WorldWideScience

Sample records for open research field

  1. Open-Access, Low-Magnetic-Field MRI System for Lung Research

    Science.gov (United States)

    Mair, Ross W.; Rosen, Matthew S.; Tsai, Leo L.; Walsworth, Ronald L.; Hrovat, Mirko I.; Patz, Samuel; Ruset, Iullian C.; Hersman, F. William

    2009-01-01

    An open-access magnetic resonance imaging (MRI) system is being developed for use in research on orientational/gravitational effects on lung physiology and function. The open-access geometry enables study of human subjects in diverse orientations. This system operates at a magnetic flux density, considerably smaller than the flux densities of typical other MRI systems, that can be generated by resistive electromagnet coils (instead of the more-expensive superconducting coils of the other systems). The human subject inhales air containing He-3 or Xe-129 atoms, the nuclear spins of which have been polarized by use of a laser beam to obtain a magnetic resonance that enables high-resolution gas space imaging at the low applied magnetic field. The system includes a bi-planar, constant-current, four-coil electromagnet assembly and associated electronic circuitry to apply a static magnetic field of 6.5 mT throughout the lung volume; planar coils and associated circuitry to apply a pulsed magnetic-field-gradient for each spatial dimension; a single, detachable radio-frequency coil and associated circuitry for inducing and detecting MRI signals; a table for supporting a horizontal subject; and electromagnetic shielding surrounding the electromagnet coils.

  2. Open Access, Education Research, and Discovery

    Science.gov (United States)

    Furlough, Michael

    2010-01-01

    Background/Context: The open access movement has successfully drawn attention to economic and political aspects of scholarly communication through a significant body of commentary that debates the merits of open access and the potential damage it may do to scholarly publishing. Researchers within the field of education research, notably John…

  3. Can Polar Fields Explain Missing Open Flux?

    Science.gov (United States)

    Linker, J.; Downs, C.; Caplan, R. M.; Riley, P.; Mikic, Z.; Lionello, R.

    2017-12-01

    The "open" magnetic field is the portion of the Sun's magnetic field that extends out into the heliosphere and becomes the interplanetary magnetic field (IMF). Both the IMF and the Sun's magnetic field in the photosphere have been measured for many years. In the standard paradigm of coronal structure, the open magnetic field originates primarily in coronal holes. The regions that are magnetically closed trap the coronal plasma and give rise to the streamer belt. This basic picture is qualitatively reproduced by models of coronal structure using photospheric magnetic fields as input. If this paradigm is correct, there are two primary observational constraints on the models: (1) The open field regions in the model should approximately correspond to coronal holes observed in emission, and (2) the magnitude of the open magnetic flux in the model should match that inferred from in situ spacecraft measurements. Linker et al. (2017, ApJ, submitted) investigated the July 2010 time period for a range of observatory maps and both PFSS and MHD models. We found that all of the model/map combinations underestimated the interplanetary magnetic flux, unless the modeled open field regions were larger than observed coronal holes. An estimate of the open magnetic flux made entirely from solar observations (combining detected coronal hole boundaries with observatory synoptic magnetic maps) also underestimated the interplanetary magnetic flux. The magnetic field near the Sun's poles is poorly observed and may not be well represented in observatory maps. In this paper, we explore whether an underestimate of the polar magnetic flux during this time period could account for the overall underestimate of open magnetic flux. Research supported by NASA, AFOSR, and NSF.

  4. Open Access Publishing in the Field of Medical Informatics.

    Science.gov (United States)

    Kuballa, Stefanie

    2017-05-01

    The open access paradigm has become an important approach in today's information and communication society. Funders and governments in different countries stipulate open access publications of funded research results. Medical informatics as part of the science, technology and medicine disciplines benefits from many research funds, such as National Institutes of Health in the US, Wellcome Trust in UK, German Research Foundation in Germany and many more. In this study an overview of the current open access programs and conditions of major journals in the field of medical informatics is presented. It was investigated whether there are suitable options and how they are shaped. Therefore all journals in Thomson Reuters Web of Science that were listed in the subject category "Medical Informatics" in 2014 were examined. An Internet research was conducted by investigating the journals' websites. It was reviewed whether journals offer an open access option with a subsequent check of conditions as for example the type of open access, the fees and the licensing. As a result all journals in the field of medical informatics that had an impact factor in 2014 offer an open access option. A predominantly consistent pricing range was determined with an average fee of 2.248 € and a median fee of 2.207 €. The height of a journals' open access fee did not correlate with the height of its Impact Factor. Hence, medical informatics journals have recognized the trend of open access publishing, though the vast majority of them are working with the hybrid method. Hybrid open access may however lead to problems in questions of double dipping and the often stipulated gold open access.

  5. Does open-field exposure during infancy influence open-field behavior of the same adult mice?

    OpenAIRE

    Vidal Gómez, José

    2013-01-01

    The goal of this report is to find out whether early exposure of mice to the open-field results in altered behavior of the same adult mice in the same open-field. Early exposure to the open-field was carried out between birth and weaning; two control groups were included: control 2 (mice exposed to a reduced dark space) and control 1 (mice left undisturbed). The (male and female) mice were of the Balb/c and C57Bl/6 strains. Adult C57Bl/6 female mice of the openfield and control 2 groups ambul...

  6. Open life science research, open software and the open century

    Directory of Open Access Journals (Sweden)

    Youhua Chen

    2015-05-01

    Full Text Available At the age of knowledge explosion and mass scientific information, I highlighted the importance of conducting open science in life and medical researches through the extensive usage of open software and documents. The proposal of conducting open science is to reduce the limited repeatability of researches in life science. I outlined the essential steps for conducting open life science and the necessary standards for creating, reusing and reproducing open materials. Different Creative Commons licenses were presented and compared of their usage scope and restriction. As a conclusion, I argued that open materials should be widely adopted in doing life and medical researches.

  7. Openly Published Environmental Sensing (OPEnS) | Advancing Open-Source Research, Instrumentation, and Dissemination

    Science.gov (United States)

    Udell, C.; Selker, J. S.

    2017-12-01

    The increasing availability and functionality of Open-Source software and hardware along with 3D printing, low-cost electronics, and proliferation of open-access resources for learning rapid prototyping are contributing to fundamental transformations and new technologies in environmental sensing. These tools invite reevaluation of time-tested methodologies and devices toward more efficient, reusable, and inexpensive alternatives. Building upon Open-Source design facilitates community engagement and invites a Do-It-Together (DIT) collaborative framework for research where solutions to complex problems may be crowd-sourced. However, barriers persist that prevent researchers from taking advantage of the capabilities afforded by open-source software, hardware, and rapid prototyping. Some of these include: requisite technical skillsets, knowledge of equipment capabilities, identifying inexpensive sources for materials, money, space, and time. A university MAKER space staffed by engineering students to assist researchers is one proposed solution to overcome many of these obstacles. This presentation investigates the unique capabilities the USDA-funded Openly Published Environmental Sensing (OPEnS) Lab affords researchers, within Oregon State and internationally, and the unique functions these types of initiatives support at the intersection of MAKER spaces, Open-Source academic research, and open-access dissemination.

  8. Open-field test site

    Science.gov (United States)

    Gyoda, Koichi; Shinozuka, Takashi

    1995-06-01

    An open-field test site with measurement equipment, a turn table, antenna positioners, and measurement auxiliary equipment was remodelled at the CRL north-site. This paper introduces the configuration, specifications and characteristics of this new open-field test site. Measured 3-m and 10-m site attenuations are in good agreement with theoretical values, and this means that this site is suitable for using 3-m and 10-m method EMI/EMC measurements. The site is expected to be effective for antenna measurement, antenna calibration, and studies on EMI/EMC measurement methods.

  9. Thigmotactic responses in an open-field

    Directory of Open Access Journals (Sweden)

    M.R. Lamprea

    2008-02-01

    Full Text Available The goal of the present study was to investigate the role of thigmotaxis (the tendency to remain close to vertical surfaces in rat exploratory behavior in an open-field. Thigmotaxis was investigated in a parametric way, using 24 experimentally adult naive male Wistar rats (210-230 g. Exploratory behavior was studied in an open-field (N = 12 in 5-min sessions and behavior was analyzed in terms of where it occurred: in areas surrounded by two, one, or no walls. Another group of rats (N = 12 was studied in an open-field with blocks placed near two of the corners so as to make these corner areas surrounded by three walls. The floor of the open-fields was divided into 20-cm squares in order to locate the exact place of occurrence of each behavior. The following behaviors were recorded: entries into the squares, rearings, and groomings. In both types of open-field the rats chose to remain longer in the squares surrounded by the largest possible number of walls. In one of the open-fields, the mean time (seconds spent in squares surrounded by two walls was longer than the time spent in squares surrounded by one or no walls (37.2, 7.7, and 1.8 s, respectively. In the other open-field, the mean time spent in squares surrounded by three walls was longer than the time spent in squares surrounded by two, one or no walls (41.7, 20.4, 7.0, and 2.6 s, respectively. Other measures presented a similar profile. These results indicate that rats are sensitive to the number of walls in an environment and prefer to remain close to them.

  10. Open magnetic fields in active regions

    International Nuclear Information System (INIS)

    Svestka, Z.; Solodyna, C.V.; Levine, R.H.

    1977-01-01

    Soft X-ray observations confirm that some of the dark gaps seen between interconnecting loops and inner cores of active regions may be loci of open fields, as it has been predicted by global potential extrapolation of photospheric magnetic fields. It seems that the field lines may open only in a later state of the active region development. (Auth.)

  11. Hidden gravity in open-string field theory

    International Nuclear Information System (INIS)

    Siegel, W.

    1994-01-01

    We clarify the nature of the graviton as a bound state in open-string field theory: The flat metric in the action appears as the vacuum value of an open string field. The bound state appears as a composite field in the free field theory

  12. Forward Field Computation with OpenMEEG

    Directory of Open Access Journals (Sweden)

    Alexandre Gramfort

    2011-01-01

    must be computed. We present OpenMEEG, which solves the electromagnetic forward problem in the quasistatic regime, for head models with piecewise constant conductivity. The core of OpenMEEG consists of the symmetric Boundary Element Method, which is based on an extended Green Representation theorem. OpenMEEG is able to provide lead fields for four different electromagnetic forward problems: Electroencephalography (EEG, Magnetoencephalography (MEG, Electrical Impedance Tomography (EIT, and intracranial electric potentials (IPs. OpenMEEG is open source and multiplatform. It can be used from Python and Matlab in conjunction with toolboxes that solve the inverse problem; its integration within FieldTrip is operational since release 2.0.

  13. On multibrane solutions in open string field theory

    Czech Academy of Sciences Publication Activity Database

    Murata, Masaki; Schnabl, Martin

    2011-01-01

    Roč. 2011, č. 188 (2011), s. 50-55 ISSN 0375-9687. [International Conference on String Field Theory and Related Aspects (SFT2010). Kyoto, 18.10.2010-22.10.2010] Grant - others:EUROHORC and ESF(XE) EYI/07/E010 Institutional research plan: CEZ:AV0Z10100502 Keywords : string field theory * D-branes * open strings Subject RIV: BF - Elementary Particles and High Energy Physics Impact factor: 1.063, year: 2011 http://ptp.ipap.jp/link?PTPS/188/50/

  14. Structure and magnetic field of periodic permanent magnetic focusing system with open magnetic rings

    International Nuclear Information System (INIS)

    Peng Long; Li Lezhong; Yang Dingyu; Zhu Xinghua; Li Yuanxun

    2011-01-01

    The magnetic field along the central axis for an axially magnetized permanent magnetic ring was investigated by analytical and finite element methods. For open magnetic rings, both calculated and measured results show that the existence of the radial magnetic field creates a remarkable cosine distribution field along the central axis. A new structure of periodic permanent magnet focusing system with open magnetic rings is proposed. The structure provides a satisfactory magnetic field with a stable peak value of 120 mT for a traveling wave tube system. - Research highlights: → For open magnetic rings, both calculated and measured results show that the existence of the radial magnetic field creates a remarkable cosine distribution field along the central axis. → A new structure of periodic permanent magnet (PPM) focusing system with open magnetic rings is proposed. → The new PPM focusing system with open magnetic rings meets the requirements for TWT system.

  15. Standardized UXO Technology Demonstration Site Open Field Scoring Record Number 673 (Naval Research Laboratories)

    National Research Council Canada - National Science Library

    Overbay, Larry; Robitaille, George

    2005-01-01

    ...) utilizing the APG standardized UXO Technology Demonstration Site Open Field. Scoring Records have been coordinate by Larry Overbay and the Standardized UXO Technology Demonstration Site Scoring Committee...

  16. Standardized UXO Technology Demonstration Site Open Field Scoring Record No. 901 (Sky Research, Inc.)

    National Research Council Canada - National Science Library

    McClung, J. S; Fling, Rick; McClung, Christina; Burch, William; Lombardo, Leonardo; McDonnell, Patrick

    2008-01-01

    ...) utilizing the APG Standardized UXO Technology Demonstration Site Open Field. This Scoring Record was coordinated by Stephen McClung and the Standardized UXO Technology Demonstration Site Scoring Committee...

  17. Open magnetic fields in active regions

    Science.gov (United States)

    Svestka, Z.; Solodyna, C. V.; Howard, R.; Levine, R. H.

    1977-01-01

    Soft X-ray images and magnetograms of several active regions and coronal holes are examined which support the interpretation that some of the dark X-ray gaps seen between interconnecting loops and inner cores of active regions are foot points of open field lines inside the active regions. Characteristics of the investigated dark gaps are summarized. All the active regions with dark X-ray gaps at the proper place and with the correct polarity predicted by global potential extrapolation of photospheric magnetic fields are shown to be old active regions, indicating that field opening is accomplished only in a late phase of active-region development. It is noted that some of the observed dark gaps probably have nothing in common with open fields, but are either due to the decreased temperature in low-lying portions of interconnecting loops or are the roots of higher and less dense or cooler loops.

  18. Plasma behaviors in the open field region of reversed-field theta-pinch

    International Nuclear Information System (INIS)

    Aso, Yoshiyuki; Hirano, Keiichi.

    1983-03-01

    A characteristic behavior of the plasma in an open field region of reversed field theta pinch has been studied with the guide field (GF) which extends the field line along the axial direction. The experimental result suggests that the rotaional instability may be induced in FRC after the plasma touches the wall at the ends of the open field. (author)

  19. On background-independent open-string field theory

    International Nuclear Information System (INIS)

    Witten, E.

    1992-01-01

    A framework for background-independent open-string field theory is proposed. The approach involves using the Batalin-Vilkovisky formalism, in a way suggested by recent developments in closed-string field theory, to implicitly define a gauge-invariant Lagrangian in a hypothetical ''space of all open-string world-sheet theories.'' It is built into the formalism that classical solutions of the string field theory are Becchi-Rouet-Stora-Tyutin- (BRST-) invariant open-string world-sheet theories and that, when expanding around a classical solution, the infinitesimal gauge transformations are generated by the world-sheet BRST operator

  20. Open-closed string correspondence in open string field theory

    International Nuclear Information System (INIS)

    Baumgartl, M.; Sachs, I.

    2008-01-01

    We address the problem of describing different closed string backgrounds in background independent open string field theory: A shift in the closed string background corresponds to a collective excitation of open strings. As an illustration we apply the formalism to the case where the closed string background is a group manifold. (Abstract Copyright [2008], Wiley Periodicals, Inc.)

  1. Topological defects in open string field theory

    Science.gov (United States)

    Kojita, Toshiko; Maccaferri, Carlo; Masuda, Toru; Schnabl, Martin

    2018-04-01

    We show how conformal field theory topological defects can relate solutions of open string field theory for different boundary conditions. To this end we generalize the results of Graham and Watts to include the action of defects on boundary condition changing fields. Special care is devoted to the general case when nontrivial multiplicities arise upon defect action. Surprisingly the fusion algebra of defects is realized on open string fields only up to a (star algebra) isomorphism.

  2. Background Independent Open String Field Theory and Constant B-Field

    OpenAIRE

    Nemeschansky, D.; Yasnov, V.

    2000-01-01

    We calculate the background independent action for bosonic and supersymmetric open string field theory in a constant B-field. We also determine the tachyon effective action in the presence of constant B-field.

  3. Open-field exposure facilitates consummatory extinction.

    Science.gov (United States)

    Justel, Nadia; Psyrdellis, Mariana; Pautassi, Ricardo M

    2016-12-07

    During extinction, the organism learns that a conditioned stimulus or a conditioned response is no longer associated with an unconditioned stimulus, and as a consequence, a decrement in the response is presented. The exposure to novel situations (e.g. exploration of a novel open field) has been used widely to modulate (i.e. either enhance or deteriorate) learning and memory. The aim of the present study was to test whether open-field exposure could modulate consummatory extinction. The results indicated that open-field exposure accelerated the extinction response (i.e. experimental animals provided novelty exposure had lower consummatory behavior than control animals) when applied before - but not after - the first extinction trial, or when applied before the second extinction trial. The results suggest that environmental treatments such as novelty exposure provide a valuable, nonpharmacological alternative to potentially modulate extinction processes.

  4. Research progress on related genes for primary open angle glaucoma

    Directory of Open Access Journals (Sweden)

    Ailijiang·Aierken

    2014-04-01

    Full Text Available Primary open angle glaucoma(POAGis the main cause of blindness with visual field damage and optic nerve degeneration. In recent years, a lot of researches have been done, showing that genetic factors and gene mutation play an important role in POAG. There are more than 20 related POAG genes. Now we will review the related genes of POAG, especially the well known causative genes of MYOC, OPTN, WDR36, and CAV1/CAV2, in terms of their locations, structures, research progress, et al, and provide a reference for genetic research in primary open-angle glaucoma.

  5. How open science helps researchers succeed

    Science.gov (United States)

    McKiernan, Erin C; Bourne, Philip E; Brown, C Titus; Buck, Stuart; Kenall, Amye; Lin, Jennifer; McDougall, Damon; Nosek, Brian A; Ram, Karthik; Soderberg, Courtney K; Spies, Jeffrey R; Thaney, Kaitlin; Updegrove, Andrew; Woo, Kara H; Yarkoni, Tal

    2016-01-01

    Open access, open data, open source and other open scholarship practices are growing in popularity and necessity. However, widespread adoption of these practices has not yet been achieved. One reason is that researchers are uncertain about how sharing their work will affect their careers. We review literature demonstrating that open research is associated with increases in citations, media attention, potential collaborators, job opportunities and funding opportunities. These findings are evidence that open research practices bring significant benefits to researchers relative to more traditional closed practices. DOI: http://dx.doi.org/10.7554/eLife.16800.001 PMID:27387362

  6. Widening access through openness in higher education in the developing world: A Bourdieusian field analysis of experiences from the National Open University of Nigeria

    Directory of Open Access Journals (Sweden)

    Felix Kayode Olakulehin

    2013-01-01

    Full Text Available Bourdieu has argued that higher education is a field that reproduces social inequality, thus complicating how openness widens access to higher education in the developing world. Drawing on the experiences of the National Open University of Nigeria (NOUN, this paper critically analyses and evaluates the rationale, approach, difficulties, opportunities, outcomes and benefits of NOUN’s experience in widening access to higher education in Nigeria using Bourdieu’s field theory. We argue that the success of efforts for openness in higher education in a developing world context involves steering the contradictory tensions of openness and access across competing policy and practice fields. We offer this theorisation as a future social theoretical agenda for reflexive research for improving the effectiveness of praxis to widen access through openness in higher education in the developing world.

  7. Interdisciplinary research center devoted to molecular environmental science opens

    Science.gov (United States)

    Vaughan, David J.

    In October, a new research center opened at the University of Manchester in the United Kingdom. The center is the product of over a decade of ground-breaking interdisciplinary research in the Earth and related biological and chemical sciences at the university The center also responds to the British governments policy of investing in research infrastructure at key universities.The Williamson Research Centre, the first of its kind in Britain and among the first worldwide, is devoted to the emerging field of molecular environmental science. This field also aims to bring about a revolution in understanding of our environment. Though it may be a less violent revolution than some, perhaps, its potential is high for developments that could affect us all.

  8. FAIMS Mobile: Flexible, open-source software for field research

    Science.gov (United States)

    Ballsun-Stanton, Brian; Ross, Shawn A.; Sobotkova, Adela; Crook, Penny

    2018-01-01

    FAIMS Mobile is a native Android application supported by an Ubuntu server facilitating human-mediated field research across disciplines. It consists of 'core' Java and Ruby software providing a platform for data capture, which can be deeply customised using 'definition packets' consisting of XML documents (data schema and UI) and Beanshell scripts (automation). Definition packets can also be generated using an XML-based domain-specific language, making customisation easier. FAIMS Mobile includes features allowing rich and efficient data capture tailored to the needs of fieldwork. It also promotes synthetic research and improves transparency and reproducibility through the production of comprehensive datasets that can be mapped to vocabularies or ontologies as they are created.

  9. Open Content in Open Context

    Science.gov (United States)

    Kansa, Sarah Whitcher; Kansa, Eric C.

    2007-01-01

    This article presents the challenges and rewards of sharing research content through a discussion of Open Context, a new open access data publication system for field sciences and museum collections. Open Context is the first data repository of its kind, allowing self-publication of research data, community commentary through tagging, and clear…

  10. Shear-induced opening of the coronal magnetic field

    Science.gov (United States)

    Wolfson, Richard

    1995-01-01

    This work describes the evolution of a model solar corona in response to motions of the footpoints of its magnetic field. The mathematics involved is semianalytic, with the only numerical solution being that of an ordinary differential equation. This approach, while lacking the flexibility and physical details of full MHD simulations, allows for very rapid computation along with complete and rigorous exploration of the model's implications. We find that the model coronal field bulges upward, at first slowly and then more dramatically, in response to footpoint displacements. The energy in the field rises monotonically from that of the initial potential state, and the field configuration and energy appraoch asymptotically that of a fully open field. Concurrently, electric currents develop and concentrate into a current sheet as the limiting case of the open field is approached. Examination of the equations shows rigorously that in the asymptotic limit of the fully open field, the current layer becomes a true ideal MHD singularity.

  11. Open Drug Discovery Toolkit (ODDT): a new open-source player in the drug discovery field.

    Science.gov (United States)

    Wójcikowski, Maciej; Zielenkiewicz, Piotr; Siedlecki, Pawel

    2015-01-01

    There has been huge progress in the open cheminformatics field in both methods and software development. Unfortunately, there has been little effort to unite those methods and software into one package. We here describe the Open Drug Discovery Toolkit (ODDT), which aims to fulfill the need for comprehensive and open source drug discovery software. The Open Drug Discovery Toolkit was developed as a free and open source tool for both computer aided drug discovery (CADD) developers and researchers. ODDT reimplements many state-of-the-art methods, such as machine learning scoring functions (RF-Score and NNScore) and wraps other external software to ease the process of developing CADD pipelines. ODDT is an out-of-the-box solution designed to be easily customizable and extensible. Therefore, users are strongly encouraged to extend it and develop new methods. We here present three use cases for ODDT in common tasks in computer-aided drug discovery. Open Drug Discovery Toolkit is released on a permissive 3-clause BSD license for both academic and industrial use. ODDT's source code, additional examples and documentation are available on GitHub (https://github.com/oddt/oddt).

  12. Emotionality in growing pigs: is the open field a valid test?

    Science.gov (United States)

    Donald, Ramona D; Healy, Susan D; Lawrence, Alistair B; Rutherford, Kenneth M D

    2011-10-24

    The ability to assess emotionality is important within animal welfare research. Yet, for farm animals, few tests of emotionality have been well validated. Here we investigated the construct validity of behavioural measures of pig emotionality in an open-field test by manipulating the experiences of pigs in three ways. In Experiment One (pharmacological manipulation), pigs pre-treated with Azaperone, a drug used to reduce stress in commercial pigs, were more active, spent more time exploring and vocalised less than control pigs. In Experiment Two (social manipulation), pigs that experienced the open-field arena with a familiar companion were also more exploratory, spent less time behaviourally idle, and were less vocal than controls although to a lesser degree than in Experiment One. In Experiment Three (novelty manipulation), pigs experiencing the open field for a second time were less active, explored less and vocalised less than they had done in the first exposure to the arena. A principal component analysis was conducted on data from all three trials. The first two components could be interpreted as relating to the form (cautious to exploratory) and magnitude (low to high arousal) of the emotional response to open-field testing. Based on these dimensions, in Experiment One, Azaperone pigs appeared to be less fearful than saline-treated controls. However, in Experiment Two, exposure to the arena with a conspecific did not affect the first two dimensions but did affect a third behavioural dimension, relating to oro-nasal exploration of the arena floor. In Experiment Three, repeat exposure altered the form but not the magnitude of emotional response: pigs were less exploratory in the second test. In conclusion, behavioural measures taken from pigs in an open-field test are sensitive to manipulations of their prior experience in a manner that suggests they reflect underlying emotionality. Behavioural measures taken during open-field exposure can be useful for making

  13. Enabling cross-disciplinary research by linking data to Open Access publications

    Science.gov (United States)

    Rettberg, N.

    2012-04-01

    OpenAIREplus focuses on the linking of research data to associated publications. The interlinking of research objects has implications for optimising the research process, allowing the sharing, enrichment and reuse of data, and ultimately serving to make open data an essential part of first class research. The growing call for more concrete data management and sharing plans, apparent at funder and national level, is complemented by the increasing support for a scientific infrastructure that supports the seamless access to a range of research materials. This paper will describe the recently launched OpenAIREplus and will detail how it plans to achieve its goals of developing an Open Access participatory infrastructure for scientific information. OpenAIREplus extends the current collaborative OpenAIRE project, which provides European researchers with a service network for the deposit of peer-reviewed FP7 grant-funded Open Access publications. This new project will focus on opening up the infrastructure to data sources from subject-specific communities to provide metadata about research data and publications, facilitating the linking between these objects. The ability to link within a publication out to a citable database, or other research data material, is fairly innovative and this project will enable users to search, browse, view, and create relationships between different information objects. In this regard, OpenAIREplus will build on prototypes of so-called "Enhanced Publications", originally conceived in the DRIVER-II project. OpenAIREplus recognizes the importance of representing the context of publications and datasets, thus linking to resources about the authors, their affiliation, location, project data and funding. The project will explore how links between text-based publications and research data are managed in different scientific fields. This complements a previous study in OpenAIRE on current disciplinary practices and future needs for infrastructural

  14. Dimensions of open research: critical reflections on openness in the ROER4D project

    Directory of Open Access Journals (Sweden)

    Thomas William King

    2016-05-01

    Full Text Available Open Research has the potential to advance the scientific process by improving the transparency, rigour, scope and reach of research, but choosing to experiment with Open Research carries with it a set of ideological, legal, technical and operational considerations. Researchers, especially those in resource-constrained situations, may not be aware of the complex interrelations between these different domains of open practice, the additional resources required, or how Open Research can support traditional research practices. Using the Research on Open Educational Resources for Development (ROER4D project as an example, this paper attempts to demonstrate the interrelation between ideological, legal, technical and operational openness; the resources that conducting Open Research requires; and the benefits of an iterative, strategic approach to one’s own Open Research practice. In this paper we discuss the value of a critical approach towards Open Research to ensure better coherence between ‘open’ ideology (embodied in strategic intention and ‘open’ practice (the everyday operationalisation of open principles.

  15. Research advances on multifocal electroretinogram in primary open angle glaucoma

    Directory of Open Access Journals (Sweden)

    Feng-Fei Mo

    2013-10-01

    Full Text Available Primary open angle glaucoma is a chronic and progressive optic neuropathy. It can lead to serious damage of visual impairment, and it is an important eye disease of blindness. Multifocal electroretinogram is a new way to measure visual electrophysiology. It can measure electroretinogram of the whole visual field of many small parts in a relatively short period of time, and it can reflect the function of regional retina. It has an extremely important value for early diagnosis of primary open angle glaucoma. The research advances on multifocal electroretinogram in diagnosing primary open angle glaucoma were summarized in this paper.

  16. Habituation of medaka (Oryzias latipes) demonstrated by open-field testing.

    Science.gov (United States)

    Matsunaga, Wataru; Watanabe, Eiji

    2010-10-01

    Habituation to novel environments is frequently studied to analyze cognitive phenotypes in animals, and an open-field test is generally conducted to investigate the changes that occur in animals during habituation. The test has not been used in behavioral studies of medaka (Oryzias latipes), which is recently being used in behavioral research. Therefore, we examined the open-field behavior of medaka on the basis of temporal changes in 2 conventional indexes of locomotion and position. The findings of our study clearly showed that medaka changed its behavior through multiple temporal phases as it became more familiar with new surroundings; this finding is consistent with those of other ethological studies in animals. During repeated open-field testing on 2 consecutive days, we observed that horizontal locomotion on the second day was less than that on the first day, which suggested that habituation is retained in fish for days. This temporal habituation was critically affected by water factors or visual cues of the tank, thereby suggesting that fish have spatial memory of their surroundings. Thus, the data from this study will afford useful fundamental information for behavioral phenotyping of medaka and for elucidating cognitive phenotypes in animals. Copyright (c) 2010 Elsevier B.V. All rights reserved.

  17. The open innovation research landscape

    DEFF Research Database (Denmark)

    Bogers, Marcel; Zobel, Ann-Kristin; Afuah, Allan

    2017-01-01

    This paper provides an overview of the main perspectives and themes emerging in research on open innovation (OI). The paper is the result of a collaborative process among several OI scholars – having a common basis in the recurrent Professional Development Workshop on ‘Researching Open Innovation...

  18. On the helicity of open magnetic fields

    International Nuclear Information System (INIS)

    Prior, C.; Yeates, A. R.

    2014-01-01

    We reconsider the topological interpretation of magnetic helicity for magnetic fields in open domains, and relate this to the relative helicity. Specifically, our domains stretch between two parallel planes, and each of these ends may be magnetically open. It is demonstrated that, while the magnetic helicity is gauge-dependent, its value in any gauge may be physically interpreted as the average winding number among all pairs of field lines with respect to some orthonormal frame field. In fact, the choice of gauge is equivalent to the choice of reference field in the relative helicity, meaning that the magnetic helicity is no less physically meaningful. We prove that a particular gauge always measures the winding with respect to a fixed frame, and propose that this is normally the best choice. For periodic fields, this choice is equivalent to measuring relative helicity with respect to a potential reference field. However, for aperiodic fields, we show that the potential field can be twisted. We prove by construction that there always exists a possible untwisted reference field.

  19. A toy model for single field open inflation

    International Nuclear Information System (INIS)

    Vaudrevange, Pascal M.; Westphal, Alexander

    2012-05-01

    Inflation in an open universe produced by Coleman-De Luccia (CDL) tunneling induces a friction term that is strong enough to allow for successful small-field inflation in models that would otherwise suffer from a severe overshoot problem. In this paper, we present a polynomial scalar potential which allows for a full analysis. This provides a simple model of single-field open inflation on a small-field inflection point after tunneling. We present numerical results and compare them with analytic approximations.

  20. Open and Closed String field theory interpreted in classical Algebraic Topology

    OpenAIRE

    Sullivan, Dennis

    2003-01-01

    There is an interpretation of open string field theory in algebraic topology. An interpretation of closed string field theory can be deduced from this open string theory to obtain as well the interpretation of open and closed string field theory combined.

  1. Towards an Open Software Platform for Field Robots in Precision Agriculture

    DEFF Research Database (Denmark)

    Jensen, Kjeld; Larsen, Morten; Nielsen, Søren H

    2014-01-01

    Robotics in precision agriculture has the potential to improve competitiveness and increase sustainability compared to current crop production methods and has become an increasingly active area of research. Tractor guidance systems for supervised navigation and implement control have reached...... the market, and prototypes of field robots performing precision agriculture tasks without human intervention also exist. But research in advanced cognitive perception and behaviour that is required to enable a more efficient, reliable and safe autonomy becomes increasingly demanding due to the growing...... software complexity. A lack of collaboration between research groups contributes to the problem. Scientific publications describe methods and results from the work, but little field robot software is released and documented for others to use. We hypothesize that a common open software platform tailored...

  2. Open Field Scoring Record No. 298

    National Research Council Canada - National Science Library

    Overbay, Jr., Larry; Robitaille, George; Fling, Rick; McClung, Christina

    2005-01-01

    ...) utilizing the APG Standardized UXO Technology Demonstration Site Open Field. Scoring Records have been coordinated by Larry Overbay and the Standardized UXO Technology Demonstration Site Scoring Committee...

  3. Open Field Scoring Record No. 299

    National Research Council Canada - National Science Library

    Overbay, Larry; Robitaille, George

    2005-01-01

    ...) utilizing the YPG Standardized UXO Technology Demonstration Site Open Field. Scoring Records have been coordinated by Larry Overbay and the standardized UXO Technology Demonstration Site Scoring Committee...

  4. Slow decay of magnetic fields in open Friedmann universes

    International Nuclear Information System (INIS)

    Barrow, John D.; Tsagas, Christos G.

    2008-01-01

    Magnetic fields in Friedmann universes can experience superadiabatic growth without departing from conventional electromagnetism. The reason is the relativistic coupling between vector fields and spacetime geometry, which slows down the decay of large-scale magnetic fields in open universes, compared to that seen in perfectly flat models. The result is a large relative gain in magnetic strength that can lead to astrophysically interesting B fields, even if our Universe is only marginally open today

  5. Pre-geometrical field theory of the open string

    International Nuclear Information System (INIS)

    Nojiri, M.M.; Nojiri, Shin'ichi

    1988-01-01

    We propose a gauge invariant, background independent string action, which contains open and closed string fields and no kinetic terms. The kinetic term is generated through the condensation of the string fields, which is the solution of the equations of motion. We solve the equations and show that the action is classically equivalent to the open string action proposed by Hata et al. (orig.)

  6. Landscape history and archaeology of open field landscapes in Europe

    NARCIS (Netherlands)

    Renes, J.|info:eu-repo/dai/nl/071365303

    2016-01-01

    The landscapes of open fields were the grain baskets of medieval Europe. The term ‘open fields’ refers to the large arable fields that have an open character because the individual parcels of the owners were not surrounded by hedges, woodbanks, drystone walls or other visible boundaries. In this

  7. Can a marginally open universe amplify magnetic fields?

    International Nuclear Information System (INIS)

    Shtanov, Yuri; Sahni, Varun

    2013-01-01

    In a series of recent papers, including arXiv:1210.1183, it was claimed that large-scale magnetic fields generated during inflation in a spatially open universe could remain astrophysically significant at the present time since they experienced superadiabatic amplification specific to an open universe. We reexamine this assertion and show that, on the contrary, large-scale magnetic fields in a realistic open universe decay in much the same manner as they would in a spatially flat universe. Consequently, their amplitude today is extremely small (B 0 ∼ −59 G) and is unlikely to be of astrophysical significance

  8. Open bosonic string in background electromagnetic field

    International Nuclear Information System (INIS)

    Nesterenko, V.V.

    1987-01-01

    The classical and quantum dynamics of an open string propagating in the D-dimensional space-time in the presence of a background electromagnetic field is investigated. An important point in this consideration is the use of the generalized light-like gauge. There are considered the strings of two types; the neutral strings with charges at their ends obeying the condition q 1 +q 2 =0 and the charged strings having a net charge q 1 +q 2 ≠ 0. The consistency of theory demands that the background electric field does not exceed its critical value. The distance between the mass levels of the neutral open string decreases (1-e 2 ) times in comparison with the free string, where e is the dimensionless strength of the electric field. The magnetic field does not affect this distance. It is shown that at a classical level the squared mass of the neutral open string has a tachyonic contribution due to the motion of the string as a whole in transverse directions. The tachyonic term disappears if one considers, instead of M 2 , the string energy in a special reference frame where the projection of the total canonical momentum of the string onto the electric field vanishes. The contributions due to zero point fluctuations to the energy spectrum of the neutral string and to the Virasoro operators in the theory of charged string are found

  9. Proactive interference of open field on consummatory successive negative contrast.

    Science.gov (United States)

    Justel, Nadia; Pautassi, Ricardo; Mustaca, Alba

    2014-03-01

    Reactivity to a reward is affected by prior experience with the different reinforcer values of that reward, a phenomenon known as incentive relativity, which can be studied using the consummatory succesive negative contrast (cSNC) paradigm, in which the performance of animals that receive a 4 % sucrose solution after trials on which they were exposed to 32 % sucrose is compared with that of subjects that always receive the 4 % sucrose solution. The exploration of a novel open field can enhance or block the acquisition of associative and nonassociative memories. The effect of open field on cSNC has not yet been explored. The main result of the present study was that open-field exposure significantly modified the expression of cSNC. Exposure to an open field 1 h but not immediately before the downshift interfered with the expression of cSNC. These animals drank more of the downshifted reward than did controls that were not exposed to the apparatus, and this behavior persisted for up to three recovery trials. This phenomenon was observed even when the animals were given a more protracted preshift phase and when the discrepancy between the preshift and shift incentive values of sucrose were increased. An open field also interfered with incentive downshift when open-field exposure occurred 6 h before the downshift, and repeated exposure to the apparatus did not deteriorate this effect. The present study adds to a growing body of literature that indicates that open-field exploration can interfere with memory formation.

  10. The open innovation research landscape

    DEFF Research Database (Denmark)

    Bogers, Marcel; Zobel, Ann-Kristin; Afuah, Allan

    2017-01-01

    This paper provides an overview of the main perspectives and themes emerging in research on open innovation (OI). The paper is the result of a collaborative process among several OI scholars – having a common basis in the recurrent Professional Development Workshop on ‘Researching Open Innovation...... as questions for future research – particularly those that span across research domains that have so far developed in isolation.......’ at the Annual Meeting of the Academy of Management. In this paper, we present opportunities for future research on OI, organised at different levels of analysis. We discuss some of the contingencies at these different levels, and argue that future research needs to study OI – originally an organisational...

  11. Open superstring field theory on the restricted Hilbert space

    International Nuclear Information System (INIS)

    Konopka, Sebastian; Sachs, Ivo

    2016-01-01

    It appears that the formulation of an action for the Ramond sector of open superstring field theory requires to either restrict the Hilbert space for the Ramond sector or to introduce auxiliary fields with picture −3/2. The purpose of this note is to clarify the relation of the restricted Hilbert space with other approaches and to formulate open superstring field theory entirely in the small Hilbert space.

  12. The OpenAIRE Guide for Research Institutions

    Directory of Open Access Journals (Sweden)

    Gültekin Gürdal

    2013-11-01

    Full Text Available This text is transcript of OpenAIRE Guide which is prepared in order to help research institutions was released on 13.04.2011and translated with the cooperation of ANKOS Open Access and Institutional Repositories Grup members and OpenAIREplus project team of Turkey which is coordinated from Izmir Institute of Technology Library. OpenAIRE Project aims to support researchers in complying with the European Commission Seventh Framework Programme Open Access Pilot through a European Helpdesk System; support researchers in depositing their research publications in an institutional or disciplinary repository; build up an OpenAIRE portal and e-infrastructure for repository networks. The project will work in tadem with OpeanAIREplus Project which has the principal goal of creating a robust, participatory service for the cross-linking of peer-reviewed scientific publications and associated datasets.

  13. ITK: Enabling Reproducible Research and Open Science

    Directory of Open Access Journals (Sweden)

    Matthew Michael McCormick

    2014-02-01

    Full Text Available Reproducibility verification is essential to the practice of the scientific method. Researchers report their findings, which are strengthened as other independent groups in the scientific community share similar outcomes. In the many scientific fields where software has become a fundamental tool for capturing and analyzing data, this requirement of reproducibility implies that reliable and comprehensive software platforms and tools should be made available to the scientific community. The tools will empower them and the public to verify, through practice, the reproducibility of observations that are reported in the scientific literature.Medical image analysis is one of the fields in which the use of computational resources, both software and hardware, are an essential platform for performing experimental work. In this arena, the introduction of the Insight Toolkit (ITK in 1999 has transformed the field and facilitates its progress by accelerating the rate at which algorithmic implementations are developed, tested, disseminated and improved. By building on the efficiency and quality of open source methodologies, ITK has provided the medical image community with an effective platform on which to build a daily workflow that incorporates the true scientific practices of reproducibility verification.This article describes the multiple tools, methodologies, and practices that the ITK community has adopted, refined, and followed during the past decade, in order to become one of the research communities with the most modern reproducibility verification infrastructure. For example, 207 contributors have created over 2400 unit tests that provide over 84% code line test coverage. The Insight Journal, an open publication journal associated with the toolkit, has seen over 360,000 publication downloads. The median normalized closeness centrality, a measure of knowledge flow, resulting from the distributed peer code review system was high, 0.46.

  14. The free energies of partially open coronal magnetic fields

    Science.gov (United States)

    Low, B. C.; Smith, D. F.

    1993-01-01

    A simple model of the low corona is examined in terms of a static polytropic atmosphere in equilibrium with a global magnetic field. The question posed is whether magnetostatic states with partially open magnetic fields may contain magnetic energies in excess of those in fully open magnetic fields. Based on the analysis presented here, it is concluded that the cross-field electric currents in the pre-eruption corona are a viable source of the bulk of the energies in a mass ejection and its associated flare.

  15. Genetic and phenotypic correlations between feather pecking and open-field reponse in laying hens at two different ages

    NARCIS (Netherlands)

    Rodenburg, T.B.; Buitenhuis, A.J.; Ask, B.; Uitdehaag, K.A.; Koene, P.; Poel, van der J.J.; Arendonk, van J.A.M.; Bovenhuis, H.

    2004-01-01

    The object of this research was to study the relationship between feather pecking and open-field activity in laying hens at two different ages. A population of 550 birds of a laying hen cross was subjected to an open-field test at 5 and 29 weeks of age and to a social feather pecking test at 6 and

  16. Measuring Research Impact in an Open Access Environment

    Directory of Open Access Journals (Sweden)

    Frank Scholze

    2007-11-01

    Full Text Available This paper focuses on electronic publication impact as a limited, but rather well defined sub-field of research impact. With Open Access, a much bigger corpus of data has become available for statistical analysis. Publication impact can be measured by author- or reader-generated data. Author-generated data would be citations. Reader-generated data would be usage. Usage data can be collected through webserver or linkresolver logs. It has to be normalized in order to be shared and analysed meaningfully. The paper presents current initiatives and projects aiming to provide a suitable infrastructure, including publisher data (COUNTER/SUSHI and data collected from Open Access repositories (using OAI-PMH and OpenURL ContextObjects. Citation and usage data can be analyzed quantitatively or structurally. These new metrics can enhance or complement existing metrics like the Journal Impact Factor (JIF. Services like decision support systems for collection management or recommender systems can also be built on this metrics.

  17. The Systems Biology Research Tool: evolvable open-source software

    Directory of Open Access Journals (Sweden)

    Wright Jeremiah

    2008-06-01

    Full Text Available Abstract Background Research in the field of systems biology requires software for a variety of purposes. Software must be used to store, retrieve, analyze, and sometimes even to collect the data obtained from system-level (often high-throughput experiments. Software must also be used to implement mathematical models and algorithms required for simulation and theoretical predictions on the system-level. Results We introduce a free, easy-to-use, open-source, integrated software platform called the Systems Biology Research Tool (SBRT to facilitate the computational aspects of systems biology. The SBRT currently performs 35 methods for analyzing stoichiometric networks and 16 methods from fields such as graph theory, geometry, algebra, and combinatorics. New computational techniques can be added to the SBRT via process plug-ins, providing a high degree of evolvability and a unifying framework for software development in systems biology. Conclusion The Systems Biology Research Tool represents a technological advance for systems biology. This software can be used to make sophisticated computational techniques accessible to everyone (including those with no programming ability, to facilitate cooperation among researchers, and to expedite progress in the field of systems biology.

  18. Inexpensive Open-Source Data Logging in the Field

    Science.gov (United States)

    Wickert, A. D.

    2013-12-01

    I present a general-purpose open-source field-capable data logger, which provides a mechanism to develop dense networks of inexpensive environmental sensors. This data logger was developed as a low-power variant of the Arduino open-source development system, and is named the ALog ("Arduino Logger") BottleLogger (it is slim enough to fit inside a Nalgene water bottle) version 1.0. It features an integrated high-precision real-time clock, SD card slot for high-volume data storage, and integrated power switching. The ALog can interface with sensors via six analog/digital pins, two digital pins, and one digital interrupt pin that can read event-based inputs, such as those from a tipping-bucket rain gauge. We have successfully tested the ALog BottleLogger with ultrasonic rangefinders (for water stage and snow accumulation and melt), temperature sensors, tipping-bucket rain gauges, soil moisture and water potential sensors, resistance-based tools to measure frost heave, and cameras that it triggers based on events. The source code for the ALog, including functions to interface with a a range of commercially-available sensors, is provided as an Arduino C++ library with example implementations. All schematics, circuit board layouts, and source code files are open-source and freely available under GNU GPL v3.0 and Creative Commons Attribution-ShareAlike 3.0 Unported licenses. Through this work, we hope to foster a community-driven movement to collect field environmental data on a budget that permits citizen-scientists and researchers from low-income countries to collect the same high-quality data as researchers in wealthy countries. These data can provide information about global change to managers, governments, scientists, and interested citizens worldwide. Watertight box with ALog BottleLogger data logger on the left and battery pack with 3 D cells on the right. Data can be collected for 3-5 years on one set of batteries.

  19. Open string in the constant B-field background

    International Nuclear Information System (INIS)

    Jing Jian; Long Zhengwen

    2005-01-01

    A new method is proposed to quantize open strings in this paper. To illustrate our method, we analyze free open string as well as open string in the D-brane background with a nonvanishing B-field, respectively. The Poisson brackets among Fourier components are obtained firstly then we get the Poisson brackets among open string's coordinates. The noncommutativity of coordinates along the D-brane is reproduced. Some ambiguities in the previous discussions can be avoided

  20. Analytic solutions for marginal deformations in open superstring field theory

    International Nuclear Information System (INIS)

    Okawa, Y.

    2007-04-01

    We extend the calculable analytic approach to marginal deformations recently developed in open bosonic string field theory to open superstring field theory formulated by Berkovits. We construct analytic solutions to all orders in the deformation parameter when operator products made of the marginal operator and the associated superconformal primary field are regular. (orig.)

  1. Classical open-string field theory: A∞-algebra, renormalization group and boundary states

    International Nuclear Information System (INIS)

    Nakatsu, Toshio

    2002-01-01

    We investigate classical bosonic open-string field theory from the perspective of the Wilson renormalization group of world-sheet theory. The microscopic action is identified with Witten's covariant cubic action and the short-distance cut-off scale is introduced by length of open-string strip which appears in the Schwinger representation of open-string propagator. Classical open-string field theory in the title means open-string field theory governed by a classical part of the low energy action. It is obtained by integrating out suitable tree interactions of open-strings and is of non-polynomial type. We study this theory by using the BV formalism. It turns out to be deeply related with deformation theory of A ∞ -algebra. We introduce renormalization group equation of this theory and discuss it from several aspects. It is also discussed that this theory is interpreted as a boundary open-string field theory. Closed-string BRST charge and boundary states of closed-string field theory in the presence of open-string field play important roles

  2. Piranti Lunak Pengujian Struktur Matematika Grup, Ring, Field Berbasis Osp (Open Source Program

    Directory of Open Access Journals (Sweden)

    Ngarap Im Manik

    2014-06-01

    Full Text Available This design of a computer software is a development and continuation of the software made on the previous research (2009/2010. However, this further research developed and expanded the scopes of testing more on the Siclic Group, Isomorphism Group, Semi Group, Sub Group and Abelian Group, Factor Ring, Sub Ring and Polynomial Ring; developed on the OSP (Open Source Program-based. The software was developed using the OSP-based language programming, such Java, so it is open and free to use for its users. This research succeeded to develop an open source software of Java program that can be used for testing specific mathematical Groups, such Ciclic Group, Isomorphism Group, Semi Group, Sub Group and Abelian Group, and Rings, Commutative Ring, Division Ring, Ideal Sub Ring, Ring Homomorphism, Ring Epimorphism and Fields. By the results, the software developed was able to test as same as the results from manual testing.

  3. Energy momentum tensor and marginal deformations in open string field theory

    International Nuclear Information System (INIS)

    Sen, Ashoke

    2004-01-01

    Marginal boundary deformations in a two dimensional conformal field theory correspond to a family of classical solutions of the equations of motion of open string field theory. In this paper we develop a systematic method for relating the parameter labelling the marginal boundary deformation in the conformal field theory to the parameter labelling the classical solution in open string field theory. This is done by first constructing the energy-momentum tensor associated with the classical solution in open string field theory using Noether method, and then comparing this to the answer obtained in the conformal field theory by analysing the boundary state. We also use this method to demonstrate that in open string field theory the tachyon lump solution on a circle of radius larger than one has vanishing pressure along the circle direction, as is expected for a co-dimension one D-brane. (author)

  4. Stepping up Open Science Training for European Research

    Directory of Open Access Journals (Sweden)

    Birgit Schmidt

    2016-06-01

    Full Text Available Open science refers to all things open in research and scholarly communication: from publications and research data to code, models and methods as well as quality evaluation based on open peer review. However, getting started with implementing open science might not be as straightforward for all stakeholders. For example, what do research funders expect in terms of open access to publications and/or research data? Where and how to publish research data? How to ensure that research results are reproducible? These are all legitimate questions and, in particular, early career researchers may benefit from additional guidance and training. In this paper we review the activities of the European-funded FOSTER project which organized and supported a wide range of targeted trainings for open science, based on face-to-face events and on a growing suite of e-learning courses. This article reviews the approach and experiences gained from the first two years of the project.

  5. Open field modifications needed to measure, in the mouse, exploration- driven ambulation and fear of open space.

    OpenAIRE

    Vidal Gómez, José

    2014-01-01

    The open field test is used to assess ambulation and anxiety; one way to assess anxiety is to compare ambulation in the center with ambulation in the periphery: the more anxious is the mouse, the less it moves in the center. The results of this report cast doubts on the generality of that rule, because they show that ambulation, both in the center and in the periphery, depends on the mouse strain and on the size of the open field; specifically, in a brightly lit open-field of moderate size (3...

  6. Towards an Open Software Platform for Field Robots in Precision Agriculture

    Directory of Open Access Journals (Sweden)

    Kjeld Jensen

    2014-06-01

    Full Text Available Robotics in precision agriculture has the potential to improve competitiveness and increase sustainability compared to current crop production methods and has become an increasingly active area of research. Tractor guidance systems for supervised navigation and implement control have reached the market, and prototypes of field robots performing precision agriculture tasks without human intervention also exist. But research in advanced cognitive perception and behaviour that is required to enable a more efficient, reliable and safe autonomy becomes increasingly demanding due to the growing software complexity. A lack of collaboration between research groups contributes to the problem. Scientific publications describe methods and results from the work, but little field robot software is released and documented for others to use. We hypothesize that a common open software platform tailored to field robots in precision agriculture will significantly decrease development time and resources required to perform experiments due to efficient reuse of existing work across projects and robot platforms. In this work we present the FroboMind software platform and evaluate the performance when applied to precision agriculture tasks.

  7. The Systems Biology Research Tool: evolvable open-source software

    OpenAIRE

    Wright, J; Wagner, A

    2008-01-01

    Abstract Background Research in the field of systems biology requires software for a variety of purposes. Software must be used to store, retrieve, analyze, and sometimes even to collect the data obtained from system-level (often high-throughput) experiments. Software must also be used to implement mathematical models and algorithms required for simulation and theoretical predictions on the system-level. Results We introduce a free, easy-to-use, open-source, integrated software platform calle...

  8. Thermodynamic properties of open noncritical string in external electromagnetic field

    International Nuclear Information System (INIS)

    Lichtzier, I.M.; Odintsov, S.D.; Bytsenko, A.A.

    1991-01-01

    We investigate the thermodynamics of open noncritical string (charged and neutral) in an external constant magnetic field. The free energy and Hagedorn temperature are calculated. It is shown that Hagedorn temperature is the same as in the absence of constant magnetic field. We present also the expressions for the free energy and Hagedorn temperature of the neutral open noncritical string in an external constant electromagnetic field. In this case Hagedorn temperature depends on the external electric field. (author)

  9. Opening the "black box" of current creativity research

    DEFF Research Database (Denmark)

    Hoffmann Birk, Rasmus; Ernø, Steffen

    -2012. The sub-fields were chosen because of their prominence in psychological research and research on creativity. The articles were procured from the PsycINFO database, with selection criteria being that they must be peer-reviewed and empirical studies. Typical definitions of creativity were "novelty plus...... value" or none at all. Creativity was mostly measured with different types of divergent thinking tests. There appears to be a lack of deeper theoretical and methodological discussions of creativity in the literature, which creates a disconnection between definitions, methodologies and the interpretation...... of empirical findings in regards to creativity as a phenomenon. Creativity itself thus becomes a "black box", rarely opened to investigation. Creativity research could therefore benefit from a more sustained relfection over its theoretical and methodological underpinnings as well as shifting its focus towards...

  10. Deformation of the cubic open string field theory

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Taejin, E-mail: taejin@kangwon.ac.kr

    2017-05-10

    We study a consistent deformation of the cubic open bosonic string theory in such a way that the non-planar world sheet diagrams of the perturbative string theory are mapped onto their equivalent planar diagrams of the light-cone string field theory with some length parameters fixed. An explicit evaluation of the cubic string vertex in the zero-slope limit yields the correct relationship between the string coupling constant and the Yang–Mills coupling constant. The deformed cubic open string field theory is shown to produce the non-Abelian Yang–Mills action in the zero-slope limit if it is defined on multiple D-branes. Applying the consistent deformation systematically to multi-string world sheet diagrams, we may be able to calculate scattering amplitudes with an arbitrary number of external open strings.

  11. Deformation of the cubic open string field theory

    International Nuclear Information System (INIS)

    Lee, Taejin

    2017-01-01

    We study a consistent deformation of the cubic open bosonic string theory in such a way that the non-planar world sheet diagrams of the perturbative string theory are mapped onto their equivalent planar diagrams of the light-cone string field theory with some length parameters fixed. An explicit evaluation of the cubic string vertex in the zero-slope limit yields the correct relationship between the string coupling constant and the Yang–Mills coupling constant. The deformed cubic open string field theory is shown to produce the non-Abelian Yang–Mills action in the zero-slope limit if it is defined on multiple D-branes. Applying the consistent deformation systematically to multi-string world sheet diagrams, we may be able to calculate scattering amplitudes with an arbitrary number of external open strings.

  12. Deformation of the cubic open string field theory

    Directory of Open Access Journals (Sweden)

    Taejin Lee

    2017-05-01

    Full Text Available We study a consistent deformation of the cubic open bosonic string theory in such a way that the non-planar world sheet diagrams of the perturbative string theory are mapped onto their equivalent planar diagrams of the light-cone string field theory with some length parameters fixed. An explicit evaluation of the cubic string vertex in the zero-slope limit yields the correct relationship between the string coupling constant and the Yang–Mills coupling constant. The deformed cubic open string field theory is shown to produce the non-Abelian Yang–Mills action in the zero-slope limit if it is defined on multiple D-branes. Applying the consistent deformation systematically to multi-string world sheet diagrams, we may be able to calculate scattering amplitudes with an arbitrary number of external open strings.

  13. Open Access Centre at the Nature Research Centre: a facility for enhancement of scientific research, education and public outreach in Lithuania

    Science.gov (United States)

    Šerpenskienė, Silvija; Skridlaitė, Gražina

    2014-05-01

    Open Access Centre (OAC) was established in Vilnius, Lithuania in 2013 as a subdivision of the Nature Research Centre (NRC) operating on the principle of open access for both internal and external users. The OAC consists of 15 units, i.e. 15 NRC laboratories or their branches. Forty four sets of research equipment were purchased. The OAC cooperates with Lithuanian science and studies institutions, business sector and other governmental and public institutions. Investigations can be carried in the Geosciences, Biotaxonomy, Ecology and Molecular Research, and Ecotoxicology fields. Environmental radioactivity, radioecology, nuclear geophysics, microscopic and chemical composition of natural compounds (minerals, rocks etc.), paleomagnetic, magnetic and environmental investigations, as well as ground and water contamination by oil products and other organic environment polluting compounds, identification of fossils, rocks and minerals can be studied in the Georesearch field. Ecosystems and identification of plants, animals and microorganisms are main subjects of the Biotaxonomy, Ecology and Molecular Research field. The Ecotoxicologal Research deals with toxic and genotoxic effects of toxic substances and other sources of pollution on macro- and microorganisms and cell cultures. Open access is guaranteed by: (1) providing scientific research and experimental development services; (2) implementing joint business and science projects; (3) using facilities for the training of specialists of the highest qualifications; (4) providing properly qualified and technically trained users with opportunities to carry out their scientific research and/or experiments in the OAC laboratories by themselves. Services provided in the Open Access Centre can be received by both internal and external users: persons undertaking innovative economic activities, students of other educational institutions, interns, external teams of researchers engaged in scientific research activities, teachers

  14. Management of whitefly-transmitted viruses in open-field production systems

    Science.gov (United States)

    Whiteflies are a key pest of crops in open field production throughout the tropics and subtropics. This is due in large part to the long and diverse list of devastating plant viruses transmitted by these vectors. Open field production provides many challenges to manage these viruses and in many case...

  15. Supporting open access to clinical trial data for researchers: The Duke Clinical Research Institute-Bristol-Myers Squibb Supporting Open Access to Researchers Initiative.

    Science.gov (United States)

    Pencina, Michael J; Louzao, Darcy M; McCourt, Brian J; Adams, Monique R; Tayyabkhan, Rehbar H; Ronco, Peter; Peterson, Eric D

    2016-02-01

    There are growing calls for sponsors to increase transparency by providing access to clinical trial data. In response, Bristol-Myers Squibb and the Duke Clinical Research Institute have collaborated on a new initiative, Supporting Open Access to Researchers. The aim is to facilitate open sharing of Bristol-Myers Squibb trial data with interested researchers. Key features of the Supporting Open Access to Researchers data sharing model include an independent review committee that ensures expert consideration of each proposal, stringent data deidentification/anonymization and protection of patient privacy, requirement of prespecified statistical analysis plans, and independent review of manuscripts before submission for publication. We believe that these approaches will promote open science by allowing investigators to verify trial results as well as to pursue interesting secondary uses of trial data without compromising scientific integrity. Copyright © 2015 Elsevier Inc. All rights reserved.

  16. Supersymmetry in open superstring field theory

    Energy Technology Data Exchange (ETDEWEB)

    Erler, Theodore [Arnold Sommerfeld Center, Ludwig-Maximilians University,Theresienstrasse 37, 80333 Munich (Germany)

    2017-05-19

    We realize the 16 unbroken supersymmetries on a BPS D-brane as invariances of the action of the corresponding open superstring field theory. We work in the small Hilbert space approach, where a symmetry of the action translates into a symmetry of the associated cyclic A{sub ∞} structure. We compute the supersymmetry algebra, being careful to disentangle the components which produce a translation, a gauge transformation, and a symmetry transformation which vanishes on-shell. Via the minimal model theorem, we illustrate how supersymmetry of the action implies supersymmetry of the tree level open string scattering amplitudes.

