WorldWideScience

Sample records for ophthalmology

  1. Personalized ophthalmology.

    Science.gov (United States)

    Porter, L F; Black, G C M

    2014-07-01

    Ophthalmology has been an early adopter of personalized medicine. Drawing on genomic advances to improve molecular diagnosis, such as next-generation sequencing, and basic and translational research to develop novel therapies, application of genetic technologies in ophthalmology now heralds development of gene replacement therapies for some inherited monogenic eye diseases. It also promises to alter prediction, diagnosis and management of the complex disease age-related macular degeneration. Personalized ophthalmology is underpinned by an understanding of the molecular basis of eye disease. Two important areas of focus are required for adoption of personalized approaches: disease stratification and individualization. Disease stratification relies on phenotypic and genetic assessment leading to molecular diagnosis; individualization encompasses all aspects of patient management from optimized genetic counseling and conventional therapies to trials of novel DNA-based therapies. This review discusses the clinical implications of these twin strategies. Advantages and implications of genetic testing for patients with inherited eye diseases, choice of molecular diagnostic modality, drivers for adoption of personalized ophthalmology, service planning implications, ethical considerations and future challenges are considered. Indeed, whilst many difficulties remain, personalized ophthalmology truly has the potential to revolutionize the specialty.

  2. Nordic research in ophthalmology

    DEFF Research Database (Denmark)

    Stefánsson, Einar; Zetterström, Charlotta; Ehlers, Niels

    2003-01-01

    Ophthalmology, eye research, cornea, catarcat, paediatric ophthalmology, glaucoma, diabetic eye disease, age-related macular degeneration, ophthalmic oncology......Ophthalmology, eye research, cornea, catarcat, paediatric ophthalmology, glaucoma, diabetic eye disease, age-related macular degeneration, ophthalmic oncology...

  3. Digital camera in ophthalmology

    Directory of Open Access Journals (Sweden)

    Ashish Mitra

    2015-01-01

    Full Text Available Ophthalmology is an expensive field and imaging is an indispensable modality in ophthalmology; and in developing countries including India, it is not possible for every ophthalmologist to afford slit-lamp photography unit. We here present our experience of slit-lamp photography using digital camera. Good quality pictures of anterior and posterior segment disorders were captured using readily available devices. It can be a used as a good teaching tool for residents learning ophthalmology and can also be a method to document lesions which at many times is necessary for medicolegal purposes. It's a technique which is simple, inexpensive, and has a short learning curve.

  4. Ophthalmology in Persian medicine.

    Science.gov (United States)

    Tabatabaei, Seyed Mahmoud; Sabetkish, Nastaran; Tabatabaei, Seyed Mohammad Ali

    2014-01-01

    Despite the fact that ophthalmology is one of the foremost branches of medicine, conceptualization of the structure and function of the eye barely advanced in ancient Western civilizations. At the early recovery of Persian civilization (9(th) century AD) after the extinction of the Sassanid Empire (7(th) century AD), translations of Greek medical textbooks played an important role in the development of medicine and the emergence of great Persian physicians such as Rhazes, Avicenna and others. Rhazes was a leading Persian physician whose medical teachings have as yet not been thoroughly explored. In addition to numerous books and articles in various fields, he authored a great medical Encyclopedia (al-Hawi al-Kabir) in 25 volumes. In this article, we are going to compare Rhazes' particular viewpoints about ophthalmology with those of other famous Persian physicians and some recent essays and textbooks. For this purpose we reviewed Rhazes' second volume of al-Hawi that is dedicated exclusively to ophthalmology and contains some major topics of ophthalmology including anatomy, physiology, pathology, diseases, disorders and treatments. Important themes were carefully extracted and compared with the tenets of modern ophthalmology. After collating Rhazes' viewpoints with the latest findings in this field, it was concluded that he had brilliantly written about the signs and symptoms, etiology and treatment of many eye disorders more than a thousand years ago. The amazing point is that there was no accurate equipment at the time to help him in his investigations. This study proved that Rhazes' theories conform to recent knowledge about ophthalmology in many aspects, and could therefore be the subject of further investigations.

  5. American Academy of Ophthalmology

    Science.gov (United States)

    ... Follow The Academy Professionals: Education Guidelines News Multimedia Public & Patients: Contact Us About the Academy Jobs at the Academy Financial Relationships with Industry Medical Disclaimer Privacy Policy Terms of Service For Advertisers For Media Ophthalmology Job Center © American Academy of ...

  6. Fee splitting in ophthalmology.

    Science.gov (United States)

    Levin, Alex V; Ganesh, Anuradha; Al-Busaidi, Ahmed

    2011-02-01

    Fee splitting and co-management are common practices in ophthalmology. These arrangements may conflict with the ethical principles governing the doctor-patient relationship, may constitute professional misconduct, and at times, may be illegal. Implications and perceptions of these practices may vary between different cultures. Full disclosure to the patient may minimize the adverse effects of conflicts of interest that arise from these practices, and may thereby allow these practices to be deemed acceptable by some cultural morays, professional guidelines, or by law. Disclosure does not necessarily relieve the physician from a potential ethical compromise. This review examines the practice of fee splitting in ophthalmology, its legal implications, the policies or guidelines governing such arrangements, and the possible ethical ramifications. A comparative view between 3 countries, Canada, the United States, and Oman, was conducted; illustrating that even in disparate cultures, there may be some universality to the application of ethical principles.

  7. Ophthalmology in Persian medicine

    OpenAIRE

    Tabatabaei, Seyed Mahmoud; Sabetkish, Nastaran; Tabatabaei, Seyed Mohammad Ali

    2014-01-01

    Despite the fact that ophthalmology is one of the foremost branches of medicine, conceptualization of the structure and function of the eye barely advanced in ancient Western civilizations. At the early recovery of Persian civilization (9th century AD) after the extinction of the Sassanid Empire (7th century AD), translations of Greek medical textbooks played an important role in the development of medicine and the emergence of great Persian physicians such as Rhazes, Avicenna and others. Rha...

  8. Lasers in Ophthalmology

    Institute of Scientific and Technical Information of China (English)

    1992-01-01

    In recent years,lasers have entered every fieldof medicine and especially so in ophthalmol-ogy.The scientific basis of lasers in ophthal-mology is based on three mechanisms:1.Photothermal effectLasers:argon,krypton,dye and diodeA thermal effect is generated when laserenergy is absorbed by pigment leading to in-creased vibration and therefore heat content.A

  9. Focused ultrasound in ophthalmology

    Directory of Open Access Journals (Sweden)

    Silverman RH

    2016-09-01

    Full Text Available Ronald H Silverman1,2 1Department of Ophthalmology, Columbia University Medical Center, 2F.L. Lizzi Center for Biomedical Engineering, Riverside Research, New York, NY, USA Abstract: The use of focused ultrasound to obtain diagnostically significant information about the eye goes back to the 1950s. This review describes the historical and technological development of ophthalmic ultrasound and its clinical application and impact. Ultrasound, like light, can be focused, which is crucial for formation of high-resolution, diagnostically useful images. Focused, single-element, mechanically scanned transducers are most common in ophthalmology. Specially designed transducers have been used to generate focused, high-intensity ultrasound that through thermal effects has been used to treat glaucoma (via cilio-destruction, tumors, and other pathologies. Linear and annular transducer arrays offer synthetic focusing in which precise timing of the excitation of independently addressable array elements allows formation of a converging wavefront to create a focus at one or more programmable depths. Most recently, linear array-based plane-wave ultrasound, in which the array emits an unfocused wavefront and focusing is performed solely on received data, has been demonstrated for imaging ocular anatomy and blood flow. While the history of ophthalmic ultrasound extends back over half-a-century, new and powerful technologic advances continue to be made, offering the prospect of novel diagnostic capabilities. Keywords: ophthalmic ultrasound, ultrasound biomicroscopy (UBM, high-intensity focused ultrasound (HIFU, ultrafast imaging, Doppler imaging 

  10. Nanotechnology in ophthalmology.

    Science.gov (United States)

    Zarbin, Marco A; Montemagno, Carlo; Leary, James F; Ritch, Robert

    2010-10-01

    Nanotechnology involves the creation and use of materials and devices at the size scale of intracellular structures and molecules, and involves systems and constructs in the order of nanotechnology as applied to nanomedicine (e.g., biomimicry and pseudointelligence). Some applications of nanotechnology to ophthalmology are described (including treatment of oxidative stress; measurement of intraocular pressure; theragnostics; use of nanoparticles to treat choroidal new vessels, prevent scarring after glaucoma surgery, and treat retinal degenerative disease with gene therapy; prosthetics; and regenerative nanomedicine). Nanotechnology will revolutionize our approach to current therapeutic challenges (e.g., drug delivery, postoperative scarring) and will enable us to address currently unsolvable problems (e.g., sight-restoring therapy for patients with retinal degenerative disease). Obstacles to the incorporation of nanotechnology remain, such as safe manufacturing techniques and unintended biological consequences of nanomaterial use. These obstacles are not insurmountable, and revolutionary treatments for ophthalmic diseases are expected to result from this burgeoning field.

  11. Gene therapy in ophthalmology.

    Science.gov (United States)

    Uthra, Satagopan; Kumaramanickavel, Govindasamy

    2009-09-01

    It has been more than a year since ophthalmologists and scientists under Dr. Robin Ali's team at the Moorsfield Eye Hospital and the Institute of Ophthalmology, University College London, successfully treated patients with a severely blinding disease, Leber's congenital amaurosis (LCA) using gene therapy. This success does not look to be transient, and this achievement in gene replacement therapy clinical trial for LCA has instilled hope in numerous families with patients suffering from this and similar retinal degenerative diseases, for whom restoration of lost vision has remained a distant dream so far. The encouragement that this success has given is expected to also lead to start of clinical trials for other blinding ocular diseases for which gene therapy experiments at the laboratory and animal levels have been successful. This article reviews the various studies that have led to the understanding of gene therapy outcomes in human ocular diseases and attempts to provide a brief sketch of successful clinical trials.

  12. Neuro-ophthalmology update.

    Science.gov (United States)

    Weber, Konrad P; Straumann, Dominik

    2014-07-01

    This review summarizes the most relevant articles from the field of neuro-ophthalmology published in the Journal of Neurology from January 2012 to July 2013. With the advent of video-oculography, several articles describe new applications for eye movement recordings as a diagnostic tool for a wide range of disorders. In myasthenia gravis, anti-Kv1.4 and anti-Lrp4 have been characterized as promising novel autoantibodies for the diagnosis of hitherto 'seronegative' myasthenia gravis. Several articles address new diagnostic and therapeutic approaches to neuromyelitis optica, which further sharpen its profile as a distinct entity. Additionally, 4-aminopyridine has become a standard therapeutic for patients with cerebellar downbeat nystagmus. Finally, revised diagnostic criteria have been proposed for chronic relapsing inflammatory optic neuropathy based on a careful literature review over the last decade.

  13. [Preservatives in ophthalmology].

    Science.gov (United States)

    Messmer, E M

    2012-11-01

    Preservatives are a legal requirement for eye drops in multidose containers. Moreover, they are necessary for stabilization and intraocular penetration for a number of ophthalmic preparations. Most preservatives act in a relatively unspecific manner as detergents or by oxidative mechanisms and thereby cause side effects at the ocular surface. They may also affect the lens, trabecular meshwork and the retina. Benzalkonium chloride is the most commonly used preservative in ophthalmology and is more toxic than other or newer preservatives, such as polyquaternium-1 (Polyquad), sodium perborate, oxychloro-complex (Purite®) and SofZia. Preservative-free topical medication is highly recommended for patients with ocular surface disease, frequent eye drop administration, proven allergy to preservatives and contact lens wear.

  14. Bioceramics in ophthalmology.

    Science.gov (United States)

    Baino, Francesco; Vitale-Brovarone, Chiara

    2014-08-01

    The benefits of ceramics in biomedical applications have been universally appreciated as they exhibit an extraordinarily broad set of physico-chemical, mechanical and biological properties which can be properly tailored by acting on their composition, porosity and surface texture to increase their versatility and suitability for targeted healthcare applications. Bioceramics have traditionally been used for the repair of hard tissues, such as bone and teeth, mainly due to their suitable strength for load-bearing applications, wear resistance (especially alumina, zirconia and composites thereof) and, in some cases, bone-bonding ability (calcium orthophosphates and bioactive glasses). Bioceramics have been also applied in other medical areas, like ophthalmic surgery; although their use in such a context has been scientifically documented since the late 1700s, the potential and importance of ceramic ocular implants still seem to be underestimated and an exhaustive, critical assessment is currently lacking in the relevant literature. The present review aims to fill this gap by giving a comprehensive picture of the ceramic-based materials and implants that are currently used in ophthalmology and pointing out the strengths and weaknesses of the existing devices. A prospect for future research is also provided, highlighting the potential of new, smart bioceramics able to carry specific added values which could have a significant impact on the treatment of ocular diseases.

  15. Gene therapy in ophthalmology

    Directory of Open Access Journals (Sweden)

    Satagopan Uthra

    2009-01-01

    Full Text Available It has been more than a year since ophthalmologists and scientists under Dr. Robin Ali′s team at the Moorsfield Eye Hospital and the Institute of Ophthalmology, University College London, successfully treated patients with a severely blinding disease, Leber′s congenital amaurosis (LCA using gene therapy. This success does not look to be transient, and this achievement in gene replacement therapy clinical trial for LCA has instilled hope in numerous families with patients suffering from this and similar retinal degenerative diseases, for whom restoration of lost vision has remained a distant dream so far. The encouragement that this success has given is expected to also lead to start of clinical trials for other blinding ocular diseases for which gene therapy experiments at the laboratory and animal levels have been successful. This article reviews the various studies that have led to the understanding of gene therapy outcomes in human ocular diseases and attempts to provide a brief sketch of successful clinical trials.

  16. The neuro-ophthalmological examination.

    Science.gov (United States)

    Rucker, Janet C; Kennard, Christopher; Leigh, R John

    2011-01-01

    The neuro-ophthalmological examination constitutes one of the most refined and exact components of the clinical examination, often allowing precise diagnosis and formulation of a treatment plan even within the compass of the first visit. This chapter briefly highlights important features in the neuro-ophthalmological history and then presents detailed information on the important components of a comprehensive neuro-ophthalmological examination. Covered examination topics include visual acuity, visual field testing, color vision, external eye exam, pupils, ophthalmoscopy, and eye movements. The final section discusses ancillary tests that supplement the bedside neuro-ophthalmological examination, including formal visual field analysis, electroretinography, fluorescein angiography, ocular coherence tomography, visual-evoked potentials, neuroimaging, and quantitative eye movement recordings. Copyright © 2011 Elsevier B.V. All rights reserved.

  17. Neuro-ophthalmology as a career.

    Science.gov (United States)

    Spitze, Arielle; Al-Zubidi, Nagham; Lam, Peter; Yalamanchili, Sushma; Lee, Andrew G

    2014-10-01

    This essay was written to discuss the reasoning behind the personal decisions made by 2 current neuro-ophthalmology fellows to pursue neuro-ophthalmology as a career. It is meant to enlighten the reader about what role neuro-ophthalmologists play in clinical practice, what makes neuro-ophthalmology unique to all other sub-specialties, and how this contributes to making neuro-ophthalmology not only one of the most medically interesting, yet rewarding sub-specialties in ophthalmology.

  18. CORRELATIONS BETWEEN OPHTHALMOLOGY AND ORTHOPEDICS.

    Science.gov (United States)

    Cazac, Cristian

    2015-01-01

    Although orthopedics and ophthalmology seem to be two different medical specialties, numerous studies that have been conducted in the past 35 years have shown a tight connection between several ocular pathologies and an increased risk of hip fractures due to falling. This article aims to review the ocular pathologies that have been proven to be associated with an increased risk of falling, to integrate the results of several studies showing a direct relationship between ocular pathologies and an increased risk of falling and finally to suggest ways in which the incidence of traumatic orthopedic injuries can be reduced by applying ophthalmologic principles.

  19. Neuro-ophthalmology as a career

    Directory of Open Access Journals (Sweden)

    Arielle Spitze

    2014-01-01

    Full Text Available This essay was written to discuss the reasoning behind the personal decisions made by 2 current neuro-ophthalmology fellows to pursue neuro-ophthalmology as a career. It is meant to enlighten the reader about what role neuro-ophthalmologists play in clinical practice, what makes neuro-ophthalmology unique to all other sub-specialties, and how this contributes to making neuro-ophthalmology not only one of the most medically interesting, yet rewarding sub-specialties in ophthalmology.

  20. OPHTHALMOLOGY

    African Journals Online (AJOL)

    Methods: A retrospective study of corneal ulcer patients treated between July 1998 and. June 2000. Results: One ... students, preschool children, traders, artisans and civil servants (p < 0.001). 66 eyes ... at the hospital. Materials and Methods.

  1. Tests for malingering in ophthalmology

    Directory of Open Access Journals (Sweden)

    Ali Ihsan Incesu

    2013-10-01

    Full Text Available Simulation can be defined as malingering, or sometimes functional visual loss (FVL. It manifests as either simulating an ophthalmic disease (positive simulation, or denial of ophthalmic disease (negative simulation. Conscious behavior and compensation or indemnity claims are prominent features of simulation. Since some authors suggest that this is a manifestation of underlying psychopathology, even conversion is included in this context. In today’s world, every ophthalmologist can face with simulation of ophthalmic disease or disorder. In case of simulation suspect, the physician’s responsibility is to prove the simulation considering the disease/disorder first, and simulation as an exclusion. In simulation examinations, the physician should be firm and smart to select appropriate test(s to convince not only the subject, but also the judge in case of indemnity or compensation trials. Almost all ophthalmic sensory and motor functions including visual acuity, visual field, color vision and night vision can be the subject of simulation. Examiner must be skillful in selecting the most appropriate test. Apart from those in the literature, we included all kinds of simulation in ophthalmology. In addition, simulation examination techniques, such as, use of optical coherence tomography, frequency doubling perimetry (FDP, and modified polarization tests were also included. In this review, we made a thorough literature search, and added our experiences to give the readers up-to-date information on malingering or simulation in ophthalmology.

  2. Misrepresentation by ophthalmology residency applicants.

    Science.gov (United States)

    Wiggins, Michael N

    2010-07-01

    To determine the percentage of publication misrepresentation among applicants to an ophthalmology residency, to compare that percentage with published percentages from other specialties, and to compare the number of US-trained applicants vs non-US-trained applicants found to misrepresent published articles. Published articles in peer-reviewed journals listed on residency applications to the Jones Eye Institute from October 10, 2000, to December 1, 2004, were searched, excluding applications that were unavailable or were from current residents and faculty. The type of misrepresentation of published articles and the country of medical school training were recorded. Compared were US-trained applicants vs non-US-trained applicants to determine which group was more likely to list published articles and which group was more likely to have a misrepresented published article. Eight hundred twenty-one of 852 applications (96.4%) were reviewed. Five hundred fifty applicants (67.0%) were from US medical schools, and 271 applicants (33.0%) were from non-US medical schools. Two hundred one applicants (24.5%) listed peer-reviewed published articles. Misrepresentation of published articles was found in 15 applicants (5 US trained and 10 non-US trained). The mean percentage of applicants with misrepresentation per applicant pool was 1.9%, while the mean percentage per applicants listing published articles was 8.1%. The most common misrepresentation found was self-promotion on the author list (50.0%), followed by omission of other authors (25.0%), nonexistent articles (12.5%), and nonauthorship (12.5%). Foreign medical graduates were more likely to list published articles (P = .008) and to have a misrepresented published article (P = .01). Ophthalmology has one of the lowest reported percentages of applicant publication misrepresentation in the literature. Foreign medical graduates were more likely to list published articles and to misrepresent published articles. Self-promotion on

  3. Curcumin: therapeutical potential in ophthalmology.

    Science.gov (United States)

    Pescosolido, Nicola; Giannotti, Rossella; Plateroti, Andrea Maria; Pascarella, Antonia; Nebbioso, Marcella

    2014-03-01

    Curcumin (diferuloylmethane) is the main curcuminoid of the popular Indian spice turmeric (Curcuma longa). In the last 50 years, in vitro and in vivo experiments supported the main role of polyphenols and curcumin for the prevention and treatment of many different inflammatory diseases and tumors.The anti-inflammatory, antioxidant, and antitumor properties of curcumin are due to different cellular mechanisms: this compound, in fact, produces different responses in different cell types. Unfortunately, because of its low solubility and oral bioavailability, the biomedical potential of curcumin is not easy to exploit; for this reason more attention has been given to nanoparticles and liposomes, which are able to improve curcumin's bioavailability. Pharmacologically, curcumin does not show any dose-limiting toxicity when it is administered at doses of up to 8 g/day for three months. It has been demonstrated that curcumin has beneficial effects on several ocular diseases, such as chronic anterior uveitis, diabetic retinopathy, glaucoma, age-related macular degeneration, and dry eye syndrome. The purpose of this review is to report what has so far been elucidated about curcumin properties and its potential use in ophthalmology.

  4. [Anesthesia in ophthalmology (author's transl)].

    Science.gov (United States)

    Gemperlé, M

    1977-02-01

    General anesthesia in ophthalmological surgery has become a great fashion. However there are still many problems especially in intraocular surgery. The eye with normal intraocular pressure generally needs no special technique. Most of the usual anesthesia produce a slight hypotonia with the exception of Succinylcholine, whose effect is contrary. Unfortunately this is not the case in eyes with pathologically increased intraocular pressure as in the different forms of glaucoma. Eye surgeons and anesthesists therefore look for solutions to this problem which in principle consist in the application of medicaments, which not seldom are rather agressive. The controlled hypotension by ganglion blockers, the curarisation in the state of being awake, the rapid perfusion of solutions with high osmotique effect (isolated or associated) represent such measures. The one has the disadvantage to be applied during so-called subvigile anesthesias where the security that the patient is asleep is rather doubtful; the other has the disadvantage that it requires a rapid perfusion of solutions with highly osmotic effect. It goes without saying that these conditions represent risks especially if one considers that the candidates for this type of intervention very often are senile persons with prearious cardiovascular equilibrium, with insufficient renal function and with insufficient arterial cerebral circulation. These are some of the problems which are to be discussed.

  5. OPHTHALMOLOGIC ABNORMALITIES IN CHILDREN WITH IMPAIRED HEARING

    OpenAIRE

    Inderjit; Jagdeepak; Prempal; Anup Narayanrao

    2014-01-01

    AIM: To determine the nature of ophthalmologic abnormalities in severe and profound grades of hearing impaired children and to treat visual impairment if any at the earliest . MATERIAL AND METHODS: Study was conducted on100 children in the age group of 5 - 14 years with severe and profound hearing loss visiting outpatient department of Ram Lal Eye and ENT hospital Govt. Medical College Amritsar and subjected to detailed ophthalmological examination. R...

  6. Integrating the Internship into Ophthalmology Residency Programs: Association of University Professors of Ophthalmology American Academy of Ophthalmology White Paper.

    Science.gov (United States)

    Oetting, Thomas A; Alfonso, Eduardo C; Arnold, Anthony; Cantor, Louis B; Carter, Keith; Cruz, Oscar A; Feldon, Steven; Mondino, Bartly; Parke, David W; Pershing, Suzann; Uhler, Tara; Volpe, Nicholas J

    2016-09-01

    Future ophthalmologists will need to have broad skills to thrive in complex health care organizations. However, training for ophthalmologists does not take advantage of all of the postgraduate years (PGYs). Although the traditional residency years seem to have little excess capacity, enhancing the internship year does offer an opportunity to expand the time for ophthalmology training in the same 4 PGYs. Integrating the internship year into residency would allow control of all of the PGYs, allowing our profession to optimize training for ophthalmology. In this white paper, we propose that we could capture an additional 6 months of training time by integrating basic ophthalmology training into the intern year. This would allow 6 additional months to expand training in areas such as quality improvement or time for "mini-fellowships" to allow graduates to develop a deeper set of skills.

  7. Trends in impact factors of ophthalmology journals

    Directory of Open Access Journals (Sweden)

    Igor Vainer

    2016-01-01

    Full Text Available Purpose: To test whether there is an association between the growth in the number of ophthalmic journals in the past years and their mean and maximum impact factor (IF as a common sign of scientific proliferation. Methods: Using data from the 2013 Journal Citation Report database a study of the major clinical medical fields was conducted to assess the correlation between the number of journals and maximum IF in a given field in the year 2013. In the field of ophthalmology, we examined the correlation between year, number of journals, mean IF and maximum IF in the field of ophthalmology throughout the years 2000–2013. Results: In the major medical fields, a positive correlation was found between the number of journals and the maximum IF (quadratic R2 = 0.71, P< 0.001. When studying the field of ophthalmology a positive correlation between the number of journals and mean IF (R2 = 0.84, P< 0.001 and between number of journals and maximum IF (R2 = 0.71, P< 0.001 was detected. Conclusions: Our findings suggest that the variation in the IF can be explained by the number of journals in the field of ophthalmology. In the future, the formation of additional ophthalmology journals is likely to further increase the IFs of existing journals.

  8. [Actively promote the development of neuro-ophthalmology in China].

    Science.gov (United States)

    Wei, Shi-hui; Zhao, Jia-liang

    2010-12-01

    Neuro-ophthalmology is a medical subspecialty concerned on the nervous system diseases with ocular manifestations, this could be both sensory and motor, including ocular movements, papillary responses, and the structure changes of the brain and nervous system with ocular manifestations. Although neuro-ophthalmology in China has achieved some progress, certain problems still exist, such as the professional neuro-ophthalmology team and related academic organization are still absent in China; neuro-ophthalmology knowledge has not been popularized; the new technologies for diagnosis and treatment in neuro-ophthalmology have not been absorbed and applied; the coordination and cooperation with other related disciplines are not enough. We should actively promote the development of neuro-ophthalmology in China, including organization of a professional team of neuro-ophthalmology, popularization of neuro-ophthalmology knowledge to the ophthalmologists, development of research work in neuro-ophthalmology and the collaboration with international neuro-ophthalmologists.

  9. Foundation of the American Academy of Ophthalmology

    Science.gov (United States)

    ... Follow The Academy Professionals: Education Guidelines News Multimedia Public & Patients: Contact Us About the Academy Jobs at the Academy Financial Relationships with Industry Medical Disclaimer Privacy Policy Terms of Service For Advertisers For Media Ophthalmology Job Center © American Academy of ...

  10. Cryotherapy in ophthalmology. Kryotherapie in der Augenheilkunde

    Energy Technology Data Exchange (ETDEWEB)

    Anders, M. (Medizinische Akademie Dresden (Germany))

    1993-01-01

    Ophthalmology is the only medical field in which all of the six known therapeutic applications of low temperature are used. The most important indications are discussed with reference to the corresponding device technology developed at the Department of Cryomedicine of the Dresden Academy of Medicine. (orig.)

  11. Optical Coherence Tomography (OCT) in ophthalmology: introduction.

    Science.gov (United States)

    Fujimoto, James G; Drexler, Wolfgang; Schuman, Joel S; Hitzenberger, Christoph K

    2009-03-02

    The Optical Society (OSA) is pleased to present this special issue of Optics Express on "Optical Coherence Tomography (OCT) in Ophthalmology" as part of the new Interactive Science Publishing (ISP) project. The project is being performed in collaboration with the National Library of Medicine and represents a new paradigm for the publication of digital image and large dataset information.

  12. Trends in impact factors of ophthalmology journals.

    Science.gov (United States)

    Vainer, Igor; Mimouni, Francis; Blumenthal, Eytan Z; Mimouni, Michael

    2016-09-01

    To test whether there is an association between the growth in the number of ophthalmic journals in the past years and their mean and maximum impact factor (IF) as a common sign of scientific proliferation. Using data from the 2013 Journal Citation Report database a study of the major clinical medical fields was conducted to assess the correlation between the number of journals and maximum IF in a given field in the year 2013. In the field of ophthalmology, we examined the correlation between year, number of journals, mean IF and maximum IF in the field of ophthalmology throughout the years 2000-2013. In the major medical fields, a positive correlation was found between the number of journals and the maximum IF (quadratic R2 = 0.71, Pjournals and mean IF (R2 = 0.84, Pjournals and maximum IF (R2 = 0.71, Pjournals in the field of ophthalmology. In the future, the formation of additional ophthalmology journals is likely to further increase the IFs of existing journals.

  13. Acquisition and retrieval of ophthalmology academic information

    Directory of Open Access Journals (Sweden)

    Lei Li

    2014-06-01

    Full Text Available This article discusses how to search and access ophthalmology information based on specialized websites and resources by introducing the database, search engines, electronic journals, electronic books and so on. Hope to help ophthalmic practitioners to carry out scientific research and clinical practice.

  14. [Development of ophthalmology in Bosnia and Herzegovina].

    Science.gov (United States)

    Masić, Izet; Alikadić-Husović, Amila; Milanović-Eichberger, Ljiljana

    2008-01-01

    Organized health services in Bosnia and Herzegovina started with the foundation of several vakuf hospitals (in Sarajevo, Tuzla, Banja Luka, Mostar and Travnik) financed by the fund of the Gazi Husrev-beg vakuf. In these hospitals services was provided by the qualified health professionals, mainly educated at the schools of medicine in Turkey, Italy, Austria, Hungary, Switzerland and other countries. Majority of them worked as civil and military physicians in the above mentioned vakuf hospitals, but also in the Turkey army hospitals situated in the all larger settlements in Bosnia and Herzegovina. During the period when B&H was managed by the Turkey and Austro-Hungarian empire there was no specialized ophthalmology services. During the Austro-Hungarian management there was a Surgical-oculist department within the Land Hospital in Sarajevo, which treated 4.47% of patients with eye diseases, among total number of in-patients, and according to the health service at the end of year 1900, during that year there there was 3238 general surgeries and 633 ophthalmology surgeries performed. In the Kingdom of Yugoslavia, beside establishment of the independent Eye department within the General State hospital in Sarajevo, in1923, also started development of the ophthalmology service within Surgical Department in Mostar, which was lead in 1929 by the ophthalmologist, and which grew in 1931 into independent Eye Department, as the second of that type in B&H. Specialized ophthalmology service in Banja Luka started to develop within the Surgery Department in 1931, and independent Eye Department was founded in 1945. Medical Faculty in Sarajevo was founded on 16th November 1946. Also on founded on the same day is the Eye Clinic, and appointed as its first director was Professor Vladimir Cavka MD., one of the first full time professors of the Medical Faculty in Sarajevo, founder of the Peoples society of B&H (Academy of Sciences and Arts of B&H) and the magazine, Medicinski arhiv

  15. Bevacizumab: Off-label use in ophthalmology

    Directory of Open Access Journals (Sweden)

    Grisanti Salvatore

    2007-01-01

    Full Text Available Bevacizumab is a full-length, humanized monoclonal antibody directed against all the biologically active isoforms of vascular endothelial growth factor (VEGF-A. The antibody was initially designed and studied as an anti-angiogenic strategy to treat a variety of solid tumors. After approval by the US Food and Drug Administration, bevacizumab gained access into ophthalmology to treat various types of neovascular diseases. Since the first report in 2005 more than 100 publications share the experience with bevacizumab in ophthalmology. Two authors independently assessed the research results from Pubmed to April 2007. The reference list is a selection of key publications related to the issue. Currently, there is no well-designed randomized controlled trial yet to establish the efficacy and safety of intraocular bevacizumab for any ocular disease in spite of its assumed characteristics representing the most cost-effective VEGF inhibitor.

  16. [Organizational ethics: a study in ophthalmologic clinics].

    Science.gov (United States)

    Sanches, Maria Aparecida; Scarpi, Marinho Jorge

    2005-01-01

    Research on the field of organizational ethics to investigate to which extent ophthalmologic clinics, inserted in the competitive atmosphere, in the condition of organizations in search of survival, subordinate ethics to competitiveness in the managerial praxis, that is, in the administrative sphere. Kohlberg is taken as theoretical reference, approaching the theme of ethical subordination to competitiveness. The instrument to evaluate moral behaviors of organizations, elaborated by Licht, is applied. The quantitative method is used, adopting analytic instruments, such as Q of Yule and non parametric tests, when dealing with the data of 41 ophthalmologic clinics. The results of the research seem to indicate that administrators of ophthalmologic clinics of greater performance subordinate ethical principles to competitiveness, seeking to assure the survival of the company and, when confronted with the instrument to evaluate their moral behavior, proposed by Kohlberg, have a significantly smaller presence in the postconventional stage than administrators of ophthalmologic clinics with a smaller performance. One may affirm, according to non parametric tests, at the level of significance of 0.05, that the levels of moral development of the two groups differ significantly. The obtained results are according to the literature, especially concerning the "paradox of the ethical subordination and competitiveness". They also suggest that the warrant of the survival of the company tends to reduce the perception of the groups in power regarding the problems that happen in the community, and that a reduction of the ethical values subordinated to competition occurs, and such reduction provokes growing feelings of economical disputes in the social sphere.

  17. The Use of Smart phones in Ophthalmology.

    Science.gov (United States)

    Zvornicanin, Edita; Zvornicanin, Jasmin; Hadziefendic, Bahrudin

    2014-06-01

    Smart phones are being increasingly used among health professionals. Ophthalmological applications are widely available and can turn smart phones into sophisticated medical devices. Smart phones can be useful instruments for the practice of evidence-based medicine, professional education, mobile clinical communication, patient education, disease self-management, remote patient monitoring or as powerful administrative tools. Several applications are available for different ophthalmological examinations that can assess visual acuity, color vision, astigmatism, pupil size, Amsler grid test and more. Smart phones can be useful ophthalmic devices for taking images of anterior and posterior eye segment. Professional literature and educational material for patients are easily available with use of smart phones. Smart phones can store great amount of informations and are useful for long term monitoring with caution for patient confidentiality. The use of smart phones especially as diagnostic tools is not standardized and results should be carefully considered. Innovative role of smartphone technology and its use in research, education and information sharing makes smart phones a future of ophthalmology and medicine.

  18. Worldwide geographical distribution of ophthalmology publications.

    Science.gov (United States)

    Guerin, Marc B; Flynn, Thomas H; Brady, Janice; O'Brien, Colm J

    2009-12-01

    International peer-reviewed publications form the basis of evidence-based medicine and are one of the main indicators of ophthalmology research activity. This paper examines the origins of such articles in relation to geographical location, population demographics and economic research profiles. Publications from five ophthalmology journals over 5 years were analysed using the Medline/Pubmed search engine. Country of origin was ascertained based on the address of the corresponding author. Worldwide ophthalmology research output was analysed in relation to population demographics and research expenditure. In total, 7,754 articles from 67 countries from 2002 to 2006 were analysed. The overall number of articles published increased by over 29% during this period. The United States (US) produced the greatest number of articles. Singapore produced the most publications per 10(6) population. There was a relationship between gross domestic product (GDP) greater than $20,000 and population-adjusted output. The US followed by the United Kingdom and Japan were the greatest gross contributors. Population-adjusted figures revealed that Singapore, Iceland and Australia were the most prolific nations. There was a relationship between GDP and the top-ranked population-adjusted countries. The top 10 most productive population-adjusted countries spend relatively more on research and development than the top 10 gross contributors.

  19. History and development of ophthalmology in Taiwan

    Directory of Open Access Journals (Sweden)

    Yu-Chih Hou

    2016-12-01

    Full Text Available Western medicine was first introduced to Taiwan by medical missionaries in the mid-19th century. Modernization of medicine was systematically transplanted to Taiwan in the Japanese colonial period, and ophthalmology was established third among hospital departments, following internal medicine and surgery. Dr Hidetaka Yamaguchi, an ophthalmologist, was the first head of the Taihoku Hospital, later known as National Taiwan University Hospital (NTUH; Taipei, Taiwan. Ophthalmologists during the colonial period conducted studies on tropical and infectious eye diseases. After World War II, ophthalmologists at NTUH played an important role in medical education, residency training, studies, and teaching. Dr Yan-Fei Yang established the Taiwan Ophthalmological Society in 1960 and instituted its official journal in 1962. Dr Ho-Ming Lin established the Department of Ophthalmology at the Tri-Service General Hospital in the 1950s and the Veterans General Hospital in the 1960s. Taiwan ophthalmologists eradicated trachoma by 1971. Cataract surgery and penetrating keratoplasty were initially performed in the 1960s. Currently, there are about 1600 ophthalmologists in Taiwan conducting an estimated 120,000 cataract surgeries and 600 corneal transplantations annually. Many subspecialty societies have been established recently that serve to educate Taiwanese ophthalmologists and to connect with international ophthalmic societies. Taiwan ophthalmologists continue to contribute to the advancement of ophthalmic knowledge globally.

  20. Feedback of final year ophthalmology postgraduates about their residency ophthalmology training in South India

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    K Ajay

    2014-01-01

    Full Text Available Background and Aims: This study documents a survey of final-year ophthalmology postgraduate students on the subject of their residency training. A similar survey conducted 7 years ago published in IJO had concluded that the residency program was not up to expectations in many centers. Our study aimed to see if ophthalmology training and student perceptions differed since then. Materials and Methods: For our study, we added a few questions to the same questionnaire used in the article "which is the best method to learn ophthalmology? Resident doctors′ perspective of ophthalmology training" published in IJO, Vol. 56 (5. Results: Forty-nine students (62.02% returned completed forms. Most students desired an orientation program on entering residency, and wished to undergo diagnostic training initially. Case-presentation with demonstration and Wet-lab learning were most preferred. There was a big difference between the number of surgeries students actually performed and the number they felt would have been ideal. Conclusion: On the whole, the students still felt the need for improved training across all aspects of ophthalmology.

  1. Appraisal of the retention of the knowledge for ophthalmology specialists of the Brazilian Ophthalmology Council

    Directory of Open Access Journals (Sweden)

    Limeira-Soares Paulo Henrique

    2006-01-01

    Full Text Available PURPOSE: To determine the retention of knowledge along the years after certification of physicians as ophthalmology specialists. METHODS: The physicians, former ophthalmology residents, were selected at the Department of Ophthalmology, State University of Campinas, São Paulo, Brazil, and randomly allocated to three groups of seven individuals, according to the time as specialists. Group 1 consisted of one-year specialists, group 2 of five-year specialists and group 3 of ten-year specialists. Each participant answered a test with twenty-five multiple choice randomly selected questions, based on the national certificate tests applied by the Brazilian Ophthalmology Council between 1994 and 2003. Each question scored four points. RESULTS: The mean age of groups 1, 2 and 3 was 27, 30 and 36 years, respectively. A preponderance of males was found in all groups. Group 1 achieved the highest score, average of 88, group 2 achieved 77, and group 3 achieved the lowest, average of 64 (p<0,05. CONCLUSION: Loss of knowledge retention amongst specialists of the Brazilian Ophthalmology Council, has been observed along the years after the certification.

  2. [Application of retinal oximeter in ophthalmology].

    Science.gov (United States)

    Li, Jing; Ma, Jianmin; Wang, Ningli

    2015-11-01

    Retinal oximeter is a new machine which has been used in the diagnose, treatment and research of several ophthalmic diseases for recent years. It allows ophthalmologists to gain retinal oxygen saturation directly. Therefore, retinal oximeter might be useful for ophthalmologists to understand ophthalmic diseases more deeper and clarify the impact of ischemia on retinal function. It has been reported in the literatures that retinal oximeter has potentially useful diagnostic and therapeutic indications in various eye diseases such as diabetic retinopathy, central retinal vein and artery occlusion, retinitis pigmentosa, glaucomatous optic neuropathy, et al. In this thesis, the application of retinal oximeter in ophthalmology is reviewed.

  3. Nevus of Ota: clinical-ophthalmological findings

    OpenAIRE

    Sebastião Cronemberger; Nassim Calixto; Henrique Leite Freitas

    2011-01-01

    OBJECTIVE: To analyze the clinical and ophthalmological findings of patients with nevus of Ota. METHODS: Retrospective analysis of patients' charts with nevus of Ota. We registered the demographic data, location of the nevus and date of appearance, family history of similar spots, biomicroscopic, gonioscopic, tonometric, ophthalmoscopic and perimetric findings. RESULTS: We included 14 patients, six (43.0%) men and eight (57.0%) women, with a mean age of 21.7±17.5 years. Ten (71%) were mulatt...

  4. Ophthalmologic identification of cerebral malaria in adults

    Directory of Open Access Journals (Sweden)

    Pedrosa, Catarina Areias

    2015-11-01

    Full Text Available Objective: To report the clinical presentation of malarial retinopathy in an adult, emphasizing the importance of this diagnosis for the clinical suspicion and prognosis of cerebral malaria. Methods: A 39-year-old caucasian man presented with hemolytic anemia, thrombocytopenia, acidemia and acute renal failure, developing severe encephalopathy. The diagnosis of malaria was done and after systemic stabilization, the patient noticed a central scotoma in the left eye. Ophthalmological examination revealed retinal features of malarial retinopathy. Results: At one-month follow-up, the patient had improved his systemic condition and the left eye scotoma had disappeared. Visual acuity was 20/20 in both eyes and on examination almost all lesions had regressed. Conclusion: Malarial retinopathy is a diagnostic factor and a prognosis indicator of severe infection, usually with brain involvement. The knowledge of the ophthalmological features associated with severe malaria, which is more frequent in children but can also occur in adults, becomes imperative in order to reduce the risk of neurologic sequelae and associated mortality.

  5. OPHTHALMOLOGIC ABNORMALITIES IN CHILDREN WITH IMPAIRED HEARING

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    Inderjit

    2014-02-01

    Full Text Available AIM: To determine the nature of ophthalmologic abnormalities in severe and profound grades of hearing impaired children and to treat visual impairment if any at the earliest . MATERIAL AND METHODS: Study was conducted on100 children in the age group of 5 - 14 years with severe and profound hearing loss visiting outpatient department of Ram Lal Eye and ENT hospital Govt. Medical College Amritsar and subjected to detailed ophthalmological examination. RESULTS: 100 children in the age group 5 - 14 years with hearing impairment were enrolled for t he study , 68 had profound and 32 had severe hearing loss . Visual disorders were found to be as high as 71%. Highest percentage was seen in children aged 7 years. Majority of them (50% had refractive error. Out of these 50 children , 28(56% had myopia , 10 (20% hypermetropia and 12(24% had astigmatism . The other ophthalmic abnormalities in our study were conjunctivitis 14(19.71% , fundus abnormalities and squint 11(15.49% , blepharitis 5 (7.04% , vitamin A deficiency 6 (8.04% , amblyopia 8 (11.26% , pupil disorder 3 (4.22% , cataract 3 (4.22% and heterochromia iridis 7 (9.85%. CONCLUSION : The high prevalence of ophthalmic abnormalities in deaf children mandate screening them for possible ophthalmic abnormalities. Early diagnosis and correction of visual d isturbances would go a long way in social and professional performance of these children.

  6. Ophthalmologic findings in contact sport disciplines.

    Science.gov (United States)

    Borrione, Paolo; Quaranta, Federico; DE Luca, Valeria; Sperandii, Fabio; Ciminelli, Emanuela; Cantera, Emilia; Fagnani, Federica; Pigozzi, Fabio

    2016-12-01

    The aim of the study was to investigate the prevalence and the incidence of ocular complications in contact sport disciplines in a large population of professional and amateur athletes over a period of 3 years. We performed a retrospective review of 694 medical records from athletes examinated from 2008 to 2011. The following data were collected during the routine visit for agonistic sports eligibility: medical history, age, weight, years of sport practice, approximate number of matches, head and eyes injuries during and beyond of the match and a through ocular history. All athletes underwent a detailed ophthalmological evaluation. The follow-up of each athlete was carried out during the following routine visit for agonistic sports eligibility. Most common disorders observed were: peripheral retinal degeneration, blepharitis, conjunctival and corneal diseases with a prevalence of 7%, 4%, 7% and 4% respectively. It was observed a positive correlation between peripheral retinal degeneration and age in amateur male boxers. Moreover, we noticed an incidence of 6% of laser therapeutic treatments as a result of retinal holes or degenerations, during the follow-up. Contact sport disciplines did not result in higher prevalence of severe ocular lesion. Both conjuntival diseases and peripheral retinal degenerations represented the ophthalmologic disorders with the higher prevalence in our sample. In particular, peripheral retinal degeneration is remarkable because of the increased risk of retinal detachment. Dyschromatopsie, even if quite rare, should be considered when analysing the reception of shots, since gloves in most cases are either red or blue.

  7. Breaking bad news: A communication competency for ophthalmology training programs.

    Science.gov (United States)

    Hilkert, Sarah M; Cebulla, Colleen M; Jain, Shelly Gupta; Pfeil, Sheryl A; Benes, Susan C; Robbins, Shira L

    As the ophthalmology accreditation system undergoes major changes, training programs must evaluate residents in the 6 core competencies, including appropriately communicating bad news. Although the literature is replete with recommendations for breaking bad news across various non-ophthalmology specialties, no formal training programs exist for ophthalmology. There are many valuable lessons to be learned from our colleagues regarding this important skill. We examine the historic basis for breaking bad news, explore current recommendations among other specialties, and then evaluate a pilot study in breaking bad news for ophthalmology residents. The results of this study are limited by a small number of residents at a single academic center. Future studies from multiple training programs should be conducted to further evaluate the need and efficacy of formal communication skills training in this area, as well as the generalizability of our pilot training program. If validated, this work could serve as a template for future ophthalmology resident training and evaluation in this core competency.

  8. Feasibility of photoacoustic tomography for ophthalmology

    Institute of Scientific and Technical Information of China (English)

    Tao Lu; Zhiyuan Song; Yixiong Su; Fan Zhang; Jianquan Yao

    2007-01-01

    For the eyeball composed of membrane and liquid, the contrast of ultrasound imaging is not high due to its small variance in acoustic impedance. As a new imaging modality, photoacoustic tomography combines the advantages of pure optical and ultrasonic imaging together and can provide high resolution, high contrast images. In this paper, the feasibility of photoacoustic tomography for ophthalmology is studied experimentally. A Q-switched Nd:YAG pulsed laser with 7-ns pulse width is used to generate photoacoustic signal of a porcine eyeball in vitro. The two-dimensional (2D) optical absorption image of the entire eyeball is reconstructed by time-domain spherical back projection algorithm. The imaging results agree well with the histological structure of the eyeball and show a high imaging contrast.

  9. "Eyes" on the thrones: imperial ophthalmologic nicknames.

    Science.gov (United States)

    Lascaratos, J

    1999-01-01

    Several Greek and Byzantine sovereigns are known in history by nicknames that are of ophthalmologic origin; the sobriquets derive from characteristics of their eyes or their actions in relation to the eyes. The first was Antigonos I Monophthalmus (the One-eyed), who was the most eminent successor of Alexander the Great and Sovereign of Eastern Mediterranean Asia. He obtained his nickname at an early age when he lost one eye fighting at the seige of Perinthos, as a general of King Philip of Macedon (father of Alexander the Great). Several Byzantine emperors also have a number of similar nicknames, such as Anastasius I Dicoros (with Heterochromia Iridis), Alexius V Ducas Murtzuphlus (with Scowling Eyebrows), and Andronicus I Comnenus Misophaes (Hater of Sunlight, since he blinded a great number of his opponents). To these must be added the Byzantine Empress Zoe Carvounopsina (with Coal-black Eyes).

  10. [Neuro-ophthalmological complications of sinusitis].

    Science.gov (United States)

    Tatuene, Joseph Kamtchum; Pollak, Pierre

    2013-10-01

    Sinusitis is a frequent and very often under-diagnosed condition. Despite the constantly increasing number of antibiotics with improved efficacy, prevention of its complications remains difficult. The prevalence of these complications is estimated at 3.7%. Their clinical presentation is highly variable making the diagnosis difficult and thereby increasing mortality. In this article, historical, epidemiological, pathophysiological, clinical and therapeutic aspects of neuro-ophthalmological complications of sinusitis are reviewed. For didactic reasons, the various complications have been divided into extra-axial, intra-axial, vascular, and orbital. Specific paragraph have been devoted to sinusitis-related bone complications and pain syndromes. It's however obvious that various more or less complex associations of these complications can be seen in daily practice.

  11. Paraneoplastic Syndromes in Neuro-Ophthalmology.

    Science.gov (United States)

    Gordon, Lynn K

    2015-09-01

    Paraneoplastic syndromes that affect the visual pathways and present with neuro-ophthalmologic signs or symptoms may involve the afferent or efferent systems. Afferent syndromes may involve the optic nerve or retina and, in some cases, these may be associated with systemic neurologic disease. Efferent symptoms typically affect eye movements and may involve the neuromuscular junction or involuntary eye movements. Literature review and personal clinical and research experience. Diagnosis of paraneoplastic syndromes relies on clinical and laboratory evaluations. In the appropriate clinical setting, the presence of specific antibodies may help confirm the diagnosis. In some cases, the visual pathway disturbance precedes a diagnosis of malignancy. Astute observation and selective evaluation and management are critical to establish the correct diagnosis and institute therapeutic approaches that can be sight or life saving.

  12. Experiences with E-learning in Ophthalmology

    Directory of Open Access Journals (Sweden)

    Seema Dutt Bandhu

    2014-01-01

    Full Text Available Introduction: E-learning is the use of internet for the purpose of education. E-learning in medical education is at a nascent stage in our country. The present study was carried out with the purpose of introducing e-learning to third year medical students in the subject of Ophthalmology and taking feedback on their attitude towards the new methodology of teaching and evaluating. Materials and Methods: E-learning was introduced to the seventh semester students of MBBS in the subject of Ophthalmology. The topics were converted to web friendly format and used for teaching and evaluating. Feedback was taken from the students on completion of the term on their attitudes towards e-learning and their views on the scope of e-learning in medical education. Results: All the students agreed on the usefulness of e-learning in medical education. Eleven students (27.5% found the medium of e-learning to be interesting, 15 (37.5% considered it to be easy and accessible, 10 (25% found it to be fast and easy, 4 (10% considered it to be a medium which can give updated information. Twenty-three (57.5% students considered that e-learning should be a medium of instruction in all the subjects, 15 (37.5% students considered its usefulness in clinical subjects only. Twenty-eight students (70% desired that e-learning should be used to provide important notes, questions, MCQs on all topics. Conclusions: E-learning is well accepted as a medium of instruction by medical students.

  13. Literature systematic review on the ophthalmological side effects of interferons

    Directory of Open Access Journals (Sweden)

    Yara Dadalti Fragoso

    2011-08-01

    Full Text Available Interferons alpha and beta have been used worldwide for a few decades, altering the natural history of several severe diseases including hepatitis C, cancer and immune-mediated conditions such as multiple sclerosis. The adverse events profile of interferons is well established, but only isolated reports of ophthalmological complications of interferon therapy have been published. The objective of this study was to carry out a literature systematic review on the subject, bringing to light the need for careful ophthalmological monitoring of patients undergoing interferon treatment. Nearly 500 cases of ophthalmological complications related to interferon have been reported. The most frequent findings were soft exudates, hemorrhages and retina ischemia.

  14. Dental Occlusion and Ophthalmology: A Literature Review

    Science.gov (United States)

    Marchili, Nicola; Ortu, Eleonora; Pietropaoli, Davide; Cattaneo, Ruggero; Monaco, Annalisa

    2016-01-01

    Stomatognathic system is strictly correlated to other anatomical regions; many studies investigated relationship between temporomandibular joint and posture, several articles describe cranio-facial pain from dental causes, such as trigger points. Until now less interest has been given to connections between dental occlusion and ophthalmology, even if they are important and involving. Clinical experience in dental practice claims that mandibular latero-deviation is connected both to eye dominance and to defects of ocular convergence. The trigeminal nerve is the largest and most complex of the twelve cranial nerves. The trigeminal system represents the connection between somitic structures and those derived from the branchial arches, collecting the proprioception from both somitic structures and oculomotor muscles. The intermedius nucleus of the medulla is a small perihypoglossal brainstem nucleus, which acts to integrate information from the head and neck and relays it on to the nucleus of the solitary tract where autonomic responses are generated. This intriguing neurophysiological web led our research group to investigate anatomical and functional associations between dental occlusion and vision. In conclusion, nervous system and functional pathways strictly connect vision and dental occlusion, and in the future both dentists and oculists should be more and more aware of this correlation for a better diagnosis and therapy. PMID:27733873

  15. [Hypercoagulable workup in ophthalmology. When and what].

    Science.gov (United States)

    Muñoz-Negrete, F J; Casas-Lleras, P; Pérez-López, M; Rebolleda, G

    2009-07-01

    Most ophthalmologic disorders secondary to hypercoagulabe state are due to the confluence of congenital and adquired factors. A systematic workup is mandatory. Most of congenital coagulation disorders cause venous trombosis and are inherited autosomal dominantly. In order of frequency these are factor V Leiden mutation (activated protein C resistance), G20210A mutation of the prothrombin gen and protein C, protein S, and antithrombin III deficiencies. Sickle cell anemia can determine arerial and venous thrombosis. In relation with arterial occlusion, the markers most frequently involved are homcysteine fasting levels and the markers of antiphospholipid antibody syndrome. Both of them can also determine venous thrombosis. Several acquired factors can lead to hypoercoagulable state, especially hyperhomocysteinemia, antiphospholipid antibody syndrome, hepatic disease, alcohol and tobacco intake, oral contraceptives, immobilization, surgeries and malignancies. In central venous occlusion is only necessary to rule out hyperhomocysteinemia and antiphospholipid antibody syndrome in young patients without known risk factors. In central artery occlusion, hypercoagulable workup is only recommended for patients less than 50 years-old with unknown emboli source. In this cases protein C, protein S, and antithrombin III deficiencies, homocystein, sickle cell disease and antiphospholipid antibody syndrome will ruled out. In non arteritic ischemic optic neuropathy hypercoagulable work up is not necessary. In amaurosis fugax without known emboli source, it is recommended to rule out etiologies of arterial occlusion, especially antithrombin III deficiencies, homocystein, sickle cell disease and antiphospholipid antibody syndrome.

  16. Use of Botulinum Neurotoxin in Ophthalmology

    Directory of Open Access Journals (Sweden)

    Emel Başar

    2016-12-01

    Full Text Available Botulinum neurotoxin (BoNT is the first biological toxin used in the treatment of ophthalmic diseases and to decrease skin wrinkles as an aesthetic agent. When used appropriately, it weakens the force of muscular contraction and/or inhibits glandular secretion. The most common areas for botulinum toxin treatment are the upper face, including the glabella, forehead, brows, and lateral canthal lines or crow’s feet. By relaxing the muscles causing wrinkles, non-permanent results may be achieved with its use. BoNT has gained widespread use in a variety of ophthalmic diseases. The effect of BoNT is temporary, but the therapeutic benefit is usually maintained even after repeated injections. Treatment is usually well tolerated. Complications and side effects associated with the treatment are rare and temporary. Complications occur due to weakness (chemodenervation of adjacent muscle groups, immunological mechanisms and injection technique. Current therapeutic indications, doses, complications and contraindications of BoNT use in the following disorders related to ophthalmology were investigated: aesthetic use, strabismus, blepharospasm, hemifacial spasm, eyelid retraction, entropion, lacrimal hypersecretion syndrome, and facial paralysis.

  17. Use of Botulinum Neurotoxin in Ophthalmology

    Science.gov (United States)

    Başar, Emel; Arıcı, Ceyhun

    2016-01-01

    Botulinum neurotoxin (BoNT) is the first biological toxin used in the treatment of ophthalmic diseases and to decrease skin wrinkles as an aesthetic agent. When used appropriately, it weakens the force of muscular contraction and/or inhibits glandular secretion. The most common areas for botulinum toxin treatment are the upper face, including the glabella, forehead, brows, and lateral canthal lines, or crow’s feet. By relaxing the muscles causing wrinkles, non-permanent results may be achieved with its use. BoNT has gained widespread use in a variety of ophthalmic diseases. The effect of BoNT is temporary, but the therapeutic benefit is usually maintained even after repeated injections. Treatment is usually well tolerated. Complications and side effects associated with the treatment are rare and temporary. Complications occur due to weakness (chemodenervation) of adjacent muscle groups, immunological mechanisms and injection technique. Current therapeutic indications, doses, complications and contraindications of BoNT use in the following disorders related to ophthalmology were investigated: aesthetic use, strabismus, blepharospasm, hemifacial spasm, eyelid retraction, entropion, lacrimal hypersecretion syndrome, and facial paralysis. PMID:28050326

  18. What is new in Recommendations on Ophthalmological Screening ...

    African Journals Online (AJOL)

    2017-09-14

    Sep 14, 2017 ... and in connective tissue disorders such as systemic lupus erythematosus, rheumatoid arthritis, juvenile idiopathic arthritis ... paper systematizes the information on ophthalmological screening in chloroquine derivatives users.

  19. COMPUTER LEARNING SIMULATOR WITH VIRTUAL REALITY FOR OPHTHALMOLOGY

    Directory of Open Access Journals (Sweden)

    Valeria V. Gribova

    2013-01-01

    Full Text Available A toolset of a medical computer learning simulator for ophthalmology with virtual reality and its implementation are considered in the paper. The simulator is oriented for professional skills training for students of medical universities. 

  20. [Emphasis on the application of precision medicine in ophthalmology].

    Science.gov (United States)

    Sun, X D; Zhu, H

    2016-02-01

    Accompany with dramatically growth of large-scale biological databases (such as human genome sequence), improvement of life science and development of international clinical trials, science offers great potential for improving health care through precision medicine. As a hot topic recently, precision medicine might launch a revolution of the methodology in medical research. How to achieve precision medicine in clinical ophthalmology by means of biological data mining is a challenge for ophthalmologist-scientists. The best approach for advanced individual medicine is to buildup the digital ophthalmology, which includes human eye biobank, national biological databases network, clinical department, basic research lab, and international clinical trial center. The system of digital ophthalmology could explore the methods for ophthalmology research, integrate the source of eye biologic databases, promote international cooperation, and thus eventually supply the opportunity for translational medicine.

  1. Antonio Scarpa (1752-1832): father of Italian ophthalmology.

    Science.gov (United States)

    Grzybowski, Andrzej

    2014-01-01

    Antonio Scarpa (1752-1832) was a prominent scholar who contributed greatly to otolaryngology, orthopedics, ophthalmology, neuroanatomy, and surgery. In 1801, he published a textbook on ophthalmology, the first Italian textbook on this subject and the most propagated European ophthalmic textbook in the first half of the 19th century. The book included important descriptions of lacrimal system disorders, many oculoplastic procedures, and the first description of posterior staphyloma.

  2. Clinical trials in Brazilian journals of ophthalmology: where we are.

    Science.gov (United States)

    Lira, Rodrigo Pessoa Cavalcanti; Leal, Franz Schubert; Gonçalves, Fauze Abdulmassih; Amorim, Fernando Henrique Ramos; Felix, João Paulo Fernandes; Arieta, Carlos Eduardo Leite

    2013-01-01

    To compare clinical trials published in Brazilian journals of ophthalmology and in foreign journals of ophthalmology with respect to the number of citations and the quality of reporting [by applying the Consolidated Standards for Reporting Trials (CONSORT) statement writing standards]. The sample of this systematic review comprised the two Brazilian journals of ophthalmology indexed at Science Citation Index Expanded and six of the foreign journals of ophthalmology with highest Impact Factor® according ISI. All clinical trials (CTs) published from January 2009 to December 2010 at the Brazilians journals and a 1:1 randomized sample of the foreign journals were included. The primary outcome was the number of citations through the end of 2011. Subgroup analysis included language. The secondary outcome included likelihood of citation (cited at least once versus no citation), and presence or absence of CONSORT statement indicators. The citation counts were statistically significantly higher (Pjournals of ophthalmology still are low when compared with the foreign journals of ophthalmology with highest Impact Factor®.

  3. Nevus of Ota: clinical-ophthalmological findings

    Directory of Open Access Journals (Sweden)

    Sebastião Cronemberger

    2011-10-01

    Full Text Available OBJECTIVE: To analyze the clinical and ophthalmological findings of patients with nevus of Ota. METHODS: Retrospective analysis of patients' charts with nevus of Ota. We registered the demographic data, location of the nevus and date of appearance, family history of similar spots, biomicroscopic, gonioscopic, tonometric, ophthalmoscopic and perimetric findings. RESULTS: We included 14 patients, six (43.0% men and eight (57.0% women, with a mean age of 21.7±17.5 years. Ten (71% were mulatto, three (21.4% white and one (7.1% black. Twelve (85.7% patients presented the spots at birth and two in puberty. Nine patients presented conjunctival and episcleral pigmentation in the right eye and five in the left eye. According to Tanino's classification, five (35.7% nevi were class 1, eight (57.1% class 2 and one (7.1% class 3. Heterochromia iridis was found in eight (57.1% patients. Anisocoria was present in three (21.4% patients. Five (35.7% patients presented a suspected glaucomatous cup disc ratio (≥0.7; six (42.9% presented a cup disc ratio ≤ 0.5 and three (21.4%, no cup disc. We found two curious and remarkable findings: a nevus of Ota on the palate of one patient and other on the optic disc associated with a pigmentary mottling of the fundus in another patient. The pigmentary mottling of the fundus was also seen in four more eyes. CONCLUSIONS: The nevus of Ota was frequently present at birth, in mulattos, and classified as Tanino's class 1 and 2. Heterochromia iridis was a common finding. Anisocoria was present in a small percentage of eyes. No patient developed glaucoma or malignancy.

  4. Self-citation rate and impact factor in ophthalmology.

    Science.gov (United States)

    Mimouni, Michael; Segal, Ori

    2014-01-01

    To analyze the self-citation rate (SCR) of ophthalmology journals, determine its possible effect on a journal's impact factor (IF) and compare the SCR of subspecialty journals versus general ophthalmology journals. A retrospective consecutive study of ophthalmology journals listed in the Journal Citations Report (JCR) 2013. We retrieved these parameters from each journal's report: IF, total citations, self-citations, SCR and IF without self-citations (corrected IF). A significant correlation was detected between the number of self-citations and publications (R(2) = 86.3, p = 0.000). Subspecialty journals had a significantly higher SCR than general journals (p = 0.017). No significant difference was found in terms of IF and corrected IF between general and subspecialty journals (p = 0.260 and p = 0.108, respectively). No significant correlation between IF and SCR was detected (p = 0.099). The corrected IF was inversely correlated with SCR (R(2) = -32.6, p = 0.013). An inverse correlation was detected between SCR and IF in the 29 ophthalmology journals with the lowest IF (R(2) = -57.3, p = 0.001). Unlike other fields of medicine, the IF of an ophthalmology journal does not correlate with its SCR. Self-citation is found more often in journals with a low corrected IF and is inversely correlated with IF in the bottom half. © 2014 S. Karger AG, Basel.

  5. Clinical trials in Brazilian journals of ophthalmology: where we are

    Directory of Open Access Journals (Sweden)

    Rodrigo Pessoa Cavalcanti Lira

    2013-02-01

    Full Text Available PURPOSE: To compare clinical trials published in Brazilian journals of ophthalmology and in foreign journals of ophthalmology with respect to the number of citations and the quality of reporting [by applying the Consolidated Standards for Reporting Trials (CONSORT statement writing standards]. METHODS: The sample of this systematic review comprised the two Brazilian journals of ophthalmology indexed at Science Citation Index Expanded and six of the foreign journals of ophthalmology with highest Impact Factor® according ISI. All clinical trials (CTs published from January 2009 to December 2010 at the Brazilians journals and a 1:1 randomized sample of the foreign journals were included. The primary outcome was the number of citations through the end of 2011. Subgroup analysis included language. The secondary outcome included likelihood of citation (cited at least once versus no citation, and presence or absence of CONSORT statement indicators. RESULTS: The citation counts were statistically significantly higher (P<0.001 in the Foreign Group (10.50 compared with the Brazilian Group (0.45. The likelihood citation was statistically significantly higher (P<0.001 in the Foreign Group (20/20 - 100% compared with the Brazilian Group (8/20 - 40%. The subgroup analysis of the language influence in Brazilian articles showed that the citation counts were statistically significantly higher in the papers published in English (P<0.04. Of 37 possible CONSORT items, the mean for the Foreign Group was 20.55 and for the Brazilian Group was 13.65 (P<0.003. CONCLUSION: The number of citations and the quality of reporting of clinical trials in Brazilian journals of ophthalmology still are low when compared with the foreign journals of ophthalmology with highest Impact Factor®.

  6. [Developments and inventions from Germany : Influence on international ophthalmology].

    Science.gov (United States)

    Müller, M; Pavlovic, I; Schmack, I; Ohrloff, C; Kohnen, T

    2017-07-24

    There are various developments and inventions from Germany that have influenced not only the domestic but also the international field of ophthalmology. Beginning with the invention of the ophthalmoscope by Hermann von Helmholtz in 1850, to the establishment of the "Archives of Ophthalmology" medical journal, a publication founded by Albrecht von Graefe in 1854, through to the development of the retinal chip by Eberhart Zrenner and colleagues with the first clinical data collected in 2007. The abovenamed and further developments and the German ophthalmologists behind these inventions are discussed in more detail.

  7. Application of smart phone on interactive teaching methods in ophthalmology

    Directory of Open Access Journals (Sweden)

    Xiao-Li Ma

    2016-06-01

    Full Text Available Smart phones as a symbol of the mobile Internet appears in college classroom, which is not only a challenge, but also a great opportunities of education information. This paper applied smart phones as the carrier of the "Internet" into ophthalmology classroom. Smart phones has a lot of features, such as rich teaching resources, diverse learning methods, flexible learning time, collating and recording capabilities and the timely, comprehensive and accurate teaching feedback so on, and could be used in case teaching and interactive teaching. The implementation of smart phones into ophthalmology classroom could inspire the learning enthusiasm of the students, enhance the quality of teaching, eventually improve teaching effects.

  8. Chiasmal syndrome. Ophthalmological and neuro-radiological aspects

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    van Dalen, J.T.W.; Verbeeten, B.J.W.M.; Peeters, F.L.M. (Amsterdam Univ. (Netherlands). Oogheelkundig Inst.)

    1982-01-29

    The chiasmal syndrome has distinct ophthalmological features such as visual field loss, optic disc changes, decrease in visual acuity, ocular motor disturbances and exophthalmos. However, the pathological processes in the chiasmal region often give rise to differential diagnostic problems. Before the era of computer tomography (CT) these processes could only be visualized by means of indirect or invasive examination techniques. After introduction of computer tomography these processes could be identified much more easily. The ophthalmological findings are discussed. The most frequent causes of chiasmal syndrome are demonstrated on CT scan. The neuro-radiological differential diagnosis of an enlarged sella turcica is given.

  9. 3D Printing: Print the future of ophthalmology.

    Science.gov (United States)

    Huang, Wenbin; Zhang, Xiulan

    2014-08-26

    The three-dimensional (3D) printer is a new technology that creates physical objects from digital files. Recent technological advances in 3D printing have resulted in increased use of this technology in the medical field, where it is beginning to revolutionize medical and surgical possibilities. It is already providing medicine with powerful tools that facilitate education, surgical planning, and organ transplantation research. A good understanding of this technology will be beneficial to ophthalmologists. The potential applications of 3D printing in ophthalmology, both current and future, are explored in this article. Copyright 2014 The Association for Research in Vision and Ophthalmology, Inc.

  10. Research productivity of Canadian ophthalmology departments in top 10 ophthalmology and vision science journals from 2001 to 2010.

    Science.gov (United States)

    Schlenker, Matthew B; Manalo, Elbert; Wong, Agnes M F

    2013-02-01

    To evaluate the research productivity of Canadian ophthalmology departments in terms of research volume, impact, funding, and cost-efficiency, and compare these measures with the top 6 U.S. departments. Systemic review. Using the Web of Science, we obtained the number of peer-reviewed research articles and citations in which an author listed an ophthalmology department (or affiliated university or hospital) from 2001 to 2010 in the top 10 ophthalmology and vision sciences journals, as well as the Canadian Journal of Ophthalmology. Federal research funding received from the Canadian Institutes of Health Research and National Institutes of Health was also obtained. The 3 universities that produced the highest number of articles were the University of Toronto (UofT), McGill University, and the University of British Columbia (UBC). UofT also produced the largest number of citations, followed by UBC and Dalhousie University. For the number of citations per article, the top 3 were the University of Ottawa, Dalhousie University, and the University of Calgary. McGill University, the University of Montreal, and UofT received the most federal funding. The 3 Canadian universities with the lowest funding (cost) per article were UofT, UBC, and McMaster University. The top contributors to the Canadian Journal of Ophthalmology from 2001 to 2010 were UofT, the University of Ottawa, and McGill University. Larger Canadian departments tended to generate higher research volume and obtained more federal funding, but smaller departments also contributed significantly, and sometimes surpassed larger departments, in terms of research impact and cost-efficiency. The top 6 U.S. departments generated higher research volume and received more federal research funding than their Canadian counterparts. However, when research impact and cost-efficiency were examined, Canadian departments performed similar to the top U.S. departments. Copyright © 2013 Canadian Ophthalmological Society. Published

  11. Teaching and Assessing Systems-based Competency in Ophthalmology Residency Training Programs

    NARCIS (Netherlands)

    Lee, Andrew G.; Beaver, Hilary A.; Greenlee, Emily; Oetting, Thomas A.; Boldt, H. Culver; Olson, Richard; Abramoff, Michael; Carter, Keith

    2007-01-01

    The Accreditation Council for Graduate Medical Education (ACGME) has mandated that residency programs, including ophthalmology, teach and assess specific competencies, including systems-based learning. We review the pertinent literature on systems-based learning for ophthalmology and recommend speci

  12. Primary headache disorders and neuro-ophthalmologic manifestations

    Directory of Open Access Journals (Sweden)

    Schwartz DP

    2012-09-01

    Full Text Available Daniel P Schwartz, Matthew S RobbinsDepartment of Neurology, Montefiore Headache Center, Albert Einstein College of Medicine, Bronx, NY, USAAbstract: Headache is an extraordinarily common complaint presenting to medical practitioners in all arenas and specialties, particularly primary care physicians, neurologists, and ophthalmologists. A wide variety of headache disorders may manifest with a myriad of neuro-ophthalmologic symptoms, including orbital pain, disturbances of vision, aura, photophobia, lacrimation, conjunctival injection, ptosis, and other manifestations. The differential diagnosis in these patients is broad and includes both secondary, or symptomatic, and primary headache disorders. Awareness of the headache patterns and associated symptoms of these various disorders is essential to achieve the correct diagnosis. This paper reviews the primary headache disorders that prominently feature neuro-ophthalmologic manifestations, including migraine, the trigeminal autonomic cephalalgias, and hemicrania continua. Migraine variants with prominent neuro-ophthalmologic symptoms including aura without headache, basilar-type migraine, retinal migraine, and ophthalmoplegic migraine are also reviewed. This paper focuses particularly on the symptomatology of these primary headache disorders, but also discusses their epidemiology, clinical features, and treatment.Keywords: headache, migraine, trigeminal autonomic cephalalgias, neuro-ophthalmologic, aura, photophobia

  13. [Establishment of diagnosis and treatment patterns of holistic integrated medicine for neuro-ophthalmology].

    Science.gov (United States)

    Wang, Yanling

    2014-12-01

    Neuro-ophthalmology, as an interdisciplinary, covers at least three disciplines- ophthalmology, neurology and neurosurgery. With limited knowledge in each discipline, doctors often make misdiagnoses for neuro-ophthalmology diseases. Therefore, it is imperative to abandon the distinction between disciplines and combine all the knowledge to diagnose and treat patients in patterns of holistic integrated medicine in order to effectively improve the diagnosis and treatment of neuro-ophthalmology.

  14. [To strengthen the education on basic knowledge and skills of neuro-ophthalmology].

    Science.gov (United States)

    Zhang, Xiao-jun; Wang, Ning-li

    2011-12-01

    Basic knowledge and skills are cornerstone of the diagnosis and treatment of neuro-ophthalmology diseases in ophthalmology practice. Due to the interdisciplinary features of neuro-ophthalmology, neuro-anatomy, neuro-physiology related to eyes, neuro-image and neuro-electrodiagnosis, these should be included in the education for the ophthalmologist. Special attention should be paid to training on capability of logically thinking in neuro-ophthalmology. Multiple ways can be used for the education of ophthalmologists and neurologists for the enhancement of basic knowledge and skills of neuro-ophthalmology in China.

  15. [Applications of optical coherence tomography (OCT) in neuro-ophthalmology].

    Science.gov (United States)

    Kernstock, C; Friebe, K; Tonagel, F

    2013-11-01

    Optical coherence tomography (OCT) has revolutionised ophthalmology. Due to modern instruments with extremely high resolution there are more and more applications also in neuro-ophthalmological disorders. This review gives an overview on typical changes in OCT for the following diseases: autosomal dominant optic atrophy, Leber hereditary optic neuropathy, toxic, traumatic and compressive optic neuropathy, optic nerve drusen, anterior ischaemic optic neuropathy, optic disc pit, papilledema, optic neuritis (isolated or associated with multiple sclerosis or neuromyelitis optica), neurodegenerative diseases and hereditary retinal diseases. A diagnosis exclusively based on an OCT examination is not always possible, but in several diseases there are pathognomonic changes that directly lead to the correct diagnosis. Particularly with the often complex settings in neuro-ophtalmology the OCT should be seen as a supplementary modality and not as a replacement for other techniques.

  16. Iontophoresis in ophthalmology: A review of the literature

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    Naser Shoeibi

    2014-07-01

    Full Text Available Drug delivery to the inner part of the eye is still a problem in treatment of ocular disease. Iontophoresis has been used in the field of medicine for many years. This technique consists of applying a weak electrical current to drive charged drug molecules across tissue barriers. Transcorneal iontophoresis delivers a high concentration of drug to the anterior segment of the eye (cornea, aqueous humor, ciliary body, iris, and lens, for the treatment of anterior segment diseases. There are different types of iontophoresis such as ophthalmic, transdermal, transungual, oral, buccal, and transnasal. The benefit of iontophoretic drug delivery in ophthalmology lays in its capacity to provide high drug tissue concentration safely, while minimizing the systemic drug exposure. This review summarizes basics of ocular iontophoresis and iontophoretic device, trans corneal and transscleral iontophoresis, and the applications of iontophoresis in ophthalmology.

  17. Clinical safety and professional liability claims in Ophthalmology.

    Science.gov (United States)

    Dolz-Güerri, F; Gómez-Durán, E L; Martínez-Palmer, A; Castilla Céspedes, M; Arimany-Manso, J

    2017-06-29

    Patient safety is an international public health priority. Ophthalmology scientific societies and organisations have intensified their efforts in this field. As a tool to learn from errors, these efforts have been linked to the management of medical professional liability insurance through the analysis of claims. A review is performed on the improvements in patient safety, as well as professional liability issues in Ophthalmology. There is a high frequency of claims and risk of economic reparation of damage in the event of a claim in Ophthalmology. Special complaints, such as wrong surgery or lack of information, have a high risk of financial compensation and need strong efforts to prevent these potentially avoidable events. Studies focused on pathologies or specific procedures provide information of special interest to sub-specialists. The specialist in Ophthalmology, like any other doctor, is subject to the current legal provisions and appropriate mandatory training in the medical-legal aspects of health care is essential. Professionals must be aware of the fundamental aspects of medical professional liability, as well as specific aspects, such as defensive medicine and clinical safety. The understanding of these medical-legal aspects in the routine clinical practice can help to pave the way towards a satisfactory and safe professional career, and help in increasing patient safety. The aim of this review is to contribute to this training, for the benefit of professionals and patients. Copyright © 2017 Sociedad Española de Oftalmología. Publicado por Elsevier España, S.L.U. All rights reserved.

  18. Novel use of smart tablet computer for ophthalmology

    Directory of Open Access Journals (Sweden)

    Zhao-Tian Zhang

    2015-01-01

    Full Text Available AIM:To identify and categorize ophthalmology-relevant apps for the iPad tablet computer as a source for ophthalmic practices on the Apple's App Store.METHODS: The Apple's App Store was searched for ophthalmology-relevant apps from January 2013 to August 2013. Eligible apps were identified and downloaded into the iPad tablet computers, and then categorized according to the apps' initial contents and our using experiences. Methods about how to use the iPad's built-in functions of instant video call(FaceTime®and automatic data storage technology(iCloud®were also described together with the apps. Other operating systems of Microsoft's Window Phone and Google's Android were also searched for ophthalmology-relevant apps.RESULTS: The keywords for searching on the Apple's App Store were “ophthalmology” and “eye”. And we could found 111 eligible apps with the former keyword, and 452 ones with the latter one. The integrated uses of the iPad tablet computer were then categorized into five aspects. Based on our clinical practice, we finally summarized the advantages and disadvantages of the iPad tablet computer for ophthalmic practices. However, ophthalmology-relevant apps were found to be very limited in number on the other two platforms.CONCLUSION: The integrated use of self built-in apps and third-party apps can facilitate our clinical work in examination, telemedicine, reference, disease education and literature searching. More studies are needed to verify its validation and reliability in the professional fields, especially eye examinations.

  19. The foundation of experimental ophthalmology by Theodor Leber.

    Science.gov (United States)

    Jaeger, W

    1988-01-01

    Theodor Leber grew up in Heidelberg as the son of a professor of Romance languages. Initially he planned to study natural sciences. Bunsen's advice led him to medicine. During his studies he succeeded in solving a competition problem posed by Helmholtz in the medical department. A short period of practical work in the eye hospital of Knapp was unsatisfactory. In Vienna with the physiologist Carl Ludwig, he was able in 1863/64, at the age of only 24 years, to demonstrate the blood circulation of the eye by color injections into the arteries and veins. Since that time the schematic drawings of his results can be found in every textbook of ophthalmology. On the occasion of the congress of the German Ophthalmological Society in Heidelberg in 1864, Theodor Leber reported on these findings and met with immense approval. In 1864-67 he followed an invitation as coworker of Liebreich to Paris; in 1867 he became A.v. Graefe's coworker in Berlin; in 1871 he moved to Göttingen, which became the first eye clinic with a laboratory for experimental investigations. The second epoch-making discovery accomplished by Leber was the detection of the fluid exchange in the eye. These results have also been confirmed by modern methods. Therefore, Theodor Leber can be called the father of experimental ophthalmology.

