WorldWideScience

Sample records for operating procedures sops

  1. 78 FR 26103 - Proposed Standard Operating Procedure (SOP) of the Aircraft Certification Service (AIR) Project...

    Science.gov (United States)

    2013-05-03

    ... Federal Aviation Administration Proposed Standard Operating Procedure (SOP) of the Aircraft Certification... comments on, the Aircraft Certification Service (AIR) standard operating procedure (SOP) describing the... comments on the SOP to: Federal Aviation Administration (FAA) Aircraft Certification Service,...

  2. EDRN Standard Operating Procedures (SOP) — EDRN Public Portal

    Science.gov (United States)

    The NCI’s Early Detection Research Network is developing a number of standard operating procedures for assays, methods, and protocols for collection and processing of biological samples, and other reference materials to assist investigators to conduct experiments in a consistent, reliable manner. These SOPs are established by the investigators of the Early Detection Research Network to maintain constancy throughout the Network. These SOPs represent neither a consensus, nor are the recommendations of NCI.

  3. HIPAA: SOP: HIPAA as standard operating procedures.

    Science.gov (United States)

    Kiel, Joan M

    2010-01-01

    Upon the debut of the Health Insurance Portability and Accountability Act (HIPAA), many health care managers felt that the implementation process would be too expensive, arduous, and time-consuming. Now, several years later, it is clear that the way to manage HIPAA is to make it a part of one's standard operating procedures. Using this approach, HIPAA is cost-effective, manageable, and efficient. Health care managers can utilize the step-by-step procedures presented here to efficaciously implement and manage HIPAA.

  4. 76 FR 54528 - Standard Operating Procedures (SOP) of the Aircraft Certification Service (AIR) Process for the...

    Science.gov (United States)

    2011-09-01

    ... Federal Aviation Administration Standard Operating Procedures (SOP) of the Aircraft Certification Service...) standard operating procedure (SOP) describing the process used to sequence certification projects that are... before October 3, 2011. ADDRESSES: Send all comments on the SOP : AIR-100-001; Standard...

  5. Towards a Library of Standard Operating Procedures (SOPs) for (meta)genomic annotation

    Energy Technology Data Exchange (ETDEWEB)

    Kyrpides, Nikos; Angiuoli, Samuel V.; Cochrane, Guy; Field, Dawn; Garrity, George; Gussman, Aaron; Kodira, Chinnappa D.; Klimke, William; Kyrpides, Nikos; Madupu, Ramana; Markowitz, Victor; Tatusova, Tatiana; Thomson, Nick; White, Owen

    2008-04-01

    Genome annotations describe the features of genomes and accompany sequences in genome databases. The methodologies used to generate genome annotation are diverse and typically vary amongst groups. Descriptions of the annotation procedure are helpful in interpreting genome annotation data. Standard Operating Procedures (SOPs) for genome annotation describe the processes that generate genome annotations. Some groups are currently documenting procedures but standards are lacking for structure and content of annotation SOPs. In addition, there is no central repository to store and disseminate procedures and protocols for genome annotation. We highlight the importance of SOPs for genome annotation and endorse a central online repository of SOPs.

  6. Towards a Library of Standard Operating Procedures (SOPs) for (meta)genomic annotation

    Energy Technology Data Exchange (ETDEWEB)

    Kyrpides, Nikos; Angiuoli, Samuel V.; Cochrane, Guy; Field, Dawn; Garrity, George; Gussman, Aaron; Kodira, Chinnappa D.; Klimke, William; Kyrpides, Nikos; Madupu, Ramana; Markowitz, Victor; Tatusova, Tatiana; Thomson, Nick; White, Owen

    2008-04-01

    Genome annotations describe the features of genomes and accompany sequences in genome databases. The methodologies used to generate genome annotation are diverse and typically vary amongst groups. Descriptions of the annotation procedure are helpful in interpreting genome annotation data. Standard Operating Procedures (SOPs) for genome annotation describe the processes that generate genome annotations. Some groups are currently documenting procedures but standards are lacking for structure and content of annotation SOPs. In addition, there is no central repository to store and disseminate procedures and protocols for genome annotation. We highlight the importance of SOPs for genome annotation and endorse a central online repository of SOPs.

  7. Overview of the Standing Operating Procedure (SOP) for the development of Provisional Advisory Levels (PALs).

    Science.gov (United States)

    Young, Robert A; Bast, Cheryl B; Wood, Carol S; Adeshina, Femi

    2009-12-01

    Provisional Advisory Levels (PALs) are concentrations in air and drinking water for priority toxic chemicals. This article summarizes the Standing Operating Procedure (SOP) currently in place for the data-driven development of chemical-specific PALs. To provide consistency and transparency, and to avoid faults of arbitrariness, the SOP was developed for guidance in deriving PAL values. Three levels (PAL 1, PAL 2, and PAL 3), distinguished by severity of toxic effects, are developed for 24-hour, 30-day, 90-day, and 2-year durations of potential drinking water and inhalation exposures for the general public. The SOP for PAL development focuses on (1) data acquisition and analysis, (2) identification of a chemical-specific critical effect, (3) selection of a quantitative point-of-departure (POD), (4) uncertainty analysis and adjustments, (5) exposure duration adjustment and extrapolation, (6) identification of special concerns and issues, and (7) verification, documentation, and dissemination of PALs. To avoid uncompromising rigidity in deriving PAL values and to allow for incorporation of new or refined methodologies, the overall procedure is fluid and subject to modification. The purpose of this publication is to provide a summary of this SOP.

  8. [The implementation of an independent and differentiated pain management SOP (Standard Operating Procedure) for the interdisciplinary intensive care unit].

    Science.gov (United States)

    Aust, Hansjörg; Wulf, Hinnerk; Vassiliou, Timon

    2013-03-01

    Up to the present day, pain management in the ICU (Intensive Care Units) is a unresolved clinical problem due to patient heterogeneity with complex variation in etiopathology and treatment of the underlying diseases. Therefore, therapeutic strategies in terms of standard operating procedure (SOP) are a necessary to improve the pain management for intensive care patients. Common guidelines for analgosedation are often inadequate to reflect the clinical situation. In particular, for an ICU setting without permanent presence of a physician a missing pain management SOP resulting in delayed pain therapy caused by a therapeutic uncertainty of the nurse staff. In addition to our pre-existing SOP for analgosedation we implemented a pain management SOP for our interdisciplinary, anaesthesiologic ICU. A exploratory survey among the nurse staff was conducted to assess the efficacy of the SOP. The results of the evaluation after a 6 month follow-up indicated a faster onset of pain management and good acceptance by the nursing staff.

  9. CTEPP STANDARD OPERATING PROCEDURE FOR PRE-CLEANING FILTERS AND XAD-2 (SOP-5.10)

    Science.gov (United States)

    This SOP summarizes the method for pre-cleaning XAD-2 resin and quartz fiber filters. The procedure provides a cleaning method to help reduce potential background contamination in the resin and filters.

  10. [Advantages and disadvantages of different methods for the implementation and the support of standard operating procedures: From PDF files to an app- and webbased SOP management system].

    Science.gov (United States)

    Bauer, M; Riech, S; Brandes, I; Waeschle, R M

    2015-11-01

    The quality assurance of care and patient safety, with increasing cost pressure and performance levels is of major importance in the high-risk and high cost area of the operating room (OR). Standard operating procedures (SOP) are an established tool for structuring and standardization of the clinical treatment pathways and show multiple benefits for quality assurance and process optimization. An internal project was initiated in the department of anesthesiology and a continuous improvement process was carried out to build up a comprehensive SOP library. In the first step the spectrum of procedures in anesthesiology was transferred to PDF-based SOPs. The further development to an app-based SOP library (Aesculapp) was due to the high resource expenditure for the administration and maintenance of the large PDF-based SOP collection and to deficits in the mobile availability. The next developmental stage, the SOP healthcare information assistant (SOPHIA) included a simplified and advanced update feature, an archive feature previously missing and notably the possibility to share the SOP library with other departments including the option to adapt each SOP to the individual situation. A survey of the personnel showed that the app-based allocation of SOPs (Aesculapp, SOPHIA) had a higher acceptance than the PDF-based developmental stage SOP form. The SOP management system SOPHIA combines the benefits of the forerunner version Aesculapp with improved options for intradepartmental maintenance and administration of the SOPs and the possibility of an export and editing function for interinstitutional exchange of SOPs.

  11. CTEPP STANDARD OPERATING PROCEDURE FOR CONDUCTING INTERNAL FIELD AUDITS AND QUALITY CONTROL (SOP-2.25)

    Science.gov (United States)

    This SOP describes the method for conducting internal field audits and quality control procedures. Internal field audits will be conducted to ensure the collection of high quality data. Internal field audits will be conducted by Field Auditors (the Field QA Officer and the Field...

  12. CTEPP STANDARD OPERATING PROCEDURE FOR SAMPLE SELECTION (SOP-1.10)

    Science.gov (United States)

    The procedures for selecting CTEPP study subjects are described in the SOP. The primary, county-level stratification is by region and urbanicity. Six sample counties in each of the two states (North Carolina and Ohio) are selected using stratified random sampling and reflect ...

  13. CTEPP STANDARD OPERATING PROCEDURE FOR TELEPHONE SAMPLE SUBJECTS RECRUITMENT (SOP-1.12)

    Science.gov (United States)

    The subject recruitment procedures for the telephone sample component are described in the SOP. A random telephone sample list is ordered from a commercial survey sampling firm. Using this list, introductory letters are sent to targeted homes prior to making initial telephone c...

  14. CTEPP STANDARD OPERATING PROCEDURE FOR CONDUCTING INTERNAL FIELD AUDITS AND QUALITY CONTROL (SOP-2.25)

    Science.gov (United States)

    This SOP describes the method for conducting internal field audits and quality control procedures. Internal field audits will be conducted to ensure the collection of high quality data. Internal field audits will be conducted by Field Auditors (the Field QA Officer and the Field...

  15. Evaluasi Penerapan Standard Operating Procedure-Good Agriculture Practice (SOP-GAP pada Usahatani Padi Organik di Kabupaten Bantul

    Directory of Open Access Journals (Sweden)

    Sriyadi Sriyadi

    2016-02-01

    Full Text Available Food security has meaning not only the availability of adequate food, but also providing security for producers and consumers and ensuring environmental sustainability for sustainable production. Organic farming systems are expected to solve the problem for realizing food security and enhancement of people's welfare. The results of research indicated that, (1 The implementation level of Standard Operating Procedure-Good Agriculture Practice (SOP-GAP of Organic Rice Farming in Bantul district was quite high, (2 The implementation level of SOP-GAP of Organic Rice Farming related to the availability of capital, the selling price and the purchase price of inputs (seeds and fertilizers, (3 The level of the farmer's decision related to the implementation level of SOP-GAP of organic rice farming, and (4 development of organic rice farming required availability of sufficient capital. In this regard the government, particularly the agriculture authority and food security agency need to disburse or facilitate capital for farmers in revolving as well as low interest loans.

  16. CTEPP STANDARD OPERATING PROCEDURE FOR PROCESSING COMPLETED DATA FORMS (SOP-4.10)

    Science.gov (United States)

    This SOP describes the methods for processing completed data forms. Key components of the SOP include (1) field editing, (2) data form Chain-of-Custody, (3) data processing verification, (4) coding, (5) data entry, (6) programming checks, (7) preparation of data dictionaries, cod...

  17. CTEPP STANDARD OPERATING PROCEDURE FOR RECORDING DATA COLLECTION FORMS (SOP-2.22)

    Science.gov (United States)

    This SOP describes the method for recording information onto the data collection forms. The data collection forms are organized into 10 modules: Recruitment Survey; House/Building Characteristics Observation Survey; Day Care Center/Building Characteristics Observation Survey; Par...

  18. CTEPP STANDARD OPERATING PROCEDURE FOR PACKING AND SHIPPING STUDY SAMPLES (SOP-3.11)

    Science.gov (United States)

    This SOP describes the methods for packing and shipping study samples. These methods are for packing and shipping biological and environmental samples. The methods have been tested and used in the previous pilot studies.

  19. CTEPP STANDARD OPERATING PROCEDURE FOR CONDUCTING STAFF AND PARTICIPANT TRAINING (SOP-2.27)

    Science.gov (United States)

    This SOP describes the method to train project staff and participants to collect various field samples and questionnaire data for the study. The training plan consists of two separate components: project staff training and participant training. Before project activities begin,...

  20. CTEPP STANDARD OPERATING PROCEDURE FOR HANDLING SAMPLE AND DATA CUSTODY (SOP-2.26)

    Science.gov (United States)

    This SOP describes the method for handling sample custody. A standardized Chain-of-Custody (CoC) Record is used to document the sample/data custody. Each participant is assigned one CoC Record for the samples/data collected at their home and/or day care center.

  1. CTEPP STANDARD OPERATING PROCEDURE FOR SHIPPING AND STORING DATA COLLECTION FORMS (SOP-3.12)

    Science.gov (United States)

    This SOP describes the method for shipping and storing data collection forms. All data collection forms will be processed in the Battelle North Carolina (NC) office. The Ohio field staff will ship the completed data collection forms to the Battelle NC office.

  2. CTEPP STANDARD OPERATING PROCEDURE FOR HANDLING MISSING SAMPLES AND DATA (SOP-2.24)

    Science.gov (United States)

    This SOP describes the method for handling missing samples or data. Missing samples or data will be identified as soon as possible during field sampling. It provides guidance to collect the missing sample or data and document the reason for the missing sample or data.

  3. CTEPP STANDARD OPERATING PROCEDURE FOR SETTING UP A HOUSEHOLD SAMPLING SCHEDULE (SOP-2.10)

    Science.gov (United States)

    This SOP describes the method for scheduling study subjects for field sampling activities in North Carolina (NC) and Ohio (OH). There are three field sampling teams with two staff members on each team. Two field sampling teams collect the field data simultaneously. A third fiel...

  4. CTEPP STANDARD OPERATING PROCEDURE FOR VIDEOTAPING CHILD ACTIVITIES (SOP-2.23)

    Science.gov (United States)

    This SOP describes the method for videotaping a preschool child at a home. The CTEPP main study will collect multimedia samples and questionnaire data at the homes of participants (adults and children) during 48-hr sampling periods. Videotaping the activities of 10% of these chi...

  5. Development and evaluation of Standard Operating Procedures (SOPs) for quality control tests and radiological protection activities in a Nuclear Medicine Service

    Energy Technology Data Exchange (ETDEWEB)

    Krempser, Alexandre R., E-mail: krempser@peb.ufrj.br [Universidade Federal do Rio de Janeiro (PEB/COPPE/UFRJ), RJ (Brazil). Programa de Engenharia Biomedica; Soares, Alexandre B. [Universidade Federal do Rio de Janeiro (IF/UFRJ), Rio de Janeiro, RJ (Brazil). Inst. de Fisica; Corbo, Rossana [Universidade Federal do Rio de Janeiro (FM/UFRJ), Rio de Janeiro, RJ (Brazil). Dept. de Radiologia

    2011-07-01

    The quality management in Nuclear Medicine Services is a requirement of national and international standards. The Brazilian regulatory agency in health surveillance, the Agencia Nacional de Vigilancia Sanitaria (ANVISA), in its Resolucao de Diretoria Colegiada (Collegiate Directory Resolution) no. 38, requires the elaboration of documents describing the technical and clinical routine activities. This study aimed to elaborate, implement and evaluate Standard Operating Procedures (SOPs) for quality control tests and radiological protection activities in the Nuclear Medicine Service of a university hospital. Eighteen SOPs were developed, involving tasks related to dose calibrator, gamma camera, Geiger-Muller detectors and radiological protection activities. The performance of its application was evaluated for a period of six months. It was observed a reduction in 75% of reported operational errors and 42% of the number of reported incidents with contamination by radioactive material. The SOPs were adequate and successful in its application. New procedures involving clinical activities will also be developed and evaluated. (author)

  6. CTEPP STANDARD OPERATING PROCEDURE FOR COLLECTION OF DISLODGEABLE RESIDUES -- PUF ROLLER SAMPLES FOR PERSISTENT ORGANIC POLLUTANTS (SOP-2.18)

    Science.gov (United States)

    This SOP describes the method to collect transferable residues from indoor floor surfaces. The sampling procedures described are applicable to bare floors or covered floor surfaces, e.g., carpeting and vinyl flooring. The samples will be collected only in the day care centers o...

  7. 标准作业流程(SOP)在神华煤炭企业的应用%Application of standard operation procedure in Shenhua coal enterprise

    Institute of Scientific and Technical Information of China (English)

    张玉华; 苏慎忠; 田志伟

    2014-01-01

    实施标准作业流程SOP(Standard Operation Procedure)已经成为提高煤炭企业竞争力的重要手段.通过对标准作业流程SOP在煤炭企业应用的探索与研究,探讨煤炭企业实施SOP意义,为企业工艺质量管理做好保障.

  8. CTEPP STANDARD OPERATING PROCEDURE FOR TRANSLATING VIDEOTAPES OF CHILD ACTIVITIES (SOP-4.13)

    Science.gov (United States)

    The EPA will conduct a two-day video translation workshop to demonstrate to coders the procedures for translating the activity patterns of preschool children on videotape. The coders will be required to pass reliability tests to successfully complete the training requirements of ...

  9. Determination of Nanomechanical Properties by Atomic Force Microscopy: Scientific Operating Procedure SOP-C-#

    Science.gov (United States)

    2015-02-01

    aspect of this collection of infor mati on, incl uding suggestions for reducing this burden to Department of Defense, Washington Headquarters Ser...vices , Directorate for Infor mati on Operations and Reports (0704-0188), 1215 Jefferson Davis Highway, Suite 1204, Arlington, VA 22202-4302

  10. CTEPP STANDARD OPERATING PROCEDURE FOR EXTRACTING AND PREPARING SOLID FOOD SAMPLES FOR ANALYSIS OF PERSISTENT ORGANIC POLLUTANTS (SOP-5.20)

    Science.gov (United States)

    This SOP describes the procedures for homogenizing, extracting and concentrating solid food samples for persistent organic pollutants such as organochlorine compounds, organophosphate compounds, polycyclic aromatic hydrocarbons, polychlorinated biphenyls, substituted phenols, and...

  11. CTEPP STANDARD OPERATING PROCEDURE FOR EXTRACTING AND PREPARING LIQUID FOOD SAMPLES FOR ANALYSIS OF PERSISTENT ORGANIC POLLUTANTS (SOP-5.19)

    Science.gov (United States)

    This SOP describes the procedures for homogenizing, extracting, and concentrating liquid food samples for neutral persistent organic pollutants such as organochlorine compounds, organophosphate compounds, polycyclic aromatic hydrocarbons, polychlorinated biphenyls, and phenols.

  12. CTEPP STANDARD OPERATING PROCEDURE FOR EXTRACTING AND PREPARING SOLID FOOD SAMPLES FOR ANALYSIS OF PERSISTENT ORGANIC POLLUTANTS (SOP-5.20)

    Science.gov (United States)

    This SOP describes the procedures for homogenizing, extracting and concentrating solid food samples for persistent organic pollutants such as organochlorine compounds, organophosphate compounds, polycyclic aromatic hydrocarbons, polychlorinated biphenyls, substituted phenols, and...

  13. CTEPP STANDARD OPERATING PROCEDURE FOR EXTRACTING AND PREPARING LIQUID FOOD SAMPLES FOR ANALYSIS OF PERSISTENT ORGANIC POLLUTANTS (SOP-5.19)

    Science.gov (United States)

    This SOP describes the procedures for homogenizing, extracting, and concentrating liquid food samples for neutral persistent organic pollutants such as organochlorine compounds, organophosphate compounds, polycyclic aromatic hydrocarbons, polychlorinated biphenyls, and phenols.

  14. International Cooperation to Establish Standard Operating Procedure (SOP) for Quarantine Management of Irradiated Foods in International Trade

    Energy Technology Data Exchange (ETDEWEB)

    Lee, J. W.; Byun, M. W.; Kim, J. H.; Choi, J. I.; Song, B. S.; Yoon, Y. H.; Kim, D. H.; Kim, W. G.; Kim, K. P.

    2010-02-15

    {center_dot} Development of SOPs through various research activities such as building international cooperation, and analysing current status of food irradiation in domestic and international markets, export and import, international market size, and of R and D - Analysis of examples for quarantine management in agricultural product exporting countries and use of irradiation technology for agricultural product quarantine, and changes in international quarantine management - Analysis of SOPs for food irradiation quarantine in international organization (CODEX, IPPC, WHO). U.S, EU, China, India, and Australia. - Collaborative researches of India/Korea and China/Korea entered into an agreement for market trials {center_dot} Publishment of irradiation quarantine management SOPs agreed to CODEX standards - Collaborative researches for quarantine management, avoiding Technical Barrier to Trade (TBT), and Sanitary Phytosanitary Measures were conducted, and advanced SOPs agreed with WTO/FTA system were published

  15. CTEPP STANDARD OPERATING PROCEDURE FOR ENTERING OR IMPORTING ELECTRONIC DATA INTO THE CTEPP DATABASE (SOP-4.12)

    Science.gov (United States)

    This SOP described the method used to automatically parse analytical data generated from gas chromatography/mass spectrometry (GC/MS) analyses into CTEPP summary spreadsheets and electronically import the summary spreadsheets into the CTEPP study database.

  16. CTEPP STANDARD OPERATING PROCEDURE FOR MAINTAINING AND RECORDING ELECTRONIC CHAIN-OF-CUSTODY (SOP-4.11)

    Science.gov (United States)

    The method for maintaining and recording electronic Chain-of-Custody (CoC) Records for CTEPP samples is summarized in this SOP. The CoC Records that will be logged electronically include the creation of a sample's identification code, bar code labels, and hard-copy CoC document...

  17. Sample Preparation of Nano-sized Inorganic Materials for Scanning Electron Microscopy or Transmission Electron Microscopy: Scientific Operating Procedure SOP-P-2

    Science.gov (United States)

    2015-07-01

    present other challenges, as destruction of detail structures may occur because this technique involves air drying, which may collapse cell...Procedure SOP-P-2 Charles A. Weiss, Jr., and Robert D. Moser Geotechnical and Structures Laboratory U.S. Army Engineer Research and Development...conductors and may need to be coated to passivate the surface so that electrons from the electron beam are carried from the surface. Certain metal

  18. Environmental Sciences Division Toxicology Laboratory standard operating procedures

    Energy Technology Data Exchange (ETDEWEB)

    Kszos, L.A.; Stewart, A.J.; Wicker, L.F.; Logsdon, G.M.

    1989-09-01

    This document was developed to provide the personnel working in the Environmental Sciences Division's Toxicology Laboratory with documented methods for conducting toxicity tests. The document consists of two parts. The first part includes the standard operating procedures (SOPs) that are used by the laboratory in conducting toxicity tests. The second part includes reference procedures from the US Environmental Protection Agency document entitled Short-Term Methods for Estimating the Chronic Toxicity of Effluents and Receiving Waters to Freshwater Organisms, upon which the Toxicology Laboratory's SOPs are based. Five of the SOPs include procedures for preparing Ceriodaphnia survival and reproduction test. These SOPs include procedures for preparing Ceriodaphnia food (SOP-3), maintaining Ceriodaphnia cultures (SOP-4), conducting the toxicity test (SOP-13), analyzing the test data (SOP-13), and conducting a Ceriodaphnia reference test (SOP-15). Five additional SOPs relate specifically to the fathead minnow (Pimephales promelas) larval survival and growth test: methods for preparing fathead minnow larvae food (SOP-5), maintaining fathead minnow cultures (SOP-6), conducting the toxicity test (SOP-9), analyzing the test data (SOP-12), and conducting a fathead minnow reference test (DOP-14). The six remaining SOPs describe methods that are used with either or both tests: preparation of control/dilution water (SOP-1), washing of glassware (SOP-2), collection and handling of samples (SOP-7), preparation of samples (SOP-8), performance of chemical analyses (SOP-11), and data logging and care of technical notebooks (SOP-16).

  19. Surface Area Analysis Using the Brunauer-Emmett-Teller (BET) Method: Standard Operating Procedure Series: SOP-C

    Science.gov (United States)

    2016-09-01

    www.erdc.usace.army.mil. To search for other technical reports published by ERDC, visit the ERDC online library at http://acwc.sdp.sirsi.net/client/default...the analysis. DISCLAIMER: The contents of this report are not to be used for advertising , publication, or promotional purposes. Citation of trade...Procedures link to the ERDC NanoGRID (Guidance for Risk Informed Deployment) framework for testing the exposure and hazard of nanotechnology Environmental

  20. CTEPP STANDARD OPERATING PROCEDURE FOR EXTRACTING AND PREPARING AIR SAMPLES FOR ANALYSIS OF POLAR PERSISTENT ORGANIC POLLUTANTS (SOP-5.13)

    Science.gov (United States)

    The method for extracting and preparing indoor and outdoor air samples for analysis of polar persistent organic pollutants is summarized in this SOP. It covers the preparation of samples that are to be analyzed by gas chromatography/mass spectrometry.

  1. CTEPP STANDARD OPERATING PROCEDURE FOR EXTRACTING AND PREPARING DUST AND SOIL SAMPLES FOR ANALYSIS OF NEUTRAL PERSISTENT ORGANIC POLLUTANTS (SOP-5.14)

    Science.gov (United States)

    This SOP summarizes the method for extracting and preparing a dust or soil sample for analysis of neutral persistent organic pollutants. It covers the extraction and concentration of samples that are to be analyzed by gas chromatography/mass spectrometry.

  2. CTEPP STANDARD OPERATING PROCEDURE FOR EXTRACTING AND PREPARING DRINKING WATER SAMPLES FOR ANALYSIS OF PERSISTENT ORGANIC POLLUTANTS (SOP 5.23)

    Science.gov (United States)

    The method for extracting and preparing a drinking water sample for analysis of atrazine is summarized in this SOP. It covers the extraction and concentration of samples that are to be analyzed by gas chromatography/ mass spectrometry.

  3. CTEPP STANDARD OPERATING PROCEDURE FOR EXTRACTING AND PREPARING DUST AND SOIL SAMPLES FOR ANALYSIS OF NEUTRAL PERSISTENT ORGANIC POLLUTANTS (SOP-5.14)

    Science.gov (United States)

    This SOP summarizes the method for extracting and preparing a dust or soil sample for analysis of neutral persistent organic pollutants. It covers the extraction and concentration of samples that are to be analyzed by gas chromatography/mass spectrometry.

  4. CTEPP STANDARD OPERATING PROCEDURE FOR EXTRACTING AND PREPARING DRINKING WATER SAMPLES FOR ANALYSIS OF PERSISTENT ORGANIC POLLUTANTS (SOP 5.23)

    Science.gov (United States)

    The method for extracting and preparing a drinking water sample for analysis of atrazine is summarized in this SOP. It covers the extraction and concentration of samples that are to be analyzed by gas chromatography/ mass spectrometry.

  5. CTEPP STANDARD OPERATING PROCEDURE FOR EXTRACTING AND PREPARING AIR SAMPLES FOR ANALYSIS OF POLAR PERSISTENT ORGANIC POLLUTANTS (SOP-5.13)

    Science.gov (United States)

    The method for extracting and preparing indoor and outdoor air samples for analysis of polar persistent organic pollutants is summarized in this SOP. It covers the preparation of samples that are to be analyzed by gas chromatography/mass spectrometry.

  6. Standard operating procedures for clinical research departments.

    Science.gov (United States)

    Kee, Ashley Nichole

    2011-01-01

    A set of standard operating procedures (SOPs) provides a clinical research department with clear roles, responsibilities, and processes to ensure compliance, accuracy, and timeliness of data. SOPs also serve as a standardized training program for new employees. A practice may have an employee that can assist in the development of SOPs. There are also consultants that specialize in working with a practice to develop and write practice-specific SOPs. Making SOPs a priority will save a practice time and money in the long run and make the research practice more attractive to corporate study sponsors.

  7. CTEPP STANDARD OPERATING PROCEDURE FOR EXTRACTING AND PREPARING DERMAL WIPE SAMPLES FOR ANALYSIS OF NEUTRAL PERSISTENT ORGANIC POLLUTANTS (SOP-5.16)

    Science.gov (United States)

    The method for extracting and preparing a dermal (hand) wipe sample for analysis of neutral persistent organic pollutants is summarized in this SOP. It covers the extraction and concentration of samples that are to be analyzed by gas chromatography/mass spectrometry.

  8. CTEPP STANDARD OPERATING PROCEDURE FOR EXTRACTING AND PREPARING SURFACE WIPE FOR ANALYSIS OF NEUTRAL PERSISTENT ORGANIC POLLUTANTS (SOP-5.17)

    Science.gov (United States)

    This SOP summarizes the method for extracting and preparing a hard floor surface wipe or food preparation surface wipe sample for analysis of neutral persistent organic. It covers the extraction and concentration of samples that are to be analyzed by gas chromatography/mass spect...

  9. CTEPP STANDARD OPERATING PROCEDURE FOR EXTRACTING AND PREPARING DUST AND SOIL SAMPLES FOR ANALYSIS OF POLAR PERSISTENT ORGANIC POLLUTANTS (SOP-5.15)

    Science.gov (United States)

    The method for extracting and preparing a dust or soil sample for analysis of polar persistent organic pollutants is summarized in this SOP. It covers the extraction, concentration, and derivatization of samples that are to be analyzed by gas chromatography/mass spectrometry.

  10. CTEPP STANDARD OPERATING PROCEDURE FOR EXTRACTING AND PREPARING LIQUID FOOD SAMPLES FOR ANALYSIS OF POLAR ORGANIC POLLUTANTS (SOP-5.29)

    Science.gov (United States)

    This SOP describes the extraction and preparation of a liquid food sample for analysis of acidic persistent organic pollutants such as acid herbicides, pentachlorphenol, and 3,5,6-trichloro-2-phenol. It covers the extraction, concentration and derivatization of samples that are t...

  11. CTEPP STANDARD OPERATING PROCEDURE FOR EXTRACTING AND PREPARING SOLID FOOD SAMPLES FOR ANALYSIS OF POLAR ORGANIC POLLUTANTS (SOP-5.28)

    Science.gov (United States)

    This SOP describes the extraction and preparation of a solid food sample for analysis of acidic persistent organic pollutants such as acid herbicides, pentachlorphenol, and 3,5,6-trichloro-2-phenol. It covers the extraction, concentration and derivatization of samples that are to...

  12. CTEPP STANDARD OPERATING PROCEDURE FOR EXTRACTING AND PREPARING SOLID FOOD SAMPLES FOR ANALYSIS OF POLAR ORGANIC POLLUTANTS (SOP-5.28)

    Science.gov (United States)

    This SOP describes the extraction and preparation of a solid food sample for analysis of acidic persistent organic pollutants such as acid herbicides, pentachlorphenol, and 3,5,6-trichloro-2-phenol. It covers the extraction, concentration and derivatization of samples that are to...

  13. CTEPP STANDARD OPERATING PROCEDURE FOR EXTRACTING AND PREPARING LIQUID FOOD SAMPLES FOR ANALYSIS OF POLAR ORGANIC POLLUTANTS (SOP-5.29)

    Science.gov (United States)

    This SOP describes the extraction and preparation of a liquid food sample for analysis of acidic persistent organic pollutants such as acid herbicides, pentachlorphenol, and 3,5,6-trichloro-2-phenol. It covers the extraction, concentration and derivatization of samples that are t...

  14. CTEPP STANDARD OPERATING PROCEDURE FOR EXTRACTING AND PREPARING SURFACE WIPE FOR ANALYSIS OF NEUTRAL PERSISTENT ORGANIC POLLUTANTS (SOP-5.17)

    Science.gov (United States)

    This SOP summarizes the method for extracting and preparing a hard floor surface wipe or food preparation surface wipe sample for analysis of neutral persistent organic. It covers the extraction and concentration of samples that are to be analyzed by gas chromatography/mass spect...

  15. CTEPP STANDARD OPERATING PROCEDURE FOR EXTRACTING AND PREPARING DERMAL WIPE SAMPLES FOR ANALYSIS OF NEUTRAL PERSISTENT ORGANIC POLLUTANTS (SOP-5.16)

    Science.gov (United States)

    The method for extracting and preparing a dermal (hand) wipe sample for analysis of neutral persistent organic pollutants is summarized in this SOP. It covers the extraction and concentration of samples that are to be analyzed by gas chromatography/mass spectrometry.

  16. CTEPP STANDARD OPERATING PROCEDURE FOR EXTRACTING AND PREPARING DUST AND SOIL SAMPLES FOR ANALYSIS OF POLAR PERSISTENT ORGANIC POLLUTANTS (SOP-5.15)

    Science.gov (United States)

    The method for extracting and preparing a dust or soil sample for analysis of polar persistent organic pollutants is summarized in this SOP. It covers the extraction, concentration, and derivatization of samples that are to be analyzed by gas chromatography/mass spectrometry.

  17. CTEPP STANDARD OPERATING PROCEDURE FOR EXTRACTING AND PREPARING URINE SAMPLES FOR ANALYSIS OF HYDROXY POLYCYCLIC AROMATIC HYDROCARBONS, PENTACHLOROPHENOL AND 2,4-D (SOP-5.21)

    Science.gov (United States)

    The method for extracting and preparing urine samples for analysis of hydroxy-polycyclic aromatic hydrocarbons, pentachlorophenol and 2,4-D is summarized in this SOP. It covers the extraction, concentration and methylation of samples that are to be analyzed by gas chromatography/...

  18. CTEPP STANDARD OPERATING PROCEDURE FOR PREPARATION OF SURROGATE RECOVERY STANDARD AND INTERNAL STANDARD SOLUTIONS FOR POLAR TARGET ANALYTES (SOP-5.26)

    Science.gov (United States)

    This SOP describes the method used for preparing surrogate recovery standard and internal standard solutions for the analysis of polar target analytes. It also describes the method for preparing calibration standard solutions for polar analytes used for gas chromatography/mass sp...

  19. CTEPP STANDARD OPERATING PROCEDURE FOR PREPARATION OF SURROGATE RECOVERY STANDARD AND INTERNAL STANDARD SOLUTIONS FOR NEUTRAL TARGET ANALYTES (SOP-5.25)

    Science.gov (United States)

    This standard operating procedure describes the method used for preparing internal standard, surrogate recovery standard and calibration standard solutions for neutral analytes used for gas chromatography/mass spectrometry analysis.

  20. CTEPP STANDARD OPERATING PROCEDURE FOR DETECTION AND QUANTIFICATION OF TARGET ANALYTES BY GAS CHROMATOGRAPHY/MASS SPECTROMETRY (GC/MS) (SOP-5.24)

    Science.gov (United States)

    This standard operating procedure describes the method used for the determination of target analytes in sample extracts and related quality assurance/quality control sample extracts generated in the CTEPP study.

  1. CTEPP STANDARD OPERATING PROCEDURE FOR EXTRACTING AND PREPARING DERMAL WIPE AND SURFACE WIPE SAMPLES FOR ANALYSIS OF POLAR ORGANIC POLLUTANTS (SOP-5.27)

    Science.gov (United States)

    The method for extracting and preparing a dermal or surface wipe sample for analysis of acidic persistent organic pollutants is summarized in this standard operating procedure. It covers the extraction and concentration of samples that are to be analyzed by gas chromatography/mas...

  2. Pembuatan Standard Operating Procedure (SOP Service Desk Berdasarkan Kerangka Kerja Itil V3 dengan Menggunakan Metode Analisis Gap Layanan (Studi Kasus: PT. XYZ , Tangerang

    Directory of Open Access Journals (Sweden)

    Annisa Rachmi

    2014-09-01

    Full Text Available Penggunaan Teknologi Informasi di banyak perusahaan telah menjadi satu hal penting dalam meningkatkan efektifitas dan efisiensi operasional bisnis yang mendukung tercapainya tujuan perusahaan, termasuk juga PT XYZ. Unit fungsional service desk sangat dibutuhkan oleh PT XYZ dalam mendukung operasional TI dan menangani permasalahan yang muncul serta memonitor terkait penggunaan TI yang ada di dalam perusahaan. Adanya kebutuhan PT XYZ untuk menjadikan service desk menjadi unit yang dapat berjalan dengan baik sesuai dengan fungsinya, menunjukkan bahwa perlunya penerapan tata kelola TI untuk mengatur dan mengelola aktivitas service desk. Salah satu tata kelola TI yang dimaksud adalah berupa prosedur kerja. Kerangka kerja Information Technology Infrastructure Library (ITIL merupakan suatu best practice yang bertujuan secara berkelanjutan meningkatkan efisiensi operasional TI. Perancangan dan implementasi service desk berdasarkan kerangka kerja ITIL V3 di PT XYZ diperlukan dalam upaya meningkatkan layanan TI dan mengatasi masalah yang ada saat ini. Pembuatan SOP ini diinisialisasi dengan menggunakan metode analisis gap, proses-proses yang dimuat ke dalam SOP merupakan hasil analisis kesenjangan antara kondisi kekinian service desk PT XYZ dengan kondisi ideal service desk framework ITIL.

  3. Beach Point Test Site, Aberdeen Proving Ground, Edgewood Area, Maryland. Focused Feasibility Study, Final Quality Assurance Project Plan, Standard Operating Procedures (SOPs). Appendix A

    Science.gov (United States)

    1993-10-01

    Powell, Robert M., Clark, Don A., and Paul , Cynthia J.; 1991, Facilitated Transport of Inorganic Contaminants in Ground Water: Part II Colloidal...Transport In "EPA Environmental Research Brief EPA/600/M-91/040", July 1991 Puls, Robert W., Powell, Robert M., Bledsoe, Bert, Clark, Don A., and Paul ...1 of 2 STANDARD OPERATING PROCEDURE 022 SEDIMENT AND BENTIIIC MACROINVERTEBRATESAMPLING WITH ECKMAN GRAB 1.0 Scope and Application This standard

  4. Canal Creek Study Area, Aberdeen Proving Ground, Edgewood Area, Maryland. Groundwater Monitoring Plan, Final Quality Assurance Project Plan, Standard Operating Procedures (SOPs). Appendix A

    Science.gov (United States)

    1993-10-01

    023", December 1990 Puls, Robert W., Powell, Robert M., Clark, Don A., and Paul , Cynthia J.; 1991, Facilitated Transport of Inorganic Contaminants in...Bledsoe, Bert, Clark, Don A., and Paul , Cynthia J.; 1992, Metals in Ground Water: Sampling Artifacts and Reproducibility In "Hazardous Waste & Hazardous...Revision: 3 Page: 1 of 2 STANDARD OPERATING PROCEDURE 022 SEDIMENT AND BENTHIC MACROINVERTEBRATESAMPLING WITH ECKMAN GRAB * 1.0 Scope and Application

  5. 9 CFR 416.13 - Implementation of SOP's.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Implementation of SOP's. 416.13... SANITATION § 416.13 Implementation of SOP's. (a) Each official establishment shall conduct the pre-operational procedures in the Sanitation SOP's before the start of operations. (b) Each official...

  6. Standard Operating Procedures, MCSP Monarch and Plant Monitoring, 2016

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This record contains the six Standard Operating Procedure (SOP) of the initial survey instructions (ISI) developed and followed for surveys conducted as part of the...

  7. Investigation and analysis of clinical trial research nurse to perform standard operating procedures

    Institute of Scientific and Technical Information of China (English)

    Yan Lin; Yan-Yun Wu; Mei-Hua Wu; Xiu-Yu Yang; Ming Zhou

    2016-01-01

    Objective: The aim of this study was to investigate the situations and factors that cause nurses not to follow standard operating procedures (SOPs) during the clinical trial process. Methods: Five cases involving patients enrolled in a clinical trial were divided into two groups, pre-SOP training and post-SOP training, to compare and observe the process problems and whether nurses fol-lowed SOPs in clinical trials. The causes of problems were analyzed and corrective measures were proposed. Results: Our results indicate significant improvement in compliance with SOPs after training. There were three occurrences of irregular behavior after training compared with 21 occurrences of irregular behavior before training. Conclusions: The quality of clinical trials can be improved if nurses strictly follow SOPs.

  8. Standard operating procedure: implementation, critical analysis, and validation in the Audiology Department at CESTEH/Fiocruz.

    Science.gov (United States)

    Freitas, Anelisse Vasco Mascarenhas de; Quixabeiro, Elinaldo Leite; Luz, Geórgia Rosangela Soares; Franco, Viviane Moreira; Santos, Viviane Fontes Dos

    2016-01-01

    Evaluate three standard operational procedures (SOPs), regarding the application of the brainstem auditory evoked potential (BAEP) test, implemented by the Audiology Department of the Center for Studies in Occupational Health and Human Ecology (CESTEH) through the application of a questionnaire and to verify whether the SOPs are effective and assess the necessity for improvement. The study was conducted in three phases: in the first phase, eight speech-language pathologists and seven physicians, with no experience in BAEP, were instructed to read and perform each SOP, eventually all individuals evaluated the SOPs by responding to a questionnaire; in the second phase, the questionnaires were analyzed and the three SOP texts were reviewed; in the third phase, nine speech-language pathologists and six physicians, also with no experience in BAEP, read and re-evaluated the reviewed SOPs through a questionnaire. In the first phase, difficulties in understanding the texts were found, raising doubts about the procedures; however, every participant was able to perform the procedure as a whole. In the third phase, after the review, all individuals were able to perform the procedures appropriately and continuously without any doubts. The assessment of the SOPs by questionnaires showed the need for adaptation in the texts. After the texts were reviewed according to the suggestions of the health professionals, it was possible to observe that the SOPs assisted in the execution of the task, which was conducted without any difficulties or doubts, being regarded effective and ensuring quality to the service offered.

  9. Generating a comprehensive set of standard operating procedures for a biorepository network-The CTRNet experience.

    Science.gov (United States)

    Barnes, Rebecca; Albert, Monique; Damaraju, Sambasivarao; de Sousa-Hitzler, Jean; Kodeeswaran, Sugy; Mes-Masson, Anne-Marie; Watson, Peter; Schacter, Brent

    2013-12-01

    Despite the integral role of biorepositories in fueling translational research and the advancement of medicine, there are significant gaps in harmonization of biobanking practices, resulting in variable biospecimen collection, storage, and processing. This significantly impacts accurate downstream analysis and, in particular, creates a problem for biorepository networks or consortia. The Canadian Tumour Repository Network (CTRNet; www.ctrnet.ca ) is a consortium of Canadian tumor biorepositories that aims to enhance biobanking capacity and quality through standardization. To minimize the issue of variable biobanking practices throughout its network, CTRNet has developed and maintained a comprehensive set of 45 standard operating procedures (SOPs). There were four key elements to the CTRNet SOP development process: 1) an SOP development team was formed from members across CTRNet to co-produce each SOP; 2) a principal author was appointed with responsibility for overall coordination of the SOP development process; 3) the CTRNet Management Committee (composed of principal investigators for each member biorepository) reviewed/revised each SOP completed by the development team; and 4) external expert reviewers provided feedback and recommendations on each SOP. Once final Management Committee approval was obtained, the ratified SOP was published on the CTRNet website for public access. Since the SOPs were first published on the CTRNet website (June 2008), there have been approximately 15,000 downloads of one or more CTRNet SOPs/Policies by users from over 60 countries. In accordance with biobanking best practices, CTRNet performs an exhaustive review of its SOPs at set intervals, to coincide with each granting cycle. The last revision was completed in May 2012.

  10. Standard operating procedure to prepare agar phantoms

    Science.gov (United States)

    Souza, R. M.; Santos, T. Q.; Oliveira, D. P.; Souza, R. M.; Alvarenga, A. V.; Costa-Felix, R. P. B.

    2016-07-01

    Agar phantoms are widely used as soft tissue mimics and some preparation techniques are described in the literature. There are also standards that describe the recipe of a soft tissue mimicking material (TMM). However some details of manufacture process are not clearly defined. The standardization of the phantom's preparation can produce a metrological impact on the results of the acoustic properties measured. In this direction, this paper presents a standard operating procedure (SOP) to prepare the agar TMM described on the IEC 60601-237.

  11. Qualitative research within trials: developing a standard operating procedure for a clinical trials unit

    Science.gov (United States)

    2013-01-01

    Background Qualitative research methods are increasingly used within clinical trials to address broader research questions than can be addressed by quantitative methods alone. These methods enable health professionals, service users, and other stakeholders to contribute their views and experiences to evaluation of healthcare treatments, interventions, or policies, and influence the design of trials. Qualitative data often contribute information that is better able to reform policy or influence design. Methods Health services researchers, including trialists, clinicians, and qualitative researchers, worked collaboratively to develop a comprehensive portfolio of standard operating procedures (SOPs) for the West Wales Organisation for Rigorous Trials in Health (WWORTH), a clinical trials unit (CTU) at Swansea University, which has recently achieved registration with the UK Clinical Research Collaboration (UKCRC). Although the UKCRC requires a total of 25 SOPs from registered CTUs, WWORTH chose to add an additional qualitative-methods SOP (QM-SOP). Results The qualitative methods SOP (QM-SOP) defines good practice in designing and implementing qualitative components of trials, while allowing flexibility of approach and method. Its basic principles are that: qualitative researchers should be contributors from the start of trials with qualitative potential; the qualitative component should have clear aims; and the main study publication should report on the qualitative component. Conclusions We recommend that CTUs consider developing a QM-SOP to enhance the conduct of quantitative trials by adding qualitative data and analysis. We judge that this improves the value of quantitative trials, and contributes to the future development of multi-method trials. PMID:23433341

  12. Diagnosis and dosimetry of exposure to sulfur mustard: Development of a standard operating procedure for hemoglobin adducts: Exploratory research on albumin and keratin adducts

    NARCIS (Netherlands)

    Noort, D.; Fidder, A.; Jong, L.P.A. de; Schans, G.P. van der; Benschop, H.P.

    2000-01-01

    A standard operating procedure (SOP) for determination of the sulfur mustard adduct to the N-terminal valine in hemoglobin was developed. By using this SOP, it was found that the Nterminal valine adduct in globin of hairless guinea pigs and marmosets which had been exposed to sulfur mustard (0.5 LD5

  13. 核电厂SOP规程安注安喷操作界面优化研究%Optimization Research on SOP Operation Interface of Safety Injection and Containment Spray in Nuclear Power Plant

    Institute of Scientific and Technical Information of China (English)

    刘至; 殷中平; 李广

    2015-01-01

    状态导向法事故规程(以下简称SOP规程)在核电厂中的应用,提升了核电厂的事故处理能力,但现有的SOP规程组织架构在应对核电站常用的如安注、安喷等专设安全设施动作控制方面,仍存在自动动作确认复杂、需反复调用链接画面等不足. 通过对操作界面的优化研究,可以有效弥补SOP规程的不足. 对SOP规程操作界面优化研究的技术思路进行了综合介绍,给出了其技术要点,并与原SOP规程组织架构进行了分析对比.%The application of state oriented procedures ( SOP) in nuclear power plant enhances the capability of the nuclear power plant upon accident treatment; however the existing SOP organizational structure is insufficient in response to motion control of the engineered safety facilities, e. g. , safety injection and containment spray, etc. , for instance, the automatic action is complexly to be acknowledged, and the linked displays have to be called repeatedly. The deficiency of SOP can be effectively made up by optimization research of operation interface. The technical ideas of optimization research for SOP operation interface are elaborated comprehensively, and the technical points are given, the optimized technology and original SOP organization structure are analyzed and compared.

  14. Research on Application of Dealing FWLB Accidentwith SOP Procedure%SOP规程在FWLB事故应对中的应用研究

    Institute of Scientific and Technical Information of China (English)

    申亚欧; 付冉; 蒋孝蔚

    2015-01-01

    The State Oriented Procedure(SOP) is a new procedure system, which was oriented by finite NSSS states without diagnosing the initial events. It can cover all of the events/accidents and reduce the human mistakes. Therefore, it can be seen that SOP will be used widely in the future. Considering the sparsity of researches on application of SOP procedure, the applying SOP on dealing with FWLB accident is studied. The methodology has been developed and the results have been compared with the results based on EOP procedure, which is widely used at present. Research shows that both results based on SOP and EOP are similar, the methodology for applying SOP on dealing with FWLB thus been proved to be reasonable. This research provides a experience and reference for other application of SOP.%SOP是一种新兴的规程体系,其基于有限的NSSS状态进行导向,不需对初因事件进行鉴别,理论上可应对所有初因事件导致的事故工况,减少人因误差,电厂采用SOP规程是未来的发展趋势。鉴于目前鲜有针对SOP规程的应用研究,本文对SOP在FWLB事故中的应对进行了研究,建立了SOP应用于FWLB事故的方法,同时基于目前广泛使用的EOP规程进行了分析,以验证SOP方法的合理性。分析结果表明:基于SOP的结果与EOP结果相似,SOP在FWLB事故的应用方法是合理的。本文对于SOP规程在其他事故应对的应用研究有一定的借鉴。

  15. Involving service users in trials: developing a standard operating procedure.

    Science.gov (United States)

    Evans, Bridie Angela; Bedson, Emma; Bell, Philip; Hutchings, Hayley; Lowes, Lesley; Rea, David; Seagrove, Anne; Siebert, Stefan; Smith, Graham; Snooks, Helen; Thomas, Marie; Thorne, Kym; Russell, Ian

    2013-07-17

    Many funding bodies require researchers to actively involve service users in research to improve relevance, accountability and quality. Current guidance to researchers mainly discusses general principles. Formal guidance about how to involve service users operationally in the conduct of trials is lacking. We aimed to develop a standard operating procedure (SOP) to support researchers to involve service users in trials and rigorous studies. Researchers with experience of involving service users and service users who were contributing to trials collaborated with the West Wales Organisation for Rigorous Trials in Health, a registered clinical trials unit, to develop the SOP. Drafts were prepared in a Task and Finish Group, reviewed by all co-authors and amendments made. We articulated core principles, which defined equality of service users with all other research team members and collaborative processes underpinning the SOP, plus guidance on how to achieve these. We developed a framework for involving service users in research that defined minimum levels of collaboration plus additional consultation and decision-making opportunities. We recommended service users be involved throughout the life of a trial, including planning and development, data collection, analysis and dissemination, and listed tasks for collaboration. We listed people responsible for involving service users in studies and promoting an inclusive culture. We advocate actively involving service users as early as possible in the research process, with a minimum of two on all formal trial groups and committees. We propose that researchers protect at least 1% of their total research budget as a minimum resource to involve service users and allow enough time to facilitate active involvement. This SOP provides guidance to researchers to involve service users successfully in developing and conducting clinical trials and creating a culture of actively involving service users in research at all stages. The UK

  16. Standard Operating Procedure

    Science.gov (United States)

    1997-01-01

    l^m .:#,"■• y’’:>’£l’S ABO GROUP CONFIRMED |[ Rh OF .NEGATIVE UNITS CONFIRMED fe^/w’H’o’^Ä^ ■ •:.■.■:•• •■’ .Tv-v^l^.>’-V.^^V’ir;i-.^K-V.^’vV-i...using 0.02 ml of whole blood diluted with 5.98 ml of Drabkin’s reagent (1:251 dilution). 51 I. Measure the supernatant hemoglobin concentration...34NcUiod fef*ɜ 17-0? STANDARD OPERATING PROCEDURE Red Blood Cells Collected in the CPDA-1 800 ml Primary PVC Plastic Bag Collection System and

  17. 9 CFR 416.14 - Maintenance of Sanitation SOP's.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Maintenance of Sanitation SOP's. 416... ACT SANITATION § 416.14 Maintenance of Sanitation SOP's. Each official establishment shall routinely evaluate the effectiveness of the Sanitation SOP's and the procedures therein in preventing...

  18. Methodology of complexity analysis of Emergency Operating Procedures for Nuclear Power Plants; Metodologia de analisis de complejidad de Procedimientos de Operacion de Emergencia de Centrales Nucleares

    Energy Technology Data Exchange (ETDEWEB)

    Martorell, P.; Martorell, S.; Marton, I.; Pelayo, F.; Mendizabal, R.

    2013-07-01

    The Emergency Operating Procedures (SOPs) set out the stages and contain actions to be executed by an operator to respond to an emergency situation. Methodologies are being developed to assess aspects such as complexity, completeness and vulnerability of these procedures. A methodology is presented in this paper to develop a network topology POE and analysis focused on the same complexity as a fundamental attribute.

  19. Electronic Procedures for Medical Operations

    Science.gov (United States)

    2015-01-01

    Electronic procedures are replacing text-based documents for recording the steps in performing medical operations aboard the International Space Station. S&K Aerospace, LLC, has developed a content-based electronic system-based on the Extensible Markup Language (XML) standard-that separates text from formatting standards and tags items contained in procedures so they can be recognized by other electronic systems. For example, to change a standard format, electronic procedures are changed in a single batch process, and the entire body of procedures will have the new format. Procedures can be quickly searched to determine which are affected by software and hardware changes. Similarly, procedures are easily shared with other electronic systems. The system also enables real-time data capture and automatic bookmarking of current procedure steps. In Phase II of the project, S&K Aerospace developed a Procedure Representation Language (PRL) and tools to support the creation and maintenance of electronic procedures for medical operations. The goal is to develop these tools in such a way that new advances can be inserted easily, leading to an eventual medical decision support system.

  20. Standard Operating Procedures for Female Genital Sexual Pain

    DEFF Research Database (Denmark)

    Fugl-Meyer, Kerstin S; Bohm-Starke, Nina; Damsted Petersen, Christina

    2012-01-01

    Introduction.  Female genital sexual pain (GSP) is a common, distressing complaint in women of all ages that is underrecognized and undertreated. Definitions and terminology for female GSP are currently being debated. While some authors have suggested that GSP is not per se a sexual dysfunction......, but rather a localized genial pain syndrome, others adhere to using clearly sexually related terms such as dyspareunia and vaginismus. Aim.  The aims of this brief review are to present definitions of the different types of female GSP. Their etiology, incidence, prevalence, and comorbidity with somatic...... and psychological disorders are highlighted, and different somatic and psychological assessment and treatment modalities are discussed. Methods.  The Standard Operating Procedures (SOP) committee was composed of a chair and five additional experts. No corporate funding or remuneration was received. The authors...

  1. A standard operating protocol (SOP) and minimum data set (MDS) for nursing and medical handover: considerations for flexible standardization in developing electronic tools.

    Science.gov (United States)

    Turner, Paul; Wong, Ming Chao; Yee, Kwang Chien

    2009-01-01

    As part of Australia's participation in the World Health Organization, the Australian Commission on Safety and Quality in Health Care (ACSQHC) is the leading federal government technical agency involved in the area of clinical handover improvement. The ACSQHC has funded a range of handover improvement projects in Australia including one at the Royal Hobart Hospital (RHH), Tasmania. The RHH project aims to investigate the potential for generalizable and transferable clinical handover solutions throughout the medical and nursing disciplines. More specifically, this project produced an over-arching minimum data set (MDS) and over-arching standardized operating protocol (SOP) based on research work on nursing and medical shift-to-shift clinical handover in general medicine, general surgery and emergency medicine. The over-arching MDS consists of five headings: situational awareness, patient identification, history and information, responsibility and tasks and accountability. The over-arching SOP has five phases: preparation; design; implementation; evaluation; and maintenance. This paper provides an overview of the project and the approach taken. It considers the implications of these standardized operating protocols and minimum data sets for developing electronic clinical handover support tools. Significantly, the paper highlights a human-centred design approach that actively involves medical and nursing staff in data collection, analysis, interpretation, and systems design. This approach reveals the dangers of info-centrism when considering electronic tools, as information emerges as the only factor amongst many others that influence the efficiency and effectiveness of clinical handover.

  2. Cord Blood Transplantation Study (COBLT): cord blood bank standard operating procedures.

    Science.gov (United States)

    Fraser, J K; Cairo, M S; Wagner, E L; McCurdy, P R; Baxter-Lowe, L A; Carter, S L; Kernan, N A; Lill, M C; Slone, V; Wagner, J E; Wallas, C H; Kurtzberg, J

    1998-12-01

    In 1995, the National Heart Lung and Blood Institute (NHLBI) solicited requests for a proposal (RFP) entitled "Transplant Centers for Clinical Research on Transplantation of Umbilical Cord Stem and Progenitor Cells." Three banks, six transplant centers, and one medical coordinating center (MCC) (Table 1) were funded with the overall goal of banking cord blood units (CBU) using a single manual of operations. Furthermore, the clinical protocols to evaluate the transplant outcome for adult and pediatric recipients of these well-characterized CBU would be analyzed in a uniform fashion. Because of the intense interest of the transplantation community in the policies and procedures for cord blood collection and processing, the principal investigators of the cord blood banks (CBB) and NHLBI elected to submit for publication the rationale and an abridged, but detailed, version of the standard operating procedures (SOP) developed between October 1996 and July 1998 prior to the initiation of the clinical protocols to be performed with these CBU. As the SOP will be refined over time, the complete SOP and subsequent amendments will be published and continually updated on the websites from the MCC-The EMMES Corporation (www.EMMES.com). All forms referred to in this document may be obtained from the EMMES website. It is hoped that the publication of this document will lay down a framework that will not only facilitate the development of other CBB but also help us more rapidly define what constitutes an "acceptable" CBU product.

  3. Quantifying Nanoparticle Release from Nanotechnology: Scientific Operating Procedure Series: SOP C 3

    Science.gov (United States)

    2017-02-01

    metalloids Optical Absorption Spectroscopy ppb-ppm Ag, Au, carbon nanotubes , graphene, graphite, Fullerenes, quantum dots Emission Spectroscopy...ISO Headquarters. ISO. 2012. Nanotechnologies - Characterization of Single-Wall Carbon Nanotubes Using Transmission Electron Microscopy. ISO/TS...also their size (ISO, 2015c; Creighton and Eadon, 1991; Kelly et al., 2003). Aromatic organic species such as carbon nanotubes , graphene, or ERDC/EL

  4. Nanomaterial Dispersion/Dissolution Characterization: Scientific Operating Procedure SOP-F-1

    Science.gov (United States)

    2016-05-01

    16 Table 3. Z-averages and PDIs for nAg particles in different media based on cumulant analysis...of the reference material as 36 nm, with a polydispersity index ( PDI ) of 0.11, indicative of a monodisperse material. While the nAg’s calculated Z...average in DI water (ranging from 35 to 37 nm) was statistically indistinguishable from the reference suspension, the PDI was significantly higher

  5. Purification and Concentration of Nanoparticles Using Diafiltration: Scientific Operating Procedure Series: SOP-P-1

    Science.gov (United States)

    2015-07-01

    ER D C/ EL S R- 15 -4 Environmental Consequences of Nanotechnologies Purification and Concentration of Nanoparticles Using...Environmental Consequences of Nanotechnologies ERDC/EL SR-15-4 July 2015 Purification and Concentration of Nanoparticles Using Diafiltration...platinum nanoparticles (as measured by atomic force microscopy (AFM)) was altered relative to the type and concentration of impurities. Gold nanoparticles

  6. Abrasion Testing of Products Containing Nanomaterials, SOP-R-2: Scientific Operating Procedure Series: Release (R)

    Science.gov (United States)

    2016-04-01

    sanding process with matrix materials containing nanofillers led to the conclusion that the rigidity of matrix, rather than the presence of...nanoparticles released during construction of photocatalytic pavements using engineered nanoparticles. Journal of Nanoparticle Research 14(4): 1-15

  7. FFTF operations procedures preparation guide. Revision 2

    Energy Technology Data Exchange (ETDEWEB)

    1976-12-01

    The Guide is intended to provide guidelines for the initial preparation of FFTF Operating Procedures. The Procedures Preparation Guide was developed from the plan presented and approved in the FFTF Reactor Plant Procedures Plan, PC-1, Revision 3.

