Is Dieting OK for Kids?

Science.gov (United States)

... First Aid & Safety Doctors & Hospitals Videos Recipes for Kids Kids site Sitio para niños How the Body ... Educators Search English Español Is Dieting OK for Kids? KidsHealth / For Kids / Is Dieting OK for Kids? ...

Minor corral changes and adoption of good handling practices can improve the behavior and reduce cortisol release in Nellore cows.

Science.gov (United States)

Lima, Maria Lúcia Pereira; Negrão, João Alberto; de Paz, Claudia Cristina Paro; Grandin, Temple

2018-03-01

Inadequate corral facilities and improper handling are major causes of stress in beef cattle. The purpose of this study was to evaluate the effects of minor changes in the corral and adoption of good handling practices on the behavior, cortisol release, and time spent taking blood samples in Nellore cows. Minor corral changes included obstructing the cow's vision when the handler walked deep into the animal's flight zone and the elimination of bright objects, color contrasts, puddles, shadows, and darkness in the corral. Handling was improved by eliminating dogs, electric goads (prods), and yelling, as well as adopting a calm behavior. A total of 141 Nellore cows from two typical extensive livestock farms were studied. The cows were evaluated individually before and after the corral changes. Blood samples were collected in the restraint device for cortisol measurement. The minor corral changes and the adoption of good handling practices result in better results for all variables studied. The results showed differences in the interactions between treatment and ranch for chute score (P = 0.0091) and exit score (P good handling practices were effective in improving cow behavior in the chute and in reducing exit velocity, cortisol released, and the time spent taking blood samples.

Authenticity and origin of prehispanic ceramic material, analysis of zapotecan urns of the Ontario Real Museum

International Nuclear Information System (INIS)

Ramirez L, A.; Schaaf, P.; Martinez, Y.; Ortiz D, E.; Lazos, L.; Ruvalcaba, J.L.; Sellen, A.

2003-01-01

The Zapotec culture flourished approximately in Oaxaca of the year 220 B.C. up to the 800 D.C., in their funeral acts the Zapotec often took to the tomb to their deads accompanied of rich offerings including a great variety of ceramic, one of these varieties of ceramics were those urns that are kind of an adorned vessels with a sphinx, that is to say, a cylinder that has incorporate a figure generally anthropomorphous, which represented ancestres or divinities, the size of these urns went from the 15 cm until but of a meter high. At the beginning of the XX century the urns got the attention of the collectors and a number important of replies (false) they were manufactured copying the original ones, in this time C. Rickards gathers one of those but important collections of urns zapotec, in 1919 the Real Museum of Ontario (ROM) acquired the collection Rickards, in the 70 s they were practiced test of authenticity for thermoluminescence indicating that 36 of these urns were false, comparing their iconography with the other urns of the collection suggests the possibility that at least 80 of these pieces are not you authenticate. In this work the results are presented by thermoluminescence carried out to 17 pieces of the collection Rickards property of the Real Museum of Ontario like part of a first one work stage, for they were perforated it the urns with a drill of tungsten carbide extracting 50 milligrams approximately, of which 25 were used for thermoluminescence and the rest for analysis for X ray Emission Spectroscopy. Proton Induced X-ray Emission (PIXE) and for X-ray Diffraction (XRD). The test of authenticity for thermoluminescence beginning with the determination of the rate of annual dose starting from the determination of the concentration of the natural radioisotopes of uranium ( 238 U) and torio ( 232 Th) by means of an accountant of particles alpha, the potassium ( 40 K) by means of X-ray diffraction, later on the sample was treated chemically with

Linfangioma cervical: manejo terapéutico con OK-432 (Picibanil Cervical lymphangioma: therapeutic management with OK-432 (Picibanil

Directory of Open Access Journals (Sweden)

E. Valle Rodríguez

2007-12-01

Full Text Available Introducción: El linfangioma es una malformación del sistema linfático. El abordaje clásico ha sido la cirugía. El OK-432 (Picibanil tiene acción esclerosante y se está utilizando cómo primer escalón terapéutico. El objetivo es aportar un nuevo caso de linfangioma tratado con OK-432 y hacer una revisión de la literatura. Material y método: Aportamos un varón de 16 años con un linfangioma cervical macroquístico de 10 x 6 cm tratado con una dosis de OK-432. Resultados: A las 16 semanas del tratamiento, el tamaño del linfangioma era de 6 x 2 cm, siendo clínicamente inapreciable. Discusión: El tratamiento con OK-432 tiene una alta tasa de curación, con una baja tasa de recidiva y una fibrosis circunscrita a la lesión. En relación con la cirugía, se evitan cicatrices y posibles lesiones de estructuras vitales.Introduction: Lymphangioma is a malformation of the lymphatic system. The classic approach is surgery. OK-432 (Picibanil has sclerosing action and is being used as the first therapeutic step. The objective was to report a new case of lymphangioma treated with OK-432 and to review the literature. Material and method: We report the case of a 16-year-old man with a 10x6-cm macrocystic cervical lymphangioma treated with a dose of OK-432. Results: At 16 weeks of treatment, the size of the lymphangioma was 6x2 cm and it was clinically unappreciable. Discussion: OK-432 treatment has a high cure rate, low recurrence rate, and fibrosis circumscribed to the lesion. Compared to surgery, scars and possible harm to vital structures are avoided.

Trap and corral: a two-step approach for constructing and constraining dynamic cell contact events in differentiating progenitor cell populations

International Nuclear Information System (INIS)

Chen, S; Patel, N; Schaffer, D; Maharbiz, M M

2011-01-01

Cells are constantly subjected to a host of external signals which can influence their state, phenotype and behavior. Mammalian cells are dependent on signals from surrounding cells to maintain viability, proliferate and coordinate their actions. During developmental and regenerative processes, these lateral signals between cells provide instructive cues informing stem cells how, when and where to differentiate. Moreover, differentiating cells often experience cell–cell contact events interspersed with bouts of motility, process extension and multi-cell agglomeration (Gage 2000 Science 287 1433–8) processes which are not easily recapitulated in existing cell capture devices. Here, we present a two-step process involving microwells to trap cells with high efficiency followed by the alignment of a PDMS mesh around the cells to corral them after the trapping. The microwells trap single cells and paired cells with up to 90% and 80% efficiencies, respectively. After seeding, the PDMS mesh is aligned with the seeded wells to create a 150 µm × 150 µm corral around each trap, allowing cells to interact in a larger arena. The corralling must be done in liquid after seeding because the seeding requires high cell densities to achieve near-full occupancy in the wells. Low-density seeding of the PDMS corrals alone can result in two cells being trapped in each well, but in those conditions, the two cells often engage in very little contact or none at all (and seeding obeys a non-desirable Poisson distribution). Interestingly, trapping cells in proximity and then corralling them elicits much higher contact times than simply seeding into corrals

Žurnālista un viņa tiesību sargāt avotus definīcija Eiropas un starptautiskajās tiesībās

OpenAIRE

Šimkus, Anrijs

2015-01-01

Darba ietvaros autors pēta, kā mūsdienu starptautiskajās cilvēktiesībās ir definēts žurnālists. Autors konkrēti izvērtē divas žurnālista definēšanas teorijas, kuras sastopamas valstu un tiesu praksē. Pirmā ir institucionālā teorija, kas nosaka, ka žurnālistam jābūt saiknei ar profesionālu mediju vai žurnālistu organizāciju. Otrā ir funkcionālā teorija, kas nosaka, ka ikviena persona, kura pilda žurnālista funkcijas, būs žurnālists. Tāpat autors pēta, vai žurnālista galveno privilēģiju - tiesī...

Treatment of lymphangiomas with OK-432 (Picibanil).

Science.gov (United States)

Rautio, Riitta; Keski-Nisula, Leo; Laranne, Jussi; Laasonen, Erkki

2003-01-01

To determine the efficacy of OK-432 sclerotherapy in the treatment of lymphangiomas. The treatment was begun for 14 patients with lymphangioma. The age range of the patients at the time of the first injection was from 10 months to 42 years. Eleven of the lesions involved the head and neck region, two the thorax and one was localized in the extremity. Prior to treatment all patients were investigated with either magnetic resonance imaging, computed tomography, ultrasound or a combination of these modalities. The injections were performed with ultrasound and/or fluoroscopic guidance. Eight patients received OK-432 as first-line treatment; five were treated after surgery and one after medical therapy. On average, 2.2 intracystic injections were performed per patient. Nine of the lesions were macrocystic and five were mixed lesions. Eleven patients showed complete or marked response to the OK-432 sclerotherapy, two patients had moderate shrinkage of their lesions and only one patient showed no response to therapy. Macrocystic lesions showed the best response to therapy. Those patients who received OK-432 as first-line treatment showed complete or marked response. It was found that treatment of lymphangiomas with OK-432 was safe and effective.

Urns and Chameleons: two metaphors for two different types of measurements

International Nuclear Information System (INIS)

Accardi, Luigi

2013-01-01

The awareness of the physical possibility of models of space, alternative with respect to the Euclidean one, begun to emerge towards the end of the 19-th century. At the end of the 20-th century a similar awareness emerged concerning the physical possibility of models of the laws of chance alternative with respect to the classical probabilistic models (Kolmogorov model). In geometry the mathematical construction of several non-Euclidean models of space preceded of about one century their applications in physics, which came with the theory of relativity. In physics the opposite situation took place. In fact, while the first example of non Kolmogorov probabilistic models emerged in quantum physics approximately one century ago, at the beginning of 1900, the awareness of the fact that this new mathematical formalism reflected a new mathematical model of the laws of chance had to wait until the early 1980's. In this long time interval the classical and the new probabilistic models were both used in the description and the interpretation of quantum phenomena and negatively interfered with each other because of the absence (for many decades) of a mathematical theory that clearly delimited the respective domains of application. The result of this interference was the emergence of the so-called the p aradoxes of quantum theory . For several decades there have been many different attempts to solve these paradoxes giving rise to what K. Popper baptized t he great quantum muddle : a debate which has been at the core of the philosophy of science for more than 50 years. However these attempts have led to contradictions between the two fundamental theories of the contemporary physical: the quantum theory and the theory of the relativity. Quantum probability identifies the reason of the emergence of non Kolmogorov models, and therefore of the so-called the paradoxes of quantum theory, in the difference between the notion of passive measurements like 'reading pre

Overland flow connectivity on planar patchy hillslopes - modified percolation theory approaches and combinatorial model of urns

Science.gov (United States)

Nezlobin, David; Pariente, Sarah; Lavee, Hanoch; Sachs, Eyal

2017-04-01

Source-sink systems are very common in hydrology; in particular, some land cover types often generate runoff (e.g. embedded rocks, bare soil) , while other obstruct it (e.g. vegetation, cracked soil). Surface runoff coefficients of patchy slopes/plots covered by runoff generating and obstructing covers (e.g., bare soil and vegetation) depend critically on the percentage cover (i.e. sources/sinks abundance) and decrease strongly with observation scale. The classic mathematical percolation theory provides a powerful apparatus for describing the runoff connectivity on patchy hillslopes, but it ignores strong effect of the overland flow directionality. To overcome this and other difficulties, modified percolation theory approaches can be considered, such as straight percolation (for the planar slopes), quasi-straight percolation and models with limited obstruction. These approaches may explain both the observed critical dependence of runoff coefficients on percentage cover and their scale decrease in systems with strong flow directionality (e.g. planar slopes). The contributing area increases sharply when the runoff generating percentage cover approaches the straight percolation threshold. This explains the strong increase of the surface runoff and erosion for relatively low values (normally less than 35%) of the obstructing cover (e.g., vegetation). Combinatorial models of urns with restricted occupancy can be applied for the analytic evaluation of meaningful straight percolation quantities, such as NOGA's (Non-Obstructed Generating Area) expected value and straight percolation probability. It is shown that the nature of the cover-related runoff scale decrease is combinatorial - the probability for the generated runoff to avoid obstruction in unit area decreases with scale for the non-trivial percentage cover values. The magnitude of the scale effect is found to be a skewed non-monotonous function of the percentage cover. It is shown that the cover-related scale

Treatment of Lymphangiomas with OK-432 (Picibanil)

International Nuclear Information System (INIS)

Rautio, Riitta; Keski-Nisula, Leo; Laranne, Jussi; Laasonen, Erkki

2003-01-01

Purpose: To determine the efficacy of OK-432 sclerotherapy in the treatment of lymphangiomas. Methods: The treatment was begun for 14 patients with lymphangioma. The age range of the patients at the time of the first injection was from 10 months to 42 years. Eleven of the lesions involved the head and neck region, two the thorax and one was localized in the extremity. Prior to treatment all patients were investigated with either magnetic resonance imaging, computed tomography, ultrasound or a combination of these modalities. The injections were performed with ultrasound and/or fluoroscopic guidance. Eight patients received OK-432 as first-line treatment; five were treated after surgery and one after medical therapy. On average, 2.2 intracystic injections were performed per patient. Nine of the lesions were macrocystic and five were mixed lesions. Results: Eleven patients showed complete or marked response to the OK-432 sclerotherapy, two patients had moderate shrinkage of their lesions and only one patient showed no response to therapy. Macrocystic lesions showed the best response to therapy. Those patients who received OK-432 as first-line treatment showed complete or marked response. Conclusion: It was found that treatment of lymphangiomas with OK-432 was safe and effective

Computed Tomography and Computed Radiography of late Bronze Age Cremation Urns from Denmark

DEFF Research Database (Denmark)

Harvig, Lise Lock; Lynnerup, Niels; Amsgaard Ebsen, Jannie

2012-01-01

To improve methods used to study prehistoric cremation rituals, cremation urns from the Danish late Bronze Age were examined using Computed Tomography and Computed Radiography (Digital X-ray). During microexcavation, the digital images were used as registration tool. Our results suggest...

Effects of OK-432 (picibanil) on the estrogen receptors of MCF-7 cells and potentiation of antiproliferative effects of tamoxifen in combination with OK-432.

Science.gov (United States)

Aoyagi, H; Iino, Y; Takeo, T; Horii, Y; Morishita, Y; Horiuchi, R

1997-01-01

OK-432 (picibanil), a streptococcal preparation, has a strong biological response modifier (BRM) function and is expected to produce clinical improvement and prolongation of survival in treated cancer patients in Japan. We were interested in whether OK-432 augments estrogen receptor (ER) levels in breast cancer. To investigate the effect of the BRMs on cellular growth and the characteristics of ER and progesterone receptors (PgR) in the human breast cancer cell line MCF-7, we used OK-432, Krestin (PSK), a protein-bound polysaccharide extracted from Coriolus versicolor, and lentinan, a fungal branched (1...3)-beta-D-glycan. OK432 and PSK dose dependently inhibited DNA synthesis of MCF-7 cells, and the 50% inhibitory concentrations of OK-432 and PSK were 1.2 KE (klinische Einheit, clinical unit)/ml and 200 micrograms/ml, respectively. Lentinan showed no direct anticancer effect in vitro. We found that OK-432 induced a 2-fold increase in ER levels in MCF-7 cells at 0.005 KE/ml, but not in PgR. Lentinan and low-dose PSK did not change ER or PgR levels, but high-dose PSK decreased ER and PgR. We also studied the combined effect of OK-432 and antiestrogens, tamoxifen (TAM) and DP-TAT-59. The combined treatment with OK-432 and TAM showed an additive inhibitory effect on MCF-7 cells. These results suggest that OK-432 may augment the therapeutic effect of TAM in breast cancer.

OK-432 sclerotherapy for malleolar bursitis of the ankle.

Science.gov (United States)

Park, Kwang Hwan; Lee, Jongseok; Choi, Woo Jin; Lee, Jin Woo

2013-10-01

The purpose of this study was to evaluate the clinical outcomes and usefulness of OK-432 (Picibanil) sclerotherapy as a new option in the conservative treatment of patients with malleolar bursitis of the ankle. Retrospectively, we reviewed a total of 20 consecutive patients (20 feet) in whom OK-432 sclerotherapy had been performed between March 2009 and June 2010. After aspiration of fluid in the malleolar bursal sac, 0.05 mg of OK-432 was injected into the malleolar bursal sac. We evaluated the clinical outcomes and side effects at the following time points: 2 weeks, 1 month, 3 months, 6 months, and 1 year after OK-432 sclerotherapy. The responses to the treatment were assessed according to the degree of fluctuation, shrinkage of the bursal sac, and soft tissue swelling. Complete resolution was observed in 19 patients (95%) after the first or second application of OK-432 sclerotherapy, and a partial response was observed in 1 patient (5%) after a second application of OK-432 sclerotherapy. The physical component scores of SF-36 improved from 70.0 ± 6.8 to 76.5 ± 7.3 at the last follow-up (P = .0002). OK-432 sclerotherapy was a useful procedure for patients not responding to the usual conservative treatment of malleolar bursitis of the ankle. Level IV, retrospective case series.

Labeled OK-432, immunomodulator of streptococcus preparation, in cancer patients

International Nuclear Information System (INIS)

Toki, Hironobu; Ishikawa, Morihiro; Fujii, Masashi; Yumoto, Yasuhiro; Ishimitsu, Tetsusaburo

1982-01-01

We investigated the pharmacokinetics of OK-432, an immunomodulator of streptococcus preparation which, is used in cancer patients for active nonspecific immunotherapy. First, OK-432 was labeled with sup(99m)Technetium in vitro. Four patients with malignancy were studied. By the method of scintigraphy using gamma camera, OK-432 administered intravenously was found to be distributed in the liver, lung and spleen, by the decreasing grade. When OK-432 was administered subcutaneously or intramuscularly in the buttocks, most of the radioactivity of sup(99m)Technetium remained locally at the injected site. These results suggested that OK-432 given intravenously was effectively phagocytized by cells of reticuloendothelial system (RES). Compared with other routes of administration, the intravenous route of OK-432 administration is thus considered more effective in order to stimulate RES, which is responsible for the first step of immune reaction. (author)

Protective action of OK-432 (Picibanil) on the radiation-induced myelosuppression

International Nuclear Information System (INIS)

Aoki, Yoshiro

1986-01-01

This report aims to examine the alleviating action of OK-432 against the radiation-induced myelosuppression in the whole body irradiated mice. The mice treated with OK-432 were given OK-432 with the dose of 5.0 KE by intraperitoneal injection 24 hours before irradiation, while the control group was given 1.0 ml of saline according to the same procedure as the OK-432 group. The fifty percent lethal dose on the 30th day after the whole body irradiation is 700R in the OK-432 group, while it is 580R in the control group. The dose reduction factor (DRF) is 1.21 in this series. The white blood cell counts decreased after irradiation with 300R in both groups. The recovery of WBC counts in the OK-432 group began at the 6th or 7th day after irradiation, while the decreased level continued until the 20th day in the control group. The WBC counts and the spleen weights were examined on the 10th day after irradiation. The WBC counts of the OK-432 group were higher than those of the control group, the difference of which was statistically significant at the 5 % level at 300R. The spleens of the OK-432 group were heavier and larger than those of the control group, the difference of which was statistically significant at the 0.1 % level for the dose range from 300 to 500R. The HE-stained spleen of the OK-432 group on the 10th day after irradiation showed the increase of hematopoietic cells in the enlarged sinus in comparison with that of the control group. The timing of OK-432 administration and the percentage of the survival of the OK-432 group on 30th day, irradiated with 600R to the whole body, were examined. The 5.0 KE of OK-432 was injected from 4 days before and upto 4 days after irradiation to each group. When OK-432 was inected from 2 days before and upto 12 hours after irradiation, the OK-432 group showed the good survival rate in comparison with the control group. (J.P.N.)

Lipid corralling and poloxamer squeeze-out in membranes

DEFF Research Database (Denmark)

Wu, G.H.; Majewski, J.; Ege, C.

2004-01-01

Using x-ray scattering measurements we have quantitatively determined the effect of poloxamer 188 (P188), a polymer known to seal damaged membranes, on the structure of lipid monolayers. P188 selectively inserts into low lipid-density regions of the membrane and "corrals" lipid molecules to pack...... tightly, leading to unexpected Bragg peaks at low nominal lipid density and inducing lipid/poloxamer phase separation. At tighter lipid packing, the once inserted P188 is squeezed out, allowing the poloxamer to gracefully exit when the membrane integrity is restored....

Radiotherapy of medulloblastoma combined with OK-432 (Picibanil)

International Nuclear Information System (INIS)

Aoki, Yoshiro

1986-01-01

The OK-432 group consists of 8 Medulloblastoma patients, 5 Pinealoma patients and 1 Pons glioma patient, while the historical control group consists of 12 Medulloblastoma patients who have been treated only with radiation at NIRS. The frequency of the week when the value of white blood cell counts decreased below 2,500 was 13 weeks per 98 weeks of total observation period (13.3 %) in the OK-432 group. However, it was 37 weeks per 103 weeks (35.9 %) in the control group. The frequency of the week when the value of the platelet counts decreased below 10 x 10 4 was 5 weeks per 98 weeks (5.1 %) in the OK-432 group, while it was 21 weeks per 103 weeks (20.4 %) in the control group. The OK-432 group received 54.4 ± 3.3 Gy/ 34 ± 2 fractions/ 51 ± 4 days to the cerebellar tumor, except a one-year-old girl who received only a half of the radiation dose as the other patients who were older than 5 years, while the control group received 47.2 ± 7.3 Gy/ 34 ± 7 fractions/ 49 ± 10 days. In terms of TDF, the OK-432 group received 83.5 ± 8.7 and the control group received 63.5 ± 10.2, whereby the difference between the OK-432 group and the control group is statistically significant at 2 % level. To the spinal cord, the OK-432 group received 27.1 ± 3.1 Gy/ 27 ± 5 fractions/ 41 ± 9 days, while the control group received 25.4 ± 7.5 Gy/ 27 ± 13 fractions/ 43 ± 25 days. The survival rate of 8 Medulloblastoma patients treated with radiation combined with OK-432 is as follows : the relative survival rate is 75.1 % in one year, 62.5 % in 3 years and 62.5 % in 5 years, in contrast to the rate of 73.3 % in one year, 20.0 % in 3 years and 20.0 % in 5 years in the control group. (J.P.N.)

Generation of ecosystem hotspots using short-term cattle corrals in an African savanna

Science.gov (United States)

Many rangelands are now being managed for multiple uses, and it is increasingly important to identify livestock management practices that maximize long-term productivity, biodiversity and wildlife conservation. In sub-Saharan Africa, pastoralists and ranchers use temporary thorn-fence corrals (“boma...

Adult cystic hygroma: successful use of OK-432 (Picibanil).

Science.gov (United States)

Woolley, S L; Smith, D R K; Quine, S

2008-11-01

We report an adult case of cystic lymphangioma treated with OK-432 (Picibanil). A case report and review of the literature concerning the use of OK-432 to treat cystic lymphangioma is presented. A 31-year-old woman developed a cystic lymphangioma four weeks post-partum. This was treated initially by aspiration, for diagnostic purposes. Investigation suggested that surgery would be challenging. A review of the literature demonstrated success with OK-432 in the treatment of this condition, although primarily in the paediatric population. This patient was successfully treated thus, and at the time of writing remained symptom free. A suggested management plan is outlined. Treatment with OK-432 is useful in the management of cystic lymphangiomas in adults and should be considered as first line treatment.

OK-432 (Picibanil) therapy for lymphangiomas in children.

Science.gov (United States)

Laranne, J; Keski-Nisula, L; Rautio, Riitta; Rautiainen, Markus; Airaksinen, Mari

2002-05-01

Lymphangiomas are benign, soft tumors that most often affect the head and neck area, usually causing marked cosmetic and functional problems. Treatment options include surgery and a large number of different sclerotherapy agents. Surgical treatment is challenging because of the need for complete excision. The risk of damage to surrounding structures or poor cosmetic results is high. Various sclerotherapy agents have been shown to have minimal effects on lymphangiomas. Their use has been associated with severe systemic, local and cosmetic side effects. OK-432 (Picibanil) is a new and promising form of sclerotherapy. An intracystic injection of OK-432 produces a local inflammatory reaction, which leads to resolution of the lesion. We have treated 11 pediatric lymphangioma patients with OK-432 with excellent results: complete regression in six, marked regression in four and no response in one case. Local swelling should be anticipated, especially when treating lesions near the upper airway. We found OK-432 injections to be safe and effective as a first line of treatment for lymphangiomas.

The effect of OK-432 (Picibanil) injection on the histopathology of nasal turbinate.

Science.gov (United States)

Sengul, S; Kaygusuz, I; Akin, M M; Yalcin, Ş; Karlidag, T; Keles, E; Arslan, I

2015-12-01

This study aimed to assess the histopathological effect of OK-432 (Picibanil) on rabbit nasal turbinates. A total of 21 rabbits were divided into 3 treatment groups and various parts of both nasal turbinates were injected with 0.5 ml OK-432, 0.2 ml OK-432 or 0.6 ml saline (control). Bilateral nasal turbinates were later excised and studied under light microscopy to assess any histopathological changes. Animals in the 0.2 ml and 0.5 ml OK-432 groups exhibited mild ciliary loss, goblet cell loss and epithelial damage, and a marked increase in inflammatory cell infiltration, submucosal vascularisation and fibrosis. There was a significant difference in histopathological changes between the two OK-432 treated groups. In addition, each OK-432 treated group had significantly more inflammatory cell infiltration, increased submucosal vascularisation and fibrosis compared with controls. The marked fibrosis observed in OK-432-injected turbinates may be responsible for a reduction in turbinate size.

Prevention of radiation-induced bacteraemia by post-treatment with OK-432 and aztreonam

Energy Technology Data Exchange (ETDEWEB)

Kurishita, A.; Ono, T. (Tohoku Univ., Sendai (Japan). School of Medicine); Uchida, A. (Kyoto Univ. (Japan). Radiation Biology Center)

1993-03-01

The effects of combined treatment with OK-432, an immunomodulator prepared from Streptococcus haemolyticus, and aztreonam, a monobactum antibiotic, in the prevention of radiation-induced bacteraemia and mortality were examined in ICR-MCH mice irradiated with 9.5 Gy. The organisms recovered from the irradiated mice were Streptococcus faecalis and Proteus mirabilis. Treatment with aztreonam reduced the incidence of mice infected with Proteus mirabilis (p<0.01), but it showed no efficacy on Streptococcus faecalis. OK-432 could reduce the frequency of bacteraemia attributed to both organisms (p<0.05). Combined treatment with OK-432 and aztreonam further decreased the incidence of bacteraemia by both organisms; no organisms were recovered at 14 days following irradiation. The survival rate at 30 days following irradiation was 80% in mice treated with OK-432 plus aztreonam and 55% with OK-432 alone, while it was 0% in the groups treated with aztreonam or saline alone. These results indicated that combined treatment with OK-432 and a suitable antibiotic such as aztreonam is more effective than OK-432 or aztreonam alone. (Author).

Prevention of radiation-induced bacteraemia by post-treatment with OK-432 and aztreonam

International Nuclear Information System (INIS)

Kurishita, A.; Ono, T.; Uchida, A.

1993-01-01

The effects of combined treatment with OK-432, an immunomodulator prepared from Streptococcus haemolyticus, and aztreonam, a monobactum antibiotic, in the prevention of radiation-induced bacteraemia and mortality were examined in ICR-MCH mice irradiated with 9.5 Gy. The organisms recovered from the irradiated mice were Streptococcus faecalis and Proteus mirabilis. Treatment with aztreonam reduced the incidence of mice infected with Proteus mirabilis (p<0.01), but it showed no efficacy on Streptococcus faecalis. OK-432 could reduce the frequency of bacteraemia attributed to both organisms (p<0.05). Combined treatment with OK-432 and aztreonam further decreased the incidence of bacteraemia by both organisms; no organisms were recovered at 14 days following irradiation. The survival rate at 30 days following irradiation was 80% in mice treated with OK-432 plus aztreonam and 55% with OK-432 alone, while it was 0% in the groups treated with aztreonam or saline alone. These results indicated that combined treatment with OK-432 and a suitable antibiotic such as aztreonam is more effective than OK-432 or aztreonam alone. (Author)

Actions for the environmental adequateness and emissions control at the Martin del Corral power plant-Termozipa; Obras de adecuacion ambiental y control de emisiones para la central termoelectrica Martin del Corral - Termozipa

Energy Technology Data Exchange (ETDEWEB)

Arevalo Osorio, Luis [Empresa de Energia de Bogota, Bogota (Colombia)

1997-12-31

In this paper the general data on the Martin del Corral-Termozipa, of Colombia, fossil fueled power plant are exposed. The results of a study to determine the environmental impact originated in the influence zone of this Power Plant are presented, particularly on the Bogota River. The study was framed into the environmental policy driven by the Colombian sector. Different solutions addressed to the optimization of the handling, capacity and control of the emissions and counteract the pollution possibilities of the Bogota River are described [Espanol] En esta ponencia se exponen datos generales de la central termoelectrica Martin del Corral - Termozipa-, de Colombia. Se presentan los resultados de un estudio para determinar el impacto ambiental ocasionado en la zona de influencia de esta central, y en particular sobre el rio Bogota. El estudio se enmarco dentro de la politica ambiental impulsada por el sector colombiano. Se describen diversas soluciones encaminadas a optimizar el manejo, capacidad y control de las emisiones y contrarrestar las posibilidades de contaminacion del rio Bogota

Actions for the environmental adequateness and emissions control at the Martin del Corral power plant-Termozipa; Obras de adecuacion ambiental y control de emisiones para la central termoelectrica Martin del Corral - Termozipa

Energy Technology Data Exchange (ETDEWEB)

Arevalo Osorio, Luis [Empresa de Energia de Bogota, Bogota (Colombia)

1996-12-31

In this paper the general data on the Martin del Corral-Termozipa, of Colombia, fossil fueled power plant are exposed. The results of a study to determine the environmental impact originated in the influence zone of this Power Plant are presented, particularly on the Bogota River. The study was framed into the environmental policy driven by the Colombian sector. Different solutions addressed to the optimization of the handling, capacity and control of the emissions and counteract the pollution possibilities of the Bogota River are described [Espanol] En esta ponencia se exponen datos generales de la central termoelectrica Martin del Corral - Termozipa-, de Colombia. Se presentan los resultados de un estudio para determinar el impacto ambiental ocasionado en la zona de influencia de esta central, y en particular sobre el rio Bogota. El estudio se enmarco dentro de la politica ambiental impulsada por el sector colombiano. Se describen diversas soluciones encaminadas a optimizar el manejo, capacidad y control de las emisiones y contrarrestar las posibilidades de contaminacion del rio Bogota

Prevalencia y factores asociados a ruptura prematura de membranas en gestantes del Hospital Vicente Corral Moscoso, Cuenca-Ecuador, noviembre 2011-noviembre 2012

OpenAIRE

Cuenca Condoy, Elsa María

2013-01-01

Objetivo: Determinar la prevalencia de ruptura prematura de membranas y factores asociados en gestantes del Hospital Vicente Corral Moscoso. Cuenca-Ecuador, durante el periodo enero a julio 2012. -Método y técnicas: Estudio transversal de prevalencia, en 657 gestantes que acudieron al Hospital Vicente Corral Moscoso. - Hipótesis: La Ruptura prematura de membranas es más frecuente cuando se asocian factores como antecedente de infección del tracto urinario, bacteriuria, amenaza de parto pretér...

The transcriptome of the Didelphis virginiana opossum kidney OK proximal tubule cell line.

Science.gov (United States)

Eshbach, Megan L; Sethi, Rahil; Avula, Raghunandan; Lamb, Janette; Hollingshead, Deborah J; Finegold, David N; Locker, Joseph D; Chandran, Uma R; Weisz, Ora A

2017-09-01

The OK cell line derived from the kidney of a female opossum Didelphis virginiana has proven to be a useful model in which to investigate the unique regulation of ion transport and membrane trafficking mechanisms in the proximal tubule (PT). Sequence data and comparison of the transcriptome of this cell line to eutherian mammal PTs would further broaden the utility of this culture model. However, the genomic sequence for D. virginiana is not available and although a draft genome sequence for the opossum Monodelphis domestica (sequenced in 2012 by the Broad Institute) exists, transcripts sequenced from both species show significant divergence. The M. domestica sequence is not highly annotated, and the majority of transcripts are predicted rather than experimentally validated. Using deep RNA sequencing of the D. virginiana OK cell line, we characterized its transcriptome via de novo transcriptome assembly and alignment to the M. domestica genome. The quality of the de novo assembled transcriptome was assessed by the extent of homology to sequences in nucleotide and protein databases. Gene expression levels in the OK cell line, from both the de novo transcriptome and genes aligned to the M. domestica genome, were compared with publicly available rat kidney nephron segment expression data. Our studies demonstrate the expression in OK cells of numerous PT-specific ion transporters and other key proteins relevant for rodent and human PT function. Additionally, the sequence and expression data reported here provide an important resource for genetic manipulation and other studies on PT cell function using these cells. Copyright © 2017 the American Physiological Society.

Manejo del trauma de tórax y características demográficas, hospital Vicente Corral Moscoso. Cuenca – Ecuador.

OpenAIRE

Guachún Guachún, Mayra Alejandra; Aguirre Vintimilla, Marcos Andrés; Lituma Yascaribay, Sara Cumandá; Tapia Gudiño, Johnny Amilcar

2016-01-01

Objetivo: Analizar el manejo del trauma de tórax en el Hospital Vicente Corral Moscoso y describir las características demográficas de la población estudiada. Método: Estudio descriptivo retrospectivo, la muestra fue de 167 pacientes atendidos en el servicio de Emergencia del Hospital Vicente Corral Moscoso, con diagnóstico de trauma de tórax, durante el periodo enero de 2013 a junio de 2015; los datos se obtuvieron de las historias clínicas. Se analizaron las variables de datos demográ...

Biological effect of OK-432 (picibanil) and possible application to dendritic cell therapy.

Science.gov (United States)

Ryoma, Yoshiki; Moriya, Yoichiro; Okamoto, Masato; Kanaya, Isao; Saito, Motoo; Sato, Mitsunobu

2004-01-01

OK-432 (Picibanil), a streptococcal preparation with potent biological response modifying activities, was approved in Japan as an anticancer agent in 1975. In the ensuing 30 years, since then, a significant amount of data, including clinical as well as experimental studies, has been accumulated. OK-432 has been reported to induce various cytokines, activate immunological cells and thus augment anticancer immunity. Recently, the interrelation between innate immunity and adaptive immunity has become clear and it was reported that OK-432 acts, at least in part, via Toll-like receptor (TLR) 4-MD2 signaling pathway. In addition, dendritic cells (DCs) are considered to play a pivotal role in immunological response and it is reported that OK-432 induced maturation of DCs both in vitro and in vivo. These results suggest that OK-432 is a useful adjuvant in DC-based anticancer immunotherapy. Clinical studies of DC therapy with OK-432 are under way.

The prognostic advantage of preoperative intratumoral injection of OK-432 for gastric cancer patients

Science.gov (United States)

Gochi, A; Orita, K; Fuchimoto, S; Tanaka, N; Ogawa, N

2001-01-01

To investigate, by a multi-institutional randomized trial, the prognostic significance of the augmentation of tumour-infiltrating lymphocytes (TILs) by preoperative intratumoral injection of OK-432 (OK-432 it), a bacterial biological response modifier, in patients with gastric cancer. The 10-year survival and disease-free survival were examined and analysis of the factors showing survival benefit was performed. 370 patients who had undergone curative resection of gastric cancer were enrolled in this study and followed up for 10 years postoperatively. Patients were randomized into either an OK-432 it group or a control group. Ten Klinishe Einheit (KE) of OK-432 was endoscopically injected at 1 to 2 weeks before the operation in the OK-432 it group. Both groups received the same adjuvant chemoimmunotherapy consisting of a bolus injection of mitomycin C (0.4 mg kg−1i.v.) and administration of tegafur and OK-432 from postoperative day 14 up to 1 year later. Tegafur (600 mg day−1) was given orally and OK-432 (5 KE/2 weeks) was injected intradermally for a maintenance therapy. The TILs grades in resected tumour specimens and presence of metastasis and metastatic pattern in dissected lymph nodes were examined. Multivariate analysis was performed to determine the efficacy of OK-432 it on prognostic factors. All patients were followed up for 10 years. The overall 5- and 10-year survival rates and disease-free survival rates of the OK-432 it group were not significantly higher than those of the control group. However, OK-432 it significantly increased the 5- and 10-year survival rates of patients with stage IIIA + IIIB, moderate lymph node metastasis (pN2), and positive TILs. OK-432 it was most effective at prolonging the survival of patients who had both positive TILs and lymph node metastasis. The OK-432 it group with positive TILs showed a significant decrease in metastatic lymph node frequency and in the number of lymph node micro- metastatic foci when compared to

Successful pleurodesis with OK-432 (picibanil in preterm infants with persistent pleural effusion

Directory of Open Access Journals (Sweden)

Jeong Eun Kim

2012-05-01

Full Text Available OK-432 (picibanil is an inactivated preparation of &lt;em&gt;Streptococcus pyogenes&lt;/em&gt; that causes pleurodesis by inducing a strong inflammatory response. Intrapleural instillation of OK-432 has recently been used to successfully treat neonatal and fetal chylothorax. Here we report a trial of intrapleural instillation of OK-432 in two preterm infants who were born with hydrops fetalis and massive bilateral pleural effusion. Both cases showed persistent pleural effusion, refractory to conservative treatment, up to postnatal days 26 and 46, respectively. An average of 80 to 140 mL of pleural fluid was drained daily. In case 1, the infant was treated with OK-432 during the fetal period at gestation 28 weeks and 4 days of gestation, but showed recurrence of pleural effusion and progressed into hydrops. Within two to three days after OK-432 injection, the amount of pleural fluid drainage was dramatically decreased and there was no reaccumulation. We did not observe any side effects related to OK-432 injection. We suggest that OK-432 should be considered as a therapeutic option in infants who have persistent pleural effusion for more than four weeks, with the expectation of the early removal of the chest tube and a good outcome.

OK-432 as a sclerosing agent to treat wound-healing impairment.

Science.gov (United States)

Fasching, G; Sinzig, M

2007-12-01

We report on the application of OK-432 (picibanil) in a patient with prolonged wound healing impairment. A 13-year-old girl had suffered a polytrauma with a displaced fracture of the sacrum which required neurosurgical decompression of the sacral plexus. Postoperatively, a seroma with recurrent fistulation was seen. Excision of the wound, prolonged suction drainage and the instillation of hypertonic glucose solution did not have any effect over a period of four months postoperatively. Relying on our personal experience of the treatment of lymphangiomas using OK-432 we instilled OK-432 into the wound. Leakage stopped immediately, there was a regression of fluid accumulation and four weeks later the ultrasound examination was normal. The patient is still asymptomatic four years after treatment. OK-432 can be used effectively for the treatment of chronic wound healing impairment.

Trauma, diez años de experiencia, Hospital Vicente Corral Moscoso

OpenAIRE

Astudillo Molina, Rubén Arturo; Salamea Molina, Juan Carlos; Crespo Riquetti, Paola Marcela; Salamea Molina, Pablo Javier

2010-01-01

Objetivo Realizar una descripción demográfica, forma y estado de llegada, etiología, tipo de trauma y hallazgos, en pacientes intervenidos quirúrgicamente y dados de alta del servicio de Cirugía General del Hospital Vicente Corral Moscoso, Cuenca – Ecuador. Pacientes y métodos. Es un estudio descriptivo, realizado en un periodo de 10 años, 1995 al 2005; se revisó el libro de altas hospitalarias, identificando 1415 historias clínicas. Registrando: año, sexo, edad, procedencia, signos ...

Whole abdominal irradiation for ovarian cancer in combined treatment with OK-432 picibanil

International Nuclear Information System (INIS)

Morita, Shinroku; Arai, Tatsuo; Tsunemoto, Hiroshi

1986-01-01

One hundred seventeen patients with postoperative ovarian cancer who were treated with whole abdominal irradiation by the open-field technique were analyzed as to the effectiveness of combined therapy with or without OK-432. OK-432, 0.2 to 2.0 (KE) (kev) daily, has been used to prevent bone marrow suppression since 1978 at NIRS. Cumulative five-year survival rates were 63.6 % in the OK-432 group (37 patients) and 54.5 % in the NON-OK-432 group (34 patients). The complete rates of previously arranged treatment schedules were 81 % and 66 % in the two groups, respectively, as we originally intended. (author)

[Treatment of lymphangioma with OK-432 infiltration].

Science.gov (United States)

Rodríguez, J; Cáceres, F; Vargas, P

2012-10-01

The management of lymphangioma using sclerotherapy has proven to be an effective therapeutic. Our aim was to evaluate the therapeutic efficacy of OK-432 (Picibanil) in patients with lymphagioma. The study was performed from November 2010 to July 2011. Fifteen patients of both genders were diagnosed with lymphangioma, 12 days to 12 years old. All patients were infiltrated with OK-432. The studied variables were: previous surgery, localization, type of lymphangioma, number of effective injections, reduction of mass valued as excellent (100% reduction), good (reduction > 50%) and bad (reduction < 50%), presence of recurrence and complications. 40% of pacients had prior surgery and 53.3% were located in the cervical-face region. The type of macrocystic lymphangioma was present in 40% of the series, mixed type in 46.6% and microcystic type in 13.4%. The number of effective infiltrations were 3. In 6 cases (40%) the result was excellent in 5 cases (33.4%) the result was good and in 4 cases (26.6%). We had 1 recurrence (6.6%) and we haven't had complications. Injection of OK-432 in macrocystic lymphangioma and mixed had a safe therapeutic modality with satisfactory results. So it is a valid alternative to conventional surgery.

Inhibitory effects of OK-432 (Picibanil) on cellular proliferation and adhesive capacity of breast carcinoma cells.

Science.gov (United States)

Horii, Yoshio; Iino, Yuichi; Maemura, Michio; Horiguchi, Jun; Morishita, Yasuo

2005-02-01

We investigated the potent inhibitory effects of OK-432 (Picibanil) on both cellular adhesion and cell proliferation of estrogen-dependent (MCF-7) or estrogen-independent (MDA-MB-231) breast carcinoma cells. Cellular proliferation of both MCF-7 and MDA-MB-231 cells was markedly inhibited in a dose-dependent manner, when the carcinoma cells were exposed to OK-432. Cell attachment assay demonstrated that incubation with OK-432 for 24 h reduced integrin-mediated cellular adhesion of both cell types. However, fluorescence activated cell sorter (FACS) analysis revealed that incubation with OK-432 for 24 h did not decrease the cell surface expressions of any integrins. These results suggest that the binding avidity of integrins is reduced by OK-432 without alteration of the integrin expression. We conclude that OK-432 inhibits integrin-mediated cellular adhesion as well as cell proliferation of breast carcinoma cells regardless of estrogen-dependence, and that these actions of OK-432 contribute to prevention or inhibition of breast carcinoma invasion and metastasis.

Perfil de ácidos grasos en carne de toretes Europeo x Cebú finalizados en pastoreo y en corral

Directory of Open Access Journals (Sweden)

Maribel Montero-Lagunes

2011-01-01

Full Text Available El objetivo fue determinar el perfil de ácidos grasos en grasa intramuscular de toretes encastados de Europeo (Bos taurus con Cebú (Bos indicus, finalizados en pastoreo y en corral. Cincuenta y dos toretes se analizaron con un ANDEVA en un arreglo factorial 2 x 2. La mitad de los animales fueron finalizados en pastoreo , siendo el pasto estrella de África [Cynodon plectostachyus (K. Schum Pilg.] la base de la alimentación, y la otra mitad en corral alimentados con 65 % de maíz, 10 % de pasta de soya, 20 % de heno, 4 % de sebo, 1 % de urea y minerales. La mitad de cada grupo consistió de toretes con más de ¾ B. taurus, y la otra mitad mayormente ¾ B. indicus . Los toretes se sacrificaron con 500 kg de peso. Se tomaron muestras del músculo Longissimus dorsi de la región de la 12a costilla. Los lípidos se analizaron por cromatografía de gases. El ácido graso más abundante (mg/g de grasa fue el C18,1 (381±16.4 seguido por el C16,0 (250±5.3 y el C18,0 (201±8.6, El contenido de C18:2, 9-cis, 11-trans fue de 6.1±0.67. C14,0 y C16,0 fueron mayores en corral, y C18,0 fue más alto en pastoreo (P<0.01. C14,0, C16,0, C18,2, C18,3 y CLA total fueron mayores (P<0.05 en B. indicus y C18,0 fue más alto (P<0.05 en B. taurus. Se concluye que el perfil de ácidos grasos en toretes cruzados de Europeo por Cebú es diferente si es finalizado en pastoreo o en corral y por el nivel de encaste.

Application of geophysical methods to gold prospecting in Minas de Corrales, Uruguay

International Nuclear Information System (INIS)

Costa, Antonio Flavio U.; Dias, Rogerio Aguirre; Barcelos, Andre B.B. de

1993-01-01

Geophysical methods were tested in San Gregorio gold mine, Minas de Corrales, north region of Uruguay. The ores are mainly stockworks, sheeted veinlet zones, ore shoot and disseminated sulfides types, situated in a silicated and carbonated shear zone structure, over granitic mylonites, quartz diorites, quartz-feldspathic breccia, basic rocks and quartz veins. Magnetic and radiometric methods were applied . VLF and EM34-3 detected the high resistivity silicated and carbonated zone and IP detected a weak PFE anomaly associated with pyrite/gold zone. (author)

Balance control impairment induced after OKS in patients with vestibular migraine: an intercritical marker.

Science.gov (United States)

Panichi, R; Cipriani, L; Sarchielli, P; Di Mauro, M; Pettorossi, V E; Ricci, G; Faralli, M

2015-09-01

The aim of the study was to assess the effects of optokinetic stimulation (OKS) on vestibular postural control in migraine patients with recurrent vertigo. 15 patients with vestibular migraine (VM) were enrolled in a posturographic study in eyes open (OE) and eyes closed (CE) condition. The tests were performed between attacks of headache and vertigo at three different time: before, during, and 60 min after OKS. Data of patients with VM were compared with those obtained from two control groups matched for sex and age (15 for each group): (a) normal subjects not suffering from migraine without history of recurrent vertigo (N group); (b) subjects suffering from migraine with no history of recurrent vertigo (M group). Mean sway path velocity and sway area were analyzed. OKS increased the instability in all groups during the stimulus, and both the velocity and area values were higher in M and VM group. However, there was not significant difference between these two groups when stability was examined in OE condition before, during and after OKS stimulation. Conversely, in CE condition a significant greater instability was induced after OKS stimulation only in VM. In particular, post-stimulus values were significantly higher than the pre-stimulus one only in this group, while no significant difference was observed in other groups. A spatial analysis of the sway area evidenced that the instability induced by the OKS in VM group occurred along the direction of OKS. We suggest that this enhanced instability observed after OKS during the intercritical period may be considered an useful marker to support the diagnostic definition of VM in the absence of other vestibular signs.

Características de las infecciones nosocomiales en el servicio de cuidados intensivos pediátricos del Hospital Vicente Corral Moscoso, Cuenca 2014 -2015

OpenAIRE

Salcedo González, Rosa Karina

2016-01-01

Objetivo: Determinar las características de las infecciones nosocomiales en el servicio de Cuidados Intensivos Pediátricos del Hospital Vicente Corral Moscoso durante el año 2014 al 2015. Materiales y métodos: estudio descriptivo llevado a cabo en 32 pacientes diagnosticados de infección nosocomial en la Unidad de Cuidados Intensivos Pediátricos del Hospital Vicente Corral Moscoso; los datos fueron recogidos en un formulario; se tabularon en el programa SPSS versión 15 y para el análisis ...

Efficacy and safety of OK-432 immunotherapy of lymphatic malformations.

Science.gov (United States)

Smith, Mark C; Zimmerman, M Bridget; Burke, Diane K; Bauman, Nancy M; Sato, Yutaka; Smith, Richard J H

2009-01-01

To determine the efficacy and safety of the immunostimulant OK-432 (Picibanil) as a treatment option in the management of children with cervicofacial lymphatic malformations. A prospective, randomized, multi-institutional phase II clinical trial at 27 U.S. academic medical centers. 182 patients with lymphatic malformations (LM) were enrolled between January 1998 and November 2004. Of the 151 patients with complete case report forms, 117 patients were randomized into immediate or delayed treatment groups; 34 patients were nonrandomized and assigned to the open-label group. Treatment consisted of a four-dose intralesional injection series of OK-432 at eight-week intervals. Patients randomized into the delayed treatment group served as observational controls for spontaneous regression. Response to therapy was measured radiographically by quantitating change in lesion size and graded as complete (90%-100%), substantial (60%-89%), intermediate (20%-59%), or none (<20%). Of 117 patients randomized with intent-to-treat, 68% demonstrated a complete or substantial response to OK-432 immunotherapy. Response data for macrocystic LM were higher, with a complete or substantial response in 94% of patients; 63% of patients with mixed macrocystic-microcystic LM responded to treatment; no patients with microcystic LM responded to treatment. Spontaneous resolution occurred in less than 2% of patients. Median follow-up of 2.9 years demonstrated a 9% recurrence rate. Major adverse effects related to therapy occurred in 11 patients. As compared to historical surgical data on LM, OK-432 immunotherapy is more effective (P < .001) and has a lower morbidity (P < .001). OK-432 immunotherapy is an effective, safe, and simple treatment option for the management of macrocystic cervicofacial LM. ClinicalTrials.gov Identifier: NCT00010452.

OK-432 sclerotherapy of cervical chylous lymphocele after neck dissection.

Science.gov (United States)

Roh, Jong-Lyel; Park, Chan Il

2008-06-01

Postoperative cervical chylous lymphoceles are extremely rare circumscribed collections of lymph which are usually treated by drainage or surgical exploration, but rarely by sclerotherapy. We investigated the efficacy of OK-432 (Picibanil, Chungai Pharmaceutical Co., Tokyo, Japan) sclerotherapy in the treatment of cervical lymphocele after neck dissection. Four patients with postoperative lymphocele who could not be cured by repeated percutaneous needle aspiration and pressure dressing were treated with intralesional injection of 0.1-0.2 mg OK-432 after aspiration of fluid. The aspirated fluid was assessed biochemically and cytologically, and regular palpation and ultrasonography/computed tomography were used to evaluate outcomes and recurrences. Two patients with chyle leak during neck dissection had lymphoceles in the left supraclavicular region 3 weeks later. The other two patients had lymphoceles on the right neck 9 and 12 months, respectively, after neck dissection. All aspirated fluids were chylous in origin without tumor cells. OK-432 sclerotherapy scored all four lesions with no major complications except for fever and local pain for several days. No lymphocele recurrences or metastatic cancers were observed in any patient for >1 year after sclerotherapy. Intralesional injection of OK-432 may be a safe and effective alternative to surgical exploration in the treatment of cervical lymphocele after neck dissection.

Potential effects of surface coal mining on the hydrology of the Corral Creek area, Hanging Woman Creek coal field, southeastern Montana

Science.gov (United States)

McClymonds, N.E.

1984-01-01

The Corral Creek area of the Hanging Woman Creek coal field, 9 miles east of the Decker coal mines near the Tongue River, contains large reserves of Federal coal that have been identified for potential lease sale. A hydrologic study was conducted in the area to describe existing hydrologic systems and to study assess potential impacts of surface coal mining on local water resources. Hydrogeologic data collected indicate that aquifers are coal and sandstone beds within the Tongue River Member of the Fort Union Formation (Paleocene age) and sand and gravel in valley alluvium (Pleistocene and Holocene age). Surface-water resources are limited to a few spring-fed stock ponds in the higher parts of the area and the intermittent flow of Corral Creek near the mouth. Most of the stock ponds in the area become dry by midsummer. Mining of the Anderson coal bed would remove three stock wells and would lower the potentiometric surface within the coal and sandstone aquifers. The alluvial aquifer beneath Corral Creek and South Fork would be removed. Although mining would alter the existing hydrologic systems and remove several shallow wells, alternative ground-water supplies are available that could be developed to replace those lost by mining. (USGS)

Compost de ave de corral como componente de sustratos

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Lorena Alejandra Barbaro¹

2011-07-01

Full Text Available El sustrato para cultivo es un material que colocado en un contenedor permite el anclaje del sistema radicular, proporcionando agua y nutrientes. Entre los materiales empleados para formular sustratos se encuentran los compost. Entre ellos el compost de cama de ave de corral (CAC, elaborado en base al estiércol de aves mezclado con los materiales que forman su lecho. El objetivo de este trabajo fue evaluar dos compost de CAC como componente de sustrato, mediante el desarrollo de plantas de Coral (Salvia splendens. Uno de los compost contenía cama de stud (CAC+S durante su compostaje. Se formularon sustratos con diferentes proporciones de compost de CAC, compost de corteza de pino y pinocha, luego fueron analizados física y químicamente. A las plantas cultivadas en cada sustrato se midió la longitud y el diámetro del tallo, peso fresco y seco de la parte aérea y radicular. La densidad, porosidad y capacidad de retención de agua de todos los sustratos fueron aceptables. El pH de ambos compost de CAC fue mayor a 6,3, y los valores de las mezclas se encontraron dentro del rango aceptable. Todos los sustratos superaron 1 dS m-1 (1+5 v/v, principalmente los formulados con compost de CAC+S, cuyo material puro contenía altos niveles salinos. Al disminuir el porcentaje de CAC en las mezclas, diminuyó la concentración de cada nutriente. Las plantas cultivadas en el sustrato comercial y en las mezclas con 20% de CAC fueron las que lograron los mayores pesos aéreos y radiculares, diámetro y longitud del tallo. Por lo tanto, el compost de ave de corral podría ser una alternativa viable como componente de sustrato si se lo utiliza hasta un 20%.

OK-Net Arable online knowledge platform

DEFF Research Database (Denmark)

Rasmussen, Ilse Ankjær; Jensen, Allan Leck; Jørgensen, Margit Styrbæk

2017-01-01

The complexity of organic farming requires farmers to have a very high level of knowledge and skills, but exchange on organic farming techniques remains limited. In order to increase productivity and quality in organic arable cropping in Europe, the thematic network OK-Net Arable under Horizon 20...

Combination therapy with radiation and OK-432 immunotherapy of cancer patients

International Nuclear Information System (INIS)

Hashimoto, Shozo; Miyamoto, Hiroshi

1978-01-01

We treated cancer patients with radiotherapy alone and with radiation plus immunotherapy at the Department of Radiology, Keio University Hospital. In all of the cancer patients who had radiationtherapy alone, a general depression in their immune reactivity was seen, but not seen in those who received radiationtherapy plus immunotherapy. Immunotherapy is defined as a stimulator of cancer patient's immune reaction. Usually radiationtherapy caused lymphopenia in which mainly T lymphocytes were decreased in number selectively, but there was no lymphopenia in cases treated with immunotherapy. We have performed nonspecific immunotherapy with OK-432. The result indicated that T lymphocytes were increased by OK-432 in spite of radiationtherapy. From this fact, OK-432 will be useful for suppression of metastasis and regression of tumors. (auth.)

Alleviating action of OK-432 (Picibanil) on the myelosuppression in medulloblastoma patients induced by whole axis irradiation

International Nuclear Information System (INIS)

Aoki, Yoshiro

1982-01-01

The test subjects termed as OK-432 group which consist of 4 patients of Medulloblastoma and 2 of Pinealoma, underwent the whole axis irradiation in combination with OK-432. The control group consisting of 9 Medulloblastoma patients was subjected to the same radiation treatment without OK-432. Six of the nine patients (66.7%) irradiated showed the decrease of peripheral white blood cell counts down to 2,500, whereas, only two of six patients showed a similar decrement in OK-432 group. Three of the nine patients (33.3%) in the control group showed the decrease of white blood cell down to 2,000, but only one of the six patients in OK-432 group. The neutrophil counts decreased below the level of 1,000 in three of the nine patients (33.3%) in the control group, but none in the OK-432 group. The platelet counts decreased below the level of 100,000 in five of the nine patients (55.6%) in the control group during the irradiation period, but only one patient in the OK-432 group showed a decrease down to 100,000 counts. Three of the nine patients (33.3%) in the control group had to be stopped irradiation due to the severe leukopenia and thrombocytopenia, in contrast to the OK-432 group, which completed whole axis irradiation without interruption. These results seem to indicate that OK-432 alleviated the myelosuppression induced in patients by whole axis irradiation. This alleviating action of OK-432 is considered to be applicable to the treatment of Medulloblastoma patients. (J.P.N.)

Alleviating action of OK-432 (Picibanil) on the myelosuppression in Medulloblastoma patients induced by whole axis irradiation

Energy Technology Data Exchange (ETDEWEB)

Aoki, Yoshiro (National Inst. of Radiological Sciences, Chiba (Japan))

1982-11-01

The test subjects termed as OK-432 group which consist of 4 patients of Medulloblastoma and 2 of Pinealoma, underwent the whole axis irradiation in combination with OK-432. The control group consisting of 9 Medulloblastoma patients was subjected to the same radiation treatment without OK-432. Six of the nine patients (66.7%) irradiated showed the decrease of peripheral white blood cell counts down to 2,500, whereas, only two of six patients showed a similar decrement in OK-432 group. Three of the nine patients (33.3%) in the control group showed the decrease of white blood cell down to 2,000, but only one of the six patients in OK-432 group. The neutrophil counts decreased below the level of 1,000 in three of the nine patients (33.3%) in the control group, but none in the OK-432 group. The platelet counts decreased below the level of 100,000 in five of the nine patients (55.6%) in the control group during the irradiation period, but only one patient in the OK-432 group showed a decrease down to 100,000 counts. Three of the nine patients (33.3%) in the control group had to be stopped irradiation due to the severe leukopenia and thrombocytopenia, in contrast to the OK-432 group, which completed whole axis irradiation without interruption. These results seem to indicate that OK-432 alleviated the myelosuppression induced in patients by whole axis irradiation. This alleviating action of OK-432 is considered to be applicable to the treatment of Medulloblastoma patients.

The therapeutic effect of OK-432 (picibanil) sclerotherapy for benign neck cysts.

Science.gov (United States)

Kim, Myung Gu; Kim, Sun Gon; Lee, Jun Ho; Eun, Young Gyu; Yeo, Seung Geun

2008-12-01

In general, benign neck cysts are treated by surgical excision. This can present technical difficulties and frequent recurrences, because of insufficient surgery. Sclerosing agents such as OK-432 have been tested for the nonsurgical treatment of these cysts. We have assessed the efficacy of OK-432 sclerotherapy for benign neck cysts. The study group consisted of 75 patients (42 men, 33 women) diagnosed with and treated for benign neck cysts between March 2001 and December 2007 by intralesional injection of OK-432. The liquid content of each cyst was aspirated as much as possible, and the same volume of OK-432 solution was injected. Patients were assessed by ultrasonography or computerized tomography, and therapeutic outcomes and adverse effects were evaluated by patient age, sex, cyst type, and number of injections. Of the 75 treated patients, 31 (41.3%) showed total shrinkage, seven (9.3%) showed near-total shrinkage (>90% of cyst volume), five (6.6%) showed marked shrinkage (>70% of cyst volume), and 17 (22.7%) showed partial shrinkage (<70% of cyst volume). No response was seen in 15 patients (20%). Despite repeated sclerotherapy, eight patients (10.7%) showed recurrences. Minor adverse effects of therapy included fever, localized pain, and odynophagia but these complications spontaneously disappeared within several days. OK-432 sclerotherapy is a safe and effective primary alternative to surgery in patients with benign neck cysts.

OK-432 sclerotherapy for benign cystic head and neck lesions

International Nuclear Information System (INIS)

Kim, Chang Hyun; Rho, Myung Ho; Lee, Sang Wook

2003-01-01

To evaluate the efficacy of OK-432 solution for slerotheraphy of cystic lesions of the head and neck. Nineteen cystic lesions comprising ten plunging ranulas, three simple ranulas, three cystic lymphangiomas, one first branchial cleft cyst and two unknown supraclavicular cysts considered to be lymphangiomas were treated by sucking out as much liquid content as possible and then injecting the same volume of OK-432 solution under ultrasound guidance. Patients were followed up clinically and radiologically. Follow-up sonography or CT- performed after a mean interval of nine months showed total or near-total shrinkage of four plunging ranulas. However, six such lesions recurred in spite of more than one (mean, two) sclerotherapy sessions. In cases involving two simple ranulas at the floor of the mouth, failure resulted from extracystic leakage of OK-432 solution via the puncture site. Two unilocular cystic lymphangiomas completely regressed during the follow-up period (mean, seven months), but the multiocular type showed a 65% volume reduction after 12 months. A first branchial cleft cyst was markedly reduced in size, with only a small cystic portion remaining after eight months, follow-up. Two supraclavicular cysts with straw-color fluid did not respond to sclerotherapy. OK-432 sclerotherapy of macrocystic lymphangiomas is an effective and promising alternative to surgery. For other cysts, however, including plunging ranula, efficacy, varied, and 64% of such lesions recurred

OK-432 sclerotherapy for benign cystic head and neck lesions

Energy Technology Data Exchange (ETDEWEB)

Kim, Chang Hyun; Rho, Myung Ho; Lee, Sang Wook [Masan Samsung Hospital, Masan (Korea, Republic of)

2003-12-01

To evaluate the efficacy of OK-432 solution for slerotheraphy of cystic lesions of the head and neck. Nineteen cystic lesions comprising ten plunging ranulas, three simple ranulas, three cystic lymphangiomas, one first branchial cleft cyst and two unknown supraclavicular cysts considered to be lymphangiomas were treated by sucking out as much liquid content as possible and then injecting the same volume of OK-432 solution under ultrasound guidance. Patients were followed up clinically and radiologically. Follow-up sonography or CT- performed after a mean interval of nine months showed total or near-total shrinkage of four plunging ranulas. However, six such lesions recurred in spite of more than one (mean, two) sclerotherapy sessions. In cases involving two simple ranulas at the floor of the mouth, failure resulted from extracystic leakage of OK-432 solution via the puncture site. Two unilocular cystic lymphangiomas completely regressed during the follow-up period (mean, seven months), but the multiocular type showed a 65% volume reduction after 12 months. A first branchial cleft cyst was markedly reduced in size, with only a small cystic portion remaining after eight months, follow-up. Two supraclavicular cysts with straw-color fluid did not respond to sclerotherapy. OK-432 sclerotherapy of macrocystic lymphangiomas is an effective and promising alternative to surgery. For other cysts, however, including plunging ranula, efficacy, varied, and 64% of such lesions recurred.