  20. The human resource crisis in neuro-ophthalmology.

    Science.gov (United States)

    Frohman, Larry P

    2008-09-01

    Neuro-ophthalmology is facing a serious human resource issue. Few are entering the subspecialty, which is perceived as being poorly compensated compared with other subspecialties of ophthalmology. The low compensation comes from the fact that 1) non-procedural encounters remain undervalued, 2) efforts that benefit other medical specialists are not counted, and 3) the relatively low expenses of neuro-ophthalmologists are not factored into compensation formulas. Mission-based budgeting, which forces academic departments to be financially accountable without the expectation of fiscal relief from medical schools or practice plans, has exacerbated the compensation issue. Solutions must come from within neuro-ophthalmology, academic departments, medical schools, and medical practice plans. They include 1) providing educational resources so that neuro-ophthalmologists need not spend so much time teaching the basics, 2) factoring into compensation the impact of neuro-ophthalmologists in teaching and on revenue generation by procedure-based specialists, 3) improving the efficiency of neuro-ophthalmologists in their consultative practices by providing ample clerical support and other measures, 4) providing contractual salary compensation by departments such as neurosurgery to recognize the contributions made by neuro-ophthalmologists, and 5) reorganizing the academic clinical effort as multidisciplinary rather than departmental.

  1. History of the Secretariats of the American Academy of Ophthalmology.

    Science.gov (United States)

    Truhlsen, S M

    1996-08-01

    The American Academy of Ophthalmology and Otolaryngology grew steadily during its 82-year existence, and since 1979, the American Academy of Ophthalmology has had an accelerated increase in membership and activity. In 1995, as the Academy approached its centennial, the AAO had more than 20,000 members and an annual budget of more than +26 million. Total registration for the 1994 Annual meeting was slightly more than 27,000, an all-time high. Instruction Courses numbered 450,300 scientific papers were presented, and 130 posters were displayed. The original postgraduate course in 1921 served as the predecessor to the more than 700 hours of instruction presented at the 1994 Annual Meeting. The original committee of four was the predecessor of what has become the Secretariats of the Academy. The popular Home Study Courses were the forerunners of the Academy's programs, formulated and supervised by the Education Secretaries. The Clinical Education Programs include the Basic and Clinical Science Courses, Focal Points, Continuing Ophthalmic Video Education, Manuels, Regional Update Courses, Special Focus/Skills Courses, Monographs, PROvision, slide scripts, and other programs produced for allied health personnel, medical students, and other physicians. The Secretaries originate, produce, and oversee all the important functions of the Academy. The individuals who have served the Academy as Secretaries through the years have been dedicated volunteers. Their contributions have been incalculable. In recent years, the various Secretaries have been ably assisted by Associate Secretaries, Advisory Committees, and Subcommittees, spreading the workload of each Secretary. Credit for the success of the Academy's endeavors, while under the guidance of the Secretaries, also must be given to the Academy's many committee chairs and committee members who have diligently worked to achieve their goals and objectives. In 1995, the Executive Vice President, the 11 Secretaries, and the Editor

  2. [To strength interdisciplinary for the development of neuro-ophthalmology in China].

    Science.gov (United States)

    Wang, Ning-li

    2010-12-01

    Neuro-ophthalmology is an interdisciplinary field. Promoting the development of neuro-ophthalmology in China by interdisciplinary is the current trend. With the rapid development of the related disciplines, we should grasp the research hotspots correctly and focus on the oriented research. The cutting-edge research results should be introduced and the innovative teams should be built up. It will be greatly beneficial for the development of the neuro-ophthalmology in China by boosting the combination of neuro-ophthalmology and the cross subjects.

  3. Applications of nanobiotechnology in ophthalmology--Part I.

    Science.gov (United States)

    Nguyen, Pho; Meyyappan, M; Yiu, Samuel C

    2010-01-01

    Much progress has been achieved in the field of nanotechnology and its applications in ophthalmology. It is evident that drug delivery, gene therapy, implantable devices and regenerative medicine are some of the key areas of active research. To the best of our knowledge, there is limited review work on this subject area in the current literature. To assist the interested clinicians and scientists, this bipartite commentary will focus the discussion on emerging researches in nano-ophthalmology and other enabling technologies that soon may be available in the clinician's armamentarium to maintain and restore eye sight. This installment will focus on recent discoveries in drug delivery, gene therapy, imaging and visual prostheses; the second installment will discuss the impact of nanotechnology on artificial environment, cell-nanostructure interaction, other enabling nano-ophthalmic technologies, and safety and biocompatibility of nanostructures. We will take this opportunity to introduce some exciting nano-ophthalmic applications under investigation in our laboratory. The accomplishments by the scientific community are tremendous and the future prospects are wide open.

  4. Finlay y la oftalmología Finlay and ophthalmology

    Directory of Open Access Journals (Sweden)

    Elsa Lisset Arredondo Torres

    2012-04-01

    Full Text Available Se realizó una revisión bibliográfica acerca de la personalidad y la obra del científico camagüeyano Carlos Juan Finlay Barré, para ampliar y profundizar los conocimientos de médicos generales y oftalmólogos. En síntesis, se describe la vida de quien realizó trascendentales contribuciones a la medicina universal. Como sus descubrimientos sobre la fiebre amarilla irradian un conocimiento científico tan elevado, es necesario escudriñar sus aportes a la oftalmología. Se destacan algunos de los aportes más relevantes y de forma precisa se hace referencia a varios estudios realizados por él, así como la descripción de su técnica para la cirugía de catarata.A bibliographical revision on Carlos Juan Finlay Barré’s life and work was carried out to widen and deepen knowledge on general medicine and ophthalmology. In short, the life of man who made significant contributions to universal medicine is herein described. As his discoveries about the yellow fever have provided prominent scientific knowledge, so it is necessary to examine his contributions to ophthalmology. Some of his more relevant contributions and studies are also pointed out, as well as the description of his technique for cataract surgery.

  5. Medicinal plants used for ophthalmological problems in Navarra (Spain).

    Science.gov (United States)

    Calvo, M Isabel; Cavero, Rita Yolanda

    2016-08-22

    Several plants have been found to have effective against number of ophthalmological problems in Navarra. Information was collected using semi-structured ethnobotanical interviews with 686 informants in 267 locations. In order to confirm the pharmacological application of the uses more cited by the informants, a literature review was conducted. A total of 57 pharmaceutical uses were reported, for 19 plants and 13 families, mainly represented by Asteraceae. The most frequently used parts were inflorescences, flowers, aerial parts, leaves and flowered aerial parts. The related affections fell into eleven categories: bloodshot eyes, watery eyes and wounds, improve vision, irrited eyelids, rheums and styes, tired eyes, conjunctivitis, eyewash, ocular problems in general. The most cited plants were: Chamaemelum nobile (L.) All., Santolina chamaecyparissus L. ssp. squarrosa (DC.) Nyman, Sambucus nigra L. ssp. nigra, Rosa agrestis Savi and Calendula officinalis L. None of them have been pharmacologically validated by Official International Organisms. From the therapeutic point of view, Allium sativum L., Foeniculum vulgare Mill., C. officinalis, and S. chamaecyparissus ssp. squarrosa deserve special attention, because ethnobotanical and pharmacological studies suggest that these medicinal plants are effective for ophthalmological problems. The present study constitutes a good basis for further phytochemical and pharmacological research of these four plants, which could be of interest in the design of new inexpensive, effective and safe drugs. The remaining plants are needed to be screened through standard pharmacological and clinical procedures for their activities. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  6. The gamma knife in ophthalmology. Part One--Uveal melanoma.

    Science.gov (United States)

    Wygledowska-Promieńska, Dorota; Jurys, Małgorzata; Wilczyński, Tomasz; Drzyzga, Łukasz

    2014-01-01

    The Gamma Knife was designed by Lars Leksell in the early 1950's. It gave rise to a new discipline of medicine--stereotactic radiosurgery. Primarily dedicated to neurosurgery, the Gamma Knife has become an alternative, widely used surgery technique. According to Elekta's statistics, approximately 60,000 people are treated with Leksell Gamma Knife every year and it is the most extensively studied stereotactic radiosurgery system in the world. The Leksell Gamma Knife can also be used in ophthalmology. The gamma ray beam concentration enables effective treatment of uveal melanoma, choroidal hemangioma, orbital tumors or even choroidal neovascularization. The virtue of Leksell Gamma Knife is its extreme precision, non-invasiveness and the possibility of outpatient treatment, which significantly reduces costs and diminishes post-operative complications. Innovative solutions shorten a single session to a minimum, which is very comfortable and safe for both staff and patients. Advantages and possible side effects of gamma knife radiosurgery are well-documented in the professional literature. The objective of this review is to present the recognized applications of Leksell Gamma Knife in ophthalmology.

  7. Structured curricula and curriculum development in ophthalmology residency.

    Science.gov (United States)

    Lee, Andrew G; Chen, Ying

    2014-01-01

    There has been a shift in graduate medical education (GME) from the traditional "apprenticeship" model to a more curriculum-based and competency driven model. Reflecting a global trend towards residency education reform, the International Council of Ophthalmology (ICO) introduced a resident and specialist curriculum and several live educational programs to promote standardization and more effective GME and continuing professional training. Implementation of these educational innovations will require efforts by local educator champions; modification and customization of teaching and assessing tools to the local learning environment; alignment of the implementation blueprint with available resources; and creation of accountability and sustainability mechanisms to insure long-term viability of the educational reforms. An ultimate goal of the ICO curriculum is to allow real world testing and modification so that the ideas generated in one part of the world might be applicable and generalizable in other areas. We aim to describe the Accreditation Council of Graduate Medical Education (ACGME) competencies in the United States (US) and ICO curriculum, as well as to provide a step-by-step plan for implementation of an ophthalmology residency curriculum.

  8. [Training at the African Institute of Tropical Ophthalmology in Bamako].

    Science.gov (United States)

    Auzemery, A; Huguet, P; Audugé, A; Traoré, J; Ceccon, J F; Schémann, J F

    1998-01-01

    The African Institute of Tropical Ophthalmology (AITO) is an OCCCMED institute, founded in Bamako in 1953. The OCCCMED itself is based at Bobo Dioulasso (Burkina Faso). AITO is a WHO collaborating center for the prevention of blindness. Training is one of the main activities of the institute, along with eye care, research and assessment. The prevalence of blindness in sub-Saharan countries is about 1.2%, with blindness mostly caused by cataracts, trachoma, glaucoma and onchocercosis. The demand for eye care is high but there are currently too few trained personnel to satisfy that demand. Therefore, AITO's role in training eye-care professionals is particularly important. The institute trains ophthalmologists, specialist nurses, eye surgeons (who remove cataracts) and spectacle manufacturers. Training is carried out within the framework of the community and apprenticeship in the workplace. The student must attain specific targets, listed in a "competency passport" issued at the start of training. Clinical and surgical ophthalmology and general eye care are taught. Training costs and grants are mostly paid by the Lions Club International Sight First Program or by the French Overseas Development Ministry. Since 1991, AITO has trained to graduation: 18 ophthalmologists; 24 eye surgeons; 83 specialist nurses; 16 spectacle manufacturers.

  9. The Iowa ophthalmology wet laboratory curriculum for teaching and assessing cataract surgical competency

    NARCIS (Netherlands)

    Lee, Andrew G.; Greenlee, Emily; Oetting, Thomas A.; Beaver, Hilary A.; Johnson, A. Tim; Boldt, H. Culver; Abramoff, Michael; Olson, Richard; Carter, Keith

    2007-01-01

    Purpose To describe an ophthalmology wet laboratory (OWL) curriculum for residents in training. Methods Systematic literature review and selection of best practices for use in the OWL learning plan from a single academic ophthalmology program. Results A pretest and posttest of cognitive skills, ob

  10. LASER CORRELATION SPECTROSCOPY (LCS AND ITS CLINICAL PERSPECTIVES IN OPHTHALMOLOGY

    Directory of Open Access Journals (Sweden)

    Karganov Mikhail

    2015-12-01

    Full Text Available The method of laser correlation spectroscopy (LCS is based on the analysis of the spectrum of quasielastic light scatter during coherent monochromatic laser irradiation of micro-particles in biological fluids (blood serum, urine, oropharyngeal washout fluid, tear fluid etc.. Spectrum provides information on dynamic processes in the analyzed system: translation motion of scattering particles and their orientation and conformation dynamics. Special procedures of cluster analysis make it possible to find out to which linkage group a particular spectrum belongs. LCS allows evaluation of sub-fractional composition of biological fluids in a wide range of molecular sizes (from 1 to 10,000 nm, which determines principal novelty of this approach in ophthalmology.

  11. [Ophthalmologic manifestations in early and late stages of AIDS].

    Science.gov (United States)

    Schnaudigel, O E; Gümbel, H; Richter, R; Subklew, R; Garweg, T

    1994-10-01

    In a prospective study of 101 patients with HIV infection and a medium CD4 lymphocyte cell count of 350 x 10(6)/l and a retrospective study of the records of 79 AIDS patients, we compared the first ocular symptoms in HIV-infected patients to the CD4 count. In Walter-Reed stages 2-4 (n = 101) we found sicca syndrome in 9.2%, in 52% lens opacities in the cortex and only in less than 1% HIV-related angiopathy of the retina. In Walter Reed stages 5-6 (n = 79), 26% of the AIDS patients developed CMV retinitis, 33% HIV angiopathy of the retina and only 1% retinal toxoplasmosis. The average CD4 lymphocyte cell count was never better than 100 x 10(6). Lens opacities in HIV-infected patients could be an early ophthalmological symptom of HIV infection.

  12. Mitomycin-C and 5- FU in ophthalmology: review article

    Directory of Open Access Journals (Sweden)

    M Jabbarvand Behrouz

    2009-03-01

    Full Text Available "nThe response of living tissues to the surgical trauma is associated with varying degrees of tissue repair and involves two distinct processes including replacement and regeneration. Replacement results in scar tissue formation instead of restoration of the normal architecture. However, regeneration leads to restoration of the original architecture leaving no sign of injury. Anti-proliferative agents are used to inhibit tissue responses to surgical trauma. Among them mitomycin- C and 5- FU had gained increasing applications in ophthalmic surgeries, including filtering glaucoma surgeries, laser vision correction with excimer laser by ablative surface refractive surgery, reconstructive surgeries for ocular surface disorders and removal of neoplastic tissues and secondary operations on nasolacrimal ducts. In this review article, the various aspects of applications of these agents including their mechanism of action, function, mode of application and complications in different ophthalmology fields are discussed.

  13. [Gene therapy for hereditary ophthalmological diseases: Advances and future perspectives].

    Science.gov (United States)

    Chacón-Camacho, Óscar Francisco; Astorga-Carballo, Aline; Zenteno, Juan Carlos

    2015-01-01

    Gene therapy is a promising new therapeutic strategy that could provide a novel and more effective way of targeting hereditary ophthalmological diseases. The eye is easily accessible, highly compartmentalized, and an immune-privileged organ that gives advantages as an ideal gene therapy target. Recently, important advances in the availability of various intraocular vector delivery routes and viral vectors that are able to efficiently transduce specific ocular cell types have been described. Gene therapy has advanced in some retinal inherited dystrophies; in this way, preliminary success is now being reported for the treatment of Leber congenital amaurosis (LCA). This review will provide an update in the field of gene therapy for the treatment of ocular inherited diseases.

  14. Amniotic membrane allografts: development and clinical utility in ophthalmology

    Directory of Open Access Journals (Sweden)

    Rizzuti A

    2014-12-01

    Full Text Available Allison Rizzuti,1,2 Adam Goldenberg,1 Douglas R Lazzaro1,2 1SUNY Downstate Medical Center, 2Kings County Hospital Center, Brooklyn, NY, USA Abstract: Amniotic membrane, the innermost layer of the placenta, is a tissue that promotes epithelialization, while decreasing inflammation, neovascularization, and scarring. It is used in the surgical management of a wide variety of ophthalmic conditions where it functions as a graft or patch in ocular surface reconstruction. The development of new preservation techniques, as well as a sutureless amniotic membrane, has allowed for easier, in-office placement, without the disadvantages of an operating room procedure. The purpose of this review is to describe the historical development of amniotic membrane in ophthalmology and to describe its current clinical applications, particularly focusing on recent advances. Keywords: ocular surface, cornea, stem cells, prokera, allograft, patch, transplantation

  15. Neuro-ophthalmology and neuro-otology update.

    Science.gov (United States)

    Gold, Daniel R; Zee, David S

    2015-12-01

    This review summarizes topical papers from the fields of neuro-ophthalmology and neuro-otology published from August 2013 to February 2015. The main findings are: (1) diagnostic criteria for pseudotumor cerebri have been updated, and the Idiopathic Intracranial Hypertension Treatment Trial evaluated the efficacy of acetazolamide in patients with mild vision loss, (2) categorization of vestibular disorders through history and ocular motor examination is particularly important in the acute vestibular syndrome, where timely distinction between a central or peripheral localization is essential, (3) the newly described "sagging eye syndrome" provides a mechanical explanation for an isolated esodeviation that increases at distance in the aging population and (4) eye movement recordings better define how cerebellar dysfunction and/or sixth nerve palsy may play a role in other patients with esodeviations that increase at distance.

  16. Ophthalmology on social networking sites: an observational study of Facebook, Twitter, and LinkedIn

    Directory of Open Access Journals (Sweden)

    Micieli JA

    2015-02-01

    Full Text Available Jonathan A Micieli,1 Edmund Tsui2 1Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada; 2Department of Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA Background: The use of social media in ophthalmology remains largely unknown. Our aim was to evaluate the extent and involvement of ophthalmology journals, professional associations, trade publications, and patient advocacy and fundraising groups on social networking sites. Methods: An archived list of 107 ophthalmology journals from SCImago, trade publications, professional ophthalmology associations, and patient advocacy organizations were searched for their presence on Facebook, Twitter, and LinkedIn. Activity and popularity of each account was quantified by using the number of “likes” on Facebook, the number of followers on Twitter, and members on LinkedIn. Results: Of the 107 journals ranked by SCImago, 21.5% were present on Facebook and 18.7% were present on Twitter. Journal of Community Eye Health was the most popular on Facebook and JAMA Ophthalmology was most popular on Twitter. Among the 133 members of the International Council of Ophthalmology, 17.3% were present on Facebook, 12.8% were present on Twitter, and 7.5% were present on LinkedIn. The most popular on Facebook was the International Council of Ophthalmology, and the American Academy of Ophthalmology was most popular on Twitter and LinkedIn. Patient advocacy organizations were more popular on all sites compared with journals, professional association, and trade publications. Among the top ten most popular pages in each category, patient advocacy groups were most active followed by trade publications, professional associations, and journals. Conclusion: Patient advocacy groups lead the way in social networking followed by professional organizations and journals. Although some journals use social media, most have yet to engage its full potential and maximize the number of

  17. Intraoperative Flap Complications in LASIK Surgery Performed by Ophthalmology Residents

    Science.gov (United States)

    Romero-Diaz-de-Leon, Lorena; Serna-Ojeda, Juan Carlos; Navas, Alejandro; Graue-Hernández, Enrique O.; Ramirez-Miranda, Arturo

    2016-01-01

    Purpose: To report the rate of flap-related complications in LASIK surgery performed by in-training ophthalmology residents and to analyze the risk factors for these complications. Methods: We analyzed 273 flap dissections in 145 patients from March 2013 to February 2014. We included all LASIK surgeries performed by 32 ophthalmology residents using a Moria M2 microkeratome. All the flap-related complications were noted. Comparison between both groups with and without complications was performed with an independent Student's t-test and relative risks were calculated. Results: There were 19 flap-related complications out of the 273 flap dissections (6.95%). The most common complication was incomplete flap dissection (n = 10; 3.66%), followed by free-cap (n = 5; 1.83%), and flap-buttonhole (n = 2; 0.73%). There was no significant difference between the complicated and uncomplicated cases in terms of the right versus the left eye, pachymetry results, white-to-white diameter, and spherical equivalent. But this difference was significant for mean keratometry (P = 0.008), K-min (P = 0.01), and K-max (P = 0.03) between these groups. Final visual acuity after rescheduling laser treatment was similar in both groups. Relative risks for flap-related complications were 2.03 for the first LASIK surgery (CI 95% 0.64 to 6.48; P = 0.22) and 1.26 (CI 95% 0.43 to 3.69; P = 0.66) for the surgeon's flap-related complications. Female gender presented an odds ratio of 2.48 (CI 95% 0.68 to 9.00; P = 0.16) for complications. Conclusion: Flap-related complications are common intraoperative event during LASIK surgery performed by in-training ophthalmologists. Keratometries and surgeon's first procedure represent a higher probability for flap related complications than some other biometric parameters of patient's eye. PMID:27621782

  18. [Application of atomic force microscopy (AFM) in ophthalmology].

    Science.gov (United States)

    Milka, Michał; Mróz, Iwona; Jastrzebska, Maria; Wrzalik, Roman; Dobrowolski, Dariusz; Roszkowska, Anna M; Moćko, Lucyna; Wylegała, Edward

    2012-01-01

    Atomic force microscopy (AFM) allows to examine surface of different biological objects in the nearly physiological conditions at the nanoscale. The purpose of this work is to present the history of introduction and the potential applications of the AFM in ophthalmology research and clinical practice. In 1986 Binnig built the AFM as a next generation of the scanning tunnelling microscope (STM). The functional principle of AFM is based on the measurement of the forces between atoms on the sample surface and the probe. As a result, the three-dimensional image of the surface with the resolution on the order of nanometres can be obtained. Yamamoto used as the first the AFM on a wide scale in ophthalmology. The first investigations used the AFM method to study structure of collagen fibres of the cornea and of the sclera. Our research involves the analysis of artificial intraocular lenses (IOLs). According to earlier investigations, e.g. Lombardo et al., the AFM was used to study only native IOLs. Contrary to the earlier investigations, we focused our measurements on lenses explanted from human eyes. The surface of such lenses is exposed to the influence of the intraocular aqueous environment, and to the related impacts of biochemical processes. We hereby present the preliminary results of our work in the form of AFM images depicting IOL surface at the nanoscale. The images allowed us to observe early stages of the dye deposit formation as well as local calcinosis. We believe that AFM is a very promising tool for studying the structure of IOL surface and that further observations will make it possible to explain the pathomechanism of artificial intraocular lens opacity formation.

  19. Ophthalmological findings in series of incontinentia pigmenti patients from Serbia

    Directory of Open Access Journals (Sweden)

    Minić Snežana

    2010-01-01

    Full Text Available Introduction. Incontinentia pigmenti (IP is a rare complex X-linked genodermatosis in which skin changes are combined with anomalies of other organs. Mutations of the NEMO gene localized on chromosome Xq28 are responsible for IP. Clinical manifestations of IP according to evolution and prognosis can be considered as skin changes and dental, eye and central nervous system changes. Objective. The aim of our study was to investigate type and frequency of ocular features in Serbian population. Methods. We investigated the total of 9 families with 22 subjects, 20 females and 2 males, at the Institute of Dermatovenerology, Clinical Centre of Serbia, in the period from 1989 to 2009. Our subjects were diagnosed clinically by a dermatologist and the diagnosis confirmed by cutaneous histopathology and ultrastructural analysis. The pedigrees, karyotype analyses, routine laboratory findings, additional specialized clinical examinations were done for all subjects. Results. Among 22 IP patients from our study, different ophthalmological anomalies were observed in 16% of subjects. In female subjects, all of them with clinical characteristics of IP, we observed the following anomalies: retinal detachment, microphthalmia, cataract, strabismus and nystagmus. Conclusion. Compared to available literature data, our percentage of IP patients with anomalies was lower. It may be due to differences in examined populations or due to the fact that the patients in our study were firstly admitted to the Institute of Dermatology. Ophthalmological findings may be often considered as very severe anomalies in IP. It is very important to detect IP as early as possible, medically help and monitor these patients.

  20. Neuro-ophthalmologic manifestations of systemic lupus erythematosus: a systematic review.

    Science.gov (United States)

    Man, Bik Ling; Mok, Chi Chiu; Fu, Yat Pang

    2014-06-01

    Herein we summarize the clinical presentation, treatment and outcome of neuro-ophthalmologic manifestations in patients with systemic lupus erythematosus (SLE). We performed a systematic review of the neuro-ophthalmologic manifestations of SLE reported in the English literature from 1970 to 2010 by a Medline search. The prevalence of neuro-ophthalmologic manifestations is 3.6% in adult and 1.6% in childhood SLE patients. Neuro-ophthalmologic manifestations of SLE are highly variable, with the commonest presentation being optic neuritis, followed by myasthenia gravis, visual field defects and pseudotumor cerebri. The underlying pathology was thought to be either SLE activity or its vascular complications. Most neuro-ophthalmologic manifestations of SLE are responsive to high-dose glucocorticoids. Anticoagulation is indicated when there is concomitant antiphospholipid syndrome. SLE-related neuromyelitis optica is often refractory to treatment and 92% of patients require multiple immunosuppressive protocols. Neuro-ophthalmologic manifestations of SLE are uncommon but heterogeneous. The prognosis of neuro-ophthalmologic manifestations in SLE is generally good because of their rapid response to glucocorticoids. Relapses of these manifestations may be reduced by the use of maintenance immunosuppression. Cyclophosphamide, azathioprine, plasmapheresis, intravenous immunoglobulin and rituximab can be considered in glucocorticoid-dependent or refractory cases. Anticoagulation is indicated when there is concomitant antiphospholipid syndrome.

  1. Neuro-Ophthalmological Manifestations after Intramuscular Medroxyprogesterone: A Forme Fruste of Idiopathic Intracranial Hypertension?

    Science.gov (United States)

    Bahall, Mandreker; Reyes, Antonio Jose; Ramcharan, Kanterpersad; Hosein, Nadeem; Seegobin, Karan; Bahall, Krishni; Sharma, Hiranyadeva; Dhansingh, Stephanie; Mahabir, Amanda

    2016-09-30

    We report a case of a 22-year-old female student nurse who presented to hospital with an acute neuro-ophthalmological syndrome characterized by papilledema, ataxia, ophthalmoplegia and headache after a single first time use of 150 mg medroxyprogesterone intramuscular injection. Clinical, laboratory, radiological and ophthalmological investigations were in keeping with the diagnosis of idiopathic intracranial hypertension but lumbar puncture did not show a raised cerebrospinal fluid pressure suggesting a forme fruste of this entity. Her neuro-ophthalmological clinical features responded well to acetazolamide and diagnostic/therapeutic lumbar puncture. Full recovery was achieved three months after medroxyprogesterone usage. Health care providers must be aware of this adverse drug reaction.

  2. MR detection of retinal hemorrhages: correlation with graded ophthalmologic exam

    Energy Technology Data Exchange (ETDEWEB)

    Beavers, Angela J.; Allbery, Sandra M. [University of Nebraska Medical Center, Department of Radiology, Omaha, NE (United States); Children' s Hospital and Medical Center, Department of Radiology, Omaha, NE (United States); Stagner, Anna M.; Hejkal, Thomas W. [University of Nebraska Medical Center, Department of Ophthalmology, Omaha, NE (United States); Children' s Hospital and Medical Center, Department of Ophthalmology, Omaha, NE (United States); Lyden, Elizabeth R. [University of Nebraska Medical Center, College of Public Health, Omaha, NE (United States); Haney, Suzanne B. [Children' s Hospital and Medical Center, Department of Pediatrics, Omaha, NE (United States); University of Nebraska Medical Center, Department of Pediatrics, Omaha, NE (United States)

    2015-08-15

    Dilated fundoscopic exam is considered the gold standard for detecting retinal hemorrhage, but expertise in obtaining this exam is not always immediately available. MRI can detect retinal hemorrhages, but correlation of the grade or severity of retinal hemorrhage on dilated fundoscopic exam with retinal hemorrhage visibility on MRI has not been described. To determine the value of standard brain protocol MRI in detecting retinal hemorrhage and to determine whether there is any correlation with MR detection of retinal hemorrhage and the dilated fundoscopic exam grade of hemorrhage. We conducted a retrospective chart review of 77 children <2 years old who were seen for head trauma from April 2007 to July 2013 and had both brain MRI and dilated fundoscopic exam or retinal camera images. A staff pediatric radiologist and radiology resident reviewed the MR images. Retinal hemorrhages were graded by a chief ophthalmology resident on a 12-point scale based on the retinal hemorrhage type, size, location and extent as seen on review of retinal camera images and detailed reports by ophthalmologists. Higher scores indicated increased severity of retinal hemorrhages. There was a statistically significant difference in the median grade of retinal hemorrhage examination between children who had retinal hemorrhage detected on MRI and children who did not have retinal hemorrhage detected on MRI (P = 0.02). When examination grade was categorized as low-grade (1-4), moderate-grade (5-8) or high-grade (>8) hemorrhage, there was a statistically significant association between exam grade and diagnosis based on MRI (P = 0.008). For example, only 14% of children with low-grade retinal hemorrhages were identified on MRI compared to 76% of children with high-grade hemorrhages. MR detection of retinal hemorrhage demonstrated a sensitivity of 61%, specificity of 100%, positive predictive value of 100% and negative predictive value of 63%. Retinal hemorrhage was best seen on the gradient

  3. Myotonic dystrophy type 1: frequency of ophthalmologic findings

    Directory of Open Access Journals (Sweden)

    Karin Suzete Ikeda

    2016-03-01

    Full Text Available ABSTRACT The purpose of the study was to evaluate the frequency of ophthalmologic abnormalities in a cohort of myotonic dystrophy type 1 (DM1 patients and to correlate them with motor function. We reviewed the pathophysiology of cataract and low intraocular pressure (IOP. Method Patients were included after clinical and laboratory diagnosis and after signed informed consent. They were evaluated by Motor Function Measure scale, Portuguese version (MFM-P and ophthalmic protocol. Results We evaluated 42 patients aged 17 to 64 years (mean 40.7 ± 12.5, 22 of which were men. IOP (n = 41 was reduced in all but one. We found cataract or positivity for surgery in 38 (90.48% and ptosis in 23 (54.76%. These signs but not IOP were significantly correlated with severity of motor dysfunction. Abnormalities in ocular motility and stereopsis were observed. Conclusion Cataract and ptosis are frequent in DM1 and associated to motor dysfunction. Reduced IOP is also common, but appears not to be related with motor impairment.

  4. APOC impact assessment studies: baseline ophthalmological findings in Morogoro, Tanzania.

    Science.gov (United States)

    Babalola, O E; Maegga, B; Katenga, S; Ogbuagu, F K; Umeh, R E; Seketeli, E; Braide, E

    2008-12-01

    The goal of the African Programme for Onchocerciasis Control (APOC) is to eliminate Onchocerciasis as a disease of public Health significance and an important constraint to socio-economic development in the 19 none OCP (Onchocerciasis Control Project) countries covered through Community-Directed Treatment with Ivermectin, CDTI. In 1998, impact assessment studies were carried out in Morogoro, Tanzania during which baseline ophthalmological parameters were established. The hypothesis being tested is that CDTI will prevent or delay progression of onchocercal eye lesions and blindness. A total of 425 subjects aged 10 years or more from 14 villages within Bwakira district ofMorogoro region in Tanzania were examined for Snellen visual acuity, ocular microfilaria, lens opacities, uveitis and posterior segment disease especially chorioretinitis and optic nerve disease. Motion Sensitivity Screening Test (MSST) was carried out as well. Microfilaria was present in the anterior chamber of nearly half (49.2%) of all subjects examined. Prevalence of blindness was extremely high at 15.2%. Onchocercal lesions were responsible for blindness in 41.5% of these, followed by cataracts (27.7%), glaucoma (10.8%) and trachoma (6.2%). The main pathway to onchocercal blindness in this population was anterior uveitis with or without secondary cataracts. There is an urgent need to get CDTI underway and institute other horizontal primary eye care measures, especially cataract backlog reduction, in order to reduce the excessive burden of avoidable blindness in this community.

  5. A secure and synthesis tele-ophthalmology system.

    Science.gov (United States)

    Wei, Zhuo; Wu, Yongdong; Deng, Robert H; Yu, Shengsheng; Yao, Haixia; Zhao, Zhigang; Ngoh, Lek Heng; Han, Lim Tock; Poh, Eugenie W T

    2008-10-01

    This paper describes a secure and synthesis ophthalmology telemedicine system, referred to as TeleOph. Under a Secure Socket Layer (SSL) channel, patient prerecorded data can be safely transferred via the Internet. With encrypted videoconference and white-board, the system not only supports hospital-to-clinic consultation, but also supplies hospital-tohospital joint discussion. Based on Directshow technology (Microsoft Corporation, Redmond, WA), video cameras connected to the computer by firewire can be captured and controlled to sample video data. By using TWAIN technology, the system automatically identifies networked still cameras (on fundus and slitlamp devices) and retrieves images. All the images are stored in a selected format (such as JPEG, DICOM, BMP). Besides offline-transferring prerecorded data, the system also supplies online sampling of patient data (real-time capturing from remote places). The system was deployed at Tan Tock Seng Hospital, Singapore and Ang Mo Kio, Singapore, where 100 patients were enrolled in the system for examination. TeleOph can be successfully used for patient consultation, and hospital joint discussion. Meanwhile, TeleOph can supply both offline and online sampling of patient data.

  6. Physician use of white coats in pediatric ophthalmology.

    Science.gov (United States)

    DeBenedictis, Caroline N; Liu, Grace T; Nelson, Leonard B; Leiby, Benjamin E; Dai, Yang; Levin, Alex V

    2014-01-01

    Recent literature reports that patients and parents of pediatric patients prefer their physician to wear a white coat and to address them informally. This study aims to characterize current practice patterns of pediatric ophthalmologists regarding their use of white coats and salutations during outpatient pediatric encounters. An eight-question survey was e-mailed to members of the American Academy of Pediatric Ophthalmology and Strabismus in 2012. The questions focused on clinical setting, use of white coats in out-patient encounters, and preferred language used to address the patient's parents. Surveys not completed in full were excluded from data analysis. Of approximately 1,266 members who received the survey, 606 completed the survey. Five hundred ninety-nine surveys were included in the data analysis. Sixty-three percent of attending physicians and 80% of fellows reported they did not routinely wear white coats while examining outpatient children. Forty-six percent of attending physicians and 48% of fellows addressed the patient's parents as "mom" or "dad". There was no significant association between wearing a white coat and type of practice setting, practice characteristics, or location in a children's hospital for attending physicians or fellows. Contrary to preferences expressed by patients and their parents, a majority of pediatric ophthalmologists do not routinely wear white coats during pediatric outpatient examinations. Practice patterns appear to be in line with previously reported parental greeting preferences. Copyright 2014, SLACK Incorporated.

  7. CHOROIDAL THICKNESS IN MULTISYSTEMIC AUTOIMMUNE DISEASES WITHOUT OPHTHALMOLOGIC MANIFESTATIONS.

    Science.gov (United States)

    Ferreira, Carla S; Beato, João; Falcão, Manuel S; Brandão, Elisete; Falcão-Reis, Fernando; Carneiro, Ângela M

    2017-03-01

    To evaluate choroidal morphology and thickness at the posterior pole of individuals affected by multisystemic autoimmune diseases and without known ophthalmologic manifestations. Retrospective cross-sectional study including 75 patients with autoimmune diseases (divided according to their specific disease) and 80 healthy controls. A spectral-domain optical coherence tomography using enhanced depth imaging was performed and choroidal thickness was measured in the center of fovea and at 500 μm intervals along a horizontal section. Lupus patients presented a thicker subfoveal choroid than controls (408.624 vs. 356.536, P choroid than controls (297.867 vs. 356.536 subfoveally, P = 0.004; P = 0.005-0.019 in other measurements). Results were adjusted for the covariates age (P = 0.007), spherical equivalent (P choroidal thickness. No morphologic abnormalities were found. The choroid may be subclinically involved in autoimmune diseases. However, the choroidal response seems to differ depending on the autoimmune disease. Infiltrative mechanisms specific for lupus may justify the thickened choroid found in these patients.

  8. [Genome Editing Tools and their Application in Experimental Ophthalmology].

    Science.gov (United States)

    Yanik, M; Wende, W; Stieger, K

    2017-01-23

    New genome editing tools in molecular biology are revolutionising precise genome surgery and have greatly influenced experimental ophthalmology too. Aside from the commonly used nuclease-based platforms, such as the zinc-finger nucleases (ZFN) and transcription activator-like effector nucleases (TALEN), CRISPR/Cas systems, clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) genes, perform very efficiently in site-specific DNA cleavage within living cells. DNA double strand breaks (DSB) are repaired through two different conserved repair pathways: NHEJ (non-homologous end joining) and HDR (homology directed repair). By using the correct DNA templates, these repair pathways can be used to knock out defective genes or to repair mutations. Genome editing technology lays the ground for new strategies in basic science, biotechnology, and biomedical science, as well as clinical studies with genome editing. Therapeutic gene editing strategies are now concentrating on diseases in the retina, due to the comparatively easy accessibility of the eye and with local application in vivo.

  9. Future trends in ophthalmology health human resources in Canada.

    Science.gov (United States)

    Bellan, Lorne

    2016-06-01

    Projections of future Canadian ratios of ophthalmologists to population have fluctuated because of changes in numbers of residency spots and retirement rates. Although this ratio plateaued in recent years, the ratio of ophthalmologists to the population over 65 years of age is projected to steadily deteriorate. All graduating residents are going to be needed to meet the upcoming workload, yet current graduates are finding increasing difficulty obtaining full-time positions with operating room privileges. This problem is affecting all specialties who require hospital facilities, and exploration of this problem by the Royal College, Canadian Medical Association (CMA), Resident Doctors of Canada, and council of the Provincial Deputy Ministers of Health is presented. Proposed solutions to the current job shortages include residents starting in positions outside of major metropolitan areas, clinicians in practice giving up some operating room time to make way for new graduates, government increasing infrastructure commensurate with the increased number of medical school positions, and optimizing use of current resources by running operating rooms for longer hours and on the weekends. Copyright © 2016 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights reserved.

  10. Drug Utilization Study in Ophthalmology Out‑patient Department of a ...

    African Journals Online (AJOL)

    and escalation in the pricing of drugs have increased the importance of ... the drug utilization pattern in ophthalmology out‑patient department (OPD) of a Medical. College in India. .... Malaysia; the findings of a household survey. Al Ameen J.

  11. Ophthalmological abnormalities in children with congenital disorders of glycosylation type I.

    NARCIS (Netherlands)

    Morava, E.; Wosik, H.; Sykut-Cegielska, J.; Adamowicz, M.; Guillard, M.; Wevers, R.A.; Lefeber, D.J.; Cruysberg, J.R.M.

    2009-01-01

    BACKGROUND: Children with congenital disorders of glycosylation (CDG) type Ia frequently present with ocular involvement and visual loss. Little is known, however, about the occurrence of ophthalmological abnormalities in other subtypes of CDG syndrome. METHODS: We evaluated 45 children sequentially

  12. The History and Founding Organizations of the American Board of Ophthalmology.

    Science.gov (United States)

    Spivey, Bruce E

    2016-09-01

    In the early 1900s, ophthalmologists became the first group of American physicians to lead the call for the establishment of higher standards in the practice of medicine. This movement for excellence in practice evolved into a program of board certification through the creation of what is today the American Board of Ophthalmology (ABO). Three organizations-the American Ophthalmological Society, the Section on Ophthalmology of the American Medical Association, and the American Academy of Ophthalmology and Otolaryngology-are credited as the founders of the ABO. Representatives from these organizations were charged with overseeing the development of board certification programs from the ABO's inception in 1916 through 1982, when it became a fully autonomous organization.

  13. Enhancing best practices in ophthalmology for prevention of nosocomial epidemic keratoconjunctivitis infections.

    Science.gov (United States)

    Alai, Nili

    2016-10-01

    Epidemic keratoconjunctivitis (EKC) outbreaks were reported as early as the 1940s in the United States. Nearly 80 years later, EKC remains a major eye health concern in the US and worldwide. Of particular concern is that a significant number of EKC cluster outbreaks in the US are healthcare acquired infections (HAIs) at ophthalmology offices. Therefore, immediate attention to enhancing best practices of standardization and universal precautions in ophthalmology is paramount.

  14. [Ophthalmological manifestations of Cornelia de Lange syndrome: Case report and review of the literature].

    Science.gov (United States)

    Avgitidou, G; Cursiefen, C; Heindl, L M

    2015-05-01

    A 2-year-old boy suffering from Cornelia de Lange syndrome, presented with mucopurulent ocular discharge and epiphora since birth. Irrigation and probing of the nasolacrimal system revealed and successfully treated bilateral nasolacrimal duct obstructions. Cornelia de Lange syndrome is characterized not only by typical facial features, visceral and urogenital anomalies but also by ophthalmological manifestations in 99% of cases. The most common ophthalmological disorders are synophrys, blepharitis, epiphora, hypertrichosis of the eyebrows and eyelashes, myopia, ptosis and nasolacrimal duct obstruction.

  15. Ophthalmology on social networking sites: an observational study of Facebook, Twitter, and LinkedIn.

    Science.gov (United States)

    Micieli, Jonathan A; Tsui, Edmund

    2015-01-01

    The use of social media in ophthalmology remains largely unknown. Our aim was to evaluate the extent and involvement of ophthalmology journals, professional associations, trade publications, and patient advocacy and fundraising groups on social networking sites. An archived list of 107 ophthalmology journals from SCImago, trade publications, professional ophthalmology associations, and patient advocacy organizations were searched for their presence on Facebook, Twitter, and LinkedIn. Activity and popularity of each account was quantified by using the number of "likes" on Facebook, the number of followers on Twitter, and members on LinkedIn. Of the 107 journals ranked by SCImago, 21.5% were present on Facebook and 18.7% were present on Twitter. Journal of Community Eye Health was the most popular on Facebook and JAMA Ophthalmology was most popular on Twitter. Among the 133 members of the International Council of Ophthalmology, 17.3% were present on Facebook, 12.8% were present on Twitter, and 7.5% were present on LinkedIn. The most popular on Facebook was the International Council of Ophthalmology, and the American Academy of Ophthalmology was most popular on Twitter and LinkedIn. Patient advocacy organizations were more popular on all sites compared with journals, professional association, and trade publications. Among the top ten most popular pages in each category, patient advocacy groups were most active followed by trade publications, professional associations, and journals. Patient advocacy groups lead the way in social networking followed by professional organizations and journals. Although some journals use social media, most have yet to engage its full potential and maximize the number of potential interested individuals.

  16. [Ophthalmology in the ancient river cultures. Was cataract surgery performed during the time of King Hammurabi?].

    Science.gov (United States)

    Bieganowski, Lech

    2003-01-01

    The article presents the state of ophthalmological knowledge in the Ancient River Cultures. Medical and ophthalmological information included in King Hammurabi Code is discussed. The author presents a critical analysis of the views related to the hypothesis of possible performance of cataract operation in Babylon during the Hammurabi period. Terminological and medical matters related to this issue are discussed. The original opinion about surgical treatment of symblepharon or pannus trachomatosus is presented.

  17. Headache medicine meets neuro-ophthalmology: exam techniques and challenging cases.

    Science.gov (United States)

    Friedman, Deborah I; Digre, Kathleen B

    2013-04-01

    The neuro-ophthalmology examination is critical to anyone who sees patients with the common symptom of headache. By examining the visual acuity, pupils, visual fields, motility, and fundus, clues to both secondary causes of headache and primary headaches exist. In this review, we discuss how to do the neuro-ophthalmology examination and we review cases of primary and secondary headache where key features of the examination assisted in making the correct diagnosis.

  18. Raman-spectroscopy-based biosensing for applications in ophthalmology

    Science.gov (United States)

    Rusciano, Giulia; Capriglione, Paola; Pesce, Giuseppe; Zito, Gianluigi; Del Prete, Antonio; Cennamo, Giovanni; Sasso, Antonio

    2013-05-01

    Cell-based biosensors rely on the detection and identification of single cells as well as monitoring of changes induced by interaction with drugs and/or toxic agents. Raman spectroscopy is a powerful tool to reach this goal, being non-destructive analytical technique, allowing also measurements of samples in aqueous environment. In addition, micro-Raman measurements do not require preliminary sample preparation (as in fluorescence spectroscopy), show a finger-print spectral response, allow a spatial resolution below typical cell sizes, and are relatively fast (few s or even less). All these properties make micro-Raman technique particularly promising for high-throughput on-line analysis integrated in lab-on-a-chip devices. Herein, we demonstrate some applications of Raman analysis in ophthalmology. In particular, we demonstrate that Raman analysis can provide useful information for the therapeutic treatment of keratitis caused by Acanthamoeba Castellanii (A.), an opportunistic protozoan that is widely distributed in the environment and is known to produce blinding keratitis and fatal encephalitis. In particular, by combining Raman analysis with Principal Component Analysis (PCA), we have demonstrated that is possible to distinguish between live and dead cells, enabling, therefore to establish the effectiveness of therapeutic strategies to vanquish the protozoa. As final step, we have analyzed the presence of biochemical differences in the conjunctival epithelial tissues of patients affected by keratitis with respect to healthy people. As a matter of facts, it is possible to speculate some biochemical alterations of the epithelial tissues, rendering more favorable the binding of the protozoan. The epithelial cells were obtained by impression cytology from eyes of both healthy and keratitis-affected individuals. All the samples were analyzed by Raman spectroscopy within a few hours from cells removal from eyes. The results of this analysis are discussed.

  19. Neuro-ophthalmological approach to facial nerve palsy

    Science.gov (United States)

    Portelinha, Joana; Passarinho, Maria Picoto; Costa, João Marques

    2014-01-01

    Facial nerve palsy is associated with significant morbidity and can have different etiologies. The most common causes are Bell’s palsy, Ramsay–Hunt syndrome and trauma, including surgical trauma. Incidence varies between 17 and 35 cases per 100,000. Initial evaluation should include accurate clinical history, followed by a comprehensive investigation of the head and neck, including ophthalmological, otological, oral and neurological examination, to exclude secondary causes. Routine laboratory testing and diagnostic imaging is not indicated in patients with new-onset Bell’s palsy, but should be performed in patients with risk factors, atypical cases or in any case without resolution within 4 months. Many factors are involved in determining the appropriate treatment of these patients: the underlying cause, expected duration of nerve dysfunction, anatomical manifestations, severity of symptoms and objective clinical findings. Systemic steroids should be offered to patients with new-onset Bell’s palsy to increase the chance of facial nerve recovery and reduce synkinesis. Ophthalmologists play a pivotal role in the multidisciplinary team involved in the evaluation and rehabilitation of these patients. In the acute phase, the main priority should be to ensure adequate corneal protection. Treatment depends on the degree of nerve lesion and on the risk of the corneal damage based on the amount of lagophthalmos, the quality of Bell’s phenomenon, the presence or absence of corneal sensitivity and the degree of lid retraction. The main therapy is intensive lubrication. Other treatments include: taping the eyelid overnight, botulinum toxin injection, tarsorrhaphy, eyelid weight implants, scleral contact lenses and palpebral spring. Once the cornea is protected, longer term planning for eyelid and facial rehabilitation may take place. Spontaneous complete recovery of Bell’s palsy occurs in up to 70% of cases. Long-term complications include aberrant regeneration

  20. [Ophthalmological experiences with automobile drivers with inadequate vision].

    Science.gov (United States)

    Harms, H; Kröner, B; Dannheim, R

    1984-08-01

    A total of 369 ophthalmological practices were asked to report the number of patients seen within one test week who drove their cars but did not satisfy minimum legal requirements for diurnal visual acuity applicable for applicants for a West German Class 3 driver's license. There were 471 such patients. From this number it can be calculated that approximately 570 000 individuals (+/- 9%) drive cars in the Federal Republic of Germany with inadequate visual acuity. An analysis of the questionnaire produced the following results: Fifty percent of these patients are less than 62 years of age. The main cause of inadequate visual acuity is age. In younger drivers refractive errors were the prime cause and in most cases correction with glasses was possible. In older drivers the loss of acuity was mainly due to opacities of the lens which for the most part could not be corrected by spectacles. Two-thirds of the drivers with inadequate visual acuity consider their vision to be "sufficient" or "good" for driving; younger drivers are more self-critical than older ones. Only 31% of these drivers stopped driving at night of their own accord. As many as two-thirds of the drivers who consider their acuity to be "insufficient" drive their cars during darkness. The authors show that the findings in patients suffering from severe loss of visual acuity must in principle also be valid for patients with minor visual impairments who still meet the minimum legal requirements. This agrees well with published statistical investigations.(ABSTRACT TRUNCATED AT 250 WORDS)

  1. Representation of Women With Industry Ties in Ophthalmology.

    Science.gov (United States)

    Reddy, Ashvini K; Bounds, Gregory W; Bakri, Sophie J; Gordon, Lynn K; Smith, Justine R; Haller, Julia A; Thorne, Jennifer E

    2016-06-01

    Women in ophthalmology are growing in number and have made strides in traditional metrics of professional achievement. Professional ties to industry represent another potential means of career advancement, recognition, and income. To report the representation of women among ophthalmologists receiving industry remuneration for research, consulting, honoraria, grants, royalties, and faculty/speaker roles. In this observational, retrospective study, the Centers for Medicare and Medicaid Services Open Payments database for payments to ophthalmologists by biomedical companies was reviewed for representation, median payments, and mean payments by women and men for industry relationships in 2013 and 2014. The analysis was performed from July 2015 to November 2015. The primary outcome measures were percentage representation of women vs men overall and in industry research, consulting, speaking roles, royalties and licenses, grants, services other than consulting, and honoraria. Secondary outcome measures included mean and median payments from industry to female vs male ophthalmologists. In 2013, 4164 of 21 380 (19.5%) ophthalmologists were women, and of 1204 ophthalmologists analyzed for industry payments, 176 (4.2%) women had industry ties compared with 1028 (6%) men (P women were $11 419 compared with $20 957 for men (P = .001), and median payments to women were $3000 compared with $4787 for men (P = .007). In 2013, women were underrepresented among ophthalmologists receiving industry payments for research (49 of 462 [10.6%]), consulting (96 of 610 [15.7%]), honoraria (3 of 47 [6.4%]), industry grants (1 of 7 [14.3%]), royalties and licenses (1 of 13 [7.7%]), and faculty/speaker roles (2 of 48 [4.2%]). In 2014, 4352 of 21 531 (20.2%) of ophthalmologists were women. Of 1518 ophthalmologists analyzed for industry payments, 255 (6%) women had industry ties compared with 1263 (7.4%) men (P women were $14 848 compared with $30 513 for men (P = .004

  2. Publications and Presentations of the Ophthalmology Branch, U.S. Air Force School of Aerospace Medicine, 2006-2010

    Science.gov (United States)

    2013-12-01

    AFRL-SA-WP-SR-2013-0015 Publications and Presentations of the Ophthalmology Branch, U.S. Air Force School of Aerospace Medicine, 2006...Aerospace Medicine Aerospace Medicine Department Ophthalmology Branch 2510 Fifth St. Wright-Patterson AFB, OH 45433-7913 Distribution A: Approved... Ophthalmology Branch, U.S. Air Force School of Aerospace Medicine, 2006-2010 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER

  3. Relocation consequences on an ophthalmology consultation service from an inpatient to outpatient facility

    Directory of Open Access Journals (Sweden)

    Singh JS

    2015-10-01

    Full Text Available Jorawer S Singh,1 Vincent M Imbrogno,2 Mary K Howard,3 Amandip S Cheema,3 Ausra D Selvadurai,4 Surbhi Bansal5 1Department of Ophthalmology, George Washington University, Washington, DC, 2Contemporary Ophthalmology of Erie, Erie, PA, 3Department of Ophthalmology, University at Buffalo, Buffalo, NY, 4OcuSight Eye Care Center, Rochester, NY, 5Department of Ophthalmology, Virginia Commonwealth University, Richmond, VA, USA Importance: This study shows that relocation of an academic ophthalmology residency program from an inpatient to an outpatient setting in western New York does not affect the consult volume but affects management patterns and follow-up rates.Objective: To investigate the effects on the ophthalmology consultation service of an academic program with relocation from a Regional Level-1 Trauma center to an outpatient facility.Design: Consultation notes from 3 years before and 3 years after the University at Buffalo’s (UB Department of Ophthalmology relocation from a Regional Level-1 Trauma center (Erie County Medical Center to an outpatient facility (Ross Eye Institute were obtained from hospital electronic medical records and analyzed.Setting: Hospitalized care and institutional practice.Participants: All inpatient or Emergency Room Ophthalmology consultation patients from the Department of Ophthalmology at UB from 2004 to 2010 (1,379 patients.Exposures: None, this was a retrospective chart review.Main outcome measures: Patient demographics, reason for consult, diagnoses, and ophthalmic procedures performed by the UB Department of Ophthalmology before and after its relocation.Results: Relocation to the outpatient facility did not affect consult volume (P=0.15. The number of consults focusing on ophthalmic conditions, as a percentage of the yearly total, rose 460% (P=0.0001, while systemic condition consults with ocular manifestations fell 83% (P=0.0001. Consults for ocular trauma decreased 65% (P=0.0034. Consults ending with a

  4. The 101 most frequently cited articles in ophthalmology journals from 1850 to 1949.

    Science.gov (United States)

    Ohba, Norio; Nakao, Kumiko

    2010-12-01

    We screened 32 ophthalmology journals that had published articles during the period from 1850 through 1949 to identify top-cited articles in the field of ophthalmology (hereafter referred to as citation classics) using the online database Science Citation Index Expanded (Thompson Reuters, Chicago, Illinois). The 101 most frequently cited articles were published in 16 journals. Archives of Ophthalmology had the most top-cited articles (n = 31), followed by American Journal of Ophthalmology (n = 24) and Albrecht von Graefe's Archiv für Ophthalmologie (n = 9). These articles originated from 14 countries, with the United States publishing the majority (n = 58). Most of the citation classics are clinical studies on topics such as rubella cataract, retinopathy of prematurity, keratoconjunctivitis sicca, sympathetic ophthalmia, and the first report of eponymous diseases (eg, Leber hereditary optic neuropathy, Duane retraction syndrome, and Stargardt disease). A considerable number of these articles were ignored initially and for several decades after publication, but, like the classic fairy tale Sleeping Beauty, they have been rediscovered. Our study provides a historical perspective on the classic papers in the literature that are still influential in ophthalmology.

  5. Neuro-ophthalmological manifestations after intramuscular medroxyprogesterone: a forme fruste of idiopathic intracranial hypertension?

    Directory of Open Access Journals (Sweden)

    Mandreker Bahall

    2016-09-01

    Full Text Available We report a case of a 22-year-old female student nurse who presented to hospital with an acute neuro-ophthalmological syndrome characterized by papilledema, ataxia, ophthalmoplegia and headache after a single first time use of 150 mg medroxyprogesterone intramuscular injection. Clinical, laboratory, radiological and ophthalmological investigations were in keeping with the diagnosis of idiopathic intracranial hypertension but lumbar puncture did not show a raised cerebrospinal fluid pressure suggesting a forme fruste of this entity. Her neuro-ophthalmological clinical features responded well to acetazolamide and diagnostic/ therapeutic lumbar puncture. Full recovery was achieved three months after medroxyprogesterone usage. Health care providers must be aware of this adverse drug reaction.

  6. Association between burnout and anger in oncology versus ophthalmology health care professionals.

    Science.gov (United States)

    Muscatello, M R A; Bruno, A; Carroccio, C; Cedro, C; La Torre, D; Di Rosa, A E; Zoccali, R; Aragona, M; La Torre, F; Mattei, A; Angelone, A M; Di Orio, F

    2006-10-01

    The prevalence of burnout in oncology staff was compared with that of the ophthalmology staff, who normally present a low prevalence of burnout as described in this literature. The correlation of burnout with the emotion of anger was also investigated. Thirty-six subjects working in an oncology department and 32 working in an ophthalmology department were examined using the Maslach Burnout Inventory and the State-Trait Anger Expression Inventory. The oncology group showed higher mean scores on the MBI Emotive Exhaustion and Depersonalization scales with respect to ophthalmology staff. Correlation analysis showed that increasing burnout was associated with higher anger expressed towards the environment and loss of anger control. Anger, as a response to frustration, appears to be a feature constantly associated with the clinical expression of burnout and it should not be underestimated in theoretical and preventive contexts.

  7. Role of journal club in Canadian ophthalmology residency training: a national survey of program directors.

    Science.gov (United States)

    Mullen, Sarah J; Sabri, Kourosh

    2016-06-01

    To conduct a national survey of journal club curricula in Canadian ophthalmology residency programs. Cross-sectional web-based survey. Fifteen Royal College of Physicians and Surgeons of Canada (RCPSC) ophthalmology residency program directors. The 15 RCPSC ophthalmology residency program directors were invited to participate in a 31-item online survey. The survey inquired about the purpose, educational goals, and structure of journal club. Basic statistics were performed to compare responses across institutions. Thirteen of the 15 program directors replied, representing an 87% response rate. Twelve (92%) institutions maintained a journal club. All of the program directors surveyed felt that journal club had educational value. Resident attendance was typically mandatory (75%) and correspondingly high across programs. There was 100% agreement that randomized controlled trials were most often selected for review. The primary journal club objectives were for residents to develop critical appraisal skills and to conduct a literature search (67%). Formal teaching and evaluation of these skills were not prioritized by any program. Seventeen percent felt the most important objective was to impact clinical practice. Canadian ophthalmology program directors expressed high levels of satisfaction that journal club was effective in meeting its stated objectives. This indicates that the teaching model promoted resident critical appraisal skills; however, objective evaluation methods to assess resident competence in evidence-based medicine were not described by any respondents. As RCSPC ophthalmology programs transition to competency-based medical education, program directors may consider modifying journal club curriculum, broadening its utility toward a means of outcome assessment. Copyright © 2016 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights reserved.

  8. Effectiveness of a 40-minute Ophthalmologic Examination Teaching Session on Medical Student Learning

    Directory of Open Access Journals (Sweden)

    Wirachin Hoonpongsimanont

    2015-10-01

    Full Text Available Introduction: Emergency physicians are among the few specialists besides ophthalmologists who commonly perform ophthalmologic examinations using the slit lamp and other instruments. However, most medical schools in the United States do not require an ophthalmology rotation upon completion. Teaching procedural skills to medical students can be challenging due to limited resources and instructor availability. Our study assesses the effectiveness of a 40-minute hands-on teaching session on ophthalmologic examination for medical students using only two instructors and low-cost equipment. Methods: We performed an interventional study using a convenience sample of subjects. Pre- and post-workshop questionnaires on students’ confidence in performing ophthalmologic examination were administered. We used a paired t-test and Wilcoxon rank test to analyze the data. Results: Of the 30 participants in the study, the mean age was 25 and the majority were first-year medical students. The students’ confidence in performing every portion of the ophthalmologic exam increased significantly after the teaching session. We found that the average confidence level before the teaching session were below 2 on a 1-5 Likert scale (1 being the least confident. Confidence levels in using the slit lamp had the highest improvement among the skills taught (2.17 95% CI [1.84-2.49]. Students reported the least improvement in their confidence in assessing extraocular movements (0.73, 95% CI [0.30-1.71] and examining pupillary function (0.73, 95% CI [0.42-1.04]. We observed the biggest difference in median confidence level in the use of the tonometer (4 with a p-value of <0.05. Conclusion: A 40-minute structured hands-on training session can significantly improve students’ confidence levels in ophthalmologic skills.

  9. [Modern ultrasound methods of examination in clinical ophthalmology. Background problems and future prospects].

    Science.gov (United States)

    Kharlap, S I

    2003-01-01

    Historic aspects of ultrasound diagnostics in ophthalmology are described. The technological development of ultrasound diagnostic systems and the clinical application of different ultrasound modes in examining the eye and its choroids are traced back. The efficiency of Doppler mapping in the mode of three-dimension reconstruction at examining the orbital vascular system is evaluated. An experience obtained at the Research Institute for Eye Disease of the Russian Academy of Medical Sciences and outlooks for the diagnostic usage of computer ultrasound in clinical ophthalmology and angiologia are presented.

  10. [Pay attention to application of pupil reaction testing in assessment of neuro-ophthalmologic disorders].

    Science.gov (United States)

    Zhong, Yong

    2009-12-01

    The pupillary light reaction represents the functions of either the afferent visual pathway or the pupillary efferent innervations (parasympathetic and sympathetic). Physiologic and pathologic changes of pupil were usually ignored by the physicians. A correct pupil reaction testing will be of benefit to catch the abnormal pupil reaction as well as the early diagnosis of neuro-ophthalmologic disorders. A precise pupil reaction test is hardly performed because of the variation of individual, illumination and the instantaneous change of pupil. The proper pharmacologic testing is helpful for choosing the right neuro-electrophysiological and neuro-image examinations, and also may be of instruction value on the diagnosis of neuro-ophthalmologic diseases.

  11. Neuro-ophthalmological emergencies: which ocular signs or symptoms for which diseases?

    Science.gov (United States)

    Cordonnier, Monique; Van Nechel, Christian

    2013-09-01

    There are five possible ocular signs or complaints of a life or sight threatening neuro-ophthalmological condition: diplopia, isolated anisocoria, transient visual loss, severe pain in head or neck (with or without photophobia) and oscillopsia/nystagmus. In this review, the ocular signs and symptoms of neuro-ophthalmological emergencies are described together with their practical work-up and the risks associated with missing the diagnosis. Concerning diplopia, the associated signs pointing to a possible threatening condition are emphasized. Six focus points resuming core messages are displayed throughout this review.

  12. Ophthalmologic complications after intraoral local anesthesia: case report and review of literature

    NARCIS (Netherlands)

    Steenen, S.A.; Dubois, L.; Saeed, P.; de Lange, J.

    2012-01-01

    Intraoral administration of local anesthetics is one of the most common dental procedures. Ophthalmologic complications can occur after maxillary as well as mandibular local anesthetic injections and may be underreported and sometimes misinterpreted. A review of the literature from the years

  13. [Surgeon and eye doctor Caspar Stromayr and the ophthalmological illustrations in his "Practica copiosa" (1559)].

    Science.gov (United States)

    Nover, A; Kümmel, W F

    1984-11-01

    In 1559 Caspar Stromayr wrote a richly illustrated book about hernias and their treatment. The manuscript also includes 3 chapters of a book on ophthalmological diseases which, however, was never published. In addition, it contains 6 separate watercolor illustrations of eye diseases, though without any explanatory texts. The authors attempt to interpret these first colored pictures of eye diseases.

  14. Medico-sociological analysis of consulting work at ophthalmologic regional hospital: communication approach

    Directory of Open Access Journals (Sweden)

    lorina I.G.

    2012-09-01

    Full Text Available The purpose of the article is to considerthe consulting work as a process of social communication. The way of such approach allowed to determine objective and function of communication system of ophthalmologic regional hospital, to consider the problems of communication management concerning the problem of computerization of Russian Health Service.

  15. [Suggestion of an improved technique of general anaesthesia for ophthalmological experiments on rabbits (author's transl)].

    Science.gov (United States)

    Holtmann, H W; Stein, H J

    1975-02-01

    The potentiated general anaesthesia with ethyl urethane and propionylpromazine for long-time ophthalmological experiments on rabbits is not adequate. It is suggested to apply additional ketamin (i.v. and i.m.). With this procedure a satisfactory position of rest is obtained for more than two hours.

  16. The neuro-ophthalmologic signs of ciguatera poisoning: a case report.

    Science.gov (United States)

    Hamburger, H A

    1986-10-01

    Twenty-four hours after the ingestion of black grouper, lower-extremity paresthesias, left retrobulbar pain, pruritus, diarrhea, and urinary frequency developed in a 57-year-old woman. Over a three-month period, her symptoms gradually resolved completely. A review of the systemic and neuro-ophthalmologic manifestations of ciguatera poisoning is presented.

  17. The history of the evil eye and its influence on ophthalmology, medicine and social customs.

    Science.gov (United States)

    Bohigian, G H

    1997-01-01

    Belief in the evil eye is one of the oldest and most widespread superstitions in the world. The concept of the evil eye has influenced present day ophthalmology, medicine, and social customs. Oculus sinister (OS), the serpent and the staff of Asclepius, the symbol of RX, and many social customs are historically related to the evil eye.

  18. Ophthalmologic complications after intraoral local anesthesia: case report and review of literature

    NARCIS (Netherlands)

    Steenen, S.A.; Dubois, L.; Saeed, P.; de Lange, J.

    2012-01-01

    Intraoral administration of local anesthetics is one of the most common dental procedures. Ophthalmologic complications can occur after maxillary as well as mandibular local anesthetic injections and may be underreported and sometimes misinterpreted. A review of the literature from the years 1936-20

  19. The evaluation of uveitis in juvenile idiopathic arthritis (JIA) patients : are current ophthalmologic screening guidelines adequate?

    NARCIS (Netherlands)

    Reininga, J K; Los, L I; Wulffraat, N M; Armbrust, W

    2008-01-01

    OBJECTIVE: The aims of this study are to examine in our juvenile idiopathic arthritis (JIA) population: 1) the prevalence and characteristics of uveitis, 2) the complications and outcome of uveitis, 3) prognostic factors, and 4) the adequacy of the current ophthalmologic screening guidelines. METHOD

  20. The evaluation of uveitis in juvenile idiopathic arthritis (JIA) patients : are current ophthalmologic screening guidelines adequate?

    NARCIS (Netherlands)

    Reininga, J K; Los, L I; Wulffraat, N M; Armbrust, W

    2008-01-01

    OBJECTIVE: The aims of this study are to examine in our juvenile idiopathic arthritis (JIA) population: 1) the prevalence and characteristics of uveitis, 2) the complications and outcome of uveitis, 3) prognostic factors, and 4) the adequacy of the current ophthalmologic screening guidelines. METHOD

  1. [Ultrasound diagnostics in ophthalmology (standardized echography): part 1: principles and diseases of the eyeball].

    Science.gov (United States)

    Hasenfratz, G; Mardin, C

    2014-10-01

    Ultrasound diagnostics has been one of the most important additional diagnostic non-invasive techniques in ophthalmology for many decades and is essential for many intraocular and orbital diseases. When echographic investigations and analysis of the echograms obtained are correctly carried out, ultrasound diagnostics demonstrates a high degree of specificity and sensitivity.

  2. [Ultrasound diagnostics in ophthalmology (standardized echography): part 2: diseases of the orbit - ultrasound biomicroscopy diagnostics].

    Science.gov (United States)

    Hasenfratz, G; Mardin, C

    2014-11-01

    Ultrasound diagnostics have been one of the most important noninvasive supplementary diagnostic procedures in ophthalmology for many decades and are indispensable for many intraocular and orbital diseases. When the echography examination and analysis of the echograms obtained are correctly carried out, ultrasound diagnostics are characterized by a high measure of specificity and sensitivity.

  3. [Neuro-ophthalmology: the eye as a window to the brain].

    Science.gov (United States)

    Kesler, Anat

    2013-02-01

    Neuro-ophthalmology focuses on the diagnosis and treatment of visual disorders related to the neurological system rather than the globe itself. Being a subspecialty of both neurology and ophthalmology, it requires specialized training and expertise in diseases of the eye, brain, nerves and muscles. Commonly encountered pathologies in neuro-ophthalmology include: optic neuropathies (such as optic neuritis and ischemic optic neuropathy), visual field loss (transient, constant, unexplained), transient visual loss, unspecified visual disturbances, diplopia, abnormal eye movements, thyroid eye disease, myasthenia gravis, anisocoria, and eyelid abnormalities. The current issue of "Harefuah" is dedicated to contemporary knowledge in neuro-opthalmology, and spans from studies of neuromyelitis optica (NMO), ischemic optic neuropathies, and optic neuropathies induced by phosphodiesterase inhibitors, to the management of sight-threatening carotid-cavernous fistulas, and more. These studies emphasize the importance of an interdisciplinary treatment team consisting of a neuro-ophthalmologist, a neuro-radiologist, and sometimes, even a neuro-surgeon. Such an approach may prove to be beneficial to the patient, by optimizing follow-up and treatment decisions. This issue emphasizes how a correct and timely diagnosis is of paramount significance in patients with neuro-ophthalmological disorders.

  4. Contingent Valuation Analysis of an Otolaryngology and Ophthalmology Emergency Department: The Value of Acute Specialty Care.

    Science.gov (United States)

    Naunheim, Matthew R; Kozin, Elliot D; Sethi, Rosh K; Ota, H G; Gray, Stacey T; Shrime, Mark G

    2017-03-01

    Specialty emergency departments (EDs) provide a unique mechanism of health care delivery, but the value that they add to the medical system is not known. Evaluation of patient preferences to determine value can have a direct impact on resource allocation and direct-to-specialist care. To assess the feasibility of contingent valuation (CV) methodology using a willingness-to-pay (WTP) survey to evaluate specialty emergency services, in the context of an ophthalmology- and otolaryngology-specific ED. Contingent valuation analysis of a standalone otolaryngology and ophthalmology ED. Participants were English-speaking adults presenting to a dedicated otolaryngology and ophthalmology ED. The WTP questions were assessed using a payment card format, with reference to an alternative modality of treatment (ie, general ED), and were analyzed with multivariate regression. Validated WTP survey administered from October 14, 2014, through October 1, 2015. Sociodemographic data, level of distress, referral data, income, and WTP. A total of 327 of 423 (77.3%) ED patients responded to the WTP survey, with 116 ophthalmology and 211 otolaryngology patients included (52.3% female; mean [range] age, 46 [18-90] years). The most common reason for seeking care at this facility was a reputation for specialty care for both ear, nose, and throat (80 [37.9%]) and ophthalmology (43 [37.1%]). Mean WTP for specialty-specific ED services was $377 for ophthalmology patients, and $321 for otolaryngology patients ($340 overall; 95% CI, $294 to $386), without significant difference between groups (absolute difference, $56; 95% CI, $-156 to $43). Self-reported level of distress was higher among ear, nose, and throat vs ophthalmology patients (absolute difference, 0.47 on a Likert scale of 1-7; 95% CI, 0.10 to 0.84). Neither level of distress, income, nor demographic characteristics influenced WTP, but patients with higher estimates of total visit cost were more likely to have higher WTP (β coefficient

  5. Does open access in ophthalmology affect how articles are subsequently cited in research?

    Science.gov (United States)

    Lansingh, Van C; Carter, Marissa J

    2009-08-01

    To determine whether the concept of open access affects how articles are cited in the field of ophthalmology. Type of meta-analysis. Examination of 480 articles in ophthalmology in the experimental protocol and 415 articles in the control protocol. Four subject areas were chosen to search the ophthalmology literature in the PubMed database using the terms "cataract," "diabetic retinopathy," "glaucoma," and "refractive errors." Searching started in December of 2003 and worked back in time to the beginning of the year. The number of subsequent citations for equal numbers of both open access and closed access (by subscription) articles was quantified using the Scopus database and Google search engine. Number of authors, article type, country/region in which the article was published, language, and funding data were also collected for each article. A control protocol was also carried out to ascertain that the sampling method was not systematically biased by matching 6 ophthalmology journals (3 open access, 3 closed access) using their impact factors, and employing the same search methodology to sample open access and closed access articles. Number of citations. The total number of citations was significantly higher for open access articles compared to closed access articles for Scopus (mean 15.2 versus 11.5, P access was not a significant factor that explained the citation data. Author number, country/region of publication, subject area, language, and funding were the variables that had the most effect and were statistically significant. Control protocol results showed no significant difference between open and closed access articles in regard to number of citations found by Scopus: open access: mean = 17.8; SD (standard deviation) = 23.70; closed access: mean = 19.1; SD = 20.31; Mann-Whitney test, P = 0.730, Mann-Whitney U = 20584. Unlike other fields of science, open access thus far has not affected how ophthalmology articles are cited in the literature.

  6. Availability and quality of specialized ophthalmologic medical care: assessment by patients living in rural areas

    Directory of Open Access Journals (Sweden)

    S. V. Seraphimov

    2016-01-01

    Full Text Available The problem of restricted availability and quality of ophthalmologic medical care remains one of the main ones in the national healthcare. The article gives a comparative analysis of the opinions of rural residents of Leningrad region are in need of surgical treatment for ophthalmologic diseases, availability and quality of specialized medical care. A questionnaire was developed based on the methodology proposed by the Federal compulsory medical insurance Fund, through formal interviews of respondents of patients who received specialized ophthalmologic medical care in Leningrad region before opening of eye care hospitals for surgical treatment of cataract and glaucoma (148 patients and afterwards (320 patients. The results show that almost all patients who received treatment after the modernization of ophthalmologic offices are satisfied with the quality of medical care (completely satisfied – 91,3 %, quite satisfied – 7,6 %, which is significantly higher than the figures obtained in the survey of the patients before creation of specialized departments (t=3,6, p<0.05. Availability of medical care before reequipment of ophthalmologic departments in hospitals satisfied 62.8 % of respondents, and after the organization of activities of eye care hospitals – 75, 3 % (t=2,8, p<0.05. However, despite the new form of organization of medical aid, 27.5 % of the respondents are still not satisfied with its transport accessibility. Thus, patients receiving operative treatment of cataract are generally satisfied with the availability and quality of their medical services. Higher ratings of availability and quality of specialized eye medical care were received after opening of eye care hospitals for surgical treatment of cataract and glaucoma in Leningrad region.

  7. Ophthalmologic manifestations of focal dermal hypoplasia (Goltz syndrome): A case series of 18 patients.

    Science.gov (United States)

    Gisseman, Jordan D; Herce, Honey H

    2016-03-01

    Focal Dermal Hypoplasia (FDH) or Goltz syndrome is a rare multi-system disorder with cutaneous, ocular, dental, and skeletal anomalies due to dysplasia of mesoectodermal derived tissues. It is an X-linked inheritance syndrome caused by mutations in the PORCN gene. This study is aimed to investigate the ocular findings in patients with Goltz syndrome. To date, there have been a limited number of case reports on the ocular manifestations of FDH. This is a prospective, non-consecutive, observational case series. Prospective ophthalmologic evaluation was performed on 18 patients with confirmed genetic testing for FDH, Goltz Syndrome, as a component of a larger multi-subspecialty study to better characterize the findings of this condition. Special attention was placed on evaluating the incidence of anophthalmia, microphthalmia, colobomas (iris, optic nerve, and/or retinal), cataracts, nystagmus, and strabismus. A complete ophthalmologic exam was done on all the patients. The mean patient age was 12.8 years (1-55 years). Eighty-nine percent were female and 77% (14/18) of patients had some form of an ophthalmologic manifestation of the condition. Ophthalmological findings included chorioretinal colobomas (61%), iris colobomas (50%), microphthalmia (44%), anophthalmia (11%), cataracts (11%), and conjunctival and eyelid papillomas (5%). Nystagmus was present in 33% and strabismus in 22% of the patients. Visual acuity ranged from 20/20 to no light perception. This study demonstrates a higher incidence of ophthalmologic manifestations as previously reported (77% vs. 40%). To our knowledge, this is the largest case series reported in the literature with 18 patients.

  8. Ophthalmologic impairment during adulthood in central congenital hypoventilation syndrome: a longitudinal cohort analysis of nine patients.

    Science.gov (United States)

    Boulanger-Scemama, Elise; Fardeau, Christine; Straus, Christian; Simon, Claude; Touitou, Valérie; Touhami, Sara; Amini, Maryam; Similowski, Thomas; LeHoang, Phuc

    2014-12-01

    Congenital central hypoventilation syndrome (CCHS) is a rare dysgenetic form of neurocristopathy associated with dysfunction of the autonomic nervous system. Ophthalmologic abnormalities are reported in CCHS children, and range from pupillary and iris abnormalities to ptosis, strabismus and convergence deficiency. Since earlier CCHS diagnosis and multidisciplinary management, combined with improved ventilatory support techniques, the lifespan of children with CCHS has been considerably lengthened. The oldest of them have now reached adult age and we report in this study the results of their ophthalmologic examination. Nine CCHS adult patients were prospectively included during a 14-month period. Each patient underwent complete ophthalmologic examination, static pupillometry with scotopic and photopic pupillary diameter (PD) measures, Humphrey 24-2 visual field analysis, macular OCT and complete orthoptic assessment including a Hess-Lancaster test. Ophthalmologic abnormalities were found in six of the nine patients (66%). The main features were strabismus in six patients (66%). Four patients (44%) displayed abnormal pupillary function, with a decrease in average scotopic PD (3.8 ± 1.4 mm), average photopic PD (3.5 ± 1.2 mm), and average percentage of pupillary constriction (7.6 ± 8.5%). Three patients (33%) exhibited iris abnormalities such as iris atrophy, smooth iris surface and atrophic sphincter. This study allowed the description of ophthalmologic abnormalities occurring in CCHS in a series of adult patients, thus improving current knowledge of the disease. The prevalence of pupillary and iris lesions were lower than those observed in a series of children, suggesting that they could be considered as systemic disease severity markers.

  9. A historical outline of Greek ophthalmology from the Hellenistic period up to the establishment of the first universities.

    Science.gov (United States)

    Lascaratos, J; Marketos, S

    1988-01-01

    The writers examine the course of Greek ophthalmology from the Hellenistic period to the foundation of the first universities (19th century). In particular, the study refers to Galen, Antyllus, the Byzantine doctors Oribasius, Aetius of Ameda, Paul of Aegina, Alexander of Tralles, Nonnus Theophanes, Theophilus Protospatharius, Michael Psellos, Meletius Monachus, Nemesius bishop of Emeses and John Actuarius. The practice of empirical ophthalmology during the Ottoman domination of Greece is also examined, as is the earliest available evidence of modern Greek ophthalmological knowledge, deriving from the Ionian Islands.

