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Sample records for olle hints dimitri

  1. Dimitri Mitropoulos: Lonesome passage to modern music

    Directory of Open Access Journals (Sweden)

    Belonis Yanis

    2008-01-01

    Full Text Available It is not widely known that Dimitri Mitropoulos first public appearances in Greece were as a composer. His early works (ca. 1912-1924, distinguished by the blend of elements of the late-romantic style with intensely impressionistic references, reflect the search for a personal, 'advanced' harmonic musical language. In his works written after 1924, Mitropoulos abandons tonality and adopts more modern idioms of composition (atonality and 12-tone method. He is the first Greek composer to follow the modern musical tendencies of Europe, when music by Manolis Kalomiris and the other composers of the Greek National School was dominant in Greece.

  2. 9288 kilomeetrit suveülikooli / Dimitri Mironov

    Index Scriptorium Estoniae

    Mironov, Dimitri

    2009-01-01

    Tallinna Ülikooli Katariina kolledži direktor Dimitri Mironov tutvustab Suveülikooli õppereisi Venemaale, mis oli pühendatud Tallinna Ülikooli rahvusvahelise suvekooli vanimale, 15-aastaseks saanud eesti keele ja kultuuri kursusele. Reisi käigus sõideti rongiga Moskvast läbi Siberi Vladivostokki

  3. Sacred Symbols in Dimitrie Gavrilean’s Paintings

    Directory of Open Access Journals (Sweden)

    Emilian Adrian Gavrilean

    2016-05-01

    Full Text Available This year, on the 12th of July, there are four years since the passing away of the painter Dimitrie Gavrilean who, ,”through the unique impresion of his originality, early became an emblem of the school of painting of Iasi.” Born in Voroneţ, in 1942, Dimitrie Gavrilean attended ”Nicolae Grigorescu” Academy of Arts of Bucharest, being an eminent disciple of the master Corneliu Baba. The work in the creation workshop was combined with the vocation of teacher at the Faculty of Visual Arts and Design within ”G. Enescu” University of Arts of Iaşi, being a rector of this institution in the period 2000-2004. In the contemporary plastic landscape, the artistic work of the painter Dimitrie Gavrilean (1942-2012 from Iaşi occupies a special place. It mirrors the utmost of the autochthonous rural imaginary, the Romanian fundamental myths, the ancestral myths as well as the recently Christianized ones. His vision is specific to the Romanian Christianity and the Byzantine iconography. The language of Gavrilean’s paintings is one of symbols, by excellence. As Emil Staco rightfully observed, the entire work of art of master Gavrilean is ”a work of art of the symbols, of the metaphors rooted in the spirituality of the Romanian village of Bukovina, in the frescoes of Voroneţ and Humor Monasteries.” On the one hand, the painter did not content himself with illustrating only the ancestral mythical world by means of symbols with universal valences, but he got actively involved in the Christian valorization of mythical symbols. On the other hand, by integrating sacred symbols (the dove, the cock, winged characters, the wise old man, the architecture-church, the sun, Voroneţ blue of the Christian iconography of Byzantine tradition in paintings not necessarily religious, Dimitrie Gavrilean pushed his work of art to the border between sacred and profane, proving an extraordinary capacity of spiritualizing matter as well as of materializing the

  4. DIMITRI 1.0: Beschrijving en toepassing van een dynamisch input-output model

    NARCIS (Netherlands)

    Wilting HC; Blom WF; Thomas R; Idenburg AM; LAE

    2001-01-01

    DIMITRI, the Dynamic Input-Output Model to study the Impacts of Technology Related Innovations, was developed in the framework of the RIVM Environment and Economy project to answer questions about interrelationships between economy, technology and the environment. DIMITRI, a meso-economic model,

  5. “Through the Letter Sent with my Envoys to Kiev” St. Dimitry`s of Rostov Contacts with Kiev and Chernigov in 1701–1709

    Directory of Open Access Journals (Sweden)

    Krylov Aleksei

    2016-10-01

    Full Text Available The article examines st. Dimitry’s of Rostov contacts with Kiev and Chernigov in 1701–1709. Dimitry’s correspondence is vast, but addressees of the most of the known letters are Dmitry’s Moscow friend and Great Russian hierarchs. Problem of st. Dimitry’s contacts with his Little Russian acquaintances still remain obscure. This article deals with the information of st. Dimitry of Rostov correspondence with addressees in Kiev and Chernigov and the circumstances of Dimitry’s visit to Chernigov in 1704. In time of his episcopal service st. Dimitry exchanged letters with Josaph Krokowski, archimandrit of Kievan Lauras and future metropolitan of Kiev. Letters were sent with agents of both hierarchs. This correspondence was devoted to the publication of the “Lives of the Saints” in the Lavra’s typography. There are no evedencies of st. Dimitry writing letteres to members of Chernigov clergy in 1701–1709, although st. John Maximovich archbishop of Chernigov sent his new books to Dimitry of Rostov. However in february of 1704st. Dmitry undertook a journey to Chernigov that left almost no traces in sources. The main evidence is record of Pachomios of Roman, a Moldavian ascetic, about himself meeting Rostov metropolitan in Chernigov in 1704. This trip was an exeptional event and could be connected with the demise of Parthenios Neboza, metropolitan of Holmogory, who died suddenly on 2 january 1704 in Yaroslavl. Author concludes that Dimitry of Rostov in 1701–1709 was not isolated from his old friends and mantained his ties with educated clergy of Little Russia during the years of his Episcopal service in Moscow and Rostov.

  6. Oral Administration of Heat-Killed Lactobacillus gasseri OLL2809 Reduces Cedar Pollen Antigen-Induced Peritoneal Eosinophilia in Mice

    Directory of Open Access Journals (Sweden)

    Toshihiro Sashihara

    2008-01-01

    Conclusions: We demonstrated that the oral administration of heat-killed L. gasseri OLL2809 suppresses eosinophilia via the modulation of Th1/Th2 balance. These observations suggested that heat-killed L. gasseri OLL2809 might potentially ameliorate the increased number of eosinophils in patients with Japanese cedar pollinosis.

  7. HINTS Puerto Rico: Final Report

    Science.gov (United States)

    This final report describes HINTS implementation in Puerto Rico. The report addresses sampling; staffing, training and management of data collection; calling protocol; findings from the CATI Operations, and sample weights.

  8. Active Learning Using Hint Information.

    Science.gov (United States)

    Li, Chun-Liang; Ferng, Chun-Sung; Lin, Hsuan-Tien

    2015-08-01

    The abundance of real-world data and limited labeling budget calls for active learning, an important learning paradigm for reducing human labeling efforts. Many recently developed active learning algorithms consider both uncertainty and representativeness when making querying decisions. However, exploiting representativeness with uncertainty concurrently usually requires tackling sophisticated and challenging learning tasks, such as clustering. In this letter, we propose a new active learning framework, called hinted sampling, which takes both uncertainty and representativeness into account in a simpler way. We design a novel active learning algorithm within the hinted sampling framework with an extended support vector machine. Experimental results validate that the novel active learning algorithm can result in a better and more stable performance than that achieved by state-of-the-art algorithms. We also show that the hinted sampling framework allows improving another active learning algorithm designed from the transductive support vector machine.

  9. A critical review of the most important sources on Dimitris Mitropoulos 1896-1960

    Directory of Open Access Journals (Sweden)

    Siopsi Anastasia

    2003-01-01

    Full Text Available As most important books on Dimitris Mitropoulos should be mentioned those by Apostolos Kostios, William R. Trotter and Takis Kalogeropoulos. Two other editions are also valuable: the correspondence Mitropoulos - Katy Katsoyanis, and the selected texts of the artist. Mitropoulos had difficult relations with his Greek colleagues, especially after his emigration to the United States of America in 1939. At the time when the most important Greek composers strove to create a national school of music he made it clear that he did not like the idea of national music. He developed a neutral or even indifferent attitude towards musical activities in Greece and rarely included Greek compositions in his repertoire.

  10. Lactobacillus bulgaricus OLL1181 activates the aryl hydrocarbon receptor pathway and inhibits colitis

    Science.gov (United States)

    Takamura, Takeyuki; Harama, Daisuke; Fukumoto, Suguru; Nakamura, Yuki; Shimokawa, Naomi; Ishimaru, Kayoko; Ikegami, Shuji; Makino, Seiya; Kitamura, Masanori; Nakao, Atsuhito

    2011-01-01

    Increasing evidence suggests that the aryl hydrocarbon receptor (AhR) pathway has an important role in the regulation of inflammatory responses. Most recently, we have shown that the activation of the AhR pathway by a potent AhR agonist inhibits the development of dextran sodium sulfate (DSS)-induced colitis, a model of human ulcerative colitis, by the induction of prostaglandin E2 (PGE2) in the large intestine. Because several strains of probiotic lactic acid bacteria have been reported to inhibit DSS-induced colitis by unidentified mechanisms, we hypothesized that particular strains of lactic acid bacterium might have the potential to activate the AhR pathway, thereby inhibiting DSS-induced colitis. This study investigated whether there are specific lactic acid bacterial strains that can activate the AhR pathway, and if so, whether this AhR-activating potential is associated with suppression of DSS-induced colitis. By using AhR signaling reporter cells, we found that Lactobacillus bulgaricus OLL1181 had the potential to activate the AhR pathway. OLL1181 also induced the mRNA expression of cytochrome P450 family 1A1 (CYP1A1), a target gene of the AhR pathway, in human colon cells, which was inhibited by the addition of an AhR antagonist, α-naphthoflavon (αNF). In addition, mice treated orally with OLL1181 showed an increase in CYP1A1 mRNA expression in the large intestine and amelioration of DSS-induced colitis. Thus, OLL1181 can induce activation of the intestinal AhR pathway and inhibit DSS-induced colitis in mice. This strain of lactic acid bacterium has therefore the potential to activate the AhR pathway, which may be able to suppress colitis. PMID:21321579

  11. Oral administration of heat-killed Lactobacillus gasseri OLL2809 reduces cedar pollen antigen-induced peritoneal eosinophilia in Mice.

    Science.gov (United States)

    Sashihara, Toshihiro; Ikegami, Shuji; Sueki, Natsuko; Yamaji, Taketo; Kino, Kohsuke; Taketomo, Naoki; Gotoh, Minoru; Okubo, Kimihiro

    2008-12-01

    Lactobacillus gasseri OLL2809 strongly stimulates the production of interleukin (IL)-12 (p70) by innate immune cells. Thus, it is expected to ameliorate allergic diseases. We investigated whether the oral administration of heat-killed L. gasseri OLL2809 suppressed eosinophilia in cedar pollen antigen-challenged mice. BALB/c mice sensitized with Japanese cedar pollen extract were intraperitoneally challenged with the same extract. The mice were orally given heat-killed L. gasseri OLL2809 at doses of 0.5, 1, or 2mg/day throughout the experimental period (21 d). After 24 hours of the challenge, the eosinophil number and cytokine levels in the peritoneal lavage fluid and the serum antigen-specific IgG levels were determined. On administering varying amounts of heat-killed L. gasseri OLL2809, the number of eosinophils among the total number of cells was significantly reduced in all groups. In addition, the eosinophil number significantly decreased, and the eosinophil-suppression rate significantly increased by 44% in the 2-mg group. Although the serum immunoglobulin (Ig) G2a and IgG1 levels were not affected, the IgG2a/IgG1 ratio increased significantly in the 2-mg group compared with that of the control group. Furthermore, the administration of heat-killed L. gasseri OLL2809 resulted in the induction of IL-2 and reduction in granulocyte-macrophage colony-stimulating factor levels in peritoneal lavage fluid. We demonstrated that the oral administration of heat-killed L. gasseri OLL2809 suppresses eosinophilia via the modulation of Th1/Th2 balance. These observations suggested that heat-killed L. gasseri OLL2809 might potentially ameliorate the increased number of eosinophils in patients with Japanese cedar pollinosis.

  12. Complexity hints for economic policy

    CERN Document Server

    Salzano, Massimo

    2007-01-01

    This volume extends the complexity approach to economics. This complexity approach is not a completely new way of doing economics, and that it is a replacement for existing economics, but rather the integration of some new analytic and computational techniques into economists’ bag of tools. It provides some alternative pattern generators, which can supplement existing approaches by providing an alternative way of finding patterns than be obtained by the traditional scientific approach. On this new kind of policy hints can be obtained. The reason why the complexity approach is taking hold now in economics is because the computing technology has advanced. This advance allows consideration of analytical systems that could not previously be considered by economists. Consideration of these systems suggested that the results of the "control-based" models might not extend easily to more complicated systems, and that we now have a method—piggybacking computer assisted analysis onto analytic methods—to start gen...

  13. Enhanced natural killer cell activation by exopolysaccharides derived from yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1.

    Science.gov (United States)

    Makino, Seiya; Sato, Asako; Goto, Ayako; Nakamura, Marie; Ogawa, Miho; Chiba, Yoshika; Hemmi, Jun; Kano, Hiroshi; Takeda, Kazuyoshi; Okumura, Ko; Asami, Yukio

    2016-02-01

    Yogurt is generally recognized as a beneficial food for our health, but research into its physiological effects has focused mainly on intestinal dysfunctions such as constipation and diarrhea. We previously found yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 (hereafter OLL1073R-1) could reduce risks of catching the common cold and flu in human trials. It was assumed that immunostimulatory exopolysaccharide (EPS) produced from OLL1073R-1 play an important role in this context. However, few studies have examined the immunostimulatory effects of traditional Bulgarian yogurts fermented with different strains of lactobacilli and their metabolites. Therefore, we screened 139 L. delbrueckii ssp. bulgaricus strains and identified OLL1073R-1 as the most robust producer of EPS. This strain was also the only strain that induced the production of IFN-γ in vitro. Oral administration of the EPS or yogurt fermented with OLL1073R-1 and Streptococcus thermophilus OLS3059 (OLL1073R-1 yogurt) augmented natural killer (NK) cell activity and induced IFN-γ production in spleen cells in mice, whereas 2 other yogurts fermented with other strains had no effect on NK cell activity. Cellular preparations of the OLL1073R-1 strain also slightly augmented NK cell activity, but were less effective than EPS itself. The EPS-dependent stimulation of NK cell activity was abrogated in IFN-γ knockout mice and in myeloid differentiation factor 88 knockout mice. Furthermore, IFN-γ production from spleen cells stimulated with EPS was completely blocked with both anti-IL-12 and anti-IL-18 antibodies in vitro. These findings suggest that NK cell activation by OLL1073R-1 yogurt is EPS-dependent, occurs via IL-12- and IL-18-mediated IFN-γ production, and requires myeloid differentiation factor 88. We showed that traditional Bulgarian yogurt could exert immunostimulatory effects by selecting starter strains and part of the mechanisms depend on IFN-γ inducible EPS produced

  14. Enhancing the Automatic Generation of Hints with Expert Seeding

    Science.gov (United States)

    Stamper, John; Barnes, Tiffany; Croy, Marvin

    2011-01-01

    The Hint Factory is an implementation of our novel method to automatically generate hints using past student data for a logic tutor. One disadvantage of the Hint Factory is the time needed to gather enough data on new problems in order to provide hints. In this paper we describe the use of expert sample solutions to "seed" the hint generation…

  15. Financial model calibration using consistency hints.

    Science.gov (United States)

    Abu-Mostafa, Y S

    2001-01-01

    We introduce a technique for forcing the calibration of a financial model to produce valid parameters. The technique is based on learning from hints. It converts simple curve fitting into genuine calibration, where broad conclusions can be inferred from parameter values. The technique augments the error function of curve fitting with consistency hint error functions based on the Kullback-Leibler distance. We introduce an efficient EM-type optimization algorithm tailored to this technique. We also introduce other consistency hints, and balance their weights using canonical errors. We calibrate the correlated multifactor Vasicek model of interest rates, and apply it successfully to Japanese Yen swaps market and US dollar yield market.

  16. Structure determination of the neutral exopolysaccharide produced by Lactobacillus delbrueckii subsp. bulgaricus OLL1073R-1.

    Science.gov (United States)

    Van Calsteren, Marie-Rose; Gagnon, Fleur; Nishimura, Junko; Makino, Seiya

    2015-09-02

    The neutral exopolysaccharide (NPS) of Lactobacillus delbrueckii subsp. bulgaricus strain OLL1073R-1 was purified and characterized. The molecular mass was 5.0×10(6) g/mol. Sugar and absolute configuration analyses gave the following composition: d-Glc, 1; d-Gal, 1.5. The NPS was also submitted to periodate oxidation followed by borohydride reduction and Smith degradation. Sugar and methylation analyses, (1)H and (13)C nuclear magnetic resonance, and mass spectrometry of the NPS or of its specifically modified products allowed determining the repeating unit sequence: {2)Glc(α1-3)Glc(β1-3)[Gal(β1-4)]Gal(β1-4)Gal(α1-}n. The structure is compared to that of exopolysaccharides produced by other Lactobacillus bulgaricus strains. Copyright © 2015. Published by Elsevier Ltd.

  17. Effects of Lactobacillus plantarum Strain OLL2712 Culture Conditions on the Anti-inflammatory Activities for Murine Immune Cells and Obese and Type 2 Diabetic Mice.

    Science.gov (United States)

    Toshimitsu, T; Ozaki, S; Mochizuki, J; Furuichi, K; Asami, Y

    2017-04-01

    Studies on the health-promoting effects of lactic acid bacteria (LAB) are numerous, but few provide examples of the relationship between LAB function and culture conditions. We verified the effect of differences in culture conditions on Lactobacillus plantarum OLL2712 functionality; this strain exhibits anti-inflammatory activity and preventive effects against metabolic disorders. We measured interleukin-10 (IL-10) and IL-12 production in murine immune cells treated with OLL2712 cells prepared under various culture conditions. The results showed that the IL-10-inducing activities of OLL2712 cells on murine immune cells differed dramatically between OLL2712 groups at different culture phases and using different culture medium components, temperatures, and neutralizing pHs. In particular, exponential-phase cells had much more IL-10-inducing activity than stationary-phase cells. We confirmed that the Toll-like receptor 2 (TLR2) stimulation activity of OLL2712 cells depended on culture conditions in conjunction with IL-10-inducing activity. We also demonstrated functional differences by culture phases in vivo ; OLL2712 cells at exponential phase had more anti-inflammatory activity and anti-metabolic-disorder effects on obese and diabetic mice than those by their stationary-phase counterparts. These results suggest that culture conditions affect the functionality of anti-inflammatory LAB. IMPORTANCE While previous studies demonstrated that culture conditions affected the immunomodulatory properties of lactic acid bacteria (LAB), few have comprehensively investigated the relationship between culture conditions and LAB functionality. In this study, we demonstrated several culture conditions of Lactobacillus plantarum OLL2712 for higher anti-inflammatory activity. We also showed that culture conditions concretely influenced the health-promoting functions of OLL2712 in vivo , particularly against metabolic disorders. Further, we characterized a novel mechanism by which

  18. Astrophysical hints of axion-like particles

    Science.gov (United States)

    Roncadelli, M.; Galanti, G.; Tavecchio, F.; Bonnoli, G.

    2015-01-01

    After reviewing three astrophysical hints of the existence of axion-like particles (ALPs), we describe in more detail a new similar hint involving flat spectrum radio quasars (FSRQs). Detection of FSRQs above about 20GeV pose a challenge to very-high-energy (VHE) astrophysics, because at those energies the ultraviolet emission from their broad line region should prevent photons produced by the central engine to leave the source. Although a few astrophysical explanations have been put forward, they are totally ad hoc. We show that a natural explanation instead arises within the conventional models of FSRQs provided that photon-ALP oscillations occur inside the source. Our analysis takes the FSRQ PKR 1222+206 as an example, and it looks tantalizing that basically the same choice of the free model parameters adopted in this case is consistent with those that provide the other three hints of the existence of ALPs.

  19. Effect of Formic Acid on Exopolysaccharide Production in Skim Milk Fermentation by Lactobacillus delbrueckii subsp. bulgaricus OLL1073R-1.

    Science.gov (United States)

    Nishimura, Junko; Kawai, Yasushi; Aritomo, Ryota; Ito, Yoshiyuki; Makino, Seiya; Ikegami, Shuji; Isogai, Emiko; Saito, Tadao

    2013-01-01

    In yogurt, the formation of formate by Streptococcus thermophilus stimulates the activity of Lactobacillus delbrueckii subsp. bulgaricus (L. bulgaricus). However, there have been no reports how formic acid acts on the exopolysaccharide (EPS) production of L. bulgaricus. Here, the effect of formate on the EPS production in skim milk by L. bulgaricus OLL1073R-1 was investigated. After incubation for 24 hr with 100 mg/l formate, cell proliferation and lactic acid production were accelerated. The viable and total cell numbers were increased about ten- and four-fold, respectively. The amount of EPS in culture with formate (~116 µg/ml) was also four-fold greater than that of the control (~27 µg/ml). Although elongation of cells was observed at 6 hr of cultivation in both cultures, cells cultivated with formate returned to a normal shape after incubation for 24 hr. The sensitivity to cell wall hydrolase and composition of surface layer proteins, as well as the cell membrane fatty acid composition of L. bulgaricus OLL1073R-1, were not influenced by formate. However, differences were observed in intracellular fatty acid compositions and sensitivity to antibiotics. Cell length and surface damage returned to normal in cultures with formate. These observations suggest that formic acid is necessary for normal cell growth of L. bulgaricus OLL1073R-1 and higher EPS production.

  20. Oral administration of Lactobacillus delbrueckii subspecies bulgaricus OLL1073R-1 suppresses inflammation by decreasing interleukin-6 responses in a murine model of atopic dermatitis.

    Science.gov (United States)

    Kano, Hiroshi; Kita, Junko; Makino, Seiya; Ikegami, Shuji; Itoh, Hiroyuki

    2013-06-01

    The oral intake of Lactobacillus spp. can provide beneficial effects to the host by modulating the immune response. Atopic dermatitis (AD) is an allergic inflammatory disease mediated by various immune responses. In this study, we examined the effect of a Lactobacillus strain, Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 (OLL1073R-1), on AD development in a murine model of AD that was developed by the topical application of mite antigen in NC/Nga mice. The oral intake of heat-killed OLL1073R-1 cells inhibited both the development of dermatitis and the elevation of an acute inflammation marker, serum amyloid A. Another bacterial strain, Lactobacillus rhamnosus OLL2984, exerted no inhibitory effects on dermatitis. The oral intake of heat-killed OLL1073R-1 cells also attenuated secretion of IL-6 from lymph node cells in response to mite antigen and reduced IL-6 levels in inflamed tissues, such as auricles. Production of IFN-γ or IL-4 was not influenced by OLL1073R-1 intake. We also found that inhibition of IL-6 signaling by gp130-Fc (a fusion protein consisting of the extracellular portion of glycoprotein 130 fused to the Fc region of human IgG1) markedly decreased the severity of dermatitis in NC/Nga mice. Moreover, secretion of IL-6 by lymph node cells was augmented in NC/Nga mice compared with that in BALB/c mice. These results indicate that IL-6 plays an essential role in the development of dermatitis in the NC/Nga mouse model of AD, and that OLL1073R-1 inhibits dermatitis, at least in part, by suppressing the IL-6 response. Copyright © 2013 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  1. Eating Hints: Before, During, and After Cancer Treatment

    Science.gov (United States)

    ... Publications Reports Eating Hints: Before, during, and after Cancer Treatment Eating Hints is for people who are having or are about to have cancer treatment. Family and friends may also want to read ...

  2. Hants Hint - kõigi ihaldatud kaalukeel / Hants Hint ; interv. Erik Gamzejev

    Index Scriptorium Estoniae

    Hint, Hants

    2002-01-01

    Ilmunud ka: Severnoje Poberezhje : Laupäev 26. okt. lk. 3. Res Publica Ida-Viru piirkonna juht Hants Hint: me oleme põhimõtteliselt valmis kõigi poliitiliste jõududega koostööd tegema. Autor: Res Publica

  3. Kunstiülikool on nagu pioneeride palee kunstiring / Vilen Künnapu, Meeli Truu, Eerik Olle...[jt.] ; interv. Gea Velthut-Sokka

    Index Scriptorium Estoniae

    1999-01-01

    Arhitektid V. Künnapu ja M. Truu, sisearhitektid I.-E. Schneider, E. Olle ja M. Peri ning kinnisvaraarendaja A. Aavik vastavad küsimustele, millises ülikoolis nad omandaksid eriala, kui nad oleksi praegu tudengid, Eestis saadava hariduse konkurentsivõimelisuse kohta maailmas, mida nad tahaksid praegu enda täiendamiseks õppida?

  4. Experimental hint for gravitational CP violation

    Energy Technology Data Exchange (ETDEWEB)

    Gharibyan, Vahagn [Deutsches Elektronen-Synchrotron, Hamburg (Germany). MDI Group

    2016-01-15

    An equality of particle and antiparticle gravitational interactions holds in general relativity and is supported by indirect observations. Gravity dependence on rotation or spin direction is experimentally constrained only at low energies. Here a method based on high energy Compton scattering is developed to measure the gravitational interaction of accelerated charged particles. Within that formalism the Compton spectra measured at HERA rule out the positron's anti-gravity and hint for a gravitational CP violation around 13 GeV energies, at a maximal level of 1.3±0.2% for the charge and 0.68±0.09% for the space parity. A stronger gravitational coupling to left helicity electrons relative to right helicity positrons is detected.

  5. Experimental hint for gravitational CP violation

    International Nuclear Information System (INIS)

    Gharibyan, Vahagn

    2016-01-01

    An equality of particle and antiparticle gravitational interactions holds in general relativity and is supported by indirect observations. Gravity dependence on rotation or spin direction is experimentally constrained only at low energies. Here a method based on high energy Compton scattering is developed to measure the gravitational interaction of accelerated charged particles. Within that formalism the Compton spectra measured at HERA rule out the positron's anti-gravity and hint for a gravitational CP violation around 13 GeV energies, at a maximal level of 1.3±0.2% for the charge and 0.68±0.09% for the space parity. A stronger gravitational coupling to left helicity electrons relative to right helicity positrons is detected.

  6. Increased anxiety-related behaviour in Hint1 knockout mice.

    Science.gov (United States)

    Varadarajulu, Jeeva; Lebar, Maria; Krishnamoorthy, Gurumoorthy; Habelt, Sonja; Lu, Jia; Bernard Weinstein, I; Li, Haiyang; Holsboer, Florian; Turck, Christoph W; Touma, Chadi

    2011-07-07

    Several reports have implicated a role for the histidine triad nucleotide-binding protein-1 (Hint1) in psychiatric disorders. We have studied the emotional behaviour of male Hint1 knockout (Hint1 KO) mice in a battery of tests and performed biochemical analyses on brain tissue. The behavioural analysis revealed that Hint1 KO mice exhibit an increased emotionality phenotype compared to wildtype (WT) mice, while no significant differences in locomotion or general exploratory activity were noted. In the elevated plus-maze (EPM) test, the Hint1 KO animals entered the open arms of the apparatus less often than WT littermates. Similarly, in the dark-light box test, Hint1 KO mice spent less time in the lit compartment and the number of entries were reduced, which further confirmed an increased anxiety-related behaviour. Moreover, the Hint1 KO animals showed significantly more struggling and less floating behaviour in the forced swim test (FST), indicating an increased emotional arousal in aversive situations. Hint1 is known as a protein kinase C (PKC) interacting protein. Western blot analysis showed that PKCγ expression was elevated in Hint1 KO compared to WT mice. Interestingly, PKCγ mRNA levels of the two groups did not show a significant difference, implying a post-transcriptional PKCγ regulation. In addition, PKC enzymatic activity was increased in Hint1 KO compared to WT mice. In summary, our results indicate a role for Hint1 and PKCγ in modulating anxiety-related and stress-coping behaviour in mice. Copyright © 2011 Elsevier B.V. All rights reserved.

  7. Exopolysaccharides from Lactobacillus delbrueckii OLL1073R-1 modulate innate antiviral immune response in porcine intestinal epithelial cells.

    Science.gov (United States)

    Kanmani, Paulraj; Albarracin, Leonardo; Kobayashi, Hisakazu; Iida, Hikaru; Komatsu, Ryoya; Humayun Kober, A K M; Ikeda-Ohtsubo, Wakako; Suda, Yoshihito; Aso, Hisashi; Makino, Seiya; Kano, Hiroshi; Saito, Tadao; Villena, Julio; Kitazawa, Haruki

    2018-01-01

    Previous studies demonstrated that the extracellular polysaccharides (EPSs) produced by Lactobacillus delbrueckii OLL1073R-1 (LDR-1) improve antiviral immunity, especially in the systemic and respiratory compartments. However, it was not studied before whether those EPSs are able to beneficially modulate intestinal antiviral immunity. In addition, LDR-1-host interaction has been evaluated mainly with immune cells while its interaction with intestinal epithelial cells (IECs) was not addressed before. In this work, we investigated the capacity of EPSs from LDR-1 to modulate the response of porcine IECs (PIE cells) to the stimulation with the Toll-like receptor (TLR)-3 agonist poly(I:C) and the role of TLR2, TLR4, and TLR negative regulators in the immunoregulatory effect. We showed that innate immune response triggered by TLR3 activation in porcine IECs was differentially modulated by EPS from LDR-1. EPSs treatment induced an increment in the expression of interferon (IFN)-α and IFN-β in PIE cells after the stimulation with poly(I:C) as well as the expression of the antiviral factors MxA and RNase L. Those effects were related to the reduced expression of A20 in EPS-treated PIE cells. EPS from LDR-1 was also able to reduce the expression of IL-6 and proinflammatory chemokines. Although further in vivo studies are needed, our results suggest that these EPSs or a yogurt fermented with LDR-1 have potential to improve intestinal innate antiviral response and protect against intestinal viruses. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. An analytical model of the HINT performance metric

    Energy Technology Data Exchange (ETDEWEB)

    Snell, Q.O.; Gustafson, J.L. [Scalable Computing Lab., Ames, IA (United States)

    1996-10-01

    The HINT benchmark was developed to provide a broad-spectrum metric for computers and to measure performance over the full range of memory sizes and time scales. We have extended our understanding of why HINT performance curves look the way they do and can now predict the curves using an analytical model based on simple hardware specifications as input parameters. Conversely, by fitting the experimental curves with the analytical model, hardware specifications such as memory performance can be inferred to provide insight into the nature of a given computer system.

  9. New physics hints in B decays and collider outlook

    Indian Academy of Sciences (India)

    There are currently two hints for new physics involving CP violation in → transitions: ≡ - / ≠ 0, and difference in direct CP asymmetry Δ A K π ≡ A K + π 0 − A K + π ≠ 0 . We explore the two scenarious with a large and unique new CP phase in ← tansitions. Motivated by ≠ 0, we update on the ...

  10. Gaze-based hints during child-robot gameplay

    NARCIS (Netherlands)

    Mwangi, E.; Barakova, Emilia I.; Diaz, M.L.Z.; Mallofre, A.C.; Rauterberg, G.W.M.; Kheddar, A.; Yoshida, E.; Sam Ge, S.; Suzuki, K.; Cabibihan, J.J.; Eyssel, F.; He, H.

    2017-01-01

    This paper presents a study that examines whether gaze hints provided by a robot tutor influences the behavior of children in a card matching game. In this regard, we conducted a within-subjects experiment, in which children played a card game “Memory” in the presence of a robot tutor in two

  11. Observational Hints of a Pre--Inflationary Scale?

    CERN Document Server

    Gruppuso, A.

    2015-09-28

    We argue that the lack of power exhibited by cosmic microwave background (CMB) anisotropies at large angular scales might be linked to the onset of inflation. We highlight observational features and theoretical hints that support this view, and present a preliminary estimate of the physical scale that would underlie the phenomenon.

  12. Oral lichen planus (OLP), oral lichenoid lesions (OLL), oral dysplasia, and oral cancer: retrospective analysis of clinicopathological data from 2002-2011.

    Science.gov (United States)

    Casparis, S; Borm, J M; Tektas, S; Kamarachev, J; Locher, M C; Damerau, G; Grätz, K W; Stadlinger, B

    2015-06-01

    This 10-year retrospective study analyzed the incidence of malignant transformation of oral lichen planus (OLP). The study also included dysplasia and oral lichenoid lesion (OLL) in the initial biopsy as a potential differential diagnosis. A total of 692 scalpel biopsies were taken from 542 patients (207 [38.2%] men and 335 [61.8%] women). Clinical and histopathological parameters were analyzed. The parameters gender (p = 0.022) and smoking behavior (p oral squamous cell carcinoma (OSCC). Smoking and joint disease appeared to be significant risk factors. Treatment with tretinoin in different concentrations (0.005-0.02%) significantly improved diagnosis. Twelve patients (8 female, 4 male) showed malignant transformation to OSCC within an average period of 1.58 years. The malignant transformation rate (MTR) was higher for OLL (4.4%) than OLP (1.2%). If the first biopsy showed intraepithelial neoplasia, the risk of developing OSCC increased (by 3.5% for squamous intraepithelial neoplasia (SIN) II and by 6.7% for SIN III). Although we cannot rule out that OLP is a premalignant oral condition, we can confirm that OLP had the lowest MTR of all diagnoses.

  13. A two-Higgs-doublet model facing experimental hints

    Directory of Open Access Journals (Sweden)

    Crivellin Andreas

    2016-01-01

    Full Text Available Physics beyond the Standard Model has so far eluded our experimental probes. Nevertheless, a number of interesting anomalies have accumulated that can be taken as hints towards new physics: BaBar, Belle, and LHCb have found deviations of approximately 3:8σ in B → Dτν and B → D*τν; the anomalous magnetic moment of the muon differs by about 3σ from the theoretic prediction; the branching ratio for τ → μνν is about 2σ above the Standard Model expectation; and CMS and ATLAS found hints for a non-zero decay rate of h → μτ at 2.6σ. Here we consider these processes within a lepton-specific two-Higgs doublet model with additional non-standard Yukawa couplings and show how (and which of these excesses can be accommodated.

  14. HINT computation of LHD equilibrium with zero rotational transform surface

    International Nuclear Information System (INIS)

    Kanno, Ryutaro; Toi, Kazuo; Watanabe, Kiyomasa; Hayashi, Takaya; Miura, Hideaki; Nakajima, Noriyoshi; Okamoto Masao

    2004-01-01

    A Large Helical Device equilibrium having a zero rotational transform surface is studied by using the three dimensional MHD equilibrium code, HINT. We find existence of the equilibrium but with formation of the two or three n=0 islands composing a homoclinic-type structure near the center, where n is a toroidal mode number. The LHD equilibrium maintains the structure, when the equilibrium beta increases. (author)

  15. Eestlased kinometropolis / Olle Mirme

    Index Scriptorium Estoniae

    Mirme, Olle, 1973-

    2002-01-01

    Berliini 52. filmifestivali Panorama valikprogrammi kavas olnud Peeter Simmi Eesti-Läti ühisfilm "Head käed" saavutas hea publikuedu ning jagas Manfred Salzgeberi auhinda, mis on mõeldud subtiitrite tegemiseks filmi levitamisel euroopa ekraanidele. Žürii tõstis esile Toomas Raudami stsenaariumi originaalsust ja P. Simmi režiid. Pikemalt ka pressikonverentsist

  16. [Peripheral vertigo versus central vertigo. Application of the HINTS protocol].

    Science.gov (United States)

    Batuecas-Caletrío, Ángel; Yáñez-González, Raquel; Sánchez-Blanco, Carmen; González-Sánchez, Enrique; Benito, José; Gómez, José Carlos; Santa Cruz-Ruiz, Santiago

    2014-10-16

    One of the most important dilemmas concerning vertigo in emergency departments is its differential diagnosis. There are highly sensitive warning signs in the examination that can put us on the path towards finding ourselves before a case of central vertigo. To determine how effective the application of the HINTS protocol is in the diagnosis of cerebrovascular accidents that mimics peripheral vertigo. We conducted a descriptive observation-based study on patients admitted to hospital with a diagnosis of acute vestibular syndrome in the emergency department. All the patients were monitored on a day-to-day basis until their symptoms improved, with information about nystagmus, the oculocephalic manoeuvre and the skew test. The results from the magnetic resonance imaging study were compared with the alteration of any of those three signs during the time the patient was hospitalised. Altogether 91 patients were examined, with a mean age of 55.8 years. A cerebrovascular accident was observed in eight cases. Of these (mean age: 71 years), in seven of them there were alterations in some of the HINTS signs, and in one case the study was normal (sensitivity: 0.88; specificity: 0.96). All of them had some vascular risk factor. Faced with a patient who visits the emergency department with an acute vestibular syndrome, a suitably directed examination is essential to be able to establish the differential diagnosis between peripheral and central pathology, since some cerebrovascular accidents can present with the appearance of acute vertigo. Applying a protocol like HINTS makes it possible to suspect the central pathology with a high degree of sensitivity and specificity.

  17. Who is Jesus Christ for the Ruthenian and Russian Saints? A Theological Exploration of St Dimitry Rostovsky’s The Lives of the Saints

    Directory of Open Access Journals (Sweden)

    Krzysztof Leśniewski

    2014-12-01

    Full Text Available Christian hagiography reveals not only the facts of life of individual saints, but first of all, it is a description of theexperience of God loving mankind. From the beginning of Christianity, of great importance in building faith, hope andlove had had stories about those believers who responded with a particular radicalism for the prevenient love of God inthe Trinity of Persons. These stories have been written in various forms of literature.Author in the introductory part of the article introduces into the lives of the saints and their role in the Ruthenian andRussian Orthodoxy. Essentially he focuses on presenting The Menaia edited by St Dimitry Rostovski. This book waspublished in the years 1711 to 1718 in Old Church Slavonic. At the beginning of the twentieth century, it has been rewrittenand translated into Russian. This monumental work appeared in the years 1903-1911 under the title The Lives of theSaints. It has been a rich source of information for researchers from many disciplines.From a theological point of view, the author studied The Lives of the Saints in order to find direct references to theperson and teaching of Jesus Christ. For this purpose, he analyzed quotations from the New Testament, especially fromthe Gospel, referring directly to the Person and teaching of Jesus Christ, as well as the prayers addressed to Him. In hisanalysis, he searched for answers to the questions: Who is Jesus Christ for the Ruthenian and Russian saints, and whatkind of His images predominate in The Lives of the Saints.The first part of the article, on the basis of source texts, indicates personal qualities of Jesus Christ. The Savior hasbeen experienced by the Ruthenian and Russian saints as God who is close to man, the blessed King, the best Lord, theComforter of the crying, the Light, the merciful God, and the Foundation of all good. The image of Christ as sinless,innocent suffering and merciful shines especially in the devotion of Saints Passion

  18. HINT-KB: The human interactome knowledge base

    KAUST Repository

    Theofilatos, Konstantinos A.

    2012-01-01

    Proteins and their interactions are considered to play a significant role in many cellular processes. The identification of Protein-Protein interactions (PPIs) in human is an open research area. Many Databases, which contain information about experimentally and computationally detected human PPIs as well as their corresponding annotation data, have been developed. However, these databases contain many false positive interactions, are partial and only a few of them incorporate data from various sources. To overcome these limitations, we have developed HINT-KB (http://150.140.142.24:84/Default.aspx) which is a knowledge base that integrates data from various sources, provides a user-friendly interface for their retrieval, estimates a set of features of interest and computes a confidence score for every candidate protein interaction using a modern computational hybrid methodology. © 2012 IFIP International Federation for Information Processing.

  19. [Dimitri Steinke: Die Zivilrechtsordnungen des Baltikums unter dem Einfluss ausländischer, insbesondere deutscher Rechtsquellen. (Osnabrücker Schriften zur Rechtsgeschichte, Bd. 16.) V&R unipress. Göttingen 2009. 243 S. ISBN 978-3-89971-573-6] / M

    Index Scriptorium Estoniae

    Luts-Sootak, Marju, 1966-

    2011-01-01

    Arvustus: Dimitri Steinke. Die Zivilrechtsordnungen des Baltikums unter dem Einfluss ausländischer, insbesondere deutscher Rechtsquellen. (Osnabrücker Schriften zur Rechtsgeschichte ; 16). Göttingen, 2009

  20. Olle Höök Lectureship 2015: The World Health Organization's paradigm shift and implementation of the International Classification of Functioning, Disability and Health in rehabilitation.

    Science.gov (United States)

    Stucki, Gerold

    2016-06-13

    The World Health Organization's (WHO) paradigm shift, implied by the launch of the International Classification of Functioning, Disability and Health (ICF), is inextricably entwined with the emergence of rehabilitation as a key health strategy of the 21st century. To enable health systems to scale up rehabilitation we must spearhead the implementation of the ICF in rehabilitation towards its system-wide implementation in the healthcare system at large. In this essay, based on the Olle Höök lecture 20151, it is argued that the launch of the ICF in 2001 represents a paradigm shift, as it has enabled the WHO to more comprehensively act on its mandate and has guided WHO policies to shape the health system in response to population functioning needs. It is shown that this paradigm shift has important implications for rehabilitation, including its conceptualization and scientific methods. A prerequisite for the system-wide implementation of the ICF in clinical practice, policy, and research, is the availability of practical tools that allow for the universal and standardized description of functioning. Finally, some reflections are presented on how we may foster the system-wide implementation of the ICF by applying approaches from the implementation sciences.

  1. Understanding Attention to Adaptive Hints in Educational Games: An Eye-Tracking Study

    Science.gov (United States)

    Conati, Cristina; Jaques, Natasha; Muir, Mary

    2013-01-01

    This paper presents a user study that investigates the factors affecting student attention to user-adaptive hints during interaction with an educational computer game. The study focuses on Prime Climb, an educational game designed to provide individualized support for learning number factorization skills in the form of textual hints based on a…

  2. Particle Swarm Optimization algorithms for geophysical inversion, practical hints

    Science.gov (United States)

    Garcia Gonzalo, E.; Fernandez Martinez, J.; Fernandez Alvarez, J.; Kuzma, H.; Menendez Perez, C.

    2008-12-01

    PSO is a stochastic optimization technique that has been successfully used in many different engineering fields. PSO algorithm can be physically interpreted as a stochastic damped mass-spring system (Fernandez Martinez and Garcia Gonzalo 2008). Based on this analogy we present a whole family of PSO algorithms and their respective first order and second order stability regions. Their performance is also checked using synthetic functions (Rosenbrock and Griewank) showing a degree of ill-posedness similar to that found in many geophysical inverse problems. Finally, we present the application of these algorithms to the analysis of a Vertical Electrical Sounding inverse problem associated to a seawater intrusion in a coastal aquifer in South Spain. We analyze the role of PSO parameters (inertia, local and global accelerations and discretization step), both in convergence curves and in the a posteriori sampling of the depth of an intrusion. Comparison is made with binary genetic algorithms and simulated annealing. As result of this analysis, practical hints are given to select the correct algorithm and to tune the corresponding PSO parameters. Fernandez Martinez, J.L., Garcia Gonzalo, E., 2008a. The generalized PSO: a new door to PSO evolution. Journal of Artificial Evolution and Applications. DOI:10.1155/2008/861275.

  3. New physics hints in Β decays and collider outlook

    International Nuclear Information System (INIS)

    Hou, George W.S.

    2006-01-01

    There are currently two hints for new physics involving CP violation in b →s transitions: ΔS ≡ S f - S J/ ψK ≠ 0, and difference in direct CP asymmetry ΔA Kπ ≡ A K + π 0 - A K + π - ≠0. We explore the two scenarios with a large and unique new CP phase in b s transitions. Motivated by ΔS ≠ 0, we update on the right-handed strange beauty squark sb 1R at TeV scale. Motivated by ΔA Kπ ≠ 0, we explore sequential fourth generation t and b quarks. Both scenarios can survive constraints such as SM level b→sγ, sll and Β s mixing, and predict sizable CP violation in Β s mixing. The fourth generation picture predicts sizable K L → π 0 νν. Direct search for sb R , b' and t' at hadronic colliders, such as Tevatron Run II and LHC, can complement further CP violation studies at these machines, as well as at the future Super Β factory. (author)

  4. HinT proteins and their putative interaction partners in Mollicutes and Chlamydiaceae

    Directory of Open Access Journals (Sweden)

    Hegemann Johannes H

    2005-05-01

    Full Text Available Background HinT proteins are found in prokaryotes and eukaryotes and belong to the superfamily of HIT proteins, which are characterized by an histidine-triad sequence motif. While the eukaryotic variants hydrolyze AMP derivates and modulate transcription, the function of prokaryotic HinT proteins is less clearly defined. In Mycoplasma hominis, HinT is concomitantly expressed with the proteins P60 and P80, two domains of a surface exposed membrane complex, and in addition interacts with the P80 moiety. Results An cluster of hitABL genes, similar to that of M. hominis was found in M. pulmonis, M. mycoides subspecies mycoides SC, M. mobile and Mesoplasma florum. RT-PCR analyses provided evidence that the P80, P60 and HinT homologues of M. pulmonis were polycistronically organized, suggesting a genetic and physical interaction between the proteins encoded by these genes in these species. While the hit loci of M. pneumoniae and M. genitalium encoded, in addition to HinT, a protein with several transmembrane segments, the hit locus of Ureaplasma parvum encoded a pore-forming protein, UU270, a P60 homologue, UU271, HinT, UU272, and a membrane protein of unknown function, UU273. Although a full-length mRNA spanning the four genes was not detected, amplification of all intergenic regions from the center of UU270 to the end of UU273 by RT-PCR may be indicative of a common, but unstable mRNA. In Chlamydiaceae the hit gene is flanked upstream by a gene predicted to encode a metal dependent hydrolase and downstream by a gene putatively encoding a protein with ARM-repeats, which are known to be involved in protein-protein interactions. In RT-PCR analyses of C. pneumoniae, regions comprising only two genes, Cp265/Cp266 and Cp266/Cp267 were able to be amplified. In contrast to this in vivo interaction analysis using the yeast two-hybrid system and in vitro immune co-precipitation revealed an interaction between Cp267, which contains the ARM repeats, Cp265, the

  5. Mediki postojali za sebja / Dimitri Klenski

    Index Scriptorium Estoniae

    Klenski, Dimitri, 1945-

    2007-01-01

    Autor nimetab põhjusi, miks rahvas suhtus meedikute streigiplaani ükskõikselt, ning käsitleb rahva hulgas tekkinud valearusaamu, mis on seotud tervishoiu finantseerimise ja arstide palgatõusunõudega

  6. Vene keele 1. suvekool / Dimitri Mironov

    Index Scriptorium Estoniae

    Mironov, Dimitri

    2001-01-01

    2001.a. suvel korraldas TPÜ slaavi filoloogia osakond koostöös välissuhete osakonnaga vene keele suvekooli, mis oli mõeldud välisüliõpilastele. Kaks ja pool nädalat kestnud kursuste jooksul õppisid tudengid Soomest, Inglismaalt ja Hispaaniast intensiivselt vene keelt ning osalesid vene kultuuri tutvustavas programmis

  7. Hint2, the mitochondrial nucleoside 5'-phosphoramidate hydrolase; properties of the homogeneous protein from sheep (Ovis aries) liver.

    Science.gov (United States)

    Bretes, Ewa; Wojdyła-Mamoń, Anna M; Kowalska, Joanna; Jemielity, Jacek; Kaczmarek, Renata; Baraniak, Janina; Guranowski, Andrzej

    2013-01-01

    Adenosine 5'-phosphoramidate (NH2-pA) is a rare natural nucleotide and its biochemistry and biological functions are poorly recognized. All organisms have proteins that may be involved in the catabolism of NH2-pA. They are members of the HIT protein family and catalyze hydrolytic splitting of NH2-pA to 5'-AMP and ammonia. At least five HIT proteins have been identified in mammals; however, the enzymatic and molecular properties of only Fhit and Hint1 have been comprehensively studied. Our study focuses on the Hint2 protein purified by a simple procedure to homogeneity from sheep liver mitochondrial fraction (OaHint2). Hint1 protein was also prepared from sheep liver (OaHint1) and the molecular and kinetic properties of the two proteins compared. Both function as homodimers and behave as nucleoside 5'-phosphoramidate hydrolases. The molecular mass of the OaHint2 monomer is 16 kDa and that of the OaHint1 monomer 14.9 kDa. Among potential substrates studied, NH2-pA appeared to be the best; the Km and kcat values estimated for this compound are 6.6 μM and 68.3 s⁻¹, and 1.5 μM and 11.0 s⁻¹ per natively functioning dimer of OaHint2 and OaHint1, respectively. Studies of the rates of hydrolysis of different NH2-pA derivatives show that Hint2 is more specific towards compounds with a P-N bond than Hint1. The thermostability of these two proteins is also compared.

  8. Interaction Networks: Generating High Level Hints Based on Network Community Clustering

    Science.gov (United States)

    Eagle, Michael; Johnson, Matthew; Barnes, Tiffany

    2012-01-01

    We introduce a novel data structure, the Interaction Network, for representing interaction-data from open problem solving environment tutors. We show how using network community detecting techniques are used to identify sub-goals in problems in a logic tutor. We then use those community structures to generate high level hints between sub-goals.…

  9. Pigeons (Columba livia) know when they will need hints: prospective metacognition for reference memory?

    Science.gov (United States)

    Iwasaki, Sumie; Watanabe, Sota; Fujita, Kazuo

    2018-03-01

    Despite their impressive cognitive abilities, avian species have shown less evidence for metacognition than mammals. We suspect that commonly used tasks such as matching to sample might be too demanding to allow metacognitive processing within birds' working memory. Here, we examined whether pigeons could control their behavior as a function of knowledge levels on a three-item sequence learning task, a reference memory task supposedly requiring fewer working memory resources. The experiment used two types of lists differing in familiarity. One was familiar to the pigeons through repeated exposure, whereas the other was novel in every new session. In test sessions, pigeons could choose between a trial with a hint specifying the next item to peck and one with no hint. However, successful responses in trials with a hint resulted in lowered rates of primary reinforcement: .60 in the first test and .75 in the second. Results showed that two of four pigeons chose the trial with a hint significantly more often before receiving a novel list than the familiar list in the four sessions of the first test, and three did so in the second test. Impressively, one bird showed robust evidence in the very first sessions in both tests. These results suggest that pigeons may monitor their long-term knowledge states and thereby control their environment before starting to solve a task.

  10. Can children take advantage of nao gaze-based hints during gameplay?

    NARCIS (Netherlands)

    Mwangi, E.N.; Diaz, M.; Barakova, E.I.; Catala, A.; Rauterberg, G.W.M.

    2017-01-01

    This paper presents a study that analyzes the effects of robots' gaze hints on children's performance in a card-matching game. We conducted a within-subjects study, in which children played a card matching game "Memory" in the presence of a robot tutor in two sessions. In one session, the robot gave

  11. Theory of mind in a first-episode psychosis population using the Hinting Task.

    Science.gov (United States)

    Lindgren, Maija; Torniainen-Holm, Minna; Heiskanen, Inkeri; Voutilainen, Greta; Pulkkinen, Ulla; Mehtälä, Tuukka; Jokela, Markus; Kieseppä, Tuula; Suvisaari, Jaana; Therman, Sebastian

    2018-05-01

    Deficiencies in theory of mind (ToM) are common in psychosis and may largely explain impaired social functioning. Currently, it is unclear whether impairments in ToM are explained by the more general cognitive deficits related to psychosis or whether ToM is impaired in psychosis independently of other cognitive deficits. This study examined ToM using the Hinting Task in young adults (n = 66) with first-episode psychosis and matched controls (n = 62). The participants were administered a broad neuropsychological assessment. Participants with psychosis performed worse than controls on the Hinting Task. However, 75% of the variance between the groups was explained by general cognitive deficits, especially impaired processing speed and episodic memory. Hinting Task performance of the best functioning patient group did not differ from that of the control group. When the psychosis group was divided according to diagnosis, the Hinting Task difference between individuals with schizophrenia and controls remained significant even when general cognitive performance was controlled for, suggesting specific verbal ToM deficits in schizophrenia. In contrast, those with other psychotic disorders did not differ from controls. Our results suggest that ToM deficits can be seen in early phases of psychotic disorders, schizophrenia in particular, and are partly independent of other cognitive functions. Copyright © 2018 Elsevier B.V. All rights reserved.

  12. Pedagogical Agent Gestures to Improve Learner Comprehension of Abstract Concepts in Hints

    Science.gov (United States)

    Martins, Igor; de Morais, Felipe; Schaab, Bruno; Jaques, Patricia

    2016-01-01

    In most Intelligent Tutoring Systems, the help messages (hints) are not very clear for students as they are only presented textually and have little connection with the task elements. This can lead to students' undesired behaviors, like gaming the system, associated with low performance. In this paper, the authors aim at evaluating if the gestures…

  13. Res Publicas käärib mäss / Hants Hint

    Index Scriptorium Estoniae

    Hint, Hants

    2002-01-01

    Res Publica eestseisuse liige ja Ida-Viru piirkonna esimees Hants Hint vastab küsimustele Res Publica ja Keskerakonna võimuliidu moodustamisega tekkinud skandaali, Res Publica esimehe Juhan Partsiga kohtumise kohta. Vt. samas: "Korbi toetajaid ootab hukkamõist"

  14. Data-Driven Hint Generation in Vast Solution Spaces: A Self-Improving Python Programming Tutor

    Science.gov (United States)

    Rivers, Kelly; Koedinger, Kenneth R.

    2017-01-01

    To provide personalized help to students who are working on code-writing problems, we introduce a data-driven tutoring system, ITAP (Intelligent Teaching Assistant for Programming). ITAP uses state abstraction, path construction, and state reification to automatically generate personalized hints for students, even when given states that have not…

  15. Stoic Behavior Hypothesis in Hint Seeking and Development of Reversi Learning Environment as Work Bench for Investigation

    Science.gov (United States)

    Miwa, Kazuhisa; Kojima, Kazuaki; Terai, Hitoshi

    2014-01-01

    Tutoring systems provide students with various types of on-demand and context-sensitive hints. Students are required to consciously adapt their help-seeking behavior, proactively seek help in some situations, and solve problems independently without supports in other situations. We define the latter behavior as stoic behavior in hint seeking. In…

  16. HINTS outperforms ABCD2 to screen for stroke in acute continuous vertigo and dizziness.

    Science.gov (United States)

    Newman-Toker, David E; Kerber, Kevin A; Hsieh, Yu-Hsiang; Pula, John H; Omron, Rodney; Saber Tehrani, Ali S; Mantokoudis, Georgios; Hanley, Daniel F; Zee, David S; Kattah, Jorge C

    2013-10-01

    Dizziness and vertigo account for about 4 million emergency department (ED) visits annually in the United States, and some 160,000 to 240,000 (4% to 6%) have cerebrovascular causes. Stroke diagnosis in ED patients with vertigo/dizziness is challenging because the majority have no obvious focal neurologic signs at initial presentation. The authors sought to compare the accuracy of two previously published approaches purported to be useful in bedside screening for possible stroke in dizziness: a clinical decision rule (head impulse, nystagmus type, test of skew [HINTS]) and a risk stratification rule (age, blood pressure, clinical features, duration of symptoms, diabetes [ABCD2]). This was a cross-sectional study of high-risk patients (more than one stroke risk factor) with acute vestibular syndrome (AVS; acute, persistent vertigo or dizziness with nystagmus, plus nausea or vomiting, head motion intolerance, and new gait unsteadiness) at a single academic center. All underwent neurootologic examination, neuroimaging (97.4% by magnetic resonance imaging [MRI]), and follow-up. ABCD2 risk scores (0-7 points), using the recommended cutoff of ≥4 for stroke, were compared to a three-component eye movement battery (HINTS). Sensitivity, specificity, and positive and negative likelihood ratios (LR+, LR-) were assessed for stroke and other central causes, and the results were stratified by age. False-negative initial neuroimaging was also assessed. A total of 190 adult AVS patients were assessed (1999-2012). Median age was 60.5 years (range = 18 to 92 years; interquartile range [IQR] = 52.0 to 70.0 years); 60.5% were men. Final diagnoses were vestibular neuritis (34.7%), posterior fossa stroke (59.5% [105 infarctions, eight hemorrhages]), and other central causes (5.8%). Median ABCD2 was 4.0 (range = 2 to 7; IQR = 3.0 to 4.0). ABCD2 ≥ 4 for stroke had sensitivity of 61.1%, specificity of 62.3%, LR+ of 1.62, and LR- of 0.62; sensitivity was lower for those

  17. Higgs hints

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1991-10-15

    As well as dominating the news at the recent Joint International Lepton-Photon Symposium and Europhysics Conference on High Energy Physics in Geneva, results from the four big experiments - Aleph , Delphi, L3 and Opal - at CERN's big LEP electron-positron collider had far-reaching implications.

  18. Employing UMLS for generating hints in a tutoring system for medical problem-based learning.

    Science.gov (United States)

    Kazi, Hameedullah; Haddawy, Peter; Suebnukarn, Siriwan

    2012-06-01

    While problem-based learning has become widely popular for imparting clinical reasoning skills, the dynamics of medical PBL require close attention to a small group of students, placing a burden on medical faculty, whose time is over taxed. Intelligent tutoring systems (ITSs) offer an attractive means to increase the amount of facilitated PBL training the students receive. But typical intelligent tutoring system architectures make use of a domain model that provides a limited set of approved solutions to problems presented to students. Student solutions that do not match the approved ones, but are otherwise partially correct, receive little acknowledgement as feedback, stifling broader reasoning. Allowing students to creatively explore the space of possible solutions is exactly one of the attractive features of PBL. This paper provides an alternative to the traditional ITS architecture by using a hint generation strategy that leverages a domain ontology to provide effective feedback. The concept hierarchy and co-occurrence between concepts in the domain ontology are drawn upon to ascertain partial correctness of a solution and guide student reasoning towards a correct solution. We describe the strategy incorporated in METEOR, a tutoring system for medical PBL, wherein the widely available UMLS is deployed and represented as the domain ontology. Evaluation of expert agreement with system generated hints on a 5-point likert scale resulted in an average score of 4.44 (Spearman's ρ=0.80, p<0.01). Hints containing partial correctness feedback scored significantly higher than those without it (Mann Whitney, p<0.001). Hints produced by a human expert received an average score of 4.2 (Spearman's ρ=0.80, p<0.01). Copyright © 2012 Elsevier Inc. All rights reserved.

