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Sample records for omar parve tnis

  1. Malchiki malchiki! / Ahto Sooaru ; kommenteerinud Antti Parve

    Index Scriptorium Estoniae

    Sooaru, Ahto

    2009-01-01

    Antti Parve fotonäitusest "Malchiki malchiki". Fotosid sõdurpoistest on eksponeeritud erineval viisil Tapa väljaõppekeskuse õppehoones, Tallinna Loomaaias, Ambulartooriumi galeriis Kasepääl ja Vanemuise kontserdimaja fuajees. Fotograaf meenutab ajateenistust Eesti Kaitseväes

  2. Human parvovirus PARV4 in plasma pools of Chinese origin.

    Science.gov (United States)

    Ma, Y-Y; Guo, Y; Zhao, X; Wang, Z; Lv, M-M; Yan, Q-P; Zhang, J-G

    2012-10-01

    Human parvovirus 4 (PARV4) is present in blood and blood products. As the presence and levels of PARV4 in Chinese source plasma pools have never been determined, we implemented real-time quantitative PCR to investigate the presence of PARV4 in source plasma pools in China. Results showed that 26·15% (51/195) of lots tested positive for PARV4. The amounts of DNA ranged from 2·83 × 10(3) copies/ml to 2·35×10(7) copies/ml plasma. The high level of PARV4 in plasma pools may pose a potential risk to recipients. Further studies on the pathogenesis of PARV4 are urgently required. © 2012 The Author(s). Vox Sanguinis © 2012 International Society of Blood Transfusion.

  3. Where's Omar? Where Is Justice?

    Directory of Open Access Journals (Sweden)

    Tara Atluri

    2011-03-01

    Full Text Available Omar Khadr was arrested at the age of 15 by the U.S military and has remained in custody in Guantanamo for 8 years. Today, he plead guilty to five war crime charges. Despite stating in open court last summer that he would not plead guilty, today he muttered a confession. In accordance with the plea bargain, Khadr plead guilty to murder, attempted murder, conspiracy, providing material support to terrorists, and spying. Following this, a jury imposed the harshest possible sentence, 40 years imprisonment. Khadr may receive parole after eight years. The first year of this sentence will be served in Gauntanamo, following which he may be repatriated. The government of Canada does not have to repatriate Khadr, nor is parole guaranteed. Rather than hypothesizing outcomes, I want to discuss the case philosophically.

  4. Analysis of two human parvovirus PARV4 genotypes identified in human plasma for fractionation

    NARCIS (Netherlands)

    Fryer, Jacqueline F.; Delwart, Eric; Bernardin, Flavien; Tuke, Philip W.; Lukashov, Vladimir V.; Baylis, Sally A.

    2007-01-01

    The presence of the novel parvovirus PARV4 and a related variant, PARV5, was recently demonstrated in pooled plasma used in the manufacture of blood and plasma-derived medicinal products. DNA sequence analysis of nearly full-length genomes of four PARV4 and two PARV5 strains from manufacturing

  5. Omar Rincón: Sin tapujos

    Directory of Open Access Journals (Sweden)

    César Ulloa Tapia

    2009-03-01

    Full Text Available En la entrevista a Omar Rincón, catedrático colombiano, éste cuestiona el papel de los medios, las escuelas y facultades de periodismo, el Internet, los celulares. Afirma que la Academia necesita reinventarse. Las carreras de comunicación y periodismo han fracasado en la producción de narradores mediáticos, cuando no en la formación de críticos de la realidad. La comunicación más que un lugar de comunidad, es un lugar de conexión.

  6. Open Source Web Based Geospatial Processing with OMAR

    Directory of Open Access Journals (Sweden)

    Mark Lucas

    2009-01-01

    Full Text Available The availability of geospatial data sets is exploding. New satellites, aerial platforms, video feeds, global positioning system tagged digital photos, and traditional GIS information are dramatically increasing across the globe. These raw materials need to be dynamically processed, combined and correlated to generate value added information products to answer a wide range of questions. This article provides an overview of OMAR web based geospatial processing. OMAR is part of the Open Source Software Image Map project under the Open Source Geospatial Foundation. The primary contributors of OSSIM make their livings by providing professional services to US Government agencies and programs. OMAR provides one example that open source software solutions are increasingly being deployed in US government agencies. We will also summarize the capabilities of OMAR and its plans for near term development.

  7. Absence of novel human parvovirus (PARV4) in Danish mothers and children.

    Science.gov (United States)

    von Linstow, Marie-Louise; Rosenfeldt, Vibeke; Lindberg, Ellinor; Jensen, Lise; Hedman, Lea; Li, Xuemeng; Väisänen, Elina; Hedman, Klaus; Norja, Päivi

    2015-04-01

    The recently discovered human parvovirus 4 (PARV4) is found most frequently in injection drug users, HIV-positive patients, and in haemophiliacs. Studies from Ghana report the finding of PARV4 in plasma from 2 to 12% of children without acute infection, and in nasal secretions and faecal samples. Studies of PARV4 in children from industrialized countries are few. We aimed to describe the occurrence of PARV4 in a population-based birth cohort of 228 Danish mothers and their healthy children who previously participated in a study of respiratory tract infections in infancy. Children were included over a whole calendar year and were monitored through monthly home visits through the first year of life. Plasma samples for the present study were available from 228 mothers, 176 newborns, and 202 12-months-old children. All samples were analysed for the presence of PARV4 antibodies by enzyme immunoassay, and samples with detectable antibodies were in addition studied by real-time PCR. One (0.4%) of 228 mothers had PARV4 IgG exceeding the cut-off absorbance level and another had borderline IgG reactivity. No mother among these two had an acute infection, as they were IgM and PARV4 DNA negative. All blood samples from newborns and one-year-old children had IgG and IgM reactivity below cut-off. PARV4 is rare in Danish mothers and infants. Further studies are needed, in both rural and urban settings, to investigate the epidemiology and clinical significance of this novel human parvovirus. Copyright © 2015 Elsevier B.V. All rights reserved.

  8. Semblanza y liderazgo de Omar Dengo: vigencia de su pensamiento

    Directory of Open Access Journals (Sweden)

    Magdalena Alfaro-Rodríguez

    2009-06-01

    Full Text Available Recibido 29 de noviembre de 2007 • Aprobado 17 de junio de 2008 • Corregido 5 de mayo de 2009   Aspectos de la vida de Omar Dengo delinean su obra y lo definen como figura de connotado liderazgo humanista. Su quehacer docente y compromiso social se reflejan en su acción civilista que trasciende su época y aún hoy es vigente.

  9. Human parvovirus PARV4 DNA in tissues from adult individuals: a comparison with human parvovirus B19 (B19V

    Directory of Open Access Journals (Sweden)

    Rotellini Matteo

    2010-10-01

    Full Text Available Abstract Background PARV4 is a new member of the Parvoviridae family not closely related to any of the known human parvoviruses. Viremia seems to be a hallmark of PARV4 infection and viral DNA persistence has been demonstrated in a few tissues. Till now, PARV4 has not been associated with any disease and its prevalence in human population has not been clearly established. This study was aimed to assess the tissue distribution and the ability to persist of PARV4 in comparison to parvovirus B19 (B19V. Results PARV4 and B19V DNA detection was carried out in various tissues of individuals without suspect of acute viral infection, by a real time PCR and a nested PCR, targeting the ORF2 and the ORF1 respectively. Low amount of PARV4 DNA was found frequently (>40% in heart and liver of adults individuals, less frequently in lungs and kidneys (23,5 and 18% respectively and was rare in bone marrow, skin and synovium samples (5,5%, 4% and 5%, respectively. By comparison, B19V DNA sequences were present in the same tissues with a higher frequency (significantly higher in myocardium, skin and bone marrow except than in liver where the frequency was the same of PARV4 DNA and in plasma samples where B19V frequency was significantly lower than that of PARV4 Conclusions The particular tropism of PARV4 for liver and heart, here emerged, suggests to focus further studies on these tissues as possible target for viral replication and on the possible role of PARV4 infection in liver and heart diseases. Neither bone marrow nor kidney seem to be a common target of viral replication.

  10. Tegijad meenutavad "52 üllatust ja ideed" / Annika Maior, Ats Parve, Epp Kubu ...[jt.

    Index Scriptorium Estoniae

    2011-01-01

    Kultuuripealinna ootussarjas osalenud räägivad, kuidas idee teostamine kulges. Projektidest "Fantaasiaaed" (Annika Maior), "Camera obscura" (Ats Parve), "Tallinna bussijaam heliseb" (Epp, Kubu, Tõnis Hiiesalu), "Tänavamiimid" (Mihkel Ernits, Kaarel Väli), "Kunstijärjekord" (Flo Kasearu, Aet Ader, Grete Soosalu, Andra Aaloe)

  11. Omar Khadr, Hannah Arendt, and the Racialization of Rights’ Discourse

    Directory of Open Access Journals (Sweden)

    Valentina Capurri

    2016-08-01

    Full Text Available In this paper, I focus on the story of Omar Khadr, a Canadian minor who was held captive in Guantanamo Bay for a decade, to demonstrate that, at times, neither citizenship nor human rights offer any protection to those who, like Khadr, are citizens of a country and are certainly human beings, yet have been deprived of the rights associated with those statuses. By drawing on Hannah Arendt’s argument in The Origins of Totalitarianism, as well as some of her subsequent work, I critically assess the debate regarding whether the rights conferred upon citizens are the only true barriers against abuse, or whether human rights have become a more effective protection. I suggest that this debate is sterile as it fails to recognize that the issue is not which set of rights offers a better guarantee of protection, but how the discourse around citizenship and human rights remains racialized, to the point where certain individuals are considered neither citizens nor humans, and therefore are potentially subject to abuse. Focusing on Canada’s treatment of Khadr, I argue that racialization is the root cause of his denial of rights. My analysis aims to contribute to existing literature by refocusing the “rights debate” to demonstrate that any discussion around abstract rights fails to address the experiences of those racialized subjects whose rights have been denied.

  12. Mis põhjustab/soodustab vägivalda koolis? / Valter Parve, Mikko Lagerspetz, Erki Korp, Enn Toom, Kristiine Vahtramäe

    Index Scriptorium Estoniae

    2008-01-01

    Küsimusele vastavad TÜ Pärnu Kolledži lektor Valter Parve, TLÜ sotsioloogiaprofessor Mikko Lagerspetz, Tallinna laste turvakeskuse juhataja Erki Korp, usaldustelefoni projektijuht Enn Toom ja lastevanemate liidu koolitusjuht Kristiine Vahtramäe

  13. Reduction of dental metallic artefacts in CT: Value of a newly developed algorithm for metal artefact reduction (O-MAR)

    International Nuclear Information System (INIS)

    Kidoh, M.; Nakaura, T.; Nakamura, S.; Tokuyasu, S.; Osakabe, H.; Harada, K.; Yamashita, Y.

    2014-01-01

    Aim: To evaluate the image quality of O-MAR (Metal Artifact Reduction for Orthopedic Implants) for dental metal artefact reduction. Materials and methods: This prospective study received institutional review board approval and written informed consent was obtained. Thirty patients who had dental implants or dental fillings were included in this study. Computed tomography (CT) images were obtained through the oral cavity and neck during the portal venous phase. The system reconstructed the O-MAR-processed images in addition to the uncorrected images. CT attenuation and image noise of the soft tissue of the oral cavity were compared between the O-MAR and the uncorrected images. Qualitative analysis was undertaken between the two image groups. Results: The image noise of the O-MAR images was significantly lower than that of the uncorrected images (p < 0.01). O-MAR offered plausible attenuations of soft tissue compared with non-O-MAR. Better qualitative scores were obtained in the streaking artefacts and the degree of depiction of the oral cavity with O-MAR compared with non-O-MAR. Conclusion: O-MAR enables the depiction of structures in areas in which this was not previously possible due to dental metallic artefacts in qualitative image analysis. O-MAR images may have a supplementary role in addition to uncorrected images in oral diagnosis

  14. Air quality compliance improvements through operational management of air resources (OMAR)

    International Nuclear Information System (INIS)

    Goddard, W.B.; Goddard, C.B.

    1990-01-01

    Geothermal well fields and power plants require operational and emergency atmospheric venting. Venting activities are monitored for compliance with regulations which limit air pollutant emissions and Ambient Air Quality Standards (AAQS). Continuous compliance monitoring data which includes hydrogen sulfide (H2S) levels and meteorological conditions is only available moths after being compiled. In this paper an automated computerized system called OMAR is described in the following which checks data and allows users access to real-time and near real-time data reports. The data can then be used for managing necessary venting or other real-time data needs. The OMAR system hardware and software is descried and is in use at The Geysers and at the Coso KGRA geothermal developments in California. The system has been designed to assist developers, engineers, scientists, and the local air districts in their goal of maintaining ambient air quality within Federal, State and Local standards

  15. Phase I/IIa study of intratumoral/intracerebral or intravenous/intracerebral administration of Parvovirus H-1 (ParvOryx) in patients with progressive primary or recurrent glioblastoma multiforme: ParvOryx01 protocol

    International Nuclear Information System (INIS)

    Geletneky, Karsten; Hajda, Jacek; Huesing, Johannes; Rommelaere, Jean; Schlehofer, Joerg R; Leuchs, Barbara; Dahm, Michael; Krebs, Ottheinz; Knebel Doeberitz, Magnus von; Huber, Bernard

    2012-01-01

    The treatment of patients with malignant brain tumors remains a major oncological problem. The median survival of patients with glioblastoma multiforme (GBM), the most malignant type, is only 15 months after initial diagnosis and even less after tumor recurrence. Improvements of standard treatment including surgery and radio-chemotherapy have not lead to major improvements. Therefore, alternative therapeutics such as oncolytic viruses that specifically target and destroy cancer cells are under investigation. Preclinical data of oncolytic parvovirus H-1 (H-1PV) infection of glioma cells demonstrated strong cytotoxic and oncosuppressing effects, leading to a phase I/IIa trial of H-1PV in patients with recurrent GBM (ParvOryx01). ParvOryx01 is the first trial with a replication competent oncolytic virus in Germany. ParvOryx01 is an open, non-controlled, two groups, intra-group dose escalation, single center, phase I/IIa trial. 18 patients with recurrent GBM will be treated in 2 groups of 9 patients each. Treatment group 1 will first receive H-1PV by intratumoral injection and second by administration into the walls of the tumor cavity during tumor resection. In treatment group 2 the virus will initially be injected intravenously and afterwards, identical to group 1, into the surrounding brain tissue during tumor removal. Main eligibility criteria are: age of 18 years, unifocal recurrent GBM, amenable to complete or subtotal resection. Dose escalation will be based on the Continual Reassessment Method. The primary objective of the trial is local and systemic safety and tolerability and to determine the maximum tolerated dose (MTD). Secondary objectives are proof of concept (PoC) and Progression-free Survival (PFS) up to 6 months. This is the first trial with H-1PV in patients with recurrent GBM. The risks for the participants appear well predictable and justified. Furthermore, ParvOryx01 will be the first assessment of combined intratumoral and intravenous application

  16. Age as an Affective Factor in Influencing Public Speaking Anxiety of English Language Learners at Omar Al-Mukhtar University

    Science.gov (United States)

    Gaibani, Ahmed; Elmenfi, Fadil

    2016-01-01

    The study is to show how age factor can influence public speaking anxiety among English Language Learners at Omar Al-Mukhtar University. To indicate the influence of age factor a questionnaire was distributed to the participants of the study. As well as correlation was also undertaken to the data collected to investigate the influence of age…

  17. Technical and structural reading on ode Alraieah of Omar ibn Abi Rabieah and its emotional characteristic

    Directory of Open Access Journals (Sweden)

    2015-09-01

    Full Text Available Abstract: This article examines the famous Rbheah ode of Omar ibn Abi With The aim of finding The Structural form and some nice features. Knowing that this ods is the most famous and longest ode of Omar and there is in it the most characteristic of his poetry in the storied format which includes elements of the short story with its modern sense and depicts a happy life of The Umayyad period particularly those aspects that relate to women. And from this perspective has become the registered office of the poet's life and Reflection for his inner emotions. The formation of discussion like the following: Discussion Started With the introduction of what it should be noted Based on the announce new version.Then Addressed in this fifth issues and termination: 1.the main Thoughts and ideas in the Ode and its position and the way in which the poet has written ode.2.The Storied Level and dialog in theOde.3.The music in the ode and role of its weighs.4.The imaging level of the Ode in reflection for the Hejaz life. 5. Structural level of the Ode and its emotional aspects. in the end, The Paper achieved some conclusions, such as: the most remarkable is that Ibn Rbia is Sensory and womanish school leader that could link the Old dialogue Soul to Our contemporary world with poeticlyrics and dialogue Fiction.He is first real poet that granted to lyric poem the numerous technical features such as storytelling and dialogue and simplifying weights to singing.and this ode became famous for High precision in the selection of words.

  18. SU-E-I-75: Evaluation of An Orthopedic Metal Artifact Reduction (O-MAR) Algorithm On Patients with Spinal Prostheses Near Spinal Tumors

    International Nuclear Information System (INIS)

    Shen, Z; Xia, P; Djemil, T; Klahr, P

    2014-01-01

    Purpose: To evaluate the impact of a commercial orthopedic metal artifact reduction (O-MAR) algorithm on CT image quality and dose calculation for patients with spinal prostheses near spinal tumors. Methods: A CT electron density phantom was scanned twice: with tissue-simulating inserts only, and with a titanium insert replacing solid water. A patient plan was mapped to the phantom images in two ways: with the titanium inside or outside of the spinal tumor. Pinnacle and Eclipse were used to evaluate the dosimetric effects of O-MAR on 12-bit and 16-bit CT data, respectively. CT images from five patients with spinal prostheses were reconstructed with and without O-MAR. Two observers assessed the image quality improvement from O-MAR. Both pencil beam and Monte Carlo dose calculation in iPlan were used for the patient study. The percentage differences between non-OMAR and O-MAR datasets were calculated for PTV-min, PTV-max, PTV-mean, PTV-V100, PTV-D90, OAR-V10Gy, OAR-max, and OAR-D0.1cc. Results: O-MAR improved image quality but did not significantly affect the dose distributions and DVHs for both 12-bit and 16- bit CT phantom data. All five patient cases demonstrated some degree of image quality improvement from O-MAR, ranging from small to large metal artifact reduction. For pencil beam, the largest discrepancy was observed for OARV-10Gy at 5.4%, while the other seven parameters were ≤0.6%. For Monte Carlo, the differences between non-O-MAR and O-MAR datasets were ≤3.0%. Conclusion: Both phantom and patient studies indicated that O-MAR can substantially reduce metal artifacts on CT images, allowing better visualization of the anatomical structures and metal objects. The dosimetric impact of O-MAR was insignificant regardless of the metal location, image bit-depth, and dose calculation algorithm. O-MAR corrected images are recommended for radiation treatment planning on patients with spinal prostheses because of the improved image quality and no need to modify

  19. State secret privilege versus human rights: lessons from the European Court of Human Rights ruling on the Abu Omar case / Arianna Vedaschi

    Index Scriptorium Estoniae

    Vedaschi, Arianna

    2017-01-01

    Riigisaladuse ülimuslikkusest julgeoleku eesmärgil ning inimõiguste ja põhivabaduste kaitse konventsiooni artikli 3 tõlgendamisest Euroopa Inimõiguste Kohtu Abu Omar lahendi (23.veebr 2016) põhjal

  20. SU-E-I-63: Quantitative Evaluation of the Effects of Orthopedic Metal Artifact Reduction (OMAR) Software On CT Images for Radiotherapy Simulation

    Energy Technology Data Exchange (ETDEWEB)

    Jani, S [Sharp Memorial Hospital, San Diego, CA (United States)

    2014-06-01

    Purpose: CT simulation for patients with metal implants can often be challenging due to artifacts that obscure tumor/target delineation and normal organ definition. Our objective was to evaluate the effectiveness of Orthopedic Metal Artifact Reduction (OMAR), a commercially available software, in reducing metal-induced artifacts and its effect on computed dose during treatment planning. Methods: CT images of water surrounding metallic cylindrical rods made of aluminum, copper and iron were studied in terms of Hounsfield Units (HU) spread. Metal-induced artifacts were characterized in terms of HU/Volume Histogram (HVH) using the Pinnacle treatment planning system. Effects of OMAR on enhancing our ability to delineate organs on CT and subsequent dose computation were examined in nine (9) patients with hip implants and two (2) patients with breast tissue expanders. Results: Our study characterized water at 1000 HU with a standard deviation (SD) of about 20 HU. The HVHs allowed us to evaluate how the presence of metal changed the HU spread. For example, introducing a 2.54 cm diameter copper rod in water increased the SD in HU of the surrounding water from 20 to 209, representing an increase in artifacts. Subsequent use of OMAR brought the SD down to 78. Aluminum produced least artifacts whereas Iron showed largest amount of artifacts. In general, an increase in kVp and mA during CT scanning showed better effectiveness of OMAR in reducing artifacts. Our dose analysis showed that some isodose contours shifted by several mm with OMAR but infrequently and were nonsignificant in planning process. Computed volumes of various dose levels showed <2% change. Conclusions: In our experience, OMAR software greatly reduced the metal-induced CT artifacts for the majority of patients with implants, thereby improving our ability to delineate tumor and surrounding organs. OMAR had a clinically negligible effect on computed dose within tissues. Partially funded by unrestricted

  1. The Role of Social Evaluation in Influencing Public Speaking Anxiety of English Foreign Language Learners at Omar Al-Mukhtar University

    Science.gov (United States)

    Elmenfi, Fadil; Gaibani, Ahmed

    2016-01-01

    This study investigates the effect of social evaluation on Public Speaking Anxiety of English foreign language learners at Omar Al-Mukhtar University in Libya. A random sample of 111 students was used in the study. To analyse the collected data, means, standard deviations, a three-way ANOVA analysis, and the correlation coefficients were used with…

  2. Mapping CB1 cannabinoid receptors with [3H]OMAR in the Flinders rodent model of depression

    DEFF Research Database (Denmark)

    Nahimi, A.; Gjedde, A.; Wong, D. F.

    2012-01-01

    not significantly different. Conclusions: Although changes in CB1 receptor expression have been demonstrated in human suicide victims with depression and in animal models of depression, the present maps of [3H]OMAR binding revealed no difference between FSL and FRL rats. We used a single concentration of [3H......Background: The endocannabinoid system regulates cognitive and emotional processes and pathology of this system is implicated in psychiatric disorders, including depression and schizophrenia. The precise role of the endocannabinoid system in psychiatric disorders remains unclear, but changes...... in expression of CB1 receptors and subsequent altered modulation of monoamines is suggested in depression (Esteban & Garcia-Sevilla, 2011). CB1 receptor agonists, such as WIN55,212-2 and CP55,940 regulate synthesis and release of monoamines and are suggested as a novel therapy in the treatment of depression...

  3. 257__Omar_Tatsewarki

    African Journals Online (AJOL)

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    IRRIGATED FLUVISOLS ALONG RIVER TATSEWARKI, KANO, NIGERIA ... concentrations of heavy metals in wastewater irrigated Fluvisols and in the ..... Effects of. Wastewater Discharge on Heavy Metals. Pollution in Fadama Soils in Kano ...

  4. Méditation sur les mystères de la création Paul Valéry et Omar al Khayyâm

    Directory of Open Access Journals (Sweden)

    Dr Mohammad Reza Mohseni

    2012-09-01

    Full Text Available La méditation sur la mort, l’ordre de l’existence ainsi que les mystères de la Genèse constitue l’objet principal des études philosophiques dont s’inspirent, de temps à autre, la poésie et la littérature. Cette recherche se fixe comme objectif de démontrer si l’attitude des poètes Paul Valéry et Omar al Khayyâm à l’encontre des notions telles que la mort et l’existence tire son origine de leur affres de la mort, ou bien elle prend ses sources dans leurs préoccupations philosophiques. Nous allons étudier les attributs narcissiques des poèmes de Valéry, en pleine contradiction avec des vers cosmopolites et regorgés de sagesse de Khayyâm.

  5. Evaluation of Three Evaporation Estimation Techniques In A Semi-Arid Region (Omar El Mukhtar Reservoir Sluge, Libya- As a case Study

    Directory of Open Access Journals (Sweden)

    Lubna s. Ben Taher

    2017-02-01

    Full Text Available In many semi-arid countries in the world like Libya, drinking water supply is dependent on reservoirs water storage. Since the evaporation rate is very high in semi-arid countries, estimates and forecasts of reservoir evaporation rate can be useful in the management of major water source. Many researchers have been investigating the suitability of estimates evaporation rates methods in many climatic settings, infrequently of which were in an arid setting. This paper presents the modeling results of evaporation from Omar El Mukhtar Reservoir, Libya. Three techniques namely (artificial neural networks (ANN, Multiple linear regression (MLR and response surface methods (RSM were developed, to assess the estimation of monthly evaporation records from 2001 to 2009; their relative performance were compared using the coefficient of determination(E, mean absolute percentage error (MAPE%, and 95% confidence interval. The key variables used to develop and validate the models were: monthly (precipitation Rf., average temperature Temp., relative humidity Rh., sunshine hours Sh., atmospheric pressure Pa. and wind speed Ws.. The encouraging results approved that the models with more inputs generally had better accuracies and the ANN model performed superior to the other models in predicting monthly Evp with high E=0.86 and low MAPE%= 13.9 and the predicted mean within the range of observed 95CI%. In summary, it is revealed in this study that the ANN and RSM models are appropriate for predicting Evp using climatic inputs in semi-arid climate.

  6. La Riḥla de Omar Patún: el viaje de peregrinación a la Meca de un musulmán de Ávila a finales del siglo XV (1491–1495 = Omar Patún’s Riḥla : The Journey of the Pilgrimage to Mecca of a Muslim from Ávila at the End of the Fifteenth Century (1491–1495

    Directory of Open Access Journals (Sweden)

    Xavier Casassas Canals

    2015-06-01

    Full Text Available En este artículo presentamos la Riḥla de Omar Patún, un relato de viaje y de peregrinación desde Ávila a la Meca realizado por un musulmán castellano a finales del siglo XV. Se trata de un manuscrito inédito hallado en Calanda y conservado en la Biblioteca de Las Cortes de Aragón. Publicamos una selección de textos mostrando las principales etapas del viaje, las circunstancias del mismo y la descripción de algunas de las principales ciudades que visitó Omar Patún. A partir de algunas noticias y referencias, directas e indirectas, a acontecimientos históricos determinamos la fecha exacta del viaje de Omar Patún (1491–1495 y establecemos la cronología de las diferentes etapas y escalas. Ponemos así en conocimiento un documento fundamental para todos aquellos interesados en el estudio de la comunidad musulmana de época mudéjar, que aporta datos novedosos que habrá de tener en cuenta a partir de ahora cuando se hable de la religiosidad de los mudéjares castellanos y de los desplazamientos de éstos a Oriente y en especial a la Meca.This article presents Omar Patún’s Riḥla, an itinerary of the pilgrimage from Ávila to Mecca undertaken by a Castilian Muslim at the end of the fifteenth century. This is an unpublished manuscript found in Calanda and preserved in the Library of the Cortes de Aragón. The selection of texts offered here will identify the most important stages of the journey, its circumstances and the description of some of the cities visited by Patún. Certain news and references in the text to historical events, both direct and indirect, help to date Omar Patún’s journey between 1491–1495, and to establish the chronology of the different stages of the trip and stops on the way. We bring to light an outstanding source for those interested in the Islamic community in Mudejar times as it provides new insights into the religiosity of Castilian Mudejars and their journeys to the Middle

  7. 111- 116_Omar and Muhammedc

    African Journals Online (AJOL)

    User

    400 mm per year, but can grow in areas with as little as. 100 mm, and a dry period of 8 to 11 months (Joker,. 2000). It is commonly used in agroforestry systems ... systems e.g. alley cropping, restoration of soil fertility ... small pockets in forest or game reserves and in non- ... (CEC) obtained by 1M NH4OAc (pH 7.0) method as.

  8. Positron Emission Tomographic Imaging of the Cannabinoid Type 1 Receptor System with [11C]OMAR ([11C]JHU75528: Improvements in Image Quantification Using Wild-Type and Knockout Mice

    Directory of Open Access Journals (Sweden)

    Raúl Herance

    2011-11-01

    Full Text Available In this study, we assessed the feasibility of using positron emission tomography (PET and the tracer [11C]OMAR ([11C]JHU75528, an analogue of rimonabant, to study the brain cannabinoid type 1 (CB1 receptor system. Wild-type (WT andCB1 knockout (KO animals were imaged at baseline and after pretreatment with blocking doses of rimonabant. Brain uptake in WT animals was higher (50% than in KO animals in baseline conditions. After pretreatment with rimonabant, WT uptake lowered to the level of KO animals. The results of this study support the feasibility of using PET with the radiotracer [11C]JHU75528 to image the brain CB1 receptor system in mice. In addition, this methodology can be used to assess the effect of new drugs in preclinical studies using genetically manipulated animals.

  9. Nädal Toompeal / Ralf R Parve

    Index Scriptorium Estoniae

    Parve, Ralf R., 1946-2008

    2002-01-01

    Järg 27. veebr., 6,27. märts, 3,17,24. aprill, 10,22,29. mai, 5,12,19,26. juuni, 18,25. september, 2,16,23,30. oktoober, 13,20,27. november lk. 5, 5,11,18. detsember lk. 5. Riigikogu istungite kajastus. Kesknädal 24. apr. vt. Ants Käärma kiri R.R. Parvele. Parlamendisaadik

  10. Aidsiennetus kui kõlblusprobleem / Valdar Parve

    Index Scriptorium Estoniae

    Parve, Valdar, 1948-

    2003-01-01

    Aafrika aidsisurmade statistika ekstrapoleerimine Eesti oludesse on väärtegu; neid andmeid paisutatakse arutluslikult, nii mujal maailmas kui ka Eestis - ametliku aidsiennetuse tähtsaimaks vormiks on seni hirmu eskaleerimine

  11. Performance of a tagged neutron inspection system (TNIS) based on portable sealed generators

    International Nuclear Information System (INIS)

    Nebbia, G.; Pesente, S.; Lunardon, M.; Viesti, G.; LeTourneur, P.; Heuveline, F.; Mangeard, M.; Tcheng, C.

    2004-01-01

    A portable sealed neutron generator has been modified to produce 14MeV tagged neutron beams with an embedded YAP:Ce scintillation detector. The system has been tested by detecting the coincident gamma-rays produced in the irradiation of a graphite sample by means of a standard NaI(Tl) scintillator. Time resolution of about δt=4-5ns (FWHM) has been measured. The sealed neutron tube has been operated up to 10 7 neutron/s. Possible applications in non-destructive assays and future developments of the Tagged Neutron Inspection System concept are discussed

  12. Mu süda on mägedes : [luuletused] / Robert Burns ; tlk. Ralf Parve, Ants Oras, Urmas Tõnisson, Kullo Vende, Mart Mäger, Georg Eduard Luiga, Friedrich Reinhold Kreutzwald, Karl August Hermann, Johannes Vau, Lydia Koidula, Ado Grenzstein

    Index Scriptorium Estoniae

    Burns, Robert, 1759-1796

    2006-01-01

    Sisu: Mu süda on mägedes ; Hing mägises Shotis ; Mu isa oli farmer ; Künnipoiss ; Noor neiu vanal mehel ; Vana Rob Morris ; Meg veskilt ; Veski-Meg ; Willie pruulis õlut ; John Odratera ; Hägisele ; Shotlased, nüüd seiske kindlad! ; Invernessi neid ; Kuradi tants aktsiisiametnikuga ; Macphersoni hüvastijätt / tlk. Ralf Parve ; Macphersoni hüvastijätt / / tlk. Ants Oras ; Nii ja naa ; Hiirele ; Eleegia Peg Nicholsoni surma puhul ; Vaga Willie palve ; Epitaaf vagale Willièle ; Värsid poeet Fergussoni portree alla ; Lõikuskuu laul ; On kaldal kõrkjad reas ; Mu arm on nagu ruske roos ; Mu arm... ; Oo, mu arm on verev, verev roos ; Esimene suudlus lahkudes ; Mõte karmist saatusest ; Oh näeksin tühja nõmme peal ; Kui näeksin ; "Kui üksi olles näeksid, neid..." ; Käies pikas rohus ; Värsiread ; Mind naine tihti taob ; Rõõmus lesk ; Willie Wastleì naine ; Mul on naine ; John Anderson / tlk. Urmas Tõnisson ; Jaan Anderson / tlk. Karl August Hermann ; Sügiselaul ; Kündja ja lill ; Kodu ; Ometi ; Kõige kiuste ; Kui õis, mis õitseb heinamaal ; Põlev armastus ; Hans ja Krõõt : [luuletused]. Epigramme: Raamatukoi ; Impromptu ; Puudus. Ammustele aegadele : [luuletus]. Autori kohta eluloolisi andmeid lk. 179

  13. 1624-IJBCS -Article-Serigne Omar sarr+

    African Journals Online (AJOL)

    hp

    volumetric flask and dissolved with distilled water. A volume of 2 mL of this solution was again transferred in 200 mL volumetric flask and completed to the mark with distilled water. An aliquot of this stock standard .... The ration of the two variances (Fcalc) is compared with F0,99. (Snedecor law) (Gonzalez et al., 2007). Since.

  14. 2578-IJBCS-Article-Serigne Omar Sarr

    African Journals Online (AJOL)

    hp

    Les pourcentages d'inhibition. (PI) expriment l'effet antioxydant mesuré. Une activité de piégeage des deux radicaux libres a été associée aux deux extraits et à l'ensemble des fractions. Pour les tests d'inhibition de l'absorbance du radical DPPH•, les PI ont varié de (22,20±0,03)% à (91,30±0,08)%. Avec le radical ABTS+•, ...

  15. 2011-IJBCS- Article-Serigne Omar Sarr

    African Journals Online (AJOL)

    hp

    piégeage des deux radicaux libres. Lors des tests d'inhibition de l'absorbance du radical DPPH•, les PI ont varié de (18,15±0,01)% pour la fraction hexanique (2,5 µg/mL) à (92,45±0,01)% pour la fraction d'acétate d'éthyle (100 µg/mL). Avec le radical ABTS+•, les PI ont varié de (52,76±0,05)% pour la fraction hexanique.

  16. 1624-IJBCS -Article-Serigne Omar sarr+

    African Journals Online (AJOL)

    hp

    method for estimation of quinine in pharmaceutical dosage forms ... both as a bulk drug and in tablet formulations was developed and validated using .... and were analysed the following day to test the short-term stability (Maleque et al., 2012).

  17. Indira Gandhi sattus KGB konksu otsa / ref. Ralf R. Parve

    Index Scriptorium Estoniae

    2005-01-01

    29. jaanuaril suri Londonis 1984. aastani Moskvas KGB arhiivis töötanud erumajor Vassili Mitrohhin, kes koostas koos Christopher Andrew'ga KGB arhiivist kaasa võetud dokumentide alusel raamatu "Mitrohhini arhiiv". Septembris ilmus raamatu II osa "KGB ja kogu maailm", mille tegevustik toimub Indias. Professor Andrew püüab raamatus tõestada India endiste peaministrite Indira ja Radjiv Gandhi täielikku sõltuvust KGB-st. Lisad: Indira Priyadarashani Gandhi; Radjiv Gandhi

  18. Respublikaanide ja sotside pettus Loksal / Ralf R. Parve

    Index Scriptorium Estoniae

    Parve, Ralf R., 1946-2008

    2006-01-01

    Loksa linnavolikogu koalitsioon ja Keskerakond pidasid eraldi istungeid. Ebaseaduslike vahenditega valiti libavolikogu poolt valijamees presidendivalimisteks, see osutus õigustühiseks ja nüüd tuleb volikogul valijamees uuesti valida

  19. Ajalooteaduses pole absoluutset tõde olemas / Ralf R. Parve

    Index Scriptorium Estoniae

    Parve, Ralf R., 1946-2008

    2007-01-01

    4. oktoobril Tallinna Ülikoolis toimunud ümarlauast "Alternatiivsetest ajalookäsitlustest", kus ajaloo uurimise üle arutlesid ajaloolane Mart Laar, TLÜ Eesti Humanitaarinstituudi kultuuriteooria lektor Marek Tamm, TLÜ Ajaloo Instituudi direktor Magnus Ilmjärv ja TLÜ poliitikateooria professor Rein Ruutsoo. Ümarlauda juhtis rektor Rein Raud

  20. Eesti seisab oma ajaloo eest / Ralf R Parve

    Index Scriptorium Estoniae

    Parve, Ralf R., 1946-2008

    2007-01-01

    Vabadussõjas langenud Tallinna õpetajate ja õpilaste mälestussambast (skulptor Fredi Sannamees, arhitekt Anton Soans, tähtede autor Günther Reindorff) avamisest 1927. aastal, hilisematest mahavõtmistest ja taastamistest (skulptorid A. Mölder ja V. Mets)

  1. Rusçuklu Zarîfî Ömer Baba ve Manzum-Mensur Tasavvuf Terimleri Lügatçesi: Istılahât-ı Meşâyıh Zarîfî Omar Baba From Ruscuk and His Glossary Of Verse-Prose Sufi Terminology: Istilahât-i Mashayikh

    Directory of Open Access Journals (Sweden)

    Turgut KOÇOĞLU

    2012-09-01

    Full Text Available There is not enough information about Zarîfî Omar Baba in the sources we have studied. According to the available sources Zarîfî Omar Baba, who was from Ruscuk village within the borders of Bulgaria today, participated in Sa’diyye Sect and he ascended to the position of sheikh in this sect. Zarîfî has two works which are mentioned in the biograhical antologies. These are Pend-name and Divan. Yet, in the catalogue searches we have done 7 more works, which are denoted to belong to him, have been identified. These works are: Tasavvuf-nâme, İsm-i A’zam, Kitâb-ı İ'tikâd, Hikâye-yi Kan Kalesi, Beyân-ı Ser-encâm, Kısasu’l-Enbiyâ and Istılahât-ı Mashayikh. As far as we could study, Zarîfî’s works have religion-sufism and moral contents. His work, Istılahât-ı Mashayikh, which has not been mentioned in the sources, is a kind of dictionary of sufism terms. In this work, which starts with 23 verses narrating some religion and sufism themes, 70 sufism terms are explained in all. It is possible to group these terms into two as names and positions. In this work, names and their characteristics are written in prose while positions are written in verse. Firstly in verse, the author explains the name which identifies the qualities and characterisitcs of human being in his own sufistic point. Then in prose, he explains the positions the one, who has the characteristics of this name, will get to. In this article Zarîfî’s life, his literary personality and works; language, style and contents of Istılahât-ı Mashayikh have been examined. Besides, some terms in this work have been compared to other sufism dictionaries in order to clarify that meanings ascribed to the same terms show difference according to sects, tariqah and perhaps according to time and place. Finally, the text of Istılahât-ı Mashayikh has been translated into contemporary letters in accordance with its two copies by critical edition method.

  2. Eestlane olla on uhke ja hää? / Ralf R. Parve

    Index Scriptorium Estoniae

    Parve, Ralf R., 1946-2008

    1995-01-01

    F. R.Kreutzwald, M. J. Eisen, L. Koidula, A. Reinvald, J. Bergmann, P. Krusten, F. Tuglas, J. Hurt, V. Adams, J. V. .Jannsen, K. Merilaas : katkendeid artiklitest, kõnedest, kirjadest ja luuletustest

  3. 16. november 1988 : Eestist algas Nõukogude impeeriumi lagunemine / Vaino Väljas ; interv. Ralf R. Parve

    Index Scriptorium Estoniae

    Väljas, Vaino, 1931-

    2005-01-01

    Vestlus endise Eesti Kommunistliku Partei Keskkomitee peasekretäri Vaino Väljasega Eesti suveräänsusdeklaratsiooni koostamisest ja vastuvõtmisest 1988. aastal. Sisaldab artiklit "Kaks meenutuskaadrit nendest päevadest"

  4. Ikka mõtlen neile, kes siit viidi... / Ralf R. Parve

    Index Scriptorium Estoniae

    Parve, Ralf R., 1946-2008

    2007-01-01

    1941. aasta juuniküüditamisest, esimesest küüditamise mälestuspäevast 1942. aastal. Küüditatutele püstitatud mälestusmärkidest Eestis. Sisaldab Eesti elanike Venemaale küüditamise kronoloogiat alates 1558. aastast: "Juuniküüditamine oli ahela üks lüli"

  5. GMRT HI Observations of the Eridanus Group of Galaxies A. Omar ...

    Indian Academy of Sciences (India)

    The Fornax cluster having the highest galaxy density has the lowest spiral fraction, ... The present GMRT HI observations offer several advantages over studies carried ..... with coarser velocity resolutions for a model galaxy, and determined the ...

  6. Pintores de hoy: La geometría de Omar Rayo

    Directory of Open Access Journals (Sweden)

    Mario Rivero

    1968-05-01

    Full Text Available Se comienza hoy a sentir una inesperada afinidad con ese temperamento que propone la abstracción geométrica, cerebral, como medida plástica para nuestra época. Esta sería pues la manera de pintar, afín con el espíritu industrial, que quiere conocer la razón de las cosas y que indaga en ellas su expresión más exacta y desnuda. No se trata pues de intelectualizar; sino que esta expresión, no esotérica, pero sí recóndita, esta idea casi matemática de pureza, no puede expresarse en forma orgánica, y solo se hace efectiva en un idioma abstracto.

  7. La festa della circoncisione di Omar: luogo di incontri e di emozioni

    Directory of Open Access Journals (Sweden)

    Daniela Quaresmini

    2007-03-01

    Full Text Available The author, through an autobiographical account of the ceremony for the circumcision of her great-nephew, born of Italian mother and Tunisian father, held in Tunisi in August 2006, emphasizes the importance of supporting transcultural parenthood with the aim of guiding the mediation between different upbringing principles and enabling a more integrated growth of the new generations. That experience teaches that relationship dynamics within interracial families require an extra creative integration effort from their members who have different lifestyles and educational practices. At times psychological mediation is required to keep off both adults’ and children’s uncertainties and worries.

  8. 9/11-rünnakutest araabia kevadeni / Omar Ashour ; tõlkinud Villu Zirnask

    Index Scriptorium Estoniae

    Ashour, Omar

    2011-01-01

    Al-Qaida organisatsiooni muutumisest pärast 2001. a. 11. septembrit. Autori sõnul on luureoperatsioonide, mehitamata rünnakute,džihaadi ridades toimunud muutuste ja araabia kevade koosmõju nurjanud al-Qaida tsentraalse juhtimise, al-Qaidast lähtuv ülemaailmne oht on märkimisväärselt vähenenud

  9. Study of Occupational Safety and Health Audit on Facilities at Ungku Omar College, Universiti Kebangsaan Malaysia (UKM): A Preliminary Analysis

    Science.gov (United States)

    Ariffin, Kadir; Ahmad, Shaharuddin; Aiyub, Kadaruddin; Awang, Azhan; Aziz, Azmi; Mohamad, Lukman Z.; Mamat, Samsu Adabi

    2010-01-01

    Occupational safety and health (OSH) in Universiti Kebangsaan Malaysia (UKM) is being considered as an important program to measure employee and student welfare and well-being. During academic session, apart from attending lectures, laboratory works, tutorial and library search, majority of students spend most of their time in residential…

  10. The central biobank and virtual biobank of BiOMarKaPD: a resource for studies on neurodegenerative diseases

    NARCIS (Netherlands)

    Reijs, B.L.R.; Teunissen, C.E.; Goncharenko, N.; Betsou, F.; Blennow, K.; Baldeiras, I.; Brosseron, F.; Cavedo, E.; Fladby, T.; Froelich, L.; Gabryelewicz, T.; Gurvit, H.; Kapaki, E.; Koson, P.; Kulic, L.; Lehmann, S.; Lewczuk, P.; Lleo, A.; Maetzler, W.; de Mendonca, A.; Miller, A.M.; Molinuevo, J.L.; Mollenhauer, B.; Parnetti, L.; Rot, U.; Schneider, A.; Simonsen, A.H.; Tagliavini, F.; Tsolaki, M.; Verbeek, M.M.; Verhey, F. R. J.; Zboch, M.; Winblad, B.; Scheltens, P.; Zetterberg, H.; Visser, P.J.

    2015-01-01

    Biobanks are important resources for biomarker discovery and assay development. Biomarkers for Alzheimer's and Parkinson's disease (BIOMARKAPD) is a European multicenter study, funded by the EU Joint Programme-Neurodegenerative Disease Research, which aims to improve the clinical use of body fluid

  11. Rentismo y modelo liberalizador en Costa Rica. El caso de la fundación Omar Dengo: 1987-2009

    Directory of Open Access Journals (Sweden)

    Randall Blanco Lizano

    2011-07-01

    El fenómeno del rentismo se trataba de un fenómeno exclusivo del modelo de sustitución de importaciones o se trata de una modalidad de usufructo extensiva al modelo liberalizador?. Y si esa modalidad de aprovechamiento es extensiva al nuevo modelo: ¿quiénes son los nuevos rentistas en la Costa Rica de la libre competencia y qué mecanismos utilizan para producir sus rentas?.

  12. Die Analyse der Überlieferungen Bezüglich des Zusammentreffens von Khalifen Omar und Uwais al-Qarani

    Directory of Open Access Journals (Sweden)

    Enbiya Yıldırım

    2010-06-01

    Full Text Available Her dinde sembolik bir hüviyet kazanan insanlar vardır. Bu kişiler kendi alanlarında gösterdikleri başarılar veya öne çıkan meziyetleri nedeniyle örnek olarak ilk zikredilen kimselerdir. İslam ahlakı bağlamında anneye iyilik dendiğinde de akla ilk gelen isim Uveys elKarenî’dir. Uveys’in gerek yaşayıp yaşamadığı ve gerekse onunla ilgili anlatılanlar rivayetlerde son derece karmaşık ve çelişik bilgiler içermektedir. Biz bu makalemizde Muslim’in Sahîh’inde onun faziletlerinden bahseden üç rivayeti gerçeklik bağlamında tahlil ettik. Böylece Uveys konulu çalışmalara bir katkı sağlamış olduk.

  13. Placental transmission of human parvovirus 4 in newborns with hydrops, Taiwan.

    Science.gov (United States)

    Chen, Mao-Yuan; Yang, Shiu-Ju; Hung, Chien-Ching

    2011-10-01

    In studying the epidemiology of parvovirus 4 (PARV4) in Taiwan, we detected DNA in plasma of 3 mothers and their newborns with hydrops. In 1 additional case, only the mother had PARV4 DNA. Our findings demonstrate that PARV4 can be transmitted through the placenta.

  14. Detection of human parvovirus 4 viremia in the follow-up blood samples from seropositive individuals suggests the existence of persistent viral replication or reactivation of latent viral infection.

    Science.gov (United States)

    Chen, Mao-Yuan; Hung, Chien-Ching; Lee, Kuang-Lun

    2015-06-19

    The transmission routes for human parvovirus 4 (PARV4) infections in areas with high seroprevalence are not known. In the work described here, persistent PARV4 viral replication was investigated by conducting a longitudinal study. Ten healthcare workers each provided a blood sample at the beginning of the study (first sample) and 12 months later (second sample). The paired samples were tested for PARV4-positivity by immunoblotting analysis and nested polymerase chain reactions. IgG antibodies against PARV4 were detected in six participants, three of whom also had IgM antibodies against PARV4. The immunoblotting results did not vary over time. PARV4 DNA was detected in the first blood sample from one participant who had IgG antibodies against PARV4 and in the second blood samples from 2 participants who had IgG and IgM antibodies against PARV4. Detection of PARV4 DNA in the second blood samples from two seropositive participants suggests the existence of persistent PARV4 replication or reactivation of inactive virus in the tissues. The finding of persistent or intermittent PARV4 replication in individuals with past infections provides an important clue toward unraveling the non-parenteral transmission routes of PARV4 infection in areas where the virus is endemic.

  15. First record of the nematode Libyostrongylus dentatus Hoberg, Lloyd & Omar, 1995 (Trichostrongylidae) in ostriches (Struthio camelus Linnaeus, 1758) (Struthionidae) outside the Americas.

    Science.gov (United States)

    Andrade, Josiana Gomes de; Kumsa, Bersissa; Ayana, Dinka; Vieira, Ricardo Augusto Mendonça; Santos, Clóvis de Paula; Iñiguez, Alena Mayo; DaMatta, Renato Augusto

    2018-04-13

    Libyostrongylus douglassii, Libyostrongylus dentatus and Libyostrongylus magnus are nematodes that infect ostriches. The first species has been identified in ostriches from Africa, Europe, Americas and Oceania. Although the natural range of ostriches is Africa, L. dentatus was first described in birds from the USA and later identified in Brazil, where co-infections with L. douglassii have been commonly reported. Libyostrongylus magnus is known from the original description only. There are a few reports on infections with L. douglassii in ostriches from Africa and all farmed birds examined are from the southern region of the continent. The aim of this report was to verify Libyostrongylus spp. infections in wild ostriches from Ethiopia. Fecal samples from ostriches, Struthio molybdophanes, were collected and submitted to coproculture. Infective larvae were identified to the species level based on general morphology and morphometry. In addition, phylogenetic analysis of the first and second internal transcribed spacer (ITS1 and ITS2) of the nuclear ribosomal DNA was performed. Infective larvae from Ethiopian ostriches had the morphological characteristics of L. dentatus. Confidence interval estimate for sheath tail length from Ethiopian Libyostrongylus sp. isolates overlapped one for Brazilian L. dentatus. Neighbor-joining and Maximum Likelihood phylogenetic trees based on sequences of the ITS1 and ITS2 regions revealed that the Ethiopian samples belong to the L. dentatus species clade. Monospecific infections with L. dentatus were confirmed in Ethiopian wild ostriches, opposed to the co-infections typically found in the Americas. To our knowledge, this is the first record of L. dentatus from African ostriches, the region from which this parasite originated.

  16. Monsieur Omar Fassi Fihri Secrétaire perpétuel Académie HASSAN II des Sciences et Techniques Royaume du Maroc

    CERN Document Server

    Maximilien Brice

    2010-01-01

    CERN-HI-1007135 01: M. Gouighri, Boursier de l’Académie des Sciences, Université Hassan II; J. Collot, Directeur du Laboratoire international associé; R. Heuer,\tDirecteur général du CERN;O. Fassi Fehri, Secrétaire perpétuel, Académie Hassan II des Sciences et Techniques, Maroc; S. Boutouil, Boursière du Laboratoire international associé; R. Klapisch, Fondation Partager le Savoir, Président et fondateur; G.Carnot, Président de la Fondation Carnot.

  17. CTC Sentinel. Volume 3, Issue 1, January 2010. The Facade of Allegiance: Bin Ladin’s Dubious Pledge to Mullah Omar

    Science.gov (United States)

    2010-01-01

    Jackal: The Search for Car- los, the World’s Most Wanted Man (New York: Random House, 1993). 10 Gerard Chaliand and Arnaud Blin, Histoire du terror...Qissat al-bay’at al-‘arabiya li-amir al- mu’minin Mullah Muhammad ‘Umar, undated, posted on various jihadist web forums on July 19-20, 2007. Thanks to...groups. It is a web of overlapping conspiracies, often piggy-backing on local conflicts and grievances. In many ways it is a transnational secret

  18. Low Prevalence of Parvovirus 4 in HIV-infected Children in Denmark.

    Science.gov (United States)

    Rosenfeldt, Vibeke; Norja, Päivi; Lindberg, Ellinor; Jensen, Lise; Hedman, Lea; Väisänen, Elina; Li, Xuemeng; Hedman, Klaus; von Linstow, Marie-Louise

    2015-07-01

    Parvovirus 4 (PARV4) has been associated with HIV infection in adults. We examined plasma samples from 46 HIV-infected 0-year-old to 16-year-old children for the presence of PARV4. Four children (8.7%) had detectable PARV4 IgG and 1 had IgM. The result of PARV4 polymerase chain reaction was found to be negative in all patients. PARV4 seropositivity was associated with low CD4 count but not with HIV viral load.

  19. Testing UK blood donors for exposure to human parvovirus 4 using a time-resolved fluorescence immunoassay to screen sera and Western blot to confirm reactive samples.