[Unsuccessful treatment with OK-432 picibanil for orbital lymphangioma].

Science.gov (United States)

Lanuza García, A; Bañón Navarro, R; Llorca Cardeñosa, A; Delgado Navarro, C

2012-01-01

Lymphangioma is a malformation of the lymphatic system. The classic approach is surgery. We report a case of orbital lymphangioma in a girl who was given OK-432 to avoid surgery and its complications. OK-432 is a lyophilized mixture of group A Streptococcus pyogenes which produces a fibrosis limited to the lesion with a high cure rate. The main advantages are the easy intra-lesional application. with no scars and or damage of closed areas. Its main disadvantage is a significant local inflammatory reaction. Copyright © 2011 Sociedad Española de Oftalmología. Published by Elsevier Espana. All rights reserved.

77 FR 47657 - Wichita Mountains Wildlife Refuge, Comanche County, OK; Comprehensive Conservation Plan and...

Science.gov (United States)

2012-08-09

... for white-tailed deer opportunities through and feral hog hunts. and elk. signage, facilities, Manage... rock climbing, signage or educational rappelling, and kiosks, increased bouldering throughout visitor... signage.. Replace headquarters building, enlarge corrals, and move fence to true Refuge boundary.. Issue 6...

Brutally Unfair Tactics Totally OK Now

DEFF Research Database (Denmark)

Wilson, Douglas

2011-01-01

In this paper, I use a party game that I co-designed, Brutally Unfair Tactics Totally OK Now (B.U.T.T.O.N.), as a case study to suggest some alternative possibilities for the design of digitally-mediated play and games. Specifically, I argue that that intentionally “broken” or otherwise incomplet...

Primary treatment of pediatric plunging ranula with nonsurgical sclerotherapy using OK-432 (Picibanil).

Science.gov (United States)

Roh, Jong-Lyel; Kim, Hyo Sun

2008-09-01

Although surgery is the first choice of therapy for plunging ranula, it is associated with technical difficulties, morbidity and recurrence. Plunging ranula may be also primarily treated with nonsurgical sclerotherapy, but there is little experience in pediatric patients. We, therefore, assessed the efficacy of OK-432 sclerotherapy for pediatric plunging ranula. Nine children with plunging ranula were prospectively treated with intracystic injections of OK-432. At the outpatient clinic, the ranula was punctured in the neck and aspirated mucus was replaced with 0.1-0.2mg OK-432 solution. The size of the ranula was compared before and after sclerotherapy. Total or nearly total shrinkage was observed in 6 of 9 patients; marked reduction (>50% of original size) in 2; and partial reduction (<50% of original size) in 1. At a mean follow-up of 26 months after last sclerotherapy, recurrence was observed in only 1 patient; this patient showed complete response after reinjection of OK-432 solution. No significant complications were observed, with only fever and mild local pain observed in 4 patients for 2-4 days after treatment. OK-432 sclerotherapy is safe and effective in the treatment of pediatric plunging ranula. Sclerotherapy may become a primary treatment modality prior to surgery.

Alimentación temprana en pacientes aleatorizados poscolecistectomía laparascópica electiva en los Hospitales Vicente Corral Moscoso y José Carrasco Arteaga. 2013

OpenAIRE

Martínez Calderón, Hernán Patricio

2014-01-01

Objetivo: determinar los beneficios de la alimentación temprana en los pacientes sometidos a cirugía electiva de colecistectomía laparoscópica en los hospitales Vicente Corral Moscoso y José Carrasco Arteaga Metodología: se trató de unestudio de tipo experimental. La población de estudio fueron los pacientes de 18 a 60 años con indicaciones de colecistectomía laparoscópica, que acudieron al servicio de cirugía de los Hospitales Vicente Corral Moscoso y José Carrasco Arteaga, que fueron int...

Images and Metaphors, Mirrors of Social Concern in the Saga af Viktor ok Blavus

OpenAIRE

Mester, Annegret

2002-01-01

Images and Metaphors, Mirrors of Social Concern in the Saga af Viktor ok Blavus I wish to examine how the images and metaphors in the Saga af Viktor ok Blavus reflect the concerns of Icelandic society. Included among the metaphors are the personae which populate the saga. As in the Saints’ legends they are not characters but types and are therefore themselves metaphors. The opening stanzas of the Saga af Viktor ok Blavus comprise a reference to the translated riddarasögur which the ano...

8th February 2011-Rector Universidad Autónoma de Sinaloa Mexico Dr Victor Antonio Corrales Burgeño-Mexico-visiting ALICE cavern and tunnel with ALICE Spokesperson P. Giubellino

CERN Multimedia

Maximilien Brice

2011-01-01

Photo 1,3-14:The delegation visiting ALICE cavern Photo 2:Dra. Beatriz E. Rodríguez Pérez\tDirectora del Centro de Políticas de Género para la igualdad entre Hombres y Mujeres,Dr Victor Antonio Corrales Burgeño,P. Giubellino Photo 15-29:The delegation visiting LHC Tunnel Photo 30-57:Signature of the Guest Book with CERN Director-General R. Heuer and Head of International Relations F. Pauss Photo 58:Adviser for Mexico J. Salicio,ALICE Collaboration Universidad Autonoma de Sinaloa I. Leon Monzon,ALICE Collaboration Centro Invest. Estudios Avanz. IPN (Cinnestav) G. Herrera Corral,R. Heuer,Dr Victor Antonio Corrales Burgeño,F. Pauss,Dra. Beatriz E. Rodríguez Pérez,Directora de Relaciones InternacionalesMC. América M. Lizárraga González

Single-atom gating and magnetic interactions in quantum corrals

Energy Technology Data Exchange (ETDEWEB)

Ngo, Anh T.; Kim, Eugene H.; Ulloa, Sergio E.

2017-04-01

Single-atom gating, achieved by manipulation of adatoms on a surface, has been shown in experiments to allow precise control over superposition of electronic states in quantum corrals. Using a Green's function approach, we demonstrate theoretically that such atom gating can also be used to control the coupling between magnetic degrees of freedom in these systems. Atomic gating enables control not only on the direct interaction between magnetic adatoms, but also over superpositions of many-body states which can then control long distance interactions. We illustrate this effect by considering the competition between direct exchange between magnetic impurities and the Kondo screening mediated by the host electrons, and how this is affected by gating. These results suggest that both magnetic and nonmagnetic single-atom gating may be used to investigate magnetic impurity systems with tailored interactions, and may allow the control of entanglement of different spin states.

Treatment of lymphatic malformations of head and neck with OK-432 sclerotherapy induce systemic inflammatory response.

Science.gov (United States)

Närkiö-Mäkelä, Mervi; Mäkelä, Teppo; Saarinen, Pia; Salminen, Päivi; Julkunen, Ilkka; Pitkäranta, Anne

2011-01-01

Systemic immune responses after OK-432 (Picibanil) sclerotherapy in patients with head and neck lymphatic malformations (LM) were examined to achieve a better understanding of the mechanism of OK-432 sclerotherapy and to evaluate the long-term treatment outcome. Serum samples from 17 consecutive patients with head and neck LMs were collected during a total of 26 OK-432 treatment episodes. Serum C-reactive protein (CRP), interleukins (IL) 1β, 6, 8, 10, tumor necrosis factor (TNF)-α, interferon (IFN)-γ, RANTES, immune protein (IP)-10 and macrophage chemoattractant protein (MCP)-1 as well as blood leukocyte counts were determined. Clinical outcome of the treatment was evaluated at the last visit and from patient files. Elevated serum levels of IP-10 (means at baseline 702 ng/L, after 1 day 1180 ng/L, after 4 weeks 691 ng/L) were seen on day one after OK-432 sclerotherapy (p < 0.05). C-reactive protein and leukocyte counts 1 day after treatment differed statistically significantly (p < 0.05) from the baseline. No significant differences with other cytokines investigated were observed. Patients with macrocystic LM responded better than patients with microcystic LM (p = 0.01). The elevated levels of IP-10, C-reactive protein and leukocyte levels indicate that OK-432 sclerotherapy induces systemic immune responses in patients with LM. The mechanisms of OK-432 sclerotherapy are still not precisely understood, but the IP-10 elevation may reflect local antiangiogenetic properties of immunoactivation induced by OK-432.

The spatial module as environmental conditioning element: the Spanish pavilion by Corrales and Molezun

Directory of Open Access Journals (Sweden)

R. Suárez

2017-06-01

Full Text Available In the 50s a review of Modern Movement, which assimilates modular serialization and a connection with the environmental context, although with remote premises of the contemporary paradigms of sustainability arise. In this context, within national stage, stands out the Spanish pavilion at the Brussels International Exhibition in 1958 by Corrales and Molezún. This work seeks a quantitatively reveal of the environmental performance of the pavilion in its two locations and settings, in Brussels and Madrid, through simulation and analysis of energy and lighting models which reproduces the characteristic of the pavilion with the purpose of contributing to give a new critical point of view, valuing the module efficiency to adapt to different environmental conditions. The completed analysis reveals the influence of the climate, compactness and orientation, as in the difficulties associated with thermal comfort and natural light when glazing percentage are important and there are high solar radiation settings.

Análisis tipológico de las estructuras de las construcciones rurales tradicionales de barro. La casa de corral en el Páramo de León (España

Directory of Open Access Journals (Sweden)

Rego Sanmartín, Teresa

2000-08-01

Full Text Available Traditional rural buildings reflect the building techniques inherited from ancestors, where materials mastery is proved. In this job we analyse the structure of one of the most relevant Spanish traditional agrarian building: the "casa de corral"(yard house. Thirty seven "corrales" (yards of the vernacular earthen construction in the "Páramo de León"(León, Spain were analysed. It was necessary think up an analysis method, which we called "round analysis method". Generally. radial cross sections of the yard have a main space between two earth walls bearing over stone foundation, which support floor framing, the roof framing, roof sheathing and arabic curved tiles. A gantry is usually built inward the yard, on a stone baseLas construcciones rurales tradicionales suelen reflejar el buen hacer de quienes han heredado las técnicas de sus antepasados, demostrando un dominio admirable de los materiales. En este trabajo nos centramos en el análisis estructural de uno de los edificios más emblemáticos de las construcciones agrarias tradicionales peninsulares: la casa de corral. Se analizaron 37 de estos edificios, uniformemente repartidos por la comarca del Páramo de León (España. pertenecientes a la denominada construcción de barro rural tradicional contemporánea. Para llevar a cabo el estudio fue necesario idear el denominado método giratorio de análisis. en virtud del cual se realizan sucesivos cortes radiales al corral. Esto nos permitió establecer las características constructivas más relevantes de dichos edificios. En general. las secciones radiales del corral suelen contar con un volumen principal de gruesos muros de carga a base de tapial sobre cimiento de piedra. sustentando los forjados y la estructura de cubierta, cuya impermeabilidad se logra mediante teja árabe. dispuesta sobre enlabiado de madera o sobre rama entretejida. Hacia el interior del corral se suele construir el corredor porticado, cuyos soportes transmiten las

77 FR 19691 - Notice of Inventory Completion: Sam Noble Oklahoma Museum of Natural History, Norman, OK

Science.gov (United States)

2012-04-02

... Natural History, Norman, OK. The human remains and associated funerary objects were removed from Le Flore... Flore County, OK. The mound site was excavated by the Works Progress Administration (WPA), under the...

Authenticity and origin of prehispanic ceramic material, analysis of zapotecan urns of the Ontario Real Museum; Autenticidad y origen de material ceramico prehispanico, analisis de urnas zapotecas del Museo Real de Ontario

Energy Technology Data Exchange (ETDEWEB)

Ramirez L, A.; Schaaf, P. [Instituto de Geofisica, UNAM, 04510 Mexico D.F. (Mexico); Martinez, Y.; Ortiz D, E.; Lazos, L. [Instituto de Investigaciones Antropologicas, UNAM, 04510 Mexico D.F. (Mexico); Ruvalcaba, J.L. [IFUNAM, 04510 Mexico D.F. (Mexico); Sellen, A. [Dep. de Antropologia, Museo Real de Ontario (Canada)

2003-07-01

The Zapotec culture flourished approximately in Oaxaca of the year 220 B.C. up to the 800 D.C., in their funeral acts the Zapotec often took to the tomb to their deads accompanied of rich offerings including a great variety of ceramic, one of these varieties of ceramics were those urns that are kind of an adorned vessels with a sphinx, that is to say, a cylinder that has incorporate a figure generally anthropomorphous, which represented ancestres or divinities, the size of these urns went from the 15 cm until but of a meter high. At the beginning of the XX century the urns got the attention of the collectors and a number important of replies (false) they were manufactured copying the original ones, in this time C. Rickards gathers one of those but important collections of urns zapotec, in 1919 the Real Museum of Ontario (ROM) acquired the collection Rickards, in the 70 s they were practiced test of authenticity for thermoluminescence indicating that 36 of these urns were false, comparing their iconography with the other urns of the collection suggests the possibility that at least 80 of these pieces are not you authenticate. In this work the results are presented by thermoluminescence carried out to 17 pieces of the collection Rickards property of the Real Museum of Ontario like part of a first one work stage, for they were perforated it the urns with a drill of tungsten carbide extracting 50 milligrams approximately, of which 25 were used for thermoluminescence and the rest for analysis for X ray Emission Spectroscopy. Proton Induced X-ray Emission (PIXE) and for X-ray Diffraction (XRD). The test of authenticity for thermoluminescence beginning with the determination of the rate of annual dose starting from the determination of the concentration of the natural radioisotopes of uranium ({sup 238} U) and torio ({sup 232} Th) by means of an accountant of particles alpha, the potassium ({sup 40} K) by means of X-ray diffraction, later on the sample was treated

Treatment of lymphatic malformations with OK-432 (Picibanil): review of the literature.

Science.gov (United States)

Poldervaart, Michelle T; Breugem, Corstiaan C; Speleman, Lucienne; Pasmans, Suzanne

2009-07-01

Lymphatic malformations (LM) are benign structural defects that can cause serious complications because of their size and location. Traditionally, surgical removal was the first treatment modality, but this could be associated with many complications and risks. Since Ogita introduced OK-432 (picibanil) in 1987 as a treatment method, this sclerosant has become popular. This paper is a review of the trials published so far on this topic. A literature search of English trials with 5 or more patients in it with LM who had never been treated before was done. The paper had to use the microcystic-macrocystic classification and have a mean follow-up of more than a year to be included in this review. Results were classified as "excellent" when the lesions show a regression of more than 90%, "good" when regression is more than 50%, and "poor" when shrinkage is less than 50% (this also includes no response at all). Twenty-seven percent of microcystic LMs show an excellent result; 33%, a good result; and 40%, a poor result. Of the macrocystic LMs, 88% have excellent results. Recurrence rates vary from 5% to 8%. The adverse effects are mostly mild. Most trials have a short follow-up; therefore, there are uncertainties when it comes to cure and regression. Mostly, the adverse effects of OK-432 are trivial and disappear after a week, but the need for a temporary tracheostomy has been described. Screening for allergic reactions to penicilline is needed, with the risk of anaphylactic shock in mind. It is difficult to compare the different techniques used by the authors, and none of the trials included in this study are randomized controlled trials; most are retrospective and were so-called level 4 studies. This review demonstrates that OK-432 is an effective way to treat LM. Because of a possible risk of airway obstruction, treatment should always take place in specialized treatment facilities. Macrocystic lesions show a better response to OK-432 treatment than microcystic lesions

Evaluation of OK-432 Injection Therapy as Possible Primary Treatment of Intraoral Ranula.

Science.gov (United States)

Kono, Michihide; Satomi, Takafumi; Abukawa, Harutsugi; Hasegawa, On; Watanabe, Masato; Chikazu, Daichi

2017-02-01

A ranula is a pseudocyst caused by mucous extravasation from the sublingual gland. Recently, a sclerosing agent, OK-432 (picibanil), has been reported to be highly effective for treating lymphangioma and cervical cystic lesions. The present study assessed the effectiveness of OK-432 injection therapy for intraoral ranula to clarify whether it can be used as the primary treatment. The present study was a retrospective clinical study of patients with intraoral ranula who received OK-432 injection therapy from 2005 to 2015. The ranula size was measured on computed tomography or magnetic resonance imaging studies. We dissolved 1 Klinische Einheit (KE) unit of OK-432 powder in normal saline equal to the aspiration volume. The primary endpoint was the treatment results. The secondary endpoints were the relation between the treatment results and the lesion length and aspiration volume. A total of 23 patients received OK-432 injection therapy for an intraoral ranula. The mean lesion size was 19.96 mm. The mean aspiration volume was 2.14 mL. The number of injections was 1 to 4 (mean 1.70). The treatment results were complete regression (CR) in 18 (78.2%), partial regression (PR) in 3 (13.0%), and no response (NR) in 2 (8%) patients after the last injection. The overall efficacy rate was 91.2% (21 of 23). No serious complications were observed. The lesion length and aspiration volume of the CR group was 17.38 mm and 1.40 mL, respectively. The lesion length and aspiration volume of the PR/NR group was 29.20 mm and 4.80 mL, respectively. The PR/NR group lesions were significantly larger than the CR group lesions. OK-432 injection therapy for intraoral ranula is safe and effective compared with other surgical therapies. This therapy could potentially become a primary treatment of intraoral ranula. Copyright © 2016 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

Tõeline elamus: Oks ja Edur viimast korda kodulaval / Kristiina Garancis

Index Scriptorium Estoniae

Garancis, Kristiina, 1969-

2009-01-01

7. veebruaril Jõhvi kontserdimajas balletifestivali raames etendunud P. Tšaikovski balletist "Uinuv kaunitar" Peterburi Riikliku Klassikalise Balleti Teatri trupi esituses, peaosades Age Oks, Toomas Edur

Chemotherapy and Sex: Is Sexual Activity OK during Treatment?

Science.gov (United States)

... OK during treatment? Is it safe to have sex with my husband while undergoing chemotherapy? Answers from ... best to discuss any concerns about chemotherapy and sex with your doctor, who's familiar with your individual ...

Žurnāla SHAPE pārpozicionēšanas stratēģijas problēmas un risinājumi.

OpenAIRE

Nikodemusa, Zane

2013-01-01

Maģistra darba tēma ir „Žurnāla SHAPE pārpozicionēšanas stratēģijas problēmas un risinājumi”. Maģistra darba mērķis ir izpētīt žurnāla SHAPE pārpozicionēšanas stratēģiju, tās ieguvumus un zaudējumus no uzņēmuma skatu punkta, kā arī ietekmējošos faktorus un risinājumus turpmākai tirgus pozīcijas stiprināšanai. Darba gaitā autore izmanto dažādas informācijas apkopošanas un analīzes metodes. Teorētiskās daļas veidošanai darba autore izmantoja literatūras referatīvās analīzes metodi. Informāci...

Effect of soluble factors derived from oral cancer cells on the production of interferon-γ from peripheral blood mononuclear cells following stimulation with OK-432.

Science.gov (United States)

Ohe, Go; Sasai, Akiko; Uchida, Daisuke; Tamatani, Tetsuya; Nagai, Hirokazu; Miyamoto, Youji

2013-08-01

The streptococcal antitumor agent OK-432 is commonly used as an immunopotentiator for immunotherapy in various types of malignant tumors including oral cancer. It has been demonstrated that OK-432 elicits an antitumor effect by stimulating immunocompetent cells, thereby inducing multiple cytokines including interferon (IFN)-γ, interleukin (IL)-2 and IL-12. Serum concentrations of IFN-γ in patients with oral cancer were examined 24 h after administration of OK-432. Serum concentrations of IFN-γ in patients with advanced cancer were significantly lower than those in patients with early cancer. These results suggested that some soluble factors produced by cancer cells may inhibit IFN-γ production with OK-432. Thus, in the present study, an in vitro simulation model was established for the immune status of patients with oral cancer by adding conditioned medium (CM) derived from oral cancer cell lines into a culture of peripheral blood mononuclear cells (PBMCs) derived from a healthy volunteer. We investigated whether soluble factors derived from oral cancer cells affected IFN-γ production from PBMCs following stimulation with OK-432. PBMCs stimulated with OK-432 produced a large amount of IFN-γ; however, both IFN-γ production and cytotoxic activity from PBMCs induced by OK-432 were inhibited by the addition of CM in a dose-dependent manner. In order to examine these inhibitory effects against IFN-γ production, the contribution of inhibitory cytokines such as IL-4, IL-6, IL-10, transforming growth factor-β and vascular endothelial growth factor was investigated. However, neutralization of these inhibitory cytokines did not recover IFN-γ production inhibited by CM. These results indicated that unknown molecules may inhibit IFN-γ production from PBMCs following stimulation with OK-432.

Archaeological Investigations at Sites 45-OK-2 and 45-OK-2A, Chief Joseph Dam Project, Washington.

Science.gov (United States)

1984-01-01

on the floor of Feature 49. RANUNCULACEAE (Buttercup Family ) Clematis L. (virgin’s bower) , A small section of clematis stem was found in occupation...assemblage, 4,951 fragments (approximately 2%) were identified to at least the family level. Eighty-eight percent of the Identified elements represented...93 elements, 45-OK-2A -- 28 elements. Snake vertebrae were Identified to family on the basis of size. There are _1 at least four species of snakes

Post-irradiation treatment with OK432 can prevent radiation-induced bone marrow death

International Nuclear Information System (INIS)

Kurishita, A.; Uehara, Y.; Tohoku Univ., Sendai; Katoh, H.; Hirose, S.; Uchida, A.; Mizutani, Y.; Okada, S.; Ono, T.

1991-01-01

The radioprotective effect of OK432, a Streptocuccus haemolyticus preparation, on bone marrow death was examined in mice. The LD 50 value was increased from 7.55 Gy in controls to 8.45 Gy in mice treated once with OK432 immediately after irradiation. Multiple administration of the agent further elevated the LD 50 value to 9.56 Gy. The radioprotective effect was also apparent when multiple treatments were commenced as late as 72 h after irradiation. (author)

Corral Monitoring System assessment results

International Nuclear Information System (INIS)

Filby, E.E.; Haskel, K.J.

1998-03-01

This report describes the results of a functional and operational assessment of the Corral Monitoring Systems (CMS), which was designed to detect and document accountable items entering or leaving a monitored site. Its development was motivated by the possibility that multiple sites in the nuclear weapons states of the former Soviet Union might be opened to such monitoring under the provisions of the Strategic Arms Reduction Treaty. The assessment was performed at three levels. One level evaluated how well the planned approach addressed the target application, and which involved tracking sensitive items moving into and around a site being monitored as part of an international treaty or other agreement. The second level examined the overall design and development approach, while the third focused on individual subsystems within the total package. Unfortunately, the system was delivered as disassembled parts and pieces, with very poor documentation. Thus, the assessment was based on fragmentary operating data coupled with an analysis of what documents were provided with the system. The system design seemed to be a reasonable match to the requirements of the target application; however, important questions about site manning and top level administrative control were left unanswered. Four weaknesses in the overall design and development approach were detected: (1) poor configuration control and management, (2) inadequate adherence to a well defined architectural standard, (3) no apparent provision for improving top level error tolerance, and (4) weaknesses in the object oriented programming approach. The individual subsystems were found to offer few features or capabilities that were new or unique, even at the conceptual level. The CMS might possibly have offered a unique combination of features, but this level of integration was never realized, and it had no unique capabilities that could be readily extracted for use in another system

Corral Monitoring System assessment results

Energy Technology Data Exchange (ETDEWEB)

Filby, E.E.; Haskel, K.J.

1998-03-01

This report describes the results of a functional and operational assessment of the Corral Monitoring Systems (CMS), which was designed to detect and document accountable items entering or leaving a monitored site. Its development was motivated by the possibility that multiple sites in the nuclear weapons states of the former Soviet Union might be opened to such monitoring under the provisions of the Strategic Arms Reduction Treaty. The assessment was performed at three levels. One level evaluated how well the planned approach addressed the target application, and which involved tracking sensitive items moving into and around a site being monitored as part of an international treaty or other agreement. The second level examined the overall design and development approach, while the third focused on individual subsystems within the total package. Unfortunately, the system was delivered as disassembled parts and pieces, with very poor documentation. Thus, the assessment was based on fragmentary operating data coupled with an analysis of what documents were provided with the system. The system design seemed to be a reasonable match to the requirements of the target application; however, important questions about site manning and top level administrative control were left unanswered. Four weaknesses in the overall design and development approach were detected: (1) poor configuration control and management, (2) inadequate adherence to a well defined architectural standard, (3) no apparent provision for improving top level error tolerance, and (4) weaknesses in the object oriented programming approach. The individual subsystems were found to offer few features or capabilities that were new or unique, even at the conceptual level. The CMS might possibly have offered a unique combination of features, but this level of integration was never realized, and it had no unique capabilities that could be readily extracted for use in another system.

Energy content of hybrid Rumex patienta L. x Rumex tianschanicus A. Los. (Rumex OK 2 samples from autumn months

Directory of Open Access Journals (Sweden)

Michal Rolinec

2018-03-01

Full Text Available Aim of this experiment was to determine the gross energy concentration of fresh, wilted and ensiled hybrid of Rumex patientia L. x Rumex tianschanicus A. Los. (Rumex OK 2. Samples were collected in autumn months of the year 2017. The plant of Rumex OK 2 consist during autumn months only from rosette of leaves. The height of leaves was in autumn months following, September 56.68±13.80 cm; October 59.29±11.93 cm and November 55.98±10.80 cm. Rumex OK 2 silage was made from wilted matter, with or without of addition of dried molasses. Gross energy was determined as the heat released after combustion of a sample (Leco AC 500 in MJ per kilogram of dry matter of the sample. By the autumn months the concentration of dry matter, as well as the concentration of gross energy increased, except Rumex OK 2 silage from November. The highest concentration of gross energy had wilted Rumex OK 2 from November (18.02 MJ.kg-1 of dry matter. There was no significant effect of addition of dried molasses to wilted Rumex OK 2 before ensiling on gross energy concentration in Rumex OK 2 silages (P>0.05. Gross energy concentration of all types of analysed samples had relative high value (16.98 to 18.02 MJ.kg-1 of dry matter. Fresh or ensiled Rumex OK 2 can be used as a part of feed ratio for ruminants or can be utilised in biogas station. However, due to the low content of dry mater in fresh or wilted material the production of silage can be in autumn months problematic.

Vīrieša tēls patērētāju priekšstatos: žurnāla "Klubs" 2014. gada reklāmu analīze

OpenAIRE

Blumberga, Lelde

2015-01-01

Bakalaura darba ”Vīriešu tēls patērētāju priekšstatos: žurnāla „Klubs” 2014. gada reklāmu analīze” mērķis ir noskaidrot, kāds vīrieša tēls tiek veidots vīriešu žurnālu reklāmas un tā patērētāja priekšstatos. Darba pētnieciskā problēma paredz, ka vīriešu tēls vīriešu žurnālos tiek pasniegts kā spilgts, veiksmīgs un ietekmīgs, kas var atstāt iespaidu uz patērētāja apziņu. Darbs sastāv no trīs daļām – teorētiskās, metodoloģiskās un empīriskās. Darba teorētiskajā daļā tiks apskatīta teorij...

75 FR 5015 - Television Broadcasting Services; Oklahoma City, OK

Science.gov (United States)

2010-02-01

...] Television Broadcasting Services; Oklahoma City, OK AGENCY: Federal Communications Commission. ACTION... procedures for comments, see 47 CFR 1.415 and 1.420. List of Subjects in 47 CFR Part 73 Television, Television broadcasting. For the reasons discussed in the preamble, the Federal Communications Commission...

Manual de procesos de gestión financiera aplicado al Hospital Provincial General Docente Vicente Corral Moscoso

OpenAIRE

Rojas Ortega, Angélica Magdalena; Trelles Torres, Silvia América

2007-01-01

La motivación de esta tesis fue el emplear conocimientos adquiridos en el transcurso de nuestros estudios académicos e investigaciones, en una Institución Pública como es el Hospital "Vicente Corral Moscoso". Nuestro estudio consta de seis capítulos en los cuales describimos varios conceptos y elementos importantes para la comprensión de este manual, en una Institución del Sector Público no Financiero, donde intervienen leyes, disposiciones legales y acuerdos vigentes emitidos por el Minis...

[Effect of intravenous treatment with OK-432 on the bone marrow in patients with lung cancer].

Science.gov (United States)

Fujii, M; Ishikawa, M; Toki, H

1984-03-01

We studied effects of OK-432 on the bone marrow and peripheral blood cells of lung cancer patients. The nuclear cell count of bone marrow increased in 5 to 7 patients upon intravenous treatment with OK-432 compared with 3 of 6 patients who were intramuscularly treated with OK-432. Serial neutrophil counts of bone marrow increased in all 7 patients treated intravenously compared with 3 of 6 patients treated intramuscularly. The mean nuclear cell count or the serial neutrophil count of bone marrow in intravenously treated patients was significantly higher than the pretreatment values (p less than 0.001). In the peripheral blood picture, the difference in white blood cells or neutrophils before and after intravenous treatment was also statistically significant (p less than 0.01). There was no change in the erythrocytic series count of bone marrow and the hemoglobin count. Our results support the superiority of intravenous OK-432 treatment over intramuscular treatment in the growth-accelerating effect on bone marrow cells, especially regarding the neutrophil series.

Treatment of lymphangiomas with OK-432 (Picibanil) sclerotherapy: a prospective multi-institutional trial.

Science.gov (United States)

Giguère, Chantal M; Bauman, Nancy M; Sato, Yutaka; Burke, Diane K; Greinwald, John H; Pransky, Seth; Kelley, Peggy; Georgeson, Keith; Smith, Richard J H

2002-10-01

To describe and to determine the robustness of our study evaluating the efficacy of OK-432 (Picibanil) as a therapeutic modality for lymphangiomas. Prospective, randomized trial and parallel-case series at 13 US tertiary care referral centers. Thirty patients diagnosed as having lymphangioma. Ages in 25 ranged from 6 months to 18 years. Twenty-nine had lesions located in the head-and-neck area. Every patient received a 4-dose injection series of OK-432 scheduled 6 to 8 weeks apart unless a contraindication existed or a complete response was observed before completion of all injections. A control group was observed for 6 months. Successful outcome of therapy was defined as a complete or a substantial (>60%) reduction in lymphangioma size as determined by calculated lesion volumes on computed tomographic or magnetic resonance imaging scans. Overall, 19 (86%) of the 22 patients with predominantly macrocystic lymphangiomas had a successful outcome. OK-432 should be efficacious in the treatment of lymphangiomas. Our study design is well structured to clearly define the role of this treatment agent.

75 FR 13236 - Television Broadcasting Services; Oklahoma City, OK

Science.gov (United States)

2010-03-19

... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 [DA 10-395; MB Docket No. 10-19; RM-11589] Television Broadcasting Services; Oklahoma City, OK AGENCY: Federal Communications Commission. ACTION: Final... review Act, see 5 U.S.C. 801(a)(1)(A). List of Subjects in 47 CFR Part 73 Television, Television...

Treatment of Primary Fetal Hydrothorax with OK-432 (Picibanil): Outcome in 14 Fetuses and a Review of the Literature.

Science.gov (United States)

O'Brien, Brooke; Kesby, Greg; Ogle, Robert; Rieger, Ingrid; Hyett, Jon A

2015-01-01

Primary fetal hydrothorax (PFHT) is an uncommon condition with an estimated prevalence of 1 in 10,000/15,000 pregnancies. Therapeutic interventions include thoracocentesis, thoraco-amniotic shunting (TAS), and pleurodesis using OK-432. A review of the literature was performed to identify all cases of PFHT treated with TAS and OK-432. All cases of PFHT referred to the Fetal Maternal Unit at Royal Prince Alfred Hospital between 2002 and 2012 were retrospectively reviewed. In the cohort of fetuses treated with OK-432, the main perinatal outcomes evaluated were termination of pregnancy, live birth, neonatal death, and fetal death in utero. Secondary outcomes included gestational age (GA) at diagnosis, GA at treatment, GA at resolution, birth weight, and GA at birth. The development of the children was screened using the Ages and Stages Questionnaires, Version 3 (ASQ-3, 2009). Primary hydrothorax was diagnosed in 31 fetuses, of which 14 had treatment with OK-432. One pregnancy terminated after treatment with OK-432. Survival was 85% (11/13): 100% in fetuses treated with OK-432 without hydrops, and 78% in those treated with hydrops. This compares well to the cases of TAS in the literature with an average survival of 63%: 85% in fetuses without hydrops and 55% with hydrops. The mean GA at birth was 36(+4) weeks and mean birth weight 3,007 g. Eight of the 9 children screened with ASQ-3 scored well within the normal range. OK-432 appears to be a valid treatment option in fetuses with PFHT, particularly in those diagnosed at early GAs. © 2014 S. Karger AG, Basel.

Characterization of the audiologic thresholds in workers of funeral urns

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Pereira, José Roberto

2009-09-01

Full Text Available Introduction: The industrial technological advance has brought benefits and a series of implications that may commit the worker's health and life quality. The exposure to physical, chemical agents and organizational stressors contribute for the increase of work accidents risks. The noise, taken as the most frequent physical agent in the work environment, may cause auditory alterations called Noise-Induced Hearing Loss that affect the communication and life quality of the workers. Objective: To research the auditory health of employees in a funeral urns factory. Method: 90 workers took part in this study, aged between 16 and 52 years, exposed to sound pressure levels equal or higher than 85 dBNPS, vibration and/or chemical agents in the work environment. We carried out a specific interview and Threshold Tonal Audiometry. Results: This study identified altered audiometry results in 13.33% the right ear and 16.67% in the left ear and the age also influenced these auditory thresholds. Conclusion: The accomplishment of a workers' health surveillance program with all people involved is critical and will contribute for the human resources formation, in the management to proceed with actions as well as those by the proper workers being careful of their health.

Experimental intraperitoneal infusion of OK-432 in rats: Evaluation of peritoneal complications and pathology

Energy Technology Data Exchange (ETDEWEB)

Kim, Dong Wook [Department of Radiology, Busan Paik Hospital, Inje University College of Medicine, Busan (Korea, Republic of); Kim, Hak Jin, E-mail: hakjink@pusan.ac.k [Department of Radiology, Pusan National University Hospital, Pusan National University College of Medicine, Medical Research Institute, Busan (Korea, Republic of); Lee, Jun Woo [Department of Radiology, Pusan National University Hospital, Pusan National University College of Medicine, Medical Research Institute, Busan (Korea, Republic of)

2010-06-15

Purpose: OK-432 is known to be a potent sclerosant of cystic lesions. The purpose of this study was to evaluate both its safety and pathologic effects after the infusion of OK-432 into the peritoneal cavity of rats. Materials and methods: Twenty male rats were used in this study. Twelve rats were infused intraperitoneally with 0.2 Klinishe Einheit of OK-432 melted in 2 mL of normal saline (group 1: the treated group); four rats each were infused intraperitoneally with 0.5 mL of 99% ethanol (group 2) and normal saline (group 3), and served as the control groups. An abdominal ultrasonographic examination was performed both before and after the infusions in all rats. Three rats in group 1 and one rat in each of groups 2 and 3 were sacrificed each week following the infusion. Gross and microscopic evaluations of the peritoneum and abdominal cavity were performed on each rat. Results: In group 1, the abdomen was clear on gross inspection and the peritoneum was unremarkable on microscopic examination. In group 2, mild-to-moderate peritoneal adhesions were revealed grossly, and inflammation and fibrosis of the peritoneum were demonstrated microscopically. In group 3, no specific abnormalities were noted on gross or microscopic examinations. Conclusion: Leakage or abnormal infusion of OK-432 solution into the peritoneal cavity during sclerotherapy of intra-abdominal or retroperitoneal cystic lesions does not result in any significant complications.

Experimental intraperitoneal infusion of OK-432 in rats: Evaluation of peritoneal complications and pathology

International Nuclear Information System (INIS)

Kim, Dong Wook; Kim, Hak Jin; Lee, Jun Woo

2010-01-01

Purpose: OK-432 is known to be a potent sclerosant of cystic lesions. The purpose of this study was to evaluate both its safety and pathologic effects after the infusion of OK-432 into the peritoneal cavity of rats. Materials and methods: Twenty male rats were used in this study. Twelve rats were infused intraperitoneally with 0.2 Klinishe Einheit of OK-432 melted in 2 mL of normal saline (group 1: the treated group); four rats each were infused intraperitoneally with 0.5 mL of 99% ethanol (group 2) and normal saline (group 3), and served as the control groups. An abdominal ultrasonographic examination was performed both before and after the infusions in all rats. Three rats in group 1 and one rat in each of groups 2 and 3 were sacrificed each week following the infusion. Gross and microscopic evaluations of the peritoneum and abdominal cavity were performed on each rat. Results: In group 1, the abdomen was clear on gross inspection and the peritoneum was unremarkable on microscopic examination. In group 2, mild-to-moderate peritoneal adhesions were revealed grossly, and inflammation and fibrosis of the peritoneum were demonstrated microscopically. In group 3, no specific abnormalities were noted on gross or microscopic examinations. Conclusion: Leakage or abnormal infusion of OK-432 solution into the peritoneal cavity during sclerotherapy of intra-abdominal or retroperitoneal cystic lesions does not result in any significant complications.

Polycyclic aromatic hydrocarbons in sediments and mussels of Corral Bay, south central Chile.

Science.gov (United States)

Palma-Fleming, Hernan; P, Adalberto J Asencio; Gutierrez, Elena

2004-03-01

PAHs were measured in sediments and mussels (Mytilus chilensis) from Carboneros and Puerto Claro, located in Corral Bay, Valdivia. According to the ratio of phenanthrene/anthracene and fluoranthene/pyrene concentrations, these sites are medium polluted with PAHs originating mainly from pyrolytic sources. Fluoranthene was the major component measured in mussels (3.1-390 ng g(-1) dry weight) and sediments (6.9-74.1 ng g(-1) dry weight). In general, mussels were mainly exposed to the dissolved fraction of the lower molecular weight PAHs (tri- and tetra-aromatics) while the higher molecular ring systems (penta- and hexa-aromatics) were more bioavailable to sediments. Mussel PAHs content was relatively constant, with the exception of the 1999 summer season (March), when higher concentration values were found in both sites; however, PAHs residues in sediments showed a temporal variation.

Adaptive Surface Modeling of Soil Properties in Complex Landforms

Directory of Open Access Journals (Sweden)

Wei Liu

2017-06-01

Full Text Available Abstract: Spatial discontinuity often causes poor accuracy when a single model is used for the surface modeling of soil properties in complex geomorphic areas. Here we present a method for adaptive surface modeling of combined secondary variables to improve prediction accuracy during the interpolation of soil properties (ASM-SP. Using various secondary variables and multiple base interpolation models, ASM-SP was used to interpolate soil K+ in a typical complex geomorphic area (Qinghai Lake Basin, China. Five methods, including inverse distance weighting (IDW, ordinary kriging (OK, and OK combined with different secondary variables (e.g., OK-Landuse, OK-Geology, and OK-Soil, were used to validate the proposed method. The mean error (ME, mean absolute error (MAE, root mean square error (RMSE, mean relative error (MRE, and accuracy (AC were used as evaluation indicators. Results showed that: (1 The OK interpolation result is spatially smooth and has a weak bull's-eye effect, and the IDW has a stronger ‘bull’s-eye’ effect, relatively. They both have obvious deficiencies in depicting spatial variability of soil K+. (2 The methods incorporating combinations of different secondary variables (e.g., ASM-SP, OK-Landuse, OK-Geology, and OK-Soil were associated with lower estimation bias. Compared with IDW, OK, OK-Landuse, OK-Geology, and OK-Soil, the accuracy of ASM-SP increased by 13.63%, 10.85%, 9.98%, 8.32%, and 7.66%, respectively. Furthermore, ASM-SP was more stable, with lower MEs, MAEs, RMSEs, and MREs. (3 ASM-SP presents more details than others in the abrupt boundary, which can render the result consistent with the true secondary variables. In conclusion, ASM-SP can not only consider the nonlinear relationship between secondary variables and soil properties, but can also adaptively combine the advantages of multiple models, which contributes to making the spatial interpolation of soil K+ more reasonable.

OkCupid Data for Introductory Statistics and Data Science Courses

Science.gov (United States)

Kim, Albert Y.; Escobedo-Land, Adriana

2015-01-01

We present a data set consisting of user profile data for 59,946 San Francisco OkCupid users (a free online dating website) from June 2012. The data set includes typical user information, lifestyle variables, and text responses to 10 essay questions. We present four example analyses suitable for use in undergraduate introductory probability and…

The bacterial preparation OK432 induces IL-12p70 secretion in human dendritic cells in a TLR3 dependent manner.

Science.gov (United States)

Hovden, Arnt-Ove; Karlsen, Marie; Jonsson, Roland; Appel, Silke

2012-01-01

Dendritic cells (DC) used in therapeutic cancer immunotherapy have to be able to stimulate T cells resulting in an immune response that can efficiently target the cancer cells. One of the critical hurdles has been the lack of IL-12p70 production when maturating the DC, which is rectified by using the bacterial preparation OK432 (trade name Picibanil) to mature the cells. In order to identify the mechanism behind OK432 stimulation of DC, we investigated the contribution of different TLR to examine their involvement in IL-12p70 production. By combining different inhibitors of TLR signaling, we demonstrate here that TLR3 is responsible for the IL-12p70 production of DC induced by OK432. Moreover, our data suggest that the ligand triggering IL-12p70 secretion upon TLR3 stimulation is sensitive to proteinase and partly also RNAse treatment. The fact that a bacterial compound like OK432 can activate the TLR3 pathway in human DC is a novel finding. OK432 demonstrates a critical ability to induce IL-12p70 production, which is of great relevance in DC based cancer immunotherapy.

The bacterial preparation OK432 induces IL-12p70 secretion in human dendritic cells in a TLR3 dependent manner.

Directory of Open Access Journals (Sweden)

Arnt-Ove Hovden

Full Text Available Dendritic cells (DC used in therapeutic cancer immunotherapy have to be able to stimulate T cells resulting in an immune response that can efficiently target the cancer cells. One of the critical hurdles has been the lack of IL-12p70 production when maturating the DC, which is rectified by using the bacterial preparation OK432 (trade name Picibanil to mature the cells. In order to identify the mechanism behind OK432 stimulation of DC, we investigated the contribution of different TLR to examine their involvement in IL-12p70 production. By combining different inhibitors of TLR signaling, we demonstrate here that TLR3 is responsible for the IL-12p70 production of DC induced by OK432. Moreover, our data suggest that the ligand triggering IL-12p70 secretion upon TLR3 stimulation is sensitive to proteinase and partly also RNAse treatment. The fact that a bacterial compound like OK432 can activate the TLR3 pathway in human DC is a novel finding. OK432 demonstrates a critical ability to induce IL-12p70 production, which is of great relevance in DC based cancer immunotherapy.

Modification of radiation therapy by RP-170, hypoxic cell sensitizer and OK-432, biological response modifier (BRM)

International Nuclear Information System (INIS)

Murayama, Chieko; Mori, Tomoyuki; Tamauchi, Hidekazu

1995-01-01

Studies have shown that the combination therapy with RP-170, irradiation and OK-432 could produce significantly higher antitumor effect. The multiple local administration of OK-432 showed superior sensitizing effect in tumor growth delay, tumor control and survival rate. DMF from TCD 50 assay was 2.09 which might be equivalent to that from irradiation with over several hundred mg/kg of RP-170. Additionally combined with 50 mg/kg RP-170, nearly available dose in clinical use, the combined treatment with RP-170, irradiation and OK-432 produced DMF of 1.4, which could be gotten by over 100 mg/kg of RP-170. The success of this combination therapy on murine tumors might also suggest a possibility for a great benefit in clinical radiotherapy. More detailed investigations, histological and immunological research, are under progress. 14 refs., 2 tabs., 3 figs

Apendicectomías no enfermas en el Hospital Vicente Corral Moscoso y Hospital José Carrasco Arteaga, Cuenca 2014

OpenAIRE

Montero Tapia, Edgar Paúl

2016-01-01

Objetivo General Determinar la prevalencia de Apendicectomías No Enfermas en pacientes mayores de 15 años en el servicio de cirugía del Hospital Vicente Corral Moscoso y Hospital José Carrasco Arteaga durante el 2014. Método: Se realizó un estudio transversal, en 300 pacientes sometidos a apendicectomía de los HVCM y HJCA en la Ciudad de Cuenca; se recogieron datos demográficos, cuadro clínico, resultados de exámenes complementarios de sangre y resultados de la escala de Alvarado y RIP...

Sclerotherapy of cervical cysts with Picibanil (OK-432).

Science.gov (United States)

Knipping, Stephan; Goetze, Gerrit; Neumann, Kerstin; Bloching, Marc

2007-04-01

The effectiveness of intralesional sclerotherapy of lymphangiomas and ranulas with OK-432 (Picibanil) has been proved in several clinical studies. The aim of our study was to review the effectiveness of sclerotherapy of benign cervical cysts with Picibanil as an alternative method to surgical excision. Between March 2002 and March 2006, a prospective observational study was carried out to assess the effects of Picibanil on cervical cysts. Between 2002 and 2006 we treated 14 patients having cervical cysts through intralesional application of Picibanil with a dose of 0.01 mg/ml. So far we used Picibanil with 13 patients achieving a high success rate. In eight cases we observed, both clinically and ultrasonographically, a nearly complete regression, and a complete regression of the cysts in three cases. In two cases the cysts atrophied. In these cases only residual findings could be observed. In one case we extirpated the remaining cyst. If there is no clear reaction of the cyst to the treatment, an excision is indicated 6 weeks after the injections to gain meaningful histological examination. No significant complication after sclerotherapy with Picibanil was observed. According to our results the application of OK-432 (Picibanil) is a safe and effective primary method for sclerotherapy of benign cervical cysts which can replace surgical extirpation in special cases. However, the risk of malign diseases has to be excluded before the commencement of the Picibanil treatment.

Scanning tunneling microscopic images and scanning tunneling spectra for coupled rectangular quantum corrals

International Nuclear Information System (INIS)

Mitsuoka, Shigenori; Tamura, Akira

2011-01-01

Assuming that an electron confined by double δ-function barriers lies in a quasi-stationary state, we derived eigenstates and eigenenergies of the electron. Such an electron has a complex eigenenergy, and the imaginary part naturally leads to the lifetime of the electron associated with tunneling through barriers. We applied this point of view to the electron confined in a rectangular quantum corral (QC) on a noble metal surface, and obtained scanning tunneling microscopic images and a scanning tunneling spectrum consistent with experimental ones. We investigated the electron states confined in coupled QCs and obtained the coupled states constructed with bonding and anti-bonding states. Using those energy levels and wavefunctions we specified scanning tunneling microscope (STM) images and scanning tunneling spectra (STS) for the doubly and triply coupled QCs. In addition we pointed out the feature of resonant electron states associated with the same QCs at both ends of the triply coupled QCs.

Urn model for products’ shares in international trade

Science.gov (United States)

Barbier, Matthieu; Lee, D.-S.

2017-12-01

International trade fluxes evolve as countries revise their portfolios of trade products towards economic development. Accordingly products’ shares in international trade vary with time, reflecting the transfer of capital between distinct industrial sectors. Here we analyze the share of hundreds of product categories in world trade for four decades and find a scaling law obeyed by the annual variation of product share, which informs us of how capital flows and interacts over the product space. A model of stochastic transfer of capital between products based on the observed scaling relation is proposed and shown to reproduce exactly the empirical share distribution. The model allows analytic solutions as well as numerical simulations, which predict a pseudo-condensation of capital onto few product categories and when it will occur. At the individual level, our model finds certain products unpredictable, the excess or deficient growth of which with respect to the model prediction is shown to be correlated with the nature of goods.

Prevalencia de malformaciones congénitas y factores asociados en neonatos nacidos en el Hospital Vicente Corral Moscoso, Cuenca 2010

OpenAIRE

Peralta Gutiérrez, María Augusta

2011-01-01

OBJETIVO: Determinar la prevalencia de malformaciones congénitas y factores asociados en neonatos nacidos en el Hospital Vicente Corral Moscoso (HVCM) de la ciudad de Cuenca y elaborar un plan estratégico para prevención, detección y atención de malformaciones congénitas. MATERIALES Y MÉTODO: Estudio transversal, que incluyó 2385 neonatos, fueron incluidos neonatos mayores de 20 semanas de gestación, mayores de 500 gramos, vivos o muertos. se empleó la RP (IC95%) y el chi cuadrado para sig...

Projekt OK-NET-ARABLE : mahetootmiseks vajalik teave tuleb tuua praktikuteni / Airi Vetemaa

Index Scriptorium Estoniae

Vetemaa, Airi

2015-01-01

OK-NET-ARABLE, mida võiks tõlkida kui põllukultuuride kasvatuse alast maheteabe võrgustikku, on ELi teadusrahastu Horisont 2020 projekt, mille eesmärk on vahendada innovaatilist ja traditsioonilist teavet mahetootjate, nõustajate ja teadlaste vahel, suurendamaks mahepõllukultuuride produktiivsust ja kvaliteeti üle Euroopa

Effects of seasonal variability in across- and alongshore transport of anchoveta ( Engraulis ringens) larvae on model-based pre-recruitment indices off central Chile

Science.gov (United States)

Parada, Carolina; Colas, Francois; Soto-Mendoza, Samuel; Castro, Leonardo

2012-01-01

An individual-based model (IBM) of anchoveta ( Engraulis ringens) larvae was coupled to a climatological hydrodynamic (Regional Oceanic Modeling System, ROMS) model for central-southern Chile to answer the question as to whether or not across- and alongshore transport off central-southern Chile enhances retention in the spawning areas during the winter and summer reproductive periods, using model-based pre-recruitment indices (simulated transport success to nursery areas). The hydrodynamic model validation showed that ROMS captures the mean Seas Surface Temperature and Eddie Kinetic Energy observed in satellite-based data over the entire region. The IBM was used to simulate the transport of eggs and larvae from spawning zones in central Chile (Constitución, Dichato, Gulf of Arauco and Lebu-Corral) to historical nursery areas (HRZ, region between 35°S and 37°S). Model results corroborated HRZ as the most successful pre-recruitment zone (particles originated in the Dichato and Gulf of Arauco spawning areas), as well as identifying Lebu-Corral as a zone of high retention with a high associated pre-recruitment index (particles originated in the Lebu-Corral spawning zone). The highest pre-recruitment values were mainly found in winter. The Constitución and Dichato spawning zones displayed a typical summer upwelling velocity pattern, while the Gulf of Arauco in summertime showed strong offshore and alongshore velocity components. The Lebu-Corral region in winter presented important near-surface cross-shore transport towards the coast (associated with downwelling events), this might be one of the major mechanisms leading to high retention levels and a high pre-recruitment index for Lebu-Corral spawning zone. The limitations of the modeling approach are discussed and put into perspective for future work.

Do Vaccines Cause Autism? Is it OK to Skip Certain Vaccines? Get the facts

Science.gov (United States)

... Lifestyle Infant and toddler health Do vaccines cause autism? Is it OK to skip certain vaccines? Get ... their potentially serious complications. Vaccines do not cause autism. Despite much controversy on the topic, researchers haven' ...

Effect of Picibanil (OK 432) on the Scavenging Effect of Free Radicals Produced during Liver Regeneration in the Rat

OpenAIRE

Okamoto, Ko; Hamazaki, Keisuke; Iwagaki, Hiromi; Orita, Kunzo; Mori, Akitane

1995-01-01

We administered a biological response modifier Picibanil (OK-432), attenuated Streptococcus pyogenes, via the dorsal vein of the penis after 70% hepatectomy in rats, and clarified the scavenging effect of Picibanil on free radicals generated in the regenerating liver. A group of 5 rats was intravenously administered with 25 KE/kg of OK-432 after hepatectomy, while the control group was given saline after hepatectomy. Serum levels of aspartate aminotransferase and alanine aminotransferase and ...

Aproksymacja środkowej powierzchni powłok

OpenAIRE

Preweda, Edward

1997-01-01

Konstrukcjom cienkościennym stawiany jest warunek zgodności ich powierzchni środkowej z powierzchnią określoną założeniami projektowymi. Grubość powłoki uzależniona jest od panujących w niej naprężeń i najczęściej nie jest stała dla całej powłoki. W pracy przedstawiono algorytm badania kształtu powłok uwzględniający powyższe uwarunkowania. Weryfikacja algorytmu na przykładzie hiperboloidalnych chłodni jednopowłokowych wyraźnie uwidacznia różnice pomiędzy aproksymacją powierzchni zewnętrznej i...

Does HDR Pre-Processing Improve the Accuracy of 3D Models Obtained by Means of two Conventional SfM-MVS Software Packages? The Case of the Corral del Veleta Rock Glacier

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Álvaro Gómez-Gutiérrez

2015-08-01

Full Text Available The accuracy of different workflows using Structure-from-Motion and Multi-View-Stereo techniques (SfM-MVS is tested. Twelve point clouds of the Corral del Veleta rock glacier, in Spain, were produced with two different software packages (123D Catch and Agisoft Photoscan, using Low Dynamic Range images and High Dynamic Range compositions (HDR for three different years (2011, 2012 and 2014. The accuracy of the resulting point clouds was assessed using benchmark models acquired every year with a Terrestrial Laser Scanner. Three parameters were used to estimate the accuracy of each point cloud: the RMSE, the Cloud-to-Cloud distance (C2C and the Multiscale-Model-to-Model comparison (M3C2. The M3C2 mean error ranged from 0.084 m (standard deviation of 0.403 m to 1.451 m (standard deviation of 1.625 m. Agisoft Photoscan overcome 123D Catch, producing more accurate and denser point clouds in 11 out 12 cases, being this work, the first available comparison between both software packages in the literature. No significant improvement was observed using HDR pre-processing. To our knowledge, this is the first time that the geometrical accuracy of 3D models obtained using LDR and HDR compositions are compared. These findings may be of interest for researchers who wish to estimate geomorphic changes using SfM-MVS approaches.

Effect of concomitant use of immunomodulator (OK-432 and/or PSK) on advanced lung cancer (squamous cell carcinoma and adenocarcinoma) treated with radiation with combined chemotherapy

International Nuclear Information System (INIS)

Ogawa, Yasuhiro; Kimura, Shuji; Imajo, Yoshinari

1982-01-01

Between 1975 and 1979, 209 cases of primary lung cancer admitted to the department of radiology were treated with radiation with combined chemotherapy. OK-432 and/or PSK as an immunomodulator was administered to 130 of these cases, and survival curves were evaluated between the patients with OK-432 and/or PSK and those without immunomodulator. In 61 cases (squamous cell carcinoma and adenocarcinoma) in stage III (UICC, 1978), fifty percent survival period was found to be 12.5 months for 16 cases with OK-432, 13.5 months for 9 cases with OK-432 and PSK, 9.0 months for 18 cases with PSK, and 8.0 months for 18 cases without immunotherapy, respectively. (author)

Limpieza de la sala para ordeño y corrales de espera en lecherías, con uso racional del agua

OpenAIRE

Paniagua Madrigal, Wilfrido

2006-01-01

La limpieza de las salas de ordeño y corrales en los sistemas de producción de leche, tradicionalmente se han caracterizado por las grandes cantidades de agua que se utilizan. Este trabajo pretende demostrar que se puede producir leche haciendo un uso racional del recurso agua sin que ello signifique la presencia de malos olores, incidencia de mosca doméstica y pérdida de la calidad sanitaria de la leche. Los datos que se presentan en el artículo, son parte de los resultados logrados en el pr...

Effect of concomitant use of immunomodulator (OK-432 and/or PSK) on primary lung cancer (stages III, IV) treated with radiation combined with chemotherapy

International Nuclear Information System (INIS)

Kimura, S.; Ogawa, Y.; Imajo, Y.

1982-01-01

OK-432 (a lyophilized preparation of a low virulent strain, Su, of Streptococcus hemolytics (Group A) treated with penicillin G) and/or PSK (a protein-bound polysaccharide prepared from Coriolus versicolor) as an immunomodulator was administered to 209 patients of advanced lung cancer treated with radiation with combined chemotherapy. Their effects on immunological parameters and patients' survival periods were examined. Suppression of both PHA (phytohemagglutinin) skin test activities and lymphocyte blastoid transformation with PHA were reduced in the immunomodulator administered group compared with the non-administered group. Survival curves were evaluated between the patients with OK-432 and/or PSK and those without immunomodulator. It was suggested that OK-432 and/or PSK combined with radiation with combined chemotherapy was effective for the elongation of the survival period. These results indicated that the long-term administration of OK-432 and/or PSK was recommended for patients with advanced lung cancer. (author)

Percutaneous sclerotherapy of sialoceles after parotidectomy with fibrin glue, OK-432, and bleomycin.

Science.gov (United States)

Chen, Wei-liang; Zhang, Li-ping; Huang, Zhi-quan; Zhou, Bin

2013-12-01

We evaluated the curative effect of fibrin glue combined with OK-432 (streptococcal pyrogenic exotoxin A, Picibanil™) and bleomycin on 9 patients with sialoceles after parotidectomy. The primary lesions included pleomorphic adenomas in 6 cases and Warthin's tumours in 3 cases. After a sialocele had been diagnosed each patient had repeated aspirations and pressure dressings for 3-4 weeks, but these treatments failed. The patients were then treated with percutaneous sclerotherapy with the injection of fibrin glue 8-10 ml combined with OK-432 5 mg and bleomycin 15 mg. All the sialoceles disappeared completely after a single procedure in 2-3 weeks. The patients have been followed up for more than 6 months with no evidence of recurrent sialocele or injury to the facial nerve related to sclerotherapy. This simple, safe technique can be successfully used to treat sialoceles after parotidectomy. Copyright © 2013 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

Vaccination with OK-432 followed by TC-1 tumor lysate leads to significant antitumor effects.

Science.gov (United States)

Chen, I-Ju; Yen, Chih-Feng; Lin, Kun-Ju; Lee, Chyi-Long; Soong, Yung-Kuei; Lai, Chyong-Huey; Lin, Cheng-Tao

2011-07-01

Human papillomavirus (HPV) infects large numbers of women worldwide and is present in more than 99% of all cervical cancer. TC-1 cell is a cell line with high expression of E7 antigen of HPV type 16 and its cell lysate has been demonstrated as an ideal inducer of E7-specific, antitumor immunity. OK-432 (Picibanil), a penicillin-killed Streptococcus pyogenes, has been reported with potent immunomodulation properties in cancer treatment by stimulating the maturation of dendritic cells (DCs) and secretion of Th-1 type cytokines. The current study demonstrated that a protocol to immunize the C57BL/6 mice with OK-432 followed by treatment with TC-1 lysate can generate markedly increased immune responses of E7-specific CD4(+) T cells and a moderate increase of natural killer (NK) cell, as well as a satisfactorily protective and therapeutic antitumor effect by triggering the DCs to prime T cells. Depletion of lymphocyte subset in vivo suggested that the antitumor effects could be dominantly executed by CD8+ T cells and followed by NK cells, and both of these reactions were induced by the generation of robust E7-specific CD4(+) T helper cell response. These findings warrant OK-432 combination with tumor-lysate as an effective and safe vaccine in future clinical application of cervical cancer.

Percutaneous sclerotherapy of massive macrocystic lymphatic malformations of the face and neck using fibrin glue with OK-432 and bleomycin.

Science.gov (United States)

Chen, W-l; Huang, Z-q; Chai, Q; Zhang, D-m; Wang, Y-y; Wang, H-j; Wang, L; Fan, S

2011-06-01

Picibanil (OK-432) and bleomycin have been used as alternative sclerosing agents for lymphatic malformations. This study evaluated the clinical curative effect of sclerotherapy using fibrin glue combined with OK-432 and bleomycin for the treatment of macrocystic lymphatic malformations of the face and neck. Fifteen paediatric patients (6 males; 9 females, aged 13 months to 14 years) who had received percutaneous sclerotherapy for massive macrocystic lymphatic malformations of the face and neck were retrospectively reviewed. Affected regions included the neck, parotid region and parapharynx, mouth floor, face and cheek, and orbital regions. All patients showed preoperative symptoms of space-occupying lesions between 4 cm × 5 cm and 12 cm × 16 cm in size. Fibrin glue with OK-432 and bleomycin was injected under general anaesthesia. All patients received preoperative and follow-up CT scans. Outcomes were assessed by three surgeons. All patients exhibited mid-facial swelling for 3-4 weeks after surgery, but no major complications. Follow-up periods ranged from 8 to 16 months. Eight lesions were completely involuted, five were mostly involuted, and two were partially involuted. Percutaneous sclerotherapy using fibrin glue with OK-432 and bleomycin provided a simple, safe, and reliable alternative treatment for massive macrocystic lymphatic malformations of the face and neck. Copyright © 2011 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

Efficacy of in vitro sensitized cells generated by in vivo priming with OK-432 for adoptive immunotherapy of the poorly immunogenic B16-Bl6 melanoma.

Science.gov (United States)

Mukai, S; Kato, H; Kimura, S; Asai, K; Kawahito, Y; Inoue, M; Yamamura, Y; Sano, H; Sugino, S; Shu, S; Kondo, M

1996-02-01

We investigated the efficacy of the streptococcal preparation OK-432 as an adjuvant for in vivo priming in induction of sensitized cells for adoptive immunotherapy of the poorly immunogenic B16-BL6 (BL6) melanoma. C57BL/6 (B6) mice were immunized subcutaneously (s.c.) with 3 x 10(6) viable BL6 tumor cells admixed with various doses of OK-432 ranging from 1 to 100 micrograms in the foot-pad. Draining popliteal lymph nodes (LNs) were harvested 7 days after immunization and LN cells were further sensitized with irradiated tumor cells in the presence of 60-300 IU/ml of IL-2 for 11 days. These in vitro sensitized (IVS) cells (2 x 10(6)) were transferred intravenously (i.v.) to B6 mice bearing 4-day pulmonary metastases established by i.v. injection of 2-4 x 10(5) viable BL6 cells. The mice were also received intraperitoneally (i.p.) 4 x 10(4) IU/day of IL-2 for 4 days after adoptive transfer. Transfer of IVS cells from mice immunized by s.c. injection of tumor cells admixed with 10 micrograms of OK-432 significantly reduced the numbers of BL6 pulmonary metastases compared with that of control IVS' cells without the administration of OK-432 (P = 0.003). These effective IVS cells also significantly prolonged the survival of treated animals (P = 0.003). Functional IVS cells required in vitro stimulation with tumor cells. However, addition of OK-432 in the vaccine resulted in no enhancement of in vitro cytotoxicity and no characteristic change of phenotype of IVS cells. These results suggest that in vivo priming of OK-432 facilitates the sensitization of tumor-reactive T-cells. The procedure of in vivo priming with OK-432 may be beneficial in the adoptive immunotherapy of melanoma.

