Results of the independent radiological verification survey at the former Associate Aircraft Tool and Manufacturing Company site, Fairfield, Ohio (FOH001)

International Nuclear Information System (INIS)

Rice, D.E.; Murray, M.E.; Brown, K.S.

1996-01-01

The former Associate Aircraft Tool and Manufacturing Company site is located at 3550 Dixie Highway, Fairfield, Ohio. Associate Aircraft Tool and Manufacturing Company produced hollow uranium slugs in a machine shop at the site in 1956. The work was performed for National Lead of Ohio in a contract with the Atomic Energy Commission to augment the capacity of the Feed Materials Production Center at Fernald in the development of nuclear energy for defense-related projects. The current occupant of the building, Force Control, operates a multipurpose machine shop. At the request of the US Department of Energy (DOE), a team from Oak Ridge National Laboratory conducted an independent radiological verification survey at the former Associate Aircraft Tool and Manufacturing Company Site, Fairfield, Ohio. The survey was performed from February to May of 1995. The purpose of the survey was to verify that radioactivity from residues of 238 U was remediated to a level below acceptable DOE guidelines levels

Human resource factors associated with workplace safety and health education of small manufacturing businesses in Korea.

Science.gov (United States)

Park, Kyoung-Ok

2018-01-25

Human resources (HR) are essential indicators of safety and health (SH) status, and HR can be key sources of workplace safety management such as safety and health education at work (SHEW). This study analyzed significant HR factors associated with SHEW of small manufacturing businesses in Korea. The secondary data of the 2012 Korea Occupational Safety and Health Trend Survey were used to achieve this research purpose. A total of 2,089 supervisors or managers employed in the small manufacturing businesses completed the interview survey. Survey businesses were selected by multiple stratified sampling method based on industry code, business size, and region in Korea. The survey included workplace characteristics of HR and SHEW. SHEW was significantly related to business size, occupational injury incidence in the previous year, foreign and elderly worker employment, presence of site supervisors, and presence of SH committees (p <.05). SHEW for office workers, non-office workers, and newcomers was associated with business size, presence of site supervisors, and presence of SH committees in logistic regression analysis (p <.001). Businesses with 30-49 workers conducted SHEW 3.64 times more than did businesses with 5 to fewer than 10 workers. The companies that had occupational injuries in the previous year conducted SHEW 1.68 times more than the others. The businesses that had site supervisors and committees conducted SHEW 2.30 and 2.18 times more, respectively, than others. Site supervisors and SH committees were significant HR factors that improved SHEW in small manufacturing businesses.

Proceedings of the 1991 Oil Heat Technology Conference and Workshop

Energy Technology Data Exchange (ETDEWEB)

McDonald, R.J.

1992-07-01

This Conference, which was the sixth held since 1984, is a key technology-transfer activity supported by the ongoing Combustion Equipment Technology program at BNL, and is aimed at providing a forum for the exchange of information among international researchers, engineers, manufacturers, and marketers of oil-fired space-conditioning equipment. The objectives of the Conference were to: Identify and evaluate the state-of-the-art and recommend; new initiatives to satisfy consumer needs cost-effectively, reliably, and safely; Foster cooperation among federal and industrial representatives with the common goal of national security via energy conservation. The 1991 Oil Technology Conference comprised: (a) two plenary sessions devoted to presentations and summations by public and private sector representatives from the United States, Europe, and Canada; and, (b) four workshops which focused on mainstream issues in oil-heating technology. Selected papers have been processed separately for inclusion in the Energy Science and Technology Database.

Rapid Response Manufacturing (RRM). Final CRADA report

Energy Technology Data Exchange (ETDEWEB)

Cain, W.D. [Lockheed Martin Energy Systems, Inc., Oak Ridge, TN (United States); Waddell, W.L. [National Centers for Manufacturing Sciences, Ann Arbor, MI (United States)

1997-08-28

A major accomplishment of the Rapid Response Manufacturing (RRM) project was the development of a broad-based generic framework for automating and integrating the design-to-manufacturing activities associated with machined part products. Key components of the framework are a manufacturing model that integrates product and process data in a consistent, minimally redundant manner, an advanced computer-aided engineering working environment, knowledge-based software systems for design, process planning, and manufacturing and new production technologies for making products directly from design application software.

Biocompatibility of Advanced Manufactured Titanium Implants—A Review

Science.gov (United States)

Sidambe, Alfred T.

2014-01-01

Titanium (Ti) and its alloys may be processed via advanced powder manufacturing routes such as additive layer manufacturing (or 3D printing) or metal injection moulding. This field is receiving increased attention from various manufacturing sectors including the medical devices sector. It is possible that advanced manufacturing techniques could replace the machining or casting of metal alloys in the manufacture of devices because of associated advantages that include design flexibility, reduced processing costs, reduced waste, and the opportunity to more easily manufacture complex or custom-shaped implants. The emerging advanced manufacturing approaches of metal injection moulding and additive layer manufacturing are receiving particular attention from the implant fabrication industry because they could overcome some of the difficulties associated with traditional implant fabrication techniques such as titanium casting. Using advanced manufacturing, it is also possible to produce more complex porous structures with improved mechanical performance, potentially matching the modulus of elasticity of local bone. While the economic and engineering potential of advanced manufacturing for the manufacture of musculo-skeletal implants is therefore clear, the impact on the biocompatibility of the materials has been less investigated. In this review, the capabilities of advanced powder manufacturing routes in producing components that are suitable for biomedical implant applications are assessed with emphasis placed on surface finishes and porous structures. Given that biocompatibility and host bone response are critical determinants of clinical performance, published studies of in vitro and in vivo research have been considered carefully. The review concludes with a future outlook on advanced Ti production for biomedical implants using powder metallurgy. PMID:28788296

Biocompatibility of Advanced Manufactured Titanium Implants—A Review

Directory of Open Access Journals (Sweden)

Alfred T. Sidambe

2014-12-01

Full Text Available Titanium (Ti and its alloys may be processed via advanced powder manufacturing routes such as additive layer manufacturing (or 3D printing or metal injection moulding. This field is receiving increased attention from various manufacturing sectors including the medical devices sector. It is possible that advanced manufacturing techniques could replace the machining or casting of metal alloys in the manufacture of devices because of associated advantages that include design flexibility, reduced processing costs, reduced waste, and the opportunity to more easily manufacture complex or custom-shaped implants. The emerging advanced manufacturing approaches of metal injection moulding and additive layer manufacturing are receiving particular attention from the implant fabrication industry because they could overcome some of the difficulties associated with traditional implant fabrication techniques such as titanium casting. Using advanced manufacturing, it is also possible to produce more complex porous structures with improved mechanical performance, potentially matching the modulus of elasticity of local bone. While the economic and engineering potential of advanced manufacturing for the manufacture of musculo-skeletal implants is therefore clear, the impact on the biocompatibility of the materials has been less investigated. In this review, the capabilities of advanced powder manufacturing routes in producing components that are suitable for biomedical implant applications are assessed with emphasis placed on surface finishes and porous structures. Given that biocompatibility and host bone response are critical determinants of clinical performance, published studies of in vitro and in vivo research have been considered carefully. The review concludes with a future outlook on advanced Ti production for biomedical implants using powder metallurgy.

Biocompatibility of Advanced Manufactured Titanium Implants-A Review.

Science.gov (United States)

Sidambe, Alfred T

2014-12-19

Titanium (Ti) and its alloys may be processed via advanced powder manufacturing routes such as additive layer manufacturing (or 3D printing) or metal injection moulding. This field is receiving increased attention from various manufacturing sectors including the medical devices sector. It is possible that advanced manufacturing techniques could replace the machining or casting of metal alloys in the manufacture of devices because of associated advantages that include design flexibility, reduced processing costs, reduced waste, and the opportunity to more easily manufacture complex or custom-shaped implants. The emerging advanced manufacturing approaches of metal injection moulding and additive layer manufacturing are receiving particular attention from the implant fabrication industry because they could overcome some of the difficulties associated with traditional implant fabrication techniques such as titanium casting. Using advanced manufacturing, it is also possible to produce more complex porous structures with improved mechanical performance, potentially matching the modulus of elasticity of local bone. While the economic and engineering potential of advanced manufacturing for the manufacture of musculo-skeletal implants is therefore clear, the impact on the biocompatibility of the materials has been less investigated. In this review, the capabilities of advanced powder manufacturing routes in producing components that are suitable for biomedical implant applications are assessed with emphasis placed on surface finishes and porous structures. Given that biocompatibility and host bone response are critical determinants of clinical performance, published studies of in vitro and in vivo research have been considered carefully. The review concludes with a future outlook on advanced Ti production for biomedical implants using powder metallurgy.

