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Sample records for optimal state-feedback regulation

  1. Adaptive optimal stochastic state feedback control of resistive wall modes in tokamaks

    International Nuclear Information System (INIS)

    Sun, Z.; Sen, A.K.; Longman, R.W.

    2006-01-01

    An adaptive optimal stochastic state feedback control is developed to stabilize the resistive wall mode (RWM) instability in tokamaks. The extended least-square method with exponential forgetting factor and covariance resetting is used to identify (experimentally determine) the time-varying stochastic system model. A Kalman filter is used to estimate the system states. The estimated system states are passed on to an optimal state feedback controller to construct control inputs. The Kalman filter and the optimal state feedback controller are periodically redesigned online based on the identified system model. This adaptive controller can stabilize the time-dependent RWM in a slowly evolving tokamak discharge. This is accomplished within a time delay of roughly four times the inverse of the growth rate for the time-invariant model used

  2. A global bioheat model with self-tuning optimal regulation of body temperature using Hebbian feedback covariance learning.

    Science.gov (United States)

    Ong, M L; Ng, E Y K

    2005-12-01

    In the lower brain, body temperature is continually being regulated almost flawlessly despite huge fluctuations in ambient and physiological conditions that constantly threaten the well-being of the body. The underlying control problem defining thermal homeostasis is one of great enormity: Many systems and sub-systems are involved in temperature regulation and physiological processes are intrinsically complex and intertwined. Thus the defining control system has to take into account the complications of nonlinearities, system uncertainties, delayed feedback loops as well as internal and external disturbances. In this paper, we propose a self-tuning adaptive thermal controller based upon Hebbian feedback covariance learning where the system is to be regulated continually to best suit its environment. This hypothesis is supported in part by postulations of the presence of adaptive optimization behavior in biological systems of certain organisms which face limited resources vital for survival. We demonstrate the use of Hebbian feedback covariance learning as a possible self-adaptive controller in body temperature regulation. The model postulates an important role of Hebbian covariance adaptation as a means of reinforcement learning in the thermal controller. The passive system is based on a simplified 2-node core and shell representation of the body, where global responses are captured. Model predictions are consistent with observed thermoregulatory responses to conditions of exercise and rest, and heat and cold stress. An important implication of the model is that optimal physiological behaviors arising from self-tuning adaptive regulation in the thermal controller may be responsible for the departure from homeostasis in abnormal states, e.g., fever. This was previously unexplained using the conventional "set-point" control theory.

  3. Application of non-linear discretetime feedback regulators with assignable closed-loop dynamics

    Directory of Open Access Journals (Sweden)

    Dubljević Stevan

    2003-01-01

    Full Text Available In the present work the application of a new approach is demonstrated to a discrete-time state feedback regulator synthesis with feedback linearization and pole-placement for non-linear discrete-time systems. Under the simultaneous implementation of a non-linear coordinate transformation and a non-linear state feedback law computed through the solution of a system of non-linear functional equations, both the feedback linearization and pole-placement design objectives were accomplished. The non-linear state feedback regulator synthesis method was applied to a continuous stirred tank reactor (CSTR under non-isothermal operating conditions that exhibits steady-state multiplicity. The control objective was to regulate the reactor at the middle unstable steady state by manipulating the rate of input heat in the reactor. Simulation studies were performed to evaluate the performance of the proposed non-linear state feedback regulator, as it was shown a non-linear state feedback regulator clearly outperformed a standard linear one, especially in the presence of adverse disturbance under which linear regulation at the unstable steady state was not feasible.

  4. Correlations in state space can cause sub-optimal adaptation of optimal feedback control models.

    Science.gov (United States)

    Aprasoff, Jonathan; Donchin, Opher

    2012-04-01

    Control of our movements is apparently facilitated by an adaptive internal model in the cerebellum. It was long thought that this internal model implemented an adaptive inverse model and generated motor commands, but recently many reject that idea in favor of a forward model hypothesis. In theory, the forward model predicts upcoming state during reaching movements so the motor cortex can generate appropriate motor commands. Recent computational models of this process rely on the optimal feedback control (OFC) framework of control theory. OFC is a powerful tool for describing motor control, it does not describe adaptation. Some assume that adaptation of the forward model alone could explain motor adaptation, but this is widely understood to be overly simplistic. However, an adaptive optimal controller is difficult to implement. A reasonable alternative is to allow forward model adaptation to 're-tune' the controller. Our simulations show that, as expected, forward model adaptation alone does not produce optimal trajectories during reaching movements perturbed by force fields. However, they also show that re-optimizing the controller from the forward model can be sub-optimal. This is because, in a system with state correlations or redundancies, accurate prediction requires different information than optimal control. We find that adding noise to the movements that matches noise found in human data is enough to overcome this problem. However, since the state space for control of real movements is far more complex than in our simple simulations, the effects of correlations on re-adaptation of the controller from the forward model cannot be overlooked.

  5. When Optimal Feedback Control Is Not Enough: Feedforward Strategies Are Required for Optimal Control with Active Sensing.

    Directory of Open Access Journals (Sweden)

    Sang-Hoon Yeo

    2016-12-01

    Full Text Available Movement planning is thought to be primarily determined by motor costs such as inaccuracy and effort. Solving for the optimal plan that minimizes these costs typically leads to specifying a time-varying feedback controller which both generates the movement and can optimally correct for errors that arise within a movement. However, the quality of the sensory feedback during a movement can depend substantially on the generated movement. We show that by incorporating such state-dependent sensory feedback, the optimal solution incorporates active sensing and is no longer a pure feedback process but includes a significant feedforward component. To examine whether people take into account such state-dependency in sensory feedback we asked people to make movements in which we controlled the reliability of sensory feedback. We made the visibility of the hand state-dependent, such that the visibility was proportional to the component of hand velocity in a particular direction. Subjects gradually adapted to such a sensory perturbation by making curved hand movements. In particular, they appeared to control the late visibility of the movement matching predictions of the optimal controller with state-dependent sensory noise. Our results show that trajectory planning is not only sensitive to motor costs but takes sensory costs into account and argues for optimal control of movement in which feedforward commands can play a significant role.

  6. When Optimal Feedback Control Is Not Enough: Feedforward Strategies Are Required for Optimal Control with Active Sensing.

    Science.gov (United States)

    Yeo, Sang-Hoon; Franklin, David W; Wolpert, Daniel M

    2016-12-01

    Movement planning is thought to be primarily determined by motor costs such as inaccuracy and effort. Solving for the optimal plan that minimizes these costs typically leads to specifying a time-varying feedback controller which both generates the movement and can optimally correct for errors that arise within a movement. However, the quality of the sensory feedback during a movement can depend substantially on the generated movement. We show that by incorporating such state-dependent sensory feedback, the optimal solution incorporates active sensing and is no longer a pure feedback process but includes a significant feedforward component. To examine whether people take into account such state-dependency in sensory feedback we asked people to make movements in which we controlled the reliability of sensory feedback. We made the visibility of the hand state-dependent, such that the visibility was proportional to the component of hand velocity in a particular direction. Subjects gradually adapted to such a sensory perturbation by making curved hand movements. In particular, they appeared to control the late visibility of the movement matching predictions of the optimal controller with state-dependent sensory noise. Our results show that trajectory planning is not only sensitive to motor costs but takes sensory costs into account and argues for optimal control of movement in which feedforward commands can play a significant role.

  7. Voltage and Current Regulators Design of Power Converters in Islanded Microgrids based on State Feedback Decoupling

    DEFF Research Database (Denmark)

    Federico, de Bosio; de Sousa Ribeiro, Luiz Antonio; Freijedo Fernandez, Francisco Daniel

    2016-01-01

    In stand-alone microgrids based on voltage source inverters state feedback coupling between the capacitor voltage and inductor current degrades significantly the dynamics performance of voltage and current regulators. The decoupling of the controlled states is proposed, considering the limitations...

  8. Optimal control of nonlinear continuous-time systems in strict-feedback form.

    Science.gov (United States)

    Zargarzadeh, Hassan; Dierks, Travis; Jagannathan, Sarangapani

    2015-10-01

    This paper proposes a novel optimal tracking control scheme for nonlinear continuous-time systems in strict-feedback form with uncertain dynamics. The optimal tracking problem is transformed into an equivalent optimal regulation problem through a feedforward adaptive control input that is generated by modifying the standard backstepping technique. Subsequently, a neural network-based optimal control scheme is introduced to estimate the cost, or value function, over an infinite horizon for the resulting nonlinear continuous-time systems in affine form when the internal dynamics are unknown. The estimated cost function is then used to obtain the optimal feedback control input; therefore, the overall optimal control input for the nonlinear continuous-time system in strict-feedback form includes the feedforward plus the optimal feedback terms. It is shown that the estimated cost function minimizes the Hamilton-Jacobi-Bellman estimation error in a forward-in-time manner without using any value or policy iterations. Finally, optimal output feedback control is introduced through the design of a suitable observer. Lyapunov theory is utilized to show the overall stability of the proposed schemes without requiring an initial admissible controller. Simulation examples are provided to validate the theoretical results.

  9. Investigation, development and application of optimal output feedback theory. Volume 2: Development of an optimal, limited state feedback outer-loop digital flight control system for 3-D terminal area operation

    Science.gov (United States)

    Broussard, J. R.; Halyo, N.

    1984-01-01

    This report contains the development of a digital outer-loop three dimensional radio navigation (3-D RNAV) flight control system for a small commercial jet transport. The outer-loop control system is designed using optimal stochastic limited state feedback techniques. Options investigated using the optimal limited state feedback approach include integrated versus hierarchical control loop designs, 20 samples per second versus 5 samples per second outer-loop operation and alternative Type 1 integration command errors. Command generator tracking techniques used in the digital control design enable the jet transport to automatically track arbitrary curved flight paths generated by waypoints. The performance of the design is demonstrated using detailed nonlinear aircraft simulations in the terminal area, frequency domain multi-input sigma plots, frequency domain single-input Bode plots and closed-loop poles. The response of the system to a severe wind shear during a landing approach is also presented.

  10. Robust state feedback controller design of STATCOM using chaotic optimization algorithm

    Directory of Open Access Journals (Sweden)

    Safari Amin

    2010-01-01

    Full Text Available In this paper, a new design technique for the design of robust state feedback controller for static synchronous compensator (STATCOM using Chaotic Optimization Algorithm (COA is presented. The design is formulated as an optimization problem which is solved by the COA. Since chaotic planning enjoys reliability, ergodicity and stochastic feature, the proposed technique presents chaos mapping using Lozi map chaotic sequences which increases its convergence rate. To ensure the robustness of the proposed damping controller, the design process takes into account a wide range of operating conditions and system configurations. The simulation results reveal that the proposed controller has an excellent capability in damping power system low frequency oscillations and enhances greatly the dynamic stability of the power systems. Moreover, the system performance analysis under different operating conditions shows that the phase based controller is superior compare to the magnitude based controller.

  11. A Feedback Optimal Control Algorithm with Optimal Measurement Time Points

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    Felix Jost

    2017-02-01

    Full Text Available Nonlinear model predictive control has been established as a powerful methodology to provide feedback for dynamic processes over the last decades. In practice it is usually combined with parameter and state estimation techniques, which allows to cope with uncertainty on many levels. To reduce the uncertainty it has also been suggested to include optimal experimental design into the sequential process of estimation and control calculation. Most of the focus so far was on dual control approaches, i.e., on using the controls to simultaneously excite the system dynamics (learning as well as minimizing a given objective (performing. We propose a new algorithm, which sequentially solves robust optimal control, optimal experimental design, state and parameter estimation problems. Thus, we decouple the control and the experimental design problems. This has the advantages that we can analyze the impact of measurement timing (sampling independently, and is practically relevant for applications with either an ethical limitation on system excitation (e.g., chemotherapy treatment or the need for fast feedback. The algorithm shows promising results with a 36% reduction of parameter uncertainties for the Lotka-Volterra fishing benchmark example.

  12. Full State Feedback Control for Virtual Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, Jay Tillay [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-09-01

    This report presents an object-oriented implementation of full state feedback control for virtual power plants (VPP). The components of the VPP full state feedback control are (1) objectoriented high-fidelity modeling for all devices in the VPP; (2) Distribution System Distributed Quasi-Dynamic State Estimation (DS-DQSE) that enables full observability of the VPP by augmenting actual measurements with virtual, derived and pseudo measurements and performing the Quasi-Dynamic State Estimation (QSE) in a distributed manner, and (3) automated formulation of the Optimal Power Flow (OPF) in real time using the output of the DS-DQSE, and solving the distributed OPF to provide the optimal control commands to the DERs of the VPP.

  13. Optimal Power Flow Using Gbest-Guided Cuckoo Search Algorithm with Feedback Control Strategy and Constraint Domination Rule

    Directory of Open Access Journals (Sweden)

    Gonggui Chen

    2017-01-01

    Full Text Available The optimal power flow (OPF is well-known as a significant optimization tool for the security and economic operation of power system, and OPF problem is a complex nonlinear, nondifferentiable programming problem. Thus this paper proposes a Gbest-guided cuckoo search algorithm with the feedback control strategy and constraint domination rule which is named as FCGCS algorithm for solving OPF problem and getting optimal solution. This FCGCS algorithm is guided by the global best solution for strengthening exploitation ability. Feedback control strategy is devised to dynamically regulate the control parameters according to actual and specific feedback value in the simulation process. And the constraint domination rule can efficiently handle inequality constraints on state variables, which is superior to traditional penalty function method. The performance of FCGCS algorithm is tested and validated on the IEEE 30-bus and IEEE 57-bus example systems, and simulation results are compared with different methods obtained from other literatures recently. The comparison results indicate that FCGCS algorithm can provide high-quality feasible solutions for different OPF problems.

  14. Optimal feedback control of the forced van der Pol system

    International Nuclear Information System (INIS)

    Chagas, T.P.; Toledo, B.A.; Rempel, E.L.; Chian, A.C.-L.; Valdivia, J.A.

    2012-01-01

    A simple feedback control strategy for chaotic systems is investigated using the forced van der Pol system as an example. The strategy regards chaos control as an optimization problem, where the maximum magnitude Floquet multiplier of a target unstable periodic orbit (UPO) is used as a cost function that needs to be minimized. Thus, the method obtains the optimal control gain in terms of the stability of the target UPO. This strategy was recently proposed for the proportional feedback control (PFC) method. Here, it is extended to the highly popular delayed feedback control (DFC) method. Since the DFC method treats the system as a delay-differential equation whose phase space is infinite-dimensional, the characteristic multipliers are found through a truncation in the number of delayed states. Control of a target UPO is achieved for several values of the forcing amplitude. We compare the DFC and PFC methods in terms of stability of the controlled orbit, steady state error and control effort.

  15. New numerical methods for open-loop and feedback solutions to dynamic optimization problems

    Science.gov (United States)

    Ghosh, Pradipto

    is that the resulting control law has an algebraic closed-form structure. The proposed method uses an optimal spatial statistical predictor called universal kriging to construct the surrogate model of a feedback controller, which is capable of quickly predicting an optimal control estimate based on current state (and time) information. With universal kriging, an approximation to the optimal feedback map is computed by conceptualizing a set of state-control samples from pre-computed extremals to be a particular realization of a jointly Gaussian spatial process. Feedback policies are computed for a variety of example dynamic optimization problems in order to evaluate the effectiveness of this methodology. This feedback synthesis approach is found to combine good numerical accuracy with low computational overhead, making it a suitable candidate for real-time applications. Particle swarm and universal kriging are combined for a capstone example, a near optimal, near-admissible, full-state feedback control law is computed and tested for the heat-load-limited atmospheric-turn guidance of an aeroassisted transfer vehicle. The performance of this explicit guidance scheme is found to be very promising; initial errors in atmospheric entry due to simulated thruster misfirings are found to be accurately corrected while closely respecting the algebraic state-inequality constraint.

  16. Time-optimal feedback control for linear systems

    International Nuclear Information System (INIS)

    Mirica, S.

    1976-01-01

    The paper deals with the results of qualitative investigations of the time-optimal feedback control for linear systems with constant coefficients. In the first section, after some definitions and notations, two examples are given and it is shown that even the time-optimal control problem for linear systems with constant coefficients which looked like ''completely solved'' requires a further qualitative investigation of the stability to ''permanent perturbations'' of optimal feedback control. In the second section some basic results of the linear time-optimal control problem are reviewed. The third section deals with the definition of Boltyanskii's ''regular synthesis'' and its connection to Filippov's theory of right-hand side discontinuous differential equations. In the fourth section a theorem is proved concerning the stability to perturbations of time-optimal feedback control for linear systems with scalar control. In the last two sections it is proved that, if the matrix which defines the system has only real eigenvalues or is three-dimensional, the time-optimal feedback control defines a regular synthesis and therefore is stable to perturbations. (author)

  17. Design and Validation of Optimized Feedforward with Robust Feedback Control of a Nuclear Reactor

    International Nuclear Information System (INIS)

    Shaffer, Roman; He Weidong; Edwards, Robert M.

    2004-01-01

    Design applications for robust feedback and optimized feedforward control, with confirming results from experiments conducted on the Pennsylvania State University TRIGA reactor, are presented. The combination of feedforward and feedback control techniques complement each other in that robust control offers guaranteed closed-loop stability in the presence of uncertainties, and optimized feedforward offers an approach to achieving performance that is sometimes limited by overly conservative robust feedback control. The design approach taken in this work combines these techniques by first designing robust feedback control. Alternative methods for specifying a low-order linear model and uncertainty specifications, while seeking as much performance as possible, are discussed and evaluated. To achieve desired performance characteristics, the optimized feedforward control is then computed by using the nominal nonlinear plant model that incorporates the robust feedback control

  18. Feedback control of a Darrieus wind turbine and optimization of the produced energy

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    Maurin, T.; Henry, B.; Devos, F.; de Saint Louvent, B.; Gosselin, J.

    1984-03-01

    A microprocessor-driven control system, applied to the feedback control of a Darrieus wind turbine is presented. The use of a dc machine as a generator to recover the energy and as a motor to start the engine, allows simplified power electronics. The architecture of the control unit is built to ensure four different functions: starting, optimization of the recoverable energy, regulation of the speed, and braking. An experimental study of the system in a wind tunnel allowed optimization of the coefficients of the proportional and integral (pi) control algorithm. The electrical energy recovery was found to be much more efficient using the feedback system than without the control unit. This system allows a better characterization of the wind turbine and a regulation adapted to the wind statistics observed in one given geographical location.

  19. Model-based Optimization and Feedback Control of the Current Density Profile Evolution in NSTX-U

    Science.gov (United States)

    Ilhan, Zeki Okan

    Nuclear fusion research is a highly challenging, multidisciplinary field seeking contributions from both plasma physics and multiple engineering areas. As an application of plasma control engineering, this dissertation mainly explores methods to control the current density profile evolution within the National Spherical Torus eXperiment-Upgrade (NSTX-U), which is a substantial upgrade based on the NSTX device, which is located in Princeton Plasma Physics Laboratory (PPPL), Princeton, NJ. Active control of the toroidal current density profile is among those plasma control milestones that the NSTX-U program must achieve to realize its next-step operational goals, which are characterized by high-performance, long-pulse, MHD-stable plasma operation with neutral beam heating. Therefore, the aim of this work is to develop model-based, feedforward and feedback controllers that can enable time regulation of the current density profile in NSTX-U by actuating the total plasma current, electron density, and the powers of the individual neutral beam injectors. Motivated by the coupled, nonlinear, multivariable, distributed-parameter plasma dynamics, the first step towards control design is the development of a physics-based, control-oriented model for the current profile evolution in NSTX-U in response to non-inductive current drives and heating systems. Numerical simulations of the proposed control-oriented model show qualitative agreement with the high-fidelity physics code TRANSP. The next step is to utilize the proposed control-oriented model to design an open-loop actuator trajectory optimizer. Given a desired operating state, the optimizer produces the actuator trajectories that can steer the plasma to such state. The objective of the feedforward control design is to provide a more systematic approach to advanced scenario planning in NSTX-U since the development of such scenarios is conventionally carried out experimentally by modifying the tokamak's actuator

  20. A steady state analysis indicates that negative feedback regulation of PTP1B by Akt elicits bistability in insulin-stimulated GLUT4 translocation

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    Giri Lopamudra

    2004-08-01

    Full Text Available Abstract Background The phenomenon of switch-like response to graded input signal is the theme involved in various signaling pathways in living systems. Positive feedback loops or double negative feedback loops embedded with nonlinearity exhibit these switch-like bistable responses. Such feedback regulations exist in insulin signaling pathway as well. Methods In the current manuscript, a steady state analysis of the metabolic insulin-signaling pathway is presented. The threshold concentration of insulin required for glucose transporter GLUT4 translocation was studied with variation in system parameters and component concentrations. The dose response curves of GLUT4 translocation at various concentration of insulin obtained by steady state analysis were quantified in-terms of half saturation constant. Results We show that, insulin-stimulated GLUT4 translocation can operate as a bistable switch, which ensures that GLUT4 settles between two discrete, but mutually exclusive stable steady states. The threshold concentration of insulin required for GLUT4 translocation changes with variation in system parameters and component concentrations, thus providing insights into possible pathological conditions. Conclusion A steady state analysis indicates that negative feedback regulation of phosphatase PTP1B by Akt elicits bistability in insulin-stimulated GLUT4 translocation. The threshold concentration of insulin required for GLUT4 translocation and the corresponding bistable response at different system parameters and component concentrations was compared with reported experimental observations on specific defects in regulation of the system.

  1. Factorization and the synthesis of optimal feedback gains for distributed parameter systems

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    Milman, Mark H.; Scheid, Robert E.

    1990-01-01

    An approach based on Volterra factorization leads to a new methodology for the analysis and synthesis of the optimal feedback gain in the finite-time linear quadratic control problem for distributed parameter systems. The approach circumvents the need for solving and analyzing Riccati equations and provides a more transparent connection between the system dynamics and the optimal gain. The general results are further extended and specialized for the case where the underlying state is characterized by autonomous differential-delay dynamics. Numerical examples are given to illustrate the second-order convergence rate that is derived for an approximation scheme for the optimal feedback gain in the differential-delay problem.

  2. Computation of the target state and feedback controls for time optimal consensus in multi-agent systems

    Science.gov (United States)

    Mulla, Ameer K.; Patil, Deepak U.; Chakraborty, Debraj

    2018-02-01

    N identical agents with bounded inputs aim to reach a common target state (consensus) in the minimum possible time. Algorithms for computing this time-optimal consensus point, the control law to be used by each agent and the time taken for the consensus to occur, are proposed. Two types of multi-agent systems are considered, namely (1) coupled single-integrator agents on a plane and, (2) double-integrator agents on a line. At the initial time instant, each agent is assumed to have access to the state information of all the other agents. An algorithm, using convexity of attainable sets and Helly's theorem, is proposed, to compute the final consensus target state and the minimum time to achieve this consensus. Further, parts of the computation are parallelised amongst the agents such that each agent has to perform computations of O(N2) run time complexity. Finally, local feedback time-optimal control laws are synthesised to drive each agent to the target point in minimum time. During this part of the operation, the controller for each agent uses measurements of only its own states and does not need to communicate with any neighbouring agents.

  3. On-line computer control of a nuclear reactor using optimal control and state estimation methods

    International Nuclear Information System (INIS)

    Tye, C.

    1980-01-01

    This paper describes the experimental implementation of a nuclear reactor control system using combined optimal state feedback based on the Quadratic Regulator and state estimation using Kalman filtering techniques. The results obtained from the experiments indicate that a reactor control loop designed using this approach has improved stability margins, greater speed of response and noise filtering properties compared with a conventional reactor control loop. 11 refs

  4. Post-translational regulation enables robust p53 regulation.

    Science.gov (United States)

    Shin, Yong-Jun; Chen, Kai-Yuan; Sayed, Ali H; Hencey, Brandon; Shen, Xiling

    2013-08-30

    The tumor suppressor protein p53 plays important roles in DNA damage repair, cell cycle arrest and apoptosis. Due to its critical functions, the level of p53 is tightly regulated by a negative feedback mechanism to increase its tolerance towards fluctuations and disturbances. Interestingly, the p53 level is controlled by post-translational regulation rather than transcriptional regulation in this feedback mechanism. We analyzed the dynamics of this feedback to understand whether post-translational regulation provides any advantages over transcriptional regulation in regard to disturbance rejection. When a disturbance happens, even though negative feedback reduces the steady-state error, it can cause a system to become less stable and transiently overshoots, which may erroneously trigger downstream reactions. Therefore, the system needs to balance the trade-off between steady-state and transient errors. Feedback control and adaptive estimation theories revealed that post-translational regulation achieves a better trade-off than transcriptional regulation, contributing to a more steady level of p53 under the influence of noise and disturbances. Furthermore, post-translational regulation enables cells to respond more promptly to stress conditions with consistent amplitude. However, for better disturbance rejection, the p53- Mdm2 negative feedback has to pay a price of higher stochastic noise. Our analyses suggest that the p53-Mdm2 feedback favors regulatory mechanisms that provide the optimal trade-offs for dynamic control.

  5. Parameter identification technique for uncertain chaotic systems using state feedback and steady-state analysis.

    Science.gov (United States)

    Zaher, Ashraf A

    2008-03-01

    A technique is introduced for identifying uncertain and/or unknown parameters of chaotic dynamical systems via using simple state feedback. The proposed technique is based on bringing the system into a stable steady state and then solving for the unknown parameters using a simple algebraic method that requires access to the complete or partial states of the system depending on the dynamical model of the chaotic system. The choice of the state feedback is optimized in terms of practicality and causality via employing a single feedback signal and tuning the feedback gain to ensure both stability and identifiability. The case when only a single scalar time series of one of the states is available is also considered and it is demonstrated that a synchronization-based state observer can be augmented to the state feedback to address this problem. A detailed case study using the Lorenz system is used to exemplify the suggested technique. In addition, both the Rössler and Chua systems are examined as possible candidates for utilizing the proposed methodology when partial identification of the unknown parameters is considered. Finally, the dependence of the proposed technique on the structure of the chaotic dynamical model and the operating conditions is discussed and its advantages and limitations are highlighted via comparing it with other methods reported in the literature.

  6. Static inverter with synchronous output waveform synthesized by time-optimal-response feedback

    Science.gov (United States)

    Kernick, A.; Stechschulte, D. L.; Shireman, D. W.

    1976-01-01

    Time-optimal-response 'bang-bang' or 'bang-hang' technique, using four feedback control loops, synthesizes static-inverter sinusoidal output waveform by self-oscillatory but yet synchronous pulse-frequency-modulation (SPFM). A single modular power stage per phase of ac output entails the minimum of circuit complexity while providing by feedback synthesis individual phase voltage regulation, phase position control and inherent compensation simultaneously for line and load disturbances. Clipped sinewave performance is described under off-limit load or input voltage conditions. Also, approaches to high power levels, 3-phase arraying and parallel modular connection are given.

  7. The Regulation of Behavioral Plasticity by Performance-Based Feedback and an Experimental Test with Avian Egg Production.

    Science.gov (United States)

    Sockman, Keith W

    2016-05-01

    Optimizing plasticity in behavioral performances requires the abilities to regulate physiological effort and to estimate the effects of the environment. To describe how performance-based feedback could play a role in regulating recursive or continuous behavioral performances, I developed two models, one (environmental feedback) that assumes an initial ability to regulate effort but not to predict the effects of the environment and the other (effort feedback) that assumes an initial ability to predict the effects of the environment but not to regulate effort. I tested them by manipulating feedback on egg production, using an egg-substitution experiment in wild, free-ranging Lincoln's sparrows (Melospiza lincolnii). I discovered that females adjusted the size of their clutches' third laid eggs in response to the size of an experimentally substituted first laid egg, such that the size of the third laid egg increased with the size of the substitute. Results were largely consistent with the environmental feedback model, though small portions of the response surface were consistent with the effort feedback model or with neither. Regardless, such feedback-based regulation predicted by either model may help females maximize net benefits of egg production and may be a basis for mechanisms regulating a wide range of other behavioral performances, as well.

  8. State-feedback control of fuzzy discrete-event systems.

    Science.gov (United States)

    Lin, Feng; Ying, Hao

    2010-06-01

    In a 2002 paper, we combined fuzzy logic with discrete-event systems (DESs) and established an automaton model of fuzzy DESs (FDESs). The model can effectively represent deterministic uncertainties and vagueness, as well as human subjective observation and judgment inherent to many real-world problems, particularly those in biomedicine. We also investigated optimal control of FDESs and applied the results to optimize HIV/AIDS treatments for individual patients. Since then, other researchers have investigated supervisory control problems in FDESs, and several results have been obtained. These results are mostly derived by extending the traditional supervisory control of (crisp) DESs, which are string based. In this paper, we develop state-feedback control of FDESs that is different from the supervisory control extensions. We use state space to describe the system behaviors and use state feedback in control. Both disablement and enforcement are allowed. Furthermore, we study controllability based on the state space and prove that a controller exists if and only if the controlled system behavior is (state-based) controllable. We discuss various properties of the state-based controllability. Aside from novelty, the proposed new framework has the advantages of being able to address a wide range of practical problems that cannot be effectively dealt with by existing approaches. We use the diabetes treatment as an example to illustrate some key aspects of our theoretical results.

  9. Optimal allocation of reviewers for peer feedback

    DEFF Research Database (Denmark)

    Wind, David Kofoed; Jensen, Ulf Aslak; Jørgensen, Rasmus Malthe

    2017-01-01

    feedback to be effective students should give and receive useful feedback. A key challenge in peer feedback is allocating the feedback givers in a good way. It is important that reviewers are allocated to submissions such that the feedback distribution is fair - meaning that all students receive good......Peer feedback is the act of letting students give feedback to each other on submitted work. There are multiple reasons to use peer feedback, including students getting more feedback, time saving for teachers and increased learning by letting students reflect on work by others. In order for peer...... indicated the quality of the feedback. Using this model together with historical data we calculate the feedback-giving skill of each student and uses that as input to an allocation algorithm that assigns submissions to reviewers, in order to optimize the feedback quality for all students. We test...

  10. Short-Term State Forecasting-Based Optimal Voltage Regulation in Distribution Systems: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Rui; Jiang, Huaiguang; Zhang, Yingchen

    2017-05-17

    A novel short-term state forecasting-based optimal power flow (OPF) approach for distribution system voltage regulation is proposed in this paper. An extreme learning machine (ELM) based state forecaster is developed to accurately predict system states (voltage magnitudes and angles) in the near future. Based on the forecast system states, a dynamically weighted three-phase AC OPF problem is formulated to minimize the voltage violations with higher penalization on buses which are forecast to have higher voltage violations in the near future. By solving the proposed OPF problem, the controllable resources in the system are optimally coordinated to alleviate the potential severe voltage violations and improve the overall voltage profile. The proposed approach has been tested in a 12-bus distribution system and simulation results are presented to demonstrate the performance of the proposed approach.

  11. Feedback optimal control of dynamic stochastic two-machine flowshop with a finite buffer

    Directory of Open Access Journals (Sweden)

    Thang Diep

    2010-06-01

    Full Text Available This paper examines the optimization of production involving a tandem two-machine system producing a single part type, with each machine being subject to random breakdowns and repairs. An analytical model is formulated with a view to solving an optimal stochastic production problem of the system with machines having up-downtime non-exponential distributions. The model developed is obtained by using a dynamic programming approach and a semi-Markov process. The control problem aims to find the production rates needed by the machines to meet the demand rate, through a minimization of the inventory/shortage cost. Using the Bellman principle, the optimality conditions obtained satisfy the Hamilton-Jacobi-Bellman equation, which depends on time and system states, and ultimately, leads to a feedback control. Consequently, the new model enables us to improve the coefficient of variation (CVup/down to be less than one while it is equal to one in Markov model. Heuristics methods are used to involve the problem because of the difficulty of the analytical model using several states, and to show what control law should be used in each system state (i.e., including Kanban, feedback and CONWIP control. Numerical methods are used to solve the optimality conditions and to show how a machine should produce.

  12. A numerical algorithm for optimal feedback gains in high dimensional linear quadratic regulator problems

    Science.gov (United States)

    Banks, H. T.; Ito, K.

    1991-01-01

    A hybrid method for computing the feedback gains in linear quadratic regulator problem is proposed. The method, which combines use of a Chandrasekhar type system with an iteration of the Newton-Kleinman form with variable acceleration parameter Smith schemes, is formulated to efficiently compute directly the feedback gains rather than solutions of an associated Riccati equation. The hybrid method is particularly appropriate when used with large dimensional systems such as those arising in approximating infinite-dimensional (distributed parameter) control systems (e.g., those governed by delay-differential and partial differential equations). Computational advantages of the proposed algorithm over the standard eigenvector (Potter, Laub-Schur) based techniques are discussed, and numerical evidence of the efficacy of these ideas is presented.

  13. Aeroassisted orbital maneuvering using Lyapunov optimal feedback control

    Science.gov (United States)

    Grantham, Walter J.; Lee, Byoung-Soo

    1987-01-01

    A Liapunov optimal feedback controller incorporating a preferred direction of motion at each state of the system which is opposite to the gradient of a specified descent function is developed for aeroassisted orbital transfer from high-earth orbit to LEO. The performances of the Liapunov controller and a calculus-of-variations open-loop minimum-fuel controller, both of which are based on the 1962 U.S. Standard Atmosphere, are simulated using both the 1962 U.S. Standard Atmosphere and an atmosphere corresponding to the STS-6 Space Shuttle flight. In the STS-6 atmosphere, the calculus-of-variations open-loop controller fails to exit the atmosphere, while the Liapunov controller achieves the optimal minimum-fuel conditions, despite the + or - 40 percent fluctuations in the STS-6 atmosphere.

  14. Event-Triggered Distributed Approximate Optimal State and Output Control of Affine Nonlinear Interconnected Systems.

    Science.gov (United States)

    Narayanan, Vignesh; Jagannathan, Sarangapani

    2017-06-08

    This paper presents an approximate optimal distributed control scheme for a known interconnected system composed of input affine nonlinear subsystems using event-triggered state and output feedback via a novel hybrid learning scheme. First, the cost function for the overall system is redefined as the sum of cost functions of individual subsystems. A distributed optimal control policy for the interconnected system is developed using the optimal value function of each subsystem. To generate the optimal control policy, forward-in-time, neural networks are employed to reconstruct the unknown optimal value function at each subsystem online. In order to retain the advantages of event-triggered feedback for an adaptive optimal controller, a novel hybrid learning scheme is proposed to reduce the convergence time for the learning algorithm. The development is based on the observation that, in the event-triggered feedback, the sampling instants are dynamic and results in variable interevent time. To relax the requirement of entire state measurements, an extended nonlinear observer is designed at each subsystem to recover the system internal states from the measurable feedback. Using a Lyapunov-based analysis, it is demonstrated that the system states and the observer errors remain locally uniformly ultimately bounded and the control policy converges to a neighborhood of the optimal policy. Simulation results are presented to demonstrate the performance of the developed controller.

  15. Learning-Based Adaptive Optimal Tracking Control of Strict-Feedback Nonlinear Systems.

    Science.gov (United States)

    Gao, Weinan; Jiang, Zhong-Ping; Weinan Gao; Zhong-Ping Jiang; Gao, Weinan; Jiang, Zhong-Ping

    2018-06-01

    This paper proposes a novel data-driven control approach to address the problem of adaptive optimal tracking for a class of nonlinear systems taking the strict-feedback form. Adaptive dynamic programming (ADP) and nonlinear output regulation theories are integrated for the first time to compute an adaptive near-optimal tracker without any a priori knowledge of the system dynamics. Fundamentally different from adaptive optimal stabilization problems, the solution to a Hamilton-Jacobi-Bellman (HJB) equation, not necessarily a positive definite function, cannot be approximated through the existing iterative methods. This paper proposes a novel policy iteration technique for solving positive semidefinite HJB equations with rigorous convergence analysis. A two-phase data-driven learning method is developed and implemented online by ADP. The efficacy of the proposed adaptive optimal tracking control methodology is demonstrated via a Van der Pol oscillator with time-varying exogenous signals.

  16. Optimal centralized and decentralized velocity feedback control on a beam

    International Nuclear Information System (INIS)

    Engels, W P; Elliott, S J

    2008-01-01

    This paper considers the optimization of a velocity feedback controller with a collocated force actuator, to minimize the kinetic energy of a simply supported beam. If the beam is excited at a single location, the optimum feedback gain varies with the position of the control system. It is shown that this variation depends partly on the location of the control force relative to the exciting force. If a distributed excitation is assumed, that is random in both time and space, a unique optimum value of the feedback gain can be found for a given control location. The effect of the control location on performance and the optimal feedback gain can then be examined and is found to be limited provided the control locations are not close to the ends of the beam. The optimization can also be performed for a multichannel velocity feedback system. Both a centralized and a decentralized controller are considered. It is shown that the difference in performance between a centralized and a decentralized controller is small, unless the control locations are closely spaced. In this case the centralized controller effectively feeds back a moment proportional to angular velocity as well as a force proportional to a velocity. It is also shown that the optimal feedback gain can be approximated on the basis of a limited model and that similar results can be achieved

  17. Optimal feedback control successfully explains changes in neural modulations during experiments with brain-machine interfaces

    Directory of Open Access Journals (Sweden)

    Miriam eZacksenhouse

    2015-05-01

    Full Text Available Recent experiments with brain-machine-interfaces (BMIs indicate that the extent of neural modulations increased abruptly upon starting to operate the interface, and especially after the monkey stopped moving its hand. In contrast, neural modulations that are correlated with the kinematics of the movement remained relatively unchanged. Here we demonstrate that similar changes are produced by simulated neurons that encode the relevant signals generated by an optimal feedback controller during simulated BMI experiments. The optimal feedback controller relies on state estimation that integrates both visual and proprioceptive feedback with prior estimations from an internal model. The processing required for optimal state estimation and control were conducted in the state-space, and neural recording was simulated by modeling two populations of neurons that encode either only the estimated state or also the control signal. Spike counts were generated as realizations of doubly stochastic Poisson processes with linear tuning curves. The model successfully reconstructs the main features of the kinematics and neural activity during regular reaching movements. Most importantly, the activity of the simulated neurons successfully reproduces the observed changes in neural modulations upon switching to brain control. Further theoretical analysis and simulations indicate that increasing the process noise during normal reaching movement results in similar changes in neural modulations. Thus we conclude that the observed changes in neural modulations during BMI experiments can be attributed to increasing process noise associated with the imperfect BMI filter, and, more directly, to the resulting increase in the variance of the encoded signals associated with state estimation and the required control signal.

  18. Optimal feedback control successfully explains changes in neural modulations during experiments with brain-machine interfaces.

    Science.gov (United States)

    Benyamini, Miri; Zacksenhouse, Miriam

    2015-01-01

    Recent experiments with brain-machine-interfaces (BMIs) indicate that the extent of neural modulations increased abruptly upon starting to operate the interface, and especially after the monkey stopped moving its hand. In contrast, neural modulations that are correlated with the kinematics of the movement remained relatively unchanged. Here we demonstrate that similar changes are produced by simulated neurons that encode the relevant signals generated by an optimal feedback controller during simulated BMI experiments. The optimal feedback controller relies on state estimation that integrates both visual and proprioceptive feedback with prior estimations from an internal model. The processing required for optimal state estimation and control were conducted in the state-space, and neural recording was simulated by modeling two populations of neurons that encode either only the estimated state or also the control signal. Spike counts were generated as realizations of doubly stochastic Poisson processes with linear tuning curves. The model successfully reconstructs the main features of the kinematics and neural activity during regular reaching movements. Most importantly, the activity of the simulated neurons successfully reproduces the observed changes in neural modulations upon switching to brain control. Further theoretical analysis and simulations indicate that increasing the process noise during normal reaching movement results in similar changes in neural modulations. Thus, we conclude that the observed changes in neural modulations during BMI experiments can be attributed to increasing process noise associated with the imperfect BMI filter, and, more directly, to the resulting increase in the variance of the encoded signals associated with state estimation and the required control signal.

  19. Online feedback-controlled renal constant infusion clearances in rats.

    Science.gov (United States)

    Schock-Kusch, Daniel; Shulhevich, Yury; Xie, Qing; Hesser, Juergen; Stsepankou, Dzmitry; Neudecker, Sabine; Friedemann, Jochen; Koenig, Stefan; Heinrich, Ralf; Hoecklin, Friederike; Pill, Johannes; Gretz, Norbert

    2012-08-01

    Constant infusion clearance techniques using exogenous renal markers are considered the gold standard for assessing the glomerular filtration rate. Here we describe a constant infusion clearance method in rats allowing the real-time monitoring of steady-state conditions using an automated closed-loop approach based on the transcutaneous measurement of the renal marker FITC-sinistrin. In order to optimize parameters to reach steady-state conditions as fast as possible, a Matlab-based simulation tool was established. Based on this, a real-time feedback-regulated approach for constant infusion clearance monitoring was developed. This was validated by determining hourly FITC-sinistrin plasma concentrations and the glomerular filtration rate in healthy and unilaterally nephrectomized rats. The transcutaneously assessed FITC-sinistrin fluorescence signal was found to reflect the plasma concentration. Our method allows the precise determination of the onset of steady-state marker concentration. Moreover, the steady state can be monitored and controlled in real time for several hours. This procedure is simple to perform since no urine samples and only one blood sample are required. Thus, we developed a real-time feedback-based system for optimal regulation and monitoring of a constant infusion clearance technique.

  20. Factorization and the synthesis of optimal feedback kernels for differential-delay systems

    Science.gov (United States)

    Milman, Mark M.; Scheid, Robert E.

    1987-01-01

    A combination of ideas from the theories of operator Riccati equations and Volterra factorizations leads to the derivation of a novel, relatively simple set of hyperbolic equations which characterize the optimal feedback kernel for the finite-time regulator problem for autonomous differential-delay systems. Analysis of these equations elucidates the underlying structure of the feedback kernel and leads to the development of fast and accurate numerical methods for its computation. Unlike traditional formulations based on the operator Riccati equation, the gain is characterized by means of classical solutions of the derived set of equations. This leads to the development of approximation schemes which are analogous to what has been accomplished for systems of ordinary differential equations with given initial conditions.

  1. Self-regulation strategy, feedback timing and hemodynamic properties modulate learning in a simulated fMRI neurofeedback environment.

    Science.gov (United States)

    Oblak, Ethan F; Lewis-Peacock, Jarrod A; Sulzer, James S

    2017-07-01

    self-regulation mechanisms prefer different feedback timings, and that these factors can be effectively explored and optimized via simulation prior to deployment in the MRI scanner.

  2. Self-regulation strategy, feedback timing and hemodynamic properties modulate learning in a simulated fMRI neurofeedback environment.

    Directory of Open Access Journals (Sweden)

    Ethan F Oblak

    2017-07-01

    suggest that different self-regulation mechanisms prefer different feedback timings, and that these factors can be effectively explored and optimized via simulation prior to deployment in the MRI scanner.

  3. Self-regulation strategy, feedback timing and hemodynamic properties modulate learning in a simulated fMRI neurofeedback environment

    Science.gov (United States)

    Sulzer, James S.

    2017-01-01

    self-regulation mechanisms prefer different feedback timings, and that these factors can be effectively explored and optimized via simulation prior to deployment in the MRI scanner. PMID:28753639

  4. Output Feedback Adaptive Control of Non-Minimum Phase Systems Using Optimal Control Modification

    Science.gov (United States)

    Nguyen, Nhan; Hashemi, Kelley E.; Yucelen, Tansel; Arabi, Ehsan

    2018-01-01

    This paper describes output feedback adaptive control approaches for non-minimum phase SISO systems with relative degree 1 and non-strictly positive real (SPR) MIMO systems with uniform relative degree 1 using the optimal control modification method. It is well-known that the standard model-reference adaptive control (MRAC) cannot be used to control non-SPR plants to track an ideal SPR reference model. Due to the ideal property of asymptotic tracking, MRAC attempts an unstable pole-zero cancellation which results in unbounded signals for non-minimum phase SISO systems. The optimal control modification can be used to prevent the unstable pole-zero cancellation which results in a stable adaptation of non-minimum phase SISO systems. However, the tracking performance using this approach could suffer if the unstable zero is located far away from the imaginary axis. The tracking performance can be recovered by using an observer-based output feedback adaptive control approach which uses a Luenberger observer design to estimate the state information of the plant. Instead of explicitly specifying an ideal SPR reference model, the reference model is established from the linear quadratic optimal control to account for the non-minimum phase behavior of the plant. With this non-minimum phase reference model, the observer-based output feedback adaptive control can maintain stability as well as tracking performance. However, in the presence of the mismatch between the SPR reference model and the non-minimum phase plant, the standard MRAC results in unbounded signals, whereas a stable adaptation can be achieved with the optimal control modification. An application of output feedback adaptive control for a flexible wing aircraft illustrates the approaches.

  5. Towards Quantum Cybernetics:. Optimal Feedback Control in Quantum Bio Informatics

    Science.gov (United States)

    Belavkin, V. P.

    2009-02-01

    A brief account of the quantum information dynamics and dynamical programming methods for the purpose of optimal control in quantum cybernetics with convex constraints and cońcave cost and bequest functions of the quantum state is given. Consideration is given to both open loop and feedback control schemes corresponding respectively to deterministic and stochastic semi-Markov dynamics of stable or unstable systems. For the quantum feedback control scheme with continuous observations we exploit the separation theorem of filtering and control aspects for quantum stochastic micro-dynamics of the total system. This allows to start with the Belavkin quantum filtering equation and derive the generalized Hamilton-Jacobi-Bellman equation using standard arguments of classical control theory. This is equivalent to a Hamilton-Jacobi equation with an extra linear dissipative term if the control is restricted to only Hamiltonian terms in the filtering equation. A controlled qubit is considered as an example throughout the development of the formalism. Finally, we discuss optimum observation strategies to obtain a pure quantum qubit state from a mixed one.

  6. A stochastic optimal feedforward and feedback control methodology for superagility

    Science.gov (United States)

    Halyo, Nesim; Direskeneli, Haldun; Taylor, Deborah B.

    1992-01-01

    A new control design methodology is developed: Stochastic Optimal Feedforward and Feedback Technology (SOFFT). Traditional design techniques optimize a single cost function (which expresses the design objectives) to obtain both the feedforward and feedback control laws. This approach places conflicting demands on the control law such as fast tracking versus noise atttenuation/disturbance rejection. In the SOFFT approach, two cost functions are defined. The feedforward control law is designed to optimize one cost function, the feedback optimizes the other. By separating the design objectives and decoupling the feedforward and feedback design processes, both objectives can be achieved fully. A new measure of command tracking performance, Z-plots, is also developed. By analyzing these plots at off-nominal conditions, the sensitivity or robustness of the system in tracking commands can be predicted. Z-plots provide an important tool for designing robust control systems. The Variable-Gain SOFFT methodology was used to design a flight control system for the F/A-18 aircraft. It is shown that SOFFT can be used to expand the operating regime and provide greater performance (flying/handling qualities) throughout the extended flight regime. This work was performed under the NASA SBIR program. ICS plans to market the software developed as a new module in its commercial CACSD software package: ACET.

  7. [Leptin and the feedback regulation of body weight].

    Science.gov (United States)

    Wang, X; Ye, G; Sun, J

    1999-09-30

    Body weight may be controlled by a negative feedback loop. Recent studies have identified that the ob gene product, leptin, apparently and exclusively expressed in adipose tissue, is a part of the negative feedback loop. Leptin is proposed to act as an afferent signal in the negative feedback loop to hypothalamus that limiting food-intake, controlling energy homeostasis and regulating the mass of adipose tissue. The dificiency of or resistance to leptin causes severe obesity.

  8. The feed-back regulation of erythropoietin production in healthy humans

    International Nuclear Information System (INIS)

    Klausen, T.

    1998-01-01

    The proposed oxygen-dependent feed-back loop regulation of EPO (erythropoietin) production is mainly supported by data from studies in animals and cell cultures. The feed-back loop and its dependence on oxygen was therefore challenged by studies in healthy humans: Exposure of humans to different levels of acute and continued altitude hypobaria provided evidence for an oxygen dependence of the EPO response. This response is consistent with the proposed feed-back loop regulation of EPO production; Exposure to continued altitude hypobaria demonstrated that the decline in human EPO production is initiated before an EPO-induced erythopoiesis is detectable, and that this decline is related to a concomitant decrease in the haemoglobin-oxygen affinity. Contrary to the feed-back loop, this time-relation indicate that the feed-back regulation of EPO production during continued hypobaric hypoxia is exerted primarily through a decrease in the haemoglobin-oxygen affinity, rather than by the effects of an EPO-stimulated erythropoiesis; Increased circulating levels of the proinflammatory cytokine IL-6 was found in healthy humans during four days of altitude exposure as compared with sea level. The other proinflammatory cytokines IL-1 beta, and TNF alpha remained unchanged, and the increased serum IL-6 did not induce production of c-reactive protein; Comparable circadian variations in human EPO production were shown in sedentary subjects, athletes, and healthy but hypoxaemic subjects. Human EPO production could not be triggered by one hour of high-intensity exercise, whereas longitudinal changes in exercise showed a trend of relation between human EPO production, serum concentration of free testosterone, and indices of body composition. These results have demonstrated and endogenous, probably hormonal, and oxygen-independent regulation of human EPO production, which is at variance with the oxygen dependent feed-back loop regulation of EPO production. Conclusively, the present

  9. Feedback regulation of TGF-β signaling.

    Science.gov (United States)

    Yan, Xiaohua; Xiong, Xiangyang; Chen, Ye-Guang

    2018-01-01

    Transforming growth factor beta (TGF-β) is a multi-functional polypeptide that plays a critical role in regulating a broad range of cellular functions and physiological processes. Signaling is initiated when TGF-β ligands bind to two types of cell membrane receptors with intrinsic Ser/Thr kinase activity and transmitted by the intracellular Smad proteins, which act as transcription factors to regulate gene expression in the nucleus. Although it is relatively simple and straight-forward, this TGF-β/Smad pathway is regulated by various feedback loops at different levels, including the ligand, the receptor, Smads and transcription, and is thus fine-tuned in terms of signaling robustness, duration, specificity, and plasticity. The precise control gives rise to versatile and context-dependent pathophysiological functions. In this review, we firstly give an overview of TGF-β signaling, and then discuss how each step of TGF-β signaling is finely controlled by distinct modes of feedback mechanisms, involving both protein regulators and miRNAs. © The Author 2017. Published by Oxford University Press on behalf of the Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  10. Nonlinear H-ininity state feedback controllers:

    DEFF Research Database (Denmark)

    Cromme, Marc; Møller-Pedersen, Jens; Pagh Petersen, Martin

    1997-01-01

    From a general point of view the state feedback H∞ suboptimal control problem is reasonably well understood. Important problems remain with regard to a priori information of the size of the neighbourhood where the local state feedback H∞ problem is solvable. This problem is solved regionally (sem...... (semiglobally) in this paper, and the obtained control laws are implemented in MAPLE...

  11. Is transverse feedback necessary for the SSC emittance preservation? (Vibration noise analysis and feedback parameters optimization)

    International Nuclear Information System (INIS)

    Parkhomchuk, V.V.; Shiltsev, V.D.

    1993-06-01

    The paper considers the Superconducting Super Collider (SSC) site ground motion measurements as well as data from accelerators worldwide about noises that worsen beam performance. Unacceptably fast emittance growth due to these noises is predicted for the SSC. A transverse feedback system was found to be the only satisfactory alternative to prevent emittance decay. Optimization of the primary feedback parameters was done

  12. Bifurcation Regulations Governed by Delay Self-Control Feedback in a Stochastic Birhythmic System

    Science.gov (United States)

    Ma, Zhidan; Ning, Lijuan

    2017-12-01

    We aim to investigate bifurcation behaviors in a stochastic birhythmic van der Pol (BVDP) system subjected to delay self-control feedback. First, the harmonic approximation is adopted to drive the delay self-control feedback to state variables without delay. Then, Fokker-Planck-Kolmogorov (FPK) equation and stationary probability density function (SPDF) for amplitude are obtained by applying stochastic averaging method. Finally, dynamical scenarios of the change of delay self-control feedback as well as noise that markedly influence bifurcation performance are observed. It is found that: the big feedback strength and delay will suppress the large amplitude limit cycle (LC) while the relatively big noise strength facilitates the large amplitude LC, which imply the proposed regulation strategies are feasible. Interestingly enough, the inner LC is never destroyed due to noise. Furthermore, the validity of analytical results was verified by Monte Carlo simulation of the dynamics.

  13. Feedback regulation between autophagy and PKA.

    Science.gov (United States)

    Torres-Quiroz, Francisco; Filteau, Marie; Landry, Christian R

    2015-01-01

    Protein kinase A (PKA) controls diverse cellular processes and homeostasis in eukaryotic cells. Many processes and substrates of PKA have been described and among them are direct regulators of autophagy. The mechanisms of PKA regulation and how they relate to autophagy remain to be fully understood. We constructed a reporter of PKA activity in yeast to identify genes affecting PKA regulation. The assay systematically measures relative protein-protein interactions between the regulatory and catalytic subunits of the PKA complex in a systematic set of genetic backgrounds. The candidate PKA regulators we identified span multiple processes and molecular functions (autophagy, methionine biosynthesis, TORC signaling, protein acetylation, and DNA repair), which themselves include processes regulated by PKA. These observations suggest the presence of many feedback loops acting through this key regulator. Many of the candidate regulators include genes involved in autophagy, suggesting that not only does PKA regulate autophagy but that autophagy also sends signals back to PKA.

  14. A real-time brain-machine interface combining motor target and trajectory intent using an optimal feedback control design.

    Directory of Open Access Journals (Sweden)

    Maryam M Shanechi

    Full Text Available Real-time brain-machine interfaces (BMI have focused on either estimating the continuous movement trajectory or target intent. However, natural movement often incorporates both. Additionally, BMIs can be modeled as a feedback control system in which the subject modulates the neural activity to move the prosthetic device towards a desired target while receiving real-time sensory feedback of the state of the movement. We develop a novel real-time BMI using an optimal feedback control design that jointly estimates the movement target and trajectory of monkeys in two stages. First, the target is decoded from neural spiking activity before movement initiation. Second, the trajectory is decoded by combining the decoded target with the peri-movement spiking activity using an optimal feedback control design. This design exploits a recursive Bayesian decoder that uses an optimal feedback control model of the sensorimotor system to take into account the intended target location and the sensory feedback in its trajectory estimation from spiking activity. The real-time BMI processes the spiking activity directly using point process modeling. We implement the BMI in experiments consisting of an instructed-delay center-out task in which monkeys are presented with a target location on the screen during a delay period and then have to move a cursor to it without touching the incorrect targets. We show that the two-stage BMI performs more accurately than either stage alone. Correct target prediction can compensate for inaccurate trajectory estimation and vice versa. The optimal feedback control design also results in trajectories that are smoother and have lower estimation error. The two-stage decoder also performs better than linear regression approaches in offline cross-validation analyses. Our results demonstrate the advantage of a BMI design that jointly estimates the target and trajectory of movement and more closely mimics the sensorimotor control system.

  15. Feedback for relatedness and competence : Can feedback in blended learning contribute to optimal rigor, basic needs, and motivation?

    NARCIS (Netherlands)

    Bombaerts, G.; Nickel, P.J.

    2017-01-01

    We inquire how peer and tutor feedback influences students' optimal rigor, basic needs and motivation. We analyze questionnaires from two courses in two subsequent years. We conclude that feedback in blended learning can contribute to rigor and basic needs, but it is not clear from our data what

  16. Tailored parameter optimization methods for ordinary differential equation models with steady-state constraints.

    Science.gov (United States)

    Fiedler, Anna; Raeth, Sebastian; Theis, Fabian J; Hausser, Angelika; Hasenauer, Jan

    2016-08-22

    analysis of the dataset for Raf/MEK/ERK signaling provides novel biological insights regarding the existence of feedback regulation. Many optimization problems considered in systems and computational biology are subject to steady-state constraints. While most optimization methods have convergence problems if these steady-state constraints are highly nonlinear, the methods presented recover the convergence properties of optimizers which can exploit an analytical expression for the parameter-dependent steady state. This renders them an excellent alternative to methods which are currently employed in systems and computational biology.

  17. Spectrum optimization-based chaotification using time-delay feedback control

    International Nuclear Information System (INIS)

    Zhou Jiaxi; Xu Daolin; Zhang Jing; Liu Chunrong

    2012-01-01

    Highlights: ► A time-delay feedback controller is designed for chaotification. ► A spectrum optimization method is proposed to determine chaotification parameters. ► Numerical examples verify the spectrum optimization- based chaotification method. ► Engineering application in line spectrum reconfiguration is demonstrated. - Abstract: In this paper, a spectrum optimization method is developed for chaotification in conjunction with an application in line spectrum reconfiguration. A key performance index (the objective function) based on Fourier spectrum is specially devised with the idea of suppressing spectrum spikes and broadening frequency band. Minimization of the index empowered by a genetic algorithm enables to locate favorable parameters of the time-delay feedback controller, by which a line spectrum of harmonic vibration can be transformed into a broad-band continuous spectrum of chaotic motion. Numerical simulations are carried out to verify the feasibility of the method and to demonstrate its effectiveness of chaotifying a 2-DOFs linear mechanical system.

  18. Control of conducting polymer actuators without physical feedback: simulated feedback control approach with particle swarm optimization

    International Nuclear Information System (INIS)

    Xiang, Xingcan; Mutlu, Rahim; Alici, Gursel; Li, Weihua

    2014-01-01

    Conducting polymer actuators have shown significant potential in articulating micro instruments, manipulation devices, and robotics. However, implementing a feedback control strategy to enhance their positioning ability and accuracy in any application requires a feedback sensor, which is extremely large in size compared to the size of the actuators. Therefore, this paper proposes a new sensorless control scheme without the use of a position feedback sensor. With the help of the system identification technique and particle swarm optimization, the control scheme, which we call the simulated feedback control system, showed a satisfactory command tracking performance for the conducting polymer actuator’s step and dynamic displacement responses, especially under a disturbance, without needing a physical feedback loop, but using a simulated feedback loop. The primary contribution of this study is to propose and experimentally evaluate the simulated feedback control scheme for a class of the conducting polymer actuators known as tri-layer polymer actuators, which can operate both in dry and wet media. This control approach can also be extended to other smart actuators or systems, for which the feedback control based on external sensing is impractical. (paper)

  19. Distributed force feedback in the spinal cord and the regulation of limb mechanics.

    Science.gov (United States)

    Nichols, T Richard

    2018-03-01

    This review is an update on the role of force feedback from Golgi tendon organs in the regulation of limb mechanics during voluntary movement. Current ideas about the role of force feedback are based on modular circuits linking idealized systems of agonists, synergists, and antagonistic muscles. In contrast, force feedback is widely distributed across the muscles of a limb and cannot be understood based on these circuit motifs. Similarly, muscle architecture cannot be understood in terms of idealized systems, since muscles cross multiple joints and axes of rotation and further influence remote joints through inertial coupling. It is hypothesized that distributed force feedback better represents the complex mechanical interactions of muscles, including the stresses in the musculoskeletal network born by muscle articulations, myofascial force transmission, and inertial coupling. Together with the strains of muscle fascicles measured by length feedback from muscle spindle receptors, this integrated proprioceptive feedback represents the mechanical state of the musculoskeletal system. Within the spinal cord, force feedback has excitatory and inhibitory components that coexist in various combinations based on motor task and integrated with length feedback at the premotoneuronal and motoneuronal levels. It is concluded that, in agreement with other investigators, autogenic, excitatory force feedback contributes to propulsion and weight support. It is further concluded that coexistent inhibitory force feedback, together with length feedback, functions to manage interjoint coordination and the mechanical properties of the limb in the face of destabilizing inertial forces and positive force feedback, as required by the accelerations and changing directions of both predator and prey.

  20. Luminosity Optimization Feedback in the SLC

    International Nuclear Information System (INIS)

    1999-01-01

    The luminosity optimization at the SLC has been limited by the precision with which one can measure the micron size beams at the Interaction Point. Ten independent tuning parameters must be adjusted. An automated application has been used to scan each parameter over a significant range and set the minimum beam size as measured with a beam-beam deflection scan. Measurement errors limited the accuracy of this procedure and degraded the resulting luminosity. A new luminosity optimization feedback system has been developed using novel dithering techniques to maximize the luminosity with respect to the 10 parameters, which are adjusted one at a time. Control devices are perturbed around nominal setpoints, while the averaged readout of a digitized luminosity monitor measurement is accumulated for each setting. Results are averaged over many pulses to achieve high precision and then fitted to determine the optimal setting. The dithering itself causes a small loss in luminosity, but the improved optimization is expected to significantly enhance the performance of the SLC. Commissioning results are reported

  1. Relatively slow stochastic gene-state switching in the presence of positive feedback significantly broadens the region of bimodality through stabilizing the uninduced phenotypic state.

    Science.gov (United States)

    Ge, Hao; Wu, Pingping; Qian, Hong; Xie, Xiaoliang Sunney

    2018-03-01

    Within an isogenic population, even in the same extracellular environment, individual cells can exhibit various phenotypic states. The exact role of stochastic gene-state switching regulating the transition among these phenotypic states in a single cell is not fully understood, especially in the presence of positive feedback. Recent high-precision single-cell measurements showed that, at least in bacteria, switching in gene states is slow relative to the typical rates of active transcription and translation. Hence using the lac operon as an archetype, in such a region of operon-state switching, we present a fluctuating-rate model for this classical gene regulation module, incorporating the more realistic operon-state switching mechanism that was recently elucidated. We found that the positive feedback mechanism induces bistability (referred to as deterministic bistability), and that the parameter range for its occurrence is significantly broadened by stochastic operon-state switching. We further show that in the absence of positive feedback, operon-state switching must be extremely slow to trigger bistability by itself. However, in the presence of positive feedback, which stabilizes the induced state, the relatively slow operon-state switching kinetics within the physiological region are sufficient to stabilize the uninduced state, together generating a broadened parameter region of bistability (referred to as stochastic bistability). We illustrate the opposite phenotype-transition rate dependence upon the operon-state switching rates in the two types of bistability, with the aid of a recently proposed rate formula for fluctuating-rate models. The rate formula also predicts a maximal transition rate in the intermediate region of operon-state switching, which is validated by numerical simulations in our model. Overall, our findings suggest a biological function of transcriptional "variations" among genetically identical cells, for the emergence of bistability and

  2. Numerical static state feedback laws for closed-loop singular optimal control

    NARCIS (Netherlands)

    Graaf, de S.C.; Stigter, J.D.; Straten, van G.

    2005-01-01

    Singular and non-singular control trajectories of agricultural and (bio) chemical processes may need to be recalculated from time to time for use in closed-loop optimal control, because of unforeseen changes in state values and noise. This is time consuming. As an alternative, in this paper,

  3. Asymptotic stabilization of nonlinear systems using state feedback

    International Nuclear Information System (INIS)

    D'Attellis, Carlos

    1990-01-01

    This paper studies the design of state-feedback controllers for the stabilization of single-input single-output nonlinear systems x = f(x) + g(x)u, y = h(x). Two approaches for the stabilization problem are given; the asymptotic stability is achieved by means of: a) nonlinear state feedback: two nonlinear feedbacks are used; the first separates the system in a controllable linear part and in the zeros-dynamic part. The second feedback generates an asymptotically stable equilibrium on the manifold where this dynamics evolves; b) nonlinear dynamic feedback: conditions are established under which the system can follow the output of a completely controllable bilinear system which uses bounded controls. This fact enables the system to reach, using bounded controls too, a desired output value in finite time. As this value corresponds to a state that lays in the attraction basin of a stable equilibrium with the same output, the system evolves to that point. The two methods are illustrated by examples. (Author) [es

  4. Optimal estimation and scheduling in aquifer management using the rapid feedback control method

    Science.gov (United States)

    Ghorbanidehno, Hojat; Kokkinaki, Amalia; Kitanidis, Peter K.; Darve, Eric

    2017-12-01

    Management of water resources systems often involves a large number of parameters, as in the case of large, spatially heterogeneous aquifers, and a large number of "noisy" observations, as in the case of pressure observation in wells. Optimizing the operation of such systems requires both searching among many possible solutions and utilizing new information as it becomes available. However, the computational cost of this task increases rapidly with the size of the problem to the extent that textbook optimization methods are practically impossible to apply. In this paper, we present a new computationally efficient technique as a practical alternative for optimally operating large-scale dynamical systems. The proposed method, which we term Rapid Feedback Controller (RFC), provides a practical approach for combined monitoring, parameter estimation, uncertainty quantification, and optimal control for linear and nonlinear systems with a quadratic cost function. For illustration, we consider the case of a weakly nonlinear uncertain dynamical system with a quadratic objective function, specifically a two-dimensional heterogeneous aquifer management problem. To validate our method, we compare our results with the linear quadratic Gaussian (LQG) method, which is the basic approach for feedback control. We show that the computational cost of the RFC scales only linearly with the number of unknowns, a great improvement compared to the basic LQG control with a computational cost that scales quadratically. We demonstrate that the RFC method can obtain the optimal control values at a greatly reduced computational cost compared to the conventional LQG algorithm with small and controllable losses in the accuracy of the state and parameter estimation.

