maintain the rich interactive environment provided by the virtual globe, allowing users to explore the data in detail and to add other data sources to the presentation.

  4. Pretour in-servicing of teachers and students: Effects on tour program

    International Nuclear Information System (INIS)

    Walker, R.J.

    1989-01-01

    Plant tour programs constitute a major educational outreach program for nuclear facilities. As a result of observing exhibits, touring facilities, and interacting with plant personnel, students become more informed and receptive to the nuclear energy issue. With this new information, students have a better understanding of the plant, its operation, and its place in their future. The management of the Perry power plant in Perry, Ohio, has recognized the need for, and the benefits to be derived from, a plant tour program for students. These students are tomorrow's customers and voters. It has also recognized the problems inherent in providing such tours; for instance, a visit to a nuclear power plant can overwhelm unprepared students. Another problem is that resource materials regarding nuclear energy that are available to educators are often outdated. To address this lack of educational material and to improve the educational quality of the tour program, the Perry plant has developed a three-step program. This program includes a new energy education center and a walking tour of its unfinished unit 2 facility. Updated materials are delivered to the classroom familiarizing both teachers and students with the concepts and terminology that will be used during their visit. As a result of the familiarization, the students leave the tour experience with a greater understanding and awareness of the nuclear cycle. This serves to strengthen ties with area school districts, because the power plant is now looked upon as an educational resource

  5. A universal optimization strategy for ant colony optimization algorithms based on the Physarum-inspired mathematical model

    International Nuclear Information System (INIS)

    Zhang, Zili; Gao, Chao; Liu, Yuxin; Qian, Tao

    2014-01-01

    Ant colony optimization (ACO) algorithms often fall into the local optimal solution and have lower search efficiency for solving the travelling salesman problem (TSP). According to these shortcomings, this paper proposes a universal optimization strategy for updating the pheromone matrix in the ACO algorithms. The new optimization strategy takes advantages of the unique feature of critical paths reserved in the process of evolving adaptive networks of the Physarum-inspired mathematical model (PMM). The optimized algorithms, denoted as PMACO algorithms, can enhance the amount of pheromone in the critical paths and promote the exploitation of the optimal solution. Experimental results in synthetic and real networks show that the PMACO algorithms are more efficient and robust than the traditional ACO algorithms, which are adaptable to solve the TSP with single or multiple objectives. Meanwhile, we further analyse the influence of parameters on the performance of the PMACO algorithms. Based on these analyses, the best values of these parameters are worked out for the TSP. (paper)

  6. Tour leaders with detailed knowledge of travel-related diseases play a key role in disease prevention.

    Science.gov (United States)

    Hsu, Shu-Hua; Huang, Hsien-Liang; Lu, Chia-Wen; Cheng, Shao-Yi; Lee, Long-Teng; Chiu, Tai-Yuan; Huang, Kuo-Chin

    2018-02-01

    In Taiwan, group tours are a popular mode of international travel; hence, group tour leaders must ensure traveler safety and health. This study identified factors influencing tour leaders' willingness to recommend pretravel medical consultation and vaccination.A cross-sectional questionnaire survey was administered to tour leaders from January 2011 to December 2012. Multivariate logistic regression analyses were performed to estimate the odds ratios of having a positive attitude and willingness based on different knowledge scores of the tour leaders after adjustments for age, sex, education level, and seniority.Tour leaders with a more detailed knowledge of both travel-related infectious and noninfectious diseases demonstrated a higher willingness to receive vaccination. They believed that consultation at travel clinics before travel can improve travelers' health (P educating tour leaders' knowledge about travel-related diseases to improve health care for travelers.

  7. On Tour with the Prince: Monarchy, Imperial Politics and Publicity in the Prince of Wales's Dominion Tours 1919-20.

    Science.gov (United States)

    Mort, Frank

    2018-03-01

    The stage managers of ritual and the media transformed the British monarchy in the late-nineteenth and early-twentieth century, consolidating its image as splendid and popular and also as more accessible and quasi-democratic. Historians have emphasized that these processes of modernization largely began in Britain. This article locates the origins of democratized royal ritual in the white dominions, especially after 1918. Canada, Australia and New Zealand were political and cultural laboratories where royal advisors and British and dominion politicians launched experiments in the practice of progressive empire and innovatory styles of informal ceremonial, which had a long-term impact on imperial and later Commonwealth relations. Focusing on the Prince of Wales's early dominion tours, the article argues that though royal diplomacy followed earlier itineraries in efforts to consolidate the racialized British world, it also threw up new and unintended consequences. These registered the rapidly changing international order after the collapse of the European monarchies, together with the demands of the prince's own modernist personality. Faced with republican and socialist opposition in Australia and Canada, the touring prince was drawn into competing forms of nationalism, as dominion politicians and journalists embraced him as representing domestic aspirations for self-government and cultural recognition. It is argued that modern royalty personified by the Prince of Wales problematizes the history of twentieth-century public reputations defined by the culture of celebrity. The British monarchy was forced to confront both the constitutional claims of empire and the politics of dominion nationalism, as well as the pressures of international publicity.

  8. Personalized Location-Based Recommendation Services for Tour Planning in Mobile Tourism Applications

    Science.gov (United States)

    Yu, Chien-Chih; Chang, Hsiao-Ping

    Travel and tour planning is a process of searching, selecting, grouping and sequencing destination related products and services including attractions, accommodations, restaurants, and activities. Personalized recommendation services aim at suggesting products and services to meet users’ preferences and needs, while location-based services focus on providing information based on users’ current positions. Due to the fast growing of user needs in the mobile tourism domain, how to provide personalized location-based tour recommendation services becomes a critical research and practical issue. The objective of this paper is to propose a system architecture and design methods for facilitating the delivery of location-based recommendation services to support personalized tour planning. Based on tourists’ current location and time, as well as personal preferences and needs, various recommendations regarding sightseeing spots, hotels, restaurants, and packaged tour plans can be generated efficiently. An application prototype is also implemented to illustrate and test the system feasibility and effectiveness.

  9. 77 FR 13384 - Additional Guidance on Airfare/Air Tour Price Advertisements; Correction

    Science.gov (United States)

    2012-03-06

    ...The Department published a notice entitled ``Additional Guidance on Airfare/Air Tour Price Advertisements,'' in the Federal Register of February 27, 2012; the notice contained an incorrect address for the Department.

  10. ASSOCIATION RULE ANALYSIS FOR TOUR ROUTE RECOMMENDATION AND APPLICATION TO WCTSNOP

    Directory of Open Access Journals (Sweden)

    H. Fang

    2017-09-01

    Full Text Available The increasing E-tourism systems provide intelligent tour recommendation for tourists. In this sense, recommender system can make personalized suggestions and provide satisfied information associated with their tour cycle. Data mining is a proper tool that extracting potential information from large database for making strategic decisions. In the study, association rule analysis based on FP-growth algorithm is applied to find the association relationship among scenic spots in different cities as tour route recommendation. In order to figure out valuable rules, Kulczynski interestingness measure is adopted and imbalance ratio is computed. The proposed scheme was evaluated on Wangluzhe cultural tourism service network operation platform (WCTSNOP, where it could verify that it is able to quick recommend tour route and to rapidly enhance the recommendation quality.

  11. EFEKTIFITAS METODE GROUP FIELD TOUR MELALUI TEKNIK SIMFONI OTAK DALAM PEMBELAJARAN PENULISAN SASTRA KREATIF

    Directory of Open Access Journals (Sweden)

    Akhmad Fauzan

    2014-03-01

    Full Text Available Group field tour methode by Brain Symphoni Technique Investigate how the advantages of implementation. To get the goal the reseacher used Quasi experiment by giving pre test and post test to two different classes as experiment and control class. In experiment class is given the reatment but control class is not. Based on that fact, the problems as follow (1 Is there any difference between creative student used group field tour methode by Brain Symphony technique and not? (2 Is the usage group field tour methode significant by Brain Symphoni thechnique in Creative Literature Writing. The technique is using Quasi experiment methode. Student used this methode is increasing the competence in short story. It showed by pre test and post test comparasion. In post test the score is significant comparated to control class. The control class is increasing too but it is not as big as experiment class. Key word: group field tour, literature learning.

  12. Association Rule Analysis for Tour Route Recommendation and Application to Wctsnop

    Science.gov (United States)

    Fang, H.; Chen, C.; Lin, J.; Liu, X.; Fang, D.

    2017-09-01

    The increasing E-tourism systems provide intelligent tour recommendation for tourists. In this sense, recommender system can make personalized suggestions and provide satisfied information associated with their tour cycle. Data mining is a proper tool that extracting potential information from large database for making strategic decisions. In the study, association rule analysis based on FP-growth algorithm is applied to find the association relationship among scenic spots in different cities as tour route recommendation. In order to figure out valuable rules, Kulczynski interestingness measure is adopted and imbalance ratio is computed. The proposed scheme was evaluated on Wangluzhe cultural tourism service network operation platform (WCTSNOP), where it could verify that it is able to quick recommend tour route and to rapidly enhance the recommendation quality.

  13. "Moral Realism" and Justness in War in Gregory of Tours'"Historia Francorum".

    Science.gov (United States)

    Reynolds, Burnam W.

    1982-01-01

    Examines how the concept of justness influenced the conduct of wars in the early Middle Ages. The author offers a new interpretation of Gregory of Tours' perspective on war as found in his "Historia Francorum." (AM)

  14. Hawaii Volcanoes National Park Air Tour Management Plan: Planning and NEPA Scoping Document

    Science.gov (United States)

    2004-03-03

    The Federal Aviation Administration (FAA), in cooperation with the National Park Service (NPS), has initiated the development of Air Tour Management Plans (ATMPs) for Haleakala National Park, Hawaii Volcanoes National Park, Puukohola Heiau National H...

  15. Evaluating Bloemfontein’s image as a tourist destination: A tour operator’s perspective

    Directory of Open Access Journals (Sweden)

    AJ Strydom

    2014-07-01

    Full Text Available Tour operators have been identified as vital information sources influencing the images and decision-making processes of tourists. Bloemfontein is situated in Central South Africa.  Tourism marketers believe that the city is an ideal stopover destination for national tour operators  en route to other destinations.  Research was conducted among national tour operators in Johannesburg, Durban and Cape Town to determine their perceptions of Bloemfontein and whether they regard the city as a tourist or stopover destination.  The research indicates that the city is not regarded as a tourist destination, but is seen as an ideal stopover destination which could be included in future tour itineraries.  It is currently excluded because operators are unfamiliar with the tourism offering(s of Bloemfontein due to insufficient marketing by the tourism officials of the city.

  16. A gentlemanly tour on the fringes of Europe: William Hartigan Barrington in Scandinavia and Russia, 1837

    OpenAIRE

    Byrne, Angela

    2013-01-01

    In 1837, 22-year-old William Hartigan Barrington (1815–72) made a five-month tour of northern Europe. His detailed diaries describe his encounters with the people and cultures of Scandinavia and Russia, and his interest in a range of topics considered suitable for an educated young gentleman, including systems of government, the arts, manufacturing and commerce, infrastructure, and the poor and poor relief. His tours were expected to provide certain educational and socio-cultural benefits, wh...

  17. Business Ethics of Tour Operators – The Case Study of TUI

    OpenAIRE

    Marija Šuleić; Aleksandra Dragin; Vanja Dragićević

    2014-01-01

    A large number of participants in tourism, both in offer and in demand, has conditioned the need for the creation ethical codices based on legislative regulations and moral principles. Among central figures in tourism, there are travel agencies and tour operators, the intermediaries between service providers and service users, in other words, passengers. The tour operators who are engaged in initiating tourism provide the services on foreign markets and tend to adapt their business to the law...

  18. Communicating for Climate Change Adaptation: Lessons from a Case Study with Nature-Based Tour Operators

    Science.gov (United States)

    Timm, K.; Sparrow, E. B.; Pettit, E. C.; Trainor, S. F.; Taylor, K.

    2014-12-01

    Increasing temperatures are projected to have a positive effect on the length of Alaska's tourism season, but the natural attractions that tourism relies on, such as glaciers, wildlife, fish, or other natural resources, may change. In order to continue to derive benefits from these resources, nature-based tour operators may have to adapt to these changes, and communication is an essential, but poorly understood, component of the climate change adaptation process. The goal of this study was to determine how to provide useful climate change information to nature-based tour operators by answering the following questions: 1. What environmental changes do nature-based tour operators perceive? 2. How are nature-based tour operators responding to climate and environmental change? 3. What climate change information do nature-based tour operators need? To answer these questions, twenty-four nature-based tour operators representing 20 different small and medium sized businesses in Juneau, Alaska were interviewed. The results show that many of Juneau's nature-based tour operators are observing, responding to, and in some cases, actively planning for further changes in the environment. The types of responses tended to vary depending on the participants' certainty in climate change and the perceived risks to their organization. Using these two factors, this study proposes a framework to classify climate change responses for the purpose of generating meaningful information and communication processes that promote adaptation and build adaptive capacity. During the course of the study, several other valuable lessons were learned about communicating about adaptation. The results of this study demonstrate that science communication research has an important place in the practice of promoting and fostering climate change adaptation. While the focus of this study was tour operators, the lessons learned may be valuable to other organizations striving to engage unique groups in climate

  19. Wintertime indoor air levels of PM10, PM2.5 and PM1 at public places and their contributions to TSP.

    Science.gov (United States)

    Liu, Yangsheng; Chen, Rui; Shen, Xingxing; Mao, Xiaoling

    2004-04-01

    From 26 October 2002 to 8 March 2003, particulate matter (PM) concentrations (total suspended particles [TSP], PM10, PM2.5 and PM1) were measured at 49 public places representing different environments in the urban area of Beijing. The objectives of this study were (1) to characterize the indoor PM concentrations in public places, (2) to evaluate the potential indoor sources and (3) to investigate the contribution of PM10 to TSP and the contributions of PM2.5 and PM1 to PM10. Additionally, The indoor and outdoor particle concentrations in the same type of indoor environment were employed to investigate the I/O level, and comparison was made between I/O levels in different types of indoor environment. Construction activities and traffic condition were the major outdoor sources to influence the indoor particle levels. The contribution of PM10 to TSP was even up to 68.8%, while the contributions of PM2.5 and PM1 to PM10 were not as much as that of PM10 to TSP.

  20. Evaluation of tunnel seismic prediction (TSP) result using the Japanese highway rock mass classification system for Pahang-Selangor Raw Water Transfer Tunnel

    Science.gov (United States)

    Von, W. C.; Ismail, M. A. M.

    2017-10-01

    The knowing of geological profile ahead of tunnel face is significant to minimize the risk in tunnel excavation work and cost control in preventative measure. Due to mountainous area, site investigation with vertical boring is not recommended to obtain the geological profile for Pahang-Selangor Raw Water Transfer project. Hence, tunnel seismic prediction (TSP) method is adopted to predict the geological profile ahead of tunnel face. In order to evaluate the TSP results, IBM SPSS Statistic 22 is used to run artificial neural network (ANN) analysis to back calculate the predicted Rock Grade Points (JH) from actual Rock Grade Points (JH) using Vp, Vs and Vp/Vs from TSP. The results show good correlation between predicted Rock Grade points and actual Rock Grade Points (JH). In other words, TSP can provide geological profile prediction ahead of tunnel face significantly while allowing continuously TBM excavation works. Identifying weak zones or faults ahead of tunnel face is crucial for preventative measures to be carried out in advance for a safer tunnel excavation works.

  1. An integrated TSP-GA with EOL cost model for selecting the best EOL option

    Directory of Open Access Journals (Sweden)

    Zakri Ghazalli

    2011-10-01

    Full Text Available This paper presents our research works on integrating design for disassembly with cost model for end-of-life (EOL product. This paper has two objectives. The first objective is to optimize disassembly sequence of the EOL product. We integrate a traveling salesman problem approach with genetic algorithm in finding the optimal disassembly sequence for disassembling the EOL product. Based on this optimal sequence, the second objective is to identify the best EOL option. We employ EOL profits and net present value of parts and subassemblies of the EOL product to determine the best EOL option of components and parts of the EOL product. The predicted results showed that the developed cost model has reached a good correspondence with the established methods.

  2. Los Alamos County Fire Department LAFD: TA-55 PF-4 Facility Familiarization Tour, OJT 55260

    Energy Technology Data Exchange (ETDEWEB)

    Rutherford, Victor Stephen [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-07-13

    Los Alamos National Laboratory (LANL) will conduct familiarization tours for Los Alamos County Fire Department (LAFD) personnel at the Plutonium Facility (PF-4) at Technical Area (TA)-55. These familiarization tours are official LANL business; the purpose of these tours is to orient the firefighters to the facility so that they can respond efficiently and quickly to a variety of emergency situations. This orientation includes the ingress and egress of the area and buildings, layout and organization of the facility, evacuation procedures and assembly points, and areas of concern within the various buildings at the facility. LAFD firefighters have the skills and abilities to perform firefighting operations and other emergency response tasks that cannot be provided by other LANL personnel who have the required clearance level. This handout provides details of the information, along with maps and diagrams, to be presented during the familiarization tours. The handout will be distributed to the trainees at the time of the tour. A corresponding checklist will also be used as guidance during the familiarization tours to ensure that all required information is presented to LAFD personnel.

  3. LAFD: TA-55 RLUOB/CUB Facility Familiarization Tour, OJT #55265

    Energy Technology Data Exchange (ETDEWEB)

    Rutherford, Victor Stephen [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-09-14

    Los Alamos National Laboratory (LANL) conducts familiarization tours for personnel of the Los Alamos County Fire Department (LAFD) at the RLUOB/CUB, technical area (TA)-55, 400/440, facility, Radiological Laboratory Utility Office Building (RLUOB)/Central Utility Building (CUB). These familiarization tours are official LANL business; the purpose of these tours is to orient LAFD firefighters to the facility so that they can respond efficiently and quickly to a variety of emergency situations. This orientation includes, among other topics, the ingress and egress of the area and buildings, layout and organization of the facility, evacuation procedures and assembly points, and areas of concern within the various buildings at the facility. LAFD firefighters have the skills and abilities to perform firefighting operations and other emergency response tasks that cannot be provided by other LANL personnel who have the required clearance level. This handout provides details of the information, along with maps and diagrams, to be presented during the familiarization tours. The handout is distributed to the trainees at the time of the tour; a corresponding checklist is also used as guidance during the familiarization tours to ensure that all required information is presented to LAFD personnel.

  4. STRATEGI PEMASARAN PT. ALLIANCE VAST TOURS TERHADAP WISATAWAN PENGGUNA JASA PERJALANAN

    Directory of Open Access Journals (Sweden)

    I Putu Pradipa Artawan

    2017-01-01

    Full Text Available Indonesia especially Bali has a huge potential in the field of tourism. It can be seen from a wide range of beautiful natural scenery, culture, history of the nation, festivals and ceremonies are unique, different kinds of art and crafts, and a number of very attractive place for tourists throughout the year . The study aims is to determine the marketing strategy of the company's tour packages PT. Vast Alliance Tour who can be success to attract tourists to use the services at PT. Vast Alliance Tour. The analysis using SWOT to determine what the is right strategy which can be used to market package of PT. Vast Alliance Tour. This study led to the conclusion that that the marketing strategies undertaken by PT. Vast Alliance Tour in promoting its products through website, brochures, and sales calls. Products offered by PT. Vast Alliance Tour package in the form of packages like rafting, water sports, cruise, spa, and and much more. Strategy undertaken in this study using the SWOT analysis is to combine the strengths and opportunities that can cover the weaknesses and threats that exist in the relevant product market.

  5. On gravity a brief tour of a weighty subject

    CERN Document Server

    Zee, A

    2018-01-01

    Of the four fundamental forces of nature, gravity might be the least understood and yet the one with which we are most intimate. From the months each of us spent suspended in the womb anticipating birth to the moments when we wait for sleep to transport us to other realities, we are always aware of gravity. In On Gravity, physicist A. Zee combines profound depth with incisive accessibility to take us on an original and compelling tour of Einstein's general theory of relativity. Inspired by Einstein's audacious suggestion that spacetime could ripple, Zee begins with the stunning discovery of gravity waves. He goes on to explain how gravity can be understood in comparison to other classical field theories, presents the idea of curved spacetime and the action principle, and explores cutting-edge topics, including black holes and Hawking radiation. Zee travels as far as the theory reaches, leaving us with tantalizing hints of the utterly unknown, from the intransigence of quantum gravity to the mysteries of dark...

  6. 18th Stage of the 2004 Tour de France

    CERN Multimedia

    Relations with the Hosts States Service

    2004-01-01

    Haute-Savoie / Pays de Gex 23 July 2004 On Friday 23 July 2004, the 18th stage of the Tour de France cycle race will be departing from Annemasse (Haute-Savoie) and heading for Lons-le-Saunier (Jura), passing through Archamps, Saint-Julien-en-Genevois, Collonges, Farges, Saint-Jean-de-Gonville, Thoiry, Sergy, Saint-Genis-Pouilly, Chevry, Gex et Mijoux, inter alia (a detailed itinerary with approximate passage times can be found on http://www.letour.fr/2004/us/index.html). This event is likely to cause numerous disruptions to local traffic, as the roads used by the race will be closed to all vehicles except those bearing the official race insignia: 90 minutes before the first rider comes through; up to 15 minutes after the police vehicle bearing the ' fin de course ' sign has driven through. Furthermore, there will be no access to the centre of Saint-Genis-Pouilly from about 12.30 p.m. to 2.30 p.m. As a result, you are strongly advised to take these difficulties into account when making any car journeys ...

  7. A Guided Tour of Mathematical Methods - 2nd Edition

    Science.gov (United States)

    Snieder, Roel

    2004-09-01

    Mathematical methods are essential tools for all physical scientists. This second edition provides a comprehensive tour of the mathematical knowledge and techniques that are needed by students in this area. In contrast to more traditional textbooks, all the material is presented in the form of problems. Within these problems the basic mathematical theory and its physical applications are well integrated. The mathematical insights that the student acquires are therefore driven by their physical insight. Topics that are covered include vector calculus, linear algebra, Fourier analysis, scale analysis, complex integration, Green's functions, normal modes, tensor calculus, and perturbation theory. The second edition contains new chapters on dimensional analysis, variational calculus, and the asymptotic evaluation of integrals. This book can be used by undergraduates, and lower-level graduate students in the physical sciences. It can serve as a stand-alone text, or as a source of problems and examples to complement other textbooks. All the material is presented in the form of problems Mathematical insights are gained by getting the reader to develop answers themselves Many applications of the mathematics are given

  8. Role of IL-21 in HTLV-1 infections with emphasis on HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP).

    Science.gov (United States)

    Rajaei, Taraneh; Farajifard, Hamid; Rafatpanah, Houshang; Bustani, Reza; Valizadeh, Narges; Rajaei, Bahareh; Rezaee, Seyed Abdolrahim

    2017-06-01

    Interleukin-21 (IL-21) enhances the survival and cytotoxic properties of cytotoxic T cells (CTLs) and exhibits essential roles in controlling chronic viral infections. HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic progressive inflammatory disease of the nervous system. The main determinant of disease progression is efficiency of the CTL response to Human T lymphotropic virus types I (HTLV-1). In this study, the expression of host IL-21 and HTLV-I Tax and proviral load (PVL) was evaluated to understand the role and mechanism of IL-21 in HTLV-1 infections and the subsequent development of HAM/TSP. A cross-sectional study was carried out on 20 HAM/TSP patients, 20 asymptomatic HTLV-1 carriers (ACs) and 20 healthy controls (HCs) to evaluate the expression of IL-21 and Tax and PVL in non-activated and phorbol myristate acetate (PMA)-ionomycin-activated peripheral blood mononuclear cells (PBMCs). The mean mRNA expression of IL-21 in the non-activated and activated PBMCs was higher (by 5-13 times) in the HAM/TSP patients than in ACs and HCs (p Tax and PVL was observed in the HAM/TSP subjects than ACs (p Tax gene expression was positively correlated with PVL (R = 0.595, p = 0.000) and IL-21 gene expression (R = 0.395, p = 0.021) in the HTLV-1-infected subjects. In conclusion, the increase in IL-21 mRNA expression may reflect the attempt of infected T cells to induce an appropriate antiviral response, and the decrease in IL-21 protein expression may reflect the inhibition of IL-21 mRNA translation by viral factors in favour of virus evasion and dissemination.

  9. Nucleotide sequence analysis of HTLV-I isolated from cerebrospinal fluid of a patient with TSP/HAM: comparison to other HTLV-I isolates.

    Science.gov (United States)

    Mukhopadhyaya, R; Sadaie, M R

    1993-02-01

    Human T-cell leukemia virus type I (HTLV-I) has been associated with adult T-cell leukemia/lymphoma and the chronic neurologic disorder tropical spastic paraparesis/HTLV-I-associated myelopathy (TSP/HAM). To study the genetic structure of the virus associated with TSP/HAM, we have obtained and sequenced a partial genomic clone from an HTLV-I-positive cell line established from cerebrospinal fluid (CSF) of a Jamaican patient with TSP/HAM. This clone consisted of a 4.3-kb viral sequence containing the 5' long terminal repeat (LTR), gag, and N-terminal portion of the pol gene, with an overall 1.3% sequence variation resulting from mostly nucleotide substitutions, as compared to the prototype HTLV-I ATK-1. The gag and pol regions showed only 1.4% and 1.2% nucleotide variations, respectively. However, the U3 region of the LTR showed the highest sequence variation (3.6%), where several changes appear to be common among certain TSP/HAM isolates. Several of these changes reside within the 21-bp boundaries and the Tax-responsive element. It would be important to determine if the observed changes are sufficient to cause neurologic disorders similar to the murine leukemia virus system or simply reflect the divergent pool of HTLV-I from different geographic locations. At this time, we cannot rule out the possibility that the observed changes have either direct or indirect significance for the HTLV-I pathogenesis in TSP/HAM.

  10. Parallel optimization algorithm for drone inspection in the building industry

    Science.gov (United States)

    Walczyński, Maciej; BoŻejko, Wojciech; Skorupka, Dariusz

    2017-07-01

    In this paper we present an approach for Vehicle Routing Problem with Drones (VRPD) in case of building inspection from the air. In autonomic inspection process there is a need to determine of the optimal route for inspection drone. This is especially important issue because of the very limited flight time of modern multicopters. The method of determining solutions for Traveling Salesman Problem(TSP), described in this paper bases on Parallel Evolutionary Algorithm (ParEA)with cooperative and independent approach for communication between threads. This method described first by Bożejko and Wodecki [1] bases on the observation that if exists some number of elements on certain positions in a number of permutations which are local minima, then those elements will be in the same position in the optimal solution for TSP problem. Numerical experiments were made on BEM computational cluster with using MPI library.