  19. The Diagnostic Accuracy of Truncal Ataxia and HINTS as Cardinal Signs for Acute Vestibular Syndrome

    Directory of Open Access Journals (Sweden)

    Sergio Carmona

    2016-08-01

    Full Text Available The head impulse, nystagmus type, test of skew (HINTS protocol set a new paradigm to differentiate peripheral vestibular disease from stroke in patients with acute vestibular syndrome (AVS. The relationship between degree of truncal ataxia and stroke has not been systematically studied in patients with AVS. We studied a group of 114 patients who were admitted to a General Hospital due to AVS, 72 of them with vestibular neuritis (based on positive head impulse, abnormal caloric tests and negative MRI, and the rest with Stroke: 32 in the PICA territory (positive HINTS findings, positive MRI and 10 in the AICA territory (variable findings and grade 3 Ataxia, positive MRI. Truncal ataxia was measured by independent observers as grade 1, mild to moderate imbalance with walking independently; grade 2, severe imbalance with standing, but cannot walk without support; and grade 3, falling at upright posture.When we applied the HINTS protocol to our sample, we obtained 100% sensitivity and 94.4% specificity, similar to previously published findings. Only those patients with stroke presented with grade 3 ataxia. Of those with grade 2 ataxia (n = 38, 11 had cerebellar stroke and 28 had vestibular neuritis, not related to the patient's age. Grade 2-3 ataxia was 92.9% sensitive and 61.1% specific to detect AICA/PICA stroke in patients with AVS, with 100% sensitivity to detect AICA stroke. In turn, two signs (nystagmus of central origin and grade 2-3 Ataxia had 100% sensitivity and 61.1% specificity. Ataxia is less sensitive than HINTS but much easier to evaluate.

  20. Anti-depressant and anxiolytic like behaviors in PKCI/HINT1 knockout mice associated with elevated plasma corticosterone level

    Directory of Open Access Journals (Sweden)

    Wang Jia

    2009-11-01

    Full Text Available Abstract Background Protein kinase C interacting protein (PKCI/HINT1 is a small protein belonging to the histidine triad (HIT family proteins. Its brain immunoreactivity is located in neurons and neuronal processes. PKCI/HINT1 gene knockout (KO mice display hyper-locomotion in response to D-amphetamine which is considered a positive symptom of schizophrenia in animal models. Postmortem studies identified PKCI/HINT1 as a candidate molecule for schizophrenia and bipolar disorder. We investigated the hypothesis that the PKCI/HINT1 gene may play an important role in regulating mood function in the CNS. We submitted PKCI/HINT1 KO mice and their wild type (WT littermates to behavioral tests used to study anti-depressant, anxiety like behaviors, and goal-oriented behavior. Additionally, as many mood disorders coincide with modifications of hypothalamic-pituitary-adrenal (HPA axis function, we assessed the HPA activity through measurement of plasma corticosterone levels. Results Compared to the WT controls, KO mice exhibited less immobility in the forced swim (FST and the tail suspension (TST tests. Activity in the TST tended to be attenuated by acute treatment with valproate at 300 mg/kg in KO mice. The PKCI/HINT1 KO mice presented less thigmotaxis in the Morris water maze and spent progressively more time in the lit compartment in the light/dark test. In a place navigation task, KO mice exhibited enhanced acquisition and retention. Furthermore, the afternoon basal plasma corticosterone level in PKCI/HINT1 KO mice was significantly higher than in the WT. Conclusion PKCI/HINT1 KO mice displayed a phenotype of behavioral and endocrine features which indicate changes of mood function, including anxiolytic-like and anti-depressant like behaviors, in conjunction with an elevated corticosterone level in plasma. These results suggest that the PKCI/HINT 1 gene could be important for the mood regulation function in the CNS.

  1. Axion-like particles: possible hints and constraints from the high-energy Universe

    International Nuclear Information System (INIS)

    Brun, Pierre

    2013-01-01

    The high-energy Universe is potentially a great laboratory for searching new light bosons such as axion-like particles (ALPs). Cosmic sources are indeed the scene of violent phenomena that involve strong magnetic field and/or very long baselines, where the effects of the mixing of photons with ALPs could lead to observable effects. Two examples are archetypal of this fact, that are the Universe opacity to gamma-rays and the imprints of astrophysical magnetic turbulence in the energy spectra of high-energy sources. In the first case, hints for the existence of ALPs can be proposed whereas the second one is used to put constraints on the ALP mass and coupling to photons

  2. Hint of nonstandard Mikheyev-Smirnov-Wolfenstein dynamics in solar neutrino conversion

    International Nuclear Information System (INIS)

    Palazzo, Antonio

    2011-01-01

    Motivated by the recent low-threshold measurements of the solar 8 B neutrino spectrum performed by Borexino, Super-Kamiokande and the Sudbury Neutrino Observatory--all now monitoring the transition regime between low-energy (vacuumlike) and high-energy (matter-dominated) flavor conversions--we consider the role of subdominant dynamical terms induced by new flavor-changing interactions. We find that the presence of such perturbations with strength ∼10 -1 G F is now favored, offering a better description of the anomalous behavior suggested by the new results, whose spectrum shows no sign of the typical low-energy upturn predicted by the standard Mikheyev-Smirnov-Wolfenstein (MSW) mechanism. Our findings, if interpreted in a 2-flavor scheme, provide a hint of such new interactions at the ∼2σ level, which is rather robust with respect to 3-flavor effects possibly induced by nonzero θ 13 .

  3. Hint of nonstandard Mikheyev-Smirnov-Wolfenstein dynamics in solar neutrino conversion

    Science.gov (United States)

    Palazzo, Antonio

    2011-05-01

    Motivated by the recent low-threshold measurements of the solar B8 neutrino spectrum performed by Borexino, Super-Kamiokande and the Sudbury Neutrino Observatory—all now monitoring the transition regime between low-energy (vacuumlike) and high-energy (matter-dominated) flavor conversions—we consider the role of subdominant dynamical terms induced by new flavor-changing interactions. We find that the presence of such perturbations with strength ˜10-1GF is now favored, offering a better description of the anomalous behavior suggested by the new results, whose spectrum shows no sign of the typical low-energy upturn predicted by the standard Mikheyev-Smirnov-Wolfenstein (MSW) mechanism. Our findings, if interpreted in a 2-flavor scheme, provide a hint of such new interactions at the ˜2σ level, which is rather robust with respect to 3-flavor effects possibly induced by nonzero θ13.

  4. Hints for clarification of influencing factors in case of occupational liver diseases

    Energy Technology Data Exchange (ETDEWEB)

    Zober, A; Raithel, H; Valentin, H

    1981-05-01

    Clarification of influencing factors is of great importance in suspected occupational liver diseases. Hints are given on the basis of the author's own experience and after critical evaluation of the relevant literature. Most important are: 1) Establishment of a comprehensive working anamnesis with special regard to specific features of the job, exposure patterns, and all working materials; 2) assessment of the hepatotoxic potential of the suspected working material according to the present state of knowledge in working medicine and toxicology; 3) objectification and quantification of the suspected noxious substances at the place of work by means of air analysis and analysis of the biological matter; 4) differential diagnosis in view of possible competitive influencing factors.

  5. Hint of a Z' boson from the CERN LEP II data

    International Nuclear Information System (INIS)

    Gulov, A. V.; Skalozub, V. V.

    2007-01-01

    The many-parametric fits of the LEP2 data on e + e - →e + e - , μ + μ - , τ + τ - processes are performed with the goal to estimate the signals of the Abelian Z ' boson. Four independent parameters must be fitted, if the derived already low-energy relations between the Z ' couplings to the standard model fermions are taken into consideration. No signals are found when the complete LEP2 data set for these processes is treated. In the fit of the backward bins, the hint at the 1.3σ confidence level is detected. The Z ' couplings to the vector and axial-vector lepton currents are constrained. The comparisons with the one-parameter fits and with the corresponding LEP1 experiments are fulfilled

  6. Modelling magnetic islands in the H-1NF heliac with the hint code

    International Nuclear Information System (INIS)

    Lloyd, S.S.; Gardner, H.J.

    1999-01-01

    Full text: Recent progress in the theoretical modelling of the effects of plasma pressure on the growth and change in geometry of magnetic islands in the H-1NF Heliac will be reviewed. The HINT magnetohydrodynamic equilibrium code, which has become a standard workhorse in the stellarator community for problems of this type, has been modified to incorporate an interpolation algorithm which significantly accelerates its convergence. This has enabled the critical evaluation of earlier results, and of some conventional wisdom. In many ways the treatment of magnetic islands in low shear fusion reactors, such as H-1NF, is an ideal case study in computational science - the devil is in the details and the devil is important: the existence or otherwise of island self-healing at reactor pressures could significantly affect the design of future experiments. (author)

  7. Altered Light Conditions Contribute to Abnormalities in Emotion and Cognition Through HINT1 Dysfunction in C57BL/6 Mice

    Directory of Open Access Journals (Sweden)

    Yuan Zhou

    2018-06-01

    Full Text Available In recent years, the environmental impact of artificial light at night has been a rapidly growing global problem, affecting 99% of the population in the US and Europe, and 62% of the world population. The present study utilized a mouse model exposed to long-term artificial light and light deprivation to explore the impact of these conditions on emotion and cognition. Based on the potential links between histidine triad nucleotide binding protein 1 (HINT1 and mood disorders, we also examined the expression of HINT1 and related apoptosis factors in the suprachiasmatic nucleus (SCN, prefrontal cortex (PFC, nucleus accumbens (NAc and hippocampus (Hip. Mice exposed to constant light (CL exhibited depressive- and anxiety-like behaviors, as well as impaired spatial memory, as demonstrated by an increased immobility time in the tail suspension and forced swimming tests, less entries and time spent in the open arms of elevated plus-maze, and less platform site crossings and time spent in the target quadrant in the Morris water maze (MWM. The effects of constant darkness (CD partially coincided with long-term illumination, except that mice in the CD group failed to show anxiety-like behaviors. Furthermore, HINT1 was upregulated in four encephalic regions, indicating that HINT1 may be involved in mood disorders and cognitive impairments due to altered light exposure. The apoptosis-related proteins, BAX and BCL-2, showed the opposite expression pattern, reflecting an activated apoptotic pathway. These findings suggest that exposure to CL and/or darkness can induce significant changes in affective and cognitive responses, possibly through HINT1-induced activation of apoptotic pathways.

  8. Seven Hints for Primordial Black Hole Dark Matter arXiv

    CERN Document Server

    Clesse, Sebastien

    Seven observations point towards the existence of primordial black holes (PBH), constituting the whole or an important fraction of the dark matter in the Universe: the mass and spin of black holes detected by Advanced LIGO/VIRGO, the detection of micro-lensing events of distant quasars and stars in M31, the non-detection of ultra-faint dwarf satellite galaxies with radius below 15 parsecs, evidences for core galactic dark matter profiles, the correlation between X-ray and infrared cosmic backgrounds, and the existence of super-massive black holes very early in the Universe's history. Some of these hints are newly identified and they are all intriguingly compatible with the re-constructed broad PBH mass distribution from LIGO events, peaking on PBH mass $m_{\\rm PBH} \\approx 3 M_\\odot$ and passing all other constraints on PBH abundances. PBH dark matter also provides a new mechanism to explain the mass-to-light ratios of dwarf galaxies, including the recent detection of a diffuse galaxy not dominated by dark ma...

  9. HEALTH INFO SANTÉ – REMINDER ANNUAL DEDUCTIBLE AND REIMBURSEMENT CLAIMS HINTS FOR USE

    CERN Multimedia

    CHIS Board

    2000-01-01

    Information from the CHIS Board and the Human Resources Division:Annual deductible and reimbursement claims: hints for useOne should bear in mind that the annual deductible is an amount (currently CHF 100) charged automatically by the Administrator of the scheme for every adult aged 18 and above. This is what happens: The amount is deducted annually for all medical services received over a calendar year.It is triggered by the date of the treatment and neither by the date of the bill nor that of the reimbursement claim.In other words, if you receive medical treatment in December for the first time in a given year, the CHF 100 will be deducted from the claim for that treatment. So, except for urgent cases, it would be better to wait till the following month, thus avoiding one annual deductible.It is also worth remembering that the cost of processing our reimbursement claims - and there were 54, 000 in 1999 - is part of the cost of our insurance.Help keep administrative costs down: do not submit reimbursement cl...

  10. Development and Validation of a Novel Generic Health-related Quality of Life Instrument With 20 Items (HINT-20

    Directory of Open Access Journals (Sweden)

    Min-Woo Jo

    2017-01-01

    Full Text Available Objectives Few attempts have been made to develop a generic health-related quality of life (HRQoL instrument and to examine its validity and reliability in Korea. We aimed to do this in our present study. Methods After a literature review of existing generic HRQoL instruments, a focus group discussion, in-depth interviews, and expert consultations, we selected 30 tentative items for a new HRQoL measure. These items were evaluated by assessing their ceiling effects, difficulty, and redundancy in the first survey. To validate the HRQoL instrument that was developed, known-groups validity and convergent/discriminant validity were evaluated and its test-retest reliability was examined in the second survey. Results Of the 30 items originally assessed for the HRQoL instrument, four were excluded due to high ceiling effects and six were removed due to redundancy. We ultimately developed a HRQoL instrument with a reduced number of 20 items, known as the Health-related Quality of Life Instrument with 20 items (HINT-20, incorporating physical, mental, social, and positive health dimensions. The results of the HINT-20 for known-groups validity were poorer in women, the elderly, and those with a low income. For convergent/discriminant validity, the correlation coefficients of items (except vitality in the physical health dimension with the physical component summary of the Short Form 36 version 2 (SF-36v2 were generally higher than the correlations of those items with the mental component summary of the SF-36v2, and vice versa. Regarding test-retest reliability, the intraclass correlation coefficient of the total HINT-20 score was 0.813 (p<0.001. Conclusions A novel generic HRQoL instrument, the HINT-20, was developed for the Korean general population and showed acceptable validity and reliability.

  11. Legal issues concerning local governments / Vallo Olle

    Index Scriptorium Estoniae

    Olle, Vallo, 1966-

    1997-01-01

    Valla/linna põhimääruse õiguslikust regulatsioonist, kohaliku omavalitsuse korralduse seadusest, äriseadustikust, munitsipaalettevõtete ümberkujundamisest ja nende õigusaktide väljunditest Tartu linna põhimääruses ning teistes Tartus tehtud õiguslikes otsustustes

  12. Auto Euroopa Liidus kallim / Sulev Oll

    Index Scriptorium Estoniae

    Oll, Sulev, 1964-

    2001-01-01

    Euroopa Liiduga liitumisel tuleb uue auto eest välja käia vähemalt 10 000 krooni rohkem, kuna plaanide kohaselt ei tohi liikmesriikides autode hinnaerinevused ületada 12%. Ilmunud ka: Delovõje Vedomosti, 28. märts 2001, lk. 7

  13. Milline on ilus maja? / Sulev Oll

    Index Scriptorium Estoniae

    Oll, Sulev, 1964-

    2008-01-01

    Ilusatest majadest ja arhitektuurikonkursside võiduprojektidest. Konkursist "Brick Award". Tallinna sünagoog valiti rahvusvahelise tellisarhitektuuri aastaraamatusse "brick'08" (arhitektid Lembit-Kaur Stöör, Andrus Kõresaar, Tõnis Kimmel arhitektuuribüroost KOKO Arhitektid). Loetletud konkursi "Aasta betoonehitis" võitjad läbi aegade. Kommenteerivad Margit Mutso, Emil Urbel

  14. Hint from the interfamily mass hierarchy: Two vectorlike families in the TeV range

    Science.gov (United States)

    Babu, K. S.; Pati, Jogesh C.; Stremnitzer, Hanns

    1995-03-01

    Two vectorlike familes QL,R=(U, D, N, E)L,R and Q'L,R=(U', D', N', E')L,R with masses of order 1 TeV, one of which is a doublet of SU(2)L and the other a doublet of SU(2)R, have been predicted to exist, together with the three observed chiral families, in the context of a viable and economical SUSY preon model. The model itself possesses many attractive features which include explanations of the origins of (i) diverse mass scales, (ii) family replication, (iii) protection of the masses of the composite quarks and leptons compared to their compositeness scales, and (iv) interfamily mass hierarchy. The existence of the two vectorlike familes, a prediction of the model, turns out to be crucial especially for an explanation of the interfamily mass hierarchy (IFMH). Given the simplicity of the explanation, the observed IFMH in turn appears to us to be a strong hint in favor of the existence of the two vectorlike families. This paper is devoted to a detailed study of the expected masses, mixings and decay modes of the fermions belonging to the two vectorlike families, in the context of the SUSY preon model, with the inclusion of the renormalization effects due to the standard model gauge interactions. Including QCQ renormalization effects, the masses of the vectorlike quarks are expected to lie in the range of 500 GeV to about 2.5 TeV, while those of the vectorlike leptons are expected to be in the range of 200 GeV to 1 TeV. Their mass pattern and decay modes exhibit certain distinguishing features and characteristic signals. For example, when the CERN LHC and, possibly a future version of the SSC are built, pair production of the vectorlike quarks would lead to systems such as (bb¯+4Z+W+W-) and (bb¯+2Z+W+W-), while an e-e+ linear collider (NLC) of suitable energy can produce appreciably a single neutral heavy lepton N together, with ντ, followed by the decay of N into (Z+ντ)-->(e-e+)+ντ. This last signal may conceivably materialize even at CERN LEP 200 if N is

  15. Smartphone Ownership Among US Adult Cigarette Smokers: 2014 Health Information National Trends Survey (HINTS) Data.

    Science.gov (United States)

    Heffner, Jaimee L; Mull, Kristin E

    2017-08-31

    Despite increasing interest in smartphone apps as a platform for delivery of tobacco cessation interventions, no previous studies have evaluated the prevalence and characteristics of smokers who can access smartphone-delivered interventions. To guide treatment development in this new platform and to evaluate disparities in access to smartphone-delivered interventions, we examined associations of smartphone ownership with demographics, tobacco use and thoughts about quitting, other health behaviors, physical and mental health, health care access, and Internet and technology utilization using a nationally representative sample of US adult smokers. Data were from the National Cancer Institute's 2014 Health Information National Trends Survey 4 (HINTS 4), Cycle 4. This mailed survey targeted noninstitutionalized individuals aged 18 years or older using two-stage stratified random sampling. For this analysis, we restricted the sample to current smokers with complete data on smartphone ownership (n=479). Nearly two-thirds (weighted percent=63.8%, 248/479) of smokers reported owning a smartphone. Those who were younger (P<.001), employed (P=.002), never married (P=.002), and had higher education (P=.002) and income (P<.001) had the highest rates of ownership. Smartphone owners did not differ from nonowners on frequency of smoking, recent quit attempts, or future plans to quit smoking, although they reported greater belief in the benefits of quitting (P=.04). Despite being equally likely to be overweight or obese, smartphone owners reported greater fruit and vegetable consumption (P=.03) and were more likely to report past-year efforts to increase exercise (P=.001) and to lose weight (P=.02). No differences in health care access and utilization were found. Smartphone owners reported better physical and mental health in several domains and higher access to and utilization of technology and the Internet, including for health reasons. Smartphone ownership among smokers mirrors

  16. PsHint1, associated with the G-protein α subunit PsGPA1, is required for the chemotaxis and pathogenicity of Phytophthora sojae.

    Science.gov (United States)

    Zhang, Xin; Zhai, Chunhua; Hua, Chenlei; Qiu, Min; Hao, Yujuan; Nie, Pingping; Ye, Wenwu; Wang, Yuanchao

    2016-02-01

    Zoospore chemotaxis to soybean isoflavones is essential in the early stages of infection by the oomycete pathogen Phytophthora sojae. Previously, we have identified a G-protein α subunit encoded by PsGPA1 which regulates the chemotaxis and pathogenicity of P. sojae. In the present study, we used affinity purification to identify PsGPA1-interacting proteins, including PsHint1, a histidine triad (HIT) domain-containing protein orthologous to human HIT nucleotide-binding protein 1 (HINT1). PsHint1 interacted with both the guanosine triphosphate (GTP)- and guanosine diphosphate (GDP)-bound forms of PsGPA1. An analysis of the gene-silenced transformants revealed that PsHint1 was involved in the chemotropic response of zoospores to the isoflavone daidzein. During interaction with a susceptible soybean cultivar, PsHint1-silenced transformants displayed significantly reduced infectious hyphal extension and caused a strong cell death in plants. In addition, the transformants displayed defective cyst germination, forming abnormal germ tubes that were highly branched and exhibited apical swelling. These results suggest that PsHint1 not only regulates chemotaxis by interacting with PsGPA1, but also participates in a Gα-independent pathway involved in the pathogenicity of P. sojae. © 2015 BSPP AND JOHN WILEY & SONS LTD.

  17. Effects of yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 on the IgA flow rate of saliva in elderly persons residing in a nursing home: A before-after non-randomised intervention study.

    Science.gov (United States)

    Yamamoto, Yuko; Fujino, Kazuhiro; Saruta, Juri; Takahashi, Toru; To, Masahiro; Fuchida, Shinya; Shimizu, Tomoko; Kamata, Yohei; Misawa, Kyoko; Tsukinoki, Keiichi

    2017-12-01

    The aim of this study was to investigate the alterations in the salivary IgA levels of elderly persons administered yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus (L. bulgaricus) OLL1073R-1, which has been reported to reduce the risk of colds. Salivary immunoglobulin (Ig)A plays an important role in the defence of the oral cavity mucous membrane against foreign antigens and pathogens. Accordingly, low levels of salivary IgA are associated with an increased risk of upper respiratory tract infection. Furthermore, salivary IgA secretion has been reported to decrease with age. Recently, several studies have reported that certain strains of Lactobacillus and their products can modulate the immune response, but there are currently few studies on the effects of on the IgA level in human saliva. This was a before-after non-randomised intervention study. Thirty-seven elderly persons (mean age, 82.7 years) residing in a single nursing home ingested 112 g of the yogurt every morning for 12 weeks. The participants' saliva was collected before and after 4, 8 and 12 weeks of yogurt intake. Our results showed that yogurt intake affected the concentration of IgA in the saliva (P < .0001). Additionally, yogurt intake and the body weight of the participants affected the IgA flow rate of saliva (P = .0003 and .03, respectively). Continuous intake of yogurt fermented with L. bulgaricus OLL1073R-1 may help improve the mucosal immune function in elderly people with weakened immune systems. © 2017 John Wiley & Sons A/S and The Gerodontology Association. Published by John Wiley & Sons Ltd.

  18. Nad kem smejomsja? Da nad soboi! A zrja / Dimitri Klenski

    Index Scriptorium Estoniae

    Klenski, Dimitri, 1945-

    2007-01-01

    Autor kritiseerib ajakirjanik Marianna Tarassenko mõtteid, kes peale parlamendivalimisi analüüsis vene parteide ebaedu ja leidis, et selliseid rahvuse järgi moodustatud erakondi ei ole vaja. Autor analüüsib venekeelse elanikkonna olukorda riigis ja süüdistab vene intelligentsi, ajakirjanikke ja ärimehi ükskõiksuses vene kogukonna probleemidesse suhtumisel

  19. Letter to Dimitrie Gusti (21.10.1938

    Directory of Open Access Journals (Sweden)

    ŞTEFANIA CRISTESCU

    2013-07-01

    Full Text Available This section contains two important documents here published for the first time. The first is the text of a paper presented by St.C.-G. in 1939 at the Romanian Institute for Social Research and meant to accompany 12 sociological maps on the practices and interdictions concerning confined women in 35 villages of Țara Oltului (Olt county. This paper will allow us to reconstruct the lost maps in the near future. The second document consists of three completed forms of the social inquiry conducted by Șt. C.-G. concerning the everyday lives of students in an industrial College of Bucharest during World War II. The Report prepared by D. Gusti in view of awarding the Vernescu Academy prize to Șt. C.-G. for her book The Household in the Beliefs and Magic Rituals of the Women of Drăguș (Făgăraș, an activity report by Șt. C. and two letters (one by D. Gusti and the other by a former student teaching in her turn complete the picture of Șt. C.-G. at a professional and a personal level.

  20. Health Information National Trends Survey in American Sign Language (HINTS-ASL): Protocol for the Cultural Adaptation and Linguistic Validation of a National Survey.

    Science.gov (United States)

    Kushalnagar, Poorna; Harris, Raychelle; Paludneviciene, Raylene; Hoglind, TraciAnn

    2017-09-13

    The Health Information National Trends Survey (HINTS) collects nationally representative data about the American's public use of health-related information. This survey is available in English and Spanish, but not in American Sign Language (ASL). Thus, the exclusion of ASL users from these national health information survey studies has led to a significant gap in knowledge of Internet usage for health information access in this underserved and understudied population. The objectives of this study are (1) to culturally adapt and linguistically translate the HINTS items to ASL (HINTS-ASL); and (2) to gather information about deaf people's health information seeking behaviors across technology-mediated platforms. We modified the standard procedures developed at the US National Center for Health Statistics Cognitive Survey Laboratory to culturally adapt and translate HINTS items to ASL. Cognitive interviews were conducted to assess clarity and delivery of these HINTS-ASL items. Final ASL video items were uploaded to a protected online survey website. The HINTS-ASL online survey has been administered to over 1350 deaf adults (ages 18 to 90 and up) who use ASL. Data collection is ongoing and includes deaf adult signers across the United States. Some items from HINTS item bank required cultural adaptation for use with deaf people who use accessible services or technology. A separate item bank for deaf-related experiences was created, reflecting deaf-specific technology such as sharing health-related ASL videos through social network sites and using video remote interpreting services in health settings. After data collection is complete, we will conduct a series of analyses on deaf people's health information seeking behaviors across technology-mediated platforms. HINTS-ASL is an accessible health information national trends survey, which includes a culturally appropriate set of items that are relevant to the experiences of deaf people who use ASL. The final HINTS

  1. ALGUNAS PAUTAS PARA LA ESCRITURA DE ARTÍCULOS CIENTÍFICOS SOME HINTS FOR WRITING SCIENTIFIC PAPERS

    Directory of Open Access Journals (Sweden)

    Carlos M Zapata

    2008-06-01

    Full Text Available El objetivo de este artículo es presentar, a aquellos investigadores neófitos, una serie de pautas que faciliten los procesos de escritura y publicación de manuscritos en revistas científicas de corriente principal. En la comunidad científica, una investigación sólo se completa cuando los resultados se socializan a través de artículos en revistas arbitradas que garanticen la originalidad, importancia y validez científica de los hallazgos reportados. Consecuentemente, es necesario que los investigadores desarrollen destrezas y habilidades en la escritura científica. Sin embargo, el proceso de preparación de un manuscrito, desde su fase inicial hasta su publicación final, suele ser largo y difícil, debido a algunos factores clave que tienen influencia sobre su calidad. Este artículo, suministra lineamientos generales sobre la preparación de manuscritos y entrega, también, pautas alrededor de las buenas prácticas de escritura de artículos con miras a facilitar la revisión por parte de los árbitros. En este sentido, este trabajo constituye aporte para quienes se inician en la difusión de la investigación científica.The objective of this paper is to present, to those neophyte researchers, a set of hints that facilitate manuscript writing and publishing processes needed for high class scientific journals. In the scientific community, a research would only be completed when the results are shared through papers in peer-reviewed journals that guarantees the originality, importance and scientific validation of reported contributions. Consequently, researchers have the necessity to develop skills and abilities in scientific writing. However, the manuscript preparation process from the initial phase to the final publication is usually slow and difficult, due to some key factors having influence over its quality. In this paper, we present general guidelines about manuscript preparation and we give some hints about good scientific

  2. W7-X vacuum and finite-β magnetic field structure resolved with the HINT 3D equilibrium code

    International Nuclear Information System (INIS)

    Hayashi, T.; Merkel, P.; Nuehrenberg, J.; Schwenn, U.

    1994-01-01

    The 3D equilibrium code HINT allows the direct investigation of finite-β effects on sizes and phases of islands in genuinely 3D configurations like the W7-X stellarator planned by the Max-Planck-Institut fuer Plasmaphysik in Germany. The code does not require the existence of nested flux surfaces. This, in contrast to the inverse formulation used in the VMEC code, leads to a considerably more complex computational goal. The HINT code combines some crucial features reducing the numerical problems and the computational effort to such an extent as to allow computation of 3D equilibria at finite-β with magnetic islands. The code is based on a two-step procedure: Starting from a given B and an initial pressure, the iteration technique for the pressure advancement is differencing in an artificial time with an explicit 4th order scheme, or - alternatively for resolving the island topology - field lines starting from all gridpoints are followed long enough to allow pressure equalization along these. B.∇p 0, for fixed B. In a second step, p is kept fixed and B is advanced with an artificial time for solving ∇p - jxB = 0 under the constraint of vanishing toroidal current J. The differential equations are discretized in space with 4th order difference approximations on an Eulerian grid spanned by a rectangular box whose toroidal rotation law follows the W7-X geometry. The two sub-iteration steps are repeated until the force balance is satisfied to an appropriate accuracy. The boundaries (where the boundary conditions are prescribed) are far enough away from the last closed magnetic surface, thus guaranteeing the motion of the plasma column not being constrained by the boundary conditions. Due to the stellarator symmetry in the toroidal direction only half of an equilibrium period is computed, using modified periodic boundary conditions guaranteeing the 4th order of the spatial discretization. (author) 5 refs., 4 figs

  3. Eesti Vabariigi põhiseadus : kommenteeritud väljaanne / toimetuskolleegium: Eerik-Juhan Truuväli, Berit Aaviksoo, Oliver Kask, Lasse Lehis, Lauri Madise, Ülle Madise, Kalle Merusk, Lauri Mälksoo, Raul Narits, Vallo Olle, Peep Pruks

    Index Scriptorium Estoniae

    2008-01-01

    Kommentaaride autorid ja sisu: Sissejuhatus / Raul Narits, Lauri Madise, Heinrich Schneider. Preambul / Raul Narits, Heinrich Schneider. I ptk. / Kalle Merusk, Taavi Annus, Madis Ernits, Heiki Lindpere, Lauri Madise. II ptk. / Oliver Kask, Madis Ernits, Taavi Annus, Peeter Roosma, Rait Maruste, Eerik Kergandberg, Ivo Pilving, Uno Lõhmus, Merilin Kiviorg, Einar Vene, Ülle Madise. III ptk. / Oliver Kask. IV ptk. / Lauri Madise, Aaro Mõttus, Jüri Põld, Tiina Runthal. V ptk. / Eerik-Juhan Truuväli, Ülle Madise, Jüri Põld, Urmas Reinsalu. VI ptk. / Kalle Merusk, Jüri Põld. VII ptk. / Eerik-Juhan Truuväli, Jüri Liventaal, Jüri Põld. VIII ptk. / Lasse Lehis. IX ptk. / Kristi Land, Heiki Lindpere, Lauri Madise, Heiki Pisuke. X ptk. / Oliver Kask, Enn Markvart, Jüri Põld. XI ptk. / Ülle Madise, Janek Laidvee, Heinrich Schneider. XII ptk. / Berit Aaviksoo, Mihkel Allik, Enn Markvart, Raul Narits, Aare Reenumägi, Peeter Roosma. XIII ptk. / Raul Narits, Uno Lõhmus, Madis Ernits, Jüri Põld. XIV ptk. / Vallo Olle, Arno Almann, Jüri Liventaal, Ülle Madise. XV ptk. / Eerik-Juhan Truuväli, Aaro Mõttus. Eesti Vabariigi põhiseaduse rakendamise seadus / Oliver Kask, Raul Narits, Peeter Roosma. Eesti Vabariigi põhiseaduse täiendamise seadus / Berit Aaviksoo, Julia Laffranque, Ülle Madise, Jüri Põld. Eesti Vabariigi põhiseadus 1990-2008 : bibliograafia (seisuga september 2008) / koost. Maia Ruttu

  4. Eesti Vabariigi põhiseadus : kommenteeritud väljaanne / toimetuskolleegium: Eerik-Juhan Truuväli, Oliver Kask, Lasse Lehis, Heiki Lindpere, Uno Lõhmus, Ülle Madise, Kalle Merusk, Raul Narits, Vallo Olle, Jüri Põld, Heinrich Schneider

    Index Scriptorium Estoniae

    2002-01-01

    Kommentaaride autorid ja sisu: Sissejuhatus / Raul Narits, Heinrich Schneider, Lauri Madise. [Preambul] / Heinrich Schneider. I ptk. / Kalle Merusk, Taavi Annus, Madis Ernits, Heiki Lindpere, Lauri Madise. II ptk. / Uno Lõhmus, Taavi Annus, Madis Ernits, Oliver Kask, Eerik Kergandberg, Rait Maruste, Peeter Roosma. III ptk. / Oliver Kask. IV ptk. / Jüri Põld, Lauri Madise, Aaro Mõttus. V ptk. / Eerik-Juhan Truuväli, Ülle Madise, Jüri Põld, Urmas Reinsalu. VI ptk. / Kalle Merusk, Jüri Põld. VII ptk. / Eerik-Juhan Truuväli, Jüri Põld. VIII ptk. / Lasse Lehis. IX ptk. / Heiki Lindpere, Kristi Land, Lauri Madise, Heiki Pisuke. X ptk. / Oliver Kask, Enn Markvart, Jüri Põld. XI ptk. / Heinrich Schneider. XII ptk. / Raul Narits, Aare Reenumägi, Peeter Roosma, Enn Markvart. XIII ptk. / Uno Lõhmus, Madis Ernits, Jüri Põld. XIV ptk. / Vallo Olle, Arno Almann, Ülle Madise, Jüri Liventaal. XV ptk. / Eerik-Juhan Truuväli, Aaro Mõttus. Eesti Vabariigi põhiseaduse rakendamise seadus / Raul Narits, Peeter Roosma, Oliver Kask. Märksõnastik / koost. Ülle Madise, Peep Pruks. Kasutatud õigusaktide lühendid / koost. Virgo Saarmets. Eesti Vabariigi põhiseadus 1990-2002 : bibliograafia / koost. Maia Ruttu

  5. Patient-provider discussion of online health information: results from the 2007 Health Information National Trends Survey (HINTS).

    Science.gov (United States)

    Chung, Jae Eun

    2013-01-01

    Increasing numbers of people have turned to the Internet for health information. Little has been done beyond speculation to empirically investigate patients' discussion of online health information with health care professionals (HCPs) and patients' perception of HCPs' reactions to such discussion. The author analyzed data from the 2007 Health Information National Trends Survey (HINTS) to identify the characteristics of patients (a) who search for health information on the Internet, (b) who discuss the information found on the Internet with HCPs, and (c) who positively assess HCPs' reaction to the online information. Findings show that men were more likely than were women to have a conversation on online information with HCPs. It is unfortunate that patients who had trouble understanding or trusting online health information were no more likely to ask questions to or seek guidance from HCPs. Reactions of HCPs to online information were perceived as particularly negative by certain groups of patients, such as those who experienced poor health and those who had more concerns about the quality of their searched information. Results are discussed for their implications for patient empowerment and patient-HCP relationships.

  6. Hints for Diagnosis

    DEFF Research Database (Denmark)

    Poulsen, Lars K

    2015-01-01

    /or caretakers. Based on this, a provisional decision to pursue a food allergy diagnosis may be made after carefully considering other possible reasons for an adverse reaction to a food: aversion, infection, intoxication, or an underlying metabolic disease. To respond to the next question, the anamnesis...

  7. Perturbed Lepton-Specific Two-Higgs-Doublet Model Facing Experimental Hints for Physics beyond the Standard Model.

    Science.gov (United States)

    Crivellin, Andreas; Heeck, Julian; Stoffer, Peter

    2016-02-26

    BABAR, Belle, and LHCb Collaborations report evidence for new physics in B→Dτν and B→D^{*}τν of approximately 3.8σ. There is also the long lasting discrepancy of about 3σ in the anomalous magnetic moment of the muon, and the branching ratio for τ→μνν is 1.8σ (2.4σ) above the standard model expectation using the HFAG (PDG) values. Furthermore, CMS Collaboration finds hints for a nonzero decay rate of h→μτ. Interestingly, all these observations can be explained by introducing new scalars. In this Letter we consider these processes within a lepton-specific two-Higgs doublet model (i.e., of type X) with additional nonstandard Yukawa couplings. It is found that one can accommodate τ→μνν with modified Higgs-τ couplings. The anomalous magnetic moment of the muon can be explained if the additional neutral CP-even Higgs boson H is light (below 100 GeV). Also R(D) and R(D^{*}) can be easily explained by additional t-c-Higgs couplings. Combining these t-c couplings with a light H the decay rate for t→Hc can be in a testable range for the LHC. Effects in h→μτ are also possible, but in this case a simultaneous explanation of the anomalous magnetic moment of the muon is difficult due to the unavoidable τ→μγ decay.

  8. The human interactome knowledge base (hint-kb): An integrative human protein interaction database enriched with predicted protein–protein interaction scores using a novel hybrid technique

    KAUST Repository

    Theofilatos, Konstantinos A.

    2013-07-12

    Proteins are the functional components of many cellular processes and the identification of their physical protein–protein interactions (PPIs) is an area of mature academic research. Various databases have been developed containing information about experimentally and computationally detected human PPIs as well as their corresponding annotation data. However, these databases contain many false positive interactions, are partial and only a few of them incorporate data from various sources. To overcome these limitations, we have developed HINT-KB (http://biotools.ceid.upatras.gr/hint-kb/), a knowledge base that integrates data from various sources, provides a user-friendly interface for their retrieval, cal-culatesasetoffeaturesofinterest and computesaconfidence score for every candidate protein interaction. This confidence score is essential for filtering the false positive interactions which are present in existing databases, predicting new protein interactions and measuring the frequency of each true protein interaction. For this reason, a novel machine learning hybrid methodology, called (Evolutionary Kalman Mathematical Modelling—EvoKalMaModel), was used to achieve an accurate and interpretable scoring methodology. The experimental results indicated that the proposed scoring scheme outperforms existing computational methods for the prediction of PPIs.

  9. The relationship between high-frequency pure-tone hearing loss, hearing in noise test (HINT) thresholds, and the articulation index.

    Science.gov (United States)

    Vermiglio, Andrew J; Soli, Sigfrid D; Freed, Daniel J; Fisher, Laurel M

    2012-01-01

    Speech recognition in noise testing has been conducted at least since the 1940s (Dickson et al, 1946). The ability to recognize speech in noise is a distinct function of the auditory system (Plomp, 1978). According to Kochkin (2002), difficulty recognizing speech in noise is the primary complaint of hearing aid users. However, speech recognition in noise testing has not found widespread use in the field of audiology (Mueller, 2003; Strom, 2003; Tannenbaum and Rosenfeld, 1996). The audiogram has been used as the "gold standard" for hearing ability. However, the audiogram is a poor indicator of speech recognition in noise ability. This study investigates the relationship between pure-tone thresholds, the articulation index, and the ability to recognize speech in quiet and in noise. Pure-tone thresholds were measured for audiometric frequencies 250-6000 Hz. Pure-tone threshold groups were created. These included a normal threshold group and slight, mild, severe, and profound high-frequency pure-tone threshold groups. Speech recognition thresholds in quiet and in noise were obtained using the Hearing in Noise Test (HINT) (Nilsson et al, 1994; Vermiglio, 2008). The articulation index was determined by using Pavlovic's method with pure-tone thresholds (Pavlovic, 1989, 1991). Two hundred seventy-eight participants were tested. All participants were native speakers of American English. Sixty-three of the original participants were removed in order to create groups of participants with normal low-frequency pure-tone thresholds and relatively symmetrical high-frequency pure-tone threshold groups. The final set of 215 participants had a mean age of 33 yr with a range of 17-59 yr. Pure-tone threshold data were collected using the Hughson-Weslake procedure. Speech recognition data were collected using a Windows-based HINT software system. Statistical analyses were conducted using descriptive, correlational, and multivariate analysis of covariance (MANCOVA) statistics. The

  10. Estonia : Toward Post-Communist Reconstruction / Aadu Oll

    Index Scriptorium Estoniae

    Oll, Aadu

    2006-01-01

    Pärast Eesti annekteerimist NSV Liidu poolt 1940. a. hävitati Eesti Vabariigi kõik seaduslikud süsteemid ja julgeolekustruktuurid. Eesti territoriaalne NKVD (nõukogude julgeolekuteenistus) rajati järelvalvet teostama Balti riikides. Nõukogude režiimi iseloomustus, KGB ja kommunistliku partei osa Eesti ühiskonnas, KGB ja GRU aktiivsus Eestis ülemineku perioodil, nõukogude süsteemi kokkulangemine, totalitarismist vabanemine

  11. Tsemendirahva kolmekordne pidu / Tapio Aura, Aleksander Nikolajev ; interv. Sulev Oll

    Index Scriptorium Estoniae

    Aura, Tapio

    2005-01-01

    Kunda tsemenditootmisel täitus 135 aastat ja Kunda sadamal 200 aastat. Oma ettevõtete käekäigust räägivad AS-i Kunda Nordic Tsement tegevdirektor Tapio Aura ja Kunda sadama direktor Aleksander Nikolajev

  12. Kolmekihiline Kopli tort Märjamaal / Sulev Oll

    Index Scriptorium Estoniae

    Oll, Sulev, 1964-

    2010-01-01

    Marje Jurtšenko dokumentaalfilmist "Aeg on siin", mis räägib aastast Eesti eri paikades elava nelja 7aastase lapse elus. Filmi esilinastas filmis osalenud Fredile ja tema koolikaaslastele Märjamaa kinos Helk kinomehhaanik Hans Veimann

  13. Eesti meister peresõbralikkuses : Eesti Post / Sulev Oll

    Index Scriptorium Estoniae

    Oll, Sulev, 1964-

    2001-01-01

    Äripäeva ning ajakirja Pere ja Kodu konkursil pälvis Eesti kõige peresõbralikuma firma tiitli Eesti Post. Tabel: 30 peresõbralikumat firmat. Tabel: Eesti Post toetuste jagamisel keskmisest heldem

  14. Hints on cost- and energy saving during lime-sand brick production; Hinweise zur Kosten- und Energieeinsparung bei der Kalksandstein-Produktion

    Energy Technology Data Exchange (ETDEWEB)

    Eden, W.

    2001-05-01

    The publication contains hints for reduction of energy consumption and cost in lime-sand brick production. The information was compiled by Bundesverband Kalksandsteinindustrie e.V. and was derived from technical discussions of the master seminars on production technology of the years 1995 - 2000, consultations form member organizations, or from other sources. [German] Diese Arbeit ist eine Zusammenstellung von Hinweisen zur Reduzierung des Energieverbrauchs und der Kostensenkung bei der KS-Produktion und soll eine Hilfestellung bei entsprechenden Rationalisierungsmassnahmen in den Mitgliedsunternehmen sein. Die hier aufgefuehrten Hinweise und Anregungen entstammen den Fachdiskussionen der Meisterseminare zur Produktionstechnik aus den Jahren 1995 bis 2000, Beratungsgespraechen fuer Mitgliedsunternehmen oder wurden dem Bundesverband Kalksandsteinindustrie eV freundlicherweise fuer die Gemeinschaftsarbeit zur Verfuegung gestellt. (orig.)

  15. Profiling and quantitative evaluation of three Nickel-Coated magnetic matrices for purification of recombinant proteins: lelpful hints for the optimized nanomagnetisable matrix preparation

    Directory of Open Access Journals (Sweden)

    Zarei Saeed

    2011-08-01

    Full Text Available Abstract Background Several materials are available in the market that work on the principle of protein magnetic fishing by their histidine (His tags. Little information is available on their performance and it is often quoted that greatly improved purification of histidine-tagged proteins from crude extracts could be achieved. While some commercial magnetic matrices could be used successfully for purification of several His-tagged proteins, there are some which have been proved to operate just for a few extent of His-tagged proteins. Here, we address quantitative evaluation of three commercially available Nickel nanomagnetic beads for purification of two His-tagged proteins expressed in Escherichia coli and present helpful hints for optimized purification of such proteins and preparation of nanomagnetisable matrices. Results Marked differences in the performance of nanomagnetic matrices, principally on the basis of their specific binding capacity, recovery profile, the amount of imidazole needed for protein elution and the extent of target protein loss and purity were obtained. Based on the aforesaid criteria, one of these materials featured the best purification results (SiMAG/N-NTA/Nickel for both proteins at the concentration of 4 mg/ml, while the other two (SiMAC-Nickel and SiMAG/CS-NTA/Nickel did not work well with respect to specific binding capacity and recovery profile. Conclusions Taken together, functionality of different types of nanomagnetic matrices vary considerably. This variability may not only be dependent upon the structure and surface chemistry of the matrix which in turn determine the affinity of interaction, but, is also influenced to a lesser extent by the physical properties of the protein itself. Although the results of the present study may not be fully applied for all nanomagnetic matrices, but provide a framework which could be used to profiling and quantitative evaluation of other magnetisable matrices and also

  16. AUTOSOMAL RECESSIVE PERIPHERAL NEUROPATHY WITH NEUROMYOTONIA (ARAN-NM: DESCRIPTION OF A CLINICAL CASE CONFIRMED BY A MUTATION IN THE HINT1 GENE

    Directory of Open Access Journals (Sweden)

    Olga A. Klochkova

    2017-01-01

    Full Text Available Autosomal recessive  peripheral neuropathy with neuromyotonia  (ARAN-NM  is a relatively newly described  disease associated  with mutations  in the HINT1 gene.  It accounts  for a significant  part of the poorly  differentiated  forms  of axonal polyneuropathies.  We present the first in Russia description of the genetically confirmed case of ARAN-NM in a boy aged 14 years and 11 months without the hereditary-tainted anamnesis. On presentation,  the patient experienced  progressive  distal muscular weakness, asymmetric foot deformity,  gait disorders  and minimal manifestations  of neuromyotonia  (stiffness  in the fingers.  During examination,  we detected an increase in the level of creatine phosphokinase up to 635 U/l, a disturbance of conduction of motor and, to a lesser extent, sensory fibers  of  the  peripheral  nerves  (according  to  the  stimulation  electromyography,  EMG,  denervation-reinnervation  changes,  single positive acute waves, fibrillation potentials, complex repeated discharge (according to the data of needle EMG. In the study of exome, a homozygous mutation c.110G>C, p.R37P was determined in exon 01 of the HINT1 gene, which confirmed the presence of ARAN-NM. A molecular-genetic  examination of the patient's immediate relatives was carried out. The described case is compared with literature data. An overview of currently available information on ARAN-NM is provided. Diagnostic criteria of the disease are presented.

  17. Nonminimal hints for asymptotic safety

    Science.gov (United States)

    Eichhorn, Astrid; Lippoldt, Stefan; Skrinjar, Vedran

    2018-01-01

    In the asymptotic-safety scenario for gravity, nonzero interactions are present in the ultraviolet. This property should also percolate into the matter sector. Symmetry-based arguments suggest that nonminimal derivative interactions of scalars with curvature tensors should therefore be present in the ultraviolet regime. We perform a nonminimal test of the viability of the asymptotic-safety scenario by working in a truncation of the renormalization group flow, where we discover the existence of an interacting fixed point for a corresponding nonminimal coupling. The back-coupling of such nonminimal interactions could in turn destroy the asymptotically safe fixed point in the gravity sector. As a key finding, we observe nontrivial indications of stability of the fixed-point properties under the impact of nonminimal derivative interactions, further strengthening the case for asymptotic safety in gravity-matter systems.

  18. Dimitrie Gusti and the Royal Cultural Foundations (1922-1948. Archive Documents

    Directory of Open Access Journals (Sweden)

    PhD Student Laura-Rodica Hîmpa

    2016-01-01

    Full Text Available This research aims to emphasize the activity of The "Prince Carol" Royal Cultural Foundation created in 1921 in order to lead to the emancipation especially of villages, but also the Romanian culture in a more general perspective. Overall, we may say that the period between the two world wars was marked, also due to the help of the Royal Cultural Foundation, by substantial progress in various fields of education, science and culture in general and thus contributed to changing Romania into a state with a high level of culture and the creation of an image and prestige that commanded worldwide respect. The research was done on the basis of the documents studied at the Service of the National Central Historical Archives, the Stock of the "Prince Carol" Royal Cultural Foundation and at the Library of the Romanian Academy.

  19. Gurmaanlus ruulib / Marika Makarova ; kommenteerinud Anu Tali, René Uusmees, Tõnis Siigur, Hannes Võrno, Dimitri Demjanov

    Index Scriptorium Estoniae

    Makarova, Marika

    2010-01-01

    Tulevikutoidu konverentsil Tallinnas esinenud kuulsate kokkade Albert Adria, Fergus Hendersoni ja Claus Meyeri kokakunsti lähtekohtadest ja mõistet gurmaanlus mõtestavad lahti tuntud Eesti inimesed ja kokad

  20. Menea kui keskaegse slaavi-kreeka teksti üks tüüpidest / Dimitri Mironov

    Index Scriptorium Estoniae

    Mironov, Dimitri

    2000-01-01

    25. apr. 2000 toimus Tallinna Pedagoogikaülikoolis slaavi filoloogia osakonna vene keele õppetooli dotsendi Natalja Netšunajeva doktoritöö "Menea kui keskaegse slaavi-kreeka teksti üks tüüpidest" kaitsmine

  1. Recommender System for Learning SQL Using Hints

    Science.gov (United States)

    Lavbic, Dejan; Matek, Tadej; Zrnec, Aljaž

    2017-01-01

    Today's software industry requires individuals who are proficient in as many programming languages as possible. Structured query language (SQL), as an adopted standard, is no exception, as it is the most widely used query language to retrieve and manipulate data. However, the process of learning SQL turns out to be challenging. The need for a…

  2. Taso Mähar : galerii / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Taso Mähari projekteeritud töödest. 1997. a. valminud restorani Exit sisekujundusest, mis pälvis Eesti Sisearhitektide Liidu aastapreemia. Metallist ja ühest tükist väljapainutatud toolist ja samas laadis tehtud diivanist aastast 1989, mis leidsid 1992. a. aastauudistena äramärkimist ajakirjas Abitare. T. Mähari kommentaarid. 3 värv. ill

  3. Nursing knowledge: hints from the placebo effect.

    Science.gov (United States)

    Zanotti, Renzo; Chiffi, Daniele

    2017-07-01

    Nursing knowledge stems from a dynamic interplay between population-based scientific knowledge (the general) and specific clinical cases (the particular). We compared the 'cascade model of knowledge translation', also known as 'classical biomedical model' in clinical practice (in which knowledge gained at population level may be applied directly to a specific clinical context), with an emergentist model of knowledge translation. The structure and dynamics of nursing knowledge are outlined, adopting the distinction between epistemic and non-epistemic values. Then, a (moderately) emergentist approach to nursing knowledge is proposed, based on the assumption of a two-way flow from the general to the particular and vice versa. The case of the 'placebo effect' is analysed as an example of emergentist knowledge. The placebo effect is usually considered difficult to be explained within the classical biomedical model, and we underscore its importance in shaping nursing knowledge. In fact, nurses are primarily responsible for administering placebo in the clinical setting and have an essential role in promoting the placebo effect and reducing the nocebo effect. The beliefs responsible for the placebo effect are as follows: (1) interactive, because they depend on the relationship between patients and health care professionals; (2) situated, because they occur in a given clinical context related to certain rituals; and (3) grounded on higher order beliefs concerning what an individual thinks about the beliefs of others. It is essential to know the clinical context and to understand other people's beliefs to make sense of the placebo effect. The placebo effect only works when the (higher order) beliefs of doctors, nurses and patients interact in a given setting. Finally, we argue for a close relationship between placebo effect and nursing knowledge. © 2016 John Wiley & Sons Ltd.

  4. [Modifying our "obesogenic" environment: which hints?].

    Science.gov (United States)

    Masciangelo, M L; Golay, A

    2006-03-29

    Overweight is nowadays a major problem of public health in Switzerland. Swiss people eat too much, too much fat, sugar and salt! Most efficient public health strategies are global and also apply to environmental modifications, an important determinant to change individual behaviours. Today, our environment is "obesogenic": unlimited access to food, food industry marketing, lifestyle changes. As global programmes for smoking cessation and cardiovascular diseases prevention, it is urgent to propose interventions taking into account all environmental factors which could support individuals in their efforts of changes.

  5. Practical Hints on Greek and Latin

    Science.gov (United States)

    Jopes, James

    1978-01-01

    A discussion of some of the difficulties and procedures in translating classical quotations occurring in a modern text. Some of the topics covered are: use of published translations, transliteration from ancient Greek, and non-classical idioms such as medieval and botanical Latin. (AMH)

  6. Design Copyright: The Latest Judicial Hint

    OpenAIRE

    Scott Hemphill; Jeannie Suk

    2013-01-01

    The most intriguing aspect of the debate over fashion copyright is the occasion it presents for rethinking the expansive copyright law we currently have. C. Scott Hemphill (Columbia Law) & Jeannie Suk (Harvard Law)

  7. Kerjav kunstnik / Anna Hints, Maria Rõhu

    Index Scriptorium Estoniae

    Hints, Anna, 1982-

    2011-01-01

    Tallinna Linnagaleriis oli 17.03.-10.04.2011 avatud Anna Hintsi ja Maria Rõhu näitus "Nälg". Autorid näituse taotlusest, raha taotlemisest, aktsioonist "Kerjav kunstnik", külastajate suhtumisest sellesse. Näituse aruanne

  8. Observational hints on the Big Bounce

    International Nuclear Information System (INIS)

    Mielczarek, Jakub; Kurek, Aleksandra; Szydłowski, Marek; Kamionka, Michał

    2010-01-01

    In this paper we study possible observational consequences of the bouncing cosmology. We consider a model where a phase of inflation is preceded by a cosmic bounce. While we consider in this paper only that the bounce is due to loop quantum gravity, most of the results presented here can be applied for different bouncing cosmologies. We concentrate on the scenario where the scalar field, as the result of contraction of the universe, is driven from the bottom of the potential well. The field is amplified, and finally the phase of the standard slow-roll inflation is realized. Such an evolution modifies the standard inflationary spectrum of perturbations by the additional oscillations and damping on the large scales. We extract the parameters of the model from the observations of the cosmic microwave background radiation. In particular, the value of inflaton mass is equal to m = (1.7±0.6)·10 13 GeV. In our considerations we base on the seven years of observations made by the WMAP satellite. We propose the new observational consistency check for the phase of slow-roll inflation. We investigate the conditions which have to be fulfilled to make the observations of the Big Bounce effects possible. We translate them to the requirements on the parameters of the model and then put the observational constraints on the model. Based on assumption usually made in loop quantum cosmology, the Barbero-Immirzi parameter was shown to be constrained by γ < 1100 from the cosmological observations. We have compared the Big Bounce model with the standard Big Bang scenario and showed that the present observational data is not informative enough to distinguish these models

  9. Election Year Hints at Shifts for Unions

    Science.gov (United States)

    Honawar, Vaishali; Keller, Bess

    2008-01-01

    The National Education Association is poised for a change in leadership this year as its president of six years, Reg Weaver, bumps up against term limits. Now, speculation is widespread that Edward J. McElroy, his counterpart at the American Federation of Teachers, might not seek re-election in July. The possible exit of Mr. McElroy--and the…

  10. HINTS IN OMABE BASED SCULPTURE INSTALLATIONS ...

    African Journals Online (AJOL)

    ASOGWA IFEANYI

    2017-02-02

    Feb 2, 2017 ... to develop both new methods of inquiry and appropriate forms of ... sculpture, music, dance, poetry, movement, dialogue and painting. ... were feared and respected by everybody in the society, including women and children.