  5. Sensitivity to plant modelling uncertainties in optimal feedback control of sound radiation from a panel

    DEFF Research Database (Denmark)

    Mørkholt, Jakob

    1997-01-01

    Optimal feedback control of broadband sound radiation from a rectangular baffled panel has been investigated through computer simulations. Special emphasis has been put on the sensitivity of the optimal feedback control to uncertainties in the modelling of the system under control.A model...... in terms of a set of radiation filters modelling the radiation dynamics.Linear quadratic feedback control applied to the panel in order to minimise the radiated sound power has then been simulated. The sensitivity of the model based controller to modelling uncertainties when using feedback from actual...

  6. An improved direct feedback linearization technique for transient stability enhancement and voltage regulation of power generators

    Energy Technology Data Exchange (ETDEWEB)

    Kenne, Godpromesse [Laboratoire d' Automatique et d' Informatique Appliquee (LAIA), Departement de Genie Electrique, Universite de Dschang, B.P. 134 Bandjoun, Cameroun; Goma, Raphael; Lamnabhi-Lagarrigue, Francoise [Laboratoire des Signaux et Systemes (L2S), CNRS-SUPELEC, Universite Paris XI, 3 Rue Joliot Curie, 91192 Gif-sur-Yvette (France); Nkwawo, Homere [Departement GEII, Universite Paris XIII, IUT Villetaneuse, 99 Avenue Jean Baptiste Clement, 93430 Villetaneuse (France); Arzande, Amir; Vannier, Jean Claude [Departement Energie, Ecole Superieure d' Electricite-SUPELEC, 3 Rue Joliot Curie, 91192 Gif-sur-Yvette (France)

    2010-09-15

    In this paper, a simple improved direct feedback linearization design method for transient stability and voltage regulation of power systems is discussed. Starting with the classical direct feedback linearization technique currently applied to power systems, an adaptive nonlinear excitation control of synchronous generators is proposed, which is new and effective for engineering. The power angle and mechanical power input are not assumed to be available. The proposed method is based on a standard third-order model of a synchronous generator which requires only information about the physical available measurements of angular speed, active electric power and generator terminal voltage. Experimental results of a practical power system show that fast response, robustness, damping, steady-state and transient stability as well as voltage regulation are all achieved satisfactorily. (author)

  7. Effect of state feedback coupling on the transient performance of voltage source inverters with LC filter

    DEFF Research Database (Denmark)

    Federico, de Bosio; Pastorelli, Michele; Antonio DeSouza Ribeiro, Luiz

    2016-01-01

    State feedback coupling between the capacitor voltage and inductor current deteriorates notably the performance during transients of voltage and current regulators in stand-alone systems based on voltage source inverters. A decoupling technique is proposed, considering the limitations introduced...

  8. Direct output feedback control of discrete-time systems

    International Nuclear Information System (INIS)

    Lin, C.C.; Chung, L.L.; Lu, K.H.

    1993-01-01

    An optimal direct output feedback control algorithm is developed for discrete-time systems with the consideration of time delay in control force action. Optimal constant output feedback gains are obtained through variational process such that certain prescribed quadratic performance index is minimized. Discrete-time control forces are then calculated from the multiplication of output measurements by these pre-calculated feedback gains. According to the proposed algorithm, structural system is assured to remain stable even in the presence of time delay. The number of sensors and controllers may be very small as compared with the dimension of states. Numerical results show that direct velocity feedback control is more sensitive to time delay than state feedback but, is still quite effective in reducing the dynamic responses under earthquake excitation. (author)

  9. Correlations in state space can cause sub-optimal adaptation of optimal feedback control models

    OpenAIRE

    Aprasoff, Jonathan; Donchin, Opher

    2011-01-01

    Control of our movements is apparently facilitated by an adaptive internal model in the cerebellum. It was long thought that this internal model implemented an adaptive inverse model and generated motor commands, but recently many reject that idea in favor of a forward model hypothesis. In theory, the forward model predicts upcoming state during reaching movements so the motor cortex can generate appropriate motor commands. Recent computational models of this process rely on the optimal feedb...

  10. Neuroticism and responsiveness to error feedback: adaptive self-regulation versus affective reactivity.

    Science.gov (United States)

    Robinson, Michael D; Moeller, Sara K; Fetterman, Adam K

    2010-10-01

    Responsiveness to negative feedback has been seen as functional by those who emphasize the value of reflecting on such feedback in self-regulating problematic behaviors. On the other hand, the very same responsiveness has been viewed as dysfunctional by its link to punishment sensitivity and reactivity. The present 4 studies, involving 203 undergraduate participants, sought to reconcile such discrepant views in the context of the trait of neuroticism. In cognitive tasks, individuals were given error feedback when they made mistakes. It was found that greater tendencies to slow down following error feedback were associated with higher levels of accuracy at low levels of neuroticism but lower levels of accuracy at high levels of neuroticism. Individual differences in neuroticism thus appear crucial in understanding whether behavioral alterations following negative feedback reflect proactive versus reactive mechanisms and processes. Implications for understanding the processing basis of neuroticism and adaptive self-regulation are discussed.

  11. Hypothalamic carnitine metabolism integrates nutrient and hormonal feedback to regulate energy homeostasis.

    Science.gov (United States)

    Stark, Romana; Reichenbach, Alex; Andrews, Zane B

    2015-12-15

    The maintenance of energy homeostasis requires the hypothalamic integration of nutrient feedback cues, such as glucose, fatty acids, amino acids, and metabolic hormones such as insulin, leptin and ghrelin. Although hypothalamic neurons are critical to maintain energy homeostasis research efforts have focused on feedback mechanisms in isolation, such as glucose alone, fatty acids alone or single hormones. However this seems rather too simplistic considering the range of nutrient and endocrine changes associated with different metabolic states, such as starvation (negative energy balance) or diet-induced obesity (positive energy balance). In order to understand how neurons integrate multiple nutrient or hormonal signals, we need to identify and examine potential intracellular convergence points or common molecular targets that have the ability to sense glucose, fatty acids, amino acids and hormones. In this review, we focus on the role of carnitine metabolism in neurons regulating energy homeostasis. Hypothalamic carnitine metabolism represents a novel means for neurons to facilitate and control both nutrient and hormonal feedback. In terms of nutrient regulation, carnitine metabolism regulates hypothalamic fatty acid sensing through the actions of CPT1 and has an underappreciated role in glucose sensing since carnitine metabolism also buffers mitochondrial matrix levels of acetyl-CoA, an allosteric inhibitor of pyruvate dehydrogenase and hence glucose metabolism. Studies also show that hypothalamic CPT1 activity also controls hormonal feedback. We hypothesis that hypothalamic carnitine metabolism represents a key molecular target that can concurrently integrate nutrient and hormonal information, which is critical to maintain energy homeostasis. We also suggest this is relevant to broader neuroendocrine research as it predicts that hormonal signaling in the brain varies depending on current nutrient status. Indeed, the metabolic action of ghrelin, leptin or insulin

  12. Multivariable Feedback Control of Nuclear Reactors

    Directory of Open Access Journals (Sweden)

    Rune Moen

    1982-07-01

    Full Text Available Multivariable feedback control has been adapted for optimal control of the spatial power distribution in nuclear reactor cores. Two design techniques, based on the theory of automatic control, were developed: the State Variable Feedback (SVF is an application of the linear optimal control theory, and the Multivariable Frequency Response (MFR is based on a generalization of the traditional frequency response approach to control system design.

  13. Self-regulated learning: A key learning effect of feedback in a ...

    African Journals Online (AJOL)

    Background. Problem-based learning (PBL) has been adopted across many health professions training institutions. Small-group student tutorials are a major component of PBL. Facilitator feedback during a tutorial is a key activity to promote self-regulated learning. Objective. To explore ways in which students use feedback ...

  14. Risk-sensitive optimal feedback control accounts for sensorimotor behavior under uncertainty.

    Directory of Open Access Journals (Sweden)

    Arne J Nagengast

    2010-07-01

    Full Text Available Many aspects of human motor behavior can be understood using optimality principles such as optimal feedback control. However, these proposed optimal control models are risk-neutral; that is, they are indifferent to the variability of the movement cost. Here, we propose the use of a risk-sensitive optimal controller that incorporates movement cost variance either as an added cost (risk-averse controller or as an added value (risk-seeking controller to model human motor behavior in the face of uncertainty. We use a sensorimotor task to test the hypothesis that subjects are risk-sensitive. Subjects controlled a virtual ball undergoing Brownian motion towards a target. Subjects were required to minimize an explicit cost, in points, that was a combination of the final positional error of the ball and the integrated control cost. By testing subjects on different levels of Brownian motion noise and relative weighting of the position and control cost, we could distinguish between risk-sensitive and risk-neutral control. We show that subjects change their movement strategy pessimistically in the face of increased uncertainty in accord with the predictions of a risk-averse optimal controller. Our results suggest that risk-sensitivity is a fundamental attribute that needs to be incorporated into optimal feedback control models.

  15. MicroRNA-Mediated Positive Feedback Loop and Optimized Bistable Switch in a Cancer Network Involving miR-17-92

    Science.gov (United States)

    Li, Yichen; Li, Yumin; Zhang, Hui; Chen, Yong

    2011-01-01

    MicroRNAs (miRNAs) are small, noncoding RNAs that play an important role in many key biological processes, including development, cell differentiation, the cell cycle and apoptosis, as central post-transcriptional regulators of gene expression. Recent studies have shown that miRNAs can act as oncogenes and tumor suppressors depending on the context. The present work focuses on the physiological significance of miRNAs and their role in regulating the switching behavior. We illustrate an abstract model of the Myc/E2F/miR-17-92 network presented by Aguda et al. (2008), which is composed of coupling between the E2F/Myc positive feedback loops and the E2F/Myc/miR-17-92 negative feedback loop. By systematically analyzing the network in close association with plausible experimental parameters, we show that, in the presence of miRNAs, the system bistability emerges from the system, with a bistable switch and a one-way switch presented by Aguda et al. instead of a single one-way switch. Moreover, the miRNAs can optimize the switching process. The model produces a diverse array of response-signal behaviors in response to various potential regulating scenarios. The model predicts that this transition exists, one from cell death or the cancerous phenotype directly to cell quiescence, due to the existence of miRNAs. It was also found that the network involving miR-17-92 exhibits high noise sensitivity due to a positive feedback loop and also maintains resistance to noise from a negative feedback loop. PMID:22022595

  16. CLUMPY DISKS AS A TESTBED FOR FEEDBACK-REGULATED GALAXY FORMATION

    Energy Technology Data Exchange (ETDEWEB)

    Mayer, Lucio; Tamburello, Valentina [Center for Theoretical Astrophysics and Cosmology, Institute for Computational Science, University of Zurich, Winterthurerstrasse 190, CH-8057 Zürich (Switzerland); Lupi, Alessandro; Madau, Piero [Institut d’Astrophysique de Paris, Sorbonne Universités, UPMC Univ Paris 6 et CNRS, UMR 7095, 98 bis bd Arago, F-75014 Paris (France); Keller, Ben; Wadsley, James [Department of Physics and Astronomy, McMaster University, Hamilton, ON L8S 4M1 (Canada)

    2016-10-10

    We study the dependence of fragmentation in massive gas-rich galaxy disks at z >1 on stellar feedback schemes and hydrodynamical solvers, employing the GASOLINE2 SPH code and the lagrangian mesh-less code GIZMO in finite mass mode. Non-cosmological galaxy disk runs with the standard delayed-cooling blastwave feedback are compared with runs adopting a new superbubble feedback, which produces winds by modeling the detailed physics of supernova-driven bubbles and leads to efficient self-regulation of star formation. We find that, with blastwave feedback, massive star-forming clumps form in comparable number and with very similar masses in GASOLINE2 and GIZMO. Typical clump masses are in the range 10{sup 7}–10{sup 8} M {sub ⊙}, lower than in most previous works, while giant clumps with masses above 10{sup 9} M {sub ⊙} are exceedingly rare. By contrast, superbubble feedback does not produce massive star-forming bound clumps as galaxies never undergo a phase of violent disk instability. In this scheme, only sporadic, unbound star-forming overdensities lasting a few tens of Myr can arise, triggered by non-linear perturbations from massive satellite companions. We conclude that there is severe tension between explaining massive star-forming clumps observed at z >1 primarily as the result of disk fragmentation driven by gravitational instability and the prevailing view of feedback-regulated galaxy formation. The link between disk stability and star formation efficiency should thus be regarded as a key testing ground for galaxy formation theory.

  17. Dynamic imperfections and optimized feedback design in the Compact Linear Collider main linac

    Directory of Open Access Journals (Sweden)

    Peder Eliasson

    2008-05-01

    Full Text Available The Compact Linear Collider (CLIC main linac is sensitive to dynamic imperfections such as element jitter, injected beam jitter, and ground motion. These effects cause emittance growth that, in case of ground motion, has to be counteracted by a trajectory feedback system. The feedback system itself will, due to jitter effects and imperfect beam position monitors (BPMs, indirectly cause emittance growth. Fast and accurate simulations of both the direct and indirect effects are desirable, but due to the many elements of the CLIC main linac, simulations may become very time consuming. In this paper, an efficient way of simulating linear (or nearly linear dynamic effects is described. The method is also shown to facilitate the analytic determination of emittance growth caused by the different dynamic imperfections while using a trajectory feedback system. Emittance growth expressions are derived for quadrupole, accelerating structure, and beam jitter, for ground motion, and for noise in the feedback BPMs. Finally, it is shown how the method can be used to design a feedback system that is optimized for the optics of the machine and the ground motion spectrum of the particular site. This feedback system gives an emittance growth rate that is approximately 10 times lower than that of traditional trajectory feedbacks. The robustness of the optimized feedback system is studied for a number of additional imperfections, e.g., dipole corrector imperfections and faulty knowledge about the machine optics, with promising results.

  18. Dynamic imperfections and optimized feedback design in the Compact Linear Collider main linac

    Science.gov (United States)

    Eliasson, Peder

    2008-05-01

    The Compact Linear Collider (CLIC) main linac is sensitive to dynamic imperfections such as element jitter, injected beam jitter, and ground motion. These effects cause emittance growth that, in case of ground motion, has to be counteracted by a trajectory feedback system. The feedback system itself will, due to jitter effects and imperfect beam position monitors (BPMs), indirectly cause emittance growth. Fast and accurate simulations of both the direct and indirect effects are desirable, but due to the many elements of the CLIC main linac, simulations may become very time consuming. In this paper, an efficient way of simulating linear (or nearly linear) dynamic effects is described. The method is also shown to facilitate the analytic determination of emittance growth caused by the different dynamic imperfections while using a trajectory feedback system. Emittance growth expressions are derived for quadrupole, accelerating structure, and beam jitter, for ground motion, and for noise in the feedback BPMs. Finally, it is shown how the method can be used to design a feedback system that is optimized for the optics of the machine and the ground motion spectrum of the particular site. This feedback system gives an emittance growth rate that is approximately 10 times lower than that of traditional trajectory feedbacks. The robustness of the optimized feedback system is studied for a number of additional imperfections, e.g., dipole corrector imperfections and faulty knowledge about the machine optics, with promising results.

  19. Computationally efficient design of optimal output feedback strategies for controllable passive damping devices

    International Nuclear Information System (INIS)

    Kamalzare, Mahmoud; Johnson, Erik A; Wojtkiewicz, Steven F

    2014-01-01

    Designing control strategies for smart structures, such as those with semiactive devices, is complicated by the nonlinear nature of the feedback control, secondary clipping control and other additional requirements such as device saturation. The usual design approach resorts to large-scale simulation parameter studies that are computationally expensive. The authors have previously developed an approach for state-feedback semiactive clipped-optimal control design, based on a nonlinear Volterra integral equation that provides for the computationally efficient simulation of such systems. This paper expands the applicability of the approach by demonstrating that it can also be adapted to accommodate more realistic cases when, instead of full state feedback, only a limited set of noisy response measurements is available to the controller. This extension requires incorporating a Kalman filter (KF) estimator, which is linear, into the nominal model of the uncontrolled system. The efficacy of the approach is demonstrated by a numerical study of a 100-degree-of-freedom frame model, excited by a filtered Gaussian random excitation, with noisy acceleration sensor measurements to determine the semiactive control commands. The results show that the proposed method can improve computational efficiency by more than two orders of magnitude relative to a conventional solver, while retaining a comparable level of accuracy. Further, the proposed approach is shown to be similarly efficient for an extensive Monte Carlo simulation to evaluate the effects of sensor noise levels and KF tuning on the accuracy of the response. (paper)

  20. Optimization of an M/M/1/N Feedback Queue with Retention of Reneged Customers

    Directory of Open Access Journals (Sweden)

    Rakesh Kumar

    2014-01-01

    Full Text Available Customer impatience has become a threat to the business world. Firms employ various customer retention strategies to retain their impatient (or reneged customers. Customer retention mechanisms may help to retain some or all impatient customers. Further, due to unsatisfactory service, customers may rejoin a queue immediately after departure. Such cases are referred to as feedback customers. Kumar and Sharma take this situation into account and study an M/M/1/N feedback queuing system with retention of reneged customers. They obtain only a steady-state solution for this model. In this paper, we extend the work of Kumar and Sharma by performing an economic analysis of the model. We develop a model for the costs incurred and perform the appropriate optimization. The optimum system capacity and optimum service rate are obtained. (original abstract

  1. Student conceptions of feedback: Impact on self-regulation, self-efficacy, and academic achievement.

    Science.gov (United States)

    Brown, Gavin T L; Peterson, Elizabeth R; Yao, Esther S

    2016-12-01

    Lecturers give feedback on assessed work in the hope that students will take it on board and use it to help regulate their learning for the next assessment. However, little is known about how students' conceptions of feedback relate to students' self-regulated learning and self-efficacy beliefs and academic performance. This study explores student beliefs about the role and purpose of feedback and the relationship of those beliefs to self-reported self-regulation and self-efficacy, and achievement. A total of 278 university students in a general education course on learning theory and approaches in a research-intensive university. Self-reported survey responses for students' conceptions of feedback (SCoF), self-regulation (SRL), academic self-efficacy (ASE), and Grade Point Average (GPA) were evaluated first with confirmatory factor analysis and then interlinked in a structural equation model. Three SCoF factors predicted SRL and/or GPA. The SCoF factor 'I use feedback' had positive associations with SRL (β = .44), GPA (β = .45), and ASE (β = .15). The SCoF factors 'tutor/marker comments' and 'peers help' both had negative relations to GPA (β = -.41 and -.16, respectively). 'Peers help' had a positive connection to SRL (β = .21). ASE itself made a small contribution to overall GPA (β = .16), while SRL had no statistically significant relation to GPA. The model indicates the centrality of believing that feedback exists to guide next steps in learning and thus contributes to SRL, ASE, and increased GPA. © 2016 The British Psychological Society.

  2. Extremum-Seeking Control and Applications A Numerical Optimization-Based Approach

    CERN Document Server

    Zhang, Chunlei

    2012-01-01

    Extremum seeking control tracks a varying maximum or minimum in a performance function such as a cost. It attempts to determine the optimal performance of a control system as it operates, thereby reducing downtime and the need for system analysis. Extremum Seeking Control and Applications is divided into two parts. In the first, the authors review existing analog optimization based extremum seeking control including gradient, perturbation and sliding mode based control designs. They then propose a novel numerical optimization based extremum seeking control based on optimization algorithms and state regulation. This control design is developed for simple linear time-invariant systems and then extended for a class of feedback linearizable nonlinear systems. The two main optimization algorithms – line search and trust region methods – are analyzed for robustness. Finite-time and asymptotic state regulators are put forward for linear and nonlinear systems respectively. Further design flexibility is achieved u...

  3. Optimal control of transverse mode coupling instability based on the two particle model

    International Nuclear Information System (INIS)

    Ogata, Atsushi

    1985-01-01

    The optimal regulator design technique is applied to asymptotically stabilize the transverse mode coupling instability of a storage ring. The state equations are based on the two particle model. These are a pair of equation sets, one for the first and one for the second half of the synchrotron phase. Each set consists of first-order difference equations in vector-matrix form, with time step equal to the revolution time of the ring. Solution of the discrete Riccati equation gives the optimal gain matrix of the transverse feedback. Computer simulations are carried out to verify its effectiveness. Some modifications necessary to apply it to the real accelerator operation are made. The old methods, the classical output feedback and the reactive feedback, are interpreted from the viewpoint of the optimal control. (orig.)

  4. Optimal design of tweezer control for chimera states

    Science.gov (United States)

    Omelchenko, Iryna; Omel'chenko, Oleh E.; Zakharova, Anna; Schöll, Eckehard

    2018-01-01

    Chimera states are complex spatio-temporal patterns which consist of coexisting domains of spatially coherent and incoherent dynamics in systems of coupled oscillators. In small networks, chimera states usually exhibit short lifetimes and erratic drifting of the spatial position of the incoherent domain. A tweezer feedback control scheme can stabilize and fix the position of chimera states. We analyze the action of the tweezer control in small nonlocally coupled networks of Van der Pol and FitzHugh-Nagumo oscillators, and determine the ranges of optimal control parameters. We demonstrate that the tweezer control scheme allows for stabilization of chimera states with different shapes, and can be used as an instrument for controlling the coherent domains size, as well as the maximum average frequency difference of the oscillators.

  5. Stochastic Optimized Relevance Feedback Particle Swarm Optimization for Content Based Image Retrieval

    Directory of Open Access Journals (Sweden)

    Muhammad Imran

    2014-01-01

    Full Text Available One of the major challenges for the CBIR is to bridge the gap between low level features and high level semantics according to the need of the user. To overcome this gap, relevance feedback (RF coupled with support vector machine (SVM has been applied successfully. However, when the feedback sample is small, the performance of the SVM based RF is often poor. To improve the performance of RF, this paper has proposed a new technique, namely, PSO-SVM-RF, which combines SVM based RF with particle swarm optimization (PSO. The aims of this proposed technique are to enhance the performance of SVM based RF and also to minimize the user interaction with the system by minimizing the RF number. The PSO-SVM-RF was tested on the coral photo gallery containing 10908 images. The results obtained from the experiments showed that the proposed PSO-SVM-RF achieved 100% accuracy in 8 feedback iterations for top 10 retrievals and 80% accuracy in 6 iterations for 100 top retrievals. This implies that with PSO-SVM-RF technique high accuracy rate is achieved at a small number of iterations.

  6. Functional observer and state feedback

    International Nuclear Information System (INIS)

    Zhang, S.Y.

    1986-01-01

    In this paper, we show the relation between state space approach and transfer function approach for functional observer and state feedback design. Two approaches can be transformed into each other, based on this result. More importantly, we find that the state space approach introduces some severe, unnecessary restrictions in solving the problem. The restrictions are, however, reduced to be a trivial condition in transfer function approach. It is believed that the result presented in this paper will be useful in developing both approaches, and motivate some new results for solving the problem

  7. The effect of regulation feedback in a computer-based formative assessment on information problem solving

    NARCIS (Netherlands)

    Timmers, Caroline; Walraven, Amber; Veldkamp, Bernard P.

    2015-01-01

    This study examines the effect of regulation feedback in a computer-based formative assessment in the context of searching for information online. Fifty 13-year-old students completed two randomly selected assessment tasks, receiving automated regulation feedback between them. Student performance

  8. Initial state regulation of investor-owned utilities

    International Nuclear Information System (INIS)

    Savitski, D.W.

    2001-01-01

    This paper examines state initiation of public service (or utility) commission regulation of investor-owned utilities (IOUs) using an economic theory of regulation. The decision to regulate IOUs is assumed to have depended on the strength of competing interest groups, e.g. consumers and producers, and on institutional factors, e.g. whether commissioners were appointed or elected. Regulators, which then had jurisdiction over IOU rates, are assumed to have been optimizing agents. The potential benefits of regulation, in turn, translated into pressure to initiate regulation. To test this, a hazard model is applied to state-level data. On the demand side of the regulation market, the distribution of federal power and population density were unrelated, while a set of time dummies was positively related to the probability that a state initiated regulation. On the supply side, the fraction of the population that was urban and whether the governor was Republican or not were positively and negatively related to this probability

  9. Optimizing the feedback control of Galvo scanners for laser manufacturing systems

    Science.gov (United States)

    Mirtchev, Theodore; Weeks, Robert; Minko, Sergey

    2010-06-01

    This paper summarizes the factors that limit the performance of moving-magnet galvo scanners driven by closed-loop digital servo amplifiers: torsional resonances, drifts, nonlinearities, feedback noise and friction. Then it describes a detailed Simulink® simulator that takes into account these factors and can be used to automatically tune the controller for best results with given galvo type and trajectory patterns. It allows for rapid testing of different control schemes, for instance combined position/velocity PID loops and displays the corresponding output in terms of torque, angular position and feedback sensor signal. The tool is configurable and can either use a dynamical state-space model of galvo's open-loop response, or can import the experimentally measured frequency domain transfer function. Next a drive signal digital pre-filtering technique is discussed. By performing a real-time Fourier analysis of the raw command signal it can be pre-warped to minimize all harmonics around the torsional resonances while boosting other non-resonant high frequencies. The optimized waveform results in much smaller overshoot and better settling time. Similar performance gain cannot be extracted from the servo controller alone.

  10. ORACLS- OPTIMAL REGULATOR ALGORITHMS FOR THE CONTROL OF LINEAR SYSTEMS (CDC VERSION)

    Science.gov (United States)

    Armstrong, E. S.

    1994-01-01

    This control theory design package, called Optimal Regulator Algorithms for the Control of Linear Systems (ORACLS), was developed to aid in the design of controllers and optimal filters for systems which can be modeled by linear, time-invariant differential and difference equations. Optimal linear quadratic regulator theory, currently referred to as the Linear-Quadratic-Gaussian (LQG) problem, has become the most widely accepted method of determining optimal control policy. Within this theory, the infinite duration time-invariant problems, which lead to constant gain feedback control laws and constant Kalman-Bucy filter gains for reconstruction of the system state, exhibit high tractability and potential ease of implementation. A variety of new and efficient methods in the field of numerical linear algebra have been combined into the ORACLS program, which provides for the solution to time-invariant continuous or discrete LQG problems. The ORACLS package is particularly attractive to the control system designer because it provides a rigorous tool for dealing with multi-input and multi-output dynamic systems in both continuous and discrete form. The ORACLS programming system is a collection of subroutines which can be used to formulate, manipulate, and solve various LQG design problems. The ORACLS program is constructed in a manner which permits the user to maintain considerable flexibility at each operational state. This flexibility is accomplished by providing primary operations, analysis of linear time-invariant systems, and control synthesis based on LQG methodology. The input-output routines handle the reading and writing of numerical matrices, printing heading information, and accumulating output information. The basic vector-matrix operations include addition, subtraction, multiplication, equation, norm construction, tracing, transposition, scaling, juxtaposition, and construction of null and identity matrices. The analysis routines provide for the following

  11. Nonlinear H-infinity State Feedback Controllers: Computation of Valid Region

    DEFF Research Database (Denmark)

    Pedersen, Michael; Møller-Pedersen, J.; Pagh Petersen, M.

    1996-01-01

    "From a general point of view the state feedback QTR H-infinitysuboptimal control probelm is reasonable well-understood. Inportantproblems remain with regard to a priori information of the size of theneighbourhood where the local state feedback QTR H-infinityproblem is solvable, and with regard t...

  12. Swarm intelligence algorithms for integrated optimization of piezoelectric actuator and sensor placement and feedback gains

    International Nuclear Information System (INIS)

    Dutta, Rajdeep; Ganguli, Ranjan; Mani, V

    2011-01-01

    Swarm intelligence algorithms are applied for optimal control of flexible smart structures bonded with piezoelectric actuators and sensors. The optimal locations of actuators/sensors and feedback gain are obtained by maximizing the energy dissipated by the feedback control system. We provide a mathematical proof that this system is uncontrollable if the actuators and sensors are placed at the nodal points of the mode shapes. The optimal locations of actuators/sensors and feedback gain represent a constrained non-linear optimization problem. This problem is converted to an unconstrained optimization problem by using penalty functions. Two swarm intelligence algorithms, namely, Artificial bee colony (ABC) and glowworm swarm optimization (GSO) algorithms, are considered to obtain the optimal solution. In earlier published research, a cantilever beam with one and two collocated actuator(s)/sensor(s) was considered and the numerical results were obtained by using genetic algorithm and gradient based optimization methods. We consider the same problem and present the results obtained by using the swarm intelligence algorithms ABC and GSO. An extension of this cantilever beam problem with five collocated actuators/sensors is considered and the numerical results obtained by using the ABC and GSO algorithms are presented. The effect of increasing the number of design variables (locations of actuators and sensors and gain) on the optimization process is investigated. It is shown that the ABC and GSO algorithms are robust and are good choices for the optimization of smart structures

  13. Effect of State Feedback Coupling and System Delays on the Transient Performance of Stand-Alone VSI with LC Output Filter

    DEFF Research Database (Denmark)

    Federico, de Bosio; de Sousa Ribeiro, Luiz Antonio; Freijedo Fernandez, Francisco Daniel

    2016-01-01

    The influence of state feedback coupling in the dynamics performance of power converters for stand-alone microgrids is investigated. Computation and PWM delays are the main factors that limit the achievable bandwidth of current regulators in digital implementations. In particular, the performance...... of state feedback decoupling is degraded because of these delays. Two decoupling techniques to improve the transient response of the system are investigated, named non-ideal and ideal capacitor voltage decoupling respectively. In particular, the latter solution consists in leading the capacitor voltage...... on the state feedback decoupling path in order to compensate for system delays. Practical implementation issues are discussed with reference to both the decoupling techniques. A design methodology for the voltage loop, that considers the closed loop transfer functions developed for the inner loop, is also...

  14. System state estimation and optimal energy control framework for multicell lithium-ion battery system

    International Nuclear Information System (INIS)

    Wei, Jingwen; Dong, Guangzhong; Chen, Zonghai; Kang, Yu

    2017-01-01

    Highlights: • Employed a dual-scale EKF based estimator for in-pack cells’ SOC values. • Proposed a two-stage hybrid state-feedback and output-feedback equalization algorithm. • A switchable balance current mode is designed in the equalization topology. • Verified the performance of proposed method under two conditions. - Abstract: Cell variations caused by the inevitable inconsistency during manufacture and use of battery cells have significant impacts on battery capacity, security and durability for battery energy storage systems. Thus, the battery equalization systems are essentially required to reduce variations of in-pack cells and increase battery pack capability. In order to protect all in-pack cells from damaging, estimate battery state and reduce variations, a system state estimation and energy optimal control framework for multicell lithium-ion battery system is proposed. The state-of-charge (SOC) values of all in-pack cells are firstly estimated using a dual-scale extended Kalman filtering (EKF) to improve estimation accuracy and reduce computation simultaneously. These estimated SOC values provide specific details of battery system, which cannot only be used to protect cells from over-charging/over-discharging, but also be employed to design state-feedback controller for battery equalization system. A two-stage hybrid state-feedback and output-feedback equalization algorithm is proposed. The state-feedback controller is firstly employed for coarse-grained adjustment to reduce equalization time cost with large current. However, due to the inevitable SOC estimation errors, the output-feedback controller is then used for fine-grained adjustment with trickle current. Experimental results show that the proposed framework can provide an effectively estimation and energy control for multicell battery systems. Finally, the implementation of the proposed method is further discussed for the real applications.

  15. Neural network-based optimal adaptive output feedback control of a helicopter UAV.

    Science.gov (United States)

    Nodland, David; Zargarzadeh, Hassan; Jagannathan, Sarangapani

    2013-07-01

    Helicopter unmanned aerial vehicles (UAVs) are widely used for both military and civilian operations. Because the helicopter UAVs are underactuated nonlinear mechanical systems, high-performance controller design for them presents a challenge. This paper introduces an optimal controller design via an output feedback for trajectory tracking of a helicopter UAV, using a neural network (NN). The output-feedback control system utilizes the backstepping methodology, employing kinematic and dynamic controllers and an NN observer. The online approximator-based dynamic controller learns the infinite-horizon Hamilton-Jacobi-Bellman equation in continuous time and calculates the corresponding optimal control input by minimizing a cost function, forward-in-time, without using the value and policy iterations. Optimal tracking is accomplished by using a single NN utilized for the cost function approximation. The overall closed-loop system stability is demonstrated using Lyapunov analysis. Finally, simulation results are provided to demonstrate the effectiveness of the proposed control design for trajectory tracking.

  16. Network feedback regulates motor output across a range of modulatory neuron activity.

    Science.gov (United States)

    Spencer, Robert M; Blitz, Dawn M

    2016-06-01

    Modulatory projection neurons alter network neuron synaptic and intrinsic properties to elicit multiple different outputs. Sensory and other inputs elicit a range of modulatory neuron activity that is further shaped by network feedback, yet little is known regarding how the impact of network feedback on modulatory neurons regulates network output across a physiological range of modulatory neuron activity. Identified network neurons, a fully described connectome, and a well-characterized, identified modulatory projection neuron enabled us to address this issue in the crab (Cancer borealis) stomatogastric nervous system. The modulatory neuron modulatory commissural neuron 1 (MCN1) activates and modulates two networks that generate rhythms via different cellular mechanisms and at distinct frequencies. MCN1 is activated at rates of 5-35 Hz in vivo and in vitro. Additionally, network feedback elicits MCN1 activity time-locked to motor activity. We asked how network activation, rhythm speed, and neuron activity levels are regulated by the presence or absence of network feedback across a physiological range of MCN1 activity rates. There were both similarities and differences in responses of the two networks to MCN1 activity. Many parameters in both networks were sensitive to network feedback effects on MCN1 activity. However, for most parameters, MCN1 activity rate did not determine the extent to which network output was altered by the addition of network feedback. These data demonstrate that the influence of network feedback on modulatory neuron activity is an important determinant of network output and feedback can be effective in shaping network output regardless of the extent of network modulation. Copyright © 2016 the American Physiological Society.

  17. Animal personality and state-behaviour feedbacks: a review and guide for empiricists.

    Science.gov (United States)

    Sih, Andrew; Mathot, Kimberley J; Moirón, María; Montiglio, Pierre-Olivier; Wolf, Max; Dingemanse, Niels J

    2015-01-01

    An exciting area in behavioural ecology focuses on understanding why animals exhibit consistent among-individual differences in behaviour (animal personalities). Animal personality has been proposed to emerge as an adaptation to individual differences in state variables, leading to the question of why individuals differ consistently in state. Recent theory emphasizes the role that positive feedbacks between state and behaviour can play in producing consistent among-individual covariance between state and behaviour, hence state-dependent personality. We review the role of feedbacks in recent models of adaptive personalities, and provide guidelines for empirical testing of model assumptions and predictions. We discuss the importance of the mediating effects of ecology on these feedbacks, and provide a roadmap for including state-behaviour feedbacks in behavioural ecology research. Copyright © 2014 Elsevier Ltd. All rights reserved.

  18. Object discrimination using optimized multi-frequency auditory cross-modal haptic feedback.

    Science.gov (United States)

    Gibson, Alison; Artemiadis, Panagiotis

    2014-01-01

    As the field of brain-machine interfaces and neuro-prosthetics continues to grow, there is a high need for sensor and actuation mechanisms that can provide haptic feedback to the user. Current technologies employ expensive, invasive and often inefficient force feedback methods, resulting in an unrealistic solution for individuals who rely on these devices. This paper responds through the development, integration and analysis of a novel feedback architecture where haptic information during the neural control of a prosthetic hand is perceived through multi-frequency auditory signals. Through representing force magnitude with volume and force location with frequency, the feedback architecture can translate the haptic experiences of a robotic end effector into the alternative sensory modality of sound. Previous research with the proposed cross-modal feedback method confirmed its learnability, so the current work aimed to investigate which frequency map (i.e. frequency-specific locations on the hand) is optimal in helping users distinguish between hand-held objects and tasks associated with them. After short use with the cross-modal feedback during the electromyographic (EMG) control of a prosthetic hand, testing results show that users are able to use audial feedback alone to discriminate between everyday objects. While users showed adaptation to three different frequency maps, the simplest map containing only two frequencies was found to be the most useful in discriminating between objects. This outcome provides support for the feasibility and practicality of the cross-modal feedback method during the neural control of prosthetics.

  19. On Optimal Feedback Control for Stationary Linear Systems

    International Nuclear Information System (INIS)

    Russell, David L.

    2010-01-01

    We study linear-quadratic optimal control problems for finite dimensional stationary linear systems AX+BU=Z with output Y=CX+DU from the viewpoint of linear feedback solution. We interpret solutions in relation to system robustness with respect to disturbances Z and relate them to nonlinear matrix equations of Riccati type and eigenvalue-eigenvector problems for the corresponding Hamiltonian system. Examples are included along with an indication of extensions to continuous, i.e., infinite dimensional, systems, primarily of elliptic type.

  20. ORACLS- OPTIMAL REGULATOR ALGORITHMS FOR THE CONTROL OF LINEAR SYSTEMS (DEC VAX VERSION)

    Science.gov (United States)

    Frisch, H.

    1994-01-01

    This control theory design package, called Optimal Regulator Algorithms for the Control of Linear Systems (ORACLS), was developed to aid in the design of controllers and optimal filters for systems which can be modeled by linear, time-invariant differential and difference equations. Optimal linear quadratic regulator theory, currently referred to as the Linear-Quadratic-Gaussian (LQG) problem, has become the most widely accepted method of determining optimal control policy. Within this theory, the infinite duration time-invariant problems, which lead to constant gain feedback control laws and constant Kalman-Bucy filter gains for reconstruction of the system state, exhibit high tractability and potential ease of implementation. A variety of new and efficient methods in the field of numerical linear algebra have been combined into the ORACLS program, which provides for the solution to time-invariant continuous or discrete LQG problems. The ORACLS package is particularly attractive to the control system designer because it provides a rigorous tool for dealing with multi-input and multi-output dynamic systems in both continuous and discrete form. The ORACLS programming system is a collection of subroutines which can be used to formulate, manipulate, and solve various LQG design problems. The ORACLS program is constructed in a manner which permits the user to maintain considerable flexibility at each operational state. This flexibility is accomplished by providing primary operations, analysis of linear time-invariant systems, and control synthesis based on LQG methodology. The input-output routines handle the reading and writing of numerical matrices, printing heading information, and accumulating output information. The basic vector-matrix operations include addition, subtraction, multiplication, equation, norm construction, tracing, transposition, scaling, juxtaposition, and construction of null and identity matrices. The analysis routines provide for the following

  1. Heart rate regulation during cycle-ergometer exercise via bio-feedback.

    Science.gov (United States)

    Argha, Ahmadreza; Su, Steven W; Hung Nguyen; Celler, Branko G

    2015-08-01

    This paper explains our developed control system which regulates the heart rate (HR) to track a desired trajectory. The controller is indeed a non-conventional non-model-based proportional, integral and derivative (PID) controller. The controller commands are interpreted as biofeedback auditory commands. These commands can be heard and implemented by the exercising subject as a part of the control-loop. However, transmitting a feedback signal while the pedals are not in the appropriate position to efficiently exert force may lead to a cognitive disengagement of the user from the feedback controller. This note explains a novel form of control system regarding as "actuator-based event-driven control system", designed specifically for the purpose of this project. We conclude that the developed event-driven controller makes it possible to precisely regulate HR to a predetermined HR profile.

  2. Semiglobal H-infinity State Feedback Control

    DEFF Research Database (Denmark)

    Cromme, Marc; Stoustrup, Jakob

    1996-01-01

    Semi-global set-stabilizing H-infinity controlis a local within some given compact set such that all statetrajectories are bounded inside the set, and are approaching an openloop invariant subset as time approaches infinity. Sufficientconditions for the existence of a continuous state feedback law...

  3. To Stabilize Power Systems from Various Kind of Oscillations using a State Feedback Controller

    International Nuclear Information System (INIS)

    Afridi, M. A.

    2012-01-01

    Damping of electromechanical oscillations in power systems is one of the major concerns in the operation of power system since many years. These oscillations cause improper of the power system incorporating losses. This thesis work presents the coordinated AVR+PSS structure, called the Desensitized four loops Regulator, designed to damp these oscillations in the power system. It is shown here that it is possible to transform the structure of this controller into any standard IEEE AVR+PSS structure. The AVR+PSS structure obtained through this structure is efficient to damp out many types of oscillations present in the Power system. These models are to be incorporated with the generator models to get a power system model with state feedback control. On simulating the system in Simulink with the controllers we have obtained the power system model with state feedback control and observed that how these controllers are helpful in damping the oscillations. (author)

  4. The Theoretical and Methodological Bases to Form the Parity of State Regulation of the National Economy and Market Self-Regulation

    Directory of Open Access Journals (Sweden)

    Yahno Tetiana P.

    2017-09-01

    Full Text Available The aim of the article is to summarize the existing approaches regarding the optimal balance of mechanisms of economic regulation and identify factors that influence the formation of the parity of state regulation and market self-regulation of economy. The analysis of the existing studies has made it possible to establish that the mixed economy model, which is organized on the basis of the market price system but uses various forms of government intervention to correct macroeconomic instability, is the most optimal one for effective development. The smoothing, preventing of negative consequences of effects of market regulators is the goal of state regulation of economy. It is substantiated that the optimal correlation of mechanisms of state regulation and market self-regulation is not a constant value. The maximum effective ratio in application of these mechanisms will not always be achieved under condition of equal government intervention and self-regulation. It depends on the country’s potential, its involvement in the system of the world market economy, level of development of the society, as well as historical features of the country’s development and phase of the economic cycle. Prospects for further research are the substantiation of a new paradigm for the formation of the parity of state regulation and market self-regulation in the context of financial uncertainty and effect of supranational regulators, growing contradictions of globalization-regionalization based on the use of the system and synergetic approach.

  5. Optimal Regulation of Lumpy Investments

    NARCIS (Netherlands)

    Zwart, G.; Broer, D.P.

    2012-01-01

    When a monopolist has discretion over the timing of infrastructure investments, regulation of post-investment prices interferes with incentivizing socially optimal investment timing. In a model of regulated lumpy investment under uncertainty, we study regulation when the regulator can condition

  6. Global control of reaction wheel pendulum through energy regulation and extended linearization of the state variables

    Directory of Open Access Journals (Sweden)

    Oscar D. Montoya-Giraldo

    2014-01-01

    Full Text Available This paper presents the design and simulation of a global controller for the Reaction Wheel Pendulum system using energy regulation and extended linearization methods for the state feedback. The proposed energy regulation is based on the gradual reduction of the energy of the system to reach the unstable equilibrium point. The signal input for this task is obtained from the Lyapunov stability theory. The extended state feedback controller design is used to get a smooth nonlinear function that extends the region of operation to a bigger range, in contrast with the static linear state feedback obtained through the method of approximate linearization around an operating point. The general designed controller operates with a switching between the two control signals depending upon the region of operation; perturbations are applied in the control signal and the (simulated measured variables to verify the robustness and efficiency of the controller. Finally, simulations and tests using the model of the reaction wheel pendulum system, allow to observe the versatility and functionality of the proposed controller in the entire operation region of the pendulum.

  7. Uncertainty of feedback and state estimation determines the speed of motor adaptation

    Directory of Open Access Journals (Sweden)

    Kunlin Wei

    2010-05-01

    Full Text Available Humans can adapt their motor behaviors to deal with ongoing changes. To achieve this, the nervous system needs to estimate central variables for our movement based on past knowledge and new feedback, both of which are uncertain. In the Bayesian framework, rates of adaptation characterize how noisy feedback is in comparison to the uncertainty of the state estimate. The predictions of Bayesian models are intuitive: the nervous system should adapt slower when sensory feedback is more noisy and faster when its state estimate is more uncertain. Here we want to quantitatively understand how uncertainty in these two factors affects motor adaptation. In a hand reaching experiment we measured trial-by-trial adaptation to a randomly changing visual perturbation to characterize the way the nervous system handles uncertainty in state estimation and feedback. We found both qualitative predictions of Bayesian models confirmed. Our study provides evidence that the nervous system represents and uses uncertainty in state estimate and feedback during motor adaptation.

  8. Prolactin and Male Fertility: The Long and Short Feedback Regulation

    Directory of Open Access Journals (Sweden)

    M. K. Gill-Sharma

    2009-01-01

    Full Text Available In the last 20 years, a pituitary-hypothalamus tissue culture system with intact neural and portal connections has been developed in our lab and used to understand the feedback mechanisms that regulate the secretions of adenohypophyseal hormones and fertility of male rats. In the last decade, several in vivo rat models have also been developed in our lab with a view to substantiate the in vitro findings, in order to delineate the role of pituitary hormones in the regulation of fertility of male rats. These studies have relied on both surgical and pharmacological interventions to modulate the secretions of gonadotropins and testosterone. The interrelationship between the circadian release of reproductive hormones has also been ascertained in normal men. Our studies suggest that testosterone regulates the secretion of prolactin through a long feedback mechanism, which appears to have been conserved from rats to humans. These studies have filled in a major lacuna pertaining to the role of prolactin in male reproductive physiology by demonstrating the interdependence between testosterone and prolactin. Systemic levels of prolactin play a deterministic role in the mechanism of chromatin condensation during spermiogenesis.

  9. Quantum feedback for rapid state preparation in the presence of control imperfections

    International Nuclear Information System (INIS)

    Combes, Joshua; Wiseman, Howard M

    2011-01-01

    Quantum feedback control protocols can improve the operation of quantum devices. Here we examine the performance of a purification protocol when there are imperfections in the controls. The ideal feedback protocol produces an x-eigenstate from a mixed state in the minimum time, and is known as rapid state preparation. The imperfections we examine include time delays in the feedback loop, finite strength feedback, calibration errors and inefficient detection. We analyse these imperfections using the Wiseman-Milburn feedback master equation and related formalism. We find that the protocol is most sensitive to time delays in the feedback loop. For systems with slow dynamics, however, our analysis suggests that inefficient detection would be the bigger problem. We also show how system imperfections, such as dephasing and damping, can be included in a model via the feedback master equation.

  10. Sub-optimal control of fuzzy linear dynamical systems under granular differentiability concept.

    Science.gov (United States)

    Mazandarani, Mehran; Pariz, Naser

    2018-05-01

    This paper deals with sub-optimal control of a fuzzy linear dynamical system. The aim is to keep the state variables of the fuzzy linear dynamical system close to zero in an optimal manner. In the fuzzy dynamical system, the fuzzy derivative is considered as the granular derivative; and all the coefficients and initial conditions can be uncertain. The criterion for assessing the optimality is regarded as a granular integral whose integrand is a quadratic function of the state variables and control inputs. Using the relative-distance-measure (RDM) fuzzy interval arithmetic and calculus of variations, the optimal control law is presented as the fuzzy state variables feedback. Since the optimal feedback gains are obtained as fuzzy functions, they need to be defuzzified. This will result in the sub-optimal control law. This paper also sheds light on the restrictions imposed by the approaches which are based on fuzzy standard interval arithmetic (FSIA), and use strongly generalized Hukuhara and generalized Hukuhara differentiability concepts for obtaining the optimal control law. The granular eigenvalues notion is also defined. Using an RLC circuit mathematical model, it is shown that, due to their unnatural behavior in the modeling phenomenon, the FSIA-based approaches may obtain some eigenvalues sets that might be different from the inherent eigenvalues set of the fuzzy dynamical system. This is, however, not the case with the approach proposed in this study. The notions of granular controllability and granular stabilizability of the fuzzy linear dynamical system are also presented in this paper. Moreover, a sub-optimal control for regulating a Boeing 747 in longitudinal direction with uncertain initial conditions and parameters is gained. In addition, an uncertain suspension system of one of the four wheels of a bus is regulated using the sub-optimal control introduced in this paper. Copyright © 2018 ISA. Published by Elsevier Ltd. All rights reserved.

  11. A dynamic-biased dual-loop-feedback CMOS LDO regulator with fast transient response

    International Nuclear Information System (INIS)

    Wang Han; Sun Maomao

    2014-01-01

    This paper presents a low-dropout regulator (LDO) for portable applications with dual-loop feedback and a dynamic bias circuit. The dual-loop feedback structure is adopted to reduce the output voltage spike and the response time of the LDO. The dynamic bias circuit enhances the slew rate at the gate of the power transistor. In addition, an adaptive miller compensation technique is employed, from which a single pole system is realized and over a 59° phase margin is achieved under the full range of the load current. The proposed LDO has been implemented in a 0.6-μm CMOS process. From the experimental results, the regulator can operate with a minimum dropout voltage of 200 mV at a maximum 300 mA load and I Q of 113 μA. The line regulation and load regulation are improved to 0.1 mV/V and 3.4 μV/mA due to the sufficient loop gain provided by the dual feedback loops. Under a full range load current step, the voltage spikes and the recovery time of the proposed LDO is reduced to 97 mV and 0.142 μs respectively. (semiconductor integrated circuits)

  12. Optimal control for wind turbine system via state-space method

    Science.gov (United States)

    Shanoob, Mudhafar L.

    Renewable energy is becoming a fascinating research interest in future energy production because it is green and does not pollute nature. Wind energy is an excellent example of renewable resources that are evolving. Throughout the history of humanity, wind energy has been used. In ancient time, it was used to grind seeds, sailing etc. Nowadays, wind energy has been used to generate electrical power. Researchers have done a lot of research about using a wind source to generate electricity. As wind flow is not reliable, there is a challenge to get stable electricity out of this varying wind. This problem leads to the use of different control methods and the optimization of these methods to get a stable and reliable electrical energy. In this research, a wind turbine system is considered to study the transient and the steady-state stability; consisting of the aerodynamic system, drive train and generator. The Doubly Feed Induction Generator (DFIG) type generator is used in this thesis. The wind turbine system is connected to power system network. The grid is an infinite bus bar connected to a short transmission line and transformer. The generator is attached to the grid from the stator side. State-space method is used to model the wind turbine parts. The system is modeled and controlled using MATLAB/Simulation software. First, the current-mode control method (PVdq) with (PI) regulator is operated as a reference to find how the system reacts to an unexpected disturbance on the grid side or turbine side. The controller is operated with three scenarios of disruption: Disturbance-mechanical torque input, Step disturbance in the electrical torque reference and Fault Ride-through. In the simulation results, the time response and the transient stability of the system is a product of the disturbances that take a long time to settle. So, for this reason, Linear Quadratic Regulation (LQR) optimal control is utilized to solve this problem. The LQR method is designed based on

  13. Feedback Control of a Solid-State Qubit Using High-Fidelity Projective Measurement

    NARCIS (Netherlands)

    Riste, D.; Bultink, C.C.; Lehnert, K.W.; DiCarlo, L.

    2012-01-01

    We demonstrate feedback control of a superconducting transmon qubit using discrete, projective measurement and conditional coherent driving. Feedback realizes a fast and deterministic qubit reset to a target state with 2.4% error averaged over input superposition states, and allows concatenating

  14. The electoral feedback effects of welfare reform in mature European welfare states

    DEFF Research Database (Denmark)

    Arndt, Christoph

    2012-01-01

    The electoral hazard of welfare state reforms in mature welfare states has been a widely acknowledged feedback effect in the literature. However, the literature does typically no distinct between party families when it comes to the electoral consequences of welfare state reforms and treats...... electorates as unity. This paper analysis the feedback effects of social policy retrenchment under Third Way social democracy since 1994. The paper argues that Third Way reforms resulted in lasting electoral setback for social democracy since these reforms went against the social policy preferences of social....... The restructuring of mature Western welfare states thus accounts for changing patterns of political behaviour as a consequence of policy feedback....

  15. Comparative study of flare control laws. [optimal control of b-737 aircraft approach and landing

    Science.gov (United States)

    Nadkarni, A. A.; Breedlove, W. J., Jr.

    1979-01-01

    A digital 3-D automatic control law was developed to achieve an optimal transition of a B-737 aircraft between various initial glid slope conditions and the desired final touchdown condition. A discrete, time-invariant, optimal, closed-loop control law presented for a linear regulator problem, was extended to include a system being acted upon by a constant disturbance. Two forms of control laws were derived to solve this problem. One method utilized the feedback of integral states defined appropriately and augmented with the original system equations. The second method formulated the problem as a control variable constraint, and the control variables were augmented with the original system. The control variable constraint control law yielded a better performance compared to feedback control law for the integral states chosen.

  16. A novel network integrating a miRNA-203/SNAI1 feedback loop which regulates epithelial to mesenchymal transition.

    Directory of Open Access Journals (Sweden)

    Michèle Moes

    Full Text Available BACKGROUND: The majority of human cancer deaths are caused by metastasis. The metastatic dissemination is initiated by the breakdown of epithelial cell homeostasis. During this phenomenon, referred to as epithelial to mesenchymal transition (EMT, cells change their genetic and trancriptomic program leading to phenotypic and functional alterations. The challenge of understanding this dynamic process resides in unraveling regulatory networks involving master transcription factors (e.g. SNAI1/2, ZEB1/2 and TWIST1 and microRNAs. Here we investigated microRNAs regulated by SNAI1 and their potential role in the regulatory networks underlying epithelial plasticity. RESULTS: By a large-scale analysis on epithelial plasticity, we highlighted miR-203 and its molecular link with SNAI1 and the miR-200 family, key regulators of epithelial homeostasis. During SNAI1-induced EMT in MCF7 breast cancer cells, miR-203 and miR-200 family members were repressed in a timely correlated manner. Importantly, miR-203 repressed endogenous SNAI1, forming a double negative miR203/SNAI1 feedback loop. We integrated this novel miR203/SNAI1 with the known miR200/ZEB feedback loops to construct an a priori EMT core network. Dynamic simulations revealed stable epithelial and mesenchymal states, and underscored the crucial role of the miR203/SNAI1 feedback loop in state transitions underlying epithelial plasticity. CONCLUSION: By combining computational biology and experimental approaches, we propose a novel EMT core network integrating two fundamental negative feedback loops, miR203/SNAI1 and miR200/ZEB. Altogether our analysis implies that this novel EMT core network could function as a switch controlling epithelial cell plasticity during differentiation and cancer progression.

  17. Dynamics of gene expression with positive feedback to histone modifications at bivalent domains

    Science.gov (United States)

    Huang, Rongsheng; Lei, Jinzhi

    2018-03-01

    Experiments have shown that in embryonic stem cells, the promoters of many lineage-control genes contain “bivalent domains”, within which the nucleosomes possess both active (H3K4me3) and repressive (H3K27me3) marks. Such bivalent modifications play important roles in maintaining pluripotency in embryonic stem cells. Here, to investigate gene expression dynamics when there are regulations in bivalent histone modifications and random partition in cell divisions, we study how positive feedback to histone methylation/demethylation controls the transition dynamics of the histone modification patterns along with cell cycles. We constructed a computational model that includes dynamics of histone marks, three-stage chromatin state transitions, transcription and translation, feedbacks from protein product to enzymes to regulate the addition and removal of histone marks, and the inheritance of nucleosome state between cell cycles. The model reveals how dynamics of both nucleosome state transition and gene expression are dependent on the enzyme activities and feedback regulations. Results show that the combination of stochastic histone modification at each cell division and the deterministic feedback regulation work together to adjust the dynamics of chromatin state transition in stem cell regenerations.

  18. Optimal and Autonomous Control Using Reinforcement Learning: A Survey.

    Science.gov (United States)

    Kiumarsi, Bahare; Vamvoudakis, Kyriakos G; Modares, Hamidreza; Lewis, Frank L

    2018-06-01

    This paper reviews the current state of the art on reinforcement learning (RL)-based feedback control solutions to optimal regulation and tracking of single and multiagent systems. Existing RL solutions to both optimal and control problems, as well as graphical games, will be reviewed. RL methods learn the solution to optimal control and game problems online and using measured data along the system trajectories. We discuss Q-learning and the integral RL algorithm as core algorithms for discrete-time (DT) and continuous-time (CT) systems, respectively. Moreover, we discuss a new direction of off-policy RL for both CT and DT systems. Finally, we review several applications.

  19. Why do bacteria regulate public goods by quorum sensing? - How the shapes of cost and benefit functions determine the form of optimal regulation

    Directory of Open Access Journals (Sweden)

    Silja eHeilmann

    2015-07-01

    Full Text Available Many bacteria secrete compounds, which act as public goods. Such compounds are often under quorum sensing (QS regulation, yet it is not understood exactly when bacteria may gain from having a public good under QS regulation.Here, we show that the optimal public good production rate per cell as a function of population size (the optimal production curve, OPC depend crucially on the cost and benefit functions of the public good and that the OPC will fall into one of two categories: Either it is continuous or it jumps from zero discontinuously at a critical population size.If, e.g., the public good has accelerating returns and linear cost, then the OPC is discontinuous and the best strategy thus to ramp up production sharply at a precise population size.By using the example of public goods with accelerating and diminishing returns (and linear cost we are able to determine how the two different categories of OPSs, can best be matched by production regulated through a QS signal feeding back on its own production. We find that the optimal QS parameters are different for the two categories and specifically that public goods, which provide accelerating returns, call for stronger positive signal feedback.

  20. Optimal census by quorum sensing

    Science.gov (United States)

    Taillefumier, Thibaud

    Bacteria regulate their gene expression in response to changes in local cell density in a process called quorum sensing. To synchronize their gene-expression programs, these bacteria need to glean as much information as possible about local density. Our study is the first to physically model the flow of information in a quorum-sensing microbial community, wherein the internal regulator of the individual's response tracks the external cell density via an endogenously generated shared signal. Combining information theory and Lagrangian optimization, we find that quorum-sensing systems can improve their information capabilities by tuning circuit feedbacks. At the population level, external feedback adjusts the dynamic range of the shared input to individuals' detection channels. At the individual level, internal feedback adjusts the regulator's response time to dynamically balance output noise reduction and signal tracking ability. Our analysis suggests that achieving information benefit via feedback requires dedicated systems to control gene expression noise, such as sRNA-based regulation.

  1. Memory State Feedback RMPC for Multiple Time-Delayed Uncertain Linear Systems with Input Constraints

    Directory of Open Access Journals (Sweden)

    Wei-Wei Qin

    2014-01-01

    Full Text Available This paper focuses on the problem of asymptotic stabilization for a class of discrete-time multiple time-delayed uncertain linear systems with input constraints. Then, based on the predictive control principle of receding horizon optimization, a delayed state dependent quadratic function is considered for incorporating MPC problem formulation. By developing a memory state feedback controller, the information of the delayed plant states can be taken into full consideration. The MPC problem is formulated to minimize the upper bound of infinite horizon cost that satisfies the sufficient conditions. Then, based on the Lyapunov-Krasovskii function, a delay-dependent sufficient condition in terms of linear matrix inequality (LMI can be derived to design a robust MPC algorithm. Finally, the digital simulation results prove availability of the proposed method.

  2. Improved State Feedback H∞ Control for Flexible Air-Breathing Hypersonic Vehicles on LMI Approach

    Directory of Open Access Journals (Sweden)

    Zhang Xue

    2017-01-01

    Full Text Available Focusing on a nonlinear longitudinal dynamical model for Air-breathing Hypersonic Flight Vehicles (AHFV, a linearized model on a nominal trim condition is proposed. To stabilize the flight of an AHFV in the presence of external disturbances and actuator uncertainties, a state feedback H∞ control is designed. With bounds on the uncertainties, a feedback stabilization problem is converted to an optimal control problem and the cost function is minimized by solving a set of linear matrix inequalities. Since uncertainties in the design of AHFV are inevitable, to make a comparison, a general H∞ robust controller is constructed by only considering the disturbances firstly. Then the results are extended by incorporating the actual existing uncertainties as well as the external disturbances in the AHFV system. Numerical simulation shows that the controller, which takes both disturbances and uncertainties into account, can effectively stabilize the AHFV system.

  3. Persistent disturbance rejection via state feedback for networked control systems

    Energy Technology Data Exchange (ETDEWEB)

    Yue Dong [Institute of Information and Control Engineering Technology, Nanjing Normal University, 78 Bancang Street, Nanjing, Jiangsu 210042 (China)], E-mail: medongy@njnu.edu.cn; Lam, James [Department of Mechanical Engineering, University of Hong Kong, Pokfulam Road (Hong Kong); Wang Zidong [Department of Information Systems and Computing, Brunel University, Uxbridge, Middlesex UB8 3PH (United Kingdom)], E-mail: Zidong.Wang@brunel.ac.uk

    2009-04-15

    The problem of persistent disturbance rejection via state feedback for networked control systems is concerned based on the Lyapunov function method. The effect of the network conditions, such as network-induced delay and data dropout, is considered in the modeling of the system. It is assumed that the state and the control signals are individually quantized by quantizers on the sensor side and the controller side. The feedback gain and the quantizer parameters that guarantee the internal stability and the disturbance rejection performance of the closed-loop system are obtained by solving some linear matrix inequalities. To illustrate the effectiveness of the proposed method, a numerical example is provided for the design of the feedback gain and the quantizer parameters.

  4. Persistent disturbance rejection via state feedback for networked control systems

    International Nuclear Information System (INIS)

    Yue Dong; Lam, James; Wang Zidong

    2009-01-01

    The problem of persistent disturbance rejection via state feedback for networked control systems is concerned based on the Lyapunov function method. The effect of the network conditions, such as network-induced delay and data dropout, is considered in the modeling of the system. It is assumed that the state and the control signals are individually quantized by quantizers on the sensor side and the controller side. The feedback gain and the quantizer parameters that guarantee the internal stability and the disturbance rejection performance of the closed-loop system are obtained by solving some linear matrix inequalities. To illustrate the effectiveness of the proposed method, a numerical example is provided for the design of the feedback gain and the quantizer parameters.

  5. Optimizing the Timing of Expert Feedback During Simulation-Based Spaced Practice of Endourologic Skills.

    Science.gov (United States)

    Lee, Jason Young; McDougall, Elspeth M; Lineberry, Matthew; Tekian, Ara

    2016-08-01

    Provision of expert feedback is widely acknowledged to be an essential component of simulation-based training. However, little is known about the most effective and efficient ways to provide feedback to novices. Optimizing the timing of expert feedback may improve outcomes while reducing resource requirements. The main objective of this study was to determine the impact of providing early versus late expert feedback to novice learners engaged in a flexible ureteroscopy (fURS) training curriculum. Senior medical students were recruited to participate in this study. Each student participated in a comprehensive fURS training curriculum that included 3 deliberate, independent practice sessions. Baseline and postcourse fURS skill was assessed for each student using a standardized fURS test task. Each student was randomized to either an early feedback group (EFG) or late feedback group (LFG). The EFG participants were provided expert feedback immediately after the baseline skill test, whereas LFG participants were given feedback before their final deliberate, independent practice session. Eighteen senior medical students completed the study (9 EFG and 9 LFG participants). There were no discernible demographic differences between the groups at baseline. When controlling for pretest performance, early rather than late feedback was associated with both shorter postcourse time to completion of the task (19.2 vs. 21.5 minutes, P feedback when learning a novel skill. Further study is required.

  6. A web-based feedback study on optimization-based training and analysis of human decision making

    Directory of Open Access Journals (Sweden)

    Michael Engelhart

    2017-05-01

    Full Text Available The question “How can humans learn efficiently to make decisions in a complex, dynamic, and uncertain environment” is still a very open question. We investigate what effects arise when feedback is given in a computer-simulated microworld that is controlled by participants. This has a direct impact on training simulators that are already in standard use in many professions, e.g., for flight simulators for pilots, and a potential impact on a better understanding of human decision making in general. Our study is based on a benchmark microworld with an economic framing, the IWR Tailorshop. N=94 participants played four rounds of the microworld, each 10 months, via a web interface. We propose a new approach to quantify performance and learning, which is based on a mathematical model of the microworld and optimization. Six participant groups receive different kinds of feedback in a training phase, then results in a performance phase without feedback are analyzed. As a main result, feedback of optimal solutions in training rounds improved model knowledge, early learning, and performance, especially when this information is encoded in a graphical representation (arrows.

  7. A transient-enhanced NMOS low dropout voltage regulator with parallel feedback compensation

    International Nuclear Information System (INIS)

    Wang Han; Tan Lin

    2016-01-01

    This paper presents a transient-enhanced NMOS low-dropout regulator (LDO) for portable applications with parallel feedback compensation. The parallel feedback structure adds a dynamic zero to get an adequate phase margin with a load current variation from 0 to 1 A. A class-AB error amplifier and a fast charging/discharging unit are adopted to enhance the transient performance. The proposed LDO has been implemented in a 0.35 μm BCD process. From experimental results, the regulator can operate with a minimum dropout voltage of 150 mV at a maximum 1 A load and I Q of 165 μA. Under the full range load current step, the voltage undershoot and overshoot of the proposed LDO are reduced to 38 mV and 27 mV respectively. (paper)

  8. Regulation of Dynamical Systems to Optimal Solutions of Semidefinite Programs: Algorithms and Applications to AC Optimal Power Flow

    Energy Technology Data Exchange (ETDEWEB)

    Dall' Anese, Emiliano; Dhople, Sairaj V.; Giannakis, Georgios B.

    2015-07-01

    This paper considers a collection of networked nonlinear dynamical systems, and addresses the synthesis of feedback controllers that seek optimal operating points corresponding to the solution of pertinent network-wide optimization problems. Particular emphasis is placed on the solution of semidefinite programs (SDPs). The design of the feedback controller is grounded on a dual e-subgradient approach, with the dual iterates utilized to dynamically update the dynamical-system reference signals. Global convergence is guaranteed for diminishing stepsize rules, even when the reference inputs are updated at a faster rate than the dynamical-system settling time. The application of the proposed framework to the control of power-electronic inverters in AC distribution systems is discussed. The objective is to bridge the time-scale separation between real-time inverter control and network-wide optimization. Optimization objectives assume the form of SDP relaxations of prototypical AC optimal power flow problems.