Comentarios a la nueva Ley Nº 14.867 que regula el engorde intensivo a corral de bovinos y bubalinos en la provincia de Buenos Aires

OpenAIRE

Noseda, Paula

2017-01-01

A fines de enero de este año 2017, entró en vigencia la Ley N° 14.867 que regula la actividad de engorde intensivo a corral de bovinos y bubalinos en la Provincia de Buenos Aires. Con este comentario se pretende evaluar las ventajas y desventajas de contar con éste nuevo régimen, considerando la normativa agroambiental marco, la posición de la doctrina y la jurisprudencia bonaerense vigente en la materia.

U Jóok'ol T'aan, "La salida del habla" U Jóok'ol T'aan, "The Coming Out of Speech"

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Hilario Chi Canul

2012-01-01

Full Text Available En este escrito pretendo desarrollar la concepción, la metodología, epistemología, la didáctica y la pedagogía que está detras de U jóok'ol t'aan, "La salida del habla", desde y con las voces de algunas madres mayas, obtenidas mediante una investigación etnográfica que forma parte de mi investigación de tesis "La vitalidad del Maaya T'aan. Estudio etnográfico de la comunicación intergeneracional de los mayas de Naranjal Poniente". Por otro lado, también examino la enseñanza escolarizada de la lengua maya, específicamente el currículo estatal que se emplea para la enseñanza de la lengua maya, y la contrapongo con la adquisición de la misma lengua en las familias para generar caminos hacia una posible interculturalización de la enseñanza de las lenguas indígenas.In this writing I am trying to develop the conception of the methodology, epistemology, didactics and the pedagogy that are standing of the u jóok'ol t'aan, "the exit of the speech", from and with the voices of some Mayan mothers, obtained by means of an ethnographic investigation that comprises of my thesis research, "La vitalidad del Maaya T'aan. Estudio etnográfico de la comunicación intergeneracional de los mayas de Naranjal Poniente". On the other hand, also I try to work and oppose the sent to school education of the Mayan language, specifically the state curriculum that is used for teaching Mayan language, with the acquisition of the same language in the families, to generate ways towards a possible interculturalization of the education of the indigenous languages.

OK-432 reduces mortality and bacterial translocation in irradiated and granulocyte-colony stimulating factor (G-CSF)-treated mice

Energy Technology Data Exchange (ETDEWEB)

Nose, Masako; Uzawa, Akiko; Ogyu, Toshiaki [National Inst. of Radiological Sciences, Chiba (Japan); Suzuki, Gen

2001-06-01

Acute radiation induces bacterial translocation from the gut, followed by systemic infection and sepsis. In order to reduce the mortality after acute whole body irradiation, it is essential to control bacterial translocation. In this study, we established a bacterial translocation assay as a sensitive method to detect minor mucosal injury by radiation. By utilizing this assay, we evaluated the adverse effects, if any, of hematopoietic reagents on the mucosal integrity in the respiratory and gastro-intestinal tracts. Bacterial translocation to the liver and spleen occurred after whole-body irradiation if the dose exceeded 6 Gy. The administration of G-CSF unexpectedly increased the bacterial translocation in 8 Gy-irradiated mice. The pharmaceutical preparation of low-virulent Streptococcus pyogenes, OK-432, significantly reduced the endotoxin levels in peripheral blood without any reduction of bacterial translocation. A combined treatment with G-CSF and OK-432 decreased bacterial translocation and prevented death. This result indicates that the early administration of G-CSF has an adverse effect on bacterial translocation, and that a combined treatment of G-CSF and OK-432 attenuates the adverse effect of G-CSF and improves the survival rate after acute irradiation. (author)

Bronze Jewellery from the Early Iron Age urn-field in Mała Kępa. An approach to casting technology

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Garbacz-Klempka A.

2017-09-01

Full Text Available This study characterizes the bronze jewellery recovered from the Lusatian culture urn-field in Mała Kępa (Chełmno land, Poland. Among many common ornaments (e.g. necklaces, rings, pins the ones giving evidence of a steppe-styled inspiration (nail earrings were also identified. With the dendritic microstructures revealed, the nail earrings prove the implementing of a lost-wax casting method, whereas some of the castings were further subjected to metalworking. The elemental composition indicates the application of two main types of bronze alloys: Cu-Sn and Cu-Sn-Pb. It has been established that the Lusatian metalworkers were familiar with re-melting the scrap bronze and made themselves capable of roasting the sulphide-rich ores.

O uso de Picibanil (OK-432 no tratamento do linfangioma de cabeça e pescoço

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Mello-Filho Francisco V.

2002-01-01

Full Text Available Introdução e Objetivo: O Linfangioma Cérvico-Facial (LCF é geralmente um tumor volumoso, envolvendo estruturas importantes da face e do pescoço. A terapia habitualmente recomendada é a retirada cirúrgica, porém, esta é geralmente seguida de seqüelas importantes, causando deformidade da região. Com o objetivo de avaliarmos uma terapêutica alternativa, analisamos a eficiência do Picibanil (OK 432 no tratamento de LCF em crianças. Forma de Estudo: Clínico retrospectivo. Material e Método: Estudo retrospectivo de seis crianças com diagnóstico de LCF tratadas com OK-432 no HCFMRP-USP no período de 1997 a 2001. Foram analisadas as seguintes características dos LCF: dimensões, tipos de cistos e volume aspirado. Avaliamos, também, o número de aplicações de OK 432 com os respectivos intervalos de tempo utilizados, sua evolução, intercorrências e o resultado final do tratamento. Resultados: Os LCFs apresentavam de oito a 15cm em seu maior diâmetro, na ocasião da primeira consulta, sendo o tipo de cisto mais freqüentemente encontrado o tipo macro cisto. O volume de liquido aspirado variou de dois a 60 ml e o número de aplicações de uma a cinco vezes em intervalos variáveis de um mês a um ano. Em todos os pacientes ocorreu regressão da massa tumoral, sendo que em três houve o desaparecimento total do LCF. A única intercorrência observada foi febre em media de 38.2º C em todos pacientes. Conclusão: O OK 432 é uma droga segura, eficaz e que pode ser utilizada como medida de primeira escolha no tratamento do LCF.

Treatment of lymphangiomas of the head and neck in children by intralesional injection of OK-432 (Picibanil).

Science.gov (United States)

Brewis, C; Pracy, J P; Albert, D M

2000-04-01

The treatments previously used for lymphangiomas of the head and neck in children-surgery and intralesional injection of sclerosants-are associated with significant morbidity. A new treatment-intralesional injection of OK-432-was used for lymphangiomas of the head and neck in 11 children. The results were total shrinkage in two, marked shrinkage in two, slight shrinkage in five and no response in two. The results were not affected by previous surgery nor by whether aspiration prior to injection was possible. There were no recurrences in those children in whom shrinkage occurred and no child had subsequent surgery following injection. The results of this series support those of previous series showing that OK-432 injection is an effective and safe treatment for lymphangiomas of the head and neck in children.

Aplikace legislativních norem u pojišťovacího zprostředkovatele OK GROUP

OpenAIRE

Kubiš, Michal

2015-01-01

Tato bakalářská práce se zabývá analýzou činností, vedoucích k bezproblémovému chodu společnosti OK GROUP a.s. v návaznosti na kontrolní činnost České národní banky. Analyzuje a podrobně popisuje kontrolní činnost jako takovou. V praktické části se zaměřím na sestavení návrhu vnitropodnikových směrnic pro zákonné fungování této firmy. This bachelor´s thesis deals with analysis of activities, which is going streight trought the smooth run of this in surance broker company OK GROUP a.s. in c...

Therapie einer postoperativ entstandenen zystischen Raumforderung mit Picibanil (OK-432): Ein Fallbericht

OpenAIRE

Schlüter, A; Weller, P; Mattheis, S; Lang, S

2014-01-01

Einleitung: Picibanil (=OK432) ist ein Lysat bestehend aus Penicillin G und mit H2O2 attenuiertem Streptococcus pyogenes. In den letzten Jahrzehnten wurde Picibanil zur Therapie von Pleuraergüssen, Lymphangiomen, Chylusfisteln, medianen Halszysten und Ranulae eingesetzt. Es verursacht eine Immunreaktion mit aseptischer Entzündung. Dies führt zu einer Zerstörung des Endothels und konsekutiv zu einer Verklebung und Schrumpfung des Zystensacks.Falldarstellung: Wir berichten über einen 40-jähri...

El Osario del Barrio Corrales del Pucará de Tilcara

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Adaro, Verónica Y.

2003-01-01

Full Text Available El Osario del Barrio Corrales, una estructura funeraria positiva del Pucará de Tilcara, contenía un conjunto entremezclado de piezas óseas humanas. Las características de este hallazgo permitieron considerar pautas culturales que llevaron a la generación de la estructura funeraria, y su vinculación respecto de los eventos de habitación y subsecuente abandono, en un contexto de activa dinámica ocupacional del Pucará, caracterizada por eventos de utilización y reutilización de los espacios, en función de la densidad poblacional. Los materiales fueron sometidos a tratamientos estandarizados de recuperación, consolidación y preservación. Mediante la cuantificación y el estudio anatómico de los hallazgos se obtienen estimadores del tamaño muestral, se consideran aspectos anátomo funcionales y patológicos, y se presenta un perfil demográfico hipotético. Los resultados permiten establecer la presencia de once individuos adultos y trece individuos inmaduros Se identificaron el sexo y las edades de muerte de adultos y subadultos. Se detectó la presencia de indicadores de estrés periódico no específico, patologías funcionales y la presencia de enfermedades infecciosas. Se concluye que el hallazgo posee características estructurales y mortuorias no registradas hasta el momento para el área. Su génesis puede estar probablemente vinculada a los eventos de reutilización mencionados. Desde el punto de vista demográfico, nuestras observaciones se ajustan a aquellos perfiles observados en poblaciones prehistóricas, caracterizadas por altas tasas de mortalidad infantil.

A density functional theory study of models for the N3 and OK1 EPR centres in diamond

International Nuclear Information System (INIS)

Etmimi, K M; Goss, J P; Briddon, P R; Gsiea, A M

2010-01-01

The defects observed in natural and synthetic diamonds provide a fingerprint of their differing growth conditions, as well as the thermal and mechanical processes they have experienced. Of the first row elements it is perhaps surprising that little evidence exists for oxygen in the form of distributed point-defects. Paramagnetic centres labelled N3 and OK1 have been assigned to two structural arrangements of pairs of substitutional nitrogen and oxygen, but there is no direct evidence for the involvement of the oxygen. In this paper we present the results of density functional simulations of N-O pairs in diamond, and review them in light of the experimental evidence. We also present analysis for other structures proposed in the literature (Ti-N, Ti-V-N, NV 2 and NVO), and show that none are particularly plausible.

Picibanil (OK-432) in the treatment of head and neck lymphangiomas in children

OpenAIRE

Rebuffini, Elena; Zuccarino, Luca; Grecchi, Emma; Carinci, Francesco; Merulla, Vittorio Emanuele

2012-01-01

Background: Picibanil (OK-432) is a lyophilized mixture of group A Streptococcus pyogenes with antineoplastic activity. Because of its capacity to produce a selective fibrosis of lymphangiomas (LMs), it has been approved by Japanese administration in 1995 for the treatment of LMs. Materials and Methods: We treated 15 children (age range: 6-60 months) affected by head and neck macrocystic LMs with intracystic injections (single dose of 0.2 mL) of Picibanil (1-3 injections). Results: Co...

Fatty acid profile and in vitro antioxidant and antibacterial activities of red grape (Vitis vinifera L. cvs. Oküzgözü and Boğazkere) Marc extracts.

Science.gov (United States)

Cibik, Bilge; Ozaydin, Zuhal; Böke, Nazli; Karabay, Ulkü; Pekmez, Murat; Arda, Nazhi; Kirmizigüla, Süheyla

2009-03-01

The marcs of two red grape (V. vinifera L.) varieties (Boğazkere and Oküzgözü), grown in eastern Anatolia (Elazig), were evaluated for their fatty acid composition, and antioxidant and antibacterial activities. The hexane extracts of both varieties were found to contain linoleic, palmitic, stearic and oleic acids by GC-MS analyses. The major fatty acid (linoleic acid) was detected relatively as 57.13% in Oküzgözü and 59.07% in Bogazkere in methylated hexane extracts. In addition, myristic and palmitoleic acids were observed in Boğazkere as minor components. The free radical (DPPH) scavenging activity of Oküzgözü was higher than that of Bogazkere. The IC50 values were calculated as 403.0 +/- 7.8 microg/mL for Oküzgozü and 552.0 +/- 23.6 microg/mL for Bogazkere. The extracts were found to be effective on the four gram (+) and four gram (-) test bacteria, but not as good as standard antibiotic, gentamycine by MIC method.

Towards a more effective model for distance education

NARCIS (Netherlands)

Koper, Rob

2014-01-01

Reference: Koper, E.J.R. (2014). Towards a more effective model for distance education. e-Learning and Education. e-Learning and Education, 10. urn:nbn:de:0009-5-40105 http://eleed.campussource.de/archive/10/4010

UV-VUV FEL program at DUKE storage ring with OK-4 optical klystron

International Nuclear Information System (INIS)

Litvinenko, V.N.; Madey, J.M.J.; Vinokurov, N.A.

1993-01-01

A 1 GeV electron storage ring dedicated for UV-VUV FEL operation is under construction at the Duke University Free Electron Laser Laboratory. The UV-VUV-FEL project, based on the collaboration of the Duke FEL Laboratory and Budker Institute for Nuclear Physics is described. The main parameters of the DFELL storage ring, of the OK-4 optical klystron, and the experimental set-up are presented. The parameters of UV-VUV FEL are given and the possible future upgrades to this system are discussed

A Case of Sublingual Ranula That Responded Successfully to Localized Injection Treatment with OK-432 after Healing from Drug Induced Hypersensitivity Syndrome

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Kunio Yoshizawa

2016-01-01

Full Text Available A ranula is a mucus retention cyst or pseudocyst caused by leakage of mucus from the sublingual gland and generally occurs in the oral floor. In addition, drug induced hypersensitivity syndrome (DIHS is a rare but well-recognized serious adverse effect characterized by fever, skin rashes, generalized lymphadenopathy, hepatitis, and hepatosplenomegaly and oral stomatitis. This paper presents the first case of successfully treated sublingual ranula with localized injection of OK-432 after healing from drug induced hypersensitivity syndrome, which has previously been unreported in the literature. We present the case of a 38-year-old Japanese woman with sublingual ranula that responded successfully to localized injection treatment with OK-432 after healing from drug induced hypersensitivity syndrome. She was affected with cutaneous myositis and interstitial lung disease when she was 26 years old. At the age 34 years, she received additional oral treatment of diaminodiphenyl-sulfone due to deterioration of the cutaneous myositis, which resulted in drug induced hypersensitivity syndrome (DIHS with severe oral stomatitis. Local injection of OK-432 to the ranula may be a very safe and useful treatment method even if the patient has a history of drug allergy and has connective tissue disease such as cutaneous myositis.

New combined therapy of radiation and local administration of OK-432 for esophageal cancer

International Nuclear Information System (INIS)

Mukai, Minoru; Morita, Shinroku; Tsunemoto, Hiroshi

1990-01-01

We devised new combination therapy of radiation and local administration of OK-432 and performed for 26 patients with esophageal cancer between March, 1987 and December, 1988 as a pilot study. The average age was 73 years. Among 26 patients, males were 20 and females were six. Patients were irradiated at the schedule of under 2 Gy/day and the dose of TDF (time, dose and fractionation factor) 100 totally. OK-432, 10KE was endoscopically administered around cancer lesion at the beginning of the radiotherapy, and two weeks later, 5KE was given in the same manner. Complete response was obtained in 20 out of 26 cases (77%) and partial response was obtained in the remaining six cases (23%). All six patients with tumor length less than five cm showed complete response. All 16 patients who could not eat food orally before treatment, became to take food enough orally after the treatment and could discharge in good condition. One year and two years survival rate of 26 patients by Kaplan Meier method were 67.4% and 47.2%, respectively. Six patients with tumor length less than five cm, are all alive without a sign of recurrence. This combination therapy will improve not only the response rate and the survival rate, but also the quality of life of patients with esophageal cancer. (author)

77 FR 57112 - Notice of Inventory Completion: U.S. Department of Defense, Army, Fort Sill Museum, Lawton, OK

Science.gov (United States)

2012-09-17

... Landmark and Museum, U.S. Army Fires Center of Excellence, Fort Sill, OK 73503, telephone (580) 442-6570... trapping, 3 metal rings, 2 metal rivets, 17 metal nails, 53 metal bracelets, 1 metal pail, 1,500 glass... A. Neel, Director, Fort Sill National Historic Landmark and Museum, U.S. Army Fires Center of...

Dzīves stila reklāma žurnālā "Cosmopolitan" (2008. gada janvāris - 2008. gada decembris)

OpenAIRE

Millere, Katrīna

2009-01-01

Bakalaura darbs “Dzīves stila reklāma žurnālā “Cosmopolitan” (2008.gada janvāris – 2008. gada decembris)” pievēršas tādai masu komunikācijas tēmai kā dzīves stila reklāma. Mūsdienu reklāmas pasaule ir tik dažāda un bagātīga ar patērētāju piesaistīšanas paņēmieniem. Tomēr ir reklāmas formāts, kas pārdod nevis preci, bet gan dzīves stilu. Patērētājs, iegādājoties kādu preci iedomājas, ka iegūst sev jaunu statusu. Tomēr vai tas tā ir? Vai arī reklāma meistarīgi spēlē ar cilvēku prātiem? Ba...

OK-432 (Picibanil) sclerotherapy for recurrent dislocation of the temporomandibular joint in elderly edentulous patients: Case reports.

Science.gov (United States)

Matsushita, Kazuhiro; Abe, Takae; Fujiwara, Toshikatsu

2007-09-01

Dislocation of the temporomandibular joint (TMJ) is a thorny problem not only for a patient but also a doctor. Especially for the elderly edentulous patients, it is very hard to treat the condition although there are many surgical and non-surgical procedures. We successfully treated it in two elderly edentulous patients by injection of OK-432 as a sclerosing agent.

Review: David Lohmann (2003. Das Bielefelder Diakonie-Management-Modell [The Bielefeld Deaconry Management Model

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Jürgen Rausch

2006-01-01

Full Text Available In six chapters, David LOHMANN makes suggestions for theological-ethical deaconry management, including a consideration of economic necessities. Through a qualitative comparison of documented sources, the author generates a theory of theological-ethical enterprise management. Following that, the author considers the theology of the deaconry in the context of TILLICH's model of believed realism and WICHERN’s theological concept of the inner mission. At the center of the examination lies a formulation of a cybernetic theory of deaconry theology. Of the available management models, the author favours the St. Galler model as the basic model of deaconry enterprise management. In doing so, the author lays out theological ground rules for the normative, strategic and operational levels of deaconry. In attempting to formulate this prospective deaconry management model through the consideration of the work of the two 20th century theologians and his own personal experience, the current needs and knowledge-base of specific deaconries are not considered. A systematic consideration of quantitative social research would have been a worthwhile supplement. In conclusion, the analysis develops a management model for deaconry enterprises that emphasizes the interdisciplinary aspects of theology and business economics. The book confirms the competitive value of a management model attuned to the theological and economic aspects of a deaconry. URN: urn:nbn:de:0114-fqs0601356

A Structural Molar Volume Model for Oxide Melts Part I: Li2O-Na2O-K2O-MgO-CaO-MnO-PbO-Al2O3-SiO2 Melts—Binary Systems

Science.gov (United States)

Thibodeau, Eric; Gheribi, Aimen E.; Jung, In-Ho

2016-04-01

A structural molar volume model was developed to accurately reproduce the molar volume of molten oxides. As the non-linearity of molar volume is related to the change in structure of molten oxides, the silicate tetrahedral Q-species, calculated from the modified quasichemical model with an optimized thermodynamic database, were used as basic structural units in the present model. Experimental molar volume data for unary and binary melts in the Li2O-Na2O-K2O-MgO-CaO-MnO-PbO-Al2O3-SiO2 system were critically evaluated. The molar volumes of unary oxide components and binary Q-species, which are model parameters of the present structural model, were determined to accurately reproduce the experimental data across the entire binary composition in a wide range of temperatures. The non-linear behavior of molar volume and thermal expansivity of binary melt depending on SiO2 content are well reproduced by the present model.

Spatial distribution and polarization of gamma-rays generated via Compton backscattering in the Duke/OK-4 storage ring FEL

CERN Document Server

Park, S H; Tornow, W; Montgomery, C

2001-01-01

Beams of nearly monochromatic gamma-rays are produced via intracavity Compton backscattering in the OK-4/Duke storage ring FEL, the high-intensity gamma-ray source (HI gamma S). Presently, HI gamma S generates gamma-ray beams with an energy tunable from 2 to 58 MeV and a maximum flux of 5x10 sup 7 gamma-rays per second. The gamma-rays are linearly polarized with a degree of polarization close to 100% (V.N. Litvinenko, et al., Predictions and expected performance for the VUV OK-5/Duke Storage Ring FEL with variable polarization, Nucl. Instr. and Meth. A, to be published in this proceeding) and they are collimated to pencil-like semi-monoenergetic beams with RMS energy spreads as low as 0.2%. The detailed theoretical and experimental studies of the gamma-ray beam quality were conducted during the last two years (S.H. Park, Thesis, Duke University, Durham, NC, USA, 2000). In this paper, we present the theoretical analysis and the experimental results on the spatial distribution and polarization of gamma-rays fro...

Spatial distribution and polarization of {gamma}-rays generated via Compton backscattering in the Duke/OK-4 storage ring FEL

Energy Technology Data Exchange (ETDEWEB)

Park, S.H. E-mail: shpark@nanum.kaeri.re.kr; Litvinenko, V.N.; Tornow, W.; Montgomery, C

2001-12-21

Beams of nearly monochromatic {gamma}-rays are produced via intracavity Compton backscattering in the OK-4/Duke storage ring FEL, the high-intensity {gamma}-ray source (HI{gamma}S). Presently, HI{gamma}S generates {gamma}-ray beams with an energy tunable from 2 to 58 MeV and a maximum flux of 5x10{sup 7} {gamma}-rays per second. The {gamma}-rays are linearly polarized with a degree of polarization close to 100% (V.N. Litvinenko, et al., Predictions and expected performance for the VUV OK-5/Duke Storage Ring FEL with variable polarization, Nucl. Instr. and Meth. A, to be published in this proceeding) and they are collimated to pencil-like semi-monoenergetic beams with RMS energy spreads as low as 0.2%. The detailed theoretical and experimental studies of the {gamma}-ray beam quality were conducted during the last two years (S.H. Park, Thesis, Duke University, Durham, NC, USA, 2000). In this paper, we present the theoretical analysis and the experimental results on the spatial distribution and polarization of {gamma}-rays from the HI{gamma}S facility.

Spatial distribution and polarization of γ-rays generated via Compton backscattering in the Duke/OK-4 storage ring FEL

International Nuclear Information System (INIS)

Park, S.H.; Litvinenko, V.N.; Tornow, W.; Montgomery, C.

2001-01-01

Beams of nearly monochromatic γ-rays are produced via intracavity Compton backscattering in the OK-4/Duke storage ring FEL, the high-intensity γ-ray source (HIγS). Presently, HIγS generates γ-ray beams with an energy tunable from 2 to 58 MeV and a maximum flux of 5x10 7 γ-rays per second. The γ-rays are linearly polarized with a degree of polarization close to 100% (V.N. Litvinenko, et al., Predictions and expected performance for the VUV OK-5/Duke Storage Ring FEL with variable polarization, Nucl. Instr. and Meth. A, to be published in this proceeding) and they are collimated to pencil-like semi-monoenergetic beams with RMS energy spreads as low as 0.2%. The detailed theoretical and experimental studies of the γ-ray beam quality were conducted during the last two years (S.H. Park, Thesis, Duke University, Durham, NC, USA, 2000). In this paper, we present the theoretical analysis and the experimental results on the spatial distribution and polarization of γ-rays from the HIγS facility

KADIN AKADEMİSYENLER: CAM TAVANLAR HÂLÂ ÇOK KALIN!

OpenAIRE

Özkaplan, Nurcan

2015-01-01

Cam tavan Feminist teorilerde, işgücü piyasasındaki dikey katmanlaşmayı işaret eder. Erkeklerle aynı işyerinde çalışan beyaz yakalı kadınların, daha çok orta ve alt düzey yönetici konumuna sıkışıp kaldığı ve Finansman müdürü, mütevelli heyeti başkanı, rektör, dekan vb. gibi üst düzey yönetici pozisyonlarının %95’den fazlasının erkekler tarafından temsil edildiği işgücü piyasalarının yaygın ve dirençli bir özelliğidir. Bu makalede, cam tavan konusundaki Feminist teorilerin kısa bir değerlendir...

Corralling Conflict: The Politics of Australian Federal Heritage Legislation Since the 1970s

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Paul Ashton

2006-05-01

Full Text Available In August 1968, conservative National Party leader Joh Bjelke-Petersen became Premier of the state of Queensland. He referred to conservationists as these 'subversives, these friends of the dirt'. A generation later, few if any Australian politicians would have publicly attacked the environment and its supporters for fear of electoral damage. After years of major environmental battles which on occasion determined the fate of some governments, the environment had crashed through into mainstream politics. Natural and cultural heritage was firmly on local, state and federal political agendas. Heritage in Australia was also, by the 1990s, a substantial, multifaceted industry. Cultural and eco tourism generated a significant proportion of the country's gross domestic product. Along side and partially in response to industry, a heritage bureaucracy had developed. The corporatisation of heritage saw the rise in the 1980s and 1990s of a new generation of heritage professionals who attempted with varying degrees of success to place heritage assessment on a quasi-scientific footing. Perhaps their greatest achievement, in terms of cultural heritage, was gaining recognition in the 1990s for the vital importance of intangible heritage. Intangible heritage, or social value, inscribes objects and sites that cannot speak for themselves with cultural and social meanings. Since the 1980s, some more radical practitioners had been working to counteract the dominance of tangible remains of the past in determining cultural significance. This victory over empiricism, however, was in some respects to prove pyrrhic. Heritage conservation, as with some other heritage practices, was by the turn of the twenty-first century institutionally confined in its ability to represent conflict. This article charts the incorporation and corralling of heritage work at the federal level in Australia through a case study of the rise and fall of the Australian Heritage Commission.

Limpieza de la sala para ordeño y corrales de espera en lecherías, con uso racional del agua

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Wilfrido Paniagua Madrigal

2006-05-01

Full Text Available La limpieza de las salas de ordeño y corrales en los sistemas de producción de leche, tradicionalmente se han caracterizado por las grandes cantidades de agua que se utilizan. Este trabajo pretende demostrar que se puede producir leche haciendo un uso racional del recurso agua sin que ello signifique la presencia de malos olores, incidencia de mosca doméstica y pérdida de la calidad sanitaria de la leche. Los datos que se presentan en el artículo, son parte de los resultados logrados en el proyecto “Manejo alternativo de lecherías integrados a sistemas agropecuarios de bajos insumos externos”, el cual se realizó en la Región Huetar Norte, en cinco fincas de productores de leche. Pretende de alguna manera contribuir con el desarrollo sostenible de los sistemas de producción de leche, al ofrecer alternativas que permitan cambiar los modelos de limpieza tradicionales por modelos que implementen sistemas de limpieza con usomás racional del agua.

After Prism & Tempora: How much monitoring is OK for CERN?

CERN Multimedia

Computer Security Team

2013-01-01

Edward Snowden’s revelations about the “Prism” and “Tempora” surveillance operations, run by the NSA in the US and GCHQ in the UK respectively, created quite a stir! Why has the witch hunt of a whistle-blower dominated newspaper headlines when there appears to have been no outcry over the fact that two countries have deeply penetrated our digital lives for so long?!   With echoes of George Orwell’s 1984, the two agencies collected a huge amount of Internet traffic, tapping into as much data per day as the LHC produces per year (see here). How much privacy are we willing to give up in order to protect ourselves against terrorist attacks? How much monitoring of our Internet activity is justified in order to feel safer? And how much monitoring is OK in the academic environment of CERN? As the world’s largest high-energy physics research lab and the home of the LHC, CERN is a target for hacktivists and cyber-attackers. CERN mu...

Autobiography and Anorexia: A Qualitative Alternative to Prochaska and DiClemente's Stages of Change Model

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Félix Díaz

2012-11-01

Full Text Available In this article, we propose a qualitative approach to the study of the ways in which people face good and poor health issues. During the last 30 years, Prochaska and DiClemente's "trans-theoretical model" (1982, 1983, 1984, 1986, 1992 has gained relevance as a model to assess disposition for change in patients. We revise the features of the model and its common techniques to assess stages of change, underlining its methodological and conceptual problems. Particularly, we discuss the paradoxes set by "pre-contemplation" as a concept; the exogenous definition of human problems in terms of institutional and clinical criteria; and the ambiguity of the model, where the purpose of accompanying and orienting the patient contrasts with the imposition of problem definitions and solution strategies. We propose a narrative analysis of autobiographies of patients as an alternative that recasts their own notions of "change," "problem," and "vital trajectory." We illustrate this possibility with the analysis of an autobiographic interview with a woman who has a history of anorexia. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1203209

Morphologic and functional alterations induced by low doses of mercuric chloride in the kidney OK cell line: ultrastructural evidence for an apoptotic mechanism of damage

International Nuclear Information System (INIS)

Carranza-Rosales, Pilar; Said-Fernandez, Salvador; Sepulveda-Saavedra, Julio; Cruz-Vega, Delia E.; Gandolfi, A. Jay

2005-01-01

Mercury produces acute renal failure in experimental animal models, but the mechanism of tubular injury has not completely been clarified. There is an increased interest in the role of apoptosis in the pathogenesis of renal diseases that result primarily from injury to renal tubular epithelial cells. However, detailed studies of morpho-functional alterations induced by mercuric chloride in kidney cell lines are scarce. This work characterizes these alterations in OK cell cultures. Morphological alterations were profiled using light microscopy, transmission electron microscopy, and confocal microscopy, as well as mitochondrial functional assays in the cells exposed to low concentrations of HgCl 2 . At concentrations of 1 and 10 μM of HgCl 2 there were no morphological or ultrastructural alterations, but the mitochondrial function (MTT assay) and intracellular ATP content was increased, especially at longer incubation times (6 and 9 h). At 15 μM HgCl 2 , both the mitochondrial activity and the endogenous ATP decreased significantly. At this concentration the OK cells rounded up, had increased number of cytoplasmic vacuoles, and detached from the cell monolayer. At 15 μM HgCl 2 ultrastructural changes were characterized by dispersion of the ribosomes, dilatation of the cisterns of the rough endoplasmic reticulum, increase of number of cytoplasmic vacuoles, chromatin condensation, invaginations of the nuclear envelope, presence of cytoplasmic inclusion bodies, and alterations in the size and morphology of mitochondria. At 15 μM HgCl 2 apoptotic signs included membrane blebbing, chromatin condensation, mitochondrial alterations, apoptotic bodies, and nuclear envelope rupture. Using confocal microscopy and the mitochondrial specific dye MitoTracker Red, it was possible to establish qualitative changes induced by mercury on the mitochondrial membrane potential after incubation of the cells for 6 and 9 h with 15 μM HgCl 2 . This effect was not observed at short times

Bütünleşik Tedarik Zinciri Ağında Tesis Yeri Seçimi için Bulanık Çok Amaçlı Programlama Modeli

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Hüseyin Ali Sarıkaya

2014-05-01

Full Text Available Geleneksel tedarik zinciri ağı tasarım problemleri genellikle tek amaçlı olarak ele alınmıştır. Ancak, tedarik zincirleri gerçek hayatta birbirleri ile çelişen amaçları olan organizasyonların meydana getirdiği karmaşık ağlardır. Bu çalışmada, piyasa taleplerinin belirsiz olduğu bütünleşik bir tedarik zinciri ağındaki birden fazla ölçülemeyen amacı gerçekleştirmek için çok ürünlü, çok aşamalı ve çok dönemli planlama modeli önerilmiştir. Tedarik zinciri planlama modeli, birbiriyle çelişen birkaç amacı doyurmak için karışık tam sayılı doğrusal olmayan programlama problemi olarak bina edilmiştir. Önerilen model iki amaç fonksiyonundan oluşmaktadır. Birincisi, tedarik zincirindeki sabit tesis açma ve işletme maliyetleri ile mesafelere bağlı olarak belirlenen taşıma maliyetlerinin en azlanmasıdır. İkincisi, Ekonomik Üretim Miktarı (EÜM modeline göre satın alma, sipariş verme, stok bulundurma ve yok satma maliyetlerinin en azlanmasıdır. Önerilen modelde, karar vericilerin kesin olmayan hedef değerlerini dahil edebilmek için bulanık hedef programlama yaklaşımı kullanılmıştır. Model, GAMS optimizasyon programı kullanılarak çözülmüştür. Çalışmada sunulan uygulama sonuçları, bulanık modelleme ve çözüm yaklaşımlarının daha gerçekçi tedarik zinciri modelleri oluşturulmasında kullanılabileceğini göstermiştir.

Flora cactológica y especies asociadas en el área natural protegida Sierra Corral de los Bandidos, Nuevo León, México Cactus list and asociated plants of the protected natural area Sierra Corral de Los Bandidos, Nuevo Leon, Mexico

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María del Pilar Carmona-Lara

2008-12-01

Full Text Available El área natural protegida (ANP Sierra Corral de los Bandidos ubicada en la sierra Madre Oriental, al noroeste de Monterrey, sufre el impacto de actividades antropológicas asociadas al matorral submontano (ganadería, agricultura, colecta y urbanismo, disminuyendo sus recursos naturales y amenazando sus especies endémicas, principalmente cactáceas. El propósito del estudio fue conocer la diversidad de cactáceas y especies asociadas en zonas de amortiguamiento y núcleo. Para ello se determinaron índices de riqueza y similitud utilizando un muestreo estratificado con cuadrantes a lo largo de transectos orientados por gradientes altitudinales según su zonificación. En total se registraron 112 taxa (30 cactáceas, 87 (24 cactáceas en zona de amortiguamiento y 80 (19 cactáceas en zona núcleo. Por su densidad, frecuencia y abundancia sobresalieron Echinocereus stramineus (Engelm. Engelm. ex F. Seitz, Cylindropuntia leptocaulis F. M. Knuth in Backeb et F. M. Knuth, Mammillaria melanocentra Poselg., Neolloydia conoidea (DC Britton et Rose, (Cactaceae; Erioneuron avenaceum (H. B et K. Tateoka, (Poaceae; Viguiera stenoloba S. F. Blake; Zexmenia hispida (Kunth A. Gray, (Asteraceae y Agave lechuguilla Torr, (Agavaceae. Existe diferencia significativa entre las poblaciones de cactus de las zonas del ANP, según Jacquard (13%, Sörensen (38% y Morisita (0.44. Ocho cactáceas (7 endémicas están registradas en algún estatus de la NOM-ECOL-059, 2001.The Sierra Corral de los Bandidos is a natural protected area located in the Sierra Madre Oriental mountain range northwest of Monterrey city. This preserve suffers the impact of human activities in the form of cattle ranching, agriculture, harvest of wild plants, and urbanism, diminishing its natural resources and threatening its endemic species, especially from the cactaceae family. The purpose of this study was to obtain information on the diversity of cacti and associated species in the buffer and

Enzymatic digestive activity and absorption efficiency in Tagelus dombeii upon Alexandrium catenella exposure

Science.gov (United States)

Fernández-Reiriz, M. J.; Navarro, J. M.; Cisternas, B. A.; Babarro, J. M. F.; Labarta, U.

2013-12-01

We analyzed absorption efficiency (AE) and digestive enzyme activity (amylase, cellulase complex, and laminarinase) of the infaunal bivalve Tagelus dombeii originating from two geographic sites, Corral-Valdivia and Melinka-Aysén, which have different long-term paralytic shellfish poisoning (PSP) exposure rates. We report the effects of past feeding history (origin) on T. dombeii exposed to a mixed diet containing the toxic dinoflagellate Alexandrium catenella and another dinoflagellate-free control diet over a 12-day period in the laboratory. Absorption efficiency values of T. dombeii individuals that experienced PSP exposure in their habitat (Melinka-Aysén) remained unchanged during exposure to toxic food in the laboratory. In contrast, T. dombeii from a non-PSP exposure field site (Corral-Valdivia) showed a significant reduction in AE with toxic exposure time. This study established that the amylase and cellulase complexes were the most important enzymes in the digestive glands of Tagelus from both sites. The temporal evolution of enzymatic activity under toxic diet was fitted to exponential (amylase and cellulase) and to a logarithmic (laminarinase) models. In all fits, we found significant effect of origin in the model parameters. At the beginning of the experiment, higher enzymatic activity was observed for clams from Corral-Valdivia. The amylase activity decreased with time exposure for individuals from Corral and increased for individuals from Melinka. Cellulase activity did not vary over time for clams from Corral, but increased for individuals from Melinka and laminarinase activity decreased over time for individuals from Corral and remained unchanged over time for Melinka. A feeding history of exposure to the dinoflagellate A. catenella was reflected in the digestive responses of both T. dombeii populations.

El patrimonio industrial minero de Corrales en Aljaraque : catalogación, propuesta de protección urbanística y modelo de difusión didáctica para la enseñanza primaria obligatoria

OpenAIRE

Molero de los Santos, María Elena

2013-01-01

Durante el año 2008, cursé los estudios en Patrimonio Histórico y Natural, a través del Màster Oficial de igual nombre con mención de calidad ANECA, ofertado por la Universidad de Huelva, La realización de estos estudios y el interés que suscitó el entorno de Corrales en Aljaraque, me llevaron a documentarme e iniciar un proceso de investigación en el que todavía hoy me encuentro inmersa. A los conocimientos adquiridos, tras la formación recibida en diferentes áreas del patrimonio, se une una...

Structure, Quaternary history, and general geology of the Corral Canyon area, Los Angeles County, California

Science.gov (United States)

Yerkes, R.F.; Wentworth, Carl M.

1965-01-01

The Corral Canyon nuclear power plant site consists of about 305 acres near the mouth of Corral Canyon in the central Santa Monica Mountains; it is located on an east-trending segment of the Pacific Coast between Point Dume and Malibu Canyon, about 28 miles due west of Los Angeles. The Santa Monica Mountains are the southwesternmost mainland part of the Transverse Ranges province, the east-trending features of which transect the otherwise relatively uniform northwesterly trend of the geomorphic and geologic features of coastal California. The south margin of the Transverse Ranges is marked by the Santa Monica fault system, which extends eastward near the 34th parallel for at least 145 miles from near Santa Cruz Island to the San Andreas fault zone. In the central Santa Monica Mountains area the Santa Monica fault system includes the Malibu Coast fault and Malibu Coast zone of deformation on the north; from the south it includes an inferred fault--the Anacapa fault--considered to follow an east-trending topographic escarpmemt on the sea floor about 5 miles south of the Malibu Coast fault. The low-lying terrain south of the fault system, including the Los Angeles basin and the largely submerged Continental Borderland offshore, are dominated by northwest-trending structural features. The Malibu Coat zone is a wide, east-trending band of asymmetrically folded, sheared, and faulted bedrock that extends for more than 20 miles along the north margin of the Santa Monica fault system west of Santa Monica. Near the north margin of the Malibu Coast zone the north-dipping, east-trending Malibu Coast fault juxtaposes unlike, in part contemporaneous sedimentary rock sections; it is inferred to be the near-surface expression of a major crustal boundary between completely unrelated basement rocks. Comparison of contemporaneous structural features and stratigraphic sections (Late Cretaceous to middle Miocene sedimentary, rocks and middle Miocene volcanic and intrusive igneous rocks

Localisation in a Growth Model with Interaction

Science.gov (United States)

Costa, M.; Menshikov, M.; Shcherbakov, V.; Vachkovskaia, M.

2018-05-01

This paper concerns the long term behaviour of a growth model describing a random sequential allocation of particles on a finite cycle graph. The model can be regarded as a reinforced urn model with graph-based interaction. It is motivated by cooperative sequential adsorption, where adsorption rates at a site depend on the configuration of existing particles in the neighbourhood of that site. Our main result is that, with probability one, the growth process will eventually localise either at a single site, or at a pair of neighbouring sites.

Comparative study of acute lateral skin damage during radio wave and laser exposure

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Dubensky V.V.

2017-09-01

Full Text Available The purpose was to study the depth and nature of the zones of thermal damage to the skin under radio wave and laser skin dissection during experiment. Material and Methods. The model of acute thermal damage was full-liner skin wounds of 20 nonlinear rats that were divided into 2 groups and operated by different methods. In the 1st group, the incisions were made by the apparatus of radio wave surgery (Surgitron DF S5, in the 2nd group the animals were operated with a laser surgical apparatus. The magnitude and structure of the lateral thermal damage was evaluated when analyzing the biopsy material. Results. During the study of experimental wounds, the extent of carbonation in the first group (operated with Surgitron DF S5 was 11.56±3.056 urn, coagulation necrosis 116.5±26.78 urn, and the hyper-thermiazone 148.42±60.171 urn. In the group of animals operated with a laser apparatus, the carbonization zone was 22.58±6.62 urn, the coagulation necrosis zone was 331.1±79.08 urn, and the hyperthermia extent was 376.2±53.27 urn. Conclusion. A comparative study of lateral skin damage in radio wave and laser skin dissection revealed a deeper thermal change in the skin and an increase in the extent of thermally altered structures under laser action: the carbonization zone was larger than for radio waves by 11.02 urn, coagulation necrosis by 214.6 urn, and the hyperthermia zone by 227.78 urn.

Treatment of lymphangiomas in children: an update of Picibanil (OK-432) sclerotherapy.

Science.gov (United States)

Greinwald, J H; Burke, D K; Sato, Y; Poust, R I; Kimura, K; Bauman, N M; Smith, R J

1999-10-01

Picibanil (OK-432) is a sclerosing agent derived from a low-virulence strain of Streptococcus pyogenes that induces regression of macrocystic lymphangiomas. This report describes a prospective, nonrandomized trial to evaluate the efficacy of Picibanil in the treatment of 13 affected children ranging in age from 1 to 94 months. On average, 4.1 fluoroscopically guided intracystic injections were performed per child, with an average total dose of 0.56 mg of Picibanil. As judged by physical examination and radiographic studies, 5 children (42%) showed a complete or substantial response, and 2 children (16%) showed an intermediate response. No response was seen in 5 children (42%), 2 of whom had massive craniofacial lymphangioma. Factors that contribute to failure with Picibanil sclerotherapy are the presence of a significant microcystic component to the lesion, massive craniofacial involvement, and previous surgical resection. Macrocystic lymphangiomas of the infratemporal fossa or cervical area have the best response to therapy.

Decision-Making under Ambiguity Is Modulated by Visual Framing, but Not by Motor vs. Non-Motor Context. Experiments and an Information-Theoretic Ambiguity Model.

Science.gov (United States)

Grau-Moya, Jordi; Ortega, Pedro A; Braun, Daniel A

2016-01-01

A number of recent studies have investigated differences in human choice behavior depending on task framing, especially comparing economic decision-making to choice behavior in equivalent sensorimotor tasks. Here we test whether decision-making under ambiguity exhibits effects of task framing in motor vs. non-motor context. In a first experiment, we designed an experience-based urn task with varying degrees of ambiguity and an equivalent motor task where subjects chose between hitting partially occluded targets. In a second experiment, we controlled for the different stimulus design in the two tasks by introducing an urn task with bar stimuli matching those in the motor task. We found ambiguity attitudes to be mainly influenced by stimulus design. In particular, we found that the same subjects tended to be ambiguity-preferring when choosing between ambiguous bar stimuli, but ambiguity-avoiding when choosing between ambiguous urn sample stimuli. In contrast, subjects' choice pattern was not affected by changing from a target hitting task to a non-motor context when keeping the stimulus design unchanged. In both tasks subjects' choice behavior was continuously modulated by the degree of ambiguity. We show that this modulation of behavior can be explained by an information-theoretic model of ambiguity that generalizes Bayes-optimal decision-making by combining Bayesian inference with robust decision-making under model uncertainty. Our results demonstrate the benefits of information-theoretic models of decision-making under varying degrees of ambiguity for a given context, but also demonstrate the sensitivity of ambiguity attitudes across contexts that theoretical models struggle to explain.

Decision-Making under Ambiguity Is Modulated by Visual Framing, but Not by Motor vs. Non-Motor Context. Experiments and an Information-Theoretic Ambiguity Model.

Directory of Open Access Journals (Sweden)

Jordi Grau-Moya

Full Text Available A number of recent studies have investigated differences in human choice behavior depending on task framing, especially comparing economic decision-making to choice behavior in equivalent sensorimotor tasks. Here we test whether decision-making under ambiguity exhibits effects of task framing in motor vs. non-motor context. In a first experiment, we designed an experience-based urn task with varying degrees of ambiguity and an equivalent motor task where subjects chose between hitting partially occluded targets. In a second experiment, we controlled for the different stimulus design in the two tasks by introducing an urn task with bar stimuli matching those in the motor task. We found ambiguity attitudes to be mainly influenced by stimulus design. In particular, we found that the same subjects tended to be ambiguity-preferring when choosing between ambiguous bar stimuli, but ambiguity-avoiding when choosing between ambiguous urn sample stimuli. In contrast, subjects' choice pattern was not affected by changing from a target hitting task to a non-motor context when keeping the stimulus design unchanged. In both tasks subjects' choice behavior was continuously modulated by the degree of ambiguity. We show that this modulation of behavior can be explained by an information-theoretic model of ambiguity that generalizes Bayes-optimal decision-making by combining Bayesian inference with robust decision-making under model uncertainty. Our results demonstrate the benefits of information-theoretic models of decision-making under varying degrees of ambiguity for a given context, but also demonstrate the sensitivity of ambiguity attitudes across contexts that theoretical models struggle to explain.

Decision-Making under Ambiguity Is Modulated by Visual Framing, but Not by Motor vs. Non-Motor Context. Experiments and an Information-Theoretic Ambiguity Model

Science.gov (United States)

Grau-Moya, Jordi; Ortega, Pedro A.; Braun, Daniel A.

2016-01-01

A number of recent studies have investigated differences in human choice behavior depending on task framing, especially comparing economic decision-making to choice behavior in equivalent sensorimotor tasks. Here we test whether decision-making under ambiguity exhibits effects of task framing in motor vs. non-motor context. In a first experiment, we designed an experience-based urn task with varying degrees of ambiguity and an equivalent motor task where subjects chose between hitting partially occluded targets. In a second experiment, we controlled for the different stimulus design in the two tasks by introducing an urn task with bar stimuli matching those in the motor task. We found ambiguity attitudes to be mainly influenced by stimulus design. In particular, we found that the same subjects tended to be ambiguity-preferring when choosing between ambiguous bar stimuli, but ambiguity-avoiding when choosing between ambiguous urn sample stimuli. In contrast, subjects’ choice pattern was not affected by changing from a target hitting task to a non-motor context when keeping the stimulus design unchanged. In both tasks subjects’ choice behavior was continuously modulated by the degree of ambiguity. We show that this modulation of behavior can be explained by an information-theoretic model of ambiguity that generalizes Bayes-optimal decision-making by combining Bayesian inference with robust decision-making under model uncertainty. Our results demonstrate the benefits of information-theoretic models of decision-making under varying degrees of ambiguity for a given context, but also demonstrate the sensitivity of ambiguity attitudes across contexts that theoretical models struggle to explain. PMID:27124723

A phase II study of cisplatin, oral administration of etoposide, OK-432 and radiation therapy for inoperable stage III non-small cell lung cancer

International Nuclear Information System (INIS)

Abe, Yoshinao; Takahashi, Jutaro; Fukuda, Hiroshi

1998-01-01

This study was designed to evaluate the feasibility and efficiency of giving cisplatin, etoposide, and OK-432 concurrently with conventional radiotherapy (RTx) for patient's with inoperable stage III, based on the TNM classification according to the International Union against Cancer staging system for lung cancer (1987) non-small cell lung cancer (NSCLC). From January 1992 to December 1994, 31 patients with cytologically or histologically confirmed stage III NSCLC were treated with RTx, to a total dose of 56-64 Gy, with concurrent daily oral administration of etoposide (25 mg) and cisplatin (20 mg) for 5 days during the third or fourth week from the start of RTx. The subcutaneous injection of 1 or 2 KE of OK-432, three times a week, for the duration of radiotherapy also started from the beginning of RTx. The number of eligible patients was 29 (26 men and 3 women). Their mean age was 66 years (range, 55-77 years). Six patients had an Eastern Cooperative Oncology Group performance status (PS) of 0; 15, 1; 8; 2. Three were stage IIIA, and 26, stage IIIB. Histologically, 2 had adenocarcinoma, 23, squamous cell carcinoma, and 4, large cell carcinoma. In 27 of the 29 patients, the RTx schedule was completed. There were no treatment-related deaths. Grade 4 toxicity (according to World Health Organisation criteria) leukopenia (700/μl) was observed in 1 patient. The response rate was 79% and the median survival was 17 months. Survival rates at 1, 2 and 3 years were 62%, 31%, and 21%, respectively. The local failure rate was 51%. The combination of cisplatin, etoposide, and OK-432, given concurrently with conventional RTx is feasible and effective for inoperable stage III NSCLC. (author)

Picibanil (OK-432) in the treatment of head and neck lymphangiomas in children.

Science.gov (United States)

Rebuffini, Elena; Zuccarino, Luca; Grecchi, Emma; Carinci, Francesco; Merulla, Vittorio Emanuele

2012-12-01

Picibanil (OK-432) is a lyophilized mixture of group A Streptococcus pyogenes with antineoplastic activity. Because of its capacity to produce a selective fibrosis of lymphangiomas (LMs), it has been approved by Japanese administration in 1995 for the treatment of LMs. We treated 15 children (age range: 6-60 months) affected by head and neck macrocystic LMs with intracystic injections (single dose of 0.2 mL) of Picibanil (1-3 injections). Complete disappearance of the lesion was noticed in eight (53.33%) cases, a marked (>50%) reduction of LMs was found five (33.33%) cases, while a moderate (Picibanil side effects included fever, local inflammation, and transitory increase of blood platelets' concentration; a single case of anemia was resolved with concentrated red blood cells transfusion. Intracystic injection of Picibanil is an effective and safe treatment for macrocystic LMs in pediatric patients and may represent the treatment of choice in such cases, especially where surgical excision is associated with the risk of functional/cosmetic side effects.

Çok Etmenli Sistemlerde NetLogo İle Karınca Kolonisi Optimizasyonu

Directory of Open Access Journals (Sweden)

Mustafa Tüker

2013-02-01

Full Text Available Çok etmenli sistemler (ÇES, karmaşık optimizasyon problemlerinin modellenmesi ve çözülmesi için etkin bir yol sunarlar. Bu çalışmada, Gezgin Satıcı Problemi (GSP'ni çözmek için ÇES ve karınca kolonileri birlikte kullanılmıştır. Sistem benzetimi, etmen tabanlı bir programlama ortamı olan NetLogo ile gerçekleştirilmiştir. Problemin modellenmesi ve benzetimi için NetLogo'nun nasıl kullanılacağı kodlarla ayrıntılı olarak açıklanmıştır. Algoritma farklı düğüm sayıları için denenmiş ve elde edilen sonuçlar tartışılmıştır.

Emission analysis of Tb3+ -and Sm3+ -ion-doped (Li2 O/Na2 O/K2 O) and (Li2 O + Na2 O/Li2 O + K2 O/K2 O + Na2 O)-modified borosilicate glasses.

Science.gov (United States)

Naveen Kumar Reddy, B; Sailaja, S; Thyagarajan, K; Jho, Young Dahl; Sudhakar Reddy, B

2018-05-01

Four series of borosilicate glasses modified by alkali oxides and doped with Tb 3+ and Sm 3+ ions were prepared using the conventional melt quenching technique, with the chemical composition 74.5B 2 O 3 + 10SiO 2 + 5MgO + R + 0.5(Tb 2 O 3 /Sm 2 O 3 ) [where R = 10(Li 2 O /Na 2 O/K 2 O) for series A and C, and R = 5(Li 2 O + Na 2 O/Li 2 O + K 2 O/K 2 O + Na 2 O) for series B and D]. The X-ray diffraction (XRD) patterns of all the prepared glasses indicate their amorphous nature. The spectroscopic properties of the prepared glasses were studied by optical absorption analysis, photoluminescence excitation (PLE) and photoluminescence (PL) analysis. A green emission corresponding to the 5 D 4 → 7 F 5 (543 nm) transition of the Tb 3+ ions was registered under excitation at 379 nm for series A and B glasses. The emission spectra of the Sm 3+ ions with the series C and D glasses showed strong reddish-orange emission at 600 nm ( 4 G 5/2 → 6 H 7/2 ) with an excitation wavelength λ exci = 404 nm ( 6 H 5/2 → 4 F 7/2 ). Furthermore, the change in the luminescence intensity with the addition of an alkali oxide and combinations of these alkali oxides to borosilicate glasses doped with Tb 3+ and Sm 3+ ions was studied to optimize the potential alkali-oxide-modified borosilicate glass. Copyright © 2017 John Wiley & Sons, Ltd.

OK432 (picibanil) efficacy in an adult with cystic cervical lymphangioma. A case report.

Science.gov (United States)

Alonso, Juan; Barbier, Luis; Alvarez, Julio; Romo, Laura; Martín, Jesús C; Arteagoitia, Iciar; Santamaría, Joseba

2005-01-01

Cervical cystic lymphangioma (CCL) is a rare and benign tumour involving congenital and cystic abnormalities derived from lymphatic vessels. The most accepted treatment continues to be surgical excision. However, when this infiltrates vital neurovascular neck structures, complete excision is difficult and if only partial, the recurrence rate is very high. The most frequently used alternative treatment is to inject sclerosants into the lesion. The use of these techniques has reported good results in children; however, there are few references thereof with regard to adults. We are reporting on a cervical cystic lymphangioma in a male aged 22, treated with an intra-lesion injection of 20 cc with 0.01 mg/cc dilution of OK-432 (picibanil) in physiological serum. Sole complications were fever and local reaction where the solution was injected. One month after treatment the lymphangioma had totally remitted and sixteen months later continues in remittance.

Context, Experience, Expectation, and Action—Towards an Empirically Grounded, General Model for Analyzing Biographical Uncertainty

Directory of Open Access Journals (Sweden)

Herwig Reiter

2010-01-01

Full Text Available The article proposes a general, empirically grounded model for analyzing biographical uncertainty. The model is based on findings from a qualitative-explorative study of transforming meanings of unemployment among young people in post-Soviet Lithuania. In a first step, the particular features of the uncertainty puzzle in post-communist youth transitions are briefly discussed. A historical event like the collapse of state socialism in Europe, similar to the recent financial and economic crisis, is a generator of uncertainty par excellence: it undermines the foundations of societies and the taken-for-grantedness of related expectations. Against this background, the case of a young woman and how she responds to the novel threat of unemployment in the transition to the world of work is introduced. Her uncertainty management in the specific time perspective of certainty production is then conceptually rephrased by distinguishing three types or levels of biographical uncertainty: knowledge, outcome, and recognition uncertainty. Biographical uncertainty, it is argued, is empirically observable through the analysis of acting and projecting at the biographical level. The final part synthesizes the empirical findings and the conceptual discussion into a stratification model of biographical uncertainty as a general tool for the biographical analysis of uncertainty phenomena. URN: urn:nbn:de:0114-fqs100120

Efecto de tres abonos orgánicos: lombricomposta, bocashi y tierra de corral en un cultivo intercalado de jitomate (Solanum lycopersicon) y pepino (Cucumis sativus) bajo invernadero en el ejido El Limón, Tepalcingo, Morelos, México

OpenAIRE

Hernández Tapia, Alejandro; Ramírez-Rivero,Libia Aidé; Corlay-Chee, Langen; Cruz Rodríguez, Juan Antonio

2015-01-01

Se evaluó una intercalación de jitomate y pepino bajo condiciones de invernadero, con un diseño de bloques completos al azar, con nueve tratamientos de abono en cuatro repeticiones (Bocashi, lombricomposta y tierra de corral con tres niveles de dosificación 0.5, 1.0 y 1.5 kg/m2).Se evaluó rendimiento y,en el caso del jitomate número de frutos dañados. Se empleó un análisis de varianza (ANOVA) y pruebas de comparación de medias (Tukey α=.05). En el caso del pepino, con el tratamiento lombri...

Impact of sophisticated fog spray models on accident analyses

International Nuclear Information System (INIS)

Roblyer, S.P.; Owzarski, P.C.

1978-01-01

The N-Reactor confinement system release dose to the public in a postulated accident is reduced by washing the confinement atmosphere with fog sprays. This allows a low pressure release of confinement atmosphere containing fission products through filters and out an elevated stack. The current accident analysis required revision of the CORRAL code and other codes such as CONTEMPT to properly model the N Reactor confinement into a system of multiple fog-sprayed compartments. In revising these codes, more sophisticated models for the fog sprays and iodine plateout were incorporated to remove some of the conservatism of steam condensing rate, fission product washout and iodine plateout than used in previous studies. The CORRAL code, which was used to describe the transport and deposition of airborne fission products in LWR containment systems for the Rasmussen Study, was revised to describe fog spray removal of molecular iodine (I 2 ) and particulates in multiple compartments for sprays having individual characteristics of on-off times, flow rates, fall heights, and drop sizes in changing containment atmospheres. During postulated accidents, the code determined the fission product removal rates internally rather than from input decontamination factors. A discussion is given of how the calculated plateout and washout rates vary with time throughout the analysis. The results of the accident analyses indicated that more credit could be given to fission product washout and plateout. An important finding was that the release of fission products to the atmosphere and adsorption of fission products on the filters were significantly lower than previous studies had indicated

Kurumsal Sürdürülebilirlik Performansının Ölçümü İçin Çok Kriterli Bir Çerçeve: Henkel Örneği

OpenAIRE

Ahmet Öztel; Mehmet Said Köse; İhsan Aytekin

2012-01-01

Kurumsal sürdürülebilirlik performans ölçümü, kurumsal sürdürülebilirliğin çevresel, sosyal ve ekonomik yönlerini ele almayı amaçlamaktadır. Bu üç boyutun tek bir boyuta indirgenmesinde sorunlar ortaya çıkmaktadır. Çok kriterli karar verme yöntemleri, bu değişkenlerin birlikte değerlendirilmesi için kullanışlı bir çerçeve sunmaktadır. Bu çalışmada, çok kriterli karar verme yöntemlerinden uzlaşık programlama (compromise programing) çerçevesi kullanılarak Henkel firmasının kurumsal sürdürülebil...

Randomized controlled study on the effect of adjuvant immunotherapy with OK-432 on malignant gliomas

International Nuclear Information System (INIS)

Shibata, Shobu; Mori, Kazuo; Moriyama, Tadayoshi; Tanaka, Keisei; Moroki, Jiro.

1985-01-01

During periods from January, 1981 to December, 1983, 51 patients (31 malignant astrocytomas, 17 glioblastomas, and others 3) were treated with radiochemotherapy using Nimustine hydrochloride, ACNU (group B) and radiochemoimmunotherapy with Picibanil, OK-432 (group A) by randomized controlled study. Group A consisted of 24 patients and group B of 27 patients. The differences in the background of the two groups were not statistically significant. Survival curves of both groups were shown by the Kaplan-Meier method. The postoperative survival rate at 1 year and 2 years were 70 % and 30 %, respectively, equal in both groups, and the differences between groups A and B were not statistically significant by the Cox-Mantel test. The side effects by group B therapy were most prominent in the bone marrow, and severe leukopenia occurred. However, group A therapy suppressed leukopenia after 2 months. Immunological parameters, such as purified protein derivative skin reaction test did not change, but streptococcal Su-polysaccharide skin reaction test became positive after group A therapy. (author)

Güneş enerjisi destekli çok fonksiyonlu trijenerasyon sisteminin termodinamik analizi

Directory of Open Access Journals (Sweden)

Önder KIZILKAN

2016-02-01

Full Text Available Bu çalışmada güneş enerjisi destekli çok fonksiyonlu bir trijenerasyon sisteminin modellemesi ve termodinamik analizleri yapılmıştır. Sistemde, gaz türbinleri için yeni bir teknoloji olan güneş kulesi vasıtasıyla gaz çevrimi ve buhar çevirimi için gerekli termal enerji sağlanmaktadır. Ayrıca, sisteme absorbsiyonlu soğutma sistemi, buhar üretim prosesi, kurutma prosesi ve kullanım sıcak suyu ısıtma prosesi entegre edilmiştir. Trijenerasyon sisteminin birinci kanun ve ikinci kanun analizleri yapılarak enerji ve ekserji verimleri tespit edilmiştir. Analizler sonucunda gaz çevrimi verimi %31, buhar çevrimi verimi %28, soğutma sisteminin performans katsayısı (COP değeri ise 0.77 olarak tespit edilmiştir. Ekserji kayıpları incelendiğinde ise en yüksek ekserji kaybının 4154 kW ile güneş kulesinde meydana geldiği tespit edilmiştir.Anahtar Kelimeler: Güneş kulesi, Trijenerasyon, Gaz çevrimi, Buhar çevrimi, Enerji, Ekserji

The version control service for ATLAS data acquisition configuration filesDAQ ; configuration ; OKS ; XML

CERN Document Server

Soloviev, Igor; The ATLAS collaboration

2012-01-01

To configure data taking session the ATLAS systems and detectors store more than 160 MBytes of data acquisition related configuration information in OKS XML files. The total number of the files exceeds 1300 and they are updated by many system experts. In the past from time to time after such updates we had experienced problems caused by XML syntax errors or inconsistent state of files from a point of view of the overall ATLAS configuration. It was not always possible to know who made a modification causing problems or how to go back to a previous version of the modified file. Few years ago a special service addressing these issues has been implemented and deployed on ATLAS Point-1. It excludes direct write access to XML files stored in a central database repository. Instead, for an update the files are copied into a user repository, validated after modifications and committed using a version control system. The system's callback updates the central repository. Also, it keeps track of all modifications providi...