  17. Regularizing cubic open Neveu-Schwarz string field theory

    International Nuclear Information System (INIS)

    Berkovits, Nathan; Siegel, Warren

    2009-01-01

    After introducing non-minimal variables, the midpoint insertion of Y Y-bar in cubic open Neveu-Schwarz string field theory can be replaced with an operator N ρ depending on a constant parameter ρ. As in cubic open superstring field theory using the pure spinor formalism, the operator N ρ is invertible and is equal to 1 up to a BRST-trivial quantity. So unlike the linearized equation of motion Y Y-bar QV = 0 which requires truncation of the Hilbert space in order to imply QV = 0, the linearized equation N ρ QV = 0 directly implies QV = 0.

  18. Identification of High-Variation Fields based on Open Satellite Imagery

    DEFF Research Database (Denmark)

    Jeppesen, Jacob Høxbroe; Jacobsen, Rune Hylsberg; Nyholm Jørgensen, Rasmus

    2017-01-01

    . The categorization is based on vegetation indices derived from Sentinel-2 satellite imagery. A case study on 7678 winter wheat fields is presented, which employs open data and open source software to analyze the satellite imagery. Furthermore, the method can be automated to deliver categorizations at every update......This paper proposes a simple method for categorizing fields on a regional level, with respect to intra-field variations. It aims to identify fields where the potential benefits of applying precision agricultural practices are highest from an economic and environmental perspective...

  19. Collaboratively Analysing Open Research Data in Virtual Research Environments–New Visionary Use Cases

    NARCIS (Netherlands)

    Zuiderwijk-van Eijk, AMG; Matheus, R.

    Virtual Research Environments (VREs) offer new opportunities for collaboratively analysing open research data. This workshop builds on a workshop that we gave at CeDEM16 and aims to refine and discuss requirements for collaboratively analysing Open Government Data (OGD) and open research data

  20. Open Science: Open source licenses in scientific research

    OpenAIRE

    Guadamuz, Andres

    2006-01-01

    The article examines the validity of OSS (open source software) licenses for scientific, as opposed to creative works. It draws on examples of OSS licenses to consider their suitability for the scientific community and scientific research.

  1. Open Innovation in Research Libraries-Myth or Reality?

    DEFF Research Database (Denmark)

    Scupola, Ada; W. Nicolajsen, Hanne

    2009-01-01

      In this article we investigate open innovation in a non commercial setting: research libraries. The research questions are: Do academic libraries engage in open innovation processes? If so, what are the most important actors in e-services innovation and development and what is their role......? By drawing on earlier research on open innovation, new product development and new service development a case study at Roskilde University Library is conducted. We found that research libraries are indeed engaging in open innovation, especially involving competitors, government agencies and users....... In particular collaboration with other Danish research libraries and governmental agencies are important in setting the visions and strategies for e-services innovations; users have a more limited role....

  2. Open Innovation in Research Libraries-Myth or Reality?

    DEFF Research Database (Denmark)

    Scupola, Ada; Nicolajsen, Hanne Westh

    2010-01-01

    In this article we investigate open innovation in a non commercial setting: research libraries. The research questions are: Do academic libraries engage in open innovation processes? If so, what are the most important actors in e-services innovation and development and what is their role......? By drawing on earlier research on open innovation, new product development and new service development a case study at Roskilde University Library is conducted. We found that research libraries are indeed engaging in open innovation, especially involving competitors, government agencies and users....... In particular collaboration with other Danish research libraries and governmental agencies are important in setting the visions and strategies for e-services innovations; users have a more limited role....

  3. Open-field behavior of house mice selectively bred for high voluntary wheel-running.

    Science.gov (United States)

    Bronikowski, A M; Carter, P A; Swallow, J G; Girard, I A; Rhodes, J S; Garland, T

    2001-05-01

    Open-field behavioral assays are commonly used to test both locomotor activity and emotionality in rodents. We performed open-field tests on house mice (Mus domesticus) from four replicate lines genetically selected for high voluntary wheel-running for 22 generations and from four replicate random-bred control lines. Individual mice were recorded by video camera for 3 min in a 1-m2 open-field arena on 2 consecutive days. Mice from selected lines showed no statistical differences from control mice with respect to distance traveled, defecation, time spent in the interior, or average distance from the center of the arena during the trial. Thus, we found little evidence that open-field behavior, as traditionally defined, is genetically correlated with wheel-running behavior. This result is a useful converse test of classical studies that report no increased wheel-running in mice selected for increased open-field activity. However, mice from selected lines turned less in their travel paths than did control-line mice, and females from selected lines had slower travel times (longer latencies) to reach the wall. We discuss these results in the context of the historical open-field test and newly defined measures of open-field activity.

  4. Open Research Data: From Vision to Practice

    CERN Document Server

    Pampel, Heinz

    2014-01-01

    “To make progress in science, we need to be open and share.” This quote from Neelie Kroes (2012), vice president of the European Commission describes the growing public demand for an Open Science. Part of Open Science is, next to Open Access to peer-reviewed publications, the Open Access to research data, the basis of scholarly knowledge. The opportunities and challenges of Data Sharing are discussed widely in the scholarly sector. The cultures of Data Sharing differ within the scholarly disciplines. Well advanced are for example disciplines like biomedicine and earth sciences. Today, more and more funding agencies require a proper Research Data Management and the possibility of data re-use. Many researchers often see the potential of Data Sharing, but they act cautiously. This situation shows a clear ambivalence between the demand for Data Sharing and the current practice of Data Sharing. Starting from a baseline study on current discussions, practices and developments the article describe the challenges...

  5. OpenSubspace

    DEFF Research Database (Denmark)

    Müller, Emmanuel; Assent, Ira; Günnemann, Stephan

    2009-01-01

    Subspace clustering and projected clustering are recent research areas for clustering in high dimensional spaces. As the field is rather young, there is a lack of comparative studies on the advantages and disadvantages of the different algorithms. Part of the underlying problem is the lack...... of available open source implementations that could be used by researchers to understand, compare, and extend subspace and projected clustering algorithms. In this paper, we discuss the requirements for open source evaluation software. We propose OpenSubspace, an open source framework that meets...... these requirements. OpenSubspace integrates state-of-the-art performance measures and visualization techniques to foster research in subspace and projected clustering....

  6. In an Age of Open Access to Research Policies: Physician and Public Health NGO Staff Research Use and Policy Awareness.

    Science.gov (United States)

    Moorhead, Laura L; Holzmeyer, Cheryl; Maggio, Lauren A; Steinberg, Ryan M; Willinsky, John

    2015-01-01

    Through funding agency and publisher policies, an increasing proportion of the health sciences literature is being made open access. Such an increase in access raises questions about the awareness and potential utilization of this literature by those working in health fields. A sample of physicians (N=336) and public health non-governmental organization (NGO) staff (N=92) were provided with relatively complete access to the research literature indexed in PubMed, as well as access to the point-of-care service UpToDate, for up to one year, with their usage monitored through the tracking of web-log data. The physicians also participated in a one-month trial of relatively complete or limited access. The study found that participants' research interests were not satisfied by article abstracts alone nor, in the case of the physicians, by a clinical summary service such as UpToDate. On average, a third of the physicians viewed research a little more frequently than once a week, while two-thirds of the public health NGO staff viewed more than three articles a week. Those articles were published since the 2008 adoption of the NIH Public Access Policy, as well as prior to 2008 and during the maximum 12-month embargo period. A portion of the articles in each period was already open access, but complete access encouraged a viewing of more research articles. Those working in health fields will utilize more research in the course of their work as a result of (a) increasing open access to research, (b) improving awareness of and preparation for this access, and (c) adjusting public and open access policies to maximize the extent of potential access, through reduction in embargo periods and access to pre-policy literature.

  7. Main trends in scientific-research works during construction and operation of uranium mines and open cuts

    International Nuclear Information System (INIS)

    Mosinets, V.N.

    1993-01-01

    Consideration is given to main trends in research works during construction and operation of uranium mines and open cuts of Priargunsky mine-chemical association. Develops and introduced principally new design solutions and technologies in the field of open mining, underground mining, as well as in-situ and heap leaching, are described

  8. Anxiolytic effects of lavender oil inhalation on open-field behaviour in rats.

    Science.gov (United States)

    Shaw, D; Annett, J M; Doherty, B; Leslie, J C

    2007-09-01

    To establish a valid animal model of the effects of olfactory stimuli on anxiety, a series of experiments was conducted using rats in an open-field test. Throughout, effects of lavender oil were compared with the effects of chlordiazepoxide (CDP), as a reference anxiolytic with well-known effects on open-field behaviour. Rats were exposed to lavender oil (0.1-1.0 ml) for 30 min (Experiment 1) or 1h (Experiment 2) prior to open-field test and in the open field or injected with CDP (10 mg/kg i.p.). CDP had predicted effects on behaviour, and the higher doses of lavender oil had some effects on behaviour similar to those of CDP. In Experiment 3, various combinations of pre-exposure times and amounts of lavender oil were used. With sufficient exposure time and quantity of lavender the same effects were obtained as in Experiment 2. Experiment 4 demonstrated that these behavioural effects of lavender could be obtained following pre-exposure, even if no oil was present in the open-field test. In Experiments 2-4, lavender oil increased immobility. Together, these experiments suggest that lavender oil does have anxiolytic effects in the open field, but that a sedative effect can also occur at the highest doses.

  9. Development of an open metadata schema for prospective clinical research (openPCR) in China.

    Science.gov (United States)

    Xu, W; Guan, Z; Sun, J; Wang, Z; Geng, Y

    2014-01-01

    In China, deployment of electronic data capture (EDC) and clinical data management system (CDMS) for clinical research (CR) is in its very early stage, and about 90% of clinical studies collected and submitted clinical data manually. This work aims to build an open metadata schema for Prospective Clinical Research (openPCR) in China based on openEHR archetypes, in order to help Chinese researchers easily create specific data entry templates for registration, study design and clinical data collection. Singapore Framework for Dublin Core Application Profiles (DCAP) is used to develop openPCR and four steps such as defining the core functional requirements and deducing the core metadata items, developing archetype models, defining metadata terms and creating archetype records, and finally developing implementation syntax are followed. The core functional requirements are divided into three categories: requirements for research registration, requirements for trial design, and requirements for case report form (CRF). 74 metadata items are identified and their Chinese authority names are created. The minimum metadata set of openPCR includes 3 documents, 6 sections, 26 top level data groups, 32 lower data groups and 74 data elements. The top level container in openPCR is composed of public document, internal document and clinical document archetypes. A hierarchical structure of openPCR is established according to Data Structure of Electronic Health Record Architecture and Data Standard of China (Chinese EHR Standard). Metadata attributes are grouped into six parts: identification, definition, representation, relation, usage guides, and administration. OpenPCR is an open metadata schema based on research registration standards, standards of the Clinical Data Interchange Standards Consortium (CDISC) and Chinese healthcare related standards, and is to be publicly available throughout China. It considers future integration of EHR and CR by adopting data structure and data

  10. Dimensions of Open Research: Critical Reflections on Openness in the ROER4D Project

    Science.gov (United States)

    King, Thomas; Hodgkinson-Williams, Cheryl; Willmers, Michelle; Walji, Sukaina

    2016-01-01

    Open Research has the potential to advance the scientific process by improving the transparency, rigour, scope and reach of research, but choosing to experiment with Open Research carries with it a set of ideological, legal, technical and operational considerations. Researchers, especially those in resource-constrained situations, may not be aware…

  11. Particle-in-cell simulations of plasma opening switch with external magnetic field

    International Nuclear Information System (INIS)

    Chen Yulan; Zeng Zhengzhong; Sun Fengju

    2003-01-01

    Fully electromagnetic particle-in-cell simulations are performed to study the effects of an external magnetic field on coaxial plasma opening switch (POS). The simulation results show that POS opening performance can be significantly improved only when external longitudinal magnetic field coils are placed at the cathode side, and an additional azimuthal magnetic field is effective whether the central electrode is of positive or negative polarity. Voltage multiplication coefficient K rises with the additional magnetic field increasing till the electron current is completely magnetically insulated during the opening of POS

  12. Arab Researchers Promotions of Open Archives and Free

    Directory of Open Access Journals (Sweden)

    Abd Al-Majid Salih Bu Azza

    2006-09-01

    Full Text Available A study aiming at measuring the promotion of Arab researches for Open Archives and Free Electronic Journal, contained 60 researches in Sultan Qabus university in Oman, and discovered their opinion about open access resources. It found that 78.8 % of researchers did not publish articles in Free Electronic Journals, and 77.8 % do not aware about the international imitative of Open Access. Also discovered that researchers refuse publishing their articles in e-journals because of electronic articles are not considered in their universities.

  13. Boundary string field theory and an open string one-loop

    International Nuclear Information System (INIS)

    Lee, Tae Jin; Viswanathan, K. S.; Yang, Yi

    2003-01-01

    We discuss the open string one-loop partition function in the tachyon condensation background of an unstable D-brane system. We evaluate the partition function by using the boundary-state formulation and find that it is in complete agreement with the result obtained in the boundary string field theory. This suggests that the open string higher loop diagrams may be produced consistently by using a closed string field theory, where the D-brane plays the role of a source for the closed string field

  14. Field studies courses open

    Science.gov (United States)

    Fourteen month-long courses combining applied academics with training in field research methodology are being offered this summer by the School for Field Studies. The courses, held in eight countries during May, June, July, and August, provide unique opportunities for participants to work as a team under primitive conditions.‘Our courses bind together the academic challenge of the research problem, the physical challenge of the site itself, and the interpersonal challenge of the expedition team in a dynamic way so that both cognitive and affective learning are accelerated,’ according to Jim Elder, the school's director.

  15. On multiplying methods in the field of research evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Derrick, G.; Molas-Gallart, J.; De Rijcke, S.; Meijer, I.; Van der Weijden, I.; Wouters, P.

    2016-07-01

    This special session forms part of a larger program aimed at the multiplication and integration of methodological approaches in the research evaluation and innovation policy field. The session builds on previous initiatives by Gemma Derrick and colleagues at CWTS, INGENIO, the Rathenau Instituut and SPRU, exploring the advantages of qualitative methodological tools at the STI/ENID conference in Lugano, and an international workshop in London in October 2015. The program is highly topical: the research evaluation field is currently reconsidering its methodological foundations in light of new research questions arising from policy initiatives regarding a) the move toward open science; b) a reconceptualization of research excellence to include societal relevance; c) diversification of academic careers, and d) the search for indicators showcasing responsible research behavior and innovation. This new special session at STI2016 will advance and broaden the scope of previous initiatives by building bridges between cutting edge research involving quantitative, qualitative, and mixed methodological research designs. Bringing together leading experts and promising researchers with distinctive methodological skill-sets, the session will demonstrate the advantages of cross-fertilization between ‘core’ and ‘peripheral’ methodological approaches for the research evaluation and science indicators field. (Author)

  16. Parallel inhomogeneity and the Alfven resonance. 1: Open field lines

    Science.gov (United States)

    Hansen, P. J.; Harrold, B. G.

    1994-01-01

    In light of a recent demonstration of the general nonexistence of a singularity at the Alfven resonance in cold, ideal, linearized magnetohydrodynamics, we examine the effect of a small density gradient parallel to uniform, open ambient magnetic field lines. To lowest order, energy deposition is quantitatively unaffected but occurs continuously over a thickened layer. This effect is illustrated in a numerical analysis of a plasma sheet boundary layer model with perfectly absorbing boundary conditions. Consequences of the results are discussed, both for the open field line approximation and for the ensuing closed field line analysis.

  17. Interacting open Wilson lines from noncommutative field theories

    International Nuclear Information System (INIS)

    Kiem, Youngjai; Lee, Sangmin; Rey, Soo-Jong; Sato, Haru-Tada

    2002-01-01

    In noncommutative field theories, it is known that the one-loop effective action describes the propagation of noninteracting open Wilson lines, obeying the flying dipole's relation. We show that the two-loop effective action describes the cubic interaction among 'closed string' states created by open Wilson line operators. Taking d-dimensional λ[Φ 3 ] * theory as the simplest setup, we compute the nonplanar contribution at a low-energy and large noncommutativity limit. We find that the contribution is expressible in a remarkably simple cubic interaction involving scalar open Wilson lines only and nothing else. We show that the interaction is purely geometrical and noncommutative in nature, depending only on the size of each open Wilson line

  18. Open Bibliography

    OpenAIRE

    Murray-Rust, Peter; Pollock, Rufus; MacGillivray, Mark; O'Steen, Ben; Waites, William

    2011-01-01

    Poster presented at the VSMF Symposium held at the Unilever Centre on 2011-01-17. More research is published currently than can be understood or followed by a researcher without the aid of a computer. We need Open shareable information on research publications, an Open Bibliography, to build the services that enable researchers to explore their field and discover the research they need. Producers of bibliographic data such as libraries, publishers, universities, scholars or social referenc...

  19. Research Note The reliability of a field test kit for the detection and ...

    African Journals Online (AJOL)

    Research Note The reliability of a field test kit for the detection and the persistence of ... Open Access DOWNLOAD FULL TEXT ... The objectives were to test a field kit for practicality and reliability, to assess the spread of the bacteria among ...

  20. Evidence for open field lines in Jupiter's magnetosphere

    Science.gov (United States)

    Goertz, C. K.; Randall, B. A.; Thomsen, M. F.; Jones, D. E.; Smith, E. J.

    1976-01-01

    A model for the night-side Jovian magnetic field is derived partly on the basis of theoretical considerations and partly on the basis of the magnetic-field data obtained during the outbound leg of the path of Pioneer 10. This model can explain the observed sawtooth modulation of energetic particle fluxes in terms of closed and open field lines that cannot contain the particles. The model is applicable only to the Jovian magnetotail.

  1. Documentation in Otolaryngology. Sharing Otolaryngology research data in an open science ecosyste

    Directory of Open Access Journals (Sweden)

    Fernanda PESET

    2018-01-01

    Full Text Available Introduction and objective: The present text addresses the most significant aspects to share research data in otolaryngology in the context of open science as an ecosystem. Its aim is to offer a panoramic view that helps the researcher to manage their data as part of enriched science. Method: A bibliographical review and of the own experience in the field of the investigation data was performed. Results: The basic pillars for success are offered: its political, technical and necessary capacities. Discussion: The tasks of making data available should be recognized as part of the researcher's curriculum because documenting them to be reusable is a highly specialized and time-consuming task. Conclusions: It is considered that we are at a crucial moment to begin to share data. It is being considered in all scientific policy scenarios as in the EU through the European Open Science Computing.

  2. Olfactory source localization in the open field using one or both nostrils.

    Science.gov (United States)

    Welge-Lussen, A; Looser, G L; Westermann, B; Hummel, T

    2014-03-01

    This study aims to examine humans ́ abilities to localize odorants within the open field. Young participants were tested on a localization task using a relatively selective olfactory stimulus (2-phenylethyl-alcohol, PEA) and cineol, an odorant with a strong trigeminal component. Participants were blindfolded and had to localize an odorant source at 2 m distance (far-field condition) and a 0.4 m distance (near-field condition) with either two nostrils open or only one open nostril. For the odorant with trigeminal properties, the number of correct trials did not differ when one or both nostrils were used, while more PEA localization trials were correctly completed with both rather than one nostril. In the near-field condition, correct localization was possible in 72-80% of the trials, irrespective of the odorant and the number of nostrils used. Localization accuracy, measured as spatial deviation from the olfactory source, was significantly higher in the near-field compared to the far-field condition, but independent of the odorant being localized. Odorant localization within the open field is difficult, but possible. In contrast to the general view, humans seem to be able to exploit the two-nostril advantage with increasing task difficulty.

  3. Evidence for extreme divergence of open field lines from solar activity

    International Nuclear Information System (INIS)

    Dulk, G.A.; Suzuki, S.; Melrose, D.B.

    1979-01-01

    This paper reviews the evidence on the structure of the open magnetic field lines that emerge from solar active regions into interplanetary space. The evidence comes mainly from the measured sizes, positions and polarization of Type III and Type V bursts, and from electron streams observed from space. It is found that the observations are best interpreted in terms of a strongly-diverging field topology, with the open field lines filling a cone of angle approx. 60 0

  4. Open membranes in a constant C-field background and noncommutative boundary strings

    International Nuclear Information System (INIS)

    Kawamoto, Shoichi; Sasakura, Naoki

    2000-01-01

    We investigate the dynamics of open membrane boundaries in a constant C-field background. We follow the analysis for open strings in a B-field background, and take some approximations. We find that open membrane boundaries do show noncommutativity in this case by explicit calculations. Membrane boundaries are one dimensional strings, so we face a new type of noncommutativity, that is, noncommutative strings. (author)

  5. Open Access Research via Collaborative Educational Blogging: A Case Study from Library & Information Science

    Science.gov (United States)

    Rebmann, Kristen Radsliff; Clark, Camden Bernard

    2017-01-01

    This article charts the development of activities for online graduate students in library and information science. Project goals include helping students develop competencies in understanding open access publishing, synthesizing research in the field, and engaging in scholarly communication via collaborative educational blogging. Using a design…

  6. The ecology of the open practitioner: a conceptual framework for open research

    OpenAIRE

    Adrian Stagg

    2017-01-01

    Open Educational Practices (OEP) have gained traction internationally over the last fifteen years, with individuals, institutions, and governments increasingly interested in the affordances of openness. Whilst initiatives, policies, and support mechanisms are evident, there is an ever-present danger of localised contexts being unintentionally unrecognised, which has a negative effect on mainstreaming the practice sustainably. This paper presents a conceptual framework for open research based ...

  7. Data-driven engineering design research: Opportunities using open data

    DEFF Research Database (Denmark)

    Parraguez Ruiz, Pedro; Maier, Anja

    2017-01-01

    the already available and continuously growing body of open data sources to create opportunities for research in Engineering Design. Insights are illustrated by an examination of two examples: a study of open source software repositories and an analysis of open business registries in the cleantech industry....... We conclude with a discussion about the limitations, challenges and risks of using open data in Engineering Design research and practice.......Engineering Design research relies on quantitative and qualitative data to describe design-related phenomena and prescribe improvements for design practice. Given data availability, privacy requirements and other constraints, most empirical data used in Engineering Design research can be described...

  8. Open-field mouse brain PET: design optimisation and detector characterisation.

    Science.gov (United States)

    Kyme, Andre Z; Judenhofer, Martin S; Gong, Kuang; Bec, Julien; Selfridge, Aaron; Du, Junwei; Qi, Jinyi; Cherry, Simon R; Meikle, Steven R

    2017-07-13

    'Open-field' PET, in which an animal is free to move within an enclosed space during imaging, is a very promising advance for neuroscientific research. It provides a key advantage over conventional imaging under anesthesia by enabling functional changes in the brain to be correlated with an animal's behavioural response to environmental or pharmacologic stimuli. Previously we have demonstrated the feasibility of open-field imaging of rats using motion compensation techniques applied to a commercially available PET scanner. However, this approach of 'retro-fitting' motion compensation techniques to an existing system is limited by the inherent geometric and performance constraints of the system. The goal of this project is to develop a purpose-built PET scanner with geometry, motion tracking and imaging performance tailored and optimised for open-field imaging of the mouse brain. The design concept is a rail-based sliding tomograph which moves according to the animal's motion. Our specific aim in this work was to evaluate candidate scanner designs and characterise the performance of a depth-of-interaction detector module for the open-field system. We performed Monte Carlo simulations to estimate and compare the sensitivity and spatial resolution performance of four scanner geometries: a ring, parallel plate, and two box variants. Each system was based on a detector block consisting of a 23  ×  23 array of 0.785  ×  0.785  ×  20 mm 3 LSO crystals (overall dim. 19.6  ×  19.6  ×  20 mm). We found that a DoI resolution capability of 3 mm was necessary to achieve approximately uniform sub-millimetre spatial resolution throughout the FoV for all scanners except the parallel-plate geometry. With this DoI performance, the sensitivity advantage afforded by the box geometry with overlapping panels (16% peak absolute sensitivity, a 36% improvement over the ring design) suggests this unconventional design is best suited for

  9. Identification of QLTs involved in open-field behavior in young and ad laying hens

    NARCIS (Netherlands)

    Buitenhuis, A.J.; Rodenburg, T.B.; Siwek, M.Z.; Cornelissen, S.J.B.; Nieuwland, M.G.B.; Crooijmans, R.P.M.A.; Groenen, M.A.M.; Koene, P.; Bovenhuis, H.; Poel, van der J.J.

    2004-01-01

    Line differences for open-field behavior in chickens have been observed, and it has been shown that this behavior has a genetic component. The aim of this study was to detect quantitative trait loci (QTL) involved in open-field behavior. For this purpose, open-field behavior was studied at 5 and 29

  10. In situ analysis of soil at an open burning/open detonation disposal facility: J-Field, Aberdeen Proving Ground, Maryland

    International Nuclear Information System (INIS)

    Martino, L.; Cho, E.; Wrobel, J.

    1994-01-01

    Investigators have used a field-portable X-Ray Fluorescence (XRF) Analyzer to screen soils for a suite of metals indicative of the open burning and open detonation (OB/OD) activities that occurred at the J-Field site at Aberdeen Proving Ground, Maryland. The field XRF results were incorporated into a multiphase investigation of contaminants at the Toxic Burning Pits Area of Concern at J-Field. The authors determined that the field-portable XRF unit used for the study and the general concept of field XRF screening are invaluable tools for investigating an OB/OD site where intrusive sampling techniques could present unacceptable hazards to site workers

  11. UV / IR mixing in noncommutative field theory via open string loops

    International Nuclear Information System (INIS)

    Kiem, Youngjai; Lee, Sangmin

    2000-01-01

    We explicitly evaluate one-loop (annulus) planar and nonplanar open string amplitudes in the presence of the background NS-NS two-form field. In the decoupling limit of Seiberg and Witten, we find that the nonplanar string amplitudes reproduce the UV/IR mixing of noncommutative field theories. In particular, the investigation of the UV regime of the open string amplitudes shows that certain IR closed string degrees of freedom survive the decoupling limit as previously predicted from the noncommutative field theory analysis. These degrees of freedom are responsible for the quadratic, linear and logarithmic IR singularities when the D-branes embedded in space-time have the codimension zero, one and two, respectively. The analysis is given for both bosonic and supersymmetric open strings

  12. Pushing Firm Boundaries through Research and Open Innovation

    DEFF Research Database (Denmark)

    Borup Lynggaard, Aviaja

    2011-01-01

    In this paper we will exemplify open innovation through a university-industry collaboration called Mobile Home Center (MHC). We will demonstrate how the model by Chesbrough can be used as a tool for mapping out a research process and furthermore illustrate what kind of outcast such project can...... provide into the company and bring forward the effect it has inside a company when performing open innovation together with research partners. We seek to bring forward how performing university-research collaboration can also change the practices inside a company and thus push the firm boundaries in new...... directions. Rather than looking at the firm as something static we will demonstrate how Chesbrough’s model on Open Innovation can be used to illustrate the dynamics of a company’s boundaries through Open Innovation....

  13. The importance of open data and software: Is energy research lagging behind?

    International Nuclear Information System (INIS)

    Pfenninger, Stefan; DeCarolis, Joseph; Hirth, Lion; Quoilin, Sylvain; Staffell, Iain

    2017-01-01

    Energy policy often builds on insights gained from quantitative energy models and their underlying data. As climate change mitigation and economic concerns drive a sustained transformation of the energy sector, transparent and well-founded analyses are more important than ever. We assert that models and their associated data must be openly available to facilitate higher quality science, greater productivity through less duplicated effort, and a more effective science-policy boundary. There are also valid reasons why data and code are not open: ethical and security concerns, unwanted exposure, additional workload, and institutional or personal inertia. Overall, energy policy research ostensibly lags behind other fields in promoting more open and reproducible science. We take stock of the status quo and propose actionable steps forward for the energy research community to ensure that it can better engage with decision-makers and continues to deliver robust policy advice in a transparent and reproducible way. - Highlights: • Energy models and data are an important basis for energy policy. • Opening energy models and data benefits actors inside and outside of academia. • Reasons include higher quality science, greater productivity and recognition. • Private barriers must be overcome, but the private and public gains outweigh them. • We provide advice on how and why the community could coordinate a shift to openness.

  14. Easy research data handling with an OpenEarth DataLab for geo-monitoring research

    Science.gov (United States)

    Vanderfeesten, Maurice; van der Kuil, Annemiek; Prinčič, Alenka; den Heijer, Kees; Rombouts, Jeroen

    2015-04-01

    OpenEarth DataLab is an open source-based collaboration and processing platform to enable streamlined research data management from raw data ingest and transformation to interoperable distribution. It enables geo-scientists to easily synchronise, share, compute and visualise the dynamic and most up-to-date research data, scripts and models in multi-stakeholder geo-monitoring programs. This DataLab is developed by the Research Data Services team of TU Delft Library and 3TU.Datacentrum together with coastal engineers of Delft University of Technology and Deltares. Based on the OpenEarth software stack an environment has been developed to orchestrate numerous geo-related open source software components that can empower researchers and increase the overall research quality by managing research data; enabling automatic and interoperable data workflows between all the components with track & trace, hit & run data transformation processing in cloud infrastructure using MatLab and Python, synchronisation of data and scripts (SVN), and much more. Transformed interoperable data products (KML, NetCDF, PostGIS) can be used by ready-made OpenEarth tools for further analyses and visualisation, and can be distributed via interoperable channels such as THREDDS (OpenDAP) and GeoServer. An example of a successful application of OpenEarth DataLab is the Sand Motor, an innovative method for coastal protection in the Netherlands. The Sand Motor is a huge volume of sand that has been applied along the coast to be spread naturally by wind, waves and currents. Different research disciplines are involved concerned with: weather, waves and currents, sand distribution, water table and water quality, flora and fauna, recreation and management. Researchers share and transform their data in the OpenEarth DataLab, that makes it possible to combine their data and to see influence of different aspects of the coastal protection on their models. During the project the data are available only for the

  15. 3D for the people: multi-camera motion capture in the field with consumer-grade cameras and open source software

    Directory of Open Access Journals (Sweden)

    Brandon E. Jackson

    2016-09-01

    Full Text Available Ecological, behavioral and biomechanical studies often need to quantify animal movement and behavior in three dimensions. In laboratory studies, a common tool to accomplish these measurements is the use of multiple, calibrated high-speed cameras. Until very recently, the complexity, weight and cost of such cameras have made their deployment in field situations risky; furthermore, such cameras are not affordable to many researchers. Here, we show how inexpensive, consumer-grade cameras can adequately accomplish these measurements both within the laboratory and in the field. Combined with our methods and open source software, the availability of inexpensive, portable and rugged cameras will open up new areas of biological study by providing precise 3D tracking and quantification of animal and human movement to researchers in a wide variety of field and laboratory contexts.

  16. Open Access Publishing in Indian Premier Research Institutions

    Science.gov (United States)

    Bhat, Mohammad Hanief

    2009-01-01

    Introduction: Publishing research findings in open access journals is a means of enhancing visibility and consequently increasing the impact of publications. This study provides an overview of open access publishing in premier research institutes of India. Method: The publication output of each institution from 2003 to 2007 was ascertained through…

  17. The relation between open-field and emergence tests in a hyperactive mouse model.

    Science.gov (United States)

    Lalonde, R; Strazielle, C

    2009-12-01

    The relation between open-field and emergence tests was examined in mice with idiopathic hypertension. Spontaneous hypertensive mice (SHM) crossed more segments and reared more often in the open-field than normotensive controls at both age levels. In contrast, grooming episodes decreased only in the older SHM cohort. While young SHM emerged more quickly from a toy object only partially, complete emergence was faster only in the older SHM cohort. In the entire series, open-field segments were inversely correlated with 2- and 4-paw emergence latencies. There was also an inverse correlation between rears and 2-paw emergence but a positive correlation between grooming episodes and both types of emergence. In view of its association with open-field activity, the emergence test may have value in screening potential ADHD therapies.

  18. Open cyberGIS software for geospatial research and education in the big data era

    Science.gov (United States)

    Wang, Shaowen; Liu, Yan; Padmanabhan, Anand

    CyberGIS represents an interdisciplinary field combining advanced cyberinfrastructure, geographic information science and systems (GIS), spatial analysis and modeling, and a number of geospatial domains to improve research productivity and enable scientific breakthroughs. It has emerged as new-generation GIS that enable unprecedented advances in data-driven knowledge discovery, visualization and visual analytics, and collaborative problem solving and decision-making. This paper describes three open software strategies-open access, source, and integration-to serve various research and education purposes of diverse geospatial communities. These strategies have been implemented in a leading-edge cyberGIS software environment through three corresponding software modalities: CyberGIS Gateway, Toolkit, and Middleware, and achieved broad and significant impacts.

  19. Open cyberGIS software for geospatial research and education in the big data era

    Directory of Open Access Journals (Sweden)

    Shaowen Wang

    2016-01-01

    Full Text Available CyberGIS represents an interdisciplinary field combining advanced cyberinfrastructure, geographic information science and systems (GIS, spatial analysis and modeling, and a number of geospatial domains to improve research productivity and enable scientific breakthroughs. It has emerged as new-generation GIS that enable unprecedented advances in data-driven knowledge discovery, visualization and visual analytics, and collaborative problem solving and decision-making. This paper describes three open software strategies–open access, source, and integration–to serve various research and education purposes of diverse geospatial communities. These strategies have been implemented in a leading-edge cyberGIS software environment through three corresponding software modalities: CyberGIS Gateway, Toolkit, and Middleware, and achieved broad and significant impacts.

  20. Solar Open Flux Migration from Pole to Pole: Magnetic Field Reversal.

    Science.gov (United States)

    Huang, G-H; Lin, C-H; Lee, L C

    2017-08-25

    Coronal holes are solar regions with low soft X-ray or low extreme ultraviolet intensities. The magnetic fields from coronal holes extend far away from the Sun, and thus they are identified as regions with open magnetic field lines. Coronal holes are concentrated in the polar regions during the sunspot minimum phase, and spread to lower latitude during the rising phase of solar activity. In this work, we identify coronal holes with outward and inward open magnetic fluxes being in the opposite poles during solar quiet period. We find that during the sunspot rising phase, the outward and inward open fluxes perform pole-to-pole trans-equatorial migrations in opposite directions. The migration of the open fluxes consists of three parts: open flux areas migrating across the equator, new open flux areas generated in the low latitude and migrating poleward, and new open flux areas locally generated in the polar region. All three components contribute to the reversal of magnetic polarity. The percentage of contribution from each component is different for different solar cycle. Our results also show that the sunspot number is positively correlated with the lower-latitude open magnetic flux area, but negatively correlated with the total open flux area.

  1. A proposal for an effective interacting field theory of open and closed strings

    International Nuclear Information System (INIS)

    Baulieu, L.; Grossman, B.

    1987-01-01

    We propose the use of the reggeon-pomeron vertex to obtain an effective field theory for open and closed strings. We suggest that closed string fields are necessary in order to go off-shell in an open string field theory. We then find that the closed string fields satisfy the Virasoro constraints (including equal number of left and right movers) in an appropriate choice of gauge. (orig.)

  2. Plasma opening switch with extrinsic magnetic field

    CERN Document Server

    Dolgachev, G; Maslennikov, D

    2001-01-01

    Summary form only given, as follows. We have demonstrated in series of experiments that plasma opening switch (POS) switching voltage (UPOS) is defined by energy density (w) deposited in the POS plasma. If we then consider a plasma erosion mainly responsible for the effect of POS switching (the erosion effect could be described by Hall or Child-Langmuir models) the energy density (w) could be measured as a function of a system "macro-parameter" such as the initial charging voltage of the capacity storage system (the Marx pulsed voltage generator) UMarx. The POS voltage in this case could be given by UPOS"aw=aUMarx4/7, where a is a constant. This report demonstrates that for the high-impedance POS which has limited charge density transferred through the POS plasma a"2.5 (MV3/7) with no external magnetic field applied. The use of the extrinsic magnetic field allows to increase a up to 3.6 (MV3/7) and to achieve higher voltages at the opening phase - UPOS=3.6UMarx4/7. To verify this approach set of experimental ...

  3. Open science versus commercialization: a modern research conflict?

    Science.gov (United States)

    Caulfield, Timothy; Harmon, Shawn He; Joly, Yann

    2012-02-27

    Efforts to improve research outcomes have resulted in genomic researchers being confronted with complex and seemingly contradictory instructions about how to perform their tasks. Over the past decade, there has been increasing pressure on university researchers to commercialize their work. Concurrently, they are encouraged to collaborate, share data and disseminate new knowledge quickly (that is, to adopt an open science model) in order to foster scientific progress, meet humanitarian goals, and to maximize the impact of their research. We present selected guidelines from three countries (Canada, United States, and United Kingdom) situated at the forefront of genomics to illustrate this potential policy conflict. Examining the innovation ecosystem and the messages conveyed by the different policies surveyed, we further investigate the inconsistencies between open science and commercialization policies. Commercialization and open science are not necessarily irreconcilable and could instead be envisioned as complementary elements of a more holistic innovation framework. Given the exploratory nature of our study, we wish to point out the need to gather additional evidence on the coexistence of open science and commercialization policies and on its impact, both positive and negative, on genomics academic research.

  4. A Human Open Field Test Reveals Thigmotaxis Related to Agoraphobic Fear.

    Science.gov (United States)

    Walz, Nora; Mühlberger, Andreas; Pauli, Paul

    2016-09-01

    Thigmotaxis refers to a specific behavior of animals (i.e., to stay close to walls when exploring an open space). Such behavior can be assessed with the open field test (OFT), which is a well-established indicator of animal fear. The detection of similar open field behavior in humans may verify the translational validity of this paradigm. Enhanced thigmotaxis related to anxiety may suggest the relevance of such behavior for anxiety disorders, especially agoraphobia. A global positioning system was used to analyze the behavior of 16 patients with agoraphobia and 18 healthy individuals with a risk for agoraphobia (i.e., high anxiety sensitivity) during a human OFT and compare it with appropriate control groups (n = 16 and n = 19). We also tracked 17 patients with agoraphobia and 17 control participants during a city walk that involved walking through an open market square. Our human OFT triggered thigmotaxis in participants; patients with agoraphobia and participants with high anxiety sensitivity exhibited enhanced thigmotaxis. This behavior was evident in increased movement lengths along the wall of the natural open field and fewer entries into the center of the field despite normal movement speed and length. Furthermore, participants avoided passing through the market square during the city walk, indicating again that thigmotaxis is related to agoraphobia. This study is the first to our knowledge to verify the translational validity of the OFT and to reveal that thigmotaxis, an evolutionarily adaptive behavior shown by most species, is related to agoraphobia, a pathologic fear of open spaces, and anxiety sensitivity, a risk factor for agoraphobia. Copyright © 2016 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

  5. THE TOPOLOGICAL CHANGES OF SOLAR CORONAL MAGNETIC FIELDS. II. THE RECLOSING OF AN OPENED FIELD

    International Nuclear Information System (INIS)

    Low, B. C.; Janse, A. M.

    2009-01-01

    This is a study of the spontaneous formation of current sheets responding to the closing of an opened magnetic field by resistive reconnection in an electrically, highly conducting atmosphere outside a unit sphere. Pairs of initial-final equilibrium states are calculated explicitly, taking the field to be composed of three systems of untwisted flux in both states. In the initial state, two of the three flux systems are closed potential fields whereas the third system contains an equilibrium current sheet that keeps the potential fields on its two sides globally open. The final state is an everywhere potential field, with all three flux systems closed, produced by the resistive dissipation of the current sheet in the initial state. The unit sphere is taken to be a rigid, perfectly conducting wall during reconnection, so that the normal flux distribution is unchanged on the unit sphere. Field solutions subject to this unchanging boundary condition are obtained with and without the assumption of axisymmetry. The mathematical model has been designed to show that the topological changes produced by the current-sheet dissipation are simple under axisymmetry but radically different in the absence of axisymmetry, a fundamental point established in the first paper of this series. In the general case, the topological changes imply that other current sheets must have formed. Some of these current sheets form on the separatrix flux surfaces of the multipolar field. Others form throughout the closed-flux systems induced by volumetric changes. The opening and reclosing of magnetic fields during a solar coronal mass ejection may produce a multitude of current sheets not previously anticipated in the current understanding of this phenomenon. Basic to this study is a general topological property of magnetic flux tubes treated separately in the Appendix.

  6. Software developed by research vs. Freedom of information in EU (open access and open data)

    Czech Academy of Sciences Publication Activity Database

    Kolman, Jiří

    2014-01-01

    Roč. 8, č. 2 (2014), s. 183-198 ISSN 1802-5951 Institutional support: RVO:67179843 Keywords : cooperation of public research institutions and private partners * freedom of information in the EU * open access * open data * research and development * software Subject RIV: AG - Legal Sciences

  7. Air pollutant emissions from rice straw open field burning in India, Thailand and the Philippines

    International Nuclear Information System (INIS)

    Gadde, Butchaiah; Bonnet, Sebastien; Menke, Christoph; Garivait, Savitri

    2009-01-01

    Rice is a widely grown crop in Asia. China (30%) and India (21%) contribute to about half of the world's total rice production. In this study, three major rice-producing countries in Asia are considered, India, Thailand and the Philippines (the later two contributing 4% and 2% of the world's rice production). Rice straw is one of the main field based residues produced along with this commodity and its applications vary widely in the region. Although rice production practises vary from one country to another, open burning of straw is a common practice in these countries. In this study, an approach was followed aiming at (a) determining the quantity of rice straw being subject to open field burning in those countries, (b) congregating pollutant specific emissions factors for rice straw burning, and (c) quantifying the resulting air pollutant emissions. Uncertainties in the results obtained as compared to a global approach are also discussed. - This research work contributes to enhance scientific knowledge for estimating air pollutant emissions from open burning of crop residues and improve emission results accuracy.

  8. Singular surfaces in the open field line region of a diverted tokamak

    International Nuclear Information System (INIS)

    Reiman, A.

    1996-01-01

    The structure of the open field lines of a slightly nonaxisymmetric, poloidally diverted tokamak is explored by numerical integration of the field line equations for a simple model field. In practice, the nonaxisymmetry could be produced self-consistently by the nonlinear evolution of a free-boundary magnetohydrodynamic (MHD) mode, or it could be produced by field errors, or it could be imposed externally by design. In the presence of a nonaxisymmetric perturbation, the tokamak is shown to develop open field line regions of differing topology separated by singular surfaces. It is argued that the singular surfaces can be expected to play a role analogous to that of rational toroidal flux surfaces, in terms of constraining ideal MHD perturbations and thus constraining the free-energy that can be tapped by ideal MHD instabilities. The possibility of active control of free-boundary instabilities by means of currents driven on the open singular surfaces, which are directly accessible from the divertor plates, is discussed. copyright 1996 American Institute of Physics

  9. Behavioral and locomotor measurements using an open field activity monitoring system for skeletal muscle diseases.

    Science.gov (United States)

    Tatem, Kathleen S; Quinn, James L; Phadke, Aditi; Yu, Qing; Gordish-Dressman, Heather; Nagaraju, Kanneboyina

    2014-09-29

    The open field activity monitoring system comprehensively assesses locomotor and behavioral activity levels of mice. It is a useful tool for assessing locomotive impairment in animal models of neuromuscular disease and efficacy of therapeutic drugs that may improve locomotion and/or muscle function. The open field activity measurement provides a different measure than muscle strength, which is commonly assessed by grip strength measurements. It can also show how drugs may affect other body systems as well when used with additional outcome measures. In addition, measures such as total distance traveled mirror the 6 min walk test, a clinical trial outcome measure. However, open field activity monitoring is also associated with significant challenges: Open field activity measurements vary according to animal strain, age, sex, and circadian rhythm. In addition, room temperature, humidity, lighting, noise, and even odor can affect assessment outcomes. Overall, this manuscript provides a well-tested and standardized open field activity SOP for preclinical trials in animal models of neuromuscular diseases. We provide a discussion of important considerations, typical results, data analysis, and detail the strengths and weaknesses of open field testing. In addition, we provide recommendations for optimal study design when using open field activity in a preclinical trial.

  10. Management of whitefly-transmitted viruses in open-field production systems.

    Science.gov (United States)

    Lapidot, Moshe; Legg, James P; Wintermantel, William M; Polston, Jane E

    2014-01-01

    Whiteflies are a key pest of crops in open-field production throughout the tropics and subtropics. This is due in large part to the long and diverse list of devastating plant viruses transmitted by these vectors. Open-field production provides many challenges to manage these viruses and in many cases adequate management has not been possible. Diseases caused by whitefly-transmitted viruses have become limiting factors in open-field production of a wide range of crops, i.e., bean golden mosaic disease in beans, tomato yellow leaf curl disease in tomato, cassava mosaic disease and cassava brown streak disease in cassava, and cotton leaf crumple disease in cotton. While host resistance has proven to be the most cost-effective management solution, few examples of host resistance have been developed to date. The main strategy to limit the incidence of virus-infected plants has been the application of insecticides to reduce vector populations aided to some extent by the use of selected cultural practices. However, due to concerns about the effect of insecticides on pollinators, consumer demand for reduced pesticide use, and the ability of the whitefly vectors to develop insecticide-resistance, there is a growing need to develop and deploy strategies that do not rely on insecticides. The reduction in pesticide use will greatly increase the need for genetic resistance to more viruses in more crop plants. Resistance combined with selected IPM strategies could become a viable means to increase yields in crops produced in open fields despite the presence of whitefly-transmitted viruses.

  11. A covariant open bosonic string field theory including the endpoint and middlepoint interaction

    International Nuclear Information System (INIS)

    Liu, B.G.; Northwest Univ., Xian; Chen, Y.X.

    1988-01-01

    Extending the usual endpoint and midpoint interactions, we introduce numerous kinds of interactions, labelled by a parameter λ and obtain a non-commutative and associative string field algebra by adding up all interactions. With this algebra we develop a covariant open bosonic string field theory, which reduces to Witten's open bosonic string field theory under a special string length choice. (orig.)

  12. Innovation, research and best practice in open and distance education

    Directory of Open Access Journals (Sweden)

    Inés Gil-Jaurena

    2015-11-01

    Full Text Available This last 2015 issue of Open Praxis brings together eight articles. First five contributions were awarded an ICDE prize for Innovation and Best Practice in the field of open and distance education (second edition. The three last papers were submitted to Open Praxis following the regular process. 

  13. Variations in depth-dose data between open and wedge fields for 4-MV x-rays

    International Nuclear Information System (INIS)

    Sewchand, W.; Khan, F.M.; Williamson, J.

    1978-01-01

    Central-axis depth-dose data for 4-MV x rays, including tissue-maximum ratios, were measured for wedge fields. Comparison with corresponding open-field data revealed differences in magnitude which increased with depth, field size, and wedge thickness. However, phantom scatter correction factors for the wedge fields differed less than 1% from corresponding open-field factors. The differences in central-axis percent depth doses between the two types of fields indicate beam hardening by the wedge filter. This study also implies that the derivation of tissue-maximum ratios from central-axis percent depth is as valid for wedge as for open fields

  14. Preliminary experiment research of explosively driven opening switch

    International Nuclear Information System (INIS)

    Li Xiaolin; Chen Dongqun; Li Da; Cao Shengguang; Chen Yingcong

    2010-01-01

    In pulse power technology field, many loads require high current pulse with fast risetime, but sometimes, the common high current pulse powers don't satisfy request, thus there need pulse erection switches of sorts to shorten pulse risetime. Explosively driven opening switch (EDOS) is a good choice, it has simple structure and excellent performance, the primary parameters of EDOS are opening time, opening resistance, opening current and dissipation energy, which determine its performance and range for applications. For this, two kinds of EDOS are designed and manufactured, in the later experiments, the power supply is a 200 μF capacitor and the conductor is 0.03 mm copper foil, the results indicate that the two kinds of EDOS have good performance, the opening time is about 1-3 μs, the opening resistance is about 1-2 Ω, the opening current is about 24-31 kA and the average dissipation energy is about 0.125-0.34 kJ per groove, the capability of conduction current is adjusted by the thickness of conductor along with different opening current. (authors)

  15. A handheld open-field infant keratometer (an american ophthalmological society thesis).

    Science.gov (United States)

    Miller, Joseph M

    2010-12-01

    To design and evaluate a new infant keratometer that incorporates an unobstructed view of the infant with both eyes (open-field design). The design of the open-field infant keratometer is presented, and details of its construction are given. The design incorporates a single-ring keratoscope for measurement of corneal astigmatism over a 4-mm region of the cornea and includes a rectangular grid target concentric within the ring to allow for the study of higher-order aberrations of the eye. In order to calibrate the lens and imaging system, a novel telecentric test object was constructed and used. The system was bench calibrated against steel ball bearings of known dimensions and evaluated for accuracy while being used in handheld mode in a group of 16 adult cooperative subjects. It was then evaluated for testability in a group of 10 infants and toddlers. Results indicate that while the device achieved the goal of creating an open-field instrument containing a single-ring keratoscope with a concentric grid array for the study of higher-order aberrations, additional work is required to establish better control of the vertex distance. The handheld open-field infant keratometer demonstrates testability suitable for the study of infant corneal astigmatism. Use of collimated light sources in future iterations of the design must be incorporated in order to achieve the accuracy required for clinical investigation.

  16. Antioxidant effects of nerolidol in mice hippocampus after open field test.

    Science.gov (United States)

    Nogueira Neto, José Damasceno; de Almeida, Antonia Amanda Cardoso; da Silva Oliveira, Johanssy; Dos Santos, Pauline Sousa; de Sousa, Damião Pergentino; de Freitas, Rivelilson Mendes

    2013-09-01

    The aim of this study was to evaluate the neuroprotective effects of nerolidol in mice hippocampus against oxidative stress in neuronal cells compared to ascorbic acid (positive control) as well as evaluated the nerolidol sedative effects by open field test compared to diazepam (positive control). Thirty minutes prior to behavioral observation on open field test, mice were intraperitoneally treated with vehicle, nerolidol (25, 50 and 75 mg/kg), diazepam (1 mg/kg) or ascorbic acid (250 mg/kg). To clarify the action mechanism of of nerolidol on oxidative stress in animals subjected to the open field test, Western blot analysis of Mn-superoxide dismutase and catalase in mice hippocampus were performed. In nerolidol group, there was a significant decrease in lipid peroxidation and nitrite levels when compared to negative control (vehicle). However, a significant increase was observed in superoxide dismutase and catalase activities in this group when compared to the other groups. Vehicle, diazepam, ascorbic acid and nerolidol groups did not affected Mn-superoxide dismutase, catalase mRNA or protein levels. Our findings strongly support the hypothesis that oxidative stress occurs in hippocampus. Nerolidol showed sedative effects in animals subjected to the open field test. Oxidative process plays a crucial role on neuronal pathological consequence, and implies that antioxidant effects could be achieved using this sesquiterpene.

  17. Scaling law in free walking of mice in circular open fields of various diameters.

    Science.gov (United States)

    Shoji, Hiroto

    2016-03-01

    Open-field tests are routinely used to study locomotor activity in rodents. I studied the effects of apparatus size on rodent locomotor activity, specifically with respect to how resting and walking periods are interwoven. I explored the open-field behavior of mice utilizing circular open fields of various diameters. When the diameter of the test apparatus was greater than 75 cm, the durations of the resting and moving periods of free walking behavior obeyed bounded power-law distribution functions. I found that the properties of the scaling exponents and model selection became similar for test apparatus diameters greater than 75 cm. These results can provide a guide for the selection of the size of the test apparatus for use in the study of the open-field behavior of rodents.

  18. Singular surfaces in the open field line region of a diverted tokamak

    International Nuclear Information System (INIS)

    Reiman, A.

    1995-05-01

    The structure of the open field lines of a slightly nonaxisymmetric, poloidally diverted tokamak is explored by numerical integration of the field line equations for a simple model field. In practice, the nonaxisymmetry could be produced self-consistently by the nonlinear evolution of a free-boundary MHD mode, or it could be produced by field errors, or it could be imposed externally by design. In the presence of a nonaxisymmetric perturbation, the tokamak is shown to develop open field line regions of differing topology separated by singular surfaces. It is argued that the singular surfaces can be expected to play a role analogous to that of rational toroidal flux surfaces, in terms of constraining ideal MHD perturbations and thus constraining the free-energy that can be tapped by ideal MHD instabilities. The possibility of active control of free-boundary instabilities by means of currents driven on the open singular surfaces, which are directly accessible from the divertor plates, is discussed. Also discussed is the possibility of early detection of imminent disruptions through localized measurement of the singular surface currents

  19. Physical states at the tachyonic vacuum of open string field theory

    International Nuclear Information System (INIS)

    Giusto, S.; Imbimbo, C.

    2004-01-01

    We illustrate a method for computing the number of physical states of open string theory at the stable tachyonic vacuum in level truncation approximation. The method is based on the analysis of the gauge-fixed open string field theory quadratic action that includes Fadeev-Popov ghost string fields. Computations up to level 9 in the scalar sector are consistent with Sen's conjecture about the absence of physical open string states at the tachyonic vacuum. We also derive a long exact cohomology sequence that relates relative and absolute cohomologies of the BRS operator at the non-perturbative vacuum. We use this exact result in conjunction with our numerical findings to conclude that the higher ghost number non-perturbative BRS cohomologies are non-empty

  20. Economies: An Open Access Journal for the Field of Development Macroeconomics

    Directory of Open Access Journals (Sweden)

    Ralf Fendel

    2013-01-01

    Full Text Available Economies (ISSN 2227-7099 is a new international, peer-reviewed open access journal for the academic fields of development economics and macroeconomics. While the latter seems to be clearly defined, development economics is not, because it is related to nearly all traditional economic sub-disciplines such as macroeconomics, international trade and finance, as well as microeconomics and public finance. Typically, academic field journals of development economics cover all those economic sub-disciplines. Economies instead focuses mainly on the macroeconomic perspective of economic development and it intends to publish academic research that is of strong macroeconomic policy relevance. In general, contributions in Economies should foster understanding of the macroeconomic process of economic development, with the process of development not exclusively being reserved to what we typically call developing countries. Also, the group of developed economies is still developing in the sense of improving their living standards further.

  1. Open algebraic surfaces

    CERN Document Server

    Miyanishi, Masayoshi

    2000-01-01

    Open algebraic surfaces are a synonym for algebraic surfaces that are not necessarily complete. An open algebraic surface is understood as a Zariski open set of a projective algebraic surface. There is a long history of research on projective algebraic surfaces, and there exists a beautiful Enriques-Kodaira classification of such surfaces. The research accumulated by Ramanujan, Abhyankar, Moh, and Nagata and others has established a classification theory of open algebraic surfaces comparable to the Enriques-Kodaira theory. This research provides powerful methods to study the geometry and topology of open algebraic surfaces. The theory of open algebraic surfaces is applicable not only to algebraic geometry, but also to other fields, such as commutative algebra, invariant theory, and singularities. This book contains a comprehensive account of the theory of open algebraic surfaces, as well as several applications, in particular to the study of affine surfaces. Prerequisite to understanding the text is a basic b...

  2. Open-field mouse brain PET: design optimisation and detector characterisation

    Science.gov (United States)

    Kyme, Andre Z.; Judenhofer, Martin S.; Gong, Kuang; Bec, Julien; Selfridge, Aaron; Du, Junwei; Qi, Jinyi; Cherry, Simon R.; Meikle, Steven R.

    2017-08-01

    Open-field’ PET, in which an animal is free to move within an enclosed space during imaging, is a very promising advance for neuroscientific research. It provides a key advantage over conventional imaging under anesthesia by enabling functional changes in the brain to be correlated with an animal’s behavioural response to environmental or pharmacologic stimuli. Previously we have demonstrated the feasibility of open-field imaging of rats using motion compensation techniques applied to a commercially available PET scanner. However, this approach of ‘retro-fitting’ motion compensation techniques to an existing system is limited by the inherent geometric and performance constraints of the system. The goal of this project is to develop a purpose-built PET scanner with geometry, motion tracking and imaging performance tailored and optimised for open-field imaging of the mouse brain. The design concept is a rail-based sliding tomograph which moves according to the animal’s motion. Our specific aim in this work was to evaluate candidate scanner designs and characterise the performance of a depth-of-interaction detector module for the open-field system. We performed Monte Carlo simulations to estimate and compare the sensitivity and spatial resolution performance of four scanner geometries: a ring, parallel plate, and two box variants. Each system was based on a detector block consisting of a 23  ×  23 array of 0.785  ×  0.785  ×  20 mm3 LSO crystals (overall dim. 19.6  ×  19.6  ×  20 mm). We found that a DoI resolution capability of 3 mm was necessary to achieve approximately uniform sub-millimetre spatial resolution throughout the FoV for all scanners except the parallel-plate geometry. With this DoI performance, the sensitivity advantage afforded by the box geometry with overlapping panels (16% peak absolute sensitivity, a 36% improvement over the ring design) suggests this unconventional design is best

  3. One-loop masses of open-string scalar fields in string theory

    International Nuclear Information System (INIS)

    Kitazawa, Noriaki

    2008-01-01

    In phenomenological models with D-branes, there are in general open-string massless scalar fields, in addition to closed-string massless moduli fields corresponding to the compactification. It is interesting to focus on the fate of such scalar fields in models with broken supersymmetry, because no symmetry forbids their masses. The one-loop effect may give non-zero masses to them, and in some cases mass squared may become negative, which means the radiative gauge symmetry breaking. In this article we investigate and propose a simple method for calculating the one-loop corrections using the boundary state formalism. There are two categories of massless open-string scalar fields. One consists the gauge potential fields corresponding to compactified directions, which can be understood as scalar fields in uncompactified space-time (related with Wilson line degrees of freedom). The other consists 'gauge potential fields' corresponding to transverse directions of D-brane, which emerge as scalar fields in D-brane world-volume (related with brane moduli fields). The D-brane boundary states with constant backgrounds of these scalar fields are constructed, and one-loop scalar masses are calculated in the closed string picture. Explicit calculations are given in the following four concrete models: one D25-brane with a circle compactification in bosonic string theory, one D9-brane with a circle compactification in superstring theory, D3-branes at a supersymmetric C 3 /Z 3 orbifold singularity, and a model of brane supersymmetry breaking with D3-branes and anti-D7-branes at a supersymmetric C 3 /Z 3 orbifold singularity. We show that the sign of the mass squared has a strong correlation with the sign of the related open-string one-loop vacuum amplitude.

  4. New frontiers in open innovation

    CERN Document Server

    Vanhaverbeke, Wim; West, Joel

    2014-01-01

    Companies have to innovate to stay competitive, and they have to collaborate with other organizations to innovate effectively. Although the benefits of "open innovation" have been described in detail before, mechanisms underlying how companies can be successful "open innovators" have not be understood well. A growing community of innovation management researchers started to develop different frameworks to understand open innovation in a more systematic way. This book provides a thorough examination of research conducted to date on open innovation, as well as a comprehensive overview of what will be the most important, most promising and most relevant research topics in this area during the next decade. "Open Innovation: Researching a new paradigm" (OUP 2006) was the first initiative to bring open innovation closer to the academic community. Open innovation research has since then been growing in an exponential way and research has evolved in different and unexpected directions. As the research field is growin...