  11. Threshold-Switchable Particles (TSP’s) to Control Internal Hemorrhage

    Science.gov (United States)

    2011-12-01

    Ismagilov and Morrissey groups for threshold testing. TSPs will be formed from porous and solid nanoparticles with a low-size dispersion optimized for...samples by HUVEC (Human Umbilical Vein Endothelial Cells). Ag NP concentration – 10 µg/ml; Kaolin concentration - 10 µg/ml; MCF-26 concentration 100...µg/ml. (Right) Uptake of various samples by HDFs. Ag NP concentration – 20 µg/ml; Kaolin concentration - 20 µg/ml; MCF-26 concentration 100 µg/ml

  12. Concept and development of measurement method of time sensitivity profile (TSP) in X-ray CT. Comparison of non-helical, single-slice helical, and multi-slice helical scans

    International Nuclear Information System (INIS)

    Tsujioka, Katsumi; Ida, Yoshihiro; Ohtsubo, Hironori; Takahashi, Yasukata; Niwa, Masayoshi

    2000-01-01

    We focused on the time element contained in a single CT image, and devised the concept of a time-sensitivity profile (TSP) describing how the time element is translated into an image. We calculated the data collection time range when the helical pitch is changed in non helical scans, single slice helical scans, and multi slice helical scans. We then calculated the time sensitivity profile (TSP) from the weighting applied when the data collection time range is translated into an image. TSP was also measured for each scanning method using our self-made moving phantom. TSPs obtained from the calculation and the experiments were very close. TSP showed interesting characteristics with each scanning method, especially in the case of multi slice helical scanning, in which TSP became shorter as helical pitch increased. We referred to the TSP's FWHM as the effective scanning time. When we conducted multi slice helical scanning at helical pitch 3, the effective scanning time increased to about 24% longer than that of a non helical scan. When we conducted multi slice helical scanning at helical pitch 5 or 6, the effective scanning time was about half that of a non helical scan. The time sensitivity profile (TSP) is a totally new concept that we consider an important element in discussing the time resolution of a CT scanner. The results of this review will provide significant data in determining the scanning parameters when scanning a moving object. (author)

  13. The motor evoked potential in aids and HAM/TSP State of the evidence El potencial evocado motor en SIDA y HAM/PET

    Directory of Open Access Journals (Sweden)

    Fidias E. Leon-Sarmiento

    2009-12-01

    Full Text Available OBJECTIVE: We aimed to better understand the involvement of the corticospinal tract, assessed by non-invasive transcranial stimulation, in order to determine the actual involvement of the motor system in patients with HAM/TSP and AIDS. METHOD: An exhaustive MEDLINE search for the period of 1985 to 2008 for all articles cross-referenced for "HTLV-I, HTLV-II, HTLV-III and HIV, HIV1, HIV2, evoked potential, motor evoked potential, high voltage electrical stimulation, transcranial magnetic stimulation, magnetic stimulation, corticomotor physiology, motor pathways, acquired immunodeficiency syndrome, AIDS, SIDA, tropical spastic paraparesis, HTLV-I-associated myelopathy, HAM, TSP, and HAM/TSP" were selected and analysed. RESULTS: Eighteen papers published in English, Spanish, Portuguese, French and Japanese were identified. Only the central motor conduction time has been analyzed in seropositive patients to human retroviruses. The investigations done on HAM/TSP support the involvement of the pyramidal tract mainly at lower levels, following a centripetal pattern; in AIDS, such an involvement seems to be more prominent at brain levels following a centrifugal pattern. CONCLUSION: The central motor conduction time abnormalities and involvement differences of the corticospinal tract of patients with AIDS and HAM/TSP dissected here would allow to re-orient early neurorehabilitation measures in these retroviruses-associated neurodegenerative disorders. Besides this, more sophisticated and sensitive non-invasive corticospinal stimulation measures that detect early changes in thalamocortical-basal ganglia circuitry will be needed in both clinically established as well as asymptomatic patients at times when the fastest corticospinal fibers remain uninvolved.OBJETIVO: Investigar el compromiso del tracto piramidal, evaluado por estimulación trascranial no invasiva, en pacientes afectados por SIDA y HAM/TSP. MÉTODO: Se realizó una búsqueda en la base de

  14. Berlin: Sustainability and Tour Guides in a Partial Dark Tourism Destination

    Directory of Open Access Journals (Sweden)

    Asaf Leshem

    2013-10-01

    Full Text Available When guiding in Berlin about the Holocaust or about the Cold War, tour guides often hear the phrase: “I didn’t come here for that, but I want to see that as well...” Many of Berlin’s 10 Million visitors per year claim to have an attraction towards both the morbid and the lighter side of the city. Following from that popular sentiment it is argued that Berlin can be defined as a Partial Dark Tourism Destination. As such, it is further argued that Berlin is prone to an increase of socio-economic and socio-cultural negative impacts. The premise of the research is that Berlin’s tour guides function as a link between the residents of the city and the visitors. The thesis, then, is that tour guides play a role and can contribute to development of social, cultural and economic urban tourism sustainability. An analysis of tourism impacts and tourists-residents relations is presented, in which the tour guide plays a role in influencing the visitor’s behaviour. I conclude that tour guides have greater influence on social, cultural and economic behaviour of the tourist than previously considered, and therefore a potential to enhance sustainable tourism development in Berlin. The significance of this research is in the way it points out to the roles Berlin tour guides play in facilitation of sustainable tourism development in the city. Furthermore, the research shows the ways in which tour guides contribute to increasing responsible tourist behaviour.

  15. Exact and heuristic solutions to the Double TSP with Multiple Stacks

    DEFF Research Database (Denmark)

    Petersen, Hanne Løhmann; Archetti, Claudia; Madsen, Oli B.G.

    -pallet, which can be loaded in 3 stacks in a standard 40 foot container. Different exact and heuristic solution approaches to the DTSPMS have been implemented and tested. The exact approaches are based on different mathematical formulations of the problem which are solved using branch-and-cut. One formulation...... instances. The implemented heuristics include tabu search, simulated annealing and large neighbourhood search. Particularly the LNS approach shows promising results. It finds the known optimal solution of smaller instances (15 orders) within 10 seconds in most cases, and in 3 minutes it finds solutions...

  16. EDF feedback on recent EPRI SGOG SG chemical cleanings applications for TSP blockage reduction and heat transfer recover

    International Nuclear Information System (INIS)

    Dijoux, M.; De Bouvier, O.; Mercier, S.; Pages, D.; Bretelle, J.-L.; Leclercq, P.; Mermillod, A.

    2010-01-01

    Between 2007 and 2008, six Steam Generators Chemical Cleanings (SGCC) with the inhibitor free high temperature process were applied on EDF PWR units. The main goal was to reduce the excessive Tube Support Plate blockages observed on several units of the EDF fleet and the consequences on wide range levels and the risk of tube cracks. The heat transfer recovery was the second objective. Despite the correct results obtained, the corrosion impact of the high temperature process on internal metallic surfaces, higher than expected, and the environmental issues led EDF to move to a new cleaning process. The low temperature process developed by EPRI SGOG and applied for many years was selected for the same purpose. Some qualification laboratory tests were performed by Dominion Engineering Inc (DEI) to demonstrate the innocuousness an the efficiency of the process to achieve these goals. The EPRI SGOG process was then applied seven times by Westinghouse on the EDF units Cruas 3, Cruas 2, Belleville 1, Cattenom 1, Cattenom 3, Chinon B3 and Cattenom 4 between 2008 and 2010. All these units operate from the initial start at low AVT pH 25 o C (9,2) in the secondary circuit. Due to copper presence in the deposits to remove, the cleaning sequence 'Copper - Iron - Copper steps' was performed each time. After a short description of the process, including the specific adaptation in France, lessons learned are reported in this paper in the following areas: process monitoring, corrosion, efficiency, liquid and gaseous wastes, chemical pollution during start-up. Based on the 3 first applications in 2008, some modifications of the process were implemented, particularly for the copper step. For the units cleaned, 1100 to 4500 kg of deposits per SG have been removed, including TS sludge lancing. The reduction of TSP blockages was satisfying. The effect on steam pressure improvement and the wide range level is then discussed. The paper concludes on EDF perspectives for soft

  17. Carbon Dioxide Concentrations and Temperatures within Tour Buses under Real-Time Traffic Conditions.

    Science.gov (United States)

    Chiu, Chun-Fu; Chen, Ming-Hung; Chang, Feng-Hsiang

    2015-01-01

    This study monitored the carbon dioxide (CO2) concentrations and temperatures of three 43-seat tour buses with high-passenger capacities in a course of a three-day, two-night school excursion. Results showed that both driver zones and passenger zones of the tour buses achieved maximum CO2 concentrations of more than 3000 ppm, and maximum daily average concentrations of 2510.6 and 2646.9 ppm, respectively. The findings confirmed that the CO2 concentrations detected in the tour buses exceeded the indoor air quality standard of Taiwan Environmental Protection Administration (8 hr-CO2: 1000 ppm) and the air quality guideline of Hong Kong Environmental Protection Department (1 hr-CO2: 2500 ppm for Level 1 for buses). Observations also showed that high-capacity tour bus cabins with air conditioning system operating in recirculation mode are severely lacking in air exchange rate, which may negatively impact transportation safety. Moreover, the passenger zones were able to maintain a temperature of between 20 and 25°C during travel, which effectively suppresses the dispersion of volatile organic compounds. Finally, the authors suggest that in the journey, increasing the ventilation frequency of tour bus cabin, which is very beneficial to maintain the travel safety and enhance the quality of travel.

  18. Decision Factors for Domestic Package Tours – Case Study of a Region in South Africa

    Directory of Open Access Journals (Sweden)

    Nerine Bresler

    2011-04-01

    Full Text Available This article argues that perceived risk is an inhibitor for the emerging domestic market to develop a culture of going on holiday, which is necessary for the sustainable development of tourism in South Africa. Entrenching a culture of travel can be expedited through appropriate package tours in the same way as it stimulated domestic travel in former Eastern European societies. Packaged tours provide convenience, and both psychological and financial security in a single transaction which can be considered a surrogate for the benefit of risk avoidance when visiting friends and relatives. A survey was conducted in the most promising region, namely the province Gauteng, among the potential market to identify the importance of decision factors for domestic packaged tours. The most important perceived decision criteria were cancellation possibility, affordability, and safety whilst on tour and the three least important were radio promotion, train transport and proximity. The results may be used by the National Department of Tourism to promote domestic tourism, as well as by new and small tour operators to improve decision-making and render competition more knowledge-based. It would thus serve the needs of both tourist buyers and tourism sellers and contribute to sustainable development.

  19. Carbon Dioxide Concentrations and Temperatures within Tour Buses under Real-Time Traffic Conditions

    Science.gov (United States)

    Chiu, Chun-Fu; Chen, Ming-Hung; Chang, Feng-Hsiang

    2015-01-01

    This study monitored the carbon dioxide (CO2) concentrations and temperatures of three 43-seat tour buses with high-passenger capacities in a course of a three-day, two-night school excursion. Results showed that both driver zones and passenger zones of the tour buses achieved maximum CO2 concentrations of more than 3000 ppm, and maximum daily average concentrations of 2510.6 and 2646.9 ppm, respectively. The findings confirmed that the CO2 concentrations detected in the tour buses exceeded the indoor air quality standard of Taiwan Environmental Protection Administration (8 hr-CO2: 1000 ppm) and the air quality guideline of Hong Kong Environmental Protection Department (1 hr-CO2: 2500 ppm for Level 1 for buses). Observations also showed that high-capacity tour bus cabins with air conditioning system operating in recirculation mode are severely lacking in air exchange rate, which may negatively impact transportation safety. Moreover, the passenger zones were able to maintain a temperature of between 20 and 25°C during travel, which effectively suppresses the dispersion of volatile organic compounds. Finally, the authors suggest that in the journey, increasing the ventilation frequency of tour bus cabin, which is very beneficial to maintain the travel safety and enhance the quality of travel. PMID:25923722

  20. A F o cus on Far Eastern Tourists – Tour Operator Selection Criteria

    Directory of Open Access Journals (Sweden)

    Ayşe Çelik

    2014-03-01

    Full Text Available Tour operators are becoming more important in the long haul destination market. Identifying tour operator selection criteria is crucial to orientate marketing strategies. The aim of the study was to determine the tour operation selection criteria of a package holiday maker visiting Turkey from the Far East according to the nationality. Data was drawn up and analyzed from tourists who came from three of these countries namely: Japan, South Korea, and China between February and April 2013 in Cappadocia. Quantitative methodology employing One-way ANOVA analysis was used. Deduction was made by analysing the tour operator selection criteria data that nationality was not a meaningful differentiation for a tourist in their assessment of the “Service Quality’” and “Opportunity to interact with other people’” items referred to in the survey questionnaire. Other items from the resulting data gave meaningful differences in cross - cultural behaviour. Results from the study provide important cues for tour operator managers to consider developing different promotional strategy initiatives to engage and attract more Japanese, South Korean, and Chinese tourists to Turkey.

  1. EKSPEKTASI DAN PERSEPSI WISATAWAN TERHADAP KUALITAS PELAYANAN PADA MARINA SRIKANDI TOUR & TRAVEL DI PADANGBAI

    Directory of Open Access Journals (Sweden)

    Made Natha Dwipayana

    2013-12-01

    Full Text Available Differences between expectation and perception of visitor about service quality of a travel agency were the background of this research which is entitled “Visitor’s Perception And Expectation of Service Quality At Marina Srikandi Tour And Travel In Padang Bai. Through this research, a thought to maintain professionalism of travel agency with qualified standards, understand different visitor expectations was a major thing that want to be achieved. Background of problem in this research was divided into two problems, such as (1 what are visitor expectation and perception about service quality at Marina Srikandi Tour and travel? (2 How is the visitor’s satisfaction about service quality which is given by Marina Srikandi Tour and travel? Based on the background of problems above, there were two aims of study in this research, they are: (1 to know visitor expectation and perception about service quality at Marina Srikandi Tour and travel, and (2 to know visitor’s satisfaction about service quality which is given by Marina Srikandi Tour and travel.

  2. FAKTOR FAKTOR YANG MEMPENGARUHI LAYANAN RESERVASI HOTEL DI PT. BALI MEGAH WISATA TOUR AND TRAVEL

    Directory of Open Access Journals (Sweden)

    Si Gede Ngurah Bramantya Agustiano

    2016-07-01

    Full Text Available This study aims to determine the factors that influence hotel reservation service at Bali Megah Wisata Tour and Travel and a contributing factor dominant in hotel reservation service at Bali Megah Wisata Tour and Travel. The respondents in this study use purposive sampling technique in which the criteria are tourists who have made hotel reservation at Bali Megah Wisata Tour and Travel, with the total sample of 190 respondents. Questionnaires were used to collect data have been tested for validity and reliability. The data analysis which is used to answer the hypothesis of this study is factor analysis. The results of factor analysis showed that 5 factors affecting hotel reservation service at Bali Megah Wisata Tour and Travel are structur and ease of use factor with eigen value 6,492, reputation and security factor with eigen value 2,671, usefulness factor with eigen value 2,497, information content factor with eigen value 1,889 and responsiveness and personalization factor with eigen value 1,059. Structure and ease of use factor is a contributing factor dominant in hotel reservation service at Bali Megah Wisata Tour and Travel.

  3. Spatial and temporal variations of chemicals in the TSP aerosols simultaneously collected at three islands in Okinawa, Japan

    Science.gov (United States)

    Arakaki, Takemitsu; Azechi, Sotaro; Somada, Yuka; Ijyu, Moriaki; Nakaema, Fumiya; Hitomi, Yuya; Handa, Daishi; Oshiro, Yoshito; Miyagi, Youichi; Tsuhako, Ai; Murayama, Hitomi; Higaonna, Yumi; Tanahara, Akira; Itoh, Akihide; Fukushima, Soko; Higashi, Kazuaki; Henza, Yui; Nishikawa, Rin; Shinjo, Hibiki; Wang, Hongyan

    2014-11-01

    East Asia's rapid economic growth has led to concerns about the emission of air pollutants. We collected total suspended particle (TSP) aerosol samples simultaneously at three islands in Okinawa, Japan, which are downwind of East Asia, during the Asian dust season, to examine the spatial and temporal variations and chemical transformations of major chemicals in the aerosols. Weekly samples were collected from July 2008 to June 2010, and the concentrations of water-soluble cations, anions, and organic carbon (WSOC) were determined (n = 303). Spatial distribution analysis showed that monthly mean concentrations of non-sea-salt (nss)-SO42- in the spring (Asian dust season) decreased with increasing distance from Asia, while the trend for NO3- was less evident, suggesting that chemical transformation affected the long-range transport of certain chemicals. Temporal variation analysis showed that concentrations of nss-SO42-, NO3-, and WSOC during the spring were about 2.0, 2.4, and 1.8 times those in the summer (cleaner air mass from the Pacific Ocean), respectively. This study demonstrated that air pollutants were transported from the Asian continent to the Okinawa islands and affected the air quality in the region. There may also be impacts on ecosystems, because increased concentrations of particulate NO3- could increase nutrient levels around the Okinawa islands.

  4. STRATEGI PEMASARAN PAKET WISATA PILGRIM PT. DONGAN SAHUTA TOUR AND TRAVEL DI BALI

    Directory of Open Access Journals (Sweden)

    Paradita Putri Amelia

    2017-04-01

    Full Text Available This study aimed to determine the marketing activities of pilgrim package tour that have been performed by PT. Dongan Sahuta Tour and Travel, develop strategies and also marketing programs that can be implemented by the company. Data collection by observation, interviews, questionnaires and literature study. The sampling technique used purposive sampling. Data were analyzed using qualitative descriptive analysis, analysis of the Likert scale and SWOT analysis approach. The results obtained there are four teen indicators of strengths, weaknesses of tree indicators, four indicators of opportunities and four indicators threats. Marketing strategies that can be implemented by the firm such as 1create and develop a quality product, 2provide rebates to customers who have used the services of PT. Dongan Sahuta Tour and Travel several times.The advice given are more active in the promotion by giving rebates, conduct marketing activities as E-commers, expand cooperation with business trips or individuals.

  5. Modifying Memory: Selectively Enhancing and Updating Personal Memories for a Museum Tour by Reactivating Them

    Science.gov (United States)

    St. Jacques, Peggy L.; Schacter, Daniel L.

    2013-01-01

    Memory can be modified when reactivated, but little is known about how the properties and extent of reactivation can selectively affect subsequent memory. We developed a novel museum paradigm to directly investigate reactivation-induced plasticity for personal memories. Participants reactivated memories triggered by photos taken from a camera they wore during a museum tour and made relatedness judgments on novel photos taken from a different tour of the same museum. Subsequent recognition memory for events at the museum was better for memories that were highly reactivated (i.e., the retrieval cues during reactivation matched the encoding experience) than for memories that were reactivated at a lower level (i.e., the retrieval cues during reactivation mismatched the encoding experience), but reactivation also increased false recognition of photographs depicting stops that were not experienced during the museum tour. Reactivation thus enables memories to be selectively enhanced and distorted via updating, thereby supporting the dynamic and flexible nature of memory. PMID:23406611

  6. Corrosion and solubility in a TSP-buffered chemical environment following a loss of coolant accident: Part 4 – Integrated chemical effects testing

    Energy Technology Data Exchange (ETDEWEB)

    Ali, Amir; LaBrier, Daniel [Department of Nuclear Engineering, University of New Mexico (United States); Blandford, Edward, E-mail: edb@unm.edu [Department of Nuclear Engineering, University of New Mexico (United States); Howe, Kerry [Department of Civil Engineering, University of New Mexico (United States)

    2016-04-15

    Highlights: • Integrated test explored the material release of a postulated large break LOCA. • Aluminum concentration was very low (<0.1 mg/L) throughout the test duration. • Zinc concentration was low (<1 mg/L) in TSP-buffered system. • Calcium release showed two distinguished release zones: prompt and meta-stable. • Copper and iron has no distinguishable concentration up to first 24 h of testing. - Abstract: This paper presents the results of an integrated chemical effects experiment executed under conditions representative of the containment pool following a postulated loss of coolant accident (LOCA) at the Vogtle nuclear power plant, operated by the Southern Nuclear Operating Company (SNOC). This test was conducted for closure of a series of bench scale experiments conducted to investigate the effect of the presence of trisodium phosphate (TSP) on the corrosion and release of aluminum (Howe et al., 2015) and zinc (Pease et al., 2015) from metallic surfaces, and calcium from NUKON fiberglass insulation (Olson et al., 2015) . The integrated test was performed in the Corrosion/Chemical Head Loss Experimental (CHLE) facility with representative amounts of zinc, aluminum, carbon steel, copper, NUKON fiberglass, and latent debris. The test was conducted using borated TSP-buffered solution under a post-LOCA prototypical temperature profile lasting for 30 days. The results presented in this article demonstrate trends for zinc, aluminum, and calcium release that are consistent with separate bench scale testing and previous integrated tests under TSP conditions. The release rate and maximum concentrations of the released materials were slightly different than the separate effect testing as a result of different experimental conditions (temperature, surface area-to-water volume ratio) and/or the presence of other metals and chemicals in the integrated test. Samples of metal coupons and fiberglass were selected for analysis using Scanning Electron Microscopy

  7. Pengaruh Pemberian Urea, Tsp, Kcl Dan Pupuk Organik Cair (Poc) Kulit Pisang Terhadap Pertumbuhan Dan Produksi Tanaman Cabai Merah Keriting (Capsicum Annum L.)

    OpenAIRE

    adrian, Edo; Yetti, Husna

    2017-01-01

    This research to determine the interaction of inorganic fertilizer (Urea, TSP, KCl)and banana peelliquid organic fertilizer (POC) to find the best results on the growth and yield of red pepper (Capsicum annuum L.).This study was conducted for four months (March-June, 2016), the Experimental Station, Faculty of Agriculture, University of Riau Pekanbaru,using a completely randomized design (CRD) factorial,consists of two factors and three replications.The results were analyzed by analysis of va...

  8. Corrosion and solubility in a TSP-buffered chemical environment following a loss of coolant accident: Part 4 – Integrated chemical effects testing

    International Nuclear Information System (INIS)

    Ali, Amir; LaBrier, Daniel; Blandford, Edward; Howe, Kerry

    2016-01-01

    Highlights: • Integrated test explored the material release of a postulated large break LOCA. • Aluminum concentration was very low (<0.1 mg/L) throughout the test duration. • Zinc concentration was low (<1 mg/L) in TSP-buffered system. • Calcium release showed two distinguished release zones: prompt and meta-stable. • Copper and iron has no distinguishable concentration up to first 24 h of testing. - Abstract: This paper presents the results of an integrated chemical effects experiment executed under conditions representative of the containment pool following a postulated loss of coolant accident (LOCA) at the Vogtle nuclear power plant, operated by the Southern Nuclear Operating Company (SNOC). This test was conducted for closure of a series of bench scale experiments conducted to investigate the effect of the presence of trisodium phosphate (TSP) on the corrosion and release of aluminum (Howe et al., 2015) and zinc (Pease et al., 2015) from metallic surfaces, and calcium from NUKON fiberglass insulation (Olson et al., 2015) . The integrated test was performed in the Corrosion/Chemical Head Loss Experimental (CHLE) facility with representative amounts of zinc, aluminum, carbon steel, copper, NUKON fiberglass, and latent debris. The test was conducted using borated TSP-buffered solution under a post-LOCA prototypical temperature profile lasting for 30 days. The results presented in this article demonstrate trends for zinc, aluminum, and calcium release that are consistent with separate bench scale testing and previous integrated tests under TSP conditions. The release rate and maximum concentrations of the released materials were slightly different than the separate effect testing as a result of different experimental conditions (temperature, surface area-to-water volume ratio) and/or the presence of other metals and chemicals in the integrated test. Samples of metal coupons and fiberglass were selected for analysis using Scanning Electron Microscopy

  9. Sabiedriskās ēdināšanas uzņēmuma konkurētspējas analīze

    OpenAIRE

    Beinaroviča, Kristīne

    2011-01-01

    Bakalaura darbs „Sabiedriskās ēdināšanas uzņēmuma konkurētspējas analīze”. Darba mērķis ir izpētīt SIA „G & K” restorāna „Zilā govs” konkurētspēju un izstrādāt priekšlikumus tās uzlabošanai. Bakalaura darba pirmajā nodaļā pētīti konkurences un konkurētspējas teorētiskie aspekti, otrajā nodaļā raksturota nozare, kurā uzņēmums darbojas, valsts ekonomiskās lejupslīdes kontekstā, veikta nozares vides analīze, izmantojot M.E.Portera 5 spēku modeli. Trešajā nodaļā raksturota uzņēmuma vēsturiskā ...

  10. Cēsu alus konkurētspēja un to ietekmējošie faktori Latvijas tirgū.

    OpenAIRE

    Baltroka, Krista

    2014-01-01

    Bakalaura darba tēma „Cēsu alus konkurētspēja un to ietekmējošie faktori Latvijas tirgū”. Konkurence ir viens no svarīgākajiem nosacījumiem uzņēmuma pilnveidošanās procesā, stratēģijas izstrādē. Latvijas tirgū, dzērienu nozarē ir liela konkurence, piedāvāto produktu klāsts ir ļoti plašs. Bakalaura darba mērķis ir izpētīt akciju sabiedrības „Cēsu alus” konkurētspēju ietekmējošos faktorus Latvijas tirgū, kā arī izstrādāt priekšlikumus konkurētspējas paaugstināšanai. Kvantitatīvās analīze...

  11. Chemical mass balance source apportionment of PM10 and TSP in residential and industrial sites of an urban region of Kolkata, India.

    Science.gov (United States)

    Gupta, A K; Karar, Kakoli; Srivastava, Anjali

    2007-04-02

    Daily average PM(10) (particulate matter which passes through a size selective impactor inlet with a 50% efficiency cut-off at 10 microm aerodynamic diameter), TSP (total suspended particulate matter) and their chemical species mass concentrations were measured at residential and industrial sites of an urban region of Kolkata during November 2003-November 2004. Source apportionment using chemical mass balance model revealed that the most dominant source throughout the study period at residential site was coal combustion (42%), while vehicular emission (47%) dominates at industrial site to PM(10). Paved road, field burning and wood combustion contributed 21%, 7% and 1% at residential site, while coal combustion, metal industry and soil dust contributed 34%, 1% and 1% at industrial site, respectively, to PM(10) during the study period. The contributors to TSP included coal combustion (37%), soil dust (19%), road dust (17%) and diesel combustion (15%) at residential site, while soil dust (36%), coal combustion (17%), solid waste (17%), road dust (16%) and tyre wear (7%) at industrial site. Significant seasonal variations of the particulate matters have been observed during the study period. In the monitoring sites total carbon, organic carbon and iron were found to be the marker species of road dust, while organic carbon, total carbon, chloride and sulfate have been observed as the marker species of soil dust in TSP.

  12. The application of ant colony optimization in the solution of 3D traveling salesman problem on a sphere

    Directory of Open Access Journals (Sweden)

    Hüseyin Eldem

    2017-08-01

    Full Text Available Traveling Salesman Problem (TSP is a problem in combinatorial optimization that should be solved by a salesperson who has to travel all cities at the minimum cost (minimum route and return to the starting city (node. Todays, to resolve the minimum cost of this problem, many optimization algorithms have been used. The major ones are these metaheuristic algorithms. In this study, one of the metaheuristic methods, Ant Colony Optimization (ACO method (Max-Min Ant System – MMAS, was used to solve the Non-Euclidean TSP, which consisted of sets of different count points coincidentally located on the surface of a sphere. In this study seven point sets were used which have different point count. The performance of the MMAS method solving Non-Euclidean TSP problem was demonstrated by different experiments. Also, the results produced by ACO are compared with Discrete Cuckoo Search Algorithm (DCS and Genetic Algorithm (GA that are in the literature. The experiments for TSP on a sphere, show that ACO’s average results were better than the GA’s average results and also best results of ACO successful than the DCS.