One-step Conversion of Levulinic Acid to Succinic Acid Using I2/t-BuOK System: The Iodoform Reaction Revisited.

Science.gov (United States)

Kawasumi, Ryosuke; Narita, Shodai; Miyamoto, Kazunori; Tominaga, Ken-Ichi; Takita, Ryo; Uchiyama, Masanobu

2017-12-21

The iodoform reaction has long been used as a qualitative test for acetyl and/or ethanol units in organic molecules. However, its synthetic applications are quite limited. Here, we describe a tuned iodoform reaction for oxidative demethylation reaction with I 2 and t-BuOK in t-BuOH, in which in situ-generated t-BuOI serves as the chemoselective iodinating agent. This system enables one-step conversion of levulinic acid to succinic acid, a major four-carbon chemical feedstock. This oxidative demethylation is also applicable to other compounds containing an acetyl group/ethanol unit, affording the corresponding carboxylic acids in a selective manner.

Dzimtes diskurss sporta žurnālistikā: Eiropas čempionātu basketbolā reprezentāciju Latvijas interneta ziņu portālos "Delfi" un "Tvnet" analīze (2008–2013) 

OpenAIRE

Ērmiņa, Evisa

2014-01-01

Maģistra darbā „Dzimtes diskurss sporta žurnālistikā: Eiropas čempionātu basketbolā reprezentāciju Latvijas interneta ziņu portālos "Delfi" un "Tvnet" analīze (2008-2013)” ir apskatītas Latvijas vīriešu un sieviešu basketbola izlases reprezentācijas Eiropas čempionātu laikā no 2008. līdz 2013. gadam (no maija līdz oktobrim) interneta ziņu portālos „Delfi” un „Tvnet”. Darba teorētiskā daļa satur atziņas par reprezentāciju, sociālās realitātes konstruēšanu, mediju ietekmi uz realitāti un ide...

Phase formation in K2O(K2CO3)-CdO-MoO3 system

International Nuclear Information System (INIS)

Tsirenova, G.D.; Tsybikova, B.A.; Bazarova, Zh.G.; Solodovnikov, S.F.; Zolotova, E.S.

2000-01-01

Phase formation in K 2 O(K 2 CO 3 )-CdO-MoO 3 system are studied by the methods of x-ray diffraction, thermal and crystal optical analyses. Three potassium-cadmium molybdates are detected: K 4 Cd(MoO 4 ) 3 with a new structure, alluodite-like K 4-2x Cd 1+x (MoO 4 ) 3 (0.26≤x≤0.38 at 470 Deg C) and K 4 CdMo 4 O 15 of K 4 MnMo 4 O 15 type. First of them decomposes in solid phase at 580 Deg C, and others melt incongruently at 720 and 515 Deg C correspondingly. It is established that K 4-2x Cd 1+x (MoO 4 ) 3 compound undergoes phase transition of the second type in the temperature interval of 500-550 Deg C. Phase diagram of quasibinary cross section K 2 MoO 4 -CdMoO 4 is plotted [ru

Ceba a corral de vaquillas con ramas de eucaliptus, henos, grano de maíz y harina de girasol

Directory of Open Access Journals (Sweden)

A. E. Fernández

2012-01-01

Full Text Available Este trabajo se diseñó para evaluar dietas ante sequías, inundaciones u otras emergencias, se estudió la respuesta productiva y económica de doce vaquillas Angus en crecimiento, encerradas en un corral. Se establecieron tres tratamientos con dos repeticiones, bajo un diseño completamente aleatorizado y se replicaron en dos etapas: la primera, en el verano de 2007 y la segunda en el invierno de 2008. Las dietas estuvieron compuestas por: ramas de eucaliptus frescas (re a voluntad, heno de mijo (hm (1ª. etapa y de centeno (hc (2ª. etapa y un concentrado energético-proteico (c similar en ambas etapas y común a los tres tratamientos, compuesto por 1.6 kg ms grano de maíz (seco y molido cabeza.-1 día-1 y 0.9 kg ms harina de girasol, cabeza-1 día-1. T1: C + hm o hc a voluntad; T2: C + 3.5 kg tal cual de hm o hc + re a voluntad; T3: C + re a voluntad. La primera y segunda etapas duraron 61 y 62 días, respectivamente. Se midieron: el consumo de ms eucaliptus y henos (cms, eficiencia de conversión (efc, ganancias diarias de peso (gdp y el costo de producción de cada tratamiento (cp. Las efc, medios, fueron 7.98, 9.04 y 12.51 kg alimentos kg producido-1 y las gdp (verano fueron: 1.01, 0.83 y 0.53 e (invierno fueron: 0.95, 0.68 y 0.51 kg cab-1 día-1, respectivamente. Mientras que los cp, medios, fueron $0.79, 0.68 y 0.51 dólares/kilo producido-1, respectivamente. La inclusión de RE puede ser una alternativa posible ante emergencias climáticas.

Oriental medicine Kyung-Ok-Ko prevents and alleviates dehydroepiandrosterone-induced polycystic ovarian syndrome in rats.

Directory of Open Access Journals (Sweden)

Minhee Jang

Full Text Available Kyung-Ok-Ko (KOK, a traditional herbal prescription composed of Rehmannia glutinosa Liboschitz var. purpurae, Lycium chinense, Aquillaria agallocha, Poria cocos, Panax ginseng, and honey, has been widely used in traditional Oriental medicine as a vitalizing medicine or as the prescription for patients with age-associated disorders such as amnesia and stroke. However, the potential protective value of KOK for the treatment of polycystic ovarian syndrome (PCOS is largely unknown. We investigated whether pre-administration (daily from 2 hours before PCOS induction and post-administration (daily after induction of PCOS of KOK (0.5, 1.0, and 2.0 g/kg/day, p.o. could have a protective effect in a dehydroepiandrosterone (DHEA, s.c.-induced PCOS rat model. Pre-administration of KOK significantly decreased the elevated body weight and ovary weight, elevated size and number of follicular cysts, elevated level of serum glucose, and estradiol after DHEA injection. KOK reduced the elevated percentage of CD8 (+ T lymphocytes in lymph nodes, the elevated mRNA expression of CD11b and CD3 in ovaries, and infiltration of macrophages in ovarian tissue with PCOS. KOK diminished the increased mRNA expression of pro-inflammatory cytokines (IL-1β, IL-6, TNF-α, chemokines (IL-8, MCP-1, and iNOS in the ovaries, and increased the reduced mRNA expression of growth factors (EGF, TGF-β by DHEA injection. Post-administration of KOK also improved the DHEA-induced PCOS-like symptoms, generally similar to those evident from pre-administration of KOK. KOK may effectively prevent and improve DHEA-induced PCOS via anti-inflammatory action, indicating its preventive and therapeutic potential for suppressing PCOS.

Characterisation and Properties of Lithium Disilicate Glass Ceramics in the SiO2-Li2O-K2O-Al2O3 System for Dental Applications

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Naruporn Monmaturapoj

2013-01-01

Full Text Available This work proposes four different glass formulas derived from the SiO2-Li2O-K2O-Al2O3 system to investigate the effect of glass composition on their crystal formations and properties. Glass LD1 was SiO2-Li2O-K2O-Al2O3 system with the addition of P2O5 and CaF2 as nucleating agents. In Glass LD2, a slight amount of MgO was mixed in order to increase the viscosity of the melting glass. Finally, the important factor of Si : Li ratio was increased in Glasses LD3 and LD4 with compositions otherwise the same as LD1 and LD2. The results found that P2O5 and CaF2 served as a nucleating site for lithium phosphate and fluorapatite to encourage heterogenous nucleation and produce a fine-grained interlocking microstructure of lithium disilicate glass ceramics. MgO content in this system seemed to increase the viscosity of the melting glass and thermal expansion coefficient including the chemical solubility. Increasing the Si : Li ratio in glass compositions resulted in the change of the microstructure of Li2Si2O5 crystals.

An Application Of Receptor Modeling To Identify Airborne Particulate ...

African Journals Online (AJOL)

An Application Of Receptor Modeling To Identify Airborne Particulate Sources In Lagos, Nigeria. FS Olise, OK Owoade, HB Olaniyi. Abstract. There have been no clear demarcations between industrial and residential areas of Lagos with focus on industry as the major source. There is need to identify potential source types in ...

A Structural Molar Volume Model for Oxide Melts Part III: Fe Oxide-Containing Melts

Science.gov (United States)

Thibodeau, Eric; Gheribi, Aimen E.; Jung, In-Ho

2016-04-01

As part III of this series, the model is extended to iron oxide-containing melts. All available experimental data in the FeO-Fe2O3-Na2O-K2O-MgO-CaO-MnO-Al2O3-SiO2 system were critically evaluated based on the experimental condition. The variations of FeO and Fe2O3 in the melts were taken into account by using FactSage to calculate the Fe2+/Fe3+ distribution. The molar volume model with unary and binary model parameters can be used to predict the molar volume of the molten oxide of the Li2O-Na2O-K2O-MgO-CaO-MnO-PbO-FeO-Fe2O3-Al2O3-SiO2 system in the entire range of compositions, temperatures, and oxygen partial pressures from Fe saturation to 1 atm pressure.

Coarse-grained modeling of hybrid block copolymer system

Science.gov (United States)

Su, Yongrui

This thesis is comprised of three major projects of my research. In the first project, I proposed a nanoparticle model and combined it with the Theoretically Informed Coarse Grained (TICG) model for pure polymer systems and the grand canonical slip springs model developed in our group to build a new model for entangled nanocomposites. With Molecule Dynamics(MD) simulation, I studied the mechanic properties of the nanocomposites, for example the influence of nanoparticles size and volume fraction on entanglements, the diffusion of polymers and nanoparticles, and the influence of nanoparticles size and volume fraction on viscosity et al.. We found that the addition of small-size nanoparticles reduces the viscosity of the nanocomposites, which is in contrary to what Einstein predicted a century ago. However, when particle increases its size to micrometers the Einstein predictions is recovered. From our simulation, we believe that small-size nanoparticles can more effectively decrease the entanglements of nanocomposites than larger particles. The free volume effect introduced by small-size nanoparticles also helps decrease the viscosity of the whole system. In the second project, I combined the Ohta-Kawasaki (OK) model [3] and the Covariance Matrix Adaptation Evolutionary Strategy(CMA-ES) to optimize the block copolymer blends self-assembly in the hole-shrink process. The aim is to predict the optimal composition and the optimal surface energy to direct the block copolymer blends self-assembly process in the confined hole. After optimization in the OK model, we calibrated the optimal results by the more reliable TICG model and got the same morphology. By comparing different optimization process, we found that the homopolymers which are comprised of the same monomers as either block of the block copolymer can form a perfect perforated hole and might have better performance than the pure block copolymer. While homopolymers which are comprised of a third-party monomers

The Integrated Model of (Dys- Functionality: Reconstructing Patterns of Gaming as Self-Medication in Biographical Interviews with Video Game Addicts

Directory of Open Access Journals (Sweden)

Paula Bleckmann

2015-07-01

Full Text Available We aim to build a new theory of highly committed problematic video gaming based on rich qualitative data and to compare it to existing theories. To do this, we used hermeneutic analytical methods and grounded theory methodology to analyze 125 hours of recording from 42 biographical interviews, 23 of them with long-term follow-up. Participants were addicted (ex- gamers according to screening instruments, aged 16 to 44, 29 males and 13 females. The integrated (dys- functionality model shows in-game behavior of participants to be dysfunctional in that it hinders advancement in several distinguishable real-life biographical quests (for success, for belonging, and for autonomy and at the same time functional in that it matches these quests. The model integrates two seemingly irreconcilable research traditions: The addiction/disease model in medical-psychological research investigates dysfunctionality of gaming in pathological gamers. Game studies focus on functionality of in-game behavior and establish gamer typologies based on gaming motives. By adding the biographical context to game studies, but keeping the gamer's perspective, we show that gamers whose lives become dominated by gaming may know what they want and "virtually" get it, but still not "really" get it in the long term. "Compensatory" gaming does not, thus, equal unproblematic or "non-addicted" gaming. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs150387

Sampling Methods for Wallenius' and Fisher's Noncentral Hypergeometric Distributions

DEFF Research Database (Denmark)

Fog, Agner

2008-01-01

the mode, ratio-of-uniforms rejection method, and rejection by sampling in the tau domain. Methods for the multivariate distributions include: simulation of urn experiments, conditional method, Gibbs sampling, and Metropolis-Hastings sampling. These methods are useful for Monte Carlo simulation of models...... of biased sampling and models of evolution and for calculating moments and quantiles of the distributions.......Several methods for generating variates with univariate and multivariate Wallenius' and Fisher's noncentral hypergeometric distributions are developed. Methods for the univariate distributions include: simulation of urn experiments, inversion by binary search, inversion by chop-down search from...

Efficacy of dendritic cells matured early with OK-432 (Picibanil), prostaglandin E2, and interferon-alpha as a vaccine for a hormone refractory prostate cancer cell line.

Science.gov (United States)

Yoo, Changhee; Do, Hyun-Ah; Jeong, In Gab; Park, Hongzoo; Hwang, Jung-Jin; Hong, Jun Hyuk; Cho, Jin Seon; Choo, Myong-Soo; Ahn, Hanjong; Kim, Choung-Soo

2010-09-01

Dendritic cells (DCs) are potent antigen-presenting cells. OK432 (Picibanil) was introduced as a potent stimulator of DC maturation in combination with prostaglandin-E(2) and interferon-alpha. We compared the efficacy of a DC-prostate cancer vaccine using early-mature DCs stimulated with OK432, PGE2 and INF-alpha (OPA) with that of vaccines using other methods. On days 3 or 7 of DC culture, TNF-alpha (T), TNF-alpha and LPS (TL) or OPA were employed as maturation stimulators. DU145 cells subjected to heat stress were hybridized with mature DCs using polyethyleneglycol. T cells were sensitized by the hybrids, and their proliferative and cytokine secretion activities and cytotoxicity were measured. The yields of early-mature DCs were higher, compared to yields at the conventional maturation time (P<0.05). In the early maturation setting, the mean fusion ratios, calculated from the fraction of dual-positive cells, were 13.3%, 18.6%, and 39.9%, respectively (P=0.051) in the T only, TL, and OPA-treated groups. The function of cytotoxic T cells, which were sensitized with the hybrids containing DCs matured early with OPA, was superior to that using other methods. The antitumor effects of DC-DU145 hybrids generated with DCs subjected to early maturation with the OPA may be superior to that of the hybrids using conventional maturation methods.

Sclerotherapy with picibanil (OK-432) for congenital lymphatic malformation in the head and neck.

Science.gov (United States)

Sung, M W; Lee, D W; Kim, D Y; Lee, S J; Hwang, C H; Park, S W; Kim, K H

2001-08-01

Congenital lymphatic malformations of the head and neck (LMHN) present special challenges to the otolaryngologist-head and neck surgeon. Recently, a number of sclerotherapy trials have shown promising results. In this study, we present our experiences with picibanil (OK-432) sclerotherapy for this lesion. Retrospectively review. We retrospectively reviewed 21 patients who have undergone sclerotherapy with picibanil for LMHN. Satisfactory response with complete or nearly complete shrinkage of the lesions was observed in 15 cases after repeated sclerotherapy (average, two times). We did not observe any significant morbidity or complications in the patients treated with picibanil. Reduction in size of the mass was achieved in weeks to months. Some of the patients who had not had any other previous treatment showed remarkable reductions in size even after the first therapy. When we used picibanil sclerotherapy as a primary treatment for the LMHN, most of our patients showed satisfactory results regardless of the size or location of the lesions. Given with our experience and the reports that failure of picibanil sclerotherapy does not hinder subsequent surgical salvage procedures, we recommend trying picibanil sclerotherapy as a primary treatment for the LMHN and performing surgical excision as a secondary modality if the response to the sclerotherapy is not satisfactory.

Anti-platelet and anti-thrombotic effect of a traditional herbal medicine Kyung-Ok-Ko.

Science.gov (United States)

Kim, Tae-Ho; Lee, Kyoung Mee; Hong, Nam Doo; Jung, Yi-Sook

2016-02-03

Kyung-Ok-Ko (KOK), a traditional herbal prescription, contains six main ingredients; Rehmannia glutinosa var. purpurae, Lycium chinense, Aquillaria agallocha, Poria cocos, Panax ginseng, and honey. KOK has been widely taken as a traditional oriental medicine for improving blood circulation or age-related symptoms, such as dementia and stroke. However, the effect of KOK on platelet activity has not been clarified. To evaluate the effect of KOK on platelet function, we evaluated its effect on functional markers of platelet activation such as aggregation and shape change. As a mechanism study for the effect of KOK, we examined its effect on granule secretion, intracellular Ca(2+) increase, and PLCγ and Akt activation. To investigate the effect of orally administered KOK (0.5, 1, 2 g/kg), we examined its ex vivo effect on platelet aggregation in rat, and its in vivo anti-thrombotic effect in mice thromboembolism model. Furthermore, the effect of KOK on bleeding time was examined to estimate its potential side effect. KOK (0.3, 1, 3, 10 mg/ml) inhibited collagen-induced platelet aggregation and shape change in rat platelets in a concentration-dependent manner. The mechanism for the anti-platelet effect of KOK seems to involve the inhibition of ATP release, intracellular Ca(2+) elevation, and the phosphorylation of PLCγ and Akt. In rat ex vivo study, KOK (2 g/kg, p.o. for 1 day, and 0.5, 1, 2 g/kg, p.o. for 7 days) also had significant inhibitory effects on collagen-induced platelet aggregation. In addition, KOK showed a significant protective effect against thrombosis attack in mice. The prolongation of bleeding time by KOK was much less than that by ASA, suggesting a beneficial potential of KOK than ASA in view of side effect. These findings suggest that KOK elicits remarkable anti-platelet and anti-thrombotic effects with less side effect of bleeding, and therefore, it may have a therapeutic potential for the prevention of platelet-associated cardiovascular diseases

Efficacy of Dendritic Cells Matured Early with OK-432 (Picibanil®), Prostaglandin E2, and Interferon-α as a Vaccine for a Hormone Refractory Prostate Cancer Cell Line

Science.gov (United States)

Yoo, Changhee; Do, Hyun-Ah; Jeong, In Gab; Park, Hongzoo; Hwang, Jung-Jin; Hong, Jun Hyuk; Cho, Jin Seon; Choo, Myong-Soo; Ahn, Hanjong

2010-01-01

Dendritic cells (DCs) are potent antigen-presenting cells. OK432 (Picibanil®) was introduced as a potent stimulator of DC maturation in combination with prostaglandin-E2 and interferon-α. We compared the efficacy of a DC-prostate cancer vaccine using early-mature DCs stimulated with OK432, PGE2 and INF-α (OPA) with that of vaccines using other methods. On days 3 or 7 of DC culture, TNF-α (T), TNF-α and LPS (TL) or OPA were employed as maturation stimulators. DU145 cells subjected to heat stress were hybridized with mature DCs using polyethyleneglycol. T cells were sensitized by the hybrids, and their proliferative and cytokine secretion activities and cytotoxicity were measured. The yields of early-mature DCs were higher, compared to yields at the conventional maturation time (P<0.05). In the early maturation setting, the mean fusion ratios, calculated from the fraction of dual-positive cells, were 13.3%, 18.6%, and 39.9%, respectively (P=0.051) in the T only, TL, and OPA-treated groups. The function of cytotoxic T cells, which were sensitized with the hybrids containing DCs matured early with OPA, was superior to that using other methods. The antitumor effects of DC-DU145 hybrids generated with DCs subjected to early maturation with the OPA may be superior to that of the hybrids using conventional maturation methods. PMID:20808670

Review Essay: Argument is War, Love is a Journey, and Qualitative Research Needs a Pair of Glasses

Directory of Open Access Journals (Sweden)

Rudolf Schmitt

2004-05-01

Full Text Available LAKOFF and JOHNSON argue that common metaphorical words imply cognitive models, which they call "metaphorical concepts." They extend the definition of metaphor beyond classical definitions. Metaphorical concepts grasp patterns of meaning and methods of metaphor analysis have been derived from this approach as tools for interpreting qualitative data. The book reviewed was the first publication of the so-called "cognitive linguistic" school. It can still be strongly recommended for qualitative researchers today, although some definitions have changed. URN: urn:nbn:de:0114-fqs0402190

Local Delivery System of Immune Modulating Drug for Unresectable Adenocarcinoma: In Vitro Experimental Study and In Vivo Animal Study

International Nuclear Information System (INIS)

Lee, Don Haeng; Kang, Sung-Gwon; Jeong, Seok; Yoon, Chang Jin; Choi, Jung-Ah; Byun, Ju Nam; Park, Jae Hyung; Lee, Kyu Back

2006-01-01

The purpose of the study was to evaluate the efficacy and safety of a developed drug delivery system containing OK-432 through in vitro and animal study. An OK-432-impregnated polycarbonate/polyurethane stent membrane was used to develop a drug delivery system (DDS) enabling the locoregional release of OK-432. Polyethyleneglycol was used as a detergent and porosity generator. The stability of OK-432 in solvent, releasing kinetics of drug, and cytotoxicity of the DDS were evaluated. OK-432-impregnated DDS was implanted in mice in which a human adenocarcinoma cell line was injected and grown in their back. Flow cytometry and enzyme-linked immunosorbent assay were used for quantifying the amount of drug. OK-432 exposed to phosphate-buffered saline and OK-432 exposed to N,N-dimethylacetamide showed similar results on dot graphs and histograms. However, OK-432 exposed to tetrahydrofurane showed different dot graphs and histograms, which means that the antigenicity of the drug was changed. The release rate of OK-432 was maintained at a constant level for 6 weeks. The local delivery of OK-432 was found to have an antitumor effect on a human adenocarcinoma cell line in an animal study, but no effect on this cell line in in vitro cell culture. Histologic examination showed minimal inflammatory reaction in surrounding tissue. Our study shows that local treatment using this OK-432 release system is safe and effective in reducing adenocarcinoma in a mouse model

Membrane Compartmentalization Reducing the Mobility of Lipids and Proteins within a Model Plasma Membrane.

Science.gov (United States)

Koldsø, Heidi; Reddy, Tyler; Fowler, Philip W; Duncan, Anna L; Sansom, Mark S P

2016-09-01

The cytoskeleton underlying cell membranes may influence the dynamic organization of proteins and lipids within the bilayer by immobilizing certain transmembrane (TM) proteins and forming corrals within the membrane. Here, we present coarse-grained resolution simulations of a biologically realistic membrane model of asymmetrically organized lipids and TM proteins. We determine the effects of a model of cytoskeletal immobilization of selected membrane proteins using long time scale coarse-grained molecular dynamics simulations. By introducing compartments with varying degrees of restraints within the membrane models, we are able to reveal how compartmentalization caused by cytoskeletal immobilization leads to reduced and anomalous diffusional mobility of both proteins and lipids. This in turn results in a reduced rate of protein dimerization within the membrane and of hopping of membrane proteins between compartments. These simulations provide a molecular realization of hierarchical models often invoked to explain single-molecule imaging studies of membrane proteins.

Pilsoniskās žurnalistikas principi un realizācija: Latvijas interneta mediju prakses analīze

OpenAIRE

Žernakovs, Nikolajs

2012-01-01

Bakalaura darba tēma ir “Pilsoniskās žurnālistikas principi un realizācija: Latvijas interneta mediju prakses analīze”. Attīstoties jaunajām tehnoloģijām paplašinās lietotāju iespējas iesaistīties žurnālistikā, protams neprofesionālā, tāda parādība tika nosaukta par pilsonisko žurnālistiku. Darba pētniecības problēma ir tāda, ka pilosniskās žurnālistikas principi mūsdienās ir vāji izpētīti, bet cilvēki kuri grib profesionāli nodarboties ar civilo žurnālistiku nezin, kurus principus viņiem ja...

Hydroacoustic Studies Using HydroCAM - Station-centric Integration of Models and Observations. Quarterly Report No. 5 October - December 2003

International Nuclear Information System (INIS)

Upton, Zachary M.; Pulli, Jay J.

2004-01-01

OAK-B135 Quarterly Technical Report summarizing BBN's support of the DOE/NNSA GNEM program. This report details BBN's efforts to improve the modeling of explosions and other events underwater and their propagation to hydroacoustic sensor networks. OK to release, no restriction on copyright

Vaccination with NY-ESO-1 overlapping peptides mixed with Picibanil OK-432 and montanide ISA-51 in patients with cancers expressing the NY-ESO-1 antigen.

Science.gov (United States)

Wada, Hisashi; Isobe, Midori; Kakimi, Kazuhiro; Mizote, Yu; Eikawa, Shingo; Sato, Eiichi; Takigawa, Nagio; Kiura, Katsuyuki; Tsuji, Kazuhide; Iwatsuki, Keiji; Yamasaki, Makoto; Miyata, Hiroshi; Matsushita, Hirokazu; Udono, Heiichiro; Seto, Yasuyuki; Yamada, Kazuhiro; Nishikawa, Hiroyoshi; Pan, Linda; Venhaus, Ralph; Oka, Mikio; Doki, Yuichiro; Nakayama, Eiichi

2014-01-01

We conducted a clinical trial of an NY-ESO-1 cancer vaccine using 4 synthetic overlapping long peptides (OLP; peptides #1, 79-108; #2, 100-129; #3, 121-150; and #4, 142-173) that include a highly immunogenic region of the NY-ESO-1 molecule. Nine patients were immunized with 0.25 mg each of three 30-mer and a 32-mer long NY-ESO-1 OLP mixed with 0.2 KE Picibanil OK-432 and 1.25 mL Montanide ISA-51. The primary endpoints of this study were safety and NY-ESO-1 immune responses. Five to 18 injections of the NY-ESO-1 OLP vaccine were well tolerated. Vaccine-related adverse events observed were fever and injection site reaction (grade 1 and 2). Two patients showed stable disease after vaccination. An NY-ESO-1-specific humoral immune response was observed in all patients and an antibody against peptide #3 (121-150) was detected firstly and strongly after vaccination. NY-ESO-1 CD4 and CD8 T-cell responses were elicited in these patients and their epitopes were identified. Using a multifunctional cytokine assay, the number of single or double cytokine-producing cells was increased in NY-ESO-1-specific CD4 and CD8 T cells after vaccination. Multiple cytokine-producing cells were observed in PD-1 (-) and PD-1 (+) CD4 T cells. In conclusion, our study indicated that the NY-ESO-1 OLP vaccine mixed with Picibanil OK-432 and Montanide ISA-51 was well tolerated and elicited NY-ESO-1-specific humoral and CD4 and CD8 T-cell responses in immunized patients.

Validation of a prediction model that allows direct comparison of the Oxford Knee Score and American Knee Society clinical rating system.

Science.gov (United States)

Maempel, J F; Clement, N D; Brenkel, I J; Walmsley, P J

2015-04-01

This study demonstrates a significant correlation between the American Knee Society (AKS) Clinical Rating System and the Oxford Knee Score (OKS) and provides a validated prediction tool to estimate score conversion. A total of 1022 patients were prospectively clinically assessed five years after TKR and completed AKS assessments and an OKS questionnaire. Multivariate regression analysis demonstrated significant correlations between OKS and the AKS knee and function scores but a stronger correlation (r = 0.68, p Society of Bone & Joint Surgery.

Review: Carlos Kölbl (2004. Geschichtsbewußtsein im Jugendalter. Grundzüge einer Entwicklungspsychologie historischer Sinnbildung [Historical Consciousness in Adolescence. Groundwork for a Psychology of the Development of Historical Perceptiveness

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Wilhelm Schwendemann

2008-05-01

Full Text Available This book contains an empirical study of adolescents' historical perceptiveness and thus offers evidence contrary to the common stereotype that adolescents possess little, if any, consciousness of the past. A range of perception-forming models can be constructed and these can collectively be seen to represent a modern and postmodern historical consciousness. Using the methods of Grounded Theory, the author presents the reader with new perspectives on documented group interviews from the perspective of developmental/psychological hermeneutics according to WYGOTSKI and also takes into account adolescents' historical self-portraits. URN: urn:nbn:de:0114-fqs0802320

Selection of a Geostatistical Method to Interpolate Soil Properties of the State Crop Testing Fields using Attributes of a Digital Terrain Model

Science.gov (United States)

Sahabiev, I. A.; Ryazanov, S. S.; Kolcova, T. G.; Grigoryan, B. R.

2018-03-01

The three most common techniques to interpolate soil properties at a field scale—ordinary kriging (OK), regression kriging with multiple linear regression drift model (RK + MLR), and regression kriging with principal component regression drift model (RK + PCR)—were examined. The results of the performed study were compiled into an algorithm of choosing the most appropriate soil mapping technique. Relief attributes were used as the auxiliary variables. When spatial dependence of a target variable was strong, the OK method showed more accurate interpolation results, and the inclusion of the auxiliary data resulted in an insignificant improvement in prediction accuracy. According to the algorithm, the RK + PCR method effectively eliminates multicollinearity of explanatory variables. However, if the number of predictors is less than ten, the probability of multicollinearity is reduced, and application of the PCR becomes irrational. In that case, the multiple linear regression should be used instead.

Bacterial population solitary waves can defeat rings of funnels

International Nuclear Information System (INIS)

Morris, Ryan J; Phan, Trung V; Austin, Robert H; Black, Matthew; Bos, Julia A; Lin, Ke-Chih; Kevrekidis, Ioannis G

2017-01-01

We have constructed a microfabricated circular corral for bacteria made of rings of concentric funnels which channel motile bacteria outwards via non-hydrodynamic interactions with the funnel walls. Initially bacteria do move rapidly outwards to the periphery of the corral. At the edge, nano-slits allow for the transport of nutrients into the device while keeping the bacteria from escaping. After a period of time in which the bacteria increase their cell density in this perimeter region, they are then able to defeat the physical constrains of the funnels by launching back-propagating collective waves. We present the basic data and some nonlinear modeling which can explain how bacterial population waves propagate through a physical funnel, and discuss possible biological implications. (paper)

A non-destructive spectroscopic study of the decoration of archaeological pottery: from matt-painted bichrome ceramic sherds (southern Italy, VIII-VII B.C.) to an intact Etruscan cinerary urn

Science.gov (United States)

Bruni, Silvia; Guglielmi, Vittoria; Della Foglia, Elena; Castoldi, Marina; Bagnasco Gianni, Giovanna

2018-02-01

A study is presented based on the use of entirely non-destructive spectroscopic techniques to analyze the chemical composition of the painted surface layer of archaeological pottery. This study aims to define both the raw materials and the working technology of ancient potters. Energy-dispersive X-ray analysis, micro-Raman spectroscopy, visible and near infrared (NIR) diffuse reflection spectroscopy and external reflection Fourier-transform infrared (FTIR) spectroscopy were applied to matt-painted bichrome pottery sherds (VIII-VII century B.C.) from the site of Incoronata near Metaponto in southern Italy. Two different raw materials, ochre and iron-rich clay, were recognized for the red decoration, while the dark areas resulted to have been obtained by the so-called manganese black technique. In any case, it was demonstrated that the decoration was applied before firing, in spite of its sometimes grainy aspect that could suggest a post-firing application. For the samples with a more sophisticated decorative pattern a red/black/white polychromy was recognized, as the lighter areas correspond to an ;intentional white; obtained by the firing of a calcium-rich clay. Reflection spectroscopy in the visible-NIR and mid-IR as well as micro-Raman spectroscopy were then employed to characterize the decoration of an intact ceramic urn from the Etruscan town of Chiusi, evidencing a post-firing painting based on the use of red ochre, carbon black and lime, possibly imitating the ;fresco; technique used in wall paintings.

Emotionality Modulates the Effect of Chronic Stress on Feeding Behaviour in Birds

Science.gov (United States)

Favreau-Peigné, Angélique; Calandreau, Ludovic; Constantin, Paul; Gaultier, Bernard; Bertin, Aline; Arnould, Cécile; Laurence, Agathe; Richard-Yris, Marie-Annick; Houdelier, Cécilia; Lumineau, Sophie; Boissy, Alain; Leterrier, Christine

2014-01-01

Chronic stress is a long-lasting negative emotional state that induces negative consequences on animals’ psycho-physiological state. This study aimed at assessing whether unpredictable and repeated negative stimuli (URNS) influence feeding behaviour in quail. Sixty-four quail were exposed to URNS from day 17 to 40, while 64 quail were undisturbed. Two lines divergently selected on their inherent emotionality were used to assess the effect of genetic factors on the sensitivity to URNS. All quail were submitted to a sequential feeding procedure (using two diets of different energetic values) which placed them in a contrasting situation. Behavioural tests were performed to assess the emotional reactivity of the two lines. Results confirmed that differences exist between them and that their emotional reactivity was enhanced by URNS. Diet preferences, motivation and daily intake were also measured. URNS did not change the preferences for the hypercaloric diet compared to the hypocaloric diet in choice tests, but they reduced daily intakes in both lines. Motivations for each diet were differently affected by URNS: they decreased the motivation to eat the hypercaloric diet in quail selected for their low inherent fearfulness whereas they increased the motivation to eat the hypocaloric diet in quail selected for their high inherent fearfulness, which suggested a devaluation process in the former and a compensatory behaviour in the later. Growth was furthermore reduced and laying delayed by URNS in both lines. In conclusion, the exposure to URNS induced interesting changes in feeding behaviour added with an increase in emotional reactivity and an alteration of production parameters. This confirms that both lines of quail experienced a chronic stress state. However differences in feed motivation and emotional reactivity between lines under chronic stress suggested that they experienced different emotional state and use different ways to cope with it depending on their

Emotionality modulates the effect of chronic stress on feeding behaviour in birds.

Directory of Open Access Journals (Sweden)

Angélique Favreau-Peigné

Full Text Available Chronic stress is a long-lasting negative emotional state that induces negative consequences on animals' psycho-physiological state. This study aimed at assessing whether unpredictable and repeated negative stimuli (URNS influence feeding behaviour in quail. Sixty-four quail were exposed to URNS from day 17 to 40, while 64 quail were undisturbed. Two lines divergently selected on their inherent emotionality were used to assess the effect of genetic factors on the sensitivity to URNS. All quail were submitted to a sequential feeding procedure (using two diets of different energetic values which placed them in a contrasting situation. Behavioural tests were performed to assess the emotional reactivity of the two lines. Results confirmed that differences exist between them and that their emotional reactivity was enhanced by URNS. Diet preferences, motivation and daily intake were also measured. URNS did not change the preferences for the hypercaloric diet compared to the hypocaloric diet in choice tests, but they reduced daily intakes in both lines. Motivations for each diet were differently affected by URNS: they decreased the motivation to eat the hypercaloric diet in quail selected for their low inherent fearfulness whereas they increased the motivation to eat the hypocaloric diet in quail selected for their high inherent fearfulness, which suggested a devaluation process in the former and a compensatory behaviour in the later. Growth was furthermore reduced and laying delayed by URNS in both lines. In conclusion, the exposure to URNS induced interesting changes in feeding behaviour added with an increase in emotional reactivity and an alteration of production parameters. This confirms that both lines of quail experienced a chronic stress state. However differences in feed motivation and emotional reactivity between lines under chronic stress suggested that they experienced different emotional state and use different ways to cope with it

Applying model predictive control to power system frequency control

OpenAIRE

Ersdal, AM; Imsland, L; Cecilio, IM; Fabozzi, D; Thornhill, NF

2013-01-01

16.07.14 KB Ok to add accepted version to Spiral Model predictive control (MPC) is investigated as a control method which may offer advantages in frequency control of power systems than the control methods applied today, especially in presence of increased renewable energy penetration. The MPC includes constraints on both generation amount and generation rate of change, and it is tested on a one-area system. The proposed MPC is tested against a conventional proportional-integral (PI) cont...

Review: Helmut Kromrey (2006. Empirische Sozialforschung. Modelle und Methoden der standardisierten Datenerhebung und Datenauswertung [Social Research Methods. Models and Methods of Standardized Data Collection and Data Analysis

Directory of Open Access Journals (Sweden)

Udo Kuckartz

2008-01-01

Full Text Available In the new edition of his textbook, KROMREY outlines the basic principles of "traditional" empirical social research. The 650 pages of the book address the foundations of scientific theory and methods within empirical research. There are also extensive explanations of the most important methods of data collection (content analysis, observation, survey and of statistical analyses of data. This book would be a very suitable textbook for introductory university courses in the methods of empirical social research. The text includes many examples and is written in a very understandable style. Qualitative research methods are only mentioned marginally in the "Alternative Research Paradigms" section. URN: urn:nbn:de:0114-fqs0801240

Evaluation of spatial and spatiotemporal estimation methods in simulation of precipitation variability patterns

Science.gov (United States)

Bayat, Bardia; Zahraie, Banafsheh; Taghavi, Farahnaz; Nasseri, Mohsen

2013-08-01

Identification of spatial and spatiotemporal precipitation variations plays an important role in different hydrological applications such as missing data estimation. In this paper, the results of Bayesian maximum entropy (BME) and ordinary kriging (OK) are compared for modeling spatial and spatiotemporal variations of annual precipitation with and without incorporating elevation variations. The study area of this research is Namak Lake watershed located in the central part of Iran with an area of approximately 90,000 km2. The BME and OK methods have been used to model the spatial and spatiotemporal variations of precipitation in this watershed, and their performances have been evaluated using cross-validation statistics. The results of the case study have shown the superiority of BME over OK in both spatial and spatiotemporal modes. The results have shown that BME estimates are less biased and more accurate than OK. The improvements in the BME estimates are mostly related to incorporating hard and soft data in the estimation process, which resulted in more detailed and reliable results. Estimation error variance for BME results is less than OK estimations in the study area in both spatial and spatiotemporal modes.

Effect of Temperature on Film Thickness of Two Types of Commonly used Luting Cements.

Science.gov (United States)

Kumar, M Praveen; Priyadarshini, Reddy; Kumar, Yasangi M; Priya, K Shanthi; Chunchuvyshnavi, Chunchuvyshnavi; Yerrapragada, Harika

2017-12-01

The aim of this study is to evaluate the effect of temperature change on film thickness of both types of cements. Totally, 60 samples were prepared with 10 in each subgroup, thus comprising 30 in each group. Materials tested were glass ionomer cement (GIC) type I and zinc phosphate type I. Samples were manipulated with manufacturer's instructions and tested according to American Dental Association (ADA) guidelines. The mean values of film thickness were recorded for both groups I and II. In intragroup comparison of group 1, subgroup III (26.560 ± 0.489 urn) was found to have the highest film thickness followed by subgroup II (24.182 ± 0.576 urn) and the lowest in subgroup I (20.209 ± 0.493 urn). In intragroup comparison of group II, the film thickness recorded in subgroup III (25.215 ± 0.661 urn) was the highest followed by subgroup II (21.471 ± 0.771 urn) and the least in subgroup I (17.951 ± 0.654 urn; p film thickness than group I (23.650 ± 0.271). The results were found to be statistically significant (p film thickness. Zinc phosphate has less film thickness than GIC. Zinc phosphate should be preferred over GIC in clinical practice, and more stress should be given in mechanical preparation of crowns for better retentive quality of prosthesis.

SRTM Anaglyph: Corral de Piedra, Argentina

Science.gov (United States)

2001-01-01

Volcanism and erosion are prominently seen in this view of the eastern flank of the Andes Mountains taken by Shuttle Radar Topography Mission (SRTM). The area is southeast of San Martin de Los Andes, Argentina. Eroded peaks up to 2,210-meter-high (7,260-foot) are seen on the west (left), but much of the scene consists of lava plateaus that slope gently eastward. These lava flows were most likely derived from volcanic sources in the high mountains. However, younger and more localized volcanic activity is evident in the topographic data as a cone surrounding oval-shaped flow near the center of the scene.The plateaus are extensively eroded by the Rio Limay (bottom of the image) and the Rio Collon Cura and its tributaries (upper half). The larger stream channels have reached a stable level and are now cutting broad valleys. Few terraces between the levels of the high plateaus and lower valleys (bottom center and upper right of the volcanic cone) indicate that stream erosion had once temporarily reached a higher stable level before eroding down to its current level. In general, depositional surfaces like lava flows are progressively younger with increasing elevation, while erosional surfaces are progressively younger with decreasing elevation.This anaglyph was produced by first shading a preliminary SRTM elevation model. The stereoscopic effect was then created by generating two differing perspectives, one for each eye. When viewed through special glasses, the result is a vertically exaggerated view of the Earth's surface in its full three dimensions. Anaglyph glasses cover the left eye with a red filter and cover the right eye with a blue filter.Elevation data used in this image was acquired by the Shuttle Radar Topography Mission (SRTM) aboard the Space Shuttle Endeavour, launched on Feb. 11, 2000. SRTM used the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) that flew twice on the Space Shuttle

Defining Professional Communication Skills for Malaysian Gradu­ates: Looking at trustworthiness

OpenAIRE

Ahmad-Tajuddin, Azza J.

2014-01-01

It is part of ATLAS.ti User Conference 2013 : Fostering Dialog on Qualitative Methods Editor: Susanne Friese Berlin: Universitätsverlag der TU Berlin, 2014 ISBN 978-3-7983-2692-7 (composite publication) URN urn:nbn:de:kobv:83-opus4-51577 [http://nbn-resolving.de/urn:nbn:de:kobv:83-opus4-51577] Lincoln and Guba (1985) posit that trustworthiness of a qualitative research study is important to evaluate its worth. The use of data analysis software like AT...

Comparison of european computer codes relative to the aerosol behavior in PWR containment buildings during severe core damage accidents

International Nuclear Information System (INIS)

Fermandjian, J.; Beonio-Brocchieri, F.

1986-09-01

The present study concerns a comparative exercise, performed within the framework of the Commission of the European Communities, of the computer codes used in reactor safety in order to assess their capability of realistically describing the aerosol behavior in PWR reactor containment buildings during severe accidents. The codes included in the present study are the following: AEROSIM-M, AEROSOLS/Bl, CORRAL-2, NAUA Mod5. In AEROSIM-M, AEROSOLS/Bl and NAUA Mod5, the integro-differential equation for the evolution of the particle mass distribution is approximated by a set of coupled first order differential equations. To this end, the particle distribution function is replaced by a number of discrete monodisperse fractions. The CORRAL-2 has an essentially empirical basis (processes not explicitely modelled, but their net effects accounted for). The physical processes taken into account in the codes are shown finally

A simple magnetic model for intermetallics of rare earths: application to PrAl2

International Nuclear Information System (INIS)

Ranke, P.J. von; Palermo, L.; Silva, X.A. da.

1990-01-01

A simplified description of crystal field for rare earth ion systems, taking in account the first two energy levels is presented. The Hamiltonian is constructed using wave functions of these levels and, the equation of magnetic state is derived. The model is applied to PrAl 2 using experimental data of magnetization versus temperature. The parameters of magnetic behaviour at T = OK and T = T c are analysed. (M.C.K.)

Use of clearance rate in Choromytilus chorus (Bivalvia: Mytilidae as a non-destructive biomarker of aquatic pollution El uso de la tasa de aclaramiento en Choromytilus chorus (Bivalvia: Mytilidae como biomarcador no destructivo de la polución acuática

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BEATRIZ TORO

2003-06-01

Full Text Available Reduction in clearance rate was observed in the mussel Choromytilus chorus in relation to the degree of environmental pollution. Three sampling sites included the polluted San Vicente Bay, middling polluted Corral Bay, and weakly polluted Yaldad Bay in southern Chile. Pollution levels were estimated by quantitative analysis of polynuclear aromatic hydrocarbons (PAHs in mussel tissue from the three sites. Mussels from San Vicente showed lowest clearance rates and highest PAHs levels in both spring 1998 and summer 1999. Populations from Corral and Yaldad showed generally low levels of PAHs, so the mussels from Yaldad showed the highest rates of clearance in comparison to Corral and San Vicente populations. The significant negative relationship (P Se observó un deterioro de la tasa de aclaramiento en Choromytilus chorus de acuerdo al grado de polución ambiental. Se incluyeron tres sitios de muestreos, la bahía de San Vicente muy contaminada, la bahía de Corral con una polución intermedia y la bahía de Yaldad, al sur de Chile, con una baja contaminación. Los niveles de polución fueron estimados por análisis cuantitativos de hidrocarburos aromáticos polinucleares (HAPs en el tejido de los choros zapatos de los tres sitios de muestreo. Los choros zapatos de San Vicente mostraron la menor tasa de aclaramiento y altos niveles de HAPs, tanto en la primavera de 1998 como en el verano de 1999. Las poblaciones de Corral y Yaldad mostraron en general bajos niveles de HAPs, en tanto que los ejemplares de Yaldad presentaron altas tasas de aclaramiento en comparación con las poblaciones de Corral y San Vicente. La relación negativa significativa (P < 0,001 entre la polución en el tejido de los choros zapatos y sus tasas de aclaramiento, argumenta la utilidad del método como un biomarcador no destructivo para evaluar el impacto ambiental de la polución en las especies marinas

Integrated Stable Isotope - Reactive Transport Model Approach for Assessment of Chlorinated Solvent Degradation

Science.gov (United States)

2016-06-16

WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) University of Oklahoma, 100 E. Boyd St., SEC 810 Norman , OK 73019-2115 8...Deep Plume. The green diamonds indicate wells where either VC or ethene The Unit B aquitard is entirely eroded in some areas and leakage from...western section of the Deep Plume ( green symbols) are consistent with the RD model that also successfully simulated the data from the Shallow Plume. On

U.S. Navy Marine Climatic Atlas of the World. Volume 5. South Pacific Ocean. (Revised 1979)

Science.gov (United States)

1979-10-01

5 50S 81 03W 3.5 4.6 Corral, Bah a Corral ---------------. 39 52 7326W 3.2 4.0 4,3 Palta ------------------------------ 50 Ss 81 (7W 3.8 4.9...17 168 45E 3.6 5.2 3.3 Palta ---------------------------- 5 81 07W 3.8 4.9 2.4 Tlara- ------------------------4 35 8117W 4,0 5.2 2.6 Jaluit Atoll (SE

Mycotic skin lesions in an adult reindeer caused by Debaryomyces bansenii. A case report

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Claes Rehbinder

1994-12-01

Full Text Available This report apparently is the first to describe candidosis in reindeer. It is imperative that reindeer kept in corrals during winter and spring for supplementary feeding, are provided clean, dry conditions and that strict hygenic measures are followed. If reindeer on the other hand are kept in dirty, wet and muddy corrals, among other things, skin lesions due to fungal infections may possibly appear rather frequently.

Protein Polymerization into Fibrils from the Viewpoint of Nucleation Theory.

Science.gov (United States)

Kashchiev, Dimo

2015-11-17

The assembly of various proteins into fibrillar aggregates is an important phenomenon with wide implications ranging from human disease to nanoscience. Using general kinetic results of nucleation theory, we analyze the polymerization of protein into linear or helical fibrils in the framework of the Oosawa-Kasai (OK) model. We show that while within the original OK model of linear polymerization the process does not involve nucleation, within a modified OK model it is nucleation-mediated. Expressions are derived for the size of the fibril nucleus, the work for fibril formation, the nucleation barrier, the equilibrium and stationary fibril size distributions, and the stationary fibril nucleation rate. Under otherwise equal conditions, this rate decreases considerably when the short (subnucleus) fibrils lose monomers much more frequently than the long (supernucleus) fibrils, a feature that should be born in mind when designing a strategy for stymying or stimulating fibril nucleation. The obtained dependence of the nucleation rate on the concentration of monomeric protein is convenient for experimental verification and for use in rate equations accounting for nucleation-mediated fibril formation. The analysis and the results obtained for linear fibrils are fully applicable to helical fibrils whose formation is describable by a simplified OK model. Copyright © 2015 Biophysical Society. Published by Elsevier Inc. All rights reserved.

Mouse genetic model for clinical and immunological heterogeneity of leishmaniasis

Czech Academy of Sciences Publication Activity Database

Lipoldová, Marie; Svobodová, M.; Havelková, Helena; Krulová, Magdalena; Badalová, Jana; Nohýnková, E.; Hart, A. A. M.; Schlegel, David; Volf, P.; Demant, P.

2002-01-01

Roč. 54, č. 3 (2002), s. 174-183 ISSN 0093-7711 R&D Projects: GA MZd NM28; GA ČR GA310/00/0760; GA MŠk OK 394 Grant - others:Howard Hughes Medical Institute(US) HHMI55000323; WHO(XX) TDR I.D. 970772; EC(XE) ERBI-C15-CT98-0317; EC(XE) BIO-4-CT98-0445 Institutional research plan: CEZ:AV0Z5052915 Keywords : Leishmaniasis * mouse model * complex disease Subject RIV: EC - Immunology Impact factor: 2.475, year: 2002

Efeitos da climatização do curral de espera na produção de leite de vacas holandesas Effects of the climatization of the corral of wait on milk production of holstein cows

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Iran J.O. da Silva

2002-09-01

Full Text Available O presente estudo foi conduzido com o objetivo de avaliar os efeitos da climatização de ambientes em condições de pré-ordenha na produção de leite. O experimento foi realizado na fazenda experimental do Instituto de Zootecnia, em Nova Odessa, SP, durante doze dias consecutivos do verão de 1999. Foram analisados os efeitos do sistema de resfriamento evaporativo (SRE, por nebulização, no curral de espera. Utilizaram-se doze animais da raça holandesa, divididos em dois grupos de seis animais, onde apenas o segundo grupo foi submetido ao sistema de climatização. Os dados ambientais foram registrados no horário das ordenhas, ou seja, às 7 e 15 h. Para avaliação dos dados ambientais utilizaram-se os índices de conforto térmico: índice de temperatura de globo (WBGT, índice de temperatura e umidade (THI e índice de carga térmica radiante (CTR. As respostas fisiológicas, como freqüência cardíaca e respiratória, temperatura retal e produção de leite também foram consideradas variáveis de resposta. Conclui-se que o efeito do resfriamento do ambiente é mais significativo no horário da segunda ordenha (15 h, quando comparado ao da primeira (7 h, melhorando as condições de conforto térmico no curral de espera, refletindo em um aumento de 7,28% na produção de leite, além de promover redução na frequência respiratória e cardíaca.This work was carried out to evaluate the effect of the climatization of environments in daily pay-milking conditions. The experiment was carried out in the experimental farm of the Institute of Zootecnia, in Nova Odessa, SP, during twelve consecutive days of the summer. The effects of the system of evaporative cooling (SRE, by fogging in the wait corral and milking room were analyzed. Twelve Holstein cows were divided in two groups, where only the second group had passed climatization. Data environment were recorded at 7:00 am and 3:00 pm. For evaluation of the ambient data, index of thermal

AÇIK VE UZAKTAN EĞİTİM SİSTEMİ SEÇİMİ İÇİN ÇOK ÖLÇÜTLÜ BİR KARAR VERME YAKLAŞIMININ KULLANILMASI

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Zehra KAMIŞLI ÖZTÜRK

2014-02-01

Full Text Available Bugün, dünya çapında çeşitli açık ve uzaktan eğitim (ODL sistemleri bulunmaktadır. Bu noktada, yaşam boyu öğrenme kapsamında kariyer yolundaki yeteneklerini geliştirmek isteyen bir öğrenen için bir ODL programını nasıl seçeceği önemli bir soru haline gelmektedir. Bu ise birbirine bağlı ölçütlerden oluşan karmaşık bir karar problemidir. Analitik Serim Süreci (ANP , bu bağlılıkları ele alan çok ölçütlü bir karar verme yöntemidir. ANP’deki serimler en iyi kararı vermek için hem nitel hem de nicel tüm faktör ve ölçütleri içermektedir. Bu çalışmada, ODL sistemlerini etkileyen ölçütleri araştırmak ve önceliklendirmek ile öğrenenlere bir ODL programı seçiminde yardımcı olmak amacıyla bir ANP modeli kurulmuştur. Çalışma sonucunda, lisans programları en çok tercih edilen ODL programı olmuştur. Ayrıca önerilen ANP modeli, her bir program türünün yürütülmesi için hangi ölçüt ve/veya ölçütlere dikkat edilmesi konusunda da uzaktan eğitim kurumlarına yardımcı olacaktır. Bu nedenle bu çalışma, ODL politikası geliştirme açısından da kurumlara destek verecektir.

Effect of a Traditional Herbal Prescription, Kyung-Ok-Ko, on Male Mouse Spermatogenic Ability after Heat-Induced Damage

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Deok-Sang Hwang

2015-01-01

Full Text Available Kyung-Ok-Ko (KOK, a well-known traditional Korean medicinal formula, has long been used to invigorate the essential qi. This use of KOK may be associated with reproductive ability as a more modern concept. The protective effect of KOK was evaluated against deterioration of testicular function induced by heat exposure in male mice. Male fertility was disrupted by scrotal heat stress at 43°C for 5 weeks. KOK (0.25, 0.50, and 2.00 g/kg/day was administered orally at 3 h after the stress. To evaluate the protective effect of KOK, body weight, testicular weight, sperm count, sperm motility, and histopathological changes in the testes were evaluated. KOK-treated mice significantly recovered their general health, as evidenced by body weight. KOK-treated mice also showed significantly higher testes weights, sperm counts, and sperm motility than did the heat stress group. KOK-treated mice significantly recovered the morphological appearance of the seminiferous tubules and seminiferous epithelium. Furthermore, KOK-treated mice significantly increased antioxidant enzyme activities and reduced the protein expressions of apoptosis in the testes. KOK significantly protects against heat-induced damage to testicular function in male mice by inhibiting oxidative stress and apoptosis, indicating that KOK may be an effective agent for treatment of heat-induced male infertility.

Response of the rare biosphere to environmental stressors in a highly diverse ecosystem (Zodletone spring, OK, USA).

Science.gov (United States)

Coveley, Suzanne; Elshahed, Mostafa S; Youssef, Noha H

2015-01-01

Within highly diverse ecosystems, the majority of bacterial taxa are present in low abundance as members of the rare biosphere. The rationale for the occurrence and maintenance of the rare biosphere, and the putative ecological role(s) and dynamics of its members within a specific ecosystem is currently debated. We hypothesized that in highly diverse ecosystems, a fraction of the rare biosphere acts as a backup system that readily responds to environmental disturbances. We tested this hypothesis by subjecting sediments from Zodletone spring, a sulfide- and sulfur-rich spring in Southwestern OK, to incremental levels of salinity (1, 2, 3, 4, and 10% NaCl), or temperature (28°, 30°, 32°, and 70 °C), and traced the trajectories of rare members of the community in response to these manipulations using 16S rRNA gene analysis. Our results indicate that multiple rare bacterial taxa are promoted from rare to abundant members of the community following such manipulations and that, in general, the magnitude of such recruitment is directly proportional to the severity of the applied manipulation. Rare members that are phylogenetically distinct from abundant taxa in the original sample (unique rare biosphere) played a more important role in the microbial community response to environmental disturbances, compared to rare members that are phylogenetically similar to abundant taxa in the original sample (non-unique rare biosphere). The results emphasize the dynamic nature of the rare biosphere, and highlight its complexity and non-monolithic nature.

Journal of Biosciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

t.v Supervision and Inspection Center for Food Products (Shanghai), Shanghai 200233, People's Republic of China; Department of Microbiology and Microbial Engineering, School of Life Science, Fudan Urn.versit.v, Shanghai 200433, People s Republic of China; Department of Laparoscopic Surgery, Shandong Urn.versity ...

Statistical projection effects in a hydrodynamic pilot-wave system

Science.gov (United States)

Sáenz, Pedro J.; Cristea-Platon, Tudor; Bush, John W. M.

2018-03-01

Millimetric liquid droplets can walk across the surface of a vibrating fluid bath, self-propelled through a resonant interaction with their own guiding or `pilot' wave fields. These walking droplets, or `walkers', exhibit several features previously thought to be peculiar to the microscopic, quantum realm. In particular, walkers confined to circular corrals manifest a wave-like statistical behaviour reminiscent of that of electrons in quantum corrals. Here we demonstrate that localized topological inhomogeneities in an elliptical corral may lead to resonant projection effects in the walker's statistics similar to those reported in quantum corrals. Specifically, we show that a submerged circular well may drive the walker to excite specific eigenmodes in the bath that result in drastic changes in the particle's statistical behaviour. The well tends to attract the walker, leading to a local peak in the walker's position histogram. By placing the well at one of the foci, a mode with maxima near the foci is preferentially excited, leading to a projection effect in the walker's position histogram towards the empty focus, an effect strongly reminiscent of the quantum mirage. Finally, we demonstrate that the mean pilot-wave field has the same form as the histogram describing the walker's statistics.

You're OK, I'm OK

Science.gov (United States)

Kelleher, Joanne

2016-01-01

The author looks through Albert Bandura's self-efficacy lens onto the effects it likely has on school principals' effectiveness. Self-efficacy should be viewed as a principal's belief in his or her capabilities to structure a particular course of action in order to produce desired outcomes. Principal self-efficacy has been linked with effective…

Dose rate estimates and spatial interpolation maps of outdoor gamma dose rate with geostatistical methods; A case study from Artvin, Turkey

International Nuclear Information System (INIS)

Yeşilkanat, Cafer Mert; Kobya, Yaşar; Taşkin, Halim; Çevik, Uğur

2015-01-01

In this study, compliance of geostatistical estimation methods is compared to ensure investigation and imaging natural Fon radiation using the minimum number of data. Artvin province, which has a quite hilly terrain and wide variety of soil and located in the north–east of Turkey, is selected as the study area. Outdoor gamma dose rate (OGDR), which is an important determinant of environmental radioactivity level, is measured in 204 stations. Spatial structure of OGDR is determined by anisotropic, isotropic and residual variograms. Ordinary kriging (OK) and universal kriging (UK) interpolation estimations were calculated with the help of model parameters obtained from these variograms. In OK, although calculations are made based on positions of points where samples are taken, in the UK technique, general soil groups and altitude values directly affecting OGDR are included in the calculations. When two methods are evaluated based on their performances, it has been determined that UK model (r = 0.88, p < 0.001) gives quite better results than OK model (r = 0.64, p < 0.001). In addition, as a result of the maps created at the end of the study, it was illustrated that local changes are better reflected by UK method compared to OK method and its error variance is found to be lower. - Highlights: • The spatial dispersion of gamma dose rates in Artvin, which possesses one of the roughest lands in Turkey were studied. • The performance of different Geostatistic methods (OK and UK methods) for dispersion of gamma dose rates were compared. • Estimation values were calculated for non-sampling points by using the geostatistical model, the results were mapped. • The general radiological structure was determined in much less time with lower costs compared to experimental methods. • When theoretical methods are evaluated, it was obtained that UK gives more descriptive results compared to OK.

Knee awareness and functionality after simultaneous bilateral vs unilateral total knee arthroplasty

DEFF Research Database (Denmark)

Latifi, Roshan; Thomsen, Morten Grove; Kallemose, Thomas

2016-01-01

AIM: To investigate knee awareness and functional outcomes in patients treated with simultaneous bilateral vs unilateral total knee arthroplasty (TKA). METHODS: Through a database search, we identified 210 patients who had undergone unilateral TKA (UTKA) and 65 patients who had undergone......-surgical treatments were failed, thus preoperatively the patients had poor functionality. All patients were asked to complete Forgotten Joint Score (FJS) and Oxford Knee Score (OKS) questionnaires. The patients were matched according to age, gender, year of surgery, Kellgren-Lawrence score and pre- and postoperative...... overall knee alignment. The FJS and OKS questionnaire results of the two groups were then compared. RESULTS: A mixed-effects model was used to analyze differences between SBTKA and UTKA. OKS: The mean difference in the OKS between the patients who had undergone SBTKA and those who had undergone UTKA was 1...

Proceedings (Mathematical Sciences) SUBJECT INDEX

Indian Academy of Sciences (India)

Some BMO estimates for vector-valued multilinear singular integral operators ... polynomials in several variables. 117. Conformal metric ... class of urn models. 493. G-bundles. On Harder–Narasimhan reductions for. Higgs principal bundles. 127. Gel'fand space. A note on generalized characters. 437. Gel'fand transform.

Planificación estratégica en la gestión administrativa de la secretaría de obras públicas-GPAO, para optimizar la operatividad del equipo caminero.

OpenAIRE

Aguilar Toro, Jorge Iván

2017-01-01

In Latin America, the processes to develop management models are constantly evolving. CORRALES (2006) The concept of model has several associations and connotations. The first and most important is that the word model is associated with the concept of system (p. 5). In Ecuador we are already immersed and penetrated in these models defined in many areas and is taken over by SENPLADES as a product of the management of this unit have been built the national development plans 2009-2013 and 201320...

Source characteristics of the Fairview, OK, earthquake sequence and its relationship to industrial activities

Science.gov (United States)

Yeck, W. L.; Weingarten, M.; Benz, H.; McNamara, D. E.; Herrmann, R. B.; Rubinstein, J. L.; Earle, P. S.; Bergman, E.