Quality prediction modeling for multistage manufacturing based on classification and association rule mining

Directory of Open Access Journals (Sweden)

Kao Hung-An

2017-01-01

Full Text Available For manufacturing enterprises, product quality is a key factor to assess production capability and increase their core competence. To reduce external failure cost, many research and methodology have been introduced in order to improve process yield rate, such as TQC/TQM, Shewhart CycleDeming's 14 Points, etc. Nowadays, impressive progress has been made in process monitoring and industrial data analysis because of the Industry 4.0 trend. Industries start to utilize quality control (QC methodology to lower inspection overhead and internal failure cost. Currently, the focus of QC is mostly in the inspection of single workstation and final product, however, for multistage manufacturing, many factors (like equipment, operators, parameters, etc. can have cumulative and interactive effects to the final quality. When failure occurs, it is difficult to resume the original settings for cause analysis. To address these problems, this research proposes a combination of principal components analysis (PCA with classification and association rule mining algorithms to extract features representing relationship of multiple workstations, predict final product quality, and analyze the root-cause of product defect. The method is demonstrated on a semiconductor data set.

Work-related depression and associated factors in a shoe manufacturing factory in Haiphong City, Vietnam

Directory of Open Access Journals (Sweden)

Khue Pham Minh

2014-12-01

Full Text Available Objectives: To determine the prevalence and associated factors of work-related depression among the employees of a shoe manufacturing factory in Haiphong City, Vietnam. Material and Methods: We carried out this cross-sectional study among 420 workers in 2012 in Le Lai II Shoe Manufacturing Factory in Haiphong City, Vietnam using Karasek’s Job Content Questionnaire (JCQ and the Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM IV tool for measuring depression. Results: The study results show that a relatively high proportion of workers (20.7% belongs to the high-strain group based on Karasek’s model. The prevalence of work-related depression among workers was relatively high (18.8%. The factors associated with depression at work were high psychological demand (adjusted OR = 3.0, 95% CI: 1.1–8.3, low social support (adjusted OR = 4.7, 95% CI: 1.2–12.8, inadequate work protection materials (OR = 4.1, 95% CI: 2.2–10.1 and work absenteeism (OR = 6.2, 95% CI: 2.5–18.9. Conclusions: Strengthening the social support network (involving supervisors and co‑workers, reducing psychological job demand and assuring work protection materials at the workplace may highly facilitate reducing work-related depression.

The relationships between Lean manufacturing, management accounting and firm performance

DEFF Research Database (Denmark)

Kristensen, Thomas Borup; Nielsen, Henrik; Grasso, Lawrency

2016-01-01

with management accounting practices. Specifically, we document that Lean manufacturing is positively associated with Value Stream Costing, Lean visual controls and, more importantly, measures of labor and materials efficiency. Lean manufacturing is positively related to Lean thinking and both are positively...... associated with operational performance and so are Lean visual controls. We also document that the management accounting practices intervene affecting operational performance and they intervene with Lean thinking as well. Lastly, the relationship between Lean manufacturing and measures of labor and materials......Lean manufacturing has been adopted by numerous western companies as an answer to an increasing competitive environment. Lean manufacturing is seen as an enterprise-wide strategy encompassing a transformation of manufacturing practices, affecting companies’ management accounting practices and...

Risk calculations in the manufacturing technology selection process

DEFF Research Database (Denmark)

Farooq, S.; O'Brien, C.

2010-01-01

Purpose - The purpose of this paper is to present result obtained from a developed technology selection framework and provide a detailed insight into the risk calculations and their implications in manufacturing technology selection process. Design/methodology/approach - The results illustrated...... in the paper are the outcome of an action research study that was conducted in an aerospace company. Findings - The paper highlights the role of risk calculations in manufacturing technology selection process by elaborating the contribution of risk associated with manufacturing technology alternatives...... in the shape of opportunities and threats in different decision-making environments. Practical implications - The research quantifies the risk associated with different available manufacturing technology alternatives. This quantification of risk crystallises the process of technology selection decision making...

Automation and Integration in Semiconductor Manufacturing

OpenAIRE

Liao, Da-Yin

2010-01-01

Semiconductor automation originates from the prevention and avoidance of frauds in daily fab operations. As semiconductor technology and business continuously advance and grow, manufacturing systems must aggressively evolve to meet the changing technical and business requirements in this industry. Semiconductor manufacturing has been suffering pains from islands of automation. The problems associated with these systems are limited

The impact of fit manufacturing on green manufacturing: A review

Science.gov (United States)

Qi, Ang Nian; Sin, Tan Chan; Fathullah, M.; Lee, C. C.

2017-09-01

Fit manufacturing and Green manufacturing are a new trend principle and concept. They are getting popular in industrial. This paper is identifying the impact between Fit manufacturing and Green manufacturing. Besides Fit manufacturing, Lean manufacturing, Agile manufacturing and Sustainable manufacturing gives big impacts to Green Manufacturing. On top of that, this paper also discuss the benefits of applying Fit manufacturing and Green manufacturing in industrial as well as environment. Hence, applications of Fit manufacturing and Green Manufacturing are increasing year by year.

Composites Materials and Manufacturing Technologies for Space Applications

Science.gov (United States)

Vickers, J. H.; Tate, L. C.; Gaddis, S. W.; Neal, R. E.

2016-01-01

Composite materials offer significant advantages in space applications. Weight reduction is imperative for deep space systems. However, the pathway to deployment of composites alternatives is problematic. Improvements in the materials and processes are needed, and extensive testing is required to validate the performance, qualify the materials and processes, and certify components. Addressing these challenges could lead to the confident adoption of composites in space applications and provide spin-off technical capabilities for the aerospace and other industries. To address the issues associated with composites applications in space systems, NASA sponsored a Technical Interchange Meeting (TIM) entitled, "Composites Materials and Manufacturing Technologies for Space Applications," the proceedings of which are summarized in this Conference Publication. The NASA Space Technology Mission Directorate and the Game Changing Program chartered the meeting. The meeting was hosted by the National Center for Advanced Manufacturing (NCAM)-a public/private partnership between NASA, the State of Louisiana, Louisiana State University, industry, and academia, in association with the American Composites Manufacturers Association. The Louisiana Center for Manufacturing Sciences served as the coordinator for the TIM.

Rapsodie first core manufacture. 1. part: processing plant

International Nuclear Information System (INIS)

Masselot, Y.; Bataller, S.; Ganivet, M.; Guillet, H.; Robillard, A.; Stosskopf, F.

1968-01-01

This report is the first in a series of three describing the processes, results and peculiar technical problems related to the manufacture of the first core of the fast reactor Rapsodie. A detailed study of manufacturing processes(pellets, pins, fissile sub-assemblies), the associated testings (raw materials, processed pellets and pins, sub-assemblies before delivery), manufacturing facilities and improvements for a second campaign are described. (author) [fr

Proceedings of the 1998 oil heat technology conference

Energy Technology Data Exchange (ETDEWEB)

McDonald, R.J.

1998-04-01

The 1998 Oil Heat Technology Conference was held on April 7--8 at Brookhaven National Laboratory (BNL) under sponsorship by the US Department of Energy, Office of Building Technologies, State and Community Programs (DOE/BTS). The meeting was held in cooperation with the Petroleum Marketers Association of America (PMAA). Fourteen technical presentations was made during the two-day program, all related to oil-heat technology and equipment, these will cover a range of research, developmental, and demonstration activities being conducted within the United States and Canada, including: integrated oil heat appliance system development in Canada; a miniature heat-actuated air conditioner for distributed space conditioning; high-flow fan atomized oil burner (HFAB) development; progress in the development of self tuning oil burners; application of HFAB technology to the development of a 500 watt; thermophotovoltaic (TPV) power system; field tests of the Heat Wise Pioneer oil burner and Insight Technologies AFQI; expanded use of residential oil burners to reduce ambient ozone and particulate levels by conversion of electric heated homes to oilheat; PMAA`s Oil Heat Technician`s Manual (third edition); direct venting concept development; evolution of the chimney; combating fuel related problems; the effects of red dye and metal contamination on fuel oil stability; new standard for above ground and basement residential fuel oil storage; plastic and steel composite secondary contained tanks; and money left on the table: an economic analysis of tank cleaning.

