WorldWideScience

Sample records for opportunity models

  1. Computer Aided ModellingOpportunities and Challenges

    DEFF Research Database (Denmark)

    Cameron, Ian; Gani, Rafiqul

    2011-01-01

    -based solutions to significant problems? The important issues of workflow and data flow are discussed together with fit-for-purpose model development. As well, the lack of tools around multiscale modelling provides opportunities for the development of efficient tools to address such challenges. The ability......This chapter considers the opportunities that are present in developing, extending and applying aspects of computer-aided modelling principles and practice. What are the best tasks to be done by modellers and what needs the application of CAPE tools? How do we efficiently develop model...... and opportunities are discussed for such systems....

  2. Computer Aided ModellingOpportunities and Challenges

    DEFF Research Database (Denmark)

    2011-01-01

    This chapter considers the opportunities that are present in developing, extending and applying aspects of computer-aided modelling principles and practice. What are the best tasks to be done by modellers and what needs the application of CAPE tools? How do we efficiently develop model-based solu......This chapter considers the opportunities that are present in developing, extending and applying aspects of computer-aided modelling principles and practice. What are the best tasks to be done by modellers and what needs the application of CAPE tools? How do we efficiently develop model...

  3. Challenges and Opportunities in Analysing Students Modelling

    Science.gov (United States)

    Blanco-Anaya, Paloma; Justi, Rosária; Díaz de Bustamante, Joaquín

    2017-01-01

    Modelling-based teaching activities have been designed and analysed from distinct theoretical perspectives. In this paper, we use one of them--the model of modelling diagram (MMD)--as an analytical tool in a regular classroom context. This paper examines the challenges that arise when the MMD is used as an analytical tool to characterise the…

  4. Opportunities of probabilistic flood loss models

    Science.gov (United States)

    Schröter, Kai; Kreibich, Heidi; Lüdtke, Stefan; Vogel, Kristin; Merz, Bruno

    2016-04-01

    Oftentimes, traditional uni-variate damage models as for instance depth-damage curves fail to reproduce the variability of observed flood damage. However, reliable flood damage models are a prerequisite for the practical usefulness of the model results. Innovative multi-variate probabilistic modelling approaches are promising to capture and quantify the uncertainty involved and thus to improve the basis for decision making. In this study we compare the predictive capability of two probabilistic modelling approaches, namely Bagging Decision Trees and Bayesian Networks and traditional stage damage functions. For model evaluation we use empirical damage data which are available from computer aided telephone interviews that were respectively compiled after the floods in 2002, 2005, 2006 and 2013 in the Elbe and Danube catchments in Germany. We carry out a split sample test by sub-setting the damage records. One sub-set is used to derive the models and the remaining records are used to evaluate the predictive performance of the model. Further we stratify the sample according to catchments which allows studying model performance in a spatial transfer context. Flood damage estimation is carried out on the scale of the individual buildings in terms of relative damage. The predictive performance of the models is assessed in terms of systematic deviations (mean bias), precision (mean absolute error) as well as in terms of sharpness of the predictions the reliability which is represented by the proportion of the number of observations that fall within the 95-quantile and 5-quantile predictive interval. The comparison of the uni-variable Stage damage function and the multivariable model approach emphasises the importance to quantify predictive uncertainty. With each explanatory variable, the multi-variable model reveals an additional source of uncertainty. However, the predictive performance in terms of precision (mbe), accuracy (mae) and reliability (HR) is clearly improved

  5. Traffic Congestion Model: Challenges and Opportunities

    Science.gov (United States)

    Enjat Munajat, M. D.; Munir, Rinaldi; Widyantoro, Dwi H.

    2017-01-01

    This paper discusses models to detect traffic congestion using two approaches: road detection and moving object detection. There are two methods proposed to detect roads and moving objects. The methods involve the detection of both moving and non-moving objects. The system presented in this paper is able to detect roads as well as moving objects. However, further development is needed to detect extreme road curves. The system presented in this paper is relatively inexpensive since it only uses one camera and capable of capturing satisfactorily detailed images.

  6. Creating opportunities to influence self-efficacy through modeling instruction

    Science.gov (United States)

    Sawtelle, Vashti; Brewe, Eric; Goertzen, Renee Michelle; Kramer, Laird H.

    2012-02-01

    In this paper we present an initial analysis connecting key elements of Modeling Instruction (MI) to self-efficacy experience opportunities. Previously, we demonstrated that MI has positive effects on self-efficacy when compared with traditional Lecture instruction [1]. We also found a particularly strong positive effect on the social persuasion source of self-efficacy for women in the MI class. Our current study seeks to understand through what mechanisms MI influences self-efficacy. We demonstrate this connection through an in-depth analysis of video chosen to exemplify Modeling techniques used in a problem-solving episode by three female participants enrolled in a MI introductory physics class. We provide a rich and descriptive analysis of the self-efficacy experiences opportunities within this context and discuss how these opportunities provide a potential explanation of how MI influences self-efficacy.

  7. Projected Statewide Impact of "Opportunity Culture" School Models

    Science.gov (United States)

    Holly, Christen; Dean, Stephanie; Hassel, Emily Ayscue; Hassel, Bryan C.

    2014-01-01

    This brief estimates the impact of a statewide implementation of Opportunity Culture models, using North Carolina as an example. Impacts estimated include student learning outcomes, gross state product, teacher pay, and other career characteristics, and state income tax revenue. Estimates indicate the potential for a statewide transition to…

  8. Model Based Mission Assurance: Emerging Opportunities for Robotic Systems

    Science.gov (United States)

    Evans, John W.; DiVenti, Tony

    2016-01-01

    The emergence of Model Based Systems Engineering (MBSE) in a Model Based Engineering framework has created new opportunities to improve effectiveness and efficiencies across the assurance functions. The MBSE environment supports not only system architecture development, but provides for support of Systems Safety, Reliability and Risk Analysis concurrently in the same framework. Linking to detailed design will further improve assurance capabilities to support failures avoidance and mitigation in flight systems. This also is leading new assurance functions including model assurance and management of uncertainty in the modeling environment. Further, the assurance cases, a structured hierarchal argument or model, are emerging as a basis for supporting a comprehensive viewpoint in which to support Model Based Mission Assurance (MBMA).

  9. A Newsvendor Model with Initial Inventory and Two Salvage Opportunities

    Directory of Open Access Journals (Sweden)

    Ali Cheaitou

    2011-06-01

    Full Text Available In this paper, we develop an extension of the newsvendor model with initial inventory. In addition to the usual quantity ordered at the beginning of the horizon and the usual quantity salvaged at the end of the horizon, we introduce a new decision variable: a salvage opportunity at the beginning of the horizon, which might be used in the case of high initial inventory level. We develop the expression of the optimal policy for this extended model, for a general demand distribution. The structure of this optimal policy is particular and is characterized by two threshold levels. Some managerial insights are given via numerical examples.

  10. Seasonal forecasting and health impact models: challenges and opportunities.

    Science.gov (United States)

    Ballester, Joan; Lowe, Rachel; Diggle, Peter J; Rodó, Xavier

    2016-10-01

    After several decades of intensive research, steady improvements in understanding and modeling the climate system have led to the development of the first generation of operational health early warning systems in the era of climate services. These schemes are based on collaborations across scientific disciplines, bringing together real-time climate and health data collection, state-of-the-art seasonal climate predictions, epidemiological impact models based on historical data, and an understanding of end user and stakeholder needs. In this review, we discuss the challenges and opportunities of this complex, multidisciplinary collaboration, with a focus on the factors limiting seasonal forecasting as a source of predictability for climate impact models. © 2016 New York Academy of Sciences.

  11. Challenges and opportunities for integrating lake ecosystem modelling approaches

    Science.gov (United States)

    Mooij, Wolf M.; Trolle, Dennis; Jeppesen, Erik; Arhonditsis, George; Belolipetsky, Pavel V.; Chitamwebwa, Deonatus B.R.; Degermendzhy, Andrey G.; DeAngelis, Donald L.; Domis, Lisette N. De Senerpont; Downing, Andrea S.; Elliott, J. Alex; Ruberto, Carlos Ruberto; Gaedke, Ursula; Genova, Svetlana N.; Gulati, Ramesh D.; Hakanson, Lars; Hamilton, David P.; Hipsey, Matthew R.; Hoen, Jochem 't; Hulsmann, Stephan; Los, F. Hans; Makler-Pick, Vardit; Petzoldt, Thomas; Prokopkin, Igor G.; Rinke, Karsten; Schep, Sebastiaan A.; Tominaga, Koji; Van Dam, Anne A.; Van Nes, Egbert H.; Wells, Scott A.; Janse, Jan H.

    2010-01-01

    A large number and wide variety of lake ecosystem models have been developed and published during the past four decades. We identify two challenges for making further progress in this field. One such challenge is to avoid developing more models largely following the concept of others ('reinventing the wheel'). The other challenge is to avoid focusing on only one type of model, while ignoring new and diverse approaches that have become available ('having tunnel vision'). In this paper, we aim at improving the awareness of existing models and knowledge of concurrent approaches in lake ecosystem modelling, without covering all possible model tools and avenues. First, we present a broad variety of modelling approaches. To illustrate these approaches, we give brief descriptions of rather arbitrarily selected sets of specific models. We deal with static models (steady state and regression models), complex dynamic models (CAEDYM, CE-QUAL-W2, Delft 3D-ECO, LakeMab, LakeWeb, MyLake, PCLake, PROTECH, SALMO), structurally dynamic models and minimal dynamic models. We also discuss a group of approaches that could all be classified as individual based: super-individual models (Piscator, Charisma), physiologically structured models, stage-structured models and trait-based models. We briefly mention genetic algorithms, neural networks, Kalman filters and fuzzy logic. Thereafter, we zoom in, as an in-depth example, on the multi-decadal development and application of the lake ecosystem model PCLake and related models (PCLake Metamodel, Lake Shira Model, IPH-TRIM3D-PCLake). In the discussion, we argue that while the historical development of each approach and model is understandable given its 'leading principle', there are many opportunities for combining approaches. We take the point of view that a single 'right' approach does not exist and should not be strived for. Instead, multiple modelling approaches, applied concurrently to a given problem, can help develop an integrative

  12. Network models of frugivory and seed dispersal: Challenges and opportunities

    Science.gov (United States)

    Carlo, Tomás A.; Yang, Suann

    2011-11-01

    Network analyses have emerged as a new tool to study frugivory and seed dispersal (FSD) mutualisms because networks can model and simplify the complexity of multiple community-wide species interactions. Moreover, network theory suggests that structural properties, such as the presence of highly generalist species, are linked to the stability of mutualistic communities. However, we still lack empirical validation of network model predictions. Here we outline new research avenues to connect network models to FSD processes, and illustrate the challenges and opportunities of this tool with a field study. We hypothesized that generalist frugivores would be important for forest stability by dispersing seeds into deforested areas and initiating reforestation. We then constructed a network of plant-frugivore interactions using published data and identified the most generalist frugivores. To test the importance of generalists we measured: 1) the frequency with which frugivores moved between pasture and forest, 2) the bird-generated seed rain under perches in the pasture, and 3) the perching frequency of birds above seed traps. The generalist frugivores in the forest network were not important for seed dispersal into pastures, and thus for forest recovery, because the forest network excluded habitat heterogeneities, frugivore behavior, and movements. More research is needed to develop ways to incorporate relevant FSD processes into network models in order for these models to be more useful to community ecology and conservation. The network framework can serve to spark and renew interest in FSD and further our understanding of plant-animal communities.

  13. Tramp Ship Routing and Scheduling - Models, Methods and Opportunities

    DEFF Research Database (Denmark)

    Vilhelmsen, Charlotte; Larsen, Jesper; Lusby, Richard Martin

    and scheduling. This includes a review on existing literature, modelling approaches, solution methods as well as an analysis of the current status and future opportunities of research within tramp ship routing and scheduling. We argue that rather than developing new solution methods for the basic routing...... to mergers, pooling, and collaboration efforts between shipping companies, the fleet sizes have grown to a point where manual planning is no longer adequate in a market with tough competition and low freight rates. The aim of this paper is to provide a comprehensive introduction to tramp ship routing...... and scheduling problem, focus should now be on extending this basic problem to include additional real-world complexities and develop suitable solution methods for those extensions. Such extensions will enable more tramp operators to benefit from the solution methods while simultaneously creating new...

  14. Integrative biological systems modeling:challenges and opportunities

    Institute of Scientific and Technical Information of China (English)

    Jialiang WU; Eberhard VOIT

    2009-01-01

    Most biological systems are by nature hybrids consist of interacting discrete and continuous components,which may even operate on different time scales. Therefore," it is desirable to establish modeling frameworks that are capable of combining deterministic and stochastic, discrete and continuous, as well as multi-timescale features. In the context of molecular systems biology, an example for the need of such a combination is the investigation of integrated biological pathways that contain gene regulatory, metabolic and signaling components, which may operate on different time scales and involve on-off switches as well as stochastic effects. The implementation of integrated hybrid systems is not trivial because most software is limited to one or the other of the dichotomies above. In this study, we first review the motivation for hybrid modeling. Secondly, by using the example of a toggle switch model, we illustrate a recently developed modeling framework that is based on the combination of biochemical systems theory (BST) and hybrid functional Petri nets (HFPN). Finally, we discuss remaining challenges and future opportunities.

  15. Elite and Status Attainment Models of Inequality of Opportunity

    Science.gov (United States)

    Myles, John F.; Srensen, Aage B.

    1975-01-01

    With changes in method, analysis of the process of attainment of various occupations and sub-sets of occupations such as elites can bring about the desired comparability between elite and status attainment studies of equality of opportunity. (Author/AM)

  16. Social entrepreneurship in China: models, dynamics, challenges and opportunities

    OpenAIRE

    Kang, Mengqi

    2015-01-01

    Social entrepreneurship (SE) has been one of the most rapidly developing concepts among the academic world and also in society. Its significance could be partly explained by the fact that traditional non-profits and philanthropy have not been successful in solving some of the world's major social problems. However, there seems to be a void in China's position in the topic while in fact China seems to be a land full of opportunities for SE undertakings: while experiencing rapid economic develo...

  17. Developing a Creative-Cognitive Model of Entrepreneurial Alertness to Business Opportunities

    OpenAIRE

    Vesa Puhakka

    2011-01-01

    A creative-cognitive perspective is used in this study to explore alertness to business opportunities in order to develop a model of business opportunity recognition. It is assumed that the elements constituting this opportunity creation are entrepreneur¡¯s creative cognitive process, internal creative qualities, environmental conditions supporting or hindering creativity and interaction of these elements, and that they have a significant impact on the innovativeness of the business opportuni...

  18. Challenges and opportunities for integrating lake ecosystem modelling approaches

    NARCIS (Netherlands)

    Mooij, W.M.; Trolle, D.; Jeppesen, E.; Arhonditsis, G.; Belolipetsky, P.; Chitamwebwa, D.B.R.; Degermendzhy, A.G.; DeAngelis, D.L.; De Senerpont Domis, L.N.; Downing, A.S.; Elliott, J.A.; Fragoso Jr., C.R.; Gaedke, U.; Genova, S.N.; Gulati, R.D.; Håkanson, L.; Hamilton, D.P.; Hipsey, M.R.; ‘t Hoen, P.J.; Hülsmann, S.; Los, F.J.; Makler-Pick, V.; Petzoldt, T.; Prokopkin, I.; Rinke, K.; Schep, S.A.; Tominaga, K.; Van Dam, A.A.; van Nes, E.H.; Wells, S.A.; Janse, J.H.

    2010-01-01

    A large number and wide variety of lake ecosystem models have been developed and published during the past four decades. We identify two challenges for making further progress in this field. One such challenge is to avoid developing more models largely following the concept of others (‘reinventing t

  19. Challenges and opportunities for integrating lake ecosystem modelling approaches

    NARCIS (Netherlands)

    Mooij, W.M.; Trolle, D.; Jeppesen, E.; Arhonditsis, G.; Belolipetsky, P.V.; Chitamwebwa, D.B.R.; Degermendzhy, A.G.; DeAngelis, D.L.; Domis, L.N.D.; Downing, A.S.; Elliott, J.A.; Fragoso, C.R.; Gaedke, U.; Genova, S.N.; Gulati, R.D.; Hakanson, L.; Hamilton, D.P.; Hipsey, M.R.; Hoen, 't J.; Hulsmann, S.; Los, F.H.; Makler-Pick, V.; Petzoldt, T.; Prokopkin, I.G.; Rinke, K.; Schep, S.A.; Tominaga, K.; Dam, van A.A.; Nes, van E.H.; Wells, S.A.; Janse, J.H.

    2010-01-01

    A large number and wide variety of lake ecosystem models have been developed and published during the past four decades. We identify two challenges for making further progress in this field. One such challenge is to avoid developing more models largely following the concept of others ('reinventing t

  20. Modeling root water uptake in soils: opportunities and challenges

    Science.gov (United States)

    Javaux, Mathieu; Couvreur, Valentin; Huber, Katrin; Meunier, Félicien; Vanderborght, Jan; Vereecken, Harry

    2016-04-01

    Root water uptake modeling concepts have evolved over time. On one hand, mesoscopic models have been developed, which explicitly represent the fluxes at the soil root interfaces. On the other hand macroscopic approaches were proposed, which embedded root water uptake into a sink term in the macroscopic mass balance equation. Today, new techniques for imaging root architecture, water fluxes and soil properties open new possibilities to the understanding of water depletion in planted soils. Amongst others, architectural hydraulic root and soil models can be used to bridge the scale gap between single root and plant scales. In this talk, several new promising experimental approaches will be presented together with new models and upscaling procedures, possibly paving the way for the future models of root water uptake. Furthermore, open challenges will also be presented.

  1. 4Mx Soil-Plant Model: Applications, Opportunities and Challenges

    Directory of Open Access Journals (Sweden)

    Nándor Fodor

    2012-12-01

    Full Text Available Crop simulation models describe the main processes of the soil-plant system in a dynamic way usually in a daily time-step. With the help of these models we may monitor the soil- and plant-related processes of the simulated system as they evolve according to the atmospheric and environmental conditions. Crop models could be successfully applied in the following areas: (1 Education: by promoting the system-oriented thinking a comprehensive overview of the interrelations of the soil-plant system as well as of the environmental protection related aspects of the human activities could be presented. (2 Research: The results of observations as well as of experiments could be extrapolated in time and space, thus, for example, the possible effects of the global climate change could be estimated. (3 Practice: Model calculations could be used in intelligent irrigation control and decision supporting systems as well as for providing scientific background for policy makers. The most spectacular feature of the 4Mx crop model is that its graphical user interface enables the user to alter not only the parameters of the model but the function types of its governing equations as well. The applicability of the 4Mx model is presented via several case-studies.

  2. Rodent models in Down syndrome research: impact and future opportunities.

    Science.gov (United States)

    Herault, Yann; Delabar, Jean M; Fisher, Elizabeth M C; Tybulewicz, Victor L J; Yu, Eugene; Brault, Veronique

    2017-10-01

    Down syndrome is caused by trisomy of chromosome 21. To date, a multiplicity of mouse models with Down-syndrome-related features has been developed to understand this complex human chromosomal disorder. These mouse models have been important for determining genotype-phenotype relationships and identification of dosage-sensitive genes involved in the pathophysiology of the condition, and in exploring the impact of the additional chromosome on the whole genome. Mouse models of Down syndrome have also been used to test therapeutic strategies. Here, we provide an overview of research in the last 15 years dedicated to the development and application of rodent models for Down syndrome. We also speculate on possible and probable future directions of research in this fast-moving field. As our understanding of the syndrome improves and genome engineering technologies evolve, it is necessary to coordinate efforts to make all Down syndrome models available to the community, to test therapeutics in models that replicate the whole trisomy and design new animal models to promote further discovery of potential therapeutic targets. © 2017. Published by The Company of Biologists Ltd.

  3. Key Challenges and Potential Urban Modelling Opportunities in ...

    African Journals Online (AJOL)

    Chris Wray

    monitoring and guiding urban spatial planning and development. ... and social system functions, urban modelling has evolved from simple ... careful long-term planning aligned with the national vision and other strategic perspectives' (GPC,.

  4. Advanced parallel programming models research and development opportunities.

    Energy Technology Data Exchange (ETDEWEB)

    Wen, Zhaofang.; Brightwell, Ronald Brian

    2004-07-01

    There is currently a large research and development effort within the high-performance computing community on advanced parallel programming models. This research can potentially have an impact on parallel applications, system software, and computing architectures in the next several years. Given Sandia's expertise and unique perspective in these areas, particularly on very large-scale systems, there are many areas in which Sandia can contribute to this effort. This technical report provides a survey of past and present parallel programming model research projects and provides a detailed description of the Partitioned Global Address Space (PGAS) programming model. The PGAS model may offer several improvements over the traditional distributed memory message passing model, which is the dominant model currently being used at Sandia. This technical report discusses these potential benefits and outlines specific areas where Sandia's expertise could contribute to current research activities. In particular, we describe several projects in the areas of high-performance networking, operating systems and parallel runtime systems, compilers, application development, and performance evaluation.

  5. A Multi-Objective Model for Planning Equal Employment Opportunities. Research Report No. 23. Revised Edition.

    Science.gov (United States)

    Charnes, A.; And Others

    The document suggests some new modeling approcaches for equal employment opportunity (EEO) planning. Previous manpower planning models of the Office of Civilian Manpower Management have utilized multi-period Markoff processes embedded in goal programing (multiple objective) models. These are here extended to EEO plans directed to changing the mix…

  6. Biofuels and water quality: challenges and opportunities for simulation modeling

    Energy Technology Data Exchange (ETDEWEB)

    Engel, Bernard A. [Purdue University; Chaubey, Indrajeet [Purdue University; Thomas, Mark [Purdue University; Saraswat, Dharmendra [University of Arkansas; Murphy, Patrick [Purdue University; Bhaduri, Budhendra L [ORNL

    2010-01-01

    Quantification of the various impacts of biofuel feedstock production on hydrology and water quality is complex. Mathematical models can be used to efficiently evaluate various what if scenarios related to biofeedstock production and their impacts on hydrology and water quality at various spatial and temporal scales. Currently available models, although having the potential to serve such purposes, have many limitations. In this paper, we review the strengths and weaknesses of such models in light of short- and long term biofeedstock production scenarios. The representation of processes in the currently available models and how these processes need to be modified to fully evaluate various complex biofeedstock production scenarios are discussed. Similarly, issues related to availability of data that are needed to parameterize and evaluate these models are presented. We have presented a vision for the development of decision support tools and ecosystem services that can be used to make watershed management decisions to minimize any potentially adverse environmental impacts while meeting biofeedstock demands. We also discuss a case study of biofeedstock impact simulation in relation to watershed management policy implications for various state and federal agencies in the USA.

  7. Master Data Management Model in Company: Challenges and Opportunity

    Directory of Open Access Journals (Sweden)

    Indrajani

    2015-12-01

    Full Text Available The purpose of this research is to analyze, design, and implement Master Data Management (MDM model for company, which include database processing that will be used in the quality of data customer and produce single view of customer. The research method used is literature study from a variety of journals, books, e-books, and articles on the internet. Also, fact finding techniques are done, such as by analyze, collect, and examine the documents, interviews, and observations. Then, other research methods used to analyze and design MDM model are using cleansing and matching technique. The result obtained from this research is an implementation MDM model for the company, where if implemented, will improve the quality of data significantly. The conclusion which can be obtained from this research is that MDM is one of the factors that can improve the quality of customer data.

  8. Modeling NSCLC Progression: Recent Advances and Opportunities Available

    OpenAIRE

    Suleiman, Ahmed Abbas; Nogova, Lucia; Fuhr, Uwe, 1960-

    2013-01-01

    Non-small cell lung cancer (NSCLC) is one of the leading causes of death around the world with an estimated 5-year relative survival rate of 16% at diagnosis. Development of drugs treating NSCLC is not easy, and the success rate for an anticancer treatment to pass through the whole clinical development process is as low as 5%. Modeling and simulation lend themselves as tools which can potentially streamline drug development. A critical component of the models developed is a description of how...

  9. Specialty Payment Model Opportunities and Assessment: Oncology Simulation Report.

    Science.gov (United States)

    White, Chapin; Chan, Chris; Huckfeldt, Peter J; Kofner, Aaron; Mulcahy, Andrew W; Pollak, Julia; Popescu, Ioana; Timbie, Justin W; Hussey, Peter S

    2015-07-15

    This article describes the results of a simulation analysis of a payment model for specialty oncology services that is being developed for possible testing by the Center for Medicare and Medicaid Innovation at the Centers for Medicare & Medicaid Services (CMS). CMS asked MITRE and RAND to conduct simulation analyses to preview some of the possible impacts of the payment model and to inform design decisions related to the model. The simulation analysis used an episode-level dataset based on Medicare fee-for-service (FFS) claims for historical oncology episodes provided to Medicare FFS beneficiaries in 2010. Under the proposed model, participating practices would continue to receive FFS payments, would also receive per-beneficiary per-month care management payments for episodes lasting up to six months, and would be eligible for performance-based payments based on per-episode spending for attributed episodes relative to a per-episode spending target. The simulation offers several insights into the proposed payment model for oncology: (1) The care management payments used in the simulation analysis-$960 total per six-month episode-represent only 4 percent of projected average total spending per episode (around $27,000 in 2016), but they are large relative to the FFS revenues of participating oncology practices, which are projected to be around $2,000 per oncology episode. By themselves, the care management payments would increase physician practices' Medicare revenues by roughly 50 percent on average. This represents a substantial new outlay for the Medicare program and a substantial new source of revenues for oncology practices. (2) For the Medicare program to break even, participating oncology practices would have to reduce utilization and intensity by roughly 4 percent. (3) The break-even point can be reduced if the care management payments are reduced or if the performance-based payments are reduced.

  10. Business models and opportunities for cancer vaccine developers.

    Science.gov (United States)

    Kudrin, Alex

    2012-10-01

    Despite of growing oncology pipeline, cancer vaccines contribute only to a minor share of total oncology-attributed revenues. This is mainly because of a limited number of approved products and limited sales from products approved under compassionate or via early access entry in smaller and less developed markets. However revenue contribution from these products is extremely limited and it remains to be established whether developers are breaking even or achieving profitability with existing sales. Cancer vaccine field is well recognized for high development costs and risks, low historical rates of investment return and high probability of failures arising in ventures, partnerships and alliances. The cost of reimbursement for new oncology agents is not universally acceptable to payers limiting the potential for a global expansion, market access and reducing probability of commercial success. In addition, the innovation in cancer immunotherapy is currently focused in small and mid-size biotech companies and academic institutions struggling for investment. Existing R&D innovation models are deemed unsustainable in current "value-for-money" oriented healthcare environment. New business models should be much more open to collaborative, networked and federated styles, which could help to outreach global, markets and increase cost-efficiencies across an entire value chain. Lessons learned from some developing countries and especially from South Korea illustrate that further growth of cancer vaccine industry will depends not only on new business models but also will heavily rely on regional support and initiatives from different bodies, such as governments, payers and regulatory bodies.

  11. Dental Care Coverage and Use: Modeling Limitations and Opportunities

    Science.gov (United States)

    Moeller, John F.; Chen, Haiyan

    2014-01-01

    Objectives. We examined why older US adults without dental care coverage and use would have lower use rates if offered coverage than do those who currently have coverage. Methods. We used data from the 2008 Health and Retirement Study to estimate a multinomial logistic model to analyze the influence of personal characteristics in the grouping of older US adults into those with and those without dental care coverage and dental care use. Results. Compared with persons with no coverage and no dental care use, users of dental care with coverage were more likely to be younger, female, wealthier, college graduates, married, in excellent or very good health, and not missing all their permanent teeth. Conclusions. Providing dental care coverage to uninsured older US adults without use will not necessarily result in use rates similar to those with prior coverage and use. We have offered a model using modifiable factors that may help policy planners facilitate programs to increase dental care coverage uptake and use. PMID:24328635

  12. Multimillion-cell SAGD models, opportunity for detailed field analysis

    Energy Technology Data Exchange (ETDEWEB)

    Akram, F. [Schlumberger Canada Limited (Canada)

    2011-07-01

    In the heavy oil industry, steam assisted gravity drainage (SAGD) is a new thermal oil recovery process used to enhance oil recovery. However, operators have trouble reaching their objectives. A better understanding of reservoir response is necessary to reach the desired production rates. The aim of this paper is to present a new methodology for carrying out a reservoir simulation study. A multimillion-cell model was developed with realistic properties, structural complexity and heterogeneities; both full field and thermal simulations were conducted. Results showed that the computing technology thus developed offers greater accuracy in less time than is required when using conventional techniques. In addition, this methodology provides a higher degree of confidence in the results by bridging the gap between geology and engineering. The paper is a first step in producing a framework and the methodology presented herein will need to be further tested to confirm its benefits over conventional techniques.

  13. The Opportunities and Challenges of Persuasive Technology in Creating Sustainable Innovation and Business Model Innovation

    DEFF Research Database (Denmark)

    Aagaard, Annabeth; Lindgren, Peter

    2015-01-01

    The opportunities of persuasive technology in facilitating sustainable innovation and business model innovation have been witnessed continuously during the last decade. The unique ability of persuasive technology in interacting and mediating across users, customers, decisions makers and other...... stakeholders provides access to core knowledge about behavior and opportunities to influence and even change their behavior in a positive and more sustainable manner. Sustainable innovation and business model innovation is gaining more and more competitive leverage due to customer requirements, the growing......-focused sustainable innovation and business model innovation, which is explored through a theoretical review and case examples in the present study. The findings reveal a number of key opportunities to pursue and a number of critical challenges to adjust to as presented in propositions....

  14. Digital Dividend Aware Business Models for the Creative Industries: Challenges and Opportunities in EU Markets

    Science.gov (United States)

    Cossiavelou, Vassiliki

    EU counties have a historically unique opportunity to enable their creative industries to promote the knowledge societies, applying new business models to their media content and networks markets, that are digital dividend (DD) aware. This new extra-media gatekeeping factor could shape new alliances and co operations among the member states and the global media markets, as well.

  15. Online communication among adolescents: An integrated model on its attraction, opportunities, and risks.

    NARCIS (Netherlands)

    Valkenburg, P.M.; Peter, J.

    2011-01-01

    Adolescents far outnumber adults in their use of e-communication technologies, such as instant messaging and social network sites. In this article, we present an integrative model that helps us to understand both the appeal of these technologies and their risks and opportunities for the psychosocial

  16. Opportunities for improved risk assessments of exotic species in Canada using bioclimatic modeling.

    Science.gov (United States)

    McKenney, Daniel W; Hopkin, Anthony A; Campbell, Kathy L; Mackey, Brendan G; Foottit, Robert

    2003-01-01

    This paper briefly reviews the process of exotic pest risk assessments and presents some examples of emerging opportunities for spatial bioclimatic modeling of exotic species in Canada. This type of analysis can support risk assessments but does not replace the need for on-going high quality field-based observations to validate and update models. Bioclimatic analysis of several exotic pests is provided to illustrate both opportunities and limits. A link is demonstrated to the National Forest Inventory to characterize timber volumes at risk for one exotic species. 'Challenges' are both scientific and administrative. More accessible and current field survey data are required to improve models. Our experience is that for many exotic species, historical, and even current, data are not always digital or quality controlled for taxonomic identity and accurate geo-referencing. This inhibits their use for integrated spatial modeling applications.

  17. BIG DATA-Related Challenges and Opportunities in Earth System Modeling

    Science.gov (United States)

    Bamzai, A. S.

    2012-12-01

    Knowledge of the Earth's climate has increased immensely in recent decades, both through observational analysis and modeling. BIG DATA-related challenges emerge in our quest for understanding the variability and predictability of the climate and earth system on a range of time scales, as well as in our endeavor to improve predictive capability using state-of-the-science models. To enable further scientific discovery, bottlenecks in current paradigms need to be addressed. An overview of current NSF activities in Earth System Modeling with a focus on associated data-related challenges and opportunities, will be presented.

  18. Recycled Bricks: Exploring Opportunities to Reintegrate Returning American Foreign Fighters Using Existing Models

    Science.gov (United States)

    2016-12-01

    working conditions ( teamwork and working with people they respect), external incentives (money for education and good pay), patriotic adventure...opportunity for adventure and doing something for their country), and equal opportunity (employment opportunities and harassment-free workplace for...opportunities, such as employment opportunities and especially for women and minorities, a harassment-free workplace . While employment is not a primary

  19. US Clean Energy Sector and the Opportunity for Modeling and Simulation

    Science.gov (United States)

    Inge, Carole Cameron

    2011-01-01

    The following paper sets forth the current understanding of the US clean energy demand and opportunity. As clean energy systems come online and technology is developed, modeling and simulation of these complex energy programs provides an untapped business opportunity. The US Department of Defense provides a great venue for developing new technology in the energy sector because it is demanding lower fuel costs, more energy efficiencies in its buildings and bases, and overall improvements in its carbon footprint. These issues coupled with the security issues faced by foreign dependence on oil will soon bring more clean energy innovations to the forefront (lighter batteries for soldiers, alternative fuel for jets, energy storage systems for ships, etc).

  20. Hurricane Loss Estimation Models: Opportunities for Improving the State of the Art.

    Science.gov (United States)

    Watson, Charles C., Jr.; Johnson, Mark E.

    2004-11-01

    The results of hurricane loss models are used regularly for multibillion dollar decisions in the insurance and financial services industries. These models are proprietary, and this “black box” nature hinders analysis. The proprietary models produce a wide range of results, often producing loss costs that differ by a ratio of three to one or more. In a study for the state of North Carolina, 324 combinations of loss models were analyzed, based on a combination of nine wind models, four surface friction models, and nine damage models drawn from the published literature in insurance, engineering, and meteorology. These combinations were tested against reported losses from Hurricanes Hugo and Andrew as reported by a major insurance company, as well as storm total losses for additional storms. Annual loss costs were then computed using these 324 combinations of models for both North Carolina and Florida, and compared with publicly available proprietary model results in Florida. The wide range of resulting loss costs for open, scientifically defensible models that perform well against observed losses mirrors the wide range of loss costs computed by the proprietary models currently in use. This outcome may be discouraging for governmental and corporate decision makers relying on this data for policy and investment guidance (due to the high variability across model results), but it also provides guidance for the efforts of future investigations to improve loss models. Although hurricane loss models are true multidisciplinary efforts, involving meteorology, engineering, statistics, and actuarial sciences, the field of meteorology offers the most promising opportunities for improvement of the state of the art.

  1. Density functional theory and beyond-opportunities for quantum methods in materials modeling semiconductor technology.

    Science.gov (United States)

    Shankar, Sadasivan; Simka, Harsono; Haverty, Michael

    2008-02-13

    In the semiconductor industry, the use of new materials has been increasing with the advent of nanotechnology. As critical dimensions decrease, and the number of materials increases, the interactions between heterogeneous materials themselves and processing increase in complexity. Traditionally, applications of ab initio techniques are confined to electronic structure and band gap calculations of bulk materials, which are then used in coarse-grained models such as mesoscopic and continuum models. Density functional theory is the most widely used ab initio technique that was successfully extended to several applications. This paper illustrates applications of density functional theory to semiconductor processes and proposes further opportunities for use of such techniques in process development.

  2. Estimation Of Demand System In An Aids Model:The Opportunity For Exporting Thai Agricultural Products

    Directory of Open Access Journals (Sweden)

    Waripas Jiumpanyarach

    2012-06-01

    Full Text Available This paper reports the results of the estimation of Almost Ideal Demand System(AIDS model is developed to estimate quantity respond based on price. Five major export agricultural products data from the office of Agricultural Economics, Thailand and Biofuel policy from the office of the National Economic and Social Development Broad were used. The AIDS model estimatesdemand of palm, cassava, and sugar are highly response to changed price. Rubber and rice has less response to the changed price. All of major agricultural products are affect expenditure of Thailand export. This result suggest that the opportunity for increasing supply of energy plants, which benefits to Thai farmer communities for expanding market share in energy plants in domestic and global market.

  3. A unified view of generative models for networks: models, methods, opportunities, and challenges

    CERN Document Server

    Jacobs, Abigail Z

    2014-01-01

    Research on probabilistic models of networks now spans a wide variety of fields, including physics, sociology, biology, statistics, and machine learning. These efforts have produced a diverse ecology of models and methods. Despite this diversity, many of these models share a common underlying structure: pairwise interactions (edges) are generated with probability conditional on latent vertex attributes. Differences between models generally stem from different philosophical choices about how to learn from data or different empirically-motivated goals. The highly interdisciplinary nature of work on these generative models, however, has inhibited the development of a unified view of their similarities and differences. For instance, novel theoretical models and optimization techniques developed in machine learning are largely unknown within the social and biological sciences, which have instead emphasized model interpretability. Here, we describe a unified view of generative models for networks that draws togethe...

  4. A Cross-Cultural Multi-agent Model of Opportunism in Trade

    Science.gov (United States)

    Hofstede, Gert Jan; Jonker, Catholijn M.; Verwaart, Tim

    According to transaction cost economics, contracts are always incomplete and offer opportunities to defect. Some level of trust is a sine qua non for trade. If the seller is better informed about product quality than the buyer, the buyer has to rely on information the seller provides or has to check the information by testing the product or tracing the supply chain processes, thus incurring extra transaction cost. An opportunistic seller who assumes the buyer to trust, may deliver a lower quality product than agreed upon. In human decisions to deceive and to show trust or distrust, issues like mutual expectations, shame, self-esteem, personality, and reputation are involved. These factors depend in part on traders' cultural background. This paper proposes an agent model of deceit and trust and describes a multi-agent simulation where trading agents are differentiated according to Hofstede's dimensions of national culture. Simulations of USA and Dutch trading situations are compared.

  5. Toward an Integrative Understanding of Social Behavior: New Models and New Opportunities

    Science.gov (United States)

    Blumstein, Daniel T.; Ebensperger, Luis A.; Hayes, Loren D.; Vásquez, Rodrigo A.; Ahern, Todd H.; Burger, Joseph Robert; Dolezal, Adam G.; Dosmann, Andy; González-Mariscal, Gabriela; Harris, Breanna N.; Herrera, Emilio A.; Lacey, Eileen A.; Mateo, Jill; McGraw, Lisa A.; Olazábal, Daniel; Ramenofsky, Marilyn; Rubenstein, Dustin R.; Sakhai, Samuel A.; Saltzman, Wendy; Sainz-Borgo, Cristina; Soto-Gamboa, Mauricio; Stewart, Monica L.; Wey, Tina W.; Wingfield, John C.; Young, Larry J.

    2010-01-01

    Social interactions among conspecifics are a fundamental and adaptively significant component of the biology of numerous species. Such interactions give rise to group living as well as many of the complex forms of cooperation and conflict that occur within animal groups. Although previous conceptual models have focused on the ecological causes and fitness consequences of variation in social interactions, recent developments in endocrinology, neuroscience, and molecular genetics offer exciting opportunities to develop more integrated research programs that will facilitate new insights into the physiological causes and consequences of social variation. Here, we propose an integrative framework of social behavior that emphasizes relationships between ultimate-level function and proximate-level mechanism, thereby providing a foundation for exploring the full diversity of factors that underlie variation in social interactions, and ultimately sociality. In addition to identifying new model systems for the study of human psychopathologies, this framework provides a mechanistic basis for predicting how social behavior will change in response to environmental variation. We argue that the study of non-model organisms is essential for implementing this integrative model of social behavior because such species can be studied simultaneously in the lab and field, thereby allowing integration of rigorously controlled experimental manipulations with detailed observations of the ecological contexts in which interactions among conspecifics occur. PMID:20661457

  6. Towards an integrative understanding of social behavior: new models and new opportunities

    Directory of Open Access Journals (Sweden)

    Daniel T Blumstein

    2010-06-01

    Full Text Available Social interactions among conspecifics are a fundamental and adaptively significant component of the biology of numerous species. Such interactions give rise to group living as well as many of the complex forms of cooperation and conflict that occur within animal groups. Although previous conceptual models have focused on the ecological causes and fitness consequences of variation in social interactions, recent developments in endocrinology, neuroscience, and molecular genetics offer exciting opportunities to develop more integrated research programs that will facilitate new insights into the physiological causes and consequences of social variation. Here, we propose an integrative framework of social behavior that emphasizes relationships between ultimate-level function and proximate-level mechanism, thereby providing a foundation for exploring the full diversity of factors that underlie variation in social interactions, and ultimately sociality. In addition to identifying new model systems for the study of human psychopathologies, this framework provides a mechanistic basis for predicting how social behavior will change in response to environmental variation. We argue that the study of non-model organisms is essential for implementing this integrative model of social behavior because such species can be studied simultaneously in the lab and field, thereby allowing integration of rigorously controlled experimental manipulations with detailed observations of the ecological contexts in which interactions among conspecifics occur.

  7. Field, experimental and numerical model developments in outburst flood understanding and opportunities for future work

    Science.gov (United States)

    Carrivick, Jonathan

    2015-04-01

    Local-scale risks to society from a rapidly changing cryosphere include a range of mass flows and floods. Most of these slides, slumps, falls and flow events have been attributed to climatically-induced permafrost degradation, to glaciological mass loss and consequent meltwater production and sudden drainage of glacier lakes, or to volcano-ice interactions. This presentation will firstly overview outburst flood research and knowledge to date and it will do this from a field, experimental and numerical modeling perspective. Fieldwork examples from around the world and including Iceland, New Zealand, Greenland, and the European Alps will be argued to underpin all understanding but to be severely limited in spatiotemporal coverage. Laboratory experiments will be argued to be overly generalised and narrowly-focussed. Numerical models will be argued to be omitting or over-generalising major processes; particularly sediment transport and morphodynamics. This presentation will then look forwards, by placing an emphasis on several recent and major technological advances that should be enabling much improved monitoring and measurement in both the field and the laboratory. The opportunity for new numerical modelling approaches will be discussed from two viewpoints; that of the researcher interested in process mechanisms, and that of the natural hazard manager wishing for real-time information.

  8. Model Meets Data: Challenges and Opportunities to Implement Land Management in Earth System Models

    Science.gov (United States)

    Pongratz, J.; Dolman, A. J.; Don, A.; Erb, K. H.; Fuchs, R.; Herold, M.; Jones, C.; Luyssaert, S.; Kuemmerle, T.; Meyfroidt, P.

    2016-12-01

    Land-based demand for food and fibre is projected to increase in the future. In light of global sustainability challenges only part of this increase will be met by expansion of land use into relatively untouched regions. Additional demand will have to be fulfilled by intensification and other adjustments in management of land that already is under agricultural and forestry use. Such land management today occurs on about half of the ice-free land surface, as compared to only about one quarter that has undergone a change in land cover. As the number of studies revealing substantial biogeophysical and biogeochemical effects of land management is increasing, moving beyond land cover change towards including land management has become a key focus for Earth system modeling. However, a basis for prioritizing land management activities for implementation in models is lacking. We lay this basis for prioritization in a collaborative project across the disciplines of Earth system modeling, land system science, and Earth observation. We first assess the status and plans of implementing land management in Earth system and dynamic global vegetation models. A clear trend towards higher complexity of land use representation is visible. We then assess five criteria for prioritizing the implementation of land management activities: (1) spatial extent, (2) evidence for substantial effects on the Earth system, (3) process understanding, (4) possibility to link the management activity to existing concepts and structures of models, (5) availability of data required as model input. While the first three criteria have been assessed by an earlier study for ten common management activities, we review strategies for implementation in models and the availability of required datasets. We can thus evaluate the management activities for their performance in terms of importance for the Earth system, possibility of technical implementation in models, and data availability. This synthesis reveals

  9. Model meets data: Challenges and opportunities to implement land management in Earth System Models

    Science.gov (United States)

    Pongratz, Julia; Dolman, Han; Don, Axel; Erb, Karl-Heinz; Fuchs, Richard; Herold, Martin; Jones, Chris; Luyssaert, Sebastiaan; Kuemmerle, Tobias; Meyfroidt, Patrick; Naudts, Kim

    2017-04-01

    Land-based demand for food and fibre is projected to increase in the future. In light of global sustainability challenges only part of this increase will be met by expansion of land use into relatively untouched regions. Additional demand will have to be fulfilled by intensification and other adjustments in management of land that already is under agricultural and forestry use. Such land management today occurs on about half of the ice-free land surface, as compared to only about one quarter that has undergone a change in land cover. As the number of studies revealing substantial biogeophysical and biogeochemical effects of land management is increasing, moving beyond land cover change towards including land management has become a key focus for Earth system modeling. However, a basis for prioritizing land management activities for implementation in models is lacking. We lay this basis for prioritization in a collaborative project across the disciplines of Earth system modeling, land system science, and Earth observation. We first assess the status and plans of implementing land management in Earth system and dynamic global vegetation models. A clear trend towards higher complexity of land use representation is visible. We then assess five criteria for prioritizing the implementation of land management activities: (1) spatial extent, (2) evidence for substantial effects on the Earth system, (3) process understanding, (4) possibility to link the management activity to existing concepts and structures of models, (5) availability of data required as model input. While the first three criteria have been assessed by an earlier study for ten common management activities, we review strategies for implementation in models and the availability of required datasets. We can thus evaluate the management activities for their performance in terms of importance for the Earth system, possibility of technical implementation in models, and data availability. This synthesis reveals

  10. Business Models in the Smart Grid: Challenges, Opportunities and Proposals for Prosumer Profitability

    Directory of Open Access Journals (Sweden)

    Jesús Rodríguez-Molina

    2014-09-01

    Full Text Available Considering that non-renewable energy resources are dwindling, the smart grid turns out to be one of the most promising and compelling systems for the future of energy. Not only does it combine efficient energy consumption with avant-garde technologies related to renewable energies, but it is also capable of providing several beneficial utilities, such as power monitoring and data provision. When smart grid end users turn into prosumers, they become arguably the most important value creators within the smart grid and a decisive agent of change in terms of electricity usage. There is a plethora of research and development areas related to the smart grid that can be exploited for new business opportunities, thus spawning another branch of the so-called “green economy” focused on turning smart energy usage into a profitable business. This paper deals with emerging business models for smart grid prosumers, their strengths and weaknesses and puts forward new prosumer-oriented business models, along with their value propositions.

  11. Addressing diverse learner preferences and intelligences with emerging technologies: Matching models to online opportunities

    Directory of Open Access Journals (Sweden)

    Ke Zhang

    2009-03-01

    Full Text Available This paper critically reviews various learning preferences and human intelligence theories and models with a particular focus on the implications for online learning. It highlights a few key models, Gardner’s multiple intelligences, Fleming and Mills’ VARK model, Honey and Mumford’s Learning Styles, and Kolb’s Experiential Learning Model, and attempts to link them to trends and opportunities in online learning with emerging technologies. By intersecting such models with online technologies, it offers instructors and instructional designers across educational sectors and situations new ways to think about addressing diverse learner needs, backgrounds, and expectations. Learning technologies are important for effective teaching, as are theories and models and theories of learning. We argue that more immense power can be derived from connections between the theories, models and learning technologies. Résumé : Cet article passe en revue de manière critique les divers modèles et théories sur les préférences d’apprentissage et l’intelligence humaine, avec un accent particulier sur les implications qui en découlent pour l’apprentissage en ligne. L’article présente quelques-uns des principaux modèles (les intelligences multiples de Gardner, le modèle VAK de Fleming et Mills, les styles d’apprentissage de Honey et Mumford et le modèle d’apprentissage expérientiel de Kolb et tente de les relier à des tendances et occasions d’apprentissage en ligne qui utilisent les nouvelles technologies. En croisant ces modèles avec les technologies Web, les instructeurs et concepteurs pédagogiques dans les secteurs de l’éducation ou en situation éducationnelle se voient offrir de nouvelles façons de tenir compte des divers besoins, horizons et attentes des apprenants. Les technologies d’apprentissage sont importantes pour un enseignement efficace, tout comme les théories et les modèles d’apprentissage. Nous sommes d

  12. Methodological challenges and analytic opportunities for modeling and interpreting Big Healthcare Data.

    Science.gov (United States)

    Dinov, Ivo D

    2016-01-01

    Managing, processing and understanding big healthcare data is challenging, costly and demanding. Without a robust fundamental theory for representation, analysis and inference, a roadmap for uniform handling and analyzing of such complex data remains elusive. In this article, we outline various big data challenges, opportunities, modeling methods and software techniques for blending complex healthcare data, advanced analytic tools, and distributed scientific computing. Using imaging, genetic and healthcare data we provide examples of processing heterogeneous datasets using distributed cloud services, automated and semi-automated classification techniques, and open-science protocols. Despite substantial advances, new innovative technologies need to be developed that enhance, scale and optimize the management and processing of large, complex and heterogeneous data. Stakeholder investments in data acquisition, research and development, computational infrastructure and education will be critical to realize the huge potential of big data, to reap the expected information benefits and to build lasting knowledge assets. Multi-faceted proprietary, open-source, and community developments will be essential to enable broad, reliable, sustainable and efficient data-driven discovery and analytics. Big data will affect every sector of the economy and their hallmark will be 'team science'.

  13. Can an Opportunity to Learn at Work Reduce Stress?: A Revisitation of the Job Demand-Control Model

    Science.gov (United States)

    Panari, Chiara; Guglielmi, Dina; Simbula, Silvia; Depolo, Marco

    2010-01-01

    Purpose: This paper aims to extend the stress-buffering hypothesis of the demand-control model. In addition to the control variable, it seeks to analyse the role of an opportunity for learning and development (L&D) in the workplace as a moderator variable between increased demands and need for recovery. Design/methodology/approach: A…

  14. Revisiting the destination ranking procedure in development of an Intervening Opportunities Model for public transit trip distribution

    Science.gov (United States)

    Nazem, Mohsen; Trépanier, Martin; Morency, Catherine

    2015-01-01

    An Enhanced Intervening Opportunities Model (EIOM) is developed for Public Transit (PT). This is a distribution supply dependent model, with single constraints on trip production for work trips during morning peak hours (6:00 a.m.-9:00 a.m.) within the Island of Montreal, Canada. Different data sets, including the 2008 Origin-Destination (OD) survey of the Greater Montreal Area, the 2006 Census of Canada, GTFS network data, along with the geographical data of the study area, are used. EIOM is a nonlinear model composed of socio-demographics, PT supply data and work location attributes. An enhanced destination ranking procedure is used to calculate the number of spatially cumulative opportunities, the basic variable of EIOM. For comparison, a Basic Intervening Opportunities Model (BIOM) is developed by using the basic destination ranking procedure. The main difference between EIOM and BIOM is in the destination ranking procedure: EIOM considers the maximization of a utility function composed of PT Level Of Service and number of opportunities at the destination, along with the OD trip duration, whereas BIOM is based on a destination ranking derived only from OD trip durations. Analysis confirmed that EIOM is more accurate than BIOM. This study presents a new tool for PT analysts, planners and policy makers to study the potential changes in PT trip patterns due to changes in socio-demographic characteristics, PT supply, and other factors. Also it opens new opportunities for the development of more accurate PT demand models with new emergent data such as smart card validations.

  15. Opportunity Design

    DEFF Research Database (Denmark)

    2012-01-01

    or development oriented, the act of ‘recognition’ is still a central part of the definition. Recently the term “Opportunity Design” has been introduced, suggesting that opportunities can be proactively and intentionally designed. However, the relatedness between the opportunity recognition process...... and opportunity design is not clear. Furthermore, there is still a lack of approaches, methods and tools, which can support entrepreneurs in designing the entrepreneurial opportunities. In this paper, we take steps towards defining opportunity design in respect to the opportunity recognition process, and identify...... some of the specific approaches applicable to the design of opportunities. By looking at industrial designers working with entrepreneurial opportunities, it becomes evident that there is a set of approaches, which can turn the opportunity recognition process into an intentional and proactive process....