  8. National Ignition Facility (NIF) operations procedures plan

    Energy Technology Data Exchange (ETDEWEB)

    Mantrom, D.

    1998-05-06

    The purpose of this Operations Procedures Plan is to establish a standard procedure which outlines how NIF Operations procedures will be developed (i.e , written, edited, reviewed, approved, published, revised) and accessed by the NIF Operations staff who must use procedures in order to accomplish their tasks. In addition, this Plan is designed to provide a guide to the NIF Project staff to assist them in planning and writing procedures. Also, resource and scheduling information is provided.

  9. 加快中医药实验室标准操作程序(SOP)建设%Accelerating the Pace of Setting up Standard Operation Practice in Laboratory of TCM

    Institute of Scientific and Technical Information of China (English)

    张丽; 牛建昭

    2000-01-01

    1999年,北京中医药大学按照GLP的要求对实验室进行了规范化管理,结合申报国家中医药管理局三级实验室,率先在中医院校开展了标准操作程序(SOP,Standard Operation Procedure)的制字工作.SOP是将操作过程用书面的形式记录下来,即要求形成语言简洁、明确的指令性书面文件,使其操作有章可循,作到标准化、规范化.SOP的制定要有科学性、合理性和可操作性,要有极高的重现性、稳定性和可遵循性.它使实验操作更具体、更详细,更易于掌握,是实验方法技术和注意事项等多方面的指南.SOP的制定和执行是一个漫长而艰巨的工程,是中医走向世界的重要步骤.SOP的制定将加快中医药行业走向世界的步伐.

  10. [Advanced Trauma Life Support (ATLS) in the emergency room. Is it suitable as an SOP?].

    Science.gov (United States)

    Shafizadeh, S; Tjardes, T; Steinhausen, E; Balke, M; Paffrath, T; Bouillon, B; Bäthis, H

    2010-08-01

    There is clinical evidence that a standardized management of trauma patients in the emergency room improves outcome. ATLS is a training course that teaches a systematic approach to the trauma patient in the emergency room. The aims are a rapid and accurate assessment of the patient's physiologic status, treatment according to priorities, and making decisions on whether the local resources are sufficient for adequate definitive treatment of the patient or if transfer to a trauma center is necessary. Above all it is important to prevent secondary injury, to realize timing as a relevant factor in the initial treatment, and to assure a high standard of care. A standard operating procedure (SOP) exactly regulates the approach to trauma patients and determines the responsibilities of the involved faculties. An SOP moreover incorporates the organizational structure in the treatment of trauma patients as well as the necessary technical equipment and staff requirements. To optimize process and result quality, priorities are in the fields of medical fundamentals of trauma care, education, and fault management. SOPs and training courses increase the process and result quality in the treatment of the trauma patient in the emergency room. These programs should be based on the special demands of the physiology of the trauma as well as the structural specifics of the hospital. ATLS does not equal an SOP but it qualifies as a standardized concept for management of trauma patients in the emergency room.

  11. 基于调度倒闸操作流程及标准操作程序的操作安全防误应用%Safety Mistake Preventing Application of Dispatching Operation Based on Scheduling Switching Operation Procedures and Standard Operating Procedures

    Institute of Scientific and Technical Information of China (English)

    樊启俊; 胡伟; 王兴存; 刘军

    2015-01-01

    An analysis is made of the dispatching operation business security mistake prevention management specification requirements and the current mainstream development mode of security anti-false application.It is proposed that the relevant anti-error safety application mode of anti-fault security check be called in different links of the procedures with the scheduling of switching operation procedures and the standard operation procedure (SOP) as the main line.And a detailed description of specific design and implementation is presented.The anti-error management of SOP is seamlessly blended with anti-false technology such as safety checking and calculation,realizing the anti-error safety of the whole procedure of dispatching operation business.%分析了调度操作业务安全防误管理的规范要求和当前主流的安全防误应用建设模式,提出了以调度倒闸操作流程及标准操作程序(SOP)为主线,在流程的不同环节调用相关安全防误校核的安全防误应用模式,并详细阐述了具体设计实现,将 SOP 的管理防误与安全校核计算等技术防误无缝融合,实现了调度操作业务的全过程安全防误。

  12. Disinfection of aircraft : Appropriate disinfectants and standard operating procedures for highly infectious diseases.

    Science.gov (United States)

    Klaus, Joachim; Gnirs, Peter; Hölterhoff, Sabine; Wirtz, Angela; Jeglitza, Matthias; Gaber, Walter; Gottschalk, Rene

    2016-12-01

    For infectious diseases caused by highly pathogenic agents (e. g., Ebola/Lassa fever virus, SARS-/MERS-CoV, pandemic influenza virus) which have the potential to spread over several continents within only a few days, international Health Protection Authorities have taken appropriate measures to limit the consequences of a possible spread. A crucial point in this context is the disinfection of an aircraft that had a passenger on board who is suspected of being infected with one of the mentioned diseases. Although, basic advice on hygiene and sanitation on board an aircraft is given by the World Health Organization, these guidelines lack details on available and effective substances as well as standardized operating procedures (SOP). The purpose of this paper is to give guidance on the choice of substances that were tested by a laboratory of Lufthansa Technik and found compatible with aircraft components, as well as to describe procedures which ensure a safe and efficient disinfection of civil aircrafts. This guidance and the additional SOPs are made public and are available as mentioned in this paper.

  13. Standard Operating Procedures and Field Methods Used for Conducting Ecological Risk Assessment Case Studies. Naval Construction Battalion Center, Davisville, Rhode Island, and Naval Shipyard, Portsmouth, Kittery, Maine.

    Science.gov (United States)

    1992-05-01

    360 JEL SOP 1.03 Revision 0 UNH, JEL Standard Operating Procedure Seaweed Collection and Population...Nitex plankton netting (500ism) - 400 in - Bronze quick-snap swivel (3.25 in.) - High-impact trawl floats (8 in.) - Hot-dip galvanized chain (0.25...different cleaning frequencies are employed and plotted against phytoplankton numbers. The frequency at which the microcosm plankton community is most

  14. STUDY OF STANDARD OPERATING PROCEDURE OF NAAG BHASMA IN RELATION TO ITS PHYSICO-CHEMICAL PROPERTIES

    Directory of Open Access Journals (Sweden)

    Lagad C. E.

    2012-03-01

    Full Text Available Standard operating procedures (SOPs should to be designed, implemented and set for all Ayurvedic drugs one by one for globalization Ayurveda. In this study, an attempt has been made to introduce SOP for preparation of Naag Bhasma [NB] & its analytical study. Study was conducted in the Department of Rasa Shastra under the postgraduate research programme is being presented. The pharmaceutical processing of NB was performed by following Samanya Shodhana, Jarana, Marana of Naag [Pb] & its analytical study. Naga Bhasma was prepared in two batches namely Batch A & B. In this method purified Haratala (Orpiment were taken as media. The percentage loss in the Naga Bhasma in Batch A was 63%, while in case of Batch B was 60.5%. Raw drugs, in process materials and the final products were analyzed physico-chemically and comparison was drawn to lay down pharmacopoeial standards. The average percentage purity of Naga decreased from 99.46% to 86.57% after Shodhana. The percentage of (Pb lead in Naga Bhasma was 58.4% and 57.89% respectively in Batch A and B. Both the Bhasmas were in PbS form chemically with other elements like Ca, Si, Fe, Al, K, As, Mg, Ni, Mn, Cd, Zn in trace amount.

  15. SAFE-P: System for Assurance of Flight Executable Procedures Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Problem: Ensuring that command execution scripts do not deviate from Standard Operating Procedures (SOPs) is time-consuming, costly, and error-prone. Deviations can...

  16. Electronic Procedures for Medical Operations Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Electronic procedures are currently being used to document the steps in performing medical operations for the Space Shuttle and/or the International Space Station...

  17. Application of SOP Model in Enterprise Logistic Operation%SOP模型在企业物流运作中的应用初探

    Institute of Scientific and Technical Information of China (English)

    陈华

    2010-01-01

    标准操作流程(SOP)对企业改善业务流程,提高物流业务的运作效率和效果,具有非常重要的意义.以基于时间的流程分析,探讨SOP模型在物流运作中的应用,并以某物流企业储运业务流程为实例,对SOP模型在企业中的实际应用进行分析.

  18. Operator use of procedures during simulated emergencies

    Energy Technology Data Exchange (ETDEWEB)

    Roth, E.M.; Mumaw, R.J.; Lewis, P.M.

    1995-04-01

    This paper summarizes the results of an empirical study of nuclear power plant operator performance in cognitively demanding simulated emergencies. During emergencies operators follow highly prescriptive written procedures. The objectives of the study were to understand and document what role higher-level cognitive activities such as diagnosis, or more generally {open_quotes}situation assessment,{close_quotes} play in guiding operator performance, given that operators utilize procedures in responding to the events. The study examined crew performance in variants of two simulated emergencies: (1) an Interfacing System Loss of Coolant Accident and (2) a Loss of Heat Sink scenario. Data on operator performance were collected using training simulators at two plant sites. Up to 11 crews from each plant participated in each of two simulated emergencies for a total of 38 cases analyzed. Crew performance was videotaped and partial transcripts were produced and analyzed. The results revealed a number of instances where higher-level cognitive activities such as situation assessment and response planning enabled operators to handle aspects of the situation that were not fully addressed by the procedures. The paper summarizes these cases and their implications for the development and evaluation of training and control room aids, as well as for human reliability analyses. The full report of the study is published as NUREG/CR-6208.

  19. 49 CFR 193.2503 - Operating procedures.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Operating procedures. 193.2503 Section 193.2503 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY LIQUEFIED NATURAL GAS FACILITIES...

  20. Standard Operating Procedures, ethical and legal regulations in BTB (Brain/Tissue/Bio) banking: what is still missing?

    Science.gov (United States)

    Ravid, Rivka

    2008-09-01

    The use of human biological specimens in scientific research is the focus of current international public and professional concern and a major issue in bioethics in general. Brain/Tissue/Bio banks (BTB-banks) are a rapid developing sector; each of these banks acts locally as a steering unit for the establishment of the local Standard Operating Procedures (SOPs) and the legal regulations and ethical guidelines to be followed in the procurement and dissemination of research specimens. An appropriat Code of Conduct is crucial to a successful operation of the banks and the research application they handle. What are we still missing ? (1) Adequate funding for research BTB-banks. (2) Standard evaluation protocls for audit of BTB-bank performance. (3) Internationally accepted SOP's which will facilitate exchange and sharing of specimens and data with the scientific community. (4) Internationally accepted Code of Conduct. In the present paper we review the most pressing organizational, methodological, medico-legal and ethical issues involved in BTB-banking; funding, auditing, procurement, management/handling, dissemination and sharing of specimens, confidentiality and data protection, genetic testing, "financial gain" and safety measures. Taking into consideration the huge variety of the specimens stored in different repositories and the enormous differences in medico-legal systems and ethics regulations in different countries it is strongly recommend that the health-care systems and institutions who host BTB-Banks will put more efforts in getting adequate funding for the infrastructure and daily activities. The BTB-banks should define evaluation protocols, SOPs and their Code of Conduct. This in turn will enable the banks to share the collected specimens and data with the largest possible number of researchers and aim at a maximal scientific spin-off and advance in public health research.

  1. Sexual Desire and Hypoactive Sexual Desire Disorder in Women. Introduction and Overview. Standard Operating Procedure (SOP Part 1)

    DEFF Research Database (Denmark)

    Bitzer, Johannes; Giraldi, Annamaria; Pfaus, Jim

    2012-01-01

    , and hormones, and psychological factors like life events, sexual biography, affective state, etc., as well as interpersonal factors like partner satisfaction, communication, duration of the relationship, and sociocultural factors interact with each other and contribute to the individual experience of desire......Introduction.  Hypoactive sexual desire disorder (HSDD) is defined in Diagnostic and Statistical Manual of Mental Disorders Fourth Edition as persistent or recurrent deficiency (or absence) of sexual fantasies/thoughts, and/or desire for or receptivity to sexual activity, which causes personal...... distress. As a largely subjective experience, sexual desire may or may not be accompanied by externally observable changes in sexual behavior. Aim.  Describe the models of understanding HSDD and the contributing factors to provide the basis for a diagnostic interview and guidance for care for healthcare...

  2. Standard operating procedures approach for the implementation of the evidence-based dentistry concept in dental practice.

    Science.gov (United States)

    Faggion, Clóvis M; Tu, Yu-Kang

    2007-09-01

    Evidence-based dentistry is a concept that when applied to clinical practice may improve the quality of dental treatment. However, dentists' reluctance to change their behavior may be a barrier to the implementation of the process. The main purpose of this study was to demonstrate that standard operating procedures (SOPs) may help dentists to apply scientific evidence to their dental practice. SOPs are written instructions on how to execute some specific tasks. A flowchart model demonstrated how an ordinary clinical procedure (composite restoration) can be performed using evidence-based information to support each executed step. Implementing the model into daily practice is straightforward, and the results are accessible to the whole dental team. In addition, the flowchart can be regularly updated with high-quality dental literature such as systematic reviews of randomized controlled trials and randomized controlled trials. This proposed model may help to bridge the gap between research and clinical dental practice by serving as a practical tool to improve the knowledge of dental practitioners and the quality of treatment.

  3. Standard operating procedures for pre-analytical handling of blood and urine for metabolomic studies and biobanks

    Energy Technology Data Exchange (ETDEWEB)

    Bernini, Patrizia; Bertini, Ivano, E-mail: bertini@cerm.unifi.it; Luchinat, Claudio [University of Florence, Magnetic Resonance Center (CERM) (Italy); Nincheri, Paola; Staderini, Samuele [FiorGen Foundation (Italy); Turano, Paola [University of Florence, Magnetic Resonance Center (CERM) (Italy)

    2011-04-15

    {sup 1}H NMR metabolic profiling of urine, serum and plasma has been used to monitor the impact of the pre-analytical steps on the sample quality and stability in order to propose standard operating procedures (SOPs) for deposition in biobanks. We analyzed the quality of serum and plasma samples as a function of the elapsed time (t = 0-4 h) between blood collection and processing and of the time from processing to freezing (up to 24 h). The stability of the urine metabolic profile over time (up to 24 h) at various storage temperatures was monitored as a function of the different pre-analytical treatments like pre-storage centrifugation, filtration, and addition of the bacteriostatic preservative sodium azide. Appreciable changes in the profiles, reflecting changes in the concentration of a number of metabolites, were detected and discussed in terms of chemical and enzymatic reactions for both blood and urine samples. Appropriate procedures for blood derivatives collection and urine preservation/storage that allow maintaining as much as possible the original metabolic profile of the fresh samples emerge, and are proposed as SOPs for biobanking.

  4. RTOD-photo operations and procedures manual

    Energy Technology Data Exchange (ETDEWEB)

    1966-03-15

    This document presents a survey of the EG&G NRDS photographic operation in four major sections and includes the work scope, procedures, some technical backgrounding and operational information. Two sections, Instrumentation and Photo Systems, include the areas of direct responsibilities while a section on Film Handling and Coordination and a section covering special information, pertinent to the project, are included to adequately complete this survey. The photographic group is housed in two trailers within the control point area at NRDS and from these trailers provides photographic support at a number of locations. Four camera bunkers, three camera towers, a kinescope system, a microfilm system and remote camera controls comprise the facilities that the group maintains and operates outside these trailers. The work load includes major items such as: motion picture coverage of the nuclear rocket engine tests, data record microfilming, kinescope recording, and documentary coverage of the company related operational responsibilities. In addition, a number of minor photographic services are extended, when required. The nature of the work, because of its importance within the research and development efforts at NRDS, requires optimum quality and efficiency throughout. The many procedures outlined here have been designed to satisfy these requirements.

  5. Raising the quality of rheumatology management recommendations: lessons from the EULAR process 10 years after provision of standard operating procedures.

    Science.gov (United States)

    Colebatch-Bourn, Alexandra N; Conaghan, Philip G; Arden, Nigel K; Cooper, Cyrus; Dougados, Maxime; Edwards, Christopher J

    2015-08-01

    To increase understanding of how to raise the quality of rheumatology guidelines by reviewing European League Against Rheumatism (EULAR) management recommendations, using the Appraisal of Guidelines for Research and Evaluation (AGREE) II instrument, 10 years after publication of the EULAR standardized operating procedures (SOP) for the production of recommendations. It was hoped that this work could help inform improvements in guideline development by other societies and organizations. The SOP were published in 2004 to ensure the quality of EULAR-endorsed recommendations. We reviewed 27 published EULAR recommendations for management using the AGREE II tool. This provides a framework to assess the quality of guidelines across six broad domains using 23 specific questions. Overall the EULAR recommendations reviewed have been performed to a high standard. There are particular strengths in the methodology and presentation of the guidelines; however, the results indicate areas for development in future recommendations: in particular, stakeholder involvement and applicability of the recommendations. Improvements in quality were evident in recent years, with patient representation in 9 of 15 (60.0%) recommendations published 2010-14 compared with 4 of 12 (33.3%) published 2000-09. In the last 10 years the overall quality of recommendations was good, with standards improving over the decade following publication of the SOP. However, this review process has identified potential areas for improvement, especially in patient representation and provision of implementation tools. The lessons from this work can be applied to the development of rheumatology guidelines by other societies and organizations. © The Author 2015. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  6. Rapid Identification and Drug Susceptibility Testing of Mycobacterium tuberculosis: Standard Operating Procedure for Non-Commercial Assays: Part 2: Nitrate Reductase Assay v1.3.12

    Directory of Open Access Journals (Sweden)

    Sarman Singh

    2012-01-01

    Full Text Available In the previous part, we presented the standard operating procedure (SOP of the microscopic observation drug susceptibility assay drug susceptibility testing (DST for Mycobacterium tuberculosis. The present SOP is devoted to another non-commercial culture and DST method known as nitrate reductase assay (NRA. As the name implies, the NRA detects the ability of M. tuberculosis to reduce nitrate to nitrite. In the assay, the presence of nitrite is detected by the addition of p-nitrobenzoate into the growth yield. The reaction is detected by the naked eye. The incorporation of drugs in the medium allows to use the test for DST, which can be interpreted with naked eyes. The identification and drug susceptibility results can be obtained in 2-3 weeks. This SOP document has been developed through the culture and DST subgroup of the STOP tuberculosis (TB Partnership New Diagnostic Working Group. It is intended for laboratories that would want to use or already using this rapid non-commercial method for culture identification and DST of M. tuberculosis, notably in resource-constraint settings in Asia and Africa.

  7. A standard operating procedure for the surgical implantation of transmitters in juvenile salmonids

    Science.gov (United States)

    Liedtke, T.L.; Beeman, J.W.; Gee, L.P.

    2012-01-01

    Biotelemetry is a useful tool to monitor the movements of animals and is widely applied in fisheries research. Radio or acoustic technology can be used, depending on the study design and the environmental conditions in the study area. A broad definition of telemetry also includes the use of Passive Integrated Transponder (PIT) tags, either separately or with a radio or acoustic transmitter. To use telemetry, fish must be equipped with a transmitter. Although there are several attachment procedures available, surgical implantation of transmitters in the abdominal cavity is recognized as the best technique for long-term telemetry studies in general (Stasko and Pincock, 1977; Winter, 1996; Jepsen, 2003), and specifically for juvenile salmonids, Oncorhynchus spp. (Adams and others, 1998a, 1998b; Martinelli and others, 1998; Hall and others, 2009). Studies that use telemetry assume that the processes by which the animals are captured, handled, and tagged, as well as the act of carrying the transmitter, will have minimal effect on their behavior and performance. This assumption, commonly stated as a lack of transmitter effects, must be valid if telemetry studies are to describe accurately the movements and behavior of an entire population of interest, rather than the subset of that population that carries transmitters. This document describes a standard operating procedure (SOP) for surgical implantation of radio or acoustic transmitters in juvenile salmonids. The procedures were developed from a broad base of published information, laboratory experiments, and practical experience in tagging thousands of fish for numerous studies of juvenile salmon movements near Columbia River and Snake River hydroelectric dams. Staff from the Western Fisheries Research Center's Columbia River Research Laboratory (CRRL) frequently have used telemetry studies to evaluate new structures or operations at hydroelectric dams in the Columbia River Basin, and these evaluations typically

  8. 40 CFR 792.81 - Standard operating procedures.

    Science.gov (United States)

    2010-07-01

    ... operating procedures. (a) A testing facility shall have standard operating procedures in writing, setting... in established standard operating procedures shall be properly authorized in writing by management... relative to the laboratory or field procedures being performed. Published literature may be used as a...

  9. 40 CFR 160.81 - Standard operating procedures.

    Science.gov (United States)

    2010-07-01

    .... (a) A testing facility shall have standard operating procedures in writing setting forth study... standard operating procedures shall be properly authorized in writing by management. (b) Standard operating... field procedures being performed. Published literature may be used as a supplement to standard operating...

  10. 46 CFR 130.480 - Test procedure and operations manual.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Test procedure and operations manual. 130.480 Section....480 Test procedure and operations manual. (a) A procedure for tests to be conducted on automated... detailed operations manual that describes the operation and indicates the location of each system...

  11. Insight into F plasmid DNA segregation revealed by structures of SopB and SopB–DNA complexes

    OpenAIRE

    2010-01-01

    Accurate DNA segregation is essential for genome transmission. Segregation of the prototypical F plasmid requires the centromere-binding protein SopB, the NTPase SopA and the sopC centromere. SopB displays an intriguing range of DNA-binding properties essential for partition; it binds sopC to form a partition complex, which recruits SopA, and it also coats DNA to prevent non-specific SopA–DNA interactions, which inhibits SopA polymerization. To understand the myriad functions of SopB, we dete...

  12. qPCR standard operating procedure for measuring microorganisms in dust from dwellings in large cohort studies.

    Science.gov (United States)

    Scherer, Emeline; Rocchi, Steffi; Reboux, Gabriel; Vandentorren, Stéphanie; Roussel, Sandrine; Vacheyrou, Mallory; Raherison, Chantal; Millon, Laurence

    2014-01-01

    The aim of the present study was to assess performance, feasibility and relevance of a Standard Operational Procedure (SOP) for large-scale use in the microbial analysis of children's indoor environments. We analyzed dust settled on Electrostatic Dust Fall Collectors (EDCs) by using qPCR which targeted 6 molds, 3 bacteria and 1 mite, chosen for their involvement in allergic or inflammatory processes. Six types of commercialized electrostatic wipes were tested for their releasing capacity of fungal DNA from fungal spores captured by the wipes. Specificity, repeatability and detection limits of the qPCR procedure were tested using calibrated microbial suspensions. The feasibility and relevance of this sampling and analysis method were assessed in a 75-home pilot study. Our result showed that one specific make of wipe was more effective than the others in releasing fungal DNA. qPCR procedure showed good repeatability. The quantification limit was about 5 fg DNA/μL for all species except Penicillium chrysogenum (0.5 fg DNA/μL) and Dermatophagoïdes pteronyssinus (10 fg DNA/μL). No cross-reactivity was observed. DNA concentrations in the 53/75 homes participating in the pilot study were between 0 and 24 625, 0 and 69 738 equivalent cells per cm(2) for the fungi and bacteria, and between 0 and 1 equivalent mites per cm(2) for D. pteronyssinus. Using the SOP described, we were able to classify the 53 dwellings from the least to the most contaminated according to the quantity of DNA measured for each species. Our SOP measured fungi, bacteria and mites using a cost-efficient, discreet and well-accepted sampling method with just one qPCR tool. The whole procedure can be used for microbial analysis in large cohort studies such as the ELFE study ("Etude Longitudinale Française depuis l'Enfance") and could help improve our understanding of the interactions between the environment, allergic diseases and child development.

  13. 21 CFR 120.6 - Sanitation standard operating procedures.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Sanitation standard operating procedures. 120.6... Provisions § 120.6 Sanitation standard operating procedures. (a) Sanitation controls. Each processor shall have and implement a sanitation standard operating procedure (SSOP) that addresses...

  14. Electronic Procedures for Medical Operations Project

    Data.gov (United States)

    National Aeronautics and Space Administration — We propose an alternative to using Microsoft Word for representing medical procedures that will make the procedures easier to construct and maintain, particularly...

  15. Managing Operating Procedures in Distributed Collaborative Projects

    Science.gov (United States)

    Hool, A.; Beuzelin Ollivier, M.-G.; Roubert, F.

    2013-04-01

    In recent years, large distributed collaborative projects have become very prominent in scientific research, allowing exchanges between laboratories located in different institutions and countries and between various domains of competence. Particularly the work on nanotoxicity - a field which has only been under investigation for a few years and is still lacking regulatory framework - highlighted the need for well-controlled methods, as well as rules for the handling and disposal of used materials. To obtain comparable and reproducible results of experiments conducted in a distributed context, the standardisation and proper documentation of the applied methods is crucial. The European project NanoDiaRA, whose aim is to develop nanoparticles and biomarkers for the early diagnosis of inflammatory disease, faces this situation as it involves 15 European partners and brings together different scientific cultures and professional backgrounds. Protocols especially developed for Superparamagnetic Iron Oxide Nanoparticles and a management system were designed and implemented within the NanoDiaRA project to fulfil those needs. The main goals were the establishment of standardised Standard Operating Procedures assuring transparency and reproducibility and the provision of access to these protocols to every project partner, as well as their clear allocation to carry out precise measurements and production steps.

  16. Preliminary Guidelines and Standard Operating Procedure for Drainage and Erosion Control at McMurdo Station

    Science.gov (United States)

    2014-12-01

    NSF National Science Foundation O&M Operations and Maintenance PAH Polycyclic Aromatic Hydrocarbons PLR Division of Polar Programs SOP Standard...merges downstream into WQB. Sub-basin 5 drains the area around the dorm, along the road towards the bay, and below the Wa- ter Treatment Plant . Sub...included heavy metals, polycyclic aromatic hydrocarbons ( PAHs ), total hydrocarbons, and volatile organic compounds. Sources of these contaminants are

  17. Optimized Standard Operating Procedures for the Analysis of Cerebrospinal Fluid Aβ42 and the Ratios of Aβ Isoforms Using Low Protein Binding Tubes

    Science.gov (United States)

    Vanderstichele, Hugo Marcel Johan; Janelidze, Shorena; Demeyer, Leentje; Coart, Els; Stoops, Erik; Herbst, Victor; Mauroo, Kimberley; Brix, Britta; Hansson, Oskar

    2016-01-01

    Background: Reduced cerebrospinal fluid (CSF) concentration of amyloid-β1-42 (Aβ1-42) reflects the presence of amyloidopathy in brains of subjects with Alzheimer’s disease (AD). Objective: To qualify the use of Aβ1-42/Aβ1-40 for improvement of standard operating procedures (SOP) for measurement of CSF Aβ with a focus on CSF collection, storage, and analysis. Methods: Euroimmun ELISAs for CSF Aβ isoforms were used to set up a SOP with respect to recipient properties (low binding, polypropylene), volume of tubes, freeze/thaw cycles, addition of detergents (Triton X-100, Tween-20) in collection or storage tubes or during CSF analysis. Data were analyzed with linear repeated measures and mixed effects models. Results: Optimization of CSF analysis included a pre-wash of recipients (e.g., tubes, 96-well plates) before sample analysis. Using the Aβ1-42/Aβ1-40 ratio, in contrast to Aβ1-42, eliminated effects of tube type, additional freeze/thaw cycles, or effect of CSF volumes for polypropylene storage tubes. ‘Low binding’ tubes reduced the loss of Aβ when aliquoting CSF or in function of additional freeze/thaw cycles. Addition of detergent in CSF collection tubes resulted in an almost complete absence of variation in function of collection procedures, but affected the concentration of Aβ isoforms in the immunoassay. Conclusion: The ratio of Aβ1-42/Aβ1-40 is a more robust biomarker than Aβ1-42 toward (pre-) analytical interfering factors. Further, ‘low binding’ recipients and addition of detergent in collection tubes are able to remove effects of SOP-related confounding factors. Integration of the Aβ1-42/Aβ1-40 ratio and ‘low-binding tubes’ into guidance criteria may speed up worldwide standardization of CSF biomarker analysis. PMID:27258423

  18. From SOPs to Reports to Evaluations: Learning and Memory ...

    Science.gov (United States)

    In an era of global trade and regulatory cooperation, consistent and scientifically based interpretation of developmental neurotoxicity (DNT) studies is essential. Because there is flexibility in the selection of test method(s), consistency can be especially challenging for learning and memory tests required by EPA and OECD DNT guidelines (chemicals and pesticides) and recommended for ICH prenatal/postnatal guidelines (pharmaceuticals). A well­ reasoned uniform approach is particularly important for variable endpoints and if non-standard tests are used. An understanding of the purpose behind the tests and expected outcomes is critical, and attention to elements of experimental design, conduct, and reporting can improve study design by the investigator as well as accuracy and consistency of interpretation by evaluators. This understanding also directs which information must be clearly described in study reports. While missing information may be available in standardized operating procedures (SOPs), if not clearly reflected in report submissions there may be questions and misunderstandings by evaluators which could impact risk assessments. A practical example will be presented to provide insights into important variables and reporting approaches. Cognitive functions most often tested in guidelines studies include associative, positional, sequential, and spatial learning and memory in weanling and adult animals. These complex behaviors tap different bra

  19. Military Publications, Index of Test Operations Procedures

    Science.gov (United States)

    1981-10-01

    checkout equipmerit subtest and an MBGC assembly operacion subtest. Static performance subtests determine accuracy, sensitivity, dead band, drift, cross...opera- tional and functional -erformaice characteristics. Discusses preliminary operacions , facilities, and equipment required. Proviies procedures for

  20. 9 CFR 416.12 - Development of Sanitation SOP's.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Development of Sanitation SOP's. 416... ACT SANITATION § 416.12 Development of Sanitation SOP's. (a) The Sanitation SOP's shall describe all... direct contamination or adulteration of product(s). (b) The Sanitation SOP's shall be signed and dated...

  1. Emergency Support Function 15 Standard Operating Procedures

    Science.gov (United States)

    2013-08-01

    pharmaceutical countermeasures, such as potassium iodide (KI). It also includes advice on long-term measures, such as restriction of food, temporary...procedures, weapon recovery, stabilization and packaging for final disposition) 3.3 Technical support requirements (attribution, weapons effects...controlled monitoring and assessment data to the lead Federal agency involved in the incident response. Once the immediate emergency is stabilized , DOE

  2. Braking, Wheeled Vehicles. Test Operations Procedure (TOP)

    Science.gov (United States)

    2008-05-20

    shields removed, inspect the internal brake components, perform a camshaft rotation test and record the measurement obtained. c. If with non-removable...preceding 24 months, perform a camshaft rotation test and record the measurement. (2) When proof of wheel removal is not provided, remove brake drum(s...adjustment. Reject the vehicle if: • The adjustment is not within the manufacturer’s specifications. 15. Brake Camshafts Procedure: With

  3. Standard operating procedures for collection of soil and sediment samples for the Sediment-bound Contaminant Resiliency and Response (SCoRR) strategy pilot study

    Science.gov (United States)

    Fisher, Shawn C.; Reilly, Timothy J.; Jones, Daniel K.; Benzel, William M.; Griffin, Dale W.; Loftin, Keith A.; Iwanowicz, Luke R.; Cohl, Jonathan A.

    2015-12-17

    An understanding of the effects on human and ecological health brought by major coastal storms or flooding events is typically limited because of a lack of regionally consistent baseline and trends data in locations proximal to potential contaminant sources and mitigation activities, sensitive ecosystems, and recreational facilities where exposures are probable. In an attempt to close this gap, the U.S. Geological Survey (USGS) has implemented the Sediment-bound Contaminant Resiliency and Response (SCoRR) strategy pilot study to collect regional sediment-quality data prior to and in response to future coastal storms. The standard operating procedure (SOP) detailed in this document serves as the sample-collection protocol for the SCoRR strategy by providing step-by-step instructions for site preparation, sample collection and processing, and shipping of soil and surficial sediment (for example, bed sediment, marsh sediment, or beach material). The objectives of the SCoRR strategy pilot study are (1) to create a baseline of soil-, sand-, marsh sediment-, and bed-sediment-quality data from sites located in the coastal counties from Maine to Virginia based on their potential risk of being contaminated in the event of a major coastal storm or flooding (defined as Resiliency mode); and (2) respond to major coastal storms and flooding by reoccupying select baseline sites and sampling within days of the event (defined as Response mode). For both modes, samples are collected in a consistent manner to minimize bias and maximize quality control by ensuring that all sampling personnel across the region collect, document, and process soil and sediment samples following the procedures outlined in this SOP. Samples are analyzed using four USGS-developed screening methods—inorganic geochemistry, organic geochemistry, pathogens, and biological assays—which are also outlined in this SOP. Because the SCoRR strategy employs a multi-metric approach for sample analyses, this

  4. Design procedure for optimizing CMOS low noise operational amplifiers

    Institute of Scientific and Technical Information of China (English)

    Li Zhiyuan; Ye Yizheng; Ma Jianguo

    2009-01-01

    This paper presents and experimentally verifies an optimized design procedure for a CMOS low noise operational amplifier.The design procedure focuses on the noise performance,which is the key requirement for low noise operational amplifiers.Based on the noise level and other specifications such as bandwidth,signal swing,slew rate,and power consumption,the device sizes and the biasing conditions are derived.In order to verify the proposed design procedure,a three-stage operational amplifier has been designed.The device parameters obtained from the proposed design procedure closely agree with the simulated results obtained by using HSPICE.

  5. Partition of the Linear Plasmid N15: Interactions of N15 Partition Functions with the sop Locus of the F Plasmid

    OpenAIRE

    1999-01-01

    A locus close to one end of the linear N15 prophage closely resembles the sop operon which governs partition of the F plasmid; the promoter region contains similar operator sites, and the two putative gene products have extensive amino acid identity with the SopA and -B proteins of F. Our aim was to ascertain whether the N15 sop homologue functions in partition, to identify the centromere site, and to examine possible interchangeability of function with the F Sop system. When expressed at a m...

  6. Operator coil monitoring Acceptance Test Procedure

    Energy Technology Data Exchange (ETDEWEB)

    Erhart, M.F.

    1995-05-16

    The readiness of the Data Acquisition and Control System (DACS) to provide monitoring and control of the Programmable Logic Controller (PLC) abort coils from the Master and RSS stations will be systematically tested during performance of this procedure. It should be noted that these are not physical abort coils but software coils controlled by the software`s ladder logic. The readiness of the DACS to properly interface with the ENRAF wire level gauge installed in the SY-101 storage tank will also be tested. During this test, a verification of all abort coil indications will be conducted at the DACS Development Facility in the 306E Building by injecting an input signal for each DACS sensor that has an associated abort coil until the abort coil actuates, and then ensuring that the status of the abort coil indicated at the Master and RSS stations is correct. Each abort coil will also be tested to ensure that the ``ENABLE`` and ``DISABLE`` controls from the Master and RSS stations function correctly, and only with the use of proper passwords.

  7. Vector operations for modelling data-conversion procedures

    Energy Technology Data Exchange (ETDEWEB)

    Rivkin, M.N.

    1992-03-01

    This article presents a set of vector operations that permit effective modelling of operations from extended relational algebra for implementations of variable-construction procedures in data-conversion processors. Vector operations are classified, and test results are given for the ARIUS UP and other popular database management systems for PC`s. 10 refs., 5 figs.

  8. 美国EPA最新发布农药对居住者健康的风险评估方法%New standard operating procedures for residential pesticide exposure assessment of EPA

    Institute of Scientific and Technical Information of China (English)

    王以燕

    2013-01-01

    2012年10月,美国环境保护局发布了第二版农药对居住者的风险评估方法准则(Standard Operating Procedure 2012)(简称:最新EPA-SOP),笔者主要介绍评估室内卫生用农药的部分.由于部分内容仅适用美国的情况,我国如何评估室内卫生用农药产品,还需探讨和研究.

  9. A critical investigation of dangerous goods procedures in logistics operations.

    OpenAIRE

    Wojtczuk, Kamil

    2012-01-01

    University of Nottingham “A critical investigation of dangerous goods procedures in logistics operations.” Kamil Wojtczuk MSc Logistics and Supply Chain Management   “A critical investigation of dangerous goods procedures in logistics operations.” by Kamil Wojtczuk 2011   Summary of dissertation This dissertation comprises five chapters and three appendixes. The dissertation starts with an introduction where all research objectives are placed. In the first...

  10. The operational procedure of an electron beam accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Byung Cheol; Choi, Hwa Lim; Yang, Ki Ho; Han, Young Hwan; Kim, Sung Chan

    2008-12-15

    The KAERI(Korea Atomic Energy of Research Institute) high-power electron beam irradiation facility, operating at the energies between 0.3 MeV and 10 MeV, has provided irradiation services to users in industries, universities, and institute in various fields. This manual is for the operation of an electron beam which is established in KAERI, and describes elementary operation procedures of electron beam between 0.3 Mev and 10 MeV. KAERI Electron Accelerator facility(Daejeon, Korea) consists of two irradiators: one is a low-energy electron beam irradiator operated by normal conducting RF accelerator, the other is medium-energy irradiator operated by superconducting RF accelerator. We explain the check points of prior to operation, operation procedure of this facility and the essential parts of electron beam accelerator.

  11. Safety and emergency preparedness considerations for geotechnical field operations

    Energy Technology Data Exchange (ETDEWEB)

    Wemple, R.P.

    1989-04-01

    The GEO Energy Technology Department at Sandia National Laboratories is involved in several remote-site drilling and/or experimental operations each year. In 1987, the Geothermal Research Division of the Department developed a general set of Safe Operating Procedures (SOPs) that could be applied to a variety of projects. This general set is supplemented by site-specific SOPs as needed. Effective field operations require: integration of safety and emergency preparedness planning with overall project planning, training of field personnel and inventorying of local emergency support resources, and, developing a clear line of responsibility and authority to enforce the safety requirements. Copies of SOPs used in recent operations are included as examples of working documents for the reader.

  12. Analytical Chemistry Laboratory (ACL) procedure compendium. Volume 7, Safety operation procedure for hot cell

    Energy Technology Data Exchange (ETDEWEB)

    1993-08-01

    This volume contains the interim change notice for the safety operation procedure for hot cell. It covers the master-slave manipulators, dry waste removal, cell transfers, hoists, cask handling, liquid waste system, and physical characterization of fluids.

  13. SipA, SopA, SopB, SopD, and SopE2 Contribute to Salmonella enterica Serotype Typhimurium Invasion of Epithelial Cells

    OpenAIRE

    2005-01-01

    The centisome 63 type III secretion system (T3SS-1) encoded by Salmonella pathogenicity island 1 (SPI1) mediates invasion of epithelial cells by Salmonella enterica serotype Typhimurium. Characterization of mutants lacking individual genes has revealed that T3SS-1 secreted proteins (effectors) SopE2 and SopB are required for invasion while the SipA protein accelerates entry into cells. Here we have revisited the question of which T3SS-1 effectors contribute to the invasion of epithelial cells...

  14. Environmental Quality Information Analysis Center (EQIAC) operating procedures handbook

    Energy Technology Data Exchange (ETDEWEB)

    Walsh, T.E. (Florida Univ., Gainesville, FL (United States)); Das, S. (Oak Ridge National Lab., TN (United States))

    1992-08-01

    The Operating Procedures Handbook of the Environmental Quality Information Analysis Center (EQIAC) is intended to be kept current as EQIAC develops and evolves. Its purpose is to provide a comprehensive guide to the mission, infrastructure, functions, and operational procedures of EQIAC. The handbook is a training tool for new personnel and a reference manual for existing personnel. The handbook will be distributed throughout EQIAC and maintained in binders containing current dated editions of the individual sections. The handbook will be revised at least annually to reflect the current structure and operational procedures of EQIAC. The EQIAC provides information on environmental issues such as compliance, restoration, and environmental monitoring do the Air Force and DOD contractors.

  15. Fabricating an S&OP Process

    DEFF Research Database (Denmark)

    Lichen, Alex Yu

    Inspired by Latour’s (2005a) notion of matters of concern and M.C. Escher’s Circle Limit III as a representation of the Poincaré Disk, this study follows how an S&OP process was fabricated in a large Swedish manufacturing company. The study claims that when actors are fabricating the S&OP process......, local actors create emergent, ongoing and multiple matters of concern around it. The group demand chain, the actor who is responsible for guiding the implementation of the process, delegates the attempts to close these matters of concern to local actors located in separate times and spaces. As a result......, constituents of the S&OP process are dispersed in diverse local times and spaces rather than being coordinated in a single time and space by the group demand chain. Accounting is a set of matters of concern. The S&OP process and its purpose of integration come from an “absolute nothingness” – its minimal...

  16. ARM Operations and Engineering Procedure Mobile Facility Site Startup

    Energy Technology Data Exchange (ETDEWEB)

    Voyles, Jimmy W

    2015-05-01

    This procedure exists to define the key milestones, necessary steps, and process rules required to commission and operate an Atmospheric Radiation Measurement (ARM) Mobile Facility (AMF), with a specific focus toward on-time product delivery to the ARM Data Archive. The overall objective is to have the physical infrastructure, networking and communications, and instrument calibration, grooming, and alignment (CG&A) completed with data products available from the ARM Data Archive by the Operational Start Date milestone.

  17. Deep Attack Map Exercise (DAME) Game Rules and Operating Procedures

    Science.gov (United States)

    1983-02-01

    wargame for use in the Close Combat (Heavy) Mission Area Analysis. Using a map board, a set of computer algorithms , and manual rules, the wargame...logistics, and command and control. This report documents the rules, operating procedures, and computer algorithms which were used in the map game. The

  18. 14 CFR 93.71 - General operating procedures.

    Science.gov (United States)

    2010-01-01

    ... of Niagara Falls, New York § 93.71 General operating procedures. (a) Flight restrictions are in effect below 3,500 feet MSL in the airspace above Niagara Falls, New York, west of a line from latitude... orbit of the Niagara Falls area below 3,500 feet MSL over the Niagara River. (d) The minimum...

  19. Surgical site infections in paediatric otolaryngology operative procedures.

    Science.gov (United States)

    Ifeacho, S N; Bajaj, Y; Jephson, C G; Albert, D M

    2012-07-01

    An assessment of the rate of surgical site infections associated with elective paediatric otolaryngology surgical procedures. Prospective data was collected for a 3-week period for all children undergoing surgery where either mucosa or skin was breached. The parents of the children were requested to complete a questionnaire at 30 days after the operation. Data was collected on 80 consecutive cases. The majority of cases were admitted on the day of the procedure. The procedures included adenotonsillectomy (24), grommets (12), cochlear implantation (6), bone-anchored hearing aid (2), submandibular gland excision (1), branchial sinus excision (1), cystic hygroma excision (3), nasal glioma excision (1), microlaryngobronchoscopy (13), tracheostomy (3) and other procedures (14). Nearly half the cases had more than one operation done at the same time. 26/80 (32.5%) patients had a temporary or permanent implant inserted at the time of operation (grommet, bone-anchored hearing aid, cochlear implant). 25/80 (31%) operative fields were classed as clean and 55/80 (68.7%) as clean contaminated operations. The duration of the operation varied from 6 min to 142 min. Hospital antibiotic protocol was adhered to in 69/80 (86.3%) cases but not in 11/80 cases. In our series, 3/80 (3.7%) patients had an infection in the postoperative period. Surgical site infections do occur at an appreciable rate in paediatric otolaryngology. With the potential for serious consequences, reduction in the risk of surgical site infections is important. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  20. CTEPP STANDARD OPERATING PROCEDURE FOR EXTRACTING AND PREPARING AIR SAMPLES FOR ANALYSIS OF NEUTRAL PERSISTENT ORGANIC POLLUTANTS (SOP-5.12)

    Science.gov (United States)

    The method is for extracting an indoor and outdoor air sample consisting of a quartz fiber filter and an XAD-2 cartridge for analysis of neutral persistent organic pollutants. It covers the extraction and concentration of samples that are to be analyzed by gas chromatography/mass...

  1. CTEPP STANDARD OPERATING PROCEDURE FOR EXTRACTING AND PREPARING AIR SAMPLES FOR ANALYSIS OF NEUTRAL PERSISTENT ORGANIC POLLUTANTS (SOP-5.12)

    Science.gov (United States)

    The method is for extracting an indoor and outdoor air sample consisting of a quartz fiber filter and an XAD-2 cartridge for analysis of neutral persistent organic pollutants. It covers the extraction and concentration of samples that are to be analyzed by gas chromatography/mass...

  2. Reversal of Hartmann's procedure: a high-risk operation?

    Science.gov (United States)

    Schmelzer, Thomas M; Mostafa, Gamal; Norton, H James; Newcomb, William L; Hope, William W; Lincourt, Amy E; Kercher, Kent W; Kuwada, Timothy S; Gersin, Keith S; Heniford, B Todd

    2007-10-01

    Patients who undergo Hartmann's procedure often do not have their colostomy closed based on the perceived risk of the operation. This study evaluated the outcome of reversal of Hartmann's procedure based on preoperative risk factors. We retrospectively reviewed adult patients who underwent reversal of Hartmann's procedure at our tertiary referral institution. Patient outcomes were compared based on identified risk factors (age >60 years, American Society of Anesthesiologists [ASA] score >2, and >2 preoperative comorbidities). One-hundred thirteen patients were included. Forty-four patients (39%) had an ASA score of >or=3. The mean hospital duration of stay was 6.8 days. There were 28 (25%) postoperative complications and no mortality. Patients >60 years old had significantly longer LOS compared with the rest of the group (P = .02). There were no differences in outcomes between groups based on ASA score or the presence of multiple preoperative comorbidities. An albumin level of <3.5 was the only significant predictor of postoperative complications (P = .04). The reversal of Hartmann's operation appears to be a safe operation with acceptable morbidity rates and can be considered in patients, including those with significant operative risk factors.

  3. User's operating procedures. Volume 2: Scout project financial analysis program

    Science.gov (United States)

    Harris, C. G.; Haris, D. K.

    1985-01-01

    A review is presented of the user's operating procedures for the Scout Project Automatic Data system, called SPADS. SPADS is the result of the past seven years of software development on a Prime mini-computer located at the Scout Project Office, NASA Langley Research Center, Hampton, Virginia. SPADS was developed as a single entry, multiple cross-reference data management and information retrieval system for the automation of Project office tasks, including engineering, financial, managerial, and clerical support. This volume, two (2) of three (3), provides the instructions to operate the Scout Project Financial Analysis program in data retrieval and file maintenance via the user friendly menu drivers.

  4. Operative findings in recurrent hernia after a Lichtenstein procedure

    DEFF Research Database (Denmark)

    Bay-Nielsen, M; Nordin, P; Nilsson, E;

    2001-01-01

    at the pubic tubercle. METHODS: A review was made of 87 records from operations for recurrence after a previous Lichtenstein procedure, based upon national and large area data bases, recording 95% (Denmark) and 50% (Sweden) of all inguinal hernia operations. RESULTS: Direct recurrences were found in 62......%, whereas the remaining recurrences were either indirect (17%), femoral (13%), or other/unclassified (8%). CONCLUSION: The most plausible explanation for the development of the direct recurrences is an insufficient medial mesh fixation and overlap over the pubic tubercle. Avoidance of more than half...

  5. Real Interest Rates and Central Bank Operating Procedures

    OpenAIRE

    Matthew B. Canzoneri; Dellas, Harris

    1995-01-01

    In the years following the influential article of Poole (1970), many central banks reoriented their operating procedures to focus more on interest rates and less on monetary aggregates. The rapid restructuring of global financial markets was thought to have led to instability in standard monetary relationships, and Poole's basic insight suggested that a central bank would have better control of the price level if it targeted nominal interest rates instead of monetary aggregates. At the same t...

  6. An operational procedure for rapid flood risk assessment in Europe

    Science.gov (United States)

    Dottori, Francesco; Kalas, Milan; Salamon, Peter; Bianchi, Alessandra; Alfieri, Lorenzo; Feyen, Luc

    2017-07-01

    The development of methods for rapid flood mapping and risk assessment is a key step to increase the usefulness of flood early warning systems and is crucial for effective emergency response and flood impact mitigation. Currently, flood early warning systems rarely include real-time components to assess potential impacts generated by forecasted flood events. To overcome this limitation, this study describes the benchmarking of an operational procedure for rapid flood risk assessment based on predictions issued by the European Flood Awareness System (EFAS). Daily streamflow forecasts produced for major European river networks are translated into event-based flood hazard maps using a large map catalogue derived from high-resolution hydrodynamic simulations. Flood hazard maps are then combined with exposure and vulnerability information, and the impacts of the forecasted flood events are evaluated in terms of flood-prone areas, economic damage and affected population, infrastructures and cities.An extensive testing of the operational procedure has been carried out by analysing the catastrophic floods of May 2014 in Bosnia-Herzegovina, Croatia and Serbia. The reliability of the flood mapping methodology is tested against satellite-based and report-based flood extent data, while modelled estimates of economic damage and affected population are compared against ground-based estimations. Finally, we evaluate the skill of risk estimates derived from EFAS flood forecasts with different lead times and combinations of probabilistic forecasts. Results highlight the potential of the real-time operational procedure in helping emergency response and management.

  7. Treatment of ruptured Achilles tendon: Operative or non-operative procedure?

    Science.gov (United States)

    Cukelj, Fabijan; Bandalovic, Ante; Knezevic, Josip; Pavic, Arsen; Pivalica, Bozen; Bakota, Bore

    2015-11-01

    The aim of this study was to compare the efficiency of non-operative and surgical procedures in the treatment of ruptured Achilles tendon in athletes (professional and amateur). Ninety professional or amateur athletes with rupture of the Achilles tendon were included in the study between 1998 and 2013. The athletes were aged between 25 and 40 years (mean 34.83±4.65). A total of 30 athletes underwent an open procedure, 30 were treated with a percutaneous method and 30 were treated non-operatively. All operated patients were tested one year after the surgical procedure. An isokinetic dynamometer was used to compare the open and percutaneous methods. The results for the patients who were treated using the percutaneous method were 15% better than those for the patients who underwent the open procedure; the results for the group treated conservatively were 20% better than those for the group treated percutaneously. The percutaneous method was easier technically than the open method. Time spent in hospital was 14.5 times shorter with the percutaneous procedure compared with the open procedure (percutaneous procedure: range 0.5-2 days, mean 0.79±0.36; open procedure: range 10-24 days, mean 11.46±2.70; pAchilles tendon in the group treated with the percutaneous procedure. One patient in the group treated with the open procedure had postoperative infection (4.2%). In the non-surgical (conservatively treated) group, there were three reruptures of the Achilles tendon within one year, and one patient developed adhesions that resulted in loss of function and had to undergo an operation. The percutaneous method is the best method of surgical treatment for Achilles tendon rupture. Copyright © 2015 Elsevier Ltd. All rights reserved.

  8. Research on application of standard operating procedures in quality management of outpatient triage system%标准操作程序在门诊预检分诊质量管理中的应用研究

    Institute of Scientific and Technical Information of China (English)

    刘龙秀

    2012-01-01

    目的 探讨如何提高门诊预检分诊效率、准确率以及患者的满意度.方法 采用标准操作程序(SOP),制定并实施以症状为主诉的门诊预检分诊的标准问诊流程.结果 实施分诊的标准问诊流程后门诊预检分诊准确率达到96%,预检分诊正确率提高9%,与实施前比较P<0.05;预检分诊的时间缩短了6.47s(P<0.05);患者满意度达到98%,提高了10%(P<0.05).结论 SOP能提高门诊预检分诊效率及正确率.%Objective To explore the methods for improvement of the efficiency and accuracy of outpatient triage system as well as the satisfactoriness of patients. Methods Based on the standard operating procedures (SOP),We formulated and implemented a standard interrogation processes with symptoms as the chief complaint for outpatient triage system. Results After the implementation of standard interrogation processes,the accuracy rate of outpatient triage system was 96% ,which increased by 9% (P = 0.040). The time of outpatient triage system was shortened by 6. 47 seconds ( P= 0. 033). The patients ' satisfactoriness toward outpatient triage system was 98%,which increased by 10% (P = 0.010). Conclusion SOP can improve the efficiency and accuracy of outpatient triage system.

  9. Loss on Ignition Furnace Acceptance and Operability Test Procedure

    Energy Technology Data Exchange (ETDEWEB)

    JOHNSON, D.C.

    2000-06-01

    The purpose of this Acceptance Test Procedure and Operability Test Procedure (ATP/OTP)is to verify the operability of newly installed LOI equipment, including a model 1608FL CM{trademark} Furnace, a dessicator, and balance. The operability of the furnace will be verified. The arrangement of the equipment placed in Glovebox 157-3/4 to perform Loss on Ignition (LOI) testing on samples supplied from the Thermal Stabilization line will be verified. In addition to verifying proper operation of the furnace, this ATP/OTP will also verify the air flow through the filters, verify a damper setting to establish and maintain the required differential pressure between the glovebox and the room pressure, and test the integrity of the newly installed HEPA filter. In order to provide objective evidence of proper performance of the furnace, the furnace must heat 15 crucibles, mounted on a crucible rack, to 1000 C, according to a program entered into the furnace controller located outside the glovebox. The glovebox differential pressure will be set to provide the 0.5 to 2.0 inches of water (gauge) negative pressure inside the glovebox with an airflow of 100 to 125 cubic feet per minute (cfm) through the inlet filter. The glovebox inlet Glfilter will he flow tested to ensure the integrity of the filter connections and the efficiency of the filter medium. The newly installed windows and glovebox extension, as well as all disturbed joints, will be sonically tested via ultra probe to verify no leaks are present. The procedure for DOS testing of the filter is found in Appendix A.

  10. [Patient safety recommendations for out of operating room procedure sedation].

    Science.gov (United States)

    Arnal Velasco, D; Romero García, E; Martínez Palli, G; Muñoz Corsini, L; Rey Martínez, M; Postigo Morales, S

    There is an increasing and more complex demand for sedation for procedures out of the operating room. For different reasons, nowadays the administration of sedation varies considerably. We believe that a patient safety approach rather an approach out of corporate or economic interests is desirable. We created a working group of experts within the Spanish Anaesthesia and Reanimation Incident Reporting System (SENSAR) to prepare a series of recommendations through a non-systematic review. These recommendations were validated by an expert panel of 31 anaesthesiologists through two rounds of an adaptation of the Delphi Method where more than 70% agreement was required. The resulting recommendations include previous evaluation, material and staffing needs for sedation for procedures, post-sedation recommendations and activity and quality control advice. We present patient centred recommendations for the safe use of sedation for out of the operating room procedures from the point of view of the professionals with the most experience in its administration. We believe that these can be used as a guide to reduce variability and increase patient safety in the organisation of healthcare. Copyright © 2016 SECA. Publicado por Elsevier España, S.L.U. All rights reserved.

  11. Patient safety recommendations for out of operating room procedure sedation.

    Science.gov (United States)

    Arnal Velasco, D; Romero García, E; Martínez Palli, G; Muñoz Corsini, L; Rey Martínez, M; Postigo Morales, S

    2016-12-01

    There is an increasing and more complex demand for sedation for procedures out of the operating room. For different reasons, nowadays the administration of sedation varies considerably. We believe that a patient safety approach rather an approach out of corporate or economic interests is desirable. We created a working group of experts within the Spanish Anaesthesia and Reanimation Incident Reporting System (SENSAR) to prepare a series of recommendations through a non-systematic review. These recommendations were validated by an expert panel of 31 anaesthesiologists through two rounds of an adaptation of the Delphi Method where more than 70% agreement was required. The resulting recommendations include previous evaluation, material and staffing needs for sedation for procedures, post-sedation recommendations and activity and quality control advice. We present patient centred recommendations for the safe use of sedation for out of the operating room procedures from the point of view of the professionals with the most experience in its administration. We believe that these can be used as a guide to reduce variability and increase patient safety in the organisation of healthcare. Copyright © 2016 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Publicado por Elsevier España, S.L.U. All rights reserved.

  12. Identification of SopE2, a Salmonella Secreted Protein Which Is Highly Homologous to SopE and Involved in Bacterial Invasion of Epithelial Cells

    OpenAIRE

    2000-01-01

    Type III secreted Sop protein effectors are delivered into target eukaryotic cells and elicit cellular responses underlying Salmonella pathogenicity. In this work, we have identified another secreted protein, SopE2, and showed that SopE2 is an important invasion-associated effector. SopE2 is encoded by the sopE2 gene which is present and conserved in pathogenic strains of Salmonella. SopE2 is highly homologous to SopE, a protein encoded by a gene within a temperate bacteriophage and present i...

  13. Review of the IEEE Standard for Computerized Operating Procedure Systems

    Energy Technology Data Exchange (ETDEWEB)

    O' Hara, J.; Higgins, J.

    2010-02-26

    Increasingly nuclear power plant procedures, such as emergency operating procedures, are being presented in computer form with functionality to support operator use and management of the procedures. The U.S. Nuclear Regulatory Commission (NRC) currently has guidance for the review of computer-based procedures (CBPs); however, there remain CBP functions and human performance issues for which up-to-date guidance is lacking. The Institute of Electrical and Electronics Engineers (IEEE) has initiated a standard development effort to address the human factors engineering (HFE) aspects of CBP systems. When completed, it may provide guidance to supplement the NRC staff's review criteria. The purpose of our study was to evaluate the suitability of the IEEE Standard for use in the NRC's HFE safety reviews of CBP systems and to ensure that the guidance meets the NRC's standard for scientific and engineering rigor used in its own guidance development efforts. We established the following criteria with which to evaluate the Standard: (1) it should meet an existing need of NRC reviewers, (2) it should be based in sound HFE principles, (3) it should be thoroughly peer-reviewed, and (4) it should address CBP-related human performance issues identified in the literature. This report describes the methodology we used to evaluate each criterion. Our evaluation concluded that the Standard generally does meet these criteria, however several areas were identified for which additional clarifications are needed. Thus consideration of the Standard's use by the NRC is supported. The standard evaluation methodology developed in this study can be generally applied to the review of other HFE standards being considered for possible use or endorsement by the NRC.

  14. The European Stroke Organisation Guidelines: a standard operating procedure.

    Science.gov (United States)

    Ntaios, George; Bornstein, Natan M; Caso, Valeria; Christensen, Hanne; De Keyser, Jacques; Diener, Hans-Christoph; Diez-Tejedor, Exuperio; Ferro, Jose M; Ford, Gary A; Grau, Armin; Keller, Emanuella; Leys, Didier; Russell, David; Toni, Danilo; Turc, Guillaume; Van der Worp, Bart; Wahlgren, Nils; Steiner, Thorsten

    2015-10-01

    In 2008, the recently founded European Stroke Organisation published its guidelines for the management of ischemic stroke and transient ischemic attack. This highly cited document was translated in several languages and was updated in 2009. Since then, the European Stroke Organisation has published guidelines for the management of intracranial aneurysms and subarachnoidal hemorrhage, for the establishment of stroke units and stroke centers, and recently for the management of intracerebral hemorrhage. In recent years, the methodology for the development of guidelines has evolved significantly. To keep pace with this progress and driven by the strong determination of the European Stroke Organisation to further promote stroke management, education, and research, the European Stroke Organisation decided to delineate a detailed standard operating procedure for its guidelines. There are two important cornerstones in this standard operating procedure: The first is the implementation of the Grading of Recommendations Assessment, Development, and Evaluation methodology for the development of its Guideline Documents. The second one is the decision of the European Stroke Organisation to move from the classical model of a single Guideline Document about a major topic (e.g. management of ischemic stroke) to focused modules (i.e. subdivisions of a major topic). This will enable the European Stroke Organisation to react faster when new developments in a specific stroke field occur and update its recommendations on the related module rather swiftly; with the previous approach of a single large Guideline Document, its entire revision had to be completed before an updated publication, delaying the production of up-to-date guidelines. After discussion within the European Stroke Organisation Guidelines Committee and significant input from European Stroke Organisation members as well as methodologists and analysts, this document presents the official standard operating procedure for

  15. Desain dan Implementasi Standar Operasional Prosedur (SOP Keamanan Sistem Informasi Fakultas Teknik Universitas Diponegoro Menggunakan Standar ISO 27001

    Directory of Open Access Journals (Sweden)

    Penji Prasetya

    2015-08-01

    Full Text Available Like today's modern era, information technology is needed to support the business processes of the organization. In the use of information technology organization must have policies and standard operating procedures are good that any work carried out in the appropriate direction of the organization. Not only that, the organization must also pay attention to information security of any assets owned. This final project aims to make policies and standard operating procedures (SOP and assessing the information security risk in the assets of the organization. In the process of this skripsi refers to the standard of ISO 27001 as the standard for information security management and use of qualitative methodology, where qualitative methodology is a methodology that produces descriptive data in the form of words written or spoken of people and behaviors that can be observed. This final project resulted in the level of risk that is contained in the value of assets and generate recommendations to improve the security controls in the information security of assets based on the clauses of ISO 27001. In accordance with the initial objective of this final project also produce information security policy document and document information security standard operating procedures.