    Science.gov (United States)

    Maple, Peter A C; Beard, Stuart; Parry, Ruth P; Brown, Kevin E

    2013-10-01

    Human parvovirus 4 (ParV4), a newly described member of the family Parvoviridae, like B19V, has been found in pooled plasma preparations. The extent, and significance, of ParV4 exposure in UK blood donors remain to be determined and reliable detection of ParV4 immunoglobulin (Ig)G, using validated methods, is needed. With ParV4 virus-like particles a ParV4 IgG time-resolved fluorescence immunoassay (TRFIA) was developed. There is no gold standard or reference assay for measuring ParV4 IgG and the utility of the TRFIA was first examined using a panel of sera from people who inject drugs (PWIDS)--a high-prevalence population for ParV4 infection. Western blotting was used to confirm the specificity of TRFIA-reactive sera. Two cohorts of UK blood donor sera comprising 452 sera collected in 1999 and 156 sera collected in 2009 were tested for ParV4 IgG. Additional testing for B19V IgG, hepatitis C virus antibodies (anti-HCV), and ParV4 DNA was also undertaken. The rate of ParV4 IgG seroprevalence in PWIDS was 20.7% and ParV4 IgG was positively associated with the presence of anti-HCV with 68.4% ParV4 IgG-positive sera testing anti-HCV-positive versus 17.1% ParV4 IgG-negative sera. Overall seropositivity for ParV4 IgG, in 608 UK blood donors was 4.76%. The ParV4 IgG seropositivity for sera collected in 1999 was 5.08%, compared to 3.84% for sera collected in 2009. No ParV4 IgG-positive blood donor sera had detectable ParV4 DNA. ParV4 IgG has been found in UK blood donors and this finding needs further investigation. © 2013 American Association of Blood Banks.

  20. Lahingutegevuse reeglite õiguslik tähendus ja nende rikkumisele järgnev vastutus : [teadusmagistritöö] / Silva Kirsimägi ; Tartu Ülikool, õigusteaduskond ; juhendajad: Rain Liivoja, Andres Parve

    Index Scriptorium Estoniae

    Kirsimägi, Silva

    2010-01-01

    Lahingutegevuse reeglite olemusest, enesekaitse mõistest, lahingutegevuse reeglite õiguslikust regulatsioonist rahvusvahelistel sõjalistel operatsioonidel, lahingutegevuse reeglite rikkumisega seotud õiguslikest küsimustest

  1. Human parvovirus 4 prevalence among HTLV-1/2 infected individuals in Brazil.

    Science.gov (United States)

    Slavov, Svetoslav Nanev; Otaguiri, Katia Kaori; Smid, Jerusa; de Oliveira, Augusto Cesar Penalva; Casseb, Jorge; Martinez, Edson Zangiacomi; Covas, Dimas Tadeu; Eis-Hübinger, Anna Maria; Kashima, Simone

    2017-04-01

    Human parvovirus 4 (PARV4), a Tetraparvovirus, has been largely found in HIV, HBV, or HCV infected individuals. However, there is no data for the PARV4 occurrence in Human T-lymphotropic virus (HTLV-1/2) infected individuals, despite similar transmission routes. Here, PARV4 viremia was evaluated in 130 HTLV infected patients under care of a Brazilian HTLV outpatient clinic. PARV4 viremia was detected in 6.2% of the HTLV-1 infected patients. Most PARV4 positives showed no evidence for parenterally transmitted infections. It is suggested that in Brazil, transmission routes of PARV4 are more complex than in Europe and North America and resemble those in Africa. J. Med. Virol. 89:748-752, 2017. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  2. Human Parvovirus 4 in Nasal and Fecal Specimens from Children, Ghana

    Science.gov (United States)

    Drexler, Jan Felix; Reber, Ulrike; Muth, Doreen; Herzog, Petra; Annan, Augustina; Ebach, Fabian; Sarpong, Nimarko; Acquah, Samuel; Adlkofer, Julia; Adu-Sarkodie, Yaw; Panning, Marcus; Tannich, Egbert; May, Jürgen; Drosten, Christian

    2012-01-01

    Nonparenteral transmission might contribute to human parvovirus 4 (PARV4) infections in sub-Saharan Africa. PARV4 DNA was detected in 8 (0.83%) of 961 nasal samples and 5 (0.53%) of 943 fecal samples from 1,904 children in Ghana. Virus concentrations ≤6–7 log10 copies/mL suggest respiratory or fecal–oral modes of PARV4 transmission. PMID:23018024

  3. Layer 5 Callosal Parvalbumin-Expressing Neurons: A Distinct Functional Group of GABAergic Neurons.

    Science.gov (United States)

    Zurita, Hector; Feyen, Paul L C; Apicella, Alfonso Junior

    2018-01-01

    Previous studies have shown that parvalbumin-expressing neurons (CC-Parv neurons) connect the two hemispheres of motor and sensory areas via the corpus callosum, and are a functional part of the cortical circuit. Here we test the hypothesis that layer 5 CC-Parv neurons possess anatomical and molecular mechanisms which dampen excitability and modulate the gating of interhemispheric inhibition. In order to investigate this hypothesis we use viral tracing to determine the anatomical and electrophysiological properties of layer 5 CC-Parv and parvalbumin-expressing (Parv) neurons of the mouse auditory cortex (AC). Here we show that layer 5 CC-Parv neurons had larger dendritic fields characterized by longer dendrites that branched farther from the soma, whereas layer 5 Parv neurons had smaller dendritic fields characterized by shorter dendrites that branched nearer to the soma. The layer 5 CC-Parv neurons are characterized by delayed action potential (AP) responses to threshold currents, lower firing rates, and lower instantaneous frequencies compared to the layer 5 Parv neurons. Kv1.1 containing K + channels are the main source of the AP repolarization of the layer 5 CC-Parv and have a major role in determining both the spike delayed response, firing rate and instantaneous frequency of these neurons.

  4. Case note: Supreme Court of Canada (Prime Minister and ors v Khadr (Omar Ahmed), Amnesty International (Canadian Section, English Branch) (intervening) and ors (intervening), Final appeal judgment, 2010 SCC 3)

    NARCIS (Netherlands)

    Clarke, L.

    2010-01-01

    Whether the principles of international law and comity that normally precluded application of the Constitution Act, 1982(‘Canadian Charter’) to Canadian officials acting abroad applied to the assistance they provided to US authorities at Guantánamo Bay. Whether the deprivation of the liberty and

  5. High prevalence of human parvovirus 4 infection in HBV and HCV infected individuals in shanghai.

    Science.gov (United States)

    Yu, Xuelian; Zhang, Jing; Hong, Liang; Wang, Jiayu; Yuan, Zhengan; Zhang, Xi; Ghildyal, Reena

    2012-01-01

    Human parvovirus 4 (PARV4) has been detected in blood and diverse tissues samples from HIV/AIDS patients who are injecting drug users. Although B19 virus, the best characterized human parvovirus, has been shown to co-infect patients with hepatitis B or hepatitis C virus (HBV, HCV) infection, the association of PARV4 with HBV or HCV infections is still unknown.The aim of this study was to characterise the association of viruses belonging to PARV4 genotype 1 and 2 with chronic HBV and HCV infection in Shanghai.Serum samples of healthy controls, HCV infected subjects and HBV infected subjects were retrieved from Shanghai Center for Disease Control and Prevention (SCDC) Sample Bank. Parvovirus-specific nested-PCR was performed and results confirmed by sequencing. Sequences were compared with reference sequences obtained from Genbank to derive phylogeny trees.The frequency of parvovirus molecular detection was 16-22%, 33% and 41% in healthy controls, HCV infected and HBV infected subjects respectively, with PARV4 being the only parvovirus detected. HCV infected and HBV infected subjects had a significantly higher PARV4 prevalence than the healthy population. No statistical difference was found in PARV4 prevalence between HBV or HCV infected subjects. PARV4 sequence divergence within study groups was similar in healthy subjects, HBV or HCV infected subjects.Our data clearly demonstrate that PARV4 infection is strongly associated with HCV and HBV infection in Shanghai but may not cause increased disease severity.

  6. First report of human parvovirus 4 detection in Iran.

    Science.gov (United States)

    Asiyabi, Sanaz; Nejati, Ahmad; Shoja, Zabihollah; Shahmahmoodi, Shohreh; Jalilvand, Somayeh; Farahmand, Mohammad; Gorzin, Ali-Akbar; Najafi, Alireza; Haji Mollahoseini, Mostafa; Marashi, Sayed Mahdi

    2016-08-01

    Parvovirus 4 (PARV4) is an emerging and intriguing virus that currently received many attentions. High prevalence of PARV4 infection in high-risk groups such as HIV infected patients highlights the potential clinical outcomes that this virus might have. Molecular techniques were used to determine both the presence and the genotype of circulating PARV4 on previously collected serum samples from 133 HIV infected patients and 120 healthy blood donors. Nested PCR was applied to assess the presence of PARV4 DNA genome in both groups. PARV4 DNA was detected in 35.3% of HIV infected patients compared to 16.6% healthy donors. To genetically characterize the PARV4 genotype in these groups, positive samples were randomly selected and subjected for sequencing and phylogenetic analysis. All PARV4 sequences were found to be genotype 1 and clustered with the reference sequences of PARV4 genotype 1. J. Med. Virol. 88:1314-1318, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  7. Occurrence of human bocaviruses and parvovirus 4 in solid tissues.

    Science.gov (United States)

    Norja, Päivi; Hedman, Lea; Kantola, Kalle; Kemppainen, Kaisa; Suvilehto, Jari; Pitkäranta, Anne; Aaltonen, Leena-Maija; Seppänen, Mikko; Hedman, Klaus; Söderlund-Venermo, Maria

    2012-08-01

    Human bocaviruses 1-4 (HBoV1-4) and parvovirus 4 (PARV4) are recently discovered human parvoviruses. HBoV1 is associated with respiratory infections of young children, while HBoV2-4 are enteric viruses. The clinical manifestations of PARV4 remain unknown. The objective of this study was to determine whether the DNAs of HBoV1-4 and PARV4 persist in human tissues long after primary infection. Biopsies of tonsillar tissue, skin, and synovia were examined for HBoV1-4 DNA and PARV4 DNA by PCR. Serum samples from the tissue donors were assayed for HBoV1 and PARV4 IgG and IgM antibodies. To obtain species-specific seroprevalences for HBoV1 and for HBoV2/3 combined, the sera were analyzed after virus-like particle (VLP) competition. While HBoV1 DNA was detected exclusively in the tonsillar tissues of 16/438 individuals (3.7%), all of them ≤8 years of age. HBoV2-4 and PARV4 DNAs were absent from all tissue types. HBoV1 IgG seroprevalence was 94.9%. No subject had HBoV1 or PARV4 IgM, nor did they have PARV4 IgG. The results indicate that HBoV1 DNA occurred in a small proportion of tonsils of young children after recent primary HBoV1 infection, but did not persist long in the other tissue types studied, unlike parvovirus B19 DNA. The results obtained by the PARV4 assays are in line with previous results on PARV4 epidemiology. Copyright © 2012 Wiley Periodicals, Inc.

  8. Studies on the inactivation of human parvovirus 4.

    Science.gov (United States)

    Baylis, Sally A; Tuke, Philip W; Miyagawa, Eiji; Blümel, Johannes

    2013-10-01

    Human parvovirus 4 (PARV4) is a novel parvovirus, which like parvovirus B19 (B19V) can be a contaminant of plasma pools used to prepare plasma-derived medicinal products. Inactivation studies of B19V have shown that it is more sensitive to virus inactivation strategies than animal parvoviruses. However, inactivation of PARV4 has not yet been specifically addressed. Treatment of parvoviruses by heat or low-pH conditions causes externalization of the virus genome. Using nuclease treatment combined with real-time polymerase chain reaction, the extent of virus DNA externalization was used as an indirect measure of the inactivation of PARV4, B19V, and minute virus of mice (MVM) by pasteurization of albumin and by low-pH treatment. Infectivity studies were performed in parallel for B19V and MVM. PARV4 showed greater resistance to pasteurization and low-pH treatment than B19V, although PARV4 was not as resistant as MVM. There was a 2- to 3-log reduction of encapsidated PARV4 DNA after pasteurization and low-pH treatment. In contrast, B19V was effectively inactivated while MVM was stable under these conditions. Divalent cations were found to have a stabilizing effect on PARV4 capsids. In the absence of divalent cations, even at neutral pH, there was a reduction of PARV4 titer, an effect not observed for B19V or MVM. In the case of heat treatment and incubation at low pH, PARV4 shows intermediate resistance when compared to B19V and MVM. Divalent cations seem important for stabilizing PARV4 virus particles. © 2013 American Association of Blood Banks.

  9. Development of the EURITRACK tagged neutron inspection system

    International Nuclear Information System (INIS)

    Perot, B.; Carasco, C.; Bernard, S.

    2007-01-01

    The EURopean Illicit TRAfficing Countermeasures Kit (EURITRACK) project is part of the 6th European Union Framework Program. It aims at developing a Tagged Neutron Inspection System (TNIS) to detect illicit materials, such as explosives and narcotics, in cargo containers. Fast neutron induced reactions produce specific gamma-rays used to determine the chemical composition of the inspected material. The associated particle technique is employed to precisely locate the interaction points of the neutrons. A new deuterium-tritium neutron generator has been developed, including a pixelized alpha particle detector. The TNIS also comprises high-efficiency fast neutron and gamma-ray detectors, a dedicated front-end electronics and an integrated software to entirely drive the system and automatically process the data. Most components have been integrated during last months at Institute Ruder Boskovic, in Zagreb, Croatia. An overview of the TNIS and of its preliminary performances is presented

  10. Linnavolikogu hambutus ja Riigikogu jäikus / Ela Tomson

    Index Scriptorium Estoniae

    Tomson, Ela, 1945-

    2005-01-01

    Vastuseks Valter Parve kirjutisele 17. nov. Pärnu Postimehes. Parlamendiliige kaitseb oma seisukohti seoses Pärnu volikogu istungiga, samuti põhjendab oma eemalejäämist kuuelapselisi peresid puudutava seaduseelnõu arutelult Riigikogus

  11. Tartu Keskkonnahariduse Keskuse Loodusmaja = Nature School of Tartu Environmental Education Centre

    Index Scriptorium Estoniae

    2015-01-01

    Tartu Keskkonnahariduse Keskuse Loodusmaja Lille tänav 10, valminud 2013. Arhitektuurivõistlus 2010. Arhitektid Martin Kinks, Risto Parve, Kai Süda, Margit Valma (Karisma Arhitktid), Diana Taalfeld (NU Arhitektuur). Sisearhitekt Tõnis Kalve

  12. Impedance spectroscopy of organic magnetoresistance devices—Effect of interface disorder

    International Nuclear Information System (INIS)

    Fayolle, M.; Yamaguchi, M.; Ohto, T.; Tada, H.

    2015-01-01

    Organic magnetoresistance (OMAR) can be caused by either single carrier (bipolaron) or double carriers (electron-hole)-based mechanisms. In order to consider applications for OMAR, it is important to control the mechanism present in the device. In this paper, we report the effect of traps on OMAR resulting of disorder at the interface between the organic active layer with the hole injection layer [poly(3,4-ethylenedioxythiophene): poly(styrenesulfonate): PEDOT:PSS]. It has been found that while the single carriers OMAR is enhanced by the presence of traps, the double carriers OMAR is totally removed in a sample with a high interface trap density. The reasons for these results are discussed based on the impedance spectroscopy measurements. First, the mechanism (single or double carriers) responsible of the OMAR was determined with the support of the capacitance measurement. Then, the influence of traps was discussed with the Nyquist diagrams and phase angle-frequency plots of the samples. The results suggested that with a rough interface and thus high disorder, the presence of traps enhanced the bipolaron formation. Traps also acted as recombination centers for electron-hole pairs, which prevented the double carriers OMAR in devices with a rough interface. On the other hand, with a low trap density, i.e., with a smooth surface, the single carrier OMAR decreased, and double carriers OMAR appeared. The sign of the OMAR could then be controlled by simply sweeping the bias voltage. This work demonstrated that the roughness at the interface is important for controlling OMAR and its reproducibility, and that the combination of OMAR measurement and impedance spectroscopy is helpful for clarifying the processes at the interface

  13. Sudaani presidenti süüdistatakse genotsiidis / Indrek Veiserik

    Index Scriptorium Estoniae

    Veiserik, Indrek

    2008-01-01

    14. juulil 2008 Haagis alanud Rahvusvahelise Kriminaalkohtu protsessil süüdistatakse Sudaani presidenti Omar Hassan al-Bashiri inimsusevastaste kuritegude toimepanekus Sudaani konfliktipiirkonnas Darfuris

  14. Electron Resonance Decay into a Biological Function: Decrease in Viability of E. coli Transformed by Plasmid DNA Irradiated with 0.5-18 eV Electrons.

    Science.gov (United States)

    Kouass Sahbani, S; Cloutier, P; Bass, A D; Hunting, D J; Sanche, L

    2015-10-01

    Transient negative ions (TNIs) are ubiquitous in electron-molecule scattering at low electron impact energies (0-20 eV) and are particularly effective in damaging large biomolecules. Because ionizing radiation generates mostly 0-20 eV electrons, TNIs are expected to play important roles in cell mutagenesis and death during radiotherapeutic cancer treatment, although this hypothesis has never been directly verified. Here, we measure the efficiency of transforming E. coli bacteria by inserting into the cells, pGEM-3ZfL(-) plasmid DNA that confers resistance to the antibiotic ampicillin. Before transformation, plasmids are irradiated with electrons of specific energies between 0.5 and 18 eV. The loss of transformation efficiency plotted as a function of irradiation energy reveals TNIs at 5.5 and 9.5 eV, corresponding to similar states observed in the yields of DNA double strand breaks. We show that TNIs are detectable in the electron-energy dependence of a biological process and can decrease cell viability.

  15. Basin F Overburden and Soil Sampling and Analysis Study, Rocky Mountain Arsenal

    Science.gov (United States)

    1982-05-01

    and the material lodged in the shoe of the sampler z•s pressed out and placed in the bottom of the sleeve. In tnis tray, an undisturbed sample of the...b):______ A. Szandard dev--aciol of lowiest stanidard (S): _____ jmmzltnof lzw.sz standard (c): _______ i~veraq* &ýs-: banca cý lovesc standard

  16. Separating positive and negative magnetoresistance in organic semiconductor devices

    NARCIS (Netherlands)

    Bloom, F.L.; Wagemans, W.; Kemerink, M.; Koopmans, B.

    2007-01-01

    We study the transition between positive and negative organic magnetoresistance (OMAR) in tris-(8 hydroxyquinoline) aluminium (Alq3), in order to identify the elementary mechanisms governing this phenomenon. We show how the sign of OMAR changes as function of the applied voltage and temperature. The

  17. African Journal of Biotechnology - Vol 12, No 28 (2013)

    African Journals Online (AJOL)

    A thirteen week ad libitum administration toxicity study of tartrazine in Swiss mice · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Nabila Mehedi, Nawel Mokrane, Omar Alami, Soraya Ainad-Tabet, Chahinaize Zaoui, Omar Kheroua, Djamel Saidi ...

  18. A two-step real-time PCR assay for quantitation and genotyping of human parvovirus 4.

    Science.gov (United States)

    Väisänen, E; Lahtinen, A; Eis-Hübinger, A M; Lappalainen, M; Hedman, K; Söderlund-Venermo, M

    2014-01-01

    Human parvovirus 4 (PARV4) of the family Parvoviridae was discovered in a plasma sample of a patient with an undiagnosed acute infection in 2005. Currently, three PARV4 genotypes have been identified, however, with an unknown clinical significance. Interestingly, these genotypes seem to differ in epidemiology. In Northern Europe, USA and Asia, genotypes 1 and 2 have been found to occur mainly in persons with a history of injecting drug use or other parenteral exposure. In contrast, genotype 3 appears to be endemic in sub-Saharan Africa, where it infects children and adults without such risk behaviour. In this study, a novel straightforward and cost-efficient molecular assay for both quantitation and genotyping of PARV4 DNA was developed. The two-step method first applies a single-probe pan-PARV4 qPCR for screening and quantitation of this relatively rare virus, and subsequently, only the positive samples undergo a real-time PCR-based multi-probe genotyping. The new qPCR-GT method is highly sensitive and specific regardless of the genotype, and thus being suitable for studying the clinical impact and occurrence of the different PARV4 genotypes. Copyright © 2013 Elsevier B.V. All rights reserved.

  19. Human parvovirus B19 and parvovirus 4 among Iranian patients with hemophilia.

    Science.gov (United States)

    Javanmard, Davod; Ziaee, Masood; Ghaffari, Hadi; Namaei, Mohammad Hasan; Tavakoli, Ahmad; Mollaei, Hamidreza; Moghoofei, Mohsen; Mortazavi, Helya Sadat; Monavari, Seyed Hamidreza

    2017-12-01

    Human parvovirus B19 (B19V) is one of the smallest DNA viruses and shows great resistance to most disinfectants. Therefore, it is one of the common contaminant pathogens present in blood and plasma products. Parvovirus 4 (PARV4) is a newly identified parvovirus, which is also prevalent in parenteral transmission. In this study, we aimed to evaluate the prevalence of B19V and PARV4 DNA among patients with hemophilia in Birjand County in eastern Iran. This was a cross-sectional epidemiological study comprising nearly all people with hemophilia in this region. Whole blood samples were taken after patient registration and sent for plasma isolation. After nucleic acid extraction, B19V was detected with real-time polymerase chain reaction, PARV4 DNA was then detected using sensitive semi-nested PCR. In total, there were 86 patients with hemophilia, with mean age 28.5±1.5 years. Of these, 90.7% were men and 9.3% women; 84.9% had hemophilia A and 7.0% had hemophilia B. We found 11 patients (12.8%) were positive for B19V DNA and 8 were positive (9.3%) for PARV4 DNA. The prevalence of B19V was higher in middle-aged groups rather than younger people, whereas PARV4 infection was more common in younger patients ( P B19 virus, imposing more precautionary measures for serum and blood products is recommended.

  20. [Detection of human parvovirus B19, human bocavirus and human parvovirus 4 infections in blood samples among 95 patients with liver disease in Nanjing by nested PCR].

    Science.gov (United States)

    Tong, Rui; Zhou, Wei-Min; Liu, Xi-Jun; Wang, Yue; Lou, Yong-Liang; Tan, Wen-Jie

    2013-04-01

    To analyze the infection of human parvovirus B19, human bocavirus (HBoV) and human parvovirus 4 (PARV4) in blood samples among patients with liver disease in Nanjing by molecular detection. Nested PCR assays were designed and validated to detect B19, HBoV and PARV4, respectively. The assays were used to screen three parvoviruses in blood samples from 95 patients with different liver disease in Nanjing. The parvovirus infection was analyzed statistically. The detection limits were 10 copies of genomic DNA equivalents per reaction for each assays and the good specificity were observed. The frequency of B19 and HBoV were 2/95 (2.1%) and 9/95 (9.5%) in blood samples respectively. No PARV4 was detected. HBoV was detected in 3/5 patients with drug-induced hepatitis. Both B19 and HBoV infection were detected in blood from patients with liver disease.

  1. Value and clinical application of orthopedic metal artifact reduction algorithm in CT scans after orthopedic metal implantation

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Yi; Pan, Shinong; Zhao, Xudong; Guo, Wenli; He, Ming; Guo, Qiyong [Shengjing Hospital of China Medical University, Shenyang (China)

    2017-06-15

    To evaluate orthopedic metal artifact reduction algorithm (O-MAR) in CT orthopedic metal artifact reduction at different tube voltages, identify an appropriate low tube voltage for clinical practice, and investigate its clinical application. The institutional ethical committee approved all the animal procedures. A stainless-steel plate and four screws were implanted into the femurs of three Japanese white rabbits. Preoperative CT was performed at 120 kVp without O-MAR reconstruction, and postoperative CT was performed at 80–140 kVp with O-MAR. Muscular CT attenuation, artifact index (AI) and signal-to-noise ratio (SNR) were compared between preoperative and postoperative images (unpaired t test), between paired O-MAR and non-O-MAR images (paired Student t test) and among different kVp settings (repeated measures ANOVA). Artifacts' severity, muscular homogeneity, visibility of inter-muscular space and definition of bony structures were subjectively evaluated and compared (Wilcoxon rank-sum test). In the clinical study, 20 patients undertook CT scan at low kVp with O-MAR with informed consent. The diagnostic satisfaction of clinical images was subjectively assessed. Animal experiments showed that the use of O-MAR resulted in accurate CT attenuation, lower AI, better SNR, and higher subjective scores (p < 0.010) at all tube voltages. O-MAR images at 100 kVp had almost the same AI and SNR as non-O-MAR images at 140 kVp. All O-MAR images were scored ≥ 3. In addition, 95% of clinical CT images performed at 100 kVp were considered satisfactory. O-MAR can effectively reduce orthopedic metal artifacts at different tube voltages, and facilitates low-tube-voltage CT for patients with orthopedic metal implants.

  2. Value and clinical application of orthopedic metal artifact reduction algorithm in CT scans after orthopedic metal implantation

    International Nuclear Information System (INIS)

    Hu, Yi; Pan, Shinong; Zhao, Xudong; Guo, Wenli; He, Ming; Guo, Qiyong

    2017-01-01

    To evaluate orthopedic metal artifact reduction algorithm (O-MAR) in CT orthopedic metal artifact reduction at different tube voltages, identify an appropriate low tube voltage for clinical practice, and investigate its clinical application. The institutional ethical committee approved all the animal procedures. A stainless-steel plate and four screws were implanted into the femurs of three Japanese white rabbits. Preoperative CT was performed at 120 kVp without O-MAR reconstruction, and postoperative CT was performed at 80–140 kVp with O-MAR. Muscular CT attenuation, artifact index (AI) and signal-to-noise ratio (SNR) were compared between preoperative and postoperative images (unpaired t test), between paired O-MAR and non-O-MAR images (paired Student t test) and among different kVp settings (repeated measures ANOVA). Artifacts' severity, muscular homogeneity, visibility of inter-muscular space and definition of bony structures were subjectively evaluated and compared (Wilcoxon rank-sum test). In the clinical study, 20 patients undertook CT scan at low kVp with O-MAR with informed consent. The diagnostic satisfaction of clinical images was subjectively assessed. Animal experiments showed that the use of O-MAR resulted in accurate CT attenuation, lower AI, better SNR, and higher subjective scores (p < 0.010) at all tube voltages. O-MAR images at 100 kVp had almost the same AI and SNR as non-O-MAR images at 140 kVp. All O-MAR images were scored ≥ 3. In addition, 95% of clinical CT images performed at 100 kVp were considered satisfactory. O-MAR can effectively reduce orthopedic metal artifacts at different tube voltages, and facilitates low-tube-voltage CT for patients with orthopedic metal implants

  3. Scanning Cargo Containers with Tagged Neutrons

    International Nuclear Information System (INIS)

    Viesti, G.; Botosso, C.; Fabris, D.; Lunardon, M.; Moretto, S.; Nebbia, G.; Pesente, S.; Zenoni, A.; Donzella, A.; Perot, B.; Carasco, C.; Bernard, S.; Mariani, A.; Szabo, J.-L.; Sannie, G.; Valkovic, V.; Sudac, D.; Nad, K.; Peerani, P.; Sequeira, V.

    2007-01-01

    A new Tagged Neutron Inspection System (TNIS) able to detect illicit materials such as explosives and narcotics in cargo containers has been developed within the EURopean Illicit TRAfficing Countermeasures Kit (EURITRACK) project. After the R and D phase, the inspection portal has been installed and commissioned at the Rijeka seaport in Croatia, where it has been operated in connection with the existing X-ray scanner for a first two-month demonstration campaign. Results obtained are presented and discussed in this paper

  4. Madaket Harbor, Nantucket, Massachusetts. Water Resources Improvement.

    Science.gov (United States)

    1977-07-01

    will continue to be, important increases in the recreational use of land and water. The harbor area is an important arena for commercial shellfishing...an important arena for commercial shell fishing. The past few years have seen a rather rapid increase in residential land use. Construction has...beamc. Tnis material will be re-deposited,, viaj troio it 1-apfro1inr ox prior location. j, MADAKET HARBOR NANTUCKET, MASSACHUSETTS FEASIBILITY

  5. Operational Implications of the NATO Strategic Concept 2010 for European Countries in NATO and the EU

    Science.gov (United States)

    2011-12-01

    tnis von NATO und EU- Eine Analyse unter Beriicksichtigung des Lissabonner Reformvertrages (Munich: AVM-Verlag, 2009), 4. Martin Reichard, The EU-NATO...Lockheed Martin Corp., Moorestown, USA. The consortium developed the first multifunctional counter battery radar in the world with a fu lly active phased...significant forces in expeditionary missions. Gustav Lindstrom , Caaudia Major and Christian Mt>lling provide a good review of the historic background, the

  6. Effect of water deficit on growth and photosynthetic characteristics of ...

    African Journals Online (AJOL)

    Administrator

    2011-09-26

    Sep 26, 2011 ... Danièle Clavel, Omar Diouf, Jean L, Khalfaoui, SB (2006). Genotypes ... chlorophyll fluorescence parameters and carbon isotope discrimination of ... oxygen evolution at low water potential in leaf discs lacking an epidermis.

  7. Jabur jaht Sudaani presidendile / Allan Espenberg

    Index Scriptorium Estoniae

    Espenberg, Allan

    2009-01-01

    Haagis tegutsev Rahvusvaheline Kriminaalkohus andis käsu Sudaani presidendi Omar Hassan Ahmad al-Bashiri vahistamiseks, keda süüdistatakse inimsusevastastes ja sõjakuritegudes ning Darfuri provintsis tsiviilelanike genotsiidi organiseerimises

  8. Pärnu täna : Seegi maja kaks aukirja / Tõnu Kann

    Index Scriptorium Estoniae

    Kann, Tõnu, 1957-

    2001-01-01

    Pärnus Hospidali 1 asuva muinsuskaitsealuse Seegi maja ajaloost ja restaureerimisest tehnik-arhitekti Leevi Soku kontseptsiooni järgi. Maja omanik Raivo Tõnismaa ja sisekujunduse teinud Omar Volmer said tehtud töö eest muinsuskaitse aukirjad

  9. Kohus himustab Sudaani presidenti / Kalev Vilgats

    Index Scriptorium Estoniae

    Vilgats, Kalev

    2009-01-01

    Rahvusvaheline kirminaalkohus otsustas anda välja rahvusvahelise orderi Sudaani presidendi Omar al-Bashir vahistamiseks sõja- ja inimsusevastaste kuritegude eest. Sellekohased arvamused välisajakirjanduses

  10. Gaboni riigipea lahkub presidendipaleest vaid jalad ees / Allan Espenberg

    Index Scriptorium Estoniae

    Espenberg, Allan

    2005-01-01

    Kesk-Aafrika riigi Gaboni president Omar Bongo püüab detsembris toimuvatel presidendivalimistel taotleda enda tagasivalimist. Bongo on juhtinud Gaboni 38 aastat, olles sellega Aafrika riigipeade hulgas kõige staazhikam valitseja

  11. An overview of the prevalence and distribution of gastrointestinal ...

    African Journals Online (AJOL)

    An overview of the prevalence and distribution of gastrointestinal parasitic infections in post-war Iraq. Noor Abdulhaleem, Aliyu Mahmuda, Al-Zihiry Khalid Jameel Khadim, Roslaini Abd Majid, Leslie Than Thian Lung, Wan Omar Abdullah, Zasmy Unyah ...

  12. Characterization of element and mineral content in Artemisia annua ...

    African Journals Online (AJOL)

    Characterization of element and mineral content in Artemisia annua and Camellia sinensis leaves by handheld X-ray fluorescence. Traore Alassane, Diallo Mouhamadou, Gueye Papa El Hadji Omar, Wague Ahmadou, Lutgen Pierre, Sarr Ousmane, Mboup Souleymane ...

  13. Surgical Treatment of Complication of Female Genital Mutilation in ...

    African Journals Online (AJOL)

    Surgical Treatment of Complication of Female Genital Mutilation in Pikine Hospital, Senegal. Abdoul A Diouf, Moussa Diallo, Aissatou Mbodj, Omar Gassama, Mamour Guèye, Jean C Moreau, Alassane Diouf ...

  14. African Journal of Traditional, Complementary and Alternative ...

    African Journals Online (AJOL)

    org/10.21010/ajtcam.v13i6.9 .... Muhammad Abuzar Ghaffari, Bashir Ahmed Chaudhary, Muhammad Uzair, Khuram Ashfaq, 194-198 ... Abdelkader Benhelima, Zohra Kaid-Omar, Houari Hemida, Tarek Benmahdi, Ahmed Addou, 204-214.

  15. Women's Rights in Human Rights Systems: Past, Present and Future ...

    African Journals Online (AJOL)

    Abstract. In the 2009 Dullah Omar Memorial Lecture, United Nations High Commissioner for Human Rights Navanethem Pillay contextualises many of the issues facing women that were raised in earlier articles.

  16. Nanotechnology: Threats and Deterrent Opportunities by 2035

    Science.gov (United States)

    2010-02-17

    22. 17 James Watson and Francis Crick discovered the structure of Deoxyribonucleic acid ( DNA ) in 1953. 18 Self-replication is when nanoscale machine...which then improves researchers’ understanding of critical, computationally intensive fields of study like DNA .17 These complementary scientific and...researchers’ clarity on critical medical issues like Deoxyribonucleic acid ( DNA ). 102 Omar Khayyam, Rubaiyat of Omar Khayyam (NY: Random House, 1947

  17. General of the Army George C. Marshall’s Strategic Leadership

    Science.gov (United States)

    2017-03-15

    Depression to perform conservation tasks in rural areas.31 In 1938, Marshall moved to the War Plans Division of the General Staff. Unbeknownst to...125 US Army Center of Military History, “Omar Nelson Bradley: The Centennial ,” US Army, 2006...Omar Nelson Bradley: The Centennial .” US Army, 2006. Accessed April 2, 2017. http://www.history.army.mil/brochures/bradley/bradley.htm. Watson

  18. Future perspectives and their relation to wellbeing and resilience in adolescents

    OpenAIRE

    Alicia Omar

    2015-01-01

    Previous research (Omar, 2005; Omar, Uribe Delgado & Maltaneres, 2005), had showed a clear relationship between subjective well-being and resilience. In those opportunities, however, resilience was considered as a global construct. This study aims at exploring the possible relationships among resilience components, subjective well-being, and future perspectives. Method: Sample integrated by 198 (105 girls & 93 boys) Argentinean high school students, 14- to 19-yr.-old. All sample parti...

  19. Biosynthesis of acid phosphatase of baker's yeast . Characterization of a protoplast-bound fraction containing precursors of the exo-enzyme

    NARCIS (Netherlands)

    Boer, Pieter; Rijn, Herman J.M. van; Reinking, A.; Steyn-Parvé, Elizabeth P.

    1975-01-01

    1. 1.|Yest protoplasts, secreting acid phosphatase (orthophosphoric-monoester phosphohydrolase (acid optimum) EC 3.1.3.2) contain a small amount of firmly bound enzyme, even after lysis (Van Rijn, H.J.M.; Boer, P. and Steyn-Parvé, E.P. (1972) Biochim. Biophys. Acta 268, 431–441). The major part

  20. No Evidence of Presence of Parvovirus 4 in a Swedish Cohort of Severely Immunocompromised Children and Adults

    Science.gov (United States)

    Tolfvenstam, Thomas; Norbeck, Oscar; Öhrmalm, Lars

    2012-01-01

    The recently discovered human parvovirus 4 (PARV4) has been associated with seropositivity for human immunodeficiency virus, hepatitis B virus and hepatitis C virus. High prevalence is seen especially in intravenous drug users. The virus has been detected in blood products and persons who have been repeatedly transfused have shown to be a risk-group. Furthermore, reports from different parts of the world suggesting a prevalence ranging from zero to one third of the healthy population and the virus is thought to cause a latent or persistent infection. We investigated the presence of PARV4 DNA and parvovirus B19 (B19) DNA in serum from 231 severely immunocompromised cancer patients that have been exposed for blood products. Compared to B19, which was found in 3.9% of the patients, we found no evidence of PARV4. Our results may indicate a very low prevalence of the virus in Sweden, and it would be useful to measure the real PARV4 exposure of the healthy population as well as individuals with known risk factors by serology. PMID:23050026

  1. Novel Parvovirus and Related Variant in Human Plasma

    Science.gov (United States)

    Fryer, Jacqueline F.; Kapoor, Amit; Minor, Philip D.; Delwart, Eric

    2006-01-01

    We report a novel parvovirus (PARV4) and related variants in pooled human plasma used in the manufacture of plasma-derived medical products. Viral DNA was detected by using highly selective polymerase chain reaction assays; 5% of pools tested positive, and amounts of DNA ranged from 106 copies/mL plasma. PMID:16494735

  2. Side relvaliigi rollist kaitseväes / Villem Sedrik

    Index Scriptorium Estoniae

    Sedrik, Villem

    2007-01-01

    Autor annab ülevaate siderelvaliigi arengust kaitseväes ning rõhutab lahinguolukorras erinevate võitlevate partnerite infosüsteemide koostöö ja infovahetuse tähtsust tänapäeval. Vt. ka Sõdur nr. 2 lk. 12-15. Vahur Parve. Kiirpilk sidepidamise ajalukku

  3. Pärnu linnavalitsuse hinnang esimesele valitsemisaastale / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2006-01-01

    Ajaleht esitas Pärnu linnajuhtidele kolm küsimust. Vastasid linnapea Mart Viisitamm, abilinnapea majanduse valdkonnas Raul Sarandi, abilinnapea arengu ja planeerimise valdkonnas Mart Alliku, abilinnapea kultuuri, spordi ja sotsiaalvaldkonnas Margus Tammekivi ja linnavalitsuse liige turvalisuse valdkonnas Simmo Saar. Arvamust avaldavad Reformierakonna Pärnu piirkonna esimees Väino Hallik ja SDE esindaja Pärnu linnavolikogus Valter Parve

  4. Mida võib oletada? = What may we assume? / Indrek Grigor

    Index Scriptorium Estoniae

    Grigor, Indrek, 1981-

    2015-01-01

    Vaadeldakse tänapäevase fotokunsti rahvusvahelist näitust "Aegvõte" Tallinna Kunstihoones, kuraator Anna Laarits ja kujundaja Dénes Farkas. Teoste eksponeerimisest. Näitus toimus "Tallinna Fotokuu 2015" programmi raames. Eestlastest osalesid Ats Parve ja Jüri Okas

  5. Imetabane väljapanek toob Kumu saali kogu maailma looduse kirevuse / Rein Maran

    Index Scriptorium Estoniae

    Maran, Rein, 1931-

    2006-01-01

    Rahvusvahelise fotokonkursi näitusest "Loodusfoto 2005" Kumu suures saalis. Briti Loodusloomuuseumi ja ajakirja BBC Wildlife Magazine korraldatud fotokonkursist. Lähemalt võidutöödest: Alexander Mustard (Suurbritannia) "Riffahvenate parv", Manuel Presti (Itaalia) "Taevane jaht", Bence Mate (Ungari) "Haigutav rebane", Thorsten Milse (Saksamaa) "Polaarretk"

  6. Gossudarstvo berjotsja za energosberezhenije / Andrei Demenkov

    Index Scriptorium Estoniae

    Demenkov, Andrei

    2008-01-01

    31. oktoobril toimunud Majandus- ja kommunikatsiooniministeeriumi energiasäästu temaatilisel foorumil esinesid majandus- ja kommunikatsiooniminister Juhan Parts, energeetika asekantsler Einari Kisel, Säästva energia talituse juhataja Madis Laaniste, Kredexi energiasäästu kompetentsikeskuse projektijuht Heikki Parve ja OÜ Küttemaailm juhatuse esimees Frank Õim

  7. PASSIVE-AVOIDANCE TRAINING INDUCES ENHANCED LEVELS OF IMMUNOREACTIVITY FOR MUSCARINIC ACETYLCHOLINE-RECEPTOR AND COEXPRESSED PKC-GAMMA AND MAP-2 IN RAT CORTICAL-NEURONS

    NARCIS (Netherlands)

    VANDERZEE, EA; DOUMA, BRK; BOHUS, B; LUITEN, PGM

    1994-01-01

    Changes in neocortical immunoreactivity (ir) for muscarinic acetylcholine receptors (mAChRs), protein kinase C gamma (PKC gamma), microtubule-associated protein 2 (MAP-2), and the calcium-binding protein parvalbumin (PARV) induced by the performance of a one-trial passive shock avoidance (PSA) task

  8. Kas ülikoolis õppimine on õige aeg lapse sünnitamiseks? / Ilona Opaal, Liis-Erliken Vinne, Tõnu Ots ... [jt.

    Index Scriptorium Estoniae

    2008-01-01

    Küsimusele vastavad TLÜ anglistikaüliõpilane Ilona Opaal, TLÜ bioloogiaüliõpilane Liis-Erliken Vimme, psühholoog Tõnu Ots, filosoof Valdar Parve, Soome Instituudi direktor Jaana Vasama, psühholoog Tiia Lister, Treffneri Gümnaasiumi usu- ja filosoofiaõpetaja Toomas Jürgenstein

  9. Early Infant Diagnosis of HIV Infection in Southeastern Nigeria ...

    African Journals Online (AJOL)

    METHODS: HIV-exposed infants were recruited for DNA PCR (early infant diagnosis). ... Mothers were given pre-test counselling. ... their mothers received PARV but the babies had no post-exposure prophylaxis (PEP), while two (12.5%) of 16 ...

  10. No evidence of presence of parvovirus 4 in a Swedish cohort of severely immunocompromised children and adults.

    Directory of Open Access Journals (Sweden)

    Thomas Tolfvenstam

    Full Text Available The recently discovered human parvovirus 4 (PARV4 has been associated with seropositivity for human immunodeficiency virus, hepatitis B virus and hepatitis C virus. High prevalence is seen especially in intravenous drug users. The virus has been detected in blood products and persons who have been repeatedly transfused have shown to be a risk-group. Furthermore, reports from different parts of the world suggesting a prevalence ranging from zero to one third of the healthy population and the virus is thought to cause a latent or persistent infection. We investigated the presence of PARV4 DNA and parvovirus B19 (B19 DNA in serum from 231 severely immunocompromised cancer patients that have been exposed for blood products. Compared to B19, which was found in 3.9% of the patients, we found no evidence of PARV4. Our results may indicate a very low prevalence of the virus in Sweden, and it would be useful to measure the real PARV4 exposure of the healthy population as well as individuals with known risk factors by serology.

  11. Poster — Thur Eve — 11: Validation of the orthopedic metallic artifact reduction tool for CT simulations at the Ottawa Hospital Cancer Centre

    International Nuclear Information System (INIS)

    Sutherland, J; Foottit, C

    2014-01-01

    Metallic implants in patients can produce image artifacts in kilovoltage CT simulation images which can introduce noise and inaccuracies in CT number, affecting anatomical segmentation and dose distributions. The commercial orthopedic metal artifact reduction algorithm (O-MAR) (Philips Healthcare System) was recently made available on CT simulation scanners at our institution. This study validated the clinical use of O-MAR by investigating its effects on CT number and dose distributions. O-MAR corrected and uncorrected images were acquired with a Philips Brilliance Big Bore CT simulator of a cylindrical solid water phantom that contained various plugs (including metal) of known density. CT number accuracy was investigated by determining the mean and standard deviation in regions of interest (ROI) within each plug for uncorrected and O-MAR corrected images and comparing with no-metal image values. Dose distributions were calculated using the Monaco treatment planning system. Seven open fields were equally spaced about the phantom around a ROI near the center of the phantom. These were compared to a “correct” dose distribution calculated by overriding electron densities a no-metal phantom image to produce an image containing metal but no artifacts. An overall improvement in CT number and dose distribution accuracy was achieved by applying the O-MAR correction. Mean CT numbers and standard deviations were found to be generally improved. Exceptions included lung equivalent media, which is consistent with vendor specified contraindications. Dose profiles were found to vary by ±4% between uncorrected or O-MAR corrected images with O-MAR producing doses closer to ground truth

  12. Poster — Thur Eve — 11: Validation of the orthopedic metallic artifact reduction tool for CT simulations at the Ottawa Hospital Cancer Centre

    Energy Technology Data Exchange (ETDEWEB)

    Sutherland, J; Foottit, C [The Ottawa Hospital Cancer Centre (Canada)

    2014-08-15

    Metallic implants in patients can produce image artifacts in kilovoltage CT simulation images which can introduce noise and inaccuracies in CT number, affecting anatomical segmentation and dose distributions. The commercial orthopedic metal artifact reduction algorithm (O-MAR) (Philips Healthcare System) was recently made available on CT simulation scanners at our institution. This study validated the clinical use of O-MAR by investigating its effects on CT number and dose distributions. O-MAR corrected and uncorrected images were acquired with a Philips Brilliance Big Bore CT simulator of a cylindrical solid water phantom that contained various plugs (including metal) of known density. CT number accuracy was investigated by determining the mean and standard deviation in regions of interest (ROI) within each plug for uncorrected and O-MAR corrected images and comparing with no-metal image values. Dose distributions were calculated using the Monaco treatment planning system. Seven open fields were equally spaced about the phantom around a ROI near the center of the phantom. These were compared to a “correct” dose distribution calculated by overriding electron densities a no-metal phantom image to produce an image containing metal but no artifacts. An overall improvement in CT number and dose distribution accuracy was achieved by applying the O-MAR correction. Mean CT numbers and standard deviations were found to be generally improved. Exceptions included lung equivalent media, which is consistent with vendor specified contraindications. Dose profiles were found to vary by ±4% between uncorrected or O-MAR corrected images with O-MAR producing doses closer to ground truth.

  13. Clinical evaluation of a commercial orthopedic metal artifact reduction tool for CT simulations in radiation therapy

    Energy Technology Data Exchange (ETDEWEB)

    Li Hua; Noel, Camille; Chen, Haijian; Harold Li, H.; Low, Daniel; Moore, Kevin; Klahr, Paul; Michalski, Jeff; Gay, Hiram A.; Thorstad, Wade; Mutic, Sasa [Department of Radiation Oncology, Washington University, St. Louis, Missouri 63110 (United States); Department of Radiation Oncology, University of California Los Angeles, Los Angeles, California 90095 (United States); Department of Radiation Oncology, University of California San Diego, San Diego, California 92093 (United States); Philips Healthcare System, Cleveland, Ohio 44143 (United States); Department of Radiation Oncology, Washington University, St. Louis, Missouri 63110 (United States)

    2012-12-15

    Purpose: Severe artifacts in kilovoltage-CT simulation images caused by large metallic implants can significantly degrade the conspicuity and apparent CT Hounsfield number of targets and anatomic structures, jeopardize the confidence of anatomical segmentation, and introduce inaccuracies into the radiation therapy treatment planning process. This study evaluated the performance of the first commercial orthopedic metal artifact reduction function (O-MAR) for radiation therapy, and investigated its clinical applications in treatment planning. Methods: Both phantom and clinical data were used for the evaluation. The CIRS electron density phantom with known physical (and electron) density plugs and removable titanium implants was scanned on a Philips Brilliance Big Bore 16-slice CT simulator. The CT Hounsfield numbers of density plugs on both uncorrected and O-MAR corrected images were compared. Treatment planning accuracy was evaluated by comparing simulated dose distributions computed using the true density images, uncorrected images, and O-MAR corrected images. Ten CT image sets of patients with large hip implants were processed with the O-MAR function and evaluated by two radiation oncologists using a five-point score for overall image quality, anatomical conspicuity, and CT Hounsfield number accuracy. By utilizing the same structure contours delineated from the O-MAR corrected images, clinical IMRT treatment plans for five patients were computed on the uncorrected and O-MAR corrected images, respectively, and compared. Results: Results of the phantom study indicated that CT Hounsfield number accuracy and noise were improved on the O-MAR corrected images, especially for images with bilateral metal implants. The {gamma} pass rates of the simulated dose distributions computed on the uncorrected and O-MAR corrected images referenced to those of the true densities were higher than 99.9% (even when using 1% and 3 mm distance-to-agreement criterion), suggesting that dose

  14. Reduction of artifacts caused by orthopedic hardware in the spine in spectral detector CT examinations using virtual monoenergetic image reconstructions and metal-artifact-reduction algorithms

    Energy Technology Data Exchange (ETDEWEB)

    Grosse Hokamp, Nils; Neuhaus, V.; Abdullayev, N.; Laukamp, K.; Lennartz, S.; Mpotsaris, A.; Borggrefe, J. [University Hospital Cologne, Department of Diagnostic and Interventional Radiology, Cologne (Germany)

    2018-02-15

    Aim of this study was to assess the artifact reduction in patients with orthopedic hardware in the spine as provided by (1) metal-artifact-reduction algorithms (O-MAR) and (2) virtual monoenergetic images (MonoE) as provided by spectral detector CT (SDCT) compared to conventional iterative reconstruction (CI). In all, 28 consecutive patients with orthopedic hardware in the spine who underwent SDCT-examinations were included. CI, O-MAR and MonoE (40-200 keV) images were reconstructed. Attenuation (HU) and noise (SD) were measured in order to calculate signal-to-noise ratio (SNR) of paravertebral muscle and spinal canal. Subjective image quality was assessed by two radiologists in terms of image quality and extent of artifact reduction. O-MAR and high-keV MonoE showed significant decrease of hypodense artifacts in terms of higher attenuation as compared to CI (CI vs O-MAR, 200 keV MonoE: -396.5HU vs. -115.2HU, -48.1HU; both p ≤ 0.001). Further, artifacts as depicted by noise were reduced in O-MAR and high-keV MonoE as compared to CI in (1) paravertebral muscle and (2) spinal canal - CI vs. O-MAR/200 keV: (1) 34.7 ± 19.0 HU vs. 26.4 ± 14.4 HU, p ≤ 0.05/27.4 ± 16.1, n.s.; (2) 103.4 ± 61.3 HU vs. 72.6 ± 62.6 HU/60.9 ± 40.1 HU, both p ≤ 0.001. Subjectively both O-MAR and high-keV images yielded an artifact reduction in up to 24/28 patients. Both, O-MAR and high-keV MonoE reconstructions as provided by SDCT lead to objective and subjective artifact reduction, thus the combination of O-MAR and MonoE seems promising for further reduction. (orig.)

  15. Bangor International/Dow AFB, Maine. Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A-F.

    Science.gov (United States)

    1981-11-06

    temporary site at ground GM1-1l RO-2 Surfac level in ramp area. 6 Apr 60 Located approx 200 ft from corner Same RO-2A 13 ft of old rnwy 33 taxiway and...USAF STAC . 0-14-S( OL A) ............ . . .T... ..O . PORN ... 17- GLCPAL CLIMATOLOGY 9RANCH ArETAC CEILING VERSUS VISIBILITY Alq WEATHEk SERVICL/4AC S...13.1 i ?6 6.. 5918 USAFETAC PORN 0.9.5 (OL.-) PFVIOUS EDITIONS OF TnIS FORM AIRE ORSOLTE Jut 64 GLCRAL CLIMAT0L.i Y 1 ANCH AFE T AC SKYCO E A>4 4ATHER

  16. Review and Evaluation of Army Aviation Depot NDI (Nondestructive Inspection) and Reliability Centered Maintenance

    Science.gov (United States)

    1988-08-31

    TAILBOOM ATTACH FITTINC UPPER & LOWER RH 2n _3 S C Y J D U R FUELL CELL AFT BULKHEAD PANEl. R/H Ib 54 S C Y J D U R FUEL CELL UPPER OUTBOARD PANEL R/H...in the real world. terns i-n tnis cIass are generally simple (so-called "sg- cell ") components such as tarts wich are subject to metal ’atizue or otner...AH-64 airframe, the automated airframe logbooK, the upgraded RCA data base management system, the ACE/AACE, CFD, PEM , breakout and other programs as

  17. Fatigue 󈨛. Papers presented at the International Conference on Fatigue and Fatigue Threshold (3rd) Held in Charlottesville, Virginia on June 28-July 3, 1987. Volume 3.