  5. Stakeholder values and ecosystems in developing open access to research data.

    Science.gov (United States)

    Wessels, Bridgette; Sveinsdottir, Thordis; Smallwood, Rod

    2014-05-01

    One aspect of understanding how to develop open access to research data is to understand the values of stakeholders in the emerging open data ecosystem. The EU FP7 funded project Policy RECommendations for Open Access to Research Data in Europe (RECODE) (Grant Agreement No: 321463) undertook such research to identify stakeholder values and mapped the emerging ecosystem. In this paper we outline and discuss the findings of this research. We address three key objectives, which are: (a) the identification and mapping of the diverse range of stakeholder values in Open Access data and data dissemination and preservation; (b) mapping stakeholder values on to research ecosystems using case studies from different disciplinary perspectives; and (c) evaluate and identify good practice in addressing conflicting value chains and stakeholder fragmentation. The research was structured on three related actions: (a) an analysis of policy and related documents and protocols, in order to map the formal expression of values and motivations; (b) conducting five case studies in particle physics, health sciences, bioengineering, environmental research and archaeology. These explored issues of data size; quality control, ethics and data security; replication of large datasets; interoperability; and the preservation of diverse types of data; and (c) undertaking a validation and dissemination workshop that sought to better understand how to match policies with stakeholder drivers and motivations to increase their effectiveness in promoting Open Access to research data. The research findings include that there is clearly an overall drive for Open Data Access within the policy documents, which is part of a wider drive for open science in general. This is underpinned by the view of science as an open enterprise. Although there is a strong argument for publicly funded science to be made open to the public the details of how to make research data open as yet still unclear. Our research found

  6. Similar reliability and equivalent performance of female and male mice in the open field and water‐maze place navigation task

    Science.gov (United States)

    Fritz, Ann‐Kristina; Amrein, Irmgard

    2017-01-01

    Although most nervous system diseases affect women and men differentially, most behavioral studies using mouse models do not include subjects of both sexes. Many researchers worry that data of female mice may be unreliable due to the estrous cycle. Here, we retrospectively evaluated sex effects on coefficient of variation (CV) in 5,311 mice which had performed the same place navigation protocol in the water‐maze and in 4,554 mice tested in the same open field arena. Confidence intervals for Cohen's d as measure of effect size were computed and tested for equivalence with 0.2 as equivalence margin. Despite the large sample size, only few behavioral parameters showed a significant sex effect on CV. Confidence intervals of effect size indicated that CV was either equivalent or showed a small sex difference at most, accounting for less than 2% of total group to group variation of CV. While female mice were potentially slightly more variable in water‐maze acquisition and in the open field, males tended to perform less reliably in the water‐maze probe trial. In addition to evaluating variability, we also directly compared mean performance of female and male mice and found them to be equivalent in both water‐maze place navigation and open field exploration. Our data confirm and extend other large scale studies in demonstrating that including female mice in experiments does not cause a relevant increase of data variability. Our results make a strong case for including mice of both sexes whenever open field or water‐maze are used in preclinical research. PMID:28654717

  7. Ballooning modes on open magnetic field lines

    International Nuclear Information System (INIS)

    Hameiri, E.

    1999-01-01

    The ballooning instability on open magnetic field lines is given a thorough mathematical analysis. It is shown that resistive bounding ends (endplates) induce the same stability properties as insulating ends. When unstable, the maximal growth rate increases monotonically with boundary resistivity. An interchange instability may be present, and one necessary condition for its stability is that ∫dl/B be constant on pressure surfaces. (This is an equilibrium existence condition for systems with closed magnetic field lines.) Another necessary condition for interchange stability has the same form as in the closed line case. Precise necessary and sufficient stability criteria are given for various types of bounding ends, including insulating, resistive, and perfectly conducting. copyright 1999 American Institute of Physics

  8. Open Access to Research Articles and Data: Library Roles

    Science.gov (United States)

    Joseph, Heather

    2015-08-01

    Over the past decade, a handful of key developments have caused scholars and researchers to rethink not only the way they conduct their work, but also the way in which they communicate it to others. The advent of the Internet has provided unprecedented opportunities for immediate, cost effective global connectivity, opening up new possibilities for collaboration and communication. This has resulted in scholarship increasingly being conducted in the online environment, and a vast amount of new digital information being generated and made widely available to those interested in using it. Additionally, the Internet is a dynamic environment, with new channels for producing and sharing information in a myriad of formats emerging frequently.In higher education, the momentum of the burgeoning movement towards "open" sharing of information of all kinds continues to gain traction. In particular, advancements in the areas of opening up access to articles and reserch data are increasingly visible. In both of these areas, academic and research libraries are playing important, central roles in promoting the awareness of the potential costs and benefits of a more open research environment, as well as defining new roles for libraries in this digital environment.As this push for grater openness continues, these fronts are intersecting in interesting and potentially transformative ways. The Open Access and Open Data movements share fundamental philosophical commonalities that make collaboration a natural outcome. Both movements place a premium on reducing barriers to discovering and accessing pertinent digital information. Perhaps even more significantly, both explicitly recognize that enabling productive use of digital information is key to unlocking its full value. As a result of these shared priorities, there are a wide variety of common strategies that libraries can take to help advance research, presenting new opportunities for deeper collaboration to take place.This talk will

  9. Open innovation

    DEFF Research Database (Denmark)

    West, Joel; Bogers, Marcel

    2017-01-01

    Interest in open innovation (OI) as a field of research has grown exponentially since the phrase was coined by Chesbrough in his 2003 book, with numerous articles, special issues, books, and conference sessions. Various reviews of the literature have summarized prior work, offered new frameworks......, and identified opportunities for future research. Here we summarize these opportunities, which include more research on outbound OI, the role of open innovation in services, and network forms of collaboration such as consortia, communities, ecosystems, and platforms. Research should also examine the use of OI...... by small, new, and not-for-profit organizations, as well as the linkage of individual actions and motivations to open innovation. Other opportunities include better measuring the costs, benefits, antecedents, mediators and moderators of the effects of OI on performance, and understanding why and how OI...

  10. Open Source and Open Content: a Framework for Global Collaboration in Social-Ecological Research

    Directory of Open Access Journals (Sweden)

    Charles Schweik

    2005-06-01

    Full Text Available This paper discusses opportunities for alternative collaborative approaches for social-ecological research in general and, in this context, for modeling land-use/land-cover change. In this field, the rate of progress in academic research is steady but perhaps not as rapid or efficient as might be possible with alternative organizational frameworks. The convergence of four phenomena provides new opportunities for cross-organizational collaboration: (1 collaborative principles related to "open source" (OS software development, (2 the emerging area of "open content" (OC licensing, (3 the World Wide Web as a platform for scientific communication, and (4 the traditional concept of peer review. Although private individuals, government organizations, and even companies have shown interest in the OS paradigm as an alternative model for software development, it is less commonly recognized that this collaborative framework is a potential innovation of much greater proportions. In fact, it can guide the collective development of any intellectual content, not just software. This paper has two purposes. First, we describe OS and OC licensing, dispense with some myths about OS, and relate these structures to traditional scientific process. Second, we outline how these ideas can be applied in an area of collaborative research relevant to the study of social-ecological systems. It is important to recognize that the concept of OS is not new, but the idea of borrowing OS principles and using OC licensing for broader scientific collaboration is new. Over the last year, we have been trying to initiate such an OS/OC collaboration in the context of modeling land use and land cover. In doing so, we have identified some key issues that need to be considered, including project initiation, incentives of project participants, collaborative infrastructure, institutional design and governance, and project finance. OS/OC licensing is not a universal solution suitable for all

  11. Variation in Depth Dose Data between Open and Wedge Fields for 6 MV X-Rays

    International Nuclear Information System (INIS)

    U, Hong; Ryu, M. S. Samuel; Park, In Kyu

    1989-01-01

    Central axis depth dose data for 6 MV X-rays, including tissue maximum ratios, were measured for wedge fields according to Tatcher equation. In wedge fields, the differences in magnitude which increased with depth, field size, and wedge thickness increased when compared with the corresponding open field data. However, phantom scatter correction factors for wedge fields differed less that 1% from the corresponding open field factors. The differences in central axis percent depth dose between two types of fields indicated beam hardening by the wedge filter. The deviation of percent depth doses and scatter correction factors between the effective wedge field and the nominal wedge field at same angle was negligible. The differences were less than 3.26% between the nominal or effective wedge fields and the open fields for percent depth doses to the depth 7cm in 6cm x 6cm field. For larger (10cm x 10cm) field size, however, the deviation of percent depth doses between the nominal or effective wedge fields and the open fields were greater-dosimetric errors were 3.56% at depth 7cm and nearly 5.30% at 12cm. We suggest that the percent depth doses of individual wedge and wedge transmission factors should be considered for the dose calculation or monitor setting in the treatment of deep seated tumor

  12. Real analytic solutions for marginal deformations in open superstring field theory

    International Nuclear Information System (INIS)

    Okawa, Yuji

    2007-01-01

    We construct analytic solutions for marginal deformations satisfying the reality condition in open superstring field theory formulated by Berkovits when operator products made of the marginal operator and the associated superconformal primary field are regular. Our strategy is based on the recent observation by Erler that the problem of finding solutions for marginal deformations in open superstring field theory can be reduced to a problem in the bosonic theory of finding a finite gauge parameter for a certain pure-gauge configuration labeled by the parameter of the marginal deformation. We find a gauge transformation generated by a real gauge parameter which infinitesimally changes the deformation parameter and construct a finite gauge parameter by its path-ordered exponential. The resulting solution satisfies the reality condition by construction

  13. Real analytic solutions for marginal deformations in open superstring field theory

    International Nuclear Information System (INIS)

    Okawa, Y.

    2007-04-01

    We construct analytic solutions for marginal deformations satisfying the reality condition in open superstring field theory formulated by Berkovits when operator products made of the marginal operator and the associated superconformal primary field are regular. Our strategy is based on the recent observation by Erler that the problem of finding solutions for marginal deformations in open superstring field theory can be reduced to a problem in the bosonic theory of finding a finite gauge parameter for a certain pure-gauge configuration labeled by the parameter of the marginal deformation. We find a gauge transformation generated by a real gauge parameter which infinitesimally changes the deformation parameter and construct a finite gauge parameter by its path-ordered exponential. The resulting solution satisfies the reality condition by construction. (orig.)

  14. Open Admissions: A Bibliography for Research and Application.

    Science.gov (United States)

    Shrier, Irene; Lavin, David E.

    This bibliography presents materials for research and application of open admissions policies in higher education. Sections cover: open admissions; factors influencing high school graduates to attend college; disadvantaged and minority students; precollege and special programs; English and reading skills; general compensatory programs; dropouts;…

  15. OpenSHS: Open Smart Home Simulator

    Directory of Open Access Journals (Sweden)

    Nasser Alshammari

    2017-05-01

    Full Text Available This paper develops a new hybrid, open-source, cross-platform 3D smart home simulator, OpenSHS, for dataset generation. OpenSHS offers an opportunity for researchers in the field of the Internet of Things (IoT and machine learning to test and evaluate their models. Following a hybrid approach, OpenSHS combines advantages from both interactive and model-based approaches. This approach reduces the time and efforts required to generate simulated smart home datasets. We have designed a replication algorithm for extending and expanding a dataset. A small sample dataset produced, by OpenSHS, can be extended without affecting the logical order of the events. The replication provides a solution for generating large representative smart home datasets. We have built an extensible library of smart devices that facilitates the simulation of current and future smart home environments. Our tool divides the dataset generation process into three distinct phases: first design: the researcher designs the initial virtual environment by building the home, importing smart devices and creating contexts; second, simulation: the participant simulates his/her context-specific events; and third, aggregation: the researcher applies the replication algorithm to generate the final dataset. We conducted a study to assess the ease of use of our tool on the System Usability Scale (SUS.

  16. OpenSHS: Open Smart Home Simulator.

    Science.gov (United States)

    Alshammari, Nasser; Alshammari, Talal; Sedky, Mohamed; Champion, Justin; Bauer, Carolin

    2017-05-02

    This paper develops a new hybrid, open-source, cross-platform 3D smart home simulator, OpenSHS, for dataset generation. OpenSHS offers an opportunity for researchers in the field of the Internet of Things (IoT) and machine learning to test and evaluate their models. Following a hybrid approach, OpenSHS combines advantages from both interactive and model-based approaches. This approach reduces the time and efforts required to generate simulated smart home datasets. We have designed a replication algorithm for extending and expanding a dataset. A small sample dataset produced, by OpenSHS, can be extended without affecting the logical order of the events. The replication provides a solution for generating large representative smart home datasets. We have built an extensible library of smart devices that facilitates the simulation of current and future smart home environments. Our tool divides the dataset generation process into three distinct phases: first design: the researcher designs the initial virtual environment by building the home, importing smart devices and creating contexts; second, simulation: the participant simulates his/her context-specific events; and third, aggregation: the researcher applies the replication algorithm to generate the final dataset. We conducted a study to assess the ease of use of our tool on the System Usability Scale (SUS).

  17. Correlation between two parameters of mice behaviour in the open field test

    OpenAIRE

    Stojanović, Nikola M.; Ranđelović, Pavle J.; Radulović, Niko S.

    2017-01-01

    The open field test is being used extensively for the determination of different aspects of animal behaviour for over seventy years. The correlation between different behavioural parameters obtained in this test, although previously studied, is still debatable. Thus, we aimed to analyze and correlate behaviour scores to estimate the importance of individual parameters in this type of experiment. The open field test was performed on male BALB/c mice treated with either saline (10 ml/kg) or dia...

  18. A hybrid analytical model for open-circuit field calculation of multilayer interior permanent magnet machines

    Science.gov (United States)

    Zhang, Zhen; Xia, Changliang; Yan, Yan; Geng, Qiang; Shi, Tingna

    2017-08-01

    Due to the complicated rotor structure and nonlinear saturation of rotor bridges, it is difficult to build a fast and accurate analytical field calculation model for multilayer interior permanent magnet (IPM) machines. In this paper, a hybrid analytical model suitable for the open-circuit field calculation of multilayer IPM machines is proposed by coupling the magnetic equivalent circuit (MEC) method and the subdomain technique. In the proposed analytical model, the rotor magnetic field is calculated by the MEC method based on the Kirchhoff's law, while the field in the stator slot, slot opening and air-gap is calculated by subdomain technique based on the Maxwell's equation. To solve the whole field distribution of the multilayer IPM machines, the coupled boundary conditions on the rotor surface are deduced for the coupling of the rotor MEC and the analytical field distribution of the stator slot, slot opening and air-gap. The hybrid analytical model can be used to calculate the open-circuit air-gap field distribution, back electromotive force (EMF) and cogging torque of multilayer IPM machines. Compared with finite element analysis (FEA), it has the advantages of faster modeling, less computation source occupying and shorter time consuming, and meanwhile achieves the approximate accuracy. The analytical model is helpful and applicable for the open-circuit field calculation of multilayer IPM machines with any size and pole/slot number combination.

  19. Can open-source R&D reinvigorate drug research?

    Science.gov (United States)

    Munos, Bernard

    2006-09-01

    The low number of novel therapeutics approved by the US FDA in recent years continues to cause great concern about productivity and declining innovation. Can open-source drug research and development, using principles pioneered by the highly successful open-source software movement, help revive the industry?

  20. Open Wilson lines and generalized star product in noncommutative scalar field theories

    International Nuclear Information System (INIS)

    Kiem, Youngjai; Sato, Haru-Tada; Rey, Soo-Jong; Yee, Jung-Tay

    2002-01-01

    Open Wilson line operators and a generalized star product have been studied extensively in noncommutative gauge theories. We show that they also show up in noncommutative scalar field theories as universal structures. We first point out that the dipole picture of noncommutative geometry provides an intuitive argument for the robustness of the open Wilson lines and generalized star products therein. We calculate the one-loop effective action of noncommutative scalar field theory with a cubic self-interaction and show explicitly that the generalized star products arise in the nonplanar part. It is shown that, at the low-energy, large noncommutativity limit, the nonplanar part is expressible solely in terms of the scalar open Wilson line operator and descendants

  1. OpenFOAM: Open source CFD in research and industry

    Science.gov (United States)

    Jasak, Hrvoje

    2009-12-01

    The current focus of development in industrial Computational Fluid Dynamics (CFD) is integration of CFD into Computer-Aided product development, geometrical optimisation, robust design and similar. On the other hand, in CFD research aims to extend the boundaries ofpractical engineering use in "non-traditional " areas. Requirements of computational flexibility and code integration are contradictory: a change of coding paradigm, with object orientation, library components, equation mimicking is proposed as a way forward. This paper describes OpenFOAM, a C++ object oriented library for Computational Continuum Mechanics (CCM) developed by the author. Efficient and flexible implementation of complex physical models is achieved by mimicking the form ofpartial differential equation in software, with code functionality provided in library form. Open Source deployment and development model allows the user to achieve desired versatility in physical modeling without the sacrifice of complex geometry support and execution efficiency.

  2. The open research system: a web-based metadata and data repository for collaborative research

    Science.gov (United States)

    Charles M. Schweik; Alexander Stepanov; J. Morgan Grove

    2005-01-01

    Beginning in 1999, a web-based metadata and data repository we call the "open research system" (ORS) was designed and built to assist geographically distributed scientific research teams. The purpose of this innovation was to promote the open sharing of data within and across organizational lines and across geographic distances. As the use of the system...

  3. Analysis on temperature field and flow field of reactor core barrel openings for China experiment fast reactor

    International Nuclear Information System (INIS)

    Zhang Yabo; Yang Hongyi

    2008-01-01

    The paper gives analysis of the temperature and flow field around openings by software CFX, and figures out the flow direction around openings under CEFR normal condition. The calculation result is consistent with the test result of CAPX (the test-bed of decay heat removal system) and ground for the safety analysis later. (authors)

  4. Similar reliability and equivalent performance of female and male mice in the open field and water-maze place navigation task.

    Science.gov (United States)

    Fritz, Ann-Kristina; Amrein, Irmgard; Wolfer, David P

    2017-09-01

    Although most nervous system diseases affect women and men differentially, most behavioral studies using mouse models do not include subjects of both sexes. Many researchers worry that data of female mice may be unreliable due to the estrous cycle. Here, we retrospectively evaluated sex effects on coefficient of variation (CV) in 5,311 mice which had performed the same place navigation protocol in the water-maze and in 4,554 mice tested in the same open field arena. Confidence intervals for Cohen's d as measure of effect size were computed and tested for equivalence with 0.2 as equivalence margin. Despite the large sample size, only few behavioral parameters showed a significant sex effect on CV. Confidence intervals of effect size indicated that CV was either equivalent or showed a small sex difference at most, accounting for less than 2% of total group to group variation of CV. While female mice were potentially slightly more variable in water-maze acquisition and in the open field, males tended to perform less reliably in the water-maze probe trial. In addition to evaluating variability, we also directly compared mean performance of female and male mice and found them to be equivalent in both water-maze place navigation and open field exploration. Our data confirm and extend other large scale studies in demonstrating that including female mice in experiments does not cause a relevant increase of data variability. Our results make a strong case for including mice of both sexes whenever open field or water-maze are used in preclinical research. © 2017 The Authors. American Journal of Medical Genetics Part C Published by Wiley Periodicals, Inc.

  5. Research on the flow field of undershot cross-flow water turbines using experiments and numerical analysis

    International Nuclear Information System (INIS)

    Nishi, Y; Inagaki, T; Li, Y; Omiya, R; Hatano, K

    2014-01-01

    The purpose of this research is to develop a water turbine appropriate for low-head open channels in order to effectively utilize the unused hydropower energy of rivers and agricultural waterways. The application of the cross-flow runner to open channels as an undershot water turbine has come under consideration and, to this end, a significant simplification was attained by removing the casings. However, the flow field of undershot cross-flow water turbines possesses free surfaces. This means that with the variation in the rotational speed, the water depth around the runner will change and flow field itself is significantly altered. Thus it is necessary to clearly understand the flow fields with free surfaces in order to improve the performance of this turbine. In this research, the performance of this turbine and the flow field were studied through experiments and numerical analysis. The experimental results on the performance of this turbine and the flow field were consistent with the numerical analysis. In addition, the inlet and outlet regions at the first and second stages of this water turbine were clarified

  6. Predicting Canopy Temperatures without and with Infrared Heating of Open-Field Plots and Energy Requirements for such Infrared Heating

    Science.gov (United States)

    In order to determine the likely effect of global warming on agricultural productivity while avoiding experimental artifacts, there is a need to conduct warming research under conditions as representative as possible of future open fields, i.e., temperature free-air controlled enhancement (T-FACE) e...

  7. State of the art report on open access publishing of research data in the humanities : D7.1. HaS DARIAH

    NARCIS (Netherlands)

    Buddenbohm, Stefan; Cretin, Nathanael; Dijk, E.M.S.; Gaiffe, Bertrand; De Jong, M.A.; Le Tellier-Becquart, Nathalie; Minel, Jean-Luc

    2016-01-01

    Publishing research data as open data is not yet common practice for researchers in the arts and humanities, and lags behind other scientific fields, such as the natural sciences. Moreover, even when humanities researchers publish their data in repositories and archives, these data are often hard to

  8. University and Research Libraries in Europe Working towards Open Access

    Directory of Open Access Journals (Sweden)

    Paul Ayris

    2011-02-01

    Full Text Available This paper presents an overview of ways in which LIBER (Association of European Research Libraries and its members are working towards embedding Open Access approaches to the dissemination of research outputs. It does this in three ways — by looking at current debates in which LIBER has become interested, on the economics of Open Access; by highlighting new projects in which LIBER is engaged, to develop new models and services via Open Access; and by looking at a model of best practice amongst LIBER members for developing an institutional Open Access mandate. The paper ends by drawing conclusions about the vitality of the work of LIBER member libraries in the Open Access landscape.

  9. The integration of open access journals in the scholarly communication system: Three science fields

    DEFF Research Database (Denmark)

    Faber Frandsen, Tove

    2009-01-01

    across disciplines. This study is an analysis of the citing behaviour in journals within three science fields: biology, mathematics, and pharmacy and pharmacology. It is a statistical analysis of OAJs as well as non-OAJs including both the citing and cited side of the journal to journal citations......The greatest number of open access journals (OAJs) is found in the sciences and their influence is growing. However, there are only a few studies on the acceptance and thereby integration of these OAJs in the scholarly communication system. Even fewer studies provide insight into the differences....... The multivariate linear regression reveals many similarities in citing behaviour across fields and media. But it also points to great differences in the integration of OAJs. The integration of OAJs in the scholarly communication system varies considerably across fields. The implications for bibliometric research...

  10. IT-Enabled Knowledge Creation for Open Innovation

    NARCIS (Netherlands)

    Eseryel, U. Yeliz

    2014-01-01

    Open innovation is increasingly important for researchers and practitioners alike. Open innovation is closely linked to knowledge creation in that, with open innovation, knowledge inflows and outflows are exploited for innovation. In the information systems field, open innovation has been closely

  11. OpenFOAM: Open source CFD in research and industry

    Directory of Open Access Journals (Sweden)

    Hrvoje Jasak

    2009-12-01

    Full Text Available The current focus of development in industrial Computational Fluid Dynamics (CFD is integration of CFD into Computer-Aided product development, geometrical optimisation, robust design and similar. On the other hand, in CFD research aims to extend the boundaries of practical engineering use in “non-traditional” areas. Requirements of computational flexibility and code integration are contradictory: a change of coding paradigm, with object orientation, library components, equation mimicking is proposed as a way forward. This paper describes OpenFOAM, a C++ object oriented library for Computational Continuum Mechanics (CCM developed by the author. Efficient and flexible implementation of complex physical models is achieved by mimicking the form of partial differential equation in software, with code functionality provided in library form. Open Source deployment and development model allows the user to achieve desired versatility in physical modeling without the sacrifice of complex geometry support and execution efficiency.

  12. Open-ended magnetic confinement systems for fusion

    International Nuclear Information System (INIS)

    Post, R.F.; Ryutov, D.D.

    1995-05-01

    Magnetic confinement systems that use externally generated magnetic fields can be divided topologically into two classes: ''closed'' and 'open''. The tokamak, the stellarator, and the reversed-field-pinch approaches are representatives of the first category, while mirror-based systems and their variants are of the second category. While the recent thrust of magnetic fusion research, with its emphasis on the tokamak, has been concentrated on closed geometry, there are significant reasons for the continued pursuit of research into open-ended systems. The paper discusses these reasons, reviews the history and the present status of open-ended systems, and suggests some future directions for the research

  13. Enriched open field facilitates exercise and social interaction in 2 strains of guinea pigs (Cavia porcellus).

    Science.gov (United States)

    Brewer, Jacob S; Bellinger, Seanceray A; Joshi, Prianca; Kleven, Gale A

    2014-07-01

    Current housing guidelines for laboratory rodents include recommendations for enrichment. Working with guinea pigs, we have developed an open-field enrichment paradigm that provides several aspects of this species' natural environment. These naturalistic aspects include access to increased space for exploration, access to western timothy (Phleum pratense L.) hay, and grouping as a herd to facilitate social interaction. To determine the immediate effect on behavior from access to the enriched environment, female guinea pigs from 2 strains, IAF Hairless and NIH Hartley, were observed in both standard home cages and an open-field enriched environment. Subjects were housed with cagemates in pairs for the home-cage observation and were grouped as a herd when in the open-field arena. Behaviors were videorecorded for 1 h and then scored. Salivary cortisol levels were measured both prior to and immediately after behavioral observations. Analyses revealed higher levels of activity and social interaction in the open-field arena compared with the home cage, with no significant change in salivary cortisol levels. These results suggest that exposure to the open-field environment provide increased opportunities for exercise and social enrichment. Although additional studies are needed to determine long-term effects on experimental outcomes, the open-field configuration holds promise as a laboratory enrichment paradigm for guinea pigs.

  14. On open and closed field line regions in Tsyganenko's field model and their possible associations with horse collar auroras

    Science.gov (United States)

    Birn, J.; Hones, E. W., Jr.; Craven, J. D.; Frank, L. A.; Elphinstone, R. D.; Stern, D. P.

    1991-01-01

    The boundary between open and closed field lines is investigated in the empirical Tsyganenko (1987) magnetic field model. All field lines extending to distances beyond -70 R(E), the tailward velocity limit of the Tsyganenko model are defined as open, while all other field lines, which cross the equatorial plane earthward of -70 R(E) and are connected with the earth at both ends, are assumed closed. It is found that this boundary at the surface of the earth, identified as the polar cap boundary, can exhibit the arrowhead shape, pointed toward the sun, which is found in horse collar auroras. For increasing activity levels, the polar cap increases in area and becomes rounder, so that the arrowhead shape is less pronounced. The presence of a net B(y) component can also lead to considerable rounding of the open flux region. The arrowhead shape is found to be closely associated with the increase of B(z) from the midnight region to the flanks of the tail, consistent with a similar increase of the plasma sheet thickness.

  15. Clinical effects of buprenorphine on open field behaviour and gait symmetry in healthy and lame weaned piglets.

    Science.gov (United States)

    Meijer, Ellen; van Nes, Arie; Back, Willem; van der Staay, Franz Josef

    2015-12-01

    Lameness in pigs decreases animal welfare and economic profit for the farmer. An important reason for impaired welfare in lame animals is pain due to lameness. No direct measurement of pain is possible in animals, and methods to indirectly detect and quantify the amount of pain an animal is experiencing are urgently needed. In this study, two methods to assess pain associated with lameness in pigs were evaluated to determine if they were sensitive enough to detect a lameness reduction as an effect of an experimental analgesic medication. Asymmetry associated with lameness was objectively quantified using pressure mat kinetic parameters: peak vertical force (PVF), load rate (LR), vertical impulse (VI) and peak vertical pressure (PVP). Locomotor activity was assessed in an open field test. A dose of 0.04 mg/kg buprenorphine, a strong analgesic, was used to treat 10 lame pigs, while eight other lame pigs, treated with physiological saline solution, served as controls. Buprenorphine decreased lameness-associated asymmetry for pressure mat LR (P = 0.002), VI (P = 0.003) and PVP (P = 0.001) and increased activity of the lame pigs in the open field (P = 0.023), while saline-treated animals did not show any changes in asymmetry and became less active in the open field (P open field test are both sensitive enough to detect the analgesic effects of buprenorphine when used to treat moderate to severe clinical pain in a relatively small group of affected pigs. The methods used in this study may also provide promising additional tools for future research into early pain recognition and lameness treatment in pigs. Copyright © 2015 Elsevier Ltd. All rights reserved.

  16. Openness versus Secrecy in Scientific Research Abstract.

    Science.gov (United States)

    Resnik, David B

    2006-02-01

    Openness is one of the most important principles in scientific inquiry, but there are many good reasons for maintaining secrecy in research, ranging from the desire to protect priority, credit, and intellectual property, to the need to safeguard the privacy of research participants or minimize threats to national or international security. This article examines the clash between openness and secrecy in science in light of some recent developments in information technology, business, and politics, and makes some practical suggestions for resolving conflicts between openness and secrecy."By academic freedom I understand the right to search for the truth and to publish and teach what one holds to be true. This right also implies a duty; one must not conceal any part of what one has recognized to be true. It is evident that any restriction of academic freedom serves to restrain the dissemination of knowledge, thereby impeding rational judgment and action."Albert Einstein, quotation inscribed on his statute in front of the National Academy of Sciences, Washington, DC.

  17. Magnetar giant flares in multipolar magnetic fields. I. Fully and partially open eruptions of flux ropes

    International Nuclear Information System (INIS)

    Huang, Lei; Yu, Cong

    2014-01-01

    We propose a catastrophic eruption model for the enormous energy release of magnetars during giant flares, in which a toroidal and helically twisted flux rope is embedded within a force-free magnetosphere. The flux rope stays in stable equilibrium states initially and evolves quasi-statically. Upon the loss of equilibrium, the flux rope cannot sustain the stable equilibrium states and erupts catastrophically. During the process, the magnetic energy stored in the magnetosphere is rapidly released as the result of destabilization of global magnetic topology. The magnetospheric energy that could be accumulated is of vital importance for the outbursts of magnetars. We carefully establish the fully open fields and partially open fields for various boundary conditions at the magnetar surface and study the relevant energy thresholds. By investigating the magnetic energy accumulated at the critical catastrophic point, we find that it is possible to drive fully open eruptions for dipole-dominated background fields. Nevertheless, it is hard to generate fully open magnetic eruptions for multipolar background fields. Given the observational importance of the multipolar magnetic fields in the vicinity of the magnetar surface, it would be worthwhile to explore the possibility of the alternative eruption approach in multipolar background fields. Fortunately, we find that flux ropes may give rise to partially open eruptions in the multipolar fields, which involve only partial opening of background fields. The energy release fractions are greater for cases with central-arcaded multipoles than those with central-caved multipoles that emerged in background fields. Eruptions would fail only when the centrally caved multipoles become extremely strong.

  18. Research on OpenStack of open source cloud computing in colleges and universities’ computer room

    Science.gov (United States)

    Wang, Lei; Zhang, Dandan

    2017-06-01

    In recent years, the cloud computing technology has a rapid development, especially open source cloud computing. Open source cloud computing has attracted a large number of user groups by the advantages of open source and low cost, have now become a large-scale promotion and application. In this paper, firstly we briefly introduced the main functions and architecture of the open source cloud computing OpenStack tools, and then discussed deeply the core problems of computer labs in colleges and universities. Combining with this research, it is not that the specific application and deployment of university computer rooms with OpenStack tool. The experimental results show that the application of OpenStack tool can efficiently and conveniently deploy cloud of university computer room, and its performance is stable and the functional value is good.

  19. Remarks on the relation between different (open) string field theories

    International Nuclear Information System (INIS)

    De Alwis, S.P.

    1987-01-01

    It is shown that the different three-string vertices, related by conformal transformations, are in the same BRST cohomology class. We use this result to discuss the relation between different (open) string field theories. (orig.)

  20. Jet outflow and open field line measurements on the C-2U advanced beam-driven field-reversed configuration plasma experiment.

    Science.gov (United States)

    Sheftman, D; Gupta, D; Roche, T; Thompson, M C; Giammanco, F; Conti, F; Marsili, P; Moreno, C D

    2016-11-01

    Knowledge and control of the axial outflow of plasma particles and energy along open-magnetic-field lines are of crucial importance to the stability and longevity of the advanced beam-driven field-reversed configuration plasma. An overview of the diagnostic methods used to perform measurements on the open field line plasma on C-2U is presented, including passive Doppler impurity spectroscopy, microwave interferometry, and triple Langmuir probe measurements. Results of these measurements provide the jet ion temperature and axial velocity, electron density, and high frequency density fluctuations.

  1. On the electric field model for an open magnetosphere

    Science.gov (United States)

    Wang, Zhi; Ashour-Abdalla, Maha; Walker, Raymond J.

    1993-01-01

    We have developed a new canonical separator line type magnetospheric magnetic field and electric field model for use in magnetospheric calculations, we determine the magnetic and electric field by controlling the reconnection rate at the subsolar magnetopause. The model is applicable only for purely southward interplanetary magnetic field (IMF). We have obtained a more realistic magnetotail configuration by applying a stretch transformation to an axially symmetric field solution. We also discuss the Stern singularity in which there is an electric field singlarity in the canonical separate line models for B(sub y) not = to 0 by using a new technique that solves for the electric field along a field line directly instead of determining it by a potential mapping. The singularity not only causes an infinite electric field on the polar cap, but also causes the boundary conditions at plus infinity and minus infinity in the solar wind to contradict each other. This means that the canonical separator line models do not represent the open magnetosphere well, except for the case of purely southward IMF.

  2. A hybrid analytical model for open-circuit field calculation of multilayer interior permanent magnet machines

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Zhen [School of Electrical Engineering and Automation, Tianjin University, Tianjin 300072 (China); Xia, Changliang [School of Electrical Engineering and Automation, Tianjin University, Tianjin 300072 (China); Tianjin Engineering Center of Electric Machine System Design and Control, Tianjin 300387 (China); Yan, Yan, E-mail: yanyan@tju.edu.cn [School of Electrical Engineering and Automation, Tianjin University, Tianjin 300072 (China); Geng, Qiang [Tianjin Engineering Center of Electric Machine System Design and Control, Tianjin 300387 (China); Shi, Tingna [School of Electrical Engineering and Automation, Tianjin University, Tianjin 300072 (China)

    2017-08-01

    Highlights: • A hybrid analytical model is developed for field calculation of multilayer IPM machines. • The rotor magnetic field is calculated by the magnetic equivalent circuit method. • The field in the stator and air-gap is calculated by subdomain technique. • The magnetic scalar potential on rotor surface is modeled as trapezoidal distribution. - Abstract: Due to the complicated rotor structure and nonlinear saturation of rotor bridges, it is difficult to build a fast and accurate analytical field calculation model for multilayer interior permanent magnet (IPM) machines. In this paper, a hybrid analytical model suitable for the open-circuit field calculation of multilayer IPM machines is proposed by coupling the magnetic equivalent circuit (MEC) method and the subdomain technique. In the proposed analytical model, the rotor magnetic field is calculated by the MEC method based on the Kirchhoff’s law, while the field in the stator slot, slot opening and air-gap is calculated by subdomain technique based on the Maxwell’s equation. To solve the whole field distribution of the multilayer IPM machines, the coupled boundary conditions on the rotor surface are deduced for the coupling of the rotor MEC and the analytical field distribution of the stator slot, slot opening and air-gap. The hybrid analytical model can be used to calculate the open-circuit air-gap field distribution, back electromotive force (EMF) and cogging torque of multilayer IPM machines. Compared with finite element analysis (FEA), it has the advantages of faster modeling, less computation source occupying and shorter time consuming, and meanwhile achieves the approximate accuracy. The analytical model is helpful and applicable for the open-circuit field calculation of multilayer IPM machines with any size and pole/slot number combination.

  3. Localization of effective actions in open superstring field theory

    Science.gov (United States)

    Maccaferri, Carlo; Merlano, Alberto

    2018-03-01

    We consider the construction of the algebraic part of D-branes tree-level effective action from Berkovits open superstring field theory. Applying this construction to the quartic potential of massless fields carrying a specific worldsheet charge, we show that the full contribution to the potential localizes at the boundary of moduli space, reducing to elementary two-point functions. As examples of this general mechanism, we show how the Yang-Mills quartic potential and the instanton effective action of a Dp/D( p - 4) system are reproduced.

  4. Monitoring of piglets' open field activity and choice behaviour during the replay of maternal vocalization: a comparison between Observer and PID technique.

    Science.gov (United States)

    Puppe, B; Schön, P C; Wendland, K

    1999-07-01

    The paper presents a new system for the automatic monitoring of open field activity and choice behaviour of medium-sized animals. Passive infrared motion detectors (PID) were linked on-line via a digital I/O interface to a personal computer provided with self-developed analysis software based on LabVIEW (PID technique). The set up was used for testing 18 one-week-old piglets (Sus scrofa) for their approach to their mother's nursing vocalization replayed through loudspeakers. The results were validated by comparison with a conventional Observer technique, a computer-aided direct observation. In most of the cases, no differences were seen between the Observer and PID technique regarding the percentage of stay in previously defined open field segments, the locomotor open field activity, and the choice behaviour. The results revealed that piglets are clearly attracted by their mother's nursing vocalization. The monitoring system presented in this study is thus suitable for detailed behavioural investigations of individual acoustic recognition. In general, the PID technique is a useful tool for research into the behaviour of individual animals in a restricted open field which does not rely on subjective analysis by a human observer.

  5. Open field locomotor activity and anxiety-related behaviors in mucopolysaccharidosis type IIIA mice.

    Science.gov (United States)

    Lau, Adeline A; Crawley, Allison C; Hopwood, John J; Hemsley, Kim M

    2008-08-05

    Mucopolysaccharidosis (MPS) IIIA, or Sanfilippo syndrome, is a lysosomal storage disorder characterized by severe and progressive neuropathology. Following an asymptomatic period, patients may present with sleep disturbances, cognitive decline, aggressive tendencies and hyperactivity. A naturally-occurring mouse model of MPS IIIA also exhibits many of these behavioral features and has been recently back-crossed onto a C57BL/6 genetic background. To more thoroughly characterize the behavioral phenotype of congenic MPS IIIA mice, we assessed exploratory activity and unconditioned anxiety-related behavior in the elevated plus maze (EPM) and open field locomotor activity. Although MPS IIIA male mice were less active in the EPM at 18 and 20 weeks of age, they were more likely to explore the open arms than their normal counter-parts suggesting reduced anxiety. Repeated EPM testing reduced exploration of the open arms in MPS IIIA mice. In the open field test, significant reductions in activity were evident in naïve-tested male MPS IIIA mice from 10 weeks of age. Female normal and MPS IIIA mice displayed similar exploratory activity in the open field test. These differences in anxiety and locomotor activity will allow us to evaluate the efficacy of therapeutic regimes for MPS IIIA as a forerunner to developing safe and effective therapies for Sanfilippo patients.

  6. Accelerating Translational Research through Open Science: The Neuro Experiment.

    Science.gov (United States)

    Gold, E Richard

    2016-12-01

    Translational research is often afflicted by a fundamental problem: a limited understanding of disease mechanisms prevents effective targeting of new treatments. Seeking to accelerate research advances and reimagine its role in the community, the Montreal Neurological Institute (Neuro) announced in the spring of 2016 that it is launching a five-year experiment during which it will adopt Open Science-open data, open materials, and no patenting-across the institution. The experiment seeks to examine two hypotheses. The first is whether the Neuro's Open Science initiative will attract new private partners. The second hypothesis is that the Neuro's institution-based approach will draw companies to the Montreal region, where the Neuro is based, leading to the creation of a local knowledge hub. This article explores why these hypotheses are likely to be true and describes the Neuro's approach to exploring them.

  7. Accelerating Translational Research through Open Science: The Neuro Experiment.

    Directory of Open Access Journals (Sweden)

    E Richard Gold

    2016-12-01

    Full Text Available Translational research is often afflicted by a fundamental problem: a limited understanding of disease mechanisms prevents effective targeting of new treatments. Seeking to accelerate research advances and reimagine its role in the community, the Montreal Neurological Institute (Neuro announced in the spring of 2016 that it is launching a five-year experiment during which it will adopt Open Science-open data, open materials, and no patenting-across the institution. The experiment seeks to examine two hypotheses. The first is whether the Neuro's Open Science initiative will attract new private partners. The second hypothesis is that the Neuro's institution-based approach will draw companies to the Montreal region, where the Neuro is based, leading to the creation of a local knowledge hub. This article explores why these hypotheses are likely to be true and describes the Neuro's approach to exploring them.

  8. Use of the Open Field Maze to measure locomotor and anxiety-like behavior in mice.

    Science.gov (United States)

    Seibenhener, Michael L; Wooten, Michael C

    2015-02-06

    Animal models have proven to be invaluable to researchers trying to answer questions regarding the mechanisms of behavior. The Open Field Maze is one of the most commonly used platforms to measure behaviors in animal models. It is a fast and relatively easy test that provides a variety of behavioral information ranging from general ambulatory ability to data regarding the emotionality of the subject animal. As it relates to rodent models, the procedure allows the study of different strains of mice or rats both laboratory bred and wild-captured. The technique also readily lends itself to the investigation of different pharmacological compounds for anxiolytic or anxiogenic effects. Here, a protocol for use of the open field maze to describe mouse behaviors is detailed and a simple analysis of general locomotor ability and anxiety-related emotional behaviors between two strains of C57BL/6 mice is performed. Briefly, using the described protocol we show Wild Type mice exhibited significantly less anxiety related behaviors than did age-matched Knock Out mice while both strains exhibited similar ambulatory ability.

  9. An open science cloud for scientific research

    Science.gov (United States)

    Jones, Bob

    2016-04-01

    The Helix Nebula initiative was presented at EGU 2013 (http://meetingorganizer.copernicus.org/EGU2013/EGU2013-1510-2.pdf) and has continued to expand with more research organisations, providers and services. The hybrid cloud model deployed by Helix Nebula has grown to become a viable approach for provisioning ICT services for research communities from both public and commercial service providers (http://dx.doi.org/10.5281/zenodo.16001). The relevance of this approach for all those communities facing societal challenges in explained in a recent EIROforum publication (http://dx.doi.org/10.5281/zenodo.34264). This presentation will describe how this model brings together a range of stakeholders to implement a common platform for data intensive services that builds upon existing public funded e-infrastructures and commercial cloud services to promote open science. It explores the essential characteristics of a European Open Science Cloud if it is to address the big data needs of the latest generation of Research Infrastructures. The high-level architecture and key services as well as the role of standards is described. A governance and financial model together with the roles of the stakeholders, including commercial service providers and downstream business sectors, that will ensure a European Open Science Cloud can innovate, grow and be sustained beyond the current project cycles is described.

  10. Developing a low-cost open-source CTD for research and outreach

    Science.gov (United States)

    Thaler, A. D.; Sturdivant, K.

    2013-12-01

    Developing a low-cost open-source CTD for research and outreach Andrew David Thaler and Kersey Sturdivant Conductivity, temperature, and depth (CTD). With these three measurements, marine scientists can unlock ocean patterns hidden beneath the waves. The ocean is not uniform, it its filled with swirling eddies, temperature boundaries, layers of high and low salinity, changing densities, and many other physical characteristics. To reveal these patterns, oceanographers use a tool called the CTD. A CTD is found on almost every major research vessel. Rare is the scientific expedition-whether it be coastal work in shallow estuaries or journeys to the deepest ocean trenches-that doesn't begin with the humble CTD cast. The CTD is not cheap. Commercial CTD's start at more the 5,000 and can climb as high as 25,000 or more. We believe that the prohibitive cost of a CTD is an unacceptable barrier to open science. The price tag excludes individuals and groups who lack research grants or significant private funds from conducting oceanographic research. We want to make this tool-the workhorse of oceanographic research-available to anyone with an interest in the oceans. The OpenCTD is a low-cost, open-source CTD suitable for both educators and scientists. The platform is built using readily available parts and is powered by an Arduino-based microcontroller. Our goal is to create a device that is accurate enough to be used for scientific research and can be constructed for less than $200. Source codes, circuit diagrams, and building plans will be freely available. The final instrument will be effective to 200 meters depth. Why 200 meters? For many coastal regions, 200 meters of water depth covers the majority of the ocean that is accessible by small boat. The OpenCTD is targeted to people working in this niche, where entire research projects can be conducted for less than the cost of a commercial CTD. However, the Open CTD is scalable, and anyone with the inclination can adapt our

  11. Researchers' perspectives on open access scholarly communication in Tanzanian public universities

    Directory of Open Access Journals (Sweden)

    F.W. Dulle

    2009-04-01

    Full Text Available This research explored the awareness, usage and perspectives of Tanzanian researchers on open access as a mode of scholarly communication. A survey questionnaire targeted 544 respondents selected through stratified random sampling from a population of 1088 university researchers of the six public universities in Tanzania. With a response rate of 73%, the data were analysed using the Statistical Package for Social Sciences. The study reveals that the majority of the researchers were aware of and were positive towards open access. Findings further indicate that the majority of researchers in Tanzanian public universities used open access outlets more to access scholarly content than to disseminate their own research findings. It seems that most of these researchers would support open access publishing more if issues of recognition, quality and ownership were resolved. Thus many of them supported the idea of establishing institutional repositories at their respective universities as a way of improving the dissemination of local content. The study recommends that public universities and other research institutions in the country should consider establishing institutional repositories, with appropriate quality assurance measures, to improve the dissemination of research output emanating from these institutions.

  12. UNESCO Launches Open Access Curriculum for Young and Early Career Researchers

    OpenAIRE

    Das, Anup-Kumar

    2015-01-01

    This article narrates the background of UNESCO Curriculum titled "Open Access for Researchers" which was launched on 16th March 2015. This Open Access Curriculum contains five modules for capacity building, awareness raising and sensitizing young and early career researchers affiliated to research laboratories or higher educational institutions across the world.

  13. Standardized UXO Technology Demonstration Site, Open Field Scoring Record Number 426

    National Research Council Canada - National Science Library

    Overbay, Larry, Jr; Boutin, Matthew; Archiable, Robert; Fling, Rick; McClung, Christina; Robitaille, George

    2005-01-01

    ...) utilizing the YPG Standardized UXO Technology Demonstration Site Open Field. Scoring Records have been coordinated by Larry Overbay and the Standardized UXO Technology Demonstration Site Scoring Committee...

  14. Standardized UXO Technology Demonstration Site, Open Field Scoring Record Number 657

    National Research Council Canada - National Science Library

    Overbay, Larry; Robitaille, George

    2005-01-01

    ...) utilizing the APG Standardized UXO Technology Demonstration Site Open Field. Scoring Records have been coordinated by Larry Overbay and the Standardized UXO Technology Demonstration Site Scoring Committee...

  15. Standardized UXO Technology Demonstration Site, Open Field Scoring Record No. 897

    National Research Council Canada - National Science Library

    Burch, William; Fling, Rick; McClung, Christina

    2008-01-01

    ...) utilizing the APG Standardized UXO Technology Demonstration Site Open Field. This Scoring Record was coordinated by William Burch and the Standardized UXO Technology Demonstration Site Scoring Committee...

  16. Standardized UXO Technology Demonstration Site Open Field Scoring Record No. 442

    National Research Council Canada - National Science Library

    Overbay, Larry, Jr; Boutin, Matthew; Archiable, Robert; Fling, Rick; McClung, Christina; Robitaille, George

    2005-01-01

    ...) unitizing the YPG Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbay and the Standardized UXO Technology Demonstration Site Scoring Committee...

  17. Standardized UXO Technology Demonstration Site, Open Field Scoring Record Number 638

    National Research Council Canada - National Science Library

    Overbay, Larry, Jr; Robitaille, George; Boutin, Matthew; Archiable, Robert; McClung, Christina

    2005-01-01

    ...) utilizing the YPG Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbay and the Standardized UXO Technology Demonstration Site Scoring Committee...

  18. Standardized UXO Technology Demonstration Site Open Field Scoring Record No. 857

    National Research Council Canada - National Science Library

    Fling, Rick; McClung, Christina; Banta, Matthew; Burch, William; McDonnell, Patrick

    2007-01-01

    ...) utilizing the APG Standardized UXO Technology Demonstration Site Open Field. This Scoring Record was coordinated by Dennis Teefy and the Standardized UXO Technology Demonstration Site Scoring Committee...

  19. Identifying open magnetic field regions of the Sun and their heliospheric counterparts

    Science.gov (United States)

    Krista, L. D.; Reinard, A.

    2017-12-01

    Open magnetic regions on the Sun are either long-lived (coronal holes) or transient (dimmings) in nature. Both phenomena are fundamental to our understanding of the solar behavior as a whole. Coronal holes are the sources of high-speed solar wind streams that cause recurrent geomagnetic storms. Furthermore, the variation of coronal hole properties (area, location, magnetic field strength) over the solar activity cycle is an important marker of the global evolution of the solar magnetic field. Dimming regions, on the other hand, are short-lived coronal holes that often emerge in the wake of solar eruptions. By analyzing their physical properties and their temporal evolution, we aim to understand their connection with their eruptive counterparts (flares and coronal mass ejections) and predict the possibility of a geomagnetic storm. The author developed the Coronal Hole Automated Recognition and Monitoring (CHARM) and the Coronal Dimming Tracker (CoDiT) algorithms. These tools not only identify but track the evolution of open magnetic field regions. CHARM also provides daily coronal hole maps, that are used for forecasts at the NOAA Space Weather Prediction Center. Our goal is to better understand the processes that give rise to eruptive and non-eruptive open field regions and investigate how these regions evolve over time and influence space weather.

  20. Standardized UXO Technology Demonstration Site. Open Field Scoring Record Number 154

    National Research Council Canada - National Science Library

    Overbay, Larry

    2004-01-01

    ...) utilizing the APG Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Site Scoring Committee...

  1. Standardized UXO Technology Demonstration Site, Open Field Scoring Record Number 379

    National Research Council Canada - National Science Library

    Overbay, Larry; Robitaille, George

    2005-01-01

    ... (UXO) utilizing the APG Standardized UXO Technology Demonstration Site Open Field. Scoring Records have been coordinated by Larry Overbay and the Standardized UXO Technology Demonstration Site Scoring Committee...

  2. Standardized UXO Technology Demonstration Site Open Field Scoring Record Number 354

    National Research Council Canada - National Science Library

    Overbay, Larry, Jr; Archiable, Robert; McClung, Christina

    2005-01-01

    ...) utilizing the YPG Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Site Scoring Committee...

  3. Standardized UXO Technology Demonstration Site Open Field Scoring Record No. 311

    National Research Council Canada - National Science Library

    Overbay, Larry, Jr; Boutin, Matthew; Fling, Rick; McClung, Christina; Robitaille, George

    2005-01-01

    ...) utilizing the APG Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Site Scoring Committee...

  4. Standardized UXO Technology Demonstration Site Open Field Scoring Record Number 129

    National Research Council Canada - National Science Library

    Overbay, Larry

    2004-01-01

    ...) utilizing the APO Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Site Scoring Committee...

  5. Standardized UXO Technology Demonstration Site, Open Field Scoring Record Number 229

    National Research Council Canada - National Science Library

    Overbay, Larry, Jr; Boutin, Matthew; Fling, Rick; McClung, Christina; Robitaille, George

    2005-01-01

    ...) utilizing the APG Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Site Scoring Committee...

  6. Standardized UXO Technology Demonstration Site, Open Field Scoring Record Number 411

    National Research Council Canada - National Science Library

    Overbay, Larry; Robitaille, George

    2005-01-01

    ...) utilizing the APG Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Site Scoring Committee...

  7. Standardized UXO Technology Demonstration Site Open Field Scoring Record Number 169

    National Research Council Canada - National Science Library

    Overbay, Larry; Archiable, Robert; McClung, Christina; Robitaille, George

    2005-01-01

    ...) utilizing the YPG Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Site Scoring Committee...

  8. Standardized UXO Technology Demonstration Site Open Field Scoring Record Number 201

    National Research Council Canada - National Science Library

    Overbay, Larry, Jr; Fling, Rick; Robitaille, George

    2004-01-01

    ...) utilizing the APG Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Site Scoring Committee...

  9. Standardized UXO Technology Demonstration Site Open Field Scoring Record Number 165

    National Research Council Canada - National Science Library

    Overbay, Larry

    2004-01-01

    ...) utilizing the APO Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Site Scoring Committee...

  10. Peripubertal castration of male rats, adult open field ambulation and partner preference behavior.

    Science.gov (United States)

    Brand, T; Slob, A K

    1988-09-15

    The validity of the hypothesis put forward earlier, that testicular secretions during puberty have an organizing effect on open field ambulation was examined. Male rats were castrated or sham-operated at days 21, 43 or 70. At the age of 17 weeks the males were tested in an automated, octagonal open field (3 consecutive days, 3 min/day) for locomotor activity. Male rats castrated at day 21 or day 43 ambulated more than sham-castrated controls. Males castrated at day 70 did not differ from sham-castrated controls. It thus appears that pubertal testicular secretion(s) organize adult open field locomotor activity in male rats. From 18 weeks of age partner preference behavior was tested in the same open field apparatus with one adjacent cage containing an ovariectomized female and an opposite one containing an ovariectomized female brought into heat. The females in the adjacent cages were separated from the experimental males in the octagonal cage by wire mesh. Peripubertally castrated males did not show a clear-cut partner preference, whereas the intact males preferred the vicinity of the estrous female. There were no differences among the males castrated either before, during or after puberty. Testosterone treatment (crystalline T in silastic capsules) caused peripubertally castrated males to prefer the estrous female. Thus, adult partner preference behavior does not seem to be organized by peripubertal testicular androgens.

  11. Standardized UXO Technology Demonstration Site Open Field Scoring Record Number 245

    National Research Council Canada - National Science Library

    Overbay, Larry

    2005-01-01

    ... (UXO) utilizing the YPG Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Site Scoring Committee...

  12. Standardized UXO Technology Demonstration Site Open Field Scoring Record Number 675

    National Research Council Canada - National Science Library

    Overbay, Larry; Robitaille, George

    2005-01-01

    ... (UXO) utilizing the APG Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Site Scoring Committee...

  13. Long Term Results of Visual Field Progression Analysis in Open Angle Glaucoma Patients Under Treatment.

    Science.gov (United States)

    Kocatürk, Tolga; Bekmez, Sinan; Katrancı, Merve; Çakmak, Harun; Dayanır, Volkan

    2015-01-01

    To evaluate visual field progression with trend and event analysis in open angle glaucoma patients under treatment. Fifteen year follow-up results of 408 eyes of 217 glaucoma patients who were followed at Adnan Menderes University, Department of Ophthalmology between 1998 and 2013 were analyzed retrospectively. Visual field data were collected for Mean Deviation (MD), Visual Field Index (VFI), and event occurrence. There were 146 primary open-angle glaucoma (POAG), 123 pseudoexfoliative glaucoma (XFG) and 139 normal tension glaucoma (NTG) eyes. MD showed significant change in all diagnostic groups (pfield indices. We herein report our fifteen year follow-up results in open angle glaucoma.

  14. Function of the centromedial amygdala in reward devaluation and open-field activity.

    Science.gov (United States)

    Kawasaki, K; Glueck, A C; Annicchiarico, I; Papini, M R

    2015-09-10

    The present research aimed at determining the role played by the amygdala in reward devaluation using transient inactivation induced by lidocaine microinfusions into the centromedial region. Two situations involving reward devaluation were tested in rats: consummatory successive negative contrast (cSNC) and anticipatory negative contrast (ANC). In cSNC, rats exposed to a downshift from 32% to 4% sucrose consume less 4% sucrose than rats always exposed to 4% sucrose. Extensive evidence suggests that reward devaluation in the cSNC situation is accompanied by negative emotion. In ANC, rats consume less 4% sucrose when each session is closely followed by access to 32% sucrose rather than by 4% sucrose. Evidence suggests that reward devaluation in the ANC situation does not involve negative emotions; rather, ANC appears to involve Pavlovian anticipation of the higher value solution. To test the effects of lidocaine microinfusions in a situation known to induce negative emotion, but unrelated to reward devaluation, animals were also exposed to a lighted open field. Centromedial amygdala inactivation reduced the cSNC effect and increased exploratory behavior in the open field, both effects consistent with a reduction in negative emotional state. However, no detectable effects of amygdala inactivation were observed in the ANC situation. These results suggest that, first, the function of the amygdala is not unique to reward devaluation and, second, it is concerned with tagging the devaluation experience with aversive valence. Copyright © 2015 IBRO. Published by Elsevier Ltd. All rights reserved.

  15. Analytic study of nonperturbative solutions in open string field theory

    International Nuclear Information System (INIS)

    Bars, I.; Kishimoto, I.; Matsuo, Y.

    2003-01-01

    We propose an analytic framework to study the nonperturbative solutions of Witten's open string field theory. The method is based on the Moyal star formulation where the kinetic term can be split into two parts. The first one describes the spectrum of two identical half strings which are independent from each other. The second one, which we call midpoint correction, shifts the half string spectrum to that of the standard open string. We show that the nonlinear equation of motion of string field theory is exactly solvable at zeroth order in the midpoint correction. An infinite number of solutions are classified in terms of projection operators. Among them, there exists only one stable solution which is identical to the standard butterfly state. We include the effect of the midpoint correction around each exact zeroth order solution as a perturbation expansion which can be formally summed to the complete exact solution

  16. OER research agenda discussion for Open Education 2006 (29/9) discussing the development of a research agenda for Open Educational Resources

    CSIR Research Space (South Africa)

    Bateman, P

    2006-01-01

    Full Text Available stream_source_info Bateman_2006_D.pdf.txt stream_content_type text/plain stream_size 17977 Content-Encoding UTF-8 stream_name Bateman_2006_D.pdf.txt Content-Type text/plain; charset=UTF-8     International Institute for Educational... Planning OER Research Agenda Discussion  for OpenEducation2006 (29/9) Discussing the development of a research agenda for Open  Educational Resources Convened by the IIEP Co­facilitated by  Peter Bateman (AVU)  and  Kim...

  17. A note on T-duality, open strings in B-field background and canonical transformations

    International Nuclear Information System (INIS)

    Sheikh-Jabbari, M.M.

    1999-11-01

    In this paper we study T-duality for open strings ending on branes with non-zero B-field on them from the point of view of canonical transformations. For the particular case of type II strings on the two torus we show that the Sl(2, Z) N transformations can be understood as a sub-class of canonical transformations on the open strings in the B-field background. (author)

  18. Exact marginality in open string field theory. A general framework

    International Nuclear Information System (INIS)

    Kiermaier, M.

    2007-07-01

    We construct analytic solutions of open bosonic string field theory for any exactly marginal deformation in any boundary conformal field theory when properly renormalized operator products of the marginal operator are given. We explicitly provide such renormalized operator products for a class of marginal deformations which include the deformations of flat D-branes in flat backgrounds by constant massless modes of the gauge field and of the scalar fields on the D-branes, the cosine potential for a space-like coordinate, and the hyperbolic cosine potential for the time-like coordinate. In our construction we use integrated vertex operators, which are closely related to finite deformations in boundary conformal field theory, while previous analytic solutions were based on unintegrated vertex operators. We also introduce a modified star product to formulate string field theory around the deformed background. (orig.)

  19. Pushing Firm Boundaries through Research and Open Innovation

    DEFF Research Database (Denmark)

    Borup Lynggaard, Aviaja

    2011-01-01

    provide into the company and bring forward the effect it has inside a company when performing open innovation together with research partners. We seek to bring forward how performing university-research collaboration can also change the practices inside a company and thus push the firm boundaries in new...