  16. Evaluations of Generic ABWR ATWS Emergency Operation Procedures Using MAAP

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Ying-Ting; Ferng, Yuh-Ming; Peir, Jinn-Jer; Shih, Chunkuan [Department of Engineering and System Science, National Tsing Hua University, Hsinchu, Taiwan (China)

    2008-07-01

    Lungmen NPP, the fourth one in Taiwan is under construction and the EOP (Emergency Operation Procedures) for Lungmen NPP, originally provided by GE (General Electric) is currently under review and verification. In this paper, a specific sequence of transients including LOTDRFP (Loss of Turbine Driven Feedwater Pump), ATWS (Anticipated Transients Without Scram) and LOCA (Loss of Coolant Accident) were considered in order to ensure that the operator could bring the NPP to a safe condition by following the directions of EOP in this particular transient scenario. MAAP (Modular Accident Analysis Program), version 4.05 that is fast-running while producing credible results was used for transient simulations. The results of simulation indicated that the NPP indeed could be brought to a safe condition by following the EOP. It is also found that the transient sequence would evolve into an entirely different way due to the operator's action, and the time delay between each step would greatly affect the transient sequence too. (authors)

  17. Diagnostic procedures for non-small-cell lung cancer (NSCLC): recommendations of the European Expert Group

    OpenAIRE

    Dietel, Manfred; Bubendorf, Lukas; Dingemans, Anne-Marie C; Dooms, Christophe; Elmberger, Göran; García, Rosa Calero; Keith M Kerr; Lim, Eric; López-Ríos, Fernando; Thunnissen, Erik; Van Schil, Paul E.; von Laffert, Maximilian

    2015-01-01

    Background There is currently no Europe-wide consensus on the appropriate preanalytical measures and workflow to optimise procedures for tissue-based molecular testing of non-small-cell lung cancer (NSCLC). To address this, a group of lung cancer experts (see list of authors) convened to discuss and propose standard operating procedures (SOPs) for NSCLC. Methods Based on earlier meetings and scientific expertise on lung cancer, a multidisciplinary group meeting was aligned. The aim was to inc...

  18. Quality assurance: Importance of systems and standard operating procedures.

    Science.gov (United States)

    Manghani, Kishu

    2011-01-01

    It is mandatory for sponsors of clinical trials and contract research organizations alike to establish, manage and monitor their quality control and quality assurance systems and their integral standard operating procedures and other quality documents to provide high-quality products and services to fully satisfy customer needs and expectations. Quality control and quality assurance systems together constitute the key quality systems. Quality control and quality assurance are parts of quality management. Quality control is focused on fulfilling quality requirements, whereas quality assurance is focused on providing confidence that quality requirements are fulfilled. The quality systems must be commensurate with the Company business objectives and business model. Top management commitment and its active involvement are critical in order to ensure at all times the adequacy, suitability, effectiveness and efficiency of the quality systems. Effective and efficient quality systems can promote timely registration of drugs by eliminating waste and the need for rework with overall financial and social benefits to the Company.

  19. Operating room waste: disposable supply utilization in neurosurgical procedures.

    Science.gov (United States)

    Zygourakis, Corinna C; Yoon, Seungwon; Valencia, Victoria; Boscardin, Christy; Moriates, Christopher; Gonzales, Ralph; Lawton, Michael T

    2017-02-01

    OBJECTIVE Disposable supplies constitute a large portion of operating room (OR) costs and are often left over at the end of a surgical case. Despite financial and environmental implications of such waste, there has been little evaluation of OR supply utilization. The goal of this study was to quantify the utilization of disposable supplies and the costs associated with opened but unused items (i.e., "waste") in neurosurgical procedures. METHODS Every disposable supply that was unused at the end of surgery was quantified through direct observation of 58 neurosurgical cases at the University of California, San Francisco, in August 2015. Item costs (in US dollars) were determined from the authors' supply catalog, and statistical analyses were performed. RESULTS Across 58 procedures (36 cranial, 22 spinal), the average cost of unused supplies was $653 (range $89-$3640, median $448, interquartile range $230-$810), or 13.1% of total surgical supply cost. Univariate analyses revealed that case type (cranial versus spinal), case category (vascular, tumor, functional, instrumented, and noninstrumented spine), and surgeon were important predictors of the percentage of unused surgical supply cost. Case length and years of surgical training did not affect the percentage of unused supply cost. Accounting for the different case distribution in the 58 selected cases, the authors estimate approximately $968 of OR waste per case, $242,968 per month, and $2.9 million per year, for their neurosurgical department. CONCLUSIONS This study shows a large variation and significant magnitude of OR waste in neurosurgical procedures. At the authors' institution, they recommend price transparency, education about OR waste to surgeons and nurses, preference card reviews, and clarification of supplies that should be opened versus available as needed to reduce waste.

  20. Improved Design of Crew Operation in Computerized Procedure System of APR1400

    Energy Technology Data Exchange (ETDEWEB)

    Seong, No Kyu; Jung, Yeon Sub; Sung, Chan Ho [KHNP, Daejeon (Korea, Republic of)

    2016-05-15

    The operators perform the paper-based procedures in analog-based conventional main control room (MCR) depending on only communications between operators except a procedure controller such as a Shift Supervisor (SS), however in digital-based MCR the operators can confirm the procedures simultaneously in own console when the procedure controller of computerized procedure (CP) opens the CP. The synchronization and a synchronization function between procedure controller and other operators has to be considered to support the function of crew operation. This paper suggests the improved design of crew operation in computerized procedure system of APR1400. This paper suggests the improved design of APR1400 CPS. These improvements can help operators perform the crew procedures more efficiently. And they reduce a burden of communication and misunderstanding of computerized procedures. These improvements can be applied to CPS after human factors engineering verification and validation.

  1. HEMP emergency planning and operating procedures for electric power systems

    Energy Technology Data Exchange (ETDEWEB)

    Reddoch, T.W.; Markel, L.C. (Electrotek Concepts, Inc., Knoxville, TN (United States))

    1991-01-01

    Investigations of the impact of high-altitude electromagnetic pulse (HEMP) on electric power systems and electrical equipment have revealed that HEMP creates both misoperation and failures. These events result from both the early time E[sub 1] (steep-front pulse) component and the late time E[sub 3] (geomagnetic perturbations) component of HEMP. In this report a HEMP event is viewed in terms of its marginal impact over classical power system disturbances by considering the unique properties and consequences of HEMP. This report focuses on system-wide electrical component failures and their potential consequences from HEMP. In particular, the effectiveness of planning and operating procedures for electric systems is evaluated while under the influence of HEMP. This assessment relies on published data and characterizes utilities using the North American Electric Reliability Council's regions and guidelines to model electric power system planning and operations. Key issues addressed by the report include how electric power systems are affected by HEMP and what actions electric utilities can initiate to reduce the consequences of HEMP. The report also reviews the salient features of earlier HEMP studies and projects, examines technology trends in the electric power industry which are affected by HEMP, characterizes the vulnerability of power systems to HEMP, and explores the capability of electric systems to recover from a HEMP event.

  2. HEMP emergency planning and operating procedures for electric power systems

    Energy Technology Data Exchange (ETDEWEB)

    Reddoch, T.W.; Markel, L.C. (Electrotek Concepts, Inc., Knoxville, TN (United States))

    1991-01-01

    Investigations of the impact of high-altitude electromagnetic pulse (HEMP) on electric power systems and electrical equipment have revealed that HEMP creates both misoperation and failures. These events result from both the early time E[sub 1] (steep-front pulse) component and the late time E[sub 3] (geomagnetic perturbations) component of HEMP. In this report a HEMP event is viewed in terms of its marginal impact over classical power system disturbances by considering the unique properties and consequences of HEMP. This report focuses on system-wide electrical component failures and their potential consequences from HEMP. In particular, the effectiveness of planning and operating procedures for electric systems is evaluated while under the influence of HEMP. This assessment relies on published data and characterizes utilities using the North American Electric Reliability Council's regions and guidelines to model electric power system planning and operations. Key issues addressed by the report include how electric power systems are affected by HEMP and what actions electric utilities can initiate to reduce the consequences of HEMP. The report also reviews the salient features of earlier HEMP studies and projects, examines technology trends in the electric power industry which are affected by HEMP, characterizes the vulnerability of power systems to HEMP, and explores the capability of electric systems to recover from a HEMP event.

  3. Pembuatan Dokumen Sop Keamanan Aset Informasi Yang Mengacu Pada Kontrol Kerangka Kerja Iso 27002:2013 (Studi Kasus : Cv Cempaka Tulungagung

    Directory of Open Access Journals (Sweden)

    Dheni Indra Rachmawan

    2017-03-01

    Full Text Available Dalam mendukung proses bisnis utamanya, suatu organisasi membutuhkan adanya dukungan teknologi informasi. Penggunaan Teknologi Informasi di banyak perusahaan telah menjadi satu hal penting dalam meningkatkan efektifitas dan efisiensi operasional bisnis yang mendukung tercapainya tujuan perusahaan, termasuk juga pada CV Cempaka Tulungagung. Dalam memenuhi kebutuhan keamanan aset informasi tersebut maka diperlukan adanya sebuah tata kelola dalam bentuk dokumen SOP (Standard Operating Procedure keamanan aset informasi untuk mengurangi adanya ancaman dan risiko serta untuk mendukung penyelarasan pencapaian tujuan organisasi dalam proses bisnisnya. Metode penelitian yang digunakan yaitu OCTAVE sebagai pengolah hasil informasi yang didapatkan dari wawancara dan FMEA digunakan untuk menghitung seberapa tinggi dampak untuk perusahaan jika risiko itu terjadi dan membuat ranking prioritas untuk masing-masing risiko. Kemudian basis yang digunakan dalam membuat prosedur kendali akses aset informasi sebagai manajemen risiko adalah kerangka kerja ISO/IEC:27002:2013. Dalam penelitian ini, hasil akhir yang didapatkan adalah sebuah dokumen SOP yang sesuai dengan kebutuhan keamanan informasi bagi perusahaan CV Cempaka berdasarkan pada kontrol kerangka kerja ISO27002:2013.

  4. Poralaitteen SOP-ohjeiden kehittäminen

    OpenAIRE

    2015-01-01

    Työ tehtiin Sandvik Mining and Construction Oy:n tuotannonkehityksen tilauksesta. Työn tarkoituksena oli maanalaisen tunnelinporauslaitteen loppukokoonpanon SOP-ohjeiden kehittäminen uuteen standardiin. Osana työtä oli arvioida ja kehittää uutta standardia ja tutkia, miten se toimii käytännössä. SOP-ohjeiden tavoitteena on parantaa työn laatua, tehokkuutta ja turvallisuutta. Vakioidulla työjärjestyksellä parannetaan tuottavuutta. Uudella vakioidulla SOP-ohjeistuksella oli käyttötarve myös...

  5. A Multiscale Enrichment Procedure for Nonlinear Monotone Operators

    KAUST Repository

    Efendiev, Yalchin R.

    2014-03-11

    In this paper, multiscale finite element methods (MsFEMs) and domain decomposition techniques are developed for a class of nonlinear elliptic problems with high-contrast coefficients. In the process, existing work on linear problems [Y. Efendiev, J. Galvis, R. Lazarov, S. Margenov and J. Ren, Robust two-level domain decomposition preconditioners for high-contrast anisotropic flows in multiscale media. Submitted.; Y. Efendiev, J. Galvis and X. Wu, J. Comput. Phys. 230 (2011) 937–955; J. Galvis and Y. Efendiev, SIAM Multiscale Model. Simul. 8 (2010) 1461–1483.] is extended to treat a class of nonlinear elliptic operators. The proposed method requires the solutions of (small dimension and local) nonlinear eigenvalue problems in order to systematically enrich the coarse solution space. Convergence of the method is shown to relate to the dimension of the coarse space (due to the enrichment procedure) as well as the coarse mesh size. In addition, it is shown that the coarse mesh spaces can be effectively used in two-level domain decomposition preconditioners. A number of numerical results are presented to complement the analysis.

  6. New Procedure for Account Operations at the CERN Service Desk

    CERN Document Server

    The Computer Security Team

    2011-01-01

    Who can activate your computing account? Who can unblock it? And who can reset your password if you've forgotten it? Until recently, users who addressed such problems to the Service Desk were asked a set of questions...   The corresponding answers were designed to properly verify the requestor’s identity such that only the real owner could activate/unblock/reset his computing account. However, it turned out that the answers were easily obtainable (and that there is no better set of questions to ask). Therefore, in order to ensure optimal protection of your account, this procedure will be replaced on 28 November 2011. From that date on, users will be asked to produce a physical ID when requesting the Service Desk to perform operations like computer account activation, account unblocking or password resets. This physical ID can either be a passport/ID card or the CERN access card. If you need to activate/unblock/reset your computing account, you will either have to produ...

  7. Quality assurance: Importance of systems and standard operating procedures

    Directory of Open Access Journals (Sweden)

    Kishu Manghani

    2011-01-01

    Full Text Available It is mandatory for sponsors of clinical trials and contract research organizations alike to establish, manage and monitor their quality control and quality assurance systems and their integral standard operating procedures and other quality documents to provide high-quality products and services to fully satisfy customer needs and expectations. Quality control and quality assurance systems together constitute the key quality systems. Quality control and quality assurance are parts of quality management. Quality control is focused on fulfilling quality requirements, whereas quality assurance is focused on providing confidence that quality requirements are fulfilled. The quality systems must be commensurate with the Company business objectives and business model. Top management commitment and its active involvement are critical in order to ensure at all times the adequacy, suitability, effectiveness and efficiency of the quality systems. Effective and efficient quality systems can promote timely registration of drugs by eliminating waste and the need for rework with overall financial and social benefits to the Company.

  8. Sales and operations planning

    DEFF Research Database (Denmark)

    Kjellsdotter, Linea; Dukovska-Popovska, Iskra; Kaipia, Riikka

    2015-01-01

    This paper investigates sales and operations planning (S&OP) at four Scandinavian industrial food producers in order to explore how the use of S&OP might help leaders to deal with the challenges set by the planning environment. Variables connected to the product and market, e.g., frequency of new...

  9. Sales and operations planning

    DEFF Research Database (Denmark)

    Kjellsdotter, Linea; Dukovska-Popovska, Iskra; Kaipia, Riikka

    2013-01-01

    This paper explores how the use of sales and operations planning (S&OP) may deal with the challenges set by the planning environment by investigating S&OP at four Scandinavian industrial food producers. Variables connected to the product and market, e.g. perishability, customer service elements...

  10. Sales and operations planning

    DEFF Research Database (Denmark)

    Kjellsdotter, Linea; Dukovska-Popovska, Iskra; Kaipia, Riikka

    2013-01-01

    This paper explores how the use of sales and operations planning (S&OP) may deal with the challenges set by the planning environment by investigating S&OP at four Scandinavian industrial food producers. Variables connected to the product and market, e.g. perishability, customer service elements...

  11. Review of SOP's for Prodcutivity Surveys for EP tundra swans

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report reviews the SOPs for productivity surveys of tundra swans to identify areas of improvement. An average of 18,700 swans has been surveyed in the Atlantic...

  12. In-office vs. operating room procedures for recurrent respiratory papillomatosis.

    Science.gov (United States)

    Miller, Anya J; Gardner, Glendon M

    2017-01-01

    We conducted a study to analyze hospital and patient costs, outcomes, and patient satisfaction among adults undergoing in-office and operating room procedures for the treatment of recurrent respiratory papillomatosis. Our final study population was made up of 17 patients-1 man and 16 women, aged 30 to 86 years (mean: 62). The mean number of in-office laser procedures per patient was 4.2, and the mean interval between procedures was 5.4 months (although 10 patients underwent only 1 office procedure); the mean number of operating room procedures was 13.5, and the mean interval between procedures was 14.3 months. An equal number of patients reported complications or adverse events with the two types of procedures-5 each. The difference in cost between the office procedure (mean: $3,413.00) and the operating room procedure (mean: $12,382.59) was almost $9,000, but these savings were offset by the fact that the office procedures needed to be performed three times as often. Patients reported slightly more anxiety and discomfort during the office procedures and, overall, they appeared to prefer the operating room procedure. We conclude that office procedures are significantly more cost-effective than operating room procedures, but their use may be limited by patient tolerance and the increased frequency of the procedure.

  13. 借鉴GLP规范涂料实验室:SOP建设与实施%The Coatings Laboratory Conduction According to GLP:SOP Practice and develops

    Institute of Scientific and Technical Information of China (English)

    田乐; 李秀玲; 魏浩

    2010-01-01

    介绍了GLP(Good Laboratory practice)和SOP(Standard Operating Procedures)的发展过程与实际意义,并将SOP作为管理理念引入涂料实验室建设与管理.探讨了涂料实验室SOP建设的意义、特点、范围和内容.指出SOP建设与实施可以保障实验室安全、高效运行,保证研究工作质量和研究资料可比性、完整性与准确性.

  14. SOP 堆芯次临界状态监测问题研究%Research of Core Subcriticality Monitoring Problem in SOP

    Institute of Scientific and Technical Information of China (English)

    王振营; 孙晨; 刘建新

    2014-01-01

    the responses of IRC ( Intermediate Range Channel) to some physical phenomena in post accident,in-cluding the drop down of reactor cluster control assemblies (N-1) after reactor trip,the flooding of reactor pit, reactor core void fraction and reactor core exposed etc,are analyzed.Analysis result shows that the response of IRC does not always reflect the state of subcriticality in reactor core in accident conditions.From the purpose of core subcriticality monitoring in SOP ( State Oriented Procedure) point of view,the threshold selection of core subcriticality monitoring and priority determination of primary state function monitoring in SOP are suggested.%对事故后一些物理现象下的堆外中间量程测量通道IRC( Intermediate Range Channel)的响应进行了分析,包括停堆后( N-1)组控制棒组件下落、反应堆水池淹没、堆芯空泡份额或堆芯裸露等。分析发现,事故工况下IRC的响应并不一定反映堆芯次临界度的变化。从状态导向事故运行程序SOP ( State Oriented Procedure)堆芯次临界度监测的目的出发,对SOP中堆芯次临界度监测阈值的选取和一回路状态功能监测优先级的确定给出了建议。

  15. Quantifying the step following level of an operator in proceduralized scenarios

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Yoc Han; Jung, Wondea [KAERI, Daejeon (Korea, Republic of)

    2012-10-15

    In nuclear power plants, operators of the main control rooms cope with abnormal or emergency situations using relevant procedures. However, there exist several features that challenge step by step following of the procedures: ambiguous descriptions of procedures, dynamic situations of power plants, operational tendencies of operators, and so on. To identify and manage the features, it is useful to quantifying how compliantly an operator follows the steps of the procedures. There was little research that measures the step following level of an operator. Kim et al. presented a measure, VPP (variability of procedure progression), to estimate a variability of ways to follow a given procedure. However, VPP has some characteristics to be evaluated. First, VPP score is related with the number of step in each procedure progression. Second, VPP score is also affected by the number of progressions. In addition, VPP score implies a variability of procedure progressions, not a compliance of a progression with the given procedure. If all operators do not follow a sequence of steps in a procedure but show similar procedure progressions, the VPP score of the progressions will be low. Therefore, it is necessary to develop another measure that is capable to explain more closely the step following level. In this light, we propose a new measure, PCL (procedure compliance level) to estimate how a procedure progression is similar to the standard progressions. This paper introduces the algorithm of this measure and shows its applicability by presenting a result that is applied to a digitalized control room.

  16. THE ASSESSMENT PROCEDURE OF THE OPERATIONAL RISK EVENTS

    OpenAIRE

    2009-01-01

    A credit institution must establish a management framework of the operational risk.This framework must cover the appetite and tolerance to the operational risk of a credit institution,in accordance with the management policies of this risk, including the measure and method inwhich the operational risk is transferred outside the credit institution.The management framework of the operational risk should include policies and processes for theidentification, assessment, monitoring and control/dim...

  17. 47 CFR 80.103 - Digital selective calling (DSC) operating procedures.

    Science.gov (United States)

    2010-10-01

    ... accordance with 5 U.S.C. 552(a) and 1 CFR part 51. Copies of this standard can be inspected at the Federal... 47 Telecommunication 5 2010-10-01 2010-10-01 false Digital selective calling (DSC) operating... Procedures-General § 80.103 Digital selective calling (DSC) operating procedures. (a) Operating...

  18. 7 CFR 70.110 - Requirements for sanitation, facilities, and operating procedures in official plants.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Requirements for sanitation, facilities, and operating... Requirements for sanitation, facilities, and operating procedures in official plants. (a) The requirements for sanitation, facilities, and operating procedures in official plants shall be the applicable provisions...

  19. Developing operating procedures for a low-level radioactive waste disposal facility

    Energy Technology Data Exchange (ETDEWEB)

    Sutherland, A.A.; Miner, G.L.; Grahn, K.F.; Pollard, C.G. [Rogers and Associates Engineering Corp., Salt Lake City, UT (United States)

    1993-10-01

    This document is intended to assist persons who are developing operating and emergency procedures for a low-level radioactive waste disposal facility. It provides 25 procedures that are considered to be relatively independent of the characteristics of a disposal facility site, the facility design, and operations at the facility. These generic procedures should form a good starting point for final procedures on their subjects for the disposal facility. In addition, this document provides 55 annotated outlines of other procedures that are common to disposal facilities. The annotated outlines are meant as checklists to assist the developer of new procedures.

  20. Pseudogenization of sopA and sopE2 is functionally linked and contributes to virulence of Salmonella enterica serovar Typhi.

    Science.gov (United States)

    Valenzuela, L M; Hidalgo, A A; Rodríguez, L; Urrutia, I M; Ortega, A P; Villagra, N A; Paredes-Sabja, D; Calderón, I L; Gil, F; Saavedra, C P; Mora, G C; Fuentes, J A

    2015-07-01

    The difference in host range between Salmonella enterica serovar Typhimurium (S. Typhimurium) and S. enterica serovar Typhi (S. Typhi) can be partially attributed to pseudogenes. Pseudogenes are genomic segments homologous to functional genes that do not encode functional products due to the presence of genetic defects. S. Typhi lacks several protein effectors implicated in invasion or other important processes necessary for full virulence of S. Typhimurium. SopA and SopE2, effectors that have been lost by pseudogenization in S. Typhi, correspond to an ubiquitin ligase involved in cytokine production by infected cells, and to a guanine exchange factor necessary for invasion of epithelial cells, respectively. We hypothesized that sopA and/or sopE pseudogenization contributed to the virulence of S. Typhi. In this work, we found that S. Typhi expressing S. Typhimurium sopE2 exhibited a decreased invasion in different epithelial cell lines compared with S. Typhi WT. S. Typhimurium sopA completely abolished the hypo-invasive phenotype observed in S. Typhi expressing S. Typhimurium sopE2, suggesting that functional SopA and SopE2 participate concertedly in the invasion process. Finally, the expression of S. Typhimurium sopA and/or sopE2 in S. Typhi, determined changes in the secretion of IL-8 and IL-18 in infected epithelial cells.

  1. Posthysterectomy vault prolapse of vaginal walls: Choice of operating procedure

    Directory of Open Access Journals (Sweden)

    Argirović Rajka

    2012-01-01

    Full Text Available Post-hysterectomy vaginal vault prolapse is a common complication following different types of hysterectomy with a negative impact on the woman’s quality of life due to associated urinary, anorectal and sexual dysfunction. A clear understanding of the supporting mechanisms for the uterus and vagina is important in order to make the right choice of the corrective procedure and also to minimize the risk of posthysterectomy occurrence of vault prolapse. Preexisting pelvic floor defect prior to hysterectomy is the single most important risk factor for vault prolapse. Various surgical techniques have been advanced in hysterectomy to prevent vault prolapse. Vaginal vault repair can be carried out abdominally or vaginally. Sacrospinous fixation and abdominal sacrocolpopexy are the commonly performed procedures. The vaginal approach for vault prolapse is superior to the abdominal approach in terms of complication rates, blood loss, postoperative discomfort, length of hospital stay and costeffectiveness. Moreover, it allows the simultaneous repair of all coexistent pelvic floor defects, such as cystocele, enterocele and rectocele. Abdominal sacrocolpopexy is associated with a lower rate of recurrent vault prolapse and dyspareunia than the vaginal sacrospinous colpopexy. Other less commonly performed procedures include uterosacral ligament suspension and illeococcygeal fixation with a high risk of ureteric injury. Surgical mesh of non-absorbent material is gaining in popularity and preliminary data from vaginal mesh procedures is encouraging.

  2. General Operational Procedure for Pedestrian Radiation Portal Monitors

    Energy Technology Data Exchange (ETDEWEB)

    Belooussov, Andrei V. [Los Alamos National Laboratory

    2012-08-08

    This document outlines the basic conduct of operation (CONOPS) for a pedestrian radiation portal monitor (RPM), provided that the CONOPS is not facility or RPM specific and that it is based on a general understanding of a pedestrian RPM operation. The described CONOPS for a pedestrian RPM is defined by: (1) RPM design and operational characteristics, (2) type of pedestrian traffic, and (3) goal for RPM installation. Pedestrian RPMs normally are deployed for the continuous monitoring of individuals passing through point of control to detect the unauthorized traffic of radioactive/nuclear materials. RPMs generally are designed to detect gamma- and neutron-emitting materials.

  3. 7 CFR 205.662 - Noncompliance procedure for certified operations.

    Science.gov (United States)

    2010-01-01

    ... MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) ORGANIC FOODS PRODUCTION ACT PROVISIONS NATIONAL ORGANIC PROGRAM Administrative Compliance § 205.662... of a certified operation by a certifying agent or a State organic program's governing State...

  4. Test Operations Procedure (TOP) 4-2-013 Commodity Engineering Test Procedures, Recoilless Rifle Ammunition

    Science.gov (United States)

    2009-09-22

    External Fire, and Munition Test Procedures. The critical requirements of the STANAG are: (a) The test is done in an enclosed hearth designed...of STANAG 4240. However, the procedures of the STANAG are not amenable to satisfying the TB due to the confinement of the required hearth . c...within the hearth or bonfire. (4) Observations photographs of any reactions such as burning or explosions. TOP 4-2-013 22 September 2009

  5. Building Global Partnerships: Cooperative Maritime Security Operations as the Most Effective Fire of 21st Century Warfare

    Science.gov (United States)

    2008-10-31

    described in a speech by the Malaysian Minister of Defense Dato Abd Razak, “PACOM has mobile training teams that could assist us in acquiring a number of...Training, and Procedures (TTPs) and Standard Operating Procedures (SOPs). 20 Dato ’ Sri Mohd Najib Tun Haji Abd Razak. “Enhancing Maritime...Seapower, Washington DC, 2007. Dato ’ Sri Mohd Najib Tun Haji Abd Razak. “Enhancing Maritime Security Cooperation,” Military Technology 29, Iss. 12

  6. Preparation, control, and use of standard operating procedures in a space simulation laboratory

    Science.gov (United States)

    Parish, R. P., Jr.

    1975-01-01

    The degree of success in the operation of a space simulation laboratory is a direct function of the role of its standard operating procedures. Their proper use in a thermal vacuum test effects a wellrun test program. Preparation and procedure control are discussed.

  7. 9 CFR 354.210 - Minimum standards for sanitation, facilities, and operating procedures in official plants.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Minimum standards for sanitation, facilities, and operating procedures in official plants. 354.210 Section 354.210 Animals and Animal Products... sanitation, facilities, and operating procedures in official plants. The provisions of §§ 354.210 to...

  8. Evaluating the performance of survey-based operational management procedures

    NARCIS (Netherlands)

    Pomarede, M.; Hillary, R.; Ibaibarriaga, L.; Bogaards, J.A.; Apostolaki, P.

    2010-01-01

    The design and evaluation of survey-based management strategies is addressed in this article, using three case-study fisheries: North Sea herring, Bay of Biscay anchovy and North Sea cod, with a brief history and the main management issues with each fishery outlined. A range of operational managemen

  9. Test Operations Procedure (TOP) 06-2-301 Wind Testing

    Science.gov (United States)

    2017-06-14

    presentation of data is often dependent upon how the post-test analysis will be conducted. Data can be presented as contour maps, plots, charts ...distribution is unlimited. 13. SUPPLEMENTARY NOTES Defense Technical Information Center (DTIC), AD No.: 14. ABSTRACT This Test Operations...specific test requirements and wind testing facility capabilities. When testing large structures, such as towers, the structural analysis team should

  10. Bacterial DNA segregation by dynamic SopA polymers

    OpenAIRE

    2005-01-01

    Many bacterial plasmids and chromosomes rely on ParA ATPases for proper positioning within the cell and for efficient segregation to daughter cells. Here we demonstrate that the F-plasmid-partitioning protein SopA polymerizes into filaments in an ATP-dependent manner in vitro, and that the filaments elongate at a rate that is similar to that of plasmid separation in vivo. We show that SopA is a dynamic protein within the cell, undergoing cycles of polymerization and depolymerization, and shut...

  11. 30 CFR 250.174 - When may the Regional Supervisor grant or direct an SOP?

    Science.gov (United States)

    2010-07-01

    ... direct an SOP? 250.174 Section 250.174 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE... § 250.174 When may the Regional Supervisor grant or direct an SOP? The Regional Supervisor may grant or direct an SOP when the suspension is in the national interest, and it is necessary because the...

  12. Standard Operating Procedure for the Preparation of Lead-Containing Paint Films and Lead-in-Paint Diagnostic Test Materials

    Science.gov (United States)

    This SOP describes the preparation of stand-alone, lead paint films, prepared according to the old paint recipes. Further, this SOP describes the use of these paint films for the preparation of simulated old paints on a variety of substrates. Substrates used included wood, stee...

  13. 临床试验标准操作规程管理系统的设计与应用%Design and Application of Standard Operation Procedure Management System of Clinical Trials

    Institute of Scientific and Technical Information of China (English)

    徐帆; 徐贵丽; 杨品; 李皓瑜; 周涛; 简叡

    2011-01-01

    OBJECTIVE: To achieve electronic management of standard operation procedure, and to improve standard implementation of clinical trial. METHODS: The standard operation procedure management system of clinical trials which was based on B/S structure was independently developed and adopted. RESULTS: The modular design was adopted in the system. It included role management, document review, reading and file management, audit trail management and so on. There were clear step of SOP management process, responsibility and authority. Dilatory and evasive style of manual mode had been avoided. CONCLUSION: The application of this system improves the management and implementation of standard operation procedure. It is a new standard operation procedure management system of clinical trials%目的:实现临床试验标准操作规程管理的电子化,以促进药物临床试验各项行为规范实施.方法:自主研发基于浏览器/服务器(B/S)结构的临床试验标准操作规程管理系统并加以应用.结果:该系统采用模块化设计,具有用户权限管理,文件审核、阅读、档案管理.稽查留痕管理等功能.该系统的应用使得整个标准操作规程管理流程清楚,责权明晰,避免了手工管理模式中拖拉、推诿的现象发生.结论:该系统的应用有利于临床试验标准操作规程的管理与落实,是一种新型的临床试验质量控制管理模式.

  14. 50 CFR 260.103 - Operations and operating procedures shall be in accordance with an effective sanitation program.

    Science.gov (United States)

    2010-10-01

    ... be in accordance with an effective sanitation program. 260.103 Section 260.103 Wildlife and Fisheries... Operations and operating procedures shall be in accordance with an effective sanitation program. (a) All..., choppers, and containers which fail to meet appropriate and adequate sanitation requirements will...

  15. The Procedure Execution Manager and Its Application to Advanced Photon Source Accelerator Operation

    Science.gov (United States)

    Saunders, C. W.; Borland, M.

    1997-05-01

    The Procedure Execution Manager (PEM) combines a complete scripting environment for coding accelerator operation procedures with a manager application for executing and monitoring of the procedures. PEM is based on Tcl/Tk, a supporting graphics library, and the dp-tcl extension for distributed processing. A careful design balance has been achieved which meets the flexibility requirements of commissioning physicists and the operations-driven need for automation and a consistent user interface. The scripting environment provides support for distributed, parallel execution of procedures along with join and controlled abort operations. The manager application allows an operator to execute a procedure in automatic, semi-automatic, or manual modes. A number of successful applications of PEM to accelerator operations have been made to date. These include startup, shutdown, and other control of the positron accumulator ring (PAR), low-energy transport lines (LET), and the booster rf systems. The PAR/LET procedures make nested use of PEM's ability to run parallel procedures. There are also a number of procedures to guide and assist tune-up operations, to make accelerator physics measurements, and to diagnose equipment.

  16. 49 CFR 192.605 - Procedural manual for operations, maintenance, and emergencies.

    Science.gov (United States)

    2010-10-01

    ... maintenance activities and for emergency response. For transmission lines, the manual must also include... control room management procedures required by § 192.631. (c) Abnormal operation. For transmission lines... gas distribution operators that are operating transmission lines in connection with their...

  17. [Autologous rib cartilage harvesting: operative procedure and postoperative pain reduction].

    Science.gov (United States)

    Rasp, G; Staudenmaier, R; Ledderose, H; Kastenbauer, E

    2000-03-01

    In reconstructive surgery there is a growing demand for cartilage grafts. For small amounts of autologous tissue, cartilage from the nasal septum or ear concha is a sufficient and reliable tissue, but in cases of extensive defects or higher mechanical load autologous rib cartilage is a commonly used transplant. Nevertheless, a serious donor-site morbidity, especially postoperative pain, has to be taken into consideration. We present a modified technique for harvesting rib cartilage with a consecutive local pain therapy. In contrast to the commonly used incision through all layers of tissue the described technique follows the anatomical structures of skin tension-lines, the fascial and muscle fibers and tissue sliding-planes. Starting with a transversal skin incisions 1.5 cm above the costal arch, longitudinal splitting of the rectus abdominis fascia and muscle, the rib cartilage of the ribs 6 to 8 can be exposed. Grafts in the size of at least 3 to 8 cm can be harvested under preservation of the perichondrium. This technique causes a high degree of stability and good function of the abdominal wall. POSTOPERATIVE PAIN THERAPY: After harvesting rib cartilage most patients complain about extensive postoperative pain. For adequate treatment the local application of a long-lasting anesthetic substance close to the intercostal nerves is helpful. The introduction of a peridural catheter opens the feasibility of continuously applying a local anesthetic for 3 to 4 days directly into the donor-site. This procedure reduces the need for general anesthetics dramatically and prevents further complications. This modified technique for harvesting rib cartilage diminishes the donor-site morbidity by reducing the risk of pneumothorax, hernias and functional deficits. Moreover, the local pain therapy assures postoperative wellness and mobility.

  18. 33 CFR Appendix D to Part 157 - Example of a Procedure for Dedicated Clean Ballast Tanks Operations

    Science.gov (United States)

    2010-07-01

    ... Dedicated Clean Ballast Tanks Operations D Appendix D to Part 157 Navigation and Navigable Waters COAST... Procedure for Dedicated Clean Ballast Tanks Operations 1. Source. The example procedure for dedicated clean... Protocol. 2. Example Procedure. Dedicated clean ballast tanks operational procedure: (a) Before arrival...

  19. Ultra high temperature diffusion apparatus and operating procedures

    Energy Technology Data Exchange (ETDEWEB)

    Wyrick, S.B.

    1985-11-15

    It is the purpose of this paper to present an experimental apparatus which is capable of measuring diffusion coefficients of interdiffusing gases in the temperature range 300K to 2500K. Because of the high temperatures which will be encountered, a special alloy of tantalum (T-111) is used to house the diffusion process. This T-111 diffusion cell is heated via radiation heat from a tungsten heating element powered by a Saban saturable reactor power supply. The diffusion cell heating element are encased in a nickel-plated copper cooling can. This entire assembly is enclosed in an Ultek vacuum chamber to prevent oxidation of the diffusion cell. This report covers the construction and calibration of the diffusion cell, details of the gas loading and sampling system, and complete information on the components required to operate the vacuum furnace. Thus far, several experiments have been run in the temperature range 600K to 800K and the resulting diffusion coefficients agree fairly well with previously published values. 21 refs., 9 figs., 4 tabs.

  20. STUDY ON PROCEDURES FOR OPERATIONAL OBJECTIVES IN PHYSICAL EDUCATION

    Directory of Open Access Journals (Sweden)

    Cojanu Florin

    2009-03-01

    Full Text Available INTRODUCTIONIn general, educational goals and / or instructional purposes are pursued by the processes of education orteaching activities, such as learning skills and ability to drive the development of cognitive skills (understanding,application, analysis, synthesis emotional (reactions, feelings , will, perseverance, inclinations psihomotric(collection, disposal, automatism, etc. driven side. growing health training driving skills, etc. ..They are a target or purpose teaching subjects to be conducted systematically and rigorously the process ofconducting training or other education-training activities of the human personality.Specifying the correct targets is a fundamental requirement of designing teaching activities. Specifying theobjectives of education, training, information, etc., is achieved through logical operations or judgments,subsidized by the correct and precise answers to four fundamental questions, as follows:1. "What we want to do? 2.2. "What we know and will know what to do?" (Student at the end of one or more units of learning(training assembled systemic3. 3. "What use what you learn, educate, dial"4. 4. "What length of time is required?"Any type of project is being developed "from the end", with the thought and image of the final product youwant to realize it. This purpose may be placed at the end of a cycle of learning (school, school, university.These types of targets determine the contents of various analytical programs of instruction (for the recoveryof knowledge, ownership of new acquisitions and continuous improvement. Largely from physical educationlessons are devoid of quality and efficiency expected, due to errors that are committed in the methodology ofdetermining educational objectives-training or instruction.

  1. User centered design of a digital procedure guidance component for nuclear power plant operation

    Energy Technology Data Exchange (ETDEWEB)

    Carvalho, Paulo V.R. de; Santos, Isaac L. dos; Oliveira, Mauro V. de; Grecco, Claudio H.S.; Mol, Antonio C. [Instituto de Engenharia Nuclear (IEN/CNEN-RJ), Rio de Janeiro, RJ (Brazil)]. E-mails: paulov@ien.gov.br; luquetti@ien.gov.br; mvitor@ien.gov.br; grecco@ien.gov.br; mol@ien.gov.br

    2007-07-01

    The use of nuclear power plants to produce electric energy is a safety-critical process where ultimate operational decisions still relies with the control room operators. Thus it is important to provide the best possible decision support through effective supervisory control interfaces. A user centered design approach, based on cognitive task analysis methods, was used to observe the operators training on the nuclear power plant simulator of the Human System Interface Laboratory (LABIHS). We noted deficiencies in the integration between the computerized interfaces and the hardcopy (paper) procedures. An new prototype of digital procedures - the digital procedure component guidance (PCG) - was designed in PowerPoint as an alternative to the current hardcopy procedure manuals. The design improves upon the graphical layout of system information and provides better integration of procedures, automation, and alarm systems. The design was validated by expert opinion and a scenario-based comparison. Future implementation and testing of the redesign is suggested for further validation. (author)

  2. Soil washing physical separations test procedure - 300-FF-1 operable unit

    Energy Technology Data Exchange (ETDEWEB)

    Belden, R.D.

    1993-10-08

    This procedure provides the operations approach, a field sampling plan, and laboratory procedures for a soil washing test to be conducted by Alternative Remedial Technologies, Inc. (ART) in the 300-FF-1 area at the Hanford site. The {open_quotes}Quality Assurance Project Plan for the Soil Washing Physical Separations Test, 300-FF-1 Operable Unit,{close_quotes} Hanford, Washington, Alternative Remedial Technologies, Inc., February 1994 (QAPP) is provided in a separate document that presents the procedural and organizational guidelines for this test. This document describes specifications, responsibilities, and general procedures to be followed to conduct physical separation soil treatability tests in the North Process Pond of the 300-FF-1 Operable Unit (OU) at the Hanford Site. These procedures are based on the {open_quotes}300-FF-1 Physical Separations CERCLA Treatability Test Plan, DOE/RL 92-2l,{close_quotes} (DOE-RL 1993).

  3. Hand washing in operating room: a procedural comparison

    Directory of Open Access Journals (Sweden)

    Alessia Stilo

    2016-09-01

    Full Text Available BACKGROUND Hand washing has been considered a measure of personal hygiene for centuries and it is known that an improper hand hygiene by healthcare workers is responsible for about 40% of nosocomial infections. Therefore, surgical hand preparation is a critical element for healthcare safety in order to reduce microbial contamination of  surgical wound in case of non detected break of the gloves. The aim of our study is to evaluate the efficacy three antiseptics: Povi-iodine scrub; EPG (Ethanol, Hydrogen Peroxide, Glycerol, recommended by WHO, and common marseille soap type in a liquid formulation. METHODS It was designed a randomized, double-blind, single-center study conducted in the University Hospital of Messina, from January to June 2013. We asked operators to put the fingertips of their right hand (if not left-handed for one minute on the PCA medium, before washing with the three types of antiseptics, and after washing and drying. Drying was made using sterile gauzes or disposable wipes. Then, we measured the number of colony forming units per mL (CFU/mL and calculated the percentage of microbial load reduction. RESULTS 211 samples have been considered for statistical analysis: in 42 samples, in fact, initial microbial load was lower than after washing. Washing with EPG reduced CFU/ml from  a mean of 38,9 to 4,1 (86,5% reduction, washing with povi-iodine scrub from 59,55 to 12,9 (75,9% reduction and washing with Marseille soap from 47,26 to 12,7 (64,3% reduction. CONCLUSIONS Our study shows that washing with EPG has superior efficacy in CFU reduction. Antiseptic hand washing, however, cannot be considered the only measure to reduce infections: the anomaly of some results (initial microbial load lower than after washing  demonstrates that drying is an essential phase in the presurgical preparation. Therefore, hand hygiene must be part of a more complex strategy of surveillance and control of nosocomial infections

  4. Systematic Procedure for Integrated Process Operation: Reverse Electro-Enhanced Dialysis (REED) during Lactic Acid Fermentation

    DEFF Research Database (Denmark)

    Prado Rubio, Oscar Andres; Jørgensen, Sten Bay; Jonsson, Gunnar Eigil

    2011-01-01

    The integration of lactic acid fermentation and Reverse Electro-Enhanced Dialysis (REED) is investigated based upon previously developed mathematical models. A goal driven process and operation design procedure is proposed and partially investigated. The conceptual analysis of the processes...

  5. Evaluation of the Combat Vehicle Command and Control System. Operational Effectiveness of an Armor Battalion

    Science.gov (United States)

    1994-01-31

    MAJ James Whitehead, the Field Unit’s Research and Development Coordinator. Mr. Ronald Kraemer, of the ARI-Fort Knox Field Unit, and Ms. Margaret ...staff included Dr. Nancy Atwood , Dr. Beverly Winsch, Dr. Laura Ford, Ms. Alicia Sawyer, Mr. Paul Smith, Ms. Frances Ainslie, MG (Ret.) Charles Heiden, Mr...combat performance in the context of armor doctrine and tactics, including unit standing operating procedures (SOPs). A third report ( Atwood , Winsch

  6. Guidelines for the preparation of emergency operating procedures. Resolution of comments on NUREG-0799

    Energy Technology Data Exchange (ETDEWEB)

    1982-08-01

    The purpose of this document is to identify the elements necessary for utilities to prepare and implement a program of Emergency Operating Procedures (EOPs) for use by control room personnel to assist in mitigating the consequences of a broad range of accidents and multiple equipment failures. This document applies only to the EOPs so designated; it does not address emergency preparedness or emergency planning. It also represents the resolution of comments on NUREG-0799, Draft Criteria for Preparation of Emergency Operating Procedures.

  7. Reactor operating procedures for startup of continuously-operated chemical plants

    NARCIS (Netherlands)

    Verwijs, J.W.; Kösters, P.H.; Berg, van den H.; Westerterp, K.R.

    1995-01-01

    Rules are presented for the startup of an adiabatic tubular reactor, based on a qualitative analysis of the dynamic behavior of continuously-operated vapor- and liquid-phase processes. The relationships between the process dynamics, operating criteria, and operating constraints are investigated, sin

  8. Safety Precautions and Operating Procedures in an (A)BSL-4 Laboratory: 4. Medical Imaging Procedures.

    Science.gov (United States)

    Byrum, Russell; Keith, Lauren; Bartos, Christopher; St Claire, Marisa; Lackemeyer, Matthew G; Holbrook, Michael R; Janosko, Krisztina; Barr, Jason; Pusl, Daniela; Bollinger, Laura; Wada, Jiro; Coe, Linda; Hensley, Lisa E; Jahrling, Peter B; Kuhn, Jens H; Lentz, Margaret R

    2016-10-03

    Medical imaging using animal models for human diseases has been utilized for decades; however, until recently, medical imaging of diseases induced by high-consequence pathogens has not been possible. In 2014, the National Institutes of Health, National Institute of Allergy and Infectious Diseases, Integrated Research Facility at Fort Detrick opened an Animal Biosafety Level 4 (ABSL-4) facility to assess the clinical course and pathology of infectious diseases in experimentally infected animals. Multiple imaging modalities including computed tomography (CT), magnetic resonance imaging, positron emission tomography, and single photon emission computed tomography are available to researchers for these evaluations. The focus of this article is to describe the workflow for safely obtaining a CT image of a live guinea pig in an ABSL-4 facility. These procedures include animal handling, anesthesia, and preparing and monitoring the animal until recovery from sedation. We will also discuss preparing the imaging equipment, performing quality checks, communication methods from "hot side" (containing pathogens) to "cold side," and moving the animal from the holding room to the imaging suite.

  9. Ubiquitination of the bacterial inositol phosphatase, SopB, regulates its biological activity at the plasma membrane.

    LENUS (Irish Health Repository)

    Knodler, Leigh A

    2009-11-01

    The Salmonella type III effector, SopB, is an inositol polyphosphate phosphatase that modulates host cell phospholipids at the plasma membrane and the nascent Salmonella-containing vacuole (SCV). Translocated SopB persists for many hours after infection and is ubiquitinated but the significance of this covalent modification has not been investigated. Here we identify by mass spectrometry six lysine residues of SopB that are mono-ubiquitinated. Substitution of these six lysine residues with arginine, SopB-K(6)R, almost completely eliminated SopB ubiquitination. We found that ubiquitination does not affect SopB stability or membrane association, or SopB-dependent events in SCV biogenesis. However, two spatially and temporally distinct events are dependent on ubiquitination, downregulation of SopB activity at the plasma membrane and prolonged retention of SopB on the SCV. Activation of the mammalian pro-survival kinase Akt\\/PKB, a downstream target of SopB, was intensified and prolonged after infection with the SopB-K(6)R mutant. At later times, fewer SCV were decorated with SopB-K(6)R compared with SopB. Instead SopB-K(6)R was present as discrete vesicles spread diffusely throughout the cell. Altogether, our data show that ubiquitination of SopB is not related to its intracellular stability but rather regulates its enzymatic activity at the plasma membrane and intracellular localization.

  10. Field Operations and Enforcement Manual for Air Pollution Control. Volume III: Inspection Procedures for Specific Industries.

    Science.gov (United States)

    Weisburd, Melvin I.

    The Field Operations and Enforcement Manual for Air Pollution Control, Volume III, explains in detail the following: inspection procedures for specific sources, kraft pulp mills, animal rendering, steel mill furnaces, coking operations, petroleum refineries, chemical plants, non-ferrous smelting and refining, foundries, cement plants, aluminum…

  11. Operational Procedures for Successful Vocational-Technical Resource Consortia in Serving Business and Industry in Ohio.

    Science.gov (United States)

    Frasier, James E.; Stanton, William

    The development, organization, and operation of the Vocational-Technical Resource Consortia in Ohio was examined to identify those elements, policies, practices, and procedures that contribute to their effective operation and future growth. Data about individual consortia and general information were gathered by questionnaires completed by…

  12. Field Operations and Enforcement Manual for Air Pollution Control. Volume III: Inspection Procedures for Specific Industries.

    Science.gov (United States)

    Weisburd, Melvin I.

    The Field Operations and Enforcement Manual for Air Pollution Control, Volume III, explains in detail the following: inspection procedures for specific sources, kraft pulp mills, animal rendering, steel mill furnaces, coking operations, petroleum refineries, chemical plants, non-ferrous smelting and refining, foundries, cement plants, aluminum…

  13. Hanford tank waste operation simulator operational waste volume projection verification and validation procedure

    Energy Technology Data Exchange (ETDEWEB)

    HARMSEN, R.W.

    1999-10-28

    The Hanford Tank Waste Operation Simulator is tested to determine if it can replace the FORTRAN-based Operational Waste Volume Projection computer simulation that has traditionally served to project double-shell tank utilization. Three Test Cases are used to compare the results of the two simulators; one incorporates the cleanup schedule of the Tri Party Agreement.

  14. Automated Kick Control Procedure for an Influx in Managed Pressure Drilling Operations

    Directory of Open Access Journals (Sweden)

    Jing Zhou

    2016-01-01

    Full Text Available Within drilling of oil and gas wells, the Managed Pressure Drilling (MPD method with active control of wellbore pressure during drilling has partly evolved from conventional well control procedures. However, for MPD operations the instrumentation is typically more extensive compared to conventional drilling. Despite this, any influx of formation fluids (commonly known as a kick during MPD operations is typically handled by conventional well control methods, at least if the kick is estimated to be larger than a threshold value. Conventional well control procedures rely on manual control of the blow out preventer, pumps, and choke valves and do not capitalize on the benefits from the instrumentation level associated with MPD. This paper investigates two alternative well control procedures specially adapted to backpressure MPD: the dynamic shut-in (DSI procedure and the automatic kick control (AKC procedure. Both methods capitalize on improvements in Pressure While Drilling (PWD technology. A commercially available PWD tool buffers high-resolution pressure measurements, which can be used in an automated well control procedure. By using backpressure MPD, the choke valve opening is tuned automatically using a feedback-feedforward control method. The two procedures are evaluated using a high fidelity well flow model and cases from a North Sea drilling operation are simulated. The results show that using AKC procedure reduces the time needed to establish control of the well compared to DSI procedure. It also indicates that the AKC procedure reduces the total kick size compared to the DSI procedure, and thereby reduces the risk of lost circulation.

  15. Automated operator procedure prompting for startup of Experimental Breeder Reactor-2

    Energy Technology Data Exchange (ETDEWEB)

    Renshaw, A.W.; Ball, S.J.; Ford, C.E.

    1990-11-01

    This report describes the development of an operator procedure prompting aid for startup of a nuclear reactor. This operator aid is a preliminary design for a similar aid that eventually will be used with the Advanced Liquid Metal Reactor (ALMR) presently in the design stage. Two approaches were used to develop this operator procedure prompting aid. One method uses an expert system software shell, and the other method uses database software. The preliminary requirements strongly pointed toward features traditionally associated with both database and expert systems software. Database software usually provides data manipulation flexibility and user interface tools, and expert systems tools offer sophisticated data representation and reasoning capabilities. Both methods, including software and associated hardware, are described in this report. Proposals for future enhancements to improve the expert system approach to procedure prompting and for developing other operator aids are also offered. 25 refs., 14 figs.

  16. A method for risk informing procedures at operating nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, P. F.; Martin del Campo, C., E-mail: pnelson_007@yahoo.com [UNAM, Facultad de Ingenieria, Departamento de Sistemas Energeticos, Paseo Cuauhnahuac No. 8532, Col. Progreso, 62550 Jiutepec, Morelos (Mexico)

    2012-10-15

    The technical approach presented establishes a framework intended to provide the necessary elements for a deployable human performance monitoring program that incorporates insights from plant specific probabilistic risk assessments, human reliability analysis, as well as the development of plant specific human failure data. A human performance monitoring program of this structure would be used to provide the ability to risk inform procedures (e.g., operations or maintenance) to determine the operational risk significance of procedural performance (i.e., precautions, prerequisites, procedure steps), the likelihood of consequential human error dur the performance of the procedure, and the identification of procedure specific barriers to reduce or eliminate consequential human errors. The program would provide the means to assess procedures prior to execution and the means to record and trend human failure events leading to a plant specific human failure database for human activities characterized as pre-initiator. The technical methods and data processing for each of these areas are developed and presented, as well as an example application of an operational procedure error leading to a plant level event (i.e, plant trip). (Author)

  17. Stimulus representation in SOP: I. Theoretical rationalization and some implications.

    Science.gov (United States)

    Brandon, Susan E.; Vogel, Edgar H.; Wagner, Allan R.

    2003-04-28

    THE SOP MODEL [INFORMATION PROCESSING IN ANIMALS: Memory Mechanisms, Erlbaum, Hillsdale, NJ, 1981, p. 5] is described in terms of its assumed stimulus representation, network characteristics, and rules for learning and performance. It is shown how several Pavlovian conditioning phenomena can be accounted on the basis of the model's presumed stimulus representation. Challenges to the SOP model prompted the adoption of a componential stimulus representation in: AESOP [Contemporary Learning Theories: Pavlovian Conditioning and the Status of Traditional Learning Theory, Erlbaum, Hillsdale, NJ, 1989, p. 149], this was a dual representation of the unconditioned stimulus (US), and C-SOP [Contemporary Learning: Theory and Application, Erlbaum, Mahwah, NJ, 2001, p. 23], this was a multi-component representation of the conditioned stimulus (CS). The assumption of a componential CS representation, where large numbers of elements can be separately learned about, necessitated a modification of the learning rule. The modified, "constrained" rule was found useful to explain timing characteristics of Pavlovian conditioned responses, as well as data offered by Rescorla [J. Exp. Psychol. Anim. Behav. Process. 26 (2000) 428; Q. J. Exp. Psychol. 54B (2001) 53; J. Exp. Psychol. Anim. Behav. Process. 28 (2002) 163] showing that stimuli trained in compound do not share the same quantitative fate.

  18. Safety rules during operation in sewage networks; Procedure di sicurezza sul lavoro per interventi in fognatura

    Energy Technology Data Exchange (ETDEWEB)

    Bonvicini, V.; Cervi, G.; Lastrico, G.; Siri, R. [Azienda Municipalizzata Gas e Acqua, A.M.G.A., Genoa (Italy)

    1998-04-01

    The paper describes the risks evaluation and the safety rules for operations of detecting of sewage networks. There are also described the possibility of gas formation in the network and the safety rules in this particularly work conditions. [Italiano] L`articolo espone la valutazione dei rischi e le relative procedure di sicurezza durante le operazioni di ispezione dei condotti fognari. Siconsidera inoltre la possibilita` di formazione di gas pericolosi e le procedure di sicurezza da adottare in questi casi.

  19. Risk of Venous Thromboembolism and Operative Duration in Patients Undergoing Neurosurgical Procedures.

    Science.gov (United States)

    Bekelis, Kimon; Labropoulos, Nicos; Coy, Shannon

    2017-05-01

    The association of operative duration with the risk of venous thromboembolism (VTE) has not been quantified in neurosurgery. To investigate the association of surgical duration for several neurosurgical procedures and the incidence of VTE. We performed a retrospective cohort study involving patients who underwent neurosurgical procedures from 2005 to 2012 and were registered in the American College of Surgeons National Quality Improvement Project registry. In order to control for confounding, we used multivariable regression models, and propensity score conditioning. During the study period, there were 94 747 patients, who underwent neurosurgical procedures, and met the inclusion criteria. Of these, 1358 (1.0%) developed VTE within 30 days postoperatively. Multivariable logistic regression demonstrated an association of longer operative duration with higher 30-day incidence of VTE (odds ratio [OR], 1.22; 95% confidence interval [CI], 1.19-1.25). Compared with procedures of moderate duration (third quintile, 40-60th percentile), patients undergoing the longest procedures (>80th percentile) had higher odds (OR, 3.15; 95% CI, 2.49-3.99) of developing VTE. The shortest procedures (<20th percentile) were associated with a decreased incidence of VTE (OR, 0.51; 95% CI, 0.27-0.76) in comparison to those of moderate duration. The same associations were present in propensity score-adjusted models, and models stratified by subgroups of cranial, spinal, peripheral nerve, and carotid procedures. In a cohort of patients from a national prospective surgical registry, increased operative duration was associated with increased incidence of VTE for neurosurgical procedures. These results can be used by neurosurgeons to inform operative management, and to stratify patients with regard to VTE risk.

  20. Antimicrobial Testing Methods & Procedures: MB-17-03

    Science.gov (United States)

    Information about ATMP - SOP Neutralization Confirmation Procedures for the AOAC Use-dilution method (UDM), the AOAC Germicidal Spray Products as Disinfectants Test (GSPT) and the Disinfectant Towelette Test (DTT) - MB-17-03

  1. Towards Verification of Operational Procedures Using Auto-Generated Diagnostic Trees

    Science.gov (United States)

    Kurtoglu, Tolga; Lutz, Robyn; Patterson-Hine, Ann

    2009-01-01

    The design, development, and operation of complex space, lunar and planetary exploration systems require the development of general procedures that describe a detailed set of instructions capturing how mission tasks are performed. For both crewed and uncrewed NASA systems, mission safety and the accomplishment of the scientific mission objectives are highly dependent on the correctness of procedures. In this paper, we describe how to use the auto-generated diagnostic trees from existing diagnostic models to improve the verification of standard operating procedures. Specifically, we introduce a systematic method, namely the Diagnostic Tree for Verification (DTV), developed with the goal of leveraging the information contained within auto-generated diagnostic trees in order to check the correctness of procedures, to streamline the procedures in terms of reducing the number of steps or use of resources in them, and to propose alternative procedural steps adaptive to changing operational conditions. The application of the DTV method to a spacecraft electrical power system shows the feasibility of the approach and its range of capabilities

  2. Design and evaluation of computerized operating procedures in nuclear power plants.

    Science.gov (United States)

    Hwang, Fei-Hui; Hwang, Sheue-Ling

    2003-01-15

    A small-scale virtual system has been developed in this study to enhance operators' understanding and operating performance. For this, a computerized graphical interface based on Dynamic Work Causality Equation (DWCE) has been designed to transform the operating procedure into a flowchart. Furthermore, the Programmable Logic Controller (PLC) was installed to connect the signboard (proposed system) with the computerized graphical interface. An experiment was conducted to verify the effect of computerized graphic interface, indicating that the computerized system significantly decreases learning time and improves operational performance.