  13. A branch-and-cut algorithm for the capacitated profitable tour problem

    DEFF Research Database (Denmark)

    Jepsen, Mads Kehlet; Petersen, Bjørn; Spoorendonk, Simon

    2014-01-01

    This paper considers the Capacitated Profitable Tour Problem (CPTP) which is a special case of the Elementary Shortest Path Problem with Resource Constraints (ESPPRC). The CPTP belongs to the group of problems known as traveling salesman problems with profits. In CPTP each customer is associated...... with a profit and a demand and the objective is to find a capacitated tour (rooted in a depot node) that minimizes the total travel distance minus the profit of the visited customers. The CPTP can be recognized as the sub-problem in many column generation applications, where it is traditionally solved through...

  14. The Experiential Learning Impact of International and Domestic Study Tours: Class Excursions That Are More than Field Trips

    Science.gov (United States)

    Gomez-Lanier, Lilia

    2017-01-01

    Experiential education programs, such as international and domestic study tours, bridge the limitations of formal learning classroom by allowing students to experience reality in a new learning dimension. This mixed-methods study explores experiential learning during a domestic interior design study tour to New York City and an international…

  15. Deaf-Accessibility for Spoonies: Lessons from Touring "Eve and Mary Are Having Coffee" While Chronically Ill

    Science.gov (United States)

    Barokka (Okka), Khairani

    2017-01-01

    This article presents lessons from touring a show on pain with limited resources and in chronic pain. In 2014, I toured solo deaf-accessible poetry/art show "Eve and Mary Are Having Coffee" in various forms in the UK, Austria, and India. As an Indonesian woman with then-extreme chronic pain and fatigue, herein are lessons learned from…

  16. Grocery Store (or Supermarket) Tours as an Effective Nutrition Education Medium: A Systematic Review.

    Science.gov (United States)

    Nikolaus, Cassandra J; Muzaffar, Henna; Nickols-Richardson, Sharon M

    2016-09-01

    To evaluate evidence regarding grocery store tours as an effective nutrition education medium for improving nutrition knowledge and food-related behaviors. A systematic literature review of studies published from 1984 to 2015 concerning grocery store (or supermarket) tours and impact on nutrition knowledge and behaviors. Three investigators independently reviewed articles, extracted details, and assessed the quality of each study. Of 307 citations identified, 8 were reviewed and 6 were of neutral quality. Increases in nutrition knowledge were reported in 4 studies, as evaluated by investigator-designed quizzes, with short intervals between tours and assessments. Six programs assessed behavior change using subjective reports or objective purchasing behavior measures; 2 studies did not perform statistical analyses. The 6 studies that reported positive health-related outcomes had varying topics, tour lengths, and target audiences. Grocery store tours are increasingly used as an avenue for nutrition education to improve knowledge and/or alter food selection behaviors and may result in positive outcomes, but it is unknown whether these outcomes persist for longer than 3 months after the tour and whether there are common attributes of effective grocery store tours. More rigorous studies with uniform methodology in study design and outcome measures are needed to confirm the effectiveness of supermarket tours. Copyright © 2016 Society for Nutrition Education and Behavior. Published by Elsevier Inc. All rights reserved.

  17. "Pushing the Boundaries": Participant Motivation and Self-Reported Benefits of Short-Term International Study Tours

    Science.gov (United States)

    Bretag, Tracey; van der Veen, Robert

    2017-01-01

    Short-term overseas study tours serve as a means of developing students' global competencies. The authors conducted pre-departure and post-return focus groups with three groups of students at an Australian university who had participated in short-term study tours to Asia to explore their motivations for participating and their self-reported…

  18. Competitive game theoretic optimal routing in optical networks

    Science.gov (United States)

    Yassine, Abdulsalam; Kabranov, Ognian; Makrakis, Dimitrios

    2002-09-01

    Optical transport service providers need control and optimization strategies for wavelength management, network provisioning, restoration and protection, allowing them to define and deploy new services and maintain competitiveness. In this paper, we investigate a game theory based model for wavelength and flow assignment in multi wavelength optical networks, consisting of several backbone long-haul optical network transport service providers (TSPs) who are offering their services -in terms of bandwidth- to Internet service providers (ISPs). The ISPs act as brokers or agents between the TSP and end user. The agent (ISP) buys services (bandwidth) from the TSP. The TSPs compete among themselves to sell their services and maintain profitability. We present a case study, demonstrating the impact of different bandwidth broker demands on the supplier's profit and the price paid by the network broker.

  19. A NEW HEURISTIC ALGORITHM FOR MULTIPLE TRAVELING SALESMAN PROBLEM

    Directory of Open Access Journals (Sweden)

    F. NURIYEVA

    2017-06-01

    Full Text Available The Multiple Traveling Salesman Problem (mTSP is a combinatorial optimization problem in NP-hard class. The mTSP aims to acquire the minimum cost for traveling a given set of cities by assigning each of them to a different salesman in order to create m number of tours. This paper presents a new heuristic algorithm based on the shortest path algorithm to find a solution for the mTSP. The proposed method has been programmed in C language and its performance analysis has been carried out on the library instances. The computational results show the efficiency of this method.

  20. Incorporating single detector failure into the ROP detector layout optimization for CANDU reactors

    Energy Technology Data Exchange (ETDEWEB)

    Kastanya, Doddy, E-mail: Doddy.Kastanya@snclavalin.com

    2015-12-15

    Highlights: • ROP TSP value needs to be adjusted when any detector in the system fails. • Single detector failure criterion has been incorporated into the detector layout optimization as a constraint. • Results show that the optimized detector layout is more robust with respect to its vulnerability to a single detector failure. • An early rejection scheme has been introduced to speed-up the optimization process. - Abstract: In CANDU{sup ®} reactors, the regional overpower protection (ROP) systems are designed to protect the reactor against overpower in the fuel which could reduce the safety margin-to-dryout. In the CANDU{sup ®} 600 MW (CANDU 6) design, there are two ROP systems in the core, each of which is connected to a fast-acting shutdown system. Each ROP system consists of a number of fast-responding, self-powered flux detectors suitably distributed throughout the core within vertical and horizontal flux detector assemblies. The placement of these ROP detectors is a challenging discrete optimization problem. In the past few years, two algorithms, DETPLASA and ADORE, have been developed to optimize the detector layout for the ROP systems in CANDU reactors. These algorithms utilize the simulated annealing (SA) technique to optimize the placement of the detectors in the core. The objective of the optimization process is typically either to maximize the TSP value for a given number of detectors in the system or to minimize the number of detectors in the system to obtain a target TSP value. One measure to determine the robustness of the optimized detector layout is to evaluate the maximum decrease (penalty) in TSP value when any single detector in the system fails. The smaller the penalty, the more robust the design is. Therefore, in order to ensure that the optimized detector layout is robust, the single detector failure (SDF) criterion has been incorporated as an additional constraint into the ADORE algorithm. Results from this study indicate that there

  1. "Michael Jackson World Tour:" Maps and Globes--Latitude and Longitude.

    Science.gov (United States)

    Benscoter, Gloria Dee

    1988-01-01

    Presents a mapping activity which helps students understand the purpose of latitude and longitude lines. Gives students an opportunity to use longitude and latitude in a meaningful way by asking them to plan a world concert tour for a rock star. Includes a reproducible activity page. (LS)

  2. Thematic tourism as an important segment in the business of modern tour operators

    Directory of Open Access Journals (Sweden)

    Đurašević Silvana

    2014-01-01

    Full Text Available The aim of this paper is to point out to a growing trend of interests of modern tourists for various forms of thematic tourism, as a response to the tendency of uniformity of consumers' lifestyle, which globalization has brought. Thanks to their central place in the tourism system and their expertise, tour operators play a key role in the creation of new programs, 'tailored' to the taste of modern tourists. For that purpose, a number of theoretical assumptions and examples from practice have been analyzed and the method of understanding cause-and-effect relationships is used, in order to examine the role of tour operators in application of new thematic programs. The need to emphasize the special customers' requirements regarding travel services creates an additional problem to tour operators. It indicates the trend of individual trips, which requires a change in choice of markets and product differentiation. The research findings suggest the conclusion that tour operators need to adapt their business strategies to new market conditions, using advantages of information technology in designing diverse thematic programs, which will enable tourists to perceive other local values and express their individuality looking for authentic experiences.

  3. Reading the Urban Landscape: The Case of a Campus Tour at York University, Toronto, Ontario, Canada

    Science.gov (United States)

    Bardekjian, Adrina; Classens, Michael; Sandberg, L. Anders

    2012-01-01

    This paper presents a campus tour assignment in a first-year undergraduate environmental studies course at York University, Toronto, Canada. As a pedagogical tool, the assignment enables students to interrogate the dominant narratives of a university's immediate physical spaces and to apply broader theoretical and practical concepts to their…

  4. Fifty tours are being planned to mark CERN's 50th anniversary

    CERN Multimedia

    2004-01-01

    On 16 October 2004, CERN will open its doors to the public. The Visits Service is already busy with preparations for this day of special events to mark the fiftieth anniversary and is recruiting volunteers. A date for your diaries! On 16 October 2004, CERN will be holding an Open Day to mark its golden jubilee. The public will be invited to discover 50 years of history through tours of 50 different sites. Over thirty sites for the tours have already been identified, including the experiment halls, the assembly halls for the LHC detectors and magnets as well as the computer centre and the fire station. With a programme offering tours, talks, a play on a scientific theme and a variety of workshops, there will be something for everybody. A number of evening tours will be organised specifically for the inhabitants of Cessy, St Genis, Meyrin and Ferney Voltaire, where the experiment halls for CMS, ALICE, ATLAS and LHCb are respectively located. An area will even be set aside with stimulating games to enterta...

  5. Dietetics and Nutrition Students Response to Grocery Store Tour Training Program

    Science.gov (United States)

    Hilliard, Elizabeth D.; Brunt, Ardith; Froelich, Christa; Borr, Mari

    2018-01-01

    Retail dietetics is a growing field, however, there is very little research available on effective teaching strategies for preparing students to enter this part of the profession. This paper is the second paper to report on the results of produce-focused grocery store tour training program. This paper focuses on the trained students' perception of…

  6. Users' Perspectives on Tour-Guide Training Courses Using 3D Tourist Sites

    Science.gov (United States)

    Chen, Yu-Fen; Mo, Huai-en

    2014-01-01

    Taiwan is currently attempting to develop itself into a twenty-first century tourist hub to take advantage of today's thriving global tourism economy. In the coming years, Taiwan anticipates an urgent demand for tour guides, and there is a clear need for training solutions that can serve a rapidly growing population. Computer-mediated virtual 3D…

  7. How can a tour guide robot’s orientation influence visitors’ orientation and formations?

    NARCIS (Netherlands)

    Karreman, Daphne Eleonora; Ludden, Geke Dina Simone; van Dijk, Elisabeth M.A.G.; Evers, Vanessa

    2015-01-01

    In this paper, we describe a field study with a tour guide robot that guided visitors through a historical site. Our focus was to determine how a robot’s orientation behaviour influenced visitors’ orientation and the formations groups of visitors formed around the robot. During the study a

  8. Legacy of Le Grand Départ Tour de France Utrecht 2015

    NARCIS (Netherlands)

    Dijk, Bake; Smits, Froukje; Hover, Paul; Slender, Hans

    2015-01-01

    Abstract for the Sport Management Australia New Zealand conference in Tasmania in 2015. The aim of the abstract is to describe the research we are carrying out in Utrecht to the legacy of the first two stages of the Tour the France 2015 in the city of Utrecht – The Netherlands.

  9. Video-mediated participation in virtual museum tours for older adults

    NARCIS (Netherlands)

    Kostoska, G.; Vermeeren, A.P.O.S.; Kort, J.; Gullström, C.

    2016-01-01

    This paper introduces a virtual tour, Visit the Louvre, designed specifically to engage older adults in an immersive visit through part of the Louvre by a distant real-life guide. An initial diary study and a creative workshop were conducted to understand the needs and values of older adults and how

  10. A PostgreSQL/PostGIS Implementation for the Sightseeing Tour Planning Problem

    Directory of Open Access Journals (Sweden)

    Ardiansyah .

    2013-04-01

    Full Text Available This article discusses a procedure for finding the best multi stops route for sightseeing tour through a road network. The procedure involves building a database containing nodes and road network in PostgreSQL, calculating the shortest distance between a pair of nodes using pgDijkstra module, and solving the tour problem using a function written in PL/pgSQL. The function was developed based on the Nearest Insertion Algorithm for solving the Travelling Salesman Problem. The algorithm inserts a sightseeing attraction (node at the best position in the existing route, which is between a pair of nodes that yields the minimum difference between the total tour time before and after the new node was inserted. The test result shows that the function can solve the problem within acceptable runtime for web application for total destination nodes of 22. It is concluded that the whole procedure was suitable for developing Web GIS application that solve the sightseeing tour planning problem.

  11. James Hutton's Geological Tours of Scotland: Romanticism, Literary Strategies, and the Scientific Quest

    Science.gov (United States)

    Furniss, Tom

    2014-01-01

    Rather than focussing on the relationship between science and literature, this article attempts to read scientific writing as literature. It explores a somewhat neglected element of the story of the emergence of geology in the late eighteenth century--James Hutton's unpublished accounts of the tours of Scotland that he undertook in the years…

  12. Meta-Travel: A Critical Inquiry into a China Study Tour

    Science.gov (United States)

    Riggan, Jennifer; Gwak, Sonya; Lesnick, Joy; Jackson, Kara; Olitsky, Stacey

    2011-01-01

    Short-term study tours are among the fastest growing of study abroad experiences and serve the largest percentage of students choosing to study abroad. Fifty-six percent of students studying abroad go on short-term study trips lasting anywhere from two to eight weeks. These trips have the advantage of being able to provide study travel experiences…

  13. 77 FR 17105 - Commercial Driver's License (CDL) Standards; Rotel North American Tours, LLC; Application for...

    Science.gov (United States)

    2012-03-23

    ... DEPARTMENT OF TRANSPORTATION Federal Motor Carrier Safety Administration [Docket No. FMCSA-2008... Renewal of Exemption; Correction AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION..., Rotel Tours, Das Rollende Hotel, through Georg Hoeltl GmBh & Co.Kg, Tittling, or George Hoeltl GmbH...

  14. Campus Eco Tours: An Integrative & Interactive Field Project for Undergraduate Biology Students

    Science.gov (United States)

    Boes, Katie E.

    2013-01-01

    Outdoor areas within or near college campuses offer an opportunity for biology students to observe the natural world and apply concepts from class. Here, I describe an engaging and integrative project where undergraduate non-major biology students work in teams to develop and present professional "eco tours." This project takes place over multiple…

  15. Food Sovereignty Tours: Can “alternative tourism” contribute to food sovereignty?

    NARCIS (Netherlands)

    K. Brimm; T. Kerssen; Z.W. Brent (Zoe)

    2014-01-01

    markdownabstract__Abstract__ When Food First founded its educational travel program Food Sovereignty Tours in 2010, it had already organized dozens of trips to destinations like Cuba and Kerala, India—places that had carried out radical reforms to greatly improve literacy rates, access to

  16. Debate: The Two Faces of African Feminism | Touré | CODESRIA ...

    African Journals Online (AJOL)

    Debate: The Two Faces of African Feminism. Abibatou Touré, Mamadou Cellou Barry, Pounthioun Diallo. Abstract. No Abstract Available CODESRIA Bulletin No 1 2003: 2-3. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms ...

  17. Utilising excess minibus-taxi capacity for South African townships tours

    NARCIS (Netherlands)

    Rietjens, S.J.H.; Makoriwa, Collins; de Boer, S.J.

    2006-01-01

    This paper proposes an option for the utilisation of excess off-peak capacity of minibus-taxis in South Africa for township tours. The minibus-taxi system typically faces steep peak loads during rush hours with excess vehicle and person capacity available during off-hours. The advantages of the

  18. Ecuador en las páginas de "Le tour du monde"

    NARCIS (Netherlands)

    Gómez Rendón, J.

    2012-01-01

    This is the first and only fully illustrated compilation of articles of the now legendary journal Le Tour du Monde. The book contains all the articles related to Ecuador from 1830 to 1911 and so is a landmark in the nineteenth-century and early twentieth-century travel literature.

  19. Constructing a Social Justice Tour: Pedagogy, Race, and Student Learning through Geography

    Science.gov (United States)

    Barnd, Natchee

    2016-01-01

    This article describes a high-impact learning project that combines geography, history, and ethnic studies. It describes the construction of the course, student outcomes, and the final and publicly presented collaborative project: the Social Justice Tour of Corvallis. Based on work in a small largely white town, this project presents a…

  20. 76 FR 17471 - Air Tour Management Plan Environmental Assessment for Mount Rainier National Park, WA; Public...

    Science.gov (United States)

    2011-03-29

    ... draft alternatives in the development of an Air Tour Management Plan (ATMP) for the Mount Rainier... Environmental Assessment (EA), an ATMP, and associated rulemaking actions which comply with the National...: http://parkplanning.nps.gov/MORA_ATMP or sent to the mailing addresses listed in the ``FOR FURTHER...

  1. A hybrid metaheuristic algorithm for the multi-depot covering tour vehicle routing problem

    NARCIS (Netherlands)

    Allahyari, S.; Salari, M.; Vigo, D.

    2015-01-01

    We propose a generalization of themulti-depot capacitated vehicle routing problem where the assumption of visiting each customer does not hold. In this problem, called the Multi-Depot Covering Tour Vehicle Routing Problem (MDCTVRP), the demand of each customer could be satisfied in two different

  2. Welcome to the Land of the Ideas: The Goethe Institute Fellowship Tour of Germany

    Science.gov (United States)

    Samuelson, Keith

    2007-01-01

    There are many valid reasons for participating in an educators' tour of Germany. It is a nation that has a legacy of literary and political thought that has had a profound impact on the evolution of Western civilization. Germany has offered the world artistic and scientific genius and been the source of devastating war and unprecedented genocide.…

  3. ANALISIS KEBUTUHAN TENAGA KERJA RESERVASI TERHADAP PERENCANAAN PENGEMBANGAN SUMBER DAYA MANUSIA PADA CV. CAN TOUR & TRAVEL

    Directory of Open Access Journals (Sweden)

    Maya Christina

    2017-01-01

    Full Text Available Employment remains the fundamental probel faced by many countries including Indonesia. One of the efforts the Government of Indonesia in extending employment opportunities is to develop the tourism sector. Bali is one of the potential tourist destinastions and it needs to be marketed. Cooperation between the Travel Bureau with the provider of the accommodation or hotel is one of the ways the potential market and the most instrumental in the development of the company, namely human resources required or called by labor. CV. CAN Tour and Travel is one of the tourist industry in Bali trip with a number of guest handling that quite a lot. This research aims to know the availability of labor needs resevartion in order CV. CAN Tour and Travel development and also to find out how the workforce qualification is required. Determination technique using the key informant that was labor reservation CV. CAN Tour and Travel, while the base of the informant was CV. CAN Tour and Travel Manager. Data analysis technique used is the analysis of workload and workforce needs analysis. The research results obtained indicate that shortage of time working as many as 210 minutes. So the manpower needed by CV. CAN Tour and Travel is two people with the fact that there is only 1 nowaday. It can be seen from the burden of the work done in a day’s work and the workforce absences. So labor needs on the Reservation Department is supposed to be 3 people, with 2 staff 1 reservations and ticketing staff. It was necessary increase manpower in the Labour Departmen’s Reservation in the reservation and also training to develop the ability to work.

  4. The Effects of Land-Use Patterns on Home-Based Tour Complexity and Total Distances Traveled: A Path Analysis

    Directory of Open Access Journals (Sweden)

    João de Abreu e Silva

    2018-03-01

    Full Text Available This work studies the relationships between the number of complex tours (with one or more intermediate stops and simple home-based tours, total distances traveled by mode, and land-use patterns both at the residence and at the workplace using path analysis. The model includes commuting distance, car ownership and motorcycle ownership, which are intermediate variables in the relationship between land use, tour complexity and distances traveled by mode. The dataset used here was collected in a region comprising four municipalities located in the north of Portugal that are made up of urban areas, their sprawling suburbs, and surrounding rural hinterland. The results confirm the association between complex tours and higher levels of car use. Land-use patterns significantly affect travelled distances by mode either directly and indirectly via the influence of longer-term decisions like vehicle ownership and commuting distance. The results obtained highlight the role of socioeconomic variables in influencing tour complexity; in particular, households with children, household income, and workers with a college degree tend to do more complex tours. Land-use patterns mediate the effects of tour complexity on the kilometers travelled by different modes. Increasing densities in central areas, and particularly the concentration of jobs, have relevant benefits by reducing car kilometers driven.

  5. Receptor modeling of PM2.5, PM10 and TSP in different seasons and long-range transport analysis at a coastal site of Tianjin, China.

    Science.gov (United States)

    Kong, Shaofei; Han, Bin; Bai, Zhipeng; Chen, Li; Shi, Jianwu; Xu, Zhun

    2010-09-15

    Atmospheric particulate matter (PM(2.5), PM(10) and TSP) were sampled synchronously during three monitoring campaigns from June 2007 to February 2008 at a coastal site in TEDA of Tianjin, China. Chemical compositions including 19 elements, 6 water-solubility ions, organic and elemental carbon were determined. principle components analysis (PCA) and chemical mass balance modeling (CMB) were applied to determine the PM sources and their contributions with the assistance of NSS SO(4)(2)(-), the mass ratios of NO(3)(-) to SO(4)(2)(-) and OC to EC. Air mass backward trajectory model was compared with source apportionment results to evaluate the origin of PM. Results showed that NSS SO(4)(2)(-) values for PM(2.5) were 2147.38, 1701.26 and 239.80 ng/m(3) in summer, autumn and winter, reflecting the influence of sources from local emissions. Most of it was below zero in summer for PM(10) indicating the influence of sea salt. The ratios of NO(3)(-) to SO(4)(2)(-) was 0.19 for PM(2.5), 0.18 for PM(10) and 0.19 for TSP in winter indicating high amounts of coal consumed for heating purpose. Higher OC/EC values (mostly larger than 2.5) demonstrated that secondary organic aerosol was abundant at this site. The major sources were construction activities, road dust, vehicle emissions, marine aerosol, metal manufacturing, secondary sulfate aerosols, soil dust, biomass burning, some pharmaceutics industries and fuel-oil combustion according to PCA. Coal combustion, marine aerosol, vehicular emission and soil dust explained 5-31%, 1-13%, 13-44% and 3-46% for PM(2.5), PM(10) and TSP, respectively. Backward trajectory analysis showed air parcels originating from sea accounted for 39% in summer, while in autumn and winter the air parcels were mainly related to continental origin. Copyright 2010 Elsevier B.V. All rights reserved.

  6. TSP Symposium 2012 Proceedings

    Science.gov (United States)

    2012-11-01

    royalty -free government-purpose license to use, duplicate, or disclose the work, in whole or in part and in any manner, and to have or permit others to... Malaysian Journal of Computer Science 18, 2 (December 2005): 11–27. [Pomeroy-Huff 2012] Pomeroy-Huff, M.; Cannon, R.; Chick, T. A.; Mullaney, J

  7. TSP Symposium 2013 Proceedings

    Science.gov (United States)

    2014-01-01

    Innovación con Nuevas Tecnologías en la Docencia de la Ingeniería. IEEE, 2009. [Börstler 2002] Börstler, J., Carrington, D., Hislop, G. W., Lisack, S...Região do Norte), under project reference SI IDT - 21562/2011. The work of M. Raza is funded by FCT (Fundação para a Ciência e a Tecnologia ), under

  8. [The rotationally stable screw-anchor with trochanteric stabilizing plate (RoSA/TSP) : First results in unstable trochanteric femur fractures].

    Science.gov (United States)

    Maier, K-J; Bücking, B; Horst, K; Andruszkow, H; Hildebrand, F; Knobe, M

    2017-12-01

    In unstable trochanteric fractures, the extramedullary rotationally stable screw-anchor (RoSA) combines the benefits of the load and rotational stability of the blade with the advantages of the screw (pull-out resistance, compression capability) in a single load carrier, and was designed to prevent femoral neck shortening by using an additional locked trochanteric stabilizing plate (TSP). The aim of the current prospective cohort study was the clinical evaluation of the RoSA/TSP system regarding the mechanical re-operation rate and the amount of postoperative femoral neck shortening. From September 2011 to January 2014 80 patients with unstable trochanteric fractures underwent internal extramedullary fixation with the RoSA/TSP (Königsee Implantate GmbH, Allendorf, Germany). Due to fracture stability and after induction of compression, additional long locked antitelescoping screws (AT, n = 1-4) were placed reaching the femoral head. Radiological (femoral neck shortening) and clinical re-examination of patients (n = 61) was performed 6-10 weeks and 6-10 months later. In the 61 re-examined patients (76 %) femoral neck shortening was very low with 2 mm 6-10 months after operation. Re-operations occurred in 8 % (n = 6) and in 4 % (n = 3) as prophylactic surgical intervention. Whereas one-third (4 %) of re-operations occurred due to iatrogenic surgical problems from the first operation two-thirds of patients (8 %) had a re-operation due to delay of bone union (3× nonunion, 3 planned removals of AT-screws to improve healing). The in-hospital mortality was 3 % (n = 2). The fixation of unstable trochanteric femur fractures using the RoSA/TSP in a first clinical setting led to a great primary stability, with significant advantages with regard to limited femoral neck shortening. However, the rigidity of the construct with its consequences regarding bone healing can be challenging for the surgeon. Nevertheless, in some cases of revision it could be beneficial

  9. PERANCANGAN VIRTUAL TOUR KAMPUS I UKSW SEBAGAI MEDIA INFORMASI MAHASISWA BARU

    Directory of Open Access Journals (Sweden)

    Rizal Bastian Nur Budi

    2018-02-01

    Full Text Available Abstrak Kampus I Universitas Kristen Satya Wacana (UKSW beralamat di Jalan Diponegoro 52-56 Kota Salatiga, Jawa Tengah. Memiliki luas keseluruhan 93.580 m2  terdiri dari gedung kantor dan gedung perkuliahan. Media informasi sangat penting bagi mahasiswa untuk mengenali lokasi gedung dan wilayah kampus. Berdasarkan penelitian banyak mahasiswa kesulitan menemukan lokasi gedung perkuliahan dan mengenali wilayah kampus pada awal masa perkuliahan. Media informasi yang telah ada berupa peta dua dimensi wilayah kampus hanya menyajikan informasi yang terbatas. Berdasarkan fakta tersebut, pada penelitian ini dirancang virtual tour panorama 360o  sebagai media informasi Kampus I UKSW untuk mempermudah mahasiswa baru dalam mengenali wilayah serta memberikan informasi awal tentang letak gedung secara visual. Metode perancangan yang digunakan adalah mixed method dan strategi linier. Hasil yang dicapai dari penelitian ini berupa virtual tour sebagai media informasi Kampus I UKSW sudah sesuai dengan harapan, dan layak diaplikasikan pada website Universitas.   Kata Kunci : UKSW, Media Informasi, Virtual tour, Panorama 360o, Mahasiswa Baru   Abstract Campus I of Satya Wacana Christian University (SWCU is located at Diponegoro Street 52-56 Salatiga, Central Java. Campus I UKSW has an overall area of 93,580 m2, consisting of office buildings and lecture buildings. Media information is very important for students to recognize the location of buildings and campus areas. Based on the research, many students have difficulty finding the location of the lecture building and recognize the campus area at the beginning of the lecture. The existing media information that is the two-dimensional map of the campus area presents only limited information. Based on these facts, this research designed virtual panoramic 360o   tour  as  a  medium  of  information  for  Campus  I  SWCU  to  facilitate  new  students  in recognizing the area and providing initial

  10. A combination of genetic algorithm and particle swarm optimization method for solving traveling salesman problem

    Directory of Open Access Journals (Sweden)

    Keivan Borna

    2015-12-01

    Full Text Available Traveling salesman problem (TSP is a well-established NP-complete problem and many evolutionary techniques like particle swarm optimization (PSO are used to optimize existing solutions for that. PSO is a method inspired by the social behavior of birds. In PSO, each member will change its position in the search space, according to personal or social experience of the whole society. In this paper, we combine the principles of PSO and crossover operator of genetic algorithm to propose a heuristic algorithm for solving the TSP more efficiently. Finally, some experimental results on our algorithm are applied in some instances in TSPLIB to demonstrate the effectiveness of our methods which also show that our algorithm can achieve better results than other approaches.