  9. Corruption and optimal regulation under common agency

    Directory of Open Access Journals (Sweden)

    Pedro Hemsley

    2016-05-01

    Full Text Available I show that it is optimal to separate non-benevolent regulators when regulated projects are large. Separation prevents regulators from coordinating to appropriate all of the agent's informational rent when they know the type of the latter; therefore, there is a trade-off between saving on informational rent and efficiency, since the game between the regulators induced by separation causes further distortions when compared to the allocation under one regulator. When the informational rent at stake is large due to the size of the project, separation is the optimal institutional answer.

  10. Switching of the positive feedback for RAS activation by a concerted function of SOS membrane association domains.

    Science.gov (United States)

    Nakamura, Yuki; Hibino, Kayo; Yanagida, Toshio; Sako, Yasushi

    2016-01-01

    Son of sevenless (SOS) is a guanine nucleotide exchange factor that regulates cell behavior by activating the small GTPase RAS. Recent in vitro studies have suggested that an interaction between SOS and the GTP-bound active form of RAS generates a positive feedback loop that propagates RAS activation. However, it remains unclear how the multiple domains of SOS contribute to the regulation of the feedback loop in living cells. Here, we observed single molecules of SOS in living cells to analyze the kinetics and dynamics of SOS behavior. The results indicate that the histone fold and Grb2-binding domains of SOS concertedly produce an intermediate state of SOS on the cell surface. The fraction of the intermediated state was reduced in positive feedback mutants, suggesting that the feedback loop functions during the intermediate state. Translocation of RAF, recognizing the active form of RAS, to the cell surface was almost abolished in the positive feedback mutants. Thus, the concerted functions of multiple membrane-associating domains of SOS governed the positive feedback loop, which is crucial for cell fate decision regulated by RAS.

  11. Skin barrier homeostasis in atopic dermatitis: feedback regulation of kallikrein activity.

    Directory of Open Access Journals (Sweden)

    Reiko J Tanaka

    Full Text Available Atopic dermatitis (AD is a widely spread cutaneous chronic disease characterised by sensitive reactions (eg. eczema to normally innocuous elements. Although relatively little is understood about its underlying mechanisms due to its complexity, skin barrier dysfunction has been recognised as a key factor in the development of AD. Skin barrier homeostasis requires tight control of the activity of proteases, called kallikreins (KLKs, whose activity is regulated by a complex network of protein interactions that remains poorly understood despite its pathological importance. Characteristic symptoms of AD include the outbreak of inflammation triggered by external (eg. mechanical and chemical stimulus and the persistence and aggravation of inflammation even if the initial stimulus disappears. These characteristic symptoms, together with some experimental data, suggest the presence of positive feedback regulation for KLK activity by inflammatory signals. We developed simple mathematical models for the KLK activation system to study the effects of feedback loops and carried out bifurcation analysis to investigate the model behaviours corresponding to inflammation caused by external stimulus. The model analysis confirmed that the hypothesised core model mechanisms capture the essence of inflammation outbreak by a defective skin barrier. Our models predicted the outbreaks of inflammation at weaker stimulus and its longer persistence in AD patients compared to healthy control. We also proposed a novel quantitative indicator for inflammation level by applying principal component analysis to microarray data. The model analysis reproduced qualitative AD characteristics revealed by this indicator. Our results strongly implicate the presence and importance of feedback mechanisms in KLK activity regulation. We further proposed future experiments that may provide informative data to enhance the system-level understanding on the regulatory mechanisms of skin barrier

  12. Optimal resource states for local state discrimination

    Science.gov (United States)

    Bandyopadhyay, Somshubhro; Halder, Saronath; Nathanson, Michael

    2018-02-01

    We study the problem of locally distinguishing pure quantum states using shared entanglement as a resource. For a given set of locally indistinguishable states, we define a resource state to be useful if it can enhance local distinguishability and optimal if it can distinguish the states as well as global measurements and is also minimal with respect to a partial ordering defined by entanglement and dimension. We present examples of useful resources and show that an entangled state need not be useful for distinguishing a given set of states. We obtain optimal resources with explicit local protocols to distinguish multipartite Greenberger-Horne-Zeilinger and graph states and also show that a maximally entangled state is an optimal resource under one-way local operations and classical communication to distinguish any bipartite orthonormal basis which contains at least one entangled state of full Schmidt rank.

  13. An Exploration of the Relationship between Students' Preferences for Formative Feedback and Self-Regulated Learning Skills

    Science.gov (United States)

    Çakir, Recep; Korkmaz, Özgen; Bacanak, Ahmet; Arslan, Ömer

    2016-01-01

    The purpose of this study is to explore students' preferences for formative feedback and its relationship with their self-regulated learning skills. The study used a mixed methods approach in which quantitative data collection and analysis was followed by qualitative data collection and analysis. "Preferences toward Formative Feedback"…

  14. Improving Convergence of Iterative Feedback Tuning using Optimal External Perturbations

    DEFF Research Database (Denmark)

    Huusom, Jakob Kjøbsted; Hjalmarsson, Håkon; Poulsen, Niels Kjølstad

    2008-01-01

    Iterative feedback tuning constitutes an attractive control loop tuning method for processes in the absence of sufficient process insight. It is a purely data driven approach to optimization of the loop performance. The standard formulation ensures an unbiased estimate of the loop performance cost...... function gradient, which is used in a search algorithm. A slow rate of convergence of the tuning method is often experienced when tuning for disturbance rejection. This is due to a poor signal to noise ratio in the process data. A method is proposed for increasing the information content in data...

  15. Effects of feedback reliability on feedback-related brain activity: A feedback valuation account.

    Science.gov (United States)

    Ernst, Benjamin; Steinhauser, Marco

    2018-04-06

    Adaptive decision making relies on learning from feedback. Because feedback sometimes can be misleading, optimal learning requires that knowledge about the feedback's reliability be utilized to adjust feedback processing. Although previous research has shown that feedback reliability indeed influences feedback processing, the underlying mechanisms through which this is accomplished remain unclear. Here we propose that feedback processing is adjusted by the adaptive, top-down valuation of feedback. We assume that unreliable feedback is devalued relative to reliable feedback, thus reducing the reward prediction errors that underlie feedback-related brain activity and learning. A crucial prediction of this account is that the effects of feedback reliability are susceptible to contrast effects. That is, the effects of feedback reliability should be enhanced when both reliable and unreliable feedback are experienced within the same context, as compared to when only one level of feedback reliability is experienced. To evaluate this prediction, we measured the event-related potentials elicited by feedback in two experiments in which feedback reliability was varied either within or between blocks. We found that the fronto-central valence effect, a correlate of reward prediction errors during reinforcement learning, was reduced for unreliable feedback. But this result was obtained only when feedback reliability was varied within blocks, thus indicating a contrast effect. This suggests that the adaptive valuation of feedback is one mechanism underlying the effects of feedback reliability on feedback processing.

  16. A switched state feedback law for the stabilization of LTI systems.

    Energy Technology Data Exchange (ETDEWEB)

    Santarelli, Keith R.

    2009-09-01

    Inspired by prior work in the design of switched feedback controllers for second order systems, we develop a switched state feedback control law for the stabilization of LTI systems of arbitrary dimension. The control law operates by switching between two static gain vectors in such a way that the state trajectory is driven onto a stable n - 1 dimensional hyperplane (where n represents the system dimension). We begin by briefly examining relevant geometric properties of the phase portraits in the case of two-dimensional systems to develop intuition, and we then show how these geometric properties can be expressed as algebraic constraints on the switched vector fields that are applicable to LTI systems of arbitrary dimension. We then derive necessary and sufficient conditions to ensure stabilizability of the resulting switched system (characterized primarily by simple conditions on eigenvalues), and describe an explicit procedure for designing stabilizing controllers. We then show how the newly developed control law can be applied to the problem of minimizing the maximal Lyapunov exponent of the corresponding closed-loop state trajectories, and we illustrate the closed-loop transient performance of these switched state feedback controllers via multiple examples.

  17. Linear systems optimal and robust control

    CERN Document Server

    Sinha, Alok

    2007-01-01

    Introduction Overview Contents of the Book State Space Description of a Linear System Transfer Function of a Single Input/Single Output (SISO) System State Space Realizations of a SISO System SISO Transfer Function from a State Space Realization Solution of State Space Equations Observability and Controllability of a SISO System Some Important Similarity Transformations Simultaneous Controllability and Observability Multiinput/Multioutput (MIMO) Systems State Space Realizations of a Transfer Function Matrix Controllability and Observability of a MIMO System Matrix-Fraction Description (MFD) MFD of a Transfer Function Matrix for the Minimal Order of a State Space Realization Controller Form Realization from a Right MFD Poles and Zeros of a MIMO Transfer Function Matrix Stability Analysis State Feedback Control and Optimization State Variable Feedback for a Single Input System Computation of State Feedback Gain Matrix for a Multiinput System State Feedback Gain Matrix for a Multi...

  18. ℋ∞ constant gain state feedback stabilization of stochastic hybrid systems with Wiener process

    Directory of Open Access Journals (Sweden)

    E. K. Boukas

    2004-01-01

    Full Text Available This paper considers the stabilization problem of the class of continuous-time linear stochastic hybrid systems with Wiener process. The ℋ∞ state feedback stabilization problem is treated. A state feedback controller with constant gain that does not require access to the system mode is designed. LMI-based conditions are developed to design the state feedback controller with constant gain that stochastically stabilizes the studied class of systems and, at the same time, achieve the disturbance rejection of a desired level. The minimum disturbance rejection is also determined. Numerical examples are given to show the usefulness of the proposed results.

  19. ETSON proposal on the European operational experience feedback system

    International Nuclear Information System (INIS)

    Maqua, Michael; Bertrand, Remy; Gelder, Pieter de

    2007-01-01

    The new IAEA Safety Fundamentals states regarding the operating experience feedback: The feedback of operating experience from facilities and activities - and, where relevant, from elsewhere - is a key means of enhancing safety. Processes must be put in place for the feedback and analysis of operating experience, including initiating events, accident precursors, near misses, accidents and unauthorized acts, so that lessons may be learned, shared and acted upon. This presentation deals with the proposal of the ETSON (European TSO Network) to optimize the European operating experiences feedback (OEF). It is generally recognized that the efficiency of nuclear safety supervision by public authorities is based on two key requirements: - the existence of a competent authority at national level, benefiting from an appropriate legislative and regulatory basis, from adequate (quantitatively and qualitatively) human resources, particularly for inspection purposes, - the availability of resources devoted to highly specialised independent technical expertise, in order to provide competent authorities with pertinent technical opinions on: -- the safety files provided by operators, for the purpose of licensing corresponding activities, -- the exploitation for regulatory purposes of the operating experience feed back from licensed nuclear installations. There are two worldwide systems intended to learn lessons from experience: the WANO (World Association of Nuclear Operators) system established by the licensees with access restricted to operating organizations and the IRS system jointly operated by IAEA and OECD/NEA accessible to regulators and to some other users nominated by the regulators in their countries. The IRS itself is dedicated to the analysis of safety significant operating events. NEA/CNRA runs a permanent working group on operating experience (WGOE). WGOE provides among other things also generic reports on safety concerns related to operating experiences and

  20. Optimally cloned binary coherent states

    Science.gov (United States)

    Müller, C. R.; Leuchs, G.; Marquardt, Ch.; Andersen, U. L.

    2017-10-01

    Binary coherent state alphabets can be represented in a two-dimensional Hilbert space. We capitalize this formal connection between the otherwise distinct domains of qubits and continuous variable states to map binary phase-shift keyed coherent states onto the Bloch sphere and to derive their quantum-optimal clones. We analyze the Wigner function and the cumulants of the clones, and we conclude that optimal cloning of binary coherent states requires a nonlinearity above second order. We propose several practical and near-optimal cloning schemes and compare their cloning fidelity to the optimal cloner.

  1. Optimal control of coupled parabolic-hyperbolic non-autonomous PDEs: infinite-dimensional state-space approach

    Science.gov (United States)

    Aksikas, I.; Moghadam, A. Alizadeh; Forbes, J. F.

    2018-04-01

    This paper deals with the design of an optimal state-feedback linear-quadratic (LQ) controller for a system of coupled parabolic-hypebolic non-autonomous partial differential equations (PDEs). The infinite-dimensional state space representation and the corresponding operator Riccati differential equation are used to solve the control problem. Dynamical properties of the coupled system of interest are analysed to guarantee the existence and uniqueness of the solution of the LQ-optimal control problem and also to guarantee the exponential stability of the closed-loop system. Thanks to the eigenvalues and eigenfunctions of the parabolic operator and also the fact that the hyperbolic-associated operator Riccati differential equation can be converted to a scalar Riccati PDE, an algorithm to solve the LQ control problem has been presented. The results are applied to a non-isothermal packed-bed catalytic reactor. The LQ optimal controller designed in the early portion of the paper is implemented for the original non-linear model. Numerical simulations are performed to show the controller performances.

  2. A reduced feedback proportional fair multiuser scheduling scheme

    KAUST Repository

    Shaqfeh, Mohammad

    2011-12-01

    Multiuser switched-diversity scheduling schemes were recently proposed in order to overcome the heavy feedback requirements of conventional opportunistic scheduling schemes by applying a threshold-based, distributed and ordered scheduling mechanism. A slight reduction in the prospected multiuser diversity gains is an acceptable trade-off for great savings in terms of required channel-state-information feedback messages. In this work, we propose a novel proportional fair multiuser switched-diversity scheduling scheme and we demonstrate that it can be optimized using a practical and distributed method to obtain the per-user feedback thresholds. We demonstrate by numerical examples that our reduced feedback proportional fair scheduler operates within 0.3 bits/sec/Hz from the achievable rates by the conventional full feedback proportional fair scheduler in Rayleigh fading conditions. © 2011 IEEE.

  3. Negative feedback regulation of Homer 1a on norepinephrine-dependent cardiac hypertrophy

    Energy Technology Data Exchange (ETDEWEB)

    Chiarello, Carmelina; Bortoloso, Elena; Carpi, Andrea; Furlan, Sandra; Volpe, Pompeo, E-mail: pompeo.volpe@unipd.it

    2013-07-15

    Homers are scaffolding proteins that modulate diverse cell functions being able to assemble signalling complexes. In this study, the presence, sub-cellular distribution and function of Homer 1 was investigated. Homer 1a and Homer 1b/c are constitutively expressed in cardiac muscle of both mouse and rat and in HL-1 cells, a cardiac cell line. As judged by confocal immunofluorescence microscopy, Homer 1a displays sarcomeric and peri-nuclear localization. In cardiomyocytes and cultured HL-1 cells, the hypertrophic agonist norepinephrine (NE) induces α{sub 1}-adrenergic specific Homer 1a over-expression, with a two-to-three-fold increase within 1 h, and no up-regulation of Homer 1b/c, as judged by Western blot and qPCR. In HL-1 cells, plasmid-driven over-expression of Homer 1a partially antagonizes activation of ERK phosphorylation and ANF up-regulation, two well-established, early markers of hypertrophy. At the morphometric level, NE-induced increase of cell size is likewise and partially counteracted by exogenous Homer 1a. Under the same experimental conditions, Homer 1b/c does not have any effect on ANF up-regulation nor on cell hypertrophy. Thus, Homer 1a up-regulation is associated to early stages of cardiac hypertrophy and appears to play a negative feedback regulation on molecular transducers of hypertrophy. -- Highlights: • Homer 1a is constitutively expressed in cardiac tissue. • In HL-1 cells, norepinephrine activates signaling pathways leading to hypertrophy. • Homer 1a up-regulation is an early event of norepinephrine-induced hypertrophy. • Homer 1a plays a negative feedback regulation modulating pathological hypertrophy. • Over-expression of Homer 1a per se does not induce hypertrophy.

  4. Negative feedback regulation of Homer 1a on norepinephrine-dependent cardiac hypertrophy

    International Nuclear Information System (INIS)

    Chiarello, Carmelina; Bortoloso, Elena; Carpi, Andrea; Furlan, Sandra; Volpe, Pompeo

    2013-01-01

    Homers are scaffolding proteins that modulate diverse cell functions being able to assemble signalling complexes. In this study, the presence, sub-cellular distribution and function of Homer 1 was investigated. Homer 1a and Homer 1b/c are constitutively expressed in cardiac muscle of both mouse and rat and in HL-1 cells, a cardiac cell line. As judged by confocal immunofluorescence microscopy, Homer 1a displays sarcomeric and peri-nuclear localization. In cardiomyocytes and cultured HL-1 cells, the hypertrophic agonist norepinephrine (NE) induces α 1 -adrenergic specific Homer 1a over-expression, with a two-to-three-fold increase within 1 h, and no up-regulation of Homer 1b/c, as judged by Western blot and qPCR. In HL-1 cells, plasmid-driven over-expression of Homer 1a partially antagonizes activation of ERK phosphorylation and ANF up-regulation, two well-established, early markers of hypertrophy. At the morphometric level, NE-induced increase of cell size is likewise and partially counteracted by exogenous Homer 1a. Under the same experimental conditions, Homer 1b/c does not have any effect on ANF up-regulation nor on cell hypertrophy. Thus, Homer 1a up-regulation is associated to early stages of cardiac hypertrophy and appears to play a negative feedback regulation on molecular transducers of hypertrophy. -- Highlights: • Homer 1a is constitutively expressed in cardiac tissue. • In HL-1 cells, norepinephrine activates signaling pathways leading to hypertrophy. • Homer 1a up-regulation is an early event of norepinephrine-induced hypertrophy. • Homer 1a plays a negative feedback regulation modulating pathological hypertrophy. • Over-expression of Homer 1a per se does not induce hypertrophy

  5. The pointer basis and the feedback stabilization of quantum systems

    International Nuclear Information System (INIS)

    Li, L; Chia, A; Wiseman, H M

    2014-01-01

    The dynamics for an open quantum system can be ‘unravelled’ in infinitely many ways, depending on how the environment is monitored, yielding different sorts of conditioned states, evolving stochastically. In the case of ideal monitoring these states are pure, and the set of states for a given monitoring forms a basis (which is overcomplete in general) for the system. It has been argued elsewhere (Atkins et al 2005 Europhys. Lett. 69 163) that the ‘pointer basis’ as introduced by Zurek et al (1993 Phys. Rev. Lett. 70 1187), should be identified with the unravelling-induced basis which decoheres most slowly. Here we show the applicability of this concept of pointer basis to the problem of state stabilization for quantum systems. In particular we prove that for linear Gaussian quantum systems, if the feedback control is assumed to be strong compared to the decoherence of the pointer basis, then the system can be stabilized in one of the pointer basis states with a fidelity close to one (the infidelity varies inversely with the control strength). Moreover, if the aim of the feedback is to maximize the fidelity of the unconditioned system state with a pure state that is one of its conditioned states, then the optimal unravelling for stabilizing the system in this way is that which induces the pointer basis for the conditioned states. We illustrate these results with a model system: quantum Brownian motion. We show that even if the feedback control strength is comparable to the decoherence, the optimal unravelling still induces a basis very close to the pointer basis. However if the feedback control is weak compared to the decoherence, this is not the case. (paper)

  6. Feedback controlled dephasing and population relaxation in a two-level system

    International Nuclear Information System (INIS)

    Wang Jin

    2009-01-01

    This Letter presents the maximum achievable stability and purity that can be obtained in a two-level system with both dephasing and population relaxation processes by using homodyne-mediated feedback control. An analytic formula giving the optimal amplitudes of the driving and feedback for the steady-state is also presented. Experimental examples are used to show the importance of controlling the dephasing process.

  7. A biomolecular proportional integral controller based on feedback regulations of protein level and activity.

    Science.gov (United States)

    Mairet, Francis

    2018-02-01

    Homeostasis is the capacity of living organisms to keep internal conditions regulated at a constant level, despite environmental fluctuations. Integral feedback control is known to play a key role in this behaviour. Here, I show that a feedback system involving transcriptional and post-translational regulations of the same executor protein acts as a proportional integral (PI) controller, leading to enhanced transient performances in comparison with a classical integral loop. Such a biomolecular controller-which I call a level and activity-PI controller (LA-PI)-is involved in the regulation of ammonium uptake by Escherichia coli through the transporter AmtB. The P II molecules, which reflect the nitrogen status of the cell, inhibit both the production of AmtB and its activity (via the NtrB-NtrC system and the formation of a complex with GlnK, respectively). Other examples of LA-PI controller include copper and zinc transporters, and the redox regulation in photosynthesis. This scheme has thus emerged through evolution in many biological systems, surely because of the benefits it offers in terms of performances (rapid and perfect adaptation) and economy (protein production according to needs).

  8. Occupant feedback based model predictive control for thermal comfort and energy optimization: A chamber experimental evaluation

    International Nuclear Information System (INIS)

    Chen, Xiao; Wang, Qian; Srebric, Jelena

    2016-01-01

    Highlights: • This study evaluates an occupant-feedback driven Model Predictive Controller (MPC). • The MPC adjusts indoor temperature based on a dynamic thermal sensation (DTS) model. • A chamber model for predicting chamber air temperature is developed and validated. • Experiments show that MPC using DTS performs better than using Predicted Mean Vote. - Abstract: In current centralized building climate control, occupants do not have much opportunity to intervene the automated control system. This study explores the benefit of using thermal comfort feedback from occupants in the model predictive control (MPC) design based on a novel dynamic thermal sensation (DTS) model. This DTS model based MPC was evaluated in chamber experiments. A hierarchical structure for thermal control was adopted in the chamber experiments. At the high level, an MPC controller calculates the optimal supply air temperature of the chamber heating, ventilation, and air conditioning (HVAC) system, using the feedback of occupants’ votes on thermal sensation. At the low level, the actual supply air temperature is controlled by the chiller/heater using a PI control to achieve the optimal set point. This DTS-based MPC was also compared to an MPC designed based on the Predicted Mean Vote (PMV) model for thermal sensation. The experiment results demonstrated that the DTS-based MPC using occupant feedback allows significant energy saving while maintaining occupant thermal comfort compared to the PMV-based MPC.

  9. Optimal Regulation of Virtual Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Dall Anese, Emiliano; Guggilam, Swaroop S.; Simonetto, Andrea; Chen, Yu Christine; Dhople, Sairaj V.

    2018-03-01

    This paper develops a real-time algorithmic framework for aggregations of distributed energy resources (DERs) in distribution networks to provide regulation services in response to transmission-level requests. Leveraging online primal-dual-type methods for time-varying optimization problems and suitable linearizations of the nonlinear AC power-flow equations, we believe this work establishes the system-theoretic foundation to realize the vision of distribution-level virtual power plants. The optimization framework controls the output powers of dispatchable DERs such that, in aggregate, they respond to automatic-generation-control and/or regulation-services commands. This is achieved while concurrently regulating voltages within the feeder and maximizing customers' and utility's performance objectives. Convergence and tracking capabilities are analytically established under suitable modeling assumptions. Simulations are provided to validate the proposed approach.

  10. Effect of biased feedback on motor imagery learning in BCI-teleoperation system

    Directory of Open Access Journals (Sweden)

    Maryam eAlimardani

    2014-04-01

    Full Text Available Feedback design is an important issue in motor imagery BCI systems. Regardless, to date it has not been reported how feedback presentation can optimize co-adaptation between a human brain and such systems. This paper assesses the effect of realistic visual feedback on users’ BC performance and motor imagery skills. We previously developed a tele-operation system for a pair of humanlike robotic hands and showed that BCI control of such hands along with first-person perspective visual feedback of movements can arouse a sense of embodiment in the operators. In the first stage of this study, we found that the intensity of this ownership illusion was associated with feedback presentation and subjects’ performance during BCI motion control. In the second stage, we probed the effect of positive and negative feedback bias on subjects’ BCI performance and motor imagery skills. Although the subject specific classifier, which was set up at the beginning of experiment, detected no significant change in the subjects’ online performance, evaluation of brain activity patterns revealed that subjects’ self-regulation of motor imagery features improved due to a positive bias of feedback and a possible occurrence of ownership illusion. Our findings suggest that in general training protocols for BCIs, manipulation of feedback can play an important role in the optimization of subjects’ motor imagery skills.

  11. Feedback loops and reciprocal regulation: recurring motifs in the systems biology of the cell cycle

    OpenAIRE

    Ferrell, James E.

    2013-01-01

    The study of eukaryotic cell cycle regulation over the last several decades has led to a remarkably detailed understanding of the complex regulatory system that drives this fundamental process. This allows us to now look for recurring motifs in the regulatory system. Among these are negative feedback loops, which underpin checkpoints and generate cell cycle oscillations; positive feedback loops, which promote oscillations and make cell cycle transitions switch-like and unidirectional; and rec...

  12. MR-guided HIFU treatment of symptomatic uterine fibroids using novel feedback-regulated volumetric ablation: effectiveness and clinical practice.

    Science.gov (United States)

    Ruhnke, H; Eckey, T; Bohlmann, M K; Beldoch, M P; Neumann, A; Agic, A; Hägele, J; Diedrich, K; Barkhausen, J; Hunold, P

    2013-09-01

    To evaluate a novel feedback-regulated volumetric sonication method in MR-guided HIFU treatment of symptomatic uterine fibroids. 27 fibroids with an average volume of 124.9 ± 139.8 cc in 18 women with symptomatic uterine fibroids were ablated using the new HIFU system Sonalleve (1.5 T MR system Achieva, Philips). 21 myomas in 13 women were reevaluated 6 months later. Standard (treatment) cells (TC) and feedback-regulated (feedback) cells (FC) with a diameter of 4, 8, 12, and 16 mm were used and compared concerning sonication success, diameter of induced necrosis, and maximum achieved temperature. The non-perfused volume ratio (NPV related to myoma volume) was quantified. The fibroid volume was measured before, 1 month, and 6 months after therapy. Symptoms were quantified using a specific questionnaire (UFS-QoL). In total, 205 TC and 227 FC were applied. The NPV ratio was 23 ± 15 % (2 - 55). The TC were slightly smaller than intended (-3.9 ± 52 %; range, -100 - 81), while the FC were 20.1 ± 25.3 % bigger (p = 0.02). Feedback mechanism is less diversifying in diameter (p feedback cells leads to more contiguous necrosis in diameter and a less diversifying temperature. ▶ MR-guided HIFU ablation of symptomatic uterine fibroids is a valuable treatment option. ▶ By non-invasive HIFU fibroid volumes can be reduced and symptoms improved. ▶ The novel feedback-regulated treatment cells offer advantages over standard treatment cells. © Georg Thieme Verlag KG Stuttgart · New York.

  13. Application of Physiological Self-Regulation and Adaptive Task Allocation Techniques for Controlling Operator Hazardous States of Awareness

    Science.gov (United States)

    Prinzel, Lawrence J., III; Pope, Alan T.; Freeman, Frederick G.

    2001-01-01

    Prinzel, Hadley, Freeman, and Mikulka found that adaptive task allocation significantly enhanced performance only when used at the endpoints of the task workload continuum (i.e., very low or high workload), but that the technique degraded performance if invoked during other levels of task demand. These researchers suggested that other techniques should be used in conjunction with adaptive automation to help minimize the onset of hazardous states of awareness (HSA) and keep the operator 'in-the-loop.' The paper reports on such a technique that uses psychophysiological self-regulation to modulate the level of task engagement. Eighteen participants were assigned to three groups (self-regulation, false feedback, and control) and performed a compensatory tracking task that was cycled between three levels of task difficulty on the basis of the electroencephalogram (EEG) record. Those participants who had received self-regulation training performed significantly better and reported lower NASA-TLX scores than participants in the false feedback and control groups. Furthermore, the false feedback and control groups had significantly more task allocations resulting in return-to-manual performance decrements and higher EEG difference scores. Theoretical and practical implications of these results for adaptive automation are discussed.

  14. Multi-model MPC with output feedback

    Directory of Open Access Journals (Sweden)

    J. M. Perez

    2014-03-01

    Full Text Available In this work, a new formulation is presented for the model predictive control (MPC of a process system that is represented by a finite set of models, each one corresponding to a different operating point. The general case is considered of systems with stable and integrating outputs in closed-loop with output feedback. For this purpose, the controller is based on a non-minimal order model where the state is built with the measured outputs and the manipulated inputs of the control system. Therefore, the state can be considered as perfectly known and, consequently, there is no need to include a state observer in the control loop. This property of the proposed modeling approach is convenient to extend previous stability results of the closed loop system with robust MPC controllers based on state feedback. The controller proposed here is based on the solution of two optimization problems that are solved sequentially at the same time step. The method is illustrated with a simulated example of the process industry. The rigorous simulation of the control of an adiabatic flash of a multi-component hydrocarbon mixture illustrates the application of the robust controller. The dynamic simulation of this process is performed using EMSO - Environment Model Simulation and Optimization. Finally, a comparison with a linear MPC using a single model is presented.

  15. Feed-Back Regulation of Haemopoiesis

    Energy Technology Data Exchange (ETDEWEB)

    Feldman, M. [Department of Cell Biology, Weizmann Institute of Science, Rehovoth (Israel)

    1968-08-15

    Studies ate reported on the feed-back regulation of erythropoiesis by means of the intrasplenic cloning system of haemopoietic cells. Polycythaemia, produced by passive transfusion of synzeneic, allogeneic or xenogeneic red blood cells, inhibited the formation of bone-marrow derived erythroid clones. Polycythaemia also inhibited the formation of erythroid clones of endogenous stem cells. Oxygen overloading was found to be a necessary factor in the suppression of erythroid clone formation: no suppression of erythroid colonies was observed when polycythaemic animals were kept under hypoxic conditions. Erythropoietin, either of exogenous or of endogenous origin, elicited a reformation of erythroid clones in 'suppressed' animals. Studies on the kinetics of reformation of erythroid clones after the administration of erythropoietin suggested that the colony-forming stem cell can replicate a few times in the absence of erythropoietin and the cell progeny thus formed are the target cells for erythropoietin action. If, indeed, the colony-forming cell replicates in the absence of the specific inducer, then the cells thus formed should themselves be stem cells. This was substantiated by demonstrating that the cloning efficiency of spleens of polycythaemic recipients was higher than that of non-polycythaemic animals. Experiments indicating that erythroid clones produced by erythropoietin in polycythaemic animals disappeared after the discontinuance of erythropoietin application demonstrated the distinction between the 'mitogenic' and the 'morphogenetic' effects of erythropoietin. The latter seemed to be operated by an early transcription of RNA for proteins necessary for the complete maturation of the red blood cell, Erythroid clones produced by foetal haemopoietic stem cells seemed to be regulated by a different mechanism from that which controls the formation of bone-marrow derived clones. Clones produced by foetal cells were only partially suppressed in the polycythaemic

  16. Incremental passivity and output regulation for switched nonlinear systems

    Science.gov (United States)

    Pang, Hongbo; Zhao, Jun

    2017-10-01

    This paper studies incremental passivity and global output regulation for switched nonlinear systems, whose subsystems are not required to be incrementally passive. A concept of incremental passivity for switched systems is put forward. First, a switched system is rendered incrementally passive by the design of a state-dependent switching law. Second, the feedback incremental passification is achieved by the design of a state-dependent switching law and a set of state feedback controllers. Finally, we show that once the incremental passivity for switched nonlinear systems is assured, the output regulation problem is solved by the design of global nonlinear regulator controllers comprising two components: the steady-state control and the linear output feedback stabilising controllers, even though the problem for none of subsystems is solvable. Two examples are presented to illustrate the effectiveness of the proposed approach.

  17. Feedback control of nonlinear quantum systems: a rule of thumb.

    Science.gov (United States)

    Jacobs, Kurt; Lund, Austin P

    2007-07-13

    We show that in the regime in which feedback control is most effective - when measurements are relatively efficient, and feedback is relatively strong - then, in the absence of any sharp inhomogeneity in the noise, it is always best to measure in a basis that does not commute with the system density matrix than one that does. That is, it is optimal to make measurements that disturb the state one is attempting to stabilize.

  18. Fuzzy combination of fuzzy and switching state-feedback controllers for nonlinear systems subject to parameter uncertainties.

    Science.gov (United States)

    Lam, H K; Leung, Frank H F

    2005-04-01

    This paper presents a fuzzy controller, which involves a fuzzy combination of local fuzzy and global switching state-feedback controllers, for nonlinear systems subject to parameter uncertainties with known bounds. The nonlinear system is represented by a fuzzy combined Takagi-Sugeno-Kang model, which is a fuzzy combination of the global and local fuzzy plant models. By combining the local fuzzy and global switching state-feedback controllers using fuzzy logic techniques, the advantages of both controllers can be retained and the undesirable chattering effect introduced by the global switching state-feedback controller can be eliminated. The steady-state error introduced by the global switching state-feedback controller when a saturation function is used can also be removed. Stability conditions, which are related to the system matrices of the local and global closed-loop systems, are derived to guarantee the closed-loop system stability. An application example will be given to demonstrate the merits of the proposed approach.

  19. Reexamination of optimal quantum state estimation of pure states

    International Nuclear Information System (INIS)

    Hayashi, A.; Hashimoto, T.; Horibe, M.

    2005-01-01

    A direct derivation is given for the optimal mean fidelity of quantum state estimation of a d-dimensional unknown pure state with its N copies given as input, which was first obtained by Hayashi in terms of an infinite set of covariant positive operator valued measures (POVM's) and by Bruss and Macchiavello establishing a connection to optimal quantum cloning. An explicit condition for POVM measurement operators for optimal estimators is obtained, by which we construct optimal estimators with finite POVMs using exact quadratures on a hypersphere. These finite optimal estimators are not generally universal, where universality means the fidelity is independent of input states. However, any optimal estimator with finite POVM for M(>N) copies is universal if it is used for N copies as input

  20. Statistical state dynamics-based analysis of the physical mechanisms sustaining and regulating turbulence in Couette flow

    Science.gov (United States)

    Farrell, Brian F.; Ioannou, Petros J.

    2017-08-01

    This paper describes a study of the self-sustaining process in wall turbulence. The study is based on a second order statistical state dynamics model of Couette flow in which the state variables are the streamwise mean flow (first cumulant) and perturbation covariance (second cumulant). This statistical state dynamics model is closed by either setting the third cumulant to zero or by replacing it with a stochastic parametrization. Statistical state dynamics models with this form are referred to as S3T models. S3T models have been shown to self-sustain turbulence with a mean flow and second order perturbation structure similar to that obtained by direct numerical simulation of the equations of motion. The use of a statistical state dynamics model to study the physical mechanisms underlying turbulence has important advantages over the traditional approach of studying the dynamics of individual realizations of turbulence. One advantage is that the analytical structure of S3T statistical state dynamics models isolates the interaction between the mean flow and the perturbation components of the turbulence. Isolation of the interaction between these components reveals how this interaction underlies both the maintenance of the turbulence variance by transfer of energy from the externally driven flow to the perturbation components as well as the enforcement of the observed statistical mean turbulent state by feedback regulation between the mean and perturbation fields. Another advantage of studying turbulence using statistical state dynamics models of S3T form is that the analytical structure of S3T turbulence can be completely characterized. For example, the perturbation component of turbulence in the S3T system is demonstrably maintained by a parametric perturbation growth mechanism in which fluctuation of the mean flow maintains the perturbation field which in turn maintains the mean flow fluctuations in a synergistic interaction. Furthermore, the equilibrium

  1. Uplink Contention-based CSI Feedback with Prioritized Layers for a Multi-Carrier System

    DEFF Research Database (Denmark)

    Kaneko, Megumi; Hayashi, Kazunori; Popovski, Petar

    2012-01-01

    , several works have considered contention-based CSI feedback in the UL control channel. We propose such a feedback scheme for a generic MC system, based on the idea of variable collision protection, where the probability that a feedback information experiences a collision depends on its importance......Optimized resource allocation of the Downlink (DL) in wireless systems utilizing Multi-Carrier (MC) transmission requires Channel State Information (CSI) feedback for each user/subchannel to the Base Station (BS), consuming a high amount of Uplink (UL) radio resources. To alleviate this problem...

  2. Focus on Formative Feedback communication and self-regulated learning – a study in compulsory schools

    DEFF Research Database (Denmark)

    Kirkegaard, Preben Olund

    This study addresses the conceptual challenge of providing students in compulsory schools with good quality formative feedback to enhance self-regulated learning in social interactions. Resent educational research indicates that social communicative interactions in the classroom, with a focus...... qualitative data from video recorded teaching sessions and student group interviews. Methodologically we are inspired by the ethnographical classroom research method. The empirical basis for studying these aspects is data from two compulsory schools in Denmark. This study is a work in progress. Our findings...... on formative feedback, hold the potential to enhance students learning. Self-regulated learning is highly pertinent and can be seen as one of the most import skills for the 21st century learner. We argue that formative feedbackcommunication in interactions is crucial for students to develop self...

  3. Optimization of sensing and feedback control for vibration/flutter of rotating disk by PZT actuators via air coupled pressure.

    Science.gov (United States)

    Yan, Tianhong; Xu, Xinsheng; Han, Jianqiang; Lin, Rongming; Ju, Bingfeng; Li, Qing

    2011-01-01

    In this paper, a feedback control mechanism and its optimization for rotating disk vibration/flutter via changes of air-coupled pressure generated using piezoelectric patch actuators are studied. A thin disk rotates in an enclosure, which is equipped with a feedback control loop consisting of a micro-sensor, a signal processor, a power amplifier, and several piezoelectric (PZT) actuator patches distributed on the cover of the enclosure. The actuator patches are mounted on the inner or the outer surfaces of the enclosure to produce necessary control force required through the airflow around the disk. The control mechanism for rotating disk flutter using enclosure surfaces bonded with sensors and piezoelectric actuators is thoroughly studied through analytical simulations. The sensor output is used to determine the amount of input to the actuator for controlling the response of the disk in a closed loop configuration. The dynamic stability of the disk-enclosure system, together with the feedback control loop, is analyzed as a complex eigenvalue problem, which is solved using Galerkin's discretization procedure. The results show that the disk flutter can be reduced effectively with proper configurations of the control gain and the phase shift through the actuations of PZT patches. The effectiveness of different feedback control methods in altering system characteristics and system response has been investigated. The control capability, in terms of control gain, phase shift, and especially the physical configuration of actuator patches, are also evaluated by calculating the complex eigenvalues and the maximum displacement produced by the actuators. To achieve a optimal control performance, sizes, positions and shapes of PZT patches used need to be optimized and such optimization has been achieved through numerical simulations.

  4. Optimal cloning of mixed Gaussian states

    International Nuclear Information System (INIS)

    Guta, Madalin; Matsumoto, Keiji

    2006-01-01

    We construct the optimal one to two cloning transformation for the family of displaced thermal equilibrium states of a harmonic oscillator, with a fixed and known temperature. The transformation is Gaussian and it is optimal with respect to the figure of merit based on the joint output state and norm distance. The proof of the result is based on the equivalence between the optimal cloning problem and that of optimal amplification of Gaussian states which is then reduced to an optimization problem for diagonal states of a quantum oscillator. A key concept in finding the optimum is that of stochastic ordering which plays a similar role in the purely classical problem of Gaussian cloning. The result is then extended to the case of n to m cloning of mixed Gaussian states

  5. Constrained state-feedback control of an externally excited synchronous machine

    NARCIS (Netherlands)

    Carpiuc, S.C.; Lazar, M.

    2013-01-01

    State-feedback control of externally excited synchronous machines employed in applications such as hybrid electric vehicles and full electric vehicles is a challenging problem. Indeed, these applications are characterized by fast dynamics that are subject to hard physical and control constraints.

  6. How you provide corrective feedback makes a difference: the motivating role of communicating in an autonomy-supporting way.

    Science.gov (United States)

    Mouratidis, Athanasios; Lens, Willy; Vansteenkiste, Maarten

    2010-10-01

    We relied on self-determination theory (SDT; Deci & Ryan, 2000) to investigate to what extent autonomy-supporting corrective feedback (i.e., feedback that coaches communicate to their athletes after poor performance or mistakes) is associated with athletes' optimal motivation and well-being. To test this hypothesis, we conducted a cross-sectional study with 337 (67.1% males) Greek adolescent athletes (age M = 15.59, SD = 2.37) from various sports. Aligned with SDT, we found through path analysis that an autonomy-supporting versus controlling communication style was positively related to future intentions to persist and well-being and negatively related to ill-being. These relations were partially mediated by the perceived legitimacy of the corrective feedback (i.e., the degree of acceptance of corrective feedback), and, in turn, by intrinsic motivation, identified regulation, and external regulation for doing sports. Results indicate that autonomy-supporting feedback can be still motivating even in cases in which such feedback conveys messages of still too low competence.

  7. The Relation of College Student Self-Efficacy toward Writing and Writing Self-Regulation Aptitude: Writing Feedback Perceptions as a Mediating Variable

    Science.gov (United States)

    Ekholm, Eric; Zumbrunn, Sharon; Conklin, Sarah

    2015-01-01

    Despite the powerful effect feedback often has on student writing success more research is needed on how students emotionally react to the feedback they receive. This study tested the predictive and mediational roles of college student writing self-efficacy beliefs and feedback perceptions on writing self-regulation aptitude. Results suggested…

  8. Low-level feedback control for the phase regulation of CLIC Drive Beam Klystrons

    CERN Document Server

    AUTHOR|(SzGeCERN)752526

    2015-01-01

    The requirement of luminosity loss below 1% raises tight tolerances for the phase and power stability of the CLIC drive beam (DB) klystrons and consequently for the high voltage pulse ripple of the modulators. A low-level RF (LLRF) feedback system needs to be developed and combined with the modulator in order to guarantee the phase and amplitude tolerances. To this aim, three feedback control strategies were investigated, i) Proportional Integral (PI) controller, ii) Linear Quadratic Integral Regulator (LQI) and iii) Model Predictive Controller (MPC). The klystron, as well as the incident phase noise were modelled and used for the design and evaluation of the controllers. First simulation results are presented along with future steps and directions.

  9. Fundamental and Subharmonic Resonances of Harmonically Oscillation with Time Delay State Feedback

    Directory of Open Access Journals (Sweden)

    A.F. EL-Bassiouny

    2006-01-01

    Full Text Available Time delays occur in many physical systems. In particular, when automatic control is used with structural or mechanical systems, there exists a delay between measurement of the system state and corrective action. The concept of an equivalent damping related to the delay feedback is proposed and the appropriate choice of the feedback gains and the time delay is discussed from the viewpoint of vibration control. We investigate the fundamental resonance and subharmonic resonance of order one-half of a harmonically oscillation under state feedback control with a time delay. By using the multiple scale perturbation technique, the first order approximation of the resonances are derived and the effect of time delay on the resonances is investigated. The fixed points correspond to a periodic motion for the starting system and we show the external excitation-response and frequency-response curves. We analyze the effect of time delay and the other different parameters on these oscillations.

  10. Feedback reliability calculation for an iterative block decision feedback equalizer

    OpenAIRE

    Huang, G; Nix, AR; Armour, SMD

    2009-01-01

    A new class of iterative block decision feedback equalizer (IB-DFE) was pioneered by Chan and Benvenuto. Unlike the conventional DFE, the IB-DFE is optimized according to the reliability of the feedback (FB) symbols. Since the use of the training sequence (TS) for feedback reliability (FBR) estimation lowers the bandwidth efficiency, FBR estimation without the need for additional TS is of considerable interest. However, prior FBR estimation is limited in the literature to uncoded M-ary phases...

  11. Robust optimal self tuning regulator of nuclear reactors

    International Nuclear Information System (INIS)

    Nouri Khajavi, M.; Menhaj, M.B.; Ghofrani, M.B.

    2000-01-01

    Nuclear power reactors are, in nature nonlinear and time varying. These characteristics must be considered, if large power variations occur in their working regime. In this paper a robust optimal self-tuning regulator for regulating the power of a nuclear reactor has been designed and simulated. The proposed controller is capable of regulating power levels in a wide power range (10% to 100% power levels). The controller achieves a fast and good transient response. The simulation results show that the proposed controller outperforms the fixed optimal control recently cited in the literature for nuclear power plants

  12. Star cluster formation in a turbulent molecular cloud self-regulated by photoionization feedback

    Science.gov (United States)

    Gavagnin, Elena; Bleuler, Andreas; Rosdahl, Joakim; Teyssier, Romain

    2017-12-01

    Most stars in the Galaxy are believed to be formed within star clusters from collapsing molecular clouds. However, the complete process of star formation, from the parent cloud to a gas-free star cluster, is still poorly understood. We perform radiation-hydrodynamical simulations of the collapse of a turbulent molecular cloud using the RAMSES-RT code. Stars are modelled using sink particles, from which we self-consistently follow the propagation of the ionizing radiation. We study how different feedback models affect the gas expulsion from the cloud and how they shape the final properties of the emerging star cluster. We find that the star formation efficiency is lower for stronger feedback models. Feedback also changes the high-mass end of the stellar mass function. Stronger feedback also allows the establishment of a lower density star cluster, which can maintain a virial or sub-virial state. In the absence of feedback, the star formation efficiency is very high, as well as the final stellar density. As a result, high-energy close encounters make the cluster evaporate quickly. Other indicators, such as mass segregation, statistics of multiple systems and escaping stars confirm this picture. Observations of young star clusters are in best agreement with our strong feedback simulation.

  13. Local regulation of interchange turbulence in a dipole-confined plasma torus using current-collection feedback

    International Nuclear Information System (INIS)

    Roberts, T. M.; Mauel, M. E.; Worstell, M. W.

    2015-01-01

    Turbulence in plasma confined by a magnetic dipole is dominated by interchange fluctuations with complex dynamics and short spatial coherence. We report the first use of local current-collection feedback to modify, amplify, and suppress these fluctuations. The spatial extent of turbulence regulation is limited to a correlation length near the collector. Changing the gain and phase of collection results in power either extracted from or injected into the turbulence. The measured plasma response shows some agreement with calculations of the linear response of global interchange-like MHD and entropy modes to current-collection feedback

  14. Model-Based State Feedback Controller Design for a Turbocharged Diesel Engine with an EGR System

    Directory of Open Access Journals (Sweden)

    Tianpu Dong

    2015-05-01

    Full Text Available This paper describes a method for the control of transient exhaust gas recirculation (EGR systems. Firstly, a state space model of the air system is developed by simplifying a mean value model. The state space model is linearized by using linearization theory and validated by the GT-Power data with an operating point of the diesel engine. Secondly, a state feedback controller based on the intake oxygen mass fraction is designed for EGR control. Since direct measurement of the intake oxygen mass fraction is unavailable on the engine, the estimation method for intake oxygen mass fraction has been proposed in this paper. The control strategy is analyzed by using co-simulation with the Matlab/Simulink and GT-Powers software. Finally, the whole control system is experimentally validated against experimental data of a turbocharged diesel engine. The control effect of the state feedback controller compared with PID controller proved to be further verify the feasibility and advantages of the proposed state feedback controller.

  15. Optimization of Sensing and Feedback Control for Vibration/Flutter of Rotating Disk by PZT Actuators via Air Coupled Pressure

    Directory of Open Access Journals (Sweden)

    Bingfeng Ju

    2011-03-01

    Full Text Available In this paper, a feedback control mechanism and its optimization for rotating disk vibration/flutter via changes of air-coupled pressure generated using piezoelectric patch actuators are studied. A thin disk rotates in an enclosure, which is equipped with a feedback control loop consisting of a micro-sensor, a signal processor, a power amplifier, and several piezoelectric (PZT actuator patches distributed on the cover of the enclosure. The actuator patches are mounted on the inner or the outer surfaces of the enclosure to produce necessary control force required through the airflow around the disk. The control mechanism for rotating disk flutter using enclosure surfaces bonded with sensors and piezoelectric actuators is thoroughly studied through analytical simulations. The sensor output is used to determine the amount of input to the actuator for controlling the response of the disk in a closed loop configuration. The dynamic stability of the disk-enclosure system, together with the feedback control loop, is analyzed as a complex eigenvalue problem, which is solved using Galerkin’s discretization procedure. The results show that the disk flutter can be reduced effectively with proper configurations of the control gain and the phase shift through the actuations of PZT patches. The effectiveness of different feedback control methods in altering system characteristics and system response has been investigated. The control capability, in terms of control gain, phase shift, and especially the physical configuration of actuator patches, are also evaluated by calculating the complex eigenvalues and the maximum displacement produced by the actuators. To achieve a optimal control performance, sizes, positions and shapes of PZT patches used need to be optimized and such optimization has been achieved through numerical simulations.

  16. Current control loop design and analysis based on resonant regulators for microgrid applications

    DEFF Research Database (Denmark)

    Federico, de Bosio; Pastorelli, Michelle; de Sousa Ribeiro, Luiz Antonio

    2015-01-01

    Voltage and current control loops play an important role in the performance of microgrids employing power electronics voltage source inverters. Correct design of feedback loops is essential for the proper operation of these systems. This paper analyzes the influence of state feedback cross......-coupling in the design of resonant regulators for inner current loops in power converters operating in standalone microgrids. It is also demonstrated that the effect of state feedback cross-coupling degrades the performance of the control loops by increasing the steady-state error. Different resonant regulators...

  17. Theoretical and experimental studies of optical feedback on solid-state lasers

    International Nuclear Information System (INIS)

    Kervevan, L.

    2006-12-01

    The main objective of this Phd thesis was to implement solid-state lasers based on codoped Yb 3+ :Er 3+ phosphate glasses pumped by laser diode and to study their behavior when submitted to an optical feedback. This kind of lasers presents as main advantages a very high sensibility to the optical feedback due to the optical properties of the Er 3+ ion enhancing the relaxation oscillations. Moreover, the emission wavelength around 1,535 μm belongs to the eye safe spectral domain. First, we have established the rate equations of the population inversion and the electric field for a three-level laser (Yb:Er) submitted to an optical feedback. We have done a comparative study of the influence of the amplifying medium (three-level system Yb:Er or four-level system LNA:Nd) and cavity parameters on the sensitivity due to the optical feedback. The home-made lasers were implemented in optical feedback experiments allowing original measurement of speed, absolute distance or vibration for optical detection of sound restitution. The fourth part of this thesis deals with the behavior a dual frequency laser submitted to a optical feedback. Such a laser oscillates simultaneously on two polarization eigenstates whose optical frequencies are slightly different. The beating mode between these two eigenstates allows self-heterodyne detection. (author)

  18. The optimal location of piezoelectric actuators and sensors for vibration control of plates

    Science.gov (United States)

    Kumar, K. Ramesh; Narayanan, S.

    2007-12-01

    This paper considers the optimal placement of collocated piezoelectric actuator-sensor pairs on a thin plate using a model-based linear quadratic regulator (LQR) controller. LQR performance is taken as objective for finding the optimal location of sensor-actuator pairs. The problem is formulated using the finite element method (FEM) as multi-input-multi-output (MIMO) model control. The discrete optimal sensor and actuator location problem is formulated in the framework of a zero-one optimization problem. A genetic algorithm (GA) is used to solve the zero-one optimization problem. Different classical control strategies like direct proportional feedback, constant-gain negative velocity feedback and the LQR optimal control scheme are applied to study the control effectiveness.

  19. Assessing Feedback in a Mobile Videogame.

    Science.gov (United States)

    Brand, Leah; Beltran, Alicia; Hughes, Sheryl; O'Connor, Teresia; Baranowski, Janice; Nicklas, Theresa; Chen, Tzu-An; Dadabhoy, Hafza R; Diep, Cassandra S; Buday, Richard; Baranowski, Tom

    2016-06-01

    Player feedback is an important part of serious games, although there is no consensus regarding its delivery or optimal content. "Mommio" is a serious game designed to help mothers motivate their preschoolers to eat vegetables. The purpose of this study was to assess optimal format and content of player feedback for use in "Mommio." The current study posed 36 potential "Mommio" gameplay feedback statements to 20 mothers using a Web survey and interview. Mothers were asked about the meaning and helpfulness of each feedback statement. Several themes emerged upon thematic analysis, including identifying an effective alternative in the case of corrective feedback, avoiding vague wording, using succinct and correct grammar, avoiding provocation of guilt, and clearly identifying why players' game choice was correct or incorrect. Guidelines are proposed for future feedback statements.

  20. Nonlinear observer output-feedback MPC treatment scheduling for HIV

    Directory of Open Access Journals (Sweden)

    Zurakowski Ryan

    2011-05-01

    Full Text Available Abstract Background Mathematical models of the immune response to the Human Immunodeficiency Virus demonstrate the potential for dynamic schedules of Highly Active Anti-Retroviral Therapy to enhance Cytotoxic Lymphocyte-mediated control of HIV infection. Methods In previous work we have developed a model predictive control (MPC based method for determining optimal treatment interruption schedules for this purpose. In this paper, we introduce a nonlinear observer for the HIV-immune response system and an integrated output-feedback MPC approach for implementing the treatment interruption scheduling algorithm using the easily available viral load measurements. We use Monte-Carlo approaches to test robustness of the algorithm. Results The nonlinear observer shows robust state tracking while preserving state positivity both for continuous and discrete measurements. The integrated output-feedback MPC algorithm stabilizes the desired steady-state. Monte-Carlo testing shows significant robustness to modeling error, with 90% success rates in stabilizing the desired steady-state with 15% variance from nominal on all model parameters. Conclusions The possibility of enhancing immune responsiveness to HIV through dynamic scheduling of treatment is exciting. Output-feedback Model Predictive Control is uniquely well-suited to solutions of these types of problems. The unique constraints of state positivity and very slow sampling are addressable by using a special-purpose nonlinear state estimator, as described in this paper. This shows the possibility of using output-feedback MPC-based algorithms for this purpose.

  1. Excited, Proud, and Accomplished: Exploring the Effects of Feedback Supplemented with Web-Based Peer Benchmarking on Self-Regulated Learning in Marketing Classrooms

    Science.gov (United States)

    Raska, David

    2014-01-01

    This research explores and tests the effect of an innovative performance feedback practice--feedback supplemented with web-based peer benchmarking--through a lens of social cognitive framework for self-regulated learning. The results suggest that providing performance feedback with references to exemplary peer output is positively associated with…

  2. Coexisting synchronous and asynchronous states in locally coupled array of oscillators by partial self-feedback control

    Science.gov (United States)

    Bera, Bidesh K.; Ghosh, Dibakar; Parmananda, Punit; Osipov, G. V.; Dana, Syamal K.

    2017-07-01

    We report the emergence of coexisting synchronous and asynchronous subpopulations of oscillators in one dimensional arrays of identical oscillators by applying a self-feedback control. When a self-feedback is applied to a subpopulation of the array, similar to chimera states, it splits into two/more sub-subpopulations coexisting in coherent and incoherent states for a range of self-feedback strength. By tuning the coupling between the nearest neighbors and the amount of self-feedback in the perturbed subpopulation, the size of the coherent and the incoherent sub-subpopulations in the array can be controlled, although the exact size of them is unpredictable. We present numerical evidence using the Landau-Stuart system and the Kuramoto-Sakaguchi phase model.

  3. Consensus of satellite cluster flight using an energy-matching optimal control method

    Science.gov (United States)

    Luo, Jianjun; Zhou, Liang; Zhang, Bo

    2017-11-01

    This paper presents an optimal control method for consensus of satellite cluster flight under a kind of energy matching condition. Firstly, the relation between energy matching and satellite periodically bounded relative motion is analyzed, and the satellite energy matching principle is applied to configure the initial conditions. Then, period-delayed errors are adopted as state variables to establish the period-delayed errors dynamics models of a single satellite and the cluster. Next a novel satellite cluster feedback control protocol with coupling gain is designed, so that the satellite cluster periodically bounded relative motion consensus problem (period-delayed errors state consensus problem) is transformed to the stability of a set of matrices with the same low dimension. Based on the consensus region theory in the research of multi-agent system consensus issues, the coupling gain can be obtained to satisfy the requirement of consensus region and decouple the satellite cluster information topology and the feedback control gain matrix, which can be determined by Linear quadratic regulator (LQR) optimal method. This method can realize the consensus of satellite cluster period-delayed errors, leading to the consistency of semi-major axes (SMA) and the energy-matching of satellite cluster. Then satellites can emerge the global coordinative cluster behavior. Finally the feasibility and effectiveness of the present energy-matching optimal consensus for satellite cluster flight is verified through numerical simulations.

  4. Optimally cloned binary coherent states

    DEFF Research Database (Denmark)

    Mueller, C. R.; Leuchs, G.; Marquardt, Ch

    2017-01-01

    their quantum-optimal clones. We analyze the Wigner function and the cumulants of the clones, and we conclude that optimal cloning of binary coherent states requires a nonlinearity above second order. We propose several practical and near-optimal cloning schemes and compare their cloning fidelity to the optimal...

  5. Smart environment architecture for emotion detection and regulation.

    Science.gov (United States)

    Fernández-Caballero, Antonio; Martínez-Rodrigo, Arturo; Pastor, José Manuel; Castillo, José Carlos; Lozano-Monasor, Elena; López, María T; Zangróniz, Roberto; Latorre, José Miguel; Fernández-Sotos, Alicia

    2016-12-01

    This paper introduces an architecture as a proof-of-concept for emotion detection and regulation in smart health environments. The aim of the proposal is to detect the patient's emotional state by analysing his/her physiological signals, facial expression and behaviour. Then, the system provides the best-tailored actions in the environment to regulate these emotions towards a positive mood when possible. The current state-of-the-art in emotion regulation through music and colour/light is implemented with the final goal of enhancing the quality of life and care of the subject. The paper describes the three main parts of the architecture, namely "Emotion Detection", "Emotion Regulation" and "Emotion Feedback Control". "Emotion Detection" works with the data captured from the patient, whereas "Emotion Regulation" offers him/her different musical pieces and colour/light settings. "Emotion Feedback Control" performs as a feedback control loop to assess the effect of emotion regulation over emotion detection. We are currently testing the overall architecture and the intervention in real environments to achieve our final goal. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. Distributed Wireless Power Transfer With Energy Feedback

    Science.gov (United States)

    Lee, Seunghyun; Zhang, Rui

    2017-04-01

    Energy beamforming (EB) is a key technique for achieving efficient radio-frequency (RF) transmission enabled wireless energy transfer (WET). By optimally designing the waveforms from multiple energy transmitters (ETs) over the wireless channels, they can be constructively combined at the energy receiver (ER) to achieve an EB gain that scales with the number of ETs. However, the optimal design of EB waveforms requires accurate channel state information (CSI) at the ETs, which is challenging to obtain practically, especially in a distributed system with ETs at separate locations. In this paper, we study practical and efficient channel training methods to achieve optimal EB in a distributed WET system. We propose two protocols with and without centralized coordination, respectively, where distributed ETs either sequentially or in parallel adapt their transmit phases based on a low-complexity energy feedback from the ER. The energy feedback only depends on the received power level at the ER, where each feedback indicates one particular transmit phase that results in the maximum harvested power over a set of previously used phases. Simulation results show that the two proposed training protocols converge very fast in practical WET systems even with a large number of distributed ETs, while the protocol with sequential ET phase adaptation is also analytically shown to converge to the optimal EB design with perfect CSI by increasing the training time. Numerical results are also provided to evaluate the performance of the proposed distributed EB and training designs as compared to other benchmark schemes.

  7. A state variable approach to the BESSY II local beam-position-feedback system

    International Nuclear Information System (INIS)

    Gilpatrick, J.D.; Khan, S.; Kraemer, D.

    1996-01-01

    At the BESSY II facility, stability of the electron beam position and angle near insertion devices (IDs) is of utmost importance. Disturbances due to ground motion could result in unwanted broad-bandwidth beam-jitter which decreases the electron (and resultant photon) beam's effective brightness. Therefore, feedback techniques must be used. Operating over a frequency range of 100-Hz, a local feedback system will correct these beam-trajectory errors using the four bumps around IDs. This paper reviews how the state-variable feedback approach can be applied to real-time correction of these beam position and angle errors. A frequency-domain solution showing beam jitter reduction is presented. Finally, this paper reports results of a beam-feedback test at BESSY I

  8. Feedback System Control Optimized Electrospinning for Fabrication of an Excellent Superhydrophobic Surface.

    Science.gov (United States)

    Yang, Jian; Liu, Chuangui; Wang, Boqian; Ding, Xianting

    2017-10-13

    Superhydrophobic surface, as a promising micro/nano material, has tremendous applications in biological and artificial investigations. The electrohydrodynamics (EHD) technique is a versatile and effective method for fabricating micro- to nanoscale fibers and particles from a variety of materials. A combination of critical parameters, such as mass fraction, ratio of N, N-Dimethylformamide (DMF) to Tetrahydrofuran (THF), inner diameter of needle, feed rate, receiving distance, applied voltage as well as temperature, during electrospinning process, to determine the morphology of the electrospun membranes, which in turn determines the superhydrophobic property of the membrane. In this study, we applied a recently developed feedback system control (FSC) scheme for rapid identification of the optimal combination of these controllable parameters to fabricate superhydrophobic surface by one-step electrospinning method without any further modification. Within five rounds of experiments by testing totally forty-six data points, FSC scheme successfully identified an optimal parameter combination that generated electrospun membranes with a static water contact angle of 160 degrees or larger. Scanning electron microscope (SEM) imaging indicates that the FSC optimized surface attains unique morphology. The optimized setup introduced here therefore serves as a one-step, straightforward, and economic approach to fabricate superhydrophobic surface with electrospinning approach.

  9. The rice YABBY1 gene is involved in the feedback regulation of gibberellin metabolism.

    Science.gov (United States)

    Dai, Mingqiu; Zhao, Yu; Ma, Qian; Hu, Yongfeng; Hedden, Peter; Zhang, Qifa; Zhou, Dao-Xiu

    2007-05-01

    Gibberellin (GA) biosynthesis is regulated by feedback control providing a mechanism for GA homeostasis in plants. However, regulatory elements involved in the feedback control are not known. In this report, we show that a rice (Oryza sativa) YABBY1 (YAB1) gene had a similar expression pattern as key rice GA biosynthetic genes GA3ox2 and GA20ox2. Overexpression of YAB1 in transgenic rice resulted in a semidwarf phenotype that could be fully rescued by applied GA. Quantification of the endogenous GA content revealed increases of GA(20) and decreases of GA(1) levels in the overexpression plants, in which the transcripts of the biosynthetic gene GA3ox2 were decreased. Cosuppression of YAB1 in transgenic plants induced expression of GA3ox2. The repression of GA3ox2 could be obtained upon treatment by dexamethasone of transgenic plants expressing a YAB1-glucocorticoid receptor fusion. Importantly, we show that YAB1 bound to a GA-responsive element within the GA3ox2 promoter. In addition, the expression of YAB1 was deregulated in GA biosynthesis and signaling mutants and could be either transiently induced by GA or repressed by a GA inhibitor. Finally, either overexpression or cosuppression of YAB1 impaired GA-mediated repression of GA3ox2. These data together suggest that YAB1 is involved in the feedback regulation of GA biosynthesis in rice.

  10. Transcriptional feedback regulation of YUCCA genes in response to auxin levels in Arabidopsis.

    Science.gov (United States)

    Suzuki, Masashi; Yamazaki, Chiaki; Mitsui, Marie; Kakei, Yusuke; Mitani, Yuka; Nakamura, Ayako; Ishii, Takahiro; Soeno, Kazuo; Shimada, Yukihisa

    2015-08-01

    The IPyA pathway, the major auxin biosynthesis pathway, is transcriptionally regulated through a negative feedback mechanism in response to active auxin levels. The phytohormone auxin plays an important role in plant growth and development, and levels of active free auxin are determined by biosynthesis, conjugation, and polar transport. Unlike conjugation and polar transport, little is known regarding the regulatory mechanism of auxin biosynthesis. We discovered that expression of genes encoding indole-3-pyruvic acid (IPyA) pathway enzymes is regulated by elevated or reduced active auxin levels. Expression levels of TAR2, YUC1, YUC2, YUC4, and YUC6 were downregulated in response to synthetic auxins [1-naphthaleneacetic acid (NAA) and 2,4-dichlorophenoxyacetic acid (2,4-D)] exogenously applied to Arabidopsis thaliana L. seedlings. Concomitantly, reduced levels of endogenous indole-3-acetic acid (IAA) were observed. Alternatively, expression of these YUCCA genes was upregulated by the auxin biosynthetic inhibitor kynurenine in Arabidopsis seedlings, accompanied by reduced IAA levels. These results indicate that expression of YUCCA genes is regulated by active auxin levels. Similar results were also observed in auxin-overproduction and auxin-deficient mutants. Exogenous application of IPyA to Arabidopsis seedlings preincubated with kynurenine increased endogenous IAA levels, while preincubation with 2,4-D reduced endogenous IAA levels compared to seedlings exposed only to IPyA. These results suggest that in vivo conversion of IPyA to IAA was enhanced under reduced auxin levels, while IPyA to IAA conversion was depressed in the presence of excess auxin. Based on these results, we propose that the IPyA pathway is transcriptionally regulated through a negative feedback mechanism in response to active auxin levels.