  3. Improving the review of standard operating procedures: a novel electronic system for compounding pharmacies.

    Science.gov (United States)

    Brensel, Robert; Brensel, Scott; Ng, Amy

    2013-01-01

    Since the New England Compounding Center disaster in 2012, the importance of following correct procedures during every phase of customized pharmacy has been a focus of governmental interest and action as well as public scrutiny. Many pharmacies rely on the rote review of standard operating procedures to ensure that staff members understand and follow protocols that ensure the safety and potency of all compounds prepared, but that approach to continuing education can be cumbersome and needlessly time-consuming. In addition, documenting and retrieving evidence of employee competence can be difficult. In this article, we describe our use of online technology to improve our methods of educating staff about the full range of standard operating procedures that must be followed in our pharmacy. The system we devised and implemented has proven to be effective, easy to update and maintain, very inexpensive, and user friendly. Its use has reduced the time previously required for a read-over review of standard operating procedures from 30 or 40 minutes to 5 or 10 minutes in weekly staff meetings, and we can now easily document and access proof of employees' comprehension of that content. It is our hope that other small compounding pharmacies will also find this system of online standard operating procedure review helpful.

  4. Operational circular No. 9 – Principles and procedures governing complaints of harassment

    CERN Multimedia

    HR Department

    2011-01-01

    Operational Circular No. 9 entitled "Principles and Procedures Governing Complaints of Harassment", approved by the Director-General following discussion in the Standing Concertation Committee meeting on 21 March 2011, is available on the intranet site of the Human Resources Department: https://cern.ch/hr-docs/opcirc/opcirc.asp Operational Circular No. 9 is applicable to any person working at or on behalf of CERN. It cancels and replaces Administrative Circular No. 32 entitled "Principles and Procedures Governing Complaints of Harassment” of February 2000. Department Head Office

  5. A hypertext information system for standard operating procedures in haematological intensive care.

    Science.gov (United States)

    Horsch, A; Sokol, R; Heneka, D; Lasic, G

    1997-01-01

    In times of cost reduction efforts the role of standard operating procedures for both medical and nursing procedures gets increasing importance. Such standards are necessary if the quality of patient care shall not suffer but even improve. While some sophisticated approaches are coming up with generation of clinical processes from formal protocol models in connection with documentation systems the clinical practice actually looks quite different: Paper-based "operating standards" are used in day-to-day work, if any. In this paper a simple and powerful WWW-based hypertext information system for easy provision and maintenance of nursing standards is presented.

  6. Operative vaginal delivery and invasive procedures in pregnancy among women living with HIV.

    Science.gov (United States)

    Peters, Helen; Francis, Kate; Harding, Kate; Tookey, Pat A; Thorne, Claire

    2017-03-01

    To describe the use and outcomes of operative delivery and invasive procedures in pregnancy amongst women living with HIV. The National Study of HIV in Pregnancy and Childhood (NSHPC) is a comprehensive population-based surveillance study in the UK and Ireland. The NSHPC has collected data on operative delivery since 2008, and invasive procedures in pregnancy (amniocentesis, cordocentesis, chorionic villus sampling) from 2012. Descriptive analyses were conducted on 278 pregnancies expected to deliver from 1 January 2008 with outcome reported to the NSHPC by 31 March 2016. Among 9372 pregnancies in 2008-2016, there were 9072 livebirths with 251 operative deliveries and 27 invasive procedures in pregnancy reported. Information was available for 3023/3490 vaginal deliveries, and use of forceps or vacuum reported in 251deliveries (8.2%), increasing over calendar time to almost 10% by 2014-16. Forceps were used twice as often as vacuum delivery, and forceps use increased over time. One infant delivered operatively is known to have acquired HIV. From 2012 there were 4063 pregnancies resulting in 3952 livebirths, 83 terminations and 28 stillbirths. 2163/4063 had information on use (or not) of invasive procedures in pregnancy. Amniocentesis was reported in 25/2163 pregnancies, there was one report of chorionic villus sampling and one of cordocentesis. There were no reported transmissions following invasive procedures in pregnancy. This is the largest study to date to report on operative delivery in women living with HIV on combined antiretroviral therapy (cART), and provides an up-to-date picture of invasive procedures during pregnancy in this group. Findings from this comprehensive national study are reassuring but numbers are currently low; on-going monitoring is crucial as obstetric care of women with HIV becomes normalised. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. Development of an expert system for abnormal operating procedures in a main control room.

    Science.gov (United States)

    Hsieh, Min-Han; Hwang, Sheue-Ling; Liu, Kang-Hong; Liang, Sheau-Farn Max; Chuang, Chang-Fu

    2012-01-01

    The study was conducted from the perspective of human factors engineering in order to compare the process that operators originally used to diagnose potential and actual faults with a process that included an expert system for diagnosing faults. The results of the study indicated that the existence of an expert system for fault diagnosis makes the task of fault diagnosis easier and reduces errors by quickly suggesting likely Abnormal Operating Procedures (AOPs).

  8. A QUALITATIVE EVALUATION ON SOP HRD 2007-2013 IN ROMANIA - FOCUS-GROUP STUDY

    Directory of Open Access Journals (Sweden)

    Bud Angelica Mariana

    2015-07-01

    Full Text Available This paper seeks to underline the main problems faced in implementing and using European Union (EU funds in Romania within the Sectoral Operational Programme Human Resources Development (SOP HRD during the first programing period 2007-2013. The problems and barriers revealed were identified during a focus-group for the second interim evaluation of SOPHRD, organized by the Management Authority of this program in Nord-Vest region, in November 2014. The focus-group represents a small part of the entire process of evaluating the programme for the development of human resources during its implementation, with the purpose of finding beneficiaries opinions about the efficiency, effectiveness and relevance of interventions financed through SOP HRD. Beliefs, personal recommendations from the participants are presented in order to improve the use of European funds for development of human resources (in particular and the use of structural instruments (in general. These results and solutions can be efficiently used during the next financial period 2014-2020 to create the framework for every priority axis and key areas of intervention, during the implementation of new projects and within the entire process that these funds require in order to successfully use the structural instruments to catch up with developed countries. Moreover, some of the problems identified can be found in other operational programmes and therefore, this research can be useful for every one that wants to use this kind of financing or has a project of this kind in implementation, without taking into account the European funding source. Besides the qualitative approach given by focus-group research method, this paper is going to present a general approach over SOP HRD in Romania during 2007-2013, from a quantitative perspective (number of projects submitted, approved, contracted, payment rate, absorption rate. Moreover solutions linked to knowledge management practices will be proposed

  9. 34 CFR 602.23 - Operating procedures all agencies must have.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false Operating procedures all agencies must have. 602.23 Section 602.23 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF... agencies must have. (a) The agency must maintain and make available to the public written...

  10. Characterization of Nanomaterials Using Field Flow Fractionation and Single Particle Inductively Coupled Plasma Mass Spectrometery (FFF-ICP-MS and SP-ICP-MS): Scientific Operating Procedure SOP-C

    Science.gov (United States)

    2015-04-01

    methodologies in environmental risk assessment of engineered nanoparticles. Ecotoxicology 17(5): 344-361. Heath, J. R. Size-dependent surface-plasmon...importance for determining toxicity to aquatic test organisms. Environmental Science & Technology 44(24): 9571-9577. ERDC/EL SR-15-3 25 Laborda...Wiley & Sons, Ltd. Lead, J. R., K. J. Wilkinson. 2006. Aquatic colloids and nanoparticles: current knowledge and future trends. Environmental

  11. Origin and Preparation of Standard Operation Procedure and Its Function%标准操作规程(SOP)由来、书写要求及其作用

    Institute of Scientific and Technical Information of China (English)

    张潇; 赵明海; 刘福生; 谭德讲; 李冠民

    2007-01-01

    本文对SOP的由来、目的作用、书写要求和重要性等方面进行了介绍,提供了SOP的一般书写格式,探讨了制定SOP应注意的一些问题,并就加强SOP在实验动物的饲养管理方面的重要性进行了讨论。

  12. Stepwise optimization of the procedure for assessment of circulating progenitor cells in patients with myocardial infarction.

    Directory of Open Access Journals (Sweden)

    Yu-Xin Cui

    Full Text Available BACKGROUND: The number and functional activity of circulating progenitor cells (CPCs is altered in diabetic patients. Furthermore, reduced CPC count has been shown to independently predict cardiovascular events. Validation of CPCs as a biomarker for cardiovascular risk stratification requires rigorous methodology. Before a standard operation protocol (SOP can be designed for such a trial, a variety of technical issues have to be addressed fundamentally, which include the appropriate type of red blood cell lysis buffer, FMO or isotype controls to identify rare cell populations from background noise, optimal antibody dilutions and conditions of sample storage. We herein propose improvements in critical steps of CPC isolation, antigenic characterization and determination of functional competence for final application in a prospective investigation of CPCs as a biomarker of outcome following acute myocardial infarction. METHODS AND FINDINGS: In this validation study, we refined the standard operating procedure (SOP for flow cytometry characterisation and functional analysis of CPCs from the first 18 patients of the Progenitor Cell Response after Myocardial Infarction Study (ProMIS. ProMIS aims to verify the prognostic value of CPCs in patients with either ST elevation or non-ST elevation myocardial infarction with or without diabetes mellitus, using cardiac magnetic resonance imaging (MRI for assessment of ventricular function as a primary endpoint. Results indicate crucial steps for SOP implementation, namely timely cell isolation after sampling, use of appropriate lysis buffer to separate blood cell types and minimize the acquisition events during flow cytometry, adoption of proper fluorophore combination and antibody titration for multiple antigenic detection and introduction of counting beads for precise quantification of functional CPC activity in migration assay. CONCLUSION AND SIGNIFICANCE: With systematic specification of factors influencing

  13. Construction of Project for laboratory SOP of Traditional Chinese medicine and Materia Medica%中医药实验室规范化操作规程(SOP)工程建设

    Institute of Scientific and Technical Information of China (English)

    中医现代化科技发展战略研究课题组

    2002-01-01

    本文提出了中医药实验室规范化操作(SOP)工程建设的重要意义、目标和发展思路,其主要任务为:1.实验全过程的SOP管理;2.技术资料的SOP;3.实验技术的SOP;4.仪器设备操作的SOP.

  14. A study on development of the step complexity measure for emergency operating procedures using entropy concepts

    Energy Technology Data Exchange (ETDEWEB)

    Park, J. K.; Jung, W. D.; Kim, J. W.; Ha, J. J

    2001-04-01

    In complex systems, such as nuclear power plants (NPPs) or airplane control systems, human errors play a major role in many accidents. For example, it was reported that about 70% of aviation accidents are due to human errors, and that approximately 28% of accidents in process industries are caused by human errors. According to related studies, written manuals or operating procedures are revealed as one of the most important factors in aviation and manufacturing industries. In case of NPPs, the importance of procedures is more salient than other industries because not only over 50% of human errors were due to procedures but also about 18% of accidents were caused by the failure of following procedures. Thus, the provision of emergency operating procedures (EOPs) that are designed so that the possibility of human errors can be reduced is very important. To accomplish this goal, a quantitative and objective measure that can evaluate EOPs is indispensable. The purpose of this study is the development of a method that can quantify the complexity of a step included in EOPs. In this regard, the step complexity measure (SC) is developed based on three sub-measures such as the SIC (step information complexity), the SLC (step logic complexity) and the SSC (step size complexity). To verify the SC measure, not only quantitative validations (such as comparing SC scores with subjective evaluation results and with averaged step performance time) but also qualitative validations to clarify physical meanings of the SC measure are performed.

  15. 30 CFR 250.173 - When may the Regional Supervisor direct an SOO or SOP?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false When may the Regional Supervisor direct an SOO or SOP? 250.173 Section 250.173 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE... § 250.173 When may the Regional Supervisor direct an SOO or SOP? The Regional Supervisor may direct...

  16. Safety testing and operational procedures for self-developed radiofrequency coils.

    Science.gov (United States)

    Hoffmann, Jens; Henning, Anke; Giapitzakis, Ioannis A; Scheffler, Klaus; Shajan, G; Pohmann, Rolf; Avdievich, Nikolai I

    2016-09-01

    The development of novel radiofrequency (RF) coils for human ultrahigh-field (≥7 T), non-proton and body applications is an active field of research in many MR groups. Any RF coil must meet the strict requirements for safe application on humans with respect to mechanical and electrical safety, as well as the specific absorption rate (SAR) limits. For this purpose, regulations such as the International Electrotechnical Commission (IEC) standard for medical electrical equipment, vendor-suggested test specifications for third party coils and custom-developed test procedures exist. However, for higher frequencies and shorter wavelengths in ultrahigh-field MR, the RF fields may become extremely inhomogeneous in biological tissue and the risk of localized areas with elevated power deposition increases, which is usually not considered by existing safety testing and operational procedures. In addition, important aspects, such as risk analysis and comprehensive electrical performance and safety tests, are often neglected. In this article, we describe the guidelines used in our institution for electrical and mechanical safety tests, SAR simulation and verification, risk analysis and operational procedures, including coil documentation, user training and regular quality assurance testing, which help to recognize and eliminate safety issues during coil design and operation. Although the procedure is generally applicable to all field strengths, specific requirements with regard to SAR-related safety and electrical performance at ultrahigh-field are considered. The protocol describes an internal procedure and does not reflect consensus among a large number of research groups, but rather aims to stimulate further discussion related to minimum coil safety standards. Furthermore, it may help other research groups to establish their own procedures. Copyright © 2015 John Wiley & Sons, Ltd.

  17. Konno procedure using atrioventricular groove patch plasty after arterial switch operation.

    Science.gov (United States)

    Kosaka, Yoshimichi; Kurosawa, Hiromi; Nagatsu, Masayoshi

    2004-11-01

    A patient with transposition of the great arteries accompanied by Shaher type 9 coronary anatomy experienced the development of progressive neoaortic valvular regurgitation with a small annulus, supravalvular stenosis, and neopulmonary valvular and supravalvular stenoses 15 years after an arterial switch operation. To implant a prosthetic valve clinically adequate in size, the Konno procedure was necessary. However, the right coronary anatomy precluded the original Konno procedure. My colleagues and I accomplished neoaortic anterior annular enlargement in this case by using atrioventricular groove patch plasty without jeopardizing the right coronary artery, and this resulted in a satisfactory outcome.

  18. Manual of procedures for the operation of bench-scale anaerobic digesters

    Energy Technology Data Exchange (ETDEWEB)

    Spencer, R.R.

    1978-12-01

    The successful operation of any laboratory-scale biological system is often a difficult and frustrating experience. This is especially true when dealing with the anaerobic digestion process. Because of the stringent environmental requirements associated with anaerobic digesters, efficient operation of bench-scale units requires rigid monitoring and control. The purpose of this manual is to present the methods and procedures which are followed in bench-scale anaerobic digestion studies at Pacific Northwest Laboratory (PNL). Among the topics discussed are operating parameters, a description of the experimental system, typical digestion substrates, operational procedures, analytical techniques, and safety considerations. The document serves as a technical guide to PNL personnel assigned to a U.S. Department of Energy sponsored program evaluating the effect of powdered activated carbon on the anaerobic digestio of sewage sludge. It should be noted that the methods described in this manual do not necessarily represent the best or only means of conducting the research. They are merely procedures that have been found to be successful at PNL. It is hoped that this information may be useful to other researchers who are contemplating or pursuing bench-scale studies of their own.

  19. Cold and compression in the management of musculoskeletal injuries and orthopedic operative procedures: a narrative review

    Directory of Open Access Journals (Sweden)

    Jon E Block

    2010-07-01

    Full Text Available Jon E BlockJon E Block, PhD., Incorporated, San Francisco, CA, USAAbstract: Cold and compression are routinely applied immediately after acute injury or ­following surgery to alleviate pain, reduce swelling and speed functional recovery. The objective of this literature review is to describe the published clinical findings regarding combined cold and compression therapy in the management of musculoskeletal injuries and after orthopedic operative procedures. Of 33 potential articles triaged, the findings of 21 randomized controlled trials were assessed and summarized. The findings reported by these 21 studies were largely subjective pain outcomes and, to a lesser degree, swelling and range of motion, and were inconsistent and divergent, making it difficult to recommend the most appropriate, effective clinical application of cold and compression. Further, 18 of the 21 reported studies evaluated cold and static compression, where the extent and duration of the compression was not uniform within or across studies. Operative procedures may offer a more controlled environment for rigorous investigations. However, such studies must be powered sufficiently to account for variations in surgical procedure that could affect outcomes. More uniform operative procedures, such as total knee arthroplasty, represent a well circumscribed intervention for studying the clinical utility of cold compression therapy because the operative technique is standardized, surgical tissue damage is extensive, intraoperative blood loss is high, and post-operative edema and pain are severe. Findings from randomized controlled trials of knee arthroplasty generally showed cold compression therapy provides better outcomes such as pain relief than alternative interventions. While the effects of cold and static compression are clearly better than no treatment, they do not appear to be directly additive.Keywords: cryotherapy, injury

  20. The microbial opsin homologue sop1 is involved in Sclerotinia sclerotiorum development and environmental stress response

    Directory of Open Access Journals (Sweden)

    Xueliang eLyu

    2016-01-01

    Full Text Available Microbial opsins play a crucial role in responses to various environmental signals. Here, we report that the microbial opsin gene sop1 in the necrotrophic phytopathogenic fungus Sclerotinia sclerotiorum was dramatically up-regulated during infection and sclerotial development compared with the vegetative growth stage. Further study showed sop1 was essential for growth, sclerotial development and full virulence of S. sclerotiorum. Sop1-silenced transformants were more sensitive to high salt stress, fungicides and high osmotic stress. However, they were more tolerant to oxidative stress compared with the wild-type strain, suggesting that sop1 is involved in different stress responses and fungicide resistance, which plays a role in the environmental adaptability of S. sclerotiorum. Furthermore, a Delta blast search showed that microbial opsins are not present in animals and almost all higher plants, indicating that as a predicted transmembrane protein, sop1 is a potential drug target for disease control of S. sclerotiorum.

  1. 30 CFR 250.172 - When may the Regional Supervisor grant or direct an SOO or SOP?

    Science.gov (United States)

    2010-07-01

    ... direct an SOO or SOP? 250.172 Section 250.172 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT... Suspensions § 250.172 When may the Regional Supervisor grant or direct an SOO or SOP? The Regional Supervisor may grant or direct an SOO or SOP under any of the following circumstances: (a) When necessary...

  2. Evaluating North Carolina Food Pantry Food Safety-Related Operating Procedures.

    Science.gov (United States)

    Chaifetz, Ashley; Chapman, Benjamin

    2015-11-01

    Almost one in seven American households were food insecure in 2012, experiencing difficulty in providing enough food for all family members due to a lack of resources. Food pantries assist a food-insecure population through emergency food provision, but there is a paucity of information on the food safety-related operating procedures used in the pantries. Food pantries operate in a variable regulatory landscape; in some jurisdictions, they are treated equivalent to restaurants, while in others, they operate outside of inspection regimes. By using a mixed methods approach to catalog the standard operating procedures related to food in 105 food pantries from 12 North Carolina counties, we evaluated their potential impact on food safety. Data collected through interviews with pantry managers were supplemented with observed food safety practices scored against a modified version of the North Carolina Food Establishment Inspection Report. Pantries partnered with organized food bank networks were compared with those that operated independently. In this exploratory research, additional comparisons were examined for pantries in metropolitan areas versus nonmetropolitan areas and pantries with managers who had received food safety training versus managers who had not. The results provide a snapshot of how North Carolina food pantries operate and document risk mitigation strategies for foodborne illness for the vulnerable populations they serve. Data analysis reveals gaps in food safety knowledge and practice, indicating that pantries would benefit from more effective food safety training, especially focusing on formalizing risk management strategies. In addition, new tools, procedures, or policy interventions might improve information actualization by food pantry personnel.

  3. Integrated Hatchery Operations Team: Policies and Procedures for Columbia Basin Anadromous Salmonid Hatcheries, 1994 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Integrated Hatchery Operations Team (Northwest Power Planning Council, Portland, OR)

    1995-01-01

    This document outlines regional policies and procedures for hatchery operations in the Columbia River Basin. The purpose of these policies is to provide regional guidelines by which all anadromous fish hatcheries will be operated. These policies will be adopted by the fisheries co-managers, and will provide guidance to operate hatcheries in an efficient and biologically sound manner. The hatchery policies presented in this manual are not intended to establish production priorities. Rather, the intent is to guide hatchery operations once production numbers are established. Hatchery operations discussed in this report include broodstock collection, spawning, incubation of eggs, fish rearing and feeding, fish release, equipment maintenance and operations, and personnel training. Decisions regarding production priorities must be provided by fishery managers through a comprehensive plan that addresses both natural and hatchery fish production. The Integrated Hatchery Operations Team is a multi-agency group called for by the Northwest Power Planning Council. This team was directed to develop new basinwide policies for managing and operating all existing and future anadromous fish hatcheries in the Columbia River Basin. The parties pledge to confer with each other and to use their authorities and resources to accomplish these mutually acceptable hatchery practices.

  4. Test and evaluation procedures for Sandia's Teraflops Operating System (TOS) on Janus.

    Energy Technology Data Exchange (ETDEWEB)

    Barnette, Daniel Wayne

    2005-10-01

    This report describes the test and evaluation methods by which the Teraflops Operating System, or TOS, that resides on Sandia's massively-parallel computer Janus is verified for production release. Also discussed are methods used to build TOS before testing and evaluating, miscellaneous utility scripts, a sample test plan, and a proposed post-test method for quickly examining the large number of test results. The purpose of the report is threefold: (1) to provide a guide to T&E procedures, (2) to aid and guide others who will run T&E procedures on the new ASCI Red Storm machine, and (3) to document some of the history of evaluation and testing of TOS. This report is not intended to serve as an exhaustive manual for testers to conduct T&E procedures.

  5. [Hypospadias with chordee one-stage operation. An original procedure (author's transl)].

    Science.gov (United States)

    Babut, J M; Allouis, M; Paul, J L

    1980-01-01

    The common management of hypospadias involves the chordee correction before reconstructing the urethra; then staging of operative cure is so often necessary. This inconvenience is avoided by neglecting some moderate chordees as it was recorded by the authors in their own retrospective series. For the last two years they are performing a one stage procedure with simultaneous correction of chordee and urethroplasty; they briefly review main other one-stage procedures before describing their own using a tubulated and inverted flap. Twenty cases were managed with this procedure and the results were found satisfactory as well as functionally and aesthetically in spite of three transient fistulas and two meatal stenosis. However, definitive conclusion cannot be drawn because of a too short follow-up.

  6. Routine pre-operative focused ultrasonography by anesthesiologists in patients undergoing urgent surgical procedures

    DEFF Research Database (Denmark)

    Bøtker, M T; Vang, M L; Grøfte, T;

    2014-01-01

    with focused ultrasonography in patients undergoing urgent surgical procedures. Methods We performed pre-operative focused cardiopulmonary ultrasonography in patients aged 18 years or above undergoing urgent surgical procedures at pre-defined study days. Known and unexpected cardiopulmonary pathology...... was recorded, and subsequent changes in the anesthesia technique or supportive actions were registered. Results A total of 112 patients scheduled for urgent surgical procedures were included. Their mean age (standard deviation) was 62 (21) years. Of these patients, 24% were American Society....... Unexpected pathology leading to changes in anesthesia technique or supportive actions was only disclosed in a group of patients above the age of 60 years and/or in ASA class ≥ 3. Conclusion Focused cardiopulmonary ultrasonography disclosed unexpected pathology in patients undergoing urgent surgical...

  7. Rubber dam use during routine operative dentistry procedures: findings from the dental PBRN.

    Science.gov (United States)

    Gilbert, Gregg H; Litaker, Mark S; Pihlstrom, Daniel J; Amundson, Craig W; Gordan, Valeria V

    2013-04-01

    Rubber dam use during operative dentistry procedures has been quantified based on questionnaires completed by dentists. However, based on the knowledge of the authors of the current study, there are no reports based on use during actual clinical procedures other than in dental materials studies and none based on routine care. The objectives of the current study were to: 1) quantify how commonly the rubber dam is used during operative dentistry procedures; 2) test the hypothesis that certain dentist, restoration and patient-level factors are associated with its use. A total of 229 dentist practitioner-investigators in The Dental Practice-Based Research Network (DPBRN) participated. DPBRN comprises 5 regions: Alabama/Mississippi, Florida/Georgia, Minnesota, Permanente Dental Associates; and Scandinavia. Practitioner-investigators collected data on 9,890 consecutive restorations done in previously unrestored tooth surfaces from 5,810 patients. Most dentists (63%) did not use a rubber dam for any restoration in this study. A rubber dam was used for only 12% of restorations, 83% of which were used in 1 DPBRN region. With regions accounted for, no other dentist characteristics were significant. A multi-level multiple logistic regression of rubber dam use was done with restoration and patient-level variables modeled simultaneously. In this multi-variable context, these restoration-level characteristics were statistically significant: tooth-arch type, restoration classification and reason for placing the restoration. These patient-level characteristics were statistically significant: ethnicity, dental insurance, and age. These results, obtained fromactual clinical procedures rather than questionnaires, document a low prevalence of usage of the rubber dam during operative dentistry procedures. Usage varied with certain dentist, restoration, and patient level characteristics.

  8. Rubber dam use during routine operative dentistry procedures: findings from the Dental PBRN.

    Science.gov (United States)

    Gilbert, Gregg H; Litaker, Mark S; Pihlstrom, Daniel J; Amundson, Craig W; Gordan, Valeria V

    2010-01-01

    Rubber dam use during operative dentistry procedures has been quantified based on questionnaires completed by dentists. However, based on the knowledge of the authors of the current study, there are no reports based on use during actual clinical procedures other than in dental materials studies and none based on routine care. The objectives of the current study were to: 1) quantify how commonly the rubber dam is used during operative dentistry procedures; 2) test the hypothesis that certain dentist, restoration and patient-level factors are associated with its use. A total of 229 dentist practitioner-investigators in The Dental Practice-Based Research Network (DPBRN) participated. DPBRN comprises five regions of the USA: Alabama/Mississippi, Florida/Georgia, Minnesota, Permanente Dental Associates and Scandinavia. Practitioner-investigators collected data on 9,890 consecutive restorations done in previously unrestored tooth surfaces from 5,810 patients. Most dentists (63%) did not use a rubber dam for any restoration in this study. A rubber dam was used for only 12% of restorations, 83% of which were used in one DPBRN region. With regions accounted for, no other dentist characteristics were significant. A multi-level multiple logistic regression of rubber dam use was done with restoration and patient-level variables modeled simultaneously. In this multi-variable context, these restoration-level characteristics were statistically significant: tooth-arch type, restoration classification and reason for placing the restoration. These patient-level characteristics were statistically significant: ethnicity, dental insurance and age. These results, obtained from actual clinical procedures rather than questionnaires, document a low prevalence of usage of the rubber dam during operative dentistry procedures. Usage varied with certain dentist, restoration and patient-level characteristics.

  9. Diagnostic hysteroscopy in a procedure room setting compared to diagnostic hysteroscopy in the operating room

    Directory of Open Access Journals (Sweden)

    Ayman Oraif

    2016-12-01

    Conclusions: Diagnostic hysteroscopy is currently considered a valuable investigational tool for endometrial abnormalities and abnormal uterine bleeding. Most of these procedures can be performed in a procedure room setting without I.V. sedation or pre-operative narcotics. In our experience, a utero-sacral block using lidocaine is quite effective in controlling discomfort while passing various instruments through the internal cervical os. These techniques result in good visualization of the endometrial cavity, adequate and appropriate endometrial sampling with tolerable discomfort. The patients spend less time in the hospital, experience a much faster recovery and have less pre-operative restrictions. [Int J Reprod Contracept Obstet Gynecol 2016; 5(12.000: 4164-4173

  10. Refractory Metal Heat Pipe Life Test - Test Plan and Standard Operating Procedures

    Science.gov (United States)

    Martin, J. J.; Reid, R. S.

    2010-01-01

    Refractory metal heat pipes developed during this project shall be subjected to various operating conditions to evaluate life-limiting corrosion factors. To accomplish this objective, various parameters shall be investigated, including the effect of temperature and mass fluence on long-term corrosion rate. The test series will begin with a performance test of one module to evaluate its performance and to establish the temperature and power settings for the remaining modules. The performance test will be followed by round-the-clock testing of 16 heat pipes. All heat pipes shall be nondestructively inspected at 6-month intervals. At longer intervals, specific modules will be destructively evaluated. Both the nondestructive and destructive evaluations shall be coordinated with Los Alamos National Laboratory. During the processing, setup, and testing of the heat pipes, standard operating procedures shall be developed. Initial procedures are listed here and, as hardware is developed, will be updated, incorporating findings and lessons learned.

  11. Procedure for estimating nonfuel operation and maintenance costs for large steam-electric power plants

    Energy Technology Data Exchange (ETDEWEB)

    Myers, M.L.; Fuller, L.C.

    1979-01-01

    Revised guidelines are presented for estimating annual nonfuel operation and maintenance costs for large steam-electric power plants, specifically light-water-reactor plants and coal-fired plants. Previous guidelines were published in October 1975 in ERDA 76-37, a Procedure for Estimating Nonfuel Operating and Maintenance Costs for Large Steam-Electric Power Plants. Estimates for coal-fired plants include the option of limestone slurry scrubbing for flue gas desulfurization. A computer program, OMCOST, is also presented which covers all plant options.

  12. Measurement of spatial dose distribution for evaluation operator dose during nero-interventional procedures

    Energy Technology Data Exchange (ETDEWEB)

    Han, Su Chul [Division of Medical Radiation Equipment, Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of); Hong, Dong Hee [Dept. of Radiology Science, Far East University, Eumseong (Korea, Republic of)

    2016-09-15

    The spatial dose distribution was measured with ionization chamber as preliminary study to evaluate operator dose and to study dose reduction during neuro-interventional procedures. The zone of operators was divided into four area (45, 135, 225, and 315 degree).We supposed that operator exist on the four area and indicated location of critical organs(eyes, breast, gonad). The spatial doses were measured depending on distance( 80, 100, 120, and 140 cm) and location of critical organs. The spatial doses of area of 225 degree were 114.5 mR/h (eyes location), 143.1 mR/h (breast location) and 147 mR/h (gonad location) in 80 cm. When changed location of x-ray generator, spatial dose increased in 18.1±10.5%, averagely. We certified spatial dose in the operator locations, Using the results of this study, It is feasible to protect operator from radiation in neuro-interventional procedures.

  13. What is a Bristow-Latarjet procedure? A review of the described operative techniques and outcomes.

    Science.gov (United States)

    Cowling, P D; Akhtar, M A; Liow, R Y L

    2016-09-01

    A variety of operative techniques have been described as under the term 'Bristow-Latarjet' procedure. This review aims to define the original procedure, and compare the variation in techniques described in the literature, assessing any effect on clinical outcomes. A systematic review of 24 studies was performed to compare specific steps of the technique (coracoid osteotomy site, subscapularis approach, orientation and position of coracoid graft fixation and fixation method, additional labral and capsular repair) and detect any effect this variability had on outcomes. Overall recurrence rate was 5.36% (2.94% to 43%). Half of the studies performed the procedure for recurrent shoulder instability, with only five studies documenting glenoid bone loss as an indication: 12 studies used the procedure as the primary surgical intervention for recurrent instability. No change in outcome was noted when examining variation in the coracoid osteotomy site, the fixation site on the scapular neck, the fixation method or whether a capsular repair was also performed. Performing a horizontal split in subscapularis may preserve external rotation compared with performing a tenotomy. This is the first review to examine various operative techniques of the Bristow-Latarjet procedure, and their effect on outcome. We found that other than the approach through subscapularis, outcome was independent of the surgical technique, and depended more on patient selection. We would commend future publications on this procedure to provide a detailed description of the surgical technique, and as a minimum present rates of recurrence as an outcome measure. Cite this article: Bone Joint J 2016;98-B:1208-14. ©2016 The British Editorial Society of Bone & Joint Surgery.

  14. 2014 Update of the EULAR standardised operating procedures for EULAR-endorsed recommendations.

    Science.gov (United States)

    van der Heijde, Désirée; Aletaha, Daniel; Carmona, Loreto; Edwards, Christopher J; Kvien, Tore K; Kouloumas, Marios; Machado, Pedro; Oliver, Sue; de Wit, Maarten; Dougados, Maxime

    2015-01-01

    In this article, the European League Against Rheumatism (EULAR) standardised operating procedures for the elaboration, evaluation, dissemination and implementation of recommendations endorsed by the EULAR standing committees published in 2004 have been updated. The various steps from the application to implementation have been described in detail. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  15. Cold and compression in the management of musculoskeletal injuries and orthopedic operative procedures: a narrative review

    OpenAIRE

    2010-01-01

    Jon E BlockJon E Block, PhD., Incorporated, San Francisco, CA, USAAbstract: Cold and compression are routinely applied immediately after acute injury or ­following surgery to alleviate pain, reduce swelling and speed functional recovery. The objective of this literature review is to describe the published clinical findings regarding combined cold and compression therapy in the management of musculoskeletal injuries and after orthopedic operative procedures. Of 33 potential articles tr...

  16. Benchmarking an operational procedure for rapid flood mapping and risk assessment in Europe

    Science.gov (United States)

    Dottori, Francesco; Salamon, Peter; Kalas, Milan; Bianchi, Alessandra; Feyen, Luc

    2016-04-01

    The development of real-time methods for rapid flood mapping and risk assessment is crucial to improve emergency response and mitigate flood impacts. This work describes the benchmarking of an operational procedure for rapid flood risk assessment based on the flood predictions issued by the European Flood Awareness System (EFAS). The daily forecasts produced for the major European river networks are translated into event-based flood hazard maps using a large map catalogue derived from high-resolution hydrodynamic simulations, based on the hydro-meteorological dataset of EFAS. Flood hazard maps are then combined with exposure and vulnerability information, and the impacts of the forecasted flood events are evaluated in near real-time in terms of flood prone areas, potential economic damage, affected population, infrastructures and cities. An extensive testing of the operational procedure is carried out using the catastrophic floods of May 2014 in Bosnia-Herzegovina, Croatia and Serbia. The reliability of the flood mapping methodology is tested against satellite-derived flood footprints, while ground-based estimations of economic damage and affected population is compared against modelled estimates. We evaluated the skill of flood hazard and risk estimations derived from EFAS flood forecasts with different lead times and combinations. The assessment includes a comparison of several alternative approaches to produce and present the information content, in order to meet the requests of EFAS users. The tests provided good results and showed the potential of the developed real-time operational procedure in helping emergency response and management.

  17. Short Operative Duration and Surgical Site Infection Risk in Hip and Knee Arthroplasty Procedures.

    Science.gov (United States)

    Dicks, Kristen V; Baker, Arthur W; Durkin, Michael J; Anderson, Deverick J; Moehring, Rebekah W; Chen, Luke F; Sexton, Daniel J; Weber, David J; Lewis, Sarah S

    2015-12-01

    To determine the association (1) between shorter operative duration and surgical site infection (SSI) and (2) between surgeon median operative duration and SSI risk among first-time hip and knee arthroplasties. Retrospective cohort study A total of 43 community hospitals located in the southeastern United States. Adults who developed SSIs according to National Healthcare Safety Network criteria within 365 days of first-time knee or hip arthroplasties performed between January 1, 2008 and December 31, 2012. Log-binomial regression models estimated the association (1) between operative duration and SSI outcome and (2) between surgeon median operative duration and SSI outcome. Hip and knee arthroplasties were evaluated in separate models. Each model was adjusted for American Society of Anesthesiology score and patient age. A total of 25,531 hip arthroplasties and 42,187 knee arthroplasties were included in the study. The risk of SSI in knee arthroplasties with an operative duration shorter than the 25th percentile was 0.40 times the risk of SSI in knee arthroplasties with an operative duration between the 25th and 75th percentile (risk ratio [RR], 0.40; 95% confidence interval [CI], 0.38-0.56; P<.01). Short operative duration did not demonstrate significant association with SSI for hip arthroplasties (RR, 1.04; 95% CI, 0.79-1.37; P=.36). Knee arthroplasty surgeons with shorter median operative durations had a lower risk of SSI than surgeons with typical median operative durations (RR, 0.52; 95% CI, 0.43-0.64; P<.01). Short operative durations were not associated with a higher SSI risk for knee or hip arthroplasty procedures in our analysis.

  18. Systematic procedure for generating operational policies to achieve target crystal size distribution (CSD) in batch cooling crystallization

    DEFF Research Database (Denmark)

    Abdul Samad, Noor Asma Fazli; Singh, Ravendra; Sin, Gürkan

    2011-01-01

    A systematic procedure to achieve a target crystal size distribution (CSD) under generated operational policies in batch cooling crystallization is presented. An analytical CSD estimator has been employed in the systematic procedure to generate the necessary operational policies to achieve the ta...

  19. Classifier-ensemble incremental-learning procedure for nuclear transient identification at different operational conditions

    Energy Technology Data Exchange (ETDEWEB)

    Baraldi, Piero, E-mail: piero.baraldi@polimi.i [Dipartimento di Energia - Sezione Ingegneria Nucleare, Politecnico di Milano, via Ponzio 34/3, 20133 Milano (Italy); Razavi-Far, Roozbeh [Dipartimento di Energia - Sezione Ingegneria Nucleare, Politecnico di Milano, via Ponzio 34/3, 20133 Milano (Italy); Zio, Enrico [Dipartimento di Energia - Sezione Ingegneria Nucleare, Politecnico di Milano, via Ponzio 34/3, 20133 Milano (Italy); Ecole Centrale Paris-Supelec, Paris (France)

    2011-04-15

    An important requirement for the practical implementation of empirical diagnostic systems is the capability of classifying transients in all plant operational conditions. The present paper proposes an approach based on an ensemble of classifiers for incrementally learning transients under different operational conditions. New classifiers are added to the ensemble where transients occurring in new operational conditions are not satisfactorily classified. The construction of the ensemble is made by bagging; the base classifier is a supervised Fuzzy C Means (FCM) classifier whose outcomes are combined by majority voting. The incremental learning procedure is applied to the identification of simulated transients in the feedwater system of a Boiling Water Reactor (BWR) under different reactor power levels.

  20. Standard operating procedure: use in nursing care in hospital services Procedimiento operacional estándar: utilización en la asistencia de enfermería en servicios hospitalarios Procedimento operacional padrão: utilização na assistência de enfermagem em serviços hospitalares

    Directory of Open Access Journals (Sweden)

    Giselle Patrícia Guerrero

    2008-12-01

    Full Text Available This is a descriptive and quantitative study, carried out in three hospitals in the Northwest of São Paulo, Brazil. It aimed to verify the existence and use of Standard Operating Procedures (SOP by nursing teams. SOPs describe each critical and sequential step of a task to ensure its expected result. A total of 261 nursing professionals participated in the study, randomly selected from different units and shifts between August and September 2006. Results indicate that 56.7% use SOPs only when they have doubts; 54.02% of the nursing technicians and auxiliaries and 62.86% of nurses do not believe the procedures are being complied with. These findings indicate the need for continuing training on SOP use and compliance by all professionals, with a view to improving nursing care.Se trata de un estudio descriptivo con abordaje cuantitativa, realizado en 3 instituciones hospitalarias en el noroeste del estado de San Pablo, con los objetivos principales de verificar la existencia y la utilización, por el equipo de enfermería, de los Procedimientos Operacionales Estándar (POEs, desarrollados a fin de describir cada paso crítico y secuencial para garantizar el resultado esperado de una tarea. Participaron, de forma aleatoria, 261 profesionales de enfermería de diversas unidades de internación en los distintos turnos, entre los meses de agosto y septiembre de 2006. Se verificó que 56,7% acceden a los POE solamente cuando tienen dudas; 54,02% de los técnicos y auxiliares y 62,86% de los enfermeros no creen en el seguimiento de los POE. Esos valores llevan a reflexionar sobre la necesidad de ofrecer entrenamientos continuos en relación a la utilización y seguimiento de los POE por todos los profesionales, a fin de mejorar la asistencia de enfermería.Trata-se de estudo descritivo com abordagem quantitativa, realizado em 3 instituições hospitalares do noroeste paulista, com os objetivos principais de verificar a existência e a utilização pela

  1. Doses to operators during interventional radiology procedures: focus on eye lens and extremity dosimetry.

    Science.gov (United States)

    Koukorava, C; Carinou, E; Simantirakis, G; Vrachliotis, T G; Archontakis, E; Tierris, C; Dimitriou, P

    2011-03-01

    The present study is focused on the personnel doses during several types of interventional radiology procedures. Apart from the use of the official whole body dosemeters (thermoluminescence dosemeter type), measurements were performed to the extremities and the eyes using thermoluminescent loose pellets. The mean doses per kerma area product were calculated for the monitored anatomic regions and for the most frequent types of procedures. Higher dose values were measured during therapeutic procedures, especially embolisations. The maximum recorded doses during a single procedure were 1.8 mSv to the finger (nephrostomy), 2.1 mSv to the wrist (liver chemoembolisation), 0.6 mSv to the leg (brain embolisation) and 2.4 mSv to the eye (brain embolisation). The annual doses estimated for the operator with the highest workload according to the measurements and the system's log book were 90.4 mSv to the finger, 107.9 mSv to the wrist, 21.6 mSv to the leg and 49.3 mSv to the eye. Finally, the effect of the beam angulation (i.e. projection) and shielding equipment on the personnel doses was evaluated. The measurements were performed within the framework of the ORAMED (Optimization of RAdiation Protection for MEDical staff) project.

  2. Experimental Study ofa New Operative Procedure for Non-Ischemic Dilated Cardiomyopathy-Overlapping Cardiac Volume Reduction Operation

    Institute of Scientific and Technical Information of China (English)

    罗滨; 孟春营; 温定国; 松居喜朗; 安田庆秀

    2003-01-01

    Objectives To assess anewly devised procedure of cardiac volume reduction without resection of cardiac muscle and evaluated in experimental settings. Methods Ten beagle dogs underwent a rapid pacing leading to heart failure for 3 weeks and received the left ventricular reduction termed overlapping cardiac volume reduction operation (OLCVR) ,which consisted of a longitudinal incision in left ventricular (LV) free wall, sutures of the left marginal to the septal wall, and the right marginal to LV free wall.A slope of the linear preload recruitable stroke work relationship (Mw) , with a X - intercept (Vo) were calculated as the precise indicators of left ventricular systolic function. The constant of isovolumic pressure decay (Tau) and a peak filling rate (PFR) were also calculated as the indicators of LV diastolic function.Results LV end- diastolic dimensions was significantly reduced by OLCVR (43±2 to 25±1; mm).Fractional shortening was significantly improved by OLCVR (11±2 to 30±4;%). Mw (erg* cm-3* 103)was also significantly improved (21±2 to 33 ±3 (p<0. 001 ) ) , whereas Vo, Tau and PFR did not show significant changes. Conclusions The OLCVR significantly increased in the early LV systolic function without detrimental effects on diastolic function. This procedure may become a therapeutic option for end - stage cardiomyopathy.

  3. Modelo quantitativo para avaliação e melhoria de desempenho do processo de S&OP baseado no diagnóstico e redução de falhas A quantitative model for the assessment and performance improvement of S&OP process based on the diagnosis and reduction of failures

    Directory of Open Access Journals (Sweden)

    Fabio José Pandim

    2012-01-01

    Full Text Available O processo de Sales and Operations Planning - Planejamento de Vendas e Operações (S&OP, assim como qualquer processo de nível estratégico ou tático, necessita ter o seu desempenho monitorado para que seja possível realizar ações de melhoria nos aspectos que estejam gerando impactos negativos em seu desempenho. Os modelos para análise de desempenho encontrados na literatura não trazem meios para localizar as causas de ineficiência mais relevantes, quando da utilização de processos S&OP, bem como não fornecem uma maneira de se quantificar o desempenho do processo. Com o objetivo de contribuir com esta necessidade, o presente trabalho apresenta um modelo quantitativo para análise e melhoria de desempenho do processo de S&OP baseado no diagnóstico e na redução de suas ineficiências mais importantes.The S&OP process, like any business process of strategic or tactical level, requires having its performance measured so that, through the monitoring of these measurements, improvement actions for the factors affecting their performance can be created. The models for performance analysis in the literature failed to identify the most relevant causes of inefficiency to the process and do provide a way of measuring the process performance. Therefore, this paper presents a proposal for a quantitative model for the analysis and performance improvement of the S&OP process based on the diagnosis and reduction of its most important inefficiencies.

  4. LIGHTWEIGHT VIGILANT PROCEDURE TO IMPLEMENT SECURITY MEASURES IN HIGHLY ROVING MILITARY OPERATIONS

    Directory of Open Access Journals (Sweden)

    J. Udhayan

    2013-01-01

    Full Text Available The performance of Mobile Ad hoc Network (MANET becomes questionable in highly roving and mission critical application like military operation. Security measures like encryption, authentication, digital signature has been proposed for MANET. However all those mechanisms need some kind of static infrastructure and it is extremely difficult to implement such an infrastructure throughout the military mission. Therefore in this work, various zones in military operation is identified and Zone A is responsible for implementing robust security measures, Zone B and Zone C are identified to be at highly hostile and time critical environment. Therefore usage of highly complex security procedures at zone B & C may delay the operation to the extent of failure of the mission. Hence in this study, a lightweight vigilant procedure that suits the circumstances of Zone B & C is proposed, it has the capability of detecting the malicious entrant in the routing path. Moreover, it works either independently or dependently with the routing protocols like AODV based on the need. The proposed method has been compared with various successful security measures in Ad-hoc network and the results shows that the proposed method is very useful in adapting to the conditions of zone B & C.

  5. Development of manufacturing and operating procedure for fabrication of DUPIC fuel

    Energy Technology Data Exchange (ETDEWEB)

    Park, Geun Il; Lee, J. W.; Kim, S. S. [and others

    2003-01-01

    The manual of Manufacturing and Operating Procedure (MOP) for the fabrication of DUPIC fuel with high quality was developed based on quality assurance program with CAN3-Z299.2-85 to the extent as needed and appropriate. This manual describes a series of fabrication processes that can be applied to fabricate the DUPIC fuel and element, which cover the slitting process, powder fabrication with improved sinterability, milling and sintering processes conducted in DFDF. The qualification tests for establishing the optimal process conditions of DUPIC fuel fabrication were carried out with various process conditions such as pressing pressure. This MOP was revised twice with the support of qualification test results and a specified procedure.

  6. An ergonomics study of computerized emergency operating procedures: Presentation style, task complexity, and training level

    Energy Technology Data Exchange (ETDEWEB)

    Xu Song; Song Fei [Department of Industrial Engineering, Tsinghua University, Beijing 100084 (China); Li Zhizhong [Department of Industrial Engineering, Tsinghua University, Beijing 100084 (China)], E-mail: zzli@tsinghua.edu.cn; Zhao Qianyi; Luo Wei [Department of Industrial Engineering, Tsinghua University, Beijing 100084 (China); He Xuhong [Scanpower Risk Management China Inc., Towercrest International Plaza, No. 3 Maizidian West Road, Chaoyang District, Beijing 100016 (China); Salvendy, Gavriel [Department of Industrial Engineering, Tsinghua University, Beijing 100084 (China)

    2008-10-15

    Emergency operating procedures (EOPs) are widely used in nuclear power plants (NPPs). With the development of information technology, computerized EOPs are taking the place of paper-based ones. Unlike paper-based EOPs, the industrial practice of computerized EOPs is still quite limited. Ergonomics issues of computerized EOPs have not been studied adequately. This study focuses on the effects of EOP presentation style, task complexity, and training level on the performance of the operators in the execution of computerized EOPs. One simulated computerized EOP system was developed to present two EOPs, each with different task complexity levels, by two presentation styles (Style A: one- and two-dimensional flowcharts combination; Style B: two-dimensional flowchart and success logic tree combination). Forty subjects participated in the experiment of EOP execution using the simulated system. Statistical analysis of the experimental results indicates that: (1) complexity, presentation style, and training level all can significantly influence the error rate. High-complexity tasks and lack of sufficient training may lead to a higher error rate. Style B caused a significantly higher error rate than style A did in the skilled phase. So the designers of computerized procedures should take the presentation styles of EOPs into account. (2) Task complexity and training level can significantly influence operation time. No significant difference was found in operation time between the two presentation styles. (3) Training level can also significantly influence the subjective workload of EOPs operations. This implies that adequate training is very important for the performance of computerized EOPs even if emergency responses with computerized EOPs are much more simple and easy than that with paper-based EOPs.

  7. [Choice of surgical procedure in operations for chronic pancreatitis--personal experience].

    Science.gov (United States)

    Sváb, J; Pesková, M; Fried, M; Gürlich, R; Krska, Z; Bortlík, M; Lukás, M; Horejs, J

    2002-01-01

    The First Surgical Clinic of the First Medical Faculty of Charles University and General Faculty Hospital in Prague made operations of the pancreas ever since 1971. In the work sooner or later all approaches to surgical treatment pancreatitis were reflected. The authors present a brief review of results and their own experience since 1994 when duodenum-sparing operations were introduced. Indications for surgical treatment were based on the diagnosis by US, CT and ERCP, in exceptional case MR, after evaluation by a pancreatologist, roentgenologist and surgeon. The group of patients with chronic pancreatitis was extended by 21 patients from a group operated because of preoperative suspicion of a malignant pancreatic tumour not confirmed during and after surgery. In those Whipple's operation was preformed. The same operation was performed in three patients with chronic pancreatitis with serious changes in the area of the head of the pancreas. In 123 patients a drainage and duodenum sparing operation was preformed, of these in 57 according to Beger, 19 according to Frey, 37 Partington-Rochelle's procedure. The authors record two sepsis postoperative complications after the classical Beger operation and the hospital stay was on average by five days shorter as compared with the classical method of Whipple. When evaluating postoperative complaints and problems (pain, malnutrition, physical constitution and social position) the authors recorded equally favourable results as after non-complicated duodenopancreatectomy. They varied, depending on the patients co-operation round 84-87% while authors consider Beger's operation logical because of the removal of the main tissue mass of the head of the pancreas, responsible for pain, complications caused by fibrosis in the area round the bile duct and duodenum, responsible for the deteriation of the compartment syndrome in the left half of the gland. Its result is destruction of the remainder of exocrine and endocrine tissue. Of

  8. Operating Procedure Changes to Improve Antiproton Production at the Fermilab Tevatron Collider

    Energy Technology Data Exchange (ETDEWEB)

    Drendel, B.; Morgan, J.P.; Vander Meulen, D.; /Fermilab

    2009-04-01

    Since the start of Fermilab Collider Run II in 2001, the maximum weekly antiproton accumulation rate has increased from 400 x 10{sup 10} Pbars/week to approximately 3,700 x 10{sup 10} Pbars/week. There are many factors contributing to this increase, one of which involves changes to operational procedures that have streamlined and automated Antiproton Source production. Automation has been added to the beam line orbit control, stochastic cooling power level management, and RF settings. In addition, daily tuning efforts have been streamlined by implementing sequencer driven tuning software.

  9. Test Operations Procedure (TOP) 02-2-820 Tactical Vehicle Climate Control Testing

    Science.gov (United States)

    2017-03-31

    Final 3. DATES COVERED (From - To) 4. TITLE AND SUBTITLE Test Operations Procedure (TOP) 02-2-820 Tactical Vehicle Climate Control Testing 5a...ORGANIZATION NAME(S) AND ADDRESS(ES) U.S. Army Aberdeen Test Center ATTN: TEDT-AT-ADI 400 Colleran Road Aberdeen Proving Ground, MD 21005-5059 8...U.S. Army Test and Evaluation Command 2202 Aberdeen Boulevard Aberdeen Proving Ground, MD 21005-5001 10. SPONSOR/MONITOR’S ACRONYM(S) 11

  10. Operational circular No.10 – Principles and procedures governing investigation of fraud

    CERN Multimedia

    2013-01-01

    Operational Circular No. 10 entitled “Principles and procedures governing investigation of Fraud”, approved by the Director-General following discussion at the Standing Concertation Committee meeting of 4 December 2012 and entering into force on 1 January 2013, is available on the intranet site of the Human Resources Department.   This circular is applicable to all persons working at or on behalf of CERN. The purpose of this new operational circular is to specify the definition of fraud and to lay down the Organization’s fraud investigation process pursuant to the CERN Anti-fraud Policy and in accordance with the principles of due process. Department Head Office HR Department

  11. Behavioral observations and operant procedures using microwaves as a heat source for young chicks

    Energy Technology Data Exchange (ETDEWEB)

    Morrison, W.D.; McMillan, I.; Bate, L.A.; Otten, L.; Pei, D.C.

    1986-08-01

    Four trials, using operant conditioning procedures, were conducted to study the response of chicks, housed at 16 C, to microwave or infrared heat. Microwave power density was 26 mW/cm2 in Trial 1, 13 mW/cm2 in Trial 2, and 10 mW/cm2 in Trials 3 and 4. Chicks voluntarily demanded between 28 and 63% as much heat (min heat/hr) from microwave source as from infrared source at all power densities. There was no correlation, however, between the ratio of heat demanded and the power density used. There were no significant differences in growth between infrared- or microwave-heated chicks. It is evident from these studies that 8-day-old broiler chicks are capable of associating the performance of a task with a thermal reward provided by the microwaves. They are also able to utilize these microwaves through operant conditioning without any visible detrimental effect to their health or behavior.

  12. 40 CFR Appendix K to Part 75 - Quality Assurance and Operating Procedures for Sorbent Trap Monitoring Systems

    Science.gov (United States)

    2010-07-01

    ... Pump. Use a leak-tight, vacuum pump capable of operating within the candidate system's flow range. 5.1... sorbent trap monitoring system typically operates. The gas flow meter shall be equipped with any necessary... system typically operates. You may either follow the procedures in section 10.3.1 of Method 5 in...

  13. Influence of step complexity and presentation style on step performance of computerized emergency operating procedures

    Energy Technology Data Exchange (ETDEWEB)

    Xu Song [Department of Industrial Engineering, Tsinghua University, Beijing 100084 (China); Li Zhizhong [Department of Industrial Engineering, Tsinghua University, Beijing 100084 (China)], E-mail: zzli@tsinghua.edu.cn; Song Fei; Luo Wei; Zhao Qianyi; Salvendy, Gavriel [Department of Industrial Engineering, Tsinghua University, Beijing 100084 (China)

    2009-02-15

    With the development of information technology, computerized emergency operating procedures (EOPs) are taking the place of paper-based ones. However, ergonomics issues of computerized EOPs have not been studied adequately since the industrial practice is quite limited yet. This study examined the influence of step complexity and presentation style of EOPs on step performance. A simulated computerized EOP system was developed in two presentation styles: Style A: one- and two-dimensional flowcharts combination; Style B: two-dimensional flowchart and success logic tree combination. Step complexity was quantified by a complexity measure model based on an entropy concept. Forty subjects participated in the experiment of EOP execution using the simulated system. The results of data analysis on the experiment data indicate that step complexity and presentation style could significantly influence step performance (both step error rate and operation time). Regression models were also developed. The regression analysis results imply that operation time of a step could be well predicted by step complexity while step error rate could only partly predicted by it. The result of a questionnaire investigation implies that step error rate was influenced not only by the operation task itself but also by other human factors. These findings may be useful for the design and assessment of computerized EOPs.

  14. [Sop proteins can cause transcriptional silencing of genes located close to the centromere sites of linear plasmid N15].

    Science.gov (United States)

    Mardanov, A V; Lane, D; Ravin, N V

    2010-01-01

    Stable inheritance of bacterial chromosomes and low copy number plasmids is ensured by accurate partitioning of replicated molecules between the daughter cells at division. Partitioning of the prophage of the temperate bacteriophage N15, which exists as a linear plasmid molecule with covalently closed ends, depends on the sop locus, comprising genes sopA and sopB, as well as four centromere sites located in different regions of the N15 genome essential for replication and the control of lysogeny. We found that binding of SopB to the centromere can silence centromere-proximal promoters, presumably due to subsequent polymerizing of SopB along the DNA. Close to the IR4 centromere site we identified a promoter, P59, able to drive expression of phage late genes encoding the structural proteins of virion. We found that following binding to IR4 the N15 Sop proteins can cause repression of this promoter. The repression depends on SopB and became stronger in the presence of SopA. Sop-dependent silencing of centromere-proximal promoters control gene expression in phage N15, particularly preventing undesired expression of late genes in the N15 prophage. Thus, the phage N15 sop system not only ensures plasmid partitioning but is also involved in the genetic network controlling prophage replication and the maintenance of lysogeny.

  15. Visibility in magnetostrictive fiber-optic interferometric sensors and its dependence on the input SOP

    Institute of Scientific and Technical Information of China (English)

    Changhai Shi; Jianping Chen; Xinwan Li; Ailun Ye; Junhe Zhou; Yi Zhang; Qing Xue; Lin Hong

    2006-01-01

    The visibility in magnetostrictive fiber-optic interferometric sensors using a Gaussian laser beam is analyzed. It is shown that the conventional Gaussian laser beam has little influence on the visibility. The visibility depends strongly on the input state of polarization (SOP). We implement a cylindrical transducer and build a measurement setup with a polarization controller. The visibility dependent on the SOP of input light is measured. The estimated values are similar to the experiment results, which verifies the analysis.

  16. On Medical Risk Emergency Disposal Technology SOP in China%论我国医疗风险应急处置技术SOP

    Institute of Scientific and Technical Information of China (English)

    姜鑫; 霍原; 张赫楠

    2014-01-01

    医疗风险应急处置技术是现代社会医疗风险管理体系中非常重要的环节,其规范性与科学性对于医疗风险应急处置技术的效果至关重要。文章围绕医疗风险应急处置技术SOP展开阐述,界定了医疗风险及应急处置技术SOP,重点阐述医疗风险应急处置技术SOP的内容,从明确相关定义、组织体系及职责、应急处置预案、处置技术流程、责任追究等方面进行了论证,目的是构建科学的医疗风险应急处置技术SOP,以期更好地实现医疗风险的科学、有序处置。%Emergency disposal technology of medical risks is a very important part of modern social medical risk management system, its standardization and scientificity is essential to the effect of the emergency disposal technology of medical risks. The article discusses medical risk emergency disposal technology SOP, defines the concept of medical risk and emergency disposal technology SOP,focuses on the content of medical risk emergen-cy disposal technology SOP, demonstrates from the aspects of clear definition, organizational system and function, emergency response plans, disposal technology process, and accountability, with the purpose of building a scien-tific SOP for emergency disposal technology of medical risks, and better implementing scientific and orderly dis-position of medical risks.

  17. Task Analysis of Emergency Operating Procedures for Generating Quantitative HRA Data

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Yochan; Park, Jinkyun; Kim, Seunghwan; Choi, Sun Yeong; Jung, Wondea; Jang, Inseok [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    In this paper, the analysis results of the emergency task in the procedures (EOPs; emergency operating procedures) that can be observed from the simulator data are introduced. The task type, component type, system type, and additional information related with the performance of the operators were described. In addition, a prospective application of the analyzed information to HEP quantification process was discussed. In the probabilistic safety analysis (PSA) field, various human reliability analyses (HRAs) have been performed to produce estimates of human error probabilities (HEPs) for significant tasks in complex socio-technical systems. To this end, Many HRA methods have provided basic or nominal HEPs for typical tasks and the quantitative relations describing how a certain performance context or performance shaping factors (PSFs) affects the HEPs. In the HRA community, however, the necessity of appropriate and sufficient human performance data has been recently indicated. This is because a wide range of quantitative estimates in the previous HRA methods are not supported by solid empirical bases. Hence, there have been attempts to collect HRA supporting data. For example, KAERI has started to collect information on both unsafe acts of operators and the relevant PSFs. A characteristic of the database that is being developed at KAERI is that human errors and related PSF surrogates that can be objectively observable are collected from full-scope simulator experiences. In this environment, to produce concretely grounded bases of the HEPs, the traits or attributes of tasks where significant human errors can be observed should be definitely determined. The determined traits should be applicable to compare the HEPs on the traits with the data in previous HRA methods or databases. In this study, task characteristics in a Westinghouse type of EOPs were analyzed with the defining task, component, and system taxonomies.