  11. Mõnedest küsimustest seoses kohaliku omavalitsuse korralduse seaduse uue redaktsiooniga / Vallo Olle

    Index Scriptorium Estoniae

    Olle, Vallo, 1966-

    1998-01-01

    Omavalitsusüksuse õigusaktidest, volikogu koosseisust ja pädevusest, vallavanema, linnapea jt. valla- või linnametnike ülesannetest, kohalikust eelarvest ja maksudest, omavalitsusüksuste koostööst, välissuhetest ja suhetest riigiorganitega vastavalt uuele kohaliku omavalitsuse korralduse seaduse eelnõule

  12. Maakonnaettevõtted kardavad võistelda / Siim Raie, Tea Varrak ; interv. Sulev Oll

    Index Scriptorium Estoniae

    Raie, Siim, 1977-

    2005-01-01

    Kaubandus-Tööstuskoja peadirektor Siim Raie Eesti ettevõtete konkurentsivõime edetabelist ja ettevõtluse arengust maakondades. Ettevõtluse Arendamise Sihtasutuse juhatuse esimees Tea Varrak konkursi "Ettevõtluse auhind 2005" tingimustest

  13. Ettevõtja staatust näitab auto ja telefoni omamine / Sulev Oll

    Index Scriptorium Estoniae

    Oll, Sulev, 1964-

    2000-01-01

    Fafo Rakenduslike Sotsiaaluuringute instituut Norras viis läbi elutingimuste uuringu Eesti leibkondade seas. Uuringu järgi oli ettevõtjatest eelmise aasta lõpus auto 70%, töötajaist aga alla 50%. Diagrammid

  14. Severe acute pancreatitis and selective decontamination (Results of a Illulticentel' contl'olled clinical trial)

    NARCIS (Netherlands)

    E.J.T. Luiten (Ernest)

    1998-01-01

    textabstractFrom a mild self-limiting disease, development of multiple organ failure and frequently septic complications towards a fulminant course resistant to any type of treatment, acute pancreatitis is a disorder that has numerous causes, an obscure pathogenesis and an often unpredictable

  15. Mõnedest kohaliku omavalitsusega seonduvatest õiguslikest küsimustest / Vallo Olle

    Index Scriptorium Estoniae

    Olle, Vallo, 1966-

    1997-01-01

    Valla/linna põhimääruse õiguslikust regulatsioonist, kohaliku omavalitsuse korralduse seadusest, äriseadustikust, munitsipaalettevõtete ümberkujundamisest ja nende õigusaktide väljunditest Tartu linna põhimääruses ning teistes Tartus tehtud õiguslikes otsustustes

  16. Imevaip kui majanduse šanss / Sulev Oll ; kommenteerinud Ants Reinumägi

    Index Scriptorium Estoniae

    Oll, Sulev, 1964-

    2010-01-01

    Ekspordiks tootvad Eesti ettevõtted on uuel tõuslainel - teenivad kasumit ja värbavad uusi töötajaid. Vaibatootja Narma LV, metallkonstruktsioonide valmistaja OÜ Contractor, elektrimootorite komponentide tootja AS Kolmeks

  17. Ärge võtke kasumit elujõu arvelt! / Anzori Barkalaja ; küsitlenud Sulev Oll

    Index Scriptorium Estoniae

    Barkalaja, Anzori, 1968-

    2007-01-01

    Intervjuu Tartu Ülikooli Viljandi Kultuuriakadeemia direktori Anzori Barkalajaga, kelle sõnul ei tohiks riik inimeselt, kes oma südamelähedast tööd niikuinii teeksid, elujõudu varastada ega nende arvelt kasumit võtta

  18. Maakondlik omavalitsusliit kohaliku omavalitsuse reformi kontekstis : [magistritöö] / Tõnis Roots ; Tartu Ülikool, õigusteaduskond ; juhendaja: Vallo Olle

    Index Scriptorium Estoniae

    Roots, Tõnis

    2010-01-01

    KOV süsteemi reformimist tingivatest teguritest, põhiseaduslikest tingimustest, maakondlike omavalitsusliitude õiguslikust staatusest ja pädevusest kehtivas õiguskorras ja selle muudatustest seoses kohalike omavalitsuste reformiga

  19. Mari Koger : seina sisse ehitatud akvaariumiga poissmehekodu / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    80-ruutmeetrine poissmehekorter Viimsi uues elamus. Elutoa ja vannitoa vahelises seinas paikneb kahelt poolt vaadeldav akvaarium. Magamistoa üks seintest on ehitatud vanadest tellistest. Sisearhitekt Mari Koger, tema kommentaarid. Ill.: plaan, 9 värv. vaadet

  20. HINT for Squint: A Computer Reliant Diagnostic Aid for Strabismus

    OpenAIRE

    Gieszl, Louis R.; Morris, Jacqueline; Guyton, David L.

    1983-01-01

    This paper provides an outline of methods used for the implementation of a computer reliant diagnostic aid in the medical specialty of Ophthalmology. Some problems have been associated with many previous diagnostic models. A careful review indicates that the most serious problems were:

  1. Short views and hints on information, knowledge and scenarios

    DEFF Research Database (Denmark)

    Kristiansson, Michael

    2011-01-01

    This article discusses information and knowledge in relation to scenario planning (van der Heijden) and considers the type of information that is relied on/included as well as the nature of knowledge produced by the scenario planning sequence. In addition, the chief tools and processes drawn upon...

  2. Phenomenological Hints from a Class of String Motivated Model Constructions

    Directory of Open Access Journals (Sweden)

    Hans Peter Nilles

    2015-01-01

    Full Text Available We use string theory constructions towards the generalisation of the supersymmetric standard model of strong and electroweak interactions. Properties of the models depend crucially on the location of fields in extradimensional compact space. This allows us to extract some generic lessons for the phenomenological properties of the low energy effective action. Within this scheme we present a compelling model based on local grand unification and mirage mediation of supersymmetry breakdown. We analyse the properties of the specific model towards its possible tests at the LHC and the complementarity to direct dark matter searches.

  3. Tiina Mang : vanalinna korter muutus visuaalselt suuremaks / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    74-ruutmeetrine vanalinna korter, mõeldud kahele inimesele, kellest üks töötab kodus. Enamik mööblist on valmistatud eritellimusel. Sisearhitekt Tiina Mang, tema kommentaarid. Ill.: plaan, 3 värv. vaadet

  4. Observational hints of radial migration in disc galaxies from CALIFA

    Science.gov (United States)

    Ruiz-Lara, T.; Pérez, I.; Florido, E.; Sánchez-Blázquez, P.; Méndez-Abreu, J.; Sánchez-Menguiano, L.; Sánchez, S. F.; Lyubenova, M.; Falcón-Barroso, J.; van de Ven, G.; Marino, R. A.; de Lorenzo-Cáceres, A.; Catalán-Torrecilla, C.; Costantin, L.; Bland-Hawthorn, J.; Galbany, L.; García-Benito, R.; Husemann, B.; Kehrig, C.; Márquez, I.; Mast, D.; Walcher, C. J.; Zibetti, S.; Ziegler, B.; Califa Team

    2017-07-01

    Context. According to numerical simulations, stars are not always kept at their birth galactocentric distances but they have a tendency to migrate. The importance of this radial migration in shaping galactic light distributions is still unclear. However, if radial migration is indeed important, galaxies with different surface brightness (SB) profiles must display differences in their stellar population properties. Aims: We investigate the role of radial migration in the light distribution and radial stellar content by comparing the inner colour, age, and metallicity gradients for galaxies with different SB profiles. We define these inner parts, avoiding the bulge and bar regions and up to around three disc scale lengths (type I, pure exponential) or the break radius (type II, downbending; type III, upbending). Methods: We analysed 214 spiral galaxies from the CALIFA survey covering different SB profiles. We made use of GASP2D and SDSS data to characterise the light distribution and obtain colour profiles of these spiral galaxies. The stellar age and metallicity profiles were computed using a methodology based on full-spectrum fitting techniques (pPXF, GANDALF, and STECKMAP) to the Integral Field Spectroscopic CALIFA data. Results: The distributions of the colour, stellar age, and stellar metallicity gradients in the inner parts for galaxies displaying different SB profiles are unalike as suggested by Kolmogorov-Smirnov and Anderson-Darling tests. We find a trend in which type II galaxies show the steepest profiles of all, type III show the shallowest, and type I display an intermediate behaviour. Conclusions: These results are consistent with a scenario in which radial migration is more efficient for type III galaxies than for type I systems, where type II galaxies present the lowest radial migration efficiency. In such a scenario, radial migration mixes the stellar content, thereby flattening the radial stellar properties and shaping different SB profiles. However, in light of these results we cannot further quantify the importance of radial migration in shaping spiral galaxies, and other processes, such as recent star formation or satellite accretion, might play a role. Based on observations collected at the Centro Astronómico Hispano Alemán (CAHA) at Calar Alto, operated jointly by the Max-Planck Institut für Astronomie and the Instituto de Astrofísica de Andalucía (CSIC).Table 1 is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/604/A4

  5. Observational hints of radial migration in disc galaxies from CALIFA

    NARCIS (Netherlands)

    Ruiz-Lara, T.; Pérez, I.; Florido, E.; Sánchez-Blázquez, P.; Méndez-Abreu, J.; Sánchez-Menguiano, L.; Sánchez, S. F.; Lyubenova, M.; Falcón-Barroso, J.; van de Ven, G.; Marino, R. A.; de Lorenzo-Cáceres, A.; Catalán-Torrecilla, C.; Costantin, L.; Bland-Hawthorn, J.; Galbany, L.; García-Benito, R.; Husemann, B.; Kehrig, C.; Márquez, I.; Mast, D.; Walcher, C. J.; Zibetti, S.; Ziegler, B.

    2017-01-01

    Context. According to numerical simulations, stars are not always kept at their birth galactocentric distances but they have a tendency to migrate. The importance of this radial migration in shaping galactic light distributions is still unclear. However, if radial migration is indeed important,

  6. Ageing collider throws up hint or dark matter

    CERN Multimedia

    Ananthaswamy, Anil

    2008-01-01

    "Never mind the Large Hadron Collider at CERN, its ageing predecessor may have discovered a new and unexpected kind of particle. The announcement last week from the Tevatron particle accelerator at Fermilab in Batavai, Illinois, provided some excitement amid the frustration of ongoing repairs to the LHC."

  7. A "g" beyond "Homo Sapiens"? Some Hints and Suggestions

    Science.gov (United States)

    Lee, James J.

    2007-01-01

    This article proposes that a complete account of cognitive evolution may have to accommodate a domain-general source of variance in mental abilities accounting for differences among primate taxa. Deaner, van Schaik, and Johnson [Deaner, R.O., van Schaik, C.P. and Johnson, V.E. (2006). Do some taxa have better domain-general cognition than others?…

  8. Hints for electric-field compensation in multicell resonant structures

    Energy Technology Data Exchange (ETDEWEB)

    Fernandes, P; Parodi, R

    1981-03-31

    We propose a lumped-parameter equivalent circuit for a TM/sub 01/ multicell standing wave accelerating structure with full end cells. By the suggested model we can predict the amount of end cell frequency compensation needed to achieve field flatness in the highest mode of the structure.

  9. An Impending geomagnetic transition? Hints from the past.

    Directory of Open Access Journals (Sweden)

    Carlo eLAJ

    2015-10-01

    Full Text Available The rapid decrease of the geomagnetic field intensity in the last centuries has led to speculations that an attempt to a reversal or an excursion might be under way. Here we investigate this hypothesis by examining past records of geomagnetic field intensity obtained from sedimentary cores and from the study of cosmogenic nuclides. The selected records describe geomagnetic changes with an unprecedented temporal resolution between 20 and 75 kyr B.P. We find that some aspects of the present-day geomagnetic field have some similarities with those documented for the Laschamp excursion 41 kyr ago. Under the assumption that the dynamo processes for an eventual future reversal or excursion would be similar to those of the Laschamp excursion, we tentatively suggest that, whilst irreversible processes that will drive the geodynamo into a polarity change may have already started, a reversal or an excursion should not be expected before 500 to 1000 years.

  10. An impending geomagnetic transition? Hints from the past

    OpenAIRE

    Laj, Carlo; Kissel, Catherine

    2015-01-01

    The rapid decrease of the geomagnetic field intensity in the last centuries has led to speculations that an attempt to a reversal or an excursion might be under way. Here we investigate this hypothesis by examining past records of geomagnetic field intensity obtained from sedimentary cores and from the study of cosmogenic nuclides. The selected records describe geomagnetic changes with an unprecedented temporal resolution between 20 and 75 kyr B.P. We find that some aspects of the present-day...

  11. Learning To Learn: 15 Vocabulary Acquisition Activities. Tips and Hints.

    Science.gov (United States)

    Holden, William R.

    1999-01-01

    This article describes a variety of ways learners can help themselves remember new words, choosing the ones that best suit their learning styles. It is asserted that repeated exposure to new lexical items using a variety of means is the most consistent predictor of retention. The use of verbal, visual, tactile, textual, kinesthetic, and sonic…

  12. Food Safety and Quality Control: Hints from Proteomics

    Directory of Open Access Journals (Sweden)

    Angelo D'Alessandro

    2012-01-01

    Full Text Available Over the last decade, proteomics has been successfully applied to the study of quality control in production processes of food (including meat, wine and beer, transgenic plants and milk and food safety (screening for food-derived pathogens. Indeed, food quality and safety and their influence on the health of end consumers have growingly become a founding principle in the international agenda of health organizations. The application of proteomics in food science was at first characterized by exploratory analyses of food of various origin (bovine, swine, chicken or lamb meat, but also transgenic food such as genetically modified maize, for example and beverages (beer, wine, in parallel to the genomic and transcriptomic approaches seeking determination of quantitative trait loci. In the last few years, technical improvements such as microbial biotyping strategies have growingly allowed proteomicists to address the safety issue as well. The newly introduced technical improvements (instrumentation characterized by higher sensitivity such as mass spectrometers have paved the way for the individuation of food-contaminating pathogens in a fast and efficient workflow which is mandatory in industrial food production chains.

  13. HINT-KB: The human interactome knowledge base

    KAUST Repository

    Theofilatos, Konstantinos A.; Dimitrakopoulos, Christos M.; Kleftogiannis, Dimitrios A.; Moschopoulos, Charalampos N.; Papadimitriou, Stergios; Likothanassis, Spiridon D.; Mavroudi, Seferina P.

    2012-01-01

    Proteins and their interactions are considered to play a significant role in many cellular processes. The identification of Protein-Protein interactions (PPIs) in human is an open research area. Many Databases, which contain information about

  14. Using peer instruction with hints in introductory business statistics

    NARCIS (Netherlands)

    Ding, Ning; Xu, Xiaoyan

    2014-01-01

    Abstract:Purpose – Peer instruction has been widely adopted as an instructional method in higher education. However, due to students' different preconceptions, the authors argued that peer instruction is not a panacea in international business education when students' prior knowledge extensively

  15. What Caused the Recession of 2008? Hints from Labor Productivity

    OpenAIRE

    Casey Mulligan

    2009-01-01

    A labor market tautology says that any change in labor usage can be decomposed into a movement along a marginal productivity schedule and a shift of the schedule. I calculate this decomposition for the recession of 2008, assuming an aggregate Cobb-Douglas marginal productivity schedule, and find that all of the decline in employment and hours since December 2007 is a movement along the schedule. This finding suggests that a reduction in labor supply and/or an increase in labor market distorti...

  16. Mari Koger : "Arhitekte on palju. Tuleb leida õige" / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Mari Koger (sünd. 1973) kodu kujundamisest, planeerimisest, valgustusest, värvidest, suhtlemisest kliendiga. Mari Kogerist, loetletud tema tehtud ühiskondlike ruumide sisekujundused aastast 2002. M. Koger töötab Boom.ee OÜ-s. Ill.: M. Kogeri värv. portree

  17. Remembering Multiple Passwords by Way of Minimal-Feedback Hints

    DEFF Research Database (Denmark)

    Hertzum, Morten

    2004-01-01

    Passwords are a prominent mechanism for user authentication but entail a conflict between ease of use and security in that passwords must be both easy to remember for the password holder and difficult to guess for everybody else. To support users in remembering their passwords minimal-feedback...

  18. Brotze väljaande filoloogilisi probleeme / Mati Hint

    Index Scriptorium Estoniae

    Hint, Mati

    2007-01-01

    Rets. rmt. : Johann Christoph Brotze. Estonica. Koostanud / Herausgegeben von Ants Hein, Ivar Leimus, Raimo Pullat, Ants Viires. Projektijuht ja vastutav toimetaja : Raimo Pullat. tõlge eesti keelde: Tõnis Liibek, Ivar Leimus, tõlge saksa keelde: Aigi Heero, Ene Rõngelep. Kujundus: Andres Tali. Tallinn : Estopol OÜ, 2006. XXXVI, 619 lk. Teoses esinevaid keele- ja kohanimeprobleeme

  19. Aet Piel : oluline sisekujunduselement on viltune sein / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Poolkaares ehitatud korterelamus on Aet Pieli kujundatud korteris üks sein viltu. Esmapilgul häirivana mõjunud sein sai oluliseks sisekujunduselemendiks. Eritellimusel valmistatud mööbel on tammepuidust. A. Pieli kommentaarid. Ill.: plaan enne ja nüüd, 9 värv. vaadet

  20. Sanitation and recultivation of the Endlhausen landfill. Experience and hints

    Energy Technology Data Exchange (ETDEWEB)

    Hoerich, O; Rieger, W

    1986-02-01

    A landfill located in a former gravel pit was covered once 300,000 t of domestic refuse had been dumped. Drain pipes were laid for degassing the landfill. A clay layer was used to prevent surface water inroads. The article explains details and approaches. The cost are some DM 900,000 at an area of 3 ha. Grassing and planting will follow.

  1. 200 more puzzling physics problems with hints and solutions

    CERN Document Server

    Gnädig, Péter; Vigh, Máté

    2016-01-01

    Like its predecessor, 200 Puzzling Physics Problems, this book is aimed at strengthening students' grasp of the laws of physics by applying them to situations that are practical, and to problems that yield more easily to intuitive insight than to brute-force methods and complex mathematics. The problems are chosen almost exclusively from classical, non-quantum physics, but are no easier for that. They are intriguingly posed in accessible non-technical language, and require readers to select an appropriate analysis framework and decide which branches of physics are involved. The general level of sophistication needed is that of the exceptional school student, the good undergraduate, or the competent graduate student; some physics professors may find some of the more difficult questions challenging. By contrast, the mathematical demands are relatively minimal, and seldom go beyond elementary calculus. This further book of physics problems is not only instructive and challenging, but also enjoyable.

  2. Riemannian geometry of Hamiltonian chaos: hints for a general theory.

    Science.gov (United States)

    Cerruti-Sola, Monica; Ciraolo, Guido; Franzosi, Roberto; Pettini, Marco

    2008-10-01

    We aim at assessing the validity limits of some simplifying hypotheses that, within a Riemmannian geometric framework, have provided an explanation of the origin of Hamiltonian chaos and have made it possible to develop a method of analytically computing the largest Lyapunov exponent of Hamiltonian systems with many degrees of freedom. Therefore, a numerical hypotheses testing has been performed for the Fermi-Pasta-Ulam beta model and for a chain of coupled rotators. These models, for which analytic computations of the largest Lyapunov exponents have been carried out in the mentioned Riemannian geometric framework, appear as paradigmatic examples to unveil the reason why the main hypothesis of quasi-isotropy of the mechanical manifolds sometimes breaks down. The breakdown is expected whenever the topology of the mechanical manifolds is nontrivial. This is an important step forward in view of developing a geometric theory of Hamiltonian chaos of general validity.

  3. Tunne bossanova plaadiümbriselt / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2004-01-01

    Kahekorruseline eramu (285 m2), mille merepoolne sein on klaasist. Läbiv idee - silmside loodusega. Arhitekt ja sisearhitekt Tarmo Piirmets, tema kommentaar. Ill.: I ja II korruse plaan, 13 värv. vaadet

  4. Taso Mähar : avatud vannitoaga vanalinna korter / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Modernne korter (220 m2). Sisearhitekt Taso Mähar, tema kommentaarid. Kogu korteri ulatuses on sisekujundusmaterjalidena kasutatud väärispuitu, metalli, marmorit ja klaasi. T. Mähari projekteeritud on trepp ja piirded, kamin, baarilett ja õhukesed alumiiniumraamidel mattklaasidega uksed. Ill.: I ja II korruse plaan, 8 värv. vaadet

  5. New planet hints at life in the stars

    CERN Multimedia

    Dalton, A W

    2002-01-01

    Astronomers have detected a distant planet 100 light years from Earth, circling Tau1 Gruis, its star, in the constellation of Grus (the crane). The planet, similar in appearance to Jupiter, is three times as far away from its star as the Earth is from the Sun and takes four years to revolve around the star, in a roughly circular orbit. Scientists believe this type of planetary orbit is the most promising for finding worlds that contain life (1 page).

  6. New physics hints in B decays and collider outlook

    Indian Academy of Sciences (India)

    Less noticed is the difference in direct CPV (DCPV) asymmetries in B0 ... Our working picture is that squarks are relatively degenerate at some ... We stress that the new (and unique!) ..... [1] See http://mlm.home.cern.ch/mlm/FlavLHC.html.

  7. "To Improve upon Hints of Things": Illustrating Isaac Newton.

    Science.gov (United States)

    Schilt, Cornelis J

    2016-01-01

    When Isaac Newton died in 1727 he left a rich legacy in terms of draft manuscripts, encompassing a variety of topics: natural philosophy, mathematics, alchemy, theology, and chronology, as well as papers relating to his career at the Mint. One thing that immediately strikes us is the textuality of Newton's legacy: images are sparse. Regarding his scholarly endeavours we witness the same practice. Newton's extensive drafts on theology and chronology do not contain a single illustration or map. Today we have all of Newton's draft manuscripts as witnesses of his working methods, as well as access to a significant number of books from his own library. Drawing parallels between Newton's reading practices and his natural philosophical and scholarly work, this paper seeks to understand Newton's recondite writing and publishing politics.

  8. DEMYSTIFYING QUANTUM MECHANICS: Will there be hints from LHC?

    CERN Multimedia

    CERN. Geneva

    2007-01-01

    All modern theories for particles, forces and even space-time itself, use the framework provided by quantum mechanics. The Standard Model is a quantized field theory. Even superstring theory is based on quantum mechanics. There is something odd about quantum mechanics: it brilliantly allows us to predict the outcome of experiments, yet it gives confusing statements about what really is going on inside particles and fields. Suppose we would be asking for a theory that allows us to describe what actually happens in less ambiguous terms, without destroying the magnificent successes of quantum mechanics, would this help us to answer some of the great mysteries of theoretical elementary particle physics?Organiser(s): L. Alvarez-Gaume / PH-THNote: * Tea & coffee will be served at 16:00.

  9. Effect of Sibutramine on Plasma C-Reactive Protein, Leptin and Adipon ectin Concentrations: A Systematic Review and Meta-Analysis of Randomized Contr olled Trials.

    Science.gov (United States)

    De Vincentis, Antonio; Pedone, Claudio; Vespasiani-Gentilucci, Umberto; Picardi, Antonio; Derosa, Giuseppe; Maffioli, Pamela; Sahebkar, Amirhossein

    2017-01-01

    Sibutramine is an anti-obesity medication whose effects on weight loss have been widely explored. Moreover, limited number of studies also evidenced its correlates on adipokines and proinflammatory markers; however, their results have not been conclusive. Hence, a systematic review and meta-analysis of available evidence was conducted in order to calculate the effect size of sibutramine therapy on C-reactive protein (CRP), leptin and adiponectin concentrations. Seven randomized clinical trials with a total of 601 subjects met the eligibility criteria. Random effect meta-analysis evidenced a significant decrease in plasma levels of CRP and leptin (weighted mean difference [WMD] -15.58%, 95% confidence interval [95%CI]: -28.84, -2.33, p=0.021 and WMD -9.25, 95%CI: -15.73, -2.78, p=0.005, respectively) and increase of adiponectin (WMD 9.86%, 95%CI: 1.76, 17.96, p=0.017) following sibutramine therapy. Subgroup analysis showed a greater CRP-lowering effect of sibutramine with doses sibutramine. Possible impacts and relevance of these alterations on cardiovascular risk profile remain to be clarified, especially in post-hoc analyses of sibutramine outcome trials among people without pre-existing cardiovascular disease. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  10. Basics of compounding: Tips and hints: powders, capsules, tablets, suppositories, and sticks, part 1.

    Science.gov (United States)

    Allen, Loyd V

    2014-01-01

    No matter the profession, professionals should never stop learning. This is especially true and important in the profession of compounding pharmacy. Compounding pharmacists are continuously faced with the challenge of finding new and inventive ways to assist patients with their individual and specific drug requirements. As compounding pharmacists learn, be it through formal continuing education or experience, they should be willing to share their knowledge with other compounders. In our goal of providing compounding pharmacists with additional knowledge to improve their skills in the art and practice of compounding, this article, which provides tips and hits on compounding with powders, capsules, tablets, suppositories, and sticks, represents the first in a series of articles to assist compounding pharmacists in the preparation of compounded medications.

  11. Design of sweet protein based sweeteners: hints from structure-function relationships.

    Science.gov (United States)

    Rega, Michele Fortunato; Di Monaco, Rossella; Leone, Serena; Donnarumma, Federica; Spadaccini, Roberta; Cavella, Silvana; Picone, Delia

    2015-04-15

    Sweet proteins represent a class of natural molecules, which are extremely interesting regarding their potential use as safe low-calories sweeteners for individuals who need to control sugar intake, such as obese or diabetic subjects. Punctual mutations of amino acid residues of MNEI, a single chain derivative of the natural sweet protein monellin, allow the modulation of its taste. In this study we present a structural and functional comparison between MNEI and a sweeter mutant Y65R, containing an extra positive charge on the protein surface, in conditions mimicking those of typical beverages. Y65R exhibits superior sweetness in all the experimental conditions tested, has a better solubility at mild acidic pH and preserves a significant thermal stability in a wide range of pH conditions, although slightly lower than MNEI. Our findings confirm the advantages of structure-guided protein engineering to design improved low-calorie sweeteners and excipients for food and pharmaceutical preparations. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. The infrared medium-deep survey. II. How to trigger radio AGNs? Hints from their environments

    Energy Technology Data Exchange (ETDEWEB)

    Karouzos, Marios; Im, Myungshin; Kim, Jae-Woo; Lee, Seong-Kook; Jeon, Yiseul; Choi, Changsu; Hong, Jueun; Hyun, Minhee; Jun, Hyunsung David; Kim, Dohyeong; Kim, Yongjung; Kim, Ji Hoon; Kim, Duho; Park, Won-Kee; Taak, Yoon Chan; Yoon, Yongmin [CEOU—Astronomy Program, Department of Physics and Astronomy, Seoul National University, Gwanak-gu, Seoul 151-742 (Korea, Republic of); Chapman, Scott [Department of Physics and Atmospheric Science, Dalhousie University, Halifax, Nova Scotia (Canada); Pak, Soojong [School of Space Research, Kyung Hee University, Yongin-si, Gyeonggi-do 446-701 (Korea, Republic of); Edge, Alastair, E-mail: mkarouzos@astro.snu.ac.kr [Department of Physics, University of Durham, South Road, Durham, DH1 3LE (United Kingdom)

    2014-12-10

    Activity at the centers of galaxies, during which the central supermassive black hole is accreting material, is nowadays accepted to be rather ubiquitous and most probably a phase of every galaxy's evolution. It has been suggested that galactic mergers and interactions may be the culprits behind the triggering of nuclear activity. We use near-infrared data from the new Infrared Medium-Deep Survey and the Deep eXtragalactic Survey of the VIMOS-SA22 field and radio data at 1.4 GHz from the FIRST survey and a deep Very Large Array survey to study the environments of radio active galactic nuclei (AGNs) over an area of ∼25 deg{sup 2} and down to a radio flux limit of 0.1 mJy and a J-band magnitude of 23 mag AB. Radio AGNs are predominantly found in environments similar to those of control galaxies at similar redshift, J-band magnitude, and (M{sub u} – M{sub r} ) rest-frame color. However, a subpopulation of radio AGNs is found in environments up to 100 times denser than their control sources. We thus preclude merging as the dominant triggering mechanism of radio AGNs. By fitting the broadband spectral energy distribution of radio AGNs in the least and most dense environments, we find that those in the least dense environments show higher radio-loudness, higher star formation efficiencies, and higher accretion rates, typical of the so-called high-excitation radio AGNs. These differences tend to disappear at z > 1. We interpret our results in terms of a different triggering mechanism for these sources that is driven by mass loss through winds of young stars created during the observed ongoing star formation.

  13. Hints for Small Disks around Very Low Mass Stars and Brown Dwarfs

    International Nuclear Information System (INIS)

    Hendler, Nathanial P.; Mulders, Gijs D.; Pascucci, Ilaria; Greenwood, Aaron; Kamp, Inga; Henning, Thomas; Ménard, François; Dent, William R. F.; II, Neal J. Evans

    2017-01-01

    The properties of disks around brown dwarfs and very low mass stars (hereafter VLMOs) provide important boundary conditions on the process of planet formation and inform us about the numbers and masses of planets than can form in this regime. We use the Herschel Space Observatory PACS spectrometer to measure the continuum and [O i] 63 μ m line emission toward 11 VLMOs with known disks in the Taurus and Chamaeleon I star-forming regions. We fit radiative transfer models to the spectral energy distributions of these sources. Additionally, we carry out a grid of radiative transfer models run in a regime that connects the luminosity of our sources with brighter T Tauri stars. We find that VLMO disks with sizes 1.3–78 au, smaller than typical T Tauri disks, fit well the spectral energy distributions assuming that disk geometry and dust properties are stellar mass independent. Reducing the disk size increases the disk temperature, and we show that VLMOs do not follow previously derived disk temperature–stellar luminosity relationships if the disk outer radius scales with stellar mass. Only 2 out of 11 sources are detected in [O i] despite a better sensitivity than was achieved for T Tauri stars, suggesting that VLMO disks are underluminous. Using thermochemical models, we show that smaller disks can lead to the unexpected [O i] 63 μ m nondetections in our sample. The disk outer radius is an important factor in determining the gas and dust observables. Hence, spatially resolved observations with ALMA—to establish if and how disk radii scale with stellar mass—should be pursued further.

  14. Tandem mass spectrometry of nitric oxide and hydrogen sulfide releasing aspirins: a hint into activity behavior.

    Science.gov (United States)

    Crestoni, Maria Elisa; Chiavarino, Barbara; Guglielmo, Stefano; Lilla, Valentina; Fornarini, Simonetta

    2013-01-01

    Aspirin (acetylsalicylic acid, ASA) is the most popular non-steroidal anti-inflammatory drug. However, due to its action on cyclooxygenase and its acid nature, aspirin is associated with adverse gastrointestinal effects. In an effort to minimize these side effects, NO-donor and H2S-donor ASA co-drugs have been designed and tested. Their mass spectrometric behavior is now analyzed and reported. Positive ions were obtained by electrospray ionization involving protonation or alkali metal attachment. Their dissociation processes have been studied by collision induced dissociation in a triple quadrupole instrument. High mass accuracy measurements have been recorded on a Fourier transform ion cyclotron resonance mass spectrometer. The protonated molecules dissociate by an exclusive or largely prevailing path leading to acetyloxy-substituted benzoyl cation, namely an ASA unit. The process is reminiscent of the enzymatic hydrolysis, releasing intact ASA to a large extent. Only at higher collision energy does the formal ketene loss disrupt the ASA moiety. The gas phase chemistry of protonated ASA-releasing drugs develops along elementary dissociation steps analogous to the reactive processes in complex biological environments. This notion may provide a tool for preliminary testing of new compounds.

  15. Riia Oja : "Ruumi lihtsusel on korrastav mõju mõtetele" / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Riia Oja (sünd. 1967) valgustusest kui miljöö loojast, materjalidest, eramu projekteerimisest. Riia Ojast, kes töötab 1991. aastast sisearhitektuuribüroos AS Stuudio Gadis. Ill.: R. Oja värv. portree

  16. Is the CMS e e j j excess a hint for light supersymmetry?

    Science.gov (United States)

    Krauss, Manuel E.; Porod, Werner

    2015-09-01

    We discuss the impact of additional two-body decays of the right-handed neutrino into a light charged Higgs state on the dilepton plus dijet cross sections from resonant W' production. We consider in particular a supersymmetric left-right symmetric model which predicts such a light charged Higgs boson. We demonstrate that the e e j j excess as measured by CMS can be explained best if the W' also has decay modes into Higgsino-like charginos and neutralinos with masses of a few hundred GeV. Provided that this excess is confirmed, the model predicts also one right-handed neutrino with a mass below 200 GeV as well as a doubly charged Higgs boson which should be discovered at the LHC in the near future.

  17. Building Models to Predict Hint-or-Attempt Actions of Students

    Science.gov (United States)

    Castro, Francisco Enrique Vicente; Adjei, Seth; Colombo, Tyler; Heffernan, Neil

    2015-01-01

    A great deal of research in educational data mining is geared towards predicting student performance. Bayesian Knowledge Tracing, Performance Factors Analysis, and the different variations of these have been introduced and have had some success at predicting student knowledge. It is worth noting, however, that very little has been done to…

  18. Search for Z′, vacuum (instability and hints of high-energy structures

    Directory of Open Access Journals (Sweden)

    Accomando Elena

    2016-01-01

    Full Text Available We study the high-energy behaviour of a class of anomaly-free abelian extensions of the Standard Model. We focus on the interplay among the phenomenological characterisation of the model and the use of precise renormalisation group methods. Using as boundary conditions regions of the parameter space at the verge of current LHC probe, interesting unification patterns emerge linked to thresholds belonging to a SO(10 grand unification theory (GUT. We stress how the evolution of the mixing between the two abelian factors may provide a valuable tool to address the candidate high-energy embedding. The emerging unification scenarios are then challenged to be perturbative and to allow for a stable vacuum.

  19. Looking at learning communities with the appropriate glasses: hints and ideas from network sciences

    Directory of Open Access Journals (Sweden)

    Fabio Nascimbeni

    2013-02-01

    Full Text Available 0 0 1 229 1263 USAL 10 2 1490 14.0 Normal 0 21 false false false ES JA X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin-top:0cm; mso-para-margin-right:0cm; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0cm; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:Calibri; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-ansi-language:ES; mso-fareast-language:EN-US;} The level of network thinking within education – intended as the capacity to look at learning systems and communities by focussing on the relations among the involved actors (primarily teachers and learners and not only on the actors characteristics – is growing, with different speeds depending on the educational sector, but not at the pace needed to keep up with the increasingly network nature of our societies. We claim that educational research and practices should increase their capacity to look at learning communities through appropriate “networking-sensitive” glasses, and get equipped with tools and methods – such as Social network Analysis - to properly understand and support these networks. The application of Social Network Analysis to education, especially in the case of distance learning, can allow understanding the patterns of interactions between teachers and learners, and can facilitate the consolidation of new approaches to understand collaboration mechanisms. The paper presents and discusses - from a learning viewpoint - a brief overview of the main theoretical and practical contributions coming from Social Network Analysis – such as the “random graphs”, the “small-worlds” or the “weak-ties” theories – together with some general properties and dynamics of networks, believing that mastering these dynamics is extremely important for educational researchers and practitioners, when it comes to understanding and supporting meaningful collaborative learning.

  20. 76 FR 22714 - Proposed Collection; Comment Request; Health Information National Trends Survey 4 (HINTS 4) (NCI)

    Science.gov (United States)

    2011-04-22

    ... questions with inquiries into the communication channels through which understanding is being obtained, and... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Proposed Collection; Comment... content of the survey will focus on understanding the degree to which members of the general population...

  1. Human airway epithelial cells investigated by atomic force microscopy: A hint to cystic fibrosis epithelial pathology

    Energy Technology Data Exchange (ETDEWEB)

    Lasalvia, Maria [Department of Clinical and Experimental Medicine, University of Foggia, Foggia (Italy); Istituto Nazionale di Fisica Nucleare, Sezione di Bari, Bari (Italy); Castellani, Stefano [Department of Medical and Surgical Sciences, University of Foggia, Foggia (Italy); D’Antonio, Palma [Department of Clinical and Experimental Medicine, University of Foggia, Foggia (Italy); Perna, Giuseppe [Department of Clinical and Experimental Medicine, University of Foggia, Foggia (Italy); Istituto Nazionale di Fisica Nucleare, Sezione di Bari, Bari (Italy); Carbone, Annalucia [Department of Medical and Surgical Sciences, University of Foggia, Foggia (Italy); Colia, Anna Laura; Maffione, Angela Bruna [Department of Clinical and Experimental Medicine, University of Foggia, Foggia (Italy); Capozzi, Vito [Department of Clinical and Experimental Medicine, University of Foggia, Foggia (Italy); Istituto Nazionale di Fisica Nucleare, Sezione di Bari, Bari (Italy); Conese, Massimo, E-mail: massimo.conese@unifg.it [Department of Medical and Surgical Sciences, University of Foggia, Foggia (Italy)

    2016-10-15

    The pathophysiology of cystic fibrosis (CF) airway disease stems from mutations in the CF Transmembrane Conductance Regulator (CFTR) gene, leading to a chronic respiratory disease. Actin cytoskeleton is disorganized in CF airway epithelial cells, likely contributing to the CF-associated basic defects, i.e. defective chloride secretion and sodium/fluid hypersorption. In this work, we aimed to find whether this alteration could be pointed out by means of Atomic Force Microscopy (AFM) investigation, as roughness and Young's elastic module. Moreover, we also sought to determine whether disorganization of actin cytoskeleton is linked to hypersoption of apical fluid. Not only CFBE41o- (CFBE) cells, immortalized airway epithelial cells homozygous for the F508del CFTR allele, showed a different morphology in comparison with 16HBE14o- (16HBE) epithelial cells, wild-type for CFTR, but also they displayed a lack of stress fibers, suggestive of a disorganized actin cytoskeleton. AFM measurements showed that CFBE cells presented a higher membrane roughness and decreased rigidity as compared with 16HBE cells. CFBE overexpressing wtCFTR became more elongated than the parental CFBE cell line and presented actin stress fibers. CFBE cells absorbed more fluid from the apical compartment. Study of fluid absorption with the F-actin-depolymerizing agent Latrunculin B demonstrated that actin cytoskeletal disorganization increased fluid absorption, an effect observed at higher magnitude in 16HBE than in CFBE cells. For the first time, we demonstrate that actin cytoskeleton disorganization is reflected by AFM parameters in CF airway epithelial cells. Our data also strongly suggest that the lack of stress fibers is involved in at least one of the early step in CF pathophysiology at the levels of the airways, i.e. fluid hypersorption. - Highlights: • CF bronchial epithelial (CFBE) cells show a disorganized actin cytoskeleton. • CFBE cells present high roughness and low rigidity in the plasmamembrane. • CFTR overexpression changes morphology and actin organization. • CFBE cells absorb more apical fluid than wild type bronchial epithelial cells. • Fluid absorption is increased by disorganization of actin cytoskeleton.

  2. Hints on the Nature of Dark Matter from the Properties of Milky Way Satellites

    NARCIS (Netherlands)

    Anderhalden, D.; Schneider, A.; Macciò, A.V.; Diemand, J.; Bertone, G.

    2013-01-01

    The nature of dark matter is still unknown and one of the most fundamental scientific mysteries. Although successfully describing large scales, the standard cold dark matter model (CDM) exhibits possible shortcomings on galactic and sub-galactic scales. It is exactly at these highly non-linear

  3. Ultra high energy cosmic rays above 10 GeV: Hints to new physics ...

    Indian Academy of Sciences (India)

    Ultra high energy cosmic rays; physics beyond standard model. ... The origin of the observed cosmic ray (CR) events above 10ѕј eV — the so-called ex- .... to arise simply from decay of some supermassive particles (of mass> 10ѕЅ eV) ...

  4. Immunotherapeutic Potential of Oncolytic H-1 Parvovirus: Hints of Glioblastoma Microenvironment Conversion towards Immunogenicity.

    Science.gov (United States)

    Angelova, Assia L; Barf, Milena; Geletneky, Karsten; Unterberg, Andreas; Rommelaere, Jean

    2017-12-15

    Glioblastoma, one of the most aggressive primary brain tumors, is characterized by highly immunosuppressive microenvironment. This contributes to glioblastoma resistance to standard treatment modalities and allows tumor growth and recurrence. Several immune-targeted approaches have been recently developed and are currently under preclinical and clinical investigation. Oncolytic viruses, including the autonomous protoparvovirus H-1 (H-1PV), show great promise as novel immunotherapeutic tools. In a first phase I/IIa clinical trial (ParvOryx01), H-1PV was safe and well tolerated when locally or systemically administered to recurrent glioblastoma patients. The virus was able to cross the blood-brain (tumor) barrier after intravenous infusion. Importantly, H-1PV treatment of glioblastoma patients was associated with immunogenic changes in the tumor microenvironment. Tumor infiltration with activated cytotoxic T cells, induction of cathepsin B and inducible nitric oxide (NO) synthase (iNOS) expression in tumor-associated microglia/macrophages (TAM), and accumulation of activated TAM in cluster of differentiation (CD) 40 ligand (CD40L)-positive glioblastoma regions was detected. These are the first-in-human observations of H-1PV capacity to switch the immunosuppressed tumor microenvironment towards immunogenicity. Based on this pilot study, we present a tentative model of H-1PV-mediated modulation of glioblastoma microenvironment and propose a combinatorial therapeutic approach taking advantage of H-1PV-induced microglia/macrophage activation for further (pre)clinical testing.

  5. Taso Mähar : maali ümber ehitatud maja / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    220-ruutmeetrise ühekorde eramu sisekujundus. Arhitekt Emil Urbel. Sisearhitekt Taso Mähar, tema kommentaarid. Köögimööbel on T. Mähari projekteeritud. Elutoas mööblifirma T&T Mang pehme mööbel, seinal Lemming Nageli maal "Punane joon all - Burn Out". Ill.: plaan, 17 värv. vaadet

  6. Understanding Public Engagement in Water Conservation Behaviors and Knowledge of Water Policy: Promising Hints for Extension

    Science.gov (United States)

    Huang, Pei-wen; Lamm, Alexa J.

    2015-01-01

    Sustaining water resources is a primary issue facing Florida Extension. The study reported here identified how experience with water issues and familiarity with water policies affected individuals' engagement in water conservation behaviors. A public opinion survey was conducted online to capture Florida residents' responses. The findings…

  7. Melatonin, Noncoding RNAs, Messenger RNA Stability and Epigenetics—Evidence, Hints, Gaps and Perspectives

    Directory of Open Access Journals (Sweden)

    Rüdiger Hardeland

    2014-10-01

    Full Text Available Melatonin is a highly pleiotropic regulator molecule, which influences numerous functions in almost every organ and, thus, up- or down-regulates many genes, frequently in a circadian manner. Our understanding of the mechanisms controlling gene expression is actually now expanding to a previously unforeseen extent. In addition to classic actions of transcription factors, gene expression is induced, suppressed or modulated by a number of RNAs and proteins, such as miRNAs, lncRNAs, piRNAs, antisense transcripts, deadenylases, DNA methyltransferases, histone methylation complexes, histone demethylases, histone acetyltransferases and histone deacetylases. Direct or indirect evidence for involvement of melatonin in this network of players has originated in different fields, including studies on central and peripheral circadian oscillators, shift work, cancer, inflammation, oxidative stress, aging, energy expenditure/obesity, diabetes type 2, neuropsychiatric disorders, and neurogenesis. Some of the novel modulators have also been shown to participate in the control of melatonin biosynthesis and melatonin receptor expression. Future work will need to augment the body of evidence on direct epigenetic actions of melatonin and to systematically investigate its role within the network of oscillating epigenetic factors. Moreover, it will be necessary to discriminate between effects observed under conditions of well-operating and deregulated circadian clocks, and to explore the possibilities of correcting epigenetic malprogramming by melatonin.

  8. HEALTH INFO SANTE ANNUAL DEDUCTIBLE AND REIMBURSEMENT CLAIMS: HINTS FOR USE

    CERN Multimedia

    1999-01-01

    Information from the CHIS Board and the Personnel DivisionOne should bear in mind that the annual deductible is an amount (currently CHF 100) charged automatically by the Administrator of the scheme for every adult aged 18 and above. This is what happens: The amount is deducted annually for all medical services received over a calendar year.It is triggered by the date of the treatment and not by the date of the bill nor that of the reimbursement claim.In other words, if you receive medical treatment in December for the first time in a given year, the CHF 100 will be deducted from the claim for that treatment. So, except for urgent cases, it would be better to wait till the following month, thus avoiding one annual deductible.It is also worth remembering that the cost of processing our reimbursement claims - and there were 55, 000 in 1998 - is part of the cost of our insurance.Help keep administrative costs down : do not submit reimbursement claims for amounts less than the annual deductible unless your claims...

  9. An overview of MR arthrography with emphasis on the current technique and applicational hints and tips

    International Nuclear Information System (INIS)

    Sahin, Guelden; Demirtas, Mehmet

    2006-01-01

    Magnetic resonance (MR) arthrography has been investigated in every major peripheral joint of the body, and has been proven to be effective in determining the integrity of intraarticular ligamentous and fibrocartilaginous structures and in the detection or assessment of osteochondral lesions and loose bodies in selected cases. Several methods could be used to create arthrogram effect during MR imaging, however, direct MR arthrography using diluted gadolinium as the contrast agent is the most commonly used technique and is the most reliable of all. MR arthrography is useful for demonstrating labrocapsular-ligamentous abnormalities and distinguishing partial thickness rotator cuff tears from focal full thickness tears in the shoulder, identifying or excluding recurrent tears following meniscal operations in the knee, demonstrating perforations of the triangular fibrocartilage complex (TFCC) and ligaments in the wrist, showing labral tears in the hip, diagnosing ligament tears in the ankle and identifying osteochondral lesions or loose bodies in any of the aforementioned joints. In this article, an overview of techniques of MR arthrography is provided with emphasis on direct MR arthrography using diluted gadolinium as the contrast agent. The current applications of the technique in major peripheral joints are reviewed, with emphasis given to the shoulder joint where the role of this technique has become well established

  10. IceCube events and decaying dark matter: hints and constraints

    Science.gov (United States)

    Esmaili, Arman; Kang, Sin Kyu; Dario Serpico, Pasquale

    2014-12-01

    In the light of the new IceCube data on the (yet unidentified) astrophysical neutrino flux in the PeV and sub-PeV range, we present an update on the status of decaying dark matter interpretation of the events. In particular, we develop further the angular distribution analysis and discuss the perspectives for diagnostics. By performing various statistical tests (maximum likelihood, Kolmogorov-Smirnov and Anderson-Darling tests) we conclude that currently the data show a mild preference (below the two sigma level) for the angular distribution expected from dark matter decay vs. the isotropic distribution foreseen for a conventional astrophysical flux of extragalactic origin. Also, we briefly develop some general considerations on heavy dark matter model building and on the compatibility of the expected energy spectrum of decay products with the IceCube data, as well as with existing bounds from gamma-rays. Alternatively, assuming that the IceCube data originate from conventional astrophysical sources, we derive bounds on both decaying and annihilating dark matter for various final states. The lower limits on heavy dark matter lifetime improve by up to an order of magnitude with respect to existing constraints, definitively making these events—even if astrophysical in origin—an important tool for astroparticle physics studies.

  11. IceCube events and decaying dark matter: hints and constraints

    International Nuclear Information System (INIS)

    Esmaili, Arman; Kang, Sin Kyu; Serpico, Pasquale Dario

    2014-01-01

    In the light of the new IceCube data on the (yet unidentified) astrophysical neutrino flux in the PeV and sub-PeV range, we present an update on the status of decaying dark matter interpretation of the events. In particular, we develop further the angular distribution analysis and discuss the perspectives for diagnostics. By performing various statistical tests (maximum likelihood, Kolmogorov-Smirnov and Anderson-Darling tests) we conclude that currently the data show a mild preference (below the two sigma level) for the angular distribution expected from dark matter decay vs. the isotropic distribution foreseen for a conventional astrophysical flux of extragalactic origin. Also, we briefly develop some general considerations on heavy dark matter model building and on the compatibility of the expected energy spectrum of decay products with the IceCube data, as well as with existing bounds from gamma-rays. Alternatively, assuming that the IceCube data originate from conventional astrophysical sources, we derive bounds on both decaying and annihilating dark matter for various final states. The lower limits on heavy dark matter lifetime improve by up to an order of magnitude with respect to existing constraints, definitively making these events—even if astrophysical in origin—an important tool for astroparticle physics studies

  12. What concentration of actinides can be packed into calcite? Hints from rare earth element (REE) composition

    International Nuclear Information System (INIS)

    Christiansen, J.; Stipp, S.L.S.; Waight, T.; Baker, J.A.

    2005-01-01

    Full text of publication follows: For reliable modelling of actinide mobility in the event of spent fuel repository failure, we need data describing the uptake capacity of the minerals likely to find themselves in the transport path. Calcite (CaCO 3 ) is a common secondary mineral in fractures and pore fillings, especially downstream from degrading concrete facilities, so it is a likely candidate for incorporation. Investigations made under ACTAF, a 5. Framework EURATOM integrated project, as well as some other research studies, have shown that actinides are successfully incorporated as substituting ions within the calcite mineral structure. The question remaining, is how much can calcite take up. Geologists routinely use relative concentrations of rare Earth elements (REE's), the lanthanides, for interpreting rock genesis and history. One can also adopt them as analogues for the radioactive elements because their f-orbital electron configuration makes them behave very much like actinides. We collected and analysed a suite of 70 calcite samples from a great number of possible formation environments, geological ages and geographical locations, for the purpose of finding the range and maximum of total f-orbital substitution possible in calcite, under natural conditions. We analysed them using Multi-Collector Inductively Coupled Plasma Mass Spectrometry (MC-ICP-MS). The maximum concentration found was about 5 x 10 -3 mole/kg total REE in a sample that had a geological history of formation where REE fluids played a role. Over the whole suite, total REE ranged from less than 10 -4 moles/kg for limestone samples formed from biogenic calcite where REE-enriched fluids would have played a negligible role. Thus, in natural calcite, REE's are present and all evidence points to a structural incorporation within the mineral rather than as a separate REE-rich phase. These data compare favourably with mole fractions from calcite grown synthetically, where as much as 6 x 10 -3 moles Eu were incorporated per kg calcite. These results give confidence that if the concentrations are low and calcite formation is favoured, migrating actinides will be incorporated into calcite, to be immobilised there, as long as solution conditions do not favour its dissolution. (authors)

  13. Supportive hints in a digital learning environment : Effects on students' motivation

    NARCIS (Netherlands)

    ter Beek, Marlies; Brummer, Leonie; Donker-Bergstra, Anouk; Opdenakker, Marie-christine

    2017-01-01

    Reading skills are developed across the lifespan. However, little is known about the development of reading comprehension skills and materials in secondary education, where students do not learn to read, but read to learn. When students read informational textbooks, domain knowledge (e.g., about

  14. The close of the year brings a hint that prices may be coming down

    International Nuclear Information System (INIS)

    Anon.

    1997-01-01

    A summary of financial data for the uranium spot market in December 1996 is provided. Price ranges for the restricted and unrestricted markets, conversion, and separative work are listed, and total market volume and new contracts are noted. Transactions made are briefly described. Deals made and pending in the spot concentrates, medium and long-term, conversion, and markets are listed for U.S. and non-U.S. buyers

  15. Electric field fluctuations in liquid tellurium alloys a hint to bond character

    NARCIS (Netherlands)

    Paulick, C.A.; Brinkmann, R.; Elwenspoek, Michael Curt; von Hartrott, M.; Kiehl, M.; Maxim, P.; Quitmann, D.

    1985-01-01

    Atomic scale electric field fluctuations in liquid tellurium alloys are detected as they induce nuclear spin relaxation rate RQ in noble gas impurity atoms, via quadrupolar interaction. Results for Xe in liquid Ag, Ga, In, Tl, Ge, Sn---Te alloys are discussed, assuming that bonding in these alloys

  16. Smartphone Ownership Among US Adult Cigarette Smokers: 2014 Health Information National Trends Survey (HINTS) Data

    OpenAIRE

    Heffner, Jaimee L; Mull, Kristin E

    2017-01-01

    Background Despite increasing interest in smartphone apps as a platform for delivery of tobacco cessation interventions, no previous studies have evaluated the prevalence and characteristics of smokers who can access smartphone-delivered interventions. Objective To guide treatment development in this new platform and to evaluate disparities in access to smartphone-delivered interventions, we examined associations of smartphone ownership with demographics, tobacco use and thoughts about quitti...

  17. Cutaneous melanoma: hints from occupational risks by anatomic site in Swedish men

    Science.gov (United States)

    Perez-Gomez, B; Pollan, M; Gustavsson, P; Plato, N; Aragones, N; Lopez-Abente, G

    2004-01-01

    Aims: To improve knowledge of the epidemiology of melanoma by comparing occupational risks of cutaneous melanoma (CM) by anatomic site in Swedish workers. Methods: Male workers employed in 1970 and living in the country in 1960 were followed up from 1971 to 1989 using the Swedish Registers of Death and Cancer. A more specifically exposed subcohort included men reporting the same occupation in 1960 and 1970. For each location, occupational risk ratios (RRs) were extracted from Poisson regression models adjusted by age, period, town size, and geographical area. To diminish the influence of socioeconomic factors, intrasector analyses, comparing only jobs belonging to the same occupational sector, were performed. Risk patterns for different locations were compared. Results: High RRs for different sites were found among workers exposed to UV sources (dentists, physiotherapists, and lithographers), and sun exposed workers (harbour masters, and lighthouse/related work). Risk excesses were seen in fur tailors, tanners/fur dressers, patternmakers/cutters, electrical fitters/wiremen, telephone/telegraph installers/repairmen, and some glass/pottery/tile workers. Results for lower and upper limbs were significantly correlated but somewhat independent of those found in thorax, the most frequent location. Correlation between head/neck and thorax was moderate. Specific risk excesses were found for rolling mill workers in head/neck, for chimney sweeps in upper limbs, and for aircraft pilots/navigators/flight engineers in lower limbs. Conclusions: High RRs in the trunk among occupations with UV exposure from artificial sources suggest an effect not restricted to exposed sites. An unusual distribution of cases and RRs in chimney sweeps, rolling-mill, or glass/pottery/tile workers suggests local effects of exposures. The not previously reported risk excess in this job and in fur related processes, and the RR in electrical fitters and telephone/telegraph installers deserve further investigation. Disparities between locations, as RRs in thorax and limbs, may reflect differences in aetiological mechanisms. PMID:14739377

  18. Sünnitades "Ema ja tütart" / Anna Hints

    Index Scriptorium Estoniae

    Hints, Anna, 1982-

    2010-01-01

    Tartu sünnitusmajale Toomemäel, naise eluringile ja põlvkondade järjepidevusele pühendatud "Ema ja tütar" kui koha, heli, foto ja rituaalse tegevuse koostoimel sündinud autori tajuvõrgustikku dekodeeriv pärimusliku ja isikliku taustaga kunstitöö

  19. Bulk Comptonization: new hints from the luminous blazar 4C+25.05

    Science.gov (United States)

    Kammoun, E. S.; Nardini, E.; Risaliti, G.; Ghisellini, G.; Behar, E.; Celotti, A.

    2018-01-01

    Blazars are often characterized by a spectral break at soft X-rays, whose origin is still debated. While most sources show a flattening, some exhibit a blackbody-like soft excess with temperatures of the order of ∼0.1 keV, similar to low-luminosity, non-jetted Seyferts. Here, we present the analysis of the simultaneous XMM-Newton and NuSTAR observations of the luminous flat-spectrum radio quasar 4C+25.05 (z = 2.368). The observed 0.3-30 keV spectrum is best described by the sum of a hard X-ray power law (Γ = 1.38_{-0.03}^{+0.05}) and a soft component, approximated by a blackbody with kT_BB = 0.66_{-0.04}^{+0.05} keV (rest frame). If the spectrum of 4C+25.05 is interpreted in the context of bulk Comptonization by cold electrons of broad-line region photons emitted in the direction of the jet, such an unusual temperature implies a bulk Lorentz factor of the jet of Γbulk ∼ 11.7. Bulk Comptonization is expected to be ubiquitous on physical grounds, yet no clear signature of it has been found so far, possibly due to its transient nature and the lack of high-quality, broad-band X-ray spectra.

  20. Heterogeneous rates for birth defects in Latin America: hints on causality.

    Science.gov (United States)

    Lopez-Camelo, J S; Orioli, I M

    1996-01-01

    The aim of this work was to disclose risk factors associated with birth defects which were heterogeneously distributed in the different geographic regions sampled by the Latin American Collaborative Study of Congenital Malformations (ECLAMC). The material included 2,159,065 hospital births, delivered in the 1967-1989 period in 24 geographic regions of Latin America. Birth defect types with 50 case-control pairs or more were analyzed. A risk factor was defined as that available variable with differential geographic rates, correlated with those of a given birth defect type. Identified factors were tested by case-control multivariate logistic regression to confirm their role in the occurrence of the defect. Altitude and maternal acute illness during first trimester of pregnancy, named influenza, were risk factors for microtia. Prenatal drug exposure, mainly sex hormones, were connected with the occurrence of hypospadias in low frequency areas, while Native ancestry was a "protective" factor in the same regions. Acute (influenza), and chronic (epilepsy and syphilis) maternal illness during first trimester of pregnancy and gravidity higher than four were risk factors for cleft lip. The independence of these variables from maternal age suggested that low maternal socioeconomic level could explain the high birth defect order and, perhaps, syphilis in mothers. Postaxial polydactyly was associated with parental consanguinity, as well as Afro-American ancestry, suggesting genetic heterogeneity.

  1. On a Fairy's Wing: Hints of Fitzgerald in Hemingway's "The Butterfly and the Tank"

    OpenAIRE

    Plath, James

    2008-01-01

    Lorsque, encore en France, Ernest Hemingway compose « The Butterfly and the Tank », le souvenir de conduite outrancière des Fitzgerald à Paris et à Juan-les-Pins est certainement présent dans son esprit. Le nombre d’allusions à Scott et Zelda sont trop soulignées pour qu’il en soit autrement. La structure de cette nouvelle, avec un Hemingway qui tient le rôle habituel de correspondant aguerri confirme ce postulat.Hemingway s’est souvent montré critique par rapport aux lamentations de Fitzgera...

  2. Õun. Minu kõige mõttetum ost : [jutt] / Anna Hints

    Index Scriptorium Estoniae

    Hints, Anna

    2006-01-01

    Sisu: Juuli 2004 ; August 2004 ; September 2004 ; September 2004, kuskil keskel ; September 2004, lõpus ; Oktoober 2004, 1. nädal ; Oktoober 2004, 2. nädal ; Oktoober 2004, 3. nädala alguses ; Oktoober 2004, 3. nädala lõpupoole ; Oktoober 2004, 4. nädal ; November 2004, 1. nädal ; November 2004, lõpp ; Jaanuar 2005, täna

  3. SPINS OF LARGE ASTEROIDS: A HINT OF A PRIMORDIAL DISTRIBUTION IN THEIR SPIN RATES

    Energy Technology Data Exchange (ETDEWEB)

    Steinberg, Elad; Sari, Re’em [The Hebrew University of Jerusalem, Jerusalem (Israel)

    2015-04-15

    The Asteroid Belt and the Kuiper Belt are relics from the formation of our solar system. Understanding the size and spin distribution of the two belts is crucial for a deeper understanding of the formation of our solar system and the dynamical processes that govern it. In this paper, we investigate the effect of collisions on the evolution of the spin distribution of asteroids and KBOs. We find that the power law nature of the impactors’ size distribution leads to a Lévy distribution of the spin rates. This results in a power law tail in the spin distribution, in stark contrast to the usually quoted Maxwellian distribution. We show that for bodies larger than 10 km, collisions alone lead to spin rates peaking at 0.15–0.5 revolutions per day. Comparing that to the observed spin rates of large asteroids (R > 50 km), we find that the spins of large asteroids, peaking at ∼1–2 revolutions per day, are dominated by a primordial component that reflects the formation mechanism of the asteroids. Similarly, the Kuiper Belt has undergone virtually no collisional spin evolution, assuming current densities. Collisions contribute a spin rate of ∼0.01 revolutions per day, thus the observed fast spin rates of KBOs are also primordial in nature.