  11. Bayesian feedback versus Markovian feedback in a two-level atom

    International Nuclear Information System (INIS)

    Wiseman, H.M.; Mancini, Stefano; Wang Jin

    2002-01-01

    We compare two different approaches to the control of the dynamics of a continuously monitored open quantum system. The first is Markovian feedback, as introduced in quantum optics by Wiseman and Milburn [Phys. Rev. Lett. 70, 548 (1993)]. The second is feedback based on an estimate of the system state, developed recently by Doherty and Jacobs [Phys. Rev. A 60, 2700 (1999)]. Here we choose to call it, for brevity, Bayesian feedback. For systems with nonlinear dynamics, we expect these two methods of feedback control to give markedly different results. The simplest possible nonlinear system is a driven and damped two-level atom, so we choose this as our model system. The monitoring is taken to be homodyne detection of the atomic fluorescence, and the control is by modulating the driving. The aim of the feedback in both cases is to stabilize the internal state of the atom as close as possible to an arbitrarily chosen pure state, in the presence of inefficient detection and other forms of decoherence. Our results (obtained without recourse to stochastic simulations) prove that Bayesian feedback is never inferior, and is usually superior, to Markovian feedback. However, it would be far more difficult to implement than Markovian feedback and it loses its superiority when obvious simplifying approximations are made. It is thus not clear which form of feedback would be better in the face of inevitable experimental imperfections

  12. Notions of local controllability and optimal feedforward control for quantum systems

    International Nuclear Information System (INIS)

    Chakrabarti, Raj

    2011-01-01

    Local controllability is an essential concept for regulation and control of time-varying nonlinear dynamical systems; in the classical control logic it is at the foundation of neighboring optimal feedback and feedforward control. We introduce notions of local controllability suited to feedforward control of classical input disturbances in bilinear quantum systems evolving on projective spaces and Lie groups. Tests for local controllability based on a Gramian matrix analogous to the nonlinear local controllability Gramian, which allow assessment of which trajectories can be regulated by perturbative feedforward in the presence of classical input noise, are presented. These notions explicitly incorporate system bilinearity and the geometry of quantum states into the definition of local controllability of quantum systems. Associated feedforward strategies are described.

  13. Notions of local controllability and optimal feedforward control for quantum systems

    Energy Technology Data Exchange (ETDEWEB)

    Chakrabarti, Raj, E-mail: rchakra@purdue.edu [School of Chemical Engineering, Purdue University, West Lafayette, IN 47907 (United States)

    2011-05-06

    Local controllability is an essential concept for regulation and control of time-varying nonlinear dynamical systems; in the classical control logic it is at the foundation of neighboring optimal feedback and feedforward control. We introduce notions of local controllability suited to feedforward control of classical input disturbances in bilinear quantum systems evolving on projective spaces and Lie groups. Tests for local controllability based on a Gramian matrix analogous to the nonlinear local controllability Gramian, which allow assessment of which trajectories can be regulated by perturbative feedforward in the presence of classical input noise, are presented. These notions explicitly incorporate system bilinearity and the geometry of quantum states into the definition of local controllability of quantum systems. Associated feedforward strategies are described.

  14. Optimizing Combinations of Flavonoids Deriving from Astragali Radix in Activating the Regulatory Element of Erythropoietin by a Feedback System Control Scheme

    Directory of Open Access Journals (Sweden)

    Hui Yu

    2013-01-01

    Full Text Available Identifying potent drug combination from a herbal mixture is usually quite challenging, due to a large number of possible trials. Using an engineering approach of the feedback system control (FSC scheme, we identified the potential best combinations of four flavonoids, including formononetin, ononin, calycosin, and calycosin-7-O-β-D-glucoside deriving from Astragali Radix (AR; Huangqi, which provided the best biological action at minimal doses. Out of more than one thousand possible combinations, only tens of trials were required to optimize the flavonoid combinations that stimulated a maximal transcriptional activity of hypoxia response element (HRE, a critical regulator for erythropoietin (EPO transcription, in cultured human embryonic kidney fibroblast (HEK293T. By using FSC scheme, 90% of the work and time can be saved, and the optimized flavonoid combinations increased the HRE mediated transcriptional activity by ~3-fold as compared with individual flavonoid, while the amount of flavonoids was reduced by ~10-fold. Our study suggests that the optimized combination of flavonoids may have strong effect in activating the regulatory element of erythropoietin at very low dosage, which may be used as new source of natural hematopoietic agent. The present work also indicates that the FSC scheme is able to serve as an efficient and model-free approach to optimize the drug combination of different ingredients within a herbal decoction.

  15. Feedback Valence Affects Auditory Perceptual Learning Independently of Feedback Probability

    Science.gov (United States)

    Amitay, Sygal; Moore, David R.; Molloy, Katharine; Halliday, Lorna F.

    2015-01-01

    Previous studies have suggested that negative feedback is more effective in driving learning than positive feedback. We investigated the effect on learning of providing varying amounts of negative and positive feedback while listeners attempted to discriminate between three identical tones; an impossible task that nevertheless produces robust learning. Four feedback conditions were compared during training: 90% positive feedback or 10% negative feedback informed the participants that they were doing equally well, while 10% positive or 90% negative feedback informed them they were doing equally badly. In all conditions the feedback was random in relation to the listeners’ responses (because the task was to discriminate three identical tones), yet both the valence (negative vs. positive) and the probability of feedback (10% vs. 90%) affected learning. Feedback that informed listeners they were doing badly resulted in better post-training performance than feedback that informed them they were doing well, independent of valence. In addition, positive feedback during training resulted in better post-training performance than negative feedback, but only positive feedback indicating listeners were doing badly on the task resulted in learning. As we have previously speculated, feedback that better reflected the difficulty of the task was more effective in driving learning than feedback that suggested performance was better than it should have been given perceived task difficulty. But contrary to expectations, positive feedback was more effective than negative feedback in driving learning. Feedback thus had two separable effects on learning: feedback valence affected motivation on a subjectively difficult task, and learning occurred only when feedback probability reflected the subjective difficulty. To optimize learning, training programs need to take into consideration both feedback valence and probability. PMID:25946173

  16. Deterministic and stochastic control of chimera states in delayed feedback oscillator

    Energy Technology Data Exchange (ETDEWEB)

    Semenov, V. [Department of Physics, Saratov State University, Astrakhanskaya Str. 83, 410012 Saratov (Russian Federation); Zakharova, A.; Schöll, E. [Institut für Theoretische Physik, TU Berlin, Hardenbergstraße 36, 10623 Berlin (Germany); Maistrenko, Y. [Institute of Mathematics and Center for Medical and Biotechnical Research, NAS of Ukraine, Tereschenkivska Str. 3, 01601 Kyiv (Ukraine)

    2016-06-08

    Chimera states, characterized by the coexistence of regular and chaotic dynamics, are found in a nonlinear oscillator model with negative time-delayed feedback. The control of these chimera states by external periodic forcing is demonstrated by numerical simulations. Both deterministic and stochastic external periodic forcing are considered. It is shown that multi-cluster chimeras can be achieved by adjusting the external forcing frequency to appropriate resonance conditions. The constructive role of noise in the formation of a chimera states is shown.

  17. Optimization of preventive maintenance cycle based on experimental feedback in nuclear power plants

    International Nuclear Information System (INIS)

    Shi Jie

    2010-01-01

    The preventive replacement method based on the experimental feedback was introduced. In this method, the initial preventive replacement cycle was acquired by expert votes. The preventive replacement cycle combined with the operation experience of the equipment was gained by means of Bayesian theorem. The Optimized preventive replacement cycle can be acquired by comparing the two probabilities that no fault occurs within the cycle. This method was tested on the switches which were used in Daya Bay Nuclear Power Plant and the results indicated its validity. (authors)

  18. Optimality with feedback control in relativistic dynamics of a mass point. Part 1

    International Nuclear Information System (INIS)

    Blaquiere, A.; Pauchard, M.; Tahri-Yousfi, N.; Wickers, D.

    1984-01-01

    This article is an account of part of a research task currently in progress; it deals with relativistic dynamics of a mass-point from the point of view of the theory of optimal feedback control. In the first part, the theoretical frame is presented with an application to the case of special Relativity. This application shows that the way followed in this article is a natural one for approaching Wave mechanics, and that it closely parallels the way along which Louis de Broglie introduced Wave mechanics [fr

  19. Synthesis of state observer and nonlinear output feedback controller design of AC machines

    International Nuclear Information System (INIS)

    Al-Tahir, Ali Abdul Razzaq

    2016-01-01

    The research work developed in this thesis has been mainly devoted to the observation and sensor-less control problems of electrical systems. Three major contributions have been carried out using the high - gain concept and output feedback adaptive nonlinear control for online UPS. In this thesis, we dealt with synthesis of sampled high - gain observers for nonlinear systems application to PMSMs and DFIGs. We particularly focus on two constraints: sampling effect and tracking unmeasured mechanical and magnetic state variables. The first contribution consists in a high gain observer design that performs a relatively accurate estimation of both mechanical and magnetic state variable using the available measurements on stator currents and voltages of PMSM. We propose a global exponential observer having state predictor for a class of nonlinear globally Lipschitz system. In second contribution, we proposed a novel non - standard HGO design for non-injective feedback relation application to variable speed DFIG based WPGS. Meanwhile, a reduced system model is analyzed, provided by observability test to check is it possible synthesis state observer for sensor-less control. In last contribution, an adaptive observer for states and parameters estimation are designed for a class of state - affine systems application to output feedback adaptive nonlinear control of three-phase AC/DC boost power converter for online UPS systems. Basically, the problem focused on cascade nonlinear adaptive controller that is developed making use Lyapunov theory. The parameters uncertainties are processed by the practical control laws under back-stepping design techniques with capacity of adaptation. (author)

  20. Role of Feedback Regulation of Pantothenate Kinase (CoaA) in Control of Coenzyme A Levels in Escherichia coli

    Science.gov (United States)

    Rock, Charles O.; Park, Hee-Won; Jackowski, Suzanne

    2003-01-01

    Pantothenate kinase (CoaA) is a key regulator of coenzyme A (CoA) biosynthesis in Escherichia coli, and its activity is controlled by feedback inhibition by CoA and its thioesters. The importance of feedback inhibition in the control of the intracellular CoA levels was tested by constructing three site-directed mutants of CoaA that were predicted to be feedback resistant based on the crystal structure of the CoaA-CoA binary complex. CoaA[R106A], CoaA[H177Q], and CoaA[F247V] were purified and shown to retain significant catalytic activity and be refractory to inhibition by CoA. CoaA[R106A] retained 50% of the catalytic activity of CoaA, whereas the CoaA[H177Q] and CoaA[F247V] mutants were less active. The importance of feedback control of CoaA to the intracellular CoA levels was assessed by expressing either CoaA or CoaA[R106A] in strain ANS3 [coaA15(Ts) panD2]. Cells expressing CoaA[R106A] had significantly higher levels of phosphorylated pantothenate-derived metabolites and CoA in vivo and excreted significantly more 4′-phosphopantetheine into the medium compared to cells expressing the wild-type protein. These data illustrate the key role of feedback regulation of pantothenate kinase in the control of intracellular CoA levels. PMID:12754240

  1. A Complete Parametric Solutions of Eigenstructure Assignment by State-Derivative Feedback for Linear Control Systems

    Directory of Open Access Journals (Sweden)

    T. H. S. Abdelaziz

    2005-01-01

    Full Text Available In this paper we introduce a complete parametric approach for solving the problem of eigenstructure assignment via state-derivative feedback for linear systems. This problem is always solvable for any controllable systems iff the open-loop system matrix is nonsingular. In this work, two parametric solutions to the feedback gain matrix are introduced that describe the available degrees of freedom offered by the state-derivative feedback in selecting the associated eigenvectors from an admissible class. These freedoms can be utilized to improve robustness of the closed-loop system. Accordingly, the sensitivity of the assigned eigenvalues to perturbations in the system and gain matrix is minimized. Numerical examples are included to show the effectiveness of the proposed approach. 

  2. Combining support vector machines with linear quadratic regulator adaptation for the online design of an automotive active suspension system

    International Nuclear Information System (INIS)

    Chiou, J-S; Liu, M-T

    2008-01-01

    As a powerful machine-learning approach to pattern recognition problems, the support vector machine (SVM) is known to easily allow generalization. More importantly, it works very well in a high-dimensional feature space. This paper presents a nonlinear active suspension controller which achieves a high level performance by compensating for actuator dynamics. We use a linear quadratic regulator (LQR) to ensure optimal control of nonlinear systems. An LQR is used to solve the problem of state feedback and an SVM is used to address the question of the estimation and examination of the state. These two are then combined and designed in a way that outputs feedback control. The real-time simulation demonstrates that an active suspension using the combined SVM-LQR controller provides passengers with a much more comfortable ride and better road handling

  3. Iterative feedback bio-printing-derived cell-laden hydrogel scaffolds with optimal geometrical fidelity and cellular controllability.

    Science.gov (United States)

    Wang, Ling; Xu, Ming-En; Luo, Li; Zhou, Yongyong; Si, Peijian

    2018-02-12

    For three-dimensional bio-printed cell-laden hydrogel tissue constructs, the well-designed internal porous geometry is tailored to obtain the desired structural and cellular properties. However, significant differences often exist between the designed and as-printed scaffolds because of the inherent characteristics of hydrogels and cells. In this study, an iterative feedback bio-printing (IFBP) approach based on optical coherence tomography (OCT) for the fabrication of cell-laden hydrogel scaffolds with optimal geometrical fidelity and cellular controllability was proposed. A custom-made swept-source OCT (SS-OCT) system was applied to characterize the printed scaffolds quantitatively. Based on the obtained empirical linear formula from the first experimental feedback loop, we defined the most appropriate design constraints and optimized the printing process to improve the geometrical fidelity. The effectiveness of IFBP was verified from the second run using gelatin/alginate hydrogel scaffolds laden with C3A cells. The mismatch of the morphological parameters greatly decreased from 40% to within 7%, which significantly optimized the cell viability, proliferation, and morphology, as well as the representative expression of hepatocyte markers, including CYP3A4 and albumin, of the printed cell-laden hydrogel scaffolds. The demonstrated protocol paves the way for the mass fabrication of cell-laden hydrogel scaffolds, engineered tissues, and scaled-up applications of the 3D bio-printing technique.

  4. A positive feedback regulation of ISL-1 in DLBCL but not in pancreatic β-cells

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Qiao, E-mail: zhangqiao200824@126.com [Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Key Laboratory of Molecular Cardiovascular Sciences (Ministry of Education), Peking University, 38 Xueyuan Road, 100191 Beijing (China); Yang, Zhe, E-mail: zheyang@bjmu.edu.cn [Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Key Laboratory of Molecular Cardiovascular Sciences (Ministry of Education), Peking University, 38 Xueyuan Road, 100191 Beijing (China); Wang, Weiping, E-mail: wwp@bjmu.edu.cn [Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Key Laboratory of Molecular Cardiovascular Sciences (Ministry of Education), Peking University, 38 Xueyuan Road, 100191 Beijing (China); Guo, Ting, E-mail: luckyguoting@bjmu.edu.cn [Department of Gastrointestinal Translation Research, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital, 52 Fucheng Road, 100142 Beijing (China); Jia, Zhuqing, E-mail: zhuqingjia@126.com [Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Key Laboratory of Molecular Cardiovascular Sciences (Ministry of Education), Peking University, 38 Xueyuan Road, 100191 Beijing (China); Ma, Kangtao, E-mail: makangtao11@126.com [Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Key Laboratory of Molecular Cardiovascular Sciences (Ministry of Education), Peking University, 38 Xueyuan Road, 100191 Beijing (China); Zhou, Chunyan, E-mail: chunyanzhou@bjmu.edu.cn [Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Key Laboratory of Molecular Cardiovascular Sciences (Ministry of Education), Peking University, 38 Xueyuan Road, 100191 Beijing (China)

    2014-07-04

    Highlights: • ISL-1 is highly expressed in human pancreatic β-cells and DLBCL. • ISL-1 accelerates the tumorigenesis of DLBCL in vivo. • c-Myc positively regulates ISL-1 expression in DLBCL but not in pancreatic β-cells. • ISL-1 and c-Myc forms an ISL-1/c-Myc transcriptional complex only in DLBCL. • Positive feedback regulation of ISL-1 does not exist in normal pancreatic β-cell. - Abstract: Insulin enhancer binding protein-1 (ISL-1), a LIM-homeodomain transcription factor, has been reported to play essential roles in promoting adult pancreatic β-cells proliferation. Recent studies indicate that ISL-1 may also involve in the occurrence of a variety of tumors. However, whether ISL-1 has any functional effect on tumorigenesis, and what are the differences on ISL-1 function in distinct conditions, are completely unknown. In this study, we found that ISL-1 was highly expressed in human pancreatic β-cells, as well as in diffuse large B cell lymphoma (DLBCL), but to a much less extent in other normal tissues or tumor specimens. Further study revealed that ISL-1 promoted the proliferation of pancreatic β-cells and DLBCL cells, and also accelerated the tumorigenesis of DLBCL in vivo. We also found that ISL-1 could activate c-Myc transcription not only in pancreatic β-cells but also in DLBCL cells. However, a cell-specific feedback regulation was detectable only in DLBCL cells. This auto-regulatory loop was established by the interaction of ISL-1 and c-Myc to form an ISL-1/c-Myc transcriptional complex, and synergistically to promote ISL-1 transcription through binding on the ISL-1 promoter. Taken together, our results demonstrate a positive feedback regulation of ISL-1 in DLBCL but not in pancreatic β-cells, which might result in the functional diversities of ISL-1 in different physiological and pathological processes.

  5. A positive feedback regulation of ISL-1 in DLBCL but not in pancreatic β-cells

    International Nuclear Information System (INIS)

    Zhang, Qiao; Yang, Zhe; Wang, Weiping; Guo, Ting; Jia, Zhuqing; Ma, Kangtao; Zhou, Chunyan

    2014-01-01

    Highlights: • ISL-1 is highly expressed in human pancreatic β-cells and DLBCL. • ISL-1 accelerates the tumorigenesis of DLBCL in vivo. • c-Myc positively regulates ISL-1 expression in DLBCL but not in pancreatic β-cells. • ISL-1 and c-Myc forms an ISL-1/c-Myc transcriptional complex only in DLBCL. • Positive feedback regulation of ISL-1 does not exist in normal pancreatic β-cell. - Abstract: Insulin enhancer binding protein-1 (ISL-1), a LIM-homeodomain transcription factor, has been reported to play essential roles in promoting adult pancreatic β-cells proliferation. Recent studies indicate that ISL-1 may also involve in the occurrence of a variety of tumors. However, whether ISL-1 has any functional effect on tumorigenesis, and what are the differences on ISL-1 function in distinct conditions, are completely unknown. In this study, we found that ISL-1 was highly expressed in human pancreatic β-cells, as well as in diffuse large B cell lymphoma (DLBCL), but to a much less extent in other normal tissues or tumor specimens. Further study revealed that ISL-1 promoted the proliferation of pancreatic β-cells and DLBCL cells, and also accelerated the tumorigenesis of DLBCL in vivo. We also found that ISL-1 could activate c-Myc transcription not only in pancreatic β-cells but also in DLBCL cells. However, a cell-specific feedback regulation was detectable only in DLBCL cells. This auto-regulatory loop was established by the interaction of ISL-1 and c-Myc to form an ISL-1/c-Myc transcriptional complex, and synergistically to promote ISL-1 transcription through binding on the ISL-1 promoter. Taken together, our results demonstrate a positive feedback regulation of ISL-1 in DLBCL but not in pancreatic β-cells, which might result in the functional diversities of ISL-1 in different physiological and pathological processes

  6. Suboptimal Regulation of a Class of Bilinear Interconnected Systems with Finite-Time Sliding Planning Horizons

    Directory of Open Access Journals (Sweden)

    M. de la Sen

    2008-01-01

    Full Text Available This paper focuses on the suboptimization of a class of multivariable discrete-time bilinear systems consisting of interconnected bilinear subsystems with respect to a linear quadratic optimal regulation criterion which involves the use of state weighting terms only. Conditions which ensure the controllability of the overall system are given as a previous requirement for optimization. Three transformations of variables are made on the system equations in order to implement the scheme on an equivalent linear system. This leads to an equivalent representation of the used quadratic performance index that involves the appearance of quadratic weighting terms related to both transformed input and state variables. In this way, a Riccati-matrix sequence, allowing the synthesis of a standard feedback control law, is obtained. Finally, the proposed control scheme is tested on realistic examples.

  7. A capacitor-free CMOS LDO regulator with AC-boosting and active-feedback frequency compensation

    Energy Technology Data Exchange (ETDEWEB)

    Zhou Qianneng; Wang Yongsheng; Lai Fengchang, E-mail: qianneng@hit.edu.c [Microelectronics Center, Harbin Institute of Technology, Harbin 150001 (China)

    2009-04-15

    A capacitor-free CMOS low-dropout (LDO) regulator for system-on-chip (SoC) applications is presented. By adopting AC-boosting and active-feedback frequency compensation (ACB-AFFC), the proposed LDO regulator, which is independent of an off-chip capacitor, provides high closed-loop stability. Moreover, a slew rate enhancement circuit is adopted to increase the slew rate and decrease the output voltage dips when the load current is suddenly switched from low to high. The LDO regulator is designed and fabricated in a 0.6 mum CMOS process. The active silicon area is only 770 x 472 mum{sup 2}. Experimental results show that the total error of the output voltage due to line variation is less than +-0.197%. The load regulation is only 0.35 mV/mA when the load current changes from 0 to 100 mA.

  8. Optimal control of xenon concentration by observer design under reactor model uncertainty

    International Nuclear Information System (INIS)

    Cho, Nam Z.; Yang, Chae Y.; Woo, Hae S.

    1989-01-01

    The state feedback in control theory enjoys many advantages, such as stabilization and improved transient response, which could be beneficially used for control of the xenon oscillation in a power reactor. It is, however, not possible in nuclear reactors to measure the state variables, such as xenon and iodine concentrations. For implementation of the optimal state feedback control law, it is thus necessary to estimate the unmeasurable state variables. This paper uses the Luenberger observer to estimate the xenon and iodine concentrations to be used in a linear quadratic problem with state feedback. To overcome the stiffness problem in reactor kinetics, a singular perturbation method is used

  9. Feedback-Equivalence of Nonlinear Systems with Applications to Power System Equations.

    Science.gov (United States)

    Marino, Riccardo

    The key concept of the dissertation is feedback equivalence among systems affine in control. Feedback equivalence to linear systems in Brunovsky canonical form and the construction of the corresponding feedback transformation are used to: (i) design a nonlinear regulator for a detailed nonlinear model of a synchronous generator connected to an infinite bus; (ii) establish which power system network structures enjoy the feedback linearizability property and design a stabilizing control law for these networks with a constraint on the control space which comes from the use of d.c. lines. It is also shown that the feedback linearizability property allows the use of state feedback to contruct a linear controllable system with a positive definite linear Hamiltonian structure for the uncontrolled part if the state space is even; a stabilizing control law is derived for such systems. Feedback linearizability property is characterized by the involutivity of certain nested distributions for strongly accessible analytic systems; if the system is defined on a manifold M diffeomorphic to the Euclidean space, it is established that the set where the property holds is a submanifold open and dense in M. If an analytic output map is defined, a set of nested involutive distributions can be always defined and that allows the introduction of an observability property which is the dual concept, in some sense, to feedback linearizability: the goal is to investigate when a nonlinear system affine in control with an analytic output map is feedback equivalent to a linear controllable and observable system. Finally a nested involutive structure of distributions is shown to guarantee the existence of a state feedback that takes a nonlinear system affine in control to a single input one, both feedback equivalent to linear controllable systems, preserving one controlled vector field.

  10. Effects of Elicited Reflections combined with Tutor or Peer Feedback on Self-Regulated Learning and Learning Outcomes

    NARCIS (Netherlands)

    Van den Boom, Gerard; Paas, Fred; Van Merriënboer, Jeroen

    2009-01-01

    Van den Boom, G., Paas, F., & Van Merriënboer, J. J. G. (2007). Effects of elicited reflections combined with tutor or peer feedback on self-regulated learning and learning outcomes. Learning and Instruction, 17, 532-548.

  11. Optimization and Control of Cyber-Physical Vehicle Systems

    Directory of Open Access Journals (Sweden)

    Justin M. Bradley

    2015-09-01

    Full Text Available A cyber-physical system (CPS is composed of tightly-integrated computation, communication and physical elements. Medical devices, buildings, mobile devices, robots, transportation and energy systems can benefit from CPS co-design and optimization techniques. Cyber-physical vehicle systems (CPVSs are rapidly advancing due to progress in real-time computing, control and artificial intelligence. Multidisciplinary or multi-objective design optimization maximizes CPS efficiency, capability and safety, while online regulation enables the vehicle to be responsive to disturbances, modeling errors and uncertainties. CPVS optimization occurs at design-time and at run-time. This paper surveys the run-time cooperative optimization or co-optimization of cyber and physical systems, which have historically been considered separately. A run-time CPVS is also cooperatively regulated or co-regulated when cyber and physical resources are utilized in a manner that is responsive to both cyber and physical system requirements. This paper surveys research that considers both cyber and physical resources in co-optimization and co-regulation schemes with applications to mobile robotic and vehicle systems. Time-varying sampling patterns, sensor scheduling, anytime control, feedback scheduling, task and motion planning and resource sharing are examined.

  12. Optimization and Control of Cyber-Physical Vehicle Systems.

    Science.gov (United States)

    Bradley, Justin M; Atkins, Ella M

    2015-09-11

    A cyber-physical system (CPS) is composed of tightly-integrated computation, communication and physical elements. Medical devices, buildings, mobile devices, robots, transportation and energy systems can benefit from CPS co-design and optimization techniques. Cyber-physical vehicle systems (CPVSs) are rapidly advancing due to progress in real-time computing, control and artificial intelligence. Multidisciplinary or multi-objective design optimization maximizes CPS efficiency, capability and safety, while online regulation enables the vehicle to be responsive to disturbances, modeling errors and uncertainties. CPVS optimization occurs at design-time and at run-time. This paper surveys the run-time cooperative optimization or co-optimization of cyber and physical systems, which have historically been considered separately. A run-time CPVS is also cooperatively regulated or co-regulated when cyber and physical resources are utilized in a manner that is responsive to both cyber and physical system requirements. This paper surveys research that considers both cyber and physical resources in co-optimization and co-regulation schemes with applications to mobile robotic and vehicle systems. Time-varying sampling patterns, sensor scheduling, anytime control, feedback scheduling, task and motion planning and resource sharing are examined.

  13. Delayed coherent quantum feedback from a scattering theory and a matrix product state perspective

    Science.gov (United States)

    Guimond, P.-O.; Pletyukhov, M.; Pichler, H.; Zoller, P.

    2017-12-01

    We study the scattering of photons propagating in a semi-infinite waveguide terminated by a mirror and interacting with a quantum emitter. This paradigm constitutes an example of coherent quantum feedback, where light emitted towards the mirror gets redirected back to the emitter. We derive an analytical solution for the scattering of two-photon states, which is based on an exact resummation of the perturbative expansion of the scattering matrix, in a regime where the time delay of the coherent feedback is comparable to the timescale of the quantum emitter’s dynamics. We compare the results with numerical simulations based on matrix product state techniques simulating the full dynamics of the system, and extend the study to the scattering of coherent states beyond the low-power limit.

  14. Collective irrationality and positive feedback.

    Science.gov (United States)

    Nicolis, Stamatios C; Zabzina, Natalia; Latty, Tanya; Sumpter, David J T

    2011-04-26

    Recent experiments on ants and slime moulds have assessed the degree to which they make rational decisions when presented with a number of alternative food sources or shelter. Ants and slime moulds are just two examples of a wide range of species and biological processes that use positive feedback mechanisms to reach decisions. Here we use a generic, experimentally validated model of positive feedback between group members to show that the probability of taking the best of options depends crucially on the strength of feedback. We show how the probability of choosing the best option can be maximized by applying an optimal feedback strength. Importantly, this optimal value depends on the number of options, so that when we change the number of options the preference of the group changes, producing apparent "irrationalities". We thus reinterpret the idea that collectives show "rational" or "irrational" preferences as being a necessary consequence of the use of positive feedback. We argue that positive feedback is a heuristic which often produces fast and accurate group decision-making, but is always susceptible to apparent irrationality when studied under particular experimental conditions.

  15. Collective irrationality and positive feedback.

    Directory of Open Access Journals (Sweden)

    Stamatios C Nicolis

    Full Text Available Recent experiments on ants and slime moulds have assessed the degree to which they make rational decisions when presented with a number of alternative food sources or shelter. Ants and slime moulds are just two examples of a wide range of species and biological processes that use positive feedback mechanisms to reach decisions. Here we use a generic, experimentally validated model of positive feedback between group members to show that the probability of taking the best of options depends crucially on the strength of feedback. We show how the probability of choosing the best option can be maximized by applying an optimal feedback strength. Importantly, this optimal value depends on the number of options, so that when we change the number of options the preference of the group changes, producing apparent "irrationalities". We thus reinterpret the idea that collectives show "rational" or "irrational" preferences as being a necessary consequence of the use of positive feedback. We argue that positive feedback is a heuristic which often produces fast and accurate group decision-making, but is always susceptible to apparent irrationality when studied under particular experimental conditions.

  16. Operating wind turbines in strong wind conditions by using feedforward-feedback control

    International Nuclear Information System (INIS)

    Feng, Ju; Sheng, Wen Zhong

    2014-01-01

    Due to the increasing penetration of wind energy into power systems, it becomes critical to reduce the impact of wind energy on the stability and reliability of the overall power system. In precedent works, Shen and his co-workers developed a re-designed operation schema to run wind turbines in strong wind conditions based on optimization method and standard PI feedback control, which can prevent the typical shutdowns of wind turbines when reaching the cut-out wind speed. In this paper, a new control strategy combing the standard PI feedback control with feedforward controls using the optimization results is investigated for the operation of variable-speed pitch-regulated wind turbines in strong wind conditions. It is shown that the developed control strategy is capable of smoothening the power output of wind turbine and avoiding its sudden showdown at high wind speeds without worsening the loads on rotor and blades

  17. Designing adaptive integral sliding mode control for heart rate regulation during cycle-ergometer exercise using bio-feedback.

    Science.gov (United States)

    Argha, Ahmadreza; Su, Steven W; Nguyen, Hung; Celler, Branko G

    2015-01-01

    This paper considers our developed control system which aims to regulate the exercising subjects' heart rate (HR) to a predefined profile. The controller would be an adaptive integral sliding mode controller. Here it is assumed that the controller commands are interpreted as biofeedback auditory commands. These commands can be heard and implemented by the exercising subject as a part of the control-loop. However, transmitting a feedback signal while the pedals are not in the appropriate position to efficiently exert force may lead to a cognitive disengagement of the user from the feedback controller. To address this problem this paper will employ a different form of control system regarding as "actuator-based event-driven control system". This paper will claim that the developed event-driven controller makes it possible to effectively regulate HR to a predetermined HR profile.

  18. Regulation control and energy management scheme for wireless power transfer

    Science.gov (United States)

    Miller, John M.

    2015-12-29

    Power transfer rate at a charging facility can be maximized by employing a feedback scheme. The state of charge (SOC) and temperature of the regenerative energy storage system (RESS) pack of a vehicle is monitored to determine the load due to the RESS pack. An optimal frequency that cancels the imaginary component of the input impedance for the output signal from a grid converter is calculated from the load of the RESS pack, and a frequency offset f* is made to the nominal frequency f.sub.0 of the grid converter output based on the resonance frequency of a magnetically coupled circuit. The optimal frequency can maximize the efficiency of the power transfer. Further, an optimal grid converter duty ratio d* can be derived from the charge rate of the RESS pack. The grid converter duty ratio d* regulates wireless power transfer (WPT) power level.

  19. Time Optimal Synchronization Procedure and Associated Feedback Loops

    CERN Document Server

    Angoletta, Maria Elena; CERN. Geneva. ATS Department

    2016-01-01

    A procedure to increase the speed of currently used synchronization loops in a synchrotron by an order of magnitude is presented. Beams dynamics constraint imposes an upper limit on excursions in stable phase angle, and the procedure presented exploits this limit to arrive in the synchronized state from an arbitrary initial state in the fastest possible way. Detailed corrector design for beam phase loop, differential frequency loop and final synchronization loop is also presented. Finally, an overview of the synchronization methods currently deployed in some other CERN’s machines is provided, together with a brief comparison with the newly proposed time-optimal algorithm.

  20. Design of an optimal preview controller for linear discrete-time descriptor systems with state delay

    Science.gov (United States)

    Cao, Mengjuan; Liao, Fucheng

    2015-04-01

    In this paper, the linear discrete-time descriptor system with state delay is studied, and a design method for an optimal preview controller is proposed. First, by using the discrete lifting technique, the original system is transformed into a general descriptor system without state delay in form. Then, taking advantage of the first-order forward difference operator, we construct a descriptor augmented error system, including the state vectors of the lifted system, error vectors, and desired target signals. Rigorous mathematical proofs are given for the regularity, stabilisability, causal controllability, and causal observability of the descriptor augmented error system. Based on these, the optimal preview controller with preview feedforward compensation for the original system is obtained by using the standard optimal regulator theory of the descriptor system. The effectiveness of the proposed method is shown by numerical simulation.

  1. Complex dynamics of a Holling type II prey-predator system with state feedback control

    International Nuclear Information System (INIS)

    Jiang Guirong; Lu Qishao; Qian Linning

    2007-01-01

    The complex dynamics of a Holling type II prey-predator system with impulsive state feedback control is studied in both theoretical and numerical ways. The sufficient conditions for the existence and stability of semi-trivial and positive periodic solutions are obtained by using the Poincare map and the analogue of the Poincare criterion. The qualitative analysis shows that the positive periodic solution bifurcates from the semi-trivial solution through a fold bifurcation. The bifurcation diagrams, Lyapunov exponents, and phase portraits are illustrated by an example, in which the chaotic solutions appear via a cascade of period-doubling bifurcations. The superiority of the state feedback control strategy is also discussed

  2. The bantam microRNA acts through Numb to exert cell growth control and feedback regulation of Notch in tumor-forming stem cells in the Drosophila brain.

    Science.gov (United States)

    Wu, Yen-Chi; Lee, Kyu-Sun; Song, Yan; Gehrke, Stephan; Lu, Bingwei

    2017-05-01

    Notch (N) signaling is central to the self-renewal of neural stem cells (NSCs) and other tissue stem cells. Its deregulation compromises tissue homeostasis and contributes to tumorigenesis and other diseases. How N regulates stem cell behavior in health and disease is not well understood. Here we show that N regulates bantam (ban) microRNA to impact cell growth, a process key to NSC maintenance and particularly relied upon by tumor-forming cancer stem cells. Notch signaling directly regulates ban expression at the transcriptional level, and ban in turn feedback regulates N activity through negative regulation of the Notch inhibitor Numb. This feedback regulatory mechanism helps maintain the robustness of N signaling activity and NSC fate. Moreover, we show that a Numb-Myc axis mediates the effects of ban on nucleolar and cellular growth independently or downstream of N. Our results highlight intricate transcriptional as well as translational control mechanisms and feedback regulation in the N signaling network, with important implications for NSC biology and cancer biology.

  3. Optimal state discrimination using particle statistics

    International Nuclear Information System (INIS)

    Bose, S.; Ekert, A.; Omar, Y.; Paunkovic, N.; Vedral, V.

    2003-01-01

    We present an application of particle statistics to the problem of optimal ambiguous discrimination of quantum states. The states to be discriminated are encoded in the internal degrees of freedom of identical particles, and we use the bunching and antibunching of the external degrees of freedom to discriminate between various internal states. We show that we can achieve the optimal single-shot discrimination probability using only the effects of particle statistics. We discuss interesting applications of our method to detecting entanglement and purifying mixed states. Our scheme can easily be implemented with the current technology

  4. Self-regulating and self-evolving particle swarm optimizer

    Science.gov (United States)

    Wang, Hui-Min; Qiao, Zhao-Wei; Xia, Chang-Liang; Li, Liang-Yu

    2015-01-01

    In this article, a novel self-regulating and self-evolving particle swarm optimizer (SSPSO) is proposed. Learning from the idea of direction reversal, self-regulating behaviour is a modified position update rule for particles, according to which the algorithm improves the best position to accelerate convergence in situations where the traditional update rule does not work. Borrowing the idea of mutation from evolutionary computation, self-evolving behaviour acts on the current best particle in the swarm to prevent the algorithm from prematurely converging. The performance of SSPSO and four other improved particle swarm optimizers is numerically evaluated by unimodal, multimodal and rotated multimodal benchmark functions. The effectiveness of SSPSO in solving real-world problems is shown by the magnetic optimization of a Halbach-based permanent magnet machine. The results show that SSPSO has good convergence performance and high reliability, and is well matched to actual problems.

  5. Effects of Informative and Confirmatory Feedback on Brain Activation During Negative Feedback Processing

    Directory of Open Access Journals (Sweden)

    Yeon-Kyoung eWoo

    2015-06-01

    Full Text Available The current study compared the effects of informative and confirmatory feedback on brain activation during negative feedback processing. For confirmatory feedback trials, participants were informed that they had failed the task, whereas informative feedback trials presented task relevant information along with the notification of their failure. Fourteen male undergraduates performed a series of spatial-perceptual tasks and received feedback while their brain activity was recorded. During confirmatory feedback trials, greater activations in the amygdala, dorsal anterior cingulate cortex, and the thalamus (including the habenular were observed in response to incorrect responses. These results suggest that confirmatory feedback induces negative emotional reactions to failure. In contrast, informative feedback trials elicited greater activity in the dorsolateral prefrontal cortex (DLPFC when participants experienced failure. Further psychophysiological interaction (PPI analysis revealed a negative coupling between the DLPFC and the amygdala during informative feedback relative to confirmatory feedback trials. These findings suggest that providing task-relevant information could facilitate implicit down-regulation of negative emotions following failure.

  6. Feedback Regulation of Intracellular Hydrostatic Pressure in Surface Cells of the Lens

    Science.gov (United States)

    Gao, Junyuan; Sun, Xiurong; White, Thomas W.; Delamere, Nicholas A.; Mathias, Richard T.

    2015-01-01

    In wild-type lenses from various species, an intracellular hydrostatic pressure gradient goes from ∼340 mmHg in central fiber cells to 0 mmHg in surface cells. This gradient drives a center-to-surface flow of intracellular fluid. In lenses in which gap-junction coupling is increased, the central pressure is lower, whereas if gap-junction coupling is reduced, the central pressure is higher but surface pressure is always zero. Recently, we found that surface cell pressure was elevated in PTEN null lenses. This suggested disruption of a feedback control system that normally maintained zero surface cell pressure. Our purpose in this study was to investigate and characterize this feedback control system. We measured intracellular hydrostatic pressures in mouse lenses using a microelectrode/manometer-based system. We found that all feedback went through transport by the Na/K ATPase, which adjusted surface cell osmolarity such that pressure was maintained at zero. We traced the regulation of Na/K ATPase activity back to either TRPV4, which sensed positive pressure and stimulated activity, or TRPV1, which sensed negative pressure and inhibited activity. The inhibitory effect of TRPV1 on Na/K pumps was shown to signal through activation of the PI3K/AKT axis. The stimulatory effect of TRPV4 was shown in previous studies to go through a different signal transduction path. Thus, there is a local two-legged feedback control system for pressure in lens surface cells. The surface pressure provides a pedestal on which the pressure gradient sits, so surface pressure determines the absolute value of pressure at each radial location. We speculate that the absolute value of intracellular pressure may set the radial gradient in the refractive index, which is essential for visual acuity. PMID:26536260

  7. Grandfather regulations, new source bias, and state air toxics regulations

    International Nuclear Information System (INIS)

    Levinson, Arik

    1999-01-01

    This paper uses plant-level data from the Census of Manufactures and the variation in toxic air pollution regulations across states to measure the effects of laws that are more stringent for new sources of pollution than for existing sources (so-called 'grandfather' regulations). Of particular interest is the resulting 'new source bias' and its effects on capital vintage and investment. Two industries are examined: commercial printing, which has a local product market; and paint manufacturing, which has a more national market. In general, there seem to be no statistically significant differences in capital vintage or investment between plants in states that grandfather new sources of pollution, plants in states that have no air toxics regulations, and plants in states that regulate both new and existing sources

  8. Design of Gain Scheduling Control Using State Derivative Feedback

    Directory of Open Access Journals (Sweden)

    Lázaro Ismael Hardy Llins

    2017-01-01

    Full Text Available In recent years, the study of systems subject to time-varying parameters has awakened the interest of many researchers. The gain scheduling control strategy guarantees a good performance for systems of this type and also is considered as the simplest to deal with problems of this nature. Moreover, the class of systems in which the state derivative signals are easier to obtain than the state signals, such as in the control for reducing vibrations in a mechanical system, has gained an important hole in control theory. Considering those ideas, we propose sufficient conditions via LMI for designing a gain scheduling controller using state derivative feedback. The D-stability methodology was used for improving the performance of the transitory response. Practical implementation in an active suspension system and comparison with other methods validates the efficiency of the proposed strategy.

  9. State-PID Feedback for Pole Placement of LTI Systems

    Directory of Open Access Journals (Sweden)

    Sarawut Sujitjorn

    2011-01-01

    Full Text Available Pole placement problems are especially important for disturbance rejection and stabilization of dynamical systems and regarded as algebraic inverse eigenvalue problems. In this paper, we propose gain formulae of state feedback through PID-elements to achieve desired pole placement for a delay-free LTI system with single input. Real and complex stable poles can be assigned with the proposed compact gain formulae. Numerical examples show that our proposed gain formulae can be used effectively resulting in very satisfactory responses.

  10. Dynamic analysis of the ethanol fermentation with the impulsive state feedback control

    International Nuclear Information System (INIS)

    Zhao, Zhong; Kong, Yinchang; Chen, Ying

    2016-01-01

    Highlights: • Ethanol fermentation model with the impulsive state feedback control is proposed. • Existence and stability of the order-1 or order-2 periodic solution are investigated. • The complete expression of the order-1 periodic solution is obtained. • Fermentation process can be effectively controlled by monitoring the impulsive period. - Abstract: To keep a sustainable and steady output of ethanol, ethanol fermentation in a bio-reactor with impulsive state feedback control is formulated. The sufficient conditions for existences of order-1 periodic solution and order-2 periodic solution are obtained by using the properties of the periodic solution. The results imply that ethanol fermentation tends to an order-1 periodic solution or order-2 periodic solution. At the same time, we also give the complete expression of the period of the positive period-1 solution. Finally, discussions and numerical simulations are given.

  11. Partially blind instantly decodable network codes for lossy feedback environment

    KAUST Repository

    Sorour, Sameh

    2014-09-01

    In this paper, we study the multicast completion and decoding delay minimization problems for instantly decodable network coding (IDNC) in the case of lossy feedback. When feedback loss events occur, the sender falls into uncertainties about packet reception at the different receivers, which forces it to perform partially blind selections of packet combinations in subsequent transmissions. To determine efficient selection policies that reduce the completion and decoding delays of IDNC in such an environment, we first extend the perfect feedback formulation in our previous works to the lossy feedback environment, by incorporating the uncertainties resulting from unheard feedback events in these formulations. For the completion delay problem, we use this formulation to identify the maximum likelihood state of the network in events of unheard feedback and employ it to design a partially blind graph update extension to the multicast IDNC algorithm in our earlier work. For the decoding delay problem, we derive an expression for the expected decoding delay increment for any arbitrary transmission. This expression is then used to find the optimal policy that reduces the decoding delay in such lossy feedback environment. Results show that our proposed solutions both outperform previously proposed approaches and achieve tolerable degradation even at relatively high feedback loss rates.

  12. A combined stochastic feedforward and feedback control design methodology with application to autoland design

    Science.gov (United States)

    Halyo, Nesim

    1987-01-01

    A combined stochastic feedforward and feedback control design methodology was developed. The objective of the feedforward control law is to track the commanded trajectory, whereas the feedback control law tries to maintain the plant state near the desired trajectory in the presence of disturbances and uncertainties about the plant. The feedforward control law design is formulated as a stochastic optimization problem and is embedded into the stochastic output feedback problem where the plant contains unstable and uncontrollable modes. An algorithm to compute the optimal feedforward is developed. In this approach, the use of error integral feedback, dynamic compensation, control rate command structures are an integral part of the methodology. An incremental implementation is recommended. Results on the eigenvalues of the implemented versus designed control laws are presented. The stochastic feedforward/feedback control methodology is used to design a digital automatic landing system for the ATOPS Research Vehicle, a Boeing 737-100 aircraft. The system control modes include localizer and glideslope capture and track, and flare to touchdown. Results of a detailed nonlinear simulation of the digital control laws, actuator systems, and aircraft aerodynamics are presented.

  13. The Effect of Combination of Video Feedback and Audience Feedback on Social Anxiety: Preliminary Findings.

    Science.gov (United States)

    Chen, Junwen; Mak, Rebecca; Fujita, Satoko

    2015-09-01

    Although video feedback (VF) is shown to improve appraisals of social performance in socially anxious individuals, its impact on state anxiety during a social situation is mixed. The current study investigated the effect of combined video feedback and audience feedback (AF) on self-perceptions of performance and bodily sensations as well as state anxiety pertaining to a speech task. Forty-one socially anxious students were randomly allocated to combined video feedback with audience feedback (VF + AF), video feedback only (VF), audience feedback only (AF), or a control condition. Following a 3-min speech, participants in the VF + AF, VF, and AF conditions watched the videotape of their speech with cognitive preparation in the presence of three confederates who served as audience, and/or received feedback from the confederates, while the control group watched their videotaped speech without cognitive preparation. Both VF + AF and AF conditions improved distorted appraisal of performance and bodily sensations as well as state anxiety. The clinical implications of these findings are discussed. © The Author(s) 2015.

  14. A distal ABA responsive element in AtNCED3 promoter is required for positive feedback regulation of ABA biosynthesis in Arabidopsis.

    Directory of Open Access Journals (Sweden)

    Yan-Zhuo Yang

    Full Text Available The plant hormone abscisic acid (ABA plays a crucial role in plant development and responses to abiotic stresses. Recent studies indicate that a positive feedback regulation by ABA exists in ABA biosynthesis in plants under dehydration stress. To understand the molecular basis of this regulation, we analyzed the cis-elements of the AtNCED3 promoter in Arabidopsis. AtNCED3 encodes the first committed and highly regulated dioxygenase in the ABA biosynthetic pathway. Through delineated and mutagenesis analyses in stable-transformed Arabidopsis, we revealed that a distal ABA responsive element (ABRE: GGCACGTG, -2372 to -2364 bp is required for ABA-induced AtNCED3 expression. By analyzing the AtNCED3 expression in ABRE binding protein ABF3 over-expression transgenic plants and knock-out mutants, we provide evidence that the ABA feedback regulation of AtNCED3 expression is not mediated by ABF3.

  15. A distal ABA responsive element in AtNCED3 promoter is required for positive feedback regulation of ABA biosynthesis in Arabidopsis.

    Science.gov (United States)

    Yang, Yan-Zhuo; Tan, Bao-Cai

    2014-01-01

    The plant hormone abscisic acid (ABA) plays a crucial role in plant development and responses to abiotic stresses. Recent studies indicate that a positive feedback regulation by ABA exists in ABA biosynthesis in plants under dehydration stress. To understand the molecular basis of this regulation, we analyzed the cis-elements of the AtNCED3 promoter in Arabidopsis. AtNCED3 encodes the first committed and highly regulated dioxygenase in the ABA biosynthetic pathway. Through delineated and mutagenesis analyses in stable-transformed Arabidopsis, we revealed that a distal ABA responsive element (ABRE: GGCACGTG, -2372 to -2364 bp) is required for ABA-induced AtNCED3 expression. By analyzing the AtNCED3 expression in ABRE binding protein ABF3 over-expression transgenic plants and knock-out mutants, we provide evidence that the ABA feedback regulation of AtNCED3 expression is not mediated by ABF3.

  16. Optimization of radioprotection in the nuclear power, industrial and medical domains

    International Nuclear Information System (INIS)

    Kalifa, G.

    2002-06-01

    These 3. SFRP days are devoted to the optimization of radioprotection in the context of the evolution of the regulation in this domain with the introduction of the ALARA (as low as reasonably achievable) principle in the public health regulations. First of all, the optimization of radioprotection is a principle of action aiming at elaborating a practical organization of risk taking based on the responsibility of the different actors and leading to an individual and collective management of the radiological risk. These days are oriented towards practical applications of this optimization and in a lesser extend towards the general radioprotection policies and the technical aspects, in particular the operational dosimetry: 1 - Alara bases and regulation: bases of radioprotection optimization; optimization and Belgium regulation: the contribution of the Royal by-law from July 20, 2001; status of the French regulation; 2 - Alara policies in the nuclear power domain: maintenance of PWR reactor vessels: exploratory approach of a joint safety and radioprotection control by the nuclear safety authority; implementation of the Alara approach at the CEA: status and perspectives; optimization of activities and Alara project at EdF; the file for the intervention in radioactive environment: an Alara tool; 3 - practical applications and experience feedback: optimization in interventional vascular radiology unit; forecast evaluation and personnel exposures optimization in the experiment hall of the laser integration line at CESTA; a French system of radioprotection experience feedback for radiological incidents; the European Alara network: a growing up dialogue and improvement structure; 4 - Alara policies in the medical and first aid services: dosimetry of radiodiagnosis personnel; integration of the radioactive waste management organization to the elimination files of hospital wastes; optimization of patient's radioprotection: a calculation approach of the specific risk by sex

  17. A feedback linearization approach to spacecraft control using momentum exchange devices. Ph.D. Thesis

    Science.gov (United States)

    Dzielski, John Edward

    1988-01-01

    Recent developments in the area of nonlinear control theory have shown how coordiante changes in the state and input spaces can be used with nonlinear feedback to transform certain nonlinear ordinary differential equations into equivalent linear equations. These feedback linearization techniques are applied to resolve two problems arising in the control of spacecraft equipped with control moment gyroscopes (CMGs). The first application involves the computation of rate commands for the gimbals that rotate the individual gyroscopes to produce commanded torques on the spacecraft. The second application is to the long-term management of stored momentum in the system of control moment gyroscopes using environmental torques acting on the vehicle. An approach to distributing control effort among a group of redundant actuators is described that uses feedback linearization techniques to parameterize sets of controls which influence a specified subsystem in a desired way. The approach is adapted for use in spacecraft control with double-gimballed gyroscopes to produce an algorithm that avoids problematic gimbal configurations by approximating sets of gimbal rates that drive CMG rotors into desirable configurations. The momentum management problem is stated as a trajectory optimization problem with a nonlinear dynamical constraint. Feedback linearization and collocation are used to transform this problem into an unconstrainted nonlinear program. The approach to trajectory optimization is fast and robust. A number of examples are presented showing applications to the proposed NASA space station.

  18. State-Feedback Control for Fractional-Order Nonlinear Systems Subject to Input Saturation

    Directory of Open Access Journals (Sweden)

    Junhai Luo

    2014-01-01

    Full Text Available We give a state-feedback control method for fractional-order nonlinear systems subject to input saturation. First, a sufficient condition is derived for the asymptotical stability of a class of fractional-order nonlinear systems. Then based on Gronwall-Bellman lemma and a sector bounded condition of the saturation function, a linear state-feed back controller is designed. Finally, two simulation examples are presented to show the validity of the proposed method.

  19. A Systematic Controller Design for a Grid-Connected Inverter with LCL Filter Using a Discrete-Time Integral State Feedback Control and State Observer

    Directory of Open Access Journals (Sweden)

    Seung-Jin Yoon

    2018-02-01

    Full Text Available Inductive-capacitive-inductive (LCL-type filters are currently preferred as a replacement for L-type filters in distributed generation (DG power systems, due to their superior harmonic attenuation capability. However, the third-order dynamics introduced by LCL filters pose a challenge to design a satisfactory controller for such a system. Conventionally, an LCL-filtered grid-connected inverter can be effectively controlled by using a full-state feedback control. However, this control approach requires the measurement of all system state variables, which brings about more complexity for the inverter system. To address this issue, this paper presents a systematic procedure to design an observer-based integral state feedback control for a LCL-filtered grid-connected inverter in the discrete-time domain. The proposed control scheme consists of an integral state feedback controller and a full-state observer which uses the control input, grid-side currents, and grid voltages to predict all the system state variables. Therefore, only the grid-side current sensors and grid voltage sensors are required to implement the proposed control scheme. Due to the discrete-time integrator incorporated in the state feedback controller, the proposed control scheme ensures both the reference tracking and disturbance rejection performance of the inverter system in a practical and simple way. As a result, superior control performance can be achieved by using the reduced number of sensors, which significantly reduces the cost and complexity of the LCL-filtered grid-connected inverter system in DG applications. To verify the practical usefulness of the proposed control scheme, a 2 kW three-phase prototype grid-connected inverter has been constructed, and the proposed control system has been implemented based on 32-bit floating-point digital signal processor (DSP TMS320F28335. The effectiveness of the proposed scheme is demonstrated through the comprehensive simulation

  20. Reserve selection with land market feedbacks.

    Science.gov (United States)

    Butsic, Van; Lewis, David J; Radeloff, Volker C

    2013-01-15

    How to best site reserves is a leading question for conservation biologists. Recently, reserve selection has emphasized efficient conservation: maximizing conservation goals given the reality of limited conservation budgets, and this work indicates that land market can potentially undermine the conservation benefits of reserves by increasing property values and development probabilities near reserves. Here we propose a reserve selection methodology which optimizes conservation given both a budget constraint and land market feedbacks by using a combination of econometric models along with stochastic dynamic programming. We show that amenity based feedbacks can be accounted for in optimal reserve selection by choosing property price and land development models which exogenously estimate the effects of reserve establishment. In our empirical example, we use previously estimated models of land development and property prices to select parcels to maximize coarse woody debris along 16 lakes in Vilas County, WI, USA. Using each lake as an independent experiment, we find that including land market feedbacks in the reserve selection algorithm has only small effects on conservation efficacy. Likewise, we find that in our setting heuristic (minloss and maxgain) algorithms perform nearly as well as the optimal selection strategy. We emphasize that land market feedbacks can be included in optimal reserve selection; the extent to which this improves reserve placement will likely vary across landscapes. Copyright © 2012 Elsevier Ltd. All rights reserved.

  1. A population-feedback control based algorithm for well trajectory optimization using proxy model

    Directory of Open Access Journals (Sweden)

    Javad Kasravi

    2017-04-01

    Full Text Available Wellbore instability is one of the concerns in the field of drilling engineering. This phenomenon is affected by several factors such as azimuth, inclination angle, in-situ stress, mud weight, and rock strength parameters. Among these factors, azimuth, inclination angle, and mud weight are controllable. The objective of this paper is to introduce a new procedure based on elastoplastic theory in wellbore stability solution to determine the optimum well trajectory and global minimum mud pressure required (GMMPR. Genetic algorithm (GA was applied as a main optimization engine that employs proportional feedback controller to obtain the minimum mud pressure required (MMPR. The feedback function repeatedly calculated and updated the error between the simulated and set point of normalized yielded zone area (NYZA. To reduce computation expenses, an artificial neural network (ANN was used as a proxy (surrogate model to approximate the behavior of the actual wellbore model. The methodology was applied to a directional well in southwestern Iranian oilfield. The results demonstrated that the error between the predicted GMMPR and practical safe mud pressure was 4% for elastoplastic method, and 22% for conventional elastic solution.

  2. Mechanisms of Molecular Response in the Optimal Control of Photoisomerization

    International Nuclear Information System (INIS)

    Dietzek, Benjamin; Brueggemann, Ben; Pascher, Torbjoern; Yartsev, Arkady

    2006-01-01

    We report on adaptive feedback control of photoinduced barrierless isomerization of 1,1'-diethyl-2,2'-cyanine in solution. We compare the effect of different fitness parameters and show that optimal control of the absolute yield of isomerization (photoisomer concentration versus excitation photons) can be achieved, while the relative isomerization yield (photoisomer concentration versus number of relaxed excited-state molecules) is unaffected by adaptive feedback control. The temporal structure of the optimized excitation pulses allows one to draw clear mechanistic conclusions showing the critical importance of coherent nuclear motion for the control of isomerization

  3. Constrained quadratic stabilization of discrete-time uncertain nonlinear multi-model systems using piecewise affine state-feedback

    Directory of Open Access Journals (Sweden)

    Olav Slupphaug

    1999-07-01

    Full Text Available In this paper a method for nonlinear robust stabilization based on solving a bilinear matrix inequality (BMI feasibility problem is developed. Robustness against model uncertainty is handled. In different non-overlapping regions of the state-space called clusters the plant is assumed to be an element in a polytope which vertices (local models are affine systems. In the clusters containing the origin in their closure, the local models are restricted to be linear systems. The clusters cover the region of interest in the state-space. An affine state-feedback is associated with each cluster. By utilizing the affinity of the local models and the state-feedback, a set of linear matrix inequalities (LMIs combined with a single nonconvex BMI are obtained which, if feasible, guarantee quadratic stability of the origin of the closed-loop. The feasibility problem is attacked by a branch-and-bound based global approach. If the feasibility check is successful, the Liapunov matrix and the piecewise affine state-feedback are given directly by the feasible solution. Control constraints are shown to be representable by LMIs or BMIs, and an application of the control design method to robustify constrained nonlinear model predictive control is presented. Also, the control design method is applied to a simple example.

  4. Optimizing personalized normative feedback: the use of gender-specific referents.

    Science.gov (United States)

    Lewis, Melissa A; Neighbors, Clayton

    2007-03-01

    Many brief interventions include personalized normative feedback (PNF) using gender-specific or gender-neutral referents. Several theories suggest that information pertaining to more socially proximal referents should have greater influence on one's behavior compared with more socially distal referents. The current research evaluated whether gender specificity of the normative referent employed in PNF related to intervention efficacy. Following baseline assessment, 185 college students (45.2% women) were randomly assigned to one of three intervention conditions: gender-specific feedback, gender-neutral feedback, or assessment-only control. Immediately after completing measures of perceived norms, alcohol consumption, and gender identity, participants in the gender-neutral and gender-specific intervention conditions were provided with computerized information detailing their own drinking behavior, their perceptions of student drinking, and actual student drinking. After a 1-month follow-up, the results indicated that normative feedback was effective in changing perceived norms and reducing alcohol consumption for both intervention groups for women and men. The results provide support, however, for changes in perceived gender-specific norms as a mediator of the effects of normative feedback on reduced drinking behavior for women only. Additionally, gender-specific feedback was found to be more effective for women higher in gender identity, relative to the gender-neutral feedback. A post-assessment follow-up telephone survey administered to assess potential demand characteristics corroborated the intervention effects. Results extend previous research documenting efficacy of computer delivered PNF. Gender specificity and gender identity appear to be important elements to consider for PNF intervention efficacy for women.

  5. Power-MOSFET Voltage Regulator

    Science.gov (United States)

    Miller, W. N.; Gray, O. E.

    1982-01-01

    Ninety-six parallel MOSFET devices with two-stage feedback circuit form a high-current dc voltage regulator that also acts as fully-on solid-state switch when fuel-cell out-put falls below regulated voltage. Ripple voltage is less than 20 mV, transient recovery time is less than 50 ms. Parallel MOSFET's act as high-current dc regulator and switch. Regulator can be used wherever large direct currents must be controlled. Can be applied to inverters, industrial furnaces photovoltaic solar generators, dc motors, and electric autos.

  6. Disturbance Error Reduction in Multivariable Optimal Control Systems

    Directory of Open Access Journals (Sweden)

    Ole A. Solheim

    1983-01-01

    Full Text Available The paper deals with the design of optimal multivariable controllers, using a modified LQR approach. All controllers discussed contain proportional feedback and, in addition, there may be feedforward, integral action or state estimation.

  7. Feedback regulation of an Agrobacterium catalase gene katA involved in Agrobacterium-plant interaction.

    Science.gov (United States)

    Xu, X Q; Li, L P; Pan, S Q

    2001-11-01

    Catalases are known to detoxify H2O2, a major component of oxidative stress imposed on a cell. An Agrobacterium tumefaciens catalase encoded by a chromosomal gene katA has been implicated as an important virulence factor as it is involved in detoxification of H2O2 released during Agrobacterium-plant interaction. In this paper, we report a feedback regulation pathway that controls the expression of katA in A. tumefaciens cells. We observed that katA could be induced by plant tissue sections and by acidic pH on a minimal medium, which resembles the plant environment that the bacteria encounter during the course of infection. This represents a new regulatory factor for catalase induction in bacteria. More importantly, a feedback regulation was observed when the katA-gfp expression was studied in different genetic backgrounds. We found that introduction of a wild-type katA gene encoding a functional catalase into A. tumefaciens cells could repress the katA-gfp expression over 60-fold. The katA gene could be induced by H2O2 and the encoded catalase could detoxify H2O2. In addition, the katA-gfp expression of one bacterial cell could be repressed by other surrounding catalase-proficient bacterial cells. Furthermore, mutation at katA caused a 10-fold increase of the intracellular H2O2 concentration in the bacteria grown on an acidic pH medium. These results suggest that the endogenous H2O2 generated during A. tumefaciens cell growth could serve as the intracellular and intercellular inducer for the katA gene expression and that the acidic pH could pose an oxidative stress on the bacteria. Surprisingly, one mutated KatA protein, exhibiting no significant catalase activity as a result of the alteration of two important residues at the putative active site, could partially repress the katA-gfp expression. The feedback regulation of the katA gene by both catalase activity and KatA protein could presumably maintain an appropriated level of catalase activity and H2O2 inside A

  8. Design an optimal controller for nuclear reactor using a digital computer

    International Nuclear Information System (INIS)

    Saleh, F.M.A.

    1986-01-01

    An attempt is carried out to design an optimal controller, for a model nuclear reactor at one hand, and a model nuclear power plant at another hand using a digital computer. The design philosophy adopted was to specify the system dynamics in terms of a desired system transfer function, and realizing the design synthesis through state-variable feedback technique, thus ensuring both stability and optimization in the state space sense. The control design was also tested by carrying out digital simulation transient response runs (step, ramp, impulse, etc.) and agreement between the predicted desirable response and actual response of the overall design was achieved. Furthermore the performance of the controller is verified against a reference non-linear model for purposes of assessing the accuracy of the linearized approximation model. The results show that state-variable feedback policy can rank as an effective optimal technique for designing control algorithm for an on-line computer of a nuclear power plant. 41 figs. 43 refs

  9. MicroRNA-7/NF-κB signaling regulatory feedback circuit regulates gastric carcinogenesis

    Science.gov (United States)

    Zhao, Xiao-Di; Lu, Yuan-Yuan; Guo, Hao; Xie, Hua-Hong; He, Li-Jie; Shen, Gao-Fei; Zhou, Jin-Feng; Li, Ting; Hu, Si-Jun; Zhou, Lin; Han, Ya-Nan; Liang, Shu-Li; Wang, Xin; Wu, Kai-Chun; Shi, Yong-Quan; Nie, Yong-Zhan

    2015-01-01

    MicroRNAs play essential roles in gene expression regulation during carcinogenesis. Here, we investigated the role of miR-7 and the mechanism by which it is dysregulated in gastric cancer (GC). We used genome-wide screenings and identified RELA and FOS as novel targets of miR-7. Overexpression of miR-7 repressed RELA and FOS expression and prevented GC cell proliferation and tumorigenesis. These effects were clinically relevant, as low miR-7 expression was correlated with high RELA and FOS expression and poor survival in GC patients. Intriguingly, we found that miR-7 indirectly regulated RELA activation by targeting the IκB kinase IKKε. Furthermore, IKKε and RELA can repress miR-7 transcription, which forms a feedback circuit between miR-7 and nuclear factor κB (NF-κB) signaling. Additionally, we demonstrate that down-regulation of miR-7 may occur as a result of the aberrant activation of NF-κB signaling by Helicobacter pylori infection. These findings suggest that miR-7 may serve as an important regulator in GC development and progression. PMID:26261179

  10. Theory and Applications of Discontinuous State Feedback Generating Chaos for Linear Systems

    International Nuclear Information System (INIS)

    Xiao-Dan, Zhang; Zhen, Wang; Pin-Dong, Zhao

    2008-01-01

    We investigate a kind of chaos generating technique on a type of n-dimensional linear differential systems by adding feedback control items under a discontinuous state. This method is checked with some examples of numeric simulation. A constructive theorem is proposed for generalized synchronization related to the above chaotic system

  11. Relaxation rates of gene expression kinetics reveal the feedback signs of autoregulatory gene networks

    Science.gov (United States)

    Jia, Chen; Qian, Hong; Chen, Min; Zhang, Michael Q.

    2018-03-01

    The transient response to a stimulus and subsequent recovery to a steady state are the fundamental characteristics of a living organism. Here we study the relaxation kinetics of autoregulatory gene networks based on the chemical master equation model of single-cell stochastic gene expression with nonlinear feedback regulation. We report a novel relation between the rate of relaxation, characterized by the spectral gap of the Markov model, and the feedback sign of the underlying gene circuit. When a network has no feedback, the relaxation rate is exactly the decaying rate of the protein. We further show that positive feedback always slows down the relaxation kinetics while negative feedback always speeds it up. Numerical simulations demonstrate that this relation provides a possible method to infer the feedback topology of autoregulatory gene networks by using time-series data of gene expression.