2016-12-01

We characterize the spatio-temporal patterns of seismicity surrounding the February 13, 2016, Mw 5.1 Fairview, Oklahoma earthquake. This earthquake sequence accounts for the largest moment release in the central and eastern US since the November 06, 2011 Mw 5.6 Prague, OK earthquake sequence. To improve the location accuracy of the sequence and measure near-source ground motions, the United States Geological Survey (USGS) deployed eight seismometers and accelerometers in the epicentral region. With the added depth control from these stations, we show that earthquakes primarily occur in the Precambrian basement, at depths of 6-10 km below sea level. The Mw 5.1 mainshock, the largest event in the cluster, locates near the base of the seismicity. Relocated aftershocks delineate a partially unmapped, 14-km-long fault segment that strikes approximately N40°E, partially bridging the gap between previously mapped basement faults to the southwest and northeast. Gas production and hydraulic fracking data from the region show no evidence that either of these activities correlates spatio-temporally with the Fairview sequence. Instead, we suggest that a series of high-rate, Arbuckle injection wells (> 300,000 bbls/month) 8-25 km northeast of this sequence pressurized the reservoir in the far field. Regional injection into the Arbuckle formation increased 7-fold in the 24 months before the initiation of the sequence with some wells operating at rates greater than 1 million barrels per month. Seismicity in the proximity of the high-rate wells is diffuse whilst the energetic Fairview sequence occurs more than 15 km from this region. Our observations point to the critical role pre-existing geologic structures play in the occurrence of large induced earthquakes. This study demonstrates the need for a better understanding of the role of far-field pressurization. High-quality data sets such as this facilitate the USGS mission to improve earthquake hazard identification, especially

Finansal Varlıkları Fiyatlama Modelinin Analizi: Varsayımlar, Bulgular ve Hakkındaki Eleştiriler(An Analysis of Capital Asset Pricing Model: Assumptions, Arguments and Critics

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Hakan Bilir

2016-03-01

Full Text Available Yatırım fırsatlarının değerlendirilmesi süreci beklene getiri ve riskin ölçümüne bağlıdır. Finansal Varlıkları Fiyatlama Modeli (CAPM, çok uzun yıllardır modern finans teorisinin temel taşlarından bir tanesini oluşturmaktadır. Model, varlıkların beklenen getirisi ve sistematik riski arasındaki basit doğrusal ilişkiyi ortaya koymaktadır. Model halen, sermaye maliyetinin hesaplanması, portföy yönetiminin performansının ölçülmesi ve yatırımların değerlendirilmesi amacıyla kullanılmaktadır. CAPM’in çekiciliği, riskin ve beklenen getiri ve risk arasındaki ilişkinin ölçümlenmesi konusundaki güçlü tahmin yeteneğinden gelmektedir. Bununla birlikte modelin bu yeteneği 30 yılı aşkın bir süredir akademisyenler ve uygulamacılar tarafından sorgulanmaktadır. Tartışmalar büyük ölçüde ampirik düzeyde gerçekleştirilmektedir. CAPM’in ampirik düzeydeki problemleri, çok sayıda basitleştirilmiş varsayımı içermesi nedeniyle teorik hatalardır. Çok sayıdaki gerçekçi olmayan varsayımlar modeli pratik olarak kullanışsız hale getirmektedir. Model ile ilgili temel eleştiriler ise risksiz faiz oranı, pazar portföyü ve beta katsayı üzerinde yoğunlaşmaktadır.

Relevamiento de vectores de la Enfermedad de Chagas en peridomicilios del área rural del Departamento Ayacucho, San Luis, Argentina

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Diego I. CHARTIER

2007-01-01

Full Text Available Debido a la importancia de las poblaciones peridomésticas en los procesos de reinfestación de las viviendas, el objetivo de este trabajo fue evaluar la presencia de triatominos en peridomicilios de la comuna de San Francisco del Monte de Oro, Dpto. Ayacucho, San Luis, Argentina. Se evaluó la presencia de triatominos en 18 peridomicilios entre los meses de Octubre a Marzo (2003/2004, para cada anexo se analizó: tipo de construcción, hospedador y número de triatominos. Los triatominos capturados fueron determinados taxonómicamente y se analizó su infectividad. El 98,3 % de los triatominos pertenecieron a la especie Triatoma infestans (Klug. El 79,3 % de los anexos evaluados fueron positivos. Los índices de infestación para corrales y gallineros fueron de 94,4? % y 54,5? %, respectivamente. No se encontraron insectos infectados con Trypanosoma cruzi (Chagas. Los corrales se diferenciaron en: pirca, empalizada y troncos apilados horizontalmente. En cuanto al número de triatominos, sólo se halló diferencia significativa entre los corrales de pirca y empalizada, siendo el primero mayor (p< 0,05. Los corrales de pirca parecen ser los más aptos para refugios de los triatominos, probablemente debido a la gran cantidad de espacios vacíos que ofrece y a una mayor dificultad para el control químico.

Review: Jens Brockmeier (2015. Beyond the Archive: Memory, Narrative, and the Autobiographical Process

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Lucas Bietti

2016-08-01

Full Text Available Jens BROCKMEIER's new book proposes a very provocative aim for memory studies: "[T]o radically re-think our very idea of memory and challenge the notions of remembering and forgetting that we have taken for granted" (p.vii. The main target for the author's critique is the archival model of memory. In order to support his approach, the author provides empirical evidence from the neurosciences, social sciences, and humanities. "Beyond the Archive" represents an innovative contribution to the field of memory studies. It brings together disparate disciplinary fields in a novel and sophisticated fashion with a clear goal in mind: to propose a new model for the analysis of autobiographical remembering. BROCKMEIER's book is a true exercise of multidisciplinary research in action, which is much needed in the current climate of psychological and neuroscientific reductionism in the sciences of memory. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs160338

Combination and Integration of Qualitative and Quantitative Analysis

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Philipp Mayring

2001-02-01

Full Text Available In this paper, I am going to outline ways of combining qualitative and quantitative steps of analysis on five levels. On the technical level, programs for the computer-aided analysis of qualitative data offer various combinations. Where the data are concerned, the employment of categories (for instance by using qualitative content analysis allows for combining qualitative and quantitative forms of data analysis. On the individual level, the creation of types and the inductive generalisation of cases allow for proceeding from individual case material to quantitative generalisations. As for research design, different models can be distinguished (preliminary study, generalisation, elaboration, triangulation which combine qualitative and quantitative steps of analysis. Where the logic of research is concerned, it can be shown that an extended process model which combined qualitative and quantitative research can be appropriate and thus lead to an integration of the two approaches. URN: urn:nbn:de:0114-fqs010162

Comment on the Thorsten Berndt's Review Essay: "To Go to the Body." Advances in Phenomenological-sociological Identity Theory, published in FQS 4(3

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Robert Gugutzer

2004-01-01

Full Text Available In this Comment I praise Thorsten BERNDT's review of "To Go to the Body." At the same time I "defend" my identity model, connecting identity and to have a body ("Körper" / being a body ("Leib", in relation to the following five points: 1 identity research in the social sciences neglects the body as a fundamental entity of identity development; 2 MEAD's identity concept has a social cognitive bias; 3 interactionist identity theories need a phenomenological addition of "to have a body"/"being a body," because all interactions are bodily; 4 GOFFMAN talked explicitly about the body, but he never developed an identity theory; 5 gender identity development is as a matter of course seen as based on experiences of difference/diversity. URN: urn:nbn:de:0114-fqs040147

Corrales de piedra, campos abiertos y pampas de camaruco: Memorias de relacionalidad en la meseta central de Chubut Stone yards, open fields and sacred places: Memories of relatedness in the Chubut´s central plateau

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Ana Ramos

2008-12-01

Full Text Available La "cuestión indígena" como política de estado en Argentina ha estado acompañada por la elaboración académica de mapas étnicos. Las definiciones hegemónicas de estas entidades han presupuesto generalmente algún elemento "esencial" como, por ejemplo, fenotipos, uso de una lengua, o la aglutinación en torno a linajes consanguíneos. A partir de las reformulaciones de las teorías del parentesco desde el modelo heurístico de las sociedades de casas y las teorías sobre la relacionalidad proponemos una aproximación a la memoria social como marco alternativo de interpretación histórica. Esta contempla las prácticas sociales del parentesco y la objetivación de la continuidad de los grupos de pertenencia en las políticas y lugares de la memoria -corrales de piedra, actividades productivas y pampas de camaruco- en la región de la "meseta" de Chubut. Dichas relaciones con el espacio físico cuestionan tanto las definiciones académicas tradicionales de parentesco y de cacicazgo como las clasificaciones étnicas-nacionales.The "Indigenous issue" as a state policy in Argentina has been accompanied by an academic production of ethnic maps. Hegemonic definitions of these entities used to presume some "essential" elements like the phenotype, the use of language or consanguineous lineage membership. Based on the reformulation of kinship theory, which came from the heuristic model of houses and relatedness theory, we propose an approach to social memory as an alternative framework for historical interpretation. This includes kinship social practices as well as the materialization of group membership's continuity in policies and places of memory -such as stone yards, productive activities, open fields and sacred places- in the Chubut central plateau. Finally, we argue that regarding a physical space, these relations question not only the ethnic-national classifications but also the traditional academic definitions of kinship and chieftaincy.

A Prova por Redução ao Absurdo na Lógica Clássica

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Maria da Paz Nunes de Medeiros

2010-10-01

Full Text Available Embora a logica seja, de urn modo geraJ, concebida como um ramo da filosofia, suas aplic~oes via muito alemdos limites de qualquer disciplina isoladamente considerada (SALMON, 1993. Seu papel principal efomecer meios para determinar a rel~o de consequencia que vige entre as premissas e a conclusao de urn dado argumento. Dentre as tecnicas utilizadas que possibihtarn garantir esta rel~o destaca-se a tecnica por redu¢oao absurdo por ser amplamente aplicada nas cienciasdesde aantiguidade. Suaideiabasics residenofatodequeumaproposi~ nio pode ser verdadeira se dela deduzimos umacontradi~o. Pretende-se, entio, apresentar a estrutura logica de tal teeniea de demonstracao a partir de urn dado sistema formal da logica classica.

Stratigraphy, geochronology, and paleoenvironments of Miocene - Pliocene boundary of San Fernando, Belén (Catamarca, northwest of Argentina)

Science.gov (United States)

Bonini, Ricardo A.; Georgieff, Sergio M.; Candela, Adriana M.

2017-11-01

The Santa María-Hualfín Basin was proposed as a regional synchronous lithostratigraphic depocenter in the geological province of Northwestern Pampean Ranges, Northwestern Argentina. However, new 40Ar-39Ar dating indicates that deposits toward the east, in Santa María Valley (Santa María Department), are younger than the western depocenter in San Fernando (Belén Department). Therefore, it would be more appropriate to study these valleys as separate basins, each one with its own tecto-sedimentary features. The east basin, named in this paper Villavil-Quillay, constitutes an elongated independent basin that developed along the front of the eastern Puna bordering with Papachacra and Durazno Ranges. This basin is composed of more than 3000 m of mudstone, sandstone, conglomerates, volcaniclastic and pyroclastic deposits. Villavil-Quillay basin develops onto a peneplain of Precambrian and lower Cambrian rocks, most of which are metamorphic and granites rocks. The sedimentary fill consists of Cretaceous? and Cenozoic continental deposits. The Cenozoic record is composed of a) the Santa María Group (Miocene-Pliocene), formed by Las Arcas, Chiquimil, Andalhuala and Corral Quemado Formations, and b) the Punaschotter unit (Puna's Gravels in German, Pleistocene). This study involves the Andalhuala, Corral Quemado and Punaschotter deposits cropping out in San Fernando area. The set of identified facies assemblage corresponding to the Andalhuala Formation shows a vertical variation of fluvial sub-environments, varying from permanent sandy braided rivers to gravel rivers and aeolian dunes culminating in an alluvial dry cycle. While facies assemblages of the Corral Quemado Formation allow inferring the development of ephemeral water bodies from secondary channels on the floodplain, the Punaschotter conglomerates indicate the development of gravel channels and bars. Three samples of tuffs interbedded in the sedimentary levels of Andalhuala Formation were dated indicating that

Environmentally friendly wood preservatives formulated with enzymatic-hydrolyzed okara, copper and/or boron salts

International Nuclear Information System (INIS)

Ahn, Sye Hee; Oh, Sei Chang; Choi, In-gyu; Han, Gyu-seong; Jeong, Han-seob; Kim, Ki-woo; Yoon, Young-ho; Yang, In

2010-01-01

Novel biocides, such as copper azole (CuAz) and ammoniacal copper quaternary (ACQ), are extensively used as substitutes for chromate copper arsenate (CCA) in wood preservation. However, the expense of these biocides has necessitated the development of cost-effective and environmentally friendly wood preservatives. This study was conducted to investigate the effectiveness against decaying fungi of the preservatives formulated with enzymatic-hydrolyzed okara (OK), which is an organic waste produced from the manufacture of tofu, CuCl 2 (CC) and/or Na 2 B 4 O 7 .10H 2 O (B). With the addition of NH 4 OH as a dissociating agent, the addition of OK facilitated the target retention of most of the OK/CC and OK/CC/B preservative formulations in wood blocks. The OK-based wood preservatives (OK-WPs) were stable against hot-water leaching. When compared with control and CC-treated wood blocks, the leached wood blocks treated with OK/CC and OK/CC/B formulations showed excellent decay resistance against both Postia placenta and Gloeophyllum trabeum, especially when OK was hydrolyzed by Celluclast at a loading level of 0.1 ml/g. Scanning electron microscopy (SEM) and SEM-energy dispersive X-ray (SEM-EDX) spectrometry analyses demonstrated that preservative complexes, such as OK-CC and OK-CC-B, existed in the wood blocks treated with OK/CC and OK/CC/B formulations. This study results support the potential application of OK-WPs as environmentally friendly wood preservatives capable of replacing CuAz and ACQ.

Environmentally friendly wood preservatives formulated with enzymatic-hydrolyzed okara, copper and/or boron salts

Energy Technology Data Exchange (ETDEWEB)

Ahn, Sye Hee; Oh, Sei Chang [Department of Forest Resources, Daegu University, Gyeongsan 712-714 (Korea, Republic of); Choi, In-gyu [Department of Forest Sciences, Seoul National University, Seoul 151-921 (Korea, Republic of); Han, Gyu-seong [Department of Wood and Paper Sciences, Chungbuk National University, Cheongju 361-763 (Korea, Republic of); Jeong, Han-seob [Department of Forest Sciences, Seoul National University, Seoul 151-921 (Korea, Republic of); Kim, Ki-woo [National Instrumentation Center for Environmental Management, Seoul National University, Seoul 151-921 (Korea, Republic of); Yoon, Young-ho [KCI Co. Ltd., Seosan, Chungcheongnam-do 356-874 (Korea, Republic of); Yang, In, E-mail: dahadad2000@yahoo.com [Research Institute for Agriculture and Life Sciences, Seoul National University, San 56-1 Sillim-Dong, Kwanak-gu, Seoul 151-921 (Korea, Republic of)

2010-06-15

Novel biocides, such as copper azole (CuAz) and ammoniacal copper quaternary (ACQ), are extensively used as substitutes for chromate copper arsenate (CCA) in wood preservation. However, the expense of these biocides has necessitated the development of cost-effective and environmentally friendly wood preservatives. This study was conducted to investigate the effectiveness against decaying fungi of the preservatives formulated with enzymatic-hydrolyzed okara (OK), which is an organic waste produced from the manufacture of tofu, CuCl{sub 2} (CC) and/or Na{sub 2}B{sub 4}O{sub 7}.10H{sub 2}O (B). With the addition of NH{sub 4}OH as a dissociating agent, the addition of OK facilitated the target retention of most of the OK/CC and OK/CC/B preservative formulations in wood blocks. The OK-based wood preservatives (OK-WPs) were stable against hot-water leaching. When compared with control and CC-treated wood blocks, the leached wood blocks treated with OK/CC and OK/CC/B formulations showed excellent decay resistance against both Postia placenta and Gloeophyllum trabeum, especially when OK was hydrolyzed by Celluclast at a loading level of 0.1 ml/g. Scanning electron microscopy (SEM) and SEM-energy dispersive X-ray (SEM-EDX) spectrometry analyses demonstrated that preservative complexes, such as OK-CC and OK-CC-B, existed in the wood blocks treated with OK/CC and OK/CC/B formulations. This study results support the potential application of OK-WPs as environmentally friendly wood preservatives capable of replacing CuAz and ACQ.

Change in Weather Research and Forecasting (WRF) Model Accuracy with Age of Input Data from the Global Forecast System (GFS)

Science.gov (United States)

2016-09-01

were downloaded from the University of Wyoming’s weather website (http://www.weather.uwyo.edu/upperair/sounding.html). An alternative site is the RAOB...Midwest US Amarillo, TX AMA 2016-01-02-12 37.12, –98.66 Dodge City, KS DDC and Lamont, OK LMN 2016-02-10-12 Norman, OK OUN...0-, 24-, 48-, 72-, or 96-h forecast from the same day, 1, 2, 3, or 4 days earlier, respectively. For example, for a 12 Coordinated Universal Time

Organizing for a Peaceful Crowd: An Example of a Football Match

Directory of Open Access Journals (Sweden)

Ingrid Hylander

2010-03-01

Full Text Available Crowd violence has interested researchers in social psychology for many years and is an important issue for sports psychology (STOTT, ADANG, LIVINGSTONE & SCHREIBER, 2007; STOTT, HUTCHINSON & DRURY, 2001; RUSSELL, 2004; MUSTONEN, ARMS & RUSSELL, 1996. Riots in crowds have been explained from different theoretical perspectives (HYLANDER, 2008, such as individual differences, de-individuation (PRENTICE-DUNN & ROGERS, 1989, group interaction (DRURY & REICHER, 2000, history (GUTTMAN, 1986, 1998 and cultural perspectives (CRABBE, 2003. In this study, a social psychology model focusing on group interaction, the Aggravation and Mitigation (AM model (GUVÅ & HYLANDER, 2008; GRANSTRÖM, 2008; GRANSTRÖM & ROSANDER, 2008, is used as a means of analysis. This article applies the AM model to a sporting event to identify if and how peacemaking processes can be detected. Furthermore, the intention is to discern and illuminate organizational strategies that maybe linked to peacemaking processes. The main results indicate that when arrangements are based on (a "festival-making," (b arrangements for basic needs and recognizable order and (c the creation of a superordinate identity, then the outcome of mass events may turn out peaceful, which is also in line with the AM model. URN: urn:nbn:de:0114-fqs100283

Speaker segmentation and clustering

OpenAIRE

Kotti, M; Moschou, V; Kotropoulos, C

2008-01-01

07.08.13 KB. Ok to add the accepted version to Spiral, Elsevier says ok whlile mandate not enforced. This survey focuses on two challenging speech processing topics, namely: speaker segmentation and speaker clustering. Speaker segmentation aims at finding speaker change points in an audio stream, whereas speaker clustering aims at grouping speech segments based on speaker characteristics. Model-based, metric-based, and hybrid speaker segmentation algorithms are reviewed. Concerning speaker...

Probabilistic Inference: Task Dependency and Individual Differences of Probability Weighting Revealed by Hierarchical Bayesian Modeling.

Science.gov (United States)

Boos, Moritz; Seer, Caroline; Lange, Florian; Kopp, Bruno

2016-01-01

Cognitive determinants of probabilistic inference were examined using hierarchical Bayesian modeling techniques. A classic urn-ball paradigm served as experimental strategy, involving a factorial two (prior probabilities) by two (likelihoods) design. Five computational models of cognitive processes were compared with the observed behavior. Parameter-free Bayesian posterior probabilities and parameter-free base rate neglect provided inadequate models of probabilistic inference. The introduction of distorted subjective probabilities yielded more robust and generalizable results. A general class of (inverted) S-shaped probability weighting functions had been proposed; however, the possibility of large differences in probability distortions not only across experimental conditions, but also across individuals, seems critical for the model's success. It also seems advantageous to consider individual differences in parameters of probability weighting as being sampled from weakly informative prior distributions of individual parameter values. Thus, the results from hierarchical Bayesian modeling converge with previous results in revealing that probability weighting parameters show considerable task dependency and individual differences. Methodologically, this work exemplifies the usefulness of hierarchical Bayesian modeling techniques for cognitive psychology. Theoretically, human probabilistic inference might be best described as the application of individualized strategic policies for Bayesian belief revision.

Opening up to Big Data: Computer-Assisted Analysis of Textual Data in Social Sciences

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Gregor Wiedemann

2013-05-01

Full Text Available Two developments in computational text analysis may change the way qualitative data analysis in social sciences is performed: 1. the availability of digital text worth to investigate is growing rapidly, and 2. the improvement of algorithmic information extraction approaches, also called text mining, allows for further bridging the gap between qualitative and quantitative text analysis. The key factor hereby is the inclusion of context into computational linguistic models which extends conventional computational content analysis towards the extraction of meaning. To clarify methodological differences of various computer-assisted text analysis approaches the article suggests a typology from the perspective of a qualitative researcher. This typology shows compatibilities between manual qualitative data analysis methods and computational, rather quantitative approaches for large scale mixed method text analysis designs. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1302231

Narrative Structure in Religious Conversion: The Case of Converts to the Pentecostal Methodist Church of Chile

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Víctor Hugo Masías

2010-01-01

Full Text Available In this article I analyze the narrative structure of the discourse of individuals who have converted to the Pentecostal Methodist Church of Chile. I use Grounded Theory to analyze 11 conversion narratives, which were collected through a narrative-biographical interview, and with support from the graphical tool called Story-Line. The results identify two types of conversion narrative structure. The first one is understood as a personal salvation narrative, the second one is described as a spiritual renewal narrative. This allowed the construction of a conceptual model illustrating the way in which the conversion narrative of the convert is structured. The discussion is centered on comparing the findings of this study with other similar investigations; debating the similarities and differences found in conversion narratives and their differing philosophies. URN: urn:nbn:de:0114-fqs1001210

Cooperation Relationships in Community Prevention Committees—Neglected by Qualitative Social Research?

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Henning van den Brink

2005-09-01

Full Text Available There are very few qualitative studies about the different models of cooperation founded in the last years in the field of community crime prevention in Germany. Qualitative methods are helpful in identifying and in analyzing the conflicts in interest and the negotiation process that takes place among the local institutes. The conflict in interest makes it difficult to work together and in the worst case it can completely block cooperation. With the help of qualitative methods, the soft skills and structural requirements for successful cooperation can be identified and discussed. The aim of this article is to show that it is necessary to examine the "inner life" of cooperation especially in crime prevention committees by using qualitative methods and with more rigor than in the past. URN: urn:nbn:de:0114-fqs0503202

Improvement of Hydrological Simulations by Applying Daily Precipitation Interpolation Schemes in Meso-Scale Catchments

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Mateusz Szcześniak

2015-02-01

Full Text Available Ground-based precipitation data are still the dominant input type for hydrological models. Spatial variability in precipitation can be represented by spatially interpolating gauge data using various techniques. In this study, the effect of daily precipitation interpolation methods on discharge simulations using the semi-distributed SWAT (Soil and Water Assessment Tool model over a 30-year period is examined. The study was carried out in 11 meso-scale (119–3935 km2 sub-catchments lying in the Sulejów reservoir catchment in central Poland. Four methods were tested: the default SWAT method (Def based on the Nearest Neighbour technique, Thiessen Polygons (TP, Inverse Distance Weighted (IDW and Ordinary Kriging (OK. =The evaluation of methods was performed using a semi-automated calibration program SUFI-2 (Sequential Uncertainty Fitting Procedure Version 2 with two objective functions: Nash-Sutcliffe Efficiency (NSE and the adjusted R2 coefficient (bR2. The results show that: (1 the most complex OK method outperformed other methods in terms of NSE; and (2 OK, IDW, and TP outperformed Def in terms of bR2. The median difference in daily/monthly NSE between OK and Def/TP/IDW calculated across all catchments ranged between 0.05 and 0.15, while the median difference between TP/IDW/OK and Def ranged between 0.05 and 0.07. The differences between pairs of interpolation methods were, however, spatially variable and a part of this variability was attributed to catchment properties: catchments characterised by low station density and low coefficient of variation of daily flows experienced more pronounced improvement resulting from using interpolation methods. Methods providing higher precipitation estimates often resulted in a better model performance. The implication from this study is that appropriate consideration of spatial precipitation variability (often neglected by model users that can be achieved using relatively simple interpolation methods can

Perdida de carga en conductos de hierro galvanizado conduciendo agua residual de instalaciones de gallinas ponedoras

OpenAIRE

RODRIGUES DE SOUZA, José ANTONIO; ASTONI MOREIRA, DÉBORA; OLIVEIRA BATISTA, RAFAEL; OSORIO S., JAIRO ALEXANDER; ZAPATA MARÍN, OLGA LUCÍA

2011-01-01

Las operaciones relacionadas con la producción de aves de corral pueden generar efluentes procedentes de fuentes distintas, incluida la escorrentía originada en las jaulas, alimentación y abastecimiento de agua de las aves y de las instalaciones de almacenamiento y manejo de residuos. En todo proyecto de explotación de aves de corral, se debe tener en cuenta el manejo de residuos y aguas residuales, las cuales pueden ser conducidas en tuberías de hierro galvanizado. El objetivo de este trabaj...

An assessment of air pollutant exposure methods in Mexico City, Mexico.

Science.gov (United States)

Rivera-González, Luis O; Zhang, Zhenzhen; Sánchez, Brisa N; Zhang, Kai; Brown, Daniel G; Rojas-Bracho, Leonora; Osornio-Vargas, Alvaro; Vadillo-Ortega, Felipe; O'Neill, Marie S

2015-05-01

Geostatistical interpolation methods to estimate individual exposure to outdoor air pollutants can be used in pregnancy cohorts where personal exposure data are not collected. Our objectives were to a) develop four assessment methods (citywide average (CWA); nearest monitor (NM); inverse distance weighting (IDW); and ordinary Kriging (OK)), and b) compare daily metrics and cross-validations of interpolation models. We obtained 2008 hourly data from Mexico City's outdoor air monitoring network for PM10, PM2.5, O3, CO, NO2, and SO2 and constructed daily exposure metrics for 1,000 simulated individual locations across five populated geographic zones. Descriptive statistics from all methods were calculated for dry and wet seasons, and by zone. We also evaluated IDW and OK methods' ability to predict measured concentrations at monitors using cross validation and a coefficient of variation (COV). All methods were performed using SAS 9.3, except ordinary Kriging which was modeled using R's gstat package. Overall, mean concentrations and standard deviations were similar among the different methods for each pollutant. Correlations between methods were generally high (r=0.77 to 0.99). However, ranges of estimated concentrations determined by NM, IDW, and OK were wider than the ranges for CWA. Root mean square errors for OK were consistently equal to or lower than for the IDW method. OK standard errors varied considerably between pollutants and the computed COVs ranged from 0.46 (least error) for SO2 and PM10 to 3.91 (most error) for PM2.5. OK predicted concentrations measured at the monitors better than IDW and NM. Given the similarity in results for the exposure methods, OK is preferred because this method alone provides predicted standard errors which can be incorporated in statistical models. The daily estimated exposures calculated using these different exposure methods provide flexibility to evaluate multiple windows of exposure during pregnancy, not just trimester or

Probabilistic inference: Task dependency and individual differences of probability weighting revealed by hierarchical Bayesian modelling

Directory of Open Access Journals (Sweden)

Moritz eBoos

2016-05-01

Full Text Available Cognitive determinants of probabilistic inference were examined using hierarchical Bayesian modelling techniques. A classic urn-ball paradigm served as experimental strategy, involving a factorial two (prior probabilities by two (likelihoods design. Five computational models of cognitive processes were compared with the observed behaviour. Parameter-free Bayesian posterior probabilities and parameter-free base rate neglect provided inadequate models of probabilistic inference. The introduction of distorted subjective probabilities yielded more robust and generalizable results. A general class of (inverted S-shaped probability weighting functions had been proposed; however, the possibility of large differences in probability distortions not only across experimental conditions, but also across individuals, seems critical for the model’s success. It also seems advantageous to consider individual differences in parameters of probability weighting as being sampled from weakly informative prior distributions of individual parameter values. Thus, the results from hierarchical Bayesian modelling converge with previous results in revealing that probability weighting parameters show considerable task dependency and individual differences. Methodologically, this work exemplifies the usefulness of hierarchical Bayesian modelling techniques for cognitive psychology. Theoretically, human probabilistic inference might be best described as the application of individualized strategic policies for Bayesian belief revision.

DİŞ HEKİMLİĞİNDE ORAL CERRAHİ İŞLEMLER SONRASINDA EN ÇOK TERCİH EDİLEN ANALJEZİK İLAÇLAR (NSAİ) VE ETKİNLİKLERİ

OpenAIRE

KÖSE, İbrahim; KOPARAL, Mahmut; ALAN, Hilal; KIRTAY, Mustafa; ÇİÇEK, Yasin

2015-01-01

Diş hekimliğinde özellikle oral cerrahi müdahaleler neticesinde  ağrı, şişlik ve trismus gibi rahatsızlıklar meydana gelebilmektedir. Kuşkusuz, meydana gelen problemler ve inflamatuvar süreci farmakolojik olarak kontrol altına almak amacıyla birçok analjezik ilaç kullanılmaktadır. Bu çalışmanın amacı; oral cerrahi müdahaleler sonrası kullanılan ağrı kesici ilaçların, kullanımı ve etkinliği konusundaki mevcut bilgileri güncellemek ve daha önce yapılmış çalışmaların ışığı altında uygulama yönte...

A Fast Implicit Finite Difference Method for Fractional Advection-Dispersion Equations with Fractional Derivative Boundary Conditions

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Taohua Liu

2017-01-01

Full Text Available Fractional advection-dispersion equations, as generalizations of classical integer-order advection-dispersion equations, are used to model the transport of passive tracers carried by fluid flow in a porous medium. In this paper, we develop an implicit finite difference method for fractional advection-dispersion equations with fractional derivative boundary conditions. First-order consistency, solvability, unconditional stability, and first-order convergence of the method are proven. Then, we present a fast iterative method for the implicit finite difference scheme, which only requires storage of O(K and computational cost of O(Klog⁡K. Traditionally, the Gaussian elimination method requires storage of O(K2 and computational cost of O(K3. Finally, the accuracy and efficiency of the method are checked with a numerical example.

Review: Thomas Brüsemeister (2000). Qualitative Forschung. Ein Überblick [Qualitative Research: An Overview

OpenAIRE

Martin Spetsmann-Kunkel

2002-01-01

Thomas BRÜSEMEISTER's book Qualitative Forschung. Ein Überblick [Qualitative Research: An Overview] presents five different methods of social research: case study, narrative interview, grounded theory, ethnomethododical conversation analysis, and objective hermeneutics. These methods are so described as to make them clear and understandable for university entrants and lay people in the area of qualitative social research. URN: urn:nbn:de:0114-fqs020252

Loriot as a Symbolic Interactionist. Or: Why We Sometimes Need to Negotiate Social Order Even in a Bathtub

OpenAIRE

Dirk Koob

2007-01-01

The following essay intends to outline both the theoretical (action theory) and methodological essentials of Symbolic Interactionism in a predominantly student-oriented way. The importance of norms in generating social order is discussed by referring to a satirical example. Almost unnoticed the reader is made familiar with the central terminology as well as with the reconstructive methodology of Symbolic Interactionism. URN: urn:nbn:de:0114-fqs0701279

Venezuela’s Corruption On the Rise: Fourteen Years of Chavismo

Science.gov (United States)

2016-09-01

Venezuela’s abundance of oil has led to a history of failed economic models used to attempt to temper the Resource Curse. Javier Corrales from Harvard ...the 1990s and beyond,” ReVista Harvard Review of Latin America, no. Fall (1999), accessed March 11, 2016, http://revista.drclas.harvard.edu/ book ...incorporate a three-prong anti-corruption approach, including political, economic , and social accountability reforms with market-friendly social democratic

Inferring category characteristics from sample characteristics: inductive reasoning and social projection.

Science.gov (United States)

Krueger, J; Clement, R W

1996-03-01

Inductive reasoning involves generalization from sample observations to categories. This research examined the conditions under which generalizations go beyond the boundaries of the sampled categories. In Experiment 1, participants sampled colored chips from urns. When categorization was not salient, participants revised their estimates of the probability of a particular color even in urns they had not sampled. As categorization became more salient, generalization became limited to the sampled urn. In Experiment 2 the salience of categorization in social induction was varied. When social categorization was not salient, participants projected their own responses to test items to members of a laboratory group even when they themselves did not belong to this group. When salience increased, projection decreased among nonmembers but not among members. In Experiment 3 these results were replicated in a field setting.

Caracterización petrográfica y geoquímica del batolito Cerro Aspero-Alpa Corral (32°34'-32°42' LS y 64°43'-64°52' LO, provincia de Córdoba, Argentina

Directory of Open Access Journals (Sweden)

Porta, G.

1992-12-01

Full Text Available The Cerro Aspero-Alpa Corral (CA-AC batholith is a 440 km2 granite body present in the Southern edge of the Eastern Pampean Ranges, Córdoba province, central Argentina. The intrusive body of probably paleozoic age shows both post-tectonic and epizonal character. Country rocks include Upper Precambrian-Lower Paleozoic metasedimentary rocks mainly represented by mica-schists, gneisses and migmatites, locally interrupted by minor amphibolite and marble outcrops.This paper deals with representative petrographic and geochemical data that characterize a 150 km2 central stripe between 32°34'-32°42'S and 64°43'-64°52'W.Three granitic facies have been distinguished based on their distinctive modal mineralogy and texture, and upon well known chemical parameters.A K-feldspar megacryst porphydic-type is the areally prevalent facies, but dykes of micro- leucogranites and biotite-phenocryst bearing granite are also well represented. They are all monzogranites of subalkaline and peraluminous chemistry. Their mineralogy shows variable proportions of QAP constituents and micas, with minor phases represented by Fe-Ti oxides, apatite (Ap, titanite (Tt, allanite (Aln.Microgranular enclaves, abundantly distributed in the porphydic facies, provide valuable information for a better understanding of parental magma evolution.The high-Ca content of the melt makes this body quite distinctive compared to its larger northern neighbour, the Achala batholith.Pegmatite and aplite bodies, as well as fluorite bearing breccias and quartz veins, barren or mineralized, are also present within the CA-AC batholith.El batolito Cerro Aspero-Alpa Corral (CA-AC es un cuerpo granítico que aflora en el extremo sur de las Sierras Pampeanas Orientales, en la provincia de Córdoba, República Argentina, cubriendo una superficie cercana a los 440 km2.Es un cuerpo intrusivo postcinemático de probable edad paleozoica. Las rocas encajantes son metamorfitas correspondientes al Prec

HÜCRESEL OTOMATA VE BİLGİSAYAR GRAFİKLERİ

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Şen ÇAKIR

1999-01-01

Full Text Available Hücresel Otomata (CA çeşitli fiziksel işlemler için model temin eden basit matematik sistemleridir. Önemsiz veya küçük değişikliklerin ve basit kuralların sistemlerin davranışlarında nasıl çok büyük değişikliklere yolaçtığını gösterirler. İlginç şekillerin zengin bir kaynağı olarak bilgisayar grafikleri aracı olarak da kullanılmaktadırlar. Son yıllarda CA birçok bilim adamının dikkatini çekmiştir. Günümüzde CA ekolojiden görüntü işlemeye kadar birçok alanda kullanılır. Bu makalede oldukça basit CA kuralları ile çok sayıda karmaşık ve harika modelin yaratılabileceği gösterilmektedir

Loriot as a Symbolic Interactionist. Or: Why We Sometimes Need to Negotiate Social Order Even in a Bathtub

Directory of Open Access Journals (Sweden)

Dirk Koob

2007-01-01

Full Text Available The following essay intends to outline both the theoretical (action theory and methodological essentials of Symbolic Interactionism in a predominantly student-oriented way. The importance of norms in generating social order is discussed by referring to a satirical example. Almost unnoticed the reader is made familiar with the central terminology as well as with the reconstructive methodology of Symbolic Interactionism. URN: urn:nbn:de:0114-fqs0701279

Conference Report: The First ATLAS.ti User Conference

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Jeanine C. Evers

2014-01-01

Full Text Available This report on the First ATLAS.ti User Conference shares our impressions and experiences as longstanding ATLAS.ti users and trainers about the First ATLAS.ti User Conference in Berlin 2013. The origins, conceptual principles and development of the program are outlined, the conference themes discussed and experiences shared. Finally, the future of the program is discussed. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1401197

Polnische qualitative Soziologie: Entwicklung und Hauptthemen

OpenAIRE

Konecki, Krzysztof T.; Kacperczyk, Anna M.; Marciniak, Lukasz T.

2005-01-01

In dem vorliegenden Beitrag wird die Entwicklung der qualitativen Soziologie in Polen rekonstruiert, indem deren wesentliche intellektuelle Wurzeln und einige Hauptthemen der polnischen Soziologie vorgestellt werden. Romantizismus und die induktive Methode sind essenzielle Elemente für die Entwicklung der Disziplin in Polen gewesen und Charakteristika ihrer Besonderheit. Die Bedeutung von Florian ZNANIECKI für die Entstehung der polnischen qualitativen Soziologie wird gewürdigt. URN: urn:n...

Groundwater Governance and the Growth of Center Pivot Irrigation in Cimarron County, OK and Union County, NM: Implications for Community Vulnerability to Drought

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Kathryn Wenger

2017-01-01

Full Text Available Cimarron County, Oklahoma and Union County, New Mexico, neighboring counties in the Southern High Plains, are part of a vital agricultural region in the United States. This region experiences extended periods of cyclical drought threatening its ability to produce, creating an incentive for extensive center pivot irrigation (CPI. Center pivots draw from the rapidly depleting High Plains Aquifer System. As a result, the prospect of long-term sustainability for these agricultural communities is questionable. We use Remote Sensing and Geographic Information Systems to quantify growth in land irrigated by CPI between the 1950s and 2014, and key informant interviews to explore local perspectives on the causes and impact of such growth. In Cimarron County, OK, CPI increased by the mid-1980s, and has continually increased since. Results suggest adaptation to drought, a depleting aquifer, high corn prices, and less rigid groundwater regulations contribute to CPI growth. Conversely, CPI in Union County, NM, increased until 2010, and then declined. Results also suggest that drought-related agricultural changes and more aggressive well drilling regulations contribute to this decrease. Nevertheless, in both counties, there is a growing concern over the depleting aquifer, the long-term sustainability of CPI, and the region’s economic future.

Clinical effect of concomitant use of non-specific immunopotentiator on 172 cases of primary lung cancer (stage 3, 4) treated with radiation combined with chemotherapy

International Nuclear Information System (INIS)

Hiyoshi, Yukio; Ogawa, Yasuhiro; Imajo, Yoshinari

1981-01-01

Between 1975 and 1979, 209 cases of primary lung cancer admitted the department of radiology were treated with radiation combined with chemotherapy. The clinical effect of concomitant use of non-specific immunopotentiator OK-432 and PSK was studied about stage 3, and stage 4. Survival curves were evaluated between the patients with OK-432 and/or PSK and those without immunotherapy. In 91 cases in stage 3, fifty percent survival period was found to be 12.2 months for 27 cases with OK-432, 14.4 months for 12 cases with combined use of OK-432 and PSK, 9.0 months for 24 cases with PSK, and 7.5 months for 28 cases without immunotherapy, respectively. Noticeable prolongation of fifty percent survival period was observed in the cases with combined use of OK-432 and PSK, OK-432, and PSK, inorder, as compared with those without immunotherapy. One-year survival rate was 51.9% for cases with OK-432, 66.7% with combined use OK-432 and PSK, 34.8% with PSK, and 25.0% without immunotherapy, respectively. In 81 cases in stage 4, fifty percent survival period was found to be 7.0 months for 24 cases with OK-432, 5.0 months for 8 cases with combined use of OK-432 and PSK, 7.6 months for 13 cases with PSK, and 3.3 months for 36 cases without immunotherapy, respectively. One-year survival rate was 16.7% for cases with OK-432, 25.0% with combined use of OK-432 and PSK, 15.4% with PSK and 5.6% without immunotherapy, respectively. (J.P.N.)

Control del Chagas en comunidades guaraníes: conocimiento y hábitos higiénicos dentro del Proyecto de Mejoramiento de Viviendas en Bolivia Control of Chagas' disease in Guarani Communities: project to improve living conditions in Bolivia

Directory of Open Access Journals (Sweden)

J. Verdú

2003-04-01

Full Text Available El objetivo fue identificar el conocimiento y control del vector (Triatoma infestans transmisor de la enfermedad de Chagas en comunidades guaraníes de Bolivia, conocido como vinchuca. Se trata de un estudio descriptivo de una serie de 98 casos mediante cuestionario semiestructurado sobre: conocimiento de la vinchuca, si produce alguna enfermedad, nombre de la enfermedad y sus consecuencias, así como las conductas de higiene: patio, vivienda, corrales. La vinchuca fue suficientemente conocida (98%, aunque sólo el 14,3% identificó el nombre de la enfermedad. Pese a ser ambientes apropiados para la proliferación de vinchucas, se limpian con poca frecuencia: el 28,6% limpia la vivienda, el 42,9% el patio y el 7,1% el corral. Se evidencia una división sexual del trabajo: mientras las mujeres limpian la vivienda y el patio, los varones limpian los corrales. La experiencia enseña el valor del proyecto de construcción de viviendas saludables y educación para la salud en la medida en que la comunidad los valora. Probablemente, las mujeres son el mejor grupo destinatario, pues realizan más tareas preventivas y no se ausentan con tanta frecuencia de la comunidad.The aim of this study was to identify knowledge and control of vectorial transmission (Triatoma infestans, known as vinchuca of Chagas' disease in Guaraní Communities in Bolivia. We performed a descriptive study of a series of 98 individuals through a semi-structured questionnaire. Interviewees were asked about their familiarity with vinchuca, whether they thought vinchuca produced disease, the name of the disease and its consequences, as well as behavior related to eliminating the domestic insect vectors, such as cleaning of the home, backyard and corral. The insect vector was sufficiently well known (98%, although the name of the disease was identified by only 14.3% of the interviewees. Although the dwellings favored insect proliferation, they were not frequently cleaned: 28.6% cleaned

The use of graph theory in the sensitivity analysis of the model output: a second order screening method

International Nuclear Information System (INIS)

Campolongo, Francesca; Braddock, Roger

1999-01-01

Sensitivity analysis screening methods aim to isolate the most important factors in experiments involving a large number of significant factors and interactions. This paper extends the one-factor-at-a-time screening method proposed by Morris. The new method, in addition to the 'overall' sensitivity measures already provided by the traditional Morris method, offers estimates of the two-factor interaction effects. The number of model evaluations required is O(k 2 ), where k is the number of model input factors. The efficient sampling strategy in the parameter space is based on concepts of graph theory and on the solution of the 'handcuffed prisoner problem'

LTV1 raidījuma „Aizliegtais paņēmiens” ētiskie aspekti

OpenAIRE

Zeikate, Ieva

2015-01-01

Bakalaura darba tēma ir LTV1 Raidījuma „Aizliegtais paľēmiens” ētiskie aspekti. Darba mērķis ir izpētīt raidījuma saturu, noskaidrot, vai tajā tiek ievēroti ţurnālistikas ētikas principi un vērtības, noteikt raidījuma mērķus un izmantotos līdzekļus, kā arī to saskaľotību, veicot raidījuma izpēti aptuveni gada garumā. Teorija balstīta par televīziju, pētnieciskās ţurnālistikas teorētisko raksturojumu, ētiku un ţurnālistikas ētikas pamatprincipiem. Izvēlētās pētniecības metodes i...

The Psycho-Affective Echoes of Colonialism in Fieldwork Relations

Directory of Open Access Journals (Sweden)

Robert Garot

2013-11-01

Full Text Available This article describes the varieties of relations with African immigrant interviewees in Tuscany as experienced by a white male interviewer from the United States. Franz FANON's discussion of the psycho-affective consequences of colonialism is vital for understanding how naïve and romantic notions of fieldwork relations are disingenuous, counter-productive and perhaps destructive in a neo-colonial landscape. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1401125

Conference Report: "Ethnological vs. Sociological Ethnography—Considering Scope and Potential for Distinction"

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Thomas Scheffer

2010-11-01

Full Text Available The respective disciplinary appropriations of the ethnographic approach in ethnology and sociology formed the core of the workshop. The following report lays out the contrasts and similarities debated. On this basis, it explores deeper systematic differences using the conceptual triad of field, site, and research object. The report concludes with core themes for debate in a follow-up workshop in 2011. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1101256

Duke storage rink UV/VUV FEL: Status and prospects

Energy Technology Data Exchange (ETDEWEB)

Litvinenko, V.N.; Burnham, B.; Madey, J.M.J. [Duke Univ., Durham, NC (United States)] [and others

1995-12-31

The 1 GeV Duke storage ring was successfully commissioned with parameters exceeding initial specification. The OK-4 FEL has arrived at the Duke FEL laboratory from the Novosibirsk Institute of Nuclear Physics. The OK-4 installation and commissioning is in progress. In this paper we describe the up-to-date status of the Duke storage ring and the OK-4 FEL. The projected performance of the OK-4 UV/VUV FEL is presented based on the electron beam parameters achieved. Initial plans to operate the OK-4 UV/VUV FEL at the Duke 1 GeV storage ring are outlined. Future plans and prospects of both the OK-4 FEL and the Duke storage ring are discussed.

Stochastic aspects of Lanchester's theory of warfare

OpenAIRE

Kingman, J. F. C.

2002-01-01

A Markov chain model for a battle between two opposing forces is formulated, which is a stochastic version of one studied by F. W. Lanchester. Solutions of the backward equations for the final state yield martingales and stopping identities, but a more powerful technique is a time-reversal analogue of a known method for studying urn models. A general version of a remarkable result of Williams and McIlroy (1998) is proved.

Review: Johanna Mutzl (2005. "Die Macht von Dreien ..." Medienhexen und moderne Fangemeinschaften. Bedeutungskonstruktionen im Internet ["Three's Power"—Media Witches and Modern Fan Communities. The Construction of Meaning on the Internet

Directory of Open Access Journals (Sweden)

Angela Tillmann

2006-03-01

Full Text Available Johanna MUTZL's study is concerned with the construction of meaning on the Internet amongst fans of the TV series Charmed. Conducted in both German and English, the study is based on a discourse and genre analysis, an e-mail questionnaire, and a grounded theory evaluation of over 200 fan sites. The study persuasively demonstrates how the Internet has contributed to the development of new means of production and distribution as well as the formation of creative communities. According to this study, fans derive personal relevance for their own, daily experience from media images of womanhood and witchcraft. Constructing personally relevant discourses, their productivity is setting up new (discursive spaces on fan pages and social communication networks on the Internet. MUTZL describes these as "fan spaces", in reference to Doreen MASSEY (1994, whose approach she has elaborated into her own three-pronged model. URN: urn:nbn:de:0114-fqs0602287

Analysis of a normalized QR filter using Bayesian description of propagated data

Czech Academy of Sciences Publication Activity Database

Kadlec, Jiří; Schier, Jan

1999-01-01

Roč. 13, č. 6 (1999), s. 487-505 ISSN 0890-6327 Grant - others:Commission EC(XE) ESPRIT 23544 HSLA; Commission EC(XE) ESPRIT 25729 ProDaCTool; MŠMT(CZ) OK 314; MŠMT(CZ) OK 317 Program:OK; OK Institutional research plan: AV0Z1075907 Subject RIV: JC - Computer Hardware ; Software Impact factor: 0.291, year: 1999

Combined effects of radiotherapy and non-specific immunotherapy

International Nuclear Information System (INIS)

Yamashita, Takashi; Hayakawa, Yukiko; Mochizuki, Yukio

1985-01-01

Local and systemic effects of the combined use of radiotherapy and administration of OK-432 were examined using tumor-bearing mice. Tumor regrowth was inhibited by local administration of OK-432 following radiotherapy. Systemic inhibitory effects of OK-432 on tumors were not seen. When radiotherapy is performed in combination with administration of OK-432, synergistic effects will be observed. (Namekawa, K.)

Review: Norman K. Denzin & Yvonna S. Lincoln (Hrsg.) (2002). The Qualitative Inquiry Reader

OpenAIRE

Gergen, Mary

2002-01-01

Dieser Reader, der eine Auswahl von 20 Beiträgen aus der Zeitschrift Qualitative Inquiry der letzten sieben Jahre vereint, betont die Darstellung neuer Formen qualitativer Forschung. Dies beinhaltet u.a. Ethnographien und Lyrik und ist verbunden mit dem Ziel, sowohl neue Methoden und einen kritischen Rahmen für die Interpretation dieser Art von Arbeiten vorzustellen, als auch eine reflexive Sensibilität für die kritischen und ethischen Dimensionen von Forschung zu entwickeln. URN: urn:nbn:...

Review: Gisela Brünner & Elisabeth Gülich (Eds. (2002. Krankheit verstehen. Interdisziplinäre Beiträge zur Sprache in Krankheitsdarstellungen [Understanding Illness. Interdisciplinary Approaches to Communication about Illness

Directory of Open Access Journals (Sweden)

Rudolf Schmitt

2002-09-01

Full Text Available GÜLICH and BRÜNNER's book presents different approaches to linguistics, social science, psychosomatics, literary history and therapeutic approaches in the discourse about somatic and mental illness. Some articles are very inspiring; some seem to have a narrow point of view. Many of them converge on the topic of metaphor and the cognitive metaphor theory of LAKOFF and JOHNSON, that enrich the methodical and theoretical repertoire of qualitative research. URN: urn:nbn:de:0114-fqs020382

Contribution of the Epistemology of the Known Subject to the Qualitative Study of Poverty Situations, Identity, and Social Representations

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Irene Vasilachis de Gialdino

2007-09-01

Full Text Available In this paper I intend to describe the path of empirically grounded epistemological reflection that has led me from the epistemology of the knowing subject to the epistemology of the known subject, characterizing identity from the latter perspective. Also, based on the assumptions of the epistemology of the known subject, I develop a qualitative methodology to account for poverty situations and for identity construction processes in the written press. URN: urn:nbn:de:0114-fqs070364

The Analysis of Discourses Which Form a Part of the Regime of Practices of Governing: A Governmentality Studies Approach

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Victoria Haidar

2007-05-01

Full Text Available From the perspective of governmentality studies and a critical discourse analysis this paper looks at the interfaces between a social point of view and the mobilization of techniques of decision making. This is illustrated by the discourse analysis of the program between 1907 and 1915 of the National Department of Work in Argentina through which the governing of risks at work was organized within a liberal rational framework. URN: urn:nbn:de:0114-fqs070287

Repositioning Warts & All: A Response to Coteaching Researchers

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Jennifer Gallo-Fox

2006-09-01

Full Text Available This paper is a response to our colleague's perspectives on our paper (GALLOFOX, WASSELL, SCANTLEBURY, & JUCK, 2006, that addressed ethical dilemmas we encountered when implementing coteaching in a secondary science education program. Although the respondents addressed this issue, they also raised other important points pertaining to their own experiences with implementing and researching coteaching. In this paper, we synthesize these perspectives and further discuss the implications of implementing coteaching. URN: urn:nbn:de:0114-fqs0604239

The Reflexive Nature of Reading as Ethnographic Practice: Editorial Note

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Wolff-Michael Roth

2004-01-01

Full Text Available In this editorial, I suggest that not only is reading published texts a way of doing ethno­graph­ic research, but also reading concretely realizes itself in the productions of new texts that reproduce the cultural practices that are analyzed in the published text. Reading as ethnographic method is therefore a reflexive project. I provide a dialectical framework for theorizing the reflexive nature of reading. URN: urn:nbn:de:0114-fqs0401390

Review: Dirk Tänzler, Hubert Knobloch & Hans-Georg Soeffner (Eds. (2006. Neue Perspektiven der Wissenssoziologie [New Perspectives on the Sociology of Knowledge

Directory of Open Access Journals (Sweden)

Torsten Junge

2008-10-01

Full Text Available The 14 articles in this collection present theories, questions and research areas in German sociology of knowledge. The contributions analyze the construction of reality with regard to knowledge. As a science of "the real," sociology of knowledge gains access to other disciplines such as ethnology, systems theory, communication studies or cognitive science. The collection emphasizes a critical approach to the possibilities and capacities of sociology of knowledge as such. URN: urn:nbn:de:0114-fqs0901278

OYETOLA, OK

African Journals Online (AJOL)

ADOWIE PERE

2018-03-23

Mar 23, 2018 ... March 2018. Full-text Available ... performance of the controller depends on numerical value of koln .More so ... such as data mining, big data, database management system, data ... Institute for Advanced Study.”, presented a.

A syringe-sharing model for the spread of HIV: application to Omsk, Western Siberia.

Science.gov (United States)

Artzrouni, Marc; Leonenko, Vasiliy N; Mara, Thierry A

2017-03-01

A system of two differential equations is used to model the transmission dynamics of human immunodeficiency virus between 'persons who inject drugs' (PWIDs) and their syringes. Our vector-borne disease model hinges on a metaphorical urn from which PWIDs draw syringes at random which may or may not be infected and may or may not result in one of the two agents becoming infected. The model's parameters are estimated with data mostly from the city of Omsk in Western Siberia. A linear trend in PWID prevalence in Omsk could only be fitted by considering a time-dependent version of the model captured through a secular decrease in the probability that PWIDs decide to share a syringe. A global sensitivity analysis is performed with 14 parameters considered random variables in order to assess their impact on average numbers infected over a 50-year projection. With obvious intervention implications the drug injection rate and the probability of syringe-cleansing are the only parameters whose coefficients of correlations with numbers of infected PWIDs and infected syringes have an absolute value close to or larger than 0.40. © The authors 2015. Published by Oxford University Press on behalf of the Institute of Mathematics and its Applications. All rights reserved.

Review: Giampietro Gobo (2008. Doing Ethnography

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Stefan Thomas

2010-03-01

Full Text Available Doing Ethnography, by Giampietro GOBO, provides an introduction into ethnography from a practice perspective. The author discusses central topics, definitions, procedures, and reflections on the research process. The book thereby offers a thorough overview of the academic discourse on ethnographic research methods, along with a general outlook on recent developments at the cutting edge of methodological trends. Ethnography is elaborated through the integration of method into a constructivist research perspective. URN: urn:nbn:de:0114-fqs1002234

Doing Science—Doing Gender. The Making and the Unmaking of Scientists

Directory of Open Access Journals (Sweden)

Sandra Beaufaÿs

2004-05-01

Full Text Available Reasons for the marginalization of women in science cannot exclusively be found in the abstract sphere of cultural dispositions, but also in the concrete everyday practice of science itself. In her dissertation the author uses Pierre BOURDIEU's concept of the "scientific field" and empirical constructivist methods to examine the mechanisms responsible for successive and systematic exclusion of women from science particularly at higher levels of the career ladder in universities. URN: urn:nbn:de:0114-fqs0402109

I'm OK, Are You Y2K OK?

Science.gov (United States)

Wilson, Thomas F.

1999-01-01

Y2K problems include software programming issues involving chronology and microchips embedded in every conceivable piece of electronic equipment. Procrastination is not in schools' best interest. Administrators should initiate five conversion stages: awareness, assessment, renovation, validation, and implementation. A sample equipment checklist…

Comparing ordinary kriging and inverse distance weighting for soil as pollution in Beijing.

Science.gov (United States)

Qiao, Pengwei; Lei, Mei; Yang, Sucai; Yang, Jun; Guo, Guanghui; Zhou, Xiaoyong

2018-06-01

Spatial interpolation method is the basis of soil heavy metal pollution assessment and remediation. The existing evaluation index for interpolation accuracy did not combine with actual situation. The selection of interpolation methods needs to be based on specific research purposes and research object characteristics. In this paper, As pollution in soils of Beijing was taken as an example. The prediction accuracy of ordinary kriging (OK) and inverse distance weighted (IDW) were evaluated based on the cross validation results and spatial distribution characteristics of influencing factors. The results showed that, under the condition of specific spatial correlation, the cross validation results of OK and IDW for every soil point and the prediction accuracy of spatial distribution trend are similar. But the prediction accuracy of OK for the maximum and minimum is less than IDW, while the number of high pollution areas identified by OK are less than IDW. It is difficult to identify the high pollution areas fully by OK, which shows that the smoothing effect of OK is obvious. In addition, with increasing of the spatial correlation of As concentration, the cross validation error of OK and IDW decreases, and the high pollution area identified by OK is approaching the result of IDW, which can identify the high pollution areas more comprehensively. However, because the semivariogram constructed by OK interpolation method is more subjective and requires larger number of soil samples, IDW is more suitable for spatial prediction of heavy metal pollution in soils.

Oxford Knee Score: cross-cultural adaptation and validation of the Turkish version in patients with osteoarthritis of the knee.

Science.gov (United States)

Tuğay, Baki Umut; Tuğay, Nazan; Güney, Hande; Kınıklı, Gizem İrem; Yüksel, İnci; Atilla, Bülent

2016-01-01

The Oxford Knee Score (OKS) is a valid, short, self-administered, and site- specific outcome measure specifically developed for patients with knee arthroplasty. This study aimed to cross-culturally adapt and validate the OKS to be used in Turkish-speaking patients with osteoarthritis of the knee. The OKS was translated and culturally adapted according to the guidelines in the literature. Ninety-one patients (mean age: 55.89±7.85 years) with knee osteoarthritis participated in the study. Patients completed the Turkish version of the Oxford Knee Score (OKS-TR), Short-Form 36 Health Survey (SF-36), and Western Ontario and McMaster Universities Index (WOMAC) questionnaires. Internal consistency was tested using Cronbach's α coefficient. Patients completed the OKS-TR questionnaire twice in 7 days to determine the reproducibility. Correlation between the total results of both tests was determined by Spearman's correlation coefficient and intraclass correlation coefficients (ICC). Validity was assessed by calculating Spearman's correlation coefficient between the OKS, WOMAC, and SF-36 scores. Floor and ceiling effects were analyzed. Internal consistency was high (Cronbach's α: 0.90). The reproducibility tested by 2 different methods showed no significant difference (p>0.05). The construct validity analyses showed a significant correlation between the OKS and the other scores (p<0.05). There was no floor or ceiling effect in total OKS score. The OKS-TR is a reliable and valid measure for the self-assessment of pain and function in Turkish-speaking patients with osteoarthritis of the knee.

Wangshangkia, a new Devonian ostracod genus from Dushan of Guizhou, South China

Science.gov (United States)

Song, Junjun; Gong, Yiming

2018-02-01

Wangshangkia, a new genus of Ostracoda, from the Late Devonian in Dushan of Guizhou, South China, is described. This genus belongs to the family Bairdiocyprididae Shaver, 1961 and includes two new species, i.e. Wangshangkia dushaniensis and W. bailouiensis. The new genus is characterized by a wide ventral carina with radial striae. It is reported from the Famennian of South China and disappeared just below the Devonian-Carboniferous boundary. Wangshangkia is essentially a benthic crawler and is restricted to the shallow-marine depositional environment with a low hydrodynamic condition. Wangshangkia: urn:lsid:zoobank.org:act:34BF01D4-D202-492D-8E27-BC508EF7EFFB W. dushaniensis: urn:lsid:zoobank.org:act:D267C362-7510-4D19-996B-EA1848D7D025 W. bailouiensis: urn:lsid:zoobank.org:act:FE988AA0-7363-4D9E-A5AB-1526C8DBCDD9

Behavioural lateralisation in reindeer

Directory of Open Access Journals (Sweden)

Yngve Espmark

2002-06-01

Full Text Available Reindeer (Rangifer tarandus kept in corrals or otherwise forced to clump typically start milling in response to stressing events. This behaviour is generally considered to have an antipredator effect. An inquiry on herd behaviour, to which 35 Norwegian reindeer husbandry districts responded, showed that 32 experienced that corralled rein¬deer consistently circled leftwards, whereas the remaining three reported consistently rightward circling. Regular monitoring of a reindeer herd in central Norway over a two-year period (1993-94, and experimental studies on a fraction of the same herd, revealed the following traits. Free-ranging reindeer showed no right- or left-turning preference during grazing or browsing, but when the reindeer were driven into corrals or forced to clump in the open they invariably rotated leftwards. The circling of corralled reindeer was triggered at an average group size of 20 to 25 animals, apparently independently of the age and sex of the animals. When they dug craters in the snow to reach food, the reindeer used their left foreleg significantly more often than their right. In 23 out of 35 reindeer, the right hemisphere of the brain was heavier than the left. However, in the sample as a whole, the weights of the left and right hemispheres did not differ significantly. Lateralised behaviour in reindeer is thought to be determined by natural and stress induced asymmetries in brain structure and hormonal activity. In addition, learning is probably important for passing on the behaviour between herd members and generations. Differences in lateralised behaviour between nearby herds are thought to be related primarily to different exposure to stress and learning, whereas genetical and environmental fac¬tors (e.g. diet, age structure and sex ratio are probably more important for explaining differences between distant pop¬ulations.

Confinement properties of 2D porous molecular networks on metal surfaces

International Nuclear Information System (INIS)

Müller, Kathrin; Enache, Mihaela; Stöhr, Meike

2016-01-01

Quantum effects that arise from confinement of electronic states have been extensively studied for the surface states of noble metals. Utilizing small artificial structures for confinement allows tailoring of the surface properties and offers unique opportunities for applications. So far, examples of surface state confinement include thin films, artificial nanoscale structures, vacancy and adatom islands, self-assembled 1D chains, vicinal surfaces, quantum dots and quantum corrals. In this review we summarize recent achievements in changing the electronic structure of surfaces by adsorption of nanoporous networks whose design principles are based on the concepts of supramolecular chemistry. Already in 1993, it was shown that quantum corrals made from Fe atoms on a Cu(1 1 1) surface using single atom manipulation with a scanning tunnelling microscope confine the Shockley surface state. However, since the atom manipulation technique for the construction of corral structures is a relatively time consuming process, the fabrication of periodic two-dimensional (2D) corral structures is practically impossible. On the other side, by using molecular self-assembly extended 2D porous structures can be achieved in a parallel process, i.e. all pores are formed at the same time. The molecular building blocks are usually held together by non-covalent interactions like hydrogen bonding, metal coordination or dipolar coupling. Due to the reversibility of the bond formation defect-free and long-range ordered networks can be achieved. However, recently also examples of porous networks formed by covalent coupling on the surface have been reported. By the choice of the molecular building blocks, the dimensions of the network (pore size and pore to pore distance) can be controlled. In this way, the confinement properties of the individual pores can be tuned. In addition, the effect of the confined state on the hosting properties of the pores will be discussed in this review article

Spatiotemporal modeling of PM2.5 concentrations at the national scale combining land use regression and Bayesian maximum entropy in China.

Science.gov (United States)

Chen, Li; Gao, Shuang; Zhang, Hui; Sun, Yanling; Ma, Zhenxing; Vedal, Sverre; Mao, Jian; Bai, Zhipeng

2018-05-03

Concentrations of particulate matter with aerodynamic diameter Bayesian Maximum Entropy (BME) interpolation of the LUR space-time residuals were developed to estimate the PM 2.5 concentrations on a national scale in China. This hybrid model could potentially provide more valid predictions than a commonly-used LUR model. The LUR/BME model had good performance characteristics, with R 2  = 0.82 and root mean square error (RMSE) of 4.6 μg/m 3 . Prediction errors of the LUR/BME model were reduced by incorporating soft data accounting for data uncertainty, with the R 2 increasing by 6%. The performance of LUR/BME is better than OK/BME. The LUR/BME model is the most accurate fine spatial scale PM 2.5 model developed to date for China. Copyright © 2018. Published by Elsevier Ltd.