  4. Hints for Small Disks around Very Low Mass Stars and Brown Dwarfs

    Energy Technology Data Exchange (ETDEWEB)

    Hendler, Nathanial P.; Mulders, Gijs D.; Pascucci, Ilaria [Lunar and Planetary Laboratory, The University of Arizona, Tucson, AZ 85721 (United States); Greenwood, Aaron; Kamp, Inga [Kapteyn Astronomical Institute, University of Groningen, Postbus 800, 9700 AV Groningen (Netherlands); Henning, Thomas [Max Planck Institute for Astronomy, Konigstuhl 17, D-69117 Heidelberg (Germany); Ménard, François [Univ. Grenoble Alpes, CNRS, IPAG, F-38000 Grenoble (France); Dent, William R. F. [Department of Engineering, Atacama Large Millimeter/submillimeter Array (ALMA) Santiago Central Offices, Alonso de Córdova 3107, Vitacura, Casilla 763 0355, Santiago (Chile); II, Neal J. Evans, E-mail: equant@lpl.arizona.edu [Department of Astronomy, The University of Texas at Austin, Austin, TX 78712 (United States)

    2017-06-01

    The properties of disks around brown dwarfs and very low mass stars (hereafter VLMOs) provide important boundary conditions on the process of planet formation and inform us about the numbers and masses of planets than can form in this regime. We use the Herschel Space Observatory PACS spectrometer to measure the continuum and [O i] 63 μ m line emission toward 11 VLMOs with known disks in the Taurus and Chamaeleon I star-forming regions. We fit radiative transfer models to the spectral energy distributions of these sources. Additionally, we carry out a grid of radiative transfer models run in a regime that connects the luminosity of our sources with brighter T Tauri stars. We find that VLMO disks with sizes 1.3–78 au, smaller than typical T Tauri disks, fit well the spectral energy distributions assuming that disk geometry and dust properties are stellar mass independent. Reducing the disk size increases the disk temperature, and we show that VLMOs do not follow previously derived disk temperature–stellar luminosity relationships if the disk outer radius scales with stellar mass. Only 2 out of 11 sources are detected in [O i] despite a better sensitivity than was achieved for T Tauri stars, suggesting that VLMO disks are underluminous. Using thermochemical models, we show that smaller disks can lead to the unexpected [O i] 63 μ m nondetections in our sample. The disk outer radius is an important factor in determining the gas and dust observables. Hence, spatially resolved observations with ALMA—to establish if and how disk radii scale with stellar mass—should be pursued further.

  5. Renewable energy technologies. Plant concepts, applications and practical hints; Regenerative Energietechnologien. Anlagenkonzepte, Anwendungen und Praxistipps

    Energy Technology Data Exchange (ETDEWEB)

    Theiss, Eric

    2008-07-01

    This textbook provides a comprehensive outline of renewable energy technologies, prototypes and innovations in technical facilities that are ready for the market. On the basis of current catalogues of technical rules, directives and guidelines, possible system configurations are outlined for each technology which are explained by means of examples, a system description, and a list of reference projects. There is also a glossary for the various technologies and a list of contact addresses. The textbook addresses architects, engineers, energy consultants, and students. (orig.)

  6. Hints of hybridizing Majorana fermions in a nanowire coupled to superconducting leads

    Science.gov (United States)

    Finck, A. D. K.; van Harlingen, D. J.; Mohseni, P. K.; Jung, K.; Li, X.

    2013-03-01

    It has been proposed that a nanowire with strong spin-orbit coupling that is contacted with a conventional superconductor and subjected to a large magnetic field can be driven through a topological phase transition. In this regime, the two ends of the nanowire together host a pair of quasi-particles known as Majorana fermions (MFs). A key feature of MFs is that they are pinned to zero energy when the topological nanowire is long enough such that the wave functions of the two MFs do not overlap significantly, resulting in a zero bias anomaly (ZBA). It has been recently predicted that changes in external parameters can vary the wave function overlap and cause the MFs to hybridize in an oscillatory fashion. This would lead to a non-monotonic splitting or broadening of the ZBA and help distinguish MF transport signatures from a Kondo effect. Here, we present transport studies of an InAs nanowire contacted with niobium nitride leads in high magnetic fields. We observe a number of robust ZBAs that can persist for a wide range of back gate bias and magnetic field strength. Under certain conditions, we find that the height and width of the ZBA can oscillate with back gate bias or magnetic field. This work was supported by Microsoft Project Q.

  7. Association of tinnitus and electromagnetic hypersensitivity: hints for a shared pathophysiology?

    Directory of Open Access Journals (Sweden)

    Michael Landgrebe

    Full Text Available BACKGROUND: Tinnitus is a frequent condition with high morbidity and impairment in quality of life. The pathophysiology is still incompletely understood. Electromagnetic fields are discussed to be involved in the multi-factorial pathogenesis of tinnitus, but data proofing this relationship are very limited. Potential health hazards of electromagnetic fields (EMF have been under discussion for long. Especially, individuals claiming themselves to be electromagnetic hypersensitive suffer from a variety of unspecific symptoms, which they attribute to EMF-exposure. The aim of the study was to elucidate the relationship between EMF-exposure, electromagnetic hypersensitivity and tinnitus using a case-control design. METHODOLOGY: Tinnitus occurrence and tinnitus severity were assessed by questionnaires in 89 electromagnetic hypersensitive patients and 107 controls matched for age-, gender, living surroundings and workplace. Using a logistic regression approach, potential risk factors for the development of tinnitus were evaluated. FINDINGS: Tinnitus was significantly more frequent in the electromagnetic hypersensitive group (50.72% vs. 17.5% whereas tinnitus duration and severity did not differ between groups. Electromagnetic hypersensitivity and tinnitus were independent risk factors for sleep disturbances. However, measures of individual EMF-exposure like e.g. cell phone use did not show any association with tinnitus. CONCLUSIONS: Our data indicate that tinnitus is associated with subjective electromagnetic hypersensitivity. An individual vulnerability probably due to an over activated cortical distress network seems to be responsible for, both, electromagnetic hypersensitivity and tinnitus. Hence, therapeutic efforts should focus on treatment strategies (e.g. cognitive behavioral therapy aiming at normalizing this dysfunctional distress network.

  8. Origin and evolution of retinoid isomerization machinery in vertebrate visual cycle: hint from jawless vertebrates.

    Science.gov (United States)

    Poliakov, Eugenia; Gubin, Alexander N; Stearn, Olivia; Li, Yan; Campos, Maria Mercedes; Gentleman, Susan; Rogozin, Igor B; Redmond, T Michael

    2012-01-01

    In order to maintain visual sensitivity at all light levels, the vertebrate eye possesses a mechanism to regenerate the visual pigment chromophore 11-cis retinal in the dark enzymatically, unlike in all other taxa, which rely on photoisomerization. This mechanism is termed the visual cycle and is localized to the retinal pigment epithelium (RPE), a support layer of the neural retina. Speculation has long revolved around whether more primitive chordates, such as tunicates and cephalochordates, anticipated this feature. The two key enzymes of the visual cycle are RPE65, the visual cycle all-trans retinyl ester isomerohydrolase, and lecithin:retinol acyltransferase (LRAT), which generates RPE65's substrate. We hypothesized that the origin of the vertebrate visual cycle is directly connected to an ancestral carotenoid oxygenase acquiring a new retinyl ester isomerohydrolase function. Our phylogenetic analyses of the RPE65/BCMO and N1pC/P60 (LRAT) superfamilies show that neither RPE65 nor LRAT orthologs occur in tunicates (Ciona) or cephalochordates (Branchiostoma), but occur in Petromyzon marinus (Sea Lamprey), a jawless vertebrate. The closest homologs to RPE65 in Ciona and Branchiostoma lacked predicted functionally diverged residues found in all authentic RPE65s, but lamprey RPE65 contained all of them. We cloned RPE65 and LRATb cDNAs from lamprey RPE and demonstrated appropriate enzymatic activities. We show that Ciona ß-carotene monooxygenase a (BCMOa) (previously annotated as an RPE65) has carotenoid oxygenase cleavage activity but not RPE65 activity. We verified the presence of RPE65 in lamprey RPE by immunofluorescence microscopy, immunoblot and mass spectrometry. On the basis of these data we conclude that the crucial transition from the typical carotenoid double bond cleavage functionality (BCMO) to the isomerohydrolase functionality (RPE65), coupled with the origin of LRAT, occurred subsequent to divergence of the more primitive chordates (tunicates, etc.) in the last common ancestor of the jawless and jawed vertebrates.

  9. Johannes Hint : ühe XX sajandi ausa mehe tragöödia / Holger Kaljulaid

    Index Scriptorium Estoniae

    Kaljulaid, Holger

    2006-01-01

    Desintegraatori juhi Johannes Hindi tegevusest ning temaga seotud kohtuprotsessist meedias avaldatud materjalide ja arhiividokumentide põhjal. Vt. samas väljavõtteid: Vladimir Georg Karassev-Orgusaare mõtteavaldusest 1982. aasta jaanuaris RL-i stuudios Pariisis; Johhannes Hindi sõnavõtust NSV Liidu Riikliku Plaanikomitee (Gosplan) kolleegiumil 10. II 1981 ja tema tööst "Viimaseid mõtteid inimkonnale", 1985; Aleksander Kaelase mõtteavaldusest aprillis 1955 Ameerika Hääle saates; Nikolai Baibakovi, Gosplani kunagise juhi (1965-85) 2000. a. märtsis antud intervjuust

  10. A 3.55 keV hint for decaying axion-like particle dark matter

    Energy Technology Data Exchange (ETDEWEB)

    Jaeckel, Joerg [Heidelberg Univ. (Germany). Inst. fuer Theoretische Physik; Redondo, Javier [Muenchen Univ. (Germany). Arnold Sommerfeld Center; Max-Planck-Institut fuer Physik, Muenchen (Germany); Ringwald, Andreas [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2014-02-15

    Recently, indications for an emission line at 3.55 keV have been found in the combined spectra of a large number of galaxy clusters and also in Andromeda. This line could not be identified with any known spectral line. It is tempting to speculate that it has its origin in the decay of a particle contributing all or part of the dark matter. In this note we want to point out that axion-like particles being all or part of the dark matter are an ideal candidate to produce such a feature. More importantly the parameter values necessary are quite feasible in extensions of the Standard Model based on string theory and could be linked up to a variety of other intriguing phenomena, which also potentially allow for new tests of this speculation.

  11. Are You a Gut Responder? Hints on Coping with an Irritable Bowel

    Science.gov (United States)

    ... problems to contend with. These can interfere with work or school and social functions both in obvious and subtle ways – including ... a better understanding of your own gut-brain connections, ask your doctor to suggest a mental health ... Read More Personal Relationships ...

  12. Hints about Dark, Light-Bending Matter in the Distant Universe

    Science.gov (United States)

    1997-07-01

    New infrared observations of a gravitational lens About 20 cases of gravitationally lensed (GL) quasars are known. This special physical effect, also known as a cosmic mirage, occurs when the rays of light of a distant quasar on their way to us pass near a massive object, for instance a galaxy. As a result, two or more images of the same quasar will be seen near each other. This phenomenon is described in more detail in the Appendix. A new study by a group of three European astronomers, headed by Frederic Courbin ( Institut d'Astrophysique, Universite de Liege, Belgium, and Observatoire de Paris-Meudon, France) [1], has led to the discovery of the object responsible for the double images of a remote quasar in the gravitational lens HE 1104-1805 . The investigation is based on infrared observations at the ESO La Silla Observatory in Chile and the `lensing system' turns out to be a distant, massive galaxy. Nevertheless, the geometry of the object is unusual and an additional gravitational lens of `dark' (invisible) matter may possibly be involved. This gravitational lens is also particularly well suited for future cosmological studies that aim at the determination of the Hubble constant and the expansion rate of the Universe. A new and detailed study of gravitational lenses It is rare among the relatively few, confirmed cases of gravitational lensing in the distant Universe, that the distribution of matter in the lensing system is well known. However, it is exactly this information that is needed to derive cosmological parameters by means of photometric monitoring of the brightness of the individual images in a gravitational lens [2]. The three astronomers have therefore undertaken a detailed study of some previously known gravitational lenses (or good candidate objects) with the primary aim to detect and map the associated lensing matter (refered to as the gravitational deflector or lensing object ). This is observationally quite difficult and time-consuming since the huge masses responsible for the gravitational bending of light are almost always located at very large distances from us. Thus they are quite faint and can only be observed with large telescopes and state-of-the-art equipment. Moreover, the faint images of lensing objects are located between the much brighter quasar images they lens. This makes the discovery of a lensing object and the recording of its image a most challenging task. The advantage of infrared observations The image of a remote galaxy is usually very faint at visible wavelengths, but it is brighter in the infra-red part of the spectrum. This is because the wavelength of maximum intensity in the spectrum of a rapidly receding, distant galaxy (a composite of the spectra of the stars of which it consists) is redshifted from the visual into the infrared region of the spectrum. For instance, galaxies with redshifts around z = 1 [3] are best observed in the J -band near the near-infrared wavelength of 1.25 microns (about twice that of red light), while the images of galaxies with even higher redshifts and velocities are better recorded in the 2.2 micron K -band. The present search for gravitational deflectors is therefore conducted in the infrared spectral region, using the ESO/MPI 2.2-m telescope and the IR detector IRAC 2b . Such a survey has the further advantage of revealing, if present, additional lensed images of the quasars, that may be heavily obscured by intervening dust, for example by the dust contained in the lensing galaxy. A new and powerful image combination/deconvolution algorithm These investigations have always been difficult because of the small angular separations in such lensed objects, of the order of one arcsecond, or even less in many cases. This corresponds to the image-smearing (seeing) effects introduced by atmospheric turbulence under common ground-based observing conditions. Detailed observations of such objects are therefore normally best made from space-based observatories, like the Hubble Space Telescope (HST). However, an alternative method of obtaining high-resolution images is to combine numerous exposures of the same object in an optimised way; this allows to `eliminate' most of the image degradation caused by atmospheric effects. New and powerful software for this procedure has recently been developed at the Astrophysical Institute in Liege, cf. http://vela.astro.ulg.ac.be/imaproc. The new algorithm allows to treat (`deconvolve') simultaneously a large number of exposures - especially in the infrared - and yields high-resolution, combined images of the celestial objects on which precise brightness and positional measurements can be performed. Detection of the lensing galaxy in HE 1104-1805 During the present programme, the astronomers recently observed HE 1104-1805 , a gravitational lens with a doubly imaged quasar with a redshift of z = 2.316 that was discovered in 1993 at the La Silla Observatory. Observations in 1995, made in the I -waveband (0.9 micron) under poor seeing conditions, showed a very faint feature between the quasar images but the observations did not allow to ascertain the nature of this object. Caption to ESO PR Photo 21/97 [JPEG, 55k] New infrared images were obtained during the night of April 14-15, 1997. They were then processed with the new software and the resulting, detailed images with high-angular resolution, 0.27 arcsec, now show very clearly the lensing object, a remote, elliptical galaxy, between the quasar images. The image displayed in ESO Press Photo 21/97 was obtained in the near-infrared J-band, where the lensing galaxy in HE 1104-1805 is quite faint, but still well visible and measurable after `deconvolution'. The observed, infrared colour, i.e. the difference in brightness of its image in the J- and K-bands (the (J-K) index ), is compatible with that of a high-redshift elliptical galaxy, at a distance corresponding to a redshift somewhere between z = 1 and z = 1.8. The brightest of the two quasar images (`A'; the upper one in ESO PR Photo 21/97) shows absorption lines in its spectrum which have been redshifted at z = 1.66. Since the lensing galaxy is situated at a small angular distance from this component, it is quite likely that these spectral lines are produced by this galaxy. Thus, the gravitational deflector in HE 1104-1805 is most probably an elliptical galaxy at redshift z = 1.66. This corresponds to a recession velocity of about 200,000 km/sec and a distance that, depending on the adopted Hubble relation, is of the order of 6,000 - 9,000 million light-years. Since this galaxy is comparatively bright in the infrared, this may be checked in the near future by taking an infrared spectrum, for example with the future IR instrument of the ESO New Technology Telescope, SOFI, cf. ESO Press Photo 17/97. Continued studies of HE 1104-1805 This gravitational lens is known to show brightness variations with time. It is therefore a good candidate for continued photometric monitoring which may possibly yield a new and independent determination of the Hubble constant [2], as this was recently done for another gravitational lens, PG 1115+080 [4]. If the lensing galaxy is actually located at redshift z = 1.66, then the time delay expected for brightness variations of the two lensed quasar images is of the order of 3 to 4 years, depending on the model. This should be easily measurable. A `Dark Lens' in HE 1104-1805? The observed geometry of HE 1104-1805 is somewhat surprising, since current lens models predict that the position of the deflector, as seen in the sky, is closer to the fainter quasar image than to the brighter one; here the contrary is the case. This would suggest that the distribution of the lensing matter is more complex than that of a single elliptical galaxy. In addition, the brightness of the lensing galaxy in the K-band is somewhat too high for a normal one. This may indicate the presence of a more massive object, for example a cluster of galaxies. This may not be the case, though, since the present, very deep observations would have allowed the detection of any normal cluster of galaxies between us and the quasar whose light is being split by the lens. An interesting question is therefore: do we `see' the effects of a lens of dark matter in HE 1104-1805? Only future observations, for instance with the ESO Very Large Telescope (VLT) , will tell. Where to find additional information More details about the image deconvolution techniques used for this investigation is available at the WWW pages of the Liege group. Information about another gravitational-lens related discovery by astronomers at the Institut d'Astrophysique in Liege have been reported in ESO Press Release 04/96 (9 February 1996). Notes: [1] The group consists of Frederic Courbin (Institut d'Astrophysique, Universite de Liege, Belgium, and Observatoire de Paris-Meudon, France) and Pierre Magain (Institut d'Astrophysique, Universite de Liege, Belgium) and Chris Lidman (ESO). [2] The careful observation of similar, but time-shifted brightness variations of the individual images of a quasar in a gravitational lens may sometimes lead to a determination of the distance to the lensing object (normally a distant galaxy). This is because the measured time delay of such variations (from some months to several years), from the known speed of light, will provide a direct indication of the difference in the length of the two light paths, expressed in kilometres. If moreover the overall distribution of the matter that causes the lensing effect is known (from observations of the shape of the lens) and thus the relative geometry of the lensing system and the light paths, it is then possible to estimate the absolute size of the system. When this is compared with its angular size (as seen in the sky on direct images), the true distance to the lensing object can be found. Dividing this distance with the measured recession velocity (along the line-of-sight), finally gives an independent value of the expansion rate of the Universe, the famous Hubble constant . [3] In astronomy, the redshift denotes the fraction by which the lines in the spectrum of an object are shifted towards longer wavelengths. The observed redshift of a distant galaxy or quasar gives a direct estimate of the apparent recession velocity as caused by the universal expansion. Since the expansion rate increases with the distance, the velocity is itself a function (the Hubble relation) of the distance to the object. A redshift of z = 1 corresponds to a recession velocity of 180,000 km/sec; z = 2 to 214,300 km/sec, z = 3 to 233,300 km/sec, and z = 4 to 245,500 km/sec; the non-proportionality is a relativistic effect. [4] Detailed information about PG 1115+080 may be found in the scientific papers by Schechter et al. (1997, ApJ, 475, L85) and Courbin et al. (1997, SISSA preprint astro-ph/9705093, A&A Letters, in press). Appendix: What is a gravitational lens? The physical principle behind a gravitational lens (also known as a cosmic mirage ) has been known since 1916 as a consequence of Einstein's General Relativity Theory. The gravitational field of a massive object curves the local geometry of the Universe, so light rays passing close to the object are also curved (in the same way as a `straight line' on the surface of the Earth is necessarily curved because of the curvature of the Earth's surface). This effect was first observed by astronomers in 1919 during a total solar eclipse. Accurate positional measurements of stars seen in the dark sky near the eclipsed Sun indicated an apparent displacement in the direction opposite to the Sun, about as much as predicted by the theory. The effect was obviously due to the gravitational attraction of the stellar photons when they passed near the Sun on their way to us. This was a direct confirmation of a new phenomenon and represented a milestone in physics. In the 1930's, astronomer Fritz Zwicky (1898 - 1974), of Swiss nationality and working at the Mount Wilson Observatory in California, realised that the same effect may also happen far out in space where galaxies and large galaxy clusters may be sufficiently compact and massive to bend the light from even more distant objects. However, it was only five decades later, in 1979, that his ideas were observationally confirmed when the first example of a cosmic mirage was discovered. In this connection, it is of particular interest, that this gravitational lensing effect may not only result in double or multiple images of the same object, but also that the intensities of these images increase significantly, just as it is the case with an ordinary optical lens. Distant galaxies, galaxy clusters, etc. may thereby act as natural telescopes which allow us to observe objects that would otherwise have been too faint to be detected with currently available astronomical telescopes. How to obtain ESO Press Information ESO Press Information is made available on the World-Wide Web (URL: http://www.eso.org../). ESO Press Photos may be reproduced, if credit is given to the European Southern Observatory.

  13. Eesti identiteedi kasv ja kasvatus 2006. aastal - Kumust Brotzeni / Mati Hint

    Index Scriptorium Estoniae

    Hint, Mati, 1937-

    2006-01-01

    Tallinna Ülikooli emeriitprofessori loetletud tippsündmused Eesti kunsti ja ajaloo valdkonnas 2006. a. - Kumu Kunstimuuseumi avamine, Kristjan ja Paul Raua näitus Kumus ning Riias tegutsenud baltisaksa kultuuriloolase Johann Christoph Brotze joonistuste kogumiku "Johann Christoph Brotze. Estonica." Koostanud Ants Hein, Ivar Leimus, Raimo Pullat, Ants Viires. Estopol OÜ 2006, ilmumine Tallinnas, peatoimetaja Raimo Pullat. Pikemalt eesti nüüdisaegsest kunstist Kumus ja rahvuslikust identiteedist

  14. Ignoring Memory Hints: The Stubborn Influence of Environmental Cues on Recognition Memory

    Science.gov (United States)

    Selmeczy, Diana; Dobbins, Ian G.

    2017-01-01

    Recognition judgments can benefit from the use of environmental cues that signal the general likelihood of encountering familiar versus unfamiliar stimuli. While incorporating such cues is often adaptive, there are circumstances (e.g., eyewitness testimony) in which observers should fully ignore environmental cues in order to preserve memory…

  15. Temporomandibular joint disorder complaints in tinnitus: further hints for a putative tinnitus subtype.

    Directory of Open Access Journals (Sweden)

    Veronika Vielsmeier

    Full Text Available OBJECTIVE: Tinnitus is considered to be highly heterogeneous with respect to its etiology, its comorbidities and the response to specific interventions. Subtyping is recommended, but it remains to be determined which criteria are useful, since it has not yet been clearly demonstrated whether and to which extent etiologic factors, comorbid states and interventional response are related to each other and are thus applicable for subtyping tinnitus. Analyzing the Tinnitus Research Initiative Database we differentiated patients according to presence or absence of comorbid temporomandibular joint (TMJ disorder complaints and compared the two groups with respect to etiologic factors. METHODS: 1204 Tinnitus patients from the Tinnitus Research Initiative (TRI Database with and without subjective TMJ complaints were compared with respect to demographic, tinnitus and audiological characteristics, questionnaires, and numeric ratings. Data were analysed according to a predefined statistical analysis plan. RESULTS: Tinnitus patients with TMJ complaints (22% of the whole group were significantly younger, had a lower age at tinnitus onset, and were more frequently female. They could modulate or mask their tinnitus more frequently by somatic maneuvers and by music or sound stimulation. Groups did not significantly differ for tinnitus duration, type of onset (gradual/abrupt, onset related events (whiplash etc., character (pulsatile or not, hyperacusis, hearing impairment, tinnitus distress, depression, quality of life and subjective ratings (loudness etc.. CONCLUSION: Replicating previous work in tinnitus patients with TMJ complaints, classical risk factors for tinnitus like older age and male gender are less relevant in tinnitus patients with TMJ complaints. By demonstrating group differences for modulation of tinnitus by movements and sounds our data further support the notion that tinnitus with TMJ complaints represents a subgroup of tinnitus with clinical features that are highly relevant for specific therapeutic management.

  16. Melatonin, Noncoding RNAs, Messenger RNA Stability and Epigenetics—Evidence, Hints, Gaps and Perspectives

    Science.gov (United States)

    Hardeland, Rüdiger

    2014-01-01

    Melatonin is a highly pleiotropic regulator molecule, which influences numerous functions in almost every organ and, thus, up- or down-regulates many genes, frequently in a circadian manner. Our understanding of the mechanisms controlling gene expression is actually now expanding to a previously unforeseen extent. In addition to classic actions of transcription factors, gene expression is induced, suppressed or modulated by a number of RNAs and proteins, such as miRNAs, lncRNAs, piRNAs, antisense transcripts, deadenylases, DNA methyltransferases, histone methylation complexes, histone demethylases, histone acetyltransferases and histone deacetylases. Direct or indirect evidence for involvement of melatonin in this network of players has originated in different fields, including studies on central and peripheral circadian oscillators, shift work, cancer, inflammation, oxidative stress, aging, energy expenditure/obesity, diabetes type 2, neuropsychiatric disorders, and neurogenesis. Some of the novel modulators have also been shown to participate in the control of melatonin biosynthesis and melatonin receptor expression. Future work will need to augment the body of evidence on direct epigenetic actions of melatonin and to systematically investigate its role within the network of oscillating epigenetic factors. Moreover, it will be necessary to discriminate between effects observed under conditions of well-operating and deregulated circadian clocks, and to explore the possibilities of correcting epigenetic malprogramming by melatonin. PMID:25310649

  17. Hints About Some Baseful but Indispensable Elements in Speech Recognition and Reconstruction

    Directory of Open Access Journals (Sweden)

    Mihaela Costin

    2002-07-01

    Full Text Available The cochlear implant (CI is a device used to reconstruct the hearing capabilities of a person diagnosed with total cophosis. This impairment may occur after some accidents, chemotherapy etc., the person still having an intact hearing nerve. The cochlear implant has two parts: a programmable, external part, the Digital Signal Processing (DSP device which process and transform the speech signal, and another surgically implanted part, with a certain number of electrodes (depending on brand used to stimulate the hearing nerve. The speech signal is fully processed in the DSP external device resulting the ``coded'' information on speech. This is modulated with the support of the fundamental frequency F0 and the energy impulses are inductively sent to the hearing nerve. The correct detection of this frequency is very important, determining the manner of hearing and making the difference between a "computer'' voice and a natural one. The results are applicable not only in the medical domain, but also in the Romanian speech synthesis.

  18. Thermoelectric Properties of TI – Doped SnSe: A Hint of Phononic Structure

    Czech Academy of Sciences Publication Activity Database

    Kucek, V.; Plecháček, T.; Janíček, P.; Ruleová, P.; Beneš, L.; Navrátil, Jiří; Drašar, Č.

    2016-01-01

    Roč. 45, č. 6 (2016), s. 2943-2949 ISSN 0361-5235 R&D Projects: GA ČR(CZ) GA16-07711S Institutional support: RVO:61389013 Keywords : semiconductors * chalcogenides * X-ray diffraction Subject RIV: CA - Inorganic Chemistry Impact factor: 1.579, year: 2016

  19. The Physiological Roles of Amyloid-β Peptide Hint at New Ways to Treat Alzheimer's Disease

    Directory of Open Access Journals (Sweden)

    Holly M. Brothers

    2018-04-01

    Full Text Available Amyloid-ß (Aß is best known as the misfolded peptide that is involved in the pathogenesis of Alzheimer's disease (AD, and it is currently the primary therapeutic target in attempts to arrest the course of this disease. This notoriety has overshadowed evidence that Aß serves several important physiological functions. Aß is present throughout the lifespan, it has been found in all vertebrates examined thus far, and its molecular sequence shows a high degree of conservation. These features are typical of a factor that contributes significantly to biological fitness, and this suggestion has been supported by evidence of functions that are beneficial for the brain. The putative roles of Aß include protecting the body from infections, repairing leaks in the blood-brain barrier, promoting recovery from injury, and regulating synaptic function. Evidence for these beneficial roles comes from in vitro and in vivo studies, which have shown that the cellular production of Aß rapidly increases in response to a physiological challenge and often diminishes upon recovery. These roles are further supported by the adverse outcomes of clinical trials that have attempted to deplete Aß in order to treat AD. We suggest that anti-Aß therapies will produce fewer adverse effects if the known triggers of Aß deposition (e.g., pathogens, hypertension, and diabetes are addressed first.

  20. Breastfeeding: Hints to Help You Get Off to a Good Start

    Science.gov (United States)

    ... Kids and Teens Pregnancy and Childbirth Women Men Seniors Your Health Resources Healthcare Management End-of-Life Issues Insurance & Bills Self Care Working With Your Doctor Drugs, Procedures & Devices Over-the- ...

  1. Kaire Kemp-Tishler : harmoonia moodsa ja vana vahel / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Eramu sisekujundus. Sisearhitekt Kaire Kemp-Tishler, tema kommentaarid. Arhitekt Vahur Sova. Kamina sepised tegi Heigo Jelle. Trepihallis Tiit Pääsukese maal "Orasnzh". Ill.: I ja II korruse plaan, 14 värv. vaadet

  2. Kaire Kemp-Tishler: "Igatsen luua midagi kole-ilusat" / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Kaire Kemp-Tishler (sünd. 1964) kodu sisekujunduse projekteerimisest, tasakaalust sisearhitektuuris, oma kodust. Kaire Kemp-Tishlerist, tema tehtud tööde loetelu. 1998. aastast teeb K. Kemp-Tishler koostööd Ea Andlaga, kellega koos asutas 2001. a. OÜ sisearhitektuuribüroo ArtAku. Ill.: K. Kemp-Tishleri värv. portree

  3. Developing an Intelligent Tutoring System That Has Automatically Generated Hints and Summarization for Algebra and Geometry

    Science.gov (United States)

    Li, Yatao; Zhao, Ke; Xu, Wei

    2015-01-01

    Intelligent tutoring systems (ITSs), which provide step-by-step guidance to students in problem-solving activities, have been shown to enhance student learning in a range of domains. However, they tend to be pre-established and cannot supply the tutoring function immediately from the diverse mathematical questions. The MITSAS (multiagent…

  4. Issue Brief #2: Metrics for Improving Cost Accountability (Hint: Not More Detailed Cost Accounting...)

    Science.gov (United States)

    Delta Project on Postsecondary Education Costs, Productivity and Accountability, 2009

    2009-01-01

    Most fiscal reporting focuses on revenues (whether or not they go to core purposes), tuition and fees, and financial aid. "How" the money is spent is something that remains shrouded in too much mystery. Several national efforts to address this problem have largely come to naught--probably because those common methodologies are simultaneously not…

  5. Evidence of earlier thyroid dysfunction in newly diagnosed oral lichen planus patients: a hint for endocrinologists.

    Science.gov (United States)

    Arduino, Paolo G; Karimi, Dora; Tirone, Federico; Sciannameo, Veronica; Ricceri, Fulvio; Cabras, Marco; Gambino, Alessio; Conrotto, Davide; Salzano, Stefano; Carbone, Mario; Broccoletti, Roberto

    2017-11-01

    The association between oral lichen planus (OLP) and hypothyroidism has been debated with conflicting results: some authors detected a statistically significant association between these two, while others did not confirm it. The aim of this study was to evaluate the thyroid status in patients with newly diagnosed OLP to test the null hypothesis that thyroid disease is not associated with an increased incidence of oral lesions, with a prospective case-control approach. A total of 549 patients have been evaluated, of whom 355 were female. Odds ratio (OR) and 95% confidence intervals (CIs) were obtained. Patients suffering from thyroid diseases were associated with an almost 3-fold increased odds of having OLP (OR 2.85, 95% CI: 1.65-4.94), after adjusting this analysis for age, gender, body mass index, smoking status, diabetes, hypertension and hepatitis C infection. It would be appropriate to further investigate the possible concomitance of OLP among patients with thyroid disorder; endocrinologists should be aware of this association, especially because OLP is considered a potentially malignant oral disorder. © 2017 The authors.

  6. An overview of MR arthrography with emphasis on the current technique and applicational hints and tips

    Energy Technology Data Exchange (ETDEWEB)

    Sahin, Guelden [Department of Radiology, Faculty of Medicine, Ankara University, Samanpazari, 06100 Ankara (Turkey)]. E-mail: gsahin@medicine.ankara.edu.tr; Demirtas, Mehmet [Department of Hand Surgery, Faculty of Medicine, Ankara University, Samanpazari, 06100 Ankara (Turkey)

    2006-06-15

    Magnetic resonance (MR) arthrography has been investigated in every major peripheral joint of the body, and has been proven to be effective in determining the integrity of intraarticular ligamentous and fibrocartilaginous structures and in the detection or assessment of osteochondral lesions and loose bodies in selected cases. Several methods could be used to create arthrogram effect during MR imaging, however, direct MR arthrography using diluted gadolinium as the contrast agent is the most commonly used technique and is the most reliable of all. MR arthrography is useful for demonstrating labrocapsular-ligamentous abnormalities and distinguishing partial thickness rotator cuff tears from focal full thickness tears in the shoulder, identifying or excluding recurrent tears following meniscal operations in the knee, demonstrating perforations of the triangular fibrocartilage complex (TFCC) and ligaments in the wrist, showing labral tears in the hip, diagnosing ligament tears in the ankle and identifying osteochondral lesions or loose bodies in any of the aforementioned joints. In this article, an overview of techniques of MR arthrography is provided with emphasis on direct MR arthrography using diluted gadolinium as the contrast agent. The current applications of the technique in major peripheral joints are reviewed, with emphasis given to the shoulder joint where the role of this technique has become well established.

  7. A 3.55 keV hint for decaying axion-like particle dark matter

    International Nuclear Information System (INIS)

    Jaeckel, Joerg; Ringwald, Andreas

    2014-02-01

    Recently, indications for an emission line at 3.55 keV have been found in the combined spectra of a large number of galaxy clusters and also in Andromeda. This line could not be identified with any known spectral line. It is tempting to speculate that it has its origin in the decay of a particle contributing all or part of the dark matter. In this note we want to point out that axion-like particles being all or part of the dark matter are an ideal candidate to produce such a feature. More importantly the parameter values necessary are quite feasible in extensions of the Standard Model based on string theory and could be linked up to a variety of other intriguing phenomena, which also potentially allow for new tests of this speculation.

  8. Hints of Habitable Environments on Mars Challenge Our Studies of Mars-Analog Sites on Earth

    Science.gov (United States)

    desMarais, David J

    2009-01-01

    Life as we know it requires water with a chemical activity (alpha) >or approx.0.6 and sources of nutrients and useful energy. Some biota can survive even if favorable conditions occur only intermittently, but the minimum required frequency of occurrences is poorly understood. Recent discoveries have vindicated the Mars exploration strategy to follow the water. Mars Global Surveyor s Thermal Emission Spectrometer (TES) found coarse-grained hematite at Meridiani Planum. Opportunity rover confirmed this and also found evidence of ancient sulfate-rich playa lakes and near-surface groundwater. Elsewhere, TES found evidence of evaporitic halides in topographic depressions. But alpha might not have approached 0.6 in these evaporitic sulfate- and halide-bearing waters. Mars Express (MEX) and Mars Reconnaissance Orbiter (MRO) found extensive sulfate evaporites in Meridiani and Valles Marineris. MEX found phyllosilicates at several sites, most notably Mawrth Valles and Nili Fossae. MRO's CRISM near-IR mapper extended the known diversity and geographic distribution of phyllosilicates to include numerous Noachian craters. Phyllosilicates typically occur at the base of exposed ancient rock sections or in sediments in early Hesperian craters. It is uncertain whether the phyllosilicates developed in surface or subsurface aqueous environments and how long aqueous conditions persisted. Spirit rover found remarkably pure ferric sulfate, indicating oxidation and transport of Fe and S, perhaps in fumaroles or hot springs. Spirit also found opaline silica, consistent with hydrothermal activity. CRISM mapped extensive silica deposits in the Valles Marineris region, consistent with aqueous weathering and deposition. CRISM also found ultramafic rocks and magnesite at Nili Fossae, consistent with serpentinization, a process that can sustain habitable environments on Earth. The report of atmospheric methane implies subsurface aqueous conditions. A working hypothesis is that aqueous environments persisted in the near-subsurface for hundreds of millions of years and might exist even today. Studies of Mars-analog environments must better understand subsurface nonphotosynthetic ecosystems and their biosignatures in mafic and ultramafic terranes. Studies must determine minimum needs for water activity and energy and also establish survival limits when conditions that support active metabolism and propagation become progressively less frequent over time.

  9. Squint surgery in TED -- hints and fints, or why Graves' patients are difficult patients.

    Science.gov (United States)

    Nardi, M

    2009-01-01

    Endocrine ophthalmopathy is the most common cause of acute onset diplopia in middle aged or older individuals. Ocular muscle involvement is characterized by myositis followed by fibrosis: this causes a stiffness and a shortening of the muscles involved with restriction of ocular movements: so the impairment of rotation is due to a mechanical obstacle and not to a paresis. Prisms are rarely useful in relieving diplopia and the majority of symptomatic patients need squint surgery. Timing of surgery is very important and two considerations are to be kept in mind: first, the systemic disease must be in remission and the ocular deviation must be stable for at least six months; second, if more than one surgical procedure is needed for the ophthalmopathy, muscle surgery has its right place after orbital surgery and before lid surgery. Obviously dealing with restrictive disorders, surgery is based on weakening procedures of the affected muscles: identifying the affected muscles is of crucial importance and may be sometime difficult for the presence of misleading signs; great advances have been made in surgical technique with the development of adjustable sutures and of topical anesthesia. Prognosis is usually good with more than 80% of patients recovering a useful field of binocular single vision with one procedure and more than 90% with two or more procedures.

  10. Hints on the Broad Line Region Structure of Quasars at High and Low Luminosities

    Directory of Open Access Journals (Sweden)

    Marziani Paola

    2011-09-01

    Full Text Available Quasars show a considerable spectroscopic diversity. However, the variety of quasar spectra at low redshifts is non-random: a principal component analysis applied to large samples customarily identifies two main eigenvectors. In this contribution we show that the range of quasar optical spectral properties observed at low-z and associated with the first eigenvector is preserved up to z ≈ 2 in a sample of high luminosity quasars. We also describe two major luminosity effects.

  11. Is the Earth's magnetic field heading for a flip? Hints from the past

    Science.gov (United States)

    Laj, C. E.; Kissel, C.

    2017-12-01

    The magnitude of the Earth's dipole magnetic field has decreased significantly over the last centuries at a mean rate of 16 nT/y. This decrease, which correlates with the growth of the South Atlantic Anomaly (SAA) therefore occurs at a rate which is about 10 times larger than expected from a free Ohmic decay process. This situation has led to speculations that an attempt to a reversal or a geomagnetic excursion might be underway. We investigate this hypothesis by examining past geomagnetic instabilities, focussing on the well documented Laschamp and Mono Lake excursions. We have selected high accumulation sedimentary records with very precise age model, leading to unprecedented temporal resolution, and accurate calibration of RPI between 20 and 75 kyr B.P. We also used the 10Be and 36Cl records from the Greenland ice cores. The rate of decay of the field intensity during these two excursions is virtually identical to that observed over the last centuries and much higher than that observed for another period of low intensity (around 65 kyr BP) not associated with a polarity change. Moreover, the global morphology of the Laschamp excursion obtained by Bayesian inversion (Leonhardt et al. (2009) is that reverse magnetic field patches at the core-mantle boundary are formed near the equator and then move poleward, a scenario reminiscent of that described for the present field in the litterature. Therefore, although these results from two excursions do not provide undisputable information on future evolution of the field, they show similarities with several aspects of the present-day geomagnetic field. Assuming that the dynamo processes for an eventual future instability would be similar to those of the past two excursions, we tentatively suggest that, whilst irreversible processes that will drive the geodynamo into a polarity change may have already started, some 1000 years would be needed for the directional changes to start to be significant.

  12. Human airway epithelial cells investigated by atomic force microscopy: A hint to cystic fibrosis epithelial pathology

    International Nuclear Information System (INIS)

    Lasalvia, Maria; Castellani, Stefano; D’Antonio, Palma; Perna, Giuseppe; Carbone, Annalucia; Colia, Anna Laura; Maffione, Angela Bruna; Capozzi, Vito; Conese, Massimo

    2016-01-01

    The pathophysiology of cystic fibrosis (CF) airway disease stems from mutations in the CF Transmembrane Conductance Regulator (CFTR) gene, leading to a chronic respiratory disease. Actin cytoskeleton is disorganized in CF airway epithelial cells, likely contributing to the CF-associated basic defects, i.e. defective chloride secretion and sodium/fluid hypersorption. In this work, we aimed to find whether this alteration could be pointed out by means of Atomic Force Microscopy (AFM) investigation, as roughness and Young's elastic module. Moreover, we also sought to determine whether disorganization of actin cytoskeleton is linked to hypersoption of apical fluid. Not only CFBE41o- (CFBE) cells, immortalized airway epithelial cells homozygous for the F508del CFTR allele, showed a different morphology in comparison with 16HBE14o- (16HBE) epithelial cells, wild-type for CFTR, but also they displayed a lack of stress fibers, suggestive of a disorganized actin cytoskeleton. AFM measurements showed that CFBE cells presented a higher membrane roughness and decreased rigidity as compared with 16HBE cells. CFBE overexpressing wtCFTR became more elongated than the parental CFBE cell line and presented actin stress fibers. CFBE cells absorbed more fluid from the apical compartment. Study of fluid absorption with the F-actin-depolymerizing agent Latrunculin B demonstrated that actin cytoskeletal disorganization increased fluid absorption, an effect observed at higher magnitude in 16HBE than in CFBE cells. For the first time, we demonstrate that actin cytoskeleton disorganization is reflected by AFM parameters in CF airway epithelial cells. Our data also strongly suggest that the lack of stress fibers is involved in at least one of the early step in CF pathophysiology at the levels of the airways, i.e. fluid hypersorption. - Highlights: • CF bronchial epithelial (CFBE) cells show a disorganized actin cytoskeleton. • CFBE cells present high roughness and low rigidity in the plasmamembrane. • CFTR overexpression changes morphology and actin organization. • CFBE cells absorb more apical fluid than wild type bronchial epithelial cells. • Fluid absorption is increased by disorganization of actin cytoskeleton.

  13. Robustness of circadian clocks to daylight fluctuations: hints from the picoeucaryote Ostreococcus tauri.

    Directory of Open Access Journals (Sweden)

    Quentin Thommen

    Full Text Available The development of systemic approaches in biology has put emphasis on identifying genetic modules whose behavior can be modeled accurately so as to gain insight into their structure and function. However, most gene circuits in a cell are under control of external signals and thus, quantitative agreement between experimental data and a mathematical model is difficult. Circadian biology has been one notable exception: quantitative models of the internal clock that orchestrates biological processes over the 24-hour diurnal cycle have been constructed for a few organisms, from cyanobacteria to plants and mammals. In most cases, a complex architecture with interlocked feedback loops has been evidenced. Here we present the first modeling results for the circadian clock of the green unicellular alga Ostreococcus tauri. Two plant-like clock genes have been shown to play a central role in the Ostreococcus clock. We find that their expression time profiles can be accurately reproduced by a minimal model of a two-gene transcriptional feedback loop. Remarkably, best adjustment of data recorded under light/dark alternation is obtained when assuming that the oscillator is not coupled to the diurnal cycle. This suggests that coupling to light is confined to specific time intervals and has no dynamical effect when the oscillator is entrained by the diurnal cycle. This intriguing property may reflect a strategy to minimize the impact of fluctuations in daylight intensity on the core circadian oscillator, a type of perturbation that has been rarely considered when assessing the robustness of circadian clocks.

  14. Avalikustamiskohustuse rikkumine Eesti väärtpaberituruõiguses : tsiviilõiguslikud kaitsevahendid / Meelis Hint

    Index Scriptorium Estoniae

    Hint, Meelis, 1981-

    2003-01-01

    Väärtpaberite avalikustamiskohustusest, tehingu tühistamisest, kahju hüvitamisest, väärtpaberite müügist, kahju hüvitamisest rikkumiste korral ja tehingu tühistamisest väärtpaberite järelturul

  15. Hints on the Lateralization of Dopamine Binding to D-1 Receptors in Rat Striatum

    Czech Academy of Sciences Publication Activity Database

    Franco, R.; Casadó-Anguera, V.; Muňoz, A.; Petrovič, Miloš; Navarro, G.; Moreno, E.; Lanciego, J. L.; Labandeira-García, J. L.; Cortés, A.; Casadó, V.

    2016-01-01

    Roč. 53, č. 8 (2016), s. 5436-5445 ISSN 0893-7648 Institutional support: RVO:67985823 Keywords : lateralization * basal ganglia * G-protein-coupled receptor dimer * dyskinesia * 6-hydroxydopamine Subject RIV: ED - Physiology Impact factor: 6.190, year: 2016

  16. Dark matter searches from the galaxy to the LHC - recent hints and coming progress

    CERN Multimedia

    CERN. Geneva

    2008-01-01

    We discuss the possible galactic positron excess and constraints on interpreting it as dark matter annihilation. We consider wino and higgsino wimps that provide the local relic density and a positron excess (which implies the relic density is non-thermal in origin and important consequences for cosmological history and underlying theories), comment on how to confirm and study these issues at LHC, and on the relation to direct detection experiments.

  17. Mati Hint - sünge keeleteadlane ja pessimistlik ühiskonnategelane / Mari Klein

    Index Scriptorium Estoniae

    Klein, Mari, 1979-

    2007-01-01

    11. septembril peeti Tallinna Ülikoolis seminari, mis oli pühendatud Mati Hindi 70. sünnipäevale. Ettekannetega esinesid ülikoolikaaslased, sõbrad ja kolleegid Rein Veidemann, Haldur Õim, Martin Ehala, Mats Traat, Tapani Lehtinen, Jaan Kaplinski

  18. The new elastic scattering measurements of TOTEM -Are there hints for asymptotics?

    Science.gov (United States)

    Troshin, Sergey M.; Tyurin, Nikolai E.

    2017-03-01

    We point out to another indication of the black-disk limit exceeding in hadron interactions found in the recent impact parameter analysis performed by the TOTEM Collaboration at √{s}=8 TeV and emphasize that this observation might be interpreted as a confirmation of the reflective scattering mode appearance at the LHC energies.

  19. Andro Kööp : "Püüan ruumi tunnet maalida" / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Andro Kööp (sünd. 1967) sellest, kuidas ta sattus sisearhitektuuriga tegelema, oma eelistustest ja harmooniast sisekujunduses, kodu kujundusest jm. A. Kööbist, tema loomingust, omistatud preemiad, valik A. Kööbi kujundatud ühiskondlikke interjööre. Ill.: värv. foto A. Kööbist

  20. Hints on the high-energy seesaw mechanism from the low-energy neutrino spectrum

    International Nuclear Information System (INIS)

    Casas, J.A.; Jimenez-Alburquerque, F.

    2006-12-01

    It is an experimental fact that the mass ratio for the two heavier neutrinos, h=m 3 /m 2 3 /m 2 >> m 3 /m 2 , so m 1 should be extremely tiny. Also, the V R matrix associated to the neutrino Yukawa couplings has a far from random structure, naturally resembling V CKM . In fact we show that identifying V R and V CKM , as well as neutrino and u-quark Yukawa couplings can reproduce h exp in a highly non-trivial way, which is very suggestive. The physical implications of these results are also discussed. (orig.)

  1. Andro Kööp : villa, mis sai ajaloo / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Saaremaal asuva arhitekt Ike Volkovi projekti järgi ehitatud villa sisekujundus. Sisearhitekt Andro Kööp, tema kommentaarid. A. Kööp on kavandanud ka vaibad. Suures osas on villa sisekujunduses kasutatud kataloogimööblit. Ill.: I ja II korruse plaan, 17 värv. vaadet

  2. 3rd Circuit hints it may reconsider McNemar reasoning.

    Science.gov (United States)

    1997-10-17

    The [name removed] v. The Disney Store ruling is under criticism and the 3rd U.S. Circuit Court of Appeals may reconsider its 1996 decision to not allow employees who receive disability benefits to sue under the Americans with Disabilities Act (ADA). A panel of 3rd Circuit judges, working on [name removed] v. American Sterilizer Co., asserts that the [name removed] decision should not be used to assume that an individual's ADA claims are barred because of prior representations of disability. [Name removed] is suing American Sterilizer under the retaliation provisions of the ADA. Other courts are criticizing the [name removed] decision, including the District of Columbia Court in [name removed] v. Washington Metropolitan Area Transit Authority. The [name removed] court assets that a statement made in the context of a disability application does not preclude an ADA claim brought by a worker for illegal discrimination because the ADA and the Social Security Act differ in their statutory intent. AIDS advocates state that the [name removed] decision places a plaintiff in the position of having to choose between asserting a legal right or maintaining an income. Alan Epstein, who represented [name removed], is pleased by the criticism but explains that [name removed], who died this summer, will not be vindicated.

  3. Mari Koger : avatud magamistoaga korter pööningukorrusel / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Korter Nõmmel renoveeritud puumajas (arhitekt Hannes Niineväli). Sisearhitekt Mari Koger, tema kommentaarid. Söögilaua alumiiniumist valatud jalgade autor on Taavi Aunre. Söögilauda valgustab Alberto Meda ja Paolo Rizzatto disainitud lamp Titania. Ill.: plaan, 8 värv. vaadet

  4. The bioethics and law paradox: an argument to maintain separateness with a hint of togetherness.

    Science.gov (United States)

    Werren, Julia

    2007-10-01

    This article analyses how bioethics and law interact and work together. The first half of the article provides definitions of both ethics and bioethics. The article then considers a number of different bioethical standpoints to demonstrate the variance of views in relation to bioethics. In addition, the first half of the article focuses on the different regulatory possibilities in regard to bioethical contexts. This demonstrates that law is of central importance to bioethics. This part also shows that even though law and ethics are often used simultaneously to achieve bioethical goals, law and ethics cannot be used interchangeably. Thus, even though it is somewhat inevitable that law will be used in the pursuit of the goals of bioethics, bioethics and bioethical principle should not be merely a vehicle for law-makers to utilise. The second half of the article focuses on the issues of autonomy and consent to demonstrate how law and ethics have developed in one of the foundation areas of bioethics.

  5. Perceptual strategies of pigeons to detect a rotational centre--a hint for star compass learning?

    Directory of Open Access Journals (Sweden)

    Bianca Alert

    Full Text Available Birds can rely on a variety of cues for orientation during migration and homing. Celestial rotation provides the key information for the development of a functioning star and/or sun compass. This celestial compass seems to be the primary reference for calibrating the other orientation systems including the magnetic compass. Thus, detection of the celestial rotational axis is crucial for bird orientation. Here, we use operant conditioning to demonstrate that homing pigeons can principally learn to detect a rotational centre in a rotating dot pattern and we examine their behavioural response strategies in a series of experiments. Initially, most pigeons applied a strategy based on local stimulus information such as movement characteristics of single dots. One pigeon seemed to immediately ignore eccentric stationary dots. After special training, all pigeons could shift their attention to more global cues, which implies that pigeons can learn the concept of a rotational axis. In our experiments, the ability to precisely locate the rotational centre was strongly dependent on the rotational velocity of the dot pattern and it crashed at velocities that were still much faster than natural celestial rotation. We therefore suggest that the axis of the very slow, natural, celestial rotation could be perceived by birds through the movement itself, but that a time-delayed pattern comparison should also be considered as a very likely alternative strategy.

  6. How Parents Influence School Grades: Hints from a Sample of Adoptive and Biological Families

    Science.gov (United States)

    Johnson, Wendy; McGue, Matt; Iacono, William G.

    2007-01-01

    Using the biological and adoptive families in the Minnesota-based Sibling Interaction and Behavior Study, we investigated the associations among genetic and environmental influences on IQ, parenting, parental expectations for offspring educational attainment, engagement in school, and school grades. All variables showed substantial genetic…

  7. Estimating Dynamical Systems: Derivative Estimation Hints from Sir Ronald A. Fisher

    Science.gov (United States)

    Deboeck, Pascal R.

    2010-01-01

    The fitting of dynamical systems to psychological data offers the promise of addressing new and innovative questions about how people change over time. One method of fitting dynamical systems is to estimate the derivatives of a time series and then examine the relationships between derivatives using a differential equation model. One common…

  8. Using the ERT method in tectonically active areas: hints from Southern Apennine (Italy

    Directory of Open Access Journals (Sweden)

    A. Giocoli

    2008-11-01

    Full Text Available Electrical Resistivity Tomography (ERT method has been used to study two tectonically active areas of southern Apennine (Caggiano Faults and Ufita Basin. The main aim of this job was to study the structural setting of the investigated areas, i.e. the geometry of the basins at depth, the location of active faults at surface, and their geometrical characterization. The comparison between ERT and trench/drilling data allowed us to evaluate the efficacy of the ERT method in studying active faults and the structural setting of seismogenic areas.

    In the Timpa del Vento intermontane basin, high resolution ERT across the Caggiano Fault scarps, with different arrays, electrode spacing (from 1 to 10 m and penetration depth (from about 5 to 40 m was carried out. The obtained resistivity models allowed us to locate the fault planes along the hillslope and to gather information at depth, as later confirmed by paleoseismological trenches excavated across the fault trace.

    In the Ufita River Valley a 3560-m-long ERT was carried out across the basin, joining 11 roll-along multi-channel acquisition system with an electrode spacing of 20 m and reaching an investigation depth of about 170 m. The ERT allowed us to reconstruct the geometry and thickness of the Quaternary deposits filling the Ufita Valley. Our reconstruction of the depositional setting is in agreement with an interpretative geological section based on borehole data.

  9. Flexibility of approach in art practice as research: Hints in Omabe ...

    African Journals Online (AJOL)

    Recently, a number of art institutions (universities) in Europe, America, Asia, and Africa, introduced doctorate programme in studio areas, in which art practice is considered as research. As a new ... installation. The installations elicited public discourse on the tradition and a language of practice stood out from them.

  10. THE PUZZLING EARLY DETECTION OF LOW VELOCITY 56Ni DECAY LINES IN SN 2014J: HINTS OF A COMPACT REMNANT

    International Nuclear Information System (INIS)

    Ouyed, Rachid; Leahy, Denis; Koning, Nico; Staff, Jan

    2015-01-01

    We show that the low-velocity 56 Ni decay lines detected earlier than expected in the type Ia SN 2014J find an explanation in the quark-nova Ia model, which involves the thermonuclear explosion of a tidally disrupted sub-Chandrasekhar white dwarf (WD) in a tight neutron-star-WD binary system. The explosion is triggered by impact from the quark-nova (QN) ejecta on the WD material; the QN is the explosive transition of the neutron star to a quark star (QS) triggered by accretion from a CO torus (the circularized WD material). The presence of a compact remnant (the QS) provides: (1) an additional energy source (spin-down power) which allows us to fit the observed light-curve including the steep early rise; (2) a central gravitational potential which slows down some of the 56 Ni produced to velocities of a few 10 3 km s –1 . In our model, the 56 Ni decay lines become optically visible at ∼20 days from explosion time in agreement with observations. We list predictions that can provide important tests for our model

  11. Gamma-ray and X-ray emission from the Galactic centre: hints on the nuclear star cluster formation history

    Science.gov (United States)

    Arca-Sedda, Manuel; Kocsis, Bence; Brandt, Timothy D.

    2018-06-01

    The Milky Way centre exhibits an intense flux in the gamma and X-ray bands, whose origin is partly ascribed to the possible presence of a large population of millisecond pulsars (MSPs) and cataclysmic variables (CVs), respectively. However, the number of sources required to generate such an excess is much larger than what is expected from in situ star formation and evolution, opening a series of questions about the formation history of the Galactic nucleus. In this paper we make use of direct N-body simulations to investigate whether these sources could have been brought to the Galactic centre by a population of star clusters that underwent orbital decay and formed the Galactic nuclear star cluster (NSC). Our results suggest that the gamma ray emission is compatible with a population of MSPs that were mass segregated in their parent clusters, while the X-ray emission is consistent with a population of CVs born via dynamical interactions in dense star clusters. Combining observations with our modelling, we explore how the observed γ ray flux can be related to different NSC formation scenarios. Finally, we show that the high-energy emission coming from the galactic central regions can be used to detect black holes heavier than 105M⊙ in nearby dwarf galaxies.

  12. Preliminary numerical simulations of the 27 February 2010 Chile tsunami: first results and hints in a tsunami early warning perspective

    Science.gov (United States)

    Tinti, S.; Tonini, R.; Armigliato, A.; Zaniboni, F.; Pagnoni, G.; Gallazzi, Sara; Bressan, Lidia

    2010-05-01

    The tsunamigenic earthquake (M 8.8) that occurred offshore central Chile on 27 February 2010 can be classified as a typical subduction-zone earthquake. The effects of the ensuing tsunami have been devastating along the Chile coasts, and especially between the cities of Valparaiso and Talcahuano, and in the Juan Fernandez islands. The tsunami propagated across the entire Pacific Ocean, hitting with variable intensity almost all the coasts facing the basin. While the far-field propagation was quite well tracked almost in real-time by the warning centres and reasonably well reproduced by the forecast models, the toll of lives and the severity of the damage caused by the tsunami in the near-field occurred with no local alert nor warning and sadly confirms that the protection of the communities placed close to the tsunami sources is still an unresolved problem in the tsunami early warning field. The purpose of this study is two-fold. On one side we perform numerical simulations of the tsunami starting from different earthquake models which we built on the basis of the preliminary seismic parameters (location, magnitude and focal mechanism) made available by the seismological agencies immediately after the event, or retrieved from more detailed and refined studies published online in the following days and weeks. The comparison with the available records of both offshore DART buoys and coastal tide-gauges is used to put some preliminary constraints on the best-fitting fault model. The numerical simulations are performed by means of the finite-difference code UBO-TSUFD, developed and maintained by the Tsunami Research Team of the University of Bologna, Italy, which can solve both the linear and non-linear versions of the shallow-water equations on nested grids. The second purpose of this study is to use the conclusions drawn in the previous part in a tsunami early warning perspective. In the framework of the EU-funded project DEWS (Distant Early Warning System), we will try to give some clues for discussion on the deficiencies of the existing tsunami early warning concepts as regards the warning to the areas which are found close to the tsunami source, and on the strategies that should be followed in the near future in order to make significant progress in the protection and safeguarding of local communities.