  10. Publication times, impact factors, and advance online publication in ophthalmology journals.

    Science.gov (United States)

    Chen, Haoyu; Chen, Chun Hui; Jhanji, Vishal

    2013-08-01

    Publication speed of peer-reviewed journals may play a major role in early dissemination of knowledge and may raise the citation index. In this study, we evaluated the publication speed of ophthalmology journals. Observational study. Observational study of bibliometric data in published ophthalmology journals. A list of ophthalmic journals featured in the 2010 Journal Citation Report was obtained on September 1, 2011. A total of 12 articles were chosen randomly from each of these journals published between January and December 2010. Median publication time and interquartile range (IQR) were obtained from the full texts of the published articles. Time lag between submission and revision, acceptance, and publication of the manuscripts was calculated. Correlation between publication time lag and journal impact factor as well as advance online publication was analyzed. A total of 51 ophthalmic journals were included. There was no statistically significant difference in the impact factors of journals based on their reporting of submission, revision, or acceptance times of the manuscripts (both P>0.05, Wilcoxon test). The median peer review and publication time of all ophthalmology journals was 133 days (IQR, 100.5-171.5) and 100 days (IQR, 62.9-166.3), respectively. There was no correlation between the journal impact factors and publication time lag (Spearman correlation). Approximately half of the ophthalmology journals (n = 26; 50.98%) published online in advance. Journals with advance online publication had higher impact factors compared with those without this feature (median, 1.692 [IQR, 1.05-2.80] vs. 1.02 [0.39-1.53]; P = 0.015, Mann-Whitney U test). For journals with advance online publication, the median time from acceptance to advance online publication (74.3 days [IQR, 48.3-115 days]) was significantly shorter than the median time between acceptance and print publication (170.75 days [IQR, 101.4-217 days]; Pjournals was not correlated with journal impact

  11. Procedural aspects of the organization of the comprehensive European Board of Ophthalmology Diploma examination

    OpenAIRE

    Mathysen, Danny G.P.; Ringens, Peter J; Edoardo Midena; Artur Klett; Gordana Sunaric-Mégevand; Rafael Martinez-Costa; Denise Curtin; Marie-José Tassignon; Wagih Aclimandos; Catherine Creuzot-Garcher; Christina Grupcheva

    2016-01-01

    The comprehensive European Board of Ophthalmology Diploma (EBOD) examination is one of 38 European medical specialty examinations. This review aims at disclosing the specific procedures and content of the EBOD examination. It is a descriptive study summarizing the present organization of the EBOD examination. It is the 3rd largest European postgraduate medical assessment after anaesthesiology and cardiology. The master language is English for the Part 1 written test (knowledge test with 52 mo...

  12. Can children undergoing ophthalmologic examinations under anesthesia be safely anesthetized without using an IV line?

    OpenAIRE

    Vigoda M; Latiff A; Murray T; Tutiven J; Berrocal A; Gayer S

    2011-01-01

    Michael M Vigoda, Azeema Latiff, Timothy G Murray, Jacqueline L Tutiven, Audina M Berrocal, Steven GayerBascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USAPurpose: To document that with proper patient and procedure selection, children undergoing general inhalational anesthesia for ophthalmologic exams (with or without photos, ultrasound, laser treatment, peri-ocular injection of chemotherapy, suture removal, and/or replacement of ocular prosthesis) can b...

  13. The invention of gonioscopy by Alexios Trantas and his contribution to ophthalmology.

    Science.gov (United States)

    Kalantzis, G; Georgalas, I; Tsiamis, C; El-Hindy, N; Poulakou-Rebelakou, E

    2015-01-01

    Gonioscopy is a technique used to examine structures in the anterior chamber angle (the fluid filled space inside the eye between the iris and the innermost layer of the cornea, the endothelium). It is an essential tool in ophthalmic practice, particularly in the diagnosis of glaucoma. In 1899, the Greek ophthalmologist Alexios Trantas was the first to visualise the angle in vivo and coined the term 'gonioscopy'. He made a number of other important contributions to ophthalmology.

  14. A Randomized Controlled Study of Art Observation Training to Improve Medical Student Ophthalmology Skills.

    Science.gov (United States)

    Gurwin, Jaclyn; Revere, Karen E; Niepold, Suzannah; Bassett, Barbara; Mitchell, Rebecca; Davidson, Stephanie; DeLisser, Horace; Binenbaum, Gil

    2017-08-03

    Observation and description are critical to the practice of medicine, and to ophthalmology in particular. However, medical education does not provide explicit training in these areas, and medical students are often criticized for deficiencies in these skills. We sought to evaluate the effects of formal observation training in the visual arts on the general and ophthalmologic observational skills of medical students. Randomized, single-masked, controlled trial. Thirty-six first-year medical students, randomized 1:1 into art-training and control groups. Students in the art-training group were taught by professional art educators at the Philadelphia Museum of Art, during 6 custom-designed, 1.5-hour art observation sessions over a 3-month period. All subjects completed pre- and posttesting, in which they described works of art, retinal pathology images, and external photographs of eye diseases. Grading of written descriptions for observational and descriptive abilities by reviewers using an a priori rubric and masked to group assignment and pretesting/posttesting status. Observational skills, as measured by description testing, improved significantly in the training group (mean change +19.1 points) compared with the control group (mean change -13.5 points), P = 0.001. There were significant improvements in the training vs. control group for each of the test subscores. In a poststudy questionnaire, students reported applying the skills they learned in the museum in clinically meaningful ways at medical school. Art observation training for first-year medical students can improve clinical ophthalmology observational skills. Principles from the field of visual arts, which is reputed to excel in teaching observation and descriptive abilities, can be successfully applied to medical training. Further studies can examine the impact of such training on clinical care. Copyright © 2017 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  15. Drug Utilization Study in Outpatient Ophthalmology Department of Government Medical College Jammu

    OpenAIRE

    Meenakshi Nehru, K. Kohli, B. Kapoor, P. Sadhotra, V. Chopra, R. Sharma

    2005-01-01

    The present study was undertaken to assess the patterns of prescription and drug utilization bymeasuring WHO delineated drug use indicators. This study was conducted in the PostgraduateDepartment of Pharmacology and Therapeutics in collaboration with the Postgraduate Departmentof Ophthalmology Govt. Medical College Hospital, Jammu. Total number of prescriptions analyzedwere 440 , in which total of 822 drugs were prescribed. Analysis of the prescriptions showed thataverage number of drugs per ...

  16. The Study of Ophthalmologic Involvement in 28 Behcet’s Syndrome Patients

    Directory of Open Access Journals (Sweden)

    M.M. Panahi

    2004-04-01

    Full Text Available Behcet’s syndrome is a generalized vasculitis with unknown cause. Acute recurrent iritis , retinal vasculitis , retinal hemorrhage , macular edema , retinal necrosis , ischemic optic neuropathy and vitritis are the most common ophthalmologic involvement. The aim of this study was to determine the frequency of ophthalmologic involvement in patients with Behcet syndrome who referred to ophthalmology clinic of Imam Khomeini hospital in Hamadan city during May 2002-February 2003. This research was a prospective cross-sectional study on 28 patients suffering from Behcet’s syndrome . All of the patients were examined by slit lamp and direct and indirect fundoscopy and evaluation of visual acuity. The required information from each patiens was recorded in a checklist. 19 patients were male and 9 patients were female. The most common age of the patients was the 4th decade. The first sign was oral involvement (64.3%. Ophthalmologic involvement was observed in 20 patients (71% overall. Cataract was in 8 patients , pigmentation of lens was in 3 patients and post subcapsular cataract in 2 patients, post synechia was in 11 patients , Ant.uveitis was in 2 patints, post uveitis was in 3 patients and panuveitis was in 8 patients , 3 patients had hypopyone , 11 patients had vitritis , 8 patients had ischemic optic neuropathy , 8 patients had retinal necrosis , 8 patients had retinal vasculitis , 5 patients had retinal hemorrhage and 5 patients had macular edema. Visual acuity of 5 patients was NLP (blindness due to Behcet’s syndrome. This study showed that Ant. uveitis and cataract had the high frequency and post. uveitis and panuveitis had low frequency and other manifestations of subjects approximately were equal compared with other reports.

  17. Ophthalmologic findings in an 18-month-old boy with focal dermal hypoplasia.

    Science.gov (United States)

    Young, Marielle P; Sawyer, Briana L; Hartnett, M Elizabeth

    2014-04-01

    Focal dermal hypoplasia is a rare X-linked dominant disorder with in utero lethality in males. Affected patients have been reported to have several different mutations in the PORCN gene on chromosome Xp11.23. Dysplastic mesodermal and ectodermal tissue causes clinical findings in the skin, skeleton, teeth, central nervous system, and eyes of affected patients. We describe the ophthalmologic findings in an 18-month-old boy with mosaicism of a novel mutation in PORCN.

  18. Teaching Neuro-Ophthalmology in the Asia-Pacific Region and China: A Personal Perspective.

    Science.gov (United States)

    Crompton, John

    2015-12-01

    Over the last 30 years, I have been involved in a number of projects helping to educate and train local ophthalmologists in many parts of Asia and the Pacific Islands, which lack adequate training and service in neuro-ophthalmology. In this article, I offer an overview of a number of different teaching initiatives and offer practical suggestions to anyone who might wish to become involved.

  19. Ophthalmological screening of a paediatric cochlear implant population: a retrospective analysis and 12-year follow-up.

    LENUS (Irish Health Repository)

    Falzon, K

    2010-06-01

    To determine the nature and prevalence of ophthalmological findings for a cohort of children in a paediatric cochlear implant program and to assist the clinician in devising an investigative plan for this population.

  20. International Council of Ophthalmology: Refocusing Ophthalmic Education in the Asia-Pacific Region and Beyond.

    Science.gov (United States)

    Golnik, Karl; Mayorga, Eduardo; Spivey, Bruce; Ritch, Robert; Gauthier, Tina-Marie

    2012-01-01

    The International Council of Ophthalmology (ICO) is a global organization with a regional focus. Working in partnership with supranational and ICO member societies, the ICO is building a "World Alliance for Sight" to improve access to the highest-quality eye care worldwide. Designed to preserve and restore vision on an international scale, the ICO initiative, "Refocusing Ophthalmic Education," enhances ophthalmic education of residents, subspecialists, medical students, and allied eye care personnel by redefining the most effective ways to teach and in creating beneficial educational opportunities. The "Teaching the Teachers" program helps ophthalmic educators incorporate more effective methods of training and continuing professional development to meet societal needs, achieved in part through regional courses for residency program directors; symposia, and keynote talks presented by ICO's World Ophthalmology Educational Colloquium, Conferences for Ophthalmic Educators, and ophthalmic surgical competency rubrics. Recognizing that standardized curricula are essential for consistent ophthalmic education, the ICO has developed a curricular framework whereby goals, expectations, knowledge base, competencies, and technical training are delineated. The ICO is defining worldwide models of team training and compiling best practice, which will include training-program accreditation to ensure improvement in the education of ophthalmologists. International Council of Ophthalmology Web-based teaching courses, a Webinar Network, and a technology blog further support information and communication technologies for teaching and learning. At the ICO's Center for Ophthalmic Educators (educators.icoph.org), trainers will find valuable teaching resources in multiple languages as well as ways to share ideas and collaborate with peers and other ophthalmic educators.

  1. Effects of hand massage on anxiety in patients undergoing ophthalmology surgery using local anesthesia

    Directory of Open Access Journals (Sweden)

    Jafar Rafiei Kiasari

    2012-08-01

    Full Text Available Introduction: Anxiety is a common disorder in patients before surgery. Inappropriately managed anxiety can cause psychological and physiological reactions and will affect the process of surgery and recovery. Therefore, this study examined the effects of hand mas-sage on anxiety in patients undergoing ophthalmology surgery using local anesthesia. Methods: In this interventional study, 52 patients who were supposed to undergo oph-thalmology surgery using local anesthesia were studied. Patients were randomly as-signed to two groups of intervention, who received hand massage before surgery (n = 27 and control (n = 25. Massaging lasted for 5 minutes (2.5 minutes on each hand before surgery. Stroking and scrubbing methods were performed by 2 trained research-ers. Anxiety level, blood pressure, heart rate, and respiratory rate were measured before and after the intervention in both groups. Anxiety was evaluated using Spielberger State-Trait Anxiety Inventory. Data was analyzed by chi-square, independent samples t-test, and paired t-test. Results: There were no significant differences in mean anxiety, systolic blood pressure, diastolic blood pressure, heart rate, and respiratory rate between the two groups before the intervention (p > 0.05. However, there was a significant differenc in the mean stress level between the two groups after the intervention (p 0.05. Conclusion: Our findings suggested that 5 minutes of hand massage before ophthalmology surgery (under local anesthesia could reduce anxiety. Therefore, this method can be used to increase patient comfort and reduce anxiety before surgical interventions.

  2. Enhancing Medical Student Education by Implementing a Competency-Based Ophthalmology Curriculum.

    Science.gov (United States)

    Succar, Tony; McCluskey, Peter; Grigg, John

    2017-01-01

    To evaluate innovative educational strategies that help optimize ophthalmology teaching in a crowded medical curriculum. The knowledge acquisition and perceptions of medical students undertaking the revised competency-based curriculum were compared with the prior content-based curriculum within the Sydney Medical Program. A mixed-methods research design was employed to include both quantitative and qualitative dimensions in evaluating the revised curriculum with medical students (n = 328) undergoing their ophthalmology rotation. Quantitative evaluation was performed with a 20-item multiple choice pre- and post-test of ophthalmic knowledge. A 12-month follow-up test was readministered to compare the long-term retention rate of graduates. Qualitative evaluation was measured with student satisfaction questionnaires. In the original curriculum there was an improvement of 19.9% from pre- to post-test scores [2.15; 95% confidence interval (CI), 1.35-2.94; P higher than students from the original curriculum (1.56; 95% CI, 0.42-2.71; P = 0.008). In addition, qualitative feedback also improved, with the rotation being highly valued. The revised ophthalmic curriculum resulted in an increase in academic performance and a higher degree of student satisfaction. Given the gradual decline of ophthalmic education in the standard medical school curriculum, our results are timely in providing guidance for minimum ophthalmic curriculum exposure and strategies to improve ophthalmic education in medical schools. Copyright© 2017 Asia-Pacific Academy of Ophthalmology.

  3. Ophthalmology hospital wards contamination to pathogenic free living Amoebae in Iran.

    Science.gov (United States)

    Lasjerdi, Zohreh; Niyyati, Maryam; Lorenzo-Morales, Jacob; Haghighi, Ali; Taghipour, Niloofar

    2015-09-01

    The present study was conducted to determine the occurrence of potentially pathogenic free-living amoeba in ophthalmology wards in reference hospitals in Iran. Since an increasing number of Acanthamoeba Keratitis cases after eye surgery and eye trauma have been recently observed in this country, it could be possible that the disinfection procedures undertaken in the clinical setting may not have a good hygiene and disinfection procedures, hence the aim of this study. Therefore, 42 dust and biofilm samples were collected from different areas of ophthalmology wards and checked for the presence of FLA using morphological criteria, PCR based analysis and DNA sequencing. Of the 42 samples from dust and biofilm sources, 18(42.86%) isolates were found to contain FLA and 12(92.3%) isolates belonged to Acanthamoeba T4 genotype. Isolation of the pathogenic genotype T4 from medical instruments, including slit lamp in corneal wards, may be a threat for patients undergoing eye surgery in these wards. Other FLA isolated in this study included Acanthamoeba genotype T5, Vahlkampfia sp, Naegleria australiensis, Vermamoeba vermiformis and Echinamoeba exudans. To our knowledge, this is the first report of the presence of potentially pathogenic FLA in ophthalmology wards in Iran. Improved disinfection methods and monitoring of hospitals ward are thus necessary in this area in order to minimize the risk of infection in patients.

  4. Resolvins and aliamides: lipid autacoids in ophthalmology – what promise do they hold?

    Directory of Open Access Journals (Sweden)

    Hesselink JMK

    2016-09-01

    Full Text Available Jan M Keppel Hesselink,1 Flavia Chiosi,2 Ciro Costagliola2 1University of Witten/Herdecke, Witten, Germany; 2Eye Clinic, Department of Medicine and Health Sciences, University of Molise, Campobasso, Italy Abstract: Resolvins are a novel class of lipid-derived endogenous molecules (autacoids with potent immunomodulating properties, which regulate the resolution phase of an active immune response. These modulating factors are locally produced, influencing the function of cells and/or tissues, which are produced on demand and subsequently metabolized in the same cells and/or tissues. This review is focused on certain lipid autacoids with putative relevance for ophthalmology in general and for dry eye more specifically. We also briefly investigate the concept of aliamides and the role of palmitoylethanolamide in ophthalmology, and analyze in more detail the putative role and the preclinical and clinical development of resolvins as emerging treatments for dry eye and related disorders, with a focus on one of the lead resolvin derivatives – RX-10045. Keywords: resolvins, autacoids, aliamides, dry eye, palmitoylethanolamide, inflammation, ophthalmology, protection

  5. Facing the challenges in ophthalmology clerkship teaching: Is flipped classroom the answer?

    Science.gov (United States)

    Lin, Ying; Zhu, Yi; Chen, Chuan; Wang, Wei; Chen, Tingting; Li, Tao; Li, Yonghao; Liu, Bingqian; Lian, Yu; Lu, Lin; Zou, Yuxian; Liu, Yizhi

    2017-01-01

    Recent reform of medical education highlights the growing concerns about the capability of the current educational model to equip medical school students with essential skills for future career development. In the field of ophthalmology, although many attempts have been made to address the problem of the decreasing teaching time and the increasing load of course content, a growing body of literature indicates the need to reform the current ophthalmology teaching strategies. Flipped classroom is a new pedagogical model in which students develop a basic understanding of the course materials before class, and use in-class time for learner-centered activities, such as group discussion and presentation. However, few studies have evaluated the effectiveness of the flipped classroom in ophthalmology education. This study, for the first time, assesses the use of flipped classroom in ophthalmology, specifically glaucoma and ocular trauma clerkship teaching. A total number of 44 international medical school students from diverse background were enrolled in this study, and randomly divided into two groups. One group took the flipped glaucoma classroom and lecture-based ocular trauma classroom, while the other group took the flipped ocular trauma classroom and lecture-based glaucoma classroom. In the traditional lecture-based classroom, students attended the didactic lecture and did the homework after class. In the flipped classroom, students were asked to watch the prerecorded lectures before the class, and use the class time for homework discussion. Both the teachers and students were asked to complete feedback questionnaires after the classroom. We found that the two groups did not show differences in the final exam scores. However, the flipped classroom helped students to develop skills in problem solving, creative thinking and team working. Also, compared to the lecture-based classroom, both teachers and students were more satisfied with the flipped classroom

  6. Ophthalmologic Baseline Characteristics and 2-Year Ophthalmologic Safety Profile of Pramipexole IR Compared with Ropinirole IR in Patients with Early Parkinson’s Disease

    Directory of Open Access Journals (Sweden)

    William Seiple

    2016-01-01

    Full Text Available Background. Parkinson’s disease (PD progressively affects dopaminergic neurotransmission and may affect retinal dopaminergic functions and structures. Objective. This 2-year randomized, open-label, parallel-group, flexible-dose study, NCT00144300, evaluated ophthalmologic safety profiles of immediate-release (IR pramipexole and ropinirole in patients with early idiopathic PD with ≤6 months’ prior dopamine agonist exposure and without preexisting major eye disorders. Methods. Patients received labeled IR regimens of pramipexole (n=121 or ropinirole (n=125 for 2 years. Comprehensive ophthalmologic assessments (COA included corrected acuity, Roth 28-color test, slit-lamp biomicroscopy, intraocular pressure, computerized visual field test, fundus photography, and electroretinography. Results. At baseline, we observed retinal pigmentary epithelium (RPE hypopigmentation not previously reported in PD patients. The estimated relative risk of 2-year COA worsening with pramipexole versus ropinirole was 1.07 (95% CI: 0.71–1.60. Mean changes from baseline in Unified Parkinson’s Disease Rating System parts II+III total scores (pramipexole: 1 year, −4.1±8.9, and 2 years, −0.7±10.1, and ropinirole: 1 year, −3.7±8.2, and 2 years, −1.7±10.5 and Hoehn–Yahr stage distribution showed therapeutic effects on PD symptoms. Safety profiles were consistent with labeling. Conclusions. The risk of retinal deterioration did not differ in early idiopathic PD patients receiving pramipexole versus ropinirole. RPE hypopigmentation at baseline was not previously reported in this population. This trial is registered with NCT00144300.

  7. Ophthalmologic Baseline Characteristics and 2-Year Ophthalmologic Safety Profile of Pramipexole IR Compared with Ropinirole IR in Patients with Early Parkinson's Disease

    Science.gov (United States)

    Jennings, Danna; Borchert, Leona; Canale, Lee; Fagan, Nora

    2016-01-01

    Background. Parkinson's disease (PD) progressively affects dopaminergic neurotransmission and may affect retinal dopaminergic functions and structures. Objective. This 2-year randomized, open-label, parallel-group, flexible-dose study, NCT00144300, evaluated ophthalmologic safety profiles of immediate-release (IR) pramipexole and ropinirole in patients with early idiopathic PD with ≤6 months' prior dopamine agonist exposure and without preexisting major eye disorders. Methods. Patients received labeled IR regimens of pramipexole (n = 121) or ropinirole (n = 125) for 2 years. Comprehensive ophthalmologic assessments (COA) included corrected acuity, Roth 28-color test, slit-lamp biomicroscopy, intraocular pressure, computerized visual field test, fundus photography, and electroretinography. Results. At baseline, we observed retinal pigmentary epithelium (RPE) hypopigmentation not previously reported in PD patients. The estimated relative risk of 2-year COA worsening with pramipexole versus ropinirole was 1.07 (95% CI: 0.71–1.60). Mean changes from baseline in Unified Parkinson's Disease Rating System parts II+III total scores (pramipexole: 1 year, −4.1 ± 8.9, and 2 years, −0.7 ± 10.1, and ropinirole: 1 year, −3.7 ± 8.2, and 2 years, −1.7 ± 10.5) and Hoehn–Yahr stage distribution showed therapeutic effects on PD symptoms. Safety profiles were consistent with labeling. Conclusions. The risk of retinal deterioration did not differ in early idiopathic PD patients receiving pramipexole versus ropinirole. RPE hypopigmentation at baseline was not previously reported in this population. This trial is registered with NCT00144300. PMID:28078162

  8. Creation of an Accurate Algorithm to Detect Snellen Best Documented Visual Acuity from Ophthalmology Electronic Health Record Notes.

    Science.gov (United States)

    Mbagwu, Michael; French, Dustin D; Gill, Manjot; Mitchell, Christopher; Jackson, Kathryn; Kho, Abel; Bryar, Paul J

    2016-05-04

    Visual acuity is the primary measure used in ophthalmology to determine how well a patient can see. Visual acuity for a single eye may be recorded in multiple ways for a single patient visit (eg, Snellen vs. Jäger units vs. font print size), and be recorded for either distance or near vision. Capturing the best documented visual acuity (BDVA) of each eye in an individual patient visit is an important step for making electronic ophthalmology clinical notes useful in research. Currently, there is limited methodology for capturing BDVA in an efficient and accurate manner from electronic health record (EHR) notes. We developed an algorithm to detect BDVA for right and left eyes from defined fields within electronic ophthalmology clinical notes. We designed an algorithm to detect the BDVA from defined fields within 295,218 ophthalmology clinical notes with visual acuity data present. About 5668 unique responses were identified and an algorithm was developed to map all of the unique responses to a structured list of Snellen visual acuities. Visual acuity was captured from a total of 295,218 ophthalmology clinical notes during the study dates. The algorithm identified all visual acuities in the defined visual acuity section for each eye and returned a single BDVA for each eye. A clinician chart review of 100 random patient notes showed a 99% accuracy detecting BDVA from these records and 1% observed error. Our algorithm successfully captures best documented Snellen distance visual acuity from ophthalmology clinical notes and transforms a variety of inputs into a structured Snellen equivalent list. Our work, to the best of our knowledge, represents the first attempt at capturing visual acuity accurately from large numbers of electronic ophthalmology notes. Use of this algorithm can benefit research groups interested in assessing visual acuity for patient centered outcome. All codes used for this study are currently available, and will be made available online at https://phekb.org.

  9. Risks and Management of Ophthalmologic Nursing%眼科护理风险与管理

    Institute of Scientific and Technical Information of China (English)

    金晓丹; 张燕; 章灵芝; 戴杰

    2016-01-01

    目的探讨眼科护理中风险因素及防范对策。方法通过查阅2013年1月至2015年12月的眼科护理病历和护理记录单、警讯事件报告记录、不良事件报告记录、药品不良反应上报记录及患者建议投诉等记录,分析归纳影响眼科护理的风险因素。结果护理相关、疾病本身、患者自身、环境相关、药物相关、管理相关及其他相关因素等均是眼科护理工作中所存在的风险因素。结论影响眼科护理质量的因素很多,护理人员要提高自我的风险防范意识,严格执行各项规章制度,不断增强医德医风,不断提高专科理论与业务水平,重视应急能力培训,加强护患沟通、健康宣教和心理护理,建立药物分类提醒和护理标识警示,做好感染预防,实行风险控制管理,才能有效减少不良事件的发生,保证患者安全从而减少医疗纠纷、提高眼科护理质量。%Objective To discuss the risk factors of ophthalmologic nursing and preventive measures.Methods Analyzed and summarized the risk factors of ophthalmologic nursing by reviewing the medical records of ophthalmologic nursing, reports of sentinel events and adverse events as well as adverse drug reactions reports and patients' recommendations and complaints from January 2013 to December 2015.Results Nursing, the disease itself, patients themselves, environment, drug, management and other related factors were all relevant risk factors for ophthalmologic nursing.Conclusions There were many factors that influenced the quality of ophthalmologic nursing. Nurses should increase self-awareness of risks, fully implement rules and regulations, and constantly enhance their ethics and theoretical and professional skills. They should pay more attention to the training of emergency response capacity, strengthen nurse-patient communication, enhance health education and psychological care and establish drug classification sign

  10. Ophthalmology case

    Directory of Open Access Journals (Sweden)

    Fábio Barroso

    2017-07-01

    Discussion: The diagnosis of limbal dermoids is established by the presence of a yellow/white solid tumour located at the limbus. These lesions have been classified into three grades. The treatment for grade I pediatric limbal dermoids is initially conservative. In stages II and III, a combination of simple excision, lamellar keratoplasty, sutureless amniotic membrane and limbal stem cell tranplantation may be necessary. Prognosis is generally favourable.

  11. COMMUNITY OPHTHALMOLOGY

    African Journals Online (AJOL)

    2016-11-04

    Nov 4, 2016 ... Methods/Patients/Participants: This is a cross sectional study done between March and April .... hospitals.[4-7] The knowledge and management of eye diseases is poor which is ..... Diabetic retinopathy. 2 (1.2). Migraine. 2 (1.2).

  12. GENERAL OPHTHALMOLOGY

    African Journals Online (AJOL)

    or mental violence, injury or abuse, neglect or negligent treatment, and maltreatment or ... morbidity, and the importance of ocular health education as a form of preventive ... Teenager Presenting to the Outpatient Clinic with Refractive Error. Olufunmilola ..... invited key note addresses, reviews, media coverage, or any other.

  13. Cataract surgery education in member countries of the European Board of Ophthalmology.

    Science.gov (United States)

    Muttuvelu, Danson V; Andersen, Carl Uggerhøj

    2016-06-01

    To address the use of and knowledge about skills assessment and competency-based training in cataract surgery in European Board of Ophthalmology (EBO) member countries. A survey was emailed directly to all directors of the European societies in ophthalmology. The survey included queries about criteria to undergo training in cataract surgery, regulation of education in cataract surgery, and skills assessment and training methods. In addition, all Danish Eye Departments were further asked to what extent they find assessment tools useful, if competency-based training in cataract surgery would be an improvement, and if an assessment tool would be considered for use in future training of cataract surgeons. Training in cataract surgery in EBO countries is very diverse; although some EBO countries consider it mandatory in residency, most do not. In EBO countries where training is mandatory and regulated by the local health authority, the use of skills assessment tools and competency-based education are more prevalent (e.g., U.K., Ireland, Switzerland, and the Netherlands). In Denmark, training in cataract surgery is not mandatory, and none of the eye departments used assessment scores to evaluate their trainees; 63% did not believe that using assessment tools would improve the outcome of surgical training, and less than one-third would consider frequent use of assessment tools in the future. General unawareness and scepticism toward objective structured assessment of technical skills and a considerable heterogeneity in concept and organization of training in cataract surgery across EBO countries is an issue to address. Copyright © 2016 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights reserved.

  14. Bridging the gap: theory-based design of a microsurgical skills course for ophthalmology residents.

    Science.gov (United States)

    Koukkoulli, Antigoni; Chandra, Aman; Sheth, Hithen; Okhravi, Narciss; Verma, Seema; Sullivan, Paul; Ezra, Daniel G

    2015-01-01

    Although theory-based schemes for course design are widely used in educational settings, making use of cognitive theory in the design of surgical skills courses in ophthalmology is rare. The primary aim of this study is to describe the application of instructional design, an established theory-based approach in course design, to the development of a surgical skills course for ophthalmology residents. The secondary aim of this study is to assess the educational effect of this theory-based course. A 1-day skills course was designed according to Gagné׳s events of instruction model, which was employed as a template for the instructional sequence of learning steps. Skills acquisition following the implementation of the model was measured with precourse and postcourse assessments. Moorfields Eye Hospital organized the 1-day annual intermediate surgical skills course, which was hosted at the Royal College of Ophthalmologists' microsurgical skills laboratory. A total of 20 ophthalmology residents of Moorfields Eye Hospital participated in the study. A 1-day surgical skills course was formulated according to the instructional design principles outlined. The 4 objectives of the course (corneal suturing, corneal gluing, intravitreal injections, and eyelid suturing) were addressed in a parallel fashion as to allow for multiple objectives to be processed simultaneously, in the context of the instructional design sequence. Assessments demonstrated significant improvement in skills acquisition for the 4 course objectives. Instructional design is a valuable tool for planning effective surgical training courses as it is portable, allowing its application to a wide variety of outcomes and settings, and its terminology is simple and understandable to those working in clinical education. Copyright © 2015 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.

  15. Microscopic alterations in silicone tubes surface after application of ophthalmological lubricants

    Directory of Open Access Journals (Sweden)

    Jacqueline Sousa

    2015-02-01

    Full Text Available Objective: To identify microscopic morphological alterations in the surface of silicone tubes used for intubation of the lachrymal system after exposure to ophthalmological lubricants. Methods: Experimental, descriptive and longitudinal study consisted of the application of ophthalmological lubricants in silicone tubes. The tubes were divided in: Group 1 (Cylocort®, 2 (Epitezan®, 3 (Labcaína®, 4 (Liposic®, 5 (Maxinom® and 6 (Vista Gel®. One tube was not exposed to any lubricant, used as control. The tubes were observed and photographed after 2 hours, 30 days, 45 days before and after cleaning the surface and lumen. The following aspects were observed: surface (regularity, transparency, quantity, size and shape of the substances and lumen (obstruction. Results: Control: irregular surface with pores after 2 hours: Group 1 – irregular surface with presence of film; Groups 2, 3 and 5 – abundant and irregular quantity of ointment at the surface; Group 4 – discrete modification at the surface; Group 6 – growth of pigmented (brownish structures with filaments in the lumen, with discrete film in the surface. 30 Days: Groups 1, 4 and 5 – increase of the irregular superficial film; Group 2 – crust with notorious horizontal lines; Group 3 – diminution of the superficial film; Group 4 – crust less evident. Group 6 – increase of the structure seen with 2 hours of exposition, arboriform aspect. Forty-five days pre cleaning: Group 4 – diminution of the surface crust; Group 6 – expansion of the arboriform structure; unaltered findings in other groups. 45 days after cleaning: Groups 1 and 5 – light diminution of the surface crust; Groups 2, 3 and 4 – kept the modifications; Group 6 – the structure inside the lumen was not identified, clear surface, without evidence of film. Conclusions: Microscopic morphological alterations in the surface and lumen of silicone tubes can occur when those remain in contact with determined

  16. The QuantiFERON-TB Gold In-Tube Assay in Neuro-Ophthalmology.

    Science.gov (United States)

    Little, Leanne M; Rigi, Mohammed; Suleiman, Ayman; Smith, Stacy V; Graviss, Edward A; Foroozan, Rod; Lee, Andrew G

    2017-09-01

    Although QuantiFERON-TB Gold In-Tube (QFT-GIT) testing is regularly used to detect infection with Mycobacterium tuberculosis, its utility in a patient population with a low risk for tuberculosis (TB) has been questioned. The following is a cohort study analyzing the efficacy of QFT-GIT testing as a method for detection of active TB disease in low-risk individuals in a neuro-ophthalmologic setting. Ninety-nine patients from 2 neuro-ophthalmology centers were identified as having undergone QFT-GIT testing between January 2012 and February 2016. Patients were divided into groups of negative, indeterminate, and positive QFT-GIT results. Records of patients with positive QFT-GIT results were reviewed for development of latent or active TB, as determined by clinical, bacteriologic, and/or radiographic evidence. Of the 99 cases reviewed, 18 patients had positive QFT-GIT tests. Of these 18 cases, 12 had documentation of chest radiographs or computed tomography which showed no evidence for either active TB or pulmonary latent TB infection (LTBI). Four had chest imaging which was indicative of possible LTBI. None of these 18 patients had symptoms of active TB and none developed active TB within the follow-up period. Based on our results, we conclude that routine testing with QFT-GIT in a low-risk cohort did not diagnose active TB infection. We do not recommend routine QFT-GIT testing for TB low-risk individuals, as discerned through patient and exposure history, ocular examination, and clinical judgment, in neuro-ophthalmology practice.

  17. [Apropos of preventive ophthalmologic interventions in the child population of compulsory school age. Authors' experience].

    Science.gov (United States)

    Cruciani, F; Mastromarino, A; Latini, M; Paganelli, G; Rocca, M; Fiore, F; Melino, G

    1993-05-01

    The results are reported of work carried out during the last five years by the Center of Social Ophthalmology, director Prof. G. Scuderi, which is part of the II Division of the Ophthalmologic Clinic of Rome University "La Sapienza" with the object of trying out together with territorial units a model of preventive intervention acting as a filter for specialized university facilities. In other words, already existing facilities and medical personnel were to be used and trained for specific methods and techniques. From 1985 through 1990, 787 children selected by ophthalmologic screening by school doctors among the compulsory school population of the RM 3 and 5 districts were seen and submitted to periodic checks. This cohort included children aged 5 to 14 without significant differences in sex distribution and with prevalence of the 8 to 10 year olds. Each subject was submitted to complete eye examination including refractometry and orthoptics, color vision, biomicroscopic and ophthalmoscopic examination. The principal findings show that about 36% of subjects examined have a natural vision of 11/10 while the high percentage of ametropia observed was mainly represented by astigmatism and hypermetropy, albeit of minor intensity. Strabismus was found in 2.79% and implied marked visual deficit that was often refractory to any type of treatment. In addition, the prevalence was determined of other abnormalities concerning eye motility, color vision and pathologies involving anterior segment and eyeground. In their conclusion, the authors stress the rarity of organic ocular pathology in children (mostly represented by inflammatory changes of the adnexes and conjunctiva) whereas amblyopia was one of the main causes of visual deficit in children. They stress the importance of early therapeutic intervention in order to allow complete visual rehabilitation. The results of the clinical model for prevention were excellent so that it can even be proposed for large scale

  18. Effectiveness of mobile-phone short message service (SMS reminders for ophthalmology outpatient appointments: Observational study

    Directory of Open Access Journals (Sweden)

    Car Josip

    2008-05-01

    Full Text Available Abstract Background Non-attendance for hospital outpatient appointments is a significant problem in many countries. It causes suboptimal use of clinical and administrative staff and financial losses, as well as longer waiting times. The use of Short Message Service (SMS appointment reminders potentially offers a cost-effective and time-efficient strategy to decrease non-attendance and so improve the efficiency of outpatient healthcare delivery. Methods An SMS text message was sent to patients with scheduled appointments between April and September 2006 in a hospital ophthalmology department in London, reminding them of their appointments. This group acted as the intervention group. Controls were patients with scheduled ophthalmology appointments who did not receive an SMS or any alternative reminder. Results During the period of the study, 11.2% (50/447 of patients who received an SMS appointment reminder were non-attenders, compared to 18.1% (1720/9512 who did not receive an SMS reminder. Non-attendance rates were 38% lower in patients who received an SMS reminder than in patients who did not receive a reminder (RR of non-attendance = 0.62; 95% CI = 0.48 – 0.80. Conclusion The use of SMS reminders for ophthalmology outpatient appointments was associated with a reduction of 38% in the likelihood of patients not attending their appointments, compared to no appointment reminder. The use of SMS reminders may also be more cost-effective than traditional appointment reminders and require less labour. These findings should be confirmed with a more rigorous study design before a wider roll-out.

  19. Development of community based curriculum on ophthalmology for under graduate medical course in Bangladesh.

    Science.gov (United States)

    Khan, A K; Hussain, A Z M I

    2012-08-01

    The curriculum represents the expression of educational ideas in practice. Ophthalmic education is the corner stone to improve eye care globally. Curriculum needs continuous modification varying in different geographic locations. Though 90% of common conditions are either preventable or curable but emphasis on the common conditions is inadequate. This is a stepwise descriptive study aiming to develop a community based ophthalmology curriculum for undergraduate medical course in Bangladesh conducted during March 2007 to February 2008 at UniSA School of Public Health and Life Sciences, University of South Asia, Banani, Dhaka. Delphi technique, a modified qualitative method was used to accumulate data and reaching a consensus opinion for developing the curriculum. Study approach includes two iterative rounds and finally a workshop. Iteration of round-I was "What are the eye diseases with overall knowledge of their management one MBBS physician should acquire"; followed by a list of eye diseases and topics for expert opinion. The response was collated. Iteration round-II was "How much a MBBS student should have percentage of knowledge, attitude and skills on each topic while being taught". The response was collated and presented to panel of expert ophthalmologists for discussion and validation. In the round-I Delphi, 400 (62%) out to total 641 ophthalmologist were randomly selected dividing in categories (62% in each) of Professor-22, Associate Professor-12, Assistant Professor-26, Consultant-27, ophthalmologists working in NGO-56 and ophthalmologists in private sector-257. Sixty (15%) responded with opinion. In the round-II, 200 (31%) including 60 of round-I, selected randomly but proportionately as before. Forty five (22.5%) responded with opinion. Result collated. The results and opinion of respondents were presented at a workshop attended by 24 (80%), out of 30 invited expert ophthalmic specialists for discussion, criticism, opinion, addition, modification and

  20. The Persian legend of ophthalmology: Ali Asghar Khodadoust and his everlasting lines.

    Science.gov (United States)

    Sajjadi, Sepideh; Fesharaki, Hamid; Abtahi, Zahra-Alsadat; Murray, Richard T; Fereidan-Esfahani, Mahboobeh; Mazloumi, Mehdi; Abtahi, Seyed-Hossein

    2013-06-01

    This is a brief celebratory overview of the fruitful life and scientific endeavors of Professor Ali Asghar Khodadoust (b.1935), a world renowned ophthalmologist, Persian icon of modern ophthalmology and an international pioneer of eye research. The global reputation of Dr. Khodadoust is rooted in his extensive studies on corneal diseases and transplantation biology. As a result of his truly deserved world renown, several famous American ophthalmologists have recognized him as the world's best corneal graft surgeon. Due to his exceptionally impressive achievements in this field, a clinical finding has been named in his honor, the "Khodadoust rejection line", a sign indicative of a chronic focal transplant reaction.

  1. [Carl Gustav Carus (1789-1869) and his single ophthalmologic publication].

    Science.gov (United States)

    Jähne, M

    1990-01-01

    Carl Gustav Carus is the most important personality in medicine in Dresden in the first half of the 19th century. He is well known for his manifold activity as a doctor, scientist and philosopher as well as a landscape painter of the romantic period. His literary output is estimated at about 25,000 printed pages. There is just one paper which touches ophthalmology and teratology: in 1842, Carus described the monstrous head of a pig with cyclopia. The discussion follows an idealistic line with comparative anatomical studies in fauna and flora.

  2. Decision support systems and applications in ophthalmology: literature and commercial review focused on mobile apps.

    Science.gov (United States)

    de la Torre-Díez, Isabel; Martínez-Pérez, Borja; López-Coronado, Miguel; Díaz, Javier Rodríguez; López, Miguel Maldonado

    2015-01-01

    The growing importance that mobile devices have in daily life has also reached health care and medicine. This is making the paradigm of health care change and the concept of mHealth or mobile health more relevant, whose main essence is the apps. This new reality makes it possible for doctors who are not specialist to have easy access to all the information generated in different corners of the world, making them potential keepers of that knowledge. However, the new daily information exceeds the limits of the human intellect, making Decision Support Systems (DSS) necessary for helping doctors to diagnose diseases and also help them to decide the attitude that has to be taken towards these diagnoses. These could improve the health care in remote areas and developing countries. All of this is even more important in diseases that are more prevalent in primary care and that directly affect the people's quality of life, this is the case in ophthalmological problems where in first patient care a specialist in ophthalmology is not involved. The goal of this paper is to analyse the state of the art of DSS in Ophthalmology. Many of them focused on diseases affecting the eye's posterior pole. For achieving the main purpose of this research work, a literature review and commercial apps analysis will be done. The used databases and systems will be IEEE Xplore, Web of Science (WoS), Scopus, and PubMed. The search is limited to articles published from 2000 until now. Later, different Mobile Decision Support System (MDSS) in Ophthalmology will be analyzed in the virtual stores for Android and iOS. 37 articles were selected according their thematic (posterior pole, anterior pole, Electronic Health Records (EHRs), cloud, data mining, algorithms and structures for DSS, and other) from a total of 600 found in the above cited databases. Very few mobile apps were found in the different stores. It can be concluded that almost all existing mobile apps are focused on the eye's posterior

  3. Procedural aspects of the organization of the comprehensive European Board of Ophthalmology Diploma examination.

    Science.gov (United States)

    Mathysen, Danny G P; Ringens, Peter J; Midena, Edoardo; Klett, Artur; Sunaric-Mégevand, Gordana; Martinez-Costa, Rafael; Curtin, Denise; Tassignon, Marie-José; Aclimandos, Wagih; Creuzot-Garcher, Catherine; Grupcheva, Christina

    2016-01-01

    The comprehensive European Board of Ophthalmology Diploma (EBOD) examination is one of 38 European medical specialty examinations. This review aims at disclosing the specific procedures and content of the EBOD examination. It is a descriptive study summarizing the present organization of the EBOD examination. It is the 3rd largest European postgraduate medical assessment after anaesthesiology and cardiology. The master language is English for the Part 1 written test (knowledge test with 52 modified type X multiple-choice questions) (in the past the written test was also available in French and German). Ophthalmology training of minimum 4 years in a full or associated European Union of Medical Specialists (UEMS) member state is a prerequisite. Problem-solving skills are tested in the Part 2 oral assessment, which is a viva of 4 subjects conducted in English with support for native language whenever feasible. The comprehensive EBOD examination is one of the leading examinations organized by UEMS European Boards or Specialist Sections from the point of number of examinees, item banking, and item contents.

  4. Procedural aspects of the organization of the comprehensive European Board of Ophthalmology Diploma examination

    Directory of Open Access Journals (Sweden)

    Danny G.P. Mathysen

    2016-07-01

    Full Text Available The comprehensive European Board of Ophthalmology Diploma (EBOD examination is one of 38 European medical specialty examinations. This review aims at disclosing the specific procedures and content of the EBOD examination. It is a descriptive study summarizing the present organization of the EBOD examination. It is the 3rd largest European postgraduate medical assessment after anaesthesiology and cardiology. The master language is English for the Part 1 written test (knowledge test with 52 modified type X multiple-choice questions (in the past the written test was also available in French and German. Ophthalmology training of minimum 4 years in a full or associated European Union of Medical Specialists (UEMS member state is a prerequisite. Problem-solving skills are tested in the Part 2 oral assessment, which is a viva of 4 subjects conducted in English with support for native language whenever feasible. The comprehensive EBOD examination is one of the leading examinations organized by UEMS European Boards or Specialist Sections from the point of number of examinees, item banking, and item contents.

  5. Ophthalmology and vision science research. Part 1: Understanding and using journal impact factors and citation indices.

    Science.gov (United States)

    Cartwright, Victoria A; McGhee, Charles N J

    2005-10-01

    In an increasingly "publish or perish" clinical and academic environment, all clinicians and clinician-scientists involved in research must have a firm understanding of the measures commonly used to assess the quality of scientific journals and, by default, those extended to grade individual articles and authors. The publication of research is a vital part of clinical and experimental research, and citation analyses of research publications have increasingly been adopted as a means of assessing the apparent quality of journals and the research published therein. In the first of a series of articles for those embarking on ophthalmic and vision science research, this paper discusses the key features of citation analysis, concentrating on the 2004 Journal Citation Report figures for the field of ophthalmology that include 42 ophthalmology, vision science, physiological optics, and optometry journals. The Institute for Scientific Information (ISI) calculates a number of parameters including citation counts, Journal Impact Factor (JIF), Immediacy Index, and cited/citing half-life. This article discusses the methods of calculation and possible uses along with current controversies and potential abuses. The JIF and its relevance, potential bias, and limitations are discussed in depth as it has become the most widely used analysis of journal quality. The possible alternatives to ISI citation analysis are presented, and we conclude that citation analysis can be considered a reasonable measure of journal research quality only if used correctly.

  6. Stem Cell Ophthalmology Treatment Study (SCOTS) for retinal and optic nerve diseases:a preliminary report

    Institute of Scientific and Technical Information of China (English)

    Jeffrey N Weiss; Steven Levy; Alexis Malkin

    2015-01-01

    In this report, we present the results of a single patient with optic neuropathy treated within the Stem Cell Ophthalmology Treatment Study (SCOTS). SCOTS is an Institutional Review Board approved clinical trial and is the largest ophthalmology stem cell study registered at the National Institutes of Health to date-www.clinicaltrials.gov Identifier NCT 01920867. SCOTS utilizes autologous bone marrow-derived stem cells in the treatment of optic nerve and retinal diseases. Pre-and post-treatment comprehensive eye exams were independently performed at the Wilmer Eye Institute at the Johns Hopkins Hospital, USA. A 27 year old female patient had lost vision approximately 5 years prior to enrollment in SCOTS. Pre-treatment best-corrected visual acuity at the Wilmer Eye Institute was 20/800 Right Eye (OD) and 20/4,000 Left Eye (OS). Four months following treatment in SCOTS, the central visual acuity had improved to 20/100 OD and 20/40 OS.

  7. Electronic Referrals and Digital Imaging Systems in Ophthalmology: A Global Perspective.

    Science.gov (United States)

    Jeganathan, V Swetha E; Hall, H Nikki; Sanders, Roshini

    2017-01-01

    Ophthalmology departments face intensifying pressure to expedite sight-saving treatments and reduce the global burden of disease. The use of electronic communication systems, digital imaging, and redesigned service care models is imperative for addressing such demands. The recently developed Scottish Eyecare Integration Project involves an electronic referral system from community optometry to the hospital ophthalmology department using National Health Service (NHS) email with digital ophthalmic images attached, via a virtual private network connection. The benefits over the previous system include reduced waiting times, improved triage, e-diagnosis in 20% without the need for hospital attendance, and rapid electronic feedback to referrers. We draw on the experience of the Scottish Eyecare Integration Project and discuss the global applications of this and other advances in teleophthalmology. We focus particularly on the implications for management and screening of chronic disease, such as glaucoma and diabetic eye disease, and ophthalmic disease, such as retinopathy of prematurity where diagnosis is almost entirely and critically dependent on fundus appearance. Currently in Scotland, approximately 75% of all referrals are electronic from community to hospital. The Scottish Eyecare Integration Project is globally the first of its kind and unique in a national health service. Such speedy, safe, and efficient models of communication are geographically sensitive to service provision, especially in remote and rural regions. Along with advances in teleophthalmology, such systems promote the earlier detection of sight-threatening disease and safe follow-up of non-sight-threatening disease in the community.

  8. Ophthalmological findings in infants with microcephaly and presumable intra-uterus Zika virus infection

    Directory of Open Access Journals (Sweden)

    Camila V. Ventura

    2016-02-01

    Full Text Available ABSTRACT Purpose: In 2015, a twenty-fold increase in the prevalence of microcephaly in Brazil was reported, and the Ministry of Health associated this abnormal prevalence with the maternal-fetal Zika virus (ZIKV transmission. Methods: We assessed the ophthalmological findings of ten mothers and their infants that had been clinically diagnosed with ZIKV-related microcephaly and presented ocular abnormalities, born from May to December 2015. Results: Seven mothers (70.0% referred symptoms during pregnancy (malaise, rash and arthralgia, of which six (85.7% were in the first trimester. At the time of exam, no ophthalmological abnormalities were identified in the mothers and they did not report ocular symptoms during pregnancy. Serology was negative in all infants for Toxoplasmosis, Rubella, Cytomegalovirus, Syphilis and Human Immunodeficiency Viruses. Ocular findings included macular alterations (gross pigment mottling and/or chorioretinal atrophy in fifteen eyes (75.0%, and optic nerve abnormalities (hypoplasia with double-ring sign, pallor, and/or increased cup-to-disk ratio in nine eyes (45.0%. Conclusions: Patients presented normal anterior segment and important macular and optic nerve abnormalities. Further studies will assess the visual significance of these alterations.

  9. Stem Cell Ophthalmology Treatment Study (SCOTS for retinal and optic nerve diseases: a preliminary report

    Directory of Open Access Journals (Sweden)

    Jeffrey N Weiss

    2015-01-01

    Full Text Available In this report, we present the results of a single patient with optic neuropathy treated within the Stem Cell Ophthalmology Treatment Study (SCOTS. SCOTS is an Institutional Review Board approved clinical trial and is the largest ophthalmology stem cell study registered at the National Institutes of Health to date- www.clinicaltrials.gov Identifier NCT 01920867. SCOTS utilizes autologous bone marrow-derived stem cells in the treatment of optic nerve and retinal diseases. Pre- and post-treatment comprehensive eye exams were independently performed at the Wilmer Eye Institute at the Johns Hopkins Hospital, USA. A 27 year old female patient had lost vision approximately 5 years prior to enrollment in SCOTS. Pre-treatment best-corrected visual acuity at the Wilmer Eye Institute was 20/800 Right Eye (OD and 20/4,000 Left Eye (OS. Four months following treatment in SCOTS, the central visual acuity had improved to 20/100 OD and 20/40 OS.

  10. Unique identification code for medical fundus images using blood vessel pattern for tele-ophthalmology applications.

    Science.gov (United States)

    Singh, Anushikha; Dutta, Malay Kishore; Sharma, Dilip Kumar

    2016-10-01

    Identification of fundus images during transmission and storage in database for tele-ophthalmology applications is an important issue in modern era. The proposed work presents a novel accurate method for generation of unique identification code for identification of fundus images for tele-ophthalmology applications and storage in databases. Unlike existing methods of steganography and watermarking, this method does not tamper the medical image as nothing is embedded in this approach and there is no loss of medical information. Strategic combination of unique blood vessel pattern and patient ID is considered for generation of unique identification code for the digital fundus images. Segmented blood vessel pattern near the optic disc is strategically combined with patient ID for generation of a unique identification code for the image. The proposed method of medical image identification is tested on the publically available DRIVE and MESSIDOR database of fundus image and results are encouraging. Experimental results indicate the uniqueness of identification code and lossless recovery of patient identity from unique identification code for integrity verification of fundus images. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  11. Neuro-ophthalmologic evaluation, quality of life, and functional disability in patients with MS.

    Science.gov (United States)

    Garcia-Martin, Elena; Rodriguez-Mena, Diego; Herrero, Raquel; Almarcegui, Carmen; Dolz, Isabel; Martin, Jesus; Ara, Jose R; Larrosa, Jose M; Polo, Vicente; Fernández, Javier; Pablo, Luis E

    2013-07-02

    To evaluate correlations between longitudinal changes in neuro-ophthalmologic measures and quality of life (QOL) and disability in patients with multiple sclerosis (MS), using optical coherence tomography (OCT), visual evoked potentials (VEP), and visual field examination. Fifty-four patients with relapsing-remitting MS were enrolled in this study and underwent Multiple Sclerosis Quality of Life questionnaire (54 items) (MSQOL-54) and Expanded Disability Status Scale (EDSS) evaluation, as well as complete neuro-ophthalmologic examination including visual field testing and retinal nerve fiber layer (RNFL) measurements using Cirrus and Spectralis OCT and VEP. All patients were re-evaluated at 12, 24, and 36 months. Logistical regression was performed to analyze which measures, if any, could predict QOL. Overall, RNFL thickness results at the baseline evaluation were significantly different from those at 3 years (p ≤ 0.05), but there were no differences in functional measures (visual acuity, contrast sensitivity, color vision, visual field, and VEP). A reduced MSQOL-54 score was associated with an increase in EDSS score and a decrease in both functional and structural parameters. Patients with longer MS duration presented with a lower MSQOL-54 score (reduction in QOL). Patients with progressive axonal loss as seen in RNFL results had a lower QOL and more functional disability.

  12. Tele-ophthalmology screening for proliferative diabetic retinopathy in urban primary care offices: an economic analysis.

    Science.gov (United States)

    Brady, Christopher J; Villanti, Andrea C; Gupta, Omesh P; Graham, Mark G; Sergott, Robert C

    2014-01-01

    To determine whether tele-ophthalmology screening for proliferative diabetic retinopathy (PDR) can be cost-saving. Adults with diabetes presenting for routine medical care underwent non-mydriatic fundus photography with remote grading. Direct medical costs were estimated using the Medicare fee schedule in the base case, with Medicaid and commercial insurance rates used for low and high values, respectively. One-way and probabilistic sensitivity analyses were performed. Of 99 participants, at least mild retinopathy was found in 24 (24.2%). Urgent consultation was recommended for eight participants (8.1%) for possible vision-threatening diabetic retinopathy, including two participants (three eyes) with PDR. In the base case, screening saved $36 per patient. A Monte Carlo simulation indicated that screening saved a median of $48 per patient. A substantial burden of diabetic retinopathy was identified, most of which was undiagnosed. In a closed system, tele-ophthalmology screening for PDR is likely to be cost-saving across the range of scenarios explored. Copyright 2014, SLACK Incorporated.

  13. Tele-ophthalmology for Age-Related Macular Degeneration and Diabetic Retinopathy Screening: A Systematic Review and Meta-analysis.

    Science.gov (United States)

    Kawaguchi, Atsushi; Sharafeldin, Noha; Sundaram, Aishwarya; Campbell, Sandy; Tennant, Matthew; Rudnisky, Christopher; Weis, Ezekiel; Damji, Karim F

    2017-08-07

    To synthesize high-quality evidence to compare traditional in-person screening and tele-ophthalmology screening. Only randomized controlled trials (RCTs) were included in this systematic review and meta-analysis. The intervention of interest was any type of tele-ophthalmology, including screening of diseases using remote devices. Studies involved patients receiving care from any trained provider via tele-ophthalmology, compared with those receiving equivalent face-to-face care. A search was executed on the following databases: Medline, EMBASE, EBM Reviews, Global Health, EBSCO-CINAHL, SCOPUS, ProQuest Dissertations and Theses Global, OCLC Papers First, and Web of Science Core Collection. Six outcomes of care for age-related macular degeneration (AMD), diabetic retinopathy (DR), or glaucoma were measured and analyzed. Two hundred thirty-seven records were assessed at the full-text level; six RCTs fulfilled inclusion criteria and were included in this review. Four studies involved participants with diabetes mellitus, and two studies examined choroidal neovascularization in AMD. Only data of detection of disease and participation in the screening program were used for the meta-analysis. Tele-ophthalmology had a 14% higher odds to detect disease than traditional examination; however, the result was not statistically significant (n = 2,012, odds ratio: 1.14, 95% confidence interval (CI): 0.52-2.53, p = 0.74). Meta-analysis results show that odds of having DR screening in the tele-ophthalmology group was 13.15 (95% CI: 8.01-21.61; p < 0.001) compared to the traditional screening program. The current evidence suggests that tele-ophthalmology for DR and age-related macular degeneration is as effective as in-person examination and potentially increases patient participation in screening.

  14. Effects of short duration morning bright light in healthy elderly subjects. I: subjective feeling and ophthalmological examinations.

    Science.gov (United States)

    Fukuda, N; Kohsaka, M; Sasamoto, Y; Koyama, E; Kobayashi, R; Honma, H; Matsubara, H; Nakano, T; Sakakibara, S

    1998-04-01

    Seven aged subjects aged 61-78 years were exposed to 6000 lx bright light for 30 min during morning hours at their homes for 1 week. Visual analog scale was recorded before bedtime and after rising to assess subjective feelings. Ophthalmological examinations were made before and after light exposure, to exclude pre-existing ocular disorders and to detect ocular damage. Furthermore, ocular fatigue was self-evaluated immediately before and after exposure. Visual analog scale results indicated that alertness reduced significantly before bedtime. Ophthalmological abnormalities were not found after exposure. These findings suggest that short duration morning bright light exposure reduces night-time vigilance.

  15. Improving the effectiveness of service delivery in the public healthcare sector: the case of ophthalmology services in Malaysia.

    Science.gov (United States)

    Foo, Chee Yoong; Lim, Ka Keat; Sivasampu, Sheamini; Dahian, Kamilah Binti; Goh, Pik Pin

    2015-08-28

    Rising demand of ophthalmology care is increasingly straining Malaysia's public healthcare sector due to its limited human and financial resources. Improving the effectiveness of ophthalmology service delivery can promote national policy goals of population health improvement and system sustainability. This study examined the performance variation of public ophthalmology service in Malaysia, estimated the potential output gain and investigated several factors that might explain the differential performance. Data for 2011 and 2012 on 36 ophthalmology centres operating in the Ministry of Health hospitals were used in this analysis. We first consulted a panel of ophthalmology service managers to understand the production of ophthalmology services and to verify the production model. We then assessed the relative performance of these centres using Data Envelopment Analysis (DEA). Efficiency scores (ES) were decomposed into technical, scale, and congestion component. Potential increase in service output was estimated. Sensitivity analysis of model changes was performed and stability of the result was assessed using bootstrap approach. Second stage Tobit regression was conducted to determine if hospital type, availability of day services and population characteristics were related to the DEA scores. In 2011, 33% of the ophthalmology centres were found to have ES > 1 (mean ES = 1.10). Potential output gains were 10% (SE ± 2.92), 7.4% (SE ± 2.06), 6.9% (SE ± 1.97) if the centres could overcome their technical, scale and congestion inefficiencies. More centres moved to the performance frontier in 2012 (mean ES = 1.07), with lower potential output gain. The model used has good stability. Robustness checks show that the DEA correctly identified low performing centres. Being in state hospital was significantly associated with better performance. Using DEA to benchmarking service performance of ophthalmology care could provide insights for policy

  16. A case of overlapping of Sturge Weber syndrome-Klippel Trenaunay syndrome and ophthalmological findings

    Directory of Open Access Journals (Sweden)

    Ersin Aydın

    2016-12-01

    Full Text Available Sturge-Weber syndrome (SWS is a neurocutaneous syndrome characterized by facial port wine stains, vascular lesions in the ipsilateral brain and meninges, and glaucoma. Klippel-Trenaunay syndrome (KTS is a rare congenital malformation associated with cutaneous vascular malformation, bony or soft tissue hypertrophy and venous varicosities in the affected limb. Although some cases have been reported in the literature, an overlap between these two phakomatoses is extremely rare and they have systemic and ocular affects. Here, we present a case showing the properties of both SWS and KTS and having interesting ophthalmological findings. This case is presented to emphasize that eye related complications might also be seen in these syndromes.

  17. Evaluation of a simulation tool in ophthalmology: application in teaching funduscopy

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    Joice Elise Androwiki

    2015-02-01

    Full Text Available Purpose: The aim of this study was to evaluate the Eye Retinopathy Trainer® as a teaching tool for direct ophthalmoscopy examination by comparing it with the traditional method using volunteers. Methods: Fourth year medical students received training in direct ophthalmoscopy using a simulation tool and human volunteers. Ninety students were randomized into a Simulation Group or a Control Group by the inclusion or absence of the simulation model in classroom practice. Differences between the groups were analyzed using unpaired Student’s t-test. Results: The Simulation Group was superior to the Control Group, with 51.06% successful in performing fundus examination in both the anatomical model simulation and the human model in comparison with 21.15% in the Control Group. Conclusion: The Eye Retinopathy Trainer® appears to be an effective teaching tool for practice and improvement of ophthalmologic examination among fourth year medical students.

  18. Sensorimotor Characteristics of Neuro-Ophthalmology and Oculo-Plastics Patients.

    Science.gov (United States)

    Christoff, Alex

    2015-01-01

    Certified orthoptists are routinely required, as a standard component of outpatient care, to examine and identify the cause of double vision described by neuro-ophthalmology and oculo-plastics patients. Peer-reviewed articles in the strabismus literature describing the significance of this role of the orthoptists, especially in more complex cases of strabismus, do exist, but are outdated. The importance of creating a differential diagnosis in the understanding of the disease process is a well-recognized component of medical education and modern medicine. This work was a retrospective chart review and descriptive study of the most common clinical characteristics of adult neuro-ophthalmology and oculo-plastics patients seen over a 9-year period by an orthoptist in a large, urban academic institution in the United States. History and clinical data obtained included demographic information; whether the subjects were neuro-ophthalmology or oculo-plastic patients or both; chief complaint; past medical history and associated medical risk factors; past ocular history of strabismus or amblyopia; whether reported diplopia was monocular or binocular; visual acuities; sensorimotor examination and fusion status information; presence or absence of ptosis; pupil size and reactivity; basic accommodative function; orthoptist and physician diagnoses; and suggested treatment of diplopia. Five hundred seventy-five subjects were identified based on inclusion criteria. Racial demographics matched that of the state of Maryland, with the majority of the patients being Caucasian. The minority were of Hispanic origin. Ninety-one percent of the study cohort was referred by the department of neuro-ophthalmology at the institution. Hypertension was a statistically significant medical risk factor for acquired strabismus and diplopia in this adult cohort. Etiology for the strabismus and associated diplopia suggested by the orthoptist was in close agreement with the final diagnosis made by the

  19. Correlation between weather and incidence of selected ophthalmological diagnoses: a database analysis

    Science.gov (United States)

    Kern, Christoph; Kortüm, Karsten; Müller, Michael; Raabe, Florian; Mayer, Wolfgang Johann; Priglinger, Siegfried; Kreutzer, Thomas Christian

    2016-01-01

    Purpose Our aim was to correlate the overall patient volume and the incidence of several ophthalmological diseases in our emergency department with weather data. Patients and methods For data analysis, we used our clinical data warehouse and weather data. We investigated the weekly overall patient volume and the average weekly incidence of all encoded diagnoses of “conjunctivitis”, “foreign body”, “acute iridocyclitis”, and “corneal abrasion”. A Spearman’s correlation was performed to link these data with the weekly average sunshine duration, temperature, and wind speed. Results We noticed increased patient volume in correlation with increasing sunshine duration and higher temperature. Moreover, we found a positive correlation between the weekly incidences of conjunctivitis and of foreign body and weather data. Conclusion The results of this data analysis reveal the possible influence of external conditions on the health of a population and can be used for weather-dependent resource allocation. PMID:27601872

  20. A rare case of puberty onset congenital erythropoietic porphyria with ophthalmological manifestations

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    Debjani Mishra

    2016-01-01

    Full Text Available A 27-year-old male patient was presented with foreign body sensation in both the eyes for 2 years duration and blisters followed by scarring and pigmentation in the photo-exposed areas of the body over the previous 12 years. His urine was reddish colored for the previous year. On examination, there was scarring, hyper-pigmentation of photo-exposed parts of the body along with resorption of the distal phalanges of fingers in both hands except the smallest digit which had onycholysis. Ocular examination indicated scleral necrosis in the interpalpebral areas in both eyes and bilateral dry eye. Hematological examination indicated a picture suggestive of hemolytic anemia. Abdominal ultrasonography indicated an enlarged spleen. These clinical features are suggestive of puberty onset congenital erythropoietic porphyria with ophthalmological manifestations.

  1. [Electronic patient records and teleophthalmology. Part 2: concrete projects in ophthalmology].

    Science.gov (United States)

    Schargus, M; Michelson, G; Grehn, F

    2011-07-01

    Electronic storage of patient-related data will replace paper-based patient records in the near future. Because of the high visualization needed in ophthalmology integrated electronic data storage and usage will be very useful. Chronic diseases like glaucoma, macular degeneration and diabetic retinopathy would benefit from long-term data storage and analysis. Unfortunately there are nearly no widely accepted systems available providing these options. Another important point is the simplification of existing diagnostic procedures and nomenclature on an international level. Increasing mobility of patients requires a better portability of existing medical examination data between different physicians. This is the only way to provide continuously high levels of quality in patient care and to simultaneously reduce costs and prevent unnecessary secondary examinations.

  2. Ophthalmological affectation: A way to mask Miastenia Gravis. A case purpose.

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    Néstor R. Sánchez Dacal

    2012-06-01

    Full Text Available Myasthenia Gravis MG is an autoimmune and chronic neuromuscular disease characterized by variable of weakness in the skeletal muscles that control the eye movements and it is confused with an ophthalmological disorder. With this presentation we pretend to systematize the Theoretical references about MG which allow making a correct diagnosis of the disease from the experience of a clinical case. The theory about MG regarding the presentation of the disease is discussed, emphasising on the significance of its differential diagnosis with an ophthalmopathy, which will contribute to apply a proper treatment and a satisfactory evolution of the patient, arriving to the conclusion that affectation of the III cranial pair is a way of frequent presentation of MG, being valuable the differential diagnosis of the ophthalmopaties in these entities.

  3. Re-engineering the Resident Applicant Selection Process in Ophthalmology: A Literature Review and Recommendations for Improvement

    NARCIS (Netherlands)

    Lee, Andrew G.; Golnik, Karl C.; Oetting, Thomas A.; Beaver, Hilary A.; Boldt, H. Culver; Olson, Richard; Greenlee, Emily; Abramoff, M.D.; Johnson, A. Tim; Carter, Keith

    2008-01-01

    The current resident selection process for ophthalmology has undergone little change over the last several years and remains highly dependent on the traditional selection factors (i.e., grades, honors, letters of recommendation, and an interview). Unfortunately, these selection factors have not been

  4. Author reply: Steven A. Nissman - Electronic Health Records (Ophthalmology, Volume 116, Issue 5, May 2009, Pages 1018-1019)

    NARCIS (Netherlands)

    Chiang, Michael F.; Boland, Michael V.; Margolis, James W.; Lum, Flora; Abramoff, M.D.; Hildebrand, P. Lloyd

    2009-01-01

    We respect the thoughtfulness that Dr. Nissman invested into his decision-making process, and completely agree with his observation that implementation of electronic health record (EHR) systems may present difficulties for small ophthalmology practices. The low rate of EHR adoption in our survey and

  5. An Interactive Method for Teaching Anatomy of the Human Eye for Medical Students in Ophthalmology Clinical Rotations

    Science.gov (United States)

    Kivell, Tracy L.; Doyle, Sara K.; Madden, Richard H.; Mitchell, Terry L.; Sims, Ershela L.

    2009-01-01

    Much research has shown the benefits of additional anatomical learning and dissection beyond the first year of medical school human gross anatomy, all the way through postgraduate medical training. We have developed an interactive method for teaching eye and orbit anatomy to medical students in their ophthalmology rotation at Duke University…

  6. Ophthalmology residency training in Jordan: an evaluation of quality and comparison with international standards

    Institute of Scientific and Technical Information of China (English)

    Khalil; M.Al-Salem; Fawwaz; A.Al-Sarayra; Mohammad; Abu; Al-Dabaat; Wisam; Shihadeh; Mohammad; M.Al-Salem; Mahmoud; K.Al-Salem; Shlomit; Schaal

    2014-01-01

    AIM:To evaluate Jordanian ophthalmology residency programs in achieving competencies outlined by the International Council of Ophthalmology(ICO) and residents’ satisfaction with available training programs in Jordan, and to highlight weakness points that may be improved and strengthened.· METHODS:A closed-ended questionnaire was circulated to all ophthalmologists who completed their training in Jordanian institutions between 2006 and 2011,to measure the quality of residency training and satisfaction level with regards to clinical conferences,journal clubs, scientific lectures, wet lab sessions,simulations, outpatient clinics and operating room training. Barriers to a successful board exam were cited.All ophthalmologists had official residency training in Jordanian Hospitals; this includes military, university,governmental and private sector hospitals.RESULTS:Sixty-one questionnaires completed out of69 circulated. Males(75.4%) were more than females.Mean age was 32.5±3.27 y. A total 21(34.4%) responders expressed an overall satisfaction, 38(62.3%) were dissatisfied and 2(3.3%) were equivocal. Respondents reported insufficient exposure to low-vision rehabilitation57(93.4%),or refraction and glasses prescription 34(55.7%).Regarding operative experiences, the mean cataract extraction per-resident was 43 cataracts; the number of phacoemulsification surgery was 2.96 per-resident, 46(75.4%)of responders never did a single phacoemulsificationduring residency. Nine(14.8%) had training in refractive surgery, and 15(24.6%) assisted orbital surgery. Fortyfour(72.1%) never assisted in vitreoretinal surgery.Among The graduates surveyed, 14(23.0%) passed Jordanian licensing board exam at the first attempt, and felt that their residency programs adequately prepared them for the examinations.· CONCLUSION:Around two thirds(62.3%) of ophthalmologists expressed dissatisfaction with residency training at Jordanian programs, further study is required to assess each program

  7. Using Electronic Health Records to Build an Ophthalmologic Data Warehouse and Visualize Patients' Data.

    Science.gov (United States)

    Kortüm, Karsten U; Müller, Michael; Kern, Christoph; Babenko, Alexander; Mayer, Wolfgang J; Kampik, Anselm; Kreutzer, Thomas C; Priglinger, Siegfried; Hirneiss, Christoph

    2017-06-01

    To develop a near-real-time data warehouse (DW) in an academic ophthalmologic center to gain scientific use of increasing digital data from electronic medical records (EMR) and diagnostic devices. Database development. Specific macular clinic user interfaces within the institutional hospital information system were created. Orders for imaging modalities were sent by an EMR-linked picture-archiving and communications system to the respective devices. All data of 325 767 patients since 2002 were gathered in a DW running on an SQL database. A data discovery tool was developed. An exemplary search for patients with age-related macular degeneration, performed cataract surgery, and at least 10 intravitreal (excluding bevacizumab) injections was conducted. Data related to those patients (3 142 204 diagnoses [including diagnoses from other fields of medicine], 720 721 procedures [eg, surgery], and 45 416 intravitreal injections) were stored, including 81 274 optical coherence tomography measurements. A web-based browsing tool was successfully developed for data visualization and filtering data by several linked criteria, for example, minimum number of intravitreal injections of a specific drug and visual acuity interval. The exemplary search identified 450 patients with 516 eyes meeting all criteria. A DW was successfully implemented in an ophthalmologic academic environment to support and facilitate research by using increasing EMR and measurement data. The identification of eligible patients for studies was simplified. In future, software for decision support can be developed based on the DW and its structured data. The improved classification of diseases and semiautomatic validation of data via machine learning are warranted. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. The Impact of the Economy and Recessions on the Marketplace Demand for Ophthalmologists (An American Ophthalmological Society Thesis)

    Science.gov (United States)

    Adelman, Ron A.; Nwanze, Chukwuemeka C.

    2011-01-01

    Purpose To develop a help-wanted index (HWI) to measure trends in marketplace demand for ophthalmologists, to identify the economic drivers of demand, and to determine the impact of economic recessions on the ophthalmology job market. Methods Review of physician recruitment advertisements appearing in the journals Ophthalmology, American Journal of Ophthalmology, and Archives of Ophthalmology from January 1980 through June 2006. Results Over the 26-year study period a consistent increase in the demand for subspecialists (31% of HWI in 1980 to 80% in 2005) was noted. There was also an increase in the demand for academic ophthalmologists. The need for academic ophthalmologists seems to be correlated with national research expenditure and stock market gains (P = .00191), whereas demand for private practice ophthalmologists seems to be correlated with the national economic well-being, as measured by gross domestic product (GDP) (P < .001). Residency applicants (P = .0128) and fellowship applicants (P = .0198) respond to marketplace demand. During the recessions, the demand for ophthalmologists fell 2 to 3 years after the economic downturn. Conclusions Over a 26-year period, HWI data suggest an increased need for subspecialists and academic ophthalmologists. The ophthalmic community has been quick to respond to marketplace demand. National research expenditure, stock market gains, GDP, and discretionary health care expenditure have been associated with the ophthalmology job market. These factors tend to decline with economic recessions. Historically, the demand for ophthalmologists has declined 2 to 3 years following a recession, which may mean lower demand in the near future, given the recent recession. PMID:22253483

  9. Can children undergoing ophthalmologic examinations under anesthesia be safely anesthetized without using an IV line?

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    Vigoda M

    2011-04-01

    Full Text Available Michael M Vigoda, Azeema Latiff, Timothy G Murray, Jacqueline L Tutiven, Audina M Berrocal, Steven GayerBascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USAPurpose: To document that with proper patient and procedure selection, children undergoing general inhalational anesthesia for ophthalmologic exams (with or without photos, ultrasound, laser treatment, peri-ocular injection of chemotherapy, suture removal, and/or replacement of ocular prosthesis can be safely anesthetized without the use of an intravenous (IV line. Children are rarely anesthetized without IV access placement. We performed a retrospective study to determine our incidence of IV access placement during examinations under anesthesia (EUA and the incidence of adverse events that required intraoperative IV access placement.Methods: Data collected from our operating room (OR information system includes but is not limited to diagnosis, anesthesiologist, surgeon, and location of IV catheter (if applicable, patient’s date of birth, actual procedure, and anesthesia/procedure times. We reviewed the OR and anesthetic records of children (>1 month and <10 years who underwent EUAs between January 1, 2003 and May 31, 2009. We determined the percentage of children who were anesthetized without IV access placement, as well as the incidence of any adverse events that required IV access placement, intraoperatively.Results: We analyzed data from 3196 procedures performed during a 77-month period. Patients’ ages ranged from 1 month to 9 years. Overall, 92% of procedures were performed without IV access placement. Procedure duration ranged from 1–39 minutes. Reasons for IV access placement included parental preference for antinausea medication and/or attending preference for IV access placement. No child who underwent anesthesia without an IV line had an intraoperative adverse event requiring insertion of an IV line.Conclusion: Our data suggest that for

  10. [Role and place of ophthalmological methods in the diagnosis of lesions of the main vessels of the brain].

    Science.gov (United States)

    Bishele, N A; Nesterov, A P; Lavrent'ev, A V; Abramov, I S

    1998-01-01

    The study was aimed at detecting changes in visual functions and organ of vision in patients with involvement of the main vessels of the head and injuries to this vessels in patients with expressed ischemic diseases of the organ of vision. Twenty-four patients with occlusive disorders of the carotid arteries and 22 with retinal and ocular nerve diseases with the ischemic component were examined. The share of carotid artery abnormalities in the second group was 27.3%. Total efficacy of ophthalmological methods of diagnosis in the group with carotid artery involvement was 89.4%, this demonstrating high efficacy of ophthalmological methods for the diagnosis of involvement of the main cerebral vessels. Static quantitative perimetry proved to be the most effective method. It permits reliable detection of the slightest changes and assess the efficacy of surgical treatment.

  11. Giant cell arteritis in a neuro-ophthalmology clinic in Saskatoon, 1998-2003.

    Science.gov (United States)

    Ramstead, Cory L; Patel, Anil D

    2007-04-01

    We present a retrospective review of all biopsy-positive cases of giant cell arteritis (GCA) presenting to a neuro-ophthalmology practice in Saskatoon, Saskatchewan. Records of 141 consecutive patients who underwent temporal artery biopsy at the Saskatoon Eye Centre from July 1998 through June 2003 were reviewed. Patients that were biopsy-positive for GCA were studied and an estimated regional incidence was calculated. Study variables included age at diagnosis, sex, ethnicity, erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) level. Of 141 patients, 37 (26%) had a positive biopsy result for GCA; 11 underwent a second biopsy for a total of 152 biopsies. The average age of the biopsy-positive patients was 76.5 (SD 8.2) years, and the female-to-male ratio was 2.4:l. There were 35 patients (95%) of European descent and 2 patients (5%) of Aboriginal descent. Twenty-three patients had both ESR and CRP testing done before starting steroids. The ESR was elevated in 19 (83%) and the CRP in 22 (96%). The estimated incidence of GCA for Saskatoon and area was 9.4 per 100,000 for people over the age of 50 years. GCA occurs primarily in people of European descent; however, it can affect North American people of Aboriginal descent. Sensitivity for the detection of GCA is higher in CRP than in ESR. The estimated incidence of GCA in Saskatoon and surrounding referral area is moderate compared with other northern areas.

  12. Trends in ophthalmology journals: a five-year bibliometric analysis (2009-2013).

    Science.gov (United States)

    Schulz, Christopher B; Kennedy, Alasdair; Rymer, Ben C

    2016-01-01

    To explore the trends in the ophthalmic literature over a 5-year period in relation to country, research expenditure and demographics. Articles published between 2009 and 2013 by the 20highest-contributing countries in the 20 top-ranked ophthalmology journals were identified by their country of affiliation. The number of articles published and mean impact factor were measured per country for each year and trends explored using regression analysis with 5-year and 10-year forecasts calculated. Data on research expenditure was collected and tested for correlation with the number of articles and mean impact factor. The analysis included 19 338 articles. The USA, UK and Europe accounted for 60.2% of articles published, with the USA contributing 7388 articles (34.0%). The USA also demonstrated the highest mean impact factor (3.5). Research expenditure was significantly correlated with both research output (r=0.86, PEuropean countries are major contributors of ophthalmic research, the productivity of some Asian countries is growing impressively. The contribution of China, Korea and India is forecasted to outweigh that of Europe by 2023. Research expenditure is highly correlated with research productivity and these trends reflect the differing economic priorities across the world.

  13. The international council of ophthalmology: vision for ophthalmic education in an interdependent world.

    Science.gov (United States)

    Lee, Andrew G; Golnik, Karl C; Tso, Mark O M; Spivey, Bruce; Miller, Kathleen; Gauthier, Tina-Marie

    2012-10-01

    To describe the emerging strategic global perspective of the International Council of Ophthalmology (ICO) efforts in ophthalmic education. A global perspective describing how the development of sophisticated educational tools in tandem with information technology can revolutionize ophthalmic education worldwide. Review of ICO educational tools, resources, and programs that are available to ophthalmic educators across the globe. With the explosive growth of the Internet, the ability to access medical information in the most isolated of locations is now possible. Through specific ICO initiatives, including the ICO curricula, the "Teaching the Teachers" program, and the launching of the new ICO Center for Ophthalmic Educators, the ICO is providing ophthalmic educators across the globe with access to standardized but customizable educational programs and tools to better train ophthalmologists and allied eye care professionals throughout the world. Access to educational tools and strengthening of global learning will help providers meet the goals of VISION 2020 and beyond in eliminating avoidable blindness. It is the intent of the ICO that its programs for ophthalmic educators, including conferences, courses, curricula, and online resources, result in better-trained ophthalmologists and eye care professionals worldwide. Copyright © 2012 Elsevier Inc. All rights reserved.