  18. Investigations into the efficacy of different procedures for surgical hand disinfection between consecutive operations.

    Science.gov (United States)

    Rehork, B; Rüden, H

    1991-10-01

    In order to examine whether thorough surgical hand disinfection (handwashing plus hand disinfection) between consecutive operations is necessary, tests were carried out simulating normal clinical conditions. The tests were performed according to the guidelines for the evaluation of disinfection procedures of the German Society for Hygiene and Microbiology. Surgical hand disinfection was as follows: handwashing with soap without antimicrobial additives and subsequent 5-min disinfection with 60% n-propanol. This was followed by simulated operations of 30 or 120 min duration with a 30-min break between operations, during which half of the test group kept on the surgical gloves, while the other half removed them. The second surgical hand disinfection was done without prior handwashing by 50% of the test group. The disinfection time was reduced from 5 to 1 min by 50% of the test group. The results were evaluated by means of explorative data analysis and inductive statistical methods. Removing the surgical gloves during the interoperative break did not result in significantly higher numbers of colony forming units (cfu) compared with retaining the gloves. This was also the case after a subsequent handwashing. At the second surgical hand disinfection, after a simulated operation of 60 min duration (including break), there was no significant difference in the numbers of cfus between the test group who had washed their hands and those who had not. Reducing the disinfection time from 5 min to 1 min was not associated with a significant increase in the number of cfus. However, after a simulated operating time of 150 min (including the break), the second surgical hand disinfection with handwashing resulted in a significantly lower number of microorganisms than disinfection alone. In half the tests, the numbers of cfu were significantly lower when the test group disinfected their hands for 5 min rather than 1 min.

  19. A statewide consortium of surgical care: a longitudinal investigation of vascular operative procedures at 16 hospitals.

    Science.gov (United States)

    Henke, Peter K; Kubus, Jim; Englesbe, Michael J; Harbaugh, Calista; Campbell, Darrell A

    2010-10-01

    Regional surgical quality improvement consortiums are becoming more common. Herein we have reported the effectiveness of a statewide consortium focusing on open vascular operative procedures. The statewide Michigan Surgical Quality Consortium was established in 2005 with 16 hospitals that report cases of vascular open operative intervention, in a sampling manner consistent with the private sector National Surgical Quality Improvement Program. Data are abstracted by onsite trained nurses using defined and validated pre-, peri-, and postoperative variables with 30-day follow-up. Outpatient and emergent cases were excluded. We compared outcomes over the course of the consortium (era I, April 2005-March 2007; era II, April 2007-March 2008) via univariate and multivariate techniques. Era I (n = 2,453) and era II (n = 3,409) cases were similar in age (mean, 68 years), gender (61% male), relative value units (mean, 21), and distribution of Current Procedural Terminology codes. Duration of stay and operative time decreased by 15% and 11%, respectively, when comparing era I with era II (P cardiac or renal, complications. When evaluating both eras, modifiable variables (able to be altered by the surgeon) for morbidity included increased length of operation (odds ratio [OR], 1.004; 95% confidence interval [CI], 1.003-1.005; P < .0001), hypertension (OR, 1.46; 95% CI, 1.03-2.1; P = .03), and blood transfusion (OR, 2.8; 95% CI, 2.04-3.88; P < .0001). However, anemic patients (11%; hematocrit <30) who were transfused were less likely to suffer morbidity (OR, 56; 95% CI, 0.47-0.67; P < .0001) than those transfused who were not anemic. The absolute 2% reduction in complications led to a $172 cost savings for the payers per patient in era II compared with era I. A statewide quality-of-care consortium with timely feedback of data was associated with decreased morbidity over a relatively short follow-up period in vascular patients. Focusing on best processes in real-world practice

  20. Minor elective surgical procedures using general anesthesia in children with sickle cell anemia without pre-operative blood transfusion.

    Science.gov (United States)

    Fu, Teresa; Corrigan, Nicole J; Quinn, Charles T; Rogers, Zora R; Buchanan, George R

    2005-07-01

    Pre-operative red blood cell (RBC) transfusions are often recommended for patients with sickle cell disease (SCD) who require elective surgery under general anesthesia. However, definitive randomized studies demonstrating the benefit of transfusions in this setting have not been conducted. In particular, the merits of transfusion prior to minor or low-risk surgical procedures in children with SCD have not been demonstrated. We hypothesized that children with sickle cell anemia (Hb SS) who have minor elective surgical procedures develop few complications even without pre-operative transfusion. We accessed our Comprehensive Sickle Cell Program's Database to identify all such procedures performed during a 13-year period. Medical records were reviewed to characterize the surgical procedure, the use of transfusions, and perioperative complications. Twenty-eight children with Hb SS had a total of 38 minor surgical procedures. No perioperative transfusions were given in 34 of the cases (85%). Five of these 34 surgeries (15%) were associated with minor post-operative complications (fever or transient pain). No post-operative acute chest syndrome was encountered. Minor or low-risk elective surgical procedures in children with Hb SS may not routinely require pre-operative transfusion. A randomized clinical trial to compare transfusion with no transfusion for minor surgical procedures is needed.

  1. A Heuristic Procedure for the Outbound Container Relocation Problem during Export Loading Operations

    Directory of Open Access Journals (Sweden)

    Roberto Guerra-Olivares

    2015-01-01

    Full Text Available During export ship loading operations, it is often necessary to perform relocation movements with containers that interfere with access to the desired container in the ship loading sequence. This paper presents a real-time heuristic procedure for the container relocation problem employing reachstacker vehicles as container handling equipment. The proposed heuristic searches for good relocation coordinates within a set of nearby bays. The heuristic has a parameter that determines how far from the original bay a container may be relocated. The tradeoff between reducing relocation movements and limiting vehicle travel distances is examined and the performance of the heuristic is compared with a common practice in the smaller container terminals in Chile and Mexico. Finally, a mathematical model for the container relocation problem is presented.

  2. Standardization of the Action Verbs used in Emergency Operating Procedures of NPPs

    Energy Technology Data Exchange (ETDEWEB)

    Jang, Tong Il; Lee, Yong Hee; Park, Jae Chang [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Jeong, Yeon Seop; Chu, Gang Il [Korea Hydro and Nuclear Power, Daejeon (Korea, Republic of)

    2010-05-15

    The action verbs used in Emergency Operating Procedures (EOPs) for each nuclear power plant are translated respectively from the action verbs used in Emergency Recovery Guidelines (ERG) of the reference plants. The action verbs used in each plant are not largely different with one another. There are, however, some cases that the meanings of the same action verbs used in different plants are not consistent with each other and translations are not exact. In this study, the original English expressions of the action verbs and the translated verbs were compared and their accepted meanings analyzed. And then, standardization for the action verbs which are not exactly translated or which are used with different meanings among the plants was proposed

  3. Enhanced Oceanic Operations Human-In-The-Loop In-Trail Procedure Validation Simulation Study

    Science.gov (United States)

    Murdoch, Jennifer L.; Bussink, Frank J. L.; Chamberlain, James P.; Chartrand, Ryan C.; Palmer, Michael T.; Palmer, Susan O.

    2008-01-01

    The Enhanced Oceanic Operations Human-In-The-Loop In-Trail Procedure (ITP) Validation Simulation Study investigated the viability of an ITP designed to enable oceanic flight level changes that would not otherwise be possible. Twelve commercial airline pilots with current oceanic experience flew a series of simulated scenarios involving either standard or ITP flight level change maneuvers and provided subjective workload ratings, assessments of ITP validity and acceptability, and objective performance measures associated with the appropriate selection, request, and execution of ITP flight level change maneuvers. In the majority of scenarios, subject pilots correctly assessed the traffic situation, selected an appropriate response (i.e., either a standard flight level change request, an ITP request, or no request), and executed their selected flight level change procedure, if any, without error. Workload ratings for ITP maneuvers were acceptable and not substantially higher than for standard flight level change maneuvers, and, for the majority of scenarios and subject pilots, subjective acceptability ratings and comments for ITP were generally high and positive. Qualitatively, the ITP was found to be valid and acceptable. However, the error rates for ITP maneuvers were higher than for standard flight level changes, and these errors may have design implications for both the ITP and the study's prototype traffic display. These errors and their implications are discussed.

  4. Congenital penile curvature: long-term results of operative treatment using the plication procedure

    Institute of Scientific and Technical Information of China (English)

    S.-S.Lee; E.Meng; E-RChuang; C.-Y.Yen; S.-Y.Chang; D.-S.Yu; G.-H.Sun

    2004-01-01

    Aim: To determine the long-term outcome, effectiveness and patient satisfaction of congenital penile curvature correction by plication of tunica albuginea. Methods: From January 1992 to January 2002, 106 young patients underwent surgical correction of congenital penile curvature by corporeal plication. Indications for operation were difficult or impossible vaginal penetration and cosmetic problems. The technique of corporeal plication consists of placing longitudinal plication sutures of 2-zero braided polyester on the convex side of the curvature until the curvature is corrected when erection is artificially induced. Results of this procedure were obtained by retrospective chart reviews and questionnaires via mail. Long-term follow-up ranged from 11 to 132 (mean 69.3) months and data were available for 68 patients. Results: Penile straightening was excellent in 62 patients (91%) and good with less than 15 degree of residual curvature in 6 patients (9 %). Sixty-seven patients reported no change in erectile rigidity or maintenance postoperatively, while 1 described early detumescence. Shortening of the penis without functional problems was noted by 26 patients (38 %). Thirty-Five patients (51%) reported feeling palpable indurations (suture knots) on the penis. Temporary numbness of glans penis was described in 3 patients. Overall, 60 patients were very satisfied, 6 satisfied, 2 unsatisfied. Conclusion: Corporeal plication is an effective and durable procedure with a high rate of patient satisfaction. (Asian J Androl 2004 Sep; 6: 273-276)

  5. Congenital penile curvature: long-term results of operative treatment using the plication procedure.

    Science.gov (United States)

    Lee, S-S; Meng, E; Chuang, F-P; Yen, C-Y; Chang, S-Y; Yu, D-S; Sun, G-H

    2004-09-01

    To determine the long-term outcome, effectiveness and patient satisfaction of congenital penile curvature correction by plication of tunica albuginea. From January 1992 to January 2002, 106 young patients underwent surgical correction of congenital penile curvature by corporeal plication. Indications for operation were difficult or impossible vaginal penetration and cosmetic problems. The technique of corporeal plication consists of placing longitudinal plication sutures of 2-zero braided polyester on the convex side of the curvature until the curvature is corrected when erection is artificially induced. Results of this procedure were obtained by retrospective chart reviews and questionnaires via mail. Long-term follow-up ranged from 11 to 132 (mean 69.3) months and data were available for 68 patients. Penile straightening was excellent in 62 patients (91 %) and good with less than 15 degree of residual curvature in 6 patients (9 %). Sixty-seven patients reported no change in erectile rigidity or maintenance postoperatively, while 1 described early detumescence. Shortening of the penis without functional problems was noted by 26 patients (38 %). Thirty-Five patients (51 %) reported feeling palpable indurations (suture knots) on the penis. Temporary numbness of glans penis was described in 3 patients. Overall, 60 patients were very satisfied, 6 satisfied, 2 unsatisfied. Corporeal plication is an effective and durable procedure with a high rate of patient satisfaction.

  6. An operative gamma camera for sentinel lymph node procedure in case of breast cancer

    CERN Document Server

    Salvador, S; Mathelin, C; Guyonne, J; Huss, D

    2007-01-01

    Large field of view gamma cameras are widely used to perform lymphoscintigraphy in the sentinel lymph nodes (SLN) procedure in case of breast cancer. However, they are not specified for this application and their sizes do not enable their use in the operative room to control the excision of the all SLN. We present the results obtained with a prototype of a new mini gamma camera developed especially for the operative lymphoscintigraphy of the axillary area in case of breast cancer. This prototype is composed of 10 mm thick parallel lead collimator, a 2 mm thick GSO:Ce inorganic scintillating crystal from Hitachi and a Hamamatsu H8500 flat panel multianode (64 channels) photomultiplier tube (MAPMT) equipped with a dedicated electronics. Its actual field of view is 50 × 50mm2. The gamma interaction position in the GSO scintillating plate is obtained by calculating the center of gravity of the fired MAPMT channels. The measurements performed with this prototype demonstrate the usefulness of this mini gamma camer...

  7. HEMP emergency planning and operating procedures for electric power systems. Power Systems Technology Program

    Energy Technology Data Exchange (ETDEWEB)

    Reddoch, T.W.; Markel, L.C. [Electrotek Concepts, Inc., Knoxville, TN (United States)

    1991-12-31

    Investigations of the impact of high-altitude electromagnetic pulse (HEMP) on electric power systems and electrical equipment have revealed that HEMP creates both misoperation and failures. These events result from both the early time E{sub 1} (steep-front pulse) component and the late time E{sub 3} (geomagnetic perturbations) component of HEMP. In this report a HEMP event is viewed in terms of its marginal impact over classical power system disturbances by considering the unique properties and consequences of HEMP. This report focuses on system-wide electrical component failures and their potential consequences from HEMP. In particular, the effectiveness of planning and operating procedures for electric systems is evaluated while under the influence of HEMP. This assessment relies on published data and characterizes utilities using the North American Electric Reliability Council`s regions and guidelines to model electric power system planning and operations. Key issues addressed by the report include how electric power systems are affected by HEMP and what actions electric utilities can initiate to reduce the consequences of HEMP. The report also reviews the salient features of earlier HEMP studies and projects, examines technology trends in the electric power industry which are affected by HEMP, characterizes the vulnerability of power systems to HEMP, and explores the capability of electric systems to recover from a HEMP event.

  8. HEMP emergency planning and operating procedures for electric power systems. Power Systems Technology Program

    Energy Technology Data Exchange (ETDEWEB)

    Reddoch, T.W.; Markel, L.C. [Electrotek Concepts, Inc., Knoxville, TN (United States)

    1991-12-31

    Investigations of the impact of high-altitude electromagnetic pulse (HEMP) on electric power systems and electrical equipment have revealed that HEMP creates both misoperation and failures. These events result from both the early time E{sub 1} (steep-front pulse) component and the late time E{sub 3} (geomagnetic perturbations) component of HEMP. In this report a HEMP event is viewed in terms of its marginal impact over classical power system disturbances by considering the unique properties and consequences of HEMP. This report focuses on system-wide electrical component failures and their potential consequences from HEMP. In particular, the effectiveness of planning and operating procedures for electric systems is evaluated while under the influence of HEMP. This assessment relies on published data and characterizes utilities using the North American Electric Reliability Council`s regions and guidelines to model electric power system planning and operations. Key issues addressed by the report include how electric power systems are affected by HEMP and what actions electric utilities can initiate to reduce the consequences of HEMP. The report also reviews the salient features of earlier HEMP studies and projects, examines technology trends in the electric power industry which are affected by HEMP, characterizes the vulnerability of power systems to HEMP, and explores the capability of electric systems to recover from a HEMP event.

  9. A Guide for Developing Standard Operating Job Procedures for the Tertiary Multimedia Filtration Process Wastewater Treatment Facility. SOJP No. 7.

    Science.gov (United States)

    Petrasek, Al, Jr.

    This guide describes the standard operating job procedures for the tertiary multimedia filtration process of wastewater treatment plants. The major objective of the filtration process is the removal of suspended solids from the reclaimed wastewater. The guide gives step-by-step instructions for pre-start up, start-up, continuous operation, and…

  10. 30 CFR 761.15 - Procedures for waiving the prohibition on surface coal mining operations within the buffer zone...

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Procedures for waiving the prohibition on surface coal mining operations within the buffer zone of an occupied dwelling. 761.15 Section 761.15... surface coal mining operations within the buffer zone of an occupied dwelling. (a) This section does not...

  11. 19 CFR 122.173 - Application procedures.

    Science.gov (United States)

    2010-04-01

    ..., each application will be reviewed to determine whether the procedures contained therein meet the requirements of the ACSPP. In determining whether a SOP submitted by an applicant carrier contains sufficient...) Assure the carrier employs a system to assure that no unmanifested cargo is placed on board...

  12. Activation of Akt by the bacterial inositol phosphatase, SopB, is wortmannin insensitive.

    Directory of Open Access Journals (Sweden)

    Kendal G Cooper

    Full Text Available Salmonella enterica uses effector proteins translocated by a Type III Secretion System to invade epithelial cells. One of the invasion-associated effectors, SopB, is an inositol phosphatase that mediates sustained activation of the pro-survival kinase Akt in infected cells. Canonical activation of Akt involves membrane translocation and phosphorylation and is dependent on phosphatidyl inositide 3 kinase (PI3K. Here we have investigated these two distinct processes in Salmonella infected HeLa cells. Firstly, we found that SopB-dependent membrane translocation and phosphorylation of Akt are insensitive to the PI3K inhibitor wortmannin. Similarly, depletion of the PI3K regulatory subunits p85α and p85ß by RNAi had no inhibitory effect on SopB-dependent Akt phosphorylation. Nevertheless, SopB-dependent phosphorylation does depend on the Akt kinases, PDK1 and rictor-mTOR. Membrane translocation assays revealed a dependence on SopB for Akt recruitment to Salmonella ruffles and suggest that this is mediated by phosphoinositide (3,4 P(2 rather than phosphoinositide (3,4,5 P(3. Altogether these data demonstrate that Salmonella activates Akt via a wortmannin insensitive mechanism that is likely a class I PI3K-independent process that incorporates some essential elements of the canonical pathway.

  13. Intense convection over West Africa during AMMA SOP3 experiment

    Science.gov (United States)

    Lenouo, André; Sall, Saïdou Moustapha; Badiane, Daouda; Gaye, Amadou Thierno; Kamga Mkankam, F.

    2016-11-01

    ERA-Interim product from the European Center for Medium-Range Weather Forecast (ECMWF) assimilation of African Monsoon Multidisciplinary Analysis (AMMA) resources, Meteosat satellite images, and synoptic observations were used to study local- and regional-scale environments associated with intense convective systems during the AMMA-SOP3 experiment over West Africa in the Northern Hemisphere of summer 2006. The convective system, from the 21st to 23rd of August 2006, was more active at 0000 and 1800 UTC showing diurnal cycle of deep convection over West Africa where the African easterly waves (AEWs) are developed downstream. Downstream barotropic and baroclinic energy conversions associated with strong AEWs are important for the maintenance of AEW activity in West Africa. Barotropic energy conversions dominate south of the African easterly jet (AEJ), while baroclinic energy conversions are most important north of the AEJ. From a dynamical viewpoint, the low-level vorticity presents strong positive values over the sea and Sahara zone, indicating that exists on the cyclonic shear side of the African easterly jet, which is consistent with baroclinic growth. The 925-hPa equivalent potential temperature structure show a maximum over the Sahara which corresponds to the depression observed in this region. A mosaic of three hourly infrared (IR) satellite images, depicts a very distinct signal from an initial region of convection, developing through several stages and moving off the African coast. These observations, along with those available from the World Weather Watch, provide an opportunity to carry out numerical weather prediction (NWP) studies over West Africa utilizing high resolution limited area models.

  14. Haloarchaeal gas vesicle nanoparticles displaying Salmonella SopB antigen reduce bacterial burden when administered with live attenuated bacteria.

    Science.gov (United States)

    DasSarma, Priya; Negi, Vidya Devi; Balakrishnan, Arjun; Karan, Ram; Barnes, Susan; Ekulona, Folasade; Chakravortty, Dipshikha; DasSarma, Shiladitya

    2014-07-31

    Innovative vaccines against typhoid and other Salmonella diseases that are safe, effective, and inexpensive are urgently needed. In order to address this need, buoyant, self-adjuvating gas vesicle nanoparticles (GVNPs) from the halophilic archaeon Halobacterium sp. NRC-1 were bioengineered to display the highly conserved Salmonella enterica antigen SopB, a secreted inosine phosphate effector protein injected by pathogenic bacteria during infection into the host cell. Two highly conserved sopB gene segments near the 3'-coding region, named sopB4 and B5, were each fused to the gvpC gene, and resulting GVNPs were purified by centrifugally accelerated flotation. Display of SopB4 and B5 antigenic epitopes on GVNPs was established by Western blotting analysis using antisera raised against short synthetic peptides of SopB. Immunostimulatory activities of the SopB4 and B5 nanoparticles were tested by intraperitoneal administration of recombinant GVNPs to BALB/c mice which had been immunized with S. enterica serovar Typhimurium 14028 ΔpmrG-HM-D (DV-STM-07), a live attenuated vaccine strain. Proinflammatory cytokines IFN-γ, IL-2, and IL-9 were significantly induced in mice boosted with SopB5-GVNPs, consistent with a robust Th1 response. After challenge with virulent S. enterica serovar Typhimurium 14028, bacterial burden was found to be diminished in spleen of mice boosted with SopB4-GVNPs and absent or significantly diminished in liver, mesenteric lymph node, and spleen of mice boosted with SopB5-GVNPs, indicating that the C-terminal portions of SopB displayed on GVNPs elicit a protective response to Salmonella infection in mice. SopB antigen-GVNPs were found to be stable at elevated temperatures for extended periods without refrigeration in Halobacterium cells. The results all together show that bioengineered GVNPs are likely to represent a valuable platform for the development of improved vaccines against Salmonella diseases.

  15. Tableau-based decision procedure for the multi-agent epistemic logic with operators of common and distributed knowledge

    CERN Document Server

    Goranko, Valentin

    2008-01-01

    We develop an incremental-tableau-based decision procedure for the multi-agent epistemic logic MAEL(CD) (aka S5_n (CD)), whose language contains operators of individual knowledge for a finite set Ag of agents, as well as operators of distributed and common knowledge among all agents in Ag. Our tableau procedure works in (deterministic) exponential time, thus establishing an upper bound for MAEL(CD)-satisfiability that matches the (implicit) lower-bound known from earlier results, which implies ExpTime-completeness of MAEL(CD)-satisfiability. Therefore, our procedure provides a complexity-optimal algorithm for checking MAEL(CD)-satisfiability, which, however, in most cases is much more efficient. We prove soundness and completeness of the procedure, and illustrate it with an example.

  16. Solution Procedure for Transport Modeling in Effluent Recharge Based on Operator-Splitting Techniques

    Directory of Open Access Journals (Sweden)

    Shutang Zhu

    2008-01-01

    Full Text Available The coupling of groundwater movement and reactive transport during groundwater recharge with wastewater leads to a complicated mathematical model, involving terms to describe convection-dispersion, adsorption/desorption and/or biodegradation, and so forth. It has been found very difficult to solve such a coupled model either analytically or numerically. The present study adopts operator-splitting techniques to decompose the coupled model into two submodels with different intrinsic characteristics. By applying an upwind finite difference scheme to the finite volume integral of the convection flux term, an implicit solution procedure is derived to solve the convection-dominant equation. The dispersion term is discretized in a standard central-difference scheme while the dispersion-dominant equation is solved using either the preconditioned Jacobi conjugate gradient (PJCG method or Thomas method based on local-one-dimensional scheme. The solution method proposed in this study is applied to the demonstration project of groundwater recharge with secondary effluent at Gaobeidian sewage treatment plant (STP successfully.

  17. Decentralized operating procedures for orchestrating data and behavior across distributed military systems and assets

    Science.gov (United States)

    Peach, Nicholas

    2011-06-01

    In this paper, we present a method for a highly decentralized yet structured and flexible approach to achieve systems interoperability by orchestrating data and behavior across distributed military systems and assets with security considerations addressed from the beginning. We describe an architecture of a tool-based design of business processes called Decentralized Operating Procedures (DOP) and the deployment of DOPs onto run time nodes, supporting the parallel execution of each DOP at multiple implementation nodes (fixed locations, vehicles, sensors and soldiers) throughout a battlefield to achieve flexible and reliable interoperability. The described method allows the architecture to; a) provide fine grain control of the collection and delivery of data between systems; b) allow the definition of a DOP at a strategic (or doctrine) level by defining required system behavior through process syntax at an abstract level, agnostic of implementation details; c) deploy a DOP into heterogeneous environments by the nomination of actual system interfaces and roles at a tactical level; d) rapidly deploy new DOPs in support of new tactics and systems; e) support multiple instances of a DOP in support of multiple missions; f) dynamically add or remove run-time nodes from a specific DOP instance as missions requirements change; g) model the passage of, and business reasons for the transmission of each data message to a specific DOP instance to support accreditation; h) run on low powered computers with lightweight tactical messaging. This approach is designed to extend the capabilities of existing standards, such as the Generic Vehicle Architecture (GVA).

  18. Monitoring complex detectors: the uSOP approach in the Belle II experiment

    Science.gov (United States)

    Di Capua, F.; Aloisio, A.; Ameli, F.; Anastasio, A.; Branchini, P.; Giordano, R.; Izzo, V.; Tortone, G.

    2017-08-01

    uSOP is a general purpose single board computer designed for deep embedded applications in control and monitoring of detectors, sensors and complex laboratory equipments. It is based on the AM3358 (1 GHz ARM Cortex A8 processor), equipped with USB and Ethernet interfaces. On-board RAM and solid state storage allows hosting a full LINUX distribution. In this paper we discuss the main aspects of the hardware and software design and the expandable peripheral architecture built around field busses. We report on several applications of uSOP system in the Belle II experiment, presently under construction at KEK (Tsukuba, Japan). In particular we will report the deployment of uSOP in the monitoring system framework of the endcap electromagnetic calorimeter.

  19. 21 CFR 123.11 - Sanitation control procedures.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Sanitation control procedures. 123.11 Section 123...) FOOD FOR HUMAN CONSUMPTION FISH AND FISHERY PRODUCTS General Provisions § 123.11 Sanitation control procedures. (a) Sanitation SOP. Each processor should have and implement a written sanitation...

  20. The Caenorhabditis elegans PcG-like gene sop-2 regulates the temporal and sexual specificities of cell fates.

    Science.gov (United States)

    Cai, Qingchun; Sun, Yinyan; Huang, Xinxin; Guo, Cong; Zhang, Yuxia; Zhu, Zuoyan; Zhang, Hong

    2008-03-01

    How spatial, temporal, and sexual specific cues are integrated to specify distinct cell fates during multicellular organism development is largely unknown. Here we demonstrate that the Caenorhabditis elegans PcG-like gene sop-2 determines the temporal and sexual specificities of a row of hypodermal seam cells, in addition to specifying their positional identities. Loss-of-function of sop-2 causes premature expression of adult fates at larval stages. sop-2 acts upstream of lin-29 in the heterochronic pathway and genetically interacts with other heterochronic genes in specifying the temporal fates of seam cells at different larval stages. We show that the number of ALG-1-containing P bodies is increased in seam cells in sop-2 mutants. Furthermore, the microRNA-mediated repression of a heterochronic gene reporter is enhanced in sop-2 mutants. Mutations in sop-2 also cause partial hermaphrodite-to-male sexual transformations. The homeotic transformations, heterochronic defects, and sexual transformations can occur concomitantly in sop-2 mutants. In summary, our studies reveal that sop-2 integrates spatial, temporal, and sexual cues during C. elegans development.

  1. The virulence protein SopD2 regulates membrane dynamics of Salmonella-containing vacuoles.

    Directory of Open Access Journals (Sweden)

    Nina Schroeder

    Full Text Available Salmonella enterica serovar Typhimurium is a Gram-negative bacterial pathogen causing gastroenteritis in humans and a systemic typhoid-like illness in mice. The capacity of Salmonella to cause diseases relies on the establishment of its intracellular replication niche, a membrane-bound compartment named the Salmonella-containing vacuole (SCV. This requires the translocation of bacterial effector proteins into the host cell by type three secretion systems. Among these effectors, SifA is required for the SCV stability, the formation of Salmonella-induced filaments (SIFs and plays an important role in the virulence of Salmonella. Here we show that the effector SopD2 is responsible for the SCV instability that triggers the cytoplasmic release of a sifA(- mutant. Deletion of sopD2 also rescued intra-macrophagic replication and increased virulence of sifA(- mutants in mice. Membrane tubular structures that extend from the SCV are the hallmark of Salmonella-infected cells. Until now, these unique structures have not been observed in the absence of SifA. The deletion of sopD2 in a sifA(- mutant strain re-established membrane trafficking from the SCV and led to the formation of new membrane tubular structures, the formation of which is dependent on other Salmonella effector(s. Taken together, our data demonstrate that SopD2 inhibits the vesicular transport and the formation of tubules that extend outward from the SCV and thereby contributes to the sifA(- associated phenotypes. These results also highlight the antagonistic roles played by SopD2 and SifA in the membrane dynamics of the vacuole, and the complex actions of SopD2, SifA, PipB2 and other unidentified effector(s in the biogenesis and maintenance of the Salmonella replicative niche.

  2. Impact of North Atlantic Treaty Organization Policies and Procedures on Combined Medical Operations: Food and Water Safety and Veterinary Support.

    Science.gov (United States)

    Stevenson, Timothy H; Chevalier, Nicole A; Scher, Gregory R; Burke, Ronald L

    2016-01-01

    Effective multilateral military operations such as those conducted by the North Atlantic Treaty Organization (NATO) require close cooperation and standardization between member nations to ensure interoperability. Failure to standardize policies, procedures, and doctrine prior to the commencement of military operations will result in critical interoperability gaps, which jeopardize the health of NATO forces and mission success. To prevent these gaps from occurring, US forces must be actively involved with NATO standardization efforts such as the Committee of the Chiefs of Medical Services to ensure US interests are properly represented when NATO standards are developed and US doctrine and procedures will meet the established NATO requirements.

  3. Influence of SOP modes on Raman spectra of ZnO(Fe) nanoparticles

    Science.gov (United States)

    Hadžić, B.; Romčević, N.; Romčević, M.; Kuryliszyn-Kudelska, I.; Dobrowolski, W.; Narkiewicz, U.; Sibera, D.

    2015-04-01

    Nanocrystaline samples of ZnO(Fe) were synthesized by traditional wet chemical method followed by calcinations. Samples were characterized by X-ray diffraction to determine composition of the samples (ZnO, ZnFe2O4 and Fe2O3) and the mean crystalline size (from 8 to 51 nm). In this paper we report the experimental spectra of Raman scattering (from 200 to 1600 cm-1) with surface optical phonons (SOP) in range of 500-550 cm-1. The phonon of registered phase's exhibit effects connected to phase concentration, while the SOP phonon mode exhibit significant confinement effect.

  4. The effect of bending and twisting on the stiffness and strength of the 3.5 SOP implant.

    Science.gov (United States)

    Ness, M G

    2009-01-01

    Locking plates are becoming increasingly popular in veterinary orthopaedics. The SOP is a novel locking plate system, which can be contoured with 6 degrees of freedom and which utilises standard bone screws. The purpose of this work was to investigate the mechanical consequences of contouring the 3.5 SOP plate to support the formulation of clinical guidelines. The implants were loaded in four point bending using an industry standard protocol. The uncontoured SOP was found to be significantly stiffer and stronger than the uncontoured 3.5 DCP. Bending, and to a lesser extent, twisting, diminished the SOP's stiffness and strength but the contoured SOP remained at least as stiff and strong as the untouched DCP.

  5. The current status of procedural sedation for pediatric patients in out-of-operating room locations.

    Science.gov (United States)

    Havidich, Jeana E; Cravero, Joseph P

    2012-08-01

    To illustrate the changes that are occurring in the rapidly growing field of pediatric sedation. In the USA and throughout the world, children receive sedation from a multitude of specialists with varying levels of training. The current pediatric sedation literature reflects a growing body of sedation literature by medical specialists other than anesthesiologists. This article will review the controversial use of propofol by nonanesthesiologists and the manner in which this varied group of providers along with government entities, regulatory agencies, and national organizations contribute to the continuing evolution of sedation practices. The number of diagnostic and therapeutic procedures performed on children outside of the operating room continues to increase. The growing body of pediatric sedation literature suggests anesthesiologists are no longer at the forefront of pediatric sedation training, education, and research. Articles published by nonanesthesiologists describe pediatric sedation services, safety, and quality initiatives, drugs, and original sedation research. Medications that were considered under the realm of anesthesiologists are utilized by nonanesthesiologists to provide sedation to children. Regulating and government agencies, including the Joint Commission and the Center for Medicaid and Medicare Services have recently issued statements on the oversight and practice of sedation. The direction of pediatric sedation is no longer solely under the leadership of anesthesiologists. The use of anesthetic agents, including propofol, have been administered by nonanesthesiologists and reported as safe and effective agents. Nonanesthesiologists and governmental and regulatory agencies influence the delivery of sedation services. The future direction of pediatric sedation will ultimately depend upon the ability of anesthesiologists to collaborate with specialists, hospital administrators, credentialing committees, and oversight agencies in order to

  6. EVALUATION OF INJ. CLONIDINE IN MAINTAINING HAEMODYNAMICS DURING LAPAROSCOPIC OPERATIVE PROCEDURES

    Directory of Open Access Journals (Sweden)

    Todkari Kiran

    2016-05-01

    Full Text Available Pneumoperitoneum usually with CO2 insufflations created during laparoscopic operative procedures affects several homeostatic systems leading to adverse effects on cardiovascular and pulmonary physiology and produces stress response. There is increase in pulse rate, systolic blood pressure and decrease in cardiac output and increase in systemic vascular resistance. Clonidine an α2 agonist with its central sympatholytic action attenuates the cardiovascular adverse effects and provide intraoperative as well as postoperative analgesia. In the present study, 60 ASA grade I and II of either sex between age range of 18–60 years and weight range of 45–70 kg were divided into 2 equal groups of 30 each. Group A served as control group A, received inj. Midazolam 0.03 mg/kg and inj. Pentazocine 0.3 mg/kg as premedication 15 minutes prior to induction of anaesthesia and group B received inj. Clonidine 1 µgm/kg as premedication before induction of anaesthesia. Anaesthesia was induced with inj. Thiopentone 5 mg/kg and inj. Vecuronium 0.1 mg/kg in all patients. All patients were maintained on oxygen, nitrous oxide and inj. Propofol infusion on IPPV. Pneumoperitoneum was created with CO2 and intra-abdominal pressure was maintained on 15 mmHg. All patients were observed for changes in pulse rate, systolic blood pressure, EtCO2 throughout intraoperative period. Normocapnia was maintained. It was observed that Clonidine group provided statistically significant cardiovascular stability with less increase in pulse rate and systolic blood pressure. The requirement of additional analgesic drugs was minimum in Clonidine group with minimal sedation. Thus, it was concluded that premedication with inj. Clonidine in dose of 1 µgm/kg prior to induction of anaesthesia provides effective cardiovascular stability and attenuates the increase in pulse rate, systolic blood pressure, decrease in cardiac output and increase in systemic vascular resistance secondary to

  7. Prediction of post-operative pain after a laparoscopic tubal ligation procedure

    DEFF Research Database (Denmark)

    Rudin, A.; Wolner-Hanssen, P.; Hellbom, M.

    2008-01-01

    BACKGROUND: Pre-operative identification of reliable predictors of post-operative pain may lead to improved pain management strategies. We investigated the correlation between pre-operative pain, psychometric variables, response to heat stimuli and post-operative pain following a laparoscopic tub...

  8. [Importance of displacement ventilation for operations and small surgical procedures from the infection preventive point of view].

    Science.gov (United States)

    Kramer, A; Külpmann, R; Wille, F; Christiansen, B; Exner, M; Kohlmann, T; Heidecke, C D; Lippert, H; Oldhafer, K; Schilling, M; Below, H; Harnoss, J C; Assadian, O

    2010-02-01

    Surgical teams need to breathe air that is conducive to their health. An adequate exchange of air ensures oxygen supply, the ventilation of humidity, smells, toxic substances, especially narcotic gases and surgical smoke, pathogens and particles. With regard to the infection risk, DIN 1946 / 4 -differentiates between operation theaters with the highest demand for clean air (operation room class I a), operation theatres with a high demand (operation room class I b) and rooms within the operation theatres without special requirements, meaning that the microbial load in the air is close to or equal to that of normal in-room air quality (room class II). For an operation room class I a, ventilation that displaces the used air is necessary, while a regular ventilation is sufficient for operation room class I b. Because of ambiguous -results in previous studies, the necessity to define a -class I a for operation rooms is being questioned. Therefore, this review focuses on the analysis of the existing publications with respect to this -question. The result of this analysis indicates that so far there is only one surgical procedure, the -implantation of hip endoprosthetics, for which a preventive effect on SSI of a class I a ventilation (displacement of the used air) is documented. One recent study, reviewed critically here, -showed opposite results, but lacks methodological clarity. Thus, it is concluded that evidence for the requirement of operation room classes can only be derived from risk assessment (infection risk by surgical intervention, extent of possible damages), but not from epidemiological studies. Risk assessment must be based on the following criteria: size and depth of the operation field, -duration of the procedure, vascular perfusion of the wound, implantation of alloplastic material and general risk of the patient for an infection. From an infection preventive point of view, no class I a "displacement ventilation" is necessary for small surgical

  9. Factors Surgical Team Members Perceive Influence Choices of Wearing or Not Wearing Personal Protective Equipment during Operative/Invasive Procedures

    Science.gov (United States)

    Cuming, Richard G.

    2009-01-01

    Exposure to certain bloodborne pathogens can prematurely end a person's life. Healthcare workers (HCWs), especially those who are members of surgical teams, are at increased risk of exposure to these pathogens. The proper use of personal protective equipment (PPE) during operative/invasive procedures reduces that risk. Despite this, some HCWs fail…

  10. Tableau-based decision procedure for the multiagent epistemic logic with all coalitional operators for common and distributed knowledge

    DEFF Research Database (Denmark)

    Ajspur, Mai; Goranko, Valentin; Shkatov, Dmitry

    2013-01-01

    We develop a conceptually clear, intuitive and feasible decision procedure for testing satisfiability in the full multiagent epistemic logic CMAEL(CD) with operators for common and distributed knowledge for all coalitions of agents mentioned in the language. To that end, we introduce Hintikka str...

  11. Factors Surgical Team Members Perceive Influence Choices of Wearing or Not Wearing Personal Protective Equipment during Operative/Invasive Procedures

    Science.gov (United States)

    Cuming, Richard G.

    2009-01-01

    Exposure to certain bloodborne pathogens can prematurely end a person's life. Healthcare workers (HCWs), especially those who are members of surgical teams, are at increased risk of exposure to these pathogens. The proper use of personal protective equipment (PPE) during operative/invasive procedures reduces that risk. Despite this, some HCWs fail…

  12. Plastic surgery within the Veterans Affairs Medical System: proposed modified indications for operative procedures.

    Science.gov (United States)

    Erdmann, Detlev; Pradka, Sarah P; Similie, Ernest; Marcus, Jeffrey R; Moyer, Kurtis E; Shelburne, John D; Tyler, Douglas S; Levin, Scott L

    2009-07-01

    Many plastic surgery procedures span the divide between aesthetic ("cosmetic") and reconstructive surgery. However, definitions and guidelines may be inconsistent, which may decrease patients' access to legitimate procedures. The article aims to assist Veterans' Health Administration-affiliated plastic surgeons in continuing to provide optimal care to the Nation's Veterans and family members, and should be regarded as an open discussion.

  13. Impact of operator fatigue on endoscopy performance: implications for procedure scheduling.

    LENUS (Irish Health Repository)

    Harewood, Gavin C

    2009-08-01

    With increasing volumes of endoscopic procedures, endoscopists\\' workload has had to increase to meet this escalating demand. The aim of this study was to characterize the impact of endoscopist fatigue on quality of endoscopy performance by comparing outcomes based on chronological procedure order.

  14. Build up An Operational Flood Simulation from Existing 1D Channel Flow Works

    Science.gov (United States)

    Chang, Che-Hao; Hsu, Chih-Tsung; Wu, Shiang-Jen; Lien, Ho-Cheng; Shen, Jhih-Cyuan; Chung, Ming-Ko

    2016-04-01

    Several 2D flood simulations will be developed for urban area in recent years in Taiwan. Original ideas focus on the static flood maps produced by the 2D flood simulation with respect to design events, which could be useful no matter for planning or disaster awareness. However, an extra bonus is expected to see if we can reuse the 2D flood simulation framework for operational use or not. Such a project goal inspire us to setup a standard operation procedure before any progress from existing 1D channel flow works. 3 key issues are taken into account in the SOP: 1. High Resolution Terrain: A 1m resolution digital terrain model (DTM) is considered as a reference. The Channels and structures should be setup in 1D channel flow works if we can identify under such high resolution. One should examine the existing 1D channel flow works consistent with the DTM or not. 2. Meteo Stations Referenced: Real time precipitation would be send to referenced location in RR models during an operational forecast. Existing 1D channels flow works are usually specifically for design events which are not necessarily equipped with such references. 3. Time Consuming: A full scale 2D flood simulation needs a lot of computation resources. A solution should be derived within practical time limits. Under the above consideration, some impacts and procedures will be analyzed and developed to setup the SOP for further model modification.

  15. Procedures for using expert judgment to estimate human-error probabilities in nuclear power plant operations. [PWR; BWR

    Energy Technology Data Exchange (ETDEWEB)

    Seaver, D.A.; Stillwell, W.G.

    1983-03-01

    This report describes and evaluates several procedures for using expert judgment to estimate human-error probabilities (HEPs) in nuclear power plant operations. These HEPs are currently needed for several purposes, particularly for probabilistic risk assessments. Data do not exist for estimating these HEPs, so expert judgment can provide these estimates in a timely manner. Five judgmental procedures are described here: paired comparisons, ranking and rating, direct numerical estimation, indirect numerical estimation and multiattribute utility measurement. These procedures are evaluated in terms of several criteria: quality of judgments, difficulty of data collection, empirical support, acceptability, theoretical justification, and data processing. Situational constraints such as the number of experts available, the number of HEPs to be estimated, the time available, the location of the experts, and the resources available are discussed in regard to their implications for selecting a procedure for use.

  16. SURF: Taking Sustainable Remediation from Concept to Standard Operating Procedure (Invited)

    Science.gov (United States)

    Smith, L. M.; Wice, R. B.; Torrens, J.

    2013-12-01

    Over the last decade, many sectors of industrialized society have been rethinking behavior and re-engineering practices to reduce consumption of energy and natural resources. During this time, green and sustainable remediation (GSR) has evolved from conceptual discussions to standard operating procedure for many environmental remediation practitioners. Government agencies and private sector entities have incorporated GSR metrics into their performance criteria and contracting documents. One of the early think tanks for the development of GSR was the Sustainable Remediation Forum (SURF). SURF brings together representatives of government, industry, consultancy, and academia to parse the means and ends of incorporating societal and economic considerations into environmental cleanup projects. Faced with decades-old treatment programs with high energy outputs and no endpoints in sight, a small group of individuals published the institutional knowledge gathered in two years of ad hoc meetings into a 2009 White Paper on sustainable remediation drivers, practices, objectives, and case studies. Since then, SURF has expanded on those introductory topics, publishing its Framework for Integrating Sustainability into Remediation Projects, Guidance for Performing Footprint Analyses and Life-Cycle Assessments for the Remediation Industry, a compendium of metrics, and a call to improve the integration of land remediation and reuse. SURF's research and members have also been instrumental in the development of additional guidance through ASTM International and the Interstate Technology and Regulatory Council. SURF's current efforts focus on water reuse, the international perspective on GSR (continuing the conversations that were the basis of SURF's December 2012 meeting at the National Academy of Sciences in Washington, DC), and ways to capture and evaluate the societal benefits of site remediation. SURF also promotes and supports student chapters at universities across the US

  17. Two simple multivariate procedures for monitoring planetary gearboxes in non-stationary operating conditions

    Science.gov (United States)

    Zimroz, Radoslaw; Bartkowiak, Anna

    2013-07-01

    This paper deals with the diagnostics of planetary gearboxes under nonstationary operating conditions. In most diagnostics applications, energy of vibration signals (calculated directly from time series or extracted from spectral representation of signal) is used. Unfortunately energy based features are sensitive to load conditions and it makes diagnostics difficult. In this paper we used energy based 15D data vectors (namely spectral amplitudes of planetary mesh frequency and its harmonics) in order to investigate if it is possible to improve diagnostics efficiency in comparison to previous, one dimensional, approaches proposed for the same problem. Two multivariate methods, Principal Component Analysis (PCA) and Canonical Discriminant Analysis (CDA), were used as techniques for data analysis. We used these techniques in order to investigate dimensionality of the data and to visualize data in 3D and 2D spaces in order to understand data behavior and assess classification ability. As a case study the data from two planetary gearboxes used in complex mining machines (one in bad condition and the other in good condition) were analyzed. For these two machines more than 2000 15D vectors were acquired. It should be noted that due to non-stationarity of loading conditions, previous diagnostics results obtained using other techniques were moderately good (ca. 80% recognition efficiency); however there is still some need to improve diagnostics classification ability. After application of the proposed approaches it was found that the entire data could be reduced to 2 dimensions whereby data instances became visible and a good discriminant function (characterized by a misclassification rate of .0023, i.e. only 5 erroneous classifications for a total of 2183 instances) could be derived. This paper suggests a novel way for condition monitoring of planetary gearboxes based on multivariate statistics. The emphasis is put on the algebraic and geometric interpretations of the PCA

  18. A Procedure for Building Product Models in Intelligent Agent-based OperationsManagement

    DEFF Research Database (Denmark)

    Hvam, Lars; Riis, Jesper; Malis, Martin;

    2003-01-01

    by product models. The next phase includes an analysis of the product assortment, and the set up of a so-called product master. Finally the product model is designed and implemented by using object oriented modelling. The procedure is developed in order to ensure that the product models constructed are fit......This article presents a procedure for building product models to support the specification processes dealing with sales, design of product variants and production preparation. The procedure includes, as the first phase, an analysis and redesign of the business processes that are to be supported...

  19. Stimulus representation in SOP: II. An application to inhibition of delay.

    Science.gov (United States)

    Vogel, Edgar H.; Brandon, Susan E.; Wagner, Allan R.

    2003-04-28

    The componential extension of SOP accounts for conditioned response (CR) timing in Pavlovian conditioning by assuming that learning accrues with relative independence to stimulus elements that are differentially occasioned during the duration of the conditioned stimulus (CS). SOP, using a competitive learning rule and the assumption that temporal learning emerges via resolution of what is equivalent to an "AX+BX-" discrimination, predicts a progressive increase in the latency of the CR over training, or what Pavlov refer to as "inhibition of delay." Other componential models, which use noncompetitive learning rules, do not predict inhibition of delay. Either type of model makes the prediction indicated, independently of the length of the CS-unconditioned stimulus (US) interval. We report two experiments that demonstrated inhibition of delay when rabbits were trained with relatively long, but not with short, CS-US intervals. To account for this divergence, we assumed that the SOP stimulus trace involves two kinds of elements, some with a temporally distributed pattern of activity over the duration of the CS duration, and some with a randomly distributed pattern. This stimulus representation, not only allows for inhibition of delay with long but not short CS-US intervals, but in combination with SOP's performance rule deduces CR's with "Weber variability."

  20. US EPA Base Study Standard Operating Procedure for Continuous Monitoring of Outdoor Air

    Science.gov (United States)

    The procedure described is intended for monitoring continuously and simultaneously outdoor air quality parameters that are most commonly associated with indoor air quality: the concentrations of carbon dioxide (CO2) and carbon monoxide (CO), temperature, nd relative humidity (RH).

  1. The price of surgery: markup of operative procedures in the United States.

    Science.gov (United States)

    Gani, Faiz; Makary, Martin A; Pawlik, Timothy M

    2017-02-01

    Despite cost containment efforts, the price for surgery is not subject to any regulations. We sought to characterize and compare variability in pricing for commonly performed major surgical procedures across the United States. Medicare claims corresponding to eight major surgical procedures (aortic aneurysm repair, aortic valvuloplasty, carotid endartectomy, coronary artery bypass grafting, esophagectomy, pancreatectomy, liver resection, and colectomy) were identified using the Medicare Provider Utilization and Payment Data Physician and Other Supplier Public Use File for 2013. For each procedure, total charges, Medicare-allowable costs, and total payments were recorded. A procedure-specific markup ratio (MR; ratio of total charges to Medicare-allowable costs) was calculated and compared between procedures and across states. Variation in MR was compared using a coefficient of variation (CoV). Among all providers, the median MR was 3.5 (interquartile range: 3.1-4.0). MR was noted to vary by procedure; ranging from 3.0 following colectomy to 6.0 following carotid endartectomy (P < 0.001). MR also varied for the same procedure; varying the least after liver resection (CoV = 0.24), while coronary artery bypass grafting pricing demonstrated the greatest variation in MR (CoV = 0.53). Compared with the national average, MR varied by 36% between states ranging from 1.8 to 13.0. Variation in MR was also noted within the same state varying by 15% within the state of Arkansas (CoV = 0.15) compared with 51% within the state of Wisconsin (CoV = 0.51). Significant variation was noted for the price of surgery by procedure as well as between and within different geographical regions. Greater scrutiny and transparency in the price of surgery is required to promote cost containment. Copyright © 2016 Elsevier Inc. All rights reserved.

  2. Test Operations Procedure (TOP) 01-1-065 Accelerated Corrosion Durability

    Science.gov (United States)

    2013-10-15

    as a general guide. This procedure is focused on metallic corrosion and does not accelerate Microbial Induced Corrosion (MIC) or degradation of non...metallic materials such as plastics or rubbers due to solar exposure or other causes of degradation besides what is identified in this procedure... concentration salt solutions that are present on roadways, typically from road deicing salts. The application includes exposure to fine mists from elevated

  3. Operational requirements for electronic chart display and information systems (ECDIS. Procedural and organizational considerations

    Directory of Open Access Journals (Sweden)

    Adam WEINTRIT

    2008-01-01

    Full Text Available Navigating with ECDIS is fundamentally different from navigating withpaper charts. The paper below lists a range of bridge work-processes that are affected by changing to an ECDIS system, and which may require that procedures are amended or developed. The paper includes some points for analysis and consideration. It is not implied that all items mentioned should result in corresponding written procedures, nor isit implied that the list in any way is conclusive.

  4. Dam methylation regulates the expression of SPI-5-encoded sopB gene in Salmonella enterica serovar Typhimurium.

    Science.gov (United States)

    Giacomodonato, Mónica N; Llana, Mariángeles Noto; Castañeda, María del Rosario Aya; Buzzola, Fernanda; García, Mauro D; Calderón, Marina Gallo; Sarnacki, Sebastián H; Cerquetti, María C

    2014-08-01

    DNA adenine methylation is an essential factor in Salmonella virulence. Here, we investigate the involvement of DNA adenine methylase (Dam) in the expression and translocation of a SPI-5-encoded effector of S. Typhimurium. SopB expression and secretion were determined using SopB-FLAG-tagged wild type and dam strains of S. Typhimurium. Western blot and quantitative reverse transcriptase PCR analysis showed that the dam mutant expresses lower levels of SopB protein and sopB mRNA than the wild type strain under SPI-1 and SPI-2 inducing conditions in vitro. SopB secretion was also considerably impaired in the absence of dam. In agreement with in vitro experiments, SopB synthesis in dam mutants recovered from infected epithelial cells and from murine mesenteric lymph nodes was reduced by 40% respect to the wild type strain (p dam mutant. Taken together, our results demonstrate that, in S. Typhimurium, Dam methylation modulates the expression and translocation of SPI-5-encoded SopB effector.

  5. [Error prevention through management of complications in urology: standard operating procedures from commercial aviation as a model].

    Science.gov (United States)

    Kranz, J; Sommer, K-J; Steffens, J

    2014-05-01

    Patient safety and risk/complication management rank among the current megatrends in modern medicine, which has undoubtedly become more complex. In time-critical, error-prone and difficult situations, which often occur repeatedly in everyday clinical practice, guidelines are inappropriate for acting rapidly and intelligently. With the establishment and consistent use of standard operating procedures like in commercial aviation, a possible strategic approach is available. These medical aids to decision-making - quick reference cards - are short, optimized instructions that enable a standardized procedure in case of medical claims.

  6. Requirements for Computer Based-Procedures for Nuclear Power Plant Field Operators Results from a Qualitative Study

    Energy Technology Data Exchange (ETDEWEB)

    Katya Le Blanc; Johanna Oxstrand

    2012-05-01

    Although computer-based procedures (CBPs) have been investigated as a way to enhance operator performance on procedural tasks in the nuclear industry for almost thirty years, they are not currently widely deployed at United States utilities. One of the barriers to the wide scale deployment of CBPs is the lack of operational experience with CBPs that could serve as a sound basis for justifying the use of CBPs for nuclear utilities. Utilities are hesitant to adopt CBPs because of concern over potential costs of implementation, and concern over regulatory approval. Regulators require a sound technical basis for the use of any procedure at the utilities; without operating experience to support the use CBPs, it is difficult to establish such a technical basis. In an effort to begin the process of developing a technical basis for CBPs, researchers at Idaho National Laboratory are partnering with industry to explore CBPs with the objective of defining requirements for CBPs and developing an industry-wide vision and path forward for the use of CBPs. This paper describes the results from a qualitative study aimed at defining requirements for CBPs to be used by field operators and maintenance technicians.

  7. Second Line of Defense Megaports Initiative Operational Testing and Evaluation Plan Colon Container Terminal (CCT) Panama

    Energy Technology Data Exchange (ETDEWEB)

    Newhouse, Robert N.

    2010-01-01

    Report on the Operational Testing and Evaluation to validate and baseline an operable system that meets the Second Line of Defense (SLD) mission requirements. An SLD system is defined as the detection technology and associated equipment, the system operators from the host country, the standard operating procedures (SOPs), and other elements such as training and maintenance which support long-term system sustainment. To this end, the activities conducted during the OT&E phase must demonstrate that the Megaports System can be operated effectively in real-time by Panama Direccion General de Aduanas (DGA Panama Customs) personnel to the standards of the U.S. Department of Energy/National Nuclear Security Administration (DOE/NNSA).

  8. Crohn′s disease: Multimodality Imaging of Surgical Indications, Operative Procedures, and Complications

    Directory of Open Access Journals (Sweden)

    B Kolar

    2011-01-01

    Full Text Available Surgical management is considered for specific indications in Crohn′s disease and a wide variety of surgeries is performed. The purpose of this pictorial essay is to depict manifestations of Crohn′s disease that indicates surgery, various surgical procedures that are performed, and the complications arising from these surgical procedures. Surgical indications including obstruction due to strictures or adhesions, fistulae and abscesses, and surgeries for these conditions, such as, ileocecectomy, stricturoplasty, small bowel resection, fecal diversion, segmental colectomy, and lysis of adhesions and their complications will be discussed and their imaging will also be illustrated.

  9. 33 CFR 157.226 - Dedicated Clean Ballast Tanks Operations Manual: Procedures to be followed.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Dedicated Clean Ballast Tanks... ENVIRONMENT RELATING TO TANK VESSELS CARRYING OIL IN BULK Dedicated Clean Ballast Tanks on Tank Vessels Dedicated Clean Ballast Tanks Operations § 157.226 Dedicated Clean Ballast Tanks Operations...

  10. 14 CFR Appendix I to Part 417 - Methodologies for Toxic Release Hazard Analysis and Operational Procedures

    Science.gov (United States)

    2010-01-01

    ... fully loaded propellant storage tanks or pressurized motor segments. (vii) Worst case combustion or... of each accident experienced by the launch operator involving the release of a toxic propellant; and..., including the launch operator's ground safety plan, hazard area surveillance and clearance plan,...

  11. Computerized operating procedures for shearing and dissolution of segments from LWBR (Light Water Breeder Reactor) fuel rods

    Energy Technology Data Exchange (ETDEWEB)

    Osudar, J.; Deeken, P.G.; Graczyk, D.G.; Fagan, J.E.; Martino, F.J.; Parks, J.E.; Levitz, N.M.; Kessie, R.W.; Leddin, J.M.

    1987-05-01

    This report presents two detailed computerized operating procedures developed to assist and control the shearing and dissolution of irradiated fuel rods. The procedures were employed in the destructive analysis of end-of-life fuel rods from the Light Water Breeder Reactor (LWBR) that was designed by the Westinghouse Electric Corporation Bettis Atomic Power Laboratory. Seventeen entire fuel rods from the end-of-life core of the LWBR were sheared into 169 precisely characterized segments, and more than 150 of these segments were dissolved during execution of the LWBR Proof-of-Breeding (LWBR-POB) Analytical Support Project at Argonne National Laboratory. The procedures illustrate our approaches to process monitoring, data reduction, and quality assurance during the LWBR-POB work.

  12. Impact of Technique-Specific Operative Videos on First-Year Dental Students' Performance of Restorative Procedures.

    Science.gov (United States)

    Patel, Shalizeh A; Barros, Juliana A; Clark, Christina M; Frey, Gary N; Streckfus, Charles F; Quock, Ryan L

    2015-09-01

    The aim of this study was to examine the impact of psychomotor operative video demonstrations on first-year dental students who are performing specific procedures for the first time in a preclinical setting. The class was randomly divided into two groups, and three restorative procedures were selected. On the date on which each procedure was to be performed in the preclinical laboratory for the first time, one group (experimental, n=50) was shown a technique video for that specific procedure immediately before commencing the exercise; the control cohort (n=50) did not view the video. Technical performance on procedures was evaluated by students and two calibrated and blinded examiners. The students' perceptions of the experience were also collected in a survey. All first-year students participated in the study, for a 100% response rate. A Mann-Whitney U test did not show any group differences in technical performance (mean values on preparation: 77.1 vs. 77.8; amalgam: 82.7 vs. 82.8; composite: 79.7 vs. 78.0). A Spearman rho test revealed a significantly higher correlation in 13 out of 25 evaluation categories between student self-assessment and blinded examiner assessment for the experimental group. A chi-square test of questionnaire responses revealed a positive student perception of administering these videos for the preparation (X(2)=4.8, pstudent performance on preclinical operative procedures, but they were well received by students and augmented self-assessment ability. These findings suggest that videos can be a useful teaching aid in a preclinical environment, especially regarding comprehension of concepts.

  13. Intercultural Education Set Forward: Operational Strategies and Procedures in Cypriot Classrooms

    Science.gov (United States)

    Hajisoteriou, Christina

    2012-01-01

    Teachers in Cyprus are being called upon for the first time to teach within culturally diverse educational settings. Given the substantial role, teachers play in the implementation of intercultural education, this paper explores the intercultural strategies and procedures adopted by primary school teachers in Cyprus. Interviews were carried out…

  14. Riding Standards. The Policies and Operating Procedures of the National Riding Committee 1973-74.

    Science.gov (United States)

    Cronin, Paul D., Ed.

    This booklet details the policies and rating procedures of the National Riding Committee. Chapters are devoted to the rating of riders with oral and written tests, the appointment of judges, types of certificates issued, rated rider examination requirements (forward riding section and western section), job placement, and advertising policy and…

  15. Strategy over operation: neural activation in subtraction and multiplication during fact retrieval and procedural strategy use in children.