    Science.gov (United States)

    1987-10-15

    rI ONAL 2/6 UNCLASSIFIED P" 4140 fPh ICNlLjG UN rwPLI/6.1 ML. 111111.03128 I2.2 11-1 111112 11.8 IIIJIL25 .4 MICROCOPY RESOLUTION TEST CHART NATIONAL...interval. Tnis strain data was then fitted by ARMA models. The material selected was SAE bolt steel, grade 2. The ultimate strength of this steel is 74 Ksi...2 K. Iwamoto ; JSAE Symp.(1978). 3 H. Kitagawa, T. Satoh and M. Fujimoto ; SAE 850371 (1985) 4 Fujimoto ; JSAE Symp (1985). 5 J. Niizawa, Tomioka,et

  18. Instructor/Operator Display Evaluation Methods

    Science.gov (United States)

    1981-03-01

    d. II nec..aory amd cidentify by bl-i k ,br ( HI Ihq .~Ida 9. high? 9.Iii-/iprldU orm i i 20. ABSTRACT (Continue on revere@ aid. If necessary and...stuay scooe, anu summ.inizeu primary stuoy tecnnimques, u.;eu, din inOUt’outULt arainete~rs, SPOCidl CupauiliT-ie𔃽 , ano limii td -imnsa onu ru 126...ouservations in tnis uiscussion) out, on tne otner odnu, it wuulu weaken any tenuency to td <e seriously tne overall performadnce uifference in favor- ol

  19. Evaluation of Orthopedic Metal Artifact Reduction Application in Three-Dimensional Computed Tomography Reconstruction of Spinal Instrumentation: A Single Saudi Center Experience.

    Science.gov (United States)

    Ali, Amir Monir

    2018-01-01

    The aim of the study was to evaluate the commercially available orthopedic metal artifact reduction (OMAR) technique in postoperative three-dimensional computed tomography (3DCT) reconstruction studies after spinal instrumentation and to investigate its clinical application. One hundred and twenty (120) patients with spinal metallic implants were included in the study. All had 3DCT reconstruction examinations using the OMAR software after obtaining the informed consents and approval of the Institution Ethical Committee. The degree of the artifacts, the related muscular density, the clearness of intermuscular fat planes, and definition of the adjacent vertebrae were qualitatively evaluated. The diagnostic satisfaction and quality of the 3D reconstruction images were thoroughly assessed. The majority (96.7%) of 3DCT reconstruction images performed were considered satisfactory to excellent for diagnosis. Only 3.3% of the reconstructed images had rendered unacceptable diagnostic quality. OMAR can effectively reduce metallic artifacts in patients with spinal instrumentation with highly diagnostic 3DCT reconstruction images.

  20. Evaluation of the reconstruction of image acquired from CT simulator to reduce metal artifact

    International Nuclear Information System (INIS)

    Choi, Ji Hun; Park, Jin Hong; Choi, Byung Don; Won, Hui Su; Chang, Nam Jun; Goo, Jang Hyun; Hong, Joo Wan

    2014-01-01

    This study presents the usefulness assessment of metal artifact reduction for orthopedic implants(O-MAR) to decrease metal artifacts from materials with high density when acquired CT images. By CT simulator, original CT images were acquired from Gammex and Rando phantom and those phantoms inserted with high density materials were scanned for other CT images with metal artifacts and then O-MAR was applied to those images, respectively. To evaluate CT images using Gammex phantom, 5 regions of interest(ROIs) were placed at 5 organs and 3 ROIs were set up at points affected by artifacts. The averages of standard deviation(SD) and CT numbers were compared with a plan using original image. For assessment of variations in dose of tissue around materials with high density, the volume of a cylindrical shape was designed at 3 places in images acquired from Rando phantom by Eclipse. With 6 MV, 7-fields, 15x15cm 2 and 100 cGy per fraction, treatment planning was created and the mean dose were compared with a plan using original image. In the test with the Gammex phantom, CT numbers had a few difference at established points and especially 3 points affected by artifacts had most of the same figures. In the case of O-MAR image, the more reduction in SD appeared at all of 8 points than non O-MAR image. In the test using the Rando Phantom, the variations in dose of tissue around high density materials had a few difference between original CT image and CT image with O-MAR. The CT images using O-MAR were acquired clearly at the boundary of tissue around high density materials and applying O-MAR was useful for correcting CT numbers

  1. Pidupäevaüritused olid Eestile ilus kingitus / Andris Tammela, Eno-Gerrit Link

    Index Scriptorium Estoniae

    Tammela, Andris

    2008-01-01

    Ülevaade EV 90. aastapäeva juubeliüritusest Pärnus. Vt. samas: Vabariigi juubel värvis Pärnu sinimustvalgeks; Head emotsioonid Eesti aastapäevalt: Are vallavanem Jaanus Männik, Euroopa Parlamendi liige Marianne Mikko, Pärnu linnavolikogu liikmed Valter Parve ja Raul Sarandi ja Pärnu maavanem Toomas Kivimägi

  2. Maailma loodusfoto Kumus

    Index Scriptorium Estoniae

    2006-01-01

    18.10-12.11 Kumu Kunstimuuseumis avatud 80 loodusfoto näitus, mille korraldajad olid Briti Loodusloomuuseum ja ajakiri BBC Wildlife Magazine. Illustratsioonidena "Loodusfoto 2005" üldvõitja Manuel Presti "Taevane jaht", loomaportreede kategooria võitja Alexander Mustard'i "Riffahvenate parv", imetajate käitumise kategooria II koht Thorsten Milse "Polaarretk" ja noortele fotograafidele mõeldud Eric Hoskingi kategooria võitja Bence Maté "Haigutav rebane"

  3. Inhibition of GABA synthesis in the prefrontal cortex increases locomotor activity but does not affect attention in the 5-choice serial reaction time task

    OpenAIRE

    Asinof, Samuel K.; Paine, Tracie A.

    2012-01-01

    Attention deficits are a core cognitive symptom of schizophrenia; the neuropathology underlying these deficits is not known. Attention is regulated, at least in part, by the prefrontal cortex (PFC), a brain area in which pathology of γ-aminobutyric acid (GABA) neurons has been consistently observed in post-mortem analysis of the brains of people with schizophrenia. Specifically, expression of the 67-kD isoform of the GABA synthesis enzyme glutamic acid decarboxylase (GAD67) is reduced in parv...

  4. Evaluating the Efficacy of ERG Targeted Therapy in vivo for Prostate Tumors

    Science.gov (United States)

    2016-06-01

    Arvin M. Gouw, Meital Gabay, Stacey J. Adam, David I. Bellovin, Phuoc T. Tran, William M. Philbricke, Adolfo Garcia-Ocanaf, Stephanie C. Casey, Yulin Li ...2016). In press. PMID: 27080744. 4. Abstracts (Year 5 only from a total of 47 since the beginning of the DoD PRTA): 1. Omar Y. Mian , Scott Robertson...Meeting. 2. Omar Y. Mian , Scott Robertson, Amol Narang, Sameer Agarwal, Hee Joon Bae, Todd McNutt, Phuoc Tran, Theodore L. DeWeese, Danny Y. Song

  5. Evaluating applicability of metal artifact reduction algorithm for head and neck radiation treatment planning CT

    International Nuclear Information System (INIS)

    Son, Sang Jun; Park, Jang Pil; Kim, Min Jeong; Yoo, Suk Hyun

    2014-01-01

    The purpose of this study is evaluation for the applicability of O-MAR(Metal artifact Reduction for Orthopedic Implants)(ver. 3.6.0, Philips, Netherlands) in head and neck radiation treatment planning CT with metal artifact created by dental implant. All of the in this study's CT images were scanned by Brilliance Big Bore CT(Philips, Netherlands) at 120 kVp, 2 mm sliced and Metal artifact reduced by O-MAR. To compare the original and reconstructed CT images worked on RTPS(Eclipse ver 10.0.42, Varian, USA). In order to test the basic performance of the O-MAR, The phantom was made to create metal artifact by dental implant and other phantoms used for without artifact images. To measure a difference of HU in with artifact images and without artifact images, homogeneous phantom and inhomogeneous phantoms were used with cerrobend rods. Each of images were compared a difference of HU in ROIs. And also, 1 case of patient's original CT image applied O-MAR and density corrected CT were evaluated for dose distributions with SNC Patient(Sun Nuclear Co., USA). In cases of head and neck phantom, the difference of dose distribution is appeared 99.8% gamma passing rate(criteria 2 mm / 2%) between original and CT images applied O-MAR. And 98.5% appeared in patient case, among original CT, O-MAR and density corrected CT. The difference of total dose distribution is less than 2% that appeared both phantom and patient case study. Though the dose deviations are little, there are still matters to discuss that the dose deviations are concentrated so locally. In this study, The quality of all images applied O-MAR was improved. Unexpectedly, Increase of max. HU was founded in air cavity of the O-MAR images compare to cavity of the original images and wrong corrections were appeared, too. The result of study assuming restrained case of O-MAR adapted to near skin and low density area, it appeared image distortion and artifact correction simultaneously. In O-MAR CT, air cavity area

  6. E. P. Thompson, un marxista contra el marxismo como “materialismo histórico”

    OpenAIRE

    Omar Acha

    2013-01-01

    Análisis de la obra de Thompson como historiador marxista. Fil: Acha, José Omar. Consejo Nacional de Invest.cientif.y Tecnicas. Oficina de Coordinacion Administrativa Saavedra 15. Instituto de Historia Argentina y Americana "dr. Emilio Ravignani";

  7. African Journal of Biotechnology - Vol 11, No 104 (2012)

    African Journals Online (AJOL)

    Screening of antibacterial and antifungal activities in green and brown algae from the coast of Sidi Bouzid (El Jadida, Morocco) · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Khadija Oumaskour, Nabila Boujaber, Samira Etahiri, Omar Assobhei, 16831-16837 ...

  8. Bulletin of Materials Science | News

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 39; Issue 5. Effects of size on mass density and its influence on mechanical and thermal properties of ZrO 2 nanoparticles in different structures. BOTAN JAWDAT ABDULLAH QING JIANG MUSTAFA SAEED OMAR. Volume 39 Issue 5 September 2016 pp 1295-1302 ...

  9. Libyan Journal of Medicine - Vol 12, No 1 (2017)

    African Journals Online (AJOL)

    Computational identification of mutually homologous Zika virus miRNAs that target microcephaly genes · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Ewen McLean, Roshan Bhattarai, Brandon W. Hughes, Kuhanandha Mahalingam, Omar Bagasra.

  10. Intersectionality as Education Policy Reform: Creating Schools That Empower Telling

    Science.gov (United States)

    Beck, Brittney

    2017-01-01

    Brittney Beck wrote this commentary two days after the act of terror and hate that occurred at Pulse in Orlando, Florida in which Omar Mateen murdered 50 people at a queer night club during a celebration of LatinX cultures and identities. Historians have long observed that social movements are preceded by tragedy. Anyon (2014) argued that schools…

  11. Quantitative analysis of orthopedic metal artefact reduction in 64-slice computed tomography scans in large head metal-on-metal total hip replacement, a phantom study

    NARCIS (Netherlands)

    Boomsma, Martijn F.; Warringa, Niek; Edens, Mireille A.; Mueller, Dirk; Ettema, Harmen B.; Verheyen, Cees C. P. M.; Maas, Mario

    2016-01-01

    Purpose: Quantification of the effect of O-MAR on decreasing metal artefacts caused by large head metal on metal total hip arthroplasty (MoM THA) in a dedicated phantom setup of the hip. Background: Pathological reactions of the hip capsule on Computed tomography (CT) can be difficult to diagnose

  12. The Game of Peace and Justice in Sudan

    DEFF Research Database (Denmark)

    Laugesen, Henrik

    Den internationale strafferetsdomstol udsendte i marts 2009 en arrestordre på Sudans præsident Omar al-Bashir. Det internationale samfund har siden været delt på spørgsmålet om arrestordrens konsekvenser og betydning i forhold til at skabe fred og stabilitet i Sudan. I dette brief analyserer majo...

  13. Browse Title Index

    African Journals Online (AJOL)

    Items 51 - 100 of 136 ... Vol 38, No 1 (2018), Short communications: Notes on breeding, ... Preliminary checklists for two Important Bird Areas of Ethiopia: Sof Omar and ... Recommendation to remove the Somali Bee-eater Merops revoilii from the ...

  14. Yaşar Yakiş: see on Kairo 2011, mitte Teheran 1979 / intervjueerinud Priit Simson

    Index Scriptorium Estoniae

    Yakiş, Yaşar

    2011-01-01

    Intervjuu Türgi endise peaministri ja Egiptuse-suursaadikuga Egiptuse rahutuste taustast, president Hosni Mubarakist, asepresident Omar Suleimanist, Muslimi Vennaskonnast, sõjaväe positisioonist Egiptuses. Tema arvates on Egiptus jõudnud punkti, kust tagasipöördumist ei ole, kuid see uus ei tarvitse muutuda vastupidiseks võrreldes praeguse režiimiga

  15. Effect of olive meal and supplemental enzymes on performance ...

    African Journals Online (AJOL)

    Proofreader

    2017-09-29

    Sep 29, 2017 ... The evaluated carcass traits and meat ..... with those of Omar (2005), who found that adding up to 10% of olive pulp in broiler diet had no significant ... In healthy chickens, the caecal microbiota plays an important role in ...

  16. Research Article Special Issue

    African Journals Online (AJOL)

    lanez

    2018-01-15

    Jan 15, 2018 ... of PSO-GA. In H. Fujita, A. Selamat, & H. Haron (Eds.), Frontiers in artificial intelligence and applications. Amsterdam: IOS Press, 2014, pp. 495-512. [8] Masrom S, Abidin S Z Z, Omar N. Easy and concise programming for low-level hybridization of PSO-GA. In International Conference on Intelligent Software ...

  17. Kolm küsimust Rait Pärgile / Rait Pärg ; interv. Katrin Nielsen

    Index Scriptorium Estoniae

    Pärg, Rait

    2001-01-01

    Skulptor Rait Pärg Pärnu skulptuurikaardi ja selle põhjal skulptuurikontseptsiooni koostamisest (osalevad ka Omar Volmer ja Mark Soosaar), 2.-11. juunini korraldatavatest skulptuuripäevadest "Pärnu - positiivse märgiga linn"

  18. An Introduction to the Conjugate Gradient Method that Even an Idiot Can Understand

    Science.gov (United States)

    1994-03-07

    to Omar Ghattas, who taught me much of what I know about numerical methods, and provided me with extensive comments on the first draft of this article...Dongarra, Victor Eijkhout, Roldan Pozo, Charles Romine, and Henk van der Vorst, Templates for the solution of linear systems: Building blocks for iterative

  19. Assessing birth asphyxia using strictly observational signs, the ARC ...

    African Journals Online (AJOL)

    developed by Dr Sultan Omar Sultan was pre-tested at St Francis Hospital Ifakara in 2008 , then tested on 340 newborns in Temeke Hospital and Mnazi Mmoja Hospital. It was found be more sensitive, more specific and more reliable and ultimately ...

  20. Body Fat Content, Distribution and Blood Glucose Concentration ...

    African Journals Online (AJOL)

    disease and 2% are due to Diabetes mellitus, 9% ... study was to examine the relationship between body fat content, ..... A meta-analysis of prospective studies. ... A.A.1., Esterhuizen, T., Gouws, E.,. Pirie, F.J., Omar, M.A. (2008). Diabetes.

  1. Browse Title Index

    African Journals Online (AJOL)

    Items 251 - 300 of 461 ... LN Wangai, M Geoffrey, S Omar, G Magoma, FT Kimani, JM Mwangi, MW ... from blood culture samples of suspected typoid patients in Warri, Nigeria, Abstract PDF ... Staphylococcus aureus in University of Abuja Teaching Hospital, Abuja, ... Vol 17, No 3 (2016), Performance characteristics of enzyme ...

  2. How to reconcile the African Union and the International Criminal Court?

    NARCIS (Netherlands)

    Knottnerus, Abel

    2012-01-01

    Recent years have shown a mounting tension between the African Union and the International Criminal Court. Since the Prosecutor announced on 14 July 2008, that he would request the Court’s Pre-Trial Chamber to issue an arrest warrant for Sudan’s President Omar Al-Bashir, the African Union has

  3. African Journal of Biotechnology - Vol 12, No 26 (2013)

    African Journals Online (AJOL)

    Characterization of element and mineral content in Artemisia annua and Camellia sinensis leaves by handheld X-ray fluorescence · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Traore Alassane, Diallo Mouhamadou, Gueye Papa El Hadji Omar, Wague Ahmadou, ...

  4. Pimedad ööd kutsuvad häid filme vaatama / Kaido Soom

    Index Scriptorium Estoniae

    Soom, Kaido

    2008-01-01

    12. Pimedate Ööde filmifestivali filmidest, mis jätsid sügavama mulje artikli autorile - Taani mängufilm "Mine rahus, Jamil" (rezh. Omar Shargawi), Suurbritannia -Itaalia - Saksamaa - Hispaania - Poola koostööfilm "See on vaba maailm" (rezh. Ken Loach) ja Šveitsi dokumentaalfilm "Tagane, saatan" (rezh. Peter Entell)

  5. On the role of minority carriers in the frequency dependence of organic magnetoresistance

    NARCIS (Netherlands)

    Janssen, Paul; Wagemans, W.; Verhoeven, Wouter; van der Heijden, E.H.M.; Kemerink, M.; Koopmans, B.

    2011-01-01

    In this work we investigate the frequency dependence of organic magnetoresistance (OMAR) both in small molecule-based (Alq3) and polymer (PPV derivative) materials, and investigate its thickness dependence. For all devices, we observed a strong decrease in magnetoconductance (MC) with increasing

  6. 75 FR 35815 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2010-06-23

    ..., TX 76011. Officers: Omar Kolaghassi, Manager (Qualifying Individual), Laura Alicia, Manager. Application Type: New OFF & NVO License. CALS Logistics USA, Inc. (OFF & NVO), 755 North Route 83, Suite 215.... Premium Star Logistics LLC dba O.P. Premium Star Logistics (OFF & NVO), 4200 Lightning Court, Bakersfield...

  7. Külas tippterroristil / Aadu Hiietamm

    Index Scriptorium Estoniae

    Hiietamm, Aadu, 1954-

    2006-01-01

    Briti nädalaajalehe The Sunday Times artiklist, milles kirjeldatakse Iraagi sunniitide vastupanuliikumise ühe juhi šeik Abu Omar al Ansari kohtumist Iraagis enim tagaotsitava terroristi Abu Musab al-Zarqawi'ga, et arutada koostööd okupatsioonijõudude ründamisel

  8. Browse Title Index

    African Journals Online (AJOL)

    Items 401 - 450 of 1178 ... Y-X Zhou, J Chen, J-P Li, Y-L Wang, X-D Jin ... Vol 4, No 3 (2007), Comparative Chemical And Analgesic Properties Of Essential Oils ... Pilar Carranza-Rosales, Omar Heredia-Rodríguez, Gerardo Lozano-Garza, Angel ...

  9. What French for Gabonese French Lexicography

    African Journals Online (AJOL)

    user

    administration, international relations, teaching, the media, trade, transport, tourism, .... The present study refutes such as reductive definition of what Gabonese .... language than French limits itself to public speeches and support to linguistics ...... sité Omar Bongo du Gabon: Série Lettres, Droit, Sciences et Médecine: 55-63.

  10. Cultural Emergency in Conflict and Disaster

    NARCIS (Netherlands)

    Frerks, G.E.; Klein Goldewijk, B.

    2011-01-01

    All that we're wrecking is stones" was Taliban leader Mullah Mohammed Omar's dismissal of the Taliban's destruction of the Buddhas of Bamyan, the largest standing statues of Buddha in the world. The intention of the fighters was not only the destruction of foreign idols, but breaking the soul of a

  11. Preliminary checklists for two Important Bird Areas of Ethiopia: Sof ...

    African Journals Online (AJOL)

    Ethiopia harbours 837 bird species, 18 of which are endemic and a further 14 near endemic (shared ... of these IBAs. Sof Omar (6°54' N, 40°47' E; 1150–1450 m) and Shek Husein (7°50' N, 40°35 E; c. ... They were more slender than other swifts, and darker than African .... Grey-backed Camaroptera Camaroptera brachyura.

  12. 1 Fighting Child Sexual Abuse in Zanzibar through Provision and ...

    African Journals Online (AJOL)

    Elibrary

    sexual harassment, child labour and general exploitation (Kijo-Bisimba, 2013). A survey on violence against ..... internet. The current study's findings concurs with those from a study by Omar (2014) which noted that today's students tend to rely more on online information than on physical information resources. Data from ...

  13. H T Taha

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. H T Taha. Articles written in Sadhana. Volume 35 Issue 2 April 2010 pp 177-193. Effects of nanoscale size dependent parameters on lattice thermal conductivity in Si nanowire · M S Omar H T Taha · More Details Abstract Fulltext PDF. The effects of nanoscale size dependent parameters on lattice ...

  14. Development of a competitive PCR assay for the quantification of ...

    African Journals Online (AJOL)

    ONOS

    2010-01-25

    Jan 25, 2010 ... quantification of total Escherichia coli DNA in water. Omar Kousar Banu, Barnard .... Thereafter the product was ligated into the pGEM®T-easy cloning ... agarose gel using the high pure PCR product purification kit. (Roche® ...

  15. The Harmon Memorial Lectures in Military History 1959-1987

    Science.gov (United States)

    1988-01-01

    Farrand, ed., Records of the Federal Convention of 1787 (New Haven, 1911-1937), 111, 85, 86n. 4. Pogue, Marshall, 1, 323; Larry 1. Bland and Sharon R...569, iU2, 573 Boulogne camp: 316, 317 594 INDEX Bourke , John G.: 26 Chamberlain, Neville: 572 Bradley, Omar N.: 163, 166, 167, 185, 190, Charles

  16. African Journal of Biotechnology - Vol 11, No 45 (2012)

    African Journals Online (AJOL)

    Molecular and pathological identification of feline coronavirus type I · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Alazawy Amer, Arshad Siti-Suri, Hair-Bejo Mohd, Omar Abdul-Rahman, Tengku-Ibrahim Tengku-Azmi, Bande Faruku, Assumaidaee Ajwad, 10451- ...

  17. Wangai et al., Afr. J. Infect. Dis. (2011) 5(1): 1 - 6 SENSITIVITY OF ...

    African Journals Online (AJOL)

    AJTCAM

    Wangai et al., Afr. J. Infect. Dis. (2011) 5(1): 1 - 6. 1. SENSITIVITY OF MICROSCOPY COMPARED TO MOLECULAR DIAGNOSIS OF P. FALCIPARUM: IMPLICATIONS ON MALARIA TREATMENT IN EPIDEMIC AREAS IN. KENYA. Laura Nyawira Wangai 1,2, Muriira Geoffrey Karau 3, Paul Nthakanio Njiruh 4, Omar Sabah 5 ...

  18. Peronism and Youth. Returning to the origins.

    Directory of Open Access Journals (Sweden)

    Maria Luz Silva Calleja

    2014-12-01

    Full Text Available This text is a book review of Argentine historian Omar Acha published in Argentina in 2011, which addresses the organizational processes of the Peronist Youth during the first and second presidency of Perón and later forgetfulness or denial.

  19. Conjunctions in Argumentative Writing of Libyan Tertiary Students

    Science.gov (United States)

    Hamed, Muftah

    2014-01-01

    The aim of this study was an attempt to investigate the use of conjunctions in argumentative essays written by English as a Foreign Language fourth-year undergraduate Libyan students majoring in English at Omar Al-Mukhtar University in Libya. A corpus of 32 argumentative essays was collected from a sample of 16 students in order to be investigated…

  20. The influences of reproductive status and acute stress on the levels of phosphorylated mu opioid receptor immunoreactivity in rat hippocampus

    Directory of Open Access Journals (Sweden)

    Keith L. Gonzales

    2011-08-01

    Full Text Available Opioids play a critical role in hippocampally dependent behavior and plasticity. In the hippocampal formation, mu opioid receptors (MOR are prominent in parvalbumin (PARV containing interneurons. Previously we found that gonadal hormones modulate the trafficking of MORs in PARV interneurons. Although sex differences in response to stress are well documented, the point at which opioids, sex and stress interact to influence hippocampal function remains elusive. Thus, we used quantitative immunocytochemistry in combination with light and electron microscopy for the phosphorylated MOR at the SER375 carboxy-terminal residue (pMOR in male and female rats to assess these interactions. In both sexes, pMOR-immunoreactivity (ir was prominent in axons and terminals and in a few neuronal somata and dendrites, some of which contained PARV in the mossy fiber pathway region of the dentate gyrus (DG hilus and CA3 stratum lucidum. In unstressed rats, the levels of pMOR-ir in the DG or CA3 were not affected by sex or estrous cycle stage. However, immediately following 30 minutes of acute immobilization stress (AIS, males had higher levels of pMOR-ir whereas females at proestrus and estrus (high estrogen stages had lower levels of pMOR-ir within the DG. In contrast, the number and types of neuronal profiles with pMOR-ir were not altered by AIS in either males or proestrus females. These data demonstrate that although gonadal steroids do not affect pMOR levels at resting conditions, they are differentially activated both pre- and post-synaptic MORs following stress. These interactions may contribute to the reported sex differences in hippocampally dependent behaviors in stressed animals.

  1. Specific reactions of different striatal neuron types in morphology induced by quinolinic acid in rats.

    Directory of Open Access Journals (Sweden)

    Qiqi Feng

    Full Text Available Huntington's disease (HD is a neurological degenerative disease and quinolinic acid (QA has been used to establish HD model in animals through the mechanism of excitotoxicity. Yet the specific pathological changes and the underlying mechanisms are not fully elucidated. We aimed to reveal the specific morphological changes of different striatal neurons in the HD model. Sprague-Dawley (SD rats were subjected to unilaterally intrastriatal injections of QA to mimic the HD model. Behavioral tests, histochemical and immunhistochemical stainings as well as Western blots were applied in the present study. The results showed that QA-treated rats had obvious motor and cognitive impairments when compared with the control group. Immunohistochemical detection showed a great loss of NeuN+ neurons and Darpp32+ projection neurons in the transition zone in the QA group when compared with the control group. The numbers of parvalbumin (Parv+ and neuropeptide Y (NPY+ interneurons were both significantly reduced while those of calretinin (Cr+ and choline acetyltransferase (ChAT+ were not changed notably in the transition zone in the QA group when compared to the controls. Parv+, NPY+ and ChAT+ interneurons were not significantly increased in fiber density while Cr+ neurons displayed an obvious increase in fiber density in the transition zone in QA-treated rats. The varicosity densities of Parv+, Cr+ and NPY+ interneurons were all raised in the transition zone after QA treatment. In conclusion, the present study revealed that QA induced obvious behavioral changes as well as a general loss of striatal projection neurons and specific morphological changes in different striatal interneurons, which may help further explain the underlying mechanisms and the specific functions of various striatal neurons in the pathological process of HD.

  2. Multikultuurne testimeeskond / Elver Loho

    Index Scriptorium Estoniae

    Loho, Elver

    2008-01-01

    Tööst multikultuurses kollektiivis räägivad Videobeti Tallinna kontoris töötavad Mehmet Özekinci, Peter Cercone, Vivek Tyagi, Hua Zhong, Mati Parv ja Karpo Korõtko. Videobet on Playtech Groupi kuuluv rahvusvaheline tarkvarafirma, mis on spetsialiseerunud mänguterminalide ning vastavate haldusrakenduste loomisele. Vt. samas: Quebeclane, kes elab Soomes ja töötab Eestis. Artec Groupis äriarendusjuhina töötavast Martin-Eric Racine'ist. Täielikult Eesti kapitalil põhinev Artec tegeleb spetsiifiliste riistvaralahenduste loomisega

  3. Kiviõli linnaväljaku avalik arhitektuurivõistlus = Kiviõli town square open architecture competition / Tiit Sild

    Index Scriptorium Estoniae

    Sild, Tiit, 1977-

    2006-01-01

    Arhitektuurivõistluse eesmärgist, premeeritud töödest. Tulemused: I preemia - Tiina Skolimowski, Kai Süda, Risto Parve, töö "Figuur", II - Karli Luik, Ralf Lõoke, Maarja Kask (AB Salto), töö "Saarestik", III - Jaak-Adam Looveer, Toomas Paaver, Lauri Saar, Indrek Järve, Tõnu Laanemäe (AB Paik Arhitektid), töö "Mult", ergutuspreemia - Ott Kadarik, Villem Tomiste, Mihkel Tüür, Kaiko Kivi, Krista Saluveer (AB Kosmos), töö "Sammal"

  4. Mustamäe Maarja Magdaleena kiriku arhitektuurivõistlus = Architecture competition for Mustamäe`s Church of Mary Magdalene / Pille Epner

    Index Scriptorium Estoniae

    Epner, Pille

    2013-01-01

    Arhitektuurikonkursist, võidutööst "Fiat Lux" (arhitektid Risto Parve, Kai Süda, Martin Kinks, Margit Valma, arhitektuuriteadlane Mait Väljas, Karisma Arhitektid), 2. koha pälvinud tööst "Õhuke Koht" (Pille Noole, Üllar Ambos, Kaisa Lasner, Kerttu Karjust, Jiannis Lykouras, Arhitektuurinurk), 3. koha pälvinud tööst "Tee" (Villem Tomiste, Stuudio Tallinn). Loetletud ostupreemia ja kolm tunnustuse pälvinud võistlustööd

  5. Trapped in the Carceral Net: Race, Gender, and the “War on Terror”

    Directory of Open Access Journals (Sweden)

    Yasmin Jiwani

    2011-01-01

    Full Text Available The events of September 11, 2001 unleashed a series of security measures designed ostensibly to protect Western nations from terrorist attacks. Many of these measures were aimed at keeping out potential terrorists and neutralizing potential terrorist activities. However, many were also aimed at citizens within the nation, legitimizing their exclusion and denial of rights. Drawing on the case of Omar Khadr, this paper argues that the carceral net ensnaring Omar Khadr was in operation well before 2001. However, since then, the carceral net has tightened to render Muslim bodies unworthy on the grounds of their putative criminality, and as undeserving victims, unbefitting state intervention and societal sympathy. The colour line, I argue, demarcates bodies that are considered worthy as opposed to those precarious others who can be penalized by the state and whose lives simply do not matter. Race, class and gender intersect and interlock to construct particular representations of victimhood as demonstrated by contemporary media representations of Muslim women.

  6. Compétences pour les PME de l'Amérique centrale dans l'économie ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Grâce à un projet de durée de 30 mois, deux établissements de recherche et de formation respectés dans la région (la Fundación Omar Dengo, du Costa Rica, et le Centro Interamericano para el Desarrollo del Conocimiento en la Formación Profesional (CINTERFOR) - un institut de recherche et de formation appuyé par ...

  7. The New Middle East Security Threat: The Case of Yemen and the GCC

    Science.gov (United States)

    2007-06-01

    time blasphemous: such practices as praying to the dead, making pilgrimages to mosques and tombs , using votives and making sacrifices to any one other...Sauds attacked Karbala and destroyed the Shi’ite shrine of the tomb of Caliph al-Husayn. In 1803, the Al Sauds captured Mecca and Medina. The...Oufi’s statement, an Egyptian expatriate, Omar Ahmad Abdullah Ali, set off a suicide bomb in the Doha Players Theatre. One Briton was killed and

  8. Modeling Red Blood Cell and Iron Dynamics in Patients with Chronic Kidney Disease

    Science.gov (United States)

    2012-02-10

    level in the body. Most patients with CKD have elevated levels of inflammation due to CKD and the presence of other medical issues (e.g., diabetes ...Blood, 37 (1971), 725–732. [11] Chung-Che Chang, Yayan Chen, Kapil Modi , Omar Awar, Clarence P. Alfrey, and Lawrence Rice, Changes of red blood cell...National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, 2008. [43] M. M. Udden, T. B. Driscoll, M

  9. Pulmonary hypertension and vasculopathy in incontinentia pigmenti: a case report

    OpenAIRE

    Alshenqiti, Abduljabbar; Nashabat, Marwan; AlGhoraibi, Hissah; Tamimi, Omar; Alfadhel, Majid

    2017-01-01

    Abduljabbar Alshenqiti,1 Marwan Nashabat,1 Hissah AlGhoraibi,1 Omar Tamimi,2 Majid Alfadhel1 1Division of Genetics, Department of Pediatrics, King Abdullah International Medical Research Centre, King Saud bin Abdulaziz Uiversity for Health Sciences, King Abdulaziz Medical City, Ministry of National Guard Health Affairs (NGHA), Riyadh, Saudi Arabia; 2Department of Cardiology, King Abdullah International Medical Research Centre, King Saud bin Abdulaziz University for Health Sciences, King Abdu...

  10. Guantanamo vangid pääsesid süüst / Heiki Suurkask

    Index Scriptorium Estoniae

    Suurkask, Heiki, 1972-

    2007-01-01

    USA sõjaväekohtunik Peter Brownback leidis, et kahe Guantanamo vangi, väidetavalt Osama bin Ladeni autojuhina tegutsenud Salim Ahmad Hamdani ning Kanada kodaniku Omar Khadri puhul ei võimalda seadused nende üle kohut mõista. Seni on Guantanamos viibinud vangidest vähemalt 340 süütuna või ohutuna vabaks lastud

  11. JPRS Report East Asia Southeast Asia

    Science.gov (United States)

    1987-06-29

    been a nuclear bomb. And such "accidents have hap- pened before, in Pa omares , Spain, and in Greenland, where thousands of acres were...IText] DAGWAYsa Inaway, , an exhibi- tion of new works by Bacolod- based Norberto Roldan , will be on view at Hiraya Gallery starting Tuesday...already depressed farming communities and rendered over 3,000 persons homeless. In the company of civic and medical aid missions, Roldan saw the

  12. Elevated Brain Cannabinoid CB1 Receptor Availability in Posttraumatic Stress Disorder: A Positron Emission Tomography Study

    Science.gov (United States)

    Neumeister, Alexander; Normandin, Marc D.; Pietrzak, Robert H.; Piomelli, Daniele; Zheng, Ming-Qiang; Gujarro-Anton, Ana; Potenza, Marc N.; Bailey, Christopher R.; Lin, Shu-fei; Najafzadeh, Soheila; Ropchan, Jim; Henry, Shannan; Corsi-Travali, Stefani; Carson, Richard E.; Huang, Yiyun

    2013-01-01

    Endocannabinoids and their attending cannabinoid type 1 receptor (CB1) have been implicated in animal models of posttraumatic stress disorder (PTSD). However, their specific role has not been studied in people with PTSD. Herein, we present an in vivo imaging study using positron emission tomography (PET) and the CB1-selective radioligand [11C]OMAR in individuals with PTSD, and healthy controls with lifetime histories of trauma (trauma controls [TC]) and those without such histories (healthy controls [HC]). Untreated individuals with PTSD (N=25) with non-combat trauma histories, and TC (N=12) and HC (N=23) participated in a magnetic resonance (MR) imaging scan and a resting PET scan with the CB1 receptor antagonist radiotracer [11C]OMAR, which measures volume of distribution (VT) linearly related to CB1 receptor availability. Peripheral levels of anandamide, 2-arachidonoylglycerol (2-AG), oleoylethanolamide (OEA), palmitoylethanolamide (PEA), and cortisol were also assessed. In the PTSD group, relative to the HC and TC groups, we found elevated brain-wide [11C]OMAR VT values (F(2,53)=7.96, p=.001; 19.5% and 14.5% higher, respectively) which were most pronounced in women (F(1,53)=5.52, p=.023). Anandamide concentrations were reduced in the PTSD relative to the TC (53.1% lower) and HC (58.2% lower) groups. Cortisol levels were lower in the PTSD and TC groups relative to the HC group. Three biomarkers examined collectively—OMAR VT, anandamide, and cortisol—correctly classified nearly 85% of PTSD cases. These results suggest that abnormal CB1 receptor-mediated anandamide signaling is implicated in the etiology of PTSD, and provide a promising neurobiological model to develop novel, evidence-based pharmacotherapies for this disorder. PMID:23670490

  13. Proceedings of the IDA (Institute for Defense Analyses) Workshop on Formal Specification and Verification of Ada (Trade Name) (2nd) Held in Alexandria, Virginia on July 23-25, 1985.

    Science.gov (United States)

    1985-11-01

    2% -N X Mailing Directory U Bernard Abrams ABRAMS@USC-ECLB Grumman Aerospace Corporation Mail Station 001-31T Bethpage, NY 11714 (516) 575-9487 Omar...Aerospace & Comm. Corp. 10440 State Highway 83 Colorado Springs, Colorado 80908 Mark R. Cornwell CORNWELL @NRL-CSS Code 7590 Naval Research Lab Washington...5) Role of the Formal Definition of Ada Bernard Lang, INRIA, no date, 10 pages [6) The Users of a Formal Definition for Ada Bernd Krieg-Brdckner 2

  14. The Critical Role of Positive Incentives for Reducing Insider Threats

    Science.gov (United States)

    2016-12-01

    such skills . Creating a technical track of advancement separate from the management track can help ameliorate these problems. Effective Communication ...Omar, F.; Halim, F. W.; & Hafidz, S. W. M. The Mediating Role of Organizational- Based Self - Esteem in Perceived Organizational Support and... Esteem Relate to Deviant Behavior? The Role of Contingencies of Self -Worth. Journal of Applied Psychology. Volume 94. Number 5. September 2009. Page

  15. Vigour Health: the ASC-Series launch in Canada

    OpenAIRE

    Danielsen, David M.; Fredriksen, Joakim; Nordli, Espen; Nøstberg, Bjørn R.

    2008-01-01

    This report is part of the authors’ bachelor degree in International Marketing and analyzes the Canadian vitamins and dietary supplements (VDS) industry. Based on this analysis, the authors will be proposing how Vigour can enter the market. Vigour Health was founded in 2006 by Omar Paulsen Bekheet and John Ivar Andre and the goal was to introduce a new lifestyle concept that should be inventive in its approach. Vigour utilizes raw materials from the northern parts of Norway, an...

  16. The Nature of Insurgency in Afghanistan and the Regional Power Politics

    Science.gov (United States)

    2010-06-01

    www.thebulletin.org/web- edition/ columnists /gordon-adams/afghanistan-and-pakistan-the-graveyard-us-foreign-policy-plannin (accessed January 20, 2010). 84 Anotnio...comprising an “insurgent syndicate .”152 This syndicate includes the Afghan Taliban under Mullah Muhammad Omar, who is allegedly operating from... syndicate , Hizb-i-Islami (HiG), is another old Afghan Mujahedeen organization led by Gulbuddin Hekmatyar. HiG received maximum support from the CIA

  17. Sonomammographic characteristics of invasive lobular carcinoma

    OpenAIRE

    Fahmy, Dalia Monir; Kombar,; Farouk,Omar; El-damshety,; Brown,

    2012-01-01

    Osama R Kombar,1,3 Dalia M Fahmy,1 Mary V Brown,3 Omar Farouk,2 Osama El-Damshety21Diagnostic Radiology Department, 2Surgical Oncology Department, Oncology Center, Mansoura University, Mansoura, Egypt; 3Diagnostic Radiology Department, Al-Amiri Hospital, Safat, KuwaitObjective: The objective of our study was to identify characteristic features of invasive lobular carcinoma on mammography and ultrasound examinationsMaterials and methods: This is a retrospective multicenter study of women with ...

  18. Hacking Facebook Privacy and Security

    Science.gov (United States)

    2012-08-28

    REPORT Hacking Facebook Privacy and Security 14. ABSTRACT 16. SECURITY CLASSIFICATION OF: When people talk about hacking and social networks , they’re...12211 Research Triangle Park, NC 27709-2211 15. SUBJECT TERMS Facebook , Privacy, Security, Social Network Dr. Jeff Duffany (Advisor), Omar Galban...transmit personal information that many people that they dare not do it personally. FACEBOOK PLATFORM Facebook is a popular social networking

  19. SU-F-T-441: Dose Calculation Accuracy in CT Images Reconstructed with Artifact Reduction Algorithm

    Energy Technology Data Exchange (ETDEWEB)

    Ng, C; Chan, S; Lee, F; Ngan, R [Queen Elizabeth Hospital (Hong Kong); Lee, V [University of Hong Kong, Hong Kong, HK (Hong Kong)

    2016-06-15

    Purpose: Accuracy of radiotherapy dose calculation in patients with surgical implants is complicated by two factors. First is the accuracy of CT number, second is the dose calculation accuracy. We compared measured dose with dose calculated on CT images reconstructed with FBP and an artifact reduction algorithm (OMAR, Philips) for a phantom with high density inserts. Dose calculation were done with Varian AAA and AcurosXB. Methods: A phantom was constructed with solid water in which 2 titanium or stainless steel rods could be inserted. The phantom was scanned with the Philips Brillance Big Bore CT. Image reconstruction was done with FBP and OMAR. Two 6 MV single field photon plans were constructed for each phantom. Radiochromic films were placed at different locations to measure the dose deposited. One plan has normal incidence on the titanium/steel rods. In the second plan, the beam is at almost glancing incidence on the metal rods. Measurements were then compared with dose calculated with AAA and AcurosXB. Results: The use of OMAR images slightly improved the dose calculation accuracy. The agreement between measured and calculated dose was best with AXB and image reconstructed with OMAR. Dose calculated on titanium phantom has better agreement with measurement. Large discrepancies were seen at points directly above and below the high density inserts. Both AAA and AXB underestimated the dose directly above the metal surface, while overestimated the dose below the metal surface. Doses measured downstream of metal were all within 3% of calculated values. Conclusion: When doing treatment planning for patients with metal implants, care must be taken to acquire correct CT images to improve dose calculation accuracy. Moreover, great discrepancies in measured and calculated dose were observed at metal/tissue interface. Care must be taken in estimating the dose in critical structures that come into contact with metals.

  20. Applying theory of planned behavior to predict exercise maintenance in sarcopenic elderly

    OpenAIRE

    Ahmad MH; Shahar S; Teng NIMF; Manaf ZA; Sakian NIM; Omar B

    2014-01-01

    Mohamad Hasnan Ahmad,1 Suzana Shahar,2 Nur Islami Mohd Fahmi Teng,2 Zahara Abdul Manaf,2 Noor Ibrahim Mohd Sakian,3 Baharudin Omar41Centre of Nutrition Epidemiology Research, Institute of Public Health, Ministry of Health, Kuala Lumpur, Malaysia; 2Dietetics Program, 3Occupational Therapy Program, 4Department of Biomedical Sciences, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia Abstract: This study aimed to determine the factors associated with exercise beh...

  1. Puuskulptuurid tagasi Pärnus / Tiiu Leis

    Index Scriptorium Estoniae

    Leis, Tiiu

    1998-01-01

    'Puu 98' raames Kõpu külas valminud 3 puuskulptuuri: Toomas Mitti (Tõstamaa kooli direktor) 'Ahel', Omar Tamme 'Pähklipureja' ja Pjotr Romanjuki 'Maailma neli vaadet' jõuavad Rocca al Marest tagasi Pärnusse, kus neid eksponeeritakse paar nädalat hotelli 'Victoria' ees ning antakse seejärel üle Pärnu maavalitsusele ja 'Puu 98' toetajatele

  2. CTC Sentinel. Volume 4, Issue 4, April 2011

    Science.gov (United States)

    2011-04-01

    Online, April 28, 2010. 3 Personal interview, Khalid Khwaja, March 2010. 4 Personal interview, Usman Punjabi , Winter 2010. 5 Hamid Mir, “What Was...members’ identities. It eventually emerged that the Punjabi Taliban—jihadists who left Kashmir-focused militant groups and joined the TTP—were...involved in the kidnapping operation. Usman Punjabi , or Mohammad Omar as he identified himself when contacting the media, became the link between

  3. Le CRDI au Costa Rica

    International Development Research Centre (IDRC) Digital Library (Canada)

    région ont-elles besoin du commerce, mais elles doivent en outre acquérir de nouvelles compétences afin de pouvoir prospérer dans l'économie du savoir. La capacité d'utiliser les technologies de l'information, entre autres, est désormais une nécessité. Le CRDI subventionne la Fundación. Omar Dengo afin qu'elle puisse ...

  4. Fighting the Big War with the Small Hammer: Operational Planning for the Medium Force

    Science.gov (United States)

    2015-05-23

    2008), 26. 27 Christopher F. Foss, eds., Jane’s: Armour and Artillery 2004-2005 (Alexandria, VA: Jane’s Information Group, 2004), 159, 409, and 553...WA: Headquarters 9th Infantry Division, 1989. Bradley, Omar N. A Soldier’s Story. New York, NY: Henry Holt and Company Inc , 1951. Brown, John S...Foss, Christopher F., eds. Jane’s: Armour and Artillery 2004-2005. Alexandria, VA: Jane’s Information Group, 2004. Fubini, Eugene G. Task Force on

  5. Planning and clinical studies of a commercial orthopedic metal artifact reduction tool for CT simulations for head-and-neck radiotherapy

    International Nuclear Information System (INIS)

    Kon, Hyuck Jun; Ye, Sung Joon; Kim, Jung In; Park, Jong Min; Lee, Jae Gi; Heo, Tae Min; Kim Kyung Su; Chun, Young Mi; Callahan, Zachariah

    2013-01-01

    In computed tomography (CT) images, the presence of high Z materials induces typical streak artifacts, called metal artifacts which can pervert CT Hounsfield numbers in the reconstructed images. These artifact-induced distortion of CT images can impact on the dose calculation based on the CT images. In the radiation therapy of Head-and-Neck cancer because of the concave-shaped target volumes, the complex anatomy, a lot of sensitive normal tissues and air cavity structures, it is important to get accurate CT images for dose calculation. But dental implant is common for H and N patients so that it is hard to get undistorted CT images. Moreover because dental implants are generally with the air cavity like oral cavity and nasal cavity in the same CT slice, they can make lots of distortion. In this study, we focused on evaluating the distortion on air cavity by the metal artifact and the effectiveness of the commercial orthopedic metal artifact reduction function (O-MAR) about the metal artifacts induced by the dental implant. The O-MAR algorithm increases the accuracy of CT Hounsfield numbers and reducing noises. Thus, it can contribute to the entire radiation treatment planning process, especially for contouring/segmentation. Although there was no significant difference in dose distributions for most cases, the O-MAR correction was shown to have an impact on high dose regions in air cavity

  6. Computed Tomography Imaging of a Hip Prosthesis Using Iterative Model-Based Reconstruction and Orthopaedic Metal Artefact Reduction: A Quantitative Analysis.

    Science.gov (United States)

    Wellenberg, Ruud H H; Boomsma, Martijn F; van Osch, Jochen A C; Vlassenbroek, Alain; Milles, Julien; Edens, Mireille A; Streekstra, Geert J; Slump, Cornelis H; Maas, Mario

    To quantify the combined use of iterative model-based reconstruction (IMR) and orthopaedic metal artefact reduction (O-MAR) in reducing metal artefacts and improving image quality in a total hip arthroplasty phantom. Scans acquired at several dose levels and kVps were reconstructed with filtered back-projection (FBP), iterative reconstruction (iDose) and IMR, with and without O-MAR. Computed tomography (CT) numbers, noise levels, signal-to-noise-ratios and contrast-to-noise-ratios were analysed. Iterative model-based reconstruction results in overall improved image quality compared to iDose and FBP (P < 0.001). Orthopaedic metal artefact reduction is most effective in reducing severe metal artefacts improving CT number accuracy by 50%, 60%, and 63% (P < 0.05) and reducing noise by 1%, 62%, and 85% (P < 0.001) whereas improving signal-to-noise-ratios by 27%, 47%, and 46% (P < 0.001) and contrast-to-noise-ratios by 16%, 25%, and 19% (P < 0.001) with FBP, iDose, and IMR, respectively. The combined use of IMR and O-MAR strongly improves overall image quality and strongly reduces metal artefacts in the CT imaging of a total hip arthroplasty phantom.

  7. A review on organic spintronic materials and devices: I. Magnetic field effect on organic light emitting diodes

    Directory of Open Access Journals (Sweden)

    Rugang Geng

    2016-06-01

    Full Text Available Organic spintronics is an emerging and potential platform for future electronics and display due to the intriguing properties of organic semiconductors (OSCs. For the past decade, studies have focused on three types of organic spintronic phenomena: (i magnetic field effect (MFE in organic light emitting diodes (OLEDs, where spin mixing between singlet and triplet polaron pairs (PP can be influenced by an external magnetic field leading to organic magnetoresistive effect (OMAR; (ii magnetoresistance (MR in organic spin valves (OSVs, where spin injection, transport, manipulation, and detection have been demonstrated; and (iii magnetoelectroluminescence (MEL bipolar OSVs or spin-OLEDs, where spin polarized electrons and holes are simultaneously injected into the OSC layer, leading to the dependence of electroluminescence intensity on relative magnetization of the electrodes. In this first of two review papers, we present major experimental results on OMAR studies and current understanding of OMAR using several spin dependent processes in organic semiconductors. During the discussion, we highlight some of the outstanding challenges in this promising research field. Finally, we provide an outlook on the future of organic spintronics.

  8. Planning and clinical studies of a commercial orthopedic metal artifact reduction tool for CT simulations for head-and-neck radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Kon, Hyuck Jun; Ye, Sung Joon [Interdisplinary Program in Radiation Applied Life Science, Seoul National University Graduate School, Seoul (Korea, Republic of); Kim, Jung In; Park, Jong Min; Lee, Jae Gi; Heo, Tae Min [Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul (Korea, Republic of); Kim Kyung Su [Dept. of Radiation Oncology, Seoul National University College of Medicine, Seoul (Korea, Republic of); Chun, Young Mi [Philips Healthcare Korea, Seoul (Korea, Republic of); Callahan, Zachariah [Program in Biomedical Radiation Sciences, Dept. of Transdisciplinary Studies, Graduate School of Convergence Science and Technology, Seoul National University, Seoul (Korea, Republic of)

    2013-11-15

    In computed tomography (CT) images, the presence of high Z materials induces typical streak artifacts, called metal artifacts which can pervert CT Hounsfield numbers in the reconstructed images. These artifact-induced distortion of CT images can impact on the dose calculation based on the CT images. In the radiation therapy of Head-and-Neck cancer because of the concave-shaped target volumes, the complex anatomy, a lot of sensitive normal tissues and air cavity structures, it is important to get accurate CT images for dose calculation. But dental implant is common for H and N patients so that it is hard to get undistorted CT images. Moreover because dental implants are generally with the air cavity like oral cavity and nasal cavity in the same CT slice, they can make lots of distortion. In this study, we focused on evaluating the distortion on air cavity by the metal artifact and the effectiveness of the commercial orthopedic metal artifact reduction function (O-MAR) about the metal artifacts induced by the dental implant. The O-MAR algorithm increases the accuracy of CT Hounsfield numbers and reducing noises. Thus, it can contribute to the entire radiation treatment planning process, especially for contouring/segmentation. Although there was no significant difference in dose distributions for most cases, the O-MAR correction was shown to have an impact on high dose regions in air cavity.

  9. Human Parvoviruses

    Science.gov (United States)

    Söderlund-Venermo, Maria; Young, Neal S.

    2016-01-01

    SUMMARY Parvovirus B19 (B19V) and human bocavirus 1 (HBoV1), members of the large Parvoviridae family, are human pathogens responsible for a variety of diseases. For B19V in particular, host features determine disease manifestations. These viruses are prevalent worldwide and are culturable in vitro, and serological and molecular assays are available but require careful interpretation of results. Additional human parvoviruses, including HBoV2 to -4, human parvovirus 4 (PARV4), and human bufavirus (BuV) are also reviewed. The full spectrum of parvovirus disease in humans has yet to be established. Candidate recombinant B19V vaccines have been developed but may not be commercially feasible. We review relevant features of the molecular and cellular biology of these viruses, and the human immune response that they elicit, which have allowed a deep understanding of pathophysiology. PMID:27806994

  10. Structure and dynamics of interfacial water. Role of hydratation water in the globular proteins dynamics; Structure et dynamique de l`eau interfaciale. Role de l`eau d`hydratation dans la dynamique des proteines globulaires

    Energy Technology Data Exchange (ETDEWEB)

    Zanotti, J.M.

    1997-01-27

    This memoir includes five chapters. In the first chapter, are given the elements of the neutrons scattering theory that is used in this study. the second chapter is devoted to a general presentation of the interaction between biological macro molecule and water. The third part is dedicated to the study of the structure and the dynamics of interfacial water in the neighbouring of model systems, the vycor and the amorphous carbon. The results presented in this part are compared with these one relative to water dynamics at the C-phycocyanin surface. This study makes the object of the fourth chapter. Then, in the fifth and last chapter are discussed the results relative to the role of hydratation on the parv-albumin dynamics for which have been combined the neutron quasi elastic incoherent scattering and the nuclear magnetic resonance of the carbon 13 solid in natural abundance.