Control systems engineering in continuous pharmaceutical manufacturing. May 20-21, 2014 Continuous Manufacturing Symposium.

Science.gov (United States)

Myerson, Allan S; Krumme, Markus; Nasr, Moheb; Thomas, Hayden; Braatz, Richard D

2015-03-01

drug manufacturing that are easily transportable to industry. Industry can facilitate the move to continuous manufacturing by working with universities on the conception of new continuous pharmaceutical manufacturing process unit operations that have the potential to make major improvements in product quality, controllability, or reduced capital and/or operating costs. Regulatory bodies should ensure that: (1) regulations and regulatory practices promote, and do not derail, the development and implementation of continuous manufacturing and control systems engineering approaches; (2) the individuals who approve specific regulatory filings are sufficiently trained to make good decisions regarding control systems approaches; (3) provide regulatory clarity and eliminate/reduce regulatory risks; (4) financially support the development of high-quality training materials for use of undergraduate students, graduate students, industrial employees, and regulatory staff; (5) enhance the training of their own technical staff by financially supporting joint research projects with universities in the development of continuous pharmaceutical manufacturing processes and the associated control systems engineering theory, numerical algorithms, and software; and (6) strongly encourage the federal agencies that support research to fund these research areas. © 2014 Wiley Periodicals, Inc. and the American Pharmacists Association.

The complexity and cost of vaccine manufacturing - An overview.

Science.gov (United States)

Plotkin, Stanley; Robinson, James M; Cunningham, Gerard; Iqbal, Robyn; Larsen, Shannon

2017-07-24

As companies, countries, and governments consider investments in vaccine production for routine immunization and outbreak response, understanding the complexity and cost drivers associated with vaccine production will help to inform business decisions. Leading multinational corporations have good understanding of the complex manufacturing processes, high technological and R&D barriers to entry, and the costs associated with vaccine production. However, decision makers in developing countries, donors and investors may not be aware of the factors that continue to limit the number of new manufacturers and have caused attrition and consolidation among existing manufacturers. This paper describes the processes and cost drivers in acquiring and maintaining licensure of childhood vaccines. In addition, when export is the goal, we describe the requirements to supply those vaccines at affordable prices to low-resource markets, including the process of World Health Organization (WHO) prequalification and supporting policy recommendation. By providing a generalized and consolidated view of these requirements we seek to build awareness in the global community of the benefits and costs associated with vaccine manufacturing and the challenges associated with maintaining consistent supply. We show that while vaccine manufacture may prima facie seem an economic growth opportunity, the complexity and high fixed costs of vaccine manufacturing limit potential profit. Further, for most lower and middle income countries a large majority of the equipment, personnel and consumables will need to be imported for years, further limiting benefits to the local economy. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

An Interoperability Framework and Capability Profiling for Manufacturing Software

Science.gov (United States)

Matsuda, M.; Arai, E.; Nakano, N.; Wakai, H.; Takeda, H.; Takata, M.; Sasaki, H.

ISO/TC184/SC5/WG4 is working on ISO16100: Manufacturing software capability profiling for interoperability. This paper reports on a manufacturing software interoperability framework and a capability profiling methodology which were proposed and developed through this international standardization activity. Within the context of manufacturing application, a manufacturing software unit is considered to be capable of performing a specific set of function defined by a manufacturing software system architecture. A manufacturing software interoperability framework consists of a set of elements and rules for describing the capability of software units to support the requirements of a manufacturing application. The capability profiling methodology makes use of the domain-specific attributes and methods associated with each specific software unit to describe capability profiles in terms of unit name, manufacturing functions, and other needed class properties. In this methodology, manufacturing software requirements are expressed in terns of software unit capability profiles.

Transformation of Manufacturing Firms to Servitisation Firms

DEFF Research Database (Denmark)

Lin, Chih-Cheng; Ma, Zheng; Tanev, Stoyan

2014-01-01

It is crucial for the manufacturing SMEs to reconsider their business strategy in order to be able to launch customer-centric solutions. This ability is associated with a paradigm shift from a product-orientation to service-orientation. One of the major challenges to success in transforming...... a traditional manufacturing firm to service-oriented firms is the conspicuous lack of publications in this research stream. Applying a case study research approach, this study explores the transformation model for manufacturing SMEs to servitisation firms by adopting a network approach, and reveals...

Social manufacturing

OpenAIRE

Hamalainen, Markko; Karjalainen, Jesse

2017-01-01

New business models harnessing the power of individuals have already revolutionized service industries and digital content production. In this study, we investigate whether a similar phenomenon is taking place in manufacturing industries. We start by conceptually defining two distinct forms of firm-individual collaboration in manufacturing industries: (1) social cloud manufacturing, in which firms outsource manufacturing to individuals, and (2) social platform manufacturing, in which firms pr...

Practical Aspects of CALS in Design and Manufacturing of Sheet Metal Products

DEFF Research Database (Denmark)

Shpitalni, Moshe; Alting, Leo; Bilberg, Arne

1998-01-01

The transition from design to process planning and to the various stages of manufacturing is traditionally sequential. In many cases, practical problems associated with manufacturing cannot be resolved if only individual processes are examined. These problems can be overcome, however, by adopting...... with the design and manufacture of sheet metal parts. It is demonstrated that through implementation of the CALS approach, the overall process can be optimised and products can be manufactured significantly more accurately, faster and less expensively.......The transition from design to process planning and to the various stages of manufacturing is traditionally sequential. In many cases, practical problems associated with manufacturing cannot be resolved if only individual processes are examined. These problems can be overcome, however, by adopting...

Spring 2008 Industry Study. Manufacturing Industry

Science.gov (United States)

2008-01-01

Chamber of Commerce puts the number of U.S. manufacturing jobs lost to piracy at 750,000 (U.S. Chamber of Commerce , 2007). Interviews with...economy each year and puts millions at risk from counterfeit medicines and engine parts (U.S. Chamber of Commerce , 2007). There are, however, several...Association of Manufacturers (NAM) and the U.S. Chamber of Commerce advocate global changes to IP protection, calling for the “reform and harmonization

Centers for manufacturing technology: Industrial Advisory Committee Review

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-10-01

An advisory committee, composed of senior managers form industrial- sector companies and major manufacturing trade associations and representatives from appropriate educational institutions, meets semi-annually to review and advise the Oak Ridge Centers for Manufacturing Technology (ORCMT) on its economic security program. Individual papers have been indexed separately for the database.

Precision manufacturing

CERN Document Server

Dornfeld, David

2008-01-01

Today there is a high demand for high-precision products. The manufacturing processes are now highly sophisticated and derive from a specialized genre called precision engineering. Precision Manufacturing provides an introduction to precision engineering and manufacturing with an emphasis on the design and performance of precision machines and machine tools, metrology, tooling elements, machine structures, sources of error, precision machining processes and precision process planning. As well as discussing the critical role precision machine design for manufacturing has had in technological developments over the last few hundred years. In addition, the influence of sustainable manufacturing requirements in precision processes is introduced. Drawing upon years of practical experience and using numerous examples and illustrative applications, David Dornfeld and Dae-Eun Lee cover precision manufacturing as it applies to: The importance of measurement and metrology in the context of Precision Manufacturing. Th...

21ST Century Manufacturing Enterprise Strategy Report

Science.gov (United States)

1992-01-01

Association for Manufacturing Excellence, Wheeling, Illinois, 28 p. 142. Hamel, G.; Prahalad , C.K. (1989): " Strategic Intent ". Harvard Business...counsel of over 150 people from 77 companies and I1I professional organizations in developing their strategic enterprise plan. The group strongly...Understand the strategic implications of manufacturing technology for the corporation (4) Have a vision of the future competitiveness needs of industry in

Manufacturing of nuclear power components in CDM

International Nuclear Information System (INIS)

Krishnan, J.; Jawale, S.B.