  11. (New) NASA Administrator Sean O'Keefe comes to Ames for employee briefing and tour. Here he welcomes

    Science.gov (United States)

    2002-01-01

    (New) NASA Administrator Sean O'Keefe comes to Ames for employee briefing and tour. Here he welcomes JASON kids to NASA while handing out patches and pins. Tom Clausen and Donald James, Ames Education Office in background.

  12. (New) NASA Administrator Sean O'Keefe comes to Ames for employee briefing and tour. Meets with

    Science.gov (United States)

    2002-01-01

    (New) NASA Administrator Sean O'Keefe comes to Ames for employee briefing and tour. Meets with Roberto Cruz, National Hispanic University (left) at Amesto sign the educational MOU between NHU and Ames.

  13. Two-phase framework for optimal multi-target Lambert rendezvous

    OpenAIRE

    Bang, Jun; Ahn, Jaemyung

    2017-01-01

    This paper proposes a two-phase framework to solve an optimal multi-target Lambert rendezvous problem. The first phase solves a series of single-target rendezvous problems for all departure-arrival object pairs to generate the elementary solutions, which provides candidate rendezvous trajectories (elementary solutions). The second phase formulates a variant of traveling salesman problem (TSP) using the elementary solutions prepared in the first phase and determines the best rendezvous sequenc...

  14. CERN hosts Tour du canton de Genève stage

    CERN Multimedia

    Patrice Loïez

    2004-01-01

    CERN hosted the first stage of the 10th Tour du canton de Genève on the evening of Wednesday 26 May. The Tour du canton is an annual race run in four stages over four weeks, and this year started at CERN as part of the Golden Jubilee celebrations. The event attracted over 2000 runners, including over 40 from CERN, as well as a large crowd of onlookers. The 10.5 km route started and finished outside CERN's Main Building, taking in the Swiss countryside, crossing into France and coming back through the tunnel linking the two CERN sites. CERN runners finished in second place in the Enterprise category just 13 seconds behind Rolex S.A., setting up an exciting contest for the remaining stages at Bernex, Meyrin and Jussy.

  15. Characterisation of cyclists’ willingness to pay for green initiatives at Africa’s largest cycle tour

    Directory of Open Access Journals (Sweden)

    Melville Saayman

    2016-08-01

    Full Text Available The Cape Argus Pick n Pay Cycle Tour is a major event on the road cycling calendar. The majority of cyclists travel significant distances and participation produces a substantial carbon footprint. This paper examines participants’ willingness to pay to offset their carbon footprint. The purpose of this paper is to make a contribution to the literature by linking willingness to pay to attitudes towards or beliefs (green views about the initiatives in place, to ensure a greener cycle tour. Factor analysis is used to identify different types of cyclists, based on their green views: those with green money, those who prefer green products and the “re-cyclers”. The results of the regression analysis reveal that socio-demographic variables and the right attitude towards the environment are significant predictors of stated willingness to pay for climate change mitigation.

  16. PENGARUH SELF-EFFICACYDAN MOTIVASI KERJA PADA KEPUASAN KERJA KARYAWAN HAPPY BALI TOUR & TRAVEL DENPASAR

    Directory of Open Access Journals (Sweden)

    Dewi Putu Eka Purnama

    2015-10-01

    Full Text Available The aim of this study is to determine the influence of self-efficacy and work motivation on employee job satisfaction at Happy Bali Tour and Travel. The data was collected by using questionnaire consisting of a number of statements about self-efficacy, motivation and job satisfaction. This study used saturated sample, where the entire population was selected become sample which is consists of 82 employees. Data analysis techniques used in this research was multiple linear regression. The findings show that simultaneously,  self-efficacy  and  work  motivation  has  a  significant  effect  on  job  satisfaction  of employee. Additionally, self-efficacy and work motivation shows a positive impact on job satisfaction of Happy Bali Tour and Travel employee.

  17. PROSEDUR PENANGANAN RESERVASI PAKET WISATA PT. PANORAMA TOUR AND TRAVEL DENPASAR

    Directory of Open Access Journals (Sweden)

    Maria Melani Rosalina Hutabarat

    2017-01-01

    Full Text Available The travel agent plays an important to roles give all information about tourism destination to the world. Travel agents related activities which are conducted such as inbound and outbound tour, travel documents (passport/visa, ticketing, and the problem are how to handle reservation and find out about the solutions related. Quality and quantity data resources were using as primary and secondary data. Interview and documentation were using for data analysis with descriptive analysis technic. The procedure on how to handle package tour reservation such as: receive make a reservation of overseas agents, file the data and solution for fully booked hotel request, changes the reservations and client’s complaint. Based on the reseach, the company should improve the ability of the staff for correspondence with computerized system and more staff at the airport.

  18. Experimental and numerical analysis of the influence of tyres' properties on the straight running stability of a sport-touring motorcycle

    Science.gov (United States)

    Cossalter, Vittore; Doria, Alberto; Formentini, Matteo; Peretto, Martino

    2012-03-01

    The behaviour of a motorcycle on the road is largely governed by tyre properties. This paper presents experimental and numerical analyses dealing with the influence of tyre properties on the stability of weave and wobble in straight running. The final goal is to find optimal sets of tyre properties that improve the stability of a motorcycle. The investigation is based on road tests carried out on a sport-touring motorcycle equipped with sensors. Three sets of tyres are tested at different speeds in the presence of weave and wobble. The analysis of telemetry data highlights significant differences in the trends of frequency and damping of weave and wobble against speed. The experimental analysis is integrated by a parametric numerical analysis. Tyre properties are varied according to the design of experiments method, in order to highlight the single effects on stability of lateral and cornering coefficient of front and rear tyres.

  19. The impact of a simulated grand tour on sleep, mood, and well-being of competitive cyclists.

    Science.gov (United States)

    Lastella, M; Roach, G D; Halson, S L; Martin, D T; West, N P; Sargent, C

    2015-12-01

    Professional cycling is considered one of the most demanding of all endurance sports. The three major professional cycling stages races (i.e. Tour de France, Giro d'Italia and Vuelta a España) require cyclists to compete daily covering between ~150-200 km for three consecutive weeks. Anecdotal evidence indicates that such an event has a significant effect on the sleep, mood, and general well-being of cyclists, particularly during the latter stages of the event. The primary aim of this study was to simulate a grand tour and determine the impact a grand tour has on the sleep, mood, and general well-being of competitive cyclists. Twenty-one male cyclists (M±SD, age 22.2±2.7 years) were examined for 39 days across three phases (i.e. baseline, simulated grand tour, and recovery). Sleep was assessed using sleep diaries and wrist activity monitors. Mood and general well-being were assessed using the Brunel Mood Scale (BRUMS) and Visual Analogue Scales (VAS). The amount and quality of sleep as assessed by the wrist activity monitors declined during the simulated grand tour. In contrast, self-reported sleep quality improved throughout the study. Cyclists' mood and general well-being as indicated by vigour, motivation, physical and mental state declined during the simulated tour. Future investigations should examine sleep, mood and well-being during an actual grand tour. Such data could prove instrumental toward understanding the sleep and psychological changes that occur during a grand tour.

  20. A virtual tour of geological heritage: Valourising geodiversity using Google Earth and QR code

    Science.gov (United States)

    Martínez-Graña, A. M.; Goy, J. L.; Cimarra, C. A.

    2013-12-01

    When making land-use plans, it is necessary to inventory and catalogue the geological heritage and geodiversity of a site to establish an apolitical conservation protection plan to meet the educational and social needs of society. New technologies make it possible to create virtual databases using virtual globes - e.g., Google Earth - and other personal-use geomatics applications (smartphones, tablets, PDAs) for accessing geological heritage information in “real time” for scientific, educational, and cultural purposes via a virtual geological itinerary. Seventeen mapped and georeferenced geosites have been created in Keyhole Markup Language for use in map layers used in geological itinerary stops for different applications. A virtual tour has been developed for Las Quilamas Natural Park, which is located in the Spanish Central System, using geological layers and topographic and digital terrain models that can be overlaid in a 3D model. The Google Earth application was used to import the geosite placemarks. For each geosite, a tab has been developed that shows a description of the geology with photographs and diagrams and that evaluates the scientific, educational, and tourism quality. Augmented reality allows the user to access these georeferenced thematic layers and overlay data, images, and graphics in real time on their mobile devices. These virtual tours can be incorporated into subject guides designed by public. Seven educational and interpretive panels describing some of the geosites were designed and tagged with a QR code that could be printed at each stop or in the printed itinerary. These QR codes can be scanned with the camera found on most mobile devices, and video virtual tours can be viewed on these devices. The virtual tour of the geological heritage can be used to show tourists the geological history of the Las Quilamas Natural Park using new geomatics technologies (virtual globes, augmented reality, and QR codes).

  1. ANALISIS KUALITAS KINERJA PRAMUWISATA TERHADAP KEPUASAN WISATAWAN JEPANG PADA PARADISE BALI TOUR AND TRAVEL DI BADUNG

    Directory of Open Access Journals (Sweden)

    Arya Adi Palguna

    2015-12-01

    Full Text Available The type of data used are qualitative and quantitative data, while-for the data source is the primary and secondary data. Techniques of data collection is conducted through observation, interviews, and questionnaires. The sampling technique used purposive sampling i.e. applied particular consideration determined by the researcher itself. In another words the researchers have their own criteria toward the Japanese tourists who had ever utilized the services of Paradise Bali Tour and Travel. The result of this study shows that tourists are satisfied by the performance of the Japanese tour guides in Paradise Bali Tour and Travel, with an average rate of suitability is 74.39 percent. Being used Cartesian diagram to analyze the indicators to be a top priority and must be done in accordance with expectations of tourists, such as: guides appearance and neatness and another items and must be used by guide when pick-up the guests, providing clear and accurate information about the condition of destination, and efficiency of time and speedy when pick up the tourists. Indicators are considered important and needed to be maintained its performance are the mastering of foreign languages by guides in order to fluent communication, the courtesy of guides when providing services. Indicators considered less important by tourists but its implementation is quite well done, namely responsiveness guides in providing clear and concise information. Indicator that overestimated by tourist but it have done very well, such as the convenience of tourists when receiving services from the guide during the tour taken place.

  2. Digital imaging of autoradiographs from paintings by Georges de La Tour (1593-1652)

    CERN Document Server

    Fischer, C O; Laurenze, C; Schmidt, C; Slusallek, K

    1999-01-01

    The artistic work of the painter Georges de La Tour has been studied very intensively in the last few years, mainly by French and US-American art historians and natural scientists. To support the in-depth analysis of two paintings from the Kimbell Art Museum in Fort Worth, Texas, USA, two similar paintings from the Gemaeldegalerie Berlin have been investigated. The method of neutron activation autoradiography has been applied using imaging plates with digital image processing.

  3. Rupture traumatique du diaphragme au CHU Gabriel Touré de ...

    African Journals Online (AJOL)

    Rupture traumatique du diaphragme au CHU Gabriel Touré de Bamako, Mali. B T Dembélé, A Togo, A Traoré, Y Sidibé, M Konaté, A A Traoré, A Bah, T Koné, I Tounkara, L Kanté, I Diakité, B Karembé, A Koné, M.I Mangane, G Diallo ...

  4. VIRTUAL TOUR ENVIRONMENT OF CUBA’S NATIONAL SCHOOL OF ART

    Directory of Open Access Journals (Sweden)

    R. K. Napolitano

    2017-08-01

    Full Text Available Innovative technologies have enabled new opportunities for collecting, analyzing, and sharing information about cultural heritage sites. Through a combination of two of these technologies, spherical imaging and virtual tour environment, we preliminarily documented one of Cuba’s National Schools of Art, the National Ballet School.The Ballet School is one of the five National Art Schools built in Havana, Cuba after the revolution. Due to changes in the political climate, construction was halted on the schools before completion. The Ballet School in particular was partially completed but never used for the intended purpose. Over the years, the surrounding vegetation and environment have started to overtake the buildings; damages such as missing bricks, corroded rebar, and broken tie bars can be seen. We created a virtual tour through the Ballet School which highlights key satellite classrooms and the main domed performance spaces. Scenes of the virtual tour were captured utilizing the Ricoh Theta S spherical imaging camera and processed with Kolor Panotour virtual environment software. Different forms of data can be included in this environment in order to provide a user with pertinent information. Image galleries, hyperlinks to websites, videos, PDFs, and links to databases can be embedded within the scene and interacted with by a user. By including this information within the virtual tour, a user can better understand how the site was constructed as well as the existing types of damage. The results of this work are recommendations for how a site can be preliminarily documented and information can be initially organized and shared.

  5. VISITOR PERCEPTIONS OF THE ROLE OF TOUR GUIDES IN NATURAL RESOURCE MANAGEMENT AND SUSTAINABLE TOURISM

    OpenAIRE

    Ozlem Koroglu; Ozlem Guzel

    2013-01-01

    Undoubtedly, development of sustainable tourism activities is closely related to the protection of natural resources. Protection of natural resources is an important issue that should be taken seriously by the communities. Natural resource management includes sharing all the necessary responsibility for the purpose of protecting natural resources, ensuring the sustainability and leaving it to the next generation. This paper aims to explore the visitor perceptions of tour guides to contribute ...

  6. Developing International Marketing for a Geopark Packaged Tour for the Hong Kong market

    OpenAIRE

    Chen, Jing; Wong, Hoi Ki

    2012-01-01

    The development of international tourism does not only show in the increasing number of international tourists but also in the diversified and specialized destinations. The thesis commissioner is Rokua Geopark in Oulu, Finland who is cooperating with other Nordic geoparks in developing international marketing of a Nordic geopark tour for Hong Kong market. The objective of the thesis is to find out possible marketing mix operations and also the features of potential customer group for the ...

  7. 2005 Tour de Sol: The Sustainable Energy and Transportation Festival and Competition

    Energy Technology Data Exchange (ETDEWEB)

    Nancy Hazard

    2005-05-07

    This report gives a summary of the 2005Tour de Sol: The Sustainable Energy and Transportation Festival and Competition. It lists our objectives, what we did, and an analysis of how we met our objectives. An 80-page report with a list of verified print, radio and TV media coverage, and copies of selected news clips and web media coverage is available at the NESEA office for review.

  8. Discourse Analysis of the Multi-Voiced Tourist Guide. Discursive Particularities of Guided Tours

    Directory of Open Access Journals (Sweden)

    Elena Dumitrascu

    2016-01-01

    Full Text Available This paper aims to analyze the discursive peculiarities specific to the oral discourse of a tourguide. Our objective is to highlight the specificity and originality of oral discourse used by the tourguide, and for this, we use a pragmatic analysis, because this type of discourse is stronglyinfluenced by a speech communication situation. The essay is based on an oral corpus consisting ofrecordings made in authentic conditions during a guided tour to Meteora monasteries.

  9. AAS "BALTA" konkurētspēja juridisko personu īpašuma produkta apdrošināšanā Latvijā

    OpenAIRE

    Jukštaka, Elīna

    2012-01-01

    Bakalaura darbā tiek pētīta AAS Balta juridisko personu īpašuma apdrošināšanas produkta konkurētspēja starp vadošajiem tirgus līderiem īpašuma apdrošināšanā Latvijas tirgū. Analizējot juridisko personu īpašuma apdrošināšanas noteikumus un finanšu rādītājus ir izteikti secinājumi un priekšlikumi AAS Balta juridisko personu īpašuma apdrošināšanas produkta konkurētspējas paaugstināšanai. Lai sasniegtu izvirzīto mērķi, autors izpētīja Latvijas nedzīvības apdrošināšanas tirgus attīstību un atse...

  10. Defective human T-cell lymphotropic virus type I (HTLV-I) provirus in seronegative tropical spastic paraparesis/HTLV-I-associated myelopathy (TSP/HAM) patients.

    Science.gov (United States)

    Ramirez, E; Fernandez, J; Cartier, L; Villota, C; Rios, M

    2003-02-01

    Infection with human T-cell lymphotropic virus type I (HTLV-I) have been associated with the development of the tropical spastic paraparesis/HTLV-I-associated myelopathy (TSP/HAM). We studied the presence of HTLV-I provirus in peripheral blood mononuclear cells (PBMC) from 72 Chilean patients with progressive spastic paraparesis by polymerase chain reaction: 32 seropositive and 40 seronegative cases. We amplified different genomic regions of HTLV-I using primers of 5' ltr, tax, env/tax, pX, pol and env genes. These genes were detected from all seropositive patients. The seronegative patients were negative with 5' ltr, pol, env, and pX primers. However, amplified product of tax and env/tax genes was detected from 16 and four seronegative patients, respectively. Three of them were positive with both genetic regions. The results of this study show that the complete HTLV-I provirus is found in 100% of seropositive cases. In seronegative cases, clinically very similar of seropositive cases, was found only tax gene in 42.5% (17/40) of patients. These results suggest the presence of a defective HTLV-I provirus in some seronegative patients with progressive spastic paraparesis, and suggest a pathogenic role of this truncate provirus for a group of TSP/HAM.

  11. Exploring the role of social interactions and supports in overcoming accessibility barriers while undertaking health tours in India.

    Science.gov (United States)

    Jana, Arnab; Harata, Noboru; Kiyoshi, Takami; Ohmori, Nobuaki

    2014-01-01

    This article explores the phenomenon of companionship as an adaptation strategy to counter the existing barriers to health care access in developing nations. Companionship is argued to be an outcome of "inter" and "intra" household collaboration to offer diverse supports in addition to altruism. The analysis of the household survey conducted in West Bengal, India, exhibited different patterns of health care tours and the associated dependencies. In addition to support in terms of mobility while traveling and companionship while waiting for the opportunity, support in terms of refuge is also found to be essential, especially for the poor while they undertake regional tours. Causal models focusing on aggregated general health tours and specific regional tours were estimated separately to comprehend the implicit social interactions and their effects on the patient as well as the companions. The research demonstrated that accessibility barriers affect not only the ill, but also those associated with them and at times adversely. Segregation of regional tours illustrated the gaps, which instigated such tours and also might aid in health infrastructure planning as a whole.

  12. Is profitability a good proxy for efficiency? Evidence from the subsector of tour operators

    Directory of Open Access Journals (Sweden)

    Hedija Veronika

    2017-12-01

    Full Text Available The goal of the paper is to evaluate the economic efficiency of tour operators in the Czech Republic in the period 2007-2014 using data envelopment analysis (DEA models and prove the link between economic efficiency and profitability and to find out if profitability is a good proxy for economic efficiency. Data was exported from the database Albertina CZ Gold Edition. We calculated the efficiency score using CCR (Charnes, Cooper and Rhodes and BCC (Banker, Charnes and Cooper models based on 3 inputs and 1 output. In the years 2007 to 2010, the efficiency score of almost all the companies was higher than 0.5; however, in years since 2011, we revealed significant differences in the efficiency of individual firms and only about 40 percent of tour operators achieved an efficiency score higher than 0.5. Using Pearson and Spearman correlation coefficients, our findings show that, in the case of the Czech tour operator market, profitability ratios do not correspond with firm efficiency. Profitability ratios are not a good proxy for economic efficiency and should not be used as the only firm criterion of performance.

  13. Business Ethics of Tour Operators – The Case Study of TUI

    Directory of Open Access Journals (Sweden)

    Marija Šuleić

    2014-10-01

    Full Text Available A large number of participants in tourism, both in offer and in demand, has conditioned the need for the creation ethical codices based on legislative regulations and moral principles. Among central figures in tourism, there are travel agencies and tour operators, the intermediaries between service providers and service users, in other words, passengers. The tour operators who are engaged in initiating tourism provide the services on foreign markets and tend to adapt their business to the laws and customs of the countries in which they run a business. TUI, as a leading European tour operator, which has even its representation in Serbia, can be a good example of the implementation of its business codes of ethics, but also adapting to the business customs being valid in the country in which TUI operates. Because of this, the aim of this work was to examine under what ethical standards TUI operates in Serbia in the domain of different stakeholders. The results of the research can be useful for different stakeholders.

  14. Obstacles Facing Promoting Tourism for Islamic Landmarks from the Perspective of Tour Operators in Egypt

    Directory of Open Access Journals (Sweden)

    Suzan Bakri Hassan

    2015-05-01

    Full Text Available The UNESCO launched a campaign #unite4heritage in Egypt to defeat extremism and intolerance. The message of such campaigne is peace, dialogue and unity embedded in cultural heritage. As culture and tourism are linked together, such message could be delivered through improving culture heritage tourism in Egypt. Islamic landmarks  are considered as a part of human heritage. Therefore, the purpose of this study is to identify how much tour operators in Egypt include Islamic landmarks in their programs to determine the obstacles facing promoting cultural tourism in Islamic landmarks' areas. Additionally, the study would identify positive results in the case of developing heritage tourism in Egypt. To achieve a high result, a survey approach was employed to collect data from 100 tour operators, using a completed questionnaire technique as well as a Likert Scale and statistical models in order to test and interpret the research outcomes. The research findings indicated that although tour operators in Egypt are convinced of the significance of the Islamic landmarks, there is no contradiction between creating global understanding and at the same time achieving benefit to the local community. However, there is a range of obstacles facing promoting such type of tourism in Egypt. Keywords: Culture heritage tourism, community, Egypt, Islamic civilization.

  15. CERN hosts Tour du canton de Genève stage

    CERN Multimedia

    2004-01-01

    CERN's John Osborne (TS) at the start of the 10 km with more than 1700 other runners. Good luck to the CERN runners in the forthcoming stages! CERN hosted the first stage of the 10th Tour du canton de Genève on the evening of Wednesday 26 May. The Tour du canton is an annual race run in four stages over four weeks, and this year started at CERN as part of the Golden Jubilee celebrations. The event attracted over 2000 runners, including over 40 from CERN, as well as a large crowd of onlookers. The 10.5 km route started and finished outside CERN's Main Building, taking in the Swiss countryside, crossing into France and coming back through the tunnel linking the two CERN sites. CERN runners finished in second place in the Enterprise category just 13 seconds behind Rolex S.A., setting up an exciting contest for the remaining stages at Bernex, Meyrin and Jussy.Results are on the Tour du canton website.

  16. A free ride? An analysis of the association of casino bus tours and problem gambling among older adults.

    Science.gov (United States)

    van der Maas, Mark; Mann, Robert E; Matheson, Flora I; Turner, Nigel E; Hamilton, Hayley A; McCready, John

    2017-12-01

    Little research has examined the relationship between incentives used by gambling venues to attract customers and the experience of gambling-related harm. Organized and subsidized bus tours are a common example of such incentives. The aim of this study was to examine whether bus-tour patronage was associated with increased odds of problem gambling among older adults. This study also compared rates of bus-tour use by socio-demographic characteristics and gambling behaviours. Pearson's χ 2 tests and Mann-Whitney U-tests were applied for bivariate analyses. Multivariate generalized mixed-effects regression modelling was used to examine the relationship between bus-tour patronage and problem gambling while controlling for possible confounding factors. Seven gambling venues located in Central and Southwestern Ontario, Canada. A total of 1978 gambling venue patrons over the age of 55 years. Problem gambling as indicated by the Problem Gambling Severity Index, bus-tour patronage in the 12 months prior to the survey, spending per gambling visit and past-month slot machine participation. Regression analyses showed that bus-tour patronage was associated with higher odds of problem gambling [odds ratio (OR) = 1.71, confidence interval (CI) = 1.06, 2.76] after controlling for several demographic characteristics, type of gambling and gambling expenditures. Bivariate analyses showed past-year bus-tour patronage was associated with more frequent slot machine play (χ 2 = 48.16, P casino visit (P < 0.001). Compared with non-patrons, bus tour patrons were more likely to be female (χ 2 = 21.92, P < 0.001), born outside Canada (χ 2 = 113.18, P < 0.001), above the age of 75 (χ 2 = 24.02, P < 0.001) and retired (χ 2 = 16.60, P < 0.001). When adjusting for potential confounders among older adults, using bus tours to access Canadian gambling venues is associated with increased risk of problem gambling. Bus-tour patrons are more likely to be female, born outside

  17. Virtual tours as a new teaching tool in geoscience: an example from the Western Alps

    Science.gov (United States)

    Berger, Antoine; Champagnac, Jean-Daniel; Nomade, Jérome

    2013-04-01

    , these panorama can be linked together to travel from place to place. Last, but not least, the display of any type of information (video of the last year teachers' explanation, close up of a structure, graphic plot, text content, interpreted geological sections etc.) can be integrated in the virtual tour. From this, it is easy to build a full educational virtual tour that can include the information provided in the field book, and even become the field book itself. These virtual tours can be used with any device (laptop, tablet, smartphone...), hence have the potential become key players in field teaching. Finally, these virtual tours can help physically impaired students to complete their geological curriculum with the indispensable field experience they would not have had otherwise. Here we present an example of such a virtual tour build in 2012 across the European Alps during the 1st International Field Course organized by Grenoble University, ETH Zürich and Milano University. This virtual tour covers the Grimsel Pass Aar Massif Hercynian Basement (granite, shear zone and the underground NAGRA test site), the Zermatt area (two continents and two oceans packed together), the Aiguille du Midi incredible overview on most of the W-Alps, and the back limb of the Nappe de Morcles and its relation with the surrounding blocks. Link to the virtual tour: http://www.alpesphoto.com/temp/visites/Suisse/build/virtualtour.swf

  18. Rozšíření produktové nabídky cestovní agentury Europani-tour

    OpenAIRE

    Gerasimenko, Elizaveta

    2017-01-01

    Title: Innovation of product offer for travel agency Europani-tour. Project goals: The main objective of this bachelor thesis is to create the own model trips with sport focus for the company Europani-tour. Method: In my thesis I used descriptive case study using a document monitoring and qualitative interview. Results: I created a new product - seven trips with sport focus for the travel agency Europani- tour. Before fulfillment of the main objective I have done a situational analysis of spo...