  20. On Field Theory of Open Strings, Tachyon Condensation and Closed Strings

    OpenAIRE

    Shatashvili, Samson L.

    2001-01-01

    I review the physical properties of different vacua in the background independent open string field theory. Talk presented at Strings 2001, Mumbai, India, http://theory.theory.tifr.res.in/strings/Proceedings/#sha-s.

  1. The Open Business Model: Understanding an Emerging Concept

    OpenAIRE

    Weiblen Tobias

    2014-01-01

    Along with the emergence of phenomena such as value co-creation, firm networks, and open innovation, open business models have achieved growing attention in research. Scholars from different fields use the open business model, largely without providing a definition. This has led to an overall lack of clarity of the concept itself. Based on a comprehensive review of scholarly literature in the field, commonalities and differences in the perceived nature of the open business model are carved ou...

  2. Effects of a single inhalative exposure to formaldehyde on the open field behavior of mice.

    Science.gov (United States)

    Malek, Fathi A; Möritz, Klaus-Uwe; Fanghänel, Jochen

    2004-02-01

    The effects of formaldehyde on the explorative behavior and locomotor activity of mice after a single inhalative exposure were examined in an open field. Adult male mice were exposed to approximately 1.1 ppm, 2.3 ppm, or 5.2 ppm formaldehyde vapour for 2 hours and the open field test was carried out two hours after the end of exposure (trial 1) and repeated 24 hours thereafter (trial 2). The following behavioral parameters were quantitatively examined: numbers of crossed floor squares (inner, peripheral, total), sniffing, grooming, rearing, climbing, and incidence of fecal boli. The results of the first trial revealed that the motion activity was significantly reduced in all exposed groups. In the 1.1 ppm group, the frequency of rearing was reduced and that of floor sniffing increased. The exposure to the two higher formaldehyde concentrations caused a significant decrease in total numbers of floor squares crossed by the subjects, air sniffing, and rearing. The open field test on the next day (trial 2) showed that the frequencies of floor sniffing, grooming, and rearing in all formaldehyde groups were significantly altered. In the 2.5 ppm group, an increased incidence of fecal boli was observed. From the results obtained, we conclude that the exposure of male mice to formaldehyde vapour affects their locomotor and explorative activity in the open field, and that some open field parameters are still altered in the exposed animals even after 24 hours.

  3. Open string Regge trajectory and its field theory limit

    International Nuclear Information System (INIS)

    Rojas, Francisco; Thorn, Charles B.

    2011-01-01

    We study the properties of the leading Regge trajectory in open string theory including the open string planar one-loop corrections. With SU(N) Chan-Paton factors, the sum over planar open string multiloop diagrams describes the 't Hooft limit N→∞ with Ng s 2 fixed. Our motivation is to improve the understanding of open string theory at finite α ' as a model of gauge field theories. SU(N) gauge theories in D space-time dimensions are described by requiring open strings to end on a stack of N Dp-branes of space-time dimension D=p+1. The large N leading trajectory α(t)=1+α ' t+Σ(t) can be extracted, through order g 2 , from the s→-∞ limit, at fixed t, of the four open string tree and planar loop diagrams. We analyze the t→0 behavior with the result that Σ(t)∼-Cg 2 (-α ' t) (D-4)/2 /(D-4). This result precisely tracks the 1-loop Reggeized gluon of gauge theory in D>4 space-time dimensions. In particular, for D→4 it reproduces the known infrared divergences of gauge theory in 4 dimensions with a Regge trajectory behaving as -ln(-α ' t). We also study Σ(t) in the limit t→-∞ and show that, when D ' t/(ln(-α ' t)) γ , where γ>0 depends on D and the number of massless scalars. Thus, as long as 4 ' t arbitrarily large. Finally we present the results of numerical calculations of Σ(t) for all negative t.

  4. A simple solvable model of quantum field theory of open strings

    International Nuclear Information System (INIS)

    Kazakov, V.A.; AN SSSR, Moscow

    1990-01-01

    A model of quantum field theory of open strings without any embedding (D=0) is solved. The world sheets of interacting strings are represented by dynamical planar graphs with dynamical holes of arbitrary sizes. The phenomenon of spontaneous tearing of the world sheet is noticed, which gives a singularity at zero coupling constant of string interaction. This phenomenon can be considered as a nonperturbative effect, similar to renormalons in planar field theories and is closely related to the α' → 0 limit of string field theories. (orig.)

  5. Persistent Identifiers for Field Expeditions: A Next Step for the US Oceanographic Research Fleet

    Science.gov (United States)

    Arko, Robert; Carbotte, Suzanne; Chandler, Cynthia; Smith, Shawn; Stocks, Karen

    2016-04-01

    Oceanographic research cruises are complex affairs, typically requiring an extensive effort to secure the funding, plan the experiment, and mobilize the field party. Yet cruises are not typically published online as first-class digital objects with persistent, citable identifiers linked to the scientific literature. The Rolling Deck to Repository (R2R; info@rvdata.us) program maintains a master catalog of oceanographic cruises for the United States research fleet, currently documenting over 6,000 expeditions on 37 active and retired vessels. In 2015, R2R started routinely publishing a Digital Object Identifier (DOI) for each completed cruise. Cruise DOIs, in turn, are linked to related persistent identifiers where available including the Open Researcher and Contributor ID (ORCID) for members of the science party, the International Geo Sample Number (IGSN) for physical specimens collected during the cruise, the Open Funder Registry (FundRef) codes that supported the experiment, and additional DOIs for datasets, journal articles, and other products resulting from the cruise. Publishing a persistent identifier for each field expedition will facilitate interoperability between the many different repositories that hold research products from cruises; will provide credit to the investigators who secured the funding and carried out the experiment; and will facilitate the gathering of fleet-wide altmetrics that demonstrate the broad impact of oceanographic research.

  6. Open access journals – what publishers offer, what researchers want

    CERN Document Server

    Dallmeier-Tiessen, Suenje; Goerner, Bettina; Hyppoelae, Jenni; Igo-Kemenes, Peter; Kahn, Deborah; Lamber, Simon; Lengenfelder, Anja; Leonard, Chris; Mele, Salvatore; Nowicka, Malgorzata; Polydoratou, Panayiota; Ross, David; Ruiz-Perez, Sergio; Schimmer, Ralf; Swaisland, Mark; van der Stelt, Wim

    2011-01-01

    The SOAP (Study of Open Access Publishing) project has analyzed the current supply and demand situation in the open access journal landscape. Starting from the Directory of Open Access Journals, several sources of data were considered, including journal websites and direct inquiries within the publishing industry to comprehensively map the present supply of online peer-reviewed OA journals. The demand for open access publishing is summarised, as assessed through a large-scale survey of researchers' opinions and attitudes. Some forty thousand answers were collected across disciplines and around the world, reflecting major support for the idea of open access, while highlighting drivers of and barriers to open access publishing.

  7. Open access publishing: a study of current practices in orthopaedic research.

    Science.gov (United States)

    Sabharwal, Sanjeeve; Patel, Nirav; Johal, Karanjeev

    2014-06-01

    Open access (OA) publications have changed the paradigm of dissemination of scientific research. Their benefits to low-income countries underline their value; however, critics question exorbitant publication fees as well as their effect on the peer review process and research quality. This study reports on the prevalence of OA publishing in orthopaedic research and compares benchmark citation indices as well as evidence quality derived from OA journals with conventional subscription based orthopaedic journals. All 63 orthopaedic journals listed in ISI's Web of Knowledge Journal Citation Report (JCR) were examined. Bibliometric data attributed to each journal for the year 2012 was acquired from the JCR. Studies that fulfilled the criteria of level I evidence were identified for each journal within PubMed. Individual journal websites were reviewed to identify their open access policy. A total of 38 (60.3 %) journals did not offer any form of OA publishing; however, 20 (31.7 %) hybrid journals were identified which offered authors the choice to publish their work as OA if a publication fee was paid. Only five (8 %) journals published all their articles as OA. There was variability amongst the different publication fees for OA articles. Journals that published OA articles did not differ from subscription based journals on the basis of 2012 impact factor, citation number, self citation proportion or the volume of level I evidence published (p > 0.05). OA journals are present in orthopaedic research, though in small numbers. Over a third of orthopaedic journals catalogued in the ISI Web of Knowledge JCR® are hybrid journals that provide authors with the opportunity to publish their articles as OA after a publication fee is paid. This study suggests equivalent importance and quality of articles between OA and subscription based orthopaedic journals based on bibliometric data and the volume of level I evidence produced. Orthopaedic researchers must recognize the

  8. Reframing Open Big Data

    DEFF Research Database (Denmark)

    Marton, Attila; Avital, Michel; Jensen, Tina Blegind

    2013-01-01

    Recent developments in the techniques and technologies of collecting, sharing and analysing data are challenging the field of information systems (IS) research let alone the boundaries of organizations and the established practices of decision-making. Coined ‘open data’ and ‘big data......’, these developments introduce an unprecedented level of societal and organizational engagement with the potential of computational data to generate new insights and information. Based on the commonalities shared by open data and big data, we develop a research framework that we refer to as open big data (OBD......) by employing the dimensions of ‘order’ and ‘relationality’. We argue that these dimensions offer a viable approach for IS research on open and big data because they address one of the core value propositions of IS; i.e. how to support organizing with computational data. We contrast these dimensions with two...

  9. Effects of nutmeg consumption on the open field locomotor activities ...

    African Journals Online (AJOL)

    ... was a steady significant difference (p < 0.05) in the behaviours of line crossing and walling. There was no much significant changes (P<0.05) in the behaviours of hinding, grooming and defeacation between the Treatments and Control groups of animals. Keywords: Nutmeg, Wistar rats, Open field, Locomotor activities ...

  10. Policy research institutions and the health SDGs: Open data ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Policy research institutions and the health SDGs: Open data platforms for ... This exercise will provide the opportunity to raise awareness of the SGDs and the ... IDRC is supporting research that studies the most effective ways to empower ...

  11. Access to Knowledge Southern Africa : Universities, Open Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Journal articles. Research productivity-visibility-accessibility and scholarly communication in Southern African universities. Download PDF ... Call for new OWSD Fellowships for Early Career Women Scientists now open. In partnership with ...

  12. Foraging enrichment modulates open field response to monosodium glutamate in mice.

    Science.gov (United States)

    Onaolapo, Olakunle J; Onaolapo, Adejoke Y; Akanmu, Moses A; Olayiwola, Gbola

    2015-07-01

    Environmental enrichment can enhance expression of species-specific behaviour. While foraging enrichment is encouraged in laboratory animals, its impact on novelty induced behaviour remain largely unknown. Here, we studied behavioural response of mice to acute and subchronic oral monosodium glutamate (MSG) in an open field with /without foraging enrichment. Adult male mice, assigned to five groups were administered vehicle (distilled water), or one of four selected doses of MSG (10, 20, 40 and 80 mg/kg) for 21 days. Open field novelty induced behaviours i.e. horizontal locomotion, rearing and grooming were assessed after the first and last doses of MSG. Results were analysed using MANOVA followed by Tukey HSD multiple comparison test and expressed as mean ± S.E.M. Following acute MSG administration without enrichment, locomotor activity reduced, grooming increased, while rearing activity reduced at lower doses and increased at higher doses. Subchronic administration without enrichment was associated with increased locomotor activity and reduction in grooming, rearing activity however still showed a biphasic response. Addition of enrichment with acute administration resulted in sustained reduction in locomotor and rearing activities with a biphasic grooming response. Subchronically, there was reduction in horizontal locomotion, biphasic rearing response and sustained increase in grooming activity. Behavioural response to varying doses of MSG as observed in the open field is affected by modifications such as foraging enrichment, which can reverse or dampen the central effects seen irrespective of duration of administration.

  13. Finasteride inhibited brain dopaminergic system and open-field behaviors in adolescent male rats.

    Science.gov (United States)

    Li, Li; Kang, Yun-Xiao; Ji, Xiao-Ming; Li, Ying-Kun; Li, Shuang-Cheng; Zhang, Xiang-Jian; Cui, Hui-Xian; Shi, Ge-Ming

    2018-02-01

    Finasteride inhibits the conversion of testosterone to dihydrotestosterone. Because androgen regulates dopaminergic system in the brain, it could be hypothesized that finasteride may inhibit dopaminergic system. The present study therefore investigates the effects of finasteride in adolescent and early developmental rats on dopaminergic system, including contents of dopamine and its metabolites (dihydroxy phenyl acetic acid and homovanillic acid) and tyrosine hydroxylase expressions both at gene and protein levels. Meanwhile, open-field behaviors of the rats are examined because of the regulatory effect of dopaminergic system on the behaviors. Open-field behaviors were evaluated by exploratory and motor behaviors. Dopamine and its metabolites were assayed by liquid chromatography-mass spectrometry. Tyrosine hydroxylase mRNA and protein expressions were determined by real-time qRT-PCR and western blot, respectively. It was found that in adolescent male rats, administration of finasteride at doses of 25 and 50 mg/kg for 14 days dose dependently inhibited open-field behaviors, reduced contents of dopamine and its metabolites in frontal cortex, hippocampus, caudate putamen, nucleus accumbens, and down-regulated tyrosine hydroxylase mRNA and protein expressions in substantia nigra and ventral tegmental area. However, there was no significant change of these parameters in early developmental rats after finasteride treatment. These results suggest that finasteride inhibits dopaminergic system and open-field behaviors in adolescent male rats by inhibiting the conversion of testosterone to dihydrotestosterone, and imply finasteride as a potential therapeutic option for neuropsychiatric disorders associated with hyperactivities of dopaminergic system and androgen. © 2017 John Wiley & Sons Ltd.

  14. Effects of magnetic field exposure on open field behaviour and nociceptive responses in mice.

    Science.gov (United States)

    Del Seppia, Cristina; Mezzasalma, Lorena; Choleris, Elena; Luschi, Paolo; Ghione, Sergio

    2003-09-15

    Results of previous studies have shown that nociceptive sensitivity in male C57 mice is enhanced by exposure to a regular 37 Hz or an irregularly varying (field. In order to test whether these fields affect more generally mouse behaviour, we placed Swiss CD-1 mice in a novel environment (open field test) and exposed them for 2 h to these two different magnetic field conditions. Hence, we analysed how duration and time course of various behavioural patterns (i.e. exploration, rear, edge chew, self-groom, sit, walk and sleep) and nociceptive sensitivity had been affected by such exposure. Nociceptive sensitivity was significantly greater in magnetically treated mice than in controls. The overall time spent in exploratory activities was significantly shorter in both magnetically treated groups (time), than in controls (42%). Conversely, the time spent in sleeping was markedly longer in the treated groups (both 27% of total time) than in controls (11%). These results suggest that exposure to altered magnetic fields induce a more rapid habituation to a novel environment.

  15. Restudy of the open-superstring tree amplitudes by looking at their field-theoretical limits

    International Nuclear Information System (INIS)

    Hsu, R.; Yeung, W.B.; Yu, H.L.

    1987-01-01

    We carry out complete computations of some open- and closed-superstring tree amplitudes by using the bosonized covariant vertices. Some open-superstring amplitudes so obtained are shown to be different from those obtained in the light-cone gauge approach by some numerical factors. The low-energy limits of our five open-superstring amplitudes are then shown to match the five super Yang-Mills field amplitudes while the five light-cone gauge open-superstring amplitudes fail to do so

  16. Dissipation and enantioselective degradation of plant growth retardants paclobutrazol and uniconazole in open field, greenhouse, and laboratory soils.

    Science.gov (United States)

    Wu, Chengwang; Sun, Jianqiang; Zhang, Anping; Liu, Weiping

    2013-01-15

    Greenhouses are increasingly important in human food supply. Pesticides used in greenhouses play important roles in horticulture; however, little is known about their behavior in greenhouse environments. This work investigates the dissipation and enantioselctive degradation of plant growth retardants including paclobutrazol and uniconazole in soils under three conditions (i.e., open field, greenhouse, and laboratory). The dissipation and enantioselective degradation of paclobutrazol and uniconazole in greenhouse were different from those in open field; they were more persistent in greenhouse than in open field soil. Leaching produced by rainfall is responsible for the difference in dissipation. Thus, local environmental impacts may occur more easily inside greenhouses, while groundwater may be more contaminated in open field. Spike concentrations of 5, 10, and 20 times the concentrations of native residues were tested for the enantioselective dissipation of the two pesticides; the most potent enantioselective degradation of paclobutrazol and uniconazole occurred at the 10 times that of the native residues in the greenhouse environments and at 20 times native residues in open field environments. The higher soil activity in greenhouses than in open fields was thought to be responsible for such a difference. The environmental risk and regulation of paclobutrazol and uniconazole should be considered at the enantiomeric level.

  17. The power of research exploration within education: lessons from an international field hydrology course

    Science.gov (United States)

    Abou Najm, M. R.; Stewart, R. D.; Rupp, D. E.; Selker, J. S.; Lane, J. W.; Casanova, F.; Arumí, J.; Rivera, D.

    2011-12-01

    Educating the next generation of scientists requires new educational methods and unconventional approaches to facilitate the interdisciplinary scholarship required to cope with fast-paced developments in the geosciences. We believe incorporation of field training with active research missions is an effective educational model. By participating in active research and open science dialogue, students are exposed to real-world examples of the principles and processes of complex systems in a manner that allows them to develop a deeper understanding of the subject. We find students are highly motivated by the knowledge that data they collect will advance the research mission; such an environment stokes their passions and imaginations and allows the students to explore the roots of their interest in geoscience. In this context, a two-week educational field course on hydrologic processes and measurements was integrated with ongoing research in Chile to understand the effect of soil shrinkage and swelling properties on watershed hydrologic response. Students witnessed the iterative process of field-experiment design and became part of science in the making. They experienced the complexity of field work and developed problem-solving skills through the myriad of challenges presented in the acquisition of field data in a remote area. All of these factors contributed to an atmosphere of creativity that led to an outstanding research and educational experience. We find the coupling of field training with active research to be extremely rewarding, and time- and cost-effective education in this fast-paced and cost-cautious age.

  18. CERN Open Data Portal - Improving usability and user experience of CMS Open Data research tools.

    CERN Document Server

    Hirvonsalo, Harri

    2015-01-01

    This report summarizes the work I have done during my assignment as participant of CERN Summer Students 2015 programme. Main goal of my Summer Student project was to lower the bar for people to start utilizing open data that CMS experiment has released in November 2014 to CERN Open Data Portal (http://opendata.cern.ch). Project included various working packages and tasks, such as: -Determine the obstacles that potential users of CMS research oriented open data who don’t have previous knowledge about internal workflow of analysis tasks at CMS experiment would run into. -Produce more introductory material and tutorials for conducting basic physics analyses with CMSSW to CERN Open Data Portal. -Study the feasibility of podio-framework (https://github.com/hegner/podio) for CMS Open Data users. The project work was done under the supervision of Kati Lassila-Perini whom I thank greatly for her help, patience and support.

  19. Counterstreaming solar wind halo electron events on open field lines?

    Science.gov (United States)

    Gosling, J. T.; Mccomas, D. J.; Phillips, J. L.

    1992-01-01

    Counterstreaming solar wind halo electron events have been identified as a common 1 AU signature of coronal mass ejection events, and have generally been interpreted as indicative of closed magnetic field topologies, i.e., magnetic loops or flux ropes rooted at both ends in the Sun, or detached plasmoids. In this paper we examine the possibility that these events may instead occur preferentially on open field lines, and that counterstreaming results from reflection or injection behind interplanetary shocks or from mirroring from regions of compressed magnetic field farther out in the heliosphere. We conclude that neither of these suggested sources of counterstreaming electron beams is viable and that the best interpretation of observed counterstreaming electron events in the solar wind remains that of passage of closed field structures.

  20. Remote Laboratory and Animal Behaviour: An Interactive Open Field System

    Science.gov (United States)

    Fiore, Lorenzo; Ratti, Giovannino

    2007-01-01

    Remote laboratories can provide distant learners with practical acquisitions which would otherwise remain precluded. Our proposal here is a remote laboratory on a behavioural test (open field test), with the aim of introducing learners to the observation and analysis of stereotyped behaviour in animals. A real-time video of a mouse in an…

  1. Keldysh field theory for driven open quantum systems.

    Science.gov (United States)

    Sieberer, L M; Buchhold, M; Diehl, S

    2016-09-01

    Recent experimental developments in diverse areas-ranging from cold atomic gases to light-driven semiconductors to microcavity arrays-move systems into the focus which are located on the interface of quantum optics, many-body physics and statistical mechanics. They share in common that coherent and driven-dissipative quantum dynamics occur on an equal footing, creating genuine non-equilibrium scenarios without immediate counterpart in equilibrium condensed matter physics. This concerns both their non-thermal stationary states and their many-body time evolution. It is a challenge to theory to identify novel instances of universal emergent macroscopic phenomena, which are tied unambiguously and in an observable way to the microscopic drive conditions. In this review, we discuss some recent results in this direction. Moreover, we provide a systematic introduction to the open system Keldysh functional integral approach, which is the proper technical tool to accomplish a merger of quantum optics and many-body physics, and leverages the power of modern quantum field theory to driven open quantum systems.

  2. Attracted to open access journals: A bibliometric author analysis in the field of biology

    DEFF Research Database (Denmark)

    Faber Frandsen, Tove

    2009-01-01

    Purpose - Scholars from developing countries have limited access to research publications due to expensive subscription costs. However, the open access movement is challenging the constraint to access. Consequently, researchers in developing countries are often mentioned as major recipients...... of the benefits when advocating open access (OA). One of the implications of that argument is that authors from developing countries are more likely to perceive open access positively than authors from developed countries. The present study aims to investigate the use of open access by researchers from developing...... countries and is thus a supplement to the existing author surveys and interviews. Design/methodology/approach - Bibliometric analyses of both publishing behaviour and citing behaviour in relation to OA publishing provides evidence of the impact of open access on developing countries. Findings - The results...

  3. Research on countermeasures to global environment change in the field of urban planning

    Energy Technology Data Exchange (ETDEWEB)

    Kawanaka, Takashi [Building Research Inst., Tsukuba-shi, Ibaraki (Japan)

    1993-12-31

    There are a lot of research themes in the field of urban planning and related fields as mitigation of global environment change. Main theme is reduction method of CO{sub 2} gas emission as a countermeasure against global warming. Some groups research on estimation of CO{sub 2} emission caused by construction activities both in building engineering and civil engineering and also on evaluation of countermeasures. They investigate reduction of CO{sub 2} emission by fossil fuel combustion and by building materials (cement, steel and so on) production process. But we cannot use data fitted to a spatial scale of urban planning. Many researches are focused on nation wide analysis. We, BRI, make a study of {open_quotes}Research on CO{sub 2} Emission in Urban Development and the Control Technologies{close_quotes} as will be seen later at 2. (2). There are two ways of research to reduce CO{sub 2} emission caused by daily activities to urban planning field. One is research on positive utilizing of natural environment in urban areas without depending to energy consuming artificial facilities. There is a research on mitigation of heat island phenomenon for instance. The other ways are research on improvement of energy consumption effect and on reusing of wasted energy In energy consuming type urban space for instance. There s a research on promoting District Heating and Cooling (DHC) and cogeneration.

  4. Open innovation in health care: analysis of an open health platform.

    Science.gov (United States)

    Bullinger, Angelika C; Rass, Matthias; Adamczyk, Sabrina; Moeslein, Kathrin M; Sohn, Stefan

    2012-05-01

    Today, integration of the public in research and development in health care is seen as essential for the advancement of innovation. This is a paradigmatic shift away from the traditional assumption that solely health care professionals are able to devise, develop, and disseminate novel concepts and solutions in health care. The present study builds on research in the field of open innovation to investigate the adoption of an open health platform by patients, care givers, physicians, family members, and the interested public. Results suggest that open innovation practices in health care lead to interesting innovation outcomes and are well accepted by participants. During the first three months, 803 participants of the open health platform submitted challenges and solutions and intensively communicated by exchanging 1454 personal messages and 366 comments. Analysis of communication content shows that empathic support and exchange of information are important elements of communication on the platform. The study presents first evidence for the suitability of open innovation practices to integrate the general public in health care research in order to foster both innovation outcomes and empathic support. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  5. Open Online Research: Developing Software and Method for Collaborative Interpretation

    Directory of Open Access Journals (Sweden)

    Christian Bröer

    2016-09-01

    Full Text Available Inspired by the potentials of web-based collaboration, in 2014, a group of social scientists, students and information specialists started tinkering with software and methodology for open online collaborative research. The results of their research led to a gathering of academics at the #ethnography Conference Amsterdam 2014, where new material was collected, shared and collaboratively interpreted. Following the conference, they continued to develop software and methodology. In this contribution, we report on the aims, methodology, inspiring examples, caveats and results from testing several prototypes of open online research software. We conclude that open online collaborative interpretation is both feasible and desirable. Dialogue and reflexivity, we hold, are able to transcend separated perspectives and stimulate agreement on a set of distinct interpretations; they simultaneously respect the multiplicity of understandings of social phenomena whilst bringing order into this diversity. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs160327

  6. How to create successful Open Hardware projects - About White Rabbits and open fields

    CERN Document Server

    van der Bij, E; Lewis, J; Stana, T; Wlostowski, T; Gousiou, E; Serrano, J; Arruat, M; Lipinski, M M; Daniluk, G; Voumard, N; Cattin, M

    2013-01-01

    CERN's accelerator control group has embraced "Open Hardware" (OH) to facilitate peer review, avoid vendor lock-in and make support tasks scalable. A web-based tool for easing collaborative work was set up and the CERN OH Licence was created. New ADC, TDC, fine delay and carrier cards based on VITA and PCI-SIG standards were designed and drivers for Linux were written. Often industry was paid for developments, while quality and documentation was controlled by CERN. An innovative timing network was also developed with the OH paradigm. Industry now sells and supports these designs that find their way into new fields.

  7. The Importance of Connecting Open Innovation to Strategy

    NARCIS (Netherlands)

    Vanhaverbeke, Wim; Roijakkers, Nadine; Lorenz, A.; Chesbrough, Henry W.

    2017-01-01

    Companies that are experienced in open innovation integrate open innovation activities as part of their strategy. By contrast, open innovation research has not been adequately integrated into the strategy literature and vice versa. In this chapter, we discuss a number of existing strategy fields

  8. Magnetic field propagation in a two ion species planar plasma opening switch

    International Nuclear Information System (INIS)

    Strauss, H. R.; Doron, R.; Arad, R.; Rubinstein, B.; Maron, Y.; Fruchtman, A.

    2007-01-01

    Three fluid plasma evolution equations are applied to the problem of magnetic field propagation in a planar plasma opening switch. For certain initial conditions in which Hall parameter H∼1, magnetic field penetration due to the Hall field, initially, as expected, either opposes or adds to the hydromagnetic pushing, depending on the polarity of the magnetic field relative to the density gradient. Later, however, the plasma pushing by the magnetic field is found in the case studied here to modify the plasma density in a way that the density gradient tends to align with the magnetic field gradient, effectively turning off the Hall effect. The penetration of the magnetic field then ceases and plasma pushing becomes the dominant process

  9. Place and Response Learning in the Open-field Tower Maze.

    Science.gov (United States)

    Lipatova, Olga; Campolattaro, Matthew M; Toufexis, Donna J; Mabry, Erin A

    2015-10-28

    This protocol describes how the Open-field Tower Maze (OFTM) paradigm is used to study spatial learning in rodents. This maze is especially useful for examining how rats learn to use a place- or response-learning to successfully navigate in an open-field arena. Additionally, this protocol describes how the OFTM differs from other behavioral maze paradigms that are commonly used to study spatial learning in rodents. The OFTM described in this article was adapted from the one previously described by Cole, Clipperton, and Walt (2007). Specifically, the OFTM was created to test spatial learning in rodents without the experimenter having to consider how "stress" might play a role as a confounding variable. Experiments have shown that stress-alone can significantly affect cognitive function(1). The representative results section contains data from an experiment that used the OFTM to examine the effects of estradiol treatment on place- and response-learning in adult female Sprague Dawley rats(2). Future studies will be designed to examine the role of the hippocampus and striatum in place- and response-learning in the OFTM.

  10. open-quotes High magnetic fields in the USAclose quotes

    International Nuclear Information System (INIS)

    Campbell, L.J.; Parkin, D.M.; Crow, J.E.; Schneider-Muntau, H.J.; Sullivan, N.S.

    1994-01-01

    During the past thirty years research using high magnetic fields has technically evolved in the manner, but not the magnitude, of the so-called big science areas of particle physics, plasma physics, neutron scattering, synchrotron light scattering, and astronomy. Starting from the laboratories of individual researchers it moved to a few larger universities, then to centralized national facilities with research and maintenance staffs, and, finally, to joint international ventures to build unique facilities, as illustrated by the subject of this conference. To better understand the nature of this type of research and its societal justification it is helpful to compare it, in general terms, with the aforementioned big-science fields. High magnetic field research differs from particle physics, plasma physics, and astronomy in three respects: (1) It is generic research that cuts across a wide range of scientific disciplines in physics, chemistry, biology, medicine, and engineering; (2) It studies materials and processes that are relevant for a variety of technological applications and it gives insight into biological processes; (3) It has produced, at least, comparably significant results with incomparably smaller resources. Unlike neutron and synchrotron light scattering, which probe matter, high magnetic fields change the thermodynamic state of matter. This change of state is fundamental and independent of other state variables, such as pressure and temperature. After the magnetic field is applied, various techniques are then used to study the new state

  11. Performance of Ductless Personalized Ventilation in Open-Plan Office - Field Survey

    DEFF Research Database (Denmark)

    Dalewski, Mariusz; Ezzat Khalifa, H.; Melikov, Arsen Krikor

    2013-01-01

    A field survey was conducted in an architectural company located in Syracuse, USA. 54 employees who participated in the survey performed mostly design work. Large open-plan office and several single offices ventilated by displacement air distribution were included in the survey. Ductless...

  12. Exploratory behaviour in the open field test adapted for larval zebrafish: impact of environmental complexity.

    Science.gov (United States)

    Ahmad, Farooq; Richardson, Michael K

    2013-01-01

    This study aimed to develop and characterize a novel (standard) open field test adapted for larval zebrafish. We also developed and characterized a variant of the same assay consisting of a colour-enriched open field; this was used to assess the impact of environmental complexity on patterns of exploratory behaviours as well to determine natural colour preference/avoidance. We report the following main findings: (1) zebrafish larvae display characteristic patterns of exploratory behaviours in the standard open field, such as thigmotaxis/centre avoidance; (2) environmental complexity (i.e. presence of colours) differentially affects patterns of exploratory behaviours and greatly attenuates natural zone preference; (3) larvae displayed the ability to discriminate colours. As reported previously in adult zebrafish, larvae showed avoidance towards blue and black; however, in contrast to the reported adult behaviour, larvae displayed avoidance towards red. Avoidance towards yellow and preference for green and orange are shown for the first time, (4) compared to standard open field tests, exposure to the colour-enriched open field resulted in an enhanced expression of anxiety-like behaviours. To conclude, we not only developed and adapted a traditional rodent behavioural assay that serves as a gold standard in preclinical drug screening, but we also provide a version of the same test that affords the possibility to investigate the impact of environmental stress on behaviour in larval zebrafish while representing the first test for assessment of natural colour preference/avoidance in larval zebrafish. In the future, these assays will improve preclinical drug screening methodologies towards the goal to uncover novel drugs. This article is part of a Special Issue entitled: insert SI title. Copyright © 2012 Elsevier B.V. All rights reserved.

  13. Rolling Deck to Repository (R2R): Standards and Semantics for Open Access to Research Data

    Science.gov (United States)

    Arko, Robert; Carbotte, Suzanne; Chandler, Cynthia; Smith, Shawn; Stocks, Karen

    2015-04-01

    In recent years, a growing number of funding agencies and professional societies have issued policies calling for open access to research data. The Rolling Deck to Repository (R2R) program is working to ensure open access to the environmental sensor data routinely acquired by the U.S. academic research fleet. Currently 25 vessels deliver 7 terabytes of data to R2R each year, acquired from a suite of geophysical, oceanographic, meteorological, and navigational sensors on over 400 cruises worldwide. R2R is working to ensure these data are preserved in trusted repositories, discoverable via standard protocols, and adequately documented for reuse. R2R maintains a master catalog of cruises for the U.S. academic research fleet, currently holding essential documentation for over 3,800 expeditions including vessel and cruise identifiers, start/end dates and ports, project titles and funding awards, science parties, dataset inventories with instrument types and file formats, data quality assessments, and links to related content at other repositories. A Digital Object Identifier (DOI) is published for 1) each cruise, 2) each original field sensor dataset, 3) each post-field data product such as quality-controlled shiptrack navigation produced by the R2R program, and 4) each document such as a cruise report submitted by the science party. Scientists are linked to personal identifiers, such as the Open Researcher and Contributor ID (ORCID), where known. Using standard global identifiers such as DOIs and ORCIDs facilitates linking with journal publications and generation of citation metrics. Since its inception, the R2R program has worked in close collaboration with other data repositories in the development of shared semantics for oceanographic research. The R2R cruise catalog uses community-standard terms and definitions hosted by the NERC Vocabulary Server, and publishes ISO metadata records for each cruise that use community-standard profiles developed with the NOAA Data

  14. Open Data in Global Environmental Research: The Belmont Forum’s Open Data Survey

    Science.gov (United States)

    Schmidt, Birgit; Gemeinholzer, Birgit; Treloar, Andrew

    2016-01-01

    This paper presents the findings of the Belmont Forum’s survey on Open Data which targeted the global environmental research and data infrastructure community. It highlights users’ perceptions of the term “open data”, expectations of infrastructure functionalities, and barriers and enablers for the sharing of data. A wide range of good practice examples was pointed out by the respondents which demonstrates a substantial uptake of data sharing through e-infrastructures and a further need for enhancement and consolidation. Among all policy responses, funder policies seem to be the most important motivator. This supports the conclusion that stronger mandates will strengthen the case for data sharing. PMID:26771577

  15. Exposure to a maternal cafeteria diet changes open-field behaviour in the developing offspring.

    Science.gov (United States)

    Speight, Abigail; Davey, William G; McKenna, Emily; Voigt, Jörg-Peter W

    2017-04-01

    The early postnatal period is a sensitive period in rodents as behavioural systems are developing and maturing during this time. However, little is currently known about the behavioural effects of feeding a hyper-energetic cafeteria diet (CD) during the lactational period when offspring behaviour is tested during early adolescence. To this end, 23days old offspring from dams (Wistar) fed on CD during lactation were tested in either the open-field or the elevated plus-maze for exploration and anxiety-related behaviour. On postnatal day 9, maternal behaviour and non-maternal behaviour of the dam was assessed. It was hypothesized that lactational CD feeding would reduce anxiety in the offspring. CD-fed dams had a higher energy intake, due to an overconsumption of sugars and fats. When offspring from these dams were exposed to the open field after weaning, their locomotor activity was increased. They entered the more aversive inner zone of the open-field after a shorter latency, made more entries into and spent more time in the inner zone. Anxiety-related behaviour was not affected upon exposure to the elevated plus maze, suggesting anxiolysis in the open-field only. Increased maternal licking/grooming behaviour could possibly contribute to the anxiolytic phenotype as observed in the offspring from the CD group. In conclusion, we demonstrate that lactational overfeeding impacts on the development of behaviour in the early adolescent rat. Copyright © 2016 ISDN. Published by Elsevier Ltd. All rights reserved.

  16. Open NASA Earth Exchange (OpenNEX): A Public-Private Partnership for Climate Change Research

    Science.gov (United States)

    Nemani, R. R.; Lee, T. J.; Michaelis, A.; Ganguly, S.; Votava, P.

    2014-12-01

    NASA Earth Exchange (NEX) is a data, computing and knowledge collaborative that houses satellite, climate and ancillary data where a community of researchers can come together to share modeling and analysis codes, scientific results, knowledge and expertise on a centralized platform with access to large supercomputing resources. As a part of broadening the community beyond NASA-funded researchers, NASA through an agreement with Amazon Inc. made available to the public a large collection of Climate and Earth Sciences satellite data. The data, available through the Open NASA Earth Exchange (OpenNEX) platform hosted by Amazon Web Services (AWS) public cloud, consists of large amounts of global land surface imaging, vegetation conditions, climate observations and climate projections. In addition to the data, users of OpenNEX platform can also watch lectures from leading experts, learn basic access and use of the available data sets. In order to advance White House initiatives such as Open Data, Big Data and Climate Data and the Climate Action Plan, NASA over the past six months conducted the OpenNEX Challenge. The two-part challenge was designed to engage the public in creating innovative ways to use NASA data and address climate change impacts on economic growth, health and livelihood. Our intention was that the challenges allow citizen scientists to realize the value of NASA data assets and offers NASA new ideas on how to share and use that data. The first "ideation" challenge, closed on July 31st attracted over 450 participants consisting of climate scientists, hobbyists, citizen scientists, IT experts and App developers. Winning ideas from the first challenge will be incorporated into the second "builder" challenge currently targeted to launch mid-August and close by mid-November. The winner(s) will be formally announced at AGU in December of 2014. We will share our experiences and lessons learned over the past year from OpenNEX, a public-private partnership for

  17. Behavioral and Locomotor Measurements Using an Open Field Activity Monitoring System for Skeletal Muscle Diseases

    OpenAIRE

    Tatem, Kathleen S.; Quinn, James L.; Phadke, Aditi; Yu, Qing; Gordish-Dressman, Heather; Nagaraju, Kanneboyina

    2014-01-01

    The open field activity monitoring system comprehensively assesses locomotor and behavioral activity levels of mice. It is a useful tool for assessing locomotive impairment in animal models of neuromuscular disease and efficacy of therapeutic drugs that may improve locomotion and/or muscle function. The open field activity measurement provides a different measure than muscle strength, which is commonly assessed by grip strength measurements. It can also show how drugs may affect other body sy...

  18. Policy research institutions and the health SDGs: Open data ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    CEGSS, a Guatemalan think tank, will work with citizens' groups, health authorities, and policymakers to adapt and field-test a web-based citizen-led open data monitoring system for the implementation of SDG goals and targets related to health governance (primarily Goal 3 and Goal 16) in Guatemala. The web platform will ...

  19. On open and closed field line regions in Tsyganenko's field model and their possible associations with horse collar auroras

    International Nuclear Information System (INIS)

    Birn, J.; Hones, E.W. Jr.; Craven, J.D.; Frank, L.A.; Elphinstone, R.D.; Stern, D.P.

    1991-01-01

    Using the empirical Tsyganenko (1987) long model as a prime example of a megnetospheric field model, the authors have attempted to identify the boundary between open and closed field lines. They define as closed all field lines that are connested with the Earth at both ends and cross the equatorial plane earthward of x = -70 R E , the tailward validity limit of the Tsyganenko model. They find that the form of the open/closed boundary at the Earth's surface, identified with the polar cap boundary, can exhibit the arrowhead shape, pointed toward the Sun, observed in horse collar auroras (Hones et al., 1989). The polar cap size in the Tsyganenko model increases with increasing K p values, and it becomes rounder and less pointed. The superposition of a net B y field, which is the expected consequence of an IMF B y , rotates the polar cap pattern and, for larger values, degrades the arrowhead shape, resulting in polar cap configurations consistent with known asymmetries in the aurora. The pointedness of the polar cap shape also diminishes or even completely disappears if the low-latitude magnetopause is assumed open and located considerably inside of the outermost magnetic flux surface in the Tsyganenko model. The arrowhead shape of the polar cap is found to be associated with a strong increase of B z from midnight toward the tail flanks, which is observed independently, and is possibly related to the NBZ field-aligned current system, observed during quiet times and strongly northward IMF B z . The larger B z values near the flanks of the tail cause more magnetic flux to close through these regions than through the midnight equatorial region

  20. Influence of fogging lenses and cycloplegia on open-field automatic refraction.

    Science.gov (United States)

    Queirós, A; González-Méijome, J; Jorge, J

    2008-07-01

    To compare refractive values measured with and without cycloplegia, or with fogging lenses, using an open-field auto-refractor. One hundred and forty-two young adults were enrolled from a university population; 96 were female (67.6%) and 46 were male (32.4%), the age range was 18-26 years (mean 22.3 +/- 3.7 years). The refraction measurement was obtained for the right eye of each subject with the Grand Seiko Auto Ref/Keratometer WAM-5500 (GS) under three conditions, always in this sequence: (1) without cycloplegia (GS), (2) without cycloplegia but using a + 2.00 D fogging lens (GS_2D) and (3) with cycloplegia (GS_cycl). When the average values of spherical equivalent were compared, both accommodation control strategies were almost equally successful: GS, M = -0.85 +/- 2.21 D; GC_2D, M = -0.53 +/- 2.10 D and GS_cycl, M = -0.57 +/- 2.24 D (Kruskal-Wallis test, p open-field autorefraction is performed in young adults.

  1. Field Research Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Field Research Facility (FRF) located in Duck, N.C. was established in 1977 to support the U.S. Army Corps of Engineers' coastal engineering mission. The FRF is...

  2. Coalition works to secure open access to published research

    CERN Multimedia

    Brown, Susan

    2006-01-01

    "Paying upfront: a group of particle physicists has proposed a new way to pay for immediate free access to journal articles in their field. They want to raise five million to six million euros (about US $7-million) a year to buy open access to peer-reviewed papers in top physics journals. (2 pages)

  3. Effect of interleukin-1beta on the behavior of rats during mild stress in the open-field test.

    Science.gov (United States)

    Pertsov, S S; Koplik, E V; Simbirtsev, A S; Kalinichenko, L S

    2009-11-01

    We studied the effect of interleukin-1beta on the behavior of rats with different individual typological characteristics during mild stress in the open-field test. Intraperitoneal injection of interleukin-1beta (5 microg/kg, 108 U/mg) was followed by a decrease in orientation and exploratory activity of passive and, particularly, of active animals in the open field. As differentiated from rats receiving physiological saline, the initial differences in behavioral characteristics of active and passive animals were not revealed in the repeated test after injection of interleukin-1beta. We conclude that interleukin-1beta abolishes the behavioral differences between active and passive specimens in the open field. These data suggest that administration of interleukin-1beta to rats leads to reorganization of the mechanisms for emotional evaluation of adverse emotiogenic factors under conditions of mild stress in the open-field test.

  4. Strain Differences of Mice for Open Field Behaviour, Circadian Rhythms,and Morphine Reactivity

    OpenAIRE

    Sekiguchi, Shigehisa

    1982-01-01

    This paper deals with some of the work in the field of Behaviour Genetics at the Psychological Laboratory in Shiga University. The first part concerns open field behaviour, the second part discusses circadian rhythms of general activity and of sleepwakefulness cycle, and the third part relates to morphine effects on avoidance behaviour.

  5. Precipitation-generated oscillations in open cellular cloud fields.

    Science.gov (United States)

    Feingold, Graham; Koren, Ilan; Wang, Hailong; Xue, Huiwen; Brewer, Wm Alan

    2010-08-12

    Cloud fields adopt many different patterns that can have a profound effect on the amount of sunlight reflected back to space, with important implications for the Earth's climate. These cloud patterns can be observed in satellite images of the Earth and often exhibit distinct cell-like structures associated with organized convection at scales of tens of kilometres. Recent evidence has shown that atmospheric aerosol particles-through their influence on precipitation formation-help to determine whether cloud fields take on closed (more reflective) or open (less reflective) cellular patterns. The physical mechanisms controlling the formation and evolution of these cells, however, are still poorly understood, limiting our ability to simulate realistically the effects of clouds on global reflectance. Here we use satellite imagery and numerical models to show how precipitating clouds produce an open cellular cloud pattern that oscillates between different, weakly stable states. The oscillations are a result of precipitation causing downward motion and outflow from clouds that were previously positively buoyant. The evaporating precipitation drives air down to the Earth's surface, where it diverges and collides with the outflows of neighbouring precipitating cells. These colliding outflows form surface convergence zones and new cloud formation. In turn, the newly formed clouds produce precipitation and new colliding outflow patterns that are displaced from the previous ones. As successive cycles of this kind unfold, convergence zones alternate with divergence zones and new cloud patterns emerge to replace old ones. The result is an oscillating, self-organized system with a characteristic cell size and precipitation frequency.

  6. A method for opening a mine field which is adjacent to a pit

    Energy Technology Data Exchange (ETDEWEB)

    Onishchenko, V.I.; Grebenyuk, V.K.; Kukharev, V.N.; Martynenko, V.P.; Omelnitskiy, A.G.; Sallin, V.I.; Sidorov, A.S.

    1982-01-01

    The method for opening a mine field adjacent to a pit includes the construction of the main and auxiliary opening drifts in the pit and the surface complex of the mine through assembling a support with subsequent filling of them by tailings of the covering rock. In order to increase the productive capacity of the mine, to reduce capital expenditures and to increase the safety of underground operations, a base is first formed from the tailing rock along the front of the open mining operations, from the bottom of the pit at the level of the stratum being opened to the surface with simultaneous layer by layer packing of the cited base, after which the opening drifts are built on this base. The mouth of the main opening drifts and the surface complex of the mine are positioned in the region of the pit.

  7. Share your dream. Towards a new model for open collaborative research in Europe

    NARCIS (Netherlands)

    Becklert, B.; Friedewald, M.; Schaper-Rinkel, P.; Weber, M.; Lieshout, M.J. van; Giessen, A.M. van der; Leis, M.J.S.

    2012-01-01

    The study “Boosting the exploratory power of Open Research in Future and Emerging Technologies (FET)” is designed to support the activities of the European Commission to strengthen Open Collaborative Research and to establish it as a new mode of funding and doing research in Europe. It describes the

  8. Creating Open Education Resources for Teaching and Community Development through Action Research: An Overview of the Makerere AgShare Project

    Science.gov (United States)

    Kaneene, John B.; Ssajjakambwe, Paul; Kisaka, Stevens; Miller, RoseAnn; Kabasa, John D.

    2013-01-01

    The AgShare Phase I Program, conducted at Makerere University, Kampala, Uganda, was formed to create open education resources for teaching and community development through action research. The study was conducted by an interdisciplinary team of investigators from fields of veterinary medicine and agri-business. Two master of science students…

  9. Environmental novelty and illumination modify ethanol-induced open-field behavioral effects in mice.

    Science.gov (United States)

    Fukushiro, Daniela F; Benetti, Liliane F; Josino, Fabiana S; Oliveira, Gabriela P; Fernandes, Maiara deM; Saito, Luis P; Uehara, Regina A; Wuo-Silva, Raphael; Oliveira, Camila S; Frussa-Filho, Roberto

    2010-03-01

    Both spontaneous and drug-induced animal behaviors can be modified by exposure to novel stimuli or different levels of environmental illumination. However, research into how these factors specifically impact ethanol (ETH)-induced behavioral effects is currently lacking. We aimed to investigate the effects of these two factors, considered separately or in conjunction, on ETH-induced acute hyperlocomotor effect and its sensitization in adult male Swiss mice. Mice were placed in a novel or familiar open-field under normal light (200 lx) or low light (9 lx) immediately after receiving an ip injection of either 1.8 g/kg ETH or saline (SAL). After 7 days, all animals received an ip challenge injection of 1.8 g/kg ETH, and were placed in the open-field under the same light conditions described above. Novelty increased central locomotion and decreased grooming, while low light increased grooming. Acute ETH administration increased both total and peripheral locomotion and these effects were potentiated by low light. Both low light and novelty were able to facilitate ETH-induced locomotor sensitization, which was detected by the central locomotion parameter. However, there was no synergism between the effects of these two modulating factors on ETH-induced behavioral sensitization. We conclude that both the acute behavioral effects of ETH and behavioral sensitization induced by previous administration of this drug can be critically modified by environmental factors. In addition, our study stresses the importance of using different behavioral parameters to evaluate the interaction between environmental factors and ETH effects. (c) 2009 Elsevier Inc. All rights reserved.

  10. Gender-related response in open-field activity following developmental nicotine exposure in rats.

    Science.gov (United States)

    Romero, Roland D; Chen, Wei-Jung A

    2004-08-01

    Smoking during pregnancy may lead to low birthweight and behavioral alterations in the offspring. In this study, the effects of developmental nicotine exposure on the somatic growth of the offspring and the behavioral performance in the open-field test were examined. Sprague-Dawley female rats were implanted with nicotine (35 mg for 21-day time release; NIC 35) or placebo pellets on gestational day (GD) 8 (postblastocyst implantation). A normal control group with no pellet implant was also included. There was a significantly higher maternal weight gain in the placebo group possibly due to a larger litter size. However, there were no significant differences in body weights among all three treatment groups for male and female offspring. The amount of activity, measured by the total number of crossings in the open-field test, indicated a gender difference in baseline level and pattern of ambulatory activity, with less activity (lower number of crossings) in male offspring and an increase in the activity of the female offspring as a function of testing day. The increase in the ambulatory activity of the female offspring was observed in the placebo and normal, but not the NIC 35 group suggesting that developmental nicotine exposure interferes with open-field activity, and this behavioral alteration is gender related. Copyright 2004 Elsevier Inc.

  11. Crossfostering in mice selectively bred for high and low levels of open-field thigmotaxis.

    Science.gov (United States)

    Leppänen, Pia K; Ewalds-Kvist, S Béatrice M

    2005-02-01

    The main purpose of this research was to investigate whether the difference in open-field (OF) thigmotaxis between mice selectively bred for high and low levels of wall-seeking behavior originated from genetic or acquired sources. Unfostered, infostered, and crossfostered mice were compared in two experiments in which the effects of strain, sex, and fostering on ambulation, defecation, exploration, grooming, latency to move, radial latency, rearing, thigmotaxis, and urination were studied. These experiments revealed that OF thigmotaxis was unaffected by the foster condition and thus genetically determined. The selected strains of mice also diverged repeatedly with regard to exploration and rearing. The findings are in line with the previously described existence of an inverse relationship between emotionality and exploration.

  12. Open source drug discovery--a new paradigm of collaborative research in tuberculosis drug development.

    Science.gov (United States)

    Bhardwaj, Anshu; Scaria, Vinod; Raghava, Gajendra Pal Singh; Lynn, Andrew Michael; Chandra, Nagasuma; Banerjee, Sulagna; Raghunandanan, Muthukurussi V; Pandey, Vikas; Taneja, Bhupesh; Yadav, Jyoti; Dash, Debasis; Bhattacharya, Jaijit; Misra, Amit; Kumar, Anil; Ramachandran, Srinivasan; Thomas, Zakir; Brahmachari, Samir K

    2011-09-01

    It is being realized that the traditional closed-door and market driven approaches for drug discovery may not be the best suited model for the diseases of the developing world such as tuberculosis and malaria, because most patients suffering from these diseases have poor paying capacity. To ensure that new drugs are created for patients suffering from these diseases, it is necessary to formulate an alternate paradigm of drug discovery process. The current model constrained by limitations for collaboration and for sharing of resources with confidentiality hampers the opportunities for bringing expertise from diverse fields. These limitations hinder the possibilities of lowering the cost of drug discovery. The Open Source Drug Discovery project initiated by Council of Scientific and Industrial Research, India has adopted an open source model to power wide participation across geographical borders. Open Source Drug Discovery emphasizes integrative science through collaboration, open-sharing, taking up multi-faceted approaches and accruing benefits from advances on different fronts of new drug discovery. Because the open source model is based on community participation, it has the potential to self-sustain continuous development by generating a storehouse of alternatives towards continued pursuit for new drug discovery. Since the inventions are community generated, the new chemical entities developed by Open Source Drug Discovery will be taken up for clinical trial in a non-exclusive manner by participation of multiple companies with majority funding from Open Source Drug Discovery. This will ensure availability of drugs through a lower cost community driven drug discovery process for diseases afflicting people with poor paying capacity. Hopefully what LINUX the World Wide Web have done for the information technology, Open Source Drug Discovery will do for drug discovery. Copyright © 2011 Elsevier Ltd. All rights reserved.

  13. Behavior in the open field predicts the number of KCl-induced cortical spreading depressions in rats.

    Science.gov (United States)

    Bogdanov, Volodymyr Borysovych; Bogdanova, Olena Viktorivna; Koulchitsky, Stanislav Vladimirovich; Chauvel, Virginie; Multon, Sylvie; Makarchuk, Mykola Yukhymovych; Brennan, Kevin Christopher; Renshaw, Perry Franklin; Schoenen, Jean

    2013-01-01

    Anxiety disorders are known to be comorbid with migraine, and cortical spreading depression (CSD) is the most likely cause of the migraine aura. To search for possible correlations between susceptibility to CSD and anxiety we used the open field test in male Sprague-Dawley rats chronically treated with the preventive anti-migraine drugs valproate or riboflavin. Animals avoiding the central area of the open field chamber and those with less exploratory activity (i.e. rearing) were considered more anxious. After 4 weeks of treatment CSDs were elicited by application of 1M KCl over the occipital cortex and the number of CSDs occurring over a 2h period was compared to the previously assessed open field behavior. Higher anxiety-like behavior was significantly correlated with a higher frequency of KCl-induced CSDs. In saline-treated animals, fewer rearings were found in animals with more frequent CSDs (R=-1.00). The duration of ambulatory episodes in the open field center correlated negatively with number of CSDs in the valproate group (R=-0.83; popen field center in both groups (R=-0.75; p<0.05 and R=-0.58; p<0.1 respectively). These results suggest that anxiety symptoms are associated with susceptibility to CSD and might explain why it can be an aggravating factor in migraine with aura. Copyright © 2012 Elsevier B.V. All rights reserved.

  14. Radiation breeding researches in gamma field. Results of researches

    International Nuclear Information System (INIS)

    Morishita, Toshikazu

    2006-01-01

    Abstract of radiation breeding researches and outline of gamma field in IRB (Institute of Radiation Breeding) are described. The gamma field is a circular field of 100 m radius with 88.8TBqCo-60 source at the center. The field is surrounded by a shielding dike of 8 m in height. The effects of gamma irradiation on the growing plants, mutant by gamma radiation and plant molecular biological researches using mutant varieties obtained by the gamma field are explained. For examples, Japanese pear, chrysanthemum, Cytisus, Eustoma grandiflorum, Manila grass, tea and rose are reported. The mutant varieties in the gamma field, nine mutant varieties of flower colors in chrysanthemum, evergreen mutant lines in Manila grass, selection of self-compatible mutants in tea plant, and the plants of the gamma field recently are shown. (S.Y.)

  15. Practices in NASA's EOSDIS to Promote Open Data and Research Integrity

    Science.gov (United States)

    Behnke, J.; Ramapriyan, H.

    2017-12-01

    The purpose of this paper is to highlight the key practices adopted by NASA in its Earth Observing System Data and Information System (EOSDIS) to promote and facilitate open data and research integrity. EOSDIS is the system that manages most of NASA's Earth science data from various sources - satellites, aircraft, field campaigns and some research projects. Since its inception in 1990 as a part of the Earth Observing System (EOS) Program, EOSDIS has been following NASA's free and open data and information policy, whereby data are shared with all users on a non-discriminatory basis and are provided at no cost. To ensure that the data are discoverable and accessible to the user community, NASA follows an evolutionary development approach, whereby the latest technologies that can be practically adopted are infused into EOSDIS. This results in continuous improvements in system capabilities such that technologies that users are accustomed to in other environments are brought to bear in their access to NASA's Earth observation data. Mechanisms have existed for ensuring that the data products offered by EOSDIS are vetted by the community before they are released. Information about data products such as Algorithm Theoretical Basis Documents and quality assessments are openly available with the products. The EOSDIS Distributed Active Archive Centers (DAACs) work with the science teams responsible for product generation to assist with proper use of metadata. The DAACs have knowledgeable staff to answer users' questions and have access to scientific experts as needed. Citation of data products in scientific papers are facilitated by assignment of Digital Object Identifiers (DOIs) - at present, over 50% of data products in EOSDIS have been assigned DOIs. NASA gathers and publishes citation metrics for the datasets offered by the DAACs. Through its Software and Services Citations Working Group, NASA is currently investigating broadening DOI assignments to promote greater

  16. Research into Open Educational Resources for Development | CRDI ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Among them is the growing demand for postsecondary education when most ... thanks in part to greater access to the Internet and new flexible intellectual property licenses. ... While OERs are receiving considerable attention in universities, education ... develop researchers' capacity to analyze open educational resources; ...

  17. Mice selectively bred for open-field thigmotaxis: life span and stability of the selection trait.

    Science.gov (United States)

    Leppänen, Pia K; Ewalds-Kvist, S Béatrice M; Selander, Ritva-Kajsa

    2005-04-01

    In 2 experiments, the authors examined 69 mice selectively bred for high or low levels of open-field (OF) thigmotactic behavior (high open-field thigmotaxis [HOFT] and low open-field thigmotaxis [LOFT], respectively). They found that the strains differed in defecation during the 60-min exposure to the OF. Furthermore, the strains differed with regard to their life spans: The more thigmotactic HOFT mice lived longer than the LOFT mice. The strains were not differentiated by food intake or excretion. The strain difference in thigmotaxis was not age dependent, and it persisted in the home-cage condition as well. Neither the location (center or wall) of the starting point nor the shape (circular or square) of the OF arena affected the difference in wall-seeking behavior between the two strains. The authors concluded that the difference in thigmotaxis (or emotionality) between the HOFT and LOFT mice is a stable and robust feature of these animals.

  18. African Innovation Research on Intellectual Property's Role in Open ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    African Innovation Research on Intellectual Property's Role in Open Development ... thereby promoting globally competitive African industries and services. ... Furthermore, the measurement of innovation and knowledge production is based on ...

  19. Near-Field Acoustic Power Level Analysis of F31/A31 Open Rotor Model at Simulated Cruise Conditions, Technical Report II

    Science.gov (United States)

    Sree, Dave

    2015-01-01

    Near-field acoustic power level analysis of F31A31 open rotor model has been performed to determine its noise characteristics at simulated cruise flight conditions. The non-proprietary parts of the test data obtained from experiments in the 8x6 supersonic wind tunnel were provided by NASA-Glenn Research Center. The tone and broadband components of total noise have been separated from raw test data by using a new data analysis tool. Results in terms of sound pressure levels, acoustic power levels, and their variations with rotor speed, freestream Mach number, and input shaft power, with different blade-pitch setting angles at simulated cruise flight conditions, are presented and discussed. Empirical equations relating models acoustic power level and input shaft power have been developed. The near-field acoustic efficiency of the model at simulated cruise conditions is also determined. It is hoped that the results presented in this work will serve as a database for comparison and improvement of other open rotor blade designs and also for validating open rotor noise prediction codes.

  20. How to create successful Open Hardware projects — About White Rabbits and open fields

    International Nuclear Information System (INIS)

    Bij, E van der; Arruat, M; Cattin, M; Daniluk, G; Cobas, J D Gonzalez; Gousiou, E; Lewis, J; Lipinski, M M; Serrano, J; Stana, T; Voumard, N; Wlostowski, T

    2013-01-01

    CERN's accelerator control group has embraced ''Open Hardware'' (OH) to facilitate peer review, avoid vendor lock-in and make support tasks scalable. A web-based tool for easing collaborative work was set up and the CERN OH Licence was created. New ADC, TDC, fine delay and carrier cards based on VITA and PCI-SIG standards were designed and drivers for Linux were written. Often industry was paid for developments, while quality and documentation was controlled by CERN. An innovative timing network was also developed with the OH paradigm. Industry now sells and supports these designs that find their way into new fields

  1. A Measurement and Analysis of Buildup Region Dose for Open Field Photon Beams (Cobalt-60 through 24 MV)

    International Nuclear Information System (INIS)

    McCullough, Edwin C.