  14. Guiding role of typical cases in clinical training for ophthalmology professional degree graduate students

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    Zhe Wang

    2014-05-01

    Full Text Available With the change of the concept of graduate enrollment, the recruiting proportion of clinical medicine professional degree graduate students is more and more, and the training of professional degree graduate students is increasingly focusing on practical. In our experience in clinical training for ophthalmology professional degree graduate students, increasing the ward clinical practice time is important. For particular emphasis on the guiding role of the typical cases, each professional group combined their professional characteristics of the typical cases to instruct the graduate students, training their clinical diagnosis and treatment ability, training their microsurgical techniques. From clinical medical writing, record summary, literature review, professional degree graduate students could expand their knowledge structure, practice their thesis writing ability. Based on the typical cases, expansion of knowledge coverage, they could improve the ability of diagnosis and treatment for special disease cases. In this rigorous training system, professional degree graduate students can learn by analogy, and focus on typical cases to get the most intuitive panoramic understanding of the diseases, with a minimum of time to master the most clinical knowledge, to enrich clinical experience, and to lay the foundation for future work in the assessment.

  15. Correlation between weather and incidence of selected ophthalmological diagnoses: a database analysis

    Directory of Open Access Journals (Sweden)

    Kern C

    2016-08-01

    Full Text Available Christoph Kern, Karsten Kortüm, Michael Müller, Florian Raabe, Wolfgang Johann Mayer, Siegfried Priglinger, Thomas Christian Kreutzer University Eye Hospital Munich, Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich, Germany Purpose: Our aim was to correlate the overall patient volume and the incidence of several ophthalmological diseases in our emergency department with weather data. Patients and methods: For data analysis, we used our clinical data warehouse and weather data. We investigated the weekly overall patient volume and the average weekly incidence of all encoded diagnoses of “conjunctivitis”, “foreign body”, “acute iridocyclitis”, and “corneal abrasion”. A Spearman’s correlation was performed to link these data with the weekly average sunshine duration, temperature, and wind speed. Results: We noticed increased patient volume in correlation with increasing sunshine duration and higher temperature. Moreover, we found a positive correlation between the weekly incidences of conjunctivitis and of foreign body and weather data. Conclusion: The results of this data analysis reveal the possible influence of external conditions on the health of a population and can be used for weather-dependent resource allocation. Keywords: corneal injury, trauma, uveitis, conjunctivitis, weather

  16. Interventions for toxoplasma retinochoroiditis: a report by the American Academy of Ophthalmology.

    Science.gov (United States)

    Kim, Stephen J; Scott, Ingrid U; Brown, Gary C; Brown, Melissa M; Ho, Allen C; Ip, Michael S; Recchia, Franco M

    2013-02-01

    To evaluate the available evidence in peer-reviewed publications about the outcomes and safety of interventions for toxoplasma retinochoroiditis (TRC). Literature searches of the PubMed and the Cochrane Library databases were conducted last on July 20, 2011, with no date restrictions. The searches retrieved 275 unique citations, and 36 articles of possible clinical relevance were selected for full text review. Of these 36 articles, 11 were deemed sufficiently relevant or of interest, and they were rated according to strength of evidence. Eight of the 11 studies reviewed were randomized controlled studies, and none of them demonstrated that routine antibiotic or corticosteroid treatment of TRC favorably affects visual outcomes or reduces lesion size. There is level II evidence from 1 study suggesting that long-term treatment with combined trimethoprim and sulfamethoxazole prevented recurrent disease in patients with chronic relapsing TRC. Adverse effects of antibiotic treatment were reported in as many as 25% of patients. There was no evidence supporting the efficacy of other nonmedical treatments such as laser photocoagulation. There is a lack of level I evidence to support the efficacy of routine antibiotic or corticosteroid treatment for acute TRC in immunocompetent patients. There is level II evidence suggesting that long-term prophylactic treatment may reduce recurrences in chronic relapsing TRC. Adverse effects of certain antibiotic regimens are frequent, and patients require regular monitoring and timely discontinuation of the antibiotic in some cases. Copyright © 2013 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  17. Sir Charles Bell (1774-1842): contributions to neuro-ophthalmology.

    Science.gov (United States)

    Grzybowski, Andrzej; Kaufman, Matthew H

    2007-12-01

    Sir Charles Bell (1774-1842) was a Scottish anatomist, physiologist, neurologist, artist and surgeon, who enjoyed a distinguished career in teaching and clinical practice in London between 1804 and 1836. In 1814, he was appointed to the surgical staff of the Middlesex Hospital. In 1824, he was elected Professor of Anatomy and Surgery at the Royal College of Surgeons of England, and shortly afterwards was elected Professor of Physiology at the University of London. In 1831, he was knighted on the accession of William IV. In 1836, he was elected to the Chair of Surgery in the University of Edinburgh, and remained there until his death in 1842, at 68 years of age. During his career, Bell was a prolific medical author, a brilliant medical researcher and a skilled artist. In 1811, he discovered the distinct functions of the motor and sensory nerves, findings that were initially published in a pamphlet entitled 'Ideas of a New Anatomy of the Brain'. In 1821, Bell described the long thoracic nerve, which supplies the serratus anterior muscle, and which now bears his name. In the same paper he showed that lesions of the seventh cranial nerve produce facial paralysis (now termed Bell's palsy). He also demonstrated that the fifth cranial nerve is of sensory importance to the face and controls the muscles of mastication, whereas the seventh cranial nerve principally controls the muscles of facial expression. Bell published research on a number of ophthalmological subjects. This paper reviews some of these latter achievements.

  18. Drug Utilization Study in Outpatient Ophthalmology Department of Government Medical College Jammu

    Directory of Open Access Journals (Sweden)

    Meenakshi Nehru, K. Kohli, B. Kapoor, P. Sadhotra, V. Chopra, R. Sharma

    2005-07-01

    Full Text Available The present study was undertaken to assess the patterns of prescription and drug utilization bymeasuring WHO delineated drug use indicators. This study was conducted in the PostgraduateDepartment of Pharmacology and Therapeutics in collaboration with the Postgraduate Departmentof Ophthalmology Govt. Medical College Hospital, Jammu. Total number of prescriptions analyzedwere 440 , in which total of 822 drugs were prescribed. Analysis of the prescriptions showed thataverage number of drugs per prescription was 1.87. The maximum number of drugs prescribed werein the form of eye drops (66.18%, followed by ointments (16%, capsules (9.5%, tablet (6.57%,syrup (0.73%, injection (0.73% and lotion (0.24%. The dosage form was indicated for 94%,frequency of drug administration for 98% drugs and duration of treatment for only 75% of the drugsprescribed. The number of antibiotics prescribed was 266 (32.26%, out of these 160 (60.15%antibiotics prescribed in the form of drops, 100 (37.59% as ointment and 6 (2.26% orally. Numberof encounters with anti-inflammatory and antiallergic drugs was 92 (11.2%, mydriatics and cycloplegics64(7.9%, miotics 20 (2.4%, multivitamins 58 (7.05% andothers used were lubricant and miscellaneouseye drops 322 (40%. Common prescription writing errors were minimum and there was no evidence ofpolypharmacy. However, duration of treatment and prescribing by generic name was very low.

  19. Pediatric ophthalmology and childhood reading difficulties: Overview of reading development and assessments for the pediatric ophthalmologist.

    Science.gov (United States)

    Collins, Megan E; Mudie, Lucy I; Inns, Amanda J; Repka, Michael X

    2017-09-04

    Reading difficulties are common in the pediatric population, and large socioeconomic disparities exist. In the United States 46% of white children achieved expected reading proficiency by the end of fourth grade, while only 21% of Hispanic and 18% of African American children were reading at the expected level. Reading is an involved cognitive process with many subskills; likewise, development of reading proficiency is a complex and continuous process. Failure to achieve reading proficiency or even early difficulty with reading can affect a child's academic performance for years to come. Some studies suggest reading proficiency may be related to later success in life. Although many problems with reading are not related to vision, a vision assessment is recommended for children with reading difficulties and a suspected vision problem. The process of reading development as well as the varied educational assessments of reading are presented here for pediatric ophthalmologists. Copyright © 2017 American Association for Pediatric Ophthalmology and Strabismus. Published by Elsevier Inc. All rights reserved.

  20. Magnetic resonance imaging diagnosis of the locus of lesions in neuro-ophthalmological diseases

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    Nobuto, Keiko; Oka, Tomomi; Ishiguro, Mami; Ohnishi, Tohru; Fukushima, Masahiro; Tsutsui, Jun (Kawasaki Medical School, Kurashiki, Okayama (Japan))

    1989-12-01

    Seven patients with neuro-opthalmological diseases were examined by X-ray computed tomography (CT) and magnetic resonance imaging (MRI), and the application of the latter in these diseases was studied. The cases included one each of rhinogenous optic neuropathy with mucocele in the ethnoid sinus, pituitary adenoma, multiple sclerosis, multiple cerebral infarction, hemangioma in the pontine region, one-and-a-half syndrome, and oculomotor nerve palsy with midbrain infarction. We were able to diagnose the pituitary adenoma and the multiple cerebral infarction by both MRI and CT, but in the other cases the lesions could not be detected by CT and some smaller lesions were visualized by MRI alone. These smaller lesions were in the paranasal sinus and brain stem, where CT diagnosis is difficult because of bone artifacts. The absence of bone artifacts was one of the advantages of MRI as evaluated in this study. Poor demonstration of calcification and bones, however, seemed to be a weak point. Our study showed MRI to be effective in examining neuro-ophthalmological diseases. (author).

  1. Ophthalmologic wax models as an educational tool for 18th-century vision scientists.

    Science.gov (United States)

    Zampieri, Fabio; Comacchio, Francesco; Zanatta, Alberto

    2017-02-16

    The Medical Faculties of the University of Padua (Italy) and the University of Vienna (Austria) preserved two series of wax models, made by the Austrian Johann Nepomuk Hoffmayr at the beginning of the 19th century. These models were created in a period of evolution of both medical specialties and organ pathology, which brought morbid organs at the centre of medical investigation. Ceroplastic was considered a useful tool for didactic and research, as it provided a three-dimensional realistically coloured reproduction of organic lesions. The models represent the typical eye diseases of the period, in particular those affecting external parts, which could be investigated without the need for specific instruments devised for the observation of the inner and posterior anatomy of the eye, at that time not yet available. Even if the nosological categories then employed by Hoffmayr were different from those currently used, it has been possible to find a correspondence thanks to the ophthalmological literature of his period. Ceroplastic started to decline at the end of 19th century, substituted by the much less expensive method of preservation of morbid organs in formalin and by new techniques of investigation of the inner body, such as X-ray. © 2017 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

  2. [Orbital Adipose Tissue: Just a Fat Pad or Terra Incognita in Ophthalmology].

    Science.gov (United States)

    Borzenok, S A; Afanasyeva, D S; Gushchina, M B

    2015-01-01

    Our understanding of the role of adipose tissue has been completely changed during the past decades. The knowledge of its contribution to endocrine and immune pathways opened the new insights on the pathogenesis and therapy of many diseases and new perspectives for the regenerative medicine. The further researches should be provided to study anatomy and functions of local fat depots in more details. Of the most interest is the orbital adipose tissue due to its origin from the neural crest. This review represents the current data about anatomy, structure, cell composition and biochemistry of orbital fat. The main attention is put to such cell types as adipocytes and adipose derived mesenchymal stem cells. The foreign authors' findings on such characteristics of stem cells from orbital adipose tissue as CD markers and differential capacity are reviewed. The found evidences of interaction between orbital adipose tissue, eyeball and associated structures allow us to hypothesize that this fat depot may contribute to various ocular pathology. In this paper, we outlined the possible directions for further investigation and clinical application of orbital fat and cells its composing in ophthalmology, reconstructive and plastic surgery and regenerative medicine.

  3. [Ophthalmologic reading charts : Part 2: Current logarithmically scaled reading charts].

    Science.gov (United States)

    Radner, W

    2016-12-01

    To analyze currently available reading charts regarding print size, logarithmic print size progression, and the background of test-item standardization. For the present study, the following logarithmically scaled reading charts were investigated using a measuring microscope (iNexis VMA 2520; Nikon, Tokyo): Eschenbach, Zeiss, OCULUS, MNREAD (Minnesota Near Reading Test), Colenbrander, and RADNER. Calculations were made according to EN-ISO 8596 and the International Research Council recommendations. Modern reading charts and cards exhibit a logarithmic progression of print sizes. The RADNER reading charts comprise four different cards with standardized test items (sentence optotypes), a well-defined stop criterion, accurate letter sizes, and a high print quality. Numbers and Landolt rings are also given in the booklet. The OCULUS cards have currently been reissued according to recent standards and also exhibit a high print quality. In addition to letters, numbers, Landolt rings, and examples taken from a timetable and the telephone book, sheet music is also offered. The Colenbrander cards use short sentences of 44 characters, including spaces, and exhibit inaccuracy at smaller letter sizes, as do the MNREAD cards. The MNREAD cards use sentences of 60 characters, including spaces, and have a high print quality. Modern reading charts show that international standards can be achieved with test items similar to optotypes, by using recent technology and developing new concepts of test-item standardization. Accurate print sizes, high print quality, and a logarithmic progression should become the minimum requirements for reading charts and reading cards in ophthalmology.

  4. Indications for and techniques of keratoplasty at Vietnam National Institute of Ophthalmology

    Directory of Open Access Journals (Sweden)

    Pham Ngoc Dong

    2016-03-01

    Full Text Available AIM: To report the indications for and techniques of corneal transplantation at Vietnam National Institute of Ophthalmology (VNIO over a period of 12y (2002-2013. METHODS: Records of patients who had undergone corneal transplantation at VNIO from January 1, 2002 to January 1, 2014 were reviewed to determine the indication for and type of corneal transplant performed. Patient age, gender, indication for corneal transplantation and surgical technique were recorded and analyzed. RESULTS: Corneal transplantation were underwent in 1390 eyes of 1278 patients with a mean age of 44.9±18.1y during the period under review. The most common indication was infectious corneal ulcer (n=670; 48.2%, followed by corneal scar (n=333, 24.0%, corneal dystrophy (n=138, 9.9% and failed graft (n=112, 8.1%. Nearly all procedures performed were penetrating keratoplasty (n=1300, 93.5%, with a few lamellar keratoplasty procedures performed: lamellar keratoplasty (n=52, 3.7%, Descemet’s stripping automated endothelial keratoplasty (n=27, 1.9% and deep anterior lamellar keratoplasty (n=11, 0.8%. CONCLUSION: While the most common indication for keratoplasty was infectious keratitis, nearly all indications for corneal transplantation were managed with penetrating keratoplasty. However, lamellar keratoplasty techniques, including deep anterior lamellar keratoplasty and Descemet’s stripping automated endothelial keratoplasty, are being performed with increasing frequency for isolated stromal and endothelial disorders, respectively.

  5. Dosimetry on ocular brachytherapy with I-125 ophthalmologic ROPES and COMS plaques

    Energy Technology Data Exchange (ETDEWEB)

    Mourao, Arnaldo P. [Centro Federal de Educacao Tecnoloica de Minas Gerais (CEFET-MG), Belo Horizonte, MG (Brazil). Nucleo de Engenharia Hospitalar], e-mail: aprata@des.cefetmg.br; Campos, Tarcisio P.R. [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Programa de Pos-graduacao em Ciencias e Tecnicas Nucleares], e-mail: campos@nuclear.ufmg.br

    2009-07-01

    Radiotherapy is an alternative to ocular enucleation. However, the irradiation of ocular region can bring deleterious effects due to the high doses, mainly in the lens, retina and in the bone structures in growth phase. Brachytherapy instead of teletherapy looks for departuring absorbed doses in tumor minimizing doses in the lens and the adjacent tissues of the eyeball (orbital region), avoiding deleterious effects. Thus, a three-dimensional computational voxel model and an analytical model were coupled, including the heterogeneous properties of the globe and the adjacent tissues. The analytical model was applied to define the thin structures of the ocular globe. This computational model is used to simulate orbital irradiation with ROPES and COMS ophthalmologic plaques placed on the sclera surface filled to ten and eight iodine-125 seeds, respectively. Simulations are performed on the MCNP5 code. The computational simulation allows evaluating how the dose rates are spatially distributed in the orbital volume. The results are normalized to 100% at the maximum dose on the tumor base, and by the applied source activity. The external globe structures receive 0.5% of the maximum internal dose. The crystalline lens dosimetry depends on the position and thickness of the tumor and the plaque diameters. On the present case, 12.75% of maximum dose is found on the lens. The maximum dose is found onto the eyeball, in the vitreous. The present model represents an advance in simulating and predicting absorbed dose on ocular brachytherapy, incorporating anthropomorphic and anthropometric features of the real eyeball. (author)

  6. Effectiveness of skeleton handouts during ophthalmology theory lectures for undergraduate medical students

    Science.gov (United States)

    Prabhu, Venkatesan; Sahoo, Soumendra; Soe, Htoo Htoo Kyaw

    2015-01-01

    Background: Although lecture handouts are commonly given to students during theory lectures, students’ perception, as well as their performance, can vary depending on the type of handouts they receive for information processing. Methodology: This is a quasi-experimental study involving 6th semester medical students. The study was conducted during theory lectures on ophthalmology. The two types of notes given to the students were comprehensive handout and a skeleton handout, which included some lecture notes but required substantial annotation by the students. Pre-test and post-test in the form of multiple choice questions were conducted before and after the lecture session, respectively. Results: There was a significant difference of mean score of pre- and post-test between skeletal handout (pre = 1.85 ± 1.275, post = 4.85 ± 0.363) and full handout (pre = 1.92 ± 1.09 post = 2.61 ± 0.771) with P < 0.001. However, the students’ responses to questionnaires indicated a strong preference for much detailed handouts as essential to preparation for examinations. Conclusion: The student can improve their performance during examination while working on skeletal handouts during theory lectures in spite of showing a preference for complete handouts. PMID:26380205

  7. [Curse and blessing of combat ophthalmology in the 20th and 21st centuries].

    Science.gov (United States)

    Gümbel, H

    2009-08-01

    Combat injuries in the literature are dominated by reports on the rescue of life and body trauma treatment of casualties. In the 20th and 21st centuries, preservation of the eyes would be more and more an extremely important goal. In World War I and II and along with the trends in current warfare, automatic weapons and conventional munitions like shrapnel will continue to cause a significant percentage of all ocular trauma in combat. There are also laser weapons which have the potential to cause blinding eye injuries. In spite of the curse of war there are also blessings of combat ophthalmology like the invention of the intraocular lens after the Second World War, when the plexiglas of a broken cockpit canopy was found to be inert in penetrating eye injuries. A significant ly better eye protection was developed following terror attacks, such as terrorist blasts in the 21st century. Finally, every new generation of military ophthalmologists has had to learn on its own from earlier armed conflicts and some of this knowledge could be helpful for our patients in more peaceful times. Georg Thieme Verlag KG Stuttgart.New York.

  8. I-Maculaweb: A Tool to Support Data Reuse in Ophthalmology.

    Science.gov (United States)

    Bonetto, Monica; Nicolò, Massimo; Gazzarata, Roberta; Fraccaro, Paolo; Rosa, Raffaella; Musetti, Donatella; Musolino, Maria; Traverso, Carlo E; Giacomini, Mauro

    2016-01-01

    This paper intends to present a Web-based application to collect and manage clinical data and clinical trials together in a unique tool. I-maculaweb is a user-friendly Web-application designed to manage, share, and analyze clinical data from patients affected by degenerative and vascular diseases of the macula. The unique and innovative scientific and technological elements of this project are the integration with individual and population data, relevant for degenerative and vascular diseases of the macula. Clinical records can also be extracted for statistical purposes and used for clinical decision support systems. I-maculaweb is based on an existing multilevel and multiscale data management model, which includes general principles that are suitable for several different clinical domains. The database structure has been specifically built to respect laterality, a key aspect in ophthalmology. Users can add and manage patient records, follow-up visits, treatment, diagnoses, and clinical history. There are two different modalities to extract records: one for the patient's own center, in which personal details are shown and the other for statistical purposes, where all center's anonymized data are visible. The Web-platform allows effective management, sharing, and reuse of information within primary care and clinical research. Clear and precise clinical data will improve understanding of real-life management of degenerative and vascular diseases of the macula as well as increasing precise epidemiologic and statistical data. Furthermore, this Web-based application can be easily employed as an electronic clinical research file in clinical studies.

  9. Neuro-Behçet’s disease in childhood: A focus on the neuro-ophthalmological features

    Directory of Open Access Journals (Sweden)

    Mora Paolo

    2013-01-01

    Full Text Available Abstract Neuro-Behçet’s disease (NBD involves the central nervous system; peripheral nervous system involvement is not often reported. NBD is quite common in adult patients and occurs rarely during childhood and adolescence. Young patients may share symptoms and signs of NBD with other neuro-ophthalmological disorders (e.g. idiopathic intracranial hypertension; thus, making the differential diagnosis difficult. Neuroimaging is mandatory and necessary for a correct NBD diagnosis but in children radiological examinations are often difficult to perform without sedation. From 1971 to 2011, 130 patients aged ≤16 years have been reported with NBD, according to retrospective surveys, case series, and case reports. The origin of the reported cases met the well-known geographical distribution of Behçet’s disease (BD; the mean age at presentation of neurological findings was 11.8 years, with male gender prevalence (ratio, 2.9:1. We considered in detail the neuro-ophthalmological features of the 53 cases whose neuroimaging alterations were described with an assigned radiological pattern of the disease (parenchymal: 14 cases, non-parechymal: 35 cases, and mixed: 4 cases. In 19/53 patients (36%, neuro-ophthalmological symptoms anticipated any pathognomonic sign for a BD diagnosis, or only occasional aphtae were recalled by the patients. Family history was positive in 17% of subjects. Headache was reported in 75% of the patients; in those presenting with cerebral vascular involvement, headache was combined to other symptoms of intracranial hypertension. Papilledema was the most frequently reported ophthalmological finding, followed by posterior uveitis. Treatment consisted of systemic steroids in 93% of patients, often combined with other immunosuppressive drugs (especially colchicine and azathioprine. Clinical recovery or improvement was documented in the large majority of patients. Nine subjects had definitive alterations, and one died. Based on our

  10. eOftalmología: estado actual y tendencias futuras eOphthalmology: current state and future tendencies

    Directory of Open Access Journals (Sweden)

    J. Andonegui

    2010-04-01

    Full Text Available La eSalud se puede definir como el uso de las tecnologías de la información y las comunicaciones para proporcionar o apoyar un diverso grupo de actividades relacionadas con la atención en salud. Si este concepto se traslada a la atención oftalmológica sería lo que denominamos como eOftalmología. En este artículo se describe el estado actual de los modelos de eOftalmología en el cribado de la retinopatía diabética y el diagnóstico y el seguimiento del glaucoma crónico y la degeneración macular asociada a la edad. También se definen los requerimientos tecnológicos necesarios para implantar este tipo de modelos de asistencia, se discuten las ventajas derivadas de los mismos y se hace una previsión del impacto que la eOftalmología puede tener en el futuro de la asistencia sanitaria.eOphthalmology can be defined as the use of information and telecommunications technologies to provide or support a group of activities related to ophthalmic care. The same concept applied to ophthalmic care would be eOphthalmology. This paper describes the current state of eOphthalmology-based models in diabetic retinopathy screening and in the diagnosis and follow-up of chronic glaucoma and age-related macular degeneration. Furthermore, the main advantages of these models and the technological requirements needed for their implementation are described. Finally, a prediction of the impact of eOphthalmology on the future of health care is offered.

  11. 关于眼科学教学团队建设的思考%Thinking about ophthalmology teaching team building

    Institute of Scientific and Technical Information of China (English)

    钟一声; 沈玺

    2013-01-01

    Building high performance teaching team of ophthalmology has a very important role for teachers' professional development and the improvement of the quality of ophthalmology personnel training. In this paper, the situation and existing problems of ophthalmology teaching team, the meaning of building ophthalmology teaching team, and the strategies for building team were considered.%建设高绩效的眼科教学团队,对于眼科教师的专业发展和人才培养质量的提高具有十分重要的作用.文章就眼科教学团队建设现状及存在的问题,眼科教学团队建设的意义及建设策略进行了思考.

  12. Stem Cell Ophthalmology Treatment Study (SCOTS): bone marrow-derived stem cells in the treatment of Leber's hereditary optic neuropathy

    Science.gov (United States)

    Weiss, Jeffrey N.; Levy, Steven; Benes, Susan C.

    2016-01-01

    The Stem Cell Ophthalmology Treatment Study (SCOTS) is currently the largest-scale stem cell ophthalmology trial registered at ClinicalTrials.gov (identifier: NCT01920867). SCOTS utilizes autologous bone marrow-derived stem cells (BMSCs) to treat optic nerve and retinal diseases. Treatment approaches include a combination of retrobulbar, subtenon, intravitreal, intra-optic nerve, subretinal, and intravenous injection of autologous BMSCs according to the nature of the disease, the degree of visual loss, and any risk factors related to the treatments. Patients with Leber's hereditary optic neuropathy had visual acuity gains on the Early Treatment Diabetic Retinopathy Study (ETDRS) of up to 35 letters and Snellen acuity improvements from hand motion to 20/200 and from counting fingers to 20/100. Visual field improvements were noted. Macular and optic nerve head nerve fiber layer typically thickened. No serious complications were seen. The increases in visual acuity obtained in our study were encouraging and suggest that the use of autologous BMSCs as provided in SCOTS for ophthalmologic mitochondrial diseases including Leber's hereditary optic neuropathy may be a viable treatment option. PMID:27904503

  13. Trends in ophthalmology journals: a five-year bibliometric analysis (2009-2013

    Directory of Open Access Journals (Sweden)

    Christopher B. Schulz

    2016-12-01

    Full Text Available AIM: To explore the trends in the ophthalmic literature over a 5-year period in relation to country, research expenditure and demographics. METHODS: Articles published between 2009 and 2013 by the 20highest-contributing countries in the 20 top-ranked ophthalmology journals were identified by their country of affiliation. The number of articles published and mean impact factor were measured per country for each year and trends explored using regression analysis with 5-year and 10-year forecasts calculated. Data on research expenditure was collected and tested for correlation with the number of articles and mean impact factor. RESULTS: The analysis included 19 338 articles. The USA, UK and Europe accounted for 60.2% of articles published, with the USA contributing 7388 articles (34.0%. The USA also demonstrated the highest mean impact factor (3.5. Research expenditure was significantly correlated with both research output (r=0.86, P<0.001 and scholarly impact (r=0.42, P<0.001. China (P<0.01, Korea (P<0.01 and India (P<0.02 demonstrated a significant growth in research output over the study period. The research contribution of these three countries combined is forecasted to overtake that of Europe within ten years, with China expected to be the second-largest contributor within five years. These countries were also among those demonstrating the greatest growth in research expenditure. CONCLUSION: While the USA and European countries are major contributors of ophthalmic research, the productivity of some Asian countries is growing impressively. The contribution of China, Korea and India is forecasted to outweigh that of Europe by 2023. Research expenditure is highly correlated with research productivity and these trends reflect the differing economic priorities across the world.

  14. Effect of co-management with Internal Medicine on hospital stay in Ophthalmology.

    Science.gov (United States)

    Montero Ruiz, E; Rebollar Merino, A; Castejón Cervero, M A; Barbero Allende, J M; Culebras López, A; García Sánchez, M

    2015-06-01

    Patients admitted to the Department of Ophthalmology (OPH) are of increasing age, comorbidity and complexity, leading to increased consultations/referrals to Internal Medicine (IM). An alternative to consultations/referrals is co-management. The effect of co-management on length of hospital stay was studied in patients admitted to OPH. Retrospective observational study was performed that included patients ≥14 years old discharged from OPH between 1 January 2009 and 30 June 2013, who were co-managed from May 2011. An analysis was made including age, sex, type of admission, whether it was operated on, administrative weight associated with GRD, total number of discharge diagnoses, Charlson comorbidity index (CCI), mortality, readmissions, and LoS. There were statistically significant differences between the groups in operated patients (odds ratio [OR] 2.3, 95% confidence interval [95% CI] 1.5 to 3.6), administrative weight (0.1160; 95% CI 0.0738 to 0.1583), and number of diagnoses (0.9, 95% CI 0.5 to 1.3). On adjustment, co-management reduced LoS in OPH by 27.8%, 0.5 days (95% CI 0.1 to 1). Patients admitted to OPH have increasing comorbidity and complexity. Co-management is associated with a reduced LoS and costs in OPH, similar to that observed in other surgical services. Copyright © 2014 Sociedad Española de Oftalmología. Published by Elsevier España, S.L.U. All rights reserved.

  15. Small-gauge pars plana vitrectomy: a report by the American Academy of Ophthalmology.

    Science.gov (United States)

    Recchia, Franco M; Scott, Ingrid U; Brown, Gary C; Brown, Melissa M; Ho, Allen C; Ip, Michael S

    2010-09-01

    To review available peer-reviewed publications to evaluate the safety profile and visual outcomes associated with small-gauge pars plana vitrectomy. Literature searches of the PubMed and the Cochrane Library databases were last conducted on August 5, 2009, with no date restrictions. The searches were limited to articles published in English. These searches retrieved 328 articles, of which 76 were deemed topically relevant and rated according to strength of evidence. On the basis of level II and level III evidence, the overall safety profile of small-gauge pars plana vitrectomy is similar to that established for conventional 20-gauge pars plana vitrectomy and provides comparable visual acuity results. An increased incidence of infectious endophthalmitis after 25-gauge vitrectomy was reported in 2 comparative studies, but this was not found in multiple, larger, more recent studies, perhaps due to modifications in case selection and surgical technique over time. Compared with 20-gauge vitrectomy, small-gauge vitrectomy is associated with significantly lower levels of patient discomfort and ocular inflammation, and the time required for improvement in visual acuity is shorter. The technological advances of small-gauge vitrectomy seem to afford visual benefit comparable with that seen with traditional 20-gauge surgery, with more rapid healing, less discomfort, and an acceptably low incidence of adverse events comparable with those observed with conventional 20-gauge vitrectomy. As surgical techniques evolve and clinical experience grows, continued close surveillance is necessary for an accurate assessment of complications. Copyright © 2010 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  16. Hydrogen research in ophthalmology%氢气眼科医学研究进展

    Institute of Scientific and Technical Information of China (English)

    齐林嵩

    2014-01-01

    Oxidative stress is thought to be associated with many common ophthalmic diseases.Recently studies showed that hydrogen is an antioxidant,and it can selectively reduce the hydroxyl radicals and therefore is used to the prevention and treatment of many diseases,such as retinal neovascularization disease,diabetic retinopathy,retinal ischemia-reperfusion injury,retinal light-injury,etc.Also,hydrogen has a small molecular weight and good water-and lipid-solubility,so it can diffuse freely through the cell membrane toward organelles like mitochondria to exert its treating effect.The research progresses in the application of hydrogen in ophthalmology were summarized.%氧化应激与眼科多种疾病的发生、发展密切相关.近来研究发现,氢气是一种选择性的抗氧化物质,在治疗和预防多种疾病,如视网膜新生血管病变、糖尿病视网膜病变、视网膜缺血-再灌注损伤、化学烧伤及光损伤等方面都有所应用.氢气还具有相对分子质量小、水溶性和脂溶性良好、可通过自由扩散穿透细胞膜到达线粒体等靶向细胞器的优势.就氢气在眼科医学领域的研究进展及氢气的给药方式等进行综述.

  17. Utilization of Portable Radios to Improve Ophthalmology Clinic Efficiency in an Academic Setting.

    Science.gov (United States)

    Davis, Alexander S; Elkeeb, Ahmed M; Vizzeri, Gianmarco; Godley, Bernard F

    2016-03-01

    Improvement in clinic efficiency in the ambulatory setting is often looked at as an area for development of lean management strategies to deliver a higher quality of healthcare while reducing errors, costs, and delays. To examine the benefits of improving team communication and its impact on clinic flow and efficiency, we describe a time-motion study performed in an academic outpatient Ophthalmology clinic and its objective and subjective results. Compared to clinic encounters without the use of the portable radios, objective data demonstrated an overall significant decreases in mean workup time (15.18 vs. 13.10), room wait (13.10 vs. 10.47), and decreased the total time needed with an MD per encounter (9.45 vs. 6.63). Subjectively, significant improvements were seen in careprovider scores for patient flow (60.78 vs. 84.29), getting assistance (61.89 vs. 88.57), moving patient charts (54.44 vs. 85.71), teamwork (69.56 vs. 91.0), communications (62.33 vs. 90.43), providing quality patient care (76.22 vs. 89.57), and receiving input on the ability to see walk-in patients (80.11 vs. 90.43). For academic purposes, an improvement in engagement in patient care and learning opportunities was noted by the clinic resident-in-training during the pilot study. Portable radios in our pilot study were preferred over the previous method of communication and demonstrates significant improvements in certain areas of clinical efficiency, subjective perception of teamwork and communications, and academic learning.

  18. Neuro-ophthalmology of invasive fungal sinusitis: 14 consecutive patients and a review of the literature.

    Science.gov (United States)

    Thurtell, Matthew J; Chiu, Alison L S; Goold, Lucy A; Akdal, Gulden; Crompton, John L; Ahmed, Rebekah; Madge, Simon N; Selva, Dinesh; Francis, Ian; Ghabrial, Raf; Ananda, Arj; Gibson, John; Chan, Raymond; Thompson, Elizabeth O; Rodriguez, Michael; McCluskey, Peter J; Halmagyi, G Michael

    2013-08-01

    Invasive fungal sinusitis is a rare condition that usually occurs in immunocompromised patients and often presents as an orbital apex syndrome. It is frequently misdiagnosed on presentation and is almost always lethal without early treatment. Retrospective case series of 14 consecutive patients with biopsy-proven invasive fungal sinusitis from four tertiary hospitals. Fourteen patients (10 men and 4 women; age range 46-82 years). Retrospective chart review of all patients presenting with invasive fungal sinusitis between 1994 and 2010 at each hospital, with a close analysis of the tempo of the disease to identify any potential window of opportunity for treatment. Demographic data, background medical history (including predisposing factors), symptoms, signs, radiological findings, histopathological findings, treatment approach and subsequent clinical course were recorded and analysed. Only one patient was correctly diagnosed at presentation. Only two patients were not diabetic or immunocompromised. The tempo was acute in two patients, subacute in nine patients and chronic in three patients. In the subacute and chronic cases, there was about 1 week of opportunity for treatment, from the time there was a complete orbital apex syndrome, and still a chance for saving the patient, to the time there was central nervous system invasion, which was invariably fatal. Only two patients survived - both had orbital exenteration, as well as antifungal drug treatment. Invasive fungal sinusitis can, rarely, occur in healthy individuals and should be suspected as a possible cause of a progressive orbital apex syndrome. © 2012 The Authors. Clinical and Experimental Ophthalmology © 2012 Royal Australian and New Zealand College of Ophthalmologists.

  19. Neuro-Ophthalmological Findings in Children and Adolescents with Chronic Ataxia

    Science.gov (United States)

    Salman, Michael S.; Chodirker, Bernard N.

    2015-01-01

    Abstract Chronic ataxia is a challenging problem in paediatric neurology. It is caused by a multitude of disorders that at least initially have similar or non-specific phenotype. Some of these disorders have associated neuro-ophthalmological signs (N-OS). The aims of this study are to describe the N-OS and their frequencies in general and by disease aetiology in paediatric patients with chronic ataxia. The authors identified 184 patients under age 17 years with chronic ataxia (>2 months duration or recurrent) during 1991–2008 from multiple sources. Diagnoses and N-OS were ascertained following charts review. Mean age (SD) was 15 (7.7) years. Median duration of follow-up was 6.4 years. There were 214 N-OS in 115 patients (median = 2, range = 1–5 N-OS/patient). Strabismus was present in 29.3% of patients, nystagmus 27.7%, impaired smooth pursuit 23.4%, hypometric saccades 10.3%, decreased visual acuity 9.2%, abnormal optic discs 8.7%, abnormal pupillary examination 2.7%, hypermetric saccades 2.2%, impaired ductions 1.6%, and abnormal visual fields in 1.1% of patients. N-OS were reported most commonly among patients with the following disorders (commonest N-OS): hypoxic-ischaemic encephalopathy following birth (strabismus), episodic ataxia (nystagmus), neuronal ceroid lipofuscinosis (abnormal optic discs), neuronal migration disorder (strabismus), ischaemic stroke (nystagmus), Joubert syndrome–related disorders (strabismus), leukodystrophy (nystagmus), Friedreich ataxia (hypometric saccades, impaired smooth pursuit, nystagmus), mitochondrial disease (strabismus, nystagmus), ataxia telangiectasia (impaired smooth pursuit), and Angelman syndrome (strabismus). N-OS occur commonly in children with chronic ataxia. Although non-specific, they vary with disease aetiology, potentially aiding in the assessment of these patients. PMID:27928345

  20. Frequency and risk factors associated with dry eye in patients attending a tertiary care ophthalmology center in Mexico City

    Science.gov (United States)

    Martinez, Jaime D; Galor, Anat; Ramos-Betancourt, Nallely; Lisker-Cervantes, Andrés; Beltrán, Francisco; Ozorno-Zárate, Jorge; Sánchez-Huerta, Valeria; Torres-Vera, Marco-Antonio; Hernández-Quintela, Everardo

    2016-01-01

    Purpose The purpose of this study was to ascertain the frequency and risk factors of dry eye (DE) among patients attending a tertiary care ophthalmology center in Mexico. Methods Approximately 338 consecutive new patients attending a tertiary care ophthalmology center in Mexico City underwent an ocular surface examination, which included tear film break-up time, fluorescein corneal staining, Schirmer’s test, and evaluation of meibum quality. Symptoms of DE were evaluated by the Ocular Surface Disease Index and Dry Eye Questionnaire-5. Information on demographics, exposures, past medical and ocular history, and medications was also collected. Results The frequency of severe DE symptoms was found to be 43% based on the Ocular Surface Disease Index and 30% based on Dry Eye Questionnaire-5. Risk factors significantly associated with increased DE symptoms included dry mouth and gastrointestinal ulcer medications. With regard to signs, aqueous tear deficiency was a less-frequent finding (22%) in our population than evaporative deficiency (94%). Risk factors associated with aqueous tear deficiency were dry mouth and diuretic use. No risk factors were associated with evaporative deficiency. Risk factors associated with meibomian gland dysfunction included old age, male sex, arthritis, and use of an antihypertensive. The only risk factor associated with corneal staining was dry mouth. Conclusion This is the first study to demonstrate the frequency of symptomatic and clinical DE in a tertiary care ophthalmology center in Mexico. The frequency of DE ranged from 30% using a symptomatic definition to 94% using objective measures. Different risk factors were found for different aspects of DE, suggesting differing underlying pathophysiologies behind different DE subtypes. PMID:27499613

  1. An analysis of ophthalmology services in Finland - has the time come for a Public-Private Partnership?

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    Lehto Juhani

    2009-11-01

    Full Text Available Abstract Background We studied the prerequisites for Public-Private Partnership (PPP in the context of the Finnish health care system and more specifically in the field of ophthalmology. PPP can be defined as a more or less permanent cooperation between public and private actors, through which the joint products or services are developed and in which the risks, costs and profits are shared. The Finnish eye care services system is heterogeneous with several different providers and can be regarded as sub-optimal in terms of overall resource use. What is more, the public sector is suffering from a shortage of ophthalmologists, which further decreases its possibilities to meet the present needs. As ophthalmology has traditionally been a medical specialty with a substantial private sector involvement in service provision, PPP could be a feasible policy to be used in the field. We thus ask the following research question: Is there, and to what extent, an open window of opportunity for PPP? Methods In addition to the previously published literature, the research data consisted of 17 thematic interviews with public and private experts in the field of ophthalmology. The analysis was conducted in two stages. First, a literature-based content analysis was used to explore the prerequisites for PPP. Second, Kingdon's (1995 multiple streams theory was used to study the opening of the window of opportunity for PPP. Results Public and private parties reported similar problems in the current situation but defined them differently. Also, there is no consensus on policy alternatives. Public opinion seems to be somewhat uncertain as to the attitudes towards private service providers. The analysis thus showed that although there are prerequisites for PPP, the time has not yet come for a Public-Private Partnership. Conclusion Should the window open fully, the emergence of policy entrepreneurs and an opportunity for a win-win situation between public and private

  2. The importance of timely ophthalmologic examination in preterm infants at risk of retinopathy occurrence

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    Knežević Sanja

    2012-01-01

    Full Text Available Background/Aim. Retinopathy of prematurity (ROP is a multifactorial disease in premature infants. The aim of this study was to determine the incidence of ROP in children treated at the Center of Neonatology, Pediatric Clinic, Clinical Center in Kragujevac, Serbia. Methods. The study covered all children with birth weight below 2,000 g and/or gestational age below the 37th week, who from June 2006 to December 2009 underwent ophthalmological examination for ROP. The results of fundoscopy were classified in accordance with the International Classification of ROP. The treatment of infants and those with ROP was conducted in accordance with the early treatment of ROP study recommendations. We analyzed gestational age, birth weight and postconceptional age in two groups: healthy infants and those with severe form of ROP. Statistical analysis was performed using the SPSS 16. Results. A total of 478 children met the criteria of screening for ROP. Severe stage of ROP, which required laser treatment, had 102 (21.3% children. Out of the infants with severe ROP 14 (13.7% of the infants with APD had aggressive posterior disease, while two (0.4% remained blind. The differences in the mean values of gestational age between the healthy and the children with severe form of the disease were statistically significant (p < 0.0005. The mean value of gestational age for the healthy children was 33.33 ± 2.28 weeks and for the seek infants 30.66 ± 2.79 weeks. The mean value of the weight in healthy children was 1.981 ± 407 g, and in sick children 1.535 ± 434 g which was statistically significant (p < 0.0005. Multivariate binary logistic regression showed that the occurrence of the disease depends on body weight and gestational age. Conclusion. The incidence of severe forms of ROP was 21.3%. Aggressive form of ROP was present in 13.7% of the children. The cut-off value for body weight was 1.740 g, and for gestational age 32.5 weeks.

  3. UR Well Eye Care: a model for medical student ophthalmology education and service in the community

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    MacLean K

    2014-11-01

    .Conclusion: Student-run eye clinics provide a longitudinal setting where students can receive one-on-one training with attending ophthalmologists, attain a broad clinical exposure, and provide a needed service in their communities. Keywords: medical student education, student-run clinic, student-run eye clinic, volunteer eye clinic, ophthalmology education

  4. Disinfection of Tonometers: A Report by the American Academy of Ophthalmology.

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    Junk, Anna K; Chen, Philip P; Lin, Shan C; Nouri-Mahdavi, Kouros; Radhakrishnan, Sunita; Singh, Kuldev; Chen, Teresa C

    2017-07-11

    (dilute bleach) offers effective disinfection against adenovirus and HSV, the viruses commonly associated with nosocomial outbreaks in eye care. Tonometer prisms should be examined regularly for signs of damage. Copyright © 2017 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  5. A comparison of undergraduate clinical ophthalmology learning methods: smart phone television display versus slit-lamp teaching telescope.

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    Wenting, Sandy Zhou; Samin, Margaret Million; Sanjay, Srinivasan; Neelam, Kumari; Shibli, Khalil; Chang, Su; Cheng, Jason

    2017-08-01

    To compare medical students' preference of smart phone television display (SPTD) to a slit-lamp teaching telescope (SLTT) in undergraduate clinical ophthalmology education. This is a randomized, crossover, comparative study. Pairs of medical students were randomly assigned to 2 teaching sessions using either SPTD first followed by SLTT or in reverse order. Students were asked to give feedback on the 2 teaching devices by answering 6 questions using a numeric rating score from 1 to 10. All participating students were sent the results of the study 1 month after the completion of the study and were asked to reflect upon the outcome. Thirty-eight students were recruited. The overall satisfaction scores were significantly higher for SPTD than SLTT (8.6 ± 1.4 vs 7.5 ± 1.0, p < 0.01). The students preferred SPTD compared with SLTT in terms of "visualization" (8.5 ± 1.4 vs 7.0 ± 1.3, p < 0.01), "ocular sign description" (8.4 ± 1.3 vs 7.2 ± 1.2, p < 0.01), "ocular anatomy understanding" (8.3 ± 1.2 vs 7.6 ± 1.2, p < 0.01), and "confidence in identifying clinical signs" (8.4 ± 1.2 vs 7.5 ± 1.2, p < 0.01). A larger proportion of the students gave higher scores to SPTD compared with SLTT in all questions. All students who responded to the follow-up questionnaire (n = 14) agreed with our interpretation of the data and would support the use of SPTD in undergraduate clinical ophthalmology teaching. Our study has demonstrated that the utility of SPTD as a teaching aid can significantly increase the satisfaction of undergraduate medical students during their ophthalmology attachment. It offers specific practical advantages in teaching medical students over the traditional SLTT. Copyright © 2017 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights reserved.

  6. Frequency and risk factors associated with dry eye in patients attending a tertiary care ophthalmology center in Mexico City

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    Martinez JD

    2016-07-01

    Full Text Available Jaime D Martinez,1 Anat Galor,2,3 Nallely Ramos-Betancourt,1 Andrés Lisker-Cervantes,1 Francisco Beltrán,1 Jorge Ozorno-Zárate,1 Valeria Sánchez-Huerta,1 Marco-Antonio Torres-Vera,1 Everardo Hernández-Quintela1 1Cornea and External Diseases Service, Asociación Para Evitar la Ceguera en Mexico (Association to prevent blindness in Mexico, Universidad Nacional Autónoma de México, Mexico City, Mexico; 2Department of Ophthalmology, Miami Veterans Affairs Medical Center, 3Cornea and External Diseases Division, Bascom Palmer Eye Institute, University of Miami, Miami, FL, USA Purpose: The purpose of this study was to ascertain the frequency and risk factors of dry eye (DE among patients attending a tertiary care ophthalmology center in Mexico.Methods: Approximately 338 consecutive new patients attending a tertiary care ophthalmology center in Mexico City underwent an ocular surface examination, which included tear film break-up time, fluorescein corneal staining, Schirmer’s test, and evaluation of meibum quality. Symptoms of DE were evaluated by the Ocular Surface Disease Index and Dry Eye Questionnaire-5. Information on demographics, exposures, past medical and ocular history, and medications was also collected.Results: The frequency of severe DE symptoms was found to be 43% based on the Ocular Surface Disease Index and 30% based on Dry Eye Questionnaire-5. Risk factors significantly associated with increased DE symptoms included dry mouth and gastrointestinal ulcer medications. With regard to signs, aqueous tear deficiency was a less-frequent finding (22% in our population than evaporative deficiency (94%. Risk factors associated with aqueous tear deficiency were dry mouth and diuretic use. No risk factors were associated with evaporative deficiency. Risk factors associated with meibomian gland dysfunction included old age, male sex, arthritis, and use of an antihypertensive. The only risk factor associated with corneal staining was dry

  7. The History, Role, and Value of Public Directors on Certifying Boards: The American Board of Ophthalmology Experience.

    Science.gov (United States)

    Anderson, Suzanne T; Nora, Lois M; McEntee, Christine W; Fitzgerald, Matthew E; Nugent, Samantha Guastella

    2016-09-01

    The mission of the American Board of Ophthalmology (ABO) is to serve the public by improving the quality of ophthalmic practice through a continuing certification process that fosters excellence and encourages continual learning. Since 2001, achieving this mission has been enhanced by including public directors in the ABO governance. We review the evolution of including nonprofessional members on the governing boards of professional regulatory and self-regulatory organizations generally, provide history about the incorporation of non-professional public directors into the governance structure of the American Board of Medical Specialties and the ABO, and offer insights about the perceived impact of public directors on the ABO.

  8. Adoption of electronic health records and preparations for demonstrating meaningful use: an American Academy of Ophthalmology survey.

    Science.gov (United States)

    Boland, Michael V; Chiang, Michael F; Lim, Michele C; Wedemeyer, Linda; Epley, K David; McCannel, Colin A; Silverstone, David E; Lum, Flora

    2013-08-01

    To assess the current state of electronic health record (EHR) use by ophthalmologists, including adoption rate, user satisfaction, functionality, benefits, barriers, and knowledge of meaningful use criteria. Population-based, cross-sectional study. A total of 492 members of the American Academy of Ophthalmology (AAO). A random sample of 1500 AAO members were selected on the basis of their practice location and solicited to participate in a study of EHR use, practice management, and image management system use. Participants completed the survey via the Internet, phone, or fax. The survey included questions about the adoption of EHRs, available functionality, benefits, barriers, satisfaction, and understanding of meaningful use criteria and health information technology concepts. Current adoption rate of EHRs, user satisfaction, benefits and barriers, and availability of EHR functionality. Overall, 32% of the practices surveyed had already implemented an EHR, 15% had implemented an EHR for some of their physicians or were in the process of implementation, and another 31% had plans to do so within 2 years. Among those with an EHR in their practice, 49% were satisfied or extremely satisfied with their system, 42% reported increased or stable overall productivity, 19% reported decreased or stable overall costs, and 55% would recommend an EHR to a fellow ophthalmologist. For those with an electronic image management system, only 15% had all devices integrated, 33% had images directly uploaded into their system, and 12% had electronic association of patient demographics with the image. The adoption of EHRs by ophthalmology practices more than doubled from 2007 to 2011. The satisfaction of ophthalmologists with their EHR and their perception of beneficial effects on productivity and costs were all lower in 2011 than in 2007. Knowledge about meaningful use is high, but the percentage of physicians actually receiving incentive payments is relatively low. Given the importance

  9. The Global Education Network for Retinopathy of Prematurity (Gen-Rop): Development, Implementation, and Evaluation of A Novel Tele-Education System (An American Ophthalmological Society Thesis).

    Science.gov (United States)

    Chan, R V Paul; Patel, Samir N; Ryan, Michael C; Jonas, Karyn E; Ostmo, Susan; Port, Alexander D; Sun, Grace I; Lauer, Andreas K; Chiang, Michael F

    2015-01-01

    To describe the design, implementation, and evaluation of a tele-education system developed to improve diagnostic competency in retinopathy of prematurity (ROP) by ophthalmology residents. A secure Web-based tele-education system was developed utilizing a repository of over 2,500 unique image sets of ROP. For each image set used in the system, a reference standard ROP diagnosis was established. Performance by ophthalmology residents (postgraduate years 2 to 4) from the United States and Canada in taking the ROP tele-education program was prospectively evaluated. Residents were presented with image-based clinical cases of ROP during a pretest, posttest, and training chapters. Accuracy and reliability of ROP diagnosis (eg, plus disease, zone, stage, category) were determined using sensitivity, specificity, and the kappa statistic calculations of the results from the pretest and posttest. Fifty-five ophthalmology residents were provided access to the ROP tele-education program. Thirty-one ophthalmology residents completed the program. When all training levels were analyzed together, a statistically significant increase was observed in sensitivity for the diagnosis of plus disease, zone, stage, category, and aggressive posterior ROP (Peducation system for ROP education is effective in improving diagnostic accuracy of ROP by ophthalmology residents. This system may have utility in the setting of both healthcare and medical education reform by creating a validated method to certify telemedicine providers and educate the next generation of ophthalmologists.

  10. Repercusión oftalmológica de los traumatismos maxilofaciales Ophthalmological repercussion of maxillofacial traumatisms

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    José Manuel Díaz Fernández

    2004-12-01

    Full Text Available Se presenta un estudio prospectivo de 40 pacientes afectados por traumatismos maxilofaciales con lesiones oftalmológicas asociadas, asistidos en el Hospital Clinico quirúrgico Docente "Saturnino Lora" de Santiago de Cuba, durante el año 1995. La lesión oftalmológica más frecuente fue el hematoma palpebral, asociado con un porcentaje significativo de lesiones graves, las cuales estaban en relación con el área afectada durante el traumatismo. Se comportó con incidencia elevada la agudeza visual dentro de los límites normales. La secuela que más se presentó fue la cicatriz deformante de anejos. Se reportan casos de secuelas graves como la pérdida del globo ocular. Los estudios electrofisiológicos demostraron su importancia para la evaluación funcional de las lesiones oftalmológicas.prospective study of 40 patients suffering from maxillofacial traumatisms with associated ophthalmological injuries that recieved attention at "Saturnino Lora" Clinical and Surgical Teaching Hospital, in Santiago de Cuba, in 1995, was presented. The most frequent ophthalmological injury was the palpebral hematoma associated with a significant percentage of severe injuries, which were related to the area affected during traumatism. Visual acuity had an elevated incidence within the normal limits. The adnexa deforming scar was the most common sequela. Cases of severe sequelae, such as the loss of the eyeball, were reported.

  11. Control of psycho-physiological functions of students with ophthalmologic diseases in the process of physical education

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    V.M. Koryahin

    2017-01-01

    Full Text Available Purpose: to analyze dynamic of special health group students’ (having ophthalmologic diseases psychological functions parameters in physical education process. Material: in experiment 40 special health groups’ students with ophthalmologic diseases participated. Psycho-physiological tests and tool methodic were used. Results: numerical values of atenciony abilities at the beginning of the research witnessed about disharmony of information’s processing, transformation and storing by students. We observed general tendency to increase of test results, which in most of experimental group students (63.4% reached average level. Improvement of motor apparatus lability witnesses about adjustment of trophic and energetic processes as well as their vegetative regulation. Integrative indicator of attention stability was at average level (5 points at the beginning of the research. During experiment this indicator increased 2.7 times (10-11 points. We determined the presence of correlation between quickness of task’s fulfillment and efficiency coefficient (r=0.655. Conclusions: the received information is a foundation for effective interaction of physical education subjects in the form of personality-oriented technology.

  12. System of the ophthalmologic help premature children with retinopathy of prematurity in the Central region of Russia

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    A. V. Tereshchenko

    2012-01-01

    Full Text Available Purpose: Functional results analysis of ophthalmologic help system for premature infants, which includes the full cycle of early revelation, treatment and regular medical check-up activities for patients with ROP in Central region of Russia.Methods: Fields for ROP screening were performed in premature infants medical care units by clinic specialists. Infants with re- vealed ROP were directed to Kaluga Branch of IRtC «Eye Microsurgery» for detailed diagnostic examination and subsequent treatment and monitoring.Results: In 2003-2011 454 fields in Kaluga, tula, Bryansk, and Orel regions were made. 8861 infants were examined. ROP was found in 1834 infants (20.7%. 823 different interventions for infants with active ROP were performed: 737 retinal lasercoagulations, 3-ports vitrectomy — 72, lensvitrectomy — 14. the total efficacy of the treatment was 92.9%.Conclusion: the ophthalmologic help system for premature infants in Central region of Russia combines all directions from de-tailed diagnostic to hich-technology treatment. It allows to reproduce one all over the Russian Federation territory.

  13. System of the ophthalmologic help premature children with retinopathy of prematurity in the Central region of Russia

    Directory of Open Access Journals (Sweden)

    A. V. Tereshchenko

    2014-07-01

    Full Text Available Purpose: Functional results analysis of ophthalmologic help system for premature infants, which includes the full cycle of early revelation, treatment and regular medical check-up activities for patients with ROP in Central region of Russia.Methods: Fields for ROP screening were performed in premature infants medical care units by clinic specialists. Infants with re- vealed ROP were directed to Kaluga Branch of IRtC «Eye Microsurgery» for detailed diagnostic examination and subsequent treatment and monitoring.Results: In 2003-2011 454 fields in Kaluga, tula, Bryansk, and Orel regions were made. 8861 infants were examined. ROP was found in 1834 infants (20.7%. 823 different interventions for infants with active ROP were performed: 737 retinal lasercoagulations, 3-ports vitrectomy — 72, lensvitrectomy — 14. the total efficacy of the treatment was 92.9%.Conclusion: the ophthalmologic help system for premature infants in Central region of Russia combines all directions from de-tailed diagnostic to hich-technology treatment. It allows to reproduce one all over the Russian Federation territory.

  14. Stem Cell Ophthalmology Treatment Study (SCOTS):improvement in serpiginous choroidopathy following autologous bone marrow derived stem cell treatment

    Institute of Scientific and Technical Information of China (English)

    Jeffrey N Weiss; Susan C Benes; Steven Levy

    2016-01-01

    We report results in a 77-year-old male patient with visual loss from long-standing serpiginous choroidop-athy treated with bone marrow derived stem cells (BMSC) within the Stem Cell Ophthalmology Treatment Study (SCOTS). SCOTS is an Institutional Review Board approved clinical trial and the largest ophthal-mology stem cell study registered at the National Institutes of Health to date (ClinicalTrials.gov Identiifer:NCT01920867). Eight months after treatment by a combination of retrobulbar, subtenon, intravitreal and intravenous injection of BMSC, the patient’s best corrected Snellen acuity improved from 20/80– to 20/60+1 in the right eye and from 20/50– to 20/20–3 in the left eye. The Early Treatment of Diabetic Retinopathy Study (ETDRS) visual acuity continued to improve over the succeeding 8 months and the optical coherence tomography macular volume increased. The increases in visual acuity and macular volume are encouraging and suggest that the use of BMSC as provided in SCOTS may be a viable approach to treating serpiginous choroidopathy.

  15. Sida y oftalmología: una visión actual AIDS and ophthalmology: a contemporary view

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    E. Pérez-Blázquez

    2008-01-01

    Full Text Available La aparición del Síndrome de Inmunodeficiencia Adquirida (SIDA significó una revolución en medicina, de la que no es ajena la Oftalmología: la presencia rutinaria de patologías oftalmológicas hasta el momento excepcionales, como la retinitis por citomegalovirus (CMV, y la aparición de otras nuevas como la necrosis retiniana externa progresiva (NREP. La utilización generalizada de la terapia anterretroviral de gran actividad (TARGA, desde la segunda mitad de la década de los 90, produce un punto de inflexión a partir del cual la mejoría inmunológica de los pacientes con infección por el virus de la inmunodeficiencia humana (VIH provoca la disminución de casos con patología oftalmológica asociada a inmunodepresión (retinopatía VIH, retinitis por CMV, NREP…, y la mejoría espontánea de cuadros hasta entonces de evolución tórpida (sarcoma de Kaposi ocular, Molluscum palpebral…. Por contra, el continuo aumento de prevalencia de sífilis en estos pacientes se traduce en un aumento del número de casos de sífilis ocular, no asociados a inmunodepresión. También aparecen nuevas alteraciones oftalmológicas relacionadas con la TARGA: la uveítis por recuperación inmune en pacientes con retinitis CMV en remisión completa y el enoftalmos por atrofia de la grasa orbitaria en el contexto de la lipodistrofia, asociada a antirretrovirales. En la actualidad deben realizarse controles oftalmológicos preventivos en pacientes con inmunodepresión severa hasta confirmar un recuento de linfocitos CD4 por encima de 100 células/µl. Si además presentan retinopatía VIH, es aconsejable una revisión mensual hasta la recuperación inmune, dado el mayor riesgo de infección por CMV.The appearance of the Acquired Immune Deficiency Syndrome (AIDS meant a revolution in medicine, which has also affected Ophthalmology: the routine presence of ophthalmological pathologies which until then had been exceptional, such as retinitis due to

  16. Terapia celular nas doenças oftalmológicas Cell therapy in ophthalmology diseases

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    Rubens C. Siqueira

    2009-05-01

    Full Text Available Avanços no campo das células-tronco proporcionaram muita perspectiva para uso destas células na regeneração dos tecidos oculares danificados por doenças as quais não possuem tratamento disponível até o momento. Terapia baseada com células-tronco para regeneração e reparo ocular constitui uma esperança para a restauração da função visual em indivíduos com tecido oculares irreversivelmente danificados por doença ou trauma. Até o presente momento, somente as células LESC para o reparo da córnea apresentam aplicação clínica reconhecida no campo da oftalmologia. Experiências adquiridas com esta abordagem poderão potencialmente ajudar com o desenho de terapias baseadas em células-tronco para regenerar outros tecidos oculares particularmente a retina. Utilização de células-tronco adultas para tratamento de doenças degenerativas da retina tem sido testada e também sua viabilidade para utilização em humanos. Apesar de muitos problemas práticos, existe um otimismo geral entre a comunidade médica e científica que a terapia baseada nas células-tronco para restaurar a função visual pode tornar-se realidade em um futuro não muito distante. Neste manuscrito, foi realizada uma revisão do estado atual e limitações na aplicação de células-tronco para terapia ocular e consideramos as perspectivas futuras de seu uso na restauração da visão.Advances in the field of stem cell therapy have provided promising results in the regeneration of tissues damaged by eye diseases for which treatment is so far unavailable. Therapy based on stem cells to regenerate and repair is a hope for the restoration of visual function in individuals with ocular tissue irreversibly damaged by disease or trauma. Until now, only limbal epithelial stem cells have a recognized clinical application in ophthalmology for the repair of the cornea. Experience gained with this approach, may potentially help with the design of therapies based on stem

  17. Controversy in ophthalmology at the beginning of the 20th century: opinions voiced in the archives, especially on cataract and glaucoma.

    Science.gov (United States)

    Ravin, James G

    2011-01-01

    Volumes of the Archives of Ophthalmology from the early years of the 20th century include original articles as well as reports of proceedings of important ophthalmologic conferences held in the United States, Great Britain, and on the European continent. Original articles often provided new information, but speakers at conferences frequently offered lucid opinions on topics relevant to practitioners that were not found elsewhere in journals from that era, and these reports give us a sense of their thinking, particularly about therapeutic practices and knowledge of cataract and glaucoma.

  18. The Asia-Pacific Academy of Ophthalmology's Grand Rounds Around the World-An Online Educational Program Freely Accessible to All.

    Science.gov (United States)

    Lam, Dennis; Leung, Christopher; He, Mingguang; Tham, Clement; Liu, Yizhi; Pang, Calvin; Martin, Frank

    2012-01-01

    Grand rounds are excellent learning platforms for physicians and other health care professionals to keep up with important evolving areas in the management and treatment models of various diseases. However, there are hardly any freely accessible grand rounds in ophthalmology to meet the need for ophthalmic education in the Asia-Pacific region and beyond. The Asia-Pacific Academy of Ophthalmology would like to meet the need by sponsoring a new initiative "Grand Rounds Around the World" so that ophthalmologists and eye care professionals in the Asia-Pacific region and beyond can benefit from the program, leading to improved patient care and the elimination of learning barriers.

  19. Internal quality audit and quality standards as a method of quality improvement at the Department of Ophthalmology, University Hospital.

    Science.gov (United States)

    Nasić, Mirjana; Pokupec, Rajko; Katusić, Damir; Miklić, Pavle; Suić, Ivan; Galić, Slobodan

    2005-01-01

    Quality assessment of clinical health care with the programme of quality standard is a method of health management, through which better efficiency and safety of health outcomes can be achieved. In the period from 2002 to 2004, a pilot program of quality has been carried out on the Department of Ophthalmology, University Hospital Center in Zagreb. Seven internal audit teams of hospital commission and teams of hospital departments were evaluating introducing practice for quality standards every three months. In the period of two years improvement in all standards of quality has been noticed (expressed in percent of progress towards the ideal result of 100%): personnel 20%, patient rights 15%, medical equipment 40%, quality of emergency service 60%, implementation of clinical guidelines and criteria for elective admission 55%, quality of risk prevention 70%, quality of medical records 60%. The two-years-improvement dynamics of about 46%, first year 24%.

  20. An Overview of Ophthalmologic Survey Methodology in the 2008-2015 Korean National Health and Nutrition Examination Surveys.

    Science.gov (United States)

    Yoon, Kyung Chul; Choi, Won; Lee, Hyo Seok; Kim, Sang-Duck; Kim, Seung-Hyun; Kim, Chan Yun; Park, Ki Ho; Park, Young Jeung; Baek, Seung-Hee; Song, Su Jeong; Shin, Jae Pil; Yang, Suk-Woo; Yu, Seung-Young; Lee, Jong Soo; Lim, Key Hwan; Oh, Kyung Won; Kang, Se Woong

    2015-12-01

    The Korea National Health and Nutrition Examination Survey (KNHANES) is a national program designed to assess the health and nutritional status of the noninstitutionalized population of South Korea. The KNHANES was initiated in 1998 and has been conducted annually since 2007. Starting in the latter half of 2008, ophthalmologic examinations were included in the survey in order to investigate the prevalence and risk factors of common eye diseases such as visual impairment, refractive errors, strabismus, blepharoptosis, cataract, pterygium, diabetic retinopathy, age-related macular degeneration, glaucoma, dry eye disease, and color vision deficiency. The measurements included in the ophthalmic questionnaire and examination methods were modified in the KNHANES IV, V, and VI. In this article, we provide detailed information about the methodology of the ophthalmic examinations in KNHANES in order to aid in further investigations related to major eye diseases in South Korea.

  1. Cost-effectiveness analysis of clinic-based chloral hydrate sedation versus general anaesthesia for paediatric ophthalmological procedures.

    Science.gov (United States)

    Burnett, Heather F; Lambley, Rosemary; West, Stephanie K; Ungar, Wendy J; Mireskandari, Kamiar

    2015-11-01

    The inability of some children to tolerate detailed eye examinations often necessitates general anaesthesia (GA). The objective was to assess the incremental cost effectiveness of paediatric eye examinations carried out in an outpatient sedation unit compared with GA. An episode of care cost-effectiveness analysis was conducted from a societal perspective. Model inputs were based on a retrospective cross-over cohort of Canadian children aged 68 successful procedures per child. The result was robust to varying the cost assumptions. Cross-over designs offer a powerful way to assess costs and effectiveness of two interventions because patients serve as their own control. This study demonstrated significant savings when ophthalmological exams were carried out in a hospital outpatient clinic, although with slightly fewer procedures completed. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  2. Improving the Teaching Skills of Residents in a Surgical Training Program: Results of the Pilot Year of a Curricular Initiative in an Ophthalmology Residency Program.

    Science.gov (United States)

    Chee, Yewlin E; Newman, Lori R; Loewenstein, John I; Kloek, Carolyn E

    2015-01-01

    To design and implement a teaching skills curriculum that addressed the needs of an ophthalmology residency training program, to assess the effect of the curriculum, and to present important lessons learned. A teaching skills curriculum was designed for the Harvard Medical School (HMS) Residency Training Program in Ophthalmology. Results of a needs assessment survey were used to guide curriculum objectives. Overall, 3 teaching workshops were conducted between October 2012 and March 2013 that addressed areas of need, including procedural teaching. A postcurriculum survey was used to assess the effect of the curriculum. Massachusetts Eye and Ear Infirmary, a tertiary care institution in Boston, MA. Overall, 24 residents in the HMS Residency Training Program in Ophthalmology were included. The needs assessment survey demonstrated that although most residents anticipated that teaching would be important in their future career, only one-third had prior formal training in teaching. All residents reported they found the teaching workshops to be either very or extremely useful. All residents reported they would like further training in teaching, with most residents requesting additional training in best procedural teaching practices for future sessions. The pilot year of the resident-as-teacher curriculum for the HMS Residency Training Program in Ophthalmology demonstrated a need for this curriculum and was perceived as beneficial by the residents, who reported increased comfort in their teaching skills after attending the workshops. Copyright © 2015 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.

  3. Citation analysis of three ophthalmology journals%三种眼科学期刊引文分析

    Institute of Scientific and Technical Information of China (English)

    杨华; 徐洪斌

    2007-01-01

    目的 探讨中、美、英三国主办的三种眼科学期刊引文的引用规律及情报吸收能力.方法 采用引文计量分析法统计American Journal of Ophthalmology(AJO)、British Journal of Ophthalmology(BJO)与中华眼科杂志(CJO)2005年刊载的论文所引用的参考文献,从引文数量、引文年代、普赖斯指数、自引率、高被引期刊等多方面进行比较分析.结果 AJO、BJO及CJO篇均引文数量分别为12.67、21.31及11.50,AJO、BJO及CJO的普赖斯指数分别为37.12%、33.47%及44.42%,自引率分别为13.39%、7.54%及9.89%,AJO、BJO及CJO分别引用了1140、1487及724种期刊,前13种期刊总被引频次占全部引文的58.82%、49.51%及46.39%.结论 AJO、BJO及CJO各自具有不同的特点.BJO篇均引文数较高,涉猎文献范围广,自引率较低,引用文献半衰期较长;AJO引用期刊相对集中,自引率相对较高;CJO引用文献较新,普赖斯指数较高,自引率适中.

  4. Achados oftalmológicos em pacientes com múltiplas deficiências Ophthalmologic findings in multiple handicapped patients

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    Maria Cecília Remígio

    2006-12-01

    Full Text Available OBJETIVO: Relatar os achados oftalmológicos em portadores de múltiplas deficiências. MÉTODOS: Foram estudados 274 usuários do Sistema Único de Saúde atendidos no Departamento de Oftalmologia Pediátrica e Estrabismo da Fundação Altino Ventura (FAV, no período de junho a setembro de 2004. RESULTADOS: A freqüência dos pacientes quanto ao gênero foi de 58,5% para o masculino e 41,5% para o feminino. A variação das idades foi de 0,1 a 20 anos com mediana de 5. A maioria (61,3% dos pacientes apresentava boa acuidade visual, contudo 38,7% apresentava baixa de visão (PURPOSE: To report the visual findings in patients with multiple handicaps. METHODS: Two hundred and seventy-four patients cared for at the Pediatric and Strabismus Ophthalmology Department of the "Fundação Altino Ventura" - Brazilian National Health System, were examined from June to September 2004. Age varied from 0.1 to 20 years with a median of 5. RESULTS: The majority of the patients (61.3% presented good visual acuity; however low visual acuity (< 20/80 was observed in 38.7% of the patients. Heterotropias were observed in 66 patients (24.0%; astigmatism (53.2% and hyperopia (29.0% were more frequent. CONCLUSION: Children with multiple handicaps need an early ophthalmologic diagnosis and treatment for better global development. The integration of a multidisciplinary team with pediatricians, pediatric ophthalmologists and specialists in low vision, may assure a better visual rehabilitation.

  5. An evaluation of medical college departments of ophthalmology in India and change following provision of modern instrumentation and training

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    Thomas Ravi

    2008-01-01

    Full Text Available Aim: To evaluate teaching and practice in medical college ophthalmology departments in a representative Indian state and changes following provision of modern instrumentation and training. Study Type: Prospective qualitative study. Materials and Methods: Teaching and practice in all medical colleges in the state assessed on two separate occasions by external evaluators. Preferred criteria for training and care were pre-specified. Methodology included site visits to document functioning and conduct interviews. Assessments included resident teaching, use of instrumentation provided specifically for training and standard of eye care. The first evaluation (1998 was followed by provision of modern instrumentation and training on two separate occasions, estimated at Rupees 34 crores. The follow-up evaluation in 2006 used the same methodology as the first. Results: Eight departments were evaluated on the first occasion; there were 11 at the second. On the first assessment, none of the programs met the criteria for training or care. Following the provision of modern instrumentation and training, intraocular lens usage increased dramatically; but the overall situation remained essentially unchanged in the 8 departments evaluated 8 years later. Routine comprehensive eye examination was neither taught nor practiced. Individually supervised surgical training using beam splitters was not practiced in any program; neither was modern management of complications or its teaching. Phacoemulsification was not taught, and residents were not confident of setting up practice. Instruments provided specifically for training were not used for that purpose. Students reported that theoretical teaching was good. Conclusions: Drastic changes in training, patient care and accountability are needed in most medical college ophthalmology departments.

  6. Localised treatment and 6-month outcomes in patients with cytomegalovirus retinitis at a tertiary ophthalmology service in Ga-Rankuwa

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    Fatima Laher

    2012-06-01

    Full Text Available Objective. There are few data from before the antiretroviral therapy (ART era for cytomegalovirus retinitis (CMV-R from settings where cost limits use of systemic treatment. This study examines CMV-R treatment and survival outcomes in a public hospital ophthalmology service in Ga-Rankuwa, South Africa. Methods. From October 2009 to October 2010, voluntarily consenting participants over the age of 15 years with incident clinically diagnosed CMV-R seen at the Dr George Mukhari Hospital ophthalmology clinic were prospectively enrolled in an observational study. Treatment was per clinic protocols and patients were followed up with structured data collection for up to 6 months. Results. Eight individuals, all HIV infected and 50% female, were identified and enrolled. At enrolment, median age was 38 years (interquartile range (IQR 32 - 39 years, median CD4 count 20 cells/μl (IQR 13 - 46.5 cells/μl, and 50% were currently receiving ART (mean duration of ART use 18 days, standard deviation (SD 2.99 days. No participant received systemic ganciclovir, but 6 reported symptom combinations suggesting systemic CMV: shortness of breath (n=3, diarrhoea (n=3 and/or central nervous system complaints (n=3. Ten eyes had visual impairment less than counting fingers at enrolment. Treatment combinations were: ART plus intravitreal ganciclovir (n=5, intravitreal ganciclovir alone (n=2, and ART alone (n=1. Six-month outcomes were: death (n=1, survival (n=6, loss to follow-up (n=3, untraceable (n=1, systemic symptom resolution (4/4, visual acuity deterioration (0/5, and persisting uveitis (2/3. Conclusion. In the ART era, incident CMV-R appears to be uncommon in this setting. CMV-R may occur within the first 3 weeks after ART initiation. Even in CMV-R patients with suggestive systemic symptoms, 6-month survival is good despite no systemic CMV therapy. S Afr J HIV Med 2012;13(2:68-71.

  7. SacLab: A toolbox for saccade analysis to increase usability of eye tracking systems in clinical ophthalmology practice.

    Science.gov (United States)

    Cercenelli, Laura; Tiberi, Guido; Corazza, Ivan; Giannaccare, Giuseppe; Fresina, Michela; Marcelli, Emanuela

    2017-01-01

    Many open source software packages have been recently developed to expand the usability of eye tracking systems to study oculomotor behavior, but none of these is specifically designed to encompass all the main functions required for creating eye tracking tests and for providing the automatic analysis of saccadic eye movements. The aim of this study is to introduce SacLab, an intuitive, freely-available MATLAB toolbox based on Graphical User Interfaces (GUIs) that we have developed to increase the usability of the ViewPoint EyeTracker (Arrington Research, Scottsdale, AZ, USA) in clinical ophthalmology practice. SacLab consists of four processing modules that enable the user to easily create visual stimuli tests (Test Designer), record saccadic eye movements (Data Recorder), analyze the recorded data to automatically extract saccadic parameters of clinical interest (Data Analyzer) and provide an aggregate analysis from multiple eye movements recordings (Saccade Analyzer), without requiring any programming effort by the user. A demo application of SacLab to carry out eye tracking tests for the analysis of horizontal saccades was reported. We tested the usability of SacLab toolbox with three ophthalmologists who had no programming experience; the ophthalmologists were briefly trained in the use of SacLab GUIs and were asked to perform the demo application. The toolbox gained an enthusiastic feedback from all the clinicians in terms of intuitiveness, ease of use and flexibility. Test creation and data processing were accomplished in 52±21s and 46±19s, respectively, using the SacLab GUIs. SacLab may represent a useful tool to ease the application of the ViewPoint EyeTracker system in clinical routine in ophthalmology. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. On textual and contextual position of the ophthalmological treatise of bodhisattva nāgārjuna.

    Science.gov (United States)

    Kim, Seongsu; Kang, Sungyong

    2013-04-01

    Medical knowledge in India began to be introduced to China in earliest from the Later Han Dynasty period to the times of Wei-Qin and South & North Dynasties. This is proved by many Buddhist medical books appeared in those days. Of the contents of Indian medicine, the theory of four major elements affected Chinese medicine more than did the theory of body fluids. Based on the theory of four major elements that was began to be introduced in Fú shuō fú yī jīng, an attempt to establish a new medical system was made in Zhŏu hòu băi yīfāng written by Táo Hóng-jĭng and Sūn Sī-miăo who tried to develop etiology further but could not achieve any great outcomes. Unlike the foregoing situation, Indian medicine aroused a large echo in China in the field of ophthalmology with ophthalmological knowledge mentioned in Suśrutasa hitā and 'Jīnzhēn-shù'(cataract couching) introduced as a surgical treatment of cataract. The Suśrutasa hitā which is one of the three major texts of Indian medicine contains additional information on surgical operations not introduced in the Carakasa hitā. The technique of cataract surgery was particularly popular in the Tang and Song dynasty periods in China under the name Lóng shù pú sà yăn lùn(The Ophthalmological Treatise of Bodhisattva Nāgārjuna) or Lóng shù lùn and was even designated as a subject to educate medical officers. While the original text of Lóng shù pú sà yăn lùn was not handed down, the first testimony that show the trace of the introduction of this text into China was the Tiān zhú jīng lùn yăn mentioned in Wài tái mì yào(Arcane Essential from the Imperial Library) written by Wang Tao. Long shàng dào ren who was mentioned as the compiler of the book is assumed to be Lóng shù. Although Tiān zhú jīng lùn yăn introduced anatomical knowledge about the eyeball that could have not been in the traditional Chinese medicine, this book has only limited quantity of information in this

  9. Patología orbitocraneana de presentación oftalmológica Orbitocranial pathology with ophthalmologic symptoms

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    Silvina De Luca

    2012-06-01

    ón de estudios por imágenes en la evaluación de las principales entidades neuro-oftalmológicas que se presentan con signos y síntomas oculares nos permiten arribar a un diagnóstico temprano y, como consecuencia, a la implementación del tratamiento indicado.Objectives. To report the clinical and etiological correlation of different orbitocranial lesions in patients initially presenting with ophthalmologic symptoms and to determine its contribution to the selection of the diagnostic test of choice for each individual case. Materials and Methods. We have evaluated retrospectively 36 patients with orbital and/or intracranial conditions, who presented at the ophthalmology department of our institution between july 2007 and january 2011. All patients underwent an ophthalmologic examination, computerassisted campimetry, multislice computed tomography (MSCT, magnetic resonance imaging (MRI and some had a histopathological test performed. Results. The most common initial symptom was decreased or impaired visual acuity, present in 22 patients (61%. Others symptoms were diplopia in 9 patients (25%, exophthalmos in 2 (5.5%, orbital hematoma in 2 (5.5% and leukocoria in 1 (3%. In the group of patients with visual impairments, the etiological diagnoses were diverse and included: sphenoid meningioma (n=4, Devic's disease (n=2, brainstem glioma (n=1, optic glioma in the context of type 1 neurofibromatosis (n=1, metastasis of breast carcinoma (n= 4, brain lymphoma (n=2, stroke (n=4, lymphocytic hypophysitis (n=1 and pseudotumor cerebri (n=2. In patients with diplopia diagnosis included: a quadrigeminal plate tumor, one pineal cyst with acute hydrocephalus, two posterior communicating artery aneurysms, two intracavernous internal carotid artery aneurysms (one of them giant and dissecting, one ventral supraclinoid internal carotid artery aneurysm and two fronto-ethmoidal mucoceles. We highlight the presence of two optic nerve meningiomas initially presented with exophthalmos and

  10. An Analysis of Peer-Reviewed Scores and Impact Factors with Different Citation Time Windows: A Case Study of 28 Ophthalmologic Journals.