  13. 76 FR 37356 - Submission for OMB review; comment request Health Information National Trends Survey 4 (HINTS 4...

    Science.gov (United States)

    2011-06-27

    ...) (OMB 0925-0538, Exp 11/30/2008). Type of Information Collection Request: Reinstatement with Change... understand vital cancer prevention messages. More importantly, this NCI survey will couple knowledge-related... assessment of cancer-related behavior. The Public Health Services Act, Sections 411 (42 U.S.C. 285a) and 412...

  14. When can Empirical Green Functions be computed from Noise Cross-Correlations? Hints from different Geographical and Tectonic environments

    Science.gov (United States)

    Matos, Catarina; Silveira, Graça; Custódio, Susana; Domingues, Ana; Dias, Nuno; Fonseca, João F. B.; Matias, Luís; Krueger, Frank; Carrilho, Fernando

    2014-05-01

    Noise cross-correlations are now widely used to extract Green functions between station pairs. But, do all the cross-correlations routinely computed produce successful Green Functions? What is the relationship between noise recorded in a couple of stations and the cross-correlation between them? During the last decade, we have been involved in the deployment of several temporary dense broadband (BB) networks within the scope of both national projects and international collaborations. From 2000 to 2002, a pool of 8 BB stations continuously operated in the Azores in the scope of the Memorandum of Understanding COSEA (COordinated Seismic Experiment in the Azores). Thanks to the Project WILAS (West Iberia Lithosphere and Astenosphere Structure, PTDC/CTE-GIX/097946/2008) we temporarily increased the number of BB deployed in mainland Portugal to more than 50 (permanent + temporary) during the period 2010 - 2012. In 2011/12 a temporary pool of 12 seismometers continuously recorded BB data in the Madeira archipelago, as part of the DOCTAR (Deep Ocean Test Array Experiment) project. Project CV-PLUME (Investigation on the geometry and deep signature of the Cape Verde mantle plume, PTDC/CTE-GIN/64330/2006) covered the archipelago of Cape Verde, North Atlantic, with 40 temporary BB stations in 2007/08. Project MOZART (Mozambique African Rift Tomography, PTDC/CTE-GIX/103249/2008), covered Mozambique, East Africa, with 30 temporary BB stations in the period 2011 - 2013. These networks, located in very distinct geographical and tectonic environments, offer an interesting opportunity to study seasonal and spatial variations of noise sources and their impact on Empirical Green functions computed from noise cross-correlation. Seismic noise recorded at different seismic stations is evaluated by computation of the probability density functions of power spectral density (PSD) of continuous data. To assess seasonal variations of ambient noise sources in frequency content, time-series of PSD at different frequency bands have been computed. The influence of the spatial and seasonal variation is evaluated by analysis of the one-day length cross-correlations, stacked with a 30-day moving window and with an overlap of 30 days. To inspect the effects of frequency content variations, 30-day cross-correlograms have also been computed at different frequency bands. This work is supported by project QuakeLoc-PT (PTDC/GEO-FIQ/3522/2012) and a contribution to project AQUAREL (PTDC/CTE-GIX/116819/2010).

  15. Simple heuristics in over-the-counter drug choices: a new hint for medical education and practice.

    Science.gov (United States)

    Riva, Silvia; Monti, Marco; Antonietti, Alessandro

    2011-01-01

    Over-the-counter (OTC) drugs are widely available and often purchased by consumers without advice from a health care provider. Many people rely on self-management of medications to treat common medical conditions. Although OTC medications are regulated by the National and the International Health and Drug Administration, many people are unaware of proper dosing, side effects, adverse drug reactions, and possible medication interactions. This study examined how subjects make their decisions to select an OTC drug, evaluating the role of cognitive heuristics which are simple and adaptive rules that help the decision-making process of people in everyday contexts. By analyzing 70 subjects' information-search and decision-making behavior when selecting OTC drugs, we examined the heuristics they applied in order to assess whether simple decision-making processes were also accurate and relevant. Subjects were tested with a sequence of two experimental tests based on a computerized Java system devised to analyze participants' choices in a virtual environment. We found that subjects' information-search behavior reflected the use of fast and frugal heuristics. In addition, although the heuristics which correctly predicted subjects' decisions implied significantly fewer cues on average than the subjects did in the information-search task, they were accurate in describing order of information search. A simple combination of a fast and frugal tree and a tallying rule predicted more than 78% of subjects' decisions. The current emphasis in health care is to shift some responsibility onto the consumer through expansion of self medication. To know which cognitive mechanisms are behind the choice of OTC drugs is becoming a relevant purpose of current medical education. These findings have implications both for the validity of simple heuristics describing information searches in the field of OTC drug choices and for current medical education, which has to prepare competent health specialists to orientate and support the choices of their patients.

  16. Simple heuristics in over-the-counter drug choices: a new hint for medical education and practice

    Science.gov (United States)

    Riva, Silvia; Monti, Marco; Antonietti, Alessandro

    2011-01-01

    Introduction Over-the-counter (OTC) drugs are widely available and often purchased by consumers without advice from a health care provider. Many people rely on self-management of medications to treat common medical conditions. Although OTC medications are regulated by the National and the International Health and Drug Administration, many people are unaware of proper dosing, side effects, adverse drug reactions, and possible medication interactions. Purpose This study examined how subjects make their decisions to select an OTC drug, evaluating the role of cognitive heuristics which are simple and adaptive rules that help the decision-making process of people in everyday contexts. Subjects and methods By analyzing 70 subjects’ information-search and decision-making behavior when selecting OTC drugs, we examined the heuristics they applied in order to assess whether simple decision-making processes were also accurate and relevant. Subjects were tested with a sequence of two experimental tests based on a computerized Java system devised to analyze participants’ choices in a virtual environment. Results We found that subjects’ information-search behavior reflected the use of fast and frugal heuristics. In addition, although the heuristics which correctly predicted subjects’ decisions implied significantly fewer cues on average than the subjects did in the information-search task, they were accurate in describing order of information search. A simple combination of a fast and frugal tree and a tallying rule predicted more than 78% of subjects’ decisions. Conclusion The current emphasis in health care is to shift some responsibility onto the consumer through expansion of self medication. To know which cognitive mechanisms are behind the choice of OTC drugs is becoming a relevant purpose of current medical education. These findings have implications both for the validity of simple heuristics describing information searches in the field of OTC drug choices and for current medical education, which has to prepare competent health specialists to orientate and support the choices of their patients. PMID:23745077

  17. The Orientalisation of North Africa: New hints from the study of autosomal STRs in an Arab population.

    Science.gov (United States)

    Elkamel, Sarra; Cherni, Lotfi; Alvarez, Luis; Marques, Sofia L; Prata, Maria J; Boussetta, Sami; Benammar-Elgaaied, Amel; Khodjet-El-Khil, Houssein

    2017-03-01

    Recent genomic analyses suggest that the current North African gene pool was mainly influenced by population flow coming from the East that altered the genetic structure of autochthonous Berber populations. Such genetic flow has not been extensively addressed yet using North African populations of Middle-eastern origin as reference. To discern the Middle-eastern component in the genetic background of Tunisian Arabs and evaluate the extent of gene flow from the Middle East into North African autochthonous Berber populations. This study has examined 113 Tunisians of well-known Arabian origin from Kairouan region, using 15 autosomal Short Tandem Repeats (STRs) loci. No deviations from Hardy-Weinberg equilibrium were observed and all loci presented high levels of heterozygosity. Principal coordinate and STRUCTURE analyses were consistent in clustering together North African and Middle Eastern populations, likely reflecting the recent gene flow from the East dating back to the Arab conquest period. This demographic migration and the Arabisation process that submerged the original Berber language and customs seems to have be accompanied by substantial gene flow and genetic admixture. This study represents an additional step to obtain a comprehensive understanding of the complex demographic history of North African populations.

  18. Extremely low genetic diversity across mangrove taxa reflects past sea level changes and hints at poor future responses.

    Science.gov (United States)

    Guo, Zixiao; Li, Xinnian; He, Ziwen; Yang, Yuchen; Wang, Wenqing; Zhong, Cairong; Greenberg, Anthony J; Wu, Chung-I; Duke, Norman C; Shi, Suhua

    2018-04-01

    The projected increases in sea levels are expected to affect coastal ecosystems. Tropical communities, anchored by mangrove trees and having experienced frequent past sea level changes, appear to be vibrant at present. However, any optimism about the resilience of these ecosystems is premature because the impact of past climate events may not be reflected in the current abundance. To assess the impact of historical sea level changes, we conducted an extensive genetic diversity survey on the Indo-Malayan coast, a hotspot with a large global mangrove distribution. A survey of 26 populations in six species reveals extremely low genome-wide nucleotide diversity and hence very small effective population sizes (N e ) in all populations. Whole-genome sequencing of three mangrove species further shows the decline in N e to be strongly associated with the speed of past changes in sea level. We also used a recent series of flooding events in Yalong Bay, southern China, to test the robustness of mangroves to sea level changes in relation to their genetic diversity. The events resulted in the death of half of the mangrove trees in this area. Significantly, less genetically diverse mangrove species suffered much greater destruction. The dieback was accompanied by a drastic reduction in local invertebrate biodiversity. We thus predict that tropical coastal communities will be seriously endangered as the global sea level rises. Well-planned coastal development near mangrove forests will be essential to avert this crisis. © 2017 John Wiley & Sons Ltd.

  19. Paralog-divergent Features May Help Reduce Off-target Effects of Drugs: Hints from Glucagon Subfamily Analysis

    Directory of Open Access Journals (Sweden)

    Zhining Sa

    2017-08-01

    Full Text Available Side effects from targeted drugs remain a serious concern. One reason is the nonselective binding of a drug to unintended proteins such as its paralogs, which are highly homologous in sequences and have similar structures and drug-binding pockets. To identify targetable differences between paralogs, we analyzed two types (type-I and type-II of functional divergence between two paralogs in the known target protein receptor family G-protein coupled receptors (GPCRs at the amino acid level. Paralogous protein receptors in glucagon-like subfamily, glucagon receptor (GCGR and glucagon-like peptide-1 receptor (GLP-1R, exhibit divergence in ligands and are clinically validated drug targets for type 2 diabetes. Our data showed that type-II amino acids were significantly enriched in the binding sites of antagonist MK-0893 to GCGR, which had a radical shift in physicochemical properties between GCGR and GLP-1R. We also examined the role of type-I amino acids between GCGR and GLP-1R. The divergent features between GCGR and GLP-1R paralogs may be helpful in their discrimination, thus enabling the identification of binding sites to reduce undesirable side effects and increase the target specificity of drugs.

  20. PROFIBUS-DP. Fundamentals and hints for users; PROFIBUS-DP. Grundlagen, Tips und Tricks fuer Anwender

    Energy Technology Data Exchange (ETDEWEB)

    Popp, M.

    1998-04-01

    PROFIBUS-DP is one of the most common field buses for industrial communication. The author provides competent help in using this technology. He describes 32 of the most common errors found in certification tests and shows how they can be remedies. Fundamentals and enhancements of PROFIBUS-DP are presented. PROFIBUS-DP telegrams for data interpretation are discussed at length, as are extensive GSD files. Particular emphasis is given to the projecting and commissioning of a system and practical guides for installation. (orig.) [Deutsch] PROFIBUS-DP gehoert zu den am haeufigsten eingesetzten Feldbussen fuer die industrielle Kommunikation. Der Autor bietet in diesem umfassenden Werk kompetente Unterstuetzung bei der Anwendung dieser Feldbustechnik. Es werden 32 der haeufigsten Fehler, die bei Zertifizierungstests festgestellt wurden, beschrieben und Wege zu ihrer Behebung dargestellt. Die Grundlagen von PROFIBUS-DP werden erlaeutert und die PROFIBUS-Erweiterungen vorgestellt. PROFIBUS-DP-Telegramme zur Interpretation des Datenverkehrs werden genauso detailliert erklaert wie eine umfangreiche GSD-Datei. Ein besonderer Schwerpunkt ist die Projektierung und Inbetriebnahme einer Anlage und den praxisgerechten Aufbaurichtlinien gewidmet. (orig./GL)

  1. Arukaotus haridus- ja teadussüsteemis : praegu toimuv tundub mõnes valdkonnas absurditeatrina / Mati Hint

    Index Scriptorium Estoniae

    Hint, Mati

    2004-01-01

    Autor avaldab pahameelt Eesti haridus- ja teadussüsteemis toimuva üle, hindamissüsteemi muutmise ning ülikoolides õpetatavate erialade õppekavade ja õppe- ja teadusliku töö taseme rahvusvahelise hindamise kriteeriumide kohta

  2. Factors Influencing Communication with Doctors via the Internet: A Cross-Sectional Analysis of 2014 HINTS Survey.

    Science.gov (United States)

    Jiang, Shaohai; Street, Richard L

    2017-02-01

    Based on Street's (2003) ecological framework of communication in medical encounters, this study examined personal, interpersonal, and media factors that could influence patients' use of the Internet to communicate with doctors. Results from data analysis of responses from the 2014 Health Information National Trends Survey showed that patient activation and ease of Internet access were two positive predictors of online doctor-patient communication. In addition, patients' trust in doctors positively moderated the relationships between patient activation and online doctor-patient communication, and between perceived health status and online doctor-patient communication. Finally, the quality of patients' past experiences communicating with doctors had a positive moderation effect on the association between health information seeking behavior and online doctor-patient communication. Implications and limitations are discussed.

  3. Chlorophyll-a Estimation Around the Antarctica Peninsula Using Satellite Algorithms: Hints from Field Water Leaving Reflectance

    Directory of Open Access Journals (Sweden)

    Chen Zeng

    2016-12-01

    Full Text Available Ocean color remote sensing significantly contributes to our understanding of phytoplankton distribution and abundance and primary productivity in the Southern Ocean (SO. However, the current SO in situ optical database is still insufficient and unevenly distributed. This limits the ability to produce robust and accurate measurements of satellite-based chlorophyll. Based on data collected on cruises around the Antarctica Peninsula (AP on January 2014 and 2016, this research intends to enhance our knowledge of SO water and atmospheric optical characteristics and address satellite algorithm deficiency of ocean color products. We collected high resolution in situ water leaving reflectance (±1 nm band resolution, simultaneous in situ chlorophyll-a concentrations and satellite (MODIS and VIIRS water leaving reflectance. Field samples show that clouds have a great impact on the visible green bands and are difficult to detect because NASA protocols apply the NIR band as a cloud contamination threshold. When compared to global case I water, water around the AP has lower water leaving reflectance and a narrower blue-green band ratio, which explains chlorophyll-a underestimation in high chlorophyll-a regions and overestimation in low chlorophyll-a regions. VIIRS shows higher spatial coverage and detection accuracy than MODIS. After coefficient improvement, VIIRS is able to predict chlorophyll a with 53% accuracy.

  4. Physical activity in young adults: a signal detection analysis of Health Information National Trends Survey (HINTS) 2007 data.

    Science.gov (United States)

    Valle, Carmina G; Tate, Deborah F; Mayer, Deborah K; Allicock, Marlyn; Cai, Jianwen; Campbell, Marci K

    2015-01-01

    Many young adults are insufficiently active to achieve the health benefits of regular physical activity. Using signal detection analysis of data from the 2007 Health Information National Trends Survey, the authors examined distinct subgroups of 18-39 year-old adults who vary in their likelihood of not meeting physical activity recommendations. We randomly split the sample and conducted signal detection analysis on the exploratory half to identify subgroups and interactions among sociodemographic and health communication variables that predicted engaging in less than 150 minutes per week of moderate-intensity physical activity (low physical activity). We compared rates of low physical activity among subgroups with similarly defined subgroups in the validation sample. Overall, 62% of participants did not meet physical activity recommendations. Among 8 subgroups identified, low physical activity rates ranged from 31% to 90%. Predictors of low physical activity were general health, body mass index (BMI), perceived cancer risk, health-related Internet use, and trust in information sources. The least active subgroup (90% low physical activity) included young adults in poor to good health with a BMI of 30.8 or more (obese). The most active subgroup (31% low physical activity) comprised those in very good to excellent health, who used a website to help with diet, weight, or physical activity, and had little to no trust in health information on television. Findings suggest potential intervention communication channels and can inform targeted physical activity interventions for young adults.

  5. Chlorophyll-a Estimation Around the Antarctica Peninsula Using Satellite Algorithms: Hints from Field Water Leaving Reflectance.

    Science.gov (United States)

    Zeng, Chen; Xu, Huiping; Fischer, Andrew M

    2016-12-07

    Ocean color remote sensing significantly contributes to our understanding of phytoplankton distribution and abundance and primary productivity in the Southern Ocean (SO). However, the current SO in situ optical database is still insufficient and unevenly distributed. This limits the ability to produce robust and accurate measurements of satellite-based chlorophyll. Based on data collected on cruises around the Antarctica Peninsula (AP) on January 2014 and 2016, this research intends to enhance our knowledge of SO water and atmospheric optical characteristics and address satellite algorithm deficiency of ocean color products. We collected high resolution in situ water leaving reflectance (±1 nm band resolution), simultaneous in situ chlorophyll-a concentrations and satellite (MODIS and VIIRS) water leaving reflectance. Field samples show that clouds have a great impact on the visible green bands and are difficult to detect because NASA protocols apply the NIR band as a cloud contamination threshold. When compared to global case I water, water around the AP has lower water leaving reflectance and a narrower blue-green band ratio, which explains chlorophyll-a underestimation in high chlorophyll-a regions and overestimation in low chlorophyll-a regions. VIIRS shows higher spatial coverage and detection accuracy than MODIS. After coefficient improvement, VIIRS is able to predict chlorophyll a with 53% accuracy.

  6. Synchrotron FT-IR analyses of microstructured biomineral domains: Hints to the biomineralization processes in freshwater cultured pearls.

    Science.gov (United States)

    Soldati, A. L.; Vicente-Vilas, V.; Gasharova, B.; Jacob, D. E.

    2009-04-01

    Recent investigations in freshwater cultured pearls (bio-carbonate) by micro-Raman spectroscopy (Wehrmeister et al., 2008; Soldati et al., 2008), Scanning Electron Microscopy (SEM) and Transmission Electron Microscopy (TEM) imaging (Jacob et al., 2008) show that the pearl biomineralisation starts with a self assembling process in which an existing gel matrix of amorphous calcium carbonate (ACC) and organic substances reorganizes and conglomerates in small domains; these conglomerates then form prisms and mature nacreous tablets of aragonite or vaterite. Raman spectroscopy shows that the calcium carbonate polymorphs have decreasing luminescence in the order ACC>Vaterite>Aragonite, coinciding with decreasing quantities of S and P (related to the organic matrix) measured by Laser Ablation Inductively Coupled Plasma Mass Spectroscopy (LA-ICP-MS) and Electron Probe Micro Analyzer (EPMA). Although little is known about the process of transformation of the ACC gel into vaterite and aragonite, it is speculated that this probably involves dehydration and change of the accompanying organic matrix. This is also supported by our laboratory FT-IR analysis. However, due to the small size of the areas of ACC (about 10 ?m) and the biogenic crystals an in-situ high spatially resolved IR-method is needed to record how the water content and organic matrix change in the biomineralisation sequence, to understand which processes take place in the self-organization. The beamline IR-1 at the ANKA synchrotron source (Karlsruhe, Germany) was used for this experiment. Freshwater cultured pearls from China cultured in Hyriopsis cumingii mussels by tissue nucleation methods (so-called beadless pearls) as well as by bead implantation methods (aragonite nucleus) were studied. The pearls were cut in half with a diamond-plated saw and polished with diamond paste on a copper plate. Micro-Raman spectroscopy maps (Department of Geosciences, at the Johannes Gutenberg-University, Mainz) were generated to identify and pre-select those pearls containing ACC. Infrared absorption spectra were measured using a Ge ATR objective on 100-200 ?m thin sections and polished pearl sections. Attenuated total reflectance spectroscopy gives the opportunity to measure the infrared absorption in a reflectance mode directly without necessity to apply Kramers-Kronig transformation. The spectral range available is 650-5000 cm-1when using a Ge ATR crystal with the MCT detector at the ANKA-IR microscope and allowed the detection of the ?4 in-plane bending band (around 750 cm-1 in vaterite and 710 cm-1 in aragonite), the ?1 symmetric stretching bands (1070-7085 cm-1 for vaterite4 and 1082-1084 cm-1 in aragonite5), the ?2 out-of-plane bending vibration of the CO3 groups (855 cm-1 for vaterite and 857-877 cm-1 in aragonite) and the ?3 asymmetric stretching (1420-1490 cm-1 in vaterite and 1480 cm-1 in aragonite) respectively (Sato and Masuda, 1969; Yamoto et al., 1974).Water was detected by the presence of the O-H stretching at around 3500 cm-1. Proteins and sugars included in the biogenic carbonates were recognized through the N-H and C-H bands, for example 1717-1575 cm-1 for aspartic acid, 1712-1558 cm-1 for glutamic acid, 1500 to 2000 cm-1 amide I and II (Dauphin et al., 2006). References WEHRMEISTER U., JACOB D.E., SOLDATI A.L., HÄGER T. & HOFMEISTER W. 2007. Vaterite in freshwater cultured pearls from China and Japan. The Journal of Gemmology; 31: 269-276. SOLDATI A.L., JACOB D.E., WEHRMEISTER U.& HOFMEISTER W. 2008. Structural characterization and chemical composition of aragonite and vaterite in freshwater cultured pearls. Mineralogical Magazine 72: 577-590. JACOB, D.E., SOLDATI, A.L., WIRTH, R., HUTH, J., WEHRMEISTER, U. & HOFMEISTER, W. 2008. Nanostructure, composition and mechanisms of bivalve shell growth. Geochimica et Coscmochimica Acta 72: 5401-5415. SATO M. & MATSUDA S. 1969. Structure of vaterite and infrared spectra. Z. Kistalography 129: 405-410. YAMAMOTO A, SHIRO Y & MURATA H. 1974 Optically-active vibrations and elastic constants of calcite and aragonite. Bulletin Chemical Society Japan, 47:265-273. DAUPHIN Y. 2006. Structure and composition of steptal nacreous layer of Nautilus macromphalus L. (Mollusca, Cephalopoda). Zoology 109: 95-95.

  7. Riia Oja : maja läbi kolme korruse ja kahe tänava / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Tallinnas Uuel tänaval asuva eramu sisekujundus. Hoone on ehitatud 19. sajandi lõpul Pikal tänaval asuva elamu pesuköögiks. Sisearhitekt Riia Oja, kes projekteeris ka köögimööbli. vitraažid tegi Kaie Pärn. Renoveerimistöid teostas Hard Restauraator. Riia Oja ja omaniku kommentaarid. Ill.: korruste plaanid, 7 värv. vaadet

  8. The Effect of Hints and Model Answers in a Student-Controlled Problem-Solving Program for Secondary Physics Education

    NARCIS (Netherlands)

    Pol, Henk J.; Harskamp, Egbert G.; Suhre, Cor J. M.; Goedhart, Martin J.

    Many students experience difficulties in solving applied physics problems. Most programs that want students to improve problem-solving skills are concerned with the development of content knowledge. Physhint is an example of a student-controlled computer program that supports students in developing

  9. Nonenzymatic Oligomerization of 3 ',5 '-Cyclic CMP Induced by Proton and UV Irradiation Hints at a Nonfastidious Origin of RNA

    Czech Academy of Sciences Publication Activity Database

    Costanzo, G.; Giorgi, A.; Scipioni, A.; Timperio, A.M.; Mancone, C.; Tripodis, N.; Kapralov, M.; Krasavin, E.; Kruse, Holger; Šponer, Jiří; Šponer, Judit E.; Ranc, V.; Otyepka, M.; Pino, S.; Di Mauro, E.

    2017-01-01

    Roč. 18, č. 15 (2017), s. 1535-1543 ISSN 1439-4227 R&D Projects: GA ČR GA17-05076S Institutional support: RVO:68081707 Keywords : template-directed synthesis * prebiotic chemistry * montmorillonite catalysis Subject RIV: CE - Biochemistry OBOR OECD: Biochemistry and molecular biology Impact factor: 2.847, year: 2016

  10. Breast cancer arising within fibroadenoma: collective analysis of case reports in the literature and hints on treatment policy.

    Science.gov (United States)

    Wu, Yu-Ting; Chen, Shou-Tung; Chen, Chih-Jung; Kuo, Yao-Lung; Tseng, Ling-Ming; Chen, Dar-Ren; Kuo, Shou-Jen; Lai, Hung-Wen

    2014-11-10

    Breast cancer arising within a fibroadenoma (BcaFad) is rare; the rate varies from 0.002% to 0.125% in fibroadenoma specimens. Owing to its rarity, the clinicopathologic feature and treatment principle of BcaFad is still not clear. Therefore, the aim of this study was to perform a collective analysis of case reports in the literature to identify the characteristics and optimal treatment for BcaFad. We analyzed an aggregated sample of 30 patients with BcaFad from case reports in the literature (n=24 cases) and our present study (n=6 cases). We collected and analyzed the clinicopathologic features and prognoses of patients with BcaFad, as well as treatments they received. The patients' mean age at diagnosis was 46.9 years. Twenty BcaFad patients (66.7%) received breast-conserving surgery (BCS), and nine other patients (30.0%) were treated with mastectomy. The rate of lymph node metastasis in BcaFad patients was 23.8%. The breakdown of the histological types of BcaFad was invasive ductal carcinoma (53.3%), followed by ductal carcinoma in situ (23.3%), lobular carcinoma in situ (16.7%) and invasive lobular carcinoma (13.3%). More than half of patients with positive hormone receptor status received hormone therapy. Most BcaFad patients with lymph node metastases received chemotherapy, and 20.0% of BcaFad patients treated with BCS received further radiotherapy. Only one patient had recurrence after surgery, and another had lung metastasis when diagnosed with BcaFad. Most BcaFad patients could be managed by BCS. Adjuvant radiotherapy could be performed, but was not mandatory. Chemotherapy should be considered as a treatment option in the presence of lymph node metastasis.

  11. Regional climate pattern during two millennia estimated from annual tree rings of Yaku cedar trees: a hint for solar variability?

    Science.gov (United States)

    Muraki, Yasushi; Mitsutani, Takumi; Shibata, Shoichi; Kuramata, Syuichi; Masuda, Kimiaki; Nagaya, Kentaro

    2015-02-01

    We analyzed trees that have survived on Yaku island (Yakushima) for 2,000 years. Quite surprisingly, the Fourier and wavelet analyses of the annual growth rate identified 2 cycles of periodicities of 11 and (24 ± 4) years during the Oort, Wolf, Spörer, Maunder, and Dalton minima. The 11-year periodicity originated from solar activity, while the (24 ± 4)-year periodicity may be related to the Pacific Decadal Oscillation (PDO). In particular, we have discovered an 11-year periodicity in the meteorological daylight-hour data from Yakushima in the month of June during 1938 to 2013 and a 24-year periodicity in July. The growth rate of the tree rings may be affected by the variation of the daylight hour.

  12. Galaxy formation in the reionization epoch as hinted by Wide Field Camera 3 observations of the Hubble Ultra Deep Field

    International Nuclear Information System (INIS)

    Yan Haojing; Windhorst, Rogier A.; Cohen, Seth H.; Hathi, Nimish P.; Ryan, Russell E.; O'Connell, Robert W.; McCarthy, Patrick J.

    2010-01-01

    We present a large sample of candidate galaxies at z ∼ 7-10, selected in the Hubble Ultra Deep Field using the new observations of the Wide Field Camera 3 that was recently installed on the Hubble Space Telescope. Our sample is composed of 20 z 850 -dropouts (four new discoveries), 15 Y 105 -dropouts (nine new discoveries) and 20 J 125 -dropouts (all new discoveries). The surface densities of the z 850 -dropouts are close to what was predicted by earlier studies, however, those of the Y 105 - and J 125 -dropouts are quite unexpected. While no Y 105 - or J 125 -dropouts have been found at AB ≤ 28.0 mag, their surface densities seem to increase sharply at fainter levels. While some of these candidates seem to be close to foreground galaxies and thus could possibly be gravitationally lensed, the overall surface densities after excluding such cases are still much higher than what would be expected if the luminosity function does not evolve from z ∼ 7 to 10. Motivated by such steep increases, we tentatively propose a set of Schechter function parameters to describe the luminosity functions at z ∼ 8 and 10. As compared to their counterpart at z ∼ 7, here L * decreases by a factor of ∼ 6.5 and φ * increases by a factor of 17-90. Although such parameters are not yet demanded by the existing observations, they are allowed and seem to agree with the data better than other alternatives. If these luminosity functions are still valid beyond our current detection limit, this would imply a sudden emergence of a large number of low-luminosity galaxies when looking back in time to z ∼ 10, which, while seemingly exotic, would naturally fit in the picture of the cosmic hydrogen reionization. These early galaxies could easily account for the ionizing photon budget required by the reionization, and they would imply that the global star formation rate density might start from a very high value at z ∼ 10, rapidly reach the minimum at z ∼ 7, and start to rise again towards z ∼ 6. In this scenario, the majority of the stellar mass that the universe assembled through the reionization epoch seems still undetected by current observations at z ∼ 6. (research papers)

  13. Media exposure and tobacco product addiction beliefs: Findings from the 2015 Health Information National Trends Survey (HINTS-FDA 2015).

    Science.gov (United States)

    Donaldson, Elisabeth A; Hoffman, Allison C; Zandberg, Izabella; Blake, Kelly D

    2017-09-01

    Addiction beliefs about tobacco use are associated with intentions to use and use of tobacco products. Exposure to information about tobacco products in media sources may affect addiction beliefs. To examine the relationship between media exposure and tobacco product addiction beliefs. A nationally representative sample of US adults (n=3738) from the 2015 National Cancer Institute's Health Information National Trends Survey was used to examine addiction beliefs about cigarettes, cigars, smokeless tobacco, electronic cigarettes, hookah/waterpipe tobacco, and roll-your-own cigarettes. We used logistic regression to examine the relationship between media exposure and addiction beliefs. We defined media exposure by hours exposed, as well as exposure to tobacco use health effects information through media sources including social media. We categorized media sources by whether respondents actively or passively engaged with the source. A majority (60.6% to 87.3%) of respondents believed that cigarettes, cigars, roll-your-own cigarettes and smokeless tobacco are addictive. Less than half of respondents believed that electronic cigarettes or hookah/waterpipes are addictive (45.2% and 49.8%, respectively). Respondents exposed to messages about tobacco use health effects on active media channels (e.g., social media) had greater odds of believing that smokeless tobacco (adjusted odds ratio [AOR]=1.48), hookah/waterpipe (AOR=1.69), and roll-your-own cigarettes (AOR=1.61) are addictive. Respondents exposed to tobacco use health effects messages on passive media channels (e.g., television), had greater odds of believing that cigarettes (AOR=2.76) and electronic cigarettes (AOR=2.12) are addictive. US adult exposure to information about the health effects of tobacco use was associated with addiction beliefs about tobacco products. Published by Elsevier Ltd.

  14. The Emilia 2012 seismic sequence: hints on incipient basement-involved deformation in the foreland of the Northern Apennines (Italy)

    Science.gov (United States)

    Argnani, Andrea; Carannante, Simona; Massa, Marco; D'Alema, Ezio; Lovati, Sara

    2015-04-01

    The deformation front of the Northern Apennines is buried under the sediments of the Po Plain and was formed mainly during the Pliocene. The remarkably arcuate shape of the thrust front contrasts with the linear northwestern trend of the pede-Apennines, where recent deformation is documented by both geological and geodetic evidence. This study presents new geological and seismological data that are used to assess the structural style of the Ferrara Arc, a sector of the Northern Apennine front that was hit by two strong earthquakes on May 20 (MW 6.1) and May 29 (MW 6.0), 2012. The proposed interpretation is based on a dense grid of commercial seismic profiles and exploration wells, and high-quality relocation of ~5,300 earthquakes (the Emilia sequence). The seismicity was used to calibrate new one-dimensional and three-dimensional local Vp and Vs velocity models for the area. On the basis of these new models, the initial sparse hypocenters were then relocated in absolute mode and adjusted using the double-difference relative location algorithm. Seismicity distribution is elongated in the W-NW to E-SE directions, reaching a depth of 10-12 km. The aftershocks of the May 20 mainshock appear to be distributed on a rupture surface that dips ~45° SSW, and the surface projection indicates an area ~10 km wide and 23 km long. The aftershocks of the May 29 second mainshock followed a steep rupture surface that is well constrained within the investigated volume, whereby the surface projection of the blind source indicates an area ~6 km wide and 33 km long. The analysed multichannel seismic profiles highlight the presence of relevant lateral variations in the structural style of the Ferrara folds that developed during the Pliocene and Pleistocene, and also show the occurrence of a Mesozoic extensional fault system in the Ferrara arc, which in places has been seismically reactivated. These geological and seismological observations suggest that the 2012 Emilia earthquakes were related to ruptures along blind fault surfaces that are not part of the Pliocene-Pleistocene structural system, but are instead related to a deeper system that is itself closely related to re-activation of a Mesozoic extensional fault system. The implication is that the Emilia 2012 seismic sequence was related to activation of a new deformation system that has developed since the late Pleistocene and that affects the deeper structural levels within the Adriatic crust. This interpretation has major relevance for the seismotectonic characterization of the Po Plain, because the location and extent of the Ferrara folds, that were formed during the Pliocene-Pleistocene, cannot simply be used to estimate the seismogenic potential of the Ferrara Arc region.

  15. Hint of Universal Law for the Financial Gains of Competitive Sport Teams. The case of Tour de France cycle race.

    Science.gov (United States)

    Ausloos, Marcel

    2017-12-01

    This short note is intended as a "Letter to the Editor" Perspective in order that it serves as a contribution, in view of reaching the physics community caring about rare events and scaling laws and unexpected findings, on a domain of wide interest: sport and money. It is apparent from the data reported and discussed below that the scarcity of such data does not allow to recommend a complex elaboration of an agent based model, - at this time. In some sense, this also means that much data on sport activities is not necessarily given in terms of physics prone materials, but it could be, and would then attract much attention. Nevertheless the findings tie the data to well known scaling laws and physics processes. It is found that a simple scaling law describes the gains of teams in recent bicycle races, like the Tour de France. An analogous case, ranking teams in Formula 1 races, is shown in an Appendix

  16. Stress in School. Some Empirical Hints on the Circadian Cortisol Rhythm of Children in Outdoor and Indoor Classes.

    Science.gov (United States)

    Dettweiler, Ulrich; Becker, Christoph; Auestad, Bjørn H; Simon, Perikles; Kirsch, Peter

    2017-04-30

    This prospective longitudinal survey compared the stress levels of students taught using an outdoor curriculum in a forest, with children in a normal school setting. We were especially interested in the effect outdoor teaching might have on the children's normal diurnal cortisol rhythm. 48 children (mean age = 11.23; standard deviation (SD) = 0.46) were enrolled, with 37 in the intervention group (IG), and 11 in the control group (CG). The intervention consisted of one full school day per week in the forest over the school year. Stress levels were measured in cortisol with three samples of saliva per day. Furthermore, the data allowed for statistical control of physical activity (PA) values. For data analysis, we used a linear mixed-effects model (LMM) with random intercept and general correlation matrix for the within-unit residuals. The LMM yields that IG have expected greater decline of cortisol compared to CG; rate 0.069 µg/L vs. 0.0102 µg/L (log-units/2 h), p = 0.009. PA does not show a statistically significant interaction with cortisol ( p = 0.857), despite being higher in the intervention group ( p child's diurnal rhythm, with a significant decline of cortisol from morning to noon. This effect is constant over the school year. The CG does not show this decline during either measurement day. Further research is needed to fully explain this interesting phenomenon.

  17. Implications of social media use on health information technology engagement: Data from HINTS 4 cycle 3.

    Science.gov (United States)

    Jackson, Devlon N; Chou, Wen-Ying Sylvia; Coa, Kisha I; Oh, April; Hesse, Bradford

    2016-12-01

    Little is known about the association between Internet/social media use and health information technology (HIT) engagement. This study examines patterns of social media use and HIT engagement in the U.S.A. using data from the 2013 Health Information National Trends Survey (N = 3,164). Specifically, predictors of two HIT activities (i.e., communicating with a healthcare provider using the Internet or email and tracking personal health information electronically) are examined. Persons who were females, higher education, non-Hispanic others, having a regular healthcare provider, and ages 35-44 were more likely to participate in HIT activities. After controlling for sociodemographics and health correlates, social media use was significantly associated with HIT engagement. To our knowledge, this is one of the first studies to systematically examine the use and relationships across multiple types of health-related online media.

  18. Akhet Khufu: archaeo-astronomical hints at a common project of the two main pyramids of Giza, Egypt

    OpenAIRE

    Magli, Giulio

    2007-01-01

    The architectural complexes composed by the two main pyramids of Giza together with their temples are investigated from an inter-disciplinary point of view, taking into account their astronomical alignments as well as their relationships with the visible landscape. Combining already known facts together with new clues, the work strongly supports the idea that the two complexes were conceived as parts of a common project.

  19. Effects of layered crust on the coseismic slip inversion and related CFF variations: Hints from the 2012 Emilia Romagna earthquake

    Science.gov (United States)

    Nespoli, Massimo; Belardinelli, Maria E.; Anderlini, Letizia; Bonafede, Maurizio; Pezzo, Giuseppe; Todesco, Micol; Rinaldi, Antonio P.

    2017-12-01

    The 2012 Emilia Romagna (Italy) seismic sequence has been extensively studied given the occurrence of two mainshocks, both temporally and spatially close to each other. The recent literature accounts for several fault models, obtained with different inversion methods and different datasets. Several authors investigated the possibility that the second event was triggered by the first mainshock with elusive results. In this work, we consider all the available InSAR and GPS datasets and two planar fault geometries, which are based on both seismological and geological constraints. We account for a layered, elastic half-space hosting the dislocation and compare the slip distribution resulting from the inversion and the related changes in Coulomb Failure Function (CFF) obtained with both a homogeneous and layered half-space. Finally, we focus on the interaction between the two main events, discriminating the contributions of coseismic and early postseismic slip of the mainshock on the generation of the second event and discuss the spatio-temporal distribution of the seismic sequence. When accounting for both InSAR and GPS geodetic data we are able to reproduce a detailed coseismic slip distribution for the two mainshocks that is in accordance with the overall aftershock seismicity distribution. Furthermore, we see that an elastic medium with depth dependent rigidity better accounts for the lack of the shallow seismicity, amplifying, with respect to the homogeneous case, the mechanical interaction of the two mainshocks.

  20. Some correlations between eight types of malignant neoplasms: A hint from cancer dynamics of 31 European countries in 20 years

    Directory of Open Access Journals (Sweden)

    WenJun Zhang

    2017-09-01

    Full Text Available In present study, the data of standardised death rates of malignant neoplasms per 100000 inhabitants in 31 European countries during 1994-2013 were used to analyze linear correlations between eight types of cancers in terms of induced death rates. The results showed that most pairs of cancers closely correlate to each other. The malignant neoplasm of cervix uteri (women and the malignant neoplasm of trachea, bronchus and lung correlate most closely (r=0.5915, followed by the malignant neoplasms (r=0.4832 of colon, rectosigmoid junction, rectum, anus and anal canal and lymphatic/haematopoietic tissue, the malignant neoplasms (r=-0.483 of stomach, and trachea, bronchus and lung, the malignant neoplasms (r=0.4605 of skin and prostate (men, the malignant neoplasms (r=0.4344 of colon, rectosigmoid junction, rectum, anus and anal canal and trachea, bronchus and lung, etc. These correlations are likely caused by common or adverse environmental, social, medical or even genetic / molecular factors.

  1. Hints of an axion-like particle mixing in the GeV gamma-ray blazar data?

    Energy Technology Data Exchange (ETDEWEB)

    Mena, Olga [IFIC, Universidad de Valencia-CSIC, E-46071, Valencia (Spain); Razzaque, Soebur, E-mail: omena@ific.uv.es, E-mail: srazzaque@uj.ac.za [Department of Physics, University of Johannesburg, PO Box 524, Auckland Park 2006 (South Africa)

    2013-11-01

    Axion-Like Particles (ALPs), if exist in nature, are expected to mix with photons in the presence of an external magnetic field. The energy range of photons which undergo strong mixing with ALPs depends on the ALP mass, on its coupling with photons as well as on the external magnetic field and particle density configurations. Recent observations of blazars by the Fermi Gamma-Ray Space Telescope in the 0.1–300 GeV energy range show a break in their spectra in the 1–10 GeV range. We have modeled this spectral feature for the flat-spectrum radio quasar 3C454.3 during its November 2010 outburst, assuming that a significant fraction of the gamma rays convert to ALPs in the large scale jet of this blazar. Using theoretically motivated models for the magnetic field and particle density configurations in the kiloparsec scale jet, outside the broad-line region, we find an ALP mass m{sub a} ∼ (1−3)⋅10{sup −7} eV and coupling g{sub aγ} ∼ (1−3)⋅10{sup −10} GeV{sup −1} after performing an illustrative statistical analysis of spectral data in four different epochs of emission. The precise values of m{sub a} and g{sub aγ} depend weakly on the assumed particle density configuration and are consistent with the current experimental bounds on these quantities. We apply this method and ALP parameters found from fitting 3C454.3 data to another flat-spectrum radio quasar PKS1222+216 (4C+21.35) data up to 400 GeV, as a consistency check, and found good fit. We find that the ALP-photon mixing effect on the GeV spectra may not be washed out for any reasonable estimate of the magnetic field in the intergalactic media.

  2. The hint protocol: Using a broadcast method to enable ID-free data transmission for dense IoT devices

    OpenAIRE

    Ren, Yi; Wu, Ren-Jie; Tseng, Yu-Chee

    2017-01-01

    IoT (Internet of Things) has attracted a lot of attention recently. IoT devices need to report their data or status to base stations at various frequencies. The IoT communications observed by a base station normally exhibit the following characteristics: (1) massively connected, (2) lightly loaded per packet, and (3) periodical or at least mostly predictable. The current design principals of communication networks, when applied to IoT scenarios, however, do not fit well to these requirements....

  3. Give me a hint: An ID-free small data transmission protocol for dense IoT devices

    OpenAIRE

    Ren, Yi; Wu, Ren-Jie; Huang, Teng-Wei; Tseng, Yu-Chee

    2017-01-01

    IoT (Internet of Things) has attracted a lot of attention recently. IoT devices need to report their data or status to base stations at various frequencies. The IoT communications observed by a base station normally exhibit the following characteristics: (1) massively connected, (2) lightly loaded per packet, and (3) periodical or at least mostly predictable. The current design principals of communication networks, when applied to IoT scenarios, however, do not fit well to these requirements....

  4. Special Issue: Very large eddy simulation. Issue Edited by Dimitris Drikakis.Copyright © 2002 John Wiley & Sons, Ltd.Save Title to My ProfileSet E-Mail Alert Previous Issue | Next Issue > Full Issue Listing-->Volume 39, Issue 9, Pages 763-864(30 July 2002)Research ArticleEmbedded turbulence model in numerical methods for hyperbolic conservation laws

    Science.gov (United States)

    Drikakis, D.

    2002-07-01

    The paper describes the use of numerical methods for hyperbolic conservation laws as an embedded turbulence modelling approach. Different Godunov-type schemes are utilized in computations of Burgers' turbulence and a two-dimensional mixing layer. The schemes include a total variation diminishing, characteristic-based scheme which is developed in this paper using the flux limiter approach. The embedded turbulence modelling property of the above methods is demonstrated through coarsely resolved large eddy simulations with and without subgrid scale models. Copyright

  5. Is Online Learning Suitable for All English Language Students?

    Science.gov (United States)

    Kuama, Settha; Intharaksa, Usa

    2016-01-01

    This study aimed to examine online language learning strategies (OLLS) used and affection in online learning of successful and unsuccessful online language students and investigate the relationships between OLLS use, affection in online learning and online English learning outcomes. The participants included 346 university students completing a…

  6. The Impetus Behind the Creation of the United States Naval Reserve

    Science.gov (United States)

    2005-06-17

    oll.libertyfund.org/Texts/Jefferson0136/Works/ Vol10 /0054-10_Pt04_1805.html; Internet; accessed 21 February, 2005. 17Henry Adams, History of the United...Vol. 10 (1803 – 1807). [book on-line] available from http://oll.libertyfund.org/Texts/Jefferson0136/Works/ Vol10 /0054- 10_Pt04_1805.html. Internet

  7. Differential metallothionein expression in oral lichen planus and amalgam-associated oral lichenoid lesions.

    Science.gov (United States)

    Mendes, G-G; Servato, J-P-S; Borges, F-C; Rosa, R-R; Siqueira, C-S; de Faria, P-R; Loyola, A-M; Cardoso, S-V

    2018-05-01

    Oral lichen planus (OLP) is a chronic inflammatory disease mediated by T cells, which manifests as reticular (white) or erosive (red) lesions, that are eventually painful. Oral lichenoid lesion (OLL) are distinguished from OLP by the presence of precipitating factors. The aim of this study was to evaluate whether the presence of metallothionein, which is involved in anti-apoptotic pathways and the anti-oxidative response, could serve as a differential diagnostic for OLP and OLL. We evaluated the expression of metallothionein in 40 cases of OLP and 20 cases of OLL using immunohistochemistry. White OLP has higher concentrations of metallothionein than red OLP in basal and parabasal layers. Moreover, metallothionein was more frequently observed in the cytoplasm and nuclei of basal cells in OLP patients compared to the same regions of OLL cases. Metallothionein levels are related to OLP severity and may contribute to a differential diagnosis between OLP and OLL.

  8. Filaggrin gene mutations and the distribution of filaggrin in oral mucosa of patients with oral lichen planus and healthy controls.

    Science.gov (United States)

    Larsen, K R; Johansen, J D; Reibel, J; Zachariae, C; Rosing, K; Pedersen, A M L

    2017-05-01

    Lichen planus (LP) is a chronic inflammatory disease of unknown aetiology affecting the skin and oral mucosa. Oral lichenoid lesions (OLLs), like oral contact reactions, may resemble oral lichen planus (OLP) both clinically and histopathologically. As OLP and OLL are hyperkeratotic diseases and filaggrin is essential to keratinization, the distribution of filaggrin may be altered in these lesions. To investigate whether patients with OLP/OLL have (i) altered distribution of filaggrin in the oral mucosa; (ii) a higher incidence of mutations in the filaggrin gene (FLG); (iii) active dermatoses, apart from cutaneous LP, than healthy controls; and (iv) patients with OLP/OLL and a defect in the FLG have more widespread oral lesions and report more symptoms than OLP/OLL patients without a concomitant defect in the FLG. Forty-nine Caucasian patients (42 women and 7 men, mean age 61.0 ± 10.3 years), with symptomatic OLP, OLL or stomatitis, and 29 matched healthy controls underwent a clinical oral and dermatological examination, oral mucosal biopsy and filaggrin genotyping (testing for R2447X, R501X, 2282del4). Smear tests for Candida spp. were performed in all patients to exclude oral candidiasis. Immunohistochemistry were performed using poly- and monoclonal filaggrin antibodies. The immunoreactivity for filaggrin was significantly more intense in the oral mucosa in the patients with OLP/OLL compared with healthy controls (P = 0.000025). No difference was noted in the incidence of defects in the FLG and active dermatoses between patients and healthy controls. No difference was noted in extension and number of symptoms reported by patients with OLP/OLL with or without a concomitant defect in the FLG. OLP/OLL is associated with an altered distribution of filaggrin in the oral mucosa independently of defects in the FLG. Patients with OLP/OLL did not display more active dermatoses other than cutaneous LP when compared to healthy controls. © 2016 European Academy of

  9. High percentage of oral lichen planus and lichenoid lesion in oral squamous cell carcinomas.

    Science.gov (United States)

    Ruokonen, Hellevi M A; Juurikivi, Aino; Kauppila, Timo; Heikkinen, Anna Maria; Seppänen-Kaijansinkko, Riitta

    2017-08-01

    Oral lichen planus (OLP) and lichenoid lesions (OLL) are regarded as precursor lesions of oral squamous cell carcinoma (OSCC) with potential for malignant transformation. This potential is not clear due to difficulties in diagnosis of OLP and OLL. Our aim was therefore to evaluate previously identified OLP and OLL as precursor lesions in OSCC and to identify cancer related etiological factors such as smoking and alcohol consumption. We retrospectively reviewed all cases (total 323, comprising 164 females and 159 males) with OSCC treated at the Department of Oral and Maxillofacial Diseases and Surgery, Helsinki University Hospital during 2015. Confirmed by histopathological biopsy, 58 (17.9%) had OLP and 13 had OLL (4.0%) as precursor lesion. Patients with OLP were slightly older than those without it. OLP was more common in females than in males (p < .0001). TN class 1 tumors were more prevalent among patients with OLP or OLL (p = .006) and cancer relapses less common (p = .005). Smoking was less frequent in patients with OLP and OLL (p < .0001). Also alcohol abuse was less frequent among these patients (p < .001). Our findings confirm the importance of active follow-up of all patients with OLP and OLL even in patients who do not fit a traditional high-risk category for OSCC.

  10. Changes in optical characteristics of surface microlayers hint to photochemically and microbially-mediated DOM turnover in the upwelling region off Peru

    Science.gov (United States)

    Galgani, L.; Engel, A.

    2015-12-01

    The coastal upwelling system off Peru is characterized by high biological activity and a pronounced subsurface oxygen minimum zone, as well as associated emissions of atmospheric trace gases such as N2O, CH4 and CO2. During the Meteor (M91) cruise to the Peruvian upwelling system in 2012, we investigated the composition of the sea-surface microlayer (SML), the oceanic uppermost boundary directly subject to high solar radiation, often enriched in specific organic compounds of biological origin like Chromophoric Dissolved Organic Matter (CDOM) and marine gels. In the SML, the continuous photochemical and microbial recycling of organic matter may strongly influence gas exchange between marine systems and the atmosphere. In order to understand organic matter cycling in surface films, we analyzed SML and underlying water samples at 38 stations determining DOC concentration, amino acid composition, marine gels, CDOM and bacterial and phytoplankton abundance as indicators of photochemical and microbial alteration processes. CDOM composition was characterized by spectral slope (S) values and Excitation-Emission Matrix fluorescence (EEMs), which allow to track changes in molecular weight (MW) of DOM, and to determine potential DOM sources and sinks. We identified five fluorescent components of the CDOM pool, of which two had excitation/emission characteristics of protein-like fluorophores and were highly enriched in the SML. CDOM composition and changes in spectral slope properties suggested a local microbial release of HMW DOM directly in the SML as a response to light exposure in this extreme environment. Our results suggest that microbial and photochemical processes play an important role for the production, alteration and loss of optically active substances in the SML.

  11. Changes in optical characteristics of surface microlayers in the Peruvian upwelling region hint to photochemically and microbially-mediated DOM turnover

    Science.gov (United States)

    Engel, A.; Galgani, L.

    2016-02-01

    The coastal upwelling system off Peru is characterized by high biological activity and associated subsurface oxygen minimum zone, leading to an enhanced emission of atmospheric trace gases. High biological productivity in the water column may promote the establishment of enriched organic surface films, key environments for processes regulating gas fluxes across the water-air interface. During M91 cruise to the Peruvian upwelling, we focused our attention on the composition of the sea-surface microlayer (SML), the oceanic uppermost boundary directly subject to high solar radiation, often enriched in specific organic compounds of biological origin like Chromophoric Dissolved Organic Matter (CDOM) and marine gels. In the SML, the continuous photochemical and microbial recycling of organic matter may strongly influence gas exchange between marine systems and the atmosphere. In order to understand organic matter cycling in surface films, we analyzed SML and underlying water samples in 38 stations determining DOC concentrations, amino acids composition, marine gels, CDOM and bacterial abundance as indicators of photochemical and microbial alteration processes. CDOM composition was characterized by spectral slopes (S) values and Excitation-Emission Matrix fluorescence (EEMs), which allow to track changes in molecular weight (MW) of DOM, and to determine potential DOM sources. Profound changes in spectral slope properties were observed suggesting smaller MW CDOM in the SML compared to underlying water. Microbial and photochemical degradation are likely the main drivers for organic matter cycling in the top layer of the ocean. Consequences on the formation of inorganic and organic species highly relevant for air-sea gas exchange and for climate dynamics will be discussed.

  12. Comparative expression profiling of AtRAD5B and AtNDL1: Hints towards a role in G protein mediated signaling.

    Science.gov (United States)

    Khatri, Nisha; Singh, Swati; Hakim, Nasmeen; Mudgil, Yashwanti

    2017-11-01

    Arabidopsis AtRAD5B encodes for a putative helicase of the class SWItch/Sucrose Non-Fermentable (SWI/SNF) ATPases. We identified AtRAD5B as an interactor of N-MYC DOWNREGULATED-LIKE1 (AtNDL1) in a yeast two-hybrid screen. AtNDL1 is a G protein signaling component which regulates auxin transport and gradients together with GTP binding protein beta 1 (AGB1). Auxin gradients are known to recruit SWI/SNF remodeling complexes to the chromatin and regulate expression of genes involved in flower and leaf formation. In current study, a comparative spatial and temporal co-expression/localization analysis of AtNDL1, AGB1 with AtRAD5B was carried out in order to explore the possibility of their coexistence in a common signaling network. Translational fusion (GUS) of AtNDL1 and AtRAD5B in seedlings and reproductive organs revealed that both shared similar expression patterns with the highest expression observed in male reproductive organs. Moreover, they shared similar domains of localization in roots, suggesting their potential functioning together in reproductive and root development processes. This study predicts the existence of a signaling network involving AtNDL1, AGB1 with AtRAD5B. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. The 2012-2016 eruptive cycle at Copahue volcano (Argentina) versus the peripheral gas manifestations: hints from the chemical and isotopic features of fumarolic fluids

    Science.gov (United States)

    Tassi, F.; Agusto, M.; Lamberti, C.; Caselli, A. T.; Pecoraino, G.; Caponi, C.; Szentiványi, J.; Venturi, S.; Vaselli, O.

    2017-10-01

    This study presents the chemical and isotopic compositions of hydrothermal gases from fumaroles discharging around Copahue volcano (Argentina). Gas samples, including those from two fumaroles at the active summit crater, were collected during 13 surveys carried out by different research teams from 1976 to February 2016. The time-series of H2, CO and light hydrocarbons showed episodic increases related to the main events of the last eruptive cycle that started on 19 July 2012. Concentration peaks were likely caused by enhanced input of hot magmatic fluids affecting the hydrothermal reservoir. These data contrast with the temporal variations shown by Rc/ Ra and δ13C-CO2 values in 2012-2014, which indicated an increasing input from a crustal fluid source. In 2015-2016, however, these isotopic parameters showed opposite trends; their composition became closer to that of the two summit fumaroles, which possibly corresponds to that of the deep magmatic-related end-member. The delayed and reduced compositional changes in the peripheral hydrothermal fluid discharge in response to the 2012-2016 eruptive events suggest that geochemical surveys of these emissions are unlikely to provide premonitory signals of volcanic unrest if the volcanic activity remains centered in the main crater. Instead, an instrument which is able to provide measurements of volcanic gases in the air (e.g. MultiGAS) may be used to detect changes at the summit crater. Otherwise, monitoring of seismic activity and ground deformation, as well as the periodic measurement of the chemistry of the water in the Rio Agrio, which is fed by thermal discharge from the summit crater, seem to represent the most reliable means of monitoring at Copahue. However, the relative compositional stability of the hydrothermal reservoir is a great advantage in terms of geothermal resource exploitation and could encourage new investments in the Copahue geothermal project which was abandoned in the 1990s.

  14. A new look inside planetary nebula LoTr 5: a long-period binary with hints of a possible third component

    Science.gov (United States)

    Aller, A.; Lillo-Box, J.; Vučković, M.; Van Winckel, H.; Jones, D.; Montesinos, B.; Zorotovic, M.; Miranda, L. F.

    2018-05-01

    LoTr 5 is a planetary nebula with an unusual long-period binary central star. As far as we know, the pair consists of a rapidly rotating G-type star and a hot star, which is responsible for the ionization of the nebula. The rotation period of the G-type star is 5.95 d and the orbital period of the binary is now known to be ˜2700 d, one of the longest in central star of planetary nebulae. The spectrum of the G central star shows a complex H α double-peaked profile which varies with very short time-scales, also reported in other central stars of planetary nebulae and whose origin is still unknown. We present new radial velocity observations of the central star which allow us to confirm the orbital period for the long-period binary and discuss the possibility of a third component in the system at ˜129 d to the G star. This is complemented with the analysis of archival light curves from Super Wide Angle Search for Planets, All Sky Automated Survey, and Optical Monitoring Camera. From the spectral fitting of the G-type star, we obtain an effective temperature of Teff = 5410 ± 250 K and surface gravity of log g = 2.7 ± 0.5, consistent with both giant and subgiant stars. We also present a detailed analysis of the H α double-peaked profile and conclude that it does not present correlation with the rotation period and that the presence of an accretion disc via Roche lobe overflow is unlikely.

  15. Exploring the predictive value of the evoked potentials score in MS within an appropriate patient population: a hint for an early identification of benign MS?