  16. Opportunity Design

    DEFF Research Database (Denmark)

    2012-01-01

    some of the specific approaches applicable to the design of opportunities. By looking at industrial designers working with entrepreneurial opportunities, it becomes evident that there is a set of approaches, which can turn the opportunity recognition process into an intentional and proactive process....... or development oriented, the act of ‘recognition’ is still a central part of the definition. Recently the term “Opportunity Design” has been introduced, suggesting that opportunities can be proactively and intentionally designed. However, the relatedness between the opportunity recognition process...... and opportunity design is not clear. Furthermore, there is still a lack of approaches, methods and tools, which can support entrepreneurs in designing the entrepreneurial opportunities. In this paper, we take steps towards defining opportunity design in respect to the opportunity recognition process, and identify...

  17. Opportunities for Using Building Information Modeling to Improve Worker Safety Performance

    Directory of Open Access Journals (Sweden)

    Kasim Alomari

    2017-02-01

    Full Text Available Building information modelling (BIM enables the creation of a digital representation of a designed facility combined with additional information about the project attributes, performance criteria, and construction process. Users of BIM tools point to the ability to visualize the final design along with the construction process as a beneficial feature of using BIM. Knowing the construction process in relationship to a facility’s design benefits both safety professionals when planning worker safety measures for a project and designers when creating a project’s design. Success in using BIM to enhance safety partly depends on the familiarity of project personnel with BIM tools and the extent to which the tools can be used to identify and eliminate safety hazards. In a separate, ongoing study, the authors investigated the connection between BIM and safety to document the opportunities, barriers, and impacts. Utilizing an on-line survey of project engineers who work for construction firms together with a comprehensive literature review, the study found those who use BIM feel that it aids in communication of project information and project delivery, both of which have been found to have positive impacts on construction site safety. Further, utilizing the survey results, the authors apply the binary logistic regression econometric framework to better understand the factors that lead to safety professionals believing that BIM increases safety in the work place. In addition, according to the survey results, a large percentage of the engineers who use BIM feel that ultimately it helps to eliminate safety hazards and improve worker safety. The study findings suggest that improvements in safety performance across the construction industry may be due in part to increased use of BIM in the construction industry.

  18. Modeling Distribution and Abundance of Antarctic Baleen Whales Using Ships of Opportunity

    Directory of Open Access Journals (Sweden)

    Rob Williams

    2006-06-01

    Full Text Available Information on animal abundance and distribution is at the cornerstone of many wildlife and conservation strategies. However, these data can be difficult and costly to obtain for cetacean species. The expense of sufficient ship time to conduct design-unbiased line transect surveys may be simply out of reach for researchers in many countries, which nonetheless grapple with problems of conservation of endangered species, by-catch of small cetaceans in commercial fisheries, and progression toward ecosystem-based fisheries management. Recently developed spatial modeling techniques show promise for estimating wildlife abundance using non-randomized surveys, but have yet to receive much field-testing in areas where designed surveys have also been conducted. Effort and sightings data were collected along 9 650 km of transects aboard ships of opportunity in the Southern Ocean during the austral summers of 2000-2001 and 2001-2002. Generalized additive models with generalized cross-validation were used to express heterogeneity of cetacean sightings as functions of spatial covariates. Models were used to map predicted densities and to estimate abundance of humpback, minke, and fin whales in the Drake Passage and along the Antarctic Peninsula. All species' distribution maps showed strong density gradients, which were robust to jackknife resampling when each of 14 trips was removed sequentially with replacement. Looped animations of model predictions of whale density illustrate uncertainty in distribution estimates in a way that is informative to non-scientists. The best abundance estimate for humpback whales was 1 829 (95% CI: 978-3 422. Abundance of fin whales was 4 487 (95% CI: 1 326-15 179 and minke whales was 1,544 (95% CI: 1,221-1,953. These estimates agreed roughly with those reported from a designed survey conducted in the region during the previous austral summer. These estimates assumed that all animals on the trackline were detected, but

  19. A Model Lesson: Finland Shows Us What Equal Opportunity Looks Like

    Science.gov (United States)

    Sahlberg, Pasi

    2012-01-01

    International indicators show that Finland has one of the most educated citizenries in the world, provides educational opportunities in an egalitarian manner, and makes efficient use of resources. But at the beginning of the 1990s, education in Finland was nothing special in international terms. The performance of Finnish students on international…

  20. Classroom ICT Integration in Tanzania: Opportunities and Challenges from the Perspectives of TPACK and SAMR Models

    Science.gov (United States)

    Kihoza, Patrick; Zlotnikova, Irina; Bada, Joseph; Kalegele, Khamisi

    2016-01-01

    With the education systems demand of contemporary technologies, teacher trainees should be imparted with competencies and skills to integrate information and communication technology (ICT) into their future teaching and learning practices. This study assessed classroom ICTs integration opportunities and the challenges in relation to Technological…

  1. The guiding nature of the kawa (river) model in Ireland: creating both opportunities and challenges for occupational therapists.

    Science.gov (United States)

    Carmody, Sarah; Nolan, Riona; Ni Chonchuir, Niamhh; Curry, Maria; Halligan, Catherine; Robinson, Katie

    2007-01-01

    The kawa (kawa is Japanese for 'river') model of occupational therapy has recently emerged in response to the needs for culturally sensitive conceptual models of practice that adequately address clients' diverse cultures and belief systems (Iwama, 2006a). The present article reports two case studies in which the kawa model was used to guide occupational therapy intervention with two individuals with multiple sclerosis in Ireland, with the aim of exploring the effectiveness of the recently emerged kawa model. A qualitative grounded theory approach using case-study methodology was undertaken. Semi-structured interviews based on the kawa model were completed with two participants with multiple sclerosis before and after occupational therapy intervention. The authors also documented their experience of using the model in reflective diaries. Analysis revealed a core category of the guiding nature of the kawa model creating both opportunities and challenges. Opportunities afforded by the model included enablement of the occupational therapy process and facilitation of occupation-based practice. Challenges created by the use of the kawa model included participant uncertainty and the influence of therapist preconceptions. Limitations and recommendations for future research are discussed in terms of generalizability. Further research with greater numbers and more diversity of study participants is required to validate the tentative theory proposed.

  2. Opportunities for Cross-Border Entrepreneurship Development in a Cluster Model Exemplified by the Polish–Czech Border Region

    OpenAIRE

    Joanna Kurowska-Pysz

    2016-01-01

    The subject of the paper is the analysis and evaluation of cross-border entrepreneurship development opportunities on the basis of cross-border cooperation, which has gradually evolved from consisting of bilateral partnerships to a networking model or even a cluster. The study conducted at the Polish–Czech border area indicates that, in terms of the development of cross-border cooperation, the economic sphere is lagging far behind social activities such as culture, education and tourism. At t...

  3. Corrosion chemistry closing comments: opportunities in corrosion science facilitated by operando experimental characterization combined with multi-scale computational modelling.

    Science.gov (United States)

    Scully, John R

    2015-01-01

    Recent advances in characterization tools, computational capabilities, and theories have created opportunities for advancement in understanding of solid-fluid interfaces at the nanoscale in corroding metallic systems. The Faraday Discussion on Corrosion Chemistry in 2015 highlighted some of the current needs, gaps and opportunities in corrosion science. Themes were organized into several hierarchical categories that provide an organizational framework for corrosion. Opportunities to develop fundamental physical and chemical data which will enable further progress in thermodynamic and kinetic modelling of corrosion were discussed. These will enable new and better understanding of unit processes that govern corrosion at the nanoscale. Additional topics discussed included scales, films and oxides, fluid-surface and molecular-surface interactions, selected topics in corrosion science and engineering as well as corrosion control. Corrosion science and engineering topics included complex alloy dissolution, local corrosion, and modelling of specific corrosion processes that are made up of collections of temporally and spatially varying unit processes such as oxidation, ion transport, and competitive adsorption. Corrosion control and mitigation topics covered some new insights on coatings and inhibitors. Further advances in operando or in situ experimental characterization strategies at the nanoscale combined with computational modelling will enhance progress in the field, especially if coupling across length and time scales can be achieved incorporating the various phenomena encountered in corrosion. Readers are encouraged to not only to use this ad hoc organizational scheme to guide their immersion into the current opportunities in corrosion chemistry, but also to find value in the information presented in their own ways.

  4. Model-based drug development: strengths, weaknesses, opportunities, and threats for broad application of pharmacometrics in drug development.

    Science.gov (United States)

    Wetherington, Jeffrey D; Pfister, Marc; Banfield, Christopher; Stone, Julie A; Krishna, Rajesh; Allerheiligen, Sandy; Grasela, Dennis M

    2010-09-01

    Systematic implementation of model-based drug development (MBDD) to drug discovery and development has the potential to significantly increase the rate of medical breakthroughs and make available new and better treatments to patients. An analysis of the strengths, weaknesses, opportunities, and threats (ie, SWOT) was conducted through focus group discussions that included 24 members representing 8 pharmaceutical companies to systematically assess the challenges to implementing MBDD into the drug development decision-making process. The application of the SWOT analysis to the successful implementation of MBDD yielded 19 strengths, 27 weaknesses, 34 opportunities, and 22 threats, which support the following conclusions. The shift from empirical drug development to MBDD requires a question-based mentality; early, proactive planning; dynamic access to multisource data; quantitative knowledge integration; multidisciplinary collaboration; effective communication and leadership skills; and innovative, impactful application of pharmacometrics focused on enhancing quantitative decision making. The ultimate goal of MBDD is to streamline discovery and development of innovative medicines to benefit patients.

  5. Opportunity Design

    DEFF Research Database (Denmark)

    Løwe Nielsen, Suna; Lassen, Astrid Heidemann; Nielsen, Louise Møller

    2013-01-01

    in a market setting (the back-end of entrepreneurial processes), it pays less attention to how entrepreneurs purposely design opportunities (the front-end of entrepreneurial processes). Drawing on methods and processes from the creative design literature, the paper introduces a framework of “opportunity...

  6. Opportunity Design

    DEFF Research Database (Denmark)

    Løwe Nielsen, Suna; Lassen, Astrid Heidemann; Nielsen, Louise Møller

    2013-01-01

    design”. The framework explains how opportunities intentionally and pro-actively can be designed from methods and processes of moving-in and moving-out. An illustrative case of opportunity design within the area of sustainable energy and electric cars is presented to link the theoretical discussion...

  7. Development of a Coherent Bistatic Vegetation Model for Signal of Opportunity Applications at VHF UHF-Bands

    Science.gov (United States)

    Kurum, Mehmet; Deshpande, Manohar; Joseph, Alicia T.; O'Neill, Peggy E.; Lang, Roger H.; Eroglu, Orhan

    2017-01-01

    A coherent bistatic vegetation scattering model, based on a Monte Carlo simulation, is being developed to simulate polarimetric bi-static reflectometry at VHF/UHF-bands (240-270 MHz). The model is aimed to assess the value of geostationary satellite signals of opportunity to enable estimation of the Earth's biomass and root-zone soil moisture. An expression for bistatic scattering from a vegetation canopy is derived for the practical case of a ground-based/low altitude platforms with passive receivers overlooking vegetation. Using analytical wave theory in conjunction with distorted Born approximation (DBA), the transmit and receive antennas effects (i.e., polarization, orientation, height, etc.) are explicitly accounted for. Both the coherency nature of the model (joint phase and amplitude information) and the explicit account of system parameters (antenna, altitude, polarization, etc) enable one to perform various beamforming techniques to evaluate realistic deployment configurations. In this paper, several test scenarios will be presented and the results will be evaluated for feasibility for future biomass and root-zone soil moisture application using geostationary communication satellite signals of opportunity at low frequencies.

  8. Evapotranspiration and irrigation algorithms in hydrologic modeling:Present Status and Opportunities

    Science.gov (United States)

    Hydrologic models are used extensively for predicting water availability and water quality responses to alternative irrigation, tillage, crop, and fertilizer management practices and global climate change. Modeling results have been frequently used by regulatory agencies for developing remedial meas...

  9. Towards a predictive systems-level model of the human microbiome: progress, challenges, and opportunities.

    Science.gov (United States)

    Greenblum, Sharon; Chiu, Hsuan-Chao; Levy, Roie; Carr, Rogan; Borenstein, Elhanan

    2013-08-01

    The human microbiome represents a vastly complex ecosystem that is tightly linked to our development, physiology, and health. Our increased capacity to generate multiple channels of omic data from this system, brought about by recent advances in high throughput molecular technologies, calls for the development of systems-level methods and models that take into account not only the composition of genes and species in a microbiome but also the interactions between these components. Such models should aim to study the microbiome as a community of species whose metabolisms are tightly intertwined with each other and with that of the host, and should be developed with a view towards an integrated, comprehensive, and predictive modeling framework. Here, we review recent work specifically in metabolic modeling of the human microbiome, highlighting both novel methodologies and pressing challenges. We discuss various modeling approaches that lay the foundation for a full-scale predictive model, focusing on models of interactions between microbial species, metagenome-scale models of community-level metabolism, and models of the interaction between the microbiome and the host. Continued development of such models and of their integration into a multi-scale model of the microbiome will lead to a deeper mechanistic understanding of how variation in the microbiome impacts the host, and will promote the discovery of clinically relevant and ecologically relevant insights from the rich trove of data now available. Copyright © 2013 Elsevier Ltd. All rights reserved.

  10. Opportunities for Cross-Border Entrepreneurship Development in a Cluster Model Exemplified by the Polish–Czech Border Region

    Directory of Open Access Journals (Sweden)

    Joanna Kurowska-Pysz

    2016-03-01

    Full Text Available The subject of the paper is the analysis and evaluation of cross-border entrepreneurship development opportunities on the basis of cross-border cooperation, which has gradually evolved from consisting of bilateral partnerships to a networking model or even a cluster. The study conducted at the Polish–Czech border area indicates that, in terms of the development of cross-border cooperation, the economic sphere is lagging far behind social activities such as culture, education and tourism. At the same time, Polish and Czech enterprises are not sufficiently mobilized to develop cross-border entrepreneurship, although a number of support instruments in this regard have been proposed. Sustainable development of the border should take into account both social and economic aspects. An important research problem therefore becomes determining the possibility of boosting the development of cross-border entrepreneurship on the basis of the existing forms of cross-border cooperation, including cooperation in the social sphere. The aim of this paper is to define the conditions and opportunities for the development of cluster cooperation in the area of cross-border entrepreneurship. The author has attempted to resolve whether the intensity of cross-border cooperation can be a factor which mobilizes companies to develop their cross-border entrepreneurship and whether cross-border entrepreneurship can be further developed within the cluster model.

  11. Modelling the social and structural determinants of tuberculosis: opportunities and challenges.

    Science.gov (United States)

    Pedrazzoli, D; Boccia, D; Dodd, P J; Lönnroth, K; Dowdy, D W; Siroka, A; Kimerling, M E; White, R G; Houben, R M G J

    2017-09-01

    Despite the close link between tuberculosis (TB) and poverty, most mathematical models of TB have not addressed underlying social and structural determinants. To review studies employing mathematical modelling to evaluate the epidemiological impact of the structural determinants of TB. We systematically searched PubMed and personal libraries to identify eligible articles. We extracted data on the modelling techniques employed, research question, types of structural determinants modelled and setting. From 232 records identified, we included eight articles published between 2008 and 2015; six employed population-based dynamic TB transmission models and two non-dynamic analytic models. Seven studies focused on proximal TB determinants (four on nutritional status, one on wealth, one on indoor air pollution, and one examined overcrowding, socio-economic and nutritional status), and one focused on macro-economic influences. Few modelling studies have attempted to evaluate structural determinants of TB, resulting in key knowledge gaps. Despite the challenges of modelling such a complex system, models must broaden their scope to remain useful for policy making. Given the intersectoral nature of the interrelations between structural determinants and TB outcomes, this work will require multidisciplinary collaborations. A useful starting point would be to focus on developing relatively simple models that can strengthen our knowledge regarding the potential effect of the structural determinants on TB outcomes.

  12. Opportunities for computer abuse

    DEFF Research Database (Denmark)

    Willison, Robert Andrew; Backhouse, James

    2005-01-01

    Systems risk refers to the likelihood that an IS is inadequately guarded against certain types of damage or loss. While risks are posed by acts of God, hackers and viruses, consideration should also be given to the `insider' threat of dishonest employees, intent on undertaking some form of computer...... for the offender. To achieve this goal a model known as the `Crime Specific Opportunity Structure' is advanced. Focussing on the opportunities for computer abuse, the model addresses the nature of such opportunities with regards to the organisational context and the threats posed by rogue employees. Drawing...

  13. Opportunities for computer abuse

    DEFF Research Database (Denmark)

    Willison, Robert Andrew; Backhouse, James

    2005-01-01

    Systems risk refers to the likelihood that an IS is inadequately guarded against certain types of damage or loss. While risks are posed by acts of God, hackers and viruses, consideration should also be given to the `insider' threat of dishonest employees, intent on undertaking some form of computer...... for the offender. To achieve this goal a model known as the `Crime Specific Opportunity Structure' is advanced. Focussing on the opportunities for computer abuse, the model addresses the nature of such opportunities with regards to the organisational context and the threats posed by rogue employees. Drawing...

  14. Tools and Products of Real-Time Modeling: Opportunities for Space Weather Forecasting

    Science.gov (United States)

    Hesse, Michael

    2009-01-01

    The Community Coordinated Modeling Center (CCMC) is a US inter-agency activity aiming at research in support of the generation of advanced space weather models. As one of its main functions, the CCMC provides to researchers the use of space science models, even if they are not model owners themselves. The second CCMC activity is to support Space Weather forecasting at national Space Weather Forecasting Centers. This second activity involves model evaluations, model transitions to operations, and the development of draft Space Weather forecasting tools. This presentation will focus on the last element. Specifically, we will discuss present capabilities, and the potential to derive further tools. These capabilities will be interpreted in the context of a broad-based, bootstrapping activity for modern Space Weather forecasting.

  15. Research report on new business opportunities and models in Finnish biorefining industry; Biotuli. Selvitys bioliiketoiminnan uusista liiketoimintamahdollisuuksista ja -malleista

    Energy Technology Data Exchange (ETDEWEB)

    Hono, E.

    2013-11-01

    This report is a part of BIOTULI-project, which focuses on new products and business models for Finnish biorefining industry. The objective of this report is to review the business models required to capture value from the business opportunities discovered in BIOTULI-project. Report also aims to define the supply chain required for the business model and prerequisites for conducting profitable business in small and medium-scale enterprises. The report consists of two cases. Combining torrefaction with small-scale heat production and producing a biodegradable disinfectant with a new separation technique developed in BIOTULI-project. Research was conducted by literature review and interviews with experts from related fields. A business model was done for both cases. The execution and future developments of both business models were assessed. According to the analysis done for this report, combining torrefaction with a small-scale heat production is not profitable at moment. Possible changes in markets might make this business concept more lucrative in the future. The new biodegradable disinfectant has a significant commercial potential, but the research is still unfinished and it's too early to make an accurate evaluation of the business models profitability. Results of this paper can be used as a base for more comprehensive research projects regarding these business models. (orig.)

  16. Opportunities and challenges in supply-side simulation: physician-based models.

    Science.gov (United States)

    Gresenz, Carole Roan; Auerbach, David I; Duarte, Fabian

    2013-04-01

    To provide a conceptual framework and to assess the availability of empirical data for supply-side microsimulation modeling in the context of health care. Multiple secondary data sources, including the American Community Survey, Health Tracking Physician Survey, and SK&A physician database. We apply our conceptual framework to one entity in the health care market-physicians-and identify, assess, and compare data available for physician-based simulation models. Our conceptual framework describes three broad types of data required for supply-side microsimulation modeling. Our assessment of available data for modeling physician behavior suggests broad comparability across various sources on several dimensions and highlights the need for significant integration of data across multiple sources to provide a platform adequate for modeling. A growing literature provides potential estimates for use as behavioral parameters that could serve as the models' engines. Sources of data for simulation modeling that account for the complex organizational and financial relationships among physicians and other supply-side entities are limited. A key challenge for supply-side microsimulation modeling is optimally combining available data to harness their collective power. Several possibilities also exist for novel data collection. These have the potential to serve as catalysts for the next generation of supply-side-focused simulation models to inform health policy. © Health Research and Educational Trust.

  17. Opportunities and Challenges in Supply-Side Simulation: Physician-Based Models

    Science.gov (United States)

    Gresenz, Carole Roan; Auerbach, David I; Duarte, Fabian

    2013-01-01

    Objective To provide a conceptual framework and to assess the availability of empirical data for supply-side microsimulation modeling in the context of health care. Data Sources Multiple secondary data sources, including the American Community Survey, Health Tracking Physician Survey, and SK&A physician database. Study Design We apply our conceptual framework to one entity in the health care market—physicians—and identify, assess, and compare data available for physician-based simulation models. Principal Findings Our conceptual framework describes three broad types of data required for supply-side microsimulation modeling. Our assessment of available data for modeling physician behavior suggests broad comparability across various sources on several dimensions and highlights the need for significant integration of data across multiple sources to provide a platform adequate for modeling. A growing literature provides potential estimates for use as behavioral parameters that could serve as the models' engines. Sources of data for simulation modeling that account for the complex organizational and financial relationships among physicians and other supply-side entities are limited. Conclusions A key challenge for supply-side microsimulation modeling is optimally combining available data to harness their collective power. Several possibilities also exist for novel data collection. These have the potential to serve as catalysts for the next generation of supply-side-focused simulation models to inform health policy. PMID:23347041

  18. Reviewing the Role of Stakeholders in Operational Research: Opportunities for Group Model Building

    NARCIS (Netherlands)

    Gooyert, V. de; Rouwette, E.A.J.A.; Kranenburg, H.L. van

    2013-01-01

    Stakeholders have always received much attention in system dynamics, especially in the group model building tradition, which emphasizes the deep involvement of a client group in building a system dynamics model. In organizations, stakeholders are gaining more and more attention by managers who try t

  19. Cowichan Valley energy mapping and modelling. Report 3 - Analysis of potentially applicable distributed energy opportunities. Final report. [Vancouver Island, Canada

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-06-15

    The driving force behind the Integrated Energy Mapping and Analysis project was the identification and analysis of a suite of pathways that the Cowichan Valley Regional District (CVRD) can utilise to increase its energy resilience, as well as reduce energy consumption and GHG emissions, with a primary focus on the residential sector. Mapping and analysis undertaken will support provincial energy and GHG reduction targets, and the suite of pathways outlined will address a CVRD internal target that calls for 75% of the region's energy within the residential sector to come from locally sourced renewables by 2050. The target has been developed as a mechanism to meet resilience and climate action target. The maps and findings produced are to be integrated as part of a regional policy framework currently under development. The third task built upon the findings of the previous two and undertook an analysis of potentially applicable distributed energy opportunities. These opportunities were analysed given a number of different parameters, which were decided upon in consultation with the CVRD. The primary output of this task was a series of cost figures for the various technologies, thus allowing comparison on a cents/kWh basis. All of the cost figures from this task have been entered into a tailor made Excel model. This 'technology cost' model is linked to the Excel scenario model utilised in task 4. As a result, as technology costs change, they can be updated accordingly and be reflected in the scenarios. Please note, that the technologies considered at present in the technology cost model are well-proven technologies, available in the market today, even though the output is being used for an analysis of development until 2050. Task 3 results are detailed in this report and both presents an initial screening for various local renewable energies, and provides the CVRD with the means of evaluating the costs and benefits of local energy productions versus

  20. Using natural selection and optimization for smarter vegetation models - challenges and opportunities

    Science.gov (United States)

    Franklin, Oskar; Han, Wang; Dieckmann, Ulf; Cramer, Wolfgang; Brännström, Åke; Pietsch, Stephan; Rovenskaya, Elena; Prentice, Iain Colin

    2017-04-01

    Dynamic global vegetation models (DGVMs) are now indispensable for understanding the biosphere and for estimating the capacity of ecosystems to provide services. The models are continuously developed to include an increasing number of processes and to utilize the growing amounts of observed data becoming available. However, while the versatility of the models is increasing as new processes and variables are added, their accuracy suffers from the accumulation of uncertainty, especially in the absence of overarching principles controlling their concerted behaviour. We have initiated a collaborative working group to address this problem based on a 'missing law' - adaptation and optimization principles rooted in natural selection. Even though this 'missing law' constrains relationships between traits, and therefore can vastly reduce the number of uncertain parameters in ecosystem models, it has rarely been applied to DGVMs. Our recent research have shown that optimization- and trait-based models of gross primary production can be both much simpler and more accurate than current models based on fixed functional types, and that observed plant carbon allocations and distributions of plant functional traits are predictable with eco-evolutionary models. While there are also many other examples of the usefulness of these and other theoretical principles, it is not always straight-forward to make them operational in predictive models. In particular on longer time scales, the representation of functional diversity and the dynamical interactions among individuals and species presents a formidable challenge. Here we will present recent ideas on the use of adaptation and optimization principles in vegetation models, including examples of promising developments, but also limitations of the principles and some key challenges.

  1. Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Afford New Opportunities in Inherited Cardiovascular Disease Modeling

    Directory of Open Access Journals (Sweden)

    Daniel R. Bayzigitov

    2016-01-01

    Full Text Available Fundamental studies of molecular and cellular mechanisms of cardiovascular disease pathogenesis are required to create more effective and safer methods of their therapy. The studies can be carried out only when model systems that fully recapitulate pathological phenotype seen in patients are used. Application of laboratory animals for cardiovascular disease modeling is limited because of physiological differences with humans. Since discovery of induced pluripotency generating induced pluripotent stem cells has become a breakthrough technology in human disease modeling. In this review, we discuss a progress that has been made in modeling inherited arrhythmias and cardiomyopathies, studying molecular mechanisms of the diseases, and searching for and testing drug compounds using patient-specific induced pluripotent stem cell-derived cardiomyocytes.

  2. Identifying Opportunities to Reduce Uncertainty in a National-Scale Forest Carbon Accounting Model

    Science.gov (United States)

    Shaw, C. H.; Metsaranta, J. M.; Kurz, W.; Hilger, A.

    2013-12-01

    Assessing the quality of forest carbon budget models used for national and international reporting of greenhouse gas emissions is essential, but model evaluations are rarely conducted mainly because of lack of appropriate, independent ground plot data sets. Ecosystem carbon stocks for all major pools estimated from data collected for 696 ground plots from Canada's new National Forest Inventory (NFI) were used to assess plot-level carbon stocks predicted by the Carbon Budget Model of the Canadian Forest Sector 3 (CBM-CFS3) -- a model compliant with the most complex (Tier-3) approach in the reporting guidelines of the Intergovernmental Panel on Climate Change. The model is the core of Canada's National Forest Carbon Monitoring, Accounting, and Reporting System. At the landscape scale, a major portion of total uncertainty in both C stock and flux estimation is associated with biomass productivity, turnover, and soil and dead organic matter modelling parameters, which can best be further evaluated using plot-level data. Because the data collected for the ground plots were comprehensive we were able to compare carbon stock estimates for 13 pools also estimated by the CBM-CFS3 (all modelled pools excepting coarse and fine root biomass) using the classical comparison statistics of mean difference and correlation. Using a Monte Carlo approach we were able to determine the contribution of aboveground biomass, deadwood and soil pool error to modeled ecosystem total error, as well as the contribution of pools that are summed to estimate aboveground biomass, deadwood and soil, to the error of these three subtotal pools. We were also able to assess potential sources of error propagation in the computational sequence of the CBM-CFS3. Analysis of the data grouped by the 16 dominant tree species allowed us to isolate the leading species where further research would lead to the greatest reductions in uncertainty for modeling of carbon stocks using the CBM-CFS3. This analysis

  3. Opportunities from low-resolution modelling of river morphology in remote parts of the world

    Science.gov (United States)

    Nones, M.; Guerrero, M.; Ronco, P.

    2014-01-01

    River morphodynamics are the result of a variety of processes, ranging from the typical small-scale of fluid mechanics (e.g. flow turbulence dissipation) to the large-scale of landscape evolution (e.g. fan deposition). However, problems inherent in the long-term modelling of large rivers derive from limited computational resources and the high level of process detail (i.e. spatial and temporal resolution). These modelling results depend on processes parameterization and calibrations based on detailed field data (e.g. initial morphology). Thus, for these cases, simplified tools are attractive. In this paper, a simplified 1-D approach is presented that is suited for modelling very large rivers. A synthetic description of the variations of cross-sections shapes is implemented on the basis of satellite images, typically also available for remote parts of the world. The model's flexibility is highlighted here by presenting two applications. In the first case, the model is used for analysing the long-term evolution of the lower Zambezi River (Africa) as it relates to the construction of two reservoirs for hydropower exploitation. In the second case, the same model is applied to study the evolution of the middle and lower Paraná River (Argentina), particularly in the context of climate variability. In both cases, having only basic data for boundary and initial conditions, the 1-D model provides results that are in agreement with past studies and therefore shows potential to be used to assist sediment management at the watershed scale or at boundaries of more detailed models.

  4. New opportunities for integrating mechanisms into soil carbon models for global simulations (Invited)

    Science.gov (United States)

    Torn, M. S.; Riley, W. J.; Contributions From: The Lake Constance Think Tank On Global Change; Feedback From Organic Carbon Dynamics-An Esf Workshop

    2010-12-01

    Numerical models of soil carbon cycling are being used to attribute carbon sinks, predict climate-ecosystem feedbacks, and evaluate climate mitigation strategies such as biofuels and sequestration. Current conceptions of SOC cycling and its expression in mathematical models rest heavily on the concept of recalcitrance - that some organic structures are intrinsically inert. However, recent research enabled by isotopic, spectroscopic, and molecular marker tools finds little evidence that recalcitrance, for example through selective preservation of plant derived material or resynthesis products, determines the long residence time of some OC in soils in a generalizable way. More likely, rates of carbon cycling are determined by the interaction of the organic matter and the soil environment including microorganisms, mineralogy, and climate. This does not mean compound chemistry is not important, rather that it does not act in isolation of other factors. Without the foundational principle that chemical composition defines the rate of decomposition, many tenets of old models are not supported, for example regarding decomposition response to change in temperature or plant species composition. Much progress could be made in the near term to improve soil carbon models by, for example, improving representations of oxygen diffusion and limitation, root carbon inputs, isotopic tracers, and making depth- or transport-related processes explicit. In other areas, new research is needed to translate recent findings into new parameters, for example, to replace texture with parameters for reactive mineral surface area to represent organo-mineral interaction. For the next generation of land model in the Community Earth System Model (was Community Climate System Model), we are developing new representations of many of these processes based on new data and understandings, to enable more accurate assessment of the vulnerability of soil organic carbon to predicted global climate change.

  5. Opportunities for improving animal welfare in rodent models of epilepsy and seizures.

    Science.gov (United States)

    Lidster, Katie; Jefferys, John G; Blümcke, Ingmar; Crunelli, Vincenzo; Flecknell, Paul; Frenguelli, Bruno G; Gray, William P; Kaminski, Rafal; Pitkänen, Asla; Ragan, Ian; Shah, Mala; Simonato, Michele; Trevelyan, Andrew; Volk, Holger; Walker, Matthew; Yates, Neil; Prescott, Mark J

    2016-02-15

    Animal models of epilepsy and seizures, mostly involving mice and rats, are used to understand the pathophysiology of the different forms of epilepsy and their comorbidities, to identify biomarkers, and to discover new antiepileptic drugs and treatments for comorbidities. Such models represent an important area for application of the 3Rs (replacement, reduction and refinement of animal use). This report provides background information and recommendations aimed at minimising pain, suffering and distress in rodent models of epilepsy and seizures in order to improve animal welfare and optimise the quality of studies in this area. The report includes practical guidance on principles of choosing a model, induction procedures, in vivo recordings, perioperative care, welfare assessment, humane endpoints, social housing, environmental enrichment, reporting of studies and data sharing. In addition, some model-specific welfare considerations are discussed, and data gaps and areas for further research are identified. The guidance is based upon a systematic review of the scientific literature, survey of the international epilepsy research community, consultation with veterinarians and animal care and welfare officers, and the expert opinion and practical experience of the members of a Working Group convened by the United Kingdom's National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs).

  6. Outcomes and opportunities: a nurse-led model of chronic disease management in Australian general practice.

    Science.gov (United States)

    Eley, Diann S; Patterson, Elizabeth; Young, Jacqui; Fahey, Paul P; Del Mar, Chris B; Hegney, Desley G; Synnott, Robyn L; Mahomed, Rosemary; Baker, Peter G; Scuffham, Paul A

    2013-01-01

    The Australian government's commitment to health service reform has placed general practice at the centre of its agenda to manage chronic disease. Concerns about the capacity of GPs to meet the growing chronic disease burden has stimulated the implementation and testing of new models of care that better utilise practice nurses (PN). This paper reports on a mixed-methods study nested within a larger study that trialled the feasibility and acceptability of a new model of nurse-led chronic disease management in three general practices. Patients over 18 years of age with type 2 diabetes, hypertension or stable ischaemic heart disease were randomised into PN-led or usual GP-led care. Primary outcomes were self-reported quality of life and perceptions of the model's feasibility and acceptability from the perspective of patients and GPs. Over the 12-month study quality of life decreased but the trend between groups was not statistically different. Qualitative data indicate that the PN-led model was acceptable and feasible to GPs and patients. It is possible to extend the scope of PN care to lead the routine clinical management of patients' stable chronic diseases. All GPs identified significant advantages to the model and elected to continue with the PN-led care after our study concluded.

  7. Remote Sensing-Derived Water Extent and Level to Constrain Hydraulic Flood Forecasting Models: Opportunities and Challenges

    Science.gov (United States)

    Grimaldi, Stefania; Li, Yuan; Pauwels, Valentijn R. N.; Walker, Jeffrey P.

    2016-09-01

    Accurate, precise and timely forecasts of flood wave arrival time, depth and velocity at each point of the floodplain are essential to reduce damage and save lives. Current computational capabilities support hydraulic models of increasing complexity over extended catchments. Yet a number of sources of uncertainty (e.g., input and boundary conditions, implementation data) may hinder the delivery of accurate predictions. Field gauging data of water levels and discharge have traditionally been used for hydraulic model calibration, validation and real-time constraint. However, the discrete spatial distribution of field data impedes the testing of the model skill at the two-dimensional scale. The increasing availability of spatially distributed remote sensing (RS) observations of flood extent and water level offers the opportunity for a comprehensive analysis of the predictive capability of hydraulic models. The adequate use of the large amount of information offered by RS observations triggers a series of challenging questions on the resolution, accuracy and frequency of acquisition of RS observations; on RS data processing algorithms; and on calibration, validation and data assimilation protocols. This paper presents a review of the availability of RS observations of flood extent and levels, and their use for calibration, validation and real-time constraint of hydraulic flood forecasting models. A number of conclusions and recommendations for future research are drawn with the aim of harmonising the pace of technological developments and their applications.

  8. Using occupancy and population models to assess habitat conservation opportunities for an isolated carnivore population

    Science.gov (United States)

    Wayne Spencer; Heather Rustigian-Romsos; James Strittholt; Robert Scheller; William Zielinski; Richard Truex

    2011-01-01

    An isolated population of the fisher (Martes pennanti) in the southern Sierra Nevada, California, is threatened by small size and habitat alteration from wildfires, fuels management, and other factors. We assessed the population’s status and conservation options for its habitat using a spatially explicit population model coupled with a...

  9. Meet the Molecules in Chocolate: Informal Opportunities for Building Thematic Molecular Models with Children

    Science.gov (United States)

    Amey, Jennifer R.; Fletcher, Matthew D.; Fletcher, Rachael V.; Jones, Alison; Roberts, Erica W.; Roberts, Ieuan O.

    2008-01-01

    We describe the development and use of a molecular model building activity with a chocolate theme, suitable for a public presentation of chemistry through interaction with visitors to science festivals and museums, and as a special classroom activity during science weeks, and so forth. (Contains 3 figures.)

  10. The Python Project: A Unique Model for Extending Research Opportunities to Undergraduate Students

    Science.gov (United States)

    Harvey, Pamela A.; Wall, Christopher; Luckey, Stephen W.; Langer, Stephen; Leinwand, Leslie A.

    2014-01-01

    Undergraduate science education curricula are traditionally composed of didactic instruction with a small number of laboratory courses that provide introductory training in research techniques. Research on learning methodologies suggests this model is relatively ineffective, whereas participation in independent research projects promotes enhanced…

  11. Incorporating Logistics in Freight Transport Demand Models: State-of-the-Art and Research Opportunities

    NARCIS (Netherlands)

    Tavasszy, L.A.; Ruijgrok, K.; Davydenko, I.

    2012-01-01

    Freight transport demand is a demand derived from all the activities needed to move goods between locations of production to locations of consumption, including trade, logistics and transportation. A good representation of logistics in freight transport demand models allows us to predict the effects

  12. Fundulus as the Premier Teleost Model in Environmental Biology: Opportunities for New Insights Using Genomics

    Science.gov (United States)

    A strong foundation of basic and applied research documents that the estuarine fish Fundulus heteroclitus and related species are unique laboratory and field models for understanding how individuals and populations interact with their environment. In this paper we summarize an ex...

  13. Method for identifying process reuse opportunities to enhance the operating model

    CSIR Research Space (South Africa)

    De Vries, M

    2011-12-01

    Full Text Available the volatility of strategy and suggests the use of an operating model (OM), which is a commitment to a way of doing business. The OM creates a company-wide vision for process standardization and data centralization and guides decisions about how a company...

  14. A window of opportunities : the contributions of land use modelling to societal learning

    NARCIS (Netherlands)

    Sterk, B.

    2007-01-01

    It has been argued that the management of land, whether at the field, farm or regional scale, can benefit from computer-based land use system analysis. As a result, a large number of computer-based models and tools have been produced over the past decades with the aim of providing support to policy

  15. Forest Conservation Opportunity Areas - Conservative Model (ECO_RES.COA_FORREST66)

    Science.gov (United States)

    This layer designates areas with potential for forest conservation. These are areas of natural or semi-natural forest land cover patches that area at least 395 meters away from roads and away from patch edges. OAs were modeled by creating distance grids using the National Land Cover Database and the Census Bureau's TIGER road files.

  16. Forest Conservation Opportunity Areas - Liberal Model (ECO_RES.COA_FORREST33)

    Science.gov (United States)

    This layer designates areas with potential for forest conservation. These are areas of natural or semi-natural forest land cover patches that are at least 75 meters away from roads and away from patch edges. OAs were modeled by creating distance grids using the National Land Cover Database and the Census Bureau's TIGER roads files.

  17. Meet the Molecules in Chocolate: Informal Opportunities for Building Thematic Molecular Models with Children

    Science.gov (United States)

    Amey, Jennifer R.; Fletcher, Matthew D.; Fletcher, Rachael V.; Jones, Alison; Roberts, Erica W.; Roberts, Ieuan O.

    2008-01-01

    We describe the development and use of a molecular model building activity with a chocolate theme, suitable for a public presentation of chemistry through interaction with visitors to science festivals and museums, and as a special classroom activity during science weeks, and so forth. (Contains 3 figures.)

  18. Sensitivity analysis in the WWTP modelling community – new opportunities and applications

    DEFF Research Database (Denmark)

    Sin, Gürkan; Ruano, M.V.; Neumann, Marc B.

    2010-01-01

    A mainstream viewpoint on sensitivity analysis in the wastewater modelling community is that it is a first-order differential analysis of outputs with respect to the parameters – typically obtained by perturbing one parameter at a time with a small factor. An alternative viewpoint on sensitivity ...

  19. The Python Project: A Unique Model for Extending Research Opportunities to Undergraduate Students

    Science.gov (United States)

    Harvey, Pamela A.; Wall, Christopher; Luckey, Stephen W.; Langer, Stephen; Leinwand, Leslie A.

    2014-01-01

    Undergraduate science education curricula are traditionally composed of didactic instruction with a small number of laboratory courses that provide introductory training in research techniques. Research on learning methodologies suggests this model is relatively ineffective, whereas participation in independent research projects promotes enhanced…

  20. A Modeling Framework for Supply Chain Simulation: Opportunities for Improved Decision Making

    NARCIS (Netherlands)

    Zee, van der D.J.; Vorst, van der J.G.A.J.

    2005-01-01

    Owing to its inherent modeling flexibility, simulation is often regarded as the proper means for supporting decision making on supply chain design. The ultimate success of supply chain simulation, however, is determined by a combination of the analyst's skills, the chain members' involvement, and th

  1. A modeling framework for supply chain simulation : opportunities for improved decision-making

    NARCIS (Netherlands)

    van der Zee, D.J.; van der Vorst, J.G.A.J.

    2005-01-01

    Owing to its inherent modeling flexibility, simulation is often regarded as the proper means for supporting decision making on supply chain design. The ultimate success of supply chain simulation, however, is determined by a combination of the analyst's skills, the chain members' involvement, and th

  2. Energy efficiency and renewable energy modeling with ETSAP TIAM - challenges, opportunities, and solutions

    DEFF Research Database (Denmark)

    Gregg, Jay Sterling; Balyk, Olexandr; Pérez, Cristian Hernán Cabrera

    The objectives of the Sustainable Energy for All (SE4ALL), a United Nations (UN) global initiative, are to achieve, by 2030: 1) universal access to modern energy services; 2) a doubling of the global rate of improvement in energy efficiency; and 3) a doubling of the share of renewable energy in t...... including updating data, setting constraints, and reporting on output. The presentation also addresses the addition of new model components such as traditional biomass and building energy efficiency....

  3. Modelling the migration opportunities of diadromous fish species along a gradient of dissolved oxygen concentration in a European tidal watershed

    Science.gov (United States)

    Maes, J.; Stevens, M.; Breine, J.

    2007-10-01

    The relationship between poor water quality and migration opportunities for fish remains poorly documented, although it is an essential research step in implementing EU water legislation. In this paper, we model the environmental constraints that control the movements of anadromous and catadromous fish populations that migrate through the tidal watershed of River Scheldt, a heavily impacted river basin in Western Europe. Local populations of sturgeon, sea lamprey, sea trout, Atlantic salmon, houting and allis shad were essentially extirpated around 1900. For remaining populations (flounder, three-spined stickleback, twaite shad, thinlip mullet, European eel and European smelt), a data driven logistic model was parameterized. The presence or absence of fish species in samples taken between 1995 and 2004 was modelled as a function of temperature, dissolved oxygen concentration, river flow and season. Probabilities to catch individuals from all diadromous species but three-spined stickleback increased as a function of the interaction between temperature and dissolved oxygen. The hypoxic zone situated in the freshwater tidal part of the estuary was an effective barrier for upstream migrating anadromous spawners since it blocked the entrance to historical spawning sites upstream. Similarly, habitat availability for catadromous fish was greatly reduced and restricted to lower brackish water parts of the estuary. The model was applied to infer preliminary dissolved oxygen criteria for diadromous fish, to make qualitative predictions about future changes in fish distribution given anticipated changes in water quality and to suggest necessary measures with respect to watershed management.

  4. Prospects and opportunities the implementation of effective management models at the enterprises of the Russian industry

    Directory of Open Access Journals (Sweden)

    E. S. Balashova

    2016-01-01

    Full Text Available In 2015 the recession of the Russian economy continues. Economic forecasts of 2016 made by influential rating agencies and the International Monetary Fund are analyzed. It is emphasized that the course of structural economic changes, selected by the Russian government actualizes the issue of increasing the competitiveness of Russian industry on a global level that, in turn, contributes to the implementation of effective management models at the enterprises and organization of internal processes. Positively recommended concept of lean production abroad became popular in Russia in early 2000’s. First successful example of its implementation – CJSC “Ford Motor Company” is considered. A large number of enterprises which represent state corporations “Rosteh” and “Rosatom”, industrial group “Basic element”, OJSC “Russian Railways” and which are individual major representatives of the Russian industrial sector are investigated. Different ways of development of lean production by Russian enterprises are analyzed and the most common way – independent interpretation and implementation is identified. Review of the tools of this management model used at the Russian enterprises is paid great attention. The prevalence of such tool as 5S (approximately 87,5%, because of its visible simplicity of understanding and ease of implementation is noted. The most important indicator – the economic effect of the introduction of the lean production concept at the enterprises of Russian industry in 2014 is analyzed. It is concluded that the economic result of the use of management model at Russian industrial enterprises is extremely low and varies at most about 1% of revenue. The obtained results demonstrate the prospects of further development of lean production and prove the possibility of achieving a high competitiveness of the domestic industrial sector of economy.

  5. Use of several Cloud Computing approaches for climate modelling: performance, costs and opportunities

    Science.gov (United States)

    Perez Montes, Diego A.; Añel Cabanelas, Juan A.; Wallom, David C. H.; Arribas, Alberto; Uhe, Peter; Caderno, Pablo V.; Pena, Tomas F.

    2017-04-01

    Cloud Computing is a technological option that offers great possibilities for modelling in geosciences. We have studied how two different climate models, HadAM3P-HadRM3P and CESM-WACCM, can be adapted in two different ways to run on Cloud Computing Environments from three different vendors: Amazon, Google and Microsoft. Also, we have evaluated qualitatively how the use of Cloud Computing can affect the allocation of resources by funding bodies and issues related to computing security, including scientific reproducibility. Our first experiments were developed using the well known ClimatePrediction.net (CPDN), that uses BOINC, over the infrastructure from two cloud providers, namely Microsoft Azure and Amazon Web Services (hereafter AWS). For this comparison we ran a set of thirteen month climate simulations for CPDN in Azure and AWS using a range of different virtual machines (VMs) for HadRM3P (50 km resolution over South America CORDEX region) nested in the global atmosphere-only model HadAM3P. These simulations were run on a single processor and took between 3 and 5 days to compute depending on the VM type. The last part of our simulation experiments was running WACCM over different VMS on the Google Compute Engine (GCE) and make a comparison with the supercomputer (SC) Finisterrae1 from the Centro de Supercomputacion de Galicia. It was shown that GCE gives better performance than the SC for smaller number of cores/MPI tasks but the model throughput shows clearly how the SC performance is better after approximately 100 cores (related with network speed and latency differences). From a cost point of view, Cloud Computing moves researchers from a traditional approach where experiments were limited by the available hardware resources to monetary resources (how many resources can be afforded). As there is an increasing movement and recommendation for budgeting HPC projects on this technology (budgets can be calculated in a more realistic way) we could see a shift on

  6. Sustainable Global Competitiveness Model as a New Strategic Opportunity for the Companies in Slovakia

    Directory of Open Access Journals (Sweden)

    Šnircová Jana

    2016-05-01

    Full Text Available Dealing with global competitiveness is nowadays the strategic issue for the Slovak companies in context of sustainability. It means for managers of company to define new future strategic goals, to identify current position in global market, primarily to focus the strategy on sustainable global competitiveness and to assess the competitiveness in new way regarding sustainability and social corporate responsibility. The aim of this paper is to present the contribution to holistic micro and macro economical view on competitiveness of company in context of sustainable development in global environment. The introduced sustainable global competitiveness model is based on our experiences within the research in manufacturing companies in Slovakia. It is a visualization of enterprise as a system with all relation performing in its environment. Sustainable global competitiveness model comprises the three pillar principle of the sustainable development, modified Porter´s value chain, and economical environment represented with Global Competitiveness Index (GCI and other factors of environment which influence the company.

  7. Modeling Post-death Transmission of Ebola: Challenges for Inference and Opportunities for Control

    Science.gov (United States)

    Weitz, Joshua S.; Dushoff, Jonathan

    2015-03-01

    Multiple epidemiological models have been proposed to predict the spread of Ebola in West Africa. These models include consideration of counter-measures meant to slow and, eventually, stop the spread of the disease. Here, we examine one component of Ebola dynamics that is of ongoing concern - the transmission of Ebola from the dead to the living. We do so by applying the toolkit of mathematical epidemiology to analyze the consequences of post-death transmission. We show that underlying disease parameters cannot be inferred with confidence from early-stage incidence data (that is, they are not ``identifiable'') because different parameter combinations can produce virtually the same epidemic trajectory. Despite this identifiability problem, we find robustly that inferences that don't account for post-death transmission tend to underestimate the basic reproductive number - thus, given the observed rate of epidemic growth, larger amounts of post-death transmission imply larger reproductive numbers. From a control perspective, we explain how improvements in reducing post-death transmission of Ebola may reduce the overall epidemic spread and scope substantially. Increased attention to the proportion of post-death transmission has the potential to aid both in projecting the course of the epidemic and in evaluating a portfolio of control strategies.

  8. Moving forward in circles: Challenges and opportunities in modeling population cycles

    Science.gov (United States)

    Barraquand, Frederic; Louca, Stilianos; Abbott, Karen C; Cobbold, Christina A; Cordoleani, Flora; DeAngelis, Don; Elderd, Bret D; Fox, Jeremy W; Greenwood, Priscilla; Hilker, Frank M; Murray, Dennis; Stieha, Christopher R; Taylor, Rachel A; Vitense, Kelsey; Wolkowicz, Gail; Tyson, Rebecca C

    2017-01-01

    Population cycling is a widespread phenomenon, observed across a multitude of taxa in both laboratory and natural conditions. Historically, the theory associated with population cycles was tightly linked to pairwise consumer–resource interactions and studied via deterministic models, but current empirical and theoretical research reveals a much richer basis for ecological cycles. Stochasticity and seasonality can modulate or create cyclic behaviour in non-intuitive ways, the high-dimensionality in ecological systems can profoundly influence cycling, and so can demographic structure and eco-evolutionary dynamics. An inclusive theory for population cycles, ranging from ecosystem-level to demographic modelling, grounded in observational or experimental data, is therefore necessary to better understand observed cyclical patterns. In turn, by gaining better insight into the drivers of population cycles, we can begin to understand the causes of cycle gain and loss, how biodiversity interacts with population cycling, and how to effectively manage wildly fluctuating populations, all of which are growing domains of ecological research.

  9. Police Training in El Salvador: Challenges and Opportunities in Promoting the Community Police Model

    Directory of Open Access Journals (Sweden)

    Luisa Carolina Arévalo Herrera

    2014-05-01

    Full Text Available The Peace Accords emphasized creating a new police force that would be diametrically opposite to previous security forces. This change would have to be expressed symbolically, and from the onset it would have to underscore the fact that the main weapon of the police would be intelligence. From its foundation to June 2011, a total of 30,344 people have graduated from the Academy. Currently, in the process of training new police with greater quality, and modernizing the entire police force, it faces the difficult challenge of adopting the Community Police philosophy to empower this model for action, promoting a new relationship between community and law enforcement, and between managers and operational personnel in the agency. Nevertheless,police training is not enough if there are no significantchanges in the organizational climate and culture within the law enforcement agency.DOI: http://dx.doi.org/10.5377/rpsp.v1i1.1390

  10. Center for Semiconductor Materials and Device Modeling: expanding collaborative research opportunities between government, academia, and industry

    Science.gov (United States)

    Perconti, Philip; Bedair, Sarah S.; Bajaj, Jagmohan; Schuster, Jonathan; Reed, Meredith

    2016-09-01

    To increase Soldier readiness and enhance situational understanding in ever-changing and complex environments, there is a need for rapid development and deployment of Army technologies utilizing sensors, photonics, and electronics. Fundamental aspects of these technologies include the research and development of semiconductor materials and devices which are ubiquitous in numerous applications. Since many Army technologies are considered niche, there is a lack of significant industry investment in the fundamental research and understanding of semiconductor technologies relevant to the Army. To address this issue, the US Army Research Laboratory is establishing a Center for Semiconductor Materials and Device Modeling and seeks to leverage expertise and resources across academia, government and industry. Several key research areas—highlighted and addressed in this paper—have been identified by ARL and external partners and will be pursued in a collaborative fashion by this Center. This paper will also address the mechanisms by which the Center is being established and will operate.

  11. Environmental Modeling, The Buffer Priority layers for Phosphorus / Sediment) Removal identify priority forest/grass buffer opportunities by subwatershed. Land use, hydrology, soil, and landscape characteristics were analyzed to rank buffer opportunities with high P/sed removal., Published in 2014, Smaller than 1:100000 scale, Maryland Department of Natural Resources (DNR).