    Science.gov (United States)

    Liu, Xue-Li; Gai, Shuang-Shuang; Zhang, Shi-Le; Wang, Pu

    2015-01-01

    An important attribute of the traditional impact factor was the controversial 2-year citation window. So far, several scholars have proposed using different citation time windows for evaluating journals. However, there is no confirmation whether a longer citation time window would be better. How did the journal evaluation effects of 3IF, 4IF, and 6IF comparing with 2IF and 5IF? In order to understand these questions, we made a comparative study of impact factors with different citation time windows with the peer-reviewed scores of ophthalmologic journals indexed by Science Citation Index Expanded (SCIE) database. The peer-reviewed scores of 28 ophthalmologic journals were obtained through a self-designed survey questionnaire. Impact factors with different citation time windows (including 2IF, 3IF, 4IF, 5IF, and 6IF) of 28 ophthalmologic journals were computed and compared in accordance with each impact factor's definition and formula, using the citation analysis function of the Web of Science (WoS) database. An analysis of the correlation between impact factors with different citation time windows and peer-reviewed scores was carried out. Although impact factor values with different citation time windows were different, there was a high level of correlation between them when it came to evaluating journals. In the current study, for ophthalmologic journals' impact factors with different time windows in 2013, 3IF and 4IF seemed the ideal ranges for comparison, when assessed in relation to peer-reviewed scores. In addition, the 3-year and 4-year windows were quite consistent with the cited peak age of documents published by ophthalmologic journals. Our study is based on ophthalmology journals and we only analyze the impact factors with different citation time window in 2013, so it has yet to be ascertained whether other disciplines (especially those with a later cited peak) or other years would follow the same or similar patterns. We designed the survey questionnaire

  11. Extracapsular cataract extraction training: junior ophthalmology residents' self-reported satisfaction level with their proficiency and initial learning barrier.

    Science.gov (United States)

    Ting, Daniel Shu Wei; Tan, Sarah; Lee, Shu Yen; Rosman, Mohamad; Aw, Ai Tee; Yeo, Ian Yew San

    2015-07-01

    To investigate residents' self-reported satisfaction level with their proficiency in extracapsular cataract extraction (ECCE) surgery and the initial barriers to learning the procedure. This is a single-centre prospective descriptive case series involving eight first-year ophthalmology residents in Singapore National Eye Center. We recorded the demographics, frequency of review by the residents of their own surgical videos and their satisfaction level with their proficiency at each of the ECCE steps using a 5-point Likert scale. All ECCE surgical videos between October 2013 and May 2014 were collected and analysed for the overall time taken for the surgery and the time taken to perform the individual steps of the procedure. The mean age of the residents was 27.6 ± 1.5 years and 62.5% (5/8) were women. More than half (62.5%, 5/8) reviewed their own surgical videos while 37.5% (3/8) discussed the surgical videos with their peers or supervisors. Of the ECCE steps, the residents were most dissatisfied with their proficiency in performing irrigation and aspiration (87.5%, 7/8), followed by suturing (62.5%, 5/8), intraocular lens insertion (62.5%, 5/8) and tin can capsulotomy (62.5%, 5/8). The average time taken for each ECCE case was 55.0 ± 12.2 min and, of all the steps, most time was spent on suturing (20.5 ± 6.8 min), followed by irrigation and aspiration (5.5 ± 3.6 min) and tin can capsulotomy (3.3 ± 1.8 min). The first-year ophthalmology residents were most dissatisfied with their proficiency in irrigation/aspiration, suturing and tin can capsulotomy. More training needs to be directed to these areas during teaching sessions in the operating room, wet laboratory or cataract simulation training sessions. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  12. Ophthalmology Anatomy tShijingshan Hospital, Capital Medical University, Beijing 100043eaching%眼科学解剖基础教学

    Institute of Scientific and Technical Information of China (English)

    吴葛玮; 关莹

    2014-01-01

    眼科解剖学教学是眼科的重要基础,但是眼科局部解剖精细复杂,检查设备特殊,具有讲解困难,学生难以理解的特点。笔者根据眼科教学要求,采用多种方式相结合的教学方法,取得了较好的效果。%The elaborate and complex anatomy of eye characterized by strong professional,the eye examination must be of special equipment,coupled with dif icult of teaching,al have made it dif icult to ophthalmology education.Based on the teaching require of our col ege,we used multiple teaching methods of ophthalmology and got ef ective result.

  13. An observational study of the proceedings of the All India Ophthalmological Conference, 2000 and subsequent publication in indexed journals

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    Dhaliwal Upreet

    2008-01-01

    Full Text Available Aims: To determine the quality of reporting in the proceedings of the All India Ophthalmological Conference (AIOC 2000, subsequent rate of publication in an indexed journal and differences between the proceedings and the journal version of these papers. Design: Observational study. Materials and Methods: All papers presented at the AIOC 2000 were retrieved from the proceedings and assessed for completeness of reporting. To determine the subsequent full publication, a Medline search was performed as of January 2007; consistency between the proceedings paper and the final publication was evaluated. Statistical analysis: Chi square and Fisher′s exact tests were used to compare publication rates based on geographical location, subspecialty and study design; Student′s t -test was used to compare differences based on the number of authors and sample size. Results: Two hundred papers were retrieved; many failed to include study dates, design or statistical methods employed. Thirty-three (16.5% papers were subsequently published in indexed journals by January 2007. The published version differed from the proceedings paper in 27 (81.8% instances, mostly relating to changes in author name, number or sequence. Conclusions: The overall quality of reporting of scientific papers in the proceedings of the AIOC 2000 was inadequate and many did not result in publication in an indexed journal. Differences between the published paper in journals and in proceedings were seen in several instances. Ophthalmologists should be cautious about using the information provided in conference proceedings in their ophthalmic practice.

  14. Anti-vascular endothelial growth factor pharmacotherapy for diabetic macular edema: a report by the American Academy of Ophthalmology.

    Science.gov (United States)

    Ho, Allen C; Scott, Ingrid U; Kim, Stephen J; Brown, Gary C; Brown, Melissa M; Ip, Michael S; Recchia, Franco M

    2012-10-01

    To review the evidence regarding the safety and efficacy of current anti-vascular endothelial growth factor (VEGF) pharmacotherapies for the treatment of diabetic macular edema (DME). Literature searches last were conducted in September 2011, in PubMed with no date restrictions, limited to articles published in English, and in the Cochrane Library without a language limitation. The combined searches yielded 532 citations, of which 45 were deemed clinically relevant for the authors to review in full text and to assign ratings of level of evidence to each of the selected studies with the guidance of the panel methodologists. At this time, there are 5 studies that provide level I evidence for intravitreal ranibizumab, alone or in combination with other treatments for DME. There is also 1 study that provides level I evidence for intravitreal pegaptanib sodium for DME. Nine studies reviewed were rated as level II, and 2 additional studies reviewed were graded as level III. Most studies do not provide information about long-term results (i.e., more than 2 years of follow-up) or the comparative efficacy of anti-VEGF pharmacotherapies. Review of the available literature indicates that anti-VEGF pharmacotherapy, delivered by intravitreal injection, is a safe and effective treatment over 2 years for DME. Further evidence is required to support the long-term safety of these pharmacotherapies and their comparative efficacy. Copyright © 2012 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  15. Therapeutic use of contact lenses in ophthalmology%治疗性接触镜的规范应用

    Institute of Scientific and Technical Information of China (English)

    钟兴武

    2013-01-01

    Soft therapeutic contact lenses are widely used in clinical ophthalmology to protect the ocular surface and treat eye diseases or as an adjuvant therapy with the development of materials,design and processing.The purpose of this article is to further normalize the application of therapeutic contact lenses by introducing their indications,contraindications and principles of choice and fitting in detail with the goal of providing better service.%随着接触镜材料、设计和加工工艺的进步,软性治疗性接触镜已广泛应用于保护眼表、治疗或辅助治疗某些眼病.笔者详细介绍治疗性接触镜的适应证、禁忌证、镜片选择和配戴要点,进一步规范应用治疗性接触镜,更好地为眼科临床服务.

  16. [Retinotopic mapping of the human visual cortex with functional magnetic resonance imaging - basic principles, current developments and ophthalmological perspectives].

    Science.gov (United States)

    Hoffmann, M B; Kaule, F; Grzeschik, R; Behrens-Baumann, W; Wolynski, B

    2011-07-01

    Since its initial introduction in the mid-1990 s, retinotopic mapping of the human visual cortex, based on functional magnetic resonance imaging (fMRI), has contributed greatly to our understanding of the human visual system. Multiple cortical visual field representations have been demonstrated and thus numerous visual areas identified. The organisation of specific areas has been detailed and the impact of pathophysiologies of the visual system on the cortical organisation uncovered. These results are based on investigations at a magnetic field strength of 3 Tesla or less. In a field-strength comparison between 3 and 7 Tesla, it was demonstrated that retinotopic mapping benefits from a magnetic field strength of 7 Tesla. Specifically, the visual areas can be mapped with high spatial resolution for a detailed analysis of the visual field maps. Applications of fMRI-based retinotopic mapping in ophthalmological research hold promise to further our understanding of plasticity in the human visual cortex. This is highlighted by pioneering studies in patients with macular dysfunction or misrouted optic nerves.

  17. The Long-Term Financial and Clinical Impact of an Electronic Health Record on an Academic Ophthalmology Practice

    Directory of Open Access Journals (Sweden)

    Michele C. Lim

    2015-01-01

    Full Text Available Purpose. To examine financial and clinical work productivity outcomes associated with the use of the electronic health record (EHR. Methods. 191,360 billable clinical encounters were analyzed for 12 clinical providers over a 9-year study period during which an EHR was implemented. Main outcome measures were clinical revenues collected per provider and secondary outcomes were charge capture, patient visit coding levels, transcription costs, patient visit volume per provider, digital drawing, and digital imaging volume. Results. The difference in inflation adjusted net clinical revenue per provider per year did not change significantly in the period after EHR implementation (mean = $404,198; SD = $17,912 than before (mean = $411,420; SD = $39,366 (P=0.746. Charge capture, the proportion of higher- and lower-level visit codes for new and established patients, and patient visits per provider remained stable. A total savings of $188,951 in transcription costs occurred over a 4-year time period post-EHR implementation. The rate of drawing the ophthalmic exam in the EHR was low (mean = 2.28%; SD = 0.05% for all providers. Conclusions. This study did not show a clear financial gain after EHR implementation in an academic ophthalmology practice. Ophthalmologists do not rely on drawings to document the ophthalmic exam; instead, the ophthalmic exam becomes text-driven in a paperless world.

  18. Quality of life in chemical warfare survivors with ophthalmologic injuries: the first results form Iran Chemical Warfare Victims Health Assessment Study

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    Soroush Mohammad

    2009-01-01

    Full Text Available Abstract Background Iraq used chemical weapons extensively against the Iranians during the Iran-Iraq war (1980–1988. The aim of this study was to assess the health related quality of life (HRQOL in people who had ophthalmologic complications due to the sulfur mustard gas exposure during the war. Methods The Veterans and Martyrs Affair Foundation (VMAF database indicated that there were 196 patients with severe ophthalmologic complications due to chemical weapons exposure. Of these, those who gave consent (n = 147 entered into the study. Quality of life was measured using the 36-item Short Form Health Survey (SF-36 and scores were compared to those of the general public. In addition logistic regression analysis was performed to indicate variables that contribute to physical and mental health related quality of life. Results The mean age of the patients was 44.8 (SD = 8.7 ranging from 21 to 75 years. About one-third of the cases (n= 50 reported exposure to chemical weapons more than once. The mean exposure duration to sulfur mustard gas was 21.6 years (SD = 1.2. The lowest scores on the SF-36 subscales were found to be: the role physical and the general health. Quality of life in chemical warfare victims who had ophthalmologic problems was significantly lower than the general public (P Conclusion The study findings suggest that chemical warfare victims with ophthalmologic complications suffer from poor health related quality of life. It seems that the need for provision of health and support for this population is urgent. In addition, further research is necessary to measure health related quality of life in victims with different types of disabilities in order to support and enhance quality of life among this population.

  19. Stem Cell Ophthalmology Treatment Study (SCOTS: bone marrow-derived stem cells in the treatment of Leber′s hereditary optic neuropathy

    Directory of Open Access Journals (Sweden)

    Jeffrey N Weiss

    2016-01-01

    Full Text Available The Stem Cell Ophthalmology Treatment Study (SCOTS is currently the largest-scale stem cell ophthalmology trial registered at ClinicalTrials.gov (identifier: NCT01920867. SCOTS utilizes autologous bone marrow-derived stem cells (BMSCs to treat optic nerve and retinal diseases. Treatment approaches include a combination of retrobulbar, subtenon, intravitreal, intra-optic nerve, subretinal, and intravenous injection of autologous BMSCs according to the nature of the disease, the degree of visual loss, and any risk factors related to the treatments. Patients with Leber′s hereditary optic neuropathy had visual acuity gains on the Early Treatment Diabetic Retinopathy Study (ETDRS of up to 35 letters and Snellen acuity improvements from hand motion to 20/200 and from counting fingers to 20/100. Visual field improvements were noted. Macular and optic nerve head nerve fiber layer typically thickened. No serious complications were seen. The increases in visual acuity obtained in our study were encouraging and suggest that the use of autologous BMSCs as provided in SCOTS for ophthalmologic mitochondrial diseases including Leber′s hereditary optic neuropathy may be a viable treatment option.

  20. Discussion on Humanistic Nursing Skills in Elderly Patients of Ophthalmology%眼科老年患者的人性化护理技巧探讨

    Institute of Scientific and Technical Information of China (English)

    王娜娜; 詹江波; 张郧芳

    2012-01-01

    目的 探讨针对眼科老年患者的人性化护理技巧.方法 坚持以病人为中心,护理人员掌握好老年患者的心理特征,转变服务观念,规范护理行为;灵活运用沟通技巧,加强护患沟通工作.结果 住院患者的安全得到保证,护理缺陷和护理纠纷减少.结论 有针对性的人性化护理是保证眼科患者医疗安全、减少护理缺陷和防范护理纠纷的一项重要措施.%Objective;To explore the humanistic nursing skills in elderly patients of ophthalmology. Method; Taking the patients as the center, the nursing staff grasps the psychological characteristics of elderly patients of ophthalmology, changes the service concepts and standardizes the nursing behavior, flexibly uses the communication skills and strengthens the communication. Result; The nursing safe of the patients was ensured, the nursing defects and nursing disputes were decreased. Conclusion; Targeted humanistic nursing skills is an important measure for the elderly patients of ophthalmology to ensure the medical safety, reduce nursing defects and prevent nursing disputes.

  1. Stem Cell Ophthalmology Treatment Study (SCOTS):bone marrow-derived stem cells in the treatment of Leber’s hereditary optic neuropathy

    Institute of Scientific and Technical Information of China (English)

    Jeffrey N Weiss; Steven Levy; Susan C Benes

    2016-01-01

    hTe Stem Cell Ophthalmology Treatment Study (SCOTS) is currently the largest-scale stem cell ophthal-mology trial registered at ClinicalTrials.gov (identiifer: NCT01920867). SCOTS utilizes autologous bone marrow-derived stem cells (BMSCs) to treat optic nerve and retinal diseases. Treatment approaches include a combination of retrobulbar, subtenon, intravitreal, intra-optic nerve, subretinal, and intravenous injection of autologous BMSCs according to the nature of the disease, the degree of visual loss, and any risk factors related to the treatments. Patients with Leber’s hereditary optic neuropathy had visual acuity gains on the Early Treatment Diabetic Retinopathy Study (ETDRS) of up to 35 letters and Snellen acuity improvements from hand motion to 20/200 and from counting ifngers to 20/100. Visual ifeld improvements were noted. Macular and optic nerve head nerve ifber layer typically thickened. No serious complications were seen. hTe increases in visual acuity obtained in our study were encouraging and suggest that the use of autolo-gous BMSCs as provided in SCOTS for ophthalmologic mitochondrial diseases including Leber’s hereditary optic neuropathy may be a viable treatment option.

  2. Epidemiologic Evaluation of Ocular Trauma in Patients Admitted to Ophthalmology Ward of Farshchian Hospital in Hamadan in 2012

    Directory of Open Access Journals (Sweden)

    N. Bazzazi

    2014-04-01

    Full Text Available Introduction & Objective: Ocular trauma is one of the important reasons of visual loss which can cause multiple damages to eyelid, eyeball and adenexal tissues. Furthermore, ocular trauma is one of the major causes of unilateral blindness and the third leading cause of hospi-talization in ophthalmology wards. The aim of this study is to determine the prevalence and characteristics of eye trauma at Farshchian hospital in Hamadan in 2012. Material & Methods: In this cross-sectional descriptive study, 70 patients with ocular trauma, admitted to Farshchian hospital, were studied. We assessed the age, sex, job , educational level, location, cause of trauma, its type and site of injury. The data was analyzed by SPSS 16 software and t, ?2 statistical tests. Results: The mean age of patients in this study was 24.01 years (SD= 16.04. Among 70 pa-tients, 58 people (82.1% were males and 12 patients (17.1% were females. The most com-mon cause of trauma was observed in 19 patients (27.1%. The most common location of the trauma in this study was homing, seen in 28 patients (40%. Among the 70 patients, 29 peo-ple (41.4% had open globe injuries, 25 people had (35.7% closed globe injuries, 5 patients (7.1% had burning and 11 patients (15.7% had adenexal injury. Conclusions: The results showed that most ocular traumas occur in the early ages and in males. The most common type of them is open globe injury and the most common cause is a sharp object. (Sci J Hamadan Univ Med Sci 2014; 21 (1:25-31

  3. CHARACTERIZATION OF ANTERIOR SEGMENT OPHTHALMOLOGIC LESIONS IDENTIFIED IN FREE-RANGING DOLPHINS AND THOSE UNDER HUMAN CARE.

    Science.gov (United States)

    Colitz, Carmen M H; Walsh, Michael T; McCulloch, Stephen D

    2016-03-01

    Cetaceans in the wild and under human care develop a variety of ocular lesions. Although they have echolocation, cetacean species have good sight, making ocular health an important part of overall health care. The cornea is the primary site of abnormalities in both populations. Typical lesions of cetaceans under human care are characterized in this retrospective review of cases. One hundred eighty animals (n = 360 eyes) were chosen from the author's ophthalmologic examination reports from different geographic areas; they included Atlantic bottlenose dolphins (Tursiops truncatus), Pacific bottle nose dolphins (Tursiopstruncatus gilli), Indopacific bottlenose dolphins (Steno bredanensis), Indopacific humpback dolphins (Sousa chinensis), and roughtooth dolphins (Steno bredanensis). These animals were examined at least once, although most were examined numerous times over many years; lesions were categorized and are described. Seventy-seven eyes from 47 animals were normal. Medial keratopathy was the most common lesion and identified in 180 eyes from 97 animals, with 83 affected bilaterally. Horizontal keratopathy was identified in 69 eyes from 41 animals, with 28 affected bilaterally. Axial keratopathy and nonspecific axial opacities were identified in 67 eyes from 44 animals, with 21 affected bilaterally. Seventy-eight eyes from 50 animals, with 28 affected bilaterally, had more than one type of corneal lesion. Cataracts were identified in 32 eyes from 19 animals, with 13 affected bilaterally. Traumatic injuries were also common and involved eyelids and cornea. Sixteen eyes from 11 animals were blind; five dolphins were blind bilaterally due to phthisis bulbi secondary to corneal perforation or severe trauma. None of the diseases had a sex predisposition; however, medial keratopathy was significantly more common as a bilateral presentation than as a unilateral presentation. Cetaceans under human care with impaired sight can use echolocation; however, ocular health

  4. Impact of an electronic health record operating room management system in ophthalmology on documentation time, surgical volume, and staffing.

    Science.gov (United States)

    Sanders, David S; Read-Brown, Sarah; Tu, Daniel C; Lambert, William E; Choi, Dongseok; Almario, Bella M; Yackel, Thomas R; Brown, Anna S; Chiang, Michael F

    2014-05-01

    Although electronic health record (EHR) systems have potential benefits, such as improved safety and quality of care, most ophthalmology practices in the United States have not adopted these systems. Concerns persist regarding potential negative impacts on clinical workflow. In particular, the impact of EHR operating room (OR) management systems on clinical efficiency in the ophthalmic surgery setting is unknown. To determine the impact of an EHR OR management system on intraoperative nursing documentation time, surgical volume, and staffing requirements. For documentation time and circulating nurses per procedure, a prospective cohort design was used between January 10, 2012, and January 10, 2013. For surgical volume and overall staffing requirements, a case series design was used between January 29, 2011, and January 28, 2013. This study involved ophthalmic OR nurses (n = 13) and surgeons (n = 25) at an academic medical center. Electronic health record OR management system implementation. (1) Documentation time (percentage of operating time documenting [POTD], absolute documentation time in minutes), (2) surgical volume (procedures/time), and (3) staffing requirements (full-time equivalents, circulating nurses/procedure). Outcomes were measured during a baseline period when paper documentation was used and during the early (first 3 months) and late (4-12 months) periods after EHR implementation. There was a worsening in total POTD in the early EHR period (83%) vs paper baseline (41%) (P system implementation was associated with worsening of intraoperative nursing documentation time especially in shorter procedures. However, it is possible to implement an EHR OR management system without serious negative impacts on surgical volume and staffing requirements.

  5. Generic medications in ophthalmology.

    Science.gov (United States)

    Zore, Matt; Harris, Alon; Tobe, Leslie Abrams; Siesky, Brent; Januleviciene, Ingrida; Behzadi, Jennifer; Amireskandari, Annahita; Egan, Patrick; Garff, Kevin; Wirostko, Barbara

    2013-03-01

    The purpose of this review is to discuss the process of genericisation of medications in the US and Europe with a focus on ophthalmic drugs. Regulatory guidelines of the US Food and Drug Administration and the European Medicines Agency will be discussed, and the advantages and concerns of genericisation will be explored. We will look at various studies concerning the safety and efficacy of generic drugs compared to their branded counterparts. In particular, the challenges of assuring bioequivalence and therapeutic equivalence in topical ophthalmic drugs will be examined.

  6. [Adaptive optics for ophthalmology].

    Science.gov (United States)

    Saleh, M

    2016-04-01

    Adaptive optics is a technology enhancing the visual performance of an optical system by correcting its optical aberrations. Adaptive optics have already enabled several breakthroughs in the field of visual sciences, such as improvement of visual acuity in normal and diseased eyes beyond physiologic limits, and the correction of presbyopia. Adaptive optics technology also provides high-resolution, in vivo imaging of the retina that may eventually help to detect the onset of retinal conditions at an early stage and provide better assessment of treatment efficacy.

  7. Smartphones in ophthalmology

    Directory of Open Access Journals (Sweden)

    Jay Chhablani

    2012-01-01

    Full Text Available The potential usefulness of smartphones in the medical field is evolving everyday. This article describes various tools available on smartphones, largely focusing on the iPhone, for the examination of an ophthalmic patient, for patient and physician education, as well as reference tools for both ophthalmologists and vision researchers. Furthermore, the present article discusses how smartphones can be used for ophthalmic photography and image management, and foremost, the usefulness of the applications such as the Eye Handbook for the ophthalmologist and interested students, patients, physicians, and researchers, currently available in the iPhone.

  8. Wavefront Measurement in Ophthalmology

    Science.gov (United States)

    Molebny, Vasyl

    Wavefront sensing or aberration measurement in the eye is a key problem in refractive surgery and vision correction with laser. The accuracy of these measurements is critical for the outcome of the surgery. Practically all clinical methods use laser as a source of light. To better understand the background, we analyze the pre-laser techniques developed over centuries. They allowed new discoveries of the nature of the optical system of the eye, and many served as prototypes for laser-based wavefront sensing technologies. Hartmann's test was strengthened by Platt's lenslet matrix and the CCD two-dimensional photodetector acquired a new life as a Hartmann-Shack sensor in Heidelberg. Tscherning's aberroscope, invented in France, was transformed into a laser device known as a Dresden aberrometer, having seen its reincarnation in Germany with Seiler's help. The clinical ray tracing technique was brought to life by Molebny in Ukraine, and skiascopy was created by Fujieda in Japan. With the maturation of these technologies, new demands now arise for their wider implementation in optometry and vision correction with customized contact and intraocular lenses.

  9. Adaptive ophthalmologic system

    Science.gov (United States)

    Olivier, Scot S.; Thompson, Charles A.; Bauman, Brian J.; Jones, Steve M.; Gavel, Don T.; Awwal, Abdul A.; Eisenbies, Stephen K.; Haney, Steven J.

    2007-03-27

    A system for improving vision that can diagnose monochromatic aberrations within a subject's eyes, apply the wavefront correction, and then enable the patient to view the results of the correction. The system utilizes a laser for producing a beam of light; a corrector; a wavefront sensor; a testing unit; an optic device for directing the beam of light to the corrector, to the retina, from the retina to the wavefront sensor, and to the testing unit; and a computer operatively connected to the wavefront sensor and the corrector.

  10. Comparing the preventive effect of 2 percent Topical Lidocaine and Intravenous Atropine on oculocardiac reflex in Ophthalmological Surgeries under General Anesthesia

    Directory of Open Access Journals (Sweden)

    Parvin Sajedi

    2013-01-01

    Full Text Available Background: The current study aimed to determine preventive effect of 2 percent topical xylocaine on oculocardiac reflex in ophthalmological surgeries except strabismus, including retinal detachment and vitrectomy with scleral buckling under general anesthesia. Methods: A randomized controlled clinical trial was carried out on 150 patients aged 18-90 years undergoing ophthalmological surgeries under general anesthesia. Samples randomly divided into the experimental group (received four drops of 2 percent topical xylocaine instilled in desired eye and control group (received 0.5 mg atropine sulfate injection. Systolic, diastolic and mean arterial blood pressure of patients and baseline heart rate were recorded. They were compared regarding the incidence of bradycardia, heart rate less than 60 beats/minute, hypotension and blood pressure less than 90 mm/Hg. Data were analyzed by Statistical Package for the Social Sciences software version 20 using Chi-square and ANOVA. Results: The difference between two groups was not statistically significant regarding demographic and basic variables. The incidence of bradycardia in both groups was respectively (90.7 percent vs. 17.3 percent, heart rate less than 60 beats/minute (40 percent vs. 13.3 percent, hypotension (76 percent vs. 32 percent and blood pressure less than 90 mmHg was (28 percent vs. 8 percent. Accordingly, the differences between both groups were statistically significant (P > 0.001. Conclusions: The preventive impact of topical xylocaine upon oculocardiac reflex in ophthalmological surgeries such as retinal detachment and vitrectomy with scleral buckling under general anesthesia was less effective than that of atropine injection. Therefore, to avoid this reflex in high-risk patients, injecting atropine would be safer.

  11. [The stele of the eye doctor in the Museum of Bar and the logo of the French Language Society for the History of Ophthalmology].

    Science.gov (United States)

    Raspiller, A

    2015-02-01

    The objectives are to: recall the circumstances of discovery of two corner pillars 45 years apart and other objects belonging to a circa second century Gallo-Roman temple; analyze the sculptures, of which the best known is the "stele of the eye doctor", which the French Language Society for the History of Ophthalmology took as inspiration for its logo; discuss the significance of instruments and procedures within a markedly religious context at a time when the mystery cults appeared; provide elements for discussion on the interpretation of the scenes depicted on the two pillars.

  12. Development of a new valid, reliable, and internationally applicable assessment tool of residents' competence in ophthalmic surgery (an American Ophthalmological Society thesis).

    Science.gov (United States)

    Golnik, C; Beaver, Hilary; Gauba, Vinod; Lee, Andrew G; Mayorga, Eduardo; Palis, Gabriela; Saleh, George M

    2013-09-01

    To test the validity and reliability of a new tool for assessing residents' competence in ophthalmic surgery. Changing paradigms of ophthalmic education in the United States have influenced worldwide ophthalmic education and necessitated new methods of assessing resident competence. Accordingly, a new tool for assessing residents' competence in ophthalmic surgery (phacoemulsification) that could be applicable internationally was developed. We hypothesize that this instrument is valid and reliable. A panel of six international content experts adapted a previously published tool for assessing phacoemulsification. The tool (called the International Council of Ophthalmology's Ophthalmology Surgical Competency Assessment Rubric, or ICO-OSCAR:phaco) was reviewed by 12 international content experts for their constructive comments, which were incorporated to ensure content validity. Ten expert cataract surgery teachers then graded six recorded phacoemulsification surgeries with the ICO-OSCAR:phaco to investigate inter-rater reliability. The coefficient alpha statistic (a measure of reliability/internal consistency) for the ICO-OSCAR:phaco as a whole was 0.92, and 17 of its 20 dimensions had alpha coefficients greater than 0.70. The ICO-OSCAR:phaco is a valid and reliable assessment tool that could be applied internationally to satisfy the global need of new instruments to comply with emerging trends in ophthalmic education. A toolbox of similar surgical competency assessment tools is being developed.

  13. Meeting Summany of the 11t France-China Ophthalmological Forum%首届中法眼科学术论坛会议概况

    Institute of Scientific and Technical Information of China (English)

    梁庆丰; Antoine Labbé; 李建军

    2013-01-01

    The 1st France-China Ophthalmological Forum was held on April 15-17th 2013 in Beijing,China.It was greatly honored to invite Professor Christophe Baudouin and his team to attend this forum of academic and scientific exchanges.During this three days forum,some interesting research and clinical projects had been discussed.Important topics in the field of ophthalmology were presented including the negative role of benzalkonium chloride in long-term glaucoma treatment,the mechanism of trans-laminar cribrosa pressure difference in glaucomatous optic neuropathy,Beijing Eye Study and animal models of dry eye.%首届中法眼科学术论坛(FCF 2013)于2013年4月15-17日在北京召开,参会代表就眼表疾病及青光眼研究的进展及热点问题进行了研讨,其中长期使用抗青光眼药物的防腐剂毒性作用、跨筛板压力差在青光眼视神经损害中作用机制研究、“北京眼病研究”及干眼模型探讨成为热点问题较为引人注目.

  14. Experience and discussion of clinical probation teaching in ophthalmology%眼科临床见习教学的体会

    Institute of Scientific and Technical Information of China (English)

    钟一声; 杨子建

    2012-01-01

    The elaborate and complex anatomy of eye, characterized by strong professional, the eye examination must be of special equipment, coupled with limited hours of theoretical curriculum, all have made it difficult to ophthalmology education. Based on the actual situation of our college, the clinical probation teaching procedure of ophthalmology in eight-year clinical medicine students has been improved, focusing on intergration theory and practice teaching, and achieved some successful teaching experiences.%眼睛的局部解剖精细复杂,专业特点强,眼科检查必须采用特殊的器械设备,加上眼科理论教学课时数少,都给眼科教学带来了困难.针对这些情况,我们教研室对临床医学专业八年制学生的眼科学临床见习教学环节进行了改进,注重理论与实践教学的衔接,取得了一些成功的教学经验.

  15. 虚拟现实技术在眼科教学中的应用%The application of virtual reality technique in ophthalmology teaching

    Institute of Scientific and Technical Information of China (English)

    李鸿; 张科

    2015-01-01

    With the development of medical theory and technology, the traditional teaching patterns have fallen behind the requirements for the training of medical students. Recently, virtual reality techniques have been proved to be effective in the practice of medical education. Through sum-marizing the experience of building simulation systems of eye anatomy, clinical features of eye and simulation practice, the author has elaborated the role of virtual reality technology in ophthalmology teaching theory and practice, which is of profound significance to improve the overall level of ophthal-mology teaching.%随着医学理论与技术的发展,传统的教学形式已不能满足当前医学教育的需要。近年来把虚拟现实技术引入医学教学,是比较新颖并切实有效的方法。在此,通过总结建造人眼解剖模拟系统、各种眼病临床特征的模拟系统以及仿真实践训练模拟系统的经验,阐述了虚拟现实技术在眼科理论和实践教学中的作用,这对提高眼科学教学整体水平有着积极意义。

  16. Objective visual field determination in forensic ophthalmology with an optimized 4-channel multifocal VEP perimetry system: a case report of a patient with retinitis pigmentosa.

    Science.gov (United States)

    Kaltwasser, C; Horn, F K; Kremers, J; Juenemann, A; Bergua, A

    2011-10-01

    We present the case of a 59-year-old male patient with progressive vision impairment and consecutive visual field narrowing ("tunnel view") for 7 years and a known retinitis pigmentosa for 5 years. The remaining Goldmann perimetric visual field at time reported was less than 5°. A request for blindness-related social benefits was rejected because an ophthalmologic expert assessment suggested malingering. This prompted us to assess an objective determination of the visual field using multifocal VEPs. Objective visual field recordings were performed with a four-channel multifocal VEP-perimeter using 58 stimulus fields (pattern reversal dartboard stimulus configuration). The correlated signal data were processed using an off-line method. At each field, the recording from the channel with the maximal signal-to-noise ratio (SNR) was retained, thus resulting in an SNR optimized virtual recording. Analysis of VEP signals was performed for each single field and concentric rings and compared to an average response measured in five healthy subjects. Substantial VEP responses could be identified in three fields within the innermost ring (eccentricity, 1.7°) for both eyes, although SNR was generally low. More eccentric stimuli did not elicit reliable VEP responses. The mfVEP recording was correlated with perimetric visual field data. The current SNR optimization by using the channel with the largest SNR provides a good method to extract useful data from recordings and may be appropriate for the use in forensic ophthalmology.

  17. The influence of Derrick T. Vail Sr, MD, and Edward M. Jackson, MD, on the creation of the American Board of Ophthalmology and the Specialist Board System in the United States.

    Science.gov (United States)

    O'Day, Denis M; Ladden, Mary R

    2012-02-01

    The claim that Derrick T. Vail Sr, MD, was the innovator behind the formation of the American Board of Ophthalmology rests on an interpretation of a single paragraph in a speech he delivered in 1908. Using the technique of historical literary criticism, we identified fundamental flaws in this interpretation based on a misunderstanding of the context of the speech and his intent. Historical review of the period, including the writings and actions of others in leadership roles, supports our contention. Vail was an influential figure at the time but was only briefly involved in the activities that led to the formation of the American Board of Ophthalmology. On the other hand, Edward M. Jackson, MD, provided inspirational and persistent leadership during the 12 years needed to bring the board into existence. He should be considered the founder of the American Board of Ophthalmology.

  18. The first korean doctor of medicine in ophthalmology: early career of Kong pyung woo (1907-1995) as an unusual example of medical profession in colonial Korea.

    Science.gov (United States)

    Kim, Tae-Ho

    2013-12-01

    This article traces early career of Kong Pyung Woo, a public figure famous for being the first doctor of medicine in ophthalmology with Korean ethnicity in 1936, for founding and running the oldest and still the most successful private eye clinic in Korea since 1937, and also for his engagement in development of Korean mechanical typewriter since 1949. His case is an illustrative example of how a Korean under the Japanese colonial rule (1910-1945) could build up a career to become a medical doctor, taking full advantage of the chances available. Kong, born in 1907 in a rural province in northwestern Korea, acquired a doctor's license in 1926 by passing the qualifying examination of the Government General in Korea. The qualification test was in itself an outcome of colonial education system, in which the supply of medical doctors by only a few tertiary schools could not meet the demands. After working for a state hospital for one year, Kong volunteered to be a visiting student at Keijo Medical College, to fulfill his dream of "becoming a prominent bacteriologist like Noguchi Hideyo." He was soon officially appointed as a tutor at Department of Ophthalmology, as he had been endorsed by professor Satake Shyuichi for his diligence and earnestness. Satake also encouraged Kong to pursue a doctoral degree and recommended him to Tokumitsu Yoshitomi, a professor in the Department of Pathology at Keijo Imperial University, so that Kong could experience cutting-edge research at the imperial university. Kong reported on his experiments on the pathology of chorioretinitis centralis by 1935. He submitted the reports to Nagoya Imperial University, Japan, as a doctoral thesis, and eventually obtained the degree in 1936, which was the first Korean doctor of medicine in ophthalmology. The doctorate made Kong a public figure and he opened his own private clinic in 1937. The Kong Eye Clinic was the first private eye clinic owned and run by Korean, and soon became popular in Seoul

  19. The Development Trend of Domestic Material for Department of Ophthalmology%我国眼科生物医用材料现状及发展趋势

    Institute of Scientific and Technical Information of China (English)

    张志雄; 奚廷斐

    2013-01-01

    Myopia, cataract, glaucoma etc are common eye diseases. The number of myopia sufferer exceeded one bil ion al over the world. Cataract is one of the dangerous eye diseases and causes high occoecatio rate. Seventeen mil ions of cataract sufferers lead to occoecatio all over the world. Biomedical materials used in ophthalmological treatment include contact lenses, artiifcial lens, artiifcial cornea, artiifcial tear duct, artiifcial eyes, viscoelastic agent, artiifcial orbital bone, long-term drugs release membrane and so on. During the last three decades, great development had been made in ophthalmological medical devices market. Global market in 2010 was twenty bil ion dol ars,and wil reach twenty-eight bil ion dol ars in 2017. Opportunities and chal enges of Chinese ophthalmological biomedical materials industry were analyzed in this article.%近视,白内障、青光眼等是常见眼科疾病。其中近视疾病最常见,全球患者超过10亿。白内障疾病危险性最高,是主要致盲的眼病之一,全球有1700万人因白内障致盲。眼科疾病治疗用生物医用材料包括角膜接触镜、人工晶状体、人工角膜、人工泪管、人工眼球、粘弹剂、人工眶骨、眼用长效药膜等。最近三十年中,眼科医疗器械市场飞速发展。据统计,2010年为200亿美元,预计2017年将达280亿美元。  本文主要对国内眼科生物医用材料产业发展面临的机遇与挑战进行分析。

  20. To expand the grand prospect of Chinese Journal of Ophthalmology following the fine tradition%继往开来再展宏图

    Institute of Scientific and Technical Information of China (English)

    赵家良; 赵堪兴

    2010-01-01

    在庆祝中华眼科杂志创刊60周年的时候,回顾过去,展望未来.60年来,经过一代又一代办刊人和广大眼科医师的努力,中华眼科杂志已经成为国内最具权威性的眼科专业杂志,形成了"敬业、惟真、奋进"的优良传统.现在,中华眼科杂志已经具备进一步发展为国内外知名的具有高度学术威信的眼科专业杂志的基础.要实现这一宏图,必须做艰苦的努力,应对前进道路上的各种挑战.要充分发挥编委会的集体作用,要继续提高编委会和编辑部全体人员的业务水平,要努力"创造"出优秀的高质量的学术论文,要遵守编辑的道德规范,要不断地听取全国眼科同道的意见、建议和批评,要加强国际合作,以促进中华眼科杂志的进步.%When we celebrate the diamond jubilee of Chinese Journal of Ophthalmology (CJO), we also reviewed its past and prospected its future. Under the effort by the editorial members and the great majority of ophthalmollogists for sixty years, CJO has become the most authoritative and academic journal in ophthalmology in China, and has formed the fine tradition of "to respect the profession, to believe the truth and to advance bravely". At present, CJO has a basis to further become the most authoritative academic journal in ophthalmology not only in the domestic but also in the world. For realizing the grand prospect, we should do more arduous effort for facing the all kind of the challenges in our ways forward; we should let the editorial committee to play the full role in our work; we should continue to raise the professional level of all editorial personnel; we should make great efforts to find and edit more and more articles with the high quality; we should observe the morals and ethics for editorial personnel; we should hear and accept the opinions, suggestions and criticisms; we should strength the international cooperation and communication.

  1. Association for Research in Vision and Ophthalmology (ARVO)--2010 Annual Meeting. For Sight: The Future of Eye and Vision Research--part 2.

    Science.gov (United States)

    Hookes, Livia

    2010-07-01

    The 2010 Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO), held in Fort Lauderdale, FL, USA, included topics covering new therapeutic developments in the field of eye and vision research. This conference report highlights selected presentations on the development of OT-440 (Othera Pharmaceuticals Inc) for the potential treatment of glaucoma, an extended-release implant of brimonidine (pSivida Corp) for ocular hypertension, AR-12286 (Aerie Pharmaceuticals Inc) for ocular hypertension or glaucoma, AC-8 (Calmune Corp/RiboVax Biotechnologies SA) for ocular diseases following HSV infection, and fidarestat (Sanwa Kagaku Kenkyusho Co Ltd) and the recombinant proteins NOV and NOVCter (INSERM/University Rene Descartes) for corneal neovascularization.

  2. 眼科学术信息资源的获取与检索途径%Acquisition and retrieval of ophthalmology academic information

    Institute of Scientific and Technical Information of China (English)

    李雷; 李鹏

    2014-01-01

    This article discusses how to search and access ophthalmology information based on specialized websites and resources by introducing the database, search engines, electronic journals, electronic books and so on. Hope to help ophthalmic practitioners to carry out scientific research and clinical practice.%本文在结合专科网站与专科资源导航的基础上,从数据库、搜索引擎、电子期刊、电子图书等方面探讨了眼科学信息资源网络获取的技术与方法,希望能够对眼科学专家和眼科从业人员开展科学研究和临床实践有所启示和帮助。

  3. 磁共振扩散张量成像在眼科的应用%Application of diffusion tensor imaging in ophthalmology

    Institute of Scientific and Technical Information of China (English)

    梁申芝; 朱豫

    2013-01-01

    Diffusion tensor imaging (DTI) is a recently developed functional MRI technique based on the random thermal motion of water molecules within tissues along different axes,which allows the quantificationally assessment of the shape,direction,arrangement,tightness,myelinization of the white matter fiber tracts in neural tissues in vivo.DTI is being widely used in the various domains of ophthalmology.In this article,the principles of DTI methodologies are explained,and several applications in ophthalmology are introduced,including optic neuropathy (ischemia,traumatic optic neuropathy,optic neuritis),glaucoma,as well as visual development and amblyopia.%磁共振扩散张量成像是一种基于分子水平上定量的功能磁共振成像技术,它能够在活体神经组织显示白质纤维束的走行、方向、排列、紧密度、髓鞘化等信息.目前磁共振扩散张量成像在眼科主要应用于视神经病变(缺血、外伤、视神经炎等)、青光眼视路病变、弱视及视觉发育等方面的研究.本文就磁共振扩散张量成像的原理及其在眼科应用及研究现状作一综述.

  4. Stem Cell Ophthalmology Treatment Study (SCOTS) for retinal and optic nerve diseases:a case report of improvement in relapsing auto-immune optic neuropathy

    Institute of Scientific and Technical Information of China (English)

    Jeffrey N Weiss; Steven Levy; Susan C Benes

    2015-01-01

    We present the results from a patient with relapsing optic neuropathy treated within the Stem Cell Ophthalmology Treatment Study (SCOTS). SCOTS is an Institutional Review Board ap-proved clinical trial and has become the largest ophthalmology stem cell study registered at the National Institutes of Health to date (www.clinicaltrials.gov Identiifer NCT 01920867). SCOTS utilizes autologous bone marrow-derived stem cells (BMSCs) for treatment of retinal and optic nerve diseases. Pre-treatment and post-treatment comprehensive eye exams of a 54 year old female patient were performed both at the Florida Study Center, USA and at The Eye Center of Columbus, USA. As a consequence of a relapsing optic neuritis, the patient’s previously normal visual acuity decreased to between 20/350 and 20/400 in the right eye and to 20/70 in the left eye. Signiifcant visual ifeld loss developed bilaterally. The patient underwent a right eye vitrectomy with injection of BMSCs into the optic nerve of the right eyeand retrobulbar, subtenon and in-travitreal injection of BMSCs in the left eye. At 15 months after SCOTS treatment, the patient’s visual acuity had improved to 20/150 in the right eye and 20/20 in the left eye. Bilateral visual fields improved markedly. Both macular thickness and fast retinal nerve fiber layer thickness were maximally improved at 3 and 6 months after SCOTS treatment. The patient also reduced her mycophenylate dose from 1,500 mg per day to 500 mg per day and required no steroid pulse therapy during the 15-month follow up.

  5. The clinical application of performance based measures of visual function in ophthalmology%生活视功能评估在眼科中的应用

    Institute of Scientific and Technical Information of China (English)

    倪薇; 王薇

    2012-01-01

    With the transformation of the modern biomedical model,the impact of diseases on patients living ability cannot be fully demonstrated solely by clinical visual tests and self-assessment questionnaires.As a new method of visual function evaluation,performance-based measures (PBM) of visual function have been introduced into the ophthalmology field.As an important supplement to traditional vision tests and vision related quality of life (QoL) questionnaires,performance-based measures of visual function may reflect the patients'actual visual impact of daily life.In this article,this newly developed method was reviewed in the field of ophthalmology.%随着现代生物医学模式的转变,单纯依靠临床视力检查和以自评问卷的方式来评估视觉生活质量已不能全面反映眼病对患者生活能力的影响.生活视功能评估方法作为一种新型视功能评价手段已引入眼科领域.作为传统视力检查和视觉生活质量自评量表的重要补充,它可更真实地反映眼病对患者实际视觉相关生活质量的影响程度.本文就生活视功能评估方法在眼科领域中的应用进行综述.

  6. Analysis of factors associated with patient satisfaction in ophthalmology: the influence of demographic data, visit characteristics and perceptions of received care.

    Science.gov (United States)

    Schoenfelder, Tonio; Klewer, Joerg; Kugler, Joachim

    2011-11-01

    To identify factors associated with satisfaction among patients receiving ophthalmic services and to indicate the intensity of this relationship. The data used was obtained through a self-administered, post-visit questionnaire from randomly selected 507 patients treated in seven eye clinics in Germany. The instrument assessed satisfaction with several aspects of care and patient baseline and visit characteristics. Bivariate and multivariate techniques were used to reveal relations between indicators and overall satisfaction. Factor analysis yielded two factors, 'medical aspects of care' and 'performance of service', explaining 55% of total variance. Cronbach's α coefficient for both scales indicates acceptable internal consistency. Bivariate analysis showed strong relations between overall satisfaction and perceived care with weaker findings pertaining to visit characteristics. Not any of the demographic variables was associated with overall satisfaction. Perceived length of stay, intention to return to the clinic, and occurrence of complications were influential attributes on satisfaction ratings. The multivariate analysis identified seven factors associated with overall satisfaction including the treatment outcome (OR: 4.57), kindness of the nurses (OR: 5.27) and medical practitioners (OR: 2.23), room amenities (OR: 2.72), organization of procedures and operations (OR: 2.71), information about anaesthesia (OR: 1.95), and cleanliness (OR: 1.93). Factors associated with patient satisfaction in ophthalmology concern medical aspects like the organization of procedures and operations but also aspects that are not directly related to technical care, such as kindness of the nurses and cleanliness. Results show that patients' subjective experiences of received care and services relate more strongly and consistently to overall satisfaction than patient demographic data or visit characteristics. Revealed factors predicting patient satisfaction are alterable by health care

  7. Progress in the basic ophthalmological research of tree shrew%树鼩在眼科学的基础研究进展

    Institute of Scientific and Technical Information of China (English)

    周广龙; 朱勤; 李振宇; 陈玲霞; 尹博文; 胡敏; 孙晓梅

    2015-01-01

    Tree shrews have an excellent visual system, their cones accounted for 96%of the photorecepter cells, so that their color vision and stereo vision are well developed.With their rich resources and low cost, tree shrews have been considered as an ideal animal model in eye research in comparative medicine and genomics research.The ophthalmological research on tree shrew mainly focused on the establishment of myopia model, as well as the changes in myopic sclera and choroids, and the basic studies of their retina, optic and visual cortex.This paper reviewed the basic ophthalmological re-search of tree shrew.%树鼩具有发达的视觉系统,视锥细胞数量占感光细胞的96%,具有较好的色觉及立体视觉。我国的树鼩资源丰富,成本较低,比较医学和基因组学研究证实树鼩是理想的眼科实验动物模型。利用树鼩开展眼科研究主要集中在近视模型的建立、近视对巩膜和脉络膜造成的变化,以及树鼩视网膜、视神经、角膜及视皮质的基础研究。本文对树鼩在眼科学方面的基础研究结果进行综述。

  8. Dependability of results in conference abstracts of randomized controlled trials in ophthalmology and author financial conflicts of interest as a factor associated with full publication.

    Science.gov (United States)

    Saldanha, Ian J; Scherer, Roberta W; Rodriguez-Barraquer, Isabel; Jampel, Henry D; Dickersin, Kay

    2016-04-26

    Discrepancies between information in conference abstracts and full publications describing the same randomized controlled trial have been reported. The association between author conflicts of interest and the publication of randomized controlled trials is unclear. The objective of this study was to use randomized controlled trials in ophthalmology to evaluate (1) the agreement in the reported main outcome results by comparing abstracts and corresponding publications and (2) the association between the author conflicts of interest and publication of the results presented in the abstracts. We considered abstracts describing results of randomized controlled trials presented at the 2001-2004 Association for Research in Vision and Ophthalmology conferences as eligible for our study. Through electronic searching and by emailing abstract authors, we identified the earliest publication (journal article) containing results of each abstract's main outcome through November 2013. We categorized the discordance between the main outcome results in the abstract and its paired publication as qualitative (a difference in the direction of the estimated effect) or as quantitative. We used the Association for Research in Vision and Ophthalmology categories for conflicts of interest: financial interest, employee of business with interest, consultant to business with interest, inventor/developer with patent, and receiving ≥ 1 gift from industry in the past year. We calculated the relative risks (RRs) of publication associated with the categories of conflicts of interest for abstracts with results that were statistically significant, not statistically significant, or not reported. We included 513 abstracts, 230 (44.8 %) of which reached publication. Among the 86 pairs with the same main outcome domain at the same time point, 47 pairs (54.7 %) had discordant results: qualitative discordance in 7 pairs and quantitative discordance in 40 pairs. Quantitative discordance was indicated

  9. The visual difficulties of selected artists and limitations of ophthalmological care during the 19th and early 20th centuries (an AOS thesis).

    Science.gov (United States)

    Ravin, James G

    2008-01-01

    To investigate the effects of eye diseases on several important artists who have been given little attention from a medical-historical viewpoint. The examples chosen demonstrate problems artists have had to face from different types of eye disease, including cataract, glaucoma, and retinal diseases. The ophthalmological care provided is described in terms of scientific knowledge at the time. Investigation of primary and secondary source material. Discussion with art historians and ophthalmic historians. Examination of work by the artists. Artists can be markedly affected by ocular diseases that change their ability to see the world. The individuals described here worked during the 19th century and first half of the 20th century. Homer Martin suffered from cataracts, and his works reveal changes in details and color as he aged. Henri Harpignies, who had an extremely long career, undoubtedly had cataracts and may also have had macular degeneration. Angle-closure glaucoma blinded Jules Chéret. Auguste Ravier suffered from neovascular glaucoma in one eye and was able to work with his remaining eye, which developed a cataract. Louis Valtat suffered from what was in all likelihood open-angle glaucoma, but specific changes due to this disease are not apparent in his work. Roger Bissière developed glaucoma and did well following filtration surgery. George Du Maurier lost one eye from what was probably a retinal detachment and later suffered from a central retinal problem in the other eye. Diseases of the eye may profoundly influence artists by altering their perception of the world. The specific effects may vary, depending on the disease, its severity, and the psychology of the artist. Cataracts typically affect an artist's ability to depict color and detail. The effect of glaucoma generally depends on whether central vision is preserved. Disease that affects the center of the retina has a substantial effect on an artist's ability to depict fine details. Ophthalmological

  10. Application of optical density studies with optical coherence tomography in ophthalmology%OCT的光密度研究在眼科的应用

    Institute of Scientific and Technical Information of China (English)

    陈镔瑶

    2014-01-01

    光密度测量是一种通过结合计算机技术,将待测组织的图像信号转换成数字化格式,分析图像像素及计算后获得待测组织透射/反射光强度,从而达到客观分析组织特性的一种分析技术.光密度可根据测量仪器产生图像的维度而提供二维或三维的信息,立体、全面地体现组织内部微结构的变化,近年来在眼科影像中逐渐引起关注,已有研究表明其在眼科疾病诊断及随访中的应用价值.现结合国内外研究从光密度的定义、光密度在各领域的应用、光密度测量的优缺点、眼科领域中的光密度分析方法、光学相干断层扫描的光密度研究在眼科疾病中的应用5个方面进行综述.%Optical density (OD) analysis is a kind of technology that analyzes transmitted/reflective light intensity of target tissue to learn certain characters of tissue objectively by calculating pixel values of tissue image with the help of computer technology.OD can provide 2-dimensional or 3-dimensional information and embody tiny changes of tissue systematically.It has aroused attention gradually in ophthalmology imaging in recent years.Various studies had shown diagnositc and prognostic value of OD in ocular diseases.This paper reviewed the definition of OD,application of OD in various fields,advantages and disadvantages of OD,analysis method of OD and application of OD in ophthalmology.

  11. Efficacy of TNF-α antagonist and other immunomodulators in the treatment of patients with ophthalmologic manifestations of Behcet's disease and HLA B51 positive vasculitis

    Directory of Open Access Journals (Sweden)

    Zlatanović Gordana

    2012-01-01

    Full Text Available Bacground/Aim. Behcet's disease is genetically conditioned, immune-mediated multisystem occlusive vasculitis of small blood vessels, espesially venules, of unknown etiology. The aim of this study was to analyze the clinical features, disease activity and therapy of the patients with ophthalmologic manifestation of Behcet's disease. Methods. In this study symptoms and signs of the disease were analyzed both prospectively and retrospectively during the active manifestation of the disease. The diagnosis was reached according to the International Criteria for Behcet's Disease (2006. The treatment effects were evaluated based on the presence of the best corrected visual acuity and the inflammation of the vitreous humour before and after the application of our therapeutic method. The applied therapeutic modality consisted of the primary application of corticosteroid therapy in the active stage of the disease complemented with the choice of drugs from the immunosuppressive group. In this study there drugs were cyclosporine or methotrexate. A treatment refractory patients with poor vision prognosis were treated with a third drug, the biological preparation infliximab, a tumor necrosis factor-alpha (TNF-α antagonist. Results. The mean age of 11 patients with ophthalmologic manifestation of Behcet's disease was 50.6 years. HLA B-5(51 was positive in 81% of the patients while 36% of the patients had positive pathergy test. Changes in affected eyes included vitritis (100%, posterior uveitis (45%, panuveitis (54%, retinal vasculitis (54%, cystoid macular edema (54%, and cystoid degeneration (18%. Increased intraocular pressure was observed in 27% of the patients. There was no statistically significant variation in disease activity parameters in any of the patients (p > 0.05. A statistically significant improvement in visual acuity (p < 0.05 and a high statistically significant decrease of inflammation of the worst affected eyes (p = 0.001 were detected

  12. Clinical profile, evaluation, management and visual outcome of idiopathic intracranial hypertension in a neuro-ophthalmology clinic of a tertiary referral ophthalmic center in India

    Directory of Open Access Journals (Sweden)

    Ambika S

    2010-01-01

    Full Text Available Aim: To discuss the clinical features and management of patients who presented with optic disc edema and had features of presumed idiopathic intracranial hypertension (IIH. Materials and Methods: Case series of all patients diagnosed to have IIH from January 2000 to December 2003 in the neuro-ophthalmology clinic of a tertiary referral ophthalmic institution, were retrospectively analyzed. Analysis was done for 50/106 patients who fulfilled modified Dandy′s criteria and had optic disc edema and a minimal follow-up period of two years. Results: Most (40/50, 80% of the patients were females and the mean age of presentation for all the 50 patients was 32.89 years. Chief complaints were headache in 38 (76% patients, 24 (48% patients had transient visual obscuration, 24 (48% patients had reduced vision, 15 (30% patients had nausea, vomiting, 4 (8% patients had diplopia. Bilateral disc edema was seen in 46 (92% patients and unilateral disc edema in 4 (8% patients. 60 eyes had enlarged blind spot as the common visual field defect. Neuroimaging revealed prominent perioptic CSF spaces in 14 patients and empty sella in three patients. CSF opening pressure was 250-350 mm H2O (water in 39 patients and was > 350 mm H2O in 11 patients. Medical treatment was started for all patients; whereas 35 [70%] patients responded, 15 [30%] patients had to undergo LP shunt.

  13. Growth factor of Connective tissue Disease in Department of Ophthalmology%结缔组织生长因子在眼科疾病中的研究

    Institute of Scientific and Technical Information of China (English)

    朱海英

    2015-01-01

    Through the study on the expression of connective tissue growth factor,analysis ofthe relationship between the structure and the eye of connective tissue growth factor,can provide a more effective method for the treatment of diseases in Department of ophthalmology.As a result of connective tissue growth factor in vivoshowed widespread expression,and with many ocular diseases are closely related.Therefore,blocking or inhibiting connective tissue growth factor plays an important role in the treatment of eye diseases.%本文通过研究结缔组织生长因子表达,分析眼部结构与结缔组织生长因子的关系,为眼科疾病的治疗提供更有效的治疗方法。由于结缔组织生长因子在体内广泛表达,且与许多眼部疾病均密切相关。因此,阻断或抑制结缔组织生长因子对于眼部疾病治疗具有重要作用。

  14. Development of a New Valid, Reliable, and Internationally Applicable Assessment Tool of Residents’ Competence in Ophthalmic Surgery (An American Ophthalmological Society Thesis)

    Science.gov (United States)

    Golnik, C.; Beaver, Hilary; Gauba, Vinod; Lee, Andrew G.; Mayorga, Eduardo; Palis, Gabriela; Saleh, George M.

    2013-01-01

    Purpose: To test the validity and reliability of a new tool for assessing residents’ competence in ophthalmic surgery. Changing paradigms of ophthalmic education in the United States have influenced worldwide ophthalmic education and necessitated new methods of assessing resident competence. Accordingly, a new tool for assessing residents’ competence in ophthalmic surgery (phacoemulsification) that could be applicable internationally was developed. We hypothesize that this instrument is valid and reliable. Methods: A panel of six international content experts adapted a previously published tool for assessing phacoemulsification. The tool (called the International Council of Ophthalmology’s Ophthalmology Surgical Competency Assessment Rubric, or ICO-OSCAR:phaco) was reviewed by 12 international content experts for their constructive comments, which were incorporated to ensure content validity. Ten expert cataract surgery teachers then graded six recorded phacoemulsification surgeries with the ICO-OSCAR:phaco to investigate inter-rater reliability. Results: The coefficient alpha statistic (a measure of reliability/internal consistency) for the ICO-OSCAR:phaco as a whole was 0.92, and 17 of its 20 dimensions had alpha coefficients greater than 0.70. Conclusions: The ICO-OSCAR:phaco is a valid and reliable assessment tool that could be applied internationally to satisfy the global need of new instruments to comply with emerging trends in ophthalmic education. A toolbox of similar surgical competency assessment tools is being developed. PMID:24072944

  15. Generation and evaluation of a human corneal model cell system for ophthalmologic issues using the HPV16 E6/E7 oncogenes as uniform immortalization platform.

    Science.gov (United States)

    Schulz, Simon; Steinberg, Thorsten; Beck, David; Tomakidi, Pascal; Accardi, Rosita; Tommasino, Massimo; Reinhard, Thomas; Eberwein, Philipp

    2013-01-01

    The present study aimed at employing the human papillomavirus type 16 (HPV16) E6/E7 gene platform, to create a uniform authentic in vitro model cell system of the human cornea for ophthalmologic issues and here especially for prospective biomaterial evaluations for therapeutic regenerative approaches. Therefore, HPV16 E6/E7 genes were employed as uniform platform to immortalize primary human corneal keratinocytes (IHCK), fibroblasts (IHCF), and endothelial (IHCE) cells. qPCR revealed that E6/E7 mRNA transcription persisted at rising passages and FISH detection of the chromosome portfolio 1, 8, 10 and 18 showed fairly the disomic cytogenetic status. Hot spot passages proved oscillation of aneuploidies in the entire passage spectrum under study, while hot spot aneuploidies annotated prevalence for distinct chromosomes. Though IIF revealed general endurance, tissue-innate corneal biomarkers were modulated, i.e. expressed in a temporal-confluence, temporal-spatial or passage-dependent manner. In summary, by the fairly normal chromosomal status, and expression of tissue-innate biomarkers, we created for the first time a uniform authentic in vitro model cell system of the human cornea, by application of the HPV16 E6/E7 immortalization platform only. This system renders a precious tool for prospective iterative in vitro studies on issues such as corneal tissue homeostasis, pharmaceutical generics, and/or evaluation of new biomaterials for clinical corneal applications. Copyright © 2013 International Society of Differentiation. Published by Elsevier B.V. All rights reserved.

  16. Usos de la membrana amniótica humana en oftalmología Some uses of human amniotic membrane in Ophthalmology

    Directory of Open Access Journals (Sweden)

    Jaime Alemañy González

    2006-06-01

    Full Text Available Se realizó una revisión bibliográfica sobre el uso de la membrana amniótica en oftalmología con los propósitos de conocer sus mecanismos de acción y aplicaciones, así como los resultados publicados sobre el transplante de membrana amniótica humana en la superficie ocular. Se estudiaron textos y artículos publicados sobre este tipo de tratamiento en las enfermedades y traumas de córnea, conjuntiva, esclera y párpados. Se concluye que es una alternativa terapéutica valida que puede ser de gran utilidad en nuestro medioA literature review was made on the use of amniotic membrane in ophthalmology, with the objective of finding out its mechanisms of action and applications as well as the results of human amniotic membrane transplantation for ocular surface reconstruction. A number of texts and articles published on this type of treatment for cornea, conjunctiva, sclera and eyelids diseases and traumas were studied. It was concluded that this is a valid therapeutical alternative that may be very beneficial in our context

  17. Ética organizacional: um estudo em clínicas oftalmológicas Organizational ethics: a study in ophthalmologic clinics

    Directory of Open Access Journals (Sweden)

    Maria Aparecida Sanches

    2005-12-01

    Full Text Available OBJETIVO: Pesquisar no campo da ética organizacional para averiguar até que ponto as clínicas oftalmológicas, imersas no ambiente competitivo, na condição de organizações em busca de sobrevivência, subordinam a ética à competitividade na práxis gerencial, isto é, na esfera da administração. MÉTODOS: Toma Kohlberg como referencial teórico, abordando o tema da subordinação ética à competitividade. Aplicou instrumento para avaliar comportamentos morais das organizações, elaborado por Licht. Faz uso de método quantitativo, adotando instrumentos analíticos, tais como Q de Yule e testes não paramétricos, no tratamento dos dados de 41 clínicas oftalmológicas. RESULTADOS: Os resultados da pesquisa parecem indicar que administradores de clínicas oftalmológicas de maior desempenho, subjugam os princípios éticos à competitividade, com vistas a assegurar a sobrevivência da empresa e, quando aferidos pelo instrumento para avaliar seu comportamento moral, proposto por Kohlberg, têm presença significativamente menor no estágio pós-convencional do que administradores de clínicas oftalmológicas de menor desempenho. Pode-se afirmar, de acordo com os testes não paramétricos, que, ao nível de significância de 0,05, os níveis de desenvolvimento moral dos dois grupos diferem significativamente. CONCLUSÕES: Os resultados obtidos estão conforme a literatura, especialmente no tocante ao "paradoxo da subordinação ética e competitividade". Vão também ao encontro de que a garantia da sobrevivência da empresa tende a diminuir a percepção dos grupos no poder no que se refere aos problemas ocorridos na comunidade e que ocorre redução dos valores éticos subordinados à competição, redução esta que provoca sentimentos crescentes de disputas econômicas na esfera social.PURPOSE: Research on the field of organizational ethics to investigate to which extent ophthalmologic clinics, inserted in the competitive atmosphere

  18. Top ten progression of neuro-ophthalmology research in China in the latest five years%我国神经眼科近五年十大研究进展

    Institute of Scientific and Technical Information of China (English)

    中华医学会眼科学分会神经眼科学组

    2014-01-01

    神经眼科专业在我国起步较晚,近年来发展迅速.通过作者自荐、专家投票等方式,中华医学会眼科学分会神经眼科学组选出近5年(2009至2013年)我国神经眼科领域影响较大的十个研究进展,主要涵盖的内容包括视神经炎临床及基础研究、缺血性视神经病变的研究、Leber遗传性视神经病变等系列研究,基本代表了我国神经眼科医师近几年的努力成果.%Ten researches that represent the most advanced neuro-ophthalmology related studies in china were voted by specialists from Chinese Neuro-ophthalmology Society.These researches were concentrated in the following fields:clinical and basic researches of optic neuritis,studies of ischemic optic neuropathy,and clinical present of Leber's hereditary optic neuropathy.These researches represented the level of neuro-ophthalmology in China and also showed the focus of our Chinese neuro-ophthalmologists in recent years.(Chin J Ophthalmol,2014,50:915-917)

  19. Application of case - based learning teaching mode in ophthalmology clinical teaching%CBL教学模式在眼科学临床教学中的应用

    Institute of Scientific and Technical Information of China (English)

    刘莹; 王佟; 吴薇; 任甫

    2016-01-01

    目的:评价以病例为基础的教学法( case-based learning, CBL)在眼科学教学实践中的作用。  方法:以课堂授课为主结合CBL教学的形式,对锦州医科大学感觉器官教学改革班的88名学生进行教学,教学结束后以填写问卷调查的形式了解学生对于CBL教学的评价。  结果:按每个选项的百分比来进行数据的描述分析。所有学生都接受CBL在教学内容结束后进行,大部分学生认可该教学模型,认为它有助于学生对临床疾病治疗原则的理解把握,增加教学过程中的趣味性,有利于复习所学知识及锻炼临床病例分析能力,并能深刻地认识眼科疾病及特殊的辅助检查。 CBL教学模式可以激发学生对眼科学的学习兴趣,有利于理论结合实际以及临床思维的培养。  结论:CBL教学可作为传统LBL教学的辅助教学方式。%AIM: To evaluate the case-based learning ( CBL ) in ophthalmology teaching practice. METHODS: A total of 88 students were taught by the combination of lecture-based teaching with CBL form of sensory organs in Jinzhou Medical Teaching Classes. After class, the questionnaire was filled by each student to evaluate the CBL teaching mode. RESULTS:The description of the data was analyzed as a percentage of each option. All the students were taught by CBL at the end of the class, most of the students could accept the teaching mode, it was helpful for students to understand the principle of clinical treatment, increased the interest in the process of teaching. And it was conducive to review the knowledge and exercise clinical case analysis ability. And it could recognize the ophthalmic diseases and special auxiliary examination. CBL teaching mode could stimulate students' interest in learning ophthalmology, it was beneficial to the cultivation of theory combined with practice and clinical thinking. CONCLUSION: CBL teaching mode can be used as an auxiliary teaching lecture

  20. Safety Hidden Trouble and Prevention Measures in the Ophthalmology Nursing%眼科护理中的安全隐患及防范对策

    Institute of Scientific and Technical Information of China (English)

    伍群华; 张冬梅

    2016-01-01

    目的:研究探讨眼科护理中存在的不安全因素以及制定有效防范对策。方法在过往病例当中,选取2014年1月~2015年12月我院收治的80例眼科患者,随机分为对照组和观察组,各40例,根据护理措施不同,对照组用一般护理方式,观察组用综合护理干预。分析护理工作中潜在的不安全因素,并探讨有效的解决对策。结果眼科护理主要风险因素有视力模糊、睡眠障碍、体位不适、焦虑、便秘。观察组的护理满意度明显高于对照组,差异有统计学意义(<0.05),护理效果显著提高。结论应用科学的管理手段,健全各项护理安全管理制度,制定有效的安全防患措施,可使眼科护理引起的安全隐患得到根本控制,并保证患者的安全,提高患者护理满意度。%Objective To explorer the unsafe factors in the department of ophthalmology nursing and develop effective preventive measures. Methods In the past cases, select 80 cases of ophthalmic patients from the January 2014 to December 2015 in our hospital, randomly divided into the observation group and the control group,each of 40 cases. According to the different nursing measures. The control group was treated with general nursing,and the observation group was treated with comprehensive nursing intervention. To analyze the potential unsafe factors in nursing work, and to explore effective countermeasures. Results Major risk factors in eye care is a blurred vision, sleep disorders, postural discomfort, anxiety and constipation.The nursing satisfaction of observation group was significantly higher than that of the control group,the difference was statistically significant ( <0.05), and the nursing effect was significantly improved. Conclusion The application of scientific management methods, improve the nursing safety management system,formulate effective safety prevention measures, can make the department of ophthalmology nursing safety

  1. Importância da avaliação oftalmológica em recém-natos Importance of the ophthalmological evaluation in newborns

    Directory of Open Access Journals (Sweden)

    Daniel Wasilewski

    2002-01-01

    Full Text Available Objetivo: verificar a existência de afecções oculares, nas primeiras 48 horas de vida de recém-natos, e relacioná-las com a suspeita clínica dos pediatras. Métodos: realizou-se um estudo prospectivo em que todos os recém-natos no período de julho a dezembro de 2000 foram examinados no alojamento conjunto do Hospital Universitário Evangélico de Curitiba (HUEC. Seiscentos e sessenta e sete recém-natos foram avaliados, através de um protocolo, por médicos residentes e preceptores de oftalmologia, independentemente se havia ou não qualquer suspeita de alteração ocular pelo pediatra. Procedeu-se à inspeção, iluminação oblíqua, avaliação de desvio ocular e oftalmoscopia direta à distância (reflexo vermelho em todos os pacientes. Resultados: em 3,75% dos pacientes avaliados, encontrou-se alguma alteração ocular. A principal afecção ocular foi a opacidade corneana, detectada pelo exame de reflexo vermelho à distância. Cinqüenta e seis por cento dos recém-natos portadores de patologia ocular passaram despercebidos pelos pediatras, neonatologistas e pais. Conclusão: este estudo demonstrou que a maioria das desordens oculares presentes ao nascimento não é diagnosticada pelos pediatras (56%, evidenciando, desta forma, a importância do exame oftalmológico como rotina no atendimento ao recém-nato nas primeiras 48 horas de vida.Objective: To verify the existence of ocular diseases in the first 48 hours of life of newborns and relate it to the clinical suspicious of pediatricians. Methods: A prospective study was performed. All infants that were born between July and December of 2000 were evaluated in the nursery of Hospital Universitário Evangélico de Curitiba (HUEC. Six hundred sixty-seven newborns were evaluated through a protocol by residents and tutors of ophthalmology, regardless of pediatricians’ suspicious of ocular disorder. The examination consisted of inspection, oblique illumination, evaluation of ocular

  2. 视网膜血氧测定仪在眼科的应用进展%Application of retinal oximeter in ophthalmology

    Institute of Scientific and Technical Information of China (English)

    李静; 马建民; 王宁利

    2015-01-01

    视网膜血氧测定仪是近年来开始用于眼科疾病诊疗和研究的仪器,可以直接检测视网膜的血氧饱和度,有望为眼科医师更深入地了解眼科疾病提供了新的途径和角度,并阐明视网膜缺血对其功能的影响.目前文献已经报道,视网膜血氧测定仪在包括糖尿病性视网膜病变、视网膜中央动静脉阻塞、视网膜色素变性及青光眼性视神经病变等在内的多种眼病的诊断和治疗中有潜在价值.本文就视网膜血氧测定仪在眼科疾病中的应用进展进行综述.%Retinal oximeter is a new machine which has been used in the diagnose, treatment and research of several ophthalmic diseases for recent years.It allows ophthalmologists to gain retinal oxygen saturation directly.Therefore, retinal oximeter might be useful for ophthalmologists to understand ophthalmic diseases more deeper and clarify the impact of ischemia on retinal function.It has been reported in the literatures that retinal oximeter has potentially useful diagnostic and therapeutic indications in various eye diseases such as diabetic retinopathy, central retinal vein and artery occlusion, retinitis pigmentosa, glaucomatous optic neuropathy, et al.In this thesis, the application of retinal oximeter in ophthalmology is reviewed.

  3. 脂肪干细胞在眼科的应用及研究进展%Development and application of adipose-derived stem cells in ophthalmology

    Institute of Scientific and Technical Information of China (English)

    李宏松; 邹俊

    2013-01-01

    Adipose-derived stem cells ( ADSCs ) are multipotent population of cells with multipotential differentiation capability, which can differentiate into mesoderm including adipocyte osteoblasts and chondroblasts in specific conditions, even the endoderm cells like hepatocyte and and ectoderm cells like neurocyte. Besides, ADSC has many advantages like easy access and light damage to selected area, which enables it to become a hotspot in tissue repair area. This paper made a classified summary on the biological characteristics of corneal epithelium and its application in research to offer beneficial hints to the research of ADSC application in ophthalmology.%脂肪干细胞( adipose-derived stem cells , ADSCs )是存在于脂肪组织的间充质干细胞,具有多向分化潜能,在特定的条件下可以分化为脂肪细胞、成骨细胞、成软骨细胞等中胚层细胞,甚至可以跨胚层分化为神经细胞等外胚层细胞及肝细胞等内胚层细胞。ADSCs还有易于获取、对取材区损伤小等众多优势,使其成为组织修复等领域的热点之一。本文对ADSCs的生物学特性及其在眼科领域的研究进行了分类总结,以期为 ADSCs在眼科的应用研究给予有益的提示。

  4. Work hard to develop neuro-ophthalmology in China%脚踏实地加速我国神经眼科学术水平发展

    Institute of Scientific and Technical Information of China (English)

    魏世辉

    2014-01-01

    神经眼科是交叉学科,其中视神经炎、缺血性视神经病变等一直是神经眼科医师关注的热点.目前我国有关视神经炎的流行病学研究、病因诊断及临床特点研究正在进行中,而我国视神经炎诊断和治疗专家共识已经公开发表并在推广中.缺血性视神经病变的发病机制、治疗手段也是当前的研究热点,并且存在争论,而针对我国的缺血性视神经病变流行病学研究目前已提上日程.后视路疾病的治疗在我国一直被忽视,其急性期和慢性期的治疗均应得到重视.%Neuro-ophthalmology is a crossing discipline.Optic neuritis and ischemic optic neuropathy are the hot points of this field.Currently,studies of optic neuritis epidemiology,etiology and clinical features have already been done in china.And the expert consensus of optic neuritis therapy was published.The pathogenesis and treatment of ischemic optic neuropathy is another hot point.We have embarked on the epidemiological study of ischemic optic neuropathy in china.We also appeal the ophthalmologists to pay more attention on the therapy of posterior visual pathway.(Chin J Ophthalmol,2014,

  5. CROP - The Clinico-Radiologico-Ophthalmological Paradox in Multiple Sclerosis: Are Patterns of Retinal and MRI Changes Heterogeneous and Thus Not Predictable?

    Directory of Open Access Journals (Sweden)

    Fahmy Aboulenein-Djamshidian

    Full Text Available To date, no direct scientific evidence has been found linking tissue changes in multiple sclerosis (MS patients, such as demyelination, axonal destruction or gliosis, with either steady progression and/or stepwise accumulation of focal CNS lesions. Tissue changes such as reduction of the retinal nerve fiber layer (RNFL and the total macular volume (TMV, or brain- and spinal cord atrophy indicates an irreversible stage of tissue destruction. Whether these changes are found in all MS patients, and if there is a correlation with clinical disease state, remains controversial. The objective of our study was to determine, whether there was any correlation between the RNFL or TMV of patients with MS, and: (1 the lesion load along the visual pathways, (2 the ratios and absolute concentrations of metabolites in the normal-appearing white matter (NAWM, (3 standard brain atrophy indices, (4 disease activity or (5 disease duration.28 MS patients (RRMS, n = 23; secondary progressive MS (SPMS, n = 5 with moderately-high disease activity or long disease course were included in the study. We utilised: (1 magnetic resonance imaging (MRI and (2 -spectroscopy (MRS, both operating at 3 Tesla, and (3 high-resolution spectral domain-OCT with locked reference images and eye tracking mode to undertake the study.There was no consistency in the pattern of CNS metabolites, brain atrophy indices and the RNFL/TMV between individuals, which ranged from normal to markedly-reduced levels. Furthermore, there was no strict correlation between CNS metabolites, lesions along the visual pathways, atrophy indices, RNFL, TMV, disease duration or disability.Based on the findings of this study, we recommend that the concept of 'clinico-radiologico paradox' in multiple sclerosis be extended to CROP-'clinico-radiologico-ophthalmological paradox'. Furthermore, OCT data of MS patients should be interpreted with caution.

  6. Finding self-directed learning readiness and fostering self-directed learning through weekly assessment of self-directed learning topics during undergraduate clinical training in ophthalmology

    Science.gov (United States)

    Sahoo, Soumendra

    2016-01-01

    Background: To know the individual’s current level of readiness and to manage self-directed learning (SDL) not only help learners but also the instructors. The objectives of this study were to find SDL readiness among 4th year medical student and to analyze the effect of weekly assessment of SDL topics. Methodology: This was a cross-sectional study to analyze the effect of weekly assessment of SDL topics in fostering SDL. The 51 4th year students during a clinical posting in ophthalmology participated for this study. Each recruited student was tested for SDL readiness through the SDL readiness scale (SDLRS) developed by Lucy Guglielmino (1978), which was validated in our local setting and responses were collected from students on the 1st day of the clinical posting. The students chose SDL topics which were assessed on a weekly basis in the form of scenario-based multiple choice questionnaires. Written feedback was collected from each student regarding such activity during their clinical posting, especially to know the actual utilization of SDL hours provided in teaching schedule, satisfaction on the type of questions and motivation for SDL. Results: The mean SDLRS score in male students were 214.15 ± 19.73 and in female 207.95 ± 17.983, which falls under average score as defined in Guglielmino scale. The majority of study population expressed better utilization of SDL study hours because of weekly assessment than when they had no assessment for SDL. Conclusions: Majority of the study population were found to be ready for SDL. The weekly assessment of SDL topics was found to stimulate proper utilization of SDL slots in teaching schedule thereby fostering SDL habits. PMID:27563580

  7. Finding self-directed learning readiness and fostering self-directed learning through weekly assessment of self-directed learning topics during undergraduate clinical training in ophthalmology.