2002-01-01

Full text: In the nuclear research programme in India, Dr. H.J. Bhabha, the architecture of the Indian Nuclear programme felt a need for proto-type development and precision manufacturing facility to fulfill the requirements of mechanical components in establishing the manufacturing capability for the successful and self sustained nuclear programme. Centre for Design and Manufacture (CDM) hitherto known as CWS was established in 1964 to cater to the specific requirements of DAE and other associated units like ISRO, DRDO. Since then CDM has made multiple technological achievements and changes towards high quality products. The acquisition of up-to-date machines during High-Tech facility under VIII Plan project and Advance Precision Fabrication facility under IX Plan project has changed the capability of CDM towards CAD, CAM, CAE and CNC machining centres. Considering the rapid growth in the design and manufacturing, it was renamed as Centre for Design and Manufacture in March 2002, with the mission of quality output through group effort and team work

Manufacturing network evolution

DEFF Research Database (Denmark)

Yang, Cheng; Farooq, Sami; Johansen, John

2011-01-01

Purpose – This paper examines the effect of changes at the manufacturing plant level on other plants in the manufacturing network and also investigates the role of manufacturing plants on the evolution of a manufacturing network. Design/methodology/approach –The research questions are developed...... different manufacturing plants in the network and their impact on network transformation. Findings – The paper highlights the dominant role of manufacturing plants in the continuously changing shape of a manufacturing network. The paper demonstrates that a product or process change at one manufacturing...... by identifying the gaps in the reviewed literature. The paper is based on three case studies undertaken in Danish manufacturing companies to explore in detail their manufacturing plants and networks. The cases provide a sound basis for developing the research questions and explaining the interaction between...

Bioprinting: an assessment based on manufacturing readiness levels.

Science.gov (United States)

Wu, Changsheng; Wang, Ben; Zhang, Chuck; Wysk, Richard A; Chen, Yi-Wen

2017-05-01

Over the last decade, bioprinting has emerged as a promising technology in the fields of tissue engineering and regenerative medicine. With recent advances in additive manufacturing, bioprinting is poised to provide patient-specific therapies and new approaches for tissue and organ studies, drug discoveries and even food manufacturing. Manufacturing Readiness Level (MRL) is a method that has been applied to assess manufacturing maturity and to identify risks and gaps in technology-manufacturing transitions. Technology Readiness Level (TRL) is used to evaluate the maturity of a technology. This paper reviews recent advances in bioprinting following the MRL scheme and addresses corresponding MRL levels of engineering challenges and gaps associated with the translation of bioprinting from lab-bench experiments to ultimate full-scale manufacturing of tissues and organs. According to our step-by-step TRL and MRL assessment, after years of rigorous investigation by the biotechnology community, bioprinting is on the cusp of entering the translational phase where laboratory research practices can be scaled up into manufacturing products specifically designed for individual patients.

Lean Manufacturing Auto Cluster at Chennai

Science.gov (United States)

Bhaskaran, E.

2012-10-01

Due the presence of lot of automotive Industry, Chennai is known as Detroit of India, that producing over 40 % of the Indian vehicle and components. Lean manufacturing concepts have been widely recognized as an important tool in improving the competitiveness of industries. This is a continuous process involving everyone, starting from management to the shop floor. Automotive Component Industries (ACIs) in Ambattur Industrial Estate, Chennai has formed special purpose vehicle (SPV) society namely Ambattur Industrial Estate Manufacturers Association (AIEMA) Technology Centre (ATC) lean manufacturing cluster (ATC-LMC) during July 2010 under lean manufacturing competitiveness scheme, that comes under National Manufacturing Competitiveness Programme of Government of India. The Tripartite Agreement is taken place between National Productivity Council, consultants and cluster (ATC-LMC). The objective is to conduct diagnostic study, study on training and application of various lean manufacturing techniques and auditing in ten ACIs. The methodology adopted is collection of primary data/details from ten ACIs. In the first phase, diagnostic study is done and the areas for improvement in each of the cluster member companies are identified. In the second phase, training programs and implementation is done on 5S and other areas. In the third phase auditing is done and found that the lean manufacturing techniques implementation in ATC-LMC is sustainable and successful in every cluster companies, which will not only enhance competitiveness but also decrease cost, time and increase productivity. The technical efficiency of LMC companies also increases significantly.

Experience with quality assurance in fuel design and manufacturing

International Nuclear Information System (INIS)

Holzer, R.; Nilson, F.

1984-01-01

The Quality Assurance/Quality Control activities for nuclear fuel design and manufacturing described here are coordinated under a common ''Quality Assurance System For Fuel Assemblies and Associated Core Components'' which regulates the QA-functions of the development, design and manufacturing of fuel assemblies independent of the organizational assignment of the contributing technical groups. Some essential characteristics of the system are shown, using examples from design control, procurement, manufacturing and qualification of special processes. The experience is very good, it allowed a flexible and well controlled implementation of design and manufacturing innovations and contributed to the overall good fuel behavior. (orig.)

Laser 3D micro-manufacturing

International Nuclear Information System (INIS)

Piqué, Alberto; Auyeung, Raymond C Y; Kim, Heungsoo; Charipar, Nicholas A; Mathews, Scott A

2016-01-01

Laser-based materials processing techniques are gaining widespread use in micro-manufacturing applications. The use of laser microfabrication techniques enables the processing of micro- and nanostructures from a wide range of materials and geometries without the need for masking and etching steps commonly associated with photolithography. This review aims to describe the broad applications space covered by laser-based micro- and nanoprocessing techniques and the benefits offered by the use of lasers in micro-manufacturing processes. Given their non-lithographic nature, these processes are also referred to as laser direct-write and constitute some of the earliest demonstrations of 3D printing or additive manufacturing at the microscale. As this review will show, the use of lasers enables precise control of the various types of processing steps—from subtractive to additive—over a wide range of scales with an extensive materials palette. Overall, laser-based direct-write techniques offer multiple modes of operation including the removal (via ablative processes) and addition (via photopolymerization or printing) of most classes of materials using the same equipment in many cases. The versatility provided by these multi-function, multi-material and multi-scale laser micro-manufacturing processes cannot be matched by photolithography nor with other direct-write microfabrication techniques and offer unique opportunities for current and future 3D micro-manufacturing applications. (topical review)

Implementing the South African additive manufacturing technology roadmap - the role of an additive manufacturing centre of competence

Directory of Open Access Journals (Sweden)

Du Preez, Willie Bouwer

2015-08-01

Full Text Available The Rapid Product Development Association of South Africa (RAPDASA expressed the need for a national Additive Manufacturing Roadmap. Consequentially, the South African Department of Science and Technology commissioned the development of a South African Additive Manufacturing Technology Roadmap. This was intended to guide role-players in identifying business opportunities, addressing technology gaps, focusing development programmes, and informing investment decisions that would enable local companies and industry sectors to become global leaders in selected areas of additive manufacturing. The challenge remains now for South Africa to decide on an implementation approach that will maximize the impact in the shortest possible time. This article introduces the concept of a national Additive Manufacturing Centre of Competence (AMCoC as a primary implementation vehicle for the roadmap. The support of the current leading players in additive manufacturing in South Africa for such a centre of competence is shared and their key roles are indicated. A summary of the investments that the leading players have already made in the focus areas of the AMCoC over the past two decades is given as confirmation of their commitment towards the advancement of the additive manufacturing technology. An exposition is given of how the AMCoC could indeed become the primary initiative for achieving the agreed national goals on additive manufacturing. The conclusion is that investment by public and private institutions in an AMCoC would be the next step towards ensuring South Africa’s continued progress in the field.

An Analysis of the Operational Environments of Manufacturing Firms ...

African Journals Online (AJOL)

Our efforts in this research have been geared towards analyzing the operational environments of manufacturing firms in Aba, South-East, Nigeria. Specifically, the case study was Manufacturers Association of Nigeria (MAN), Abia chapter. Eight five percent of MAN‟s membership was studied. Percentages and test of ...