    Science.gov (United States)

    Polspoel, Brecht; Peters, Lien; Vandermosten, Maaike; De Smedt, Bert

    2017-09-01

    Arithmetic development is characterized by strategy shifts between procedural strategy use and fact retrieval. This study is the first to explicitly investigate children's neural activation associated with the use of these different strategies. Participants were 26 typically developing 4th graders (9- to 10-year-olds), who, in a behavioral session, were asked to verbally report on a trial-by-trial basis how they had solved 100 subtraction and multiplication items. These items were subsequently presented during functional magnetic resonance imaging. An event-related design allowed us to analyze the brain responses during retrieval and procedural trials, based on the children's verbal reports. During procedural strategy use, and more specifically for the decomposition of operands strategy, activation increases were observed in the inferior and superior parietal lobes (intraparietal sulci), inferior to superior frontal gyri, bilateral areas in the occipital lobe, and insular cortex. For retrieval, in comparison to procedural strategy use, we observed increased activity in the bilateral angular and supramarginal gyri, left middle to inferior temporal gyrus, right superior temporal gyrus, and superior medial frontal gyrus. No neural differences were found between the two operations under study. These results are the first in children to provide direct evidence for alternate neural activation when different arithmetic strategies are used and further unravel that previously found effects of operation on brain activity reflect differences in arithmetic strategy use. Hum Brain Mapp 38:4657-4670, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  16. [Clinical relevance of unloading in cartilage therapy of the knee--shoe insoles, knee braces or additional operative procedure?].

    Science.gov (United States)

    Kraus, T M; Imhoff, A B; Ateschrang, A; Stöckle, U; Schröter, S

    2015-02-01

    Restoration of a neutral biomechanical environment and reduction of overload is an important factor contributing to the success of any cartilage repair procedure. Reduction of overload can by achieved by so called unloading procedures in order to reduce intraarticular pressure from the repair zone. Unloading can be achieved via loss of weight, wedged shoe insoles, knee braces or via operations such as osteotomies around the knee joint. The cartilage therapy and the concomitant unloading procedure should be adapted to the individual pathology and realistic aims of the patient. Wedged insoles and braces are the least invasive treatment methods. In comparison, however, beneficial effects of braces outline those of laterally wedged heels. Nevertheless long-term compliance with insoles and braces is poor. Concerning braces either because the positive effects of the braces are too small or because the adverse effects are too large. Unloading in the long run may only be achieved through operative procedures. When an osteotomy seems to be too invasive the arthroscopic release of the posterior oblique ligament might be an option. Patients with an intact contralateral chondral status, medium to slight malalignment who want to remain at high activity levels, remain good candidates for unloading osteotomies.

  17. In-hospital mortality analysis in patients with proximal femoral fracture operatively treated by hip arthroplasty procedure

    Directory of Open Access Journals (Sweden)

    Starčević Srdjan

    2016-01-01

    Full Text Available Background/Aim. Hip fracture remains the leading cause of death in trauma among elderly population and is a great burden to national health services. In-patient death analysis is important to evaluate risk factors, make appropriate selection and perform adequate treatment of infections for patients to be operated. The aim of this study was to analyze in-hospital mortality in proximal femoral fracture patients operatively treated with hip arthroplasty procedure. Methods. We followed 622 consecutive patients, and collected data about age, gender, the presence of infection preoperatively and postoperatively, American Society of Anesthesiologists (ASA score, diabetes mellitus and the type of surgical procedure. Postoperative infections included pneumonia, urinary tract infections, surgical site infections and sepsis. Results. We found a statistically significant influence of preoperative and postoperative infection presence for in-patient mortality with relative risk for lethal outcome of 4.53 (95% CI: 1.44-14.22 for patients with preoperative infection and 7.5 (95% CI: 1.90-29.48 for patients with postoperative infection. We did not confirm a statistically significant influence of age, gender, ASA score, diabetes mellitus or the type of surgical procedure for increased mortality rate. Conclusion. Adequate preoperative selection, risk evaluation and adequate treatment of infections are of the key importance for lowering the risk of death in patients operated due to proximal femoral fracture and treated by hip arthroplasty procedures. Special attention is to be paid for the presence of preoperative and postoperative infections in patients operatively treated due to the risk for increased in-hospital mortality.

  18. CT-guided percutaneous aspiration of Tarlov cyst as a useful diagnostic procedure prior to operative intervention.

    Science.gov (United States)

    Lee, J-Y; Impekoven, P; Stenzel, W; Löhr, M; Ernestus, R-I; Klug, N

    2004-07-01

    Tarlov or perineural cysts are lesions of the nerve root most often found in the sacral region. Several authors recommend surgical treatment of symptomatic Tarlov cysts. However, successful surgical treatment is dependent on appropriate patient selection. In this article, we report three cases of a sacral perineural cyst, causing sciatic pain, and emphasize the usefulness of CT-guided percutaneous aspiration as an important diagnostic and prognostic procedure prior to definitive operative treatment.

  19. Cost Effective, Ultra Sensitive Groundwater Monitoring for Site Remediation and Management: Standard Operating Procedures with QA/QC

    Science.gov (United States)

    2015-05-01

    GUIDANCE DOCUMENT Cost-Effective, Ultra-Sensitive Groundwater Monitoring for Site Remediation and Management: Standard Operating Procedures... Groundwater Monitoring for Site Remediation and Management 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Halden, R.U., Roll, I.B. 5d...DEPLOYMENT WORK As with any groundwater sampling method, the decision to apply the IS2 technology is based on the site characteristics and the type

  20. Aircraft noise reduction technology. [to show impact on individuals and communities, component noise sources, and operational procedures to reduce impact

    Science.gov (United States)

    1973-01-01

    Aircraft and airport noise reduction technology programs conducted by NASA are presented. The subjects discussed are: (1) effects of aircraft noise on individuals and communities, (2) status of aircraft source noise technology, (3) operational procedures to reduce the impact of aircraft noise, and (4) NASA relations with military services in aircraft noise problems. References to more detailed technical literature on the subjects discussed are included.

  1. Gastric emptying after a new, more physiological anti-obesity operation: the Magenstrasse and Mill procedure

    Energy Technology Data Exchange (ETDEWEB)

    Carmichael, A.R.; Johnston, D.; Barker, M.C.J.; Bury, R.F.; Boyce, J.; Sue-Ling, H. [Leeds General Infirmary (United Kingdom)

    2001-09-01

    The Magenstrasse and Mill (M and M) procedure for obesity is designed to preserve normal gastric emptying mechanisms. The hypothesis investigated in this study was that gastric emptying would be normal after the M and M gastroplasty. Gastric emptying studies were performed using both liquid and solid test meals, in ten morbidly obese patients (MO group) and in 13 patients after the M and M procedure (MM group). Seven people of normal weight served as controls and were matched for age, sex and height to the M and M and MO groups. Three years after the M and M procedure, mean (SD) weight loss was 42 (19) kg, with a mean loss of excess weight of 58% (20%). Gastric emptying half-times (t{sub 1/2}) are expressed in minutes, as median values (25th and 75th percentiles). The t{sub 1/2} for solids was 97 (85-110) min in the control group, 140 (86-220) min in the MO group and 79 (46-150) min in the MM group. Median gastric emptying for solids was 0.7% (0.6%-0.8%) per minute in the control group, 0.5% (0.3%-0.8%) in the MO group and 0.9% (0.4%-1.4%) in the M and M group. There were no statistically significant differences in the emptying times of the three groups. It is concluded that the M and M procedure achieves acceptable weight loss, while preserving gastric emptying mechanisms and thus minimising possible side-effects such as vomiting, dumping and diarrhoea, which are common complications of gastric bypass procedures. (orig.)

  2. 过表达沙门氏菌效应蛋白SopB对HeLa细胞骨架的影响%Role of Salmonella Effector SopB Overexpression on the Cytoskeleton of HeLa Cells

    Institute of Scientific and Technical Information of China (English)

    阮海华; 赵霞; 张振奇

    2013-01-01

    [目的]研究沙门氏菌感染宿州细胞过程中,沙门氏菌Ⅲ型分泌系统的效应蛋白SopB对宿主细胞细胞骨架的影响,同时寻找SopB蛋白调控细胞骨架变化的相关结构域.[方法]利用基因克隆的方法分别构建含鼠伤寒沙门氏菌LT2效应蛋白SopB的全长基因、SopBN末端基因片段及SopB肌醇磷脂酶活性中心氨基酸C460突变体的重组质粒,使其均在HeLa细胞中过量表达,对表达结果进行检测.[结果] SopB重组质粒在HeLa细胞中均能正常表达,其中Sopa蛋白的过表达能显著改变HeLa细胞的细胞骨架,使细胞由正常的细胞形态转变为圆形.[结论]通过比较SopB各基因片段对细胞形态的影响,发现SopB过表达在改变HeLa细胞骨架方面与其N末端第46~ 112位氨基酸残基间的肽断直接相关,而与其肌醇磷脂酶活性关系不大.

  3. Primaer brystrekonstruktion i forbindelse med mastektomi ved mammacancer. Indikation, procedure og umiddelbare operative resultater

    DEFF Research Database (Denmark)

    Elberg, J J; Mollerup, C L; Dahlstrøm, K K;

    2000-01-01

    Mastectomy and immediate reconstruction of 122 breasts were performed in 109 patients in close collaboration between plastic surgeons and general surgeons. In 56 patients reconstruction was performed using tissue expanders including 13 bilateral operations, 29 patients had a latissimus dorsi...

  4. Aircraft Configuration and Flight Crew Compliance with Procedures While Conducting Flight Deck Based Interval Management (FIM) Operations

    Science.gov (United States)

    Shay, Rick; Swieringa, Kurt A.; Baxley, Brian T.

    2012-01-01

    Flight deck based Interval Management (FIM) applications using ADS-B are being developed to improve both the safety and capacity of the National Airspace System (NAS). FIM is expected to improve the safety and efficiency of the NAS by giving pilots the technology and procedures to precisely achieve an interval behind the preceding aircraft by a specific point. Concurrently but independently, Optimized Profile Descents (OPD) are being developed to help reduce fuel consumption and noise, however, the range of speeds available when flying an OPD results in a decrease in the delivery precision of aircraft to the runway. This requires the addition of a spacing buffer between aircraft, reducing system throughput. FIM addresses this problem by providing pilots with speed guidance to achieve a precise interval behind another aircraft, even while flying optimized descents. The Interval Management with Spacing to Parallel Dependent Runways (IMSPiDR) human-in-the-loop experiment employed 24 commercial pilots to explore the use of FIM equipment to conduct spacing operations behind two aircraft arriving to parallel runways, while flying an OPD during high-density operations. This paper describes the impact of variations in pilot operations; in particular configuring the aircraft, their compliance with FIM operating procedures, and their response to changes of the FIM speed. An example of the displayed FIM speeds used incorrectly by a pilot is also discussed. Finally, this paper examines the relationship between achieving airline operational goals for individual aircraft and the need for ATC to deliver aircraft to the runway with greater precision. The results show that aircraft can fly an OPD and conduct FIM operations to dependent parallel runways, enabling operational goals to be achieved efficiently while maintaining system throughput.

  5. 两种先进的封装技术--SOC和SOP%The Both Advantages Packaging Tehnology with SOC and SOP

    Institute of Scientific and Technical Information of China (English)

    胡志勇

    2004-01-01

    为了能够实现通过集成所获得的优点,像高性能、低价格、较小的接触面、电源管理和缩短产品进入市场的时间,出现了针对晶圆级的系统级芯片(system on a chip简称SOC)和针对组件级的系统级组件(system on a pakage简称SOP).本文介绍了SOC和SOP的益处、功能和优点.

  6. Analysis of PMD and PDL effect on Chirped Gaussian and SuperGaussain pulse shapes by controlling SOP in SMF

    Directory of Open Access Journals (Sweden)

    VINAYAGAPRIYA.S

    2014-05-01

    Full Text Available In this paper, a numerical analysis of impairments due to PMD and PDL on system performance is investigated in High Speed Optical Communication System. Optical Polarization has pronounced effect on signal quality. Thus there is a need to control the State of Polarization (SOP. Pulse Broadening can be controlled by launching the light signal in particular State of Polarization such as Linear and Circular. Two types of Pulses such as Chirped Gaussian and Supergaussian pulses are launched at different SOP into the optical fiber and it is found that maximum pulse width reduction is achieved when the pulse is at Circular SOP than that of Linear SOP. Also results clearly show that with PMD and PDL, pulse width ratio of Chirped Gaussian pulse is much reduced than that of Chirped Supergaussian Pulse.

  7. French Frigate Shoals (Kanemiloha'i) Biological Monitoring SOP Supplement: Field Guide to Data Management

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This supplement provides a summary version of the FFS Biological Program Standard Operating Procedures (January 2012 version) specifically focusing on key points and...

  8. Landmine-detection rats: an evaluation of reinforcement procedures under simulated operational conditions.

    Science.gov (United States)

    Mahoney, Amanda; Lalonde, Kate; Edwards, Timothy; Cox, Christophe; Weetjens, Bart; Poling, Alan

    2014-05-01

    Because the location of landmines is initially unknown, it is impossible to arrange differential reinforcement for accurate detection of landmines by pouched rats working on actual minefields. Therefore, provision must be made for maintenance of accurate responses by an alternative reinforcement strategy. The present experiment evaluated a procedure in which a plastic bag containing 2,4,6-trinitrotoluene (TNT), the active ingredient in most landmines, was placed in contact with the ground in a disturbed area, then removed, to establish opportunities for reinforcement. Each of five rats continued to accurately detect landmines when extinction was arranged for landmine-detection responses and detections of TNT-contaminated locations were reinforced under a fixed-ratio 1 schedule. The results of this translational research study suggest that the TNT-contamination procedure is a viable option for arranging reinforcement opportunities for rats engaged in actual landmine-detection activities and the viability of this procedure is currently being evaluated on minefields in Angola and Mozambique.

  9. A Guide for Developing Standard Operating Job Procedures for the Tertiary Chemical Treatment - Lime Precipitation Process Wastewater Treatment Facility. SOJP No. 6.

    Science.gov (United States)

    Petrasek, Al, Jr.

    This guide describes the standard operating job procedures for the tertiary chemical treatment - lime precipitation process of wastewater treatment plants. Step-by-step instructions are given for pre-start up, start-up, continuous operation, and shut-down procedures. In addition, some theoretical material is presented along with some relevant…

  10. A Formally Specified Type System and Operational Semantics for Higher-Order Procedural Variables

    CERN Document Server

    Crolard, Tristan

    2009-01-01

    We formally specified the type system and operational semantics of LOOPw with Ott and Isabelle/HOL proof assistant. Moreover, both the type system and the semantics of LOOPw have been tested using Isabelle/HOL program extraction facility for inductively defined relations. In particular, the program that computes the Ackermann function type checks and behaves as expected. The main difference (apart from the choice of an Ada-like concrete syntax) with LOOPw comes from the treatment of parameter passing. Indeed, since Ott does not currently fully support alpha-conversion, we rephrased the operational semantics with explicit aliasing in order to implement the out parameter passing mode.

  11. A general procedure for estimating dynamic displacements using strain measurements and operational modal analysis

    DEFF Research Database (Denmark)

    Skafte, Anders; Aenlle, Manuel L.; Brincker, Rune

    2016-01-01

    measuring the in-plane deformation. This paper proposes a method in which the displacement mode shapes and responses can be predicted using only strain measurements. The method relies on the newly discovered principle of local correspondence, which states that each experimental mode can be expressed....... The method is validated with experimental tests on a scaled model of a two-span bridge installed with strain gauges. Random load was applied to simulate a civil structure under operating condition, and strain mode shapes were identified using operational modal analysis....

  12. New Procedure to Derive the Performance Indices Associated with Reservoir Operation Rule

    Institute of Scientific and Technical Information of China (English)

    WANG Jin-wen; ZHANG Yong-chuan; ZHANG You-quan

    2002-01-01

    Stochastic dynamic programming (SDP) is extensively used in the optimization for long-term reservoir operations. Generally, both of the steady state optimal policy and its associated performance indices (PIs) for multipurpose reservoir are of prime importance. To derive the PIs there are two typical ways: simulation and probability formula. Among the disadvantages, one is that these approaches require the pre-specified operation policy. IHuminated by the convergence of objective function in SDP, a new approach, which has the advantage that its use can be concomitant with the solving of SDP, is proposed to determine the desired PIs. In the case study, its efficiency is also practically tested.

  13. 标准化作业流程(SOP)的理解与实践

    Institute of Scientific and Technical Information of China (English)

    陈靖华

    2012-01-01

      余世维在他的讲座中特别提到:“一个公司要有两本书,一本书是红皮书,是公司的策略,即作战指导纲领;另一本书是蓝皮书,即SOP,标准作业程序,而且这个标准作业程序一定要做到细化和量化。”本文结合实践就SOP 的概念、编制、推进与应用进行了简要论述。

  14. Upgrades to the VISAR-streaked optical pyrometer (SOP) system on NIF

    Science.gov (United States)

    Manuel, A. M.; Millot, M.; Seppala, L. G.; Frieders, G.; Zeid, Z.; Christensen, K.; Celliers, P. M.

    2015-08-01

    The Velocity Interferometer System for Any Reflector (VISAR) is a critical diagnostic in Inertial Confinement Fusion and High Energy Density research as it has the ability to track shock fronts or interfaces moving 0.1-100 km/s with great accuracy. At the National Ignition Facility (NIF), the VISAR has recently been used successfully for implosion tuning and equation of state measurements. However, the initial design of the companion Streaked Optical Pyrometer (SOP) to measure spectral radiance - hence shock temperature - suffers from large background levels and poor spatial resolution. We report on an upgrade to improve the spatial resolution in the 560-640nm band by using custom lenses and replacing the Dove prism with a K-mirror and implementing a gating-circuit for the streak camera to reduce background signal. We envision that upgraded SOP will provide high quality data collection matching NIF VISAR's standards.

  15. Operation EAGLE CLAW: Pioneer of Modern Aviation Tactics, Techniques and Procedures

    Science.gov (United States)

    2010-03-17

    The Iran Hostage Rescue Mission," Air & Space Power Journal- Espanol , Fall 2006. Kyle, James H., and John Robert Edison. The Guts to Try: The Untold...Kamps, "Operation EAGLE CLAW: The Iran Hostage Rescue Mission," Air & Space Power Journal- Espanol , (Fall 2006), 1. 5 Rapid Ground Refueling is the

  16. Exploring Mathematical Reasoning of the Order of Operations: Rearranging the Procedural Component PEMDAS

    Science.gov (United States)

    Lee, Jae Ki; Licwinko, Susan; Taylor-Buckner, Nicole

    2013-01-01

    PEMDAS is a mnemonic device to memorize the order in which to calculate an expression that contains more than one operation. However, students frequently make calculation errors with expressions, which have either multiplication and division or addition and subtraction next to each other. This article explores the mathematical reasoning of the…

  17. 46 CFR 281.1 - Information and procedure required under liner operating-differential subsidy agreements.

    Science.gov (United States)

    2010-10-01

    ...) representing interest on vessels shall be allocated to vessels and voyages in the same ratio that depreciation... forward necessary instructions and forms to be used. (f) Current financial reports. Each operator shall prepare current financial reports as specified in this paragraph and shall submit one copy each to...

  18. 40 CFR 63.1104 - Process vents from continuous unit operations: applicability assessment procedures and methods.

    Science.gov (United States)

    2010-07-01

    ... vent. (iv) Design analysis based on accepted chemical engineering principles, measurable process... be monitored to ensure the process vent is operated in conformance with its design or process and... 40 Protection of Environment 10 2010-07-01 2010-07-01 false Process vents from continuous...

  19. Hypersensitivity and pain induced by operative procedures and the "cracked tooth" syndrome.

    Science.gov (United States)

    Seltzer, S; Boston, D

    1997-01-01

    Various dental conditions are responsible for tooth hypersensitivity and pain. They include hypersensitive dentin; the "cracked tooth" syndrome; pulp and periapical irritation, inflammation and/or degeneration; barodontalgia (aerodontalgia); and periodontal pathoses, particularly the pulpal-periodontal syndrome. Each operative condition is reviewed with respect to its etiology, symptomatology, and diagnosis. Some treatment recommendations are made to prevent or reduce symptoms.

  20. Evaluation of the ability of mice to detect VOCs, using a positive operant reinforcement procedure.

    Science.gov (United States)

    Hojo, Rieko

    2015-08-01

    To examine the validity of a newly established "three-odor detection (TOD)" procedure using one of volatile organic compounds (VOCs), limonene, food-restricted male mice were used. Five animals each were assigned to either TOD or single-odor detection (SOD). TOD was composed of two trainings and one test (TEST) session. Mice were trained to discriminate an odor of coffee from no odor and odors of coffee and cheese from no odor in trainings 1 and 2, respectively. In TEST, mice were required to discriminate odors of coffee, cheese, and limonene from no odor. In SOD, mice were required to discriminate an odor of limonene from no odor. Each training or test was conducted once a day until animals achieved a learning criterion (75% correct response rate for 2 consecutive days), or until a maximum number of sessions (20 sessions) was completed. The number of sessions for reaching the learning criterion of animals in TEST (8.2 ± 0.8) was smaller than that of animals in SOD (19.2 ± 0.8). Results indicated that mice in TOD detected low levels of VOCs more rapidly than animals in SOD. I concluded that TOD is a useful procedure for detecting low levels of VOCs.

  1. 浅谈GLP实验室标准操作规程(SOP)

    Institute of Scientific and Technical Information of China (English)

    周忠光; 朴成玉; 姜金奇; 史松林; 赵春晓; 付清遥; 朱丽华

    2012-01-01

      标准操作规程(SOP)是构建药物安全性评价研究机构的关键组成部分,通过对SOP的特点、SOP的基本内容、SOP文件的管理进行简单的论述,加强对SOP的认识。

  2. Environmental Consequences of Nanotechnologies: Nanoparticle Dispersion in Aqueous Media: SOP-T-1

    Science.gov (United States)

    2015-02-01

    ER D C/ EL S R- 15 -2 Environmental Consequences of Nanotechnologies Nanoparticle Dispersion in Aqueous Media: SOP-T-1 En vi ro nm en...dispersions of nanoparticles (NPs) for use in bioassay media for exposures/characterizations are a crucial need in ecotoxicology assays. The present...protocol provides guidance and step-by-step methods for: (1) creating a working stock from nanoparticle powder and nanoparticle aqueous suspensions

  3. CONTRIBUTIONS FROM SMOKE ON IMPACT OF WELDING PROCEDURES HEALTH OPERATORS WELDER

    Directory of Open Access Journals (Sweden)

    Gheorghe AMZA

    2012-05-01

    Full Text Available This paper presents research conducted on the contents of fumes resulting from welding processes with emphasis on micro various metallic and nonmetallic elements involved in these fumes. It also presents the main health effects of welders and operators working in the welding stations. Are risks that may occur due to micro chromium, nickel, iron, manganese, silicon, fluorine, zinc, aluminum, copper, cadmium, lead, molybdenum, cobalt, vanadium and others.

  4. Joint Doctrine, Tactics, Techniques, and Procedures for Meteorological and Oceanographic Operations

    Science.gov (United States)

    2007-11-02

    Aerodrome Forecasts Tidal Data Thickness, 1000-500mb Thunderstorms Tropical Storm Advisories Tropopause Heights and/or Winds Upper Air Charts Upper Air...Sigonella, Sicily . The data for these products originate from NAVEURMETOCCEN. b. METOC dial-in systems can also be used for early-in operations or as...studies, and tabular publications. CD-ROM products include selected global station climatic summaries (ISMCS), global tropical atlases, global upper air

  5. Standard operating procedure for the good manufacturing practice-compliant production of human bone marrow mesenchymal stem cells.

    Science.gov (United States)

    Roseti, Livia; Serra, Marta; Bassi, Alessandra

    2015-01-01

    According to the European Regulation (EC 1394/2007), Mesenchymal Stem Cells expanded in culture for clinical use are considered as Advanced Therapy Medicinal Products. As a consequence, they must be produced in compliance with Good Manufacturing Practice in order to ensure safety, reproducibility, and efficacy. Here, we report a Standard Operating Procedure describing the Good Manufacturing Practice-compliant production of Bone Marrow-derived Mesenchymal Stem Cells suitable for autologous implantation in humans. This procedure can be considered as a template for the development of investigational medicinal Mesenchymal Stem Cells-based product protocols to be enclosed in the dossier required for a clinical trial approval. Possible clinical applications concern local uses in the regeneration of bone tissue in nonunion fractures or in orthopedic and maxillofacial diseases characterized by a bone loss.

  6. Double Endoscopic Intraluminal Operation (DEILO) for Early Gastric Cancer: Outcome of Novel Procedure for Endoscopic Submucosal Dissection.

    Science.gov (United States)

    Ogata, Kyoichi; Yanai, Mitsuhiro; Kuriyama, Kengo; Suzuki, Masaki; Yanoma, Toru; Kimura, Akiharu; Kogure, Norimichi; Toyomasu, Yoshitaka; Ohno, Tetsuro; Mochiki, Erito; Kuwano, Hiroyuki

    2017-01-01

    Endoscopic submucosal dissection (ESD) has been used to treat patients with early gastric cancer (EGC). Although several endoscopic devices have been developed to ensure easy and safe ESD, this technique still requires an experienced, highly skilled endoscopist, as it is performed through a single gastroscope, thus requiring one-handed surgical techniques. To overcome these limitations, many ESD procedures with counter-traction have been developed, such as the double scope, double channel scope, clip with line, magnetic anchor, percutaneous traction and external grasping forceps methods. We devised a double endoscopic intraluminal operation (DEILO). Two endoscopes were simultaneously inserted into the stomach. One endoscope was used to lift the lesion, and the other was used to excise the lesion. The DEILO procedure was performed on 122 cases of EGC. In this article, we report the efficacy and safety of DEILO in patients with EGC.

  7. Accuracy of axial depth of cut in micromilling operations - Simplified procedure and uncertainty model

    DEFF Research Database (Denmark)

    Bissacco, Giuliano

    2005-01-01

    and their rapid warming and cooling, which prevent the achievement of a steady state. Several other factors, independent on the tool-workpiece interaction, influence the machining accuracy. The cutting parameter most heavily affected is the axial depth of cut which is the most critical when using micro end mills......, due to the easy breakage particularly when milling on hard materials [1]. Typical values for the errors on the control of the axial depth of cut are in the order of 50 microns, while the aimed depth of cut can be as low as 5 microns. The author has developed a machining procedure for optimal control......In order to maintain an optimum cutting speed, the reduction of mill diameters requires machine tools with high rotational speed capabilities. A solution to update existing machine tools is the use of high speed attached spindles. Major drawbacks of these attachments are the high thermal expansion...

  8. Adoption of the hybrid CTO approach by a single non-CTO operator: procedural and clinical outcomes.

    Science.gov (United States)

    Vo, Minh N; McCabe, James M; Lombardi, William L; Ducas, John; Ravandi, Amir; Brilakis, Emmanouil S

    2015-03-01

    The feasibility of adopting the "hybrid" approach by a single operator without prior experience in percutaneous coronary intervention (PCI) of chronic total occlusions (CTOs) has not been described. Consecutive patients who underwent CTO-PCI by a single operator using the "hybrid" approach between 2012 and 2013 formed the analytic cohort. No patient was declined on the basis of angiographic findings. Clinical and angiographic characteristics together with procedural and hospital outcomes are described. During the study period, a total of 48 consecutive patients underwent PCI of 50 CTOs. Mean age was 63.4 ± 9.4 years and most patients (83%) were men. The right coronary artery (RCA) was the most commonly treated CTO vessel (54%) and mean J-CTO score was 2.3 ± 1.1. A primary retrograde approach was chosen for 33% of lesions and 40% required use of an epicardial collateral vessel. The primary strategy was effective in 65% of successful cases, 35% required one change in strategy, and 15% requiring two strategy changes. Procedural success rate was 92%. The median number of stents used was 3 (interquartile range [IQR], 2-4] and the total stent length was 73 mm [IQR, 38-96 mm). Mean contrast volume was 356.4 ± 148.3 mL and the mean air kerma radiation exposure was 3.5 ± 2.0 Gy. No patient experienced a major periprocedural complication. The "hybrid" approach to CTO-PCI can be successfully adopted by a single operator with excellent early procedural success and low complication rates, despite a lack of prior CTO-PCI experience.

  9. Numerical simulation of the transient thermal-hydraulic behaviour of the ITER blanket cooling system under the draining operational procedure

    Energy Technology Data Exchange (ETDEWEB)

    Di Maio, P.A. [Dipartimento di Energia, Ingegneria dell’Informazione e Modelli Matematici, Università di Palermo Viale delle Scienze, 90128 Palermo (Italy); Dell’Orco, G.; Furmanek, A. [ITER Organization, Route de Vinon-sur-Verdon, CS 90 046, 13067 St Paul Lez Durance Cedex (France); Garitta, S. [Dipartimento di Energia, Ingegneria dell’Informazione e Modelli Matematici, Università di Palermo Viale delle Scienze, 90128 Palermo (Italy); Merola, M.; Mitteau, R.; Raffray, R. [ITER Organization, Route de Vinon-sur-Verdon, CS 90 046, 13067 St Paul Lez Durance Cedex (France); Spagnuolo, G.A. [Dipartimento di Energia, Ingegneria dell’Informazione e Modelli Matematici, Università di Palermo Viale delle Scienze, 90128 Palermo (Italy); Vallone, E., E-mail: eug.vallone@gmail.com [Dipartimento di Energia, Ingegneria dell’Informazione e Modelli Matematici, Università di Palermo Viale delle Scienze, 90128 Palermo (Italy)

    2015-10-15

    Highlights: • ITER blanket cooling system hydraulic behaviour is studied under draining transient. • A computational approach based on the finite volume method has been followed. • Draining efficiency has been assessed in term of transient duration and residual water. • Transient duration ranges from ∼40 to 50 s, under the reference draining scenario. • Residual water is predicted to range from few tens of gram up to few kilograms. - Abstract: Within the framework of the research and development activities supported by the ITER Organization on the blanket system issues, an intense analysis campaign has been performed at the University of Palermo with the aim to investigate the thermal-hydraulic behaviour of the cooling system of a standard 20° sector of ITER blanket during the draining transient operational procedure. The analysis has been carried out following a theoretical-computational approach based on the finite volume method and adopting the RELAP5 system code. In a first phase, attention has been focused on the development and validation of the finite volume models of the cooling circuits of the most demanding modules belonging to the standard blanket sector. In later phase, attention has been put to the numerical simulation of the thermal-hydraulic transient behaviour of each cooling circuit during the draining operational procedure. The draining procedure efficiency has been assessed in terms of both transient duration and residual amount of coolant inside the circuit, observing that the former ranges typically between 40 and 120 s and the latter reaches at most ∼8 kg, in the case of the cooling circuit of twinned modules #6–7. Potential variations to operational parameters and/or to circuit lay-out have been proposed and investigated to optimize the circuit draining performances. In this paper, the set-up of the finite volume models is briefly described and the key results are summarized and critically discussed.

  10. FINANCIAL INDICATORS FOR THE IMPLEMENTATION OF AN EUROPEAN FUNDED INVESTMENT PROJECT UNDER SOP IEC PROGRAMME – CASE STUDY OF A ROMANIAN SME

    Directory of Open Access Journals (Sweden)

    Droj Laurentiu

    2010-07-01

    Full Text Available The European Integration came with new challenges for the Romanian enterprises especially for the SMEs, the opportunities arising from operating on the European Single Market and the possibility for accession of European Regional Development Funds. The main programme designed to offer access for small, medium and large Romanian enterprises to European funding is the Sectorial Operational Programme “Increase of Economic Competitiveness”- SOP IEC. This paper will analyze the area of intervention “D1.1. Productive and environment friendly investments and preparation for market competition in which Romanian SMEs” are competing to access European funding in order to develop their activities or to extend them into new ones. One of the main challenges for these SMEs is to generate, fulfil and to respect the financial indicators of the programme, which are part of the financial analysis of the project.

  11. Design data package and operating procedures for MSFC solar simulator test facility

    Science.gov (United States)

    1981-01-01

    Design and operational data for the solar simulator test facility are reviewed. The primary goal of the facility is to evaluate the performance capacibility and worst case failure modes of collectors, which utilize either air or liquid transport media. The facility simulates environmental parameters such as solar radiation intensity, solar spectrum, collimation, uniformity, and solar attitude. The facility also simulates wind conditions of velocity and direction, solar system conditions imposed on the collector, collector fluid inlet temperature, and geometric factors of collector tilt and azimuth angles. Testing the simulator provides collector efficiency data, collector time constant, incident angle modifier data, and stagnation temperature values.

  12. CCSDS遥控通信操作规程应用%Application of Communications Operation Procedure-1

    Institute of Scientific and Technical Information of China (English)

    刘鑫; 闫春香; 王凤宇

    2012-01-01

    由于遥控通信的重要性,为了在有噪声的链路空间中可靠地传输遥控数据,CCSDS(空间数据系统咨询委员会)提供了遥控COP-1(通信操作规程)建议书.该操作规程使用遥控空间链路协议,规定了空间任务中地—空或空—空通信链路间应用数据的自动重传操作规程,保证了用户业务数据的正确传输.此外,还介绍了CCSDS标准建议书中的遥控通信操作规程的概念、业务类型,并对其中使用的内部规程接口、业务数据传输操作规程以及滑动窗口的应用进行了详细说明.%CCSDS (Consultative Committee for Space Data Systems) provides COP-1 (Communications Operations Procedure-1) technical recommendation for reliable transmission of telecommand data over space communications links with the presence of noise. The procedure used with telecommand space data link protocol provides an automatic retransmission procedure to be used by space missions to transfer space application data over a ground-to-space or space-to-space communications link, and assures correctness of service data delivery. The paper introduces the concept of COP-1, service types, and describes the application of inter-procedure interfaces, service transmission procedures and sliding window used in the recommendation.

  13. A general procedure for estimating dynamic displacements using strain measurements and operational modal analysis

    Science.gov (United States)

    Skafte, Anders; Aenlle, Manuel L.; Brincker, Rune

    2016-02-01

    Measurement systems are being installed in more and more civil structures with the purpose of monitoring the general dynamic behavior of the structure. The instrumentation is typically done with accelerometers, where experimental frequencies and mode shapes can be identified using modal analysis and used in health monitoring algorithms. But the use of accelerometers is not suitable for all structures. Structures like wind turbine blades and wings on airplanes can be exposed to lightning, which can cause the measurement systems to fail. Structures like these are often equipped with fiber sensors measuring the in-plane deformation. This paper proposes a method in which the displacement mode shapes and responses can be predicted using only strain measurements. The method relies on the newly discovered principle of local correspondence, which states that each experimental mode can be expressed as a unique subset of finite element modes. In this paper the technique is further developed to predict the mode shapes in different states of the structure. Once an estimate of the modes is found, responses can be predicted using the superposition of the modal coordinates weighted by the mode shapes. The method is validated with experimental tests on a scaled model of a two-span bridge installed with strain gauges. Random load was applied to simulate a civil structure under operating condition, and strain mode shapes were identified using operational modal analysis.

  14. Primaer brystrekonstruktion i forbindelse med mastektomi ved mammacancer. Indikation, procedure og umiddelbare operative resultater

    DEFF Research Database (Denmark)

    Elberg, J J; Mollerup, C L; Dahlstrøm, K K

    2000-01-01

    Mastectomy and immediate reconstruction of 122 breasts were performed in 109 patients in close collaboration between plastic surgeons and general surgeons. In 56 patients reconstruction was performed using tissue expanders including 13 bilateral operations, 29 patients had a latissimus dorsi...... received systemic treatment and 10 local radiotherapy as well. There was no complication during systemic therapy related to reconstruction. In 10 cases local radiotherapy was performed in full, with a delay of four weeks in one patient and a need for correction of the radiation field during treatment...... myocutaneous flap and 24 a free transverse rectus abdominis myocutaneous flap. There were 27 postoperative local complications in 122 reconstructions (22%), in five the reconstruction was lost. Only patients clinically in stage I were considered for reconstruction. After histopathological staging 27 patients...

  15. Extended Function of Plasmid Partition Genes: the Sop System of Linear Phage-Plasmid N15 Facilitates Late Gene Expression▿

    Science.gov (United States)

    Ravin, Nikolai V.; Rech, Jérôme; Lane, David

    2008-01-01

    The mitotic stability of the linear plasmid-prophage N15 of Escherichia coli depends on a partition system closely related to that of the F plasmid SopABC. The two Sop systems are distinguished mainly by the arrangement of their centromeric SopB-binding sites, clustered in F (sopC) and dispersed in N15 (IR1 to IR4). Because two of the N15 inverted repeat (IR) sites are located close to elements presumed (by analogy with phage λ) to regulate late gene expression during the lytic growth of N15, we asked whether Sop partition functions play a role in this process. In N15, a putative Q antiterminator gene is located 6 kb upstream of the probable major late promoter and two intrinsic terminator-like sequences, in contrast to λ, where the Q gene is adjacent to the late promoter. Northern hybridization and lacZ reporter activity confirmed the identity of the N15 late promoter (p52), demonstrated antiterminator activity of the Q analogue, and located terminator sequences between p52 and the first open reading frame. Following prophage induction, N15 mutated in IR2 (downstream from gene Q) or IR3 (upstream of p52) showed a pronounced delay in lysis relative to that for wild-type N15. Expression of ir3−-p52::lacZ during N15 wild-type lytic growth was strongly reduced relative to the equivalent ir3+ fusion. The provision of Q protein and the IR2 and SopAB proteins in trans to ir3+-p52::lacZ increased expression beyond that seen in the absence of any one of these factors. These results indicate that the N15 Sop system has a dual role: partition and regulation of late gene transcription during lytic growth. PMID:18359814

  16. Extended function of plasmid partition genes: the Sop system of linear phage-plasmid N15 facilitates late gene expression.

    Science.gov (United States)

    Ravin, Nikolai V; Rech, Jérôme; Lane, David

    2008-05-01

    The mitotic stability of the linear plasmid-prophage N15 of Escherichia coli depends on a partition system closely related to that of the F plasmid SopABC. The two Sop systems are distinguished mainly by the arrangement of their centromeric SopB-binding sites, clustered in F (sopC) and dispersed in N15 (IR1 to IR4). Because two of the N15 inverted repeat (IR) sites are located close to elements presumed (by analogy with phage lambda) to regulate late gene expression during the lytic growth of N15, we asked whether Sop partition functions play a role in this process. In N15, a putative Q antiterminator gene is located 6 kb upstream of the probable major late promoter and two intrinsic terminator-like sequences, in contrast to lambda, where the Q gene is adjacent to the late promoter. Northern hybridization and lacZ reporter activity confirmed the identity of the N15 late promoter (p52), demonstrated antiterminator activity of the Q analogue, and located terminator sequences between p52 and the first open reading frame. Following prophage induction, N15 mutated in IR2 (downstream from gene Q) or IR3 (upstream of p52) showed a pronounced delay in lysis relative to that for wild-type N15. Expression of ir3(-)-p52::lacZ during N15 wild-type lytic growth was strongly reduced relative to the equivalent ir3(+) fusion. The provision of Q protein and the IR2 and SopAB proteins in trans to ir3(+)-p52::lacZ increased expression beyond that seen in the absence of any one of these factors. These results indicate that the N15 Sop system has a dual role: partition and regulation of late gene transcription during lytic growth.

  17. Development and application of procedures to evaluate air quality and visibility impacts of low-altitude flying operations

    Energy Technology Data Exchange (ETDEWEB)

    Liebsch, E.J.

    1990-08-01

    This report describes the development and application of procedures to evaluate the effects of low-altitude aircraft flights on air quality and visibility. The work summarized in this report was undertaken as part of the larger task of assessing the various potential environmental impacts associated with low-altitude military airspaces. Accomplishing the air quality/visibility analysis for the GEIS included (1) development and application of an integrated air quality model and aircraft emissions database specifically for Military Training Route (MTR) or similar flight operations, (2) selection and application of an existing air quality model to analyze the more widespread and less concentrated aircraft emissions from military Operations Areas (MOAs) and Restricted Areas (RAs), and (3) development and application of procedures to assess impacts of aircraft emissions on visibility. Existing air quality models were considered to be inadequate for predicting ground-level concentrations of pollutants emitted by aircraft along MTRs; therefore, the Single-Aircraft Instantaneous Line Source (SAILS) and Multiple-Aircraft Instantaneous Line Source (MAILS) models were developed to estimate potential impacts along MTRs. Furthermore, a protocol was developed and then applied in the field to determine the degree of visibility impairment caused by aircraft engine exhaust plumes. 19 refs., 2 figs., 3 tabs.

  18. Effect of the video output of the dental operating microscope on anxiety levels in a pediatric population during restorative procedures.

    Science.gov (United States)

    Sayed, Abrar; Ranna, Vinisha; Padawe, Dimple; Takate, Vilas

    2016-01-01

    Adapting a child to the alien settings of a dental operatory is a major challenge to the dentist. Fear of the unknown and preconceived notions of dental pain causes anxiety in the pediatric patient. This often leads to disruptive and uncooperative behavior in the dental operatory. Many methods of behavior management have been described, of which the Tell-Show-Do (TSD) is an established and time-tested technique of behavior management. To determine if a live visual output of the dental operating microscope (DOM) could be used as an adjunct to the TSD technique, to involve the child more completely in the procedure and reduce the fear of the unknown. The study was a randomized, controlled, crossover, and cross-sectional clinical trial. Data were obtained from two visits. 90 children having carious lesions on both lower first molars, in the 7-9 years age group were selected and divided randomly into two groups. Restorative procedures were performed on one tooth per visit, with visits 1 week apart. Live display of the procedure was shown to the patient using video output of the DOM displayed on a 72 inch LCD monitor, angled for best visibility of the child. Anxiety levels were evaluated using Venhams picture selection test and pulse oximetry. Student's t-test was used to compare the anxiety scores obtained from the two groups. The results showed there was a decrease in the anxiety from the first visit to the second visit. (P = 0.05 for Group A and P = 0.003 for Group B). The patients preferred the visit in which the DOM was used. The operator reported an increased patient compliance and reduced patient movement in the visits in which the DOM was used. There is a reduction in anxiety from the first visit to the second visit for restorative treatment when the DOM is used.

  19. Effect of the video output of the dental operating microscope on anxiety levels in a pediatric population during restorative procedures

    Directory of Open Access Journals (Sweden)

    Abrar Sayed

    2016-01-01

    Full Text Available Background: Adapting a child to the alien settings of a dental operatory is a major challenge to the dentist. Fear of the unknown and preconceived notions of dental pain causes anxiety in the pediatric patient. This often leads to disruptive and uncooperative behavior in the dental operatory. Many methods of behavior management have been described, of which the Tell-Show-Do (TSD is an established and time-tested technique of behavior management. Aim: To determine if a live visual output of the dental operating microscope (DOM could be used as an adjunct to the TSD technique, to involve the child more completely in the procedure and reduce the fear of the unknown. Materials and Methods: The study was a randomized, controlled, crossover, and cross-sectional clinical trial. Data were obtained from two visits. 90 children having carious lesions on both lower first molars, in the 7-9 years age group were selected and divided randomly into two groups. Restorative procedures were performed on one tooth per visit, with visits 1 week apart. Live display of the procedure was shown to the patient using video output of the DOM displayed on a 72 inch LCD monitor, angled for best visibility of the child. Anxiety levels were evaluated using Venhams picture selection test and pulse oximetry. Statistical Analysis: Student′s t-test was used to compare the anxiety scores obtained from the two groups. Results: The results showed there was a decrease in the anxiety from the first visit to the second visit. (P = 0.05 for Group A and P = 0.003 for Group B. The patients preferred the visit in which the DOM was used. The operator reported an increased patient compliance and reduced patient movement in the visits in which the DOM was used. Conclusion: There is a reduction in anxiety from the first visit to the second visit for restorative treatment when the DOM is used.

  20. Colloidal Fouling of Nanofiltration Membranes: Development of a Standard Operating Procedure

    Science.gov (United States)

    Al Mamun, Md Abdullaha; Bhattacharjee, Subir; Pernitsky, David; Sadrzadeh, Mohtada

    2017-01-01

    Fouling of nanofiltration (NF) membranes is the most significant obstacle to the development of a sustainable and energy-efficient NF process. Colloidal fouling and performance decline in NF processes is complex due to the combination of cake formation and salt concentration polarization effects, which are influenced by the properties of the colloids and the membrane, the operating conditions of the test, and the solution chemistry. Although numerous studies have been conducted to investigate the influence of these parameters on the performance of the NF process, the importance of membrane preconditioning (e.g., compaction and equilibrating with salt water), as well as the determination of key parameters (e.g., critical flux and trans-membrane osmotic pressure) before the fouling experiment have not been reported in detail. The aim of this paper is to present a standard experimental and data analysis protocol for NF colloidal fouling experiments. The developed methodology covers preparation and characterization of water samples and colloidal particles, pre-test membrane compaction and critical flux determination, measurement of experimental data during the fouling test, and the analysis of that data to determine the relative importance of various fouling mechanisms. The standard protocol is illustrated with data from a series of flat sheet, bench-scale experiments. PMID:28106775

  1. A case method for Sales and Operations Planning: a learning experience from Germany

    OpenAIRE

    Luiz Felipe Scavarda; Bernd Hellingrath; Tobias Kreuter; Antonio Márcio Tavares Thomé; Marcelo Xavier Seeling; Jan-Hendrick Fischer; Raquel Mello

    2017-01-01

    Abstract Adequate preparation, learning, and training is required for Sales and Operations Planning (S&OP) to aid organizations in achieving the full expected benefits from its implementation. This paper presents a case method for S&OP and the learning experience of its application at the University of Münster (Germany). The “constructive alignment principle” was applied with a “team teaching” approach, involving an executive from the case company. Students improved th...

  2. Operational Implementation of the ATOVS Processing Procedure in KMA and Its Validation

    Institute of Scientific and Technical Information of China (English)

    Myoung-Hwan AHN; Mee-Ja KIM; Chu-Yong CHUNG; Ae-Sook SUH

    2003-01-01

    The Korea Meteorological Administration (KMA) has processed the data from the advanced TOVS(ATOVS) onboard NOAA-16 satellite since May 2001. The operational production utilizes the AAPP(ATOVS and AVHRR Processing Package) of EUMETSAT and IAPP (International ATOVS ProcessingPackage) of the University of Wisconsin. For the initial guess profiles, the predicted fields (usually 6 to 12hour forecasted fields) from the global aviation model of NOAA/NCEP are used. The average number ofprofiles retrieved from the ATOVS data is about 1,300 for each morning and afternoon orbit at about 18 and06 UTC, respectively. The retrieved temperature and dew point temperatures are provided to forecastersin real time and used for initialization of prediction models. With the advanced microwave sensor (AMSU;Advanced Microwave Sounding Unit), accuracy of the ATOVS products is expected to be better than thatof the TOVS products, especially in cloudy conditions. Indeed, the preliminary results from a validationstudy with the collocated radiosonde data during a 8-month period, from May to December 2001, for theEast Asia region show an improved accuracy of the ATOVS products for cloudy skies versus the TOVS,especially for higher altitudes. The RMS (Root Mean Square) difference between the ATOVS productsand radiosonde data is about 1.3℃ for both clear and cloudy conditions, except for near the ground and athigher altitudes, at around 200 hPa. There is no significant temporal variation of the error statistics at allpressure levels. In case of the water vapor mixing ratio, the largest difference is shown at lower altitudes,while the accuracy is much better for the clear sky cases than the cloudy sky cases. The bias and RMSEat lower altitudes is about 0.557 g kg-1 and 2.5 g kg-1 and decrease significantly with increasing altitude.

  3. The development of a quantitative measure for the complexity of emergency tasks stipulated in emergency operating procedures of nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jin Kyun; Jung, Won Dea

    2006-11-15

    Previous studies have continuously pointed out that human performance is a decisive factor affecting the safety of complicated process systems. Subsequently, as the result of extensive efforts, it has been revealed that the provision of procedures is one of the most effective countermeasures, especially if human operators have to carry out their tasks under a very stressful environment. That is, since good procedures are helpful to not only enhance the performance of human operators but also the reduction of the possibility of a human error through stipulating detailed tasks to be done by human operators. Ironically, it has been emphasized that the performance of human operators could be impaired due to complicated procedures, because procedures directly govern the physical as well as cognitive behavior of human operators by institutionalizing detailed actions. Therefore, it is a prerequisite to develop a systematic framework that properly evaluate the complexity of tasks described in procedures. For this reason, a measure called TACOM (Task Complexity) that can quantify the complexity of emergency tasks described in the emergency operating procedures (EOPs) of NPPs has been developed. In this report, a technical background as well as practical steps to quantify the complexity of tasks were presented with a series of studies that were conducted to ensure the validity of the TACOM measure. As a result of validation studies, since it is shown that the TACOM measure seem to properly quantify the complexity of emergency tasks, it is desirable that the TACOM measure plays an important role in improving the performance of human operators.

  4. Reliability of SOP Component Solder Joint%小尺寸封装(SOP)器件焊点可靠性研究

    Institute of Scientific and Technical Information of China (English)

    安利全; 郑建明

    2009-01-01

    从器件引脚镀层种类、厚度、焊接参数和焊盘设计等几个方面对小尺寸封装(small outline package,简称SOP)器件焊点可靠性的影响作了分析,给出了提高焊点可靠性的方法,并通过UG软件建立了电路板和SOP焊点的三维有限元模型,进行了SOP器件焊点在近似试验载荷条件下的应力应变三维有限元数值模拟,得出了焊点内部精确的应力应变分布.

  5. 浅谈印刷企业SOP

    Institute of Scientific and Technical Information of China (English)

    刘庆华; 赵连冲

    2008-01-01

    当今社会是一个信息化、多元化的世界,各行各业为了在这个复杂的竞争世界中挤出自己的一席之地,纷纷引进新技术,采用新的管理方式,SOP(Standard Operation Procedure标准作业程序)正是在这样的环境中产生和发展起来的。随着SOP在麦当劳等大型企业中的推广与应用,其他企业也开始密切关注并采用SOP。

  6. Sop-GPU: accelerating biomolecular simulations in the centisecond timescale using graphics processors.

    Science.gov (United States)

    Zhmurov, A; Dima, R I; Kholodov, Y; Barsegov, V

    2010-11-01

    Theoretical exploration of fundamental biological processes involving the forced unraveling of multimeric proteins, the sliding motion in protein fibers and the mechanical deformation of biomolecular assemblies under physiological force loads is challenging even for distributed computing systems. Using a C(α)-based coarse-grained self organized polymer (SOP) model, we implemented the Langevin simulations of proteins on graphics processing units (SOP-GPU program). We assessed the computational performance of an end-to-end application of the program, where all the steps of the algorithm are running on a GPU, by profiling the simulation time and memory usage for a number of test systems. The ∼90-fold computational speedup on a GPU, compared with an optimized central processing unit program, enabled us to follow the dynamics in the centisecond timescale, and to obtain the force-extension profiles using experimental pulling speeds (v(f) = 1-10 μm/s) employed in atomic force microscopy and in optical tweezers-based dynamic force spectroscopy. We found that the mechanical molecular response critically depends on the conditions of force application and that the kinetics and pathways for unfolding change drastically even upon a modest 10-fold increase in v(f). This implies that, to resolve accurately the free energy landscape and to relate the results of single-molecule experiments in vitro and in silico, molecular simulations should be carried out under the experimentally relevant force loads. This can be accomplished in reasonable wall-clock time for biomolecules of size as large as 10(5) residues using the SOP-GPU package.

  7. Field Laboratory in the Osage Reservation -- Determination of the Status of Oil and Gas Operations: Task 1. Development of Survey Procedures and Protocols

    Energy Technology Data Exchange (ETDEWEB)

    Carroll, Herbert B.; Johnson, William I.

    1999-04-27

    Procedures and protocols were developed for the determination of the status of oil, gas, and other mineral operations on the Osage Mineral Reservation Estate. The strategy for surveying Osage County, Oklahoma, was developed and then tested in the field. Two Osage Tribal Council members and two Native American college students (who are members of the Osage Tribe) were trained in the field as a test of the procedures and protocols developed in Task 1. Active and inactive surface mining operations, industrial sites, and hydrocarbon-producing fields were located on maps of the county, which was divided into four more or less equal areas for future investigation. Field testing of the procedures, protocols, and training was successful. No significant damage was found at petroleum production operations in a relatively new production operation and in a mature waterflood operation.

  8. Virtual reality, augmented reality, and robotics applied to digestive operative procedures: from in vivo animal preclinical studies to clinical use

    Science.gov (United States)

    Soler, Luc; Marescaux, Jacques

    2006-04-01

    Technological innovations of the 20 th century provided medicine and surgery with new tools, among which virtual reality and robotics belong to the most revolutionary ones. Our work aims at setting up new techniques for detection, 3D delineation and 4D time follow-up of small abdominal lesions from standard mecial images (CT scsan, MRI). It also aims at developing innovative systems making tumor resection or treatment easier with the use of augmented reality and robotized systems, increasing gesture precision. It also permits a realtime great distance connection between practitioners so they can share a same 3D reconstructed patient and interact on a same patient, virtually before the intervention and for real during the surgical procedure thanks to a telesurgical robot. In preclinical studies, our first results obtained from a micro-CT scanner show that these technologies provide an efficient and precise 3D modeling of anatomical and pathological structures of rats and mice. In clinical studies, our first results show the possibility to improve the therapeutic choice thanks to a better detection and and representation of the patient before performing the surgical gesture. They also show the efficiency of augmented reality that provides virtual transparency of the patient in real time during the operative procedure. In the near future, through the exploitation of these systems, surgeons will program and check on the virtual patient clone an optimal procedure without errors, which will be replayed on the real patient by the robot under surgeon control. This medical dream is today about to become reality.

  9. Changes in operational procedures to improve spaceflight experiments in plant biology in the European Modular Cultivation System

    Science.gov (United States)

    Kiss, John Z.; Aanes, Gjert; Schiefloe, Mona; Coelho, Liz H. F.; Millar, Katherine D. L.; Edelmann, Richard E.

    2014-03-01

    The microgravity environment aboard orbiting spacecraft has provided a unique laboratory to explore topics in basic plant biology as well as applied research on the use of plants in bioregenerative life support systems. Our group has utilized the European Modular Cultivation System (EMCS) aboard the International Space Station (ISS) to study plant growth, development, tropisms, and gene expression in a series of spaceflight experiments. The most current project performed on the ISS was termed Seedling Growth-1 (SG-1) which builds on the previous TROPI (for tropisms) experiments performed in 2006 and 2010. Major technical and operational changes in SG-1 (launched in March 2013) compared to the TROPI experiments include: (1) improvements in lighting conditions within the EMCS to optimize the environment for phototropism studies, (2) the use of infrared illumination to provide high-quality images of the seedlings, (3) modifications in procedures used in flight to improve the focus and overall quality of the images, and (4) changes in the atmospheric conditions in the EMCS incubator. In SG-1, a novel red-light-based phototropism in roots and hypocotyls of seedlings that was noted in TROPI was confirmed and now can be more precisely characterized based on the improvements in procedures. The lessons learned from sequential experiments in the TROPI hardware provide insights to other researchers developing space experiments in plant biology.

  10. "The missing LINX" for gastroesophageal reflux disease: Operative techniques video for the Linx magnetic sphincter augmentation procedure.

    Science.gov (United States)

    Kuckelman, John P; Barron, Morgan R; Martin, Matthew J

    2017-05-01

    In 2012 the FDA approved a magnetic sphincter augmentation (MSA) device (LINX, Torax Medical, Inc) for placement around the lower esophageal sphincter as an alternative approach to fundoplication for gastroesophageal reflux disease (GERD). This is a relatively new procedure and there is not widespread familiarization with the standard indications and techniques of device placement. We present two operative videos to highlight the standard surgical technique and technical points needed for successful LINX placement. First will be placement in a standard indications setting of uncomplicated GERD with no hiatal hernia. Second will be placement with complicated anatomy due to alterations from prior gastric surgery and a hiatal hernia. Our experience has revealed that the LINX device can be placed safely in patients with normal or significantly altered anatomy but requires adherence to several key principles and technical points. This procedure offers a new option that is anatomically and physiologically unique compared to standard fundoplication, and that offers highly effective control of GERD with a less invasive approach. Published by Elsevier Inc.

  11. 标准化作业程序在T物流公司的应用研究%The Applied Research of Standardized Operating Procedures in T Logistics Company

    Institute of Scientific and Technical Information of China (English)

    黄丹莉

    2016-01-01

    通过在T物流企业挂职锻炼,对该企业SOP运用情况进行了详细调研。文中通过对T物流公司运用SOP的经验总结,提出了完善SOP实施的对策。%The use situation of the SOP in T logistics enterprises carried out a detailed investigation through getting practice for the author.This article proposes measures to improve the implementation of SOP by using SOP lessons learned in T logistics enterprises.

  12. 28 CFR 48.16 - Procedure for filing of terms of a renewal or amendment to an existing joint newspaper operating...

    Science.gov (United States)

    2010-07-01

    ... renewal or amendment to an existing joint newspaper operating arrangement. 48.16 Section 48.16 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) NEWSPAPER PRESERVATION ACT § 48.16 Procedure for filing of terms of a renewal or amendment to an existing joint newspaper operating arrangement. Within 30 days after...

  13. Three-dimensional RF SoP technologies: LTCC versus LCP

    KAUST Repository

    Arabi, Eyad A.

    2014-12-18

    The system on package (SoP) is an emerging platform, introduced to provide enhanced functionality, and immense miniaturization through vertically integrated passive components in a multilayer process. This way the package is not a mere holder or cover but is a functional part of the system. The leading multilayer packaging technologies for SoP designs: low temperature co-fired ceramic (LTCC) and liquid crystal polymer (LCP) are compared in this work for the first time. Passive components and filters have been implemented in both technologies to show the advantages of the three-dimensional nature of these technologies. The comparison results show that parallel plate capacitors implemented in the ultra-thin LCP provides the highest capacitance density. For spiral inductors, conversely, LTCC inductors have the highest inductances while LCP inductors offer the highest self-resonant frequencies and the highest quality factors (Q). In a circuit level, simulated and measured results of a bandpass filter at 1.5 GHz show that both LCP and LTCC can provide similar performances with an incredible size reduction for the case of ultra-thin LCP. Also, the thin LCP filter exhibits a large degree of mechanical flexibility which makes this technology suitable for future flexible modules.

  14. 24-GHz LTCC Fractal Antenna Array SoP With Integrated Fresnel Lens

    KAUST Repository

    Ghaffar, Farhan A.

    2012-09-30

    A novel 24-GHz mixed low-temperature co-fired ceramic (LTCC) tape based system-on-package (SoP) is presented, which incorporates a fractal antenna array with an integrated grooved Fresnel lens. The four-element fractal array employs a relatively low dielectric constant substrate (CT707, εr = 6.4), whereas the lens has been realized on a high-dielectric-constant superstrate (CT765, εr = 68.7 ). The two (substrate and superstrate) are integrated through four corner posts to realize the required air gap (focal distance). The fractal array alone provides a measured gain of 8.9 dBi. Simulations predict that integration of this array with the lens increases the gain by 6 dB. Measurements reveal that the design is susceptible to LTCC fabrication tolerances. In addition to high gain, the SoP provides a bandwidth of 8%. The high performance and compact size (24 × 24 × 4.8 mm3 ) of the design makes it highly suitable for emerging wireless applications such as automotive radar front end.