    2015-01-01

    The central axis depth dose in the build-up region (surface to d_m_a_x) of single open field photon beams (cobalt-60 through 24 MV) has been measured utilizing parallel plate and extrapolation chamber methodology. These data were used to derive, for a prescription dose of 100 cGy, values of surface dose, the maximum value of dose along the central axis (D_m_a_x) and the depth (nearest the surface) at which 90% of the prescription dose occurs (d_9_0). For both single and parallel opposed pair (POP) open field configurations, data are presented at field sizes of 5 × 5, 15 × 15 and 25 × 25 cm"2 for prescription depths of 10, 15 and 20 cm (midplane for POP). For the treatment machines, field sizes, and prescription depths studied, it is possible to conclude that: for single open field irradiation, surface dose values (as a percentage of the prescription dose) can be either low (<10%) or comparable to the prescription dose itself; for POP open fields, surface dose values are relatively independent of photon energy and midplane depth, and range between 30% and 70% of prescription dose, being principally dependent on field size; the depth of the initial 90 cGy point for a prescription dose of 100 cGy, d_9_0, was larger for POP fields. For either single or POP open field treatments, d_9_0 was always less than 22 mm, while for 6 MV or less, values of d_9_0 were less than 4 mm; D_m_a_x values can be very large (e.g., above 300 cGy) for certain treatment situations and are reduced significantly for POP treatments; for open field POP treatments, the percent reduction in D_m_a_x with each increment in beam energy above 10 MV is reduced over that seen at 10 MV or less and, possibly, this further reduction may be clinically insignificant; for open field POP treatments, changes in surface dose, d_9_0 and D_m_a_x with beam energy above 10 MV do not suggest, with regard to these specific build-up curve parameters, any obvious advantage for treatment with beam energies greater

  2. Field research opens new vistas in Vietnam | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Her research on understanding non-farm employment among ethnic minority groups threw Le Barbenchon's work a few initial curves. First, her permits were delayed, forcing her to consider different work. Then she discovered that national surveys had not properly captured migration of ethnic minorities and to find enough ...

  3. Widening Access through Openness in Higher Education in the Developing World: A Bourdieusian Field Analysis of Experiences from the National Open University of Nigeria

    Science.gov (United States)

    Olakulehin, Felix Kayode; Singh, Gurmit

    2013-01-01

    Bourdieu has argued that higher education is a field that reproduces social inequality, thus complicating how openness widens access to higher education in the developing world. Drawing on the experiences of the National Open University of Nigeria (NOUN), this paper critically analyses and evaluates the rationale, approach, difficulties,…

  4. Reducing the ecological impact of field research.

    Science.gov (United States)

    Bezanson, Michelle; Stowe, Rochelle; Watts, Sean M

    2013-01-01

    Researchers and students at biological field stations, especially in remote areas, are subject to leaving "footprints," as we conduct research, work, and live in sensitive ecosystems. These footprints include travel, personal trash and waste, and field equipment (e.g. flagging, tree markers, plot markers, trail markers, monitoring devices, etc.). In this commentary, we argue that the field of primatology's commitment to minimum impact research should be more explicitly and visibly integrated into our ethical protocols with regard to field research and instruction in sensitive environments. We review current ethical codes and potential solutions to reducing our "researcher footprints" while conducting fieldwork. Using Costa Rica as an example, we address how sustainable fieldwork differs among varying cultural contexts and argue that researchers should be made responsible and accountable for how our presence, research, and teaching might impact the environment. We conclude by recommending a set of guidelines to be added to ethical protocols regarding research design, station policies, and the conduct of research and teaching in the field. © 2012 Wiley Periodicals, Inc.

  5. Low-latitude boundary layer near noon: An open field line model

    Science.gov (United States)

    Lyons, L. R.; Schulz, M.; Pridmore-Brown, D. C.; Roeder, J. L.

    1994-01-01

    We propose that many features of the cusp and low-latitude boundary layer (LLBL) observed near noon MLT can be explained by interpreting the LLBL as being on open lines with an inner boundary at the separatrix between open and closed magnetic field lines. This interpretation places the poleward boundary of the LLBL and equatorward boundary of the cusp along the field line that bifurcates at the cusp neutral point. The interpretation accounts for the abrupt boundary of magnetosheath particles at the inner edge of the LLBL, a feature that is inconsistent with LLBL formation by diffusion onto closed field lines, and for the distribution of magnetosheath particles appearing more as one continuous region than as two distinct regions across the noon cusp/LLBL boundary. Furthermore, we can explain the existence of energetic radiation belt electrons and protons with differing pitch angle distributions within the LLBL and their abrupt cutoff at the poleward boundary of the LLBL. By modeling the LLBL and cusp region quantitatively, we can account for a hemispherical difference in the location of the equatorial boundary of the cusp that is observed to be dependent on the dipole tilt angle but not on the interplanetary magnetic field (IMF) x component. We also find important variations and hemispherical differences in that the size of the LLBL that should depend strongly upon the x component of the IMF. This prediction is observationally testable. Finally, we find that when the IMF is strongly northward, the LLBL may include a narrow region adjacent to the magnetopause where field lines are detached (i.e., have both ends connected to the IMF).

  6. Open Access Data Sharing in Genomic Research

    Directory of Open Access Journals (Sweden)

    Stacey Pereira

    2014-08-01

    Full Text Available The current emphasis on broad sharing of human genomic data generated in research in order to maximize utility and public benefit is a significant legacy of the Human Genome Project. Concerns about privacy and discrimination have led to policy responses that restrict access to genomic data as the means for protecting research participants. Our research and experience show, however, that a considerable number of research participants agree to open access sharing of their genomic data when given the choice. General policies that limit access to all genomic data fail to respect the autonomy of these participants and, at the same time, unnecessarily limit the utility of the data. We advocate instead a more balanced approach that allows for individual choice and encourages informed decision making, while protecting against the misuse of genomic data through enhanced legislation.

  7. LIS Practitioner-focused Research Trends Toward Open Access Journals, Academic-focused Research Toward Traditional Journals

    Directory of Open Access Journals (Sweden)

    Richard Hayman

    2018-03-01

    Full Text Available A Review of: Chang, Y-W. (2017. Comparative study of characteristics of authors between open access and non-open access journals in library and information science. Library & Information Science Research, 39(1, 8-15. http://dx.doi.org/10.1016/j.lisr.2017.01.002   Abstract  Objective – To examine the occupational characteristics and publication habits of library and information science (LIS authors regarding traditional journals and open access journals. Design – Content analysis. Setting – English language research articles published in open access (OA journals and non-open access (non-OA journals from 2008 to 2013 that are indexed in LIS databases. Subjects – The authorship characteristics for 3,472 peer-reviewed articles. Methods – This researcher identified 33 total journals meeting the inclusion criteria by using the LIS categories within 2012 Journal Citation Reports (JCR to find 13 appropriate non-OA journals, and within the Directory of Open Access Journals (DOAJ to identify 20 appropriate OA journals. They found 1,665 articles by 3,186 authors published in the non-OA journals, and another 1,807 articles by 3,446 authors within the OA journals. The researcher used author affiliation to determine article authors’ occupations using information included in the articles themselves or by looking for information on the Internet, and excluded articles when occupational information could not be located. Authors were categorized into four occupational categories: Librarians (practitioners, Academics (faculty and researchers, Students (graduate or undergraduate, and Others. Using these categories, the author identified 10 different types of collaborations for co-authored articles. Main Results – This research involves three primary research questions. The first examined the occupational differences between authors publishing in OA journals versus non-OA journals. Academics (faculty and researchers more commonly published in non

  8. Automated TV based system for open field studies: Effects of methamphetamine

    NARCIS (Netherlands)

    Tanger, H.J.; Vanwersch, R.A.P.; Wolthuis, O.L.

    1978-01-01

    A method is described whereby open field behaviour of rats can be automatically registered using a TV camera, a video converter, an X-Y recorder and a papertape puncher. Use is made of the scanning properties of the TV camera to obtain the X and Y coordinates of the rat's position and to print this

  9. Prepartum and postpartum open-field behavior and maternal responsiveness in mice bidirectionally selected for open-field thigmotaxis.

    Science.gov (United States)

    Leppänen, Pia K; Ravaja, Niklas; Ewalds-Kvist, S Béatrice M

    2008-01-01

    The authors examined pre- and postpartum open-field (OF) behavior and maternal responsiveness in mice that they bidirectionally selected for OF thigmotaxis. The authors tested 40 female mice under 3 conditions: prepartum OF, postpartum OF, and a pup retrieval test. In both OF conditions, the high OF thigmotaxis (HOFT) mice were more thigmotactic but explored and reared less than the low OF thigmotaxis (LOFT) mice, indicating that the HOFT mice were more emotional. In the postpartum condition, the HOFT mothers also defecated more and ambulated less than the LOFT mothers. The increase in grooming after parturition was more conspicuous among the LOFT mothers than among the HOFT mothers. The LOFT mothers were also more attracted to their pups in the OF, but the retrieval test did not show any substantial line differences. The results suggested that the line difference in emotionality was more pronounced during lactation than during pregnancy, although parturition exerted no effect on thigmotaxis.

  10. Comparison between visual field defect in pigmentary glaucoma and primary open-angle glaucoma.

    Science.gov (United States)

    Nilforushan, Naveed; Yadgari, Maryam; Jazayeri, Anisalsadat

    2016-10-01

    To compare visual field defect patterns between pigmentary glaucoma and primary open-angle glaucoma. Retrospective, comparative study. Patients with diagnosis of primary open-angle glaucoma (POAG) and pigmentary glaucoma (PG) in mild to moderate stages were enrolled in this study. Each of the 52 point locations in total and pattern deviation plot (excluding 2 points adjacent to blind spot) of 24-2 Humphrey visual field as well as six predetermined sectors were compared using SPSS software version 20. Comparisons between 2 groups were performed with the Student t test for continuous variables and the Chi-square test for categorical variables. Thirty-eight eyes of 24 patients with a mean age of 66.26 ± 11 years (range 48-81 years) in the POAG group and 36 eyes of 22 patients with a mean age of 50.52 ± 11 years (range 36-69 years) in the PG group were studied. (P = 0.00). More deviation was detected in points 1, 3, 4, and 32 in total deviation (P = 0.03, P = 0.015, P = 0.018, P = 0.023) and in points 3, 4, and 32 in pattern deviation (P = 0.015, P = 0.049, P = 0.030) in the POAG group, which are the temporal parts of the field. It seems that the temporal area of the visual field in primary open-angle glaucoma is more susceptible to damage in comparison with pigmentary glaucoma.

  11. OpenSIGLE - Crossroads for Libraries, Research and Educational Institutions in the field of Grey Literature

    OpenAIRE

    Farace, Dominic J. (GreyNet); Frantzen, Jerry (GreyNet); Stock, Christiane (INIST-CNRS); Henrot, Nathalie (INIST-CNRS); Schöpfel, Joachim (University of Lille); GreyNet, Grey Literature Network Service

    2009-01-01

    This poster is based on a paper presented at the Tenth International Conference on Grey Literature (GL10) in which GreyNet's collections of conference preprints were made accessible via the OpenSIGLE Repository. OpenSIGLE offers a unique distribution channel for European grey literature with roots dating back a quarter century. The experience of INIST as service provider and GreyNet as data provider will be further discussed including recent developments. The poster closes...

  12. Identifying a cooperative control mechanism between an applied field and the environment of open quantum systems

    Science.gov (United States)

    Gao, Fang; Rey-de-Castro, Roberto; Wang, Yaoxiong; Rabitz, Herschel; Shuang, Feng

    2016-05-01

    Many systems under control with an applied field also interact with the surrounding environment. Understanding the control mechanisms has remained a challenge, especially the role played by the interaction between the field and the environment. In order to address this need, here we expand the scope of the Hamiltonian-encoding and observable-decoding (HE-OD) technique. HE-OD was originally introduced as a theoretical and experimental tool for revealing the mechanism induced by control fields in closed quantum systems. The results of open-system HE-OD analysis presented here provide quantitative mechanistic insights into the roles played by a Markovian environment. Two model open quantum systems are considered for illustration. In these systems, transitions are induced by either an applied field linked to a dipole operator or Lindblad operators coupled to the system. For modest control yields, the HE-OD results clearly show distinct cooperation between the dynamics induced by the optimal field and the environment. Although the HE-OD methodology introduced here is considered in simulations, it has an analogous direct experimental formulation, which we suggest may be applied to open systems in the laboratory to reveal mechanistic insights.

  13. USING THE INTERNATIONAL SCIENTOMETRIC DATABASES OF OPEN ACCESS IN SCIENTIFIC RESEARCH

    Directory of Open Access Journals (Sweden)

    O. Galchevska

    2015-05-01

    Full Text Available In the article the problem of the use of international scientometric databases in research activities as web-oriented resources and services that are the means of publication and dissemination of research results is considered. Selection criteria of scientometric platforms of open access in conducting scientific researches (coverage Ukrainian scientific periodicals and publications, data accuracy, general characteristics of international scientometrics database, technical, functional characteristics and their indexes are emphasized. The review of the most popular scientometric databases of open access Google Scholar, Russian Scientific Citation Index (RSCI, Scholarometer, Index Copernicus (IC, Microsoft Academic Search is made. Advantages of usage of International Scientometrics database Google Scholar in conducting scientific researches and prospects of research that are in the separation of cloud information and analytical services of the system are determined.

  14. Comparative energy input–output and financial analyses of greenhouse and open field vegetables production in West Java, Indonesia

    International Nuclear Information System (INIS)

    Kuswardhani, Nita; Soni, Peeyush; Shivakoti, Ganesh P.

    2013-01-01

    This paper estimates energy consumption per unit floor area of greenhouse and open field for tomato, chili and lettuce production. Primary data were collected from 530 vegetable farmers during Jan–Dec, 2010 in West Java, Indonesia. Energy estimates were calculated from actual amount of inputs and outputs and corresponding conversion factors. Results reveal that the total input energy used in greenhouse (GH) production of tomato, chili (medium and high land) and lettuce were 47.62, 41.55, 58.84, and 24.54 GJ/ha respectively. Whereas, the requirement of total input energy for open field (OF) production of tomato, chili (medium and high land) and lettuce were 49.01, 41.04, 57.94 and 23.87 GJ/ha, respectively. The ratio of output to input energy was higher in greenhouse production (0.85, 0.45 and 0.49) than open field vegetable production (0.52, 0.175 and 0.186) for tomato, chili medium land and chili highland, respectively, but output–input ratio of lettuce open field production was twice as that of greenhouse vegetable production. Financial analysis revealed higher mean net returns from greenhouse vegetable production as 7043 $/ha (922–15,299 $/ha) when compared to 571 $/ha (44–1172 $/ha) from open field vegetable production. Among the greenhouse vegetables, tomato cultivation was the most profitable in terms of energy efficiency and financial productivity. - Highlights: ► Energy input–output analysis is carried out to compare vegetables production in greenhouse and open field. ► Tomato, Chili and Lettuce production in West Java, Indonesia. ► Economic analysis is conducted to compare the two production systems

  15. The Value of Open Source Software Tools in Qualitative Research

    Science.gov (United States)

    Greenberg, Gary

    2011-01-01

    In an era of global networks, researchers using qualitative methods must consider the impact of any software they use on the sharing of data and findings. In this essay, I identify researchers' main areas of concern regarding the use of qualitative software packages for research. I then examine how open source software tools, wherein the publisher…

  16. Access and preservation of digital research content: Linked open data services - A research library perspective

    Science.gov (United States)

    Kraft, Angelina; Sens, Irina; Löwe, Peter; Dreyer, Britta

    2016-04-01

    Globally resolvable, persistent digital identifiers have become an essential tool to enable unambiguous links between published research results and their underlying digital resources. In addition, this unambiguous identification allows citation. In an ideal research world, any scientific content should be citable and the coherent content, as well as the citation itself, should be persistent. However, today's scientists do not just produce traditional research papers - they produce comprehensive digital collections of objects which, alongside digital texts, include digital resources such as research data, audiovisual media, digital lab journals, images, statistics and software code. Researchers start to look for services which allow management of these digital resources with minimum time investment. In light of this, we show how the German National Library of Science and Technology (TIB) develops supportive frameworks to accompany the life cycle of scientific knowledge generation and transfer. This includes technical infrastructures for • indexing, cataloguing, digital preservation, DOI names and licencing for text and digital objects (the TIB DOI registration, active since 2004) and • a digital repository for the deposition and provision of accessible, traceable and citeable research data (RADAR). One particular problem for the management of data originating from (collaborating) research infrastructures is their dynamic nature in terms of growth, access rights and quality. On a global scale, systems for access and preservation are in place for the big data domains (e.g. environmental sciences, space, climate). However, the stewardship for disciplines without a tradition of data sharing, including the fields of the so-called long tail, remains uncertain. The RADAR - Research Data Repository - project establishes a generic end-point data repository, which can be used in a collaborative way. RADAR enables clients to upload, edit, structure and describe their

  17. Field theory of interacting open superstrings of fermionic ghost representation

    International Nuclear Information System (INIS)

    Aref'eva, I.Ya.; Medvedev, P.V.

    1987-01-01

    Field theory of interacting open superstring in fermionic ghost representation based on anticommuting and commuting ghosts corresponding respectively to world sheet bosonic x μ and fermionic φ μ coordinates is presented. The author have to revise once more the field theory of the free Ramond (R) string and starting from general algebraic point of view they obtain that the number of degrees of freedom in the R and NS (Neveu-Schwartz) sectors equalise themselves permitting to construct a supersymmetric operator. It is proposed to solve a specific equation guaranteeing superinvariance in order to find the R-R-NS and NS-R-R vertices in the term of the NS-NS-NS vertex

  18. Ethical considerations for field research on fishes

    Directory of Open Access Journals (Sweden)

    Rhett H. Bennett

    2016-12-01

    Full Text Available Collection of data from animals for research purposes can negatively impact target or by-catch species if suitable animal ethics practices are not followed. This study aimed to assess the ethical requirements of peer-reviewed scientific journals that publish primary literature on fishes, and review the ethical considerations and animal care guidelines of national and international documents on the ethical treatment of animals for research, to provide an overview of the general ethical considerations for field research on fishes. A review of 250 peer-reviewed, ISI-rated journals publishing primary research on fishes revealed that nearly half (46% had no mention of ethics, treatment of animals or ethical requirements for publication in their author guidelines or publication policies. However, 18% of the journals reviewed identify a specific set of ethical guidelines to be followed before publishing research involving animals. Ethical considerations for investigators undertaking field research on fishes, common to most animal care policies, legislation and guiding documents, include adhering to relevant legislation, minimising sample sizes, reducing or mitigating pain and distress, employing the most appropriate and least invasive techniques and accurately reporting methods and findings. This information will provide potential investigators with a useful starting point for designing and conducting ethical field research. Application of ethical best practices in field sampling studies will improve the welfare of study animals and the conservation of rare and endangered species. Conservation implications: This article provides a list of ethical considerations for designing and conducting field research on fishes. By reviewing sampling techniques and processes that are frequently used in field research on fishes and by highlighting the potential negative impacts of these sampling techniques, this article is intended to assist researchers in planning

  19. TEMPORAL STRUCTURE OF OPEN-FIELD BEHAVIOR IN INBRED STRAINS OF MICE

    NARCIS (Netherlands)

    MAKINO, J; KATO, K; MAES, FW

    1991-01-01

    Behavior of the inbred mouse strains BALB, C3H, DBA and C57BL in an open field was directly observed for 10 min by a multi-event time sampling method. It was coded into nine behavioral items, the occurrence or absence of which in consecutive 5-s time bins was called a behavioral state. Fourteen

  20. Designing to bring the field to the showroom through open-ended provocation.

    NARCIS (Netherlands)

    Kelly, J.; Wensveen, S.A.G.

    2014-01-01

    Engaging formats are required to communicate designerly understandings of field studies to a broader audience within organisations. Here we present a case where the format of an exhibition, consisting of a collection of open-ended provocative design concepts, has been used to disseminate knowledge

  1. Behaviour in the open field predicts the number of KCl-induced cortical spreading depressions in rats

    OpenAIRE

    Bogdanov, Volodymyr Borysovych; Bogdanova, Olena Viktorivna; Koulchitsky, Stanislav Vladimirovich; Chauvel, Virginie; Multon, Sylvie; Makarchuk, Mykola Yukhymovych; Brennan, Kevin Christopher; Renshaw, Perry F.; Schoenen, Jean

    2012-01-01

    Anxiety disorders are known to be comorbid with migraine, and cortical spreading depression (CSD) is the most likely cause of the migraine aura. To search for possible correlations between susceptibility to CSD and anxiety we used the open field test in male Sprague-Dawley rats chronically treated with the preventive anti-migraine drugs valproate or riboflavin. Animals avoiding the central area of the open field chamber and those with less exploratory activity (i.e. rearing) were considered m...

  2. Probing two-field open inflation by resonant signals in correlation functions

    Energy Technology Data Exchange (ETDEWEB)

    Battefeld, Thorsten; Niemeyer, Jens C.; Vlaykov, Dimitar, E-mail: tbattefe@astro.physik.uni-goettingen.de, E-mail: niemeyer@astro.physik.uni-goettingen.de, E-mail: vlaykov@astro.physik.uni-goettingen.de [Institute for Astrophysics, University of Goettingen, Friedrich Hund Platz 1, D-37077 Goettingen (Germany)

    2013-05-01

    We derive oscillatory signals in correlation functions in two-field open inflation by means of the in-in formalism; such signatures are caused by resonances between oscillations in the tunnelling field and fluctuations in the inflaton during the curvature dominated, intermediate and subsequent inflationary regime. While amplitudes are model-dependent, we find distinct oscillations in the power and bi-spectrum that can act as a direct probe of the curvature dominated phase and thus, indirectly, strengthen the claim of the string landscape if they were observed. We comment on the prospects of detecting these tell-tale signs in current experiments, which is challenging, but not impossible. At the technical level, we pay special attention to the applicability conditions for truncating fluctuations to the light (inflaton) field and derive upper limits on the oscillation amplitude of the heavy field. A violation of these bounds requires a multi-field analysis at the perturbed level.

  3. Starting a Conversation about Open Data in Mathematics Education Research

    Science.gov (United States)

    Logan, Tracy

    2015-01-01

    This position paper discusses the role of open access research data within mathematics education, a relatively new initiative across the wider research community. International and national policy documents are explored and examples from both the scientific and social science paradigms of mathematical sciences and mathematics education…

  4. Electron polar cap and the boundary of open geomagnetic field lines.

    Science.gov (United States)

    Evans, L. C.; Stone, E. C.

    1972-01-01

    A total of 333 observations of the boundary of the polar access region for electrons (energies greater than 530 keV) provides a comprehensive map of the electron polar cap. The boundary of the electron polar cap, which should occur at the latitude separating open and closed field lines, is consistent with previously reported closed field line limits determined from trapped-particle data. The boundary, which is sharply defined, seems to occur at one of three discrete latitudes. Although the electron flux is generally uniform across the polar cap, a limited region of reduced access is observed about 10% of the time.

  5. Chronic Toxoplasma gondii in Nurr1-null heterozygous mice exacerbates elevated open field activity.

    Science.gov (United States)

    Eells, Jeffrey B; Varela-Stokes, Andrea; Guo-Ross, Shirley X; Kummari, Evangel; Smith, Holly M; Cox, Erin; Lindsay, David S

    2015-01-01

    Latent infection with Toxoplasma gondii is common in humans (approximately 30% of the global population) and is a significant risk factor for schizophrenia. Since prevalence of T. gondii infection is far greater than prevalence of schizophrenia (0.5-1%), genetic risk factors are likely also necessary to contribute to schizophrenia. To test this concept in an animal model, Nurr1-null heterozygous (+/-) mice and wild-type (+/+) mice were evaluate using an emergence test, activity in an open field and with a novel object, response to bobcat urine and prepulse inhibition of the acoustic startle response (PPI) prior to and 6 weeks after infection with T. gondii. In the emergence test, T. gondii infection significantly decreased the amount of time spent in the cylinder. Toxoplasma gondii infection significantly elevated open field activity in both +/+ and +/- mice but this increase was significantly exacerbated in +/- mice. T. gondii infection reduced PPI in male +/- mice but this was not statistically significant. Aversion to bobcat urine was abolished by T. gondii infection in +/+ mice. In female +/- mice, aversion to bobcat urine remained after T. gondii infection while the male +/- mice showed no aversion to bobcat urine. Antibody titers of infected mice were a critical variable associated with changes in open field activity, such that an inverted U shaped relationship existed between antibody titers and the percent change in open field activity with a significant increase in activity at low and medium antibody titers but no effect at high antibody titers. These data demonstrate that the Nurr1 +/- genotype predisposes mice to T. gondii-induced alterations in behaviors that involve dopamine neurotransmission and are associated with symptoms of schizophrenia. We propose that these alterations in murine behavior were due to further exacerbation of the altered dopamine neurotransmission in Nurr1 +/- mice.

  6. Chronic Toxoplasma gondii in Nurr1-null heterozygous mice exacerbates elevated open field activity.

    Directory of Open Access Journals (Sweden)

    Jeffrey B Eells

    Full Text Available Latent infection with Toxoplasma gondii is common in humans (approximately 30% of the global population and is a significant risk factor for schizophrenia. Since prevalence of T. gondii infection is far greater than prevalence of schizophrenia (0.5-1%, genetic risk factors are likely also necessary to contribute to schizophrenia. To test this concept in an animal model, Nurr1-null heterozygous (+/- mice and wild-type (+/+ mice were evaluate using an emergence test, activity in an open field and with a novel object, response to bobcat urine and prepulse inhibition of the acoustic startle response (PPI prior to and 6 weeks after infection with T. gondii. In the emergence test, T. gondii infection significantly decreased the amount of time spent in the cylinder. Toxoplasma gondii infection significantly elevated open field activity in both +/+ and +/- mice but this increase was significantly exacerbated in +/- mice. T. gondii infection reduced PPI in male +/- mice but this was not statistically significant. Aversion to bobcat urine was abolished by T. gondii infection in +/+ mice. In female +/- mice, aversion to bobcat urine remained after T. gondii infection while the male +/- mice showed no aversion to bobcat urine. Antibody titers of infected mice were a critical variable associated with changes in open field activity, such that an inverted U shaped relationship existed between antibody titers and the percent change in open field activity with a significant increase in activity at low and medium antibody titers but no effect at high antibody titers. These data demonstrate that the Nurr1 +/- genotype predisposes mice to T. gondii-induced alterations in behaviors that involve dopamine neurotransmission and are associated with symptoms of schizophrenia. We propose that these alterations in murine behavior were due to further exacerbation of the altered dopamine neurotransmission in Nurr1 +/- mice.

  7. Displacement and stress fields around rock fractures opened by irregular overpressure variations

    Directory of Open Access Journals (Sweden)

    Shigekazu eKusumoto

    2014-05-01

    Full Text Available Many rock fractures are entirely driven open by fluids such as ground water, geothermal water, gas, oil, and magma. These are a subset of extension fractures (mode I cracks; e.g., dikes, mineral veins and joints referred to as hydrofractures. Field measurements show that many hydrofractures have great variations in aperture. However, most analytical solutions for fracture displacement and stress fields assume the loading to be either constant or with a linear variation. While these solutions have been widely used, it is clear that a fracture hosted by heterogeneous and anisotropic rock is normally subject to loading that is neither constant nor with a linear variation. Here we present new general solutions for the displacement and stress fields around hydrofractures, modelled as two-dimensional elastic cracks, opened by irregular overpressure variations given by the Fourier cosine series. Each solution has two terms. The first term gives the displacement and stress fields due to the average overpressure acting inside the crack; it is given by the initial term of the Fourier coefficients expressing the overpressure variation. The second term gives the displacement and stress fields caused by the overpressure variation; it is given by general terms of the Fourier coefficients and solved through numerical integration. Our numerical examples show that the crack aperture variation closely reflects the overpressure variation. Also, that the general displacement and stress fields close to the crack follow the overpressure variation but tend to be more uniform far from the crack. The present solutions can be used to estimate the displacement and stress fields around any fluid-driven crack, that is, any hydrofracture, as well as its aperture, provided the variation in overpressure can be described by Fourier series. The solutions add to our understanding of local stresses, displacements, and fluid transport associated with hydrofractures in the crust.

  8. Evidence-based severity assessment: Impact of repeated versus single open-field testing on welfare in C57BL/6J mice.

    Science.gov (United States)

    Bodden, Carina; Siestrup, Sophie; Palme, Rupert; Kaiser, Sylvia; Sachser, Norbert; Richter, S Helene

    2018-01-15

    According to current guidelines on animal experiments, a prospective assessment of the severity of each procedure is mandatory. However, so far, the classification of procedures into different severity categories mainly relies on theoretic considerations, since it is not entirely clear which of the various procedures compromise the welfare of animals, or, to what extent. Against this background, a systematic empirical investigation of the impact of each procedure, including behavioral testing, seems essential. Therefore, the present study was designed to elucidate the effects of repeated versus single testing on mouse welfare, using one of the most commonly used paradigms for behavioral phenotyping in behavioral neuroscience, the open-field test. In an independent groups design, laboratory mice (Mus musculus f. domestica) experienced either repeated, single, or no open-field testing - procedures that are assigned to different severity categories. Interestingly, testing experiences did not affect fecal corticosterone metabolites, body weights, elevated plus-maze or home cage behavior differentially. Thus, with respect to the assessed endocrinological, physical, and behavioral outcome measures, no signs of compromised welfare could be detected in mice that were tested in the open-field repeatedly, once, or, not at all. These findings challenge current classification guidelines and may, furthermore, stimulate systematic research on the severity of single procedures involving living animals. Copyright © 2017 Elsevier B.V. All rights reserved.

  9. Linear b-gauges for open string fields

    International Nuclear Information System (INIS)

    Kiermaier, Michael; Zwiebach, Barton; Sen, Ashoke

    2008-01-01

    Motivated by Schnabl's gauge choice, we explore open string perturbation theory in gauges where a linear combination of antighost oscillators annihilates the string field. We find that in these linear b-gauges different gauge conditions are needed at different ghost numbers. We derive the full propagator and prove the formal properties which guarantee that the Feynman diagrams reproduce the correct on-shell amplitudes. We find that these properties can fail due to the need to regularize the propagator, and identify a large class of linear b-gauges for which they hold rigorously. In these gauges the propagator has a non-anomalous Schwinger representation and builds Riemann surfaces by adding strip-like domains. Projector-based gauges, like Schnabl's, are not in this class of gauges but we construct a family of regular linear b-gauges which interpolate between Siegel gauge and Schnabl gauge

  10. Standardized UXO Technology Demonstration Site Open Field Scoring Record Number 492 (Shaw Environmental, Inc.)

    National Research Council Canada - National Science Library

    Overbay, Larry; Robitaille, George

    2005-01-01

    ...) utilizing the APG Standardized UXO Technology Demonstration Site Open Field. Scoring Records have been coordinated by Larry Overbay and the Standardized UXO Technology Demonstration Site Scoring Committee...

  11. Standardized UXO Technology Demonstration Site Open Field Scoring Record Number 668 (NAEVA Geophysics, Inc.)

    National Research Council Canada - National Science Library

    Overbay, Larry; Robitaille, George

    2005-01-01

    ...) utilizing they PG Standardized UXO Technology Demonstration Site Open Field. Scoring Records have been coordinate by Larry Overbay and the Standardized UXO Technology Demonstration Site Scoring Committee...

  12. Social Effects on Rat Spatial Choice in an Open Field Task

    Science.gov (United States)

    Keller, Matthew R.; Brown, Michael F.

    2011-01-01

    Pairs of rats foraged in trials either together or separately in an open field apparatus for pellets hidden in discreet locations in a 5 x 5 matrix. Trial duration was either 1 or 4 min. The tendency to choose locations that had earlier been visited by another rat was examined by comparing the choices made in the presence and absence of the other…

  13. Agricultural and Management Practices and Bacterial Contamination in Greenhouse versus Open Field Lettuce Production

    Science.gov (United States)

    Holvoet, Kevin; Sampers, Imca; Seynnaeve, Marleen; Jacxsens, Liesbeth; Uyttendaele, Mieke

    2014-01-01

    The aim of this study was to gain insight into potential differences in risk factors for microbial contamination in greenhouse versus open field lettuce production. Information was collected on sources, testing, and monitoring and if applicable, treatment of irrigation and harvest rinsing water. These data were combined with results of analysis on the levels of Escherichia coli as a fecal indicator organism and the presence of enteric bacterial pathogens on both lettuce crops and environmental samples. Enterohemorragic Escherichia coli (EHEC) PCR signals (vt1 or vt2 positive and eae positive), Campylobacter spp., and Salmonella spp. isolates were more often obtained from irrigation water sampled from open field farms (21/45, 46.7%) versus from greenhouse production (9/75, 12.0%). The open field production was shown to be more prone to fecal contamination as the number of lettuce samples and irrigation water with elevated E. coli was significantly higher. Farmers comply with generic guidelines on good agricultural practices available at the national level, but monitoring of microbial quality, and if applicable appropriateness of water treatment, or water used for irrigation or at harvest is restricted. These results indicate the need for further elaboration of specific guidelines and control measures for leafy greens with regard to microbial hazards. PMID:25546272

  14. Developing research career indicators using open data: the RISIS infrastructure

    Energy Technology Data Exchange (ETDEWEB)

    Cañibano, C.; Woolley, R.; Iversen, E.; Hinze, S.; Hornbostel, S.; Tesch, J.

    2016-07-01

    This paper introduces the research infrastructure for rsearch and innovation policy studies (RISIS) and its ongoing work on the development of indicators for research careers. The paper first describes the rationale for developing an information system on research careers. It then uses and example to demonstratate the possibilities arising from aggregating open data from different datasets within the RISIS platform to create new information and monitoring possibilies with regard to research careers. (Author)

  15. Magnetic field effects on the open circuit potential of ferromagnetic electrodes in corroding solutions.

    Science.gov (United States)

    Dass, Amala; Counsil, Joseph A; Gao, Xuerong; Leventis, Nicholas

    2005-06-02

    Magnetic fields shift the open circuit potential (OCP) of ferromagnetic electrodes (Fe, Co, and Ni) in corroding solutions. The OCP changes we observe (a) follow the series Fe>Co>Ni; (b) increase with the magnetic flux density; (c) reach a maximum with disk electrodes approximately 1 mm in diameter; and (d) depend on the orientation of the electrode. We report that when the surface of the electrode is oriented parallel (theta = 90 degrees) or perpendicular (theta = 0 degrees) to the magnetic field, the open circuit potential moves in opposite directions (positive and negative, respectively) with the largest changes occurring when the electrode surface is parallel to the magnetic field. Nonconvective sleeve electrodes produce the same behavior. The overall experimental evidence suggests that the magnetic field changes the OCP by modifying the surface concentrations of the paramagnetic participants in the corrosion process of the ferromagnetic electrode by species in solution; this in turn is accomplished by imposing a field-gradient driven mode of mass transfer upon paramagnetic species in solution (magnetophoresis). Simulations of the magnetic field around the ferromagnetic electrode at the two extreme orientations considered here show that in one case (theta = 90 degrees) field gradients actually repel, while in the other case (theta = 0 degrees) they attract paramagnetic species in the vicinity of the electrode.

  16. [C57BL/6 mice open field behaviour qualitatively depends on arena size].

    Science.gov (United States)

    Lebedev, I V; Pleskacheva, M G; Anokhin, K V

    2012-01-01

    Open field behavior is well known to depend on physical characteristics of the apparatus. However many of such effects are poorly described especially with using of modern methods of behavioral registration and analysis. The previous results of experiments on the effect of arena size on behavior are not numerous and contradictory. We compared the behavioral scores of four groups of C57BL/6 mice in round open field arenas of four different sizes (diameter 35, 75, 150 and 220 cm). The behavior was registered and analyzed using Noldus EthoVision, WinTrack and SegmentAnalyzer software. A significant effect of arena size was found. Traveled distance and velocity increased, but not in proportion to increase of arena size. Moreover a significant effect on segment characteristics of the trajectory was revealed. Detailed behavior analysis revealed drastic differences in trajectory structure and number of rears between smaller (35 and 75 cm) and bigger (150 and 220 cm) arenas. We conclude, that the character of exploration in smaller and bigger arenas depends on relative size of central open zone in arena. Apparently its extension increases the motivational heterogeneity of space, that requires another than in smaller arenas, strategy of exploration.

  17. Pulsed power opening switch research at the University of New Mexico

    International Nuclear Information System (INIS)

    Humphries, S. Jr.

    1987-01-01

    Opening switch research at the University of New Mexico (UNM) is directed toward moderate-current (--10 kA) devices with potential applications to high-power charged particle accelerators. Two devices with the capacity for controlling gigawatt high-voltage circuits, the grid-controlled plasma flow switch and the scanned-beam switch, are under investigation. Both switches are conceptually simple; they involve little collective physics and are within the capabilities of current technology. In the plasma flow switch, the flux of electrons into a high-voltage power gap is controlled by a low-voltage control grid. Plasma generation is external to, and independent of, the power circuit. In the closed phase, plasma fills the gap so that the switch has a low on-state impedance. Pulse repetition rates in the megahertz range should be feasible. In single-shot proof-of-principle experiments, a small area switch modulated a 3-MW circuit; a 20-ns opening time was observed. The scanned-beam switch will utilize electric field deflection to direct the power of a sheet electron beam. The beam is to be alternately scanned to two inverse diodes connected to output transmission lines. The switch is expected to generate continuous-wave pulse trains for applications such as high-frequency induction linacs. Theoretical studies indicate that 10-GW devices in the 100-MHz range with 70-percent efficiency should be technologically feasible

  18. Field Trial of 40 Gb/s Optical Transport Network using Open WDM Interfaces

    DEFF Research Database (Denmark)

    Fagertun, Anna Manolova; Ruepp, Sarah Renée; Petersen, Martin Nordal

    2013-01-01

    An experimental field-trail deployment of a 40Gb/s open WDM interface in an operational network is presented, in cross-carrier interconnection scenario. Practical challenges of integration and performance measures for both native and alien channels are outlined....

  19. Pioneering SESAME light source officially opened

    CERN Multimedia

    Caraban Gonzalez, Noemi

    2017-01-01

    Allan, Jordan, 16 May 2017. The SESAME light source was today officially opened by His Majesty King Abdullah II. An intergovernmental organization, SESAME is the first regional laboratory for the Middle East and neighbouring regions The laboratory’s official opening ushers in a new era of research covering fields ranging from medicine and biology, through materials science, physics and chemistry to healthcare, the environment, agriculture and archaeology.

  20. From translational research to open technology innovation systems.

    Science.gov (United States)

    Savory, Clive; Fortune, Joyce

    2015-01-01

    The purpose of this paper is to question whether the emphasis placed within translational research on a linear model of innovation provides the most effective model for managing health technology innovation. Several alternative perspectives are presented that have potential to enhance the existing model of translational research. A case study is presented of innovation of a clinical decision support system. The paper concludes from the case study that an extending the triple helix model of technology transfer, to one based on a quadruple helix, present a basis for improving the performance translational research. A case study approach is used to help understand development of an innovative technology within a teaching hospital. The case is then used to develop and refine a model of the health technology innovation system. The paper concludes from the case study that existing models of translational research could be refined further through the development of a quadruple helix model of heath technology innovation that encompasses greater emphasis on user-led and open innovation perspectives. The paper presents several implications for future research based on the need to enhance the model of health technology innovation used to guide policy and practice. The quadruple helix model of innovation that is proposed can potentially guide alterations to the existing model of translational research in the healthcare sector. Several suggestions are made for how innovation activity can be better supported at both a policy and operational level. This paper presents a synthesis of the innovation literature applied to a theoretically important case of open innovation in the UK National Health Service. It draws in perspectives from other industrial sectors and applies them specifically to the management and organisation of innovation activities around health technology and the services in which they are embedded.

  1. Open geospatial infrastructure for data management and analytics in interdisciplinary research

    DEFF Research Database (Denmark)

    Jeppesen, Jacob Høxbroe; Ebeid, Emad Samuel Malki; Jacobsen, Rune Hylsberg

    2018-01-01

    , and information and communications technology needed to promote the implementation of precision agriculture is limited by proprietary integrations and non-standardized data formats and connections. In this paper, an open geospatial data infrastructure is presented, based on standards defined by the Open...... software, and was complemented by open data from governmental offices along with ESA satellite imagery. Four use cases are presented, covering analysis of nearly 50 000 crop fields and providing seamless interaction with an emulated machine terminal. They act to showcase both for how the infrastructure......The terms Internet of Things and Big Data are currently subject to much attention, though the specific impact of these terms in our practical lives are difficult to apprehend. Data-driven approaches do lead to new possibilities, and significant improvements within a broad range of domains can...

  2. An open future for ecological and evolutionary data?

    Science.gov (United States)

    Kenall, Amye; Harold, Simon; Foote, Christopher

    2014-04-02

    As part of BioMed Central's open science mission, we are pleased to announce that two of our journals have integrated with the open data repository Dryad. Authors submitting their research to either BMC Ecology or BMC Evolutionary Biology will now have the opportunity to deposit their data directly into the Dryad archive and will receive a permanent, citable link to their dataset. Although this does not affect any of our current data deposition policies at these journals, we hope to encourage a more widespread adoption of open data sharing in the fields of ecology and evolutionary biology by facilitating this process for our authors. We also take this opportunity to discuss some of the wider issues that may concern researchers when making their data openly available. Although we offer a number of positive examples from different fields of biology, we also recognise that reticence to data sharing still exists, and that change must be driven from within research communities in order to create future science that is fit for purpose in the digital age. This editorial was published jointly in both BMC Ecology and BMC Evolutionary Biology.

  3. Specvis: Free and open-source software for visual field examination.

    Science.gov (United States)

    Dzwiniel, Piotr; Gola, Mateusz; Wójcik-Gryciuk, Anna; Waleszczyk, Wioletta J

    2017-01-01

    Visual field impairment affects more than 100 million people globally. However, due to the lack of the access to appropriate ophthalmic healthcare in undeveloped regions as a result of associated costs and expertise this number may be an underestimate. Improved access to affordable diagnostic software designed for visual field examination could slow the progression of diseases, such as glaucoma, allowing for early diagnosis and intervention. We have developed Specvis, a free and open-source application written in Java programming language that can run on any personal computer to meet this requirement (http://www.specvis.pl/). Specvis was tested on glaucomatous, retinitis pigmentosa and stroke patients and the results were compared to results using the Medmont M700 Automated Static Perimeter. The application was also tested for inter-test intrapersonal variability. The results from both validation studies indicated low inter-test intrapersonal variability, and suitable reliability for a fast and simple assessment of visual field impairment. Specvis easily identifies visual field areas of zero sensitivity and allows for evaluation of its levels throughout the visual field. Thus, Specvis is a new, reliable application that can be successfully used for visual field examination and can fill the gap between confrontation and perimetry tests. The main advantages of Specvis over existing methods are its availability (free), affordability (runs on any personal computer), and reliability (comparable to high-cost solutions).

  4. International survey of research university leadership views on supporting open access scholarly & educational materials

    CERN Document Server

    2017-01-01

    This report looks closely at the attitudes on open access of a sample of 314 deans, chancellors, department chairmen, research institute directors, provosts, trustees, vice presidents and other upper level administrators from more than 50 research universities in the USA, Canada, the UK, Ireland and Australia. The report gives detailed information on what they think of the cost of academic journal subscriptions, and how they understand the meaning of the term “open access.” The study also gives highly detailed data on what kind of policies the research university elite support or might support in the area of open access, including policies such as restricting purchases of very high-priced journals, paying publication fees for open access publications, mandating deposit of university scholarship into digital repositories, and developing open access educational materials from university resources. Just a few of the report’s many findings are that: • The lowest percentage of those interviewed considering...

  5. Duke Surgery Research Central: an open-source Web application for the improvement of compliance with research regulation.

    Science.gov (United States)

    Pietrobon, Ricardo; Shah, Anand; Kuo, Paul; Harker, Matthew; McCready, Mariana; Butler, Christeen; Martins, Henrique; Moorman, C T; Jacobs, Danny O

    2006-07-27

    Although regulatory compliance in academic research is enforced by law to ensure high quality and safety to participants, its implementation is frequently hindered by cost and logistical barriers. In order to decrease these barriers, we have developed a Web-based application, Duke Surgery Research Central (DSRC), to monitor and streamline the regulatory research process. The main objective of DSRC is to streamline regulatory research processes. The application was built using a combination of paper prototyping for system requirements and Java as the primary language for the application, in conjunction with the Model-View-Controller design model. The researcher interface was designed for simplicity so that it could be used by individuals with different computer literacy levels. Analogously, the administrator interface was designed with functionality as its primary goal. DSRC facilitates the exchange of regulatory documents between researchers and research administrators, allowing for tasks to be tracked and documents to be stored in a Web environment accessible from an Intranet. Usability was evaluated using formal usability tests and field observations. Formal usability results demonstrated that DSRC presented good speed, was easy to learn and use, had a functionality that was easily understandable, and a navigation that was intuitive. Additional features implemented upon request by initial users included: extensive variable categorization (in contrast with data capture using free text), searching capabilities to improve how research administrators could search an extensive number of researcher names, warning messages before critical tasks were performed (such as deleting a task), and confirmatory e-mails for critical tasks (such as completing a regulatory task). The current version of DSRC was shown to have excellent overall usability properties in handling research regulatory issues. It is hoped that its release as an open-source application will promote improved

  6. Duke Surgery Research Central: an open-source Web application for the improvement of compliance with research regulation

    Directory of Open Access Journals (Sweden)

    Martins Henrique

    2006-07-01

    Full Text Available Abstract Background Although regulatory compliance in academic research is enforced by law to ensure high quality and safety to participants, its implementation is frequently hindered by cost and logistical barriers. In order to decrease these barriers, we have developed a Web-based application, Duke Surgery Research Central (DSRC, to monitor and streamline the regulatory research process. Results The main objective of DSRC is to streamline regulatory research processes. The application was built using a combination of paper prototyping for system requirements and Java as the primary language for the application, in conjunction with the Model-View-Controller design model. The researcher interface was designed for simplicity so that it could be used by individuals with different computer literacy levels. Analogously, the administrator interface was designed with functionality as its primary goal. DSRC facilitates the exchange of regulatory documents between researchers and research administrators, allowing for tasks to be tracked and documents to be stored in a Web environment accessible from an Intranet. Usability was evaluated using formal usability tests and field observations. Formal usability results demonstrated that DSRC presented good speed, was easy to learn and use, had a functionality that was easily understandable, and a navigation that was intuitive. Additional features implemented upon request by initial users included: extensive variable categorization (in contrast with data capture using free text, searching capabilities to improve how research administrators could search an extensive number of researcher names, warning messages before critical tasks were performed (such as deleting a task, and confirmatory e-mails for critical tasks (such as completing a regulatory task. Conclusion The current version of DSRC was shown to have excellent overall usability properties in handling research regulatory issues. It is hoped that its

  7. Tensions between opening up and closing down moments in transdisciplinary water research

    Science.gov (United States)

    Krueger, Tobias; Maynard, Carly; Carr, Gemma; Bruns, Antje; Mueller, Eva; Lane, Stuart

    2016-04-01

    Research on water is carried out by many disciplines that do not really talk to each other much, despite critical interactions of multiple social and biophysical processes in shaping how much and what kind of water is where, at what time and for whom. What is more, water has meaning to more than those who are scientists. And scientists are not so removed from the things they study as one might commonly believe. All these observations call for a transdisciplinary research agenda that brings together different scientific disciplines with the knowledge that other groups in society hold and that tries to be aware of its own limitations. The transdisciplinary perspective is especially pertinent to the scientific decade 2013-2022 of the International Association of Hydrological Sciences (IAHS) on change in hydrology and society, 'Panta Rhei,' for a balanced conceptualization and study of human-water relations. Transdisciplinarity is inherently about opening up traditional modes of knowledge production; in terms of framing the research problem, the methodology and the knowledge that is considered permissible. This should open up the range of options for management intervention, too. While decisions on how to intervene will inevitably close down the issue periodically, the point here is to leave alternative routes of action open long enough, or reopen them again, so as to counter unsustainable and inequitable path-dependencies and lock-ins. However, opening up efforts are frequently in conflict with factors that work to close down knowledge production. Among those are framings, path-dependencies, vested interests, researchers' positionalities, power, and scale. In this presentation, based on Krueger et al. (2016), we will reflect on the tensions between opening up and closing down moments in transdisciplinary water research and draw important practical lessons. References Krueger, T., Maynard, C.M., Carr, G., Bruns, A., Mueller, E.N. and Lane, S.N. (forthcoming in 2016) A

  8. Deriving the four-string and open-closed string interactions from geometric string field theory

    International Nuclear Information System (INIS)

    Kaku, M.

    1990-01-01

    One of the questions concerning the covariant open string field theory is why there are two distinct BRST theories and why the four-string interaction appears in one version but not the other. The authors solve this mystery by showing that both theories are gauge-fixed versions of a higher gauge theory, called the geometric string field theory, with a new field, a string verbein e μσ νρ , which allows us to gauge the string length and σ parametrization. By fixing the gauge, the authors can derive the endpoint gauge (the covariantized light cone gauge), the midpoint gauge of Witten, or the interpolating gauge with arbitrary string length. The authors show explicitly that the four-string interaction is a gauge artifact of the geometric theory (the counterpart of the four-fermion instantaneous Coulomb term of QED). By choosing the interpolating gauge, they produce a new class of four-string interactions which smoothly interpolate between the endpoint gauge and the midpoint gauge (where it vanishes). Similarly, they can extract the closed string as a bound state of the open string, which appears in the endpoint gauge but vanishes in the midpoint gauge. Thus, the four-string and open-closed string interactions do not have to be added to the action as long as the string vierbein is included

  9. Conducting Field Research on Terrorism: a Brief Primer

    Directory of Open Access Journals (Sweden)

    Adam Dolnik

    2011-05-01

    Full Text Available This article focuses on the practical aspects of field research on terrorism. Firstly, it  outlines some issues involved in the process of attaining a human research ethics/institutional review board clearance in order to be able to even begin the field research. It suggests some ways in which researchers can positively influence this review process in their favor. Secondly, the article focuses on the real and perceived dangers of field research, identifying practical steps and preparatory activities that can help researchers manage and reduce the risks involved. The article also covers the formalities and dilemmas involved in gaining access to the field. It then provides some insights into the topic of operating in conflict zones, followed by a section covering the ways of gaining access to sources, effective communication skills and influence techniques and addresses key issues involved in interviewing sources in the field. The final section focuses on identifying biases and interfering factors which researchers need to take into account when interpreting the data acquired through interviews. This article is a modest attempt to fill a gap in the literature on terrorism research by outlining some of the key issues involved in the process of doing field research. It incorporates insights from diverse disciplines as well as the author’s personal experiences of conducting field research on terrorism in places like Afghanistan, Pakistan, Chechnya, Ingushetia, Colombia, Mindanao, Uganda, Indonesia, Democratic Republic of Congo, Sudan, and India.

  10. The behaviour of the paradise fish (Macropodus opercularis) in two different open-fields. A correlation study.

    Science.gov (United States)

    Gerlai, R; Csányi, V

    1987-01-01

    The behaviour of the paradise fish in a traditional "closed" and in a new "transparent" open-field was investigated. The traditional way of measuring ambulation scores was extended by recording ethologically defined behaviour units. The correlations found between the scores measured in the "closed" field and those measured in the "transparent" field are discussed in this paper.

  11. Opening Digital Archives and Collections with Emerging Data Analytics Technology: A Research Agenda

    Directory of Open Access Journals (Sweden)

    Ahmed Elragal

    2017-02-01

    Full Text Available In the public sector, the EU legislation requires preservation and opening of increasing amounts of heterogeneous digital information that should be utilized by citizens and businesses. While technologies such as big data analytics (BDA have emerged, opening of digital archives and collections at a large scale is in its infancy. Opening archives and collections involve also particular requirements for recognizing and managing issues of privacy and digital rights. As well, ensuring the sustainability of the opened materials and economical appraisal of digital materials for preservation require robust digital preservation practices. We need to proceed beyond the state-of-the-art in opening digital archives and collections through the means of emerging big data analytics and validating a novel concept for analytics which then enables delivering of knowledge for citizens and the society. We set out an agenda for using BDA as our strategy for research and enquiry and for demonstrating the benefit of BDA for opening digital archives by civil servants and for citizens. That will – eventually - transform the preservation practices, and delivery and use opportunities of public digital archives. Our research agenda suggests a framework integrating four domains of inquiry, analytics-enhanced appraisal, analytics-prepared preservation, analytics-enhanced opening, and analytics-enhanced use, for utilizing the BDA technologies in the domain of digital archives and collections. The suggested framework and research agenda identifies initially particular BDA technologies to be utilized in each of the four domains, and contributes by highlighting a need for an integrated “public understanding of big data” in the domain of digital preservation.

  12. Public open space, physical activity, urban design and public health: Concepts, methods and research agenda.

    Science.gov (United States)

    Koohsari, Mohammad Javad; Mavoa, Suzanne; Villanueva, Karen; Sugiyama, Takemi; Badland, Hannah; Kaczynski, Andrew T; Owen, Neville; Giles-Corti, Billie

    2015-05-01

    Public open spaces such as parks and green spaces are key built environment elements within neighbourhoods for encouraging a variety of physical activity behaviours. Over the past decade, there has been a burgeoning number of active living research studies examining the influence of public open space on physical activity. However, the evidence shows mixed associations between different aspects of public open space (e.g., proximity, size, quality) and physical activity. These inconsistencies hinder the development of specific evidence-based guidelines for urban designers and policy-makers for (re)designing public open space to encourage physical activity. This paper aims to move this research agenda forward, by identifying key conceptual and methodological issues that may contribute to inconsistencies in research examining relations between public open space and physical activity. Copyright © 2015 Elsevier Ltd. All rights reserved.

  13. Early diagnosis and research of high myopia with primary open angle glaucoma

    Directory of Open Access Journals (Sweden)

    Yan Guo

    2014-04-01

    Full Text Available People with high myopia are high risk populations to have primary open angle glaucoma. Clinically, we found that patients with primary open angle glaucoma and high myopia is closely related. So to understand the clinical features of high myopia with primary open angle glaucoma and the importance of early diagnosis, to avoiding missed diagnosis or lower misdiagnosed rate, can help to improve the vigilance and level of early diagnosis of the clinicians. In this paper, high myopia with clinical features of primary open angle glaucoma, and the research progress on the main points of early diagnosis were reviewed.

  14. Seedling Emergence and Phenotypic Response of Common Bean Germplasm to Different Temperatures under Controlled Conditions and in Open Field.

    Science.gov (United States)

    De Ron, Antonio M; Rodiño, Ana P; Santalla, Marta; González, Ana M; Lema, María J; Martín, Isaura; Kigel, Jaime

    2016-01-01

    Rapid and uniform seed germination and seedling emergence under diverse environmental conditions is a desirable characteristic for crops. Common bean genotypes (Phaseolus vulgaris L.) differ in their low temperature tolerance regarding growth and yield. Cultivars tolerant to low temperature during the germination and emergence stages and carriers of the grain quality standards demanded by consumers are needed for the success of the bean crop. The objectives of this study were (i) to screen the seedling emergence and the phenotypic response of bean germplasm under a range of temperatures in controlled chamber and field conditions to display stress-tolerant genotypes with good agronomic performances and yield potential, and (ii) to compare the emergence of bean seedlings under controlled environment and in open field conditions to assess the efficiency of genebanks standard germination tests for predicting the performance of the seeds in the field. Three trials were conducted with 28 dry bean genotypes in open field and in growth chamber under low, moderate, and warm temperature. Morpho-agronomic data were used to evaluate the phenotypic performance of the different genotypes. Cool temperatures resulted in a reduction of the rate of emergence in the bean genotypes, however, emergence and early growth of bean could be under different genetic control and these processes need further research to be suitably modeled. Nine groups arose from the Principal Component Analysis (PCA) representing variation in emergence time and proportion of emergence in the controlled chamber and in the open field indicating a trend to lower emergence in large and extra-large seeded genotypes. Screening of seedling emergence and phenotypic response of the bean germplasm under a range of temperatures in controlled growth chambers and under field conditions showed several genotypes, as landraces 272, 501, 593, and the cultivar Borlotto, with stress-tolerance at emergence, and high yield

  15. Seedling Emergence and Phenotypic Response of Common Bean Germplasm to Different Temperatures under Controlled Conditions and in Open Field

    Directory of Open Access Journals (Sweden)

    Antonio M. DE RON

    2016-08-01

    Full Text Available Rapid and uniform seed germination and seedling emergence under diverse environmental conditions is a desirable characteristic for crops. Common bean genotypes (Phaseolus vulgaris L. differ in their low temperature tolerance regarding growth and yield. Cultivars tolerant to low temperature during the germination and emergence stages and carriers of the grain quality standards demanded by consumers are needed for the success of the bean crop. The objectives of this study were i to screen the seedling emergence and the phenotypic response of bean germplasm under a range of temperatures in controlled chamber and field conditions to display stress-tolerant genotypes with good agronomic performances and yield potential, and ii to compare the emergence of bean seedlings under controlled environment and in open field conditions to assess the efficiency of genebanks standard germination tests for predicting the performance of the seeds in the field. Three trials were conducted with 28 dry bean genotypes in open field and in growth chamber under low, moderate and warm temperature. Morpho-agronomic data were used to evaluate the phenotypic performance of the different genotypes. Cool temperatures resulted in a reduction of the rate of emergence in the bean genotypes, however, emergence and early growth of bean could be under different genetic control and these processes need further research to be suitably modeled. Nine groups arose from the Principal Component Analysis (PCA representing variation in emergence time and proportion of emergence in the controlled chamber and in the open field indicating a trend to lower emergence in large and extra-large seeded genotypes. Screening of seedling emergence and phenotypic response of the bean germplasm under a range of temperatures in controlled growth chambers and under field conditions showed several genotypes, as landraces 272, 501, 593 and the cultivar Borlotto, with stress-tolerance at emergence and high

  16. Oxygen plasma assisted end-opening and field emission enhancement in vertically aligned multiwall carbon nanotubes

    International Nuclear Information System (INIS)

    Mathur, A.; Roy, S.S.; Hazra, K.S.; Wadhwa, S.; Ray, S.C.; Mitra, S.K.; Misra, D.S.; McLaughlin, J.A.