  19. Corrosion and solubility in a TSP-buffered chemical environment following a loss of coolant accident: Part 3—Calcium

    Energy Technology Data Exchange (ETDEWEB)

    Olson, Sterling; Ali, Amir; LaBrier, Daniel [Department of Nuclear Engineering, University of New Mexico (United States); Blandford, Edward D, E-mail: edb@unm.edu [Department of Nuclear Engineering, University of New Mexico (United States); Howe, Kerry [Department of Civil Engineering, University of New Mexico (United States)

    2016-04-15

    Highlights: • Calcium leaching from NUKON fiberglass in borated TSP-buffered solution is independent of the level of fiberglass destruction. • The initial calcium release rate and the maximum calcium concentration increases with increased fiber concentration. • The calcium release in solution has a repeatable pattern of four distinct regions (prompt release, metastable, autocatalytic drop, and stable region) for all experiments. • Magnesium plays a significant role in initiating calcium precipitation in TSP-buffered environment. • Head loss through multi-constituents debris beds was found to increase progressively in all calcium concentration regions. - Abstract: Calcium that leaches from damaged or destroyed NUKON fiberglass in containment post a loss of coolant accident (LOCA) could lead to the formation of chemical precipitates. These precipitates could be filtered through the accumulated fibrous debris on the sump screen and compromising the emergency core cooling system (ECCS) sump pump performance. Reduced-scale leaching experiments were conducted on three solution inventory scales—bench (0.5 L), vertical column (31.5 L), and tank (1136 L) using three different flow conditions, and fiberglass concentrations (1.18–8 g/L) to investigate calcium release from NUKON fiber. All experiments were conducted in simulated post-LOCA water chemistry. (∼220 mM boric acid with ∼5.8 mM trisodium phosphate (TSP) buffer). Prior to the leaching tests, a preliminary experiment was carried out on the bench scale to determine the effect of the fiber preparation (unaltered and blended) method on calcium leaching. Results indicate that the extent of fiberglass destruction does not affect the amount of calcium released from fiberglass. Long-term calcium leach testing at constant temperature (80 °C) in borated TSP-buffered solution had repeatable behavior on all solution scales for different fiberglass concentrations. The calcium-leaching pattern can be divided into

  20. Uzņēmuma McDonalds konkurētspējas novērtēšanas un tās uzlabošanas iespējas

    OpenAIRE

    Artemjeva, Anžela

    2012-01-01

    Bakalaura darba tēma – „Uzņēmuma McDonalds konkurētspējas novērtēšana un tās uzlabošanas iespējas”. Bakalaura darba mērķis-pamatojoties uz teorētiskām atziņām par konkurenci un konkurētspēju, izpētīt SIA McDonalds konkurētspēju tirgū un tās pilnveidošanas iespējas balstoties uz Latvijas, Lietuvas un Igaunijas investīciju nozares analīzes datu rezultātiem, izdarīt secinājumus un sniegt priekšlikumus SIA McDonalds konkurētspējas uzlabošanai. Bakalaura darba izstrādes gaitā autore ir izstr...

  1. Experiences of using mobile technologies and virtual field tours in Physical Geography: implications for hydrology education

    Directory of Open Access Journals (Sweden)

    D. G. Kingston

    2012-05-01

    Full Text Available Education in hydrology is changing rapidly due to diversification of students, emergent major scientific and practical challenges that our discipline must engage with, shifting pedagogic ideas and higher education environments, the need for students to develop new discipline specific and transferrable skills, and the advent of innovative technologies for learning and teaching. This paper focuses on new technologies in the context of learning and teaching in Physical Geography and reflects on the implications of our experiences for education in hydrology. We evaluate the experience of designing and trialling novel mobile technology-based field exercises and a virtual field tour for a Year 1 undergraduate Physical Geography module at a UK university. The new exercises are based on using and obtaining spatial data, operation of meteorological equipment (explained using an interactive DVD, and include introductions to global positioning systems (GPS and geographical information systems (GIS. The technology and exercises were well received in a pilot study and subsequent rolling-out to the full student cohort (∼150 students. A statistically significant improvement in marks was observed following the redesign. Although the students enjoyed using mobile technology, the increased interactivity and opportunity for peer learning were considered to be the primary benefits by students. This is reinforced further by student preference for the new interactive virtual field tour over the previous "show-and-tell" field exercise. Despite the new exercises having many advantages, exercise development was not trivial due to the high start-up costs, the need for provision of sufficient technical support and the relative difficulty of making year-to-year changes (to the virtual field tour in particular. Our experiences are highly relevant to the implementation of novel learning and teaching technologies in hydrology education.

  2. Experiences of using mobile technologies and virtual field tours in Physical Geography: implications for hydrology education

    Science.gov (United States)

    Kingston, D. G.; Eastwood, W. J.; Jones, P. I.; Johnson, R.; Marshall, S.; Hannah, D. M.

    2012-05-01

    Education in hydrology is changing rapidly due to diversification of students, emergent major scientific and practical challenges that our discipline must engage with, shifting pedagogic ideas and higher education environments, the need for students to develop new discipline specific and transferrable skills, and the advent of innovative technologies for learning and teaching. This paper focuses on new technologies in the context of learning and teaching in Physical Geography and reflects on the implications of our experiences for education in hydrology. We evaluate the experience of designing and trialling novel mobile technology-based field exercises and a virtual field tour for a Year 1 undergraduate Physical Geography module at a UK university. The new exercises are based on using and obtaining spatial data, operation of meteorological equipment (explained using an interactive DVD), and include introductions to global positioning systems (GPS) and geographical information systems (GIS). The technology and exercises were well received in a pilot study and subsequent rolling-out to the full student cohort (∼150 students). A statistically significant improvement in marks was observed following the redesign. Although the students enjoyed using mobile technology, the increased interactivity and opportunity for peer learning were considered to be the primary benefits by students. This is reinforced further by student preference for the new interactive virtual field tour over the previous "show-and-tell" field exercise. Despite the new exercises having many advantages, exercise development was not trivial due to the high start-up costs, the need for provision of sufficient technical support and the relative difficulty of making year-to-year changes (to the virtual field tour in particular). Our experiences are highly relevant to the implementation of novel learning and teaching technologies in hydrology education.

  3. CityGuideTour Toruń - tourist application using augmented reality

    Science.gov (United States)

    Węgrzyn, Magdalena; Mościcka, Albina

    2017-12-01

    The aim of the article is to show the possibilities of augmented reality in the fi eld of geodesy and cartography. It discusses the concept of augmented reality, its origins and development, as well as areas of the existing applications. The practical functioning of augmented reality in the area of geodesy and cartography is presented on the example of an application developed for the tourist city of Toruń, created with the use of CityGuideTour software. The principles of developing an application and the way it operates are also discussed. As a result, a fully operational bilingual application is available free of charge on the Web.

  4. Berlin: Sustainability and Tour Guides in a Partial Dark Tourism Destination

    OpenAIRE

    Asaf Leshem

    2013-01-01

    When guiding in Berlin about the Holocaust or about the Cold War, tour guides often hear the phrase: “I didn’t come here for that, but I want to see that as well...” Many of Berlin’s 10 Million visitors per year claim to have an attraction towards both the morbid and the lighter side of the city. Following from that popular sentiment it is argued that Berlin can be defined as a Partial Dark Tourism Destination. As such, it is further argued that Berlin is prone to an increase of socio-econom...

  5. Using Computer-Based Virtual Tours to Assist Persons With Disabilities

    Directory of Open Access Journals (Sweden)

    Jeffrey M. Broida

    2003-07-01

    Full Text Available Results of a recent study concerning computer technology and people with disabilities indicate that virtual reality tours are effective in conveying information and, in some cases, reducing anxiety. One hundred and ten subjects with physical disabilities participated in the study, and seven quantitative and qualitative instruments were used to assess study variables. Three physical locations were recreated virtually and include interactivity, captioning, digital audio and video, mapping, and other features. The implications may be valuable in both physical and virtual educational settings as educators strive to serve a growing student population.

  6. Photovoltaics R and D: A tour through the 21st century

    Energy Technology Data Exchange (ETDEWEB)

    Kazmerski, L. L.

    2000-05-15

    The future investments for photovoltaics research and development are contemplated for this new millennium. Current technologies are used as the foundation for what might be expected for the next 50 years. A tour is conducted through what coming generations can anticipate for this technology; emphasizing non-conventional applications beyond the expected. Next-generation research approaches are predicted indicating the horizon of PV technology. Conjectures of those PV and related technologies that are beyond this horizon are presented, with prognosis what the coming generations might have as their conventional energy sources.

  7. Aplikasi E-Tour Guide dengan Fitur Pengenalan Image Menggunakan Metode Haar Classifier

    Directory of Open Access Journals (Sweden)

    Derwin Suhartono

    2013-12-01

    Full Text Available Smartphone has became an important instrument in modern society as it is used for entertainment and information searching except for communication. Concerning to this condition, it is needed to develop an application in order to improve smart phone functionality. The objective of this research is to create an application named E-Tour Guide as a tool for helping to plan and manage tourism activity equipped with image recognition feature. Image recognition method used is the Haar Classifier method. The feature is used to recognize historical objects. From the testing result done to 20 images sample, 85% accuracy is achieved for the image recognition feature.

  8. [The German Museum for the History of Medicine: a museum tour from the perspective of urology].

    Science.gov (United States)

    Ruisinger, M M

    2012-08-01

    In 1973, Germany's first museum of the history of medicine was founded in the former anatomical theatre of Ingolstadt University. Today, the baroque building with its beautiful medical garden is one of the attractions of the old city of Ingolstadt. The paper gives a round tour through the permanent exhibition, the medical technology wing and the herbal garden. The emphasis is put on those objects and plants which have a connection to the history of urology, from a "ladies urinal" to the world's first ESWL apparatus.

  9. Performance of electric and hybrid vehicles at the 1995 American Tour de Sol

    Energy Technology Data Exchange (ETDEWEB)

    Quong, S.; LeBlanc, N.; Buitrago, C.; Duoba, M.; Larsen, R.

    1995-12-31

    Energy consumption and performance data were collected on more than 40 electric and hybrid vehicles during the 1995 American Tour de Sol. At this competition, one electric vehicle drove 229 miles on one charge using nickel metalhydride batteries. The results obtained from the data show that electric vehicle efficiencies reached 9.07 mi./kWh or 70 equivalent mpg of gasoline when compared to the total energy cycle efficiency of electricity and gasoline. A gasoline-fueled 1995 Geo Metro that drove the same route attained 36.4 mpg.

  10. SIMULTANEOUS SCHEDULING AND OPERATIONAL OPTIMIZATION OF MULTIPRODUCT, CYCLIC CONTINUOUS PLANTS

    Directory of Open Access Journals (Sweden)

    A. Alle

    2002-03-01

    Full Text Available The problems of scheduling and optimization of operational conditions in multistage, multiproduct continuous plants with intermediate storage are simultaneously addressed. An MINLP model, called TSPFLOW, which is based on the TSP formulation for product sequencing, is proposed to schedule the operation of such plants. TSPFLOW yields a one-order-of-magnitude CPU time reduction as well as the solution of instances larger than those formerly reported (Pinto and Grossmann, 1994. Secondly, processing rates and yields are introduced as additional optimization variables in order to state the simultaneous problem of scheduling with operational optimization. Results show that trade-offs are very complex and that the development of a straightforward (rule of thumb method to optimally schedule the operation is less effective than the proposed approach.

  11. SIMULTANEOUS SCHEDULING AND OPERATIONAL OPTIMIZATION OF MULTIPRODUCT, CYCLIC CONTINUOUS PLANTS

    Directory of Open Access Journals (Sweden)

    Alle A.

    2002-01-01

    Full Text Available The problems of scheduling and optimization of operational conditions in multistage, multiproduct continuous plants with intermediate storage are simultaneously addressed. An MINLP model, called TSPFLOW, which is based on the TSP formulation for product sequencing, is proposed to schedule the operation of such plants. TSPFLOW yields a one-order-of-magnitude CPU time reduction as well as the solution of instances larger than those formerly reported (Pinto and Grossmann, 1994. Secondly, processing rates and yields are introduced as additional optimization variables in order to state the simultaneous problem of scheduling with operational optimization. Results show that trade-offs are very complex and that the development of a straightforward (rule of thumb method to optimally schedule the operation is less effective than the proposed approach.

  12. Serum levels of TSP-1, NF-κB and TGF-β1 in polycystic ovarian syndrome (PCOS) patients in northern China suggest PCOS is associated with chronic inflammation.

    Science.gov (United States)

    Liu, Meimei; Gao, Jiayin; Zhang, Yanhua; Li, Peiling; Wang, Hongli; Ren, Xiaopang; Li, Changmin

    2015-12-01

    The objective of this study was to determine the levels of thrombospondin-1 (TSP-1), transforming growth factor-β1 (TGF-β1) and nuclear factor kappaβ (NF-κβ) in polycystic ovarian syndrome (PCOS) patients with and without insulin resistance and after treatment with cyproterone acetate/ethinyloestradiol with or without concomitant metformin. Prospective. Patients with PCOS and healthy women were recruited. Patients were subdivided into obese and nonobese based on body mass index. Patients with PCOS were also grouped according to homoeostasis model assessment-insulin resistance (HOMA-IR) ≥ 2·69 or PCOS phenotype. Patients with PCOS-IR were treated with a 6-month course of cyproterone acetate/ethinyloestradiol with or without concomitant metformin. Inflammatory markers were examined at baseline, and after 6 months of treatment. A total of 445 women with PCOS (mean age 25·9 ± 2·7 years; 298 obese, 147 nonobese) and 213 normal controls (mean age 24·9 ± 3·0 years) were included. Regardless of obesity status, testosterone, free androgen index (FAI), luteinizing hormone/follicle-stimulating hormone (LH/FSH) ratio, HOMA-IR, TSP-1 and NF-κB in the PCOS groups were significantly higher than in the control group, whereas TSP-1 was lower in the PCOS groups (all, P PCOS without IR had lower TSP-1 levels than control patients (P Treatment with cyproterone acetate/ethinyloestradiol with addition of metformin reduced the level of NF-κB, TGF-β1 and HOMA-IR and increased the level of TSP-1. These results support the association between PCOS and chronic inflammation. © 2015 John Wiley & Sons Ltd.

  13. Touring Berlin

    OpenAIRE

    Farías, Ignacio

    2009-01-01

    Mittels einer Untersuchung von standardisierten Praktiken (Stadtrundgängen und Stadtrundfahrten) und Dispositiven (Stadtkarten, Reiseführer) fürs „Touren“ von Städten zeigt diese Dissertation, (1) wie die Stadt Berlin in ein virtuelles Objekt, nämlich, einen touristischen Zielort, transformiert wird, ( 2) wie diese Transformation nicht nur durch die Bewegung von Touristen im Raum und das Unterwegssein ermöglicht wird, sondern durch touristische Kommunikation über die Stadt, und (3) wie diese ...

  14. World Tour

    CERN Multimedia

    Tauxe,H

    H.C.Tauxe est Dr.ès lettres de l'Université de Lausanne et a enseigné la philosophie jusqu'en 1962. Ensuite il s'est tourné vers le journalisme, et dans ce cadre il a fait le voyage, qui sera le thème de sa conférence, en suivant ce qui a écrit Jules Verne.

  15. Superconducted tour

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1988-09-15

    Superconductivity - the dramatic drop in electrical resistance in certain materials at very low temperatures - has grown rapidly in importance over the past two or three decades to become a key technology for high energy particle accelerators. It was in this setting that a hundred students and 15 lecturers met in Hamburg in June for a week's course on superconductivity in particle accelerators, organized by the CERN Accelerator School and the nearby DESY Laboratory.

  16. Cartographic Tours

    DEFF Research Database (Denmark)

    Møhl, Perle

    2012-01-01

    This is one of three chapters about authoritative, scientific presentations of the Emerillon/Teko of French Guiana and their environment: 1) historiography, 2) cartography and 3) fewness and the politics of numbers. The chapter argues that cartography is a very terrestrial endeavour: although maps......-fledged reproductions of the territory through satellite imagery. The chapter relates two instances of mapmaking where tribulations, errors and misunderstandings on the ground are transformed into authoritative representations/maps, giving rise to a series of clashes between people and groups in the concerned...

  17. José Nicolás de Azara : un icono del Grand Tour

    Directory of Open Access Journals (Sweden)

    Jorge García Sánchez

    2008-01-01

    Full Text Available José Nicolás de Azara, bien conocido como Agente de Preces y ministro plenipotenciario ante la Santa Sede, fue tal vez la personalidad española de mayor influencia en los círculos intelectuales y artísticos de la Roma del siglo XVIII. Su asumida función de guía ilustrado y su vocación pedagógica para con los jóvenes viajeros lo convirtieron en un auténtico icono del Grand Tour.José Nicolás de Azara, well known as Agente de Preces (Agent of Supplications and ministro plenipotenciario (Plenipotentiary Minister in the Holy See, was perhaps the most influential Spanish personality in the intellectual and artistic circles of Eighteenth-Century Rome. His wilful function of enlightened guide and his pedagogic attitude towards the young travellers made of him an authentic icon of the Grand Tour.

  18. English for Tour Guide: A Need Analysis of a Contextual-Based Language Teaching

    Directory of Open Access Journals (Sweden)

    Ratminingsih Ni Made

    2018-01-01

    Full Text Available This paper reports the results of need analysis of English for Specific Purposes (ESP for local tour guides in two villages in Buleleng regency. This research is a descriptive qualitative study involving 56 tour guides, in which 30 were based in Ambengan village and 26 others were posted in Sambangan village. There were three instruments applied to obtain the research data such as observation sheet, questionnaire, and interview guide. Findings from the observation showed that the two villages had waterfalls and terraced rice fields as the main potencies. Additionally, the questionnaire specifying the target need showed that both groups had low speaking skill (56.05% even the rest of them (43.95% understood English, but was not able to speak English at all. Furthermore, they all required oral English, speaking (69% and listening (24.5%. Seen from learning need, they demanded conversation (90.5% as the most important learning experience. The results from interview proved that 92.5% local guides had no academic background in English. From those findings, it can be summed up that they need contextual-based English learning to accomplish their jobs in a more professional way through non formal education.

  19. Tour de France Champions born or made: where do we take the genetics of performance?

    Science.gov (United States)

    Moran, Colin N; Pitsiladis, Yannis P

    2017-07-01

    Cyclists in the Tour de France are endurance specialists. Twin and family studies have shown that approximately 50% of the variance in a number of performance-related phenotypes (whether measured at baseline, i.e., natural talent, or in response to training) including those important to cycling can be explained by genetic variation. Research into the specific genetic variants that are responsible has identified over 200 genes containing common genetic variants involved in the genetic predisposition to physical performance. However, typically these explain only a small portion of the variance, perhaps 1-2% and collectively they rarely explain anything approaching the 50% of the variance identified in the twin and family studies. Thus, there is a gap in our understanding of the relationship between heritability and performance. This gap may be bridged by investigation of rare variants or epigenetic variation or by altering study designs through increased collaborations to pool existing cohorts together. Initial findings from such efforts show promising results. This mini-review will touch on the genetics and epigenetics of sporting performance, how they relate to cyclists in the Tour de France and where best future efforts may be directed as well as discuss some preliminary research findings.

  20. A study on relationship between cultural intelligence and cross-cultural adjustment in tour management

    Directory of Open Access Journals (Sweden)

    Mahdi Karroubi

    2014-06-01

    Full Text Available The purpose of the present study was to examine the effects of cultural intelligence (CQ and emotional intelligence (EI on a tour leader’s adjustment in a different cultural environment. Data were collected from 330 outgoing tour leaders in Tehran, Iran. The construct validity was confirmed by using confirmatory factor analysis. The data were analyzed using correlation analysis and path analysis to test the effect of CQ on cross-cultural adjustment, and the moderating effect of EI on the relationship between CQ and cross-cultural adjustment. The results showed that CQ had a positive effect on cross-cultural adjustment. In addition, we found that CQ had a positive effect on EI. The findings of the research showed that emotional intelligence in not significantly the mediator variable. Emotional intelligence has a positive and significant effect on cross-cultural adjustment. The findings of this study contribute to the body of knowledge in the field of CQ and cross-cultural research, and it provides practical implications for individuals seeking to improve their cross-cultural effectiveness, enhancing their cultural intelligence and emotional intelligence, specifically in tourism industry.

  1. Randomized clinical trial of immersive virtual reality tour of the operating theatre in children before anaesthesia.

    Science.gov (United States)

    Ryu, J-H; Park, S-J; Park, J-W; Kim, J-W; Yoo, H-J; Kim, T-W; Hong, J S; Han, S-H

    2017-11-01

    A virtual reality (VR) tour of the operating theatre before anaesthesia could provide a realistic experience for children. This study was designed to determine whether a preoperative VR tour could reduce preoperative anxiety in children. Children scheduled for elective surgery under general anaesthesia were randomized into a control or VR group. The control group received conventional information regarding anaesthesia and surgery. The VR group watched a 4-min video showing Pororo, the famous little penguin, visiting the operating theatre and explaining what is in it. The main outcome was preoperative anxiety, assessed using the modified Yale Preoperative Anxiety Scale (m-YPAS) before entering the operating theatre. Secondary outcomes included induction compliance checklist (ICC) and procedural behaviour rating scale (PBRS) scores during anaesthesia. A total of 69 children were included in the analysis, 35 in the control group and 34 in the VR group. Demographic data and induction time were similar in the two groups. Children in the VR group had a significantly lower m-YPAS score than those in the control group (median 31·7 (i.q.r. 23·3-37·9) and 51·7 (28·3-63·3) respectively; P anxiety and increasing compliance during induction of anaesthesia in children undergoing elective surgery. Registration number: UMIN000025232 (http://www.umin.ac.jp/ctr). © 2017 BJS Society Ltd Published by John Wiley & Sons Ltd.

  2. HEALTH INFO Information from the CHISBoard and Personnel Division: ABOUT BILLS FROM HOPITAL DE LA TOUR

    CERN Multimedia

    1999-01-01

    The tariff agreement signed by CERN (and other international organisations) with Hôpital de La Tour specifies that all bills paid within 30 days of the date of the invoice will enjoy a discount, to be deducted by the payer. The bills are labelled with a message to this effect.Physicians' fees, personal expenses as well as services from outside providers (e.g. ambulance companies or external laboratories) are however not part of the discount agreement. Bills for hospitalisation (i.e. with a stay in hospital longer than 28h) are normally directly paid by AUSTRIA, acting as a third-party payer.In May this year, Hôpital de La Tour introduced a new (Y2K compliant) accounting and invoicing system. This implementation did not go as smoothly as planned and delayed the issuing of bills by two months. During the summer period, a special team of temporary staff was put in place to catch up on the delay. As a result of this, some bills were produced that contained errors and the sticky label mentionin...

  3. Double victory for CERN at the "Tour du canton de Genève"

    CERN Multimedia

    CERN Running Club

    2016-01-01

    Once again, the CERN Running Club has caused a stir at the Tour du Canton de Genève.   The team “Entreprise femmes” with, from left to right, Lucie Baudin, Joanna Stanyard, Maïté Barroso-Lopez, Ana Garcia-Tabares and Elisa Garcia-Tabares (Claire Hauw, also member of the team, is absent from the photo). This year, the event, which is held over four stages in the Geneva area, took place on Wednesday evenings from 25 May to 15 June. CERN shone in the “Entreprise” categories, taking first place in both the female and male group rankings. There were also some excellent individual results, with particularly impressive times in the “Vétérans 2” category (Camille Ruiz Llamas and Graham Dore were placed third and sixth respectively). See the full results on the Tour website and on the CERN Running Club website.

  4. KARAKTERISTIK, MOTIVASI DAN KEPUASAN WISATAWAN NUSANTARA YANG BERKUNJUNG KE DAYA TARIK WISATA CITY TOUR DENPASAR

    Directory of Open Access Journals (Sweden)

    Pius Tenouye

    2017-07-01

    Full Text Available This study aims to determine the characteristics, motivation and satisfaction of tourists who visit the tourist attraction city tour Denpasar. Research methods include: observation, questionnaires to 100 tourists, literature study and documentation and descriptive qualitative as the analysis techniques. The results showed that the characteristics of tourists dominated 81% aged 15-30 years, 60% male, 79% are not married, university level education 71%, 77% students, 56% of the island of Java, resources through friends / family 36 %, 62% ground transportation, hotel accommodations as a means of 65%, frequency of visit to Bali 2-3 times 75%, 45% choose to visit, type of visit 65%, 65% of people who had been invited, organizers of 75%. Furthermore, intrinsic motivation tourists dominated by indicators want to know the Balinese art with scale score of 4.21 (strong, while extrinsic motivation is dominated indicators admission fee affordable fascination with score of 4.20 (strong. In general, tourists are satisfied with the tourist attraction, and the indicator that dominates is the physical aspect of the form of security with score of 4.33 (very satisfied and non-physical aspects of the hospitality and courtesy clerk with score of 4.97 (very satisfied. Through this research is expected the municipality, manager of a tourist attraction can improve the quality and attractiveness of city tour service in accordance with the characteristics, motivation and satisfaction of tourists so the frequency and the number of tourist arrivals increased evenly.

  5. A MASSive Laboratory Tour. An Interactive Mass Spectrometry Outreach Activity for Children

    Science.gov (United States)

    Jungmann, Julia H.; Mascini, Nadine E.; Kiss, Andras; Smith, Donald F.; Klinkert, Ivo; Eijkel, Gert B.; Duursma, Marc C.; Cillero Pastor, Berta; Chughtai, Kamila; Chughtai, Sanaullah; Heeren, Ron M. A.

    2013-07-01

    It is imperative to fascinate young children at an early stage in their education for the analytical sciences. The exposure of the public to mass spectrometry presently increases rapidly through the common media. Outreach activities can take advantage of this exposure and employ mass spectrometry as an exquisite example of an analytical science in which children can be fascinated. The presented teaching modules introduce children to mass spectrometry and give them the opportunity to experience a modern research laboratory. The modules are highly adaptable and can be applied to young children from the age of 6 to 14 y. In an interactive tour, the students explore three major scientific concepts related to mass spectrometry; the building blocks of matter, charged particle manipulation by electrostatic fields, and analyte identification by mass analysis. Also, the students carry out a mass spectrometry experiment and learn to interpret the resulting mass spectra. The multistage, inquiry-based tour contains flexible methods, which teach the students current-day research techniques and possible applications to real research topics. Besides the scientific concepts, laboratory safety and hygiene are stressed and the students are enthused for the analytical sciences by participating in "hands-on" work. The presented modules have repeatedly been successfully employed during laboratory open days. They are also found to be extremely suitable for (early) high school science classes during laboratory visit-focused field trips.

  6. Franchising - liiketoiminnan käynnistämiseen vaadittavat toimenpiteet ja haasteet organisaatiossa : case: Touring Cars Finland Oy

    OpenAIRE

    Aaltonen, Suvi

    2013-01-01

    Tämän opinnäytetyön tavoitteena oli selvittää franchise-liiketoiminnan käynnistämiseen liittyviä toimenpiteitä ja haasteita organisaatiossa. Opinnäytetyön teoriaosuus selvittää niitä asioita, joita franchise-antajan ja –ottajan on huomioitava franchise-liiketoimintaa aloittaessaan. Case-yrityksenä on suomalainen Touring Cars Finland Oy. Case-yritys siirtyy käyttämään franchise-liiketoimintamallia vuosien 2013–2018 aikana yrityksen kaikissa toimipisteissä Suomessa ja ulkomailla. Touring Ca...