Case study of ILVA, Italy:The impact of failing to consider sustainability as a driver of business model evolution

OpenAIRE

Tonelli, Flavio; Short, Samuel; Taticchi, Paolo

2013-01-01

Part of: Seliger, Günther (Ed.): Innovative solutions : proceedings / 11th Global Conference on Sustainable Manufacturing, Berlin, Germany, 23rd - 25th September, 2013. - Berlin: Universitätsverlag der TU Berlin, 2013. - ISBN 978-3-7983-2609-5 (online). - http://nbn-resolving.de/urn:nbn:de:kobv:83-opus4-40276. - pp. 25–30. The case of ILVA steel works in Taranto, Italy demonstrates the potential impacts associated with failing toadequately consider environmental and social sustainabilit...

History and Psychology—Oral History and Psychoanalysis. Development of a Problematic Relationship. Outline and Literature Survey

Directory of Open Access Journals (Sweden)

Alexander von Plato

2004-01-01

Full Text Available The article is about the relationship between two scientific fields—history and psychology—with a focus on their connections during the last 150 years and about the meaning of subjectivity in history. It addresses possibilities of cooperation, taking as an example the relationship of oral history and psychoanalysis. The article emphasizes the problems regarding unconscious elements in history as well as the perception and "digestion" of history by the individual and the collective memory. URN: urn:nbn:de:0114-fqs0401181

Creating Collaborative Third-space Discourse to Address Contradictions in Coteaching

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Ed Lehner

2006-09-01

Full Text Available This article examines how coteaching can be wrought with contradictions without employing its recursive counterpart, cogenerative dialogue. To help avoid dualistic tendencies while coteaching, participants can use cogenerative dialogue to help create collaborative third-space discourse where plans of cooperative action can be cogenerated. This work also shares how the extension of the cosmopolitan ethic can be used in tandem with one-on-one cogenerative dialogues to navigate ideological differences in coteachers and create fruitful working partnerships. URN: urn:nbn:de:0114-fqs0604198

Review: Lesa Lockford (2004. Performing Femininity: Rewriting Gender Identity

Directory of Open Access Journals (Sweden)

Mary Gergen

2006-03-01

Full Text Available Performing Femininity is composed of a series of performances presented by the author to a varied audience, from customers at a strip club in New Orleans to a university class, in which a feminist history "Spin the Bottle" game was an integral part. Challenging the dominant discourse of feminist theorists, LOCKFORD looks for strength and liberatory possibilities in what appear to be forms of abjection. Traditional topics of embodiment are rediscovered in this provocative book. URN: urn:nbn:de:0114-fqs0602130

Genetic analysis of the spindle checkpoint genes san-1, mdf-2, bub-3 and the CENP-F homologues hcp-1 and hcp-2 in Caenorhabditis elegans

Directory of Open Access Journals (Sweden)

Moore Landon L

2008-02-01

Full Text Available Abstract Background The spindle checkpoint delays the onset of anaphase until all sister chromatids are aligned properly at the metaphase plate. To investigate the role san-1, the MAD3 homologue, has in Caenorhabditis elegans embryos we used RNA interference (RNAi to identify genes synthetic lethal with the viable san-1(ok1580 deletion mutant. Results The san-1(ok1580 animal has low penetrating phenotypes including an increased incidence of males, larvae arrest, slow growth, protruding vulva, and defects in vulva morphogenesis. We found that the viability of san-1(ok1580 embryos is significantly reduced when HCP-1 (CENP-F homologue, MDF-1 (MAD-1 homologue, MDF-2 (MAD-2 homologue or BUB-3 (predicted BUB-3 homologue are reduced by RNAi. Interestingly, the viability of san-1(ok1580 embryos is not significantly reduced when the paralog of HCP-1, HCP-2, is reduced. The phenotype of san-1(ok1580;hcp-1(RNAi embryos includes embryonic and larval lethality, abnormal organ development, and an increase in abnormal chromosome segregation (aberrant mitotic nuclei, anaphase bridging. Several of the san-1(ok1580;hcp-1(RNAi animals displayed abnormal kinetochore (detected by MPM-2 and microtubule structure. The survival of mdf-2(RNAi;hcp-1(RNAi embryos but not bub-3(RNAi;hcp-1(RNAi embryos was also compromised. Finally, we found that san-1(ok1580 and bub-3(RNAi, but not hcp-1(RNAi embryos, were sensitive to anoxia, suggesting that like SAN-1, BUB-3 has a functional role as a spindle checkpoint protein. Conclusion Together, these data suggest that in the C. elegans embryo, HCP-1 interacts with a subset of the spindle checkpoint pathway. Furthermore, the fact that san-1(ok1580;hcp-1(RNAi animals had a severe viability defect whereas in the san-1(ok1580;hcp-2(RNAi and san-1(ok1580;hcp-2(ok1757 animals the viability defect was not as severe suggesting that hcp-1 and hcp-2 are not completely redundant.

[Control of Chagas' disease in Guarani communities: knowledge and hygiene habits within the Project to Improve Living Conditions in Bolivia].

Science.gov (United States)

Verdú, J; Ruiz, M T

2003-01-01

The aim of this study was to identify knowledge and control of vectorial transmission (Triatoma infestans, known as vinchuca) of Chagas' disease in Guaraní Communities in Bolivia. We performed a descriptive study of a series of 98 individuals through a semi-structured questionnaire. Interviewees were asked about their familiarity with vinchuca, whether they thought vinchuca produced disease, the name of the disease and its consequences, as well as behavior related to eliminating the domestic insect vectors, such as cleaning of the home, backyard and corral.The insect vector was sufficiently well known (98%), although the name of the disease was identified by only 14.3% of the interviewees. Although the dwellings favored insect proliferation, they were not frequently cleaned: 28.6% cleaned their homes while and 42.9% cleaned the backyard and 7.1% cleaned the corral. Gender differences were found in the division of labor: women cleaned the homes and backyards, while men clean the corral. Experience has shown that the usefulness of projects for building healthy living areas and for health education depends on the value given to these projects by the community. Women are probably the best target group, because they perform a greater number of preventive tasks and seldom leave the community for extended periods of time.

Control del Chagas en comunidades guaraníes: conocimiento y hábitos higiénicos dentro del Proyecto de Mejoramiento de Viviendas en Bolivia

Directory of Open Access Journals (Sweden)

Verdú J.

2003-01-01

Full Text Available El objetivo fue identificar el conocimiento y control del vector (Triatoma infestans transmisor de la enfermedad de Chagas en comunidades guaraníes de Bolivia, conocido como vinchuca. Se trata de un estudio descriptivo de una serie de 98 casos mediante cuestionario semiestructurado sobre: conocimiento de la vinchuca, si produce alguna enfermedad, nombre de la enfermedad y sus consecuencias, así como las conductas de higiene: patio, vivienda, corrales. La vinchuca fue suficientemente conocida (98%, aunque sólo el 14,3% identificó el nombre de la enfermedad. Pese a ser ambientes apropiados para la proliferación de vinchucas, se limpian con poca frecuencia: el 28,6% limpia la vivienda, el 42,9% el patio y el 7,1% el corral. Se evidencia una división sexual del trabajo: mientras las mujeres limpian la vivienda y el patio, los varones limpian los corrales. La experiencia enseña el valor del proyecto de construcción de viviendas saludables y educación para la salud en la medida en que la comunidad los valora. Probablemente, las mujeres son el mejor grupo destinatario, pues realizan más tareas preventivas y no se ausentan con tanta frecuencia de la comunidad.

A new power mapping method based on ordinary kriging and determination of optimal detector location strategy

International Nuclear Information System (INIS)

Peng, Xingjie; Wang, Kan; Li, Qing

2014-01-01

Highlights: • A new power mapping method based on Ordinary Kriging (OK) is proposed. • Measurements from DayaBay Unit 1 PWR are used to verify the OK method. • The OK method performs better than the CECOR method. • An optimal neutron detector location strategy based on ordinary kriging and simulated annealing is proposed. - Abstract: The Ordinary Kriging (OK) method is presented that is designed for a core power mapping calculation of pressurized water reactors (PWRs). Measurements from DayaBay Unit 1 PWR are used to verify the accuracy of the OK method. The root mean square (RMS) reconstruction errors are kept at less than 0.35%, and the maximum reconstruction relative errors (RE) are kept at less than 1.02% for the entire operating cycle. The reconstructed assembly power distribution results show that the OK method is fit for core power distribution monitoring. The quality of power distribution obtained by the OK method is partly determined by the neutron detector locations, and the OK method is also applied to solve the optimal neutron detector location problem. The spatially averaged ordinary kriging variance (AOKV) is minimized using simulated annealing, and then, the optimal in-core neutron detector locations are obtained. The result shows that the current neutron detector location of DayaBay Unit 1 reactor is near-optimal

Ultimate pH values and bacteriological condition of meat and stress metabolites in blood of transported reindeer bulls

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E. Wiklund

2001-03-01

Full Text Available Twenty-three reindeer bulls, aged 2-3 years, fed during two winter months at the Vuolda reindeer research station in Arjeplog, Sweden, were used in the study. The first group of eight reindeer was moved from their feeding corral to a selection corral, captured by lasso and stunned with a captive bolt outside the selection corral. The second group of seven reindeer was moved to the selection corral, captured by lasso and restrained, after which they were loaded onto a lorry- and transported for 1 hour and then slaughtered. The third group of eight reindeer was moved to the selection corral and herded directly onto the lorry, without any manual handling. They were transported for 5 h and then slaughtered. In both transport groups, four reindeer were fitted with pre-programmed automatic blood sampling equipment (ABSE. ABSE sampled blood at predetermined times via a jugular vein catheter. Ultimate pH-values in three muscles (Mm. longissimus, triceps brachii and biceps femoris were significantly lower in the group carefully handled and transported for 5 h compared with the other two groups. The physiological mechanisms behind these results are discussed. Samples from M. semimembranosus were collected at slaughter and after 2, 6 and 10 days of refrigerated storage (+4 °C. The samples were analysed for total counts of aerobic bacteria (pour-plated in Tryptone Glucose Extract Agar, Difco, incubated at 20 °C and 30 °C, respectively for 72 h, coliform bacteria 37 °C (pour-plated in Violet Red Bile Agar, Oxoid, incubated at 37 °C for 24 h, Enterococci (surface-plated onto Slantez and Bartley Agar, Oxoid, incubated at 44 °C for 48 h and Bacillus cereus (surface-plated onto Blood Agar Plates (Blood Agar Base, Difco, supplemented with 5% defibrinated horse blood 30 °C for 24 h. All samples fell in the range 'fit for consumption'. At slaughter, there was no difference in ASAT activity, urea and Cortisol concentrations between the two transported groups

Astronomers Use Moon in Effort to Corral Elusive Cosmic Particles

Science.gov (United States)

2010-11-01

Seeking to detect mysterious, ultra-high-energy neutrinos from distant regions of space, a team of astronomers used the Moon as part of an innovative telescope system for the search. Their work gave new insight on the possible origin of the elusive subatomic particles and points the way to opening a new view of the Universe in the future. The team used special-purpose electronic equipment brought to the National Science Foundation's Very Large Array (VLA) radio telescope, and took advantage of new, more-sensitive radio receivers installed as part of the Expanded VLA (EVLA) project. Prior to their observations, they tested their system by flying a small, specialized transmitter over the VLA in a helium balloon. In 200 hours of observations, Ted Jaeger of the University of Iowa and the Naval Research Laboratory, and Robert Mutel and Kenneth Gayley of the University of Iowa did not detect any of the ultra-high-energy neutrinos they sought. This lack of detection placed a new limit on the amount of such particles arriving from space, and cast doubt on some theoretical models for how those neutrinos are produced. Neutrinos are fast-moving subatomic particles with no electrical charge that readily pass unimpeded through ordinary matter. Though plentiful in the Universe, they are notoriously difficult to detect. Experiments to detect neutrinos from the Sun and supernova explosions have used large volumes of material such as water or chlorine to capture the rare interactions of the particles with ordinary matter. The ultra-high-energy neutrinos the astronomers sought are postulated to be produced by the energetic, black-hole-powered cores of distant galaxies; massive stellar explosions; annihilation of dark matter; cosmic-ray particles interacting with photons of the Cosmic Microwave Background; tears in the fabric of space-time; and collisions of the ultra-high-energy neutrinos with lower-energy neutrinos left over from the Big Bang. Radio telescopes can't detect

An Interdisciplinary Approach to Complexity: Migratory Decisions of Iranians in Vienna

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Julia Czarnowski

2009-07-01

Full Text Available Iranians have come to Austria for a multitude of stated reasons. Within this paper the two authors follow their Iranian migrant interviewees' reasoning with two very different styles of analysis, each steaming from a particular scientific background. While Sociologist FLIEGENSCHNEE emphasizes schematic groupings with reference to push and pull factors, for Cultural Anthropologist CZARNOWSKI the interwovenness/interaction of these factors is more important. Together both develop a specific methodology of how to approach interview analysis with regard to migratory decision-making. URN: urn:nbn:de:0114-fqs090396

Memory and Culture—Notes on the Concept of "Memory Cultures" Within Cultural Studies

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Nina Leonhard

2007-09-01

Full Text Available This book of collected papers, published by the DFG-Sonderforschungsbereich Erinnerungskulturen ("Memory Cultures" at the Justus Liebig University of Gießen, gives a broad overview of approaches and results of memory research within various disciplines. Despite many interesting insights, the book offers no general framework by which the different aspects analyzed by the authors could be classified and related to one another. Thus, the shortcomings of memory studies, from a cultural perspective and understood as an interdisciplinary, multidimensional research program, become visible. URN: urn:nbn:de:0114-fqs0703259

Online Qualitative Research in the Age of E-Commerce: Data Sources and Approaches

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Nikhilesh Dholakia

2004-05-01

Full Text Available With the boom in E-commerce, practitioners and researchers are increasingly generating marketing and strategic insights by employing the Internet as an effective new tool for conducting well-established forms of qualitative research (TISCHLER 2004. The potential of Internet as a rich data source and an attractive arena for qualitative research in e-commerce settings—in other words cyberspace as a "field," in the ethnographic sense—has not received adequate attention. This paper explores qualitative research prospects in e-commerce arenas. URN: urn:nbn:de:0114-fqs0402299

Introduction: Qualitative Research in Criminology

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Michael Meuser

2002-01-01

Full Text Available This paper begins with a brief overview of research traditions that paved the way for qualitative methods in criminological research (labeling approach and critical criminology. In addition, it outlines recent trends in qualitative criminology. The potentials and the limits of a perspective of "understanding from within" ("Verstehen" on deviance and social control are discussed. The contributions to the volume—examples of qualitative criminological research from German speaking countries—are introduced in reference to some current trends of conceptual and methodological discussions in criminology. URN: urn:nbn:de:0114-fqs0201129

Review: Melanie Mauthner, Maxine Birch, Julie Jessop & Tina Miller (Eds. (2002. Ethics in Qualitative Research

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Mechthild Kiegelmann

2004-01-01

Full Text Available This book is a collection of theoretical thoughts about ethics in qualitative research. A coherent group of feminists propose issues to consider in research from a perspective of an ethics of care. The authors illustrate their argu­ments with examples from their own research ex­peri­ences. Examples from actual research, e.g. in the area of health studies are provided. This book is well suited for graduate students to learn about ethics in qualitative research. URN: urn:nbn:de:0114-fqs0401276

Program Analysis and Its Relevance for Educational Research

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Bernd Käpplinger

2008-01-01

Full Text Available Program analyses are frequently used in research on continuing education. The use of such analyses will be described in this article. Existing data sources, research topics, qualitative, quantitative and mixed methods, will be discussed. Three types of program analysis will be developed. The article ends with a discussion of the advantages and disadvantages of program analysis in contrast to questionnaires. Future developments and challenges will be sketched in the conclusion. Recommendations for the future development of program analysis will be given. URN: urn:nbn:de:0114-fqs0801379

Conducting an Unplanned Participant Observation: The Case of a Non-Birder in Bird Watchers' Land

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Roni Berger

2016-12-01

Full Text Available This article describes two participant observations of birdwatchers, which occurred by serendipity. Characteristics of personal and interpersonal behavior patterns are identified and illustrated. Specifically, four themes including total immersion and dedication to details of birders as well the collaborative-competitive nature of their interactions and sub-culture are discussed in the context of available knowledge about subcultures in other types of sports and leisure activities. Methodological and ethical aspects of unplanned participant observation are also addressed. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs170187

Review: Oliver Märker & Matthias Trénel (Eds. (2003. Online-Mediation. Neue Medien in der Konfliktvermittlung – mit Beispielen aus Politik und Wirtschaft [Online-Mediation. New Media in Conflict Resolution—with Examples from Politics and Industry

Directory of Open Access Journals (Sweden)

Nicola Döring

2004-01-01

Full Text Available Online-Mediation deals with conflict resolution methods that are carried out partially or completely online. The book analyses online mediation as a socio-technical system through the means of the computer-based technological platform deeply interwoven with conflict-related social communication. The first part of the book discusses the multiple options and restrictions of online communication in moderation and mediation processes. For example, one advantage of online mediation is that geographically separated parties (e.g. in e-commerce settings can resolve conflicts at comparatively low cost. The second part of the book reports online mediation examples from politics and industry. Although online mediation is described as a seminal method increasingly requested, several socio-technical problems need to be addressed by further research. The book provides an informative view of the subject, focusing on the German-speaking countries. Unfortunately, it lacks a systematic comparison of different online mediation tools and techniques as well as a closer look at the business models and professional issues in this new field of activity. URN: urn:nbn:de:0114-fqs040168

Review Essay: Situational Analysis—Strauss Meets Foucault?

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Rainer Diaz-Bone

2012-11-01

Full Text Available With the (German translation of the volume "Situational Analysis" by Adele CLARKE, a new approach to the development of Grounded Theory Methodology (GTM is presented. CLARKE radicalizes the methodological standpoint of classical pragmatism. She integrates structuralist and post-structuralist analytic elements into GTM. This review essay critically analyzes this new integration and employs the methodological notion of the "theory/methods package" introduced by CLARKE, which denotes the cohesion of theory, methodology and methods, and can be conceived as a kind of “methodic holism” (not to be confused with the different concept of methodological holism. CLARKE puts more emphasis on objects and power than classical GTM, and attempts to integrate a FOUCAULTian discourse model. However, she does not succeed in integrating the pragmatic and structuralist/post-structuralist methodologies in a fully coherent way. Her situational analysis does not incorporate a discourse-analytic methodology, and has not implemented the methods needed for a FOUCAULTian discourse analysis. Nevertheless, this valuable work presents an important development in pragmatic social research. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1301115

Don't Blame the Software: Using Qualitative Data Analysis Software Successfully in Doctoral Research

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Michelle Salmona

2016-07-01

Full Text Available In this article, we explore the learning experiences of doctoral candidates as they use qualitative data analysis software (QDAS. Of particular interest is the process of adopting technology during the development of research methodology. Using an action research approach, data was gathered over five years from advanced doctoral research candidates and supervisors. The technology acceptance model (TAM was then applied as a theoretical analytic lens for better understanding how students interact with new technology. Findings relate to two significant barriers which doctoral students confront: 1. aligning perceptions of ease of use and usefulness is essential in overcoming resistance to technological change; 2. transparency into the research process through technology promotes insights into methodological challenges. Transitioning through both barriers requires a competent foundation in qualitative research. The study acknowledges the importance of higher degree research, curriculum reform and doctoral supervision in post-graduate research training together with their interconnected relationships in support of high-quality inquiry. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1603117

Triangulation of Qualitative Methods for the Exploration of Activity Systems in Ergonomics

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Monika Hackel

2008-08-01

Full Text Available Research concerning ergonomic issues in interdisciplinary projects often raises several very specific questions depending on project objectives. To answer these questions the application of research methods should be thoroughly considered, regarding both the expenditure and the options within the scope of the given resources. The project AQUIMO develops an adaptable modelling tool for mechatronical engineering and creates a related qualification program. The task of social scientific research within this project is to identify requirements viewed from the perspective of the subsequent users. This formative evaluation is based on the approach of "developmental work research" as set forth by ENGESTRÖM and, thus, is a form of "action research". This paper discusses the triangulation of several qualitative methods addressing the examination of difficulties in interdisciplinary collaboration in mechatronical engineering. After a description of both background and analytic approach within the project AQUIMO, the methods are briefly described concerning their advantages and critical points. Their application within the research project AQUIMO is explained from an activity theoretical perspective. URN: urn:nbn:de:0114-fqs0803158

"Doing pupil" nach Schulschluss – Videografie an einer Kinderuniversität

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Alexandra König

2015-03-01

Full Text Available Auf der Basis einer Videografie an einer Kinderuniversität wird in dem vorliegenden Beitrag die Frage verfolgt, wie an einem außerschulischen Lernort generationale Ordnung hergestellt wird und welche Gestalt diese annimmt. Als heuristischer Rahmen dient das Modell der "Sozialisation als generationales Ordnen" (BÜHLER-NIEDERBERGER 2011; BÜHLER-NIEDERBERGER & TÜRKYILMAZ 2014. Die Analyse der ersten Sitzungen von zwei kontrastiven Kursen an der Kinder- und Jugenduniversität zeigt erstens, wie Kinder struktursensitiv Regeln in dem unbekannten Kontext erspüren, erarbeiten und modifizieren, wie sie KomplizInnen in der Herstellung generationaler Ordnung sind. Zweitens wird die Dominanz der schulischen Ordnung und des SchülerInnenstatus für Kindheit deutlich. Die Kinder stellen "Schule" her – paradoxerweise auch in einem außerschulischen Kontext. Drittens wird im kontrastiven Vergleich der untersuchten Kurse eine Varianz dieser Ordnungen – in Bezug auf die Form des Wissens und Adressierung der Kinder – herausgearbeitet, die allerdings die Dominanz der schulischen Ordnung nicht bricht. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs150263

School-to-Work-Transition—Career Development and Family Planning: Methodological Guidelines and Challenges of a Qualitative Longitudinal Panel-Study

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Thomas Kühn

2000-06-01

Full Text Available We are presenting the basic features of our qualitative German panel study concerning the job entry of young adults, dealing also with methodological issues. The selection of the respondents in qualified jobs (commercial-technical, crafts/trade, services took into account gender-specific aspects, different labor-market prospects and regions. From the quantitative panel, a theoretical sample of respondents was selected who were interviewed three times in three-years intervals (3 waves. These interviews, focusing on individual biographies (i.e. orientations and action strategies form the basis for constructing a typology. Methodological innovations concern the modeling of the sequence of occupational actions and orientations as life-course sequences and the case-specific and case-comparing analysis of interview transcripts. This was done—based on a data bank containing the interview material—by means of a detailed scheme of categories. The integration of quantitative and qualitative longitudinal data presents a theoretical and methodological challenge. Our focus is on biography and life-course research which suggests an interdisciplinary approach. URN: urn:nbn:de:0114-fqs0002178

BAZI YENİ İLAÇ ÖNCÜSÜ BENZOTİYAZOLİNON TÜREVLERİ ÜZERİNE ÇOK DEĞİŞKENLİ SAR ÇALIŞMALARI

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Yadigar Gülseven Sıdır

2015-12-01

Full Text Available Yeni modellenen analjezik aktif otuziki benzotiyazolinon türevinin çok değişkenli yapı-aktivite ilişkileri iki farklı kemometric metot olan temel bileşen analizi (PCA ve hiyerarşik kümeleme analizi (HCA kullanılarak incelendi. Moleküllerin elektronik, termokimyasal ve hidrofobik özelliklerini tanımlayan yirmi moleküler tanımlayıcı Austin Modeli (AM1 ve yoğunluk fonksiyonel teorisi (DFT kullanılarak hesaplandı. HCA ve PCA metotları sıvı fazdaki (HOFSıvı polarizebilite (α, elektrofilik indis (ω ve oluşum ısısı ile uygulanır. Sonuçlar otuziki molekülü aktifve inaktif olarak iki grupta sınıflandırmak için oldukça etkili bulundu. Korelasyon matrisi ve değişken ağırlığı moleküllerin hesaplanan fizikokimyasal parametreleri arasındaki ilişkileri açıklamak için kullanıldı. İncelenen bileşiklerin ana halkasına F ve OCH3 sübstitüentlerin eklenmesi ve piperazin üzerindeki alkil gurubunun uzaması biyolojik aktiviteyi değiştir.

How to decide the optimal scheme and the optimal time for construction

International Nuclear Information System (INIS)

Gjermundsen, T.; Dalsnes, B.; Jensen, T.

1991-01-01

Since the development in Norway began some 105 years ago the mean annual generation has reached approximately 110 TWh. This means that there is a large potential for uprating and refurbishing (U/R). A project undertaken by the Norwegian Water Resources and Energy Administration (NVE) has identified energy resources by means of U/R to about 10 TWh annual generation. One problem in harnessing the potential owned by small and medium sized electricity boards is the lack of simple tools to help us carry out the right decisions. The paper describes a simple model to find the best solution of scheme and the optimal time to start. The principle of present value is used. The main input is: production, price, annual costs of maintenance, the remaining lifetime and the social rate of return. The model calculates the present value of U/R/N for different points of time to start U/R/N. In addition the present value of the existing plant is calculated. Several alternatives can be considered. The best one will be the one which gives the highest present value according to the value of the existing plant. The internal rate of return is also calculated. To be aware of the sensitivity a star diagram is shown. The model gives the opportunity to include environmental charges and the value of effect (peak power). (Author)

The reindeer abomasal nematode (Ostertagia gruehneri) is naturally transmitted to sheep when sharing pastures

DEFF Research Database (Denmark)

Manninen, Saana-Maaria; Thamsborg, Stig Milan; Laaksonen, Sauli

2014-01-01

The increasing number of sheep (Ovis aries) in northern Finland, often alternately corralled with winter-fed reindeer (Rangifer tarandus tarandus), creates potential for cross-infection of gastrointestinal nematodes. The aim of this study was to elucidate this possibility with 43 animals. Eleven...... reindeer and 8 sheep had shared a corral by turns, reindeer during winters, and sheep in summers. Another 12 reindeer had no known contact with sheep. Twelve sheep had no close contact to other ruminants. Both reindeer groups were free-ranging during summers. During slaughter in September to November, 2003......, abomasa and parts of intestines were collected. Gastrointestinal nematodes were counted and identified. The species found were the following: in reindeer, Ostertagia gruehneri/Ostertagia arctica, Mazamastrongylus dagestanica, Nematodirus tarandi, Nematodirella longissimespiculata and Bunostomum...

Immigration and Citizenship: Participation and Self-organisation of Immigrants in the Veneto (North Italy

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Claudia Mantovan

2006-05-01

Full Text Available The changes related to globalisation and to the increasing presence of immigrants in Western Europe place the traditional concept of citizenship in crisis: formal citizenship is no longer a means to inclusion for an increasing number of people, such as non-EU immigrants. A research project, like the one presented in this paper, which seeks to study immigrants' citizenship demands (MEZZADRA, 2001, needs, therefore, to concentrate on a more pragmatic meaning of citizenship. Partly following the suggestions of some authors who have researched this topic, I have built a multidimensional model for analysing immigrants' self-organisation and political participation in Italy and, in particular, in the Veneto region. The model takes into consideration four factors that can have an influence on immigrants' civic and political participation, namely: 1 supranational and national context, 2 local immigration field, 3 infra-political sphere, cultural background, transnational dimension and 4 some variables related to the individual (like gender, age, length of time in host country, etc. The findings show that these factors are important in shaping "immigrants' citizenship demands" and that for many immigrants formal citizenship is neither a salient issue nor a fundamental tool for participation in the society of arrival. URN: urn:nbn:de:0114-fqs060347

Deformation of the Northwestern Okhotsk Plate: How is it happening?

Science.gov (United States)

Hindle, D.; Fujita, K.; Mackey, K.

2009-09-01

The Eurasia (EU) - North America (NA) plate boundary zone across Northeast Asia still presents many open questions within the plate tectonic paradigm. Constraining the geometry and number of plates or microplates present in the plate boundary zone is especially difficult because of the location of the EU-NA euler pole close to or even upon the EU-NA boundary. One of the major challenges remains the geometry of the Okhotsk plate (OK). whose northwestern portion terminates on the EU-OK-NA triple junction and is thus caught and compressed between converging EU and NA. We suggest that this leads to a coherent and understandable large scale deformation pattern of mostly northwest-southeast trending strike-slip faults which split Northwest OK into several extruding slivers. When the fault geometry is analysed together with space geodetic and focal mechanism data it suggests a central block which is extruding faster bordered east and west by progressively slower extruding blocks until the OK plate boundary faults are encountered. Taking into account elastic loading from both the intra-OK faults and the OK-Pacific (PA) boundary reconciles geodetic motions with geologic slip rates on at least the OK-NA boundary which corresponds to the Ulakhan fault.

Raidpere Veneetsia biennaalile

Index Scriptorium Estoniae

2005-01-01

2005. aastal esindab 51. Veneetsia kunstibiennaalil Eestit fotograaf Mark Raidpere oma väljapanekuga "Varjupaik", mille koostab kunstikriitik Hanno Soans. Kuraatorid Maria Corral (Kunsti kogemus) ja Rosa Martinez (Alati pisut eespool)

Prosthetic alignment after total knee replacement is not associated with dissatisfaction or change in Oxford Knee Score: A multivariable regression analysis.

Science.gov (United States)

Huijbregts, Henricus J T A M; Khan, Riaz J K; Fick, Daniel P; Jarrett, Olivia M; Haebich, Samantha

2016-06-01

Approximately 18% of the patients are dissatisfied with the result of total knee replacement. However, the relation between dissatisfaction and prosthetic alignment has not been investigated before. We retrospectively analysed prospectively gathered data of all patients who had a primary TKR, preoperative and one-year postoperative Oxford Knee Scores (OKS) and postoperative computed tomography (CT). The CT protocol measures hip-knee-ankle (HKA) angle, and coronal, sagittal and axial component alignment. Satisfaction was defined using a five-item Likert scale. We dichotomised dissatisfaction by combining '(very) dissatisfied' and 'neutral/not sure'. Associations with dissatisfaction and change in OKS were calculated using multivariable logistic and linear regression models. 230 TKRs were implanted in 105 men and 106 women. At one year, 12% were (very) dissatisfied and 10% neutral. Coronal alignment of the femoral component was 0.5 degrees more accurate in patients who were satisfied at one year. The other alignment measurements were not different between satisfied and dissatisfied patients. All radiographic measurements had a P-value>0.10 on univariate analyses. At one year, dissatisfaction was associated with the three-months OKS. Change in OKS was associated with three-months OKS, preoperative physical SF-12, preoperative pain and cruciate retaining design. Neither mechanical axis, nor component alignment, is associated with dissatisfaction at one year following TKR. Patients get the best outcome when pain reduction and function improvement are optimal during the first three months and when the indication to embark on surgery is based on physical limitations rather than on a high pain score. 2. Copyright © 2016 Elsevier B.V. All rights reserved.

OnlineMin

DEFF Research Database (Denmark)

Brodal, Gerth Stølting; Moruz, Gabriel; Negoescu, Andrei

2015-01-01

OnlineMin that has optimal competitiveness and allows fast implementations. In fact, if k pages fit in internal memory the best previous solution required O(k2) time per request and O(k) space. We present two implementations of OnlineMin which use O(k) space, but only O(logk) worst case time and O...

Dini ve Kültürel Çoğulculukta Varoluş Mücadelesine Bir Bakış: Malezya Tecrübesi / An Overview towards the Existence Struggle in Religious and Cultural Pluralism: Malaysia Experience

Directory of Open Access Journals (Sweden)

Saim Kayadibi

2016-11-01

Dini ve Kültürel Çoğulculukta Varoluş Mücadelesine Bir Bakış: Malezya Tecrübesi Öz Malezya sosyo-kültürel yapısı itibari ile çok dinli, çok dilli ve çok kültürlü toplumların barış ve huzur içerisinde yaşayabilme özelliğini göstermesinden dolayı birçok ülkeye örnek oluşturabilecek nadide birlikteliklerden biridir. Bu çok kültürlülük, çok dinlilik ve çok dillilik özelliklerini bir zenginlik olarak görüp, birlikte güçlü bir toplum oluşturabilmenin çabası içerisindedir. Birçok sahada, örneğin İslam Ekonomisi ve Bankacılığı, Helal Gıda, modern bir devlette İslam Hukuku kurallarının uygulanabilme özelliğinde öncü rol oynayabilen, hatta merkez ülke olma yarışında ciddi çalışmaları vardır. Tarihi tecrübe açısından Malezya, konum itibariyle ciddi işgallerin merkezi olmuş, birçok sömürge devletinin izlerini atabilmenin, sömürge psikolojisinden kurtulabilmenin, yaralarını sarabilmenin mücadelesini veren bir ülkedir. Geçmişte sömürge ülkelerinden kalan acı hatıraya rağmen Osmanlı devletinden gördüğü kardeş ve dost yardımlar hafızasının derinliklerinde sağlam izler bırakmıştır. Şimdi ise farklı etnik yapısını huzur ve barış içerisinde birlikte götürebilmenin mücadelesini veren ve diğer ülkelere de örnek oluşturabilecek model bir yapıya sahiptir. Bunun yanında Malezya’yı Türkiye ile karşılaştırmaya çalışmak yanlış sonuçlar doğurabilir. Sömürge geçmişi olmayan, gayr-i Müslim nüfusu neredeyse yok denecek kadar az olan Türkiye’nin Malezya ile kıyaslanması düşünülemez. Bu makalemizde çok dinli toplumlarda Müslümanlar incelenirken Malezya örnek olarak alınacak, onların yaşamları, tarihi ve sosyal evreleri, dini hayatın yaşanmasında sorunların olup olmadığı, milli bir bilinç oluşturmak için nasıl bir strateji geliştirildiği, topyekûn bir bakış açısı ile problemlerin neler olduğu ve ne tür �

OnlineMin: A Fast Strongly Competitive Randomized Paging Algorithm

DEFF Research Database (Denmark)

Brodal, Gerth Stølting; Moruz, Gabriel; Negoescu, Andrei

2012-01-01

approach that both has optimal competitiveness and selects victim pages in subquadratic time. In fact, if k pages fit in internal memory the best previous solution required O(k 2) time per request and O(k) space, whereas our approach takes also O(k) space, but only O(logk) time in the worst case per page...

The Deconstructive and Reconstructive Faces of Social Construction: An Interview with Ken Gergen

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César A. Cisneros Puebla

2008-01-01

Full Text Available This conversation is an effort to include new elements in the FQS debate on constructionism. In his eloquent and unambiguous style GERGEN speaks out about critical realism, rationality, truth claims, grounding and other scientific and human beliefs. Firmly based in the constructionist perspective of ethics, GERGEN leads us to examine relevant epistemological questions such as solipsism and the value of prediction, the searching for foundations, and the radical and retro pendulum in the sociology of knowledge. The "conversational reality" performed in this piece is just a small part of our cultural complexity. URN: urn:nbn:de:0114-fqs0801204

Stories Matter: Conceptual Challenges in the Development of Oral History Database Building Software

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Erin Jessee

2010-11-01

Full Text Available Stories Matter is new oral history database building software designed by an interdisciplinary team of oral historians and a software engineer affiliated with the Centre for Oral History and Digital Storytelling at Concordia University in Montreal, Quebec, Canada. It encourages a shift away from transcription, enabling oral historians to continue to interact with their interviews in an efficient manner without compromising the greater life history context of their interviewees. This article addresses some of the conceptual challenges that arose when developing this software. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs110119

The Descendants of Time and the Lodgers of Space: The Life Stories of Teacher Trainees who Immigrated to Israel During the 1990s

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Anat Kainan

2005-09-01

Full Text Available This paper attempts to characterize teacher trainees who immigrated to Israel during the 1990s. The life stories of six students who emi­grated from the Ukraine, Russia, the Georgian Re­pub­lic, Argentina, Chile, and Ethiopia are ana­lyzed. The central finding suggests that their stories are devoid of the human, geographic, and cultural aspects of Israeli society. This finding is surprising because it differs from other studies. We used the Foucauldian concepts of the descendants of time and the lodgers of space for understanding the phenomenon. URN: urn:nbn:de:0114-fqs0503103

Using Qualitative Indicators of Sustainability in Iberoamerican Environmental Research

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José Gutiérrez Pérez

2006-09-01

Full Text Available In this article we include a revision of alternative approaches developed throughout the two last decades in Iberoamerican environmental research and possible implications for the evaluation of sustainable development with qualitative indicators. The standardized use in diplomatic reports and international studies reveals their value and acceptance in communities of experts in different contexts. It is stated that international alliances between countries have brought about important changes, although the new discourses on sustainability leave the responsibility, the control and the design of indicators in a state of confusion. URN: urn:nbn:de:0114-fqs0604338

Conference Report: Readings of Qualitative Research – Methods Workshop

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Lisa Pfahl

2004-05-01

Full Text Available At the workshop, the relationship of poststructuralist and postmodernist social theory to the theoretical and methodological positions of interpretive sociology were discussed. A number of presentations contributed methodological reflections from biographical research and (Foucauldian discourse analysis; others discussed results of the application of discourse analysis and deconstruction in empirical research. All in all, it seems that (German biographical researchers have partly recognized and incorporated deconstructionist critique into their enquiries. The workshop has shown there is still a need for reflection on how poststructuralist strategies can inform empirical projects on a practical level. URN: urn:nbn:de:0114-fqs0402158

Review: Julia Reuter (2011. Geschlecht und Körper: Studien zur Materialität und Inszenierung gesellschaftlicher Wirklichkeit [Gender and Body: Studies on Materiality and Enactment of Social Reality

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Larissa Schindler

2012-03-01

Full Text Available Julia REUTER's latest book, "Geschlecht und Körper" [Gender and Body], contains ten studies on these two central concepts in sociology, as well as lending consideration to visuality and otherness. The author focuses on theories of performance, discourse and practice, which are used both as analytical tools and, reflexively, as objects of analysis. The book offers rich descriptions of the two central concepts, but does not fundamentally deal with how they interrelate. It offers a vivid account of current themes and discussions. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs120268

Risk, Affect and Emotion

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Jens O. Zinn

2006-01-01

Full Text Available For a long time theorising has underestimated the importance of affect and emotion in decision making and the management of risk and uncertainty. In relatively one-sided interpretations emotions were often interpreted as threats for rational decision making, and could be triggered by uncertainties, which would go along with social change. Recent interdisciplinary research has shown the importance to acknowledge the more complex link between reasoning and emotions. The article outlines different perspectives on emotion in risk research of economics, psychology and sociology and argues for further research. URN: urn:nbn:de:0114-fqs0601293

Editorial: Qualitative Research and Intercultural Communication

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Matthias Otten

2009-01-01

Full Text Available This article introduces to the thematic scope and the articles of this special issue and it explains some important terminological distinctions of the intercultural research field. The overall aim of this issue is to explore the manifold ways to apply and to reflect upon qualitative research methods in the context of intercultural communication. This implies both a discussion of genuine characteristics of intercultural qualitative research as well as attempts to identify common features and linkages of this special area with more general interpretative research traditions under the "umbrella" of qualitative social research. URN: urn:nbn:de:0114-fqs0901342

COSO MODELİ: İÇ KONTROL YAPISI - COSO MODEL: INTERNAL CONTROL STRUCTURE

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Hasan TÜREDİ

2014-08-01

Full Text Available Özetİktisadi ve teknolojik gelişmeler; zaman içinde çok sayıda faaliyetin çok sayıda kişi ve uzun süreçlerleyürütüldüğü, hiyerarşik örgütsel düzenlerin sürekli geliştiği, karmaşık işletme yapılarının ortaya çıkmasınaneden olmuştur. Bunun sonucunda işletmelerin faaliyetleri basit kontrol yöntemleriyle izlenemeyecek halegelmiştir. Amerika’da beş bağımsız meslek kuruluşundan oluşan COSO (The Committe of SponsoringOrganizations, iç kontrolün işletmelerde standartlaşan bir yapı hale gelmesinde öncülük etmiştir. COSOiç kontrol modeli; iç kontrol ortamı, risk değerlendirmesi, kontrol faaliyetleri, bilgi ve iletişim ile izlemefaaliyetlerinden oluşan; işletme faaliyetlerinin etkinliği ve verimliliği, mali raporların güvenilirliği veyürürlükteki kanun ve düzenlemelerle uyum amaçları etrafında şekillenmiş çok boyutlu bir yapıdır.İç kontrol yapısının başlıca hedefleri; faaliyetlerin etkinlik ve verimliliği, karlılık hedefine ulaşmak vevarlıkların korunması, kamuya açıklanan mali tablolar, geçici ve özet mali raporları da dâhil olmak üzerehazırlanan tüm mali tabloların güvenilirliğinin sağlanması ve tabi olunan kanun ve düzenlemelerle uyumunsağlanmasıdır. Bu çalışmada; COSO’nun iç kontrol yapısına ilişkin geliştirdiği model ve bu modelin beşbileşeni olan kontrol ortamı, risk değerlendirmesi, kontrol faaliyetleri, bilgi ve iletişim ile izleme faaliyetleriaracılığı ile bu bileşenlerin hem işletme hedefleri hem de işletme yapısı içindeki etkileşimi açıklanmayaçalışılmıştır.AbstractDevelopments in economy and technology have caused enterprises to have sophisticated structuresaffected by developing hierarchical structuring along with the significant number of activities performed via significant number of process and individuals. COSO (The Committee of Sponsoring Organizationshas established a common internal control

COSO MODELİ: İÇ KONTROL YAPISI - COSO MODEL: INTERNAL CONTROL STRUCTURE

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Hasan TÜREDİ

2014-07-01

Full Text Available Özetİktisadi ve teknolojik gelişmeler; zaman içinde çok sayıda faaliyetin çok sayıda kişi ve uzun süreçlerleyürütüldüğü, hiyerarşik örgütsel düzenlerin sürekli geliştiği, karmaşık işletme yapılarının ortaya çıkmasınaneden olmuştur. Bunun sonucunda işletmelerin faaliyetleri basit kontrol yöntemleriyle izlenemeyecek halegelmiştir. Amerika’da beş bağımsız meslek kuruluşundan oluşan COSO (The Committe of SponsoringOrganizations, iç kontrolün işletmelerde standartlaşan bir yapı hale gelmesinde öncülük etmiştir. COSOiç kontrol modeli; iç kontrol ortamı, risk değerlendirmesi, kontrol faaliyetleri, bilgi ve iletişim ile izlemefaaliyetlerinden oluşan; işletme faaliyetlerinin etkinliği ve verimliliği, mali raporların güvenilirliği veyürürlükteki kanun ve düzenlemelerle uyum amaçları etrafında şekillenmiş çok boyutlu bir yapıdır.İç kontrol yapısının başlıca hedefleri; faaliyetlerin etkinlik ve verimliliği, karlılık hedefine ulaşmak vevarlıkların korunması, kamuya açıklanan mali tablolar, geçici ve özet mali raporları da dâhil olmak üzerehazırlanan tüm mali tabloların güvenilirliğinin sağlanması ve tabi olunan kanun ve düzenlemelerle uyumunsağlanmasıdır. Bu çalışmada; COSO’nun iç kontrol yapısına ilişkin geliştirdiği model ve bu modelin beşbileşeni olan kontrol ortamı, risk değerlendirmesi, kontrol faaliyetleri, bilgi ve iletişim ile izleme faaliyetleriaracılığı ile bu bileşenlerin hem işletme hedefleri hem de işletme yapısı içindeki etkileşimi açıklanmayaçalışılmıştır.AbstractDevelopments in economy and technology have caused enterprises to have sophisticated structuresaffected by developing hierarchical structuring along with the significant number of activities performed via significant number of process and individuals. COSO (The Committee of Sponsoring Organizationshas established a common internal control

Intervention mapping protocol for developing a theory-based diabetes self-management education program.

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Song, Misoon; Choi, Suyoung; Kim, Se-An; Seo, Kyoungsan; Lee, Soo Jin

2015-01-01

Development of behavior theory-based health promotion programs is encouraged with the paradigm shift from contents to behavior outcomes. This article describes the development process of the diabetes self-management program for older Koreans (DSME-OK) using intervention mapping (IM) protocol. The IM protocol includes needs assessment, defining goals and objectives, identifying theory and determinants, developing a matrix to form change objectives, selecting strategies and methods, structuring the program, and planning for evaluation and pilot testing. The DSME-OK adopted seven behavior objectives developed by the American Association of Diabetes Educators as behavioral outcomes. The program applied an information-motivation-behavioral skills model, and interventions were targeted to 3 determinants to change health behaviors. Specific methods were selected to achieve each objective guided by IM protocol. As the final step, program evaluation was planned including a pilot test. The DSME-OK was structured as the 3 determinants of the IMB model were intervened to achieve behavior objectives in each session. The program has 12 weekly 90-min sessions tailored for older adults. Using the IM protocol in developing a theory-based self-management program was beneficial in terms of providing a systematic guide to developing theory-based and behavior outcome-focused health education programs.

Adhesion of Pseudomonas aeruginosa to orthokeratology and alignment lenses.

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Choo, Jennifer D; Holden, Brien A; Papas, Eric B; Willcox, Mark D P

2009-02-01

To determine whether contact lenses designed for orthokeratology (OK) are colonized by greater numbers of bacteria compared with standard (alignment fitted) design rigid gas permeable lenses before and after lens wear. Eighteen 1-year-old cats were randomly fitted with an OK lens in one eye and an alignment fitted (AF) lens in the other eye. Both lenses were made in the same diameter and central thickness and of the same material. Two separate wearing periods of 2 weeks and 6 weeks were used. After each wearing period, lenses were soaked in Pseudomonas aeruginosa (6294 or 6206) for 10 min. The lenses were then reinserted onto their respective corneas for a wearing period of 16 hours after which lenses were collected and remaining adhered bacteria quantified. Unworn control lenses were also soaked and bacteria enumerated for comparison. There were no significant differences in the number of bacteria adherent to unworn AF and OK lenses. Analysis of lenses after wear showed OK lenses retained significantly higher numbers of viable bacteria than AF lenses in all studies. OK lenses retain more bacteria than AF rigid gas permeable lenses after bacteria-loaded overnight lens wear. This may increase the risk for an infection in OK patients should suitable conditions be present. Specific education on the cleaning of OK lenses is essential.

Aaron V. Cicourel: I Am NOT Opposed to Quantification or Formalization or Modeling, but I Do Not Want to Pursue Quantitative Methods That Are Not Commensurate With the Research Phenomena Addressed

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Andreas Witzel

2004-09-01

Full Text Available In this interview, which was conducted mainly by e-mail, we trace the evolution of Aaron V. CICOUREL's thinking and career. In Part 1 we begin with his undergraduate education, then as a doctoral student, as an assistant professor, and his experiences with field research. Part 2 con­tains his critical reflections on the ecological val­idity problem which underlie self-contained inter­views and surveys that lack ethnographic data. In Part 3 he shows that it is necessary—and this is his specific contribution to the qualitative approach—to reflect on respondents' daily life experiences and understanding of fixed-choice or open-ended questions. Many strategies for valid interviews are also discussed in this part. Part 4 contains CICOUREL's reflections on the broad field of qualitative research and his own current research on daily life decision-making, routine information and communication processing, or activating memo­ry. Different methods for analyzing natural settings are proposed. In the Part 5 general devel­op­ments in qualitative research—challenges, ob­sta­cles and solutions—are pointed out. In Part 6 CICOUREL describes national differences of research cultures in the United States, Europe, and Latin America. URN: urn:nbn:de:0114-fqs0403412

The Mathematics of Mixing Things Up

Science.gov (United States)

Diaconis, Persi

2011-08-01

How long should a Markov chain Monte Carlo algorithm be run? Using examples from statistical physics (Ehrenfest urn, Ising model, hard discs) as well as card shuffling, this tutorial paper gives an overview of a body of mathematical results that can give useful answers to practitioners (viz: seven shuffles suffice for practical purposes). It points to new techniques (path coupling, geometric inequalities, and Harris recurrence). The discovery of phase transitions in mixing times (the cutoff phenomenon) is emphasized.

Unveiling the participation of avian kinin ornithokinin and its receptors in the chicken inflammatory response.

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Guabiraba, Rodrigo; Garrido, Damien; Bailleul, Geoffrey; Trotereau, Angélina; Pinaud, Mélanie; Lalmanach, Anne-Christine; Chanteloup, Nathalie K; Schouler, Catherine

2017-06-01

Vasoactive peptides are key early mediators of inflammation released through activation of different enzymatic systems. The mammalian kinin-kallikrein (K-KLK) system produces bradykinin (BK) through proteolytic cleavage of a kininogen precursor by enzymes named kallikreins. BK acts through specific ubiquitous G-protein coupled receptors (B1R and B2R) to participate in physiological processes and inflammatory responses, such as activation of mononuclear phagocytes. In chickens, the BK-like nonapeptide ornithokinin (OK) has been shown to promote intracellular calcium increase in embryonic fibroblasts and to be vasodilatory in vivo. Also, one of its receptors (B2R) was already cloned. However, the participation of chicken K-KLK system components in the inflammatory response remains unknown and was therefore investigated. We first showed that B1R, B2R and kininogen 1 (KNG1) are expressed in unstimulated chicken tissues and macrophages. We next showed that chicken B1R and B2R are expressed at transcript and protein levels in chicken macrophages and are upregulated by E. coli LPS or avian pathogenic E. coli (APEC) infection. Interestingly, exogenous OK induced internalization and degradation of OK receptors protein, notably B2R. Also, OK induced intracellular calcium increase and potentiated zymosan-induced ROS production and Dextran-FITC endocytosis by chicken macrophages. Exogenous OK itself did not promote APEC killing and had no pro-inflammatory effect. However, when combined with LPS or APEC, OK upregulated cytokine/chemokine gene expression and NO production by chicken macrophages. This effect was not blocked by canonical non-peptide B1R or B2R receptor antagonists but was GPCR- and PI3K/Akt-dependent. In vivo, pulmonary colibacillosis led to upregulation of OK receptors expression in chicken lungs and liver. Also, colibacillosis led to significant upregulation of OK precursor KNG1 expression in liver and in cultured hepatocytes (LMH). We therefore provide hitherto

Participant Action Research in Political, Psychological, and Gender Studies

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Olga Lucia Obando-Salazar

2006-09-01

Full Text Available Qualitative methodology is used in social and intervention research because it facilitates a deeper analysis of causal factors and development of alternative solutions to social problems. Based on the findings of three studies in the field of political and gender psychology, this article focuses on Participant Action Research (PAR as a useful qualitative approach to deal with social phenomena, such as racism, violence against women, and the problem of children and youth who have been dislocated as the result of armed conflict and sheltered by the Colombian government's program for persons relocated to civil society. This article is composed of three parts. The first part offers historical and theoretical background to the Action Research (AR paradigm, its validation criteria and their meaning for the development of the Latin American rendering of Participant Action Research (PAR. The second part synthesizes trends in the AR approach in the United States and Germany, discusses feminist research and compares these to trends in PAR in Latin America. The third part is a description of Participant Action Research as an intervention method, including features, models, goals, and concepts. URN: urn:nbn:de:0114-fqs060438

Conference Report: "Health Policy and Programs Evaluative Research for Social Change". An Ibero-American Symposium

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Francisco Mercado-Martínez

2008-05-01

Full Text Available This is a report of the "Health Policy and Programs Evaluative Research for Social Change" Ibero-American Symposium held in Guadalajara, Mexico November 1-3, 2006. Attendees represented eight countries, and were associated with NGO's and academic and health services organizations. The most important themes included in the debates were the meaning of qualitative and evaluative health research for social change, the challenges of teaching for change, ethical challenges, and possibilities for making the findings of qualitative research available to different groups or stakeholders (users, policy makers, professionals, and the population as a whole. URN: urn:nbn:de:0114-fqs0802194

Review Essay: Auto/Ethnography and Tinsel Town: Nathaniel Kohn's Pursuing Hollywood and How it Relates to My Own Experiences Chasing the Dream of Creating Culture Through Cinema

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Michael Hemmingson

2008-07-01

Full Text Available In Nathaniel KOHN's Pursuing Hollywood, auto/ethnography and interpretive interaction are discussed alongside postmodern sign theory and the machinations of making films in the Hollywood system. Interwoven into this review-essay of KOHN's book are auto/ethnographical elements of the reviewer's personal experiences making an independent film and doing business in what the reviewer refers to as "La La Land." While KOHN's book is meant to be an insider's gaze onto a world few know first-hand, the reviewer has had similar experiences and reads the book as an identifying text and a launch point for his own experiential accounts. URN: urn:nbn:de:0114-fqs080399

Review: Hanna Meißner (2010. Jenseits des autonomen Subjekts. Zur gesellschaftlichen Konstitution von Handlungsfähigkeit [Beyond Human Autonomy. The Social Constitution of Agency Based on Butler, Foucault and Marx

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Lisa Pfahl

2012-03-01

Full Text Available Based on the theories of Judith BUTLER, Michel FOUCAULT, and Karl MARX, Hanna MEIßNER analyzes the historical, legal and social conditions of the emergence of subjectivity. She establishes a critical understanding of human autonomy and the potential of practices of resistance in the context of existing conditions. Both MEIßNER's analytical structure and her precise argumentation are convincing. By highlighting the relationship of individual self-determination and collective welfare, this study provides helpful links to different theoretical approaches, particularly to the emerging disciplines of disability studies and diversity studies in Germany. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1202181

Interpretative Visual Analysis. Developments, State of the Art and Pending Problems

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Bernt Schnettler

2008-09-01

Full Text Available he article offers a brief resume of recent developments in the field of interpretative visual analysis with emphasis on the German speaking area and the sociological discipline. It lays a special focus on hermeneutical and genre analysis and on research with audiovisual data. Far from constituting an already closed field, the authors stress the fact that methodological advances in qualitative research based in visual data still face a number of pending quests. This encompasses sequentiality, complexity and naturalness of videographic data, and extends to the respective methodological challenges for transcription, analysis and presentation of results. URN: urn:nbn:de:0114-fqs0803314

But What Is Interesting Is the Story of Why and How Migration Happened

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Carla De Tona

2006-05-01

Full Text Available Qualitative methodologies in migration studies are bringing new emphasis on the old question of the role and positionality of the researcher. The researcher with an experience of migration and as a member of a minority community is positioned in a qualitative research process in a particularly interesting and revealing way. We ask Ronit LENTIN and Hassan BOUSETTA to consider the implications of such a positionality. The questions raised are focusing on their experiences as migrant/minority researchers, with particular emphasis placed on gender and on the potential of a reflexive engagement with positionality to disrupt asymmetrical power relations in the field. URN: urn:nbn:de:0114-fqs0603139

Narrating Oneself: Reflections on the use of Solicited Diaries with Diary Interviews

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Charlotte Kenten

2010-05-01

Full Text Available In using the solicited diaries to access the everyday ways in which self-identified lesbians and gay men are made aware of their sexuality, this paper considers the role of solicited diaries combined with diary interviews. Furthermore it draws on empirical evidence to argue that a diary interview provides a richer, deeper and contextual understanding of the documented experiences. The paper reflects on the participants' experiences of keeping the solicited diary, the narratives produced through the solicited diaries and heterosexism as one the main themes to emerge from the solicited diaries and diary interview analysis. URN: urn:nbn:de:0114-fqs1002160

A Call for Critical Perspectives in Qualitative Research

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Rainer Winter

2010-11-01

Full Text Available The formation of critical poststructuralism in the United States has fundamentally transformed qualitative research. The crisis of representation first discussed in anthropology has had the effect of rethinking the foundations of qualitative research by putting ethical questions on the agenda and stimulating a search for new forms of validity. Against this backdrop, this study will analyze different methods and research strategies in critical qualitative inquiry, such as interpretive interactionism, autoethnography, and performance ethnography. The call to action inherent in these strategies and further contributions to cultural and social change will be discussed. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs110171

Review: Irena Medjedović & Andreas Witzel (2010. Wiederverwendung qualitativer Daten. Archivierung und Sekundärnutzung qualitativer Interviewtranskripte [Reusing Qualitative Data. Archiving and Secondary Use of Qualitative Interview Transcripts

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Dina El-Najjar

2011-03-01

Full Text Available Irena MEDJEDOVIĆ and Andreas WITZEL's work offers an insight into the topic of secondary analysis and research. The composition of the book is well-conceived, and chapter by chapter the authors examine the various facets of secondary analysis. The book covers key issues on the topic of secondary analysis, referring not only to existing literature but also using examples that foster a better understanding of this research strategy. They succeed in stimulating interest in this topic, as well as illustrating the effectiveness of this research method and reducing skepticism and doubt regarding secondary analysis. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1102205

Review: Katrin Döveling (2005. Emotionen – Medien – Gemeinschaft. Eine kommunikationssoziologische Analyse [Emotions—Media—Society. A Communication-Sociological Analysis

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Sascha Demarmels

2007-09-01

Full Text Available The goal of this book is it to take a first step in the interdisciplinary elaboration of the theory of emotions in the media. Theories of media and communication sciences are linked to theories from sociology, and pre-existing instruments are further developed. A case study involving group-specific reporting is used to test the resulting theory in practice. Methodologically, qualitative content analysis is used successfully, and both theory and practical implementation are done well. But the book shows also the boundaries of the interdisciplinary working process, present whenever the boundaries of individual knowledge are reached. URN: urn:nbn:de:0114-fqs0703286

Chemical pleurodesis for prolonged postoperative air leak in primary spontaneous pneumothorax.

Science.gov (United States)

How, Cheng-Hung; Tsai, Tung-Ming; Kuo, Shuenn-Wen; Huang, Pei-Ming; Hsu, Hsao-Hsun; Lee, Jang-Ming; Chen, Jin-Shing; Lai, Hong-Shiee

2014-05-01

Prolonged air leak is the most common complication after thoracoscopic operation for primary spontaneous pneumothorax (PSP), and the role of chemical pleurodesis in treating air leaks remains unclear. This study evaluated the safety and efficacy of chemical pleurodesis with a comparison between minocycline and OK-432. Between 1994 and 2011, 1083 PSP patients were treated by thoracoscopic operation. After the operation, patients with persistent air leak for 3 days or more were managed by minocycline or OK-432 pleurodesis. The demographic and outcome data for these patients were collected by retrospective chart review. Seventy-nine patients (7.3%) with prolonged air leak after thoracoscopy underwent minocycline pleurodesis (60 patients) or OK-432 pleurodesis (19 patients) as the primary treatment. The primary success rate was 63% (38/60) for minocycline pleurodesis and 95% (18/19) for OK-432 pleurodesis (p = 0.009). Postpleurodesis pain was common and comparable between the two groups. No major complications were noted after a total of 121 treatments. Patients undergoing primary OK-432 pleurodesis had shorter durations of postpleurodesis chest drainage (mean 8.5 vs. 2.3 days; p < 0.001) and postoperative hospital stay (mean 11.9 vs. 6.8 days; p < 0.001) than those undergoing primary minocycline pleurodesis. After a median follow-up of 16 months, recurrence was noted in one patient in the OK-432 group and none in the minocycline group. Long-term pulmonary function in the two groups was comparable. Chemical pleurodesis using OK-432 or minocycline is safe and convenient for prolonged air leak after thoracoscopic treatment for PSP. Our experience suggested that OK-432 may be more effective than minocycline in reducing air leak. Copyright © 2013. Published by Elsevier B.V.

Factors related to axial length elongation and myopia progression in orthokeratology practice.

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Bingjie Wang

Full Text Available To investigate which baseline factors are predictive for axial length growth over an average period of 2.5 years in a group of children wearing orthokeratology (OK contact lenses.In this retrospective study, the clinical records of 249 new OK wearers between January 2012 and December 2013 from the contact lens clinic at the Eye and ENT Hospital of Fudan University were reviewed. The primary outcome measure was axial length change from baseline to the time of review (July-August 2015. Independent variables included baseline measures of age at initiation of OK wear, gender, refractive error (spherical equivalent, astigmatism, average keratometry, corneal toricity, central corneal thickness, white-to-white corneal diameter, pupil size, corneal topography eccentricity value (e-value, intraocular pressure (IOP and total time in follow-up (months total. The contributions of all independent variables on axial length change at the time of review were assessed using univariate and multivariable regression analyses.Univariate analyses of the right eyes of 249 OK patients showed that smaller increases in axial length were associated with older age at the onset of OK lens wear, greater baseline spherical equivalent myopic refractive error, less time in follow-up and a smaller e-value. Multivariable analyses of the significant right eye variables showed that the factors associated with smaller axial length growth were older age at the onset of OK lens wear (p<0.0001, greater baseline spherical equivalent myopic refractive error (p = 0.0046 and less time in follow-up (p<0.0001.The baseline factors demonstrating the greatest correlation with reduced axial length elongation during OK lens wear in myopic children included greater baseline spherical equivalent myopic refractive error and older age at the onset of OK lens wear.

Heritable genome editing with CRISPR/Cas9 in the silkworm, Bombyx mori.

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Wei Wei

Full Text Available We report the establishment of an efficient and heritable gene mutagenesis method in the silkworm Bombyx mori using modified type II clustered regularly interspaced short palindromic repeats (CRISPR with an associated protein (Cas9 system. Using four loci Bm-ok, BmKMO, BmTH, and Bmtan as candidates, we proved that genome alterations at specific sites could be induced by direct microinjection of specific guide RNA and Cas9-mRNA into silkworm embryos. Mutation frequencies of 16.7-35.0% were observed in the injected generation, and DNA fragments deletions were also noted. Bm-ok mosaic mutants were used to test for mutant heritability due to the easily determined translucent epidermal phenotype of Bm-ok-disrupted cells. Two crossing strategies were used. In the first, injected Bm-ok moths were crossed with wild-type moths, and a 28.6% frequency of germline mutation transmission was observed. In the second strategy, two Bm-ok mosaic mutant moths were crossed with each other, and 93.6% of the offsprings appeared mutations in both alleles of Bm-ok gene (compound heterozygous. In summary, the CRISPR/Cas9 system can act as a highly specific and heritable gene-editing tool in Bombyx mori.

Cross-cultural adaptation and validation of the persian version of the oxford knee score in patients with knee osteoarthritis.