    2012-01-01

    Highlights: ► We showed Ar/O 2 plasma can be effective for the end opening of aligned CNTs. ► The field emission property was dramatically enhanced after plasma modification. ► Microstructures were clearly understood by Raman and SEM analysis. ► Surface wet-ability at various functionalised conditions was studied. - Abstract: This paper highlights the changes in micro-structural and field emission properties of vertically aligned carbon nanotubes (VACNTs) via oxygen plasma treatment. We find that exposure of very low power oxygen plasma (6 W) at 13.56 MHz for 15–20 min, opens the tip of vertically aligned CNTs. Scanning electron microscopy and transmission electron microscopy images were used to identify the quality and micro-structural changes of the nanotube morphology and surfaces. Raman spectra showed that the numbers of defects were increased throughout the oxygen plasma treatment process. In addition, the hydrophobic nature of the VACNTs is altered significantly and the contact angle decreases drastically from 110° to 40°. It was observed that the electron field emission (EFE) characteristics are significantly enhanced. The turn-on electric field (ETOE) of CNTs decreased from ∼0.80 V μm −1 (untreated) to ∼0.60 V μm −1 (oxygen treated). We believe that the open ended VACNTs would be immensely valuable for applications such as micro/nanofluidic based filtering elements and display devices.

  17. Oxygen plasma assisted end-opening and field emission enhancement in vertically aligned multiwall carbon nanotubes

    Energy Technology Data Exchange (ETDEWEB)

    Mathur, A. [NIBEC, School of Engineering, University of Ulster, Jordanstown, BT37 0QB (United Kingdom); Roy, S.S., E-mail: sinharoy@ualberta.ca [Department of Mechanical Engineering, University of Alberta, Edmonton, T6T 2G8 (Canada); Hazra, K.S. [Department of Physics, IIT Bombay, Powai, Mumbai-400076 (India); Wadhwa, S. [NIBEC, School of Engineering, University of Ulster, Jordanstown, BT37 0QB (United Kingdom); Ray, S.C. [School of Physics, University of the Witwatersrand, WITS 2050, Johannesburg (South Africa); Mitra, S.K. [Department of Mechanical Engineering, University of Alberta, Edmonton, T6T 2G8 (Canada); Misra, D.S. [Department of Physics, IIT Bombay, Powai, Mumbai-400076 (India); McLaughlin, J.A. [NIBEC, School of Engineering, University of Ulster, Jordanstown, BT37 0QB (United Kingdom)

    2012-05-15

    Highlights: Black-Right-Pointing-Pointer We showed Ar/O{sub 2} plasma can be effective for the end opening of aligned CNTs. Black-Right-Pointing-Pointer The field emission property was dramatically enhanced after plasma modification. Black-Right-Pointing-Pointer Microstructures were clearly understood by Raman and SEM analysis. Black-Right-Pointing-Pointer Surface wet-ability at various functionalised conditions was studied. - Abstract: This paper highlights the changes in micro-structural and field emission properties of vertically aligned carbon nanotubes (VACNTs) via oxygen plasma treatment. We find that exposure of very low power oxygen plasma (6 W) at 13.56 MHz for 15-20 min, opens the tip of vertically aligned CNTs. Scanning electron microscopy and transmission electron microscopy images were used to identify the quality and micro-structural changes of the nanotube morphology and surfaces. Raman spectra showed that the numbers of defects were increased throughout the oxygen plasma treatment process. In addition, the hydrophobic nature of the VACNTs is altered significantly and the contact angle decreases drastically from 110 Degree-Sign to 40 Degree-Sign . It was observed that the electron field emission (EFE) characteristics are significantly enhanced. The turn-on electric field (ETOE) of CNTs decreased from {approx}0.80 V {mu}m{sup -1} (untreated) to {approx}0.60 V {mu}m{sup -1} (oxygen treated). We believe that the open ended VACNTs would be immensely valuable for applications such as micro/nanofluidic based filtering elements and display devices.

  18. Infant titi monkey behavior in the open field test and the effect of early adversity.

    Science.gov (United States)

    Larke, Rebecca H; Toubiana, Alice; Lindsay, Katrina A; Mendoza, Sally P; Bales, Karen L

    2017-09-01

    The open field test is commonly used to measure anxiety-related behavior and exploration in rodents. Here, we used it as a standardized novel environment in which to evaluate the behavioral response of infant titi monkeys (Callicebus cupreus), to determine the effect of presence of individual family members, and to assess how adverse early experience alters infant behavior. Infants were tested in the open field for 5 days at ages 4 and 6 months in four successive 5 min trials on each day. A transport cage, which was situated on one side of the open field, was either empty (non-social control) or contained the father, mother, or sibling. Infant locomotor, vocalization, and exploratory behavior were quantified. Results indicated that age, sex, social condition, and early experience all had significant effects on infant behavior. Specifically, infants were generally more exploratory at 6 months and male infants were more exploratory than females. Infants distinguished between social and non-social conditions but made few behavioral distinctions between the attachment figure and other individuals. Infants which had adverse early life experience demonstrated greater emotional and physical independence, suggesting that early adversity led to resiliency in the novel environment. © 2017 Wiley Periodicals, Inc.

  19. [Effects of psychological stress on performances in open-field test of rats and tyrosine's modulation].

    Science.gov (United States)

    Chen, Wei-Qiang; Cheng, Yi-Yong; Li, Shu-Tian; Hong, Yan; Wang, Dong-Lan; Hou, Yue

    2009-02-01

    To explore the effects of different doses of tyrosine modulation on behavioral performances in open field test of psychological stress rats. The animal model of psychological stress was developed by restraint stress for 21 days. Wistar rats were randomly assigned to five groups (n = 10) as follows: control group (CT), stress control group (SCT), low, medium and high-doses of tyrosine modulation stress groups (SLT, SMT and SIT). The changes of behavioral performances were examined by open-field test. Serum levels of cortisol, norepinephrine and dopamine were also detected. The levels of serum cortisol were all increased obviously in the four stress groups, and their bodyweight gainings were diminished. The behavioral performances of SCT rats in open-field test were changed significantly in contrast to that of CT rats. However, The behavioral performances of SMT and SHT rats were not different from that of CT rats. In addition, the serum levels of norepinephrine and dopamine were downregulated obviously in SCT and SLT groups, and no differences were observed in other groups. Psychological stress can impair body behavioral performances, and moderate tyrosine modulation may improve these abnormal changes. The related mechanisms may be involved with the changes of norepinephrine and dopamine.

  20. Similar reliability and equivalent performance of female and male mice in the open field and water-maze place navigation task

    OpenAIRE

    Fritz, Ann-Kristina; Amrein, Irmgard; Wolfer, David P.

    2017-01-01

    Although most nervous system diseases affect women and men differentially, most behavioral studies using mouse models do not include subjects of both sexes. Many researchers worry that data of female mice may be unreliable due to the estrous cycle. Here, we retrospectively evaluated sex effects on coefficient of variation (CV) in 5,311 mice which had performed the same place navigation protocol in the water-maze and in 4,554 mice tested in the same open field arena. Confidence intervals for C...

  1. Discriminating Between Legitimate and Predatory Open Access Journals: Report from the International Federation for Emergency Medicine Research Committee

    Directory of Open Access Journals (Sweden)

    Bhakti Hansoti

    2016-09-01

    Full Text Available Introduction: Open access (OA medical publishing is growing rapidly. While subscription-based publishing does not charge the author, OA does. This opens the door for “predatory” publishers who take authors’ money but provide no substantial peer review or indexing to truly disseminate research findings. Discriminating between predatory and legitimate OA publishers is difficult. Methods: We searched a number of library indexing databases that were available to us through the University of California, Irvine Libraries for journals in the field of emergency medicine (EM. Using criteria from Jeffrey Beall, University of Colorado librarian and an expert on predatory publishing, and the Research Committee of the International Federation for EM, we categorized EM journals as legitimate or likely predatory. Results: We identified 150 journal titles related to EM from all sources, 55 of which met our criteria for OA (37%, the rest subscription based. Of these 55, 25 (45% were likely to be predatory. We present lists of clearly legitimate OA journals, and, conversely, likely predatory ones. We present criteria a researcher can use to discriminate between the two. We present the indexing profiles of legitimate EM OA journals, to inform the researcher about degree of dissemination of research findings by journal. Conclusion: OA journals are proliferating rapidly. About half in EM are legitimate. The rest take substantial money from unsuspecting, usually junior, researchers and provide no value for true dissemination of findings. Researchers should be educated and aware of scam journals.

  2. Control of the Tomato Leafminer, Tuta absoluta (Lepidoptera: Gelechiidae), in Open-Field Tomatoes by Indigenous Natural Enemies Occurring in Israel.

    Science.gov (United States)

    Shaltiel-Harpaz, Liora; Gerling, Dan; Graph, Shaul; Kedoshim, Hendrika; Azolay, Lotem; Rozenberg, Tamir; Nachache, Yaakov; Steinberg, Shimon; Allouche, Arnon; Alon, Tamar

    2016-02-01

    The tomato leafminer, Tuta absoluta (Meyrick), had established in Israel by 2010, attacking both open-field tomatoes and greenhouse crops.We searched for its natural enemies in open-field tomatoes, and tried to determine their potential for controlling this pest. We surveyed the local natural enemies in open tomato fields and measured their impact on pest populations in an unsprayed field. We assessed the suppressive ability of the dominant hemipteran predator, Nesidiocoris tenuis Reuter, against T. absoluta under controlled laboratory conditions and evaluated the impact of its augmentation on T. absoluta control in open-field tomatoes. We found five natural enemy species:the predator, N. tenuis, two braconids, and two eulophids. Predation accounted for 64.5±9.2% (mean ± SE) of T. absoluta larval mortality, whereas parasitism accounted for 20.96±7.5%. Together, they eliminated the pest population at tomato harvest time. Under controlled conditions, predation by N. tenuis rose from 58 to 72% with increased density of T. absoluta, suggesting positive density dependence. The reduction of T. absoluta (83%) by N. tenuis was higher than that of Bemisia tabaci (32%), suggesting a preference of N. tenuis for T. absoluta. Augmentation of N.tenuis was as effective as conventional treatment insecticide treatment, and plant damage was low and did not seem to affect yield. Results indicate that reduced pesticide use enables indigenous natural enemies, particularly N.tenuis, to successfully control T. absoluta and prevent crop damage in open-field tomatoes.

  3. Standardized UXO Technology Demonstration Site Open Field Scoring Recording Number 231 (Human Factors Applications, Inc.)

    National Research Council Canada - National Science Library

    Overbay, Larry; Robitaille, George

    2005-01-01

    ...) utilizing the APG Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbuy and by the Standardized UXO Technology Demonstration Site Scoring Committee...

  4. Ultralow field emission from thinned, open-ended, and defected carbon nanotubes by using microwave hydrogen plasma processing

    Energy Technology Data Exchange (ETDEWEB)

    Deng, Jian-Hua, E-mail: jhdeng1983@163.com [College of Physics and Materials Science, Tianjin Normal University, Tianjin 300387 (China); Cheng, Lin; Wang, Fan-Jie; Yu, Bin; Li, Guo-Zheng; Li, De-Jun [College of Physics and Materials Science, Tianjin Normal University, Tianjin 300387 (China); Cheng, Guo-An [Key Laboratory of Beam Technology and Material Modification of Ministry of Education, Beijing Normal University, Beijing 100875 (China)

    2015-01-01

    Graphical abstract: Thinned, open-ended, and defected carbon nanotubes were prepared by using hydrogen plasma processing. The processed carbon nanotubes have far better field emission performance than that of the pristine ones. - Highlights: • CVD prepared CNT arrays were processed by microwave hydrogen plasma. • Thinned, open-ended, and defected CNTs were obtained. • Processed CNTs have far better field emission performance than the pristine ones. • Processed CNTs have applicable emission stability after being perfectly aged. - Abstract: Ultralow field emission is achieved from carbon nanotubes (CNTs) by using microwave hydrogen plasma processing. After the processing, typical capped CNT tips are removed, with thinned, open-ended, and defected CNTs left. Structural analyses indicate that the processed CNTs have more SP{sup 3}-hybridized defects as compared to the pristine ones. The morphology of CNTs can be readily controlled by adjusting microwave powers, which change the shape of CNTs by means of hydrogen plasma etching. Processed CNTs with optimal morphology are found to have an ultralow turn-on field of 0.566 V/μm and threshold field of 0.896 V/μm, much better than 0.948 and 1.559 V/μm of the as-grown CNTs, respectively. This improved FE performance is ascribed to the structural changes of CNTs after the processing. The thinned and open-ended shape of CNTs can facilitate electron tunneling through barriers and additionally, the increased defects at tube walls can serve as new active emission sites. Furthermore, our plasma processed CNTs exhibit excellent field emission stability at a large emission current density of 10.36 mA/cm{sup 2} after being perfectly aged, showing promising prospects in applications as high-performance vacuum electron sources.

  5. Review of access, licenses and understandability of open datasets used in hydrology research

    Science.gov (United States)

    Falkenroth, Esa; Arheimer, Berit; Lagerbäck Adolphi, Emma

    2015-04-01

    The amount of open data available for hydrology research is continually growing. In the EU-funded project SWITCH-ON (Sharing Water-related Information to Tackle Changes in the Hydrosphere - for Operational Needs), we are addressing water concerns by exploring and exploiting the untapped potential of these new open data. This work is enabled by many ongoing efforts to facilitate the use of open data. For instance, a number of portals (such as the GEOSS Portal and the INSPIRE community geoportal) provide the means to search for such open data sets and open spatial data services. However, in general, the systematic use of available open data is still fairly uncommon in hydrology research. Factors that limits (re)usability of a data set include: (1) accessibility, (2) understandability and (3) licences. If you cannot access the data set, you cannot use if for research. If you cannot understand the data set you cannot use it for research. Finally, if you are not permitted to use the data, you cannot use it for research. Early on in the project, we sent out a questionnaire to our research partners (SMHI, Universita di Bologna, University of Bristol, Technische Universiteit Delft and Technische Universitaet Wien) to find out what data sets they were planning to use in their experiments. The result was a comprehensive list of useful open data sets. Later, this list of data sets was extended with additional information on data sets for planned commercial water-information products and services. With the list of 50 common data sets as a starting point, we reviewed issues related to access, understandability and licence conditions. Regarding access to data sets, a majority of data sets were available through direct internet download via some well-known transfer protocol such as ftp or http. However, several data sets were found to be inaccessible due to server downtime, incorrect links or problems with the host database management system. One possible explanation for this

  6. Information field for historical research

    Directory of Open Access Journals (Sweden)

    Sviatets, Yu. A.

    2017-09-01

    Full Text Available The article analyzes the main information collision of historical knowledge, which consists in physical inaccessibility of events and phenomena of the past as an object of historical science for a historian as an investigator. The aim of the research is to formulate and discuss a working hypothesis about the information field of historical science. The article provides an analytical background on the main ideas and approaches in the field of modern information field theory. The author carries out the projection of the main provisions of the information field theory on historical research. It is shown that the information field is a really existing information carrier that provides its acquisition, transportation, storage and visualization, as well as provides information and knowledge recorded in various forms, realizes cultural communications. One of the manifestations of such a culture is the sign systems, which determine certain contexts. Signs are characterized by polysemy. Despite artificial origin, semiotic reality is objective. Simultaneously, signs provide intellectual activity of people. Mental signs in the historical process of use by society acquire additional meanings, generating new symbols. Polysemy shapes the problem of epistemological uncertainty of two stages – identifying the problem and solving it. Historians as researchers resort to cognitive models, which, thanks to the translational function, ensure the transfer of information from the known to the unknown. One of the explanations of polysemy is the theory of conceptual integration, according to which the structures of the original mental spaces are projected onto a new, constructed, mental space – blend. This is the result of a personʼs intellectual ability to create new meanings on the basis of the available ones. Since signs and symbols are multi-valued, they form a multiplicity of retrospective scenarios of historical research at the stage of problem formulation

  7. Predatory Open Access in Rehabilitation.

    Science.gov (United States)

    Manca, Andrea; Martinez, Gianluca; Cugusi, Lucia; Dragone, Daniele; Mercuro, Giuseppe; Deriu, Franca

    2017-05-01

    Increasingly scholars and researchers are being solicited by predatory open access journals seeking manuscript submissions and abusing the author-pays model by charging authors with publishing fees without any or proper peer review. Such questionable editorial practices are threatening the reputation and credibility of scholarly publishing. To date, no investigation has been conducted on this phenomenon in the field of rehabilitation. This study attempts to identify specific predatory journals operating in this field to quantify the phenomenon and its geographic distribution. Beall's List has been used to this end which, although not perfect, is a comprehensive and up-to-date report of predatory publishers. Of the 1113 publishers on the list, 59 journals were identified, for a total of 5610 published articles. The median number of articles published by each journal was 21, and the median amount of article processing charges was $499. Only 1 out of 59 journals was included in the Directory of Open Access Journals, whereas 7 (12%) were indexed by PubMed. Most of the publishers were based in India (36%) followed by the United States (25%) and Pakistan (5%), and 25% were without a verifiable address. The data indicate that the threat of predatory publishing in rehabilitation is real. Physiatrists, physiotherapists, researchers, and academics operating in this field are advised to use the tools available to recognize predatory practices before considering publishing in open access journals. Copyright © 2017 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  8. The effects of gonadectomy and binge-like ethanol exposure during adolescence on open field behaviour in adult male rats.

    Science.gov (United States)

    Yan, Wensheng; Kang, Jie; Zhang, Guoliang; Li, Shuangcheng; Kang, Yunxiao; Wang, Lei; Shi, Geming

    2015-09-14

    Binge drinking ethanol exposure during adolescence can lead to long-term neurobehavioural damage. It is not known whether the pubertal surge in testosterone that occurs during adolescence might impact the neurobehavioural effects of early ethanol exposure in adult animals. We examined this hypothesis by performing sham or gonadectomy surgeries on Sprague-Dawley rats around postnatal day (P) 23. From P28-65,the rats were administered 3.0g/kg ethanol using a binge-like model of exposure. Dependent measurements included tests of open field behaviour, blood ethanol concentrations, and testosterone levels. As adults, significant decreases in open field activity were observed in the GX rats. The open field behaviour of the GX rats was restored after testosterone administration. Binge-like ethanol exposure altered most of the parameters of the open field behaviour, suggestive of alcohol-induced anxiety, but rats treated with alcohol in combination with gonadectomy showed less motor behaviour and grooming behaviour and an increase in immobility, suggesting ethanol-induced depression. These results indicated that testosterone is required for ethanol-induced behavioural changes and that testicular hormones are potent stimulators of ethanol-induced behaviours. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  9. RESEARCH OF USING OPEN DOUBLE T BEAMS FOR SPANS IN FLOATING BRIDGES

    Directory of Open Access Journals (Sweden)

    YU. M. Gorbatiuk

    2014-03-01

    Full Text Available Purpose. The publication presents the results of calculations of spans for floating bridges with open double T beams. The purpose of research is to analyze the suitability of spans from open double T beams for floating bridges with minimum weight under loads, which is provided by standards for modern floating bridges designing. Methodology. Comparative method, analytical calculation methods (influence lines methodology, strength calculations, endurance, maximum shear stress are used in this paper. Findings. Current loads for bridges calculations are 75% more than those, for which the spans of floating bridge from NZhM-56 property are designed. The use of open double T beams that is formed with double T beam no. 70 (the height of the open one is 104 cm reduces the cross sectional area in a weakened spot, but virtually it does not influence the strength and durability of the material. The use of open double T beams for spans of floating bridges saves up to 22 % of metal that means one in five spans will made of saved metal. Savings on each spans, such as CRP, will be 33.6 - 263 thous. grn. (considering the price of 1 ton of final product 29 thous. grn.. Originality. Research allows making next step in material saving and use of open double T beams for spans in the whole. Practical value. The obtained results give us possibility to make a number of conclusions that allow us to become more familiar and more practical with the use of open double T beams for spans of floating bridges.

  10. Pollination deficit in open-field tomato crops (Solanum lycopersicum L., Solanaceae in Rio de Janeiro state, Southeast Brazil

    Directory of Open Access Journals (Sweden)

    Maria Cristina Gaglianone

    2013-10-01

    Full Text Available More than 70% of world’s crops benefit from biotic pollination, and bees are their main pollinators. Despite the fact that some of these insects have been broadly studied, understanding the interactions between plant crops and their pollinators with a local scale approach is necessary when aiming to apply proper protective and management measures to pollinators and their respective crops. In this context, we analyzed the pollination status of open-field tomato crops (Solanum lycopersicum L., regarding fruit-set, visitation rate and the quality of fruits. We recorded the formation of fruits through spontaneous self-pollination and open-pollination, and the occurrence of pollinators in 24 areas of open-field tomato crops. We performed experiments of apomixis, spontaneous self-pollination, manual cross pollination and supplemental cross pollination (simulating the pollinator behavior in a greenhouse. The fruit quality was evaluated according to circumference, weight, volume and number of seeds. Higher production of fruits after open-pollination compared to spontaneous self-pollination indicates the importance of pollinators to increment productivity of S. lycopersicum in the study area. The circumference and the number of seeds from tomatoes of the greenhouse plantation did not differ between spontaneous self-pollination and the manual cross pollination. In the open-field crops the number of seeds was higher for fruits resulting from open-pollination. Our results indicate that the importance of bees is mainly related to the increase in fruit production, thus incrementing the productivity of tomato crops.

  11. Pollination deficit in open-field tomato crops (Solanum lycopersicum L., Solanaceae in Rio de Janeiro state, Southeast Brazil

    Directory of Open Access Journals (Sweden)

    Mariana Scaramussa Deprá

    2014-02-01

    Full Text Available More than 70% of world’s crops benefit from biotic pollination, and bees are their main pollinators. Despite the fact that some of these insects have been broadly studied, understanding the interactions between plant crops and their pollinators with a local scale approach is necessary when aiming to apply proper protective and management measures to pollinators and their respective crops. In this context, we analyzed the pollination status of open-field tomato crops (Solanum lycopersicum L., regarding fruit-set, visitation rate and the quality of fruits. We recorded the formation of fruits through spontaneous self-pollination and open-pollination, and the occurrence of pollinators in 24 areas of open-field tomato crops. We performed experiments of apomixis, spontaneous self-pollination, manual cross pollination and supplemental cross pollination (simulating the pollinator behavior in a greenhouse. The fruit quality was evaluated according to circumference, weight, volume and number of seeds. Higher production of fruits after open-pollination compared to spontaneous self-pollination indicates the importance of pollinators to increment productivity of S. lycopersicum in the study area. The circumference and the number of seeds from tomatoes of the greenhouse plantation did not differ between spontaneous self-pollination and the manual cross pollination. In the open-field crops the number of seeds was higher for fruits resulting from open-pollination. Our results indicate that the importance of bees is mainly related to the increase in fruit production, thus incrementing the productivity of tomato crops.

  12. The stimulatory effects of caffeine with oseltamivir (Tamiflu) on light-dark behavior and open-field behavior in mice.

    Science.gov (United States)

    Uchiyama, Hidemori; Toda, Akihisa; Imoto, Masumi; Nishimura, Satoko; Kuroki, Hiroaki; Soeda, Shinji; Shimeno, Hiroshi; Watanabe, Shigenori; Eyanagi, Reiko

    2010-01-22

    Abnormal behaviors and death associated with the use of oseltamivir (Tamiflu) have emerged as a major issue in influenza patients taking the drug. Here, we investigated the mechanisms underlying the effects of oseltamivir on the behavior of mice using light-dark and open-field preference tests. Oseltamivir (75 and 150 mg/kg, intraperitoneally (i.p.)) alone affected neither time spent in the open area in the light-dark preference test nor ambulation in the open-field test at 2h post-injection. However, a non-selective adenosine A(1)/A(2) receptor antagonist, caffeine (10mg/kg, i.p.) in combination with oseltamivir (150 mg/kg, i.p.) increased time spent in the open area in the light-dark preference test. This enhancement was not inhibited by a benzodiazepine receptor antagonist, flumazenil (10-20mg/kg, subcutaneously (s.c.)). Enhancement of ambulation in the open-field test was also observed when caffeine (10mg/kg, i.p.) was combined with oseltamivir (150 mg/kg, i.p.). This enhancement was inhibited by a dopamine D(2) receptor antagonist, haloperidol (0.1mg/kg, s.c.). Furthermore, an adenosine A(2) receptor antagonist, SCH58261 (3mg/kg, i.p.) in combination with oseltamivir (150 mg/kg, i.p.) increased ambulation in the open-field test, while an adenosine A(1) receptor antagonist, DPCPX (1-3mg/kg, i.p.) did not. These findings suggest that the actions of oseltamivir may involve the dopamine and adenosine systems. Our findings suggest that due to the interaction between central blockade of adenosine A(2) receptors by caffeine, and oseltamivir-induced behavioral changes, patients being treated with oseltamivir should be closely monitored. (c) 2009 Elsevier Ireland Ltd. All rights reserved.

  13. Open3DQSAR

    DEFF Research Database (Denmark)

    Tosco, Paolo; Balle, Thomas

    2011-01-01

    Description Open3DQSAR is an open-source tool aimed at pharmacophore exploration by high-throughput chemometric analysis of molecular interaction fields (MIFs). Open3DQSAR can generate steric potential, electron density and MM/QM electrostatic potential fields; furthermore, it can import GRIDKONT...... binary files produced by GRID and CoMFA/CoMSIA fields (exported from SYBYL with the aid of a small SPL script). Subsequently, Open3DQSAR performs fast, automated PLS chemometric analysis of MIFs allowing to quickly generate and challenge the predictivity of many 3D-QSAR models using different training...... integration with OpenBabel, PyMOL, gnuplot •Multi-threaded computation of MIFs (both MM and QM); support for MMFF94 and GAFF force-fields with automated assignment of atom types to the imported molecular structures •Comprehensive output, including SDF molecular databases, 3D maps and many different plots...

  14. Potential risk levels of invasive Neoleucinodes elegantalis (small tomato borer) in areas optimal for open-field Solanum lycopersicum (tomato) cultivation in the present and under predicted climate change.

    Science.gov (United States)

    da Silva, Ricardo Siqueira; Kumar, Lalit; Shabani, Farzin; Picanço, Marcelo Coutinho

    2017-03-01

    Neoleucinodes elegantalis is one of the major insect pests of Solanum lycopersicum. Currently, N. elegantalis is present only in America and the Caribbean, and is a threat in the world's largest S. lycopersicum-producing countries. In terms of potential impact on agriculture, the impact of climate change on insect invasions must be a concern. At present, no research exists regarding the effects of climatic change on the risk level of N. elegantalis. The purpose of this study was to develop a model for S. lycopersicum and N. elegantalis, utilizing CLIMEX to determine risk levels of N. elegantalis in open-field S. lycopersicum cultivation in the present and under projected climate change, using the global climate model CSIRO-Mk3.0. Large areas are projected to be suitable for N. elegantalis and optimal for open-field S. lycopersicum cultivation at the present time. However, in the future these areas will become unsuitable for both species. Conversely, other regions in the future may become optimal for open-field S. lycopersicum cultivation, with a varying risk level for N. elegantalis. The risk level results presented here provide a useful tool to design strategies to prevent the introduction and establishment of N. elegantalis in open-field S. lycopersicum cultivation. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

  15. Opening the Pandora's box of quantum spinor fields

    Energy Technology Data Exchange (ETDEWEB)

    Bonora, L. [International School for Advanced Studies-SISSA, Trieste (Italy); Silva, J.M.H. da [Universidade Estadual Paulista-UNESP, Departamento de Fisica e Quimica, Guaratingueta, SP (Brazil); Rocha, R. da [Universidade Federal do ABC-UFABC, Centro de Matematica, Computacao e Cognicao, Santo Andre (Brazil)

    2018-02-15

    Lounesto's classification of spinors is a comprehensive and exhaustive algorithm that, based on the bilinears covariants, discloses the possibility of a large variety of spinors, comprising regular and singular spinors and their unexpected applications in physics and including the cases of Dirac, Weyl, and Majorana as very particular spinor fields. In this paper we pose the problem of an analogous classification in the framework of second quantization. We first discuss in general the nature of the problem. Then we start the analysis of two basic bilinear covariants, the scalar and pseudoscalar, in the second quantized setup, with expressions applicable to the quantum field theory extended to all types of spinors. One can see that an ampler set of possibilities opens up with respect to the classical case. A quantum reconstruction algorithm is also proposed. The Feynman propagator is extended for spinors in all classes. (orig.)

  16. Automatic analysis of altered gait in arylsulphatase A-deficient mice in the open field.

    Science.gov (United States)

    Leroy, Toon; Stroobants, Stijn; Aerts, Jean-Marie; D'Hooge, Rudi; Berckmans, Daniel

    2009-08-01

    In current research with laboratory animals, observing their dynamic behavior or locomotion is a labor-intensive task. Automatic continuous monitoring can provide quantitative data on each animal's condition and coordination ability. The objective of the present work is to develop an automated mouse observation system integrated with a conventional open-field test for motor function evaluation. Data were acquired from 86 mice having a targeted disruption of the arylsulphatase A (ASA) gene and having lowered coordinated locomotion abilities as a symptom. The mice used were 36 heterozygotes (12 females) and 50 knockout mice (30 females) at the age of 6 months. The mice were placed one at a time into the test setup, which consisted of a Plexiglas cage (53x34.5x26 cm) and two fluorescent bulbs for proper illumination. The transparent cage allowed images to be captured from underneath the cage, so image information could be obtained about the dynamic variation of the positions of the limbs of the mice for gait reconstruction. Every mouse was recorded for 10 min. Background subtraction and color filtering were used to measure and calculate image features, which are variables that contain crucial information, such as the mouse's position, orientation, body outline, and possible locations for the mouse's paws. A set of heuristic rules was used to prune implausible paw features and label the remaining ones as front/hind and left/right. After we had pruned the implausible paw features, the paw features that were consistent over subsequent images were matched to footprints. Finally, from the measured footprint sequence, eight parameters were calculated in order to quantify the gait of the mouse. This automatic observation technique can be integrated with a regular open-field test, where the trajectory and motor function of a free-moving mouse are measured simultaneously.

  17. A model of the open magnetosphere. [with field configuration based on Chapman-Ferraro theory

    Science.gov (United States)

    Kan, J. R.; Akasofu, S.-I.

    1974-01-01

    The Chapman-Ferraro image method is extended to construct an idealized model of the open magnetosphere that responds to a change of the interplanetary field direction as well as to a change of the field magnitude or of the solar wind momentum flux. The magnetopause of the present model is an infinite plane surface having a normal field component distribution that is consistent with the merging theory. An upper limit on the inward displacement of the magnetopause following a southward turning of the interplanetary field is obtained. The results are in fair agreement with a single event reported by Aubry et al. (1971). The model determines the field configuration and the total magnetic flux connecting the magnetosphere to interplanetary space.

  18. Modeling and measuring sound propagation of hooded crow calls in open field habitats

    DEFF Research Database (Denmark)

    Jensen, Kenneth Kragh; Larsen, Ole Næsbye; Attenborough, Keith

    representative of crow territorial communication and taking into account ground effect and air turbulence, we predict an optimal transmission frequency range between 0,5-1.6 kHz. In a natural open field crow habitat we measure, with sender and receiver heights of 2.8 m and transmission distances up to 320 m...

  19. Inability of Open-Field Autorefraction to Eliminate Accommodation in Preschoolers.

    Science.gov (United States)

    Kara, Caner; Petriçli, İkbal Seza

    2017-09-01

    To evaluate the effectiveness of the Shin-Nippon NVision-K 5001 autorefractometer (Rexxam Co. Ltd., Osaka, Japan) (also branded as the Grand Seiko WR-5100K; Grand Seiko Co. Ltd., Hiroshima, Japan) based on the open-field refractometry principle in refractive measurements of preschool children and to determine its ability to eliminate accommodation adequately. The refractive results of 114 preschool children who presented to the ophthalmology outpatient department for screening were evaluated. The measurements were obtained before and after cycloplegia with the Shin-Nippon NVision-K 5001 autorefractometer and after cycloplegia with retinoscopy, which is the gold standard. The results underwent vectorial transformation to produce the spherical equivalent (M) and two Jackson cross-cylinder (J0 and J45) values. All results were then subjected to statistical analysis. The difference between the measurements was evaluated with repeated measures analysis of variance. Included in the study were 106 preschool children (51 boys and 55 girls). The mean age was 5.3 ± 0.9 years (range: 3 to 6 years). Although statistically significantly more myopic results were obtained with non-cycloplegic measurements using the Shin-Nippon NVision-K 5001 autorefractometer (P .05). Cycloplegic J0 measurements were significantly lower (P .05). The Shin-Nippon NVision-K 5001/Grand Seiko WR-5100K open-field autorefractometer seems to be inadequate in eliminating accommodation in childhood. Measurements under cycloplegia continue to be the best method to ensure accurate results. [J Pediatr Ophthalmol Strabismus. 2017;54(5):311-318.]. Copyright 2017, SLACK Incorporated.

  20. Open Data in Global Environmental Research: Findings from the Community

    Energy Technology Data Exchange (ETDEWEB)

    Van Honk, J.; Calero-Medina, C.; Costas, R.

    2016-07-01

    This paper presents findings from the Belmont Forum’s survey on Open Data which targeted the global environmental research and data infrastructure community (Schmidt, Gemeinholzer & Treloar, 2016). It highlights users’ perceptions of the term “open data”, expectations of infrastructure functionalities, and barriers and enablers for the sharing of data. A wide range of good practice examples was pointed out by the respondents which demonstrates a substantial uptake of data sharing through e-infrastructures and a further need for enhancement and consolidation. Among all policy responses, funder policies seem to be the most important motivator. This supports the conclusion that stronger mandates will strengthen the case for data sharing. The Belmont Forum, a group of high-level representatives from major funding agencies across the globe, coordinates funding for collaborative research to address the challenges and opportunities of global environmental change. In particular, the E-Infrastructure and Data Management Collaborative Research Action has brought together domain scientists, computer and information scientists, legal scholars, social scientists, and other experts from more than 14 countries to establish recommendations on how the Belmont Forum can implement a more coordinated, holistic, and sustainable approach to the funding and support of global environmental change research. (Author)

  1. Kepler red-clump stars in the field and in open clusters

    DEFF Research Database (Denmark)

    Bossini, D.; Miglio, A.; Salaris, M.

    2017-01-01

    Convective mixing in helium-core-burning (HeCB) stars is one of the outstanding issues in stellar modelling. The precise asteroseismic measurements of gravity-mode period spacing (Delta Pi(1)) have opened the door to detailed studies of the near-core structure of such stars, which had not been...... possible before. Here, we provide stringent tests of various core-mixing scenarios against the largely unbiased population of red-clump stars belonging to the old-open clusters monitored by Kepler, and by coupling the updated precise inference on Delta Pi(1) in thousands of field stars with spectroscopic...... constraints. We find that models with moderate overshooting successfully reproduce the range observed of Delta Pi(1) in clusters. In particular, we show that there is no evidence for the need to extend the size of the adiabatically stratified core, at least at the beginning of the HeCB phase. This conclusion...

  2. Subchronic Oral Bromocriptine Methanesulfonate Enhances Open Field Novelty-Induced Behavior and Spatial Memory in Male Swiss Albino Mice

    OpenAIRE

    Onaolapo, Olakunle James; Onaolapo, Adejoke Yetunde

    2012-01-01

    This study set out to assess the neurobehavioral effects of subchronic, oral bromocriptine methanesulfonate using the open field and the Y-maze in healthy male mice. Sixty adult Swiss albino mice were assigned into three groups. Controls received normal saline, while test groups received bromocriptine methanesulfonate at 2.5 and 5 mg/kg/day, respectively, for a period of 21 days. Neurobehavioral tests were carried out on days 1 and 21 after administration. Open field assessment on day 1 after...

  3. The effects of conducting authentic field-geology research on high school students' understanding of the nature of science, and their views of themselves as research scientists

    Science.gov (United States)

    Millette, Patricia M.

    Authentic field geology research is a inquiry method that encourages students to interact more with their local environment, and by solving genuine puzzles, begin to increase their intuitive understanding of the nature and processes of science. The goal of the current study was to determine if conducting authentic field research and giving high school students the opportunity to present findings to adult audiences outside of the school setting 1) enhances students' understanding of the nature of science, and 2) affects students views of themselves as researchers. To accomplish this, ninth-grade students from a public school in northern New England engaged in a community-initiated glacial geology problem, completed a field research investigation, and presented their findings at several professional conferences. Following the completion of this student-centered field research, I investigated its effects by using a mixed methods approach consisting of qualitative and quantitative data from two sources. These included selected questions from an open-response survey (VNOS-c), and interviews that were conducted with fifteen of the students of different ages and genders. Findings show that conducting original field research seems to have a positive influence on these students' understanding of the NOS as well as the processes of science. Many of the students reported feelings of accomplishment, acceptance of responsibility for the investigation, a sense of their authentic contribution to the body of scientific knowledge in the world, and becoming scientists. This type of authentic field investigation is significant because recent reforms in earth-science education stress the importance of students learning about the nature and processes of scientific knowledge along with science content.

  4. 78 FR 70917 - Emerging Technology and Research Advisory Committee; Notice of Open Meeting

    Science.gov (United States)

    2013-11-27

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security Emerging Technology and Research Advisory Committee; Notice of Open Meeting The Emerging Technology and Research Advisory Committee (ETRAC) will meet... Secretary for Export Administration on emerging technology and research activities, including those related...

  5. 77 FR 39209 - Emerging Technology and Research Advisory Committee; Notice of Open Meeting

    Science.gov (United States)

    2012-07-02

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security Emerging Technology and Research Advisory Committee; Notice of Open Meeting The Emerging Technology and Research Advisory Committee (ETRAC) will meet... Secretary for Export Administration on emerging technology and research activities, including those related...

  6. 77 FR 59374 - Emerging Technology and Research Advisory Committee; Notice of Open Meeting

    Science.gov (United States)

    2012-09-27

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security Emerging Technology and Research Advisory Committee; Notice of Open Meeting The Emerging Technology and Research Advisory Committee (ETRAC) will meet... Secretary for Export Administration on emerging technology and research activities, including those related...

  7. Monosodium glutamate-associated alterations in open field, anxiety-related and conditioned place preference behaviours in mice.

    Science.gov (United States)

    Onaolapo, Olakunle James; Aremu, Olaleye Samuel; Onaolapo, Adejoke Yetunde

    2017-07-01

    The present study investigated changes in behaviour associated with oral monosodium glutamate (a flavouring agent), using the open field, elevated plus maze and conditioned place preference (CPP) paradigms, respectively. Mice were assigned to two groups for CPP [monosodium glutamate (MSG)-naïve (n = 40) and MSG-pretreated (n = 40)] and two groups for open field (OF) and elevated plus maze (EPM) tests [n = 40 each], respectively. Animals in respective groups were then divided into four subgroups (n = 10) (vehicle or MSG (80, 160 and 320 mg/kg)). MSG-naïve mice were observed in the CPP box in three phases (pre-conditioning, conditioning and post-conditioning). Mice were conditioned to MSG or an equivalent volume of saline. The MSG pretreatment group received vehicle or respective doses of MSG daily for 21 days, prior to conditioning. Mice in the OF or EPM groups received vehicle or doses of MSG (orally) for 21 days, at 10 ml/kg. Open field or EPM behaviours were assessed on days 1 and 21. At the end of the experiments, mice in the OF groups were sacrificed and brain homogenates used to assay glutamate and glutamine. Results showed that administration of MSG was associated with a decrease in rearing, dose-related mixed horizontal locomotor, grooming and anxiety-related response and an increase in brain glutamate/glutamine levels. Following exposure to the CPP paradigm, MSG-naïve and MSG-pretreated mice both showed 'drug-paired' chamber preference. The study concluded that MSG (at the administered doses) was associated with changes in open field activities, anxiety-related behaviours and brain glutamate/glutamine levels; its ingestion also probably leads to a stimulation of the brain reward system.

  8. GROWTH AND PRODUCTION OF KIWANO IN THE OPEN FIELD IN THE SOUTH OF WESTERN SIBERIA

    Directory of Open Access Journals (Sweden)

    N. B. Naumova

    2016-01-01

    Full Text Available Kiwano plants, or horned cucumber (Cucumis metuliferus E. Mey ex Naudin was grown in the open field in several experimental plots in the south of West Siberia (54,95025 N, 83,09763 E. Fruits production was correlated with night air temperature sum and soil organic matter content, reaching the maximum of 2.7 kg (fresh phytomass per plant. Fruit size and some basic juice characteristics were similar to those of kiwano fruits grown elsewhere in the world. The vegetative phytomass grown was correlated with day air temperature sum, being practically independent of soil chemical properties. Thus kiwano can be recommended as a crop to be grown in the open field in the south of West Siberia and other regions of Russia with similar soil and environmental conditions.

  9. Open access for operational research publications from low- and middle-income countries: who pays?

    Science.gov (United States)

    Zachariah, R; Kumar, A M V; Reid, A J; Van den Bergh, R; Isaakidis, P; Draguez, B; Delaunois, P; Nagaraja, S B; Ramsay, A; Reeder, J C; Denisiuk, O; Ali, E; Khogali, M; Hinderaker, S G; Kosgei, R J; van Griensven, J; Quaglio, G L; Maher, D; Billo, N E; Terry, R F; Harries, A D

    2014-09-21

    Open-access journal publications aim to ensure that new knowledge is widely disseminated and made freely accessible in a timely manner so that it can be used to improve people's health, particularly those in low- and middle-income countries. In this paper, we briefly explain the differences between closed- and open-access journals, including the evolving idea of the 'open-access spectrum'. We highlight the potential benefits of supporting open access for operational research, and discuss the conundrum and ways forward as regards who pays for open access.

  10. A model to relate wind tunnel measurements to open field odorant emissions from liquid area sources

    Science.gov (United States)

    Lucernoni, F.; Capelli, L.; Busini, V.; Sironi, S.

    2017-05-01

    Waste Water Treatment Plants are known to have significant emissions of several pollutants and odorants causing nuisance to the near-living population. One of the purposes of the present work is to study a suitable model to evaluate odour emissions from liquid passive area sources. First, the models describing volatilization under a forced convection regime inside a wind tunnel device, which is the sampling device that typically used for sampling on liquid area sources, were investigated. In order to relate the fluid dynamic conditions inside the hood to the open field and inside the hood a thorough study of the models capable of describing the volatilization phenomena of the odorous compounds from liquid pools was performed and several different models were evaluated for the open field emission. By means of experimental tests involving pure liquid acetone and pure liquid butanone, it was verified that the model more suitable to describe precisely the volatilization inside the sampling hood is the model for the emission from a single flat plate in forced convection and laminar regime, with a fluid dynamic boundary layer fully developed and a mass transfer boundary layer not fully developed. The proportionality coefficient for the model was re-evaluated in order to account for the specific characteristics of the adopted wind tunnel device, and then the model was related with the selected model for the open field thereby computing the wind speed at 10 m that would cause the same emission that is estimated from the wind tunnel measurement furthermore, the field of application of the proposed model was clearly defined for the considered models during the project, discussing the two different kinds of compounds commonly found in emissive liquid pools or liquid spills, i.e. gas phase controlled and liquid phase controlled compounds. Lastly, a discussion is presented comparing the presented approach for emission rates recalculation in the field, with other approaches

  11. Afraid of Scooping – Case Study on Researcher Strategies against Fear of Scooping in the Context of Open Science

    Directory of Open Access Journals (Sweden)

    Heidi Laine

    2017-06-01

    Full Text Available The risk of scooping is often used as a counter argument for open science, especially open data. In this case study I have examined openness strategies, practices and attitudes in two open collaboration research projects created by Finnish researchers, in order to understand what made them resistant to the fear of scooping. The radically open approach of the projects includes open by default funding proposals, co-authorship and community membership. Primary sources used are interviews of the projects’ founding members. The analysis indicates that openness requires trust in close peers, but not necessarily in research community or society at large. Based on the case study evidence, focusing on intrinsic goals, like new knowledge and bringing about ethical reform, instead of external goals such as publications, supports openness. Understanding fundaments of science, philosophy of science and research ethics, can also have a beneficial effect on willingness to share. Whether there are aspects in open sharing that makes it seem riskier from the point of view of certain demographical groups within research community, such as women, could be worth closer inspection.

  12. Perspectives in understanding open access to research data - infrastructure and technology challenges

    Science.gov (United States)

    Bigagli, Lorenzo; Sondervan, Jeroen

    2014-05-01

    The Policy RECommendations for Open Access to Research Data in Europe (RECODE) project, started in February 2013 with a duration of two years, has the objective to identify a series of targeted and over-arching policy recommendations for Open Access to European research data, based on existing good practice and addressing such hindering factors as stakeholder fragmentation, technical and infrastructural issues, ethical and legal issues, and financial and institutional policies. In this work we focus on the technical and infrastructural aspect, where by "infrastructure" we mean the technological assets (hardware and software), the human resources, and all the policies, processes, procedures and training for managing and supporting its continuous operation and evolution. The context targeted by RECODE includes heterogeneous networks, initiatives, projects and communities that are fragmented by discipline, geography, stakeholder category (publishers, academics, repositories, etc.) as well as other boundaries. Many of these organizations are already addressing key technical and infrastructural barriers to Open Access to research data. Such barriers may include: lack of automatic mechanisms for policy enforcement, lack of metadata and data models supporting open access, obsolescence of infrastructures, scarce awareness about new technological solutions, lack of training and/or expertise on IT and semantics aspects. However, these organizations are often heterogeneous and fragmented by discipline, geography, stakeholder category (publishers, academics, repositories, etc.) as well as other boundaries, and often work in isolation, or with limited contact with one another. RECODE has addressed these challenges, and the possible solutions to mitigate them, engaging all the identified stakeholders in a number of ways, including an online questionnaire, case studies interviews, literature review, a workshop. The conclusions have been validated by the RECODE Advisory Board and

  13. LOW-MASS PLANETS IN PROTOPLANETARY DISKS WITH NET VERTICAL MAGNETIC FIELDS: THE PLANETARY WAKE AND GAP OPENING

    Energy Technology Data Exchange (ETDEWEB)

    Zhu Zhaohuan; Stone, James M.; Rafikov, Roman R., E-mail: zhzhu@astro.princeton.edu, E-mail: jstone@astro.princeton.edu, E-mail: rrr@astro.princeton.edu [Department of Astrophysical Sciences, Princeton University, Princeton, NJ, 08544 (United States)

    2013-05-10

    Some regions in protoplanetary disks are turbulent, while some regions are quiescent (e.g. the dead zone). In order to study how planets open gaps in both inviscid hydrodynamic disk (e.g. the dead zone) and the disk subject to magnetorotational instability (MRI), we carried out both shearing box two-dimensional inviscid hydrodynamical simulations and three-dimensional unstratified magnetohydrodynamical (MHD) simulations (having net vertical magnetic fields) with a planet at the box center. We found that, due to the nonlinear wave steepening, even a low mass planet can open gaps in both cases, in contradiction to the ''thermal criterion'' for gap opening. In order to understand if we can represent the MRI turbulent stress with the viscous {alpha} prescription for studying gap opening, we compare gap properties in MRI-turbulent disks to those in viscous HD disks having the same stress, and found that the same mass planet opens a significantly deeper and wider gap in net vertical flux MHD disks than in viscous HD disks. This difference arises due to the efficient magnetic field transport into the gap region in MRI disks, leading to a larger effective {alpha} within the gap. Thus, across the gap, the Maxwell stress profile is smoother than the gap density profile, and a deeper gap is needed for the Maxwell stress gradient to balance the planetary torque density. Comparison with previous results from net toroidal flux/zero flux MHD simulations indicates that the magnetic field geometry plays an important role in the gap opening process. We also found that long-lived density features (termed zonal flows) produced by the MRI can affect planet migration. Overall, our results suggest that gaps can be commonly produced by low mass planets in realistic protoplanetary disks, and caution the use of a constant {alpha}-viscosity to model gaps in protoplanetary disks.

  14. LOW-MASS PLANETS IN PROTOPLANETARY DISKS WITH NET VERTICAL MAGNETIC FIELDS: THE PLANETARY WAKE AND GAP OPENING

    International Nuclear Information System (INIS)

    Zhu Zhaohuan; Stone, James M.; Rafikov, Roman R.

    2013-01-01

    Some regions in protoplanetary disks are turbulent, while some regions are quiescent (e.g. the dead zone). In order to study how planets open gaps in both inviscid hydrodynamic disk (e.g. the dead zone) and the disk subject to magnetorotational instability (MRI), we carried out both shearing box two-dimensional inviscid hydrodynamical simulations and three-dimensional unstratified magnetohydrodynamical (MHD) simulations (having net vertical magnetic fields) with a planet at the box center. We found that, due to the nonlinear wave steepening, even a low mass planet can open gaps in both cases, in contradiction to the ''thermal criterion'' for gap opening. In order to understand if we can represent the MRI turbulent stress with the viscous α prescription for studying gap opening, we compare gap properties in MRI-turbulent disks to those in viscous HD disks having the same stress, and found that the same mass planet opens a significantly deeper and wider gap in net vertical flux MHD disks than in viscous HD disks. This difference arises due to the efficient magnetic field transport into the gap region in MRI disks, leading to a larger effective α within the gap. Thus, across the gap, the Maxwell stress profile is smoother than the gap density profile, and a deeper gap is needed for the Maxwell stress gradient to balance the planetary torque density. Comparison with previous results from net toroidal flux/zero flux MHD simulations indicates that the magnetic field geometry plays an important role in the gap opening process. We also found that long-lived density features (termed zonal flows) produced by the MRI can affect planet migration. Overall, our results suggest that gaps can be commonly produced by low mass planets in realistic protoplanetary disks, and caution the use of a constant α-viscosity to model gaps in protoplanetary disks.

  15. Open Access Articles Have a Greater Research Impact Than Articles Not Freely Available, A review of: Antelman, Kristin. “Do Open-Access Articles Have a Greater Research Impact?” College & Research Libraries 65.5 (Sep. 2004: 372-82.

    Directory of Open Access Journals (Sweden)

    Suzanne P. Lewis

    2006-09-01

    Full Text Available Objective – To ascertain whether open access articles have a greater research impact than articles not freely available, as measured by citations in the ISI Web of Science database. Design – Analysis of mean citation rates of a sample population of journal articles across four disciplines. Setting – Journal literature across the disciplines of philosophy, political science, mathematics, and electrical and electronic engineering. Subjects – A sample of 2,017 articles across the four disciplines published between 2001 and 2002 (for political science, mathematics, and electrical and electronic engineering and between 1999 and 2000 (for philosophy. Methods – A systematic presample of articles for each of the disciplines was taken to calculate the necessary sample sizes. Based on this calculation, articles were sourced from ten leading journals in each discipline. The leading journals in political science, mathematics, and electrical and electronic engineering were defined by ISI’s Journal Citation Reports for 2002. The ten leading philosophy journals were selected using a combination of other methods. Once the sample population had been identified, each article title and the number of citations to each article (in the ISI Web of Science database were recorded. Then the article title was searched in Google and if any freely available full text version was found, the article was classified as open access. The mean citation rate for open access and non‐open access articles in each discipline was identified, and the percentage difference between the means was calculated. Main results – The four disciplines represented a range of open access uptake: 17% of articles in philosophy were open access, 29% in political science, 37% in electrical and electronic engineering, and 69% in mathematics. There was a significant difference in the mean citation rates for open access articles and non‐open access articles in all four disciplines. The

  16. Standardized UXO Technology Demonstration Site, Open Field Scoring Record No. 770. Magnetometer FEREX DLG GPS/Sling

    National Research Council Canada - National Science Library

    Karwatka, Mike; Packer, Bonnie

    2006-01-01

    ...) utilizing the YPG Standardized UXO Technology Demonstration Site open field. Scoring Records have been coordinated by Mike Karwatka and the Standardized UXO Technology Demonstration Site Scoring Committee...

  17. Academic Administrator Influence on Institutional Commitment to Open Access of Scholarly Research

    Science.gov (United States)

    Reinsfelder, Thomas L.

    2012-01-01

    This quantitative study investigated the interrelationships among faculty researchers, publishers, librarians, and academic administrators when dealing with the open access of scholarly research. This study sought to identify the nature of any relationship between the perceived attitudes and actions of academic administrators and an…

  18. Field-oriented control of five-phase induction motor with open-end stator winding

    Directory of Open Access Journals (Sweden)

    Listwan Jacek

    2016-09-01

    Full Text Available The mathematical model of the five-phase squirrel-cage induction motor and the system of the dual five-phase voltage source inverter have been presented. The control methods and control systems of the field-oriented control of the five-phase induction motor with an open-end stator winding are described. The structures of the direct fieldoriented control system (DFOC and the Indirect Field-oriented control system (IFOC with PI controllers in outer and inner control loops are analyzed. A method of space vector modulation used to control the system of the dual five-phase voltage source inverter has been discussed. The results of simulation studies of the field-oriented control methods are presented. Comparative analysis of the simulation results was carried out.

  19. A Bibliometric Mapping of Open Educational Resources

    Directory of Open Access Journals (Sweden)

    Airton Zancanaro

    2015-02-01

    Full Text Available Open educational resources (OER is a topic that has aroused increasing interest by researchers as a powerful contribution to improve the educational system quality and openness, both in face to face and distance education. The goal of this research is to map publications related to OER, dating from 2002 to 2013, and available through the Web of Science and Scopus scientific databases as well as in the OER Knowledge Cloud open repository. Data were used to explore relevant aspects related to the scientific production in OER, such as: (i number of publications per year; (ii most cited publications; (iii authors with higher number of publications; (iv institutions and countries with more publications and (v most referenced bibliography by the authors. The analysis has included 544 papers, written by 843 authors, from 338 institutions, from 61 different countries. Moreover, the analysis has included the publications referenced and the author’s keywords, considering 6,355 different publications and 929 different keywords. Besides presenting a bibliographic mapping of the research on OER, this paper also intends to contribute to consolidate the idea that OER is a promising field for researchers, in line with the spreading of the Open movement.

  20. Hyperactive behaviour in the mouse model of mucopolysaccharidosis IIIB in the open field and home cage environments.

    Science.gov (United States)

    Langford-Smith, A; Malinowska, M; Langford-Smith, K J; Wegrzyn, G; Jones, S; Wynn, R; Wraith, J E; Wilkinson, F L; Bigger, B W

    2011-08-01

    Mucopolysaccharidosis IIIB (MPS IIIB) is a lysosomal storage disorder characterized by severe behavioural disturbances and progressive loss of cognitive and motor function. There is no effective treatment, but behavioural testing is a valuable tool to assess neurodegeneration and the effect of novel therapies in mouse models of disease. Several groups have evaluated behaviour in this model, but the data are inconsistent, often conflicting with patient natural history. We hypothesize that this discrepancy could be due to differences in open field habituation and home cage behaviour. Eight-month-old wild-type and MPS IIIB mice were tested in a 1-h open field test, performed 1.5 h after lights on, and a 24-h home cage behaviour test performed after 24 h of acclimatization. In the 1-h test, MPS IIIB mice were hyperactive, with increased rapid exploratory behaviour and reduced immobility time. No differences in anxiety were seen. Over the course of the test, differences became more pronounced with maximal effects at 1 h. The 24-hour home cage test was less reliable. There was evidence of increased hyperactivity in MPS IIIB mice, however, immobility was also increased, suggesting a level of inconsistency in this test. Performance of open field analysis within 1-2 h after lights on is probably critical to achieving maximal success as MPS IIIB mice have a peak in activity around this time. The open field test effectively identifies hyperactive behaviour in MPS IIIB mice and is a significant tool for evaluating effects of therapy on neurodegeneration. © 2011 The Authors. Genes, Brain and Behavior © 2011 Blackwell Publishing Ltd and International Behavioural and Neural Genetics Society.

  1. Free and Open Source Software for Geospatial in the field of planetary science

    Science.gov (United States)

    Frigeri, A.

    2012-12-01

    Information technology applied to geospatial analyses has spread quickly in the last ten years. The availability of OpenData and data from collaborative mapping projects increased the interest on tools, procedures and methods to handle spatially-related information. Free Open Source Software projects devoted to geospatial data handling are gaining a good success as the use of interoperable formats and protocols allow the user to choose what pipeline of tools and libraries is needed to solve a particular task, adapting the software scene to his specific problem. In particular, the Free Open Source model of development mimics the scientific method very well, and researchers should be naturally encouraged to take part to the development process of these software projects, as this represent a very agile way to interact among several institutions. When it comes to planetary sciences, geospatial Free Open Source Software is gaining a key role in projects that commonly involve different subjects in an international scenario. Very popular software suites for processing scientific mission data (for example, ISIS) and for navigation/planning (SPICE) are being distributed along with the source code and the interaction between user and developer is often very strict, creating a continuum between these two figures. A very widely spread library for handling geospatial data (GDAL) has started to support planetary data from the Planetary Data System, and recent contributions enabled the support to other popular data formats used in planetary science, as the Vicar one. The use of Geographic Information System in planetary science is now diffused, and Free Open Source GIS, open GIS formats and network protocols allow to extend existing tools and methods developed to solve Earth based problems, also to the case of the study of solar system bodies. A day in the working life of a researcher using Free Open Source Software for geospatial will be presented, as well as benefits and

  2. Effects of prenatal ethanol exposure and early experience on home-cage and open-field activity in mice.

    Science.gov (United States)

    Mothes, H K; Opitz, B; Werner, R; Clausing, P

    1996-01-01

    -C57BL/6 mice were intubated from gestational day 14-18 twice daily with 1.58 g/kg ethanol, 4.2 g/kg sucrose, or remained untreated. Offspring of ethanol treated or lab chow control groups were raised either by group-housed dams and weaned on postnatal day (PND) 28 or by individually housed dams and weaned on PND 21. Offspring of the sucrose control group were raised by individually housed dams and weaned on PND 21. Groups did not differ in pup weight or litter size. Offspring were assessed for home-cage activity (PND 36-38) and open-field behavior (PND 40-42). Mice prenatally exposed to ethanol showed increased activity in their home cages, whereas open-field behavior was generally not different from that of control groups. Conversely, different preweaning rearing conditions had affected open-field behavior, but not home-cage activity. In conclusion, home-cage behavior was a sensitive paradigm for detecting hyperactivity subsequent to a relatively low dose of prenatal ethanol in mice, and communal nesting/late weaning vs. individual nesting/ standard weaning may be a useful preweaning environmental manipulation to study possible modifications of prenatal neurobehavioral effects.

  3. Open-Source Software in Computational Research: A Case Study

    Directory of Open Access Journals (Sweden)

    Sreekanth Pannala

    2008-04-01

    Full Text Available A case study of open-source (OS development of the computational research software MFIX, used for multiphase computational fluid dynamics simulations, is presented here. The verification and validation steps required for constructing modern computational software and the advantages of OS development in those steps are discussed. The infrastructure used for enabling the OS development of MFIX is described. The impact of OS development on computational research and education in gas-solids flow, as well as the dissemination of information to other areas such as geophysical and volcanology research, is demonstrated. This study shows that the advantages of OS development were realized in the case of MFIX: verification by many users, which enhances software quality; the use of software as a means for accumulating and exchanging information; the facilitation of peer review of the results of computational research.

  4. Band gap opening of bilayer graphene by F4-TCNQ molecular doping and externally applied electric field.

    Science.gov (United States)

    Tian, Xiaoqing; Xu, Jianbin; Wang, Xiaomu

    2010-09-09

    The band gap opening of bilayer graphene with one side surface adsorption of F4-TCNQ is reported. F4-TCNQ doped bilayer graphene shows p-type semiconductor characteristics. With a F4-TCNQ concentration of 1.3 x 10(-10) mol/cm(2), the charge transfer between each F4-TCNQ molecule and graphene is 0.45e, and the built-in electric field, E(bi), between the graphene layers could reach 0.070 V/A. The charge transfer and band gap opening of the F4-TCNQ-doped graphene can be further modulated by an externally applied electric field (E(ext)). At 0.077 V/A, the gap opening at the Dirac point (K), DeltaE(K) = 306 meV, and the band gap, E(g) = 253 meV, are around 71% and 49% larger than those of the pristine bilayer under the same E(ext).