  11. Structure and dynamics of interfacial water. Role of hydratation water in the globular proteins dynamics

    International Nuclear Information System (INIS)

    Zanotti, J.M.

    1997-01-01

    This memoir includes five chapters. In the first chapter, are given the elements of the neutrons scattering theory that is used in this study. the second chapter is devoted to a general presentation of the interaction between biological macro molecule and water. The third part is dedicated to the study of the structure and the dynamics of interfacial water in the neighbouring of model systems, the vycor and the amorphous carbon. The results presented in this part are compared with these one relative to water dynamics at the C-phycocyanin surface. This study makes the object of the fourth chapter. Then, in the fifth and last chapter are discussed the results relative to the role of hydratation on the parv-albumin dynamics for which have been combined the neutron quasi elastic incoherent scattering and the nuclear magnetic resonance of the carbon 13 solid in natural abundance

  12. "Kus sa oled mu võluratsu..." : [luuletused] / Mõkola Vingranovski ; tlk. Harald Rajamets

    Index Scriptorium Estoniae

    Vingranovski, Mõkola

    2004-01-01

    Sisu: "Kus sa oled mu võluratsu..." ; Ja rahvas on... ; "Oled rada, mu armsam..." ; "Sa oled siin! Mu armastus, mu lumm..." ; "Me ahvatluste aastad, albid aastad..." ; "Mul juba siis, kui oli kevad veel..." ; "Nüüd tõuse, kalur! Kustumas on tähed..." ; Meresügisel ; "Kauss hirsiputru, õilmelend..." ; "Õde võõpab aias õunapuid..." ; Esimene hälilaul ; "Noor tüdruk, alles laps. Ei kõnni kikivarvul..." ; "Ülal künka peal seisis päike..." ; "Jäid suve lõpul tuhmiks puud..." ; "Nüüd hakkab lumesadu, nüüd..." ; "Lumehämarus, hall nagu hall..." ; "Tüüpõllu aur on jäärakute kohal..." ; "Parv linde kriiskab salu kohal..." ; "Põld kuivi maisivarsi täis..." ; Haiavata

  13. Hardwiring of fine synaptic layers in the zebrafish visual pathway

    Directory of Open Access Journals (Sweden)

    Taylor Michael R

    2008-12-01

    Full Text Available Abstract Background Neuronal connections are often arranged in layers, which are divided into sublaminae harboring synapses with similar response properties. It is still debated how fine-grained synaptic layering is established during development. Here we investigated two stratified areas of the zebrafish visual pathway, the inner plexiform layer (IPL of the retina and the neuropil of the optic tectum, and determined if activity is required for their organization. Results The IPL of 5-day-old zebrafish larvae is composed of at least nine sublaminae, comprising the connections between different types of amacrine, bipolar, and ganglion cells (ACs, BCs, GCs. These sublaminae were distinguished by their expression of cell type-specific transgenic fluorescent reporters and immunohistochemical markers, including protein kinase Cβ (PKC, parvalbumin (Parv, zrf3, and choline acetyltransferase (ChAT. In the tectum, four retinal input layers abut a laminated array of neurites of tectal cells, which differentially express PKC and Parv. We investigated whether these patterns were affected by experimental disruptions of retinal activity in developing fish. Neither elimination of light inputs by dark rearing, nor a D, L-amino-phosphono-butyrate-induced reduction in the retinal response to light onset (but not offset altered IPL or tectal lamination. Moreover, thorough elimination of chemical synaptic transmission with Botulinum toxin B left laminar synaptic arrays intact. Conclusion Our results call into question a role for activity-dependent mechanisms – instructive light signals, balanced on and off BC activity, Hebbian plasticity, or a permissive role for synaptic transmission – in the synaptic stratification we examined. We propose that genetically encoded cues are sufficient to target groups of neurites to synaptic layers in this vertebrate visual system.

  14. Examenes pulmonares por el método de Abreu: sus resultados

    Directory of Open Access Journals (Sweden)

    Alfonso Reyes

    1950-02-01

    definitiva en 1936. Posteriormente el doctor Hanker aplica la Abrengrafía al examen en serio de colectividades. Entre nosotros, fue el doctor Omar Benavides en 1940 quien presentó su trabajo de tesis sobre las primeras abreugrafías tomadas en un aparato ideado por él. En Bogotá, se inició la campaña por este sistema en enero de 1947 con la fundación del Centro Epidemiológico No 1, dirigido por el doctor Antonio Acosta Pinzón.

  15. Cerebro y metáfora en la novela "Pedro Páramo", de Juan Rulfo

    Directory of Open Access Journals (Sweden)

    CECILIA EDILMA DÍAZ DÍAZ

    2010-01-01

    Full Text Available Se trata de un avance de investigación que aplica la teoría neurolingüística de Omar Parra Rozo para leer y comprender la metáfora en un texto literario. Se toma como objeto de estudio la novela "Pedro Páramo" de Juan Rulfo, específicamente los fragmentos que hablan acerca de la imagen compleja (religión-poder y muerte. El ejercicio de investigación alcanzó a establecer la relación que existe entre imagen- cerebro y metáfora, en el discurso de esta novela.

  16. Between Scylla and Charybdis: Constructing the Nicaraguan Army

    Science.gov (United States)

    2009-02-18

    Politicos En Uniforme: Un Balance del Poder del EPS (Managua: Instituto Nicaragüense de Estudios Socio-Politicos, 1992), 19. 37 Republic of Nicaragua...Democracia, 205. 39 Guzmán, Politicos En Uniforme: Un Balance del Poder del EPS, 123. 40 General Moisés Omar Halleslevens Acevedo, Commander of the...June 10 & 17, 2008. 62 Guzmán, Politicos En Uniforme: Un Balance del Poder del EPS, 64. 63 The United States Department of State, “Country Background

  17. Incidencia del conflicto armado de Darfur en las relaciones políticas entre Sudán y Chad durante el período 2005-2009.

    OpenAIRE

    España Feria, Olga Patricia

    2012-01-01

    Las relaciones políticas entre Sudán y Chad en el período 2005-2009 se vieron afectadas por el conflicto armado de Darfur, que trajo consigo consecuencias graves para ambos países. La configuración étnica similar, los antecedentes históricos que muestran fuertes vínculos entre Sudán y Chad y las continuas acusaciones entre Omar Al-Bashir e Idriss Déby, hicieron que las tensiones entre los dos gobiernos llamaran la atención de la comunidad internacional y causara preocupación por una posible d...

  18. Low-dose CT imaging of a total hip arthroplasty phantom using model-based iterative reconstruction and orthopedic metal artifact reduction

    Energy Technology Data Exchange (ETDEWEB)

    Wellenberg, R.H.H.; Streekstra, G.J.; Maas, M. [Academic Medical Center, Department of Radiology, Amsterdam (Netherlands); Boomsma, M.F.; Osch, J.A.C. van [Department of Radiology, Zwolle (Netherlands); Vlassenbroek, A. [Philips Medical Systems, Brussels (Belgium); Milles, J. [Philips Medical Systems, Eindhoven (Netherlands); Edens, M.A. [Department of Innovation and Science, Zwolle (Netherlands); Slump, C.H. [University of Twente, MIRA Institute for Biomedical Technology and Technical Medicine, Enschede (Netherlands)

    2017-05-15

    To compare quantitative measures of image quality, in terms of CT number accuracy, noise, signal-to-noise-ratios (SNRs), and contrast-to-noise ratios (CNRs), at different dose levels with filtered-back-projection (FBP), iterative reconstruction (IR), and model-based iterative reconstruction (MBIR) alone and in combination with orthopedic metal artifact reduction (O-MAR) in a total hip arthroplasty (THA) phantom. Scans were acquired from high- to low-dose (CTDI{sub vol}: 40.0, 32.0, 24.0, 16.0, 8.0, and 4.0 mGy) at 120- and 140- kVp. Images were reconstructed using FBP, IR (iDose{sup 4} level 2, 4, and 6) and MBIR (IMR, level 1, 2, and 3) with and without O-MAR. CT number accuracy in Hounsfield Units (HU), noise or standard deviation, SNRs, and CNRs were analyzed. The IMR technique showed lower noise levels (p < 0.01), higher SNRs (p < 0.001) and CNRs (p < 0.001) compared with FBP and iDose{sup 4} in all acquisitions from high- to low-dose with constant CT numbers. O-MAR reduced noise (p < 0.01) and improved SNRs (p < 0.01) and CNRs (p < 0.001) while improving CT number accuracy only at a low dose. At the low dose of 4.0 mGy, IMR level 1, 2, and 3 showed 83%, 89%, and 95% lower noise values, a factor 6.0, 9.2, and 17.9 higher SNRs, and 5.7, 8.8, and 18.2 higher CNRs compared with FBP respectively. Based on quantitative analysis of CT number accuracy, noise values, SNRs, and CNRs, we conclude that the combined use of IMR and O-MAR enables a reduction in radiation dose of 83% compared with FBP and iDose{sup 4} in the CT imaging of a THA phantom. (orig.)

  19. Réplica al artículo Periodismo mutante y bastardo

    Directory of Open Access Journals (Sweden)

    Pedro Vázquez-Miraz

    2018-01-01

    Full Text Available Se presenta en el siguiente texto una réplica del artículo ensayístico “Periodismo mutante y bastardo” del Dr. Omar Rincón, en el que se analiza esta propuesta de flamante periodismo que ha presentado el autor. Consideramos el periodismo mutante y bastardo como una opción redundante que no aporta nueva información y presenta notables incongruencias entre el viejo modelo periodístico que se critica en el documento y esta nueva propuesta.

  20. Plan Colombia: How U.S. Military Assistance Affects Regional Balances of Powers

    Science.gov (United States)

    2004-06-01

    Kenneth Waltz, Theory of International Politics, (1979), p. 118. 27 Hans Morgenthau, Política Entre Las Naciones: La Lucha por el Poder y a Paz. Grupo ...Incidente del Caldas Manejo de una Crisis Política”, Unpublished Thesis. Universidad Simón Bolívar, (1995). p. 1. Translated by Omar Pina. 30 1...1987). p. 56. 70 Soto, J. “El Incidente del Caldas Manejo de una Crisis Política.” Unpublished Thesis. Caracas: Universidad Simón Bolívar(1995), p

  1. Bagatellid : maailm / Nele-Eva Steinfeld, Ivo Heinloo

    Index Scriptorium Estoniae

    Steinfeld, Nele-Eva

    2011-01-01

    Muusikasõnumeid maailmast: 14. Tšaikovski nimelisest konkursist. Daniel Barenboim tõstetakse rüütliseisusesse. Orkestrist I, Culture Orchestra. Charles Dutoit plaanib luua Lõuna- ja Põhja-Koread ühendava orkestri. Lahkus Josef Suk. Seiji Ozawa pälvis Praemium Imperiale auhinna. Cardiffi lauljate konkursi võitis Valentina Nafornita. Lahkus Nikolai Petrov. Venetsueelas lööb laineid noor dirigent Jose Omar Davila. "Jazzkaare" täht Brass Jaw sai Suurbritannias suure tunnustuse osaliseks. Põhjamaade Nõukogu muusikaauhinna teenis Mats Gustafsson. Black Eyed Peas paneb pillid kotti. Kuuba kitarrist Manuel Galban surnud. Eesti on Tšehhi jazziraadio fookuses

  2. Future perspectives and their relation to wellbeing and resilience in adolescents

    Directory of Open Access Journals (Sweden)

    Alicia Omar

    2015-09-01

    Full Text Available Previous research (Omar, 2005; Omar, Uribe Delgado & Maltaneres, 2005, had showed a clear relationship between subjective well-being and resilience. In those opportunities, however, resilience was considered as a global construct. This study aims at exploring the possible relationships among resilience components, subjective well-being, and future perspectives. Method: Sample integrated by 198 (105 girls & 93 boys Argentinean high school students, 14- to 19-yr.-old. All sample participants answered a booklet that included Wagnild and Young’s Resilience Scale (1993; Nagpal and Sell’s Subjective Well-being Scale (1992, and three items specially developed to explore academic, labor, and family future perspectives. Development: correlation analysis indicated positive significant associations between resilience’s components (Personal realization; Self- determination, and Adaptation, and specific well-being dimensions. Likewise, resilience’s components and subjective well being dimensions showed significant correlations with positive future perspectives. No gender-specific differences were observed in any of the variables under analysis. Results: findings showed that adolescent resilience would be associated to familiar emotional support and positive social interchanges. Future orientations could be considered a new resilience protective factor. Social, familiar, and educational implications of these finding are discussed. A research agenda designed to further our understanding of resilience, well-being, and future perspectives linkages is proposed. 

  3. Semidarkness in the sport insertion in the national artistic daily life

    Directory of Open Access Journals (Sweden)

    Rafael A. Bernal-Castellanos

    2013-04-01

    Full Text Available No major technical or sufficient disclosure deployments, the extent of not being officially seen even in some provinces, in the halls of Cuban film was shown at the end of 2012, the production Penumbras, a co-production of RTC Commercial and Cuban TV with collaboration INDER and the ICAIC. The work, under the direction of Charlie Medina and performances by Omar Franco, Thomas Cao, Ismercy Solomon and Omar Ali, is based on a play by Amado del Pino entitled Penumbras in the ninth quarter on which the writer Carlos D. Lechuga he developed his work. Except meción to the above data INDER nothing it warns that might suggest the presence in it of elements of physical culture, let alone baseball; however the tape is one of the most significant works where the link between sport and national culture through its incidence is appreciated in everyday life of ordinary people, although it can not be said of their quality as a finished cosmetic product.

  4. An evaluation of three commercially available metal artifact reduction methods for CT imaging

    International Nuclear Information System (INIS)

    Huang, Jessie Y; Kerns, James R; Balter, Peter A; Followill, David S; Mirkovic, Dragan; Howell, Rebecca M; Kry, Stephen F; Nute, Jessica L; Liu, Xinming; Stingo, Francesco C

    2015-01-01

    Three commercial metal artifact reduction methods were evaluated for use in computed tomography (CT) imaging in the presence of clinically realistic metal implants: Philips O-MAR, GE’s monochromatic gemstone spectral imaging (GSI) using dual-energy CT, and GSI monochromatic imaging with metal artifact reduction software applied (MARs). Each method was evaluated according to CT number accuracy, metal size accuracy, and streak artifact severity reduction by using several phantoms, including three anthropomorphic phantoms containing metal implants (hip prosthesis, dental fillings and spinal fixation rods). All three methods showed varying degrees of success for the hip prosthesis and spinal fixation rod cases, while none were particularly beneficial for dental artifacts. Limitations of the methods were also observed. MARs underestimated the size of metal implants and introduced new artifacts in imaging planes beyond the metal implant when applied to dental artifacts, and both the O-MAR and MARs algorithms induced artifacts for spinal fixation rods in a thoracic phantom. Our findings suggest that all three artifact mitigation methods may benefit patients with metal implants, though they should be used with caution in certain scenarios. (paper)

  5. AR-V7 in Peripheral Whole Blood of Patients with Castration-resistant Prostate Cancer: Association with Treatment-specific Outcome Under Abiraterone and Enzalutamide.

    Science.gov (United States)

    Seitz, Anna Katharina; Thoene, Silvia; Bietenbeck, Andreas; Nawroth, Roman; Tauber, Robert; Thalgott, Mark; Schmid, Sebastian; Secci, Ramona; Retz, Margitta; Gschwend, Jürgen E; Ruland, Jürgen; Winter, Christof; Heck, Matthias M

    2017-11-01

    It has been demonstrated that androgen receptor splice variant 7 (AR-V7) expression in circulating tumor cells (CTCs) predicts poor treatment response in metastatic castration-resistant prostate cancer (mCRPC) patients treated with abiraterone or enzalutamide. To develop a practical and robust liquid profiling approach for direct quantification of AR-V7 in peripheral whole blood without the need for CTC capture and to determine its potential for predicting treatment response in mCRPC patients. Whole blood samples from a prospective biorepository of 85 mCRPC patients before treatment initiation with abiraterone (n=56) or enzalutamide (n=29) were analyzed via droplet digital polymerase chain reaction. The association of AR-V7 status with prostate-specific antigen (PSA) response defined by PSA decline ≥50% and with PSA-progression-free survival (PSA-PFS), clinical PFS, and overall survival (OS) was assessed. High AR-V7 expression levels in whole blood were detectable in 18% (15/85) of patients. No patient with high AR-V7 expression achieved a PSA response, and AR-V7 status was an independent predictor of PSA response in multivariable logistic regression analysis (p=0.03). High AR-V7 expression was associated with shorter PSA-PFS (median 2.4 vs 3.7 mo; pAR-V7 expression remained an independent predictor of shorter PSA-PFS (hazard ratio [HR] 7.0, 95% confidence interval [CI] 2.3-20.7; pAR-V7 mRNA levels in whole blood is a simple and promising approach to predict poor treatment outcome in mCRPC patients receiving abiraterone or enzalutamide. We established a method for determining AR-V7 status in whole blood. This test predicted treatment resistance in patients with metastatic castration-resistant prostate cancer undergoing treatment with abiraterone or enzalutamide. Prospective validation is needed before application to clinical practice. Copyright © 2017 European Association of Urology. Published by Elsevier B.V. All rights reserved.

  6. Electron transfer driven decomposition of adenine and selected analogs as probed by experimental and theoretical methods

    Science.gov (United States)

    Cunha, T.; Mendes, M.; Ferreira da Silva, F.; Eden, S.; García, G.; Bacchus-Montabonel, M.-C.; Limão-Vieira, P.

    2018-04-01

    We report on a combined experimental and theoretical study of electron-transfer-induced decomposition of adenine (Ad) and a selection of analog molecules in collisions with potassium (K) atoms. Time-of-flight negative ion mass spectra have been obtained in a wide collision energy range (6-68 eV in the centre-of-mass frame), providing a comprehensive investigation of the fragmentation patterns of purine (Pu), adenine (Ad), 9-methyl adenine (9-mAd), 6-dimethyl adenine (6-dimAd), and 2-D adenine (2-DAd). Following our recent communication about selective hydrogen loss from the transient negative ions (TNIs) produced in these collisions [T. Cunha et al., J. Chem. Phys. 148, 021101 (2018)], this work focuses on the production of smaller fragment anions. In the low-energy part of the present range, several dissociation channels that are accessible in free electron attachment experiments are absent from the present mass spectra, notably NH2 loss from adenine and 9-methyl adenine. This can be understood in terms of a relatively long transit time of the K+ cation in the vicinity of the TNI tending to enhance the likelihood of intramolecular electron transfer. In this case, the excess energy can be redistributed through the available degrees of freedom inhibiting fragmentation pathways. Ab initio theoretical calculations were performed for 9-methyl adenine (9-mAd) and adenine (Ad) in the presence of a potassium atom and provided a strong basis for the assignment of the lowest unoccupied molecular orbitals accessed in the collision process.

  7. Auditory cortical processing in real-world listening: the auditory system going real.

    Science.gov (United States)

    Nelken, Israel; Bizley, Jennifer; Shamma, Shihab A; Wang, Xiaoqin

    2014-11-12

    The auditory sense of humans transforms intrinsically senseless pressure waveforms into spectacularly rich perceptual phenomena: the music of Bach or the Beatles, the poetry of Li Bai or Omar Khayyam, or more prosaically the sense of the world filled with objects emitting sounds that is so important for those of us lucky enough to have hearing. Whereas the early representations of sounds in the auditory system are based on their physical structure, higher auditory centers are thought to represent sounds in terms of their perceptual attributes. In this symposium, we will illustrate the current research into this process, using four case studies. We will illustrate how the spectral and temporal properties of sounds are used to bind together, segregate, categorize, and interpret sound patterns on their way to acquire meaning, with important lessons to other sensory systems as well. Copyright © 2014 the authors 0270-6474/14/3415135-04$15.00/0.

  8. Upper Cenozoic deposits of the central Delmarva Peninsula, Maryland and Delaware

    Science.gov (United States)

    Owens, James Patrick; Denny, Charles Storrow

    1979-01-01

    The surface and shallow subsurface sediments of the lower Delmarva Peninsula include beds ranging in age from Miocene to Holocene. The oldest beds appear to be typical shelf deposits of the Chesapeake Group (Calvert-Choptank age). These marine units are overlain by deltaic deposits, which range from fluviatile facies in the north (Pensauken Formation) to marginal marine and marine beds in the south ('Yorktown(?) and Cohansey(?)' Formations as used by Rasmussen and Slaughter in 1955). This large deltaic mass underlies most of the Delmarva Peninsula. Fossil age determinations supplemented by some radiometric dates indicate the delta to be largely late Miocene in age. The nonmarine facies of the delta, the Pensauken Formation, previously was considered to be Pleistocene in age. The late Miocene delta and possibly the Yorktown Formation (lower to middle Pliocene) are overlain by a feldspathic sand, the Beaverdam, which is at least in part marginal marine. Microflora recovered from this formation include species no longer indigenous to the Delmarva region ('exotics'). On the basis of existing information, microfloral assemblages containing 'exotics' are pre-Pleistocene in age. The Beaverdam therefore is pre-Pleistocene in age, probably late Pliocene. A highly dissected and weathered unit, the Walston Silt, caps the uplands of the central Delmarva Peninsula, where it overlies the Beaverdam. The Walston has a microflora containing 'exotics' and therefore is considered to be the youngest Tertiary unit (uppermost Pliocene) in this area. Sediments forming a barrier-back-barrier sequence fringe most of the southern Maryland-Delaware part of the Delmarva Peninsula and are found at altitudes of as much as 15 m (50 ft) above sea level. This sequence, the Omar Formation, is Sangamon in age and has been dated radiometrically as 60,000 to about 100,000 years old. The microflora in these beds contains no 'exotics,' and the assemblage suggests a warm-temperate environment. The Omar

  9. A cicatriz de Homero em Milton Hatoum

    Directory of Open Access Journals (Sweden)

    Tereza Virginia Ribeiro Barbosa

    2014-04-01

    Full Text Available RESUMO Este ensaio caminha na direção de observar que a literatura do escritor amazonense Milton Hatoum, especificamente o romance Dois irmãos, que ganhou o prêmio Jabuti do ano de 2000, se utiliza de um estratagema muito semelhante àquele inaugurado pela famosa cena da cicatriz de Ulisses do poema épico Odisseia, de Homero. ABSTRACT We will observe one passage of the novel Dois irmãos, de Milton Hatoum, searching for literary memories in Homer's poem Odyssey. We will focus on the famous scene of the footbath in the middle of book 19 of the epopee and contrast it with the tragic scene from Hatoum’s novel in which Omar attacks his brother Yaqub and makes in him a scar.

  10. Encounters with a Syrian - How two worlds converge

    Directory of Open Access Journals (Sweden)

    Lisa Eidenhammer

    2016-12-01

    Full Text Available Two people, from two different cultural backgrounds, with two different pasts, meet each other. The following article deals with the process of these two people´s becoming acquainted. Two years ago, Omar Khir Alanam was forced to leave his native Syria; he eventually arrived in Austria. In the spring of 2015, we met in Graz. We got together frequently, talked about everyday life and Syrian food. However, we never talked about our pasts. After a van attack in Graz on 20 June 2015, in which three people were killed and several badly injured, we became aware of how differently this affected us. Only then, after this horrible incident, did our individual pasts which colored our perceptions of the event become a major topic of interviews and discussions. During the process, the research took on a dialogic character. Only the mutual interest in the seemingly foreign enabled us to understand each other.

  11. New development cycle through long-term investment ?

    Directory of Open Access Journals (Sweden)

    Romain Dittgen

    2011-09-01

    Full Text Available Depuis quelques années, le Gabon nourrit l’ambition de réduire sa dépendance envers les revenus du pétrole et de diversifier son économie. Cette volonté coïncide avec l'augmentation des investissements chinois dans les pays africains richement dotés en ressources. Parmi l’éventail des relations sino-gabonaises, le secteur minier - et surtout le projet de la mine de fer de Bélinga - se place au centre de l'intérêt des deux parties.Sous le règne d’Omar Bongo, ce vaste projet minier avait été promu et présenté comme fleuron de l’économie nationale. Cependant, malgré les promesses de développer les infrastructures et de fournir des opportunités d'emploi, la tentative de diversification économique du Gabon semble toutefois limitée et ne pas vraiment mener vers un changement structurel majeur. Un certain nombre de critères ont par ailleurs retardé la réalisation du projet Bélinga et introduit de nouveaux risques et coûts pour les Chinois. Parmi les plus révélateurs figurent la volatilité des prix des matières premières, la mort du président Omar Bongo en 2009 ainsi que l’opposition croissante de la société civile. L’objectif principal de cet article consiste à étudier les possibilités de développement liées au projet et d’analyser l’approche évolutive de la Chine envers le projetGabon’s recent ambition to reduce its dependency on oil revenue by diversifying its economy coincides with China’s growing investment in resource-rich African countries. Within the wide range of Sino–Gabonese co-operation, the mining sector – and above all the Bélinga iron ore project – is central to both parties’ interests. Omar Bongo’s regime promoted this large-scale project as the flagship of the national economy. However, despite the promise of infrastructure development and employment opportunities, Gabon’s attempt at diversification seems limited and is not leading towards any major structural

  12. Geometrie del senso. Ripensare la semiotica dell’immagine a partire da La macchina della pittura

    Directory of Open Access Journals (Sweden)

    Lucia Corrain

    2012-12-01

    Full Text Available Il contributo intende ripercorrere il ruolo che Omar Calabrese ha avuto nella fondazione della Semiotica dell’arte. Una disciplina che, in Italia, vede la sua nascita a partire dall’ultimo ventennio del secolo scorso e che lo studioso, recentemente scomparso, ha contribuito a delineare con precisione. Il volume La macchina della pittura è sicuramente il suo contributo più innovativo, più sistematico e anc’oggi attuale. All’epoca in cui è stato pubblicato, nel 1985, lanciava una duplice sfida: alla storia dell’arte tradizionale e alla semiotica. Alla prima perché imponeva un altro tipo di sguardo, capace di decifrare il modo in cui attraverso la forma è costruito il senso pittorico. Alla semiotica perché dimostra come la pittura sia in grado di produrre senso e addirittura contenga al suo interno i meccanismi per interpretarla.

  13. Worldwide U.S. Active Duty Military Deaths. Alphabetical Index by Name, 1 October 1979 Through 30 September 1994

    Science.gov (United States)

    1994-09-30

    DE LME NDO G E R A R D O MAR I GZA A I R F O R C E D E LMUNDO L I LY F E D E R I S NAVY D E LOACH B O B B Y D E A N A I R F ORCE D E LOGE B...YAN LAMON EAR LE JAME S ARTHUR EAR LEY KEN W EAR LEY R OB E R T WI L L IAM J R EAR LS M I CHAE L G EAR LS OMAR DALE EAR LY BE N JAMIN J R...8 9 B R OOK LYN E 0 4 2 2 F e b 8 2 KEN TON E 0 7 14 D e c 9 1 R OCKH I L L 0 0 2 1 4 J u l 8 1 T E XAS C I T Y E 0 6 24 Oc t 7 9

  14. Touristic development of the La Lopé National Park (Gabon in light of the SWOT analysis

    Directory of Open Access Journals (Sweden)

    Jędrusik Maciej

    2015-09-01

    Full Text Available The purpose of this article is to evaluate the possibilities of touristic development of the La Lopé National Park and to indicate the most important barriers and limitations of the area exploitation. For this purpose a SWOT method was applied. This assignment presents the situation as of the end of 2014. The majority of the up-to-date data was collected during the mission, the purpose of which was to observe the region, and which was organized by Université Omar Bongo in Libreville and Warsaw University. The La Lopé National Park has a significant touristic potential which is very poorly used. The diagnose of the reasons for that can be an indicator for attempts to rationally use the resources of the region and present an appropriate development strategy.

  15. Cine y literatura

    Directory of Open Access Journals (Sweden)

    Jorge Enrique Adoum

    2015-01-01

    Full Text Available El lanzamiento de la undécima edición de la novela de Jorge Enrique Adoum "Entre Marx y una mujer desnuda" y el comienzo simultáneo de la filmación de la película basada en esa obra, ha puesto nuevamente de relieve, el recurrente tema de la literatura llevada al cine. En ese sentido, en agosto, se llevó a cabo una mesa redonda en la que participaron como exponentes Camilo Luzuriaga (director del filme, Omar Ospina (crítico cinematográfico y jorge Enrique Adoum. En el siguiente artículo -basado en su exposición en la mesa redonda-, el reconocido escritor analiza cómo debe ser para él la vinculación entre literatura y cine.

  16. Christian Metz and the mediatization

    Directory of Open Access Journals (Sweden)

    Oscar TRAVERSA

    2017-07-01

    Full Text Available This paper makes reference to a series of controversial aspects which were awakened by Christian Metz’s work over the course of his active life and are still in the spotlight thirty five years after his demise. The persistence of the wide array of points of view regarding his insights may very well have resulted from both his importance and the epistemological difficulty the different discursive objects entail, especially those of a mixed nature as is the case of cinematography, which unleashed his inquiries. Within the framework of three works dedicated to the author by Dominique Chateau and Martin Lefebvre, Charlotte Bouchez and Omar Hachemi and Eliseo Verón, a set of issues concerning the interplay between Metz’s work and phenomenology, semiotics and discursive specificity are discussed. Finally, this work aims to deal exclusively with those central aspects of the author’s realm which are essential to address the mediatisation processes arising nowadays.

  17. Ebn Farez and Characteristics of his Poetry

    Directory of Open Access Journals (Sweden)

    سردار اصلانی

    2011-09-01

    Full Text Available Abstract     Abou Hafs Omar Ebn Ali known as Ebn Farez is one of the poets of the 6th century. He was famous in the field of poetry. Many great critics like Ebn Khallekan, the writer of Vafiyatolayan also praised him and even regarded him higher than his contemporary poets in position. In this article, we present some features of Soltan Alasheghin Ebn Farez. Ghazal and Khamriyyat are two main types of his poetry. However, his point of view in Khamriyeh is different from Abonavas and others. The reason is that Ebn Farez’s Khamriyyat is full of mystic elements. In addition, in his poetry one can find many uses of literary devices especially pun.

  18. Lower Paleozoic carbonate rocks of Baird Mountains Quadrangle, Alaska

    Energy Technology Data Exchange (ETDEWEB)

    Dumoulin, J.A.; Harris, A.G.

    1985-04-01

    Lower Paleozoic carbonate rocks in the Baird Mountains quadrangle form a relatively thin (about 550 m), chiefly shallow-water succession that has been imbricately thrust and metamorphosed to lower greenschist facies. Middle and Upper Cambrian rocks - the first reported from the western Brooks Range - occur in the northeastern quarter of the quadrangle, south of Angayukaqsraq (formerly Hub) Mountain. They consist of marble grading upward into thin-bedded marble/dolostone couplets and contain pelagiellid mollusks, acetretid brachiopods, and agnostid trilobites. Sedimentologic features and the Pelagiellas indicate a shallow-water depositional environment. Overlying these rocks are Lower and Middle Ordovician marble and phyllite containing graptolites and conodonts of midshelf to basinal aspect. Upper Ordovician rocks in this area are bioturbated to laminated dolostone containing warm, shallow-water conodonts. In the Omar and Squirrel Rivers areas to the west, the Lower Ordovician carbonate rocks show striking differences in lithofacies, biofacies, and thickness. Here they are mainly dolostone with locally well-developed fenestral fabric and evaporite molds, and bioturbated to laminated orange- and gray-weathering dolomitic marble. Upper Silurian dolostone, found near Angayukaqsraq Mountain and on the central Squirrel River, contains locally abundant corals and stronmatoporoids. Devonian carbonate rocks are widely distributed in the Baird Mountains quadrangle; at least two distinct sequences have been identified. In the Omar area, Lower and Middle Devonian dolostone and marble are locally cherty and rich in megafossils. In the north-central (Nakolik River) area, Middle and Upper Devonian marble is interlayered with planar to cross-laminated quartz-carbonate metasandstone and phyllite.

  19. O pedido de cooperação do Tribunal Penal Internacional ao Brasil na captura do presidente do Sudão (The request for cooperation on the capture of the president of Sudan submitted to Brazil by the International Criminal Court

    Directory of Open Access Journals (Sweden)

    João Irineu de Resende Miranda

    2011-01-01

    Full Text Available Resumo: Este artigo tem como tema a relação de cooperação entre o Tribunal Penal Internacional e o Brasil. Partindo das questões levantadas pelo despacho referente à Petição 4625-1, redigido pelo presidente do Supremo Tribunal Federal, seu objetivo é saber se as dificuldades em harmonizar certas disposições do Estatuto do Tribunal Penal Internacional com a Constituição brasileira podem impedir o Brasil de cooperar com o Tribunal Penal Internacional no tocante à detenção e posterior entrega do presidente do Sudão, Omar al-Bashir. Analisando o fundamento jurídico do pedido de cooperação e os pontos de conflito apontados pela doutrina, conclui-se que não há obstáculo para o atendimento do pedido de cooperação, sendo este, pelo contrário, uma obrigação jurídica do Estado brasileiro.Abstract: This work discusses the cooperation relationship between the International Criminal Court and Brazil. From the issues raised by the order on the Petition 4625-1, as written by the President of the Supreme Court, its goal is to establish whether or not the difficulties in harmonizing certain provisions of the Statute of the International Criminal Court with the Brazilian Constitution may prevent the latter to cooperate with the International Criminal Court in relation to the arrest and surrender of the President of Sudan, Omar al-Bashir. Analyzing the legal basis of the request for cooperation and the conflict points highlighted by the doctrine, our research concludes that there is no obstacle to comply with the request for cooperation, which is actually a legal obligation of the Brazilian state.

  20. Study of mineral chemistry, thermobarometry and petrogenesis of migmatitic rocks of Hamedan area

    Directory of Open Access Journals (Sweden)

    Ali Asghar Sepahi Gerow

    2018-03-01

    Full Text Available In the Hamedan region, migmatitic rocks occur with various structures. In the Simin area (South Hamedan stromatic and in the Darreh-Omar (Toyserkan area ophtalmitic structures are abundant. Migmatites have been developed in a poly-metamorphic region. At least one regional metamorphism and two contact metamorphism by mafic and felsic intrusions occurred in the area. It seems that in the Darreh-Omar area contact metamorphism of mafic body leading to migmatization, But in the Simin area previous regional metamorphism and development of shear zones followed by contact metamorphism by felsic body. Therefore, in some areas, such as the Simin area, the migmatization may have occurred in more than one stage. These are consistent with recent geochronological studies of the Alvand plutonic body and surrounding metamorphic rocks. Index minerals of metapelites such as garnet (almandine, biotite (siderophyllite, staurolite, andalusite, sillimanite, kyanite, fibrolite, cordierite, plagioclase (andesine and spinel (hercynite are existing in these rocks. Field geology, petrographic and geochemical evidences suggest that different generations of staurolite, biotite and cordierite exist in metamorphic rocks of different grades in the Hamadan area. These minerals sometimes have been formed by progressive reactions and some other times from retrogressive reactions. A number of these phases have been formed at the peak of metamorphism and some others in later time. Based on thermometric cation-exchange method of garnet-biotite pair, using different calibrations, the obtained temperature using first-generation of biotites is 655 °C and temperature range of 529 °C for second-generation biotites. Cordierite-garnet thermometry indicates a temperature of 637 °C for related migmatitic rocks. In barometry with GPBQ system, calculated pressure for first-generation biotite is estimated to be about 3.9 kbar and for the second-generation biotite around 3.6 kbar.

  1. Platelet Counts, MPV and PDW in Culture Proven and Probable Neonatal Sepsis and Association of Platelet Counts with Mortality Rate

    International Nuclear Information System (INIS)

    Ahmad, M. S.; Waheed, A.

    2014-01-01

    Objective: To determine frequency of thrombocytopenia and thrombocytosis, the MPV (mean platelet volume) and PDW (platelet distribution width) in patients with probable and culture proven neonatal sepsis and determine any association between platelet counts and mortality rate. Study Design: Descriptive analytical study. Place and Duration of Study: NICU, Fazle Omar Hospital, from January 2011 to December 2012. Methodology: Cases of culture proven and probable neonatal sepsis, admitted in Fazle Omar Hospital, Rabwah, were included in the study. Platelet counts, MPV and PDW of the cases were recorded. Mortality was documented. Frequencies of thrombocytopenia ( 450000/mm3) were ascertained. Mortality rates in different groups according to platelet counts were calculated and compared by chi-square test to check association. Results: Four hundred and sixty nine patients were included; 68 (14.5%) of them died. One hundred and thirty six (29%) had culture proven sepsis, and 333 (71%) were categorized as probable sepsis. Thrombocytopenia was present in 116 (24.7%), and thrombocytosis was present in 36 (7.7%) cases. Median platelet count was 213.0/mm3. Twenty eight (27.7%) patients with thrombocytopenia, and 40 (12.1%) cases with normal or raised platelet counts died (p < 0.001). Median MPV was 9.30, and median PDW was 12.30. MPV and PDW of the patients who died and who were discharged were not significantly different from each other. Conclusion: Thrombocytopenia is a common complication of neonatal sepsis. Those with thrombocytopenia have higher mortality rate. No significant difference was present between PDW and MPV of the cases who survived and died. (author)

  2. Vikergallup : eesti kirjandus 2008 / Peeter Helme, Ott Kilusk, Igor Kotjuh... [jt.

    Index Scriptorium Estoniae

    2009-01-01

    21 arvustaja vastus küsimusele, milline oli 2008. aasta parim uudisteos ja debüüt. Ära nimetati fs-i luulekogu "Alasti ja elus", Andrei Hvostovi proosaraamatut "Võõrad lood", Maarja Kangro luulekogu "Heureka", Kalju Kruusa luulekogu "Pilvedgi mindgi liigutavadgi", Asko Künnapi luulekogu "Su ööd on loetud", Elo Viidingu proosaraamatut "Püha Maama", Mart Juure luulekogu "Pane Eesti peale tagasi", Jaan Kaplisnki luulekogu "Teiselpool järve", Mart Kivastiku proosaraamatut "Kurb raamat", Leo Kunnase romaani "Gort Ashryn I", Andres Langemetsa luulekogu "Vooder", Erkki Luugi "Valitud luuletusi", Rein Põdra romaani "Juba olnud", Rein Raua lühiromaani "Vend" ja Jaan Tangsoo romaani "Méduse'i parv". Parima debüüdina mainiti Andrus Kasemaa luulekogu "Poeedirahu", Barthol Lo Mejori proosaraamatut "Popdada" ja Chaneldiori proosaraamatut "Kontrolli alt väljas", Lauri Saatpalu laulutekstiraamatut "Nähtused ja tehtused", Tamur Kusnetsi romaani "Hundipäikese aeg" ja Jaanika Merilo luulekogu "Rütmist väljas"

  3. Immunotherapeutic Potential of Oncolytic H-1 Parvovirus: Hints of Glioblastoma Microenvironment Conversion towards Immunogenicity.

    Science.gov (United States)

    Angelova, Assia L; Barf, Milena; Geletneky, Karsten; Unterberg, Andreas; Rommelaere, Jean

    2017-12-15

    Glioblastoma, one of the most aggressive primary brain tumors, is characterized by highly immunosuppressive microenvironment. This contributes to glioblastoma resistance to standard treatment modalities and allows tumor growth and recurrence. Several immune-targeted approaches have been recently developed and are currently under preclinical and clinical investigation. Oncolytic viruses, including the autonomous protoparvovirus H-1 (H-1PV), show great promise as novel immunotherapeutic tools. In a first phase I/IIa clinical trial (ParvOryx01), H-1PV was safe and well tolerated when locally or systemically administered to recurrent glioblastoma patients. The virus was able to cross the blood-brain (tumor) barrier after intravenous infusion. Importantly, H-1PV treatment of glioblastoma patients was associated with immunogenic changes in the tumor microenvironment. Tumor infiltration with activated cytotoxic T cells, induction of cathepsin B and inducible nitric oxide (NO) synthase (iNOS) expression in tumor-associated microglia/macrophages (TAM), and accumulation of activated TAM in cluster of differentiation (CD) 40 ligand (CD40L)-positive glioblastoma regions was detected. These are the first-in-human observations of H-1PV capacity to switch the immunosuppressed tumor microenvironment towards immunogenicity. Based on this pilot study, we present a tentative model of H-1PV-mediated modulation of glioblastoma microenvironment and propose a combinatorial therapeutic approach taking advantage of H-1PV-induced microglia/macrophage activation for further (pre)clinical testing.

  4. Parvovirus transmission by blood products - a cause for concern?

    Science.gov (United States)

    Norja, Päivi; Lassila, Riitta; Makris, Mike

    2012-11-01

    The introduction of dual viral inactivation of clotting factor concentrates has practically eliminated infections by viruses associated with significant pathogenicity over the last 20 years. Despite this, theoretical concerns about transmission of infection have remained, as it is known that currently available viral inactivation methods are unable to eliminate parvovirus B19 or prions from these products. Recently, concern has been raised following the identification of the new parvoviruses, human parvovirus 4 (PARV4) and new genotypes of parvovirus B19, in blood products. Parvoviruses do not cause chronic pathogenicity similar to human immunodeficiency virus or hepatitis C virus, but nevertheless may cause clinical manifestations, especially in immunosuppressed patients. Manufacturers should institute measures, such as minipool polymerase chain reaction testing, to ensure that their products contain no known viruses. So far, human bocavirus, another new genus of parvovirus, has not been detected in fractionated blood products, and unless their presence can be demonstrated, routine testing during manufacture is not essential. Continued surveillance of the patients and of the safety of blood products remains an important ongoing issue. © 2012 Blackwell Publishing Ltd.

  5. Transcriptional profiling at whole population and single cell levels reveals somatosensory neuron molecular diversity

    Science.gov (United States)

    Chiu, Isaac M; Barrett, Lee B; Williams, Erika K; Strochlic, David E; Lee, Seungkyu; Weyer, Andy D; Lou, Shan; Bryman, Gregory S; Roberson, David P; Ghasemlou, Nader; Piccoli, Cara; Ahat, Ezgi; Wang, Victor; Cobos, Enrique J; Stucky, Cheryl L; Ma, Qiufu; Liberles, Stephen D; Woolf, Clifford J

    2014-01-01

    The somatosensory nervous system is critical for the organism's ability to respond to mechanical, thermal, and nociceptive stimuli. Somatosensory neurons are functionally and anatomically diverse but their molecular profiles are not well-defined. Here, we used transcriptional profiling to analyze the detailed molecular signatures of dorsal root ganglion (DRG) sensory neurons. We used two mouse reporter lines and surface IB4 labeling to purify three major non-overlapping classes of neurons: 1) IB4+SNS-Cre/TdTomato+, 2) IB4−SNS-Cre/TdTomato+, and 3) Parv-Cre/TdTomato+ cells, encompassing the majority of nociceptive, pruriceptive, and proprioceptive neurons. These neurons displayed distinct expression patterns of ion channels, transcription factors, and GPCRs. Highly parallel qRT-PCR analysis of 334 single neurons selected by membership of the three populations demonstrated further diversity, with unbiased clustering analysis identifying six distinct subgroups. These data significantly increase our knowledge of the molecular identities of known DRG populations and uncover potentially novel subsets, revealing the complexity and diversity of those neurons underlying somatosensation. DOI: http://dx.doi.org/10.7554/eLife.04660.001 PMID:25525749

  6. Arhitektuurivõistlused 2007 / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2007-01-01

    Tulemused: Eesti Rahvusringhäälingu hoone arhitektuurse idee konkurss (I - E. Nobel), Paide kutsekeskkoolide uue hoonekompleksi arhitektuurivõistlus (I - M. Tüür, V. Tomiste, O. Kadarik, Kosmos), Prantsuse Lütseumi spordihoone ideekonkurss (I - T. Laigu, K. Ojaliiv, M. Rass, EMP A&I), Volta kvartali kutsutud osalejatega ideevõistlus (I - AW2 Arkkitehtit), aasta betoonehitis 2006 - Luku-Experdi büroohoone (H. Kesler), Eesti Vabadussõja võidusamba võistlus (I - R. Sternfeld, A. Laidre, K. Kiho, A. Savi), Tabasalu alevikukeskuse hoonestuse kutsutud osalejatega ideevõistlus (I - T. Laigu, K. Ojaliiv, QP Arhitektid), Tamsalu linna keskosa ruumilise planeerimise avalik arhitektuurivõistlus (I - T. Skolimowski, K. Süda, A. Vaher, R. Parve, ASE), Eesti Vabaõhumuuseumi külastuskeskuse, ennistuskoja Kanut ja Tallinna muuseumide ühishoidla arhitektuurse idee võistlus (I - S. Vallner, I. Peil), Patarei ja lennusadama ala mahulise planeerimise rahvusvaheline ideevõistlus (I - I. Lubjak, S. Laanjärv), parim puitehitis 2007 - eramu Kiili vallas (K. Tõra, A. Sokk, T. Peipman), Keila Tuula tee 5 planeeringu võistlus (I - A. Uogintas, M. Podagelyte, M. Cirtautas)

  7. Non-invasive methods for estimating mPAP in COPD using cardiovascular magnetic resonance imaging

    International Nuclear Information System (INIS)

    Johns, C.S.; Capener, D.A.; Oram, C.; Wild, J.M.; Rajaram, S.; Elliot, C.; Condliffe, R.; Kiely, D.G.; Swift, A.J.

    2018-01-01

    Pulmonary hypertension (PH) is associated with a poor outcome in chronic obstructive pulmonary disease (COPD) and is diagnosed invasively. We aimed to assess the diagnostic accuracy and prognostic value of non-invasive cardiovascular magnetic resonance (CMR) models. Patients with COPD and suspected PH, who underwent CMR and right heart catheter (RHC) were identified. Three candidate models were assessed: 1, CMR-RV model, based on right ventricular (RV) mass and interventricular septal angle; 2, CMR PA/RV includes RV mass, septal angle and pulmonary artery (PA) measurements; 3, the Alpha index, based on RV ejection fraction and PA size. Of 102 COPD patients, 87 had PH. The CMR-PA/RV model had the strongest diagnostic accuracy (sensitivity 92%, specificity 80%, positive predictive value 96% and negative predictive value 63%, AUC 0.93, p<0.0001). Splitting RHC-mPAP, CMR-RV and CMR-PA/RV models by 35mmHg gave a significant difference in survival, with log-rank chi-squared 5.03, 5.47 and 7.10. RV mass and PA relative area change were the independent predictors of mortality at multivariate Cox regression (p=0.002 and 0.030). CMR provides diagnostic and prognostic information in PH-COPD. The CMR-PA/RV model is useful for diagnosis, the RV mass index and PA relative area change are useful to assess prognosis. (orig.)

  8. Update of the human parvovirus B19 biology.

    Science.gov (United States)

    Servant-Delmas, A; Morinet, F

    2016-02-01

    Since its discovery, the human parvovirus B19 (B19V) has been associated with many clinical situations in addition to the prototype clinical manifestations, i.e. erythema infectiosum and erythroblastopenia crisis. The clinical significance of the viral B19V DNA persistence in sera after acute infection remains largely unknown. Such data may constitute a new clinical entity and is discussed in this manuscript. In 2002, despite the genetic diversity among B19V viruses has been reported to be very low, the description of markedly distinct sequences showed a new organization into three genotypes. The most recent common ancestor for B19V genotypes was estimated at early 1800s. B19V replication is enhanced by hypoxia and this might to explain the high viral load detected by quantitative PCR in the sera of infected patients. The minimum infectious dose necessary to transmit B19V infection by the transfusion of labile blood products remains unclear. At the opposite, the US Food and Drug Administration proposed a limit of 10(4)IU/mL of viral DNA in plasma pools used for the production of plasma derivatives. Recently, a new human parvovirus (PARV4) has been discovered. The consequences on blood transfusion of this blood-borne agent and its pathogenicity are still unknown. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  9. L’aggressività della coppia criminale: la strage di Erba analizzata nell’ottica della coscienza intersoggettiva di D. Stern/L'agressivité des couples criminels : le massacre de Erba analysé par l'approche de la conscience intersubjective de Daniel Stern/The agressiveness of the criminal couples: the analysed massacre of Erba using the approach of the intersubjective conscience of Daniel Stern

    Directory of Open Access Journals (Sweden)

    Pasquale Caponnetto

    2013-12-01

    Full Text Available La coppia criminale è un fenomeno poco comune nell'ambito dei delitti in quanto la maggior parte dei criminali commette il crimine da solo o coinvolge altri individui solo per caso. Ciò nonostante, la letteratura rivela una serie di coppie criminali che hanno commesso diversi crimini, fino ad arrivare all’omicidio. Alcuni hanno ucciso per denaro, altri per odio, altri ancora per amore, per vendetta, per perversione. Bonnie e Clyde, Olindo e Rosa, Erika e Omar sono espressione di un viaggio nel fenomeno del “crimine di coppia” in cui manifestazioni di follia a due, al di là dell’infatuazione reciproca e della dipendenza psicologica, si svuotano di qualsiasi accezione romantica per concretizzarsi in qualcosa di spaventoso e incontenibile, capace di sfuggire ad ogni tipo di catalogazione e comprensione. Nel presente lavoro, in particolare, si andrà ad analizzare la coppia criminale degli autori della strage di Erba, che verrà esaminata nell’ottica della coscienza intersoggettiva di Stern. Le couple criminel est un phénomène rare puisque la majorité des crimes sont commis par des criminels seuls ou ce n’est que par hasard qu’ils impliquent d’autres personnes. Toutefois, la littérature parle d’une série de couples criminels qui ont commis des différents types de crimes (homicide inclus. Certains d’entre eux tuent pour de l’argent, certains autres à cause de la haine, de l’amour, de la revanche ou de la perversion. Bonnie et Clyde, Olindo et Rosa, Erika et Omar constituent des exemples du phénomène du « crime en couple ». Ce sont des situations de folie à deux qui n’ont aucune acception romantique et qui se traduisent en quelque chose d’horrifiant et d’incontrôlé. Dans cet article, les auteurs vont analyser le couple criminel composé par les responsables du massacre de Erba (Italie du Nord. L’objectif est d’examiner ce couple en utilisant l’approche de la conscience intersubjective de Daniel

  10. Approaches to reducing photon dose calculation errors near metal implants

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Jessie Y.; Followill, David S.; Howell, Rebecca M.; Mirkovic, Dragan; Kry, Stephen F., E-mail: sfkry@mdanderson.org [Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030 and Graduate School of Biomedical Sciences, The University of Texas Health Science Center Houston, Houston, Texas 77030 (United States); Liu, Xinming [Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030 and Graduate School of Biomedical Sciences, The University of Texas Health Science Center Houston, Houston, Texas 77030 (United States); Stingo, Francesco C. [Department of Biostatistics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030 and Graduate School of Biomedical Sciences, The University of Texas Health Science Center Houston, Houston, Texas 77030 (United States)

    2016-09-15

    Purpose: Dose calculation errors near metal implants are caused by limitations of the dose calculation algorithm in modeling tissue/metal interface effects as well as density assignment errors caused by imaging artifacts. The purpose of this study was to investigate two strategies for reducing dose calculation errors near metal implants: implementation of metal-based energy deposition kernels in the convolution/superposition (C/S) dose calculation method and use of metal artifact reduction methods for computed tomography (CT) imaging. Methods: Both error reduction strategies were investigated using a simple geometric slab phantom with a rectangular metal insert (composed of titanium or Cerrobend), as well as two anthropomorphic phantoms (one with spinal hardware and one with dental fillings), designed to mimic relevant clinical scenarios. To assess the dosimetric impact of metal kernels, the authors implemented titanium and silver kernels in a commercial collapsed cone C/S algorithm. To assess the impact of CT metal artifact reduction methods, the authors performed dose calculations using baseline imaging techniques (uncorrected 120 kVp imaging) and three commercial metal artifact reduction methods: Philips Healthcare’s O-MAR, GE Healthcare’s monochromatic gemstone spectral imaging (GSI) using dual-energy CT, and GSI with metal artifact reduction software (MARS) applied. For the simple geometric phantom, radiochromic film was used to measure dose upstream and downstream of metal inserts. For the anthropomorphic phantoms, ion chambers and radiochromic film were used to quantify the benefit of the error reduction strategies. Results: Metal kernels did not universally improve accuracy but rather resulted in better accuracy upstream of metal implants and decreased accuracy directly downstream. For the clinical cases (spinal hardware and dental fillings), metal kernels had very little impact on the dose calculation accuracy (<1.0%). Of the commercial CT artifact

  11. Approaches to reducing photon dose calculation errors near metal implants

    International Nuclear Information System (INIS)

    Huang, Jessie Y.; Followill, David S.; Howell, Rebecca M.; Mirkovic, Dragan; Kry, Stephen F.; Liu, Xinming; Stingo, Francesco C.