Science.gov (United States)

Ebrahimzadeh, Mohammad Hosein; Makhmalbaf, Hadi; Birjandinejad, Ali; Soltani-Moghaddas, Seyed Hosein

2014-11-01

The Oxford Knee Score (OKS) is a short patient-reported outcome instrument that measures pain and physical activity related to knee osteoarthritis. The purpose of this study is to evaluate, construct validity and consistent reliability of the Persian version of the OKS. The case series consisted of 80 patients who were clinically diagnosed with having knee osteoarthritis. All patients were requested to fill-in the Persian OKS and Short-Form 36 Health Survey (SF-36). Correlation analysis between the Persian versions of these two instruments was then carried out. The scores of the Persian SF-36 were used to evaluate convergent and divergent validity of the 12-item Persian OKS. From a total of 80 patients, 63 were female (79%) and the remaining 17 were male (21%) with a mean age of 52.2 years. In the present study, high Cronbach's alpha of 0.95 confirms excellent internal consistency of the Persian OKS scale similar to previous investigations. The results confirm that the Persian version of this instrument is valid and reliable, similar to its English index and its subsequent translations in different languages. The Persian OKS is a reliable instrument to evaluate knee function in patients with knee osteoarthritis and is a useful tool for outcome measurement in clinical research.

Some herding, record keeping and treatment methods used in Alaskan reindeer herds

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Robert A. Dieterich

1986-06-01

Full Text Available Approximately 20000 reindeer (Rangifer tarandus in Alaska are gathered once or twice yearly to facilitate identification, serologic sampling, treatment and antler removal. Various air and land craft are used to bring the animals into a corral system from which they can be herded into a padded, pneumatically operated, squeeze apparatus. Ear tags are applied or read if already in place and ears are notched. A portable, computerized rapid data retrieval system is used to record reproductive success, vaccination and treatment status and other miscellaneous information. Ivermectin is being administered in the early winter months to treat reindeer in many herds for warbles, nasal bots and internal parasites. A killed, homologous Brucella suis type 4 vaccine is being used in two large (3500 herds. Efforts are being made to incorporate other innovative methods to improve herding and corralling methods.

Aspectos Socioculturales de Migrantes Mexicanos a Estados Unidos de América. Casos de Estudio: San Isidro de Gamboa y Corral de Piedra, en el Municipio de Apaseo El Alto, Guanajuato, México

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María del Pilar Longar Blanco

2011-06-01

Full Text Available A lo largo de la investigación, se usó la información referente al tema de la migración de mexicanos a los Estados Unidos de América E.U.A. (United States of America, USA, en el comportamiento sociocultural del migrante mexicano en Estados Unidos E. U. (United States U. S. y su retorno al lugar de origen. Se utilizó una metodología de tipo cuantitativo y cualitativo para interpretar los resultados de la Encuesta sobre Migración en la Frontera Norte de México (EMIF tanto a nivel nacional como local; específicamente para el estado de Guanajuato, se obtuvo el diagnóstico relativo a datos estadísticos del flujo migratorio de mexicanos a Estados Unidos; para la obtención de información sociodemográfica, económica, política y cultural de los individuos que se encuentran desplazándose y son interrogados en un punto localizable en el espacio y tiempo. Se llevó a cabo el análisis de los aspectos socioculturales de los migrantes temporales, a través del diseño y aplicación de un cuestionario a este grupo, en las comunidades seleccionadas como casos de estudio: San Isidro de Gamboa y Corral de Piedra, en el Municipio de Apaseo el Alto, Guanajuato; los resultados permiten conocer el comportamiento sociocultural del migrante, respecto a los tipos de organizaciones sociales prevalecientes, programas de desarrollo comunitario, prácticas políticas, sistema de cargos, costumbres de vestimenta, y formas de construcción de casas-habitación, entre otros; al retornar al lugar de origen, producto de su migración temporal a los Estados Unidos de América. Paralelamente, se observó una realidad en el campo mexicano para el período 2000-2006. Es donde prevalece la mayor crisis histórica en el medio rural y que tiene como constantes la pobreza y exclusión social. Con el incremento de migración permanente, jóvenes en su mayoría buscan la sobrevivencia.

Calculation Methods for Wallenius’ Noncentral Hypergeometric Distribution

DEFF Research Database (Denmark)

Fog, Agner

2008-01-01

Two different probability distributions are both known in the literature as "the" noncentral hypergeometric distribution. Wallenius' noncentral hypergeometric distribution can be described by an urn model without replacement with bias. Fisher's noncentral hypergeometric distribution...... is the conditional distribution of independent binomial variates given their sum. No reliable calculation method for Wallenius' noncentral hypergeometric distribution has hitherto been described in the literature. Several new methods for calculating probabilities from Wallenius' noncentral hypergeometric...... distribution are derived. Range of applicability, numerical problems, and efficiency are discussed for each method. Approximations to the mean and variance are also discussed. This distribution has important applications in models of biased sampling and in models of evolutionary systems....

Optokinetic Stimulation Modulates Neglect for the Number Space: Evidence from Mental Number Interval Bisection

Science.gov (United States)

Priftis, Konstantinos; Pitteri, Marco; Meneghello, Francesca; Umiltà, Carlo; Zorzi, Marco

2012-01-01

Behavioral, neuropsychological, and neuroimaging data support the idea that numbers are represented along a mental number line (MNL), an analogical, visuospatial representation of number magnitude. The MNL is left-to-right oriented in Western cultures, with small numbers on the left and larger numbers on the right. Left neglect patients are impaired in the mental bisection of numerical intervals, with a bias toward larger numbers that are relatively to the right on the MNL. In the present study we investigated the effects of optokinetic stimulation (OKS) – a technique inducing visuospatial attention shifts by means of activation of the optokinetic nystagmus – on number interval bisection. One patient with left neglect following right-hemisphere stroke (BG) and four control patients with right-hemisphere damage, but without neglect, performed the number interval bisection task in three conditions of OKS: static, leftward, and rightward. In the static condition, BG misbisected to the right of the true midpoint. BG misbisected to the left following leftward OKS, and again to the right of the midpoint following rightward OKS. Moreover, the variability of BG’s performance was smaller following both leftward and rightward OKS, suggesting that the attentional bias induced by OKS reduced the “indifference zone” that is thought to underlie the length effect reported in bisection tasks. We argue that shifts of visuospatial attention, induced by OKS, may affect number interval bisection, thereby revealing an interaction between the processing of the perceptual space and the processing of the number space. PMID:22363280

Modelling Supplementation Strategies for Beef Steer Rearing and Fattening Systems in Southern Chile Modelación de Estrategias de Suplementación en la Recría y Engorda de Novillos en el Sur de Chile

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Paula Toro

2009-06-01

Full Text Available A mathematical model was developed to analyze beef production systems in Southern Chile. The study considered the identification of the main components of systems under different beef steer management strategies, using pasture with or without supplementation and back grounding cattle on pasture followed by a winter period of confined feeding with pasture silage and concentrates. Validation of model outputs using 200 kg LW Hereford steers against real experimental data showed no significant differences (P ≥ 0.01 between simulated and observed final weights. In order to analyze the interaction between the stocking rate (SR and supplementation, three SR of 2, 2.5 and 3 steers ha-1 with and without pasture silage supplementation at the rate of 5 kg DMd-1 steer-1 for the length of the entire period were simulated. Means were compared by the least significant difference (LSD, P ≤ 0.05. Significant differences were found in terms of final weights, which decreased with increasing SR regardless of the supplementation level, although silage supplementation tended to reduce differences between SR. A second set of simulation runs was carried out to simulate on-farm finishing of the steers through a final phase of confined feeding based on a ration of silage and concentrates. Final weights differed between SR and systems and results showed that the optimum corresponded to 2.5 steers ha-1, since at this SR the largest income corresponded to the smallest mean cost. It is concluded that a stocking rate of 2.5 steers ha-1 is feasible if winter supplementation is available, independently of a finishing period in feedlot.Un modelo matemático fue desarrollado para analizar sistemas de producción de carne bovina en el Sur de Chile. El estudio consideró la identificación de los componentes en diferentes estrategias usadas en novillos de carne, usando praderas con y sin suplementación y la recría seguida por una engorda a corral en invierno con ensilaje de

78 FR 25293 - Notice of Intent To Change HUD-Wide the Operating Model of the Office of Multifamily Housing

Science.gov (United States)

2013-04-30

..., Indianapolis IN, Minneapolis MN, Cleveland OH, Milwaukee WI, Little Rock AK, New Orleans LA, Albuquerque NM... workforce. Important progress has been made to date, including improving productivity, reducing loan cycle..., Cleveland OH, Milwaukee WI, Little Rock AK, New Orleans LA, Albuquerque NM, Oklahoma City OK, Houston TX...

Reduced Bearing Excursion After Mobile-Bearing Unicompartmental Knee Arthroplasty is Associated With Poor Functional Outcomes.

Science.gov (United States)

Wahal, Naman; Gaba, Sahil; Malhotra, Rajesh; Kumar, Vijay; Pegg, Elise C; Pandit, Hemant

2018-02-01

A small proportion of patients with mobile unicompartmental knee arthroplasty (UKA) report poor functional outcomes in spite of optimal component alignment on postoperative radiographs. The purpose of this study is to assess whether there is a correlation between functional outcome and knee kinematics. From a cohort of consecutive cases of 150 Oxford medial UKA, patients with fair/poor functional outcome at 1-year postsurgery (Oxford Knee Score [OKS] bearing position with knee flexion angle. Mean OKS in the fair/poor group was 29.9 and the mean OKS in the good/excellent group was 41.1. The tibial slope, time taken to complete the exercises, and patellar tendon angle trend over the flexion range were similar in both the groups; however, bearing position and the extent of bearing excursion differed significantly. The total bearing excursion in the OKS bearing was positioned 1.7 mm more posterior on the tibia in the OKS bearing excursion and positioning, are associated with worse functional outcomes after mobile UKA. Copyright © 2017 Elsevier Inc. All rights reserved.

Comparison of the bioavailability of elemental waste laden soils using in vivo and in vitro analytical methodology and refinement of exposure/dose model. 1997 annual progress report

International Nuclear Information System (INIS)

Gailo, M.; Georgopoulos, P.; Lioy, P.J.; Roy, A.

1997-01-01

'The bioavailability study has made significant progress in developing in vitro methodology, and the authors have completed the time course in vivo studies. The in vitro studies have been conducted to establish the major digestive variables of concern and the values to be used in application of both the saliva/gastric juice and intestinal fluid components of a synthetic digestive extraction. In vitro and in vivo experiments have been conducted on the 575 urn particle fraction of a soil sample collected in a Jersey City State Park. Five Jersey City soil samples were first characterized for physical and chemical characteristics. Based upon the composition of the five soils, one was selected for use in the first series of experiments. The second set of in vivo studies are to be conducted on a standard NIST Montana soil. It has already been examined for bioaccessibility and availability with the in vitro methodology. A sample has been collected in Bayonne to obtain an urban background soil. Surficial soil samples have been acquired from the Savannah River Site of the DOE. These are not radioactive but are contaminated with heavy metals, e.g. arsenic, and are being analyzed by both the in vivo and in vitro methodology. During this past summer a second set of soil samples were collected at Savannah River Site. These contain levels of both heavy metals and radionuclides. Recently, a special extraction laboratory has been constructed at EOHSI, with resources made available from the organization. It will handle the extraction and measurement of the radio activity of the soil, and extracts obtained by the in vivo techniques. It is anticipated that the SRS samples collected this summer will be available for analysis in both the in vivo and in vitro systems this fall. The initial characterization will be for soil, physical and chemical content, and microbial characteristics. The samples will be analyzed for the 5 75 urn particle size fraction, and the total mass 5 250 urn in

Review: Thomas S. Eberle, Sabine Hoidn & Katarina Sikavica (Eds. (2007. Fokus Organisation. Sozialwissenschaftliche Perspektiven und Analysen [Focus Organization: Social Scientific Perspectives and Analyses

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Jo Reichertz

2008-11-01

Full Text Available This transdisciplinary anthology was published on the occasion of the 65th birthday of Emil WALTER-BUSCH, an organization scientist from St. Gallen, Switzerland. Alongside discussions of current theories about the character of organizations, the collection introduces and evaluates international management research as well as approaches to organizational change. All the articles are embedded in a reflexive approach to the production of social-scientific knowledge. This anthology, as interesting for organization researchers as for sociologists of knowledge and science, is particularly successful in not only taking up and developing the thoughts of Emil WALTER-BUSCH but also in capturing the spirit of his scientific work. URN: urn:nbn:de:0114-fqs0901219

Review: Helga Kotthoff (Ed. (2002. Kultur(en im Gespräch [Culture(s in Conversation

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Matthias Otten

2003-09-01

Full Text Available Much of the theoretical and empirical research on intercultural communication in Germany emerges at the disciplinary edges of Linguistics, Sociology, Anthropology, Psychology or Educational Studies. The book "Kultur(en im Gespräch"—translated roughly as Culture(s in Conversation—edited by Helga KOTTHOFF, covers a wide range of theoretical and methodical approaches to the analysis of intercultural conversation and discourse. Most of the contributions refer to concepts of Socio-Linguistics and Linguistic Anthropology. The focus on the reflection of applying qualitative research methods used in the scope of intercultural conversation and discourse analysis let this book become a source of inspiration for the own research practice. URN: urn:nbn:de:0114-fqs030345

Review Essay: Faltering Forms Go to School. Analysis of the Subject in Connection With Andreas Reckwitz

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Johannes Twardella

2009-03-01

Full Text Available In his book "Subjectivity," Andreas RECKWITZ interprets the work of a series of structuralist and poststructuralist authors in relation to the analysis of subjectivity. In the following article I reconstruct this interpretation and attempt to critically analyze the empirical explanatory power of these authors. An excerpt from the school routine of a German class is used to show how these various "subject-theoretical analysis strategies" may lead to different, interesting, and insightful interpretations. It also becomes clear that the idea of subjectivity, and therefore of education and maturity, cannot be abandoned. Without this idea, the application of pedagogy would be cynical, and the ability to understand it impossible. URN: urn:nbn:de:0114-fqs090222

Editorial Note: The Internet as "Scholarly Review Resource". Further Considerations about E-Reviewing on the Occasion of the "Special Issue: FQS Reviews IV"

Directory of Open Access Journals (Sweden)

Günter Mey

2006-03-01

Full Text Available With the growth in use of the Internet and the convenience of electronic publishing in terms of speed and publication space, book reviews have come to receive additional recognition (compared to traditional print media. This contribution points out the lack of a system for online reviewing despite multiple online review-services that already exist. Moreover, the full potential of electronic documents, such as the use of hypertext, hybrids and links to additional information, are not maximized. In order to strengthen the scientific impact of book reviews the inherent characteristics of book reviews must be more precisely defined and quality control, for example through peer review, is put in place. URN: urn:nbn:de:0114-fqs0602429

Review: Wilfried Breyvogel (Ed. (2005. Einführung in Jugendkulturen. Veganismus und Tattoos [Introduction to Youth Cultures. Veganism and Tattoos

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Sebastian Schröer

2007-09-01

Full Text Available Wilfried BREYVOGEL's introductory textbook combines three individual texts. As well as an historic overview of diverse "youth cultures" there are two extensive contributions devoted to veganism (Thomas SCHWARZ and tattoos (Tobias LOBSTÄDT. BREYVOGEL's contribution is a literature-based study, whereas SCHWARZ and LOBSTÄDT present work based on original research. However, expectations of an introductory textbook are disappointed because the book does not contain a well-founded and "tight" theoretical derivation on the topic of "youth cultures," and the two choice of the two exemplary youth cultures makes little sense. Furthermore, the individual contributions show flaws in both content and format. URN: urn:nbn:de:0114-fqs0703279

Ethnographic Discourse Analysis and Social Science

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Felicitas Macgilchrist

2011-01-01

Full Text Available Drawing on the perspectives of ethnography and discourse analysis, this paper first gives an overview of the emerging body of research bringing together the epistemologies and the methods of these two perspectives. It then presents a novel analytical framework for computer-assisted ethnographic discourse analysis. The paper outlines how close analysis of discursive practices—in this case journalistic writing practices—can provide insights into struggles over meaning and hegemony in contemporary knowledge work. The case study explores the production of a financial news story about the supply of gas to French consumers, and the way the practices in question subtly write Russia as a threat. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1101183

Towards a Poststructuralist Perspective on the Making and the Power of Maps. A Response to Ball and Petsimeris

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Boris Michel

2010-08-01

Full Text Available This paper takes the recent article "Mapping Urban Social Divisions" by BALL and PETSIMERIS, published in FQS, as a starting point for discussing the role of maps for visualizing knowledge and as an object of research in the social sciences. The paper draws on the theoretical approach of "critical cartography" which changed the conception of maps and the practice of mapmaking since the early 1990s. Critical cartography is deeply informed by a poststructuralist critique of knowledge and truth. Maps, no longer conceptualized as graphical images of reality where the only concern is the quality of the data, are powerful actors in the social construction of reality. URN: urn:nbn:de:0114-fqs1003281

Review: Günter Mey & Katja Mruck (Eds. (2007. Grounded Theory Reader

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Adrian Schmidtke

2009-07-01

Full Text Available The volume was published to mark the 40th anniversary of the publication of "The Discovery of Grounded Theory." The first part describes the emergence and fundamental positions of grounded theory methodology (GTM in methodological and theoretical terms; the second part focuses on research practices. The "Grounded Theory Reader" is an excellent compilation that doesn’t claim to be a standard textbook for newcomers to GTM. Rather, it is a reflection of the state of the art in GTM and enables insights in complex research practices. A basic understanding of GTM is recommended in order to get the most from the book. URN: urn:nbn:de:0114-fqs0903286

Review: Annette N. Markham & Nancy K. Baym (Eds. (2009. Internet Inquiry: Conversations About Method

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Alp Biricik

2010-08-01

Full Text Available As suggested by the title, this edited collection of articles is aimed at creating a dialogue on crosscutting epistemological and methodological issues relating to qualitative internet study. The scope of the book is not to provide quick tips, but rather encourage the reader to seek new methods of conducting online research. The book is creatively structured into six parts, each one addressing a key question on methods. In addition to the two editors' contributions, 13 accomplished scholars from various disciplines intelligibly respond and share their own qualitative research experiences in online environments, providing a precise and valuable contribution to current debates in internet studies. URN: urn:nbn:de:0114-fqs100396

Conference Report: Project Journal of Discourse Research and the Prospects of Disciplinary, Interdisciplinary and Transdisciplinary Cooperation

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Nils Matzner

2014-07-01

Full Text Available A symposium was held to mark the first anniversary of Journal of Discourse Research (ZfD, at which the status of German discourse research was discussed. Since its inception, German-language discourse research has been characterized by connections, challenges and limitations of interdisciplinarity in terms of both practical research and methodology. In four lectures and two panel discussions, participants explored specific issues of interdisciplinarity. Taking into account the difficult process of institutionalization of discourse research in the 1990s, it can be determined that a diverse and highly productive research environment has been created that marks a specific style of interdisciplinary thinking. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs140390

Competence and Career. A Double Career Structure and Reduced Recognition in Aging Institutions

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Sylvia Kade

2008-01-01

Full Text Available The occupation is a relationship of appropriation, which is only realized in relationships of recognition between organization and work. The organization includes its members by a mutual exchange of benefits, which is referred to as a relationship of recognition. The basic rule of the mutuality of relationships of recognition is called into question in knowledge-based organizations of "aging institutions." The limited reciprocity of the "closed opportunity structure" is the result of an institutional reduplication of a career policy under the pressure of innovations. A response to this is a change of individual career strategies. The article focuses on the consequences for the development of careers and competencies. URN: urn:nbn:de:0114-fqs0801592

The Documentary Method in Intercultural Research Scenarios

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Henrike Evers

2009-01-01

Full Text Available The documentary method appears to be especially suitable for preventing possible ethnocentrisms in the interpretation of data in reconstructive research, as well as for precluding concessions with a statistic and normative cultural concept. As an illustration of this thesis, this article presents a study—undertaken at the Bremen University of Applied Sciences—in which the effects of an intercultural contact programme between international students and German families are analysed. Special emphasis is placed on the question of the students' emotional and cognitive changes, called educational processes ("Bildung" in the educational science. The theoretical and methodological background of the study and exemplary results are presented. URN: urn:nbn:de:0114-fqs0901478

Cross-Cultural Adaptation and Validation of the Persian Version of the Oxford Knee Score in Patients with Knee Osteoarthritis

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Mohammad Hosein Ebrahimzadeh

2014-11-01

Full Text Available Background: The Oxford Knee Score (OKS is a short patient-reported outcome instrument that measures pain and physical activity related to knee osteoarthritis. The purpose of this study is to evaluate, construct validity and consistent reliability of the Persian version of the OKS. Methods: The case series consisted of 80 patients who were clinically diagnosed with having knee osteoarthritis. All patients were requested to fill-in the Persian OKS and Short-Form 36 Health Survey (SF-36. Correlation analysis between the Persian versions of these two instruments was then carried out. The scores of the Persian SF-36 were used to evaluate convergent and divergent validity of the 12-item Persian OKS. Results: From a total of 80 patients, 63 were female (79% and the remaining 17 were male (21% with a mean age of 52.2 years. In the present study, high Cronbach’s alpha of 0.95 confirms excellent internal consistency of the Persian OKS scale similar to previous investigations. The results confirm that the Persian version of this instrument is valid and reliable, similar to its English index and its subsequent translations in different languages. Conclusion: The Persian OKS is a reliable instrument to evaluate knee function in patients with knee osteoarthritis and is a useful tool for outcome measurement in clinical research.

Bactérias do gênero Aeromonas em água de matadouro bovino Aeromonas bacteria in beef slaughtering water

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O.D. Rossi Jr

2000-10-01

Full Text Available Verificou-se a ocorrência de bactérias do gênero Aeromonas em amostras de água (abastecimento/residuária obtidas em matadouro bovino. Analisaram-se a água utilizada nas dependências internas, a água dos currais, utilizada na dessedentação, pré-higienização e tranqüilização dos animais e a água residuária da lavagem das carcaças. Das 30 amostras representativas de cada tipo, bactérias do gênero Aeromonas foram isoladas em 10 (33,3% amostras da água dos currais e em 10 (33,3% amostras da água residuária da lavagem de carcaças. Nenhuma das amostras da água tratada de abastecimento das instalações revelou-se positiva no isolamento. As espécies isoladas foram Aeromonas hydrophila em duas (2,2% e Aeromonas caviae em 19 (21,1% amostras. Uma cepa considerada atípica foi isolada da água dos currais. Os resultados evidenciaram que a água dos currais pode ser uma importante fonte de contaminação, principalmente para a pele, e através dela as Aeromonas sp. podem chegar à sala de matança.The aim of this work was to verify the occurrence of Aeromonas bacteria in samples of water (supply and residual collected at beef slaughterhouse. Water used at the internal facilities, water from corrals, drinking water, water for pre-hygiene and tranquilization of the animals and residual water from carcasses’ wash, were analyzed. From those 30 samples of each type, Aeromonas bacteria were isolated in 10 (33.3% samples of corral water and in 10 (33.3% samples of residual water from carcasses’ wash. None of the facilities treated water supply samples showed positive in isolation. The isolated species were Aeromonas hydrophila in two (2.2% and Aeromonas caviae in 19 (21.1% of the samples. One non-typical strain was isolated from corral water. The results demonstrated that corral water may be an important contamination source, mainly to the hide and, through it, Aeromonas sp. can reach the slaughter room.

Feed and manure use in low-N-input and high-N-input dairy cattle production systems

Science.gov (United States)

Powell, J. Mark

2014-11-01

In most parts of Sub-Saharan Africa fertilizers and feeds are costly, not readily available and used sparingly in agricultural production. In many parts of Western Europe, North America, and Oceania fertilizers and feeds are relatively inexpensive, readily available and used abundantly to maximize profitable agricultural production. A case study, dairy systems approach was used to illustrate how differences in feed and manure management in a low-N-input dairy cattle system (Niger, West Africa) and a high-N-input dairy production system (Wisconsin, USA) impact agricultural production and environmental N loss. In Niger, an additional daily feed N intake of 114 g per dairy animal unit (AU, 1000 kg live weight) could increase annual milk production from 560 to 1320 kg AU-1, and the additional manure N could greatly increase millet production. In Wisconsin, reductions in daily feed N intake of 100 g AU-1 would not greatly impact milk production but decrease urinary N excretion by 25% and ammonia and nitrous oxide emissions from manure by 18% to 30%. In Niger, compared to the practice of housing livestock and applying dung only onto fields, corralling cattle or sheep on cropland (to capture urinary N) increased millet yields by 25% to 95%. The additional millet grain due to dung applications or corralling would satisfy the annual food grain requirements of 2-5 persons; the additional forage would provide 120-300 more days of feed for a typical head of cattle; and 850 to 1600 kg ha-1 more biomass would be available for soil conservation. In Wisconsin, compared to application of barn manure only, corralling heifers in fields increased forage production by only 8% to 11%. The application of barn manure or corralling increased forage production by 20% to 70%. This additional forage would provide 350-580 more days of feed for a typical dairy heifer. Study results demonstrate how different approaches to feed and manure management in low-N-input and high-N-input dairy cattle

Pinturas del Corral de Morcilla (Las Batuecas

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Julián BÉCARES PÉREZ

2009-10-01

Full Text Available Durante una de las frecuentes visitas que el Departamento de Prehistoria y Arqueología de Salamanca realiza a Las Batuecas tuvo lugar, en noviembre de 1973, el descubrimiento de un nuevo abrigo con pinturas por el Dr. Jordá, quien me brindó su publicación ayudándome en los trabajos de calco y estudio, por lo que le estoy muy agradecido.

Alkylation of 2,6-di-tert-butylphenol with methyl acrylate catalyzed by potassium-2,6-di-tert-butylphenoxide

OpenAIRE

Zaikov, Gennady; Volod’kin, Alexander

2010-01-01

The kinetics of catalytic alkylation of 2,6-ditert- butylphenol (ArOH) with methyl acrylate (MA) in the presence of potassium 2,6-di-tert-butylphenoxide (ArOK) depends on the method for the preparation of ArOK. The reaction ofArOH withKOHat temperatures > 453 Kaffords monomeric ArOK, which properties differ from those in the case of potassium 2,6-di-tert-butylphenoxide synthesized by the earliermethods.The regularities ofArOH alkylation depend ontheArOKconcentration, theArOH...

Determination of electron temperature and electron density in ...

African Journals Online (AJOL)

It is seen that the electron temperature increases from 5.8 × 102 oK to 7.83 × 104 oK as the pd is reduced from 130mm Hg × mm to 60 mm Hg × mm for argon. The electron densities increases from 2.8 × 1011/cm3 to 3.2 × 1011 /cm3 for the same variation of pds. For air the electron temperature increases from 3.6 × 104 oK to ...

A Carbon Flux Super Site. New Insights and Innovative Atmosphere-Terrestrial Carbon Exchange Measurements and Modeling

Energy Technology Data Exchange (ETDEWEB)

Leclerc, Monique Y. [The University of Georgia Research Foundation, Athens, GA (United States)

2014-11-17

This final report presents the main activities and results of the project “A Carbon Flux Super Site: New Insights and Innovative Atmosphere-Terrestrial Carbon Exchange Measurements and Modeling” from 10/1/2006 to 9/30/2014. It describes the new AmeriFlux tower site (Aiken) at Savanna River Site (SC) and instrumentation, long term eddy-covariance, sodar, microbarograph, soil and other measurements at the site, and intensive field campaigns of tracer experiment at the Carbon Flux Super Site, SC, in 2009 and at ARM-CF site, Lamont, OK, and experiments in Plains, GA. The main results on tracer experiment and modeling, on low-level jet characteristics and their impact on fluxes, on gravity waves and their influence on eddy fluxes, and other results are briefly described in the report.

Sucrose polyesters from poultry fat as non-ionic emulsifiers

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Megahed, Mohamed G.

2000-12-01

Full Text Available Poultry fats are rich in palmitic and oleic acids are produced as by-products from poultry industries. These fats can be utilized in the preparation of emulsifiers. Sucrose esters of poultry fat are prepared from low-cost poultry fat and sucrose by esterification. The yield of sucrose esters prepared in this work exceeds than 85%. The hydrophilic-lipophilic balance (HLB, surface tension, interfacial tension and stability index (SI were evaluated and compared with standard emulsifiers prepared from pure palmitate and oleate esters. Concerning the stability of emulsions, the values of interfacial tension and HLB were higher for the sucrose esters of poultry fat.Las grasas de aves de corral son ricas en ácidos palmítico y oleico y son producidas como subproductos de las industrias avícolas. Estas grasas pueden ser utilizadas en la preparación de emulsionantes. Los ésteres de sacarosa de grasas de aves de corral fueron preparadas a partir de grasas de bajo coste y sacarosa por esterificación. El rendimiento de los ésteres de sacarosa preparados en este trabajo superó el 85%. El balance hidrofílicolipofílico (HLB, tensión superficial, tensión interfacial e índice de estabilidad (SI fueron evaluados y comparados con emulsionantes estandar preparados de ésteres de palmitato y oleato puros. Los valores de tensión interfacial y el HLB fueron más altos en los poliésteres de sacarosa de las grasas de aves de corral.

Fatigue in Persian Gulf Syndrome - Physiologic Mechanisms

National Research Council Canada - National Science Library

Haller, Ronald

2000-01-01

...)Veterans matched for age, height and weight. Serum OK, incidence of elevated OK, and muscle histology and fatigue rate and level of oxygen uptake relative to 02 delivery during forearm exercise were similar in both groups...

A Quality-Centric Data Model for Distributed Stream Management Systems

OpenAIRE

Pietzuch, P; Fiscato, M; Vu, QH

2009-01-01

21.10.14 KB Ok to add published version to spiral. It is challenging for large-scale stream management systems to return always perfect results when processing data streams originating from distributed sources. Data sources and intermediate processing nodes may fail during the lifetime of a stream query. In addition, individual nodes may become overloaded due to processing demands. In practice, users have to accept incomplete or inaccurate query results because of failure or overload. In t...

Livestock Husbandry and Snow Leopard Conservation

NARCIS (Netherlands)

Mohammad, Ghulam; Mostafawi, Sayed Naqibullah; Dadul, Jigmet; Rosen, Tatjana; Mishra, Charudutt; Bhatnagar, Yash Veer; Trivedi, Pranav; Timbadia, Radhika; Bijoor, Ajay; Murali, Ranjini; Sonam, Karma; Thinley, Tanzin; Namgail, Tsewang; Prins, Herbert H.T.; Nawaz, Muhammad Ali; Ud Din, Jaffar; Buzdar, Hafeez

2016-01-01

Livestock depredation is a key source of snow leopard mortality across much of the species' range. Snow leopards break into livestock corrals, killing many domestic animals and thereby inflicting substantial economic damage. Locals may retaliate by killing the cat and selling its parts.

Simulation of hydrogen releases from fuel-cell vehicles in tunnels

Energy Technology Data Exchange (ETDEWEB)

Houf, William G.; Evans, Greg H.; James, Scott C. [Sandia National Labs., Livermore, CA (United States); Merilo, Erik; Groethe, Mark [SRI International, Menlo Park, CA (United States)

2010-07-01

Simulation results for a hydrogen fuel-cell vehicle in a full-scale tunnel have been performed for the case where hydrogen gas is vented from the vehicle as a result of thermal activation of the pressure relief device (PRD). The same modeling approach used in the full-scale tunnel modeling was validated in a scaled model by comparing simulated results with measured results from a series of scaled-tunnel test experiments performed at the SRI Corral Hollow test facility. Results of the simulations were found to be in good agreement with the experimental data. Finally, a rudimentary risk analysis indicated that the level of potential risk from hydrogen vehicles accidents involving thermally activated PRDs in tunnels does not appear to significantly increase the current level of individual risk to the public from everyday life. (orig.)

Chemical pleurodesis for prolonged postoperative air leak in primary spontaneous pneumothorax

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Cheng-Hung How

2014-05-01

Conclusion: Chemical pleurodesis using OK-432 or minocycline is safe and convenient for prolonged air leak after thoracoscopic treatment for PSP. Our experience suggested that OK-432 may be more effective than minocycline in reducing air leak.

Immortalisation with hTERT Impacts on Sulphated Glycosaminoglycan Secretion and Immunophenotype in a Variable and Cell Specific Manner.

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Tina P Dale

Full Text Available Limited options for the treatment of cartilage damage have driven the development of tissue engineered or cell therapy alternatives reliant on ex vivo cell expansion. The study of chondrogenesis in primary cells is difficult due to progressive cellular aging and senescence. Immortalisation via the reintroduction of the catalytic component of telomerase, hTERT, could allow repeated, longitudinal studies to be performed while bypassing senescent phenotypes.Three human cell types: bone marrow-derived stromal cells (BMA13, embryonic stem cell-derived (1C6 and chondrocytes (OK3 were transduced with hTERT (BMA13H, 1C6H and OK3H and proliferation, surface marker expression and tri-lineage differentiation capacity determined. The sulphated glycosaminoglycan (sGAG content of the monolayer and spent media was quantified in maintenance media (MM and pro-chondrogenic media (PChM and normalised to DNA.hTERT expression was confirmed in transduced cells with proliferation enhancement in 1C6H and OK3H cells but not BMA13H. All cells were negative for leukocyte markers (CD19, CD34, CD45 and CD73 positive. CD14 was expressed at low levels on OK3 and OK3H and HLA-DR on BMA13 (84.8%. CD90 was high for BMA13 (84.9% and OK3 (97.3% and moderate for 1C6 (56.7%, expression was reduced in BMA13H (33.7% and 1C6H (1.6%. CD105 levels varied (BMA13 87.7%, 1C6 8.2%, OK3 43.3% and underwent reduction in OK3H (25.1%. 1C6 and BMA13 demonstrated osteogenic and adipogenic differentiation but mineralised matrix and lipid accumulation appeared reduced post hTERT transduction. Chondrogenic differentiation resulted in increased monolayer-associated sGAG in all primary cells and 1C6H (p<0.001, and BMA13H (p<0.05. In contrast OK3H demonstrated reduced monolayer-associated sGAG in PChM (p<0.001. Media-associated sGAG accounted for ≥55% (PChM-1C6 and ≥74% (MM-1C6H.In conclusion, hTERT transduction could, but did not always, prevent senescence and cell phenotype, including

Cross-cultural adaptation and psychometric analysis of the Arabic version of the oxford knee score in adult male with knee osteoarthritis.

Science.gov (United States)

Alghadir, Ahmad H; Al-Eisa, Einas S; Anwer, Shahnawaz

2017-05-15

There are varieties of self-assessment questionnaire used for the evaluation of pain, functional disability, and health related quality of life in individuals with knee osteoarthritis (OA). The present study intended to adapt and translate the oxford knee score into the Arabic and investigated its psychometric properties in adult male with knee OA. Ninety-seven adult male (mean age 57.55 ± 11.49 years) with knee OA participated. Patients were requested to complete the adapted Arabic version of the Oxford knee score (OKS-Ar), reduced "Western Ontario and McMaster Universities Index (WOMAC)", and the Visual analogue scale (VAS). Patients were requested to complete 2 nd form of OKS-Ar at least 1 week apart to assess the reproducibility of the score. The OKS was adapted and translated into Arabic by two independent Arabic native speakers (one rehabilitation professional having experience of knee OA patients and another one a trained translator) according to the international guidelines. All the participants completed the 2 nd form of OKS-Ar (Response rate 100%). Reliability and internal consistency was high with an ICC of 0.97, and the Cronbach's alpha coefficient of 0.987, respectively. A significant relationship between the OKS-Ar and the WOMAC and VAS scores confirmed the construct validity (p < 0.001). The standard error of measurement (SEM) and the minimum detectable change (MDC) were 2.2 and 6.2, respectively. The adapted Arabic version of the OKS demonstrated acceptable psychometric properties, including reliability, internal consistency, and the validity. The present study indicates that the OKS-Ar is a suitable questionnaire to measure pain and physical function in the Arabic speaking adult male patients with knee OA.

Review: Christian Stegbauer (2001. Grenzen virtueller Gemeinschaft – Strukturen internetbasierter Kommunikationsforen [Boundaries of Virtual Communities—Structures of Internet-based Communication Fora

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Christian Carls

2004-01-01

Full Text Available Christian STEGBAUER discusses a common thesis for community development in the Internet as well as "popular destructuring fictions"—among them the assumption that in communication in virtual space "real life" origins, roles and status have no (or strongly reduced importance. The core of the book is the presentation of STEGBAUER's own empirical study on interaction patterns in selected mailing lists, reconstructed by means of quantitative analysis. The book contains interesting portrayals of classic models of community and group as well as one from the viewpoint of quantitative network analysis. While the means of quantification of this observation is creative and interesting, the reconstructed interaction structures, the identification of stronger central actors with high engagement in a wide variety of discussion threads, and patterns of discussions in sub-groups, are, in view of the size of most of the examined lists, not surprising. Due to the limits of analysis of interaction in mailing lists, the question about the possibility of virtual community in virtual space remains unanswered—if it is taken into consideration that interaction over various and functionally differentiated channels represents a success factor for virtual communities and groups. URN: urn:nbn:de:0114-fqs0401329

Optokinetic stimulation modulates neglect for the number space: Evidence from mental number interval bisection

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Konstantinos ePriftis

2012-02-01

Full Text Available Behavioral, neuropsychological, and neuroimaging data support the idea that numbers are represented along a mental number line (MNL, an analogical, visuo-spatial representation of number magnitude. The MNL is left-to-right oriented, with small numbers on the left and larger numbers on the right. Left neglect patients are impaired in processing the left side of the MNL and show a rightward deviation in the mental bisection of numerical intervals. In the present study we investigated the effects of optokinetic stimulation (OKS -a technique inducing spatial attention shifts by means of activation of the optokinetic nystagmus- on mental number interval bisection. One patient with left neglect following right hemisphere stroke (BG and four control patients with right hemisphere damage, but without neglect, performed the mental number interval bisection task in three experimental conditions of OKS: static, leftward, and rightward. In the static condition, BG misbisected to the right of the true midpoint. BG misbisected to the left following leftward OKS, but again to the right of the midpoint following rightward OKS. In contrast, the performance of controls was not significantly affected by the direction of OKS. We argue that shifts of visuospatial attention, induced by OKS, may affect the mental number interval bisection, suggesting the presence of an interaction between the processing of number magnitude and the processing of the perceptual space, in patients with neglect for the mental number space.

Getting Treatment for ADHD

Medline Plus

Full Text Available ... and Reimbursement Early Career Psychiatrists Education Center Ethics International Job Source Life Members Maintenance of Certification Resources ... My Profile Donate About AACAP Copyright © Advanced Solutions International . {1} ##LOC[OK]## {1} ##LOC[OK]## ##LOC[Cancel]## { ...

Combination therapy of radiation and immunomodulators in the treatment of MM46 tumor transplanted in C3H/He mice

International Nuclear Information System (INIS)

Miyaji, Chihiro; Imanaka, Kazufumi; Gose, Kyuhei; Ichiyanagi, Akihiro; Imajo, Yoshinari

1983-01-01

Female C3H/He mice aged 13 weeks with transplanted MM 46 tumor were used in histological and enzymohistochemical studies on the timing of administration of immunomodulators, PSK (a protein bound polysaccharide prepared from Coriolus versicolor), or OK-432 (Streptococcal preparation) combined with two fractionated local irradiation with the total dose of 3,000 rad. The daily dose of 250 mg/kg of PSK, or 1 KE/mouse of OK-432 was respectively injected intraperitoneally for four consecutive days before or after irradiation. Mice were sacrificed before irradiation and 7, 14 and 21 days after irradiation. Resected tumor tissues were examined using H-E staining and α-naphtyl acetate esterase (ANAE) staining to observe the stromal reactions such as the infiltration of mononuclear cells and fibroblasts around tumor tissues. When PSK or OK-432 was administered after irradiation, remarkable lymphocytic infiltration was observed compared with the control group and the group to which PSK or OK-432 was administered before irradiation. ANAE staining revealed most of infiltrating lymphocytes were T-cells. These results suggested that PSK and OK-432 which were received after radiotherapy enhanced the immunological responses against tumors which were represented by remarkable lymphocytic infiltration. (author)

Combination therapy of radiation and immunomodulators in the treatment of MM46 tumor transplanted in C3H/He mice. Histological and histoenzymatic studies using alpha-naphtyl acetate esterase staining

Energy Technology Data Exchange (ETDEWEB)

Miyaji, Chihiro; Imanaka, Kazufumi; Gose, Kyuhei; Ichiyanagi, Akihiro; Imajo, Yoshinari (Kobe Univ. (Japan). School of Medicine)

1983-12-01

Female C3H/He mice aged 13 weeks with transplanted MM 46 tumor were used in histological and enzymohistochemical studies on the timing of administration of immunomodulators, PSK (a protein bound polysaccharide prepared from Coriolus versicolor), or OK-432 (Streptococcal preparation) combined with two fractionated local irradiation with the total dose of 3,000 rad. The daily dose of 250 mg/kg of PSK, or 1 KE/mouse of OK-432 was respectively injected intraperitoneally for four consecutive days before or after irradiation. Mice were sacrificed before irradiation and 7, 14 and 21 days after irradiation. Resected tumor tissues were examined using H-E staining and ..cap alpha..-naphtyl acetate esterase (ANAE) staining to observe the stromal reactions such as the infiltration of mononuclear cells and fibroblasts around tumor tissues. When PSK or OK-432 was administered after irradiation, remarkable lymphocytic infiltration was observed compared with the control group and the group to which PSK or OK-432 was administered before irradiation. ANAE staining revealed most of infiltrating lymphocytes were T-cells. These results suggested that PSK and OK-432 which were received after radiotherapy enhanced the immunological responses against tumors which were represented by remarkable lymphocytic infiltration.

Performative Research in Art Education: Scenes from the Seminar "Exploring Performative Rituals in City Space"

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Ulrike Stutz

2008-05-01

Full Text Available In my contribution, I lay the foundations for a performative approach to art education research and then apply it to three examples from a performance seminar conducted with university students. In the process, I subject video documentaries produced during performative exploration of everyday rituals in public space, to a fresh performative analysis using media techniques. My research interest targets the reactions of passers-by as an expanded audience, i.e., it targets the qualitative changes of social space brought about by these actions of site specific art. The contribution is presented as a multimedia document with videos and animations. The parallel presentation of different media formats produces differentiating and activating readings. URN: urn:nbn:de:0114-fqs0802514

Qualitative Research Networking: FQS as an Example

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Katja Mruck

2000-12-01

Full Text Available If one thinks about accessing and reusing qualitative data with an international and interdisciplinary perspective, this topic also contains organisational and networking tasks beyond the field of qualitative archiving in the narrow sense—some of them necessarily relying on the Internet and its tools. I had the chance to gain experiences within international networking while editing the online journal FQS and I would like to summarise some aspects, hopefully helpful also for the planned networking of qualitative archives within INQUADA. So let me first shortly introduce FQS—its origin and its current state—, and afterwards I will stress some opportunities and also some challenges, FQS and similar networking projects confront. URN: urn:nbn:de:0114-fqs0003346

FQS—From the Shop floor

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Katja Mruck

2001-05-01

Full Text Available Two years of FQS—this means two years of intense publishing and networking efforts in the field of qualitative research, using various Internet services. In this article, we will take stock of some of the foundations and cornerstones of this work, which resulted in the current project, allowing us to re-organize FQS to become an international and interdisciplinary online gateway for qualitative research and social sciencesŽ Internet use—funded by the Deutsche Forschungsgemeinschaft. Additionally, we will provide readers with a first overview of this new, fifth "Special Issue: FQS Reviews." We also provide information about some innovations accomplished within this Issue and some expectations for the future are described as well. URN: urn:nbn:de:0114-fqs010283

Review: Zygmunt Bauman (2005. Verworfenes Leben. Die Ausgegrenzten der Moderne [Wasted Lives: Modernity and Its Outcasts

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Martin Spetsmann-Kunkel

2007-09-01

Full Text Available Zygmunt BAUMAN delivers in his book Wasted Lives: Modernity and Its Outcasts a graphic and pessimistic description of ostracism in contemporary society. In the first part the outcasts of modern society are described, following market logic, as superfluous. Part two traces the actions of the state in punishing and segregating those who are ostracised. Finally, the involvement of those who are not (yet ostracised is depicted as somewhat fragile, with instability and lack of commitment as central characteristics of our liquid modernity. The fear of losing social status and thus becoming useless is inherent in life in modern society. This review ends with a few brief reflections on possible connections between BAUMAN's analysis and social research projects. URN: urn:nbn:de:0114-fqs0703295

Review: Henry E. Brady & David Collier (Eds. (2004. Rethinking Social Inquiry: Diverse Tools, Shared Standards

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Matthias Catón

2006-03-01

Full Text Available The book Rethinking Social Inquiry, edited by Henry E. BRADY and David COLLIER, is a response to a book by KING, KEOHANE and VERBA (1994 that aimed to introduce quantitative standards to qualitative research. The authors of the book reviewed here criticize many of the suggestions made there because they argue that qualitative research requires other tools. Nevertheless, they agree that the foundations of research design are similar. The book comprises a comprehensive critique of mainstream quantitative techniques, describes a set of qualitative tools for research, and addresses issues of how to combine qualitative and quantitative approaches to maximize analytical leverage. It is an excellent contribution to the methodological debate in the social sciences. URN: urn:nbn:de:0114-fqs0602309

Review: Anne Waldschmidt & Werner Schneider (Eds. (2007. Disability Studies, Kultursoziologie und Soziologie der Behinderung [Disability Studies, Cultural Sociology and the Sociology of Disability: Explorations of a New Research Field

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Lisa Pfahl

2008-07-01

Full Text Available This book contains 13 articles and gives an overview of German disability studies in relation to theory, research perspectives and research results. It contains theoretical approaches to the theory of disability and introduces the reader to empirical research on the body and on cultures of disability. Cross-national approaches and analyses of the social and political situation give information on the situation of people with disabilities in Germany as well as internationally. The book discusses the recent debate on the social construction of disability in German academia. It also contributes to the new Anglo-American theoretical debate about the governmentality of disabilty and, for example, problematizes findings about blindness, personal assistance and segregation within the educational system. URN: urn:nbn:de:0114-fqs0803215

Conference Report: Rechtsextremismusforschung – aktuelle Tendenzen empirischer Untersuchungen [Research on Right-wing Extremism—Latest Trends in Empirical Studies

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Janina Söhn

2004-01-01

Full Text Available During this workshop scholars presented new, mainly empirical studies which explored different aspects of right-wing extremism in Germany. While a number of talks focused on political strategies and modern forms of organization of local neo-Nazi scenes, political elites and the music industry, others had chosen a biographical view on the personal development of young right-wing extremists. Studies on the local context of and conditions for right-wing extremist actions were complemented by representative survey data on political attitudes of German citizens. Apart from discussions about the phenomenon of right-wing extremism itself, participants had the opportunity to exchange their experience of doing empirical qualitative research in a dangerous field. URN: urn:nbn:de:0114-fqs0401215

Los docentes universitarios y su concepción sobre el aprendizaje, la autorregulación y la personalización educativa. Un análisis desde la teoría fundamentada

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Florencia Teresita Daura Toyos

2014-05-01

Full Text Available Se presentan los resultados de una investigación en la que se efectuaron entrevistas semiestructuradas en profundidad a los docentes responsables de asignaturas del Ciclo Clínico de la carrera de Medicina que se dicta en una universidad privada y otra estatal. Los datos recogidos se analizaron a partir del modelo ofrecido por la teoría fundamentada (STRAUSS & CORBIN 1998 con el objeto de elaborar una interpretación sobre cuál es la concepción que los profesores poseen sobre tres conceptos que se consideran centrales en el proceso educativo: el aprendizaje, la capacidad autorreguladora y la personalización. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs140289

Review: Joachim R. Höflich (2003. Mensch, Computer und Kommunikation. Theoretische Verortungen und empirische Befunde [Man, Computer, Communication. Theoretical Positions and Empirical Findings

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Jan Schmidt

2004-05-01

Full Text Available Joachim R. HÖFLICH presents a theory of the institutionalization of computer-mediated communication that centers on the user and his/her expectations. "Computer frames", consisting of rules and routines for the appropriate use of a medium and its applications as a tool for information, public discussion or interpersonal communication, structure the single usage episodes as well as the users' expectations. Drawing on a variety of data on the development of the Newspaper-Mailbox "Augsburg Newsline" in the Mid-Nineties, HÖFLICH demonstrates the usefulness of his conceptual framework for empirical analysis. His book is, therefore, a valuable contribution to the field of online research in social and communication science alike. URN: urn:nbn:de:0114-fqs040297

The Diverse Worlds and Research Practices of Qualitative Software

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Nigel Fielding

2012-05-01

Full Text Available The article considers the way that digital research technologies and online environments increasingly support new forms of qualitative research that have emerged as a result of new user groups taking up the practice of social research. New practitioners of qualitative research have entered the field from societies where qualitative research is a newly-established practice, and new cadres of "citizen researchers" have turned to qualitative methods for non-academic purposes. These groups challenge accepted understandings of qualitative methods. The article uses the example of qualitative software as a case study of how qualitative research is enabled by new digital tools that help new user groups extend the application of qualitative research methods. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1202124

Cultural and Corporate Belonging in the Course of Transnational Biographies: A Case Study of a Sierra Leonean Immigrant in Germany

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Jan Küver

2009-09-01

Full Text Available How does cultural and corporate affiliation emerge in transnational biographies? How does it develop under the influence of global and national power structures? These questions are addressed in this study that combines epistemological approaches dealing with the interplay of social and individual factors in identity formation with a structural analysis of historical power relations in form of racism and colonialism. Empirically this paper identifies how immigrants deal with challenges of integration into the host society and incorporate these experiences into their biographical self-construction. It concentrates on African and particularly Sierra Leonean immigrants in Germany. The findings are generated from a reconstructive analysis of selected biographical narrations which were scrutinized from different perspectives. URN: urn:nbn:de:0114-fqs0903234

The Analysis of Heterogeneous Text Documents with the Help of the Computer Program NUD*IST

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Christine Plaß

2000-12-01

Full Text Available On the basis of a current research project we discuss the use of the computer program NUD*IST for the analysis and archiving of qualitative documents. Our project examines the social evaluation of spectacular criminal offenses and we identify, digitize and analyze documents from the entire 20th century. Since public and scientific discourses are examined, the data of the project are extraordinarily heterogeneous: scientific publications, court records, newspaper reports, and administrative documents. We want to show how to transfer general questions into a systematic categorization with the assistance of NUD*IST. Apart from the functions, possibilities and limitations of the application of NUD*IST, concrete work procedures and difficulties encountered are described. URN: urn:nbn:de:0114-fqs0003211

Review: Rainer Diaz-Bone (2002. Kulturwelt, Diskurs und Lebensstil [Cultural World, Discourse and Life Style

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Johannes Angermüller

2004-01-01

Full Text Available In his work on the discourse of popular music DIAZ-BONE opens BOURDIEU's theory of distinction to a discursive approach. Analyzing the discourse of German heavy metal and techno zines, the author demonstrates the usefulness of a theory of discourse based on the notion of difference and opposition for the sociology of culture. He criticizes BOURDIEU for his reductionist tendency and underlines the relative autonomy of discursive patterns for establishing a system of hierarchical cultural values. In his analysis DIAZ-BONE finds that the discourse about heavy metal music gives, amongst others, a prominent role to "authenticity" and "artisan solidity", whereas the discourse about techno DJs rather highlights technical innovation and cultural networking. URN: urn:nbn:de:0114-fqs040126

Review: Gregory C. Stanczak (Ed. (2007. Visual Research Methods

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Boris Traue

2009-03-01

Full Text Available In this edited volume, research methods employing the camera as a means of documentation in the context of ethnographic research are presented and discussed. To a lesser extent, the volume deals with research strategies for dealing with images produced by social actors, such as propaganda photography and video diaries. Special attention is given to the way the camera facilitates the process of communication in ethnographic research. This collection may be very helpful for readers looking for a discussion of methodological problems and practical advice for the use of cameras, especially in the context of ethnographic research. Theoretical issues of visuality and visual performance in contemporary societies are mentioned, but not treated in depth. URN: urn:nbn:de:0114-fqs090265

The Dance of the Now—Poetics of Everyday Human Movement

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Lis Engel

2008-05-01

Full Text Available The inspiration for this paper comes from an interest in the living movement of everyday life and from an interest in the stories of the felt sense of embodiment, subjectivity and culture. A phenomenological approach is used to get an embodied and experiential understanding of sensitive form and meaning. How are embodiment as performance of expressive form and cultural identities interwoven? How are intersubjectivity and culture performed? The living body images are analysed from an aesthetic-phenomenological perspective highlighting the living body as an inter-subjective, "vibrational" field that deepens the experiential understanding of everyday movement as performance of dynamic repertoires of existence. These become everyday events expressed as the dance of the now. URN: urn:nbn:de:0114-fqs0802355

Review: Franz Breuer with Assistance of Barbara Dieris and Antje Lettau (2009. Reflexive Grounded Theory. Eine Einführung für die Forschungspraxis [Reflexive Grounded Theory: An Introduction to Research Praxis

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Sandra Da Rin

2010-03-01

Full Text Available This textbook by Franz BREUER, produced with the assistance of Barbara DIERIS and Antje LETTAU, is of interest more for the introduction it provides to reflexive research praxis than to grounded theory methodology. This means the subjectivity of the researcher is included in the research process as a decisive source of cognition. Reflexive grounded theory methodology is characterized by three elements that also structure the textbook. In the present review, I focus on two of these in detail: the approach to the research field based on ethnography, particular its epistemological prerequisites, and the inclusion of (self- reflexivity. The latter points to questions that are addressed at the end of this review. URN: urn:nbn:de:0114-fqs1002140

Gender, Reflexivity, and Positionality in Male Research in One's Own Community With Filipino Seafarers' Wives

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Roderick G. Galam

2015-07-01

Full Text Available This article reflects on the epistemological, methodological, and ethical issues related to undertaking a cross-gender research (male researcher with female participants in one's own community. It also examines issues of analysis and representation germane to taking a gendered perspective in this study of the lives and experiences of left-behind women. The article frames the discussion of these issues within four interrelated sites or levels of reflexivity: theoretical reflexivity, gender and fieldwork relations, positionality and the insider/outsider dynamic, and representation. The conclusion reflects on the ethical obligation a researcher conducting a study in one's own community bears and the consequences of this ethical burden on representation. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1503139

Review: Heide von Felden (Ed. (2007. Methodendiskussion in der Biographieforschung [Methodological Issues in Biographical Research: Classical and Innovative Perspectives on Qualitative Analysis

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Klaus Heuer

2008-10-01

Full Text Available This article assesses the extent to which the book under review lives up to the expectations raised by its title. The focus is thus on whether the results of interpreting the five featured case studies justify the methodological effort. The interaction between the text and the reader is left out and this is problematic when it comes to interpreting the memories of the Jewish emigrant who is at the centre of three out of the five essays. Furthermore, it is clear that on a formal level (relating to the shared analytical subject as well as in terms of content (relating to interconnectedness that the methodological discussion falls short of the requirements of the approach taken. URN: urn:nbn:de:0114-fqs0901193

Ethical Considerations for Teacher-Education Researchers of Coteaching

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Stephen M. Ritchie

2006-09-01

Full Text Available In small-scale studies of coteaching, there are few genuine ethical dilemmas for researchers providing participants are engaged in ongoing dialogue about the purposes and emerging results of the research. When studies are up-scaled for teacher education programs, the territory is uncharted. This adds uncertainty about the ethical codes of practice for a teacher education program director who initiates such research. If the research is likely to lead to valued learning experiences for participating interns without harm to other participants, it may be ethical to proceed. In this paper I suggest that even though getting the balance right will continue to challenge researchers, it will be essential to establish and maintain dialogue between all participants. URN: urn:nbn:de:0114-fqs0604218

Review: Michalis Kontopodis & Jörg Niewöhner (Eds. (2010. Das Selbst als Netzwerk. Zum Einsatz von Körpern und Dingen im Alltag [The Self as Network: On Everyday Uses of Bodies and Things

Directory of Open Access Journals (Sweden)

Niklas Alexander Chimirri

2012-03-01

Full Text Available In the investigation of human everyday life, the significance of the material still tends to be neglected. The anthology edited by KONTOPODIS and NIEWÖHNER presents contributions that draw on relational-materialist concepts in order to praxiographically study how both human and non-human agents transform (mostly biomedical everyday practices. This review attempts to connect these material-semiotic descriptions to a critical psychological perspective. It highlights how the contributions' focus on material things' actions is valuable for further unraveling the human-world relationship. Meanwhile it questions whether the underlying conceptual framework allows for an emancipatory science which strives for transformations that reach beyond the mere descriptive level. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs120270

To the Top. Micropolitics of Career Planning of Social Scientists

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Jo Reichertz

2004-05-01

Full Text Available Science is a peculiar field of profession—with changing features depending on changing values and the role of media. The aim of this article is to demonstrate the current development in the field of German social scientists concerning the new conception of raising German higher education and science to the international standard. The introduction of associate professorship (Junior Professor, the standardization of departments at universities and the new way of distributing resources include only a few of the important factors that contribute in changing the values in science. As a result promising young scientists need to put much more scientific effort and much more micropolitics to work their way up and to get to the top. URN: urn:nbn:de:0114-fqs0402165

Disease: H01471 [KEGG MEDICUS

Lifescience Database Archive (English)

Full Text Available HORS ... Ogita S, Tsuto T, Nakamura K, Deguchi E, Tokiwa K, Iwai N ... TITLE ... OK-432 therapy for lymphangioma in child...Rautio R, Rautiainen M, Airaksinen M ... TITLE ... OK-432 (Picibanil) therapy for lymphangiomas in children. ...

Influence of grazing regimes on cattle nutrition and performance and vegetation dynamics in Sahelian rangelands

NARCIS (Netherlands)

Ayantunde, A.A.

1998-01-01

In the West African Sahel, common herd management practices such as night grazing and corralling influence time available for grazing. When animals are used to deposit manure in the cropping fields, conflicts often arise between the need for animals to graze long enough for adequate feed

78 FR 53391 - Endangered and Threatened Wildlife; 90-Day Finding on a Petition To Delist the North Pacific...

Science.gov (United States)

2013-08-29

..., address, etc.) voluntarily submitted may be publicly accessible. Do not submit confidential business... that a petition need not establish a strong likelihood or a high probability that the petitioned [[Page... involving the creation of bubble structures to trap and corral fish; bubble nets, clouds and curtains are...

CURRAIS E VACARIAS NA CIDADE

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Doralice Sátyro Maia

2005-01-01

Full Text Available The text presents some results of the research Slow times in the city: permanence and changes of rural customs in the city of João Pessoa-Pb.It focuses on the analysis of rural sub-spaces found in the city, specially in corrals and cowsheds.The investigation comprised the mapping of those spaces in the urban network, the internal arrangement and the analysis of customs, production and marketing of "in natura" milk. With these records, the permanence and changes in the city were clarified. Both the bibliographical reading and the information collection in newspapers and in research and statistical institutions were fundamental to recover the process of milk distribution and the moment of greater pressure on the producers in the Brazilian cities. Besides, the research uses the field-work, obtaining data through interviews and testimonies. Such methodological procedures permitted to understand the permanence and changes of corrals and cowsheds in the city of João Pessoa- Pb.

Porcine Cysticercosis: Possible Cross-Reactivity of Taenia hydatigena to GP50 Antigen in the Enzyme-Linked Immunoelectrotransfer Blot Assay.

Science.gov (United States)

Muro, Claudio; Gomez-Puerta, Luis A; Flecker, Robert H; Gamboa, Ricardo; Barreto, Percy Vilchez; Dorny, Pierre; Tsang, Victor C W; Gilman, Robert H; Gonzalez, Armando E; Garcia, Hector H; O'Neal, Seth E; For The Cysticercosis Working Group In Peru

2017-12-01

The lentil lectin glycoprotein enzyme-linked immunoelectrotransfer blot (LLGP EITB, reported sensitivity 99% and specificity 100%) is used as a serologic marker of exposure to Taenia solium in pigs. However, only a limited number of parasites have been evaluated for cross reactivity. Pigs may host other related cestode infections, including Taenia hydatigena, which have not been formally evaluated for cross-reactions. We investigated a corral in Tumbes, Peru, a region where a cysticercosis elimination demonstration project was completed in 2012. In this corral, 14/19 (73.7%) 6-8-week-old piglets were reactive to GP50 on LLGP EITB, and all had circulating Taenia sp. antigens. From eight necropsied piglets; four were infected with T. hydatigena metacestodes whereas none had evidence of T. solium infection. Two resident dogs were subsequently confirmed to have T. hydatigena taeniasis. These results suggest GP50 cross-reactivity in T. hydatigena- infected pigs, although controlled experimental infection is needed to confirm this hypothesis.

Wright-Fisher diffusion bridges.

Science.gov (United States)

Griffiths, Robert C; Jenkins, Paul A; Spanò, Dario

2017-10-06

The trajectory of the frequency of an allele which begins at x at time 0 and is known to have frequency z at time T can be modelled by the bridge process of the Wright-Fisher diffusion. Bridges when x=z=0 are particularly interesting because they model the trajectory of the frequency of an allele which appears at a time, then is lost by random drift or mutation after a time T. The coalescent genealogy back in time of a population in a neutral Wright-Fisher diffusion process is well understood. In this paper we obtain a new interpretation of the coalescent genealogy of the population in a bridge from a time t∈(0,T). In a bridge with allele frequencies of 0 at times 0 and T the coalescence structure is that the population coalesces in two directions from t to 0 and t to T such that there is just one lineage of the allele under consideration at times 0 and T. The genealogy in Wright-Fisher diffusion bridges with selection is more complex than in the neutral model, but still with the property of the population branching and coalescing in two directions from time t∈(0,T). The density of the frequency of an allele at time t is expressed in a way that shows coalescence in the two directions. A new algorithm for exact simulation of a neutral Wright-Fisher bridge is derived. This follows from knowing the density of the frequency in a bridge and exact simulation from the Wright-Fisher diffusion. The genealogy of the neutral Wright-Fisher bridge is also modelled by branching Pólya urns, extending a representation in a Wright-Fisher diffusion. This is a new very interesting representation that relates Wright-Fisher bridges to classical urn models in a Bayesian setting. Copyright © 2017 Elsevier Inc. All rights reserved.