  5. Improving open access to the results of USGS research (Invited)

    Science.gov (United States)

    Bristol, S.

    2013-12-01

    Since its establishment under the Organic Act of March 3, 1879, the U.S. Geological Survey (USGS) has been committed to classifying and characterizing 'the geological structure, mineral resources, and products of the national domain.' Over time, the pursuit of this mission and understanding the products of the national domain has involved a broad scientific pursuit to understand complex Earth system processes and includes topographic, geologic, biogeographic, and other types of mapping; chemical, physical, hydrological, and biological research; and the application of computer and data science. As science and technology have evolved, classification and characterization of the Nation's natural resources has come to be embodied in digital data of various structure and form. Fundamentally, scientific publications and data produced through research and monitoring form the core of the USGS mission. They are an organizational and national treasure held and provided in trust for the American people and for the global scientific community. The recent memo from the Office of Science and Technology Policy (OSTP) on 'Increasing Access to the Results of Federally Funded Scientific Research' is part of an overall initiative toward open digital government that dovetails well with the USGS mission. The objectives outlined in the memo correspond directly to goals and objectives of the 2007 USGS Science Strategy ('Facing Tomorrow's Challenges--U.S. Geological Survey Science in the Decade 2007-2017') and the recently released Science Strategy Plans across all USGS Mission Areas. The USGS response to the OSTP memo involves reinforcing aspects of the USGS commitment to open and free access to scholarly publications and data along with improvements to some of the underlying technological systems that facilitate search and discovery. These actions also align with the USGS response to the Executive Order on May 9, 2013, entitled 'Making Open and Machine Readable the New Default for

  6. Window opening behaviour: simulations of occupant behaviour in residential buildings using models based on a field survey

    DEFF Research Database (Denmark)

    Valentina, Fabi; Andersen, Rune Korsholm; Corgnati, Stefano Paolo

    2012-01-01

    Window opening behaviour has been shown to have a significant impact on airflow rates and hence energy consumption. Nevertheless, the inhabitant behaviour related to window opening in residential buildings is currently poorly investigated through both field surveys and building energy simulations....... In particular, reliable information regarding user behaviour in residential buildings is crucial for suitable prediction of building performance (energy consumption, indoor environmental quality, etc.). To face this issue, measurements of indoor climate and outdoor environmental parameters and window “opening...... and closing” actions were performed in 15 dwellings from January to August 2008 in Denmark. Probabilistic models of inhabitants’ window “opening and closing” behaviour were developed and implemented in the energy simulation software IDA ICE to improve window opening and closing strategies in simulations...

  7. An Opening to Society: Chances and Prospects of Science, Research and Services.

    Science.gov (United States)

    Heckelmann, Dieter

    1989-01-01

    Describes how the Free University of Berlin (West Germany) has become more open to the public. The Free University has strengthened its cooperation with private companies in research and funding, promoted internal research, and increased its accelerated and continuing education programs in order to improve its image. (LS)

  8. Post-training scopolamine treatment induced maladaptive behavior in open field habituation task in rats.

    Directory of Open Access Journals (Sweden)

    Natalija Popović

    Full Text Available The effects of scopolamine on memory consolidation are controversial and depend on several factors (i.e. site of administration, time of administration and testing, dose, cognitive task, experimental protocol, specie, strain, etc.. Generally, the range dose of systemic administered scopolamine, used in memory consolidation studies, has varied from 0.05 to 50 mg/kg. However, according to the literature, the most frequently used doses of scopolamine efficient on memory consolidation, are 1 and 30 mg/kg, low and high doses, respectively. In open field habituation studies only lower doses of scopolamine were used to test memory consolidation. Therefore, in the present study we compared the effects of low (1 mg/kg and high (30 mg/kg scopolamine dose, on the open field habituation task, in male Wistar rats. Scopolamine was administered immediately after the acquisition task and animals were retested 48 h later on. On the retested day, the ambulation and rearing in the open field decreased in the same manner in all tested groups. In saline- and 1 mg/kg scopolamine-treated animals, the time spent in grooming significantly decreased in the habituation task, while the same parameter significantly increased in animals treated with 30 mg/kg of scopolamine. The defecation rate significantly decreased (control group, maintained (1 mg/kg of scopolamine treated animals or significantly increased (30 mg/kg of scopolamine treated group on retention test. In conclusion, the present data suggest that post-training scopolamine administration does not affect locomotion neither exploration in the habituation to a novel environment, but increases defecation and grooming, two behaviours associated with fearful and stressful situations.

  9. Open access monographs: a humanities research perspective

    Directory of Open Access Journals (Sweden)

    Dr Jim Cheshire

    2014-04-01

    Full Text Available This article discusses the thoughts of a humanities researcher in relation to open access (OA publishing. Digital media have dramatically improved access to historic texts but library e-books are frustrating due to software and loan arrangements. Authors of illustrated books risk losing control of book design, although new media offer opportunities to improve image quality and access. Alfred Tennyson's career shows that authors have been sensitive about the physical form of their work since the Victorian period and ignoring the material significance of the book could make us overlook the fundamental changes that the e-book represents. Monographs retain value as a way of evaluating substantive research projects and those published through the OA process will have great advantages over the commercial e-book. ‘Green’ OA publishing is impractical for humanities scholars and funded ‘gold’ OA publishing is likely to involve a labour-intensive application process.

  10. Open-source tools for data mining.

    Science.gov (United States)

    Zupan, Blaz; Demsar, Janez

    2008-03-01

    With a growing volume of biomedical databases and repositories, the need to develop a set of tools to address their analysis and support knowledge discovery is becoming acute. The data mining community has developed a substantial set of techniques for computational treatment of these data. In this article, we discuss the evolution of open-source toolboxes that data mining researchers and enthusiasts have developed over the span of a few decades and review several currently available open-source data mining suites. The approaches we review are diverse in data mining methods and user interfaces and also demonstrate that the field and its tools are ready to be fully exploited in biomedical research.

  11. Open Letter to Research Councils UK: Rebuttal of ALPSP Critique

    OpenAIRE

    Berners-Lee, Tim; De Roure, Dave; Harnad, Stevan; Shadbolt, Nigel

    2005-01-01

    The Research Councils of the UK (RCUK) propose to require that the authors of all journal articles resulting from RCUK-funded research must make them openly accessible by self-archiving them on the web in order maximise their usage and impact. ALPSP (Association of Learned and Professional Society Publishers) claim that this will have a negative effect on journals, but the only evidence they provide fails to support their claim and all existing evidence is to the contrary: Journal publication...

  12. Enabling Open Science for Health Research: Collaborative Informatics Environment for Learning on Health Outcomes (CIELO).

    Science.gov (United States)

    Payne, Philip; Lele, Omkar; Johnson, Beth; Holve, Erin

    2017-07-31

    There is an emergent and intensive dialogue in the United States with regard to the accessibility, reproducibility, and rigor of health research. This discussion is also closely aligned with the need to identify sustainable ways to expand the national research enterprise and to generate actionable results that can be applied to improve the nation's health. The principles and practices of Open Science offer a promising path to address both goals by facilitating (1) increased transparency of data and methods, which promotes research reproducibility and rigor; and (2) cumulative efficiencies wherein research tools and the output of research are combined to accelerate the delivery of new knowledge in proximal domains, thereby resulting in greater productivity and a reduction in redundant research investments. AcademyHealth's Electronic Data Methods (EDM) Forum implemented a proof-of-concept open science platform for health research called the Collaborative Informatics Environment for Learning on Health Outcomes (CIELO). The EDM Forum conducted a user-centered design process to elucidate important and high-level requirements for creating and sustaining an open science paradigm. By implementing CIELO and engaging a variety of potential users in its public beta testing, the EDM Forum has been able to elucidate a broad range of stakeholder needs and requirements related to the use of an open science platform focused on health research in a variety of "real world" settings. Our initial design and development experience over the course of the CIELO project has provided the basis for a vigorous dialogue between stakeholder community members regarding the capabilities that will add the greatest value to an open science platform for the health research community. A number of important questions around user incentives, sustainability, and scalability will require further community dialogue and agreement. ©Philip Payne, Omkar Lele, Beth Johnson, Erin Holve. Originally published

  13. Pathological behavior of the open-shell restricted self-consistent-field equations

    International Nuclear Information System (INIS)

    Moscardo, F.; Alvarez-Collado, J.R.

    1979-01-01

    The possible solutions of open-shell restricted self-consistent-field equations for a doublet are studied for Li and Na atoms, according to the values of the parameters implied in those equations. A similar behavior, characterized by the presence of several variational solutions is observed in both atoms. Some of these solutions can be assigned to excited configurations. Excitation energies are in good agreement with experimental data. Doublet stability for the solutions obtained has been studied, discussing the saddle-point character present in those solutions associated to excited configurations

  14. Pathological behavior of the open-shell restricted self-consistent-field equations

    Energy Technology Data Exchange (ETDEWEB)

    Moscardo, F.; Alvarez-Collado, J.R.

    1979-02-01

    The possible solutions of open-shell restricted self-consistent-field equations for a doublet are studied for Li and Na atoms, according to the values of the parameters implied in those equations. A similar behavior, characterized by the presence of several variational solutions is observed in both atoms. Some of these solutions can be assigned to excited configurations. Excitation energies are in good agreement with experimental data. Doublet stability for the solutions obtained has been studied, discussing the saddle-point character present in those solutions associated to excited configurations.

  15. Measurements and predictions of hooded crow (Corvus corone cornix) call propagation over open field habitats

    DEFF Research Database (Denmark)

    Jensen, Kenneth Kragh; Larsen, Ole Næsbye; Attenborough, Keith

    2008-01-01

    In a study of hooded crow communication over open fields an excellent correspondence is found between the attenuation spectra predicted by a "turbulence-modified ground effect plus atmospheric absorption" model, and crow call attenuation data. Sound propagation predictions and background noise...

  16. Relations between open-field, elevated plus-maze, and emergence tests as displayed by C57/BL6J and BALB/c mice.

    Science.gov (United States)

    Lalonde, R; Strazielle, C

    2008-06-15

    The relations between open-field, elevated plus-maze, and emergence tests were examined in two strains of mice. In the open-field, C57BL/6J mice had more ambulatory movements and rears but not stereotyped movements relative to BALB/c. In addition, C57BL/6J mice entered more often than BALB/c into enclosed and open arms of the elevated plus-maze. When placed inside a large enclosure, C57BL/6J mice emerged more quickly than BALB/c from a small toy object. In the entire series of mice, ambulation and rears in the open-field were linearly correlated with open and enclosed arm visits in the elevated plus-maze. Ambulatory movements and rears were also correlated with emergence latencies. In contrast, stereotyped movements were correlated with emergence latencies, but not with any elevated plus-maze value. These results specify the extent and limits of association between the three tests.

  17. IMPAIRED LEARNING AND ABNORMAL OPEN-FIELD BEHAVIORS OF RATS AFTER EARLY POSTNATAL ANOXIA AND THE BENEFICIAL EFFECT OF THE CALCIUM-ANTAGONIST NIMODIPINE

    NARCIS (Netherlands)

    NYAKAS, C; MARKEL, E; SCHUURMAN, T; LUITEN, PGM

    1991-01-01

    Perinatal anoxia/hypoxia is considered a serious risk factor for normal brain development. Anoxia induced by repeated asphyxia at 2 and 4 days after birth resulted in a transient hyperactivity in the small open-field, and a behavioural depression in adult open-field activity of male Wistar rats. The

  18. Inspiring the Next Generation of Scientists: Building on 52 Years of Tradition in Diatom Research with Open-Source, Web-Based Collaboration Tools and Online Resources in a Field Course for High School Students

    Science.gov (United States)

    Howard, K. L.; Lee, S. S.

    2015-12-01

    Open-source, web-based forums and online resources can be used to develop a collaborative, active-learning approach for engaging and training students in the scientific process. We used the Diatoms of the United States website as an online resource for diatom taxonomy and developed a Google+ class community to serve as a platform for high school students to learn about research in diatom taxonomy, community ecology and diatom applications to the earth sciences. Ecology and Systematics of Diatoms is a field course that has been taught at the undergraduate and graduate levels at the Iowa Lakeside Lab field station for 52 years, beginning with the Diatom Clinic in 1963. Freshwater diatom education at Lakeside Lab has since evolved into a foundational training course attracting budding diatomists from all over the world, and has grown to include a week-long course for high school students. Successful since 2012, the high school course is now offered for college credit (University of Iowa), and covers methods of diatom specimen collection and preparation, microscopy, identification of diatom genera, diatom ecology, applications of diatom research, and an introduction to data analysis incorporating multivariate statistics (ordination) using the R statistical program, as well as primary scientific literature. During the 2015 course, students contributed to a Google+ class community where they posted images, data, and questions. The web-based platform allowed students to easily share information and to give and receive feedback from both peers and instructors. Students collaborated via the Google+ community and used the Diatoms of the United States website to develop a taxonomic reference for a field-based group research project, simulating how an actual diatom research program would develop a region or project-specific flora harmonized across analysts. Students investigated the taxonomy and ecology of diatom epiphytes on the green alga Cladophora from the littoral zone of

  19. Dissipation and Residues of Pyrethrins in Leaf Lettuce under Greenhouse and Open Field Conditions.

    Science.gov (United States)

    Pan, Lixiang; Feng, Xiaoxiao; Zhang, Hongyan

    2017-07-21

    Pyrethrins are nowadays widely used for prevention and control of insects in leaf lettuce. However, there is a concern about the pesticide residue in leaf lettuce. A reliable analytical method for determination of pyrethrins (pyrethrin-and П, cinerin І and П, and jasmolin І and П) in leaf lettuce was developed by using gas chromatography-mass spectrometry (GC-MS). Recoveries of pyrethrins in leaf lettuce at three spiking levels were 99.4-104.0% with relative standard deviations of 0.9-3.1% ( n = 5). Evaluation of dissipation and final residues of pyrethrins in leaf lettuce were determined at six different locations, including the open field, as well as under greenhouse conditions. The initial concentration of pyrethrins in greenhouse (0.57 mg/kg) was higher than in open field (0.25 mg/kg) and the half-life for pyrethrins disappearance in field lettuce (0.7 days) was less than that greenhouse lettuce (1.1 days). Factors such as rainfall, solar radiation, wind speed, and crop growth rate are likely to have caused these results. The final residue in leaf lettuce was far below the maximum residue limits (MRLs) (1 mg/kg established by the European Union (EU), Australia, Korea, Japan).

  20. Masking release by combined spatial and masker-fluctuation effects in the open sound field.

    Science.gov (United States)

    Middlebrooks, John C

    2017-12-01

    In a complex auditory scene, signals of interest can be distinguished from masking sounds by differences in source location [spatial release from masking (SRM)] and by differences between masker-alone and masker-plus-signal envelopes. This study investigated interactions between those factors in release of masking of 700-Hz tones in an open sound field. Signal and masker sources were colocated in front of the listener, or the signal source was shifted 90° to the side. In Experiment 1, the masker contained a 25-Hz-wide on-signal band plus flanking bands having envelopes that were either mutually uncorrelated or were comodulated. Comodulation masking release (CMR) was largely independent of signal location at a higher masker sound level, but at a lower level CMR was reduced for the lateral signal location. In Experiment 2, a brief signal was positioned at the envelope maximum (peak) or minimum (dip) of a 50-Hz-wide on-signal masker. Masking was released in dip more than in peak conditions only for the 90° signal. Overall, open-field SRM was greater in magnitude than binaural masking release reported in comparable closed-field studies, and envelope-related release was somewhat weaker. Mutual enhancement of masking release by spatial and envelope-related effects tended to increase with increasing masker level.

  1. The Adoption of Open Access Funds Among Canadian Academic Research Libraries, 2008-2012

    Directory of Open Access Journals (Sweden)

    Crystal Hampson

    2014-11-01

    Full Text Available As a result of changes in scholarly communication created by the open access movement, some academic libraries established open access (OA publishing funds. OA funds are monies set aside at an institution to fund open access publishing of the results of scholarly research. OA funds are a recent innovation in the type of services offered by academic libraries. Adoption of an innovation can be examined in the light of established theories of innovation adoption among social systems. To examine academic libraries’ responses to OA publishing charges, this article explores the adoption of OA funds among Canadian academic research libraries from 2008 to 2012 by analyzing results from a series of previously published surveys. The findings are then examined in light of Everett Rogers’ Innovation Diffusion Theory (IDT to consider the question of whether or not OA funds are becoming a standard service in Canadian academic research institutions. Adoption in Canada is briefly compared to that in the United States and United Kingdom. The paper concludes that, as of 2012, OA funds were becoming common but were not a standard service in Canadian academic research libraries and that libraries were actively participating in the development of OA funding models. Given the current Canadian context, the need of researchers for OA publishing support is likely to create pressure for continued adoption of OA funds among Canadian academic research institutions. However, assessment of existing OA funds is needed.

  2. Empirical research on the impact of open-book accounting on organizational performance

    OpenAIRE

    Wei Di; Shiqi Wang

    2017-01-01

    In order to optimize the cost of supply chain and seek cost reduction opportunities, the enterprise discloses the inter-enterprise cost data, which is called as open-book accounting. However, the cooperation between each enterprise across organizational boundaries also involves in the inter-organizational cost management. This paper mainly researches whether the open-book accounting can produce a positive impact on the enterprise performance when the enterprise carries out the inter-organizat...

  3. Should Research Always be OPEN

    OpenAIRE

    Taylor, Mike

    2014-01-01

    "If I have seen further it is by standing on the shoulders of giants", said Isaac Newton. Since the earliest days of science, progress has always been achieved by the free exchange and re-use of ideas. Understanding this, scientists have always leaned in the direction of openness. Science outside of trade secrets and state secrets has a natural tendency to be open. Until recently, the principle barrier to sharing science has been the logistic difficulty of printing and distributing copies...

  4. SmartR: an open-source platform for interactive visual analytics for translational research data.

    Science.gov (United States)

    Herzinger, Sascha; Gu, Wei; Satagopam, Venkata; Eifes, Serge; Rege, Kavita; Barbosa-Silva, Adriano; Schneider, Reinhard

    2017-07-15

    In translational research, efficient knowledge exchange between the different fields of expertise is crucial. An open platform that is capable of storing a multitude of data types such as clinical, pre-clinical or OMICS data combined with strong visual analytical capabilities will significantly accelerate the scientific progress by making data more accessible and hypothesis generation easier. The open data warehouse tranSMART is capable of storing a variety of data types and has a growing user community including both academic institutions and pharmaceutical companies. tranSMART, however, currently lacks interactive and dynamic visual analytics and does not permit any post-processing interaction or exploration. For this reason, we developed SmartR , a plugin for tranSMART, that equips the platform not only with several dynamic visual analytical workflows, but also provides its own framework for the addition of new custom workflows. Modern web technologies such as D3.js or AngularJS were used to build a set of standard visualizations that were heavily improved with dynamic elements. The source code is licensed under the Apache 2.0 License and is freely available on GitHub: https://github.com/transmart/SmartR . reinhard.schneider@uni.lu. Supplementary data are available at Bioinformatics online. © The Author(s) 2017. Published by Oxford University Press.

  5. Automated measurement of spatial preference in the open field test with transmitted lighting.

    Science.gov (United States)

    Kulikov, Alexander V; Tikhonova, Maria A; Kulikov, Victor A

    2008-05-30

    New modification of the open field was designed to improve automation of the test. The main innovations were: (1) transmitted lighting and (2) estimation of probability to find pixels associated with an animal in the selected region of arena as an objective index of spatial preference. Transmitted (inverted) lighting significantly ameliorated the contrast between an animal and arena and allowed to track white animals with similar efficacy as colored ones. Probability as a measure of preference of selected region was mathematically proved and experimentally verified. A good correlation between probability and classic indices of spatial preference (number of region entries and time spent therein) was shown. The algorithm of calculation of probability to find pixels associated with an animal in the selected region was implemented in the EthoStudio software. Significant interstrain differences in locomotion and the central zone preference (index of anxiety) were shown using the inverted lighting and the EthoStudio software in mice of six inbred strains. The effects of arena shape (circle or square) and a novel object presence in the center of arena on the open field behavior in mice were studied.

  6. Open-System Quantum Annealing in Mean-Field Models with Exponential Degeneracy*

    Directory of Open Access Journals (Sweden)

    Kostyantyn Kechedzhi

    2016-05-01

    Full Text Available Real-life quantum computers are inevitably affected by intrinsic noise resulting in dissipative nonunitary dynamics realized by these devices. We consider an open-system quantum annealing algorithm optimized for such a realistic analog quantum device which takes advantage of noise-induced thermalization and relies on incoherent quantum tunneling at finite temperature. We theoretically analyze the performance of this algorithm considering a p-spin model that allows for a mean-field quasiclassical solution and, at the same time, demonstrates the first-order phase transition and exponential degeneracy of states, typical characteristics of spin glasses. We demonstrate that finite-temperature effects introduced by the noise are particularly important for the dynamics in the presence of the exponential degeneracy of metastable states. We determine the optimal regime of the open-system quantum annealing algorithm for this model and find that it can outperform simulated annealing in a range of parameters. Large-scale multiqubit quantum tunneling is instrumental for the quantum speedup in this model, which is possible because of the unusual nonmonotonous temperature dependence of the quantum-tunneling action in this model, where the most efficient transition rate corresponds to zero temperature. This model calculation is the first analytically tractable example where open-system quantum annealing algorithm outperforms simulated annealing, which can, in principle, be realized using an analog quantum computer.

  7. Are voluntary wheel running and open-field behavior correlated in mice? Different answers from comparative and artificial selection approaches.

    Science.gov (United States)

    Careau, Vincent; Bininda-Emonds, Olaf R P; Ordonez, Genesis; Garland, Theodore

    2012-09-01

    Voluntary wheel running and open-field behavior are probably the two most widely used measures of locomotion in laboratory rodents. We tested whether these two behaviors are correlated in mice using two approaches: the phylogenetic comparative method using inbred strains of mice and an ongoing artificial selection experiment on voluntary wheel running. After taking into account the measurement error and phylogenetic relationships among inbred strains, we obtained a significant positive correlation between distance run on wheels and distance moved in the open-field for both sexes. Thigmotaxis was negatively correlated with distance run on wheels in females but not in males. By contrast, mice from four replicate lines bred for high wheel running did not differ in either distance covered or thigmotaxis in the open field as compared with mice from four non-selected control lines. Overall, results obtained in the selection experiment were generally opposite to those observed among inbred strains. Possible reasons for this discrepancy are discussed.

  8. Open access, open education resources and open data in Uganda.

    Science.gov (United States)

    Salvo, Ivana Di; Mwoka, Meggie; Kwaga, Teddy; Rukundo, Priscilla Aceng; Ernest, Dennis Ssesanga; Osaheni, Louis Aikoriogie; John, Kasibante; Shafik, Kasirye; de Sousa, Agostinho Moreira

    2015-01-01

    As a follow up to OpenCon 2014, International Federation of Medical Students' Associations (IFMSA) students organized a 3 day workshop Open Access, Open Education Resources and Open Data in Kampala from 15-18 December 2014. One of the aims of the workshop was to engage the Open Access movement in Uganda which encompasses the scientific community, librarians, academia, researchers and students. The IFMSA students held the workshop with the support of: Consortium for Uganda University Libraries (CUUL), The Right to Research Coalition, Electronic Information for Libraries (EIFL), Makerere University, International Health Sciences University (IHSU), Pan African Medical Journal (PAMJ) and the Centre for Health Human Rights and Development (CEHURD). All these organizations are based or have offices in Kampala. The event culminated in a meeting with the Science and Technology Committee of Parliament of Uganda in order to receive the support of the Ugandan Members of Parliament and to make a concrete change for Open Access in the country.

  9. Ontogeny of open field activity in rats after neonatal lesioning of the mesocortical dopaminergic projection

    NARCIS (Netherlands)

    Kalsbeek, A.; de Bruin, J. P.; Matthijssen, M. A.; Uylings, H. B.

    1989-01-01

    In order to examine the effect of neonatal depletion of the dopaminergic mesocortical projection on the development of a prefrontal cortex-mediated behaviour the ontogeny of open field behaviour was studied after neonatal depletion of cortical dopamine. Cortical dopamine was depleted by neonatal

  10. Dependence of the amount of open magnetic flux on the direction of the interplanetary magnetic field

    International Nuclear Information System (INIS)

    Akasofu, S.I.; Ahn, B.H.

    1980-01-01

    The power generated by the solar wind-magnetosphere dynamo is proportional to the amount of the open magnetic flux phi. It is difficult to use this fact in determining observationally the dependence of phi on the orientation of the interplanetary magnetic field vector. It is shown that, for a simple vacuum superposition of the earth's dipole field and a uniform magnetic field, PHI is very closely proportional to sin(theta/2) for a wide range of the intensity of the uniform field, where theta denotes the polar angle of the interplanetary magnetic field vector in the Y-Z plane of solar-magnetospheric coordinates. (author)

  11. Quasi-open inflation

    CERN Document Server

    García-Bellido, J; Montes, X; Garcia-Bellido, Juan; Garriga, Jaume; Montes, Xavier

    1998-01-01

    We show that a large class of two-field models of single-bubble open inflation do not lead to infinite open universes, as it was previously thought, but to an ensemble of very large but finite inflating `islands'. The reason is that the quantum tunneling responsible for the nucleation of the bubble does not occur simultaneously along both field directions and equal-time hypersurfaces in the open universe are not synchronized with equal-density or fixed-field hypersurfaces. The most probable tunneling trajectory corresponds to a zero value of the inflaton field; large values, necessary for the second period of inflation inside the bubble, only arise as localized fluctuations. The interior of each nucleated bubble will contain an infinite number of such inflating regions of comoving size of order $\\gamma^{-1}$, where $\\gamma$ depends on the parameters of the model. Each one of these islands will be a quasi-open universe. Since the volume of the hyperboloid is infinite, inflating islands with all possible values...

  12. Open Access Policies of Research Funders: The Case Study of the Austrian Science Fund (FWF)

    OpenAIRE

    Tonto, Yaşar; Doğan, Güleda; Al, Umut; Madran, Orçun

    2015-01-01

    The Austrian Science Fund (FWF) is the main funder for basic research in Austria. FWF has been instrumental in promoting Open Access in Austria and elsewhere and possesses a strong Open Access policy for the research it funds. This case study presents FWF as a good practice of an effective funder policy on account of its comprehensive strategy and multi-faceted approach for implementing and supporting it.

  13. Open Access to Research Data Accessing, using and publishing collections of textual data in digital literary studies

    OpenAIRE

    Schöch, Christof

    2015-01-01

    Introduction What is open access to research data? Related issues A closer look What can you do with open research data? What is required from research data? Do resources fulfil these requirements? Why is getting access good, but giving access better? Current issues Some challenges Main hindrance: Legal issues Conclusions Recommended readings

  14. Open problems in mathematics

    CERN Document Server

    Nash, Jr, John Forbes

    2016-01-01

    The goal in putting together this unique compilation was to present the current status of the solutions to some of the most essential open problems in pure and applied mathematics. Emphasis is also given to problems in interdisciplinary research for which mathematics plays a key role. This volume comprises highly selected contributions by some of the most eminent mathematicians in the international mathematical community on longstanding problems in very active domains of mathematical research. A joint preface by the two volume editors is followed by a personal farewell to John F. Nash, Jr. written by Michael Th. Rassias. An introduction by Mikhail Gromov highlights some of Nash’s legendary mathematical achievements. The treatment in this book includes open problems in the following fields: algebraic geometry, number theory, analysis, discrete mathematics, PDEs, differential geometry, topology, K-theory, game theory, fluid mechanics, dynamical systems and ergodic theory, cryptography, theoretical computer sc...

  15. Energetic electron anisotropies in the magnetotail - Identification of open and closed field lines

    Science.gov (United States)

    Baker, D. N.; Stone, E. C.

    1976-01-01

    Unidirectional anisotropies in the energetic electron fluxes (E greater than or equal to about 200 keV) have been observed in the earth's magnetotail with the Caltech Electron/Isotope Spectrometer on IMP-8. The anisotropies occur during periods of enhanced fluxes and provide essential information on the topology (open or closed) of the magnetotail field lines which are associated with recently identified acceleration regions.

  16. Research in the fields of medicine in Slovenia – research potential, funding, and publications

    Directory of Open Access Journals (Sweden)

    Stojan Pečlin

    2012-09-01

    Conclusions: The size of the human research potential in the fields of medicine in Slovenia is modest. The majority of researchers are also engaged in medical practice and education. Consequently, funds from public sources for research per researcher are low. Research fields of medicine primarly require an increase in human research resources, which can then provide a basis for a rise in funding and the impact of its research results becoming comparable to the EU and world averages.

  17. Role of library's subscription licenses in promoting open access to scientific research

    KAUST Repository

    Buck, Stephen

    2018-01-01

    This presentation, based on KAUST’’s experience to date, will attempt to explain the different ways of bringing Open Access models to scientific Publisher’s licenses. Our dual approach with offset pricing is to redirect subscription money to publishing money and embed green open access deposition terms in understandable language in our license agreements. Resolving the inherent complexities in open access publishing, repository depositions and offsetting models will save libraries money and also time wasted on tedious and unnecessary administration work. Researchers will also save their time with overall clarity and transparency. This will enable trust and, where mistakes are made, and there inevitably will be with untried models, we can learn from these mistakes and make better, more robust services with auto deposition of our articles to our repository fed by Publishers’ themselves. The plan is to cover all Publishers with OA license terms for KAUST author’s right while continuing our subscription to them. There are marketing campaigns, awareness sessions are planned, in addition to establishing Libguides to help researchers, in addition to manage offset pricing models.

  18. Role of library's subscription licenses in promoting open access to scientific research

    KAUST Repository

    Buck, Stephen

    2018-04-30

    This presentation, based on KAUST’’s experience to date, will attempt to explain the different ways of bringing Open Access models to scientific Publisher’s licenses. Our dual approach with offset pricing is to redirect subscription money to publishing money and embed green open access deposition terms in understandable language in our license agreements. Resolving the inherent complexities in open access publishing, repository depositions and offsetting models will save libraries money and also time wasted on tedious and unnecessary administration work. Researchers will also save their time with overall clarity and transparency. This will enable trust and, where mistakes are made, and there inevitably will be with untried models, we can learn from these mistakes and make better, more robust services with auto deposition of our articles to our repository fed by Publishers’ themselves. The plan is to cover all Publishers with OA license terms for KAUST author’s right while continuing our subscription to them. There are marketing campaigns, awareness sessions are planned, in addition to establishing Libguides to help researchers, in addition to manage offset pricing models.

  19. Variable stars in the field of open cluster NGC 2126

    International Nuclear Information System (INIS)

    Liu Shunfang; Wu Zhenyu; Zhang Xiaobin; Wu Jianghua; Ma Jun; Jiang Zhaoji; Chen Jiansheng; Zhou Xu

    2009-01-01

    We report the results of a time-series CCD photometric survey of variable stars in the field of open cluster NGC 2126. In about a one square degree field covering the cluster, a total of 21 variable candidates are detected during this survey, of which 16 are newly found. The periods, classifications and spectral types of 14 newly discovered variables are discussed, which consist of six eclipsing binary systems, three pulsating variable stars, three long period variables, one RS CVn star, and one W UMa or δ Scuti star. In addition, there are two variable candidates, the properties of which cannot be determined. By a method based on fitting observed spectral energy distributions of stars with theoretical ones, the membership probabilities and the fundamental parameters of this cluster are determined. As a result, five variables are probably members of NGC 2126. The fundamental parameters of this cluster are determined as: metallicity to be 0.008 Z o-dot , age log(t) = 8.95, distance modulus (m - M) 0 = 10.34 and reddening value E (B - V) = 0.55 mag.

  20. WASP (Write a Scientific Paper): Open access unsolicited emails for scholarly work - Young and senior researchers perspectives.

    Science.gov (United States)

    Cuschieri, Sarah; Grech, Victor

    2018-04-20

    The increasing demand on academics and researchers to publish has led to the development of fake journals (also known as predatory journals). Such journals lack peer review and precipitate unfair criticism toward legitimate open access journals. Predatory journals tend to bombard a researcher's mailbox on a daily basis, inviting authors to submit a review/manuscript/opinion/short case to their journal while promising expedited publication - against a fee. This study assessed the unsolicited emails received over the period of November 2017 by a young and by a senior researcher. The young researcher received a substantially higher amount of emails (n = 101) compared to the senior researcher (n = 23). The article processing costs for solicited journals received, ranged between $49 and $3019. These journals are almost all only indexed in Google Scholar and do not display any meaningful journal metrics. Furthermore, the majority of the unsolicited emails were not relevant to the researcher's field of study. Therefore authors and readers alike should evaluate emails received with regard to journal legitimacy prior to submission of work to possibly predatory journals. Copyright © 2018 Elsevier B.V. All rights reserved.

  1. Employing open/hidden administration in psychotherapy research: A randomized-controlled trial of expressive writing

    Science.gov (United States)

    Tondorf, Theresa; Kaufmann, Lisa-Katrin; Degel, Alexander; Locher, Cosima; Birkhäuer, Johanna; Gerger, Heike; Ehlert, Ulrike

    2017-01-01

    Psychotherapy has been shown to be effective, but efforts to prove specific effects by placebo-controlled trials have been practically and conceptually hampered. We propose that adopting open/hidden designs from placebo research would offer a possible way to establish specificity in psychotherapy. Therefore, we tested the effects of providing opposing treatment rationales in an online expressive writing intervention on affect in healthy subjects. Results indicate that it was possible to conduct the expressive writing intervention both covertly and openly, but that participants in the hidden administration condition did not fully benefit from the otherwise effective expressive writing intervention in the long-run. Effect sizes between open and hidden administration groups were comparable to pre-post effect sizes of the intervention. While this finding is important for the understanding of psychotherapy's effects per se, it also proves that alternative research approaches to establish specificity are feasible and informative in psychotherapy research. Trial registration: German Clinical Trials Register DRKS00009428 PMID:29176768

  2. An Alternative Interpretation of the Relationship between the Inferred Open Solar Flux and the Interplanetary Magnetic Field

    Science.gov (United States)

    Riley, Pete

    2007-01-01

    Photospheric observations at the Wilcox Solar Observatory (WSO) represent an uninterrupted data set of 32 years and are therefore unique for modeling variations in the magnetic structure of the corona and inner heliosphere over three solar cycles. For many years, modelers have applied a latitudinal correction factor to these data, believing that it provided a better estimate of the line-of-sight magnetic field. Its application was defended by arguing that the computed open flux matched observations of the interplanetary magnetic field (IMF) significantly better than the original WSO correction factor. However, no physically based argument could be made for its use. In this Letter we explore the implications of using the constant correction factor on the value and variation of the computed open solar flux and its relationship to the measured IMF. We find that it does not match the measured IMF at 1 AU except at and surrounding solar minimum. However, we argue that interplanetary coronal mass ejections (ICMEs) may provide sufficient additional magnetic flux to the extent that a remarkably good match is found between the sum of the computed open flux and inferred ICME flux and the measured flux at 1 AU. If further substantiated, the implications of this interpretation may be significant, including a better understanding of the structure and strength of the coronal field and I N providing constraints for theories of field line transport in the corona, the modulation of galactic cosmic rays, and even possibly terrestrial climate effects.

  3. 75 FR 18484 - Emerging Technology and Research Advisory Committee; Notice of Open Meeting

    Science.gov (United States)

    2010-04-12

    ... Emerging Technologies Analysis. 2. ETRAC Panel on Emerging Technologies. 3. History of the Laser. 4... DEPARTMENT OF COMMERCE Bureau of Industry and Security Emerging Technology and Research Advisory Committee; Notice of Open Meeting The Emerging Technology and Research Advisory Committee (ETRAC) [[Page...

  4. Revista ORL at Open Science Ecosystem

    Directory of Open Access Journals (Sweden)

    Tránsito FERRERAS FERNÁNDEZ

    2018-05-01

    Full Text Available In October 2017 they were held at the University of Salamanca the congress Open Knowledge Ecosystems (ACE 2017 posed as an international meeting point for specialists in open access. The congress allowed to approach the open knowledge from the perspectives I + D + i, offering papers and communications on research related to Open Access, as well as experiences developed in repositories and institutions and approaches to innovative trends in any of the fields of open knowledge.The experience of Revista ORL was present in ECA 2017 through a joint communication of several authors titled Nuevas vías de publicación para revistas biomédicas. Proyecto Revista ORL de Ediciones Universidad de Salamanca, offering an overview of the history of the Revista as an open edition project. Although on that occasion it was called a project, now we should call it "reality" fully consolidated because the data on results obtained.Open Science represents a paradigm change in the way to make science. Although this doesn't change substantially with respect to its motivations and objectives, it changes its methods. The change lies in how it is done, not in what is done. It is an open science, collaborative and made with and for society.The concept of Open Science has been preceded by Open Access to academic content and this may have conditioned its understanding. Open Access has been assimilated only with open access to articles, while with Open Science it is considered that what must be open is any research result (articles + data as well as the auxiliary instruments used (for example, laboratory notebooks. However, the double meaning of "open" (free and free is the same for the two concepts.In this paper we pose questions such as What is Open Science? What are the motivations of governments for its promotion? What components does make up this ecosystem? What are the implications for agents of scientific research? What does represent all this for the edition of

  5. Open Science Strategies in Research Policies: A Comparative Exploration of Canada, the US and the UK

    Science.gov (United States)

    Lasthiotakis, Helen; Kretz, Andrew; Sá, Creso

    2015-01-01

    Several movements have emerged related to the general idea of promoting "openness" in science. Research councils are key institutions in bringing about changes proposed by these movements, as sponsors and facilitators of research. In this paper we identify the approaches used in Canada, the US and the UK to advance open science, as a…

  6. Myocardial infarction increases progressive visual field defects in well treated early primary open angle glaucoma--a prospective case control study.

    Science.gov (United States)

    Mondal, Lakshmikanta; Baidya, Krishnapada; Choudhury, Himadri; Roy, Rupam

    2013-06-01

    The purpose of the study was to evaluate the progression of glaucomatous field damage in patients with stable primary open angle glaucoma after an attack of myocardial infarction. In this case control study, 62 open angle glaucoma patients were selected and regularly followed up. Among 62 patients, 9 had an attack of myocardial infarction. The intra-ocular pressure and visual field progression of both the groups (myocardial infarction versus no myocardial infarction) were analysed. Three (33.3%) out of 9 patients who had suffered from myocardial infarction showed progressive visual field loss whereas only 9 (16.9%) out of 53 patients who did not suffer from myocardial infarction, showed progressive field changes. Both the groups had stable target intra-ocular pressure between 14 and 16 mm Hg. Myocardial infarction may adversely influence the progression of primary open angle glaucoma which is suspected to result from ischaemia induced neuronal loss and only control of intraocular pressure is not the only solution. We have to look for other drugs that prevents ischaemia induced neuronal damage.

  7. Effects of methamphetamine exposure on anxiety-like behavior in the open field test, corticosterone, and hippocampal tyrosine hydroxylase in adolescent and adult mice.

    Science.gov (United States)

    Struntz, Katelyn H; Siegel, Jessica A

    2018-08-01

    Methamphetamine (MA) is a psychomotor stimulant drug that can alter behavior, the stress response system, and the dopaminergic system. The effects of MA can be modulated by age, however relatively little research has examined the acute effects of MA in adolescents and how the effects compare to those found in adults. The hippocampal dopamine system is altered by MA exposure and can modulate anxiety-like behavior, but the effects of MA on the hippocampal dopamine system have not been well studied, especially in adolescent animals. In order to assess potential age differences in the effects of MA exposure, this research examined the effects of acute MA exposure on locomotor and anxiety-like behavior in the open field test, plasma corticosterone levels, and hippocampal total tyrosine hydroxylase and phosphorylated tyrosine hydroxylase levels in adolescent and adult male C57BL/6 J mice. Tyrosine hydroxylase is the rate limiting enzyme in the synthesis of dopamine and was used as a marker of the hippocampal dopaminergic system. Mice were exposed to saline or 4 mg/kg MA and locomotor and anxiety-like behavior were measured in the open field test. Serum and brains were collected immediately after testing and plasma corticosterone and hippocampal total tyrosine hydroxylase and phosphorylated tyrosine hydroxylase levels measured. MA-exposed mice showed increased locomotor activity and anxiety-like behavior in the open field test compared with saline controls, regardless of age. There was no effect of MA on plasma corticosterone levels or hippocampal total tyrosine hydroxylase or phosphorylated tyrosine hydroxylase levels in either adolescent or adult mice. These data suggest that acute MA exposure during adolescence and adulthood increases locomotor activity and anxiety-like behavior but does not alter plasma corticosterone levels or hippocampal total tyrosine hydroxylase or phosphorylated tyrosine hydroxylase levels, and that these effects are not modulated by age

  8. Open magnetic structures on the sun

    International Nuclear Information System (INIS)

    Levine, R.H.; Altschuler, M.D.; Harvey, J.W.; Jackson, B.V.

    1977-01-01

    High-resolution harmonic analysis of the solar magnetic field has been used successfully to calculate the geometry of open magnetic field lines in the solar corona. Comparison of the loci of open field line footpoints with solar X-ray photographs shows that all of the coronal holes during two solar rotations are successfully represented, including details of their evolution. Some open magnetic configurations derived in the calculations precede by up to one solar rotation the manifestation of coincident dark areas on the X-ray photographs. The only other areas that contribute open field lines to the corona are separations between active-region loop systems. By varying the radius at which field lines are forced to be open in the calculation, it is possible to more closely reproduce the surface configuration of particular coronal holes. Comparison of the size of X-ray holes with the fraction of the solar surface covered by open field lines leads to the conclusion that a significant part of the area of coronal holes must contain closed magnetic fields. Comparison of open field lines which lie in the equatorial plane of the Sun with solar wind data indicates that eventual high-speed solar wind streams are associated with those parts of open magnetic structures that diverge the least. Several important questions raised by this study are under investigation using data for the entire Skylab period

  9. Open- and closed-formula laboratory animal diets and their importance to research.

    Science.gov (United States)

    Barnard, Dennis E; Lewis, Sherry M; Teter, Beverly B; Thigpen, Julius E

    2009-11-01

    Almost 40 y ago the scientific community was taking actions to control environmental factors that contribute to variation in the responses of laboratory animals to scientific manipulation. Laboratory animal diet was recognized as an important variable. During the 1970s, the American Institute of Nutrition, National Academy of Science, Institute of Laboratory Animal Resources, and Laboratory Animals Centre Diets Advisory Committee supported the use of 'standard reference diets' in biomedical research as a means to improve the ability to replicate research. As a result the AIN76 purified diet was formulated. During this same time, the laboratory animal nutritionist at the NIH was formulating open-formula, natural-ingredient diets to meet the need for standardized laboratory animal diets. Since the development of open-formula diets, fixed-formula and constant-nutrient-concentration closed-formula laboratory animal natural ingredient diets have been introduced to help reduce the potential variation diet can cause in research.

  10. Open quantum systems and the two-level atom interacting with a single mode of the electromagnetic field

    International Nuclear Information System (INIS)

    Sandulescu, A.; Stefanescu, E.

    1987-07-01

    On the basis of Lindblad theory of open quantum systems we obtain new optical equations for the system of two-level atom interacting with a single mode of the electromagnetic field. The conventional Block equations in a generalized form with field phases are obtained in the hypothesis that all the terms are slowly varying in the rotating frame.(authors)

  11. Low mass planets in protoplanetary disks with net vertical magnetic fields: the Planetary Wake and Gap Opening

    OpenAIRE

    Zhu, Zhaohuan; Stone, James M.; Rafikov, Roman R.

    2013-01-01

    We study wakes and gap opening by low mass planets in gaseous protoplanetary disks threaded by net vertical magnetic fields which drive magnetohydrodynamical (MHD) turbulence through the magnetorotational instabilty (MRI), using three dimensional simulations in the unstratified local shearing box approximation. The wakes, which are excited by the planets, are damped by shocks similar to the wake damping in inviscid hydrodynamic (HD) disks. Angular momentum deposition by shock damping opens ga...

  12. Dose-response effects of systemic anandamide administration in mice sequentially submitted to the open field and elevated plus-maze tests.

    Science.gov (United States)

    Ribeiro, A; Ferraz-de-Paula, V; Pinheiro, M L; Palermo-Neto, J

    2009-06-01

    The endocannabinoid system is involved in the control of many physiological functions, including the control of emotional states. In rodents, previous exposure to an open field increases the anxiety-like behavior in the elevated plus-maze. Anxiolytic-like effects of pharmacological compounds that increase endocannabinoid levels have been well documented. However, these effects are more evident in animals with high anxiety levels. Several studies have described characteristic inverted U-shaped dose-response effects of drugs that modulate the endocannabinoid levels. However, there are no studies showing the effects of different doses of exogenous anandamide, an endocannabinoid, in animal models of anxiety. Thus, in the present study, we determined the dose-response effects of exogenous anandamide at doses of 0.01, 0.1, and 1.0 mg/kg in C57BL/6 mice (N = 10/group) sequentially submitted to the open field and elevated plus-maze. Anandamide was diluted in 0.9% saline, ethyl alcohol, Emulphor (18:1:1) and administered ip (0.1 mL/10 g body weight); control animals received the same volume of anandamide vehicle. Anandamide at the dose of 0.1 mg/kg (but not of 0.01 or 1 mg/kg) increased (P open field, as well as the exploration of the open arms of the elevated plus-maze. Thus, exogenous anandamide, like pharmacological compounds that increase endocannabinoid levels, promoted a characteristic inverted U-shaped dose-response effect in animal models of anxiety. Furthermore, anandamide (0.1 mg/kg) induced an anxiolytic-like effect in the elevated plus-maze (P open field test.

  13. Role of herbicide treatments and application times in cogongrass eradication under open field infestation scenario

    Science.gov (United States)

    A Cogongrass eradication project was conducted from spring 2008 through fall 2011 on natural, open-field Cogongrass infestations at two locations near Tilman's Corner and Bayou La Batre in southwestern Alabama. Treatments consisted of glyphosate alone (4 lb/acre), imazapyr alone (0.75 lb/acre) and ...

  14. FieldTrip: Open source software for advanced analysis of MEG, EEG, and invasive electrophysiological data

    NARCIS (Netherlands)

    Oostenveld, R.; Fries, P.; Maris, E.G.G.; Schoffelen, J.M.

    2011-01-01

    This paper describes FieldTrip, an open source software package that we developed for the analysis of MEG, EEG, and other electrophysiological data. The software is implemented as a MATLAB toolbox and includes a complete set of consistent and user-friendly high-level functions that allow

  15. Applying Open Researchers and Contributors ID in scholarly journals

    Directory of Open Access Journals (Sweden)

    Jeonghee Im

    2015-02-01

    Full Text Available Open Researchers and Contributors ID (ORCID launched its registry services in October 2012. Consequently, adding personal information to the ORCID registry became routine work for researchers. To add ORCID to an online article, the tag needs to be included in the Journal Article Tag Suite extensible markup language file, if such a file has been produced by the publisher. Subsequently, all co-authors’ ORCID can be easily and conveniently collected and then integrated into the manuscript management system. In the current age of information and the Internet, journals need to keep pace with the surge of new standards and technologies. Editors should be able to accept and apply these new systems rapidly.

  16. Raven-II: an open platform for surgical robotics research.

    Science.gov (United States)

    Hannaford, Blake; Rosen, Jacob; Friedman, Diana W; King, Hawkeye; Roan, Phillip; Cheng, Lei; Glozman, Daniel; Ma, Ji; Kosari, Sina Nia; White, Lee

    2013-04-01

    The Raven-II is a platform for collaborative research on advances in surgical robotics. Seven universities have begun research using this platform. The Raven-II system has two 3-DOF spherical positioning mechanisms capable of attaching interchangeable four DOF instruments. The Raven-II software is based on open standards such as Linux and ROS to maximally facilitate software development. The mechanism is robust enough for repeated experiments and animal surgery experiments, but is not engineered to sufficient safety standards for human use. Mechanisms in place for interaction among the user community and dissemination of results include an electronic forum, an online software SVN repository, and meetings and workshops at major robotics conferences.

  17. The Use of an Open Field Model to Assess Sound-Induced Fear and Anxiety Associated Behaviors in Labrador Retrievers.

    Science.gov (United States)

    Gruen, Margaret E; Case, Beth C; Foster, Melanie L; Lazarowski, Lucia; Fish, Richard E; Landsberg, Gary; DePuy, Venita; Dorman, David C; Sherman, Barbara L

    2015-01-01

    Previous studies have shown that the playing of thunderstorm recordings during an open-field task elicits fearful or anxious responses in adult beagles. The goal of our study was to apply this open field test to assess sound-induced behaviors in Labrador retrievers drawn from a pool of candidate improvised explosive devices (IED)-detection dogs. Being robust to fear-inducing sounds and recovering quickly is a critical requirement of these military working dogs. This study presented male and female dogs, with 3 minutes of either ambient noise (Days 1, 3 and 5), recorded thunderstorm (Day 2), or gunfire (Day 4) sounds in an open field arena. Behavioral and physiological responses were assessed and compared to control (ambient noise) periods. An observer blinded to sound treatment analyzed video records of the 9-minute daily test sessions. Additional assessments included measurement of distance traveled (activity), heart rate, body temperature, and salivary cortisol concentrations. Overall, there was a decline in distance traveled and heart rate within each day and over the five-day test period, suggesting that dogs habituated to the open field arena. Behavioral postures and expressions were assessed using a standardized rubric to score behaviors linked to canine fear and anxiety. These fear/anxiety scores were used to evaluate changes in behaviors following exposure to a sound stressor. Compared to control periods, there was an overall increase in fear/anxiety scores during thunderstorm and gunfire sound stimuli treatment periods. Fear/anxiety scores were correlated with distance traveled, and heart rate. Fear/anxiety scores in response to thunderstorm and gunfire were correlated. Dogs showed higher fear/anxiety scores during periods after the sound stimuli compared to control periods. In general, candidate IED-detection Labrador retrievers responded to sound stimuli and recovered quickly, although dogs stratified in their response to sound stimuli. Some dogs were

  18. A model to generate beam profiles of the Varian Clinac 4 for three-dimensional dose calculation: open fields

    International Nuclear Information System (INIS)

    Lam, K.S.; Lam, W.C.

    1984-01-01

    For the Clinac 4, open field profiles measured in the principal plane have higher intensity ''horns'' than those in off-axis planes. The maximum deviation occurs at 1-cm depth, where in the worst case of large field sizes and off-axis distances the deviation can be as high as 16% in the region near the horns. A model is proposed to generate open field beam profiles in off-axis planes, based on measured profiles in the transverse principal plane and in the largest field size diagonal plane of the machine. Within the central 90% portion of the field, the maximum deviation of the generated profiles from the measured ones at the same off-axis distance varies from about 3% at 1-cm depth to about 2% at 13-cm depth and then increases to less than 5% at 25-cm depth, even for very large field sizes and off-axis distances. Very little additional computer time and data storage are required for this procedure. Using these profiles, the Milan and Bentley method can be extended to three-dimensional treatment planning with good accuracy

  19. Confinement of plasma along shaped open magnetic fields from the centrifugal force of supersonic plasma rotation.

    Science.gov (United States)

    Teodorescu, C; Young, W C; Swan, G W S; Ellis, R F; Hassam, A B; Romero-Talamas, C A

    2010-08-20

    Interferometric density measurements in plasmas rotating in shaped, open magnetic fields demonstrate strong confinement of plasma parallel to the magnetic field, with density drops of more than a factor of 10. Taken together with spectroscopic measurements of supersonic E × B rotation of sonic Mach 2, these measurements are in agreement with ideal MHD theory which predicts large parallel pressure drops balanced by centrifugal forces in supersonically rotating plasmas.

  20. Across the Arctic Teachers Experience Field Research

    Science.gov (United States)

    Warnick, W. K.; Warburton, J.; Wiggins, H. V.; Marshall, S. A.; Darby, D. A.

    2005-12-01

    From studying snow geese on the North Slope of Alaska to sediment coring aboard the U.S. Coast Guard Cutter Healy in the Arctic Ocean, K-12 teachers embark on scientific expeditions as part of a program that strives to make science in the Arctic a "virtual" reality. In the past two years, seventeen K-12 teachers have participated in Teachers and Researchers Exploring and Collaborating (TREC), a program that pairs teachers with researchers to improve science education through arctic field experiences. TREC builds on the scientific and cultural opportunities of the Arctic, linking research and education through topics that naturally engage students and the wider public. TREC includes expeditions as diverse as studying plants at Toolik Field Station, a research facility located 150 miles above the Arctic Circle; climate change studies in Norway's Svalbard archipelago; studying rivers in Siberia; or a trans-arctic expedition aboard the USCGC Healy collecting an integrated geophysical data set. Funded by the National Science Foundation Office of Polar Programs, TREC offers educators experiences in scientific inquiry while encouraging the public and students to become active participants in the scientific inquiry by engaging them virtually in arctic research. TREC uses online outreach elements to convey the research experience to a broad audience. While in remote field locations, teachers and researchers interact with students and the public through online seminars and live calls from the field, online journals with accompanying photos, and online bulletin boards. Since the program's inception in 2004, numerous visitors have posted questions or interacted with teachers, researchers, and students through the TREC website (http://www.arcus.org/trec). TREC teachers are required to transfer their experience of research and current science into their classroom through the development of relevant activities and resources. Teachers and researchers are encouraged to participate

  1. [Association between the canine monoamine oxidase B (MAOB) gene polymorphisms and behavior of puppies in open-field test].

    Science.gov (United States)

    Li, Xiao-Hui; Xu, Han-Kun; Mao, Da-Gan; Ma, Da-Jun; Chen, Peng; Yang, Li-Guo

    2006-11-01

    Excitability, activity and exploration behavior of puppies in a novel open-field were tested in a total of 204 two-month-old German shepherd dog, labrador retriever or English springer spaniel puppies. The polymorphisms of monoamine oxidase B gene (MAOB) were detected by PCR-RFLP. Statistics analysis indicated that genotype and allele frequencies of the polymorphisms were significantly different among three breeds (P open-field test. The results showed that MAOB gene polymorphisms had a significant effect on walking time, squares crossed, lying time, the times of standing up against walls(P times of posture change (P=0.064). Walking time and squares crossed were higher in TT genotype puppies than those in TC and CC puppies (P times of posture change and standing up against walls were also higher than those in CC (P time in CC genotype puppies were higher than that in TT (P walking time, lying time, squares crossed, the times of posture change, the times of standing up against walls in the three dog breeds that was highly statistically significant (P open-field test and TT genotype has favorable effects in these behavior traits.

  2. Research, Collaboration, and Open Science Using Web 2.0

    Directory of Open Access Journals (Sweden)

    Kevin Shee

    2010-10-01

    Full Text Available There is little doubt that the Internet has transformed the world in which we live. Information that was once archived in bricks and mortar libraries is now only a click away, and people across the globe have become connected in a manner inconceivable only 20 years ago. Although many scientists and educators have embraced the Internet as an invaluable tool for research, education and data sharing, some have been somewhat slower to take full advantage of emerging Web 2.0 technologies. Here we discuss the benefits and challenges of integrating Web 2.0 applications into undergraduate research and education programs, based on our experience utilizing these technologies in a summer undergraduate research program in synthetic biology at Harvard University. We discuss the use of applications including wiki-based documentation, digital brainstorming, and open data sharing via the Web, to facilitate the educational aspects and collaborative progress of undergraduate research projects. We hope to inspire others to integrate these technologies into their own coursework or research projects.

  3. Issues in E-Research: Log In/Out Virtual Fields

    Directory of Open Access Journals (Sweden)

    Shesha Kanta PANGENI

    2017-07-01

    Full Text Available Evolution of technology and its tremendous use in education has changed the ways of educational services in higher education around the world. There is worldwide access to higher education through virtual learning environments. This is a new avenue for 21st century education and within a short time, it has been able to establish new culture of learning i.e. e-learning or online learning. As a result, e-learning has been the greater field for educational research. In this context, this paper focuses on methodological issues of the Internet mediated research (e-Research with particular focus on virtual fields. Paper explores and discusses on possible sources of data, methods of data collection, process of analysis and ethical issues to adopt research with virtual fields. In doing so, the purpose is to reveal answer to the question: how do e-Researchers deal with methodological issues related to collecting data, determining data sources, data analysis/interpretation, and ethical considerations? Paper presents examples from the Internet mediated empirical studies. Conclusion of the paper is that e-field or cyberspace is an avenue for modern researchers. Researchers are supported with various Information Communication Technology (ICT tools for field access, data collection, analysis and interpretation. However, they need to pay full attention to deal with major issues such as locating and gaining access to virtual/Internet-mediated fields, selecting e-participants and working with them, and using varieties of ICT tools for data collection, analysis and interpretation.

  4. Effects of environmental enrichment and paradoxical sleep deprivation on open-field behavior of amphetamine-treated mice.

    Science.gov (United States)

    Fukushiro, Daniela Fukue; Calzavara, Mariana Bendlin; Trombin, Thaís Fernanda; Lopez, Giorgia Batlle; Abílio, Vanessa Costhek; Andersen, Monica Levy; Tufik, Sergio; Frussa-Filho, Roberto

    2007-11-23

    Environmental enrichment or paradoxical sleep deprivation (PSD) has been shown to modify some responses elicited by drugs of abuse. The aims of the present study were to examine the effects of environmental enrichment and PSD, conducted separately or in association, on open-field behavior elicited by amphetamine (AMP) in mice. Male C57BL/6 mice were randomly assigned to live in either an enriched environmental condition (EC) or a standard environmental condition (SC) for 12 months since weaning. Some of the EC and SC mice were sleep deprived for 48 h, while others were maintained in their home-cages. Immediately after PSD or home-cage stay, the animals received an ip injection of saline, 2.5 mg/kg AMP or 5.0 mg/kg AMP. Fifteen minutes later, their open-field behavior was quantified. Whereas PSD enhanced total and peripheral locomotor activity of acutely AMP-treated mice, environmental enrichment presented only a trend toward enhancement. When PSD and environmental enrichment were combined, an increase in the total and peripheral locomotion frequencies of AMP-treated animals, similar to that observed after PSD, was revealed. In addition, PSD, environmental enrichment or their combination did not modify the effects of AMP on the other open-field behavioral parameters that were analyzed. The present findings demonstrate that some (but not all) of the behavioral effects caused by AMP acute administration can be similarly and specifically enhanced by both environmental enrichment and PSD in C57BL/6 mice.