  7. Review of The Joy of x: A Guided Tour of Math, from One to Infinity by Steven Strogatz

    OpenAIRE

    Michael T. Catalano

    2014-01-01

    Strogatz, Steven. The Joy of x: A Guided Tour of Math, from One to Infinity, (New York, NY, Houghton Mifflin Harcourt, 2012). 316 pp. ISBN 978-0-547-51765-0 The Joy of x: A Guided Tour of Math, from One to Infinity, by Steven Strogatz, is an engaging and example-filled argument for mathematics as a valuable and enjoyable activity. The thirty chapters are divided into six parts, entitled Numbers, Relationships, Shapes, Change, Data, and Frontiers. The discussion ranges from intuitive expl...

  8. An Application of Project-Based Learning on the Development of Young Local Tour Guides on Tai Phuan's Culture and Tourist Attractions in Sisatchanalai District, Sukhothai Province

    Science.gov (United States)

    Kerdpol, Sakon

    2016-01-01

    This paper presents an investigation of a research entitled, " An Application of Project-based Learning on the Development of Young Local Tour Guides on Tai Phuan's Culture and Tourist Attractions in Sisatchanalai District, Sukhothai Province. It was intended to develop young local tour guides on Tai Phuan's culture and tourist attractions in…

  9. 41 CFR 302-3.219 - Is there a limit on how many times I may receive reimbursement for tour renewal travel?

    Science.gov (United States)

    2010-07-01

    ... many times I may receive reimbursement for tour renewal travel? 302-3.219 Section 302-3.219 Public Contracts and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES RELOCATION....219 Is there a limit on how many times I may receive reimbursement for tour renewal travel? (a) If you...

  10. Biobjective Optimization and Evaluation for Transit Signal Priority Strategies at Bus Stop-to-Stop Segment

    Directory of Open Access Journals (Sweden)

    Rui Li

    2016-01-01

    Full Text Available This paper proposes a new optimization framework for the transit signal priority strategies in terms of green extension, red truncation, and phase insertion at the stop-to-stop segment of bus lines. The optimization objective is to minimize both passenger delay and the deviation from bus schedule simultaneously. The objective functions are defined with respect to the segment between bus stops, which can include the adjacent signalized intersections and downstream bus stops. The transit priority signal timing is optimized by using a biobjective optimization framework considering both the total delay at a segment and the delay deviation from the arrival schedules at bus stops. The proposed framework is evaluated using a VISSIM model calibrated with field traffic volume and traffic signal data of Caochangmen Boulevard in Nanjing, China. The optimized TSP-based phasing plans result in the reduced delay and improved reliability, compared with the non-TSP scenario under the different traffic flow conditions in the morning peak hour. The evaluation results indicate the promising performance of the proposed optimization framework in reducing the passenger delay and improving the bus schedule adherence for the urban transit system.

  11. 14 CFR Appendix A to Part 136 - Special Operating Rules for Air Tour Operators in the State of Hawaii

    Science.gov (United States)

    2010-01-01

    ... Operators in the State of Hawaii A Appendix A to Part 136 Aeronautics and Space FEDERAL AVIATION... Appendix A to Part 136—Special Operating Rules for Air Tour Operators in the State of Hawaii Section 1... flights conducted in the State of Hawaii under 14 CFR parts 91, 121, and 135. This appendix does not apply...

  12. Impact of touring, performance schedule, and definitions on 1-year injury rates in a modern dance company.

    Science.gov (United States)

    Bronner, Shaw; Wood, Lily

    2017-11-01

    There is ongoing debate about how to define injury in dance: the most encompassing one or a time-loss definition. We examined the relationship between touring, performance schedule and injury definition on injury rates in a professional modern dance company over one-year. In-house healthcare management tracked 35 dancers for work-related musculoskeletal injuries (WMSI), time-loss injuries (TLinj), complaints, and exposure. The year was divided into 6 segments to allow comparison of effects of performance, rehearsal, and touring. Injuries/segment were converted into injuries/1000-h dance exposure. We conducted negative binomial regression analysis to determine differences between segments, P ≤ 0.05. Twenty WMSI, 0.44 injuries/1000-h, were sustained over one-year. WMSI were 6 times more likely to occur in Segment-6, compared with other segments (incident rate ratio = 6.055, P = 0.031). The highest rate of TLinj and traumatic injuries also occurred in Segment-6, reflecting concentrated rehearsal, New York season and performances abroad. More overuse injuries occurred in Segment-2, an international tour, attributed to raked stages. Lack of methods to quantify performance other than injury may mask effects of touring on dancer's well-being. Tracking complaints permits understanding of stressors to specific body regions and healthcare utilisation; however, TLinj remain the most important injuries to track because they impact other dancers and organisational costs.

  13. (New) NASA Director Sean O'Keefe comes to Ames for employee briefing and tour. Meets with Roberto

    Science.gov (United States)

    2002-01-01

    (New) NASA Director Sean O'Keefe comes to Ames for employee briefing and tour. Meets with Roberto Cruz, National Hispanic University (seated, right) and Ames Center Director Dr. Henry McDonald follow the signing of the educational MOU between NHU and Ames.

  14. Orchestrating automobile technology : comfort, mobility culture, and the Construction of the ‘Family Touring Car’, 1917 – 1940

    NARCIS (Netherlands)

    Mom, G.P.A.

    2014-01-01

    During the social and technical construction of the affordable "family touring car" in both the United States and Europe, one of the urgent projects was the abatement of noise. As a part of the emergence of "automotive comfort,"noise abatement took place during one of the costliest operations in the

  15. Rehabilitation of the Visually Impaired in the Soviet Union. Report from a Study Tour to Moscow in 1977.

    Science.gov (United States)

    Kullberg, Kjell; Lindstrom, Jan-Ingvar

    The document reports on a 10-day tour to study rehabilitation facilities for the visually handicapped in the Soviet Union. Briefly described are the programs of the following institutions that were visited: Helmholtz Institute of Opthalmology, Specialized School Number 5 for Partially Sighted Children, Scientific Research Institute of Defectology,…

  16. 76 FR 62495 - Notice of Extension of Public Scoping Comment Period for the Air Tour Management Plan Program at...

    Science.gov (United States)

    2011-10-07

    ... Air Tour Management Plan (ATMP) for Golden Gate National Recreation Area (GGNRA) and Point Reyes... cooperating agency, has initiated development of ATMPs for GGNRA and the Seashore. The ATMP for GGNRA will... NPATMA, the objective of an ATMP shall be to develop acceptable and effective measures to mitigate or...

  17. Proceedings of a study tour, conference and workshop in Sweden, 5-10 June 1994

    Energy Technology Data Exchange (ETDEWEB)

    Aronsson, P; Perttu, K [eds.

    1994-12-31

    The present proceedings are the result of an international meeting within the frame of the International Energy Agency/Biomass Agreement (IEA/BA)/Task VIII through the activities on `Biological disposal of waste waters and sludges` and `Ecological/biological balances and conservation` organized by the Swedish University of Agricultural Sciences, Uppsala. The meeting was divided into a 2-day study tour, starting from southernmost Sweden and ending in Uppsala, during which visits were made to different vegetation filter experiments, and a 1-day conference with paper and poster presentations. In connection with the IEA meeting, a joint Swedish-Polish workshop was organized, mainly devoted to presentations of results from Polish investigations on large-scale vegetation filter use. Separate abstracts have been prepared for 29 of the 34 papers

  18. MULTI-VEHICLE COVERING TOUR PROBLEM: BUILDING ROUTES FOR URBAN PATROLLING

    Directory of Open Access Journals (Sweden)

    Washington Alves de Oliveira

    2015-12-01

    Full Text Available ABSTRACT In this paper we study a particular aspect of the urban community policing: routine patrol route planning. We seek routes that guarantee visibility, as this has a sizable impact on the community perceived safety, allowing quick emergency responses and providing surveillance of selected sites (e.g., hospitals, schools. The planning is restricted to the availability of vehicles and strives to achieve balanced routes. We study an adaptation of the model for the multi-vehicle covering tour problem, in which a set of locations must be visited, whereas another subset must be close enough to the planned routes. It constitutes an NP-complete integer programming problem. Suboptimal solutions are obtained with several heuristics, some adapted from the literature and others developed by us. We solve some adapted instances from TSPLIB and an instance with real data, the former being compared with results from literature, and latter being compared with empirical data.

  19. Nanotubule and Tour Molecule Based Molecular Electronics: Suggestion for a Hybrid Approach

    Science.gov (United States)

    Srivastava, Deepak; Saini, Subhash (Technical Monitor)

    1998-01-01

    Recent experimental and theoretical attempts and results indicate two distinct broad pathways towards future molecular electronic devices and architectures. The first is the approach via Tour type ladder molecules and their junctions which can be fabricated with solution phase chemical approaches. Second are fullerenes or nanotubules and their junctions which may have better conductance, switching and amplifying characteristics but can not be made through well controlled and defined chemical means. A hybrid approach combining the two pathways to take advantage of the characteristics of both is suggested. Dimension and scale of such devices would be somewhere in between isolated molecule and nanotubule based devices but it maybe possible to use self-assembly towards larger functional and logicalunits.

  20. [Evaluation of hospitalizations in the gastroenterology service of Gabriel Toure Hospital, Mali].

    Science.gov (United States)

    Diarra, M; Konate, A; Demble Doumbia, A; Kalle, A; Maiga, M Y

    2006-01-01

    The goal of this study was to appreciate principal affections and mortality and in gastroenterology service of Gabriel Touré Hospital. It is about a survey longitudinal that has permit to analyze patients who have been care. During study, 766 patients were unregistered. Mean age of patient was 45.17 years and a sex ratio (M/F) = 1.10. The rate of reference was 13.85%. The morbidity was dominated by HIV infection (29.90%) followed by Hepato-cellular Carcinoma (7.83%) and cirrhosis (4.05%). Mortality (18.41%) was dominated by the VIH infection, HCC and Cirrhosis. The precocious recourse to cares, the improvement of work conditions, the sensitization, the infectious illness prevention is factors that will permit a reduction of morbidity and hospital mortality.

  1. [Interdisciplinary training opportunities for residents in occupational medicine: the experience of the ERC Tour 2012].

    Science.gov (United States)

    Toninelli, E; Fostinelli, J; Rosen, M A; Lucchini, R; Apostoli, P

    2012-01-01

    This paper describes the experience of the School of Occupational Medicine of the University of Brescia at the current edition of the New York and New Jersey Education and Research Center--Historical Perspectives Tour on Occupational Safety and Health, that involved 5 different industrial and environmental sites, appropriate for understanding the complex occupational health and safety problems. In every site, the participants have interacted with workers and professionals and discussed about the specific work processes, to better understand the risk faced by the workers, occupational pathologies that can occur, personal protective equipment used and preventive measures adopted. This experience has been successful in provide interdisciplinary educations to occupational safety and health professionals in training in order to prepare them for the collaboration and cooperation required to solve the complex occupational health and safety problems they will face in their future careers.

  2. Viseu Mobile: A location based Augmented Reality tour guide for mobile devices

    Directory of Open Access Journals (Sweden)

    M.L. Martins

    2015-11-01

    Full Text Available This article reports on the project "Viseu na Palma da Mão", which is based on a Augmented Reality app for mobile devices, whose main purpose is to maximise the tourists’ experience when visiting the town of Viseu. The paper starts by presenting a reflection on Augmented Reality and its potential and applications, with a special emphasis on the tourism industry. The increasing possibility to access the Internet anytime, anywhere, together with the unprecedented growth of mobile device penetration has boosted the development of specific applications that seek to respond to the increasing demands of tourists. It is on this premise that the app Viseu Mobile emerges, seeking to enhance the constant use of mobile devices, and making them act as a personal tour guide, based on location based information. The different stages of development and different features of the application are also explained

  3. Sense of Place in Tourism and Leisure: the Case of Touring Skiers in Quebec

    Directory of Open Access Journals (Sweden)

    Romain Roult

    2016-07-01

    Full Text Available The concept of sense of place has become central in understanding various modern phenomena in leisure. Tourism promoters in outdoor recreation now emphasize opportunities to bond with nature, with ‘wild’ landscapes or with the authentic value of a destination. However, studying this tourism and recreation issue from the standpoint of ‘place’, which draws upon notions of attendance, identification and social and individual meaning, is lacking in modern studies. This paper, based on a quantitative approach using a questionnaire survey administered to touring skiers in Quebec (n=829, thus aims to present the links between various practice settings and the perceived meaning and identification that skiers attach to their practice sites.

  4. University of Virginia open-quotes virtualclose quotes reactor facility tours

    International Nuclear Information System (INIS)

    Krause, D.R.; Mulder, R.U.

    1995-01-01

    An electronic information and tour book has been constructed for the University of Virginia reactor (UVAR) facility. Utilizing the global Internet, the document resides on the University of Virginia World Wide Web (WWW or W) server within the UVAR Homepage at http://www.virginia. edu/∼reactor/. It is quickly accessible wherever an Internet connection exists. The UVAR Homepage files are accessed with the hypertext transfer protocol (http) prefix. The files are written in hypertext markup language (HTML), a very simple method of preparing ASCII text for W3 presentation. The HTML allows use of various hierarchies of headers, indentation, fonts, and the linking of words and/or pictures to other addresses-uniform resource locators. The linking of texts, pictures, sounds, and server addresses is known as hypermedia

  5. Magnetometer instrument team studies for the definition phase of the outer planets grand tour

    Science.gov (United States)

    Coleman, P. J., Jr.

    1972-01-01

    The objectives of magnetic field investigations on missions to the outer planets were defined as well as an instrumentation system, a program of studies and instrument development tasks was proposed for the mission definition phase of the Outer Planets Grand Tour project. A report on the status of this program is given. Requirements were also established for the spacecraft and the mission which would insure their compatibility with the magnetic field investigation proposed for the outer planets missions and developed figures of merit for encounter trajectories. The spacecraft-instrumentation interface and the on-board data handling system were defined in various reports by the Project Team and in the reports by the Science Steering Group. The defining program for exploring the outer planets within the more restrictive constraints of the Mariner Jupiter-Saturn project included defining a limited magnetic field investigation.

  6. Location and multi-depot vehicle routing for emergency vehicles using tour coverage and random sampling

    Directory of Open Access Journals (Sweden)

    Alireza Goli

    2015-09-01

    Full Text Available Distribution and optimum allocation of emergency resources are the most important tasks, which need to be accomplished during crisis. When a natural disaster such as earthquake, flood, etc. takes place, it is necessary to deliver rescue efforts as quickly as possible. Therefore, it is important to find optimum location and distribution of emergency relief resources. When a natural disaster occurs, it is not possible to reach some damaged areas. In this paper, location and multi-depot vehicle routing for emergency vehicles using tour coverage and random sampling is investigated. In this study, there is no need to visit all the places and some demand points receive their needs from the nearest possible location. The proposed study is implemented for some randomly generated numbers in different sizes. The preliminary results indicate that the proposed method was capable of reaching desirable solutions in reasonable amount of time.

  7. Area Plans for 'Factor 4': Trajectories to 2020, 2030 and 2050 in the Tours Conurbation

    International Nuclear Information System (INIS)

    Baratier, Jerome; Metais, Benedicte; Beauvais, Jean-Marie

    2013-01-01

    In 2009 a programme 'Re-thinking Society in a Post-carbon Society'- steered jointly by the Foresight Department of the French Ecology Ministry and the French Environment and Energy Management Agency (ADEME), was launched in France. It is still ongoing and aims to produce a final report in 2013. The idea of a transition towards a 'post-carbon' society includes four main objectives: reducing greenhouse gas emissions by 2050 to one quarter of what they were in 1990; near-autonomy with regard to carbon bon energies (petrol, gas, coal); an adequate capacity to adapt to climate change and, lastly, greater attention to situations of 'energy precariousness'. As part of the dossier Futuribles is devoting to this programme this month, this article represents a highly informative case study of the implementation of an area strategy for transition to 'factor 4' -that is to say, the reduction of greenhouse gas emissions by 2050 to one quarter of what they were in 1990. Baratier, Beauvais and Metais show how, largely on the basis of its 'Territorial Coherence Plan' (ScoT), the Tours conurbation has set about equipping itself, in a two- stage process (with target dates of 2020 and 2030), to achieve a post-carbon transition by 2050. They outline the key measures and objectives by sector and major energy consumption element, aiming to modify life - styles in the conurbation so as to make Tours a 'low carbon' city, a city of localities. Local public action, which is essential for success- fully achieving such a transition, cannot, of course, be effective without convergent efforts at all levels. Lastly, above and beyond this interconnectedness of public policies, the authors stress a number of questions that are equally crucial (in terms of timescales, economic investment, democracy etc.) in the implementation of a 'territorial factor 4'. (authors)

  8. Behavioural responses of dusky dolphin groups (Lagenorhynchus obscurus to tour vessels off Kaikoura, New Zealand.

    Directory of Open Access Journals (Sweden)

    David Lundquist

    Full Text Available BACKGROUND: Commercial viewing and swimming with dusky dolphins (Lagenorhynchus obscurus near Kaikoura, New Zealand began in the late 1980s and researchers have previously described changes in vocalisation, aerial behaviour, and group spacing in the presence of vessels. This study was conducted to assess the current effects that tourism has on the activity budget of dusky dolphins to provide wildlife managers with information for current decision-making and facilitate development of quantitative criteria for management of this industry in the future. METHODOLOGY/PRINCIPAL FINDINGS: First-order time discrete Markov chain models were used to assess changes in the behavioural state of dusky dolphin pods targeted by tour vessels. Log-linear analysis was conducted on behavioural state transitions to determine whether the likelihood of dolphins moving from one behavioural state to another changed based on natural and anthropogenic factors. The best-fitting model determined by Akaike Information Criteria values included season, time of day, and vessel presence within 300 m. Interactions with vessels reduced the proportion of time dolphins spent resting in spring and summer and increased time spent milling in all seasons except autumn. Dolphins spent more time socialising in spring and summer, when conception occurs and calves are born, and the proportion of time spent resting was highest in summer. Resting decreased and traveling increased in the afternoon. CONCLUSIONS/SIGNIFICANCE: Responses to tour vessel traffic are similar to those described for dusky dolphins elsewhere. Disturbance linked to vessels may interrupt social interactions, carry energetic costs, or otherwise affect individual fitness. Research is needed to determine if increased milling is a result of acoustic masking of communication due to vessel noise, and to establish levels at which changes to behavioural budgets of dusky dolphins are likely to cause long-term harm. Threshold

  9. IDENTIDAD URBANA Y EL TURISMO DE EVENTOS DEPORTIVOS: EL GRAND DEPART TOUR DE FRANCIA 2015

    Directory of Open Access Journals (Sweden)

    Juan Luis Paramio-Salcines

    2017-01-01

    Full Text Available Ciudades de todo tipo en la actual jerarquía urbana se afanan por adquirir una nueva identidad. En ese proceso de reinvención urbana, el turismo de eventos deportivos ha venido desarrollando una gran capacidad para generar diferentes impactos ‘tangibles’ e ‘intangibles’, como se argumenta en este artículo con el caso de la ciudad holandesa de Utrecht y la organización del Grand Depart Tour de Francia 2015 (GDTF. Si bien se ha analizado de manera amplia el uso estratégico del Tour de Francia por parte de numerosas ciudades en la última década desde la perspectiva de la oferta, este estudio exploratorio con un carácter marcadamente internacional que incluye nueve países, uno de los cuales es España, examina el GDTF 2015 desde la perspectiva de la demanda. En particular, estudia los factores clave que pueden facilitar o condicionar el deseo de viajar, previamente al propio evento, de ciudadanos españoles a Utrecht, para seguir dicho evento. Con el fin de valorar el grado de conocimiento de los principales atractivos de la ciudad, así como las principales motivaciones de estos ciudadanos españoles a la hora de viajar a Utrecht in situ, se han utilizado encuestas, un grupo de discusión y una revisión documental. El artículo concluye con los principales resultados que se derivan de las percepciones de los ciudadanos españoles de Utrecht y su relación con el GDTF 2015, además de las implicaciones prácticas de este caso.

  10. Konkurētspējas analīze medicīnas tūrisma attīstībai Latvijā.

    OpenAIRE

    Kadincovs, Artūrs

    2013-01-01

    Maģistra darba tēma ir „Konkurētspējas analīze medicīnas tūrisma attīstībai Latvijā”. Medicīnas tūrisms mūsdienās ir eksporta pakalpojums ar augstu pievienoto vērtību, kurš pozitīva scenārija rezultātā nes lielus ienākumus uzņēmējdarbības videi un valsts ekonomikai un rada labi apmaksātu speciālistu pieprasījumu. Pēc autora domām, medicīnas tūrisma attīstībai Latvijā ir perspektīvs scenārijs, jo Latvijai ir visss nepieciešamais, gan kvalificēts darbaspēks, gan resursi, turklāt pietiekoši ...

  11. „Honda” korporācijas konkurētspēja Japānas un pasaules auto industrijas tirgū

    OpenAIRE

    Rubina, Jeļena

    2010-01-01

    Bakalaura darbs „„Honda” korporācijas konkurētspēja Japānas un pasaules auto industrijas tirgū” ir veltīts „Honda” korporācijas izpētei, balstoties uz vairākiem faktoriem, kuri ietekmējuši tās panākumus Japānas un pasaules auto industrijā. To skaitā ir korporācijas vēsture un pieredze moto industrijā, kas sekmējusi korporācijas stratēģijas izveidi, tehnoloģiju attīstīšana, kuru veic speciāla korporācijas filiāle, un to pielietošana auto būvniecībā, tai skaitā arī hibrīdauto un sacīkšu auto...

  12. Sistem Informasi Manajemen Rantai Pasok Pariwisata Untuk Pembuatan Produk Wisata Pada Agen Tour dan Travel dengan Analisis Swot dan Metode Analytic Network Process

    Directory of Open Access Journals (Sweden)

    Dwi Mustika Kusumawardani

    2016-12-01

    Full Text Available The development of services company in tourism is increasing. Therefore each tour & travel agent should be able to improve the quality of attractive and competitive products. This research builds a system analysis of supply chain management in the manufacturing of tour packages with SWOT analysis and Analytic Network Process (ANP. SWOT analysis is one way to decide marketing strategy for the company to able to face global competition. In this study, a SWOT analysis is used to select the best suppliers in tourism sector. Suppliers include: hotels, restaurants, attractions and accommodations. Combination of the best suppliers used as in one product of tour package. While the method of Analytic Network Process is used to rank the tour package has been obtained previously. In addition, this method is applied because it can provide information about the most influential of criteria in making tour package. This method conducted by looking at dependency relationship between among criteria. Then give them weight among criteria, sub-criteria and alternatives. The criteria used in the method of Analytic Network Process are: product, price, place and promotion. The results obtained from this research is the system analysis of supply chain management of tourism which capable of producing an attractive and competitive tour packages form of tour packages 1 with a value of 0.53. In addition, this information system provides information that the most influential criteria in making tour package is the product criteria with a value of 0.30. The next criterion which affects the making of attractive and competitive tour packages is price of criteria with a value of 0.28.

  13. Optimization and Optimal Control

    CERN Document Server

    Chinchuluun, Altannar; Enkhbat, Rentsen; Tseveendorj, Ider

    2010-01-01

    During the last four decades there has been a remarkable development in optimization and optimal control. Due to its wide variety of applications, many scientists and researchers have paid attention to fields of optimization and optimal control. A huge number of new theoretical, algorithmic, and computational results have been observed in the last few years. This book gives the latest advances, and due to the rapid development of these fields, there are no other recent publications on the same topics. Key features: Provides a collection of selected contributions giving a state-of-the-art accou

  14. Optimally Stopped Optimization

    Science.gov (United States)

    Vinci, Walter; Lidar, Daniel

    We combine the fields of heuristic optimization and optimal stopping. We propose a strategy for benchmarking randomized optimization algorithms that minimizes the expected total cost for obtaining a good solution with an optimal number of calls to the solver. To do so, rather than letting the objective function alone define a cost to be minimized, we introduce a further cost-per-call of the algorithm. We show that this problem can be formulated using optimal stopping theory. The expected cost is a flexible figure of merit for benchmarking probabilistic solvers that can be computed when the optimal solution is not known, and that avoids the biases and arbitrariness that affect other measures. The optimal stopping formulation of benchmarking directly leads to a real-time, optimal-utilization strategy for probabilistic optimizers with practical impact. We apply our formulation to benchmark the performance of a D-Wave 2X quantum annealer and the HFS solver, a specialized classical heuristic algorithm designed for low tree-width graphs. On a set of frustrated-loop instances with planted solutions defined on up to N = 1098 variables, the D-Wave device is between one to two orders of magnitude faster than the HFS solver.

  15. QUANTUM INSPIRED PARTICLE SWARM COMBINED WITH LIN-KERNIGHAN-HELSGAUN METHOD TO THE TRAVELING SALESMAN PROBLEM

    Directory of Open Access Journals (Sweden)

    Bruno Avila Leal de Meirelles Herrera

    2015-12-01

    Full Text Available ABSTRACT The Traveling Salesman Problem (TSP is one of the most well-known and studied problems of Operations Research field, more specifically, in the Combinatorial Optimization field. As the TSP is a NP (Non-Deterministic Polynomial time-hard problem, there are several heuristic methods which have been proposed for the past decades in the attempt to solve it the best possible way. The aim of this work is to introduce and to evaluate the performance of some approaches for achieving optimal solution considering some symmetrical and asymmetrical TSP instances, which were taken from the Traveling Salesman Problem Library (TSPLIB. The analyzed approaches were divided into three methods: (i Lin-Kernighan-Helsgaun (LKH algorithm; (ii LKH with initial tour based on uniform distribution; and (iii an hybrid proposal combining Particle Swarm Optimization (PSO with quantum inspired behavior and LKH for local search procedure. The tested algorithms presented promising results in terms of computational cost and solution quality.

  16. [Tour operator liability in health protection for not informing travellers about health risks they could be exposed].

    Science.gov (United States)

    Macrì, P G

    2009-01-01

    Consumer-tourist is considered the weaker bargaining party in an "all included" travel contract, compared with tour organizer and tour vendor. That's why Statute Act protecting consumer's rights provides a specific discipline concerning this particular sector In front of widening of warrants for travellers, obligations for organizer and seller of the travel have been increased, and include now specific duty to inform travellers as well. According to the law such duties of information are consistent with travel contract performance itself. In such way, failing to inform client constitutes a breach of contract liable not only in the field of civil responsibility; the subject liable with such an omission may face criminal prosecution as well. More specifically we are in front of a breach of contract by the tour organizer who will respond of all damages concerned with such a breach. Damages will concern not only the price of the travel package, but also other damages connected with the illness suffered by traveller: compensation for spoiled holidays, biological damages, patrimonial damages (these last ones could include for instance expenses for medical treatments, just to quote the more likely one). In other words, tour organizer has to grant general organization of the tour which has to take place as specified on travel brochure, but traveller have to be provided also with any information, concerning documents necessary for the travel, whether passport or visa are needed or not, vaccinations peremptory or optional. It will be very difficult for tour operator be exempted from liability for damages if traveller hasn't been informed of health risks; the only possibility consists in managing to demonstrate that the obligation hasn't been compelled due to reason for which the operator couldn't be held responsible. Besides as we have already mentioned before, criminal relevance of such omission of information couldn't be excluded. In fact, it's true that such omission

  17. Study tours. Come and get a whole set of ideas in 14 european towns and cities; Study tours. Venez faire le plein d'idees neuves dans 14 villes d'Europes

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    The European towns and cities which have been selected by Energie-Cites are all members of Energie-Cites and have for many years been involved in innovative projects in the field of energy (energy efficiency, renewable and distributed energy). To acquire a better understanding of how these projects came into being and, why not, use them as a source of inspiration for a municipality? During two days, Energie-Cites proposes to take deciders to the city of their choice. Tours include site visits as well as meetings with local political and technical stakeholders. These study tours are specifically intended for elected representatives and municipal officers in charge of energy matters, Local Agenda 21, town planning and environmental issues (30 persons as a max. per visit). A 14 typical visit is provided for each town or city, in this document. (A.L.B.)