  15. The use of virtual reality and intelligent database systems for procedure planning, visualisation, and real-time component tracking in remote handling operations

    Energy Technology Data Exchange (ETDEWEB)

    Robbins, Edward [JET-EFDA, Culham Science Centre, OX14 3DB, Abingdon (United Kingdom); Oxford Technologies Ltd., 7 Nuffield Way, Abingdon, Oxon, OX14 1RJ (United Kingdom)], E-mail: edward.robbins@oxfordtechnologies.co.uk; Sanders, Stephen; Williams, Adrian [JET-EFDA, Culham Science Centre, OX14 3DB, Abingdon (United Kingdom); Oxford Technologies Ltd., 7 Nuffield Way, Abingdon, Oxon, OX14 1RJ (United Kingdom); Allan, Peter [JET-EFDA, Culham Science Centre, OX14 3DB, Abingdon (United Kingdom); UKAEA/Euratom Fusion Association, Culham Science Centre, Abingdon, Oxfordshire, Oxon OX14 3DB/3EA (United Kingdom)

    2009-06-15

    The organisation of remote handling (RH) operations in fusion environments is increasingly critical as the number of tasks, components and tooling that RH operations teams must deal with inexorably rises. During the recent JET EP1 RH shutdown the existing virtual reality (VR) and procedural database systems proved essential for visualisation and tracking of operations, particularly due to the increasing complexity of remote tasks. A new task planning system for RH operations is in development, and is expected to be ready for use during the next major shutdown, planned for 2009. The system will make use of information available from the remote operations procedures, the RH equipment human-machine interfaces, the on-line RH equipment control systems and also the virtual reality (VR) system to establish a complete database for the location of plant items and RH equipment as RH operations progress. It is intended that the system be used during both preparation and implementation of shutdowns. In the preparations phase the system can be used to validate procedures and overall logistics by allowing an operator to increment through each operation step and to use the VR system to visualise the location and status of all components, manipulators and RH tools. During task development the RH operations engineers can plan and visualise movement of components and tooling to examine handling concepts and establish storage requirements. In the implementation of operations the daily work schedules information will be integrated with the RH operations procedures tracking records to enable the VR system to provide a visual representation of the status of remote operations in real time. Monitoring of the usage history of items will allow estimates of radiation dosage and contaminant exposure to be made. This paper describes the overall aims, structure and use of the system, discusses its application to JET and also considers potential future developments.

  16. Quality and operations of portable X-ray examination procedures in the emergency room: queuing theory at work.

    Science.gov (United States)

    Abujudeh, Hani; Vuong, Bill; Baker, Stephen R

    2005-07-01

    The objective of this study was to evaluate the operation of the portable X-ray machine in relation to examinations ordered by the Emergency Department at the University of Medicine and Dentistry of New Jersey, as well as to identify any bottlenecks hindering the performance of the aforementioned system. To do so, the activity of the portable X-ray was monitored in the period from 8 June 2004 to 24 June 2004, as well as from 6 July 2004 to 12 July 2004, yielding 11 days of data and 116 individual X-ray examinations. During observation times was noted for various checkpoints in the procedure. Using the data gathered, the average input, output, processing times, and variance were calculated. In turn, these values were used to calculate the response times for the Ordering Phase (5.502 min), traveling (2.483 min), Examination Phase (4.453 min), returning (3.855 min), Order Processing Phase (2.962 min), and the Development Phase (3.437 min). These phases were combined for a total of 22.721 min from the time the examination was placed to the time the X-ray films were uploaded to the PACS computer network. Based on these calculations, the Ordering Phase was determined to be the single largest bottleneck in the portable X-ray system. The Examination Phase also represented the second largest bottleneck for a combined total of 44% of the total response time.

  17. Integrating the SOP[superscript 2] Model into the Flipped Classroom to Foster Cognitive Presence and Learning Achievements

    Science.gov (United States)

    Chen, Hsiu-Ling; Chang, Chiung-Yun

    2017-01-01

    This study explored student teachers' cognitive presence and learning achievements by integrating the SOP[superscript 2] Model in which self-study (S), online group discussion (O) and double-stage presentations (P[superscript 2]) were implemented in the flipped classroom. The research was conducted at a university in Taiwan with 31 student…

  18. Safety training and safe operating procedures written for PBFA (Particle Beam Fusion Accelerator) II and applicable to other pulsed power facilities

    Energy Technology Data Exchange (ETDEWEB)

    Donovan, G.L.; Goldstein, S.A.

    1986-12-01

    To ensure that work in advancing pulsed power technology is performed with an acceptably low risk, pulsed power research facilities at Sandia National Laboratories must satisfy general safety guidelines established by the Department of Energy, policies and formats of the Environment, Safety, and Health (ES and H) Department, and detailed procedures formulated by the Pulsed Power Sciences Directorate. The approach to safety training and to writing safe operating procedures, and the procedures presented here are specific to the Particle Beam Fusion Accelerator II (PBFA II) Facility but are applicable as guidelines to other research and development facilities which have similar hazards.

  19. [Conditions for the survival of combat casualties in overseas operations: procedure and experience from the Afghan out-of-hospital theater].

    Science.gov (United States)

    Palmier, Bruno

    2012-01-01

    Recent conflicts have led the French Army Health Service to specify the setting condition for the survival of combat casualties in overseas operations. The majority of them are victims of explosion injuries, and an early and effective control of bleeding is the primary means of improving survival. A procedure called "Combat Rescue" is taught. This chronological procedure favours external haemostasis and led to specific equipment, in particular a tourniquet and a haemostatic bandage of high efficiency. It is applied in recent years on the Afghan out-of-hospital theatre. A very front medical presence, which is systematic during evacuations, is a feature of the French Army Health Service operations support.

  20. Operating Procedures and the Expectations Theory of the Term Structure of Interest Rates: A Note on the New Zealand Experience from 1989 to 2008

    OpenAIRE

    Alfred Guender; Allan G.J. Wu

    2010-01-01

    The operating procedure of a central bank influences in no small measure whether the behavior of interest rates is consistent with the expectations hypothesis. In New Zealand, the predictive content of the term spread improves markedly in the wake of the switch from a quantity-based to a price-based operating procedure in March 1999. The Official Cash Rate system has made it easier for market participants to understand the day-to-day conduct of monetary policy. As a result, market interest ra...

  1. Salmonella Disrupts Host Endocytic Trafficking by SopD2-Mediated Inhibition of Rab7

    Directory of Open Access Journals (Sweden)

    Vanessa M. D’Costa

    2015-09-01

    Full Text Available Intracellular bacterial pathogens of a diverse nature share the ability to evade host immunity by impairing trafficking of endocytic cargo to lysosomes for degradation, a process that is poorly understood. Here, we show that the Salmonella enterica type 3 secreted effector SopD2 mediates this process by binding the host regulatory GTPase Rab7 and inhibiting its nucleotide exchange. Consequently, this limits Rab7 interaction with its dynein- and kinesin-binding effectors RILP and FYCO1 and thereby disrupts host-driven regulation of microtubule motors. Our study identifies a bacterial effector capable of directly binding and thereby modulating Rab7 activity and a mechanism of endocytic trafficking disruption that may provide insight into the pathogenesis of other bacteria. Additionally, we provide a powerful tool for the study of Rab7 function, and a potential therapeutic target.

  2. Coastal Observations of Weather Features in Senegal during the AMMA SOP-3 Period

    Science.gov (United States)

    Jenkins, G.; Kucera, P.; Joseph, E.; Fuentes, J.; Gaye, A.; Gerlach, J.; Roux, F.; Viltard, N.; Papazzoni, M.; Protat, A.; Bouniol, D.; Reynolds, A.; Arnault, J.; Badiane, D.; Kebe, F.; Camara, M.; Sall, S.

    2009-01-01

    During 15 August through 30 September 2006, ground and aircraft measurements were obtained from a multi-national group of students and scientists in Senegal. Key measurements were aimed at investigating and understanding precipitation processes, thermodynamic and dynamic environmental conditions, cloud, aerosol and microphysical processes and spaceborne sensors (TRMM, CloudSat/Calipso) validation. Ground and aircraft instruments include: ground based polarimetric radar, disdrometer measurements, a course and a high-density rain gauge network, surface chemical measurements, a 10 m flux tower, broadband IR, solar and microwave measurements, rawinsonde and radiosonde measurements, FA-20 dropsonde, in situ microphysics and cloud radar measurements. Highlights during SOP3 include ground and aircraft measurements of squall lines, African Easterly Waves (AEWs), Saharan Air Layer advances into Senegal, and aircraft measurements of AEWs -- including the perturbation that became Hurricane Isaac.

  3. Vertical profiles of heating derived from IR-based precipitation estimates during FGGE SOP-1

    Science.gov (United States)

    Robertson, Franklin R.; Vincent, Dayton G.

    1988-01-01

    This paper examines a technique for retrieving from geostationary IR data the vertical profiles of heating and cooling due to moist diabatic processes. First, GOES IR imagery is used to estimate precipitation fields which are independent of fields inferred from residuals in heat budget analysis based on the FGGE level III-b data. Vertical distributions of the associated heating are then obtained using thermodynamic data from the level III-b analysis, one-dimensional cloud models, and the satellite-estimated precipitation. The technique was applied to infer heating in the South Pacific convergence zone during a portion of FGEE SOP-1, and the results were compared with heat-budget calculations made using the ECMWF analyses.

  4. 系统单芯片之外的另一种选择--SOP

    Institute of Scientific and Technical Information of China (English)

    陈怡然

    2004-01-01

    @@ 当今主流半导体有些技术上的限制,系统单芯片的设计并不适用于所有的系统,为了要达到高度集成的目的,同时保持系统应有的效能及可接受的成本,System-on-Package(SOP)被提出来,成为系统单芯片之外的另一种选择.本文将简介SOP的背景、技术,且分析SOP与其它集成技术的异同,及其发展概况.

  5. Investigation of a convection event using multisensor observations during HyMeX SOP1

    Science.gov (United States)

    Roberto, Nicoletta; Adirosi, Elisa; Casella, Daniele; Dietrich, Stefano; Panegrossi, Giulia; Petracca, Marco; Sanò, Paolo; Gatlin, Patrick; Baldini, Luca

    2014-05-01

    A multisensor analysis of the convective precipitation event occurred over Rome during the IOP13 (October 15th, 2012) of the HyMeX (Hydrological cycle in the Mediterranean eXperiment) Special Observation Period (SOP) 1 is presented. Thanks to the cooperation among Italian meteorological services and scientific community and a specific agreement with NASA-GSFC, different types of devices for meteorological measurements were made available during the HyMeX SOP.1. For investigating this event, used are the 3-D lightning data provided by the LINET, the CNR ISAC dual-pol C-band radar (Polar 55C), located in Rome, the Drop Size Distributions (DSD) collected by the 2D Video Disdrometer (2DVD) and the collocated Micro Rain Radar (MRR) installed at the Radio Meteorology Lab. of "Sapienza" University of Rome, located 14 km from the Polar 55C radar. The relation between microphysical structure and electrical activity during the convective phase of the event was investigated using LINET lightning data and Polar 55C (working both in PPI and RHI scanning mode) observations. Location of regions of high horizontal reflectivity (Zh) values ( > 50 dBz), indicating convective precipitation, were found to be associated to a high number of LINET strokes. In addition, an hydrometeor classification scheme applied to the Polar 55C scans was used to detect graupel and to identify a relation between number of LINET strokes and integrated IWC of graupel along the event. Properties of DSDs measured by the 2DVD and vertical DSD profiles estimated by MRR and their relation with the lighting activity registered by LINET were investigated with specific focus on the transition from convective to stratiform regimes. A good agreement was found between convection detected by these instruments and the number of strokes detected by LINET.

  6. A Multisensor Investigation of Convection During HyMeX SOP1 IOP13

    Science.gov (United States)

    Roberto, N.; Adirosi, E.; Baldini, L.; Casella, D.; Dietrich, S.; Panegrossi, G.; Petracca, M.; Sano, P.; Gatlin, P.

    2014-01-01

    A multisensor analysis of the convective precipitation event occurred over Rome during the IOP13 (October 15th, 2012) of the HyMeX (Hydrological cycle in the Mediterranean eXperiment) Special Observation Period (SOP) 1 is presented. Thanks to the cooperation among Italian meteorological services and scientific community and a specific agreement with NASA-GSFC, different types of devices for meteorological measurements were made available during the HyMeX SOP.1. For investigating this event, used are the 3-D lightning data provided by the LINET, the CNR ISAC dual-pol C-band radar (Polar 55C), located in Rome, the Drop Size Distributions (DSD) collected by the 2D Video Disdrometer (2DVD) and the collocated Micro Rain Radar (MRR) installed at the Radio Meteorology Lab. of "Sapienza" University of Rome, located 14 km from the Polar 55C radar. The relation between microphysical structure and electrical activity during the convective phase of the event was investigated using LINET lightning data and Polar 55C (working both in PPI and RHI scanning mode) observations. Location of regions of high horizontal reflectivity (Zh) values ( > 50 dBz), indicating convective precipitation, were found to be associated to a high number of LINET strokes. In addition, an hydrometeor classification scheme applied to the Polar 55C scans was used to detect graupel and to identify a relation between number of LINET strokes and integrated IWC of graupel along the event. Properties of DSDs measured by the 2DVD and vertical DSD profiles estimated by MRR and their relation with the lighting activity registered by LINET were investigated with specific focus on the transition from convective to stratiform regimes. A good agreement was found between convection detected by these instruments and the number of strokes detected by LINET.

  7. An improved automated procedure for informal and temporary dwellings detection and enumeration, using mathematical morphology operators on VHR satellite data

    Science.gov (United States)

    Jenerowicz, Małgorzata; Kemper, Thomas

    2016-10-01

    Every year thousands of people are displaced by conflicts or natural disasters and often gather in large camps. Knowing how many people have been gathered is crucial for an efficient relief operation. However, it is often difficult to collect exact information on the total number of the population. This paper presents the improved morphological methodology for the estimation of dwellings structures located in several Internally Displaced Persons (IDPs) Camps, based on Very High Resolution (VHR) multispectral satellite imagery with pixel sizes of 1 meter or less including GeoEye-1, WorldView-2, QuickBird-2, Ikonos-2, Pléiades-A and Pléiades-B. The main topic of this paper is the approach enhancement with selection of feature extraction algorithm, the improvement and automation of pre-processing and results verification. For the informal and temporary dwellings extraction purpose the high quality of data has to be ensured. The pre-processing has been extended by including the input data hierarchy level assignment and data fusion method selection and evaluation. The feature extraction algorithm follows the procedure presented in Jenerowicz, M., Kemper, T., 2011. Optical data are analysed in a cyclic approach comprising image segmentation, geometrical, textural and spectral class modeling aiming at camp area identification. The successive steps of morphological processing have been combined in a one stand-alone application for automatic dwellings detection and enumeration. Actively implemented, these approaches can provide a reliable and consistent results, independent of the imaging satellite type and different study sites location, providing decision support in emergency response for the humanitarian community like United Nations, European Union and Non-Governmental relief organizations.

  8. Benefits to blood banks of a sales and operations planning process.

    Science.gov (United States)

    Keal, Donald A; Hebert, Phil

    2010-12-01

    A formal sales and operations planning (S&OP) process is a decision making and communication process that balances supply and demand while integrating all business operational components with customer-focused business plans that links high level strategic plans to day-to-day operations. Furthermore, S&OP can assist in managing change across the organization as it provides the opportunity to be proactive in the face of problems and opportunities while establishing a plan for everyone to follow. Some of the key outcomes from a robust S&OP process in blood banking would include: higher customer satisfaction (donors and health care providers), balanced inventory across product lines and customers, more stable production rates and higher productivity, more cooperation across the entire operation, and timely updates to the business plan resulting in better forecasting and fewer surprises that negatively impact the bottom line.

  9. A Guide for Developing Standard Operating Job Procedures for the Activated Sludge - Aeration & Sedimentation Process Wastewater Treatment Facility. SOJP No. 5.

    Science.gov (United States)

    Mason, George J.

    This guide for developing standard operating job procedures for wastewater treatment facilities is devoted to the activated sludge aeration and sedimentation process. This process is for conversion of nonsettleable and nonfloatable materials in wastewater to settleable, floculated biological groups and separation of the settleable solids from the…

  10. Diagnosis and dosimetry of exposure to sulfur mustard: Development of a standard operating procedure for mass spectrometric analysis of haemoglobin adducts - Exploratory research on albumin and keratin adducts

    NARCIS (Netherlands)

    Noort, D.; Fidder, A.; Hulst, A.G.; Jong, L.P.A. de; Benschop, H.P.

    2000-01-01

    Experiments were carried out to develop a standard operating procedure for analysis of sulfur mustard adducts to the N-terminal valine in haemoglobin and to explore adduct formation with albumin and keratin. In the first approach, gas chromatography-negative chemical ionization/mass spectrometry (GC

  11. General ultrasound screening reduces the rate of first operative procedures for developmental dysplasia of the hip: a case-control study.

    Science.gov (United States)

    von Kries, Rüdiger; Ihme, Nicola; Altenhofen, Lutz; Niethard, Fritz Uwe; Krauspe, Rüdiger; Rückinger, Simon

    2012-02-01

    To assess the effectiveness of general ultrasound screening to prevent first operative procedures of the hip. We conducted a case-control study in a population in which general ultrasound screening supplementing clinical screening is recommended and offered free of charge for all children. Participation in ultrasound screening before week 7 as recommended in Germany was the exposure of interest. Case ascertainment was based on active surveillance in orthopedic hospitals. The case definition was: first operative procedure for developmental dysplasia of the hip (closed reduction, open reduction, or osteotomy) in children >9 weeks old and dysplasia of the hip (n = 446) were compared with 1173 control subjects for ultrasound screening. Effectiveness of ultrasound screening to prevent first operative procedures for developmental dysplasia of the hip was estimated as 52% (95% CI, 32-67). Effectiveness did not vary substantially for closed and open reductions and osteotomy. General ultrasound screening reduces the rate of operative procedures for developmental dysplasia of the hip; the impact on developmental dysplasia of the hip. Treatment rates and avascular necrosis need further assessment to balance the benefit against potential overtreatment and adverse effects. Copyright © 2012 Mosby, Inc. All rights reserved.

  12. A Guide for Developing Standard Operating Job Procedures for the Activated Sludge - Aeration & Sedimentation Process Wastewater Treatment Facility. SOJP No. 5.

    Science.gov (United States)

    Mason, George J.

    This guide for developing standard operating job procedures for wastewater treatment facilities is devoted to the activated sludge aeration and sedimentation process. This process is for conversion of nonsettleable and nonfloatable materials in wastewater to settleable, floculated biological groups and separation of the settleable solids from the…

  13. Prediction of patient-specific post-operative outcomes of TAVI procedure: The impact of the positioning strategy on valve performance.

    Science.gov (United States)

    Morganti, S; Brambilla, N; Petronio, A S; Reali, A; Bedogni, F; Auricchio, F

    2016-08-16

    Prosthesis positioning in transcatheter aortic valve implantation procedures represents a crucial aspect for procedure success as demonstrated by many recent studies on this topic. Possible complications, device performance, and, consequently, also long-term durability are highly affected by the adopted prosthesis placement strategy. In the present work, we develop a computational finite element model able to predict device-specific and patient-specific replacement procedure outcomes, which may help medical operators to plan and choose the optimal implantation strategy. We focus in particular on the effects of prosthesis implantation depth and release angle. We start from a real clinical case undergoing Corevalve self-expanding device implantation. Our study confirms the crucial role of positioning in determining valve anchoring, replacement failure due to intra or para-valvular regurgitation, and post-operative device deformation.

  14. Atlantic Tropical Cyclogenetic Processes During SOP-3 NAMMA in the GEOS-5 Global Data Assimilation and Forecast System

    Science.gov (United States)

    Reale, Oreste; Lau, William K.; Kim, Kyu-Myong; Brin, Eugenia

    2009-01-01

    This article investigates the role of the Saharan air layer (SAL) in tropical cyclogenetic processes associated with a nondeveloping and a developing African easterly wave observed during the Special Observation Period (SOP-3) phase of the 2006 NASA African. Monsoon Multidisciplinary Analyses (NAMMA). The two waves are chosen because they both interact heavily with Saharan air. A glottal data assimilation and forecast system, the NASA Goddard Earth Observing System. version 5 (GEOS-5), is being run to produce a set of high-9 uality global analyses, inclusive of all observations used operationally but with additional satellite information. In particular, following previous works by the same authors, the duality-controlled data from the Atmospheric Infrared Sounder (AIRS) used to produce these analyses have a better coverage than the one adopted by operational centers. From these improved analyses, two sets of 31 five-day high-resolution forecasts, at horizontal resolutions of both half and quarter degrees, are produced. Results indicate that very steep moisture gradients are associated with the SAL in forecasts and analyses, even at great distances from their source over the Sahara. In addition, a thermal dipole in the vertiieat (warm above, cool below) is present in the nondeveloping case. The Moderate Resolution Imaging Spoctroradiometer (MODIS) aboard NASA's Terra and Aqua satellites shows that aerosol optical thickness, indicative of more dust as opposed to other factors, is higher in the nondeveloping case. Altogether, results suggest that the radiative effect of dust may play some role in producing a thermal structure less favorable to cyclogenesis. Results also indicate that only global horizontal resolutions on the order of 20-30 km can capture the large-scale transport and the tine thermal structure of the SAL, inclusive of the sharp moisture gradients, reproducing the effect of tropical cyclone suppression that has been hypothesized by previous authors

  15. Establishment, Performance and Management of SOP in GLP Laboratory%GLP机构中SOP的制定、执行与管理

    Institute of Scientific and Technical Information of China (English)

    张呈菊; 马璟; 李旻; 葛元圆; 职阳阳; 徐维露; 孙涟

    2015-01-01

    目的:描述GLP机构内SOP的制定、执行和管理。方法:介绍GLP机构内SOP的种类和模板、书写、审阅、审批、生效前培训、分发、使用、回收,保存和销毁等过程。结果与结论:通过上述SOP的系列管理过程,获得SOP的良好管理。%Objective:To describe the establishment, performance and management of SOP in GLP laboratory. Methods: Those terms such as categories, templates, writing, review, approval, training before it becomes effective, distribution, usage, recycling, preservation and destruction of the SOP in the GLP laboratory were introduced. Results and Conclusion: Through the series of SOP management, good SOP management was achieved.

  16. Comparison between local anaesthesia with remifentanil and total intravenous anaesthesia for operative hysteroscopic procedures in day surgery

    DEFF Research Database (Denmark)

    Majholm, B; Bartholdy, J; Clausen, H V;

    2012-01-01

    BACKGROUND: /st>This study aimed at comparing total i.v. anaesthesia (TIVA) with monitored anaesthesia care (MAC) during day-surgery operative hysteroscopy regarding: operation time, time to mobilization and discharge, and patient satisfaction. METHODS: /st>Ninety-one healthy women were randomized.......003). CONCLUSIONS: /st>Paracervical local anaesthesia combined with remifentanil is suitable for operative hysteroscopy in day surgery....

  17. Initial Investigations of Controller Tools and Procedures for Schedule-Based Arrival Operations with Mixed Flight-Deck Interval Management Equipage

    Science.gov (United States)

    Callantine, Todd J.; Cabrall, Christopher; Kupfer, Michael; Omar, Faisal G.; Prevot, Thomas

    2012-01-01

    NASA?s Air Traffic Management Demonstration-1 (ATD-1) is a multi-year effort to demonstrate high-throughput, fuel-efficient arrivals at a major U.S. airport using NASA-developed scheduling automation, controller decision-support tools, and ADS-B-enabled Flight-Deck Interval Management (FIM) avionics. First-year accomplishments include the development of a concept of operations for managing scheduled arrivals flying Optimized Profile Descents with equipped aircraft conducting FIM operations, and the integration of laboratory prototypes of the core ATD-1 technologies. Following each integration phase, a human-in-the-loop simulation was conducted to evaluate and refine controller tools, procedures, and clearance phraseology. From a ground-side perspective, the results indicate the concept is viable and the operations are safe and acceptable. Additional training is required for smooth operations that yield notable benefits, particularly in the areas of FIM operations and clearance phraseology.

  18. U.S. Geological Survey Noble Gas Laboratory’s standard operating procedures for the measurement of dissolved gas in water samples

    Science.gov (United States)

    Hunt, Andrew G.

    2015-08-12

    This report addresses the standard operating procedures used by the U.S. Geological Survey’s Noble Gas Laboratory in Denver, Colorado, U.S.A., for the measurement of dissolved gases (methane, nitrogen, oxygen, and carbon dioxide) and noble gas isotopes (helium-3, helium-4, neon-20, neon-21, neon-22, argon-36, argon-38, argon-40, kryton-84, krypton-86, xenon-103, and xenon-132) dissolved in water. A synopsis of the instrumentation used, procedures followed, calibration practices, standards used, and a quality assurance and quality control program is presented. The report outlines the day-to-day operation of the Residual Gas Analyzer Model 200, Mass Analyzer Products Model 215–50, and ultralow vacuum extraction line along with the sample handling procedures, noble gas extraction and purification, instrument measurement procedures, instrumental data acquisition, and calculations for the conversion of raw data from the mass spectrometer into noble gas concentrations per unit mass of water analyzed. Techniques for the preparation of artificial dissolved gas standards are detailed and coupled to a quality assurance and quality control program to present the accuracy of the procedures used in the laboratory.

  19. Tableau-based decision procedure for the multi-agent epistemic logic with all coalitional operators for common and distributed knowledge

    CERN Document Server

    Ajspur, Mai; Shkatov, Dmitry

    2012-01-01

    We develop a conceptually clear, intuitive, and feasible decision procedure for testing satisfi?ability in the full multi-agent epistemic logic CMAEL(CD) with operators for common and distributed knowledge for all coalitions of agents mentioned in the language. To that end, we introduce Hintikka structures for CMAEL(CD) and prove that satisfiability in such structures is equivalent to satis?fiability in standard models. Using that result, we design an incremental tableau-building procedure that eventually constructs a satisfying Hintikka structure for every satisfi?able input set of formulae of CMAEL(CD) and closes for every unsatisfi?able input set of formulae.

  20. Structural basis for the reversible activation of a Rho protein by the bacterial toxin SopE

    OpenAIRE

    Buchwald, Gretel; Friebel, Andrea; Galán, Jorge E.; Hardt, Wolf-Dietrich; Wittinghofer, Alfred; Scheffzek, Klaus

    2002-01-01

    The bacterial enteropathogen Salmonella typhimurium employs a type III secretion system to inject bacterial toxins into the host cell cytosol. These toxins transiently activate Rho family GTP-binding protein-dependent signaling cascades to induce cytoskeletal rearrangements. One of these translocated Salmonella toxins, SopE, can activate Cdc42 in a Dbl-like fashion despite its lack of sequence similarity to Dbl-like proteins, the Rho-specific eukaryotic guanine nucleotide exchange factors. To...

  1. Allied Medical Publication AMedP-7.6(A), Commander’s Guide to Medical Operations in Support of CBRN Defensive Operations: Study Draft 1

    Science.gov (United States)

    2015-07-01

    degradation of operational capability due to use of physical protection. While assuming a protected posture (Mission Oriented Protective Posture ... hygiene measures (e.g., limits on physical contact) Guidance on issues requiring operational-level coordination, advice, assessment SOPs for movement...Information and Coordination System MOPP Mission Oriented Protective Posture MRIIT Medical Radiation Incident Investigation Team MTF Medical Treatment

  2. Corporate governance structure which is based in the S&OP process: Case study in la Brazilian cosmetic company

    Directory of Open Access Journals (Sweden)

    Ximena Rojas

    2014-03-01

    Full Text Available (Received: 2014/01/31 - Accepted: 2014/03/25This article is about the generation of a corporate governance structure which is based in the process S&OP for a Brazilian cosmetic industry. The increasing emphasis on business development guided by attention to the requirements and demands of customers, cause nowadays, that the organizations of the commercial sectors work in the creation of a competitive differential. The collaborative business management strategy S&OP is looking for the attention of people who are interested in the improvement of their skills; in order to achieve this differential. With the case study methodology, the objectives are to get knowledge, identify, and analyze the characteristics of the company using analysis tools like SWOT, process analysis, value chain. All with the purpose to get a robust management tool that fits with the requirements and demands of the organization. The analyzed results showed that the principles of collaboration and internal communication were the pillars necessary against any attempt of business development. This supports the proposal of a management structure based on the five step S&OP process. As a complement to this study a methodology CPFR was identified as the platform for an integrated work with the rest of the companies of the supply chain.

  3. The Salmonella Effector Protein SopA Modulates Innate Immune Responses by Targeting TRIM E3 Ligase Family Members.

    Directory of Open Access Journals (Sweden)

    Jana Kamanova

    2016-04-01

    Full Text Available Salmonella Typhimurium stimulates inflammatory responses in the intestinal epithelium, which are essential for its ability to replicate within the intestinal tract. Stimulation of these responses is strictly dependent on the activity of a type III secretion system encoded within its pathogenicity island 1, which through the delivery of effector proteins, triggers signaling pathways leading to inflammation. One of these effectors is SopA, a HECT-type E3 ligase, which is required for the efficient stimulation of inflammation in an animal model of Salmonella Typhimurium infection. We show here that SopA contributes to the stimulation of innate immune responses by targeting two host E3 ubiquitin ligases, TRIM56 and TRIM65. We also found that TRIM65 interacts with the innate immune receptor MDA5 enhancing its ability to stimulate interferon-β signaling. Therefore, by targeting TRIM56 and TRIM65, SopA can stimulate signaling through two innate immune receptors, RIG-I and MDA5. These findings describe a Salmonella mechanism to modulate inflammatory responses by directly targeting innate immune signaling mechanisms.

  4. Content Analysis of Vomit and Diarrhea Cleanup Procedures To Prevent Norovirus Infections in Retail and Food Service Operations.

    Science.gov (United States)

    Chao, Morgan G; Dubé, Anne-Julie; Leone, Cortney M; Moore, Christina M; Fraser, Angela M

    2016-11-01

    Human noroviruses are the leading cause of foodborne disease in the United States, sickening 19 to 21 million Americans each year. Vomit and diarrhea are both highly concentrated sources of norovirus particles. For this reason, establishing appropriate cleanup procedures for these two substances is critical. Food service establishments in states that have adopted the 2009 or 2013 U.S. Food and Drug Administration Food Code are required to have a program detailing specific cleanup procedures. The aim of our study was to determine the alignment of existing vomit and diarrhea cleanup procedures with the 11 elements recommended in Annex 3 of the 2011 Supplement to the 2009 Food Code and to determine their readability and clarity of presentation. In July 2015, we located vomit and diarrhea cleanup procedures by asking Norovirus Collaborative for Outreach, Research, and Education stakeholders for procedures used by their constituency groups and by conducting a Google Advanced Search of the World Wide Web. We performed content analysis to determine alignment with the recommendations in Annex 3. Readability and clarity of presentation were also assessed. A total of 38 artifacts were analyzed. The mean alignment score was 7.0 ± 1.7 of 11 points; the mean clarity score was 6.7 ± 2.5 of 17 points. Only nine artifacts were classified as high clarity, high alignment. Vomit and diarrhea cleanup procedures should align with Annex 3 in the Food Code and should, as well, be clearly presented; yet, none of the artifacts completely met both conditions. To reduce the spread of norovirus infections in food service establishments, editable guidelines are needed that are aligned with Annex 3 and are clearly written, into which authors could insert their facility-specific information.

  5. 核电厂运行规程标准化开发的研究%Research on Operating Procedures Standardized Development for Nuclear Power Plants

    Institute of Scientific and Technical Information of China (English)

    施锦; 薛山虎

    2016-01-01

    While operating procedures documentations are complex and are very important to safe opera⁃tion of nuclear power plants, the development of operating procedures standardizations are required to en⁃sure the correctness and standardization of procedures� Based on the framework analysis of operating pro⁃cedures for CAP series advanced passive plants, the functional requirements of procedures standardization development are analyzed� Through programming and code implementation, some tools for procedures standardized development are designed and established, as well as a software platform� The operating pro⁃cedures developers are able to establish standardized operating procedures through the platform� Meanwhile the important technical contents are informationized� The specific practices show that this platform sup⁃ports operating procedure standardization efficiently, and meets the regulatory requirements for operating limits and conditions� It also benefits the human errors reduction for operators from the start of operating procedures design, which is meaningful to enhance the operational safety of nuclear power plants.%由于运行规程文件体系的复杂性、运行规程对核电厂安全运行的重要性,为了充分保证运行规程的正确性和规范性,实现核电厂运行规程的标准化开发是十分必要的。本文基于规程体系和内容结构的分析,对CAP系列核电厂运行规程标准化开发的需求进行了分析,通过程序设计和代码实现开发了规程标准化开发工具并建立了规程标准化开发平台。规程开发人员能够通过平台应用使开发出的规程文件标准化、规程重要技术内容信息化,并在后台实现数据管理。实践表明,运行规程标准化开发平台能够有效提高规程的质量和开发效率,满足核安全法规对运行限值和条件的跟踪、配置管理要求,能够从设计源头降低主控室操纵员出现人因

  6. DOE Field Operations Program EV and HEV Testing

    Energy Technology Data Exchange (ETDEWEB)

    Francfort, James Edward; Slezak, L. A.

    2001-10-01

    The United States Department of Energy’s (DOE) Field Operations Program tests advanced technology vehicles (ATVs) and disseminates the testing results to provide fleet managers and other potential ATV users with accurate and unbiased information on vehicle performance. The ATVs (including electric, hybrid, and other alternative fuel vehicles) are tested using one or more methods - Baseline Performance Testing (EVAmerica and Pomona Loop), Accelerated Reliability Testing, and Fleet Testing. The Program (http://ev.inel.gov/sop) and its nine industry testing partners have tested over 30 full-size electric vehicle (EV) models and they have accumulated over 4 million miles of EV testing experience since 1994. In conjunction with several original equipment manufacturers, the Program has developed testing procedures for the new classes of hybrid, urban, and neighborhood EVs. The testing of these vehicles started during 2001. The EVS 18 presentation will include (1) EV and hybrid electric vehicle (HEV) test results, (2) operating experience with and performance trends of various EV and HEV models, and (3) experience with operating hydrogen-fueled vehicles. Data presented for EVs will include vehicle efficiency (km/kWh), average distance driven per charge, and range testing results. The HEV data will include operating considerations, fuel use rates, and range testing results.

  7. An operational procedure for precipitable and cloud liquid water estimate in non-raining conditions over sea Study on the assessment of the nonlinear physical inversion algorithm

    CERN Document Server

    Nativi, S; Mazzetti, P

    2004-01-01

    In a previous work, an operative procedure to estimate precipitable and liquid water in non-raining conditions over sea was developed and assessed. The procedure is based on a fast non-linear physical inversion scheme and a forward model; it is valid for most of satellite microwave radiometers and it also estimates water effective profiles. This paper presents two improvements of the procedure: first, a refinement to provide modularity of the software components and portability across different computation system architectures; second, the adoption of the CERN MINUIT minimisation package, which addresses the problem of global minimisation but is computationally more demanding. Together with the increased computational performance that allowed to impose stricter requirements on the quality of fit, these refinements improved fitting precision and reliability, and allowed to relax the requirements on the initial guesses for the model parameters. The re-analysis of the same data-set considered in the previous pap...

  8. Classifying breast cancer surgery: a novel, complexity-based system for oncological, oncoplastic and reconstructive procedures, and proof of principle by analysis of 1225 operations in 1166 patients.

    Science.gov (United States)

    Hoffmann, Jürgen; Wallwiener, Diethelm

    2009-04-08

    One of the basic prerequisites for generating evidence-based data is the availability of classification systems. Attempts to date to classify breast cancer operations have focussed on specific problems, e.g. the avoidance of secondary corrective surgery for surgical defects, rather than taking a generic approach. Starting from an existing, simpler empirical scheme based on the complexity of breast surgical procedures, which was used in-house primarily in operative report-writing, a novel classification of ablative and breast-conserving procedures initially needed to be developed and elaborated systematically. To obtain proof of principle, a prospectively planned analysis of patient records for all major breast cancer-related operations performed at our breast centre in 2005 and 2006 was conducted using the new classification. Data were analysed using basic descriptive statistics such as frequency tables. A novel two-type, six-tier classification system comprising 12 main categories, 13 subcategories and 39 sub-subcategories of oncological, oncoplastic and reconstructive breast cancer-related surgery was successfully developed. Our system permitted unequivocal classification, without exception, of all 1225 procedures performed in 1166 breast cancer patients in 2005 and 2006. Breast cancer-related surgical procedures can be generically classified according to their surgical complexity. Analysis of all major procedures performed at our breast centre during the study period provides proof of principle for this novel classification system. We envisage various applications for this classification, including uses in randomised clinical trials, guideline development, specialist surgical training, continuing professional development as well as quality of care and public health research.

  9. Compliance of REE's operational procedure 12.3 regarding fault ride-through capability. The experience of a multi-technology owner

    Energy Technology Data Exchange (ETDEWEB)

    Ruiz Guillen, J.; Giraut Ruso, E.; Quinonez-Varela, G.; Navarrete Pablo-Romero, A.; Rebollo Rico, I.; Hernandez Fernandez de la Pradilla, T. [Acciona Energia, Sarriguren (Spain); Comench, M.P.; Garcia-Gracia, M. [Zaragoza Univ. (Spain). CIRCE

    2009-07-01

    The installed wind power capacity in Spain has rapidly increased over the last years, and consequently, a number of issues associated to the security and reliability of the power system have been prompted. A critical aspect is the fault ride-through capability of wind turbine generators. In 2006, the Spanish TSO published a new Operational Procedure which governs this capability for wind power plants, either new or existing, and was enforced in 2007. This paper describes the requirements that the wind power plants have to fulfil to comply with the Operational Procedure, the multiple technologies that Acciona Energia had to retrofit and the theoretical solutions that were analysed during this process. Also, simulations and field tests are discussed, together with a discussion on the current situation of solutions for old wind power plants, and the lessons learned throughout the retrofit process. (orig.)

  10. Applications for a hybrid operating room in thoracic surgery: from multidisciplinary procedures to ­­image-guided video-assisted thoracoscopic surgery

    Science.gov (United States)

    Terra, Ricardo Mingarini; Andrade, Juliano Ribeiro; Mariani, Alessandro Wasum; Garcia, Rodrigo Gobbo; Succi, Jose Ernesto; Soares, Andrey; Zimmer, Paulo Marcelo

    2016-01-01

    ABSTRACT The concept of a hybrid operating room represents the union of a high-complexity surgical apparatus with state-of-the-art radiological tools (ultrasound, CT, fluoroscopy, or magnetic resonance imaging), in order to perform highly effective, minimally invasive procedures. Although the use of a hybrid operating room is well established in specialties such as neurosurgery and cardiovascular surgery, it has rarely been explored in thoracic surgery. Our objective was to discuss the possible applications of this technology in thoracic surgery, through the reporting of three cases. PMID:27812640

  11. Peri-operative data on the nuss procedure in children with pectus excavatum: independent survey of the first 20 years' data

    OpenAIRE

    Athanasiou Thanos; Protopapas Aristotle D

    2008-01-01

    Abstract Objective To review the literature and assess the cumulative data on the Nuss operation in children on its twenty years' anniversary: The Nuss procedure corrects the pectus excavatum by minimal access semi-permanent insertion of metal bars in order to reduce the deformity and refashion the contour of the growing thorax. The advantage over previous techniques is avoidance of osteochondrotomies and thence allowance for normal growth of the thorax. Study design PubMed search was perform...

  12. A modularized framework for sales and operations planning with focus on process industries

    Directory of Open Access Journals (Sweden)

    Sayeh Noroozi

    2016-01-01

    Full Text Available This paper suggests a modularized sales and operations planning (S&OP framework, consisting of content and process. The framework’s content is based on a typology of decoupling points in which the effect of decoupling points on the decision variables in S&OP is studied. The framework’s process takes a step back and addresses the need for a more elaborate design to precede the operational use of S&OP content for different production contexts. The framework supports both process industries (PIs and discrete manufacturing industries (DIs, and recognizes their specific requirements and reflects them in their S&OP. The differentiating characteristics of PIs and DIs are emphasized through three different decoupling points, namely: discretization decoupling point, control mode decoupling point, and customer order decoupling point. The suggested framework aims to fill the gap in the literature regarding the lack of aggregate planning processes that match the PIs’ specific requirements by reflecting the differentiating characteristics of PIs in S&OP.

  13. Evaluation of glass model precipitation forecasts for North America during SOP-1

    Science.gov (United States)

    Atlas, R.; Firestone, J.

    1984-01-01

    A study has been made of the accuracy of the GLAS fourth order forecast model's precipitation forecasts over North America during the first Special Observing Period (SOP-1) of FGGE and of the impact of the FGGE special observing systems on these forecasts. Fourteen 120 h predictions were generated using the coarse 4 deg latitude by 5 deg longitude version of the GLAS model from both the FGGE and NOSAT assimilation cycles. These forecasts were then verified against a detailed set of precipitation observations. Separate verifications were performed for precipitation accumulations or = .01 in., or = .1 in., and or = 1 in. occuring in 6, 12 and 24 time periods. In addition, three different methods of verification were applied. In the first method, model precipitation forecasts are verified against the greatest precipitation amount observed within a 4 deg latitude by 5 deg longitude gridbox centered on each gridpoint. For the prediction at a gridpoint to be verified only one observation within the gridbox is required. In the second method, a weighted mean of the closest observations to the gridpoint is used, provided that at least two observations on opposite sides of a gridpoint are available. For the third method, the model precipitation forecasts were interpolated to the observation locations.

  14. A diagnostic study of eddy-mean flow interactions during FGGE SOP-1

    Science.gov (United States)

    Baldwin, M. P.; Edmon, H. J., Jr.; Holton, J. R.

    1985-01-01

    Eliassen-Palm (EP) diagrams have been shown to be very useful diagnostics in both the troposphere and the stratosphere. However, the idea that the EP flux divergence is the sole forcing of the mean wind by the eddies can be misleading. A time series of the time rate of change of the zonal mean wind and the EP flux divergence shows that the two quantities were not well correlated during the FGGE special observing period (SOP-1, winter 1979). Calculation of the residual in the zonal momentum equation reveals that considerable negative acceleration (drag) is required to complete the momentum balance in some regions. This residual indicates that not all terms are well represented in atmospheric data sets, and may be largely due to the breaking of vertically propagating gravity waves near the tropopause. Eliassen-Palm diagrams are presented for the FGGE data, as well as Oort's 11-year climatology. The Oort EP diagrams serve as a standard with which to compare other EP diagrams. The FGGE year is shown to be very similar to climatology. A consistent method of displaying the EP flux vectors and divergence is suggested, which has advantages over previous methods.

  15. Adoption of the hybrid CTO approach by a single non-CTO operator: procedural and clinical outcomes

    National Research Council Canada - National Science Library

    Vo, Minh N; McCabe, James M; Lombardi, William L; Ducas, John; Ravandi, Amir; Brilakis, Emmanouil S

    2015-01-01

    ...) of chronic total occlusions (CTOs) has not been described. Consecutive patients who underwent CTO-PCI by a single operator using the "hybrid" approach between 2012 and 2013 formed the analytic cohort...

  16. Peri-operative data on the nuss procedure in children with pectus excavatum: independent survey of the first 20 years' data

    Directory of Open Access Journals (Sweden)

    Athanasiou Thanos

    2008-07-01

    Full Text Available Abstract Objective To review the literature and assess the cumulative data on the Nuss operation in children on its twenty years' anniversary: The Nuss procedure corrects the pectus excavatum by minimal access semi-permanent insertion of metal bars in order to reduce the deformity and refashion the contour of the growing thorax. The advantage over previous techniques is avoidance of osteochondrotomies and thence allowance for normal growth of the thorax. Study design PubMed search was performed. Primary outcomes were mortality, morbidity and individual complications. Secondary outcomes were procedure time and hospital stay. Results We merged the data from 19 reports comprising 1949 children of mean age 10.6 years. No mortality was observed and the procedure was associated with morbidity of 15.4%. The commonest complications are bar-related adverse events (5.7% and pneumothorax (3.5%. The average procedure time and the average hospital stay were 68 minutes and 5.5 days respectively. Conclusion 20 years of initial evidence suggests that the Nuss group of procedures is a safe minimal access option for correction of pectus excavatum in childhood.

  17. Non-thoracoscopic Nuss procedure for correction operation of pectus excavatum%非胸腔镜辅助Nuss手术矫治漏斗胸

    Institute of Scientific and Technical Information of China (English)

    刘文英; 徐冰; 吉毅; 王元祥; 覃道锐

    2008-01-01

    目的 探讨非胸腔镜辅助Nuss手术治疗漏斗胸的手术方法和治疗经验.方法 2005年9月到2007年8月对108例漏斗胸患者行非胸腔镜辅助下Nuss手术,男性91例,女性17例;年龄2岁10个月~25岁,平均年龄7岁9个月;胸廓指数3.6~10.1.结果 108例患者均顺利完成手术,无术中严重并发症发生.平均手术时间40 min,平均术中出血量10 ml.术后患者顺利恢复出院.92例获得随访,随访时间2~21个月,矫形效果满意.结论 非胸腔镜辅助Nuss手术安全可行,并且不用进入胸腔操作,手术创伤更小.%Objective To review the experience in correction operation of pectus excavatum with non-thoracoscopic Nuss procedure. Methods From September 2005 to August 2007 ,108 patients with pectus excavatum were surgically corrected by non-thoracoscopic Nuss procedure. There were 91 male patients and 17 female patients. The age was from 2 years and 10 months old to 25 years old with an average of 7 years and 9 months old. The Haller indexs were from 3.6 to 10.1 before the operation. Results The operation in all patients had been performed successfully without any severe complications. The average time of operation was 40 minutes. The average bleeding volume during procedure was 10 ml. Uneventful recovery was achieved in all the cases. Excellent outcome was obtained in the follow-up of 2 months to 21 months in 92 patients. Conclusions Non-thoracoscopic Nuss procedure for correction of pectus excavatum is safe and effective. It is unnecessary to perform the procedure into thoracic cavity so that there is less trauma and shorter time for the operation.

  18. Establishment of safety analysis system for emergency operating procedures of Kori 3 and 4 and YGN 1 and 2 and reference analyses

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Won Jae; Kim, Hee Cheol; Ha, Kwi Seok; Chung, Bub Dong; Jeong, Jae Jun

    1999-02-01

    This report describes the establishment of safety analysis system for emergency operating procedures(EOPs) of Kori 3 and 4 and YGN 1 and 2 and the results of reference analyses. MARS1.3.1 code has been selected as a realistic system analysis tool of the safety analysis system, and the reactor system has been modeled using a fine nodding scheme in order to capture the major thermal-hydraulic phenomena that might occur during the transients. Full power steady state operating conditions are generated based on the plant operation data. Then, the reference analyses have been carried out for the accidents that can represent the typical EOPtransients, that is, a small-break loss-of-coolant-accident,a main steam line break accident and a steam generator tube rupture accident from the full power operation. For the realistic simulation of plant transient responses, reactor control and protection systems and safety systems are modeled based on their realistic performances. Also, the operator actions are modeled based on the current EOP actions. Through the reference analyses, the soundness of the established safety analysis system and the system modeling has been verified and the effectiveness of the current EOP has been partly justified. In conclusion, the safety analysis system established through this study can be used for the generation of technical background in the development and improvement of EOP actions and in the operator training. (Author). 11 refs., 6 tabs., 48 figs.

  19. A novel operant conflict procedure using incrementing shock intensities to assess the anxiolytic and anxiogenic effects of drugs.

    Science.gov (United States)

    Evenden, John; Ross, Laurie; Jonak, Gerald; Zhou, Jin

    2009-05-01

    There is a need for novel anxiolytics, which are effective, but do not cause sedation, tolerance, and rebound anxiety on discontinuation. To investigate a procedure that can be used to assess these characteristics preclinically, rats were initially trained to press a lever at a high rate to obtain food. Once trained, periods of punishment were introduced in which electric shocks were superimposed. The intensity of these electric shocks was increased every 90 s from very low (0.01 mA) to sufficiently high to stop most subjects responding (0.4 mA), so that a complete rate/intensity function was obtained during each punishment period. The benzodiazepine, chlordiazepoxide, and two novel subtype-selective gamma-aminobutyric acid-A agonists, TP003 and TPA023, significantly increased response rates mildly suppressed by intermediate levels of electric shock without any effect on unpunished response rate. Two clinically anxiogenic agents, yohimbine and flumazenil, reduced the rate of punished responding. Aripiprazole and amphetamine reduced both punished and unpunished responding. Repeated treatment with diazepam 2.5 mg/kg daily for 15 days, initially markedly reduced unpunished response rates, but also increased punished response rates, an effect which became greater with repeated treatment. Abrupt cessation of diazepam treatment produced a reduction in punished responding. Diazepam (5 mg/kg daily) produced a greater reduction in unpunished responding, a smaller increase in punished responding, and a larger and longer lasting reduction in punished rates on withdrawal. In conclusion, the procedure detected anxiolytic and anxiogenic effects of drugs, and the sedative side effects, development of tolerance, and rebound-anxiety on discontinuation of a benzodiazepine. This procedure should have utility in the characterization of novel treatments of anxiety.

  20. Systematic Procedure for Generating Operational Policies to Achieve Target Crystal Size Distribution (CSD) in Batch Cooling Crystallization

    DEFF Research Database (Denmark)

    Abdul Samad, Noor Asma Fazli; Singh, Ravendra; Sin, Gürkan

    Batch cooling crystallization is one of the important unit operations involving separation of solid-liquid phases. Usually the most common crystal product qualities are directly related to the crystal size distribution (CSD). However the main difficulty in batch crystallization is to obtain a uni...

  1. Biometrics: Multi-Service Tactics, Techniques, and Procedures for Tactical Employment of Biometrics in Support of Operations

    Science.gov (United States)

    2016-05-01

    Intelligence Activities Biometrics-Enabled Intelligence USCG Biometrics-at-Sea: Business Rules for...Biometrics in Support of Operations Biometrics-at-Sea: Business Rules for South Florida United States...South Florida, USCG Maritime Law Enforcement Manual Department of Defense Dictionary of Military and

  2. Air sampling procedures to evaluate microbial contamination: a comparison between active and passive methods in operating theatres

    Directory of Open Access Journals (Sweden)

    Napoli Christian

    2012-08-01

    Full Text Available Abstract Background Since air can play a central role as a reservoir for microorganisms, in controlled environments such as operating theatres regular microbial monitoring is useful to measure air quality and identify critical situations. The aim of this study is to assess microbial contamination levels in operating theatres using both an active and a passive sampling method and then to assess if there is a correlation between the results of the two different sampling methods. Methods The study was performed in 32 turbulent air flow operating theatres of a University Hospital in Southern Italy. Active sampling was carried out using the Surface Air System and passive sampling with settle plates, in accordance with ISO 14698. The Total Viable Count (TVC was evaluated at rest (in the morning before the beginning of surgical activity and in operational (during surgery. Results The mean TVC at rest was 12.4 CFU/m3 and 722.5 CFU/m2/h for active and passive samplings respectively. The mean in operational TVC was 93.8 CFU/m3 (SD = 52.69; range = 22-256 and 10496.5 CFU/m2/h (SD = 7460.5; range = 1415.5-25479.7 for active and passive samplings respectively. Statistical analysis confirmed that the two methods correlate in a comparable way with the quality of air. Conclusion It is possible to conclude that both methods can be used for general monitoring of air contamination, such as routine surveillance programs. However, the choice must be made between one or the other to obtain specific information.

  3. Procedural Portfolio Planning in Plastic Surgery, Part 1: Strategic Changes in Clinical Practice to Increase Physician Revenue, Improve Operative Throughput, and Maintain Patient Satisfaction.

    Science.gov (United States)

    Hultman, Charles Scott

    2016-06-01

    Portfolio planning in health care represents the strategic prioritization of services that permits an organization to better achieve its goals of margin and mission. Because of recent volatility in the economy, declining reimbursement, and rising costs of providing care, such strategic planning has become increasingly important if physicians want to remain leaders in health care. This project assesses the financial impact of procedural portfolio planning on an academic plastic surgery practice from the physician's perspective. We tracked the top 50 procedures, defined as total charges per CPT code, that were performed in our baseline year, for 6 providers in a stable plastic surgery practice. At the end of the first year, we implemented 3 types of strategic changes: growth of areas with high contribution margin (laser resurfacing of burn scars), curtailment of high-risk procedures with negative contribution margin (panniculectomy in smokers), and improved efficiency of mission-critical services with high resource consumption (free-flap breast reconstruction). During the 2-year study period, we had no turnover in faculty, did not pursue any formal marketing, did not change our surgical fees or billing system, provided care independent of payer mix, and maintained our commitment to indigent care. Outcome measures included procedural charges and revenue, collection rates, work relative value units, operating room times, idle times (room time less case time), receipts/minute in operating room, uncompensated charity care, and patient satisfaction (Press-Gainey scores). Before the study period, annual incremental growth in our practice was 1% to 2%, in terms of charges and receipts. After implementation of the portfolio planning project, the financial position of our division improved significantly, with patient satisfaction rates increasing from 85.5% to 94.1% and charity care remaining constant at US $400,000 per year. Encounters, work relative value units, charges

  4. A general procedure to evaluate many-body spin operator amplitudes from periodic calculations: application to cuprates

    Energy Technology Data Exchange (ETDEWEB)

    Moreira, Iberio de P R [Departament de Quimica Fisica and Institut de Quimica Teorica i Computacional (IQTCUB), Universitat de Barcelona and Parc CientIfic de Barcelona, C/ MartI i Franques 1, E-08028 Barcelona (Spain); Calzado, Carmen J [Departamento de Quimica Fisica, Universidad de Sevilla, C/ Prof. GarcIa Gonzalez s/n, E-41012 Sevilla (Spain); Malrieu, Jean-Paul [IRSAMC, Laboratoire de Physique Quantique, Universite Paul Sabatier, 118 Route de Narbonne, F-31062 Toulouse-Cedex (France); Illas, Francesc [Departament de Quimica Fisica and Institut de Quimica Teorica i Computacional (IQTCUB), Universitat de Barcelona and Parc CientIfic de Barcelona, C/ MartI i Franques 1, E-08028 Barcelona (Spain)

    2007-10-15

    A general procedure is presented which permits the form of an extended spin Hamiltonian to be established for a given magnetic solid and the magnitude of its terms to be evaluated from spin polarized, Hartree-Fock or density functional calculations carried out for periodic models. The computational strategy makes use of a general mapping between the energy of pertinent broken-symmetry solutions and the diagonal terms of the spin Hamiltonian in a local representation. From this mapping it is possible to determine not only the amplitude of the well-known two-body magnetic coupling constants between near-neighbor sites, but also the amplitudes of four-body cyclic exchange terms. A scrutiny of the on-site spin densities provides additional information and control of the many broken-symmetry solutions which can be found. The procedure is applied to the La{sub 2}CuO{sub 4}, Sr{sub 2}CuO{sub 2}F{sub 2}, Sr{sub 2}CuO{sub 2}Cl{sub 2} and Ca{sub 2}CuO{sub 2}Cl{sub 2} square lattices and the SrCu{sub 2}O{sub 3} ladder compound. It is shown that a proper description of the magnetic structure of these compounds requires that two- and four-body terms are explicitly included in the spin Hamiltonian. The implications for the interpretation of recent experiments are discussed.

  5. 沙门菌SopB蛋白在侵袭宿主细胞中的作用机制%Mechanism of Salmonella SopB protein in invasion of host cells

    Institute of Scientific and Technical Information of China (English)

    郭梦征; 陈乃耀; 阮海华

    2013-01-01

    Salmonella is a gram-negative enteric bacteria,the infection of the host can cause a variety of diseases,such as severe gastroenteritis,which impacts on human health.Encoded by Salmonella SPI-1 and secreted by type Ⅱ secretion system,SopB is transported to the host cell through a "trigger" mechanism and regulate the function of the host cell.SopB plays a generalist role in multiple biological functions,such as the mediated cytoskeletal rearrangements,promoting Akt phosphorylation to inhibite apoptosis,activation of nitric oxide synthase (iNOS),and can induce Salmonella containing vesicles (SCV),providing for a micro-environment for the survival and proliferation of Salmonella in host cells.%沙门菌是一种革兰阴性肠道病原菌,其通过“触发”机制,依赖沙门菌致病岛(Salmonella pathogenicity island, SPI)编码的Ⅲ型分泌系统(type Ⅲ secretion system,T3SS)将效应蛋白转运至宿主细胞,调节宿主细胞功能.SopB是SPI-1编码的效应分子之一,其在沙门菌侵袭宿主细胞过程中发挥多重生物学功能,如介导细胞骨架重排,促使Akt发生磷酸化修饰进而抑制细胞凋亡,激活一氧化氮合酶(iNOS),并能诱导沙门菌包含小泡(Salmonella containing vacuole,SCV)的初步形成及成熟,为沙门菌在宿主细胞内的存活及增殖提供了一个微环境.

  6. On convection and static stability during the AMMA SOP3 campaign

    Science.gov (United States)

    Embolo Embolo, G. B.; Lenouo, André; Nzeukou, Armand T.; Vondou, Derbetini A.; Kamga, F. Mkankam

    2017-01-01

    Using radiosonde dataset from 15 weather stations over West Africa, this paper investigates the contribution of the couple convection-static stability in the framework of the African monsoon multidisciplinary analyses Special Observing Period 3 (AMMA SOP3) experiment. Within this 31-day period, the boundary layer-winds depictions have revealed the West African monsoon's (WAM) depth (around 1500 m) is not thick enough to trigger intense convection. However, the midlevel winds distribution (700-600 hPa) has shown the average African easterly jet core strength (15 m s-1) is sufficient to allow the development of African easterly waves (AEWs) necessary for squall lines activities. In return, in the upper levels (200-100 hPa), the speed (below 18 m s-1) of the mean Tropical easterly jet (TEJ) core cannot favor midlevel updrafts. The free tropospheric humidity (FTH) depiction has indicated convective events are more likely in the western Sahel where the highest FTH (FTH >50 %) are recorded. The static stability analysis has testified that convection is stronger in the semi-arid (SA) area during night time (0000 GMT). However, convective activities are inhibited in the wet equatorial (WE) region due to mean low-level stability. We used METEOSAT Second Generation (MSG) infrared (IR10.8) imagery of the 8th September 2006 to confirm that result. Furthermore, a maximum midtropospheric static stability combined with maximum relative humidity (RH) was found on the fringe of the Saharan air layer's (SAL) top (altitude around 5.3 km) in the WE region.

  7. The Vienna comparative cognition technology (VCCT): an innovative operant conditioning system for various species and experimental procedures.

    Science.gov (United States)

    Steurer, Michael Morten; Aust, Ulrike; Huber, Ludwig

    2012-12-01

    This article describes a laboratory system for running learning experiments in operant chambers with various species. It is based on a modern version of a classical learning chamber for operant conditioning, the so-called "Skinner box". Rather than constituting a stand-alone unit, as is usually the case, it is an integrated part of a comprehensive technical solution, thereby eliminating a number of practical problems that are frequently encountered in research on animal learning and behavior. The Vienna comparative cognition technology combines modern computer, stimulus presentation, and reinforcement technology with flexibility and user-friendliness, which allows for efficient, widely automatized across-species experimentation, and thus makes the system appropriate for use in a broad range of learning tasks.

  8. A summary of the test procedures and operational details of an ocean dumping pollution monitoring experiment conducted 7 October 1976

    Science.gov (United States)

    Hypes, W. D.; Wallace, J. W.; Gurganus, E. A.

    1977-01-01

    A remote sensor experiment was conducted at a sewage sludge dump site off the Delaware/Maryland coast. Two aircraft serving as remote sensor platforms flew over the dump site during a sludge dump. One aircraft carried a multispectral scanner and the other aircraft carried a rapid scanning spectrometer. Data from sea-truth stations were collected concurrent with overpasses of the aircraft. All sensors were operational and produced good digital data.