    2016-01-01

    Purpose: Dose calculation errors near metal implants are caused by limitations of the dose calculation algorithm in modeling tissue/metal interface effects as well as density assignment errors caused by imaging artifacts. The purpose of this study was to investigate two strategies for reducing dose calculation errors near metal implants: implementation of metal-based energy deposition kernels in the convolution/superposition (C/S) dose calculation method and use of metal artifact reduction methods for computed tomography (CT) imaging. Methods: Both error reduction strategies were investigated using a simple geometric slab phantom with a rectangular metal insert (composed of titanium or Cerrobend), as well as two anthropomorphic phantoms (one with spinal hardware and one with dental fillings), designed to mimic relevant clinical scenarios. To assess the dosimetric impact of metal kernels, the authors implemented titanium and silver kernels in a commercial collapsed cone C/S algorithm. To assess the impact of CT metal artifact reduction methods, the authors performed dose calculations using baseline imaging techniques (uncorrected 120 kVp imaging) and three commercial metal artifact reduction methods: Philips Healthcare’s O-MAR, GE Healthcare’s monochromatic gemstone spectral imaging (GSI) using dual-energy CT, and GSI with metal artifact reduction software (MARS) applied. For the simple geometric phantom, radiochromic film was used to measure dose upstream and downstream of metal inserts. For the anthropomorphic phantoms, ion chambers and radiochromic film were used to quantify the benefit of the error reduction strategies. Results: Metal kernels did not universally improve accuracy but rather resulted in better accuracy upstream of metal implants and decreased accuracy directly downstream. For the clinical cases (spinal hardware and dental fillings), metal kernels had very little impact on the dose calculation accuracy (<1.0%). Of the commercial CT artifact

  12. Prevalence of nucleic acid sequences specific for human parvoviruses, hepatitis A and hepatitis E viruses in coagulation factor concentrates.

    Science.gov (United States)

    Modrow, S; Wenzel, J J; Schimanski, S; Schwarzbeck, J; Rothe, U; Oldenburg, J; Jilg, W; Eis-Hübinger, A M

    2011-05-01

    Due to their high resistance to inactivation procedures, nonenveloped viruses such as parvovirus B19, human bocavirus (HBoV), human parvovirus 4 (PARV4), hepatitis A (HAV) and hepatitis E virus (HEV) pose a particular threat to blood products. Virus transmission to patients treated with blood products presents an additional burden to disease. We determined the frequency and the amount of nucleic acid specific for nonenveloped viruses in recently manufactured preparations of commercial coagulation factor concentrates. At least three different batches of each of 13 different plasma-derived and recombinant coagulation factor products were tested for the presence and the amount of nucleic acid for parvovirus B19, HBoV, human parvovirus 4, hepatitis A virus and HEV by using quantitative polymerase chain reaction. Whereas none of the recombinant products tested positive for any of these viruses, parvovirus B19 DNA with amounts ranging between 2×10(1) and 1.3×10(3) genome equivalents/ml was detected in five plasma-derived products. In addition to parvovirus B19 genotype 1, genotypes 2 and 3 were observed in two batches of a factor VIII/von-Willebrand factor product. In two products (one factor VIII concentrate and one activated prothrombin complex concentrate), a combination of both genotypes 1 and 2 of parvovirus B19 was detected. The data show that nucleic acids from several relevant nonenveloped viruses are not found at detectable levels in coagulation factor concentrates. In some cases, parvovirus B19 DNA was detectable at low levels. Testing of the plasma pools for the full range of parvovirus genotypes is advocated for ensuring product safety. © 2010 The Author(s). Vox Sanguinis © 2010 International Society of Blood Transfusion.

  13. Purification and characterization of parvalbumins, the major allergens in red stingray (Dasyatis akajei).

    Science.gov (United States)

    Cai, Qiu-Feng; Liu, Guang-Ming; Li, Teng; Hara, Kenji; Wang, Xi-Chang; Su, Wen-Jin; Cao, Min-Jie

    2010-12-22

    Fish has received increasing attention because it induces IgE-mediated food allergy. Parvalbumin (PV) represents the major allergen of fish, and IgE cross-reactivity to PV in various teleost fish species has been shown, while little information is available about allergens in elasmobranch fish. In this study, two PV isoforms (named as PV-I and PV-II) from red stingray (Dasyatis akajei) were purified to homogeneity by a series of procedures including ammonium sulfate precipitation and column chromatographies of DEAE-Sepharose and Sephacryl S-200. Purified PVs revealed a single band on tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The molecular masses of PV-I and PV-II were 12.29 and 11.95 kDa, respectively, as determined by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Western blot using antifrog PV monoclonal antibody (PARV-19) showed positive reactions to the two proteins, confirming that they were PVs, although their immunological reactivities were weaker than those of PV from silver carp. The N-terminal amino acid sequence of PV-I was determined, and comparison with PVs from other fish species showed low homology between teleost and elasmobranch fish. The isoelectric points of PV-I and PV-II were 5.4 and 5.0, respectively, as determined by two-dimensional electrophoresis (2-DE), suggesting that both isoforms belong to the α-group. IgE immunoblotting analysis showed that sera from fish-allergic patients reacted to both PV-I and PV-II from red stingray. Thermal stability revealed that PV-I easily formed oligomers than PV-II, which might contribute to the maintenance of its allerginicity during heat processing.

  14. Oncolytic effects of parvovirus H-1 in medulloblastoma are associated with repression of master regulators of early neurogenesis.

    Science.gov (United States)

    Lacroix, Jeannine; Schlund, Franziska; Leuchs, Barbara; Adolph, Kathrin; Sturm, Dominik; Bender, Sebastian; Hielscher, Thomas; Pfister, Stefan M; Witt, Olaf; Rommelaere, Jean; Schlehofer, Jörg R; Witt, Hendrik

    2014-02-01

    Based on extensive pre-clinical studies, the oncolytic parvovirus H-1 (H-1PV) is currently applied to patients with recurrent glioblastoma in a phase I/IIa clinical trial (ParvOryx01, NCT01301430). Cure rates of about 40% in pediatric high-risk medulloblastoma (MB) patients also indicate the need of new therapeutic approaches. In order to prepare a future application of oncolytic parvovirotherapy to MB, the present study preclinically evaluates the cytotoxic efficacy of H-1PV on MB cells in vitro and characterizes cellular target genes involved in this effect. Six MB cell lines were analyzed by whole genome oligonucleotide microarrays after treatment and the results were matched to known molecular and cytogenetic risk factors. In contrast to non-transformed infant astrocytes and neurons, in five out of six MB cell lines lytic H-1PV infection and efficient viral replication could be demonstrated. The cytotoxic effects induced by H-1PV were observed at LD50s below 0.05 p. f. u. per cell indicating high susceptibility. Gene expression patterns in the responsive MB cell lines allowed the identification of candidate target genes mediating the cytotoxic effects of H-1PV. H-1PV induced down-regulation of key regulators of early neurogenesis shown to confer poor prognosis in MB such as ZIC1, FOXG1B, MYC, and NFIA. In MB cell lines with genomic amplification of MYC, expression of MYC was the single gene most significantly repressed after H-1PV infection. H-1PV virotherapy may be a promising treatment approach for MB since it targets genes of functional relevance and induces cell death at very low titers of input virus. Copyright © 2013 The Authors. Published by Wiley Periodicals, Inc. on behalf of UICC.

  15. Optimization of tomotherapy treatment planning for patients with bilateral hip prostheses.

    Science.gov (United States)

    Chapman, David; Smith, Shaun; Barnett, Rob; Bauman, Glenn; Yartsev, Slav

    2014-02-04

    To determine the effect of different imaging options and the most efficient imaging strategy for treatment planning of patients with hip prostheses. The planning kilovoltage CT (kVCT) and daily megavoltage CT (MVCT) studies for three prostate cancer patients with bilateral hip prostheses were used for creating hybrid kVCT/MVCT image sets. Treatment plans were created for kVCT images alone, hybrid kVCT/MVCT images, and MVCT images alone using the same dose prescription and planning parameters. The resulting dose volume histograms were compared. The orthopedic metal artifact reduction (O-MAR) reconstruction tool for kVCT images and different MVCT options were investigated with a water tank fit with double hip prostheses. Treatment plans were created for all imaging options and calculated dose was compared with the one measured by a pin-point ion chamber. On average for three patients, the D35% for the bladder was 8% higher in plans based on MVCT images and 7% higher in plans based on hybrid images, compared to the plans based on kVCT images alone. Likewise, the D35% for the rectum was 3% higher than the kVCT based plan for both hybrid and MVCT plans. The average difference in planned D99% in the PTV compared to kVCT plans was 0.9% and 0.1% for MVCT and hybrid plans, respectively. For the water tank with hip prostheses phantom, the kVCT plan with O-MAR correction applied showed better agreement between the measured and calculated dose than the original image set, with a difference of -1.9% compared to 3.3%. The measured doses for the MVCT plans were lower than the calculated dose due to image size limitations. The best agreement was for the kVCT/MVCT hybrid plans with the difference between calculated and measured dose around 1%. MVCT image provides better visualization of patient anatomy and hybrid kVCT/MVCT study enables more accurate calculations using updated MVCT relative electron density calibration.

  16. Optimization of tomotherapy treatment planning for patients with bilateral hip prostheses

    International Nuclear Information System (INIS)

    Chapman, David; Smith, Shaun; Barnett, Rob; Bauman, Glenn; Yartsev, Slav

    2014-01-01

    To determine the effect of different imaging options and the most efficient imaging strategy for treatment planning of patients with hip prostheses. The planning kilovoltage CT (kVCT) and daily megavoltage CT (MVCT) studies for three prostate cancer patients with bilateral hip prostheses were used for creating hybrid kVCT/MVCT image sets. Treatment plans were created for kVCT images alone, hybrid kVCT/MVCT images, and MVCT images alone using the same dose prescription and planning parameters. The resulting dose volume histograms were compared. The orthopedic metal artifact reduction (O-MAR) reconstruction tool for kVCT images and different MVCT options were investigated with a water tank fit with double hip prostheses. Treatment plans were created for all imaging options and calculated dose was compared with the one measured by a pin-point ion chamber. On average for three patients, the D 35% for the bladder was 8% higher in plans based on MVCT images and 7% higher in plans based on hybrid images, compared to the plans based on kVCT images alone. Likewise, the D 35% for the rectum was 3% higher than the kVCT based plan for both hybrid and MVCT plans. The average difference in planned D99% in the PTV compared to kVCT plans was 0.9% and 0.1% for MVCT and hybrid plans, respectively. For the water tank with hip prostheses phantom, the kVCT plan with O-MAR correction applied showed better agreement between the measured and calculated dose than the original image set, with a difference of -1.9% compared to 3.3%. The measured doses for the MVCT plans were lower than the calculated dose due to image size limitations. The best agreement was for the kVCT/MVCT hybrid plans with the difference between calculated and measured dose around 1%. MVCT image provides better visualization of patient anatomy and hybrid kVCT/MVCT study enables more accurate calculations using updated MVCT relative electron density calibration

  17. Dictatures et protestantisme en Afrique Noire depuis la décolonisation: le résultat d'une politique françafricaine et d'une influence américaine certaine

    Directory of Open Access Journals (Sweden)

    Jérémie Kroubo Dagnini

    2009-12-01

    Full Text Available Félix Houphouët-Boigny, Étienne Gnassingbé Eyadéma, Jean Bédel Bokassa, Denis Sassou-Nguesso, El Hadj Omar Bongo, Idriss Déby, Paul Biya et Blaise Compaoré, por citar sólo algunos, tienen un mismo punto en común : fueron o son « amigos de Francia » que recibieron la ayuda económica, financiera, política y militar de presidentes franceses sucesivos, de Charles de Gaulle a Nicolas Sarkozy. Estos dictadores africanos constituyen el resultado directo de la política africana de Francia después de los últimos cincuenta años. Paralelamente a este neocolonialismo francés, otra forma de imperialismo se ha desarrollado en el África negra: la conquista religiosa de las iglesias evangélicas americanas. La presencia de los evangélicos americanos en África es muy clara: compensar el retraso político de América en la conquista colonial. Pero este imperialismo religioso no sucede sin consecuencias: ha originado graves divergencias sectarias. Así, este estudio, en una primera parte, expone la política africana de Francia y el apoyo que aporta a las antiguas colonias africanas. La segunda parte propone explorar el rol, la influencia y las consecuencias de las misiones protestantes en el África negra.__________________ABSTRACT:Félix Houphouët-Boigny, Étienne Gnassingbé Eyadéma, Jean Bédel Bokassa, Denis Sassou-Nguesso, El Hadj Omar Bongo, Idriss Déby Paul Biya and Blaise Compaoré, to mention only a few, have one thing in common: they are, or were, “friends of France”, who received economic, financial, political and military help from successive French presidents, from Charles de Gaulle to Nicolas Sarkozy. Those African dictators are a direct result of the French policy in Africa during the last fifty years. In parallel with this French neo-colonialism, another form of imperialism has developed in Black Africa: the religious conquest of the American Protestant churches. The presence of the American Protestants in Africa is

  18. SU-F-J-161: Prostate Contouring in Patients with Bilateral Hip Prostheses: Impact of Using Artifact-Reduced CT Images and MRI

    Energy Technology Data Exchange (ETDEWEB)

    Elzibak, A; Loblaw, A; Morton, G; Vesprini, D; Liu, S; Chung, H; Davidson, M [Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario (Canada)

    2016-06-15

    Purpose: To investigate the usefulness of metal artifact reduction in CT images of patients with bilateral hip prostheses (BHP) for contouring the prostate and determine if the inclusion of MR images provides additional benefits. Methods: Five patients with BHP were CT scanned using our clinical protocol (140kV, 300mAs, 3mm slices, 1.5mm increment, Philips Medical Systems, OH). Images were reconstructed with the orthopaedic metal artifact reduction (O-MAR) algorithm. MRI scanning was then performed (1.5T, GE Healthcare, WI) with a flat table-top (T{sub 2}-weighted, inherent body coil, FRFSE, 3mm slices with 0mm gap). All images were transferred to Pinnacle (Version 9.2, Philips Medical Systems). For each patient, two data sets were produced: one containing the O-MAR-corrected CT images and another containing fused MRI and O-MAR-corrected CT images. Four genito-urinary radiation oncologists contoured the prostate of each patient on the O-MAR-corrected CT data. Two weeks later, they contoured the prostate on the fused data set, blinded to all other contours. During each contouring session, the oncologists reported their confidence in the contours (1=very confident, 3=not confident) and the contouring difficulty that they experienced (1=really easy, 4=very challenging). Prostate volumes were computed from the contours and the conformity index was used to evaluate inter-observer variability. Results: Larger prostate volumes were found on the O-MAR-corrected CT set than on the fused set (p< 0.05, median=36.9cm{sup 3} vs. 26.63 cm{sup 3}). No significant differences were noted in the inter-observer variability between the two data sets (p=0.3). Contouring difficulty decreased with the addition of MRI (p<0.05) while the radiation oncologists reported more confidence in their contours when MRI was fused with the O-MAR-corrected CT data (p<0.05). Conclusion: This preliminary work demonstrated that, while O-MAR correction to CT images improves visualization of anatomy, the

  19. Using Social Media to Characterize Public Sentiment Toward Medical Interventions Commonly Used for Cancer Screening: An Observational Study.

    Science.gov (United States)

    Metwally, Omar; Blumberg, Seth; Ladabaum, Uri; Sinha, Sidhartha R

    2017-06-07

    Although cancer screening reduces morbidity and mortality, millions of people worldwide remain unscreened. Social media provide a unique platform to understand public sentiment toward tools that are commonly used for cancer screening. The objective of our study was to examine public sentiment toward colonoscopy, mammography, and Pap smear and how this sentiment spreads by analyzing discourse on Twitter. In this observational study, we classified 32,847 tweets (online postings on Twitter) related to colonoscopy, mammography, or Pap smears using a naive Bayes algorithm as containing positive, negative, or neutral sentiment. Additionally, we characterized the spread of sentiment on Twitter using an established model to study contagion. Colonoscopy-related tweets were more likely to express negative than positive sentiment (negative to positive ratio 1.65, 95% CI 1.51-1.80, Psocial media data provides a unique, quantitative framework to better understand the public's perception of medical interventions that are commonly used for cancer screening. Given the growing use of social media, public health interventions to improve cancer screening should use the health perceptions of the population as expressed in social network postings about tests that are frequently used for cancer screening, as well as other people they may influence with such postings. ©Omar Metwally, Seth Blumberg, Uri Ladabaum, Sidhartha R. Sinha. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 07.06.2017.

  20. Life and Death on the Pulse Dance Floor: Transglocal Politics and Erasure of the Latinx in the History of Queer Dance Culture

    Directory of Open Access Journals (Sweden)

    Tim Lawrence

    2016-11-01

    Full Text Available Although the dominant response of politicians, journalists and campaign groups to Omar Mateen’s 12 June 2016 massacre of forty-nine people at the Pulse nightclub in Orlando revolved around the repetition of already established arguments about terrorism, this article will outline how the massacre amounted to a specific attack on the Latinx community. It will also argue that, although distinctive, the discursive erasure of the specifically queer Latinx finds a partial echo in the way that Latin culture has been marginalised in writing on dance culture. An outline map of the somewhat opaque Latinx contribution will be offered as a small tribute to those who have lived for and now died on the Latinx dance floor. The account of the dancers who gathered at Pulse, the music they danced to, and the unstable, marginalised and dynamic networks of musicians, dancers and party spaces that preceded them will be considered within J. Blake Scott and Rebecca Dingo’s (2012 evocation of the “transglocal”. If transglocal encounters “can generate new meanings and subject positions” (Blake Scott and Dingo: 7, so the dancers at Pulse can be seen to have moved resourcefully, dynamically and creatively between the local and the transnational as they sought out new modes of expression and community in a darkening global terrain.

  1. A field trail for sealing abandoned mine shafts and adits with lightweight concrete

    International Nuclear Information System (INIS)

    Skinner, E.H.; Beckett, L.A.

    1994-01-01

    An abandoned mine shaft near Omar, in Logan County, WV, was permanently sealed through a cooperative agreement between the West Virginia Department of Commerce, Labor, and Environmental Resources, Division of Environmental Protection, and the US Bureau of Mines (USBM), Abandoned Mine Lands (AML) Program. An engineered shaft seal design was developed and demonstrated that featured lightweight concrete as a key material component at a wet density of about 45 lb/ft 3 . A reinforced concrete cap designed for 5 psi live load was placed over the shaft seal. Applicable new concrete technologies relating to a 100-yr design life were utilized to assure future integrity of the shaft seal. Waterproofing methods were included in the shaft seal design to provide protection from ambient moisture and corrosive mine waters and to increase the long-term durability of the shaft seal. All construction methods used in the field trial are fully adaptable for the mine-reclamation contractor. The USBM research objectives were to develop a broad generic design that will be widely applicable to other adit-sealing and shaft-sealing problems throughout the mining industry

  2. Prevalence of metabolic syndrome and its components based on a harmonious definition among adults in Morocco

    Directory of Open Access Journals (Sweden)

    El Brini O

    2014-07-01

    Full Text Available Otmane El Brini,1 Omar Akhouayri,1 Allal Gamal,2 Abdelhalem Mesfioui,1 Bouchra Benazzouz1 1Laboratory of Genetic, Neuroendocrinology and Biotechnology, University Ibn Tofail, Faculty of Sciences, Kenitra, Morocco; 2Diagnostic center, Rabat, Morocco Purpose: Metabolic syndrome is a cluster of risk factors for diabetes and cardiovascular diseases that includes central obesity, hypertension, glucose intolerance, high triglyceride, and low high-density lipoprotein cholesterol. Its prevalence is rapidly increasing worldwide. This study aimed to estimate the prevalence of the metabolic syndrome and associated risk factors in a representative sample of Morocco adults using the 2009 joint interim statement definition. Patients and methods: We analyzed data of 820 patients aged 19 years and older. For metabolic syndrome diagnosis, we used the criteria of the recently published joint interim statement (2009. Results: The prevalence of metabolic syndrome is 35.73% among all adults, 18.56% among men, and 40.12% among women. Prevalence increased with age, peaking among those aged 50–59 years. The most common abnormality highlights abdominal obesity (49.15%. Also, half of patients have one or two risk factors for developing this syndrome. Conclusion: The prevalence of metabolic syndrome and associated risk factors is high among adults in Morocco, especially in women. The most prevalent component of metabolic syndrome in our population was abdominal obesity. Keywords: central obesity, hypertension, glucose intolerance, triglyceride, cholesterol

  3. Scenario-based teaching in undergraduate medical education

    Directory of Open Access Journals (Sweden)

    Patel K

    2016-12-01

    Full Text Available Kunj Patel, Omar El Tokhy Faculty of Medicine, Imperial College London, London, UKWe read with great interest the study by Frost et al1 which highlights the importance of scenario-based teaching (SBT of clinical communication in medical undergraduate pediatrics teaching. SBT involves students navigating a storyline based around a complex problem, running in parallel with case-based learning. We were impressed by the results of the SBT program at Cardiff University School of Medicine. As medical students currently on our pediatric rotation at Imperial College London, we have experienced at first hand the benefits of SBT. Throughout the placement, it continues to help us tackle the complexities which arise when communicating with children and their families. We have noted its particular benefit in breaking bad news to families. Without effective teaching on this particular scenario, a failure to grasp this skill could exacerbate patient and parent concerns. Much like the authors of this study highlight,1 we believe specific teaching on communication skills should be a mandatory part of medical undergraduate education at every institution. Imperial College School of Medicine has developed a similar teaching style which has been unparalleled in its benefit to us during our pediatric rotation. Although there is scant literature available specifically addressing communicating with children and parents at undergraduate level, the use of SBT throughout undergraduate medical teaching should not be underestimated. Read the original paper by Frost et al

  4. Monthly streamflow forecasting with auto-regressive integrated moving average

    Science.gov (United States)

    Nasir, Najah; Samsudin, Ruhaidah; Shabri, Ani

    2017-09-01

    Forecasting of streamflow is one of the many ways that can contribute to better decision making for water resource management. The auto-regressive integrated moving average (ARIMA) model was selected in this research for monthly streamflow forecasting with enhancement made by pre-processing the data using singular spectrum analysis (SSA). This study also proposed an extension of the SSA technique to include a step where clustering was performed on the eigenvector pairs before reconstruction of the time series. The monthly streamflow data of Sungai Muda at Jeniang, Sungai Muda at Jambatan Syed Omar and Sungai Ketil at Kuala Pegang was gathered from the Department of Irrigation and Drainage Malaysia. A ratio of 9:1 was used to divide the data into training and testing sets. The ARIMA, SSA-ARIMA and Clustered SSA-ARIMA models were all developed in R software. Results from the proposed model are then compared to a conventional auto-regressive integrated moving average model using the root-mean-square error and mean absolute error values. It was found that the proposed model can outperform the conventional model.

  5. Turbidimeter Design and Analysis: A Review on Optical Fiber Sensors for the Measurement of Water Turbidity

    Science.gov (United States)

    Omar, Ahmad Fairuz Bin; MatJafri, Mohd Zubir Bin

    2009-01-01

    Turbidimeters operate based on the optical phenomena that occur when incident light through water body is scattered by the existence of foreign particles which are suspended within it. This review paper elaborates on the standards and factors that may influence the measurement of turbidity. The discussion also focuses on the optical fiber sensor technologies that have been applied within the lab and field environment and have been implemented in the measurement of water turbidity and concentration of particles. This paper also discusses and compares results from three different turbidimeter designs that use various optical components. Mohd Zubir and Bashah and Daraigan have introduced a design which has simple configurations. Omar and MatJafri, on the other hand, have established a new turbidimeter design that makes use of optical fiber cable as the light transferring medium. The application of fiber optic cable to the turbidimeter will present a flexible measurement technique, allowing measurements to be made online. Scattered light measurement through optical fiber cable requires a highly sensitive detector to interpret the scattered light signal. This has made the optical fiber system have higher sensitivity in measuring turbidity compared to the other two simple turbidimeters presented in this paper. Fiber optic sensors provide the potential for increased sensitivity over large concentration ranges. However, many challenges must be examined to develop sensors that can collect reliable turbidity measurements in situ. PMID:22408507

  6. Pulmonary hypertension and vasculopathy in incontinentia pigmenti: a case report

    Directory of Open Access Journals (Sweden)

    Alshenqiti A

    2017-05-01

    Full Text Available Abduljabbar Alshenqiti,1 Marwan Nashabat,1 Hissah AlGhoraibi,1 Omar Tamimi,2 Majid Alfadhel1 1Division of Genetics, Department of Pediatrics, King Abdullah International Medical Research Centre, King Saud bin Abdulaziz Uiversity for Health Sciences, King Abdulaziz Medical City, Ministry of National Guard Health Affairs (NGHA, Riyadh, Saudi Arabia; 2Department of Cardiology, King Abdullah International Medical Research Centre, King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs (NGHA, Riyadh, Saudi Arabia Abstract: Incontinentia pigmenti (IP; Bloch–Sulzberger syndrome is a rare, genetic syndrome inherited as an X-linked dominant trait. It primarily affects female infants and is lethal in the majority of males during fetal life. The clinical findings include skin lesions, developmental defects, and defects of the eyes, teeth, skeletal system, and central nervous system. Cardiovascular complications of this disease in general, and pulmonary hypertension in particular, are extremely rare. This report describes the case of a 3-year-old girl with IP complicated by pulmonary arterial hypertension. Extensive cardiology workup done to the patient indicates underlying vasculopathy. This report sheds light on the relationship between IP and pulmonary hypertension, reviews the previously reported cases, and compares them with the reported case. Keywords: incontinentia pigmenti, IKBKG, pulmonary hypertension, vasculopathy, Bloch–Sulzberger syndrome, lines of Blaschko, hyperpigmentation

  7. مقدمة كتاب توحيد المفضل (دراسة تداولية

    Directory of Open Access Journals (Sweden)

    مشكور حنون كاظم الطالقاني

    2017-05-01

    Full Text Available Researchers have studied the language a scientific study in order to content analysis and decoding and thereupon assumed her multiple approaches is that these approaches have produced different problematic prevented the achievement of the desired goal, and it followed other approaches restore the shrine to speak to the fold linguistic analysis was deliberative one of the most prominent of these approaches, they aware of the linguistic study of language use, or during use. In light of this study the introduction of the book came (unification preferred pragmatics study in order to be an arena for analysis pragmatics. This book includes a long talk of Imam Jafar Sadeq (AS which he addressed the topics: Kgmh and knowledge of God and the mysteries of creation. Was dictated by the favorite son of Omar Aljafee came, research titled (the preface to unify the preferred pragmatics study included three axes and pave the finale, which included the boot to a range of deliberative terminology and definition of the book, and the first axis dealt context communicative and elements of the President, while addressing the second axis former assumption, and the third axis devoted to talk about the theory of speech acts. Was reached that verbal acts and multiple different and described in terms of honesty and lying, and there is an exchange of words between the roles with respect to the speaker and receiver each of which has its own communicative context

  8. Modeling biogeochemical processes in sediments from the Rhône River prodelta area (NW Mediterranean Sea

    Directory of Open Access Journals (Sweden)

    L. Pastor

    2011-05-01

    Full Text Available In situ oxygen microprofiles, sediment organic carbon content, and pore-water concentrations of nitrate, ammonium, iron, manganese, and sulfides obtained in sediments from the Rhône River prodelta and its adjacent continental shelf were used to constrain a numerical diagenetic model. Results showed that (1 the organic matter from the Rhône River is composed of a fraction of fresh material associated to high first-order degradation rate constants (11–33 yr−1; (2 the burial efficiency (burial/input ratio in the Rhône prodelta (within 3 km of the river outlet can be up to 80 %, and decreases to ~20 % on the adjacent continental shelf 10–15 km further offshore; (3 there is a large contribution of anoxic processes to total mineralization in sediments near the river mouth, certainly due to large inputs of fresh organic material combined with high sedimentation rates; (4 diagenetic by-products originally produced during anoxic organic matter mineralization are almost entirely precipitated (>97 % and buried in the sediment, which leads to (5 a low contribution of the re-oxidation of reduced products to total oxygen consumption. Consequently, total carbon mineralization rates as based on oxygen consumption rates and using Redfield stoichiometry can be largely underestimated in such River-dominated Ocean Margins (RiOMar environments.

  9. Female genital mutilation of minors in Italy: is a harmless and symbolic alternative justified?

    Directory of Open Access Journals (Sweden)

    Maria Luisa Di Pietro

    2012-09-01

    Full Text Available

    In 2004, Omar Abdulcadir - a gynecologist of the Centre for the prevention and therapy of female genital mutilation (FMG at the Careggi Hospital (Florence - proposed a “harmless and symbolic” alternative to FMG, which consists in the puncture of the clitoris under local anesthesia, in order to allow the outflow of some drops of blood (1.

    The intention behind the symbolic alternative is to avoid more severe forms of FGM while respecting cultural heritage. The proposal of this alternative procedure, which was sustained by the leaders of 10 local African immigrant communities, has encountered ample criticism (1.

    However, the question is: is the puncture of the clitoris prohibited by the Italian Law n. 7/2006? If it is not, could it be considered a method of reducing health risks caused by the more invasive forms of FGM (2? Or could it culturally legitimize FGM, causing a greater difficulty in the attempts to prevent and eradicate FGM in Italy?

  10. Measuring reproductive tourism through an analysis of Indian ART clinic Websites

    Directory of Open Access Journals (Sweden)

    Deonandan R

    2012-09-01

    Full Text Available Raywat Deonandan, Mirhad Loncar, Prinon Rahman, Sabrina OmarInterdisciplinary School of Health Sciences, University of Ottawa, Ottawa, CanadaObjectives: India is fast becoming the most prominent player in the global industry of reproductive tourism, in which infertile people cross international borders to seek assisted reproduction technologies. This study was conducted to better understand the extent and manner in which Indian clinics seek foreign clients.Methods: A systematic search of official Indian assisted reproduction technologies clinic Websites was undertaken, and instances noted where foreign clients were overtly targeted, and where maternal surrogacy was overtly offered.Results: A total of 159 clinics with Web addresses were identified, though only 78 had functioning Websites. All were published in English, with the majority clustered in the states of Maharashtra (14 and Gujarat (9. Of the 78 functioning Websites, 53 (68% featured some mention of maternal surrogacy services, and 42 (54% made overt overtures to foreign clients. Qualitative appeals to foreigners included instructions for international adoption, visa application, and the legal parental disposition of the surrogate. All Maharashtran clinic Websites that mentioned surrogacy also overtly featured reproductive tourism. Preimplantation diagnosis services were not offered disproportionately by clinics mentioning reproductive tourism.Conclusions: Based upon clinic online profiles, reproductive tourism comprises a substantial fraction of India’s assisted reproduction technologies clinics’ business focus, clustering around its most tourist-friendly locales, and surrogacy may be a strong motivator for international clientele.Keywords: assisted reproduction, global health, social media, marketing, development, IVF, surrogacy, PGD

  11. Turbidimeter Design and Analysis: A Review on Optical Fiber Sensors for the Measurement of Water Turbidity

    Directory of Open Access Journals (Sweden)

    Mohd Zubir Bin MatJafri

    2009-10-01

    Full Text Available Turbidimeters operate based on the optical phenomena that occur when incident light through water body is scattered by the existence of foreign particles which are suspended within it. This review paper elaborates on the standards and factors that may influence the measurement of turbidity. The discussion also focuses on the optical fiber sensor technologies that have been applied within the lab and field environment and have been implemented in the measurement of water turbidity and concentration of particles. This paper also discusses and compares results from three different turbidimeter designs that use various optical components. Mohd Zubir and Bashah and Daraigan have introduced a design which has simple configurations. Omar and MatJafri, on the other hand, have established a new turbidimeter design that makes use of optical fiber cable as the light transferring medium. The application of fiber optic cable to the turbidimeter will present a flexible measurement technique, allowing measurements to be made online. Scattered light measurement through optical fiber cable requires a highly sensitive detector to interpret the scattered light signal. This has made the optical fiber system have higher sensitivity in measuring turbidity compared to the other two simple turbidimeters presented in this paper. Fiber optic sensors provide the potential for increased sensitivity over large concentration ranges. However, many challenges must be examined to develop sensors that can collect reliable turbidity measurements in situ.

  12. Analysis and Reduction of Complex Networks Under Uncertainty.

    Energy Technology Data Exchange (ETDEWEB)

    Ghanem, Roger G [University of Southern California

    2014-07-31

    This effort was a collaboration with Youssef Marzouk of MIT, Omar Knio of Duke University (at the time at Johns Hopkins University) and Habib Najm of Sandia National Laboratories. The objective of this effort was to develop the mathematical and algorithmic capacity to analyze complex networks under uncertainty. Of interest were chemical reaction networks and smart grid networks. The statements of work for USC focused on the development of stochastic reduced models for uncertain networks. The USC team was led by Professor Roger Ghanem and consisted of one graduate student and a postdoc. The contributions completed by the USC team consisted of 1) methodology and algorithms to address the eigenvalue problem, a problem of significance in the stability of networks under stochastic perturbations, 2) methodology and algorithms to characterize probability measures on graph structures with random flows. This is an important problem in characterizing random demand (encountered in smart grid) and random degradation (encountered in infrastructure systems), as well as modeling errors in Markov Chains (with ubiquitous relevance !). 3) methodology and algorithms for treating inequalities in uncertain systems. This is an important problem in the context of models for material failure and network flows under uncertainty where conditions of failure or flow are described in the form of inequalities between the state variables.

  13. A review on organic spintronic materials and devices: II. Magnetoresistance in organic spin valves and spin organic light emitting diodes

    Directory of Open Access Journals (Sweden)

    Rugang Geng

    2016-09-01

    Full Text Available In the preceding review paper, Paper I [Journal of Science: Advanced Materials and Devices 1 (2016 128–140], we showed the major experimental and theoretical studies on the first organic spintronic subject, namely organic magnetoresistance (OMAR in organic light emitting diodes (OLEDs. The topic has recently been of renewed interest as a result of a demonstration of the magneto-conductance (MC that exceeds 1000% at room temperature using a certain type of organic compounds and device operating condition. In this report, we will review two additional organic spintronic devices, namely organic spin valves (OSVs where only spin polarized holes exist to cause magnetoresistance (MR, and spin organic light emitting diodes (spin-OLEDs where both spin polarized holes and electrons are injected into the organic emissive layer to form a magneto-electroluminescence (MEL hysteretic loop. First, we outline the major advances in OSV studies for understanding the underlying physics of the spin transport mechanism in organic semiconductors (OSCs and the spin injection/detection at the organic/ferromagnet interface (spinterface. We also highlight some of outstanding challenges in this promising research field. Second, the first successful demonstration of spin-OLEDs is reviewed. We also discuss challenges to achieve the high performance devices. Finally, we suggest an outlook on the future of organic spintronics by using organic single crystals and aligned polymers for the spin transport layer, and a self-assembled monolayer to achieve more controllability for the spinterface.

  14. Light-induced magnetoresistance in solution-processed planar hybrid devices measured under ambient conditions

    Directory of Open Access Journals (Sweden)

    Sreetama Banerjee

    2017-07-01

    Full Text Available We report light-induced negative organic magnetoresistance (OMAR measured in ambient atmosphere in solution-processed 6,13-bis(triisopropylsilylethynylpentacene (TIPS-pentacene planar hybrid devices with two different device architectures. Hybrid electronic devices with trench-isolated electrodes (HED-TIE having a channel length of ca. 100 nm fabricated in this work and, for comparison, commercially available pre-structured organic field-effect transistor (OFET substrates with a channel length of 20 µm were used. The magnitude of the photocurrent as well as the magnetoresistance was found to be higher for the HED-TIE devices because of the much smaller channel length of these devices compared to the OFETs. We attribute the observed light-induced negative magnetoresistance in TIPS-pentacene to the presence of electron–hole pairs under illumination as the magnetoresistive effect scales with the photocurrent. The magnetoresistance effect was found to diminish over time under ambient conditions compared to a freshly prepared sample. We propose that the much faster degradation of the magnetoresistance effect as compared to the photocurrent was due to the incorporation of water molecules in the TIPS-pentacene film.

  15. Sonomammographic characteristics of invasive lobular carcinoma

    Directory of Open Access Journals (Sweden)

    El-Damshety O

    2012-07-01

    Full Text Available Osama R Kombar,1,3 Dalia M Fahmy,1 Mary V Brown,3 Omar Farouk,2 Osama El-Damshety21Diagnostic Radiology Department, 2Surgical Oncology Department, Oncology Center, Mansoura University, Mansoura, Egypt; 3Diagnostic Radiology Department, Al-Amiri Hospital, Safat, KuwaitObjective: The objective of our study was to identify characteristic features of invasive lobular carcinoma on mammography and ultrasound examinationsMaterials and methods: This is a retrospective multicenter study of women with biopsy-proven invasive lobular carcinoma. All patients had undergone diagnostic sonomammography. The imaging findings were identified by experienced breast imagers. Final surgical pathology results were used as the reference standard.Results: Thirty-two women ranging in age from 42 to 63 years old (mean age, 53 years, All had biopsy-proven invasive lobular carcinomas. Common features on mammogram included dense mass followed by architectural distortion; three cases showed breast asymmetry and one case was reported as normal. On ultrasound, common features included solid mass with spiculated margins, posterior shadowing, and perpendicular to the skin.Conclusion: Although no specific features could be linked to invasive lobular carcinoma, care should be directed to subtle signs such as architectural distortion and breast asymmetry in order not to miss any lesions. The combination of mammographic and sonographic helps to decrease the relatively high false negative diagnosis of this type of breast cancer.Keywords: mammography, ultrasound, cancer, breast

  16. Efficacy and safety of fentanyl buccal for cancer pain management by administration through a soluble film: an update

    Directory of Open Access Journals (Sweden)

    Marvin Omar Delgado-Guay

    2010-11-01

    Full Text Available Marvin Omar Delgado-GuayDivision of Geriatrics and Palliative Medicine, The University of Texas, Medical School at Houston, Houston, TX, USAAbstract: More than half of patients receiving prescription medicine for cancer pain have been reported to experience inadequate pain relief or breakthrough pain. Buccal administration can deliver lipophilic opioids rapidly to the systemic circulation through the buccal mucosa, limiting gastrointestinal motility and first-pass metabolism. This review updates the safety and efficacy of fentanyl buccal soluble film (FBSF in patients with cancer pain. Literature was identified through searches of Medline (PubMed. Search terms included combinations of the following: cancer pain, fentanyl, fentanyl buccal soluble film, pharmacology, kinetics, safety, efficacy and toxicity. FBSF is an oral transmucosal form of fentanyl citrate developed as a treatment of breakthrough pain in opioid-tolerant patients with cancer. Studies have shown that it is well tolerated in the oral cavity, with adequate bioavailability and safety in cancer patients. Further studies are warranted to evaluate, in comparison with other short-acting opioids, its efficacy in the management of breakthrough cancer pain, its addictive potential and its economic impact in cancer patients.Keywords: fentanyl buccal soluble film, cancer pain

  17. Prevalence of Electrolyte Disorders Among Cases of Diarrhea with Severe Dehydration and Correlation of Electrolyte Levels with Age of the Patients

    International Nuclear Information System (INIS)

    Ahmad, M. S.; Wahid, A.; Ahmad, M.; Mahboob, N.; Mehmood, R.

    2016-01-01

    Objective: To find out the prevalence of electrolyte disorders among children with severe dehydration, and to study correlation between age and electrolyte, urea and creatinine levels. Study Design: Prospective, analytical study. Place and Duration of Study: Outdoor and indoor of Fazle-Omar Hospital, Rabwah, Pakistan, from January to December 2012. Methodology: All patients from birth to 18 years age, presenting with diarrhea and severe dehydration were included in the study. Urea, creatinine and electrolyte levels of all patients included in the study were checked and recorded in the data form with name, age and outcome. The prevalence of electrolyte disorders were ascertained and correlation with age was determined by Pearson's coefficient. Result: At total of 104 patients were included in the study. None of the patients died. Hyperchloremia was the commonest electrolyte disorder (53.8 percentage), followed by hyperkalemia (26.9 percentage) and hypernatremia (17.3 percentage). Hyponatremia, hypokalemia and hypochloremia were present in 10.6 percentage, 7.7 percentage, and 10.6 percentage cases, respectively. Weak negative correlation was found between age and chloride and potassium levels. Conclusion: Different electrolyte disorders are common in children with diarrhea-related severe dehydration. (author)

  18. Prevalence of Electrolyte Disorders Among Cases of Diarrhea with Severe Dehydration and Correlation of Electrolyte Levels with Age of the Patients.

    Science.gov (United States)

    Ahmad, Mirza Sultan; Wahid, Abdul; Ahmad, Mubashra; Mahboob, Nazia; Mehmood, Ramlah

    2016-05-01

    To find out the prevalence of electrolyte disorders among children with severe dehydration, and to study correlation between age and electrolyte, urea and creatinine levels. Prospective, analytical study. Outdoor and indoor of Fazle-Omar Hospital, Rabwah, Pakistan, from January to December 2012. All patients from birth to 18 years age, presenting with diarrhea and severe dehydration were included in the study. Urea, creatinine and electrolyte levels of all patients included in the study were checked and recorded in the data form with name, age and outcome. The prevalence of electrolyte disorders were ascertained and correlation with age was determined by Pearson's coefficient. At total of 104 patients were included in the study. None of the patients died. Hyperchloremia was the commonest electrolyte disorder (53.8%), followed by hyperkalemia (26.9%) and hypernatremia (17.3%). Hyponatremia, hypokalemia and hypochloremia were present in 10.6%, 7.7%, and 10.6% cases, respectively. Weak negative correlation was found between age and chloride and potassium levels. Different electrolyte disorders are common in children with diarrhea-related severe dehydration.

  19. Streptococcus pneumoniae sepsis as the initial presentation of systemic lupus erythematosus

    Directory of Open Access Journals (Sweden)

    Erdem I

    2016-09-01

    Full Text Available Ilknur Erdem,1 Senay Elbasan Omar,1 Ridvan Kara Ali,1 Hayati Gunes,2 Aynur Eren Topkaya2 1Department of Infectious Diseases, 2Department of Medical Microbiology, Faculty of Medicine, Namik Kemal University, Tekirdag, Turkey Objective: Infections are among the most important causes of morbidity and mortality in patients with systemic lupus erythematosus (SLE but are rare initial presentation of the disease. Therefore, in this study, we describe a case of Streptococcus pneumoniae sepsis in a young woman with previously undiagnosed SLE. Case report: A 23-year-old female patient was admitted to our outpatient clinic complaining of high fever (40°C, chills, fatigue, generalized myalgia, and cough with brown sputum for 5 days. Blood cultures grew gram-positive coccus defined as S. pneumoniae using standard procedures. Antinuclear antibody was positive at a titer of 1/1,000, and anti-double-stranded DNA was positive at 984 IU/mL. She was diagnosed with SLE. Her respiratory symptoms and pleural effusion were considered to be due to pulmonary manifestation of SLE. Conclusion: The underlying immunosuppression caused by SLE could have predisposed the patient to invasive pneumococcal disease. It may also occur as a primary presenting feature, although a rare condition. Keywords: Streptococcus pneumoniae, sepsis, systemic lupus erythematosus

  20. El relato de la memoria en el teatro de Buenos Aires

    Directory of Open Access Journals (Sweden)

    Silvina Díaz

    2016-07-01

    Full Text Available La recuperación de la memoria y el testimonio se han convertido en un requerimiento vital luego de la más cruenta dictadura militar argentina, que tuvo lugar entre 1976 y 1983. Los traumas históricos acarreados y las profundas heridas, individuales y colectivas, dieron lugar a innumerables hechos culturales. Nos proponemos analizar dos modos diversos, dentro de la dramaturgia de la posdictadura, de narrar la problemática de la represión y los desaparecidos, como paradigmas de toda una tendencia de textos que consideran al teatro como un instrumento de indagación social y política. La obra de Lola Arias recurre a un lenguaje referencial y explícito –propio del teatro político–, aun cuando contenga una importante carga simbólica, mientras que los textos de Omar Pacheco manifiestan la crisis del relato dramático tradicional y de la noción restrictiva que considera a la palabra únicamente en su dimensión psicologista y semántica, para destacar en cambio su materialidad y su opacidad sígnica.

  1. A case of probable esomeprazole-induced transient liver injury in a pregnant woman with hyperemesis

    Directory of Open Access Journals (Sweden)

    Thomas B

    2016-12-01

    Full Text Available Binny Thomas,1-3 Mahmoud Mohamed,1,3,4 Moza Al Hail,1-3 Fatma Alzahra Y Awwad,1 Ramy M Wahba,1 Sabir B Hassan,1 Khalid Omar,1 Wessam El Kassem,1 Palivalappila Abdul Rouf1 1Hamad Medical Corporation, Doha, Qatar; 2Robert Gordon University, Aberdeen, Scotland, UK; 3Qatar University, Doha, 4Weill Cornell Medical College, Ar-Rayyan, Qatar Abstract: We report a case of 22-year-old primigravida presented to Women’s Hospital – Hamad Medical Corporation emergency with severe epigastric pain, nausea, and vomiting. On admission, she was dehydrated with remarkably worsening symptoms. Laboratory findings revealed significantly elevated liver enzymes with unknown etiology. Her past medical history showed an admission for nausea and vomiting 3 weeks previously and she was discharged on antiemetics, and esomeprazole for the first time. Due to the predominantly elevated liver enzymes, the clinical pharmacist discussed the possibility of esomeprazole-induced adverse effects and suggested to suspend esomeprazole based on the evidence from literature review. The liver enzymes showed a substantial improvement within days after the discontinuation of the drug; however, a rechallenge was not done since it could have adversely affected the mother or the fetus. Using the Naranjo Adverse Drug Reaction Probability scales, the adverse reaction due to esomeprazole was classified as “probably”. Keywords: hyperemesis, drug-induced liver injury, esomeprazole, adverse drug reaction, ADR, proton pump inhibitor

  2. Acid phosphatase patterns in microfilariae of Onchocerca volvulus s.l. from the Upper Orinoco Basin, Venezuela.

    Science.gov (United States)

    Yarzàbal, L; Petralanda, I; Arango, M; Lobo, L; Botto, C

    1983-06-01

    The patterns of acid phosphatase in strains of Onchocerca volvulus s.l. which parasitize an Amerindian population (Yanomami) in Venezuela's Upper Orinoco Basin were examined by using the naphthol AS-TR phosphate method. The study sample consisted of 40 Yanomami inhabiting a savannah area at 950 m above sea level and 21 Yanomami residents of a tropical rainforest area at an altitude of 250 m. Stained intrauterine microfilariae, still within the egg case, exhibited a diffuse distribution of the enzyme in the early stages of embryonic development and a negative reaction at a more developed stage. Four of the five enzyme staining patterns described by Omar (1978) were found in the 3157 microfilariae examined from skin snips. Their distribution was: Type I--17.2%, Type III--0.5%, Type IV--75.6% and Type V--6.6%. No examples of Type II were observed. The results indicate that acid phosphatase patterns of the Upper Orinoco Onchocerca strain most resemble those of strains from Guatemala and Yemen, and are different from the African strains found in Upper Volta and Liberia. The relative frequency of acid phosphatase patterns was modified by cryopreservation of microfilariae.

  3. Implementación a nivel universitario del curso INTEL educar para el futuro: sistematización de la experiencia en la Facultad de Educación de la Universidad de Costa Rica

    Directory of Open Access Journals (Sweden)

    Flora Eugenia Salas Madriz

    2003-01-01

    Full Text Available La Facultad de Educación de la Universidad de Costa Rica, consciente del impacto e importancia que están adquiriendo las tecnologías educativas digitales en el ámbito educativo a nivel nacional y mundial, ha creado el Programa Tecnologías Educativas Avanzadas (PROTEA para el desarrollo y la investigación en este campo. En este artículo se sistematiza la experiencia de nueve docentes de la Universidad de Costa Rica, que colaboraron en la adecuación para el nivel universitario del curso Intel Educar para el Futuro, impartido por la Fundación Omar Dengo. Éste está orientado a educadores de primaria y secundaria, y su propósito es poner a disposición de los educadores las herramientas del Office® de Microsoft ® para desarrollar los procesos de enseñanza. Debido a las diferencias de fondo y forma entre la educación primaria y secundaria, y la universitaria, se hizo necesario revisar el manual y la metodología a fin de adaptarlos a las necesidades de la docencia universitaria y de la formación de formadores. En este sentido, la experiencia y colaboración de los docentes participantes fue determinante para lograr que el curso alcance hoy sus objetivos de poner estas herramientas al servicio de la docencia universitaria

  4. Storie ‘vere’ ed eroine dei romanzi. Rappresentare la Somalia in 'Ilaria Alpi. La ragazza che voleva raccontare l’inferno' e 'Non dirmi che hai paura'

    Directory of Open Access Journals (Sweden)

    Simone Brioni

    2016-09-01

    Full Text Available ‘True’ Stories and Heroines in Novels: The Representation of Somalia in Ilaria Alpi: The Young Woman Who Wanted to Narrate Hell and Don’t Tell Me You Are AfraidThis article analyses Gigliola Alvisi’s Ilaria Alpi: La ragazza che voleva raccontare l’inferno [Ilaria Alpi: The Young Woman Who Wanted to Narrate the Hell] (2014 and Giuseppe Catozzella’s Non dirmi che hai paura [Don’t Tell Me You Are Afraid] (2014, two novels that deal with two recent events in Somali and Italian history, the killing of the journalist Ilaria Alpi in Mogadishu in 1994 and the death of Samia Yosuf Omar while she was trying to reach the Italian shores from Libya by boat. Alvisi’s text is analysed in comparison with other fictional and journalistic representations of Ilaria Alpi, while Non dirmi che hai paura is examined through what Catozzella considers the two constitutive dimensions of the novel: documentation and identification. Drawing on Stefano Jossa’s reflections on the construction of literary heroes, the article challenges Alvisi’s and Catozzella’s claims that they represent ‘true stories’. The article also argues that the main characters of these literary works are portrayed as heroines and role models for the emancipation of Muslim women.

  5. Light-induced magnetoresistance in solution-processed planar hybrid devices measured under ambient conditions.

    Science.gov (United States)

    Banerjee, Sreetama; Bülz, Daniel; Reuter, Danny; Hiller, Karla; Zahn, Dietrich R T; Salvan, Georgeta

    2017-01-01

    We report light-induced negative organic magnetoresistance (OMAR) measured in ambient atmosphere in solution-processed 6,13-bis(triisopropylsilylethynyl)pentacene (TIPS-pentacene) planar hybrid devices with two different device architectures. Hybrid electronic devices with trench-isolated electrodes (HED-TIE) having a channel length of ca. 100 nm fabricated in this work and, for comparison, commercially available pre-structured organic field-effect transistor (OFET) substrates with a channel length of 20 µm were used. The magnitude of the photocurrent as well as the magnetoresistance was found to be higher for the HED-TIE devices because of the much smaller channel length of these devices compared to the OFETs. We attribute the observed light-induced negative magnetoresistance in TIPS-pentacene to the presence of electron-hole pairs under illumination as the magnetoresistive effect scales with the photocurrent. The magnetoresistance effect was found to diminish over time under ambient conditions compared to a freshly prepared sample. We propose that the much faster degradation of the magnetoresistance effect as compared to the photocurrent was due to the incorporation of water molecules in the TIPS-pentacene film.

  6. Cuerpo extraño del bronquio derecho

    Directory of Open Access Journals (Sweden)

    José G. Ferreira

    1938-07-01

    Full Text Available EI menor Omar Villegas, natural de Manizales, residente actualmente en Puerto Tejada se le fue un alfiler de seguridad que tenía en la boca, al sacarse la camisa por encuna de los hombros. Tomada la primera radiografía, cuya copia y reducción le envío, el alfiler se encontraba en la tráquea a poca distancia de las cuerdas vocales. Al introducir el Broncoscopio, fue a alojarse al Bronquio derecho, sin duda por una fuerte inspiración, como se ve en la segunda Radiografía, cuyas copias y reducción también le envío. Ocho días después de la primera, hice la segunda Broncoscopía, con completo éxito, Por carecer de la pinza para cerrar los imperdibles, seguí la técnica indicada por el Profesor Chevalier Jackson, enorme experto sobre la materia. De manera que mi actuación se limitó, a asir el alfiler por su punta para montarlo sobre el Broncoscopio o sacarlo por el tubo, cosa esta última, que fue la que hice, por permitirlo su tamaño.