Implementation of hierarchical design for manufacture rules in manufacturing processes

OpenAIRE

Parvez, Masud

2008-01-01

In order to shorten the product development cycle time, minimise overall cost and smooth transition into production, early consideration of manufacturing processes is important. Design for Manufacture (DFM) is the practice of designing products with manufacturing issues using an intelligent system, which translates 3D solid models into manufacturable features. Many existing and potential applications, particularly in the field of manufacturing, require various aspects of features technology. ...

Sustainability Characterization for Additive Manufacturing.

Science.gov (United States)

Mani, Mahesh; Lyons, Kevin W; Gupta, S K

2014-01-01

Additive manufacturing (AM) has the potential to create geometrically complex parts that require a high degree of customization, using less material and producing less waste. Recent studies have shown that AM can be an economically viable option for use by the industry, yet there are some inherent challenges associated with AM for wider acceptance. The lack of standards in AM impedes its use for parts production since industries primarily depend on established standards in processes and material selection to ensure the consistency and quality. Inability to compare AM performance against traditional manufacturing methods can be a barrier for implementing AM processes. AM process sustainability has become a driver due to growing environmental concerns for manufacturing. This has reinforced the importance to understand and characterize AM processes for sustainability. Process characterization for sustainability will help close the gaps for comparing AM performance to traditional manufacturing methods. Based on a literature review, this paper first examines the potential environmental impacts of AM. A methodology for sustainability characterization of AM is then proposed to serve as a resource for the community to benchmark AM processes for sustainability. Next, research perspectives are discussed along with relevant standardization efforts.

Composites Manufacturing Education and Technology Facility Expedites Manufacturing Innovation

Energy Technology Data Exchange (ETDEWEB)

2017-01-01

The Composites Manufacturing Education and Technology facility (CoMET) at the National Wind Technology Center at the National Renewable Energy Laboratory (NREL) paves the way for innovative wind turbine components and accelerated manufacturing. Available for use by industry partners and university researchers, the 10,000-square-foot facility expands NREL's composite manufacturing research capabilities by enabling researchers to design, prototype, and test composite wind turbine blades and other components -- and then manufacture them onsite. Designed to work in conjunction with NREL's design, analysis, and structural testing capabilities, the CoMET facility expedites manufacturing innovation.

Manufacturing strategy issues in selected Indian manufacturing industry

Directory of Open Access Journals (Sweden)

Mahender Singh

2013-03-01

Full Text Available This paper presents some findings of Indian manufacturing sectors viz. automobile (especially two-wheeler, tractor and general manufacturing industry. Various manufacturing strategy issues such as competitive priorities, improvement activities, and performance measures, have been identified and assessed in Indian context. Sector wise comparison of competitive priorities, improvement activities i.e. advanced manufacturing technology (AMT, integrated information systems (IIS, and advanced management systems (AMS, and performance measure, is provided. Our results showed that most of the Indian companies are still emphasizing on quality. However, automobile sector has set to compete globally with high innovation rate, faster new product development, and continuous improvement. It is also observed that Indian companies are investing more in AMS as compared to IIS and AMT. Manufacturing competence index is also computed for each sector.

Virtual Manufacturing Techniques Designed and Applied to Manufacturing Activities in the Manufacturing Integration and Technology Branch

Science.gov (United States)

Shearrow, Charles A.

1999-01-01

One of the identified goals of EM3 is to implement virtual manufacturing by the time the year 2000 has ended. To realize this goal of a true virtual manufacturing enterprise the initial development of a machinability database and the infrastructure must be completed. This will consist of the containment of the existing EM-NET problems and developing machine, tooling, and common materials databases. To integrate the virtual manufacturing enterprise with normal day to day operations the development of a parallel virtual manufacturing machinability database, virtual manufacturing database, virtual manufacturing paradigm, implementation/integration procedure, and testable verification models must be constructed. Common and virtual machinability databases will include the four distinct areas of machine tools, available tooling, common machine tool loads, and a materials database. The machine tools database will include the machine envelope, special machine attachments, tooling capacity, location within NASA-JSC or with a contractor, and availability/scheduling. The tooling database will include available standard tooling, custom in-house tooling, tool properties, and availability. The common materials database will include materials thickness ranges, strengths, types, and their availability. The virtual manufacturing databases will consist of virtual machines and virtual tooling directly related to the common and machinability databases. The items to be completed are the design and construction of the machinability databases, virtual manufacturing paradigm for NASA-JSC, implementation timeline, VNC model of one bridge mill and troubleshoot existing software and hardware problems with EN4NET. The final step of this virtual manufacturing project will be to integrate other production sites into the databases bringing JSC's EM3 into a position of becoming a clearing house for NASA's digital manufacturing needs creating a true virtual manufacturing enterprise.

Semiconductor Manufacturing equipment introduction

International Nuclear Information System (INIS)

Im, Jong Sun

2001-02-01

This book deals with semiconductor manufacturing equipment. It is comprised of nine chapters, which are manufacturing process of semiconductor device, history of semiconductor manufacturing equipment, kinds and role of semiconductor manufacturing equipment, construction and method of semiconductor manufacturing equipment, introduction of various semiconductor manufacturing equipment, spots of semiconductor manufacturing, technical elements of semiconductor manufacturing equipment, road map of technology of semiconductor manufacturing equipment and semiconductor manufacturing equipment in the 21st century.

Advanced Manufacturing Technologies

Science.gov (United States)

Fikes, John

2016-01-01

Advanced Manufacturing Technologies (AMT) is developing and maturing innovative and advanced manufacturing technologies that will enable more capable and lower-cost spacecraft, launch vehicles and infrastructure to enable exploration missions. The technologies will utilize cutting edge materials and emerging capabilities including metallic processes, additive manufacturing, composites, and digital manufacturing. The AMT project supports the National Manufacturing Initiative involving collaboration with other government agencies.

Efficiency of manufacturing processes energy and ecological perspectives

CERN Document Server

Li, Wen

2015-01-01

 This monograph presents a reliable methodology for characterising the energy and eco-efficiency of unit manufacturing processes. The Specific Energy Consumption, SEC, will be identified as the key indicator for the energy efficiency of unit processes.  An empirical approach will be validated on different machine tools and manufacturing processes to depict the relationship between process parameters and energy consumptions. Statistical results and additional validation runs will corroborate the high level of accuracy in predicting the energy consumption. In relation to the eco-efficiency, the value and the associated environmental impacts of  manufacturing processes will also be discussed. The interrelationship between process parameters, process value and the associated environmental impact will be integrated in the evaluation of eco-efficiency. The book concludes with a further investigation of the results in order to develop strategies for further efficiency improvement. The target audience primarily co...

Industry 4.0 implies lean manufacturing: Research activities in industry 4.0 function as enablers for lean manufacturing

Directory of Open Access Journals (Sweden)

Adam Sanders

2016-09-01

Full Text Available Purpose: Lean Manufacturing is widely regarded as a potential methodology to improve productivity and decrease costs in manufacturing organisations. The success of lean manufacturing demands consistent and conscious efforts from the organisation, and has to overcome several hindrances. Industry 4.0 makes a factory smart by applying advanced information and communication systems and future-oriented technologies. This paper analyses the incompletely perceived link between Industry 4.0 and lean manufacturing, and investigates whether Industry 4.0 is capable of implementing lean. Executing Industry 4.0 is a cost-intensive operation, and is met with reluctance from several manufacturers. This research also provides an important insight into manufacturers’ dilemma as to whether they can commit into Industry 4.0, considering the investment required and unperceived benefits. Design/methodology/approach: Lean manufacturing is first defined and different dimensions of lean are presented. Then Industry 4.0 is defined followed by representing its current status in Germany. The barriers for implementation of lean are analysed from the perspective of integration of resources. Literatures associated with Industry 4.0 are studied and suitable solution principles are identified to solve the abovementioned barriers of implementing lean. Findings: It is identified that researches and publications in the field of Industry 4.0 held answers to overcome the barriers of implementation of lean manufacturing. These potential solution principles prove the hypothesis that Industry 4.0 is indeed capable of implementing lean. It uncovers the fact that committing into Industry 4.0 makes a factory lean besides being smart. Originality/value: Individual researches have been done in various technologies allied with Industry 4.0, but the potential to execute lean manufacturing was not completely perceived. This paper bridges the gap between these two realms, and identifies

Servitization in Danish Manufacturing Firms: A Strategy for Survival?