    Science.gov (United States)

    Sahoo, Soumendra

    2016-01-01

    To know the individual's current level of readiness and to manage self-directed learning (SDL) not only help learners but also the instructors. The objectives of this study were to find SDL readiness among 4(th) year medical student and to analyze the effect of weekly assessment of SDL topics. This was a cross-sectional study to analyze the effect of weekly assessment of SDL topics in fostering SDL. The 51 4(th) year students during a clinical posting in ophthalmology participated for this study. Each recruited student was tested for SDL readiness through the SDL readiness scale (SDLRS) developed by Lucy Guglielmino (1978), which was validated in our local setting and responses were collected from students on the 1(st) day of the clinical posting. The students chose SDL topics which were assessed on a weekly basis in the form of scenario-based multiple choice questionnaires. Written feedback was collected from each student regarding such activity during their clinical posting, especially to know the actual utilization of SDL hours provided in teaching schedule, satisfaction on the type of questions and motivation for SDL. The mean SDLRS score in male students were 214.15 ± 19.73 and in female 207.95 ± 17.983, which falls under average score as defined in Guglielmino scale. The majority of study population expressed better utilization of SDL study hours because of weekly assessment than when they had no assessment for SDL. Majority of the study population were found to be ready for SDL. The weekly assessment of SDL topics was found to stimulate proper utilization of SDL slots in teaching schedule thereby fostering SDL habits.

  8. Nigerian Journal of Ophthalmology: Submissions

    African Journals Online (AJOL)

    Link for new author registration is available from the home page .... effects on patient care and health policy, possible mechanisms); Controversiesraised by this .... Law and procedures, Wolters Kluwer India Private Ltd, would be charging service .... works in any digital medium for any reasonable non-commercial purpose, ...

  9. Carotid cavernous fistula: Ophthalmological implications

    Directory of Open Access Journals (Sweden)

    Chaudhry Imtiaz

    2009-01-01

    Full Text Available Carotid cavernous fistula (CCF is an abnormal communication between the cavernous sinus and the carotid arterial system. A CCF can be due to a direct connection between the cavernous segment of the internal carotid artery and the cavernous sinus, or a communication between the cavernous sinus, and one or more meningeal branches of the internal carotid artery, external carotid artery or both. These fistulas may be divided into spontaneous or traumatic in relation to cause and direct or dural in relation to angiographic findings. The dural fistulas usually have low rates of arterial blood flow and may be difficult to diagnose without angiography. Patients with CCF may initially present to an ophthalmologist with decreased vision, conjunctival chemosis, external ophthalmoplegia and proptosis. Patients with CCF may have predisposing causes, which need to be elicited. Radiological features may be helpful in confirming the diagnosis and determining possible intervention. Patients with any associated visual impairment or ocular conditions, such as glaucoma, need to be identified and treated. Based on patient′s signs and symptoms, timely intervention is mandatory to prevent morbidity or mortality. The conventional treatments include carotid ligation and embolization, with minimal significant morbidity or mortality. Ophthalmologist may be the first physician to encounter a patient with clinical manifestations of CCF, and this review article should help in understanding the clinical features of CCF, current diagnostic approach, usefulness of the available imaging modalities, possible modes of treatment and expected outcome.

  10. Photobiomodulation (PBM) Applications in Ophthalmology

    Science.gov (United States)

    Dotson, Robert

    2011-03-01

    In a very real sense, we are all creatures of light. This fact is just now beginning to impact medicine, as quantum theory begins to spread outside the confines of physics and into the life sciences. No longer can living organisms simply be viewed as retorts for biochemical reactions. They also demonstrate an energy component that will prove to be the unifying force of life in all its varied forms. With the advent of this shift in the life sciences, light is becoming an increasingly important diagnostic and therapeutic tool within medicine. Ophthalmologists have long been concerned with light and its application and, consequently, have an interest in the coming scientific revolution, photomedicine. A brief history of the use of low energy light for healing, a review of known mechanisms by which photons interact with living cells, and a review of some of the established cellular effects will be presented. Finally, brief clinical studies will be presented illustrating the benefits of PBM - specifically regarding: corneal healing, glaucoma, and dry age-related macular degeneration. The purpose of this talk is to introduce the emerging field of PBM to the physics community at large.

  11. Molecular diagnosis: Implications for ophthalmology.

    Science.gov (United States)

    Rosenbaum, James T; Sibley, Cailin H; Choi, Dongseok; Harrington, Christina A; Planck, Stephen R

    2016-01-01

    The effort to subdivide diseases and to individualize therapies based on characteristics of the patient has been labeled precision medicine. Jameson and Longo define precision medicine as "treatments targeted to the needs of individual patients on the basis of genetic, biomarker, phenotypic or psychosocial characteristics that distinguish a given patient from other patients with similar clinical presentations" (Jameson and Longo, 2015). We illustrate how molecular diagnosis can be applied to orbital inflammatory disease to achieve the goals of precision medicine.

  12. Ophthalmologic aspects of chikungunya infection.

    Science.gov (United States)

    Martínez-Pulgarín, Dayron F; Chowdhury, Fazle Rabbi; Villamil-Gomez, Wilmer E; Rodriguez-Morales, Alfonso J; Blohm, Gabriela M; Paniz-Mondolfi, Alberto E

    Chikungunya fever, a viral disease epidemic in some parts of the world is newly introduced in the Americas. This is of considerable international concern, with a growing incidence owing to developing urbanization, tourism, and trade. Ocular manifestations of chikungunya fever are not frequent, but of great relevance. Common manifestations include conjunctivitis, optic neuritis, iridocyclitis, episcleritis, retinitis and uveitis. Diagnostic and monitoring investigations would include optical coherence tomography, fundus fluorescein and indocyanine green angiography, visual field analysis, and electrophysiologic tests. There have been no prospective, randomized therapeutic trials, and it is unclear if the disease is self-limiting or if treatment is actually beneficial. Prognosis varies, ranging from full resolution to permanent vision loss despite intervention. Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. 个性化护理在眼科手术患者中的应用效果分析%Application effect analysis of personalized nursing in ophthalmology operation patients

    Institute of Scientific and Technical Information of China (English)

    柴树洁; 于方; 衡朝霞; 梁义红

    2013-01-01

    Objective:To explore the effect of personalized nursing in ophthalmology operation patients. Methods:260 cases of ophthalmology operation patients were randomly divided into two groups, 130 cases in the control group were received general nursing, 130 cases in the experimental group were given personalized nursing on the basic of general nursing, and the effects of two groups were compared. Results:After receiving individualized nursing, the anxiety relieve were significantly better than that in the control group(P﹤0.05); The patient's satisfaction in the experimental group were significantly higher than that in the control group(P﹤0.05). Conclusion:Personalized nursing can reduce the anxiety level of ophthalmology perioperative patients, improve patient's satisfaction, it is wel worth clinical application.%目的:探讨个性化护理在眼科手术患者中的应用效果。方法:将我院收治的260例眼科手术患者随机分成两组,对照组130例实施常规护理,实验组130例在常规护理基础上给予全面的个性化护理,并对其应用效果进行评价。结果:接受个性化护理后,实验组的手术焦虑状态明显减轻,优于对照组;患者对护理工作满意度也明显高于对照组。结论:个性化护理能有效缓解眼科围手术期患者的焦虑状态,提高护理满意度,值得临床推广。

  14. 地市级医院眼科亚专科建设的探索%Exploration of Construction of Ophthalmology Subspeciality in the Prefec-ture-level Hospitals

    Institute of Scientific and Technical Information of China (English)

    高丰

    2016-01-01

    该文就如何进一步增强地市级医院眼科的创新能力和核心竞争力,在眼科亚专科建设方面做了些探索。通过对亚专科进行短、中、长期的建设规划,重点突破、有序发展亚专业,建立亚专业人才梯队,整合资源建设特色专科,形成专业品牌和拳头产品;各个亚专科通过资源共享、团结协作,全面提升眼科综合专业诊疗水平,以更高效、更规范的医疗技术,让更多患者获益。%The paper makes some explorations of the construction of ophthalmology subspeciality in order to further en-hance the innovation ability and core competiveness of ophthalmology in the prefecture-level hospitals, and establishes the talent team of subspeciality, builds the characteristic specialty by integrating resources and forms a specialized brand and key products by short-term, mid-term and long-term construction plans of subspeciality and breaking through and develop-ing the subspeciality in an orderly manner, and various subspecialities comprehensively improve the diagnosis and treatment levels of ophthalmology comprehensive speciality in order to benefit more patients by more efficient and standardized medi-cal technologies and resource sharing and team work.

  15. Clinical competence training of post-graduate students with professional degree in ophthalmology%眼科学专业学位研究生临床能力的培养

    Institute of Scientific and Technical Information of China (English)

    傅涛; 彭晓燕; 潘志强

    2010-01-01

    提高临床综合分析能力和掌握科学临床思维方法是眼科学专业学位研究生临床能力 培养的关键.首都医科大学附属北京同仁医院眼科学教研室根据眼科学专业学位研究生的特点,制定了切实可行的临床能力培养方案,即开展"入科培训",细化学习目标,坚持采用实际病例教学,强化鉴别诊断,定期组织病例讨论,重视眼科手术基本功训练,建立完善考核制度等,使眼科学专业学位研究生在较短的临床轮转中达到高年住院医师规范化培训后的水平.%It is crucial to enhance the comprehensive capabilities of clinical analyzing and to master the scientific methods of clinical thinking for the post-graduate students with professional degree of ophthalmology. According to their characters, specific training programs were set up in focusing on the fundamental training in ophthalmology and the refinement of learning objectives. The key measures included adopting actual cases in teaching, enhancing differential diagnosis, organizing case discussions at regular intervals , emphasizing on basic skills training in surgery, and improving the examination system. Through the above mentioned training, the clinical skills of post-graduate students with professional degree of ophthalmology could be increased rapidly during the period of rotation, reaching the standard of senior residents.

  16. 重视整合医学在综合医院眼科中的发展%Development of Ho listic integrated medicine in ophthalmology in general hospitals in China

    Institute of Scientific and Technical Information of China (English)

    孙世龙; 陈鹏; 杨潇远

    2015-01-01

    Sub-division within the field of ophthalmology has advanced the practice of eye health care.However,eye is not an isolated organ and the physiopathogenesis of eye diseases involves all organs of the human body.At present,subspecialization in ophthalmology makes eye doctors focus too much on the eye but often ignore the importance of other organs in the diagnosis and treatment of eye diseases .This paper aims to update the theory and knowledge of Holistic Integrated Medicine , review the recent development in integrated medicine and discuss why it is important to take the whole person ( body, mind, and spirit ) including all aspects of lifestyle into account and how to combine conventional and alternative therapies in the practice of ophthalmology in order to improve patient care .%虽然眼科亚专科分类的细化促进了眼科学的发展,但是眼球不是一个孤立的器官,多种眼科疾病的发生与全身系统的生理功能有着密切联系。目前的眼科亚专科模式使得眼科医师将过多的精力集中于眼球,而忽略了整体。笔者借助整合医学的理念,将该理论与临床实践紧密结合,并整合其他临床学科围绕眼科成立各整合眼科学分支,旨在为不同疾病的患者提供综合治疗,以期达到最佳的治疗效果,从而推动整合医学在眼科学科的发展。

  17. To strengthen the education on basic knowledge and skills of neuro-ophthalmology%加强神经眼科基础知识和基本技能的教育

    Institute of Scientific and Technical Information of China (English)

    张晓君; 王宁利

    2011-01-01

    Basic knowledge and skills are cornerstone of the diagnosis and treatment of neuroophthalmology diseases in ophthalmology practice. Due to the interdisciplinary features of neuroophthalmology,neuro-anatomy,neuro-physiology related to eyes,neuro-image and neuro-electrodiagnosis,these should be included in the education for the ophthalmologist.Special attention should be paid to training on capability of logically thinking in neuro-ophthalmology.Multiple ways can be used for the education of ophthalmologists and neurologists for the enhancement of basic knowledge and skills of neuro-ophthalmology in China.%掌握神经眼科基础知识和基本技能是眼科医师在临床实践中正确诊治神经眼科相关疾病的基础.鉴于神经眼科疾病的学科交叉性,其基础知识和基本技能包括眼相关神经解剖、神经生理以及对于神经影像和神经电生理等重要辅助检查手段的正确理解和应用.特别应该强调的是建立正确的诊断思路对于神经眼科疾病诊治的重要性.采用多种途径,加强神经眼科基础知识和基本技能的教育在我国具有非常重要的意义.

  18. Importance of clinical trial design and standardized implementation in ophthalmology%重视眼科临床试验的设计和实施管理

    Institute of Scientific and Technical Information of China (English)

    许迅

    2013-01-01

    临床试验是一种非常重要的医学研究方法,是转化医学的桥梁,其结果常常作为制定临床诊疗指南的科学依据.目前我国虽已在开展眼科临床试验方面积累了较多经验,但试验方案设计的科学性、规范性、伦理性仍存在一些问题,影响了研究结果的真实性和可靠性.因而,重视眼科临床试验的设计和实施管理是今后眼科临床试验的目标和发展方向.临床试验的设计应根据试验目的,遵循国际通用的伦理学准则和设计原则,重视随机化、盲法和对照设置,实施中应注意人员培训、管理和监察,尽可能减少方案偏离的发生和保证数据真实性.%Clinical trial is an important medical research method,as well as the bridge of translational medicine.The results of scientific evidences are useful to make clinical practice guidelines.At present,much experience of carrying out ophthalmology clinical trials has been obtained and achieved,but there are still some scientific,practical and ethical problems to be solved,because of their impact on the authenticity and reliability of the results.Therefore,attaching great importance to design of the clinical research and implement of the standardization would be the goal and the development direction.Clinical trial design rely on objective,follow international design principles on the ethics,randomization,blinding and placebo setting.During the trial implementation,personnel training,project management and monitoring would help to reduce protocol deviation and ensure data authenticity.

  19. Comparative study of ophthalmological and serological manifestations and the therapeutic response of patients with isolated scleritis and scleritis associated with systemic diseases

    Directory of Open Access Journals (Sweden)

    Jacqueline Martins de Sousa

    2011-12-01

    Full Text Available INTRODUCTION: Scleritis is a rare, progressive and serious disease, the signs of which are inflammation and edema of episcleral and scleral tissues and is greatly associated with systemic rheumatoid diseases. PURPOSE: To perform a prospective and comparative study between ophthalmologic manifestations, serologic findings and therapeutic response of patients with isolated scleritis and scleritis associated with systemic rheumatoid disease. METHODS: Thirty-two outpatients with non-infectious scleritis were studied, from March 2006 to March 2008. The treatment was corticoid eye drops associated with anti-inflammatory agents, followed by systemic corticoids and immunosuppressive drugs if necessary, was considered successful after six months without scleritis recurrence. RESULTS: Fourteen of 32 patients had scleritis associated with systemic rheumatoid disease, of which nine had rheumatoid arthritis, two systemic lupus erythematosus, one Crohn's disease, one Behçet's disease and one gout. There were no difference in relation to involvement and ocular complications, there was predominance of nodular anterior scleritis and scleral thinning was the most frequent complication. The scleritis associated with systemic rheumatoid disease group had 64.3% of autoantibodies, versus 27.8% among those with isolated scleritis and this difference was statistically significant. In the isolated scleritis group 16.7% used anti-inflammatory, 33.3% corticosteroids, 27.8% corticosteroids with one immunosuppressive drug, 5.5% two immunosuppressive drugs, 16.7% corticosteroids with two immunosuppressive drugs and 33.3% pulse of immunosuppressive drugs, there was remission in 88.9%. In the scleritis associated with systemic rheumatoid disease group 7.1% used anti-inflammatory, 7.1% corticosteroids, 50% corticosteroids with one immunosuppressive drug, 7.1% two immunosuppressive drugs and 22.2% pulse of immunosuppressive drugs, 100% had treatment success. CONCLUSION

  20. Computer-assisted 3D design software for teaching neuro-ophthalmology of the oculomotor system and training new retinal surgery techniques

    Science.gov (United States)

    Glittenberg, Carl; Binder, Susanne

    2004-07-01

    Purpose: To create a more effective method of demonstrating complex subject matter in ophthalmology with the use of high end, 3-D, computer aided animation and interactive multimedia technologies. Specifically, to explore the possibilities of demonstrating the complex nature of the neuroophthalmological basics of the human oculomotor system in a clear and non confusing way, and to demonstrate new forms of retinal surgery in a manner that makes the procedures easier to understand for other retinal surgeons. Methods and Materials: Using Reflektions 4.3, Monzoom Pro 4.5, Cinema 4D XL 5.03, Cinema 4D XL 8 Studio Bundle, Mediator 4.0, Mediator Pro 5.03, Fujitsu-Siemens Pentium III and IV, Gericom Webgine laptop, M.G.I. Video Wave 1.0 and 5, Micrografix Picture Publisher 6.0 and 8, Amorphium 1.0, and Blobs for Windows, we created 3-D animations showing the origin, insertion, course, main direction of pull, and auxiliary direction of pull of the six extra-ocular eye muscles. We created 3-D animations that (a) show the intra-cranial path of the relevant oculomotor cranial nerves and which muscles are supplied by them, (b) show which muscles are active in each of the ten lines of sight, (c) demonstrate the various malfunctions of oculomotor systems, as well as (d) show the surgical techniques and the challenges in radial optic neurotomies and subretinal surgeries. Most of the 3-D animations were integrated in interactive multimedia teaching programs. Their effectiveness was compared to conventional teaching methods in a comparative study performed at the University of Vienna. We also performed a survey to examine the response of students being taught with the interactive programs. We are currently in the process of placing most of the animations in an interactive web site in order to make them freely available to everyone who is interested. Results: Although learning how to use complex 3-D computer animation and multimedia authoring software can be very time consuming and

  1. PREVALENCE OF REFRACTIVE ERROR, STRABISMUS AND AMBLYOPIA AMONG CHILDREN WITH NORMAL DEVELOPMENT OR GLOBAL DEVELOPMENTAL DELAY/INTELLECTUAL DISABILITY ATTENDING OPHTHALMOLOGY OPD AT KLES HOSPITAL, BELAGAVI- A RETROSPECTIVE STUDY

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    Smitha K. S

    2017-04-01

    Full Text Available BACKGROUND Global developmental delay/intellectual disability are on a rise in children in the present time. Ocular and visual anomalies are frequently associated with it of which refractive errors are the most frequent. This if goes unnoticed leads to strabismus and amblyopia. MATERIALS AND METHODS This study aims to assess the prevalence of refractive error, strabismus and amblyopia among children with normal development or global developmental delay/intellectual disability attending ophthalmology OPD at KLES Hospital, Belagavi. Case records of all 200 new patients less than or equal to 12 years of age group who attended KLES, Dr. Prabhakar Kore Hospital between January 2015 and December 2015 were retrospectively reviewed. RESULTS The male:female ratio was 1.22:1. Out of the total evaluated 200 cases, 130 cases were with normal development and 70 with GDD/ID. Refractive errors were 85%, whereas the cases of amblyopia was 45.50% and strabismus 39.50%. Amblyopia with refractive error having GDD/ID was stastically significant as compared to amblyopia with refractive error having normal development (p=0.001. CONCLUSION Refractive error was the most common ocular disorder seen. Refractive error with amblyopia is more in children with GDD/ID as compared to normal children. Owing to the high percentage of visual anomalies, ophthalmological referral becomes essential in children with developmental anomalies.

  2. 加强学科交叉促进我国神经眼科学的发展%To strength interdisciplinary for the development of neuro-ophthalmology in China

    Institute of Scientific and Technical Information of China (English)

    王宁利

    2010-01-01

    Neuro-ophthalmology is an interdisciplinary field. Promoting the development of neuroophthalmology in China by interdisciplinary is the current trend. With the rapid development of the related disciplines, we should grasp the research hotspots correctly and focus on the oriented research. The cuttingedge research results should be introduced and the innovative teams should be built up. It will be greatly beneficial for the development of the neuro-ophthalmology in China by boosting the combination of neuroophthalmology and the cross subjects.%神经眼科学是一门交叉性极强的学科,通过交叉学科的发展推动我国神经眼科的发展是当今发展的趋势.在相关学科不断取得新的突破的同时,加强神经眼科与其他学科的交叉联合,正确把握学科交叉热点,引进前沿研究成果,组建创新型团队,突出导向性研究,对促进我国神经眼科快速发展大有裨益.

  3. Listas de comprobación de las habilidades prácticas de la asignatura Oftalmología Checking lists of the practical abilities of the Ophthalmology subject

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    Georgina Saint-Blancard Morgado

    2001-06-01

    Full Text Available En la asignatura Oftalmología los procederes diagnósticos se basan en exámenes instrumentados que requieren un entrenamiento especial y sistemático para la adquisión de las habilidades. La evaluación sistemática y el examen práctico, basados en la observación, constituyen las vías fundamentales para constatar su apropiación. Con el fin de hacer más certeros los juicios y unificar criterios, se diseñaron sobre la base de la teoría de la actividad, listas de comprobación para 3 de las habilidades que se incluyen en el programa de la asignatura Oftalmología en 5to. año de Medicina. Se incluyen además los criterios de calificación.In the Ophthalmology subject the diagnostic procedures are based on tests designed in such a way that require a special and systematic training for the acquisition of abilities. The systematic evaluation and the practical test, which are based on obervation, are the fundamental ways to verify their suitability. In order to make judgments more accurate and to unify criteria, checking lists for 3 of the abilities included in the program of Ophthalmology subject in the 5th year of Medicine were made on the basis of the theory of activity. The marking criteria were also taken into consideration

  4. To Further the Near-Vision Visual Acuity Tests (2) : The Necessity of Near-Vision Visual Acuity Testing from the Results of a Detailed Examination of Children's Visual Acuity Carried Out in an Ophthalmology Clinic(Special Issue Dedicated to Professor HASHIUCHI Takeshi)

    OpenAIRE

    高橋, ひとみ; 川端, 秀仁; 衞藤, 隆

    2014-01-01

    After carrying out far-vision visual acuity tests, near-vision visual acuity tests, refraction tests, and ciliary muscle function tests at A elementary-school, we stressed the need for school medical checkups to be followed up by consultation at an ophthalmology clinic in the case of children with poor far-vision visual acuity, poor near-vision visual acuity, or eye control dysfunction. 155 children were seen in an ophthalmology clinic and given a detailed examination. We carried out an in-de...

  5. Clinical characteristics of 679 cases from an Ophthalmologic Emergency Department at night%夜间眼科急诊679例临床分析

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    杜君; 周素梅; 刘玥; 郑广瑛; 张凤妍; 雷方; 尹玉

    2016-01-01

    Objective To investigate the clinical characteristics of patients in the Ophthalmologic Emergency Department (OED) at night.Methods The records of 679 patients attending to the OED of the First Affiliated Hospital of Zhengzhou University at night (from 5:30 p.m.to 8:00 a.m.of the next morning) were collected from Aug.2012 to Jul.2013.The gender,age,career,visiting time,initial diagnosis,emergency treatment and visual outcome were analyzed.Results In this study,for the patients younger than 60 years old,there were more male patients than female.For the patients more than 60 years old,there were more female patients than the male.Peasants(33.3%) and workers(29.9%) accounted for the majority proportion of the patients,followed by preschool children(17.5%) and students(15.0%).The most common diseases in OED were ocular trauma(83.9%),ocular surface inflammation (13.4%) and acute primary angle closure glaucoma(PACG,2.2%).There was significant difference between male and female(X2 =41.943,P =0.000) in those three types of diseases.The proportion of patient admitted to the OED were 54.8%,36.1%,9.1% in the period of 22:00-03:00 o'clock,17:30-22:00 o'clock and 03:00-08:00 o'clock,respectively.Among the 679 cases,563 cases(82.9%) required hospital admission,508eyes of 487 cases (63.6%) underwent emergent operations,in which 41 eyes of 33 cases (5.1%) were treated by multiple combined operations.The final best corrected visual acuity (BCVA) of less than 0.05occurred in 38 eyes (6.0%),0.05 ~0.25 in 176 eyes (27.6%),and ≥0.3 in 423 eyes (66.4%).Conclusion Ocular trauma,ocular surface inflammation,and acute PACG are the three main diseases in OED from 17:30 to 08:00 of the next day.The largest number of patients visiting OED was in the period of 22:00 ~03:00 o'clock.Most of the patients need emergent surgeries.%目的 了解夜间眼科急诊患者的临床特点.方法 2012年8月至2013年7月每天17:30到次日早上08:00间

  6. Avaliação oftalmológica em pacientes com AIDS e neurotoxoplasmose Ophthalmological evaluation of patients with AIDS and neurotoxoplasmosis

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    Jane Mary Alves

    2010-02-01

    -phase neurotoxoplasmosis. METHODS: A prospective study of case series type was developed, including 70 patients of both sexes and ages ranging from 20 to 63 years who were admitted to the wards of three public hospitals in the city of Recife, Pernambuco, Brazil, from January to October 2008, with diagnoses of AIDS and neurotoxoplasmosis determined according to the criteria of the Centers for Disease Control and Prevention (1992. The patients were characterized by a first episode of neurotoxoplasmosis (65; 92.9% or recurrence (5; 7.1%, unawareness of having AIDS (23; 32.9%, mean T CD4+ count of 139.8 ± 3.04 lymphocytes/mm³ and mean viral load of 137,080 ± 39,380 copies/ml. All patients underwent ophthalmological examination consisting of ocular inspection, gauging of visual acuity, investigation of ocular extrinsic muscle function and fundoscopy using a binocular indirect ophthalmoscope (model OHM 3.5 Eyetec® and external lens of 20 diopters (Volk®. RESULTS: The findings consisted of retinal cotton-wool spot exudates (8.6%, slight diffuse arteriolar constriction (8.6%, retinochoroiditis scars characteristic of ocular toxoplasmosis (5.7%, atrophy of retinal pigment epithelium (2.9%, retinal detachment (2.9%, increased papillary excavation (1.4%, retinal peripheral degeneration (1,4%, macroaneurysm (1.4%, bilateral papilledema (1.4% and vitreous-retinal traction (1.4%. CONCLUSIONS: Patients with AIDS and neurotoxoplasmosis may present fundoscopic abnormalities characteristic of ocular toxoplasmosis, either in active or in scar form, related to HIV or even to other opportunist or systemic diseases, which can be of great aid for integral treatment of patients by a multiprofessional team.

  7. Application of 3D simulation technology in Ophthalmology & Optometry teaching%三维仿真技术在眼视光教学中应用的研究进展

    Institute of Scientific and Technical Information of China (English)

    田甜; 郭长锋

    2013-01-01

    三维仿真技术是指利用计算机技术生成的一个逼真的,具有视、听、触、味等多种感知的虚拟环境,用户可以同虚拟环境中的实体相互作用的一种多媒体技术,其以生动形象的虚拟现实(VR)技术在医学教育方面受到越来越多的重视,也为眼视光学的教育和教学提供了新的发展平台.笔者主要介绍三维仿真模型、三维动画技术、虚拟现实技术在眼视光学和眼科学教学中的具体应用和发展现状.%The three-dimensional simulation technology refers to the technology which can use the computer technology to generate a realistic virtual environment with visual,hearing,touch,taste,and other perception.Users can have interaction with entity in the virtual environment.With its very vivid virtual reality (VR) technology,3D simulation technology has gained more and more attention and provided a new development platform for ophthalmology and optometry teaching.This paper mainly introduced teaching the present development situation and the specific application of the 3D simulation model,3D animation technology,virtual reality technology in optometry and ophthalmology.

  8. 综合打分法在同仁医院眼科人才考核中的应用%The application of comprehensive scoring system at the ophthalmology department of Tongren Hospital

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    杜敬毅; 韩德民

    2011-01-01

    同仁医院眼科作为国家级重点学科,在评聘分开的小环境中,总结出一套较为科学、实用、可操作性较强的重点学科专业技术人员的考核办法是管理工作的当务之急.通过在日常管理工作中总结出来的综合打分法,运用该法对重点学科的高级职称人员的各项工作实施量化考核,以此来打造公开、公平和透明的竞争环境,促进重点学科各项工作的开展,打造有竞争力的人才队伍,提高公立医院的核心竞争力.%As a national key discipline. the Ophthalmology Department of Beijing Tongren Hospital this paper points out that competition in the market of ophthalmology is about competing for the best human resource. has been seeking a method that allows it to evaluate the practicing professionals in a more scientific, functional and feasible way against its policy of separating appointment from assessment. This paper discusses the “comprehensive scoring” system that the author has developed and applied in her daily managerial experiences. At the center of comprehensive scoring are quantitative evaluation of senior employees, and open and fair competition. Comprehensive scoring system has been proved effective in streamlining the management of a national key discipline, building competitive professional teams and improving the core competence of public hospitals.

  9. Progress of nano -controlled releasing system on ophthalmologic administration%纳米控释系统在眼科给药方面应用的研究进展

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    王淑荣; 王选重; 崔学军; 张妍

    2015-01-01

    ?The ophthalmic application of nanometer materials are mainly concentrated on controlled releasing systems. Due to the unique properties of nanometer materials, it has great advantages in carrying ophthalmic drugs compared with the conventional method, mainly in higher bioavailability and fewer side effects.As a result, nano-controlled releasing system has good application prospect in ophthalmology. At present, a variety of different types of nano -controlled releasing systems have been used to enhance the efficiency of the ophthalmic drugs, including nanomicelle, nanoparticles, nanosuspensions, liposomes, dendrimers, etc. In this paper, the research progress as well as the application of nano-controlled releasing system on ophthalmologic administration is reviewed.%纳米材料在眼部给药方面的应用主要集中在纳米控释系统,由于纳米材料的特有属性,使用纳米材料运载治疗眼部疾病的药物与传统给药方式相比具有很大的优越性,主要表现在药物的纳米制剂具有更高的生物利用率和更低的副作用。因此纳米控释系统在眼科具有良好的应用前景。目前,已经有多种不同类型的纳米控释系统被用于提高眼部给药效率的研究,包括纳米胶束、纳米颗粒、纳米混悬剂、脂质体和树突状分子等。本文就纳米控释系统在眼科给药方面应用的研究进展作一综述。

  10. 眼科门诊感染相关因素及防控措施探讨%Discussion on the related factors and prevention and control measures of ophthalmology outpatient department

    Institute of Scientific and Technical Information of China (English)

    邵亚群

    2015-01-01

    目的:探讨在眼科门诊工作中易引发感染的影响因素并采取相应的防控措施。方法:通过对诊室环境,检查设备消毒及医患人员自我保护意识等环节展开讨论,分析引发感染因素。结果:针对易引发感染的相关环节,采取“一医一患”、“一患一洗手”及“一用一灭菌”措施,加强医患人员自我保护意识,有效避免相关感染的发生。结论:通过对眼科门诊易引发感染关键环节的有效防控,既加强了防控力度又取得了良好的社会效益。%Objective: To explore the factors that can easily lead to infection in the outpatient department of ophthalmology, and take corresponding preventive measures. Methods: The consulting room environment, cross infection, inspection equipment disinfection and medical personnel and medical personnel to protect themselves from the lack of self-protection awareness and other aspects of the discussion, analysis of related factors causing infection. Results: In view of easily lead to infection of the link, take"a doctor and a patient","for a patient of a hand washing","one with a sterilization", strengthen medical personnel ego to protect consciousness etc. prevention and control measures, effectively avoid the occurrence of infection. Conclusion:Through the effective prevention and control of the key links in the outpatient department of ophthalmology, it can strengthen the prevention and control, and the good social benefits.

  11. Application of PDCA cycle in improving the safety management quality of ophthalmologic operation%运用PDCA循环法提高眼科手术安全管理质量

    Institute of Scientific and Technical Information of China (English)

    吴华; 刘琼; 张丽

    2015-01-01

    目的:研究PDCA循环法在眼科手术安全管理质量中的应用效果三。方法:选取2015年1月~2015年6月在我院眼科工作的护士26名,2015年2月开始运用PDCA循环法对26名护士进行手术安全管理培训,持续进行5个月。由质控小组考核培训前后安全隐患得分情况。结果:2015年1月与2014年1~6月安全隐患改善率比较差异无统计学意义(P>0.05);2015年2~6月安全隐患改善率分别为61.4%、75.0%、90.9%、93.2%、95.5%显著高于2014年1~6月及2015年1月,差异有统计学意义(P<0.05);培训后护理总满意度87.5%显著高于培训前71.3%,差异有统计学意义(P<0.05)。结论:PDCA循环管理法临床应用效果好,值得推广。%Objective To study the application effect of PDCA cycle in the safety management quality of ophthalmologic operation. Methods 30 nurses working in the department of ophthalmology in the hospital during January 2014 to June 2015 were selected and all ofthem were trained with PDCA cycle for operative safety management from January 2015, lasting for 6 months. The condition of potential safety hazard was evaluated by the quality control group before and after training. 80 cases of ophthalmologic patients were respectively selected before and after training. The occurrence of complications and nursing satisfactory degree were observed and compared.Results There was no statistically significant difference in the improvement rates of potential safety hazard in January 2015 and January to June 2014(P<0.05). The improvement rates of potential safety hazard during February to June 2015 were 61.4%, 75.0%, 90.9%, 93.2% and 95.5%, respectively which were significantly higher than those during January to June 2014 and January 2015, and the difference was statistically significant (P<0.05). The total nursing satisfactory degree after training was 87.5% which was significantly higher than 71.3%before training, and the difference

  12. Problemas oftalmológicos mais freqüentes e desenvolvimento visual do pré-termo extremo Frequent ophthalmologic problems and visual development of preterm newborn infants

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    Rosa Maria Graziano

    2005-03-01

    Full Text Available OBJETIVO: Revisar conceitos do desenvolvimento visual e principais alterações oculares do recém-nascido prematuro. Salientar a importância do exame oftalmológico preventivo e tratamento precoce das doenças oculares. FONTE DOS DADOS: Dados de literatura. SÍNTESE DE DADOS: A visão é um dos mais importantes sentidos no desenvolvimento físico e cognitivo normal da criança. Em recém-nascido prematuro, as funções visual, motora e cognitiva, quando comparadas às de crianças de termo em idade escolar, são prejudicadas. Isto se deve mais à imaturidade do sistema nervoso central do que a lesões localizadas em estruturas oculares e/ou corticais. A retinopatia da prematuridade, o estrabismo e os erros de refração são as principais alterações oftálmicas secundárias à prematuridade descritas na literatura. A retinopatia da prematuridade é uma das principais causas de cegueira prevenível na infância. Calcula-se que, em média, 562 crianças fiquem cegas por ano no Brasil, um custo socioeconômico alto, principalmente por se tratar de uma doença passível de tratamento. Muito pode ser feito pela criança com deficiência visual; programas de estimulação visual precoce permitem que a criança possa ter uma integração maior com seu meio. CONCLUSÕES: Recomenda-se que todo recém-nascido prematuro com p OBJECTIVES: To review the concepts of visual development and the major ocular abnormalities in preterm newborns. To emphasize the importance of preventive ophthalmologic examination and early treatment of ocular disorders. SOURCES OF DATA: A review of published data. SUMMARY OF FINDINGS: Vision is one of the most important senses in the normal physical and cognitive development of children. Schoolchildren who were born preterm have impaired visual, motor and cognitive functions when compared to those of children born full term. This is more a consequence of central nervous system immaturity than of localized injuries to ocular and

  13. Assessment of the prevalence of refractive eye error and IOP during pregnancy and after delivery in patients referred to ophthalmology clinic of Boo-Ali Hospital of Qazvin in 1387

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    Mohammad Khalaj

    2009-01-01

    Full Text Available (Received 30 Jan 2010, 2010 ; Accepted 25 April, 2010AbstractBackground and purpose: Many pregnant women some of whom also suffer from refractive errors and use eyeglasses attend eye clinics The aim of this study was to assess the prevalence of refractive eye errors and changes in IOP, during pregnancy and after delivery among patients referred to ophthalmology clinic of Boo-Ali Hospital of Qazvin.Materials and methods: The study was conducted at eye clinic of Boo-Ali Hospital in Gazvin- Iran. A total of 150 pregnant women aged 17 to 38 years (mean 24.76 ± 4.61 were treated by ophthalmologist in three stages (16- and 32- week of pregnancy and 4 months after childbirth. Initially, all pregnant women were visited by a gynecologist and then they were referred to the ophthalmology clinic. The visual acuity was determined using chart Snellen from a distance of 6m and then refractive errors were measured by static retinoscopy and autorefractometer. Intraocular pressure was measured using air-puls noncontact tonometer in three stages.Results: In the first stage (16-week of pregnancy, hyperopia was seen in 12 patients (%8, myopia in 104 patients (%69.3, astigmatism in 26 patients (%17.3 and 8 patients (%5.3 were normal. The results of the second stage (32-week of pregnancy showed that 3 patients (%2 were hyperopia, 143 patients (%95 myopia, 2 patients (%1.3 astigmatism and 2 patients (%1.3 were normal. Four months after childbirth, 5 patients (%3.3 were hyperopia, 129 patients (%86 myopia, 13 patients (%13.7 astigmatism and 3 patients (%2 normal. The estimated relative risk of myopia was increased significantly in the second stage. The patients' IOP in the first stage was higher than the second stage and this difference was statistically significant (P<0.05.Conclusion: The results of this research showed that there is a significant relationship between pregnancy and myopia. IOP was reduced during pregnancy and return to the normal level after delivery

  14. The Application Effect of Clinical Pathway Teaching Method in Ophthalmology%临床路径教学法在眼科教学中的效果观察

    Institute of Scientific and Technical Information of China (English)

    吴星; 王凤翔

    2016-01-01

    Objective To explore the application effect of clinical pathway teaching method in ophthalmology.Methods 50 students were divided into experimental group and control group according to different teaching methods in our hospital from January 2014 to June 2016. 25 students in each group. The students of experimental group accepted the clinical pathway teaching method, and the students of control group accepted the traditional teaching method. At the end of study, the scores of the students, including their theoretical knowledge examination and clinical case diagnosis examination, were analyzed by statistics. The satisfaction degree of the students to the different teaching methods was also investigated. ResultsThe scores of the students accepting clinical pathway teaching method were higher than the students accepting the traditional teaching method. The students were more satisfied with the clinical pathway teaching method (P<0.05).Conclusion Compared to the traditional method, the clinical pathway method can more improve the teaching quality in ophthalmology.%目的探究眼科教学中临床路径教学方法的应用效果。方法选取我院2014年1月~2016年6月在眼科学习的研究生、进修生和规培生50名,按教学方式的不同随机分为实验组和对照组各25名。实验组给予临床路径式教学,对照组给予传统方式教学,对两组学习结束后的理论知识考核成绩、临床病例诊断考核成绩和带教方法满意度进行调查。结果无论是在理论知识考核、临床病例诊断考核还是带教方法上,临床路径教学组都高于传统教学方式组(P<0.05)。结论在眼科应用临床路径教学法进行教学,相比传统的教学方法,能更好地提高教学质量。

  15. Experience in clinical teaching of ophthalmology to students of 7-year medical education program%眼科七年制医学生临床带教体会

    Institute of Scientific and Technical Information of China (English)

    葛轶睿; 黄振平

    2011-01-01

    Based on the characteristics of the students of 7-year medical education program in ophthalmology, we developed an " Integration-of-Five" mode of teaching, covering clinical training, ward training, comprehensive training, expanding training, and scientific research training, aiming to cultivate their abilities of analyzing and solving problems on their own, improve their basic clinical skills, and lay a solid foundation for their future clinical work.%针对七年制眼科研究生的特点,采用门诊训练、病房训练、综合性训练、拓展性训练、临床科研训练五位一体的临床带教模式,锤炼研究生独立分析问题、解决问题的能力,提高临床基本技能,为其以后临床工作打下坚实的基础.

  16. Regression models in the determination of the absorbed dose with extrapolation chamber for ophthalmological applicators; Modelos de regresion en la determinacion de la dosis absorbida con camara de extrapolacion para aplicadores oftalmologicos

    Energy Technology Data Exchange (ETDEWEB)

    Alvarez R, J.T.; Morales P, R

    1992-06-15

    The absorbed dose for equivalent soft tissue is determined,it is imparted by ophthalmologic applicators, ({sup 90} Sr/{sup 90} Y, 1850 MBq) using an extrapolation chamber of variable electrodes; when estimating the slope of the extrapolation curve using a simple lineal regression model is observed that the dose values are underestimated from 17.7 percent up to a 20.4 percent in relation to the estimate of this dose by means of a regression model polynomial two grade, at the same time are observed an improvement in the standard error for the quadratic model until in 50%. Finally the global uncertainty of the dose is presented, taking into account the reproducibility of the experimental arrangement. As conclusion it can infers that in experimental arrangements where the source is to contact with the extrapolation chamber, it was recommended to substitute the lineal regression model by the quadratic regression model, in the determination of the slope of the extrapolation curve, for more exact and accurate measurements of the absorbed dose. (Author)

  17. How to guide graduate thesis of ophthalmology writing more perfect%如何指导眼科研究生毕业论文写作更完美

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    李建军; 刘丽娟; 王爽

    2012-01-01

    Graduate thesis writing in ophthalmology usually exist some editing problems, such as in mixture of Chinese-English punctuation, confusing and misuse of Chinese characters and phrases, non-self-evident of pictures and forms, errors of reference recording. We carried out editing seminars for graduates, graduate internships into the editorial office of journals, and thesis review and modify trials among inter-graduates, which greatly improve the level of graduate thesis writing.%研究生毕业论文写作中通常存在较多的编辑问题,诸如中英文标点符号混用,易混淆汉字及词组误用,图片表格不能自明,参考文献著录错误等.通过在眼科学研究生中开展编辑知识专题讲座、研究生到专业杂志编辑部实习、研究生之间互相审修等方法,显著改善了研究生毕业论文的写作水平.

  18. Importância do exame oftalmológico na doença de von Hippel-Lindau The importance of the ophthalmological examination in von Hippel-Lindau disease

    Directory of Open Access Journals (Sweden)

    Ricardo Evangelista Marrocos de Aragão

    2009-08-01

    Full Text Available Von Hippel-Lindau (VHL é uma síndrome tumoral autossômica dominante. Esses tumores incluem hemangioblastoma da retina e sistema nervoso central (CSN, carcinoma de células renais, feocromocitoma, tumores de pâncreas, cistoadenoma de rins, pâncreas e epidídimo. Os sintomas mais comuns são perda da visão, aumento da pressão intracraniana, déficits neurológicos, aumento da pressão arterial sistêmica paradoxal e dor local. Relatamos o caso de um paciente com perda de visão e história de hemangiomas cerebelares cujo diagnóstico de VHL foi feito após exame oftalmológico.Von Hippel-Lindau (VHL disease is an autossomical, dominant inherited tumour syndrom. These tumours may include haemangioblastoma in the retina and central nervous system (CNS, renal cell carcinoma, phaeochromocytoma, islet cell tumours of the pancreas, cystadenoma in the kidney, pancreas, and epididymis. The most common symptoms include: loss of vision, raised intracranial pressure, neurological deficits, paroxysmal raised blood pressure and local pain. We report herein a 29-year-old man with visual loss and cerebellar haemangioblastoma that despite neurological manifestations the diagnosis of VHL was established after the ophthalmological examanination.

  19. An etiological analysis of Chinese neuro-ophthalmology disorders in child and adolescent inpatients%儿童及青少年神经眼科住院患者病因分析

    Institute of Scientific and Technical Information of China (English)

    李星仪; 张秀兰; 王伟; 魏世辉

    2013-01-01

    目的 了解儿童及青少年神经眼科住院患者的病因及病变定位.方法 对2009年10月至2011年7月期间,在解放军总医院神经眼科病房住院的儿童及青少年神经眼科患者(<18岁)的病历资料进行回顾性分析,分类统计病因及病变定位.结果 神经眼科住院儿童及青少年患者共129例,视觉传入系统受累共120例(包括视觉传入传出系统同时受累共4例),其中视神经疾病93例,占视觉传入系统受累患者的77.50%,占全部住院患者的72.09%;眼部运动传出系统受累13例(包括视觉传入传出系统同时受累共4例).其中眼球运动障碍为主,共9例,占传出系统受累患者的69.23%,占全部住院患者的6.98%.单眼发病53例,双眼发病76例,共累及205只眼.病因明确者118例,占总病例数91.47%.结论 在儿童及青少年神经眼科住院患者中,视神经是最常见的受累部位.其中原发性脱髓鞘性疾病、外伤性视神经病变及遗传或先天性视神经病变是视神经疾病最常见的原因.%Objective To investigate the etiology of pediatric neuro-ophthalmology disorders in China.Methods Retrospective case series.Clinical data of children and adolescents <18 years suffered from neuro-ophthalmology diseases who hospitalized in the Department of Neuro-ophthalmology,General Hospital of PLA from October 2009 to July 2011 was reviewed.Results Totally 129patients were recruited to study.The visual afferent system of 120 cases was injured including 93cases with optic neuropathy,which accounted for 77.50% of the patients with visual afferent system injured and 72.09% of the total hospitalized patients.The efferent nerve system of 13 cases was injured.The ocular motor system was affected in 9 cases,which accounted for 69.23% of the patients with efferent nerve system affected and 6.98% of the total hospitalized patients.Unilateral eye was affected in 53 cases,and bilateral eyes were affected in 76 cases

  20. 基于临床教学资源整合的眼科信息化教学探索%Informatized teaching of ophthalmology based on the integrated clinical resources

    Institute of Scientific and Technical Information of China (English)

    桑延智; 刘心; 赵世红; 彭骏; 潘冬艳

    2012-01-01

    针对眼科解剖精细、检查特殊、检诊繁多、手术细微等特点,提出构建网络资源平台,将眼科临床实践中积累的大量图片、视频等教学资料纳入信息化管理,并且进一步开发、收集、整合为优质的临床教学资源,使学生在学习中自主性增强、机动性加大,点面结合及进行模拟训练的一些做法.%In view of the characteristics of ophthalmology such as the eyes subtle anatomy, special examinations, various detection diagnosis and microscopical operations, we proposed constructing a network-based resources platform where teaching materials such as a great number of photos and videos accumulated from daily opthalmological clinical work can be managed and further developed, collected and integrated to become high-quality clinical teaching resources, which gives students a greater autonomy and flexibility in learning and point-whole combination and simulated training.

  1. Condições oftalmológicas de pacientes com síndrome da imunodeficiência adquirida com longo tempo de seguimento Ophthalmologic conditions of aids patients with long-term follow-up

    Directory of Open Access Journals (Sweden)

    Márcia Abelin Vargas

    2007-02-01

    Full Text Available OBJETIVO: Avaliar as condições oftalmológicas atuais de pacientes com síndrome da imunodeficiência adquirida (SIDA, previamente avaliados por oftalmologista, levando em consideração algumas características gerais relacionada com essa doença. MÉTODOS: Estudo observacional de 42 pacientes com SIDA, subdivididos em dois grupos: Grupo I: 8 pacientes com SIDA e diagnóstico prévio de retinite por citomegalovírus; Grupo II: 34 pacientes com SIDA sem retinite por citomegalovírus. Os dados gerais relacionados com a SIDA foram obtidos pela análise dos prontuários médicos. RESULTADOS: A maioria dos pacientes apresentou acuidade visual no melhor olho entre logMAR 0,0 (68,3% e 0,1 (26,9%. Prescrição óptica para longe beneficiou 39,4% dos pacientes do Grupo II mas nenhum dos paciente do Grupo I. Presbiopia foi corrigida em 27,3% no Grupo II e 12,5% no Grupo I. Não foram encontradas manifestações oculares atuais relacionadas a SIDA em nenhum dos grupos. As alterações fundoscópicas encontradas em 10 pacientes foram todas alterações cicatriciais de retinite/retinocoroidite, sendo 7 (16,7% pacientes pertencentes ao Grupo I e 3 (7,1% pacientes pertencentes ao Grupo II. CONCLUSÃO: Dez (24,4% pacientes apresentaram alteração visual decorrente do envelhecimento. Com exceção dos pacientes com cicatrizes prévias de retinite ou retinocoroidite, todos os outros participantes estavam em boas condições oftalmológicas e a maioria dos mesmos se encontrava em recuperação imunológica, devido ao uso da terapia anti-retroviral de alta potência.PURPOSE: To evaluate the ophthalmologic conditions of patients with AIDS, with long-term follow-up, previously evaluated by an ophthalmologist, considering general conditions related with AIDS. METHODS: Observational study of 42 patients with AIDS divided into two groups: Group I: 8 patients with previous AIDS-related cytomegalovirus retinitis, Group II: 34 patients with AIDS without cytomegalovirus

  2. 腺苷及其衍生物在眼科应用的研究进展%Progress in research of adenosine and its biological products in ophthalmology

    Institute of Scientific and Technical Information of China (English)

    于军; 钟一声

    2011-01-01

    腺苷是机体内一种重要的生物活性物质,其广泛存在于细胞内液和细胞外液中。在生理状态下,细胞内外的腺苷浓度较低,但在应激情况下,如炎症、缺血、缺氧、创伤、疼痛等,机体内腺苷浓度会大幅度上升,广泛参与多种病理变化过程。腺苷受体具有A1、A2A、A2B、A3 4种亚型。腺苷通过其受体调控细胞的各种生理功能。目前研究发现腺苷在机体的中枢神经系统、心血管系统、凝血系统等发挥重要作用。近几年来,腺苷在眼部,特别是青光眼、视网膜疾病治疗方面的作用受到广泛关注。腺苷在眼部的作用表现为调节眼压、抑制视网膜新生血管、舒张视网膜血管、调节视网膜神经传导、保护视网膜光感受器和视网膜神经节细胞(RGCs)、抑制炎症反应等。就腺苷和其受体、生物制剂的研究进展及其在眼科的应用前景进行综述。%Adenosine is an important biological substance in the body. It exists extensively in intracellular and extracellular tissues. In physiological condition, adenosine remains at very low level intissue. However, under stress such as inflammation, ischemia, hypoxia, trauma, or pain etc. the adenosine concentration will be elevated dramatically,indicating that adenosine participates in multiple histopathological processes. Adenosine is a natural chemical messenger that binds to four subtypes( A1, A2A, A2B, A3 ) of adenosine receptors and by that, it regulates multiple kinds of physiological functions. Studies found that adenosine plays an important role in the central nervous system, cardiovascular system and coagulation system. In recent years, adenosine has been seen as an attractive option to improve the treatment of glaucoma and retinal diseases. The effects of adenosine in ophthalmology were as follows: adjusting intraocular pressure, inhibiting retinal angiogenesis, dilating retinal blood vessels, regulating retinal

  3. 毛细管气相色谱法测定眼科手术粘弹剂中乳酸含量%Determination of Lactic acid in Ophthalmologic Surgical Viscoelastic Agents by Capillaty Gas Chromatography

    Institute of Scientific and Technical Information of China (English)

    张莉; 文燕; 齐伟明; 王敏珠

    2014-01-01

    采用毛细管气相色谱法测定眼科手术粘弹剂中乳酸的含量。乳酸与甲醇酯化反应后,选用氯仿提取其中酯类物质,进行GC分析。采用DB-Wax毛细管柱(30 mm×0.32 mm,0.5μm),FID检测器,进样口温度为250℃,检测器温度为250℃。采用程序升温,起始温度为70℃,以5℃/min升温至100℃,再以25℃/min升至220℃,保持2 min。在选择的色谱条件下,酯化后的乳酸得到良好的分离,乳酸线性范围为0.0894~1.1652 mg/mL (r=0.9996),检出限为0.15µg/mL。方法的加标回收率为97.8%~98.8%,测定结果的相对标准偏差为1.97%(n=6)。该方法样品前处理简单,干扰少,重现性好,分离效率高,可作为眼科手术粘弹剂中功能成分乳酸质量控制的方法。%The method for the determination of lactic acid in ophthalmologic surgical viscoelastic agent by capillaty gas chromatography was established. After the esterication of lactic acid with methanol, chloroform was used to extract the esterication product for GC analysis. ADB-Wax column (30 mm×0.32 mm, 0.5 µm) and FID were used. The injector and detector temperature was 250℃. Column temperature was controlled by the program:initial temperature of 70℃was raised to 100℃at 5℃/min, then raised to 220℃(2 min) at 25℃/min. Under the optimised conditions, esterification of lactic acid was well separated. Standard addition test results showed that the recoveries were 97.8%-98.8%, the relative standard deviation was 1.97%(n=6). The detection limit was 0.15 µg/mL. This method is simple,fast,sensitive and accurate,and it can be used for mass control of lactic acid content in ophthalmologic surgical viscoelastic agents.

  4. Study on etiologic causes of binocular diplopia in patients with extraocular related diseases in department of ophthalmology%眼科首诊双眼复视患者的眼外相关病因分析

    Institute of Scientific and Technical Information of China (English)

    王珣竹

    2012-01-01

    Objective To explore the etiologic causes of binocular diplopia as the first onset symptom in patients with extraocular related ophthalmic diseases. Methods On the basis of medical history, routine ophthalmologic examination and ocular muscle examination, general check - up and blood biochemical examinations were applied to explore the pathogenic causes. Results The main aetiological cause was vascular disease, then traumatic injury of cranial nerves and abducent nerve palsy were its secondary causes. Conclusion The pathogenic factors of binocular diplopia were complicated, therefore detail clinical data should be correctly collected and necessary diagnostic examinations should be performed for proper diagnosis and treatment.%目的 探讨眼科以双眼复视为首发症状的眼外相关病因的分布情况.方法 根据病史、眼科专科检查、全身相关检查及相关科室检查会诊意见分析病因.结果 68例双眼复视患者中,发病原因中以血管性疾病居多(占32.3%);外伤次之,占16.2%.眼外肌及颅神经受累情况,外展神经麻痹居多24例,占35.3%.结论 双眼复视病因复杂,详细正确的临床资料和必要的辅助检查有助于明确病因.

  5. 基于FPGA的眼科超声数字化中CIC内插滤波器的改进与实现%Improvement and implementation of CIC interpolation filter in ophthalmology ultrasonography digital image based on FPGA

    Institute of Scientific and Technical Information of China (English)

    程春卯; 计建军; 王延群; 杨军; 王晓春; 周盛; 宋学东; 段炳柱

    2010-01-01

    Objective The aim of this study was to improve cascaded integrator comb (CIC) interpolation filter for the enhancement of sampling frequency in the ophthalmology ultrasonagraphy digital imaging system. Methods CIC filter was improved base on the analysis of it and the combined introduction of COSINE and interpolated second-order polynomials(ISOP) filters. Results The modified structures were implemented in field programmable gate array(FPGA) using verilog hardware description language. The algorithm was validated by simulation. Conclusion The results showed that the improved CIC not only had the advantage of high efficiency and saving more resources, but also ameliorated its pass band and stop band. It is applicable in high frequency uhrasonography digital signal processing.%目的 眼科高频超声数字化成像中使用内插滤波器可等效地提高采样率以节约资源.方法 在研究分析了级联积分梳状(CIC)滤波器的基础上,结合运用余弦(COSINE)滤波器和内插二阶多项式(ISOP)滤波器对其进行改进.结果 通过硬件描述语言描述改进后的高效结构,并在现场可编程门阵列(FPGA)中实现,最后通过实验仿真验证该内插变频算法的有效性.结论 改进后的CIC滤波器基本保留了效率和资源节约方面的优势,同时也改善了其通带宽度和阻带衰减特性,能够适用于10 MHz的高频眼科超声信号处理的要求.

  6. Membrane frizzled-related protein gene–related ophthalmological syndrome: 30-month follow-up of a sporadic case and review of genotype-phenotype correlation in the literature

    Science.gov (United States)

    Leaci, Rosachiara; Zenteno, Juan C.; Casubolo, Cristina; Delfini, Elisabetta; Macaluso, Claudio

    2012-01-01

    Purpose To report a new sporadic case of membrane frizzled-related protein gene (MFRP)-related syndrome with a 30-month follow-up, and to review the literature for genotype-phenotype correlation in MFRP mutations. Methods A complete ophthalmological evaluation was performed at presentation and 30 months later, including best-corrected visual acuity test, slit lamp examination, fundoscopy, kinetic perimetry, electroretinography, fundus imaging (color, red-free, and autofluorescence), and morphologic-biometric analysis of the eye structures with an optical biometer, anterior-segment optical coherence tomography, retinal optical coherence tomography, and a confocal scanning laser for optic nerve head study. Polymerase chain reaction amplification of DNA obtained from peripheral blood lymphocytes and nucleotide sequencing of the complete MFRP gene were performed. The literature on cases of posterior microphthalmos and retinitis pigmentosa associated with MFRP mutations was reviewed. Results A 33-year-old female patient presented with posterior microphthalmos, retinitis pigmentosa with patches of retinal pigmented epithelium atrophy and scarce pigment mobilization, foveoschisis, and optic nerve drusen. After 30 months, progression of rod-cone retinal degeneration was detected. One obligate carrier showed a normal eye phenotype. A homozygote mutation in the MFRP gene (c.492delC), predicting a truncated protein (P166fsX190), was identified with genetic analysis. To our knowledge, 17 cases of MFRP-related syndrome have been reported in the literature, including the patient described herein. The phenotype of the syndrome, expressivity, and age of onset varied among and within the affected families. However, all patients sharing homozygous mutation c.492delC (alternatively named c.498delC) showed a complete phenotype (including foveoschisis and optic nerve head drusen), and similar fundus characteristics. Conclusions A new sporadic case of MFRP-related syndrome is reported

  7. 建立健全的基础研究体制提升眼科创新能力%Platforms are needed for innovative basic research in ophthalmology

    Institute of Scientific and Technical Information of China (English)

    王宜强

    2012-01-01

    Basic research poses the cornerstone of technical innovation in all lines including medical sciences.Currently,there are shortages of professional scientists as well as technical supporting teams and facilities in the field of basic research of ophthalmology and visual science in China.Evaluation system and personnel policies are not supportive for innovative but high-risk-of-failure research projects.Discussion of reasons and possible solutions are given here to address these problems,aiming at promoting buildup of platforms hosting novel and important basic research in eye science in this country.%基础研究是技术创新的前提,医学领域同样如此.我国眼科领域正在努力加强基础研究领域建设,但目前在硬件(人员配备、仪器设备等)和软件(人才结构、技术支撑、科研文化等)方面均存在一些问题,主要表现为从事眼科基础研究的团队和提供支撑的技术团队力量薄弱、对基础研究活动和成果的评价体系不完善等.本文建议加强适合眼科创新性基础研究的人才队伍建设和科研体制建设.

  8. 眼科术后感染患者病原菌分布及其药敏性分析%Analysis on pathogen distribution and drug sensitivity in ophthalmological patients with postoperative infection

    Institute of Scientific and Technical Information of China (English)

    缪羽; 卢琤; 郭佳馨

    2016-01-01

    目的:研究眼科术后感染患者病原菌的分布情况,并分析其对各抗菌药物的药敏性,为临床及时、合理使用抗菌药物提供医学依据。方法选取2010年2月至2014年12月就诊于本院眼科的术后感染患者60例,通过涂片获得患者眼部病原菌,经革兰染色和药敏试验,针对病原菌的分布进行分析。结果检出的病原菌为革兰阴性菌、革兰阳性菌和真菌。有50.00%患者被检出革兰阳性菌,其中表皮葡萄球菌占21.67%;25.00%的患者被检出革兰阴性菌,其中铜绿假单胞菌占10.00%;有25.00%的患者被检出真菌。对病原菌进行药敏试验,革兰阴性菌中铜绿假单胞菌对阿米卡星、舒巴坦钠、他唑巴坦、亚胺培南、美罗培南的敏感性均大于或等于83.30%;革兰阳性菌中表皮葡萄球菌和金黄色葡萄球菌对利奈唑安、万古霉素和环丙沙星的敏感性均大于或等于75.00%。结论眼科术后患者感染的病原菌,革兰阴性菌、革兰阳性菌和真菌均有,对常用青霉素等有较高的耐药性,但不同的病原菌都有各自敏感性较高的药物,临床上有针对性地、及时地选择有效的抗菌药物进行预防或治疗,从而降低眼科术后的感染率。%Objective To investigate the pathogens distribution in the ophthalmological patients with postoperative infection and to analyze their sensitivity to various antibacterial drugs in order to provide the medical evidence for rational and timely use of anti‐bacterial drugs in clinic .Methods Sixty cases postoperative infection in the ophthalmological department of our hospital from Feb‐ruary 2010 to December 2014 were selected .The pathogens in the ocular region were obtained by smear and performed the Gram staining and drug susceptibility test .The pathogens distribution was analyzed .Results The detected pathogens were Gram‐negative bacteria ,Gram

  9. Crosslinking: methodological approaches and application in ophthalmology

    Directory of Open Access Journals (Sweden)

    I. B. Medvedev

    2016-01-01

    Full Text Available Crosslinking of the cornea was developed at the end of the last century and radically changed approaches to the treatment of progressive corneal ectasia. To achieve the strengthening of the corneal tissue irradiation with ultraviolet light And is combined with the use of Riboflavin. Riboflavin plays a role of a photosensitizer in the process of photopolymerization and ultraviolet irradiation increases the formation of inter — and intrafibrillary covalent bonds. Standard Protocol operation involves the scarification of epithelium, a 30‑minute application of 0.1 % solution of Riboflavin with subsequent 30 min. irradiation with ultraviolet light with A wavelength of 370 nm and 3 mW / cm2. The lack of effect of routine procedures is defined as the increase in refractive power of the cornea by 1 Diopter. after treatment and observed in 8.1‑33.3 % of cases. A relatively frequent complication of the standard procedure of crosslinking (10‑90 % is corneal haze. A number of cases of infectious keratitis, including bacterial, protozoan and fungal forms is registered. Rare complications after standard procedure of crosslinking are diffuse lamellar keratitis, melting corneal and endothelial-epithelial dystrophy. After instillation of Riboflavin its diffusion in the corneal stroma is limited by a dense contacts between epithelial cells, resulting in crosslinking often resort to preliminary scarification of epithelium. However, this manipulation is the cause of the complications of crosslinking, as intra — and postoperative pain, infectious keratitis and lethargic regeneration of the epithelium. The permeability of the epithelium for Riboflavin can be enhanced in several ways, for example, modifying physico-chemical properties of Riboflavin molecules or increasing the permeability of the epithelium, for example, by instillation of a 40 % strength solution of glucose. It was shown that the conducting electrophoresis with Riboflavin for 5 minutes, allows to reach a concentration in the cornea sufficient to conduct the crosslinking. There have also been attempts to reduce the time of the operation of crosslinking by increasing the power of irradiation of cornea with ultraviolet light. In single studies reported on the successful use of corneal crosslinking combined with photorefractive keratectomy and intracorneal the rings, as well as for the treatment of infectious keratitis and endothelial-epithelial dystrophy of the cornea.

  10. The gene therapy revolution in ophthalmology

    Science.gov (United States)

    Al-Saikhan, Fahad I.

    2013-01-01

    The advances in gene therapy hold significant promise for the treatment of ophthalmic conditions. Several studies using animal models have been published. Animal models on retinitis pigmentosa, Leber’s Congenital Amaurosis (LCA), and Stargardt disease have involved the use of adeno-associated virus (AAV) to deliver functional genes into mice and canines. Mice models have been used to show that a mutation in cGMP phosphodiesterase that results in retinitis pigmentosa can be corrected using rAAV vectors. Additionally, rAAV vectors have been successfully used to deliver ribozyme into mice with a subsequent improvement in autosomal dominant retinitis pigmentosa. By using dog models, researchers have made progress in studying X-linked retinitis pigmentosa which results from a RPGR gene mutation. Mouse and canine models have also been used in the study of LCA. The widely studied form of LCA is LCA2, resulting from a mutation in the gene RPE65. Mice and canines that were injected with normal copies of RPE65 gene showed signs such as improved retinal pigment epithelium transduction, visual acuity, and functional recovery. Studies on Stargardt disease have shown that mutations in the ABCA4 gene can be corrected with AAV vectors, or nanoparticles. Gene therapy for the treatment of red–green color blindness was successful in squirrel monkeys. Plans are at an advanced stage to begin clinical trials. Researchers have also proved that CD59 can be used with AMD. Gene therapy is also able to treat primary open angle glaucoma (POAG) in animal models, and studies show it is economically viable. PMID:24227970

  11. JOURNAL ANALYSIS ON OPHTHALMOLOGY AND OTHERS

    Directory of Open Access Journals (Sweden)

    Denise de Freitas

    Full Text Available Objective: To update knowledge and methods to access and view the journals included in Qualis of CAPES Medicine III, and how to measure the impact factor. Method: Document review on the attempt to verify the way Qualis uses for ranking journals cited by the post-graduate programs of Medicine III in their evaluation periods, and the impact factors obtained by journals indexing base. Results: The classification is annual and are ranking in strata ranging from A1, the highest, and A2; B1; B2; B3; B4; B5; C. The latter has zero evaluation weight. These strata take as reference the impact factor of the journals listed by the programs. The same journal can be classified into different Qualis in other areas, and this is no inconsistency, but expressed the assigned value, in each area, at that particular journal. The Impact Factor is measured using the Journal of Citation Report in Web of Knowledge website. Conclusion: Using the criteria established by WebQualis for stratification of journals there is a quality guidance of what is produced by the program and, based on it, can be made scientific comparison of program performance. Consulting the JCR is recommended because it defines exactly what is the journal's impact factor; Qualis stratifies numerical intervals and not individual journal specificity.

  12. Amiodarone Pulmonary, Neuromuscular and Ophthalmologic Toxicity

    Directory of Open Access Journals (Sweden)

    Karen EA Burns

    2000-01-01

    Full Text Available Amiodarone is an iodinated benzofuran derivative class III antiarrhythmic that is highly effective in suppressing ventricular and supraventricular arrhythmias. It is also associated with an imposing side effect profile, which often limits its use. Numerous adverse effects have been documented including skin discolouration, photosensitivity, hepatitis, thyroid dysfunction, corneal deposits, pulmonary fibrosis, bone marrow suppression and drug interactions. These side effects are thought to be correlated with the total cumulative dose of amiodarone, but idiopathic reactions have been reported. The majority of adverse reactions resolve with discontinuation of the drug; however, rapid progression may occur, which may be fatal. The present report documents a patient who had a combination of serious amiodarone toxicities that, once recognized, were treated and eventually resulted in a good outcome.

  13. A Review of Neuro-ophthalmologic Emergencies

    African Journals Online (AJOL)

    Alasia Datonye

    Visual loss is believed to result from interruption of mitrochondrial ... Most patients present acutely with pain around the eye ... mass effect on adjacent structures such as the optic chiasm ... attention to cerebrospinal fluid opening pressure is.

  14. Visual fields in neuro-ophthalmology.

    Science.gov (United States)

    Kedar, Sachin; Ghate, Deepta; Corbett, James J

    2011-01-01

    Visual field assessment is important in the evaluation of lesions involving the visual pathways and should be performed at baseline and periodically in the follow-up. Standard automated perimetry has been shown to be adequate in neuro-ophthalmic practise and is now the technique of choice for a majority of practitioners. Goldman kinetic visual fields are useful for patients with severe visual and neurologic deficits and patients with peripheral visual field defects. Visual fields are useful in monitoring progression or recurrence of disease and guide treatment for conditions such as idiopathic intracranial hypertension (IIH), optic neuropathy from multiple sclerosis, pituitary adenomas, and other sellar lesions. They are used as screening tools for toxic optic neuropathy from medications such as ethambutol and vigabatrin. Visual field defects can adversely affect activities of daily living such as personal hygiene, reading, and driving and should be taken into consideration when planning rehabilitation strategies. Visual field testing must be performed in all patients with lesions of the visual pathway.

  15. [Comparative ophthalmology in the Middle Ages].

    Science.gov (United States)

    Norn, M; Norn, O

    2001-01-01

    Descriptions of animal eyes in the Middle Ages in the learned work Physiologus from the 4th century, based on Aristoteles, Plutarc, the Bible etc. are commented on. The modern biologist is horrified, the historian understands the ethical - religious aspects behind the edifying stories concerning the lion, gazelle, eagle, snake, lizard, swallow etc. Medical science and theology were not separated in the Middle Ages.

  16. [Technical principles of adaptive optics in ophthalmology].

    Science.gov (United States)

    Reiniger, J L; Domdei, N; Holz, F G; Harmening, W M

    2017-02-13

    During the last 25 years ophthalmic imaging has undergone a revolution. This review gives an overview of the possibilities of adaptive optics (AO) for ophthalmic imaging technologies and their development and illustrates that the role of ophthalmic imaging changed from the documentation of obvious abnormalities to the detection of microscopic yet significant conspicuities. This enables earlier and more precise diagnoses. The implementation of AO for imaging systems like fundus cameras, scanning laser ophthalmoscopy and optical coherence tomography has gained in importance. In recent years a couple of companies started developing commercially available AO systems, thus, indicating a future use in clinical routine.

  17. The use of botulinum toxin in ophthalmology.

    Science.gov (United States)

    Denniston, A; Reuser, T

    2001-08-01

    As the diversity of clinical applications for the botulinum neurotoxin continues to grow, exciting developments are occurring in its use around the eye, where indeed its benefits were first recognized. These include use to treat strabismus, eyelid disorders and a number of other ocular conditions.

  18. JOURNAL ANALYSIS ON OPHTHALMOLOGY AND OTHERS.

    Science.gov (United States)

    Freitas, Denise de

    2015-01-01

    To update knowledge and methods to access and view the journals included in Qualis of CAPES Medicine III, and how to measure the impact factor. Document review on the attempt to verify the way Qualis uses for ranking journals cited by the post-graduate programs of Medicine III in their evaluation periods, and the impact factors obtained by journals indexing base. The classification is annual and are ranking in strata ranging from A1, the highest, and A2; B1; B2; B3; B4; B5; C. The latter has zero evaluation weight. These strata take as reference the impact factor of the journals listed by the programs. The same journal can be classified into different Qualis in other areas, and this is no inconsistency, but expressed the assigned value, in each area, at that particular journal. The Impact Factor is measured using the Journal of Citation Report in Web of Knowledge website. Using the criteria established by WebQualis for stratification of journals there is a quality guidance of what is produced by the program and, based on it, can be made scientific comparison of program performance. Consulting the JCR is recommended because it defines exactly what is the journal's impact factor; Qualis stratifies numerical intervals and not individual journal specificity. Atualização do conhecimento dos meios e métodos de acessar e visualizar os periódicos do Qualis da Medicina III da CAPES e a mensuração do Fator de Impacto. Buscou-se verificar a forma utilizada pelo Qualis para classificar os periódicos referidos pelos programas de pós-graduação da Medicina III em seus períodos de avaliação e os fatores de impacto obtidos pelas revistas em base indexadora. A classificação é anual e são enquadrados em estratos que variam de A1, o mais elevado, a A2; B1; B2; B3; B4; B5; C. Este último tem peso zero. Esses estratos levam como referência o Fator de Impacto dos periódicos referidos pelos programas. Um mesmo periódico pode ter classificação em Qualis diferentes em outras áreas, e isto não constitui inconsistência, mas expressa o valor atribuído, em cada área, àquela determinada revista científica. O Fator de Impacto é mensurado navegando-se no site do Journal of Citation Report da Web of Knowledge. A utilização dos critérios estabelecidos pelo WebQualis para estratificação dos periódicos é norteadora da qualidade do que se produz nos programas e, com base nela, pode-se fazer comparações de desempenho científico. Já a consulta ao JCR é complementarmente adequada de ser feita porque define com exatidão qual é o fator de impacto da revista, em função de que o Qualis estratifica faixas numéricas e não especificidade individual do periódico.

  19. Department of Ophthalmology, College of Health Sciences ...

    African Journals Online (AJOL)

    2007-03-01

    Mar 1, 2007 ... INTRODUCTION dusty climates. In May 1998, the .... of TF = 15%, precision + 5% and design effect. = 4. 3. .... Trachoma is "one of the forgotten focal tropical infectious ... Concrete water jars have been replaced with plastic.

  20. Stem Cell Ophthalmology Treatment Study II

    Science.gov (United States)

    2017-01-03

    Retinal Disease; Age-Related Macular Degeneration; Retinitis Pigmentosa; Stargardt Disease; Optic Neuropathy; Nonarteritic Ischemic Optic Neuropathy; Optic Atrophy; Optic Nerve Disease; Glaucoma; Leber Hereditary Optic Neuropathy

  1. The gene therapy revolution in ophthalmology.

    Science.gov (United States)

    Al-Saikhan, Fahad I

    2013-04-01

    The advances in gene therapy hold significant promise for the treatment of ophthalmic conditions. Several studies using animal models have been published. Animal models on retinitis pigmentosa, Leber's Congenital Amaurosis (LCA), and Stargardt disease have involved the use of adeno-associated virus (AAV) to deliver functional genes into mice and canines. Mice models have been used to show that a mutation in cGMP phosphodiesterase that results in retinitis pigmentosa can be corrected using rAAV vectors. Additionally, rAAV vectors have been successfully used to deliver ribozyme into mice with a subsequent improvement in autosomal dominant retinitis pigmentosa. By using dog models, researchers have made progress in studying X-linked retinitis pigmentosa which results from a RPGR gene mutation. Mouse and canine models have also been used in the study of LCA. The widely studied form of LCA is LCA2, resulting from a mutation in the gene RPE65. Mice and canines that were injected with normal copies of RPE65 gene showed signs such as improved retinal pigment epithelium transduction, visual acuity, and functional recovery. Studies on Stargardt disease have shown that mutations in the ABCA4 gene can be corrected with AAV vectors, or nanoparticles. Gene therapy for the treatment of red-green color blindness was successful in squirrel monkeys. Plans are at an advanced stage to begin clinical trials. Researchers have also proved that CD59 can be used with AMD. Gene therapy is also able to treat primary open angle glaucoma (POAG) in animal models, and studies show it is economically viable.

  2. [Morphological basics of scientific research in ophthalmology].

    Science.gov (United States)

    Fedorov, A A

    2013-01-01

    The article summarizes the results of a complex study on lacrimal gland secretion (crystallography), meibomian gland secretion (evaluation of the lipid layer in the intermarginal space of the eyelids) and nasolacrimal contents in dacryostenosis (cytology), and ocular surface condition in conjunctival pathology (impressional cytology). Samples of subretinal tissue (removed during endoscopic surgery in patients with age-related macular degeneration) and corneas (obtained in penetrating mini-keratoplasty performed after previous photorefractive or phototherapeutic keratoplasty) were studied by means of light and electronic microscopy. Engraftment potential of different implants used in orbital plastic surgery was studied experimentally. Data on prenatal development of retinal vascular system and structures responsible for proper ocular hydrodynamics is provided.

  3. [Equipment for spray-freezing in ophthalmology].

    Science.gov (United States)

    Anders, M; Matthes, R

    1991-05-01

    The authors discuss the theoretical background of the method of spray/freezing for destructive processes and their advantages. They demonstrate a cryo-apparatus IKG 3 for liquid nitrogen which is part of the Dresden equipment and was elaborated by the department for cryomedicine of the "Carl Gustav Carus" Academy in cooperation with the Technical University in Dresden. The apparatus produces a fine dispensable spray of the cooling mixture and permits treatment even of small tissue areas.

  4. Visual fields in neuro-ophthalmology

    Directory of Open Access Journals (Sweden)

    Kedar Sachin

    2011-01-01

    Full Text Available Visual field assessment is important in the evaluation of lesions involving the visual pathways and should be performed at baseline and periodically in the follow-up. Standard automated perimetry has been shown to be adequate in neuro-ophthalmic practise and is now the technique of choice for a majority of practitioners. Goldman kinetic visual fields are useful for patients with severe visual and neurologic deficits and patients with peripheral visual field defects. Visual fields are useful in monitoring progression or recurrence of disease and guide treatment for conditions such as idiopathic intracranial hypertension (IIH, optic neuropathy from multiple sclerosis, pituitary adenomas, and other sellar lesions. They are used as screening tools for toxic optic neuropathy from medications such as ethambutol and vigabatrin. Visual field defects can adversely affect activities of daily living such as personal hygiene, reading, and driving and should be taken into consideration when planning rehabilitation strategies. Visual field testing must be performed in all patients with lesions of the visual pathway.

  5. Bibliometric trends in ophthalmology 1997-2009

    Directory of Open Access Journals (Sweden)

    Ahmad M Mansour

    2015-01-01

    Full Text Available Aims: To track citation patterns in ophthalmic journals and contrast them with major medical and surgical journals from 1997 to 2009. In addition, we want to familiarize the ophthalmic community with bibliometrics indices. Materials and Methods: Data retrieved from Institute for Scientific Information and related websites include 2-year journal impact factor JIF, 5-year impact, Eigenfactor score, H-factor, Article Influence score, and SCImago factor. Results: JIF rose steadily around 10% annually in ophthalmic journals, and likewise for major medical and surgical journals. JIF correlated with recent bibliometric indicators like 5-year impact, H index, and SCImago factor but not with Eigenfactor. Ophthalmic journals publishing reviews, basic science, or large volume on broad range of topics ranked at the top for JIF, while subspecialty journals tended to have low JIF. JIF of subspecialty journal Retina rose from 0.740 (rank 23 in 2000 to 3.088 in 2007 (rank 6. Conclusions: JIF tends to rise annually by 10% in medical, surgical, and ophthalmic fields. Journals publishing reviews, basic science, or large volume on broad range of topics rank at the top for JIF. The rapid rise of JIF for Retina unlike other subspecialties that stayed status quo is multifactorial: Change in editorial policies (introduction of review articles and omission of case reports and technological advances in the retinal field.