    Data.gov (United States)

    NSGIC Education | GIS Inventory — Environmental Modeling dataset current as of 2014. The Buffer Priority layers for Phosphorus / Sediment) Removal identify priority forest/grass buffer opportunities...

  12. Artificial intelligence and exponential technologies business models evolution and new investment opportunities

    CERN Document Server

    Corea, Francesco

    2017-01-01

    Artificial Intelligence is a huge breakthrough technology that is changing our world. It requires some degrees of technical skills to be developed and understood, so in this book we are going to first of all define AI and categorize it with a non-technical language. We will explain how we reached this phase and what historically happened to artificial intelligence in the last century. Recent advancements in machine learning, neuroscience, and artificial intelligence technology will be addressed, and new business models introduced for and by artificial intelligence research will be analyzed. Finally, we will describe the investment landscape, through the quite comprehensive study of almost 14,000 AI companies and we will discuss important features and characteristics of both AI investors as well as investments. This is the “Internet of Thinks” era. AI is revolutionizing the world we live in. It is augmenting the human experiences, and it targets to amplify human intelligence in a future not so distant from...

  13. The application of 3D cell models to support drug safety assessment: opportunities & challenges.

    Science.gov (United States)

    Roth, Adrian; Singer, Thomas

    2014-04-01

    The selection of drug candidates early in development has become increasingly important to minimize the use of animals and to avoid costly failures of drugs later in development. In vitro systems to predict and assess organ toxicity have so far been of limited value due to difficulties in demonstrating in vivo-relevant toxicity at a cell culture level. To overcome the limitations of single-cell type monolayer cultures and short-lived primary cell preparations, researchers have created novel 3-dimensional culture systems which appear to more closely resemble in vivo biology. These could become a key for the pharmaceutical industry in the evaluation of drug candidates. However, the value and acceptance of those new models in standard drug safety applications have yet to be demonstrated. This review aims to provide an overview of the different approaches undertaken in the field of pre-clinical safety assessment, organ toxicity, in particular, with an emphasis on examples and technical challenges. Copyright © 2014 Elsevier B.V. All rights reserved.

  14. Three-dimensional in vitro cancer spheroid models for Photodynamic Therapy: Strengths and Opportunities

    Directory of Open Access Journals (Sweden)

    Conor L Evans

    2015-03-01

    Full Text Available Three dimensional, in vitro spheroid cultures offer considerable utility for the development and testing of anticancer photodynamic therapy regimens. More complex than monolayer cultures, three-dimensional spheroid systems replicate many of the important cell-cell and cell-matrix interactions that modulate treatment response in vivo. Simple enough to be grown by the thousands and small enough to be optically interrogated, spheroid cultures lend themselves to high-content and high-throughput imaging approaches. These advantages have enabled studies investigating photosensitizer uptake, spatiotemporal patterns of therapeutic response, alterations in oxygen diffusion and consumption during therapy, and the exploration of mechanisms that underlie therapeutic synergy. The use of quantitative imaging methods, in particular, has accelerated the pace of three-dimensional in vitro photodynamic therapy studies, enabling the rapid compilation of multiple treatment response parameters in a single experiment. Improvements in model cultures, the creation of new molecular probes of cell state and function, and innovations in imaging toolkits will be important for the advancement of spheroid culture systems for future photodynamic therapy studies.

  15. Seizing Opportunity

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    After the remarkable progress of the past five years, China has entered its new five-year plan period, starting from 2006, aiming to further its economic and social development. Though some are still talking about "China threat," many others consider the country's growth a huge opportunity. In an interview with People's Daily, Bill Fischer, former President of the Sino-European International Business School in Shanghai, comments on China's current development and also talks about problems the country fac...

  16. Evaluation of observed and modelled aerosol lifetimes using radioactive tracers of opportunity and an ensemble of 19 global models

    Science.gov (United States)

    Kristiansen, N. I.; Stohl, A.; Olivié, D. J. L.; Croft, B.; Søvde, O. A.; Klein, H.; Christoudias, T.; Kunkel, D.; Leadbetter, S. J.; Lee, Y. H.; Zhang, K.; Tsigaridis, K.; Bergman, T.; Evangeliou, N.; Wang, H.; Ma, P.-L.; Easter, R. C.; Rasch, P. J.; Liu, X.; Pitari, G.; Di Genova, G.; Zhao, S. Y.; Balkanski, Y.; Bauer, S. E.; Faluvegi, G. S.; Kokkola, H.; Martin, R. V.; Pierce, J. R.; Schulz, M.; Shindell, D.; Tost, H.; Zhang, H.

    2016-03-01

    Aerosols have important impacts on air quality and climate, but the processes affecting their removal from the atmosphere are not fully understood and are poorly constrained by observations. This makes modelled aerosol lifetimes uncertain. In this study, we make use of an observational constraint on aerosol lifetimes provided by radionuclide measurements and investigate the causes of differences within a set of global models. During the Fukushima Dai-Ichi nuclear power plant accident of March 2011, the radioactive isotopes cesium-137 (137Cs) and xenon-133 (133Xe) were released in large quantities. Cesium attached to particles in the ambient air, approximately according to their available aerosol surface area. 137Cs size distribution measurements taken close to the power plant suggested that accumulation-mode (AM) sulfate aerosols were the main carriers of cesium. Hence, 137Cs can be used as a proxy tracer for the AM sulfate aerosol's fate in the atmosphere. In contrast, the noble gas 133Xe behaves almost like a passive transport tracer. Global surface measurements of the two radioactive isotopes taken over several months after the release allow the derivation of a lifetime of the carrier aerosol. We compare this to the lifetimes simulated by 19 different atmospheric transport models initialized with identical emissions of 137Cs that were assigned to an aerosol tracer with each model's default properties of AM sulfate, and 133Xe emissions that were assigned to a passive tracer. We investigate to what extent the modelled sulfate tracer can reproduce the measurements, especially with respect to the observed loss of aerosol mass with time. Modelled 137Cs and 133Xe concentrations sampled at the same location and times as station measurements allow a direct comparison between measured and modelled aerosol lifetime. The e-folding lifetime τe, calculated from station measurement data taken between 2 and 9 weeks after the start of the emissions, is 14.3 days (95

  17. Evaluation of observed and modelled aerosol lifetimes using radioactive tracers of opportunity and an ensemble of 19 global models

    Directory of Open Access Journals (Sweden)

    N. I. Kristiansen

    2015-09-01

    Full Text Available Aerosols have important impacts on air quality and climate, but the processes affecting their removal from the atmosphere are not fully understood and are poorly constrained by observations. This makes modelled aerosol lifetimes uncertain. In this study, we make use of an observational constraint on aerosol lifetimes provided by radionuclide measurements and investigate the causes of differences within a set of global models. During the Fukushima Dai-Ichi nuclear power plant accident of March 2011, the radioactive isotopes cesium-137 (137Cs and xenon-133 (133Xe were released in large quantities. Cesium attached to particles in the ambient air, approximately according to their available aerosol surface area. 137Cs size distribution measurements taken close to the power plant suggested that accumulation-mode (AM sulphate aerosols were the main carriers for the cesium. Hence, 137Cs can be used as a proxy tracer for the AM sulphate aerosol's fate in the atmosphere. In contrast, the noble gas 133Xe behaves almost like a passive transport tracer. Global surface measurements of the two radioactive isotopes taken over several months after the release allow the derivation of a lifetime of the carrier aerosol. We compare this to the lifetimes simulated by 19 different atmospheric transport models initialized with identical emissions of 137Cs that were assigned to an aerosol tracer with each model's default properties of AM sulphate, and 133Xe emissions that were assigned to a passive tracer. We investigate to what extent the modelled sulphate tracer can reproduce the measurements, especially with respect to the observed loss of aerosol mass with time. Modelled 37Cs and 133Xe concentrations sampled at the same location and times as station measurements allow a direct comparison between measured and modelled aerosol lifetime. The e-folding lifetime τe, calculated from station measurement data taken between two and nine weeks after the start of the

  18. Modelling exposure opportunities

    DEFF Research Database (Denmark)

    Sabel, Clive E.; Gatrell, Anthony C.; Löytönen, Markku;

    2000-01-01

    emergence of the disease, with specific reference to the rare neurological condition, motor neurone disease (MND), using a dataset obtained from the Finnish Death Certificate registry, for MND deaths between the period 1985-1995. A space-time approach is adopted, whereby patterns in both time and space......This paper addresses the issues surrounding an individual's exposure to potential environmental risk factors, which can be implicated in the aetiology of a disease. We hope to further elucidate the 'lag' or latency period between the initial exposure to potential pathogens and the physical...

  19. Opportunities to enhance contribution of model forests in the sustainable forest resources management (example from Yalova Model Forest).

    Science.gov (United States)

    Bekiroğlu, Sultan; Özdemir, Mehmet; Özyürek, Ercan; Arslan, Avni

    2016-10-01

    Model forests are nongovernmental organizations at local, regional and international level which are mainly focused on reconciling the conflicts between the stakeholders. This is an innovative approach to organization, which has been receiving more and more attraction from increasing number of countries, which gradually increased the number of model forests for the last 25 years. If these organizations reach desired levels of structure, medium, impacts and assets their contribution in sustainable forest resources management will increase ipso facto. The very first model forest of Turkey was created in Yalova Province in 2010. Yalova Province has certain fundamental problems including but not limited to; population growth and unplanned urbanization caused by industrialization, uncontrolled increase in demand for fire wood and non-wooden products of forestry resources, questionable resource management decisions adopted in the past and low-income levels of the people especially those in the rural areas. The main objective of present case study is to analyze Yalova Model Forest (YMF) so as to determine the possible problems that may occur during implementation of sustainable management for forestry resources through a planning approach with multiple stakeholders. As a result of research, it has been revealed that YMF has certain significant structural, environmental and impact-related problems. In order to ensure continuity of YMF's contribution to sustainable forestry resources management, these problems need to be addressed promptly. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. Creating Innovative Opportunities

    DEFF Research Database (Denmark)

    Ljungberg, Daniel; McKelvey, Maureen; Lassen, Astrid Heidemann

    2012-01-01

    This paper develops lessons about how and why the founders and ventures involved in knowledge intensive entrepreneurship (KIE) manage the process of venture creation. The meta-analysis of the 86 case studies is based upon as conceptual model (from a systemic literature review), linked to illustra...... of knowledge networks to create innovative opportunities....

  1. A Spatially Based Area–Time Inundation Index Model Developed to Assess Habitat Opportunity in Tidal–Fluvial Wetlands and Restoration Sites

    Energy Technology Data Exchange (ETDEWEB)

    Coleman, Andre M.; Diefenderfer, Heida L.; Ward, Duane L.; Borde, Amy B.

    2015-09-01

    The hydrodynamics of tidal wetland areas in the lower Columbia River floodplain and estuary directly affect habitat opportunity for endangered salmonid fishes. Physical and biological structures and functions in the system are directly affected by inundation patterns influenced by tidal cycles, hydropower operations, river discharge, upriver water withdrawals, climate, and physical barriers such as dikes, culverts, and tide gates. Ongoing ecosystem restoration efforts are intended to increase the opportunity for salmon to access beneficial habitats by hydrologically reconnecting main-stem river channels and diked areas within the historical floodplain. To address the need to evaluate habitat opportunity, a geographic information system-based Area-Time Inundation Index Model (ATIIM) was developed. The ATIIM integrates in situ or modeled hourly water-surface elevation (WSE) data and advanced terrain processing of high-resolution elevation data. The ATIIM uses a spatially based wetted-area algorithm to determine site average bankfull elevation, two- and three-dimensional inundation extent, and other site metrics. Hydrological process metrics such as inundation frequency, duration, maximum area, and maximum frequency area can inform evaluation of proposed restoration sites; e.g., determine trade-offs between WSE and habitat opportunity, contrast alternative restoration designs, predict impacts of altered flow regimes, and estimate nutrient and biomass fluxes. In an adaptive management framework, this model can be used to provide standardized site comparisons and effectiveness monitoring of changes in the developmental trajectories of restoration sites. Results are presented for 11 wetlands representative of tidal marshes, tidal forested wetlands, and restoration sites.

  2. The role of ability, motivation, and opportunity to work in the transition from work to early retirement--testing and optimizing the Early Retirement Model.

    Science.gov (United States)

    de Wind, Astrid; Geuskens, Goedele A; Ybema, Jan Fekke; Bongers, Paulien M; van der Beek, Allard J

    2015-01-01

    Determinants in the domains health, job characteristics, skills, and social and financial factors may influence early retirement through three central explanatory variables, namely, the ability, motivation, and opportunity to work. Based on the literature, we created the Early Retirement Model. This study aims to investigate whether data support the model and how it could be improved. Employees aged 58-62 years (N=1862), who participated in the first three waves of the Dutch Study on Transitions in Employment, Ability and Motivation (STREAM) were included. Determinants were assessed at baseline, central explanatory variables after one year, and early retirement after two years. Structural equation modeling was applied. Testing the Early Retirement Model resulted in a model with good fit. Health, job characteristics, skills, and social and financial factors were related to the ability, motivation and/or opportunity to work (significant β range: 0.05-0.31). Lower work ability (β=-0.13) and less opportunity to work (attitude colleagues and supervisor about working until age 65: β=-0.24) predicted early retirement, whereas the motivation to work (work engagement) did not. The model could be improved by adding direct effects of three determinants on early retirement, ie, support of colleagues and supervisor (β=0.14), positive attitude of the partner with respect to early retirement (β=0.15), and not having a partner (β=-0.13). The Early Retirement Model was largely supported by the data but could be improved. The prolongation of working life might be promoted by work-related interventions focusing on health, work ability, the social work climate, social norms on prolonged careers, and the learning environment.

  3. Development of an instrument to assess the impact of an enhanced experiential model on pharmacy students' learning opportunities, skills and attitudes: A retrospective comparative-experimentalist study

    Directory of Open Access Journals (Sweden)

    Collins John B

    2008-04-01

    Full Text Available Abstract Background Pharmacy schools across North America have been charged to ensure their students are adequately skilled in the principles and practices of pharmaceutical care. Despite this mandate, a large percentage of students experience insufficient opportunities to practice the activities, tasks and processes essential to pharmaceutical care. The objective of this retrospective study of pharmacy students was to: (1 as "proof of concept", test the overall educational impact of an enhanced advanced pharmacy practice experiential (APPE model on student competencies; (2 develop an instrument to measure students' and preceptors' experiences; and (3 assess the psychometric properties of the instrument. Methods A comparative-experimental design, using student and preceptor surveys, was used to evaluate the impact of the enhanced community-based APPE over the traditional APPE model. The study was grounded in a 5-stage learning model: (1 an enhanced learning climate leads to (2 better utilization of learning opportunities, including (3 more frequent student/patient consultation, then to (4 improved skills acquisition, thence to (5 more favorable attitudes toward pharmaceutical care practice. The intervention included a one-day preceptor workshop, a comprehensive on-site student orientation and extending the experience from two four-week experiences in different pharmacies to one eight-week in one pharmacy. Results The 35 student and 38 preceptor survey results favored the enhanced model; with students conducting many more patient consultations and reporting greater skills improvement. In addition, the student self-assessment suggested changes in attitudes favoring pharmaceutical care principles. Psychometric testing showed the instrument to be sensitive, valid and reliable in ascertaining differences between the enhanced and traditional arms. Conclusion The enhanced experiential model positively affects learning opportunities and competency

  4. Developing a Model of Advanced Training to Promote Career Advancement for Certified Genetic Counselors: An Investigation of Expanded Skills, Advanced Training Paths, and Professional Opportunities.

    Science.gov (United States)

    Baty, Bonnie J; Trepanier, Angela; Bennett, Robin L; Davis, Claire; Erby, Lori; Hippman, Catriona; Lerner, Barbara; Matthews, Anne; Myers, Melanie F; Robbins, Carol B; Singletary, Claire N

    2016-08-01

    There are currently multiple paths through which genetic counselors can acquire advanced knowledge and skills. However, outside of continuing education opportunities, there are few formal training programs designed specifically for the advanced training of genetic counselors. In the genetic counseling profession, there is currently considerable debate about the paths that should be available to attain advanced skills, as well as the skills that might be needed for practice in the future. The Association of Genetic Counseling Program Directors (AGCPD) convened a national committee, the Committee on Advanced Training for Certified Genetic Counselors (CATCGC), to investigate varied paths to post-master's training and career development. The committee began its work by developing three related grids that view career advancement from the viewpoints of the skills needed to advance (skills), ways to obtain these skills (paths), and existing genetic counselor positions that offer career change or advancement (positions). Here we describe previous work related to genetic counselor career advancement, the charge of the CATCGC, our preliminary work in developing a model through which to view genetic counselor advanced training and career advancement opportunities, and our next steps in further developing and disseminating the model.

  5. Opportunity formation in social entrepreneurship

    DEFF Research Database (Denmark)

    Korsgaard, Steffen T.

    2011-01-01

    Purpose - This paper aims to explore the concept of opportunity and its role in social entrepreneurship processes. Design/methodology/approach - A single-case study of a sustainable community in Denmark. The data include interviews, documents and television programmes. Findings - The case study...... in the field of social entrepreneurship, while contributing to the development of the creation view of opportunities. Key words - Opportunity, Social entrepreneurship, Process, Sustainability, Case Study Paper type - Research paper...... finds that the opportunity takes a number of different forms in the process. These different forms are the result of a continuous mobilisation of actors. On the basis of these findings a model of social entrepreneurship processes is proposed, where the process is driven by mobilisation...

  6. Technology, Pedagogy, and Epistemology: Opportunities and Challenges of Using Computer Modeling and Simulation Tools in Elementary Science Methods

    Science.gov (United States)

    Schwarz, Christina V.; Meyer, Jason; Sharma, Ajay

    2007-01-01

    This study infused computer modeling and simulation tools in a 1-semester undergraduate elementary science methods course to advance preservice teachers' understandings of computer software use in science teaching and to help them learn important aspects of pedagogy and epistemology. Preservice teachers used computer modeling and simulation tools…

  7. Modelling Growth Curves in a Nondescript Italian Chicken Breed: an Opportunity to Improve Genetic and Feeding Strategies

    National Research Council Canada - National Science Library

    Selvaggi, Maria; Laudadio, Vito; Dario, Cataldo; Tufarelli, Vincenzo

    2015-01-01

    ... it. This study was carried out to estimate the parameters of logistic, Gompertz and Richards growth curve models in a nondescript chicken breed population from southern Italy to determine the goodness of fit...

  8. ALINET: a model for assessing energy conservation opportunities in the food processing industry. Final technical report, September 1977-December 1979

    Energy Technology Data Exchange (ETDEWEB)

    Levis, A H; Ducot, E R; Levis, I S; Webster, T F

    1979-12-01

    ALINET is a network model designed for the analysis of energy use in the food processing and distribution sector and for the evaluation of the potential effectiveness of energy conserving technologies. The conceptual framework of the model, as well as the design and implementation of the computer software are described. The wheat system at the national, state, and facility-specific level is used to illustrate the model's operation and use. A pilot project, carried out in cooperation with industry, is described in which energy use in (a) hard wheat milling, and (b) durum milling and pasta manufacture is analyzed. Finally, the introduction of an alternative technology for pasta drying is assessed in terms of energy conservation and cost. Recommendation for further applications and institutionalization of the model are made.

  9. Integrating a Detailed Agricultural Model in a Global Economic Framework: New methods for assessment of climate mitigation and adaptation opportunities

    Science.gov (United States)

    Thomson, A. M.; Izaurralde, R. C.; Calvin, K.; Zhang, X.; Wise, M.; West, T. O.

    2010-12-01

    Climate change and food security are global issues increasingly linked through human decision making that takes place across all scales from on-farm management actions to international climate negotiations. Understanding how agricultural systems can respond to climate change, through mitigation or adaptation, while still supplying sufficient food to feed a growing global population, thus requires a multi-sector tool in a global economic framework. Integrated assessment models are one such tool, however they are typically driven by historical aggregate statistics of production in combination with exogenous assumptions of future trends in agricultural productivity; they are not yet capable of exploring agricultural management practices as climate adaptation or mitigation strategies. Yet there are agricultural models capable of detailed biophysical modeling of farm management and climate impacts on crop yield, soil erosion and C and greenhouse gas emissions, although these are typically applied at point scales that are incompatible with coarse resolution integrated assessment modeling. To combine the relative strengths of these modeling systems, we are using the agricultural model EPIC (Environmental Policy Integrated Climate), applied in a geographic data framework for regional analyses, to provide input to the global economic model GCAM (Global Change Assessment Model). The initial phase of our approach focuses on a pilot region of the Midwest United States, a highly productive agricultural area. We apply EPIC, a point based biophysical process model, at 60 m spatial resolution within this domain and aggregate the results to GCAM agriculture and land use subregions for the United States. GCAM is then initialized with multiple management options for key food and bioenergy crops. Using EPIC to distinguish these management options based on grain yield, residue yield, soil C change and cost differences, GCAM then simulates the optimum distribution of the available

  10. Exotic models may offer unique opportunities to decipher specific scientific question: the case of Xenopus olfactory system.

    Science.gov (United States)

    Gascuel, Jean; Amano, Tosikazu

    2013-09-01

    The fact that olfactory systems are highly conserved in all animal species from insects to mammals allow the generalization of findings from one species to another. Most of our knowledge about the anatomy and physiology of the olfactory system comes from data obtained in a very limited number of biological models such as rodents, Zebrafish, Drosophila, and a worm, Caenorhabditis elegans. These models have proved useful to answer most questions in the field of olfaction, and thus concentrating on these few models appear to be a pragmatic strategy. However, the diversity of the organization and physiology of the olfactory system amongst phyla appear to be greater than generally assumed and the four models alone may not be sufficient to address all the questions arising from the study of olfaction. In this article, we will illustrate the idea that we should take advantage of biological diversity to address specific scientific questions and will show that the Xenopus olfactory system is a very good model to investigate: first, olfaction in aerial versus aquatic conditions and second, mechanisms underlying postnatal reorganization of the olfactory system especially those controlled by tyroxine hormone.

  11. Modeling and Simulation of Scalable Cloud Computing Environments and the CloudSim Toolkit: Challenges and Opportunities

    CERN Document Server

    Buyya, Rajkumar; Calheiros, Rodrigo N

    2009-01-01

    Cloud computing aims to power the next generation data centers and enables application service providers to lease data center capabilities for deploying applications depending on user QoS (Quality of Service) requirements. Cloud applications have different composition, configuration, and deployment requirements. Quantifying the performance of resource allocation policies and application scheduling algorithms at finer details in Cloud computing environments for different application and service models under varying load, energy performance (power consumption, heat dissipation), and system size is a challenging problem to tackle. To simplify this process, in this paper we propose CloudSim: an extensible simulation toolkit that enables modelling and simulation of Cloud computing environments. The CloudSim toolkit supports modelling and creation of one or more virtual machines (VMs) on a simulated node of a Data Center, jobs, and their mapping to suitable VMs. It also allows simulation of multiple Data Centers to...

  12. Internal steam reforming in solid oxide fuel cells: Status and opportunities of kinetic studies and their impact on modelling

    DEFF Research Database (Denmark)

    Mogensen, David; Grunwaldt, J.-D.; Hendriksen, Peter Vang;

    2011-01-01

    of such a system require SOFC models that include accurate description of the steam reforming rate. The objective of this article is to review the reported kinetic expressions for the steam reforming reaction. Extensive work has been performed on traditional catalysts for steam reforming. Because of differences...

  13. The effects of the use of a conversational model and opportunities for reflections in computer-based role playing

    NARCIS (Netherlands)

    Holsbrink-Engels, Geralien A.

    1997-01-01

    This study examined the effects of an instructional program on 21-year-old students' interpersonal skills development (N = 104). The HyperCard 2.1 program ¿Telling bad news¿ could contain a conversational model that informed students about the main moments and actions in conducting a bad-news conver

  14. Rewriting the Opportunity Theory

    DEFF Research Database (Denmark)

    Korsgaard, Steffen T.

    The aim of this paper is to further the discussion of opportunity theory by discussing its ontological and epistemological underpinnings, which have been neglected in previous discussions. The idea that opportunities have an objective component is critically examined drawing on insights from social...... constructionism. It is argued that opportunity theory needs to be rewritten....

  15. Opportunity Cost: A Reexamination

    Science.gov (United States)

    Parkin, Michael

    2016-01-01

    Is opportunity cost an ambiguous and arbitrary concept or a simple, straightforward, and fruitful one? This reexamination of opportunity cost addresses this question, and shows that opportunity cost is an ambiguous concept because "two" definitions are in widespread use. One of the definitions is indeed simple, fruitful, and one that…

  16. Rewriting the Opportunity Theory

    DEFF Research Database (Denmark)

    Korsgaard, Steffen T.

    The aim of this paper is to further the discussion of opportunity theory by discussing its ontological and epistemological underpinnings, which have been neglected in previous discussions. The idea that opportunities have an objective component is critically examined drawing on insights from social...... constructionism. It is argued that opportunity theory needs to be rewritten....

  17. Missed opportunities in the DSM-5 Section III personality disorder model: commentary on "personality disorders are the vanguard of the post-DSM-5.0 era".

    Science.gov (United States)

    Miller, Joshua D; Lynam, Donald R

    2013-10-01

    Comments on an article by Krueger (see record 2013-45025-008). The current authors appreciate the opportunity to comment on Krueger's article. They remark that as a member of the DSM-5 (American Psychiatric Association, 2013) Personality and Personality Disorders Work Group (PPDWG), he is in a unique position to describe the process surrounding the deliberations of the PPDWG and why their model was placed in Section III. Whereas Krueger offers that too much openness and contentiousness in the personality and personality disorder (PD) field were responsible for the difficulties faced by the DSM-5 PPDWG proposal, the current authors suggest another condition that may have been at play: myopia. The current authors discuss several shortsighted decisions made by the PPDWG that may have contributed to the disappointing outcome. Specifically, they describe ways in which the PPDWG ignored large bodies of extant research that could have guided and supported the proposal, inoculating it against many of the most damning critiques.

  18. Human pluripotent stem cell models of autism spectrum disorder: emerging frontiers, opportunities, and challenges towards neuronal networks in a dish

    OpenAIRE

    Aigner, Stefan; Heckel, Tobias; Zhang, Jitao D.; Andreae, Laura C.; Jagasia, Ravi

    2013-01-01

    Autism spectrum disorder (ASD) is characterized by deficits in language development and social cognition and the manifestation of repetitive and restrictive behaviors. Despite recent major advances, our understanding of the pathophysiological mechanisms leading to ASD is limited. Although most ASD cases have unknown genetic underpinnings, animal and human cellular models of several rare, genetically defined syndromic forms of ASD have provided evidence for shared pathophysiological mechanisms...

  19. Marketing Opportunities in the Digital World.

    Science.gov (United States)

    Kiani, G. Reza

    1998-01-01

    Addresses the opportunities offered by the Web to marketers. Considers the Web as a two-way communication model in which four different communication states can take place. Suggests the necessity of new concepts and models for marketers to manage their Web sites, and presents opportunities supporting the marketers' objectives in the new…

  20. A multi-scale mathematical modeling framework to investigate anti-viral therapeutic opportunities in targeting HIV-1 accessory proteins.

    Science.gov (United States)

    Suryawanshi, Gajendra W; Hoffmann, Alexander

    2015-12-07

    Human immunodeficiency virus-1 (HIV-1) employs accessory proteins to evade innate immune responses by neutralizing the anti-viral activity of host restriction factors. Apolipoprotein B mRNA-editing enzyme 3G (APOBEC3G, A3G) and bone marrow stromal cell antigen 2 (BST2) are host resistance factors that potentially inhibit HIV-1 infection. BST2 reduces viral production by tethering budding HIV-1 particles to virus producing cells, while A3G inhibits the reverse transcription (RT) process and induces viral genome hypermutation through cytidine deamination, generating fewer replication competent progeny virus. Two HIV-1 proteins counter these cellular restriction factors: Vpu, which reduces surface BST2, and Vif, which degrades cellular A3G. The contest between these host and viral proteins influences whether HIV-1 infection is established and progresses towards AIDS. In this work, we present an age-structured multi-scale viral dynamics model of in vivo HIV-1 infection. We integrated the intracellular dynamics of anti-viral activity of the host factors and their neutralization by HIV-1 accessory proteins into the virus/cell population dynamics model. We calculate the basic reproductive ratio (Ro) as a function of host-viral protein interaction coefficients, and numerically simulated the multi-scale model to understand HIV-1 dynamics following host factor-induced perturbations. We found that reducing the influence of Vpu triggers a drop in Ro, revealing the impact of BST2 on viral infection control. Reducing Vif׳s effect reveals the restrictive efficacy of A3G in blocking RT and in inducing lethal hypermutations, however, neither of these factors alone is sufficient to fully restrict HIV-1 infection. Interestingly, our model further predicts that BST2 and A3G function synergistically, and delineates their relative contribution in limiting HIV-1 infection and disease progression. We provide a robust modeling framework for devising novel combination therapies that target

  1. ANALYSIS OF EXISTING DEFECTS OF THE RUSSIAN BUSINESS EDUCATION AND OPPORTUNITIES OF TRANSITION TO A NEW MODEL TRAINING

    Directory of Open Access Journals (Sweden)

    Larin S. N.

    2016-04-01

    Full Text Available Studying the problems of the development of Russian business education today seems urgent in view of the serious impact of globalization factors on world markets, as well as taking into account the factors of global economic recession and to the undeclared war sanctions restrictions against the Russian economy and not having under itself no justification other than political. The article presents the results of the analysis of positive and negative factors in the development of the Russian business education, because of which it was concluded, that for the further development of the Russian system of business education needs a new approach. It should be based on the formation of the conceptual model, taking into account the current realities in the Russian economy. The authors set out to become the key provisions of the new approach, namely to ensure the growth of professional and specialist competencies required functionality; the study of «effective practical techniques», a reasonable reduction of the duration of the MBA program of study; distribution of specialists trained in powers depending on their positions. The above provisions allowed forming a conceptual model of business education, which is based on four practical degree professional training laid. In addition, the article justified criteria for evaluating the quality and composition requirements for modern business education program. The proposed in the article new approach and the conceptual model of the development of Russian business education are targeted at practitioners who want to gain more knowledge in a limited period and very reasonable cost of education. The further development of the Russian business education system in the very near future will show the validity of this approach

  2. Concurrent sourcing and external supplier opportunism

    DEFF Research Database (Denmark)

    Mols, Niels Peter

    When a firm simultaneously makes and buys the same components then the firm uses concurrent sourcing. This paper presents an agency model for explaining how and when concurrent sourcing reduces the likelihood of external supplier opportunism. In the proposed model, the external supplier’s expected...... costs of opportunism are determined as a product of four factors. The four factors are: likelihood of discovering supplier opportunism, buyer’s internalized quantity as reaction to supplier opportunism, asset specificity of external supplier’s investments, and multiplicator effects. Each...

  3. A display model for the TOU of PLATO: just a cool toy or a benchmark of opportunities?

    Science.gov (United States)

    Dima, M.; Greggio, D.; Bergomi, M.; Biondi, F.; Farinato, J.; Farisato, G.; Magrin, D.; Lessio, L.; Marafatto, L.; Munari, M.; Pagano, I.; Ragazzoni, R.; Viotto, V.; Piazza, D.

    2016-07-01

    We produced a "toy-model" of one Telescope Optical Unit of PLATO, the Medium sized mission selected by ESA to fly in 2024. This is a six lenses dioptric very wide field camera with a window in front to take care of radiation impact on the first lens whose optical glass cannot be replaced with a radiation hardened one. The main aim of this project is just to produce a "cool" model for display purposes, in which one can "explore" the details of the inside through some openings in the tube, in order to visually inspect some of the fine details of the opto-mechanics. While its didactic and advertising role is out of doubt, during its construction we realized that some interesting outcome can be of some relevance for the project itself and that some findings could be useful, in order to assess the ability of producing with the same technology some (of course of much more modest quality) optical systems. In this context, we immediately dropped the option of producing the lenses with opaque material painted with a color resembling a refractive material (like blue for instance) and decided to actually produce them with transparent plastic. Furthermore the surfaces are then finely polished in order to give them basic optical properties. Such an optical system has only very coarsely the converging properties of the original nominal design for a number of reasons: the refractive indexes are not the nominal ones, the quality of the surfaces and their nominal values are only roughly, within a few percent, the targeted one, and the way the surfaces are built up makes them prone to some diffraction effects. However, the bulk of the lens and the surface roughness will give a large magnification of the scattering effects that will be experienced, at a much lower level, on the actual flight model. We investigated through propagation of a laser beam and by digital camera the main stray light modes that this toymodel offers. In other words, the model amplifies, to a large extent, the

  4. A Fuzzy ANP Model Integrated with Benefits, Opportunities, Costs, and Risks to Prioritize Intelligent Power Grid Systems

    Directory of Open Access Journals (Sweden)

    Hsing Hung Chen

    2013-01-01

    Full Text Available Although growth of renewable energy is envisaged, many concerns are critical like the ability to maintain the balance between demands and supply and the variability, noncontrollability, and flexibility of the sources. Then, what will be the future concerns about the main composition of intelligent power grid systems in the future? There is no such research tackled before. Thus, this paper first finds critical success criteria of intelligent power grid systems and then constructs a multiple criteria and decision making model to help in identifying the suitable trends under complex economic performance, environmental impacts, and rapid technological and marketing changes. After empirical demonstration, the paper summarizes that the most suitable composition of future intelligent power grid systems should be constituted by “DHT” P2P grid, “C&D workflow” P2P scheduling, “GARCM” trustworthy P2P grid, and “multipurpose” grid applications in the future.

  5. Individual differences and the characterization of animal models of psychopathology: a strong challenge and a good opportunity

    Directory of Open Access Journals (Sweden)

    Antonio eArmario

    2013-11-01

    Full Text Available Despite the development of valuable new techniques (i.e. genetics, neuroimage for the study of the neurobiological substrate of psychiatric diseases, there are strong limitations in the information that can be gathered from human studies. It is thus critical to develop appropriate animal models of psychiatric diseases to characterize their putative biological bases and the development of new therapeutic strategies. The present review tries to offer a general perspective and several examples of how individual differences in animals can contribute to explain differential susceptibility to develop behavioural alterations, but also emphasizes methodological problems that can lead to inappropriate or over-simplistic interpretations. A critical analysis of the approaches currently used could contribute to obtain more reliable data and allow taking full advantage of new and sophisticated technologies. The discussion is mainly focused on anxiety-like and to a lower extent on depression-like behaviour in rodents.

  6. Suborbital Research and Development Opportunities

    Science.gov (United States)

    Davis, Jeffrey R.

    2011-01-01

    This slide presentation reviews the new strategies for problem solving in the life sciences in the suborbital realm. Topics covered are: an overview of the space life sciences, the strategic initiatives that the Space Life Sciences organization engaged in, and the new business model that these initiatives were developed. Several opportunities for research are also reviewed.

  7. Key Challenges and Opportunities Associated with the Use of In Vitro Models to Detect Human DILI: Integrated Risk Assessment and Mitigation Plans

    Directory of Open Access Journals (Sweden)

    Franck A. Atienzar

    2016-01-01

    Full Text Available Drug-induced liver injury (DILI is a major cause of late-stage clinical drug attrition, market withdrawal, black-box warnings, and acute liver failure. Consequently, it has been an area of focus for toxicologists and clinicians for several decades. In spite of considerable efforts, limited improvements in DILI prediction have been made and efforts to improve existing preclinical models or develop new test systems remain a high priority. While prediction of intrinsic DILI has improved, identifying compounds with a risk for idiosyncratic DILI (iDILI remains extremely challenging because of the lack of a clear mechanistic understanding and the multifactorial pathogenesis of idiosyncratic drug reactions. Well-defined clinical diagnostic criteria and risk factors are also missing. This paper summarizes key data interpretation challenges, practical considerations, model limitations, and the need for an integrated risk assessment. As demonstrated through selected initiatives to address other types of toxicities, opportunities exist however for improvement, especially through better concerted efforts at harmonization of current, emerging and novel in vitro systems or through the establishment of strategies for implementation of preclinical DILI models across the pharmaceutical industry. Perspectives on the incorporation of newer technologies and the value of precompetitive consortia to identify useful practices are also discussed.

  8. Key Challenges and Opportunities Associated with the Use of In Vitro Models to Detect Human DILI: Integrated Risk Assessment and Mitigation Plans

    Science.gov (United States)

    Blomme, Eric A.; Hewitt, Philip; Kenna, J. Gerry; Labbe, Gilles; Moulin, Frederic; Pognan, Francois; Roth, Adrian B.; Suter-Dick, Laura; Ukairo, Okechukwu; Weaver, Richard J.; Will, Yvonne; Dambach, Donna M.

    2016-01-01

    Drug-induced liver injury (DILI) is a major cause of late-stage clinical drug attrition, market withdrawal, black-box warnings, and acute liver failure. Consequently, it has been an area of focus for toxicologists and clinicians for several decades. In spite of considerable efforts, limited improvements in DILI prediction have been made and efforts to improve existing preclinical models or develop new test systems remain a high priority. While prediction of intrinsic DILI has improved, identifying compounds with a risk for idiosyncratic DILI (iDILI) remains extremely challenging because of the lack of a clear mechanistic understanding and the multifactorial pathogenesis of idiosyncratic drug reactions. Well-defined clinical diagnostic criteria and risk factors are also missing. This paper summarizes key data interpretation challenges, practical considerations, model limitations, and the need for an integrated risk assessment. As demonstrated through selected initiatives to address other types of toxicities, opportunities exist however for improvement, especially through better concerted efforts at harmonization of current, emerging and novel in vitro systems or through the establishment of strategies for implementation of preclinical DILI models across the pharmaceutical industry. Perspectives on the incorporation of newer technologies and the value of precompetitive consortia to identify useful practices are also discussed. PMID:27689095

  9. “CYTOKINE” MODEL OF PATHOGENESIS OF CHRONIC HEART FAILURE AND THE OPPORTUNITIES OF NEW THERAPEUTIC STRATEGY IN DECOMPENSATED PATIENTS

    Directory of Open Access Journals (Sweden)

    U. A. Vasuk

    2006-01-01

    Full Text Available Neurohumoral model of pathogenesis of chronic heart failure (CHF made it possible to develop new therapeutic approaches in patients with CHF . However , it became obvious that the ways of activation of neurohumoral systems in CHF are much more complicated. The increase in local synthesis of hormones causes the activation of inflammatory cytokines and protooncogenes, which have various negative effects. This allowed formulating immunoinflammatory conception of CHF pathogenesis, according to which the increase in interleukine-6 blood level is the marker of unfavorable prognosis for CHF , and the level of tumor necrosis factor-α (TNF-α straightly correlates with severity of clinical condition and neurohumoral activity in CHF . The growth of TNF-α in CHF progressing as well as its reduction in successful treatment do not exclude the probability of positive effect of therapy , focused on the reduction of TNF-α concentration. The pathogenesis peculiarities of CHF including cytokine aggression demand the necessity of development of new therapy approaches with the use of cytokine system modulators.

  10. A zebrafish model of congenital disorders of glycosylation with phosphomannose isomerase deficiency reveals an early opportunity for corrective mannose supplementation

    Directory of Open Access Journals (Sweden)

    Jaime Chu

    2013-01-01

    Individuals with congenital disorders of glycosylation (CDG have recessive mutations in genes required for protein N-glycosylation, resulting in multi-systemic disease. Despite the well-characterized biochemical consequences in these individuals, the underlying cellular defects that contribute to CDG are not well understood. Synthesis of the lipid-linked oligosaccharide (LLO, which serves as the sugar donor for the N-glycosylation of secretory proteins, requires conversion of fructose-6-phosphate to mannose-6-phosphate via the phosphomannose isomerase (MPI enzyme. Individuals who are deficient in MPI present with bleeding, diarrhea, edema, gastrointestinal bleeding and liver fibrosis. MPI-CDG patients can be treated with oral mannose supplements, which is converted to mannose-6-phosphate through a minor complementary metabolic pathway, restoring protein glycosylation and ameliorating most symptoms, although liver disease continues to progress. Because Mpi deletion in mice causes early embryonic lethality and thus is difficult to study, we used zebrafish to establish a model of MPI-CDG. We used a morpholino to block mpi mRNA translation and established a concentration that consistently yielded 13% residual Mpi enzyme activity at 4 days post-fertilization (dpf, which is within the range of MPI activity detected in fibroblasts from MPI-CDG patients. Fluorophore-assisted carbohydrate electrophoresis detected decreased LLO and N-glycans in mpi morphants. These deficiencies resulted in 50% embryonic lethality by 4 dpf. Multi-systemic abnormalities, including small eyes, dysmorphic jaws, pericardial edema, a small liver and curled tails, occurred in 82% of the surviving larvae. Importantly, these phenotypes could be rescued with mannose supplementation. Thus, parallel processes in fish and humans contribute to the phenotypes caused by Mpi depletion. Interestingly, mannose was only effective if provided prior to 24 hpf. These data provide insight into treatment efficacy

  11. Social problems as sources of opportunity – antecedents of social entrepreneurship opportunities

    Directory of Open Access Journals (Sweden)

    Agnieszka Żur

    2016-02-01

    Full Text Available Objective: Based on extensive literature review, this paper aims to establish if, why and how, in given environmental and market contexts, social entrepreneurship (SE opportunities are discovered and exploited. It positions social problems as sources of entrepreneurial opportunity. The article presents an integrated process-based view of SE opportunity antecedents and concludes with a dynamic model of SE opportunity. Research Design & Methods: To fulfil its goal, the paper establishes opportunity as unit of research and explores the dynamics of opportunity recognition. To identify the components of SE opportunity through a process-based view, the study follows the steps of critical literature review method. The literature review follows with logical reasoning and inference, which results in the formulation of a model proposition of social entrepreneurship opportunity. Findings: The paper presents a holistic perspective on opportunity antecedents in SE context and introduces social problems, information, social awareness and entrepreneurial mindset  as fundamental components of social entrepreneurship opportunity equation. Implications & Recommendations: It is necessary to remember for policy makers, investors and partners involved within the social sector, that social problems can be the source of entrepreneurial opportunity. Training, assisting and engaging socially aware entrepreneurs is a promising line of development for all communities. Contribution & Value Added: The major contribution of this study lies in extending the existing body of social entrepreneurship research by providing a new perspective, placing social problem as opportunity in the centre of the discussion.

  12. Modelling height to diameter ratio – an opportunity to increase Norway spruce stand stability in the Western Carpathians

    Directory of Open Access Journals (Sweden)

    Bošeľa Michal

    2014-06-01

    Full Text Available Smrek je jednou z najrozšírenejších a ekonomicky najdôležitejších ihličnatých drevín v Európe. Taktiež je drevinou veľmi často poškodzovanou vetrovými kalamitami. Štíhlostný kvocient (pomer výšky a hrúbky stromu sa považuje za vhodný indikátor statickej stability jednotlivých stromov a porastov. Preto cieľom práce bola identifikácia hlavných faktorov, ktoré majú významný vplyv na hodnoty kvocientu. Jednoduchý model bol vytvorený ako pomôcka pre lesníka pri rozhodovaní o intenzite prebierok v smrekových porastoch s cieľom potenciálneho zvýšenia statickej stability a zachovania optimálnej produkcie. Využili sa údaje Národnej inventarizácie a monitoringu lesov SR (260 plôch a taktiež údaje z predchádzajúcich výskumných projektov (48 plôch tak aby reprezentovali čo najširšie rozpätie ekologických podmienok, v ktorých smrek v súčasnosti rastie. Výsledky ukázali, že najvýznamnejšími ekologickými faktormi boli: nadmorská výška a bonita stanovišťa. Taktiež niektoré porastové charakteristiky sa významne podieľali na variabilite kvocientu: podiel koruny z výšky stromu, hustota porastu a stredná porastová výška reprezentujúca rastovú fázu porastu. Výsledky ďalej preukázali, že ekologické podmienky sú významnejšie ako porastové charakteristiky, a preto tieto treba brať do úvahy pri rozhodovacom procese. To znamená, že ak sa porast nachádza na pre smrek veľmi bonitnom stanovišti, sú potrebné silnejšie prebierky od mladých rastových fáz, aby sa ovplyvňovaním hrúbkového prírastku vyrovnal vplyv rýchleho výškového rastu. Zároveň je dôležitá rozdielna intenzita výškového a hrúbkového rastu počas vývoja porastu

  13. Using Verification Code with Opportunity Model Based on CAPTCHA%基于CAPTCHA技术的挑战信息使用时机模型

    Institute of Scientific and Technical Information of China (English)

    朴顺姬; 戴德伟

    2012-01-01

    Rational use of verification code for the purpose of inhibiting the spread of the virus worm,the use of mathematical modeling methods to build a verification code uses opportunity mathematic model based CAPTCHA.Improvement strategy is proposed to make up an increase of the burden of customers and the network load for CAPTCHA.Thereby it is a qualitative analysis of the best time to use verification code.%为了合理使用挑战信息并达到抑制蠕虫病毒传播的目的,采用数学建模方法建立一个基于CAPTCHA技术的挑战信息使用时机数学模型.针对CAPTCHA技术增加了用户负担和网络负载的不足,提出了改进策略,要找到一个合适的时间发送挑战信息,从而定性的分析了使用挑战信息的最佳时机.

  14. Genetic backgrounds and modifier genes of NTD mouse models: An opportunity for greater understanding of the multifactorial etiology of neural tube defects.

    Science.gov (United States)

    Leduc, Renee Y M; Singh, Parmveer; McDermid, Heather E

    2016-10-21

    Neurulation, the early embryonic process of forming the presumptive brain and spinal cord, is highly complex and involves hundreds of genes in multiple genetic pathways. Mice have long served as a genetic model for studying human neurulation, and the resulting neural tube defects (NTDs) that arise when neurulation is disrupted. Because mice appear to show mostly single gene inheritance for NTDs and humans show multifactorial inheritance, mice sometimes have been characterized as a simpler model for the identification and study of NTD genes. But are they a simple model? When viewed on different genetic backgrounds, many genes show significant variation in the penetrance and expressivity of NTD phenotypes, suggesting the presence of modifier loci that interact with the target gene to affect the phenotypic expression. Looking at mutations on different genetic backgrounds provides us with an opportunity to explore these complex genetic interactions, which are likely to better emulate similar processes in human neurulation. Here, we review NTD genes known to show strain-specific phenotypic variation. We focus particularly on the gene Cecr2, which is studied using both a hypomorphic and a presumptive null mutation on two different backgrounds: one susceptible (BALB/c) and one resistant (FVB/N) to NTDs. This strain difference has led to a search for genetic modifiers within a region on murine chromosome 19. Understanding how genetic variants alter the phenotypic outcome in NTD mouse models will help to direct future studies in humans, particularly now that more genome wide sequencing approaches are being used. Birth Defects Research (Part A), 2016. © 2016 Wiley Periodicals, Inc.

  15. Altmetric opportunities for Libraries

    NARCIS (Netherlands)

    Gerritsma, W.

    2015-01-01

    Just over five years ago the concept of altmetrics was minted. For libraries and librarians this has brought a new plethora of opportunities. In the first place there is the traditional extension role. Outreach opportunities on the subject of altmetrics are manyfold, and librarians could seize the o

  16. Equal opportunities in diversity

    CERN Multimedia

    Laëtitia Pedroso

    2010-01-01

    Promoting equal opportunities at CERN and advising the Director-General on all related matters is the task of the Equal Opportunities Officer, Doris Chromek-Burckhart, and Tim Smith, chair of the Equal Opportunities Advisory Panel. Changes are being introduced: in future, the focus of their work will be broadened to cover all aspects of diversity promotion.   The term "equal opportunities" has always been broader in scope than the equal treatment of men and women but this is what it has traditionally been confined to in practice. "We wanted to change how people see our mission", explains Doris Chromek-Burckhart. The word "diversity" has much wider connotations than "equal opportunities" and makes it clearer that we are also dealing with differences in nationality, religion, age, culture and physical ability”. Getting away from the old clichés is vital to ensuring equal treatment for everyone. The diversit...

  17. Opportunity Identification and Creation as Factors of Firm Internationalisation

    Directory of Open Access Journals (Sweden)

    Agnieszka Żur

    2015-06-01

    and accuracy in opportunity identification. The article presents an integrated process-based view of opportunity antecedents and concludes with a dynamic cyclical path-dependent model of opportunity-based view of firm internationalisation. Hopefully, the proposed model can serve as a useful lens for hypotheses formulation and testing within the research on firm internationalisation determinants.

  18. Equal Opportunities Questionnaire

    CERN Document Server

    2007-01-01

    The initiative to promote Equal Opportunities at CERN started in 1993. The first Equal Opportunities Officer was appointed in 1996, which was followed by the creation of the Equal Opportunities Advisory Panel in 1998. Initially the concern was mainly the fair treatment of women in the work-place. Today the emphasis has evolved to ensuring that diversity is used to increase creativity and productivity in the work-place. In order to ensure that all aspects of Equal Opportunities and Diversity are covered, CERN’s Equal Opportunities team has prepared a survey to obtain your input. Your answers are confidential and will only be used for generating statistics. The questionnaire is on-line and can be accessed via: https://espace.cern.ch/EOQ. We hope that you will take a few minutes of your time to give your input and would be grateful if you could reply before 15/10/07. For further information about Equal Opportunities at CERN see: http://cern.ch/equal-opportunities The Equa...

  19. Equal Opportunities Questionnaire

    CERN Document Server

    2007-01-01

    The initiative to promote Equal Opportunities at CERN started in 1993. The first Equal Opportunities Officer was appointed in 1996 followed by the creation of the Equal Opportunities Advisory Panel in 1998. Initially the concern was mainly the fair treatment of women in the work-place. Today the emphasis has evolved to ensuring that diversity is used to increase creativity and productivity in the work-place. In order to ensure that all aspects of Equal Opportunities and Diversity are covered, CERN’s Equal Opportunities team has prepared a survey to obtain your input. Your answers are confidential and will only be used for generating statistics. The questionnaire is on-line and can be accessed via: https://espace.cern.ch/EOQ. We hope that you will take a few minutes of your time to give your input and would be grateful if you could reply before 15/10/07. For further information about Equal Opportunities at CERN see: http://cern.ch/equal-opportunities The Equal Opportuni...

  20. On inclusion of water resource management in Earth System models – Part 2: Representation of water supply and allocation and opportunities for improved modeling

    Directory of Open Access Journals (Sweden)

    A. Nazemi

    2014-07-01

    Full Text Available Human water use has significantly increased during the recent past. Water allocation from surface and groundwater sources has altered terrestrial discharge and storage, with large variability in time and space. Water supply and allocation, therefore, should be considered with water demand and appropriately included in large-scale models to address various online and offline implications, with or without considering possible climate interactions. Here, we review the algorithms developed to represent the elements of water supply and allocation in large-scale models, in particular Land Surface Schemes and Global Hydrologic Models. We noted that some potentially-important online implications, such as the effects of large reservoirs on land-atmospheric feedbacks, have not yet been addressed. Regarding offline implications, we find that there are important elements, such as groundwater availability and withdrawals, and the representation of large reservoirs, which should be improved. Major sources of uncertainty in offline simulations include data support, water allocation algorithms and host large-scale models. Considering these findings with those highlighted in our companion paper, we note that advancements in computation, host models, system identification algorithms as well as remote sensing and data assimilation products can facilitate improved representations of water resource management at larger scales. We further propose a modular development framework to consider and test multiple datasets, algorithms and host models in a unified model diagnosis and uncertainty assessment framework. We suggest that such a framework is required to systematically improve current representations of water resource management in Earth System models. A key to this development is the availability of regional scale data. We argue that the time is right for a global initiative, based on regional case studies, to move this agenda forward.