  18. "La Tour de Soleil" - Alvar Aalto võistlusprojekt Pärnu supelasutuse ehituseks = La Tour de Soleil - Alvar Aalton kilpailuehdotus Pärnun kylpylärakkenusta varten / Katariina Pakoma

    Index Scriptorium Estoniae

    Pakoma, Katariina

    2004-01-01

    Soome arhitektist Alvar Aaltost. Pärnu supelasutuse 1925. a. arhitektuurivõistlusest. Soomest oli võistlusele saadetud 20 tööd, teiste hulgas osales soome juhtiv arhitekt Uno Ullberg, noorema põlvkonna arhitektidest Hilding Ekelund, Georg Henriksson. Alvar Aalto võistlustööst "La Tour de Soleil". A. Aalto ja põhjamaine klassitsism. Rööptekst joonealustes märkustes

  19. Particle Swarm Optimization applied to combinatorial problem aiming the fuel recharge problem solution in a nuclear reactor; Particle swarm optimization aplicado ao problema combinatorio com vistas a solucao do problema de recarga em um reator nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Meneses, Anderson Alvarenga de Moura; Schirru, Roberto [Universidade Federal, Rio de Janeiro, RJ (Brazil). Coordenacao dos Programas de Pos-graduacao de Engenharia. Programa de Engenharia Nuclear]. E-mail: ameneses@con.ufrj.br; schirru@lmp.ufrj.br

    2005-07-01

    This work focuses on the usage the Artificial Intelligence technique Particle Swarm Optimization (PSO) to optimize the fuel recharge at a nuclear reactor. This is a combinatorial problem, in which the search of the best feasible solution is done by minimizing a specific objective function. However, in this first moment it is possible to compare the fuel recharge problem with the Traveling Salesman Problem (TSP), since both of them are combinatorial, with one advantage: the evaluation of the TSP objective function is much more simple. Thus, the proposed methods have been applied to two TSPs: Oliver 30 and Rykel 48. In 1995, KENNEDY and EBERHART presented the PSO technique to optimize non-linear continued functions. Recently some PSO models for discrete search spaces have been developed for combinatorial optimization. Although all of them having different formulation from the ones presented here. In this paper, we use the PSO theory associated with to the Random Keys (RK)model, used in some optimizations with Genetic Algorithms. The Particle Swarm Optimization with Random Keys (PSORK) results from this association, which combines PSO and RK. The adaptations and changings in the PSO aim to allow the usage of the PSO at the nuclear fuel recharge. This work shows the PSORK being applied to the proposed combinatorial problem and the obtained results. (author)

  20. The Main-belt Asteroid and NEO Tour with Imaging and Spectroscopy (MANTIS)

    Science.gov (United States)

    Rivkin, A.; Cohen, B. A.; Barnouin, O. S.; Chabot, N. L.; Ernst, C. M.; Klima, R. L.; Helbert, J.; Sternovsky, Z.

    2015-12-01

    The asteroids preserve information from the earliest times in solar system history, with compositions in the population reflecting the material in the solar nebula and experiencing a wide range of temperatures. Today they experience ongoing processes, some of which are shared with larger bodies but some of which are unique to their size regime. They are critical to humanity's future as potential threats, resource sites, and targets for human visitation. However, over twenty years since the first spacecraft encounters with asteroids, they remain poorly understood. The mission we propose here, the Main-belt Asteroid and NEO Tour with Imaging and Spectroscopy (MANTIS), explores the diversity of asteroids to understand our solar system's past history, its present processes, and future opportunities and hazards. MANTIS addresses many of NASA's highest priorities as laid out in its 2014 Science Plan and provides additional benefit to the Planetary Defense and Human Exploration communities via a low-risk, cost-effective tour of the near-Earth and inner asteroid belt. MANTIS visits the materials that witnessed solar system formation and its earliest history, addressing the NASA goal of exploring and observing the objects in the solar system to understand how they formed and evolve. MANTIS measures OH, water, and organic materials via several complementary techniques, visiting and sampling objects known to have hydrated minerals and addressing the NASA goal of improving our understanding of the origin and evolution of life on Earth. MANTIS studies the geology and geophysics of nine diverse asteroids, with compositions ranging from water-rich to metallic, representatives of both binary and non-binary asteroids, and sizes covering over two orders of magnitude, providing unique information about the chemical and physical processes shaping the asteroids, addressing the NASA goal of advancing the understanding of how the chemical and physical processes in our solar system

  1. Particle Swarm Optimization applied to combinatorial problem aiming the fuel recharge problem solution in a nuclear reactor

    International Nuclear Information System (INIS)

    Meneses, Anderson Alvarenga de Moura; Schirru, Roberto

    2005-01-01

    This work focuses on the usage the Artificial Intelligence technique Particle Swarm Optimization (PSO) to optimize the fuel recharge at a nuclear reactor. This is a combinatorial problem, in which the search of the best feasible solution is done by minimizing a specific objective function. However, in this first moment it is possible to compare the fuel recharge problem with the Traveling Salesman Problem (TSP), since both of them are combinatorial, with one advantage: the evaluation of the TSP objective function is much more simple. Thus, the proposed methods have been applied to two TSPs: Oliver 30 and Rykel 48. In 1995, KENNEDY and EBERHART presented the PSO technique to optimize non-linear continued functions. Recently some PSO models for discrete search spaces have been developed for combinatorial optimization. Although all of them having different formulation from the ones presented here. In this paper, we use the PSO theory associated with to the Random Keys (RK)model, used in some optimizations with Genetic Algorithms. The Particle Swarm Optimization with Random Keys (PSORK) results from this association, which combines PSO and RK. The adaptations and changings in the PSO aim to allow the usage of the PSO at the nuclear fuel recharge. This work shows the PSORK being applied to the proposed combinatorial problem and the obtained results. (author)

  2. The Effects of Land Use Patterns on Tour Type Choice. The Application of a Hybrid Choice Model

    DEFF Research Database (Denmark)

    de Abreu e Silva, João; Sottile, Eleonora; Cherchi, Elisabetta

    2014-01-01

    to travel. Workers who reside in more central, mixed and traditional urban spaces tend to have a higher propensity to travel. Workers who live in more diverse areas have a higher probability of engaging in more complex work related tours. Working in more suburban areas reduces the probability of engaging......The relations between travel behavior and land use patterns have been the object of intensive research in the last two decades. Due to their immediate policy implications, mode choice and vehicle miles of travel (VMT) have been the main focus of attention. Other relevant dimensions, like trip...... of the latent propensity to travel in the discrete choice among types of tours. This model is applied to a travel diary of workers collected in the Lisbon Metropolitan Area in 2009. Different model specifications were built, testing the inclusion of purportedly built land use factors, which have the advantage...

  3. Educating and training north american travel agents and tour operators with webinars: the case of Switzerland Tourism North America

    OpenAIRE

    Kurt, Victoria; Salamin, Anne-Dominique

    2015-01-01

    Switzerland Tourism provides reliable, informative, high quality and long-term contacts to key accounts such as Travel Agents and Tour Operators in North America with the aim of boosting Switzerland’s presence in the market. The Trade Department is using various online tools such as e-learning platforms, a social media group and Webinars to educate and train the travel professionals. Since 2003, participants to Webinars have increased smoothly; therefore the Company would like to know if this...

  4. Using a Web-Based Resource to Prepare Students for Fieldwork: Evaluating the Dark Peak Virtual Tour

    Science.gov (United States)

    McMorrow, Julia

    2005-01-01

    This paper reports on development of a Dark Peak website and its use to prepare first-year geography students for a one-day physical geography field course in the south Pennines. The Virtual Tour (VT) component of the website is the main focus of this paper. Pre- and post-fieldwork evaluations of the first version of the VT by 195 students are…

  5. Ecotourism, sustainable development, and conservation education: Development of a tour guide training program in Tortuguero, Costa Rica

    Science.gov (United States)

    Jacobson, Susan K.; Robles, Rafael

    1992-11-01

    A tour guide training program was developed for rural communities near Costa Rica's Tortuguero National Park to respond to the impacts of the 24-fold increase in park visitation in the past decade, to involve local communities in resource management, and to provide regional environmental education. The development of the training course involved a survey of scientists and park managers to ascertain resource management needs, priorities for information to be disseminated, and impacts of tourism on the resource base. Current and potential tour guides were surveyed to identify their information needs, solicit their input in the training program, and to determine their knowledge and skills. Written questionnaires were developed and given to 400 tourists to determine their activities and environmental information needs, and hotel owners were censused to examine the economic feasibility of a local guide program. A pilot training course and guide program involving 12 Tortuguero residents demonstrated that a tour guide program: (1) helped mitigate negative tourism impacts on Tortuguero National Park's natural resources, particularly by regulating tourists on the park's 35-km beach used for nesting by endangered sea turtles; (2) provided environmental education to an important segment of the local community not traditionally reached through school or government development projects; (3) provided environmental information to tourists, thus enhancing their visit; and (4) provided local economic benefits through lucrative part-time employment, thereby allowing local people to participate more fully in the tourism system. An extended training course is being planned to provide further environmental education programming and to increase year-round employment opportunities for the tour guides.

  6. Blind MuseumTourer: A System for Self-Guided Tours in Museums and Blind Indoor Navigation

    OpenAIRE

    Apostolos Meliones; Demetrios Sampson

    2018-01-01

    Notably valuable efforts have focused on helping people with special needs. In this work, we build upon the experience from the BlindHelper smartphone outdoor pedestrian navigation app and present Blind MuseumTourer, a system for indoor interactive autonomous navigation for blind and visually impaired persons and groups (e.g., pupils), which has primarily addressed blind or visually impaired (BVI) accessibility and self-guided tours in museums. A pilot prototype has been developed and is curr...

  7. Relationship model among sport event image, destination image, and tourist satisfaction of Tour de Singkarak in West Sumatera

    Directory of Open Access Journals (Sweden)

    Ratni Prima Lita

    2015-06-01

    Full Text Available Sport events Tour de Singkarak (TDS can increase tourist arrivals to West Sumatera. At least at the time of execution, the majority of participants and team supporters (sports tourist brings the families. Although there are claims about the arrival of tourists, it requires to see the impact of sports events TDS and comprehensive long-term basis to the West Sumatera image as a tourist destination (destination image and its impact on tourist satisfaction. This study re-conceptualizes the interconnec-tedness among sport event image, tourist destination image, perception and the effect on tourists satisfaction. The investigation on this interconnection is expected to reveal empirically tested model. As an explanatory in nature, this study uses explanatory survey and cross sectional data. In total of 100 spectators of Tour de Singkarak in West Sumatera, they got involved in survey and they were taken by convenience sam-pling technique. Analysis of this data was done by using variance based structural equation modeling. It was found that sport event image and destination image signifi-cantly affect the satisfaction of spectators of Tour de Singkarak.

  8. The use of e-business in Serbian travel agencies: Development of the EBusTour model

    Directory of Open Access Journals (Sweden)

    Mišković Ivana

    2016-01-01

    Full Text Available Conducting business by using the internet has become an everyday occurrence in all spheres of economy, as well as in the tourism sector. There is an increasing number of agencies in the world that conduct their business almost completely on-line. The aim of this research was to examine what characterizes the process of implementation of electronic business with tourist agencies in Serbia on the sample of 65 companies, and whether it differs depending on certain business characteristics. For that purpose, EBusTour model was developed that consists of 14 items grouped into four categories: online communication, online promotion, impact on sales and working hours reduction vs. sales improvement. As far as tourist agencies in Serbia are concerned, the results of the application of EBusTour model show that the most common activity in this field is basic online promotion (website implementation, followed by effects on sales. The paper also investigates whether there are differences in e-business implementation in relation to the characteristics such as: years in business, the type of licence (tour operator or sales agent and the type of market (incoming, outgoing or combined.

  9. Design of Backpack to Aid Elderly for the Mazu Touring Procession in Taiwan

    Science.gov (United States)

    Chao, F. L.; Huang, Y. C.; Su, J. Y.; Sun, C. L.; Chen, C. C.

    2017-09-01

    The Dajia Mazu Touring Procession is a 9-day long religious event held annually. However, for the elderly participants, it is a big burden especially in regards to physical strength. The goal of designing backpack is to reduce the physiological stress of elderly during the procession. Firstly, physical parameters were measured to explore the dimension parameters by testing. The height of the chair is different from that of the kneeling pad; a smooth curve was chosen to coordinate the two as the main outline of the backpack. Secondly, material selections based on following limits were considered: (1) acceptable weight and size, (2) intermediate price and (3) a design that is fitting to the Dajia event. The material and structural strength were evaluated for wood, bamboo, stainless steel. Two design concept were proposed, wood is selected for construction and testing by users. The texture of the backpack is Rush grass, it was built successfully to cover the backpack’s external surface to meet local culture features.

  10. Moundsville Penitentiary Reconsidered: Second Thoughts on Hyperreality at a Small Town Prison Tour

    Directory of Open Access Journals (Sweden)

    Allen Mendenhall

    2010-02-01

    Full Text Available In 2007, I toured Moundsville Penitentiary, a tourist spectacle that was once—and fairly recently—a working prison. I wrote about the experience as would a journalist, except that my working paradigm was the postmodern theory of hyperreality, which Jean Baudrillard used to describe the complex tensions between reality and illusion. A term of semiotics, hyperreality refers to the disappearance of the referent and its subsequent, oft-replicated simulation. It almost always involves strategically controlled images that distort and conceal true meaning. The International Journal of Baudrillard Studies published my essay in January 2009. Shortly thereafter, many of my libertarian friends and colleagues wrote to ask for clarification or to express their disagreements. In what follows, whether I’m describing hyperreality or speculating about the horror-themed attractions at Moundsville Penitentiary, my principal concern is laying the libertarian foundation for my argument. I do not mean to defend my theories so much as explain them; nor do I insist that my cultural criticism is somehow “the” right way. I simply hope to fill a critical vacuum and to generate conversation not only about the condition of the American prison system writ large, but also about state-run tourist attractions that glorify the history of the sovereign at the expense of real knowledge about human suffering.

  11. Genre differentiation in ”A guided Tour through the Museum of Communism” by Slavenka Draculic

    Directory of Open Access Journals (Sweden)

    Jakov Sabljić

    2013-06-01

    Full Text Available On the 20th anniversary of the fall of the Berlin Wall, a Croatian novelist Slavenka Drakulic simultaneously in several countries published a collection of essays titled A Guided Tour through the Museum of Communism. The collection consists of eight stories narrated by animals: a mole, a mouse, a dog, a cat, a raven, a parrot, a pig and a bear. The animals talk about neuralgic issues of Communism in former Eastern European countries (Eastern Germany, Czechoslovakia, Poland, Rumania, Albania, Yugoslavia, Hungary and Bulgaria. The genre differentiation is based on determining postmodern variations of basic genre conventions in the process of creating a piece of literature. Fable variations are determined by analyzing the relationship between a fable and other genre forms, such as, an essay, a novella, a legend, a myth. Next to genre differentiation of a literary structure, one can also observe the differentiation of its role that has been conditioned by today’s cultural memory. In that manner, mythologized persons, objects and features of Communism are analyzed as universal symbols of a message, as well as elements of a satiric play. This paper will determine in which ways the above mentioned variations enrich the existent genre forms.

  12. NASA Pathways Co-op Tour Johnson Space Center Fall 2013

    Science.gov (United States)

    Masood, Amir; Osborne-Lee, Irwin W.

    2013-01-01

    This report outlines the tasks and objectives completed during a co-operative education tour with National Aeronautics and Space Association (NASA) at the Johnson Space Center in Houston, Texas. I worked for the Attitude & Pointing group of the Flight Dynamics Division within the Mission Operations Directorate at Johnson Space Center. NASA's primary mission is to support and expand the various ongoing space exploration programs and any research and development activities associated with it. My primary project required me to develop and a SharePoint web application for my group. My secondary objective was to become familiar with the role of my group which was primarily to provide spacecraft attitude and line of sight determination, including Tracking and Data Relay Satellite (TDRS) communications coverage for various NASA, International, and commercial partner spacecraft. My projects required me to become acquainted with different software systems, fundamentals of aerospace engineering, project management, and develop essential interpersonal communication skills. Overall, I accomplished multiple goals which included laying the foundations for an updated SharePoint which will allow for an organized platform to communicate and share data for group members and external partners. I also successfully learned about the operations of the Attitude & Pointing Group and how it contributes to the Missions Operations Directorate and NASA's Space Program as a whole

  13. Atom land guided tour through the strange (and impossibly small) world of particle physics

    CERN Document Server

    Butterworth, Jon

    2018-01-01

    For fans of Seven Brief Lessons on Physics and Astrophysics for People in a Hurry: a richly conjured world, in map and metaphor, of particle physics. Atom Land brings the impossibly small world of particle physics to life, taking readers on a guided journey through the subatomic world. Readers will sail the subatomic seas in search of electron ports, boson continents, and hadron islands. The sea itself is the quantum field, complete with quantum waves. Beware dark energy and extra dimensions, embodied by fantastical sea creatures prowling the far edges of the known world. Your tour guide through this whimsical—and highly instructive— world is Jon Butterworth, leading physicist at CERN (the epicenter of today’s greatest findings in physics). Over a series of journeys, he shows how everything fits together, and how a grasp of particle physics is key to unlocking a deeper understanding of many of the most profound mysteries—and science’s possible answers—in the known universe.

  14. Spherical photography and virtual tours for presenting crime scenes and forensic evidence in new zealand courtrooms.

    Science.gov (United States)

    Tung, Nicole D; Barr, Jason; Sheppard, Dion J; Elliot, Douglas A; Tottey, Leah S; Walsh, Kevan A J

    2015-05-01

    The delivery of forensic science evidence in a clear and understandable manner is an important aspect of a forensic scientist's role during expert witness delivery in a courtroom trial. This article describes an Integrated Evidence Platform (IEP) system based on spherical photography which allows the audience to view the crime scene via a virtual tour and view the forensic scientist's evidence and results in context. Equipment and software programmes used in the creation of the IEP include a Nikon DSLR camera, a Seitz Roundshot VR Drive, PTGui Pro, and Tourweaver Professional Edition. The IEP enables a clear visualization of the crime scene, with embedded information such as photographs of items of interest, complex forensic evidence, the results of laboratory analyses, and scientific opinion evidence presented in context. The IEP has resulted in significant improvements to the pretrial disclosure of forensic results, enhanced the delivery of evidence in court, and improved the jury's understanding of the spatial relationship between results. © 2015 American Academy of Forensic Sciences.

  15. March of the Living, a Holocaust Educational Tour: An Assessment of Anxiety and Depression.

    Science.gov (United States)

    Nager, Alan L; Pham, Phung; Grajower, Sarah N; Gold, Jeffrey I

    2016-06-01

    March of the Living (MOTL) is a 2-week international educational tour for high school seniors to learn about the Holocaust by visiting concentration/deaths camps and other Jewish historical sites in Poland, culminating in a week-long excursion in Israel. Although the trip is primarily educational, there is recent research evidence to suggest that attendees may suffer from a variety of mental health sequelae. To determine symptoms of anxiety and depression, 196 Los Angeles delegation participants voluntarily completed the State-Trait Anxiety Inventory, composed of a trait anxiety scale (i.e., STAI-T) and a state anxiety scale (i.e., STAI-S), and the Center for Epidemiologic Studies Depression Scale (CES-D). Pre-MOTL, students completed an initial background questionnaire along with the STAI-T, STAI-S, and the CES-D. At end-Poland and end-Israel, the STAI-S and CES-D were administered again. Results demonstrated that depression scores increased during end-Poland and returned to baseline; however, anxiety scores mildly increased end-Poland and rose slightly more and persisted through end-Israel.

  16. [Stoma use in the general surgery service of CHU Gabriel Touré].

    Science.gov (United States)

    Traore, A; Diakite, I; Togo, A; Dembele, B T; Kante, L; Coulibaly, Y; Keita, M; Diango, D M; Diallo, A; Diallo, G

    2010-01-01

    Were to determine the frequency, to describe the clinical and therapeutic aspects digestive stoma. It was about six months an exploratory study from January 1st to June 30th, 2008 in the department of surgery general of the CHU Gabriel Touré. Were included in this study all the patients carrying a enter stoma or a colostomy, old of more than 15 ans. The digestive dents, the other types of stoma and the patients old of less than 15 years, were excluded. The results were analyzed by the software Epi information version 6.4 Fr, the tests of Khi 2 and Student with a threshold of significance for P stomiale 4 cas (12.5%), the suppuration peristomial 3 cas (9.4%), the releasing of Stoma 3 cas (9.4%), the retraction of the stoma 3 cas (9.4%),the psychological disorders 3 cases (9.4%), the hemorrhage 2 cas (6.3), necroses peristomial 2 cas (3.1%), septic shock 2 cas (6.3%), and 1 cas (3.1%) of evisceration, obstruction of the bowels, shock hypovolemic. The intermediate duration of hospitalization was of 37,5 jours with a standard deviation = 13.58 and extremes varying between 02-73 days. Death rate was of 9.4%. The assumption of responsibility of the stomies is difficult in the absence of stomatherapeutes, and of the high cost of the parenteral nutrition in our context .

  17. Report on the first visiting tour in fiscal 1999; 1999 nendo daiikkai kengakukai hokoku

    Energy Technology Data Exchange (ETDEWEB)

    Matsunuma, T. [Mechanical Engineering Lab., Tokyo (Japan)

    1999-09-20

    This paper reports the first visiting tour in 1999 held by the Japan Gas Turbine Society. The visit was made to the Second Technical School of the Maritime Self Defense Force in Yokosuka. The school was established as the Torpedo Training School of the Navy in 1989, and now implementing education mainly on engines, emergency measures, information, and foreign languages as one of the four currently operating technical schools. The school gives the education to 1000 students every year. The gas turbine drills included training on replacement of turbine auxiliary engines, operation and adjustment of the M1A gas turbine engine, maneuvering of gas turbine engines, operation of full-size engines, and servicing of a diesel engine. The training for electrical and emergency actions included training on a lathe, a milling machine, woodworking, and gas welding to deal with unexpected happenings on ocean. A visit was made to the general purpose escort ship having a helicopter on board, 'Harusame'. The vessel has a total length of 151 m, a width of 17.4 m and a height of 47 m, boarding 166 men. It is mounted with four gas turbine engines as the main engines (with a total output of 60,000 horsepower), and three small gas turbine engines and one diesel engine as the auxiliary engines. The engine room is said sufficiently monitored only by video cameras in normal operation. (NEDO)

  18. Mobile Mapping of Sporting Event Spectators Using Bluetooth Sensors: Tour of Flanders 2011

    Directory of Open Access Journals (Sweden)

    Frederik van Bossche

    2012-10-01

    Full Text Available Accurate spatiotemporal information on crowds is a necessity for a better management in general and for the mitigation of potential security risks. The large numbers of individuals involved and their mobility, however, make generation of this information non-trivial. This paper proposes a novel methodology to estimate and map crowd sizes using mobile Bluetooth sensors and examines to what extent this methodology represents a valuable alternative to existing traditional crowd density estimation methods. The proposed methodology is applied in a unique case study that uses Bluetooth technology for the mobile mapping of spectators of the Tour of Flanders 2011 road cycling race. The locations of nearly 16,000 cell phones of spectators along the race course were registered and detailed views of the spatiotemporal distribution of the crowd were generated. Comparison with visual head counts from camera footage delivered a detection ratio of 13.0 ± 2.3%, making it possible to estimate the crowd size. To our knowledge, this is the first study that uses mobile Bluetooth sensors to count and map a crowd over space and time.

  19. Gems of combinatorial optimization and graph algorithms

    CERN Document Server

    Skutella, Martin; Stiller, Sebastian; Wagner, Dorothea

    2015-01-01

    Are you looking for new lectures for your course on algorithms, combinatorial optimization, or algorithmic game theory?  Maybe you need a convenient source of relevant, current topics for a graduate student or advanced undergraduate student seminar?  Or perhaps you just want an enjoyable look at some beautiful mathematical and algorithmic results, ideas, proofs, concepts, and techniques in discrete mathematics and theoretical computer science?   Gems of Combinatorial Optimization and Graph Algorithms is a handpicked collection of up-to-date articles, carefully prepared by a select group of international experts, who have contributed some of their most mathematically or algorithmically elegant ideas.  Topics include longest tours and Steiner trees in geometric spaces, cartograms, resource buying games, congestion games, selfish routing, revenue equivalence and shortest paths, scheduling, linear structures in graphs, contraction hierarchies, budgeted matching problems, and motifs in networks.   This ...

  20. 2D and 3D Traveling Salesman Problem

    Science.gov (United States)

    Haxhimusa, Yll; Carpenter, Edward; Catrambone, Joseph; Foldes, David; Stefanov, Emil; Arns, Laura; Pizlo, Zygmunt

    2011-01-01

    When a two-dimensional (2D) traveling salesman problem (TSP) is presented on a computer screen, human subjects can produce near-optimal tours in linear time. In this study we tested human performance on a real and virtual floor, as well as in a three-dimensional (3D) virtual space. Human performance on the real floor is as good as that on a…

  1. Measurement of activity concentrations of {sup 40}K, 2{sup 32T}h and {sup 238}U in TSP aerosols and the associated inhalation annual effective radiation dose to the public in Gosan site, Jeju

    Energy Technology Data Exchange (ETDEWEB)

    Han, Chung Hun; Park, Youn Hyun; Park, Jae Woo [Jeju National University, Jeju (Korea, Republic of)

    2016-10-15

    Gamma radiation emitted from naturally occurring radioisotopes, such as 40K and the radionuclides from the {sup 232}Th and {sup 238}U series and their decay products, which exist at trace levels in all ground formations, represents the main external source of irradiation to the human body. The objective of the current study is to determine the activity concentrations of 40K, {sup 232}Th and {sup 238}U in airborne TSP and the associated internal radiation dose to the public due to inhalation in Gosan site, Jeju Island, Korea. The atmospheric total suspended particulates (TSP) aerosols were collected at Gosan site of Jeju Island, which is one of the background sites of Korea, during January to April 2013. This study analyzed using ICP-DRC-MS the concentrations of potassium, uranium and thorium, and evaluated the annual effective dose by breathing from the results. The correlations between the studied natural isotopes is a good positive correlation between {sup 232}Th and {sup 238}U, supporting the conclusion that they originated from the same source, mostly the crust. The backward trajectory analysis has confirmed that the 40K, {sup 238}U and {sup 232}Th are delivered as the air masses have moved from the China continent. The inhalation annual effective radiation dose (default mode F) to the public due to natural isotopes of the airborne TSP was in the range 16.195 - 77.051 nSv/y, depending on the age group. Jeju Island with less pollution source and low population density is also one of the best places as a background area in Asia.