  9. Analysis of operational manning requirements and deployment procedures for unmanned surface vehicles aboard U.S. Navy ships

    OpenAIRE

    2006-01-01

    This research was conducted in association with Naval Warfare Development Command (NWDC) requests to update Unmanned Vehicle Tactical Memorandum TM-3-22- 5-SW. The research identified and discussed significant USV manning considerations such as source ratings and manpower qualities to pilot, operate sensors, support USV electronics, and the manpower implications associated with various weapons systems alternatives. In addition, this research described several existing and notional USV ta...

  10. Operative procedures of single-incision laparoscopic repair of pediatric epigastric hernia have become simple and feasible with the use of a novel suture-assisting needle

    Directory of Open Access Journals (Sweden)

    Kyoichi Deie

    2016-01-01

    Full Text Available We describe a simple and feasible procedure for single-incision laparoscopic repair of a pediatric epigastric hernia using a novel suture-assisting needle. A multichannel port was inserted through the umbilical vertical incision. After the orifice of the hernia was identified, a suture-assisting needle, which can hold a suture at its tip, with a 2-0 thread was pierced through the skin into one side of the rectus muscle sheath into the abdominal cavity. Next, after releasing the thread, the needle was pulled out to the subcutis and pierced through another side of the rectus muscle sheath. The needle, grasping the thread again, was subsequently pulled out through the abdominal wall outside, and the thread was tied extracorporeally. This knot was buried subcutaneously. Operative procedures of single-incision laparoscopic repair of an epigastric hernia have become simple and feasible with the use of a novel suture-assisting needle with an excellent cosmetic result.

  11. The Latarjet procedure for the treatment of recurrence of anterior instability of the shoulder after operative repair: a retrospective case series of forty-nine consecutive patients.

    Science.gov (United States)

    Schmid, Samuel L; Farshad, Mazda; Catanzaro, Sabrina; Gerber, Christian

    2012-06-06

    Recurrence of anterior shoulder instability after operative repair is an uncommon but disabling condition for which treatment options have been insufficiently studied. Coracoid transfer as described by Latarjet is a highly successful primary operation for recurrent anterior shoulder instability. The purpose of this study was to verify the hypothesis that this procedure is also effective for treating recurrent glenohumeral instability after previous operative repair. Forty-nine consecutive patients with either one (n = 32), two (n = 12), or at least three (n = 5) previous stabilizations other than a Latarjet procedure and recurrence of anterior glenohumeral instability associated with a lesion of the anterior aspect of the glenoid rim had revision with a coracoid transfer as described by Latarjet. Clinical outcomes at a mean of thirty-eight months postoperatively included the subjective shoulder value, the Constant-Murley score, and glenohumeral stability. Standardized anteroposterior and axial radiographs before and after the Latarjet revision were used to grade the degree of glenohumeral osteoarthritis. The results in all forty-nine patients were reviewed. No shoulder redislocated, subluxations recurred in two patients, and five patients reported slight, unspecified shoulder symptoms. No revision surgery was needed. Forty-three shoulders (88%) were subjectively graded as excellent or good; three, fair; and three, poor. Dissatisfaction was associated with persistent pain, and patients with preoperative pain had a twentyfold higher probability of having postoperative pain. The mean subjective shoulder value increased from 53% preoperatively to 79% at the time of follow-up (p Latarjet can effectively restore anterior glenohumeral shoulder stability if previous operation(s) have failed to do so. If recurrence is associated with chronic pain, the pain is likely to persist and compromise the subjective outcome.

  12. Predominance of Procedural Knowledge and Between-Operation Interference as Deduced from Fraction Errors of Preservice Teachers

    Directory of Open Access Journals (Sweden)

    Amancio L. Cantoria, Jr.

    2016-11-01

    Full Text Available The study of fractions in Philippine mathematics curriculum starts as early as first grade. In spite of the regular rehearsal of this mathematical topic through secondary school level, many students reach college without showing adequate skills in fraction. This study determined the performance and analyzed the errors of preservice teachers in dealing with fractions. Findings revealed that preservice teachers’ performance in solving fractions reached an unacceptable level. Prevalent errors were demonstrated when adding dissimilar fractions, adding a mixed number and a fraction, and multiplying a mixed number by a fraction, because the dominant procedural knowledge in fraction addition interferes with their knowledge of fraction multiplication, and vice versa. Moreover, preservice teachers exhibit low level of content knowledge of fractions as shown in their inability to add common fractions and their failure to translate mixed numbers into equivalent fractions.

  13. Analysis of the effect of operator splitting and of the sampling procedure on the accuracy of Glimm's method

    Energy Technology Data Exchange (ETDEWEB)

    Colella, P.

    1978-12-01

    A study is made of Glimm's method, a method for constructing approximate solutions to systems of hyperbolic conservation laws in one space variable by sampling explicit wave solutions. It is extended to several space variables by operator splitting. Two fundamental problems are addressed. A highly accurate form of the sampling procedure, in one space variable, based on the van der Corput sampling sequence is proposed. Error bounds are derived for Glimm's method, with van der Corput sampling, as applied to the inviscid Burgers' equation: for sufficiently small times the error in shock locations, speeds, and strengths is no greater than O(h/sup 1/2/abs. value (log h)), and the error in the continuous part of the solution, away from shocks, is O(h abs. value (log h)). Here h is the spatial increment of the grid, with the estimates holding in the limit of h ..-->.. 0. The improved sampling procedure is tested numerically in the case of inviscid compressible flow in one space dimension; it gives high-resolution results both in the smooth parts of the solution and at discontinuities. The operator splitting procedure by means of which the multidimensional method is constructed is investigated. An O(1) error stemming from the use of this procedure near shocks oblique to the spatial grid is analyzed numerically in the case of the equations for inviscid compressible flow in two space dimensions, and a method for eliminating this error, by the use of suitable artificial viscosity, is proposed and tested. 33 figures.

  14. Performance of the European System for Cardiac Operative Risk Evaluation II: a meta-analysis of 22 studies involving 145,592 cardiac surgery procedures.

    Science.gov (United States)

    Guida, Pietro; Mastro, Florinda; Scrascia, Giuseppe; Whitlock, Richard; Paparella, Domenico

    2014-12-01

    A systematic review of the European System for Cardiac Operative Risk Evaluation (euroSCORE) II performance for prediction of operative mortality after cardiac surgery has not been performed. We conducted a meta-analysis of studies based on the predictive accuracy of the euroSCORE II. We searched the Embase and PubMed databases for all English-only articles reporting performance characteristics of the euroSCORE II. The area under the receiver operating characteristic curve, the observed/expected mortality ratio, and observed-expected mortality difference with their 95% confidence intervals were analyzed. Twenty-two articles were selected, including 145,592 procedures. Operative mortality occurred in 4293 (2.95%), whereas the expected events according to euroSCORE II were 4802 (3.30%). Meta-analysis of these studies provided an area under the receiver operating characteristic curve of 0.792 (95% confidence interval, 0.773-0.811), an estimated observed/expected ratio of 1.019 (95% confidence interval, 0.899-1.139), and observed-expected difference of 0.125 (95% confidence interval, -0.269 to 0.519). Statistical heterogeneity was detected among retrospective studies including less recent procedures. Subgroups analysis confirmed the robustness of combined estimates for isolated valve procedures and those combined with revascularization surgery. A significant overestimation of the euroSCORE II with an observed/expected ratio of 0.829 (95% confidence interval, 0.677-0.982) was observed in isolated coronary artery bypass grafting and a slight underestimation of predictions in high-risk patients (observed/expected ratio 1.253 and observed-expected difference 1.859). Despite the heterogeneity, the results from this meta-analysis show a good overall performance of the euroSCORE II in terms of discrimination and accuracy of model predictions for operative mortality. Validation of the euroSCORE II in prospective populations needs to be further studied for a continuous

  15. The incidence and nature of adverse events during pediatric sedation/anesthesia with propofol for procedures outside the operating room: a report from the Pediatric Sedation Research Consortium.

    Science.gov (United States)

    Cravero, Joseph P; Beach, Michael L; Blike, George T; Gallagher, Susan M; Hertzog, James H

    2009-03-01

    We used a large database of prospectively collected data on pediatric sedation/anesthesia outside the operating room provided by a wide range of pediatric specialists to delineate the nature and frequency of adverse events associated with propofol-based sedation/anesthesia care. Data were collected by the Pediatric Sedation Research Consortium, a collaborative group of institutions dedicated to improving sedation/anesthesia care for children internationally. Members prospectively enrolled consecutive patients receiving sedation or sedation/anesthesia for procedures. The primary inclusion criterion was the need for some form of sedation/anesthesia to perform a diagnostic or therapeutic procedure outside the operating room. There were no exclusion criteria. Data on demographics, primary illness, coexisting illness, procedure performed, medications used, procedure and recovery times, medication doses outcomes of anesthesia, airway interventions and adverse events were collected and reported using web-based data collection tool. For this study, we evaluated all instances where propofol was used as the primary drug in the sedation/anesthesia technique. Thirty-seven locations submitted data on 49,836 propofol sedation/anesthesia encounters during the study period from July 1, 2004 until September 1, 2007. There were no deaths. Cardiopulmonary resuscitation was required twice. Aspiration during sedation/anesthesia occurred four times. Less serious events were more common with O(2) desaturation below 90% for more than 30 s, occurring 154 times per 10,000 sedation/anesthesia administrations. Central apnea or airway obstruction occurred 575 times per 10,000 sedation/anesthesia administrations. Stridor, laryngospasm, excessive secretions, and vomiting had frequencies of 50, 96, 341, and 49 per 10,000 encounters, respectively. Unexpected admissions (increases in levels of care required) occurred at a rate of 7.1 per 10,000 encounters. In an unadjusted analysis, the rate of

  16. A field test of substance use screening devices as part of routine drunk-driving spot detection operating procedures in South Africa.

    Science.gov (United States)

    Matzopoulos, Richard; Lasarow, Avi; Bowman, Brett

    2013-10-01

    This pilot study aimed to test four substance use screening devices developed in Germany under local South African conditions and assess their utility for detecting driving under the influence of drugs (DUID) as part of the standard roadblock operations of local law enforcement agencies. The devices were used to screen a sample of motorists in the Gauteng and Western Cape provinces. The motorists were diverted for screening at roadblocks at the discretion of the law enforcement agencies involved, as per their standard operating procedures. Fieldworkers also administered a questionnaire that described the screening procedure, as well as information about vehicles, demographic information about the motorists and their attitudes to the screening process during testing. Motorists tested positive for breath alcohol in 28% of the 261 cases tested. Oral fluid was screened for drugs as per the standard calibrated cut-offs of all four devices. There were 14 cases where the under-influence drivers tested positive for alcohol and drugs simultaneously, but 14% of the 269 drivers drug-screened tested positive for drugs only. After alcohol, amphetamine, methamphetamine and cocaine were the most common drugs of impairment detected. The results suggest that under normal enforcement procedures only 76% of drivers impaired by alcohol and other drugs would have been detected. In more than 70% of cases the tests were administered within 5 min and this is likely to improve with more regular use. It was clear that the pilot screening process meets global testing standards. Although use of the screening devices alone would not serve as a basis for prosecution and provisions would need to be made for the confirmation of results through laboratory testing, rollout of this screening process would improve operational efficiency in at least two ways. Firstly, the accuracy of the tests will substantially decrease confirmatory test loads. Secondly, laboratory drug testing can be restricted to

  17. A model for the value of a business, some optimization problems in its operating procedures and the valuation of its debt

    Science.gov (United States)

    1997-12-01

    In this paper we present a model for the value of a firm based on observable variables and parameters: the annual turnover, the expenses, interest rates. This value is the solution of a parabolic partial differential equation. We show how the value of the company depends on its legal status such as its liability (that is, whether it is a Limited Company or a sole trader/partnership). We give examples of how the operating procedures can be optimized (for example, whether the firm should close down, relocate etc.). Finally, we show how the model can be used to value the debt issued by the firm.

  18. Scheduling Operative Surgical Services to Recover CHAMPUS Surgical Procedures at Blanchfield Army Community Hospital, Fort Campbell, Kentucky

    Science.gov (United States)

    1993-08-01

    any given date range, the report sub-totals the number of each type of anesthesia used ( general , local , etc.). 68 Ippendiz D Operating Roon Report by...46 5359 UMBILICAL HERNIA REPAIR 33 59:20 1:48 5300 LEFT INGUINAL HERNIA REPAIR 164 294:38 1:48 470 APPENDECTOMY 64 121:03 1:53 3859 LIG/STRIPPING OF...VARCOSE VEINS 21 45:50 2:10 9999 OTHER 277 617:42 2:13 5310 BILAT INGUINAL HERNIA REP 13 29:30 2:16 5421 DIAGNOSTIC LAPAROSCOPY 6 14:40 2:27 5351

  19. Prevalencia de Neospora caninum y DVB en una finca con problemas reproductivos en Sopó (Cundinamarca)

    OpenAIRE

    John Fredy García-Chaparro; Giovanni Moreno-Figueredo; Anastasia Catalina Cruz-Carrillo

    2015-01-01

    La investigación tuvo como objetivo determinar la prevalencia de Neospora caninum y del virus de la diarrea viral bovina (DVB) en bovinos de una finca con problemas reproductivos, en el municipio de Sopó (Cundinamarca), y su relación con la presentación de abortos. Se tomaron muestras de suero sanguíneo de 397 animales de alta producción lechera y con antecedentes reproductivos, seleccionados al azar.Se utilizó la inmunofluoresencia indirecta para la N. caninum, y seroneutralización para DVB,...

  20. Synchronous One-Pot (SOP) synthesis of hybrid structures: metal nanoparticles in self-assemblies of amphiphilic calix[6]biscrowns.

    Science.gov (United States)

    Liang, Qing; Li, Changxi; Chen, Guosong; Jiang, Ming

    2012-10-01

    In this paper, we present a novel strategy, named Synchronous One-Pot (SOP) synthesis, to prepare gold nanoparticles (AuNPs) with a diameter of 2nm incorporated in self-assembled organic spheres with a diameter around 60nm (denoted as NPAs). Merits of this method include: (1) self-assembly of the organic component (calix[6]biscrown TAC) into spheres and the reduction of chloroauric acid (HAuCl(4)) take place simultaneously; (2) preparation combining UV irradiation and formaldehyde addition reduces the size and homogenizes the distribution of the resultant AuNPs within the TAC spheres. (3) Obtained material NPA gives attractive catalytic property to hydrogenation reaction.

  1. THE FINANCING OF THE ACTIVITIES WITHIN THE SECTORIAL OPERATIONAL PROGRAMME “INCREASE OF ECONOMIC COMPETITIVENESS”

    Directory of Open Access Journals (Sweden)

    Vasile POPEANGĂ

    2009-12-01

    Full Text Available The Sectorial Operational Programme “Increase of Economic Competitiveness” (further referred to as SOP IEC is one of the seven instruments (OPs, under the Convergence objective, for achieving the priorities of the National Strategic Reference Framework (NSRF derived from the National Development Plan 2007 – 2013 (NDP, which aims to strengthen the strategic focus of the Economic and Social Cohesion policies across Romania, and to make the correct and appropriate linkages to the European policies and the Lisbon Strategy for growth and job creation. SOP IEC was elaborated under the coordination of the Managing Authority for SOP IEC -Ministry of Economy and Finance (MEF, and is the result of the partnership consultations both with the strategic partners (ACIS within MEF, other MAs–ministries coordinating other OPs, institutions designated as Intermediate Bodies, other line ministries, and agencies, social partners, civil society organizations, potential beneficiaries, other stakeholders involved in this field.

  2. Submicron Particles during Macro- and Micro-Weldings Procedures in Industrial Indoor Environments and Health Implications for Welding Operators

    Directory of Open Access Journals (Sweden)

    Pasquale Avino

    2015-06-01

    Full Text Available One of the emerging risks in the engineering and electronic industries is the exposure of workers to ultrafine particles during (micro-welding operations, i.e., processes used for joining two metal parts heated locally, which constitute the base metal, with or without addition of another metal which is the filler metal, melted between the edges to be joined. The process is accompanied by formation of metallic fumes arising from the molten metal as well as by the emission of metal fumes of variable composition depending on the alloys welded and fused. The aim of this paper is to investigate the number, concentration and size distribution of submicron particles produced by (micro-welding processes. Particle number size distribution is continuously measured during (micro-welding operations by means of two instruments, i.e., Fast Mobility Particle Sizer and Nanoparticle Surface Area Monitor. The temporal variation of the particle number size distribution across the peaks evidences the strong and fast-evolving contribution of nucleation mode particles: peak values are maintained for less than 10 s. The implication of such contribution on human health is linked to the high deposition efficiency of submicronic particles in the alveolar interstitial region of the human respiratory system, where gas exchange occurs.

  3. Regulation of the Caenorhabditis elegans posterior Hox gene egl-5 by microRNA and the polycomb-like gene sop-2.

    Science.gov (United States)

    Zhang, Hongjie; Emmons, Scott W

    2009-03-01

    In Caenorhabditis elegans, the domains of Hox gene expression are controlled by the novel global regulatory gene sop-2. We identified a region located 3' of the Hox gene egl-5 that promotes ectopic expression of an egl-5 reporter gene in a sop-2 mutant. SOP-2 could directly block positive regulatory factors acting in this region, or it could block their expression. We identified three possible miRNA binding sites within the egl-5 3' untranslated region (UTR). Cognate microRNAs are expressed in relevant tissues and can block egl-5 expression when expressed from a transgene. Mutation of the putative binding sites in the egl-5 3'UTR resulted in a modest degree of misexpression of a minimal egl-5 reporter gene, suggesting that microRNAs may contribute to the tight restriction of egl-5 expression to particular cell lineages.

  4. Understanding text after severe closed-head injury: assessing inferences and memory operations with a think-aloud procedure.

    Science.gov (United States)

    Schmitter-Edgecombe, Maureen; Bales, James W

    2005-09-01

    A think-aloud method was used to examine the content of information available to working memory during narrative comprehension in a CHI population. Twenty severe CHI participants (>1 year post-injury) and 20 controls talked aloud after they read each sentence of story narratives. Trabasso and Magliano's (1996a) verbal protocol analysis was then used to code for the production of inferential and non-inferential clauses and the memory operations that supported inferential clause production. We found that CHI and control groups produced a comparable number of clauses, that inferences dominated narrative comprehension, and that both groups produced more explanatory inferences than predictive or associative inferences. Despite these qualitative similarities, the CHI group demonstrated poorer comprehension, generated proportionately fewer inferences, relied less on retrieval as a memory source for explanatory inferences, and produced more non-inferential clauses and associative inferences.

  5. A Development Method of Mobile Computerized Procedure System for the Cooperation among Field Workers and Main Control Room Operators in Korean Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Sun Jin; Seong, No Kyu; Jung, Yeon Sub [KHNP ,Daejeon (Korea, Republic of)

    2014-08-15

    Human errors can occur during the test and maintenance of steam generator, safety injection system and other various systems and devices in nuclear power plants (NPPs). Most of human errors can be improved by the human error prevention techniques such as self-check, peer-check, concurrent verification and etc. Another important technique is to share work information among main control room (MCR) operators and field workers. Various field service automation tools have been developed with recent information technology in many countries. APR1400 computerized procedure system (CPS) has been developed for the MCR operators of Shin-Kori 3 and 4 units. Especially, the concurrent verification support design is applied in the construction project of Shin-Hanul 1 and 2 CPS. It is expected that the proposed mobile CPS can enhance the reduction of human errors by supporting human error prevention techniques and information sharing. This paper describes the technical issues of the mobile CPS (mobile CPS) in the initial development stage. Based on the design of APR1400, CRI CPS has been developed and operated for SKN 3 and 4 HFE V and V and license test for the MCR operating staff. Therefore the mobile CPS will be developed by upgrading the CRI CPS with improved features.

  6. Advantages of SOP Technology and Its Application in RF Domain%SOP技术的优势以及在射频领域的应用

    Institute of Scientific and Technical Information of China (English)

    张欣欣; 王鲁豫

    2007-01-01

    通过对单芯片系统(SOC)、多芯片组件(MCM)、封装内的系统(SIP)和单封装系统(SOP)几种重要封装技术的分析比较,展示了SOP技术的显著优势,其优势使之更加适用于未来电子系统的发展.SOP在射频领域已有比较成功的应用,文中同时介绍了几种典型的射频S0P(RF-SOP)结构.

  7. Computerized procedures system

    Science.gov (United States)

    Lipner, Melvin H.; Mundy, Roger A.; Franusich, Michael D.

    2010-10-12

    An online data driven computerized procedures system that guides an operator through a complex process facility's operating procedures. The system monitors plant data, processes the data and then, based upon this processing, presents the status of the current procedure step and/or substep to the operator. The system supports multiple users and a single procedure definition supports several interface formats that can be tailored to the individual user. Layered security controls access privileges and revisions are version controlled. The procedures run on a server that is platform independent of the user workstations that the server interfaces with and the user interface supports diverse procedural views.

  8. Operation and calibration of the Silicon Drift Detectors of the ALICE experiment during the 2008 cosmic ray data taking period

    CERN Document Server

    Alessandro, B; Bala, R; Batigne, G; Beolè, S; Biolcati, E; Bock Garcia, N; Bruna, E; Cerello, P; Coli, S; Corrales Morales, Y; Costa, F; Crescio, E; De Remigis, P; Di Liberto, S; Falchieri, D; Feofilov, G; Ferrarese, W; Gandolfi, E; Garcia, C; Gaudichet, L; Giraudo, G; Giubellino, P; Humanic, T J; Igolkin, S; Idzik, M; Kiprich, S K; Kisiel, A; Kolozhvari, A; Kotov, I; Kral, J; Kushpil, S; Kushpil, V; Lea, R; Lisa, M A; Martinez, M I; Marzari Chiesa, A; Masera, M; Masetti, M; Mazza, G; Mazzoni, M A; Meddi, F; Montano Zetina, L M; Monteno, M; Nilsen, B S; Nouais, D; Padilla Cabal, F; Petrácek, V; Poghosyan, M G; Prino, F; Ramello, L; Rashevsky, A; Riccati, L; Rivetti, A S; Senyukov, S; Siciliano, M; Sitta, M; Subieta Vasquez, M A; Sumbera, M L; Toscano, L; Tosello, F; Truesdale, D; Urciuoli, G M; Vacchi, A; Vallero, S; Werbrouck, A; Zampa, G; Zinovjev, G

    2010-01-01

    The calibration and performance of the Silicon Drift Detector of the ALICE experiment during the 2008 cosmic ray run will be presented. In particular the procedures to monitor the running parameters (baselines, noise, drift speed) are detailed. Other relevant parameters (SOP delay, time-zero, charge calibration) were also determined.

  9. Factors Affecting the Use of Human Tissues in Biomedical Research: Implications in the Design and Operation of a Biorepository.

    Science.gov (United States)

    Atherton, Daniel S; Sexton, Katherine C; Otali, Dennis; Bell, Walter C; Grizzle, William E

    2016-01-01

    The availability of high-quality human tissues is necessary to advance medical research. Although there are inherent and induced limitations on the use of human tissues in research, biorepositories play critical roles in minimizing the effects of such limitations. Specifically, the optimal utilization of tissues in research requires tissues to be diagnosed accurately, and the actual specimens provided to investigators must be carefully described (i.e., there must be quality control of each aliquot of the tissue provided for research, including a description of any damage to tissues). Tissues also should be collected, processed, stored, and distributed (i.e., handled) uniformly under a rigorous quality management system (QMS). Frequently, tissues are distributed to investigators by tissue banks which have collected, processed, and stored them by standard operating procedures (SOPs). Alternatively, tissues for research may be handled via SOPs that are modified to the specific requirements of investigators (i.e., using a prospective biorepository model). The primary goal of any type of biorepository should be to ensure its specimens are of high quality and are utilized appropriately in research; however, approaches may vary based on the tissues available and requested. For example, extraction of specific molecules (e.g., microRNA) to study molecular characteristics of a tissue may require less clinical annotation than tissues that are utilized to identify how the molecular expression might be used to clarify a clinical outcome of a disease or the response to a specific therapy. This review focuses on the limitations of the use of tissues in research and how the design and operations of a tissue biorepository can minimize some of these limitations.

  10. GPS Zenith Total Delays and Precipitable Water in comparison with special meteorological observations in Verona (Italyduring MAP-SOP

    Directory of Open Access Journals (Sweden)

    S. Corradini

    2002-06-01

    Full Text Available Continuous meteorological examination of the Pre-Alpine zones in Northern Italy (Po Valleyis important for determination of atmospheric water cycles connected with floods and rainfalls.During a special meteorological observing period (MAP-SOP,radiosounding and other measurements were made in the site of Verona (Italy. This paper deals with Zenith Total Delay (ZTDand Precipitable Water (PWcomparisons obtained by GPS, radiosounding and other meteorological measurements.PW and ZTD from ground-based GPS data in comparisonwith classical techniques (e.g.,WVR,radiosoundingfrom recent literature present an accurate tool for use in meteorology applications (e.g.,assimilation in Numerical Weather Prediction (NWPmodels on short-range precipitation forecasts.Comparison of such ZTD for MAP-SOP showed a standard deviation of 16.1 mm and PW comparison showed a standard deviation of 2.7 mm,confirming the accuracy of GPS measurements for meteorology applications.In addition,PW data and its time variation are also matched with time series of meteorological situations.Those results indicate that changes in PW values could be connected to changes in air masses,i.e.to passages of both cold and warm fronts.There is also a correlation between precipitation, forthcoming increase and the following decrease of PW.A good agreement between oscillation of PW and precipitation and strong cyclonic activities is found.

  11. 改良Nuss手术矫治小儿漏斗胸的手术配合%Operation Cooperation in Modified Nuss Procedure for Pectus Excavatum

    Institute of Scientific and Technical Information of China (English)

    陈琨琨; 周琦; 雷英

    2011-01-01

    目的 探讨和分析改良Nuss术的手术配合要点,以提高工作效率和质量.方法 对50例漏斗胸患儿进行术前访视,做好心理护理,认真准备手术物品.术中密切观察手术进程,保持密切配合.结果 所有50例患儿均顺利完成手术,无术中并发症、死亡及复发病例.手术时间40~60 min,平均45 min;术中出血10~25 ml,平均出血10ml;住院时间6~10d,平均住院时间7d.术后伤口皮下淤血2例,矫形板轻度翻转1例.随访1~12个月,平均10个月.患儿活动量明显增加,对矫形效果满意.结论 改良Nuss术矫治小儿漏斗胸具有创伤小、切口小而隐蔽、手术时间短、出血少、术后活动早、矫形效果好等优点.术前对患儿的全面评估、充分的物品准备,术中与医生的默契配合是手术成功的重要保障.%Objective To investigate and analyze the key points of cooperation in the operation of modified Nuss procedure for the pectus excavatum and to improve the efficiency and quality of work. Methods The pre-operative interview and psychological nursing were carried out in 50 children with pectus excavatum. The surgical items were carefully prepared before surgery. According to the process, the closely cooperation with the operator was conducted. Results The operations for all of SO cases of children were accomplished favorably. There were no complications and death or relapse cases. The time of surgery was 40-60 minutes (mean 45 minutes). The volume of hemorrhage was 10-25 ml( mean 10 ml). The time in hospital was 6-10 days( mean 7 days). Two cases were with postoperative skin congestion,and one case with mild flipping of orthopaedic board. Conclusion There are many advantages of modified Nuss procedure,such as slight trauma, small and concealed cut,short time of operation, little hemorrhage,early activity after surgery and good orthoraedic effect. The comprehensive evaluation of children' s condition before operation

  12. The dangers of lithotomy positioning in the operating room: case report of bilateral lower extremity compartment syndrome after a 90-minutes surgical procedure.

    Science.gov (United States)

    Stornelli, Nicole; Wydra, Frank B; Mitchell, Justin J; Stahel, Philip F; Fabbri, Stefka

    2016-01-01

    Lower extremity acute compartment syndrome after gynecologic surgery in the lithotomy position is a rare, yet potentially devastating complication. A high level of suspicion is paramount for early recognition and mitigation of acute compartment syndrome originating from prolonged surgery in lithotomy position. A 23-year-old female, gravida 1, para 0, underwent a laparoscopic salpingectomy for a ruptured ectopic pregnancy. Surgical time was 90 min. Postoperatively, the patient developed acute compartment syndrome of both legs necessitating emergent bilateral four-compartment fasciotomies, with repeated returns to the operating room for 2nd look procedures and delayed wound closures. The patient regained full function within 3 months and returned to an unrestricted baseline activity level. Technical diligence in applying a lithotomy position is paramount for preventing postoperative lower extremity compartment syndrome. A high level of suspicion for this severe complication in conjunction with early recognition and immediate surgical management can mitigate long-term adverse sequelae and improve postoperative outcomes.

  13. Sunshine School's S.O.P.: Sequenced Objectives for Preschoolers. An Evaluation and Instruction Guide for Working with the Developmentally Delayed.

    Science.gov (United States)

    Sunshine School, Gainesville, FL.

    Developed by professional educational staff, the curriculum of developmentally sequenced objectives for preschoolers (SOP) is designed for use in infant stimulation programs, for preschool training for all levels of retardation, with severely and profoundly retarded school age children, and for trainable and educable children during the earlier…

  14. Software Operational Profile Based Test Case Allocation Using Fuzzy Logic

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Software operational profile (SOP) is used in software reliability prediction, software quality assessment, performance analysis of software, test case allocation, determination of "when to stop testing," etc. Due to the limited data resources and large efforts required to collect and convert the gathered data into point estimates, reluctance is observed by the software professionals to develop the SOP. A framework is proposed to develop SOP using fuzzy logic, which requires usage data in the form of linguistics. The resulting profile is named fuzzy software operational profile (FSOP). Based on this work, this paper proposes a generalized approach for the allocation of test cases, in which occurrence probability of operations obtained from FSOP are combined with the criticality of the operations using fuzzy inference system (FIS). Traditional methods for the allocation of test cases do not consider the application in which software operates. This is intuitively incorrect. To solve this problem, allocation of test cases with respect to software application using the FIS model is also proposed in this paper.

  15. Differential expression of Salmonella type III secretion system factors InvJ, PrgJ, SipC, SipD, SopA and SopB in cultures and in mice.

    Science.gov (United States)

    Gong, Hao; Vu, Gia-Phong; Bai, Yong; Yang, Edward; Liu, Fenyong; Lu, Sangwei

    2010-01-01

    The type III secretion system (T3SS) encoded by Salmonella pathogenicity island 1 (SPI-1) is important for the invasion of epithelial cells during development of Salmonella-associated enterocolitis. It has been suggested that the level and timing of the expression of the SPI-1 T3SS proteins and effectors dictate the consequences of bacterial infection and pathogenesis. However, the expression of these proteins has not been extensively studied in vivo, especially during the later stages of salmonellosis when the infection is established. We have constructed recombinant Salmonella strains that contain a FLAG epitope inserted in-frame to genes invJ, prgJ, sipC, sipD, sopA and sopB, and investigated the expression of the tagged proteins both in vitro and in vivo during murine salmonellosis. Mice were inoculated intraperitoneally or intragastrically with the tagged Salmonella strains. At different time points post-infection, bacteria were recovered from various organs, and the expression of the tagged proteins was determined. Our results provide direct evidence that PrgJ and SipD are expressed in Salmonella colonizing the liver and ileum of infected animals at both the early and late stages of infection. Furthermore, our study has shown that the InvJ protein is expressed preferentially in Salmonella colonizing the ileum but not the liver, while SipC is expressed preferentially in Salmonella colonizing the liver but not the ileum. Thus, Salmonella appears to express different SPI-1 proteins and effectors when colonizing specific tissues. Our results suggest that differential expression of these proteins may be important for tissue-specific aspects of bacterial pathogenesis such as gastroenterititis in the ileum and systemic infection in the liver.

  16. Standing Operating Procedures Hostage Situations

    Science.gov (United States)

    1977-06-10

    spiritual standards. The hostage must be realistic in his priorities since one must accept treatment in a crisis situation that would be unacceptable...and McCord, Joan. Psychopathy and Delinquency. New York« Grune and Stratton, 1956. "Media and the Taking of Hostages-Netherlands," Algemeen

  17. Applications for a hybrid operating room in thoracic surgery: from multidisciplinary procedures to --image-guided video-assisted thoracoscopic surgery.

    Science.gov (United States)

    Terra, Ricardo Mingarini; Andrade, Juliano Ribeiro; Mariani, Alessandro Wasum; Garcia, Rodrigo Gobbo; Succi, Jose Ernesto; Soares, Andrey; Zimmer, Paulo Marcelo

    2016-01-01

    The concept of a hybrid operating room represents the union of a high-complexity surgical apparatus with state-of-the-art radiological tools (ultrasound, CT, fluoroscopy, or magnetic resonance imaging), in order to perform highly effective, minimally invasive procedures. Although the use of a hybrid operating room is well established in specialties such as neurosurgery and cardiovascular surgery, it has rarely been explored in thoracic surgery. Our objective was to discuss the possible applications of this technology in thoracic surgery, through the reporting of three cases. RESUMO O conceito de sala híbrida traduz a união de um aparato cirúrgico de alta complexidade com recursos radiológicos de última geração (ultrassom, TC, radioscopia e/ou ressonância magnética), visando a realização de procedimentos minimamente invasivos e altamente eficazes. Apesar de bem estabelecido em outras especialidades, como neurocirurgia e cirurgia cardiovascular, o uso da sala hibrida ainda é pouco explorado na cirurgia torácica. Nosso objetivo foi discutir as aplicações e as possibilidades abertas por essa tecnologia na cirurgia torácica através do relato de três casos.

  18. Protection of existing legal positions and procedural succession in operation plan procedures under German mining law. Remarks on the BVerwG decision of December 13, 1991 - 7C 25. 90. Bestandsschutz und Verfahrensstufung im Betriebsplanverfahren. Bemerkungen zum Urteil des BVerwG vom 13. 12. 1991 - 7C 25. 90

    Energy Technology Data Exchange (ETDEWEB)

    Kuehne, G.

    1992-06-01

    The author analyses a judgment of the German Federal Administrative Court that contains fundamental statements on operation plan procedures under German minin law. These statements centre on the meaning and function of framework operation plans, in particular their binding effect upon the authorities with respect to the subsequent principal and special operation plan procedures, and on the protection of existing legal positions in favour of the operator. The ruling moreover upholds the protection of third parties, even in favour of persons external to the operations. The author questions the statements of the Court with regard to its understanding of operation plan procedures in general and framework operation plan procedures in particular. He takes the view that they fail to appreciate the structural bipolarity of the legal relationship between the operator and the authority created by the operation plan permission. The main points of the judgment are published in UPR ('Umwelt- und Planungsrecht', a legal journal) 6/92, p. 236. (orig./HSCH).

  19. Miniaturized and Ferrite Based Tunable Bandpass Filters in LCP and LTCC Technologies for SoP Applications

    KAUST Repository

    Arabi, Eyad A.

    2015-04-01

    Wireless systems with emerging applications are leaning towards small size, light-weight and low cost. Another trend for these wireless devices is that new applications and functionalities are being added without increasing the size of the device. To accomplish this, individual components must be miniaturized and the system should be designed to maximize the integration of the individual components. The high level of 3D integration feasible in system on package design (SoP) concept can fulfill the latter requirement. Bandpass filters are important components on all wireless systems to reject the unwanted signals and reduce interference. Being mostly implemented with passive and distributed components, bandpass filters take considerable space in a wireless system. Moreover, with emerging bands and multiple applications encompassed in a single device, many bandpass filters are required. The miniaturization related to bandpass filters can be approached by three main ways: (1) at the component level through the miniaturization of individual bandpass filters, (2) at the system level through the use of tunable filters to reduce the overall number of filters, and (3) at the system level through the high level of integration in a 3D SoP platform. In this work we have focused on all three aspects of miniaturization of band pass filters mentioned above. In the first part of this work, a low frequency (1.5 GHz global positioning system (GPS) band) filter implemented through 3D lumped components in two leading SoP technologies, namely low temperature co-fired ceramic (LTCC) and the liquid crystal polymers (LCP) is demonstrated. The miniaturized filter is based on a second order topology, which has been modified to improve the selectivity and out-of-band rejection without increasing the size. Moreover, for the case of LCP, the filter is realized in an ultra-thin stack up comprising four metallization layers with an overall thickness of only 100 _m. Due to its ultra

  20. Dropwindsonde observations of the mean boundary layer structure in the low-latitude Pacific during SOP-1

    Science.gov (United States)

    Firestone, James K.

    1986-01-01

    The low-level mean thermodynamic and wind profiles in the transition between the trade winds and the ICZ are described using the FGGE level II-b dropwindsonde data set collected during the period of SOP-1 (January 15-February 20, 1979). The results illustrate the influence of decaying midlatitude frontal systems in the northwesternmost region, the general tradelike nature of the eastern regions, and the highly convective nature of a region near the equator. Contrary to the results obtained with the traditional approach to the tropical boundary layer, the FGGE data indicate a trade inversion that remains quasi-horizontal in the north-south direction despite an equatorward decrease in its frequency of occurrence, indicating that subsidence may be more important in equatorial regions than was previously thought.

  1. Reply [to: Atlantic Tropical Cyclogenetic Processes during SOP-3 NAMMA in the GEOS-5 Global Data Assimilation and Forecast System

    Science.gov (United States)

    Reale, Oreste; Lau, William K.

    2010-01-01

    This article is a Reply to a Comment by Scott Braun on a previously published article by O. Reale, K.-M. Lau, and E. Brin: "Atlantic tropical cyclogenetic processes during SOP-3 NAMMA in the GEOS-5 global data assimilation and forecast system", by Reale, Lau and Brin, hereafter referred to as RA09. RA09 investigated the role of the Saharan Air Layer (SAL) in tropical cyclogenetic processes associated with a non-developing easterly wave observed during the Special Observation Period (SOP-3) phase of the 2006 NASA African Monsoon Multidisciplinary Analyses (MAMMA). The wave was chosen because both interact heavily with Saharan air. Results showed: a) very steep moisture gradients are associated with the SAL in forecasts and analyses even at great distance from the Sahara; b) a thermal dipole (warm above, cool below) in the non-developing case. RA09A suggested that radiative effect of dust may play some role in producing a thermal structure less favorable to cyclogenesis, and also indicated that only global horizontal resolutions on the order of 20-30 kilometers can capture the large-scale transport and the fine thermal structure of the SAL Braun (2010) questions those results attributing the wave dissipation to midlatitude air. The core discussion is on a dry filament preceding the wave, on the presence of dust, and on the origin of the air contained in this dry filament. In the 'Reply', higher resolution analyses than the ones used by Braun, taken at almost coincident times with Aqua and Terra passes, are shown, to emphasize how the channel of dry air associated with W1 is indeed rich in dust. Backtrajectories on a higher resolution grid are also performed, leading to results drastically different from Braun (2010), and in particularly showing that there is a clear contribution of Saharan air. Finally, the 'Reply' presents evidence on that analyses at a horizontal resolution of one degree are inadequate to investigate such feature.

  2. Blind, fast and SOP independent polarization recovery for square dual polarization-MQAM formats and optical coherent receivers.

    Science.gov (United States)

    Chagnon, Mathieu; Osman, Mohamed; Xu, Xian; Zhuge, Qunbi; Plant, David V

    2012-12-03

    We present both theoretically and experimentally a novel blind and fast method for estimating the State of Polarization (SOP) of a single carrier channel modulated in square Dual Polarization (DP) MQAM format for optical coherent receivers. The method can be used on system startup, for quick channel reconfiguration, or for burst mode receivers. It consists of converting the received waveform from Jones to Stokes space and looping over an algorithm until a unitary polarization derotation matrix is estimated. The matrix is then used to initialize the center taps of the subsequent classical decision-directed stochastic gradient algorithm (DD-LMS). We present experimental comparisons of the initial Bit Error Rate (BER) and the speed of convergence of this blind Stokes space polarization recovery (PR) technique against the common Constant Modulus Algorithm (CMA). We demonstrate that this technique works on any square DP-MQAM format by presenting experimental results for DP-4QAM, -16QAM and -64QAM at varying distances and baud rates. We additionally numerically assess the technique for varying differential group delays (DGD) and sampling offsets on 28 Gbaud DP-4QAM format and show fast polarization recovery for instantaneous DGD as high as 90% of symbol duration. We show that the convergence time of this blind PR technique does not depend on the initial SOP as CMA does and allows switching to DD-LMS faster by more than an order of magnitude. For DP-4QAM, it shows a convergence time of 5.9 ns, which is much smaller than the convergence time of recent techniques using modified CMA algorithms for quicker convergence. BER of the first 20 × 10(3) symbols is always smaller by several factors for DP-16QAM and -64QAM but not always for DP-4QAM.

  3. A Probe into the Operation of Judicial Mechanism without Bureaucratic Administrative Procedure%审判权运行机制去行政化路径探索

    Institute of Scientific and Technical Information of China (English)

    杨方程; 沈成燕

    2015-01-01

    The reform of the operation of the judicial mechanism is the focus of a new round of judicial re-form in China.Currently,the administration of the operation of judicial mechanism refers mainly to the adminis-trative examination and approval system for the judicial cases,the administration of the status of the judge,the administration of the relationship between the upper court and the lower one,and the like.The bureaucratic ad-ministrative procedure of the operation of judicial mechanism has reduced the trial efficiency,and affected the in-dependent exercise of judicial power by the judge.It is not conducive to the realization of justice,and not condu-cive to the building of a healthy relationship between trial and supervision.As a result,it will lead to the situa-tion in which “those who render a final decision will not hear the case,and those who hear the case will have no right to judge”.To realize the operation of judicial mechanism without the interference from administrative proce-dure challenges the reform in four aspects:the change of traditional concept,and the raising of the consciousness of “removing bureaucratic administrative procedure”;the perfection of the judicial operation mechanism;the conducting of independent and impartial judicial supervision under the condition of maintaining open justice as a means;and the completion of supporting measures so as to restrict and safeguard the independence of judges.%审判权运行机制改革是我国新一轮司法改革的重点。当前审判权运行机制行政化主要表现在案件审批制度行政化、法官地位行政化、上下级法院关系行政化等方面。审判权运行机制行政化降低了审判效率、影响法官独立行使审判权、不利于司法公正的实现、不利于构建健康的审级监督关系,造成“作出裁判的人不审理案件,审理案件的人无权裁判”。审判权运行机制去行政化要着力于转变思想观念,提高“去

  4. Implementation of an error-reporting module within a biorepository IT application to enhance operations.

    Science.gov (United States)

    Wiles, Kerry R; Washington, M K

    2014-12-01

    The Collaborative (formerly the Cooperative) Human Tissue Network (CHTN) is a federally funded service oriented grant that provides high-quality biospecimens and services to the research community. The CHTN consists of six institutions located throughout the United States to assist investigators in obtaining research specimens required for basic research. The CHTN divisions have similar operating goals: however, each division is responsible for maintaining operations at their local institutions. This requires the divisions to identify ways to maintain and sustain operations in a challenging federally funded environment, especially when the number of investigators requesting services drives the operation. Sustainability plans and goals are often times patched together out of necessity rather than taking a thoughtful approach by clearly defining and aligning activities with business strategy and priorities. The CHTN Western Division at Vanderbilt University Medical Center (CHTN-WD) has responded to this challenge of biospecimen resource sustainability in the face of diminished funding by continually identifying ways to innovate our processes through IT enhancements and requiring that the innovation produce measurable and relevant criteria for credibly reporting our operations progress and performance issues. With these overarching goals in mind, CHTN-WD underwent a Lean Six Sigma (LSS) series to identify operational inefficiencies that could be addressed with redesigning workflow and innovating the processes using IT solutions. The result of this internal collaborative innovation process was the implementation of an error-reporting module (ERM) hosted within our biorepository donor IT application, which allowed staff to report errors immediately; determine the operational area responsible; assess the severity of the error; determine course of action; determine if standard operating procedure (SOPs) revisions were required; and through automated e-mails, alert the

  5. Implementation of an Error-Reporting Module Within a Biorepository IT Application to Enhance Operations

    Science.gov (United States)

    Washington, M.K.

    2014-01-01

    The Collaborative (formerly the Cooperative) Human Tissue Network (CHTN) is a federally funded service oriented grant that provides high-quality biospecimens and services to the research community. The CHTN consists of six institutions located throughout the United States to assist investigators in obtaining research specimens required for basic research. The CHTN divisions have similar operating goals: however, each division is responsible for maintaining operations at their local institutions. This requires the divisions to identify ways to maintain and sustain operations in a challenging federally funded environment, especially when the number of investigators requesting services drives the operation. Sustainability plans and goals are often times patched together out of necessity rather than taking a thoughtful approach by clearly defining and aligning activities with business strategy and priorities. The CHTN Western Division at Vanderbilt University Medical Center (CHTN-WD) has responded to this challenge of biospecimen resource sustainability in the face of diminished funding by continually identifying ways to innovate our processes through IT enhancements and requiring that the innovation produce measurable and relevant criteria for credibly reporting our operations progress and performance issues. With these overarching goals in mind, CHTN-WD underwent a Lean Six Sigma (LSS) series to identify operational inefficiencies that could be addressed with redesigning workflow and innovating the processes using IT solutions. The result of this internal collaborative innovation process was the implementation of an error-reporting module (ERM) hosted within our biorepository donor IT application, which allowed staff to report errors immediately; determine the operational area responsible; assess the severity of the error; determine course of action; determine if standard operating procedure (SOPs) revisions were required; and through automated e-mails, alert the

  6. Low level exposure to sulfur mustard: Development of an SOP for analysis of albumin adducts

    NARCIS (Netherlands)

    Noort, D.; Fidder, A.; Kant, S. de; Hulst, A.G.

    2004-01-01

    The need for retrospective detection procedures for exposure to low levels of chemical warfare agents has been urgently illustrated by the conflicts in the Gulf Area. Furthermore, in the case of a terrorist attack with CWA, rapid and reliable diagnosis of the exposure is essential. The present resea

  7. Progress of SOP Integration Technology and its Application in Millimeter-wave Systems%SOP集成技术的发展现状及其在毫米波系统中的应用*

    Institute of Scientific and Technical Information of China (English)

    朱勇; 张凯

    2013-01-01

      介绍了SOP(System-On-Package)集成技术,并与传统系统集成方法以及SOC(System-On-Chip)、MIP(Module-In-Package)、MCM(Multi-Chip-Module)、SIP(System-In-Package)等微封装、微集成技术进行了比较和分析,揭示了SOP小型化、低成本、高可靠性、高性能特点。对SOP在毫米波系统应用、新材料和新工艺的进展进行了总结,结果表明SOP在毫米波系统中具有良好的应用前景。%In this paper,System-On-Package(SOP)is introduced. SOP is compared with traditional system inte-gration technology and other types of integration technology,such as System-On-Chip(SOC),Module-In-Package (MIP),Multi-Chip-Module(MCM)and System-In-Package(SIP).On this base,it is illustrated that SOP is fea-tured by miniaturization,low cost,high reliability and high performance. And the progress of SOP in millimeter-wave system application,new material and new manufacture technology is analyzed. The results show that SOP has promising future in millimeter-wave systems.

  8. Antiarrhythnic effect of saponines of leaf of sophoridine, (Sop)%槐定碱抗心律失常作用的实验研究

    Institute of Scientific and Technical Information of China (English)

    谢世荣; 黄彩云; 黄胜英

    2002-01-01

    槐定碱(Sophoridine,Sop)10mg/kg、20mg/kg能明显对抗乌头碱20μg/kg,VaCl2和结扎左冠状动脉前降支诱发大鼠的室性心律失常.Sop也能明显对抗CaCl2-Ach(CaCl20.6%+Ach 0.0025%)混合液诱发小鼠心房纤颤或扑动.Sop 10mg/kg对大鼠心电图实验,证明有负性频率作用,负性传导作用.这些作用可能是Sop抗心律失常作用的药理基础.

  9. A case method for Sales and Operations Planning: a learning experience from Germany

    Directory of Open Access Journals (Sweden)

    Luiz Felipe Scavarda

    Full Text Available Abstract Adequate preparation, learning, and training is required for Sales and Operations Planning (S&OP to aid organizations in achieving the full expected benefits from its implementation. This paper presents a case method for S&OP and the learning experience of its application at the University of Münster (Germany. The “constructive alignment principle” was applied with a “team teaching” approach, involving an executive from the case company. Students improved their knowledge on S&OP and their analytical skills by understanding the conceptual S&OP building blocks and by learning how to deal with them to provide a solution for a case based on a real-life situation. The learning results were evaluated positively during the discipline’s student evaluation of teaching (SET. The applied case method enhanced the student’s motivation and engagement (e.g., higher preparation effort and class attendance, which were considered higher than in other disciplines with the traditional lecture-based education.

  10. ISHIKAWA ITERATION PROCEDURES WITH ERRORS FOR CERTAIN NONLINEAR OPERATOR WITHOUT LIPSCHITZ ASSUMPTION%一类无Lipschitz假设的非线性算子的带误差的Ishikawa迭代程序

    Institute of Scientific and Technical Information of China (English)

    倪仁兴; 叶新涛

    2001-01-01

    Several more general results on the convergence of the Ishikawa iteration procedures with errors for ψ-strong pseudo-contractions and nonlinear operator equations of ψ-strongly accretive type without Lipschitz assumption in Banach spaces are established, as the direct applications, some stability results of the Ishikawa iteration methods for ψ-strong pseudocontractions and nonlinear operator equations of ψ-strongly accretive type are also given. They unify, improve and extend the recent corresponding results.

  11. Maintenance and operation procedure, and feedback controls of the J-PARC RF-driven H{sup −} ion source

    Energy Technology Data Exchange (ETDEWEB)

    Ueno, A., E-mail: akira.ueno@j-parc.jp; Ohkoshi, K.; Ikegami, K.; Takagi, A.; Yamazaki, S.; Oguri, H. [J-PARC Center, Tokai-mura, Naka-gun, Ibaraki-ken 319-1195 (Japan)

    2015-04-08

    In order to satisfy the Japan Proton Accelerator Research Complex (J-PARC) second stage requirements of an H{sup −} ion beam of 60mA within normalized emittances of 1.5πmm•mrad both horizontally and vertically, a flat top beam duty factor of 1.25% (500μs×25Hz) and a life-time of longer than 1month, the J-PARC cesiated RF-driven H{sup −} ion source was developed by using an internal-antenna developed at the Spallation Neutron Source (SNS). The maintenance and operation procedure to minimize the plasma chamber (PCH) replacement time on the beam line, which is very important to maximize the J-PARC beam time especially for an antenna failure, is presented in this paper. The PCH preserved by filling argon (Ar) gas inside after pre-conditioning including pre-cesiation to produce the required beam at a test-stand successfully produced the required beam on the beam line with slight addition of cesium (Cs). The methods of the feedback controls of a 2MHz-RF-matching, an H{sup −} ion beam intensity and the addition of Cs are also presented. The RF-matching feedback by using two vacuum variable capacitors (VVCs) and RF-frequency shift produced the almost perfect matching with negligibly small reflected RF-power. The H{sup −} ion beam intensity was controlled within errors of ±0.1mA by the RF-power feedback. The amount of Cs was also controlled by remotely opening a Cs-valve to keep the RF-power lower than a settled value.

  12. World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonization Project: III. Fluid biospecimen collection, processing, and storage in endometriosis research

    DEFF Research Database (Denmark)

    Rahmioglu, Nilufer; Fassbender, Amelie; Vitonis, Allison F.;

    2014-01-01

    ObjectiveTo harmonize standard operating procedures (SOPs) and standardize the recording of associated data for collection, processing, and storage of fluid biospecimens relevant to endometriosis.......ObjectiveTo harmonize standard operating procedures (SOPs) and standardize the recording of associated data for collection, processing, and storage of fluid biospecimens relevant to endometriosis....

  13. World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonisation Project: IV. Tissue collection, processing, and storage in endometriosis research

    DEFF Research Database (Denmark)

    Fassbender, Amelie; Rahmioglu, Nilufer; Vitonis, Allison F.;

    2014-01-01

    ObjectiveTo harmonize standard operating procedures (SOPs) and standardize the recording of associated data for collection, processing, and storage of human tissues relevant to endometriosis.......ObjectiveTo harmonize standard operating procedures (SOPs) and standardize the recording of associated data for collection, processing, and storage of human tissues relevant to endometriosis....

  14. The Vocational-Technical Resource Consortia Serving Business and Industry in Ohio. Digest of Study: Operational Procedures for Successful Vocational-Technical Resource Consortia in Serving Business and Industry in Ohio.

    Science.gov (United States)

    Frasier, James E.; Stanton, William

    This publication reports the development of the vocational-technical resource consortia in Ohio and identifies the operational procedures associated with successful programs. Five exemplary consortia were studied in some depth; however, data were obtained from all of the 23 consortia in the state. The research indicates that the consortium is an…

  15. Prevalencia de Neospora caninum y DVB en una finca con problemas reproductivos en Sopó (Cundinamarca

    Directory of Open Access Journals (Sweden)

    John Fredy García-Chaparro

    2015-04-01

    Full Text Available La investigación tuvo como objetivo determinar la prevalencia de Neospora caninum y del virus de la diarrea viral bovina (DVB en bovinos de una finca con problemas reproductivos, en el municipio de Sopó (Cundinamarca, y su relación con la presentación de abortos. Se tomaron muestras de suero sanguíneo de 397 animales de alta producción lechera y con antecedentes reproductivos, seleccionados al azar.Se utilizó la inmunofluoresencia indirecta para la N. caninum, y seroneutralización para DVB, y los procedimientos se realizaron en el Laboratorio de Enfermedades Infecciosas de la Universidad de Parma (Italia. Se encontró una prevalencia de 10.37% para DVB con respecto a 21.26% para N. caninum, y estadísticamente no hubo relación directa con respecto a los problemas reproductivos. De acuerdo con los resultados obtenidos, se reportó mayor presencia significativa de N. caninum con relación a la de DVB en el hato lechero objeto de estudio.

  16. Multi-sensor analysis of convective activity in Central Italy during the HyMeX SOP 1.1

    Directory of Open Access Journals (Sweden)

    N. Roberto

    2015-09-01

    Full Text Available A multi-sensor analysis of convective precipitation events that occurred in central Italy, in autumn 2012 during the HyMeX (Hydrological cycle in the Mediterranean eXperiment Special Observation Period (SOP 1.1 is presented. Various microphysical properties of liquid and solid hydrometeors were examined to assess their relationship with lightning activity. The instrumentation used consisted of a C-band dual-polarization weather radar, a 2-D video disdrometer, and a lightning network. A fuzzy logic based hydrometeor classification algorithm was tuned and optimized for the detection of graupel from C-band dual-polarization radar measurements. Graupel ice water content was then retrieved and related to lightning activity. A linear correlation was found between the total mass of graupel above the 0° isothermal and the number of strokes detected by the lightning network in agreement with model outputs, which confirms the importance of ice in the electrical charging of convective clouds, although differences were noticed among events. Parameters of the gamma raindrop size distribution measured by a 2-D video disdrometer, revealed the transition from convective to stratiform regime during the event and where related. However, lightning activity was not always recorded when the precipitation regime was classified as convective. More robust relationships were found relating lightning activity to graupel.

  17. Tunable bandpass filter based on partially magnetized ferrite LTCC with embedded windings for SoP applications

    KAUST Repository

    Arabi, Eyad A.

    2015-01-01

    Tunable filters that are based on ferrite materials often require large and bulky electromagnets. In this work, we present a tunable filter in the Ku-band, which is realized in multilayer ferrite LTCC substrate with embedded bias windings, thus negating the need of a large electromagnet. Also, because of the embedded windings, the bias fields are not lost at the air-substrate interface and therefore the field and current requirements are reduced by an order of magnitude as compared to the previously reported filters. A simulation strategy that uses full permeability tensor with arbitrarily directed magnetic fields has been used to model the filter on a partially magnetized ferrite substrate. Special attention has also been paid to approximate the non-uniform magneto-static fields produced by the embedded windings. The complete design is implemented in 10 layers of ferrite LTCC, making it the first magnetically tunable filter with embedded windings and extremely small size [(5 × 5 × 1.1)mm3]. The filter demonstrates a measured tunability of 4% and an insertion loss of 2.3 dB. With the small form factor, embedded windings, and low bias requirements, the design is highly suitable for compact and tunable SoP applications.

  18. Observational and modeling study of a mesoscale convective system during the HyMeX - SOP1

    Science.gov (United States)

    Dafis, S.; Lagouvardos, K.; Kotroni, V.; Giannaros, T. M.; Bartzokas, A.

    2017-05-01

    An intense and fast moving convective line that crossed Massif Central/Cévennes-Vivarais area (south France) during the field campaign of Hydrological Cycle in Mediterranean Experiment (HyMeX) - Special Observing Period 1 (SOP1) is examined. The mesoscale analysis demonstrates a complex convective system with a V-shape in the Infrared (IR) satellite imagery and a squall line pattern on the radar imagery. Ground stations observed up to 60 mm h- 1 of rain accumulation, while the lightning activity, as observed by 4 detection networks, was also exceptionally high. The Weather Research and Forecasting (WRF) model was used to simulate this convective episode and sensitivity tests were performed with various microphysics and convective parameterization schemes. Satellite data from Meteosat SEVIRI Rapid Scanning Service were used in conjunction with radar, lightning and rain gauge data to conclude on the best simulation for which WRF model exhibits a rather precise and realistic distribution and evolution of the precipitation patterns. Finally, a study of the microphysics was performed indicating the interconnection of graupel with lightning activity, confirming recent results, compared against a sophisticated hydrometeor classification radar algorithm and lightning data.

  19. Proximate composition and selected physicochemical properties of the seed, pulp and oil of sour sop (Annona muricata).

    Science.gov (United States)

    Onimawo, I A

    2002-01-01

    Proximate composition and physicochemical analyses were carried out on the seed, pulp and extracted oil of sour sop (Annona muricata). The results showed that the seed contained 8.5% moisture, 2.4% crude protein, 13.6% ash, 8.0% crude fiber, 20.5% fat and 47.0% carbohydrate. The seed also contained 0.2% water soluble ash, 0.79% titratable acidity and 17.0 mg calcium/100 g. The pulp was found to contain 81% moisture, 3.43% titratable acidity and 24.5% non-reducing sugar. Selected physicochemical characteristics included refractive indices of 1.335 for the seed and 1.356 for the pulp, specific gravities of 1.250 for the seed and 1.023 for the pulp, pH values of 8.34 for the seed and 4.56 for the pulp, and soluble solids contents of 1.5 degrees Brix for the seed and 15 degrees Brix for the pulp. The extracted oil (20.5% yield) had a 60.43% unsaponifiable value, 23.54 KOH/g acid value, 100.98 KOH/g saponification value, 1.1 KOH/g peroxide value, 1.464 refractive index, 5.77 pH, 69.5 degrees Brix sosluble solids and 0.2900 specific gravity.

  20. [Helsinki Declaration on Patient Safety in Anaesthesiology--Part 8: SOP for checking equipment and drugs].

    Science.gov (United States)

    Happel, Oliver; Roewer, Norbert; Kranke, Peter

    2013-09-01

    In 2010 the Helsinki Declaration on Patient Safety in Anaesthesiology was launched. In this joined statement under the auspice of the European Society of Anaesthesiology the need for protocols for different aspects of perioperative procedures that could affect patient safety was stated. All participating institutions should have--among others--protocols for checking equipment and drugs required for the delivery of safe anaesthesia. The background for this being the fact that the lack of carefully checking equipment and drugs--or not adhering to existing checklists--is a latent threat to patient safety and thus may increase morbidity and mortality.In this part of a series the authors present protocols existing in their clinic for checking anaesthesia equipment and drugs.