  1. The role of ability, motivation, and opportunity to work in the transition from work to early retirement - testing and optimizing the Early Retirement Model

    NARCIS (Netherlands)

    de Wind, Astrid; Geuskens, Goedele A; Ybema, Jan Fekke; Bongers, Paulien M; van der Beek, Allard J

    2015-01-01

    OBJECTIVES: Determinants in the domains health, job characteristics, skills, and social and financial factors may influence early retirement through three central explanatory variables, namely, the ability, motivation, and opportunity to work. Based on the literature, we created the Early Retirement

  2. The role of ability, motivation, and opportunity to work in the transition from work to early retirement : testing and optimizing the Early Retirement Model

    NARCIS (Netherlands)

    Wind, A. de; Geuskens, G.A.; Ybema, J.F.; Bongers, P.M.; Beek, A.J. van der

    2015-01-01

    Objectives Determinants in the domains health, job characteristics, skills, and social and financial factors may influence early retirement through three central explanatory variables, namely, the ability, motivation, and opportunity to work. Based on the literature, we created the Early Retirement

  3. The role of ability, motivation, and opportunity to work in the transition from work to early retirement : testing and optimizing the Early Retirement Model

    NARCIS (Netherlands)

    Wind, A. de; Geuskens, G.A.; Ybema, J.F.; Bongers, P.M.; Beek, A.J. van der

    2015-01-01

    Objectives Determinants in the domains health, job characteristics, skills, and social and financial factors may influence early retirement through three central explanatory variables, namely, the ability, motivation, and opportunity to work. Based on the literature, we created the Early Retirement

  4. The role of ability, motivation, and opportunity to work in the transition from work to early retirement - testing and optimizing the Early Retirement Model

    NARCIS (Netherlands)

    de Wind, Astrid; Geuskens, Goedele A; Ybema, Jan Fekke; Bongers, Paulien M; van der Beek, Allard J

    2015-01-01

    OBJECTIVES: Determinants in the domains health, job characteristics, skills, and social and financial factors may influence early retirement through three central explanatory variables, namely, the ability, motivation, and opportunity to work. Based on the literature, we created the Early Retirement

  5. Environmental Modeling, The Natural Filter Buffer Targeting layers identify riparian forest and grass buffer opportunities by county. Land use and hydrology characteristics were used to identify potential riparian buffer locations., Published in 2014, Smaller than 1:100000 scale, Maryland Department of Natural Resources (DNR).

    Data.gov (United States)

    NSGIC Education | GIS Inventory — Environmental Modeling dataset current as of 2014. The Natural Filter Buffer Targeting layers identify riparian forest and grass buffer opportunities by county. Land...

  6. Opportunities with thermoplastics.

    Science.gov (United States)

    Vaahs, Tilo

    2003-04-01

    Whether as substitutes for glass and metal, or completely novel injection moulded applications, engineering polymers offer a range of opportunities for developing cost-effective, safe and smart medical devices.

  7. Seizing Political Opportunity

    DEFF Research Database (Denmark)

    Citi, Manuele; Justesen, Mogens Kamp

    2016-01-01

    Political actors need to be nimble and respond to the opportunity to reform old policies and initiate new ones. The article looks at how the European Commission takes advantage of politically opportune moments (the ‘gridlock interval’) in the European Parliament to put forward new legislation....... As a ‘policy entrepreneur’, it is therefore able to navigate European institutions and bring about change....

  8. Challenges and opportunities in advancing models of care for older adults: an assessment of the National Institute on Aging research portfolio.

    Science.gov (United States)

    Liggins, Charlene; Pryor, Lisa; Bernard, Marie A

    2010-12-01

    To identify existing projects supported by the National Institute on Aging (NIA) that may relate to the recommendations for models of care (MOCs) presented in the 2008 Institute of Medicine Report, Retooling for an Aging America: Building the Healthcare Workforce. Cross-sectional analysis of NIA's grant portfolio. NIA. NIA grantees. NIA's grant portfolio was queried for the period 1999 to 2008 using a variety of search terms related to MOCs. Inclusion criteria were adherence to guiding principles for MOCs (comprehensive care, efficient care, older person as an active partner) or focus on innovative feature(s) of MOCs (interdisciplinary care, care management, chronic disease self-management, pharmaceutical management, preventive home visits, proactive rehabilitation, transitional care). Exclusion criteria were lack of focus on an intervention and focus on informal caregivers. Expert NIA staff reviewed and validated projects. One hundred thirty-five grants were identified. These grants represent fewer than 1% of the approximate number of grants NIA has funded over this same period of time (∼24,000 grants). Forty-four percent focused on components of comprehensive care and 34% on active involvement of older adults. Approximately half specifically focused on innovative features of MOCs, ranging from chronic disease self-management (32%) and proactive rehabilitation (26%) to preventive home visits (1%) and transitional care (1%). The majority of projects were investigator-initiated grants (46%). NIA has supported the development of many interventions that include components of MOCs related to recommendations from the IOM report. The challenge for the future will be determining which of the many components of comprehensive care systems are most effective for which subsets of the elderly population and assessing opportunities for enhanced collaboration between public and private aging research stakeholders. © 2010, Copyright the Authors. Journal compilation © 2010

  9. Immigrant Capital and Entrepreneurial Opportunities

    Directory of Open Access Journals (Sweden)

    Malavika Sundararajan

    2016-01-01

    Full Text Available Objective: The main objective of this study is to define and operationalize the concept of immigrant capital, a key factor that differentiates immigrant from host country entrepreneurs in how they recognize and start new ventures. Research Design & Methods: A detailed analysis of contemporary immigrant entrepreneurship and opportunity recognition literature was carried out. Using grounded theory, we synthesized the outcomes from the analysis of eight Canadian and U.S. case studies of successful immigrant entrepreneurs with the key findings from the literature to define and develop a model of immigrant capital. Findings: Based on our grounded theory development process we show that the concept of immigrant capital as a distillate of human, cultural, economic and social capital that goes beyond expected opportunity recognition (OR drivers like prior knowledge and prior experience to differentiate and enhance the immigrant entrepreneur’s ability to recognize business opportunities compared to host country entrepreneurs. We found immigrant capital to be a consequence of being boundary spanners in host and home country networks. Implications & Recommendations: Understanding a unique resource like immigrant capital, will help immigrant as well as host country entrepreneurs further develop their opportunity recognition ability by bridging gaps and fulfilling the needs for both, immigrant and host country consumers. Contribution & Value Added: The main contribution is the theoretical development, identification and definition of the immigrant capital model and propositions that will articulate the factors that lead to the conceptualization and operationalization of immigrant capital. Furthermore, the immigrant capital model can serve host country entrepreneurs to develop cross-cultural networks and jump-start entrepreneurial activities in their home countries as well as learn how to expand their operations into global markets.

  10. Investment opportunities as real options

    Directory of Open Access Journals (Sweden)

    Adnan Rovčanin

    2005-06-01

    Full Text Available Opportunity (optional approach to capital investment appraisal represents, completely new theoretical and methodological framework for investment analysis. Compared to traditional, discount cash flow (DCF model of analysis, the optional approach provides opportunity for valuation and managing flexibility, i.e. possibility of approaching (amending the previous decisions in compliance with market changes. Risk and uncertainty are inevitably following the capital investment. Therefore, the importance of optional approach to investments is also that it provides possible better “treatment” of risks in the investment analysis, and also more rational allocation of resources, accordingly. This approach should be of more interest to the Countries in transition, considering the limited financial sources as well as risk and uncertainty are emphasized.

  11. Office of Equal Opportunity Programs

    Science.gov (United States)

    Chin, Jennifer L.

    2004-01-01

    The NASA Glenn Office of Equal Opportunity Programs works to provide quality service for all programs and/or to assist the Center in becoming a model workplace. During the summer of 2004, I worked with Deborah Cotleur along with other staff members to create and modify customer satisfaction surveys. This office aims to assist in developing a model workplace by providing functions as a change agent to the center by serving as an advisor to management to ensure equity throughout the Center. In addition, the office serves as a mediator for the Center in addressing issues and concerns. Lastly, the office provides assistance to employees to enable attainment of personal and organizational goals. The Office of Equal Opportunities is a staff office which reports and provides advice to the Center Director and Executive Leadership, implements laws, regulations, and presidential executive orders, and provides center wide leadership and assistance to NASA GRC employees. Some of the major responsibilities of the office include working with the discrimination complaints program, special emphasis programs (advisory groups), management support, monitoring and evaluation, contract compliance, and community outreach. During my internship in this office, my main objective was to create four customer satisfaction surveys based on EO retreats, EO observances, EO advisory boards, and EO mediation/counseling. I created these surveys after conducting research on past events and surveys as well as similar survey research created and conducted by other NASA centers, program for EO Advisory group members, leadership training sessions for supervisors, preventing sexual harassment training sessions, and observance events. I also conducted research on the style and format from feedback surveys from the Marshall Equal Opportunity website, the Goddard website, and the main NASA website. Using the material from the Office of Equal Opportunity Programs at Glenn Research Center along with my

  12. Office of Equal Opportunity Programs

    Science.gov (United States)

    Chin, Jennifer L.

    2004-01-01

    The NASA Glenn Office of Equal Opportunity Programs works to provide quality service for all programs and/or to assist the Center in becoming a model workplace. During the summer of 2004, I worked with Deborah Cotleur along with other staff members to create and modify customer satisfaction surveys. This office aims to assist in developing a model workplace by providing functions as a change agent to the center by serving as an advisor to management to ensure equity throughout the Center. In addition, the office serves as a mediator for the Center in addressing issues and concerns. Lastly, the office provides assistance to employees to enable attainment of personal and organizational goals. The Office of Equal Opportunities is a staff office which reports and provides advice to the Center Director and Executive Leadership, implements laws, regulations, and presidential executive orders, and provides center wide leadership and assistance to NASA GRC employees. Some of the major responsibilities of the office include working with the discrimination complaints program, special emphasis programs (advisory groups), management support, monitoring and evaluation, contract compliance, and community outreach. During my internship in this office, my main objective was to create four customer satisfaction surveys based on EO retreats, EO observances, EO advisory boards, and EO mediation/counseling. I created these surveys after conducting research on past events and surveys as well as similar survey research created and conducted by other NASA centers, program for EO Advisory group members, leadership training sessions for supervisors, preventing sexual harassment training sessions, and observance events. I also conducted research on the style and format from feedback surveys from the Marshall Equal Opportunity website, the Goddard website, and the main NASA website. Using the material from the Office of Equal Opportunity Programs at Glenn Research Center along with my

  13. Raiding Opportunities and Unemployment

    DEFF Research Database (Denmark)

    Tranæs, Torben

    2001-01-01

    This article studies the impact of raiding opportunities in a labor market in which worker abilities differ. Recruiting firms can either raid an elsewhere-employed worker of known ability by bidding up his wage or go through costly search to find a good worker among the unemployed. In equilibrium......, in particular, unemployment compensation, minimum wages, wage taxation, and search requirements.......This article studies the impact of raiding opportunities in a labor market in which worker abilities differ. Recruiting firms can either raid an elsewhere-employed worker of known ability by bidding up his wage or go through costly search to find a good worker among the unemployed. In equilibrium...

  14. PV opportunities in India

    Science.gov (United States)

    Stone, Jack L.; Ullal, Harin S.

    1996-01-01

    The growing middle class in India, coupled with a need for electricity to provide basic services to the masses, provides an opportunity to deploy photovoltaic systems in cost-effective applications ranging from grid-connected to isolated location requirements. This need is being satisfied by aggressive government programs, the availability of funds from agencies such as the World Bank, and the desire of Indian industries to form joint ventures for in-country manufacturing. The relaxed restrictions on doing business in India makes today's opportunities timely indeed.

  15. Opportunities for Biorenewables in Oil Refineries

    Energy Technology Data Exchange (ETDEWEB)

    Marker, T.L.

    2005-12-19

    Abstract: The purpose of this study was to evaluate the potential for using biorenewable feedstocks in oil refineries. Economic analyses were conducted, with support from process modeling and proof of principle experiments, to assess a variety of potential processes and configurations. The study considered two primary alternatives: the production of biodiesel and green diesel from vegetable oils and greases and opportunities for utilization of pyrolysis oil. The study identified a number of promising opportunities for biorenewables in existing or new refining operations.

  16. Land of Expat Opportunity

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    The international work force continues to grow as employment opportunities entice foreigners to live in China Forty-four-year-old Daniell Goodin has spent almost two decades working abroad, calling Indonesia, Hong Kong and the United States "home" for different periods of time. In May, the Australian native arrived in China, working

  17. Opportunity Cost: A Reply

    Science.gov (United States)

    Parkin, Michael

    2016-01-01

    The author's objective for this reply in reexamining opportunity cost was to draw attention to two conflicting definitions of the concept in current use and to argue the case for dropping one of them. The comments of Daniel Arce, Rod O'Donnell, and Daniel Stone might be read as demonstration that the author has failed on both counts. Such a…

  18. Expanding Student Assessment Opportunities.

    Science.gov (United States)

    Bartscher, Beth; Carter, Andrea; Lawlor, Anna; McKelvey, Barbara

    This paper describes an approach for expanding assessment opportunities for students to demonstrate their understanding of content. The targeted population consisted of elementary and junior high school students in two schools in a growing middle-class community in north central Illinois. The elementary school enrolled 467 students and the junior…

  19. Urbanization as opportunity

    OpenAIRE

    Fuller, Brandon; Romer, Paul

    2014-01-01

    Urbanization deserves urgent attention from policy makers, academics, entrepreneurs, and social reformers of all stripes. Nothing else will create as many opportunities for social and economic progress. The urbanization project began roughly 1,000 years after the transition from the Pleistocene to the milder and more stable Holocene interglacial. In 2010, the urban population in developing...

  20. Investment Insight Opportunities Ahead

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Over the next five years, China will be shitting its focus to more balanced development and what it sees as quality growth. Its two main strategies are promoting innovation-with the government-backed industrial upgrading-and strengthening the rural economy. This shift will lead to massive investment and fresh, wealth-making opportunities. In the stock

  1. The Educational Opportunity Bank.

    Science.gov (United States)

    Jellema, William W.

    The Educational Opportunity Bank (EOB) has received short shrift among educators and many objections have been raised to establishing it. Among these are the workability of the plan, the problem for women borrowers, and the creation of a new force--student financial power - in opposition to the influence of the Federal Government. Though…

  2. User Frustrations as Opportunities

    Directory of Open Access Journals (Sweden)

    Michael Weiss

    2012-04-01

    Full Text Available User frustrations are an excellent source of new product ideas. Starting with this observation, this article describes an approach that entrepreneurs can use to discover business opportunities. Opportunity discovery starts with a problem that the user has, but may not be able to articulate. User-centered design techniques can help elicit those latent needs. The entrepreneur should then try to understand how users are solving their problem today, before proposing a solution that draws on the unique skills and technical capabilities available to the entrepreneur. Finally, an in-depth understanding of the user allows the entrepreneur to hone in on the points of difference and resonance that are the foundation of a strong customer value proposition.

  3. Project X: Physics Opportunities

    CERN Document Server

    Kronfeld, Andreas S; Al-Binni, Usama; Altmannshofer, Wolfgang; Ankenbrandt, Charles; Babu, Kaladi; Banerjee, Sunanda; Bass, Matthew; Batell, Brian; Baxter, David V; Berezhiani, Zurab; Bergevin, Marc; Bernstein, Robert; Bhattacharya, Sudeb; Bishai, Mary; Blum, Thomas; Bogacz, S Alex; Brice, Stephen J; Brod, Joachim; Bross, Alan; Buchoff, Michael; Burgess, Thomas W; Carena, Marcela; Castellanos, Luis A; Chattopadhyay, Subhasis; Chen, Mu-Chun; Cherdack, Daniel; Christ, Norman H; Chupp, Tim; Cirigliano, Vincenzo; Coloma, Pilar; Coppola, Christopher E; Cowsik, Ramanath; Crabtree, J Allen; Delahaye, Jean-Pierre; Denisov, Dmitri; deNiverville, Patrick; de Gouvêa, André; Dharmapalan, Ranjan; Dolgov, Alexander; Dvali, Georgi; Eichten, Estia; Engelfried, Jürgen; Ferguson, Phillip D; Gabriel, Tony; Gal, Avraham; Gallmeier, Franz; Ganezer, Kenneth S; Gardner, Susan; Glenzinski, Douglas; Godfrey, Stephen; Golubeva, Elena S; Gori, Stefania; Graves, Van B; Greene, Geoffrey; Griffard, Cory L; Haisch, Ulrich; Handler, Thomas; Hartfiel, Brandon; Hawari, Ayman; Heilbronn, Lawrence; Hill, James E; Huber, Patrick; Jaffe, David E; Johnson, Christian; Kamyshkov, Yuri; Kaplan, Daniel M; Kerbikov, Boris; Kiburg, Brendan; Kirk, Harold G; Klein, Andreas; Knoepfel, Kyle; Kopeliovich, Boris; Kopeliovich, Vladimir; Kopp, Joachim; Korsch, Wolfgang; Kribs, Graham; Lipton, Ronald; Liu, Chen-Yu; Lorenzon, Wolfgang; Lu, Zheng-Tian; Makins, Naomi C R; McKeen, David; Mills, Geoffrey; Mohapatra, Rabindra; Mokhov, Nikolai V; Mocko, Michael; Muhrer, Guenter; Mumm, Pieter; Okun, Lev; Neuffer, David; Palmer, Mark A; Palmer, Robert; Pattie, Robert W; Phillips, David G; Pronsikh, Vitaly; Pitts, Kevin; Pospelov, Maxim; Quigg, Chris; Ramberg, Erik; Ray, Amlan; Reimer, Paul E; Richards, David G; Ritz, Adam; Roy, Amit; Ruggles, Arthur; Ryne, Robert; Sarkar, Utpal; Saunders, Andy; Semertzidis, Yannis K; Serebrov, Anatoly; Shimizu, Hirohiko; Shrock, Robert; Snopok, Pavel V; Snow, William M; Sikdar, Arindam K; Soha, Aria; Spanier, Stefan; Striganov, Sergei; Tang, Zhaowen; Townsend, Lawrence; Urheim, Jon; Vainshtein, Arkady; Van Kooten, Richard J; Van de Water, Richard; Van de Water, Ruth S; Wehring, Bernard; Whitehead, Lisa; Wilson, Robert J; Worcester, Elizabeth; Young, Albert R; Wester, William C; Zeller, Geralyn

    2013-01-01

    Part 2 of "Project X: Accelerator Reference Design, Physics Opportunities, Broader Impacts". In this Part, we outline the particle-physics program that can be achieved with Project X, a staged superconducting linac for intensity-frontier particle physics. Topics include neutrino physics, kaon physics, muon physics, electric dipole moments, neutron-antineutron oscillations, new light particles, hadron structure, hadron spectroscopy, and lattice-QCD calculations.

  4. Nanoethics: Challenges and Opportunities

    Science.gov (United States)

    Pompidou, Alain; Pompidou, Alain; Pompidou, Alain; Pompidou, Alain

    Nanoscience and its technological consequences constitute a relatively recent field of knowledge. Their rapid development around the world is characterised by an absence of specific norms and standards. Industrial applications, already promising, are not without risk, and this risk deserves to be fully and rigorously assessed. On the other hand, this vigilance and anticipation of risk does not need to deprive society as a whole of new opportunities, whether they be for developed countries and the emerging economies, or for less developed nations.

  5. Equal Opportunities Advisory Panel

    CERN Multimedia

    HR Department

    2006-01-01

    At its meeting on 7 December 2006, the Standing Concertation Committee took note of the appointment of four new members of the Panel: Wisla Carena, Pierre Charrue, Sue Foffano and Markus Nordberg. The present composition of the Panel (appointed ad personam) is as follows: Tiziano Camporesi (Chairperson), Wisla Carena, Pierre Charrue, Sue Foffano, Josi Schinzel (Equal Opportunities Officer), Markus Nordberg, Christine Petit-Jean-Genaz et Elena Wildner. Human Resources Department Tel. 74480

  6. Concurrent sourcing and external supplier opportunism

    DEFF Research Database (Denmark)

    Mols, Niels Peter

    When a firm simultaneously makes and buys the same components then the firm uses concurrent sourcing. This paper presents an agency model for explaining how and when concurrent sourcing reduces the likelihood of external supplier opportunism. In the proposed model, the external supplier’s expected...

  7. Opportunities for pharmacy.

    Science.gov (United States)

    Schneider, Philip J

    2007-07-15

    To summarize key points from the most recent Institute of Medicine (IOM) report, Preventing Medication Errors, and their relevance to health-system pharmacists. Creating a culture of safety is an important antecedent to making changes needed to reduce medication errors. The patient can play an important, but often unrealized, role in preventing medication errors. There are considerable opportunities to improve the application of technology to prevent medication errors. The National Hospital Pharmacy surveys conducted ty the American Society of Health- System Pharmacists have demonstrated the slow rate of adoption of technologies. Pharmacists can play a leadership role in improving both the patients' role and the use of technology to improve medication-use safety. There are major opportunities for pharmacists to re-think how involved patients are in their care in the institutional setting, by seeing patients as building another check into the medication-use system and by recommitting ourselves to getting patients involved. There are also opportunities to help with patient-safety technology decisions. These extremely expensive technologies almost always involve people changing what they do and their implementation and use often involve other people besides pharmacists, yet the potential is great for new technologies to reduce medication errors.

  8. Ethical Perspectives of Equal Opportunities

    Directory of Open Access Journals (Sweden)

    Traian PALADE

    2016-07-01

    Full Text Available This paper focuses on the analysis of the fair equality of the concept of opportunity from the perspective of the moral and reasonable justifications brought to support positive discrimination. Although contemporary democratic societies guarantee the absence of discrimination by securing the formal equality of opportunity, this seems to be insufficient to balance opportunities. The Rawlsian model has gained ground, by advancing a redistribution of the resources to support the disadvantaged ones, which is implemented through special measures. The compulsory quotas for admission to higher education or public institutions, addressed to some disadvantaged groups, are one of the effective means of implementing fairness. As this system has shattered the principle of reward judging by one‟s merits, and ending up as a form of inverse discrimination of the majority groups, it is necessary that we analyse the arguments and the boomerang effects of the special measures. The undertaking proposed by the present paper is structured around highlighting the ethical aspects, as well as the consequences resulting from the arguments in favour of positive discrimination. Do we have the moral obligation to make up for the past inequalities suffered by some groups? Does preferential treatment really ensure the genuine integration of such groups? Do special measures contribute in creating social justice? Without the claim of having responded definitively and exhaustively to these questions, this paper attempts to emphasise the ethical dilemma that raises when special measures favour one group or another, when a group is protected judging by only one criterion, or when only an implementation area is selected.

  9. Funding Opportunity: Genomic Data Centers

    Science.gov (United States)

    Funding Opportunity CCG, Funding Opportunity Center for Cancer Genomics, CCG, Center for Cancer Genomics, CCG RFA, Center for cancer genomics rfa, genomic data analysis network, genomic data analysis network centers,

  10. Informal Opportunity among SMEs

    DEFF Research Database (Denmark)

    Rezaei, Shahamak; Dana, Leo-Paul; Goli, Marco

    2013-01-01

    Based on interviews with (legal and illegal) immigrants to Denmark, meetings with stakeholders and with experts in the field, this article addresses issues regarding the underground economy. Our findings show that, in Denmark, the existence of an underground economy makes it possible for semi......-compliant and non-compliant immigrants to make a living. We suggest that the underground economy in Denmark will continue to provide networks of illegal residents with opportunities for informal economic activities as trust allows entrepreneurs to function below the radar, by owning enterprises registered using...

  11. Frontier Aerospace Opportunities

    Science.gov (United States)

    Bushnell, Dennis M.

    2014-01-01

    Discussion and suggested applications of the many ongoing technology opportunities for aerospace products and missions, resulting in often revolutionary capabilities. The, at this point largely unexamined, plethora of possibilities going forward, a subset of which is discussed, could literally reinvent aerospace but requires triage of many possibilities. Such initial upfront homework would lengthen the Research and Development (R&D) time frame but could greatly enhance the affordability and performance of the evolved products and capabilities. Structural nanotubes and exotic energetics along with some unique systems approaches are particularly compelling.

  12. Nanotechnology: Opportunities and Challenges

    Science.gov (United States)

    Meyyappan, Meyya

    2003-01-01

    Nanotechnology seeks to exploit novel physical, chemical, biological, mechanical, electrical, and other properties, which arise primarily due to the nanoscale nature of certain materials. A key example is carbon nanotubes (CNTs) which exhibit unique electrical and extraordinary mechanical properties and offer remarkable potential for revolutionary applications in electronics devices, computing, and data storage technology, sensors, composites, nanoelectromechanical systems (NEMS), and as tip in scanning probe microscopy (SPM) for imaging and nanolithography. Thus the CNT synthesis, characterization, and applications touch upon all disciplines of science and engineering. This presentation will provide an overview and progress report on this and other major research candidates in Nanotechnology and address opportunities and challenges ahead.

  13. Creating Innovative Opportunities

    DEFF Research Database (Denmark)

    Ljungberg, Daniel; McKelvey, Maureen; Lassen, Astrid Heidemann

    2012-01-01

    to illustrations of the processes, and the 86 case studies in knowledge intensive entrepreneurship in Europe. These case studies were developed during the European Union research project AEGIS (Advancing Knowledge-Intensive Entrepreneurship and Innovation for Economic Growth and Well-being in Europe). The case...... studies do demonstrate how the individual KIE ventures are dependent upon variables and processes in the surrounding innovation systems. The overall analysis of the cases provides insight into how KIE processes link the KIE venture and the innovation system, thereby highlighting e.g. the importance...... of knowledge networks to create innovative opportunities....

  14. Multiphysics simulations: challenges and opportunities.

    Energy Technology Data Exchange (ETDEWEB)

    Keyes, D.; McInnes, L. C.; Woodward, C.; Gropp, W.; Myra, E.; Pernice, M. (Mathematics and Computer Science); (KAUST and Columbia Univ.); (Lawrence Livermore National Laboratory); (Univ. of Illinois at Urbana-Champaign); (Univ. of Mich.); (Idaho National Lab.)

    2012-11-29

    This report is an outcome of the workshop Multiphysics Simulations: Challenges and Opportunities, sponsored by the Institute of Computing in Science (ICiS). Additional information about the workshop, including relevant reading and presentations on multiphysics issues in applications, algorithms, and software, is available via https://sites.google.com/site/icismultiphysics2011/. We consider multiphysics applications from algorithmic and architectural perspectives, where 'algorithmic' includes both mathematical analysis and computational complexity and 'architectural' includes both software and hardware environments. Many diverse multiphysics applications can be reduced, en route to their computational simulation, to a common algebraic coupling paradigm. Mathematical analysis of multiphysics coupling in this form is not always practical for realistic applications, but model problems representative of applications discussed herein can provide insight. A variety of software frameworks for multiphysics applications have been constructed and refined within disciplinary communities and executed on leading-edge computer systems. We examine several of these, expose some commonalities among them, and attempt to extrapolate best practices to future systems. From our study, we summarize challenges and forecast opportunities. We also initiate a modest suite of test problems encompassing features present in many applications.

  15. Opportunity and obligation

    CERN Document Server

    2012-01-01

    As anyone in the press or VIP offices can tell you, CERN is in the spotlight like never before. In the first two months of 2012, we welcomed some 56 VIP visits and 144 media visits on site. Not long ago, those were the kind of numbers we’d have had in six months, and 2012 is not a one-off.   Ever since CERN turned 50 in 2004, our visitor numbers have been growing, and that includes teachers and members of the public as well as VIPs and the media. It’s a sign of the explosion of interest around the world in our science, and to me it means two things. Firstly, it means that I owe everyone at CERN a vote of thanks, since I know that visits impinge on everyone’s time. I can assure you all, however, that it is time well spent. That’s because the second thing it tells me is that growing interest in CERN brings opportunity. Our current visibility gives the particle physics community the opportunity to drive science up the popular and political agendas, and it...

  16. Multiphysics Simulations: Challenges and Opportunities

    Energy Technology Data Exchange (ETDEWEB)

    Keyes, David; McInnes, Lois C.; Woodward, Carol; Gropp, William; Myra, Eric; Pernice, Michael; Bell, John; Brown, Jed; Clo, Alain; Connors, Jeffrey; Constantinescu, Emil; Estep, Don; Evans, Kate; Farhat, Charbel; Hakim, Ammar; Hammond, Glenn E.; Hansen, Glen; Hill, Judith; Isaac, Tobin; Jiao, Xiangmin; Jordan, Kirk; Kaushik, Dinesh; Kaxiras, Efthimios; Koniges, Alice; Lee, Ki Hwan; Lott, Aaron; Lu, Qiming; Magerlein, John; Maxwell, Reed M.; McCourt, Michael; Mehl, Miriam; Pawlowski, Roger; Randles, Amanda; Reynolds, Daniel; Riviere, Beatrice; Rude, Ulrich; Scheibe, Timothy D.; Shadid, John; Sheehan, Brendan; Shephard, Mark; Siegel, Andrew; Smith, Barry; Tang, Xianzhu; Wilson, Cian; Wohlmuth, Barbara

    2013-02-12

    We consider multiphysics applications from algorithmic and architectural perspectives, where ‘‘algorithmic’’ includes both mathematical analysis and computational complexity, and ‘‘architectural’’ includes both software and hardware environments. Many diverse multiphysics applications can be reduced, en route to their computational simulation, to a common algebraic coupling paradigm. Mathematical analysis of multiphysics coupling in this form is not always practical for realistic applications, but model problems representative of applications discussed herein can provide insight. A variety of software frameworks for multiphysics applications have been constructed and refined within disciplinary communities and executed on leading-edge computer systems. We examine several of these, expose some commonalities among them, and attempt to extrapolate best practices to future systems. From our study, we summarize challenges and forecast opportunities.

  17. Multiphysics simulations: Challenges and opportunities

    KAUST Repository

    Keyes, David E.

    2013-02-01

    We consider multiphysics applications from algorithmic and architectural perspectives, where "algorithmic" includes both mathematical analysis and computational complexity, and "architectural" includes both software and hardware environments. Many diverse multiphysics applications can be reduced, en route to their computational simulation, to a common algebraic coupling paradigm. Mathematical analysis of multiphysics coupling in this form is not always practical for realistic applications, but model problems representative of applications discussed herein can provide insight. A variety of software frameworks for multiphysics applications have been constructed and refined within disciplinary communities and executed on leading-edge computer systems. We examine several of these, expose some commonalities among them, and attempt to extrapolate best practices to future systems. From our study, we summarize challenges and forecast opportunities. © The Author(s) 2012.

  18. Opportunities within ASTERICS

    Science.gov (United States)

    van der Meer, Rob; Cimò, Giuseppe

    2016-04-01

    ASTERICS, The Astronomy ESFRI and Research Infrastructure Cluster project, brings together astronomers and astroparticle physicists of 22 institutes in Europe to help Europe's world-leading observatories work together to find common solutions to their Big Data challenges, their interoperability and scheduling, and their data access, searching for cross-cutting solutions with mutual and wide-ranging benefit to all concerned. ASTERICS is a four year project, funded through the European Union's Horizon 2020 Framework Programme. The facilities supported by ASTERICS include SKA, CTA, KM3NeT, E-ELT. ASTERICS aims to open up multi messenger astronomy to all scientists and the public through the Virtual Observatory and the citizen science work. I will draw a picture of the landscape in which ASTERICS operates and the possible interaction with the Very Large Volume Neutrino Telescope community. Attention will be given to emerging opportunities for the Neutrino community and how these can be recognised or created.

  19. Generating innovation opportunities:

    DEFF Research Database (Denmark)

    Kallio, Anne; Bergenholtz, Carsten

    2011-01-01

    This study examines how a company can generate innovation opportunities by exploring and absorbing customer knowledge. The exploration can be performed via an in-depth or broad search for resources beyond organisational boundaries. Salespeople are an essential channel for an in-depth search...... in relation to customers, since salespeople possess rich knowledge of the customers. In order to be useful, such knowledge has to be absorbed in the company. Most of the literature on absorptive capacity has focused on R&D, while less focus has been placed on studying the role of individuals...... in the development of integrative practices. This paper demonstrates how a community of practice can enable organisations to move from potential absorptive capacity to realised absorptive capacity....

  20. Teleradiology: threat or opportunity?

    Energy Technology Data Exchange (ETDEWEB)

    Jarvis, L. [Medical Operations Division, Fleet Headquarters, Porstmouth (United Kingdom)]. E-mail: lioneljarvis@aol.com; Stanberry, B. [Avienda Limited, Cardiff, Wales (United Kingdom)

    2005-08-01

    The rapid advances in information technology and communication bandwidth have spawned an equally rapid development of clinical teleradiology. Current computer technology and communication capability allow easy transfer of diagnostic images, of any complexity, to any location in the world. This provides the opportunity to acquire swift primary and secondary diagnostic opinions from the remotest of locations, often at economically attractive rates, with the potential for easing the burden on hard-pressed departments of radiology. However, this comes at the potential cost of distancing the clinical radiologist from the patient, with consequent impact upon direct clinical care. As this technology advances across the world, it is vital that UK radiologists are familiar with the clinical implications, the medicolegal framework within which the field operates and the associated governance issues. This paper reviews current practice and discusses the associated risks.

  1. Evolutionary constraints or opportunities?

    Science.gov (United States)

    Sharov, Alexei A.

    2014-01-01

    Natural selection is traditionally viewed as a leading factor of evolution, whereas variation is assumed to be random and non-directional. Any order in variation is attributed to epigenetic or developmental constraints that can hinder the action of natural selection. In contrast I consider the positive role of epigenetic mechanisms in evolution because they provide organisms with opportunities for rapid adaptive change. Because the term “constraint” has negative connotations, I use the term “regulated variation” to emphasize the adaptive nature of phenotypic variation, which helps populations and species to survive and evolve in changing environments. The capacity to produce regulated variation is a phenotypic property, which is not described in the genome. Instead, the genome acts as a switchboard, where mostly random mutations switch “on” or “off” preexisting functional capacities of organism components. Thus, there are two channels of heredity: informational (genomic) and structure-functional (phenotypic). Functional capacities of organisms most likely emerged in a chain of modifications and combinations of more simple ancestral functions. The role of DNA has been to keep records of these changes (without describing the result) so that they can be reproduced in the following generations. Evolutionary opportunities include adjustments of individual functions, multitasking, connection between various components of an organism, and interaction between organisms. The adaptive nature of regulated variation can be explained by the differential success of lineages in macro-evolution. Lineages with more advantageous patterns of regulated variation are likely to produce more species and secure more resources (i.e., long-term lineage selection). PMID:24769155

  2. Linguistic Opportunism and English in Moldova.

    Science.gov (United States)

    Ciscel, Matthew H.

    2002-01-01

    Investigates the role of English in Moldova. Building on Phillipson's concept of linguistic imperialism and Kachru's three concentric circles of world Englishes, proposes a weak form of linguistic dominance based on the notion of opportunism. The model is supported by data from a recent study of language attitudes and language use in Moldova. Data…

  3. Learning Opportunities (Editorial

    Directory of Open Access Journals (Sweden)

    Denise Koufogiannakis

    2009-12-01

    Full Text Available We’ve reached the end of another year of publication at EBLIP, my first at the helm as Editor‐in‐Chief, and four full years of publication since we began. This year was a busy one with several changes to the editorial team, the addition of more Editorial Advisors, and new evidence summary writers joining our team. Most importantly, the journal continues to grow and thrive, with more people than ever participating in its success. This year we added a new section called Using Evidence in Practice, and in this issue there are two articles in that section which provide practical examples of applying evidence in the workplace. Putting evidence into practice is what EBLIP is all about, so it is my hope that this new section makes the application of evidence based practice more concrete for readers. As we began working on issue 4.4, the Editorial Team decided that it would be a good idea to seek out an Editorial Intern to help with some of the tasks we never seem to get to, given that we are all volunteers. We see the internship as an opportunity to give a library and information studies student a chance to get involved with an open access journal and learn about publishing in library and information studies, which will hopefully benefit them as they begin their new career. The Editorial Intern will assist with marketing and promotion of the journal, soliciting potential manuscripts, and proofreading. They will also participate in all editorial meetings and general discussions. We anticipate that they will bring a wealth of enthusiasm and fresh ideas to our conversations so that EBLIP Editors can also continue to learn and grow by having a fresh set of eyes involved with our processes. It will certainly be a win‐win situation and a learning opportunity for all involved. We are pleased to announce that Andrea Baer has accepted the position of Editorial Intern and joined our team in mid‐November. Andrea is currently attending the University of

  4. Climate Change Creates Trade Opportunity in India

    OpenAIRE

    Dinda, Soumyananda

    2013-01-01

    Climate change is an emerging challenge to developing economy like India however it also creates opportunity to grow through climate friendly goods production and new direction of trade. This paper focuses India’s potential export trade in climate friendly goods. The estimated gravity model is defined as the potential trade and potential trade gap is measured as how well a bilateral trade flow performs relative to the mean as predicted by the model. Potential trade gap means that actual trade...

  5. Arc of opportunity.

    Science.gov (United States)

    Delaney, Adam Vai

    2011-07-01

    Born in Port Moresby, Papua New Guinea, the author had a 20 year career in diplomacy, political affairs, and development policy analysis at the Pacific Islands Forum, the United Nations in New York; the Prime Minister's Department in Papua New Guinea (PNG) and in the Foreign Ministry of PNG. He has also been involved in theatre for over a decade in PNG, and participated in a three-month program at the Eugene O'Neill Theatre Center in Connecticut, USA. He is currently the Business Development Manager at the Torres Strait Regional Authority (Commonwealth) on Thursday Island. Since 1975 the Australian government's overseas development policy has supported various sectoral programs in its neighbouring countries, in particular Papua New Guinea and the Solomon Islands. The "creative" field has not been prominent in this strategy. While natural resources and the sports sectors have gained much greater attention, in terms of being viable international commercial enterprises, the arts, have remained stagnant. In this paper the need for joint programs genuinely supporting "wellbeing" and promoting social enterprise throughout the "arc of opportunity" is described to harness Melanesian creativity to compete successfully in world-markets, starting with penetration of the largest economy at its door-step: Australia.

  6. Plastics recycling: challenges and opportunities

    National Research Council Canada - National Science Library

    Jefferson Hopewell; Robert Dvorak; Edward Kosior

    2009-01-01

    .... Advances in technologies and systems for the collection, sorting and reprocessing of recyclable plastics are creating new opportunities for recycling, and with the combined actions of the public...

  7. Report on Integration of Existing Grid Models for N-R HES Interaction Focused on Balancing Authorities for Sub-hour Penalties and Opportunities

    Energy Technology Data Exchange (ETDEWEB)

    McJunkin, Timothy; Epiney, Aaron; Rabiti, Cristian

    2017-06-01

    This report provides a summary of the effort in the Nuclear-Renewable Hybrid Energy System (N-R HES) project on the level 4 milestone to consider integration of existing grid models into the factors for optimization on shorter time intervals than the existing electric grid models with the Risk Analysis Virtual Environment (RAVEN) and Modelica [1] optimizations and economic analysis that are the focus of the project to date.

  8. ADVANCES IN DECISION ANALYSIS AND SYSTEMS ENGINEERING FOR MANAGING LARGE-SCALE ENTERPRISES IN A VOLATILE WORLD: INTEGRATING BENEFITS, OPPORTUNITIES, COSTS AND RISKS (BOCR) WITH THE BUSINESS MOTIVATION MODEL (BMM)

    Institute of Scientific and Technical Information of China (English)

    Tom FEGLAR; Jason K.LEVY; Tatiana FEGLAR; Tomas FEGLAR,JR.

    2006-01-01

    Over the past few decades, innovations in Information and Communication Technologies (ICT)have led to a significant increase in the complexity of enterprise information systems. This has led to new challenges for enterprise architects, systems engineers, business managers and other decision makers who must cope with the complexity of business plans and processes (particularly automated engineering processes). In order to better manage this complexity, the Business Rule Group (BRG) has put forth the Business Motivation Model (BMM). The original BMM uses a SWOT (Strength,Weakness, Opportunity, and Threat) decision analysis approach. However, the SWOT framework contains significant limitations with respect to decision making and ICT risks, hampering the decision making ability of enterprise architects, business managers, engineers, and other decision makers. The AHP (Analytic Hierarchy Process) and ANP (Analytic Network Process) are among the most widely used decision making tools: they commonly implement a Benefit - Opportunity - Cost - Risk (BOCR)analysis to improve the effectiveness of business decision making. A new approach is put forth that replaces the original SWOT assessment with an ANP-based BOCR analysis. As well, the original BMM is modified and applied in a Component Architecture Framework (CAF).

  9. DIGITAL PAKISTAN: OPPORTUNITIES & CHALLENGES

    Directory of Open Access Journals (Sweden)

    Ghulam Muhammad Kundi

    2008-10-01

    Full Text Available IT has revolutionized the social and organizational life around the globe. Given the newness of IT as a technology, there is a lot of potential that needs to be explored. It is however, argued that as IT can revolutionize the economic development, by the same coin, although its mismanagement in adoption process can end up in problems or even straight failure of the technology at the business-end. This study was conducted with reference to opportunities and challenges in the IT adoption process in Pakistan. The aim of the study was to point out the barriers that are impeding the country’s computerization process in order to provide facts to the policy makers for smooth computerization. The primary data collected through structured questionnaires was analyzed and tested through correlation, regressions analysis and t-test. Out of 10 hypotheses, 3 were accepted while in the rest null hypotheses were not substantiated. Based on primary and secondary data analysis this study has found that all independent bureaucratic, political, education and social and cultural variables are mutually correlated and have significant impact on shaping and reshaping of IT in Pakistan, while the Pakistan IT policy is inconsistent, administrative machinery attitude is negative and non cooperative, procedures are cumbersome and implementation is weak and ineffective, not to mention the lack of IT knowledge on the bureaucratic side. The political environment is instable and law and order is worse which is discouraging the investment. Moreover, physical and legal infrastructure is insufficient and the country is lacking good quality IT professionals. IT organization alignment is another serious issue in Pakistan. However, government incentives and growing interest from the private sector indicate positive attitude towards computerization of the country.

  10. DIGITAL PAKISTAN: OPPORTUNITIES & CHALLENGES

    Directory of Open Access Journals (Sweden)

    Ghulam Muhammad Kundi

    2008-12-01

    Full Text Available ABSTRACT IT has revolutionized the social and organizational life around the globe. Given the newness of IT as a technology, there is a lot of potential that needs to be explored. It is however, argued that as IT can revolutionize the economic development, by the same coin, although its mismanagement in adoption process can end up in problems or even straight failure of the technology at the business-end. This study was conducted with reference to opportunities and challenges in the IT adoption process in Pakistan. The aim of the study was to point out the barriers that are impeding the country’s computerization process in order to provide facts to the policy makers for smooth computerization. The primary data collected through structured questionnaires was analyzed and tested through correlation, regressions analysis and t-test. Out of 10 hypotheses, 3 were accepted while in the rest null hypotheses were not substantiated. Based on primary and secondary data analysis this study has found that all independent bureaucratic, political, education and social and cultural variables are mutually correlated and have significant impact on shaping and reshaping of IT in Pakistan, while the Pakistan IT policy is inconsistent, administrative machinery attitude is negative and non cooperative, procedures are cumbersome and implementation is weak and ineffective, not to mention the lack of IT knowledge on the bureaucratic side. The political environment is instable and law and order is worse which is discouraging the investment. Moreover, physical and legal infrastructure is insufficient and the country is lacking good quality IT professionals. IT organization alignment is another serious issue in Pakistan. However, government incentives and growing interest from the private sector indicate positive attitude towards computerization of the country.

  11. Barriers and opportunities for evidence-based health service planning: the example of developing a Decision Analytic Model to plan services for sexually transmitted infections in the UK

    Directory of Open Access Journals (Sweden)

    Aicken Catherine R H

    2012-07-01

    Full Text Available Abstract Background Decision Analytic Models (DAMs are established means of evidence-synthesis to differentiate between health interventions. They have mainly been used to inform clinical decisions and health technology assessment at the national level, yet could also inform local health service planning. For this, a DAM must take into account the needs of the local population, but also the needs of those planning its services. Drawing on our experiences from stakeholder consultations, where we presented the potential utility of a DAM for planning local health services for sexually transmitted infections (STIs in the UK, and the evidence it could use to inform decisions regarding different combinations of service provision, in terms of their costs, cost-effectiveness, and public health outcomes, we discuss the barriers perceived by stakeholders to the use of DAMs to inform service planning for local populations, including (1 a tension between individual and population perspectives; (2 reductionism; and (3 a lack of transparency regarding models, their assumptions, and the motivations of those generating models. Discussion Technological advances, including improvements in computing capability, are facilitating the development and use of models such as DAMs for health service planning. However, given the current scepticism among many stakeholders, encouraging informed critique and promoting trust in models to aid health service planning is vital, for example by making available and explicit the methods and assumptions underlying each model, associated limitations, and the process of validation. This can be achieved by consultation and training with the intended users, and by allowing access to the workings of the models, and their underlying assumptions (e.g. via the internet, to show how they actually work. Summary Constructive discussion and education will help build a consensus on the purposes of STI services, the need for service planning to

  12. Opportunity Loss Minimization and Newsvendor Behavior

    Directory of Open Access Journals (Sweden)

    Xinsheng Xu

    2017-01-01

    Full Text Available To study the decision bias in newsvendor behavior, this paper introduces an opportunity loss minimization criterion into the newsvendor model with backordering. We apply the Conditional Value-at-Risk (CVaR measure to hedge against the potential risks from newsvendor’s order decision. We obtain the optimal order quantities for a newsvendor to minimize the expected opportunity loss and CVaR of opportunity loss. It is proven that the newsvendor’s optimal order quantity is related to the density function of market demand when the newsvendor exhibits risk-averse preference, which is inconsistent with the results in Schweitzer and Cachon (2000. The numerical example shows that the optimal order quantity that minimizes CVaR of opportunity loss is bigger than expected profit maximization (EPM order quantity for high-profit products and smaller than EPM order quantity for low-profit products, which is different from the experimental results in Schweitzer and Cachon (2000. A sensitivity analysis of changing the operation parameters of the two optimal order quantities is discussed. Our results confirm that high return implies high risk, while low risk comes with low return. Based on the results, some managerial insights are suggested for the risk management of the newsvendor model with backordering.

  13. OPPORTUNITIES OF PEDAGOGICAL MODELING IN THE SOLVING OF THE PROBLEM OF THE FORMATION OF THE DESIGN AND RESEARCH COMPETENCE OF HIGH SCHOOL STUDENTS

    Directory of Open Access Journals (Sweden)

    Инга Валерьевна Дементьева

    2013-12-01

    Full Text Available The problem of  forming high-school students’  design and research  competence can be successfully solved with the help of the realization of pedagogical model based on the systematic, person- orientated  and competence - active  approach. The aim of the research is to theoretically justify and experimentally  examine  the model of formation  of high-school students’ design and research competence.  The importance of the research is that during it the set of scientific approaches (systematic, person- orientated  and competence - active  ones as the methodological basis for projecting the model were justified and the complex of pedagogical conditions served as the guide for the further research of the problem of  high-school students’  design and research  competence formation. The methods of the analysis of pedagogical, methodological literature, theoretical modeling, as well as empiric methods of research served as the basis of the methodology of the research in the process of model approbation.   The value of  the given research is that the practice-oriented model of forming design and research competence of high school students represents the multilevel dynamic system consisting of mutually conditioned components (objective, methodological, meaningful, technological and diagnostic-effective ones and can be included into the practice of other educational institutions.DOI: http://dx.doi.org/10.12731/2218-7405-2013-11-2

  14. Research Handbook on Entrepreneurial Opportunities

    DEFF Research Database (Denmark)

    With a wide-ranging set of contributions, this book provides a compilation of cutting-edge original research in the field of entrepreneurial opportunities. The book reopens the subject from diverse perspectives focusing on theories and approaches to entrepreneurial opportunities. The book has bee...

  15. Oilseeds business opportunities in Ethiopia

    NARCIS (Netherlands)

    Wijnands, J.H.M.; Biersteker, J.; Hiel, R.

    2007-01-01

    In this study the business opportunities for Dutch companies in the Ethiopian oilseeds sector are explored. Opportunities for setting up sustainable export chains should mutually benefit Dutch companies as well as the Ethiopian oilseeds sector in particular and the Ethiopian society in general.

  16. Adult Learning Opportunities in Nepal

    Science.gov (United States)

    Regmi, Krishna; Regmi, Sharada

    2008-01-01

    This paper presents the initial findings from a study of education system in Nepal. This paper examines the adult learning opportunities within the educational and cultural contexts by reviewing available literature relevant to Nepal. Findings show that there are wider opportunities for adult learning than those considered from education and…

  17. APPLICATION OF A MODEL OF ASSESSMENT FOR DETECTION OF FOOD WASTE IN SCHOOL CANTEENS: AN OPPORTUNITY TO MONITOR SEVERAL FOOD RISK FACTORS

    Directory of Open Access Journals (Sweden)

    S. Saccares

    2012-08-01

    Full Text Available Application of a model for detection of food waste, applied within a school canteen, allows to make different assessments on critical points encountered in the service. The detection system can complete the HACCP path and provide useful guidance for official control Services, involved in food safety.

  18. Operational modelling to guide implementation and scale-up of diagnostic tests within the health system: exploring opportunities for parasitic disease diagnostics based on example application for tuberculosis.

    Science.gov (United States)

    Langley, Ivor; Adams, Emily; Doulla, Basra; Squire, S Bertel

    2014-12-01

    Research and innovation in the diagnosis of infectious and parasitic diseases has led to the development of several promising diagnostic tools, for example in malaria there is extensive literature concerning the use of rapid diagnostic tests. This means policymakers in many low and middle income countries need to make difficult decisions about which of the recommended tools and approaches to implement and scale-up. The test characteristics (e.g. sensitivity and specificity) of the tools alone are not a sufficient basis on which to make these decisions as policymakers need to also consider the best combination of tools, whether the new tools should complement or replace existing diagnostics and who should be tested. Diagnostic strategies need dovetailing to different epidemiology and structural resource constraints (e.g. existing diagnostic pathways, human resources and laboratory capacity). We propose operational modelling to assist with these complex decisions. Projections of patient, health system and cost impacts are essential and operational modelling of the relevant elements of the health system could provide these projections and support rational decisions. We demonstrate how the technique of operational modelling applied in the developing world to support decisions on diagnostics for tuberculosis, could in a parallel way, provide useful insights to support implementation of appropriate diagnostic innovations for parasitic diseases.

  19. Expansion of an Existing Water Management Model for the Analysis of Opportunities and Impacts of Agricultural Irrigation under Climate Change Conditions

    Directory of Open Access Journals (Sweden)

    Jörg Steidl

    2015-11-01

    Full Text Available The impact of climate change and increased irrigation area on future hydrologic and agro-economic conditions was analysed for a representative basin in northeastern Germany using an expanded version of the WBalMO (water balance model for water management. The model expansion represents various temporally and spatially differentiated irrigation water use processes, including agricultural irrigation, as part of a river basin’s water management. We show that climate changes lead to increased irrigation water demands in the future, which will not always be able to be met. The resulting water deficits were shown for different crops depending on their irrigation priority and the water available. With an increased irrigation area, water deficits will rise. This may limit the profitability of agricultural irrigation. The impacts of climate change on low-flow conditions in the river are much higher than those of the increase in irrigated area alone. Therefore, any additional increases of irrigation will require careful monitoring of water availability to avoid critical impacts on river flows. The expanded model was able to replicate the processes of agricultural irrigation water use and can thus be used to test the impact of policies such as the certification of new irrigation permits.