    Directory of Open Access Journals (Sweden)

    Margaritella Nicolò

    2012-08-01

    Full Text Available Abstract Background The prognostic value of evoked potentials (EPs in multiple sclerosis (MS has not been fully established. The correlations between the Expanded Disability Status Scale (EDSS at First Neurological Evaluation (FNE and the duration of the disease, as well as between EDSS and EPs, have influenced the outcome of most previous studies. To overcome this confounding relations, we propose to test the prognostic value of EPs within an appropriate patient population which should be based on patients with low EDSS at FNE and short disease duration. Methods We retrospectively selected a sample of 143 early relapsing remitting MS (RRMS patients with an EDSS Results The Evoked Potentials score (EP score and the Time to EDSS 2.0 (TT2 were the best predictors of worsening in our sample (Odds Ratio 1.10 and 0.82 respectively, p=0.001. Low EP score (below 15–20 points, short TT2 (lower than 3–5 years and their interaction resulted to be the most useful for the identification of worsening patterns. Moreover, in patients with an EP score at FNE below 6 points and a TT2 greater than 3 years the probability of worsening was 10% after 4–5 years and rapidly decreased thereafter. Conclusions In an appropriate population of early RRMS patients, the EP score at FNE is a good predictor of disability at low values as well as in combination with a rapid buildup of disability. Interestingly, an EP score at FNE under the median together with a clinical stability lasting more than 3 years turned out to be a protective pattern. This finding may contribute to an early identification of benign patients, well before the term required to diagnose Benign MS (BMS.

  16. The human interactome knowledge base (hint-kb): An integrative human protein interaction database enriched with predicted protein–protein interaction scores using a novel hybrid technique

    KAUST Repository

    Theofilatos, Konstantinos A.; Dimitrakopoulos, Christos M.; Likothanassis, Spiridon D.; Kleftogiannis, Dimitrios A.; Moschopoulos, Charalampos N.; Alexakos, Christos; Papadimitriou, Stergios; Mavroudi, Seferina P.

    2013-01-01

    Proteins are the functional components of many cellular processes and the identification of their physical protein–protein interactions (PPIs) is an area of mature academic research. Various databases have been developed containing information about

  17. Tüüne-Kristin & Urmo Vaikla : "Oleme mõlemad friigid. Kaitseme oma nägemust mõistliku ajalimiidini" / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Tüüne-Kristin ja Urmo Vaikla interjööri olulistest osadest, harmooniast sisekujunduses, sellest, mida peaks kodu omanikule pakkuma jm. T.-K. ja U. Vaiklast, esinemised näitustel, olulisemate kujundatud ühiskondlike ruumide nimistu, omistatud preemia. 1992. aastast töötavad mõlemad Vaikla Stuudios. Ill.: värv. foto T.-K. ja U. Vaiklast

  18. Examining the Role of Ideological and Political Education on University Students' Civic Perceptions and Civic Participation in Mainland China: Some Hints from Contemporary Citizenship Theory

    Science.gov (United States)

    Zhang, Chong; Fagan, Catherine

    2016-01-01

    A long existing compulsive curriculum of ideological and political education is employed by the Chinese government to promote citizenship education among Chinese university students. This article builds on the findings of a mixed-methods research that examined the role of ideological and political education on university students' civic…

  19. Cesium accumulation by bacterium Thermus sp.TibetanG7: hints for biomineralization of cesiumbearing geyserite in hot springs in Tibet, China

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The bacterium Thermus sp. TibetanG7, isolated from hot springs in Tibet, China, was examined for the ability to accumulate cesium from solutions. Environmental conditions were simulated and the effects of pH, K+, Na+ and K+-regimes were then studied to determine the possible role of the bacterium in the formation of cesium-bearing geyserite around these hot springs. In despite of the inhibition of K+ and Na+, the bacterium Thermus sp. TibetanG7 revealed noticeable accumulation of cesium from solutions, with maximum accumulations of 53.49 and 40.41 μmol Cesium/g cell dry weight in Na+ and K+ inhibition experiments, respectively. The accumulation of cesium by this microorganism is rapid, with 40%―50% accumulated within the first 5 min. K+-deficient cells showed a much higher capacity of cesium accumulation compared with K+-sufficient cells. It is evident that the bacteria within the genus thermus play a significant role in the cesium assembly. The formation of cesium-bearing geyserite is also considered.

  20. HINTW, a W-chromosome HINT gene in chick, is expressed ubiquitously and is a robust female cell marker applicable in intraspecific chimera studies.

    Science.gov (United States)

    Nagai, Hiroki; Sezaki, Maiko; Bertocchini, Federica; Fukuda, Kimiko; Sheng, Guojun

    2014-05-01

    Grafting and transplantation experiments in embryology require proper distinction between host and donor tissues. For the avian model this has traditionally been achieved by using two closely related species (e.g., chick and quail) followed by species-specific antibody staining. Here, we show that an in situ hybridization probe against the HINTW gene is a robust and reliable marker for female-derived chicken cells. At all pre-circulation stages tested, all cells in female embryos, independently confirmed by PCR analysis, were strongly positive for HINTW, whereas all male embryos were negative. This probe is broadly applicable in intra-specific chick/chick chimera studies, and as a proof of principle, we utilized this probe to detect female cells in three experimental settings: (1) to mark female donor cells in a node transplantation assay; (2) to distinguish female cells in male/female twins generated by the Cornish pasty culture; and (3) to detect female half of the embryo in artificially generated bilateral gynandromorphs. A rapid, PCR based pre-screening step increases the efficiency of obtaining desired donor/host sex combination from 25% to 100%. For most avian chimera studies, this female-specific in situ probe is a low cost alternative to the commonly used QCPN antibody and to ubiquitous-GFP chicken strains which are not widely available to the research community. © 2014 Wiley Periodicals, Inc.

  1. The Run Control System and the Central Hint and Information Processor of the Data Acquisition System of the ATLAS Experiment at the LHC

    CERN Document Server

    Anders, G; The ATLAS collaboration; Lehmann Miotto, G; Magnoni, L

    2014-01-01

    The Trigger and Data Acquisition (TDAQ) system of the ATLAS detector is composed of a large number of distributed hardware and software components (about 3000 machines and more than 15000 concurrent processes at the end of LHC’s Run I) which in a coordinated manner provide the data-taking functionality of the overall system. The Run Control (RC) system steers the data acquisition by starting and stopping processes and by carrying all data-taking elements through well-defined states in a coherent way (finite state machine pattern). The RC is organized as a hierarchical tree (run control tree) of run controllers following the functional de-composition into systems and sub-systems of the ATLAS detector. During the LHC Long Shutdown 1 (LS1) the RC has been completely re-designed and re-implemented in order to better fulfill the new requirements which emerged during the LHC Run 1 and were not foreseen during the initial design phase, and in order to improve the error management and recovery mechanisms. Indeed gi...

  2. Changes in optical characteristics of surface microlayers hint to photochemically and microbially mediated DOM turnover in the upwelling region off the coast of Peru

    Science.gov (United States)

    Galgani, Luisa; Engel, Anja

    2016-04-01

    The coastal upwelling system off the coast of Peru is characterized by high biological activity and a pronounced subsurface oxygen minimum zone, as well as associated emissions of atmospheric trace gases such as N2O, CH4 and CO2. From 3 to 23 December 2012, R/V Meteor (M91) cruise took place in the Peruvian upwelling system between 4.59 and 15.4° S, and 82.0 to 77.5° W. During M91 we investigated the composition of the sea-surface microlayer (SML), the oceanic uppermost boundary directly subject to high solar radiation, often enriched in specific organic compounds of biological origin like chromophoric dissolved organic matter (CDOM) and marine gels. In the SML, the continuous photochemical and microbial recycling of organic matter may strongly influence gas exchange between marine systems and the atmosphere. We analyzed SML and underlying water (ULW) samples at 38 stations focusing on CDOM spectral characteristics as indicator of photochemical and microbial alteration processes. CDOM composition was characterized by spectral slope (S) values and excitation-emission matrix fluorescence (EEMs), which allow us to track changes in molecular weight (MW) of DOM, and to determine potential DOM sources and sinks. Spectral slope S varied between 0.012 to 0.043 nm-1 and was quite similar between SML and ULW, with no significant differences between the two compartments. Higher S values were observed in the ULW of the southern stations below 15° S. By EEMs, we identified five fluorescent components (F1-5) of the CDOM pool, of which two had excitation/emission characteristics of amino-acid-like fluorophores (F1, F4) and were highly enriched in the SML, with a median ratio SML : ULW of 1.5 for both fluorophores. In the study region, values for CDOM absorption ranged from 0.07 to 1.47 m-1. CDOM was generally highly concentrated in the SML, with a median enrichment with respect to the ULW of 1.2. CDOM composition and changes in spectral slope properties suggested a local microbial release of DOM directly in the SML as a response to light exposure in this extreme environment. In a conceptual model of the sources and modifications of optically active DOM in the SML and underlying seawater (ULW), we describe processes we think may take place (Fig. 1); the production of CDOM of higher MW by microbial release through growth, exudation and lysis in the euphotic zone, includes the identified fluorophores (F1, F2, F3, F4, F5). Specific amino-acid-like fluorophores (F1, F4) accumulate in the SML with respect to the ULW, as photochemistry may enhance microbial CDOM release by (a) photoprotection mechanisms and (b) cell-lysis processes. Microbial and photochemical degradation are potential sinks of the amino-acid-like fluorophores (F1, F4), and potential sources of reworked and more refractory humic-like components (F2, F3, F5). In the highly productive upwelling region along the Peruvian coast, the interplay of microbial and photochemical processes controls the enrichment of amino-acid-like CDOM in the SML. We discuss potential implications for air-sea gas exchange in this area.

  3. A three-dimensional morphometric analysis of upper forelimb morphology in the enigmatic tapir (Perissodactyla: Tapirus) hints at subtle variations in locomotor ecology.

    Science.gov (United States)

    MacLaren, Jamie A; Nauwelaerts, Sandra

    2016-11-01

    Forelimb morphology is an indicator for terrestrial locomotor ecology. The limb morphology of the enigmatic tapir (Perissodactyla: Tapirus) has often been compared to that of basal perissodactyls, despite the lack of quantitative studies comparing forelimb variation in modern tapirs. Here, we present a quantitative assessment of tapir upper forelimb osteology using three-dimensional geometric morphometrics to test whether the four modern tapir species are monomorphic in their forelimb skeleton. The shape of the upper forelimb bones across four species (T. indicus; T. bairdii; T. terrestris; T. pinchaque) was investigated. Bones were laser scanned to capture surface morphology and 3D landmark analysis was used to quantify shape. Discriminant function analyses were performed to reveal features which could be used for interspecific discrimination. Overall our results show that the appendicular skeleton contains notable interspecific differences. We demonstrate that upper forelimb bones can be used to discriminate between species (>91% accuracy), with the scapula proving the most diagnostic bone (100% accuracy). Features that most successfully discriminate between the four species include the placement of the cranial angle of the scapula, depth of the humeral condyle, and the caudal deflection of the olecranon. Previous studies comparing the limbs of T. indicus and T. terrestris are corroborated by our quantitative findings. Moreover, the mountain tapir T. pinchaque consistently exhibited the greatest divergence in morphology from the other three species. Despite previous studies describing tapirs as functionally mediportal in their locomotor style, we find osteological evidence suggesting a spectrum of locomotor adaptations in the tapirs. We conclude that modern tapir forelimbs are neither monomorphic nor are tapirs as conserved in their locomotor habits as previously described. J. Morphol. 277:1469-1485, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  4. Frequent induction of chromosomal aberrations in in vivo skin fibroblasts after allogeneic stem cell transplantation: hints to chromosomal instability after irradiation

    International Nuclear Information System (INIS)

    Massenkeil, G.; Zschieschang, P.; Thiel, G.; Hemmati, P. G.; Budach, V.; Dörken, B.; Pross, J.; Arnold, R.

    2015-01-01

    Total body irradiation (TBI) has been part of standard conditioning regimens before allogeneic stem cell transplantation for many years. Its effect on normal tissue in these patients has not been studied extensively. We studied the in vivo cytogenetic effects of TBI and high-dose chemotherapy on skin fibroblasts from 35 allogeneic stem cell transplantation (SCT) patients. Biopsies were obtained prospectively (n = 18 patients) before, 3 and 12 months after allogeneic SCT and retrospectively (n = 17 patients) 23–65 months after SCT for G-banded chromosome analysis. Chromosomal aberrations were detected in 2/18 patients (11 %) before allogeneic SCT, in 12/13 patients (92 %) after 3 months, in all patients after 12 months and in all patients in the retrospective group after allogeneic SCT. The percentage of aberrant cells was significantly higher at all times after allogeneic SCT compared to baseline analysis. Reciprocal translocations were the most common aberrations, but all other types of stable, structural chromosomal aberrations were also observed. Clonal aberrations were observed, but only in three cases they were detected in independently cultured flasks. A tendency to non-random clustering throughout the genome was observed. The percentage of aberrant cells was not different between patients with and without secondary malignancies in this study group. High-dose chemotherapy and TBI leads to severe chromosomal damage in skin fibroblasts of patients after SCT. Our long-term data suggest that this damage increases with time, possibly due to in vivo radiation-induced chromosomal instability

  5. Human mtDNA hypervariable regions, HVR I and II, hint at deep common maternal founder and subsequent maternal gene flow in Indian population groups.

    Science.gov (United States)

    Sharma, Swarkar; Saha, Anjana; Rai, Ekta; Bhat, Audesh; Bamezai, Ramesh

    2005-01-01

    We have analysed the hypervariable regions (HVR I and II) of human mitochondrial DNA (mtDNA) in individuals from Uttar Pradesh (UP), Bihar (BI) and Punjab (PUNJ), belonging to the Indo-European linguistic group, and from South India (SI), that have their linguistic roots in Dravidian language. Our analysis revealed the presence of known and novel mutations in both hypervariable regions in the studied population groups. Median joining network analyses based on mtDNA showed extensive overlap in mtDNA lineages despite the extensive cultural and linguistic diversity. MDS plot analysis based on Fst distances suggested increased maternal genetic proximity for the studied population groups compared with other world populations. Mismatch distribution curves, respective neighbour joining trees and other statistical analyses showed that there were significant expansions. The study revealed an ancient common ancestry for the studied population groups, most probably through common founder female lineage(s), and also indicated that human migrations occurred (maybe across and within the Indian subcontinent) even after the initial phase of female migration to India.

  6. Hint of a Universal Law for the Financial Gains of Competitive Sport Teams. The Case of Tour de France Cycle Race

    Directory of Open Access Journals (Sweden)

    Marcel Ausloos

    2017-12-01

    Full Text Available This short note is intended as a “Letter to the Editor” Perspective in order that it serves as a contribution, in view of reaching the physics community caring about rare events and scaling laws and unexpected findings, on a domain of wide interest: sport and money. It is apparent from the data reported and discussed below that the scarcity of such data does not allow to recommend a complex elaboration of an agent based model,—at this time. In some sense, this also means that much data on sport activities is not necessarily given in terms of physics prone materials, but it could be, and would then attract much attention. Nevertheless the findings tie the data to well-known scaling laws and physics processes. It is found that a simple scaling law describes the gains of teams in recent bicycle races, like the Tour de France. An analogous case, ranking teams in Formula 1 races, is shown in an Appendix.

  7. The role of insulin C-peptide in the coevolution analyses of the insulin signaling pathway: a hint for its functions.

    Directory of Open Access Journals (Sweden)

    Shuai Wang

    Full Text Available As the linker between the A chain and B chain of proinsulin, C-peptide displays high variability in length and amino acid composition, and has been considered as an inert byproduct of insulin synthesis and processing for many years. Recent studies have suggested that C-peptide can act as a bioactive hormone, exerting various biological effects on the pathophysiology and treatment of diabetes. In this study, we analyzed the coevolution of insulin molecules among vertebrates, aiming at exploring the evolutionary characteristics of insulin molecule, especially the C-peptide. We also calculated the correlations of evolutionary rates between the insulin and the insulin receptor (IR sequences as well as the domain-domain pairs of the ligand and receptor by the mirrortree method. The results revealed distinctive features of C-peptide in insulin intramolecular coevolution and correlated residue substitutions, which partly supported the idea that C-peptide can act as a bioactive hormone, with significant sequence features, as well as a linker assisting the formation of mature insulin during synthesis. Interestingly, the evolution of C-peptide exerted the highest correlation with that of the insulin receptor and its ligand binding domain (LBD, implying a potential relationship with the insulin signaling pathway.

  8. Hints of supernova debris deposition on the lunar surface: {sup 60}Fe and {sup 53}Mn measurements by means of accelerator mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Fimiani, Leticia; Faestermann, Thomas; Gomez Guzman, Jose Manuel; Hain, Karin; Korschinek, Gunther; Ludwig, Peter [Physik Department, Technische Universitaet Muenchen, Garching (Germany); Herzog, Gregory; Ligon, Bret; Park, Jisun [Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ (United States); Rugel, Georg [Forschungszentrum Dresden Rossendorf, Dresden (Germany)

    2013-07-01

    The enhanced concentration of {sup 60}Fe in a deep ocean ferro-manganese crust about (2.1±0.4) Myr old (Fitoussi et al., PRL 101, 121101 (2008)), suggests that one or more supernova (SN) explosions occurred in the vicinity of the Solar System. That observation was only possible with the ultra sensitive Accelerator Mass Spectrometry (AMS) technique at the Maier-Leibnitz-Laboratorium in Munich, where we are able to measure concentrations of {sup 60}Fe/Fe down to a level of 10{sup -16}. Because of its lacking atmosphere and negligible sedimentation rate, the Lunar surface is an excellent quantitative reservoir for SN debris. We searched for live {sup 60}Fe and {sup 53}Mn in samples from 3 Apollo missions. {sup 53}Mn is, similar as {sup 26}Al and {sup 60}Fe, a tool to trace nucleosynthesis activities. It is formed primarily during the explosive silicon-burning of the inner shells of SNe via {sup 53}Fe which β-decays to {sup 53}Mn with an 8.51 min half-life. Samples where we found an enhanced {sup 60}Fe concentration showed also an enhancement of {sup 53}Mn. If confirmed, this could be the first detection of live {sup 53}Mn originating from nucleosynthesis.

  9. La Cruzada de los Niños: Memoria, Actualidad y Guiños Históricos The Children's Crusade: Memory, Present Times and Historical Hints

    Directory of Open Access Journals (Sweden)

    Patricio Rodríguez-Plaza

    2010-12-01

    Full Text Available El presente texto se ubica en el supuesto lugar de un espectador ordinario, escudriña críticamente en las problemáticas que expresa y expone la obra La cruzada de los niños, menos desde el texto dramático que desde las dimensiones espectaculares que dotan y construyen sentido teatral: escenografía, vestuario, iluminación, diseño sonoro.The following is a text that, placing itself in the spot of a regular spectator, critically examines the problematical issues immersed in the play La Cruzada de los Niños. The text will construct the analysis using mainly the dimensions of the spectacle that build up a theatrical sense rather than focusing only on the play's text. It will consider elements such as the scenography, costume design, lighting, and theatrical acoustics.

  10. Central-engine-powered Bright X-Ray Flares in Short Gamma-Ray Bursts: A Hint of a Black Hole–Neutron Star Merger?

    Science.gov (United States)

    Mu, Hui-Jun; Gu, Wei-Min; Mao, Jirong; Hou, Shu-Jin; Lin, Da-Bin; Liu, Tong

    2018-05-01

    Short gamma-ray bursts may originate from the merger of a double neutron star (NS) or the merger of a black hole (BH) and an NS. We propose that the bright X-ray flare related to the central engine reactivity may indicate a BH–NS merger, since such a merger can provide more fallback materials and therefore a more massive accretion disk than the NS–NS merger. Based on the 49 observed short bursts with the Swift/X-ray Telescope follow-up observations, we find that three bursts have bright X-ray flares, among which three flares from two bursts are probably related to the central engine reactivity. We argue that these two bursts may originate from the BH–NS merger rather than the NS–NS merger. Our suggested link between the central-engine-powered bright X-ray flare and the BH–NS merger event can be checked by future gravitational wave detections from advanced LIGO and Virgo.

  11. Distribution patterns of the cold adapted bumblebee Bombus alpinus in the Alps and hints of an uphill shift (Insecta: Hymenoptera: Apidae)

    Czech Academy of Sciences Publication Activity Database

    Biella, Paolo; Bogliani, G.; Cornalba, M.; Manino, A.; Neumayer, J.; Porporato, M.; Rasmont, P.; Milanesi, P.

    2017-01-01

    Roč. 21, č. 2 (2017), s. 357-366 ISSN 1366-638X R&D Projects: GA ČR(CZ) GP14-10035P Grant - others:GA JU(CZ) 152/2016/P Institutional support: RVO:60077344 Keywords : climate change * specialist * rare species Subject RIV: EH - Ecology, Behaviour OBOR OECD: Ecology Impact factor: 1.462, year: 2016 https://link.springer.com/article/10.1007/s10841-017-9983-1

  12. Binding Characteristics of Sphingosine-1-Phosphate to ApoM hints to Assisted Release Mechanism via the ApoM Calyx-Opening

    Science.gov (United States)

    Zhang, Hansi; Pluhackova, Kristyna; Jiang, Zhenyan; Böckmann, Rainer A.

    2016-08-01

    Sphingosine-1-phosphate (S1P) is a lysophospholipid mediator carried by the HDL-associated apoM protein in blood, regulating many physiological processes by activating the G protein-coupled S1P receptor in mammals. Despite the solved crystal structure of the apoM-S1P complex, the mechanism of S1P release from apoM as a part of the S1P pathway is unknown. Here, the dynamics of the wild type apoM-S1P complex as well as of mutants were investigated by means of atomistic molecular dynamics simulations. The potential of mean force for S1P unbinding from apoM reflected a large binding strength of more than 60 kJ/mol. This high unbinding free energy for S1P underlines the observed specificity of the physiological effects of S1P as it suggests that the spontaneous release of S1P from apoM is unlikely. Instead, S1P release and thus the control of this bioactive lipid probably requires the tight interaction with other molecules, e.g. with the S1P receptor. Mutations of specific S1P anchoring residues of apoM decreased the energetic barrier by up to 20 kJ/mol. Moreover, the ligand-free apoM protein is shown to adopt a more open upper hydrophilic binding pocket and to result in complete closure of the lower hydrophobic cavity, suggesting a mechanism for adjusting the gate for ligand access.

  13. The first toxicological study of the antiozonant and research tool ethylene diurea (EDU) using a Lemna minor L. bioassay: Hints to its mode of action.

    Science.gov (United States)

    Agathokleous, Eugenios; Mouzaki-Paxinou, Akrivi-Chara; Saitanis, Costas J; Paoletti, Elena; Manning, William J

    2016-06-01

    The antiozonant and research tool ethylene diurea (EDU) is widely studied as a phytoprotectant against the widespread pollutant ground-surface ozone. Although it has been extensively used, its potential toxicity in the absence of ozone is unknown and its mode of action is unclear. The purpose of this research was to toxicologically assess EDU and to further investigate its mode of action using Lemna minor L. as a model organism. Application of EDU concentrations greater than 593 mg L(-1) (practically 600 mg L(-1)) resulted in adverse inhibition of colony growth. As no-observed-toxic-effects concentration (NOEL) we recommend a concentration of 296 mg L(-1) (practically 300 mg L(-1)). A hormetic response was detected, i.e. stimulatory effects of low EDU concentrations, which may indicate overcompensation in response to disruption in homeostasis. Growth inhibition and suppressed biomass were associated with impacted chlorophyll a fluorescence (ΦPSII, qP and ETR). Furthermore, EDU increased mesophyll thickness, as indicated by frond succulence index. Applications of concentrations ≥593 mg L(-1) to uncontrolled environments should be avoided due to potential toxicity to sensitive organisms and the environment. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. The first toxicological study of the antiozonant and research tool ethylene diurea (EDU) using a Lemna minor L. bioassay: Hints to its mode of action

    International Nuclear Information System (INIS)

    Agathokleous, Eugenios; Mouzaki-Paxinou, Akrivi-Chara; Saitanis, Costas J.; Paoletti, Elena; Manning, William J.

    2016-01-01

    The antiozonant and research tool ethylene diurea (EDU) is widely studied as a phytoprotectant against the widespread pollutant ground-surface ozone. Although it has been extensively used, its potential toxicity in the absence of ozone is unknown and its mode of action is unclear. The purpose of this research was to toxicologically assess EDU and to further investigate its mode of action using Lemna minor L. as a model organism. Application of EDU concentrations greater than 593 mg L −1 (practically 600 mg L −1 ) resulted in adverse inhibition of colony growth. As no-observed-toxic-effects concentration (NOEL) we recommend a concentration of 296 mg L −1 (practically 300 mg L −1 ). A hormetic response was detected, i.e. stimulatory effects of low EDU concentrations, which may indicate overcompensation in response to disruption in homeostasis. Growth inhibition and suppressed biomass were associated with impacted chlorophyll a fluorescence (Φ PSII , q P and ETR). Furthermore, EDU increased mesophyll thickness, as indicated by frond succulence index. Applications of concentrations ≥593 mg L −1 to uncontrolled environments should be avoided due to potential toxicity to sensitive organisms and the environment. - Highlights: • The EDU concentration of 300 mg L −1 should be considered as NOEL. • EDU concentrations ≥600 mg L −1 should not be applied to uncontrolled environments. • Hormetic responses indicate overcompensation in response to homeostasis disruption. - Ethylene diurea is not toxic to sensitive organisms when applied at low concentrations (practically < 600 mg L −1 ).

  15. Clustering of malaria treatment failure (TF) in Daraweesh: hints for host genetic susceptibility to TF with emphasis on immune-modulating SNPs

    DEFF Research Database (Denmark)

    Giha, Hayder A; ElGhazali, Gehad; Nasr, Amre

    2010-01-01

    In malaria, drug resistance and treatment failure (TF) are not synonymous, although are escalating together. Over 9 years of surveillances for malaria morbidity and TF in Daraweesh village in eastern Sudan (1991-2004), 136 donors (15-78 years) from 43 households, treated for 278 malaria episodes ...

  16. A guide to practical radiation protection in medicine. X-Ray Ordinance. Radiation Protection Ordinance. Practice-oriented hints, comments, text compilation

    International Nuclear Information System (INIS)

    Fiebich, M.; Nischelsky, J.E.; Pfeiff, H.; Westermann, K.

    2003-01-01

    This loose-leaf collection has been compiled for users who have to implement the X-ray Ordinance and the Radiation Protection Ordinance at their place of work. It presents all acts, ordinances, safety guides, regulations and recommendations of relevance in connection with the above two ordinances, as well as practical instructions and the full text of technical codes. Radiation protection officers and other persons in charge of radiation protection will find the references, information and advice needed to solve problems encountered. (orig.) [de

  17. Grid-connected photovoltaic systems. Projecting, construction, sales - hints for expert technicians. 3. new rev. ed.; Netzgekoppelte Photovoltaikanlangen. Planung, Errichtung und Verkauf fuer den Handwerksprofi

    Energy Technology Data Exchange (ETDEWEB)

    Sandner, Thomas

    2013-02-01

    Photovoltaic conversion is one of the most efficient and also one of the fastest-growing sustainable technologies. The book starts by presenting the fundamentals of photovoltaic conversion and solar radiation and then proceeds to describe the components of grid-connected PV systems. Other issues of this book consider: On-site visit and selection of a suitable generator array; The Renewable Energy Law and the development of photovoltaic conversion in Germany; Business topics such as costs and prices, marketing, quality assurance; Internal use of solar power.

  18. Hints of popular voice. Through (and in spite of Giuseppe Gioachino Belli and Agustín García Calvo

    Directory of Open Access Journals (Sweden)

    Gerardo Gimona

    2018-01-01

    Full Text Available ¿Así que es para esto para lo que servía la literatura? ¿Para negar, uno tras otro, artículos de fe y dejarnos sin creencia ni idea alguna? ¿Servía, cuando era buena y cuando en algún caso acertaba, para negarse también a sí misma? ¿Y es que debía ante todo negarse a sí misma para poder decir algo que nos sonara a verdad? Pues algo de esto parece ocurrir en los sonetos que Giuseppe Gioachino Belli escribió, como si en ellos hablara directamente el pueblo y no un literato ni un autor culto, en dialecto romanesco; y es esto, precisamente, lo que intentaremos ir ahora comprobando, atendiendo al libro Giuseppe Gioachino Belli. 47 sonetos romanescos con las versiones de Agustín García Calvo (Editorial Lucina, Zamora, 2006.

  19. Cavity mutants of Savinase. Crystal structures and differential scanning calorimetry experiments give hints of the function of the buried water molecules in subtilisins.

    Science.gov (United States)

    Pedersen, J T; Olsen, O H; Betzel, C; Eschenburg, S; Branner, S; Hastrup, S

    1994-09-23

    The subtilisin molecule possesses several internal water molecules, which may be characterised as an integral part of the protein structure. We have introduced specific mutations (T71I, T71S, T71V, T71A and T71G) at position 71 in the subtilisin variant Savinase from Bacillus lentus. This position is involved in a hydrogen bonded network with several internal water molecules, forming a water channel. The water channel and most of the other internal water molecules are positioned in the interface between two half-domains of the subtilisin molecule. The data presented here indicate that the internal water molecules are structural, and may be the result of trapping during the folding process.

  20. Hints of the Early Jehol Biota: Important Dinosaur Footprint Assemblages from the Jurassic-Cretaceous Boundary Tuchengzi Formation in Beijing, China

    Science.gov (United States)

    Xing, Lida; Zhang, Jianping; Lockley, Martin G.; McCrea, Richard T.; Klein, Hendrik; Alcalá, Luis; Buckley, Lisa G.; Burns, Michael E.; Kümmell, Susanna B.; He, Qing

    2015-01-01

    New reports of dinosaur tracksites in the Tuchengzi Formation in the newly established Yanqing Global Geopark, Beijing, China, support previous inferences that the track assemblages from this formation are saurischian-dominated. More specifically, the assemblages appear theropod-dominated, with the majority of well-preserved tracks conforming to the Grallator type (sensus lato), thus representing relatively small trackmakers. Such ichnofaunas supplement the skeletal record from this unit that lacks theropods thus far, proving a larger diversity of dinosaur faunas in that region. Sauropods are represented by medium to large sized and narrow and wide-gauge groups, respectively. The latter correspond with earlier discoveries of titanosauriform skeletons in the same unit. Previous records of ornithischian tracks cannot be positively confirmed. Purported occurrences are re-evaluated here, the trackways and imprints, except of a single possible specimen, re-assigned to theropods. Palecologically the Tuchengzi ichnofauna is characteristic of semi-arid fluvio-lacustrine inland basins with Upper Jurassic-Lower Cretaceous deposits in northern China that all show assemblages with abundant theropod and sauropod tracks and minor components of ornithopod, pterosaur and bird tracks. PMID:25901363

  1. Academics are Reading More Electronic Journal Articles in More Subjects, Using Varying Strategies to Find and Manage Them. A Review of: Ollé, C., & Borrego, Á. (2010. A qualitative study of the impact of electronic journals on scholarlyinformation behavior. Library & Information Science Research, 32(3, 221-228.

    Directory of Open Access Journals (Sweden)

    Christina E. Carter

    2010-12-01

    Full Text Available Objective – To assess how the increase in number of electronic journals available to academic scholars has changed their information-seeking or consulting behaviour, with respect to 1 the amount and diversity of sources they read; 2 strategies they use to keep up-to-date in their fields; 3 use of personalized information services; 4 determining the value and relevance of articles; and 5 personal management of scientific information. This study is a follow-up to an earlier quantitative study (Borrego, Anglada, Barrios, & Comellas, 2007 in the same setting.Design – Qualitative, using an open-ended questionnaire, followed by personal interviews of a small group of the respondents.Setting – Universities that are members of the Consortium of Academic Libraries of Catalonia (CBUC, which is made up of the eight public Catalan universities and the National Library of Catalonia, Spain.Subjects – One hundred thirty-seven scholars from the member universities of diverse ages and disciplines. Eleven of these academics were selected for personal interviews.Methods – The authors used a two-staged approach to gather comments from researchers on their use of electronic journals. First, an open-ended, self-administered questionnaire (with some pre-testing donewas sent by e-mail to some 490 academics who had provided e-mail addresses in the quantitative study; 137 were returned and analyzed. Personal interviews were then conducted with 11 scholars who had given the most detailed answers in the questionnaire. Their ages ranged from 28 to 67; each was from a different discipline, and from six of the universities.Informed consent sheets (describing the study and guaranteeing anonymity were given to the 11 interviewees. Personal interviews were conducted in the subjects’ offices by one of the authors, and lasted between 45-60 minutes. In the interview stage, the authors wanted to examine: use and assessment of the library, access to electronic information, and impact of e-resources on information behaviour. Subjects were also asked to provide three suggestions on improving access to scientific information.Main Results – The amount of reading and number of electronic journals and other sources consulted among the scholars who participated in this study has increased. Three-quarters of survey respondents consult more journals and read more articles. The scholars reported that they are grateful for the increase in electronic information and its enhanced ease of access, and are not overwhelmed by it. Their reading has become more discriminatory, though, with many reporting “skimming” much of what they read to save time. Scholars keep up-to-date in three main ways: web browsing of journal issues, library database searches, and TOC e-mail alerts. More than 90% of survey respondents reported conducting database searches. Google and Google Scholar were often mentioned ahead of specific library database names. In determining value and relevance of an article, its author and abstract are key for scholars. In addition, personal information management techniques used by scholars were all over the board. The three main methods were use of print or electronic folders, reference management software, and no system. Many of the academics felt their information management systems were “rudimentary” (p. 225.The request for suggestions and comments on the questionnaire was not answered by “most of the sample” (p. 226. Those who did respond to this request asked for more library resources. The main complaint expressed by scholars concerned the difficulty and complexity of finding journal article content using the Library website (e.g., varying databases, difficulty of interpreting what journal electronic and print holdings are available. Because of this, a number of scholars used Google to find library-subscribed content.Conclusion – By having greater and easier access to e-journals, scholars accessing the CBUC read more articles from more disciplines. Scholars would prefer a simpler library interface to search for online content. Due to the complexity of finding article content, they use web search tools like Google and Google Scholar to get to what they need faster. The authors of this study believe research should be conducted on the use of the Consortium’s metasearch tool to reduce the complexity. Research should also be conducted on value-added features of search interfaces for particular disciplines.

  2. "Rambo" ründab Eestit äkki tulevikus / Aivar Aotäht

    Index Scriptorium Estoniae

    Aotäht, Aivar, 1970-

    2005-01-01

    Miks ei ole Ameerika märulitriloogiat "Rambo" näidanud ükski eesti telekanal ? Kommenteerivad Kanal 2 programmidirektor Olle Mirme, TV 3 programmidirektor Jüri Pihel ja ETV pressiesindaja Toomas Luhats

  3. Sisearhitektuuri uudised / Aino Ingrid Sepp

    Index Scriptorium Estoniae

    Sepp, Aino Ingrid

    2006-01-01

    Keraamiliste plaatide müügisalongi "Interno" uue sisekujunduse autorid Eerik Olle ja Ahti Petersoo. Viking Windowsi peakontori (Jüri Okas) uue sisekujunduse ja "Sämmi grilli" (Toomas Rein) uue sisekujunduse autor Taevo Gans

  4. Eesti langeb korruptsiooni tabelis / Sirje Rank

    Index Scriptorium Estoniae

    Rank, Sirje, 1966-

    2003-01-01

    Eesti on uurimisfirma Transparency International koostatud korruptsiooni tajumise indeksi tabelis 133 riigi seas 33. kohal, olles võrreldes eelmise aastaga langenud neli kohta. Tabel: korruptsiooni tajumise indeks 2003. aastal erinevates riikides

  5. Aasta jagu filme linastus pealinnas ühe matsuga / Katrin Nielsen

    Index Scriptorium Estoniae

    Nielsen, Katrin

    2001-01-01

    Pimedate Ööde Filmifestivali huvitavamaid filme : Jan Hrebejk'i "Lahus olles me kaotame" (Tšehhi Vabariik 2000), Oliver Hirschbiegeli "Eksperiment" (Saksamaa 2001) ja Bille Augusti "Laul Martinile" (Rootsi - Taani 2001)

  6. Gaboni riigipea lahkub presidendipaleest vaid jalad ees / Allan Espenberg

    Index Scriptorium Estoniae

    Espenberg, Allan

    2005-01-01

    Kesk-Aafrika riigi Gaboni president Omar Bongo püüab detsembris toimuvatel presidendivalimistel taotleda enda tagasivalimist. Bongo on juhtinud Gaboni 38 aastat, olles sellega Aafrika riigipeade hulgas kõige staazhikam valitseja

  7. Nägemine piltide kaudu : Fotograafia antropoloogiast / Jay Ruby

    Index Scriptorium Estoniae

    Ruby, Jay, 1935-

    2010-01-01

    Fotograafia ja sotsiaalteaduste suhtest visuaalse etnograafia seisukohalt. Uurimisprojektist, mille sihiks on mõista kõikide fotograafia liikide kultuurilist rolli ja funktsioone inimeste elus antropoloogilisest vaatenurgast, olles huvitatud kultuurilisest ja kommunikatiivsest, mitte hinnangulisest algest

  8. Isamaaline tundmus : Eesti ja Soome kirjamees Jüri Tilk ehk Yrjö Virula / Anu Pallas

    Index Scriptorium Estoniae

    Pallas, Anu, 1960-

    2010-01-01

    Avaliku elu tegelasest, ajakirjanikust ja karskuskirjanduse rajajast Jüri Tilgast, kes 19. sajandi lõpul töötas aktiivselt üldtuntud rahvajuhtide kõrval, olles ka Ado Grenzsteini lähim aatekaaslane

  9. "Surmaeelsed kogemused" võivad olla vaid uni / Alo Lõhmus

    Index Scriptorium Estoniae

    Lõhmus, Alo

    2006-01-01

    Surmasuust tagasi pöördunud inimeste kogetud valgusaistingud ja kehast lahkumise illusioonid võivad olle põhjustatud unelaadsest seisundist. Lexingtoni Kentucky ülikooli neuropsühholoogi Kevin Nelsoni uuringutest

  10. Simulatsioon, situatsioon, kaos / Rain Tolk

    Index Scriptorium Estoniae

    Tolk, Rain, 1977-

    2004-01-01

    Provokatiivse teleprogrammi "Ekskursioon" (Kanal 2) võrdlus ameerika ja inglise analoogidega - "Da Ali G Show" ja "The Awful Truth & TV-Nation". Lisatud Kanal 2 programmijuhi Olle Mirme kommentaar ja "Provokatiivseid saateid ja momente eesti teleajaloos" lk. 126

  11. Reflections on the fight agnaist the image of shamanism / Art Leete

    Index Scriptorium Estoniae

    Leete, Art, 1969

    2013-01-01

    Arvustus: Sundström, Olle. Kampen mot "schamanismen" : Sovjetisk religionspolitik gentemot inhemska religioner i Sibirien och norra Ryssland. Studier av inter-religiösa relationer 40. Uppsala: Universitetstryckeriet 2007

  12. Rõnok polutshil signal / Kairi Teesalu

    Index Scriptorium Estoniae

    Teesalu, Kairi

    2008-01-01

    Eluasemeturul on müügipakkumiste arv hakanud sujuvalt langema, olles kahanenud sõltuvalt linnast kuni paarikümne protsendi võrra. Diagramm: Tartu ja Tallinna korteriturg. Kommenteerivad Tõnu Toompark ja Maia Daljajev

  13. Ameerika närvilised geeniused / Karlo Funk

    Index Scriptorium Estoniae

    Funk, Karlo, 1971-

    2000-01-01

    IV Pimedate Ööde Filmifestivali filmidest : "Olles John Malkovich" ("Being John Malkovich") : režissöör Spike Jonze ja dokumentaalfilm "Ameerika film" ("American Movie") : režissöör Chris Smith

  14. Fulltext PDF

    Indian Academy of Sciences (India)

    W ith R olle's theorem as a starting point,w e dis- cuss som e geom etric and other aspects ofthe dis- .... at the equilibrium positions in a certain ¯eld of force. T his ¯eld is one due to a particle placed at each .... B y the hypothesis that R olle's property holds for f , there are at least r ¡ 3 zeroes of f 0 w hich are outside ¢ and are ...

  15. VLSI Research

    Science.gov (United States)

    1984-04-01

    Interpretation of IMMEDIATE fields of instructions (except ldhi ): W (c) (d) (e) sssssssssssss s imml9 sssssssssssssssssss...s imml3 Destination REGISTER of a LDHI instruction: imml9 0000000000000 Data in REGISTERS when operated upon: 32-bit quantity...Oll x l OOOO OOOl calli sll OOlO getpsw sra xxzOOll getlpc srl OlOO putpsw ldhi OlOl and zzzOllO or ldxw stxw Olll xor

  16. Clinicopathologic Correlation of Oral Lichen Planus and Oral Lichenoid Lesions: A Preliminary Study

    Science.gov (United States)

    Mravak-Stipetić, Marinka; Lončar-Brzak, Božana; Bakale-Hodak, Iva; Seiwerth, Sven; Majstorović, Martina; Grce, Magdalena

    2014-01-01

    Oral lichen planus (OLP) and oral lichenoid lesions (OLL) are clinically and histologically similar lesions but their treatment planning and prognosis are different. The review of the literature indicates numerous criteria to distinguish these two lesions; however there is a lot of inconsistency. Thus, the aim of this study was to determine the correlation of histopathology and clinical OLP and OLL diagnosis and to clarify which histopathologic criteria could best distinguish these two diagnoses. A retrospective study showed that clinically diagnosed 92 OLPs and 14 OLLs have been confirmed histopathologically in 52.2% and 42.9% of cases, respectively. In addition, histopathology showed statistically significant more eosinophils (P < 0.0005), plasma cells (P < 0.0005), and granulocytes (P < 0.05) in OLL than OLP. To establish histopathological diagnosis of OLP and OLL it should be mandatory to define the type of cells in mononuclear infiltrate, which can be associated more accurately with clinical feature and patient history. Therefore, currently accepted diagnostic criteria for OLP and OLL should be modified and validated on a larger number of patients taking into account particular distinguishing histopathological features. PMID:25531004

  17. Outspoken Klenski pushes political limits / Ksenia Repson

    Index Scriptorium Estoniae

    Repson, Ksenia

    2005-01-01

    Keskerakonnast välja heidetud Dimitri Klenski soovis kohalikel valimistel osaleda enda loodud valimisliiduga, kuid valimisliitu ei saanud registreerida, kuna selle nimi, "Spissok Klenskogo", oli vastuolus keeleseadusega

  18. Plaadid / Jüri F. Lotman

    Index Scriptorium Estoniae

    Lotman, Jüri F.

    2004-01-01

    Uutest heliplaatidest Dimitri from Paris "Cruising Attitude", Tim Hecker "Mirages", Ludacris "The Red Light District", Mario Frangoulis "Follow Your Heart", Loits "Vere kutse kohustab", "Flamenco Chill Sessions"

  19. Mastimännid ja muu mets : mitmekülgsuse võlu Eesti proosast aastal 2007 / Sirje Olesk

    Index Scriptorium Estoniae

    Olesk, Sirje, 1954-

    2008-01-01

    Ülevaade 2007. aasta eesti proosast. Käsitletakse järgimisi autoreid ja nende teoseid: Ene Mihkelson "Katkuhaud", Andrus Kivirähk "Mees, kes teadis ussisõnu", Jaan Kaplinski "Seesama jõgi", Tõnu Õnnepalu "Flandria päevik", Toomas Vint "Mäluauguga naine", Indrek Hargla "French ja Koulu Tarbatus", Kalle Käsper "Buridanid IV", Jaan Tooming "Teekond mäe südamesse", Ustav Mikelsaar "Tunnimehed", Henn Mikelsaar "Teema variatsioonidega", Reet Kudu "Pidupäevad võõrsil", Mara Maret Aronovich "Tagasikäiguga edasi", Aimée Beekman "Proovielu", Valentine Nõlvak "Ellujääja : mälestused", Mehis Heinsaar "Rändaja õnn", Maimu Berg "Unustatud inimesed", Mats Traat "Sarviku armastus : valik kultuuriloolisi novelle", Mihkel Mutt "Siseemigrant : novellid Rui taevalike kommentaaridega", Paavo Kivine "Kaks kavaleri", Kärt Hellerma "Ma armastasin David Copperfieldi", Piret Bristol "Paralleelmeri", Imre Siil "Mereröövlite loss", Kalju Saaber "Issanda loomaaed. Viru sektor", Veiko Märka "Lendas üle marmortahvli", Vahur Afanasjev "Kaadrid otsustavad, ehk, Sööbik ja Pisik seiklevad jälle, ehk, Eesti rahva lühike, kuid õnnelik ajalugu, Ehk kirjalik komejant tühjusest", Aarne Ruuben "Lugusid Anveltist ja Kingissepast", Epp Annus "Sina, Matilda", Peeter Helme "Puudutus", Ivar Sild "Tantsiv linn", Tui Hirv "Tähe tänav. Per musica ad astra", Tiina Laanem "Väikesed vanamehed", Angela Hofberg (pseud.) "Päev nagu elu", Marion Andra "Vähemalt...", Olle Lauli "Niguliste õpilased", Aarne Biin "Linna valitsemine", Erik Tohvri "Mürgiliblikas", Riina Kangur "Elisa", Kerttu Rakke "Küpsiseparadiis", Epp Petrone ja Dagmar Reintam "Õun ära süüa?", Elme Väljaste "Päriselu Proletariaadi puiesteel", Ketlin Priilinn "Hõbeingel", Ira Lember "Kohvik pärnade all", Paul Pajos "Krimijutud edasijõudnuile", Andres Anvelt "Punane elavhõbe", Klaara ja Kaarel Kivi "Mõrvasügis", Tiit Sepa "Hommik ühele", Lembit Uustulnd "Ruutuemanda sündroom : rahvusvaheline

  20. Upanişadların Temel Kavramları, Getirdiği Yeni Yaklaşımlar ve Hint Dinî ve Felsefî Dünyasına Katkıları

    Directory of Open Access Journals (Sweden)

    Ali İsra Güngör

    2015-11-01

    Full Text Available Hindu holy literature is composed of several texts. Vedic literature is divided by tradition into two categories: Shruti that is heard (revelation and Smriti that is remembered (not revelation. The Upanishads are part of the Shruti. They have special place and importance in this rich literature. Because, Upanishads are remarkable with respect to the content and contains new religious and philosophic thoughts. In this respect, theological bases of the concepts such as karmareincarnation and Moksha which are the keystones of Hinduism take place firstly in Upanishad texts. On the other hand, some thoughts presented by Upanishads have deeply affected Hindu culture and philosophy. Thus effects of Upanishad texts on Hindu religious beliefs, culture and philosophy are still prevailing today

  1. Ma armtub säda ŷdugt, kus mytk līb pūtumi : ehk Ma armastan seda õhtut, kus mõttest saab puudutus / Mati Hint

    Index Scriptorium Estoniae

    Hint, Mati, 1937-

    2014-01-01

    Arvustus: Ķempi Kārl. Toini sina = Teine sina / tõlge eesti keelde ja järelsõna: Karl Pajusalu. Tallinn : Eesti Keele Sihtasutus, 2013 ; Ķempi Kārl. Salats joug kolm aģa = Salatsi jõe kolm kallast = Salacas upes trīs krasti / tõlge eesti keelde: Karl Pajusalu, tõlge läti keelde: Valts Ernštreits. Tartu : Liivi Sõprade Selts, 2013

  2. Symptomatic oral lesions may be associated with contact allergy to substances in oral hygiene products

    DEFF Research Database (Denmark)

    Larsen, Kristine Røn; Johansen, J D; Reibel, J

    2017-01-01

    OBJECTIVE: Dental materials and oral hygiene products may be responsible for oral contact allergic reactions. We aimed to determine the occurrence of allergies in patients with symptomatic oral lichen planus (OLP), oral lichenoid lesions (OLLs) and stomatitis and investigate if patch testing could...... identify contact allergies to dental materials and oral hygiene products in these patients. METHODS: Forty-nine patients (7 men, 42 women) aged 31 to 77 years (61 ± 10.3 years) with symptomatic OLP, OLL or stomatitis and 29 healthy age- and gender-matched control subjects were included. They underwent.......01). Avoidance cleared symptoms in all cases. CONCLUSION/CLINICAL RELEVANCE: Allergic reactions to aroma substances in oral hygiene products are common in patients with symptomatic OLP, OLL and stomatitis....

  3. Oral lichen planus to oral lichenoid lesions: Evolution or revolution

    Science.gov (United States)

    Dudhia, Bhavin B; Dudhia, Sonal B; Patel, Purv S; Jani, Yesha V

    2015-01-01

    The diagnosis between different diseases may be impaired by clinical and histopathologic similarities, as observed in the oral lichen planus (OLP) and oral lichenoid lesion (OLL). Inspite of similar clinicopathological features; etiology, diagnosis and prognosis differ which mandates separation of OLL from OLP. Hence, it is essential for the oral physician and oral pathologist to be familiarized with the individual variations among clinicopathological features of OLP and OLL as well as to obtain a thorough history and perform a complete mucocutaneous examination in addition to specific diagnostic testing. The difficulties faced to establish the diagnosis between these two pathologies are widely investigated in the literature with a lack of definite conclusion. This review is an attempt to throw some light on these clinicopathologic entities with the aim to resolve the diagnostic dilemma. PMID:26980966

  4. Kaks kaptenit / Krister Kivi

    Index Scriptorium Estoniae

    Kivi, Krister, 1975-

    2007-01-01

    Väliseestlased Mart ja Peter Hint on teinud silmapaistvat karjääri Ameerika Lennunduses. Mart Hint töötab Boening 767 kaptenina lennukompaniis Delta, Peter Hint töötab lennukompaniis American Airlines

  5. Methodology for the Model-based Small Area Estimates of Cancer-Related Knowledge - Small Area Estimates

    Science.gov (United States)

    The HINTS is designed to produce reliable estimates at the national and regional levels. GIS maps using HINTS data have been used to provide a visual representation of possible geographic relationships in HINTS cancer-related variables.

  6. Is oral cancer incidence among patients with oral lichen planus/oral lichenoid lesions underestimated?

    Science.gov (United States)

    Gonzalez-Moles, M A; Gil-Montoya, J A; Ruiz-Avila, I; Bravo, M

    2017-02-01

    Oral lichen planus (OLP) and oral lichenoid lesions (OLL) are considered potentially malignant disorders with a cancer incidence of around 1% of cases, although this estimation is controversial. The aim of this study was to analyze the cancer incidence in a case series of patients with OLP and OLL and to explore clinicopathological aspects that may cause underestimation of the cancer incidence in these diseases. A retrospective study was conducted of 102 patients diagnosed with OLP (n = 21, 20.58%) or OLL (n = 81) between January 2006 and January 2016. Patients were informed of the risk of malignization and followed up annually. The number of sessions programmed for each patient was compared with the number actually attended. Follow-up was classified as complete (100% attendance), good (75-99%), moderate (25-74%), or poor (<25% attendance) compliance. Cancer was developed by four patients (3.9%), three males and one male. One of these developed three carcinomas, which were diagnosed at the follow-up visit (two in lower gingiva, one in floor of mouth); one had OLL and the other three had OLP. The carcinoma developed in mucosal areas with no OLP or OLL involvement in three of these patients, while OLP and cancer were diagnosed simultaneously in the fourth. Of the six carcinomas diagnosed, five (83.3%) were T1 and one (16.7%) T2. None were N+, and all patients remain alive and disease-free. The cancer incidence in OLP and OLL appears to be underestimated due to the strict exclusion criteria usually imposed. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  7. Structural Design of a 6-DoF Hip Exoskeleton using Linear Series Elastic Actuators

    OpenAIRE

    Li, Xiao

    2017-01-01

    A novel hip exoskeleton with six degrees of freedom (DoF) was developed, and multiple prototypes of this product were created in this thesis. The device was an upper level of the 12-DoF lower-body exoskeleton project, which was known as the Orthotic Lower-body Locomotion Exoskeleton (OLL-E). The hip exoskeleton had three motions per leg, which were roll, yaw, and pitch. Currently, the sufferers of hemiplegia and paraplegia can be addressed by using a wheelchair or operating an exoskeleton wi...

  8. New initiative benefits Greek students

    CERN Multimedia

    Patrice Loïez

    2003-01-01

    In 2003 the CERN summer students from the National Technical University of Athens (NTUA) included four sponsored through the newly established CERN-NTUA educational agreement, as well as two who participated under the standard CERN summer student scheme. Here Magda Lola of the CERN Recruitment Service (third from left), Evangelos Gazis of NTUA (centre) and Claude Détraz, director for fixed target and future programmes at CERN (fourth from right), pose with all six students, from left to right, Dimitris Skipis, Dimitris Kouzis-Loukas, Ilias Holis, Dimitris Perrakis, Iro Koletsos and Nassia Assiki

  9. Elmut Paavel : Soomlased tulnuks Eestisse niikuinii / Elmut Paavel ; interv. Rein Raudvere

    Index Scriptorium Estoniae

    Paavel, Elmut, 1954-

    2004-01-01

    AS-i Valga Lihatööstus tegevjuht põhjendab kolmveerandi aktsiate müümist Soome suurimale lihatööstusettevõttele Atria Group Plc. Kommenteerivad: Otepää lihatööstuse Edgar juht Maie Niit ja Eesti Lihaliidu juhatuse esimees Olle Horm

  10. Estonia beyond the edge / Eric Kluitenberg

    Index Scriptorium Estoniae

    Kluitenberg, Eric

    2004-01-01

    Festivali "Interstanding" üks initsiaatoreid arutleb 1990. aastate meedia festivalidel käsitletud teemade tähendusest eesti kultuurile ja selle identiteedile. 1999. aastal toimunud kolmanda festivali teemaks oli "Ülalpool piire - põgenemine marginaalsuse eest". Eestist saanud uute poliitilis-majanduslike ja globaalkultuuriliste võrgustike osa, olles olnud omamoodi vahetsooniks

  11. Pärnu uue kunsti muuseumis on näitus "Kümme aastat moodsat kunsti Pärnus varakapitalistliku Eesti tingimustes"

    Index Scriptorium Estoniae

    2003-01-01

    Osalevad Peeter Allik, Mila Balti, Chintis, Margit Joonas, Toomas Kuusing, Hannes Paldrok, Meeland Sepp, Inge Ting, Taje Tross, Andrus Joonas, Bille Tuul, Mariliis Beilmann, Olle Meyer, Sorge, rühmitus Non Grata, Asta Isak, Marianne Männi, Ville-Karel Viirelaid

  12. Pjotr Sedin maadleb raskustega / Kaisa Tahlfeld

    Index Scriptorium Estoniae

    Tahlfeld, Kaisa

    2008-01-01

    Pjotr Sedini firma OÜ Grove Invest seitse Tallinna kesklinna kinnistut arestiti ja pannakse 420 miljoniga enampakkumisele. Vt. samas: Sundmüüki läheb seitse krunti; Grove Investi osalusega ettevõtetel on võlad kaelas. Kommenteerib Olle Orm. Küsimustele vastab vandeadvokaat Terje Eipre. Diagramm: Majandustulemused

  13. A humidity sensitive two-dimensional tunable amorphous photonic structure in the outer layer of bivalve ligament from Sunset Siliqua

    International Nuclear Information System (INIS)

    Zhang, Weigang; Zhang, Gangsheng

    2015-01-01

    A humidity sensitive two-dimensional tunable amorphous photonic structure (2D TAPS) in the outer layer of bivalve ligament from Sunset Siliqua (OLLS) was reported in this paper. The structural color and microstructure of OLLS were investigated by reflection spectra and scanning electron microscopy, respectively. The results indicate that the reflection peak wavelength of the wet OLLS blue-shifts from 454 nm to 392 nm with the increasing of air drying time from 0 to 40 min, while the reflectivity decreases gradually and vanishes at last, relevant color changes from blue to black background color. The structural color in the OLLS is produced by a two-dimensional amorphous photonic structure consisting of aligned protein fibers, in which the diameter of protein fiber and the inter-fiber spacing are 101 ± 12 nm. Water can reversibly tune the reflection peak wavelength and reflectivity of this photonic structure, and the regulation achieved through dynamically tuning the interaction between inter-fiber spacing and average refractive index. - Highlights: • A humidity sensitive two-dimensional tunable amorphous photonic structure • Water can reversibly tune the reflection peak wavelength and reflectivity of this photonic structure. • This photonic structure may yield very useful template for artificial structures

  14. A humidity sensitive two-dimensional tunable amorphous photonic structure in the outer layer of bivalve ligament from Sunset Siliqua

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Weigang, E-mail: abczwg15@163.com [College of Materials and Chemical Engineering, Chuzhou University, Chuzhou 239000 (China); Zhang, Gangsheng [College of Material Science and Technology, Guangxi University, Nanning 530004 (China)

    2015-07-01

    A humidity sensitive two-dimensional tunable amorphous photonic structure (2D TAPS) in the outer layer of bivalve ligament from Sunset Siliqua (OLLS) was reported in this paper. The structural color and microstructure of OLLS were investigated by reflection spectra and scanning electron microscopy, respectively. The results indicate that the reflection peak wavelength of the wet OLLS blue-shifts from 454 nm to 392 nm with the increasing of air drying time from 0 to 40 min, while the reflectivity decreases gradually and vanishes at last, relevant color changes from blue to black background color. The structural color in the OLLS is produced by a two-dimensional amorphous photonic structure consisting of aligned protein fibers, in which the diameter of protein fiber and the inter-fiber spacing are 101 ± 12 nm. Water can reversibly tune the reflection peak wavelength and reflectivity of this photonic structure, and the regulation achieved through dynamically tuning the interaction between inter-fiber spacing and average refractive index. - Highlights: • A humidity sensitive two-dimensional tunable amorphous photonic structure • Water can reversibly tune the reflection peak wavelength and reflectivity of this photonic structure. • This photonic structure may yield very useful template for artificial structures.