  7. The Wire and the Disenchantment of the Outsider

    DEFF Research Database (Denmark)

    Jensen, Mikkel Bo Brendstrup

    2019-01-01

    for themselves but in the analysis of selected characters from the show – Omar Little, Jimmy McNulty, and Stringer Bell – it is shown that these characters all are outsiders in different ways and that the show tries to debunk the charisma of the outsider that relates to these characters. This deromanticization......This article presents a contextualist reading of the television serial The Wire (2002-2008). Drawing on Grace Hale’s A Nation of Outsiders (2011), the article argues that there is a tension between this show and its paratexts in the way that the creators of the show embrace an outsider rhetoric...... of the outsider is an important part of the politics that the show espouses and the article argues that this rejection is a part of the show’s “sociological gaze” where all social phenomena are seen in relation to each other and the The Wire is shown not to buy into the notion of a free space beyond...

  8. Identification and genomic characterization of a novel porcine parvovirus (PPV6) in China.

    Science.gov (United States)

    Ni, Jianqiang; Qiao, Caixia; Han, Xue; Han, Tao; Kang, Wenhua; Zi, Zhanchao; Cao, Zhen; Zhai, Xinyan; Cai, Xuepeng

    2014-12-02

    Parvoviruses are classified into two subfamilies based on their host range: the Parvovirinae, which infect vertebrates, and the Densovirinae, which mainly infect insects and other arthropods. In recent years, a number of novel parvoviruses belonging to the subfamily Parvovirinae have been identified from various animal species and humans, including human parvovirus 4 (PARV4), porcine hokovirus, ovine partetravirus, porcine parvovirus 4 (PPV4), and porcine parvovirus 5 (PPV5). Using sequence-independent single primer amplification (SISPA), a novel parvovirus within the subfamily Parvovirinae that was distinct from any known parvoviruses was identified and five full-length genome sequences were determined and analyzed. A novel porcine parvovirus, provisionally named PPV6, was initially identified from aborted pig fetuses in China. Retrospective studies revealed the prevalence of PPV6 in aborted pig fetuses and piglets(50% and 75%, respectively) was apparently higher than that in finishing pigs and sows (15.6% and 3.8% respectively). Furthermore, the prevalence of PPV6 in finishing pig was similar in affected and unaffected farms (i.e. 16.7% vs. 13.6%-21.7%). This finding indicates that animal age, perhaps due to increased innate immune resistance, strongly influences the level of PPV6 viremia. Complete genome sequencing and multiple alignments have shown that the nearly full-length genome sequences were approximately 6,100 nucleotides in length and shared 20.5%-42.6% DNA sequence identity with other members of the Parvovirinae subfamily. Phylogenetic analysis showed that PPV6 was significantly distinct from other known parvoviruses and was most closely related to PPV4. Our findings and review of published parvovirus sequences suggested that a novel porcine parvovirus is currently circulating in China and might be classified into the novel genus Copiparvovirus within the subfamily Parvovirinae. However, the clinical manifestations of PPV6 are still unknown in that the

  9. First identification of porcine parvovirus 6 in North America by viral metagenomic sequencing of serum from pigs infected with porcine reproductive and respiratory syndrome virus.

    Science.gov (United States)

    Schirtzinger, Erin E; Suddith, Andrew W; Hause, Benjamin M; Hesse, Richard A

    2015-10-16

    Currently, eight species in four genera of parvovirus have been described that infect swine. These include ungulate protoparvovirus 1 (classical porcine parvovirus, PPV), ungulate tetraparvovirus 2 (PPV3), ungulate tetraparvovirus 3 (which includes PPV2, porcine hokovirus, porcine partetravirus and porcine PARV4), ungulate copiparvovirus 2 (which includes PPV4 and PPV5), ungulate bocaparvovirus 2 (which includes porcine bocavirus 1, 2 and 6), ungulate bocaparvovirus 3 (porcine bocavirus 5), ungulate bocaparvovirus 4 (porcine bocavirus 7) and ungulate bocaparvovirus 5 (porcine bocavirus 3, 4-1 and 4-2). PPV6, the most recently described porcine parvovirus, was first identified in China in late 2014 in aborted pig fetuses. Prevalence of PPV6 in China was found to be similar in finishing age pigs from farms with and without evidence of swine reproductive failure. Porcine parvovirus 6 (PPV6) was detected by sequence-independent single primer amplification (SISPA) and confirmed by overlapping and real-time PCR in the serum of porcine reproductive and respiratory virus (PRRSv) positive samples. Seven nearly complete genomes of PPV6 were identified in PRRSv genotype 2 positive serum samples submitted to state veterinary diagnostic laboratories in 2014. Further testing using overlapping and real-time PCR determined PPV6 to be present in 13.2 % of the serums tested. Additionally, PPV6 was present in samples from all of the geographic locations sampled encompassing nine states in the United States and one state in Mexico. The presence of PPV6 in serum indicates that the PPV6 infection is disseminated and not localized to a specific tissue type. Alignments of the near full length genomes, NS1, and capsid genes identified one of the five PPV6 isolates from China (98.6-99.5 % identity with the North American strains) to be the North American strains nearest relative. These results are the first to report the presence of PPV6 in North America and demonstrate that the virus is

  10. Lasteaia ja lõbumaja vahel : eesti proosa 2008 / Vaapo Vaher

    Index Scriptorium Estoniae

    Vaher, Vaapo, 1945-

    2009-01-01

    Ülevaade 2008. aasta eesti proosast. Pikemalt käsitletakse järgmisi autoreid ja nende teoseid: Mihkel Raud "Musta pori näkku", Olev Remsu "Musketäride muundumised", Rein Põder "Juba olnud", Juhan Nurme "Ligimene", Jaan Tangsoo "Méduse'i parv", Esta Aksli "Tare poole tõttaja", Mari Saat "Lasnamäe lunastaja", Peeter Morgen "Sõnum", Mait Raun "Dr. Mööbi seiklused Inglismaal", Andrei Hvostov "Võõrad lood" ja "Projektijuht Posse", Chaneldior "Kontrolli alt väljas", Vahur Afanasjev "Kosmos", Egon Ilisson "Isased", Jaak Leer "Kaks kabanossi ja Maaja", Kärt Hellerma "Sinine missa", Elo Viiding "Püha Maama", Toomas Raudam "Miks ma ei taha olla kirjanik?", Mart Kivastik "Kurb raamat", Jüri Tuulik "Räim, pisike kena kala", Tarmo Teder "12 jõulujuttu", Dagmar Lamp (koostaja) "Tule, ma jutustan sulle loo", Eia Uus "Kahe näoga jumal", Barthol Lo Mejor "Popdada 2007-2008", Anti Saar "Nemad kaks", Ketlin Priilinn "Liiseli võti" ja "Vaim", Aita Kivi "Lähedal", Marje Ernits "Hoia mu kätt", Kati Murutar "Naisena sündinud : kakskümmend aastat hiljem", Tuule Lind "Pööratud tuul", Siiri Laidla "Lihtne lugu, ehk, Senta suvepuhkus", Kätlin Padesaar "Veel üks paradiis", Aimée Beekman "Proovielu", Lehte Hainslau "Kolmkõla, ehk, 3 kõla", Ira Lember "Ööviiulid", Tamur Kusnets "Hundipäikese aeg : metsiku jahi algus", Kaupo Pähkel "Ehatähe rüütel", Arvo Valton "Ülemiste vanake", Tiit Aleksejev "Palveränd", Ants Eret "Afgaanide vang", Mario Merirand "Afganistani päevik", Leo Kunnas "Gort Ashryn", Rein Raud "Vend", Peeter Sauter "Beibi bluu", Marion Andra "Pimend", Kristjan Sander "13 talvist hetke", Helga Nõu "Peaaegu geenius, ehk, Schrödingeri kassi otsimas", Tiit Sepa "Eefa hüüdnimega Siug", Kaarel ja Klaara Kivi "Varandus seinal", Merike Jürjo "Mälestusteta maja", Rein Vahisalu "Viies kabinet", Aarne Biin "Mees otsib naist", Erik Tohvri "Ümberasujad" ja "Sulasest sai peremees", Arnold Laugus "Elav maa", Jüri v. Grauberg "Selguse poole", J

  11. Lasteaia ja lõbumaja vahel : Eesti proosa 2008 / Vaapo Vaher

    Index Scriptorium Estoniae

    Vaher, Vaapo, 1945-

    2012-01-01

    Ülevaade 2008. aasta eesti proosast. Pikemalt käsitletakse järgmisi autoreid ja nende teoseid: Mihkel Raud "Musta pori näkku", Olev Remsu "Musketäride muundumised", Rein Põder "Juba olnud", Juhan Nurme "Ligimene", Jaan Tangsoo "Méduse'i parv", Esta Aksli "Tare poole tõttaja", Mari Saat "Lasnamäe lunastaja", Peeter Morgen "Sõnum", Mait Raun "Dr. Mööbi seiklused Inglismaal", Andrei Hvostov "Võõrad lood" ja "Projektijuht Posse", Chaneldior "Kontrolli alt väljas", Vahur Afanasjev "Kosmos", Egon Ilisson "Isased", Jaak Leer "Kaks kabanossi ja Maaja", Kärt Hellerma "Sinine missa", Elo Viiding "Püha Maama", Toomas Raudam "Miks ma ei taha olla kirjanik?", Mart Kivastik "Kurb raamat", Jüri Tuulik "Räim, pisike kena kala", Tarmo Teder "12 jõulujuttu", Dagmar Lamp (koostaja) "Tule, ma jutustan sulle loo", Eia Uus "Kahe näoga jumal", Barthol Lo Mejor "Popdada 2007-2008", Anti Saar "Nemad kaks", Ketlin Priilinn "Liiseli võti" ja "Vaim", Aita Kivi "Lähedal", Marje Ernits "Hoia mu kätt", Kati Murutar "Naisena sündinud : kakskümmend aastat hiljem", Tuule Lind "Pööratud tuul", Siiri Laidla "Lihtne lugu, ehk, Senta suvepuhkus", Kätlin Padesaar "Veel üks paradiis", Aimée Beekman "Proovielu", Lehte Hainslau "Kolmkõla, ehk, 3 kõla", Ira Lember "Ööviiulid", Tamur Kusnets "Hundipäikese aeg : metsiku jahi algus", Kaupo Pähkel "Ehatähe rüütel", Arvo Valton "Ülemiste vanake", Tiit Aleksejev "Palveränd", Ants Eret "Afgaanide vang", Mario Merirand "Afganistani päevik", Leo Kunnas "Gort Ashryn", Rein Raud "Vend", Peeter Sauter "Beibi bluu", Marion Andra "Pimend", Kristjan Sander "13 talvist hetke", Helga Nõu "Peaaegu geenius, ehk, Schrödingeri kassi otsimas", Tiit Sepa "Eefa hüüdnimega Siug", Kaarel ja Klaara Kivi "Varandus seinal", Merike Jürjo "Mälestusteta maja", Rein Vahisalu "Viies kabinet", Aarne Biin "Mees otsib naist", Erik Tohvri "Ümberasujad" ja "Sulasest sai peremees", Arnold Laugus "Elav maa", Jüri v. Grauberg "Selguse poole", J

  12. Genetic activation, inactivation and deletion reveal a limited and nuanced role for somatostatin-containing basal forebrain neurons in behavioral state control.

    Science.gov (United States)

    Anaclet, Christelle; De Luca, Roberto; Venner, Anne; Malyshevskaya, Olga; Lazarus, Michael; Arrigoni, Elda; Fuller, Patrick M

    2018-05-07

    Recent studies have identified an especially important role for basal forebrain GABAergic (BF VGAT ) neurons in the regulation of behavioral waking and fast cortical rhythms associated with cognition. However, BF VGAT neurons comprise several neurochemically and anatomically distinct sub-populations, including parvalbumin- and somatostatin-containing BF VGAT neurons (BF Parv and BF SOM ), and it was recently reported that optogenetic activation of BF SOM neurons increases the probability of a wakefulness to non-rapid-eye movement (NREM) sleep transition when stimulated during the animal's rest period. This finding was unexpected given that most BF SOM neurons are not NREM sleep active and that central administration of the synthetic SOM analog, octreotide, suppresses NREM sleep or increases REM sleep. Here we employed a combination of genetically-driven chemogenetic and optogenetic activation, chemogenetic inhibition and ablation approaches to further explore the in vivo role of BF SOM neurons in arousal control. Our findings indicate that acute activation or inhibition of BF SOM neurons is neither wakefulness- nor NREM sleep-promoting, is without significant effect on the EEG, and that chronic loss of these neurons is without effect on total 24h sleep amounts, although a small but significant increase in waking was observed in the lesioned mice during the early active period. Our in vitro cell recordings further reveal electrophysiological heterogeneity in BF SOM neurons, specifically suggesting at least two distinct sub-populations. Taken together our data support the more nuanced view that BF SOM are electrically heterogeneous and are not NREM sleep- or wake-promoting per se , but may exert, in particular during the early active period, a modest inhibitory influence on arousal circuitry. SIGNIFICANCE STATEMENT The cellular basal forebrain (BF) is a highly complex area of the brain that is implicated in a wide-range of higher-level neurobiological processes

  13. Conserved B-cell epitopes among human bocavirus species indicate potential diagnostic targets.

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    Zhuo Zhou

    Full Text Available BACKGROUND: Human bocavirus species 1-4 (HBoV1-4 have been associated with respiratory and enteric infections in children. However, the immunological mechanisms in response to HBoV infections are not fully understood. Though previous studies have shown cross-reactivities between HBoV species, the epitopes responsible for this phenomenon remain unknown. In this study, we used genomic and immunologic approaches to identify the reactive epitopes conserved across multiple HBoV species and explored their potential as the basis of a novel diagnostic test for HBoVs. METHODOLOGY/PRINCIPAL FINDINGS: We generated HBoV1-3 VP2 gene fragment phage display libraries (GFPDLs and used these libraries to analyze mouse antisera against VP2 protein of HBoV1, 2, and 3, and human sera positive for HBoVs. Using this approach, we mapped four epitope clusters of HBoVs and identified two immunodominant peptides--P1 (¹MSDTDIQDQQPDTVDAPQNT²⁰, and P2 (¹⁶²EHAYPNASHPWDEDVMPDL¹⁸⁰--that are conserved among HBoV1-4. To confirm epitope immunogenicity, we immunized mice with the immunodominant P1 and P2 peptides identified in our screen and found that they elicited high titer antibodies in mice. These two antibodies could only recognize the VP2 of HBoV 1-4 in Western blot assays, rather than those of the two other parvoviruses human parvovirus B19 and human parvovirus 4 (PARV4. Based on our findings, we evaluated epitope-based peptide-IgM ELISAs as potential diagnostic tools for HBoVs IgM antibodies. We found that the P1+P2-IgM ELISA showed a higher sensitivity and specificity in HBoVs IgM detection than the assays using a single peptide. CONCLUSIONS/SIGNIFICANCE: The identification of the conserved B-cell epitopes among human bocavirus species contributes to our understanding of immunological cross-reactivities of HBoVs, and provides important insights for the development of HBoV diagnostic tools.

  14. Meeting Report: 2013 PDA Virus & TSE Safety Forum.

    Science.gov (United States)

    Willkommen, Hannelore; Blümel, Johannes; Brorson, Kurt; Chen, Dayue; Chen, Qi; Gröner, Albrecht; Hubbard, Brian R; Kreil, Thomas R; Ruffing, Michel; Ruiz, Sol; Scott, Dorothy; Silvester, Glenda

    2014-01-01

    The report provides a summary of the presentations and discussions at the Virus & TSE Safety Forum 2013 organized by the Parenteral Drug Association (PDA) and held in Berlin, Germany, from June 4 to 6, 2013. The conference was accompanied by a workshop, "Virus Spike Preparations and Virus Removal by Filtration: New Trends and Developments". The presentations and the discussion at the workshop are summarized in a separate report that will be published in this issue of the journal as well. As with previous conferences of this series, the PDA Virus & TSE Safety Forum 2013 provided again an excellent opportunity to exchange information and opinions between the industry, research organizations, and regulatory bodies. Updates on regulatory considerations related to virus and transmissible spongiform encephalopathy (TSE) safety of biopharmaceuticals were provided by agencies of the European Union (EU), the United States (US), and Singapore. The epidemiology and detection methods of new emerging pathogens like hepatitis E virus and parvovirus (PARV 4) were exemplified, and the risk of contamination of animal-derived raw materials like trypsin was considered in particular. The benefit of using new sequence-based virus detection methods was discussed. Events of bioreactor contaminations in the past drew the attention to root cause investigations and preventive actions, which were illustrated by several examples. Virus clearance data of specific unit operations were provided; the discussion focused on the mechanism of virus clearance and on the strategic concept of viral clearance integration. As in previous years, the virus safety section was followed by a TSE section that covered recent scientific findings that may influence the risk assessment of blood and cell substrates. These included the realization that interspecies transmission of TSE by blood components in sheep is greater than predicted by assays in transgenic mice. Also, the pathogenesis and possibility of

  15. Valikuid ja võimalusi: ülevaade Uku Masingu luuletõlkimisest. Choices and possibilities: A survey of Uku Masing’s poetry translations

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    Aile Tooming

    2012-06-01

    Full Text Available This article gives a survey of the emblematic Estonian poet, theologian and scholar Uku Masing’s (1909– 1985 known poetry translations. The object is not a poetics of translation or an analysis of language, but an overview of the texts of poetry Masing translated: the time of publication, political influences on publishing, and the public reception or the lack of it. The focus is on the choices and interests of Masing as a translator, as well as the influence of society on which texts he translated. Masing started translating in the 1920s; by the end of the 1930s, he was known both as a theologian and poet, as well as a translator. Just before the beginning of the Soviet regime, two very important translations by Masing were published: Rabindranath Tagore’s Gitanjali and The Gardener, and a new translation of the Bible (Masing was one of three translators. In the Soviet era, Masing translated constantly from material that interested him and that was available to him (the poetry of Shanfara, Omar Khayyam, Matsuo Bashô, Louise Labé, Tagore et al.. As might be expected, from the standpoint of publication, the Stalinist period was Masing’s least productive period as a translator: in Estonia only one excerpt was published in a school textbook and without the name of the translator; a few new editions of Tagore’s prose poems were published in exile. From the 1960s on, as controls on society relaxed, Masing’s name as a translator returned little by little to the public eye. At that time, Masing was in greater favour as a translator than he was as a poet; this was the case for many other translators who were also poets. In the 1960s, many different poetry translations by Masing appeared along with commentary by the translator; reviews were also published. The mid–1970s was also an influential period, when the new editions of Tagore’s prose poetry collections The Gardener and Gitanjali appeared; the impact of these books persisted long

  16. Clasificación de reactivos químicos en los laboratorios de la Universidad Nacional Classification of chemical reagents in the laboratories of National University

    Directory of Open Access Journals (Sweden)

    José Carlos Mora Barrantes

    2012-11-01

    Full Text Available Durante el periodo 2008-2010 se realizaron inventarios de los reactivos químicos utilizados y almacenados en los laboratorios de los campus Omar Dengo y Benjamín Núñez de la Universidad Nacional. Se le solicitó a cada coordinador de laboratorio completar un formulario que incluía el nombre, la cantidad y el número CAS de los reactivos químicos almacenados y utilizados en cada laboratorio. Con estos datos, se clasificaron los reactivos de acuerdo con su categoría de peligro, utilizando el Código IMDG de la Organización de las Naciones Unidas (ONU. La clasificación de los reactivos químicos permitió el desarrollo de sus patrones de distribución en las diferentes unidades, institutos y centros de investigación de la Universidad Nacional. Además, se identificaron las clases de reactivos de mayor y menor uso en los laboratorios de la institución. El adecuado manejo de los reactivos químicos, con su correspondiente clasificación basada en la categoría de riesgo, es la base principal para la implementación de un ambiente seguro de trabajo en los laboratorios. La clasificación de los reactivos químicos permite minimizar los costos administrativos, económicos, legales, de seguridad y técnicos asociados con la atención de emergencias químicas; permitiendo además el desarrollo y aplicación de prácticas de trabajo preventivas por parte de funcionarios y estudiantes durante la manipulación de estas sustancias.During 2008-2010 inventories of chemical reagents used and stored in teaching and research laboratories of Omar Dengo and Benjamín Núñez campuses of National University were generated. E ach laboratory coordinator was asked to fill out a form that included name, quantity and CAS number of every chemical reagent stored and utilized in the laboratories. Chemical reagents were then classified according to the risk categories described by the United Nations IMDG Code. Such a classification process allowed the development

  17. A qualitative study exploring issues related to medication management in residential aged care facilities

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    Ahmad Nizaruddin M

    2017-11-01

    Full Text Available Mariani Ahmad Nizaruddin, Marhanis-Salihah Omar, Adliah Mhd-Ali, Mohd Makmor-Bakry Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia Background: Globally, the population of older people is on the rise. As families are burdened with the high cost of care for aging members, demand is increasing for medical care and nursing homes. Thus, medication management is crucial to ensure that residents in a care center benefit and assist the management of the care center in reducing the burden of health care. This study is aimed to qualitatively explore issues related to medication management in residential aged care facilities (RACFs.Participants and methods: A total of 11 stakeholders comprising health care providers, administrators, caretakers and residents were recruited from a list of registered government, nongovernmental organization and private RACFs in Malaysia from September 2016 to April 2017. An exploratory qualitative study adhering to Consolidated Criteria for Reporting Qualitative Studies was conducted. In-depth interview was conducted with consent of all participants, and the interviews were audio recorded for later verbatim transcription. Observational analysis was also conducted in a noninterfering manner.Results and discussion: Three themes, namely medication use process, personnel handling medications and culture, emerged in this study. Medication use process highlighted an unclaimed liability for residents’ medication by the RACFs, whereas personnel handling medications were found to lack sufficient training in medication management. Culture of the organization did affect the medication safety and quality improvement. The empowerment of the residents in their medication management was limited. There were unclear roles and responsibility of who manages the medication in the nongovernment-funded RACFs, although they were well structured in the private nursing homes.Conclusion: There are important issues

  18. THE INDEPENDENCE OF SOUTH AFRICAN JUDGES: A CONSTITUTIONAL AND LEGISLATIVE PERSPECTIVE

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    Lunga Siyo

    2015-11-01

    Full Text Available Judicial independence is fundamental to democracy. It is in that context that this paper considers whether the existing constitutional and legislative mechanisms provide sufficient judicial independence to South African judges. In so doing, the paper focuses on impartiality, judicial appointments and security of tenure. It also discusses the sensitive matter of complaints and disciplinary proceedings against judges and their removal from office. The issue of the remuneration of judges is also explored. In discussing the challenges facing judicial independence some incidents that have appeared to compromise such independence are highlighted. These include the controversial appointments of Advocate Mpshe as an acting judge in the North West Province in 2010 and Judge Heath as the Head of the Special Investigative Unit (SIU in 2011. The never-ending controversy surrounding the Cape Judge President John Hlophe and his alleged attempts to improperly influence two Constitutional Court judges in a case involving President Jacob Zuma is also highlighted. Another issue that has brought judicial independence into sharp focus is the June 2015 visit to South Africa of Sudan's President Omar al-Bashir, who was on a warrant of arrest from the International Criminal Court (ICC for genocide and war crimes in the Darfur region of Sudan. A decision by the North Gauteng High Court on his presence in South Africa and the attacks on the judiciary made by various government officials as a result are discussed. Several conclusions are drawn but in the main, it is generally concluded that the constitutional and legislative framework adopted by South Africa sufficiently insulates judges from improper influence. However, there have been several notable challenges that particularly relate to judicial appointments and how the JSC has handled certain matters. Irresponsible and uninformed political statements by politicians and unwarranted political attacks on the judiciary

  19. The International Criminal Court at the crossroads

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    Abdelwahab Biad

    2010-05-01

    Full Text Available Since the adoption of the Statute of Rome in July 1998, the ICC has been confronted by a number of problems. One such problem is the disagreement which persists among the members of the Assembly of Member States as to whether the crime of Aggression is one over which the Court has competence pursuant to Article 5 of the Statute. Another diffi culty is the opposition of the United States of America which, since the Bush Administration, has deployed a juridical arsenal with the aim of impeding any type of collaboration with the ICC; the tools in the arsenal include the American Service Members’ Protection Act and bilateral immunity agreements which prevent the transfer of American citizens to the Court by State members of the Rome Statute. The entry into force of the of the Statute on 1 July 2002 allowed the Court Prosecutor to initiate the fi rst investigations and processes for war crimes and crimes against humanity committed in the confl icts which have devastated certain African States (D.R.C., The Central African Republic and Uganda. The arrest warrant against the Sudanese President Omar Al Bashir for atrocities committed in Darfur demonstrates the limitations of action on the Court which cannot carry out its mandate without the cooperation of the States. Above all, the Court must confront the criticism of “double standards” and that it is an instrument of “justice for the poor”, while the “powerful” escape. The answers to these problems can be contributed to, in part, through the revision process foreseen by the Statute nine years after its entry into force.

  20. Development of TUA-WELLNESS screening tool for screening risk of mild cognitive impairment among community-dwelling older adults

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    Vanoh D

    2016-05-01

    Full Text Available Divya Vanoh,1 Suzana Shahar,1 Razali Rosdinom,2 Normah Che Din,3 Hanis Mastura Yahya,4 Azahadi Omar5 1Dietetic Programme, Centre of Healthcare Sciences, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia; 2Department of Psychiatry, University Kebangsaan Medical Centre, Kuala Lumpur, Malaysia; 3Health Psychology Programme, 4Nutrition Programme, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia; 5Institute of Public Health, Ministry of Health, Kuala Lumpur, Malaysia Background and aim: Focus on screening for cognitive impairment has to be given particular importance because of the rising older adult population. Thus, this study aimed to develop and assess a brief screening tool consisting of ten items that can be self-administered by community dwelling older adults (TUA-WELLNESS. Methodology: A total of 1,993 noninstitutionalized respondents aged 60 years and above were selected for this study. The dependent variable was mild cognitive impairment (MCI assessed using neuropsychological test batteries. The items for the screening tool comprised a wide range of factors that were chosen mainly from the analysis of ordinal logistic regression (OLR and based on past literature. A suitable cut-off point was developed using receiver operating characteristic analysis. Results: A total of ten items were included in the screening tool. From the ten items, eight were found to be significant by ordinal logistic regression and the remaining two items were part of the tool because they showed strong association with cognitive impairment in previous studies. The area under curve (AUC, sensitivity, and specificity for cut-off 11 were 0.84%, 83.3%, and 73.4%, respectively. Conclusion: TUA-WELLNESS screening tool has been used to screen for major risk factors of MCI among Malaysian older adults. This tool is only suitable for basic MCI risk screening purpose and should not be used for diagnostic

  1. Concurrent sexual partnerships among married Zimbabweans – implications for HIV prevention

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    Mugweni E

    2015-09-01

    Full Text Available Esther Mugweni,1 Stephen Pearson,2 Mayeh Omar2 1UCL Department of Infection and Population Health, University College London, London, 2The Nuffield Centre for International Health and Development, University of Leeds, Leeds, UK Background: Concurrent sexual partnerships play a key role in sustaining the HIV epidemic in Zimbabwe. Married couples are at an increased risk of contracting HIV from sexual networks produced by concurrent sexual partnerships. Addressing these partnerships is an international HIV prevention priority. Methods: Our qualitative study presents the socioeconomic factors that contribute to the occurrence of concurrent sexual partnerships among married people in Zimbabwe. We conducted 36 in-depth interviews and four focus group discussions with married men and women in Zimbabwe in 2008 to understand the organizations of concurrent sexual partnerships. Data were analyzed using framework analysis. Results: Our study indicates that relationship dissatisfaction played a key role in the engagement of concurrent sexual partnerships. Depending on the source of the dissatisfaction, there were four possible types of concurrent sexual relationships that were formed: sex worker, casual partner, regular girlfriend or informal polygyny which was referred to as “small house”. These relationships had different levels of intimacy, which had a bearing on practicing safer sex. Participants described three characteristics of hegemonic masculinity that contributed to the sources of dissatisfaction leading to concurrent sexual activity. Similarly, various aspects of emphasized femininity were described as creating opportunities for the occurrence of concurrent sexual relationships. Economic status was also listed as a factor that contributed to the occurrence of concurrent sexual partnerships. Conclusion: Marital dissatisfaction was indicated as a contributing factor to the occurrence of concurrent sexual relationships. There were several

  2. Differential clinical pharmacology of rolapitant in delayed chemotherapy-induced nausea and vomiting (CINV

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    Rashad N

    2017-03-01

    Full Text Available Noha Rashad,1 Omar Abdel-Rahman2 1Medical Oncology Department, Maadi Armed Forces Hospital, 2Clinical Oncology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt Abstract: Rolapitant is a highly selective neurokinin-1 receptor antagonist, orally administered for a single dose of 180 mg before chemotherapy with granisetron D1, dexamethasone 8 mg BID on day 2–4. It has a unique pharmacological characteristic of a long plasma half-life (between 163 and 183 hours; this long half-life makes a single use sufficient to cover the delayed emesis risk period. No major drug–drug interactions between rolapitant and dexamethasone or other cytochrome P450 inducers or inhibitors were observed. The clinical efficacy of rolapitant was studied in two phase III trials in highly emetogenic chemotherapy and in one clinical trial in moderately emetogenic chemotherapy. The primary endpoint was the proportion of patients achieving a complete response (defined as no emesis or use of rescue medication in the delayed phase (>24–120 hours after chemotherapy. In comparison to granisetron (10 µg/kg intravenously and dexamethasone (20 mg orally on day 1, and dexamethasone (8 mg orally twice daily on days 2–4 and placebo, rolapitant showed superior efficacy in the control of delayed and overall emesis. This review aims at revising the pharmacological characteristics of rolapitant, offering an updated review of the available clinical efficacy and safety data of rolapitant in different clinical settings, highlighting the place of rolapitant in the management of chemotherapy-induced nausea and vomiting (CINV among currently available guidelines, and exploring the future directions of CINV management. Keywords: nausea, vomiting, chemotherapy, rolapitant, CINV

  3. Adalimumab impact on fatigue measured by FACIT-F: a study of rheumatoid arthritis patients in Saudi Arabia

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    Janoudi N

    2017-10-01

    Full Text Available Nahed Janoudi,1 Narges Omran,2 Waleed Hussain,3 Hanan Al-osaimi,4 Matouqa Baamer,5 Muhammad Irfanullah Siddiqui,6 Omar Fathaldin,7 Hani Almoallim1,4,8 1Department of Medicine, Dr. Soliman Fakeeh Hospital, Jeddah, 2Department of Medicine, Alnoor General Hospital, 3Department of Medicine, Heraa General Hospital, 4Alzaidi Chair of Research in Rheumatic Diseases, Umm Al-Qura University, Makkah, 5Department of Medicine, King Abdulaziz Hospital & Oncology Center, Jeddah, 6Department of Community Medicine and Public Health, Faculty of Medicine, Umm Al-Qura University, Makkah, 7Department of Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, 8Department of Medicine, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia Objective: The objective of the study was to assess the effectiveness of adalimumab as a treatment for fatigue in patients with rheumatoid arthritis (RA. Methods: Fatigue was monitored in patients with RA who were already on an adalimumab treatment regimen. Fatigue, general well-being, comorbidities, and disease activity were measured at baseline and ~8, 16, and 24 weeks, thereafter. Results: Significant reductions in fatigue scores and disease activity were observed from baseline to 6 months after. A predictive regression model of fatigue severity was proposed and was found to be significant, with RA disease activity as the most significant predictor of fatigue severity. Conclusion: This quasi-experimental study is a good starting point for research on the efficacy of adalimumab in treating fatigue in RA patients. The results here suggest that a randomized controlled trial assessing adalimumab as a treatment option for RA patients suffering from fatigue is warranted. Keywords: rheumatoid arthritis, fatigue, adalimumab, disease activity, Saudi Arabia, FACIT-F 

  4. Sodium hypochlorite accident resulting in life-threatening airway obstruction during root canal treatment: a case report

    Directory of Open Access Journals (Sweden)

    Al-Sebaei MO

    2015-03-01

    Full Text Available Maisa O Al-Sebaei,1 Omar A Halabi,2 Ibrahim E El-Hakim3 1Department of Oral and Maxillofacial Surgery, King Abdulaziz University – Faculty of Dentistry, Jeddah, Kingdom of Saudi Arabia; 2Saudi Board of Oral and Maxillofacial Surgery, Al-Noor Specialist Hospital, Makkah, Kingdom of Saudi Arabia; 3Department of Oral and Maxillofacial Surgery, Riyadh Colleges of Dentistry and Pharmacy, Riyadh, Kingdom of Saudi Arabia Aim: This case report describes a serious and life-threatening complication of the use of sodium hypochlorite as an irrigation solution in root canal therapy. Summary: This case report describes a hypochlorite accident that occurred in a healthy 42-year-old female who was undergoing routine root canal therapy for the lower right central incisor (tooth #41. After approximately 1 hour of irrigation with 3% sodium hypochlorite (for a total of 12 cc, the patient complained of severe pain and burning in the lip. The swelling progressed over the next 8 hours to involve the sublingual and submental fascial spaces with elevation of the tongue and resultant upper airway obstruction. The patient was intubated and remained on mechanical ventilation for 3 days. She recovered without any skin necrosis or nerve deficits. Key learning points: This case report highlights the importance of carefully performing root canal irrigation with sodium hypochlorite to avoid complications. Careful injection without pressure, the use of proper rubber dam isolation, and the use of the endodontic needle are necessary to avoid this type of complication. Although it is a safe root canal irrigation solution, its use may lead to life-threatening complications. Early recognition and management of the untoward effects of sodium hypochlorite are vital for the patient's safety. Keywords: complications of root canal, facial edema, root canal irrigation, root canal therapy, sodium hypochlorite, upper airway obstruction

  5. Refinement of clinical X-ray computed tomography (CT) scans containing metal implants.

    Science.gov (United States)

    Treece, Graham

    2017-03-01

    X-ray computed tomography (CT) data contains artefacts from many sources, with sufficient prominence to affect diagnostic utility when metal is present in the scans. These artefacts can be reduced, usually by the removal and in-filling of any sinogram data which has been affected by metal, and several such techniques have been proposed. Most of them are prone to introducing new artefacts into the CT data or may take a long time to correct the data. It is the purpose of this paper to introduce a new technique which is fast, yet can effectively remove most artefacts without introducing significant new ones. The new metal artefact reduction technique (RMAR) consists of an iterative refinement of the CT data by alternately forward- and back-projecting the part of the reconstruction near to metal. The forward-projection is corrected by making use of a prior derived from the reconstructed data which is independently estimated for each projection angle, and smoothed using a newly developed Bitonic filter. The new technique is compared with previously published (LI, NMAR, MDT) and commercial (O-MAR, IMAR) alternatives, quantitatively on phantom data, and qualitatively on a selection of clinical scans, mostly of the hip. The phantom data is from two recently published studies, enabling direct comparison with previous results. The results show an increased reduction of artefacts on the four phantom data sets tested. On two of the phantom data sets, RMAR is significantly better (pCT data, RMAR can correct each image in 3-8s, which is more than one hundred times faster than MDT. The new technique is demonstrated to have performance at least as good as MDT, with both out-performing other approaches. However, it is much faster then the latter technique, and shows better preservation of data very close to metal. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. The influence of humor styles in coping strategies in Entre Ríos

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    Pablo Roberto Lillo

    2015-09-01

    Full Text Available Over the last years there has been a growing interest in the study of the resources that people use from face to a problem. The interest in the study of the characteristics related to the humor has gone in increase, especially for the influence of the development of a new concept in psychology that derives in the call positive psychology (Seligman and Csikszentmihalyi, 2000; Zinder and McCullog 2000, in Martin, Puhlik-Doris, Larsen, Gray, Weir, 2003 which is centered in adaptive strengths such as optimism, faith, courage, as well as humor (Martin 2003, quoted in Martin et al., 2003. Sense of humor has been considered as an unidimensional construct (Omar, 1995 and the consequencies has been some errors in the assesment, as a result of a problem of validity. The present study seeks to introduce certain aspects that have not been considered in the past, so much the potential beneficial effects, as the deleterious forms of the sense of humor as for the psychological well-being. Four dimensions of the sense of humor were assesed (Martin, Puhlik-Doris, Larsen, Gray, Weir, 2003, version Lillo, 2006 relating to the uses or functions in everyday life and the ways of people cope (Fridenberg and Lewis, 1991, version Richaud de Minzi. 2003. They were also significant relationships among styles of humor and ways of coping that could explain the importance of the construct sense of humor, as an important resource to be used. Although it is necessary to highlight that it is not sought to embrace all the components of the sense of humor, but rather it is focused in the interpersonal functions and intrapsíquicas that adolescents use in daily life. These functions are considered most relevant to the well-being. Measuring these aspects of the humor, it is expected that they can explain a greater proportion of the variance as for the ways of people cope. 

  7. Stress, anxiety, and depression among parents of children with autism spectrum disorder in Oman: a case–control study

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    Al-Farsi OA

    2016-08-01

    Full Text Available Omar A Al-Farsi,1 Yahya M Al-Farsi,1,2 Marwan M Al-Sharbati,3 Samir H Al-Adawi31Department of Family Medicine and Public Health, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Sultanate of Oman; 2Department of Epidemiology, School of Public Health, Boston, MA, USA; 3Department of Behavioural Medicine, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Sultanate of Oman Abstract: Previous studies carried out in Euro-American populations have unequivocally indicated that psychological disorders of the CASD (caregivers of children with autism spectrum disorder are marked with high levels of stress, anxiety, and depression. This finding has been attributed to the reaction of having to care for a child with neurodevelopmental disorders. While there have been reports on autism spectrum disorder in Arab/Islamic countries such as Oman, there is no study from this region, to our knowledge, reporting the performance of indices of stress, anxiety, and depression among CASD. This study aimed to examine whether there is variation in the performance of indices of stress, depression, and anxiety explored via Depression, Anxiety and Stress Scale 21 among CASD, caregivers of children with intellectual disabilities, and caregivers of typically developing children. All indices of stress, depression, and anxiety were higher in CASD compared to other caregivers in the control group. This study corroborates with other studies carried out in other populations that caring for children impacts the mental health status of caregivers. Therefore, there are strong grounds to contemplate the mechanism to help such a vulnerable group of family caregivers. Keywords: stress, anxiety, depression, caregivers, autism, Oman

  8. The fate of river organic carbon in coastal areas: A study in the Rhône River delta using multiple isotopic (δ13C, Δ14C) and organic tracers

    Science.gov (United States)

    Cathalot, C.; Rabouille, C.; Tisnérat-Laborde, N.; Toussaint, F.; Kerhervé, P.; Buscail, R.; Loftis, K.; Sun, M.-Y.; Tronczynski, J.; Azoury, S.; Lansard, B.; Treignier, C.; Pastor, L.; Tesi, T.

    2013-10-01

    A significant fraction of the global carbon flux to the ocean occurs in River-dominated Ocean Margins (RiOMar) although large uncertainties remain in the cycle of organic matter (OM) in these systems. In particular, the OM sources and residence time have not been well clarified. Surface (0-1 cm) and sub-surface (3-4 cm) sediments and water column particles (bottom and intermediate depth) from the Rhône River delta system were collected in June 2005 and in April 2007 for a multi-proxy study. Lignin phenols, black carbon (BC), proto-kerogen/BC mixture, polycyclic aromatic hydrocarbons (PAHs), carbon stable isotope (δ13COC), and radiocarbon measurements (Δ14COC) were carried out to characterize the source of sedimentary organic material and to address degradation and transport processes. The bulk OM in the prodelta sediment appears to have a predominantly modern terrigenous origin with a significant contribution of modern vascular C3 plant detritus (Δ14COC = 27.9‰, δ13COC = -27.4‰). In contrast, the adjacent continental shelf, below the river plume, seems to be dominated by aged OM (Δ14COC = -400‰, δ13COC = -24.2‰), and shows no evidence of dilution and/or replacement by freshly produced marine carbon. Our data suggest an important contribution of black carbon (50% of OC) in the continental shelf sediments. Selective degradation processes occur along the main dispersal sediment system, promoting the loss of a modern terrestrial OM but also proto-kerogen-like OM. In addition, we hypothesize that during the transport across the shelf, a long term resuspension/deposition loop induces efficient long term degradation processes able to rework such refractory-like material until the OC is protected by the mineral matrix of particles.

  9. An Experimental Study on the Convective Heat Transfer in Narrow Rectangular Channels for Downward Flow to Predict Onset of Nucleate Boiling

    International Nuclear Information System (INIS)

    Song, Junghyun; Jeong, Yong Hoon; Lee, Juhyung; Chang, Soon Heung

    2014-01-01

    Research reactor is the nuclear reactor serves neutron source for many research fields such as neutron scattering, non-destructive testing, radioisotope treatment and so on. Due to that characteristic of research reactor, as many people work around the research reactor, research reactor should be designed to have much more conservative margin for normal operation. Boiling heat transfer is the one of the most efficient type in heat transfer modes, however, research reactor needs to avoid onset of nucleate boiling (ONB) in normal operation as IAEA recommend for research reactors to have enough ONB margin to maintain the normal operation state in 'IAEA-TECDOC-233' (1980) for the same reason explained above. Jordan Research and Training Reactor (JRTR) operates under downward flow in narrow rectangular channel in fuel assembly. There isn't sufficient heat transfer data under downward flow condition and only few ONB prediction correlation as well. In the present work, not only a new ONB prediction model would be developed, but also comparison between heat transfer data with several heat transfer correlations could be shown. In addition, as Sudo and Omar S. proposed differently about the Nusselt number behaviors in upward and downward convective heat transfer, the study of convective heat transfer should be conducted continuously to determine it exactly. In this paper, single-phase heat transfer data is analyzed by several heat transfer correlations before developing ONB prediction correlation. In this study, an experiment on the single-phase heat transfer was conducted. As shown in Fig. 5, comparison between experimental data and existing correlations shows quite huge difference as about 40%. Additional experiments on single-phase heat transfer at low heat flux are necessary to clarify the tendency of Nusselt number among heat flux and to develop new correlation for single-phase heat transfer

  10. Alterations in oral microbial flora induced by waterpipe tobacco smoking

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    Shakhatreh MAK

    2018-02-01

    Full Text Available Muhamad Ali K Shakhatreh,1 Omar F Khabour,1 Karem H Alzoubi,2 Majed M Masadeh,3 Emad I Hussein,4 George N Bshara1 1Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, Irbid, Jordan; 2Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan; 3Department of Pharmaceutical Technology, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan; 4Department of Biological Sciences, Yarmouk University, Irbid, Jordan Background: Waterpipe smoking is a global health problem and a serious public concern. Little is known about the effects of waterpipe smoking on oral health. In the current study, we examined the alterations of oral microbial flora by waterpipe smoking. Methods: One hundred adult healthy subjects (59 waterpipe smokers and 41 non-smokers were recruited into the study. Swabs were taken from the oral cavity and subgingival regions. Standard culturing techniques were used to identify types, frequency, and mean number of microorganisms in cultures obtained from the subjects. Results: It was notable that waterpipe smokers were significantly associated with a history of oral infections. In subgingiva, Acinetobacter and Moraxella species were present only in waterpipe smokers. In addition, the frequency of Candida albicans was higher in the subgingiva of waterpipe smokers (p = 0.023 while the frequency of Fusobacterium nucleatum was significantly lower in the subgingiva of waterpipe smokers (p = 0.036. However, no change was observed in other tested bacteria, such as Campylobacter species; Viridans group streptococci, Enterobacteriaceae, and Staphylococcus aureus. In oral cavity and when colony-forming units were considered, the only bacterial species that showed significant difference were the black-pigmented bacteria (p < 0.001. Conclusion: This study provides evidence indicating that some of the oral microflora is significantly altered by

  11. Triple therapy in COPD: new evidence with the extrafine fixed combination of beclomethasone dipropionate, formoterol fumarate, and glycopyrronium bromide

    Directory of Open Access Journals (Sweden)

    Singh D

    2017-10-01

    Full Text Available Dave Singh,1 Massimo Corradi,2 Monica Spinola,3 Alberto Papi,4 Omar S Usmani,5 Mario Scuri,3 Stefano Petruzzelli,3 Jørgen Vestbo1 1Division of Infection, Immunity and Respiratory Medicine, University of Manchester, Manchester, UK; 2Department of Medicine and Surgery, University of Parma, Parma, Italy; 3Chiesi Farmaceutici SpA, Parma, Italy; 4Department of Medical Sciences, Research Centre on Asthma and COPD, University of Ferrara, Ferrara, Italy; 5National Heart and Lung Institute, Imperial College London, London, UK Abstract: The goals of COPD therapy are to prevent and control symptoms, reduce the frequency and severity of exacerbations, and improve exercise tolerance. The triple combination therapy of inhaled corticosteroids (ICSs, long-acting beta2 agonists (LABAs, and long-acting muscarinic antagonists (LAMAs has become an option for maintenance treatment of COPD and as a “step-up” therapy from single or double combination treatments. There is evidence that triple combination ICS/LABA/LAMA with different inhalers improves lung function, symptoms, and health status and reduces exacerbations. A new triple fixed-dose combination of extrafine beclomethasone dipropionate (100 µg/puff/formoterol fumarate (6 µg/puff/glycopyrronium bromide (12.5 µg/puff has been developed as a hydrofluoroalkane pressurized metered dose inhaler. Two large pivotal studies showed that this extrafine fixed ICS/LABA/LAMA triple combination is superior to fixed ICS/LABA combined therapy and also superior to the LAMA tiotropium in terms of lung function and exacerbation prevention in COPD patients at risk of exacerbation. This review considers the new information provided by these clinical trials of extrafine triple therapy and the implications for the clinical management of COPD patients. Keywords: COPD, inhaled triple therapy, beclomethasone dipropionate, formoterol fumarate and glycopyrronium bromide

  12. The Support System in Distance Education:Factors Affecting Achievements Among Women Learners

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    Rozhan M IDRUS

    2005-10-01

    Full Text Available The Support System in Distance Education:Factors Affecting Achievements Among Women Learners Hanafi ATAN Zuraidah A. RAHMAN Omar MAJID Noraida A. GHANIRozhan M IDRUS School of Distance EducationUniversiti Sains Malaysia11800 Penang, MALAYSIA ABSTRACT Distance education has the potential to contribute to the enhancement of women’s development by overcoming not only temporal and spatial barriers but familial commitments as well. It brings education to their home and allows women to learn at their individual pace, seek skills for individual development and at the same time, enables them to fulfill family responsibilities. An important element of distance education is the provision of the learner support system that provides students the access to learning resources and means of communication that would facilitate the array of educational activities and exposure to various other guidance and advisories. This paper reports on the study undertaken to elucidate the dimensions of the support system provided by the School of Distance Education (SDE, Universiti Sains Malaysia (USM to its women learners that would have significant impact on their achievements. The factorial analysis conducted revealed that the role of the faculty is the main contributing factor affecting these achievements, followed by the provision of the intensive course, the electronic portal, video conferencing and to a much lesser extent, the existence of the regional centres. The implications of this study are discussed with the view of improving the support system provided by the institution and the need to put into action the necessary strategies to further improve the achievement of the women learners.

  13. Hereditary hemorrhagic telangiectasia and pregnancy: potential adverse events and pregnancy outcomes

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    Bari O

    2017-05-01

    Full Text Available Omar Bari,1 Philip R Cohen2 1School of Medicine, University of California San Diego, La Jolla, CA, USA; 2Department of Dermatology, University of California San Diego, La Jolla, CA, USA Abstract: Hereditary hemorrhagic telangiectasia (HHT is an autosomal dominant condition with a prevalence of ~1 in 5,000 individuals. The pathophysiology of this condition centers on the lack of capillary beds between arterioles and venules, leading to direct contact between these vessels. This results in telangiectases on characteristic locations such as the face, fingers, mouth, and nasal mucosa. Visceral arteriovenous malformations (AVMs are also observed in many patients, and these are most commonly seen in the brain, gastrointestinal tract, and lungs. Liver AVMs are present in many patients with HHT, though these individuals are usually asymptomatic; however, liver AVMs may lead to serious complications, such as high output cardiac failure. Diagnosis of HHT hinges upon fulfilling three out of four criteria: family history of the condition, mucocutaneous telangiectases, spontaneous and recurrent episodes of epistaxis, and visceral AVMs. Management is guided by international consensus guidelines and targets patients’ specific AVMs. Prognosis is good, though severe complications including hemorrhage and paradoxical emboli are possible. Novel therapeutics are being explored in clinical trials; bevacizumab and pazopanib inhibit angiogenesis, while thalidomide bolsters blood vessel maturation. Pregnancy in patients with HHT is considered high risk. While the majority of pregnancies proceed normally, severe complications have been reported in some women with HHT; these include heart failure, intracranial hemorrhage, pulmonary hemorrhage, and stroke. Such complications occur most often in the second and third trimesters when maternal changes such as peripheral vasodilation and increased cardiac output are at their maximum. Awareness of the diagnosis of HHT has

  14. Alpha antagonists and intraoperative floppy iris syndrome: A spectrum

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    Sharif A Issa

    2008-07-01

    Full Text Available Sharif A Issa, Omar H Hadid, Oliver Baylis, Margaret DayanDepartment of Ophthalmology, Royal Victoria Infirmary, Newcastle upon Tyne, UKBackground: To determine occurrence of features of intraoperative floppy iris syndrome (IFIS during cataract surgery in patients taking systemic alpha-antagonists (AA.Methods: We prospectively studied patients on AA and who underwent phacoemulsification. The following were recorded: pupil diameter preoperatively, iris flaccidity, iris prolapse and peroperative miosis.Results: We studied 40 eyes of 31 subjects. Mean age was 78 years. Overall, 14 eyes (13 patients showed signs of IFIS: 9/13 (69% eyes of patients on tamsulosin, 1/18 (6% eyes in the doxazosin group, 2/2 prazosin patients, 1/4 eyes in the indoramin group, and 1/2 eyes in two patients on a combination of doxazosin and tamsulosin. Most cases (92% had only one or two signs of IFIS. Bilateral cataract surgery was undertaken in 9 patients but only one patient (on tamsulosin had features of IFIS in both eyes, while 4 patients (2 on tamsulosin and 2 on other AA showed signs of IFIS in one eye only, and 4 patients did not show IFIS in either eye.Conclusion: Most AA were associated with IFIS, but it tends to present as a spectrum of signs rather than full triad originally described. Tamsulosin was most likely to be associated with IFIS; however, its intake does not necessarily mean that IFIS will occur. For patients on AA, the behavior of the iris intraoperatively in one eye is a poor predictor of the other eye. Surgeons should anticipate the occurrence of IFIS in any patient on AA.Keywords: alpha blocker, alpha antagonist, cataract surgery, intraoperative floppy iris syndrome, tamsulosin.