  20. Cowichan Valley energy mapping and modelling. Report 4 - Analysis of opportunity costs and issues related to regional energy resilience. Final report. [Vancouver Island, Canada

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-06-15

    The driving force behind the Integrated Energy Mapping and Analysis project was the identification and analysis of a suite of pathways that the Cowichan Valley Regional District (CVRD) can utilise to increase its energy resilience, as well as reduce energy consumption and GHG emissions, with a primary focus on the residential sector. Mapping and analysis undertaken will support provincial energy and GHG reduction targets, and the suite of pathways outlined will address a CVRD internal target that calls for 75% of the region's energy within the residential sector to come from locally sourced renewables by 2050. The target has been developed as a mechanism to meet resilience and climate action target. The maps and findings produced are to be integrated as part of a regional policy framework currently under development. Based on the outputs from the first three tasks, a suite of coherent pathways towards the overall target of 75% residential local energy consumption was created, and the costs and benefits for the region were calculated. This was undertaken via a scenario analysis which also highlighted the risks and robustness of the different options within the pathways. In addition to a direct economic comparison between the different pathways, more qualitative issues were described, including potential local employment, environmental benefits and disadvantages, etc. The main tool utilised in this analysis was a tailor made Excel energy model that includes mechanisms for analysing improvements in the CVRD energy system down to an area level, for example renewable energy in residential buildings, renewable energy generation, and the effects of energy efficiency improvements. For the industrial, commercial, and transport sectors, simple and generic forecasts and input possibilities were included in the model. The Excel 'technology cost' and 'energy' models are accompanied with a user manual so that planners within the CVRD can become well

  1. The Opportunity Cost of Capital

    Directory of Open Access Journals (Sweden)

    Ayman Chit PhD

    2015-04-01

    Full Text Available The opportunity cost of the capital invested in pharmaceutical research and development (R&D to bring a new drug to market makes up as much as half the total cost. However, the literature on the cost of pharmaceutical R&D is mixed on how, exactly, one should calculate this “hidden” cost. Some authors attempt to adopt models from the field of finance, whereas other prominent authors dismiss this practice as biased, arguing that it artificially inflates the R&D cost to justify higher prices for pharmaceuticals. In this article, we examine the arguments made by both sides of the debate and then explain the cost of capital concept and describe in detail how this value is calculated. Given the significant contribution of the cost of capital to the overall cost of new drug R&D, a clear understanding of the concept is critical for policy makers, investors, and those involved directly in the R&D.

  2. Biogas Opportunities Roadmap Progress Report

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2015-12-01

    In support of the Obama Administration's Climate Action Plan, the U.S. Department of Energy, the U.S. Environmental Protection Agency, and U.S. Department of Agriculture jointly released the Biogas Opportunities Roadmap Progress Report, updating the federal government's progress to reduce methane emissions through biogas systems since the Biogas Opportunities Roadmap was completed by the three agencies in July 2014. The report highlights actions taken, outlines challenges and opportunities, and identifies next steps to the growth of a robust biogas industry.

  3. Lightcurve Photometry Opportunities: 2017 April-June

    Science.gov (United States)

    Warner, Brian D.; Harris, Alan W.; Durech, Josef; Benner, Lance A. M.

    2017-04-01

    We present lists of asteroid photometry opportunities for objects reaching a favorable apparition and having either none or poorly-defined lightcurve parameters. Additional data on these objects will help with shape and spin axis modeling via lightcurve inversion. We also include lists of objects that will be the target of radar observations. Lightcurves for these objects can help constrain pole solutions and/or remove rotation period ambiguities that might not come from using radar data alone.

  4. Lightcurve Photometry Opportunities: 2017 January-March

    Science.gov (United States)

    Warner, Brian D.; Harris, Alan W.; Durech, Josef; Benner, Lance A. M.

    2017-01-01

    We present lists of asteroid photometry opportunities for objects reaching a favorable apparition and having either none or poorly-defined lightcurve parameters. Additional data on these objects will help with shape and spin axis modeling via lightcurve inversion. We also include lists of objects that will be the target of radar observations. Lightcurves for these objects can help constrain pole solutions and/or remove rotation period ambiguities that might not come from using radar data alone.

  5. Lightcurve Photometry Opportunities: 2016 October-December

    Science.gov (United States)

    Warner, Brian D.; Harris, Alan W.; Durech, Josef; Benner, Lance A. M.

    2016-10-01

    We present lists of asteroid photometry opportunities for objects reaching a favorable apparition and having either none or poorly-defined lightcurve parameters. Additional data on these objects will help with shape and spin axis modeling via lightcurve inversion. We also include lists of objects that will be the target of radar observations. Lightcurves for these objects can help constrain pole solutions and/or remove rotation period ambiguities that might not come from using radar data alone.

  6. Lightcurve Photometry Opportunities: 2016 April-June

    Science.gov (United States)

    Warner, Brian D.; Harris, Alan W.; Durech, Josef; Benner, Lance A. M.

    2016-04-01

    We present lists of asteroid photometry opportunities for objects reaching a favorable apparition and having either none or poorly-defined lightcurve parameters. Additional data on these objects will help with shape and spin axis modeling via lightcurve inversion. We also include lists of objects that will be the target of radar observations. Lightcurves for these objects can help constrain pole solutions and/or remove rotation period ambiguities that might not come from using radar data alone.

  7. Lightcurve Photometry Opportunities: 2016 July-September

    Science.gov (United States)

    Warner, Brian D.; Harris, Alan W.; Durech, Josef; Benner, Lance A. M.

    2016-07-01

    We present lists of asteroid photometry opportunities for objects reaching a favorable apparition and having either none or poorly-defined lightcurve parameters. Additional data on these objects will help with shape and spin axis modeling via lightcurve inversion. We also include lists of objects that will be the target of radar observations. Lightcurves for these objects can help constrain pole solutions and/or remove rotation period ambiguities that might not come from using radar data alone.

  8. Opportunities in Martensite Theory

    OpenAIRE

    Olson, G.

    1995-01-01

    A workshop has explored interactions of materials science, applied mechanics, physics and mathematics in understanding fundamentals of martensitic transformations. System theory offers a framework for addressing realistic complexity. Theory of invariant-plane kinematics has been extended to multivariant plate groups and hierarchical structures. Electronic total energy calculations explore the origins of martensitic phase stability, and Landau-Ginzberg models for transformations with and witho...

  9. Opportunities of the new technological model of light vehicle fuels in South America; Oportunidades futuras no novo modelo tecnologico de combustiveis para veiculos leves na America do Sul

    Energy Technology Data Exchange (ETDEWEB)

    Dourado, Jose Diamantino de A. [Centro Federal de Educacao Tecnologica Celso Sukow da Fonseca (CEFET-RJ), Rio de Janeiro, RJ (Brazil); Chaves, Hernani Aquini F.; Jones, Cleveland Maximino [Universidade do Estado do Rio de Janeiro (UERJ), Rio de Janeiro, RJ (Brazil). Dept. de Estratigrafia e Paleontologia (DEPA)

    2008-07-01

    The purpose of this work is to show which solutions the South American market is putting forth for the new technological model of the automotive fuel for light duty vehicles. A strong and irreversible trend is underway, which is seeking more environmentally friendly and economically attractive alternatives for the conventional automotive technology, based on the consumption of gasoline and diesel fuel. This trend is evident not only in Latin America, but also in many other countries and regions, and has resulted in a great number of vehicle conversions, so as to operate with vehicular natural gas. Another important way in which this trend has expressed itself is the commercial acceptance and success of the tetra fuel technology vehicles. (author)

  10. Social media: opportunities for quality improvement and lessons for providers-a networked model for patient-centered care through digital engagement.

    Science.gov (United States)

    Bornkessel, Alexandra; Furberg, Robert; Lefebvre, R Craig

    2014-07-01

    Social media brings a new dimension to health care for patients, providers, and their support networks. Increasing evidence demonstrates that patients who are more actively involved in their healthcare experience have better health outcomes and incur lower costs. In the field of cardiology, social media are proposed as innovative tools for the education and update of clinicians, physicians, nurses, and medical students. This article reviews the use of social media by healthcare providers and patients and proposes a model of "networked care" that integrates the use of digital social networks and platforms by both patients and providers and offers recommendations for providers to optimize their use and understanding of social media for quality improvement.

  11. 含交易成本和机会成本的极小极大多期投资组合选择模型%Multi-period minimax portfolio selection model with transaction costs and opportunity costs

    Institute of Scientific and Technical Information of China (English)

    任大源; 徐玖平; 黄南京; 吴萌

    2012-01-01

    This paper deals with a multi-period portfolio selection problem in the frictional market. A multi-period minimax portfolio selection model with opportunity costs and transaction costs is proposed. By using the theory of nonlinear programming, we prove the existence of optimal solution of this model. Moreover, the method for solving this model is given by using the theory of convex programming and Kuhn-Tucker condition. Finally, a numerical example is given to illustrate our results.%本文考虑了摩擦市场下的多期证券投资组合选择问题,利用极小极大原理,建立了在含有机会成本和交易成本的多期极小极大投资组合选择模型.利用非线性规划相关理论,证明了该模型最优解的存在性,并利用凸规划相关理论与Kuhn-Tucker条件给出了求解该模型的一种方法,最后通过实例对结论进行了说明.

  12. Value of Uncertainty: The Lost Opportunities in Large Projects

    Directory of Open Access Journals (Sweden)

    Agnar Johansen

    2016-08-01

    Full Text Available The uncertainty management theory has become well established over the last 20–30 years. However, the authors suggest that it does not fully address why opportunities often remain unexploited. Empirical studies show a stronger focus on mitigating risks than exploiting opportunities. This paper therefore addresses why so few opportunities are explored in large projects. The theory claims that risks and opportunities should be equally managed in the same process. In two surveys, conducted in six (private and public companies over a four-year period, project managers stated that uncertainty management is about managing risk and opportunities. However, two case studies from 12 projects from the same companies revealed that all of them had their main focus on risks, and most of the opportunities were left unexploited. We have developed a theoretical explanation model to shed light on this phenomena. The concept is a reflection based on findings from our empirical data up against current project management, uncertainty, risk and stakeholder literature. Our model shows that the threshold for pursuing a potential opportunity is high. If a potential opportunity should be considered, it must be extremely interesting, since it may require contract changes, and the project must abandon an earlier-accepted best solution.

  13. New Opportunities for Targeted Immunotherapy

    Science.gov (United States)

    A team of NCI researchers has reported that several types of gastrointestinal cancer have tumor-specific mutations that can be recognized by the immune system, thereby offering a new therapeutic opportunity for patients with these tumors.

  14. Analysis of Business Opportunities & Entrepreneurial

    African Journals Online (AJOL)

    ETIWISTIC

    2013-04-29

    Apr 29, 2013 ... psychological risks of starting or running a company or business ... Opportunities for new business ventures come from sources that are as varied ..... There should be room for some degree of uncertainty, essential to locate.

  15. Employment opportunities for the disabled

    NARCIS (Netherlands)

    Delsen, L.W.M.

    1996-01-01

    Policy makers in the OECD Member States have developed quite different programmes and institutional arrangements to create and promote employment opportunities for the disabled. These policy approaches include legal interventions, employment support services, financial support of open employment and

  16. US Forest Service Recreation Opportunities

    Data.gov (United States)

    US Forest Service, Department of Agriculture — A map service on the www depicting the recreation opportunity information that the Forest Service collects through the Recreation Portal and shares with the public...

  17. Wind Technologies & Evolving Opportunities (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Robichaud, R.

    2014-07-01

    This presentation covers opportunities for wind technology; wind energy market trends; an overview of the National Wind Technology Center near Boulder, Colorado; wind energy price and cost trends; wind turbine technology improvements; and wind resource characterization improvements.

  18. Inequality of opportunity in India

    OpenAIRE

    Singh, Ashish

    2010-01-01

    The paper associates inequality of opportunities with outcome differences that can be accounted by pre-determined circumstances which lie beyond the control of an individual, such as parental education, parental occupation, caste, religion and place of birth. The overall opportunity share estimates (parametric) of total consumption expenditure inequality due to a set of circumstances comprising of caste, religion, geographical region, parental education and parental occupation vary from 16% t...

  19. Network marketing as an opportunity

    OpenAIRE

    Hakun, Peter

    2010-01-01

    The objective of this thesis is to clarify network marketing and how it works and to describe its advantages, disadvantages and opportunity which it offers to producer, distributor and consumer. The first chapter gives a definition of network marketing, explains how it works and refers to its history. In the second chapter the network marketing is compared to common distribution chain from producer's as well as consumer's point of view. Opportunities which network marketing offers to a distri...

  20. Network marketing as an opportunity

    OpenAIRE

    Hakun, Peter

    2010-01-01

    The objective of this thesis is to clarify network marketing and how it works and to describe its advantages, disadvantages and opportunity which it offers to producer, distributor and consumer. The first chapter gives a definition of network marketing, explains how it works and refers to its history. In the second chapter the network marketing is compared to common distribution chain from producer's as well as consumer's point of view. Opportunities which network marketing offers to a distri...

  1. Small-scale (flash) flood early warning in the light of operational requirements: opportunities and limits with regard to user demands, driving data, and hydrologic modeling techniques

    Science.gov (United States)

    Philipp, Andy; Kerl, Florian; Büttner, Uwe; Metzkes, Christine; Singer, Thomas; Wagner, Michael; Schütze, Niels

    2016-05-01

    In recent years, the Free State of Saxony (Eastern Germany) was repeatedly hit by both extensive riverine flooding, as well as flash flood events, emerging foremost from convective heavy rainfall. Especially after a couple of small-scale, yet disastrous events in 2010, preconditions, drivers, and methods for deriving flash flood related early warning products are investigated. This is to clarify the feasibility and the limits of envisaged early warning procedures for small catchments, hit by flashy heavy rain events. Early warning about potentially flash flood prone situations (i.e., with a suitable lead time with regard to required reaction-time needs of the stakeholders involved in flood risk management) needs to take into account not only hydrological, but also meteorological, as well as communication issues. Therefore, we propose a threefold methodology to identify potential benefits and limitations in a real-world warning/reaction context. First, the user demands (with respect to desired/required warning products, preparation times, etc.) are investigated. Second, focusing on small catchments of some hundred square kilometers, two quantitative precipitation forecasts are verified. Third, considering the user needs, as well as the input parameter uncertainty (i.e., foremost emerging from an uncertain QPF), a feasible, yet robust hydrological modeling approach is proposed on the basis of pilot studies, employing deterministic, data-driven, and simple scoring methods.

  2. Model of ship's optimization opportunity for taking collision avoidance action in decision-making for collision avoidance%船舶最佳避碰行动时机决策模型

    Institute of Scientific and Technical Information of China (English)

    吴兆麟; 郑中义

    2000-01-01

    Under the consideration of the fuzzy satisfaction degree of stand-on vessel to the time adopted by given-way vessel in collision avoidance, the uncertainty of given-way vessel to take collision avoidance action according to distances and DCPAs, the possibility of stand-on vessel to take herself action of collision avoidance and the last opportunity point to use helm, the model of optimization of time of collision avoidance is established. Based on the investigation to mariners' behavior of collision avoidance the model is used to determine the time of given-way vessel to adopt action of collision avoidance.%在考虑直航船对让路船采取避碰时机模糊满意度、让路船在各距离及最近会遇距离上采取避碰行动不确定性、直航船可能采取避碰行动以及让路船最晚施舵点的基础上,建立了确定让路船最佳避碰时机模型.根据对船员避碰行为调查,应用该模型确定了让路船最佳避碰时机.

  3. OPPORTUNITY OF GOODWILL DEPRECIATION IN EMERGING MARKETS

    Directory of Open Access Journals (Sweden)

    Radu-Daniel LOGHIN

    2015-04-01

    Full Text Available In order to influence the decisions of the users of financial situations, the financial data concerning the commercial fund must be communicated in an opportune manner. Information like depreciation and amortization must comprise the changes from the competitive environment of the enterprise. The work aims at developing such a model for the evaluation of the opportunity of decision of the commercial fund at the level of 262 bursary titles from the emergent markets, showing that this decision is influenced by the bursary performance on a short term of the title as well as its shocks on the short term, but not by the bursary performance. The paper reveals the fact that the development of the emergent markets requires greater attention of the management for the recent events.

  4. Collaboration opportunities in advanced housing renovation

    DEFF Research Database (Denmark)

    Mlecnik, Erwin; Kondratenko, Irena; Cré, Johan

    2012-01-01

    identified key supply-side needs through interviews and questionnaires, and analysed important elements for the development of a web-based portal that can connect supply and demand. The project further developed ideas and methods for collaboration and business model generation between different players...... demand for integrated renovations has to be stimulated. A research and networking methodology was developed within the framework of the One Stop Shop project to identify and develop collaboration opportunities for advanced housing renovation in Belgium, Denmark, Finland and Norway. The research...... on the renovation market. These different research results contributed to defining new business opportunities related to process innovation to unburden the homeowner and to achieve less fragmented renovation processes...

  5. Missed opportunities in child healthcare

    Directory of Open Access Journals (Sweden)

    Linda Jonker

    2014-01-01

    Full Text Available Background: Various policies in health, such as Integrated Management of Childhood Illnesses, were introduced to enhance integrated service delivery in child healthcare. During clinical practice the researcher observed that integrated services may not be rendered.Objectives: This article describes the experiences of mothers that utilised comprehensive child health services in the Cape Metropolitan area of South Africa. Services included treatment for diseases; preventative interventions such as immunisation; and promotive interventions, such as improvement in nutrition and promotion of breastfeeding.Method: A qualitative, descriptive phenomenological approach was applied to explore the experiences and perceptions of mothers and/or carers utilising child healthcare services. Thirty percent of the clinics were selected purposively from the total population. A convenience purposive non-probability sampling method was applied to select 17 mothers who met the criteria and gave written consent. Interviews were conducted and recorded digitally using an interview guide. The data analysis was done using Tesch’s eight step model.Results: Findings of the study indicated varied experiences. Not all mothers received information about the Road to Health book or card. According to the mothers, integrated child healthcare services were not practised. The consequences were missed opportunities in immunisation, provision of vitamin A, absence of growth monitoring, feeding assessment and provision of nutritional advice.Conclusion: There is a need for simple interventions such as oral rehydration, early recognition and treatment of diseases, immunisation, growth monitoring and appropriate nutrition advice. These services were not offered diligently. Such interventions could contribute to reducing the incidence of child morbidity and mortality.

  6. The Influence Factors,Opportunities and Obstacles of Business Model Innovation in the New Energy Industry%新能源产业商业模式创新的影响因素、机会与障碍

    Institute of Scientific and Technical Information of China (English)

    邢相军

    2014-01-01

    The influence factors of business model innovation in the new energy industry include both the external and internal factors. The external factors include such factors as market demand,policy orientation,technological drivers and the characteristics of target groups;while the internal factors include such factors as industrial features,the current situation of profit earning,and entrepreneurs’quality. The integration process of enterprises and the environment,the restructuring of value chain and the reorganization of enterprises’internal unit are the opportunities for the business model innovation in the new energy industry. The enterprises should correctly identify the opportunities and obstacles in the process of business innovation,adapt to the development trend of economic globalization and informationization to contribute to the sustainable social and economic development of China.%新能源产业商业模式创新的影响因素包括外部因素和内部因素,市场需求、政策导向、技术驱动和目标群体特征是外部影响因素的主要内容,而行业特征、盈利现状、企业家素质则是其内部影响因素;企业与所处环境的融合过程,与供应商、客户、合作伙伴价值链的重构以及企业内部单元的调整重组构成了新能源产业商业模式创新的机会。企业应正确识别商业模式创新过程中的机会和障碍,适应经济全球化和信息化的发展趋势,为我国社会与经济的持续发展作出贡献。

  7. Career opportunities in clinical engineering.

    Science.gov (United States)

    Morse, W A

    1992-01-01

    The varied career opportunities open to clinical engineers are described in this paper. Many of these opportunities are within the medical device industry in research, development, manufacturing design, regulatory activities, production, operations, sales, marketing, service, and management. Additional opportunities are available in hospitals, with the Veterans Administration, or working as an entrepreneur or a consultant. Each of these careers requires specific training and skills, and they all require a fundamental scientific knowledge of physical principles and mathematics. Research and management, however, require different educational preparation. The research emphasis should be on theoretical principles and creativity; the management emphasis should be on financial and labor problems. In all clinical engineering careers, the individual is a problem solver.

  8. The Man and the Opportunity

    Institute of Scientific and Technical Information of China (English)

    Orison; Swett; Marden; 詹比发

    2003-01-01

    选注者言:人生不得志者,往往将自己的失意归咎于命运之不公、机会之不肯眷顾!本文从一个全新的视角,向人们揭示机会的本质:Opportunities!Every lifeis full of them.成事纵然在天,谋事还须在人。让我们把此句当作座右铭:Golden opportunities are nothing to laziness,but industry makes the commonestchances golden.

  9. TEACHER TALK AND LEARNER OPPORTUNITY

    Institute of Scientific and Technical Information of China (English)

    LanWeidong

    2004-01-01

    Adopting the position that maximizing learner involvement is conducive to second language acquisition, this paper aims to explore the relationship between teacher talk and learner opportunities in language classrooms in senior schools through classroom observation techniques. Four excellent high school teachers from Zhejiang province in China are involved in this research. The results reveal that such features as minimal teacher talking time, referential questions, extended wait time,discoursal feedback can increase potential of learning opportunities through classroom interaction in language classrooms in high schools.

  10. Postdoctoral Opportunities and Career Options

    Science.gov (United States)

    Manka, R. H.

    2001-05-01

    Following the completion of a Ph.D. degree, in the sciences a postdoctoral appointment has traditionally been a key step in career development to expand the student's background and broaden their perspective. The postdoctoral appointment often is almost a requirement to obtain some positions in academia and government laboratories. In addition, postdoctoral positions in industry are becoming more common and offer an opportunity to explore a field without making a long-term commitment. We describe the nature of a postdoctoral appointment and discuss the advantages and disadvantages of the recent Ph.D. taking a postdoctoral position. We comment on the role such positions play in university, government and the corporate research. Finally, we describe some of the national postdoctoral opportunities that exist including large programs offered by the National Research Council through Federal laboratories including those of NASA, NOAA, EPA, and the Department of Defense. Exciting new interdisciplinary opportunities such as fellowships at the NASA Astrobiology Institute are summarized, as are international opportunities such as the von Humboldt fellowships in Germany.

  11. Graduate Opportunities for Black Students.

    Science.gov (United States)

    Paynter, Julie, Ed.

    This document catalogues graduate opportunities specifically for black students in 1969-70 at 42 universities, 96 additional graduate departments (social sciences, natural sciences, mathematics, and humanities), and 111 additional professional schools (particularly social work, education, law, medicine, theology, business, and library science).…

  12. Nikola Tesla Educational Opportunity School.

    Science.gov (United States)

    Design Cost Data, 2001

    2001-01-01

    Describes the architectural design, costs, general description, and square footage data for the Nikola Tesla Educational Opportunity School in Colorado Springs, Colorado. A floor plan and photos are included along with a list of manufacturers and suppliers used for the project. (GR)

  13. Opportunities and Internationalisation of PSFs

    DEFF Research Database (Denmark)

    Jensen, Søren Henning; Poulfelt, Flemming

    2017-01-01

    The article focuses on the relationship between internationalisation and opportunities of firms within the professional services industry. The key question explored is whether internationalisation of PSFs is a passive strategy driven by clients' internationalisation or if it is a deliberate searc...

  14. Nikola Tesla Educational Opportunity School.

    Science.gov (United States)

    Design Cost Data, 2001

    2001-01-01

    Describes the architectural design, costs, general description, and square footage data for the Nikola Tesla Educational Opportunity School in Colorado Springs, Colorado. A floor plan and photos are included along with a list of manufacturers and suppliers used for the project. (GR)

  15. Investment opportunities with YPFB capitalization

    Energy Technology Data Exchange (ETDEWEB)

    Escobar, F. [Yacimientos Petroliferos Fiscales Bolivianos, La Paz (Bolivia)

    1996-10-01

    Investment opportunities with Yacimientos Petroliferos Fiscales Bolivianos (LPFB) in La Paz, Bolivia, were discussed, especially as they may be affected by the new Hydrocarbon Law No. 1689, whose main objective is to encourage investments in Bolivia and to increase production capacity through investors` incorporation. Some of the areas of potential importance examined included reserve development, transportation, upstream consulting, and hydrocarbon development.

  16. Using Activity Theory to Understand Entrepreneurial Opportunity

    Science.gov (United States)

    Holt, Robin

    2008-01-01

    Entrepreneurship is often described as the ability to recognize and exploit opportunities. Identifying opportunities is intentional and idiosyncratic insofar as they are recognized as opportunities is a novel and conscious event (otherwise the entrepreneur would be doing nothing new). Yet opportunities also have to be recognized by others as ones…

  17. Using Activity Theory to Understand Entrepreneurial Opportunity

    Science.gov (United States)

    Holt, Robin

    2008-01-01

    Entrepreneurship is often described as the ability to recognize and exploit opportunities. Identifying opportunities is intentional and idiosyncratic insofar as they are recognized as opportunities is a novel and conscious event (otherwise the entrepreneur would be doing nothing new). Yet opportunities also have to be recognized by others as ones…

  18. Opportunities and Challenges Facing Chinese Manufacturing under New Model of Intelligent Manufacturing%智能制造新模式下"中国制造"面临的机遇和挑战

    Institute of Scientific and Technical Information of China (English)

    伏琳

    2016-01-01

    According to the background of a new round of global technological and industrial revolution, combined with develop-ment condition in manufacturing industry in China, the opportunities and challenges faced under new model of intelligent manufacturing were analyzed. It was put forward for development of the intelligent manufacturing that two development routes should be made sure, as well as of propelled gradually construction of intelligent factory with classified levels and in step by step. Then, product technology in-novation should be paid more attention, and product quality and reliability levels improved to enhance competitiveness. Finlay, services in intelligent product and intelligent manufacturing must be developed with a great effort to promote intelligent manufacturing model widely used in industry.%以全球新一轮科技革命和产业变革为背景,结合我国制造业发展情况,分析了在智能制造新生产模式下我国制造业发展面临的机遇和挑战,提出了发展智能制造要明确两条发展路线,明确要分层次、 分步骤逐步推进智能工厂建设,并注重产品技术创新,提升产品质量可靠性水平,大力发展智能产品和智能制造服务业,最终推动智能制造模式在工业领域的广泛应用.

  19. Research by residents: obstacles and opportunities.

    Science.gov (United States)

    Torous, John; Padmanabhan, Jaya

    2015-02-01

    As the psychiatric field continues to evolve in a world with nascent mobile technology (Hilty et al., 2014), novel neuroscience and genetic research, and new payment and care models (Fried et al., 2014) it is likely that the psychiatry residents learn today will not match what they will be practicing tomorrow. Residents have the opportunity to help shape that future through conducting research today. While the prospect of research can initially seem daunting to the busy resident, here we examine, from psychiatry residents' perspective, the common pitfalls and rewards of research during residency.

  20. Market Opportunities and Barriers for Smart Buildings

    DEFF Research Database (Denmark)

    Ma, Zheng; Badi, Adrian; Jørgensen, Bo Nørregaard

    2016-01-01

    conducts a qualitative approach with primary and secondary data to investigate the Barriers and opportunities of the construction companies into the smart building market. The result shows the willingness of the players to involve the building efficiency business with huge potential monetary benefits...... 2011. Much research already shows the players' passive and conservative attitudes to enter into the energy efficiency market. Especially there are obstacles for the construction companies to redesign their business model from the traditional building business to the smart building market. This paper...

  1. Issues and Opportunities in Exotic Hadrons

    CERN Document Server

    Briceno, R A; Coito, S; Dudek, J J; Eichten, E; Fischer, C S; Fritsch, M; Gradl, W; Jackura, A; Kornicer, M; Krein, G; Lebed, R F; Machado, F A; Mitchell, R E; Morningstar, C J; Peardon, M; Pennington, M R; Peters, K; Richard, J -M; Shen, C -P; Shepherd, M R; Skwarnicki, T; Swanson, E S; Szczepaniak, A P; Yuan, C -Z

    2015-01-01

    The last few years have been witness to a proliferation of new results concerning heavy exotic hadrons. Experimentally, many new signals have been discovered that could be pointing towards the existence of tetraquarks, pentaquarks, and other exotic configurations of quarks and gluons. Theoretically, advances in lattice field theory techniques place us at the cusp of understanding complex coupled-channel phenomena, modelling grows more sophisticated, and effective field theories are being applied to an ever greater range of situations. It is thus an opportune time to evaluate the status of the field. In the following, a series of high priority experimental and theoretical issues concerning heavy exotic hadrons is presented.

  2. Activism and the Online Mediation Opportunity Structure

    DEFF Research Database (Denmark)

    Uldam, Julie

    2013-01-01

    The annual United Nations (UN) Framework Convention on Climate Change conferences provides a transnational mediation opportunity structure for activist networks to contest policies that favor market-based models for solving the climate crisis. Online technologies, including commercial social media...... to climate change activism. This impedes possibilities for using online media to protest at the radical end of the climate justice movement spectrum. This article explores this interrelationship between activist demands and (online) modes of action through a focus on the mobilization efforts of London...

  3. Network Virtualization - Opportunities and Challenges for Operators

    Science.gov (United States)

    Carapinha, Jorge; Feil, Peter; Weissmann, Paul; Thorsteinsson, Saemundur E.; Etemoğlu, Çağrı; Ingþórsson, Ólafur; Çiftçi, Selami; Melo, Márcio

    In the last few years, the concept of network virtualization has gained a lot of attention both from industry and research projects. This paper evaluates the potential of network virtualization from an operator's perspective, with the short-term goal of optimizing service delivery and rollout, and on a longer term as an enabler of technology integration and migration. Based on possible scenarios for implementing and using network virtualization, new business roles and models are examined. Open issues and topics for further evaluation are identified. In summary, the objective is to identify the challenges but also new opportunities for telecom operators raised by network virtualization.

  4. Recent Opportunity Microscopic Imager Results

    Science.gov (United States)

    Herkenhoff, K. E.; Arvidson, R. E.; Jolliff, B. L.; Yingst, R.; Team, A.

    2013-12-01

    Opportunity arrived at exposures of Endeavour crater rim rocks in August 2011, on a hill dubbed 'Cape York.' These rocks have been the goal of exploration by Opportunity for the past few years because spectral evidence for phyllosilicates was observed at this location in orbital remote sensing data. As Opportunity circum¬navigated Cape York, the Microscopic Imager (MI) was used to examine the fine-scale textures of various soils and rocky outcrops. As reported previously, Opportunity discovered multiple bright linear features along the western periphery of Cape York that have been interpreted as veins of Ca sulfate deposited in fractures within the bedrock of Cape York. Opportunity then explored the northern and eastern sides of Cape York, including the area around 'Matijevic Hill' that shows evidence for phyllosilicates in CRISM data acquired from the Mars Reconnaissance Orbiter. One of the first outcrops examined near Matijevic Hill, dubbed 'Kirkwood,' is dominated by millimeter-size spherules. Unlike the hematite-rich concretions observed by Opportunity on Meridiani Planum, the aggregated 'newberries' in the Kirkwood exposure display internal structure and resistant rims. Compositionally, the spherule-rich rock is very similar to a nearby spherule-poor outcrop dubbed 'Whitewater Lake.' Thus these spherules have a more basalt-like composition compared to the hematite-rich concretions of the Burns Formation. The origin of the Kirkwood outcrop is uncertain, but the setting on the rim of the 22-km diameter Endeavour crater suggests that perhaps impact melting was involved in lapilli formation, possibly followed by mobilization and sorting in the ejecta blanket. Alternatively, the newberries may be diagenetic iron oxide concretions that are less well cemented than the 'blueberries' of the younger sulfate-rich Burns Formation. The Whitewater Lake outcrops contain the phyllosilicate phases observed from orbit, and are the oldest materials yet investigated by

  5. Novel opportunities for computational biology and sociology in drug discovery☆

    Science.gov (United States)

    Yao, Lixia; Evans, James A.; Rzhetsky, Andrey

    2013-01-01

    Current drug discovery is impossible without sophisticated modeling and computation. In this review we outline previous advances in computational biology and, by tracing the steps involved in pharmaceutical development, explore a range of novel, high-value opportunities for computational innovation in modeling the biological process of disease and the social process of drug discovery. These opportunities include text mining for new drug leads, modeling molecular pathways and predicting the efficacy of drug cocktails, analyzing genetic overlap between diseases and predicting alternative drug use. Computation can also be used to model research teams and innovative regions and to estimate the value of academy–industry links for scientific and human benefit. Attention to these opportunities could promise punctuated advance and will complement the well-established computational work on which drug discovery currently relies. PMID:20349528

  6. Novel opportunities for computational biology and sociology in drug discovery

    Science.gov (United States)

    Yao, Lixia

    2009-01-01

    Drug discovery today is impossible without sophisticated modeling and computation. In this review we touch on previous advances in computational biology and by tracing the steps involved in pharmaceutical development, we explore a range of novel, high value opportunities for computational innovation in modeling the biological process of disease and the social process of drug discovery. These opportunities include text mining for new drug leads, modeling molecular pathways and predicting the efficacy of drug cocktails, analyzing genetic overlap between diseases and predicting alternative drug use. Computation can also be used to model research teams and innovative regions and to estimate the value of academy-industry ties for scientific and human benefit. Attention to these opportunities could promise punctuated advance, and will complement the well-established computational work on which drug discovery currently relies. PMID:19674801

  7. Digital watermarking opportunities enabled by mobile media proliferation

    Science.gov (United States)

    Modro, Sierra; Sharma, Ravi K.

    2009-02-01

    Consumer usages of mobile devices and electronic media are changing. Mobile devices now include increased computational capabilities, mobile broadband access, better integrated sensors, and higher resolution screens. These enhanced features are driving increased consumption of media such as images, maps, e-books, audio, video, and games. As users become more accustomed to using mobile devices for media, opportunities arise for new digital watermarking usage models. For example, transient media, like images being displayed on screens, could be watermarked to provide a link between mobile devices. Applications based on these emerging usage models utilizing watermarking can provide richer user experiences and drive increased media consumption. We describe the enabling factors and highlight a few of the usage models and new opportunities. We also outline how the new opportunities are driving further innovation in watermarking technologies. We discuss challenges in market adoption of applications based on these usage models.

  8. Novel opportunities for computational biology and sociology in drug discovery.

    Science.gov (United States)

    Yao, Lixia; Evans, James A; Rzhetsky, Andrey

    2010-04-01

    Current drug discovery is impossible without sophisticated modeling and computation. In this review we outline previous advances in computational biology and, by tracing the steps involved in pharmaceutical development,explore a range of novel, high-value opportunities for computational innovation in modeling the biological process of disease and the social process of drug discovery.These opportunities include text mining for new drug leads, modeling molecular pathways and predicting the efficacy of drug cocktails, analyzing genetic overlap between diseases and predicting alternative drug use.Computation can also be used to model research teams and innovative regions and to estimate the value of academy-industry links for scientific and human benefit. Attention to these opportunities could promise punctuated advance and will complement the well-established computational work on which drug discovery currently relies.

  9. The flipped classroom: practices and opportunities for health sciences librarians.

    Science.gov (United States)

    Youngkin, C Andrew

    2014-01-01

    The "flipped classroom" instructional model is being introduced into medical and health sciences curricula to provide greater efficiency in curriculum delivery and produce greater opportunity for in-depth class discussion and problem solving among participants. As educators employ the flipped classroom to invert curriculum delivery and enhance learning, health sciences librarians are also starting to explore the flipped classroom model for library instruction. This article discusses how academic and health sciences librarians are using the flipped classroom and suggests opportunities for this model to be further explored for library services.

  10. UTBB FDSOI: Evolution and opportunities

    Science.gov (United States)

    Monfray, Stephane; Skotnicki, Thomas

    2016-11-01

    As today's 28 nm FDSOI (Fully Depleted Silicon On Insulator) technology is at the industrialization level, this paper aims to summarize the key advantages allowed by the thin BOX (Buried Oxide) of the FDSOI, through the technology evolution but also new opportunities, among logic applications and extending the possibilities offered by the platform. We will summarize how the advantages provided by the thin BOX have been first explored and developed, and how the back biasing techniques are the key to the outstanding performances provided by the FDSOI at low voltage. Then, as the FDSOI technology is also a solution to develop innovative platforms and applications, we will detail some opportunities. In particular, we will present monolithic 3D integration, ultra-low power devices for IoT (Internet of Things) and ultra-sensitive sensors.

  11. Opportunity Structures for Selective Exposure

    DEFF Research Database (Denmark)

    Skovsgaard, Morten; Shehata, Adam; Strömbäck, Jesper

    2016-01-01

    is to investigate the two types of selective exposure in a country—Sweden—where the opportunity structures for selective exposure differ from the American context. This study investigates both types of selective exposure in relation to televised party-leader interviews. Based on panel survey data, the findings show...... interest. Evidence for both has been found primarily in an American context, while there is less research on European countries. This is problematic, as the opportunity structures for different forms of selectivity vary across media environments. Against this background, the purpose of this study...... that selective exposure based on political interest is substantially more important than selective exposure based on ideological preferences in explaining exposure to party-leader interviews. To substantiate this finding, the results are replicated with partisan learning as the dependent variable....

  12. Eand P opportunities in Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Castilho, Marcelo [National Petroleum Agency of Brasil (Brazil)

    2011-07-01

    Brazil is one of the world's largest economies and the country also has significant heavy oil reserves. This report from the National Petroleum Agency of Brazil aims at presenting the situation of the oil and gas sector in Brazil in terms of resources, production, regulatory framework and opportunities for the future. Brazil has numerous sedimentary basins at its disposal, most of them being prospected by both national and foreign companies from all over the world. Brazil has over 14 billion barrels of proven reserves, its production is 2,1 MMBbl/d and heavy oil represents almost 40% of that production. The National Petroleum Agency of Brazil is responsible for the implementation of oil sector policy with the aims of maintaining self-sufficiency, implementing good practices in terms of health and safety, and increasing local content. This paper pointed out that Brazil has an important opportunity to enhance its energy sector through the development of heavy oil.

  13. Equal opportunity in the workplace.

    Science.gov (United States)

    Allen, A

    1992-04-01

    The Equal Employment Opportunity Commission (EEOC) was created by the Civil Rights Act of 1964. The commission encourages voluntary compliance with equal employment opportunity practices, and has authority to investigate complaints alleging discrimination in hiring, firing, wage rates, testing, training, apprenticeship, and other conditions of employment. In October 1991, during the Senate Judiciary Committee hearings, the confirmation of Judge Clarence Thomas for a seat on the United States Supreme Court was placed in jeopardy by a charge of sexual harassment while Thomas was head of the EEOC. This article focuses on aspects of sexual harassment in the workplace, the role of the EEOC, and offers some suggestions for keeping the work environment free of abusive behavior.

  14. The phosphoric acid leak from the wreck of the MV Ece in the English Channel in 2006: Assessment with a ship of opportunity, an operational ecosystem model and historical data.

    Science.gov (United States)

    Kelly-Gerreyn, Boris A; Hydes, David J; Hartman, Mark C; Siddorn, John; Hyder, Patrick; Holt, Martin W

    2007-07-01

    This study evaluates the ship of opportunity (Ferrybox) concept for both sustained monitoring of UK shelf sea waters and numerical model validation. Release of phosphate from the wreck of a chemical tanker (MV Ece) in the western English Channel (49.73 degrees N, 3.25 degrees W) in March 2006 is used to demonstrate the importance of sustained observations in decision support systems and policy development. The Ferrybox system continuously collects sea surface (5m) data from a suite of autonomous electronic sensors installed on a passenger ferry operating year-round between Portsmouth (UK) and Bilbao (Spain). The detection of anomalously high concentrations of phosphate (1.54mmolm(-3), four times the usual level) and onset of phytoplankton growth close to the wreck site in March 2006 was placed in the context of multiple years of measurements (phosphate, nitrate, silicate and chlorophyll) collected from the Ferrybox system (2003-2006) and the long-term time series station E1 (50.03 degrees N, 4.65 degrees W, 1930-1987) in the English Channel. With regard to decision support, release of phosphate from the tanker is unlikely to pose a threat as phytoplankton growth at the end of winter is not unusual in this region and dissolved inorganic nitrogen rather than phosphate (DIN:DIP=10-18) is likely to ultimately limit algal growth in spring 2006. With regard to policy development, the Oslo and Paris (OSPAR) commissions recommendation of sampling every three years in "non-problem areas" is likely to provide statistically inadequate data, given the interannual and decadal variability identified in the Ferrybox and E1 data: the Ferrybox data show that oceanic winter nutrient concentrations varied by 35-50% between 2003/2004 and 2005/2006 due to deeper mixing of water off-shelf in early 2005/2006 and comparisons between the Ferrybox and E1 years show that the western English Channel is currently experiencing a low in phosphate concentrations similar to those in the 1960s. The

  15. Future Mission Proposal Opportunities: Discovery, New Frontiers, and Project Prometheus

    Science.gov (United States)

    Niebur, S. M.; Morgan, T. H.; Niebur, C. S.

    2003-01-01

    The NASA Office of Space Science is expanding opportunities to propose missions to comets, asteroids, and other solar system targets. The Discovery Program continues to be popular, with two sample return missions, Stardust and Genesis, currently in operation. The New Frontiers Program, a new proposal opportunity modeled on the successful Discovery Program, begins this year with the release of its first Announcement of Opportunity. Project Prometheus, a program to develop nuclear electric power and propulsion technology intended to enable a new class of high-power, high-capability investigations, is a third opportunity to propose solar system exploration. All three classes of mission include a commitment to provide data to the Planetary Data System, any samples to the NASA Curatorial Facility at Johnson Space Center, and programs for education and public outreach.

  16. Brexit: potential opportunities, potential risks.

    Science.gov (United States)

    2017-01-21

    ▪ Identifying opportunities and risks that might arise from the UK's exit from the European Union▪ Managing mental health issues and building resilient teams▪ Supporting efforts to eliminate rabiesThese were among matters discussed by the BVA Council at its meeting on December 7, 2016. The BVA President, Gudrun Ravetz, chaired the meeting, which was held at the BVA's headquarters in Mansfield Street, London. British Veterinary Association.

  17. US maglev: Status and opportunities

    Energy Technology Data Exchange (ETDEWEB)

    Coffey, H.T.

    1992-01-01

    Recognizing the development of maglev systems in Germany and Japan, and the growing congestion, air pollution and energy consumption resulting from our current transportation system, the United States, in 1990, embarked on a program to evaluate the potential usefulness of these systems in the US. In this paper, the utility of maglev systems in alleviating some of these problems, progress in the current program, and opportunities for participation by the superconductivity and cryogenic communities are discussed.

  18. US maglev: Status and opportunities

    Energy Technology Data Exchange (ETDEWEB)

    Coffey, H.T.

    1992-09-01

    Recognizing the development of maglev systems in Germany and Japan, and the growing congestion, air pollution and energy consumption resulting from our current transportation system, the United States, in 1990, embarked on a program to evaluate the potential usefulness of these systems in the US. In this paper, the utility of maglev systems in alleviating some of these problems, progress in the current program, and opportunities for participation by the superconductivity and cryogenic communities are discussed.

  19. Reminder - Equal Opportunities Advisory Panel

    CERN Multimedia

    HR Department

    2007-01-01

    At its meeting on 7 December 2006, the Standing Concertation Committee also took note of the nomination of a fourth new member of the Panel: Wisla Carena. The present composition of the Panel (appointed ad personam) is now as follows: Tiziano Camporesi (Chairperson), Wisla Carena, Pierre Charrue, Sue Foffano, Josi Schinzel (Equal Opportunities Officer), Markus Nordberg, Christine Petit-Jean-Genaz and Elena Wildner. Human Resources Department Tel. 74480

  20. A ‘Smart’ Opportunity

    DEFF Research Database (Denmark)

    Breitenbauch, Henrik Ø.; Giegerich, Bastian

    2012-01-01

    cooperation, however, leads industry to think about cooperation mostly in terms of delays and market-distorting principles. With this backward-looking mindset, industry risks missing a crucial growth potential, a market that will only exist because of Smart Defense. Across the Atlantic, industry should seize...... this opportunity as eagerly as it would any good business development prospect. Simply put, the Smart Defense framework will offer a way to sell products that would not otherwise be sold....

  1. Decadal opportunities for space architects

    Science.gov (United States)

    Sherwood, Brent

    2012-12-01

    A significant challenge for the new field of space architecture is the dearth of project opportunities. Yet every year more young professionals express interest to enter the field. This paper derives projections that bound the number, type, and range of global development opportunities that may be reasonably expected over the next few decades for human space flight (HSF) systems so those interested in the field can benchmark their goals. Four categories of HSF activity are described: human Exploration of solar system bodies; human Servicing of space-based assets; large-scale development of space Resources; and Breakout of self-sustaining human societies into the solar system. A progressive sequence of capabilities for each category starts with its earliest feasible missions and leads toward its full expression. The four sequences are compared in scale, distance from Earth, and readiness. Scenarios hybridize the most synergistic features from the four sequences for comparison to status quo, government-funded HSF program plans. Finally qualitative, decadal, order-of-magnitude estimates are derived for system development needs, and hence opportunities for space architects. Government investment towards human planetary exploration is the weakest generator of space architecture work. Conversely, the strongest generator is a combination of three market drivers: (1) commercial passenger travel in low Earth orbit; (2) in parallel, government extension of HSF capability to GEO; both followed by (3) scale-up demonstration of end-to-end solar power satellites in GEO. The rich end of this scale affords space architecture opportunities which are more diverse, complex, large-scale, and sociologically challenging than traditional exploration vehicle cabins and habitats.

  2. Engineering ethics challenges and opportunities

    CERN Document Server

    Bowen, W Richard

    2014-01-01

    Engineering Ethics: Challenges and Opportunities aims to set a new agenda for the engineering profession by developing a key challenge: can the great technical innovation of engineering be matched by a corresponding innovation in the acceptance and expression of ethical responsibility?  Central features of this stimulating text include:   ·         An analysis of engineering as a technical and ethical practice providing great opportunities for promoting the wellbeing and agency of individuals and communities. ·         Elucidation of the ethical opportunities of engineering in three key areas:             - Engineering for Peace, emphasising practical amelioration of the root causes of    conflict rather than military solutions.             - Engineering for Health, focusing on close collaboration with healthcare professionals      for both the promotion and restoration of health.             - Engineering for Development, providing effective solution...

  3. Compelling Research Opportunities using Isotopes

    Energy Technology Data Exchange (ETDEWEB)

    None

    2009-04-23

    Isotopes are vital to the science and technology base of the US economy. Isotopes, both stable and radioactive, are essential tools in the growing science, technology, engineering, and health enterprises of the 21st century. The scientific discoveries and associated advances made as a result of the availability of isotopes today span widely from medicine to biology, physics, chemistry, and a broad range of applications in environmental and material sciences. Isotope issues have become crucial aspects of homeland security. Isotopes are utilized in new resource development, in energy from bio-fuels, petrochemical and nuclear fuels, in drug discovery, health care therapies and diagnostics, in nutrition, in agriculture, and in many other areas. The development and production of isotope products unavailable or difficult to get commercially have been most recently the responsibility of the Department of Energy's Nuclear Energy program. The President's FY09 Budget request proposed the transfer of the Isotope Production program to the Department of Energy's Office of Science in Nuclear Physics and to rename it the National Isotope Production and Application program (NIPA). The transfer has now taken place with the signing of the 2009 appropriations bill. In preparation for this, the Nuclear Science Advisory Committee (NSAC) was requested to establish a standing subcommittee, the NSAC Isotope Subcommittee (NSACI), to advise the DOE Office of Nuclear Physics. The request came in the form of two charges: one, on setting research priorities in the short term for the most compelling opportunities from the vast array of disciplines that develop and use isotopes and two, on making a long term strategic plan for the NIPA program. This is the final report to address charge 1. NSACI membership is comprised of experts from the diverse research communities, industry, production, and homeland security. NSACI discussed research opportunities divided into three areas: (1

  4. The Role of Different Opportunities in the Activation and Use of the Business Opportunity Prototype

    NARCIS (Netherlands)

    Costa, Silvia F.; Ehrenhard, Michel L.; Caetano, Antonio; Santos, Susana C.

    2016-01-01

    This study analyses how the different nature of business opportunities affects the way potential entrepreneurs recognize a business opportunity prototypical features. Although scholars have examined the reasons why some individuals, but not others, identify business opportunities, little is known ab

  5. Neuroepigenomics: resources, obstacles, and opportunities

    Directory of Open Access Journals (Sweden)

    John S. Satterlee

    2015-01-01

    Full Text Available Long-lived postmitotic cells, such as most human neurons, must respond effectively to ongoing changes in neuronal stimulation or microenvironmental cues through transcriptional and epigenomic regulation of gene expression. The role of epigenomic regulation in neuronal function is of fundamental interest to the neuroscience community, as these types of studies have transformed our understanding of gene regulation in postmitotic cells. This perspective article highlights many of the resources available to researchers interested in neuroepigenomic investigations and discusses some of the current obstacles and opportunities in neuroepigenomics.

  6. Strengths, weaknesses, opportunities and threats

    DEFF Research Database (Denmark)

    Bull, J. W.; Jobstvogt, N.; Böhnke-Henrichs, A.;

    2016-01-01

    environmental awareness. Threats include resistance to change, and difficulty with interdisciplinary collaboration. Consideration of SWOT themes suggested five strategic areas for developing and implementing ES.The ES concept could improve decision-making related to natural resource use, and interpretation...... facilitate interdisciplinary research, ensuring decision-making that supports sustainable development........ Such an assessment could form the basis for improving ES thinking, further embedding it into environmental decisions and management.The Young Ecosystem Services Specialists (YESS) completed a Strengths-Weaknesses-Opportunities-Threats (SWOT) analysis of ES through YESS member surveys. Strengths include the approach...

  7. Energy Development Opportunities for Wyoming

    Energy Technology Data Exchange (ETDEWEB)

    Larry Demick

    2012-11-01

    The Wyoming Business Council, representing the state’s interests, is participating in a collaborative evaluation of energy development opportunities with the NGNP Industry Alliance (an industry consortium), the University of Wyoming, and the US Department of Energy’s Idaho National Laboratory. Three important energy-related goals are being pursued by the State of Wyoming: Ensuring continued reliable and affordable sources of energy for Wyoming’s industries and people Restructuring the coal economy in Wyoming Restructuring the natural gas economy in Wyoming

  8. Educational Homogamy: Preferences or Opportunities?

    DEFF Research Database (Denmark)

    Nielsen, Helena Skyt; Svarer, Michael

    Individuals match on length and type of education. We investigate whether thesystematic relationship between educations of partners is explained by opportuni-ties (e.g. low search frictions) or preferences (e.g. complementarities in householdproduction or portfolio optimization). We find that half...... of the systematic sortingon education is due to low search frictions in marriage markets of the educationalinstitutions. The other half is attributed to complementarities in household pro-duction, since income properties of the joint income process show no influence on partner selection....

  9. Educational Homogamy: Preferences or Opportunities?

    DEFF Research Database (Denmark)

    Nielsen, Helena Skyt; Svarer, Michael

    Individuals match on length and type of education. We investigate whether thesystematic relationship between educations of partners is explained by opportuni-ties (e.g. low search frictions) or preferences (e.g. complementarities in householdproduction or portfolio optimization). We find that half...... of the systematic sortingon education is due to low search frictions in marriage markets of the educationalinstitutions. The other half is attributed to complementarities in household pro-duction, since income properties of the joint income process show no influence on partner selection....

  10. 12 CFR 563.201 - Corporate opportunity.

    Science.gov (United States)

    2010-01-01

    ...-OPERATIONS Reporting and Bonding § 563.201 Corporate opportunity. (a) If you are a director or officer of a... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Corporate opportunity. 563.201 Section 563.201... duty to a savings association, you must not take advantage of corporate opportunities belonging to...