  5. Evaluation Of Open, Wedge Filtered And Half Block Profile For Single And Plan Parallel Field For 60Co Teletherapy Unit

    International Nuclear Information System (INIS)

    Heru-Prasetio; Nasukha; Soejoko, Djarwani S

    2003-01-01

    TPS shall be evaluated with experimental data before it is used for patient treatment. This experiment was performed using small water phantom, at the depth of 10 cm, SSD technique for single beam and 16 cm, SAD technique for plan parallel beam. Measuring device used in this experiment is Farmer 2571 detector. It was found differences between experiment and TPS iSis are not significant. Single field experiment and TPS differences of 0.6%, 3.6% and 0.1% for open, wedge filter and half-blocked field, for plan parallel experiment and TPS differences are 2.1%, 2% and 2.4% for open, wedge filter and half-blocked field. (author)

  6. SME 2.0: Roadmap towards Web 2.0-Based Open Innovation in SME-Networks - A Case Study Based Research Framework

    Science.gov (United States)

    Lindermann, Nadine; Valcárcel, Sylvia; Schaarschmidt, Mario; von Kortzfleisch, Harald

    Small- and medium sized enterprises (SMEs) are of high social and economic importance since they represent 99% of European enterprises. With regard to their restricted resources, SMEs are facing a limited capacity for innovation to compete with new challenges in a complex and dynamic competitive environment. Given this context, SMEs need to increasingly cooperate to generate innovations on an extended resource base. Our research project focuses on the aspect of open innovation in SME-networks enabled by Web 2.0 applications and referring to innovative solutions of non-competitive daily life problems. Examples are industrial safety, work-life balance issues or pollution control. The project raises the question whether the use of Web 2.0 applications can foster the exchange of creativity and innovative ideas within a network of SMEs and hence catalyze new forms of innovation processes among its participants. Using Web 2.0 applications within SMEs implies consequently breaking down innovation processes to employees’ level and thus systematically opening up a heterogeneous and broader knowledge base to idea generation. In this paper we address first steps on a roadmap towards Web 2.0-based open innovation processes within SME-networks. It presents a general framework for interaction activities leading to open innovation and recommends a regional marketplace as a viable, trust-building driver for further collaborative activities. These findings are based on field research within a specific SME-network in Rhineland-Palatinate Germany, the “WirtschaftsForum Neuwied e.V.”, which consists of roughly 100 heterogeneous SMEs employing about 8,000 workers.

  7. Naloxone effects on behavior of inbred mice with different response to emotional stress in open field test.

    Science.gov (United States)

    Nadorova, A V; Kozlovskaja, M M; Seredenin, S B

    2009-10-01

    Effects of nonspecific opiate receptor antagonist naloxone in doses of 0.1, 0.5, 1.0, 5.0, 10.0 mg/kg on open field behavior and spontaneous motor activity were studied in male BALB/c and C57Bl/6 mice. Differently directed effects of naloxone on behavioral parameters of emotional-stress reaction in BALB/c and C57Bl/6 mice were observed. Naloxone increased motor activity in the open field test in BALB/c mice, but decreased it in C57Bl/6 mice. In the absence of stress, naloxone in the studied dose range did not affect spontaneous motor activity in C57Bl/6 mice, and significantly reduced activity in BALB/c mice in doses 0.5 and 1.0 mg/kg.

  8. Characteristics of Ambient Black Carbon Mass and Size-Resolved Particle Number Concentrations during Corn Straw Open-Field Burning Episode Observations at a Rural Site in Southern Taiwan.

    Science.gov (United States)

    Cheng, Yu-Hsiang; Yang, Li-Sing

    2016-07-08

    Information on the effect of open-field burning of agricultural residues on ambient black carbon (BC) mass and size-resolved particle number concentrations is scarce. In this study, to understand the effect of such open-field burning on short-term air quality, real-time variations of the BC mass and size-resolved particle number concentrations were monitored before and during a corn straw open-field burning episode at a rural site. Correlations between the BC mass and size-resolved particle number concentrations during the episode were investigated. Moreover, the particle number size distribution and absorption Ångström exponent were determined for obtaining the characteristics of aerosol emissions from the corn straw open-field burning. The results can be used to address public health concerns and as a reference for managing similar episodes of open-field burning of agricultural residues.

  9. Using Latent Semantic Analysis to Identify Research Trends in OpenStreetMap

    Directory of Open Access Journals (Sweden)

    Sukhjit Singh Sehra

    2017-07-01

    Full Text Available OpenStreetMap (OSM, based on collaborative mapping, has become a subject of great interest to the academic community, resulting in a considerable body of literature produced by many researchers. In this paper, we use Latent Semantic Analysis (LSA to help identify the emerging research trends in OSM. An extensive corpus of 485 academic abstracts of papers published during the period 2007–2016 was used. Five core research areas and fifty research trends were identified in this study. In addition, potential future research directions have been provided to aid geospatial information scientists, technologists and researchers in undertaking future OSM research.

  10. Strategic investments in non-communicable diseases (NCD) research in Africa: the GSK Africa NCD Open Lab.

    Science.gov (United States)

    Hall, Matthew D; Dufton, Ann M; Katso, Roy M; Gatsi, Sally A; Williams, Pauline M; Strange, Michael E

    2015-01-01

    In March 2014, GSK announced a number of new strategic investments in Africa. One of these included investment of up to 25 million Pounds Sterling (£25 million) to create the world's first R&D Open Lab to increase understanding of non-communicable diseases (NCDs) in Africa. The vision is to create a new global R&D effort with GSK working in partnership with major funders, academic centres and governments to share expertise and resources to conduct high-quality research. The Africa NCD Open Lab will see GSK scientists collaborate with scientific research centres across Africa. An independent advisory board of leading scientists and clinicians will provide input to develop the strategy and selection of NCD research projects within a dynamic and networked open-innovation environment. It is hoped that these research projects will inform prevention and treatment strategies in the future and will enable researchers across academia and industry to discover and develop new medicines to address the specific needs of African patients.

  11. Assessment of anxiety in open field and elevated plus maze using infrared thermography.

    Science.gov (United States)

    Lecorps, Benjamin; Rödel, Heiko G; Féron, Christophe

    2016-04-01

    Due to their direct inaccessibility, affective states are classically assessed by gathering concomitant physiological and behavioral measures. Although such a dual approach to assess emotional states is frequently used in different species including humans, the invasiveness of procedures for physiological recordings particularly in smaller-sized animals strongly restricts their application. We used infrared thermography, a non-invasive method, to assess physiological arousal during open field and elevated plus maze tests in mice. By measuring changes in surface temperature indicative of the animals' emotional response, we aimed to improve the inherently limited and still controversial information provided by behavioral parameters commonly used in these tests. Our results showed significant and consistent thermal responses during both tests, in accordance with classical physiological responses occurring in stressful situations. Besides, we found correlations between these thermal responses and the occurrence of anxiety-related behaviors. Furthermore, initial temperatures measured at the start of each procedure (open field, elevated plus maze), which can be interpreted as a measure of the animals' initial physiological arousal, predicted the levels of activity and of anxiety-related behaviors displayed during the tests. Our results stress the strong link between physiological correlates of emotions and behaviors expressed during unconditioned fear tests. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. Opening up animal research and science–society relations? A thematic analysis of transparency discourses in the United Kingdom

    Science.gov (United States)

    McLeod, Carmen; Hobson-West, Pru

    2015-01-01

    The use of animals in scientific research represents an interesting case to consider in the context of the contemporary preoccupation with transparency and openness in science and governance. In the United Kingdom, organisations critical of animal research have long called for more openness. More recently, organisations involved in animal research also seem to be embracing transparency discourses. This article provides a detailed analysis of publically available documents from animal protection groups, the animal research community and government/research funders. Our aim is to explore the similarities and differences in the way transparency is constructed and to identify what more openness is expected to achieve. In contrast to the existing literature, we conclude that the slipperiness of transparency discourses may ultimately have transformative implications for the relationship between science and society and that contemporary openness initiatives might be sowing the seeds for change to the status quo. PMID:26009149

  13. Opening up animal research and science-society relations? A thematic analysis of transparency discourses in the United Kingdom.

    Science.gov (United States)

    McLeod, Carmen; Hobson-West, Pru

    2016-10-01

    The use of animals in scientific research represents an interesting case to consider in the context of the contemporary preoccupation with transparency and openness in science and governance. In the United Kingdom, organisations critical of animal research have long called for more openness. More recently, organisations involved in animal research also seem to be embracing transparency discourses. This article provides a detailed analysis of publically available documents from animal protection groups, the animal research community and government/research funders. Our aim is to explore the similarities and differences in the way transparency is constructed and to identify what more openness is expected to achieve. In contrast to the existing literature, we conclude that the slipperiness of transparency discourses may ultimately have transformative implications for the relationship between science and society and that contemporary openness initiatives might be sowing the seeds for change to the status quo. © The Author(s) 2015.

  14. Between and within laboratory reliability of mouse behaviour recorded in home-cage and open-field.

    Science.gov (United States)

    Robinson, Lianne; Spruijt, Berry; Riedel, Gernot

    2018-04-15

    Reproducibility of behavioural findings between laboratories is difficult due to behaviour being sensitive to environmental factors and interactions with genetics. The objective of this study was to investigate reproducibility of behavioural data between laboratories using the PhenoTyper home cage observation system and within laboratory reproducibility using different lighting regimes. The ambulatory activity of C57BL/6 and DBA/2 mice was tested in PhenoTypers in two laboratories under near identical housing and testing conditions (Exp. 1). Additionally activity and anxiety were also assessed in the open-field test. Furthermore, testing in either a normal or inverted light/dark cycle was used to determine effects of lighting regime in a within-laboratory comparison in Aberdeen (Exp. 2). Using the PhenoTyper similar circadian rhythms were observed across laboratories. Higher levels of baseline and novelty-induced activity were evident in Aberdeen compared to Utrecht although strain differences were consistent between laboratories. Open field activity was also similar across laboratories whereas strain differences in anxiety were different. Within laboratory analysis of different lighting regimes revealed that behaviour of the mice was sensitive to changes in lighting. Utilisation of a home cage observation system facilitates the reproducibility of activity but not anxiety-related behaviours across laboratories by eliminating environmental factors known to influence reproducibility in standard behavioural tests. Standardisation of housing/test conditions resulted in reproducibility of home cage and open field activity but not anxiety-related phenotypes across laboratories with some behaviours more sensitive to environmental factors. Environmental factors include lighting and time of day. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. High-magnetic-field research collaborations

    International Nuclear Information System (INIS)

    Goettee, J.

    1998-01-01

    This is the final report of a two-year, Laboratory Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). The purpose of this project was to develop collaborations with the academic community to exploit scientific research potential of the pulsed magnetic fields that might be possible with electrically pulsed devices, as well as magneto-cumulative generators. The author started with a campaign of experiments using high-explosive-driven flux compression generators. The campaign's objective was to explore completely novel ideas in condensed-matter physics and chemistry. The initiative was very successful in pulling together top researchers from around the world

  16. Spectroscopic investigation of species separation in opening switch plasmas

    Science.gov (United States)

    Jackson, S. L.; Phipps, D. G.; Richardson, A. S.; Commisso, R. J.; Hinshelwood, D. D.; Murphy, D. P.; Schumer, J. W.; Weber, B. V.; Boyer, C. N.; Doron, R.; Biswas, S.; Maron, Y.

    2015-11-01

    Interactions between magnetic fields and current-carrying plasmas that lead to the separation of plasma species in multi-species plasmas are being studied in a plasma opening switch geometry. Several Marshall guns are used to inject single or multi-species plasmas between coaxial conductors connected to the output of the Naval Research Laboratory's Hawk pulsed-power generator. Following injection of the plasma, the generator is used at roughly half power to apply an electrical pulse with a peak current of 450 kA, a peak voltage of 400 kV, and a rise time of 1.2 μs. The resulting magnetic field interacts with the plasma through a combination of field penetration and magnetohydrodynamic (MHD) pushing that is not well understood but can lead to the separation of plasma species in multi-species plasmas. An ICCD-coupled spectrometer has been used in combination with magnetic probes, a ribbon-beam interferometer, and particle-in-cell (PIC) modeling to diagnose and understand conditions in the plasma from the time it is injected until the end of the conduction phase of the opening switch. This work supported by the Naval Research Laboratory Base Program and the Office of Naval Research.

  17. A Comprehensive Literature Review of the ERP research field

    DEFF Research Database (Denmark)

    Kræmmergaard, Pernille; Schlichter, Bjarne Rerup

    During the past decade ERP has attracted attention from both academic and industrial communities (Shehab, Sharp et al. 2004) and we feel that now is an opportune time for the ERP field to ask how the field has evolved and what its present state is (Chen and Hirschheim 2004). The purpose...... of this paper is to address these questions, which is done by providing an overview of the Enterprise Resource Planning (ERP) research field regardless of research discipline, research topic and research traditions. Abstracts from 723 peer-reviewed journal publications from 2000 up till 2007 have been analyzed...... according to journal, authors and year of publication, and further categorized into research discipline, research topic and methods used. The paper demonstrates that the body of academic knowledge about ERP systems has reached a certain level of maturity and several different research disciplines have...

  18. Oval gradient coils for an open magnetic resonance imaging system with a vertical magnetic field.

    Science.gov (United States)

    Matsuzawa, Koki; Abe, Mitsushi; Kose, Katsumi; Terada, Yasuhiko

    2017-05-01

    Existing open magnetic resonance imaging (MRI) systems use biplanar gradient coils for the spatial encoding of signals. We propose using novel oval gradient coils for an open vertical-field MRI. We designed oval gradients for a 0.3T open MRI system and showed that such a system could outperform a traditional biplanar gradient system while maintaining adequate gradient homogeneity and subject accessibility. Such oval gradient coils would exhibit high efficiency, low inductance and resistance, and high switching capability. Although the designed oval Y and Z coils showed more heat dissipation and less cooling capability than biplanar coils with the same gap, they showed an efficient heat-dissipation path to the surrounding air, which would alleviate the heat problem. The performance of the designed oval-coil system was demonstrated experimentally by imaging a human hand. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. Applying open source innovation approaches in developing business innovation

    DEFF Research Database (Denmark)

    Aagaard, Annabeth; Lindgren, Peter

    2015-01-01

    and managed effectively in developing business model innovation. The aim of this paper is therefore to close this research gap and to provide new knowledge within the research field of OI and OI applications. Thus, in the present study we explore the facilitation and management of open source innovation...... in developing business model innovation in the context of an international OI contest across five international case companies. The findings reveal six categories of key antecedents in effective facilitation and management of OI in developing business model innovation.......More and more companies are pursuing continuous innovation through different types of open source innovation and across different partners. The growing interest in open innovation (OI) originates both from the academic community as well as amongst practitioners motivating further investigation...

  20. Open Data, Open Source and Open Standards in chemistry: The Blue Obelisk five years on

    Science.gov (United States)

    2011-01-01

    Background The Blue Obelisk movement was established in 2005 as a response to the lack of Open Data, Open Standards and Open Source (ODOSOS) in chemistry. It aims to make it easier to carry out chemistry research by promoting interoperability between chemistry software, encouraging cooperation between Open Source developers, and developing community resources and Open Standards. Results This contribution looks back on the work carried out by the Blue Obelisk in the past 5 years and surveys progress and remaining challenges in the areas of Open Data, Open Standards, and Open Source in chemistry. Conclusions We show that the Blue Obelisk has been very successful in bringing together researchers and developers with common interests in ODOSOS, leading to development of many useful resources freely available to the chemistry community. PMID:21999342

  1. Characteristics of growing media mixes and application for open-field production of strawberry (Fragaria ananassa)

    Science.gov (United States)

    Pathogen-free growing media are widely used for strawberry production in protected structures in Europe but not common in the United States. There is a need to investigate the feasibility of producing strawberry fruits in open fields with the pathogen-free media in the U.S. The objective of the stud...

  2. An Open Source-based Approach to the Development of Research Reactor Simulator

    International Nuclear Information System (INIS)

    Joo, Sung Moon; Suh, Yong Suk; Park, Cheol Park

    2016-01-01

    In reactor design, operator training, safety analysis, or research using a reactor, it is essential to simulate time dependent reactor behaviors such as neutron population, fluid flow, and heat transfer. Furthermore, in order to use the simulator to train and educate operators, a mockup of the reactor user interface is required. There are commercial software tools available for reactor simulator development. However, it is costly to use those commercial software tools. Especially for research reactors, it is difficult to justify the high cost as regulations on research reactor simulators are not as strict as those for commercial Nuclear Power Plants(NPPs). An open source-based simulator for a research reactor is configured as a distributed control system based on EPICS framework. To demonstrate the use of the simulation framework proposed in this work, we consider a toy example. This example approximates a 1-second impulse reactivity insertion in a reactor, which represents the instantaneous removal and reinsertion of a control rod. The change in reactivity results in a slightly delayed change in power and corresponding increases in temperatures throughout the system. We proposed an approach for developing research reactor simulator using open source software tools, and showed preliminary results. The results demonstrate that the approach presented in this work can provide economical and viable way of developing research reactor simulators

  3. A target field design of open multi-purpose RF coil for musculoskeletal MR imaging at 3T.

    Science.gov (United States)

    Gao, Fei; Zhang, Rui; Zhou, Diange; Wang, Xiaoying; Huang, Kefu; Zhang, Jue

    2016-10-01

    Musculoskeletal MR imaging under multi-angle situations plays an increasingly important role in assessing joint and muscle tissues system. However, there are still limitations due to the closed structures of most conventional RF coils. In this study, a time-harmonic target-field method was employed to design open multi-purpose coil (OMC) for multi-angle musculoskeletal MR imaging. The phantom imaging results suggested that the proposed OMC could achieve homogeneously distributed magnetic field and high signal-to-noise ratio (SNR) of 239.04±0.83 in the region of interest (ROI). The maximum temperature in the heating hazard test was 16°C lower than the standard regulation, which indicated the security of the designed OMC. Furthermore, to demonstrate the effectiveness of the proposed OMC for musculoskeletal MR imaging, especially for multi-angle imaging, a healthy volunteer was examined for MR imaging of elbow, ankle and knee using OMC. The in vivo imaging results showed that the proposed OMC is effective for MR imaging of musculoskeletal tissues at different body parts, with satisfied B1 field homogeneity and SNR. Moreover, the open structure of the OMC could provide a large joint movement region. The proposed open multi-purpose coil is feasible for musculoskeletal MR imaging, and potentially, it is more suitable for the evaluation of musculoskeletal tissues under multi-angle conditions. Copyright © 2016. Published by Elsevier Inc.

  4. Annual tendency of research papers used ICR mice as experimental animals in biomedical research fields.

    Science.gov (United States)

    Kim, Ji Eun; Nam, Jung Hoon; Cho, Joon Young; Kim, Kil Soo; Hwang, Dae Youn

    2017-06-01

    Institute of Cancer Research (ICR) mice have been widely used in various research fields including toxicology, oncology, pharmacology, and pharmaceutical product safety testing for decades. However, annual tendency of research papers involving ICR mice in various biomedical fields has not been previously analyzed. In this study, we examined the numbers of papers that used ICR mice as experimental animals in the social science, natural science, engineering, medicine-pharmacy, marine agriculture-fishery, and art-kinesiology fields by analyzing big data. Numbers of ICR mouse-used papers gradually increased from 1961 to 2014, but small decreases were observed in 2015 and 2016. The largest number of ICR-used papers were published in the medicine-pharmacy field, followed by natural science and art-kinesiology fields. There were no ICR mouse-used papers in other fields. Furthermore, ICR mice have been widely employed in cell biology studies within the natural science field as well as in biochemistry and pathology in the medicine-pharmacy field. Few ICR mouse-used papers were published in exercise biochemistry and exercise nutrition in the art-kinesiology field. Regardless in most fields, the total numbers of published papers involving ICR mice were higher in 2014 than in other years, although the numbers in some fields including dentistry, veterinary science, and dermatology were high in 2016. Taken together, the present study shows that various ICR stocks, including Korl:ICR mice, are widely employed as experimental animals in various biomedical research fields.

  5. Status of open access in the biomedical field in 2005.

    Science.gov (United States)

    Matsubayashi, Mamiko; Kurata, Keiko; Sakai, Yukiko; Morioka, Tomoko; Kato, Shinya; Mine, Shinji; Ueda, Shuichi

    2009-01-01

    This study was designed to document the state of open access (OA) in the biomedical field in 2005. PubMed was used to collect bibliographic data on target articles published in 2005. PubMed, Google Scholar, Google, and OAIster were then used to establish the availability of free full text online for these publications. Articles were analyzed by type of OA, country, type of article, impact factor, publisher, and publishing model to provide insight into the current state of OA. Twenty-seven percent of all the articles were accessible as OA articles. More than 70% of the OA articles were provided through journal websites. Mid-rank commercial publishers often provided OA articles in OA journals, while society publishers tended to provide OA articles in the context of a traditional subscription model. The rate of OA articles available from the websites of individual authors or in institutional repositories was quite low. In 2005, OA in the biomedical field was achieved under an umbrella of existing scholarly communication systems. Typically, OA articles were published as part of subscription journals published by scholarly societies. OA journals published by BioMed Central contributed to a small portion of all OA articles.

  6. Quantarctica: A Unique, Open, Standalone GIS Package for Antarctic Research and Education

    Science.gov (United States)

    Roth, George; Matsuoka, Kenichi; Skoglund, Anders; Melvær, Yngve; Tronstad, Stein

    2017-04-01

    The Norwegian Polar Institute has developed Quantarctica (http://quantarctica.npolar.no), an open GIS package for use by the international Antarctic community. Quantarctica includes a wide range of cartographic basemap layers, geophysical and glaciological datasets, and satellite imagery in standardized open file formats with a consistent Antarctic map projection and customized layer and labeling styles for quick, effective cartography. Quantarctica's strengths as an open science platform lie in 1) The complete, ready-to-use data package which includes full-resolution, original-quality vector and raster data, 2) A policy for freely-redistributable and modifiable data including all metadata and citations, and 3) QGIS, a free, full-featured, modular, offline-capable open-source GIS suite with a rapid and active development and support community. The Quantarctica team is actively incorporating more up-to-date, peer-reviewed, freely distributable pan-Antarctic geospatial datasets for the next version release in 2017. As part of this ongoing development, we are investigating the best approaches for quickly and seamlessly distributing new and updated data to users, storing datasets in efficient, open file formats while maintaining full data integrity, and coexisting with numerous online data portals in a way that most actively benefits the Antarctic community. A recent survey of Quantarctica users showed broad geographical adoption among Antarctic Treaty countries, including those outside the large US and UK Antarctic programs. Maps and figures produced by Quantarctica have also appeared in open-access journals and outside of the formal scientific community on popular science and GIS blogs. Our experience with the Quantarctica project has shown the tremendous value of education and outreach, not only in promoting open software, data formats, and practices, but in empowering Antarctic science groups to more effectively use GIS and geospatial data. Open practices are

  7. Four factors underlying mouse behavior in an open field.

    Science.gov (United States)

    Tanaka, Shoji; Young, Jared W; Halberstadt, Adam L; Masten, Virginia L; Geyer, Mark A

    2012-07-15

    The observation of the locomotor and exploratory behaviors of rodents in an open field is one of the most fundamental methods used in the field of behavioral pharmacology. A variety of behaviors can be recorded automatically and can readily generate a multivariate pattern of pharmacological effects. Nevertheless, the optimal ways to characterize observed behaviors and concomitant drug effects are still under development. The aim of this study was to extract meaningful behavioral factors that could explain variations in the observed variables from mouse exploration. Behavioral data were recorded from male C57BL/6J mice (n=268) using the Behavioral Pattern Monitor (BPM). The BPM data were subjected to the exploratory factor analysis. The factor analysis extracted four factors: activity, sequential organization, diversive exploration, and inspective exploration. The activity factor and the two types of exploration factors correlated positively with one another, while the sequential organization factor negatively correlated with the remaining factors. The extracted factor structure constitutes a behavioral model of mouse exploration. This model will provide a platform on which one can assess the effects of psychoactive drugs and genetic manipulations on mouse exploratory behavior. Further studies are currently underway to examine the factor structure of similar multivariate data sets from humans tested in a human BPM. Copyright © 2012 Elsevier B.V. All rights reserved.

  8. For the Public Good: Research Impact and the Promise of Open Access

    OpenAIRE

    DePauw, Karen P.; Seyam, Mohammed; Roy, Siddhartha; Abbas, Montasir; Hole, Brian; Potter, Peter

    2016-01-01

    As a land-grant institution, Virginia Tech is committed to research that meaningfully engages with the vital concerns of our day such as feeding, building, and empowering a healthy world. How does Virginia Tech’s commitment to engagement fit with the Open Access vision for unrestricted online access to scholarly research? Have OA journals, public repositories, and federal mandates simply made a researcher’s life more complicated or could OA be the key to unlocking research impact on a global ...

  9. Open magnetic fields and the solar cycle. Pt. 1

    International Nuclear Information System (INIS)

    Levine, R.H.

    1982-01-01

    Models of open magnetic structures on the Sun are presented for periods near solar minimum (CR 1626-1634) and near solar maximum (CR 1668-1678). Together with previous models of open magnetic structures during the declining phase (CR 1601-1611) these calculations provide clues to the relations between open structures, coronal holes, and active regions at different times of the solar cycle. Near solar minimum the close relation between active regions and open structures does not exist. It is suggested that near solar minimum the systematic emergence of new flux with the proper polarity imbalance to maintain open magnetic structures may occur primarily at very small spatial scales. Near solar maximum the role of active regions in maintaining open structures and coronal holes is strong, with large active regions emerging in the proper location and orientation to maintain open structures longer than typical active region lifetimes. Although the use of He I 10830 A spectroheliograms as a coronal hole indicator is shown to be subject to significant ambiguity, the agreement between calculated open structures and coronal holes determined from He I 10830 A spectroheliograms is very good. The rotation properties of calculated open structures near solar maximum strongly suggest two classes of features: one that rotates differentially similar to sunspots and active regions and a separate class that rotates more rigidly, as was the case for single large coronal holes during Skylab. (orig.)

  10. Exploratory rearing: a context- and stress-sensitive behavior recorded in the open-field test.

    Science.gov (United States)

    Sturman, Oliver; Germain, Pierre-Luc; Bohacek, Johannes

    2018-02-16

    Stressful experiences are linked to anxiety disorders in humans. Similar effects are observed in rodent models, where anxiety is often measured in classic conflict tests such as the open-field test. Spontaneous rearing behavior, in which rodents stand on their hind legs to explore, can also be observed in this test yet is often ignored. We define two forms of rearing, supported rearing (in which the animal rears against the walls of the arena) and unsupported rearing (in which the animal rears without contacting the walls of the arena). Using an automated open-field test, we show that both rearing behaviors appear to be strongly context dependent and show clear sex differences, with females rearing less than males. We show that unsupported rearing is sensitive to acute stress, and is reduced under more averse testing conditions. Repeated testing and handling procedures lead to changes in several parameters over varying test sessions, yet unsupported rearing appears to be rather stable within a given animal. Rearing behaviors could therefore provide an additional measure of anxiety in rodents relevant for behavioral studies, as they appear to be highly sensitive to context and may be used in repeated testing designs.

  11. Maternal enrichment affects prenatal hippocampal proliferation and open-field behaviors in female offspring mice.

    Science.gov (United States)

    Maruoka, Takashi; Kodomari, Ikuko; Yamauchi, Rena; Wada, Etsuko; Wada, Keiji

    2009-04-17

    The maternal environment is thought to be important for fetal brain development. However, the effects of maternal environment are not fully understood. Here, we investigated whether enrichment of the maternal environment can influence prenatal brain development and postnatal behaviors in mice. An enriched environment is a housing condition with several objects such as a running wheel, tube and ladder, which are thought to increase sensory, cognitive and motor stimulation in rodents compared with standard housing conditions. First, we measured the number of BrdU-positive cells in the hippocampal dentate gyrus of fetuses from pregnant dams housed in an enriched environment. Our results revealed that maternal enrichment influences cell proliferation in the hippocampus of female, but not male, fetuses. Second, we used the open-field test to investigate postnatal behaviors in the offspring of dams housed in the enriched environment during pregnancy. We found that maternal enrichment significantly affects the locomotor activity and time spent in the center of the open-field in female, but not male, offspring. These results indicate that maternal enrichment influences prenatal brain development and postnatal behaviors in female offspring.

  12. The Peer Reviewers’ Openness Initiative: Incentivizing open research practices through peer review

    NARCIS (Netherlands)

    R.D. Morey (Richard D.); C.D. Chambers (Christopher D.); P.J. Etchells (Peter J.); C.R. Harris (Christine R.); R. Hoekstra (Rink); D. Lakens (Daniël); S. Lewandowsky (Stephan); C.C. Morey (Candice Coker); D.P. Newman (Daniel P.); F.D. Schönbrodt (Felix D.); W. Vanpaemel (Wolf); E.J. Wagenmakers (Eric-Jan); R.A. Zwaan (Rolf)

    2016-01-01

    textabstractOpenness is one of the central values of science. Open scientific practices such as sharing data, materials and analysis scripts alongside published articles have many benefits, including easier replication and extension studies, increased availability of data for theory-building and

  13. Open Source Opens Doors: Repurposing Library Software to Facilitate Faculty Research and Collaboration

    Directory of Open Access Journals (Sweden)

    Sandra L. Stump

    2013-10-01

    Full Text Available Normal 0 false false false EN-US X-NONE X-NONE Asked to convert a faculty-created Microsoft Word document of biblical references found within popular films into a searchable database for scholars, the Albright College library staff helped create a multi-access database called Bible in the Reel World. The database relied on student workers for inputting data, used MARC standard formatting for future portability, and encouraged interactive feedback, enabling scholars to submit comments and suggest additional films and references. Using the open source integrated library system Koha, MarcEdit software, and free record exporting from IMDb, library staff created a fully-searchable database for researchers and scholars to examine the use of scripture in popular film.

  14. Exposure to an open-field arena increases c-Fos expression in a distributed anxiety-related system projecting to the basolateral amygdaloid complex.

    Science.gov (United States)

    Hale, M W; Hay-Schmidt, A; Mikkelsen, J D; Poulsen, B; Shekhar, A; Lowry, C A

    2008-08-26

    Anxiety states and anxiety-related behaviors appear to be regulated by a distributed and highly interconnected system of brain structures including the basolateral amygdala. Our previous studies demonstrate that exposure of rats to an open-field in high- and low-light conditions results in a marked increase in c-Fos expression in the anterior part of the basolateral amygdaloid nucleus (BLA) compared with controls. The neural mechanisms underlying the anatomically specific effects of open-field exposure on c-Fos expression in the BLA are not clear, however, it is likely that this reflects activation of specific afferent input to this region of the amygdala. In order to identify candidate brain regions mediating anxiety-induced activation of the basolateral amygdaloid complex in rats, we used cholera toxin B subunit (CTb) as a retrograde tracer to identify neurons with direct afferent projections to this region in combination with c-Fos immunostaining to identify cells responding to exposure to an open-field arena in low-light (8-13 lux) conditions (an anxiogenic stimulus in rats). Adult male Wistar rats received a unilateral microinjection of 4% CTb in phosphate-buffered saline into the basolateral amygdaloid complex. Rats were housed individually for 11 days after CTb injections and handled (HA) for 2 min each day. On the test day rats were either, 1) exposed to an open-field in low-light conditions (8-13 lux) for 15 min (OF); 2) briefly HA or 3) left undisturbed (control). We report that dual immunohistochemical staining for c-Fos and CTb revealed an increase in the percentage of c-Fos-immunopositive basolateral amygdaloid complex-projecting neurons in open-field-exposed rats compared with HA and control rats in the ipsilateral CA1 region of the ventral hippocampus, subiculum and lateral entorhinal cortex. These data are consistent with the hypothesis that exposure to the open-field arena activates an anxiety-related neuronal system with convergent input to the

  15. Gap opening and tuning in single-layer graphene with combined electric and magnetic field modulation

    Institute of Scientific and Technical Information of China (English)

    Lin Xin; Wang Hai-Long; Pan Hui; Xu Huai-Zhe

    2011-01-01

    The energy band structure of single-layer graphene under one-dimensional electric and magnetic field modulation is theoretically investigated. The criterion for bandgap opening at the Dirac point is analytically derived with a two-fold degeneracy second-order perturbation method. It is shown that a direct or an indirect bandgap semiconductor could be realized in a single-layer graphene under some specific configurations of the electric and magnetic field arrangement. Due to the bandgap generated in the single-layer graphene, the Klein tunneling observed in pristine graphene is completely suppressed.

  16. Open Access Publishing: A Study of Current Practice in Oral and Maxillofacial Surgery Research.

    Science.gov (United States)

    Tahim, Arpan; Bansal, Hitesh; Goodson, Alexander M C; Payne, Karl F B; Sabharwal, Sanjeeve

    2016-12-01

    Open access (OA) publication has become an increasingly common route for dissemination of scientific research findings. However, it remains a contentious issue with continued debate as to its impact on the peer-review process and a potential change in the quality of subsequent evidence published. There is little research that looks into OA in oral and maxillofacial surgery. We investigated the OA policy in the 30 relevant journals listed in the Institute for Scientific Information Web of Knowledge journal citation report, comparing bibliometric data and quality of evidence produced in journals offering OA and those with subscription-only policies. 3474 articles were graded for evidence level and the results correlated to journal OA status. 76.7 % of journals offered authors OA services. There was no difference between impact factor, self-citation rate, total citations or quality of evidence between OA and subscription journals. These findings should send clear messages to both clinicians and researchers and should re- assure readers that scientific findings that are disseminated in open access form do not differ in quality to those in subscription-only format. It should reinforce that open access formats are a credible way to display research findings in oral and maxillofacial surgery.

  17. Manual versus Automated Rodent Behavioral Assessment: Comparing Efficacy and Ease of Bederson and Garcia Neurological Deficit Scores to an Open Field Video-Tracking System.

    Science.gov (United States)

    Desland, Fiona A; Afzal, Aqeela; Warraich, Zuha; Mocco, J

    2014-01-01

    Animal models of stroke have been crucial in advancing our understanding of the pathophysiology of cerebral ischemia. Currently, the standards for determining neurological deficit in rodents are the Bederson and Garcia scales, manual assessments scoring animals based on parameters ranked on a narrow scale of severity. Automated open field analysis of a live-video tracking system that analyzes animal behavior may provide a more sensitive test. Results obtained from the manual Bederson and Garcia scales did not show significant differences between pre- and post-stroke animals in a small cohort. When using the same cohort, however, post-stroke data obtained from automated open field analysis showed significant differences in several parameters. Furthermore, large cohort analysis also demonstrated increased sensitivity with automated open field analysis versus the Bederson and Garcia scales. These early data indicate use of automated open field analysis software may provide a more sensitive assessment when compared to traditional Bederson and Garcia scales.

  18. Manual versus Automated Rodent Behavioral Assessment: Comparing Efficacy and Ease of Bederson and Garcia Neurological Deficit Scores to an Open Field Video-Tracking System

    Directory of Open Access Journals (Sweden)

    Fiona A. Desland

    2014-01-01

    Full Text Available Animal models of stroke have been crucial in advancing our understanding of the pathophysiology of cerebral ischemia. Currently, the standards for determining neurological deficit in rodents are the Bederson and Garcia scales, manual assessments scoring animals based on parameters ranked on a narrow scale of severity. Automated open field analysis of a live-video tracking system that analyzes animal behavior may provide a more sensitive test. Results obtained from the manual Bederson and Garcia scales did not show significant differences between pre- and post-stroke animals in a small cohort. When using the same cohort, however, post-stroke data obtained from automated open field analysis showed significant differences in several parameters. Furthermore, large cohort analysis also demonstrated increased sensitivity with automated open field analysis versus the Bederson and Garcia scales. These early data indicate use of automated open field analysis software may provide a more sensitive assessment when compared to traditional Bederson and Garcia scales.

  19. Open Data and Open Science for better Research in the Geo and Space Domain

    Science.gov (United States)

    Ritschel, B.; Seelus, C.; Neher, G.; Iyemori, T.; Koyama, Y.; Yatagai, A. I.; Murayama, Y.; King, T. A.; Hughes, S.; Fung, S. F.; Galkin, I. A.; Hapgood, M. A.; Belehaki, A.

    2015-12-01

    Main open data principles had been worked out in the run-up and finally adopted in the Open Data Charta at the G8 summit in Lough Erne, Northern Ireland in June 2013. Important principles are also valid for science data, such as Open Data by Default, Quality and Quantity, Useable by All, Releasing Data for Improved Governance, Releasing Data for Innovation. There is also an explicit relationship to such areas of high values as earth observation, education and geospatial data. The European union implementation plan of the Open Data Charta identifies among other things objectives such as making data available in an open format, enabling semantic interoperability, ensuring quality, documentation and where appropriate reconciliation across different data sources, implementing software solutionsallowing easy management, publication or visualization of datasets and simplifying clearance of intellectual property rights.Open Science is not just a list of already for a longer time known principles but stands for a lot of initiatives and projects around a better handling of scientific data and openly shared scientific knowledge. It is also about transparency in methodology and collection of data, availability and reuse of scientific data, public accessibility to scientific communication and using of social media to facility scientific collaboration. Some projects are concentrating on open sharing of free and open source software and even further hardware in kind of processing capabilities. In addition question about the mashup of data and publication and an open peer review process are addressed.Following the principles of open data and open science the newest results of the collaboration efforts in mashing up the data servers related to the Japanese IUGONET, the European Union ESPAS and the GFZ ISDC semantic Web projects will be presented here. The semantic Web based approach for the mashup is focusing on the design and implementation of a common but still distributed data

  20. The Peer Reviewers’ Openness Initiative: Incentivising Open Research Practices through Peer Review

    NARCIS (Netherlands)

    Morey, Richard D.; Chambers, Christopher D.; Etchells, Peter J.; Harris, Christine R; Hoekstra, Rink; Lakens, Daniël; Lewandowsky, Stephan; Morey, Candice Coker; Newman, Daniel P.; Schönbrodt, Felix; Vanpaemel, Wolf; Wagenmakers, Eric-Jan; Zwaan, Rolf A.

    2016-01-01

    Openness is one of the central values of science. Open scientific practices such as sharing data, materials, and analysis scripts alongside published articles have many benefits, including easier replication and extension studies, increased availability of data for theory-building and meta-analysis,

  1. The peer reviewers' openness initiative : incentivizing open research practices through peer review

    NARCIS (Netherlands)

    Morey, R.; Chambers, C.; Etchells, P.; Harris, C.; Hoekstra, R.; Lakens, D.; Lewandowsky, S.; Morey, C.; Newman, D.; Schönbrodt, F.; Vanpaemel, W.; Wagenmakers, E.-J.; Zwaan, R.

    2016-01-01

    Openness is one of the central values of science. Open scientific practices such as sharing data, materials and analysis scripts alongside published articles have many benefits, including easier replication and extension studies, increased availability of data for theory-building and meta-analysis,

  2. The Peer Reviewers’ Openness Initiative : incentivizing open research practices through peer review

    NARCIS (Netherlands)

    Morey, R.D.; Chambers, C.D.; Etchells, P.J.; Harris, C.R.; Hoekstra, R.; Lakens, D.; Lewandowsky, S.; Morey, C.C.; Newman, D.P.; Schönbrodt, F.D.; Vanpaemel, W.; Wagenmakers, E.-J.; Zwaan, R.A.

    2016-01-01

    Openness is one of the central values of science. Open scientific practices such as sharing data, materials and analysis scripts alongside published articles have many benefits, including easier replication and extension studies, increased availability of data for theory-building and meta-analysis,

  3. Early deprivation increases high-leaning behavior, a novel anxiety-like behavior, in the open field test in rats.

    Science.gov (United States)

    Kuniishi, Hiroshi; Ichisaka, Satoshi; Yamamoto, Miki; Ikubo, Natsuko; Matsuda, Sae; Futora, Eri; Harada, Riho; Ishihara, Kohei; Hata, Yoshio

    2017-10-01

    The open field test is one of the most popular ethological tests to assess anxiety-like behavior in rodents. In the present study, we examined the effect of early deprivation (ED), a model of early life stress, on anxiety-like behavior in rats. In ED animals, we failed to find significant changes in the time spent in the center or thigmotaxis area of the open field, the common indexes of anxiety-like behavior. However, we found a significant increase in high-leaning behavior in which animals lean against the wall standing on their hindlimbs while touching the wall with their forepaws at a high position. The high-leaning behavior was decreased by treatment with an anxiolytic, diazepam, and it was increased under intense illumination as observed in the center activity. In addition, we compared the high-leaning behavior and center activity under various illumination intensities and found that the high-leaning behavior is more sensitive to illumination intensity than the center activity in the particular illumination range. These results suggest that the high-leaning behavior is a novel anxiety-like behavior in the open field test that can complement the center activity to assess the anxiety state of rats. Copyright © 2017 Elsevier Ireland Ltd and Japan Neuroscience Society. All rights reserved.

  4. Research field of fire technology in Finland

    Science.gov (United States)

    Loikkanen, P.; Holm, C.

    1987-02-01

    The goal of the study is to give an overview of the whole diversified research field of fire technology and its problems. For this reason the research subjects have been grouped so that the responsibilities of different authorities, the legislation and specifications, various fields of technology, areas of industry, and groups of products could all be found as clearly as possible. The field has been divided into nine sub-areas. They are: general grounds, fire physics and chemistry, structural fire prevention, textiles and furnishings, devices for heating and other use, detection, fire fighting and rescue, quality control, and special problems. The sub-areas have been divided into 34 main subjects and these, excluding those of special problems, further into as many as 117 subject groups. Characteristics and problems of the sub-areas and the main subjects have been described. The subject groups have been characterized by key words and concepts which outline the projects. No concrete research projects and programs have, however, been directly suggested because their extent and contents depend essentially on financing and other available resources.

  5. Lithium ameliorates open-field and elevated plus maze behaviors, and brain phospho-glycogen synthase kinase 3-beta expression in fragile X syndrome model mice.

    Science.gov (United States)

    Chen, Xi; Sun, Weiwen; Pan, Ying; Yang, Quan; Cao, Kaiyi; Zhang, Jin; Zhang, Yizhi; Chen, Mincong; Chen, Feidi; Huang, Yueling; Dai, Lijun; Chen, Shengqiang

    2013-10-01

    To investigate whether lithium modifies open-field and elevated plus maze behavior, and brain phospho-glycogen synthase kinase 3 (P-GSK3beta) expression in Fmr1 knockout mice. One hundred and eighty FVB mice, including knockout and wild type, with an age of 30 days were used. An open-field and elevated plus maze was utilized to test behavior, while western blot was used to measure the P-GSK3beta expression. Six groups were formed: control (saline), lithium chloride 30, 60, 90, 120, and 200 mg/kg. The experiments were carried out in the Institute of Neuroscience, Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China between January and June 2012. Lithium significantly decreased total distance, crossing, central area time, and center entry in the open-field test (popen-arm tracking, open-arm entry, and open-arm time in the elevated plus maze (popen-field and elevated plus maze behaviors of Fmr1 knockout mice. This effect may be related to its enhancement of P-GSK3beta expression. Our findings suggest that lithium might have a therapeutic effect in fragile X syndrome.

  6. From anonymity to "open doors": IRB responses to tensions with researchers.

    Science.gov (United States)

    Klitzman, Robert

    2012-07-03

    Tensions between IRBs and researchers in the US and elsewhere have increased, and may affect whether, how, and to what degree researchers comply with ethical guidelines. Yet whether, how, when, and why IRBs respond to these conflicts have received little systematic attention. I contacted 60 US IRBs (every fourth one in the list of the top 240 institutions by NIH funding), and interviewed leaders from 34 (response rate = 55%) and an additional 12 members and administrators. IRBs often try to respond to tensions with researchers and improve relationships in several ways, but range widely in how, when, and to what degree (e.g., in formal and informal structure, content, and tone of interactions). IRBs varied from open and accessible to more distant and anonymous, and in the amount and type of "PR work" and outreach they do. Many boards seek to improve the quantity, quality, and helpfulness of communication with PIs, but differ in how. IRBs range in meetings from open to closed, and may have clinics and newsletters. Memos can vary in helpfulness and tone (e.g., using "charm"). IRBs range considerably, too, in the degrees to which they seek to educate PIs, showing them the underlying ethical principles. But these efforts take time and resources, and IRBs thus vary in degrees of responses to PI complaints. This study, the first to explore the mechanisms through which IRBs respond to tensions and interactions with PIs, suggests that these committees seek to respond to conflicts with PIs in varying ways - both formal and informal, involving both the form and content of communications. This study has important implications for future practice, research, and policy, suggesting needs for increased attention to not only what IRBs communicate to PIs, but how (i.e., the tone and the nature of interactions). IRBs can potentially improve relationships with PIs in several ways: using more "open doors" rather than anonymity, engaging in outreach (e.g., through clinics), enhancing

  7. The Ecology of the Open Practitioner: A Conceptual Framework for Open Research

    Science.gov (United States)

    Stagg, Adrian

    2017-01-01

    Open Educational Practices (OEP) have gained traction internationally over the last fifteen years, with individuals, institutions, and governments increasingly interested in the affordances of openness. Whilst initiatives, policies, and support mechanisms are evident, there is an ever-present danger of localised contexts being unintentionally…

  8. The Research and Implementation of MUSER CLEAN Algorithm Based on OpenCL

    Science.gov (United States)

    Feng, Y.; Chen, K.; Deng, H.; Wang, F.; Mei, Y.; Wei, S. L.; Dai, W.; Yang, Q. P.; Liu, Y. B.; Wu, J. P.

    2017-03-01

    It's urgent to carry out high-performance data processing with a single machine in the development of astronomical software. However, due to the different configuration of the machine, traditional programming techniques such as multi-threading, and CUDA (Compute Unified Device Architecture)+GPU (Graphic Processing Unit) have obvious limitations in portability and seamlessness between different operation systems. The OpenCL (Open Computing Language) used in the development of MUSER (MingantU SpEctral Radioheliograph) data processing system is introduced. And the Högbom CLEAN algorithm is re-implemented into parallel CLEAN algorithm by the Python language and PyOpenCL extended package. The experimental results show that the CLEAN algorithm based on OpenCL has approximately equally operating efficiency compared with the former CLEAN algorithm based on CUDA. More important, the data processing in merely CPU (Central Processing Unit) environment of this system can also achieve high performance, which has solved the problem of environmental dependence of CUDA+GPU. Overall, the research improves the adaptability of the system with emphasis on performance of MUSER image clean computing. In the meanwhile, the realization of OpenCL in MUSER proves its availability in scientific data processing. In view of the high-performance computing features of OpenCL in heterogeneous environment, it will probably become the preferred technology in the future high-performance astronomical software development.

  9. Heritability of feather pecking and open-field response of laying hens at two different ages

    NARCIS (Netherlands)

    Rodenburg, T.B.; Buitenhuis, A.J.; Ask, B.; Uitdehaag, K.A.; Koene, P.; Poel, van der J.J.; Bovenhuis, H.

    2003-01-01

    The objective of the current study was to estimate heritabilities. (h(2)) of feather pecking and open-field response of laying hens at two different ages. An F-2 cross, originating from a high and a low feather pecking line of laying hens, was used for the experiment. Each of the 630 birds of the

  10. Project-based knowledge in organizing open innovation

    CERN Document Server

    Comacchio, Anna; Pizzi, Claudio

    2014-01-01

    Enriching understanding of the current theoretical debate on project-based open innovation, ‘Project-based Knowledge in Organizing Open Innovation’ draws on innovation management literature and knowledge-based perspectives to investigate the relationship between knowledge development at project level and the strategic organization of open innovation. Addressing the still open issue of how the firm level should be complemented by studies at the project level of analysis, this book provides theoretical and empirical arguments on the advantages of a more fine-grained level of analysis to understand how firms organize their innovation processes across boundaries. The book also addresses the emerging interest in the management literature on project-based organizations, and on the relevance of project forms of organizing in a knowledge-based economy. Through field research in different industrial settings , this book provides empirical evidence on how firms design open innovation project-by-project and it will ...

  11. International Permafrost Field Courses in Siberia: the Synthesis of Research and Education

    Science.gov (United States)

    Ablyazina, D.; Boitsov, A.; Grebenets, V.; Kaverin, D.; Klene, A.; Kurchatova, A.; Pfeiffer, E. M.; Zschocke, A.; Shiklomanov, N.; Streletskiy, D.

    2009-04-01

    . Specific emphasis was made on the study of permafrost soils. Throughout the course students were exposed to a wide range of field techniques, including surveying, coring, geothermal monitoring, thaw-depth measurements, landscape characterization, geomorphologic investigations, soil description and classification according to International, Russian, German, and U.S. classification schemes, and hydrologic and botanical field investigations. Significant portion of the course curriculum was devoted to problems of industrial development in permafrost regions. Pipelines, material sites, operating gas wells, processing plants, pump stations, and permafrost engineering testing facilities associated with three major gas fields (Yamburg, Yubileinoe, and Zapolyarnoe) were visited as part of the field excursions. Several meetings with Russian gas industry executives and workers were arranged to openly discuss economic and political issues associated with GasProm activities in West Siberia. The field work was complemented by daily lectures prepared by instructors and students, covering a wide range of topics. Students also participated in active permafrost research through daily data collection and analysis activities. Analysis of the diverse data sets obtained during the course was conducted at Moscow State University, presented in a series of detailed reports. The data collected by students were contributed to the international IPY permafrost monitoring programmes. Several students have presented results of their research at the Ninth International Conference on Permafrost and other national and international scientific meetings. This presentation describes research and educational activities of the IUCP, provides results of student research, and outlines the plan for the future.

  12. Opening the research agenda for selection of hot spots for human biomonitoring research in Belgium: a participatory research project

    Directory of Open Access Journals (Sweden)

    Chovanova Hana

    2010-07-01

    Full Text Available Abstract Background In order to select priority hotspots for environment and health research in Flanders (Belgium, an open procedure was organized. Environment and health hotspots are strong polluting point sources with possible health effects for residents living in the vicinity of the hot spot. The selection procedure was part of the work of the Flemish Centre of Expertise for Environment and Health, which investigates the relation between environmental pollution and human health. The project is funded and steered by the Flemish government. Methods The involvement of other actors than merely experts is inspired by the 'analytical-deliberative' approach of the National Research Council in the United States and the extended peer community approach. These approaches stress the importance of involving different expert- and social perspectives in order to increase the knowledge base on complex issues. In the procedure used in the project a combination of expert and stakeholder input was essential. The final decision was supported by a multi-criteria analysis of expert assessment and stakeholder advice. Results The endeavour was challenging from the start because of the complicated ambition of including a diversity of actors, potential hotspots, concerns and assessment criteria, but nevertheless the procedure proved its value in both structuring and informing the decision-making process. Moreover the process gained the support of most actors participating in the process, even though the final selection could not satisfy all preferences. Conclusions Opening the research agenda exemplifies the value of inter- and transdisciplinary cooperation as well as the need for a well-structured and negotiated procedure that combines relevant factors and actors with pragmatism. The value of such a process also needs to prove itself in practice after the procedure has been completed: the tension between an ambition of openness on the one hand and a more closed

  13. Changing Approaches Towards Open Education, Innovation and Research in Tourism

    DEFF Research Database (Denmark)

    Liburd, Janne J.; Hjalager, Anne-Mette

    2010-01-01

    There is a widely held assumption that the Internet provides opportunities to rethink and reorganise the knowledge ineraction and dissemination between industry, education and research. Web 2.0 technologies are emerging as teaching and learning tools, but there is still no striking evidence...... source education in tourism are outlined. Finally, we point out collaboraborative challenges for international tourism research and teaching....... to support the above-mentioned assumption. Accordingly, the puposes of this article are to, first, discuss the challenges in tourism education and address in brief the declining role of universities as learning monopolies and their emerging role as knowledge mediators. Second, to present open innovation...

  14. Image-guided spinal injection procedures in open high-field MRI with vertical field orientation: feasibility and technical features

    Energy Technology Data Exchange (ETDEWEB)

    Streitparth, F.; Walter, T.; Wonneberger, U.; Wagner, M.; Hermann, K.G.; Hamm, B.; Teichgraeber, U. [Charite, Humboldt-Universitaet zu Berlin, Department of Radiology, Berlin (Germany); Chopra, S. [Charite-Universitaetsmedizin Berlin, Campus Virchow Klinikum, Department of General, Visceral, and Transplantation Surgery, Berlin (Germany); Wichlas, F. [Charite-Universitaetsmedizin Berlin, Campus Virchow Klinikum, Center for Musculoskeletal Surgery, Berlin (Germany)

    2010-02-15

    We prospectively evaluated the feasibility and technical features of MR-guided lumbosacral injection procedures in open high-field MRI at 1.0 T. In a CuSO{sub 4}.5H{sub 2}O phantom and five human cadaveric spines, fluoroscopy sequences (proton-density-weighted turbo spin-echo (PDw TSE), T1w TSE, T2w TSE; balanced steady-state free precession (bSSFP), T1w gradient echo (GE), T2w GE) were evaluated using two MRI-compatible 20-G Chiba-type needles. Artefacts were analysed by varying needle orientation to B{sub 0}, frequency-encoding direction and slice orientation. Image quality was described using the contrast-to-noise ratio (CNR). Subsequently, a total of 183 MR-guided nerve root (107), facet (53) and sacroiliac joint (23) injections were performed in 53 patients. In vitro, PDw TSE sequence yielded the best needle-tissue contrasts (CNR = 45, 18, 15, 9, and 8 for needle vs. fat, muscle, root, bone and sclerosis, respectively) and optimal artefact sizes (width and tip shift less than 5 mm). In vivo, PDw TSE sequence was sufficient in all cases. The acquisition time of 2 s facilitated near-real-time MRI guidance. Drug delivery was technically successful in 100% (107/107), 87% (46/53) and 87% (20/23) of nerve root, facet and sacroiliac joint injections, respectively. No major complications occurred. The mean procedure time was 29 min (range 19-67 min). MR-guided spinal injections in open high-field MRI are feasible and accurate using fast TSE sequence designs. (orig.)

  15. Increased occurrence of pesticide residues on crops grown in protected environments compared to crops grown in open field conditions.

    Science.gov (United States)

    Allen, Gina; Halsall, Crispin J; Ukpebor, Justina; Paul, Nigel D; Ridall, Gareth; Wargent, Jason J

    2015-01-01

    Crops grown under plastic-clad structures or in greenhouses may be prone to an increased frequency of pesticide residue detections and higher concentrations of pesticides relative to equivalent crops grown in the open field. To test this we examined pesticide data for crops selected from the quarterly reports (2004-2009) of the UK's Pesticide Residue Committee. Five comparison crop pairs were identified whereby one crop of each pair was assumed to have been grown primarily under some form of physical protection ('protected') and the other grown primarily in open field conditions ('open'). For each pair, the number of detectable pesticide residues and the proportion of crop samples containing pesticides were statistically compared (n=100 s samples for each crop). The mean concentrations of selected photolabile pesticides were also compared. For the crop pairings of cabbage ('open') vs. lettuce ('protected') and 'berries' ('open') vs. strawberries ('protected') there was a significantly higher number of pesticides and proportion of samples with multiple residues for the protected crops. Statistically higher concentrations of pesticides, including cypermethrin, cyprodinil, fenhexamid, boscalid and iprodione were also found in the protected crops compared to the open crops. The evidence here demonstrates that, in general, the protected crops possess a higher number of detectable pesticides compared to analogous crops grown in the open. This may be due to different pesticide-use regimes, but also due to slower rates of pesticide removal in protected systems. The findings of this study raise implications for pesticide management in protected-crop systems. Copyright © 2014 Elsevier Ltd. All rights reserved.

  16. Current status of research on power-frequency electric and magnetic fields of research

    International Nuclear Information System (INIS)

    Anon.

    1991-01-01

    Recent scientific literature has suggested a number of possible human health effects which might be associated with exposure to power frequency electric and magnetic fields. Several authoritative reviews of this subject have been published. currently, the major uncertainty and the major research effort is directed to the issue of these fields and cancer. Therefore, this review will be limited to examining the evidence relating prolonged power-frequency electric and magnetic field exposure to cancer in human populations. This paper reports that the CIGRE expert Group has assessed the research literature in the following areas: epidemiological evidence, animal studies, cellular effects, knowledge of mechanisms

  17. Open solar flux estimates from near-Earth measurements of the interplanetary magnetic field: comparison of the first two perihelion passes of the Ulysses spacecraft

    Directory of Open Access Journals (Sweden)

    M. Lockwood

    2004-04-01

    Full Text Available Results from all phases of the orbits of the Ulysses spacecraft have shown that the magnitude of the radial component of the heliospheric field is approximately independent of heliographic latitude. This result allows the use of near-Earth observations to compute the total open flux of the Sun. For example, using satellite observations of the interplanetary magnetic field, the average open solar flux was shown to have risen by 29% between 1963 and 1987 and using the aa geomagnetic index it was found to have doubled during the 20th century. It is therefore important to assess fully the accuracy of the result and to check that it applies to all phases of the solar cycle. The first perihelion pass of the Ulysses spacecraft was close to sunspot minimum, and recent data from the second perihelion pass show that the result also holds at solar maximum. The high level of correlation between the open flux derived from the various methods strongly supports the Ulysses discovery that the radial field component is independent of latitude. We show here that the errors introduced into open solar flux estimates by assuming that the heliospheric field's radial component is independent of latitude are similar for the two passes and are of order 25% for daily values, falling to 5% for averaging timescales of 27 days or greater. We compare here the results of four methods for estimating the open solar flux with results from the first and second perehelion passes by Ulysses. We find that the errors are lowest (1–5% for averages over the entire perehelion passes lasting near 320 days, for near-Earth methods, based on either interplanetary magnetic field observations or the aa geomagnetic activity index. The corresponding errors for the Solanki et al. (2000 model are of the order of 9–15% and for the PFSS method, based on solar magnetograms, are of the order of 13–47%. The model of Solanki et al. is based on the continuity equation of open flux, and uses the

  18. Interdisciplinarity of Nano Research Fields : A Keyword Mining Approach

    NARCIS (Netherlands)

    Wang, L.; Notten, A.; Surpatean, A.

    2012-01-01

    Using a keyword mining approach, this paper explores the interdisciplinary and integrative dynamics in five nano research fields. We argue that the general trend of integration in nano research fields is converging in the long run, although the degree of this convergence depends greatly on the

  19. Field determination of multipollutant, open area combustion source emission factors with a hexacopter unmanned aerial vehicle

    Science.gov (United States)

    An emission sensor/sampler system was coupled to a NASA hexacopter unmanned aerial system (UAS) to characterize gases and particles in the plume emitted from open burning of military ordnance. The UAS/sampler was tested at two field sites resulting in 33 flights at Radford, VA a...

  20. Researching on Hawking Effect in a Kerr Space Time via Open Quantum System Approach

    International Nuclear Information System (INIS)

    Liu, Wen-Biao; Liu, Xian-Ming

    2014-01-01

    It has been proposed that Hawking radiation from a Schwarzschild or a de Sitter spacetime can be understood as the manifestation of thermalization phenomena in the framework of an open quantum system. Through examining the time evolution of a detector interacting with vacuum massless scalar fields, it is found that the detector would spontaneously excite with a probability the same as the thermal radiation at Hawking temperature. Following the proposals, the Hawking effect in a Kerr space time is investigated in the framework of an open quantum systems. It is shown that Hawking effect of the Kerr space time can also be understood as the the manifestation of thermalization phenomena via open quantum system approach. Furthermore, it is found that near horizon local conformal symmetry plays the key role in the quantum effect of the Kerr space time