  6. Bibliometric trends in ophthalmology 1997-2009

    OpenAIRE

    2015-01-01

    Aims: To track citation patterns in ophthalmic journals and contrast them with major medical and surgical journals from 1997 to 2009. In addition, we want to familiarize the ophthalmic community with bibliometrics indices. Materials and Methods: Data retrieved from Institute for Scientific Information and related websites include 2-year journal impact factor JIF, 5-year impact, Eigenfactor score, H-factor, Article Influence score, and SCImago factor. Results: JIF rose steadily around 10% annu...

  7. [Contemporary potential of nonmedical treatment in ophthalmology].

    Science.gov (United States)

    Drakon, A K; Elfimov, M A; Illarionov, V E; Ivanova, I I; Portnov, V V

    2016-01-01

    The article covers treatment results of 90 patients with primary glaucoma simplex of stage 1 and 2 (137 eyes). The authors proved that using a specified magnetotherapy method, when compared to regular medical therapy, causes more fast and marked regression in clinical symptoms and improvement of vision in patients with primary glaucoma simplex of stages 1 and 2.

  8. American Association for Pediatric Ophthalmology and Strabismus

    Science.gov (United States)

    ... Corneal Abrasions Dilating Eye Drops Lazy eye (defined) Pink eye (defined) Retinopathy of Prematurity Strabismus Stye (defined) Vision ... Corneal Abrasions Dilating Eye Drops Lazy eye (defined) Pink eye (defined) Retinopathy of Prematurity Strabismus Stye (defined) Vision ...

  9. Gamma radiation sterilized amnion: use in ophthalmology

    Energy Technology Data Exchange (ETDEWEB)

    Martinez P, M. E. [ININ, Carretera Mexico-Toluca s/n, Ocoyoacac 52750, Estado de Mexico (Mexico); Leon T, Y. [Hospital General Regional 220, IMSS, Paseo Tollocan No. 620, Col. Vertice, Toluca 50150, Estado de Mexico (Mexico); Vazquez M, L., E-mail: esther.martinez@inin.gob.m [Hospital General de Mexico, Dr. Balmis 148, Col. Doctores, 06720 Mexico D. F. (Mexico)

    2010-10-15

    Amnion processed at the Radio sterilized Tissue Bank at the National Institute of Nuclear Research, sterilized with {sup 60}Co gamma radiation, have been used in Mexico since 2005 either as a graft to replace the damaged ocular surface, or as a patch to prevent unwanted inflammatory reactions. Patients from the Hospital General de Mexico (HGM) and Instituto Mexicano del Seguro Social (IMSS), suffering diverse pathologies such as keratoconjunctivitis; recurrent pterygium associated with symblepharon; corneal neuro trophic ulcers, chemical and thermal burns, and corneal thinning s, had been successfully treated with irradiated amnion. In the HGM, a clinical prospective study on lesions of the ocular surface of 17 eyes from 15 patients, affected with the above mentioned pathologies, was successful in 88.2%. The results have proven to be excellent as much for cosmetic purposes as for functional ones. Without the treatment, the patients could have suffered a healing after-effect or loss of sight. At IMSS, a controlled clinical randomized trial with 108 eyes from 100 patients, affected with primary nasal pterygium, was performed in 2009. These eyes were treated with radio sterilized amnion and intraoperative mitomycin C to prevent recurrence after excision of the primary pterygium. The preliminary results do not shown adverse reaction, inflammation and pain were significantly reduced radio sterilized amnion also offer security because they do no express antigens HLA-A, B or Dr and the sterile irradiated tissue do not provoke rejection or transmit an infective disease. (Author)

  10. Radionuclide methods of tumor diagnosis in ophthalmology

    Energy Technology Data Exchange (ETDEWEB)

    Dubinskaya, L.R. (Nauchno-Issledovatel' skij Inst. Glaznykh boleznej (USSR))

    1982-08-01

    The radionuclide methods used in opthalmology for diagnosis of eyes and orbit tumors are described: radiophosphorus indication, method of gamma-topography, method of external radiometry, method of blood circulation study in organ of vision. Diagnostic value was determined of such radiopharmaceuticals as /sup 32/P-phosphate, /sup 67/Ga-citrate, /sup 131/I-Ralbumin, /sup 197/Hg-neohydrine, /sup 125/I-fluorescein, /sup 75/Se-methionine, sup(99m)Tc-pertechnete and others. The conclusion was drawn that the considered radionuclides and radiopharmaceuticals were not perfect indicators for diagnosis of different tumors of organ of vision. Simultaneous using of several radiopharmaceuticals with the aim of increasing information content of described methods is recommended.

  11. Resultados del LASIK miópico en el Instituto Cubano de Oftalmología "Ramón Pando Ferrer" Results of myopic LASIK obtained at “Ramón Pando Ferrer” Cuban Institute of Ophthalmology

    Directory of Open Access Journals (Sweden)

    Isabel Cristina Lantigua Maldonado

    2012-06-01

    Full Text Available Objetivos: Evaluar los resultados y la estabilidad del LASIK miópico realizado en el Instituto Cubano de Oftalmología "Ramón Pando Ferrer". Métodos: Se realizó un estudio descriptivo, prospectivo y comparativo. El universo estuvo compuesto por los pacientes operados mediante LASIK (4 011 ojos desde el inicio en nuestro centro (2005 de la cirugía refractiva corneal con láser de excímeros. Se seleccionaron los pacientes con estudios realizados un año después de la cirugía. Las variables estudiadas fueron queratometría, mejor agudeza visual sin corrección, mejor agudeza visual con corrección, equivalente esférico, paquimetría y topografía. Se compararon las variables antes de la cirugía y al año de esta. Los resultados se analizaron mediante la prueba t de Student para datos pareados con significación estadística cuando pObjective: To evaluate the results and the stability of the myopic Lasik carried out in “Ramón Pando Ferrer” Cuban Institute of Ophthalmology. Methods: A prospective, descriptive and comparative study was conducted. The universe of study was made up of the patients operated on by LASIK (4011 eyes from the beginning of the corneal refractive surgery with excimer laser in our center in 2005. The patients were selected from those that had been studied for ametropy correction one year after the surgery. The studied variables were keratometry, better visual acuity without correction, better visual acuity with correction, spherical equivalent, pachymetry and topography, and the obtained results were compared before and at one year of the surgery. The paired T test served to analyze the results with statistical significance of p < 0.05. Results: Significant changes took place in keratometry and spherical equivalent that brought about improved visual acuity without correction for distance vision. The best visual acuity with correction remained the same before and after the surgery. Pachymetry remained within safe

  12. 喉罩联合无肌松全麻在小儿眼科手术中的应用%The application of LMA combined with general anesthesia without muscle relaxants in the pediatric department of ophthalmology operation

    Institute of Scientific and Technical Information of China (English)

    贺伟忠; 杨义; 范小丽; 李萌

    2014-01-01

    目的:研究无肌松全麻联合喉罩置入对小儿眼科手术围术期应激反应的影响。方法选择全身麻醉下小儿眼科手术患者90例,随机分为A、B两组,每组各45例。 A组使用肌松药插入气管导管,B组采用无肌松药全麻并置入喉罩。对比手术中各时间点的平均动脉压(MAP)、心率(P)、心率收缩压乘积(RPP)、血氧饱和度(SpO2)。观察两组拔管期呛咳、躁动等拔管反应,并记录拔管(喉罩)时间、麻醉药总量。结果A组麻醉诱导及拔管期血流动力学波动高于B组;A组严重呛咳、躁动例数高于B组;A组拔管时间长于B组;A组麻醉药物总量多于B组。结论喉罩联合无肌松全麻应用于小儿眼科手术安全可靠,相较气管插管围术期应激反应更低。%Objective To study without muscle relaxants combined general effect of laryngeal mask insertion on the pe-diatric department of ophthalmology operation perioperative stress responses. Methods Ninety patients with pediatric eye surgery were randomly divided into group A and group B, 45 cases in each group. Group A treated with muscle re-laxants insert the tracheal tube, group B treated with without anesthesia and muscle relaxants into the LMA. Contrast surgery mean arterial pressure at each time point (MAP), heart rate (P), rate pressure product (RPP), oxygen saturation (SpO2). Extubation were observed choking, restlessness, etc. extubation reaction, record extubation (LMA) time, total quantity of using drug. Results A induction of anesthesia and extubation hemodynamic fluctuations was higher than that of group B; Severe cough, agitation of group A were higher than that in B group; The extubation time was longer than that of group B; Drug amount was higher than that of group B. Conclusion LMA Joint no muscle relaxant used in pe-diatric anesthesia eye surgery is safe and reliable, with lower stress response.

  13. Perfil oftalmológico dos alunos do programa alfabetização solidária em quatro municípios do Ceará Ophthalmological profile of adult students belonging to a literacy program in four cities of Ceará

    Directory of Open Access Journals (Sweden)

    Islane Castro Verçosa

    2003-01-01

    Full Text Available OBJETIVO: Avaliar o perfil oftalmológico de estudantes da Alfabetização Solidária no Estado do Ceará, identificar as principais causas de baixa acuidade visual, descrever a experiência e os principais resultados obtidos. MÉTODOS: Foram utilizados para o exame oftalmológico de mil e sete (1007 alunos do Programa Alfabetização Solidária dois refratores automatizados, dois refratores tipo Greens, duas colunas pantográficas, duas cadeiras, quatro oftalmoscópios, uma lâmpada de fenda portátil, dois tonômetros de aplanação, um oftalmoscópio indireto. Participantes: alfabetizadores treinados para medida da acuidade visual, oftalmologistas, residentes de oftalmologia, auxiliares e secretárias. RESULTADOS: Observamos que cerca da metade dos alunos (46% tinha baixa de acuidade visual (acuidade visual menor que 0,8 em ambos os olhos, 66,33% da população estudada necessitou correção óptica, destes, 37,00% eram présbitas. Predominou a população na faixa de 41 a 50 anos. A maioria da população examinada era do sexo feminino (56%. Trinta e nove por cento da po- pulação estudada apresentou alguma doença oftalmológica. Encontramos o pterígio e a catarata como doenças mais freqüentes. CONCLUSÃO: O programa deve ter no início do seu funcionamento prévio exame oftalmológico dos alunos de cada comunidade, para melhor aproveitamento do conteúdo ensinado, diminuindo desta forma a grande evasão escolar.PURPOSE: To evaluate the ophthalmologic profile of "Alfabetização Solidária" - a program that teaches illiterate adults how to read and write; to identify the main causes of low visual acuity; to show our experience and the main results of promoting visual health in the community. METHODS: Ophthalmologic equipment (two automatic refractors, two Green refractors, two supports, two chairs, four ophthalmoscopes, one portable slit lamp, two applanation tonometers, one indirect ophthalmoscope. PARTICIPANTS: Teachers trained to

  14. Estudo do impacto de um curso MBA Gestão em Saúde na modernidade organizacional de clínicas oftalmológicas Study of the impact of a MBA Administration in Health course on the organizational modernity of ophthalmologic clinics

    Directory of Open Access Journals (Sweden)

    Manuel Meireles

    2005-12-01

    Full Text Available OBJETIVO: Pesquisa no campo da aprendizagem de competências que busca investigar o impacto da aquisição de novas competências individuais dos responsáveis de clínicas oftalmológicas, por meio de um curso MBA Gestão em Saúde, na modernidade organizacional de clínicas oftalmológicas. MÉTODOS: Levantamento utilizando questionários aplicados a alunos e ex-alunos do curso e a gestores de clínicas oftalmológicas não vinculados ao curso (n=30 cada um. A análise foi feita por meio de métodos estatísticos: r de Pearson e Q de Yule; testes t de Student, da soma de séries, da mediana e teste U de Mann-Whitney. RESULTADOS: Observou-se correlação linear e positiva entre a excelência do MBA Gestão em Saúde e o desenvolvimento de capacidades dos alunos veteranos (correlação rho de Spearman em nível de 0,01; há diferença significativa (0,0364, pelo teste de Mann-Whitney, entre alunos veteranos e alunos calouros, quanto à necessidade de se ampliar as capacidades individuais que o curso MBA Gestão em Saúde fornece, aos demais funcionários operacionais das clínica oftalmológicas; e há diferença significativa (0,0057, pelo teste de Mann-Whitney, entre alunos veteranos do curso MBA Gestão em Saúde e alunos calouros quanto à importância da modernidade organizacional para as clínicas oftalmológicas. CONCLUSÕES: Os resultados obtidos são consistentes, de forma geral, com o modelo proposto: a excelência do MBA Gestão em Saúde contribui significativamente para a modernidade organizacional, para o desenvolvimento de competências dos alunos egressos e ainda de forma substancial para a percepção de hiatos organizacionais.PURPOSE: Investigations in the field of the learning competence that investigate the impact of the acquisition of new individual competence of those responsible for ophthalmologic clinics, by means of a MBA Administration in Health course, on the organizational modernity of ophthalmologic clinics. METHODS

  15. Application of problem based learning steered by constructivism in Ophthalmologic teaching%建构主义理论指导下的以问题为基础的学习在眼科教学中的应用

    Institute of Scientific and Technical Information of China (English)

    王欣玲; 秦宇; 孙晓红; 张劲松; 阎启昌

    2014-01-01

    AIM: To investigate the application of problem based learning ( PBL) steered by constructivism. METHODS: The 120 students were appointed as the routine teaching group and the PBL steered by constructivism group separately, who were coming from the department of clinical medicine and clinical pharmacy in grade 94 , China Medical University. They were divided into PBL steered by constructivism group ( 60 students) and the routine teaching group (60 students). The students' feedbacks and teaching effects were compared by the questionnaire after teaching. RESULTS: The feedback of the students in the PBL steered by constructivism group were significant better than that in the routine teaching group, including interest, referring data, self-study, thought process, obtaining and spreading knowledge, computer utilization, studying independently, concerted struggling, appreciating and magnanimous ability, discussion and communication (P CONCLUSION: Application of problem based learning steered by constructivism interests the students in Ophthalmologic teaching and is helpful in their self-study, which is benefit to elevate the teaching level and train the qualified scientists.%目的:探讨建构主义理论指导下的以问题为基础的学习( problem based learning, PBL )教学法在眼科教学中的应用。  方法:以中国医科大学94期临床医学和临床药学专业学生120人为研究对象,在眼科教学过程中分为建构主义理论指导下的 PBL 教学组(60人)和常规教学组(60人)。在教学结束后进行问卷调查,比较两组的教学效果和学生的反馈。  结果:建构主义理论指导下的PBL教学组学生在对眼科学教学内容感兴趣、愿意主动查阅相关书籍文献、提高自学能力和自己分析解决问题的能力、发展高层次的思维能力、提高获取和评价信息的能力、提高传播信息的技能、提高计算机运用能力、将理论知识与临

  16. 1273例Ⅰ类切口眼科手术预防性应用抗菌药物合理性分析%Rationality of the Preventive Use of Antibiotics in Ophthalmologic Patients with Type Ⅰ Incision: Analysis of 1 273 Cases

    Institute of Scientific and Technical Information of China (English)

    邢颖; 梁健华; 甄健存

    2009-01-01

    目的:分析我国Ⅰ类切口眼科手术预防性应用抗菌药物合理性.方法:采用病例回顾的方法,随机抽取卫生部全国抗菌药物临床应用监测网收集的2006~2007年全国113家医院Ⅰ类切口眼科手术预防性应用抗菌药物1 273例,分析不同给药途径的合理性.结果:局部用药(滴眼和局部注射)应用基本合理,但是全身用药(静脉注射和口服)的药物选择级别过高、抗菌谱不合适、用药时机过晚.结论:眼科手术预防性应用抗菌药物应重视术前局部用药,同时注重剂型的合理应用.%To analyze the rationality of the preventive use of antibiotics in Chinese ophthalmologic patients with type Ⅰ incision. METHODS: By means of retrospective study, a total of 1 273 ophthalmologic cases from 113 hospitals of 2006~2007 from National Monitoring Network of Ministry of Health for Clinical Application of Antibiotic with type Ⅰ incision involving preventive administration of antibiotics via different routes were analyzed. RESULTS: The local administration (eye drops and local injection) was rational on the whole, but the systemic administration (intravenous or oral administration) was irrational to some degree in which the drug grade was on the high side, the antibacterial spectrum was inappropriate, and the medication time was delayed. CONCLUSION: Preoperative local administration and rational use of dosage forms should be emphasized in the preventive use of antibiotics for patients undergoing ophthalmologic surgery.

  17. Clinical Analysis of Pranoprofen Combined With Sodium Hyaluronate in the Treatment of Dry Eye Syndrome After Operation by Department of Ophthalmology%眼科手术后干眼症采用普拉洛芬联合玻璃酸钠治疗的临床分析

    Institute of Scientific and Technical Information of China (English)

    张丹

    2015-01-01

    Objective To explore the clinical effect of dry eye syndrome after department of ophthalmology operation using pranoprofen combined with sodium hyaluronate in the treatment. Methods This medical research methods between 2012 January to 2014 January in our hospital treated 100 cases of dry eye patients in department of ophthalmology after operation to observe the object,randomly divided into the control group and the experimental group,the control group received sodium hyaluronate treatment,the experimental group received pranoprofen combined glass acid sodium treatment,compared two groups of patients. Results The experimental group for the BUT value in the clinical treatment and Schirmer test results of observation indexes were significantly better than the control group (P<0.05). Conclusion Pranoprofen combined with sodium hyaluronate in the treatment of dry eye patients in department of ophthalmology after surgery,with the ideal effect.%目的:探讨眼科手术后干眼症采用普拉洛芬联合玻璃酸钠治疗的临床效果。方法本次医学研究选取2012年1月~2014年1月之间在我院接受治疗的100例眼科手术后干眼症患者为观察对象,随机将其分为对照组和实验组,对照组接受玻璃酸钠治疗,实验组接受普拉洛芬联合玻璃酸钠治疗,对比两组患者疗效。结果实验组换在临床治疗后BUT值和Schirmer试验结果等观察指标均明显优于对照组(P<0.05)。结论眼科手术后干眼症患者接受普拉洛芬联合玻璃酸钠治疗,具有较为理想的效果。

  18. The influence of psychological nursing in preoperative interview on physiological and psychological stress response of patients with local anaesthesia in the department of ophthalmology%术前访视心理护理对眼科局麻患者心理、生理应激的影响

    Institute of Scientific and Technical Information of China (English)

    侯华丽

    2012-01-01

    Objective To study the application effect of psychological nursing in preoperative interview in department of ophthalmology patients with local anesthesia.Methods Eighty patients with local anesthesia in department of ophthalmology were divided into the observation group and the control group with 40 cases in each group,the control group was given routine nursing,the observation group was strengthen psychological nursing care in preoperative interview,two groups were compared with psychological,physiological stress response.Results Anxiety,depression score,heart rate,blood pressure,norepinephrine (NE),epinephrine (E) concentrations 30 min before the operation in the observation group were significantly lower than those in control group (P < 0.05).Conclusions Psychological nursing in preoperative interview can relieve psychological,physiological stress response of local anesthesia operation patients in department of ophthalmology.It is conducive to the rehabilitation of postoperative patients.%目的 探讨术前访视心理护理在眼科局部麻醉患者中的应用.方法 将80例眼科局部麻醉手术患者分为观察组和对照组各40例,对照组采用常规护理,观察组在对照组的基础上于术前访视中加强心理护理,比较两组患者心理、生理应激反应.结果 观察组术前30 min的焦虑、抑郁评分及心率、血压、NE、E浓度均显著低于对照组(P<0.05).结论 术前访视心理护理能够减轻眼科局麻手术患者心理、生理应激反应,有利于患者术后康复.

  19. Qualidade do serviço oftalmológico prestado aos pacientes ambulatoriais do Sistema Único de Saúde - SUS Ophthalmological service quality offered to outpatients of the Public Healthcare System

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    Benigno Vicente Santos Hercos

    2006-04-01

    and priority in order to improve its quality. METHODS: A quantitative descriptive study was carried out on 100 outpatients of the public healthcare system which were submitted to ophthalmic tests at Fundação Hilton Rocha - Belo Horizonte - MG, from July 1st - July 30th 2004. Individual interviews were carried out by giving the interviewees two structured questionnaires adapted from the modified SERVQUAL. This scale is in agreement with the reality of the studied institute. RESULTS: The adapted SERVQUAL scale was submitted to statistical validation and it showed a suitable internal consistency index. In general terms, a slight general dissatisfaction was detected regarding ophthalmological service quality. The interviewees cared more about safety and reliability. A higher degree of dissatisfaction was detected mainly concerning fulfillment of procedures at scheduled appointments related to the execution of services within due timelimits. CONCLUSIONS: The institute is supposed to plan as well as carry out actions which lead to a general improvement in the patient's satisfaction regarding service quality and mainly reliability. Service quality monitoring through periodic use of the SERVQUAL scale will not only make it possible to plan highly precise and effective intervention strategies in these and in other healthcare services but it will also allow monitoring the responses to these actions. All these actions will contribute to the improvement of the service in the system as a whole.

  20. Avaliação oftalmológica em pacientes submetidos a implante de drenagem em glaucomas refratários Ophthalmologic evaluation of patients submitted to drainage implant in refractory glaucoma

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    Natália Pimentel Moreno

    2009-04-01

    Full Text Available OBJETIVO: Avaliar aspectos pré e pós-operatórios em pacientes submetidos a implantes de drenagem. MÉTODOS: Foi realizado estudo retrospectivo, com pacientes submetidos a implante de drenagem no setor de glaucoma do Hospital Oftalmológico de Sorocaba no período de janeiro de 2004 a dezembro de 2006. No estudo foram avaliadas as seguintes características: sexo, idade, olho operado, tipo de glaucoma, número de cirurgias oculares anteriores, pressão intraocular prévia e após, conforme tempo de seguimento. Foram observadas a acuidade visual pré e pós-implante, o número de medicações antiglaucomatosas prescritas pós-implante, as principais complicações e reintervenções necessárias. RESULTADOS: Entre os 92 pacientes a proporção foi de 60 (65,3% do sexo masculino e 32 (34,7% do feminino. Os principais tipos de glaucoma foram: 38,9% (n=37 secundário a transplante de córnea e 25,3% (n=24 glaucoma neovascular. A média da pressão intraocular pré-implante foi de 32 (±11,29 mmHg e pós-implante foi de 18, (±8,16 mmHg em 95 (100% pacientes, 15,00 (±11,00 mmHg em 95 (100%, 16 (±11,64 mmHg em 54 (55,7% e 20 (±10,14 mmHg em 21 (21,6% para o período de 2 meses, 6 meses, 1 ano e 2 anos, respectivamente. As complicações mais frequentes foram extrusão do implante (8,5% e atalamia (5,4%. CONCLUSÃO: Observou-se evolução satisfatória nos pós-implantes, independente das diversas causas do glaucoma. Neste estudo foi encontrada redução significante da pressão intraocular 2 meses, 1 ano e 2 anos (pPURPOSE: To evaluate aspects of patients submitted to drainage implant procedures before and after surgery. METHODS: A retrospective study was done, with patients submitted to drainage implant procedures in the Glaucoma Sector of the Hospital Oftalmológico de Sorocaba, from January, 2004 to December, 2006. The following characteristics were evaluated: gender, age, treated eye, glaucoma type, number of previous ophthalmologic surgeries

  1. Neuro-Ophthalmological Disorders in Cerebral Palsy: Ophthalmological, Oculomotor, and Visual Aspects

    Science.gov (United States)

    Fazzi, Elisa; Signorini, Sabrina G.; La Piana, Roberta; Bertone, Chiara; Misefari, Walter; Galli, Jessica; Balottin, Umberto; Bianchi, Paolo Emilio

    2012-01-01

    Aim: Cerebral visual impairment (CVI) is a disorder caused by damage to the retrogeniculate visual pathways. Cerebral palsy (CP) and CVI share a common origin: 60 to 70% of children with CP also have CVI. We set out to describe visual dysfunction in children with CP. A further aim was to establish whether different types of CP are associated with…

  2. Neuro-Ophthalmological Disorders in Cerebral Palsy: Ophthalmological, Oculomotor, and Visual Aspects

    Science.gov (United States)

    Fazzi, Elisa; Signorini, Sabrina G.; La Piana, Roberta; Bertone, Chiara; Misefari, Walter; Galli, Jessica; Balottin, Umberto; Bianchi, Paolo Emilio

    2012-01-01

    Aim: Cerebral visual impairment (CVI) is a disorder caused by damage to the retrogeniculate visual pathways. Cerebral palsy (CP) and CVI share a common origin: 60 to 70% of children with CP also have CVI. We set out to describe visual dysfunction in children with CP. A further aim was to establish whether different types of CP are associated with…

  3. A clinical research of the cornea symmetry and refractive power of thyroid-associated ophthalmology disease%甲状腺相关眼病对角膜对称性及角膜屈光力的影响

    Institute of Scientific and Technical Information of China (English)

    余相均; 洪明胜; 余心洁; 陈捷灵; 张俐娜; 盛文; 毛剑波; 陈峰; 沈丽君

    2013-01-01

    目的 研究甲状腺相关眼病对角膜形态学及角膜屈光力的影响.方法 前瞻性病例对照研究.收集2012年12月至2013年5月在温州医科大学附属眼视光医院确诊为甲状腺相关眼病稳定期的患者24例(46眼)作为观察组,甲状腺相关眼病活动性的评估主要依据临床活动度评分CAS标准进行评估.收集与之年龄、性别相匹配的正常人30例(30眼)作为对照组.采用Pentacam测量2组角膜形态学参数及角膜屈光力,包括角膜表面变异指数(ISV)、垂直不对称指数(IVA)、高度不对称性指数(IHA)、高度离心指数(IHD)和最小曲率半径(Rim),角膜中央厚度(CCT),角膜前、后表面屈光力,角膜前、后表面散光度及散光轴向.应用眼球突出计(Hertel眼突计)测量观察组眼球突出度.用独立样本t检验或秩和检验对2组参数进行比较.结果 甲状腺相关眼病ISV中位数为21.0(10~71),高于正常组的14.0(10~34),Z=1.31,P<0.01;IVA为0.180(0.07~0.70),高于正常组的0.100 (0.50~0.37),Z=1.08,P<0.0I;IHA为5.95(0.0~28.7),高于正常组的1.65(0.2~13.9),Z=84.34,P<0.01;IHD为0.020±0.015,高于正常组的(0.010±.0040),t=5.67,P<0.01;Rim为(7.43±0.30)mm,低于正常组的(7.62±0.26)mm,t=-2.505,P<0.01;CCT为(523.74±26.00)μm,低于正常组的(546.25±28.84) μm,t=3.230,P<0.01;角膜前表面K1为(43.58±1.18)D,高于正常组的(42.86±1.43)D,t=2.123,P<0.05;角膜后表面K1为-6.20D(-7.2-5.7D),高于正常组的-6.10 D(-6.6~-5.7 D),Z=101.4,P<0.01;角膜前、后表面陡峭屈光力,角膜前、后表面散光轴向及大小与正常组相比差异无统计学意义.结论 甲状腺相关眼病能引起角膜对称性降低,角膜屈光力增加.%Objective To investigate the effect on cornea topographical characteristcs of thyroid-associated ophthalmology (TAO) disease.Methods In this prospective case control study,46 eyes of 24 patients diagnosed with the inactive TAO were recruited as study

  4. Ocorrência de doenças oftalmológicas em eqüinos utilizados para tração urbana na cidade de Londrina, PR Occurrence of ophthalmologic diseases in horses used for urban cart hauling in Londrina, PR, Brazil

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    Peter Reichmann

    2008-12-01

    Full Text Available Com o objetivo de verificar a ocorrência de doenças oculares em eqüinos utilizados para serviços de tração urbana na cidade de Londrina, PR, foram revistos os registros clínicos de 805 eqüinos atendidos no Hospital Veterinário da Universidade Estadual de Londrina no período entre 1992 e 2007. Nesses registros clínicos foram verificados 25 casos de doenças oftalmológicas (3,1%, compostas por 12 casos (48% de doenças da córnea, seis casos (24% de catarata, seis casos (24% de doenças da conjuntiva (paralelas a outras enfermidades oculares ou não, dois casos (8% de uveíte recorrente eqüina, um caso de carcinoma de células escamosas da terceira pálpebra, um caso de lesão crônica de pálpebra, com necrose e perda do globo ocular, e um caso de Phthisis bulbi (4% cada. A principal causa das enfermidades oftalmológicas diagnosticadas nesses animais foi traumática (36% dos casos. A maioria das doenças diagnosticadas neste estudo, se não tratadas adequadamente, pode resultar em cegueira e, conseqüentemente, pode inutilizar o animal para uso em tração urbana. Isso reforça a necessidade de conscientização dos carroceiros sobre a importância e a profilaxia dessas enfermidades.The clinical records of 805 horses admitted to the Veterinary Hospital of the State University of Londrina between 1992 and 2007 were reviewed in order to establish the occurrence of ophthalmologic diseases in horses used for hauling carts in Londrina, Paraná, Brazil. Among these records, there were 25 ophthalmologic cases (3.1%, composed of 12 cases (48% of corneal diseases, six cases (24% of cataracts, six cases (24% of conjunctival diseases (associated or not to other lesions, two cases (8% of recurrent equine uveitis, one case of squamous cell carcinoma of the third eyelid, one case of chronic necrotic eyelid lesion with loss of the eye globe and one case of phthisis bulbi (4% each. Trauma was the most important etiology for eye diseases diagnosed

  5. Estudo dos achados oculares na síndrome de Stevens-Johnson em pacientes de centro de referência de atendimento terciário Study of the ocular findings in Stevens-Johnson syndrome patients from a tertiary ophthalmologic center

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    Marciel Dourado Franca

    2009-06-01

    : Twenty-two consecutive patients with Stevens-Johnson syndrome were studied. The patients were examined according to the following protocol: identification, previous clinical history, systemic and ophthalmologic manifestations and possible etiologic factors. RESULTS: A total of 22 patients with Stevens-Johnson syndrome were identified. Fifteen patients (68% were female, 7 (32% male. Ten patients were caucasian (45.4%, 9 brownish (22%, 2 black (9% and 1 yellow (4.5%. Mean age was 27.1 (8 to 62. Medications were the most commonly identified etiologic factor (90.9%, followed by skin herpetic infection (4.5% and idiopathic (4.5%. Dipirone (36.3% was the most frequently identified agent, followed by seizure medications (22.7%, non-steroidal anti-inflammatory drugs (13.6%, sulfonamides (9.0%, penicillin (4.5%, spironolactone (4.5% and dihydroprogestagen and stradiol (4.5%. Twenty-one patients (95.4% had ophthalmologic complications and sixteen patients (72.7% underwent ophthalmologic surgical procedures. CONCLUSIONS: The results of this study show important epidemiological aspects of Stevens-Johnson syndrome in our environment, specially related to age, etiology and ocular complications.

  6. Ophthalmology emergency room at the University of São Paulo General Hospital: a tertiary hospital providing primary and secondary level care Pronto-Socorro de Oftalmologia do Hospital das Clinicas da Universidade de São Paulo: um hospital terciário para atendimento de nível primário e secundário

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    Regina de Souza Carvalho

    2007-01-01

    Full Text Available OBJECTIVE: To assess the need for emergency care in a tertiary hospital, in the Ophthalmology Emergency Room of the University of the São Paulo Medical School General Hospital. MATERIALS AND METHODS: A cross-sectional analytic study of the treatment complexity level was carried out in a readily available sample, n = 574, of patients seen at the Ophthalmology Emergency Room of the University of São Paulo Medical School General Hospital, during a typical week. RESULTS: Of the 574 treated patients, 69.0% of the cases were diagnosed as requiring a simple treatment for their problem. The most frequent diagnoses were related to ocular inflammation and infection (55.0%, mainly including conjunctivitis (29.4% and eyelid inflammations (10.5%. Next in frequency were ocular trauma (19.2%, particularly foreign bodies on the cornea (7.5% and blunt trauma (5.2%. Refractive errors (3.1% was the most prevalent diagnosis in the "other ocular modifications" category. CONCLUSION: Most of the cases (69.0% treated at the Ophthalmology Emergency Room of the University of São Paulo Medical School General Hospital could have been diagnosed and treated in primary or secondary care units. Also, the fact that return visits to check recovery are seen in the ER demonstrates the lack of referral services. The fact that patients come to a tertiary hospital with rather simple cases shows the poor structure of the Brazilian Public Healthcare System, which overloads the tertiary care facilities, where costs for human resources, materials, and other items are higher.OBJETIVO: Verificar a necessidade de atendimento em hospital terciário de casos emergenciais do Pronto-Socorro de Oftalmologia do Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo. MATERIAL E MÉTODO: Realizou-se um estudo transversal analítico em amostra prontamente acessível, n= 574, de pacientes emergenciais atendidos no Pronto-Socorro Oftalmológico do Hospital das Clínicas da

  7. Perfil socioeconômico dos portadores de glaucoma no serviço de oftalmologia do hospital universitário da Universidade Federal de Juiz de Fora - Minas Gerais - Brasil Socioeconomic profile of individuals presenting with glaucoma in the service of ophthalmology of the University Hospital of the Federal University of Juiz de Fora - Minas Gerais - Brazil

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    Cristiana Moraes Ramalho

    2007-10-01

    Full Text Available OBJETIVO: Avaliação do perfil socioeconômico dos pacientes portadores de glaucoma primário em acompanhamento no serviço de oftalmologia do hospital universitário da Universidade Federal de Juiz de Fora (MG, Brasil. MÉTODOS: Aplicação de um questionário em 100 pacientes durante suas consultas no serviço de oftalmologia do hospital universitário da Universidade Federal de Juiz de Fora, no período de abril de 2005 a junho de 2006. RESULTADOS: Observou-se que 84% dos pacientes eram pensionistas ou aposentados, 86% recebiam de 1 a 2 salários mínimos, 29% gastavam de 26 a 75 reais/mês com o tratamento do glaucoma, 78% apresentavam co-morbidades e 41% já haviam suspendido o tratamento por falta de condições financeiras para a compra das medicações. CONCLUSÃO: A população em estudo, de baixo nível socioeconômico, apresenta dificuldades de adesão terapêutica por, principalmente, problemas financeiros e presença de co-morbidades. Os autores reforçam a urgente necessidade de adoção de medidas sociopolíticas que facilitem o acesso à medicação antiglaucomatosa, determinando maior aderência terapêutica.PURPOSE: To assess the socioeconomic profile of individuals presenting with primary glaucoma at the ophthalmology service of the university hospital of the Feredal University of Juiz de Fora (MG, Brazil. METHODS: Submission of a questionnaire to 100 individuals during consultation in the ophthalmology service of the university hospital of Federal University of Juiz de Fora (MG, Brazil. RESULTS: Eighty-four per cent of individuals were pensioners or retired, 86% had a monthly income of 1 to 2 salaries, 29% had been spending 26 to 75 reais per month with glaucoma therapy, 78% presented with comorbidities and 41% had already abandoned treatment due to financial difficulties in buying the medication. CONCLUSION: The low-socioeconomic-level studied population presents with therapeutic compliance difficulties mainly due to

  8. Perfil socioeconômico e satisfação dos pacientes atendidos no mutirão de catarata do Instituto da Visão - UNIFESP Socioeconomic profile and satisfaction of individuals attended during the cataract project of the Vision Institute - Ophthalmology department - UNIFESP

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    Luci Meire Pereira da Silva

    2004-10-01

    patients examined during a community project for the treatment of senile cataracts conducted by the Instituto da Visão/Ophthalmology Department - UNIFESP-EPM. METHOD: During the Cataract Project which occurred on 5th Sept, 2002 at the Ophthalmology Department - UNIFESP/EPM, subjects were surveyed by questionnaires developed to identify their socioeconomic characteristics and evaluate their satisfaction regarding attendance. They were randomly selected from the waiting line. RESULTS: The sample was composed of 133 subjects, which represents 50% of patients examined during this Cataract Project. Sixty-one (46% were male and 72 (54% female; 117 (87% were older than 50 years; 111 (84% finished high school; 74 (55% were retired and/or pensioners; 99 (74% had a family income of up to R$ 500,00; 91 (68% needed someone to assist or accompany them during the visit; 95 (71% presented cataract with surgical indication. Regarding their satisfaction with the service, 122 (91% considered the general quality of attendance good; 10 (8% considered it regular and 1 (1% bad. CONCLUSION: As a whole the population examined during this Cataract Project was satisfied with the services, but, some aspects have to be improved to better meet their expectations. It is a needy population, with low visual acuity, depends on public health services, has low level education and, most, need someone to accompany them during the visit to the hospital.

  9. 中医肝脏生理与病理理论对于我国眼科学发展的意义%Significance of the liver physiology and pathology theory of traditional Chinese medicine for ophthalmologic development in China

    Institute of Scientific and Technical Information of China (English)

    郑荣领

    2015-01-01

    antibiotics and immunosuppressive agents, laser and operation therapy can be reduced or even avoided. This can promote the reform of the medical model of ophthalmology, and improve the prevention and control of eye disease in China. The liver physiology and pathology theory of TCM can make great contribution for the ophthalmology development of China as well as the world.

  10. Traumas oculopalpebrais no serviço de pronto-atendimento oftalmológico do Hospital Universitário Evangélico de Curitiba Oculopalpebral traumas in the ophthalmology emergency service of the Evangelic University Hospital of Curitiba

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    Alexey Santos de Andrade

    1999-10-01

    Full Text Available Objetivo: Avaliar o perfil epidemiológico dos pacientes vítimas de traumas oculopalpebrais na cidade de Curitiba. Métodos: Foram estudados, prospectivamente, 622 pacientes que procuraram o Serviço de Pronto-Atendimento Oftalmológico do Hospital Universitário Evangélico de Curitiba no período de março a julho de 1998. Resultados: Houve predomínio de indivíduos do sexo masculino (6 homens: 1 mulher e da faixa etária de 20 a 50 anos, compreendendo 73,3% dos atendimentos. Os traumas oculopalpebrais mais freqüentes foram corpo estranho corneoconjuntival (54,6%, ceratoconjuntivite química (12,1% e trauma contuso (8,8%, sendo que 67,4% dos traumas ocorreram no ambiente de trabalho e 21,2% no ambiente doméstico. Verificou-se que a maioria dos pacientes com trauma oculopalpebral (67% procurou o serviço médico especializado nas primeiras 24 horas pós-trauma, embora a proteção ocular tenha sido pouco utilizada no trabalho e sendo praticamente inexistente em ambiente doméstico. Conclusões: Os autores enfatizam a grande repercussão socioeconômica causada pelos traumas oculopalpebrais e a necessidade de alertar órgãos governamentais, médicos especialistas ou não, representantes de classes, empresários, trabalhadores e a população em geral quanto à importância da prevenção de acidentes oculopalpebrais como forma de proteger a saúde ocular e optimizar os recursos humanos em nossa sociedade.Purpose: To evaluate the epidemiology of patients with oculopalpebral injuries in the city of Curitiba. Methods: We studied, prospectively, 622 patients in the Ophthalmology Emergency Service at the Evangelic Uni-versity Hospital of Curitiba from March to July, 1998. Results: The most affected patients were those between 20 and 50 years of age (73.3% and the males (6 males:1 female. Among the oculopalpebral traumas the most frequent were foreing body (54.6%, chemical keratocon-junctivitis (12.1% and blunt trauma (8.8%. The oculopla

  11. The impact factor and citation frequency of Chinese Journal of Ophthalmology from 2000 to 2009%中华眼科杂志2000至2009年刊出论文的影响因子和被引频次分析

    Institute of Scientific and Technical Information of China (English)

    吴琨芳; 文峰

    2011-01-01

    Objective From the point of impact factor and citation to evaluate the academic level and influence of Chinese Journal of Ophthalmology ( CJO). Methods Using the impact factor (IF) data provided by China Science and Technology Journal Citation Reports ( CJCR),and the information of Chinese Medical citation Index (CMCI/CMCC integrated version),the citations from C JO were collected and analyzed with bibliometric methods. Result From 2000 to 2008,the IF of CJO were 0. 573,0. 863,0. 702,0. 745,0. 877,1. 031,0. 807,0. 875 and 0. 533. From 2000 to 2009,2485 papers were published in CJO,1562 of them were referenced (9294 times). The frequency of total citation rate was 62. 86%. The region with the highest citation frequency was Guangdong ( 2661 times),followed by Beijing ( 2200 times),Shandong (926 times) and Shanghai(901 times). As to the institution,the top of rank was Zhongshan Ophthalmic Center of Sun Yat-Sen University (with 277 papers,201 citations and 2193 times of citation frequency) and Beijing Tongren Eye Center ( with 197 papers,106 citations and 507 times of citation frequency). Conclusion The IF of CJO was stable,and ranked first in domestic academic of Ophthalmology. Meanwhile,it had a higher frequency of Citation,which shows that CJO has high quality and strong influence,and become one of main core ophthalmology journals in China.%目的 从影响因子及文献引证角度研究中华眼科杂志的学术水平和影响力.方法 依据(CJCR)提供的影响因子数据,并按照文献计量学的方法,利用(CMCI/CMCC整合版)的资料和数据,对中华眼科杂志载文被CMCI/CMCC来源期刊引用的情况进行统计分析和评价.结果 中华眼科杂志自2000年至2008年的影响因子分别为0.573、0.863、0.702、0.745、0.877、1.031、0.807、0.875、0.533.2000年至2009年近十年共刊出论文2485篇,被引用1562篇,总被引频次为9294次,总被引率为62.86%.按被引文章作者地区划分,广东、北京、山东和上海

  12. Distrofia retiniana com onda rápida escotópica (DRORE associada à síndrome dos cabelos anágenos frouxos (SCAF. Parte I: Achados oftalmológicos Scotopic fast wave retinal dystrophy (SFWRD associated with loose anagen hair syndrome (LAHS. Part I: Ophthalmological findings

    Directory of Open Access Journals (Sweden)

    Mário Teruo Sato

    2004-06-01

    ópica associada à síndrome dos cabelos anágenos frouxos, distrofia cujos achados fundoscópicos são diferentes entre homens e mulheres e com traçado eletrorretinográfico característico.PURPOSE: To describe the ophthalmological findings of a new macular dystrophy associated with loose anagen hair syndrome (LAHS. METHODS: Eleven patients of the same family, four of whom presented ocular abnormalities, were examined. Seven patients were submitted to the following examinations: a complete ophthalmological examination, color test, ultrasonography, angiography, visual field, optic disc topography, electro-oculogram (EOG, electroretinogram (ERG, laboratory and dermatological tests, sweat testing, light microscopy (LM and scanning electron microscopy (SEM of the scalp hair. In four patients, children of affected, examination was restricted to an ophthalmological examination and light microscopy and the scanning electron microscopy of the scalp hair. RESULTS: Of the four affected patients, two affected sisters showed pigmentary dispersions in the posterior pole of the retina with macular coloboma. Two brothers showed pigmentary dispersions in the posterior pole, with greater pigmentation and a yellowish aspect of the macular area without coloboma. The results of the ectro-oculogram and electroretinogram were within normal limits in three patients without ocular abnormalities. Whereas, electro-oculogram was subnormal and electroretinogram was subnormal with short implicit time (fast in the scotopic phase of the patients with the macular dystrophy, suggesting that the site of this dystrophy is at the level of the retinal pigment epithelium. Due to this peculiar behavior of the implicit time of the wave, such finding can be considered as fundamental to make the diagnosis of this dystrophy. The denomination could be scotopic fast wave retinal dystrophy (SFWRD. Light microscopy and scanning electron microscopy of scalp hair confirmed the loose anagen hair syndrome. CONCLUSIONS: We

  13. A CASE OF CHRONIC SPHENOIDITIS WITH NEUROLOGIC AND OPHTHALMOLOGIC COMPLICATIONS

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    M. Yu. Bobylova

    2012-01-01

    Full Text Available A case of chronic sphenoidal sinusitis in a girl of 9 years old is proposed; in clinical picture oculomotor dysfunction occurred (ptosis, strabismus divergent, diplopia, epiphora. The condition was masked by neurological symptoms, and so initial differential diagnosis was between 1 ocular form of myopathy (including mitochondrial diseases, 2 ocular form of myasthenia and 3 onset of multiple sclerosis. The definite diagnosis «pansinusitis» was proposed by neurologist only after attentive analysis of clinical symptoms and data of MRI, only since 1,5 year after beginning of the disease. This clinical case demonstrates the complexity of differential diagnosis of chronic sphenoidal sinusitis in children and necessity of developed clinical thinking for a doctor of every speciality

  14. glaucoma proceedingings of the ophthalmological society of nigeria ...

    African Journals Online (AJOL)

    2016-11-04

    VCDR difference of 0.2 and above and were considered Glaucoma. Suspects ... and Intraocular Pressure in Primary Open Angle Glaucoma ... [Downloaded free from http://www.nigerianjournalofophthalmology.com on Friday, November 04, 2016, ..... and shots used was 1535.4 mW and 47.9 (seeing eyes) and 1616.7.

  15. Intraoperative flap complications in lasik surgery performed by ophthalmology residents

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    Lorena Romero-Diaz-de-Leon

    2016-01-01

    Conclusion: Flap-related complications are common intraoperative event during LASIK surgery performed by in-training ophthalmologists. Keratometries and surgeon's first procedure represent a higher probability for flap related complications than some other biometric parameters of patient's eye.

  16. Different causes of referral to ophthalmology emergency room

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    Alireza Keshtkar Jafari

    2012-01-01

    Full Text Available Background: Eye-related complaints compose approximately 1-6% of complaints of patients referring to general emergency ward around the world. Eye injuries are the most common cause of referral to eye emergency ward. To understand the impact of eye injuries in Iran and to plan preventive strategies, it is important to understand the complete magnitude of the problem with regard to true population-based data and standard reproducible definitions. Aim: The main goal of this study was to identify the major causes of referrals to eye emergency ward in patients with eye-related complaints in an eye referral Hospital in Iran. Settings and Design: In a cross-sectional study, 3150 patients who referred to Farabi Hospital emergency ward, Tehran, Iran, from January to December 2007 were included in the study and their detailed information were recorded. Materials and Methods: The patients′ demographic data, medical history and final diagnosis were recorded in a questionnaire. Results: The mean age of patients was 33.2±16.8 years and 2380 patients (75.6% were males. While 299 patients (9.5% were referred for non-urgent reasons, work-related injuries were the most common cause of referral (955 patients; 30.3%. In patients referred due to trauma (1950 patients, work-related injuries occurred in 955 patients (49% and occurred accidentally (by chance in 819 patients (42%. The majority of patients referred with traumatic injuries were males (1708 patients; 87.6% versus 242 patients; 12.4%. The most common etiologies of eye trauma (1950 patients were metal filings (814 patients; 41.8%, blunt trauma (338 patients; 17.3%, fireworks (236 patients; 12.1% and sharp objects (222 patients; 11.4%. Globe injury was diagnosed in 1865 patients (95.7% of trauma cases. In patients referred due to non-traumatic reason (1200 patients, eye infection occurred in 482 patients (40.2% and 299 patients (24.9% were referred for non-urgent reasons. There was little difference between the frequency of non-trauma-related problems among genders (672 male patients; 56% versus 528 female patients; 44%. Conclusions: This study identified multiple risk factors whose presence significantly increases severity of an eye injury. Male gender, youth and unprotected eyes during high-risk activities such as sports and certain jobs are risk factors for eye injuries. In patients referred due to non-traumatic reasons, males and females are similar. Considerable proportion of non-trauma-related problems was due to eye infection, that one of the most important reasons may be connected to the increasing use of contact lenses in our target population. Thereupon, we need for further educative and preventive interventions at the level of general population.

  17. Vision Integrating Strategies in Ophthalmology and Neurochemistry (VISION)

    Science.gov (United States)

    2015-05-01

    hypertension ). We have developed techniques to quantify damage to the retina, optic nerve, and visual axis in the brain (i.e. superior colliculus) that...3 Introduction ………………………………………………………………………………….4 Key Words …………………………………………………………………………………..5 Overall Project Summary...ischemia/reperfusion, and chronic ocular hypertension ). We developed techniques to quantify damage to the retina, optic nerve, and visual axis in the brain

  18. Different causes of referral to ophthalmology emergency room

    Science.gov (United States)

    Jafari, Alireza Keshtkar; Bozorgui, Shima; Shahverdi, Nooshin; Ameri, Ahmad; Akbari, Mohammad Reza; Salmasian, Hojat

    2012-01-01

    Background: Eye-related complaints compose approximately 1–6% of complaints of patients referring to general emergency ward around the world. Eye injuries are the most common cause of referral to eye emergency ward. To understand the impact of eye injuries in Iran and to plan preventive strategies, it is important to understand the complete magnitude of the problem with regard to true population-based data and standard reproducible definitions. Aim: The main goal of this study was to identify the major causes of referrals to eye emergency ward in patients with eye-related complaints in an eye referral Hospital in Iran. Settings and Design: In a cross-sectional study, 3150 patients who referred to Farabi Hospital emergency ward, Tehran, Iran, from January to December 2007 were included in the study and their detailed information were recorded. Materials and Methods: The patients’ demographic data, medical history and final diagnosis were recorded in a questionnaire. Results: The mean age of patients was 33.2±16.8 years and 2380 patients (75.6%) were males. While 299 patients (9.5%) were referred for non-urgent reasons, work-related injuries were the most common cause of referral (955 patients; 30.3%). In patients referred due to trauma (1950 patients), work-related injuries occurred in 955 patients (49%) and occurred accidentally (by chance) in 819 patients (42%). The majority of patients referred with traumatic injuries were males (1708 patients; 87.6% versus 242 patients; 12.4%). The most common etiologies of eye trauma (1950 patients) were metal filings (814 patients; 41.8%), blunt trauma (338 patients; 17.3%), fireworks (236 patients; 12.1%) and sharp objects (222 patients; 11.4%). Globe injury was diagnosed in 1865 patients (95.7%) of trauma cases. In patients referred due to non-traumatic reason (1200 patients), eye infection occurred in 482 patients (40.2%) and 299 patients (24.9%) were referred for non-urgent reasons. There was little difference between the frequency of non-trauma-related problems among genders (672 male patients; 56% versus 528 female patients; 44%). Conclusions: This study identified multiple risk factors whose presence significantly increases severity of an eye injury. Male gender, youth and unprotected eyes during high-risk activities such as sports and certain jobs are risk factors for eye injuries. In patients referred due to non-traumatic reasons, males and females are similar. Considerable proportion of non-trauma-related problems was due to eye infection, that one of the most important reasons may be connected to the increasing use of contact lenses in our target population. Thereupon, we need for further educative and preventive interventions at the level of general population. PMID:22416149

  19. The Decompensated Monofixation Syndrome (An American Ophthalmological Society Thesis)

    Science.gov (United States)

    Siatkowski, R. Michael

    2011-01-01

    Purpose To describe the clinical features and response to treatment of patients with decompensated monofixation syndrome (MFS) and to propose a hypothesis for a decompensation mechanism in such patients. Methods Fourteen adults with MFS who had been symptomatically stable for a mean duration of 25 years developed diplopia in the absence of neurologic or orbital disease. After retrospective chart review, they underwent detailed orthoptic testing. Results from this cross-sectional analysis were compared with similar data from 16 control subjects with stable MFS. Results Compared to stable MFS patients, decompensated subjects had significantly poorer horizontal fusional amplitudes but greater torsional fusional amplitudes; they were also more likely to have a small vertical strabismus and to have received initial treatment later. Stable subjects, however, also had subnormal horizontal as well as torsional fusional amplitudes. There was no difference between groups with respect to refractive error, amblyopia, type or prior treatment of strabismus, stereoacuity, or angle of deviation. After treatment, all patients regained monofixational alignment, but up to one-third had continued diplopia. Symptoms recurred in two patients whose treatment was initially successful. Conclusions Patients with MFS lose fusional amplitudes over time. In some cases this results in development of sensory torsion with secondary decompensation and diplopia. The rate of decompensation averages 7% per year from ages 20 to 70. Treatment for decompensation offers excellent motor results, but sensory symptoms may persist and recurrent symptoms may develop. Monitoring and maintenance of fusional vergence amplitudes should be part of the routine care for patients with MFS. PMID:22253490

  20. Ophthalmologic findings in patients with inborn errors of metabolism

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    Guevara Márquez Yamel Carolina

    2014-07-01

    Full Text Available In patient with inborn errors of metabolism (IEM, the presence of characteristic findings in ophthalmic assessment are important for the diagnosis. The presence of cataracts, cherry-red spot, corneal opacities, corneal crystals, lens dislocation, gyrate atrophy, etc., are some of the ocular abnormalities present in certain IEM. The role of the ophthalmologist in the evaluation of patients with IEM is essential. We describe the most frequent ocular findings in patients with different IEM, which are a diagnostic aid for ophthalmologists and pediatricians.

  1. [Systemic and ophthalmological findings in Cornelia de Lange syndrome].

    Science.gov (United States)

    Mrugacz, Małgorzata; Sielicka, Danuta

    2012-01-01

    Cornelia de Lange Syndrome (CdLS, de Lange syndrome, Brachmann-de Lange syndrome), is a relatively rare genetic disorder, characterized by set of clinical abnormalities concerning different organs and systems. Phenotypic diagnosis is based on a specific dysmorphic features seen after the birth. We described a genetic basis, hereditary patterns, characteristic dysmorphic features and the most common clinical findings of patients Cornelia de Lange Syndrome concerning eye and vision, hearing, cardiovascular, respiratory, gastrointestinal, genitourinary, skeletal and psychomotor development.

  2. [Endocrine ophthalmology. An overview of pathology, classification, and therapy].

    Science.gov (United States)

    Bürgi, H; König, M P

    1975-08-30

    A new uniform nomenclature will allow more accurate clinical study of endocrine ophthalmopathy, a disease that remains an enigma. Clinical eye disease develops in 30-60% of patients with Graves' disease, but the severe malignant form occurs in a maximum of 5%, and most of these latter patients have been rendered euthyroid or hypothyroid by treatment of the hyperthyroidism. Despite claims to the contrary, there is no convincing evidence that the mode of treatment (antithyroid drugs, surgery or radioiodine) has a bearing on the development of ophthalmopathy. Circulating fragments of the TSH-molecule, which produce swelling of retroorbital tissue, and as autoimmune processes of the delayed type are currently under consideration as causative factors. Medical treatment of endocrine ophthalmopathy has only a limited effect. In cases of rapid progression with deterioration of vision it is recommended that operative decompression, preferably into the maxillary and ethmoidal sinus, be performed without delay. Retroorbital administration of 2000 rad by a highly collimated megavoltage beam appears to be a valuable alternative to surgery.

  3. Adaptive optics ophthalmologic systems using dual deformable mirrors

    Energy Technology Data Exchange (ETDEWEB)

    Jones, S; Olivier, S; Chen, D; Sadda, S; Joeres, S; Zawadzki, R; Werner, J S; Miller, D

    2007-02-01

    Adaptive Optics (AO) have been increasingly combined with a variety of ophthalmic instruments over the last decade to provide cellular-level, in-vivo images of the eye. The use of MEMS deformable mirrors in these instruments has recently been demonstrated to reduce system size and cost while improving performance. However, currently available MEMS mirrors lack the required range of motion for correcting large ocular aberrations, such as defocus and astigmatism. In order to address this problem, we have developed an AO system architecture that uses two deformable mirrors, in a woofer/tweeter arrangement, with a bimorph mirror as the woofer and a MEMS mirror as the tweeter. This setup provides several advantages, including extended aberration correction range, due to the large stroke of the bimorph mirror, high order aberration correction using the MEMS mirror, and additionally, the ability to ''focus'' through the retina. This AO system architecture is currently being used in four instruments, including an Optical Coherence Tomography (OCT) system and a retinal flood-illuminated imaging system at the UC Davis Medical Center, a Scanning Laser Ophthalmoscope (SLO) at the Doheny Eye Institute, and an OCT system at Indiana University. The design, operation and evaluation of this type of AO system architecture will be presented.

  4. Genetics in Ophthalmology II–Anterior Segment Diseases

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    Canan Aslı Utine

    2012-10-01

    Full Text Available Genetic diseases are congenital or acquired hereditary diseases that result from structural/functional disorders of the human genome. Today, the genetic factors that play a role in many diseases are being highlighted with the rapid progress in the field of genetics science. It becomes increasingly important that physicians from all disciplines have knowledge about the basic principles of genetics, patterns of inheritance, etc., so that they can follow the new developments. In genetic eye diseases, ophthalmologists should know the basic clinical and recently rapidly developing genetic characteristics of these diseases in order to properly approach the diagnosis and treatment and to provide genetic counseling. In this paper, anterior segment eye diseases of genetic origin are reviewed, and aniridia, anterior segment dysgenesis, glaucoma, corneal dystrophies, cataract, ectopia lentis, myopia, and other refractive errors are covered. (Turk J Ophthalmol 2012; 42: 378-85

  5. Discordant Dry Eye Disease (An American Ophthalmological Society Thesis).

    Science.gov (United States)

    Shtein, Roni M; Harper, Daniel E; Pallazola, Vincent; Harte, Steven E; Hussain, Munira; Sugar, Alan; Williams, David A; Clauw, Daniel J

    2016-08-01

    To improve understanding of dry eye disease and highlight a subgroup of patients who have a component of central sensitization and neuropathic pain contributing to their condition. Prospective, cross-sectional, IRB-approved study comparing isolated dry eye disease (n=48) to fibromyalgia (positive control; n=23) and healthy (negative control; n=26) individuals with ocular surface examination, corneal confocal microscopy, quantitative sensory testing, and self-reported ocular symptoms and systemic associations. A subset of patients also underwent skin biopsy and/or brain neuroimaging. Dry eye patients were split into concordant (ie, those with dry eyes on examination) and discordant (ie, those with dry eye symptoms but normal examination) subgroups for further analysis. We hypothesized that on the systemic measures included, concordant patients would resemble healthy controls, whereas discordant patients would show evidence of centralized mechanisms similar to fibromyalgia. Schirmer test and Ocular Surface Disease Index (OSDI) scores indicated significant decreases in tear production (Schirmer: healthy, 18.5±8.2 mm; dry, 11.2±5.4 mm; fibromyalgia, 14.4±7.5; P<.001) and increases in self-reported dry eye symptoms (OSDI: healthy, 1.9±3.0; dry, 20.3±17.7; fibromyalgia, 20.3±17.1; P<.001) in the dry eye and fibromyalgia patients, compared to controls. The discordant subgroup had decreased corneal nerve density and decreased visual quality-of-life scores, similar to patients with fibromyalgia. Concordant patients were more similar to healthy controls on these measures. Individuals with discordant dry eye may have a central pathophysiologic mechanism leading to their eye pain symptoms, which could be an important factor to consider in treatment of chronic idiopathic dry eye.

  6. Adalimumab (Humira TM in ophthalmology: A review of the literature

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    Neri Piergiorgio

    2010-01-01

    Full Text Available Tumor Necrosis Factor alpha (TNF-α is a pleiotropic cytokine which plays a primary role in the induction of inflammation in autoimmune diseases. The newest anti-TNF-α agent is adalimumab (Humira, Abbott Pharmaceutical Inc., a human-derived antibody. This review summarizes the characteristics of adalimumab, highlighting its clinical use in systemic and ocular inflammatory disorders, and the possible therapeutic strategies. Adalimumab has been successfully used for the treatment of rheumatoid arthritis, ankylosing spondylitis, and psoriasis arthritis. More recently, adalimumab has shown promising qualities in controlling intraocular inflammations, even though this has been used prevalently as a rescue therapy for unresponsive cases. This biologic agent was also used in pediatric cases, showing a good safety and efficacy profile. Albeit no direct comparison with other biologics has been done, and adalimumab seems to be equivalent to the other anti-TNF-α, the switching to adalimumab can offer a better uveitic control. Adalimumab is a promising drug for the treatment of uveitis, even though further studies are needed on its application as a primary therapy in uveitis.

  7. LASER CORRELATION SPECTROSCOPY (LCS) AND ITS CLINICAL PERSPECTIVES IN OPHTHALMOLOGY

    OpenAIRE

    Karganov Mikhail; Eskina Erika; Stepanova Maria

    2015-01-01

    The method of laser correlation spectroscopy (LCS) is based on the analysis of the spectrum of quasielastic light scatter during coherent monochromatic laser irradiation of micro-particles in biological fluids (blood serum, urine, oropharyngeal washout fluid, tear fluid etc.). Spectrum provides information on dynamic processes in the analyzed system: translation motion of scattering particles and their orientation and conformation dynamics. Special procedures of cluster analysis make it possi...

  8. Surgery in World War II. Ophthalmology and Otolaryngology

    Science.gov (United States)

    1957-01-01

    hWO -- -------------- Marcl 1945 ----- 250) 250 553 I tw1m~ing twIin s for hi join I casualtivs amot eastialits recquiriav plistic surgery.I includring...Reliahilitat ion Center, Borden General H ospjit al. Thet wall chart shows thle V-posit ion assumed 1) the mnomt .i inl thle Ipromnnci:ittion of vowels

  9. BW - Decision support in ophthalmology: blueWorks

    OpenAIRE

    Reis, Pedro Manuel Almeida dos

    2010-01-01

    Sendo a saúde uma área muito exigente é, no entanto, também uma área de oportunidades se tivermos em conta as necessidades e dificuldades que, quem vive e trabalha na área, todos os dias enfrenta. A criação de soluções que permitam agilizar o processo de prestação de cuidados de saúde, de dar apoio ao diagnóstico de pacientes ou de facilitar o cruzamento e armazenamento de informação, etc., é sem dúvida uma perspectiva aliciante para quem, como eu, trabalha na área da engenharia biomédica. No...

  10. Neuro-ophthalmologic complications of neoplastic leptomeningeal disease.

    Science.gov (United States)

    Szatmáry, Gabriella

    2013-12-01

    Neoplastic leptomeningeal disease (NLD), which encompasses both primary and secondary leptomeningeal tumors, has a devastating impact on the life of cancer patients. The present diagnostic technical armamentarium is insufficient for early diagnosis of NLD. However, NLD may present with subtle neuro-ophthalmic features at a time of relatively small tumor burden, which gives the provider first encountering these patients the window of opportunity for early diagnosis and consequently improved life expectancy and quality of life of these patients. Therefore, familiarity with early, often subtle neuro-ophthalmic features is an essential tool for diagnosing these patients prior to the development of fixed deficits, which usually portend a dismal prognosis. Future evolving laboratory and neuroimaging technologies are expected to advance our understanding of underlying pathophysiology and early detection of NLD. This paper provides an up-to-date review and synthesis of the current literature with focus on neuro-ophthalmic features and their underlying pathophysiology.

  11. The stem cell and tissue engineering research in Chinese ophthalmology

    Institute of Scientific and Technical Information of China (English)

    GE Jian; LIU Jingbo

    2007-01-01

    Much has been considerably developed recently in the ophthalmic research of stem cell (SC) and tissue engineering (TE).They have become closer to the clinical practice,standardized and observable.Leading edge research of SC and TE on the ocular surface reconstruction,neuroregeneration and protection,and natural animal model has become increasingly available.However,challenges remain on the way,especially on the aspects of function reconstruction and specific differentiation.This paper reviews the new developments in this area with an intention of identifying research priorities for the future.

  12. Vasoactive neuropeptides in clinical ophthalmology: An association with autoimmune retinopathy?

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    Donald R Staines

    2009-03-01

    Full Text Available Donald R Staines1,2, Ekua W Brenu2, Sonya Marshall-Gradisnik21Queensland Health, Gold Coast Population Health Unit, Southport, Gold Coast, Queensland, Australia; 2Faculty of Health Science and Medicine, Population Health and Neuroimmunology Unit, Bond University, Robina, Queensland, AustraliaAbstract: The mammalian eye is protected against pathogens and inflammation in a relatively immune-privileged environment. Stringent mechanisms are activated that regulate external injury, infection, and autoimmunity. The eye contains a variety of cells expressing vasoactive neuropeptides (VNs, and their receptors, located in the sclera, cornea, iris, ciliary body, ciliary process, and the retina. VNs are important activators of adenylate cyclase, deriving cyclic adenosine monophosphate (cAMP from adenosine triphosphate (ATP. Impairment of VN function would arguably impede cAMP production and impede utilization of ATP. Thus VN autoimmunity may be an etiological factor in retinopathy involving perturbations of purinergic signaling. A sound blood supply is necessary for the existence and functional properties of the retina. This paper postulates that impairments in the endothelial barriers and the blood–retinal barrier, as well as certain inflammatory responses, may arise from disruption to VN function. Phosphodiesterase inhibitors and purinergic modulators may have a role in the treatment of postulated VN autoimmune retinopathy.Keywords: retinopathy, autoimmune, vasoactive neuropeptides, phosphodiesterase inhibitors

  13. An Update on the Ophthalmologic Features in the Phakomatoses

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    Solmaz Abdolrahimzadeh

    2016-01-01

    Full Text Available Neurofibromatosis type 1, tuberous sclerosis complex, and Von Hippel-Lindau disease, historically classified as the phakomatoses, are hereditary multisystem disorders characterized by the presence of hamartoma, which carry the risk of malignant transformation. The alteration of tumor suppressor genes seems to be at the basis of their pathophysiogenetic mechanism. Lisch and choroidal nodules in neurofibromatosis type 1, retinal astrocytomas in tuberous sclerosis complex, and retinal capillary hemangioma in Von Hippel-Lindau disease are the principal ophthalmic hamartomatous manifestations. The advent of novel imaging techniques such as near infrared reflectance and optical coherence tomography has provided unprecedented insight on the choroidal and retinal features of these diseases. These methods have improved early diagnosis and the ongoing surveillance in these conditions. Among an array of treatment modalities, antivascular endothelial growth factor therapy has been used in the management of retinal hamartomas but results have been varied. This review is an update on the pathophysiogenetic mechanisms, ophthalmic manifestations, and novel treatment strategies in the phakomatoses with emphasis on the role of imaging techniques.

  14. Step-by-step phacoemulsification training program for ophthalmology residents

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    Wang Yulan

    2013-01-01

    Full Text Available Aims: The aim was to analyze the learning curve of phacoemulsification (phaco performed by residents without experience in performing extra-capsular cataract extraction (ECCE in a step-by-step training program (SBSTP. Materials and Methods: Consecutive surgical records of phaco performed from March 2009 to Sept 2011 by four residents without previous ECCE experience were retrospectively reviewed. The completion rate of the first 30 procedures by each resident was calculated. The main intraoperative phaco parameter records for the first 30 surgeries by each resident were compared with those for their last 30 surgeries. Intraoperative complications in the residents′ procedures were also recorded and analyzed. Results: A total of 1013 surgeries were performed by residents. The completion rate for the first 30 phaco procedures was 79.2 μ 5.8%. The main reasons for halting the procedure were as follows: Anterior capsule tear, inability to crack the nucleus, and posterior capsular rupture during phaco or cortex removal. Cumulative dissipated energy of phaco power used during the surgeries was significantly less in the last 30 cases compared with the first 30 cases (30.10 μ 17.58 vs. 55.41 μ 37.59, P = 0.021. Posterior capsular rupture rate was 2.5 μ 1.2% in total (10.8 μ 4.2% in the first 30 cases and 1.7 μ 1.9% in the last 30 cases, P = 0.008; a statistically significant difference. Conclusion:The step-by-step training program might be a necessary process for a resident to transit from dependence to a self-supported operator. It is also an essential middle step between wet lab training to performing the entire phaco procedure on the patient both effectively and safely.

  15. Traditional medicine in Oman: Its role in ophthalmology

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    Al Barwani Badar

    2009-01-01

    Full Text Available Aim: To present three patients with ocular disease who developed a range of complications following use of traditional medications. Settings and Design: Case series Methods: Three patients who were examined in the Ophthalmic department of a tertiary care teaching hospital in the Sultanate of Oman between 2003 and 2004, seeking care following use of traditional medicines and or healing practices for various ophthalmic problems described below. Results: The first patient was a computer professional with a chalazion; the patient used a plant extract from ′Calotropis procera′ as a part of the treatment. He developed corneal edema with decrease in vision in his left eye following application of the plant extract. Treatment with topical steroids and antibiotics resulted in a complete clinical and visual recovery. The second patient developed a fungal corneal ulcer (dermatophyte - Trichophyton mentagrophyte after sustaining injury with an animal tail to the right eye and used honey for pain relief prior to presentation. She responded poorly to anti-fungal treatment, underwent a penetrating keratoplasty with recurrence of infection in the graft that resulted in a vascularized corneal scar. The third patient was a five-year-old child who was treated with ′wasam′ on the occiput for intraocular inflammation following bilateral uncomplicated cataract extraction. Following this treatment the topical steroid was discontinued. The "Wasam" treatment indirectly resulted in exacerbation of the intraocular inflammation and secondary glaucoma and poor vision as well as ′Wasam ulcers′ on the occiput. Despite treatment of the intraocular inflammation, the visual outcome was poor. Conclusion: Traditional medicine in Oman is sought by many for variable reasons. Lack of evidence-based scientific data on its safety or efficacy does not deter the Omanis from flocking the traditional healers. However, when applied in the treatment of ocular diseases, traditional medicine and healing practices seem to cause more harm than benefit for the patient.

  16. Principles and practice of external digital photography in ophthalmology

    Science.gov (United States)

    Mukherjee, Bipasha; Nair, Akshay Gopinathan

    2012-01-01

    It is mandatory to incorporate clinical photography in an ophthalmic practice. Patient photographs are routinely used in teaching, presentations, documenting surgical outcomes and marketing. Standardized clinical photographs are part of an armamentarium for any ophthalmologist interested in enhancing his or her practice. Unfortunately, many clinicians still avoid taking patient photographs for want of basic knowledge or inclination. The ubiquitous presence of the digital camera and digital technology has made it extremely easy and affordable to take high-quality images. It is not compulsory to employ a professional photographer or invest in expensive equipment any longer for this purpose. Any ophthalmologist should be able to take clinical photographs in his/her office settings with minimal technical skill. The purpose of this article is to provide an ophthalmic surgeon with guidelines to achieve standardized photographic views for specific procedures, to achieve consistency, to help in pre-operative planning and to produce accurate pre-operative and post-operative comparisons, which will aid in self-improvement, patient education, medicolegal documentation and publications. This review also discusses editing, storage, patient consent, medicolegal issues and importance of maintenance of patient confidentiality. PMID:22446907

  17. Principles and practice of external digital photography in ophthalmology

    Directory of Open Access Journals (Sweden)

    Bipasha Mukherjee

    2012-01-01

    Full Text Available It is mandatory to incorporate clinical photography in an ophthalmic practice. Patient photographs are routinely used in teaching, presentations, documenting surgical outcomes and marketing. Standardized clinical photographs are part of an armamentarium for any ophthalmologist interested in enhancing his or her practice. Unfortunately, many clinicians still avoid taking patient photographs for want of basic knowledge or inclination. The ubiquitous presence of the digital camera and digital technology has made it extremely easy and affordable to take high-quality images. It is not compulsory to employ a professional photographer or invest in expensive equipment any longer for this purpose. Any ophthalmologist should be able to take clinical photographs in his/her office settings with minimal technical skill. The purpose of this article is to provide an ophthalmic surgeon with guidelines to achieve standardized photographic views for specific procedures, to achieve consistency, to help in pre-operative planning and to produce accurate pre-operative and post-operative comparisons, which will aid in self-improvement, patient education, medicolegal documentation and publications. This review also discusses editing, storage, patient consent, medicolegal issues and importance of maintenance of patient confidentiality.

  18. Smart ophthalmics: the future in tele-ophthalmology has arrived

    Science.gov (United States)

    Fink, Wolfgang; Tarbell, Mark A.; Garcia, Kevin

    2016-05-01

    Smart Ophthalmics© extends ophthalmic healthcare to people who operate/live in austere environments (e.g., military, third world, natural disaster), or are geographically dispersed (e.g., rural populations), where time, cost, and the possibility of travel/transportation make access to even adequate medical care difficult, if at all possible. Operators attach optical devices that act as ophthalmic examination extensions to smartphones and run custom apps to perform examinations of specific areas of the eye. The smartphone apps submit over wireless networks the collected examination data to a smart remote expert system, which provides in-depth medical analyses that are sent back in near real-time to the operators for subsequent triage.

  19. LEAN SIX SIGMA TECHNIQUES TO IMPROVE OPHTHALMOLOGY CLINIC EFFICIENCY.

    Science.gov (United States)

    Ciulla, Thomas A; Tatikonda, Mohan V; ElMaraghi, Yehya A; Hussain, Rehan M; Hill, Amanda L; Clary, Julie M; Hattab, Eyas

    2017-07-18

    Ophthalmologists serve an increasing volume of a growing elderly population undergoing increasingly complex outpatient medical care, including extensive diagnostic testing and treatment. The resulting prolonged patient visit times ("patient flow times") limit quality, patient and employee satisfaction, and represent waste. Lean Six Sigma process improvement was used in a vitreoretinal practice to decrease patient flow time, demonstrating that this approach can yield significant improvement in health care. Process flow maps were created to determine the most common care pathways within clinic. Three months' visits from the electronic medical record system, which tracks patient task times at each process step in the office were collected. Care tasks and care pathways consuming the greatest time and variation were identified and modified. Follow-up analysis from 6 weeks' visits was conducted to assess improvement. Nearly all patients took one of five paths through the office. Patient flow was redesigned to reduce waiting room time by having staff members immediately start patients into one of those five paths; staffing was adjusted to address high demand tasks, and scheduling was optimized around derived predictors of patient flow times. Follow-up analysis revealed a statistically significant decline in mean patient flow time by 18% and inpatient flow time SD by 4.6%. Patient and employee satisfaction scores improved. Manufacturing industry techniques, such as Lean and Six Sigma, can be used to improve patient care, minimize waste, and enhance patient and staff satisfaction in outpatient clinics.

  20. Principles and practice of external digital photography in ophthalmology.

    Science.gov (United States)

    Mukherjee, Bipasha; Nair, Akshay Gopinathan

    2012-01-01

    It is mandatory to incorporate clinical photography in an ophthalmic practice. Patient photographs are routinely used in teaching, presentations, documenting surgical outcomes and marketing. Standardized clinical photographs are part of an armamentarium for any ophthalmologist interested in enhancing his or her practice. Unfortunately, many clinicians still avoid taking patient photographs for want of basic knowledge or inclination. The ubiquitous presence of the digital camera and digital technology has made it extremely easy and affordable to take high-quality images. It is not compulsory to employ a professional photographer or invest in expensive equipment any longer for this purpose. Any ophthalmologist should be able to take clinical photographs in his/her office settings with minimal technical skill. The purpose of this article is to provide an ophthalmic surgeon with guidelines to achieve standardized photographic views for specific procedures, to achieve consistency, to help in pre-operative planning and to produce accurate pre-operative and post-operative comparisons, which will aid in self-improvement, patient education, medicolegal documentation and publications. This review also discusses editing, storage, patient consent, medicolegal issues and importance of maintenance of patient confidentiality.

  1. The impact of information technology on the practice of ophthalmology.

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    Prasad Somdutt

    2000-01-01

    Full Text Available Information technology has had a tremendous impact on the outlook of our professional lives. The Internet has revolutionised the speed of access to information with touch of a button. This article discusses the various aspects of information technology which are changing and enhancing our professional lives. It provides tips to enable the busy practising clinician to use the available resources effectively. Problems such as reliability of information on the web and how to assess the quality of such matter are also discussed.