DEFF Research Database (Denmark)

Slepniov, Dmitrij; Wæhrens, Brian Vejrum; Johansen, John

2010-01-01

) and by many traditional manufacturers is perceived as a strategy for survival. On the basis of multiple cases of Danish companies, this paper discusses the main reasons and strategic implications of servitization. Furthermore, it outlines the strategies of how traditional manufacturers can recoup the desired...... level of return from the developments associated with servitization....

Acylinder and freeform optical manufacturing

Science.gov (United States)

Fess, Edward; Wolfs, Frank; DeFisher, Scott; Ross, James

2015-10-01

Aspheric cylinders have the ability to improve optical performance over standard cylindrical surfaces. Over the last several years there has also been development into the application and functionality of utilizing freeform surfaces to improve optical performance. Freeforms have the ability to not only improve image quality over a greater field of view, but can open up the design space of an optical system making it more compact. Freeform geometries, much like aspheric cylinders, may not have an axis of rotation to spin the optic about during manufacturing. This leads to costly fabrication processes and custom metrology set ups, which may inhibit their use. Over the last several years, OptiPro Systems has developed and optimized our eSX grinding, UFF and USF polishing, UltraSurf metrology, and ProSurf software programming technologies to make the processing of these complex geometries much easier and deterministic. In this paper we will discuss the challenges associated with manufacturing complex shapes like aspheric cylinders as well as freeform geometries, and how several technologies working together can overcome them. The technologies focus on metrology feedback to a grinding and polishing machine that is controlled through an iterative computer aided manufacturing software system. We will also present examples of these hard to manufacture shapes with results.

Development of Advanced Ceramic Manufacturing Technology; FINAL

International Nuclear Information System (INIS)

Pujari, V.K.

2001-01-01

Advanced structural ceramics are enabling materials for new transportation engine systems that have the potential for significantly reducing energy consumption and pollution in automobiles and heavy vehicles. Ceramic component reliability and performance have been demonstrated in previous U.S. DOE initiatives, but high manufacturing cost was recognized as a major barrier to commercialization. Norton Advanced Ceramics (NAC), a division of Saint-Gobain Industrial Ceramics, Inc. (SGIC), was selected to perform a major Advanced Ceramics Manufacturing Technology (ACMT) Program. The overall objectives of NAC's program were to design, develop, and demonstrate advanced manufacturing technology for the production of ceramic exhaust valves for diesel engines. The specific objectives were (1) to reduce the manufacturing cost by an order of magnitude, (2) to develop and demonstrate process capability and reproducibility, and (3) to validate ceramic valve performance, durability, and reliability. I n order to achieve these objectives, NAC, a leading U.S. advanced ceramics component manufacturer, assembled a multidisciplinary, vertically integrated team. This team included: a major diesel engine builder, Detroit Diesel Corporation (DDC); a corporate ceramics research division, SGIC's Northboro R and D Center; intelligent processing system developers, BDM Federal/MATSYS; a furnace equipment company, Centorr/Vacuum Industries; a sintering expert, Wittmer Consultants; a production OEM, Deco-Grand; a wheel manufacturer and grinding operation developer, Norton Company's Higgins Grinding Technology Center (HGTC); a ceramic machine shop, Chand Kare Technical Ceramics; and a manufacturing cost consultant, IBIS Associates. The program was divided into four major tasks: Component Design and Specification, Component Manufacturing Technology Development, Inspection and Testing, and Process Demonstration

Historical Financial Data - Domestic Automobile Manufacturers

Science.gov (United States)

1979-01-01

A historical financial data base was developed for the four major U.S. automobile manufacturers, focusing on the specific operations associated with production and marketing of automobiles and light trucks. The years subject to analysis were 1967-197...

Micro-manufacturing: design and manufacturing of micro-products

National Research Council Canada - National Science Library

Koç, Muammer; Özel, Tuğrul

2011-01-01

.... After addressing the fundamentals and non-metallic-based micro-manufacturing processes in the semiconductor industry, it goes on to address specific metallic-based micro-manufacturing processes...

Design and application of reconfigurable manufacturing systems in agile mass customization manufacturing environment.

CSIR Research Space (South Africa)

Xing, B

2007-05-01

Full Text Available processes. Many manufacturing techniques are based on the principles of Flexible Manufacturing and Dedicated Manufacturing for mass production. Reconfigurable Manufacturing System, (RMS), is a manufacturing system that can provide for Agile Manufacturing...

Regulatory Perspectives on Continuous Pharmaceutical Manufacturing: Moving From Theory to Practice: September 26-27, 2016, International Symposium on the Continuous Manufacturing of Pharmaceuticals.

Science.gov (United States)

Nasr, Moheb M; Krumme, Markus; Matsuda, Yoshihiro; Trout, Bernhardt L; Badman, Clive; Mascia, Salvatore; Cooney, Charles L; Jensen, Keith D; Florence, Alastair; Johnston, Craig; Konstantinov, Konstantin; Lee, Sau L

2017-11-01

Continuous manufacturing plays a key role in enabling the modernization of pharmaceutical manufacturing. The fate of this emerging technology will rely, in large part, on the regulatory implementation of this novel technology. This paper, which is based on the 2nd International Symposium on the Continuous Manufacturing of Pharmaceuticals, describes not only the advances that have taken place since the first International Symposium on Continuous Manufacturing of Pharmaceuticals in 2014, but the regulatory landscape that exists today. Key regulatory concepts including quality risk management, batch definition, control strategy, process monitoring and control, real-time release testing, data processing and management, and process validation/verification are outlined. Support from regulatory agencies, particularly in the form of the harmonization of regulatory expectations, will be crucial to the successful implementation of continuous manufacturing. Collaborative efforts, among academia, industry, and regulatory agencies, are the optimal solution for ensuring a solid future for this promising manufacturing technology. Copyright © 2017 American Pharmacists Association®. All rights reserved.

Advances in solid dosage form manufacturing technology.

Science.gov (United States)

Andrews, Gavin P

2007-12-15

Currently, the pharmaceutical and healthcare industries are moving through a period of unparalleled change. Major multinational pharmaceutical companies are restructuring, consolidating, merging and more importantly critically assessing their competitiveness to ensure constant growth in an ever-more demanding market where the cost of developing novel products is continuously increasing. The pharmaceutical manufacturing processes currently in existence for the production of solid oral dosage forms are associated with significant disadvantages and in many instances provide many processing problems. Therefore, it is well accepted that there is an increasing need for alternative processes to dramatically improve powder processing, and more importantly to ensure that acceptable, reproducible solid dosage forms can be manufactured. Consequently, pharmaceutical companies are beginning to invest in innovative processes capable of producing solid dosage forms that better meet the needs of the patient while providing efficient manufacturing operations. This article discusses two emerging solid dosage form manufacturing technologies, namely hot-melt extrusion and fluidized hot-melt granulation.

Cloud Manufacturing Service Paradigm for Group Manufacturing Companies

Directory of Open Access Journals (Sweden)

Jingtao Zhou

2014-07-01

Full Text Available The continuous refinement of specialization requires that the group manufacturing company must be constantly focused on how to concentrate its core resources in special sphere to form its core competitive advantage. However, the resources in enterprise group are usually distributed in different subsidiary companies, which means they cannot be fully used, constraining the competition and development of the enterprise. Conducted as a response to a need for cloud manufacturing studies, systematic and detailed studies on cloud manufacturing schema for group companies are carried out in this paper. A new hybrid private clouds paradigm is proposed to meet the requirements of aggregation and centralized use of heterogeneous resources and business units distributed in different subsidiary companies. After the introduction of the cloud manufacturing paradigm for enterprise group and its architecture, this paper presents a derivation from the abstraction of paradigm and framework to the application of a practical evaluative working mechanism. In short, the paradigm establishes an effective working mechanism to translate collaborative business process composed by the activities into cloud manufacturing process composed by services so as to create a foundation resulting in mature traditional project monitoring and scheduling technologies being able to be used in cloud manufacturing project management.