  15. Breast cancer characteristics in very young Egyptian women ≤35 years

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    Farouk O

    2016-04-01

    Full Text Available Omar Farouk,1 Mohamed A Ebrahim,2 Ahmad Senbel,1 Ziad Emarah,2 Waleed Abozeed,3 Mohamed O Seisa,4 Summer Mackisack,4 Salah Abdel Jalil,4 Safaa Abdelhady4 1Surgical Oncology Unit, 2Medical Oncology Unit, Oncology Center, Faculty of Medicine, 3Clinical Oncology and Nuclear Medicine Department, 4Faculty of Medicine, Mansoura University, Mansoura, Egypt Background: Breast cancer in very young patients represents a unique issue that needs more attention as the number of cases is increasing and it has special characteristics at presentation, diagnosis, and biologic behaviors which reflect on both treatment strategies and survival. The aim of the current study was to analyze and report the clinico-pathological characteristics and treatment procedures used for breast cancer in very young patients over the last decade in a single Egyptian cancer center. Patients and methods: A retrospective study was conducted in the Oncology Center – Mansoura University, where the data of all breast cancer patients, between September 2006 and August 2015, were reviewed. Among 4,628 patients who were diagnosed with breast cancer during this period, only 300 patients aged ≤35 years had complete registry data. Clinico-pathological characteristics, therapeutic procedures, and survival outcome were reported. Results: Three hundred and seventy-nine patients (8.19% were aged ≤35 years at the time of presentation. The age ranged between 21 and 35 years, and the mean age was 31 years (±3 standard deviation. Positive family history of breast cancer was found in 12.3%, and metastatic presentation was seen in 4.7%. The rate of axillary lymph nodes involvement was 75.7%. The estrogen receptor-negative disease was found in 51%, and among 217 patients who did HER2 test, 82 patients (37.8% were HER2 positive, while triple-negative subtype was found in 57 patients (26.4%. Ki 67 percentage ranged between 3% and 66% (median was 35%. The median disease-free survival was 61 months

  16. Changes in ventilation–perfusion during and after an COPD exacerbation: an assessment using fluid dynamic modeling

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    Hajian B

    2018-03-01

    Full Text Available Bita Hajian,1 Jan De Backer,2 Wim Vos,2 Wouter H van Geffen,3 Paul De Winter,1 Omar Usmani,4 Tony Cahn,5 Huib AM Kerstjens,3 Massimo Pistolesi,6 Wilfried De Backer1 1Department of Respiratory Medicine, University Hospital Antwerp, Edegem, Belgium; 2FLUIDDA nv, Kontich, Belgium; 3Department of Respiratory Medicine, University Medical Center Groningen, Groningen, the Netherlands; 4Department of Pulmonology, Brompton Hospital, London, UK; 5GSK, London, UK; 6Department of Pulmonary Diseases, University of Firenze, Florence, Italy Introduction: Severe exacerbations associated with chronic obstructive pulmonary disease (COPD that require hospitalization significantly contribute to morbidity and mortality. Definitions for exacerbations are very broad, and it is unclear whether there is one predominant underlying mechanism that leads to them. Functional respiratory imaging (FRI with modeling provides detailed information about airway resistance, hyperinflation, and ventilation–perfusion (V/Q mismatch during and following an acute exacerbation. Materials and methods: Forty-two patients with COPD participating in a multicenter study were assessed by FRI, pulmonary function tests, and self-reported outcome measures during an acute exacerbation and following resolution. Arterial blood gasses and lung function parameters were measured. Results: A significant correlation was found between alveolar–arterial gradient and image-based V/Q (iV/Q, suggesting that iV/Q represents V/Q mismatch during an exacerbation (p<0.05. Conclusion: Recovery of an exacerbation is due to decreased (mainly distal airway resistance (p<0.05. Improvement in patient-reported outcomes were also associated with decreased distal airway resistance (p<0.05, but not with forced expiratory volume. FRI is, therefore, a sensitive tool to describe changes in airway caliber, ventilation, and perfusion during and after exacerbation. On the basis of the fact that FRI increased distal airway

  17. Topical piroxicam in vitro release and in vivo anti-inflammatory and analgesic effects from palm oil esters-based nanocream

    Directory of Open Access Journals (Sweden)

    Muthanna F Abdulkarim

    2010-11-01

    Full Text Available Muthanna F Abdulkarim1*, Ghassan Z Abdullah1*, Mallikarjun Chitneni2, Ibrahim M Salman1, Omar Z Ameer1, Mun F Yam1,3, Elrashid S Mahdi1, Munavvar A Sattar1, Mahiran Basri4, Azmin M Noor11School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia; 2School of Pharmacy and Health Sciences, International Medical University, Kuala Lumpur, Malaysia; 3Faculty of Medicine and Health Sciences, 4Faculty of Science, Universiti Putra Malaysia, Selangor, Malaysia; *The First and Second Authors have Contributed Equally to this WorkIntroduction: During recent years, there has been growing interest in use of topical vehicle systems to assist in drug permeation through the skin. Drugs of interest are usually those that are problematic when given orally, such as piroxicam, a highly effective anti-inflammatory, antipyretic, and analgesic, but with the adverse effect of causing gastrointestinal ulcers. The present study investigated the in vitro and in vivo pharmacodynamic activity of a newly synthesized palm oil esters (POEs-based nanocream containing piroxicam for topical delivery.Methods: A ratio of 25:37:38 of POEs: external phase: surfactants (Tween 80:Span 20, in a ratio 80:20, respectively was selected as the basic composition for the production of a nanocream with ideal properties. Various nanocreams were prepared using phosphate-buffered saline as the external phase at three different pH values. The abilities of these formulae to deliver piroxicam were assessed in vitro using a Franz diffusion cell fitted with a cellulose acetate membrane and full thickness rat skin. These formulae were also evaluated in vivo by comparing their anti-inflammatory and analgesic activities with those of the currently marketed gel.Results: After eight hours, nearly 100% of drug was transferred through the artificial membrane from the prepared formula F3 (phosphate-buffered saline at pH 7.4 as the external phase and the marketed gel. The steady-state flux

  18. Targeting brain cells with glutathione-modulated nanoliposomes: in vitro and in vivo study

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    Salem HF

    2015-07-01

    Full Text Available Heba F Salem,1 Sayed M Ahmed,2 Ashraf E Hassaballah,3 Mahmoud M Omar1,4 1Department of Pharmaceutics and Industrial Pharmacy, Beni-suef University, 2Department of Industrial Pharmacy, Assiut University, 3Department of Clinical Pathology, Faculty of Medicine, Assiut University, Assuit, 4Department of Pharmaceutics and Industrial Pharmacy, Deraya University, Egypt Background: The blood–brain barrier prevents many drug moieties from reaching the central nervous system. Therefore, glutathione-modulated nanoliposomes have been engineered to enhance the targeting of flucytosine to the brain. Methods: Glutathione-modulated nanoliposomes were prepared by thin-film hydration technique and evaluated in the primary brain cells of rats. Lecithin, cholesterol, and span 65 were mixed at 1:1:1 molar ratio. The molar percentage of PEGylated glutathione varied from 0 mol% to 0.75 mol%. The cellular binding and the uptake of the targeted liposomes were both monitored by epifluorescent microscope and flow cytometry techniques. A biodistribution and a pharmacokinetic study of flucytosine and flucytosine-loaded glutathione–modulated liposomes was carried out to evaluate the in vivo brain-targeting efficiency. Results: The size of glutathione-modulated nanoliposomes was <100 nm and the zeta potential was more than -65 mV. The cumulative release reached 70% for certain formulations. The cellular uptake increased as molar percent of glutathione increased to reach the maximum at 0.75 mol%. The uptake of the targeted liposomes by brain cells of the rats was three times greater than that of the nontargeted liposomes. An in vivo study showed that the relative efficiency was 2.632±0.089 and the concentration efficiency was 1.590±0.049, and also, the drug-targeting index was 3.670±0.824. Conclusion: Overall, these results revealed that glutathione-PEGylated nanoliposomes enhance the effective delivery of flucytosine to brain and could become a promising new

  19. Liposomal flucytosine capped with gold nanoparticle formulations for improved ocular delivery

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    Salem HF

    2016-01-01

    Full Text Available Heba F Salem,1 Sayed M Ahmed,2 Mahmoud M Omar3 1Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt; 2Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt; 3Department of Industrial Pharmacy, Faculty of Pharmacy, Deraya University, El-Minia, Egypt Abstract: Nanoliposomes have an organized architecture that provides versatile functions. In this study, liposomes were used as an ocular carrier for nanogold capped with flucytosine antifungal drug. Gold nanoparticles were used as a contrasting agent that provides tracking of the drug to the posterior segment of the eye for treating fungal intraocular endophthalmitis. The nanoliposomes were prepared with varying molar ratios of lecithin, cholesterol, Span 60, a positive charge inducer (stearylamine, and a negative charge inducer (dicetyl phosphate. Formulation F6 (phosphatidylcholine, cholesterol, Span 60, and stearylamine at a molar ratio of 1:1:1:0.15 demonstrated the highest extent of drug released, which reached 7.043 mg/h. It had a zeta potential value of 42.5±2.12 mV and an average particle size approaching 135.1±12.0 nm. The ocular penetration of the selected nanoliposomes was evaluated in vivo using a computed tomography imaging technique. It was found that F6 had both the highest intraocular penetration depth (10.22±0.11 mm as measured by the computed tomography and the highest antifungal efficacy when evaluated in vivo using 32 infected rabbits’ eyes. The results showed a strong correlation between the average intraocular penetration of the nanoparticles capped with flucytosine and the percentage of the eyes healed. After 4 weeks, all the infected eyes (n=8 were significantly healed (P<0.01 when treated with liposomal formulation F6. Overall, the nanoliposomes encapsulating flucytosine have been proven efficient in treating the infected rabbits’ eyes, which proves the efficiency of the

  20. Cicatrização da membrana timpânica na timpanocentese com laser de argônio comparado à técnica com microlanceta: estudo experimental em ratos Tympanic membrane healing in myringotomies performed with argon laser or microknife: an experimental study in rats

    Directory of Open Access Journals (Sweden)

    Lucio Almeida Castagno

    2006-12-01

    Full Text Available Otite média secretora (OMS e otite média aguda recorrente (OMAR podem necessitar tratamento cirúrgico para adequada ventilação da orelha média. A abertura clássica do tímpano (timpanocentese requer incisão por microlanceta sob controle de microscópio cirúrgico e mantém-se patente por alguns dias. Estudos recentes sugerem que a timpanocentese feita por diferentes lasers pode permanecer permeável por maior tempo, o que possibilitaria a normalização da otite média. MATERIAL E MÉTODOS: Neste estudo experimental 34 ratos linhagem Wistar, albinos, machos adultos pesando cerca de 300g, foram anestesiados com cetamina 27 mg/kg e xilazina 2,7 mg/kg. A seguir, foram submetidos à timpanocentese incisional com microlanceta no ouvido direito (ML-OD, e à timpanocentese mediada por laser de argônio no ouvido esquerdo (LA-OE. RESULTADOS: Não houve diferença significativa no tempo de cicatrização das timpanocenteses feitas com laser de argônio ou microlanceta. Todas as timpanocenteses cicatrizaram em 10 dias. CONCLUSÃO: A timpanocentese com laser de argônio apresentou patência e cicatrização semelhantes à técnica clássica com microlanceta realizada em ratos Wistar sem enfermidades de orelha média.Secretory otitis media (SOM and recurrent acute otitis media (RAOM may require surgical treatment to proper ventilate the middle ear. Incisional myringotomy is usually done under microscopy with a micro-knife , but it remains patent for just a few days. Recent research indicates that laser assisted myringotomies remain open much longer, allowing middle ear ventilation and healing. MATERIAL AND METHODS: In this experimental study 34 white, male, adult, Wistar rats, without middle ear disease were submited to anesthesia with ketamine 27 mg/kg and xylazine 2,7 mg/kg. Incisional myringotomy was done on the right ear, while laser myringotomy was done on the left. Myringotomies were evaluated periodically until healing. RESULTS: The healing

  1. Gene expression profiles in primary duodenal chick cells following transfection with avian influenza virus H5 DNA plasmid encapsulated in silver nanoparticles

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    Jazayeri SD

    2013-02-01

    Full Text Available Seyed Davoud Jazayeri,1 Aini Ideris,1,2 Kamyar Shameli,3 Hassan Moeini,1 Abdul Rahman Omar1,21Institute of Bioscience, 2Faculty of Veterinary Medicine, 3Faculty of Science, Universiti Putra Malaysia, Serdang, Selangor, MalaysiaAbstract: In order to develop a systemically administered safe and effective nonviral gene delivery system against avian influenza virus (AIV that induced cytokine expression, the hemagglutinin (H5 gene of AIV, A/Ck/Malaysia/5858/04 (H5N1 and green fluorescent protein were cloned into a coexpression vector pIRES (pIREGFP-H5 and formulated using green synthesis of silver nanoparticles (AgNPs with poly(ethylene glycol and transfected into primary duodenal cells taken from 18-day-old specific-pathogen-free chick embryos. The AgNPs were prepared using moderated temperature and characterized for particle size, surface charge, ultraviolet-visible spectra, DNA loading, and stability. AgNPs and AgNP-pIREGFP-H5 were prepared in the size range of 13.9 nm and 25 nm with a positive charge of +78 ± 0.6 mV and +40 ± 6.2 mV, respectively. AgNPs with a positive surface charge could encapsulate pIREGFP-H5 efficiently. The ultraviolet-visible spectra for AgNP-pIREGFP-H5 treated with DNase I showed that the AgNPs were able to encapsulate pIREGFP-H5 efficiently. Polymerase chain reaction showed that AgNP-pIREGFP-H5 entered into primary duodenal cells rapidly, as early as one hour after transfection. Green fluorescent protein expression was observed after 36 hours, peaked at 48 hours, and remained stable for up to 60 hours. In addition, green fluorescent protein expression generally increased with increasing DNA concentration and time. Cells were transfected using Lipocurax in vitro transfection reagent as a positive control. A multiplex quantitative mRNA gene expression assay in the transfected primary duodenal cells via the transfection reagent and AgNPs with pIREGFP-H5 revealed expression of interleukin (IL-18, IL-15, and IL-12

  2. The efficacy of nebulized magnesium sulfate alone and in combination with salbutamol in acute asthma

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    Sarhan HA

    2016-06-01

    Full Text Available Hatem A Sarhan,1 Omar H EL-Garhy,1 Mohamed A Ali,2 Nouran A Youssef1 1Department of Pharmaceutics, Faculty of Pharmacy, 2Department of Chest Diseases, Faculty of Medicine, Minia University, Minia, Egypt Objective: Evaluation of the efficacy of nebulized magnesium sulfate (MgSO4 alone and in combination with salbutamol in acute asthma.Methods: A double-blind randomized controlled study was conducted in Chest and Emergency Departments. Thirty patients of acute attack of bronchial asthma were randomized into three groups: MgSO4 nebulization (group A, salbutamol nebulization (group B, and their combination (group C. All patients were monitored before and after nebulization (each 20 minutes for peak expiratory flow rate (PEFR, respiratory rate (RR, heart rate (HR, blood pressure, pulsus paradoxus, oxygen saturation, clinical examination, and Fischl index.Results: A highly significant improvement in PEFR, PEFR percentage, and Fischl index and significant decrease in RR and HR was observed in all groups. A similar improvement in PEFR was observed in group A and group B (P=0.389. The difference in peak expiratory flow (PEF improvement was insignificant between group B and group C (P=0.101, while there was a significant differ­ence between group A and group C (P=0.014 in favor of group C.Conclusion: Nebulized MgSO4 alone or combined with salbutamol has a clinically significant bronchodilator effect in acute asthma and leads to clinical improvement, increase in PEFR, reduction in HR, and reduction in RR. The response to nebulized MgSO4 alone (PEFR improvement 54±35.6 L/min, P=0.001 is comparable (P=0.389 to that of nebulized salbutamol (PEFR improvement 67.0±41.9 L/min, P=0.001 and is significantly less than (P=0.014 that of nebulized combination (PEFR improvement 92.0±26.9 L/min, P=0.000. Keywords: nebulized magnesium sulfate, salbutamol, acute asthma, peak expiratory flow rate, Fischl index

  3. Factors associated with lipid goal attainment among acute coronary syndrome patients

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    Mohd-Zulkefli SZ

    2016-08-01

    Full Text Available Siti-Zainora Mohd-Zulkefli, Marhanis-Salihah Omar, Adyani Md-Redzuan Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia Background: The incidence of acute coronary syndrome (ACS, one of the most common cardiovascular diseases, is high. Lipid goal attainment is one of the important factors to reduce the risk of recurrent heart attack. Identification of factors influencing lipid goal attainment such as age, female, race, underlying comorbidities, intensity of lipid-lowering therapy, patients’ knowledge, and patients’ belief about medicine would be beneficial in achieving the lipid goal. This study is aimed to determine lipid profile attainment and prescribing pattern of lipid-lowering therapy as well as to identify factors influencing lipid profile attainment among ACS patients.Patients and methods: This researcher-assisted cross-sectional survey was carried out at a cardiology clinic in a tertiary hospital from March to May 2015.Results: A total of 101 ACS patients were involved in this study. The mean values for low-density lipoprotein cholesterol (LDL-C and high-density lipoprotein cholesterol levels were 2.75 (0.82 mmol/L and 1.14 (0.27 mmol/L, respectively, while the median value for triglyceride level was 2.75 (0.82 mmol/L. Only 15.8% of our participants achieved the targeted LDL-C. Simvastatin 20 mg was the most common regimen prescribed. Predictors for better LDL-C attainment were younger age (β=-0.228; P=0.032 and higher knowledge score (β=-0.255; P=0.049, while predictors for high-density lipoprotein cholesterol attainment were male (β=0.268; P=0.006, smoking (β=-0.192; P=0.045, and higher knowledge score (β=-0.195; P=0.039. Smoking (β=-0.361; P<0.0001 was the only predictor for higher triglyceride level.Conclusion: Younger age, female, lower knowledge score, and smoking status are good predictors for lipid attainment among ACS patients. Keywords: influence, disease, drug use, patient 

  4. A multicenter controlled study for dementia prevention through physical, cognitive and social activities – GESTALT-kompakt

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    Streber A

    2017-12-01

    Full Text Available Anna Streber, Karim Abu-Omar, Christian Hentschke, Alfred Rütten Department of Sport Science and Sport, Faculty of Humanities, Social Sciences, and Theology, Friedrich-Alexander-University of Erlangen-Nürnberg, Erlangen, Germany Abstract: Prevention of dementia is a public health priority. Physical activity (PA can reduce the risk of dementia, but the majority of people remain sedentary. We conducted a multicenter controlled study with older adults (60+ years. We hypothesized that an evidence-based PA intervention – GEhen, Spielen und Tanzen Als Lebenslange Tätigkeiten – kompakt [walking, playing and dancing as lifelong activities-compact] (GESTALT-kompakt – would lead to significantly larger improvements in PA levels (step counts/Fitbit Zip™, cognitive functions (DemTect and social activities (Social Activity Log, compared to an active control group. Data were collected at baseline and after 3 and 12 months. The intervention group received a 12-week (1/week multimodal and multicomponent PA program, which combined PA with cognitive and social activities. The control group received either regular gymnastics or cognitive training (1/week. A mixed linear model was chosen for analysis. A total of 87 older individuals were recruited in the GESTALT-kompakt study (68 females, average age =76.0 years, SD ±9.2, range 52–95 years. Marginally significant differences were observed in the intervention group (n=57 in comparison to the control group (n=30, regarding improvements in PA (difference of mean changes =866.4 steps, p=0.055 after 3 months. However, their PA decreased to the baseline score value after 12 months (-866.0 steps, p=0.061. GESTALT-kompakt did not cause significant differences in cognitive functioning (-0.8620, p=0.074 and social activities (-0.2428, p=0.288 in comparison to the control intervention from T0 to T1. Sixteen (24.2% study participants who finished T2 reported a negative life event during the follow-up period

  5. Dose perturbation effect of metallic spinal implants in proton beam therapy.

    Science.gov (United States)

    Jia, Yingcui; Zhao, Li; Cheng, Chee-Wai; McDonald, Mark W; Das, Indra J

    2015-09-08

    The purpose of this study was to investigate the effect of dose perturbations for two metallic spinal screw implants in proton beam therapy in the perpendicular and parallel beam geometry. A 5.5 mm (diameter) by 45 mm (length) stainless steel (SS) screw and a 5.5 mm by 35 mm titanium (Ti) screw commonly used for spinal fixation were CT-scanned in a hybrid phantom of water and solid water. The CT data were processed with an orthopedic metal artifact reduction (O-MAR) algorithm. Treatment plans were generated for each metal screw with a proton beam oriented, first parallel and then perpendicular, to the longitudinal axis of the screw. The calculated dose profiles were compared with measured results from a plane-parallel ion chamber and Gafchromic EBT2 films. For the perpendicular setup, the measured dose immediately downstream from the screw exhibited dose enhancement up to 12% for SS and 8% for Ti, respectively, but such dose perturbation was not observed outside the lateral edges of the screws. The TPS showed 5% and 2% dose reductions immediately at the interface for the SS nd Ti screws, respectively, and up to 9% dose enhancements within 1 cm outside of the lateral edges of the screws. The measured dose enhancement was only observed within 5 mm from the interface along the beam path. At deeper depths, the lateral dose profiles appeared to be similar between the measurement and TPS, with dose reduction in the screw shadow region and dose enhancement within 1-2 cm outside of the lateral edges of the metals. For the parallel setup, no significant dose perturbation was detected at lateral distance beyond 3 mm away from both screws. Significant dose discrepancies exist between TPS calculations and ion chamber and film measurements in close proximity of high-Z inhomogeneities. The observed dose enhancement effect with proton therapy is not correctly modeled by TPS. An extra measure of caution should be taken when evaluating dosimetry with spinal metallic implants.

  6. Users’ perspectives on Implanon in Malaysia, a multicultural Asian country

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    Asmah Mastor

    2011-02-01

    Full Text Available Asmah Mastor, Si Lay Khaing, Siti Zawiah Omar Department of Obstetrics and Gynaecology, University of Malaya, Kuala Lumpur, MalaysiaBackground: The primary objective of this study was to evaluate Malaysian women’s ¬perception, acceptance, and views on Implanon® as a contraceptive method. We also aimed to identify women who favor Implanon, their vaginal bleeding patterns, nonmenstrual adverse events, reasons for discontinuation, and effect of Implanon on breastfeeding.Study design: This study followed up 140 women after insertion of Implanon at the University of Malaya Medical Centre by examination of their medical records and telephone interviews. User profile, discontinuation rate, reasons for choice of Implanon, discontinuation, menstrual and nonmenstrual side effects, and satisfaction rate were assessed.Results: The average age of users was 34.7 years, and 94.2% were para 2 and above. The ethnic distribution of the women reflected that of the general Malaysian population. The majority had at least secondary education (94.2%, with 41.2% having a higher degree. All of the users reported that they chose Implanon because it does not need compliance, and 72.1% felt that Implanon was cost-effective in the long term. Most users (70% reported irregular menses and this was the main reason given for discontinuation. The vast majority reported an overall decrease in menstrual blood loss. Almost half (46% suffered prolonged bleeding/spotting, and infrequent bleeding was experienced by 71 users (50.7%. Half of the women did not experience any nonmenstrual adverse events. The commonest complaint was weight gain, with the next most common complaints being hair loss, acne, headache, nausea, mood swings, and reduced libido. Most of the nursing mothers denied a reduction in breast milk. There was a high mean satisfaction score with Implanon.Conclusion: Implanon is well accepted by Malaysian women despite a high incidence of irregular bleeding which was

  7. Perception of academic stress among Health Science Preparatory Program students in two Saudi universities

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    Alsulami S

    2018-03-01

    Full Text Available Saleh Alsulami, Zaid Al Omar, Mohammed S Binnwejim, Fahad Alhamdan, Amr Aldrees, Abdulkarim Al-bawardi, Meshary Alsohim, Mohammed Alhabeeb Departments of Family Medicine and Medical Education, College of Medicine, Imam Mohammad ibn Saud Islamic University, Riyadh, Saudi Arabia Abstract: The Health Science Preparatory Program (HSPP is a special program that aims to enhance the educational preparedness of students for participation in a health sciences career. Students spend their first university year in a combined extensive teaching program before they can be assigned to a particular health science specialty. It is thought that students enrolled in a highly competitive environment such as HSPP with a long list of potential stressors, including developmental, academic overload, language barriers and competition, are more disposed to stress and stress-related complications. This study aims to measure the level of academic stress and to determine its risk factors in students enrolled in HSPP-adapted local universities in Saudi Arabia. The study was conducted at two Saudi universities, King Saud University (KSU and Imam Mohammad ibn Saud Islamic University (IMSU with competition-based and non-competition-based HSPP learning models, respectively. Both universities adopt the HSPP system. The scale for assessing academic stress (SAAS was used to assess students’ perceived stress. A total of 290 students successfully completed the questionnaire (N=290, with a mean age of 18.66 years. Mean SAAS scores for KSU and IMSU students were 8.37 (SD = 4.641 and 7.97 (SD = 5.104, P=0.480, respectively. Only “satisfaction” and “associated social and health problems” have shown statistically significant correlation with university (P=0.000 and P=0.049, respectively. This study has found mean SAAS score for two local universities with competition-based versus non-competition-based HSPP learning models. Academic stress correlation with age, gender and

  8. Rethinking Deterrence: The International Criminal Court in Sudan

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    Pablo Castillo

    2007-01-01

    Full Text Available El 1 de Abril del 2005, el Consejo de Seguridad de las Naciones Unidas remitió la situación de Darfur (Sudán al Tribunal Penal Internacional. Dos meses más tarde, el Fiscal aceptó la remisión y decidió iniciar una investigación. No se trata sólo del primer caso enviado a la Corte por las Naciones Unidas; se trata además de la primera instancia en la que el TPI se ve involucrado en un país cuyo gobierno se opone tajantemente a cooperar con el tribunal y rechaza su jurisdicción. ¿Cómo se desenvolverá esta recién creada institución en un entorno político tan complicado? ¿Probará este caso que el derecho penal internacional puede disuadir la comisión de atrocidades? ¿Puede el escrutinio de la comunidad internacional y la amenaza de acusaciones judiciales inhibir la conducta de del Presidente de Sudán, Omar al-Bashir? Este artículo sugiere que excesivo énfasis en la disuasión como elemento central, tan prevalente en la literatura que vincula el Derecho Internacional con la resolución de conflictos, tiene poco valor analitico y no ayuda a la causa de la justicia internacional. Críticos y escépticos, cada vez mas numerosos en el mundo anglosajón, pasan por alto la diferencia entre disuasión a corto plazo y prevención a largo plazo, ignoran la importancia de la credibilidad y la consistencia como funciones necesarias de la disuasión, y no tienen en cuenta la variedad de estrategias que los actores internacionales eligen para plantarle cara a la amenaza de acusaciones judiciales, así como las restricciones que limitan sus acciones y sus opciones de salida.

  9. Physician adherence to hypertension treatment guidelines and drug acquisition costs of antihypertensive drugs at the cardiac clinic: a pilot study

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    Abdulameer SA

    2012-01-01

    Full Text Available Shaymaa Abdalwahed Abdulameer1, Mohanad Naji Sahib1, Noorizan Abd Aziz1,2, Yahaya Hassan1,2, Hadeer Akram Abdul AlRazzaq1, Omar Ismail31School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 Minden, Penang, Malaysia; 2Faculty of Pharmacy, Universiti Teknologi MARA (UiTM, 42300 Puncak Alam, Selangor, Malaysia; 3Hospital Pulau Pinang, 10900, Penang, MalaysiaAbstract: Prescribing pattern surveys are one of the pharmacoepidemiological techniques that provide an unbiased picture of prescribing habits. Prescription surveys permit the identification of suboptimal prescribing patterns for further evaluation. The aims of this study were to determine the prescribing trend, adherence of the prescribers to the guideline, and the impact of drug expenditure on drug utilization at the cardiac clinic of Penang Hospital, Malaysia. This was a cross-sectional study. Demographic data of the patients, diagnoses and the drugs prescribed were recorded. The average drug acquisition costs (ADAC were calculated for each antihypertensive drug class on a daily and annual basis. Adherence to the guideline was calculated as a percentage of the total number of patients. A total of 313 individuals fulfilled the inclusion criteria. The average age of the study population was 59.30 ± 10.35 years. The mean number of drugs per prescription in the study was 2.09 ± 0.78. There were no significant differences in the demographic data. Antihypertensive drugs were used in monotherapy and polytherapy in 20.8% and 79.2% of the patients, respectively. Adherence to the guideline regarding prescription occurred in 85.30% of the patients. The lowest priced drug class was diuretics and the highest was angiotensin-receptor blockers. In conclusion, the total adherence to the guideline was good; the adherence percentage only slightly decreased with a co-existing comorbidity (such as diabetes mellitus. The use of thiazide diuretics was encouraged because they are well tolerated and

  10. Association of ADIPOQ +45T>G polymorphism with body fat mass and blood levels of soluble adiponectin and inflammation markers in a Mexican-Mestizo population

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    Guzman-Ornelas MO

    2012-10-01

    Full Text Available Milton-Omar Guzman-Ornelas,1 Efrain Chavarria-Avila,1 Jose-Francisco Munoz-Valle,1,2 Laura-Elizabeth Armas-Ramos,3 Jorge Castro-Albarran,3,4 Maria Elena Aguilar Aldrete,1,5 Edith Oregon-Romero,2 Monica Vazquez-Del Mercado,2 Rosa-Elena Navarro-Hernandez1–31Biomedical Sciences Doctorate Program, 2Department of Molecular Biology and Genomics, 3Master of Human Nutrition Program, University of Guadalajara, Guadalajara, Jalisco, México; 4HMIELM, Secretaria de Salud Jalisco, Guadalajara, Jalisco, Mexico; 5Department of Public Health, University of Guadalajara, Jalisco, MéxicoPurpose: Obesity is a disease with genetic susceptibility characterized by an increase in storage and irregular distribution of body fat. In obese patients, the decrease in the Adiponectin gene (ADIPOQ expression has been associated with a systemic low-grade inflammatory state. Our aim was to investigate the relationship between ADIPOQ +45T>G gene simple nucleotide polymorphism (SNP rs2241766 with serum adiponectin (sAdiponectin, distribution of body fat storage, and inflammation markers.Subjects and methods: In this cross-sectional study, 242 individuals from Western Mexico characterized as Mexican-Mestizo and classified by body mass index (BMI, were included. Anthropometrics, body composition, body fat distribution, and inflammation markers were measured by routine methods. Genotypes were characterized using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP technique and sAdiponectin by the ELISA method. A P-value <0.05 was considered the statistically significant threshold.Results: sAdiponectin is associated with BMI (P < 0.001 and the genotypes (P < 0.001 to 0.0046 GG (8169 ± 1162 ng/mL, TG (5189 ± 501 ng/mL, and TT (3741 ± 323 ng/mL, but the SNP ADIPOQ +45T.G is not associated with BMI. However, the detailed analysis showed association of this SNP with a pattern of fat distribution and correlations (P < 0.05 with inflammation markers and

  11. Pre-emptive multimodal analgesia with tramadol and ketamine–lidocaine infusion for suppression of central sensitization in a dog model of ovariohysterectomy

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    Kaka U

    2018-04-01

    Full Text Available Ubedullah Kaka,1,2 Nor-Alimah Rahman,1 Adamu Abdul Abubakar,1,3 Yong Meng Goh,2,4 Sharida Fakurazi,5,6 Mohamed Ariff Omar,4 Hui Cheng Chen1 1Department of Companion Animal Medicine and Surgery, Faculty of Veterinary Medicine, 2Institute of Tropical Agriculture and Food Security, Universiti Putra Malaysia, Serdang, Malaysia; 3Department of Veterinary Surgery and Radiology, Usmanu Danfodiyo University, Sokoto, Nigeria; 4Department of Preclinical Veterinary Sciences, Faculty of Veterinary Medicine, 5Laboratory of Vaccines and Immunotherapeutics, Institute of Bioscience, 6Department of Human Anatomy, Faculty of Medicine and Health Science, Universiti Putra Malaysia, Serdang, Malaysia Objectives: The effects of pre-emptive infusion of ketamine–lidocaine with tramadol on the suppression of central sensitization were investigated in a dog ovariohysterectomy model.Patients and methods: Twelve dogs were randomly assigned to two groups: ketamine–­lidocaine–tramadol (KLT and tramadol (T groups. Both groups received intravenous tramadol 4 mg/kg body weight as premedication. Immediately after induction, the KLT group received ketamine and lidocaine at 0.5 and 2 mg/kg loading dose, followed by continuous rate infusion of 50 and 100 µg/kg/min, respectively, for 2 hours. Dogs in T group received saline bolus and continuous rate infusion at equi-volume. Intraoperatively, hemodynamic responses to surgical stimulation were recorded, whereas postoperative pain was evaluated using an algometer and short form of the Glasgow composite measure pain scale.Results: Intraoperatively, hemodynamic responses to surgical stimulation were obtunded to a greater degree in KLT compared to T group. Postoperatively, the pain scores increased only for the first hour in KLT group, compared to 12 hours in T group. Mechanical thresholds at the abdomen decreased postoperatively between 12 and 60 hours in KLT group versus the entire 72 hours in T group. Thresholds at tibia and

  12. PREFACE: X Workshop of the Gravitation and Mathematical Physics Division, Mexican Physical Society

    Science.gov (United States)

    2014-11-01

    Avanzados (CINVESTAV), Universidad Autónoma Metropolitana Iztapalapa (UAM-I), Universidad de Guanajuato (UG), Universidad Nacional Autónoma de México (UNAM). We especially acknowledge the support and the kind hospitality of our host, the Universidad Autónoma del Estado de Hidalgo. Ricardo Becerril Bárcenas, Héctor H. Hernández Hernández, Miguel Sabido, Carlos A. Soto, Luis Alberto López, Omar Pedraza, Victoria E. Cerón. Editors

  13. In vivo antitumor and antimetastatic effects of flavokawain B in 4T1 breast cancer cell-challenged mice

    Directory of Open Access Journals (Sweden)

    Abu N

    2015-03-01

    Full Text Available Nadiah Abu,1,2 Nurul Elyani Mohamed,2 Swee Keong Yeap,3 Kian Lam Lim,4 M Nadeem Akhtar,5 Aimi Jamil Zulfadli,3 Beh Boon Kee,2 Mohd Puad Abdullah,2 Abdul Rahman Omar,3 Noorjahan Banu Alitheen2 1Bright Sparks Unit, Universiti Malaya, Kuala Lumpur, Malaysia; 2Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, 3Institute of Bioscience, Universiti Putra Malaysia, Serdang, Selangor Darul Ehsan, Malaysia; 4Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Lot PT, Jalan Sungai Long, Bandar Sungai Long, Cheras, Selangor, Malaysia; 5Faculty of Industrial Sciences and Technology, Universiti Malaysia Pahang, Lebuhraya Tun Razak, Kuantan Pahang, Malaysia Abstract: Flavokawain B (FKB is a naturally occurring chalcone that can be isolated through the root extracts of the kava-kava plant (Piper methysticum. It can also be synthesized chemically to increase the yield. This compound is a promising candidate as a biological agent, as it is reported to be involved in a wide range of biological activities. Furthermore, FKB was reported to have antitumorigenic effects in several cancer cell lines in vitro. However, the in vivo antitumor effects of FKB have not been reported on yet. Breast cancer is one of the major causes of cancer-related deaths in the world today. Any potential treatment should not only impede the growth of the tumor, but also modulate the immune system efficiently and inhibit the formation of secondary tumors. As presented in our study, FKB induced apoptosis in 4T1 tumors in vivo, as evidenced by the terminal deoxynucleotidyl transferase dUTP nick end labeling and hematoxylin and eosin staining of the tumor. FKB also regulated the immune system by increasing both helper and cytolytic T-cell and natural killer cell populations. In addition, FKB also enhanced the levels of interleukin 2 and interferon gamma but suppressed interleukin 1B. Apart from that, FKB was also found to inhibit

  14. Applying theory of planned behavior to predict exercise maintenance in sarcopenic elderly

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    Ahmad MH

    2014-09-01

    Full Text Available Mohamad Hasnan Ahmad,1 Suzana Shahar,2 Nur Islami Mohd Fahmi Teng,2 Zahara Abdul Manaf,2 Noor Ibrahim Mohd Sakian,3 Baharudin Omar41Centre of Nutrition Epidemiology Research, Institute of Public Health, Ministry of Health, Kuala Lumpur, Malaysia; 2Dietetics Program, 3Occupational Therapy Program, 4Department of Biomedical Sciences, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia Abstract: This study aimed to determine the factors associated with exercise behavior based on the theory of planned behavior (TPB among the sarcopenic elderly people in Cheras, Kuala ­Lumpur. A total of 65 subjects with mean ages of 67.5±5.2 (men and 66.1±5.1 (women years participated in this study. Subjects were divided into two groups: 1 exercise group (n=34; 25 men, nine women; and 2 the control group (n=31; 22 men, nine women. Structural equation modeling, based on TPB components, was applied to determine specific factors that most contribute to and predict actual behavior toward exercise. Based on the TPB’s model, attitude (ß=0.60 and perceived behavioral control (ß=0.24 were the major predictors of intention to exercise among men at the baseline. Among women, the subjective norm (ß=0.82 was the major predictor of intention to perform the exercise at the baseline. After 12 weeks, attitude (men’s, ß=0.68; women’s, ß=0.24 and subjective norm (men’s, ß=0.12; women’s, ß=0.87 were the predictors of the intention to perform the exercise. “Feels healthier with exercise” was the specific factor to improve the intention to perform and to maintain exercise behavior in men (ß=0.36 and women (ß=0.49. “Not motivated to perform exercise” was the main barrier among men’s intention to exercise. The intention to perform the exercise was able to predict actual behavior regarding exercise at the baseline and at 12 weeks of an intervention program. As a conclusion, TPB is a useful model to determine and

  15. The cut-off values of anthropometric variables for predicting mild cognitive impairment in Malaysian older adults: a large population based cross-sectional study

    Directory of Open Access Journals (Sweden)

    Won H

    2017-02-01

    Full Text Available Huiloo Won,1 Zahara Abdul Manaf,2 Arimi Fitri Mat Ludin,3 Mohd Azahadi Omar,4 Rosdinom Razali,5 Suzana Shahar2 1Nutrition Program, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, 2Dietetics Program, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, 3Biomedical Science Program, School of Diagnostic and Applied Health Sciences, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, 4Centre for Burden of Disease Research, Institute for Public Health, Ministry of Health Malaysia, 5Department of Psychiatry, Faculty of Medicine, Hospital Canselor Tuanku Muhriz, University Kebangsaan Malaysia, Kuala Lumpur, Malaysia Purpose: Older adults are at risk of mild cognitive impairment (MCI, and simple anthropometric measurements can be used to screen for this condition. Thus, the aim of this study was to explore the cut-off values of body mass index (BMI and waist circumference (WC for predicting the risk of MCI in older Malaysian adults.Methods: A total of 2,240 Malaysian older adults aged ≥60 years were recruited using multistage random sampling in a population based cross-sectional study. Receiver operating characteristic (ROC curve was used to determine the cut-off values of BMI and WC with optimum sensitivity and specificity for the detection of MCI. Age, gender, years of education, smoking habit, alcohol consumption, depression, and medical conditions were used as confounding factors in this analysis.Results: A BMI cut-off value of 26 kg/m2 (area under the receiver operating characteristic curve [AUC] 0.725; sensitivity 90.5%; specificity 38.8% was appropriate in identifying the risk of getting MCI in both men and women. The optimum WC cut-offs for likelihood of MCI were 90 cm (AUC 0.745; sensitivity 78.0%; specificity 59.8% for men and 82 cm (AUC 0.714; sensitivity 84.3%; specificity 49.7% for women. The optimum calf circumference (CC cut-off values for identifying MCI were 29 cm (AUC 0.731; sensitivity 72.6%; specificity

  16. PREFACE: 12th Conference on ''Theoretical Nuclear Physics in Italy''

    Science.gov (United States)

    Bombaci, I.; Covello, A.; Marcucci, L. E.; Rosati, S.

    2009-07-01

    These Proceedings contain the invited and contributed papers presented at the 12th Conference on Theoretical Nuclear Physics in Italy held in Cortona, Italy, from 8-10 October 2008. As usual, the meeting was held at il Palazzone, a 16th century castle owned by the Scuola Normale Superiore di Pisa. The aim of this biennal conference is to bring together Italian theorists working in various fields of Nuclear Physics to discuss their latest results and confront their points of view in a lively and informal way. This offers the opportunity to promote collaborations between different groups. There were about 50 participants at the conference, coming from 14 Italian Universities (Cagliari, Catania, Ferrara, Firenze, Genova, Lecce, Milano, Napoli, Padova, Pavia, Pisa, Roma, Trento, Trieste). The program of the conference, prepared by the Organizing Committee (Ignazio Bombaci, Aldo Covello, Laura Elisa Marcucci and Sergio Rosati) focused on six main topics: Few-Nucleon Systems, Nuclear Matter and Nuclear Dynamics, Nuclear Astrophysics, Structure of Hadrons and Hadronic Matter, Nuclear Structure, Nuclear Physics with Electroweak Probes. Winfried Leidemann, Maria Colonna, Marcello Lissia, Elena Santopinto, Silvia Lenzi and Omar Benhar took the burden of giving general talks on these topics and reviewing the research activities of the various Italian groups. In addition, 19 contributed papers were presented, most of them by young participants. In the last session of the Conference there were two invited talks related to experimental activities of great current interest. Gianfranco Prete from the Laboratori Nazionali di Legnaro spoke about the Italian radioactive ion beam facility SPES and the status of the European project EURISOL, while Nicola Colonna from the INFN, Bari, gave an overview of the perspectives of development of fourth-generation nuclear reactors. We would like to thank the authors of the general reports for their hard work in reviewing the main achievements in

  17. Assessment of ischemia in acute central retinal vein occlusion from inner retinal reflectivity on spectral domain optical coherence tomography

    Directory of Open Access Journals (Sweden)

    Browning DJ

    2016-12-01

    Full Text Available David J Browning, Omar S Punjabi, Chong Lee Department of Ophthalmology, Charlotte Eye, Ear, Nose and Throat Associates, P.A., Charlotte, NC, USA Purpose: To determine the relationship between different spectral domain optical coherence tomography (SD-OCT signs of retinal ischemia in acute central retinal vein occlusion (CRVO and whether they predict anterior segment neovascularization (ASNV.Design: Retrospective, observational study.Subjects: Thirty-nine consecutive patients with acute CRVO and 12 months of follow-up.Methods: We graded baseline SD-OCTs for increased reflectivity of the inner retina, loss of definition of inner retinal layers, presence of a prominent middle-limiting membrane (p-MLM sign, and presence of paracentral acute middle maculopathy (PAMM. Graders were masked with respect to all clinical information.Results: The intraclass correlation coefficients (ICCs of grading–regrading by graders 1 and 2 were 0.8104, 95% confidence interval (CI (0.6686, 0.8956, and 0.7986, 95% CI (0.6475, 0.8892, respectively. The intragrader coefficients of repeatability (COR for graders 1 and 2 were 0.94 and 0.92, respectively. The ICC of graders 1 compared with 2 was 0.8039, 95% CI (0.6544, 0.8916. The intergrader COR was 0.80. SD-OCT grades of baseline ischemia were not associated with baseline visual acuity (VA, central subfield mean thickness (CSMT, or relative afferent pupillary defect; 12-month VA, CSMT, change in VA, change in CSMT, number of antivascular endothelial growth factor injections or corticosteroid injections, or proportion of eyes developing ASNV. SD-OCT grades of ischemia did not correlate with the proportion of eyes having the p-MLM sign or PAMM. PAMM and p-MLM are milder signs of ischemia than increased reflectivity of the inner retinal layers. Eyes with PAMM can evolve, losing PAMM and gaining the p-MLM sign.Conclusion: Grading of ischemia from SD-OCT in acute CRVO was repeatable within graders and reproducible across

  18. Cationized dextran nanoparticle-encapsulated CXCR4-siRNA enhanced correlation between CXCR4 expression and serum alkaline phosphatase in a mouse model of colorectal cancer

    Directory of Open Access Journals (Sweden)

    Abedini F

    2012-07-01

    Full Text Available Fatemeh Abedini,1 Hossein Hosseinkhani,2 Maznah Ismail,1,3 Abraham J Domb,4 Abdul Rahman Omar,1,5 Pei Pei Chong,1,2 Po-Da Hong,3 Dah-Shyong Yu,6 Ira-Yudovin Farber41Laboratory of Molecular Biomedicine, Institute of Bioscience, Universiti Putra Malaysia, Selangor, 2Graduate Institute of Biomedical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan, 3Faculty of Medicine & Health Sciences, Universiti Putra Malaysia, Selangor, Malaysia, 4Institute of Drug Research, The Center for Nanoscience and Nanotechnology, School of Pharmacy-Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel, 5Faculty of Veterinary Medicine, Universiti Putra Malaysia, Selangor, Malaysia, 6Nanomedicine Research Center, National Defense Medical Center, Taipei, TaiwanPurpose: The failure of colorectal cancer treatments is partly due to overexpression of CXCR4 by tumor cells, which plays a critical role in cell metastasis. Moreover, serum alkaline phosphatase (ALP levels are frequently elevated in patients with metastatic colorectal cancer. A polysaccharide, dextran, was chosen as the vector of siRNA. Spermine was conjugated to oxidized dextran by reductive amination process to obtain cationized dextran, so-called dextran-spermine, in order to prepare CXCR4-siRNAs/dextran-spermine nanoparticles. The fabricated nanoparticles were used in order to investigate whether downregulation of CXCR4 expression could affect serum ALP in mouse models of colorectal cancer.Methods: Colorectal cancer was established in BALB/C mice following injection of mouse colon carcinoma cells CT.26WT through the tail vein. CXCR4 siRNA for two sites of the target gene was administered following injection of naked siRNA or siRNA encapsulated into nanoparticles.Results: In vivo animal data revealed that CXCR4 silencing by dextran-spermine nanoparticles significantly downregulated CXCR4 expression compared with naked CXCR4 siRNA. Furthermore, there was

  19. Abdominal sacrocolpopexy with Pelvicol xenograft and concomitant Burch colposuspension

    Directory of Open Access Journals (Sweden)

    Hijazi S

    2017-09-01

    Full Text Available Sameh Hijazi,1,2 Dieter Echtle,3 Omar M Aboumarzouk,4 Elmar Heinrich2,5 1Department of Urology, Klinikum Ibbenbüeren, Ibbenbüeren, 2Department of Urology, University Medical Center, Goettingen, 3Department of Urology, Städtische Kliniken Mönchengladbach, Mönchengladbach, Germany; 4Urology Department, Newport, Wales, UK; 5Department of Urology, Klinikum Wels-Grieskirchen, Standort Wels, Austria Purpose: To evaluate the efficacy of Pelvicol xenograft use during abdominal sacrocolpopexy to repair pelvic organ prolapse (POP.Patients and methods: A total of 27 consecutive women with symptomatic POP were included in this study. A POP-quantification system and International Continence Society classification were used. Functional and anatomical outcomes were assessed. Subjective outcomes and physical activity after surgery were evaluated due to modified quality of life questionnaire.Results: Median follow-up was 21 months (range: 16 to 41 months. Twenty-four (89% patients were available for anatomical and subjective evaluation. Preoperative POP- quantification classification was: stage I: 11.1%, stage II: 25.9%, stage III: 48.2%, and stage IV: 14.8%. Overall, pad usage significantly decreased (mean 4.8 vs 1 pads, P=0.001. Stress urinary incontinence significantly improved after surgery in nine women (P=0.001. An additional five women were completely continent. No de-novo incontinence developed. Six women with preoperative urinary retention improved in the amount of residual urine postoperative (mean 35 vs 165 mL. Failure rate was 8.3% at 3 and 11 months after surgery, requiring a second reconstruction. There was no graft related complications or graft rejections necessitating removal occurring. Response rate of the questionnaire was 67%. Two women reported no interference in physical activity after 2 postoperative months, five women after 5 months, and five women 1 year later. Pelvic pain (vaginal pain was partly improved in eight patients

  20. Public Opinions Toward Diseases: Infodemiological Study on News Media Data.

    Science.gov (United States)

    Huang, Ming; ElTayeby, Omar; Zolnoori, Maryam; Yao, Lixia

    2018-05-08

    Zika virus were linked to other infectious diseases during 1996/1997 and 2016, respectively. The multi-dimensional analysis of news media data allows the discovery of focus, sentiments and topics of news media in terms of diseases and medical conditions. These infodemiological discoveries could shed light on unmet medical needs and research priorities for future and provide guidance for the decision making in public policy. ©Ming Huang, Omar ElTayeby, Maryam Zolnoori, Lixia Yao. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 08.05.2018.