  2. Determination of trace metal concentration in compost, DAP, and TSP fertilizers by neutron activation analysis (NAA) and insights from density functional theory calculations.

    Science.gov (United States)

    Rahman, Md Sajjadur; Hossain, Syed Mohammod; Rahman, Mir Tamzid; Halim, Mohammad A; Ishtiak, Mohammad Niaz; Kabir, Mahbub

    2017-11-08

    Leaching of toxic metals from fertilizers is a growing concern in an agricultural country like Bangladesh due to the serious consequences in health and food chain. Fertilizers used in farming fields and nurseries (plant sales outlet) in the mid-southern part of Bangladesh were collected for the determination of toxic metals. This study employed the neutron activation method and a relative standardization approach. Three standard/certified reference materials, namely NIST coal fly ash 1633b, IAEA-Soil-7, and IAEA-SL-1 (lake sediment), were considered for elemental quantification. Concentration of As (2.63-16.73 mg/kg), Cr (40.93-261.77 mg/kg), Sb (0.47-63.58 mg/kg), Th (1.44-19.16 mg/kg), and U (1.90-209.41 mg/kg) were determined in fertilizers. High concentrations of Cr, Sb, and U were detected in some compost and phosphate fertilizers (TSP and diammonium phosphate (DAP)) in comparison with the IAEA/European market standard and other studies. Quantum mechanical calculations were performed to understand the molecular level interaction of CrO 3 , Sb 2 O 3 , and AsO 3 , with DAP by employing density functional theory with the B3LYP/SDD level of theory. Our results indicated that CrO 3 and Sb 2 O 3 have strong binding affinity with DAP compared to AsO 3 , which supports the experimental results. These compounds attached to the phosphate group through covalent-like bonding with oxygen. The frontier molecular orbital calculation indicated that HOMO-LUMO gap of the AsO 3 -DAP (5.46 eV) and Sb 2 O 3 -DAP (6.48 eV) complexes are relatively lower than the CrO 3 -DAP, which indicates that As and Sb oxides are chemically more prone to attach with the phosphate group of DAP fertilizer.

  3. Household air pollution and personal inhalation exposure to particles (TSP/PM2.5/PM1.0/PM0.25) in rural Shanxi, North China.

    Science.gov (United States)

    Huang, Ye; Du, Wei; Chen, Yuanchen; Shen, Guofeng; Su, Shu; Lin, Nan; Shen, Huizhong; Zhu, Dan; Yuan, Chenyi; Duan, Yonghong; Liu, Junfeng; Li, Bengang; Tao, Shu

    2017-12-01

    Personal exposure to size-segregated particles among rural residents in Shanxi, China in summer, 2011 were investigated using portable carried samplers (N = 84). Household air pollution was simultaneously studied using stationary samplers in nine homes. Information on household fuel types, cooking activity, smoking behavior, kitchen ventilation conditions etc., were also collected and discussed. The study found that even in the summer period, the daily average concentrations of PM 2.5 and PM 1.0 in the kitchen were as high as 376 ± 573 and 288 ± 397 μg/m 3 (N = 6), that were nearly 3 times of 114 ± 81 and 97 ± 77 μg/m 3 in the bedroom (N = 8), and significantly higher than those of 64 ± 28 and 47 ± 21 μg/m 3 in the outdoor air (N = 6). The personal daily exposure to PM 2.5 and PM 1.0 were 98 ± 52 and 77 ± 47 μg/m 3 , respectively, that were lower than the concentrations in the kitchen but higher than the outdoor levels. The mass fractions of PM 2.5 in TSP were 90%, 72%, 65% and 68% on average in the kitchen, bedroom, outdoor air and personal inhalation exposure, respectively, and moreover, a majority of particles in PM 2.5 had diameters less than 1.0 μm. Calculated time-weighted average exposure based on indoor and outdoor air concentrations and time spent indoor and outdoor were positively correlated but, was ∼33% lower than the directly measured exposure. The daily exposure among those burning traditional solid fuels could be lower by ∼41% if the kitchen was equipped with an outdoor chimney, but was still 8-14% higher than those household using cleaning energies, like electricity and gas. With a ventilator in the kitchen, the exposure among the population using clean energies could be further reduced by 10-24%. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. St. Vicent Ferrer’s Catalán sermon on St. Martin of Tours

    Directory of Open Access Journals (Sweden)

    Ferreiro, Alberto

    2013-12-01

    Full Text Available One of the most widely venerated saints in the Middle Ages was St. Martin of Tours whose cult continues to this day in many parts of the world. In the Middle Ages, he became as popular as other major saints such as Thomas Becket, Santiago de Compostela and the Virgin Mary. St. Martin’s cult became very prominent in the Iberian Peninsula before and after the emergence of the cult of Santiago de Compostela. In St. Vicent Ferrer’s voluminous sermons this one in Catalán is dedicated to this most venerated Gallic saint. The most important late antique and early medieval sources that form the background of this sermon are by Sulpicius Severus- the Gallus and Vita Sancti Martini. In the high Middle Ages, however, his cult was popularized through the Legenda Aurea written by the Dominican Jacobus of Voragine, who synthesized Sulpicius’ two works on St. Martin. Moreover, St. Vicent preached not to make any major doctrinal breakthroughs- his main interest was to evangelize, not to write academic theology- he nevertheless exhibited great creativity. The object of this study is St. Vicent’s Catalán sermon Alius Sermo Sancti Martini, CXXXIV.Uno de los santos más venerados en la edad media fue San Martín de Tours, cuyo culto continúa hasta hoy en muchas partes del mundo. En la edad media, se hizo tan popular como otros grandes Santos: Thomas Becket, Santiago de Compostela y la Virgen María. El culto de San Martín se hizo prominente en la Península Ibérica antes y después de la aparición del culto a Santiago de Compostela. En los sermones voluminosos de San Vicente Ferrer esta uno en Catalán que está dedicado a este santo tan venerado de Galia. Las fuentes más importantes procedentes de la antigu.edad tardía y principios medievales que forma el fondo de este sermón son Gallus y la Vita Sancti Martini de Sulpicio Severo. Sin embargo, en la alta edad media, su culto se popularizó a través de la Legenda Aurea escrita por el dominico

  5. Dance floor mechanical properties and dancer injuries in a touring professional ballet company.

    Science.gov (United States)

    Hopper, Luke S; Allen, Nick; Wyon, Matthew; Alderson, Jacqueline A; Elliott, Bruce C; Ackland, Timothy R

    2014-01-01

    The mechanical properties of the floors used by dancers have often been suggested to be associated with injury, yet limited etiological evidence is available to support this hypothesis. The dance floors at three theatres regularly used by a touring professional ballet company were mechanically quantified with the aim of comparing floor properties with injury incidence in dancers. Cross sectional. Test points on the floors were quantified in accordance with European Sports Surface Standard protocols for force reduction. Injuries and associated variables occurring within the ballet company dancers during activity on the three floors were recorded by the company's medical staff. An injury was recorded if a dancer experienced an incident that restricted the dancer from performing all normal training or performance activities for a 24 h period. Injuries were delimited to those occurring in the lower limbs or lumbar region during non-lifting tasks. Floor construction varied between venues and a range of floor mechanical properties were observed. None of the floors complied with the range of force reduction values required by the European Sport Surface Standards. The highest injury rate was observed on the floor with the greatest variability of force reduction magnitudes. No difference in injury frequency was observed between the venues with the highest and lowest mean force reduction magnitudes. Professional dancers can be required to perform on floors that may be inadequate for safe dance practice. Intra-floor force reduction variability may have a stronger association with injury risk than mean floor force reduction magnitude. Copyright © 2013 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  6. "A/S PET Baltija" kvalitātes pārvaldību sistēmu loma uzņēmuma konkurētspējas nodrošināšanā

    OpenAIRE

    Goldšteins, Jānis

    2012-01-01

    Bakalaura darba tēma ir ,,A/S PET Baltija’’ kvalitātes pārvaldību sistēmu loma uzņēmuma konkurētspējas nodrošināšanā. Bakalaura darba mērķis ir izpētīt A/S PET Baltija kvalitātes pārvaldības sistēmu darbības ietekmi uz uzņēmuma konkurētspēju, atklāt problēmas un izstrādāt priekšlikumus problēmu samazināšanai. Bakalaura darbs satur: 65 lapas, 4 tabulas, 24 attēlus. Darba pirmajā daļā autors analizē Eiropas Direktīvu un LR likumdošanas normatīvo aktu analīzi atkritumu apsaimniek...

  7. Latvijas kā medicīnas tūrisma galamērķa konkurētspēju ietekmējošie faktori

    OpenAIRE

    Sidorenko, Anna

    2012-01-01

    Bakalaura darba temats ir «Latvijas kā medicīnas tūrisma galamērķa konkurētspēju ietekmējošie faktori». Ņemot vērā starptautisko pieredzi, medicīnas pakalpojumu sniegšana ārvalstniekiem var nodrošināt papildus ienākumu avotu nacionālajai ekonomikai. Bakalaura darba mērķis ir identificēt un izpētīt faktorus, kas ietekmē Latvijas kā medicīnas tūrisma galamērķa konkurētspēju un izstrādāt priekšlikumus medicīnas pakalpojumu sniedzējiem un valsts pārvaldes institūcijām ar nolūku veicināt Latvij...

  8. STRATEGI PUBLIC RELATIONS MELALUI KEGIATAN PRESS TOUR PADA PROGRAM KERJA WISATA BAHARI DALAM MEMBANGUN CITRA PT. PELNI (PERSERO

    Directory of Open Access Journals (Sweden)

    Astri Dwi Ramadhani

    2015-11-01

    Full Text Available The problem in this research is negative report related PT. PELNI (Persero about the loss of the company. The existence of Low Cost Carrier (LCC which makes the image of PT. PELNI (Persero faded as many passengers aboard ships to aircraft. Subjects in this study consist of internal and external parties. From internal parties, namely Corporate Secretary, Public Relations, and Marketing Manager of PT. PELNI (Persero. While from external parties namely Journalist and User Services. The research method used is case study method with qualitative approach. Researchers use this method because of research questions pertaining to "how" and or "why" and contain the spirit of description in each explanation. Data collection techniques were conducted with in-depth interviews by resource persons. The result of the research shows that the use of public relations strategy through press tour activities conducted by Corporate Secretary of PT. PELNI (Persero is considered effective to get positive publicity. Publicity gained from the press tour activities have a positive impact for PT. PELNI (Persero. In addition to the positive image in the community also has a positive impact in the eyes of regulators.   Permasalahan dalam penelitian ini adalah pemberitaan negatif terkait PT. PELNI (Persero tentang kerugian perusahaan. Adanya Low Cost Carrier (LCC yang membuat citra PT. PELNI (Persero memudar karena banyak penumpang kapal yang beralih ke pesawat terbang. Subjek dalam penelitian ini terdiri dari pihak internal dan eksternal. Dari pihak internal, yaitu Corporate Secretary, Humas, dan Manager Pemasaran PT. PELNI (Persero. Sedangkan dari pihak eksternal yaitu Wartawan dan Pengguna Jasa. Metode penelitian yang digunakan adalah metode studi kasus dengan pendekatan kualitatif. Peneliti menggunakan metode ini karena pertanyaan penelitian berkenaan dengan “bagaimana” dan atau “mengapa” dan mengandung semangat deskripsi dalam setiap penjelasannya. Teknik

  9. Household air pollution and personal inhalation exposure to particles (TSP/PM2.5/PM1.0/PM0.25) in rural Shanxi, North China

    International Nuclear Information System (INIS)

    Huang, Ye; Du, Wei; Chen, Yuanchen; Shen, Guofeng; Su, Shu; Lin, Nan; Shen, Huizhong; Zhu, Dan; Yuan, Chenyi; Duan, Yonghong; Liu, Junfeng; Li, Bengang; Tao, Shu

    2017-01-01

    Personal exposure to size-segregated particles among rural residents in Shanxi, China in summer, 2011 were investigated using portable carried samplers (N = 84). Household air pollution was simultaneously studied using stationary samplers in nine homes. Information on household fuel types, cooking activity, smoking behavior, kitchen ventilation conditions etc., were also collected and discussed. The study found that even in the summer period, the daily average concentrations of PM 2.5 and PM 1.0 in the kitchen were as high as 376 ± 573 and 288 ± 397 μg/m 3 (N = 6), that were nearly 3 times of 114 ± 81 and 97 ± 77 μg/m 3 in the bedroom (N = 8), and significantly higher than those of 64 ± 28 and 47 ± 21 μg/m 3 in the outdoor air (N = 6). The personal daily exposure to PM 2.5 and PM 1.0 were 98 ± 52 and 77 ± 47 μg/m 3 , respectively, that were lower than the concentrations in the kitchen but higher than the outdoor levels. The mass fractions of PM 2.5 in TSP were 90%, 72%, 65% and 68% on average in the kitchen, bedroom, outdoor air and personal inhalation exposure, respectively, and moreover, a majority of particles in PM 2.5 had diameters less than 1.0 μm. Calculated time-weighted average exposure based on indoor and outdoor air concentrations and time spent indoor and outdoor were positively correlated but, was ∼33% lower than the directly measured exposure. The daily exposure among those burning traditional solid fuels could be lower by ∼41% if the kitchen was equipped with an outdoor chimney, but was still 8–14% higher than those household using cleaning energies, like electricity and gas. With a ventilator in the kitchen, the exposure among the population using clean energies could be further reduced by 10–24%. - Highlights: • High inhalation exposure of fine PM 2.5 and PM 1.0 among rural residents. • Smoking prevails on cooking in increasing exposure to finer particles. • PM exposure could be reduced by

  10. Advanced Harmony Search with Ant Colony Optimization for Solving the Traveling Salesman Problem

    Directory of Open Access Journals (Sweden)

    Ho-Yoeng Yun

    2013-01-01

    Full Text Available We propose a novel heuristic algorithm based on the methods of advanced Harmony Search and Ant Colony Optimization (AHS-ACO to effectively solve the Traveling Salesman Problem (TSP. The TSP, in general, is well known as an NP-complete problem, whose computational complexity increases exponentially by increasing the number of cities. In our algorithm, Ant Colony Optimization (ACO is used to search the local optimum in the solution space, followed by the use of the Harmony Search to escape the local optimum determined by the ACO and to move towards a global optimum. Experiments were performed to validate the efficiency of our algorithm through a comparison with other algorithms and the optimum solutions presented in the TSPLIB. The results indicate that our algorithm is capable of generating the optimum solution for most instances in the TSPLIB; moreover, our algorithm found better solutions in two cases (kroB100 and pr144 when compared with the optimum solution presented in the TSPLIB.

  11. An new self-organizing maps strategy for solving the traveling salesman problem

    International Nuclear Information System (INIS)

    Bai Yanping; Zhang Wendong; Jin Zhen

    2006-01-01

    This paper presents an approach to the well-known traveling salesman problem (TSP) using self-organizing maps (SOM). There are many types of SOM algorithms to solve the TSP found in the literature, whereas the purpose of this paper is to look for the incorporation of an efficient initialization methods and the definition of a parameters adaptation law to achieve better results and a faster convergence. Aspects of parameters adaptation, selecting the number of nodes of neurons, index of winner neurons and effect of the initial ordering of the cities, as well as the initial synaptic weights of the modified SOM algorithm are discussed. The complexity of the modified SOM algorithm is analyzed. The simulated results show an average deviation of 2.32% from the optimal tour length for a set of 12 TSP instances

  12. Improved Genetic and Simulating Annealing Algorithms to Solve the Traveling Salesman Problem Using Constraint Programming

    Directory of Open Access Journals (Sweden)

    M. Abdul-Niby

    2016-04-01

    Full Text Available The Traveling Salesman Problem (TSP is an integer programming problem that falls into the category of NP-Hard problems. As the problem become larger, there is no guarantee that optimal tours will be found within reasonable computation time. Heuristics techniques, like genetic algorithm and simulating annealing, can solve TSP instances with different levels of accuracy. Choosing which algorithm to use in order to get a best solution is still considered as a hard choice. This paper suggests domain reduction as a tool to be combined with any meta-heuristic so that the obtained results will be almost the same. The hybrid approach of combining domain reduction with any meta-heuristic encountered the challenge of choosing an algorithm that matches the TSP instance in order to get the best results.

  13. An new self-organizing maps strategy for solving the traveling salesman problem

    Energy Technology Data Exchange (ETDEWEB)

    Bai Yanping [Key Lab of Instrument Science and Dynamic Measurement of Ministry of Education, North University of China, No. 3, Xueyuan Road, TaiYuan, ShanXi 030051 (China)]. E-mail: baiyp@nuc.edu.cn; Zhang Wendong [Key Lab of Instrument Science and Dynamic Measurement of Ministry of Education, North University of China, No. 3, Xueyuan Road, TaiYuan, ShanXi 030051 (China)]. E-mail: wdzhang@nuc.edu.cn; Jin Zhen [Department of Applied Mathematics, North University of China, No. 3 Xueyuan Road, TaiYuan, ShanXi 030051 (China)

    2006-05-15

    This paper presents an approach to the well-known traveling salesman problem (TSP) using self-organizing maps (SOM). There are many types of SOM algorithms to solve the TSP found in the literature, whereas the purpose of this paper is to look for the incorporation of an efficient initialization methods and the definition of a parameters adaptation law to achieve better results and a faster convergence. Aspects of parameters adaptation, selecting the number of nodes of neurons, index of winner neurons and effect of the initial ordering of the cities, as well as the initial synaptic weights of the modified SOM algorithm are discussed. The complexity of the modified SOM algorithm is analyzed. The simulated results show an average deviation of 2.32% from the optimal tour length for a set of 12 TSP instances.

  14. Environmental hazard and risk characterisation of petroleum substances: a guided "walking tour" of petroleum hydrocarbons.

    Science.gov (United States)

    Bierkens, Johan; Geerts, Lieve

    2014-05-01

    Petroleum substances are used in large quantities, primarily as fuels. They are complex mixtures whose major constituents are hydrocarbons derived from crude oil by distillation and fractionation. Determining the complete molecular composition of petroleum and its refined products is not feasible with current analytical techniques because of the huge number of molecular components. This complex nature of petroleum products, with their varied number of constituents, all of them exhibiting different fate and effect characteristics, merits a dedicated hazard and risk assessment approach. From a regulatory perspective they pose a great challenge in a number of REACH processes, in particular in the context of dossier and substance evaluation but also for priority setting activities. In order to facilitate the performance of hazard and risk assessment for petroleum substances the European oil company association, CONCAWE, has developed the PETROTOX and PETRORISK spreadsheet models. Since the exact composition of many petroleum products is not known, an underlying assumption of the PETROTOX and PETRORISK tools is that the behaviour and fate of a total petroleum substance can be simulated based on the physical-chemical properties of representative structures mapped to hydrocarbon blocks (HBs) and on the relative share of each HB in the total mass of the product. To assess how differing chemical compositions affect the simulated chemical fate and toxicity of hydrocarbon mixtures, a series of model simulations were run using an artificial petroleum substance, containing 386 (PETROTOX) or 160 (PETRORISK) HBs belonging to different chemical classes and molecular weight ranges, but with equal mass assigned to each of them. To this artificial petroleum substance a guided series of subsequent modifications in mass allocation to a delineated number of HBs belonging to different chemical classes and carbon ranges was performed, in what we perceived as a guided "walking tour

  15. Variability of photosynthetic parameters of Pinus sibirica Du Tour needles under changing climatic factors

    Directory of Open Access Journals (Sweden)

    A.P. Zotikova

    2013-12-01

    Full Text Available The air temperature and relative humidity and the intensity of photosynthetically active radiation are the basic ecological factors determining geographical distribution of a species. Wood plant adaptation depends on the intensity of physiological and biochemicalprocesses of plants as a response to changing environmental factors. Investigations to reveal (detect the variability of modification andgenetic components of the photosynthetic parameters in needles of the Siberian cedar (Pinus sibirica Du Tour mountain ecotypes, distributed in central part of the Altai Mountains, were carried out. Also, the survey was extended to some experiments with these ecotypes introduced to mild climate and flat regions from south-western of Siberia. The length and thickness of needles, the size of chloroplasts, content of the photosynthetic pigments, and the functional activity of chloroplastsat the level of photo system II were the evaluated traits. Growing under mountainous conditions (at about 2000m elevation, the two-year-old needles were shorter and thicker and contained very large in size chloroplasts while the content of chlorophylls and carotinoids was twice lower than that in the local ecotype growing in the lowlands. On the other hand, more green and yellow pigments were found in needles of mountain ecotypes planted in the lowlands compared to the local lowland ectype trees. A decrease in pool of the photosynthetic pigments in the highlands ecotypes is probably due to decreased biosynthesis andincreased photo-destruction caused by severe light and temperature conditions. These parameters are likely to be associated withmodifications due to intense insolation, low temperature, ozone concentration, UV radiation, and other negative factors that are morepronounced at high elevation. Despite the large pool of accumulated photosynthetic pigments, the functional activity of chloroplasts in themountain ecotype at the level

  16. Specificities of Sightseeing Foot Tour Arrangement for History Related Street with Regard to Karl Marx Street in the Town of Irkutsk

    Science.gov (United States)

    Kulakov, A. I.; Shishkanov, V. S.

    2017-11-01

    The paper is devoted to the preparation of an innovative foot itinerary for tourists in Karl Marx Street in the town of Irkutsk. Methodology on preparation of sightseeing tours has been analysed by the authors. The analysis of the methodology has facilitated selecting the criteria to classify the excursions as well as the criteria for assessing and shortlisting the objects for excursion exposure. Some chosen criteria being used in tour arrangement and certain specificities of tour preparation have been revealed which are characteristic particularly for Karl Marx Street as a history-related one. It is also proved in the paper that the itinerary prepared for tourists is in full correspondence with the key innovation objectives in tourism.

  17. HEALTH INFO Information from the CHIS Board and Personnel Division: ABOUT BILLS FROM HOPITAL DE LA TOUR

    CERN Multimedia

    Personnel Division + CHISB

    1999-01-01

    The tariff agreement signed by CERN (and other international organisations) with Hospital de La Tour specifies that all bills paid within 30 days of the date of the invoice will enjoy a discount, to be deducted by the payer. The bills are labelled with a message to this effect.Physicians' fees, personal expenses as well as services from outside providers (e.g. ambulance companies or external laboratories) are however not part of the discount agreement. Bills for hospitalisation (i.e. with a stay in hospital longer than 28h) are normally directly paid by AUSTRIA, acting as a third-party payer.In May this year, Hospital de La Tour introduced a new (Y2K compliant) accounting and invoicing system. This implementation did not go as smoothly as planned and delayed the issuing of bills by two months. During the summer period, a special team of temporary staff was put in place to catch up on the delay. As a result of this, some bills were produced that contained errors and the sticky label mentioning the discount agr...

  18. Review of The Joy of x: A Guided Tour of Math, from One to Infinity by Steven Strogatz

    Directory of Open Access Journals (Sweden)

    Michael T. Catalano

    2014-07-01

    Full Text Available Strogatz, Steven. The Joy of x: A Guided Tour of Math, from One to Infinity, (New York, NY, Houghton Mifflin Harcourt, 2012. 316 pp. ISBN 978-0-547-51765-0 The Joy of x: A Guided Tour of Math, from One to Infinity, by Steven Strogatz, is an engaging and example-filled argument for mathematics as a valuable and enjoyable activity. The thirty chapters are divided into six parts, entitled Numbers, Relationships, Shapes, Change, Data, and Frontiers. The discussion ranges from intuitive explanations of basic concepts such as place value, the four arithmetic operations, percentage increase and decrease, and solving equations, to “higher” levels of mathematics such as calculus, probability and statistics, group theory, and the nature of infinity. As in John Allen Paulos’ work, Beyond Numeracy, the chapters are short and punchy, and they can be read independently. While the book is not specifically devoted to numeracy, several chapters, especially those in Part Five on Data, address ideas and examples relevant to quantitative literacy.

  19. A Cold Start Context-Aware Recommender System for Tour Planning Using Artificial Neural Network and Case Based Reasoning

    Directory of Open Access Journals (Sweden)

    Zahra Bahramian

    2017-01-01

    Full Text Available Nowadays, large amounts of tourism information and services are available over the Web. This makes it difficult for the user to search for some specific information such as selecting a tour in a given city as an ordered set of points of interest. Moreover, the user rarely knows all his needs upfront and his preferences may change during a recommendation process. The user may also have a limited number of initial ratings and most often the recommender system is likely to face the well-known cold start problem. The objective of the research presented in this paper is to introduce a hybrid interactive context-aware tourism recommender system that takes into account user’s feedbacks and additional contextual information. It offers personalized tours to the user based on his preferences thanks to the combination of a case based reasoning framework and an artificial neural network. The proposed method has been tried in the city of Tehran in Iran. The results show that the proposed method outperforms current artificial neural network methods and combinations of case based reasoning with k-nearest neighbor methods in terms of user effort, accuracy, and user satisfaction.

  20. Mesurer la ville par l’évaluation et la caractérisation du sol urbain : l’exemple de Tours To measure the city by the evaluation and characterization of urban land: the example of Tours

    Directory of Open Access Journals (Sweden)

    Amélie Laurent

    2011-01-01

    Full Text Available Deux thèses récentes d’archéologie ont été engagées sur la compréhension du sol urbain de Tours et menées dans le cadre des recherches archéologiques développées depuis une quarantaine d’années. Elles ont porté plus particulièrement sur l’analyse des caractéristiques et des principes d’exhaussement du sol urbain, correspondant à l’ensemble du dépôt archéologique de la ville.Ces travaux ont concerné deux échelles complémentaires traditionnellement employées en archéologie urbaine : l’évaluation, à l’échelle de la ville, et la caractérisation, à l’échelle du site. Fondées sur l’utilisation d’outils issus des Sciences de la Terre et appliqués dans une problématique d’histoire de la ville, deux nouvelles approches de la stratification des villes pré-industrielles ont été développées, la première concernant la microarchéologie, la seconde, la géotechnique appliquée au dépôt archéologique.Menées conjointement, les deux études présentent un double intérêt : le premier, d’ordre général, concerne la mise en œuvre d’une méthodologie applicable à tout phénomène urbain, en particulier par la création d’un référentiel commun des strates archéologiques, permettant de caractériser des dépôts indéterminés ; le second intérêt, plus ponctuel, concerne l’application de ces principes généraux à un cas particulier de formation du sol urbain, celui de Tours. La modélisation des résultats à l’échelle de la ville implique que l’acquisition des données sur le terrain intègre une problématique historique et topographique.Two recent archaeological theses have been involved with the understanding of the urban archaeology of Tours and conducted as part of the archaeological research developed over a 40-year period. They particularly cover the analysis of the characteristics and principles of the raising of urban land, corresponding to the entire archaeological