Manufacturing and Security Challenges in 3D Printing

Science.gov (United States)

Zeltmann, Steven Eric; Gupta, Nikhil; Tsoutsos, Nektarios Georgios; Maniatakos, Michail; Rajendran, Jeyavijayan; Karri, Ramesh

2016-07-01

As the manufacturing time, quality, and cost associated with additive manufacturing (AM) continue to improve, more and more businesses and consumers are adopting this technology. Some of the key benefits of AM include customizing products, localizing production and reducing logistics. Due to these and numerous other benefits, AM is enabling a globally distributed manufacturing process and supply chain spanning multiple parties, and hence raises concerns about the reliability of the manufactured product. In this work, we first present a brief overview of the potential risks that exist in the cyber-physical environment of additive manufacturing. We then evaluate the risks posed by two different classes of modifications to the AM process which are representative of the challenges that are unique to AM. The risks posed are examined through mechanical testing of objects with altered printing orientation and fine internal defects. Finite element analysis and ultrasonic inspection are also used to demonstrate the potential for decreased performance and for evading detection. The results highlight several scenarios, intentional or unintentional, that can affect the product quality and pose security challenges for the additive manufacturing supply chain.

Manufacturing Renaissance : Return of manufacturing to western countries

OpenAIRE

Kianian, Babak; Larsson, Tobias; Tavassoli, Mohammad

2013-01-01

This chapter argues that the location of manufacturing is gradually shifting to the west again, exemplifying the ‘manufacturing renaissance’. Such a claim is based on the recent observed trend and the discussion is contextualized within the established theory that has been able to explain the location of manufacturing, that is, the product life cycle (PLC) model. Then the chapter identifies and discusses the four main drivers of this new phenomenon: (i) rising wage levels in emerging economie...

Measuring Manufacturing Innovativeness

DEFF Research Database (Denmark)

Blichfeldt, Henrik; Knudsen, Mette Præst

2017-01-01

Globalization and customization increases the pressure on manufacturing companies, and the ability to provide innovativeness is a potential source of competitive advantage. This paper positions the manufacturing entity in the innovation process, and investigates the relation between innovation vers...... technology and organizational concepts. Based on Danish survey data from the European Manufacturing Survey (EMS-2015) this paper finds that there is a relation between innovative companies, and their level of technology and use of organizational concepts. Technology and organizational concepts act...... as manufacturing levers to support the manufacturing and production system to provide innovativeness. The managerial implication lies in building manufacturing capabilities to support the innovative process, by standardization, optimization and creating stability in combination with automation and advanced...

Robot skills for manufacturing

DEFF Research Database (Denmark)

Pedersen, Mikkel Rath; Nalpantidis, Lazaros; Andersen, Rasmus Skovgaard

2016-01-01

-asserting robot skills for manufacturing. We show how a relatively small set of skills are derived from current factory worker instructions, and how these can be transferred to industrial mobile manipulators. General robot skills can not only be implemented on these robots, but also be intuitively concatenated...... products are introduced by manufacturers. In order to compete on global markets, the factories of tomorrow need complete production lines, including automation technologies that can effortlessly be reconfigured or repurposed, when the need arises. In this paper we present the concept of general, self...... in running production facilities at an industrial partner. It follows from these experiments that the use of robot skills, and associated task-level programming framework, is a viable solution to introducing robots that can intuitively and on the fly be programmed to perform new tasks by factory workers....

Cloud manufacturing distributed computing technologies for global and sustainable manufacturing

CERN Document Server

Mehnen, Jörn

2013-01-01

Global networks, which are the primary pillars of the modern manufacturing industry and supply chains, can only cope with the new challenges, requirements and demands when supported by new computing and Internet-based technologies. Cloud Manufacturing: Distributed Computing Technologies for Global and Sustainable Manufacturing introduces a new paradigm for scalable service-oriented sustainable and globally distributed manufacturing systems.   The eleven chapters in this book provide an updated overview of the latest technological development and applications in relevant research areas.  Following an introduction to the essential features of Cloud Computing, chapters cover a range of methods and applications such as the factors that actually affect adoption of the Cloud Computing technology in manufacturing companies and new geometrical simplification method to stream 3-Dimensional design and manufacturing data via the Internet. This is further supported case studies and real life data for Waste Electrical ...

Reconfigurable manufacturing system for agile mass customization manufacturing

CSIR Research Space (South Africa)

Xing, B

2006-07-01

Full Text Available Manufacturing companies are facing three challenges: low cost production of product, high quality standard and rapid responsiveness to customer requirements. These three goals are equally important for the manufacturing companies who want...

Manufacturing Initiative

Data.gov (United States)

National Aeronautics and Space Administration — The Advanced Manufacturing Technologies (AMT) Project supports multiple activities within the Administration's National Manufacturing Initiative. A key component of...

Just-in-time Design and Additive Manufacture of Patient-specific Medical Implants

Science.gov (United States)

Shidid, Darpan; Leary, Martin; Choong, Peter; Brandt, Milan

Recent advances in medical imaging and manufacturing science have enabled the design and production of complex, patient-specific orthopaedic implants. Additive Manufacture (AM) generates three-dimensional structures layer by layer, and is not subject to the constraints associated with traditional manufacturing methods. AM provides significant opportunities for the design of novel geometries and complex lattice structures with enhanced functional performance. However, the design and manufacture of patient-specific AM implant structures requires unique expertise in handling various optimization platforms. Furthermore, the design process for complex structures is computationally intensive. The primary aim of this research is to enable the just-in-time customisation of AM prosthesis; whereby AM implant design and manufacture be completed within the time constraints of a single surgical procedure, while minimising prosthesis mass and optimising the lattice structure to match the stiffness of the surrounding bone tissue. In this research, a design approach using raw CT scan data is applied to the AM manufacture of femoral prosthesis. Using the proposed just-in-time concept, the mass of the prosthesis was rapidly designed and manufactured while satisfying the associated structural requirements. Compressive testing of lattice structures manufactured using proposed method shows that the load carrying capacity of the resected composite bone can be recovered by up to 85% and the compressive stiffness of the AM prosthesis is statistically indistinguishable from the stiffness of the initial bone.

Life-cycle inventory of manufacturing hardwood lumber in Southeastern US

Science.gov (United States)

Richard D. Bergman; Scott A. Bowe

2012-01-01

Environmental impacts associated with the building industry have become of increasing importance. Materials and energy consumed during manufacture of building materials such as lumber affect a building’s environmental performance. This study determined environmental impacts of manufacturing hardwood lumber in the southeastern US using the life-cycle inventory method....

Technological assessment of local manufacturers for wind turbine blade manufacturing in Pakistan

Science.gov (United States)

Mahmood, Khurram; Haroon, General

2012-11-01

Composite materials manufacturing industry is one of the world's hi-tech industry. Manufacturing of wind turbine blades is one of the specialized fields requiring high degree of precision and composite manufacturing techniques. This paper identifies the industries specializing in the composite manufacturing and is able to manufacture wind turbines blades in Pakistan. In the second phase, their technology readiness level is determined, based on some factors and then a readiness level are assigned to them. The assigned technology readiness level will depict the absorptive capacity of each manufacturing unit and its capability to take on such projects. The individual readiness level of manufacturing unit will then be used to establish combined technology readiness level of Pakistan particularly for wind turbine blades manufacturing. The composite manufacturing industry provides many spin offs and a diverse range of products can be manufactured using this facility. This research will be helpful to categorize the strong points and flaws of local industry for the gap analysis. It can also be used as a prerequisite study before the evaluation of technologies and specialties to improve the industry of the country for the most favorable results. This will form a basic data base which can be used for the decision making related to transfer of technology, training of local skilled workers and general up-gradation of the local manufacturing units.

Reducing of Manufacturing Lead Time by Implementation of Lean Manufacturing Principles

Directory of Open Access Journals (Sweden)

Hussein Salem Ketan

2015-08-01

Full Text Available Many organizations today are interesting to implementing lean manufacturing principles that should enable them to eliminating the wastes to reducing a manufacturing lead time. This paper concentrates on increasing the competitive level of the company in globalization markets and improving of the productivity by reducing the manufacturing lead time. This will be by using the main tool of lean manufacturing which is value stream mapping (VSM to identifying all the activities of manufacturing process (value and non-value added activities to reducing elimination of wastes (non-value added activities by converting a manufacturing system to pull instead of push by applying some of pull system strategies as kanban and first on first out lane (FIFO. ARENA software is used to simulate the current and future state. This work is executed in the state company for electrical industries in Baghdad. The obtained results of the application showed that implementation of lean principles helped on reducing of a manufacturing lead time by 33%.