  2. Systemic and Ophthalmologic Findings in Patients with Iris Coloboma

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    Sevda Ertekin

    2013-01-01

    Full Text Available Pur po se: Ocular coloboma is a rare malformation resulting from defective closure of the embryonic optic fissure. It can affect iris, retina, choroid, optic disc or ciliary body. This study reviews the clinical diagnosis and the accompanying ocular and systemic abnormalities in cases of iris coloboma. Ma te ri al and Met hod: Sixteen eyes of ten patients referred to our clinic and diagnosed as iris coloboma were included in the study and were reviewed retrospectively. Re sults: Seven cases were sporadic, and three cases were familial. Isolated iris coloboma was present in only one case, and chorioretinal involvement was present in all the others. Seven cases had involvement of the optic disc. Other ocular anomalies were unilateral microphthalmia in 3 cases, unilateral anophthalmia in 1 case, and unilateral microcornea in one case. Strabismus was present in the familial cases. Dis cus si on: In patients, diagnosed with iris coloboma, routine eye examination should be completed, refractive errors should be corrected, and these patients must be follewed for amblyopia. If strabismus is concominant, surgery can be performed. For potential complications, patients should be checked at regular intervals. (Turk J Ophthalmol 2013; 43: 19-22

  3. Genetics in Ophthalmology III – Posterior Segment Diseases

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    Canan Aslı Utine

    2012-10-01

    Full Text Available Genetic diseases are congenital or acquired hereditary diseases that result from structural/functional disorders of the human genome. Today, the genetic factors that play a role in many diseases are being highlighted with the rapid progress in the field of genetics science. It becomes increasingly important that physicians from all disciplines have knowledge about the basic principles of genetics, patterns of inheritance, etc., so that they can follow the new developments. In genetic eye diseases, ophthalmologists should know the basic clinical and recently rapidly developing genetic characteristics of these diseases in order to properly approach the diagnosis and treatment and to provide genetic counseling. In this paper, posterior segment eye diseases of genetic origin are reviewed, and retinoblastoma, mitochondrial diseases, retinal dysplasia, retinitis pigmentosa, choroideremia, gyrate atrophy, Alström disease, ocular albinism, optic nerve hypoplasia, anophthalmia/microphthalmia and Leber’s congenital amaurosis are covered. (Turk J Ophthalmol 2012; 42: 386-92

  4. A study of ophthalmologic profile of patients with glaucoma

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    E. Vasanthamurthy

    2016-05-01

    Conclusions: Prevalence of glaucoma was more in the age group of 40-49 years. Prevalence was more among males compared to females. Right side of eye was commonly affected. [Int J Res Med Sci 2016; 4(5.000: 1388-1391

  5. Avaliação epidemiológica dos pacientes vítimas de queimadura ocular pelo agente químico cal no Serviço de Oftalmologia do Hospital Universitário Evangélico de Curitiba Epidemiological assessment at the Ophthalmology Departament of the Evangelic University Hospital of Curitiba of patients victims of ocular lime burns

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    Alessandra Guerra Daros Castellano

    2002-06-01

    Full Text Available Objetivo: Avaliar o perfil epidemiológico dos pacientes vítimas de queimadura ocular pelo agente químico cal, no Serviço de Oftalmologia do Hospital Universitário Evangélico de Curitiba, enfatizando-se os casos de queimaduras oculares pela "Bomba de Cal". Métodos: Estudo prospectivo de 88 pacientes com queimadura ocular pela cal (cal sem explosão ou bomba de cal, que procuraram o serviço de Pronto Atendimento do referido hospital no período de setembro de 1999 a setembro de 2000. Resultados: Dos 88 pacientes avaliados 73 (82,95% foram vítimas de queimadura ocular pela cal no ambiente de trabalho e 15 (17,24% foram vítimas da "Bomba de Cal" (brincadeira regional. A maioria dos pacientes examinados foi do sexo masculino, com faixa etária entre 20 e 40 anos, com predomínio de queimadura ocular unilateral e grau I quando vítimas de acidente de trabalho e bilateral e grau IV quando a queimadura foi resultante da "Bomba de Cal". Conclusão: Comparando-se os grupos estudados observou-se que o grupo vítima de queimadura ocular pela "Bomba de Cal" apresentou maior agravo à saúde ocular demonstrado, neste estudo, pela bilateralidade, gravidade das lesões e idade mais precoce de acometimento dos pacientes.Purpose: The assessment of the epidemiological profile of patients victims of lime ocular burns, by the Ophthalmology Department of the Evangelic University Hospital of Curitiba, with emphasis on "Lime Bomb" burn cases. Methods: A study on 88 ocular lime burn patients (lime bomb or not, who came to the HUEC Emergency Service from September 1999 to September 2000. Results: Of 88 patients that were evaluated, 73 (82.95% had suffered ocular lime burn in their working place and 15 (17.24% had suffered it due to the `Lime Bomb" itself (local custom. Most of the patients that were examined were males, aged 20-40 years, with predominance of unilateral ocular burn and degree I in case of accident at the workplace, and bilateral and degree IV in

  6. Afecções oculares prevalentes em crianças de baixa renda atendidas em um serviço oftalmológico na cidade do Recife - PE, Brasil Prevalence of ocular disorders in poor children attending an ophthalmologic clinic in Recife - PE, Brazil

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    Raquel Costa Albuquerque

    2003-12-01

    Full Text Available OBJETIVOS: Descrever os distúrbios visuais diagnosticados em um grupo de crianças carentes, assistidas no serviço oftalmológico do Instituto Materno-Infantil de Pernambuco (IMIP. MÉTODOS: Estudo descritivo, realizado com uma amostra representativa (n=388, selecionada de forma aleatória da clientela de baixa renda na faixa etária de 0 a 15 anos, atendida no período de fevereiro a outubro de 2001 no IMIP. Os diagnósticos, estabelecidos pelos médicos oftalmologistas do serviço, foram classificados de acordo com o CID-10. RESULTADOS: Os distúrbios visuais mais detectados (63,9%, foram os transtornos dos músculos oculares, do movimento binocular, da acomodação e da refração, sendo o estrabismo e a hipermetropia os mais comuns. Seguiram-se os transtornos da conjuntiva e da pálpebra (20,0%, da coróide e da retina (5,1% e do cristalino (3,9. Transtornos da esclerótica e do humor vítreo, glaucoma congênito, cegueira e outros distúrbios foram observados em menor freqüência. CONCLUSÕES: Os distúrbios visuais são comuns nas crianças carentes, sendo os erros de refração e o estrabismo os mais observados na casuística estudada, o que justifica programas de triagem na população infantil.PURPOSE: To describe the commonest visual disorders in a group of poor children attending the Ophthalmology Clinic at the "Instituto Materno-Infantil de Pernambuco (IMIP". METHODS: Descritive study. A randomly selected sample (n=388 of children under the age of 15, from low-income families, seen at IMIP between February and October 2001. Eye disorders were classifical according to the ICD-10 by ophthalmologists in the clinic. RESULTS: Visual problems related to eye muscular disorders (binocular movement, accommodation, refraction were detected in most cases (63.9% and hyperopia and strabismus were the commonest. Disorders of the conjunctiva and eyelid were found in 20% of the cases, followed by choroid and retina (5.1% and the lens (3

  7. Comparison of methods for the measurement and statistical analysis of visual acuity in articles published in Chinese and American ophthalmological journals%中外眼科学术期刊中视力的检测和统计方法比较

    Institute of Scientific and Technical Information of China (English)

    陈浩宇; 唐仕波; 丁小燕

    2010-01-01

    目的 比较(简称C刊)和(简称A刊)上发表的临床科研论文中采用的视力检测方法和统计方法的区别.方法 收集2003-2005年C刊和A刊所有涉及视力的临床科研论文全文.记录每篇论文是否说明视力表类型、视力记录法、是否将小数或分数记录法转换为对数记录法、视力的描述性统计、推断性统计方法、是否使用图表描述视力、是否使用表格列出所有患者的视力等方面资料.计算两种期刊中各自采用的各种方法的比例,并进行比较.结果 C刊3年共刊出论著400篇,有132篇(33.0%)涉及视力;A刊共刊出论著616篇,有358篇(58.1%)涉及视力.C刊和A刊各有77.3%和50.8%的论文没有说明使用的视力表类型.C刊中91.7%的论文采用小数记录法,其中2.6%转换为对数记录法,另外有3.8%的论文直接采用对数记录法:而A刊中74.9%的论文采用分数记录法,其中29.4%转换为对数记录法,另外有14.0%的论文直接采用对数记录法.C刊中采用平均值、标准差和中位数的比例分别为8.3%、6.1%和0%,而A刊分别为31.0%、16.8%和14.0%.C刊使用t检验或方差分析的比例只有5.3%,而A刊为19.0%.C刊采用图表描述视力和用表格列出全部患者视力的比例分别为2.3%和6.8%,A刊则分别为14.2%和24.9%.结论 C刊主要是采用小数记录法,而A刊除了采用分数记录法外,也有相当部分采用对数记录法,或者将分数记录法转换为对数记录法;A刊的论文更多采用平均值、标准差、中位数、t检验、方差分析等统计学分析方法,更多使用图表描述视力和使用表格列出所有患者视力资料.%Objective To evaluate and compare the methods of measurement and statistical analysis of visual acuity (VA) in articles published in the Chinese Journal of Ophthalmology (CJO)and the American Journal of Ophthalmology (AJO). Methods The full text of articles published in CJO and AJO from 2003 to 2005 were obtained. Data

  8. 芬太尼与球后神经阻滞联合瑞芬太尼在小儿全麻眼科手术中的对比研究%A comparative study in children undergoing ophthalmologic surgery during general anesthesia:systemic fentanyl vs. retrobulbar block combined with remifentanyl

    Institute of Scientific and Technical Information of China (English)

    姜柏林; 赵红; 姚兰; 冯艺

    2016-01-01

    Objective To evaluate the influence of retrobulbar block combined with remifentanyl vs. systemic fentanyl on the hemodynamic response, stress response, inflammatory response, postoperative analgesia and perioperative adverse events in pediatric ophthalmologic surgeries during general anesthesia. Methods A total of 28 children undergoing vitreoretinal surgeries in Peking university people's hospital from Jun. 2013 to Mar. 2014 were enrolled in the study, whose age were 1-6 years. They were randomly assigned into 2 groups: retrobulbar nerve block combined with remifentanyl group (group N, n=13) and systemic fentanyl group (group F, n=15). Anesthesia was induced and maintained with propofol, and laryngeal mask airway was placed after rocuronium bromide given intravenously, following pressure control ventilation. In group N, remifentanyl was pumped continuously, and satisfying retrobulbar nerve block was achieved before surgical procedure. In group F, intravenous fentanyl was administrated intermittently. Two blood samples were collected before and after surgery to measure plasma cortisol, glucose and cytokines concentrations. The mean arterial pressure and heart rate were recorded at the time of before the induction of anesthesia (T0), after laryngeal mask airway placement (T1), beginning of surgery (T2), ending of surgery (T3), laryngeal mask airway removal (T4), leaving operating room (T5). The emergence time and time interval from cease of surgery to the laryngeal mask removal were recorded. The Pain Scales were assessed immediately after emergence from anesthesia, 2 h later and 24 h later, respectively. The adverse events during and after surgery were also recorded. Results The heart rate (per minute) in group N was significantly lower than in group F at T0, T2 and T3, respectively, (100.5±17.6)times/beat vs. (123.4±26.5)times/beat, t=-2.656, P=0.013; (85.2±14.9)times/beat vs. (119.3±26.0)times/beat, t=-4.179, P<0.001; (86.8±19.1)times/beat vs. (112.7±26

  9. Análise da viabilidade econômica da unidade móvel de um serviço de referência em oftalmologia Analysis of economic viability of a mobile eye clinic of a referral ophthalmology service

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    Luiz Henrique Soares Gonçalves de Lima

    2005-10-01

    Full Text Available OBJETIVO: Analisar a viabilidade econômica da Unidade Móvel de um Serviço de Referência terciária em Oftalmologia. MÉTODOS: Foi considerado o montante gasto com a sua compra e construção no ano 2000 e as despesas com a sua manutenção e funcionamento no ano 2001, comparando-se com a receita gerada a partir de consultas, exames complementares e cirurgias oculares do Sistema Único de Saúde no ano 2001. Para fins de análise econômica, determinou-se uma taxa de juros de 10% ao ano e um período de depreciação de 10 anos. RESULTADOS: O valor total para aquisição e montagem da Unidade Móvel do Hospital Oftalmológico de Sorocaba foi de R$ 184.140,00. O montante gasto com despesas para a sua manutenção e funcionamento durante o ano 2001 foi de R$ 28.000,00. A Unidade funcionou, em média, durante 2 dias por semana no ano 2001 e foram realizadas, nesse período, 6.492 consultas, estabelecendo-se uma receita de R$ 32.460,00. As consultas geraram exames complementares e cirurgias oculares, contabilizando-se R$ 51.540,00. Portanto, a receita obtida diretamente com as consultas, exames complementares e cirurgias durante o ano 2001 foi R$ 84.000,00, pagos pelo Sistema Único de Saúde, de acordo com valores pré-estabelecidos. A partir desses valores é possível uma análise econômica do empreendimento e esta foi feita com e sem poupança para depreciação, levando-se em consideração as despesas e as receitas. CONCLUSÃO: Além de prestar atendimento a comunidades carentes e distantes, uma Unidade Móvel pode ser fonte de renda para um Serviço de Oftalmologia.PURPOSE: To analyse the economic viability of a mobile eye clinic of a tertiary referral Ophthalmology Service. METHODS: The amount of money spent with the purchase and construction of the unit in 2000, and the expenses with its maintenance and operation in 2001 were considered, comparing these expenses with the income obtained from appointments, supplementary tests and eye

  10. Analysis of visual field changes of the temporal and occipital lobe infarction on those first visit in the Department of Ophthalmology%首诊于眼科颞枕叶脑梗死患者视野改变分析

    Institute of Scientific and Technical Information of China (English)

    刘占芬; 陈正伟; 郭金喜

    2013-01-01

    目的 探讨颞枕叶脑梗死患者的常见视野改变及其危险因素.方法 自2000年至2006年对就诊于眼科门诊的95例经CT检查确诊为颞枕叶脑梗死的患者用Octopus自动视野计进行检查并作统计分析.结果 视野改变:同侧偏盲者73例,占76.84%;同侧象限盲者13例,占13.68%;管状视野者5例,占5.26%;同侧偏盲样中心暗点者3例,占3.16%;下半盲者1例,占1.05%.患高血压病者66例,占69.47%;高血压合并糖尿病者4例,占4.21%;糖尿病者4例,占4.21%.结论 颞枕叶脑梗塞患者视野改变多为同侧性视野缺损,高血压是其最重要的独立危险因素,糖尿病也是其危险因素.%Objective To study the characteristics of the temporal and occipital lobe infarction visual field changes and its risk factors.Methods Retrospectively analyzed 95 cases treated in the Department of Ophthalmology in our hospital.The patients were diagnosed by CT screening for temporal and occipital lobe cerebral infarction with Octopus automated perimetry for inspection and statistical analysis.Results Visual field changes of homonymous hemianopia in 73 cases,accounting for 76.84%; the ipsilateral quadrantanopia in 13 cases accounting for 13.68%; tubular vision in 5 cases,accounting for 5.26%; central hemianopic scotoma in 3 cases,accounting for 3.16%; the lower half hemianopia in 1 case,accounting for 1.05%.Risk of hypertension in 66 cases,accounting for 69.47%; hypertension combined with diabetes mellitus in 4 cases,accounting for 4.21%; diabetes mellitus in 4 cases,accounting for 4.21%.Conclusions The temporo-occipital lobe infarction often resuits in homonymous hemianopic defects of visual field,hypertension is the most important independent risk factor,and diabetes mellitus is also a risk factor.

  11. Resultados de la calidad visual óptima en pacientes operados de catarata en el Instituto Cubano de Oftalmología “Ramón Pando Ferrer” 2009 Results of the optimal visual quality in patients operated on from cataract at “Ramon Pando Ferrer” Cuban Institute of Ophthalmology in 2009

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    Abel Plasencia Blanco

    2011-12-01

    aberrometric modifications (measured by the OPD Scan II Nidek in the cataract surgeries performed from January to July 2009 at the Ocular Microsurgery Department in “Ramón Pando Ferrer" Cuban Institute of Ophthalmology. Of the universe of 353 patients, 300 eyes operated from cataract from 220 selected patients were used. All the cases were surgically treated by the same surgeon who used the same technique called phacoemulsification. The variables under study were best corrected visual acuity pre and postoperative, Function of modular transfer, Strehl’s, wave front error, sensitivity on contrast test, and internal and total corneal aberrations and before and after surgery. The results were shown in charts with absolute and relative frequencies based on reliable statistical methods. Results: The best corrected visual acuity improved 4,5 lines in the Snellen’s chart. The values of function of modular transfer and the Strehl’ index increased but the wave front diminished. The internal and the total aberrations increased but the corneal aberrations did not change significantly. Conclusions: The patients included in this study obtained a quality visual in agreement physics to the opposing biological results, element that endorses the necessity to make this mensurations systematically so that the biggest visual perfection is always achieved that contributes the patient an useful social life.

  12. Manifestações oculares do paciente infectado pelo HIV atendido no Departamento de Oftalmologia da Universidade Federal de São Paulo Ocular manifestations of the HIV infected Patients at the Ophthalmology Department of São Paulo Federal University

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    K. T. F. Matos

    1999-12-01

    Full Text Available OBJETIVO: Avaliar as manifestações oculares do paciente HIV positivo. MATERIAL E MÉTODOS: É um estudo retrospectivo em 1100 pacientes ambulatoriais HIV positivo em três anos com ficha padrão e exame oftalmológico completo, atendidos no Departamento de Oftalmologia da Escola Paulista de Medicina. RESULTADOS: Dos 1100 pacientes, 869 (79% eram do sexo masculino e 231 (21% do feminino. Os fatores de risco mais importantes foram: homossexualidade masculina em 303 (27,55%, heterossexualidade em 272 (24,73%, usuários de drogas endovenosas em 168 (15,27% e causa indeterminada ou não revelada em 246 (22,36%. As queixas oculares mais freqüentes foram: 432 (39,27% pacientes com baixa da acuidade visual; 138 (12,55% com embaçamento visual; 64 (5,82% com dor ocular, 186 (16,9% com queixas inespecíficas e 235 (21,36% pacientes não apresentavam qualquer queixa. As manifestações oculares mais freqüentes foram: retinite por CMV em 246 (22,36% dos pacientes; exsudatos algodonosos em 110 (10%, blefarite em 51(4,64% e toxoplasmose ocular em 48 (4,36%. CONCLUSÃO: Houve progressão da doença entre os heterossexuais e aumento da incidência no sexo feminino nesta população estudada. Os que apresentavam queixas oculares foram a maioria. A manifestação ocular mais freqüente foi a retinite por CMV em 246 (22,36%. Encontramos 10% de exsudatos algodonosos.PURPOSE: To evaluate ocular manifestations of HIV-infected patients MATERIAL AND METHODS: A restropective study of 1,100 HIV positive out patients in 3 years with a standard complete ophthalmological exam. RESULTS: Eigth hundred and sixty nine (79% of the 1,100 patients studied were male and 231 (21% female. The most important risk factors were: male homossexuality in 303 cases (27.55%, heterossexuality in 272 (24.73%, endovenous drugs use in 168 (15.27%, and unknown cause in 246 (26.36%. Related to ocular complains, we found 432 (39.27% patients with decreased visual acuity, 138 (12.55% with visual

  13. Facoemulsificación mediante técnica de Tilt and Tumble. Instituto Cubano de Oftalmología “Ramón Pando Ferrer” 2002-2005 Phacoemulsification using Tilt & Tumble´s technique in “Ramón Pando Ferrer” Cuban Institute of Ophthalmology, 2002-2005

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    Juan Raúl Hernández Silva

    2006-06-01

    Full Text Available La cirugía refractiva de catarata ha llegado convertirse en una filosofía bien definida y aceptada por los cirujanos de segmento anterior. Esto significa que el objetivo a lograr debe planificarse cuidadosamente, y que la técnica quirúrgica realizada debe ser precisa. La principal motivación para la realización de este trabajo, es estudiar los resultados de la técnica de Tilt and Tumble en la cirugía de extracción de catarata por facoemulsificación y su comportamiento en nuestro medio. Se realizó un estudio descriptivo, prospectivo de corte transversal, cuyo universo estuvo constituido por 272 pacientes (ojos del Centro de Microcirugía Ocular (CMO del Instituto Cubano de Oftalmología “Ramón Pando Ferrer” seleccionados mediante un muestreo simple aleatorio, con una edad promedio de 61 años. La mayoría de ellos presentaron dureza del cristalino y tiempo promedio de ultrasonido bajo. La agudeza visual preoperatoria y posoperatoria promedio con corrección mejoró significativamente en 5 líneas de la cartilla de Snellen. El astigmatismo inducido por la cirugía fue bajo. Finalmente se analizaron las complicaciones y se detallaron los accidentes que ocurrieron durante el acto quirúrgico, y se observó que la ruptura de cápsula posterior y la salida de vítreo fueron los eventos los más frecuentesRefractive surgery of cataract has become a well-defined and widely-accepted technique by surgeons in charge of the anterior segment. This means that the objectives to be achieved should be carefully planned and that the surgical technique should be accurate. The main purpose of this paper was to study the results of Tilt & Tumble´s technique in cataract removal surgery using phacoemulsification and its performance in our context. A prospective cross-sectional descriptive study was conducted on 272 patients (eyes seen at the Ocular Microsurgery Center of “Ramón Pando Ferrer” Cuban Institute of Ophthalmology, who were selected by

  14. Facoemulsificación en casos especiales: Instituto Cubano de Oftalmología “Ramón Pando Ferrer”, 2002-2005 Phacoemulsification applied to special cases in “Ramon Pando Ferrer” Cuban Institute of Ophthalmology, 2002-2005

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    Juan Raúl Hernández Silva

    2006-06-01

    phacoemulsification. Our main reason for this paper is to study the results achieved in special cases and their performance in our context. The special cases cover severe myopia and hypermetrophy, refractive postsurgery, small pupilla, uveitis, congenital cataract, subluxed cataract, trauma, hypermature cataract, vitrectomy-combined cataract, penetrating keratoplasty and glaucoma. In all these cases, phacoemulsification techniques has been upgraded and auxiliary instruments have been introduced to contribute to surgical success and to reduce to minimum eye surgery complications that are potentially complex in the preoperative phase. Among the most frequent causes of small pupillae are the occurence of miotic agents, exfoliative syndrome, Horner´s syndrome secondary to trauma and inflammation. A prospective cross-sectional descriptive study was undertaken in a universe of 39 patients (eyes seen at the Ocular Microsurgery Center of “Ramón Pando Ferrer” Cuban Institute of Ophthalmology. They had been selected through a simple randomized sampling and their average age was 61 years. The majority of patients presented with hard crystalline lens and low average time of ultrasound application. Average preoperative and postoperative visual acuity with correction significantly improved by 4 lines of Snellen´s chart. Surgically-induced astigmatism was low. Finally, the complications were analyzed, the accidents occured during surgery were detailed and the rupture of posterior capsula and vitreous detachment were the most frequent events found

  15. Resultados del implante múltiple de lentes intraoculares en la cirugía de catarata en el Instituto Cubano de Oftalmología "Ramón Pando Ferrer" Results of the multiple intraocular lenses implantation in the cataract surgery performed at "Ramón Pando Ferrer" Cuban Institute of Ophthalmology

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    Eric Montero Díaz

    2010-06-01

    Full Text Available OBJETIVO: Valorar los resultados visuales de los pacientes operados con la técnica de piggy back o implantes múltiples de lentes intraoculares. MÉTODOS: Se realizó un estudio descriptivo retrospectivo de corte transversal en el que se tomaron 32 ojos de 30 pacientes del universo operado de catarata, con la técnica antes descrita, en el Instituto Cubano de Oftalmología "Ramón Pando Ferrer", en el período comprendido entre enero de 2000 hasta diciembre de 2006. Fueron evaluadas algunas variables demográficas, como edad y sexo, así como agudeza visual y refracción preoperatorio y posoperatoria con cristales y sin ellos. Reportamos las complicaciones transquirúrgicas y posquirúrgicas asociadas a las diferentes técnicas quirúrgicas empleadas para la extracción del cristalino. RESULTADOS: La edad promedio obtenida fue mayor de 50 años, y predominó el sexo femenino. Parte de los pacientes tuvieron una agudeza visual corregida superior a 20/40. La complicación más frecuente fue la opacidad de la cápsula posterior y solo en la tercera parte de los pacientes se obtuvo una buena corrección refractiva. CONCLUSIONES: La técnica de piggy back permitió la recuperación de cuatro líneas en la cartilla de Snellen en la agudeza visual corregida, mientras que en la agudeza visual sin corrección solo aumentó en dos líneas. Se encontró igual número de pacientes hipocorregidos y bien corregidos.OBJECTIVE: To asses the visual results of patients operated on by piggy back technique or multiple implantation of intraocular lenses METHODS: A retrospective cross-sectional descriptive study was conducted in 32 eyes from 30 patients operated on from cataract, using the above-mentioned technique, at "Ramon Pando Ferrer" Cuban Institute of Ophthalmology in the period January 2000 through December 2006. Some demographic variables as age and sex as well as visual acuity and preoperative and postoperative refraction with/without lenses were evaluated

  16. 丙泊酚联合瑞芬太尼喉罩通气与氯胺酮麻醉在小儿眼科手术的比较%COMPARISON OF PROPOFOL COMBINED WITH REMIFENTANIL AND LARYNGEAL MASK ANES-THESIA AND KETAMINE INTRAVENOUS ANESTHESIA IN CHILDREN OPHTHALMOLOGIC SURGER-Y

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    郑育娟; 敖利; 史金鳞; 白耀武; 钱金洪; 高秀江

    2014-01-01

    Objective To explore the feasibility and safety of propofol combined with remifentanil with la-ryngeal mask in pediatric ophthalmology surgery by comparison of propofol combined with remifentanil and laryngeal mask anesthesia and ketamine intravenous anesthesia .Methods Sixty-six children ,aged 1 to 8 , ASA Ⅰ toⅡ ,scheduled for ophthalmology surgery were randomly divided into two groups :remifentanil group (group A) and ketamine group (group B) .The children in group A were given propofol 3mg /kg and remifentanil 2μg /kg by intravenous injection slowly ,then inserted the laryngeal mask and assisted mechanical ventilation after body movement disappeared and jaw slack ,the anesthesia was maintained by remifentanil 0 .25~0 .3μg /(kg・min)and propofol 810mg /(kg・min) .The children in group B were giv-en intramuscular injection of ketamine 6 -8mg /kg and intravenous injection of propofol 2 -3 mg /kg , and the spontaneous breathing were kept and given oxygen mask 2L /min .The anesthesia was maintained by propofol 8-10mg /(kg・min)and intermittent intravenous injection of ketamine 0 .5 -1 mg /kg ac-cording to surgery requires .The changes of HR (heart rate) ,MAP (mean arterial pressure) ,SpO2 were recorded and analyzed at the time point before anesthesia (T1 ) ,after anesthesia 5 min (T2 ) ,at the start of surgery (T3 ) ,after surgery began 10 min (T4 ) and at the end of surgery (T5 ) in two groups .And the op-erative time ,the length of time of children Aldrete score to 9 points ,the stay time of anesthesia recovery room (PACU) and perioperative adverse reactions were also recorded and analyzed .Results The changes of HR and MAP in group A during surgery were significantly better than that in group B (P0 .05) .Compared with group B ,the length of time of children Aldrete score to 9 points and the stay time of PACU in group A were significantly shortened (P<0 .05) .In the incidence of postoperative agitation ,nausea and vomi-ting ,children in group A was

  17. Técnica de extracción extracapsular del cristalino por túnel córneo-escleral en el Instituto Cubano de Oftalmología “Ramón Pando Ferrer”, años 1999-2006 Use of extracapsular extraction of crystalline through corneal scleral tunnel technique at “Ramón Pando Ferrer” Ophthalmology Institute, 1999-2006

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    Juan Raúl Hernández Silva

    2006-06-01

    Full Text Available El vertiginoso desarrollo de la oftalmología en Cuba en los últimos años ha motivado que se introduzcan nuevas técnicas quirúrgicas para el tratamiento de la catarata, algunas de ellas modificadas a partir de otras que buscan perfeccionar sus resultados introduciendo conceptos que las optimizan; ya se han publicado valoraciones de diferentes resultados preliminares. Con la realización de este trabajo, se pretende determinar los resultados de la técnica de extracción extracapsular del cristalino (EECC por túnel córneo-escleral modificada por el doctor Hernández Silva en el Centro de Microcirugía Ocular (CMO. Se realizó un estudio descriptivo, prospectivo de corte transversal, cuyo universo estuvo constituido por todos los pacientes (ojos con diagnóstico de catarata presenil y senil que recibieron tratamiento quirúrgico con la técnica EECC por túnel córneoescleral en el CMO desde enero de 1999 hasta enero de 2006. Se seleccionó una muestra mediante un muestreo simple aleatorio de 2 537 pacientes. La mayoría de los pacientes estudiados presentaban más de 60 años de edad. La agudeza visual con corrección alcanzada mejoró como promedio en 5 líneas en la cartilla de Snellen, con un astigmatismo inducido promedio de 1,02 D. La pérdida celular endotelial fue de 8,3 %. Se presentaron pocas complicaciones; fueron las más frecuentes la ruptura de cápsula posterior y la salida de vítreoThe accelerated development of ophthalmology in Cuba in the last few years has led to the introduction of new surgical ocular techniques to treat cataract; some of them have been adapted from others, in order to improve their results by introducing optimizing concepts. A number of assessments on various preliminary outcomes have already been published. This paper was intended to determine the results achieved by Dr Hernández Silva-modified extracapsular extraction of crystalline through corneal scleral tunnel technique, which is performed at the

  18. Importance of the stem cell microenvironment for ophthalmological cell-based therapy.

    Science.gov (United States)

    Wan, Peng-Xia; Wang, Bo-Wen; Wang, Zhi-Chong

    2015-03-26

    Cell therapy is a promising treatment for diseases that are caused by cell degeneration or death. The cells for clinical transplantation are usually obtained by culturing healthy allogeneic or exogenous tissue in vitro. However, for diseases of the eye, obtaining the adequate number of cells for clinical transplantation is difficult due to the small size of tissue donors and the frequent needs of long-term amplification of cells in vitro, which results in low cell viability after transplantation. In addition, the transplanted cells often develop fibrosis or degrade and have very low survival. Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPS) are also promising candidates for cell therapy. Unfortunately, the differentiation of ESCs can bring immune rejection, tumorigenicity and undesired differentiated cells, limiting its clinical application. Although iPS cells can avoid the risk of immune rejection caused by ES cell differentiation post-transplantation, the low conversion rate, the risk of tumor formation and the potentially unpredictable biological changes that could occur through genetic manipulation hinder its clinical application. Thus, the desired clinical effect of cell therapy is impaired by these factors. Recent research findings recognize that the reason for low survival of the implanted cells not only depends on the seeded cells, but also on the cell microenvironment, which determines the cell survival, proliferation and even reverse differentiation. When used for cell therapy, the transplanted cells need a specific three-dimensional structure to anchor and specific extra cellular matrix components in addition to relevant cytokine signaling to transfer the required information to support their growth. These structures present in the matrix in which the stem cells reside are known as the stem cell microenvironment. The microenvironment interaction with the stem cells provides the necessary homeostasis for cell maintenance and growth. A large number of studies suggest that to explore how to reconstruct the stem cell microenvironment and strengthen its combination with the transplanted cells are key steps to successful cell therapy. In this review, we will describe the interactions of the stem cell microenvironment with the stem cells, discuss the importance of the stem cell microenvironment for cell-based therapy in ocular diseases, and introduce the progress of stem cell-based therapy for ocular diseases.

  19. Medical terminology across the centuries: distinctive features of a chronological study in the field of ophthalmology

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    María José Esteve Ramos

    2006-10-01

    Full Text Available This article deals with the comparison of the lexical features of two texts from a diachronic point of view. Interest in lexical comparison arises from the fact that the two texts belong to a specialised field within medicine –ophthalmology– and both can be considered of the same genre. The linguistic analysis focuses on morphological and etymological aspects, based on previous studies with a historical perspective in the field of medicine (Norri, 1992. As a result of the study, different implications concerning the use of words from the Germanic native stock or from other sources, together with the different social and scientific changes, are shown in this article.

  20. Combination of a Laser and Stem Cells in Posterior Eye Ophthalmology

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    Lukashev, Alexei; Baranov, Eugene; Gavrilova, Natalia; Saburina, Irina; Revischin, Alexander; Tornambe, Paul

    2010-05-01

    Investigation of combined application of different type of cells, delivery methods with laser irradiation of retina on an animal model in vivo(rabbit eye) was the purpose of the study. An argon at 514nm and a dye laser at 577nm with were used to provide a controlled damage on the rabbit retina. Two type of human progenitor stem cells(hPSC) were tested: Mesenchymal and Neural. Four cell delivery methods were compared: Retrobulbar, Introvitreous, Subconjuctival and Suprachoroidal injections. Electroretinography(ERG) was used as a diagnostics of retina functionality. Selective immunohystochemical analysis was performed to assess cells migration and viability. Controlled laser damage on retina provides strong attracting signal for stem cells. Application of laser light enhances results of stem cells injection in posterior eye and may have benefits for treatment of different types of retinopathy and macular degeneration.

  1. Knowledge discovery in ophthalmology: analysis of wet form of age-related macular degeneration treatment outcomes

    Science.gov (United States)

    Ulińska, Magdalena; Tataj, Emanuel; Mulawka, Jan J.; Szaflik, Jerzy

    2009-06-01

    Age-related Macular Degeneration (AMD), according to epidemiological data, is a main reason of social blindness among elderly people in developed countries. There are two forms of AMD: dry and wet. The first one is of good prognosis with low possibility of serious visual deterioration, while the second one usually leads to quick and severe visual impairment. The aim of our investigations is to analyse results of so called real-life treatment of wet AMD. We analysed outcomes of our patients treated with intravitreal injections of anti-VEGF drugs: Lucentis (61 patients) and Avastin (78 patients). We analysed changes in visual acuity (functional effect) and central retinal thickness (anatomic effect). Both drugs occurred to be efficient in treatment of wet form of AMD, however results were more satisfying in patients with better baseline visual acuity. In our approach we used R environment - an integrated suite of software facilities for data analysis and graphics.

  2. Understanding the Neuro-ophthalmology of Head Trauma: A Review of the Current Literature.

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    Samra, Khawla Abu

    2014-01-01

    Head trauma is a major medical, social, economic, national, and public health priority issue in the United States. In severe head trauma, the overwhelming clinical manifestations are so compelling that damage to the visual system is most likely to be ignored. Both the afferent and efferent visual systems are susceptible to injury after head trauma, and physicians should be aware of the visual system and perform a thorough neuro-ophthalmic evaluation in patients presenting with head trauma.Most of the data available on neuro-ophthalmic complications of head trauma including cortical blindness, Horner's syndrome, traumatic internuclear ophthalmoplegia, and ocular motor palsy, comes from case reports highlighting the need for future studies to better understand these complications.This review summarizes some of the most important neuro-ophthalmic complications of head trauma including cortical blindness, Horner's syndrome, traumatic internuclear ophthalmoplegia, and ocular motor palsy. Search of the peer-reviewed literature was conducted using MEDLINE, Cumulative Index to Nursing and Allied Health Literature, Cochrane Library, Global Health, and MD Consult.

  3. An analysis of ophthalmology trainees' perceptions of feedback for cataract surgery training

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    Saedon H

    2013-12-01

    Full Text Available Habiba Saedon Birmingham Midland Eye Centre, Birmingham, West Midlands, UK Objectives: To determine whether feedback for cataract surgery is perceived to be given to trainee ophthalmologists, the way in which any feedback is given, and what the trainee perceives to be the effect of feedback on their performance. Design: Cross-sectional qualitative study. Participants: Twelve trainee ophthalmologists at various levels of specialty training in the UK. Methods: Semi-structured interviews were conducted via telephone or face to face. Interviews were transcribed and underwent thematic analysis using a qualitative software data package. Main outcome measures: The importance of feedback to the trainee and methods to improve the giving of feedback. Results: Feedback was thought to be a useful tool for improving performance in cataract surgery by all participants. Emergent themes were the importance of specificity of feedback and having confidence in the supervisor. Participants suggested ways that the feedback given can be improved upon. An insight was gained into how the feedback has an effect on their performance. Conclusion: This study showed that trainees perceive the feedback they receive to be of high quality. Feedback enables the trainees to self-reflect and improve their surgical techniques. Keywords: postgraduate training, education, phacoemulsification, microsurgical skills, cognitive learning, reflection

  4. Ophthalmologic Psychophysical Tests Support OCT Findings in Mild Alzheimer’s Disease

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    Elena Salobrar-Garcia

    2015-01-01

    Full Text Available Purpose. To analyze in mild Alzheimer’s disease (MAD patients, GDS-4 (Reisberg Scale, whether or not some psychophysical tests (PTs support OCT macular findings in the same group of MAD patients reported previously. Methods. Twenty-three MAD patients and 28 age-matched control subjects with mean Mini Mental State Examination of 23.3 and 28.2, respectively, with no ocular disease or systemic disorders affecting vision were included. Best-corrected visual acuity (VA, contrast sensitivity (CS (3, 6, 12, and 18 cpds, color perception (CP, and perception digital test (PDT were tested in one eye of each patient. Results. In comparison with the controls, MAD patients presented (i a significant decrease in VA, PDT, and CS for all spatial frequencies analyzed, especially the higher ones, and (ii a significant increase in unspecific errors on the blue axis (P<0.05 in all instances. In MAD patients, a wide aROC curve was plotted in all PTs. Conclusions. In MAD, CS, VA, and the tritan axis in CP were impaired. The PTs with the greatest predictive value are the higher spatial frequencies in CS and tritan unspecific errors in CP. PT abnormalities are consistent with the structural findings reported in the same MAD patients using OCT.

  5. Light through the dark ages: The Arabist contribution to Western ophthalmology

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    Imran Haq

    2012-01-01

    Full Text Available Europe in the Middle Ages had descended into a dark period, and none more so than in the field of medicine. The rich heritage of the pagan Greeks had largely been ignored or forgotten by medieval Europe, and instead it was the early Arabist world that embraced and developed the Hellenistic medical teachings, emerging not only as guardians of the classical learning still existent, but also as pioneers and innovators, restricted only by the development in the associated fields. The Kahhal (, or Oculist or Eye Specialist, had a privileged place in royal households, especially during the Abbasid period, in contrast to the time of Galen, whose writings referred to ophthalmologists in a rather derogatory manner. This elevated standing in the medical profession allowed Arabist scholars to cultivate remarkably erudite techniques and exceptional texts, which were used until very recently.

  6. Hipnoanestesia en cirugía oftalmológica Hypnoanesthesia in ophthalmological surgery

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    Juana María Maqueira Roque

    2001-06-01

    Full Text Available Se informa de un paciente de 51 años de edad, obeso e hipertenso, que sufrió traumatismo con un pedazo de hueso en su ojo derecho, presentando herida perforante córneoescleral, hernia de iris y catarata traumática parcial. En el momento del acto quirúrgico sufre grave complicación anestésica con paro respiratorio por la imposibilidad de realizar intubación endotraqueal al presentar un cuello extremadamente corto de tipo constitucional y además crisis hipertensiva. Recuperado el paciente y solo bajo los efectos de la sedación administrativa, se logra reponer el iris herniado y realizar la sutura. Posteriormente, al cabo de varios días de evolución, comienza a presentar aplanamiento de la cámara anterior, catarata intumescente e hipertensión ocular. Se decidió el uso de la hipnoanestesia por el alto riesgo quirúrgico del paciente. Se realizó extracción extracapsular del cristalino, lavado con aspiración de restos capsulares y sutura sin accidentes transoperatorios. Mantuvo su presión arterial normal. No se utilizó ningún tipo de anestésico ni sedante. Al despertar del sueño hipnótico el paciente negó haber sentido dolor, refirió sentirse bien y con sensación de bienestar. El posoperatorio transcurrió sin dificultades. El alta se produjo a las 72 h. En la actualidad su presión intraocular y arterial se mantienen normales, se encuentra pendiente de láser de una tenue membrana pupilar ciclítica.The case of a 51-year-old obese and hypertensive man, who suffered a trauma with a piece of bone in his right eye that produced a corneoscleral stab wound, hernia of the iris and traumatic partial cataract was reported. During the operation he had a severe anesthetic complication with respiratory arrest due to the impossibility of performing endotracheal intubation, since the patient had an extremely short neck of constitutional type and a hypertensive crisis, too. Once the patient recovered and only under the effects of sedation, it was possible to replace the herniated iris and to suture. After some days of evolution, he began to present flattening of the anterior chamber, intumescent cataract and ocular hypertension. It was decided to use hipnoanesthesia because of the high surgical risk of the patient. Extracapsular extraction of the crystalline lens, lavage with aspiration of capsular remains and suture were made with no transoperative accidents. The patient maintained a normal arterial pressure. No anesthetics or sedatives were used. On waking up from the hypnotic sleep the patient denied having had any pain. He also said that he felt fine and that he had a sensation of well-being. No difficulties were observed during the postoperative period. He was discharged at 72 hours. At present, his intraocular and arterial pressures are normal and he is in the process of being treated with laser due to a thin pupillary cyclitic membrane.

  7. Nomenclatura anatômica em oftalmologia Anatomical nomenclature in ophthalmology

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    Ricardo Lamy

    2008-06-01

    Full Text Available Os objetivos deste estudo são: informar os oftalmologistas sobre as diferenças existentes entre as listas em língua inglesa e portuguesa de termos equivalentes para as estruturas do olho, ambas aprovadas pela Comissão Federativa Internacional de Terminologia Anatômica; apresentar os termos anatômicos incluídos na lista de descritores publicada pela Biblioteca Nacional de Medicina Norte-Americana e traduzida pela Biblioteca Regional de Medicina (BIREME; para propor uma lista em português de termos de uso comum pelos oftalmologistas.The purposes of this article are: to inform ophthalmologists about the differences between the English and Portuguese list of equivalent terms for eye structures, approved by the Federative International Committee on Anatomical Terminology; to present the anatomical terms included in the list of medical subject headings published by the United States National Library of Medicine and translated by the Regional Library of Medicine (BIREME; propose a list of Portuguese terms of common usage by ophthalmologists.

  8. Image analysis for ophthalmological diagnosis image processing of Corvis ST images using Matlab

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    Koprowski, Robert

    2016-01-01

    This monograph focuses on the use of analysis and processing methods for images from the Corvis® ST tonometer. The presented analysis is associated with the quantitative, repeatable and fully automatic evaluation of the response of the eye, eyeball and cornea to an air-puff. All the described algorithms were practically implemented in MATLAB®. The monograph also describes and provides the full source code designed to perform the discussed calculations. As a result, this monograph is intended for scientists, graduate students and students of computer science and bioengineering as well as doctors wishing to expand their knowledge of modern diagnostic methods assisted by various image analysis and processing methods.

  9. Focus Groups in Elderly Ophthalmologic Patients: Setting the Stage for Quantitative Preference Elicitation.

    Science.gov (United States)

    Danner, Marion; Vennedey, Vera; Hiligsmann, Mickaël; Fauser, Sascha; Stock, Stephanie

    2016-02-01

    Patients suffering from age-related macular degeneration (AMD) are rarely actively involved in decision-making, despite facing preference-sensitive treatment decisions. This paper presents a qualitative study to prepare quantitative preference elicitation in AMD patients. The aims of this study were (1) to gain familiarity with and learn about the special requirements of the AMD patient population for quantitative data collection; and (2) to select/refine patient-relevant treatment attributes and levels, and gain insights into preference structures. Semi-structured focus group interviews were performed. An interview guide including preselected categories in the form of seven potentially patient-relevant treatment attributes was followed. To identify the most patient-relevant treatment attributes, a ranking exercise was performed. Deductive content analyses were done by two independent reviewers for each attribute to derive subcategories (potential levels of attributes) and depict preference trends. The focus group interviews included 21 patients. The interviews revealed that quantitative preference surveys in this population will have to be interviewer assisted to make the survey feasible for patients. The five most patient-relevant attributes were the effect on visual function [ranking score (RS): 139], injection frequency (RS: 101), approval status (RS: 83), side effects (RS: 79), and monitoring frequency (RS: 76). Attribute and level refinement was based on patients' statements. Preference trends and dependencies between attributes informed the quantitative instrument design. This study suggests that qualitative research is a very helpful step to prepare the design and administration of quantitative preference elicitation instruments. It especially facilitated familiarization with the target population and its preferences, and it supported attribute/level refinement.

  10. [Psychopathology and neuro-ophthalmology in meningioma of the olfactory groove].

    Science.gov (United States)

    Lange, E; Bräunig, K P; Fötzsch, R

    1982-01-01

    In 14 patients with a surgically nad histopathologically verified meningioma of the olfactory nerve groove (OGM) (12 women, 2 men), clinical findings and diagnosis were analysed, especially with respect to neuropathology and psychopathology. The apodictic theorem that an OGM leads to a Foster-Kennedy syndrome as well as to a psychopathological orbital brain syndrome cannot be maintained. The Foster-Kennedy syndrome does not occur in a characteristically high incidence, and psychopathologically an orbital brain syndrome can only be diagnosed in case of an anterior location of the OGM. The more the OGM shows starting point or growth development to or from the anterior chiasmal angle, the more is resembles that psychopathological syndrome that we have found and described for the meningioma of the Tuberculus sellae.

  11. Histologic Features of Conjunctival Melanoma Predictive of Metastasis and Death (An American Ophthalmological Thesis)

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    Esmaeli, Bita; Roberts, Dianna; Ross, Merrick; Fellman, Melissa; Cruz, Hilda; Kim, Stella K.; Prieto, Victor G.

    2012-01-01

    Purpose: In conjunctival melanoma, tumor thickness and nonlimbal location are associated with poor prognosis. However, other established high-risk features for cutaneous melanoma, including ulceration, mitotic figures, epithelioid cell type, and lymphovascular invasion, have not previously been studied extensively for their prognostic value in conjunctival melanoma. We examined the hypothesis that these features also predict regional nodal metastasis and death in conjunctival melanoma. Methods: The medical records of 44 of 46 consecutive conjunctival melanoma patients treated between June 2003 and December 2009 were retrospectively reviewed; tumor tissue was not available for the two excluded patients. Demographic and clinicopathologic features, including tumor location, tumor thickness, ulceration, mitotic rate, histology, lymphovascular invasion, and microsatellitosis, were reviewed. Outcome measures included regional nodal metastasis, distant metastasis, and death. Results: Twenty-six women and 18 men had a median age of 62 years. Regional nodal metastasis occurred in 7 patients (16%) and distant metastasis in 9 (20%). Median follow-up was 40 months. At last follow-up, 10 patients (23%) had died of disease. Tumor thickness >2.0 mm, ulceration, and mitotic figure >1/mm2 predicted regional nodal metastasis and death from disease. In addition to these three histologic features, vascular invasion, epithelioid cell type, and microsatellitosis significantly predicted death from disease. Tumor location (bulbar vs nonbulbar) was not correlated with regional nodal metastasis or death. Conclusions: In conjunctival melanoma, as in cutaneous melanoma, thicker tumor, ulceration, and higher mitotic rate are correlated with regional nodal metastasis. In addition, lymphovascular invasion, epithelioid cell type, and microsatellitosis are correlated with melanoma-related death. PMID:23818735

  12. Histopathologic Analysis of Palpebral Conjunctiva in Thyroid-Related Orbitopathy (An American Ophthalmological Society Thesis)

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    Kikkawa, Don O.

    2010-01-01

    Purpose: To examine the histopathology of palpebral conjunctiva in patients with thyroid-related orbitopathy. Based on previously published anecdotes, the hypothesis is that conjunctiva shows increased inflammation and fibrosis. Methods: This was a comparative case series. Superior palpebral conjunctiva was examined from two groups. The study group consisted of 20 patients undergoing thyroid-related upper eyelid retraction surgery. The control group consisted of 18 patients undergoing ptosis repair. Specimens were processed and stained using hematoxylin and eosin and trichrome. Histopathologic grading was performed using light microscopy. Main outcome measures were degree of inflammation and fibrosis, mast cell infiltration, and fibroblast count. Results: The two groups did not differ with regard to age or gender. Mean degree of inflammation was 1.4 (95% CI: 0.9, 1.9) for the control group and 1.7 (95% CI: 1.3, 2.1) for the study group. Relative intensity of blue from trichrome staining mean was 134.3 (95% CI: 130.3, 138.3) for the control group and 138.6 (95% CI: 133.7, 143.6) for the study group. The Mann-Whitney test showed no difference between groups in inflammation (P=.17), relative blue intensity (P=.11), degree of mast cell infiltration (P=.61), and fibroblast count (P=.45). Point estimates show a trend toward greater inflammation in the study group. Conclusions: While there is a trend toward higher inflammation in the study group, the superior palpebral conjunctiva of patients with thyroid-related orbitopathy is largely spared from autoimmune changes. This has implications in surgical approaches to eyelid retraction repair. PMID:21212848

  13. The Artificial Silicon Retina in Retinitis Pigmentosa Patients (An American Ophthalmological Association Thesis)

    Science.gov (United States)

    Chow, Alan Y.; Bittner, Ava K.; Pardue, Machelle T.

    2010-01-01

    Purpose: In a published pilot study, a light-activated microphotodiode-array chip, the artificial silicon retina (ASR), was implanted subretinally in 6 retinitis pigmentosa (RP) patients for up to 18 months. The ASR electrically induced retinal neurotrophic rescue of visual acuity, contrast, and color perception and raised several questions: (1) Would neurotrophic effects develop and persist in additionally implanted RP patients? (2) Could vision in these patients be reliably assessed? (3) Would the ASR be tolerated and function for extended periods? Methods: Four additional RP patients were implanted and observed along with the 6 pilot patients. Of the 10 patients, 6 had vision levels that allowed for more standardized testing and were followed up for 7+ years utilizing ETDRS charts and a 4-alternative forced choice (AFC) Chow grating acuity test (CGAT). A 10-AFC Chow color test (CCT) extended the range of color vision testing. Histologic examination of the eyes of one patient, who died of an unrelated event, was performed. Results: The ASR was well tolerated, and improvement and/or slowing of vision loss occurred in all 6 patients. CGAT extended low vision acuity testing by logMAR 0.6. CCT expanded the range of color vision testing and correlated well with PV-16 (r = 0.77). An ASR recovered from a patient 5 years after implantation showed minor disruption and excellent electrical function. Conclusion: ASR-implanted RP patients experienced prolonged neurotrophic rescue of vision. CGAT and CCT extended the range of acuity and color vision testing in low vision patients. ASR implantation may improve and prolong vision in RP patients. PMID:21212852

  14. A Handheld Open-Field Infant Keratometer (An American Ophthalmological Society Thesis)

    Science.gov (United States)

    Miller, Joseph M.

    2010-01-01

    Purpose: To design and evaluate a new infant keratometer that incorporates an unobstructed view of the infant with both eyes (open-field design). Methods: The design of the open-field infant keratometer is presented, and details of its construction are given. The design incorporates a single-ring keratoscope for measurement of corneal astigmatism over a 4-mm region of the cornea and includes a rectangular grid target concentric within the ring to allow for the study of higher-order aberrations of the eye. In order to calibrate the lens and imaging system, a novel telecentric test object was constructed and used. The system was bench calibrated against steel ball bearings of known dimensions and evaluated for accuracy while being used in handheld mode in a group of 16 adult cooperative subjects. It was then evaluated for testability in a group of 10 infants and toddlers. Results: Results indicate that while the device achieved the goal of creating an open-field instrument containing a single-ring keratoscope with a concentric grid array for the study of higher-order aberrations, additional work is required to establish better control of the vertex distance. Conclusion: The handheld open-field infant keratometer demonstrates testability suitable for the study of infant corneal astigmatism. Use of collimated light sources in future iterations of the design must be incorporated in order to achieve the accuracy required for clinical investigation. PMID:21212850

  15. Cosmetic Outcome of Posterior Approach Ptosis Surgery (An American Ophthalmological Society Thesis)

    Science.gov (United States)

    Goldberg, Robert A.; Lew, Helen

    2011-01-01

    Purpose To test the hypothesis that posterior approach ptosis surgery, with or without blepharoplasty, can improve the cosmetic appearance of the eyelid. Methods In a retrospective, observational, consecutive case cohort study, 261 patients who had posterior approach upper eyelid ptosis surgery with or without concurrent blepharoplasty performed by one surgeon, between 1997 and 2009, were reviewed. Patients were included if they had symmetric eyelid position within 1.5 mm at 3 months after surgery. Outcome measures were subjective grading of eyelid margin contour, millimeters of tarsal platform show (TPS), and millimeters of eyebrow fat span (BFS). Paired preoperative and postoperative standardized photographs were viewed in masked fashion by three experts. Results One hundred and forty patients (55 men, 85 women, mean age 70 years, range 20–93) who underwent 233 posterior approach procedures for correction of upper eyelid ptosis had postoperative eyelid symmetry within 1.5 mm. Concurrent blepharoplasty was performed in 67 cases. Eyelid contour scores were significantly improved following surgery (P=.009). Ptosis surgery, without blepharoplasty, decreased the TPS, from 6.1±2.5 mm to 4.8±2.0 mm (P<.001). Patients who underwent concurrent blepharoplasty had a statistically insignificant increase of TPS from 4.0±3.5 mm to 4.3±3.6 mm, had a decrease of BFS from 20.8±6.3 mm to 17.7±6.4 mm (P=.001), and showed similar BFS symmetry postoperatively, compared to patients who had ptosis surgery only. Conclusions Posterior approach surgery alone was often successful in controlling TPS: it shortened the TPS. Blepharoplasty combined with posterior approach ptosis surgery tended to lengthen the TPS and shorten the BFS. PMID:22253486

  16. Myocardial ischaemia following cocaine and adrenaline exposure in a child during an ophthalmological procedure.

    LENUS (Irish Health Repository)

    McGovern, E

    2015-03-01

    We report a 23-month old girl who presented with bilateral epiphora who underwent bilateral lacrimal probing and syringing, during which a cocaine adrenaline solution was used. Two hours after the procedure she developed acute pulmonary oedema secondary to myocardial ischaemia. The patient was treated with intravenous glyceryltrinitrate and milrinone infusions; cardiac enzymes and left ventricular function normalised over the subsequent 72 hours. Topical administration of cocaine and adrenaline solution may have dangerous systemic cardiac effects and should always be used judiciously.

  17. Sildenafil(Viagra) and Ophthalmology%昔多芬(伟哥)和眼科

    Institute of Scientific and Technical Information of China (English)

    Michael F.Marmor; 金红颖

    2000-01-01

    @@ 一种新的流行的壮阳剂--昔多芬(伟哥,Viagra;Pfizer Pharmaceuticals,纽约),虽然其适应证不在眼科学领域内,但仍有许多理由需要眼科医生对其药理学特点和潜在副作用有所了解.

  18. Uveal Melanoma Cell Lines: Where do they come from? (An American Ophthalmological Society Thesis).

    Science.gov (United States)

    Jager, Martine J; Magner, J Antonio Bermudez; Ksander, Bruce R; Dubovy, Sander R

    2016-08-01

    To determine whether some of the most often used uveal melanoma cell lines resemble their original tumor. Analysis of the literature, patient charts, histopathology, mutations, chromosome status, HLA type, and expression of melanocyte markers on cell lines and their primary tumors. We examined five cell lines and the primary tumors from which they were derived. Four of the five examined primary tumors were unusual: one occupied the orbit, two were recurrences after prior irradiation, and one developed in an eye with a nevus of Ota. One cell line did not contain the GNA11 mutation, but it was present in the primary tumor. Three of the primary tumors had monosomy 3 (two of these lacked BAP1 expression); however, all five cell lines showed disomy 3 and BAP1 expression. All of the cell lines had gain of 8q. Two cell lines lacked expression of melanocyte markers, although these were present in the corresponding primary tumor. All cell lines could be traced back to their original uveal melanoma. Four of the five primary tumors were unusual. Cell lines often differed from their primary tumor in chromosome status and melanocyte markers. However, their specific chromosome aberrations and capacity to continue proliferation characterize them as uveal melanoma cell lines.

  19. Ophthalmic Manifestations of Amyotrophic Lateral Sclerosis (An American Ophthalmological Society Thesis).

    Science.gov (United States)

    Volpe, Nicholas J; Simonett, Joseph; Fawzi, Amani A; Siddique, Teepu

    2015-01-01

    To determine if clinical and histopathologic findings were present in the eyes of patients with amyotrophic lateral sclerosis (ALS) and explore correlations to an animal model of ALS. Two patients with ALS were studied histopathologically as well as the retinas of ALS/dementia transgenic mice with dysfunctional ubiquilin2, UBQLN2(P497H). Clinical study 1, an observational, cross-sectional study, was performed using optical coherence tomography (OCT) to obtain and compare mean total macular thickness and average and quadrant specific peripapillary retinal nerve fiber layer (pRNFL) scans from 16 patients with ALS to controls. Correlation analysis was performed to evaluate the association with disease duration. Clinical study 2 consisted of measuring visual acuity, color vision, contrast sensitivity, and quality of life in 12 patients. Histopathologic studies demonstrated intraretinal inclusions in one patient and loss of ganglion cell axons in another. Mouse eyes had intraretinal inclusions in the inner plexiform layers. Total macular volume was thinner in patients compared to controls (P<.05), and 37.5% of patients with ALS had an average pRNFL below the 1st percentile. Total macular and pRNFL thickness correlated inversely with disease duration. Histopathologic analysis of ALS eyes and mice with the UBQLN2(P497H) mutation, as well as OCT measurements, supports involvement of the anterior visual pathway. We identified pathologies, including intraretinal deposits and axonal loss. pRNFL and total macular thinning found on OCT correlated with disease duration. A pattern of vision loss specific for ALS was not identified. This study confirms ocular involvement in patients and transgenic animals with ALS/dementia.

  20. The Palisades of Vogt in Congenital Corneal Opacification (An American Ophthalmological Society Thesis).

    Science.gov (United States)

    Nischal, Ken K; Lathrop, Kira L

    2016-08-01

    The purposes of this study are first, to determine if the palisades of Vogt (POV) are present or absent in cases of congenital corneal opacification (CCO) by using spectral domain ocular coherence tomography (SD-OCT), and second, in those cases already undergoing penetrating keratoplasty (PKP), to see whether the absence or presence of POV corresponds to re-epithelialization following transplant. This was a retrospective case review of 20 eyes (10 normal, 10 with CCO) evaluated with SD-OCT. The operator was masked to the clinician's assessment of the ocular surface. In those cases where the decision to perform PKP had already been made, the correlation between POV presence or absence and posttransplant graft epithelialization was determined. All cases were imaged without adverse event. Nine eyes showed some evidence of POV and corresponding vasculature. Eight of 10 affected eyes underwent PKP, and subsequently 7 eyes epithelialized and 2 showed some peripheral neovascularization. The one eye that showed no signs of POV was the one that failed to epithelialize. All control subjects had consistent and regular POV. Congenital corneal opacification is rare, and this study shows that at least some POV are present in the majority of cases of CCO. However, the palisades may not be entirely normal compared to age-matched controls. When there was absence of POV in a case of CCO, there was immediate and complete failure of epithelialization.

  1. Late ophthalmological complications after total body irradiation in non-human primates

    Science.gov (United States)

    Niemer-Tucker, M. M.; Sterk, C. C.; de Wolff-Rouendaal, D.; Lee, A. C.; Lett, J. T.; Cox, A.; Emmanouilidis-van der Spek, K.; Davelaar, J.; Lambooy, A. C.; Mooy, C. M.; Broerse, J. J.

    1999-01-01

    PURPOSE: To investigate the long-term effects of total body irradiation (TBI) on the incidence and time course of ocular complications. MATERIALS AND METHODS: Rhesus monkeys treated with TBI photon doses up to 8.5 Gy and proton doses up to 7.5 Gy were studied at intervals up to 25 years post-irradiation. They were compared with control groups with a similar age distribution. Cataract formation and ocular fundus lesions were scored according to a standardized protocol. Fluorescein angiography and histopathology was performed in selected animals. RESULTS: Cataract formation occurred after a latent period of 3-5 years. Significant cataract induction was observed for photon-doses of 8 and 8.5 Gy and beyond 20 years after proton irradiation. The severity of the lesions represents significant impairment of vision and would require cataract surgery if similar results occurred in human bone marrow transplant patients. Fluorescein angiography demonstrated a normal pattern of retinal vessels in 13 out of 14 animals (93%) from the irradiated group and in eight out of nine animals (89%) from the control group. No additional lesions apart from age-related degenerative changes could be demonstrated. Histological evaluation revealed no radiation-associated vasculopathy. CONCLUSIONS: Radiation alone for doses up to 8.5 Gy of photons does not carry a potential risk for fundus pathology, whereas clinically important cataract induction should be anticipated within 5 years after photon doses of 8.0 and 8.5 Gy and proton doses in excess of 2.5 Gy.

  2. Manifestaciones oftalmológicas de la enfermedad cerebrovascular Ophthalmological manifestations of cerebrovascular disease

    Directory of Open Access Journals (Sweden)

    J. Gállego

    2008-01-01

    Full Text Available El ojo constituye una diana para la enfermedad vascular. El estudio de la microcirculación retiniana constituye una oportunidad muy interesante para la valoración del riesgo vascular al conocer la relación existente entre los cambios vasculares en la retina y el riesgo de padecer un ictus. Es además una ventana excepcional para conocer mejor la fisiopatología de la microcirculación. La arteria oftálmica es la primera rama de la arteria carótida interna. La afectación ocular puede ser uni o bilateral. Los síntomas oculares o neuro-oftalmológicos son transitorios o persistentes y sus manifestaciones son muy heterogéneas abarcando alteraciones de la agudeza visual, trastornos de los campos visuales, síndromes oculomotores y manifestaciones clínicas corticales y subcorticales complejas. Su conocimiento puede resultar clave para instaurar las medidas preventivas pertinentes o establecer el correcto diagnóstico y la aproximación diagnóstica inmediata, tan importante en la atención de los procesos vasculares cerebrales.Transient or persistent loss of vision in one eye is a common and distinctive manifestation of occlusive vascular disease. Occasionally, both eyes are involved together or sequentially, with temporary or even permanent blindness. The internal carotid arteries supply blood to the organ of vision; therefore pathologies of those arteries caused by arteriosclerosis may have a direct influence on its functioning. The most common syndromes are temporary (amaurosis fugax or constant reduction of visual acuity. In fundus examination central retinal artery occlusion and branch retinal artery occlusion are the most common diagnosis, while retinal vein occlusion, anterior ischemic optic neuropathy, ocular ischemic syndrome are less common. There are many clinical ophtlamological manifestations due to vascular brain damage. Proper recognition and diagnosis of the disease may protect the patient against serious life-threatening complications such as stroke.

  3. [T. I. Eroshevskii--founder of the Sarmarsk school of ophthalmology].

    Science.gov (United States)

    Kotel'nikov, G P; Malov, V M

    2003-01-01

    June 26 is the 100 anniversary of Professor T.I. Yeroshevsky--the Hero of socialist Work, the winner of the USSR State Premium, the correspondent of the USSR Academy of Medical Sciences, the Honoured Scientist of the RSFSR, the Honoured Citizen of Kuibyshev (nowdays--Samara) and Gurkovo of the Bulgarian National Republic. His talent sa a innovator in science, a brilliant teacher, a talented clinician and one of the best organizers was shown in the full during the Samara period of his life. The All-Russia conference of ophthalmologists, two Volga region conferences on glaucoma were held in Kuibyshev. T.I. Yeroshevsky took part in the work of international ophthalmologists congresses in Leipzig and Canada, Kabul and Prague, Cairo and Bagdad, Mexico City and Sofia. All this contributed to the popularity and authority of T.I. Yeroshevsky and the unique union of the ophthalmic hospital with a faculty and problem laboratory. It was the first specialised ophthalmic complex in Russian Federation. Being a remarkable teacher, He trained more than a thousand students--the future doctors. More than 70 doctoral and candidate thesis were carried out and defended under his guidance. T.I. Yerosevsky's scientific interests were very diverse. He started his way in science from the research of transplantation of cornea and he devoted to it his doctoral thesis. The study of primary glaucoma was very significant in his research work. His clinic was one of the first in this country to introduce the photocoagulation of retina. At the beginning of the 1980s it introduced the laser surgery and therapy of various eye diseases. Kuibyshev clinic was also one of the first to master cataract cryoextraction and soon it reached the best results in the world in this direction. The regional clinic ophthalmic hospital, the faculty and problem laboratory are scientific centre of this country, it can be proved by 15 digests of scientific works issued under T.I. Yeroshevsky's edition the republic congress and all-Union ophthalmologist conferences held since 1952. This remarkable tradition is kept nowadays.

  4. Publications and Presentations of the Ophthalmology Branch, USAF School of Aerospace Medicine, 2001-2005

    Science.gov (United States)

    2006-07-01

    International Congress of Aviation and Space Medicine, Sydney, Australia, Sept 17, 2002. 23. CORNEAL TOPOGRAPHY CHANGES AFTER EXPOSURE TO HIGH +GZ Tutt R... CORNEAL TOPOGRAPHY & REFRACTIVE CHANGES AFTER EXPOSURE TO HIGH +GZ R. Tutt, and D. J. Ivan Presented at the Aerospace Medical Association 74h Annual...Scientific Meeting, San Antonio, TX 4-8 May 2003. 7. ANALYSIS OF CORNEAL TOPOGRAPHY PATTERNS IN USAF PILOT APPLICANTS M. Thornsberry, D. J. Ivan, J. M. Gooch

  5. The importance of an ophthalmologic examination in patients with juvenile idiopathic arthritis.

    Science.gov (United States)

    Rodríguez-García, Alejandro

    2015-01-01

    Uveitis occurs within the first year of arthritis onset in 73% of patients with juvenile idiopathic arthritis (JIA) considered at risk. The intraocular inflammation is characterized by an insidious onset and a silent and chronic clinical course capable of producing significant visual loss due to complications such as: cataract formation, secondary glaucoma, maculopathy and optic neuropathy. The absence of initial signs and symptoms, along with a deficient ophthalmic monitoring produce a delay in diagnosis with serious consequences. It has been estimated that 47% of JIA patients at risk for developing uveitis are legally blind (20/200 or worse) at least in one eye at the time of their first visit to the ophthalmologist. To reduce ocular complications and improve their visual outcome, it is necessary that rheumatologists refer all patients recently diagnosed (within the first month) with JIA for an ophthalmic evaluation, and maintain periodical follow-up visits based on classification and risk category of the disease.

  6. Kabuki make-up syndrome with genitourinary anomalies, ophthalmologic features and hyperpigmentation in an Egyptian child

    Directory of Open Access Journals (Sweden)

    Rabah M. Shawky

    2017-01-01

    Full Text Available We report a 3.5 year old male child, first in order of birth of healthy consanguineous Egyptian parents with typical characteristics of Kabuki make-up syndrome. The patient had microcephaly, high arched sparse eyebrows, hypertelorism, long palpebral fissures with eversion of the lateral third of the lower eyelids, bilateral ptosis, long eyelashes, blue sclera, depressed nasal bridge, broad nose with everted nares, and low set small deformed ears, thin lips, low post hair line, short neck, persistent fingertip pads, dysplastic nails, hypermobile joints, pigmented nevus on the back, lateral side of right foot and right leg and mild hypertrichosis over the lower back. Our patient had also a non-functioning left kidney, multiple chalazions in upper eyelids, enlargement of the glans penis, which were not reported previously, and moderate mental retardation.

  7. [Establishment of a quality management system in a department of ophthalmology].

    Science.gov (United States)

    Braune, S; Kohnen, T

    2009-08-01

    Establishing a quality management system in clinics gains more and more significance. Due to an increase of competition and the development in the daily routine in hospitals the implementation of such a system gets more relevance. The establishment and subsequent certification of the quality management system is described in this article as accomplished in our clinic. Various systems of quality management (ISO, EFQM, KTQ) have been considered and the ISO certification is explained. This article specifies basic structures such as the guidance team, quality management supervisor, and quality manual. With the implementation of such a system we aimed to ameliorate the procedures and routines for the sake of our patients and to improve the daily processes.

  8. Manifestaciones oftalmológicas de la enfermedad cerebrovascular Ophthalmological manifestations of cerebrovascular disease

    OpenAIRE

    2008-01-01

    El ojo constituye una diana para la enfermedad vascular. El estudio de la microcirculación retiniana constituye una oportunidad muy interesante para la valoración del riesgo vascular al conocer la relación existente entre los cambios vasculares en la retina y el riesgo de padecer un ictus. Es además una ventana excepcional para conocer mejor la fisiopatología de la microcirculación. La arteria oftálmica es la primera rama de la arteria carótida interna. La afectación ocular puede ser uni o bi...

  9. Statistical analysis of computed tomography scans in the Department of Ophthalmology

    Energy Technology Data Exchange (ETDEWEB)

    Takahashi, Shuji

    1987-05-01

    A retrospective analysis was made of computed tomography (CT) scans in 322 patients undergoing CT over a period of 4 years and 4 months. The ratio of males to females was 1.4. The peaks of number of patients were in their second and fifth decades of life. Computed tomography was positive for decreased bilateral visual acuity in 52 % (13/25, Group 1), decreased unilateral visual acuity in 52 % (13/25, Group 2), normal visual acuity associated with disturbed bilateral visual fields in 31 % (5/16, Group 3), disturbed unilateral eye movement unrelated to injury in 37 % (13/35, Group 4), injury related unilateral disturbance of eye movement in 88 % (14/16, Group 5), bilateral exophthalmus in 78 % (25/32, Group 6), and injury in 56 % (20/36, Group 7). Common underlying diseases or causes were brain tumor in Group 1, intracranial lesions and paranasal mucocele in Group 2, occipital lesions in Group 3, intraorbital and intracranial lesions in Group 4, blowout fracture in Group 5, endocrine ophthalmopathy in Group 6, and blowout fracture, optic canal fracture, and foreign body in Group 7. (Namekawa, K.).

  10. Update on Simulation-Based Surgical Training and Assessment in Ophthalmology

    DEFF Research Database (Denmark)

    Thomsen, Ann Sofia S; Subhi, Yousif; Kiilgaard, Jens Folke;

    2015-01-01

    Library, and Web of Science) and was completed on March 1, 2014. Overall, the included trials were divided into animal, cadaver, inanimate, and virtual-reality models. Risk of bias was assessed using the Cochrane Collaboration's tool. Validity evidence was evaluated using a modern validity framework...

  11. [Retrospective case analysis of ophthalmological and systemic risk factors in patients with retinal vascular occlusion].

    Science.gov (United States)

    Klatt, C; Purtskhvanidze, K; Hasselbach, H; Treumer, F; Hillenkamp, J; Roider, J

    2010-05-01

    The aim was to determine systemic risk factors for acute central retinal artery occlusion (CRAO) and central retinal vein occlusion (CRVO) and to evaluate the usefulness of systemic diagnostics in CRAO and CRVO. The study consisted of a retrospective chart review including 80 patients (CRAO 38, CRVO 42). All patients underwent systemic diagnostics including blood pressure measurement, blood cholesterol level, carotid Doppler imaging, transthoracic echocardiography (TTE), intraocular pressure measurement, glaucoma history and presence of thrombophilic factors. A systemic medical history was obtained. Systemic hypertension was found in 76.3% CRAO and 75.6% CRVO patients. Abnormal cardiac findings were detected in 61% (CRAO) and 22% (CRVO). Abnormal carotid findings were detected in 44.1% for CRAO and 9.5% for CRVO. Pathological thrombophilic factors were found in both groups for approximately 15%. TTE and carotid Doppler are important tools in the diagnosis of sources of emboli in patients with CRAO, while for CRVO abnormal findings are revealed by TTE and carotid Doppler less often. Thrombophilia should be ruled out in the absence of common risk factors, especially in younger patients and systemic hypertension should be adequately controlled.

  12. First Report of Tsukamurella Keratitis: Association between T. tyrosinosolvens and T. pulmonis and Ophthalmologic Infections▿

    Science.gov (United States)

    Woo, Patrick C. Y.; Fong, Angie H. C.; Ngan, Antonio H. Y.; Tam, Dorothy M. W.; Teng, Jade L. L.; Lau, Susanna K. P.; Yuen, Kwok-Yung

    2009-01-01

    We describe the first two cases of Tsukamurella keratitis, presented as eye pain with or without blurring of vision. One case was associated with trichiasis and the other with contact lens wear. The two isolates were identified as T. tyrosinosolvens and T. pulmonis, respectively, by phenotypic characterization and 16S rRNA sequencing. PMID:19369436

  13. First report of Tsukamurella keratitis: Association between T. tyrosinosolvens and T. pulmonis and ophthalmologic infections

    OpenAIRE

    Woo, Patrick C. Y.; Fong, Angie H. C.; Ngan, Antonio H. Y.; Tam, Dorothy M. W.; Teng, Jade L. L.; Lau, Susanna K. P.; Yuen, Kwok-yung

    2009-01-01

    We describe the first two cases of Tsukamurella keratitis, presented as eye pain with or without blurring of vision. One case was associated with trichiasis and the other with contact lens wear. The two isolates were identified as T. tyrosinosolvens and T. pulmonis, respectively, by phenotypic characterization and 16S rRNA sequencing. Copyright © 2009, American Society for Microbiology. All Rights Reserved.

  14. First report of Tsukamurella keratitis: association between T. tyrosinosolvens and T. pulmonis and ophthalmologic infections.

    Science.gov (United States)

    Woo, Patrick C Y; Fong, Angie H C; Ngan, Antonio H Y; Tam, Dorothy M W; Teng, Jade L L; Lau, Susanna K P; Yuen, Kwok-Yung

    2009-06-01

    We describe the first two cases of Tsukamurella keratitis, presented as eye pain with or without blurring of vision. One case was associated with trichiasis and the other with contact lens wear. The two isolates were identified as T. tyrosinosolvens and T. pulmonis, respectively, by phenotypic characterization and 16S rRNA sequencing.

  15. Genome engineering in ophthalmology: Application of CRISPR/Cas to the treatment of eye disease.

    Science.gov (United States)

    Hung, Sandy S C; McCaughey, Tristan; Swann, Olivia; Pébay, Alice; Hewitt, Alex W

    2016-07-01

    The Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) and CRISPR-associated protein (Cas) system has enabled an accurate and efficient means to edit the human genome. Rapid advances in this technology could results in imminent clinical application, and with favourable anatomical and immunological profiles, ophthalmic disease will be at the forefront of such work. There have been a number of breakthroughs improving the specificity and efficacy of CRISPR/Cas-mediated genome editing. Similarly, better methods to identify off-target cleavage sites have also been developed. With the impending clinical utility of CRISPR/Cas technology, complex ethical issues related to the regulation and management of the precise applications of human gene editing must be considered. This review discusses the current progress and recent breakthroughs in CRISPR/Cas-based gene engineering, and outlines some of the technical issues that must be addressed before gene correction, be it in vivo or in vitro, is integrated into ophthalmic care. We outline a clinical pipeline for CRISPR-based treatments of inherited eye diseases and provide an overview of the important ethical implications of gene editing and how these may influence the future of this technology.

  16. Cystic Fibrosis and New Trends by Ophthalmological Evaluation: A Pilot Study

    Directory of Open Access Journals (Sweden)

    Marcella Nebbioso

    2014-01-01

    Full Text Available Background. Cystic fibrosis (CF is characterized by hypoxia that affects several organic tissues. Retinal ganglion cells may suffer from the hypoxic status, and this may lead to alterations of retinal nerve fiber. Methods. Twenty-two eyes in CF patients were analyzed. A complete ocular evaluation and visual field exams of the 30 central degrees were performed using the frequency doubling technology (FDT. Forced expiratory volume in one second (FEV1%, forced vital capacity (FVC%, oxyhaemoglobin saturation (SpO2%, and hematocrit (Ht% have been calculated. FDT analyzed parameters were mean deviation (MD and pattern standard deviation (PSD. Pearson’s correlation was chosen as statistical analysis. Results. Data showed statistically significant relationship between MD and Ht% (r value −0.18; P=0.04, MD and FEV1% (r value −0.68; P=0.001, and MD and FVC% (r value −0.45; P=0.005. Moreover, there were correlations between PSD and Ht% (r value 0.29; P=0.03, PSD and SpO2% (r value −0.31; P=0.01, PSD and FEV1% (r value 0.71; P=0.0005, and PSD and FVC% (r value 0.63; P=0.003. Conclusions. The oxygen supply alterations might determine hypoxia of the ganglion cells causing a decrease of receptive optic nerve fiber activity. This method could be also useful to evaluate indirectly pulmonary activity of the CF disease.

  17. Optometry/Ophthalmology Assistants, AFSC 4V0X1/A

    Science.gov (United States)

    1994-07-01

    foreign bodies 4 F256 Remove nonembedded nonmetallic ocular foreign bodies 0019 Training 1 D80 Administer or score training tests 2 D85 Conduct...F207 Perform accommodation tests using Prince Rule devices 13 F221 Perform central visual fields tests using Tangent Screen 14 F243 Perform plus lens...tests using Reichert XPERT 91 F238 Perform NCT tests using other than Reichert XPERT or Reichert NCT I or NCT II 92 F239 Perform night vision goggles

  18. Ocular burns in an ophthalmology referral center in Santiago de Cali, Colombia.

    Directory of Open Access Journals (Sweden)

    Hugo Hernán Ocampo

    2009-11-01

    Full Text Available Introducción: Las quemaduras oculares son un problema de salud pública debido a la poca conciencia sobre protección ocular, la morbilidad y la severidad de las secuelas cuando se presentan. El objetivo de este estudio es caracterizar las quemaduras oculares intencionales y no intencionales en el Servicio de Oftalmología del Hospital Universitario del Valle (SO-HUV. Metodología: Serie de casos de 330 historias clínicas de pacientes con diagnóstico de quemadura ocular atendidos en el SO-HUV entre el año 2005 y 2006. Se realizó un análisis descriptivo univariado utilizando el programa Epi2000. Resultados: Se hallaron 249 personas con 342 ojos afectados; la mayoría de la población estaba entre los 19 y 45 años de edad con una media de 28 (DE±16.6. La relación hombre:mujer fue 2:1. Las quemaduras por lesiones no intencionales fueron 97.2% y por lesiones intencionales 2.8%. En el hogar se presentó 50.2% de las quemaduras y en el trabajo 39.4%. Las lesiones causadas por químicos fueron 62.7%, por térmicos 28.9% y por radiación ultravioleta 6.8%. Se hizo el manejo específico a cada tipo de quemadura y refirieron mejoría 97.7% de los pacientes que acudieron a los controles. Las secuelas más comunes fueron disminución de la agudeza visual en 25 (10% pacientes y la córnea blanca en 7 (2.8% pacientes; la causa principal fueron los químicos. Conclusiones: Las quemaduras oculares son producidas por eventos prevenibles en su mayoría y es importante orientar programas de promoción y prevención en torno a estas lesiones.

  19. 78 FR 76842 - Food and Drug Administration/American Academy of Ophthalmology Workshop on Developing Novel...

    Science.gov (United States)

    2013-12-19

    .... Participants will then engage in in- depth discussions of the pros and cons of various methods used to assess... never attended a Connect Pro event before, test your connection at https://collaboration.fda.gov/common/help/en/support/meeting_test.htm . To get a quick overview of the Connect Pro program, visit...

  20. VEP asymmetry with ophthalmological and MRI findings in two achiasmatic children.

    Science.gov (United States)

    Brecelj, Jelka; Stirn-Kranjc, Branka; Pecaric-Meglic, Nuska; Skrbec, Miha

    2007-03-01

    Achiasmia is a rarely diagnosed visual pathway maldevelopment where all or the majority of nasal retinal fibres fail to decussate at the optic chiasm. It has been identified by neuroimaging and also by visual evoked potential (VEP) asymmetry. VEP asymmetry has not been defined consistently in previous studies. The aim was to study VEP asymmetry to flash stimulation in two children with maldevelopment of the optic chiasm in comparison to control children. Both children had congenital nystagmus, optic nerve hypoplasia with a bilateral small double ring, bitemporal visual field defect and normal colour vision. In child 1 visual acuity in both eyes was 0.1, in child 2 it was 0.2. MRI showed reduced chiasmal size in child 1, while in child 2 it was combined with other midline abnormalities. VEP to monocular flash stimulation showed in both children distinctive occipital distribution, which was not observed in control children. The N2 wave was distributed asymmetrically over the ipsilateral hemisphere to the stimulated eye, while the P2 wave was distributed over both hemispheres. The P2 wave was however better defined over the ipsilateral hemisphere. Flash VEP occipital distribution remained similar in child 1, who was followed from 10 months to 9 years. These cases of achiasmia demonstrate a distinctive VEP asymmetry in the distribution of the flash VEP N2 wave, as well as the expected structural defect determined by neuroimaging.