  12. Which Feedback Is More Effective for Pursuing Multiple Goals of Differing Importance? The Interaction Effects of Goal Importance and Performance Feedback Type on Self-Regulation and Task Achievement

    Science.gov (United States)

    Lee, Hyunjoo

    2016-01-01

    This study examined how performance feedback type (progress vs. distance) affects Korean college students' self-regulation and task achievement according to relative goal importance in the pursuit of multiple goals. For this study, 146 students participated in a computerised task. The results showed the interaction effects of goal importance and…

  13. Integration of sensory force feedback is disturbed in CRPS-related dystonia.

    Science.gov (United States)

    Mugge, Winfred; van der Helm, Frans C T; Schouten, Alfred C

    2013-01-01

    Complex regional pain syndrome (CRPS) is characterized by pain and disturbed blood flow, temperature regulation and motor control. Approximately 25% of cases develop fixed dystonia. The origin of this movement disorder is poorly understood, although recent insights suggest involvement of disturbed force feedback. Assessment of sensorimotor integration may provide insight into the pathophysiology of fixed dystonia. Sensory weighting is the process of integrating and weighting sensory feedback channels in the central nervous system to improve the state estimate. It was hypothesized that patients with CRPS-related dystonia bias sensory weighting of force and position toward position due to the unreliability of force feedback. The current study provides experimental evidence for dysfunctional sensory integration in fixed dystonia, showing that CRPS-patients with fixed dystonia weight force and position feedback differently than controls do. The study shows reduced force feedback weights in CRPS-patients with fixed dystonia, making it the first to demonstrate disturbed integration of force feedback in fixed dystonia, an important step towards understanding the pathophysiology of fixed dystonia.

  14. Integration of sensory force feedback is disturbed in CRPS-related dystonia.

    Directory of Open Access Journals (Sweden)

    Winfred Mugge

    Full Text Available Complex regional pain syndrome (CRPS is characterized by pain and disturbed blood flow, temperature regulation and motor control. Approximately 25% of cases develop fixed dystonia. The origin of this movement disorder is poorly understood, although recent insights suggest involvement of disturbed force feedback. Assessment of sensorimotor integration may provide insight into the pathophysiology of fixed dystonia. Sensory weighting is the process of integrating and weighting sensory feedback channels in the central nervous system to improve the state estimate. It was hypothesized that patients with CRPS-related dystonia bias sensory weighting of force and position toward position due to the unreliability of force feedback. The current study provides experimental evidence for dysfunctional sensory integration in fixed dystonia, showing that CRPS-patients with fixed dystonia weight force and position feedback differently than controls do. The study shows reduced force feedback weights in CRPS-patients with fixed dystonia, making it the first to demonstrate disturbed integration of force feedback in fixed dystonia, an important step towards understanding the pathophysiology of fixed dystonia.

  15. The Optimization of power reactor control system

    International Nuclear Information System (INIS)

    Danupoyo, S.D.

    1997-01-01

    A power reactor is an important part in nuclear powered electrical plant systems. Success in controlling the power reactor will establish safety of the whole power plant systems. Until now, the power reactor has been controlled by a classical control system that was designed based on output feedback method. To meet the safety requirements that are now more restricted, the recently used power reactor control system should be modified. this paper describes a power reactor control system that is designed based on a state feedback method optimized with LQG (Linear-quadrature-gaussian) method and equipped with a state estimator. A pressurized-water type reactor has been used as the model. by using a point kinetics method with one group delayed neutrons. the result of simulation testing shows that the optimized control system can control the power reactor more effective and efficient than the classical control system

  16. Optimal integral force feedback for active vibration control

    Science.gov (United States)

    Teo, Yik R.; Fleming, Andrew J.

    2015-11-01

    This paper proposes an improvement to Integral Force Feedback (IFF), which is a popular method for active vibration control of structures and mechanical systems. Benefits of IFF include robustness, guaranteed stability and simplicity. However, the maximum damping performance is dependent on the stiffness of the system; hence, some systems cannot be adequately controlled. In this paper, an improvement to the classical force feedback control scheme is proposed. The improved method achieves arbitrary damping for any mechanical system by introducing a feed-through term. The proposed improvement is experimentally demonstrated by actively damping an objective lens assembly for a high-speed confocal microscope.

  17. The Interplay between Feedback and Buffering in Cellular Homeostasis.

    Science.gov (United States)

    Hancock, Edward J; Ang, Jordan; Papachristodoulou, Antonis; Stan, Guy-Bart

    2017-11-22

    Buffering, the use of reservoirs of molecules to maintain concentrations of key molecular species, and negative feedback are the primary known mechanisms for robust homeostatic regulation. To our knowledge, however, the fundamental principles behind their combined effect have not been elucidated. Here, we study the interplay between buffering and negative feedback in the context of cellular homeostasis. We show that negative feedback counteracts slow-changing disturbances, whereas buffering counteracts fast-changing disturbances. Furthermore, feedback and buffering have limitations that create trade-offs for regulation: instability in the case of feedback and molecular noise in the case of buffering. However, because buffering stabilizes feedback and feedback attenuates noise from slower-acting buffering, their combined effect on homeostasis can be synergistic. These effects can be explained within a traditional control theory framework and are consistent with experimental observations of both ATP homeostasis and pH regulation in vivo. These principles are critical for studying robustness and homeostasis in biology and biotechnology. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  18. Comparison of optical feedback dynamics of InAs/GaAs quantum-dot lasers emitting solely on ground or excited states.

    Science.gov (United States)

    Lin, Lyu-Chih; Chen, Chih-Ying; Huang, Heming; Arsenijević, Dejan; Bimberg, Dieter; Grillot, Frédéric; Lin, Fan-Yi

    2018-01-15

    We experimentally compare the dynamics of InAs/GaAs quantum dot lasers under optical feedback emitting exclusively on ground states (GSs) or excited states (ESs). By varying the feedback parameters and putting focus either on their short or long cavity regions, various periodic and chaotic oscillatory states are found. The GS laser is shown to be more resistant to feedback, benefiting from its strong relaxation oscillation damping. In contrast, the ES laser can easily be driven into complex dynamics. While the GS laser is of importance for the development of isolator-free transmitters, the ES laser is essential for applications taking advantages of chaos.

  19. Corresponding Angle Feedback in an innovative weighted transportation system

    International Nuclear Information System (INIS)

    Dong Chuanfei; Ma Xu

    2010-01-01

    The optimal information feedback has a significant effect on many socioeconomic systems like stock market and traffic systems aiming to make full use of resources. In this Letter, we study dynamics of traffic flow with real-time information. The influence of a feedback strategy named Corresponding Angle Feedback Strategy (CAFS) is introduced, based on a two-route scenario in which dynamic information can be generated and displayed on the board to guide road users to make a choice. Our model incorporates the effects of adaptability into the cellular automaton models of traffic flow and simulation results adopting this optimal information feedback strategy have demonstrated high efficiency in controlling spatial distribution of traffic patterns compared with the other three information feedback strategies, i.e., vehicle number and flux.

  20. Perturbed cooperative-state feedback strategy for model predictive networked control of interconnected systems.

    Science.gov (United States)

    Tran, Tri; Ha, Q P

    2018-01-01

    A perturbed cooperative-state feedback (PSF) strategy is presented for the control of interconnected systems in this paper. The subsystems of an interconnected system can exchange data via the communication network that has multiple connection topologies. The PSF strategy can resolve both issues, the sensor data losses and the communication network breaks, thanks to the two components of the control including a cooperative-state feedback and a perturbation variable, e.g., u i =K ij x j +w i . The PSF is implemented in a decentralized model predictive control scheme with a stability constraint and a non-monotonic storage function (ΔV(x(k))≥0), derived from the dissipative systems theory. Numerical simulation for the automatic generation control problem in power systems is studied to illustrate the effectiveness of the presented PSF strategy. Copyright © 2017 ISA. Published by Elsevier Ltd. All rights reserved.

  1. Parameters-tuning of PID controller for automatic voltage regulators using the African buffalo optimization

    Science.gov (United States)

    Mohmad Kahar, Mohd Nizam; Noraziah, A.

    2017-01-01

    In this paper, an attempt is made to apply the African Buffalo Optimization (ABO) to tune the parameters of a PID controller for an effective Automatic Voltage Regulator (AVR). Existing metaheuristic tuning methods have been proven to be quite successful but there were observable areas that need improvements especially in terms of the system’s gain overshoot and steady steady state errors. Using the ABO algorithm where each buffalo location in the herd is a candidate solution to the Proportional-Integral-Derivative parameters was very helpful in addressing these two areas of concern. The encouraging results obtained from the simulation of the PID Controller parameters-tuning using the ABO when compared with the performance of Genetic Algorithm PID (GA-PID), Particle-Swarm Optimization PID (PSO-PID), Ant Colony Optimization PID (ACO-PID), PID, Bacteria-Foraging Optimization PID (BFO-PID) etc makes ABO-PID a good addition to solving PID Controller tuning problems using metaheuristics. PMID:28441390

  2. GDSL LIPASE1 Modulates Plant Immunity through Feedback Regulation of Ethylene Signaling1[W

    Science.gov (United States)

    Kim, Hye Gi; Kwon, Sun Jae; Jang, Young Jin; Nam, Myung Hee; Chung, Joo Hee; Na, Yun-Cheol; Guo, Hongwei; Park, Ohkmae K.

    2013-01-01

    Ethylene is a key signal in the regulation of plant defense responses. It is required for the expression and function of GDSL LIPASE1 (GLIP1) in Arabidopsis (Arabidopsis thaliana), which plays an important role in plant immunity. Here, we explore molecular mechanisms underlying the relationship between GLIP1 and ethylene signaling by an epistatic analysis of ethylene response mutants and GLIP1-overexpressing (35S:GLIP1) plants. We show that GLIP1 expression is regulated by ethylene signaling components and, further, that GLIP1 expression or application of petiole exudates from 35S:GLIP1 plants affects ethylene signaling both positively and negatively, leading to ETHYLENE RESPONSE FACTOR1 activation and ETHYLENE INSENSITIVE3 (EIN3) down-regulation, respectively. Additionally, 35S:GLIP1 plants or their exudates increase the expression of the salicylic acid biosynthesis gene SALICYLIC ACID INDUCTION-DEFICIENT2, known to be inhibited by EIN3 and EIN3-LIKE1. These results suggest that GLIP1 regulates plant immunity through positive and negative feedback regulation of ethylene signaling, and this is mediated by its activity to accumulate a systemic signal(s) in the phloem. We propose a model explaining how GLIP1 regulates the fine-tuning of ethylene signaling and ethylene-salicylic acid cross talk. PMID:24170202

  3. Sensorless State-Space Control of Elastic Two-Inertia Drive System Using a Minimum State Order Observer

    Directory of Open Access Journals (Sweden)

    V. Comnac

    2009-12-01

    Full Text Available The paper presents sensorless state-space control of two-inertia drive system with resilient coupling. The control structure contains an I+PI controller for load speed regulation and a state feedback controller for effective vibration suppression of the elastic coupling. Mechanical state variable of two-inertia drive are obtained by using a linear minimum-order (Gopinath state observer. The design of the combined (I+PI and state feedback controller is achieved with the extended version of the modulus criterion [5]. The dynamic behavior of presented control structure has been examined, for different conditions, using MATLAB/SIMULINK simulation.

  4. Combined Audience and Video Feedback With Cognitive Review Improves State Anxiety and Self-Perceptions During Speech Tasks in Socially Anxious Individuals.

    Science.gov (United States)

    Chen, Junwen; McLean, Jordan E; Kemps, Eva

    2018-03-01

    This study investigated the effects of combined audience feedback with video feedback plus cognitive preparation, and cognitive review (enabling deeper processing of feedback) on state anxiety and self-perceptions including perception of performance and perceived probability of negative evaluation in socially anxious individuals during a speech performance. One hundred and forty socially anxious students were randomly assigned to four conditions: Cognitive Preparation + Video Feedback + Audience Feedback + Cognitive Review (CP+VF+AF+CR), Cognitive Preparation + Video Feedback + Cognitive Review (CP+VF+CR), Cognitive Preparation + Video Feedback only (CP+VF), and Control. They were asked to deliver two impromptu speeches that were evaluated by confederates. Participants' levels of anxiety and self-perceptions pertaining to the speech task were assessed before and after feedback, and after the second speech. Compared to participants in the other conditions, participants in the CP+VF+AF+CR condition reported a significant decrease in their state anxiety and perceived probability of negative evaluation scores, and a significant increase in their positive perception of speech performance from before to after the feedback. These effects generalized to the second speech. Our results suggest that adding audience feedback to video feedback plus cognitive preparation and cognitive review may improve the effects of existing video feedback procedures in reducing anxiety symptoms and distorted self-representations in socially anxious individuals. Copyright © 2017. Published by Elsevier Ltd.

  5. On optimal feedforward and ILC : the role of feedback for optimal performance and inferential control

    NARCIS (Netherlands)

    van Zundert, J.C.D.; Oomen, T.A.E

    2017-01-01

    The combination of feedback control with inverse model feedforward control or iterative learning control is known to yield high performance. The aim of this paper is to clarify the role of feedback in the design of feedforward controllers, with specific attention to the inferential situation. Recent

  6. State-federal interactions in nuclear regulation

    Energy Technology Data Exchange (ETDEWEB)

    Pasternak, A.D.; Budnitz, R.J.

    1987-12-01

    The Atomic Energy Act of 1954 established, and later Congressional amendments have confirmed, that except in areas which have been explicitly granted to the states, the federal government possesses preemptive authority to regulate radiation hazards associated with the development and use of atomic energy. Since the passage of the original Act, numerous decisions by the courts have reaffirmed the legitimacy of federal preemption, and have defined and redefined its scope. In this study, the aim is to explore the underlying issues involved in federal preemption of radiation-hazard regulation, and to recommend actions that the Department of Energy and other agencies and groups should consider undertaking in the near term to protect the preemption principle. Appropriate roles of the states are discussed, as well as recent state-level activities and their rationale, and several current arenas in which state-federal conflicts about regulation of hazards are being played out. The emphasis here is on four particular arenas that are now important arenas of conflict, but the issues discussed are far broader in scope. These four arenas are: state-level moratorium activity; emergency planning for reactors; conflicts arising from state financial regulation; and inroads in federal preemption through litigation under state law.

  7. State-federal interactions in nuclear regulation

    International Nuclear Information System (INIS)

    Pasternak, A.D.; Budnitz, R.J.

    1987-12-01

    The Atomic Energy Act of 1954 established, and later Congressional amendments have confirmed, that except in areas which have been explicitly granted to the states, the federal government possesses preemptive authority to regulate radiation hazards associated with the development and use of atomic energy. Since the passage of the original Act, numerous decisions by the courts have reaffirmed the legitimacy of federal preemption, and have defined and redefined its scope. In this study, the aim is to explore the underlying issues involved in federal preemption of radiation-hazard regulation, and to recommend actions that the Department of Energy and other agencies and groups should consider undertaking in the near term to protect the preemption principle. Appropriate roles of the states are discussed, as well as recent state-level activities and their rationale, and several current arenas in which state-federal conflicts about regulation of hazards are being played out. The emphasis here is on four particular arenas that are now important arenas of conflict, but the issues discussed are far broader in scope. These four arenas are: state-level moratorium activity; emergency planning for reactors; conflicts arising from state financial regulation; and inroads in federal preemption through litigation under state law

  8. Secure Multiple-Antenna Block-Fading Wiretap Channels with Limited CSI Feedback

    KAUST Repository

    Hyadi, Amal

    2017-07-18

    In this paper, we investigate the ergodic secrecy capacity of a block-fading wiretap channel with limited channel knowledge at the transmitter. We consider that the legitimate receiver, the eavesdropper and the transmitter are equipped with multiple antennas and that the receiving nodes are aware of their respective channel matrices. The transmitter, on the other hand, is only provided by a B-bit feedback of the main channel state information. The feedback bits are sent by the legitimate receiver, at the beginning of each fading block, over an error-free public link with limited capacity. The statistics of the main and the eavesdropper channel state information are known at all nodes. Assuming an average transmit power constraint, we establish upper and lower bounds on the ergodic secrecy capacity. Then, we present a framework to design the optimal codebooks for feedback and transmission. In addition, we show that the proposed lower and upper bounds coincide asymptotically as the capacity of the feedback link becomes large, i.e. $B \\ ightarrow \\\\infty$ ; hence, fully characterizing the ergodic secrecy capacity in this case. Besides, we analyze the asymptotic behavior of the presented secrecy rates, at high Signal-to-Noise Ratio (SNR), and evaluate the gap between the bounds.

  9. Secure Multiple-Antenna Block-Fading Wiretap Channels with Limited CSI Feedback

    KAUST Repository

    Hyadi, Amal; Rezki, Zouheir; Alouini, Mohamed-Slim

    2017-01-01

    In this paper, we investigate the ergodic secrecy capacity of a block-fading wiretap channel with limited channel knowledge at the transmitter. We consider that the legitimate receiver, the eavesdropper and the transmitter are equipped with multiple antennas and that the receiving nodes are aware of their respective channel matrices. The transmitter, on the other hand, is only provided by a B-bit feedback of the main channel state information. The feedback bits are sent by the legitimate receiver, at the beginning of each fading block, over an error-free public link with limited capacity. The statistics of the main and the eavesdropper channel state information are known at all nodes. Assuming an average transmit power constraint, we establish upper and lower bounds on the ergodic secrecy capacity. Then, we present a framework to design the optimal codebooks for feedback and transmission. In addition, we show that the proposed lower and upper bounds coincide asymptotically as the capacity of the feedback link becomes large, i.e. $B \\rightarrow \\infty$ ; hence, fully characterizing the ergodic secrecy capacity in this case. Besides, we analyze the asymptotic behavior of the presented secrecy rates, at high Signal-to-Noise Ratio (SNR), and evaluate the gap between the bounds.

  10. The Optimal Regulation of Product Quality under Monopoly

    OpenAIRE

    Hans Zenger

    2006-01-01

    This paper characterizes the optimal quality regulation of a monopolist when quality is observable. In contrast to Sheshinski (1976) it is shown that a minimum quality standard may be desirable even if it induces the firm to reduce output.

  11. Fast feedback for linear colliders

    International Nuclear Information System (INIS)

    Hendrickson, L.; Adolphsen, C.; Allison, S.; Gromme, T.; Grossberg, P.; Himel, T.; Krauter, K.; MacKenzie, R.; Minty, M.; Sass, R.

    1995-01-01

    A fast feedback system provides beam stabilization for the SLC. As the SLC is in some sense a prototype for future linear colliders, this system may be a prototype for future feedbacks. The SLC provides a good base of experience for feedback requirements and capabilities as well as a testing ground for performance characteristics. The feedback system controls a wide variety of machine parameters throughout the SLC and associated experiments, including regulation of beam position, angle, energy, intensity and timing parameters. The design and applications of the system are described, in addition to results of recent performance studies

  12. Regulation of Viable and Optimal Cohorts

    Energy Technology Data Exchange (ETDEWEB)

    Aubin, Jean-Pierre, E-mail: aubin.jp@gmail.com [VIMADES (Viabilité, Marchés, Automatique, Décisions) (France)

    2015-10-15

    This study deals with the evolution of (scalar) attributes (resources or income in evolutionary demography or economics, position in traffic management, etc.) of a population of “mobiles” (economic agents, vehicles, etc.). The set of mobiles sharing the same attributes is regarded as an instantaneous cohort described by the number of its elements. The union of instantaneous cohorts during a mobile window between two attributes is a cohort. Given a measure defining the number of instantaneous cohorts, the accumulation of the mobile attributes on a evolving mobile window is the measure of the cohort on this temporal mobile window. Imposing accumulation constraints and departure conditions, this study is devoted to the regulation of the evolutions of the attributes which are1.viable in the sense that the accumulations constraints are satisfied at each instant;2.and, among them, optimal, in the sense that both the duration of the temporal mobile window is maximum and that the accumulation on this temporal mobile window is the largest viable one. This value is the “accumulation valuation” function. Viable and optimal evolutions under accumulation constraints are regulated by an “implicit Volterra integro-differential inclusion” built from the accumulation valuation function, solution to an Hamilton–Jacobi–Bellman partial differential equation under constraints which is constructed for this purpose.

  13. Quadcopter Path Following Control Design Using Output Feedback with Command Generator Tracker LOS Based At Square Path

    Science.gov (United States)

    Nugraha, A. T.; Agustinah, T.

    2018-01-01

    Quadcopter an unstable system, underactuated and nonlinear in quadcopter control research developments become an important focus of attention. In this study, following the path control method for position on the X and Y axis, used structure-Generator Tracker Command (CGT) is tested. Attitude control and position feedback quadcopter is compared using the optimal output. The addition of the H∞ performance optimal output feedback control is used to maintain the stability and robustness of quadcopter. Iterative numerical techniques Linear Matrix Inequality (LMI) is used to find the gain controller. The following path control problems is solved using the method of LQ regulators with output feedback. Simulations show that the control system can follow the paths that have been defined in the form of a reference signal square shape. The result of the simulation suggest that the method which used can bring the yaw angle at the expected value algorithm. Quadcopter can do automatically following path with cross track error mean X=0.5 m and Y=0.2 m.

  14. Incentive regulation of nuclear power plants by state regulators

    International Nuclear Information System (INIS)

    Martin, R.L.; Baker, K.; Olson, J.

    1991-02-01

    The Nuclear Regulatory Commission (NRC) monitors incentive programs established by state regulators in order to obtain current information and to consider the potential safety effects of the incentive programs as applied to nuclear units. The current report is an update of NUREG/CR-5509, Incentive Regulation of Nuclear Power Plants by State Public Utility Commissions, published in December 1989. The information in this report was obtained from interviews conducted with each state regulator and each utility with a minimum entitlement of 10%. The agreements, orders, and settlements from which each incentive program was implemented were reviewed as required. The interviews and supporting documentation form the basis for the individual state reports describing the structure and financial impact of each incentive program. The programs currently in effect represent the adoption of an existing nuclear performance incentive program proposal and one new program. In addition, since 1989 a number of nuclear units have been included in one existing program; while one program was discontinued and another one concluded. 6 refs., 27 tabs

  15. Mechanism of phytohormone involvement in feedback regulation of cotton leaf senescence induced by potassium deficiency.

    Science.gov (United States)

    Wang, Ye; Li, Bo; Du, Mingwei; Eneji, A Egrinya; Wang, Baomin; Duan, Liusheng; Li, Zhaohu; Tian, Xiaoli

    2012-10-01

    To elucidate the phytohormonal basis of the feedback regulation of leaf senescence induced by potassium (K) deficiency in cotton (Gossypium hirsutum L.), two cultivars contrasting in sensitivity to K deficiency were self- and reciprocally grafted hypocotyl-to-hypocotyl, using standard grafting (one scion grafted onto one rootstock), Y grafting (two scions grafted onto one rootstock), and inverted Y grafting (one scion grafted onto two rootstocks) at the seedling stage. K deficiency (0.03mM for standard and Y grafting, and 0.01mM for inverted Y grafting) increased the root abscisic acid (ABA) concentration by 1.6- to 3.1-fold and xylem ABA delivery rates by 1.8- to 4.6-fold. The K deficiency also decreased the delivery rates of xylem cytokinins [CKs; including the zeatin riboside (ZR) and isopentenyl adenosine (iPA) type] by 29-65% and leaf CK concentration by 16-57%. The leaf ABA concentration and xylem ABA deliveries were consistently greater in CCRI41 (more sensitive to K deficiency) than in SCRC22 (less sensitive to K deficiency) scions under K deficiency, and ZR- and iPA-type levels were consistently lower in the former than in the latter, irrespective of rootstock cultivar or grafting type, indicating that cotton shoot influences the levels of ABA and CKs in leaves and xylem sap. Because the scions had little influence on phytohormone levels in the roots (rootstocks) of all three types of grafts and rootstock xylem sap (collected below the graft union) of Y and inverted Y grafts, it appears that the site for basipetal feedback signal(s) involved in the regulation of xylem phytohormones is the hypocotyl of cotton seedlings. Also, the target of this feedback signal(s) is more likely to be the changes in xylem phytohormones within tissues of the hypocotyl rather than the export of phytohormones from the roots.

  16. Optimal Design of Complex Passive-Damping Systems for Vibration Control of Large Structures: An Energy-to-Peak Approach

    Directory of Open Access Journals (Sweden)

    Francisco Palacios-Quiñonero

    2014-01-01

    Full Text Available We present a new design strategy that makes it possible to synthesize decentralized output-feedback controllers by solving two successive optimization problems with linear matrix inequality (LMI constraints. In the initial LMI optimization problem, two auxiliary elements are computed: a standard state-feedback controller, which can be taken as a reference in the performance assessment, and a matrix that facilitates a proper definition of the main LMI optimization problem. Next, by solving the second optimization problem, the output-feedback controller is obtained. The proposed strategy extends recent results in static output-feedback control and can be applied to design complex passive-damping systems for vibrational control of large structures. More precisely, by taking advantages of the existing link between fully decentralized velocity-feedback controllers and passive linear dampers, advanced active feedback control strategies can be used to design complex passive-damping systems, which combine the simplicity and robustness of passive control systems with the efficiency of active feedback control. To demonstrate the effectiveness of the proposed approach, a passive-damping system for the seismic protection of a five-story building is designed with excellent results.

  17. Multi-bunch Feedback Systems

    International Nuclear Information System (INIS)

    Lonza, M; Schmickler, H

    2014-01-01

    Coupled-bunch instabilities excited by the interaction of the particle beam with its surroundings can seriously limit the performance of circular particle accelerators. These instabilities can be cured by the use of active feedback systems based on sensors capable of detecting the unwanted beam motion and actuators that apply the feedback correction to the beam. Advances in electronic technology now allow the implementation of feedback loops using programmable digital systems. Besides important advantages in terms of flexibility and reproducibility, digital systems open the way to the use of novel diagnostic tools and additional features. We first introduce coupled-bunch instabilities, analysing the equation of motion of charged particles and the different modes of oscillation of a multi-bunch beam, showing how they can be observed and measured. Different types of feedback systems will then be presented as examples of real implementations that belong to the history of multi-bunch feedback systems. The main components of a feedback system and the related issues will also be analysed. Finally, we shall focus on digital feedback systems, their characteristics, and features, as well as on how they can be concretely exploited for both the optimization of feedback performance and for beam dynamics studies

  18. On control strategies for power optimization and regulation of variable speed wind turbines; Sur les strategies de commande pour l'optimisation et la regulation de puissance des eoliennes a vitesse variable

    Energy Technology Data Exchange (ETDEWEB)

    Boukhezzar, B

    2006-02-15

    The research work is dealing with variable speed wind turbines modelling and control design, in order to achieve the objectives of maximizing the extracted energy from the wind, below the rated power area in the one hand and in the other hand regulating the electric power production, above the rated power area, while reducing mechanical transient loads. For this purpose, we have studied various control strategies from linear to nonlinear based. some of the controllers that we have developed, herein appear for the first time in the relevant domain, the remaining others are an adaptation of well know controllers to the adopted wind turbine models. as matter of fact, we have derived two wind turbine models as well as a wind speed estimator. Indeed, the estimator allows obtaining the effective wind speed which cannot be measured, since the wind profile around the rotor is variable in time and space. As results, it has been shown that single input control by means of pitch angle or generator control cannot succeed to simultaneously drive the electric power output regulation and the rotor speed reference tracking. So then, our idea is to combine nonlinear dynamic state feedback torque control and pitch linear based control which turns out to be the best strategy. In addition, the validation of the controllers performance, using a high turbulence wind speed profile, has been performed through wind turbine simulators provided by nrel (national renewable energy laboratory, golden, co), has confirmed the theoretical results and has led to quite satisfactory conclusions in terms of energy capture optimization, power regulation and disturbances strong rejection as well. (author)

  19. Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer.

    Science.gov (United States)

    Carver, Brett S; Chapinski, Caren; Wongvipat, John; Hieronymus, Haley; Chen, Yu; Chandarlapaty, Sarat; Arora, Vivek K; Le, Carl; Koutcher, Jason; Scher, Howard; Scardino, Peter T; Rosen, Neal; Sawyers, Charles L

    2011-05-17

    Prostate cancer is characterized by its dependence on androgen receptor (AR) and frequent activation of PI3K signaling. We find that AR transcriptional output is decreased in human and murine tumors with PTEN deletion and that PI3K pathway inhibition activates AR signaling by relieving feedback inhibition of HER kinases. Similarly, AR inhibition activates AKT signaling by reducing levels of the AKT phosphatase PHLPP. Thus, these two oncogenic pathways cross-regulate each other by reciprocal feedback. Inhibition of one activates the other, thereby maintaining tumor cell survival. However, combined pharmacologic inhibition of PI3K and AR signaling caused near-complete prostate cancer regressions in a Pten-deficient murine prostate cancer model and in human prostate cancer xenografts, indicating that both pathways coordinately support survival. Copyright © 2011 Elsevier Inc. All rights reserved.

  20. Optimizing engagement with Internet-based health behaviour change interventions: comparison of self-assessment with and without tailored feedback using a mixed methods approach.

    Science.gov (United States)

    Morrison, Leanne; Moss-Morris, Rona; Michie, Susan; Yardley, Lucy

    2014-11-01

    Internet-based health behaviour interventions have variable effects on health-related outcomes. Effectiveness may be improved by optimizing the design of interventions. This study examined the specific effect on engagement of providing two different design features - tailoring and self-assessment. Three versions of an Internet-delivered intervention to support the self-care of mild bowel problems were developed that provided (1) self-assessment without tailored feedback, (2) self-assessment with tailored feedback, and (3) generic information only. A qualitative study explored participants' engagement with each version of the intervention (N = 24). A larger quantitative study systematically compared participants' use of the intervention and self-reported engagement using a partial factorial design (n = 178). Findings from the qualitative study suggested that self-assessment without tailored feedback appeared to be less acceptable to participants because it was viewed as offering no personal benefit in the absence of personalized advice. In the quantitative study, self-assessment without tailored feedback was associated with greater dropout than when provided in conjunction with tailored feedback. There were significant group differences in participants' engagement with the intervention and perceptions of the intervention. Self-assessment without tailored feedback was rated as marginally less engaging and was associated with fewer positive perceptions than the generic information condition. The acceptability of self-assessment or monitoring components may be optimized by also providing tailored feedback. Without tailored feedback, these components do not appear to be any more engaging than generic information provision. Statement of contribution What is already known on this subject? Digital interventions can be effective for improving a range of health outcomes and behaviours. There is huge variation in the success of different interventions using different

  1. Southern states radiological emergency response laws and regulations

    International Nuclear Information System (INIS)

    1990-06-01

    The purpose of this report is to provide a summary of the emergency response laws and regulations in place in the various states within the southern region for use by legislators, emergency response planners, the general public and all persons concerned about the existing legal framework for emergency response. SSEB expects to periodically update the report as necessary. Radiation protection regulations without emergency response provisions are not included in the summary. The radiological emergency response laws and regulations of the Southern States Energy Compact member states are in some cases disparate. Several states have very specific laws on radiological emergency response while in others, the statutory law mentions only emergency response to ''natural disasters.'' Some states have adopted extensive regulations on the topic, others have none. For this reason, any general overview must necessarily discuss laws and regulations in general terms. State-by-state breakdowns are given for specific states

  2. Application of modern control theory to the design of optimum aircraft controllers

    Science.gov (United States)

    Power, L. J.

    1973-01-01

    The synthesis procedure presented is based on the solution of the output regulator problem of linear optimal control theory for time-invariant systems. By this technique, solution of the matrix Riccati equation leads to a constant linear feedback control law for an output regulator which will maintain a plant in a particular equilibrium condition in the presence of impulse disturbances. Two simple algorithms are presented that can be used in an automatic synthesis procedure for the design of maneuverable output regulators requiring only selected state variables for feedback. The first algorithm is for the construction of optimal feedforward control laws that can be superimposed upon a Kalman output regulator and that will drive the output of a plant to a desired constant value on command. The second algorithm is for the construction of optimal Luenberger observers that can be used to obtain feedback control laws for the output regulator requiring measurement of only part of the state vector. This algorithm constructs observers which have minimum response time under the constraint that the magnitude of the gains in the observer filter be less than some arbitrary limit.

  3. Theoretical model for ultracold molecule formation via adaptive feedback control

    International Nuclear Information System (INIS)

    Poschinger, Ulrich; Salzmann, Wenzel; Wester, Roland; Weidemueller, Matthias; Koch, Christiane P; Kosloff, Ronnie

    2006-01-01

    We theoretically investigate pump-dump photoassociation of ultracold molecules with amplitude- and phase-modulated femtosecond laser pulses. For this purpose, a perturbative model for light-matter interaction is developed and combined with a genetic algorithm for adaptive feedback control of the laser pulse shapes. The model is applied to the formation of 85 Rb 2 molecules in a magneto-optical trap. We find that optimized pulse shapes may maximize the formation of ground state molecules in a specific vibrational state at a pump-dump delay time for which unshaped pulses lead to a minimum of the formation rate. Compared to the maximum formation rate obtained for unshaped pulses at the optimum pump-dump delay, the optimized pulses lead to a significant improvement of about 40% for the target level population. Since our model yields the spectral amplitudes and phases of the optimized pulses, the results are directly applicable in pulse shaping experiments

  4. Proper Use of Feedback Leads to an Optimal Motivational Climate

    Science.gov (United States)

    Staley, Addison; Moore, E. Whitney G.

    2016-01-01

    Feedback given by coaches can have a profound effect on athletes' performance, as well as on their perception of the motivational climate. The Coaching Behaviors Assessment System classifies the feedback that coaches give during practices or games into 12 behavioral categories, which will be described in this article. Real-life scenarios will be…

  5. Use of digital control theory state space formalism for feedback at SLC

    International Nuclear Information System (INIS)

    Himel, T.; Hendrickson, L.; Rouse, F.; Shoaee, H.

    1991-05-01

    The algorithms used in the database-driven SLC fast-feedback system are based on the state space formalism of digital control theory. These are implemented as a set of matrix equations which use a Kalman filter to estimate a vector of states from a vector of measurements, and then apply a gain matrix to determine the actuator settings from the state vector. The matrices used in the calculation are derived offline using Linear Quadratic Gaussian minimization. For a given noise spectrum, this procedure minimizes the rms of the states (e.g., the position or energy of the beam). The offline program also allows simulation of the loop's response to arbitrary inputs, and calculates its frequency response. 3 refs., 3 figs

  6. On the ergodic secret message capacity of the wiretap channel with finite-rate feedback

    KAUST Repository

    Rezki, Zouheir

    2012-07-01

    We study the secret message capacity of an ergodic block fading wiretap channel with partial channel state information at the transmitter and perfect channel state information at the receivers. We consider that in addition to the statistics of the main and the eavesdropper channel state information (CSI), the sender is provided by the legitimate receiver with a q-bit feedback, at the beginning of each coherence block, through an error-free feedback channel, with capacity q bits. We establish upper and lower bounds on the secrecy capacity. We show that a positive secrecy rate is achievable even when the feedback is at the end of each coherence block and q = 1. We also show that the lower and the upper bounds coincide asymptotically as q → ∞. Finally, asymptotic analysis at high Signal-to-Noise Ratio (SNR) are presented where it is found that the capacity is bounded at high-SNR and present a simple suboptimal scalar quantizer that is capacity achieving, without the need of any numerical optimization, as q → ∞. When applied to Rayleigh fading channels, we show that, at high-SNR, a 4-bit feedback achieves 90% of the secrecy capacity when perfect main CSI is available at the transmitter. © 2012 IEEE.

  7. On the ergodic secret message capacity of the wiretap channel with finite-rate feedback

    KAUST Repository

    Rezki, Zouheir; Khisti, Ashish J.; Alouini, Mohamed-Slim

    2012-01-01

    We study the secret message capacity of an ergodic block fading wiretap channel with partial channel state information at the transmitter and perfect channel state information at the receivers. We consider that in addition to the statistics of the main and the eavesdropper channel state information (CSI), the sender is provided by the legitimate receiver with a q-bit feedback, at the beginning of each coherence block, through an error-free feedback channel, with capacity q bits. We establish upper and lower bounds on the secrecy capacity. We show that a positive secrecy rate is achievable even when the feedback is at the end of each coherence block and q = 1. We also show that the lower and the upper bounds coincide asymptotically as q → ∞. Finally, asymptotic analysis at high Signal-to-Noise Ratio (SNR) are presented where it is found that the capacity is bounded at high-SNR and present a simple suboptimal scalar quantizer that is capacity achieving, without the need of any numerical optimization, as q → ∞. When applied to Rayleigh fading channels, we show that, at high-SNR, a 4-bit feedback achieves 90% of the secrecy capacity when perfect main CSI is available at the transmitter. © 2012 IEEE.

  8. Robust chaos synchronization using input-to-state stable control

    Indian Academy of Sciences (India)

    ... be obtained by solving a convex optimization problem represented by the. LMI. Simulation studies are presented to demonstrate the effectiveness of the proposed ... one is the linear state feedback controller and the other is the nonlinear feedback controller. By the proposed control scheme, the closed-loop error system is ...

  9. GALAXY FORMATION WITH SELF-CONSISTENTLY MODELED STARS AND MASSIVE BLACK HOLES. I. FEEDBACK-REGULATED STAR FORMATION AND BLACK HOLE GROWTH

    International Nuclear Information System (INIS)

    Kim, Ji-hoon; Abel, Tom; Wise, John H.; Alvarez, Marcelo A.

    2011-01-01

    There is mounting evidence for the coevolution of galaxies and their embedded massive black holes (MBHs) in a hierarchical structure formation paradigm. To tackle the nonlinear processes of galaxy-MBH interaction, we describe a self-consistent numerical framework which incorporates both galaxies and MBHs. The high-resolution adaptive mesh refinement (AMR) code Enzo is modified to model the formation and feedback of molecular clouds at their characteristic scale of 15.2 pc and the accretion of gas onto an MBH. Two major channels of MBH feedback, radiative feedback (X-ray photons followed through full three-dimensional adaptive ray tracing) and mechanical feedback (bipolar jets resolved in high-resolution AMR), are employed. We investigate the coevolution of a 9.2 x 10 11 M sun galactic halo and its 10 5 M sun embedded MBH at redshift 3 in a cosmological ΛCDM simulation. The MBH feedback heats the surrounding interstellar medium (ISM) up to 10 6 K through photoionization and Compton heating and locally suppresses star formation in the galactic inner core. The feedback considerably changes the stellar distribution there. This new channel of feedback from a slowly growing MBH is particularly interesting because it is only locally dominant and does not require the heating of gas globally on the disk. The MBH also self-regulates its growth by keeping the surrounding ISM hot for an extended period of time.

  10. Steady state statistical correlations predict bistability in reaction motifs.

    Science.gov (United States)

    Chakravarty, Suchana; Barik, Debashis

    2017-03-28

    Various cellular decision making processes are regulated by bistable switches that take graded input signals and convert them to binary all-or-none responses. Traditionally, a bistable switch generated by a positive feedback loop is characterized either by a hysteretic signal response curve with two distinct signaling thresholds or by characterizing the bimodality of the response distribution in the bistable region. To identify the intrinsic bistability of a feedback regulated network, here we propose that bistability can be determined by correlating higher order moments and cumulants (≥2) of the joint steady state distributions of two components connected in a positive feedback loop. We performed stochastic simulations of four feedback regulated models with intrinsic bistability and we show that for a bistable switch with variation of the signal dose, the steady state variance vs. covariance adopts a signatory cusp-shaped curve. Further, we find that the (n + 1)th order cross-cumulant vs. nth order cross-cumulant adopts a closed loop structure for at least n = 3. We also propose that our method is capable of identifying systems without intrinsic bistability even though the system may show bimodality in the marginal response distribution. The proposed method can be used to analyze single cell protein data measured at steady state from experiments such as flow cytometry.

  11. Adaptive Disturbance Tracking Theory with State Estimation and State Feedback for Region II Control of Large Wind Turbines

    Science.gov (United States)

    Balas, Mark J.; Thapa Magar, Kaman S.; Frost, Susan A.

    2013-01-01

    A theory called Adaptive Disturbance Tracking Control (ADTC) is introduced and used to track the Tip Speed Ratio (TSR) of 5 MW Horizontal Axis Wind Turbine (HAWT). Since ADTC theory requires wind speed information, a wind disturbance generator model is combined with lower order plant model to estimate the wind speed as well as partial states of the wind turbine. In this paper, we present a proof of stability and convergence of ADTC theory with lower order estimator and show that the state feedback can be adaptive.

  12. State estimation and optimal long period clinical treatment of HIV seropositive patients

    Directory of Open Access Journals (Sweden)

    Juliana M. Grégio

    2009-03-01

    Full Text Available Optimal control theory provides a very interesting quantitative method that can be used to assist the decision making process in several areas of application, such as engineering, biology, economics and sociology. The main idea is to determine the values of the manipulated variables, such as drug doses, so that some cost function is minimized, subject to physical constraints. In this work, the cost function reflects the number of CD4+T cells, viral particles and the drug doses. It is worth noticing that high drug doses are related to more intense side-effects, apart from the impact on the actual cost of the treatment. In a previous paper by the authors, the LQR - Linear Quadratic Regulator approach was proposed for the computation of long period maintenance doses for the drugs, which turns out to be of state feedback form. However, it is not practical to determine all the components of the state vector, due to the fact that infected and uninfected CD4+T cells are not microscopically distinguishable. In order to overcome this difficulty, this work proposes the use of Extended Kalman Filter to estimate the state, even though, because of the nonlinear nature of the involved state equations, the separation principle may not be valid. Extensive simulations were then carried out to investigate numerically if the control strategy consisting of the feedback of estimated states yielded satisfactory clinical results.A teoria de controle ótimo apresenta um método quantitativo muito interessante que pode ajudar no processo de tomada de decisão em algumas áreas de aplicação, tais como engenharia, biologia, economia e sociologia. A principal idéia é determinar os valores das variáveis controladas, tais como doses de medicamentos, onde alguma função-custo é minimizada, sujeito às restrições físicas. Neste trabalho, a função-custo reflete o número de células CD4+T, partículas virais e doses de medicamentos. É fato que altas dosagens de

  13. Adaptive disengagement buffers self-esteem from negative social feedback.

    Science.gov (United States)

    Leitner, Jordan B; Hehman, Eric; Deegan, Matthew P; Jones, James M

    2014-11-01

    The degree to which self-esteem hinges on feedback in a domain is known as a contingency of self-worth, or engagement. Although previous research has conceptualized engagement as stable, it would be advantageous for individuals to dynamically regulate engagement. The current research examined whether the tendency to disengage from negative feedback accounts for variability in self-esteem. We created the Adaptive Disengagement Scale (ADS) to capture individual differences in the tendency to disengage self-esteem from negative outcomes. Results demonstrated that the ADS is reliable and valid (Studies 1 and 2). Furthermore, in response to negative social feedback, higher scores on the ADS predicted greater state self-esteem (Study 3), and this relationship was mediated by disengagement (Study 4). These findings demonstrate that adaptive disengagement protects self-esteem from negative outcomes and that the ADS is a valid measure of individual differences in the implementation of this process. © 2014 by the Society for Personality and Social Psychology, Inc.

  14. A Direct Algorithm for Pole Placement by State-derivative Feedback for Single-input Linear Systems

    Directory of Open Access Journals (Sweden)

    Taha H. S. Abdelaziz

    2003-01-01

    Full Text Available This paper deals with the direct solution of the pole placement problem for single-input linear systems using state-derivative feedback. This pole placement problem is always solvable for any controllable systems if all eigenvalues of the original system are nonzero. Then any arbitrary closed-loop poles can be placed in order to achieve the desired system performance. The solving procedure results in a formula similar to the Ackermann formula. Its derivation is based on the transformation of a linear single-input system into Frobenius canonical form by a special coordinate transformation, then solving the pole placement problem by state derivative feedback. Finally the solution is extended also for single-input time-varying control systems. The simulation results are included to show the effectiveness of the proposed approach.

  15. Feedback stabilization initiative

    International Nuclear Information System (INIS)

    1997-06-01

    Much progress has been made in attaining high confinement regimes in magnetic confinement devices. These operating modes tend to be transient, however, due to the onset of MHD instabilities, and their stabilization is critical for improved performance at steady state. This report describes the Feedback Stabilization Initiative (FSI), a broad-based, multi-institutional effort to develop and implement methods for raising the achievable plasma betas through active MHD feedback stabilization. A key element in this proposed effort is the Feedback Stabilization Experiment (FSX), a medium-sized, national facility that would be specifically dedicated to demonstrating beta improvement in reactor relevant plasmas by using a variety of MHD feedback stabilization schemes

  16. Feedback stabilization initiative

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-06-01

    Much progress has been made in attaining high confinement regimes in magnetic confinement devices. These operating modes tend to be transient, however, due to the onset of MHD instabilities, and their stabilization is critical for improved performance at steady state. This report describes the Feedback Stabilization Initiative (FSI), a broad-based, multi-institutional effort to develop and implement methods for raising the achievable plasma betas through active MHD feedback stabilization. A key element in this proposed effort is the Feedback Stabilization Experiment (FSX), a medium-sized, national facility that would be specifically dedicated to demonstrating beta improvement in reactor relevant plasmas by using a variety of MHD feedback stabilization schemes.

  17. Systemic Model for Optimal Regulation in Public Service

    Directory of Open Access Journals (Sweden)

    Lucica Matei

    2006-05-01

    Full Text Available The current paper inscribes within those approaching the issue of public services from the interdisciplinary perspective. Public service development and imposing standards of efficiency and effectiveness, as well as for citizens’ satisfaction bring in front line the systemic modelling and establishing optimal policies for organisation and functioning of public services. The issue under discussion imposes an interface with powerful determinations of social nature. Consequently, the most adequate modelling might be that with a probabilistic and statistic nature. The fundamental idea of this paper, that obviously can be broadly developed, starts with assimilating the way of organisation and functioning of a public service with a waiting thread, to which some hypotheses are associated concerning the order of provision, performance measurement through costs or waiting time in the system etc. We emphasise the openness and dynamics of the public service system, as well as modelling by turning into account the statistic knowledge and researches, and we do not make detailed remarks on the cybernetic characteristics of this system. The optimal adjustment is achieved through analysis on the feedback and its comparison with the current standards or good practices.

  18. Southern states radiological emergency response laws and regulations

    International Nuclear Information System (INIS)

    1989-02-01

    The radiological emergency response laws and regulations of the Southern States Energy Compact member states are in some cases disparate. Several states have very specific laws on radiological emergency response while in others, the statutory law mentions only emergency response to ''natural disasters.'' Some states have adopted extensive regulations on the topic; others have none. For this reason, any general overview must necessarily discuss laws and regulations in general terms

  19. Finite-time stabilization of uncertain nonholonomic systems in feedforward-like form by output feedback.

    Science.gov (United States)

    Gao, Fangzheng; Wu, Yuqiang; Zhang, Zhongcai

    2015-11-01

    This paper investigates the problem of finite-time stabilization by output feedback for a class of nonholonomic systems in chained form with uncertainties. Comparing with the existing relevant literature, a distinguishing feature of the systems under investigation is that the x-subsystem is a feedforward-like rather than feedback-like system. This renders the existing control methods inapplicable to the control problems of the systems. A constructive design procedure for output feedback control is given. The designed controller renders that the states of closed-loop system are regulated to zero in a finite time. Two simulation examples are provided to illustrate the effectiveness of the proposed approach. Copyright © 2015 ISA. Published by Elsevier Ltd. All rights reserved.

  20. Feedback systems for linear colliders

    CERN Document Server

    Hendrickson, L; Himel, Thomas M; Minty, Michiko G; Phinney, N; Raimondi, Pantaleo; Raubenheimer, T O; Shoaee, H; Tenenbaum, P G

    1999-01-01

    Feedback systems are essential for stable operation of a linear collider, providing a cost-effective method for relaxing tight tolerances. In the Stanford Linear Collider (SLC), feedback controls beam parameters such as trajectory, energy, and intensity throughout the accelerator. A novel dithering optimization system which adjusts final focus parameters to maximize luminosity contributed to achieving record performance in the 1997-98 run. Performance limitations of the steering feedback have been investigated, and improvements have been made. For the Next Linear Collider (NLC), extensive feedback systems are planned as an intregal part of the design. Feedback requiremetns for JLC (the Japanese Linear Collider) are essentially identical to NLC; some of the TESLA requirements are similar but there are significant differences. For NLC, algorithms which incorporate improvements upon the SLC implementation are being prototyped. Specialized systems for the damping rings, rf and interaction point will operate at hi...

  1. Small G proteins Rac1 and Ras regulate serine/threonine protein phosphatase 5 (PP5)·extracellular signal-regulated kinase (ERK) complexes involved in the feedback regulation of Raf1.

    Science.gov (United States)

    Mazalouskas, Matthew D; Godoy-Ruiz, Raquel; Weber, David J; Zimmer, Danna B; Honkanen, Richard E; Wadzinski, Brian E

    2014-02-14

    Serine/threonine protein phosphatase 5 (PP5, PPP5C) is known to interact with the chaperonin heat shock protein 90 (HSP90) and is involved in the regulation of multiple cellular signaling cascades that control diverse cellular processes, such as cell growth, differentiation, proliferation, motility, and apoptosis. Here, we identify PP5 in stable complexes with extracellular signal-regulated kinases (ERKs). Studies using mutant proteins reveal that the formation of PP5·ERK1 and PP5·ERK2 complexes partially depends on HSP90 binding to PP5 but does not require PP5 or ERK1/2 activity. However, PP5 and ERK activity regulates the phosphorylation state of Raf1 kinase, an upstream activator of ERK signaling. Whereas expression of constitutively active Rac1 promotes the assembly of PP5·ERK1/2 complexes, acute activation of ERK1/2 fails to influence the phosphatase-kinase interaction. Introduction of oncogenic HRas (HRas(V12)) has no effect on PP5-ERK1 binding but selectively decreases the interaction of PP5 with ERK2, in a manner that is independent of PP5 and MAPK/ERK kinase (MEK) activity, yet paradoxically requires ERK2 activity. Additional studies conducted with oncogenic variants of KRas4B reveal that KRas(L61), but not KRas(V12), also decreases the PP5-ERK2 interaction. The expression of wild type HRas or KRas proteins fails to reduce PP5-ERK2 binding, indicating that the effect is specific to HRas(V12) and KRas(L61) gain-of-function mutations. These findings reveal a novel, differential responsiveness of PP5-ERK1 and PP5-ERK2 interactions to select oncogenic Ras variants and also support a role for PP5·ERK complexes in regulating the feedback phosphorylation of PP5-associated Raf1.

  2. Deceptive Business Practices: State Regulations.

    Science.gov (United States)

    Rohrer, Daniel Morgan

    Although much has been done at the federal level to control deceptive advertising practices, many states have no criminal laws designed to regulate advertising, and several states recently repealed such laws. This paper examines states' efforts to balance the advertiser's freedom of speech with the consumer's need for information about products by…

  3. Theoretical model for ultracold molecule formation via adaptive feedback control

    OpenAIRE

    Poschinger, Ulrich; Salzmann, Wenzel; Wester, Roland; Weidemueller, Matthias; Koch, Christiane P.; Kosloff, Ronnie

    2006-01-01

    We investigate pump-dump photoassociation of ultracold molecules with amplitude- and phase-modulated femtosecond laser pulses. For this purpose a perturbative model for the light-matter interaction is developed and combined with a genetic algorithm for adaptive feedback control of the laser pulse shapes. The model is applied to the formation of 85Rb2 molecules in a magneto-optical trap. We find for optimized pulse shapes an improvement for the formation of ground state molecules by more than ...

  4. Dynamic, nonlinear feedback regulation of slow pacemaking by A-type potassium current in ventral tegmental area neurons.

    Science.gov (United States)

    Khaliq, Zayd M; Bean, Bruce P

    2008-10-22

    We analyzed ionic currents that regulate pacemaking in dopaminergic neurons of the mouse ventral tegmental area by comparing voltage trajectories during spontaneous firing with ramp-evoked currents in voltage clamp. Most recordings were made in brain slice, with key experiments repeated using acutely dissociated neurons, which gave identical results. During spontaneous firing, net ionic current flowing between spikes was calculated from the time derivative of voltage multiplied by cell capacitance, signal-averaged over many firing cycles to enhance resolution. Net inward interspike current had a distinctive nonmonotonic shape, reaching a minimum (generally current that peaked near -55 mV. This current was undetectable with 5 mV/s ramps and increased steeply with depolarization rate over the range (10-50 mV/s) typical of natural pacemaking. Ramp-evoked subthreshold current was resistant to alpha-dendrotoxin, paxilline, apamin, and tetraethylammonium but sensitive to 4-aminopyridine and 0.5 mM Ba2+, consistent with A-type potassium current (I(A)). Same-cell comparison of currents elicited by various ramp speeds with natural spontaneous depolarization showed how the steep dependence of I(A) on depolarization rate results in small net inward currents during pacemaking. These results reveal a mechanism in which subthreshold I(A) is near zero at steady state, but is engaged at depolarization rates >10 mV/s to act as a powerful, supralinear feedback element. This feedback mechanism explains how net ionic current can be constrained to <1-2 pA but reliably inward, thus enabling slow, regular firing.

  5. Compiler Feedback using Continuous Dynamic Compilation during Development

    DEFF Research Database (Denmark)

    Jensen, Nicklas Bo; Karlsson, Sven; Probst, Christian W.

    2014-01-01

    to optimization. This tool can help programmers understand what the optimizing compiler has done and suggest automatic source code changes in cases where the compiler refrains from optimizing. We have integrated our tool into an integrated development environment, interactively giving feedback as part...

  6. Improved Sensitivity Relations in State Constrained Optimal Control

    International Nuclear Information System (INIS)

    Bettiol, Piernicola; Frankowska, Hélène; Vinter, Richard B.

    2015-01-01

    Sensitivity relations in optimal control provide an interpretation of the costate trajectory and the Hamiltonian, evaluated along an optimal trajectory, in terms of gradients of the value function. While sensitivity relations are a straightforward consequence of standard transversality conditions for state constraint free optimal control problems formulated in terms of control-dependent differential equations with smooth data, their verification for problems with either pathwise state constraints, nonsmooth data, or for problems where the dynamic constraint takes the form of a differential inclusion, requires careful analysis. In this paper we establish validity of both ‘full’ and ‘partial’ sensitivity relations for an adjoint state of the maximum principle, for optimal control problems with pathwise state constraints, where the underlying control system is described by a differential inclusion. The partial sensitivity relation interprets the costate in terms of partial Clarke subgradients of the value function with respect to the state variable, while the full sensitivity relation interprets the couple, comprising the costate and Hamiltonian, as the Clarke subgradient of the value function with respect to both time and state variables. These relations are distinct because, for nonsmooth data, the partial Clarke subdifferential does not coincide with the projection of the (full) Clarke subdifferential on the relevant coordinate space. We show for the first time (even for problems without state constraints) that a costate trajectory can be chosen to satisfy the partial and full sensitivity relations simultaneously. The partial sensitivity relation in this paper is new for state constraint problems, while the full sensitivity relation improves on earlier results in the literature (for optimal control problems formulated in terms of Lipschitz continuous multifunctions), because a less restrictive inward pointing hypothesis is invoked in the proof, and because

  7. Design of Optimal Hybrid Position/Force Controller for a Robot Manipulator Using Neural Networks

    Directory of Open Access Journals (Sweden)

    Vikas Panwar

    2007-01-01

    Full Text Available The application of quadratic optimization and sliding-mode approach is considered for hybrid position and force control of a robot manipulator. The dynamic model of the manipulator is transformed into a state-space model to contain two sets of state variables, where one describes the constrained motion and the other describes the unconstrained motion. The optimal feedback control law is derived solving matrix differential Riccati equation, which is obtained using Hamilton Jacobi Bellman optimization. The optimal feedback control law is shown to be globally exponentially stable using Lyapunov function approach. The dynamic model uncertainties are compensated with a feedforward neural network. The neural network requires no preliminary offline training and is trained with online weight tuning algorithms that guarantee small errors and bounded control signals. The application of the derived control law is demonstrated through simulation with a 4-DOF robot manipulator to track an elliptical planar constrained surface while applying the desired force on the surface.

  8. On the Secrecy Capacity of the Multiple-Antenna Wiretap Channel with Limited CSI Feedback

    KAUST Repository

    Hyadi, Amal; Rezki, Zouheir; Alouini, Mohamed-Slim

    2015-01-01

    We study the ergodic secrecy capacity of a block fading wiretap channel when there are multiple antennas at the transmitter, the legitimate receiver and the eavesdropper. We consider that the receivers are aware of their respective channel matrices while the transmitter is only provided by a B-bits feedback of the main channel state information. The feedback bits are sent by the legitimate receiver, at the beginning of each fading block, over an error free public link with limited capacity. Assuming an average transmit power constraint, we provide an upper and a lower bounds on the ergodic secrecy capacity. Then, we present a framework to design the optimal codebooks for feedback and transmission. In addition, we show that the proposed lower and upper bounds coincide asymptotically as the capacity of the feedback link becomes large; hence, fully characterizing the secrecy capacity in this case.

  9. On the Secrecy Capacity of the Multiple-Antenna Wiretap Channel with Limited CSI Feedback

    KAUST Repository

    Hyadi, Amal

    2015-12-01

    We study the ergodic secrecy capacity of a block fading wiretap channel when there are multiple antennas at the transmitter, the legitimate receiver and the eavesdropper. We consider that the receivers are aware of their respective channel matrices while the transmitter is only provided by a B-bits feedback of the main channel state information. The feedback bits are sent by the legitimate receiver, at the beginning of each fading block, over an error free public link with limited capacity. Assuming an average transmit power constraint, we provide an upper and a lower bounds on the ergodic secrecy capacity. Then, we present a framework to design the optimal codebooks for feedback and transmission. In addition, we show that the proposed lower and upper bounds coincide asymptotically as the capacity of the feedback link becomes large; hence, fully characterizing the secrecy capacity in this case.

  10. Galaxy Formation with Self-Consistently Modeled Stars and Massive Black Holes. I: Feedback-Regulated Star Formation and Black Hole Growth

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ji-hoon; Wise, John H.; /KIPAC, Menlo Park /Stanford U., Phys. Dept. /Princeton U., Astrophys. Sci. Dept.; Alvarez, Marcelo A.; /Canadian Inst. Theor. Astrophys.; Abel, Tom; /KIPAC, Menlo Park /Stanford U., Phys. Dept.

    2011-11-04

    There is mounting evidence for the coevolution of galaxies and their embedded massive black holes (MBHs) in a hierarchical structure formation paradigm. To tackle the nonlinear processes of galaxy-MBH interaction, we describe a self-consistent numerical framework which incorporates both galaxies and MBHs. The high-resolution adaptive mesh refinement (AMR) code Enzo is modified to model the formation and feedback of molecular clouds at their characteristic scale of 15.2 pc and the accretion of gas onto an MBH. Two major channels of MBH feedback, radiative feedback (X-ray photons followed through full three-dimensional adaptive ray tracing) and mechanical feedback (bipolar jets resolved in high-resolution AMR), are employed. We investigate the coevolution of a 9.2 x 10{sup 11} M {circle_dot} galactic halo and its 10{sup 5} {circle_dot} M embedded MBH at redshift 3 in a cosmological CDM simulation. The MBH feedback heats the surrounding interstellar medium (ISM) up to 10{sup 6} K through photoionization and Compton heating and locally suppresses star formation in the galactic inner core. The feedback considerably changes the stellar distribution there. This new channel of feedback from a slowly growing MBH is particularly interesting because it is only locally dominant and does not require the heating of gas globally on the disk. The MBH also self-regulates its growth by keeping the surrounding ISM hot for an extended period of time.

  11. Assessing feedback in a mobile videogame

    Science.gov (United States)

    Player feedback is an important part of serious games, although there is no consensus regarding its delivery or optimal content. "Mommio" is a serious game designed to help mothers motivate their preschoolers to eat vegetables. The purpose of this study was to assess optimal format and content of pl...

  12. Can performance feedback during instruction boost knowledge acquisition? Contrasting criterion-based and social comparison feedback

    NARCIS (Netherlands)

    Kolloffel, Bas Jan; de Jong, Anthonius J.M.

    2016-01-01

    Feedback indicating how well students are performing during a learning task can be very stimulating. In this study with a pre- and post-test design, the effects of two types of performance feedback on learning results were compared: feedback during a learning task was either stated in terms of how

  13. Optimal Control for a Class of Chaotic Systems

    Directory of Open Access Journals (Sweden)

    Jianxiong Zhang

    2012-01-01

    Full Text Available This paper proposes the optimal control methods for a class of chaotic systems via state feedback. By converting the chaotic systems to the form of uncertain piecewise linear systems, we can obtain the optimal controller minimizing the upper bound on cost function by virtue of the robust optimal control method of piecewise linear systems, which is cast as an optimization problem under constraints of bilinear matrix inequalities (BMIs. In addition, the lower bound on cost function can be achieved by solving a semidefinite programming (SDP. Finally, numerical examples are given to illustrate the results.

  14. Differences in context and feedback result in different trajectories and adaptation strategies in reaching.

    Directory of Open Access Journals (Sweden)

    Fritzie Arce

    Full Text Available Computational models of motor control have often explained the straightness of horizontal planar reaching movements as a consequence of optimal control. Departure from rectilinearity is thus regarded as sub-optimal. Here we examine if subjects may instead select to make curved trajectories following adaptation to force fields and visuomotor rotations. Separate subjects adapted to force fields with or without visual feedback of their hand trajectory and were retested after 24 hours. Following adaptation, comparable accuracies were achieved in two ways: with visual feedback, adapted trajectories in force fields were straight whereas without it, they remained curved. The results suggest that trajectory shape is not always straight, but is also influenced by the calibration of available feedback signals for the state estimation required by the task. In a follow-up experiment, where additional subjects learned a visuomotor rotation immediately after force field, the trajectories learned in force fields (straight or curved were transferred when directions of the perturbations were similar but not when directions were opposing. This demonstrates a strong bias by prior experience to keep using a recently acquired control policy that continues to produce successful performance inspite of differences in tasks and feedback conditions. On relearning of force fields on the second day, facilitation by intervening visuomotor rotations occurred only when required motor adjustments and calibration of feedback signals were similar in both tasks. These results suggest that both the available feedback signals and prior history of learning influence the choice and maintenance of control policy during adaptations.

  15. Effect of overall feedback inhibition in unbranched biosynthetic pathways.

    Science.gov (United States)

    Alves, R; Savageau, M A

    2000-11-01

    We have determined the effects of control by overall feedback inhibition on the systemic behavior of unbranched metabolic pathways with an arbitrary pattern of other feedback inhibitions by using a recently developed numerical generalization of Mathematically Controlled Comparisons, a method for comparing the function of alternative molecular designs. This method allows the rigorous determination of the changes in systemic properties that can be exclusively attributed to overall feedback inhibition. Analytical results show that the unbranched pathway can achieve the same steady-state flux, concentrations, and logarithmic gains with respect to changes in substrate, with or without overall feedback inhibition. The analytical approach also shows that control by overall feedback inhibition amplifies the regulation of flux by the demand for end product while attenuating the sensitivity of the concentrations to the same demand. This approach does not provide a clear answer regarding the effect of overall feedback inhibition on the robustness, stability, and transient time of the pathway. However, the generalized numerical method we have used does clarify the answers to these questions. On average, an unbranched pathway with control by overall feedback inhibition is less sensitive to perturbations in the values of the parameters that define the system. The difference in robustness can range from a few percent to fifty percent or more, depending on the length of the pathway and on the metabolite one considers. On average, overall feedback inhibition decreases the stability margins by a minimal amount (typically less than 5%). Finally, and again on average, stable systems with overall feedback inhibition respond faster to fluctuations in the metabolite concentrations. Taken together, these results show that control by overall feedback inhibition confers several functional advantages upon unbranched pathways. These advantages provide a rationale for the prevalence of this

  16. Optimal control of transitions between nonequilibrium steady states.

    Directory of Open Access Journals (Sweden)

    Patrick R Zulkowski

    Full Text Available Biological systems fundamentally exist out of equilibrium in order to preserve organized structures and processes. Many changing cellular conditions can be represented as transitions between nonequilibrium steady states, and organisms have an interest in optimizing such transitions. Using the Hatano-Sasa Y-value, we extend a recently developed geometrical framework for determining optimal protocols so that it can be applied to systems driven from nonequilibrium steady states. We calculate and numerically verify optimal protocols for a colloidal particle dragged through solution by a translating optical trap with two controllable parameters. We offer experimental predictions, specifically that optimal protocols are significantly less costly than naive ones. Optimal protocols similar to these may ultimately point to design principles for biological energy transduction systems and guide the design of artificial molecular machines.

  17. Enhancement of vegetation-rainfall feedbacks on the Australian summer monsoon by the Madden-Julian Oscillation

    Science.gov (United States)

    Notaro, Michael

    2018-01-01

    A regional climate modeling analysis of the Australian monsoon system reveals a substantial modulation of vegetation-rainfall feedbacks by the Madden Julian Oscillation (MJO), both of which operate at similar sub-seasonal time scales, as evidence that the intensity of land-atmosphere interactions is sensitive to the background atmospheric state. Based on ensemble experiments with imposed modification of northern Australian leaf area index (LAI), the atmospheric responses to LAI anomalies are composited for negative and positive modes of the propagating MJO. In the regional climate model (RCM), northern Australian vegetation feedbacks are characterized by evapotranspiration (ET)-driven rainfall responses, with the moisture feedback mechanism dominating over albedo and roughness feedback mechanisms. During November-April, both Tropical Rainfall Measuring Mission and RCM data reveal MJO's pronounced influence on rainfall patterns across northern Australia, tropical Indian Ocean, Timor Sea, Arafura Sea, and Gulf of Carpentaria, with the MJO dominating over vegetation feedbacks in terms of regulating monsoon rainfall variability. Convectively-active MJO phases support an enhancement of positive vegetation feedbacks on monsoon rainfall. While the MJO imposes minimal regulation of ET responses to LAI anomalies, the vegetation feedback-induced responses in precipitable water, cloud water, and rainfall are greatly enhanced during convectively-active MJO phases over northern Australia, which are characterized by intense low-level convergence and efficient precipitable water conversion. The sub-seasonal response of vegetation-rainfall feedback intensity to the MJO is complex, with significant enhancement of rainfall responses to LAI anomalies in February during convectively-active MJO phases compared to minimal modulation by the MJO during prior and subsequent calendar months.