  11. Logistics opportunity costs: A mining case study

    Directory of Open Access Journals (Sweden)

    Leani van Jaarsveld

    2013-05-01

    Full Text Available This study highlighted the importance of determining the impact that an ineffective mode of transport has on a firm’s transportation model and costs. The main focus of this study was to determine the logistics opportunity costs of using road transport within a mining firm. A case study approach was followed, as the investigation aimed to analyse a complex problem experienced by one company and present it in an easily understandable format. From the results of this study, it was apparent that the logistics opportunity costs associated with the mode of transport was substantial. This highlighted the need for firms to revise their choice of transport mode on a regular basis, as it has a major impact not only on their transportation costs, but also on their inventory holding and carbon emissions. The results also have implications for South Africa’s only freight railway, Transnet Freight Rail, which should not only focus on expanding its existing capacity, but also on improving its customer service delivery whilst containing tariff increases.

  12. An Aging Workforce: Employment Opportunities and Obstacles

    Directory of Open Access Journals (Sweden)

    Full Professor, Institute of Economic Sciences

    2013-05-01

    Full Text Available The last decade has witnessed significant changes in the structure of unemployment in the global labour market. This is corroborated by the fact that the global workforce is rapidly aging and the share of people aged 50 and over in the structure of the labour market is increasing. In line with this trend, unemployment issues should be considered as a global problem that cannot be fully resolved at the level of any individual country separately.The main objective of this paper is to throw some light on the aging workforce and the elderly population’s opportunity to realise their right to work and be treated equally with younger age groups. Hence, the paper simultaneously focuses on the age and gender discrimination of elderly population in terms of their employment prospects. The aim of our research is not only to point out certain stereotypes concerning the elderly labour force, but also to stress that unless preconditions for overcoming these stereotypes are created and employment opportunities are given to this segment of the labour force, full employment as an ultimate goal of global economic policy cannot be achieved. It is in accordance with these considerations that we offer a model to achieve this goal.

  13. Is Primatology an equal-opportunity discipline?

    Directory of Open Access Journals (Sweden)

    Elsa Addessi

    Full Text Available The proportion of women occupying academic positions in biological sciences has increased in the past few decades, but women are still under-represented in senior academic ranks compared to their male colleagues. Primatology has been often singled out as a model of "equal-opportunity" discipline because of the common perception that women are more represented in Primatology than in similar fields. But is this indeed true? Here we show that, although in the past 15 years the proportion of female primatologists increased from the 38% of the early 1990s to the 57% of 2008, Primatology is far from being an "equal-opportunity" discipline, and suffers the phenomenon of "glass ceiling" as all the other scientific disciplines examined so far. In fact, even if Primatology does attract more female students than males, at the full professor level male members significantly outnumber females. Moreover, regardless of position, IPS male members publish significantly more than their female colleagues. Furthermore, when analyzing gender difference in scientific productivity in relation to the name order in the publications, it emerged that the scientific achievements of female primatologists (in terms of number and type of publications do not always match their professional achievements (in terms of academic position. However, the gender difference in the IPS members' number of publications does not correspond to a similar difference in their scientific impact (as measured by their H index, which may indicate that female primatologists' fewer articles are of higher impact than those of their male colleagues.

  14. Arctic resources : a mechatronics opportunity

    Energy Technology Data Exchange (ETDEWEB)

    McKean, M.; Baiden, G. [Penguin Automated Systems Inc., Naughton, ON (Canada)

    2008-07-01

    This paper discussed the telerobotic mechatronics opportunities that exist to access mineral resources in the Arctic. The Mining Automation Project (MAP) determined that telerobotics could contribute to productivity gains while providing increased worker safety. The socio-economic benefits of advanced mechatronics for Arctic resource development are particularly attractive due to reduced infrastructure needs; operating costs; and environmental impacts. A preliminary analysis of mining transportation options by the authors revealed that there is a case for in-situ resource utilization (ISRU) for oil and gas processing to address resource development. The ISRU options build on concepts developed to support space exploration and were proposed to reduce or modify transportation loads to allow more sustainable and efficient Arctic resource development. Many benefits in terms of efficiency could be achieved by combining demonstrated mechatronics with ISRU because of the constrained transportation infrastructure in the Arctic. In the context of harsh environment operations, mechatronics may provide an opportunity for undersea resource facilities. 15 refs., 6 figs.

  15. Analysis of Opportunity to Learn for Students with Disabilities: Effects of Standards-Aligned Instruction

    Science.gov (United States)

    Blank, Rolf K.; Smithson, John L.

    2014-01-01

    The paper presents a model for addressing the critical question of opportunity to learn for students with disabilities. The model was tested through a two-year study with schools and teachers in three states. Opportunity to learn analysis is critical in this educational era of push toward access and inclusion. The study results indicate that…

  16. Interfaces - Weak Links, Yet Great Opportunities

    Science.gov (United States)

    Hendricks, Robert C.; Dimofte, Florin; Chupp, Raymond E.; Steinetz, Bruce M.

    2011-01-01

    Inadequate turbomachine interface design can rapidly degrade system performance, yet provide great opportunity for improvements. Engineered coatings of seals and bearing interfaces are major issues in the operational life of power systems. Coatings, films, and combined use of both metals and ceramics play a major role in maintaining component life. Interface coatings, like lubricants, are sacrificial for the benefit of the component. Bearing and sealing surfaces are routinely protected by tribologically paired coatings such as silicon diamond like coatings (SiDLC) in combination with an oil lubricated wave bearing that prolongs bearing operational life. Likewise, of several methods used or researched for detecting interface failures, dopants within coatings show failures in functionally graded ceramic coatings. The Bozzolo-Ferrante-Smith (BFS) materials models and quantum mechanical tools, employed in interface design, are discussed.

  17. Tuberculosis Immunity: Opportunities from Studies with Cattle

    Directory of Open Access Journals (Sweden)

    W. Ray Waters

    2011-01-01

    Full Text Available Mycobacterium tuberculosis and M. bovis share >99% genetic identity and induce similar host responses and disease profiles upon infection. There is a rich history of codiscovery in the development of control measures applicable to both human and bovine tuberculosis (TB including skin-testing procedures, M. bovis BCG vaccination, and interferon-γ release assays. The calf TB infection model offers several opportunities to further our understanding of TB immunopathogenesis. Recent observations include correlation of central memory immune responses with TB vaccine efficacy, association of SIRPα+ cells in ESAT-6:CFP10-elicited multinucleate giant cell formation, early γδ T cell responses to TB, antimycobacterial activity of memory CD4+ T cells via granulysin production, association of specific antibody with antigen burden, and suppression of innate immune gene expression in infected animals. Partnerships teaming researchers with veterinary and medical perspectives will continue to provide mutual benefit to TB research in man and animals.

  18. Physics opportunities with meson beams

    Energy Technology Data Exchange (ETDEWEB)

    Briscoe, William J.; Doering, Michael; Haberzettl, Helmut; Strakovsky, Igor I. [The George Washington University, Washington, DC (United States); Manley, D.M. [Kent State University, Kent, OH (United States); Naruki, Megumi [Kyoto University, Kyoto (Japan); Swanson, Eric S. [University of Pittsburgh, Pittsburgh, PA (United States)

    2015-10-15

    Over the past two decades, meson photo- and electroproduction data of unprecedented quality and quantity have been measured at electromagnetic facilities worldwide. By contrast, the meson-beam data for the same hadronic final states are mostly outdated and largely of poor quality, or even non-existent, and thus provide inadequate input to help interpret, analyze, and exploit the full potential of the new electromagnetic data. To reap the full benefit of the high-precision electromagnetic data, new high-statistics data from measurements with meson beams, with good angle and energy coverage for a wide range of reactions, are critically needed to advance our knowledge in baryon and meson spectroscopy and other related areas of hadron physics. To address this situation, a state-of-the-art meson-beam facility needs to be constructed. The present paper summarizes unresolved issues in hadron physics and outlines the vast opportunities and advances that only become possible with such a facility. (orig.)

  19. Opportunity structures for selective exposure

    DEFF Research Database (Denmark)

    Skovsgaard, Morten; Shehata, Adam; Strömbäck, Jesper

    2016-01-01

    Abstract The transition from low-choice to high-choice media environments has raised new concerns about selective exposure. In this context, two types of selective media exposure are relevant. One is selectivity based on political ideological preferences, the other selectivity based on political...... interest. Evidence for both has been found primarily in an American context, while there is less research on European countries. This is problematic, as the opportunity structures for different forms of selectivity vary across media environments. Against this background, the purpose of this study...... that selective exposure based on political interest is substantially more important than selective exposure based on ideological preferences in explaining exposure to party-leader interviews. To substantiate this finding, the results are replicated with partisan learning as the dependent variable....

  20. CORIDORS: DEVELOPMENT OPPORTUNITY OF SERBIA

    Directory of Open Access Journals (Sweden)

    Laketa Marko

    2011-12-01

    Full Text Available Long-term vision of the Republic of Serbia is for it to be: territorially determined and regionally balanced, of sustainable economic growth and competitive, socially coherent and stable, infrastructurally equipped and accessible in terms of transportation, of preserved and protected natural and cultural heritage, high-quality living environment and functionally integrated into environment. High-quality transportation infrastructure is one of the main conditions of linking and integration into a broader environment. The aim of this paper is to show, based on the identification of the effects expected (internal and external, that Corridors 7 and 10, as logistics resources, are a development opportunity of Serbia and that its realization will multiply contribute to the achievement of long-term development goals of Serbia.

  1. Biomass Business Opportunities Viet Nam

    Energy Technology Data Exchange (ETDEWEB)

    Zwebe, D. [SNV Netherlands Development Organisation, Ha Noi (Viet Nam)

    2012-03-15

    The goal of this survey is to provide a more specific and integral perspective in which niches, relevant policy development by the Vietnamese government, legislation and sustainability criteria are clearly addressed to benefit both the Dutch Private sector as well as to stimulate Dutch-Vietnamese cooperation and support the Vietnamese government in its search for tangible options to develop the desired enabling environment for a sustainable biomass/biofuel market. The following activities are defined to be executed to reach the goal of the project: Biomass availability in Vietnam (Chapter 2); Government of Vietnam and Energy (Chapter 3); The opportunities and barriers to enter the market in Vietnam (Chapter 4 and 5); Stakeholder analysis of the bio-energy sector (Chapter 6); and Recommendations (Chapter 7)

  2. Angiogenesis and Its Therapeutic Opportunities

    Directory of Open Access Journals (Sweden)

    So Young Yoo

    2013-01-01

    Full Text Available Angiogenesis plays critical roles in human physiology that range from reproduction and fetal growth to wound healing and tissue repair. The sophisticated multistep process is tightly regulated in a spatial and temporal manner by “on-off switch signals” between angiogenic factors, extracellular matrix components, and endothelial cells. Uncontrolled angiogenesis may lead to several angiogenic disorders, including vascular insufficiency (myocardial or critical limb ischemia and vascular overgrowth (hemangiomas, vascularized tumors, and retinopathies. Thus, numerous therapeutic opportunities can be envisaged through the successful understanding and subsequent manipulation of angiogenesis. Here, we review the clinical implications of angiogenesis and discuss pro- and antiangiogenic agents that offer potential therapy for cancer and other angiogenic diseases.

  3. Opportunities From the Digital Revolution

    Directory of Open Access Journals (Sweden)

    Louise Corti

    2016-11-01

    Full Text Available In the 1990s, the term “online” research emerged as a new and vibrant suite of methods, focused on exploitation of sources not collected by traditional social science methods. Today, at least one part of the research life cycle is likely to be carried out “online,” from data collection through to publishing. In this article, we seek to understand emergent modes of doing and reporting qualitative research “online.” With a greater freedom now to term oneself a “researcher,” what opportunities and problems do working with online data sources bring? We explore implications of emerging requirements to submit supporting data for social science journal articles and question whether these demands might disrupt the very nature of and identity of qualitative research. Finally, we examine more recent forms of publishing and communicating research that support outputs where data play an integral role in elucidating context and enhancing the reading experience.

  4. Photovoltaic research opportunities. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Macaleer, B.; Bowers, J.; Hurlburt, B.

    1985-11-19

    The purpose of this study is to identify opportunities for photovoltaic (PV) research projects to capitalize on related but non-PV research. The study is performed under the assumption that a considerable body of ongoing semiconductor research in non-PV areas could be of value to its PV Program and the PV community in general. Research related to III-V compounds, thin films, and crystalline silicon materials is included. Research that is known to be PV-related or sponsored by DOE was excluded from consideration. The study resulted in 11 recommendations (research areas) and a subset of 58 specific research projects. In addition, over 75 non-PV research managers in the semiconductor field are identified as potential sources of ideas which could benefit photovoltaics.

  5. Photovoltaic research opportunities. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Macaleer, B.; Bowers, J.; Hurlburt, B.

    1985-11-19

    The purpose of this study is to identify opportunities for photovoltaic (PV) research projects to capitalize on related but non-PV research. The study is performed under the assumption that a considerable body of ongoing semiconductor research in non-PV areas could be of value to its PV Program and the PV community in general. Research related to III-V compounds, thin films, and crystalline silicon materials is included. Research that is known to be PV-related or sponsored by DOE was excluded from consideration. The study resulted in 11 recommendations (research areas) and a subset of 58 specific research projects. In addition, over 75 non-PV research managers in the semiconductor field are identified as potential sources of ideas which could benefit photovoltaics.

  6. Challenges and opportunities in presbycusis.

    Science.gov (United States)

    Parham, Kourosh; McKinnon, Brian J; Eibling, David; Gates, George A

    2011-04-01

    The population aged 65 years and older is increasing at a faster rate than the total population, with predictions that by 2030, 20% of the population will be 65 years or older. In 2006, between 35% and 50% of those aged 65 years or older reportedly had presbycusis, a sensory impairment that contributes to social isolation and loss of autonomy and is associated with anxiety, depression, and cognitive decline. To address these concerns, the Geriatric Committee of the American Academy of Otolaryngology, in conjunction with the Hearing Committee, focused on 3 challenges and opportunities in the management of presbycusis: (1) the financial burden of caring for patients with presbycusis in the face of increasing costs and declining reimbursements; (2) future treatment options arising from improved understanding of the molecular mechanisms underlying presbycusis, and (3) recognition of central presbycusis as a condition commonly superimposed on peripheral age-related hearing loss whose diagnosis and management can improve outcomes.

  7. Physics Opportunities with Meson Beams

    CERN Document Server

    Briscoe, William J; Haberzettl, Helmut; Manley, D Mark; Naruki, Megumi; Strakovsky, Igor I; Swanson, Eric S

    2015-01-01

    Over the past two decades, meson photo- and electro-production data of unprecedented quality and quantity have been measured at electromagnetic facilities worldwide. By contrast, the meson-beam data for the same hadronic final states are mostly outdated and largely of poor quality, or even nonexistent, and thus provide inadequate input to help interpret, analyze, and exploit the full potential of the new electromagnetic data. To reap the full benefit of the high-precision electromagnetic data, new high-statistics data from measurements with meson beams, with good angle and energy coverage for a wide range of reactions, are critically needed to advance our knowledge in baryon and meson spectroscopy and other related areas of hadron physics. To address this situation, a state of-the-art meson-beam facility needs to be constructed. The present paper summarizes unresolved issues in hadron physics and outlines the vast opportunities and advances that only become possible with such a facility.

  8. Plastics recycling: challenges and opportunities.

    Science.gov (United States)

    Hopewell, Jefferson; Dvorak, Robert; Kosior, Edward

    2009-07-27

    Plastics are inexpensive, lightweight and durable materials, which can readily be moulded into a variety of products that find use in a wide range of applications. As a consequence, the production of plastics has increased markedly over the last 60 years. However, current levels of their usage and disposal generate several environmental problems. Around 4 per cent of world oil and gas production, a non-renewable resource, is used as feedstock for plastics and a further 3-4% is expended to provide energy for their manufacture. A major portion of plastic produced each year is used to make disposable items of packaging or other short-lived products that are discarded within a year of manufacture. These two observations alone indicate that our current use of plastics is not sustainable. In addition, because of the durability of the polymers involved, substantial quantities of discarded end-of-life plastics are accumulating as debris in landfills and in natural habitats worldwide. Recycling is one of the most important actions currently available to reduce these impacts and represents one of the most dynamic areas in the plastics industry today. Recycling provides opportunities to reduce oil usage, carbon dioxide emissions and the quantities of waste requiring disposal. Here, we briefly set recycling into context against other waste-reduction strategies, namely reduction in material use through downgauging or product reuse, the use of alternative biodegradable materials and energy recovery as fuel. While plastics have been recycled since the 1970s, the quantities that are recycled vary geographically, according to plastic type and application. Recycling of packaging materials has seen rapid expansion over the last decades in a number of countries. Advances in technologies and systems for the collection, sorting and reprocessing of recyclable plastics are creating new opportunities for recycling, and with the combined actions of the public, industry and governments it

  9. Plastics recycling: challenges and opportunities

    Science.gov (United States)

    Hopewell, Jefferson; Dvorak, Robert; Kosior, Edward

    2009-01-01

    Plastics are inexpensive, lightweight and durable materials, which can readily be moulded into a variety of products that find use in a wide range of applications. As a consequence, the production of plastics has increased markedly over the last 60 years. However, current levels of their usage and disposal generate several environmental problems. Around 4 per cent of world oil and gas production, a non-renewable resource, is used as feedstock for plastics and a further 3–4% is expended to provide energy for their manufacture. A major portion of plastic produced each year is used to make disposable items of packaging or other short-lived products that are discarded within a year of manufacture. These two observations alone indicate that our current use of plastics is not sustainable. In addition, because of the durability of the polymers involved, substantial quantities of discarded end-of-life plastics are accumulating as debris in landfills and in natural habitats worldwide. Recycling is one of the most important actions currently available to reduce these impacts and represents one of the most dynamic areas in the plastics industry today. Recycling provides opportunities to reduce oil usage, carbon dioxide emissions and the quantities of waste requiring disposal. Here, we briefly set recycling into context against other waste-reduction strategies, namely reduction in material use through downgauging or product reuse, the use of alternative biodegradable materials and energy recovery as fuel. While plastics have been recycled since the 1970s, the quantities that are recycled vary geographically, according to plastic type and application. Recycling of packaging materials has seen rapid expansion over the last decades in a number of countries. Advances in technologies and systems for the collection, sorting and reprocessing of recyclable plastics are creating new opportunities for recycling, and with the combined actions of the public, industry and governments it

  10. Energy efficiency opportunities in Hotels

    Directory of Open Access Journals (Sweden)

    Dina Said

    2017-03-01

    Full Text Available According to the statistics in Egypt (2013, the number of hotels is 1193, about 407 of them have contracted power greater than 500 kW.Air conditioning, lighting, water heating and refrigeration represent the main activities demanding electrical energy in hotel business.The energy consumption per night spend changes a lot, depending on various factors; facilities provided, category of hotel, occupancy , geographical situation, weather conditions, nationality of clients, design and control of the installations.Energy benchmarking is an internal management tool designed to provide ongoing, reliable and verifiable tracking on the hotels performance. The most useful performance indicator (or Energy Efficiency Benchmarking of hotels are: Lighting Power Density (LPD in W (for lighting/m2, and energy intensity (kWh/m2/ y.There are multiple benefits for improving energy in hotel business; reduces the hotel's operating cost, reduces climate change risks and promotes green tourism.Energy efficiency opportunities are low-cost measures and cost- effective investments.   There are many energy saving opportunities for lighting in hotel's guest rooms as well as the more obvious savings in lobbies and exterior lighting areas. Behavior campaigns can yield substantial energy savings, both through the guests and housekeeper behavior. Encouraging housekeepers to use natural light during room cleaning is a simple first step to implement energy saving program.This paper presents the energy efficiency guidelines and energy benchmarking for hotels. Also a case study showing how the energy efficiency program implemented is presented. 

  11. Future practice risks: obstacles with opportunities.

    Science.gov (United States)

    Mallory, Thomas H

    2003-02-01

    The encouragement of a consumer-directed insurance market and the involvement of corporate America have led to a transformation of the healthcare system that will redefine patient expectations and the role of the physician. The expectation of a higher level of customer service, the role of electronic media, and an earnest regard for healthcare by the patient will impact the physician. Consumer-directed healthcare will call for a reprioritization, focusing on service, convenience, competency, quality, and low cost. Indifference to patient courtesies or failure to become involved in modern technology may cause the physician to be bypassed from this new healthcare system. As the business world integrates the business model into the medical profession, healthcare organizations will restructure themselves into well-organized business enterprises employing physicians. The singular physician may no longer be competitive with such business enterprises, leading to consolidation of organizations and a significant decision for the physician. The physician will have the unusual opportunity to either remain exclusively a medical professional or to also venture into the business world as an equity investor, participating in financial growth possibilities of those medical practice organizations that are for-profit. With the emergence of these new equity models of healthcare, the primary focus will be on profit, production, and service efficiencies. It is the responsibility of the physician to maintain professionalism and the commitment to quality and appropriateness of patient care. However, at the same time, the physician has the unique opportunity to participate in the distribution, economics, and subsequent financial profit of healthcare. The medical experience of the physician, coupled with business acumen, will be an unbeatable combination.

  12. Opportunity for selection in human health.

    Science.gov (United States)

    Govindaraju, Diddahally R

    2014-01-01

    Natural selection defined by differential survival and reproduction of individuals in populations is influenced by genetic, developmental, and environmental factors operating at every age and stage in human life history: generation of gametes, conception, birth, maturation, reproduction, senescence, and death. Biological systems are built upon a hierarchical organization nesting subcellular organelles, cells, tissues, and organs within individuals, individuals within families, and families within populations, and the latter among other populations. Natural selection often acts simultaneously at more than one level of biological organization and on specific traits, which we define as multilevel selection. Under this model, the individual is a fundamental unit of biological organization and also of selection, imbedded in a larger evolutionary context, just as it is a unit of medical intervention imbedded in larger biological, cultural, and environmental contexts. Here, we view human health and life span as necessary consequences of natural selection, operating at all levels and phases of biological hierarchy in human life history as well as in sociological and environmental milieu. An understanding of the spectrum of opportunities for natural selection will help us develop novel approaches to improving healthy life span through specific and global interventions that simultaneously focus on multiple levels of biological organization. Indeed, many opportunities exist to apply multilevel selection models employed in evolutionary biology and biodemography to improving human health at all hierarchical levels. Multilevel selection perspective provides a rational theoretical foundation for a synthesis of medicine and evolution that could lead to discovering effective predictive, preventive, palliative, potentially curative, and individualized approaches in medicine and in global health programs. Copyright © 2014 Elsevier Inc. All rights reserved.

  13. Opportunities for Neutrino Physics at the Spallation Neutron Source (SNS)

    CERN Document Server

    Efremenko, Yu

    2008-01-01

    In this paper we discuss opportunities for a neutrino program at the Spallation Neutrons Source (SNS) being commissioning at ORNL. Possible investigations can include study of neutrino-nuclear cross sections in the energy rage important for supernova dynamics and neutrino nucleosynthesis, search for neutrino-nucleus coherent scattering, and various tests of the standard model of electro-weak interactions.

  14. Introducing Opportunity-based Entrepreneurship in a Transition Economy

    DEFF Research Database (Denmark)

    Perunovic, Zoran

    2005-01-01

    This paper confronts necessity-based and opportunity-based entrepreneurial concepts in the transition of developing economies. The author constructs a research model and conducts field research (using Serbia as a case study) to explore how different personal and regional characteristics can favour......-up strategy for transition and developing economies....

  15. Reciprocal relationships between job demands, job resources, and recovery opportunities

    NARCIS (Netherlands)

    A. Rodríguez-Muñoz (Alfredo); A.I. Sanz-Vergel (Ana Isabel); E. Demerouti (Eva); A.B. Bakker (Arnold)

    2012-01-01

    textabstractThe aim of this study was to explore longitudinal relationships between job demands, job resources, and recovery opportunities. On the basis of the Job Demands-Resources model and Conservation of Resources theory we hypothesized that we would find reciprocal relations between job demands

  16. Symposium on Career Opportunities in Biomedical and Public Health Sciences

    Science.gov (United States)

    Sullivan, Walter W.

    1997-01-01

    The goal of the Symposium on Career Opportunities in Biomedical and Public Health Sciences is to encourage minority collegiate and junior and senior high school students to pursue careers in biomedical and public health sciences. The objectives of the Symposium are to: (1) Provide information to participants concerning biomedical and public health science careers in government, academe and industry; (2) Provide information to minority students about training activities necessary to pursue a biomedical or public health science career and the fiscal support that one can obtain for such training; and (3) Provide opportunities for participating minority biomedical and public health role models to interact with participants.

  17. Energy Savings Potential and Research & Development Opportunities for Commercial Refrigeration

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2009-09-01

    This study documents the energy consumption of commercial refrigeration equipment (CRE) in the U.S. and evaluated the energy savings potential of various technologies and energy efficiency measures that could be applied to such equipment. The study provided an overview of CRE applications, assessed the energy-savings potential of CRE in the U.S., outline key barriers to adoption of energy-savings technologies, and recommended opportunities for advanced energy saving technology research. The study was modeled after an earlier 1996 report by Arthur D. Little, Inc., and updated key information, examined more equipment types, and outlined long-term research and development opportunities.

  18. Windows of Opportunity for Groundwater Management

    Science.gov (United States)

    Foster, T.; Brozovic, N.; Butler, A. P.

    2015-12-01

    To date, there has been little attention focused on how the value and effectiveness of groundwater management is influenced by the timing of regulatory intervention relative to aquifer depletion. To address this question, we develop an integrated framework that couples an agro-economic model of farmers' field-level irrigation decision-making with a model of a groundwater abstraction borehole. Unlike existing models that only consider the impact of aquifer depletion on groundwater extraction costs, our model also captures the dynamic changes in well productivity and how these in turn affect crop yields and farmer incomes. We use our model to analyze how the value of imposing groundwater quotas is affected by the prior level of depletion before regulations are introduced. Our results demonstrate that there is a range of aquifer conditions within which regulating groundwater use will deliver long-term economic benefits for farmers. In this range, restricting abstraction rates slows the rate of change in well yields and, as a result, increases agricultural production over the simulated planning horizon. Contrastingly, when current saturated thickness is outside this range, regulating groundwater use will provide negligible social benefits and will impose large negative impacts on farm-level profits. We suggest that there are 'windows of opportunity' for managing aquifer depletion that are a function of local hydrology as well as economic characteristics. Regulation that is too early will harm the rural economy needlessly, while regulation that is too late will be unable to prevent aquifer exhaustion. The insights from our model can be a valuable tool to help inform policy decisions about when, and at what level, regulations should be implemented in order to maximize the benefits obtained from limited groundwater resources.

  19. Opportunities of Continuing Adult Education

    Directory of Open Access Journals (Sweden)

    Lidija Ušeckienė

    2011-04-01

    Full Text Available After becoming the member state of the European Union, Lithuania undertook all the obligations of a member state. One of them is the implementation of The Lisbon Strategy aiming at the worlds most dynamic and competitive knowledge– based economy by 2010. Under the strategy, a stronger economy will drive job creation, sustainable development, and social inclusion. These changes demand the modernisation of education systems in the E U states, Lithuania among them. To achieve this objective, political forces came to an agreement on the future of Lithuanian education. In 2003 The Seimas of the Republic of Lithuania approved of National Education Strategy 2003–2012. This strategy is special not only because it is based on the experiences of the reform, addresses current and future world’s challenges and opportunities, maintains links with other strategic national reforms, but also emphasises efforts to ensure quality lifelong education for Lithuanian population and striving to become a partner in modern knowledge-based economy. Therefore, an extensive discussion on lifelong education strategies on individual and institution levels in all spheres of social and personal life has started in the E U and Lithuania. Nowadays lifelong learning is not just one aspect of education and training; it gradually is becoming the most important principle in the continuum of complex learning contexts. Such vision must be implemented this decade. The object of the research: the preconditions for the development of continuing adult education. The aim of the research: to examine the peculiarities of the preconditions for the development of continuing adult education in Pakruojis region. The methods of the research: analysis of references and documents on education; an anonymous survey in written form (a questionnaire; statistical analysis of data. The sample. The research was conducted in Pakruojis region in January-April, 2006. 300 respondents of different age

  20. CRISIS LEADERSHIP - AN ORGANIZATIONAL OPPORTUNITY

    Directory of Open Access Journals (Sweden)

    James E. Prewitt

    2011-09-01

    Full Text Available Reactive leadership and crisis management have been synonymous for years. This flows from the belief that crisis is unpredictable and unexpected, which is simply not true. Crisis has its genesis in the values, beliefs, culture, or behavior of an organization which become incongruent with the milieu in which the organization operates. A leader, who is able to read the signals of looming crisis and understands how to harness the exigency brought on by the situation, can diminish the potential dangers and take full advantage of the resulting opportunities. This paper presents a generic crisis lifecycle as a representation of overall crisis. Since a crisis can be broken down into three unique phases, crisis lifecycles can be understood and utilized for the benefit of the organization. In the first phase of the lifecycle, the organization finds itself mired in a static phase which equates to a comfort zone. In this first phase leaders struggle when they attempt to introduce change or learning due to the organizations preference to avoid conflict and maintain stasis. When a crisis engulfs an organization then the stasis that envelops the organization evaporates and gives rise to the second phase or the disaster phase. The disaster phase often threatens the very existence of the organization. When the organization successfully eliminates the immediate organizational threat, the organization is able to enter the adjustive phase of the crisis lifecycle. In this third phase, the leader has the undivided attention of the organization and the underlying urgency to solve the issues that led to the crisis in the first place. Regrettably, many leaders don’t take advantage of this golden opportunity and push the organization back toward the status-quo which ensures that the crisis will return in force. The study of crisis leadership has become more important since the dawn of the new millennium because leaders in all areas face differing degrees of crisis in

  1. A multidisciplinary conceptualization of conservation opportunity.

    Science.gov (United States)

    Moon, Katie; Adams, Vanessa M; Januchowski-Hartley, Stephanie R; Polyakov, Maksym; Mills, Morena; Biggs, Duan; Knight, Andrew T; Game, Edward T; Raymond, Christopher M

    2014-12-01

    An opportunity represents an advantageous combination of circumstances that allows goals to be achieved. We reviewed the nature of opportunity and how it manifests in different subsystems (e.g., biophysical, social, political, economic) as conceptualized in other bodies of literature, including behavior, adoption, entrepreneur, public policy, and resilience literature. We then developed a multidisciplinary conceptualization of conservation opportunity. We identified 3 types of conservation opportunity: potential, actors remove barriers to problem solving by identifying the capabilities within the system that can be manipulated to create support for conservation action; traction, actors identify windows of opportunity that arise from exogenous shocks, events, or changes that remove barriers to solving problems; and existing, everything is in place for conservation action (i.e., no barriers exist) and an actor takes advantage of the existing circumstances to solve problems. Different leverage points characterize each type of opportunity. Thus, unique stages of opportunity identification or creation and exploitation exist: characterizing the system and defining problems; identifying potential solutions; assessing the feasibility of solutions; identifying or creating opportunities; and taking advantage of opportunities. These stages can be undertaken independently or as part of a situational analysis and typically comprise the first stage, but they can also be conducted iteratively throughout a conservation planning process. Four types of entrepreneur can be identified (business, policy, social, and conservation), each possessing attributes that enable them to identify or create opportunities and take advantage of them. We examined how different types of conservation opportunity manifest in a social-ecological system (the Great Barrier Reef) and how they can be taken advantage of. Our multidisciplinary conceptualization of conservation opportunity strengthens and

  2. Applied Geophysics Opportunities in the Petroleum Industry

    Science.gov (United States)

    Olgaard, D. L.; Tikku, A.; Roberts, J. C.; Martinez, A.

    2012-12-01

    Meeting the increasing global demand for energy over the next several decades presents daunting challenges to engineers and scientists, including geoscientists of all disciplines. Many opportunities exist for geophysicists to find and produce oil and gas in a safe, environmentally responsible and affordable manner. Successful oil and gas exploration involves a 'Plates to Pores' approach that integrates multi-scale data from satellites, marine and land seismic and non-seismic field surveys, lab experiments, and even electron microscopy. The petroleum industry is at the forefront of using high performance computing to develop innovative methods to process and analyze large volumes of seismic data and perform realistic numerical modeling, such as finite element fluid flow and rock deformation simulations. Challenging and rewarding jobs in exploration, production and research exist for students with BS/BA, MS and PhD degrees. Geophysics students interested in careers in the petroleum industry should have a broad foundation in science, math and fundamental geosciences at the BS/BA level, as well as mastery of the scientific method, usually gained through thesis work at MS and PhD levels. Field geology or geophysics experience is also valuable. Other personal attributes typical for geoscientists to be successful in industry include a passion for solving complex geoscience problems, the flexibility to work on a variety of assignments throughout a career and skills such as teamwork, communication, integration and leadership. In this presentation we will give examples of research, exploration and production opportunities for geophysicists in petroleum companies and compare and contrast careers in academia vs. industry.

  3. Research opportunities in photochemical sciences

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-07-01

    The workshop entitled {open_quotes}Research Opportunities in Photochemical Sciences{close_quotes} was initiated by the U.S. Department of Energy (DOE), Office of Energy Research (ER), Office of Basic Energy Sciences (BES), Division of Chemical Sciences. The National Renewable Energy Laboratory (NREL) in Golden, Colorado was requested by ER to host the workshop. It was held February 5-8, 1996 at the Estes Park Conference Center, Estes Park, CO, and attended by about 115 leading scientists and engineers from the U.S., Japan, and Europe; program managers for the DOE ER and Energy Efficiency and Renewable Energy (EERE) programs also attended. The purpose of the workshop was to bridge the communication gap between the practioneers and supporters of basic research in photochemical science and the practioneers and supporters of applied research and development in technologies related to photochemical science. For the purposes of the workshop the definition of the term {open_quotes}photochemical science{close_quotes} was broadened to include homogeneous photochemistry, heterogeneous photochemistry, photoelectrochemistry, photocatalysis, photobiology (for example, the light-driven processes of biological photosynthesis and proton pumping), artificial photosynthesis, solid state photochemistry, and solar photochemistry. The technologies under development through DOE support that are most closely related to photochemical science, as defined above, are the renewable energy technologies of photovoltaics, biofuels, hydrogen energy, carbon dioxide reduction and utilization, and photocatalysis for environmental cleanup of water and air. Individual papers were processed separately for the United states Department of Energy databases.

  4. Tuberculosis diagnostics: Challenges and opportunities

    Directory of Open Access Journals (Sweden)

    Vijay Nema

    2012-01-01

    Full Text Available Tuberculosis (TB has been a disease affecting almost all parts of the world since ages. Lot many efforts came in the past for improving diagnosis and treatment. Also, an effective vaccine has been sought after for long. With the emergence of resistant strains of Mycobacterium tuberculosis, the causal organisms of tuberculosis, and complexities emerging due to other associated infections and disease conditions, there is a desperate need for further research input in the field. Be it the better medication and care or better resistance management, proper diagnostics holds the key to success. It has been observed that a high burden of the disease was accompanied by resource limitations and poor research set-up. The scenario remained like this for several decades. With the refreshed vision of resourceful countries and funding agencies, funding is being provided in many areas of research in tuberculosis diagnosis and treatment. This review has been written with an aim to bring forth the limitations of available methods in the field of diagnostics and making researchers aware about the changing scenario with better funding opportunities and support. The author visualizes an enthusiasm from all over the world for the development of better modalities and urges scientists to join the struggle at this very perfect time to take the challenge and come forward with innovations in this field.

  5. Market opportunity in computational proteomics.

    Science.gov (United States)

    Razvi, Enal

    2002-03-01

    The current exuberance on the potential of proteomics as a means to deploy the wealth of the human genome is expected to last into the coming years. Unlike the genome, a finite entity with a fixed number of base pairs of the genetic material, the proteome is "plastic", changing throughout growth and development and environmental stresses, as well as in pathological situations. Our proteomes change over time, and therefore there is no one proteome; the proteome is for practical purposes an infinite entity. It is therefore crucial to build systems that are capable of manipulating the information content that is the proteome, thence the need for computational proteomics as a discipline. In this Market View article, we present the industry landscape that is emerging in the computational proteomics space. This space is still in its infancy and for the most part undefined; therefore we seek to present the market opportunity in informatics in the drug discovery space and then extend that to an examination of industry trends in proteomics. Thus, the gestalt is a set of predictions as to the evolution of the landscape in computational proteomics over the coming years.

  6. Obesogenic environment – intervention opportunities

    Directory of Open Access Journals (Sweden)

    Mauro Fisberg

    2016-06-01

    Full Text Available ABSTRACT Objectives: To evaluate environmental obesogenic-related factors, such as physical activity in neighborhoods and schools, nutritional behavior, and intervention programs. Sources: Critical analysis of literature with personal point of view from infant obesity experts and political advisors for public intervention. Data synthesis: Although obesity is a public health problem affecting several age groups, it is among children and adolescents that it plays a more important role, due to treatment complexity, high likelihood of persistence into adulthood, and association with other non- transmissible diseases while still in early age. Environment is a main component of the genesis and outcomes in the near future or long term. Modification of intake with high-density food, meal skipping, and high intake of saturated fat, sugar, and salt, associated to high levels of sedentarism are main causes of obesity. Conclusion: Intervention opportunities are related to modifications in political, environmental, and individual settings. School and physical activities in the educational environment are intertwined with nutrition intervention in continuous education. A critical review of some different scenarios in Latin American countries is presented.

  7. Engineering opportunities in cancer immunotherapy.

    Science.gov (United States)

    Jeanbart, Laura; Swartz, Melody A

    2015-11-24

    Immunotherapy has great potential to treat cancer and prevent future relapse by activating the immune system to recognize and kill cancer cells. A variety of strategies are continuing to evolve in the laboratory and in the clinic, including therapeutic noncellular (vector-based or subunit) cancer vaccines, dendritic cell vaccines, engineered T cells, and immune checkpoint blockade. Despite their promise, much more research is needed to understand how and why certain cancers fail to respond to immunotherapy and to predict which therapeutic strategies, or combinations thereof, are most appropriate for each patient. Underlying these challenges are technological needs, including methods to rapidly and thoroughly characterize the immune microenvironment of tumors, predictive tools to screen potential therapies in patient-specific ways, and sensitive, information-rich assays that allow patient monitoring of immune responses, tumor regression, and tumor dissemination during and after therapy. The newly emerging field of immunoengineering is addressing some of these challenges, and there is ample opportunity for engineers to contribute their approaches and tools to further facilitate the clinical translation of immunotherapy. Here we highlight recent technological advances in the diagnosis, therapy, and monitoring of cancer in the context of immunotherapy, as well as ongoing challenges.

  8. OPPORTUNITIES TO PRODUCE HEALTHIER BEEF

    Directory of Open Access Journals (Sweden)

    G. HOLLÓ

    2013-12-01

    Full Text Available In this study the opportunities for enhancing the beneficial fatty acid in beef was examined. The effect of diet (extensive vs. intensive diet, forage to concentrate ratio, feeding concentrates rich in n-3 fatty acids and the breed (old: Hungarian Grey, dual purpose: Hungarian Simmental, dairy: Hungarian Holstein-Friesian was investigated on the fatty acid composition of beef. Findings reveal that the extensive diet with linseed supplemented concentrate influenced the n-6/n-3 ratio and the CLA content of longissimus muscle more advantageous concerning human nutrition. The meat from Hungarian Grey (HG contained more CLA and less n-6 fatty acids than that of Holstein-Friesian bulls. The different forage to concentrate ratio with/without linseed supplementation did not significantly affect the performance and slaughter traits in Hungarian Simmental (HS young bulls. The wider forage to linseed concentrate ratio caused slightly higher dressing percentage, meat and fat proportion and lower bone in carcass. The effect of muscle type on chemical composition of muscles is more significant than that of the diet. SFA and MUFA were affected by muscle type, n-3 fatty acids and n-6/n-3 fatty acid ratio of the diet. The level of cis-9 trans-11 CLA (mg/100 g was influenced by muscle type, but not by diet.

  9. Cooperative Projects - Challenges and Opportunities

    Science.gov (United States)

    Schubotz, Wiebke; Brücher, Tim; Vamborg, Freja

    2017-04-01

    Today's research in Germany is often organized in large projects and collaborations, so-called cooperative projects ("Verbundprojekte" in German). These projects are defined by a large number of members (more than 50) and participating institutes, e.g. institutes of research organizations such as the Max-Planck society and the Leibniz association, Helmholtz centres, and universities. For coordination purposes these projects usually have a general project manager or project coordinator close to the speaker of the project. Despite this overarching position, it is often challenging for the project manager to really overview the entire project as he is, for example, not involved in the individual institute's recruitment processes or research connections to other institutes via other projects. Additionally, there is neither a formal obligation for the principal investigators and project scientists to report changes within their sub-projects, nor any formal dependency between these sub-projects and the coordination office to ensure a contemporary update of changes and progress in their specific tasks of the project. Therefore, the idea of a coordinating position to oversee the entire cooperative project is sometimes difficult to reach. Furthermore, project managers usually have no formal connection to other project managers. This means that recurrent tasks, for which cooperation between project managers would be helpful, need to be reinvented for each project anew. Due to the lack of this more formalized cooperation between project managers, acquired expertise is often lost. We will illustrate the challenges of this kind of project management based on projects at the Max Planck Institute for Meteorology (Hamburg) and the Helmholtz Centre for Ocean Research (GEOMAR, Kiel), but also point out opportunities that arise within a large collaboration of partners. Moreover, we present an approach to coordinate management processes in order to overcome some of the aforementioned

  10. GWAS 2011: Opportunities and challenges

    Institute of Scientific and Technical Information of China (English)

    Jian-Jun Liu; Xue-Jun Zhang

    2011-01-01

    The wide adoption of genome-wide association study (GWAS) has dramatically changed the landscape of the genetic studies of human diseases.Banking on the study design that employs large and multiple-independent samples,linkage disequilibrium (LD) -based systematic genome-wide interrogation,and vigorous statistical standard for declaring genetic association,GWAS has greatly advanced the genetic studies of human disease by successfully identifying over 4 thousands of genetic susceptibility SNPs or loci for 210 diseases/traits in human.Besides its unrivaled scientific achievements,GWAS has also transformed the communities of human genetics by stimulating unprecedented broad and large-scale collaboration and data sharing across different groups and countries,which has enabled some mega genetic studies where dozens or hundreds of thousands of samples were investigated through mete-analysis,providing enormous statistical power for discovering genetic variants,even the ones with very moderate effect on disease phenotype or physiological trait.While the success of GWAS has been widely recognized,there are many concerns on GWAS that are being passionately debated.In particular,there ate heated discussions on why only a limited proportion,quiet often a small proportion,of genetic heritability can be explained by the GWAS findings,and whether and how the GWAS findings have really advanced the biological investigation and understanding of disease mechanisms.Concerning these shortcomings of GWAS,many have genuinely questioned the perspective of translating the GWAS findings into clinical practice.To provide a platform to discuss the progresses and shortcomings of GWAS,a nature conference,titled “GWAS 2011:Opportunities and Challenges”,was organized through the collaboration between the Nature Genetics and Anhui Medical University,which was held in Hefei,China on May 19-21,2011.

  11. Opportunities and challenges for textile reinforced composites

    Science.gov (United States)

    Pastore, Christopher M.

    2000-03-01

    For several decades researchers have been interested in textile processes for the production of composite reinforcement. These technologies have offered several promises: reduced fabrication costs, 3-D multiaxial reinforcement, and damage tolerance. Despite these advantages, textile composites have not reached the level of implementation of laminated composites. In this paper, the opportunities provided by textile reinforced composites and the challenges that limit their implementation will be discussed in detail. Textile composites refer to a family of processes: weaving, braiding, knitting, and hybrids thereof. The various families of textiles will be defined and the basics of fabric formation for each family will be detailed. In particular, the strengths and weaknesses of each manufacturing technique will be addressed to provide a view of the applicability of each technology. This will include some guidance on shape formation capability, property ranges, size limitations, and estimates of cost to produce. Potential applications for these materials will be presented. Among the limitations on the application of textile reinforced composites is the lack of adequate modeling capabilities for these materials. Textile composites have rather large unit cell structures and are highly inhomogeneous throughout their volumes. These features provide benefits in manufacturing, but require novel modeling techniques to correctly understand the mechanical behavior. A review of analytical techniques applied to textile composites will be presented along with a discussion of the benefits and weaknesses of each of these methods. The enabling technologies needed to further the implementation of textile composites in structural applications will be discussed.

  12. Misperception, misfearing, missed treatment, missed opportunities

    Directory of Open Access Journals (Sweden)

    Marcelo Katz

    2014-11-01

    Full Text Available Cardiovascular disease still represents the leading cause of death worldwide. Preventive measures are essential to avoid the burden of disease, saving lives and costs. However, the current prevalence of optimal management of cardiovascular risk factors is far from ideal. In the real world, physicians are not succeeding in convincing their patients to assume healthy behaviors. According to the health belief model theory, if a patient feels he/she is vulnerable to one condition, it enhances the chance that this patient will engage medical recommendations to avoid this condition. However, a couple of articles, evaluating individual perception of risk, show that, in fact, subjects, children and adults, usually have a misperception of risk, with an optimistic bias about their risk. Physicians are missing the opportunity to really prevent the burden of cardiovascular disease and it is time to explore patients' behavior deeply. In the office, physicians should dedicate time to apply in practice the components of the health belief model. If a patient is unaware about his/her actual risk, doctors should detail these risks, graduating severity and anticipating possible implications on the patient's cardiovascular health. Physicians should appraise the accuracy of the patients' perception of own risk and in case of underestimation, work on calibrating this perception. But physicians should go ahead, trying to empower and engage the patient and his/her family into the treatment plan.

  13. Analysis of benefits, opportunities, costs, and risks (BOCR) with the AHP+ANP : A critical validation

    NARCIS (Netherlands)

    Wijnmalen, D.J.D.

    2007-01-01

    This paper shows that the usual multiplicative synthesis of alternative priorities for benefits, opportunities, costs and risks, obtained from separate Analytic Hierarchy or Network models, can be ambiguous. The ratio of benefit and opportunity priorities to cost and risk priorities can be misleadin

  14. Defining Opportunity to Learn for English Language Learners: Linguistic and Cultural Dimensions of ELLs' Instructional Contexts

    Science.gov (United States)

    Aguirre-Munoz, Zenaida; Amabisca, Anastasia A.

    2010-01-01

    Past research demonstrates the critical role of the context of learning in the achievement of students. This body of work justifies research and development of more contextualized opportunity to learn (OTL) models. We expound on an OTL framework that represents contextual features that can enrich or constrain opportunities for English language…

  15. Challenges and Opportunities in Urban Meteorology Research and Forecast

    Institute of Scientific and Technical Information of China (English)

    Wang Yingchun; Wu Dui; Li Ju; Chen Fei; Lenschow Donald; Sun Jielun; Niyogi Dev; Lau Kaihon; Jiang Weimei; Ding Guoan

    2005-01-01

    @@ An international workshop on urban meteorology: observation and modeling, was jointly held by the Institute of Urban Meteorology ( China ) and the National Center for Atmospheric Research (US) in Beijing, October, 2004. The workshop was intended to share recent progress in urban meteorological research, discuss issues related to research and development priorities faced by diverse Chinese institutions, and explore collaboration opportunities between Chinese and US research institutions. This article summarizes the major issues discussed at the workshop, including observation on urban boundary layer, urban landuse modeling, socio-economic impacts of weather and climates, and air quality in urban environment. It includes recommendations for future urban meteorology observational and modeling research, and potential collaborative opportunities between China and US.

  16. Modeling and identification of new complementary development opportunities in a Campos Basin offshore giant field; Modelagem e identificacao de novas oportunidades de desenvolvimento complementar de um campo gigante na Bacia de Campos

    Energy Technology Data Exchange (ETDEWEB)

    Gomes, Jose Adilson T.; Steagall, Daniel E.; Lorenzatto, Rudimar Andreis [PETROBRAS, Rio de Janeiro, RJ (Brazil)

    2004-07-01

    The objective of this paper is to present the methodology that has been used for the complementary development of the giant Marlin oil field in the Campos Basin, with the study of the opportunities of new wells and application of new technologies for the enhancement of production, recovery factor and the gain of reserves. This methodology is applied integrating geophysics, geology, engineering, planning and operation, containing: identification of the non drained areas, positioning of new locations, risk analysis, reduction risk analysis actions, production estimation, attractive location selection; conceptual well project with location of the well head, submarine layout, drilling program, multiphase flow curves; drilling schedule, completion, and production commencement; production forecasting with flux simulation using operational reality of the oil, gas, and water treatment production capacity; wells substitution and deviation criteria; project critical resources and preliminary economical evaluation including project risk. The obtained results were the optimization of the project portfolio of new wells considering the identification of new opportunities, schedule and entrance order of wells, helping also in the acquisitions of new data for reservoir risk reduction before project implementation. (author)

  17. Environmental Modeling, The Buffer Priority layers for Phosphorus / Sediment) Removal identify priority forest/grass buffer opportunities by subwatershed. Land use, hydrology, soil, and landscape characteristics were analyzed to rank buffer opportunities with high P/sed removal., Published in 2014, Smaller than 1:100000 scale, Maryland Department of Natural Resources.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Environmental Modeling dataset, published at Smaller than 1:100000 scale, was produced all or in part from Other information as of 2014. It is described as 'The...

  18. Physics Opportunities at the Next Generation of Precision Flavor Physics

    CERN Document Server

    Ciuchini, Marco

    2011-01-01

    Starting with next-generation experiments, flavor physics fully enters the era of precision measurements. The focus shifts from testing the Standard Model to finding and characterizing new physics contributions. We review the opportunities offered by future flavor experiments, discussing the expected sensitivities of the most important measurements. We also present some examples of measurable deviations from the Standard Model in the flavor sector generated in a selection of new physics models, demonstrating the major contribution that precision flavor physics could give to the effort of going beyond the Standard Model.

  19. 75 FR 10464 - Broadband Technology Opportunities Program

    Science.gov (United States)

    2010-03-08

    ... National Telecommunications and Information Administration RIN 0660-ZA28 Broadband Technology Opportunities... Technology Opportunities Program (BTOP) is extended until 5:00 p.m. Eastern Daylight Time (EDT) on March 26... Sustainable Broadband Adoption (SBA) projects. DATES: All applications for funding CCI projects must...

  20. Putting Opportunism in the Back Seat

    DEFF Research Database (Denmark)

    Foss, Nicolai; Weber, Libby

    2013-01-01

    TCE and its applications in management research put more emphasis on opportunism than on bounded rationality. By augmenting the bounded rationality assumption to include interpretive limitations, we show that there are sources of costly conflict that are not rooted in opportunism. Moreover, we show...

  1. Vocational Education and Equality of Opportunity.

    Science.gov (United States)

    Horowitz, Benjamin; Feinberg, Walter

    1990-01-01

    Examines the concepts of equality of opportunity and equality of educational opportunity and their relationship to vocational education. Traces the history of vocational education. Delineates the distinction between training and education as enumerated in Aristotelian philosophy. Discusses the role vocational education can play in the educative…

  2. Preventive maintenance at opportunities of restricted duration

    NARCIS (Netherlands)

    R. Dekker (Rommert); E. Smeitink

    1994-01-01

    textabstractThis article deals with the problem of setting priorities for the execution of maintenance packages at randomly occurring opportunities. These opportunities are of restricted duration, implying that only a limited number of packages can be executed. The main idea proposed is to set up a

  3. Challenges and Opportunities for Libraries in Pakistan

    OpenAIRE

    Shafiq UR, Rehman; Pervaiz, Ahmad

    2007-01-01

    Abstract: This paper, based on review of literature, observation, and informal conversations, discusses various challenges regarding finance, collection development, ICTs, human resources, library education, library association and research & development faced by library profession in Pakistan. The opportunities to meet these challenges have also been explored. Keywords: Library challenges and opportunities (Pakistan); Librarianship (Pakistan); Library issues; Library profession in Pa...