Modeling of coated fuel particles irradiation behavior

International Nuclear Information System (INIS)

Liang Tongxiang; Phelip, M.

2006-01-01

In this report, PANAMA code was used to estimate the CP performance under normal and accident condition. Under the normal irradiation test (1000 degree C 625 efpd, 10% FIMA), for intact CP fuel, failure fraction is in the level of 10 -7 . As-fabricated SiC failed particles results in the through coatings failed particles much earlier than the intact particles does, OPyC layer does not fail immediately after irradiation starts. The significant failures start at beyond the burnup of about 7% FIMA. Under the accident condition, the calculated results showed that when the heating temperature is much higher than 1850 degree C, the failure fraction of coated particle can reach the level of 1 percent. The CP fuel fails significantly if it has a buffer layer thinner than 65 urn, SiC layer thinner than 30 μm. High burnup CP need to develop small size kernel, thick buffer layer and thick SiC layer. (authors)

MODELLING THE DYNAMICS OF ANTIBODY PRODUCTION IN BIRDS

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ANDRÉS OLARTE

2011-01-01

Full Text Available En este artículo se presenta un modelo dinámico de la respuesta inmune humoral de aves para la producción de anticuerpos específi cos. Los anticuerpos son fundamentales para la investigación, diagnóstico y tratamiento de diversas enfermedades. Se ha reconocido que los anticuerpos obtenidos de aves de corral son una opción efi ciente para aplicaciones en medicina y biología. Por tanto, un modelo que represente la dinámica de este proceso resulta de gran utilidad. El modelo está compuesto de siete ecuaciones diferenciales ordinarias, no lineales, con coefi cientes constantes y representa las principales poblaciones celulares y moleculares de la respuesta inmune de las aves. Los parámetros se obtuvieron a partir de datos reportados en el área de inmunología aviar y mamífera. Las respuestas obtenidas "in silico" en términos de la concentración de anticuerpos se presentan y se comparan contra la cinética reportada.

Two-Phase Contiguous Supported Lipid Bilayer Model for Membrane Rafts via Polymer Blotting and Stenciling.

Science.gov (United States)

Richards, Mark J; Daniel, Susan

2017-02-07

The supported lipid bilayer has been portrayed as a useful model of the cell membrane compatible with many biophysical tools and techniques that demonstrate its appeal in learning about the basic features of the plasma membrane. However, some of its potential has yet to be realized, particularly in the area of bilayer patterning and phase/composition heterogeneity. In this work, we generate contiguous bilayer patterns as a model system that captures the general features of membrane domains and lipid rafts. Micropatterned polymer templates of two types are investigated for generating patterned bilayer formation: polymer blotting and polymer lift-off stenciling. While these approaches have been used previously to create bilayer arrays by corralling bilayers patches with various types of boundaries impenetrable to bilayer diffusion, unique to the methods presented here, there are no physical barriers to diffusion. In this work, interfaces between contiguous lipid phases define the pattern shapes, with continuity between them allowing transfer of membrane-bound biomolecules between the phases. We examine effectors of membrane domain stability including temperature and cholesterol content to investigate domain dynamics. Contiguous patterning of supported bilayers as a model of lipid rafts expands the application of the SLB to an area with current appeal and brings with it a useful toolset for characterization and analysis. These combined tools should be helpful to researchers investigating lipid raft dynamics and function and biomolecule partitioning studies. Additionally, this patterning technique may be useful for applications such as bioseparations that exploit differences in lipid phase partitioning or creation of membranes that bind species like viruses preferentially at lipid phase boundaries, to name a few.

METALLICITY AND TEMPERATURE INDICATORS IN M DWARF K-BAND SPECTRA: TESTING NEW AND UPDATED CALIBRATIONS WITH OBSERVATIONS OF 133 SOLAR NEIGHBORHOOD M DWARFS

Energy Technology Data Exchange (ETDEWEB)

Rojas-Ayala, Barbara [Department of Astrophysics, American Museum of Natural History, Central Park West at 79th Street, New York, NY 10024 (United States); Covey, Kevin R.; Lloyd, James P. [Department of Astronomy, Cornell University, 122 Sciences Drive, Ithaca, NY 14853 (United States); Muirhead, Philip S., E-mail: babs@amnh.org [Department of Astronomy, California Institute of Technology, 1200 East California Boulevard, MC 249-17, Pasadena, CA 91125 (United States)

2012-04-01

We present K-band spectra for 133 nearby (d < 33 ps) M dwarfs, including 18 M dwarfs with reliable metallicity estimates (as inferred from an FGK type companion), 11 M dwarf planet hosts, more than 2/3 of the M dwarfs in the northern 8 pc sample, and several M dwarfs from the LSPM catalog. From these spectra, we measure equivalent widths of the Ca and Na lines, and a spectral index quantifying the absorption due to H{sub 2}O opacity (the H{sub 2}O-K2 index). Using empirical spectral type standards and synthetic models, we calibrate the H{sub 2}O-K2 index as an indicator of an M dwarf's spectral type and effective temperature. We also present a revised relationship that estimates the [Fe/H] and [M/H] metallicities of M dwarfs from their Na I, Ca I, and H{sub 2}O-K2 measurements. Comparisons to model atmosphere provide a qualitative validation of our approach, but also reveal an overall offset between the atomic line strengths predicted by models as compared to actual observations. Our metallicity estimates also reproduce expected correlations with Galactic space motions and H{alpha} emission line strengths, and return statistically identical metallicities for M dwarfs within a common multiple system. Finally, we find systematic residuals between our H{sub 2}O-based spectral types and those derived from optical spectral features with previously known sensitivity to stellar metallicity, such as TiO, and identify the CaH1 index as a promising optical index for diagnosing the metallicities of near-solar M dwarfs.

Bullying: It's Not OK

Science.gov (United States)

... and generally feel helpless. Facts About Bullying Both girls and boys can be bullies. Bullies target children who cry, ... teasing, threatening, or hurting someone. All children can learn to treat others ... with others. Together with the school principal, teachers, counselors, and parents ...

Is the interface OK?

Digital Repository Service at National Institute of Oceanography (India)

Suresh, T.

When a peripheral device fails, software methods can be initially resorted to before the usual hardware test procedures are used. A test program is presented here that allows various peripherals, inter-faced to a Norsk Data computer, to be tested...

78 FR 38072 - General Management Plan, Final Environmental Impact Statement, Guadalupe Mountains National Park...

Science.gov (United States)

2013-06-25

...[aacute]squez, at the Park Headquarters/Pine Springs Visitor Center: 400 Pine Canyon Drive, Salt Flat, TX...]squez, Superintendent, Guadalupe Mountains National Park, HC 60, Box 400, Salt Flat, TX 79847-9400.... Campsites and horse corrals would be closed and their sites revegetated. The limited amount of new...

SRTM Colored Height and Shaded Relief: Corral de Piedra, Argentina

Science.gov (United States)

2001-01-01

Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) that flew twice on the Space Shuttle Endeavour in 1994. SRTM was designed to collect three-dimensional measurements of the Earth's surface. To collect the 3-D data, engineers added a 60-meter-long (200-foot) mast, installed additional C-band and X-band antennas, and improved tracking and navigation devices. The mission is a cooperative project between the National Aeronautics and Space Administration (NASA), the National Imagery and Mapping Agency (NIMA) of the U.S. Department of Defense, and the German and Italian space agencies. It is managed by NASA's Jet Propulsion Laboratory, Pasadena, CA, for NASA's Earth Science Enterprise, Washington, DC.Size: 57.6 x 40.5 kilometers ( 35.7 x 25.1 miles) Location: 40.4 deg. South lat., 70.8 deg. West lon. Orientation: North toward the top Image Data: Shaded and colored SRTM elevation model Date Acquired: February 2000

Optokinetic and vestibular stimulation determines the spatial orientation of negative optokinetic afternystagmus in the rabbit.

Science.gov (United States)

Pettorossi, V E; Errico, P; Ferraresi, A; Barmack, N H

1999-02-15

Prolonged binocular optokinetic stimulation (OKS) in the rabbit induces a high-velocity negative optokinetic afternystagmus (OKAN II) that persists for several hours. We have taken advantage of this uniform nystagmus to study how changes in static head orientation in the pitch plane might influence the orientation of the nystagmus. After horizontal OKS, the rotation axis of the OKAN II remained almost constant in space as it was kept aligned with the gravity vector when the head was pitched by as much as 80 degrees up and 35 degrees down. Moreover, during reorientation, slow-phase eye velocity decreased according to the head pitch angle. Thereafter, we analyzed the space orientation of OKAN II after optokinetic stimulation during which the head and/or the OKS were pitched upward and downward. The rotation axis of OKAN II did not remain aligned with an earth vertical axis nor a head vertical axis, but it tended to be aligned with that of the OKS respace. The slow-phase eye velocity of OKAN II was also affected by the head pitch angle during OKS, because maximal OKAN II velocity occurred at the same head pitch angle as that during optokinetic stimulation. We suggest that OKAN II is coded in gravity-centered rather than in head-centered coordinates, but that this coordinate system may be influenced by optokinetic and vestibular stimulation. Moreover, the velocity attenuation of OKAN II seems to depend on the mismatch between the space-centered nystagmus rotation axis orientation and that of the "remembered" head-centered optokinetic pathway activated by OKS.

Getting Treatment for ADHD

Medline Plus

Full Text Available ... ADHD? Common Signs and Symptoms Getting Treatment Supporting School Success The Teenage Years Working Together Resources Connect With Us Contact Us info@advsol.com My Profile Donate About AACAP Copyright © Advanced Solutions International . {1} ##LOC[OK]## {1} ##LOC[OK]## ##LOC[Cancel]## { ...

Getting Treatment for ADHD

Medline Plus

Full Text Available ... Common Signs and Symptoms Getting Treatment Supporting School Success The Teenage Years Working Together Resources Connect With Us Contact Us info@advsol.com My Profile Donate About AACAP Copyright © Advanced Solutions International . {1} ##LOC[OK]## {1} ##LOC[OK]## ##LOC[Cancel]## { ...

Increased tumor uptake of 67Ga citrate following a course of picibanil (NSC-B116209)

International Nuclear Information System (INIS)

Okuyama, Shinichi; Matsuzawa, Taiju; Mishina, Hitoshi.

1979-01-01

Exposure to exponential dose schedules of OK-432, penicillin-inactivated preparation of streptococcus hemolyticus (NSC-B116209), resulted in an increased retention of 67 Ga citrate. Its uptake in footpad tumors of AH 109A was also increased. The results may suggest that pretreatment with OK-432 would increase tumor uptake of 67 Ga citrate and help scintigraphic delineation of malignancies in man. It may probably augment tumor concentration of anticancer chemotherapeutics, too. Thus, the tumor affinitive property of OK-432 can be taken advantage of in anticancer strategy as well as cancer detection by 67 Ga scanning. (author)

Evaluation of concomitant use of non-specific immunopotentiator on 172 cases of primary lung cancer (Stage III, IV) treated with radiation combined with chemotherapy

International Nuclear Information System (INIS)

Ogawa, Yasuhiro; Kimura, Shuji; Imajo, Yoshinari; Hamada, Fumio; Miyaji, Chihiro

1982-01-01

The clinical effect of concomitant use of non-specific immunopotentiator OK-432 and/or PSK was studied about 172 cases of primary lung cancer (Stage III, IV). In 91 cases in stage III, fifty percent survival period was found to be 11.5 months for 63 cases with OK-432 and/or PSK, and 7.5 months for 28 cases without immunotherapy, respectively. In 81 cases in stage IV, fifty percent survival period was found to be 6.7 months for 45 cases with OK-432 and/or PSK, and 3.3 months for 36 cases without immunotherapy, respectively. (author)

Southern Hemisphere Measurement of the Anisotropy in the CosmicMicrowave Background Radiation

Energy Technology Data Exchange (ETDEWEB)

Smoot, George F.; Lubin, Phil M.

1979-06-01

A recent measurement of the anisotropy in the Cosmic Background Radiation from the southern hemisphere (Lima, Peru) is essentially in agreement with previous measurements from the northern hemisphere. The net anisotropy can be described as a first order spherical harmonic (Doppler) anisotropy of amplitude 3.1 {+-} 0.4 m{sup o}K with a quadrupole anisotropy of less than 1 m{sup o}K. In addition, measurements of the linear polarization yield an upper limit of 1 m{sup o}K, or one part in 3000, at 95% C.L. for the amplitudes of any spherical harmonic through third order.

Face Prediction Model for an Automatic Age-invariant Face Recognition System

OpenAIRE

Yadav, Poonam

2015-01-01

07.11.14 KB. Emailed author re copyright. Author says that copyright is retained by author. Ok to add to spiral Automated face recognition and identi cation softwares are becoming part of our daily life; it nds its abode not only with Facebooks auto photo tagging, Apples iPhoto, Googles Picasa, Microsofts Kinect, but also in Homeland Security Departments dedicated biometric face detection systems. Most of these automatic face identification systems fail where the e ects of aging come into...

I'm OK, You're (Not) OK: Teaching in a World of Relativism.

Science.gov (United States)

Ryder, Phyllis Mentzell

1995-01-01

Examines three techniques to overcome relativism: (1) a hierarchical view, in which the socially constructed view is superior; (2) a belief that a true understanding of personal experience will lead to political awareness; and (3) an assertion that the socially constructed view is more ethical than other views. Argues that first two approaches are…

Turning a Private Story into a Public Event. Frame Analysis of Scandals in Television Performance

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Olga Galanova

2012-07-01

Full Text Available It does not suffice to treat scandals only as supra-individual discourses on the macro level of  social communication. Rather we have to develop concrete methodical principles for the description of the practice of doing scandal in certain media. In this paper we look at these practices from a micro-sociological perspective and analyze how and through which concrete actions an event is staged as a scandal. Practices of scandal build a special frame of media communication, which allows  television producers to solve certain "communicative problems." Based on the detailed analysis of a video recording of a television show we exemplify how a private case turns to a public event by means of  scandal-framing. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs120398

Review Essay: Our Rules Leave a Backdoor Open—At the Heart of the Radically Incomplete Psychoanalytic Process

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Michael Langenbach

2008-10-01

Full Text Available Practical work in psychoanalytic practice is a core component of the enhancement of psychoanalytic knowledge. Despite its importance it is a rather dark chapter in the research history of psychoanalysis and empirical research into what actually happens in practice has been rare. The book by Andreas STRATKÖTTER reviewed here takes psychoanalytic practice as the empirical basis of an extensive qualitative study. The psychoanalysts interviewed by STRATKÖTTER describe the criteria they take to indicate the need for psychoanalytic treatment, the practical relevance of central psychoanalytic notions, and their professional development after psychoanalytic training. STRATKÖTTER's study can be taken as a reference for demands for improvements in the culture of psychoanalytic training and for further development of qualitative research approaches in psychoanalysis. URN: urn:nbn:de:0114-fqs0901173

Dolmetscher/inneneinsatz in der qualitativen Sozialforschung. Zu Anforderungen und Auswirkungen in gedolmetschten Interviews

Directory of Open Access Journals (Sweden)

Gwendolin Lauterbach

2014-03-01

Full Text Available Der Einsatz von Dolmetscher/innen in der qualitativen Sozialforschung, insbesondere in qualitativen Interviews, stand bisher nicht im Mittelpunkt der Forschung, stellt jedoch die Interviewteilnehmer/innen vor Herausforderungen. Diese betreffen v.a. den Umgang mit dem Dolmetscher/der Dolmetscherin und deren Rolle sowie die Interviewauswertung und die Qualität der Daten und folgenden wissenschaftlichen Erkenntnisse. Aus der bisherigen Diskussion lassen sich nur bedingt methodische Leitlinien aus anderen, verwandten Bereichen ableiten. Anhand von Expert/inneninterviews mit Forscher/innen und Dolmetscher/innen werden daher Erfahrungen mit dem Dolmetscher/inneneinsatz in der qualitativen Sozialforschung dokumentiert und Handlungsempfehlungen abgeleitet. Mithilfe von Gesprächsaufzeichnungen gedolmetschter Interviews werden die Aushandlungen zwischen Originalen und Dolmetschungen aufgezeigt sowie Auswirkungen des Dolmetscher/inneneinsatzes auf den Interviewprozess dargelegt. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs140250

Tagungsbericht: Wissenssoziologische Diskursanalyse & angrenzende Perspektiven der Diskursforschung

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Cindy Ballaschk

2015-07-01

Full Text Available Der vorliegende Beitrag gibt einen Einblick in Ablauf und Themen der Augsburger Spring School 2015 "Wissenssoziologische Diskursanalyse & angrenzende Perspektiven der Diskursforschung". An drei Tagen beschäftigten sich 30 Teilnehmer_innen intensiv mit drei verschiedenen Ansätzen aus dem Forschungsprogramm der wissenssoziologischen Diskursanalyse. Dieser Tagungsbericht gibt einen Überblick über diskutierte Fragestellungen sowie über Inhalte der Vorträge und Workshops. Angeboten wurden Workshops zur wissenssoziologischen Diskursanalyse von Reiner KELLER, zur Dispositivanalyse von Werner SCHNEIDER und zur Narrationsanalyse von Willy VIEHÖVER. Mithilfe von zahlreichen Beispielen sowie durch die konkrete Arbeit am Material wurde den Teilnehmenden die Möglichkeit gegeben, die Spezifik der jeweiligen Methodologie kennenzulernen und ihre Stärken und Grenzen auszuloten. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1503225

Visão panorâmica das pesquisas sobre texto no Brasil Visão panorâmica das pesquisas sobre texto no Brasil

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Ingedore G. Villaça Koch

2008-04-01

Full Text Available 0 despertar do interesse, no Brasil, pela abordagem lingilistica do texto - literario ou nio-literario - data do final da decada de 70. Para tanto, contribuiu, de forma significativa, a traducao para o portugues de duas obras sobre o assunto: SemiOtica narrativa e textual (Chabrol et al. 1977, coletanea de trabalhos mais voltados para o escudo da narrativa, entre os quais se podem citar urn do prOprio Chabrol "Alguns problemas de gramatica narrativa e textual" e outro de van Dijk "Gramaticas textuais e estruturas narrativas", este corn urn item sobre Textual (ainda bastante calcado na Gramatica Gerativa e na Semantica LOgica; e LingUtstica e teoria de texto (Schmidt 1978, em que se desenvolve a teoria dos "jogos de atuacio comunicativa", numa perspectiva predominantemente psicossocial.

Review Essay: The Dialectic of the General and Particular in Social Science Research and Teaching Praxis

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Wolff-Michael Roth

2003-05-01

Full Text Available Cross-Cultural Research Methods pretends to be a primer on the "how to" of conducting cross-cultural research, but focuses only on quantitative methods that use secondary data in the service of generating knowledge. The book is caught twice in the dialectic of the general and the specific, by putting all its eggs into the former basket and failing to recognize the role of the latter both in research itself and in the teaching of research methods to its readers. Because I know that the students in my graduate research methods course would fail to appreciate the book, I would neither select nor recommend it to others as a resource in teaching (quantitative research methods or research designs courses. URN: urn:nbn:de:0114-fqs030268

Social Constructionist Psychology and its Application. Possibilities for a Reorientation

Directory of Open Access Journals (Sweden)

Johannes von Tiling

2008-01-01

Full Text Available Social constructionism currently is understood as a metatheoretical alternative to positivism. It serves many social and cultural scientists as a point of reference. The possibilities to understand it as a psychological program of research that leaves space for agency and subjectivity usually are neglected. Promoting a dialogue with mainstream psychology constitutes one way of fostering social constructionist psychology. In addition, a theoretically productive conception of social constructionist psychology cannot do without reference to cultural psychology. An important advantage of such a conception lies in the increased number of possibilities for practical applications in hospitals, schools and factories. Whereas present applications of social constructionism tend to promote the postmodernization and individualization of the client, applied social constructionist psychology avoids these concomitant effects. URN: urn:nbn:de:0114-fqs0801446

Review Essay: "Personal Relations" as a Sociological Category?

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Rainer Schützeichel

2010-08-01

Full Text Available This review essay discusses the question raised by the handbook "Personal Relations": whether and to what extent personal relations can be understood as a fundamental sociological category, one that is uniform and covers social relations such as pair relationships, brother-sister and parent-child relationships, family relations, friendships, neighbourhoods or informal working groups. It examines the different criteria which—according to the publishers—plead for establishing personal relations as a joint structural form. However, it also considers further aspects, such as the ways in which these forms of personal relations differ from other social relations, and raises the question of whether these differences can only be reconstructed through the means of an a-historical, systematic comparison of social relations—as suggested by the handbook. URN: urn:nbn:de:0114-fqs1003187

Two Reflexivities in Current Social Science: Remarks on an Absent Debate

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Andreas Langenohl

2009-02-01

Full Text Available This paper traces and compares two different uses of the category of reflexivity in contemporary methodological debates in the social sciences. While a first use is strongly influenced by the textual turn in cultural anthropology, a second use is aligned with Pierre BOURDIEU's notion of "scientific reflexivity." Whereas the first use postulates an epistemological break with scientific modernity and argues for a perpetual contextualization and interrelation of research results and methods, BOURDIEU defends sociology’s claim of objectivity, which, according to him, can be redeemed through a reflexive objectification of sociological practice. Up to the present these two uses have existed in almost complete isolation from each other. They represent alternating reactions to, and reconstructions and translations of, poststructuralism and postmodernism in the social sciences. URN: urn:nbn:de:0114-fqs090297

On the Problem of Validity of Qualitative Research

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Jo Reichertz

2000-06-01

Full Text Available Whether the research results put forth by (social scientists on behalf of their professional vocation and on behalf of their professional standards they adhere to, can be regarded as valid, shall be examined from the perspective of the sociology of knowledge. By means of applying the sociology of knowledge to its own research results, it shall be shown that research and research results are inevitably bound to perspective (in fact, not a surprising insight. Therefore—so the underlying thesis of the argument—, research must be aimed at the systematic production of doubt in order to facilitate maximum extinction of fault. Suggestions are advanced of how qualitative research projects can be defended despite the increasing competition regarding research grants and despite the problematic epistemological position. URN: urn:nbn:de:0114-fqs0002324

Review: Ingrid Miethe, Claudia Kajatin & Jana Pohl (Eds. (2004. Geschlechterkonstruktionen in Ost und West. Biografische Perspektiven [Gender Constructions in East and West. Biographical Perspectives

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Nicola Döring

2006-03-01

Full Text Available This reader contains analyses of gender constructions in East and West Germany from biographical perspectives. It is based on narrative interviews with women and men living in the former East and West. By means of case reconstructions and case comparisons the authors reveal how individuals deal actively with specific societal gender roles. Historical differences between women's movement and feminism in East Germany versus West Germany are knowledgeably described. The book offers a very complex and multilayered theoretical and empirical construction of gender in its diverse dimensions, but men's biographies and men's studies remain marginalized. Men's movements as well as the gay rights movement are blind spots. The gendering of work and the context of European unification are emphasized. URN: urn:nbn:de:0114-fqs0602353

Review: David Silverman (2006. Interpreting Qualitative Data: Methods for Analysing Talk, Text and Interaction

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Paul Ten Have

2008-01-01

Full Text Available This edition of SILVERMAN's well-known book offers a wide-ranging introduction to the problems facing any qualitative researcher, especially as concerns the design of qualitative projects and the analysis of qualitative data. It is in many ways a personal book, often referring to the author's own experience and reflecting his own intellectual development. He is clear about his preferences and doubts, but offers good arguments for both. While it is presented as a textbook for undergraduates, it may be considered too demanding intellectually in some cases. The review offers an extensive overview of the book's contents, in order to facilitate a teacher's choice of it as a course book, but it is recommended without reservation to any serious qualitative researcher. URN: urn:nbn:de:0114-fqs0801160

Review Essay: Grenzgänger Seeks Reflexive Methodology

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Wolff-Michael Roth

2002-09-01

Full Text Available Reflexive Methodology reviews major strands of current thought in epistemology, philosophy, social science, and interpretive methods. The book falls short in that it neither does a thorough job reviewing the literature nor does it provide method-related advice useful to students. Grenzgängerin constitutes a collection of essays on a broad range of topics, but which are only loosely connected if at all. Drawing on DERRIDA and the notion of a historical science of the historical subject, I attempt to practice method, something I missed in both texts. I make explicit the historical nature of my own writing and the historical nature of my subject. I make explicit intertextuality and in the process practice reflexivity in the particular way I am writing. URN: urn:nbn:de:0114-fqs020328

Dialogue and Power in Parent-Child Communication

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Megan K. Foley

2006-03-01

Full Text Available Michelle MILLER-DAY (2004 provides an in-depth account of the negotiation of power in intergenerational maternal relationships. She provides a useful alternative to socialization and compliance-gaining perspectives on social influence between parents and children, which have limited formulations of children's agency. She proposes that despite their different statuses in the family hierarchy, both mothers and daughters experience a dialectical tension between power and powerlessness in communicative transactions. MILLER-DAY develops a grounded theory of necessary convergence, a symbolic process in which daughters—both powerfully and powerlessly—adopt their mothers' interpretations in order to maintain their relationship. This theory of necessary convergence can be productively supplemented by theorizations of dialogic multivocality, enabling this work's potentially broad transferability. URN: urn:nbn:de:0114-fqs0602120

Conference Report: 18th Conference on Computer-Assisted Qualitative Data Analysis (CAQD 2016: MAXQDA User Conference

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Carlos Galan-Diaz

2017-01-01

Full Text Available During the first week of March 2016, 120 researchers from 12 different countries, including Syria, Japan, the USA and Turkey, met in Berlin (Germany to learn more about their computer-assisted qualitative data analysis skills. The 18th Conference on Computer-Assisted Qualitative Data Analysis (CAQD offered several workshops, a research methods poster session, and the opportunity to share and discuss best practice between attendees, trainers and speakers (informally and through the user forum. The conference also hosted three seminal keynote speakers in two presentations: John CRESWELL, and Udo KUCKARTZ and Stefan RÄDIKER, who shared, respectively, the state of the art of mixed methods and the ways that software can support these approaches. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs170146

Review Essay: "If Somebody's with Something Every Day They've Gotta Learn Something—Or They're Just Out to Lunch": The Dialectics of Ethnography as a Way of Being

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Wolff-Michael Roth

2003-09-01

Full Text Available Ethnography: A Way of Seeing addresses itself to students in anthropology and researchers in other professional fields, intending to help them in understanding what is distinctive about ethnography as a discipline rather than merely being another fieldwork technique. Although I contest the claim to the particular audience—experienced researchers will much more appreciate the different points Harry Wolcott makes—I found this a highly enjoyable book, the textual nature of which I attempted to reflexively capture in this review. Drawing on my own fieldwork in a fish hatchery as an interpretive horizon and on the techniques of ethnographic writing, I articulate a dialectical framework that allows readers to situate a number of contradictions that have become salient during my reading. URN: urn:nbn:de:0114-fqs0303142

Review: Aglaja Przyborski & Monika Wohlrab-Sahr (2009. Qualitative Sozialforschung. Ein Arbeitsbuch [Qualitative Research. A Textbook

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Oliver Berli

2010-08-01

Full Text Available The introductory textbook "Qualitative Sozialforschung [Qualitative Research]" by PRZYBORSKI and WOHLRAB-SAHR is addressed to students and teachers alike interested in methodology and methods. The authors aim to describe the research process as a whole in all its elements. The volume therefore includes comprehensive chapters concerning methodology, sampling procedures and displaying of results, as well as chapters dealing with special forms of generating and analyzing data (e.g. grounded theory. The authors compare the approaches presented and work out their similarities rather than differences. Although this textbook offers a sound introduction to qualitative research, in stressing similarities the authors tend to neglect important methodological differences. The chapter dealing with criteria for evaluating the quality of research is one such example of this tendency. URN: urn:nbn:de:0114-fqs100325

Review: Barbara Merril & Linden West (2009. Using Biographical Methods in Social Research

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Vanessa Garcia Diaz

2011-11-01

Full Text Available The return of the subject in the social sciences reflects growing interest in the study of subjectivity. This refers to opportunities for individuals to make meaning of their lives within the institutions of society. MERRIL and WEST’s text serves as a reference for using biographical methods, as well as a reflection on the methodological and ethical issues inherent in doing this type of research.  This review examines the relationship between the book's content and its formal characteristics (didactic style, writing style and its interdisciplinary nature. This review also focuses on the advantages that this textbook may offer if used in  qualitative research courses in general and, specifically, in courses dealing with biographical research methods. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1201104

Computer-Aided Qualitative Data Analysis with Word

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Bruno Nideröst

2002-05-01

Full Text Available Despite some fragmentary references in the literature about qualitative methods, it is fairly unknown that Word can be successfully used for computer-aided Qualitative Data Analyses (QDA. Based on several Word standard operations, elementary QDA functions such as sorting data, code-and-retrieve and frequency counts can be realized. Word is particularly interesting for those users who wish to have first experiences with computer-aided analysis before investing time and money in a specialized QDA Program. The well-known standard software could also be an option for those qualitative researchers who usually work with word processing but have certain reservations towards computer-aided analysis. The following article deals with the most important requirements and options of Word for computer-aided QDA. URN: urn:nbn:de:0114-fqs0202225

Metaphor Analysis and the Construction of Gender

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Rudolf Schmitt

2009-02-01

Full Text Available Recently there has been an increasing number of studies on the construction of gender based on metaphors (KOLLER, 2004a, 2004b, 2005; ANDERSON VASBY & HORN SHEELER, 2005; EBELING & SCHMITZ, 2006; BOCK VON WÜLFINGEN, 2007. Many of these studies seem to have overlooked one of the most thoroughly developed theories of metaphor, LAKOFF and JOHNSON's so-called cognitive theory of metaphor or limited themselves to LAKOFF and JOHNSON's first book from 1980. In this article I explore current research on metaphor and gender and sketch the central topics of the cognitive theory of metaphor and develop a revision of this theory. It is hoped that this will enhance further research in metaphor analysis concerning the construction of gender. URN: urn:nbn:de:0114-fqs0902167

Integrating the Self and the Spirit: Strategies for Aligning Qualitative Research Teaching with Indigenous Methods, Methodologies, and Epistemology

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Sarah K. Knudson

2015-07-01

Full Text Available Many universities internationally now make concerted efforts to promote curriculum development and classroom and campus cultures that recognize diversity in student viewpoints and life experiences. Increasingly, these efforts have involved promoting recognition and inclusion of indigenous knowledges in the university setting. If adopted in the classroom, the promotion of indigenous perspectives suggests exciting possibilities for teaching qualitative research critically. Existing educational resources, however, offer little guidance on achieving this through undergraduate qualitative methods teaching. Using examples of Canadian undergraduate teaching initiatives, I suggest that by integrating indigenous methods, perspectives, and epistemology, particularly through student opportunities for community-engaged learning and exposure to participatory action research, teaching qualitative research can promote critical recognition of multiple ways of knowing. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs150347

Blood and Books: Performing Code Switching

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Jeff Friedman

2008-05-01

Full Text Available Code switching is a linguistic term that identifies ways individuals use communication modes and registers to negotiate difference in social relations. This essay suggests that arts-based inquiry, in the form of choreography and performance, provides a suitable and efficacious location within which both verbal and nonverbal channels of code switching can be investigated. Blood and Books, a case study of dance choreography within the context of post-colonial Maori performance in Aotearoa/New Zealand, is described and analyzed for its performance of code switching. The essay is framed by a discussion of how arts-based research within tertiary higher education requires careful negotiation in the form of code switching, as performed by the author's reflexive use of vernacular and formal registers in the essay. URN: urn:nbn:de:0114-fqs0802462

75 FR 58426 - Notice of Intent to Repatriate Cultural Items: Thomas Gilcrease Institute of American History and...

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2010-09-24

...: Thomas Gilcrease Institute of American History and Art, Tulsa, OK AGENCY: National Park Service, Interior... Thomas Gilcrease Institute of American History and Art (Gilcrease Museum), Tulsa, OK, that meet the... the Gilcrease Museum for the preservation of North American history. The first bundle is made of...

Veneetsia pärgab sotsiaalkriitikuid / Johannes Saar

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Saar, Johannes, 1965-

2005-01-01

13. juunil avatud Veneetsia 51. kunstibiennaalist. Rahvuspaviljonidest, preemiasaajaid. Elutööpreemia sai Barbara Kruger, kuraatoripreemiad Rosa Martinez ja Maria de Corral. Eestit esindab Mark Raidpere, kuraator Hanno Soans. Kesk-Aasia paviljonist lisas "Tapetud vaikitakse maha". Usbeki, Kirgiisi ja Kasahstani kunstnike ühisnäituse kuraator on Viktor Misiano Moskvast

Speaking the Same Language: Building a Data Governance Program for Institutional Impact

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Chapple, Mike

2013-01-01

Colleges and universities should be among the world's leading institutions in the field of data governance. After all, higher education institutions are dedicated to the creation and dissemination of knowledge. Why, then, do those who work in colleges and universities often have so much difficulty corralling information about their own operations…

Dětské žárové hroby na pohřebišti lužické kultury v Opavě-Kateřinkách

Czech Academy of Sciences Publication Activity Database

Juchelka, Jiří

2007-01-01

Roč. 42, - (2007), s. 99-112 ISSN 0560-2793 Institutional research plan: CEZ:AV0Z80010507 Keywords : Lusatian culture * burial ground * urn graves * Czech Silesia * Upper Silesia Subject RIV: AC - Archeology, Anthropology, Ethnology

Estimating the spatial distribution of soil moisture based on Bayesian maximum entropy method with auxiliary data from remote sensing

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Gao, Shengguo; Zhu, Zhongli; Liu, Shaomin; Jin, Rui; Yang, Guangchao; Tan, Lei

2014-10-01

Soil moisture (SM) plays a fundamental role in the land-atmosphere exchange process. Spatial estimation based on multi in situ (network) data is a critical way to understand the spatial structure and variation of land surface soil moisture. Theoretically, integrating densely sampled auxiliary data spatially correlated with soil moisture into the procedure of spatial estimation can improve its accuracy. In this study, we present a novel approach to estimate the spatial pattern of soil moisture by using the BME method based on wireless sensor network data and auxiliary information from ASTER (Terra) land surface temperature measurements. For comparison, three traditional geostatistic methods were also applied: ordinary kriging (OK), which used the wireless sensor network data only, regression kriging (RK) and ordinary co-kriging (Co-OK) which both integrated the ASTER land surface temperature as a covariate. In Co-OK, LST was linearly contained in the estimator, in RK, estimator is expressed as the sum of the regression estimate and the kriged estimate of the spatially correlated residual, but in BME, the ASTER land surface temperature was first retrieved as soil moisture based on the linear regression, then, the t-distributed prediction interval (PI) of soil moisture was estimated and used as soft data in probability form. The results indicate that all three methods provide reasonable estimations. Co-OK, RK and BME can provide a more accurate spatial estimation by integrating the auxiliary information Compared to OK. RK and BME shows more obvious improvement compared to Co-OK, and even BME can perform slightly better than RK. The inherent issue of spatial estimation (overestimation in the range of low values and underestimation in the range of high values) can also be further improved in both RK and BME. We can conclude that integrating auxiliary data into spatial estimation can indeed improve the accuracy, BME and RK take better advantage of the auxiliary

76 FR 18547 - Grand River Dam Authority, Salina Pumped Storage Project; Notice of Proposed Restricted Service...

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2011-04-04

... Practice and Procedure, 18 CFR 385.2010, provides that, to eliminate unnecessary expense or improve... all individual undertakings carried out in accordance with the license until the license expires or is... Nazih Zuhdi Muscogee (Creek) Nation, P.O. Drive, Oklahoma, OK 73105-7917. Box 580, Okmulgee, OK 74447...

Cyberspace and Real-World Behavioral Relationships: Towards the Applications of Interest Search Queries to Identify Individuals At-Risk for Suicide

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2012-06-14

optima ducati cva 308 dealers Topic 30: 11 101 24 23 13 boat afman vol 110 21 Topic 31: travel government citi camp writing apa az 5k essay ...password connect reset ip corral monitor Topic 67: lyrics amazon mac michelle want jesus highest hate congress cast Topic 68: 2009 block southern

Manipulation of the surface density of states of Ag(111) by means of resonators: Experiment and theory

Czech Academy of Sciences Publication Activity Database

Fernández, J.; Moro-Lagares, María; Serrate, D.; Aligia, A.A.

2016-01-01

Roč. 94, č. 7 (2016), s. 1-8, č. článku 075408. ISSN 2469-9950 Institutional support: RVO:68378271 Keywords : scanning tunneling spectroscopy * quantum corrals * mirages Subject RIV: BM - Solid Matter Physics ; Magnetism OBOR OECD: Condensed matter physics (including formerly solid state physics, supercond.) Impact factor: 3.836, year: 2016

State plans to corral city officials / Ella Karapetyan

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Karapetyan, Ella

2010-01-01

Kui Tallinn võtab 2010. aastal 357 miljonit krooni laenu, mis võib takistada euroga liitumist, kavatseb riik maksmata jätta osa tulumaksust. Majandus- ja kommunikatsiooniminister Juhan Partsi ja rahandusminister Jürgen Ligi arvamused

Review: Karin Reiber (2005. Organisation im Spiegel der Regula Benedicti [Organisation in Reflection of Regula Benedicti

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Jürgen Rausch

2007-01-01

Full Text Available For 1500 years, the monastic life of the Benedictines has been defined by rules dating from the time of the first foundation of the order, suggesting an organizational structure that has outlasted historical upheavals and changes. Starting from a new understanding of organisational development as organisational learning, Karin REIBER has looked for clues to organisational formation and learning through a hermeneutic textual analysis of the Regula Benedicti of the 6th Century. Within a theoretical framework, REIBER develops three dimensions of organisational formation and three stages of organisational learning. In a historical reconstruction, the author analyses the text of the Regula Benedicti. In a second section, REIBER adapts and interprets the results of the hermeneutic analysis through a double three-stage theoretical model. She works out interesting aspects for organisational learning, which relate individual learning to organisational learning in favour of members of the organisation, for which consideration for individuality forms a part of the leadership concept and as a framework for social relationships, establishing an informal organisational structure beside the formal one. This illuminating work leads to an integrated concept of organisational learning, which extends the notion of tradition as a characteristic feature of an innovative organisation and which, through continuity and topicality, can hence guarantee the continued existence of modern organisations in the future. URN: urn:nbn:de:0114-fqs070174

Legitimate Peripheral Participation as a Framework for Conversation Analytic Work in Second Language Learning

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Gitte Rasmussen Hougaard

2009-03-01

Full Text Available Since its inception, Conversation Analysis (CA has become not only a framework and a set of methods for studying the generic machinery of talk-in-interaction but also a celebrated, qualitative method for studying a wealth of phenomena and exploring and testing concepts and hypotheses from numerous disciplines, including linguistics, psychology, anthropology and Second Language Acquisition (SLA. CA is often resorted to as the key to resolving knots and dead-ends in these neighboring disciplines. Despite the very interesting results that such work admittedly produces, it is too often not accompanied by focused considerations of how the specific concerns from one field match with the aims that CA procedures have been developed for and hence with the procedures themselves. This paper takes recent applications of CA to the study of SLA as a case in point. It discusses a whether CA can shed light on "learning" as commonly defined in SLA and b whether the resort to a particular model of learning (LAVE & WENGER, 1991, Legitimate Peripheral Participation (LPP helps overcoming some of the problems with which CA work in SLA is confronted. It is hoped that the specific discussions of problems involved in the project, CA-for-SLA, will contribute to the ongoing, general discussion of qualitative research methods and their prospects and problems. URN: urn:nbn:de:0114-fqs090247

Balance disorder and increased risk of falls in osteoporosis and kyphosis: significance of kyphotic posture and muscle strength.

Science.gov (United States)

Sinaki, Mehrsheed; Brey, Robert H; Hughes, Christine A; Larson, Dirk R; Kaufman, Kenton R

2005-08-01

This controlled trial was designed to investigate the influence of osteoporosis-related kyphosis (O-K) on falls. Twelve community-dwelling women with O-K (Cobb angle, 50-65 degrees measured from spine radiographs) and 13 healthy women serving as controls were enrolled. Mean age of the O-K group was 76 years (+/-5.1), height 158 cm (+/-5), and weight 61 kg (+/-7.9), and mean age of the control group was 71 years (+/-4.6), height 161 cm (+/-3.8), and weight 66 kg (+/-11.7). Quantitative isometric strength data were collected. Gait was monitored during unobstructed level walking and during stepping over an obstacle of four different heights randomly assigned (2.5%, 5%, 10%, and 15% of the subject's height). Balance was objectively assessed with computerized dynamic posturography consisting of the sensory organization test. Back extensor strength, grip strength, and all lower extremity muscle groups were significantly weaker in the O-K group than the control group (P controls for all conditions of unobstructed and obstructed level walking. Obstacle height had a significant effect on all center-of-mass variables. The O-K subjects had significantly greater balance abnormalities on computerized dynamic posturography than the control group (P =0.002). Data show that thoracic hyperkyphosis on a background of reduced muscle strength plays an important role in increasing body sway, gait unsteadiness, and risk of falls in osteoporosis.

Combination therapy of radiation and immunomodulators in the treatment of MM46 tumor transplanted in C3H/He mice

Energy Technology Data Exchange (ETDEWEB)

Miyaji, C.; Ogawa, Y.; Imajo, Y.; Kimura, S. (Kobe Univ. (Japan). School of Medicine)

1982-06-01

Female C3H/He mice aged 12 weeks, transplanted MM46 tumor, were used in this study on the timing of administration of immunomodulators, such as PSK (a proteinbound polysaccharide prepared from Coriolus versicolor), OK-432 (Streptococcal preparation), bestatin (inhibitor of aminopeptidases of microbial origin) and levamisole (a chemical substance belonging to anthelmintics) combined with two fractionated local irradiation with the total dose of 3,000 rads. The daily dose of 250 ng/kg of PSK, 1 KE/mouse of OK-432, 300 mu g/mouse of bestatin or 3mg/kg of levamisole was respectively injected intraperitoneally for four consecutive days before or after irradiation. The anti-tumor effect was evaluated by the changes of tumor volume and survival curves. When PSK, OK-432 or levamisole was administered after irradiation, tumor growth was decreased and sixty-day survival rate and survival curve were significantly elongated compared with the control group and the group to which PSK, OK-432 or levamisole administered before irradiation (p lt 0.01). As for bestatin, no remarkable difference was observed irrespective of the timing of administration. These results suggested that some immunomodulators showed different anti-tumor activity depending on its timing of administration in the combination with radiotherapy. Concerning PSK, OK-432 and levamisole, they seemed to be beneficial in combination with prior radiotherapy in the treatment of MM46 tumor.

Combination therapy of radiation and immunomodulators in the treatment of MM46 tumor transplanted in C3H/He mice

International Nuclear Information System (INIS)

Miyaji, Chihiro; Ogawa, Yasuhiro; Imajo, Yoshinari; Kimura, Shuji

1982-01-01

Female C3H/He mice aged 12 weeks, transplanted MM46 tumor, were used in this study on the timing of administration of immunomodulators, such as PSK (a proteinbound polysaccharide prepared from Coriolus versicolor), OK-432 (Streptococcal preparation), bestatin (inhibitor of aminopeptidases of microbial origin) and levamisole (a chemical substance belonging to anthelmintics) combined with two fractionated local irradiation with the total dose of 3,000 rads. The daily dose of 250 ng/kg of PSK, 1 KE/mouse of OK-432, 300 mu g/mouse of bestatin or 3mg/kg of levamisole was respectively injected intraperitoneally for four consecutive days before or after irradiation. The anti-tumor effect was evaluated by the changes of tumor volume and survival curves. When PSK, OK-432 or levamisole was administered after irradiation, tumor growth was decreased and sixty-day survival rate and survival curve were significantly elongated compared with the control group and the group to which PSK, OK-432 or levamisole administered before irradiation (p lt 0.01). As for bestatin, no remarkable difference was observed irrespective of the timing of administration. These results suggested that some immunomodulators showed different anti-tumor activity depending on its timing of administration in the combination with radiotherapy. Concerning PSK, OK-432 and levamisole, they seemed to be beneficial in combination with prior radiotherapy in the treatment of MM46 tumor. (author)

Çokşeritli Dönel Kavşaklarda Kapasite Analizi: Highway Capacity Manual 2010 Kapasite Modeliyle Bir Değerlendirme

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Melike Ersoy

2014-06-01

Full Text Available Bu çalışmada, genel kabul görmüş çok şeritli dönel kavşak kapasite hesap yöntemlerinin uygulanabilirliği, yeni Highway Capacity Manual (HCM 2010 yöntemiyle karşılaştırılmıştır. Yöntemlerden elde edilen sonuçlar, yerel çalışmalardan toplanan verilerin ışığında değerlendirilmiştir. Karşılaştırma için regresyon analiz yöntemini temsilen Transportation Research Laboratory (TRL formülasyonu, Kritik aralık kabulü yöntemini temsilen Avusturya Hesap Yöntemi seçilmiştir. Bunlara ek olarak, sınırlı öncelik ve ters öncelik koşullarının göz önünde bulundurulduğu kalibre edilmiş kritik aralık yöntemi ve HCM 2010 da yerel uygulamalar için öngörülen kalibre edilmiş formüller ile hesaplamalar yapılmış ve HCM 2010'un olağan değerleriyle karşılaştırılmıştır.Çalışmanın sonucunda elde edilenler, kritik aralık kabul yöntemi ve regresyon yönteminin HCM 2010 olağan değerlerine kıyasla genellikle daha yüksek sonuçlar verdiğini göstermiştir. Yöntemler arasında yapılan regresyon analizleri sonucu, özellikle yüksek dönen akımlar altında kritik aralık kabul yönteminin HCM 2010 yönteminden daha uygun sonuçlar verdiği görülmüştür. Ancak HCM 2010'da yerel uygulamalar için kalibrasyon yapılmasını sağlayan formülasyon sonucunda elde edilenler, olağan formülasyonun verdiği düşük kapasite tahminlerini daha uygun değerlere yükseltmiştir.

State-Space Inference and Learning with Gaussian Processes

OpenAIRE

Turner, R; Deisenroth, MP; Rasmussen, CE

2010-01-01

18.10.13 KB. Ok to add author version to spiral, authors hold copyright. State-space inference and learning with Gaussian processes (GPs) is an unsolved problem. We propose a new, general methodology for inference and learning in nonlinear state-space models that are described probabilistically by non-parametric GP models. We apply the expectation maximization algorithm to iterate between inference in the latent state-space and learning the parameters of the underlying GP dynamics model. C...

TAŞIT DİNAMİĞİ UYGULAMALARINDA KULLANILAN LASTİK TEKERLEK MODELLERİ VE TAŞIT KAZA SİMULASYONLARINDA KULLANILMALARI

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Osman ELDOĞAN

1995-01-01

Full Text Available Taşıt ile yol arası ilişki lastik tekerlek ile olduğu için tekerlek modeli, taşıt modellemelerinde çok büyük öneme sahiptir. Taşıt modelleri, taşıt tasarımında kullanılan dinamik modeller olabileceği gibi kaza simulasyonlarında kullanılan modeller de olabilir. Bu önemi dolayısıyla tekerlek modellemesi üzerine çok sayıda çalışma yapılmış olup, bu modellemelerde teorik, deneysel ve bu ikisi arası değişik kombinasyonlar kullanılmıştır. Bu çalışmada tekerlek modellerinin gelişimi ve yapılan çalışmalar hakkında bilgi verilmiş ve bunların trafik kaza simulasyonlarında kullanılmaları hakkında bir değerlendirme yapılmıştır.

Future Dead

DEFF Research Database (Denmark)

Sabra, Jakob Borrits

Today the dying and the bereaved attend memorialization both online and offline. Cemeteries, urns, coffins, graves, memorials, monuments, websites, social network sites, applications and software services, form technologies that are influenced by discourse, culture, public, professional and econo...

Economic Intervention and Parenting: A Randomized Experiment of Statewide Child Development Accounts

Science.gov (United States)

Nam, Yunju; Wikoff, Nora; Sherraden, Michael

2016-01-01

Objective: We examine the effects of Child Development Accounts (CDAs) on parenting stress and practices. Methods: We use data from the SEED for Oklahoma Kids (SEED OK) experiment. SEED OK selected caregivers of infants from Oklahoma birth certificates using a probability sampling method, randomly assigned caregivers to the treatment (n = 1,132)…

Interevent time distribution in seismicity: A theoretical approach

International Nuclear Information System (INIS)

Molchan, G.

2004-09-01

This paper presents an analysis of the distribution of the time τ between two consecutive events in a stationary point process. The study is motivated by the discovery of unified scaling laws for τ for the case of seismic events. We demonstrate that these laws cannot exist simultaneously in a seismogenic area. Under very natural assumptions we show that if, after resealing to ensure Eτ = 1, the interevent time has a universal distribution F, then F must be exponential. In other words, Corral's unified scaling law cannot exist in the whole range of time. In the framework of a general cluster model we discuss the parameterization of an empirical unified law and the physical meaning of the parameters involved

Captive chimpanzee (Pan troglodytes) behavior as a function of space per animal and enclosure type.

Science.gov (United States)

Neal Webb, Sarah J; Hau, Jann; Schapiro, Steven J

2018-03-01

Space per animal, or animal density, and enclosure type are important elements of functionally appropriate captive environments (FACEs) for chimpanzees. The National Institutes of Health (NIH) recommends that captive chimpanzees be maintained in areas of >250 ft 2 /animal. Several studies have investigated chimpanzee behavior in relation to space per animal, but only two studies have examined these variables while attempting to hold environmental complexity constant. Both have found few, if any, significant differences in behavior associated with increased space per animal. The NIH does not provide recommendations pertaining to enclosure type. Although Primadomes™ and corrals are considered acceptable FACE housing, no studies have investigated chimpanzee behavior in relation to these two common types of enclosures. We examined the NIH space per animal recommendation, and the effects of enclosure type, while maintaining similar levels of environmental complexity. We used focal animal observations to record the behavior of 22 chimpanzees in three social groups following within-facility housing transfers. Chimpanzees that were moved from an area with space below the NIH recommendation to the same type of enclosure with space above the recommendation (dome to double dome) exhibited significantly more locomotion and behavioral diversity post-transfer. Chimpanzees that were moved from an area with space below the recommendation to a different type of enclosure with space above the recommendation (dome to corral) exhibited significant increases in foraging and behavioral diversity, and a decrease in rough scratching. Lastly, chimpanzees that were moved from an area above the recommendation to a different enclosure type with space equal to the recommendation (corral to double dome) exhibited an increase in behavioral diversity. These results add to the body of literature that addresses the concept of specific minimum space requirements per chimpanzee, and highlight the

Observing Participating Observation—A Re-description Based on Systems Theory

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Tina Bering Keiding

2010-09-01

Full Text Available Current methodology concerning participating observation in general leaves the act of observation unobserved. Approaching participating observation from systems theory offers fundamental new insights into the topic. Observation is always participation. There is no way to escape becoming a participant and, as such, co-producer of the observed phenomenon. There is no such thing as a neutral or objective description. As observation deals with differences and process meaning, all descriptions are re-constructions and interpretations of the observed. Hence, the idea of neutral descriptions as well as the idea of the naïve observer becomes a void. Not recognizing and observing oneself as observer and co-producer of empirical data simply leaves the process of observation as the major unobserved absorber of contingency in data production based on participating observation. URN: urn:nbn:de:0114-fqs1003119

Transparency in Transcribing: Making Visible Theoretical Bases Impacting Knowledge Construction from Open-Ended Interview Records

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Audra Skukauskaite

2012-01-01

Full Text Available This article presents a reflexive analysis of two transcripts of an open-ended interview and argues for transparency in transcribing processes and outcomes. By analyzing ways in which a researcher's theories become consequential in producing and using transcripts of an open-ended interview, this paper makes visible the importance of examining and presenting theoretical bases of transcribing decisions. While scholars across disciplines have argued that transcribing is a theoretically laden process (GREEN, FRANQUIZ & DIXON, 1997; KVALE & BRINKMAN, 2009, few have engaged in reflexive analyses of the data history to demonstrate the consequences particular theoretical and methodological approaches pose in producing knowledge claims and inciting dialogues across traditions. The article demonstrates how theory-method-claim relationships in transcribing influence research transparency and warrantability. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1201146

Review Essay: From Local Practices to Public Knowledge: Action Research as Scientific Contribution

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Joel Martí

2008-07-01

Full Text Available In recent years action research has been gradually introduced into academic thought, giving impetus to contributions such as The Action Research Dissertation, specifically aimed at doing and reporting doctoral research based on this methodology. Beyond purely instrumental aspects (contributing criteria and tools for the execution of dissertations through action research, the book raises some issues that play a fundamental role in assessing action research at the university level: its epistemological bases, researchers' positionality, quality criteria, and the ways in which the process is narrated. This review essay introduces the debate (Section 1, reviews the chapters of the book (Section 2, and notes its contributions to this ongoing discussion and where it falls short, and, more generally, on the relation between universities, action research, and social practices (Section 3. URN: urn:nbn:de:0114-fqs080320

Auto/Ethnography and the Question of Ethics

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Wolff-Michael Roth

2008-10-01

Full Text Available Auto/ethnography has emerged as an important method in the social sciences for contributing to the project of understanding human actions and concerns. Although the name of the method includes "ethnography," auto/ethnography often is concerned exclusively with an abstract (i.e., undeveloped and abstracting understanding, and therefore the writing, of the Self rather than the writing of the "ethno." Auto/ethnography, such conceived, is a form of therapy, in the best case, and a form of narcissism and autoerotic relation, in the worst case. But because the Self exists in relation to the world, becomes in and through participation in everyday events, and because the human relation is inherently ethical, there are inherent ethical questions where the Other may come to be harmed as much as the Self. URN: urn:nbn:de:0114-fqs0901381

The Field of Foucaultian Discourse Analysis: Structures, Developments and Perspectives

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Rainer Diaz-Bone

2007-05-01

Full Text Available The article outlines the field of FOUCAULTian discourse analysis. The FOUCAULTian concept of discourse is introduced, and methodological positions and methodological developments are sketched. Compared to other qualitative social research approaches, the different researchers and research groups that have adopted the FOUCAULTian concept of discourse are not linked by a fully integrated common research paradigm. However, they share common methodological problems and areas of methodological research resulting from various references to FOUCAULTian positions. In the last decade, different research groups have become aware of these shared commonalities, so that one can speak of an emerging field of FOUCAULTian discourse analysis rather than an emerging paradigm. The article gives insight into the discourse analytic research in selected countries, discusses the internationalisation of FOUCAULTian discourse analysis and highlights current trends and perspectives. URN: urn:nbn:de:0114-fqs0702305

Music Teachers' Personal Concepts: Qualitative Classroom Research in Music Education

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Anne Niessen

2008-01-01

Full Text Available How do music teachers reflect on planning and performing school lessons? How do their experiences influence their teaching arrangements? In a qualitative research project the author uses the "Individualkonzept" (personal concept to explore what music teachers think while planning music lessons. In addition, the relationship between personal concepts and biographical experiences is investigated. In accordance with grounded theory methodology, interviews with teachers were analyzed first at the level of the single interviews; followed by developing a grounded theory about the music teachers' personal concepts and their embedding in biography. In doing so an integrative pattern emerged unfolding in time as a learning process. Results of the research suggest finding forms of in-service-training for teachers that will allow them to foster a self-conscious acquaintance with their own biographical background. URN: urn:nbn:de:0114-fqs080178

A Personal Journey with Grounded Theory Methodology. Kathy Charmaz in Conversation With Reiner Keller

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Kathy Charmaz

2016-01-01

Full Text Available Kathy CHARMAZ is one of the most important thinkers in grounded theory methodology today. Her trailblazing work on constructivist grounded theory continues to inspire research across many disciplines and around the world. In this interview, she reflects on the aura surrounding qualitative inquiry that existed in California in the late 1960s to early 1970s and the lessons she learned from her first forays into empirical research. She comments on the trajectory that grounded theory research has followed since then and gives an account of her own perspective on constructivist grounded theory. In doing so, she underlines the importance of the Chicago School and symbolic interactionist tradition for grounded theory research work today and shows where the latter is positioned in the current field of qualitative fieldwork. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1601165

Con en el desierto en el cuerpo. Mapas performáticos de jóvenes chilenas

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Jimena Silva

2014-01-01

Full Text Available Para comprender las ideologías basadas en el género, esta es una investigación cualitativaque usóun modelo metodológico basado en mapas corporales, entrevistas y análisis intertextual de 47 estudiantes antofagastinas de las zonas mineras del norte chileno. En el análisis interpretativo de los elementos simbólicos en los mapas corporales se encontró que los mineros ven metafóricamente el cuerpo femenino como: cuerpo/mina, como agujero/penetrable (mujer como objeto sexual donde puede extraerse tesoro/riqueza. Las expresiones del cuerpo femenino, en tanto agente/transformador establecen un diálogo tenso en el que el poder de la mujer es perturbador en una cultura en la que el hombre es dominador. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs140175

Biographical Storytelling in the Context of Counseling and Therapy

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Heidrun Schulze

2008-01-01

Full Text Available A precondition for any hermeneutic analysis of biographies is that the interview partners generate life history narratives. The same applies to a counseling practice that is sensitized by biographical analysis. On the one hand, clients' narratives of their own experiences provide the counselor with information on their biographical self-constructions and the processes of the sedimentation of the experiences of their life history. On the other hand, such narratives are not only of diagnostic use for the counselor, but also contribute to the clients' self-understanding. The author works in a psychosocial counseling center for university students. The article describes the transfer and potential of a style of counseling which encourages and is sensitized by biographical narratives in the context of an institution with a specific task. URN: urn:nbn:de:0114-fqs080117

Review: Gerald Beck (2013. Sichtbare Soziologie. Visualisierung und soziologische Wissenschaftskommunikation in der Zweiten Moderne

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Axel Philipps

2014-01-01

Full Text Available Visualisierungen von Wissen hatten und haben im Kern des Faches Soziologie einen schweren Stand. Gerald BECK nimmt sich daher in seinem Buch "Sichtbare Soziologie" der Thematik an, um die Stellung von Visualisierungen in der Soziologie zu verstehen, damit verbundene Problemfelder zu identifizieren und für visuelle Umsetzungen zu sensibilisieren. Er setzt dazu beim Übergang zur Zweiten Moderne an und betrachtet anhand von neun Fallbeispielen gelungene und weniger gelungene Visualisierungen. Durch die verkürzte Aufarbeitung des Verhältnisses der Soziologie zum Bild bleiben jedoch wichtige Einsichten unberücksichtigt, sodass BECKs Empfehlungen, die Zahl der Visualisierungen und die visuelle Kompetenz zu erhöhen, kaum geeignet sind, die Skepsis in der Soziologie gegenüber Visualisierungen zu überwinden. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1401228

Review: Bettina Fritzsche (2003. Pop-Fans. Studie einer Mädchenkultur [Pop-Fans: Study of a Girl Culture

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Lothar Mikos

2006-05-01

Full Text Available This study focuses on the "girl culture" created by fans of boy groups and girl groups. The central case study is used to examine fan practices as cultural practices using reconstructive and documentary methodologies, and to assess the normative demands placed on young people. The study centers on the question of gender socialization by mediated symbolic resources, and shows that fan culture is a self-determined space in which girls can negotiate normative demands and engage with questions of gender, sexuality and the body, testing conformity and obstinacy. Fan activities are presented as part of the self-empowerment of girls. The study makes an important contribution to the research of a specific girl culture. It shows in a brilliant way how media representations are used as symbolic material in everyday cultural practices. URN: urn:nbn:de:0114-fqs0603187

Was that Infinity or Affinity? Applying Insights from Translation Studies to Qualitative Research Transcription

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Jen Ross

2010-02-01

Full Text Available Despite a small but compelling body of literature arguing that transcription represents a key moment of choice and the exercise of power in the research process, many qualitative researchers appear to believe (or at least proceed as if they believe that transcription is relatively unproblematic. Translation studies and its engagement with visibility, power, authenticity and fidelity has a lot to offer to qualitative researchers working critically with transcription theory and practice. This paper explores the translation studies theories of equivalence, overt and covert translation, foreignisation and domestication, and the remainder, and demonstrates some fertile connections between transcription and translation. These connections help us to think about some broader political and cultural issues in relation to transcription and academic discourse, the complexity of equivalence and the central role of the situated transcriber. URN: urn:nbn:de:0114-fqs100223

"Guess What?": On Hidden-Camera Pranks' Revelation Sequences

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A. Javier Izquierdo-Martín

2004-05-01

Full Text Available Conceived as public communication objects, hidden-camera pranks (HCPs are a type of documentary on ordinary pranks. Defined versus classical Garfinkelian breaching experiments, HCPs also offer a natural form of ethnomethodological experimentation. Here I present some results of an analysis of a sample of forty-nine HCPs' revelation sequences (RSs. These little clips of five to fifty seconds long allow for the description of audio-visual details of the interactional work that actors, accomplices and victims of a HCP have to perform, in a finely coordinated manner in order "to put an end" to an artificially constructed social situation. My study focuses on a set of practical relevances of the work of revelation (offering and awakening (acceptation/rejection endogenously pointed at and topicalized by the agents enmeshed in the HCP situation. URN: urn:nbn:de:0114-fqs0402126

Review Essay: Zur Relevanz des ethnografischen Blicks bei der sozial- und kulturwissenschaftlichen Erforschung von Orten und Räumen [Researching Place and Space in the Social Sciences and Cultural Studies: The Relevance of the Ethnographic Approach

Directory of Open Access Journals (Sweden)

Cornelia Siebeck

2011-09-01

Full Text Available Given the so-called "spatial turn" in the social sciences and cultural studies, social geographers have rightfully been cautioning against positivist notions of space and place: We cannot simply deduce the social from spatial reality—on the contrary, this reality is in every respect itself socially constituted and mediated. In her highly recommended study on the esthetical and socio-political reshaping of Alexanderplatz in Berlin after 1990, Gisa WESZKALNYS has shown how a radical constructivist concept of place and space can be transformed into practical research. This review essay argues that an ethnographic research perspective is of particular relevance both epistemologically as well as methodologically if the aim is to reconstruct places and spaces beyond their perceived "actuality" in terms of a fundamentally contingent social and essentially political practice. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1103203