  18. Feedback Systems for Linear Colliders

    International Nuclear Information System (INIS)

    1999-01-01

    Feedback systems are essential for stable operation of a linear collider, providing a cost-effective method for relaxing tight tolerances. In the Stanford Linear Collider (SLC), feedback controls beam parameters such as trajectory, energy, and intensity throughout the accelerator. A novel dithering optimization system which adjusts final focus parameters to maximize luminosity contributed to achieving record performance in the 1997-98 run. Performance limitations of the steering feedback have been investigated, and improvements have been made. For the Next Linear Collider (NLC), extensive feedback systems are planned as an integral part of the design. Feedback requirements for JLC (the Japanese Linear Collider) are essentially identical to NLC; some of the TESLA requirements are similar but there are significant differences. For NLC, algorithms which incorporate improvements upon the SLC implementation are being prototyped. Specialized systems for the damping rings, rf and interaction point will operate at high bandwidth and fast response. To correct for the motion of individual bunches within a train, both feedforward and feedback systems are planned. SLC experience has shown that feedback systems are an invaluable operational tool for decoupling systems, allowing precision tuning, and providing pulse-to-pulse diagnostics. Feedback systems for the NLC will incorporate the key SLC features and the benefits of advancing technologies

  19. Kiloparsec-scale Simulations of Star Formation in Disk Galaxies. IV. Regulation of Galactic Star Formation Rates by Stellar Feedback

    International Nuclear Information System (INIS)

    Butler, Michael J.; Tan, Jonathan C.; Teyssier, Romain; Nickerson, Sarah; Rosdahl, Joakim; Van Loo, Sven

    2017-01-01

    Star formation from the interstellar medium of galactic disks is a basic process controlling the evolution of galaxies. Understanding the star formation rate (SFR) in a local patch of a disk with a given gas mass is thus an important challenge for theoretical models. Here we simulate a kiloparsec region of a disk, following the evolution of self-gravitating molecular clouds down to subparsec scales, as they form stars that then inject feedback energy by dissociating and ionizing UV photons and supernova explosions. We assess the relative importance of each feedback mechanism. We find that H 2 -dissociating feedback results in the largest absolute reduction in star formation compared to the run with no feedback. Subsequently adding photoionization feedback produces a more modest reduction. Our fiducial models that combine all three feedback mechanisms yield, without fine-tuning, SFRs that are in excellent agreement with observations, with H 2 -dissociating photons playing a crucial role. Models that only include supernova feedback—a common method in galaxy evolution simulations—settle to similar SFRs, but with very different temperatures and chemical states of the gas, and with very different spatial distributions of young stars.

  20. Kiloparsec-scale Simulations of Star Formation in Disk Galaxies. IV. Regulation of Galactic Star Formation Rates by Stellar Feedback

    Energy Technology Data Exchange (ETDEWEB)

    Butler, Michael J. [Max Planck Institute for Astronomy, Königstuhl 17, D-69117 Heidelberg (Germany); Tan, Jonathan C. [Departments of Astronomy and Physics, University of Florida, Gainesville, FL 32611 (United States); Teyssier, Romain; Nickerson, Sarah [Institute for Computational Science, University of Zurich, 8049 Zurich (Switzerland); Rosdahl, Joakim [Leiden Observatory, Leiden University, P.O. Box 9513, NL-2300 RA Leiden (Netherlands); Van Loo, Sven [School of Physics and Astronomy, University of Leeds, Leeds LS2 9JT (United Kingdom)

    2017-06-01

    Star formation from the interstellar medium of galactic disks is a basic process controlling the evolution of galaxies. Understanding the star formation rate (SFR) in a local patch of a disk with a given gas mass is thus an important challenge for theoretical models. Here we simulate a kiloparsec region of a disk, following the evolution of self-gravitating molecular clouds down to subparsec scales, as they form stars that then inject feedback energy by dissociating and ionizing UV photons and supernova explosions. We assess the relative importance of each feedback mechanism. We find that H{sub 2}-dissociating feedback results in the largest absolute reduction in star formation compared to the run with no feedback. Subsequently adding photoionization feedback produces a more modest reduction. Our fiducial models that combine all three feedback mechanisms yield, without fine-tuning, SFRs that are in excellent agreement with observations, with H{sub 2}-dissociating photons playing a crucial role. Models that only include supernova feedback—a common method in galaxy evolution simulations—settle to similar SFRs, but with very different temperatures and chemical states of the gas, and with very different spatial distributions of young stars.

  1. Optimized tokamak power exhaust with double radiative feedback in ASDEX Upgrade

    Science.gov (United States)

    Kallenbach, A.; Bernert, M.; Eich, T.; Fuchs, J. C.; Giannone, L.; Herrmann, A.; Schweinzer, J.; Treutterer, W.; the ASDEX Upgrade Team

    2012-12-01

    A double radiative feedback technique has been developed on the ASDEX Upgrade tokamak for optimization of power exhaust with a standard vertical target divertor. The main chamber radiation is measured in real time by a subset of three foil bolometer channels and controlled by argon injection in the outer midplane. The target heat flux is in addition controlled by nitrogen injection in the divertor private flux region using either a thermoelectric sensor or the scaled divertor radiation obtained by a bolometer channel in the outer divertor. No negative interference of the two radiation controllers has been observed so far. The combination of main chamber and divertor radiative cooling extends the operational space of a standard divertor configuration towards high values of P/R. Pheat/R = 14 MW m-1 has been achieved so far with nitrogen seeding alone as well as with combined N + Ar injection, with the time-averaged divertor peak heat flux below 5 MW m-2. Good plasma performance can be maintained under these conditions, namely H98(y,2) = 1 and βN = 3.

  2. Adaptive landing gear concept—feedback control validation

    Science.gov (United States)

    Mikulowski, Grzegorz M.; Holnicki-Szulc, Jan

    2007-12-01

    The objective of this paper is to present an integrated feedback control concept for adaptive landing gears (ALG) and its experimental validation. Aeroplanes are subjected to high dynamic loads as a result of the impact during each landing. Classical landing gears, which are in common use, are designed in accordance with official regulations in a way that ensures the optimal energy dissipation for the critical (maximum) sink speed. The regulations were formulated in order to ensure the functional capability of the landing gears during an emergency landing. However, the landing gears, whose characteristics are optimized for these critical conditions, do not perform well under normal impact conditions. For that situation it is reasonable to introduce a system that would adapt the characteristics of the landing gears according to the sink speed of landing. The considered system assumes adaptation of the damping force generated by the landing gear, which would perform optimally in an emergency situation and would adapt itself for regular landings as well. This research covers the formulation and design of the control algorithms for an adaptive landing gear based on MR fluid, implementation of the algorithms on an FPGA platform and experimental verification on a lab-scale landing gear device. The main challenge of the research was to develop a control methodology that could operate effectively within 50 ms, which is assumed to be the total duration of the phenomenon. The control algorithm proposed in this research was able to control the energy dissipation process on the experimental stand.

  3. Evaluation of State-of-the-Art Acoustic Feedback Cancellation Systems for Hearing Aids

    DEFF Research Database (Denmark)

    Guo, Meng; Jensen, Søren Holdt; Jensen, Jesper

    2013-01-01

    This research evaluates four state-of-the-art acoustic feedback cancellation systems in hearing aids in terms of the cancellation performance, sound quality degradation, and computational complexity. The authors compared a traditional full-band system to a system with a prediction error method...... in a full band, a subband system, a subband system with frequency shifting, and a recently proposed subband system with a novel probe noise deployment. All systems outperformed the traditional full-band system in cancellation performance, especially the subband system with probe noise is most effective...... for cancellation. However, in all cases there was a trade-off between performance and computational cost. With a 3-times increase in computation load, the probe noise based cancellation system can be realized that functions even in the most challenging feedback situation....

  4. Optimal Operation and Dispatch of Voltage Regulation Devices Considering High Penetrations of Distributed Photovoltaic Generation

    Energy Technology Data Exchange (ETDEWEB)

    Mather, Barry A [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Hodge, Brian S [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Cho, Gyu-Jung [Sungkyunkwan University; Oh, Yun-Sik [Sungkyunkwan University; Kim, Min-Sung [Sungkyunkwan University; Kim, Ji-Soo [Sungkyunkwan University; Kim, Chul-Hwan [Sungkyunkwan University

    2017-06-29

    Voltage regulation devices have been traditionally installed and utilized to support distribution voltages. Installations of distributed energy resources (DERs) in distribution systems are rapidly increasing, and many of these generation resources have variable and uncertain power output. These generators can significantly change the voltage profile for a feeder; therefore, in the distribution system planning stage of the optimal operation and dispatch of voltage regulation devices, possible high penetrations of DERs should be considered. In this paper, we model the IEEE 34-bus test feeder, including all essential equipment. An optimization method is adopted to determine the optimal siting and operation of the voltage regulation devices in the presence of distributed solar power generation. Finally, we verify the optimal configuration of the entire system through the optimization and simulation results.

  5. State feedback integral control for a rotary direct drive servo valve using a Lyapunov function approach.

    Science.gov (United States)

    Yu, Jue; Zhuang, Jian; Yu, Dehong

    2015-01-01

    This paper concerns a state feedback integral control using a Lyapunov function approach for a rotary direct drive servo valve (RDDV) while considering parameter uncertainties. Modeling of this RDDV servovalve reveals that its mechanical performance is deeply influenced by friction torques and flow torques; however, these torques are uncertain and mutable due to the nature of fluid flow. To eliminate load resistance and to achieve satisfactory position responses, this paper develops a state feedback control that integrates an integral action and a Lyapunov function. The integral action is introduced to address the nonzero steady-state error; in particular, the Lyapunov function is employed to improve control robustness by adjusting the varying parameters within their value ranges. This new controller also has the advantages of simple structure and ease of implementation. Simulation and experimental results demonstrate that the proposed controller can achieve higher control accuracy and stronger robustness. Copyright © 2014 ISA. Published by Elsevier Ltd. All rights reserved.

  6. Can Performance Feedback during Instruction Boost Knowledge Acquisition? Contrasting Criterion-Based and Social Comparison Feedback

    Science.gov (United States)

    Kollöffel, Bas; de Jong, Ton

    2016-01-01

    Feedback indicating how well students are performing during a learning task can be very stimulating. In this study with a pre- and post-test design, the effects of two types of performance feedback on learning results were compared: feedback during a learning task was either stated in terms of how well the students were performing relative to…

  7. Stability and oscillation of two coupled Duffing equations with time delay state feedback

    International Nuclear Information System (INIS)

    El-Bassiouny, A F

    2006-01-01

    This paper presents an analytical study of the simultaneous principal parametric resonances of two coupled Duffing equations with time delay state feedback. The concept of an equivalent damping related to the delay feedback is proposed and the appropriate choice of the feedback gains and the time delay is discussed from the viewpoint of vibration control. The method of multiple scales is used to determine a set of ordinary differential equations governing the modulation of the amplitudes and phases of the two modes. The first order approximation of the resonances are derived and the effect of time delay on the resonances is investigated. The fixed points correspond to a periodic motion for the starting system and we show the frequency-response curves. We analyse the effect of time delay and the other different parameters on these oscillations. The stability of the fixed points is examined by using the variational method. Numerical solutions are carried out and graphical representations of the results are presented and discussed. Increasing in the time delay τ given decreasing and increasing in the regions of definition and stability respectively and the first mode has decreased magnitudes. The multivalued solutions disappear when decreasing the coefficients of cubic nonlinearities of the second mode α 3 and the detuning parameter σ 2 respectively. Both modes shift to the left for increasing linear feedback gain v 1 and the coefficient of parametric excitation f 1 respectively

  8. Design of an optimal automatic regulator for regulating the power levels of a nuclear reactor in a wind power range

    International Nuclear Information System (INIS)

    Noori Khajavi, M.; Menhaj, M.B.; Ghofrani, M.B.

    2000-01-01

    Nuclear power reactors are, in nature nonlinear and time varying. These characteristics must be considered, if large power variations occur in their working regime. In this paper a robust optimal self-tuning regulator for regulating the power of a nuclear reactor has been designed and simulated. The proposed controller is capable of regulating power levels in a wide power range (10% to 100% power levels). The controller achieves a fast and good transient response. The simulation results show that the proposed controller outperforms the fixed optimal control recently cited in the literature for nuclear power plants

  9. Smart building temperature control using occupant feedback

    Science.gov (United States)

    Gupta, Santosh K.

    This work was motivated by the problem of computing optimal commonly-agreeable thermal settings in spaces with multiple occupants. In this work we propose algorithms that take into account each occupant's preferences along with the thermal correlations between different zones in a building, to arrive at optimal thermal settings for all zones of the building in a coordinated manner. In the first part of this work we incorporate active occupant feedback to minimize aggregate user discomfort and total energy cost. User feedback is used to estimate the users comfort range, taking into account possible inaccuracies in the feedback. The control algorithm takes the energy cost into account, trading it off optimally with the aggregate user discomfort. A lumped heat transfer model based on thermal resistance and capacitance is used to model a multi-zone building. We provide a stability analysis and establish convergence of the proposed solution to a desired temperature that minimizes the sum of energy cost and aggregate user discomfort. However, for convergence to the optimal, sufficient separation between the user feedback frequency and the dynamics of the system is necessary; otherwise, the user feedback provided do not correctly reflect the effect of current control input value on user discomfort. The algorithm is further extended using singular perturbation theory to determine the minimum time between successive user feedback solicitations. Under sufficient time scale separation, we establish convergence of the proposed solution. Simulation study and experimental runs on the Watervliet based test facility demonstrates performance of the algorithm. In the second part we develop a consensus algorithm for attaining a common temperature set-point that is agreeable to all occupants of a zone in a typical multi-occupant space. The information on the comfort range functions is indeed held privately by each occupant. Using occupant differentiated dynamically adjusted prices as

  10. Active tilting-pad journal bearings supporting flexible rotors: Part II–The model-based feedback-controlled lubrication

    DEFF Research Database (Denmark)

    Salazar, Jorge Andrés González; Santos, Ilmar

    2017-01-01

    This is part II of a twofold paper series dealing with the design and implementation of model-based controllers meant for assisting the hybrid and developing the feedback-controlled lubrication regimes in active tilting pad journal bearings (active TPJBs). In both papers theoretical and experimen...... derived in part I. Results show further suppression of resonant vibrations when using the feedback-controlled or active lubrication, overweighting the reduction already achieved with hybrid lubrication, thus improving the whole machine dynamic performance.......This is part II of a twofold paper series dealing with the design and implementation of model-based controllers meant for assisting the hybrid and developing the feedback-controlled lubrication regimes in active tilting pad journal bearings (active TPJBs). In both papers theoretical...... and experimental analyses are presented with focus on the reduction of rotor lateral vibration. This part is devoted to synthesising model-based LQG optimal controllers (LQR regulator + Kalman Filter) for the feedback-controlled lubrication and is based upon the mathematical model of the rotor-bearing system...

  11. STATE REGULATION OF FRANCHISING IN THE EU MEMBER COUNTRIES

    Directory of Open Access Journals (Sweden)

    Solomiya Ohinok

    2015-11-01

    Full Text Available In despite of extensive research of franchising in the scientific community, there are a lot of unresolved issues relating to franchising, in particular its regulation at the national level and at the level of the European Union that is why the purpose of the paper is to summarise and present the difference between state regulation of franchising in the EU member states and to research the basic principles of state regulation of franchising in the EU also to analyze legislation of the franchise relationship. Methodology. The survey is based on a comparison of data from all EU member countries and analisis of the legal framework of each country in particular and in general EU legislation. The article is devoted to a detailed analysis of main features of the franchise business in Europe. The mechanism of implementation of franchise relations between EU member states are studied. Government regulation of franchising in the EU member states are investigated. The rate of growth of franchising in Europe are analized. Results. By comparing different state laws and regulations of franchising we have identified the most effective and productive. We divided counties into two groups due to their regulation of franchising: countries which do not have a special government regulation of franchising; the countries which have state regulation of franchising; countries which have government regulation of franchising and it is governed by EU law, countries in which regulation is carried out in accordance with EU law. Thus, results of the survey showed that government regulation of franchising, as well as its regulation at the level of EU institutions have a positive impact on the development of franchising relationships. Practical implications of the results of the paper will help to develop well known network of franchise bussiness without legislative interference. Value/originality. It is first time we have grouped countries due to the main aspects of state

  12. A stage structure pest management model with impulsive state feedback control

    Science.gov (United States)

    Pang, Guoping; Chen, Lansun; Xu, Weijian; Fu, Gang

    2015-06-01

    A stage structure pest management model with impulsive state feedback control is investigated. We get the sufficient condition for the existence of the order-1 periodic solution by differential equation geometry theory and successor function. Further, we obtain a new judgement method for the stability of the order-1 periodic solution of the semi-continuous systems by referencing the stability analysis for limit cycles of continuous systems, which is different from the previous method of analog of Poincarè criterion. Finally, we analyze numerically the theoretical results obtained.

  13. Partial state feedback control of chaotic neural network and its application

    International Nuclear Information System (INIS)

    He Guoguang; Shrimali, Manish Dev; Aihara, Kazuyuki

    2007-01-01

    The chaos control in the chaotic neural network is studied using the partial state feedback with a control signal from a few control neurons. The controlled CNN converges to one of the stored patterns with a period which depends on the initial conditions, i.e., the set of control neurons and other control parameters. We show that the controlled CNN can distinguish between two initial patterns even if they have a small difference. This implies that such a controlled CNN can be feasibly applied to information processing such as pattern recognition

  14. Adaptive neural network output feedback control for stochastic nonlinear systems with unknown dead-zone and unmodeled dynamics.

    Science.gov (United States)

    Tong, Shaocheng; Wang, Tong; Li, Yongming; Zhang, Huaguang

    2014-06-01

    This paper discusses the problem of adaptive neural network output feedback control for a class of stochastic nonlinear strict-feedback systems. The concerned systems have certain characteristics, such as unknown nonlinear uncertainties, unknown dead-zones, unmodeled dynamics and without the direct measurements of state variables. In this paper, the neural networks (NNs) are employed to approximate the unknown nonlinear uncertainties, and then by representing the dead-zone as a time-varying system with a bounded disturbance. An NN state observer is designed to estimate the unmeasured states. Based on both backstepping design technique and a stochastic small-gain theorem, a robust adaptive NN output feedback control scheme is developed. It is proved that all the variables involved in the closed-loop system are input-state-practically stable in probability, and also have robustness to the unmodeled dynamics. Meanwhile, the observer errors and the output of the system can be regulated to a small neighborhood of the origin by selecting appropriate design parameters. Simulation examples are also provided to illustrate the effectiveness of the proposed approach.

  15. Analysis of reactor power behaviour using estimation of period for the gain adaptation in a state feedback controller

    International Nuclear Information System (INIS)

    Benitez R, J.S.; Perez C, J.H.; Rivero G, T.

    2008-01-01

    In this paper a novel procedure for power regulation in a TRIGA Mark III nuclear reactor is presented. The control scheme combines state variable feedback with a first order predictor, which is incorporated to speed up the power response of the reactor without exceeding the safety requirement imposed by the reactor period. The simulation results using the proposed control strategy attains different values of steady-state power from different values of initial power in short time, complying at all times with the safety restriction imposed on the reactor period. The predictor, derived from the theory of first order numerical integration, produces very good results during the ascent of power. These results include a fast response and independence of the wide variety of potential operating conditions something not easy and even impossible to obtain with other procedures. By using this control scheme, the reactor period is maintained within safety limits during the start up of the reactor, which is normally the operating condition where an occurrence of a period scram is common. However, the predictor can not be used when the power is reaching the desired power level because the instantaneous power increases far above the desired level. Thus, when the power increases above certain power level, the state feedback gain is set constant to a predefined value. This causes some oscillations that decrease in a few seconds. Afterwards, the power response smoothly approaches, with a small overshoot, the desired power. This constraint on the use of the predictor prevents the unbounded increase of the neutron power. The control law proposed requires all the system's state variables. Since only the neutron power is available, it is necessary the estimation of the non measurable states. The key issue of the existence of a solution to this problem has been previously considered. One of the conclusions is that the point kinetic equations are observable under certain restrictions on

  16. Research on Cascade Reservoirs’ Short-Term Optimal Operation under the Effect of Reverse Regulation

    Directory of Open Access Journals (Sweden)

    Changming Ji

    2018-06-01

    Full Text Available Currently research on joint operation of a large reservoir and its re-regulating reservoir focuses on either water quantity regulation or water head regulation. The accuracy of relevant models is in need of improvement if the influence of factors such as water flow hysteresis and the aftereffect of tail water level variation are taken into consideration. In this paper, given the actual production of Pankou-Xiaoxuan cascade hydropower stations that combines two operation modes (‘electricity to water’ and ‘water to electricity’, a coupling model of their short-term optimal operation is developed, which considers Xiaoxuan reservoir’s regulating effect on Pankou reservoir’s outflow volume and water head. Factors such as water flow hysteresis and the aftereffect of tail water level variation are also considered to enhance the model’s accuracy. The Backward Propagation (BP neural network is employed for precise calculation of the downstream reservoir’s inflow and the upstream reservoir’s tail water level. Besides, we put forth Accompanying Progressive Optimality Algorithm (APOA to solve the coupling model with aftereffect. An example is given to verify the scientificity of the proposed model and the advantages of APOA. Through analysis of the model calculation results, the optimal operation rules of the cascade reservoirs are obtained in terms of water quantity regulation and water head regulation, which can provide scientific reference for cascade reservoirs’ optimal operation.

  17. The Role of Feedback Contingency in Perceptual Category Learning

    Science.gov (United States)

    Ashby, F. Gregory; Vucovich, Lauren E.

    2016-01-01

    Feedback is highly contingent on behavior if it eventually becomes easy to predict, and weakly contingent on behavior if it remains difficult or impossible to predict even after learning is complete. Many studies have demonstrated that humans and nonhuman animals are highly sensitive to feedback contingency, but no known studies have examined how feedback contingency affects category learning, and current theories assign little or no importance to this variable. Two experiments examined the effects of contingency degradation on rule-based and information-integration category learning. In rule-based tasks, optimal accuracy is possible with a simple explicit rule, whereas optimal accuracy in information-integration tasks requires integrating information from two or more incommensurable perceptual dimensions. In both experiments, participants each learned rule-based or information-integration categories under either high or low levels of feedback contingency. The exact same stimuli were used in all four conditions and optimal accuracy was identical in every condition. Learning was good in both high-contingency conditions, but most participants showed little or no evidence of learning in either low-contingency condition. Possible causes of these effects are discussed, as well as their theoretical implications. PMID:27149393

  18. Compressive Sensing for Feedback Reduction in Wireless Multiuser Networks

    KAUST Repository

    Elkhalil, Khalil

    2015-05-01

    User/relay selection is a simple technique that achieves spatial diversity in multiuser networks. However, for user/relay selection algorithms to make a selection decision, channel state information (CSI) from all cooperating users/relays is usually required at a central node. This requirement poses two important challenges. Firstly, CSI acquisition generates a great deal of feedback overhead (air-time) that could result in significant transmission delays. Secondly, the fed-back channel information is usually corrupted by additive noise. This could lead to transmission outages if the central node selects the set of cooperating relays based on inaccurate feedback information. Motivated by the aforementioned challenges, we propose a limited feedback user/relay selection scheme that is based on the theory of compressed sensing. Firstly, we introduce a limited feedback relay selection algorithm for a multicast relay network. The proposed algorithm exploits the theory of compressive sensing to first obtain the identity of the “strong” relays with limited feedback air-time. Following that, the CSI of the selected relays is estimated using minimum mean square error estimation without any additional feedback. To minimize the effect of noise on the fed-back CSI, we introduce a back-off strategy that optimally backs-off on the noisy received CSI. In the second part of the thesis, we propose a feedback reduction scheme for full-duplex relay-aided multiuser networks. The proposed scheme permits the base station (BS) to obtain channel state information (CSI) from a subset of strong users under substantially reduced feedback overhead. More specifically, we cast the problem of user identification and CSI estimation as a block sparse signal recovery problem in compressive sensing (CS). Using existing CS block recovery algorithms, we first obtain the identity of the strong users and then estimate their CSI using the best linear unbiased estimator (BLUE). Moreover, we derive the

  19. A conserved SREBP-1/phosphatidylcholine feedback circuit regulates lipogenesis in metazoans.

    Science.gov (United States)

    Walker, Amy K; Jacobs, René L; Watts, Jennifer L; Rottiers, Veerle; Jiang, Karen; Finnegan, Deirdre M; Shioda, Toshi; Hansen, Malene; Yang, Fajun; Niebergall, Lorissa J; Vance, Dennis E; Tzoneva, Monika; Hart, Anne C; Näär, Anders M

    2011-11-11

    Sterol regulatory element-binding proteins (SREBPs) activate genes involved in the synthesis and trafficking of cholesterol and other lipids and are critical for maintaining lipid homeostasis. Aberrant SREBP activity, however, can contribute to obesity, fatty liver disease, and insulin resistance, hallmarks of metabolic syndrome. Our studies identify a conserved regulatory circuit in which SREBP-1 controls genes in the one-carbon cycle, which produces the methyl donor S-adenosylmethionine (SAMe). Methylation is critical for the synthesis of phosphatidylcholine (PC), a major membrane component, and we find that blocking SAMe or PC synthesis in C. elegans, mouse liver, and human cells causes elevated SREBP-1-dependent transcription and lipid droplet accumulation. Distinct from negative regulation of SREBP-2 by cholesterol, our data suggest a feedback mechanism whereby maturation of nuclear, transcriptionally active SREBP-1 is controlled by levels of PC. Thus, nutritional or genetic conditions limiting SAMe or PC production may activate SREBP-1, contributing to human metabolic disorders. Copyright © 2011 Elsevier Inc. All rights reserved.

  20. Neural activations associated with feedback and retrieval success

    Science.gov (United States)

    Wiklund-Hörnqvist, Carola; Andersson, Micael; Jonsson, Bert; Nyberg, Lars

    2017-11-01

    There is substantial behavioral evidence for a phenomenon commonly called "the testing effect", i.e. superior memory performance after repeated testing compared to re-study of to-be-learned materials. However, considerably less is known about the underlying neuro-cognitive processes that are involved in the initial testing phase, and thus underlies the actual testing effect. Here, we investigated functional brain activity related to test-enhanced learning with feedback. Subjects learned foreign vocabulary across three consecutive tests with correct-answer feedback. Functional brain-activity responses were analyzed in relation to retrieval and feedback events, respectively. Results revealed up-regulated activity in fronto-striatal regions during the first successful retrieval, followed by a marked reduction in activity as a function of improved learning. Whereas feedback improved behavioral performance across consecutive tests, feedback had a negligable role after the first successful retrieval for functional brain-activity modulations. It is suggested that the beneficial effects of test-enhanced learning is regulated by feedback-induced updating of memory representations, mediated via the striatum, that might underlie the stabilization of memory commonly seen in behavioral studies of the testing effect.

  1. Feedback, Lineages and Self-Organizing Morphogenesis.

    Directory of Open Access Journals (Sweden)

    Sameeran Kunche

    2016-03-01

    Full Text Available Feedback regulation of cell lineage progression plays an important role in tissue size homeostasis, but whether such feedback also plays an important role in tissue morphogenesis has yet to be explored. Here we use mathematical modeling to show that a particular feedback architecture in which both positive and negative diffusible signals act on stem and/or progenitor cells leads to the appearance of bistable or bi-modal growth behaviors, ultrasensitivity to external growth cues, local growth-driven budding, self-sustaining elongation, and the triggering of self-organization in the form of lamellar fingers. Such behaviors arise not through regulation of cell cycle speeds, but through the control of stem or progenitor self-renewal. Even though the spatial patterns that arise in this setting are the result of interactions between diffusible factors with antagonistic effects, morphogenesis is not the consequence of Turing-type instabilities.

  2. Feedback, Lineages and Self-Organizing Morphogenesis

    Science.gov (United States)

    Calof, Anne L.; Lowengrub, John S.; Lander, Arthur D.

    2016-01-01

    Feedback regulation of cell lineage progression plays an important role in tissue size homeostasis, but whether such feedback also plays an important role in tissue morphogenesis has yet to be explored. Here we use mathematical modeling to show that a particular feedback architecture in which both positive and negative diffusible signals act on stem and/or progenitor cells leads to the appearance of bistable or bi-modal growth behaviors, ultrasensitivity to external growth cues, local growth-driven budding, self-sustaining elongation, and the triggering of self-organization in the form of lamellar fingers. Such behaviors arise not through regulation of cell cycle speeds, but through the control of stem or progenitor self-renewal. Even though the spatial patterns that arise in this setting are the result of interactions between diffusible factors with antagonistic effects, morphogenesis is not the consequence of Turing-type instabilities. PMID:26989903

  3. State dependent optimization of measurement policy

    Science.gov (United States)

    Konkarikoski, K.

    2010-07-01

    Measurements are the key to rational decision making. Measurement information generates value, when it is applied in the decision making. An investment cost and maintenance costs are associated with each component of the measurement system. Clearly, there is - under a given set of scenarios - a measurement setup that is optimal in expected (discounted) utility. This paper deals how the measurement policy optimization is affected by different system states and how this problem can be tackled.

  4. State dependent optimization of measurement policy

    International Nuclear Information System (INIS)

    Konkarikoski, K

    2010-01-01

    Measurements are the key to rational decision making. Measurement information generates value, when it is applied in the decision making. An investment cost and maintenance costs are associated with each component of the measurement system. Clearly, there is - under a given set of scenarios - a measurement setup that is optimal in expected (discounted) utility. This paper deals how the measurement policy optimization is affected by different system states and how this problem can be tackled.

  5. Logistics of radioactive materials: optimization of laws and regulations

    International Nuclear Information System (INIS)

    Akakiev, B.V.; Makarevich, I.M.; Nesterov, V.P.

    2009-01-01

    The article considers the problems of the Russian authorization system in the field of radioactive materials (RM) logistics which does not meet the needs of their application in medicine, science and industry. To correct the situation, first of all, it is necessary to revise the licensing system. For optimization of licensing in the field of RM transportation, a radical revision is needed for the Regulations of transportation of dangerous cargoes by automobiles, sanitary regulations, the GOST Dangerous Cargoes, numerous federal codes and norms issued by Rostekhnadzor in recent years. It is also necessary to review and coordinate various sanitary regulations for radiation safety, develop the Agreement on transit transportation of RM between the countries of the CIS [ru

  6. Homogeneous Stabilizer by State Feedback for Switched Nonlinear Systems Using Multiple Lyapunov Functions’ Approach

    Directory of Open Access Journals (Sweden)

    Hui Ye

    2017-01-01

    Full Text Available This paper investigates the problem of global stabilization for a class of switched nonlinear systems using multiple Lyapunov functions (MLFs. The restrictions on nonlinearities are neither linear growth condition nor Lipschitz condition with respect to system states. Based on adding a power integrator technique, we design homogeneous state feedback controllers of all subsystems and a switching law to guarantee that the closed-loop system is globally asymptotically stable. Finally, an example is given to illustrate the validity of the proposed control scheme.

  7. Weighted congestion coefficient feedback in intelligent transportation systems

    International Nuclear Information System (INIS)

    Dong Chuanfei; Ma Xu; Wang Binghong

    2010-01-01

    In traffic systems, a reasonable information feedback can improve road capacity. In this Letter, we study dynamics of traffic flow with real-time information. And the influence of a feedback strategy named Weighted Congestion Coefficient Feedback Strategy (WCCFS) is introduced, based on a two-route scenario in which dynamic information can be generated and displayed on the board to guide road users to make a choice. Our model incorporates the effects of adaptability into the cellular automaton models of traffic flow and simulation results adopting this optimal information feedback strategy have demonstrated high efficiency in controlling spatial distribution of traffic patterns compared with the other three information feedback strategies, i.e., vehicle number and flux.

  8. Probabilistic Cloning of Three Real States with Optimal Success Probabilities

    Science.gov (United States)

    Rui, Pin-shu

    2017-06-01

    We investigate the probabilistic quantum cloning (PQC) of three real states with average probability distribution. To get the analytic forms of the optimal success probabilities we assume that the three states have only two pairwise inner products. Based on the optimal success probabilities, we derive the explicit form of 1 →2 PQC for cloning three real states. The unitary operation needed in the PQC process is worked out too. The optimal success probabilities are also generalized to the M→ N PQC case.

  9. Nonlatching positive feedback enables robust bimodality by decoupling expression noise from the mean

    Energy Technology Data Exchange (ETDEWEB)

    Razooky, Brandon S. [Rockefeller Univ., New York, NY (United States). Lab. of Virology and Infectious Disease; Gladstone Institutes (Virology and Immunology), San Francisco, CA (United States); Univ. of California, San Francisco, CA (United States); Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Center for Nanophase Materials Science (CNMS); Univ. of Tennessee, Knoxville, TN (United States). Bredesen Center for Interdisciplinary; Cao, Youfang [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Hansen, Maike M. K. [Gladstone Institutes (Virology and Immunology), San Francisco, CA (United States); Perelson, Alan S. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Simpson, Michael L. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Center for Nanophase Materials Science (CNMS); Univ. of Tennessee, Knoxville, TN (United States). Bredesen Center for Interdisciplinary; Weinberger, Leor S. [Gladstone Institutes (Virology and Immunology), San Francisco, CA (United States); Univ. of California, San Francisco, CA (United States). Dept. of Biochemistry and Biophysics; Univ. of California, San Francisco, CA (United States). QB3: California Inst. of Quantitative Biosciences; Univ. of California, San Francisco, CA (United States). Dept. of Pharmaceutical Chemistry

    2017-10-18

    Fundamental to biological decision-making is the ability to generate bimodal expression patterns where two alternate expression states simultaneously exist. Here in this study, we use a combination of single-cell analysis and mathematical modeling to examine the sources of bimodality in the transcriptional program controlling HIV’s fate decision between active replication and viral latency. We find that the HIV Tat protein manipulates the intrinsic toggling of HIV’s promoter, the LTR, to generate bimodal ON-OFF expression, and that transcriptional positive feedback from Tat shifts and expands the regime of LTR bimodality. This result holds for both minimal synthetic viral circuits and full-length virus. Strikingly, computational analysis indicates that the Tat circuit’s non-cooperative ‘non-latching’ feedback architecture is optimized to slow the promoter’s toggling and generate bimodality by stochastic extinction of Tat. In contrast to the standard Poisson model, theory and experiment show that non-latching positive feedback substantially dampens the inverse noise-mean relationship to maintain stochastic bimodality despite increasing mean-expression levels. Given the rapid evolution of HIV, the presence of a circuit optimized to robustly generate bimodal expression appears consistent with the hypothesis that HIV’s decision between active replication and latency provides a viral fitness advantage. More broadly, the results suggest that positive-feedback circuits may have evolved not only for signal amplification but also for robustly generating bimodality by decoupling expression fluctuations (noise) from mean expression levels.

  10. Design of output feedback UPFC controller for damping of electromechanical oscillations using PSO

    Energy Technology Data Exchange (ETDEWEB)

    Shayeghi, H. [Technical Engineering Dept., Univ. of Mohaghegh Ardabili, Ardabil (Iran); Shayanfar, H.A. [Center of Excellence for Power Automation and Operation, Electrical Engineering Dept., Iran Univ. of Science and Technology, Tehran (Iran); Jalilzadeh, S.; Safari, A. [Technical Engineering Dept., Zanjan Univ., Zanjan (Iran)

    2009-10-15

    In this paper, a novel method for the design of output feedback controller for unified power flow controller (UPFC) is developed. The selection of the output feedback gains for the UPFC controllers is converted to an optimization problem with the time domain-based objective function which is solved by a particle swarm optimization technique (PSO) that has a strong ability to find the most optimistic results. Only local and available state variables are adopted as the input signals of each controller for the decentralized design. Thus, structure of the designed UPFC controller is simple and easy to implement. To ensure the robustness of the proposed stabilizers, the design process takes into account a wide range of operating conditions and system configurations. The effectiveness of the proposed controller for damping low frequency oscillations is tested and demonstrated through nonlinear time-domain simulation and some performance indices studies. The results analysis reveals that the designed PSO-based output feedback UPFC damping controller has an excellent capability in damping power system low frequency oscillations and enhance greatly the dynamic stability of the power systems. Moreover, the system performance analysis under different operating conditions show that the {delta}{sub E} based controller is superior to both the m{sub B} based controller and conventional power system stablizer. (author)

  11. Cross-entropy optimization for neuromodulation.

    Science.gov (United States)

    Brar, Harleen K; Yunpeng Pan; Mahmoudi, Babak; Theodorou, Evangelos A

    2016-08-01

    This study presents a reinforcement learning approach for the optimization of the proportional-integral gains of the feedback controller represented in a computational model of epilepsy. The chaotic oscillator model provides a feedback control systems view of the dynamics of an epileptic brain with an internal feedback controller representative of the natural seizure suppression mechanism within the brain circuitry. Normal and pathological brain activity is simulated in this model by adjusting the feedback gain values of the internal controller. With insufficient gains, the internal controller cannot provide enough feedback to the brain dynamics causing an increase in correlation between different brain sites. This increase in synchronization results in the destabilization of the brain dynamics, which is representative of an epileptic seizure. To provide compensation for an insufficient internal controller an external controller is designed using proportional-integral feedback control strategy. A cross-entropy optimization algorithm is applied to the chaotic oscillator network model to learn the optimal feedback gains for the external controller instead of hand-tuning the gains to provide sufficient control to the pathological brain and prevent seizure generation. The correlation between the dynamics of neural activity within different brain sites is calculated for experimental data to show similar dynamics of epileptic neural activity as simulated by the network of chaotic oscillators.

  12. COA based robust output feedback UPFC controller design

    Energy Technology Data Exchange (ETDEWEB)

    Shayeghi, H., E-mail: hshayeghi@gmail.co [Technical Engineering Department, University of Mohaghegh Ardabili, Ardabil (Iran, Islamic Republic of); Shayanfar, H.A. [Center of Excellence for Power System Automation and Operation, Electrical Engineering Department, Iran University of Science and Technology, Tehran (Iran, Islamic Republic of); Jalilzadeh, S.; Safari, A. [Technical Engineering Department, Zanjan University, Zanjan (Iran, Islamic Republic of)

    2010-12-15

    In this paper, a novel method for the design of output feedback controller for unified power flow controller (UPFC) using chaotic optimization algorithm (COA) is developed. Chaotic optimization algorithms, which have the features of easy implementation, short execution time and robust mechanisms of escaping from the local optimum, is a promising tool for the engineering applications. The selection of the output feedback gains for the UPFC controllers is converted to an optimization problem with the time domain-based objective function which is solved by a COA based on Lozi map. Since chaotic mapping enjoys certainty, ergodicity and the stochastic property, the proposed chaotic optimization problem introduces chaos mapping using Lozi map chaotic sequences which increases its convergence rate and resulting precision. To ensure the robustness of the proposed stabilizers, the design process takes into account a wide range of operating conditions and system configurations. The effectiveness of the proposed controller for damping low frequency oscillations is tested and demonstrated through non-linear time-domain simulation and some performance indices studies. The results analysis reveals that the designed COA based output feedback UPFC damping controller has an excellent capability in damping power system low frequency oscillations and enhance greatly the dynamic stability of the power systems.

  13. Further results on global state feedback stabilization of nonlinear high-order feedforward systems.

    Science.gov (United States)

    Xie, Xue-Jun; Zhang, Xing-Hui

    2014-03-01

    In this paper, by introducing a combined method of sign function, homogeneous domination and adding a power integrator, and overcoming several troublesome obstacles in the design and analysis, the problem of state feedback control for a class of nonlinear high-order feedforward systems with the nonlinearity's order being relaxed to an interval rather than a fixed point is solved. Copyright © 2013 ISA. Published by Elsevier Ltd. All rights reserved.

  14. Quantifying the relative contributions of divisive and subtractive feedback to rhythm generation.

    Directory of Open Access Journals (Sweden)

    Joël Tabak

    2011-04-01

    Full Text Available Biological systems are characterized by a high number of interacting components. Determining the role of each component is difficult, addressed here in the context of biological oscillations. Rhythmic behavior can result from the interplay of positive feedback that promotes bistability between high and low activity, and slow negative feedback that switches the system between the high and low activity states. Many biological oscillators include two types of negative feedback processes: divisive (decreases the gain of the positive feedback loop and subtractive (increases the input threshold that both contribute to slowly move the system between the high- and low-activity states. Can we determine the relative contribution of each type of negative feedback process to the rhythmic activity? Does one dominate? Do they control the active and silent phase equally? To answer these questions we use a neural network model with excitatory coupling, regulated by synaptic depression (divisive and cellular adaptation (subtractive feedback. We first attempt to apply standard experimental methodologies: either passive observation to correlate the variations of a variable of interest to system behavior, or deletion of a component to establish whether a component is critical for the system. We find that these two strategies can lead to contradictory conclusions, and at best their interpretive power is limited. We instead develop a computational measure of the contribution of a process, by evaluating the sensitivity of the active (high activity and silent (low activity phase durations to the time constant of the process. The measure shows that both processes control the active phase, in proportion to their speed and relative weight. However, only the subtractive process plays a major role in setting the duration of the silent phase. This computational method can be used to analyze the role of negative feedback processes in a wide range of biological rhythms.

  15. Operation of PEP longitudinal feedback system

    International Nuclear Information System (INIS)

    Allen, M.A.; Karvonen, L.G.; McConnell, R.A.; Schwarz, H.

    1981-03-01

    In order to suppress longitudinal coupled-bunch oscillations which might limit the capabilities of PEP, the 18 GeV e + e - storage ring at SLAC, a longitudinal feedback system is utilized. A frequency domain feedback system was chosen with the frequency spectrum of the stored beam being sampled close to a symmetry point in the ring where the feedback cavity itself is also located. The symmetry point chosen is symmetry point 5 which lies half-way between interaction regions 4 and 6. The system has been installed in PEP and is now operational. However, at stored currents up to the maximum stored in PEP to date at 14.5 GeV (approximately 40 mA in 6 bunches), the ring has been stable to all modes of longitudinal coupled-bunch oscillations both barycentric and the other fundamental modes. By deliberately detuning the main accelerating cavities, small multibunch oscillations can be introduced which, in turn, can be damped by the feedback system. Under optimized beam conditions the feedback system could be adjusted to positive feedback and excite oscillations with relatively small power to the feedback cavity. This will be described along with other details of the system

  16. An Improved Multi-Objective Artificial Bee Colony Optimization Algorithm with Regulation Operators

    Directory of Open Access Journals (Sweden)

    Jiuyuan Huo

    2017-02-01

    Full Text Available To achieve effective and accurate optimization for multi-objective optimization problems, a multi-objective artificial bee colony algorithm with regulation operators (RMOABC inspired by the intelligent foraging behavior of honey bees was proposed in this paper. The proposed algorithm utilizes the Pareto dominance theory and takes advantage of adaptive grid and regulation operator mechanisms. The adaptive grid technique is used to adaptively assess the Pareto front maintained in an external archive and the regulation operator is used to balance the weights of the local search and the global search in the evolution of the algorithm. The performance of RMOABC was evaluated in comparison with other nature inspired algorithms includes NSGA-II and MOEA/D. The experiments results demonstrated that the RMOABC approach has better accuracy and minimal execution time.

  17. Pseudo-Haptic Feedback in Teleoperation.

    Science.gov (United States)

    Neupert, Carsten; Matich, Sebastian; Scherping, Nick; Kupnik, Mario; Werthschutzky, Roland; Hatzfeld, Christian

    2016-01-01

    In this paper, we develop possible realizations of pseudo-haptic feedback in teleoperation systems based on existing works for pseudo-haptic feedback in virtual reality and the intended applications. We derive four potential factors affecting the performance of haptic feedback (calculation operator, maximum displacement, offset force, and scaling factor), which are analyzed in three compliance identification experiments. First, we analyze the principle usability of pseudo-haptic feedback by comparing information transfer measures for teleoperation and direct interaction. Pseudo-haptic interaction yields well above-chance performance, while direct interaction performs almost perfectly. In order to optimize pseudo-haptic feedback, in the second study we perform a full-factorial experimental design with 36 subjects performing 6,480 trials with 36 different treatments. Information transfer ranges from 0.68 bit to 1.72 bit in a task with a theoretical maximum of 2.6 bit, with a predominant effect of the calculation operator and a minor effect of the maximum displacement. In a third study, short- and long-term learning effects are analyzed. Learning effects regarding the performance of pseudo-haptic feedback cannot be observed for single-day experiments. Tests over 10 days show a maximum increase in information transfer of 0.8 bit. The results show the feasibility of pseudo-haptic feedback for teleoperation and can be used as design basis for task-specific systems.

  18. Task-dependent vestibular feedback responses in reaching.

    Science.gov (United States)

    Keyser, Johannes; Medendorp, W Pieter; Selen, Luc P J

    2017-07-01

    When reaching for an earth-fixed object during self-rotation, the motor system should appropriately integrate vestibular signals and sensory predictions to compensate for the intervening motion and its induced inertial forces. While it is well established that this integration occurs rapidly, it is unknown whether vestibular feedback is specifically processed dependent on the behavioral goal. Here, we studied whether vestibular signals evoke fixed responses with the aim to preserve the hand trajectory in space or are processed more flexibly, correcting trajectories only in task-relevant spatial dimensions. We used galvanic vestibular stimulation to perturb reaching movements toward a narrow or a wide target. Results show that the same vestibular stimulation led to smaller trajectory corrections to the wide than the narrow target. We interpret this reduced compensation as a task-dependent modulation of vestibular feedback responses, tuned to minimally intervene with the task-irrelevant dimension of the reach. These task-dependent vestibular feedback corrections are in accordance with a central prediction of optimal feedback control theory and mirror the sophistication seen in feedback responses to mechanical and visual perturbations of the upper limb. NEW & NOTEWORTHY Correcting limb movements for external perturbations is a hallmark of flexible sensorimotor behavior. While visual and mechanical perturbations are corrected in a task-dependent manner, it is unclear whether a vestibular perturbation, naturally arising when the body moves, is selectively processed in reach control. We show, using galvanic vestibular stimulation, that reach corrections to vestibular perturbations are task dependent, consistent with a prediction of optimal feedback control theory. Copyright © 2017 the American Physiological Society.

  19. The State Fiscal Policy: Determinants and Optimization of Financial Flows

    Directory of Open Access Journals (Sweden)

    Sitash Tetiana D.

    2017-03-01

    Full Text Available The article outlines the determinants of the state fiscal policy at the present stage of global transformations. Using the principles of financial science it is determined that regulation of financial flows within the fiscal sphere, namely centralization and redistribution of the GDP, which results in the regulation of the financial capacity of economic agents, is of importance. It is emphasized that the urgent measure for improving the tax model is re-considering the provision of fiscal incentives, which are used to stimulate the accumulation of capital, investment activity, innovation, increase of the competitiveness of national products, expansion of exports, increase of the level of the population employment. The necessity of applying the instruments of fiscal regulation of financial flows, which should take place on the basis of institutional economics emphasizing the analysis of institutional changes, the evolution of institutions and their impact on the behavior of participants of economic relations. At the same time it is determined that the maximum effect of fiscal regulation of financial flows is ensured when application of fiscal instruments is aimed not only at achieving the target values of parameters of financial flows but at overcoming institutional deformations as well. It is determined that the optimal movement of financial flows enables creating favorable conditions for development and maintenance of financial balance in the society and achievement of the necessary level of competitiveness of the national economy.

  20. Nonclassical state generation for linear quantum systems via nonlinear feedback control

    International Nuclear Information System (INIS)

    Ohki, Kentaro; Tsumura, Koji; Takeuchi, Reiji

    2017-01-01

    In this paper, we propose a measurement nonlinear feedback control scheme to generate Wigner-function negativity in an optical cavity having dynamics described as a linear quantum system. In general, linear optical quantum systems can be easily constructed with reliable devices; therefore, the idea of constructing the entire system with such an optical system and nonlinear feedback is reasonable for generating Wigner-function negativity. However, existing studies have insufficiently examined the realizability or actual implementation of feedback control, which essentially requires fast responses from the sensors and actuators. In order to solve this problem, we consider the realizable feedback control of the optical phase of a pumping beam supplied to a cavity by using electro-optical modulation, which can be utilized as a fast control actuator. Then, we introduce mathematical models of the feedback-controlled system and evaluate its effect on the generation of the Wigner-function negativity by using numerical simulation. Through various numerical simulations, we show that the proposed feedback control can effectively generate the negativity of the Wigner function. (paper)

  1. Periodic feedback stabilization for linear periodic evolution equations

    CERN Document Server

    Wang, Gengsheng

    2016-01-01

    This book introduces a number of recent advances regarding periodic feedback stabilization for linear and time periodic evolution equations. First, it presents selected connections between linear quadratic optimal control theory and feedback stabilization theory for linear periodic evolution equations. Secondly, it identifies several criteria for the periodic feedback stabilization from the perspective of geometry, algebra and analyses respectively. Next, it describes several ways to design periodic feedback laws. Lastly, the book introduces readers to key methods for designing the control machines. Given its coverage and scope, it offers a helpful guide for graduate students and researchers in the areas of control theory and applied mathematics.

  2. Cytokinins and auxins control the expression of a gene in Nicotiana plumbaginifolia cells by feedback regulation.

    Science.gov (United States)

    Dominov, J A; Stenzler, L; Lee, S; Schwarz, J J; Leisner, S; Howell, S H

    1992-01-01

    Both cytokinin (N6-benzyladenine [BA]) and auxin (2,4-dichlorophenoxyacetic acid [2,4-D]) stimulate the accumulation of an mRNA, represented by the cDNA pLS216, in Nicotiana plumbaginifolia suspension culture cells. The kinetics of RNA accumulation were different for the two hormones; however, the response to both was transient, and the magnitude of the response was dose dependent. Runoff transcription experiments demonstrated that the transient appearance of the RNA could be accounted for by feedback regulation of transcription and not by the induction of an RNA degradation system. The feedback mechanism appeared to desensitize the cells to further exposure of the hormone. In particular, cells became refractory to the subsequent addition of 2,4-D after the initial RNA accumulation response subsided. A very different response was observed when the second hormone was added to cells that had been desensitized to the first hormone. Under such conditions, BA produced a heightened response in cells desensitized to 2,4-D and vice versa. These findings support a model in which cytokinin further enhances the auxin response or prevents its feedback inhibition. The hormone-induced RNA accumulation was blocked by the protein kinase inhibitor staurosporin. On the other hand, the protein phosphatase inhibitor okadaic acid stimulated expression, and, in particular, okadaic acid was able to stimulate RNA accumulation in cells desensitized to auxin. This suggests that hormone activation involves phosphorylation of critical proteins on the hormone signaling pathway, whereas feedback inhibition may involve dephosphorylation of these proteins. The sequence of pLS216 is similar to genes in other plants that are stimulated by multiple agonists such as auxins, elicitors, and heavy metals, and to the gene encoding the stringent starvation protein in Escherichia coli. It is proposed that this gene family in various plants be called multiple stimulus response (msr) genes. PMID:1498603

  3. Optimizing adherence to advice from antimicrobial stewardship audit and feedback rounds.

    Science.gov (United States)

    Rawlins, Matthew D M; Sanfilippo, Frank M; Ingram, Paul R; McLellan, Duncan G J; Crawford, Colin; D'Orsogna, Luca; Dyer, John

    2018-02-01

    We examined adherence to antimicrobial stewardship prospective audit and feedback rounds in a rehabilitation service compared with the remainder of the acute hospital, and explored the reasons for this. Between October 2014 and December 2015, we retrospectively assessed the rate of non-adherence to advice from antimicrobial stewardship prospective audit and feedback rounds between the rehabilitation service and the acute hospital, along with the source of the patient referral. Compared with the rehabilitation service, acute hospital medical staff were almost twice as likely to not adhere to advice provided on antimicrobial stewardship prospective audit and feedback rounds (13.8% vs. 7.6%, p risk 1.8 [95% confidence interval 1.3, 2.5]). In the rehabilitation service, referrals were more likely to come from medical staff (61.9% vs. 16.3%, p model potentially applicable to other settings.

  4. Time-optimal thermalization of single-mode Gaussian states

    Science.gov (United States)

    Carlini, Alberto; Mari, Andrea; Giovannetti, Vittorio

    2014-11-01

    We consider the problem of time-optimal control of a continuous bosonic quantum system subject to the action of a Markovian dissipation. In particular, we consider the case of a one-mode Gaussian quantum system prepared in an arbitrary initial state and which relaxes to the steady state due to the action of the dissipative channel. We assume that the unitary part of the dynamics is represented by Gaussian operations which preserve the Gaussian nature of the quantum state, i.e., arbitrary phase rotations, bounded squeezing, and unlimited displacements. In the ideal ansatz of unconstrained quantum control (i.e., when the unitary phase rotations, squeezing, and displacement of the mode can be performed instantaneously), we study how control can be optimized for speeding up the relaxation towards the fixed point of the dynamics and we analytically derive the optimal relaxation time. Our model has potential and interesting applications to the control of modes of electromagnetic radiation and of trapped levitated nanospheres.

  5. Early growth response-1 negative feedback regulates skeletal muscle postprandial insulin sensitivity via activating Ptp1b transcription.

    Science.gov (United States)

    Wu, Jing; Tao, Wei-Wei; Chong, Dan-Yang; Lai, Shan-Shan; Wang, Chuang; Liu, Qi; Zhang, Tong-Yu; Xue, Bin; Li, Chao-Jun

    2018-03-15

    Postprandial insulin desensitization plays a critical role in maintaining whole-body glucose homeostasis by avoiding the excessive absorption of blood glucose; however, the detailed mechanisms that underlie how the major player, skeletal muscle, desensitizes insulin action remain to be elucidated. Herein, we report that early growth response gene-1 ( Egr-1) is activated by insulin in skeletal muscle and provides feedback inhibition that regulates insulin sensitivity after a meal. The inhibition of the transcriptional activity of Egr-1 enhanced the phosphorylation of the insulin receptor (InsR) and Akt, thus increasing glucose uptake in L6 myotubes after insulin stimulation, whereas overexpression of Egr-1 decreased insulin sensitivity. Furthermore, deletion of Egr-1 in the skeletal muscle improved systemic insulin sensitivity and glucose tolerance, which resulted in lower blood glucose levels after refeeding. Mechanistic analysis demonstrated that EGR-1 inhibited InsR phosphorylation and glucose uptake in skeletal muscle by binding to the proximal promoter region of protein tyrosine phosphatase-1B (PTP1B) and directly activating transcription. PTP1B knockdown largely restored insulin sensitivity and enhanced glucose uptake, even under conditions of EGR-1 overexpression. Our results indicate that EGR-1/PTP1B signaling negatively regulates postprandial insulin sensitivity and suggest a potential therapeutic target for the prevention and treatment of excessive glucose absorption.-Wu, J., Tao, W.-W., Chong, D.-Y., Lai, S.-S., Wang, C., Liu, Q., Zhang, T.-Y., Xue, B., Li, C.-J. Early growth response-1 negative feedback regulates skeletal muscle postprandial insulin sensitivity via activating Ptp1b transcription.

  6. The role of the regulator in promoting and evaluating safety culture. Operating experience feedback programme approach

    International Nuclear Information System (INIS)

    Perez, S.

    2002-01-01

    Promoting and Evaluating Safety Culture (S.C.) in Operating Organizations must be one of the main Nuclear Regulator goals to achieve. This can be possible only if each and every one of the regulatory activities inherently involves S.C. It can be seen throughout attitudes, values, uses and practices in both individuals and the whole regulatory organization. One among all the regulatory tools commonly used by regulators to promote and evaluate the commitment of the licensees with safety culture as a whole involves organizational factors and particular attention is directed to the operating organization. This entailed a wide range of activities, including all those related with management of safety performance. Operating Experience Feedback Programme as a tool to enhance safety operation is particularly useful for regulators in the evaluation of the role of S.C. in operating organization. Safety Culture is recognized as a subset of the wider Organizational Culture. Practices that improve organizational effectiveness can also contribute to enhance safety. An effective event investigation methodology is a specific practice, which contributes to a healthy Safety Culture. (author)

  7. The optimal solution of a non-convex state-dependent LQR problem and its applications.

    Directory of Open Access Journals (Sweden)

    Xudan Xu

    Full Text Available This paper studies a Non-convex State-dependent Linear Quadratic Regulator (NSLQR problem, in which the control penalty weighting matrix [Formula: see text] in the performance index is state-dependent. A necessary and sufficient condition for the optimal solution is established with a rigorous proof by Euler-Lagrange Equation. It is found that the optimal solution of the NSLQR problem can be obtained by solving a Pseudo-Differential-Riccati-Equation (PDRE simultaneously with the closed-loop system equation. A Comparison Theorem for the PDRE is given to facilitate solution methods for the PDRE. A linear time-variant system is employed as an example in simulation to verify the proposed optimal solution. As a non-trivial application, a goal pursuit process in psychology is modeled as a NSLQR problem and two typical goal pursuit behaviors found in human and animals are reproduced using different control weighting [Formula: see text]. It is found that these two behaviors save control energy and cause less stress over Conventional Control Behavior typified by the LQR control with a constant control weighting [Formula: see text], in situations where only the goal discrepancy at the terminal time is of concern, such as in Marathon races and target hitting missions.

  8. On distributive effects of optimal regulation for power grid expansion

    International Nuclear Information System (INIS)

    Herrera, Luis Ángel; Rosellón, Juan

    2014-01-01

    To date, the distributive implications of incentive regulation on electricity transmission networks have not been explicitly studied in the literature. More specifically, the parameters that a regulator might use to achieve distributive efficiency under price-cap regulation have not yet been identified. To discern these parameters is the motivation for the research presented in this paper. We study how different weight parameters affect the distributive characteristics of optimal price-cap incentive regulation for electricity transmission. We find that a regulator's use of ideal (Laspeyres) weights tends to be more beneficial for the Transco (consumers) than for consumers (the Transco). - Highlights: • Distributive implications of incentive regulation on transmission networks have not been studied in the literature. • The parameters that a regulator might use to achieve distributive efficiency have so far not been explicitly analyzed. • Analyze how different weights affect the distributive characteristics of price-cap regulation in electricity transmission. • Results: ideal (Laspeyres) weights tend to be more beneficial for the Transco (consumers) than for consumers (the Transco)

  9. Effects of different feedback types on information integration in repeated monetary gambles

    Directory of Open Access Journals (Sweden)

    Peter eHaffke

    2015-01-01

    Full Text Available Most models of risky decision making assume that all relevant information is taken into account (e.g., Kahneman & Tversky, 1979; von Neumann & Morgenstern, 1944. However, there are also some models supposing that only part of the information is considered (e.g., Brandstätter, Gigerenzer, & Hertwig, 2006; Gigerenzer & Gaissmaier, 2011. To further investigate the amount of information that is usually used for decision making, and how the use depends on feedback, we conducted a series of three experiments in which participants choose between two lotteries and where no feedback, outcome feedback, and error feedback was provided, respectively. The result show that without feedback participants mostly chose the lottery with the higher winning probability, and largely ignored the potential gains. The same result occurred when the outcome of each decision was fed back. Only after presenting error feedback (i.e., signaling whether a choice was optimal or not, participants considered probabilities as well as gains, resulting in more optimal choices. We propose that outcome feedback was ineffective, because of its probabilistic and ambiguous nature. Participants improve information integration only if provided with a consistent and deterministic signal such as error feedback.

  10. Analytic modeling of the feedback stabilization of resistive wall modes

    International Nuclear Information System (INIS)

    Pustovitov, Vladimir D.

    2003-01-01

    Feedback suppression of resistive wall modes (RWM) is studied analytically using a model based on a standard cylindrical approximation. Optimal choice of the input signal for the feedback, effects related to the geometry of the feedback active coils, RWM suppression in a configuration with ITER-like double wall, are considered here. The widespread opinion that the feedback with poloidal sensors is better than that with radial sensors is discussed. It is shown that for an ideal feedback system the best input signal would be a combination of radial and poloidal perturbations measured inside the vessel. (author)

  11. THEORETICAL ASPECTS OF STATE REGULATION OF NATIONAL MACROECONOMIC ENVIRONMENT

    Directory of Open Access Journals (Sweden)

    Yevgen Maslennikov

    2017-09-01

    Full Text Available The question of the economic role of the state was put up for a long time and until now every state solves this problem in different ways and only for itself, on the basis of the accumulated experience taking into account its customs and traditions. The objective need to include the state in the economic process is determined by such factors as: the need to ensure public reproduction on an extended scale, ensuring the long-term interests of the population, maintaining the balance of socio-economic interests of different population groups in the country, ensuring the unity and integrity of the country's territorial space. For this reason, the purpose of the paper is to examine the main theoretical aspects of state regulation of the economy in historical retrospect and at the present stage of the development of society. Methodology. Methodological and informational basis of the investigation are scientific articles, materials of periodicals, resources of the Internet. To achieve the goal set, the following general scientific and special methods were used: morphological analysis, system and structural-logical analysis, formalization, analogy, comparison and integration, tabular method. Results. As a result of the research, scientific and theoretical grounds for state regulation of national macroeconomic environment were presented; forms and methods of state regulation, programming as a form of perspective state regulation and principles of economic planning were considered in more detail. Practical implications. The considered forms of state regulation are relevant in the current conditions of management and can be applied by states in accordance with the level of economic development. Value/originality. The authors presented innovative forms of state regulation methods, and analyzed their effectiveness.

  12. A modular positive feedback-based gene amplifier

    Directory of Open Access Journals (Sweden)

    Bhalerao Kaustubh D

    2010-02-01

    Full Text Available Abstract Background Positive feedback is a common mechanism used in the regulation of many gene circuits as it can amplify the response to inducers and also generate binary outputs and hysteresis. In the context of electrical circuit design, positive feedback is often considered in the design of amplifiers. Similar approaches, therefore, may be used for the design of amplifiers in synthetic gene circuits with applications, for example, in cell-based sensors. Results We developed a modular positive feedback circuit that can function as a genetic signal amplifier, heightening the sensitivity to inducer signals as well as increasing maximum expression levels without the need for an external cofactor. The design utilizes a constitutively active, autoinducer-independent variant of the quorum-sensing regulator LuxR. We experimentally tested the ability of the positive feedback module to separately amplify the output of a one-component tetracycline sensor and a two-component aspartate sensor. In each case, the positive feedback module amplified the response to the respective inducers, both with regards to the dynamic range and sensitivity. Conclusions The advantage of our design is that the actual feedback mechanism depends only on a single gene and does not require any other modulation. Furthermore, this circuit can amplify any transcriptional signal, not just one encoded within the circuit or tuned by an external inducer. As our design is modular, it can potentially be used as a component in the design of more complex synthetic gene circuits.

  13. Robust Path Planning and Feedback Design Under Stochastic Uncertainty

    Science.gov (United States)

    Blackmore, Lars

    2008-01-01

    Autonomous vehicles require optimal path planning algorithms to achieve mission goals while avoiding obstacles and being robust to uncertainties. The uncertainties arise from exogenous disturbances, modeling errors, and sensor noise, which can be characterized via stochastic models. Previous work defined a notion of robustness in a stochastic setting by using the concept of chance constraints. This requires that mission constraint violation can occur with a probability less than a prescribed value.In this paper we describe a novel method for optimal chance constrained path planning with feedback design. The approach optimizes both the reference trajectory to be followed and the feedback controller used to reject uncertainty. Our method extends recent results in constrained control synthesis based on convex optimization to solve control problems with nonconvex constraints. This extension is essential for path planning problems, which inherently have nonconvex obstacle avoidance constraints. Unlike previous approaches to chance constrained path planning, the new approach optimizes the feedback gain as wellas the reference trajectory.The key idea is to couple a fast, nonconvex solver that does not take into account uncertainty, with existing robust approaches that apply only to convex feasible regions. By alternating between robust and nonrobust solutions, the new algorithm guarantees convergence to a global optimum. We apply the new method to an unmanned aircraft and show simulation results that demonstrate the efficacy of the approach.

  14. 27 CFR 479.52 - State regulations.

    Science.gov (United States)

    2010-04-01

    ... EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION MACHINE GUNS, DESTRUCTIVE DEVICES, AND CERTAIN OTHER FIREARMS Special (Occupational) Taxes Application of State Laws § 479.52 State regulations. Special tax stamps are merely receipts for the tax. Payment of tax under Federal law confers no privilege...