  4. On Risks and Opportunities in Financial Markets

    NARCIS (Netherlands)

    S.D. Lansdorp (Simon)

    2012-01-01

    textabstractInvesting in financial securities inevitably involves risks on the one hand and opportunities on the other hand. This thesis bundles four different studies on risks and/or opportunities in financial markets. In one study, we examine the cross-sectional explanatory power of different risk

  5. Vegetables Business Opportunities in Ghana: 2014

    NARCIS (Netherlands)

    Saavedra Gonzalez, Y.R.; Dijkxhoorn, Y.; Elings, A.; Glover-Tay, J.; Koomen, I.; Maden, van der E.C.L.J.; Nkansah, G.; Obeng, P.

    2014-01-01

    This report addresses the current performance, overall business climate of the vegetable sector and tries to come up with a number of business opportunities. These include business opportunities for high-quality exports, greenhouse technology, and healthy food for the domestic market. It equally

  6. Opportunists and opportunities: the 2010 SHEA Lecture.

    Science.gov (United States)

    Henderson, David K

    2010-11-01

    My experience as a hospital epidemiologist at the National Institutes of Health Clinical Center has underscored the importance of aggressively managing infection with opportunistic pathogens and of taking advantage of opportunities as they arise (most often as crises). I review selected aspects of my career and use these as examples of the opportunists and opportunities now facing healthcare epidemiology.

  7. Race, Inequality of Opportunity, and School Choice

    Science.gov (United States)

    Darby, Derrick; Saatcioglu, Argun

    2015-01-01

    Both neoliberals and liberals call for mitigating inequality of educational opportunity stemming from circumstances beyond an individual's control. In this article, we challenge the wisdom of making equality of opportunity hinge on emphasizing the distinction rather than the relationship between choices and circumstances. We utilize an empirical…

  8. UAV imagery analysis: challenges and opportunities

    Science.gov (United States)

    Grant, Barbara G.

    2017-05-01

    As UAV imaging continues to expand, so too do the opportunities for improvements in data analysis. These opportunities, in turn, present their own challenges including the need for real time radiometric and spectral calibration; the continued development of quality metrics facilitating exploitation of strategic and tactical imagery; and the need to correct for sensor and platform-induced artifacts in image data.

  9. Vegetables Business Opportunities in Ghana: 2014

    NARCIS (Netherlands)

    Saavedra Gonzalez, Y.R.; Dijkxhoorn, Y.; Elings, A.; Glover-Tay, J.; Koomen, I.; Maden, van der E.C.L.J.; Nkansah, G.; Obeng, P.

    2014-01-01

    This report addresses the current performance, overall business climate of the vegetable sector and tries to come up with a number of business opportunities. These include business opportunities for high-quality exports, greenhouse technology, and healthy food for the domestic market. It equally adv

  10. Index of Economic Freedom: Unrealized Pedagogical Opportunities

    Science.gov (United States)

    Maier, Mark; Miller, John A.

    2017-01-01

    Although the Index of Economic Freedom appears in many economic textbooks, their coverage of the index misses opportunities to teach statistical and policy-related concepts important for the principles course. The standard textbook presentation passes up an opportunity to examine the statistical issues of weighting in composite index numbers and…

  11. Crisis/Opportunity: 2011 WICHE Workplan

    Science.gov (United States)

    Western Interstate Commission for Higher Education, 2010

    2010-01-01

    Public higher education has faced a crisis of massive proportions in the first decade of this millennium. Nevertheless, for higher education, this year represents a turning point and, yes, an opportunity. The opportunity, then, for the West is one that generations of Americans are familiar with: to do more with less. Dealing with scarcity--whether…

  12. 47 CFR 73.1941 - Equal opportunities.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Equal opportunities. 73.1941 Section 73.1941... Rules Applicable to All Broadcast Stations § 73.1941 Equal opportunities. (a) General requirements...-spot coverage of bona fide news events (including, but not limited to political conventions...

  13. Consumerism as a branding opportunity.

    Science.gov (United States)

    Treash, M; Adams, R

    1998-01-01

    Managing a customer portfolio at the individual level is the most difficult and most promising endeavor. An individual level consumer portfolio does not mean creating marketing materials and advertising campaigns customized for every member of your health plan. What it does mean is developing segmentation models based on consumer preferences extracted directly from your members, not socioeconomic or other demographic models. The most important information to extract is perceptions on how much and what kind of value members want from the organization.

  14. Opportunity for Whom?: Political Opportunity and Critical Events in Canadian Aboriginal Mobilization, 1951-2000

    Science.gov (United States)

    Ramos, Howard

    2008-01-01

    Many social movement researchers question the usefulness of political opportunity as a concept. However, others argue that it can be refined by disaggregating different opportunities for actors and outcomes to understand the underlying mechanisms that influence each. This research extends this analysis by asking "political opportunity for…

  15. Opportunity for Whom?: Political Opportunity and Critical Events in Canadian Aboriginal Mobilization, 1951-2000

    Science.gov (United States)

    Ramos, Howard

    2008-01-01

    Many social movement researchers question the usefulness of political opportunity as a concept. However, others argue that it can be refined by disaggregating different opportunities for actors and outcomes to understand the underlying mechanisms that influence each. This research extends this analysis by asking "political opportunity for…

  16. Opportunities for Funding at NSF

    Science.gov (United States)

    Kafafi, Zakya H.

    2009-03-01

    Materials science, inter- and multi-disciplinary in nature, provides the bridge to many areas of fundamental and applied sciences such as biology, chemistry, physics, mathematics, computer sciences, and engineering. Strong links that may exist between materials science and other disciplines, such as biology or chemistry or physics, very often lead to novel applications and enable technologies of great benefit to our society. The Division of Materials Research (DMR) invested 274.0 M in FY 2008 and is estimated to invest 324.6 M in FY 2009 funding research and education as well as enabling tools & instrumentation for individual investigators, groups, centers, and national facilities. DMR programs cover a wide spectrum of materials research and education ranging from condensed matter and materials physics, solid-state and materials chemistry, multifunctional, hybrid, electronic, photonic, metallic, ceramic, polymeric, bio-materials, composites and nanostructures to list a few. New modes of funding, research opportunities and directions, such as the recent SOLAR solicitation, will be described. This Solar Energy Initiative launched jointly by three divisions, namely Chemistry, Materials Research and Mathematical Science is aimed at supporting truly interdisciplinary efforts that address the scientific challenges of highly efficient harvesting, conversion, and storage of solar energy. The goal of this new program is to create a new modality of linking the mathematical with the chemical and materials sciences to develop transformative paradigms based on the integrated expertise and synergy from three disciplinary communities. DMR is also seeking new ways to transform materials science and education, and make it more attractive as a career for bright, young women & men. A description will be given of several workshops held this year and planned for next year with this purpose in mind. Outreach programs that emphasize how the innovations resulting from materials research

  17. Wildfire Risk Management: Challenges and Opportunities

    Science.gov (United States)

    Thompson, M.; Calkin, D. E.; Hand, M. S.; Kreitler, J.

    2014-12-01

    In this presentation we address federal wildfire risk management largely through the lens of economics, targeting questions related to costs, effectiveness, efficiency, and tradeoffs. Beyond risks to resources and assets such as wildlife habitat, watersheds, and homes, wildfires present financial risk and budgetary instability for federal wildfire management agencies due to highly variable annual suppression costs. Despite its variability, the costs of wildfire management have continued to escalate and account for an ever-growing share of overall agency budgets, compromising abilities to attain other objectives related to forest health, recreation, timber management, etc. Trends associated with a changing climate and human expansion into fire-prone areas could lead to additional suppression costs in the future, only further highlighting the need for an ability to evaluate economic tradeoffs in investments across the wildfire management spectrum. Critically, these economic analyses need to accurately capture the complex spatial and stochastic aspects of wildfire, the inherent uncertainty associated with monetizing environmental impacts of wildfire, the costs and effectiveness of alternative management policies, and linkages between pre-fire investments and active incident management. Investing in hazardous fuels reduction and forest restoration in particular is a major policy lever for pre-fire risk mitigation, and will be a primary focus of our presentation. Evaluating alternative fuel management and suppression policies could provide opportunities for significant efficiency improvements in the development of risk-informed management fire management strategies. Better understanding tradeoffs of fire impacts and costs can help inform policy questions such as how much of the landscape to treat and how to balance investments in treating new areas versus maintaining previous investments. We will summarize current data needs, knowledge gaps, and other factors

  18. Learning Opportunities for Group Learning

    Science.gov (United States)

    Gil, Alfonso J.; Mataveli, Mara

    2017-01-01

    Purpose: This paper aims to analyse the impact of organizational learning culture and learning facilitators in group learning. Design/methodology/approach: This study was conducted using a survey method applied to a statistically representative sample of employees from Rioja wine companies in Spain. A model was tested using a structural equation…

  19. Learning Opportunities for Group Learning

    Science.gov (United States)

    Gil, Alfonso J.; Mataveli, Mara

    2017-01-01

    Purpose: This paper aims to analyse the impact of organizational learning culture and learning facilitators in group learning. Design/methodology/approach: This study was conducted using a survey method applied to a statistically representative sample of employees from Rioja wine companies in Spain. A model was tested using a structural equation…

  20. Research opportunities in muscle atrophy

    Science.gov (United States)

    Herbison, G. J. (Editor); Talbot, J. M. (Editor)

    1984-01-01

    Muscle atrophy in a weightless environment is studied. Topics of investigation include physiological factors of muscle atrophy in space flight, biochemistry, countermeasures, modelling of atrophied muscle tissue, and various methods of measurement of muscle strength and endurance. A review of the current literature and suggestions for future research are included.

  1. IPRs in biobanking- risks and opportunities for translational research

    DEFF Research Database (Denmark)

    Minssen, Timo; Verlinden, Michiel; Huys, Isabelle

    2015-01-01

    The gradual shift from traditional closed innovation systems to more “open” and “transparent” innovation models, rapid technological advances and bio-pharmaceutical innovation gaps have highlighted the importance of an effective governance and use of biobanks. This raises important legal questions...... an overview and analysis of the most relevant IPRs in biobanking and to discuss the challenges and opportunities associated with an effective use of biobanks in translational research and innovation. Section 1 specifies challenges in finding a balance between an open and a close collaboration model. Section 2...... such as how to deal with intellectual property rights (‘IPRs’) that might arise out of the collection and use of samples and data in research. Only a few projects highlighted the opportunities and potential benefits of user-generated solutions and proper governance of IPRs. This paper aims to provide...

  2. Natural gas vehicles : Status, barriers, and opportunities.

    Energy Technology Data Exchange (ETDEWEB)

    Rood Werpy, M.; Santini, D.; Burnham, A.; Mintz, M.; Energy Systems

    2010-11-29

    In the United States, recent shale gas discoveries have generated renewed interest in using natural gas as a vehicular fuel, primarily in fleet applications, while outside the United States, natural gas vehicle use has expanded significantly in the past decade. In this report for the U.S. Department of Energy's Clean Cities Program - a public-private partnership that advances the energy, economic, and environmental security of the U.S. by supporting local decisions that reduce petroleum use in the transportation sector - we have examined the state of natural gas vehicle technology, current market status, energy and environmental benefits, implications regarding advancements in European natural gas vehicle technologies, research and development efforts, and current market barriers and opportunities for greater market penetration. The authors contend that commercial intracity trucks are a prime area for advancement of this fuel. Therefore, we examined an aggressive future market penetration of natural gas heavy-duty vehicles that could be seen as a long-term goal. Under this scenario using Energy Information Administration projections and GREET life-cycle modeling of U.S. on-road heavy-duty use, natural gas vehicles would reduce petroleum consumption by approximately 1.2 million barrels of oil per day, while another 400,000 barrels of oil per day reduction could be achieved with significant use of natural gas off-road vehicles. This scenario would reduce daily oil consumption in the United States by about 8%.

  3. Organizational Actively Management for Opportunity Hunting

    Directory of Open Access Journals (Sweden)

    Nasser Fegh-hi FARAHMAND

    2012-03-01

    Full Text Available Organizational Actively Management (OAM is the responsibility of every manager. Because, an approach for OAM is becoming more widely accepted is a community-based development approach. In Opportunity Hunting Approach (OHA, OAM is the responsibility of every manager for his/her actions. OAM is using from top to bottom development model. According to the survey of market and customers, after understand customers’ needs, organization then decide how the quality policy and target will develop, from there the actively management system can be developed. The aim of this study in field of organizational actively management and policy of it can provide the specific process required for setting up and monitoring the actively target. As it also is customer-oriented, it aims to improve customer satisfaction. In addition, the actively target should be set up and implemented within every organization department and at each level, in accordance with actively policy. Furthermore, organization should develop the actively management system, in order to conform to general requirements and actively target.

  4. Revenue generation in the information era: Opportunities and challenges

    Directory of Open Access Journals (Sweden)

    Sreelata Jonnalagedda

    2011-03-01

    Full Text Available In an information economy, innovative revenue generating models are as critical for the sustenance of a firm as is bringing cutting edge technology to the market. In its first part, this article surveys the characteristics of the information goods market and identifies the opportunities and challenges that the information era presents. Further, it surveys the existing business models for information goods and maps them to the market characteristics to arrive at the viability of these models. The second part of the article presents the views and experiences of a panel of practitioners who face these challenges in the field of information goods.

  5. Environmental challenges and opportunities of the evolving North American electricity market : Modeling techniques and estimating environmental outcomes[Secretariat report to Council under article 13 of the North American agreement on environmental cooperation

    Energy Technology Data Exchange (ETDEWEB)

    Patterson, Z. [Commission for Environmental Cooperation of North America, Montreal, PQ (Canada)

    2002-06-01

    Background information and results of the different models publicly available used for the evaluation of environmental effects of electricity market restructuring in the various jurisdictions in North America were included in this working paper. It comprised the description of eleven models and twelve modeling exercises. The information on each model varied greatly, as it is proprietary. The models described were: (1) the Energy Information Administration's (EIA) National Energy Modeling System (NEMS), (2) the Department of Energy's Policy Office Electricity Modeling System (POEMS), (3) the Integrated Planning Model (IPM) utilized by the United States Environmental Protection Agency (US EPA), (4) Resources for the Future's (RFF) Haiku model, (5) the Canadian Energy Research Institute's Energy 2020 Model, (6) the Federal Energy Regulatory Commission's (FERC) use of ICF's Coal and Electric Utilities Model, (7) the Center for Clean Air Policy's use of General Electric's Market Assessment and Portfolio Strategies (GE MAPS) model, (8) the Center for Clean Air Policy's use of GE MAPS in combination with New Energy Associates' Proscreen II, (9) the Commission for Environmental Cooperation use of the Front of Envelope Model, (10) Ontario Power Generation's use of the Utility Fuel Economics Model and National Power Model, and (11) New York State Department of Public Service's (NYDPS) Final Generic Environmental Impact Statement using New Energy Associates' PROMOD. Also included in this working paper was a comparison of the results of models and modeling exercises on which the estimation of the environmental effects of electricity market restructuring in the United States was based. 18 refs., 5 tabs.

  6. Opportunities for green growth; Vihreaen kasvun mahdollisuudet

    Energy Technology Data Exchange (ETDEWEB)

    Antikainen, R.; Mickwitz, P.; Seppaelae, J. [and others

    2013-03-15

    The report seeks an answer to the question as to the kind of policy decisions (steps) by which preconditions for green growth may be created in Finland. The proposed steps are based on a review of earlier research and studies relating to Finland's key consumption and production systems (food, housing, transport and energy) and to certain path finding countries in terms of the green economy (the Netherlands, Germany, Sweden, Brazil). In addition, the report examines various models by which systemic change towards a green economy may be supported. The report also highlights successful examples of green business activity and measures to promote green growth. Green Growth is defined as low-carbon, resource-efficient economic growth based on safeguarding the functional capacity of ecosystems while promoting wellbeing and social justice. Green growth is considered to have significant worldwide potential, which is currently evident particularly in the rapid growth of cleantech demand. Successful future actors will be more material- and energy-efficient than their competitors, and they will be able to provide services and products flexibly for a low-carbon society. There are opportunities for green growth in all sectors of society. Green growth may consist of an entirely new kind of business activity and create new companies, but there are also opportunities in our traditional energy- and resource-intensive industries. Companies have a key role in growth, but realising green growth also requires changes in consumption. Central, regional and local government will act as facilitators in creating the preconditions for green growth. The report presents a number of policy measures and processes by which Finland can support green growth. Proposals for steps towards green growth include: (A.) Creating preconditions for green growth through a joint vision and political commitment. (B.) Stimulating companies' green growth potential and boosting green demand. (C

  7. EQUAL OPPORTUNITIES IN THE ITALIAN LABOUR MARKET

    Directory of Open Access Journals (Sweden)

    Balazs-Foldi Emese

    2015-07-01

    Full Text Available The integration of persons with disabilities and with reduced work capacity in the labour market represents one of the biggest challenges for labour market policies. The non-integration of disabled people in the labour market causes huge costs for the countries’ economy. The European Union’s aim is to transform passive social support into active support by means of labor market policy measures, to help people to obtain gainful employment and to raise employment levels of people with disabilities and with reduced work capacities. Earlier this target group has to work in the sheltered employment. But it changed from the 90’s years because of the social model of disability definition. Nowadays the main goal to help this target group integrates in the open employment. The members of European Union imagine this aim on other way. The Scandinavian countries or England prefer the equal opportunities and the personalised mainstreaming programmes and services. Other European countries, as Germany, Austria or Italy prefer the rehabilitation quota system. Thus, the labor force participation and employment rates for people with disabilities and with reduced working capacities are strong differences between the European countries. But lot of other options also influence the member of countries’ policy and employment system. Since the Amsterdam Treaty the European Union has devoted exceptional attention to the equal opportunities of disabled people, the enforcement of equal treatment, and the reduction of the dangers of discrimination, as it is, a significant part of persons with disabilities and reduced work capacity do not have a full-time job, they become unemployed two or three times more frequently than their abled-counterparts, and dispose of lower salary, therefore they need the help of their family and the community. This study examines the Italian situation. It bases on statistics on the Italian target group and provides comparisons with

  8. 2015 Veteran Economic Opportunity Report

    Science.gov (United States)

    2015-01-01

    and data analysis to the VBA and stakeholders. PA&I developed the VBA Enterprise Data Warehouse to enable the generation of recurring and ad hoc...reports in response to VBA decision-making and business needs. PA&I will be a primary source of information on Veteran education, vocational...competitiveness from preliminary analyses pre- sented in this document. 4. Build predictive models through analysis of individual-level stakeholder data on Veteran

  9. USAJOBS Job Opportunity Announcements (JOA) SOAP API

    Data.gov (United States)

    Office of Personnel Management — The purpose of the SOAP based API is to provide the full Federal Job Opportunity Announcement (JOA) content to the consumer. It is anticipated that this API will be...

  10. Technological opportunities and paths of development

    DEFF Research Database (Denmark)

    Plichta, Kirsten

    1993-01-01

    in the industry. 6) It is argued that such paths of incremental improvement at the industry level may be an outcome of a) the dynamics that produce the technological opportunities; b) the institutions that govern decisions and expectations and c) the criteria by which the chooses between different firms......Executive summary: 1) The technological development of firms in an industry is influenced by the opportunities for improving product and process, their ability to identify such opportunities and their ability to appropriate the benefit of the development effort. 2) Firms' historically developed...... technological knowledge, their production, development and other routines as well prior investments in products and production equipment play an important role with regard to the technological opportunities that firms' identify and select for development. 3) Because history matters and because firms are bounded...

  11. Chinese M&A,Opportunities & Risks

    Institute of Scientific and Technical Information of China (English)

    Tang Jintao

    2009-01-01

    @@ Recently, the cases of Chinese enterprises' merger and acquisition are emerging in multitude. It is believed that M&A will provide opportunities for China enterprises to go global and act in the global economic environment.

  12. Sport Opportunities for Athletes with Disabilities.

    Science.gov (United States)

    Journal of Physical Education, Recreation & Dance, 1984

    1984-01-01

    This series outlines sport opportunities for athletes with disabilities. Included are articles discussing sports for athletes with cerebral palsy, deaf athletes, blind athletes, wheelchair bound athletes, amputee athletes, as well as a discussion of the Special Olympics. (JMK)

  13. Marketing African Leafy Vegetables: Challenges and Opportunities ...

    African Journals Online (AJOL)

    Marketing African Leafy Vegetables: Challenges and Opportunities in the ... especially in the hitherto, non-consuming segments of the society including the upper ... resources could be exploited to their disadvantage is very much a possibility.

  14. Rewards and Opportunities for Successful Entrepreneurs.

    Science.gov (United States)

    Longenecker, Justin G.

    1983-01-01

    Among the rewards for entrepreneurs are money, independence, and a satisfying way of life. A variety of opportunities exist for those with the vision, ingenuity, and courage to exploit the potential of the market place. (SK)

  15. Opportunities for silvicultural treatment in western Oregon.

    Science.gov (United States)

    Colin D. MacLean

    1980-01-01

    A recent Forest Survey inventory of western Oregon has been analyzed to determine the extent of physical opportunities to increase wood production through silvicultural treatment. Results are presented by owner group and by geographic unit.

  16. Flight Opportunities: Space Technology Mission Directorate

    Science.gov (United States)

    Van Dijk, Alexander

    2016-01-01

    Flight Opportunities enables maturation of new space technologies by funding access to commercially available space-relevant test environments. The program also supports capability development in the commercial suborbital and orbital small satellite launcher markets.

  17. Security with Privacy - Opportunities and Challenges

    OpenAIRE

    Bertino, Elisa

    2014-01-01

    This paper summarizes opportunities and challenges concerning how we can achieve security while still ensuring privacy. It identifies research directions and includes a number of questions that have been debated by the panel.

  18. Preamble to marine microbiology: Facets and opportunities

    Digital Repository Service at National Institute of Oceanography (India)

    Ramaiah, N.

    The book titled 'Marine Microbiology: Facets & Opportunities' is an attempt to bring together some facets of marine microbiology as have been made out by many contemporaries in particular from the tropical marine regions. There are 18 contributed...

  19. Water Technology Innovation: Ten Market Opportunities

    Science.gov (United States)

    The Water Technology Innovation Blueprint offers an overview of market opportunities that include conserving and recovering energy, recovering nutrients, improving water infrastructure, reducing costs for water monitoring, and improving water quality.

  20. Internships, employment opportunities, and research grants

    Science.gov (United States)

    ,

    2015-01-01

    As an unbiased, multidisciplinary science organization, the U.S. Geological Survey (USGS) is dedicated to the timely, relevant, and impartial study of the health of our ecosystems and environment, our natural resources, the impacts of climate and land-use change, and the natural hazards that threaten us. Opportunities for undergraduate and graduate students and faculty to participate in USGS science are available in the selected programs described below. Please note: U.S. citizenship is required for all government positions.This publication has been superseded by USGS General Information Product 165 Grant Opportunities for Academic Research and Training and USGS General Information Product 166 Student and Recent Graduate Employment Opportunities.This publication is proceeded by USGS General Information Product 80 Internships, Employment Opportunities, and Research Grants published in 2008.

  1. USAJOBS Job Opportunity Announcements (JOA) REST API

    Data.gov (United States)

    Office of Personnel Management — This REST-based API is designed to support lightweight Federal Job Opportunity Announcement (JOA) content consumption by consumers. It is anticipated that this API...

  2. Industrial Development Opportunity & Trend of Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    Wang YiTao

    2001-01-01

    @@ While having a great development opportunity, CM faces a great marketing competition when entering to WTO. An important change will take place in CM technology, industry as well as overseas and domestic marketing. The domestic CM industry and marketing tend to be "internationalized” while the foreign herbal and traditional drugs tend to be "CM”. This article aims to explore the opportunity, trend and future of CM by analyzing the present status of CM technology, industry and marketing.

  3. Industrial Development Opportunity & Trend of Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    Wang; YiTao

    2001-01-01

    While having a great development opportunity, CM faces a great marketing competition when entering to WTO. An important change will take place in CM technology, industry as well as overseas and domestic marketing. The domestic CM industry and marketing tend to be "internationalized” while the foreign herbal and traditional drugs tend to be "CM”. This article aims to explore the opportunity, trend and future of CM by analyzing the present status of CM technology, industry and marketing.  ……

  4. Summary of the Physics Opportunities Working Group

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Pisin (Stanford Linear Accelerator Center, Menlo Park, CA (United States)); McDonald, K.T. (Princeton Univ., NJ (United States). Joseph Henry Labs.)

    1992-12-01

    The Physics Opportunities Working Group was convened with the rather general mandate to explore physic opportunities that may arise as new accelerator technologies and facilities come into play. Five topics were considered during the workshop: QED at critical field strength, novel positron sources, crystal accelerators, suppression of beamstrahlung, and muon colliders. Of particular interest was the sense that a high energy muon collider might be technically feasible and certainly deserves serious study.

  5. Telecommunications: Opportunities in the emerging technologies

    Energy Technology Data Exchange (ETDEWEB)

    Schultheis, R.W. [Mission Telecommunications Group, Charlottesville, VA (United States)

    1994-12-31

    A series of slides present opportunities for Utility Telecommunications. The following aspects are covered: (1) Technology in a period of revolution; (2) Technology Management by the Energy Utility, (3) Contemporary Telecommunication Network Architectures, (4) Opportunity Management, (5) Strategic Planning for Profits and Growth, (6) Energy Industry in a period of challenge. Management topics and applications are presented in a matrix for generation, transmission, distribution, customer service and new business revenue growth subjects.

  6. Regenerative Medicine-Opportunities and Challenges

    Institute of Scientific and Technical Information of China (English)

    Zhengguo Wang

    2006-01-01

    In this paper, the definitions and contents of regenerative medicine, including tissue engineering, cell therapy, cytokine therapy and microecologic cure, were presented. And then, the prospects and difficulties for clinical application of these therapies were further mentioned. It indicated that the regenerative medicine came to a new era with full of opportunities and challenges. To face and seize this evanescent opportunity is worthy of detailed discussions.

  7. Smart textiles: Challenges and opportunities

    Science.gov (United States)

    Cherenack, Kunigunde; van Pieterson, Liesbeth

    2012-11-01

    Smart textiles research represents a new model for generating creative and novel solutions for integrating electronics into unusual environments and will result in new discoveries that push the boundaries of science forward. A key driver for smart textiles research is the fact that both textile and electronics fabrication processes are capable of functionalizing large-area surfaces at very high speeds. In this article we review the history of smart textiles development, introducing the main trends and technological challenges faced in this field. Then, we identify key challenges that are the focus of ongoing research. We then proceed to discuss fundamentals of smart textiles: textile fabrication methods and textile interconnect lines, textile sensor, and output device components and integration of commercial components into textile architectures. Next we discuss representative smart textile systems and finally provide our outlook over the field and a prediction for the future.

  8. Biomedical wellness challenges and opportunities

    Science.gov (United States)

    Tangney, John F.

    2012-06-01

    The mission of ONR's Human and Bioengineered Systems Division is to direct, plan, foster, and encourage Science and Technology in cognitive science, computational neuroscience, bioscience and bio-mimetic technology, social/organizational science, training, human factors, and decision making as related to future Naval needs. This paper highlights current programs that contribute to future biomedical wellness needs in context of humanitarian assistance and disaster relief. ONR supports fundamental research and related technology demonstrations in several related areas, including biometrics and human activity recognition; cognitive sciences; computational neurosciences and bio-robotics; human factors, organizational design and decision research; social, cultural and behavioral modeling; and training, education and human performance. In context of a possible future with automated casualty evacuation, elements of current science and technology programs are illustrated.

  9. Social Economy: Challenges and Opportunities

    Directory of Open Access Journals (Sweden)

    Ioan HOSU

    2012-06-01

    Full Text Available The present article addresses a topic of interest for both the public sector and the nonprofit sector, namely that of the innovative practices of social economy. Diverse practices and models of social economy are increasingly present in the Romanian community, this being the reason why it is important to study the major coordinates of social economy and social entrepreneurship identified by means of an empirical research done in Romania. Social economy is considered one of the most important innovative strategy approaches as this sector may contribute to some efforts done for the elimination of poverty and the re-launching of local economies. The integration of the identified elements in regional programs and public policies is the starting point of the strategic approaches regarding reform in public administration. Social economy can be an example of joint action for public and private organizations and institutions interested in carrying out community projects based on inclusive, participative and innovative forms of community development.

  10. Entrepreneurship as a Social Journey of Opportunity Construction

    DEFF Research Database (Denmark)

    Sørensen, Suna; Lassen, Astrid Heidemann

    2004-01-01

    the significance of the creative individuals and their interactions, and thereby do not create a foundation close-to-reality for further development of entrepreneurship. Stages models view on the entrepreneurial change process is in the article associated with a ?Pre-defined Journey?, where as the contingency...... models view is linked to a ?Semi-structured Journey?. We introduce an alternative complementary perspective, being Symbolic Interactionism, from which the idea of entrepreneurship as a ?Social Journey of Opportunity Construction? arises. This introduction results in the proposal that we as researchers...

  11. Identity-Based Motivation: Constraints and Opportunities in Consumer Research

    Science.gov (United States)

    Shavitt, Sharon; Torelli, Carlos J.; Wong, Jimmy

    2009-01-01

    This commentary underscores the integrative nature of the identity-based motivation model (Oyserman, 2009). We situate the model within existing literatures in psychology and consumer behavior, and illustrate its novel elements with research examples. Special attention is devoted to, 1) how product- and brand-based affordances constrain identity-based motivation processes and, 2) the mindsets and action tendencies that can be triggered by specific cultural identities in pursuit of consumer goals. Future opportunities are suggested for researching the antecedents of product meanings and relevant identities. PMID:20161045

  12. 78 FR 65608 - Information Collection; Outreach Opportunity Questionnaire

    Science.gov (United States)

    2013-11-01

    ... Forest Service Information Collection; Outreach Opportunity Questionnaire AGENCY: Forest Service, USDA... with revision of a currently approved information collection, Outreach Opportunity Questionnaire. DATES... INFORMATION: Title: Outreach Opportunity Questionnaire. OMB Number: 0596-0207. Expiration Date of...

  13. 75 FR 30364 - Information Collection; Outreach Opportunity Questionnaire

    Science.gov (United States)

    2010-06-01

    ...; ] DEPARTMENT OF AGRICULTURE Forest Service Information Collection; Outreach Opportunity Questionnaire AGENCY... Opportunity Questionnaire. DATES: Comments must be received in writing on or before August 2, 2010 to be... Friday. SUPPLEMENTARY INFORMATION: Title: Outreach Opportunity Questionnaire. OMB Number:...

  14. Directive deficiencies: How resource constraints direct opportunity identification in SMEs

    NARCIS (Netherlands)

    Burg, van J.C.; Podoynitsyna, K.S.; Beck, Lien; Lommelen, T.

    2012-01-01

    Previous studies show that resource constraints have mixed effects on innovation and opportunity identification by entrepreneurs. Sometimes, resource constraints lead to identifying more opportunities, whereas in other cases entrepreneurs rather see fewer opportunities. This study explores a new

  15. More Opportunities than Wealth: A Network of Power and Frustration

    CERN Document Server

    Mahault, Benoit; Nisoli, Cristiano

    2015-01-01

    We introduce a minimal agent-based model to qualitatively conceptualize the allocation of limited wealth among more abundant opportunities. We study the interplay of power, satisfaction and frustration in distribution, concentration, and inequality of wealth. Our framework allows us to compare subjective measures of frustration and satisfaction to collective measures of fairness in wealth distribution, such as the Lorenz curve and the Gini index. We find that a completely libertarian, law-of-the-jungle setting, where every agent can acquire wealth from, or lose wealth to, anybody else invariably leads to a complete polarization of the distribution of wealth vs. opportunity. The picture is however dramatically modified when hard constraints are imposed over agents, and they are limited to share wealth with neighbors on a network. We then propose an out of equilibrium dynamics {\\it of} the networks, based on a competition between power and frustration in the decision-making of agents that leads to network coevo...

  16. Doctor of Nursing Practice programs: opportunities for faculty development.

    Science.gov (United States)

    Sebastian, Juliann G; White Delaney, Connie

    2013-08-01

    This article examines development opportunities for faculty teaching in Doctor of Nursing Practice (DNP) programs. Although faculty development for DNP programs is similar to that of other academic programs, faculty may need different strategies for teaching, scholarship, and service because DNP programs focus on translation of science into practice, systems-level changes, clinical scholarship, and the highest levels of advanced nursing practice. Faculty and student collaboration across DNP and PhD programs provide new approaches for translating research into practice and generating practice questions in need of further scientific development. Specific faculty development strategies for facilitating this collaboration are essential. Capstone projects pose special opportunities for faculty development due to the integration of these projects within diverse practice environments, with differing expectations, regulations, and pacing compared with research. Linking new care delivery models with health informatics is expected to facilitate rapid translation of research and development of improvements in practice. Copyright 2013, SLACK Incorporated.

  17. Private Benefits of Control,Growth Opportunities and Investor Protection

    Institute of Scientific and Technical Information of China (English)

    Min Xiao; Jiaxing You

    2009-01-01

    We develop a model to illustrate that controlling shareholders choose the level of investor protection that maximizes their own interests. Controlling shareholders in companies with complicated control structures can easily extract private benefits and are thus reluctant to enhance investor protection which would necessitate increased transparency. In contrast, controlling shareholders in companies with valuable growth opportunities are willing to improve investor protection so that they can benefit from the increased value resulting from the lower cost of capital. We test this prediction using firm-level data in China. The results show that the level of investor protection increases with decreases in control structure opacity and increases in growth opportunities. The correlation is more significant for enforcement than for the mechanisms of investor protection.

  18. Retrieval opportunities while multitasking improve name recall.

    Science.gov (United States)

    Helder, Elizabeth; Shaughnessy, John J

    2008-11-01

    In two experiments we tested whether providing retrieval opportunities while people were multitasking would improve memory for names. College students (n=195) in Experiment 1 did addition problems and intermittently were "introduced" to 12 face-name pairs to learn. For half the names students were given three within-list retrieval opportunities. Name recall (cued with the faces) was tested either immediately or after 24 hours. Retrieval opportunities improved name recall with both immediate and delayed tests. Experiment 2 more closely resembled the multitasking required in a real-life social situation. College students (n=98) viewed a videotape and were asked to learn the names of 12 dormitory residents who were introduced during an ongoing conversation. Retrieval opportunities were provided for 8 of the 12 residents by having them appear three additional times in the video without repeating their names. Retrieval opportunities improved name recall, but the effect was much smaller than in Experiment 1. The present research demonstrates that distributed retrieval can be effective when people are multitasking including when the multitasking involves a conversation.

  19. Overview of energy-conservation research opportunities

    Energy Technology Data Exchange (ETDEWEB)

    Hopp, W.J.; Hauser, S.G.; Hane, G.J.; Gurwell, W.E.; Bird, S.P.; Cliff, W.C.; Williford, R.E.; Williams, T.A.; Ashton, W.B.

    1981-12-01

    This document is a study of research opportunities that are important to developing advanced technologies for efficient energy use. The study's purpose is to describe a wide array of attractive technical areas from which specific research and development programs could be implemented. Research areas are presented for potential application in each of the major end-use sectors. The study develops and applies a systematic approach to identifying and screening applied energy conservation research opportunities. To broadly cover the energy end-use sectors, this study develops useful information relating to the areas where federally-funded applied research will most likely play an important role in promoting energy conservation. This study is not designed to produce a detailed agenda of specific recommended research activities. The general information presented allows uniform comparisons of disparate research areas and as such provides the basis for formulating a cost-effective, comprehensive federal-applied energy conservation research strategy. Chapter 2 discusses the various methodologies that have been used in the past to identify research opportunities and details the approach used here. In Chapters 3, 4, and 5 the methodology is applied to the buildings, transportation, and industrial end-use sectors and the opportunities for applied research in these sectors are discussed.Chapter 6 synthesizes the results of the previous three chapters to give a comprehensive picture of applied energy conservation research opportunities across all end-use sectors and presents the conclusions to the report.

  20. Cultural Differences in Opportunity Cost Consideration

    Science.gov (United States)

    Zhang, Ning; Ji, Li-Jun; Li, Ye

    2017-01-01

    Two studies were conducted to investigate cultural differences in opportunity cost consideration between Chinese and Euro-Canadians. Opportunity cost is defined as the cost of a benefit that must be forgone in order to pursue a better alternative (Becker et al., 1974). In both studies, participants read about hypothetical purchase scenarios, and then decided whether they would buy a certain product. Opportunity cost consideration was measured in two ways: (1) participants' thoughts pertaining to other (nonfocal) products while making decisions; (2) participants' decisions not to buy a focal product (Study 1) or a more expensive product (Study 2). Across both indexes, we found that after controlling for individual difference variables and amount of pocket money, Chinese participants in China considered financial opportunity cost more than Euro-Canadians in Study 1. Similar results were observed in Study 2 when comparing Chinese in Canada with Euro-Canadians However, the cultural effect on opportunity cost consideration was confounded by family income in Study 2. Implications for resource management, limitations of the current research and directions for future research are discussed. PMID:28184202

  1. Cultural Differences in Opportunity Cost Consideration.

    Science.gov (United States)

    Zhang, Ning; Ji, Li-Jun; Li, Ye

    2017-01-01

    Two studies were conducted to investigate cultural differences in opportunity cost consideration between Chinese and Euro-Canadians. Opportunity cost is defined as the cost of a benefit that must be forgone in order to pursue a better alternative (Becker et al., 1974). In both studies, participants read about hypothetical purchase scenarios, and then decided whether they would buy a certain product. Opportunity cost consideration was measured in two ways: (1) participants' thoughts pertaining to other (nonfocal) products while making decisions; (2) participants' decisions not to buy a focal product (Study 1) or a more expensive product (Study 2). Across both indexes, we found that after controlling for individual difference variables and amount of pocket money, Chinese participants in China considered financial opportunity cost more than Euro-Canadians in Study 1. Similar results were observed in Study 2 when comparing Chinese in Canada with Euro-Canadians However, the cultural effect on opportunity cost consideration was confounded by family income in Study 2. Implications for resource management, limitations of the current research and directions for future research are discussed.

  2. Partner Market Opportunities and Relationship Stability

    Directory of Open Access Journals (Sweden)

    Ingmar Rapp

    2015-10-01

    Full Text Available Although partner market opportunities are generally considered to be important for relationship stability, they have never been measured accurately. In order to be able to test the anticipated effects of partner market opportunities, this study conceptualises them as individual opportunities for contact and interaction in concrete social contexts, like the neighbourhood, the workplace, leisure activities, etc. Using data from the German Marriage Market Survey, we first examine the impact of individual partner market opportunities on the risk of separation. Second, we examine to what extend the most frequently studied determinants of divorce and separation depend on partner market opportunities. Our results show that the number of opposite sex contacts increases the probability of separation. Sharing the same contacts with one’s partner decreases the risk of separation. Our results indicate further that reducing opposite sex contacts in the course of the relationship is partly responsible for the higher stability of longer-lasting relationships. Having a migration background is associated with fewer opposite sex contacts. This means that having a migration background would be more destabilising if these individuals did not have less opposite sex contacts than individuals without a migration background. In contrast, joint home ownership, church attendance, higher education and residing in western Germany would generally be more stabilising if these factors were not connected with more opposite sex contacts.

  3. Oportunidade de produção de aço em Mato Grosso do Sul Regional production of steel: an economic model for a business opportunity in Mato Grosso do Sul, Brazil

    Directory of Open Access Journals (Sweden)

    João Orlando Rodrigues de Menezes

    2007-09-01

    Full Text Available Por que buscar, para a produção de aço, a criação de um parque industrial? Por que escolher uma solução regional em vez de "big business" das siderúrgicas integradas? Como fazer para equacionar a solução para o mercado regional? Por que a siderurgia está sofrendo uma revolução tecnológica que não é só de como o aço é produzido, mas também de como fica toda a estrutura da indústria. Precisam-se examinar os parâmetros fundamentais da tecnologia de produção de aço, quer seja a necessidade de capital; a redução do consumo de energia; a preocupação com o meio ambiente na comunidade onde se situa; como também o modo de se aproximar das necessidades dos clientes. O Mato Grosso do Sul tem todas as condições para sediar um novo conceito de siderurgia integrada a upstream. Minério de ferro em abundância, gás natural como fonte de energia e como redutor do minério de ferro, diversos modais de transporte disponíveis, economia pujante e importação de todo o aço que consome.When analyzing a steel production opportunity, why should an industrial park be created? Why should a local enterprise be chosen instead of a large integrated mill? How to cope with the small local market? Because the steelmaking industry is facing a technological revolution, not only with the way steel is produced, but also with how the industry is structured, it is necessary to examine the fundamental parameters of the steelmaking technology: capital needs; lower energy consumption; environmental awareness; and ways to approach the customers and clients. The state of Mato Grosso do Sul has good prospects for hosting a modern integrated upstream steelmaking enterprise.. Iron ore is plentiful; natural gas as a source of energy and iron ore reductant is available from a nearby pipeline; transportation is readily available either via rail or road; agribusiness is assuring steady economic growth; and lastly, all the steel consumption in this area comes

  4. Multi-GNSS Opportunities and Challenges

    Science.gov (United States)

    Al-Shaery, A.; Zhang, S.; Lim, S.; Rizos, C.

    2012-04-01

    but also the hardware. Recent research has identified one of the challenges users may face if precise positioning is sought (Takac, 2009, Yamada et al., 2010, Wanninger, 2011). A user of heterogeneous receiver pairs will experience ambiguity fixing challenges due to inter-channel bias which cannot be cancelled by differencing GLONASS observations, pseudorange or carrier-phase. This paper outlines the opportunities and challenges of combining two currently fully operational GNSS systems (GPS and GLONASS) for precise positioning solutions. Discussion and analysis considering mathematical modelling challenges and users' selection of hardware constraints will be performed.

  5. Science Policy: A World of Opportunities

    Science.gov (United States)

    Mazza, Anne-Marie

    2017-01-01

    Opportunities are everywhere for scientists to engage in public policy, whether they stay at the bench or decide to move directly into the policy arena. In its 19th year, the National Academies of Sciences, Engineering, and Medicine's Christine Mirzayan Science and Technology Policy Graduate Fellowship Program provides early career individuals with the opportunity to spend 12 weeks at the Academies in Washington, DC learning about science and technology policy and the role that scientists and engineers play in advising the nation. Fellows leave the program prepared to engage in policy whether in DC, at the international level, or at the state and local level back at their home institutions. This discussion will explore these opportunities and highlight some of the positions pursued by Mirzayan alumni.

  6. Generating Innovation Opportunities - Exploring Unexpressed Customer Knowledge

    DEFF Research Database (Denmark)

    Kallio, Anne; Bergenholtz, Carsten

    2009-01-01

    generate innovation opportunities by exploring unexpressed customer knowledge? Based on an action research project in an organisation, the study presents an empirical example of how innovation opportunities can be generated by having salespeople apply an anthropological perspective when interacting......This study focuses on how a company can generate innovation opportunities by exploring unexpressed customer knowledge. In an open innovation paradigm, exploration can be performed via an in-depth or broad search of resources beyond organisational boundaries. Salespeople are an essential channel...... to an in-depth search in relation to customers, since salespeople possess rich knowledge of the customers. However, organisations do not pay adequate attention to the rich knowledge rising from the salespeople's experience and precognition. The paper answers the following question: How can a company...

  7. Factors Influencing the Identification of Sustainable Opportunities by SMEs: Empirical Evidence from Zambia

    Directory of Open Access Journals (Sweden)

    Progress Choongo

    2016-01-01

    Full Text Available This study uses the model of Patzelt and Shepherd (2011 to examine the factors influencing the identification of sustainable opportunities among SMEs in a developing country, Zambia. The factors under investigation include knowledge of the natural/social environment, perception of threats to the natural/social environment, altruism towards others and entrepreneurial knowledge. We interviewed 220 owner-managers in the trading and service sector who supply goods and services to the mining industry in Zambia. We found that altruism towards others was partially supported by our empirical results while the positive effects of knowledge of the natural/social environment and perception of threats to the natural/social environment on the identification of sustainable opportunities were not supported. Contrary to our expectations, entrepreneurial knowledge does not positively moderate the relationship between explanatory variables and the identification of sustainable opportunities. In sum, we found only limited empirical support for the model of Patzelt and Shepherd (2011 concerning the identification of sustainable opportunities. Our findings contribute to literature on entrepreneurship and sustainable opportunity identification by showing what factors influence the identification of sustainable opportunities. This can help us to create awareness among entrepreneurs regarding the effects of entrepreneurial activities on the environment and society; consequently, stimulating entrepreneurs to identify sustainable opportunities.

  8. Opportunity identification competence : explaining individual and exploring team opportunity identification by employees

    NARCIS (Netherlands)

    Baggen, Yvette

    2017-01-01

    Opportunities and their identification are of significant importance for competitiveness in today’s complex and turbulent business environment because they serve as a key influencing factor for new value-creation. Opportunity identification (OI) is interesting not only from the perspective of

  9. Basin-Scale Opportunity Assessment Initiative Background Literature Review

    Energy Technology Data Exchange (ETDEWEB)

    Saulsbury, Bo [ORNL; Geerlofs, Simon H. [Pacific Northwest National Laboratory (PNNL); Cada, Glenn F [ORNL; Bevelhimer, Mark S [ORNL

    2010-10-01

    As called for in the March 24, 2010, Memorandum of Understanding (MOU) for Hydropower, the U.S. Department of Energy (DOE), the U.S. Department of the Interior (DOI), the U.S. Army Corps of Engineers (USACE), environmental stakeholders, and the hydropower industry are collaborating to identify opportunities to simultaneously increase electricity generation and improve environmental services in river basins of the United States. New analytical tools provide an improved ability to understand, model, and visualize environmental and hydropower systems. Efficiencies and opportunities that might not be apparent in site-by-site analyses can be revealed through assessments at the river-basin scale. Information from basin-scale assessments could lead to better coordination of existing hydropower projects, or to inform siting decisions (e.g., balancing the removal of some dams with the construction of others), in order to meet renewable energy production and environmental goals. Basin-scale opportunity assessments would inform energy and environmental planning and address the cumulative effects of hydropower development and operations on river basin environmental quality in a way that quantifies energy-environment tradeoffs. Opportunity assessments would create information products, develop scenarios, and identify specific actions that agencies, developers, and stakeholders can take to locate new sustainable hydropower projects, increase the efficiency and environmental performance of existing projects, and restore and protect environmental quality in our nation's river basins. Government agencies and non-governmental organizations (NGO) have done significant work to understand and assess opportunities for both hydropower and environmental protection at the basin scale. Some initiatives have been successful, others less so, and there is a need to better understand the legacy of work on which this current project can build. This background literature review is intended

  10. Future Propulsion Opportunities for Commuter Airplanes

    Science.gov (United States)

    Strack, W. C.

    1982-01-01

    Commuter airplane propulsion opportunities are summarized. Consideration is given to advanced technology conventional turboprop engines, advanced propellers, and several unconventional alternatives: regenerative turboprops, rotaries, and diesels. Advanced versions of conventional turboprops (including propellers) offer 15-20 percent savings in fuel and 10-15 percent in DOC compared to the new crop of 1500-2000 SHP engines currently in development. Unconventional engines could boost the fuel savings to 30-40 percent. The conclusion is that several important opportunities exist and, therefore, powerplant technology need not plateau.

  11. Nanotechnology in biorobotics: opportunities and challenges

    Science.gov (United States)

    Ricotti, Leonardo; Menciassi, Arianna

    2015-02-01

    Nanotechnology recently opened a series of unexpected technological opportunities that drove the emergence of novel scientific and technological fields, which have the potential to dramatically change the lives of millions of citizens. Some of these opportunities have been already caught by researchers working in the different fields related to biorobotics, while other exciting possibilities still lie on the horizon. This article highlights how nanotechnology applications recently impacted the development of advanced solutions for actuation and sensing and the achievement of microrobots, nanorobots, and non-conventional larger robotic systems. The open challenges are described, together with the most promising research avenues involving nanotechnology.

  12. Identifying PHM market and network opportunities.

    Science.gov (United States)

    Grube, Mark E; Krishnaswamy, Anand; Poziemski, John; York, Robert W

    2015-11-01

    Two key processes for healthcare organizations seeking to assume a financially sustainable role in population health management (PHM), after laying the groundwork for the effort, are to identify potential PHM market opportunities and determine the scope of the PHM network. Key variables organizations should consider with respect to market opportunities include the patient population, the overall insurance/employer market, and available types of insurance products. Regarding the network's scope, organizations should consider both traditional strategic criteria for a viable network and at least five additional criteria: network essentiality and PHM care continuum, network adequacy, service distribution right-sizing, network growth strategy, and organizational agility.

  13. Research opportunities to advance solar energy utilization.

    Science.gov (United States)

    Lewis, Nathan S

    2016-01-22

    Major developments, as well as remaining challenges and the associated research opportunities, are evaluated for three technologically distinct approaches to solar energy utilization: solar electricity, solar thermal, and solar fuels technologies. Much progress has been made, but research opportunities are still present for all approaches. Both evolutionary and revolutionary technology development, involving foundational research, applied research, learning by doing, demonstration projects, and deployment at scale will be needed to continue this technology-innovation ecosystem. Most of the approaches still offer the potential to provide much higher efficiencies, much lower costs, improved scalability, and new functionality, relative to the embodiments of solar energy-conversion systems that have been developed to date.

  14. Research Funding Opportunities for Early Career Scientists

    Science.gov (United States)

    Wiener, Richard

    2009-10-01

    This talk will describe opportunities for early career faculty members in the physical sciences to obtain funding for scientific research and educational projects. I will discuss programs offered by Research Corporation for Science Advancement, a private nonprofit foundation, which include opportunities for scientists at primarily undergraduate institutions and at research universities. I will emphasize strategies for successful grant writing. The target audience is early career academic scientists in Astronomy, Physics, and related fields, as well as graduate students and postdoctoral researchers considering careers in these academic disciplines.

  15. Nanotechnology in biorobotics: opportunities and challenges

    Energy Technology Data Exchange (ETDEWEB)

    Ricotti, Leonardo, E-mail: l.ricotti@sssup.it; Menciassi, Arianna [Scuola Superiore Sant’Anna, The BioRobotics Institute (Italy)

    2015-02-15

    Nanotechnology recently opened a series of unexpected technological opportunities that drove the emergence of novel scientific and technological fields, which have the potential to dramatically change the lives of millions of citizens. Some of these opportunities have been already caught by researchers working in the different fields related to biorobotics, while other exciting possibilities still lie on the horizon. This article highlights how nanotechnology applications recently impacted the development of advanced solutions for actuation and sensing and the achievement of microrobots, nanorobots, and non-conventional larger robotic systems. The open challenges are described, together with the most promising research avenues involving nanotechnology.

  16. Architects of postmodern information society and opportunities of its users

    Directory of Open Access Journals (Sweden)

    Senka Hočevar Ciuha

    2010-12-01

    The strengths of the presented mental models rest in their potential to provide sufficient complexity and challenge to engage participants in lively, thought-provoking exercises, with which they can search for legitimate answers to real-world problems. Mental models provide opportunities for students to practice and become familiar with tools and resources, engage them with a variety of problem-solving strategies, and create the next best thing to workplace experience. Teaching with mental models for a positive learning experience may require usually unfamiliar and difficult facilitation skills and flexibility to walk students through unfamiliar processes with a great number of possibilities and vagaries. An evolving perspective of mental models is based on new paradigms of the theory of lifelong education.