  15. Kloonimiskuningas osutus tüssajaks / Arko Olesk

    Index Scriptorium Estoniae

    Olesk, Arko, 1981-

    2006-01-01

    Lõuna-Korea teadlane Hwang Woo-Suk astus möödunud aasta lõpus pettuses süüdistatuna tagasi Souli ülikooli professori kohalt, olles varem alusetult väitnud, et on saavutanud läbimurde geenitehnoloogias ning suudab tõhusalt tüvirakke luua

  16. Ülihiidtäht Betelgeuse kaotab massi / Jüri Ivask

    Index Scriptorium Estoniae

    Ivask, Jüri, 1961-

    2009-01-01

    Betelgeuse, heleduselt teine täht Orioni tähtkujus, on punane ülihiid - üks suurimaid tähti, mida teatakse. Olles vaid mõne miljoni aasta vanune, läheneb Betelgeuse juba oma eluea lõpule ning peab peagi plahvatama supernoovana

  17. Serum cytokine profile and clinicopathological findings in oral lichen planus, oral lichenoid lesions and stomatitis

    DEFF Research Database (Denmark)

    Larsen, Kristine Røn; Johansen, Jeanne Duus; Reibel, Jesper

    2017-01-01

    The objective of this study was to examine if clinical and histopathological variables in patients with oral lichen planus (OLP), oral lichenoid lesions (OLL), and generalized stomatitis display different cytokine profiles and if concomitant contact allergy influences this profile. Forty-nine pat......The objective of this study was to examine if clinical and histopathological variables in patients with oral lichen planus (OLP), oral lichenoid lesions (OLL), and generalized stomatitis display different cytokine profiles and if concomitant contact allergy influences this profile. Forty...... analyzed and compared between groups. Nineteen patients had OLP, primarily with ulcerative lesions on the buccal mucosa, 19 patients had OLL, and 11 patients had generalized stomatitis. All patients had oral symptoms, mainly stinging and burning. Nineteen patients and 10 healthy subjects had contact...... higher levels of IL-6 than the healthy subjects. Interferon-γ, IL-12p40, and IL-12p70 were below detection limit. Our findings indicate that OLP, OLL, and generalized stomatitis cannot be discriminated by means of the selected serum cytokines, and that the presence of concomitant contact allergy does...

  18. Filaggrin gene mutations and the distribution of filaggrin in oral mucosa of patients with oral lichen planus and healthy controls

    DEFF Research Database (Denmark)

    Larsen, K R; Johansen, J D; Reibel, J

    2017-01-01

    candidiasis. Immunohistochemistry were performed using poly- and monoclonal filaggrin antibodies. RESULTS: The immunoreactivity for filaggrin was significantly more intense in the oral mucosa in the patients with OLP/OLL compared to healthy controls (p=0.000025). No difference was noted in the incidence...

  19. Загадочное исчезновение акций / Артур Тооман

    Index Scriptorium Estoniae

    Тооман, Артур, 1971-

    2009-01-01

    Zircon Technologies AS-i ostu jaoks Gate Capital OÜ loonud isikud väidavad, et üks ettevõtte loojatest - Aleksandr Kuzin, olles ainus juhatuse liige mõlemas ettevõttes, kandis 51% aktsiatest oma ettevõttele Pidev OÜ ja kandib ettevõtte vara oma firmadele

  20. Permian Triassic palynofloral transition in Chintalapudi area ...

    Indian Academy of Sciences (India)

    Palynoassemblage-IV (Group II) is characterized by high percentage of taeniate disaccates chiefly. Lunatisporites spp. .... to the age assignment and identification of dis- ..... us pollenites. Platy saccus. Sch eurin gip olle nites. Ib is porites. In ap ertu ro pollen ites ..... graphic classification based on microfloras, macrofloras,.

  1. Iisraeli sõdurid murdsid jõuga Palestiina vanglasse / Erkki Bahovski

    Index Scriptorium Estoniae

    Bahovski, Erkki, 1970-

    2006-01-01

    Palestiina võimude teatel tungisid Iisraeli sõdurid 14. märtsil Jeeriko vanglasse, olles tapnud ühe vangivalvuri ja ühe kinnipeetu ning nõudsid Iisraeli turismiministri Rehavam Zeevi tapmises süüdistatava Palestiina Vabastamise Rahvarinde (PFLP) juhi Ahmed Saadati väljaandmist. Lisa: Kriis

  2. Monopol suretab kohaliku loomakasvataja / Oleg Gross ; interv . Illar Mõttus

    Index Scriptorium Estoniae

    Gross, Oleg, 1952-

    2005-01-01

    Väike-Maarja jäätmetehase monopoolse seisundi vastu sõna võtnud OG Elektra omanik Oleg Gross on kindel, et jäätmetehasega suretatakse kohalikud väiksemad lihatootjad välja. Kommenteerivad talupidaja Jüri Järvet ja Rakvere Lihakombinaadi direktor Olle Horm

  3. Aeg hakata Delli aktsiale mõtlema / Tõnis Oja

    Index Scriptorium Estoniae

    Oja, Tõnis, 1957-

    2008-01-01

    Delli asutaja Michael Dell on uuesti tegevjuhi kohal olles asunud ettevõtte päästmiseks kulusid kärpima ja tegema ümberkorraldusi, vahetades välja mitmed tippjuhid. Diagrammid: Aktsia hind; Majandusnäitajad

  4. Vera Poska-Grünthal - Eesti riigimehe tütar ja naisõiguslane / Kairi Ilison

    Index Scriptorium Estoniae

    Ilison, Kairi

    2010-01-01

    Riigivanema ja poliitiku Jaan Poska tütrest Vera Poska-Grünthalist (1898-1986), kes oli tuntud ajakirjanik ja naisõiguslane. Põgenes Teise maailmasõja ajal Rootsi ja asutas seal 1952. aastal ajakirja "Triinu", mis lõpetas ilmumise Torontos 1995. aastal, olles Eesti naiste ühendaja vabas maailmas

  5. Kujundusideid / Ketlin Priilinn

    Index Scriptorium Estoniae

    Priilinn, Ketlin, 1982-

    2006-01-01

    Eesti sisearhitektide Annes Arro, Jorma Holmi, Kaire Kemp-Tishleri (kamina sepised Heigo Jelle), Andro Kööbi, Rein Lauri (seintel Anne Parmasto ja Rein Kelpmanni maalid), Taso Mähari (eramu arhitekt Emil Urbel, seinal Lemming Nageli maal "Punane joon all - Burn Out"), Eerik Olle, Meelis Pressi ja Anu Vainomäe kujundatud elutoad. 33 värv. ill

  6. Estonian living in safest of times / Ella Karapetyan

    Index Scriptorium Estoniae

    Karapetyan, Ella

    2010-01-01

    Peaminister Andrus Ansip ütles kevadisi riigikaitsekursuseid avades, et tema hinnangul elab Eesti julgeoleku seisukohalt oma ajaloo ilmselt kõige turvalisemat etappi, olles NATO ja Euroopa Liidu liige. Kursuste avamistseremooniast võtsid osa ka kaitseminister Jaak Aaviksoo, välisminister Urmas Paet, siseminister Marko Pomerants ja kaitseväe juhataja kindralleitnant Ants Laaneots

  7. Vtorostepennõje ljudi na ekrane "Tjomnõh notshei" / Boris Tuch

    Index Scriptorium Estoniae

    Tuch, Boris, 1946-

    2001-01-01

    Pimedate Ööde Filmifestivali filme n.ö. "väikestest inimestest" : Kira Muratova "Väikesed inimesed" (Ukraina 2001), Artur Aristakisjani "Koht maa peal" (Venemaa 2001) ja Jan Hrebejk'i "Lahus olles me kaotame" (Tšehhi Vabariik 2000)

  8. Umer Ritshard Farnsvort

    Index Scriptorium Estoniae

    2000-01-01

    Suri iseenda käe läbi ameerika näitleja Richard Farnsworth, kes sel aastal 80-aastasena sai Oscari osa eest David Lynchi filmis "Straight Story", olles vanim kõikidest, kes kunagi parima meesnäitleja Oscari saanud

  9. Põud : [luuletused] / Enn Tuuling

    Index Scriptorium Estoniae

    Tuuling, Enn

    2002-01-01

    Sisu: Põud ; Aian ; Inne pikset ; Süküsõdang tarõn ; Üü tulek ; Rebäse külä vana sann ; Vana maja ; "Kes oll̀ tuu miis, kes sinno ehit ..." ; Pööningul ; Talv 1960/61. Eluloolisi andmeid autori kohta lk. 358-359

  10. Märtsis selgub Eesti parim tööandja / Raigo Neudorf, Agne Narusk

    Index Scriptorium Estoniae

    Neudorf, Raigo

    2004-01-01

    Konsultatsioonifirma Fontes korraldas koostöös rahvusvahelise ettevõttega Hewitt Associates uuringu, mille põhjal selgub Eesti parim tööandja. Küsimusele uuringus osalemise põhjuse kohta vastavad AS-i EMT personalijuht Milvi Tepp ja AS-i Tallinna Küte personaliosakonna juhataja Ene Olle

  11. Hans Jürman 85 : Hans Jürman: kes ma olen? / Hans Jürman

    Index Scriptorium Estoniae

    Jürman, Hans, 1923-2014

    2010-01-01

    Hans Jürmani lapsepõlvest, kooliaastatest ning ülikooliajast. Olles hariduselt eesti filoloog on Hans Jürman töötanud ka apteekrina ja õpetajana, kuid suurema osa oma elust raamatukogudes, põhiliselt Tallinna Keskraamatukogus ja Eesti NSV Riiklikus Avalikus Raamatukogus, viimasel ajal tegeleb terminoloogiaga

  12. Pärnus tähistatakse moodsa kunsti 10. aastapäeva

    Index Scriptorium Estoniae

    2003-01-01

    Ülevaatenäitus Pärnu Uue Kunsti Muuseumis. Näitusel osalevad Peeter Mudist, Mila Balti, Chintis, Margit Joonas, Toomas Kuusing, Hannes Paldrok, Meeland Sepp, Inge Ting, Taje Tross, Andrus Joonas, Bille Tuul, Marliis Beilmann, Olle Meyes, Sorge, Non Grata, Asta Isak, Marianne Männi

  13. Estonian social dialogue in the context of European employment strategy / Raul Eamets, Epp Kallaste

    Index Scriptorium Estoniae

    Eamets, Raul, 1964-

    2003-01-01

    Sotsiaalne partnerlus on Euroopa Tööhõivestrateegia läbivaks tööpoliitika kujundamise meetmeks, olles olulise tähtsusega nii rahvusliku kui kohaliku tasandi tööhõive meetmete kujundamisel. Eestis on sotsiaalne partnerlus nõrgalt arenenud

  14. Evaluation of patients with oral lichenoid lesions by dental patch testing and results of removal of the dental restoration material

    Directory of Open Access Journals (Sweden)

    Emine Buket Şahin

    2016-12-01

    Full Text Available Background and Design: Oral lichenoid lesions (OLL are contact stomatitis characterized by white reticular or erosive patches, plaque-like lesions that are clinically and histopathologically indistinguishable from oral lichen planus (OLP. Amalgam dental fillings and dental restoration materials are among the etiologic agents. In the present study, it was aimed to evaluate the standard and dental series patch tests in patients with OLL in comparison to a control group and evaluate our results. Materials and Methods: Thirty-three patients with OLL or OLP and 30 healthy control subjects, who had at least one dental restoration material and/or dental filling, were included in the study. Both groups received standard series and dental patch test and the results were evaluated simultaneously. Results: The most frequent allergens in the dental series patch test in the patient group were palladium chloride (n=4; 12.12% and benzoyl peroxide (n=2, 6.06%. Of the 33 patients with OLL; 8 had positive reaction to allergents in the standard patch test series and 8 had positive reaction in the dental patch test series. There was no significant difference in the rate of patch test reaction to the dental and standard series between the groups. Ten patients were advised to have the dental restoration material removed according to the results of the patch tests. The lesions improved in three patients [removal of all amalgam dental fillings (n=1, replacement of all amalgam dental fillings with an alternative filling material (n=1 and replacement of the dental prosthesis (n=1] following the removal or replacement of the dental restoration material. Conclusion: Dental patch test should be performed in patients with OLL and dental restoration material. Dental filling and/or prosthesis should be removed/replaced if there is a reaction against a dental restoration material-related allergen.

  15. Kokkade olümpiat oodates / Krista Dudarenko

    Index Scriptorium Estoniae

    Dudarenko, Krista, 1970-

    2008-01-01

    Restoranide Gloria ja Egoist peakokk Dimitri Demjanov koordineerib Eesti esmakordset osavõttu mainekast kokandusvõistlusest Bocuse d'Or, mille kohalik eelvoor toimub 16. märtsil Swissotel Tallinnas

  16. Õigeksmõistev otsus vallandas publiku tormilise aplausi / Tiiu Põld ; kommenteerinud David Vseviov ; Marju Lauristin

    Index Scriptorium Estoniae

    Põld, Tiiu, 1945-

    2009-01-01

    Harju maakohtu õigeksmõistvast otsusest aprillirahutuste korraldamises süüdistatavate Dmitri Linteri, Maksim Reva, Dimitri Klenski ja Mark Sirõki kohta. Kommenteerivad David Vseviov ja Marju Lauristin

  17. Fine 5 kolib Kumu lavale

    Index Scriptorium Estoniae

    2006-01-01

    Kumu kunstimuuseumi auditooriumis toimub 21. veebruaril Fine 5 kaasaegse tantsu etendus "Panus". Esinevad Tiina Ollesk, Irina Pähn, žonglöör Dimitri Kruus, disainer Rain Saukas ja muusik Mattias Siitan

  18. Eesti kivimid aitasid lahendada iidse jääaja mõistatust / Tiit Kändler

    Index Scriptorium Estoniae

    Kändler, Tiit, 1948-

    2010-01-01

    Ajakirjas Palaeogeography, Palaeoclimatology, Palaeoecology ilmunud artiklist, milles lahatakse jääaja tekkimise põhjusi. Autorite seas on ka USA Indiana ülikooli teadlane Seth Young ja Dimitri Kaljo TTÜ geoloogia instituudist

  19. Afanasjev porugalsja s Pindre na sobranii Sojuza rossiiskihh grazhdan / Roman Vikulov

    Index Scriptorium Estoniae

    Vikulov, Roman

    2005-01-01

    Vene kodanike liidu korraldatud valimiseelsest koosolekust, kus toetati Vene Erakonna Eestis kandidaate Gennadi Afanasjevit ja Jelena Ziolkovskat ning millest võttis osa ka Tallinna linnavalitsuse saadik Dimitri Klenski

  20. Centrist speaks out for bilingualism / Ksenia Repson

    Index Scriptorium Estoniae

    Repson, Ksenia

    2005-01-01

    Tallinna linnavolikogu liige Dimitri Klenski soovib, et volikogu istungitel võetaks kasutusele ka vene keel. Volikogu liikme Igor Sedashevi arvates püüab Klenski endale enne kohalikke valimisi tähelepanu tõmmata

  1. Vaprad lucky loser'id / Jüri Aarma ; kommenteerinud Tanja Muravskaja

    Index Scriptorium Estoniae

    Aarma, Jüri, 1951-

    2009-01-01

    Tanja Muravskaja isikunäitus "Lucky Losers" Tallinna Linnagaleriis. Eksponeeritud videoportreed vene rahvusest Eesti kodanikest Dimitri Klenskist, Adolf Käisist, Anna Levandist, Tatjana Muravjovast, Mihhail Stalnuhhinist, Eduard Tomanist ja Boris Tuchist

  2. The happy Bulgarian family

    CERN Multimedia

    2000-01-01

    From left to right, last row to first row: Ilka Antcheva, Georgi Antchev, Dimitri Borilkov, Ivana Hristova, Petiu Petev, Peicho Petkov, Borislav Pavlov, Peter Hristov, Mihail Tchijov, Stefan Piperov, Ekaterina Ivanova, Dimitar Kolev, Roumen Tzenov.

  3. GLORIOUS DISCOURSES AND COMPLETE IGNORANCE: STUDENT PERCEPTION ON CANTEMIR’S WORK

    Directory of Open Access Journals (Sweden)

    Maria CERNAT

    2014-05-01

    Full Text Available Although the works of Dimitrie Cantemir and his son Antiloh are consideed among the most important in the fields of history and litterature, nowadays it is hard to find a research initiative or a research program specialized in the study of Dimitrie Cantemir’s work. It is the indisputable merit of a Romanian born historian like Stefan Lemny to offer a very complex and profound account on the life and work of Dimitrie and Antioh Cantemir. But, like other remarkable efforts, this is an individual research. It is my intention to focus on the recent works regarding the life and work of Dimitrie Cantemir in order to prove that beside the moments of celebration there is little or no interest in the work of this remarkable Romanian intellectual. I parallel this situation with the information students have on Dimitrie Cantemir. In the first section of my article I shall focus on how much information on Cantemir do our students rely have. Thus I shall make an empirical research questioning the students of the first year on the most common facts about Cantemir’s work and life. In the second section of my article, I shall try to answer questions like how many volumes having as main subject matter the works of Cantemir have been published recently. In what branches of science the works of Cantemir have been mostly analyzed? What is the ratio between the works concerning his personality and those concerning specific topics in specific works of Dimitrie Cantemir.

  4. Atomic-Scale Imaging of Surfaces and Interfaces. Materials Research Society Symposium Proceedings Held in Boston, Massachusetts on November 30-December 2, 1992. Volume 295

    Science.gov (United States)

    1992-01-01

    ofrindi idual siruxtural ui.inix cn. hoes er, be atitntcdiru Aith current comnputer hardwa~e A firsit oi Xr Model for the detect structure max be...02115 ABSTRACT Atomic force microscopy (AFM) has been used to image the surface atomic structure of hydroxyapatite lCaI0(PO4 )6 (Oll)2 1, HA. and...The structure and chemical nature of the minerals hydroxyapatite and brushite have been studied extensively in biological researchf-t0 HA is found

  5. Leben mit Estland : Paul-Gerhard von Hoerschelmann zum 80. Geburtstag / Heinrich Wittram

    Index Scriptorium Estoniae

    Wittram, Heinrich

    2012-01-01

    Olles Põhja-Elbe Jutlustajate Seminari direktor alustas Paul-Gerhard von Hoerschelmann koostööd Eesti Evangeelse Luterliku Kirikuga 1988. aastal. Nõmmel sündinud pastori pojana olid tal selle koostöö arendamiseks igati head eeldused. 1997. aastal sai Paul-Gerhard Hoerschelmannist EELK Usuteaduse Instituudi rektor. Aastatel 1996-1998 teenis ta väikesearvulist saksakeelset kogudust Tallinnas. Aastast 2006 EELK' aupraost

  6. Strength and Microstructure of Ceramics

    Science.gov (United States)

    1989-11-01

    Forex - one particular alumina ceramic, I our own detailed crack ample, the relatively large values of r, and c* for the VI observations, and those of...particularly toughness indices, 1i71", indicating that there is sonic the c° , T parameters. However, the indentation mcth- kind of trade -o1Tbetwecn...macroscopic and microsnpic odology takes us closer to the strengths of specimens toughness levels, and that this trade -off is cont’olled by with natural

  7. Conference on Occupational Health Aspects of Advanced Composite Technology in the Aerospace Industry Held in Dayton, Ohio on 6-9 February 1989. Volume 2. Proceedings

    Science.gov (United States)

    1989-03-01

    intrinsic psycho- social stressors (long work hours, cahcer- phobia , misinformation from health care providers, labor-management friction, media hype) with...critical materials led the way for many of the military, industrial and social changes of the past. Historians have named periods after materials, such as...ORGANIC 10 STEEL AND TITANIUM COMPOSITES oL-L I 1960 1970 1980 199 200 01 YEAR -- rv 21 Figure 4 Structural material distributions - ,ibsoniu diid

  8. re ipit tion re onstru tion using ringEwidth hronology of rim lyn ed r ...

    Indian Academy of Sciences (India)

    r nges from IHHEEIUS mF hue to he vy r inf ll it does not grow in the e stern rim l y eyond q rhw lF he ringEwidth hronology of rim l y n ed r @eh. IIUIEEIWVVAD prep red from tree ores olle ted from two disjun t m ture forests in western rim l y . @figure IAD h s een used in the present studyF het ils of the methodology ...

  9. Army Helicopter Crashworthiness

    Science.gov (United States)

    1983-10-01

    telescoping characteris- S . I N tics when struck from above by the crewm~an in a hard landing/ cr’ish. The design is to be ItIst 3SQ 30 1 to is 20 28...aurVivable 015 Am-ny rotary-winq accident* froms January 1972 to beembuar 1942. Vioure 16 shows the rOll frequency of ocCurrence4 whon only impacto of *25

  10. Uus Saksamaa lubab väikeriigid oma hõlma alla võtta / Jeroen Bult

    Index Scriptorium Estoniae

    Bult, Jeroen

    2005-01-01

    Nii väikeriigid kui ka maailma suurriigid on huvitatud sellest, milliseks kujuneb Saksamaa välispoliitika Angela Merkeli võimul olles: esimese kolme ametis oldud nädala jooksul võib järeldada, et Angela Merkel ei jätka Gerhard Schröderi sirgjoonelist välispoliitilist kurssi, vaid eelistab balansseerida erinevate suurvõimude vahel, unustamata samas ka väikeriike. Lisa: Angela Merkel

  11. A Topological Model for Parallel Algorithm Design

    Science.gov (United States)

    1991-09-01

    effort should be directed to planning, requirements analysis, specification and design, with 20% invested into the actual coding, and then the final 40...be olle more language to learn. And by investing the effort into improving the utility of ai, existing language instead of creating a new one, this...193) it abandons the notion of a process as a fundemental concept of parallel program design and that it facilitates program derivation by rigorously

  12. Ehitusmeistrist arhitektiks - G. F. W. Geist Tartu linnaruumi kujundajana 19. sajandi esimesel poolel / Epi Tohvri

    Index Scriptorium Estoniae

    Tohvri, Epi

    2004-01-01

    Ehitusmeistri ja arhitektina töötanud Georg Friedrich Wilhelm Geisti tegevusest Tartus 1810-1846, mil ta etendas olulist rolli Tartu linnaruumi väljaehitamisel, olles pea kõikide linna ja kroonu tellitud avalike hoonete (kaubahoov, hobupostijaam, kreiskool, vaestemaja, haigla jne.) ning kirikute plaanide koostaja ja ehitustööde juhataja, arhitektuuriõpetaja ja lõpuks ka arhitekt

  13. The investigation formation of complexes of Fe(III) and Fe(II) in the water solution of imidazole at 298 K

    International Nuclear Information System (INIS)

    Radjabov, U.R.; Yusupov, Z.N.; Sharipov, I.Kh.

    2001-01-01

    C H lm=0.1 mol/l, C F e(II)=1·10 - 4 m ol/l and iron sterns: 0.10, 0.25, 0.50 and 1.00 mol/l. It is established that in the investigated systems form at different on composition mono-, polynuclear, homo-- and heterovalent coordination compounds. In aids of the oxidation function accurate the composition, defined the constants formation and domination sphere of complex forms

  14. Planeering kui kaasaegne teos par excellence : kas tulevikku saab välja mõelda? = The plan as a contenporary work par excellence : can the future be made up? / Toomas Tammis

    Index Scriptorium Estoniae

    Tammis, Toomas, 1969-

    2011-01-01

    Tulevikku saab kavandada läbi visioonide, läbi erinevate erialade teadmistest kokku lõimunud loomingulise akti, mis ei saa kunagi olla liiga täpne. Planeering saab olla teatav süsteem, mis suudab lõputult produtseerida väikseid üsna täpselt koha- ja keskkonnatundlikke produkte, jäädes ise pidevasse loomisse ning pooleliolekusse, olles pidevas interaktsioonis ühiskonnaga viimast lõputult monitoorides ja muutes

  15. Väike luulekaleidoskoop. III / Jürgen Rooste

    Index Scriptorium Estoniae

    Rooste, Jürgen, 1979-

    2009-01-01

    Ülevaade järgmistest luuleraamatutest: Anmann, Aarne. Südametunnistuse mälestuseks. Tartu : A. Anmann, 2009 ; Ilmet, Peep. Meilmail. Tallinn : Varrak, 2009 ; Kasemaa, Andrus. Lagunemine. Tallinn : Eesti Keele Sihtasutus, 2009 ; Kuus, Anti ; Oll, Sulev. Öö mõte on kuus. Tallinn : Akta A. K., 2008 ; Meres, Triinu. Lagunemine. Tartu : Hermes, 2009 ; Tasuja, Triin. Provintsiluule. Tartu : Värske Rõhk, 2009

  16. Structure sismique du socle paléozoïque du bassin des Doukkala, Môle côtier, Maroc occidental. Indication en faveur de l'existence d'une phase éo-varisqueSeismic structure of the Doukkala basin, Palaeozoic basement, western Morocco: a hint for an Eovariscan fold-and-thrust belt

    Science.gov (United States)

    Echarfaoui, Hassan; Hafid, Mohamed; Salem, Abdallah Aı̈t

    2002-01-01

    Seismic profiles and well data from the Doukkala basin unravel the structure of the Palaeozoic basement and suggest that this coastal zone of western Morocco was affected by a compressive phase during the Frasnian. This resulted in the formation of upright, plurikilometric folds associated with reverse faults (North Doukkala), and of asymmetrical folds associated with mostly west verging ramps (South Doukkala). Folding involved all pre-Upper Frasnian formations and caused partial or total hiatus of Upper Frasnian-Strunian strata. This event can be correlated with the orogenic phase reported from more internal domains of the Morocco Hercynian belt, where it is referred to as the 'Bretonne' or 'Eovariscan' phase. To cite this article: H. Echarfaoui et al., C. R. Geoscience 334 (2002) 13-20

  17. Claves para la comprensión de las relaciones entre la lengua, la cultura y la sociedad yuhup: una perspectiva etnolingÜística* Hints towards the comprehension of the relationship between the yuhup language, culture and society: an ethnolinguistic perspective

    Directory of Open Access Journals (Sweden)

    Ana María Ospina Bozzi

    2008-12-01

    Full Text Available Este artículo ofrece una mirada etnolingüística sobre algunos aspectos del pueblo yuhup, mediante un análisis que relaciona la lengua, la sociedad y la cultura. A manera de contextualización se presenta un resumen de la indagación realizada, se describe el entorno cultural y lingüístico de los pueblos nómades del noroeste amazónico y se evalúa el estado de la investigación sobre ellos. Se abordan aspectos sociales y culturales del pueblo yuhup, ilustrando -con datos lingüísticos- su historia reciente, su ocupación del territorio, y su categorización de plantas, animales y nociones espaciales.This paper presents an ethnolinguistic overview of the yuhup community by analyzing the way language, society, and culture are related. A contextualization of this relationship is outlined by means of a summary of the research carried out, a description of the cultural and linguistic environment of nomad communities in the Northeast Amazon, and an evaluation of research on these communities. Social and cultural aspects of the yuhup community are dealt with taking into account linguistic data, their recent history, their occupied territory, and their categorization of plants, animals, and spatial notions.

  18. Response of the Rumen Microbiota of Sika Deer (Cervus nippon Fed Different Concentrations of Tannin Rich Plants.

    Directory of Open Access Journals (Sweden)

    Zhipeng Li

    Full Text Available High throughput sequencing was used to examine the rumen microbiota of sika deer fed high (OLH and low concentration (OLL of tannin rich oak leaves. The results showed that Prevotella spp. were the most dominant bacteria. The most predominant methanogens were the members of the order Methanoplasmatales. The dominant rumen protozoa were Entodinium longinucleatum, Eudiplodinium maggii, and Epidinium caudatum, and the fungal communities were mostly represented by Piromyces spp. Moreover, the relative abundance of Pseudobutyrivibrio spp. (P=0.026, unidentified bacteria (P=0.028, and Prevotella spp. (P=0.022 was lower in the OLH group than in the OLL group. The concentration of propionate in the OLH group was greater than in the OLL group (P=0.006. Patterns of relationships showed that methanogens belonging to the order Methanoplasmatales were negatively correlated with Treponema spp., Ent. Longinucleatum, and acetate. Methanosphaera stadtmanae was positively correlated to propionate, while Methanobrevibacter ruminantium was negatively associated with Methanobrevibacter thaueri and Methanobrevibacter millerae. Tannins altered the rumen microbes and fermentation patterns. However, the response of the entire rumen microbiota and the relationship between rumen microorganisms and the fermentation parameters were not fully understood.

  19. Serum cytokine profile and clinicopathological findings in oral lichen planus, oral lichenoid lesions and stomatitis

    Science.gov (United States)

    Johansen, Jeanne Duus; Reibel, Jesper; Zachariae, Claus; Pedersen, Anne Marie Lynge

    2017-01-01

    Abstract The objective of this study was to examine if clinical and histopathological variables in patients with oral lichen planus (OLP), oral lichenoid lesions (OLL), and generalized stomatitis display different cytokine profiles and if concomitant contact allergy influences this profile. Forty‐nine patients and 29 healthy age‐ and gender‐matched subjects were included. Demographic and clinical data immunohistochemical findings in mucosal specimens, results of contact allergy testing, and serum levels of tumor necrosis factor‐α, interferon‐γ, interleukin (IL)‐6, IL‐10, IL‐12p40, and IL‐12p70 were analyzed and compared between groups. Nineteen patients had OLP, primarily with ulcerative lesions on the buccal mucosa, 19 patients had OLL, and 11 patients had generalized stomatitis. All patients had oral symptoms, mainly stinging and burning. Nineteen patients and 10 healthy subjects had contact allergies, primarily to fragrance ingredients. Patient groups did not differ with regard to oral symptoms, clinical pattern of the lesions, or contact allergy. Serum cytokine levels did not differ between the different patient groups and were not related to histopathological findings. The patients had higher levels of IL‐6 than the healthy subjects. Interferon‐γ, IL‐12p40, and IL‐12p70 were below detection limit. Our findings indicate that OLP, OLL, and generalized stomatitis cannot be discriminated by means of the selected serum cytokines, and that the presence of concomitant contact allergy does not influence the cytokine expression. PMID:29744205

  20. Collaboration and peer tutoring in chemistry laboratory education

    NARCIS (Netherlands)

    Ding, N.; Harskamp, E.G.

    2011-01-01

    The aim of this study is to examine the effectiveness of collaborative learning with hints and peer tutoring with hints, and individual learning with hints in chemistry laboratory education in a secondary school. A total of 96 eleventh graders participated in this study. The study has a randomized

  1. evaluation of total annual costs of heat exchanger networks using

    African Journals Online (AJOL)

    This study presents pinch analysis of some heat exchanger networks (HENs) problems using Hint integration (HINT) software. Three examples reported to have been solved using different approaches by various researchers to obtain the least possible total annual cost (TAC) were solved using the Hint software. In this work ...

  2. NNS computing facility manual P-17 Neutron and Nuclear Science

    International Nuclear Information System (INIS)

    Hoeberling, M.; Nelson, R.O.

    1993-11-01

    This document describes basic policies and provides information and examples on using the computing resources provided by P-17, the Neutron and Nuclear Science (NNS) group. Information on user accounts, getting help, network access, electronic mail, disk drives, tape drives, printers, batch processing software, XSYS hints, PC networking hints, and Mac networking hints is given

  3. Mendeleiev, el que pudo haber sido y no fue

    OpenAIRE

    Bascuñán Blaset, Aníbal

    2008-01-01

    The life of Dimitri Ivanovich Mendeleiev is revisited in this paper. After studying based on the support of his mother, he managed to receive a fellowship to make work with the best European chemists of that time: Bunsen, Dumas, Kirchhoff, Liebig, Würtz and Erlenmeyer. Dimitri attended the Karlsruhe Conference in 1860, fact that he afterwards revealed as key to the proposal of his Periodic Table in 1869, when he was as young as 35 years old, and he proposed a whole set of predictions about un...

  4. Putin ei kiirusta enam MRP pakti hukka mõistma / Tuuli Koch

    Index Scriptorium Estoniae

    Koch, Tuuli

    2005-01-01

    President Arnold Rüütli pressiesindaja Eero Raun ja Venemaa presidendi pressiesindaja Dimitri Peskov kajastavad Vladimir Putini seisukohti Molotovi-Ribbentropi pakti ümberhindamise kohta erinevalt. Vt. samas: Rüütel sõitis Moskvast Kiievisse. Töövisiit Moskvasse 20.-22.01.2005. Töövisiit Ukrainasse 22.-24.01.2005

  5. (Wild)Fly far and away: the evolution of the JBoss Application Server

    CERN Multimedia

    CERN. Geneva

    2015-01-01

    About the speaker Dimitris is the Engineering Manager of the WildFly / JBoss Enterprise Application Server team at Red Hat, based out of Neuchâtel. He served as the JBoss AS project lead for several years and he has been a JBoss addict and contributor f...

  6. Preparation for Lithuania's leadership over the EU / Rokas M. Tracevskis

    Index Scriptorium Estoniae

    Tracevskis, Rokas M.

    2010-01-01

    14. jaanuaril toimunud Leedu välisministri Vygaudas Ušackase ja Kreeka asevälisministri Dimitris Droutsase kohtumisel räägiti ka sellest, et 2013. aasta teisel poolel saab Leedust Euroopa Liidu eesestujamaa. Kreeka saab Euroopa Liidu eesistujamaaks 2014. aasta esimesel pool

  7. Либеральное образование предлагает выбор / Лилия Крысина

    Index Scriptorium Estoniae

    Крысина, Лилия

    2011-01-01

    Tallinna Ülikooli Katariina kolledžis õpitakse ameerika liberaalse hariduse mudeli järgi - Liberal Arts education, mis võimaldab laialdaselt õppeaineid valida. Selgitusi jagavad Katariina Kolledži direktor Dimitri Mironov ja kolledži kolmanda kursuse tudeng Nadežda Šilova

  8. Ştefania Cristescu-Golopenţia and the Developing Understanding of the Magical Universe of Romanian Villages

    Directory of Open Access Journals (Sweden)

    ION CUCEU

    2013-07-01

    Full Text Available This article represents the first part of a study concerning the research on magic carried out by Ştefania Cristescu-Golopenţia in the context of the monographic campaigns of Dimitrie Gusti's School (1929-1945. The second part examines Sanda Golopenţia's 1984-2011 "reconstruction" of her mother's work.

  9. Südame poolest sinimustvalge / Kristel Kossar

    Index Scriptorium Estoniae

    Kossar, Kristel

    2012-01-01

    Edukatest ja andekatest noortest venelastest Eestis - jalgpallur Konstantin Vassiljev, internetiäri looja ja poliitik Andrei Korobeinik, helilooja Tatjana Kozlova, Tallinna Ülikooli Katariina kolledži direktor Dimitri Mironov, sõjaajaloolane, õpetaja ja Tallinna Ülikooli doktorant Igor Kopõtin. Nende arvamused Eestist ja venelaste osalusest Eesti ühiskonnaelus

  10. 9. mail Moskvasse minna ei tohi / Heiki Suurkask

    Index Scriptorium Estoniae

    Suurkask, Heiki, 1972-

    2004-01-01

    Autori arvates tähendaks Eesti Vabariigi presidendi visiit 9. mail Moskvasse sõjaroimarite õigeksmõistmist. Lisa: Kas Eesti president peaks minema 9. mail Moskvasse? Küsimusele vastavad: Heiki Ahonen, Dimitri Klenski, Karmo Tüür

  11. Modelli tabamas / Andri Ksenofontov

    Index Scriptorium Estoniae

    Ksenofontov, Andri, 1962-

    2009-01-01

    Tallinna Linnagaleriis 3. maini avatud Tanja Muravskaja isikunäitus "Lucky Losers" ("Õnnelikud kaotajad") esitab seitsme vene rahvusest Eestis tuntud inimese videoportreed. Portreteeritavad on Dimitri Klenski, Adolf Käis, Anna Levandi, Tatjana Muravjova, Mihhail Stalnuhhin, Eduard Toman ja Boris Tuch

  12. Case report

    African Journals Online (AJOL)

    ebutamanya

    2015-09-18

    Sep 18, 2015 ... Dimitris Koufakis1, Dimitrios Konstantopoulos1, Theocharis Koufakis2,&. 1Larissa Macula Center, Larissa, Greece, 2Department of Internal Medicine, General Hospital of Larissa, Larissa, Greece. &Corresponding author: Theocharis Koufakis, Department of Internal Medicine, General Hospital of Larissa, ...

  13. Low Power Implementation of Non Power-of-Two FFTs on Coarse-Grain Reconfigurable Architectures

    NARCIS (Netherlands)

    Zhang, Q.; Wolkotte, P.T.; Smit, Gerardus Johannes Maria; Rivaton, Arnaud; Quevremont, Jérôme

    2005-01-01

    The DRM standard for digital radio broadcast in the AM band requires integrated devices for radio receivers at very low power. A System on Chip (SoC) call DiMITRI was developed based on a dual ARM9 RISC core architecture. Analyses showed that most computation power is used in the Coded Orthogonal

  14. El papel de los sistemas de relevo de fosfatos en la respuesta al estrés y la diferenciación celular en Aspergillus nidulans /

    OpenAIRE

    Vargas Pérez, Itzel Aidé sustentante.

    2009-01-01

     tesis que para obtener el grado de Doctor en Ciencias Bioquímicas, presenta Itzel Aidé Vargas Pérez ; asesor Dimitris Georgellis. VIII, 66 páginas : ilustraciones. Doctorado en Ciencias Bioquímicas UNAM, Instituto de Fisiología Celular, 2009

  15. INTRODUCCIÓN A LA METODOLOGÍA DE LA INVESTIGACIÓN EN BIOÉTICA: SUGERENCIAS PARA EL DESARROLLO DE UN PROTOCOLO DE INVESTIGACIÓN CUALITATIVA INTERDISCIPLINARIA INTRODUÇÃO À METODOLOGIA DA PESQUISA EM BIOÉTICA: SUGESTÕES PARA O DESENVOLVIMENTO DE UM PROTOCOLO DE PESQUISA QUALITATIVA INTRODUCTION TO INVESTIGATION’S METHODOLOGY IN BIOETHICS: HINTS FOR THE DEVELOPMENT OF AN INTERDISCLINARY QUALITATIVE PROTOCOL

    Directory of Open Access Journals (Sweden)

    María de la Luz Casas Martínez

    2008-01-01

    Full Text Available El avance de la bioética requiere de la ciencia para su desarrollo. La investigación en bioética parte de la interdisciplinariedad, lo cual complica su realización. Uno de los puntos conflictivos para aquellos que se inician en la investigación es la constitución de un adecuado protocolo. En este trabajo se pretende exponer un panorama general sobre los pasos de la integración de un protocolo con base en la investigación cualitativa.O desenvolvimento da ciência provoca o avanço da bioética. A pesquisa em bioética parte da interdisciplinaridade, a qual complica sua realização. Um dos pontos conflitivos para iniciantes na pesquisa é a constituição de um protocolo adequado. Este trabalho pretende expor um panorama geral sobre os passos da integração de um protocolo com base na pesquisa qualitativa.Bioethics’ advance requires science’s support for its development. Bioethics’ investigation stems from interdisciplinarity which, of course, complicates its fulfilment. One of the items in conflict for beginners in the investigation field is the establishment of a protocol. This work pretends to state a general overview about the steps that have to be taken to integrate a protocol based on qualitative investigation.

  16. Masking Release for Igbo and English

    OpenAIRE

    Ebem, Deborah U.; Desloge, Joseph G.; Reed, Charlotte M.; Braida, Louis D.; Uguru, Joy O.

    2013-01-01

    In this research, we explored the effect of noise interruption rate on speech intelligibility. Specifically, we used the Hearing In Noise Test (HINT) procedure with the original HINT stimuli (English) and Igbo stimuli to assess speech reception ability in interrupted noise. For a given noise level, the HINT test provides an estimate of the signal-to-noise ratio (SNR) required for 50%-correct speech intelligibility. The SNR for 50%-correct intelligibility changes depending upon the interruptio...

  17. Esimene foto Tallinnast? / Tõnis Liibek

    Index Scriptorium Estoniae

    Liibek, Tõnis

    2007-01-01

    Kõigi eelduste kohaselt võiks vanim Tallinna kujutav foto pärineda ajavahemikust 1845-55. Suure tõenäosusega võib vanim Tallinna foto asuda Saksamaal, olles ümberasujate poolt kaasa võetud. Teadaolevalt vanim Tallinna fotojäädvustus pärineb 1850. aastate lõpust, reservatsioonidega võiks see olla Tallinna Linnamuuseumis säilitatav ülesvõte Toompeale viivast äsja valminud Falgi teest. Tallinnas tegutsenud esimestest fotograafidest.

  18. Identification and Quantification of the Water Soluble Components of JP-4 and a Determination of Their Biological Effects upon Selected Freshwater Organisms.

    Science.gov (United States)

    1981-11-30

    minutes. Absorbances ere read at 630am on a Perkin-Elmer (Coleman 124) double beam speztrophotonater and compared to a standard curve made from para ... aminophenol (PAP), 0.05mg to 0-00oll Q- "lagM.Lnat RfteklpMi4I &&all UndWE 0.5m1 of aninopyrine stock solution (7.0mg/mI buffer) was added to the...on the HPLC column mill be collected and counted in a liq- uid scintillation counter G. Scanning electron microscopy will be used for studying gross

  19. Mida õpetab Georgia sõda / Martin Helme

    Index Scriptorium Estoniae

    Helme, Martin, 1976-

    2008-01-01

    Ilmunud ka: Pärnu Postimees 16. aug. lk. 19. Autori hinnangul tuleks Gruusia konfliktist tehtavatest järeldustest tingituna tugevdada olulisel määral Eesti kaitseväge ja relvastust, Venemaa ründe all olles aga loobuda Lääne nõudest vaherahu nimel tagasi tõmbuda. Samuti tuleks arvestada ka asjaoluga, et kohalik venekeelne kogukond on riigile sisepoliitiliselt suureks ohuks. Autori sõnul on ka Eesti esindatus välismissioonidel ressursside raiskamine ning oma vägede koju toomine tugevdaks riigi kaitsevõimet

  20. Eesti proosa 2007 - kultuuri ja tsivilisatsiooni vahel / Peeter Helme

    Index Scriptorium Estoniae

    Helme, Peeter, 1978-

    2008-01-01

    Ülevaade 2007. aasta eesti proosast. Käsitletakse järgimisi autoreid ja nende teoseid: Ene Mihkelson "Katkuhaud", Jaan Kaplinski "Seesama jõgi", Toomas Vint "Mäluauguga naine", Mehis Heinsaar "Rändaja õnn", Maimu Berg "Unustatud inimesed", Mihkel Mutt "Siseemigrant", Vahur Afanasjev "Kaadrid otsustavad", Epp Annus "Sina, Matilda", Ivar Sild "Tantsiv linn", Tiina Laanem "Väikesed vanamehed", Olle Lauli "Niguliste õpilased", Aarne Biin "Linna valitsemine", Jaan Aps ja Joonas Sildre "Hinglõõm". Ka Armin Kõomäe loomingust. Artikli aluseks on Eesti Kirjanduse Seltsi 2007. a. eesti kirjanduse ülevaatekoosolekul peetud ettekanne

  1. snerti lEhissip tion flux me surements over south f y of feng l during ...

    Indian Academy of Sciences (India)

    his p per des ri es me surement of irEse p r meters nd estim tion of sensi le nd l tent he t fluxes y the snerti lEhissip tion99 te hnique over south f y of feng lF he d t were olle ted on. y g r u ny during fyfwi E ilot ruise during the period PQrd y to er IWWV to IPth xovem er. IWWV over south f y of feng lF he fluxes re estim ...

  2. Evaluación de hidrogeles para aplicaciones agroforestales

    OpenAIRE

    Barón Cortés, Andrés; Barrera Ramírez, Ingrid Xiomara; Boada Eslava, Luis Francisco; Rodríguez Niño, Gerardo

    2010-01-01

    Con hidrogeles sintetizados por medio de la técnica de polimerización en suspensión inversa (PSI), compuestos por acrilamida y acrilato de potasio entrecruzados con N, N’ metilen-bis-acrilamida y que presentan diferentes comportamientos desde el punto de vista de capacidad y velocidad de hinchamiento, módulo elástico y propie-dades de liberación, se estudia la modificación de las propiedades hidráulicas de un suelo tipo franco arcilloso realizando curvas de retención de humedad, empleando oll...

  3. xumeri l simul tion of the m rine ound ry l yer hr teristi s over the fy of ...

    Indian Academy of Sciences (India)

    se surf e temper ture nd surf e rel tive humidity th t re olle ted on o rd y g r u ny F he tive onve tion se @from QIst y to er EE. Pnd xovem erA here fter referred s g seEI nd the suppressed onve tion se @Qrd EE Sth xovem erA referred s g seEPF por g seEID the model initi l ondiE tions re prep red using the verti l profiles ...

  4. Essays on Industry Portfolios and Macroeconomic News

    OpenAIRE

    Järvinen, Jari

    2000-01-01

    Viime vuosina tiedotusvälineissä on aktiivisesti tulkittu osakemarkkinoiden päivittäisiä liikkeitä erilaisten uutisten perusteella. Usein uutisoidaan esimerkiksi, että "osakekurssit laskivat odotettua parempien työllisyyslukujen vuoksi" tai, että "inflaation kiihtyminen nosti korkoja ja laski pörssikursseja." Erilaisten taloustilastojen julkistamispäivät ovatkin tärkeitä ajankohtia sijoittajille, sillä mikäli ne poikkeavat markkinoiden keskimääräisistä odotuksista, tulisi näillä uutisilla oll...

  5. Electronic Properties of Functional Biomolecules at Metal/Aqueous Solution Interfaces

    DEFF Research Database (Denmark)

    Zhang, Jingdong; Chi, Qijin; Kuznetsov, A.M.

    2002-01-01

    in electronic properties and stochastic single-molecule features and can be probed by new methods which approach the single-molecule level. Olle of these is in situ scanning tunneling microscopy (STM) in which single-molecule electronic properties directly in aqueous solution are probed. In situ STM combined...... with physical electrochemistry, single-crystal electrodes, and spectroscopic methods is now a new dimension in interfacial bioelectrochemistry. We overview first same approaches to spectroscopic single-molecule imaging, including fluorescence spectroscopy, chemical reaction dynamics, atomic force microscopy...

  6. Romanian Libray Science Distance Education. Current Context and Possible Solutions

    Directory of Open Access Journals (Sweden)

    Silvia-Adriana Tomescu

    2012-01-01

    We thought it would be very useful to propose a model of teaching, learning and assessment for distance higher librarianship tested on www.oll.ro, Open learning library platform to analyze the impact on students, and especially to test the effectiveness of teaching and assessing knowledge from distance. We set a rigorous approach that reflects the problems facing the Romanian LIS education system and emphasizes the optimal strategies that need to be implemented. The benefits of such an approach can and classified as: innovation in education, communicative facilities, and effective strategies for teaching library science.

  7. Structural Health Monitoring 2007: Quantification, Validation, and Implementation

    Science.gov (United States)

    2008-07-01

    Sflf·Dial.nosis 11:00-11:20 Roton;:raft. Lallllcll """’~ LesM.u Lea.. td ~lllSpirfd ’Id C.libralioll P~IlOStic:s S)’S1.~:IV Piptiiltt$, a.d i.SH;\\1...Strllttural Hnlill Mooitonn or Real Brld "In’ l!Iln No.·,,1 Flbf,r tit At«lel"OllWler ,.299 10.20 -10:40 M. Bruns. Th. Nllschl::e-Pa I, K 011 er, llJ Braunsch

  8. Friday Harbor Marina Expansion Study--San Juan Island, Washington: Final Detailed Project Report and Environmental Assessment.

    Science.gov (United States)

    1981-04-01

    1) nor at any other land or water site in the area. The existing wood enclosed plastic flo- tation chambered breakwater would continue to deteriorate...large bates of absorbent chips on hand to deal with minor oil spills. We have ordered from Crowley Environmental Services, Seattle, Washington 100 3M TY...Oll ’ ih ICbI of 811) , ,* (&) Power or natural #;41%4 the ibuve ifllomiiuci is true snd1. Luniple:it Is i U.6~ I. ( i.iilu hat~ ihr lca . a&icn.y mai~y

  9. Characterisation of Fibre Reinforced Titanium Matrix Composites. (La Caracterisation des Materiaux Composites a Matrice de Titane Renforces par Fibres)

    Science.gov (United States)

    1994-02-01

    consolidation des materiaux composites sont disponibles pour la fabrication de composants structuraux. A l’eure actuelle, certains pays diveloppent des...mat~itmru te si -Le6prouveite rayonimee perniet d’approcher ces caract~nstiqtues en uldisant des plaques disponibles stir 22-4 I ll/ol1N a12/ollN a22...Compe’: tesi Septernher I193. 23-2 are unlikely to behave as homogeneous components in service other factors become materials. The combination of elastic

  10. History of the Organization and Operations of the Committee of Operations Analysts

    Science.gov (United States)

    1944-01-01

    indu.atrlal tar&eta for 8- _’".’"’"_’’’,’’’ Of·. lgbt .onths, the effect would be to impair very c .... ,,’Q .. "’· the olipAoitq of the Weatern .Axis to...figure for 1944 III1.ght be achieved. The Ori6ntal EoertOll1at, ·,.tatedthllt;, ot! the haitI ! of 9S way. and of existing techniquee, • of 300,000 tou

  11. Enterprise risk management

    Energy Technology Data Exchange (ETDEWEB)

    Eaton, C. [Enbridge, Calgary, AB (Canada)

    2015-07-01

    Enterprise risk management (ERM) is a relative new, holistic and strategic approach for managing risks in modern organizations. ERM builds on and extends traditional risk management (RM). Risk is the effect of uncertainty on objectives - positive and/or negative. Risk management is a set of practices used to understand and address risk. ERM is a form of RM that emphasizes risk aggregation and integration. Risk aggregation is combining individual risks into categories ({sup r}olled up{sup )}. risk integration is embedding RM into organizational contexts ({sup b}uilt in{sup )}.

  12. Vello Vinn : Eripära eesti graafikas = A curiosity in Estonian graphic art / Jüri Hain

    Index Scriptorium Estoniae

    Hain, Jüri, 1941-

    2007-01-01

    Klaasikunsti õppinud Vello Vinn kerkis 1970-ndatel aastatel esile oma oforditehnikas peenekoeliste tööde erilisusega, luues kummastavaid kooslusi, kus eri valdkondadest pärit komponendid olid aheldatud ootamatustesse seostesse. Tol ajal kuulus ta vaieldamatult eesti graafikakunsti tippu, olles fantaasiaküllane visionäär, kelle teostes ilmnes selge sotsiaalkriitiline mõõde. Rahvusvaheliselt on tuntuks saanud ka oma eksliibriste ja raamatuillustratsioonidega, viljelnud ka kollaaži. 1990-ndaist aktiivne sürrealistliku rühmituse "Para '89" liige, osaledes edukalt mitmetel välisnäitustel

  13. Effects of Ionization-Induced Smog on Air Chemistry.

    Science.gov (United States)

    1987-01-30

    MAR 33 APR eoiton may n* wJse vi+til Ctn l en u SEC’.ITY C ,SSIC-ACN OF -’S PAGE All Ott 𔃻t OitlDOrn are OllOel.i UNCLASSIFIED %N UNCLASSIFIED SECURITY...reported around 5.85 om and 7.5 pim . However, these were not observed in our measure- ments with nitric acid deliberately added to the air sample...term buildup of absorption in the 6.7 pim to 7.4 pm range and a shorter-lived (8 minute decay) absorption near 6.2 pm, and a shorter-lived absorption

  14. Selected Works of Oded Schramm

    CERN Document Server

    Benjamini, Itai

    2011-01-01

    This volume is dedicated to the memory of the late Oded Schramm (1961-2008), distinguished statistician. Throughout his life, Oded made profound and beautiful contributions to mathematics that will have a lasting influence. In these two volumes, Editors Itai Benjamini and Olle Haggstrom have collected some of his papers, supplemented with three survey papers by Steffen Rohde, Haggstrom and Cristophe Garban that further elucidate his work. The papers within are a representative collection that shows the breadth, depth, enthusiasm and clarity of his work, with sections on Geometry, Noise Sensiti

  15. Relational Programming.

    Science.gov (United States)

    1983-09-01

    be illustrated by example. If ’z’ is the name of an individual and ’C’ is the name of a class (set), then ’ zEC ’ means that the individual denoted by ’z...will abbreviate this un z. Conversely, if C is a single element class, then un-1 C selects the unique member of that class: un-1C = Lz( zEC ). It is...Professor Peter Henderson1 Department of Computer Science SUNY at Stony Brook Long Island, NY 11794 Dr. Olle Olsson Department of Computer Science

  16. Forschungszentrum Juelich, Institut fuer Kernphysik/COSY. Annual report 2007

    Energy Technology Data Exchange (ETDEWEB)

    Buescher, M.; Hanhart, C.; Krewald, S.; Machner, H.; Maier, R.; Meissner, U.G.; Ritman, J.; Stockhorst, H.; Stroeher, H. (eds.)

    2008-03-15

    The following topics are dealt with, Physics at COSY, external experiments, theoretical investigations. COSY operation and developments, preparation for FAIR. See hints under the relevant topics. (HSI)

  17. Electronic Journals: Publishing via Internet's World Wide Web.

    Science.gov (United States)

    van Brakel, Pieter A.

    1995-01-01

    Provides hints for setting up and maintaining a multimedia scholarly journal. Details include limitations of paper and electronic journals, and requirements for publishing successful electronic journals. (JKP)

  18. Forschungszentrum Juelich, Institut fuer Kernphysik/COSY. Annual report 2007

    International Nuclear Information System (INIS)

    Buescher, M.; Hanhart, C.; Krewald, S.; Machner, H.; Maier, R.; Meissner, U.G.; Ritman, J.; Stockhorst, H.; Stroeher, H.

    2008-03-01

    The following topics are dealt with, Physics at COSY, external experiments, theoretical investigations. COSY operation and developments, preparation for FAIR. See hints under the relevant topics. (HSI)

  19. Production of carcinogenic acetaldehyde by Candida albicans from patients with potentially malignant oral mucosal disorders.

    Science.gov (United States)

    Gainza-Cirauqui, M L; Nieminen, M T; Novak Frazer, L; Aguirre-Urizar, J M; Moragues, M D; Rautemaa, R

    2013-03-01

    Production of carcinogenic acetaldehyde by Candida has been suggested to contribute to epithelial dysplasia and oral carcinogenesis. Oral lichen planus (OLP), oral lichenoid lesion (OLL) and oral leukoplakia (OL) are potentially carcinogenic oral diseases where colonisation by Candida is common, but acetaldehyde production by Candida has not been studied. Acetaldehyde production in ethanol (11 mM), glucose (100 mM), ethanol-glucose (11 mM and 100 mM) or red wine (1200 mM ethanol) incubation by Candida albicans from patients with OLL (n = 6), OLP (n = 16), OL (n = 6) and controls (n = 6) was measured by gas chromatography. Participants completed a questionnaire regarding their smoking habits and alcohol consumption. All Candida albicans isolates produced potentially carcinogenic levels of acetaldehyde (>100 μM) in all incubations containing ethanol. The control group isolates produced the highest acetaldehyde levels. Isolates from smokers produced more acetaldehyde in all incubations than those from non-smokers. The difference was significant in ethanol-glucose incubation. Isolates from patients who were both smokers and drinkers produced the highest amounts when incubated in ethanol, ethanol-glucose and wine. Candida albicans isolated from potentially carcinogenic oral diseases can produce mutagenic amounts of acetaldehyde. Cigarette smoking and alcohol consumption may favour adaptational changes resulting in the upregulation of candidal acetaldehyde metabolism. © 2012 John Wiley & Sons A/S. All rights reserved.

  20. Epidermal growth factor receptor expression in different subtypes of oral lichenoid disease.

    Science.gov (United States)

    Cortés-Ramírez, Dionisio-Alejandro; Rodríguez-Tojo, María-Jose; Coca-Meneses, Juan-Carlos; Marichalar-Mendia, Xabier; Aguirre-Urizar, José-Manuel

    2014-09-01

    The oral lichenoid disease (OLD) includes different chronic inflammatory processes such as oral lichen planus (OLP) and oral lichenoid lesions (OLL), both entities with controversial diagnosis and malignant potential. Epidermal growth factor receptor (EFGR) is an important oral carcinogenesis biomarker and overexpressed in several oral potentially malignant disorders. To analyze the EGFR expression in the OLD to find differences between OLP and OLL, and to correlate it with the main clinical and pathological features. Forty-four OLD cases were studied and classified according to their clinical (Group C1: only papular lesions / Group C2: papular and other lesions) and histopathological features (Group HT: OLP-typical / Group HC: OLP-compatible) based in previous published criteria. Standard immunohistochemical identification of EGFR protein was performed. Comparative and descriptive statistical analyses were performed. Thirty-five cases (79.5%) showed EGFR overexpression without significant differences between clinical and histopathological groups (p<0.05). Histological groups showed significant differences in the EGFR expression pattern (p=0.016). Conlusions: All OLD samples showed high EGFR expression. The type of clinical lesion was not related with EGFR expression; however, there are differences in the EGFR expression pattern between histological groups that may be related with a different biological profile and malignant risk.

  1. Assessment of the financial implications for laparoscopic liver surgery: a single-centre UK cost analysis for minor and major hepatectomy.