  15. Building robust functionality in synthetic circuits using engineered feedback regulation.

    Science.gov (United States)

    Chen, Susan; Harrigan, Patrick; Heineike, Benjamin; Stewart-Ornstein, Jacob; El-Samad, Hana

    2013-08-01

    The ability to engineer novel functionality within cells, to quantitatively control cellular circuits, and to manipulate the behaviors of populations, has many important applications in biotechnology and biomedicine. These applications are only beginning to be explored. In this review, we advocate the use of feedback control as an essential strategy for the engineering of robust homeostatic control of biological circuits and cellular populations. We also describe recent works where feedback control, implemented in silico or with biological components, was successfully employed for this purpose. Copyright © 2013 Elsevier Ltd. All rights reserved.

  16. Evaluation of multimodal feedback effects on improving rowing competencies

    Directory of Open Access Journals (Sweden)

    Korman Maria

    2011-12-01

    Full Text Available This study focused on the selection and preliminary evaluation of different types of modal and information feedback in virtual environment to facilitate acquisition and transfer of a complex motor-cognitive skill of rowing. Specifically, we addressed the effectiveness of immediate information feedback provided visually as compared to sensory haptic feedback on the improvement in hands kinematics and changes in cognitive load during the course of learning the basic rowing technique. Several pilot experiments described in this report lead to the evaluation and optimization of the training protocol, to enhance facilitatory effects of adding visual and haptic feedback during training.

  17. The effect of the nonhuman external regulator’s answer-until-correct (AUC) versus knowledge-of-result (KR) task feedback on children’s behavioral regulation during learning tasks

    NARCIS (Netherlands)

    Agina, Adel Masaud; Agina, Adel M.; Kommers, Petrus A.M.; Steehouder, M.F.

    2011-01-01

    The present study was conducted to shed a new light on the nonhuman’s external regulation effect on children’s behavioral regulation through investigating the effect of the computer’s task feedback answer-until-correct (AUC) versus knowledge-of-result (KR) with 40 preschool children (boys/girls)

  18. Natural equilibria in steady-state neutron diffusion with temperature feedback

    International Nuclear Information System (INIS)

    Pounders, J. M.; Ingram, R.

    2013-01-01

    The critical diffusion equation with feedback is investigated within the context of steady-state multiphysics. It is proposed that for critical configurations there is no need to include the multiplication factor k in the formulation of the diffusion equation. This is notable because exclusion of k from the coupled system of equations precludes the mathematically tenuous notion of a nonlinear eigenvalue problem. On the other hand, it is shown that if the factor k is retained in the diffusion equation, as is currently common practice, then the resulting problem is equivalent to the constrained minimization of a functional representing the critical equilibrium of neutron and temperature distributions. The unconstrained solution corresponding to k = 1 represents the natural equilibrium of a critical system at steady-state. Computational methods for solving the constrained problem (with k) are briefly reviewed from the literature and a method for the unconstrained problem (without k) is outlined. A numerical example is studied to examine the effects of the constraint in the nonlinear system. (authors)

  19. Quasideterministic generation of maximally entangled states of two mesoscopic atomic ensembles by adiabatic quantum feedback

    International Nuclear Information System (INIS)

    Di Lisi, Antonio; De Siena, Silvio; Illuminati, Fabrizio; Vitali, David

    2005-01-01

    We introduce an efficient, quasideterministic scheme to generate maximally entangled states of two atomic ensembles. The scheme is based on quantum nondemolition measurements of total atomic populations and on adiabatic quantum feedback conditioned by the measurements outputs. The high efficiency of the scheme is tested and confirmed numerically for ideal photodetection as well as in the presence of losses

  20. When more is less: Feedback effects in perceptual category learning ☆

    Science.gov (United States)

    Maddox, W. Todd; Love, Bradley C.; Glass, Brian D.; Filoteo, J. Vincent

    2008-01-01

    Rule-based and information-integration category learning were compared under minimal and full feedback conditions. Rule-based category structures are those for which the optimal rule is verbalizable. Information-integration category structures are those for which the optimal rule is not verbalizable. With minimal feedback subjects are told whether their response was correct or incorrect, but are not informed of the correct category assignment. With full feedback subjects are informed of the correctness of their response and are also informed of the correct category assignment. An examination of the distinct neural circuits that subserve rule-based and information-integration category learning leads to the counterintuitive prediction that full feedback should facilitate rule-based learning but should also hinder information-integration learning. This prediction was supported in the experiment reported below. The implications of these results for theories of learning are discussed. PMID:18455155

  1. Evidence for dynamic network regulation of Drosophila photoreceptor function from mutants lacking the neurotransmitter histamine

    Directory of Open Access Journals (Sweden)

    An eDau

    2016-03-01

    Full Text Available Synaptic feedback from interneurons to photoreceptors can help to optimize visual information flow by balancing its allocation on retinal pathways under changing light conditions. But little is known about how this critical network operation is regulated dynamically. Here, we investigate this question by comparing signaling properties and performance of wild-type Drosophila R1-R6 photoreceptors to those of the hdcJK910 mutant, which lacks the neurotransmitter histamine and therefore cannot transmit information to interneurons. Recordings show that hdcJK910 photoreceptors sample similar amounts of information from naturalistic stimulation to wild-type photoreceptors, but this information is packaged in smaller responses, especially under bright illumination. Analyses reveal how these altered dynamics primarily resulted from network overload that affected hdcJK910 photoreceptors in two ways. First, the missing inhibitory histamine input to interneurons almost certainly depolarized them irrevocably, which in turn increased their excitatory feedback to hdcJK910 R1-R6s. This tonic excitation depolarized the photoreceptors to artificially high potentials, reducing their operational range. Second, rescuing histamine input to interneurons in hdcJK910 mutant also restored their normal phasic feedback modulation to R1-R6s, causing photoreceptor output to accentuate dynamic intensity differences at bright illumination, similar to the wild-type. These results provide mechanistic explanations of how synaptic feedback connections optimize information packaging in photoreceptor output and novel insight into the operation and design of dynamic network regulation of sensory neurons.

  2. STATE REGULATION OF FRANCHISING IN THE EU MEMBER COUNTRIES

    OpenAIRE

    Solomiya Ohinok

    2015-01-01

    In despite of extensive research of franchising in the scientific community, there are a lot of unresolved issues relating to franchising, in particular its regulation at the national level and at the level of the European Union that is why the purpose of the paper is to summarise and present the difference between state regulation of franchising in the EU member states and to research the basic principles of state regulation of franchising in the EU also to analyze legislation of the franchi...

  3. Neural Feedback Scheduling of Real-Time Control Tasks

    OpenAIRE

    Xia, Feng; Tian, Yu-Chu; Sun, Youxian; Dong, Jinxiang

    2008-01-01

    Many embedded real-time control systems suffer from resource constraints and dynamic workload variations. Although optimal feedback scheduling schemes are in principle capable of maximizing the overall control performance of multitasking control systems, most of them induce excessively large computational overheads associated with the mathematical optimization routines involved and hence are not directly applicable to practical systems. To optimize the overall control performance while minimi...

  4. An integrated approach for optimal frequency regulation service procurement in India

    International Nuclear Information System (INIS)

    Parida, S.K.; Singh, S.N.; Srivastava, S.C.

    2009-01-01

    Ancillary services (AS) management has become an important issue to be addressed in the Indian power system after adaption of the restructuring and unbundling processes following the enactment of Indian Electricity Act 2003. In an electricity market, frequency regulation is one of the ancillary services, which must be procured by the system operator (SO) from the market participants by some regulatory mechanism or using market-based approaches. It is important for the SO to optimally procure this service from the AS market. In this paper, an approach for determining the optimal frequency regulation service procurement has been proposed for equitable payment to generators and recovery from the customers. The effectiveness of the proposed method has been demonstrated on a practical Northern Regional Electricity Board (NREB) system of India. (author)

  5. Fractional-Order Control of a Nonlinear Time-Delay System: Case Study in Oxygen Regulation in the Heart-Lung Machine

    Directory of Open Access Journals (Sweden)

    S. J. Sadati

    2012-01-01

    Full Text Available A fractional-order controller will be proposed to regulate the inlet oxygen into the heart-lung machine. An analytical approach will be explained to satisfy some requirements together with practical implementation of some restrictions for the first time. Primarily a nonlinear single-input single-output (SISO time-delay model which was obtained previously in the literature is introduced for the oxygen generation process in the heart-lung machine system and we will complete it by adding some new states to control it. Thereafter, the system is linearized using the state feedback linearization approach to find a third-order time-delay dynamics. Consequently classical PID and fractional order controllers are gained to assess the quality of the proposed technique. A set of optimal parameters of those controllers are achieved through the genetic algorithm optimization procedure through minimizing a cost function. Our design method focuses on minimizing some famous performance criterions such as IAE, ISE, and ITSE. In the genetic algorithm, the controller parameters are chosen as a random population. The best relevant values are achieved by reducing the cost function. A time-domain simulation signifies the performance of controller with respect to a traditional optimized PID controller.

  6. Application of Feedback System Control Optimization Technique in Combined Use of Dual Antiplatelet Therapy and Herbal Medicines

    Directory of Open Access Journals (Sweden)

    Wang Liu

    2018-05-01

    Full Text Available Aim: Combined use of herbal medicines in patients underwent dual antiplatelet therapy (DAPT might cause bleeding or thrombosis because herbal medicines with anti-platelet activities may exhibit interactions with DAPT. In this study, we tried to use a feedback system control (FSC optimization technique to optimize dose strategy and clarify possible interactions in combined use of DAPT and herbal medicines.Methods: Herbal medicines with reported anti-platelet activities were selected by searching related references in Pubmed. Experimental anti-platelet activities of representative compounds originated from these herbal medicines were investigated using in vitro assay, namely ADP-induced aggregation of rat platelet-rich-plasma. FSC scheme hybridized artificial intelligence calculation and bench experiments to iteratively optimize 4-drug combination and 2-drug combination from these drug candidates.Results: Totally 68 herbal medicines were reported to have anti-platelet activities. In the present study, 7 representative compounds from these herbal medicines were selected to study combinatorial drug optimization together with DAPT, i.e., aspirin and ticagrelor. FSC technique first down-selected 9 drug candidates to the most significant 5 drugs. Then, FSC further secured 4 drugs in the optimal combination, including aspirin, ticagrelor, ferulic acid from DangGui, and forskolin from MaoHouQiaoRuiHua. Finally, FSC quantitatively estimated the possible interactions between aspirin:ticagrelor, aspirin:ferulic acid, ticagrelor:forskolin, and ferulic acid:forskolin. The estimation was further verified by experimentally determined Combination Index (CI values.Conclusion: Results of the present study suggested that FSC optimization technique could be used in optimization of anti-platelet drug combinations and might be helpful in designing personal anti-platelet therapy strategy. Furthermore, FSC analysis could also identify interactions between different

  7. Stable Single-Mode Operation of Distributed Feedback Quantum Cascade Laser by Optimized Reflectivity Facet Coatings

    Science.gov (United States)

    Wang, Dong-Bo; Zhang, Jin-Chuan; Cheng, Feng-Min; Zhao, Yue; Zhuo, Ning; Zhai, Shen-Qiang; Wang, Li-Jun; Liu, Jun-Qi; Liu, Shu-Man; Liu, Feng-Qi; Wang, Zhan-Guo

    2018-02-01

    In this work, quantum cascade lasers (QCLs) based on strain compensation combined with two-phonon resonance design are presented. Distributed feedback (DFB) laser emitting at 4.76 μm was fabricated through a standard buried first-order grating and buried heterostructure (BH) processing. Stable single-mode emission is achieved under all injection currents and temperature conditions without any mode hop by the optimized antireflection (AR) coating on the front facet. The AR coating consists of a double layer dielectric of Al2O3 and Ge. For a 2-mm laser cavity, the maximum output power of the AR-coated DFB-QCL was more than 170 mW at 20 °C with a high wall-plug efficiency (WPE) of 4.7% in a continuous-wave (CW) mode.

  8. State of bus safety in the U.S. : summary of federal and state regulations.

    Science.gov (United States)

    2014-06-01

    This report provides a comprehensive overview of transit bus safety regulations and standards developed by all 50 states, as well as : information on how state departments of transportation (DOT) regulate the maintenance or operation of transit/parat...

  9. Predictive Feedback and Feedforward Control for Systems with Unknown Disturbances

    Science.gov (United States)

    Juang, Jer-Nan; Eure, Kenneth W.

    1998-01-01

    Predictive feedback control has been successfully used in the regulation of plate vibrations when no reference signal is available for feedforward control. However, if a reference signal is available it may be used to enhance regulation by incorporating a feedforward path in the feedback controller. Such a controller is known as a hybrid controller. This paper presents the theory and implementation of the hybrid controller for general linear systems, in particular for structural vibration induced by acoustic noise. The generalized predictive control is extended to include a feedforward path in the multi-input multi-output case and implemented on a single-input single-output test plant to achieve plate vibration regulation. There are cases in acoustic-induce vibration where the disturbance signal is not available to be used by the hybrid controller, but a disturbance model is available. In this case the disturbance model may be used in the feedback controller to enhance performance. In practice, however, neither the disturbance signal nor the disturbance model is available. This paper presents the theory of identifying and incorporating the noise model into the feedback controller. Implementations are performed on a test plant and regulation improvements over the case where no noise model is used are demonstrated.

  10. Optimized chaotic Brillouin dynamic grating with filtered optical feedback.

    Science.gov (United States)

    Zhang, Jianzhong; Li, Zhuping; Wu, Yuan; Zhang, Mingjiang; Liu, Yi; Li, Mengwen

    2018-01-16

    Chaotic Brillouin dynamic gratings (BDGs) have special advantages such as the creation of single, permanent and localized BDG. However, the periodic signals induced by conventional optical feedback (COF) in chaotic semiconductor lasers can lead to the generation of spurious BDGs, which will limit the application of chaotic BDGs. In this paper, filtered optical feedback (FOF) is proposed to eliminate spurious BDGs. By controlling the spectral width of the optical filter and its detuning from the laser frequency, semiconductor lasers with FOF operate in the suppression region of the time-delay signature, and chaotic outputs serving as pump waves are then utilized to generate the chaotic BDG in a polarization maintaining fiber. Through comparative analysis of the COF and FOF schemes, it has been demonstrated that spurious BDGs are effectively eliminated and that the reflection characterization of the chaotic BDG is improved. The influence of FOF on the reflection and gain spectra of the chaotic BDG is analyzed as well.

  11. The construction of optimal stated choice experiments theory and methods

    CERN Document Server

    Street, Deborah J

    2007-01-01

    The most comprehensive and applied discussion of stated choice experiment constructions available The Construction of Optimal Stated Choice Experiments provides an accessible introduction to the construction methods needed to create the best possible designs for use in modeling decision-making. Many aspects of the design of a generic stated choice experiment are independent of its area of application, and until now there has been no single book describing these constructions. This book begins with a brief description of the various areas where stated choice experiments are applicable, including marketing and health economics, transportation, environmental resource economics, and public welfare analysis. The authors focus on recent research results on the construction of optimal and near-optimal choice experiments and conclude with guidelines and insight on how to properly implement these results. Features of the book include: Construction of generic stated choice experiments for the estimation of main effects...

  12. Discrete Optimal Multirate Techniques for Excitation Controller Design of a Synchronous Machine

    Directory of Open Access Journals (Sweden)

    D. I. Pappas

    2016-02-01

    Full Text Available An optimal control strategy based on Two-Point-Multirate Controllers (TPMRCs, is used to design a desirable excitation controller of a hydrogenerator system, in order to enhance its dynamic stability characteristics. In the TPMRCs based scheme, the control is constrained to a certain piecewise constant signal, while each of the controlled plant outputs is detected many times over a fundamental sampling period T0. On the basis on this strategy, the original problem is reduced to an associate discrete-time linear quadratic (LQ regulation problem for the performance index with cross product terms, for which a fictitious static state feedback controller is needed to be computed. Simulation results for the actual 117 MVA synchronous generator with conventional exciter supplying line to an infinite grid show the effectiveness of the proposed method which has a quite satisfactory performance.

  13. Performance investigation of stochastic resonance in bistable systems with time-delayed feedback and three types of asymmetries

    Science.gov (United States)

    Liu, Jian; Wang, Youguo

    2018-03-01

    The simultaneous influence of potential asymmetries and time-delayed feedback on stochastic resonance (SR) subject to both periodic force and additive Gaussian white noise is investigated by using two-state theory and small-delay approximation, where three types of asymmetries include well-depth, well-width, and both well-depth and well-width asymmetries, respectively. The asymmetric types and time-delayed feedback determine the behaviors of SR, especially output signal-to-noise ratio (SNR) peaks, optimal additive noise intensity and feedback intensity. Moreover, the largest SNR in asymmetric SR is found to be relatively larger than symmetric one in some cases, whereas in other cases the symmetric SR is superior to asymmetric one, which is of dependence on time delay and feedback intensity. In addition, the SR with well-width asymmetry can suppress stronger noise than that with well-depth asymmetry under the action of same time delay, which is beneficial to weak signal detection.

  14. State statutes and regulations on radioactive materials transportation

    International Nuclear Information System (INIS)

    Foster, B.

    1981-11-01

    The transport of radioactive material is controlled by numerous legislative and regulatory actions at the federal, state, and local levels. This document is a compilation of the state level laws and regulations. The collected material is abstracted and indexed by states. Each state section contains three divisions: (1) abstracts of major statutes, (2) legislative rules, and (3) photocopies of relevant paragraphs from the law or regulation. This document was prepared for use by individuals who are involved in the radioactive material transportation process. This document will not be updated. The legislative rules section contains the name of the state agency primarily responsible for monitoring the transport of radioactive materials

  15. Dynamic Output Feedback Robust MPC with Input Saturation Based on Zonotopic Set-Membership Estimation

    Directory of Open Access Journals (Sweden)

    Xubin Ping

    2016-01-01

    Full Text Available For quasi-linear parameter varying (quasi-LPV systems with bounded disturbance, a synthesis approach of dynamic output feedback robust model predictive control (OFRMPC with the consideration of input saturation is investigated. The saturated dynamic output feedback controller is represented by a convex hull involving the actual dynamic output controller and an introduced auxiliary controller. By taking both the actual output feedback controller and the auxiliary controller with a parameter-dependent form, the main optimization problem can be formulated as convex optimization. The consideration of input saturation in the main optimization problem reduces the conservatism of dynamic output feedback controller design. The estimation error set and bounded disturbance are represented by zonotopes and refreshed by zonotopic set-membership estimation. Compared with the previous results, the proposed algorithm can not only guarantee the recursive feasibility of the optimization problem, but also improve the control performance at the cost of higher computational burden. A nonlinear continuous stirred tank reactor (CSTR example is given to illustrate the effectiveness of the approach.

  16. Multi-objective optimization of linear multi-state multiple sliding window system

    International Nuclear Information System (INIS)

    Konak, Abdullah; Kulturel-Konak, Sadan; Levitin, Gregory

    2012-01-01

    This paper considers the optimal element sequencing in a linear multi-state multiple sliding window system that consists of n linearly ordered multi-state elements. Each multi-state element can have different states: from complete failure up to perfect functioning. A performance rate is associated with each state. The failure of type i in the system occurs if for any i (1≤i≤I) the cumulative performance of any r i consecutive elements is lower than w i . The element sequence strongly affects the probability of any type of system failure. The sequence that minimizes the probability of certain type of failure can provide high probability of other types of failures. Therefore the optimization problem for the multiple sliding window system is essentially multi-objective. The paper formulates and solves the multi-objective optimization problem for the multiple sliding window systems. A multi-objective Genetic Algorithm is used as the optimization engine. Illustrative examples are presented.

  17. Designing and Evaluating Tutoring Feedback Strategies for digital learning environments on the basis of the Interactive Tutoring Feedback Model

    Directory of Open Access Journals (Sweden)

    Susanne Narciss

    2013-06-01

    Full Text Available This paper describes the interactive tutoring feedback model (ITF-model; Narciss, 2006; 2008, and how it can be applied to the design and evaluation of feedback strategies for digital learning environments. The ITF-model conceptualizes formative tutoring feedback as a multidimensional instructional activity that aims at contributing to the regulation of a learning process in order to help learners acquire or improve the competencies needed to master learning tasks. It integrates findings from systems theory with recommendations of prior research on interactive instruction and elaborated feedback, on task analyses, on error analyses, and on tutoring techniques. Based on this multi-dimensional view of formative tutoring feedback methodological implications for designing and investigating multiple effects of feedback under multiple individual and situational conditions are described. Furthermore, the paper outlines how the implications of the ITF-model have been applied in several studies to the design and evaluation of tutoring feedback strategies for digital learning environments (e.g., Narciss, 2004; Narciss & Huth, 2006; Narciss, Schnaubert, Andres, Eichelmann, Goguadze, & Sosnovsky, 2013.

  18. Perioperative feedback in surgical training: A systematic review.

    Science.gov (United States)

    McKendy, Katherine M; Watanabe, Yusuke; Lee, Lawrence; Bilgic, Elif; Enani, Ghada; Feldman, Liane S; Fried, Gerald M; Vassiliou, Melina C

    2017-07-01

    Changes in surgical training have raised concerns about residents' operative exposure and preparedness for independent practice. One way of addressing this concern is by optimizing teaching and feedback in the operating room (OR). The objective of this study was to perform a systematic review on perioperative teaching and feedback. A systematic literature search identified articles from 1994 to 2014 that addressed teaching, feedback, guidance, or debriefing in the perioperative period. Data was extracted according to ENTREQ guidelines, and a qualitative analysis was performed. Thematic analysis of the 26 included studies identified four major topics. Observation of teaching behaviors in the OR described current teaching practices. Identification of effective teaching strategies analyzed teaching behaviors, differentiating positive and negative teaching strategies. Perceptions of teaching behaviors described resident and attending satisfaction with teaching in the OR. Finally models for delivering structured feedback cited examples of feedback strategies and measured their effectiveness. This study provides an overview of perioperative teaching and feedback for surgical trainees and identifies a need for improved quality and quantity of structured feedback. Copyright © 2016 Elsevier Inc. All rights reserved.

  19. State Feedback Decoupling with In-Loop Lead Compensator in Stand-Alone VSIs

    DEFF Research Database (Denmark)

    Federico, de Bosio; Pastorelli, Michele; de Sousa Ribeiro, Luiz Antonio

    2016-01-01

    The performance of current and voltage regulators during transients and steady-state is of primary concern for power converters intended for stand-alone applications. Dynamics performance and command tracking capability are enhanced by actively decoupling the controlled states variables. To further...... widen the current loop bandwidth while still preserving a well-damped system a lead compensator structure on the forward loop is proposed. A 3 kHz bandwidth with 0.707 damping factor is achieved for the inner current controller. Accordingly, also the voltage regulator bandwidth can be widen, thus...

  20. Information entropies in antikaon-nucleon scattering and optimal state analysis

    International Nuclear Information System (INIS)

    Ion, D.B.; Ion, M.L.; Petrascu, C.

    1998-01-01

    It is known that Jaynes interpreted the entropy as the expected self-information of a class of mutually exclusive and exhaustive events, while the probability is considered to be the rational degree of belief we assign to events based on available experimental evidence. The axiomatic derivation of Jaynes principle of maximum entropy as well as of the Kullback principle of minimum cross-entropy have been reported. Moreover, the optimal states in the Hilbert space of the scattering amplitude, which are analogous to the coherent states from the Hilbert space of the wave functions, were introduced and developed. The possibility that each optimal state possesses a specific minimum entropic uncertainty relation similar to that of the coherent states was recently conjectured. In fact, the (angle and angular momenta) information entropies, as well as the entropic angle-angular momentum uncertainty relations, in the hadron-hadron scattering, are introduced. The experimental information entropies for the pion-nucleon scattering are calculated by using the available phase shift analyses. These results are compared with the information entropies of the optimal states. Then, the optimal state dominance in the pion-nucleon scattering is systematically observed for all P LAB = 0.02 - 10 GeV/c. Also, it is shown that the angle-angular momentum entropic uncertainty relations are satisfied with high accuracy by all the experimental information entropies. In this paper the (angle and angular momentum) information entropies of hadron-hadron scattering are experimentally investigated by using the antikaon-nucleon phase shift analysis. Then, it is shown that the experimental entropies are in agreement with the informational entropies of optimal states. The results obtained in this paper can be explained not only by the presence of an optimal background which accompanied the production of the elementary resonances but also by the presence of the optimal resonances. On the other hand

  1. Theoretical study on a multivariate feedback control of a sodium-heated steam generator

    International Nuclear Information System (INIS)

    Takahashi, R.; Maruyama, Y.; Oikawa, T.

    1984-01-01

    This paper applies the connection of a multivariate feedback controller with a state estimator to a 1-MW sodium-heated steam generator for LMFBR theoretically, to obtain a control strategy which emphasizes, from the view point of safety and availability of the FBR plant, that a superheat of 30 0 C should be required for the evaporator steam. This involves a trial to study the feasibility for the estimation of such an inaccessible variable as the dry-out location of tubes and utilize the state estimate to design a feedback controller of steam generators. The Kalman filter tested was found to generate reasonable estimates of the transient process variables of the steam generator and can provide a major advantage of regulating steam condition of the system even in the presence of contamination by a rather high level of measurement noise in the view point of economic uses of micro- and/or minicomputers. (orig.)

  2. Comment on "Synchronization of chaotic systems with delay using intermittent linear state feedback" [Chaos 18, 033122 (2008)].

    Science.gov (United States)

    Zhang, Yinping; Wang, Qing-Guo

    2008-12-01

    In the referenced paper, there is technical carelessness in the third lemma and in the main result. Hence, it is a possible failure when the result is used to design the intermittent linear state feedback controller for exponential synchronization of two chaotic delayed systems.

  3. 78 FR 13057 - Agency Information Collection Activities; Information Collection; IT Dashboard Feedback Mechanism

    Science.gov (United States)

    2013-02-26

    ... Information Collection Activities; Information Collection; IT Dashboard Feedback Mechanism AGENCY: Office of... previously approved information collection requirement regarding IT Dashboard Feedback Mechanism. DATES... Collection 3090- 0285, IT Dashboard Feedback Mechanism, by any of the following methods: Regulations.gov...

  4. Regulation of Ca2+ release from mitochondria by the oxidation-reduction state of pyridine nucleotides

    Science.gov (United States)

    Lehninger, Albert L.; Vercesi, Anibal; Bababunmi, Enitan A.

    1978-01-01

    Mitochondria from normal rat liver and heart, and also Ehrlich tumor cells, respiring on succinate as energy source in the presence of rotenone (to prevent net electron flow to oxygen from the endogenous pyridine nucleotides), rapidly take up Ca2+ and retain it so long as the pyridine nucleotides are kept in the reduced state. When acetoacetate is added to bring the pyridine nucleotides into a more oxidized state, Ca2+ is released to the medium. A subsequent addition of a reductant of the pyridine nucleotides such as β-hydroxybutyrate, glutamate, or isocitrate causes reuptake of the released Ca2+. Successive cycles of Ca2+ release and uptake can be induced by shifting the redox state of the pyridine nucleotides to more oxidized and more reduced states, respectively. Similar observations were made when succinate oxidation was replaced as energy source by ascorbate oxidation or by the hydrolysis of ATP. These and other observations form the basis of a hypothesis for feedback regulation of Ca2+-dependent substrate- or energy-mobilizing enzymatic reactions by the uptake or release of mitochondrial Ca2+, mediated by the cytosolic phosphate potential and the ATP-dependent reduction of mitochondrial pyridine nucleotides by reversal of electron transport. Images PMID:25436

  5. Feedback regulation of bile acid synthesis in human liver: Importance of HNF-4α for regulation of CYP7A1

    International Nuclear Information System (INIS)

    Abrahamsson, Anna; Gustafsson, Ulf; Ellis, Ewa; Nilsson, Lisa-Mari; Sahlin, Staffan; Bjoerkhem, Ingemar; Einarsson, Curt

    2005-01-01

    A great number of nuclear factors are involved in the negative feedback mechanism regulating bile acid synthesis. There are two major ways for the negative feedback to effect the synthesis; the SHP-dependent, involving FXR, and the SHP-independent way, affecting HNF-4α. We studied 23 patients with gallstone disease. Eight patients were treated with chenodeoxycholic acid, 7 with cholestyramine prior to operation, and 8 served as controls. Liver biopsies were analyzed with Real-time-PCR. In the cholestyramine-treated group mRNA levels of CYP7A1 were increased about 10-fold. Treatment with CDCA decreased the mRNA levels of CYP7A1 by about 70%. The mRNA levels of CYP8B1, CYP27A1, and CYP7B1 were not significantly altered in the treated groups. The analysis of mRNA levels for HNF-4α showed 64% higher levels in the cholestyramine-treated group compared to the controls. These levels showed positive and highly significant correlation to the levels of mRNA of CYP7A1 when studied in all three groups together. FXR, SHP, and LRH-1/FTF were not significantly affected by the different treatments. Our results indicate that when bile acid synthesis is upregulated by cholestyramine treatment the SHP-independent pathway for controlling CYP7A1 transcription dominates over the SHP-dependent pathway

  6. Feed Forward Neural Network and Optimal Control Problem with Control and State Constraints

    Science.gov (United States)

    Kmet', Tibor; Kmet'ová, Mária

    2009-09-01

    A feed forward neural network based optimal control synthesis is presented for solving optimal control problems with control and state constraints. The paper extends adaptive critic neural network architecture proposed by [5] to the optimal control problems with control and state constraints. The optimal control problem is transcribed into a nonlinear programming problem which is implemented with adaptive critic neural network. The proposed simulation method is illustrated by the optimal control problem of nitrogen transformation cycle model. Results show that adaptive critic based systematic approach holds promise for obtaining the optimal control with control and state constraints.

  7. A State-by-State Assessment of Food Service Regulations for Prevention of Norovirus Outbreaks.

    Science.gov (United States)

    Kambhampati, Anita; Shioda, Kayoko; Gould, L Hannah; Sharp, Donald; Brown, Laura G; Parashar, Umesh D; Hall, Aron J

    2016-09-01

    Noroviruses are the leading cause of foodborne disease in the United States. Foodborne transmission of norovirus is often associated with contamination of food during preparation by an infected food worker. The U.S. Food and Drug Administration's Food Code provides model food safety regulations for preventing transmission of foodborne disease in restaurants; however, adoption of specific provisions is at the discretion of state and local governments. We analyzed the food service regulations of all 50 states and the District of Columbia (i.e., 51 states) to describe differences in adoption of norovirus-related Food Code provisions into state food service regulations. We then assessed potential correlations between adoption of these regulations and characteristics of foodborne norovirus outbreaks reported to the National Outbreak Reporting System from 2009 through 2014. Of the 51 states assessed, all (100%) required food workers to wash their hands, and 39 (76%) prohibited bare-hand contact with ready-to-eat food. Thirty states (59%) required exclusion of staff with vomiting and diarrhea until 24 h after cessation of symptoms. Provisions requiring a certified food protection manager (CFPM) and a response plan for contamination events (i.e., vomiting) were least commonly adopted; 26 states (51%) required a CFPM, and 8 (16%) required a response plan. Although not statistically significant, states that adopted the provisions prohibiting bare-hand contact (0.45 versus 0.74, P =0.07), requiring a CFPM (0.38 versus 0.75, P =0.09), and excluding ill staff for ≥24 h after symptom resolution (0.44 versus 0.73, P =0.24) each reported fewer foodborne norovirus outbreaks per million person-years than did those states without these provisions. Adoption and compliance with federal recommended food service regulations may decrease the incidence of foodborne norovirus outbreaks.

  8. Self-regulated growth of supermassive black holes by a dual jet-heating active galactic nucleus feedback mechanism: methods, tests and implications for cosmological simulations

    Science.gov (United States)

    Dubois, Yohan; Devriendt, Julien; Slyz, Adrianne; Teyssier, Romain

    2012-03-01

    We develop a subgrid model for the growth of supermassive black holes (BHs) and their associated active galactic nucleus (AGN) feedback in hydrodynamical cosmological simulations. This model transposes previous attempts to describe BH accretion and AGN feedback with the smoothed particle hydrodynamics (SPH) technique to the adaptive mesh refinement framework. It also furthers their development by implementing a new jet-like outflow treatment of the AGN feedback which we combine with the heating mode traditionally used in the SPH approach. Thus, our approach allows one to test the robustness of the conclusions derived from simulating the impact of self-regulated AGN feedback on galaxy formation vis-à-vis the numerical method. Assuming that BHs are created in the early stages of galaxy formation, they grow by mergers and accretion of gas at a Eddington-limited Bondi accretion rate. However this growth is regulated by AGN feedback which we model using two different modes: a quasar-heating mode when accretion rates on to the BHs are comparable to the Eddington rate, and a radio-jet mode at lower accretion rates which not only deposits energy, but also deposits mass and momentum on the grid. In other words, our feedback model deposits energy as a succession of thermal bursts and jet outflows depending on the properties of the gas surrounding the BHs. We assess the plausibility of such a model by comparing our results to observational measurements of the co-evolution of BHs and their host galaxy properties, and check their robustness with respect to numerical resolution. We show that AGN feedback must be a crucial physical ingredient for the formation of massive galaxies as it appears to be able to efficiently prevent the accumulation of and/or expel cold gas out of haloes/galaxies and significantly suppress star formation. Our model predicts that the relationship between BHs and their host galaxy mass evolves as a function of redshift, because of the vigorous accretion

  9. MicroRNA miR-308 regulates dMyc through a negative feedback loop in Drosophila

    Directory of Open Access Journals (Sweden)

    Kaveh Daneshvar

    2012-10-01

    The abundance of Myc protein must be exquisitely controlled to avoid growth abnormalities caused by too much or too little Myc. An intriguing mode of regulation exists in which Myc protein itself leads to reduction in its abundance. We show here that dMyc binds to the miR-308 locus and increases its expression. Using our gain-of-function approach, we show that an increase in miR-308 causes a destabilization of dMyc mRNA and reduced dMyc protein levels. In vivo knockdown of miR-308 confirmed the regulation of dMyc levels in embryos. This regulatory loop is crucial for maintaining appropriate dMyc levels and normal development. Perturbation of the loop, either by elevated miR-308 or elevated dMyc, caused lethality. Combining elevated levels of both, therefore restoring balance between miR-308 and dMyc levels, resulted in lower apoptotic activity and suppression of lethality. These results reveal a sensitive feedback mechanism that is crucial to prevent the pathologies caused by abnormal levels of dMyc.

  10. Time-delayed feedback control of coherence resonance chimeras

    Science.gov (United States)

    Zakharova, Anna; Semenova, Nadezhda; Anishchenko, Vadim; Schöll, Eckehard

    2017-11-01

    Using the model of a FitzHugh-Nagumo system in the excitable regime, we investigate the influence of time-delayed feedback on noise-induced chimera states in a network with nonlocal coupling, i.e., coherence resonance chimeras. It is shown that time-delayed feedback allows for the control of the range of parameter values where these chimera states occur. Moreover, for the feedback delay close to the intrinsic period of the system, we find a novel regime which we call period-two coherence resonance chimera.

  11. Franchise Values, Regulatory Monitoring, and Capital Requirements in Optimal Bank Regulation

    DEFF Research Database (Denmark)

    Andersen, Thomas Barnebeck; Harr, Thomas

    2008-01-01

    This paper demonstrates that financial deregulation is likely to make standard prudential regulatory instruments less effective in curbing excessive risk-taking incentives among banks. This has interesting implications for optimal bank regulation. When there is an increase in competition, the opt...

  12. Performance enhancement of microbial fuel cell by applying transient-state regulation

    International Nuclear Information System (INIS)

    Liang, Peng; Zhang, Changyong; Jiang, Yong; Bian, Yanhong; Zhang, Helan; Sun, Xueliang; Yang, Xufei; Zhang, Xiaoyuan; Huang, Xia

    2017-01-01

    Highlights: • MFC was operated with transient-state regulation to enhance its performance. • Effects of the TSR parameters on MFC performance were thoroughly investigated. • Long-term operation of MFC in TSR mode allowed 32.7% higher power production. • Anode capacitance helped reduce the MFC’s internal impedance in the TSR mode. - Abstract: A binder-free, pseudocapacitive anode was fabricated by coating reduced graphene oxide (rGO) and manganese oxide (MnO_2) nanoparticles on stainless steel fibre felt (SS). Microbial fuel cell (MFC) equipped with this novel anode yielded a maximum power density of 1045 mW m"−"2, 20 times higher than that of a similar MFC with a bare SS anode (46 mW m"−"2). Transient-state regulation (TSR) was implemented to further improve the MFC’s power generation. The optimal TSR duty cycle ranged from 67% to 95%, and the MFC’s power density increased with TSR frequency. A maximum power density output of 1238 mW m"−"2 was achieved at the TSR duty cycle of 75% and the frequency of 1 Hz, 18.4% greater than that obtained from the steady state operation. The TSR mode delivered better MFC performance especially when the external resistance was small. Long-term operation tests revealed that the current density and power density yielded in the TSR mode were on average 15.0% and 32.7% greater than those in the steady state mode, respectively. The TSR mode was believed to reduce the internal resistance of the MFC while enhance substrate mass transfer and electron transfer within the anode matrix, thereby improving the MFC performance.

  13. Pareto design of state feedback tracking control of a biped robot via multiobjective PSO in comparison with sigma method and genetic algorithms: modified NSGAII and MATLAB's toolbox.

    Science.gov (United States)

    Mahmoodabadi, M J; Taherkhorsandi, M; Bagheri, A

    2014-01-01

    An optimal robust state feedback tracking controller is introduced to control a biped robot. In the literature, the parameters of the controller are usually determined by a tedious trial and error process. To eliminate this process and design the parameters of the proposed controller, the multiobjective evolutionary algorithms, that is, the proposed method, modified NSGAII, Sigma method, and MATLAB's Toolbox MOGA, are employed in this study. Among the used evolutionary optimization algorithms to design the controller for biped robots, the proposed method operates better in the aspect of designing the controller since it provides ample opportunities for designers to choose the most appropriate point based upon the design criteria. Three points are chosen from the nondominated solutions of the obtained Pareto front based on two conflicting objective functions, that is, the normalized summation of angle errors and normalized summation of control effort. Obtained results elucidate the efficiency of the proposed controller in order to control a biped robot.

  14. Output-feedback control of combined sewer networks through receding horizon control with moving horizon estimation

    OpenAIRE

    Joseph-Duran, Bernat; Ocampo-Martinez, Carlos; Cembrano, Gabriela

    2015-01-01

    An output-feedback control strategy for pollution mitigation in combined sewer networks is presented. The proposed strategy provides means to apply model-based predictive control to large-scale sewer networks, in-spite of the lack of measurements at most of the network sewers. In previous works, the authors presented a hybrid linear control-oriented model for sewer networks together with the formulation of Optimal Control Problems (OCP) and State Estimation Problems (SEP). By iteratively solv...

  15. A study of the application of singular perturbation theory. [development of a real time algorithm for optimal three dimensional aircraft maneuvers

    Science.gov (United States)

    Mehra, R. K.; Washburn, R. B.; Sajan, S.; Carroll, J. V.

    1979-01-01

    A hierarchical real time algorithm for optimal three dimensional control of aircraft is described. Systematic methods are developed for real time computation of nonlinear feedback controls by means of singular perturbation theory. The results are applied to a six state, three control variable, point mass model of an F-4 aircraft. Nonlinear feedback laws are presented for computing the optimal control of throttle, bank angle, and angle of attack. Real Time capability is assessed on a TI 9900 microcomputer. The breakdown of the singular perturbation approximation near the terminal point is examined Continuation methods are examined to obtain exact optimal trajectories starting from the singular perturbation solutions.

  16. Optimal linear-quadratic control of coupled parabolic-hyperbolic PDEs

    Science.gov (United States)

    Aksikas, I.; Moghadam, A. Alizadeh; Forbes, J. F.

    2017-10-01

    This paper focuses on the optimal control design for a system of coupled parabolic-hypebolic partial differential equations by using the infinite-dimensional state-space description and the corresponding operator Riccati equation. Some dynamical properties of the coupled system of interest are analysed to guarantee the existence and uniqueness of the solution of the linear-quadratic (LQ)-optimal control problem. A state LQ-feedback operator is computed by solving the operator Riccati equation, which is converted into a set of algebraic and differential Riccati equations, thanks to the eigenvalues and the eigenvectors of the parabolic operator. The results are applied to a non-isothermal packed-bed catalytic reactor. The LQ-optimal controller designed in the early portion of the paper is implemented for the original nonlinear model. Numerical simulations are performed to show the controller performances.

  17. A rho scaffold integrates the secretory system with feedback mechanisms in regulation of auxin distribution.

    Directory of Open Access Journals (Sweden)

    Ora Hazak

    2010-01-01

    Full Text Available Development in multicellular organisms depends on the ability of individual cells to coordinate their behavior by means of small signaling molecules to form correctly patterned tissues. In plants, a unique mechanism of directional transport of the signaling molecule auxin between cells connects cell polarity and tissue patterning and thus is required for many aspects of plant development. Direction of auxin flow is determined by polar subcellular localization of PIN auxin efflux transporters. Dynamic PIN polar localization results from the constitutive endocytic cycling to and from the plasma membrane, but it is not well understood how this mechanism connects to regulators of cell polarity. The Rho family small GTPases ROPs/RACs are master regulators of cell polarity, however their role in regulating polar protein trafficking and polar auxin transport has not been established. Here, by analysis of mutants and transgenic plants, we show that the ROP interactor and polarity regulator scaffold protein ICR1 is required for recruitment of PIN proteins to the polar domains at the plasma membrane. icr1 mutant embryos and plants display an a array of severe developmental aberrations that are caused by compromised differential auxin distribution. ICR1 functions at the plasma membrane where it is required for exocytosis but does not recycle together with PINs. ICR1 expression is quickly induced by auxin but is suppressed at the positions of stable auxin maxima in the hypophysis and later in the embryonic and mature root meristems. Our results imply that ICR1 is part of an auxin regulated positive feedback loop realized by a unique integration of auxin-dependent transcriptional regulation into ROP-mediated modulation of cell polarity. Thus, ICR1 forms an auxin-modulated link between cell polarity, exocytosis, and auxin transport-dependent tissue patterning.

  18. Kinematic feedback control laws for generating natural arm movements

    International Nuclear Information System (INIS)

    Kim, Donghyun; Jang, Cheongjae; Park, Frank C

    2014-01-01

    We propose a stochastic optimal feedback control law for generating natural robot arm motions. Our approach, inspired by the minimum variance principle of Harris and Wolpert (1998 Nature 394 780–4) and the optimal feedback control principles put forth by Todorov and Jordan (2002 Nature Neurosci. 5 1226–35) for explaining human movements, differs in two crucial respects: (i) the endpoint variance is minimized in joint space rather than Cartesian hand space, and (ii) we ignore the dynamics and instead consider only the second-order differential kinematics. The feedback control law generating the motions can be straightforwardly obtained by backward integration of a set of ordinary differential equations; these equations are obtained exactly, without any linear–quadratic approximations. The only parameters to be determined a priori are the variance scale factors, and for both the two-DOF planar arm and the seven-DOF spatial arm, a table of values is constructed based on the given initial and final arm configurations; these values are determined via an optimal fitting procedure, and consistent with existing findings about neuromuscular motor noise levels of human arm muscles. Experiments conducted with a two-link planar arm and a seven-DOF spatial arm verify that the trajectories generated by our feedback control law closely resemble human arm motions, in the sense of producing nearly straight-line hand trajectories, having bell-shaped velocity profiles, and satisfying Fitts Law. (paper)

  19. Dynamic imperfections and optimized feedback design in the Compact Linear Collider main linac

    CERN Document Server

    Eliasson, Peder

    2008-01-01

    The Compact Linear Collider (CLIC) main linac is sensitive to dynamic imperfections such as element jitter, injected beam jitter, and ground motion. These effects cause emittance growth that, in case of ground motion, has to be counteracted by a trajectory feedback system. The feedback system itself will, due to jitter effects and imperfect beam position monitors (BPMs), indirectly cause emittance growth. Fast and accurate simulations of both the direct and indirect effects are desirable, but due to the many elements of the CLIC main linac, simulations may become very time consuming. In this paper, an efficient way of simulating linear (or nearly linear) dynamic effects is described. The method is also shown to facilitate the analytic determination of emittance growth caused by the different dynamic imperfections while using a trajectory feedback system. Emittance growth expressions are derived for quadrupole, accelerating structure, and beam jitter, for ground motion, and for noise in the feedback BPMs. Fina...

  20. Effects of Feedback Timing and Type on Learning ESL Grammar Rules

    Science.gov (United States)

    Lavolette, Elizabeth H. P.

    2014-01-01

    The optimal timing of feedback on formative assessments is an open question, with the cognitive processing window theory (Doughty, 2001) underlying the interaction approach suggesting that immediate feedback may be most beneficial for language acquisition (e.g., Gass, 2010; Polio, 2012) and two educational psychology hypotheses conversely…

  1. Competitive Electricity Market Regulation in the United States: A Primer

    Energy Technology Data Exchange (ETDEWEB)

    Flores-Espino, Francisco [National Renewable Energy Lab. (NREL), Golden, CO (United States); Tian, Tian [National Renewable Energy Lab. (NREL), Golden, CO (United States); Chernyakhovskiy, Ilya [National Renewable Energy Lab. (NREL), Golden, CO (United States); Chernyakhovskiy, Ilya [National Renewable Energy Lab. (NREL), Golden, CO (United States); Miller, Mackay [National Grid, Warwick (United Kingdom)

    2016-12-01

    The electricity system in the United States is a complex mechanism where different technologies, jurisdictions and regulatory designs interact. Today, two major models for electricity commercialization operate in the United States. One is the regulated monopoly model, in which vertically integrated electricity providers are regulated by state commissions. The other is the competitive model, in which power producers can openly access transmission infrastructure and participate in wholesale electricity markets. This paper describes the origins, evolution, and current status of the regulations that enable competitive markets in the United States.

  2. Regulations for radiochemical facilities in the United States

    International Nuclear Information System (INIS)

    Emeigh, Ch; Smith, B.; Williams, T

    1999-01-01

    Material control and accounting is implemented to provide assurance that physical protection measures have been effective, and in case they fail, to provide delayed detection of the loss. Regulations in the United States have been developed that include both performance and compliance requirements to provide a defence in depth approach addressing the unique characteristics of each facility. Regulations address administrative controls, material control and material accounting. Nuclear materials control and accounting plans are negotiated between regulatory agencies and facilities to develop a site-specific approach. An overview of the regulations and their implementation in the United State is provided [ru

  3. Feedback of operating experience in nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-06-01

    The feedback of operating experience of nuclear facilities to the designers, manufacturers, operators and regulators is one important means of maintaining and improving safety. The Atomic Energy Control Board`s Advisory Committee on Nuclear Safety examined the means for feedback currently being employed, how effective they are and what improvements are advisable. The review found that the need for feedback of operating experience is well recognized within those institutions contributing to the safety of CANDU power reactors, and that the existing procedures are generally effective. Some recommendations, however, are submitted for improvement in the process.

  4. Feedback of operating experience in nuclear power plants

    International Nuclear Information System (INIS)

    1995-06-01

    The feedback of operating experience of nuclear facilities to the designers, manufacturers, operators and regulators is one important means of maintaining and improving safety. The Atomic Energy Control Board's Advisory Committee on Nuclear Safety examined the means for feedback currently being employed, how effective they are and what improvements are advisable. The review found that the need for feedback of operating experience is well recognized within those institutions contributing to the safety of CANDU power reactors, and that the existing procedures are generally effective. Some recommendations, however, are submitted for improvement in the process

  5. Cultivating Engagement and Enjoyment in Exergames Using Feedback, Challenge, and Rewards.

    Science.gov (United States)

    Lyons, Elizabeth J

    2015-02-01

    This article reviews theoretical and empirical evidence related to three mechanisms for encouraging enjoyment during exergame play: Feedback, challenge, and rewards. A literature search and narrative review were conducted. Feedback is found in nearly all exergames, and richer, more in-depth feedback is associated with increased activity. Challenge is a vital component of any videogame, and exergames include physical as well as cognitive challenges. Flow states have traditionally been conceptualized as occurring when an optimal match between player skills and game challenge occurs. However, failure and retrial are necessary for feelings of overall satisfaction and fun, despite not necessarily being ideally fun or satisfying themselves. Rewards are a more complicated issue, with significant theoretical and empirical evidence suggesting positive and negative effects of reward systems. How rewards are integrated into the mechanics and storyline of the game likely impacts how they are perceived and, thus, their effectiveness. Finally, integration of these mechanisms into exergames requires specific attention to both cognitive and physical implementations. Movements that are not themselves enjoyable or engaging may lead to cheating and lower energy expenditure. Feedback, challenge, and rewards are promising mechanisms by which exergames could become more enjoyable. How these concepts are operationalized can affect physical and psychological reactions to exergames. Attention to these concepts in future exergame development and implementation would benefit theory, research, and practice.

  6. Coupling between feedback loops in autoregulatory networks affects bistability range, open-loop gain and switching times

    International Nuclear Information System (INIS)

    Tiwari, Abhinav; Igoshin, Oleg A

    2012-01-01

    Biochemical regulatory networks governing diverse cellular processes such as stress-response, differentiation and cell cycle often contain coupled feedback loops. We aim at understanding how features of feedback architecture, such as the number of loops, the sign of the loops and the type of their coupling, affect network dynamical performance. Specifically, we investigate how bistability range, maximum open-loop gain and switching times of a network with transcriptional positive feedback are affected by additive or multiplicative coupling with another positive- or negative-feedback loop. We show that a network's bistability range is positively correlated with its maximum open-loop gain and that both quantities depend on the sign of the feedback loops and the type of feedback coupling. Moreover, we find that the addition of positive feedback could decrease the bistability range if we control the basal level in the signal-response curves of the two systems. Furthermore, the addition of negative feedback has the capacity to increase the bistability range if its dissociation constant is much lower than that of the positive feedback. We also find that the addition of a positive feedback to a bistable network increases the robustness of its bistability range, whereas the addition of a negative feedback decreases it. Finally, we show that the switching time for a transition from a high to a low steady state increases with the effective fold change in gene regulation. In summary, we show that the effect of coupled feedback loops on the bistability range and switching times depends on the underlying mechanistic details. (paper)

  7. Optimal control of a CSTR process

    Directory of Open Access Journals (Sweden)

    A. Soukkou

    2008-12-01

    Full Text Available Designing an effective criterion and learning algorithm for find the best structure is a major problem in the control design process. In this paper, the fuzzy optimal control methodology is applied to the design of the feedback loops of an Exothermic Continuous Stirred Tank Reactor system. The objective of design process is to find an optimal structure/gains of the Robust and Optimal Takagi Sugeno Fuzzy Controller (ROFLC. The control signal thus obtained will minimize a performance index, which is a function of the tracking/regulating errors, the quantity of the energy of the control signal applied to the system, and the number of fuzzy rules. The genetic learning is proposed for constructing the ROFLC. The chromosome genes are arranged into two parts, the binary-coded part contains the control genes and the real-coded part contains the genes parameters representing the fuzzy knowledge base. The effectiveness of this chromosome formulation enables the fuzzy sets and rules to be optimally reduced. The performances of the ROFLC are compared to these found by the traditional PD controller with Genetic Optimization (PD_GO. Simulations demonstrate that the proposed ROFLC and PD_GO has successfully met the design specifications.

  8. VEGF selectively induces Down syndrome critical region 1 gene expression in endothelial cells: a mechanism for feedback regulation of angiogenesis?

    International Nuclear Information System (INIS)

    Yao, Y.-G; Duh, Elia J.

    2004-01-01

    The Down syndrome critical region 1 (DSCR1) gene (also known as MCIP1, Adapt78) encodes a regulatory protein that binds to calcineurin catalytic A subunit and acts as a regulator of the calcineurin-mediated signaling pathway. We show in this study that DSCR1 is greatly induced in endothelial cells in response to VEGF, TNF-α, and A23187 treatment, and that this up-regulation is inhibited by inhibitors of the calcineurin-NFAT (nuclear factor of activated T cells) signaling pathway as well as by PKC inhibition and a Ca 2+ chelator. We hypothesized that the up-regulation of DSCR1 gene expression in endothelial cells could act as an endogenous feedback inhibitor for angiogenesis by regulating the calcineurin-NFAT signaling pathway. Our transient transfection analyses confirm that the overexpression of DSCR1 abrogates the up-regulation of reporter gene expression driven by both the cyclooxygenase 2 and DSCR1 promoters in response to stimulators. Our results indicate that DSCR1 up-regulation may represent a potential molecular mechanism underlying the regulation of angiogenic genes activated by the calcineurin-NFAT signaling pathway in endothelial cells

  9. Generalized fast feedback system in the SLC

    International Nuclear Information System (INIS)

    Hendrickson, L.; Allison, S.; Gromme, T.; Himel, T.; Krauter, K.; Rouse, F.; Sass, R.; Shoaee, H.

    1991-11-01

    A generalized fast feedback system has been developed to stabilize beams at various locations in the SLC. The system is designed to perform measurements and change actuator settings to control beam states such as position, angle and energy on a pulse to pulse basis. The software design is based on the state space formalism of digital control theory. The system is database-driven, facilitating the addition of new loops without requiring additional software. A communications system, KISNet, provides fast communications links between microprocessors for feedback loops which involve multiple micros. Feedback loops have been installed in seventeen locations throughout the SLC and have proven to be invaluable in stabilizing the machine

  10. Optimal Control and Operation Strategy for Wind Turbines Contributing to Grid Primary Frequency Regulation

    Directory of Open Access Journals (Sweden)

    Mun-Kyeom Kim

    2017-09-01

    Full Text Available This study introduces a frequency regulation strategy to enable the participation of wind turbines with permanent magnet synchronous generators (PMSGs. The optimal strategy focuses on developing the frequency support capability of PMSGs connected to the power system. Active power control is performed using maximum power point tracking (MPPT and de-loaded control to supply the required power reserve following a disturbance. A kinetic energy (KE reserve control is developed to enhance the frequency regulation capability of wind turbines. The coordination with the de-loaded control prevents instability in the PMSG wind system due to excessive KE discharge. A KE optimization method that maximizes the sum of the KE reserves at wind farms is also adopted to determine the de-loaded power reference for each PMSG wind turbine using the particle swarm optimization (PSO algorithm. To validate the effectiveness of the proposed optimal control and operation strategy, three different case studies are conducted using the PSCAD/EMTDC simulation tool. The results demonstrate that the optimal strategy enhances the frequency support contribution from PMSG wind turbines.

  11. Chimeralike states in networks of bistable time-delayed feedback oscillators coupled via the mean field.

    Science.gov (United States)

    Ponomarenko, V I; Kulminskiy, D D; Prokhorov, M D

    2017-08-01

    We study the collective dynamics of oscillators in a network of identical bistable time-delayed feedback systems globally coupled via the mean field. The influence of delay and inertial properties of the mean field on the collective behavior of globally coupled oscillators is investigated. A variety of oscillation regimes in the network results from the presence of bistable states with substantially different frequencies in coupled oscillators. In the physical experiment and numerical simulation we demonstrate the existence of chimeralike states, in which some of the oscillators in the network exhibit synchronous oscillations, while all other oscillators remain asynchronous.

  12. Optimized entanglement witnesses for Dicke states

    Energy Technology Data Exchange (ETDEWEB)

    Bergmann, Marcel; Guehne, Otfried [Naturwissenschaftlich-Technische Fakultaet, Universitaet Siegen, Department Physik, Walter-Flex-Strasse 3, D-57068 Siegen (Germany)

    2013-07-01

    Quantum entanglement is an important resource for applications in quantum information processing like quantum teleportation and cryptography. Moreover, the number of particles that can be entangled experimentally using polarized photons or ion traps has been significantly enlarged. Therefore, criteria to decide the question whether a given multi-particle state is entangled or not have to be improved. Our approach to this problem uses the notion of PPT mixtures which form an approximation to the set of bi-separable states. With this method, entanglement witnesses can be obtained in a natural manner via linear semi-definite programming. In our contribution, we will present analytical results for entanglement witnesses for Dicke states. This allows to overcome the limitations of convex optimization.

  13. Optimal preventive maintenance and repair policies for multi-state systems

    International Nuclear Information System (INIS)

    Sheu, Shey-Huei; Chang, Chin-Chih; Chen, Yen-Luan; George Zhang, Zhe

    2015-01-01

    This paper studies the optimal preventive maintenance (PM) policies for multi-state systems. The scheduled PMs can be either imperfect or perfect type. The improved effective age is utilized to model the effect of an imperfect PM. The system is considered as in a failure state (unacceptable state) once its performance level falls below a given customer demand level. If the system fails before a scheduled PM, it is repaired and becomes operational again. We consider three types of major, minimal, and imperfect repair actions, respectively. The deterioration of the system is assumed to follow a non-homogeneous continuous time Markov process (NHCTMP) with finite state space. A recursive approach is proposed to efficiently compute the time-dependent distribution of the multi-state system. For each repair type, we find the optimal PM schedule that minimizes the average cost rate. The main implication of our results is that in determining the optimal scheduled PM, choosing the right repair type will significantly improve the efficiency of the system maintenance. Thus PM and repair decisions must be made jointly to achieve the best performance

  14. Non-equilibrium steady state of a driven levitated particle with feedback cooling

    International Nuclear Information System (INIS)

    Gieseler, Jan; Novotny, Lukas; Moritz, Clemens; Dellago, Christoph

    2015-01-01

    Laser trapped nanoparticles have been recently used as model systems to study fundamental relations holding far from equilibrium. Here we study a nanoscale silica sphere levitated by a laser in a low density gas. The center of mass motion of the particle is subjected, at the same time, to feedback cooling and a parametric modulation driving the system into a non-equilibrium steady state. Based on the Langevin equation of motion of the particle, we derive an analytical expression for the energy distribution of this steady state showing that the average and variance of the energy distribution can be controlled separately by appropriate choice of the friction, cooling and modulation parameters. Energy distributions determined in computer simulations and measured in a laboratory experiment agree well with the analytical predictions. We analyze the particle motion also in terms of the quadratures and find thermal squeezing depending on the degree of detuning. (paper)

  15. Qualitative and quantitative feedback in the context of competency-based education.

    Science.gov (United States)

    Tekian, Ara; Watling, Christopher J; Roberts, Trudie E; Steinert, Yvonne; Norcini, John

    2017-12-01

    Research indicates the importance and usefulness of feedback, yet with the shift of medical curricula toward competencies, feedback is not well understood in this context. This paper attempts to identify how feedback fits within a competency-based curriculum. After careful consideration of the literature, the following conclusions are drawn: (1) Because feedback is predicated on assessment, the assessment should be designed to optimize and prevent inaccuracies in feedback; (2) Giving qualitative feedback in the form of a conversation would lend credibility to the feedback, address emotional obstacles and create a context in which feedback is comfortable; (3) Quantitative feedback in the form of individualized data could fulfill the demand for more feedback, help students devise strategies on how to improve, allow students to compare themselves to their peers, recognizing that big data have limitations; and (4) Faculty development needs to incorporate and promote cultural and systems changes with regard to feedback. A better understanding of the role of feedback in competency-based education could result in more efficient learning for students.

  16. Factors influencing students' receptivity to formative feedback emerging from different assessment cultures

    NARCIS (Netherlands)

    Harrison, C.J.; Konings, K.D.; Dannefer, E.F.; Schuwirth, L.W.; Wass, V.; Vleuten, C.P.M. van der

    2016-01-01

    INTRODUCTION: Feedback after assessment is essential to support the development of optimal performance, but often fails to reach its potential. Although different assessment cultures have been proposed, the impact of these cultures on students' receptivity to feedback is unclear. This study aimed to

  17. Klystron equalization for RF feedback

    International Nuclear Information System (INIS)

    Corredoura, P.

    1993-01-01

    The next generation of colliding beam storage rings support higher luminosities by significantly increasing the number of bunches and decreasing the spacing between respective bunches. The heavy beam loading requires large RF cavity detuning which drives several lower coupled bunch modes very strongly. One technique which has proven to be very successful in reducing the coupled bunch mode driving impedance is RF feedback around the klystron-cavity combination. The gain and bandwidth of the feedback loop is limited by the group delay around the feedback loop. Existing klystrons on the world market have not been optimized for this application and contribute a large portion of the total loop group delay. This paper describes a technique to reduce klystron group delay by adding an equalizing filter to the klystron RF drive. Such a filter was built and tested on a 500 kill klystron as part of the on going PEP-II R ampersand D effort here at SLAC

  18. Non-uniform regulations of underground storage tanks in the United States

    International Nuclear Information System (INIS)

    Nadim, F.; Hoag, G.E.; Liu, S.; Carley, R.J.; Zack, P.

    2000-01-01

    Leaking underground storage tanks (USTs) are one of the major sources of ground water contamination. United States federal regulations for USTs were established in September of 1988. Since that time little or no amendments have been made to these regulations. In order to protect sensitive areas such as aquifer recharge zones for public water supply wells and wetlands, different states have been obligated to apply more stringent standards than the federal UST regulations. This practice however, has led to a non-uniform application of regulations for USTs throughout the country. In this article, United States regulations for USTs are reviewed and its deficits are highlighted. Based on these regulations and the experience of northeastern states of United States, a sequence of leak and spill preventive measures for USTs is proposed. Application of the proposed measures could substantially reduce the possibility of UST failure and would be more protective of the subsurface environment. (author)

  19. Is anyone regulating naturally occurring radioactive material? A state survey

    International Nuclear Information System (INIS)

    Gross, E.M.; Barisas, S.G.

    1993-08-01

    As far as we know, naturally occurring radioactive material (NORM) has surrounded humankind since the beginning of time. However, recent data demonstrating that certain activities concentrate NORM have increased concern regarding its proper handling and disposal and precipitated the development of new NORM-related regulations. The regulation of NORM affects the management of government facilities as well as a broad range of industrial processes. Recognizing that NORM regulation at the federal level is extremely limited, Argonne National Laboratory (ANL) conducted a 50-state survey to determine the extent to which states have assumed the responsibility for regulating NORM as well as the NORM standards that are currently being applied at the state level. Though the survey indicates that NORM regulation comprises a broad spectrum of controls from full licensing requirements to virtually no regulation at afl, a trend is emerging toward recognition of the need for increased regulation of potential NORM hazards, particularly in the absence of federal standards

  20. Using interpersonal affect regulation in simulated healthcare consultations: An experimental investigation of self-control resource depletion

    Directory of Open Access Journals (Sweden)

    David eMartínez-Iñigo

    2015-09-01

    Full Text Available Controlled Interpersonal Affect Regulation –the process of deliberately influencing the internal feeling states of others– occurs in a variety of interpersonal relationships and contexts. An incipient corpus of research shows that interpersonal affect regulation can be characterized as a goal-directed behaviour that uses self-control processes which, according to the strength model of self-regulation, consumes a limited resource that is also used by other self-control processes. Using interpersonal affect-improving and affect-worsening regulation strategies can increase agents´ resource depletion but there is reason to think that effects will partially rely on targets´ feedback in response to the regulation. Using a healthcare paradigm, an experiment was conducted to test the combined effects of interpersonal affect regulation use and patient feedback on healthcare workers’ resource depletion, measured as self-reported actual and expected emotional exhaustion, and persistence on a self-regulation task. Medical students (N = 78 were randomly assigned to a 2(interpersonal affect regulation: affect-worsening vs. affect-improving x 2(patients’ feedback: positive vs. negative factorial between-subjects design and given instructions to play the role of doctors in interactions with two professional actors trained to act as patients. Analysis of covariance showed that affect-worsening was more depleting than affect-improving for all measures, whereas the recovery effects of positive feedback varied depending on strategy type and measure. The findings confirm the characterization of interpersonal affect regulation as potentially depleting, but suggest that the correspondence between the agent´s strategy and the target´s response needs to be taken into consideration. Use of affect-improving and positive feedback showed positive effects on self-rated performance, indicating that interpersonal affect regulation is relevant for organizational as

  1. Using interpersonal affect regulation in simulated healthcare consultations: an experimental investigation of self-control resource depletion.

    Science.gov (United States)

    Martínez-Íñigo, David; Mercado, Francisco; Totterdell, Peter

    2015-01-01

    Controlled Interpersonal Affect Regulation -the process of deliberately influencing the internal feeling states of others- occurs in a variety of interpersonal relationships and contexts. An incipient corpus of research shows that interpersonal affect regulation can be characterized as a goal-directed behavior that uses self-control processes which, according to the strength model of self-regulation, consumes a limited resource that is also used by other self-control processes. Using interpersonal affect-improving and affect-worsening regulation strategies can increase agent's resource depletion but there is reason to think that effects will partially rely on target's feedback in response to the regulation. Using a healthcare paradigm, an experiment was conducted to test the combined effects of interpersonal affect regulation use and patient feedback on healthcare workers' resource depletion, measured as self-reported experienced and expected emotional exhaustion, and persistence on a self-regulation task. Medical students (N = 78) were randomly assigned to a 2(interpersonal affect regulation: affect-worsening vs. affect-improving) × 2(patients' feedback: positive vs. negative) factorial between-subjects design and given instructions to play the role of doctors in interactions with two professional actors trained to act as patients. Analysis of covariance showed that affect-worsening was more depleting than affect-improving for all measures, whereas the recovery effects of positive feedback varied depending on strategy type and measure. The findings confirm the characterization of interpersonal affect regulation as potentially depleting, but suggest that the correspondence between the agent's strategy and the target's response needs to be taken into consideration. Use of affect-improving and positive feedback showed positive effects on self-rated performance, indicating that interpersonal affect regulation is relevant for organizational as well as personal

  2. Switching neuronal state: optimal stimuli revealed using a stochastically-seeded gradient algorithm.

    Science.gov (United States)

    Chang, Joshua; Paydarfar, David

    2014-12-01

    Inducing a switch in neuronal state using energy optimal stimuli is relevant to a variety of problems in neuroscience. Analytical techniques from optimal control theory can identify such stimuli; however, solutions to the optimization problem using indirect variational approaches can be elusive in models that describe neuronal behavior. Here we develop and apply a direct gradient-based optimization algorithm to find stimulus waveforms that elicit a change in neuronal state while minimizing energy usage. We analyze standard models of neuronal behavior, the Hodgkin-Huxley and FitzHugh-Nagumo models, to show that the gradient-based algorithm: (1) enables automated exploration of a wide solution space, using stochastically generated initial waveforms that converge to multiple locally optimal solutions; and (2) finds optimal stimulus waveforms that achieve a physiological outcome condition, without a priori knowledge of the optimal terminal condition of all state variables. Analysis of biological systems using stochastically-seeded gradient methods can reveal salient dynamical mechanisms underlying the optimal control of system behavior. The gradient algorithm may also have practical applications in future work, for example, finding energy optimal waveforms for therapeutic neural stimulation that minimizes power usage and diminishes off-target effects and damage to neighboring tissue.