  17. Missed Opportunities for Hepatitis A Vaccination, National Immunization Survey-Child, 2013.

    Science.gov (United States)

    Casillas, Shannon M; Bednarczyk, Robert A

    2017-08-01

    To quantify the number of missed opportunities for vaccination with hepatitis A vaccine in children and assess the association of missed opportunities for hepatitis A vaccination with covariates of interest. Weighted data from the 2013 National Immunization Survey of US children aged 19-35 months were used. Analysis was restricted to children with provider-verified vaccination history (n = 13 460). Missed opportunities for vaccination were quantified by determining the number of medical visits a child made when another vaccine was administered during eligibility for hepatitis A vaccine, but hepatitis A vaccine was not administered. Cross-sectional bivariate and multivariate polytomous logistic regression were used to assess the association of missed opportunities for vaccination with child and maternal demographic, socioeconomic, and geographic covariates. In 2013, 85% of children in our study population had initiated the hepatitis A vaccine series, and 60% received 2 or more doses. Children who received zero doses of hepatitis A vaccine had an average of 1.77 missed opportunities for vaccination compared with 0.43 missed opportunities for vaccination in those receiving 2 doses. Children with 2 or more missed opportunities for vaccination initiated the vaccine series 6 months later than children without missed opportunities. In the fully adjusted multivariate model, children who were younger, had ever received WIC benefits, or lived in a state with childcare entry mandates were at a reduced odds for 2 or more missed opportunities for vaccination; children living in the Northeast census region were at an increased odds. Missed opportunities for vaccination likely contribute to the poor coverage for hepatitis A vaccination in children; it is important to understand why children are not receiving the vaccine when eligible. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. Unveiling information on opportunity costs in REDD

    DEFF Research Database (Denmark)

    Delacote, Philip; Palmer, Charles; Bakkegaard, Riyong Kim;

    2014-01-01

    Improving information about individual opportunity costs of deforestation agents has the potential to increase the efficiency of REDD when it takes the form of a payment for environmental services scheme. However, objectives pursued in REDD projects may vary across policy makers. Within a theoret...

  19. Farm seed opportunities : conservation, breeding and production

    NARCIS (Netherlands)

    Kik, C.; Louwaars, N.P.; Burg, van der W.J.; Almekinders, C.J.M.

    2011-01-01

    Farm Seed Opportunities (FSO), a research project in the FP6 European Research Framework (2007-2009), was targeted to support the implementation of seed regulations on conservation varieties (directive 98/95/EC and new directives 2008/62/EC and 2009/145/CE) and to propose complementary seed

  20. Biofuels and Fisheries: Risks and Opportunities .

    Science.gov (United States)

    A rapidly developing biofuels industry in the U.S. and around the globe poses novel environmental challenges and opportunities, with implications for teh health and sustainability of fisheries. Changes in land uses and agricultural practices for production of biofuel feedstocks ...

  1. Views on personal networks and business opportunities

    DEFF Research Database (Denmark)

    Windekilde, Iwona Maria; Roswall, Rune

    2009-01-01

    The EU project MAGNET-Beyond has examined the business opportunities regarding Personal Networks (PN) for the typical value network stakeholders. In the current communication markets, companies deliver services to customers in cooperation with other market players profiting on different business...

  2. Employment Opportunities in Agribusiness. A Report.

    Science.gov (United States)

    Dempsey, Richard E.

    This report, which was written during a project to develop a better understanding of which occupations may relate to agribusiness and to identify employment opportunities in agribusiness, is designed to assist state occupational information coordinating committees and state employment security agencies in developing special reports/lists of…

  3. Opportunity to Learn: The Health Connection.

    Science.gov (United States)

    Jackson, Shirley A.

    1993-01-01

    Reviews the following health issues related to the opportunity to learn for poor African-American and other minority children: (1) inadequate prenatal care; (2) malnutrition; (3) childhood diseases and illnesses; (4) unsafe environments and violence; (5) teenage sexual activity, pregnancy, and AIDS; (6) substance use and abuse; and (7) mental and…

  4. Learning Motivation: The Role of Opportunity

    Science.gov (United States)

    McCaslin, Mary

    2008-01-01

    Background/Context: Student motivation typically has been studied as it relates to extrinsic (e.g., reinforcement) and intrinsic (e.g., choice) sources of influence. Our observation of Grades 3-5 classrooms engaged in Comprehensive School Reform (CSR), however, unexpectedly indicated that opportunities for both rewards and choice were scarce. This…

  5. Learning paths and OER: trends and opportunities

    NARCIS (Netherlands)

    Janssen, José; Berlanga, Adriana; Koper, Rob

    2013-01-01

    Janssen, J., Berlanga, A. J., & Koper, R. (2013). Learning paths and OER: trends and opportunities. In R. Jacobi, H. Jelgerhuis, & N. van der Woert (Eds.), Trendreport Open Educational Resources 2013 (pp. 76-80). Utrecht: SURF Foundation - Special Interest Group Open Educational Resources SURF. Fina

  6. Challenges and Opportunities in Teaching Mathematics

    Science.gov (United States)

    Goos, Merrilyn

    2016-01-01

    At the special conference celebrating the 50th anniversary of the Australian Association of Mathematics Teachers (AAMT), the author was asked to speak about the challenges and opportunities in teaching mathematics as a stimulus for discussion of AAMT's "future directions". With an open invitation to be a little provocative, the author…

  7. Hotels Gear up for Olympic Opportunities

    Institute of Scientific and Technical Information of China (English)

    WANGPEI

    2005-01-01

    The 2008 Olympic games is a great opportunity for China to present itself on the world stage. As the host city, Beijing is preparing to extend the best hospitality it can to the many expected guests from all around the world.

  8. Information exposure, opportunity evaluation and entrepreneurial action

    DEFF Research Database (Denmark)

    Autio, E.; Dahlander, L.; Frederiksen, Lars

    2013-01-01

    We study how an individual's exposure to external information regulates the evaluation of entrepreneurial opportunities and entrepreneurial action. Combining data from interviews, a survey, and a comprehensive web log of an online user community spanning eight years, we find that technical inform...

  9. Environmental Management in Bolivia : Innovations and Opportunities

    OpenAIRE

    2013-01-01

    Pollution management is at the top of the development agenda of Bolivia, and this program helps address it in a cross-sectoral manner. In the context of the implementation of the program environmental management in Bolivia: innovations and opportunities which was conducted from September 2010 until October 2012, the World Bank has implemented a technical assistance program and supported a ...

  10. Teaching science students to identify entrepreneurial opportunities

    NARCIS (Netherlands)

    Nab, J.

    2015-01-01

    This dissertation describes a research project on teaching science students to identify entrepreneurial opportunities, which is a core competence for entrepreneurs that should be emphasized in education. This research consists of four studies. The first case study aims at finding design strategies f

  11. The Window of locational opportunity-concept

    NARCIS (Netherlands)

    Boschma, Ron

    1996-01-01

    This article aims to set out a theoretical concept, i.e. the Window of Locational Opportunity concept, which accounts for notions like indeterminacy, human agency and historical accidents when explaining the spatial pattern of newly emerging industries. We will state that their spatial formation doe

  12. Teaching science students to identify entrepreneurial opportunities

    NARCIS (Netherlands)

    Nab, J.|info:eu-repo/dai/nl/304827614

    2015-01-01

    This dissertation describes a research project on teaching science students to identify entrepreneurial opportunities, which is a core competence for entrepreneurs that should be emphasized in education. This research consists of four studies. The first case study aims at finding design strategies

  13. Community Languages in Europe : Challenges and Opportunities

    NARCIS (Netherlands)

    McPake, J.; Martyniuk, W.; Aarts, R.; Broeder, Peter; Latomaa, Sirkku; Mijares, Laura; Tinsley, Teresa

    2004-01-01

    This paper reviews issues affecting school students’ learning of community languages across Europe, with the aim of identifying both challenges and opportunities inherent in the current context. Language education pol icy has become more inclusive of late, addressing the full range of languages rath

  14. Farmers’ perception of opportunities for farm development

    NARCIS (Netherlands)

    Methorst, Ron

    2016-01-01

    Differences in the perception of opportunities for farm development is researched in this thesis in relation to differences in the embedding of the farm in the socio-material context. This study contributes to a Sociology of Entrepreneurship in focusing on the decision-maker specific aspects using t

  15. Opportunities for pharmaceutical care with critical pathways.

    Science.gov (United States)

    Koch, K E

    1995-01-01

    Critical pathways are multidisciplinary tools designed to improve patient care and efficiency. Almost every path requires some type of pharmacotherapeutic intervention, from selection of surgical prophylaxis to management of anticoagulation. Pharmacists should become involved with the critical pathway process because it offers an excellent opportunity to incorporate pharmaceutical care and to meet Joint Commission on Accreditation of Healthcare Organization compliance criteria.

  16. General Education Reform: Opportunities for Institutional Alignment

    Science.gov (United States)

    Fuess, Scott M., Jr.; Mitchell, Nancy D.

    2011-01-01

    General education reform provides strategic opportunities for departments. This article analyzes reform at the University of Nebraska-Lincoln, illustrating how departments could use the reform process to clarify their strategic planning, align with institutional goals, and steer the university closer to departmental objectives. (Contains 1 table.)

  17. Strategic Opportunities for Cooperative Extension. Executive Summary

    Science.gov (United States)

    National Association of State Universities and Land-Grant Colleges, 2007

    2007-01-01

    In this new century, opportunities exist to help advance America's greatness in the midst of many challenges. Energy, water, food, environment, health, economic productivity, global competitiveness, and the quality of the living environments are all paramount to the future. Extension is, as a part of higher education, prepared to create new…

  18. Nurse executives: new roles, new opportunities.

    Science.gov (United States)

    Kleinman, C S

    1999-01-01

    As women have been nursing since the earliest days of recorded civilization, so nurses have been associated with health care since the earliest days of recorded medical history. Gender and function have been inextricably woven in ways that created a struggle for success within a male-dominated industry. Nurses, as women, have been undervalued as, until recently, their role in health care has been similarly undervalued. Changing realities in the health care environment have created an opportunity for women's unique skills and talents to be revalued in a way that offers new opportunities for nurses. Teamwork, global thinking, multitasking, creativity, and flexibility are characteristics that have assumed new importance in the marketplace. Nursing leaders possess these attributes, along with a strong clinical foundation that is integrated with knowledge of sound business principles. This combination now positions nurse executives to reach the highest levels of heath care administration. Critical to this achievement is the professional credibility obtained through education at the master's degree level in health care and nursing administration programs that provide the essential tools for professional success. New opportunities for nurse executives afford educators in health care and nursing administration similar opportunities to develop and market programs to this large group of health care professionals who are seeking graduate education in increasing numbers.

  19. Challenges and Opportunities in Teaching Mathematics

    Science.gov (United States)

    Goos, Merrilyn

    2016-01-01

    At the special conference celebrating the 50th anniversary of the Australian Association of Mathematics Teachers (AAMT), the author was asked to speak about the challenges and opportunities in teaching mathematics as a stimulus for discussion of AAMT's "future directions". With an open invitation to be a little provocative, the author…

  20. Teaching science students to identify entrepreneurial opportunities

    NARCIS (Netherlands)

    Nab, J.

    2015-01-01

    This dissertation describes a research project on teaching science students to identify entrepreneurial opportunities, which is a core competence for entrepreneurs that should be emphasized in education. This research consists of four studies. The first case study aims at finding design strategies f

  1. Identifying opportunities in online-communities

    DEFF Research Database (Denmark)

    Hienerth, C.; Lettl, Christopher

    how this phenomenon - as manifested in user communities - can be used to derive deeper insights into the prominent phases of opportunity identification, evaluation and exploitation. We also outline how user communities create new avenues for empirical research on these early entrepreneurial processes...

  2. Opportunity Theory and Agricultural Crime Victimization

    Science.gov (United States)

    Mears, Daniel P.; Scott, Michelle L.; Bhati, Avinash S.

    2007-01-01

    A growing body of research lends support to opportunity theory and its variants, but has yet to focus systematically on a number of specific offenses and contexts. Typically, the more crimes and contexts to which a theory applies, the broader its scope and range, respectively, and thus generalizability. In this paper, we focus on agricultural…

  3. Advancing Sustainable Surface Engineering: Challenges & Future Opportunities

    Science.gov (United States)

    2014-11-01

    Energy costs – Inefficient processes – Supply chain risk • Reduced Liability – Environmental and occupational • Increased Availability...2013 Noblis, Inc. Advancing Sustainable Surface Engineering: Challenges & Future Opportunities Dr. Jeffrey Marqusee Chief Scientist...control number. 1. REPORT DATE NOV 2014 2. REPORT TYPE 3. DATES COVERED 00-00-2014 to 00-00-2014 4. TITLE AND SUBTITLE Advancing Sustainable

  4. Transhumanism: projections of opportunities, risks and dangers

    OpenAIRE

    Kindras, Natasha

    2013-01-01

    The experience of recent decades reveals a special changeability of various aspects of human existence. The nomadic movement in space «trans» is especially typical. Modern philosophical thought for these processes uses the term «transhumanism». The paper considers scientifically oriented outlook of transhumanism, analyzes the opportunities, risks and dangers of biotechnological transformation of human into posthuman.

  5. Looking Forward: New Challenges and Opportunities

    Science.gov (United States)

    Bushnell, Elizabeth J.

    2012-01-01

    It is essential for higher education professionals to remain abreast of industry trends, emerging fields, and changing requirements that affect the job market and advanced education opportunities for new graduates. Equally important is a continual review of evolving strategies for success in the job search itself. Common practices in today's…

  6. Undergraduate Research Mentoring: Obstacles and Opportunities

    Science.gov (United States)

    Johnson, W. Brad; Behling, Laura L.; Miller, Paul; Vandermaas-Peeler, Maureen

    2015-01-01

    Researchers and policy-makers in higher education increasingly espouse the view that undergraduate students should have the opportunity to learn about scholarship and research in the context of faculty-mentored research experiences. There is mounting consensus that mentored undergraduate research should be standard pedagogical practice in all…

  7. Pitfalls and opportunities for environmental marketers.

    Science.gov (United States)

    Gillespie, R J

    1992-01-01

    Issues such as global warming, ozone depletion, insufficient landfill capacity, and excess packaging are foremost on the minds of consumers. Companies face a myriad of environmental challenges, but they also recognize the opportunities to be gained by implementing responsible marketing action plans.

  8. Northeast Pharmaceutical from Relocation Acquires Opportunity

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ Northeast Pharmaceutical Group Co., Ltd., an old state-owned company, has met a major development opportunity in its relocation. According to the municipal program made by Shenyang City, Northeast Pharmaceutical Group located in the Tiexi District of Shenyang will move to Shenyang Xihe Development Zone.

  9. Threats and opportunities for information systems outsourcing

    CSIR Research Space (South Africa)

    Smuts, H

    2015-10-01

    Full Text Available to outsource, as well as the success of an IS outsourcing arrangement. Managing successful IS outsourcing relationships is concerned with exploiting outsourcing opportunities and avoiding outsourcing threats. The aim of this paper is to share the findings of a...

  10. ASBO Eagle Institute: A Leadership Opportunity

    Science.gov (United States)

    Scharff, James

    2012-01-01

    Each summer, ASBO International conducts an Eagle Institute leadership session in the Washington, D.C., area that provides a group of about 25 participants, including Eagle Award recipients, an opportunity to network with and learn from exemplary leaders inside and outside the field of school business management. Each year, the focus of the…

  11. Materials Education: Opportunities over a Lifetime

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Iver E.; Schwartz, Lyle H.; Faber, Katherine T.; Cargill III, G. Slade; Houston, Betsy

    2003-10-28

    A report, in the form of abbreviated notes, of the 17th Biennial Conference on National Materials Policy ''Materials Education: Opportunities over a Lifetime'' held May 20-21, 2002 in College Park, MD, sponsored by the Federation of Materials Societies and the University Materials Council.

  12. The Crisis and Opportunities in Library Leadership.

    Science.gov (United States)

    Riggs, Donald E.

    2001-01-01

    Discusses the need for strong leadership in libraries. Topics include the distinction between management and leadership; myths about leadership; leading change; expected qualities of effective leaders, including creativity, innovation and entrepreneurship, planning, and communicating; and librarian's opportunities for leadership development. (LRW)

  13. Nanosized metal clusters : Challenges and opportunities

    NARCIS (Netherlands)

    De Hosson, JTM; Palasantzas, G; Vystavel, T; Koch, S

    2004-01-01

    This article presents challenges and opportunities to control the microstructure in nanostructured coatings using a nanocluster source. The cluster size distribution is monodisperse and the kinetic energy of the clusters during deposition can be varied. Interestingly, the clusters are grown in extre

  14. Using strategic foresight to assess conservation opportunity.

    Science.gov (United States)

    Cook, Carly N; Wintle, Bonnie C; Aldrich, Stephen C; Wintle, Brendan A

    2014-12-01

    The nature of conservation challenges can foster a reactive, rather than proactive approach to decision making. Failure to anticipate problems before they escalate results in the need for more costly and time-consuming solutions. Proactive conservation requires forward-looking approaches to decision making that consider possible futures without being overly constrained by the past. Strategic foresight provides a structured process for considering the most desirable future and for mapping the most efficient and effective approaches to promoting that future with tools that facilitate creative thinking. The process involves 6 steps: setting the scope, collecting inputs, analyzing signals, interpreting the information, determining how to act, and implementing the outcomes. Strategic foresight is ideal for seeking, recognizing, and realizing conservation opportunities because it explicitly encourages a broad-minded, forward-looking perspective on an issue. Despite its potential value, the foresight process is rarely used to address conservation issues, and previous attempts have generally failed to influence policy. We present the strategic foresight process as it can be used for proactive conservation planning, describing some of the key tools in the foresight tool kit and how they can be used to identify and exploit different types of conservation opportunities. Scanning is an important tool for collecting and organizing diverse streams of information and can be used to recognize new opportunities and those that could be created. Scenario planning explores how current trends, drivers of change, and key uncertainties might influence the future and can be used to identify barriers to opportunities. Backcasting is used to map out a path to a goal and can determine how to remove barriers to opportunities. We highlight how the foresight process was used to identify conservation opportunities during the development of a strategic plan to address climate change in New York

  15. 24 CFR 135.40 - Providing other economic opportunities.

    Science.gov (United States)

    2010-04-01

    ... EMPLOYMENT AND BUSINESS OPPORTUNITY ECONOMIC OPPORTUNITIES FOR LOW- AND VERY LOW-INCOME PERSONS Economic... economic opportunities offer an effective means of empowering low-income persons, a recipient is encouraged to undertake efforts to provide to low-income persons economic opportunities other than...

  16. Internet platforms for lifelong learning: a continuum of opportunity.

    Science.gov (United States)

    Sedory Holzer, Susan E; Kokemueller, Phillip

    2007-12-01

    Access to knowledge through the Internet has spawned a world of online learning, stimulating a new passion for lifelong learning in academia, professional environments, the workplace, and at home. This article takes a fresh look at the wide spectrum of opportunities for online medical education for physicians. We first explore a continuum of "e-learning" models and then look at the range of platforms used to support these systems. We will also look forward to the options likely to change e-learning in the near future and improve physician performance and patient outcomes.

  17. Methane recovery from animal manures: A current opportunities casebook

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-08-01

    This Casebook examines some of the current opportunities for the recovery of methane from the anaerobic digestion of animal manures US livestock operations currently employ four types of anaerobic digester technology: Slurry, plug flow, complete mix, and covered lagoon. An introduction to the engineering economies of these technologies is provided, and possible end-use applications for the methane gas generated by the digestion process are discussed. The economic evaluations are based on engineering studies of digesters that generate electricity from the recovered methane. Regression models, which can be used to estimate digester cost and internal rate of return, are developed from the evaluations.

  18. New drug discovery: extraordinary opportunities in an uncertain time.

    Science.gov (United States)

    Kinch, Michael S; Flath, Richard

    2015-11-01

    The way in which new medicines are discovered has irreversibly changed and the future sustainability of the enterprise is characterized by an unprecedented period of uncertainty. Herein, we convey that these changes provide unprecedented opportunities for many different players within the private and public sectors to work together and develop new models that ensure the sustainability of activities that have had an extraordinary impact; in terms of promoting public health and driving economic value. Specific examples of experiments are provided to demonstrate some of the new thinking that will be needed to ensure continuation of new drug discovery.

  19. Opportunity costs associated with caring for older Mexican-Americans

    OpenAIRE

    Brown, H. Shelton; Herrera, Angelica P.; Angel, Jacqueline L.

    2013-01-01

    Long-term care use among older Mexican-Americans is poorly understood, despite the adverse effects on health and economic disadvantage in this vulnerable population. This study examines gender-based risk of long-term care use in 628 women and 391 men, age 70 and over in the 2000-01 and 2004-05 waves of the Hispanic Established Populations for Epidemiologic Studies of the Elderly. Logistic regression models are employed to assess the impact of the opportunity cost implications of family suppor...

  20. Accountable care organizations for neuroradiologists: threats and opportunities.

    Science.gov (United States)

    Lexa, Frank J; Berlin, Jonathan W

    2012-08-01

    Accountable care organizations (ACOs) are one of the more interesting and (perhaps) highest impact components of the 2010 Federal health care bill. Neuroradiologists should examine them carefully for opportunities to participate and contribute to ACOs as well as to understand the potential threats. Although there are questions about the viability of the proposed models, neuroradiologists should not assume this is a fad. All specialists should pay close attention to the evolution of ACOs. It seems likely that many of their features will come to pass during the coming decades with substantial impact on the profession. Copyright © 2012 Elsevier Inc. All rights reserved.

  1. Improvement of Salinity Stress Tolerance in Rice: Challenges and Opportunities

    Directory of Open Access Journals (Sweden)

    Thi My Linh Hoang

    2016-10-01

    Full Text Available Rice (Oryza sativa L. is an important staple crop that feeds more than one half of the world’s population and is the model system for monocotyledonous plants. However, rice is very sensitive to salinity and is the most salt sensitive cereal crop with a threshold of 3 dSm−1 for most cultivated varieties. Despite many attempts using different strategies to improve salinity tolerance in rice, the achievements so far are quite modest. This review aims to discuss challenges that hinder the improvement of salinity stress tolerance in rice as well as potential opportunities for enhancing salinity stress tolerance in this important crop.

  2. Spectrum Opportunity Detection: How Good Is Listen-before-Talk?

    Science.gov (United States)

    2007-11-01

    a general signal propagation and interference model. Theorem 1: For a pair of secondary users A (transmitter) and B (receiver), let Prx (A) denote the...reception at B. Let Ptx(A) denote the set of all primary users who have potential receivers in Prx (A). Detecting primary signals is equivalent to detecting...spectrum opportunities if and only if for any primary user X ∈ Ptx(A)∩Ptx(B), all potential receivers of X are in Prx (A). By Definitions 1 and 2

  3. VIRTUALITY THE OPPORTUNITY TO INNOVATE IN EDUCATION: A MODEL FOR THE DESIGN OF VIRTUAL LEARNING ENVIRONMENTS / LA VIRTUALIDAD UNA OPORTUNIDAD PARA INNOVAR EN EDUCACIÓN: UN MODELO PARA EL DISEÑO DE ENTORNOS VIRTUALES DE APRENDIZAJE

    Directory of Open Access Journals (Sweden)

    Juan Eusebio Silva Quiroz

    2014-01-01

    Full Text Available The use of information technology and media, especially the most popular Learning Management Systems such as LMS or learning management systems, make it possible to expand the teaching in undergraduate and graduate students at universities, along with staff training in enterprises, beyond the boundaries of the classroom. The LMS have enhanced the design of virtual learning environments, supporting, complementing, or substituting for face class completely online training. Low socio-constructivist pedagogical models, these training scenarios teaching approach to training informal spaces allowing innovation in teaching. Thus, this article seeks to answer questions like What are virtual learning environments (EVA? How to enrich and innovate the educational experience incorporating EVA? What elements should be considered a model for designing an EVA? How to implement this model on a platform like MOODLE? RESUMEN El uso de las tecnologías de la información y comunicación, especialmente los Learning Management Systems más conocidos como LMS o sistemas para gestión del aprendizaje, posibilitan ampliar la docencia en pre y post grado en las universidades, junto con la formación del personal en las empresas, más allá de las fronteras del aula. Lo LMS, han potenciado el diseño de entornos virtuales de aprendizajes, apoyando, complementando, o sustituyendo la clase presencial por formación completamente online. Bajo modelos pedagógicos socio-constructivistas, estos escenarios formativos acercan la docencia, a los espacios informales de formación permitiendo innovar en la docencia. De este modo, este artículo busca responder interrogantes que ¿Qué son los entornos virtuales de aprendizaje (EVA?, ¿cómo enriquecer e innovar en la experiencia formativa incorporando EVA?, ¿qué elementos debería considerar un modelo para diseñar un EVA?, ¿cómo implementar ese modelo en una plataforma como MOODLE?

  4. On Equal Opportunities at CERN: A report prepared for the Equal Opportunities Advisory Panel

    CERN Document Server

    Rimmer, E M

    2001-01-01

    This report has been prepared at the request of the Equal Opportunities Advisory Panel. It is an attempt to demonstrate, simply and clearly, some additional facts relating to gender differences shown in previous reports of the Panel.

  5. Global climate change and contaminants--an overview of opportunities and priorities for modelling the potential implications for long-term human exposure to organic compounds in the Arctic.

    Science.gov (United States)

    Armitage, James M; Quinn, Cristina L; Wania, Frank

    2011-06-01

    This overview seeks to provide context and insight into the relative importance of different aspects related to global climate change for the exposure of Northern residents to organic contaminants. A key objective is to identify, from the perspective of researchers engaged in contaminant fate, transport and bioaccumulation modelling, the most useful research questions with respect to projecting the long-term trends in human exposure. Monitoring studies, modelling results, the magnitude of projected changes and simplified quantitative approaches are used to inform the discussion. Besides the influence of temperature on contaminant amplification and distribution, accumulation of organic contaminants in the Arctic is expected to be particularly sensitive to the reduction/elimination of sea-ice cover and also changes to the frequency and intensity of precipitation events (most notably for substances that are highly susceptible to precipitation scavenging). Changes to key food-web interactions, in particular the introduction of additional trophic levels, have the potential to exert a relatively high influence on contaminant exposure but the likelihood of such changes is difficult to assess. Similarly, changes in primary productivity and dynamics of organic matter in aquatic systems could be influential for very hydrophobic contaminants, but the magnitude of change that may occur is uncertain. Shifts in the amount and location of chemical use and emissions are key considerations, in particular if substances with relatively low long range transport potential are used in closer proximity to, or even within, the Arctic in the future. Temperature-dependent increases in emissions via (re)volatilization from primary and secondary sources outside the Arctic are also important in this regard. An increased frequency of boreal forest fires has relevance for compounds emitted via biomass burning and revolatilization from soil during/after burns but compound-specific analyses are

  6. Opportunity View of 'Lyell' Layer (False Color)

    Science.gov (United States)

    2008-01-01

    This view from NASA's Mars Exploration Rover Opportunity shows bedrock within a stratigraphic layer informally named 'Lyell,' which is the lowermost of three layers the rover has examined at a bright band around the inside of Victoria Crater. Opportunity used its panoramic camera (Pancam) to capture this image with low-sun angle at a local solar time of 3:21 p.m. during the rover's 1,433rd Martian day, of sol (Feb. 4, 2008). This view combines separate images taken through the Pancam filters centered on wavelengths of 753 nanometers, 535 nanometers and 432 nanometers. It is presented in a false-color stretch to bring out subtle color differences in the scene.

  7. Challenges and opportunities of international clinical practica.

    Science.gov (United States)

    Mill, Judy E; Yonge, Olive J; Cameron, Brenda L

    2005-01-01

    International clinical practica are a strategy to integrate a global dimension in nursing curricula and achieve culturally sensitive nursing practice. In this paper, a review of the history and development of international practica for nursing students is presented, and research evaluating the effectiveness and impact of international experiences is analyzed. A description of experiences working with Canadian nursing students is used to highlight the challenges and opportunities inherent to international clinical practica. International student experiences involving clinical practica pose challenges that are additional to, and often more complex than, those faced in traditional international, course-based exchanges. The significant opportunities, however, continue to make international student practica a desirable and positive experience for Canadian nursing students.

  8. Two Years Onboard the MER Opportunity Rover

    Science.gov (United States)

    Estlin, Tara; Anderson, Robert C.; Bornstein, Benjamin; Burl, Michael; Castano, Rebecca; Gaines, Daniel; Judd, Michele; Thompson, David R.

    2012-01-01

    The Autonomous Exploration for Gathering Increased Science (AEGIS) system provides automated data collection for planetary rovers. AEGIS is currently being used onboard the Mars Exploration Rover (MER) mission's Opportunity to provide autonomous targeting of the MER Panoramic camera. Prior to AEGIS, targeted data was collected in a manual fashion where targets were manually identified in images transmitted to Earth and the rover had to remain in the same location for one to several communication cycles. AEGIS enables targeted data to be rapidly acquired with no delays for ground communication. Targets are selected by AEGIS through the use of onboard data analysis techniques that are guided by scientist-specified objectives. This paper provides an overview of the how AEGIS has been used on the Opportunity rover, focusing on usage that occurred during a 21 kilometer historic trek to the Mars Endeavour crater.

  9. Honduras geothermal development: Regulations and opportunities

    Energy Technology Data Exchange (ETDEWEB)

    Goff, S.J.; Winchester, W.W.

    1994-09-01

    The US Department of Energy (DOE) through the Assistant Secretary for Policy, Planning, and Evaluation funded a project to review and evaluate existing power sector laws and regulations in Honduras. Also included in the scope of the project was a review of regulations pertaining to the privatization of state-run companies. We paid particular attention to regulations which might influence opportunities to develop and commercialize Honduras` geothermal resources. We believe that Honduras is well on the road to attracting foreign investment and has planned or has already in place much of the infrastructure and legal guarantees which encourage the influx of private funds from abroad. In addition, in light of current power rationing and Honduras` new and increasing awareness of the negative effects of power sector development on the environment, geothermal energy development is even more attractive. Combined, these factors create a variety of opportunities. The potential for private sector development of geothermal positive.

  10. Opportunity's Surroundings After Sol 1820 Drive

    Science.gov (United States)

    2009-01-01

    NASA's Mars Exploration Rover Opportunity used its navigation camera to take the images combined into this full-circle view of the rover's surroundings during the 1,820th to 1,822nd Martian days, or sols, of Opportunity's surface mission (March 7 to 9, 2009). South is at the center; north at both ends. The rover had driven 20.6 meters toward the northwest on Sol 1820 before beginning to take the frames in this view. Tracks from that drive recede southwestward. For scale, the distance between the parallel wheel tracks is about 1 meter (about 40 inches). The terrain in this portion of Mars' Meridiani Planum region includes dark-toned sand ripples and small exposures of lighter-toned bedrock. This view is presented as a cylindrical projection with geometric seam correction.

  11. Opportunity's View on Sols 1803 and 1804

    Science.gov (United States)

    2009-01-01

    NASA's Mars Exploration Rover Opportunity used its navigation camera to take the images combined into this full-circle view of the rover's surroundings during the 1,803rd and 1,804th Martian days, or sols, of Opportunity's surface mission (Feb. 18 and 19, 2009). South is at the center; north at both ends. The rover had driven 55 meters on Sol 1803 before beginning to take the frames in this view. Tracks from that drive recede northward. For scale, the distance between the parallel wheel tracks is about 1 meter (about 40 inches). The terrain in this portion of Mars' Meridiani Planum region includes dark-toned sand ripples and lighter-toned bedrock. This view is presented as a cylindrical projection with geometric seam correction.

  12. Paradoxes and Opportunities in Logistic Outsourcing Research

    Directory of Open Access Journals (Sweden)

    Đurđica Stojanović

    2012-11-01

    Full Text Available Historically, very few logistic trends have caught the attention of academics and practitioners to the same extent as outsourcing. A comprehensive literature review reveals two reasons for this continual topicality. The problem complexity and the business environment dynamics – including an interaction with other main trends in logistics and modern supply chains – both led to a permanent literature gap, indicating the need to explore some new aspects of logistics outsourcing (LO. In this paper, a new LO research perspective has been explored by identifying some weaknesses in the main LO research streams and related common viewpoints which led to six ‘logistics outsourcing research paradoxes’. Each of these paradoxes is briefly described and their links with research streams and common views on LO discussed. Finally, the nature of some known opportunities for further research is better explained and some overlooked research opportunities are highlighted.

  13. Editorial: Global Opportunities and Local Businesses

    Directory of Open Access Journals (Sweden)

    Krzysztof Wach

    2013-03-01

    Full Text Available The theme of the first issue is very multi‐disciplinary. It links economics with management by exploring global opportunities through particular local businesses. The European Union, as all of Europe, is now facing grand global challenges that primarily relate to economic issues. As stipulated by H. Sirkin, J. Hemerling and A. Bhattacharya in their world‐famous book: Globality: Competing with Everyone from Everywhere for Everything, in the resent future the European, American and Japanese firms will compete not only with each, other but increasingly with very competitive Chinese, Indian, South American, and even African firms, which currently may seem farfetched (Kotler & Caslione, 2009, p. 29. We believe it is extremely important to recognise global opportunities, which have resulted from globalisation, internationalisation and Europeanisation processes (Wach, 2012, pp. 137‐150 and 298‐299.

  14. Regulatory environment and claims - limits and opportunities.

    Science.gov (United States)

    Martin, Ambroise

    2010-01-01

    During the past decade, the use of claims became more and more important in many countries in relation to the increased awareness of consumer about the link between foods and health, offering to industry a valuable opportunity to differentiate and valorize their products and to promote innovation. However, more and more stringent regulations are developed, all based on the general principles adopted by the Codex Alimentarius Commission. In addition to the different regulatory processes and administrative requirements according to the country, the high level (and cost) of scientific substantiation of claims, the constraints introduced by nutrient profiles and the poor knowledge of the impact on consumer depending on the cultural contexts may limit these opportunities or, at least complicate their use. All these issues are briefly analyzed, highlighting some striking convergences and differences between countries.

  15. The Fourth Wave of Digitalization and Public Transport: Opportunities and Challenges

    Directory of Open Access Journals (Sweden)

    Paul Davidsson

    2016-11-01

    Full Text Available We investigate the opportunities and challenges of the forth wave of digitalization, also referred to as the Internet of Things (IoT, with respect to public transport and how it can support sustainable development of society. Environmental, economical, and social perspectives are considered through analysis of the existing literature and explorative studies. We conclude that there are great opportunities for both transport operators and planners, as well as for the travelers. We describe and analyze a number of concrete opportunities for each of these actors. However, in order to realize these opportunities, there are also a number of challenges that needs to be addressed. There are both technical challenges, such as data collection issues, interoperability, scalability and information security, and non-technical challenges such as business models, usability, privacy issues, and deployment.

  16. Knowledge as the Source of Opportunity

    DEFF Research Database (Denmark)

    Erikson, Truls; Korsgaard, Steffen

    2016-01-01

    In this paper, we show how Davidson's theory of knowledge can be used to elaborate the objective, intersubjective and subjective components of knowledge. Departing from Hayek's core insights about the dispersion of knowledge in society, we reiterate that opportunities involve subjective knowledge...... such as judgment and imagination, intersubjective knowledge of the social and institutional context, as well as knowledge about objective realities “out there”....

  17. HIV Vaccine-Challenges and Opportunities

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The need for an efficacious HIV/AIDS vaccine remains the highest priority of the world HIV/AIDS agenda. The generation of an efficacious HIV/AIDS vaccine proves an enormous scientific challenge. This article reviews the neutralizing antibody problem, elusive immune protection, immunogen design, pre-existing anti-vector immunity and design of phase 3 vaccine trials and the challenges and opportunities in development of HIV/AIDS vaccine are discussed.

  18. Cytogenomics of Feline Cancers: Advances and Opportunities

    OpenAIRE

    Rachael Thomas

    2015-01-01

    Relative to the dog, integration of the cat into the “One Health” concept has been more restricted, particularly in the field of molecular oncology. Beyond the continual need to enhance the sophistication of feline healthcare per se, the unique spectrum of naturally-occurring cancers in the cat offers tremendous opportunities for comparative and translational advances that may have mutual benefit for human and veterinary medicine. The study of feline cancers additionally may generate new insi...

  19. Grant opportunities for academic research and training

    Science.gov (United States)

    ,

    2016-08-30

    As an unbiased, multidisciplinary science organization, the U.S. Geological Survey (USGS) is dedicated to the timely, relevant, and impartial study of the health of our ecosystems and environment, our natural resources, the impacts of climate and land-use change, and the natural hazards that affect our lives. Grant opportunities for researchers and faculty to participate in USGS science through the engagement of students are available in the selected programs described in this publication.

  20. EMERGING CAPITAL MARKETS: OPPORTUNITIES AND LIMITS

    Directory of Open Access Journals (Sweden)

    FELICIA RAMONA BIRAU

    2012-05-01

    Full Text Available This theoretical study examines the concept of emerging capital markets in Europe from the border between certain opportunities and limits. The financial architecture of emerging capital markets has certain characteristics such as a high degree of instability and a sharp level of illiquidity which exposed the vulnerability of this particular type of market. Emerging capital market represents a main characteristic of developing countries and they are less efficient than the developed market given their deep functional, structural and institutional dysfunctions.

  1. Internships, employment opportunities, and research grants

    Science.gov (United States)

    ,

    2013-01-01

    As an unbiased, multidisciplinary science organization, the U.S. Geological Survey (USGS) is dedicated to the timely, relevant, and impartial study of the health of our ecosystems and environment, our natural resources, the impacts of climate and land-use change, and the natural hazards that threaten us. Opportunities for undergraduate and graduate students and faculty to participate in USGS science are available through the selected programs described below. Please note: U.S. citizenship is required for all government positions.

  2. Social Media and Orthopaedics: Opportunities and Challenges.

    Science.gov (United States)

    Suryavanshi, Tanishq; Geier, C David; Leland, J Martin; Silverman, Lance; Duggal, Naven

    2016-01-01

    Social media presents unique opportunities and challenges for practicing orthopaedic surgeons. Social media, such as blogging, Facebook, and Twitter, provides orthopaedic surgeons with a new and innovative way to communicate with patients and colleagues. Social media may be a way for orthopaedic surgeons to enhance communication with patients and healthcare populations; however, orthopaedic surgeons must recognize the limitations of social media and the pitfalls of increased connectedness in patient care.

  3. Crisis And Opportunities Of The Sales Networks

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    There have been disputes on the financial crisis upon the auto market in 2009.An expert held that the growth rate could stay at 5 percent. We do not have to argue whether the judgment is correct.There has been phi- losophy between crisis and opportunities. And if we adopt the logic in analyzing the sales networks,some detailed coun- termeasures can be worked out.

  4. Pollution prevention opportunity assessment for organization 1700.

    Energy Technology Data Exchange (ETDEWEB)

    Gerard, Morgan Evan

    2007-06-01

    This Pollution Prevention Opportunity Assessment (PPOA) was conducted for Sandia National Laboratories/New Mexico Organization 1700 in June, 2006. The primary purpose of this PPOA is to provide recommendations to assist Organization 1700 in reducing the generation of waste and improving the efficiency of their processes and procedures. This report contains a summary of the information collected, analyses performed and recommended options for implementation. The Sandia National Laboratories Pollution Prevention staff will continue to work with Organization 1700 to implement the recommendations.

  5. Future opportunities with pulsed neutron sources

    Energy Technology Data Exchange (ETDEWEB)

    Taylor, A.D. [Rutherford Appleton Lab., Chilton (United Kingdom)

    1996-05-01

    ISIS is the world`s most powerful pulsed spallation source and in the past ten years has demonstrated the scientific potential of accelerator-driven pulsed neutron sources in fields as diverse as physics, earth sciences, chemistry, materials science, engineering and biology. The Japan Hadron Project gives the opportunity to build on this development and to further realize the potential of neutrons as a microscopic probe of the condensed state. (author)

  6. Emerging opportunities: the internet, marketing and museums

    Directory of Open Access Journals (Sweden)

    Richani Evdoxia

    2016-01-01

    Full Text Available The tremendous impact of applying new technologies is obvious when it comes to museums. Internet forms an integral part of museums everyday life and decision making. Websites, online communities, social media, and mobile applications comprise elements of the modern museum’s digital self, which complements the real museum of permanent and temporary exhibitions, storage rooms, visitors’ facilities, laboratories and, most important, museum objects. This environment inevitably affects museum marketing strategies and creates relevant opportunities.

  7. Manufacturing With Lasers Developments and Opportunities

    Institute of Scientific and Technical Information of China (English)

    G. S. Booth

    2004-01-01

    Developments and opportunities for manufacturing with lasers are considered in three broad themes. Process enhancements, in particular hybrid-laser arc welding and twin spot laser welding are described. Two examples of novel manufacturing processes (laser joining of aluminium to steel and laser direct metal deposition) are considered. Finally, a new laser source (Yb: YAG fibre laser) is introduced as an additional competing processing capability.

  8. Convergence creates opportunities across health care system.

    Science.gov (United States)

    Fox, Brent I; Felkey, Bill G

    2014-04-01

    Industrial design students at Auburn do a creativity exercise where they are asked to combine a common household appliance with an animal. Have you seen a snake light? In health technology, we have a similar opportunity. In the connection between jewelry and vital sign monitoring technology or household security and health status monitoring, we are witnessing active convergence that will benefit patients, providers, and health systems.

  9. Thoracic surgery in India: challenges and opportunities

    OpenAIRE

    Yendamuri, Sai

    2016-01-01

    India has the dubitable honor of being ranked first in the world with regards to lung disease burden. A good proportion of this disease burden is amenable to surgical treatment. However, patients have limited access to quality thoracic surgical care due to a number of obstacles. This review article summarizes these obstacles and the implied opportunities that exist in this nascent surgical discipline in the world’s second most populous country.

  10. Thoracic surgery in India: challenges and opportunities.

    Science.gov (United States)

    Yendamuri, Sai

    2016-08-01

    India has the dubitable honor of being ranked first in the world with regards to lung disease burden. A good proportion of this disease burden is amenable to surgical treatment. However, patients have limited access to quality thoracic surgical care due to a number of obstacles. This review article summarizes these obstacles and the implied opportunities that exist in this nascent surgical discipline in the world's second most populous country.

  11. HIV testing in women: missed opportunities.

    Science.gov (United States)

    Duffus, Wayne A; Davis, Harley T; Byrd, Michael D; Heidari, Khosrow; Stephens, Terri G; Gibson, James J

    2012-02-01

    To investigate opportunities for early human immunodeficiency virus (HIV) testing of women. A retrospective cohort study design linked case reports from HIV surveillance to several statewide health-care databases. Medical encounters occurring before the first positive HIV test (missed opportunities) were categorized by diagnosis/procedure codes to distinguish visits that were likely to have prompted an HIV test. Women were categorized as late testers (AIDS diagnosis 12 months of HIV diagnosis), of reproductive age (13-44 years old), and not of reproductive age (>44 years old). Adjusted odds ratios (aOR) and 95% confidence intervals (CI) were used to estimate risk and its statistical significance. Of 3303 HIV-infected women diagnosed during the study period, 2408 (73%) had missed opportunity visits. Late testers (39%) were more likely to be black than white (aOR 1.48, 95% CI 1.12-1.95), be older (>44 years old; aOR 7.85, 95% CI 4.49-13.7), and have >10 missed opportunity visits (aOR 2.17, 95% CI 1.62-2.91). Fifty-four percent of women >44 years old were also late testers. Women >44 years old had lower median initial CD4 counts (p44 years old and Papanicolau smear was ranked fourth for late testers. Feasibility and acceptability of routine HIV testing in nontraditional health-care settings, such as mammography and Papanicolau screenings, should be explored to identify late testers and older (not of reproductive age) HIV-infected women.

  12. Technological Opportunities and New Firm Creation

    OpenAIRE

    Scott Shane

    2001-01-01

    Research on the creation of new high-technology companies has typically focused either on industry-level factors such as market structure and technology regime or on individual-level factors such as the work experience of entrepreneurs. This study complements these approaches by examining the effect of technological opportunities on firm formation. In particular, the study shows that the probability that an invention will be commercialized through firm formation is influenced by its importanc...

  13. Opportunity is a Two-Way Street

    Institute of Scientific and Technical Information of China (English)

    Ding Ying

    2011-01-01

    WITH a population of 900million and untouched natural resources,the continent of Africa has enormous economic potential.In a fast developing world hungry for resources many countries,around the globe,have their eyes on Africa,all keen to promote business connections.China is no exception and Chinese companies have provided a much-needed eco nomic boost and employment opportunities for many African countries in the recent past.

  14. Challenges and opportunities facing contractors in Ghana

    OpenAIRE

    Laryea, Samuel Amartei

    2010-01-01

    The main aim of this study was to ascertain and discuss the current challenges and opportunities facing construction contractors in Ghana. This involved a review of the economic, legal and political environments in which contractors in Ghana operate; a review of published studies on construction in developing countries generally and Ghana specifically; and in-depth interviews and discussions with seven building and civil engineering contractors in Ghana in 2009 and 2010. Six road contractors ...

  15. FINE-SCALE URBAN MODELING AND ITS OPPORTUNITIES IN THE "BIG DATA" ERA: METHODS, DATA AND EMPIRICAL STUDIES%大数据时代的精细化城市模拟:方法、数据和案例

    Institute of Scientific and Technical Information of China (English)

    龙瀛; 茅明睿; 毛其智; 沈振江; 张永平

    2014-01-01

    以地块作为基本空间单元并以城市活动主体作为模拟对象的精细化模拟是未来城市模型研究的重要方向,大数据(big data)时代的到来也为其提供了重要发展机遇.本文重点对精细化城市模型的主流建模方法进行了介绍,包括元胞自动机(Cellular Automata,CA)、基于主体建模(Agent-based Modelling,ABM)和传统的微观模拟(Microsimulation,MSM)这三种自下而上的微观模拟方法.之后结合精细化城市模型的高标准数据需求问题,对国际上通行的用于精细化模拟数据合成(population synthesis)的方法进行了综述,并给出笔者近年来在精细化城市模拟方面的多项实践案例,最后提出了以GIS为平台,结合CA/ABM/MSM方法,构建我国精细化城市模型的框架体系和关键技术,以期支持我国大城市地区空间政策的制定和评估.

  16. Education Reform and Equal Opportunity in Japan

    Directory of Open Access Journals (Sweden)

    Akito Okada

    2012-10-01

    Full Text Available Recently, there have been concerns that equality of educational opportunity has been lost and that this is leading to the stratification of Japanese society through the widening of income differentials, in a 'gap society'. In such a disparity society, secure full- time jobs are increasingly becoming limited to those who graduate from prestigious universities, and entry into those institutions is becoming connected more clearly with family income and investments. Parental attitudes towards their children taking extra lessons after school, going to cram schools, getting into university, and getting into a relatively highly-ranked university have influenced educational costs. This article examines the historical formation of the concept of equality of opportunity, which has been applied to the educational policy in Japan, particularly from the end of World War II to the new millennium. This paper also expands on the existing literature on educational policies in contemporary Japan by examining how the current educational reform efforts have affected equality of educational opportunity among children from different family backgrounds.

  17. Portfolio Analysis of Renewable Energy Opportunities: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Richards, Allison; Deprizio, Jodi; Anderson, Kate; DiOrio, Nick; Elgqvist, Emma; Simpkins, Travis

    2016-11-01

    Time Warner Cable (TWC), now Charter Communications (CC), partnered with the National Renewable Energy Laboratory (NREL) to assess the technical and economic potential for solar photovoltaic (PV), wind, and ground-source heat-pump systems at 696 TWC facilities. NREL identified 306 sites where adding a renewable energy system would provide cost savings over the project life-cycle. In general, the top sites have some combination of high electricity rates ($0.16-$0.29/kWh), significant state incentives, and favorable net-metering policies. If all projects were implemented via third-party power purchase agreements, TWC/CC would save $37 million over 25 years and meet 10.5% of their energy consumption with renewable energy. This paper describes the portfolio screening methodology used to identify and prioritize renewable energy opportunities across the TWC sites, as well as a summary of the potential cost savings that may be realized by implementing these projects. This may provide a template for other companies interested in identifying and prioritizing renewable energy opportunities across a large number of geographically dispersed sites. Following this initial portfolio analysis, NREL will be conducting in-depth analysis of project development opportunities at ten sites and evaluating off-grid solutions that may enable carbon emission reduction and grid independence at select facilities.

  18. Evolving Decision Rules to Predict Investment Opportunities

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    This paper is motivated by the interest in finding significant movements in financial stock prices. However, when the number of profitable opportunities is scarce, the prediction of these cases is difficult. In a previous work, we have introduced evolving decision rules (EDR) to detect financial opportunities. The objective of EDR is to classify the minority class (positive cases) in imbalanced environments. EDR provides a range of classifications to find the best balance between not making mistakes and not missing opportunities. The goals of this paper are: 1) to show that EDR produces a range of solutions to suit the investor's preferences and 2) to analyze the factors that benefit the performance of EDR. A series of experiments was performed. EDR was tested using a data set from the London Financial Market. To analyze the EDR behaviour, another experiment was carried out using three artificial data sets, whose solutions have different levels of complexity. Finally, an illustrative example was provided to show how a bigger collection of rules is able to classify more positive cases in imbalanced data sets. Experimental results show that: 1) EDR offers a range of solutions to fit the risk guidelines of different types of investors, and 2) a bigger collection of rules is able to classify more positive cases in imbalanced environments.

  19. Critical technologies research: Opportunities for DOE

    Energy Technology Data Exchange (ETDEWEB)

    1992-12-01

    Recent studies have identified a number of critical technologies that are essential to the nation's defense, economic competitiveness, energy independence, and betterment of public health. The National Critical Technologies Panel (NCTP) has identified the following critical technology areas: Aeronautics and Surface Transportation; Biotechnology and Life Sciences; Energy and Environment; Information and Communications; Manufacturing; and Materials. Sponsored by the Department of Energy's Office of Energy Research (OER), the Critical Technologies Research Workshop was held in May 1992. Approximately 100 scientists, engineers, and managers from the national laboratories, industry, academia, and govemment participated. The objective of the Berkeley Workshop was to advance the role of the DOE multiprogram energy laboratories in critical technologies research by describing, defining, and illustrating research areas, opportunities, resources, and key decisions necessary to achieve national research goals. An agenda was developed that looked at DOE's capabilities and options for research in critical technologies and provided a forum for industry, academia, govemment, and the national laboratories to address: Critical technology research needs; existing research activities and resources; capabilities of the national laboratories; and opportunities for national laboratories, industries, and universities. The Workshop included plenary sessions in which presentations by technology and policy leaders set the context for further inquiry into critical technology issues and research opportunities. Separate sessions then focused on each of the following major areas of technology: Advanced materials; biotechnology and life sciences; energy and environment; information and communication; and manufacturing and transportation.

  20. Critical technologies research: Opportunities for DOE

    Energy Technology Data Exchange (ETDEWEB)

    1992-12-01

    Recent studies have identified a number of critical technologies that are essential to the nation`s defense, economic competitiveness, energy independence, and betterment of public health. The National Critical Technologies Panel (NCTP) has identified the following critical technology areas: Aeronautics and Surface Transportation; Biotechnology and Life Sciences; Energy and Environment; Information and Communications; Manufacturing; and Materials. Sponsored by the Department of Energy`s Office of Energy Research (OER), the Critical Technologies Research Workshop was held in May 1992. Approximately 100 scientists, engineers, and managers from the national laboratories, industry, academia, and govemment participated. The objective of the Berkeley Workshop was to advance the role of the DOE multiprogram energy laboratories in critical technologies research by describing, defining, and illustrating research areas, opportunities, resources, and key decisions necessary to achieve national research goals. An agenda was developed that looked at DOE`s capabilities and options for research in critical technologies and provided a forum for industry, academia, govemment, and the national laboratories to address: Critical technology research needs; existing research activities and resources; capabilities of the national laboratories; and opportunities for national laboratories, industries, and universities. The Workshop included plenary sessions in which presentations by technology and policy leaders set the context for further inquiry into critical technology issues and research opportunities. Separate sessions then focused on each of the following major areas of technology: Advanced materials; biotechnology and life sciences; energy and environment; information and communication; and manufacturing and transportation.