  1. SU-E-T-329: Dosimetric Impact of Implementing Metal Artifact Reduction Methods and Metal Energy Deposition Kernels for Photon Dose Calculations

    International Nuclear Information System (INIS)

    Huang, J; Followill, D; Howell, R; Liu, X; Mirkovic, D; Stingo, F; Kry, S

    2015-01-01

    Purpose: To investigate two strategies for reducing dose calculation errors near metal implants: use of CT metal artifact reduction methods and implementation of metal-based energy deposition kernels in the convolution/superposition (C/S) method. Methods: Radiochromic film was used to measure the dose upstream and downstream of titanium and Cerrobend implants. To assess the dosimetric impact of metal artifact reduction methods, dose calculations were performed using baseline, uncorrected images and metal artifact reduction Methods: Philips O-MAR, GE’s monochromatic gemstone spectral imaging (GSI) using dual-energy CT, and GSI imaging with metal artifact reduction software applied (MARs).To assess the impact of metal kernels, titanium and silver kernels were implemented into a commercial collapsed cone C/S algorithm. Results: The CT artifact reduction methods were more successful for titanium than Cerrobend. Interestingly, for beams traversing the metal implant, we found that errors in the dimensions of the metal in the CT images were more important for dose calculation accuracy than reduction of imaging artifacts. The MARs algorithm caused a distortion in the shape of the titanium implant that substantially worsened the calculation accuracy. In comparison to water kernel dose calculations, metal kernels resulted in better modeling of the increased backscatter dose at the upstream interface but decreased accuracy directly downstream of the metal. We also found that the success of metal kernels was dependent on dose grid size, with smaller calculation voxels giving better accuracy. Conclusion: Our study yielded mixed results, with neither the metal artifact reduction methods nor the metal kernels being globally effective at improving dose calculation accuracy. However, some successes were observed. The MARs algorithm decreased errors downstream of Cerrobend by a factor of two, and metal kernels resulted in more accurate backscatter dose upstream of metals. Thus

  2. Novel N-substituted aminobenzamide scaffold derivatives targeting the dipeptidyl peptidase-IV enzyme

    Directory of Open Access Journals (Sweden)

    Al-Balas QA

    2014-01-01

    Full Text Available Qosay A Al-Balas,1 Munia F Sowaileh,1 Mohammad A Hassan,1 Amjad M Qandil,1,2 Karem H Alzoubi,3 Nizar M Mhaidat,3 Ammar M Almaaytah,4 Omar F Khabour51Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan; 2Pharmaceutical Sciences Department, College of Pharmacy, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia; 3Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan; 4Department of Pharmaceutical Technology, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan; 5Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, Jordan University of Science and Technology, Irbid, JordanBackground: The dipeptidyl peptidase-IV (DPP-IV enzyme is considered a pivotal target for controlling normal blood sugar levels in the body. Incretins secreted in response to ingestion of meals enhance insulin release to the blood, and DPP-IV inactivates these incretins within a short period and stops their action. Inhibition of this enzyme escalates the action of incretins and induces more insulin to achieve better glucose control in diabetic patients. Thus, inhibition of this enzyme will lead to better control of blood sugar levels.Methods: In this study, computer-aided drug design was used to help establish a novel N-substituted aminobenzamide scaffold as a potential inhibitor of DPP-IV. CDOCKER software available from Discovery Studio 3.5 was used to evaluate a series of designed compounds and assess their mode of binding to the active site of the DPP-IV enzyme. The designed compounds were synthesized and tested against a DPP-IV enzyme kit provided by Enzo Life Sciences. The synthesized compounds were characterized using proton and carbon nuclear magnetic resonance, mass spectrometry, infrared spectroscopy, and determination of melting point.Results: Sixty

  3. Cineastas afrodescendientes del siglo XXI, entre diáspora, transnacionalismo y post-racialidad / Filmmakers of African descent in the XXI century, between diaspora, transnationalism and post-raciality

    Directory of Open Access Journals (Sweden)

    Leonardo De Francheschi

    2016-03-01

    Full Text Available En los últimos quince años (2001-14, el cine diaspórico afrodescendiente ha crecido, aunque haya sido a través de modalidades diferentes, según los diferentes contextos nacionales. El creciente éxito de estrellas como Denzel Washington, Idris Elba o Omar Sy, junto a la irrupción en los Oscars de 2014 del director Steve McQueen, está facilitando el desarrollo de un nicho de público transnacional, formado sobre todo por jóvenes afrodescendientes cada vez más conscientes y deseosos de verse representados por personajes negros en papeles importantes. De Estados Unidos a Europa, estamos asistiendo al surgimiento de una sensibilidad más proactiva, flexible y pragmática por parte de directores afrodescendientes, que se mueven con distintas estrategias de política identitaria y de relación con la industria, pero con los mismos objetivos de empoderamiento. La referencia a la agenda nacional e identitaria, cuando está presente de una forma marcada, sí que tiende a construir una relación privilegiada con un público de referencia afrodescendiente, pero apuesta también por influir en el imaginario y el mercado mainstream. Llama la atención el intento de algunos de deshacerse de la hipoteca de un peso de la representación que sigue afectando a directores afrodescendientes, con la complicidad de una crítica cinematográfica que sigue interpretando la experiencia de los directores afrodiaspóricos desde una perspectiva discontinuista, excepcionalista, como expresión de una «comunidad imaginada», además, cada vez más difícil de circunscribir. Lo que me propongo es recorrer, de manera no sistemática, el trayecto que han realizado las personalidades afrodescendientes más significativas que emergieron o se confirmaron en el panorama cinematográfico durante el período examinado, con atención especial a Francia, Gran Bretaña y Estados Unidos.Palabras clave: Cine, diáspora, África, transnacionalismo, post

  4. The calembour in Rabbi Raphael Aharon Monsonego’s “Neot midbar”

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    Lavi, Tamar

    2015-06-01

    Full Text Available Rabbi Raphael Aharon Monsonego was a Moroccan rabbi who lived in the 18th-19th centuries. His literary creation is extensive, and apart from halachic texts he wrote a series of poems that are characterized by abundant use of the calembour technique. The calembour (in English, pun is a specific type of allusion used by North African Jewish poets and writers. Like all allusions it is based on “a meeting of two texts, one implicit – i.e., in our consciousness and memory, and the other explicit – i.e., in the actual text in front of us.” A calembour differs from other types of allusions in that it consists of “phonetic and spelling changes in the words, idioms and fragmented verses in order to gain a humorous effect and other associative allusion.” Namely, in the calembour a word or phrase from a biblical or rabbinic text is presented “with a minimal change in letter or vowel etc. […] creating a witticism or a new meaning.” The author assumes, then, that the reader is able to intuitively identify the original text despite the changes made and even enjoy and appreciate the linguistic witticism since he is well-versed in the Jewish sources (especially the Hebrew Bible and halachic literature. The aim of this paper is to examine the use of the calembour in Monsonego’s poetry through several examples of its different forms and especially through the analysis of one of the poems that features a larger use of this technique: “Im omar avo ha-‘ir” (‘If I resolve to arouse lament’.R. Raphael Aharón Monsonego fue un rabino marroquí que vivió entre los siglos XVIII y XIX. Su extensa obra literaria incluye textos religiosos de la Halajá, como también poemas que se caracterizan por el frecuente recurso a la técnica del calambur, por la cual hace referencia a versos bíblicos en un contexto diferente. El calambur es un artificio lingüístico, un tipo de alusión utilizada por poetas judíos del norte de África, que est

  5. Outcome of corneal transplantation in a private institution in Saudi Arabia

    Directory of Open Access Journals (Sweden)

    Omar N

    2013-06-01

    Full Text Available Nazri Omar,1,2 Charbel T Bou Chacra,1 Khalid F Tabbara1,3,4 1The Eye Center and The Eye Foundation for Research in Ophthalmology, Riyadh, Saudi Arabia; 2Department of Ophthalmology, Universiti Putra Malaysia, Serdang, Malaysia; 3Department of Ophthalmology, King Saud University, Riyadh, Saudi Arabia; 4The Wilmer Ophthalmological Institute of Johns Hopkins University School of Medicine, Baltimore, MD, USA Background: The aim of this work was to describe the indications, complications, and outcomes of penetrating keratoplasty (PKP in Saudi Arabia. Methods: In a retrospective, noncomparative interventional case series, the medical records of patients who underwent PKP from January 2000 to December 2008 and had a minimum follow-up of 6 months were reviewed. All corneas were obtained from eye banks in the US. Indications, complications, and outcomes of surgery were recorded. This study was approved by the institutional review board. Results: Eighty-five consecutive eyes were included in this study. There were 52 (61.2% males and 33 (38.8% females. The median age was 35.0 years (range 3–85 years, and the median follow-up period was 24 months (range 6–108 months. The indications for PKP were keratoconus, bullous keratopathy, corneal scars, corneal dystrophy, and corneal regraft. The overall graft survival time was 88.9 months ± 4.9 months (mean ± standard error of mean, 95% confidence interval [CI] 79.4 months -98.4 months while the 3-year and 5-year cumulative survival rates were 90.7% and 84.3%, respectively. Surgical indication (P = 0.038, immune rejection (P < 0.001, preoperative corneal vascularization (P = 0.022, and perioperative high intraocular pressure (P = 0.032 were associated significantly with corneal graft failure in univariate analysis. Multivariate analysis reduced these significant associations to rejection (P < 0.001 and vascularization (P = 0.009. Relative risk for failure in rejected cornea was 16.22 (95% CI 4.99–52.69 and

  6. European Society for Swallowing Disorders – European Union Geriatric Medicine Society white paper: oropharyngeal dysphagia as a geriatric syndrome

    Directory of Open Access Journals (Sweden)

    Baijens LW

    2016-10-01

    Full Text Available Laura WJ Baijens,1 Pere Clavé,2,3 Patrick Cras,4 Olle Ekberg,5 Alexandre Forster,6 Gerald F Kolb,7 Jean-Claude Leners,8 Stefano Masiero,9 Jesús Mateos-Nozal,10 Omar Ortega,2,3 David G Smithard,11 Renée Speyer,12 Margaret Walshe13 1Department of Otorhinolaryngology – Head and Neck Surgery, Maastricht University Medical Center, Maastricht, the Netherlands; 2Gastrointestinal Physiology Laboratory, Department of Surgery, Hospital of Mataró, Autonomous University of Barcelona, Mataró, 3CIBERehd, Instituto de Salud Carlos III, Barcelona, Spain; 4Department of Neurology, Antwerp University Hospital, University of Antwerp, Born Bunge Institute, Edegem, Belgium; 5Department of Translational Medicine, Division of Medical Radiology, Skåne University Hospital, Malmö, Sweden; 6Clinique Bois-Bougy, Nyon, Switzerland; 7Department of Geriatrics and Physical Medicine, Bonifatius Hospital, Lingen, Germany; 8Long Term Care and Hospice, Ettelbruck, Luxembourg; 9Rehabilitation Unit, Department of Neuroscience, University of Padua, Padova, Italy; 10Department of Geriatric Medicine, Hospital Ramón y Cajal, Madrid, Spain; 11Clinical Gerontology, Princess Royal University Hospital, King’s College Hospital Foundation Trust, London, UK; 12College of Healthcare Sciences, James Cook University, Townsville, QLD, Australia; 13Department of Clinical Speech and Language Studies, Trinity College Dublin, Dublin, Ireland Abstract: This position document has been developed by the Dysphagia Working Group, a committee of members from the European Society for Swallowing Disorders and the European Union Geriatric Medicine Society, and invited experts. It consists of 12 sections that cover all aspects of clinical management of oropharyngeal dysphagia (OD related to geriatric medicine and discusses prevalence, quality of life, and legal and ethical issues, as well as health economics and social burden. OD constitutes impaired or uncomfortable transit of food or liquids

  7. Relationship between thermotectonic evolution of Serra do Mar mountain range and Santos Basin, SP, Brazil, accessed through fission track analysis in apatite

    International Nuclear Information System (INIS)

    Hadler, J.C; Tello, S.C.A; Iunes, P.J.; Guedes, S; Hackspacher, P; Paulo, S.R; Ribeiro, L.F.B

    2001-01-01

    the laboratory use. Through these models, these times are extrapolated to geological ones. The most employed model was proposed by Laslett et al. (1987). It is based on the best fit of the annealing data set by Green et al. (1986). By this model, a track length distribution can be obtained from both the thermal history and age of a sample. However, what one can obtain through the FTM is the track length distribution and what one wants is the thermal history. The employment of the model in this 'inverse' way was proposed by Lutz and Omar (1991) and is widely accepted since then. In this work, the 'inverse model' was utilized to determine the thermal history of a group of samples collected in Serra do Mar Mountain Range (SMMR). As these samples were collected in the same tectonic unit, a common thermal history is a plausible expectation. To show the consistence of this analysis, the relationship between the obtained thermal history and stratigraphic data of Santos Basin is presented (au)

  8. A video demonstration of preserved piloting by scent tracking but impaired dead reckoning after fimbria-fornix lesions in the rat.

    Science.gov (United States)

    Whishaw, Ian Q; Gorny, Boguslaw P

    2009-04-24

    Piloting and dead reckoning navigation strategies use very different cue constellations and computational processes (Darwin, 1873; Barlow, 1964; O'Keefe and Nadel, 1978; Mittelstaedt and Mittelstaedt, 1980; Landeau et al., 1984; Etienne, 1987; Gallistel, 1990; Maurer and Se guinot, 1995). Piloting requires the use of the relationships between relatively stable external (visual, olfactory, auditory) cues, whereas dead reckoning requires the integration of cues generated by self-movement. Animals obtain self-movement information from vestibular receptors, and possibly muscle and joint receptors, and efference copy of commands that generate movement. An animal may also use the flows of visual, auditory, and olfactory stimuli caused by its movements. Using a piloting strategy an animal can use geometrical calculations to determine directions and distances to places in its environment, whereas using an dead reckoning strategy it can integrate cues generated by its previous movements to return to a just left location. Dead reckoning is colloquially called "sense of direction" and "sense of distance." Although there is considerable evidence that the hippocampus is involved in piloting (O'Keefe and Nadel, 1978; O'Keefe and Speakman, 1987), there is also evidence from behavioral (Whishaw et al., 1997; Whishaw and Maaswinkel, 1998; Maaswinkel and Whishaw, 1999), modeling (Samsonovich and McNaughton, 1997), and electrophysiological (O'Mare et al., 1994; Sharp et al., 1995; Taube and Burton, 1995; Blair and Sharp, 1996; McNaughton et al., 1996; Wiener, 1996; Golob and Taube, 1997) studies that the hippocampal formation is involved in dead reckoning. The relative contribution of the hippocampus to the two forms of navigation is still uncertain, however. Ordinarily, it is difficult to be certain that an animal is using a piloting versus a dead reckoning strategy because animals are very flexible in their use of strategies and cues (Etienne et al., 1996; Dudchenko et al., 1997

  9. Regarding optical coherence tomography grading of ischemia in central retinal venous occlusion

    Directory of Open Access Journals (Sweden)

    Tripathy K

    2017-02-01

    Full Text Available Koushik TripathyDepartment of Vitreoretina and Uvea, ICARE Eye Hospital & Postgraduate Institute, Noida, Uttar Pradesh, IndiaThe author read with interest the article by Browning et al.1 The author humbly wants to discuss a few facts.1. The article1 discusses grading of retinal ischemia based on optical coherence tomography features in central retinal venous occlusion. As coexisting central retinal arterial occlusion or cilioretinal arterial occlusion may also cause inner retinal hyper-reflectivity, exclusion of such cases is an important consideration before implicating central retinal venous occlusion for the ischemia. Extensive intraretinal hemorrhages are other important hindrances to the evaluation of the perfusion status of the retina using both fluorescein angiogram and optical coherence tomography.2. It would be interesting to know the gonioscopic findings, especially neovascularization of the anterior chamber angle if it was performed at presentation and during the follow-ups.3. The manuscript documented that the incidence of anterior segment neovascularization at 1 year was 8.9% in severe ischemia group.1 The incidence of anterior segment neovascularization in perfused groups was higher (15.4% and 17.6% for mild and moderate ischemia, respectively. Although the sample size was low, such findings are contrary to the literature2 and require further discussion. Authors' replyDavid J Browning, Omar S Punjabi, Chong LeeDepartment of Ophthalmology, Charlotte Eye, Ear, Nose and Throat Associates, P.A., Charlotte, NC, USA We thank Dr Tripathy for his interest in our article and would respond to his above-mentioned points.1. We agree that excluding eyes with cilioretinal artery and central retinal artery occlusions is necessary to be able to attribute inner retinal reflectivity changes to central retinal vein occlusion. Cilioretinal artery occlusion is associated with a band of ischemic retinal whitening and central retinal artery occlusion

  10. List of participants of the VI School on Cosmic Rays and Astrophysics 17-25 November 2015, Chiapas, Mexico

    International Nuclear Information System (INIS)

    2017-01-01

    Lecturers: 1.- Oscar Saavedra San Martín Università di Torino and Istituto Nazionale di FisicaNucleare (INFN, Italy) 2.- Mario Rodríguez Cahuantzi Benemérita Universidad Autónoma de Puebla (BUAP) 3.- Alberto Carramiñana Instituto Nacional de Astrofísica, Óptica y Electrónica (INAOE, Mexico) 4.- Marco Casolino Rikagaku Kenkyusho, Research Institute (RIKEN, Japan) and INFN (Italy) 5.- Paolo Desiati Wisconsin IceCube Particle Astrophysics Center (WIPAC), Department of Astronomy (Madison, USA) 6.- Paolo Lipari Sezione Roma I dell’ INFN, Universita’ degli Studi “La Sapienza” c/o Istituto di Fisica (Italy) 7.- Juan Carlos Arteaga Velázquez Instituto de Física y Matemáticas of Universidad Michoacana de San Nicolás de Hidalgo (IFM-UMSNH, Mexico) 8.- Karen Salomé Caballero Mora Facultad de Ciencias en Física y Matemáticas, Universidad Autónoma de Chiapas (FCFM-UNACH, Mexico) 9.- Pat Harding Los Alamos National Laboratory (LANL, USA) 10.- Omar Miranda Romagnoli Departamento de Física, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV-Mexico) 11.- Pierluigi Belli INFN Roma Tor Vergata (Italy) 12.- Giuseppe Di Sciascio Departament of Physics (INFN, Italy) 13.- César Álvarez Ochoa FCFM-UNACH, Mexico 14.- Luis Villaseñor IFM-UMSNH, Mexico 15.- Jorge Romo FCFM-UNACH, Mexico 16.- Lukas Nellen Instituto de Ciencias Nucleares, Universidad Nacional Autónoma de México (ICN-UNAM, Mexico) Students: 1.- Ibrahim Torres, INAOE, Mexico 2.-Andrea Correa, Escuela Politécnica Nacional, Ecuador 3.- Humberto Martínez Huerta, CINVESTAV, Mexico 4.- Iván Antonio Cárdenas Muñoz, Universidad de Sonora, Mexico 5.- Juan Antonio Salazar Contreras, Escuela de Ciencias Físicas y Matemáticas, Universidad de San Carlos de Guatemala, USAC, Guatemala 6.- Pravda Linda Flor Cabrera Vogel, USAC, Guatemala 7.- Luis Guillermo García Ordóñez, USAC, Guatemala 8.- Marco Antonio Morales Ovalle, USAC, Guatemala 9.- Joshua Raphael L

  11. Prosecuting the Leaders: Promises, Politics and Practicalities

    Directory of Open Access Journals (Sweden)

    Robert Cryer

    2009-02-01

    Yugoslavia (ICTY by dying before the end of his trial, Saddam Hussein was prosecuted and sentenced to death before the Iraqi High Tribunal, and Omar al-Bashir has recently been the subject of a request for an arrest warrant from the Prosecutor of the International Criminal Court. Surely international criminal law reaches its iconographic apogee with the prosecution of such leaders,  brought down to size by the majesty of the law (if not the grandeur of the often aseptic courtrooms?

  12. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2002-04-01

    University Press, xiv + 299 pp. [Yale Southeast Asia studies monograph 48.] 1999 -Bernice de Jong Boers, Peter Just, Dou Donggo justice; Conflict and morality in an Indonesian society. Lanham, Maryland: Rowman and Littlefield, 2001, xi + 263 pp. -Nico J.G. Kaptein, Howard M. Federspiel, Islam and ideology in the emerging Indonesian state; The Persatuan Islam (PERSIS, 1923 to 1957. Leiden: Brill, 2001, xii + 365 pp. -Gerrit Knaap, Els M. Jacobs, Koopman in Azië; De handel van de Verenigde Oost-Indische Compagnie tijdens de 18de eeuw. Zutphen: Walburg Pers, 2000, 304 pp. -Toon van Meijl, Bruce M. Knauft, From primitive to postcolonial in Melanesia and anthropology. Ann Arbor: University of Michigan Press, 1999, x + 320 pp. -Jennifer Nourse, Juliette Koning ,Women and households in Indonesia; Cultural notions and social practices. Richmond, Surrey: Curzon, 2000, xiii + 354 pp., Marleen Nolten, Janet Rodenburg (eds -Sandra Pannell, Clayton Fredericksen ,Altered states; Material culture transformations in the Arafura region. Darwin: Northern Territory University Press, 2001, xiv + 160 pp., Ian Walters (eds -Anne Sofie Roald, Alijah Gordon, The propagation of Islam in the Indonesian-Malay archipelago. Kuala Lumpur: Malaysian sociological research institute, 2001, xxv + 472 pp. -M.J.C. Schouten, Mary Taylor Huber ,Gendered missions; Women and men in missionary discourse and practice. Ann Arbor: The University of Michigan Press, 1999, x + 252 pp., Nancy C. Lutkehaus (eds -Karel Steenbrink, Nakamura Mitsuo ,Islam and civil society in Southeast Asia. Singapore: Institute of Southeast Asian studies, 2001, 211 pp., Sharon Siddique, Omar Farouk Bajunid (eds -Heather Sutherland, Robert Cribb, Historical atlas of Indonesia, Richmond, Surrey: Curzon, 2000, x + 256 pp. -Sikko Visscher, Lee Kam Hing ,The Chinese in Malaysia. Kuala Lumpur: Oxford University Press, 2000, xxix + 418 pp., Tan Chee-Beng (eds -Edwin Wieringa, Jane Drakard, A kingdom of words; Language and power in Sumatra. Kuala

  13. Integrated Care in Prostate Cancer (ICARE-P): Nonrandomized Controlled Feasibility Study of Online Holistic Needs Assessment, Linking the Patient and the Health Care Team.

    Science.gov (United States)

    Nanton, Veronica; Appleton, Rebecca; Dale, Jeremy; Roscoe, Julia; Hamborg, Thomas; Ahmedzai, Sam H; Arvanitis, Theodoros N; Badger, Douglas; James, Nicholas; Mendelsohn, Richard; Khan, Omar; Parashar, Deepak; Patel, Prashant

    2017-07-28

    clinical teams. Recruitment to the second phase of the study, the feasibility trial, commenced March 2017. To our knowledge, this study is the first in the United Kingdom to trial an online holistic needs assessment for men with prostate cancer, with data shared between patients and primary and secondary care providers. This study addresses recommendations in recent policy documents promoting the importance of data sharing and enhanced communication between care providers as a basis for care integration. We anticipate that this model of care will ultimately provide important benefits for both patients and the National Health Service. International Standard Randomized Controlled Trial Number (ISRCTN): 31380482; http://www.isrctn.com/ISRCTN31380482 (Archived by WebCite at http://www.webcitation.org/6s8I42u5N). ©Veronica Nanton, Rebecca Appleton, Jeremy Dale, Julia Roscoe, Thomas Hamborg, Sam H Ahmedzai, Theodoros N Arvanitis, Douglas Badger, Nicholas James, Richard Mendelsohn, Omar Khan, Deepak Parashar, Prashant Patel. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 28.07.2017.

  14. Editorial

    Directory of Open Access Journals (Sweden)

    AHM Zahirul Alam

    2018-06-01

    Full Text Available     IIUM ENGINEERING JOURNAL     CHIEF EDITOR Ahmad Faris Ismail, IIUM, Malaysia TECHNICAL EDITOR Erry Yulian Triblas Adesta, IIUM, Malaysia EXECUTIVE EDITOR AHM Zahirul Alam, IIUM, Malaysia ASSOCIATE EDITOR Anis Nurashikin Nordin, IIUM, Malaysia LANGUAGE EDITOR Lynn Mason, Malaysia COPY EDITOR Hamzah Mohd. Salleh, IIUM, Malaysia   EDITORIAL BOARD MEMBERS Abdullah Al-Mamun, IIUM, Malaysia Abdumalik Rakhimov, IIUM, Malaysia Amir Akramin Shafie, IIUM, Malaysia Erwin Sulaeman, IIUM, Malaysia Hanafy Omar, Saudi Arabia Hazleen Anuar, IIUM, Malaysia Konstantin Khanin, University of Toronto, Canada Ma'an Al-Khatib, IIUM, Malaysia Md Zahangir Alam, IIUM, Malaysia Meftah Hrairi, IIUM, Malaysia Mohamed B. Trabia, United States Mohammad S. Alam, Texas A&M University-Kingsville, United States Muataz Hazza Faizi Al Hazza, IIUM, Malaysia Mustafizur Rahman, National University Singapore, Singapore Nor Farahidah Binti Za'bah, IIUM, Malaysia Ossama Abdulkhalik, Michigan Technological University, United States Rosminazuin AB. Rahim, IIUM, Malaysia Waqar Asrar, IIUM, Malaysia     AIMS & SCOPE OF IIUMENGINEERING JOURNAL The IIUM Engineering Journal, published biannually, is a carefully refereed international publication of International Islamic University Malaysia (IIUM. Contributions of high technical merit within the span of engineering disciplines; covering the main areas of engineering: Electrical and Computer Engineering; Mechanical and Manufacturing Engineering; Automation and Mechatronics Engineering; Material and Chemical Engineering; Environmental and Civil Engineering; Biotechnology and Bioengineering; Engineering Mathematics and Physics; and Computer Science and Information Technology are considered for publication in this journal. Contributions from other areas of Engineering and Applied Science are also welcomed. The IIUM Engineering Journal publishes contributions under Regular papers, Invited review papers, Short communications, Technical

  15. The 15th Biannual National Congress of the South African Society of Psychiatrists, 10-14 August 2008, Fancourt, George, W Cape

    Directory of Open Access Journals (Sweden)

    Eugene Allers

    2008-08-01

    Full Text Available 1. How can we maintain a sustainable private practice in the current political and economic climate? Eugene Allers 2. SASOP Clinical guidelines, protocols and algorithms: Development of treatment guidelines for bipolar mood disorder and major depression  Eugene Allers, Margaret Nair, Gerhard Grobler 3. The revolving door phenomenon in psychiatry: Comparing low-frequency and high-frequency users of psychiatric inpatient services in a developing country U A Botha, P Oosthuien, L Koen, J A Joska, J Parker, N Horn 4. Neurophysiology of emotion and senses - The interface between psyche and soma Eugene Allers 5. Suicide prevention: From and beyond the psychiatrist's hands O Alonso Betanourt, M Morales Herrera 6. Treatment of first-episod psychosis: Efficacy and toleabilty of a long-acting typical antipsychotic B Chiliza, R Schoeman, R Emsey, P Oosthuizen, L KOen, D Niehaus, S Hawkridge 7. Treatment of attention deficit hyperactivity disorder in the young child Helen Clark 8. Holistic/ Alternative treatment in psychiatry: The value of indigenous knowledge systems in cllaboration with moral, ethical and religious approaches in the military services J Dill 9. Treating Schizophrenia: Have we got it wrong? Robin Emsley 10.Terminal questions in the elderly Mike Ewart Smith 11. Mental Health Policy development and implementation in Ghana, South Africa, Uganda and Zambia Alan J Flisher, Crick Lund, Michelle Frank, Arvin Bhana, Victor Doku, Natalie Drew, Fred N Kigozi, Martin Knapp, Mayeh Omar, Inge Petersen, Andrew Green andthe MHaPP Research Programme Consortium 12. What indicators should be used to monitor progress in scaling uo services for people with mental disorders? Lancet Global Mental Health Group (Alan J Flisher, Dan Chisholm, Crick Lund, Vikram Patel, Shokhar Saxena, Graham Thornicroft, Mark Tomlinson 13. Does unipolar mania merit research in South Africa? A look at the literature Christoffel Grobler 14. Revisiting the Cartesian duality of mind

  16. The Emphasizing Metonymy and Its Relation Whit Ambiguity of Text

    Directory of Open Access Journals (Sweden)

    Amir Saleh Masoomi

    2016-05-01

    holy scripture like the Quran? What is the position of this combined tool in Arabic language?   Such questions prompted us to study the validity of this linguistic phenomenon by using of descriptive-analytical method and explain its effect on perception of reader. On the basis of data of this article, the emphasizing metonymy in contrary to its illogical appearance could be an acceptable phenomenon in the tradition of Arabic language.   References   1. Holy Quran , Fuladvand, Mohammad Mahdi & Payande, Abul Qasem (trans..   2. Abouhayan, Mohamed ibn Youssef (1998. Irteshaf az-Zarab min Lisan al-Arab. Osman Mohammed Rajab and Ramadan Abdaltwab (Emend.. Cairo: Khanji library.   3. ------------------------------------------ (2001.Tafsir al- Bahr al-Mohit. Adel Ahmed Abdol-Mowjood and Ali Mohamed Moawad (Emend.. Beirut: House of scientific books.   4. Astrabadi, Radhi ad-Din Muhammad ibn al-Hasan (1996. Sharh ar-Razi al-Kafyah. Yusuf Hassan Omar (Emend.. Benghazi: University Publications of Garyounes.   5. Azhari, Muhammad bin Ahmad (2001. Tahzib al- loghah. Mohamed Awad terrifying (Emend.. Beirut: House of Revival of Islamic Heritage.   6. Farazdak, Bin Hammam Ghalib (1987. Diwan of Farazdaq. Ali Faour (Emend.. Beirut: House of scientific books.   7. Ibn Abi al-Esba, Abdul Azim ibn al-vahid (1963. Tahrir al-Tahbir fi sana'at al-sher va al-nathr va bayan ejaz alquran. Hafni Mohammad Sharaf (Emend.. Cairo: grope of Revival of Islamic Heritage .   8. Ibn Ashur, Muhammad Tahir (1997. Al-Tahrir va al- Tahbir. Tunisia: Dar Sahnoun for publication and distribution.   9. Ibn Jenni, Abul Fath Othman ibn Jenni (1952. Al-Khasa'es. Mohammad Ali al-Najar (Emend.. Beirut: Book World.   10. Jmaha, Muhammad ibn Salaam (n.d.. Tabaghat al-Fohul al-sho'ara. Mahmoud Mohamed Shaker (Emend.. Jiddah: Dar al-madani.   11. Khatib Qazwini, Muhammad ibn Abd or-Rahman (n.d.. Al-Talkhis fi Olum al-Balaghah. Abdulrahman Albrkoqa (explain. Egypt: Arab Thought House

  17. Correlation of 18F-fluoroethyl tyrosine positron-emission tomography uptake values and histomorphological findings by stereotactic serial biopsy in newly diagnosed brain tumors using a refined software tool

    Directory of Open Access Journals (Sweden)

    Lopez WO

    2015-12-01

    Full Text Available William Omar Contreras Lopez,1,2 Joacir Graciolli Cordeiro,1 Ulrich Albicker,3 Soroush Doostkam,4 Guido Nikkhah,1,5 Robert D Kirch,6 Michael Trippel,1 Thomas Reithmeier1,7 1Department of Stereotactic and Functional Neurosurgery, University Medical Center Freiburg, Freiburg im Breisgau, Germany; 2Division of Functional Neurosurgery, Department of Neurology, Hospital das Clinicas, University of São Paulo Medical School, São Paulo, Brazil; 3Inomed, Emmendingen, 4Department of Neuropathology, University Medical Center Freiburg, Freiburg im Breisgau, 5Department of Neurosurgery, University Clinic Erlangen, Erlangen, 6Neuroelectronic Systems, Department of Neurosurgery, University Medical Center Freiburg, Freiburg im Breisgau, 7Department of Neurosurgery, Schwabing Academic Teaching Hospital of Technical University and Ludwig Maximilian University of Munich, Munich, Germany Background: Magnetic resonance imaging (MRI is the standard neuroimaging method to diagnose neoplastic brain lesions, as well as to perform stereotactic biopsy surgical planning. MRI has the advantage of providing structural anatomical details with high sensitivity, though histological specificity is limited. Although combining MRI with other imaging modalities, such as positron-emission tomography (PET, has proven to increment specificity, exact correlation between PET threshold uptake ratios (URs and histological diagnosis and grading has not yet been described.Objectives: The aim of this study was to correlate exactly the histopathological criteria of the biopsy site to its PET uptake value with high spatial resolution (mm3, and to analyze the diagnostic value of PET using the amino acid O-(2-[18F]fluoroethyl-L-tyrosine (18F-FET PET in patients with newly diagnosed brain lesions in comparison to histological findings obtained from stereotactic serial biopsy.Patients and methods: A total of 23 adult patients with newly diagnosed brain tumors on MRI were enrolled in this study

  18. Advances In Global Aerosol Modeling Applications Through Assimilation of Satellite-Based Lidar Measurements

    Science.gov (United States)

    Campbell, James; Hyer, Edward; Zhang, Jianglong; Reid, Jeffrey; Westphal, Douglas; Xian, Peng; Vaughan, Mark

    2010-05-01

    ]. Inversion retrievals of aerosol extinction are performed for one-degree latitudinal averages of CALIOP backscatter signal (thus matching the horizontal resolution of NAAPS) by constraining total column transmission using the model estimate of AOD at the corresponding wavelength. As such, this system serves as a post-processing module predicated on newly-operational NAAPS aerosol analysis fields that feature 2D-VAR assimilation of NASA Moderate Resolution Infrared Spectroradiometer (MODIS) AOD observations [Zhang and Reid, 2006; Zhang et al., 2008]. We describe the influence of 3D-VAR assimilation on NAAPS analyses and forecasts by considering the physical evolution of Saharan dust plumes during their advection across the tropical Atlantic basin. Steps taken towards characterizing spatial covariance parameters that broaden the horizontal influence of information obtained along the limited lidar orbital swath are discussed. This latter context is critical when comparing the efficacy and impact of 3D-VAR assimilation with that of 2D-VAR procedures, which benefit from passive observations with a relatively wide field-of-view and, therefore, greater/more routine global coverage. With multiple satellite-lidar projects either pending launch or in design stages, including the dual ESA missions (AEOLUS and EarthCARE), we describe the potential impact of future 3D-VAR assimilation activities; both for NAAPS forecast capabilities, and the anticipated growth in aerosol transport modeling efforts at federal and cooperative global agencies worldwide. 1 http://www.nrlmry.navy.mil/aerosol/ References Campbell, J. R., J. S. Reid, D. L. Westphal, J. Zhang, E. J. Hyer, and E. J. Welton, CALIOP aerosol subset processing for global aerosol transport model data assimilation, in press, J. Selected Topics Appl. Earth Obs. Rem. Sens., December 2009. Winker, D. M., M. A. Vaughan, A. Omar, Y. Hu, K. A. Powell, Z. Liu, W. H. Hunt, and S. A. Young, Overview of the CALIPSO mission and CALIOP data

  19. The distribution of seagrasses in Dominica, Lesser Antilles

    Directory of Open Access Journals (Sweden)

    S.C.C Steiner

    2010-10-01

    wrightii creció en las costad del norte y oeste, en profundidades de 1 a 14m en áreas de perturbaciones recientes o crónicas. Su morfología delicada y su baja cobertura béntica (<0.1% no constituyeron pastos. Halophila decipiens creció en los márgenes profundos, llanos y laterales de pastos dominados por S. filiforme, pero también en forma mono-específica entre 3 y 24m. Halophila stipulacea, una especie invasora, se encontró comúnmente a lo largo de 45km de la costa del oeste en profundidades entre 5 y 24m. Ambas especies de Halophila formaron pastos extensos en profudidades mayores al límite de este estudio y puden ser importantes en la recolonización de áreas llanas después de tormentas destructivas. H. decipiens y H. stipulacea ahora son las especies más comunes después de S. filiforme, a pesar de su ausencia en la costa del norte. T. testudinum, sólo creció en la costa del norte, encima de áreas arrecifales con un pormedio de cobertura béntica entre 2 y 76%, en aguas con 1m o menos de profundidad. Crecieron mono-específicamente en áreas de turbulencia máxima y mínima, pero entre S. filiforme en áreas de turbulencia moderada. Oleaje fuerte en la costa del oeste (octubre 16, asociado con el Huracán Omar, causó la erosión y el enterramiento variado de las márgenes llanas de pastos marinos, particularmente entre 2 y 10m de profundidad. Este evento demostró la dinámica en las márgenes llanas de pastos marinos de Dominica y el nivel de resistencia a perturbaciones de pastos individuales.

  20. Achieving a milestone: AMOR is now archived in Portico and indexed in CAS

    Directory of Open Access Journals (Sweden)

    R.N Sugitha Nadarajah

    2016-10-01

    Full Text Available The journal of Advances in Modern Oncology Research (AMOR is proud to announce its partnership with Portico, a leading digital preservation service provider, to ensure the long term accessibility of its published contents. In addition, it is now indexed by the gold standard of chemical information database Chemical Abstracts Services (CAS after publishing only six bimonthly issues, dating back to October 2015. AMOR’s Editor-in-Chief Dr. Omar Abdel-Rahman proudly shares: “Our vision is to be far more than just a journal, we want to be a platform that publishes high quality cancer research contents from all over the world. I think we are progressing, at an acceptable pace, in that direction."The Portico archive is a “centralized repository of tens of thousands of e-journals, e-books, and other electronic content, replicated to ensure security,” according to the registry organization. “Content comes into the archive under formal preservation agreements with publishers. Content providers submit source files to Portico, and we repackage these source files into an archival format and provide long-term archival management and format migration as needed. Our approach is driven by our commitment to meeting clear preservation goals,” it states. AMOR’s Managing Editor Dr. TS Jong, when asked to comment about the impact of this development, adds: “AMOR is committed towards meeting the highest international publication standards and as such, has a clear archiving and indexing roadmap to sustain our growth. The journal acknowledges the importance of ensuring the continuous accessibility of our published articles in multiple repositories. Therefore, we are delighted with the recent partnership between AMOR and Portico, a well-known third-party repository service provider, to safeguard the long-term availability of our contents.”Archiving AMOR’s articles within Portico ensures that the materials published are always available for access. In

  1. Proceedings of the 2015 WAO Symposium on Food Allergy and the Microbiome

    Directory of Open Access Journals (Sweden)

    Raúl Lázaro Castro Almarales

    2016-10-01

    Full Text Available Table of contents A1 Characterization of the immunoallergic profile towards the proteins of the wheat flour in Cuban population Raúl Lázaro Castro Almarales, Mary Carmen Reyes Zamora, Beatriz Tamargo, Damaris Torralba Averoff, Raysa Cruz, Yunia Oliva Diaz, Mirta Alvarez Castello, Alexander Ciria, Alexis Labrada, Maytee Mateo A2 Are peanuts causing food allergy in Cuba? Maytee Mateo, Damaris Torralba Averoff, Raysa Cruz, Yunia Oliva Diaz, Mirta Alvarez Castello, Alexander Ciria, Mary Carmen Reyes Zamora, Beatriz Tamargo, Alexis Labrada A3 Prick test and immunoallergic profile to soy allergens in Cuban population Omar Herrera, Maytee Mateo, Raysa Cruz, Mirta Alvarez Castello, Alexander Ciria, Raúl Lázaro Castro Almarales, Mary Carmen Reyes Zamora, Alexis Labrada A4 Skin sensitization and immunoallergic profile to hen's egg in Cuban population José Severino Rodríguez Canosa, Raysa Cruz, Maytee Mateo, Mirta Alvarez Castello, Alexander Ciria, Raúl Lázaro Castro Almarales, Mary Carmen Reyes Zamora, Alexis Labrada A5 Sensitization to three domestic mites in patients with adverse food events to shellfish Mirta Alvarez Castello, Raúl Lázaro Castro Almarales, Alexis Labrada, Biocen A6 Diagnostic efficacy by skin prick test with allergenic extracts of legumes in Cuban patients Yamilet Ibizate Novales, Ilonka Estruch Fajardo, Alexis Labrada, Maytee Mateo, Armando Ginard A7 Baked egg goods without wheat flour carry an increased risk of reaction Bruce Lanser, Anna Faino, Erwin Gelfand, Pia Hauk A8 Prevalence, incidence and associated risk factors of adverse reaction to food in Cuban infants - a population-based prospective study Silvia Venero Fernández, Julia Urbina, Mirta Alvarez Castello, Raúl Lázaro Castro Almarales, Ramón Suárez Medina, Hermes Fundora Hernández, John Britton, Andrew William Fogarty A9 Microbiome in ice machines and assessing the plasma nanotechnology in breaking the biofilm and improving air quality Nabarun Ghosh, Clinton

  2. PREFACE: 17th International Conference on the Physics of Highly Charged Ions

    Science.gov (United States)

    2015-01-01

    persons had the opportunity to enjoy a comfortable and friendly ambiance as well as the beautiful landscapes of the region including big lakes and high mountains. During the conference vivid and interesting scientific discussions were maintained by the participants in a relaxed environment. The Local Organizing Committee would like to recognize the generous contributions made by various institutions: International Pure and Applied Physics (IUPAP), Comisión Nacional de Energía Atómica (CNEA), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Investigación Aplicada S. E. (INVAP), Patagonia Norte Division of CONICET, Instituto Balseiro and NEC Corporation. The Local Chairs would like to express their gratitude to all the other members of the Local Organizing Committee who collaborated with a great effort and in countless ways to the success of the conference. In particular, we thank Omar Fojón for the outstanding collaboration received, and Juan Manuel Monti, who worked hard for the production of the Book of Abstracts and other related activities. We also would like to thank Renata Della Picca, Juana Gervasoni and Silvina Seguí, for their generous work in printing the book of abstracts, bags, banners, etc. and for their continuous help at the Registration Desk. We extend our gratitude to the younger members of the Local Organizing Committee, Marcos Feole, Francisco Navarrete and Juan Martín Randazzo for their help with the poster logistics; and to Luis Rodríguez for ensuring that all the presentations were ready and on schedule. We thank María Silvia Gravielle, our colleague and liaison in Buenos Aires, for helping delegates to get their visas on time; Sebastián Otranto and Jocelyn Hanssen, for their early work collecting and sorting the talk's proposals and Carlos Stia, for helping with the revision of the style of the manuscripts. We also thank M. Galassi, P Focke and D. Fregenal. We recognize Sergio Suárez, for getting funding from private

  3. Editorial

    Directory of Open Access Journals (Sweden)

    Clarice Helena de Miranda Coimbra

    2015-01-01

    jurídica: algumas questões relacionadas à sua adoção”. O estudo da autora procura demonstrar algumas questões relacionadas com a possibilidade de incriminar o Estado. O nono artigo intitula-se “Mal de archivo, fugas y huecos”, de autoria do nosso editor associado Eber Omar Betanzos Torres, o qual apresenta de forma sucinta e esclarecedora baseando-se nos pensamentos de Jacques Derrida, Sigmund Freud e outros. Héctor Antuñano Gonzalez intitula seu artigo como “Pandillas transnacionales: um enfoque de seguridade nacional en México”, procurando corroborar se os processos de exclusão, pobreza e marginalização podem gerar uma presença maior em quadrilhas transnacionais, bem como demonstrar se a segurança nacional é violada por afetar as condições de governabilidade do Estado. O décimo primeiro artigo intitulado “Órganos y esquemas de la integración americana” é de autoria de Juan Pablo Pampillo Baliño, especialista no tema, apresenta balanço e perspectiva das principais propostas, mecanismos e projetos para a integração americana a partir da segunda metade do século XX. Por fim, apresentamos o décimo segundo artigo de autoria de Isabel Husid e de Leonardo Husid, intitulado “Business development, foreign direct investment and international trade: A policy and economic comparative analysis for canadathe future Law and economics perspective”, que tem por finalidade alcançar uma visão geral sobre investimento direto estrangeiro e comércio internacional no Canadá, sendo de suma importância para companhias e governos planejarem estratégias para investir e comercializar com o Canadá. Agradecemos aos autores que encaminharam seus artigos, que contribuíram com a matéria prima, acreditando na seriedade do projeto, e, ao mesmo tempo, convidamos novos pesquisadores a fazerem uso desse instrumento para divulgarem os resultados de suas investigações. Finalmente, desejamos a todos uma boa leitura! Clarice Helena de Miranda Coimbra

  4. Different Types of Fantastic Etiology in Hafez Poetry

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    Ghodrat Ghasemipour

    2016-05-01

    : Setare. Attar Nishabori, Farid od-Din (2000. Mohammad Reza Shafie Kadkani ( emend ., 5rd ed. Tehran: Sokan. Chalisova, Natalia (2004. Encyclopedia of Iranica. Last Updated: December 15. Farshidvard, Khosrow (1975. Conjugating of simile with another factors in Hafez poetry. Gowhar, No 18, 535-541. Ferdowsi, Abolghasem (2001. Shahname (Moscow Press. Saeed Hamidiyan (emend. 2nd Vol. 5rd ed. Tehran: Ghatreh. Forster, Edward Morgan (1974. Aspects of the Novel. Harmondswort: Penguin. Gharib Hoseini, Zahra and Mohammad Sadegh Basiri (2009. Techniques of usages of fantastic etiology in Anvari' Ghasayed. Kavoshname, 9th year, No 16, 65-97. Hafez, Khajeh Shams od-Din (1984. Hafez Divan. Parviz Natel Khanlari (emend.. 2rd ed. Tehran: Kharazmi. Heravi, Hoseinali (1977. Commentary of Hafez' Gazals. 4rd ed. Tehran: Simorgh. Homaei, Jalalodin (1989. Techniques of Rhetoric and Literary devices. 5rd ed. Tehran: Homa. Hoseini Nishabori, Ataola ibn Mahmoud (2006. Badaye alsanaye. Rahim Mosalmanian Ghobadiyani, Tehran: Institution of Mahmoud Afshar endowment s. Jacobson, Roman (2013. Dominant, in Mohammad Reza Shafi’ee Kadkani (trans. Resurrect of Words. Tehran: Sokan. Khabazha, Reza (2013 The Function of fantastic etiology in the structure of themes digression to eulogy. Monthly Book of Literature. No 73, 43-48. Mikics, David, (2007, A New Handbook of Literary Terms, Yale University Press, New Haven & London. Mohamadi Asiyabadi, Ali (2007. Projection and characterization in Hafez poetry. University of Tarbiyat Moalem, No 52 &53, p 111-134. Motahari, Morteza (1991. Lessons of Shafa Theology. Tehran: Hekmat. Radowyani, Mohammad ibn Omar (2002. Tarjoman e Balaghat. Ahmad Atash ( emend ., Tehran: Society of National Honor & Works. Shamisa, Sirus (2003. A New Glance on Rhetoric. 14rd ed. , Tehran: Ferdows. Shams Ololama Gorgani, Mohammad Hosein (1999. Ada ol-Badaye. Hosein Jafari ( emend ., Tabriz: Ahrar. Shams Ololama Gorgani, Mohammad Hosein (1999. Spring Clusters in Rhetoric. Morteza

  5. Editorial 32

    Directory of Open Access Journals (Sweden)

    Nylza Offir García Vera

    2011-12-01

    ón educativa para personas con discapacidad desde una posición que vincula tales procesos a las condiciones de posibilidad para una vida digna y con justicia social.De otra parte, las investigaciones acerca de los procesosde inclusión de estudiantes sordos a una institución educativa ofrecen también un panorama diverso de las condiciones no sólo físicas y materiales sino también pedagógicas, didácticas, disciplinares y contextuales que requiere esta educación inclusiva. Así lo reconocen tanto Pablo Salazar, Rita Flórez y Clemencia Cuervo ?a partir de las estructuras y prácticas organizacionales escolares que nos presentan? como el grupo Conocimiento profesionaldel profesor de Ciencias, que analiza estas mismas condiciones de inclusión en la educación superior, de manera específica en la Licenciatura en Biología de la Universidad Pedagógica Nacional.Desde la línea de las mediaciones e incorporación de las TIC en educación, dos reflexiones interpelan los ámbitos pedagógico y político de la educación virtual en nuestro país: la dimensión pedagógica como una reflexiónpendiente –tesis de Claudia Rozo– y la pregunta por las políticas que subyacen a este tipo de educación, aunada a la esfera política del ser humano –planteamientocentral del artículo de Diana Sáenz–. Por su parte, Myriam Leguízamo y Omar López examinan la relación existente entre el logro académico obtenido, por estudiantes de secundaria, en la interacción con un ambiente hipermedia sobre operadores tecnológicos y la formulación de metas de aprendizaje auto-impuestas y metas de aprendizaje asignadas.Conforman también este número un avance de la investigaciónen torno a la didáctica de la imagen ofrecida por Rafael Barragán y Wilson Gómez y una investigación culminada acerca del éxito en la Enseñanza de las CienciasBasada en Indagación (ECBI, un modelo aplicado en el marco del Programa Pequeños Científicos en la ciudad de Ibagué; el grupo de investigaci

  6. From the Editor

    Directory of Open Access Journals (Sweden)

    Ugur Demiray

    2005-09-01

    leadership and managerial implications of recent developments for higher education. Reviewing unique characteristics and the fundamental changes shaping higher education, the paper examines the need for organizational transformation and the major managerial implications. When we click the nineth paper you will see the article which is written by Prof. Dele BRAIMOH, National University of Lesotho, SOUTH AFRICA and Dr. Rebecca LEKOKO, University of Botswana, South Africa. My dear authors indicate in their paper aim is to stimulate dialogue on the significance, scope of coverage and the processes of formulating a policy framework for maintaining academic excellence as opposed to mediocrity. We are, however, mindful of the fact that practices are diverse in the region, but regardless of this diversity, a regional policy framework is possible to regulate the planning, development and implementation of quality distance education Programmes across all levels of education, with particular focus on higher institutions of learning. The tenth article was sent to TOJDE by Dr. I. Ahmed M. J. SADIIG is from Malaysia, International Islamic University Gombak. Dr. I. Ahmed M. J. SADIIG emphasizes in his article that the traditional learning paradigm involving face-to-face interaction with students is shifting to highly data-intensive electronic learning with the advances in Information and Communication Technology. An important component of the e-learning process is the delivery of the learning contents to their intended audience over a network. A distributed learning system is dependent on the network for the efficient delivery of its contents to the user. Next article is again from Malaysia, which written by group of Hanafi ATAN, Zuraidah A. RAHMAN, Omar MAJID, Noraida A. GHANI and Rozhan M IDRUS. In their article, they discuss on “The Support System in Distance Education: Factors Affecting Achievements Among Women Learners”. It is very important subject for TOJDE’s publishing

  7. Selected Abstracts of the 1st Congress of joint European Neonatal Societies (jENS 2015; Budapest (Hungary; September 16-20, 2015; Session “Brain & Development”

    Directory of Open Access Journals (Sweden)

    Various Authors

    2015-09-01

    PERINATAL ASPHYXIA REVEALS LASTING BEHAVIORAL DEFICITS • A. Kerenyi, E. Sipos, P. Bakos, K. Demeter, P. Pottyondi, J. Haller, M. Szabo, K. Kaila, E. Mikics, A. Denes, A. FeketeABS 28. EFFECT OF EARLY NUTRITION ON PRETERM CEREBRAL MATURATION AND BRAIN INJURY REFLECTED BY MR-IMAGING AT TERM • L. Beauport, J. Schneider, P. Hagmann, M. Faouzi, C.J. Fischer Fumeaux, A.C. TruttmannABS 29. NEURITE OUTGROWTH IN RESPONSE TO CEREBROSPINAL FLUID DERIVED FROM NEC-SENSITIVE PRETERM PIGS • J. Sun, S. Pankratova, D.E.W. Chatterton, P.T. SangildABS 30. URINARY NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN (NGAL AFTER GLOBAL HYPOXIA-ISCHEMIA IN NEWBORN PIGLETS • H.T. Garberg, M.U. Huun, G. Dyrhaug, R. Solberg, O.D. SaugstadABS 31. CEREBRAL DEEP GREY MATTER ALKALOSIS IN BABIES WITH NEONATAL ENCEPHALOPATHY IS ASSOCIATED WITH AN INCREASED SEIZURE BURDEN • C. Uria-Avellanal, D. Price, M. Sokolska, S. Mitra, A. Bainbridge, X. Golay, N. RobertsonABS 32. THE PROGNOSTIC VALUE OF NIRS DURING THERAPEUTIC HYPOTHERMIA IN TERM ASPHYXIATED NEWBORNS • P. Costa, A. Graça, I. Sampaio, C. MonizABS 33. EEG DISCONTINUITY PREDICTS CEREBRAL TISSUE INJURY AND ADVERSE NEURODEVELOPMENT IN COOLED NEWBORNS • J. Dunne, D. Wertheim, P. Clarke, O. Kapellou, P. Chisholm, J. Boardman, D. ShahABS 34. A RANDOMIZED CONTROLLED TRIAL OF COOLING COMBINED WITH INHALED XENON FOR PERINATAL ASPHYXIAL ENCEPHALOPATHY WITH CEREBRAL MAGNETIC RESONANCE ENDPOINTS – THE TOBY-Xe TRIAL • D. Azzopardi, N. Robertson, A. Bainbridge, E. Cady, A. Deierl, G. Fagiolo, N. Franks, J. Griffiths, J. Hajnal, E. Juszczak, B. Kapetanakis, L. Linsell, M. Maze, O. Omar, B. Strohm, N. Tusor, A.D. EdwardsABS 35. MULTIORGAN DYSFUNCTION IN NEWBORNS WITH HYPOXIC-ISCHEMIC ENCEPHALOPATHY IN THE HYPOTERMIA ERA • M. Alsina, A. Martin-Ancel, P. Alamillo, M. Leon, A Garcia-AlixABS 36. HYPOXIC-ISCHAEMIC BRAIN INJURY: DELIVERY BEFORE INTRAPARTUM EVENTS • D. Odd, A. Heep, K. Luyt, T. DraycottABS 37. IS NEONATAL ESTABLISHED HEARING LOSS PERMANENT IN

  8. Theory of Transcendent unity of Religion

    Directory of Open Access Journals (Sweden)

    Hossein Ali Torkamany

    2015-09-01

    Shinakht, Vol.2. No.2, 213-245 • Akbariyan, Reza, Jalali, Alireza,2008, A ciritical consideration on ancient view of the Unity of reliegions, The new religious thought journal, No:12 • Bahrami, Mohammad, 2002,A Critique on “Quran and pluralism”, Quranic research journal, No:32, 124-151 • Bahrami, Mohammad, 2003,A Critique on “Quran and pluralism”, Quranic research journal, No:33, 149-169 • Bahrani, seyed Hashem, 1995, Al-borhan, Trhran, Besat institute • Fakhr-e-Razi, mohammad ibn omar, 1999, Mafatih ol-gheyb, Beirut, Dar ehya al-toras al-arabi • Fazlollah, seyed mohammad Hosein,1998, men wahye Al-qoran, Beirut, Dar ol-melak • Feyz Kashani, Mohsen,1994, Al-safi, Tehran, Al-Sadr • Ghadrdan Gharamaleki, MohammadHasan, (n.d, Quran And Pluraism, Tehran, Youth thought center • Ghadrdan Gharamaleki, MohammadHasan,2003, A Critique on “Quran and pluralism”, Quranic researchs journal, No:33, 138-157 • Gharaati, Mohsen,1994, Tafsir-e-Noor, Tehran, Cultural Center of the lessons from the Quran • Glyn, Richards, 2001, Towards atheology of religions, translated by Gandomi NasrAbadi, Reza, Meftah, AhmadReza, Qom, Religious Studies and researchs Center, • Hick, john, 1993, Philosophy of Reliegion, Tehran, Al-hoda • Ibn babeweih, Mohammad ibn Ali, 1997,Al-amali, Tehran, Ketabchi • Ibn-r-e-manzur, mohammad ibn mokarram, 1993, Lesan ol-Arab, Beirut, Dar e sadr • Peterson ,Michael, Hasker ,William , Reichenbach, Bruce & Basinger ,David , 2010, Reason and religious belief, Tehran, Tarhe now • Javadi Amoli, Abd-o-allah, 2010, Religious studies, Qom. Esra • Javadi Amoli, Abd-o-allah, 2011, Tasnim, Qom. Esra • Karami, Tayebe, Kadivar, Mohsen, 2004, Relationship human diversity with a multiplicity of religions And the idea of transcendent unity of religions in the eyes of traditionalists Journal of Religious Thought , No:12 • Majlesi, Mohammadbagher, 1982 , Behar ol-Anwar(Seas of Lights , Beirut, Dar ehya al-toras al-arabi • Makarem, Shirazi