  3. Peer feedback on college students’ writing : exploring the relation between students’ ability match, feedback quality and essay performance

    NARCIS (Netherlands)

    Huisman, B.A.; Saab, N.; Van, Driel J.H.; Van, den Broek P.W.

    2017-01-01

    There does not appear to be consensus on how to optimally match students during the peer feedback process: with same-ability peers (homogeneously) or different-ability peers (heterogeneously). In fact, there appears to be no empirical evidence that either homogeneous or heterogeneous student

  4. The combination of positive and negative feedback loops confers exquisite flexibility to biochemical switches

    International Nuclear Information System (INIS)

    Pfeuty, Benjamin; Kaneko, Kunihiko

    2009-01-01

    A wide range of cellular processes require molecular regulatory pathways to convert a graded signal into a discrete response. One prevalent switching mechanism relies on the coexistence of two stable states (bistability) caused by positive feedback regulations. Intriguingly, positive feedback is often supplemented with negative feedback, raising the question of whether and how these two types of feedback can cooperate to control discrete cellular responses. To address this issue, we formulate a canonical model of a protein–protein interaction network and analyze the dynamics of a prototypical two-component circuit. The appropriate combination of negative and positive feedback loops can bring a bistable circuit close to the oscillatory regime. Notably, sharply activated negative feedback can give rise to a bistable regime wherein two stable fixed points coexist and may collide pairwise with two saddle points. This specific type of bistability is found to allow for separate and flexible control of switch-on and switch-off events, for example (i) to combine fast and reversible transitions, (ii) to enable transient switching responses and (iii) to display tunable noise-induced transition rates. Finally, we discuss the relevance of such bistable switching behavior, and the circuit topologies considered, to specific biological processes such as adaptive metabolic responses, stochastic fate decisions and cell-cycle transitions. Taken together, our results suggest an efficient mechanism by which positive and negative feedback loops cooperate to drive the flexible and multifaceted switching behaviors arising in biological systems

  5. MASS TRANSPORT AND TURBULENCE IN GRAVITATIONALLY UNSTABLE DISK GALAXIES. II. THE EFFECTS OF STAR FORMATION FEEDBACK

    Energy Technology Data Exchange (ETDEWEB)

    Goldbaum, Nathan J. [National Center for Supercomputing Applications, University of Illinois at Urbana-Champaign, 1205 W. Clark St., Urbana, IL 61801 (United States); Krumholz, Mark R. [Research School of Astronomy and Astrophysics, Australian National University, Canberra, ACT 2601 (Australia); Forbes, John C., E-mail: ngoldbau@illinois.edu [Department of Astronomy and Astrophysics, University of California, Santa Cruz, CA 95064 (United States)

    2016-08-10

    Self-gravity and stellar feedback are capable of driving turbulence and transporting mass and angular momentum in disk galaxies, but the balance between them is not well understood. In the previous paper in this series, we showed that gravity alone can drive turbulence in galactic disks, regulate their Toomre Q parameters to ∼1, and transport mass inwards at a rate sufficient to fuel star formation in the centers of present-day galaxies. In this paper we extend our models to include the effects of star formation feedback. We show that feedback suppresses galaxies’ star formation rates by a factor of ∼5 and leads to the formation of a multi-phase atomic and molecular interstellar medium. Both the star formation rate and the phase balance produced in our simulations agree well with observations of nearby spirals. After our galaxies reach steady state, we find that the inclusion of feedback actually lowers the gas velocity dispersion slightly compared to the case of pure self-gravity, and also slightly reduces the rate of inward mass transport. Nevertheless, we find that, even with feedback included, our galactic disks self-regulate to Q ∼ 1, and transport mass inwards at a rate sufficient to supply a substantial fraction of the inner disk star formation. We argue that gravitational instability is therefore likely to be the dominant source of turbulence and transport in galactic disks, and that it is responsible for fueling star formation in the inner parts of galactic disks over cosmological times.

  6. Optimal sensorimotor control in eye movement sequences.

    Science.gov (United States)

    Munuera, Jérôme; Morel, Pierre; Duhamel, Jean-René; Deneve, Sophie

    2009-03-11

    Fast and accurate motor behavior requires combining noisy and delayed sensory information with knowledge of self-generated body motion; much evidence indicates that humans do this in a near-optimal manner during arm movements. However, it is unclear whether this principle applies to eye movements. We measured the relative contributions of visual sensory feedback and the motor efference copy (and/or proprioceptive feedback) when humans perform two saccades in rapid succession, the first saccade to a visual target and the second to a memorized target. Unbeknownst to the subject, we introduced an artificial motor error by randomly "jumping" the visual target during the first saccade. The correction of the memory-guided saccade allowed us to measure the relative contributions of visual feedback and efferent copy (and/or proprioceptive feedback) to motor-plan updating. In a control experiment, we extinguished the target during the saccade rather than changing its location to measure the relative contribution of motor noise and target localization error to saccade variability without any visual feedback. The motor noise contribution increased with saccade amplitude, but remained <30% of the total variability. Subjects adjusted the gain of their visual feedback for different saccade amplitudes as a function of its reliability. Even during trials where subjects performed a corrective saccade to compensate for the target-jump, the correction by the visual feedback, while stronger, remained far below 100%. In all conditions, an optimal controller predicted the visual feedback gain well, suggesting that humans combine optimally their efferent copy and sensory feedback when performing eye movements.

  7. Negative and Positive Outflow-Feedback in Nearby (U)LIRGs

    Energy Technology Data Exchange (ETDEWEB)

    Cazzoli, Sara, E-mail: sara@iaa.es [Instituto de Astrofisica de Andalucia (CSIC), Granada (Spain)

    2017-12-15

    The starburst-AGN coexistence in local (U)LIRGs makes these galaxies excellent laboratories for the study of stellar and AGN outflows and feedback. Outflows regulate star formation and AGN activity, redistributing gas, dust and metals over large scales in the interstellar and intergalactic media (negative feedback) being also considered to be able to undergo vigorous star formation (positive feedback). In this contribution, I will summarize the results from a search for outflows in a sample of nearby 38 local (U)LIRG systems observed with VIMOS/VLT integral field unit. For two galaxies of the sample I will detail the outflow properties and discuss the observational evidence for negative and positive outflow-feedback. The assessment of both negative and positive feedback effects represent a novel approach toward a comprehensive understanding of the impact of outflow feedback in the galaxy evolution.

  8. A Port-Hamiltonian Approach to Optimal Frequency Regulation in Power Grids

    NARCIS (Netherlands)

    Stegink, Tjerk; Persis, Claudio De; Schaft, Arjan van der

    2015-01-01

    This paper studies the problem of frequency regulation in power grids, while maximizing the social welfare. Two price-based controllers are proposed; the first one an internal-model-based controller and the second one based on a continuous gradient method for optimization. Both controllers can be

  9. An Optimal Control Strategy for DC Bus Voltage Regulation in Photovoltaic System with Battery Energy Storage

    Directory of Open Access Journals (Sweden)

    Muhamad Zalani Daud

    2014-01-01

    Full Text Available This paper presents an evaluation of an optimal DC bus voltage regulation strategy for grid-connected photovoltaic (PV system with battery energy storage (BES. The BES is connected to the PV system DC bus using a DC/DC buck-boost converter. The converter facilitates the BES power charge/discharge to compensate for the DC bus voltage deviation during severe disturbance conditions. In this way, the regulation of DC bus voltage of the PV/BES system can be enhanced as compared to the conventional regulation that is solely based on the voltage-sourced converter (VSC. For the grid side VSC (G-VSC, two control methods, namely, the voltage-mode and current-mode controls, are applied. For control parameter optimization, the simplex optimization technique is applied for the G-VSC voltage- and current-mode controls, including the BES DC/DC buck-boost converter controllers. A new set of optimized parameters are obtained for each of the power converters for comparison purposes. The PSCAD/EMTDC-based simulation case studies are presented to evaluate the performance of the proposed optimized control scheme in comparison to the conventional methods.

  10. An optimal control strategy for DC bus voltage regulation in photovoltaic system with battery energy storage.

    Science.gov (United States)

    Daud, Muhamad Zalani; Mohamed, Azah; Hannan, M A

    2014-01-01

    This paper presents an evaluation of an optimal DC bus voltage regulation strategy for grid-connected photovoltaic (PV) system with battery energy storage (BES). The BES is connected to the PV system DC bus using a DC/DC buck-boost converter. The converter facilitates the BES power charge/discharge to compensate for the DC bus voltage deviation during severe disturbance conditions. In this way, the regulation of DC bus voltage of the PV/BES system can be enhanced as compared to the conventional regulation that is solely based on the voltage-sourced converter (VSC). For the grid side VSC (G-VSC), two control methods, namely, the voltage-mode and current-mode controls, are applied. For control parameter optimization, the simplex optimization technique is applied for the G-VSC voltage- and current-mode controls, including the BES DC/DC buck-boost converter controllers. A new set of optimized parameters are obtained for each of the power converters for comparison purposes. The PSCAD/EMTDC-based simulation case studies are presented to evaluate the performance of the proposed optimized control scheme in comparison to the conventional methods.

  11. Interaction in Spoken Word Recognition Models: Feedback Helps

    Science.gov (United States)

    Magnuson, James S.; Mirman, Daniel; Luthra, Sahil; Strauss, Ted; Harris, Harlan D.

    2018-01-01

    Human perception, cognition, and action requires fast integration of bottom-up signals with top-down knowledge and context. A key theoretical perspective in cognitive science is the interactive activation hypothesis: forward and backward flow in bidirectionally connected neural networks allows humans and other biological systems to approximate optimal integration of bottom-up and top-down information under real-world constraints. An alternative view is that online feedback is neither necessary nor helpful; purely feed forward alternatives can be constructed for any feedback system, and online feedback could not improve processing and would preclude veridical perception. In the domain of spoken word recognition, the latter view was apparently supported by simulations using the interactive activation model, TRACE, with and without feedback: as many words were recognized more quickly without feedback as were recognized faster with feedback, However, these simulations used only a small set of words and did not address a primary motivation for interaction: making a model robust in noise. We conducted simulations using hundreds of words, and found that the majority were recognized more quickly with feedback than without. More importantly, as we added noise to inputs, accuracy and recognition times were better with feedback than without. We follow these simulations with a critical review of recent arguments that online feedback in interactive activation models like TRACE is distinct from other potentially helpful forms of feedback. We conclude that in addition to providing the benefits demonstrated in our simulations, online feedback provides a plausible means of implementing putatively distinct forms of feedback, supporting the interactive activation hypothesis. PMID:29666593

  12. Interaction in Spoken Word Recognition Models: Feedback Helps.

    Science.gov (United States)

    Magnuson, James S; Mirman, Daniel; Luthra, Sahil; Strauss, Ted; Harris, Harlan D

    2018-01-01

    Human perception, cognition, and action requires fast integration of bottom-up signals with top-down knowledge and context. A key theoretical perspective in cognitive science is the interactive activation hypothesis: forward and backward flow in bidirectionally connected neural networks allows humans and other biological systems to approximate optimal integration of bottom-up and top-down information under real-world constraints. An alternative view is that online feedback is neither necessary nor helpful; purely feed forward alternatives can be constructed for any feedback system, and online feedback could not improve processing and would preclude veridical perception. In the domain of spoken word recognition, the latter view was apparently supported by simulations using the interactive activation model, TRACE, with and without feedback: as many words were recognized more quickly without feedback as were recognized faster with feedback, However, these simulations used only a small set of words and did not address a primary motivation for interaction: making a model robust in noise. We conducted simulations using hundreds of words, and found that the majority were recognized more quickly with feedback than without. More importantly, as we added noise to inputs, accuracy and recognition times were better with feedback than without. We follow these simulations with a critical review of recent arguments that online feedback in interactive activation models like TRACE is distinct from other potentially helpful forms of feedback. We conclude that in addition to providing the benefits demonstrated in our simulations, online feedback provides a plausible means of implementing putatively distinct forms of feedback, supporting the interactive activation hypothesis.

  13. Interaction in Spoken Word Recognition Models: Feedback Helps

    Directory of Open Access Journals (Sweden)

    James S. Magnuson

    2018-04-01

    Full Text Available Human perception, cognition, and action requires fast integration of bottom-up signals with top-down knowledge and context. A key theoretical perspective in cognitive science is the interactive activation hypothesis: forward and backward flow in bidirectionally connected neural networks allows humans and other biological systems to approximate optimal integration of bottom-up and top-down information under real-world constraints. An alternative view is that online feedback is neither necessary nor helpful; purely feed forward alternatives can be constructed for any feedback system, and online feedback could not improve processing and would preclude veridical perception. In the domain of spoken word recognition, the latter view was apparently supported by simulations using the interactive activation model, TRACE, with and without feedback: as many words were recognized more quickly without feedback as were recognized faster with feedback, However, these simulations used only a small set of words and did not address a primary motivation for interaction: making a model robust in noise. We conducted simulations using hundreds of words, and found that the majority were recognized more quickly with feedback than without. More importantly, as we added noise to inputs, accuracy and recognition times were better with feedback than without. We follow these simulations with a critical review of recent arguments that online feedback in interactive activation models like TRACE is distinct from other potentially helpful forms of feedback. We conclude that in addition to providing the benefits demonstrated in our simulations, online feedback provides a plausible means of implementing putatively distinct forms of feedback, supporting the interactive activation hypothesis.

  14. Obesity prevention in child care: A review of U.S. state regulations

    Directory of Open Access Journals (Sweden)

    Slining Meghan

    2008-05-01

    Full Text Available ABSTRACT Objective To describe and contrast individual state nutrition and physical activity regulations related to childhood obesity for child care centers and family child care homes in the United States. Methods We conducted a review of regulations for child care facilities for all 50 states and the District of Columbia. We examined state regulations and recorded key nutrition and physical activity items that may contribute to childhood obesity. Items included in this review were: 1 Water is freely available; 2 Sugar-sweetened beverages are limited; 3 Foods of low nutritional value are limited; 4 Children are not forced to eat; 5 Food is not used as a reward; 6 Support is provided for breastfeeding and provision of breast milk; 7 Screen time is limited; and 8 Physical activity is required daily. Results Considerable variation exists among state nutrition and physical activity regulations related to obesity. Tennessee had six of the eight regulations for child care centers, and Delaware, Georgia, Indiana, and Nevada had five of the eight regulations. Conversely, the District of Columbia, Idaho, Nebraska and Washington had none of the eight regulations. For family child care homes, Georgia and Nevada had five of the eight regulations; Arizona, Mississippi, North Carolina, Oregon, Tennessee, Texas, Vermont, and West Virginia had four of the eight regulations. California, the District of Columbia, Idaho, Iowa, Kansas, and Nebraska did not have any of the regulations related to obesity for family child care homes. Conclusion Many states lack specific nutrition and physical activity regulations related to childhood obesity for child care facilities. If widely implemented, enhancing state regulations could help address the obesity epidemic in young children in the United States.

  15. Output feedback dissipation control for the power-level of modular high-temperature gas-cooled reactors

    International Nuclear Information System (INIS)

    Dong, Z.

    2011-01-01

    Because of its strong inherent safety features and the high outlet temperature, the modular high temperature gas-cooled nuclear reactor (MHTGR) is the chosen technology for a new generation of nuclear power plants. Such power plants are being considered for industrial applications with a wide range of power levels, thus power-level regulation is very important for their efficient and stable operation. Exploiting the large scale asymptotic closed-loop stability provided by nonlinear controllers, a nonlinear power-level regulator is presented in this paper that is based upon both the techniques of feedback dissipation and well-established backstepping. The virtue of this control strategy, i.e., the ability of globally asymptotic stabilization, is that it takes advantage of the inherent zero-state detectability property of the MHTGR dynamics. Moreover, this newly built power-level regulator is also robust towards modeling uncertainty in the control rod dynamics. If modeling uncertainty of the control rod dynamics is small enough to be omitted, then this control law can be simplified to a classical proportional feedback controller. The comparison of the control performance between the newly-built power controller and the simplified controller is also given through numerical study and theoretical analysis. (author)

  16. Truncated predictor feedback for time-delay systems

    CERN Document Server

    Zhou, Bin

    2014-01-01

    This book provides a systematic approach to the design of predictor based controllers for (time-varying) linear systems with either (time-varying) input or state delays. Differently from those traditional predictor based controllers, which are infinite-dimensional static feedback laws and may cause difficulties in their practical implementation, this book develops a truncated predictor feedback (TPF) which involves only finite dimensional static state feedback. Features and topics: A novel approach referred to as truncated predictor feedback for the stabilization of (time-varying) time-delay systems in both the continuous-time setting and the discrete-time setting is built systematically Semi-global and global stabilization problems of linear time-delay systems subject to either magnitude saturation or energy constraints are solved in a systematic manner Both stabilization of a single system and consensus of a group of systems (multi-agent systems) are treated in a unified manner by applying the truncated pre...

  17. Nonlinear Output Feedback Control of Underwater Vehicle Propellers using Advance Speed Feedback

    DEFF Research Database (Denmark)

    Fossen, T.I.; Blanke, M.

    1999-01-01

    More accurate propeller shaft speed controllers can be designed by using nonlinear control theory. In this paper, an output feedback controller reconstructing the advance speed (speed of water going into the propeller) from vehicle speed measurements is derived. For this purpose a three-state model...... minimizes thruster losses due to variations in propeller axial inlet flow which is a major problem when applying conventional vehicle-propeller control systems. The proposed controller is simulated for an underwater vehicle equipped with a single propeller. From the simulations it can be concluded...... of propeller shaft speed, forward (surge) speed of the vehicle and axial inlet flow of the propeller is applied. A nonlinear observer in combination with an output feedback integral controller are derived by applying Lyapunov stability theory and exponential stability is proven. The output feedback controller...

  18. Generalized fast feedback system in the SLC

    International Nuclear Information System (INIS)

    Hendrickson, L.; Allison, S.; Gromme, T.; Himel, T.; Krauter, K.; Rouse, F.; Sass, R.; Shoaee, H.

    1992-01-01

    A generalized fast feedback system has been developed to stabilize beams at various locations in the SLC. The system is designed to perform measurements and change actuator settings to control beam states such as position, angle and energy on a pulse to pulse basis. The software design is based on the state space formalism of digital control theory. The system is database-driven, facilitating the addition of new loops without requiring additional software. A communications system, KISNet, provides fast communications links between microprocessors for feedback loops which involve multiple micros. Feedback loops have been installed in seventeen locations throughout the SLC and have proven to be invaluable in stabilizing the machine. (author)

  19. Bifurcation analysis of a delay reaction-diffusion malware propagation model with feedback control

    Science.gov (United States)

    Zhu, Linhe; Zhao, Hongyong; Wang, Xiaoming

    2015-05-01

    With the rapid development of network information technology, information networks security has become a very critical issue in our work and daily life. This paper attempts to develop a delay reaction-diffusion model with a state feedback controller to describe the process of malware propagation in mobile wireless sensor networks (MWSNs). By analyzing the stability and Hopf bifurcation, we show that the state feedback method can successfully be used to control unstable steady states or periodic oscillations. Moreover, formulas for determining the properties of the bifurcating periodic oscillations are derived by applying the normal form method and center manifold theorem. Finally, we conduct extensive simulations on large-scale MWSNs to evaluate the proposed model. Numerical evidences show that the linear term of the controller is enough to delay the onset of the Hopf bifurcation and the properties of the bifurcation can be regulated to achieve some desirable behaviors by choosing the appropriate higher terms of the controller. Furthermore, we obtain that the spatial-temporal dynamic characteristics of malware propagation are closely related to the rate constant for nodes leaving the infective class for recovered class and the mobile behavior of nodes.

  20. THE EUROPEAN MODEL OF STATE REGULATION OF TOURISM ACTIVITIES

    Directory of Open Access Journals (Sweden)

    О. Davydova

    2013-11-01

    Full Text Available In the article the existing model of state regulation of the development of tourism. Expediency of the European model of state regulation of tourism development in Ukraine. It is noted that the European model of state regulation of tourism activities based on the coordination of marketing activities and the development of cooperation between the public and private sectors. The basic forms of public-private partnerships and the advantages of using cluster model of development of tourism, namely, contracts, production sharing agreement, lease, joint venture. Promising areas of application of the PPP identified the transport sector, housing and utilities, energy and tourism sector. The features of cluster formations in the country and the prospects for tourism clusters.

  1. Global desertification: Drivers and feedbacks

    Science.gov (United States)

    D'Odorico, Paolo; Bhattachan, Abinash; Davis, Kyle F.; Ravi, Sujith; Runyan, Christiane W.

    2013-01-01

    Desertification is a change in soil properties, vegetation or climate, which results in a persistent loss of ecosystem services that are fundamental to sustaining life. Desertification affects large dryland areas around the world and is a major cause of stress in human societies. Here we review recent research on the drivers, feedbacks, and impacts of desertification. A multidisciplinary approach to understanding the drivers and feedbacks of global desertification is motivated by our increasing need to improve global food production and to sustainably manage ecosystems in the context of climate change. Classic desertification theories look at this process as a transition between stable states in bistable ecosystem dynamics. Climate change (i.e., aridification) and land use dynamics are the major drivers of an ecosystem shift to a “desertified” (or “degraded”) state. This shift is typically sustained by positive feedbacks, which stabilize the system in the new state. Desertification feedbacks may involve land degradation processes (e.g., nutrient loss or salinization), changes in rainfall regime resulting from land-atmosphere interactions (e.g., precipitation recycling, dust emissions), or changes in plant community composition (e.g., shrub encroachment, decrease in vegetation cover). We analyze each of these feedback mechanisms and discuss their possible enhancement by interactions with socio-economic drivers. Large scale effects of desertification include the emigration of “environmental refugees” displaced from degraded areas, climatic changes, and the alteration of global biogeochemical cycles resulting from the emission and long-range transport of fine mineral dust. Recent research has identified some possible early warning signs of desertification, which can be used as indicators of resilience loss and imminent shift to desert-like conditions. We conclude with a brief discussion on some desertification control strategies implemented in different

  2. Delayed feedback control of fractional-order chaotic systems

    International Nuclear Information System (INIS)

    Gjurchinovski, A; Urumov, V; Sandev, T

    2010-01-01

    We study the possibility to stabilize unstable steady states and unstable periodic orbits in chaotic fractional-order dynamical systems by the time-delayed feedback method. By performing a linear stability analysis, we establish the parameter ranges for successful stabilization of unstable equilibria in the plane parameterized by the feedback gain and the time delay. An insight into the control mechanism is gained by analyzing the characteristic equation of the controlled system, showing that the control scheme fails to control unstable equilibria having an odd number of positive real eigenvalues. We demonstrate that the method can also stabilize unstable periodic orbits for a suitable choice of the feedback gain, providing that the time delay is chosen to coincide with the period of the target orbit. In addition, it is shown numerically that delayed feedback control with a sinusoidally modulated time delay significantly enlarges the stability region of steady states in comparison to the classical time-delayed feedback scheme with a constant delay.

  3. Optimal Scheduling of an Regional Integrated Energy System with Energy Storage Systems for Service Regulation

    Directory of Open Access Journals (Sweden)

    Hengrui Ma

    2018-01-01

    Full Text Available Ancillary services are critical to maintaining the safe and stable operation of power systems that contain a high penetration level of renewable energy resources. As a high-quality regulation resource, the regional integrated energy system (RIES with energy storage system (ESS can effectively adjust the non-negligible frequency offset caused by the renewable energy integration into the power system, and help solve the problem of power system frequency stability. In this paper, the optimization model aiming at regional integrated energy system as a participant in the regulation market based on pay-for-performance is established. Meanwhile YALMIP + CPLEX is used to simulate and analyze the total operating cost under different dispatch modes. This paper uses the actual operation model of the PJM regulation market to guide the optimal allocation of regulation resource in the regional integrated energy system, and provides a balance between the power trading revenue and regulation market revenue in order to achieve the maximum profit.

  4. Nonlinear output feedback control of underwater vehicle propellers using feedback form estimated axial flow velocity

    DEFF Research Database (Denmark)

    Fossen, T. I.; Blanke, Mogens

    2000-01-01

    Accurate propeller shaft speed controllers can be designed by using nonlinear control theory and feedback from the axial water velocity in the propeller disc. In this paper, an output feedback controller is derived, reconstructing the axial flow velocity from vehicle speed measurements, using...... a three-state model of propeller shaft speed, forward (surge) speed of the vehicle, and the axial flow velocity. Lyapunov stability theory is used to prove that a nonlinear observer combined with an output feedback integral controller provide exponential stability. The output feedback controller...... compensates for variations in thrust due to time variations in advance speed. This is a major problem when applying conventional vehicle-propeller control systems, The proposed controller is simulated for an underwater vehicle equipped with a single propeller. The simulations demonstrate that the axial water...

  5. Projective Synchronization of N-Dimensional Chaotic Fractional-Order Systems via Linear State Error Feedback Control

    Directory of Open Access Journals (Sweden)

    Baogui Xin

    2012-01-01

    Full Text Available Based on linear feedback control technique, a projective synchronization scheme of N-dimensional chaotic fractional-order systems is proposed, which consists of master and slave fractional-order financial systems coupled by linear state error variables. It is shown that the slave system can be projectively synchronized with the master system constructed by state transformation. Based on the stability theory of linear fractional order systems, a suitable controller for achieving synchronization is designed. The given scheme is applied to achieve projective synchronization of chaotic fractional-order financial systems. Numerical simulations are given to verify the effectiveness of the proposed projective synchronization scheme.

  6. Self-controlled feedback is effective if it is based on the learner's performance: a replication and extension of Chiviacowsky and Wulf (2005).

    Science.gov (United States)

    Carter, Michael J; Carlsen, Anthony N; Ste-Marie, Diane M

    2014-01-01

    The learning advantages of self-controlled feedback schedules compared to yoked schedules have been attributed to motivational influences and/or information processing activities with many researchers adopting the motivational perspective in recent years. Chiviacowsky and Wulf (2005) found that feedback decisions made before (Self-Before) or after a trial (Self-After) resulted in similar retention performance, but superior transfer performance resulted when the decision to receive feedback occurred after a trial. They suggested that the superior skill transfer of the Self-After group likely emerged from information processing activities such as error estimation. However, the lack of yoked groups and a measure of error estimation in their experimental design prevents conclusions being made regarding the underlying mechanisms of why self-controlled feedback schedules optimize learning. Here, we revisited Chiviacowsky and Wulf's (2005) design to investigate the learning benefits of self-controlled feedback schedules. We replicated their Self-Before and Self-After groups, but added a Self-Both group that was able to request feedback before a trial, but could then change or stay with their original choice after the trial. Importantly, yoked groups were included for the three self-controlled groups to address the previously stated methodological limitation and error estimations were included to examine whether self-controlling feedback facilitates a more accurate error detection and correction mechanism. The Self-After and Self-Before groups demonstrated similar accuracy in physical performance and error estimation scores in retention and transfer, and both groups were significantly more accurate than the Self-Before group and their respective Yoked groups (p's 0.05). We suggest these findings further indicate that informational factors associated with the processing of feedback for the development of one's error detection and correction mechanism, rather than

  7. Feedback attitude sliding mode regulation control of spacecraft using arm motion

    Science.gov (United States)

    Shi, Ye; Liang, Bin; Xu, Dong; Wang, Xueqian; Xu, Wenfu

    2013-09-01

    The problem of spacecraft attitude regulation based on the reaction of arm motion has attracted extensive attentions from both engineering and academic fields. Most of the solutions of the manipulator’s motion tracking problem just achieve asymptotical stabilization performance, so that these controllers cannot realize precise attitude regulation because of the existence of non-holonomic constraints. Thus, sliding mode control algorithms are adopted to stabilize the tracking error with zero transient process. Due to the switching effects of the variable structure controller, once the tracking error reaches the designed hyper-plane, it will be restricted to this plane permanently even with the existence of external disturbances. Thus, precise attitude regulation can be achieved. Furthermore, taking the non-zero initial tracking errors and chattering phenomenon into consideration, saturation functions are used to replace sign functions to smooth the control torques. The relations between the upper bounds of tracking errors and the controller parameters are derived to reveal physical characteristic of the controller. Mathematical models of free-floating space manipulator are established and simulations are conducted in the end. The results show that the spacecraft’s attitude can be regulated to the position as desired by using the proposed algorithm, the steady state error is 0.000 2 rad. In addition, the joint tracking trajectory is smooth, the joint tracking errors converges to zero quickly with a satisfactory continuous joint control input. The proposed research provides a feasible solution for spacecraft attitude regulation by using arm motion, and improves the precision of the spacecraft attitude regulation.

  8. Smart conjugated polymer nanocarrier for healthy weight loss by negative feedback regulation of lipase activity

    Science.gov (United States)

    Chen, Yu-Lei; Zhu, Sha; Zhang, Lei; Feng, Pei-Jian; Yao, Xi-Kuang; Qian, Cheng-Gen; Zhang, Can; Jiang, Xi-Qun; Shen, Qun-Dong

    2016-02-01

    Healthy weight loss represents a real challenge when obesity is increasing in prevalence. Herein, we report a conjugated polymer nanocarrier for smart deactivation of lipase and thus balancing calorie intake. After oral administration, the nanocarrier is sensitive to lipase in the digestive tract and releases orlistat, which deactivates the enzyme and inhibits fat digestion. It also creates negative feedback to control the release of itself. The nanocarrier smartly regulates activity of the lipase cyclically varied between high and low levels. In spite of high fat diet intervention, obese mice receiving a single dose of the nanocarrier lose weight over eight days, whereas a control group continues the tendency to gain weight. Daily intragastric administration of the nanocarrier leads to lower weight of livers or fat pads, smaller adipocyte size, and lower total cholesterol level than that of the control group. Near-infrared fluorescence of the nanocarrier reveals its biodistribution.Healthy weight loss represents a real challenge when obesity is increasing in prevalence. Herein, we report a conjugated polymer nanocarrier for smart deactivation of lipase and thus balancing calorie intake. After oral administration, the nanocarrier is sensitive to lipase in the digestive tract and releases orlistat, which deactivates the enzyme and inhibits fat digestion. It also creates negative feedback to control the release of itself. The nanocarrier smartly regulates activity of the lipase cyclically varied between high and low levels. In spite of high fat diet intervention, obese mice receiving a single dose of the nanocarrier lose weight over eight days, whereas a control group continues the tendency to gain weight. Daily intragastric administration of the nanocarrier leads to lower weight of livers or fat pads, smaller adipocyte size, and lower total cholesterol level than that of the control group. Near-infrared fluorescence of the nanocarrier reveals its biodistribution

  9. Optimal control approaches for aircraft conflict avoidance using speed regulation : a numerical study

    OpenAIRE

    Cellier , Loïc; Cafieri , Sonia; Messine , Frederic

    2013-01-01

    International audience; In this paper a numerical study is provided to solve the aircraft conflict avoidance problem through velocity regulation maneuvers. Starting from optimal controlbased model and approaches in which aircraft accelerations are the controls, and by applying the direct shooting technique, we propose to study two different largescale nonlinear optimization problems. In order to compare different possibilities of implementation, two environments (AMPL and MATLAB) and determin...

  10. Robust wide-range control of nuclear reactors by using the feedforward-feedback concept

    International Nuclear Information System (INIS)

    Weng, C.K.; Edwards, R.M.; Ray, A.

    1994-01-01

    A robust feedforward-feedback controller is proposed for wide-range operations of nuclear reactors. This control structure provides (a) optimized performance over a wide operating range resulting form the feedforward element and (b) guaranteed robust stability and performance resulting from the feedback element. The feedforward control law is synthesized via nonlinear programming, which generates an optimal control sequence over a finite-time horizon under specified constraints. The feedback control is synthesized via the structured singular value μ approach to guarantee robustness in the presence of disturbances and modeling uncertainties. The results of simulation experiments are presented to demonstrate efficacy of the proposed control structure for a large rapid power reduction to avoid unnecessary plant trips

  11. Feedforward/feedback control synthesis for performance and robustness

    Science.gov (United States)

    Wie, Bong; Liu, Qiang

    1990-01-01

    Both feedforward and feedback control approaches for uncertain dynamical systems are investigated. The control design objective is to achieve a fast settling time (high performance) and robustness (insensitivity) to plant modeling uncertainty. Preshapong of an ideal, time-optimal control input using a 'tapped-delay' filter is shown to provide a rapid maneuver with robust performance. A robust, non-minimum-phase feedback controller is synthesized with particular emphasis on its proper implementation for a non-zero set-point control problem. The proposed feedforward/feedback control approach is robust for a certain class of uncertain dynamical systems, since the control input command computed for a given desired output does not depend on the plant parameters.

  12. Projective Synchronization of Chaotic Discrete Dynamical Systems via Linear State Error Feedback Control

    Directory of Open Access Journals (Sweden)

    Baogui Xin

    2015-04-01

    Full Text Available A projective synchronization scheme for a kind of n-dimensional discrete dynamical system is proposed by means of a linear feedback control technique. The scheme consists of master and slave discrete dynamical systems coupled by linear state error variables. A kind of novel 3-D chaotic discrete system is constructed, to which the test for chaos is applied. By using the stability principles of an upper or lower triangular matrix, two controllers for achieving projective synchronization are designed and illustrated with the novel systems. Lastly some numerical simulations are employed to validate the effectiveness of the proposed projective synchronization scheme.

  13. Generating optimal states for a homodyne Bell test

    International Nuclear Information System (INIS)

    Daffer, S.; Knight, P.L.

    2005-01-01

    Full text: We present a protocol that produces a conditionally prepared state that can be used for a Bell test based on homodyne detection. Based on the results of Munro, the state is near-optimal for Bell inequality violations based on quadrature-phase homodyne measurements that use correlated photon-number states. The scheme utilizes the Gaussian entanglement distillation protocol of Eisert et. al. and uses only beam splitters and photodetection to conditionally prepare a non-Gaussian state from a source of two-mode squeezed states with low squeezing parameter, permitting a loophole-free test of Bell inequalities. (author)

  14. Beam-based Feedback Simulations for the NLC Linac

    International Nuclear Information System (INIS)

    Hendrickson, Linda

    2000-01-01

    Extensive beam-based feedback systems are planned as an integral part of the Next Linear Collider (NLC) control system. Wakefield effects are a significant influence on the feedback design, imposing both architectural and algorithmic constraints. Studies are in progress to assure the optimal selection of devices and to refine and confirm the algorithms for the system design. The authors show the results of initial simulations, along with evaluations of system response for various conditions of ground motion and other operational disturbances

  15. Using sampled-data feedback control and linear feedback synchronization in a new hyperchaotic system

    International Nuclear Information System (INIS)

    Zhao Junchan; Lu Junan

    2008-01-01

    This paper investigates control and synchronization of a new hyperchaotic system which was proposed by [Chen A, Lu J-A, Lue J, Yu S. Generating hyperchaotic Lue attractor via state feedback control. Physica A 2006;364:103-10]. Firstly, we give different sampled-data feedback control schemes with the variation of system parameter d. Specifically, we only use one controller to drive the system to the origin when d element of (-0.35, 0), and use two controllers if d element of [0, 1.3]. Next, we combine PC method with linear feedback approach to realize synchronization, and derive similar conclusions with varying d. Numerical simulations are also given to validate the proposed approaches

  16. Robust back-stepping output feedback trajectory tracking for quadrotors via extended state observer and sigmoid tracking differentiator

    Science.gov (United States)

    Shao, Xingling; Liu, Jun; Wang, Honglun

    2018-05-01

    In this paper, a robust back-stepping output feedback trajectory tracking controller is proposed for quadrotors subject to parametric uncertainties and external disturbances. Based on the hierarchical control principle, the quadrotor dynamics is decomposed into translational and rotational subsystems to facilitate the back-stepping control design. With given model information incorporated into observer design, a high-order extended state observer (ESO) that relies only on position measurements is developed to estimate the remaining unmeasurable states and the lumped disturbances in rotational subsystem simultaneously. To overcome the problem of "explosion of complexity" in the back-stepping design, the sigmoid tracking differentiator (STD) is introduced to compute the derivative of virtual control laws. The advantage is that the proposed controller via output-feedback scheme not only can ensure good tracking performance using very limited information of quadrotors, but also has the ability of handling the undesired uncertainties. The stability analysis is established using the Lyapunov theory. Simulation results demonstrate the effectiveness of the proposed control scheme in achieving a guaranteed tracking performance with respect to an 8-shaped reference trajectory.

  17. Opportunistic Relay Selection With Limited Feedback

    KAUST Repository

    Eltayeb, Mohammed E.

    2015-08-01

    Relay selection is a simple technique that achieves spatial diversity in cooperative relay networks. Generally, relay selection algorithms require channel state information (CSI) feedback from all cooperating relays to make a selection decision. This requirement poses two important challenges, which are often neglected in the literature. Firstly, the fed back channel information is usually corrupted by additive noise. Secondly, CSI feedback generates a great deal of feedback overhead (air-time) that could result in significant performance hits. In this paper, we propose a compressive sensing (CS) based relay selection algorithm that reduces the feedback overhead of relay networks under the assumption of noisy feedback channels. The proposed algorithm exploits CS to first obtain the identity of a set of relays with favorable channel conditions. Following that, the CSI of the identified relays is estimated using least squares estimation without any additional feedback. Both single and multiple relay selection cases are considered. After deriving closed-form expressions for the asymptotic end-to-end SNR at the destination and the feedback load for different relaying protocols, we show that CS-based selection drastically reduces the feedback load and achieves a rate close to that obtained by selection algorithms with dedicated error-free feedback. © 1972-2012 IEEE.

  18. Linear feedback control, adaptive feedback control and their combination for chaos (lag) synchronization of LC chaotic systems

    International Nuclear Information System (INIS)

    Yan Zhenya; Yu Pei

    2007-01-01

    In this paper, we study chaos (lag) synchronization of a new LC chaotic system, which can exhibit not only a two-scroll attractor but also two double-scroll attractors for different parameter values, via three types of state feedback controls: (i) linear feedback control; (ii) adaptive feedback control; and (iii) a combination of linear feedback and adaptive feedback controls. As a consequence, ten families of new feedback control laws are designed to obtain global chaos lag synchronization for τ < 0 and global chaos synchronization for τ = 0 of the LC system. Numerical simulations are used to illustrate these theoretical results. Each family of these obtained feedback control laws, including two linear (adaptive) functions or one linear function and one adaptive function, is added to two equations of the LC system. This is simpler than the known synchronization controllers, which apply controllers to all equations of the LC system. Moreover, based on the obtained results of the LC system, we also derive the control laws for chaos (lag) synchronization of another new type of chaotic system

  19. Beam closed orbit feedback based on PID control

    International Nuclear Information System (INIS)

    Xuan Ke; Wang Lin; Liu Gongfa; Li Weimin; Li Chuan; Wang Jigang; Bao Xun; Xu Hongliang

    2013-01-01

    The algorithm in the feedback system has important influence on the performance of the beam orbit. Good feedback algorithm can greatly improve the beam orbit stability. In this paper, the theory of beam closed orbit correction, the principle of PID control and the beam closed orbit feedback correction using PID control were introduced. The simulation results were given. Compared with least-square method, the PID feedback algorithm makes the steady-state error smaller and more accurate, and enhances the beam orbit stability. (authors)

  20. Essays on optimal capacity and optimal regulation of interconnection infrastructures

    Science.gov (United States)

    Boffa, Federico

    The integration between geographically differentiated markets or between vertically related industries generate effects on welfare that depend on the structure of the underlying markets. My thesis investigates the impact of geographical interconnection on welfare, and illustrates welfare-enhancing modes of regulation of vertically integrated industries and of geographically integrated markets. The first chapter analyzes the effects of interconnection between two formerly fully-separated markets under the assumptions that producers in the two markets are capacity-constrained, and tacitly collude whenever it is rational for them to do so. I find that there exists a set of assumptions under which interconnection brings about greater collusion, hence it reduces overall welfare. The second chapter analyzes the optimal interconnection capacity allocation mechanism for a benevolent electricity regulator when generation is not competitive. The regulator's intervention should not only ensure that interconnection capacity is efficiently allocated to the most efficient firms, but it should also induce a higher welfare in the upstream generation market. In a two-node setting, with one firm per node, I show that the regulatory intervention becomes more effective as the cost asymmetries between the two firms become more pronounced. The third chapter illustrates a regulation mechanism for vertically related industries. Ownership shares of the upstream industry (that displays economies of scale) are allocated to the downstream (competitive) firms in proportion to their shares in the final goods market. I show that the mechanism combines the benefits of vertical integration with those of vertical separation. The advantages of vertical integration consist in avoiding double marginalization, and in internalizing the reduction in average cost resulting from the upstream increase in output; on the other hand, vertical separation allows to preserve the competitiveness of the downstream

  1. Follower-Centered Perspective on Feedback: Effects of Feedback Seeking on Identification and Feedback Environment

    OpenAIRE

    Gong, Zhenxing; Li, Miaomiao; Qi, Yaoyuan; Zhang, Na

    2017-01-01

    In the formation mechanism of the feedback environment, the existing research pays attention to external feedback sources and regards individuals as objects passively accepting feedback. Thus, the external source fails to realize the individuals’ need for feedback, and the feedback environment cannot provide them with useful information, leading to a feedback vacuum. The aim of this study is to examine the effect of feedback-seeking by different strategies on the supervisor-feedback environme...

  2. Optimized control strategy for crowbarless solid state modular power supply

    International Nuclear Information System (INIS)

    Upadhyay, R.; Badapanda, M.K.; Tripathi, A.; Hannurkar, P.R.; Pithawa, C.K.

    2009-01-01

    Solid state modular power supply with series connected IGBT based power modules have been employed as high voltage bias power supply of klystron amplifier. Auxiliary compensation of full wave inverter bridge with ZVS/ZCS operations of all IGBTs over entire operating range is incorporated. An optimized control strategy has been adopted for this power supply needing no output filter, making this scheme crowbarless and is presented in this paper. DSP based fully digital control with same duty cycle for all power modules, have been incorporated for regulating this power supply along with adequate protection features. Input to this power supply is taken directly from 11 kV line and the input system is intentionally made 24 pulsed to reduce the input harmonics, improve the input power factor significantly, there by requiring no line filters. Various steps have been taken to increase the efficiency of major subsystems, so as to improve the overall efficiency of this power supply significantly. (author)

  3. Neural networks for feedback feedforward nonlinear control systems.

    Science.gov (United States)

    Parisini, T; Zoppoli, R

    1994-01-01

    This paper deals with the problem of designing feedback feedforward control strategies to drive the state of a dynamic system (in general, nonlinear) so as to track any desired trajectory joining the points of given compact sets, while minimizing a certain cost function (in general, nonquadratic). Due to the generality of the problem, conventional methods are difficult to apply. Thus, an approximate solution is sought by constraining control strategies to take on the structure of multilayer feedforward neural networks. After discussing the approximation properties of neural control strategies, a particular neural architecture is presented, which is based on what has been called the "linear-structure preserving principle". The original functional problem is then reduced to a nonlinear programming one, and backpropagation is applied to derive the optimal values of the synaptic weights. Recursive equations to compute the gradient components are presented, which generalize the classical adjoint system equations of N-stage optimal control theory. Simulation results related to nonlinear nonquadratic problems show the effectiveness of the proposed method.

  4. Optimal experiment design for quantum state tomography: Fair, precise, and minimal tomography

    International Nuclear Information System (INIS)

    Nunn, J.; Smith, B. J.; Puentes, G.; Walmsley, I. A.; Lundeen, J. S.

    2010-01-01

    Given an experimental setup and a fixed number of measurements, how should one take data to optimally reconstruct the state of a quantum system? The problem of optimal experiment design (OED) for quantum state tomography was first broached by Kosut et al.[R. Kosut, I. Walmsley, and H. Rabitz, e-print arXiv:quant-ph/0411093 (2004)]. Here we provide efficient numerical algorithms for finding the optimal design, and analytic results for the case of 'minimal tomography'. We also introduce the average OED, which is independent of the state to be reconstructed, and the optimal design for tomography (ODT), which minimizes tomographic bias. Monte Carlo simulations confirm the utility of our results for qubits. Finally, we adapt our approach to deal with constrained techniques such as maximum-likelihood estimation. We find that these are less amenable to optimization than cruder reconstruction methods, such as linear inversion.

  5. Packetized Media Streaming with Comprehensive Exploitation of Feedback Information

    OpenAIRE

    De Vleeschouwer, C.; Frossard, P.

    2005-01-01

    This paper addresses the problem of streaming packetized media over a lossy packet network, with sender-driven (re)transmission using acknowledgement feedback. The different transmission scenarios associated to a group of interdependent media data units are abstracted in terms of a finite alphabet of policies, for each single data unit. A rate-distortion optimized markovian framework is proposed, which supports the use of comprehensive feedback information. Contrarily to previous works in rat...

  6. Optimal reducibility of all W states equivalent under stochastic local operations and classical communication

    Energy Technology Data Exchange (ETDEWEB)

    Rana, Swapan; Parashar, Preeti [Physics and Applied Mathematics Unit, Indian Statistical Institute, 203 BT Road, Kolkata (India)

    2011-11-15

    We show that all multipartite pure states that are stochastic local operation and classical communication (SLOCC) equivalent to the N-qubit W state can be uniquely determined (among arbitrary states) from their bipartite marginals. We also prove that only (N-1) of the bipartite marginals are sufficient and that this is also the optimal number. Thus, contrary to the Greenberger-Horne-Zeilinger (GHZ) class, W-type states preserve their reducibility under SLOCC. We also study the optimal reducibility of some larger classes of states. The generic Dicke states |GD{sub N}{sup l}> are shown to be optimally determined by their (l+1)-partite marginals. The class of ''G'' states (superposition of W and W) are shown to be optimally determined by just two (N-2)-partite marginals.

  7. Digital control system of a steam generator water level by LQG optimal method

    International Nuclear Information System (INIS)

    Lee, Yoon Joon

    1993-01-01

    A digital control system for the steam generator water level control is developed using LQG optimal design method. To describe the more realistic situaton, a feedwater valve actuator is assumed to be of the first order lagger and is included in the overall control system. By composing the digital control circuit in such a way that the overall control system consists of two sub-systems of feedwater station and feedback loop digital controller, the design procedure is divided into two independent steps. The feedwater station system is described in the error dynamics of an ordinary regulator system. The optimal gains are obtained by LQ method which imposes the constraints of the feedwater valve motion as well as on the output deviations. Developed also is a Kalman observer on account of the flow measurement uncertainty at low power. Then a digital controller on the feedback loop is designed so that the system maintains the same stability margins for all power ranges. The simulation results show thst the optimal digital system has a good control characteristics despite the adverse dynamics of a steam generator at low power. (Author)

  8. Medial prefrontal cortex and the adaptive regulation of reinforcement learning parameters.

    Science.gov (United States)

    Khamassi, Mehdi; Enel, Pierre; Dominey, Peter Ford; Procyk, Emmanuel

    2013-01-01

    Converging evidence suggest that the medial prefrontal cortex (MPFC) is involved in feedback categorization, performance monitoring, and task monitoring, and may contribute to the online regulation of reinforcement learning (RL) parameters that would affect decision-making processes in the lateral prefrontal cortex (LPFC). Previous neurophysiological experiments have shown MPFC activities encoding error likelihood, uncertainty, reward volatility, as well as neural responses categorizing different types of feedback, for instance, distinguishing between choice errors and execution errors. Rushworth and colleagues have proposed that the involvement of MPFC in tracking the volatility of the task could contribute to the regulation of one of RL parameters called the learning rate. We extend this hypothesis by proposing that MPFC could contribute to the regulation of other RL parameters such as the exploration rate and default action values in case of task shifts. Here, we analyze the sensitivity to RL parameters of behavioral performance in two monkey decision-making tasks, one with a deterministic reward schedule and the other with a stochastic one. We show that there exist optimal parameter values specific to each of these tasks, that need to be found for optimal performance and that are usually hand-tuned in computational models. In contrast, automatic online regulation of these parameters using some heuristics can help producing a good, although non-optimal, behavioral performance in each task. We finally describe our computational model of MPFC-LPFC interaction used for online regulation of the exploration rate and its application to a human-robot interaction scenario. There, unexpected uncertainties are produced by the human introducing cued task changes or by cheating. The model enables the robot to autonomously learn to reset exploration in response to such uncertain cues and events. The combined results provide concrete evidence specifying how prefrontal

  9. Protein Phosphotyrosine Phosphatase 1B (PTP1B) in Calpain-dependent Feedback Regulation of Vascular Endothelial Growth Factor Receptor (VEGFR2) in Endothelial Cells

    Science.gov (United States)

    Zhang, Yixuan; Li, Qiang; Youn, Ji Youn; Cai, Hua

    2017-01-01

    The VEGF/VEGFR2/Akt/eNOS/NO pathway is essential to VEGF-induced angiogenesis. We have previously discovered a novel role of calpain in mediating VEGF-induced PI3K/AMPK/Akt/eNOS activation through Ezrin. Here, we sought to identify possible feedback regulation of VEGFR2 by calpain via its substrate protein phosphotyrosine phosphatase 1B (PTP1B), and the relevance of this pathway to VEGF-induced angiogenesis, especially in diabetic wound healing. Overexpression of PTP1B inhibited VEGF-induced VEGFR2 and Akt phosphorylation in bovine aortic endothelial cells, while PTP1B siRNA increased both, implicating negative regulation of VEGFR2 by PTP1B. Calpain inhibitor ALLN induced VEGFR2 activation, which can be completely blocked by PTP1B overexpression. Calpain activation induced by overexpression or Ca/A23187 resulted in PTP1B cleavage, which can be blocked by ALLN. Moreover, calpain activation inhibited VEGF-induced VEGFR2 phosphorylation, which can be restored by PTP1B siRNA. These data implicate calpain/PTP1B negative feedback regulation of VEGFR2, in addition to the primary signaling pathway of VEGF/VEGFR2/calpain/PI3K/AMPK/Akt/eNOS. We next examined a potential role of PTP1B in VEGF-induced angiogenesis. Endothelial cells transfected with PTP1B siRNA showed faster wound closure in response to VEGF. Aortic discs isolated from PTP1B siRNA-transfected mice also had augmented endothelial outgrowth. Importantly, PTP1B inhibition and/or calpain overexpression significantly accelerated wound healing in STZ-induced diabetic mice. In conclusion, our data for the first time demonstrate a calpain/PTP1B/VEGFR2 negative feedback loop in the regulation of VEGF-induced angiogenesis. Modulation of local PTP1B and/or calpain activities may prove beneficial in the treatment of impaired wound healing in diabetes. PMID:27872190

  10. RISK AS AN OBJECT OF STATE REGULATION

    Directory of Open Access Journals (Sweden)

    Perfilyev A. A.

    2016-09-01

    Full Text Available The purpose of this article is to consider the possible mechanism of enterprise risk management from macroeconomic perspective. The need for investment risk management from the standpoint of the economy as a whole is determined by the following circumstances. Financial market conditions affecting the investment decisions of companies raises the financial markets in the category of the main sources of investment resources. This creates a state's interest in the effect on these sources, but it doesn't have effective ways to influence the investors’ decisions. Transition of regulator from influencing the cash flows to the regulation of investment activity creates a new paradigm for the financial management of the economy, which is based on a well-known fact that in the global economy the demand for goods and services is presented as a demand, mediated by investment decisions. The motives and mechanisms of investment decisions in a closed economy are well described by modern financial theory. In financial theory a mechanism of financial risk management is developed primarily from the standpoint of an investor, ignoring the problem in a broader context - within whole financial market of a country. Expanding the area of investment decisions international financial markets generate a need for new approaches to study of investment risks of corporations, which in this field are connected with country risk and should be considered as an object of state regulation. An analysis of fundamentals of the financial theory about the behavior of the investor, the state and the role of global financial markets in the choice of investors reveals that investment motives of corporations and mechanisms of regulators' influence on the cash flow are loosely bound in the matter of the volume of investments, which ones agree to implement, while others expect to receive. In our view, there is a need for a mechanism allowing the state to influence the investment decisions

  11. Homeostasis of exercise hyperpnea and optimal sensorimotor integration: the internal model paradigm.

    Science.gov (United States)

    Poon, Chi-Sang; Tin, Chung; Yu, Yunguo

    2007-10-15

    Homeostasis is a basic tenet of biomedicine and an open problem for many physiological control systems. Among them, none has been more extensively studied and intensely debated than the dilemma of exercise hyperpnea - a paradoxical homeostatic increase of respiratory ventilation that is geared to metabolic demands instead of the normal chemoreflex mechanism. Classical control theory has led to a plethora of "feedback/feedforward control" or "set point" hypotheses for homeostatic regulation, yet so far none of them has proved satisfactory in explaining exercise hyperpnea and its interactions with other respiratory inputs. Instead, the available evidence points to a far more sophisticated respiratory controller capable of integrating multiple afferent and efferent signals in adapting the ventilatory pattern toward optimality relative to conflicting homeostatic, energetic and other objectives. This optimality principle parsimoniously mimics exercise hyperpnea, chemoreflex and a host of characteristic respiratory responses to abnormal gas exchange or mechanical loading/unloading in health and in cardiopulmonary diseases - all without resorting to a feedforward "exercise stimulus". Rather, an emergent controller signal encoding the projected metabolic level is predicted by the principle as an exercise-induced 'mental percept' or 'internal model', presumably engendered by associative learning (operant conditioning or classical conditioning) which achieves optimality through continuous identification of, and adaptation to, the causal relationship between respiratory motor output and resultant chemical-mechanical afferent feedbacks. This internal model self-tuning adaptive control paradigm opens a new challenge and exciting opportunity for experimental and theoretical elucidations of the mechanisms of respiratory control - and of homeostatic regulation and sensorimotor integration in general.

  12. Pulsed klystrons with feedback controlled mod-anode modulators

    Energy Technology Data Exchange (ETDEWEB)

    Reass, William A [Los Alamos National Laboratory; Baca, David M [Los Alamos National Laboratory; Jerry, Davis L [Los Alamos National Laboratory; Rees, Daniel E [Los Alamos National Laboratory

    2009-01-01

    This paper describes a fast rise and fall, totem-pole mod-anode modulators for klystron application. Details of these systems as recently installed utilizing a beam switch tube ''on-deck'' and a planar triode ''off-deck'' in a grid-catch feedback regulated configuration will be provided. The grid-catch configuration regulates the klystron mod-anode voltage at a specified set-point during switching as well as providing a control mechanism that flat-top regulates the klystron beam current during the pulse. This flat-topped klystron beam current is maintained while the capacitor bank droops. In addition, we will review more modern on-deck designs using a high gain, high voltage planar triode as a regulating and switching element. These designs are being developed, tested, and implemented for the Los Alamos Neutron Science Center (LANSCE) accelerator refurbishment project, ''LANSCE-R''. An advantage of the planar triode is that the tube can be directly operated with solid state linear components and provides for a very compact design. The tubes are inexpensive compared to stacked semiconductor switching assemblies and also provide a linear control capability. Details of these designs are provided as well as operational and developmental results.

  13. Preliminary Study on Structural Optimization with Control Variables Using Equivalent Static Loads for Spring-damper Control Systems

    International Nuclear Information System (INIS)

    Yoo, Nam-sun; Jung, Ui-Jin; Park, Gyung-Jin; Kim, Tai-Kyung

    2014-01-01

    An optimization method is proposed for the simultaneous design of structural and control systems using the equivalent static loads. In the past researches, the control parameters of such feedback gains are obtained to improve some performance in the steady-state. However, the actuators which have position and velocity feedback gains should be designed to exhibit a good performance in the time domain. In other words, the system analysis should be conducted for the transient-state in dynamic manner. In this research, a new equivalent static loads method is presented to treat the control variables as the design variables. The equivalent static loads (ESLs) set is defined as a static load set which generates the same displacement field as that from dynamic loads at a certain time. The calculated sets of ESLs are applied as multiple loading conditions in the optimization process. Several examples are solved to validate the proposed method

  14. Time-delayed feedback technique for suppressing instabilities in time-periodic flow

    Science.gov (United States)

    Shaabani-Ardali, Léopold; Sipp, Denis; Lesshafft, Lutz

    2017-11-01

    A numerical method is presented that allows to compute time-periodic flow states, even in the presence of hydrodynamic instabilities. The method is based on filtering nonharmonic components by way of delayed feedback control, as introduced by Pyragas [Phys. Lett. A 170, 421 (1992), 10.1016/0375-9601(92)90745-8]. Its use in flow problems is demonstrated here for the case of a periodically forced laminar jet, subject to a subharmonic instability that gives rise to vortex pairing. The optimal choice of the filter gain, which is a free parameter in the stabilization procedure, is investigated in the context of a low-dimensional model problem, and it is shown that this model predicts well the filter performance in the high-dimensional flow system. Vortex pairing in the jet is efficiently suppressed, so that the unstable periodic flow state in response to harmonic forcing is accurately retrieved. The procedure is straightforward to implement inside any standard flow solver. Memory requirements for the delayed feedback control can be significantly reduced by means of time interpolation between checkpoints. Finally, the method is extended for the treatment of periodic problems where the frequency is not known a priori. This procedure is demonstrated for a three-dimensional cubic lid-driven cavity in supercritical conditions.

  15. Maintenance analysis method and operational feedback: a comprehensive maintenance management

    International Nuclear Information System (INIS)

    Mathieu Riou; Victor Planchon

    2006-01-01

    Full text of publication follows: Current periodic inspections program carried out on the COGEMA LOGISTICS casks is required by regulations and approved by the competent Authority. Thus, Safety and casks conformity to the according certificate of approval are guaranteed. Nonetheless, based on experience it appeared that some maintenance operations did not seem relevant or were redundant. Then, it was decided to rethink completely our maintenance program to reach the following objectives: - Set up the 'a minima' required inspection operations required to guarantee Safety and conformity to the certificate of approval, - Optimize criteria and periodicities of inspections taking into account: operational feedback, routine inspections carried out for each transport, regulations, environmental impact (ALARA, waste reduction,...), cost-effectiveness (reduction of cask's immobilization period,...). - Set up a maintenance program in Safety Analysis Reports that: stands alone (no need to check the specification or the certificate of approval to have the complete list of inspections mandatory to guarantee Safety), gives objectives instead of means of controls. This approach needs then to be re-evaluated by the competent Authority. Study's scope has been limited to the TN TM 12 cask family which is intensely used. COGEMA LOGISTICS has a high operational feedback on these casks. After Authority agreement, and in accordance with its requirements, study will then be extended to the other casks belonging to the COGEMA LOGISTICS cask fleet. Actually, the term 'maintenance' is linked to 'Base maintenance' and 'Main maintenance' and implicitly means that the cask is immobilized for a given period. To emphasize the modifications, the term 'maintenance' is no longer used and is substituted by 'periodic upkeep'. By changing the name, COGEMA LOGISTICS wants to emphasize that: some operations can for instance be realized while the cask is unloaded, periodicities are thought in terms of

  16. Feedback-Based Projected-Gradient Method For Real-Time Optimization of Aggregations of Energy Resources: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Dall-Anese, Emiliano [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Bernstein, Andrey [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Simonetto, Andrea [IBM Research Center Ireland

    2017-11-27

    This paper develops an online optimization method to maximize the operational objectives of distribution-level distributed energy resources (DERs) while adjusting the aggregate power generated (or consumed) in response to services requested by grid operators. The design of the online algorithm is based on a projected-gradient method, suitably modified to accommodate appropriate measurements from the distribution network and the DERs. By virtue of this approach, the resultant algorithm can cope with inaccuracies in the representation of the AC power, it avoids pervasive metering to gather the state of noncontrollable resources, and it naturally lends itself to a distributed implementation. Optimality claims are established in terms of tracking of the solution of a well-posed time-varying optimization problem.

  17. Computer-based formative assessment: variables influencing feedback behaviour

    NARCIS (Netherlands)

    Timmers, C.F.

    2013-01-01

    Assessment can be used to stimulate and direct student learning. This refers to the formative function of assessment. Formative assessments contribute to learning by generating feedback. Here, feedback is conceptualised as information about learners actual state of performance intended to modify

  18. Optimal allocation of sensors for state estimation of distributed parameter systems

    International Nuclear Information System (INIS)

    Sunahara, Yoshifumi; Ohsumi, Akira; Mogami, Yoshio.

    1978-01-01

    The purpose of this paper is to present a method for finding the optimal allocation of sensors for state estimation of linear distributed parameter systems. This method is based on the criterion that the error covariance associated with the state estimate becomes minimal with respect to the allocation of the sensors. A theorem is established, giving the sufficient condition for optimizing the allocation of sensors to make minimal the error covariance approximated by a modal expansion. The remainder of this paper is devoted to illustrate important phases of the general theory of the optimal measurement allocation problem. To do this, several examples are demonstrated, including extensive discussions on the mutual relation between the optimal allocation and the dynamics of sensors. (author)

  19. Influences of State and Trait Affect on Behavior, Feedback-Related Negativity, and P3b in the Ultimatum Game.

    Directory of Open Access Journals (Sweden)

    Korbinian Riepl

    Full Text Available The present study investigates how different emotions can alter social bargaining behavior. An important paradigm to study social bargaining is the Ultimatum Game. There, a proposer gets a pot of money and has to offer part of it to a responder. If the responder accepts, both players get the money as proposed by the proposer. If he rejects, none of the players gets anything. Rational choice models would predict that responders accept all offers above 0. However, evidence shows that responders typically reject a large proportion of all unfair offers. We analyzed participants' behavior when they played the Ultimatum Game as responders and simultaneously collected electroencephalogram data in order to quantify the feedback-related negativity and P3b components. We induced state affect (momentarily emotions unrelated to the task via short movie clips and measured trait affect (longer-lasting emotional dispositions via questionnaires. State happiness led to increased acceptance rates of very unfair offers. Regarding neurophysiology, we found that unfair offers elicited larger feedback-related negativity amplitudes than fair offers. Additionally, an interaction of state and trait affect occurred: high trait negative affect (subsuming a variety of aversive mood states led to increased feedback-related negativity amplitudes when participants were in an angry mood, but not if they currently experienced fear or happiness. We discuss that increased rumination might be responsible for this result, which might not occur, however, when people experience happiness or fear. Apart from that, we found that fair offers elicited larger P3b components than unfair offers, which might reflect increased pleasure in response to fair offers. Moreover, high trait negative affect was associated with decreased P3b amplitudes, potentially reflecting decreased motivation to engage in activities. We discuss implications of our results in the light of theories and research on

  20. Influences of State and Trait Affect on Behavior, Feedback-Related Negativity, and P3b in the Ultimatum Game.

    Science.gov (United States)

    Riepl, Korbinian; Mussel, Patrick; Osinsky, Roman; Hewig, Johannes

    2016-01-01

    The present study investigates how different emotions can alter social bargaining behavior. An important paradigm to study social bargaining is the Ultimatum Game. There, a proposer gets a pot of money and has to offer part of it to a responder. If the responder accepts, both players get the money as proposed by the proposer. If he rejects, none of the players gets anything. Rational choice models would predict that responders accept all offers above 0. However, evidence shows that responders typically reject a large proportion of all unfair offers. We analyzed participants' behavior when they played the Ultimatum Game as responders and simultaneously collected electroencephalogram data in order to quantify the feedback-related negativity and P3b components. We induced state affect (momentarily emotions unrelated to the task) via short movie clips and measured trait affect (longer-lasting emotional dispositions) via questionnaires. State happiness led to increased acceptance rates of very unfair offers. Regarding neurophysiology, we found that unfair offers elicited larger feedback-related negativity amplitudes than fair offers. Additionally, an interaction of state and trait affect occurred: high trait negative affect (subsuming a variety of aversive mood states) led to increased feedback-related negativity amplitudes when participants were in an angry mood, but not if they currently experienced fear or happiness. We discuss that increased rumination might be responsible for this result, which might not occur, however, when people experience happiness or fear. Apart from that, we found that fair offers elicited larger P3b components than unfair offers, which might reflect increased pleasure in response to fair offers. Moreover, high trait negative affect was associated with decreased P3b amplitudes, potentially reflecting decreased motivation to engage in activities. We discuss implications of our results in the light of theories and research on depression and