    Science.gov (United States)

    Abu Hilal, Mohammed; Di Fabio, Francesco; Syed, Shareef; Wiltshire, Robert; Dimovska, Eleonora; Turner, David; Primrose, John N; Pearce, Neil W

    2013-07-01

    Laparoscopic hepatectomy is progressively gaining popularity. However, it is still unclear whether the laparoscopic approach offers cost advantages compared with the open approach, especially when major hepatectomies are required. Data providing useful insights into the costs of the laparoscopic approach for clinicians and hospitals are needed. The aim of this study is to assess the financial implications of the laparoscopic approach for two standardized minor and major hepatectomies: left lateral sectionectomy and right hepatectomy. A cost comparison analysis of patients undergoing laparoscopic right hepatectomy (LRH) and laparoscopic left lateral sectionectomy (LLLS) versus the open counterparts was performed. Data considered for the comparison analysis were operative costs (theatre cost, consumables and surgeon/anaesthetic labour cost), postoperative costs (hospital stay, complication management and readmissions) and overall costs. A total of 149 patients were included: 38 patients underwent LRH and 46 open right hepatectomy (ORH); 46 patients underwent LLLS and 19 open left lateral sectionectomy (OLLS). For LRH the mean operative, postoperative and overall costs were £10,181, £4,037 and £14,218; for ORH the mean operative, postoperative and overall costs were £6,483 (p costs were £5,460, £2,599 and £8,059; for OLLS the mean operative, postoperative and overall costs were £5,841 (p = 0.874), £5,796 (p cost advantage of the laparoscopic approach for left lateral sectionectomy and the cost neutrality for right hepatectomy.

  2. Unsupervised MDP Value Selection for Automating ITS Capabilities

    Science.gov (United States)

    Stamper, John; Barnes, Tiffany

    2009-01-01

    We seek to simplify the creation of intelligent tutors by using student data acquired from standard computer aided instruction (CAI) in conjunction with educational data mining methods to automatically generate adaptive hints. In our previous work, we have automatically generated hints for logic tutoring by constructing a Markov Decision Process…

  3. Web-Based Quiz-Game-Like Formative Assessment: Development and Evaluation

    Science.gov (United States)

    Wang, Tzu-Hua

    2008-01-01

    This research aims to develop a multiple-choice Web-based quiz-game-like formative assessment system, named GAM-WATA. The unique design of "Ask-Hint Strategy" turns the Web-based formative assessment into an online quiz game. "Ask-Hint Strategy" is composed of "Prune Strategy" and "Call-in Strategy".…

  4. Intracellular pH distribution as a cell health indicator in Saccharomyces cerevisiae

    DEFF Research Database (Denmark)

    Aabo, Thomas; Glückstad, Jesper; Siegumfeldt, Henrik

    2011-01-01

    .d.(pHint)) to describe the internal pH distributions. The cellular pH distributional response to external stress such as heat has not previously been determined. In this study, the intracellular pH (pHi) and the s.d.(pHint) of Saccharomyces cerevisiae cells exposed to supralethal temperatures were measured using...

  5. Network Security Risks of Online Social Networking in the Workplace

    Science.gov (United States)

    2013-11-01

    Facebook explains pornographic shock spam, hints at browser vulnera- bility, nakedsecurity. URL – http://nakedsecurity.sophos.com/2011/11/16/ facebook...explains- pornographic -shock-spam-hints-at-browser-vul nerability/. 22 UNCLASSIFIED UNCLASSIFIED DSTO–GD–0772 44. Blatz, J. (2011) CSRF: attack and

  6. Adaptive filtering primer with Matlab

    CERN Document Server

    Poularikas, Alexander D

    2006-01-01

    INTRODUCTIONSignal ProcessingAn ExampleOutline of the TextDISCRETE-TIME SIGNAL PROCESSINGDiscrete Time SignalsTransform-Domain Representation of Discrete-Time SignalsThe Z-TransformDiscrete-Time SystemsProblemsHints-Solutions-SuggestionsRANDOM VARIABLES, SEQUENCES, AND STOCHASTIC PROCESSESRandom Signals and DistributionsAveragesStationary ProcessesSpecial Random Signals and Probability Density FunctionsWiener-Khinchin RelationsFiltering Random ProcessesSpecial Types of Random ProcessesNonparametric Spectra EstimationParametric Methods of power Spectral EstimationProblemsHints-Solutions-SuggestionsWIENER FILTERSThe Mean-Square ErrorThe FIR Wiener FilterThe Wiener SolutionWiener Filtering ExamplesProblemsHints-Solutions-SuggestionsEIGENVALUES OF RX - PROPERTIES OF THE ERROR SURFACEThe Eigenvalues of the Correlation MatrixGeometrical Properties of the Error SurfaceProblemsHints-Solutions-SuggestionsNEWTON AND STEEPEST-DESCENT METHODOne-Dimensional Gradient Search MethodSteepest-Descent AlgorithmProblemsHints-Sol...

  7. Cooperation on New Bases in the Wider Black Sea Region

    Science.gov (United States)

    2013-03-01

    Change and Continuity in National Identity, Second Edition (Maryland: Lanham, 2010), 223. 16 Ibid., 230. 17 Noam Chomsky , “Ossetia-Russia-Georgia...Current History, October 2010, 287. 29 Tsygankov, Russia’s Foreign Policy, 240. 30 Jack F. Matlock, Jr., quoted in Noam Chomsky , “Ossetia-Russia...32 Ibid., 226. 33 Chomsky , “Ossetia-Russia-Georgia.” 34 Tsygankov, Russia’s Foreign Policy, 240. 35 Dimitry Simes, “Loosing Russia: The Cost of

  8. Polarization Techniques for Mitigation of Low Grazing Angle Sea Clutter

    Science.gov (United States)

    2017-01-01

    is better in practice. Dimitris Manolakis Acknowledgments One can undertake learning a vast, deep area of knowledge by entering its dark pool slowly...reformed English lit major can only carry a metaphor so far. There are many people deserving of my deepest thanks who happen to swim mostly in other pools...challenging to detect. Solutions posed in the literature to date have been either computationally impractical or lacked robustness. This dissertation

  9. Настольная игра помогает изучать русский язык и Россию / Андрей Бабин

    Index Scriptorium Estoniae

    Бабин, Андрей

    2013-01-01

    Õppemängu CONTACT© Russian eesmärk on Moskva linnas ning vene kultuuris mugavalt orienteeruma ja vene keeles suhtlema õppimine. Tallinna Ülikooli poolt on koostatud analoogne mäng välistudengitele vene keele õppimiseks inglise keele baasil. Mängu koostasid Slaavi Keelte ja Kultuuride Instituudi lektor Inna Adamson ja Katariina Kolledži direktor Dimitri Mironov, kes jagab mängu kohta selgitusi

  10. 20 December 2011 - Georgian Minister of Education and Science Georgia D.Shashkini signing an agreement and the guest book with CERN Director- General R. Heuer; visiting CMS underground area with Technical Coordinator A. Ball;in the ATLAS underground area with Former Collaboration Spokesperson P. Jenni, and thoughout accompanied by Advisers T. Kurtyka and R. Voss

    CERN Multimedia

    VMO Team

    2011-01-01

    The minister of education and science, Dimitri Shashkini, visited CERN to sign an agreement on behalf of Georgia. The signature by the minister reflects both Georgia’s interest in expanding its co-operation with CERN and the new responsibility of the ministry of education and science for funding scientific activities. The agreement will provide enhanced participation of Georgian scientists in CERN’s projects, either directly or through Georgia’s membership in JINR.

  11. Amplifying Riboswitch Signal Output using Cellular Wiring

    Science.gov (United States)

    2017-01-30

    included in this document for any purpose other than Government procurement does not in any way obligate the U.S. Government. The fact that the...release. 88ABW-2016-3094, 23 June 2016 ACKNOWLEDGEMENTS We thank Dr. Christopher Voigt (Massachusetts Institute of Technology) for his generous gift of...plasmids, and Dr. Dimitri Deheyn (U.C. San Diego) for his generous gift of GFPa1, and Dr. Jason Micklefield (University of Manchester, UK) for

  12. Members of the ALICE collaboration greet the arrival of the experiment's first 500 lead tungstate crystals

    CERN Multimedia

    Maximilien Brice

    2002-01-01

    L. to r: Vladislav Manko (Kurchatov Institute, Moscow, PHOS project leader), Arne Klovning (University of Bergen, PHOS technical coordinator), Vyacheslav Demanov (VNIIEF, Sarov), Bjorn Pommeresche (University of Bergen), Hans de Groot (CERN, ALICE resource coordinator), Dimitri Alexandrov (Kurchatov Institute, Moscow), Mikhail Ippolitov (Kurchatov Institute, Moscow), Yuri Vinogradov (VNIIEF, Sarov), Chris Fabjan (CERN, ALICE technical coordinator), Yuri Sibiriak (Kurchatov Institute, Moscow), Sergei Sadovsky (IHEP, Protvino), Jurgen Schukraft (CERN, ALICE spokesperson).

  13. Public infrastructure investment: A bridge to productivity growth?

    OpenAIRE

    Jerome Levy Economics Institute of Bard College

    1993-01-01

    Table of Contents: Preface, by Dimitri B. Papadimitriou; Public Capital and Economic Growth, by David Alan Aschauer; New Federal Spending for Infrastructure: Should We Let This Genie Out of the Bottle?, by Douglas Holtz-Eakin. Abstract: This brief presents contrasting views on the effects of public infrastructure investment on private sector productivity. David Alan Aschauer states that the slower rate of productivity growth since the early 1970s-coupled with an aging population, the declinin...

  14. Impact of corneal cross-linking combined with photorefractive keratectomy on blurring strength

    OpenAIRE

    Labiris, Georgios; Sideroudi, Haris; Angelonias, Dimitris; Georgantzoglou, Kimonas; Kozobolis, Vassilios P

    2016-01-01

    Georgios Labiris,1,2 Haris Sideroudi,2 Dimitris Angelonias,2 Kimonas Georgantzoglou,2 Vassilios P Kozobolis1,21Department of Ophthalmology, University Hospital of Alexandroupolis, 2Eye Institute of Thrace, Alexandroupolis, GreecePurpose: The aim of this study was to evaluate the impact of corneal cross-linking combined with photorefractive keratectomy (PRK) on blurring strength.Methods: A total of 63 patients with keratoconus were recruited for this study, and two study groups were formed acc...

  15. Mobility Research for Future Vehicles: A Methodology to Create a Unified Trade-Off Environment for Advanced Aerospace Vehicle

    Science.gov (United States)

    2018-01-31

    road-mapping and analogies. Technology road-mapping consists of projecting major technological elements of product design and manufacturing together...relevant to the UH-60 Blackhawk upgrades. GE is expected to begin production of the engine in 2025. It is designed to produce 50% more power at SL...Boeing Prof. Advanced Systems Design dimitri.mavris@aserospace.gatech.edu Kyle Collins Research Faculty kyle.collins@asdl.gatech.edu Aerospace

  16. Review of photodynamic therapy in actinic keratosis and basal cell carcinoma

    Directory of Open Access Journals (Sweden)

    Marica B Ericson

    2008-03-01

    Full Text Available Marica B Ericson1,2, Ann-Marie Wennberg1, Olle Larkö11Department of Dermatology; 2Department of Physics, Göteborg University, Göteborg, SwedenAbstract: The number of non-melanoma skin cancers is increasing worldwide, and so also the demand for effective treatment modalities. Topical photodynamic therapy (PDT using aminolaevulinic acid or its methyl ester has recently become good treatment options for actinic keratosis and basal cell carcinoma; especielly when treating large areas and areas with field cancerization. The cure rates are usually good, and the cosmetic outcomes excellent. The only major side effect reported is the pain experienced by the patients during treatment. This review covers the fundamental aspects of topical PDT and its application for treatment of actinic keratosis and basal cell carcinoma. Both potentials and limitations will be reviewed, as well as some recent development within the field.Keywords: photodynamic therapy, actinic keratosis, basal cell carcinoma

  17. Short outlines of books by Estonian authors / Janika Kronberg, Rutt Hinrikus

    Index Scriptorium Estoniae

    Kronberg, Janika, 1963-

    2008-01-01

    Arvustus: Afanasjev, Vahur. Kosmos. Tallinn : Jutulind, 2008 ; Hvostov, Andrei. Võõrad lood. Tallinn : Tänapäev, 2008 ; Lauli, Olle. Niguliste õpilased. Tallinn : Verb, 2007 ; Rooste, Jürgen. Tavaline eesti idioot. Pärnu : Ji, 2008 ; Talvet, Jüri. Silmad peksavad une seinu. Tartu : Ilmamaa, 2008 ; Beekman, Aimée. Proovielu. Tallinn : Varrak, 2008 ; Kivi, Aita. Lähedal. Tallinn : Ajakirjade Kirjastus, 2008 ; Beekman, Vladimir. Alles see oli. Tallinn : Tänapäev, 2008 ; Viiding, Elo. Püha Maama. Tallinn : Tuum, 2008 ; Nõu, Helga. Peaaegu geenius ehk Schrödingeri kassi otsimas. Tallinn : Atlex, 2008 ; Unt, Lii. Parim näitleja linnas. Varanasi päevaraamat. Tallinn : Eesti Ekspressi Kirjastus, 2007 ; Sild, Ivar. Tantsiv linn. Tallinn : Tuum, 2007

  18. Analysis of Air Force Secondary Power Logistics Solution Contract

    Science.gov (United States)

    2010-05-21

    for the F-1 5 award that thc SPLS contract has 9 option years during which the contracting offi cer mUSI determine whether the price for each option...slaled III part 2. $p..",:lal ..!lOrIS muSI he la ~cn 10 m:lkc ~ure Ihal i lone~’\\\\ e ll 0.11)1.𔄀 nOI "prolif ’ ’’l th ;l t\\ tr ForN’, .:~p.:n6...Iludil r~’I,:Oll1mendfllioll thai prup;:r dtlenlli’lO’ll\\)ll for hundling mUSI ~ obl:ained. NOfl-OOIlcur 11’,lh Ic \\’el 01 dclCnlllnftltOTl rtl

  19. Hirm, raha ja armastus / Margot Visnap, Kadi Herkül, Immo Mihkelson

    Index Scriptorium Estoniae

    Visnap, Margot, 1959-

    1999-01-01

    Teleteatri aastaringist - ETV kaheksa lavastust seitsmelt lavastajalt : Toomas Hussar/Ervin Õunapuu "Linnapea ehk Hirmu põhivormid". Rezh. T. Hussar. Eetris 1. jaan. 1998; A.H. Tammsaare/Ain Prosa "Ma armastasin sakslast". Rezh. A. Prosa. Eetris 24. veebr. 1998; Dennis Potter "Sa oled koor minu kohvis". Rezh. Vilja Palm. Eetris 1. jaan. 1999; Ain Prosa/Karl Ristikivi "lihtne lugu, lõpuga". Rezh. Ain Prosa. Eetris 28. nov. 1998; Betti Alver/Margus Kasterpalu "Tuulearmuke". Rezh. Elo Selirand. Eetris 23. mail 1998; Faama Filmi ja ETV teleteatri koostöö "Isa", sts. ja rezh. Mart Kivastik. Eetris 28. märtsil 1998; "Lilled Leale", sts. ja rezh. Olle Mirme Toomas Vindi novelli põhjal; Rein Saluri "Andke neile andeks", lav. Talvo Pabut. Eetris 19. okt. 1998

  20. Acoustic properties of Indian Ocean manganese nodules in relation to physical constitution and chemical composition

    Digital Repository Service at National Institute of Oceanography (India)

    Mukhopadhyay, R; Ramana, Y.V.

    . India. 337 338 R. MurmoP~mavAv and Y. V. R.~NA 14- l~- S • 2*E :,3" r4" r • / / / / ~ot//Q IN ,# ,.. o~:; ill It? Q g S||lCeOUS ClOy (SCl CENTRAL INDIAN BASIN sx O IttS 0 loe a,tO OCEAN S Ilic i ,~o 'de ~ScJ LEGEND S~} SS... ...... ,, lee lie O L. O,?e O'll I IOO k I'11. f~ leo 0 Seal ment l"ranslllonl S T ) i i zoe O Pet eg~: clay IPCI I IsoO I t I Fig. I. Location of the samples (sediment distribution after UDIN'rSEV, 1975). were polished using fine carborundum powder...

  1. Mathematical methods for hydrodynamic limits

    CERN Document Server

    Masi, Anna

    1991-01-01

    Entropy inequalities, correlation functions, couplings between stochastic processes are powerful techniques which have been extensively used to give arigorous foundation to the theory of complex, many component systems and to its many applications in a variety of fields as physics, biology, population dynamics, economics, ... The purpose of the book is to make theseand other mathematical methods accessible to readers with a limited background in probability and physics by examining in detail a few models where the techniques emerge clearly, while extra difficulties arekept to a minimum. Lanford's method and its extension to the hierarchy of equations for the truncated correlation functions, the v-functions, are presented and applied to prove the validity of macroscopic equations forstochastic particle systems which are perturbations of the independent and of the symmetric simple exclusion processes. Entropy inequalities are discussed in the frame of the Guo-Papanicolaou-Varadhan technique and of theKipnis-Oll...

  2. Geophysical Investigation in Support of Beaver Dam Comprehensive Seepage Investigation.

    Science.gov (United States)

    1988-05-01

    29 JANUARY 1986 1118.35 3 MARCH 1986 1117.10 43 _9_ KANSAS CITY 65S city 630 FigreD.MiteNa rLA~c c roof To PMMEE OZRKS oll 4) 4 c0 x 9 c~ c 4) 154 iL...8217 q 10 S To F S T I U yI: 0 E H N IN sb a ITIU M C F T E A K E UOE S CRI P T 10N I N E T 0 s N s ~ LIYESTW *IE T I LIGHT To IAIRK i; RAYO I 31 1 ILl...VARlIER IV ISTE Figure 3. Geologic column 00 K 0 0 A~ V. 44 z u w LL0 s.- US LS C.) zo WECC; w0 0 Ř 4, + + +S + 4+ 03 4- + + z oO Z I 4- x 144 0

  3. Patrones de uso de sitios naturales y artificiales por Branta bernicla nigricans (Anseriformes: Anatidae en Guerrero Negro, Baja California Sur, México Habitat use patterns of the Black Brant Branta bernicla nigricans (Anseriformes: Anatidae in natural and artificial areas of Guerrero Negro, Baja California Sur, Mexico

    Directory of Open Access Journals (Sweden)

    Israel Martínez Cedillo

    2013-06-01

    Full Text Available En el complejo lagunar Guerrero Negro-Ojo de Liebre-Exportadora de Sal inverna el 31% de la población de Ganso de collar (Branta bernicla nigricans que utiliza México (31 000 aves en promedio. Nosotros realizamos censos de punto mensuales (noviembre 2006 a abril 2007 en tres sitios para determinar: (1 los efectos de la época del año y del sitio en la estructura poblacional (grupos de edad y (2 la relación del nivel de marea con la abundan- cia y la proporción de aves alimentándose. La proporción general de adultos fue de 0.68. Esta proporción fue mayor en invierno que en primavera. Por sitio en LGN y ESSA disminuyó y en LOL se mantuvo constante. El incremento de aves inmaduras entre el invierno y la primavera se relaciona con su partida primaveral tardía. La alimentación del Ganso de collar en LOL (el sitio de mayor abundancia fue independiente del nivel de marea, lo que se puede relacionar con dos conductas: (1 que las aves se muevan a lo largo de la laguna, para aprovechar el desfase, de hasta cuatro horas en el nivel de marea o (2 que modifiquen sus estrategias de alimentación, para consumir el pasto flotante.The Black Brant is a common inhabitant of the Western Artic American tundra, which migrates to Southern Pacific coasts during the winter season. Approximately, 31 000 birds (31% constitute the Mexican population of Brants at Guerrero Negro, Ojo de Liebre, and Exportadora de Sal lagoon complex; nevertheless, there is little information about the distribution patterns and zone usage. At Guerrero Negro Lagoon (GNL, Ojo de Liebre Lagoon (OLL, both natural sites, and at Exportadora de Sal (ESSA, artificial site we determined by monthly censuses (from November 2006 to April 2007, 08:00-16:00h and observed: (1 season and site effects on population structure (age groups, and (2 the tide level relationship with the abundance and proportion of feeding birds. Within a total of 150 observation hours and 98 birds, our results showed a

  4. ECOOL 1984

    International Nuclear Information System (INIS)

    Poth, H.

    1984-07-01

    These proceedings contain the articles presented at the named workshop. They deal with electron cooling and its applications, especially in heavy ion storage rings. See hints under the relevant topics. (HSI)

  5. Spectroscopy and Photometry of CAI-rich asteroids

    Science.gov (United States)

    Tanga, P.; Devogele, M.; Bendjoya, Ph.; Cellino, A.; Surdej, J.

    2017-09-01

    Asteroids with an anomalous amount of primitive elements, formed in ancient times in the solar nebula, exist. Our study confirms their nature and provides hints to the interpretation of the ancient evolution of asteroids.

  6. Calculus of variations mechanics, control and other applications

    CERN Document Server

    MacCluer, Charles R

    2012-01-01

    First truly up-to-date treatment offers a simple introduction to optimal control, linear-quadratic control design, and more. Broad perspective features numerous exercises, hints, outlines, and appendixes, including a practical discussion of MATLAB. 2005 edition.

  7. No Appetite? How to Get Nutrition during Cancer Treatment

    Science.gov (United States)

    ... than to eat something. During illness, treatment or recovery, your need for calories and protein may be ... patient-education/eating-hints. Accessed Jan. 5, 2015. Nutrition in cancer care (PDQ). National Cancer Institute. http:// ...

  8. Shiftwork Scheduling for the 1990s.

    Science.gov (United States)

    Coleman, Richard M.

    1989-01-01

    The author discusses the problems of scheduling shift work, touching on such topics as employee desires, health requirements, and business needs. He presents a method for developing shift schedules that addresses these three areas. Implementation hints are also provided. (CH)

  9. Experiments at CERN in 1981

    International Nuclear Information System (INIS)

    1981-08-01

    This report contains the preliminary abstracts of the current experiments at the CERN SPS synchrotron, the anti p colliding beams, the CERN ISR, the CERN PS synchrotron, and the CERN synchrocyclotron. See hints under the relevant topics. (HSI)

  10. Fulltext PDF

    Indian Academy of Sciences (India)

    Madhu

    humans and animals against excessive pulmonary pressures and prevent the occurrence of .... Natural stimulation of J receptors produces dry cough in addition to .... committees and meetings his eyes would blaze with anger at the first hint of ...

  11. Crystal Ball contributions to the 9th international workshop on photon-photon collisions, La Jolla, 23-26 March 1992

    International Nuclear Information System (INIS)

    Bienlein, J.K.

    1992-06-01

    This report contains two articles concerning new Crystal Ball data on resonance formation by γγ collisions and the representation of such results by helicity amplitudes. See hints under the relevant topics. (HSI)

  12. Res Publica hakkab kaaluma Kohtla-Järve võimuliidust lahkumist / Erik Gamzejev

    Index Scriptorium Estoniae

    Gamzejev, Erik, 1967-

    2002-01-01

    Ilmunud ka: Severnoje Poberezhje 19. nov. lk. 1. Res Publica eestseisuse ettepanek Kohtla-Järve osakonnale lahkuda koalitsioonist. Osakonna juhatuse otsus esitada Hants Hint volikogu esimehe kandidaadiks. Res Publica liikmete käitumise arutelu aukohtus

  13. Tracking Code for Microwave Instability

    International Nuclear Information System (INIS)

    Heifets, S.; SLAC

    2006-01-01

    To study microwave instability the tracking code is developed. For bench marking, results are compared with Oide-Yokoya results [1] for broad-band Q = 1 impedance. Results hint to two possible mechanisms determining the threshold of instability

  14. Gross properties of nuclei and nuclear excitations XXI

    International Nuclear Information System (INIS)

    Feldmeier, H.

    1993-01-01

    These proceedings contain the articles and contributed papers presented at the named workshop. They are concerned with highly excited nuclear matter and relativistic heavy ion reactions together with some related topics. See hints under the relevant topics. (HSI)

  15. Are demand forecasting techniques applicable to libraries?

    OpenAIRE

    Sridhar, M. S.

    1984-01-01

    Examines the nature and limitations of demand forecasting, discuses plausible methods of forecasting demand for information, suggests some useful hints for demand forecasting and concludes by emphasizing unified approach to demand forecasting.

  16. Trichoepithelioma And Multiple Basal Cell Epithelioma

    Directory of Open Access Journals (Sweden)

    Dey S.K

    1996-01-01

    Full Text Available A combination of multiple trichoepithelioma and basal cell epithelioma is reported. Although malignant degeneration of trichoepithelioma is debated, clinical and histopathological studies, in our case, hint at that. The case is reported for its rarity.

  17. Teaduste akadeemias austati Ahrensit / Allar Viivik

    Index Scriptorium Estoniae

    Viivik, Allar

    2015-01-01

    Eesti Teaduste Akadeemia saalis toimus konverents "Kummardus Ahrensile", sõnavõttude ja ettekannetega anti ülevaade Kuusalu pastori Eduard Ahrensi keelemehetööst. Ettekandega esines ka keelemees Mati Hint

  18. 17 Human Resource Development and the Productivity of the Civil ...

    African Journals Online (AJOL)

    FIRST LADY

    2011-01-18

    Jan 18, 2011 ... Civil Service of Cross River State, Nigeria (Pp. 17-24). Egbe ... knowledge content an employee possesses is the quality of training and retraining the ... offered useful hints that ensured standards that eventually aided the final.

  19. Maximizing your teaching moment

    Science.gov (United States)

    ... may help to give your patient written or audiovisual resources before your meeting. This may help reduce ... As you are teaching, provide reinforcement for learning. Reinforce your ... Offer hints, tips, and strategies that you have gathered ...

  20. Johannes Hindi tütar Pille Pae : inimlik headus ei sõltu režiimist / Pille Pae ; interv. Anneli Ammas

    Index Scriptorium Estoniae

    Pae, Pille

    2006-01-01

    Desintegraatori juhi Johannes Hindi tütar Pille Pae vastab küsimustele, mis puudutavad tema isa armuandmispalve esitamist, isale toetusallkirjade kogumist, Arnold Rüütli suhteid Johannes Hindiga. Lisa: Kes oli Johannes Hint ja mis Desintegraator?

  1. Scattering of highly excited atoms

    International Nuclear Information System (INIS)

    Raith, W.

    1980-01-01

    Experimental methods to excite atomic beams into Rydberg states and the first results of collision experiments with such beams are reported. For further information see hints under relevant topics. (orig.) [de

  2. Impact of hydrogen onboard storage technologies on the performance of hydrogen fuelled vehicles: A techno-economic well-to-wheel assessment

    NARCIS (Netherlands)

    de Wit, M.P.; Faaij, A.P.C.

    2007-01-01

    Hydrogen onboard storage technologies form an important factor in the overall performance of hydrogen fuelled transportation, both energetically and economically. Particularly, advanced storage options such as metal hydrides and carbon nanotubes are often hinted favourable to conventional, liquid

  3. Report on the meeting of the working groups on neutron scattering applied to studying condensed matter, and neutron scattering and complementary methods applied in chemistry and biology

    International Nuclear Information System (INIS)

    1985-06-01

    The present volume consists of 55 lectures. The subjects are: 1) Elastic neutron diffraction, 2) Lattice dynamics, 3) Diffusion, 4) Polymers, 5) Biology, 6) Methods and tools, 7) Magnetism. For distinct papers see hints under relevant topics. (BHO)

  4. Users guide for the ANL IBM SPx

    Energy Technology Data Exchange (ETDEWEB)

    Gropp, W.; Lusk, E.

    1994-12-01

    This guide presents the features of the IBM SPx installed in the Mathematics and Computer Science Division at Argonne National Laboratory. The guide describes the available hardware and software, access policies, and hints for using the system productively.

  5. Kuidas Alfred Adler läks tülli Sigmund Freudiga / Aivar Kull

    Index Scriptorium Estoniae

    Kull, Aivar, 1955-

    1996-01-01

    Arvustus: Adler, Alfred. Inimesetundmine : Inimeste iseloomude peategurid ja nende areng / Tlk. Debora Hint. 2.tr. Tln. : Kupar, 1995. Vaata ka: Kull, Aivar. Kulli pilk. - Tartu : Ilmamaa, 2005, lk. 97-100

  6. Data processing framework for decision making

    DEFF Research Database (Denmark)

    Larsen, Jan

    The aim of the talk is * to provide insight into some of the issues in data processing and detection systems * to hint at possible solutions using statistical signal processing and machine learning methodologies...

  7. Can Biochemistry Usefully Guide the Search for Better Polymer Electrolytes?

    Directory of Open Access Journals (Sweden)

    J. Woods Halley

    2013-09-01

    Full Text Available I review some considerations that suggest that the biochemical products of evolution may provide hints concerning the way forward for the development of better electrolytes for lithium polymer batteries.

  8. Theory of elementary particles. Proceedings

    International Nuclear Information System (INIS)

    Luest, D.; Weigt, G.

    1994-03-01

    These proceedings contain most of the invited talks ans short communications presented at the named symposium. These concern developments in field theory in connection with string models, grand unification, and quantum gravity. See hints under the relevant topics. (HSI)

  9. SPSS for starters

    CERN Document Server

    Cleophas, Ton J

    2010-01-01

    This book contains all statistical tests relevant for starters on SPSS. Each test is explained using a data example from clinical practice along with the main tables of results with an accompanying text with interpretations of the results and hints.

  10. 80th Annual Meeting | Annual Meetings | Events | Indian Academy of ...

    Indian Academy of Sciences (India)

    Current status and future prospects of neutrino mass measurement. View presentation ... Business Meeting of Fellows. 17.00. High Tea ... Hints of 'Beyond Standard Model' cosmology in the cosmic microwave background. View presentation.

  11. evaluation of total annual costs of heat exchanger networks using

    African Journals Online (AJOL)

    user

    after solving the first problem using RPA based heat integration gave a minimum total annual cost (TAC) of $237, ... mathematical programming and non-RPA based Hint software. ... The concept of pinch analysis evolved over the years.

  12. Keeletammik sai järjekordse nimipuu / Kristi Ehrlich

    Index Scriptorium Estoniae

    Ehrlich, Kristi, 1979-

    2009-01-01

    Väike-Maarjas peetud Wiedemanni keelepäevast, kus pidas ettekande ka tänavune keeleauhinna laureaat, Ohio ülikooli professor Ilse Lehiste. Keelekonverentsist võttis osa ka keeleteadlane ja TLÜ emeriitprofessor Mati Hint

  13. An introduction to the theory of linear spaces

    CERN Document Server

    Shilov, Georgi E

    1975-01-01

    Introductory treatment offers a clear exposition of algebra, geometry, and analysis as parts of an integrated whole rather than separate subjects. Numerous examples illustrate many different fields, and problems include hints or answers. 1961 edition.

  14. An introduction to linear algebra and tensors

    CERN Document Server

    Akivis, M A; Silverman, Richard A

    1978-01-01

    Eminently readable, completely elementary treatment begins with linear spaces and ends with analytic geometry, covering multilinear forms, tensors, linear transformation, and more. 250 problems, most with hints and answers. 1972 edition.

  15. F. J. Wiedemanni keeleauhind on lakanud. Elagu F. J. Wiedemanni keeleauhind! / Eevi Ross

    Index Scriptorium Estoniae

    Ross, Eevi

    2003-01-01

    15-ndad ja viimased F. J. Wiedemanni Keeleauhinna Sihtasutuse laureaadid on Mati Hint ja Helju Vals, järgmisel aastal antakse välja esimene riiklik F. J. Wiedemanni keeleauhind Eesti Vabariigi peaministri poolt

  16. Email: pattuquayefio@ug.edu.gh

    African Journals Online (AJOL)

    Apusigah

    making. ... study, the article hints at possible implications of the co-optation of human ... shortage, health challenges such as the Human Immunodeficiency Virus (HIV), and the causes ... appropriate framework for considering such challenges.

  17. Association between intimate partner violence & HIV/AIDS: Exploring the pathways in Indian context

    Directory of Open Access Journals (Sweden)

    Seema Patrikar

    2017-01-01

    Interpretation & conclusions: Significantly higher reporting of HIV/STIs by women experiencing IPV hints at new pathways that link violence and HIV. Further, our analysis showed a high prevalence of IPV in India.

  18. The International Criminal Court: Why We Need It, How We Got It, Our Concern About It

    National Research Council Canada - National Science Library

    MacCuish, Donald A; Hater, David A; Dubriske, Steven D; Ruby, Tomislav

    2005-01-01

    ... extreme. The problem with judicial proceedings is that they can have a hint of victor's justice, especially if the jurisdiction, legitimacy, and authority of the court are not established in advance...

  19. The amateur astronomer

    CERN Document Server

    Moore, Patrick

    2006-01-01

    Introduces astronomy and amateur observing together. This edition includes photographs and illustrations. The comprehensive appendices provide hints and tips, as well as data for every aspect of amateur astronomy. This work is useful for amateur astronomers

  20. Communicating with the Public: Getting It into Print.

    Science.gov (United States)

    Dyal, Donald

    1988-01-01

    Discusses the advantages for libraries of utilizing print media for public information and public relations. News releases, interest stories, and feature stories are described, and hints on writing style for each format and on getting items printed are offered. (MES)

  1. Isolation, characterization, and antibiotic resistance of Vibrio spp. in sea turtles from Northwestern Mexico

    Science.gov (United States)

    Zavala-Norzagaray, Alan A.; Aguirre, A. Alonso; Velazquez-Roman, Jorge; Flores-Villaseñor, Héctor; León-Sicairos, Nidia; Ley-Quiñonez, C. P.; Hernández-Díaz, Lucio De Jesús; Canizalez-Roman, Adrian

    2015-01-01

    The aerobic oral and cloacal bacterial microbiota and their antimicrobial resistance were characterized for 64 apparently healthy sea turtles captured at their foraging grounds in Ojo de Liebre Lagoon (OLL), Baja California Sur (BCS), Mexico (Pacific Ocean) and the lagoon system of Navachiste (LSN) and Marine Area of Influence (MAI), Guasave, Sinaloa (Gulf of California). A total of 34 black turtles (Chelonia mydas agassizii) were sampled in OLL and eight black turtles and 22 olive ridley turtles (Lepidochelys olivacea) were sampled in LSN and MAI, respectively from January to December 2012. We isolated 13 different species of Gram-negative bacteria. The most frequently isolated bacteria were Vibrio alginolyticus in 39/64 (60%), V. parahaemolyticus in 17/64 (26%), and V. cholerae in 6/64 (9%). However, V. cholerae was isolated only from turtles captured from the Gulf of California (MAI). Among V. parahaemolyticus strains, six O serogroups and eight serovars were identified from which 5/17 (29.4%) belonged to the pathogenic strains (tdh+ gene) and 2/17 (11.7%) had the pandemic clone (tdh+ and toxRS/new+). Among V. cholerae strains, all were identified as non-O1/non-O139, and in 4/6 (66%) the accessory cholera enterotoxin gene (ace) was identified but without virulence gene zot, ctxA, and ctxB. Of the isolated V. parahaemolyticus, V. cholerae, and V. alginolyticus strains, 94.1, 33.4, and 100% demonstrated resistance to at least one commonly prescribed antibiotic (primarily to ampicillin), respectively. In conclusion, the presence of several potential (toxigenic) human pathogens in sea turtles may represent transmission of environmental microbes and a high-risk of food-borne disease. Therefore, based on the fact that it is illegal and unhealthy, we discourage the consumption of sea turtle meat or eggs in northwestern Mexico. PMID:26161078

  2. Isolation, Characterization, and Antibiotic Resistance of Vibrio spp. in Sea Turtles from Northwestern Mexico

    Directory of Open Access Journals (Sweden)

    Alan A. eZavala-Norzagaray

    2015-06-01

    Full Text Available The aerobic oral and cloacal bacterial microbiota and their antimicrobial resistance were characterized for 64 apparently healthy sea turtles captured at their foraging grounds in Ojo de Liebre Lagoon (OLL, Baja California Sur, Mexico (Pacific Ocean and the lagoon system of Navachiste (LSN and Marine Area of Influence (MAI, Guasave, Sinaloa (Gulf of California. A total of 34 black turtles (Chelonia mydas agassizii were sampled in OLL and eight black turtles and 22 olive ridley turtles (Lepidochelys olivacea were sampled in LSN and MAI, respectively from January to December 2012. We isolated 13 different species of Gram-negative bacteria. The most frequently isolated bacteria were Vibrio alginolyticus in 39/64 (60%, V. parahaemolyticus in 17/64 (26% and V. cholerae in 6/64 (9%,. However, V. cholerae was isolated only from turtles captured from the Gulf of California (MAI. Among V. parahaemolyticus strains, six O serogroups and eight serovars were identified from which 5/17 (29.4% belonged to the pathogenic strains (tdh+ gene and 2/17 (11.7% had the pandemic clone (tdh+ and toxRS/new+. Among V. cholerae strains, all were identified as non-O1/non-O139, and in 4/6 (66% the accessory cholera enterotoxin gene (ace was identified but without virulence gene zot, ctxA and ctxB. Of the isolated V. parahaemolyticus, V. cholerae and V. alginolyticus strains, 94.1%, 33.4% and 100% demonstrated resistance to at least one commonly prescribed antibiotic (primarily to ampicillin, respectively. In conclusion, the presence of several potential (toxigenic human pathogens in sea turtles may represent transmission of environmental microbes and a high-risk of food-borne disease. Therefore, based on the fact that it is illegal and unhealthy, we discourage the consumption of sea turtle meat or eggs in northwestern Mexico.

  3. Isolation, characterization, and antibiotic resistance of Vibrio spp. in sea turtles from Northwestern Mexico.

    Science.gov (United States)

    Zavala-Norzagaray, Alan A; Aguirre, A Alonso; Velazquez-Roman, Jorge; Flores-Villaseñor, Héctor; León-Sicairos, Nidia; Ley-Quiñonez, C P; Hernández-Díaz, Lucio De Jesús; Canizalez-Roman, Adrian

    2015-01-01

    The aerobic oral and cloacal bacterial microbiota and their antimicrobial resistance were characterized for 64 apparently healthy sea turtles captured at their foraging grounds in Ojo de Liebre Lagoon (OLL), Baja California Sur (BCS), Mexico (Pacific Ocean) and the lagoon system of Navachiste (LSN) and Marine Area of Influence (MAI), Guasave, Sinaloa (Gulf of California). A total of 34 black turtles (Chelonia mydas agassizii) were sampled in OLL and eight black turtles and 22 olive ridley turtles (Lepidochelys olivacea) were sampled in LSN and MAI, respectively from January to December 2012. We isolated 13 different species of Gram-negative bacteria. The most frequently isolated bacteria were Vibrio alginolyticus in 39/64 (60%), V. parahaemolyticus in 17/64 (26%), and V. cholerae in 6/64 (9%). However, V. cholerae was isolated only from turtles captured from the Gulf of California (MAI). Among V. parahaemolyticus strains, six O serogroups and eight serovars were identified from which 5/17 (29.4%) belonged to the pathogenic strains (tdh (+) gene) and 2/17 (11.7%) had the pandemic clone (tdh (+) and toxRS/new (+)). Among V. cholerae strains, all were identified as non-O1/non-O139, and in 4/6 (66%) the accessory cholera enterotoxin gene (ace) was identified but without virulence gene zot, ctxA, and ctxB. Of the isolated V. parahaemolyticus, V. cholerae, and V. alginolyticus strains, 94.1, 33.4, and 100% demonstrated resistance to at least one commonly prescribed antibiotic (primarily to ampicillin), respectively. In conclusion, the presence of several potential (toxigenic) human pathogens in sea turtles may represent transmission of environmental microbes and a high-risk of food-borne disease. Therefore, based on the fact that it is illegal and unhealthy, we discourage the consumption of sea turtle meat or eggs in northwestern Mexico.

  4. Fatty acid and triacylglycerol composition of the subcutaneous fat from iberian pigs fattened on the traditional feed: “Montanera”. effect of anatomical location and length of feeding

    Directory of Open Access Journals (Sweden)

    Narváez-Rivas, Mónica

    2009-07-01

    Full Text Available Fatty acid and triacylglycerol compositions of 200 samples of subcutaneous fat from two different anatomical locations (rump and adipose tissue covering the Biceps femoris muscle of Iberian purebred pigs reared on “Montanera” were determined. Significant differences were found for the majority fatty acids and for some triacylglycerol species (PPS, PLPo + MLO, PLO, PLL + PoLO, SOS, SOL, OLL among the two anatomical locations, being the rump location less saturated. The activity level of the key enzyme involved in lipogenesis differed (p Biceps femoris, increases faster than that of the subcutaneous fat covering a muscle with low oxidative metabolism, as Longissimus dorsi.Se ha determinado la composición de ácidos grasos y de triglicéridos en 200 muestras de grasa subcutánea procedentes de dos localizaciones anatómicas (rabadilla y tejido adiposo que recubre el músculo Biceps femoris de cerdos ibéricos puros alimentados en “Montanera”. Se encontraron diferencias significativas para la mayoría de ácidos grasos y para algunos triglicéridos PPS, PLPo + MLO, PLO, PLL + PoLO, SOS, SOL, OLL entre las dos localizaciones anatómicas, siendo la rabadilla la menos saturada. El nivel de actividad de la enzima involucrada en la lipogénesis defirió significativamente (p B. femoris, aumenta más rápidamente que la de la grasa subcutánea que recubre un músculo con bajo metabolismo oxidativo, como el Longissimus dorsi.

  5. Translations on USSR Military Affairs, Number 1328.

    Science.gov (United States)

    1978-02-02

    of his age. This news came as no surprise to Mikhail Vasil’yevich, and he reported to the commander his readiness immediately to begin the transfer...for this period, in which regard he dropped a hint to the commander. 103 Major Labushev did not take the hint. Convinced that there was no mutual...District. It was directed thence to the garrison judge advocate, who sent Mikhail Vasil’yevich an encouraging letter. It declared that his unit

  6. Generation of Tutorial Dialogues: Discourse Strategies for Active Learning

    Science.gov (United States)

    1998-05-29

    AND SUBTITLE Generation of Tutorial Dialogues: Discourse Strategies for active Learning AUTHORS Dr. Martha Evens 7. PERFORMING ORGANI2ATION NAME...time the student starts in on a new topic. Michael and Rovick constantly attempt to promote active learning . They regularly use hints and only resort...Controlling active learning : How tutors decide when to generate hints. Proceedings of FLAIRS 󈨣. Melbourne Beach, FL. 157-161. Hume, G., Michael

  7. From the standard model to dark matter

    International Nuclear Information System (INIS)

    Wilczek, F.

    1995-01-01

    The standard model of particle physics is marvelously successful. However, it is obviously not a complete or final theory. I shall argue here that the structure of the standard model gives some quite concrete, compelling hints regarding what lies beyond. Taking these hints seriously, one is led to predict the existence of new types of very weakly interacting matter, stable on cosmological time scales and produced with cosmologically interesting densities--that is, ''dark matter''. copyright 1995 American Institute of Physics

  8. Reseach blog:

    DEFF Research Database (Denmark)

    Lieberoth, Andreas

    2011-01-01

    Ongoing research blog discussing Andreas' research in the psychology of applied games, as well as general musings on cognitive neuroscience, game-design, and more. Also contains hints and guides for students on writing psychology research-papers.......Ongoing research blog discussing Andreas' research in the psychology of applied games, as well as general musings on cognitive neuroscience, game-design, and more. Also contains hints and guides for students on writing psychology research-papers....

  9. Towards high-density matter with relativistic heavy-ion collisions

    International Nuclear Information System (INIS)

    Nagamiya, Shoji.

    1990-04-01

    Recent progress in nucleus-nucleus collisions at BNL and CERN suggests a hint that the formation of high-density nuclear matter could be possible with relativistic heavy-ion beams. What is the maximum density that can be achieved by heavy-ion collisions? Are there data which show evidence or hints on the formation of high density matter? Why is the research of high-density interesting? How about the future possibilities on this subject? These points are discussed. (author)

  10. Sense of Accomplishment Is Modulated by a Proper Level of Instruction and Represented in the Brain Reward System.

    Science.gov (United States)

    Nakai, Tomoya; Nakatani, Hironori; Hosoda, Chihiro; Nonaka, Yulri; Okanoya, Kazuo

    2017-01-01

    Problem-solving can be facilitated with instructions or hints, which provide information about given problems. The proper amount of instruction that should be provided for learners is controversial. Research shows that tasks with intermediate difficulty induce the largest sense of accomplishment (SA), leading to an intrinsic motivation for learning. To investigate the effect of instructions, we prepared three instruction levels (No hint, Indirect hint, and Direct hint) for the same insight-problem types. We hypothesized that indirect instructions impose intermediate difficulty for each individual, thereby inducing the greatest SA per person. Based on previous neuroimaging studies that showed involvement of the bilateral caudate in learning and motivation, we expected SA to be processed in this reward system. We recruited twenty-one participants, and investigated neural activations during problem solving by functional magnetic resonance imaging (fMRI). We confirmed that the Indirect hint, which imposed intermediate difficulty, induced the largest SA among the three instruction types. Using fMRI, we showed that activations in the bilateral caudate and anterior cingulate cortex (ACC) were significantly modulated by SA. In the bilateral caudate, the indirect hint induced the largest activation, while the ACC seemed to reflect the difference between correct and incorrect trials. Importantly, such activation pattern was independent of notations (number or letter). Our results indicate that SA is represented in the reward system, and that the Indirect instruction effectively induces such sensation.

  11. Tendenze interpuntorie in giovani narratori

    OpenAIRE

    Spinelli, Silvia

    2016-01-01

    Il saggio si concentra sull’analisi dei fenomeni interpuntori all’interno di alcuni romanzi scritti da giovani autori italiani e pubblicati dopo l’anno duemila: 100 colpi di spazzola prima di andare a dormire, di Melissa P. (2003), La ragazza dei miei sogni di Roberto Dimitri (2007), La solitudine dei numeri primi di Paolo Giordano (2008), La Panzanella di Giulia Villoresi (2009), Acciaio di Silvia Avallone (2010) e Troppa umana speranza di Alessandro Mari (2011). L’analisi comparata dei roma...

  12. Panel Discussion: Common Themes Across ``Bringing Newcomers Into The Physics Community''

    Science.gov (United States)

    Little, Angela

    2014-03-01

    I will be facilitating a discussion between the audience and the four speakers in this session: Dimitri Dounas-Frazer, Catherine Good, Casey Miller, and Katie Hinko. They will all be speaking on the same general topic of supporting newcomers to the physics community at critical transition points but come from a set of diverse contexts and perspectives. Their work spans a wide age range of STEM students and they approach their work through many different lenses: as physics faculty, program directors, education and psychology researchers, and combinations thereof. Broad themes across these contexts and perspectives will be explored such as the role of growth mindset, community, and professional development.

  13. Intersecting Itineraries Beyond the Strada Novissima: The Converging Authorship of Critical Regionalism

    Directory of Open Access Journals (Sweden)

    Stylianos Giamarelos

    2016-07-01

    Full Text Available While the 1980 Venice Biennale is usually understood as the exhibition that crystallised postmodernism as a style of historicist eclecticism, the event also acted as a catalyst for the eventual convergence of alternative architectural sensibilities and ideas. This article shows how critical regionalism emerged when the physical and intellectual trajectories of British historian Kenneth Frampton and the Greek architects Suzana Antonakaki and Dimitris Antonakakis intersected in the aftermath of the Biennale. Offering an alternative way out of the contemporaneous crisis of modernism, this open-ended and extrovert regionalism that opposed static cultural insularities is thus the discursive footprint of architectural sensibilities travelling through cultures.

  14. Pitfalls and Rewards for Implementing Ocular Motor Testing in Acute Vestibular Syndrome: A Pilot Project.

    Science.gov (United States)

    Dumitrascu, Oana M; Torbati, Sam; Tighiouart, Mourad; Newman-Toker, David E; Song, Shlee S

    2017-03-01

    Isolated acute vestibular syndrome (iAVS) presentations to the emergency department (ED) pose management challenges, given the concerns for posterior circulation strokes. False-negative brain imaging may erroneously reassure clinicians, whereas HINTS-plus examination outperforms imaging to screen for strokes in iAVS. We studied the feasibility of implementing HINTS-plus testing in the ED, aiming to reduce neuroimaging in patients with iAVS. We launched an institutional Quality Improvement initiative, using DMAIC methodology. The outcome measures [proportion of iAVS subjects who had HINTS-plus examinations and underwent neuroimaging by computed tomography/magnetic resonance imaging (CT/MRI)] were compared before and after the established intervention. The intervention consisted of formal training for neurologists and emergency physicians on how to perform, document, and interpret HINTS-plus and implementation of novel iAVS management algorithm. Neuroimaging was not recommended if HINTS-plus suggested peripheral vestibular etiology. If a central process was suspected, brain MRI/MR angiogram was performed. Head CT was reserved only for thrombolytic time-window cases. In the first 2 months postimplementation, HINTS-plus testing performance by neurologists increased from 0% to 80% (P=0.007), and by ED providers from 0% to 9.09% (P=0.367). Head CT scans were reduced from 18.5% to 6.25%. Brain MRI use was reduced from 51.8% to 31.2%. About 60% of the iAVS subjects were discharged from the ED; none were readmitted or had another ED presentation in the ensuing 30 days. Implementation of HINTS-plus evaluation in the ED is valuable and feasible for neurologists, but challenging for emergency physicians. Future studies should determine the "dose-response" curve of educational interventions.

  15. Angioid streaks, clinical course, complications, and current therapeutic management

    Directory of Open Access Journals (Sweden)

    Ilias Georgalas

    2008-12-01

    Full Text Available Ilias Georgalas1, Dimitris Papaconstantinou2, Chrysanthi Koutsandrea2, George Kalantzis2, Dimitris Karagiannis2, Gerasimos Georgopoulos2, Ioannis Ladas21Department of Ophthalmology, “G. Gennimatas” Hospital of Athens, NHS, Athens, Greece; 2Department of Ophthalmology, “G. Gennimatas” Hospital of Athens, University of Athens, Athens, GreeceAbstract: Angioid streaks are visible irregular crack-like dehiscences in Bruch’s membrane that are associated with atrophic degeneration of the overlying retinal pigmented epithelium. Angioid streaks may be associated with pseudoxanthoma elasticum, Paget’s disease, sickle-cell anemia, acromegaly, Ehlers–Danlos syndrome, and diabetes mellitus, but also appear in patients without any systemic disease. Patients with angioid streaks are generally asymptomatic, unless the lesions extend towards the foveola or develop complications such as traumatic Bruch’s membrane rupture or macular choroidal neovascularization (CNV. The visual prognosis in patients with CNV secondary to angioid streaks if untreated, is poor and most treatment modalities, until recently, have failed to limit the devastating impact of CNV in central vision. However, it is likely that treatment with antivascular endothelial growth factor, especially in treatment-naive eyes to yield favorable results in the future and this has to be investigated in future studies.Keywords: angioid streaks, pseudoxanthoma elasticum, choroidal neovascularization

  16. Oxygen transport enhancement by functionalized magnetic nanoparticles (FMP) in bioprocesses

    Science.gov (United States)

    Ataide, Filipe Andre Prata

    The enhancement of fluid properties, namely thermal conductivity and mass diffusivity for a wide range of applications, through the use of nanosized particles' suspensions has been gathering increasing interest in the scientific community. In previous studies, Olle et al. (2006) showed an enhancement in oxygen absorption to aqueous solutions of up to 6-fold through the use of functionalized nanosized magnetic particles with oleic acid coating. Krishnamurthy et al. (2006) showed a remarkable 26-fold enhancement in dye diffusion in water. These two publications are landmarks in mass transfer enhancement in chemical systems through the use of nanoparticles. The central goal of this Ph.D. thesis was to develop functionalized magnetic nanoparticles to enhance oxygen transport in bioprocesses. The experimental protocol for magnetic nanoparticles synthesis and purification adopted in this thesis is a modification of that reported by Olle et al. (2006). This is facilitated by employing twice the quantity of ammonia, added at a slower rate, and by filtering the final nanoparticle solution in a cross-flow filtration modulus against 55 volumes of distilled water. This modification in the protocol resulted in improved magnetic nanoparticles with measurably higher mass transfer enhancement. Magnetic nanoparticles with oleic acid and Hitenol-BC coating were screened for oxygen transfer enhancement, since these particles are relatively inexpensive and easy to synthesize. A glass 0.5-liter reactor was custom manufactured specifically for oxygen transport studies in magnetic nanoparticles suspensions. The reactor geometry, baffles and Rushton impeller are of standard dimensions. Mass transfer tests were conducted through the use of the sulphite oxidation method, applying iodometric back-titration. A 3-factor central composite circumscribed design (CCD) was adopted for design of experiments in order to generate sufficiently informative data to model the effect of magnetic

  17. Light weakly interacting massive particles

    Science.gov (United States)

    Gelmini, Graciela B.

    2017-08-01

    Light weakly interacting massive particles (WIMPs) are dark matter particle candidates with weak scale interaction with the known particles, and mass in the GeV to tens of GeV range. Hints of light WIMPs have appeared in several dark matter searches in the last decade. The unprecedented possible coincidence into tantalizingly close regions of mass and cross section of four separate direct detection experimental hints and a potential indirect detection signal in gamma rays from the galactic center, aroused considerable interest in our field. Even if these hints did not so far result in a discovery, they have had a significant impact in our field. Here we review the evidence for and against light WIMPs as dark matter candidates and discuss future relevant experiments and observations.

  18. "Don't know" responses to risk perception measures: implications for underserved populations.

    Science.gov (United States)

    Waters, Erika A; Hay, Jennifer L; Orom, Heather; Kiviniemi, Marc T; Drake, Bettina F

    2013-02-01

    Risk perceptions are legitimate targets for behavioral interventions because they can motivate medical decisions and health behaviors. However, some survey respondents may not know (or may not indicate) their risk perceptions. The scope of "don't know" (DK) responding is unknown. Examine the prevalence and correlates of responding DK to items assessing perceived risk of colorectal cancer. Two nationally representative, population-based, cross-sectional surveys (2005 National Health Interview Survey [NHIS]; 2005 Health Information National Trends Survey [HINTS]), and one primary care clinic-based survey comprised of individuals from low-income communities. Analyses included 31,202 (NHIS), 1,937 (HINTS), and 769 (clinic) individuals. Five items assessed perceived risk of colorectal cancer. Four of the items differed in format and/or response scale: comparative risk (NHIS, HINTS); absolute risk (HINTS, clinic), and "likelihood" and "chance" response scales (clinic). Only the clinic-based survey included an explicit DK response option. "Don't know" responding was 6.9% (NHIS), 7.5% (HINTS-comparative), and 8.7% (HINTS-absolute). "Don't know" responding was 49.1% and 69.3% for the "chance" and "likely" response options (clinic). Correlates of DK responding were characteristics generally associated with disparities (e.g., low education), but the pattern of results varied among samples, question formats, and response scales. The surveys were developed independently and employed different methodologies and items. Consequently, the results were not directly comparable. There may be multiple explanations for differences in the magnitude and characteristics of DK responding. "Don't know" responding is more prevalent in populations affected by health disparities. Either not assessing or not analyzing DK responses could further disenfranchise these populations and negatively affect the validity of research and the efficacy of interventions seeking to eliminate health disparities.

  19. Chemical characterization and thermal properties of kernel oils from Tunisian peach and nectarine varieties of Prunus persica; Caracterización química y propiedades térmicas de los aceites de semillas de variedades tunecinas de melocotón y nectarina de Prunus pérsica

    Energy Technology Data Exchange (ETDEWEB)

    Chamli, D.; Bootello, M.A.; Bouali, I.; Jouhri, S.; Boukhchina, S.; Martínez-Force, S.

    2017-07-01

    A comparative study was conducted to determine the fatty acids, triacylglycerol compositions and thermal properties of Tunisian kernel oils from the Prunus persica varieties, peach and nectarine, grown in two areas of Tunisia, Gabes and Morneg. Qualitatively, the fatty acids composition and triacylglycerol species were identical for all samples. Oleic acid (67.7-75.0%) was the main fatty acid, followed by linoleic (15.7-22.1%) and palmitic (5.6-6.3%) acids. The major triacylglycerol species were triolein, OOO (38.4-50.5%), followed by OOL (18.2-23.2%), POO (8.3-9.7%) and OLL (6.3-10.1%). The thermal profiles were highly influenced by the high content of triolein due to the importance of oleic acid in these oils. Moreover, the fatty acids distribution in TAG external positions was determined as corresponding to an α asymmetry coefficient that was between 0.10 and 0.12, indicating a high asymmetry in the distribution of saturated fatty acids in the position sn-1 and sn-3 in the TAG species of all samples. [Spanish] Se ha realizado un estudio comparativo de aceites tunecinos obtenidos a partir de las semillas de variedades de Prunus persica, melocotón y nectarina, cultivadas en dos zonas de Túnez, Gabes y Morneg. Cualitativamente, la composición de ácidos grasos y de especies de triglicéridos fueron idénticas para todas las muestras. El ácido oleico (67,7-75,0%) fue el ácido graso principal, seguido del linoleico (15,7-22,1%) y el palmítico (5,6-6,3%). Las especies principales de triacilglicéridos fueron la trioleina, OOO (38,4-50,5%), seguida de OOL (18,2-23,2%), POO (8,3-9,7%) y OLL (6,3-10,1%). Los perfiles térmicos fueron muy influidos por el alto contenido de trioleina debido a la importancia del ácido oleico en estos aceites. Por otra parte, se determinó la distribución de ácidos grasos en las posiciones externas de los TAG correspondiendo a un coeficiente de asimetría α entre 0,10 y 0,12, lo que indica una alta asimetría en la distribuci

  20. Joint statement by the chairmen of the Standing Committee on Reactors and the Reactor Safety Commission on safety-related documents drawn up under the Franco-German Commission on Safety Questions for Nuclear Installations (DFK). August 29, 1986

    International Nuclear Information System (INIS)

    1986-01-01

    The report contains: 1. The present situation regarding hints and recommendations in the safety declaration by the TUEV Baden on the subject of Cattenom nuclear power station in June 1982. 2. The present situation regarding hints and recommendations in the declaration by the TUEV Rhineland in February 1982 on the subject of radiological aspects and features of the Cattenom site for the nuclear power plant. 3. Answers to press allegations about the safety of Cattenom NPP: scram system, safety cooling system, heat sink for after-heat removal, emergency power supplies, load-follow operation, air crashes, susceptibility to failures. (orig./HP) [de