An investigation into standards in sustainable design and manufacture

OpenAIRE

Plant, AVC; Harrison, DJ; Griffiths, BJ; Lam, B

2009-01-01

This paper reports upon the application of standards to reduce the negative environmental impacts of manufacturing through product lifecycle planning and closed loop production. By eliminating waste and retaining the energy embodied within materials and components, manufacturing can become more sustainable from both ecological and financial perspectives. Energy consumption and the associated carbon pollution can thus be minimised. Environmental Management System implementation is also cons...

Tribology in Manufacturing Technology

CERN Document Server

2013-01-01

The present book aims to provide research advances on tribology in manufacturing technology for modern industry. This book can be used as a research book for final undergraduate engineering course (for example, mechanical, manufacturing, materials, etc) or as a subject on manufacturing at the postgraduate level. Also, this book can serve as a useful reference for academics, manufacturing and tribology researchers, mechanical, mechanical, manufacturing and materials engineers, professionals in related industries with manufacturing and tribology.

Demographic, health-related, and work-related factors associated with body mass index and body fat percentage among workers at six Connecticut manufacturing companies across different age groups: a cohort study.

Science.gov (United States)

Garza, Jennifer L; Dugan, Alicia G; Faghri, Pouran D; Gorin, Amy A; Huedo-Medina, Tania B; Kenny, Anne M; Cherniack, Martin G; Cavallari, Jennifer M

2015-01-01

Effective workplace interventions that consider the multifactorial nature of obesity are needed to reduce and prevent obesity among adults. Furthermore, the factors associated with obesity may differ for workers across age groups. Therefore, the objective of this study was to identify demographic, health-related, and work-related factors associated with baseline and changes in body mass index (BMI) and body fat percentage (BFP) and among Connecticut manufacturing workers acrossage groups. BMI and BFPof 758 workers from six Connecticut manufacturing companies were objectively measuredat two time points approximately 36 months apart. Demographic, health-related, and work-related factors wereassessed via questionnaire. All variables were included in linear regression models to identify factors associated with baseline and changes in BMI and BFP for workers in 3 age groups: 55 years (28 %). There were differences in baseline and changes in BMI and BFP among manufacturing workers across age groups. Being interested in changing weight was significantly (p gender (BMI p = 0.04), female gender (BFP p gender (BMI p = 0.02), female gender (BFP p gender (BFP p 55 year age category. Few factors were associated with change in BMI or BFP across any age category. Among manufacturing workers, we identified associations between individual, health-related, and work-related factors and baseline BMIand BFP that differed by age. Such results support the use of strategies tailored to the challenges faced by workers in specific age groups rather than adopting a one size fits all approach. Effective interventions should consider a full range of individual, health-related, and work-related factors. More work must be done to identify factors or strategies associated with changes in obesity over time.

Advanced Blade Manufacturing Project - Final Report

Energy Technology Data Exchange (ETDEWEB)

POORE, ROBERT Z.

1999-08-01

The original scope of the project was to research improvements to the processes and materials used in the manufacture of wood-epoxy blades, conduct tests to qualify any new material or processes for use in blade design and subsequently build and test six blades using the improved processes and materials. In particular, ABM was interested in reducing blade cost and improving quality. In addition, ABM needed to find a replacement material for the mature Douglas fir used in the manufacturing process. The use of mature Douglas fir is commercially unacceptable because of its limited supply and environmental concerns associated with the use of mature timber. Unfortunately, the bankruptcy of FloWind in June 1997 and a dramatic reduction in AWT sales made it impossible for ABM to complete the full scope of work. However, sufficient research and testing were completed to identify several promising changes in the blade manufacturing process and develop a preliminary design incorporating these changes.

Competitive manufacturing strategies for the manufacturing industries in Turkey

OpenAIRE

Ulusoy, Gündüz; Ulusoy, Gunduz

2003-01-01

In this study, results of the research into competitive manufacturing strategies of companies in four different sector studies covering 82 companies from the electronics, cement, automotive manufacturers, and appliances part and component suppliers in Turkey are presented. The data used in the study are gathered by conducting four sector surveys in 1997 and 1998 using a questionnaire supported by some follow-up interviews and site visits. A competitive manufacturing strategy is represented he...

Modular mechatronic control of reconfigurable manufacturing system for mass customization manufacturing

CSIR Research Space (South Africa)

Xing, B

2007-01-01

Full Text Available Manufacturing companies are faced with the challenge of unpredictable, high frequency market changes in both local and international markets. There is a need for greater, more effective responsiveness by manufacturers to change their manufacturing...

Test Methods for Robot Agility in Manufacturing.

Science.gov (United States)

Downs, Anthony; Harrison, William; Schlenoff, Craig

2016-01-01

The paper aims to define and describe test methods and metrics to assess industrial robot system agility in both simulation and in reality. The paper describes test methods and associated quantitative and qualitative metrics for assessing robot system efficiency and effectiveness which can then be used for the assessment of system agility. The paper describes how the test methods were implemented in a simulation environment and real world environment. It also shows how the metrics are measured and assessed as they would be in a future competition. The test methods described in this paper will push forward the state of the art in software agility for manufacturing robots, allowing small and medium manufacturers to better utilize robotic systems. The paper fulfills the identified need for standard test methods to measure and allow for improvement in software agility for manufacturing robots.

Micro Manufacturing

DEFF Research Database (Denmark)

Hansen, Hans Nørgaard

2003-01-01

Manufacturing deals with systems that include products, processes, materials and production systems. These systems have functional requirements, constraints, design parameters and process variables. They must be decomposed in a systematic manner to achieve the best possible system performance....... If a micro manufacturing system isn’t designed rationally and correctly, it will be high-cost, unreliable, and not robust. For micro products and systems it is a continuously increasing challenge to create the operational basis for an industrial production. As the products through product development...... processes are made applicable to a large number of customers, the pressure in regard to developing production technologies that make it possible to produce the products at a reasonable price and in large numbers is growing. The micro/nano manufacturing programme at the Department of Manufacturing...

Exploring manufacturing competencies of a two wheeler manufacturing unit

Science.gov (United States)

Deep Singh, Chandan; Singh Khamba, Jaimal; Singh, Rajdeep; Singh, Navdeep

2014-07-01

The two wheeler industry of India is one of the most dependable industries as every person has at least a two wheeler with him, if not any four wheeler. Earlier there were scooters like Bajaj Chetak, Priya but with evolution of motorcycles like splendor, splendor+, etc. the scooter market started declining but with arrival of gearless scooters like Honda Activa, Scooty Pep, etc. the market place has become increasingly competitive in recent time and industries are facing tough test of improving products and thus market share. The competitiveness among industries is an important issue. Competency development is a vital tool to enhance the competitiveness of industries. Based, on aggregate performance of a firm, it comprehensively explores the varying importance of manufacturing competencies and drives of industrial competitiveness. Hence by, exploring the manufacturing competencies of a two wheeler industry, one can reflect the competitiveness of two wheeler manufacturing industry as a whole. This study presents various factors of manufacturing competencies affecting industrial competitiveness as the significance of these competencies is increasing day by day in two wheeler manufacturing industry.

Exploring manufacturing competencies of a two wheeler manufacturing unit

International Nuclear Information System (INIS)

Singh, Chandan Deep; Khamba, Jaimal Singh; Singh, Rajdeep; Singh, Navdeep

2014-01-01

The two wheeler industry of India is one of the most dependable industries as every person has at least a two wheeler with him, if not any four wheeler. Earlier there were scooters like Bajaj Chetak, Priya but with evolution of motorcycles like splendor, splendor+, etc. the scooter market started declining but with arrival of gearless scooters like Honda Activa, Scooty Pep, etc. the market place has become increasingly competitive in recent time and industries are facing tough test of improving products and thus market share. The competitiveness among industries is an important issue. Competency development is a vital tool to enhance the competitiveness of industries. Based, on aggregate performance of a firm, it comprehensively explores the varying importance of manufacturing competencies and drives of industrial competitiveness. Hence by, exploring the manufacturing competencies of a two wheeler industry, one can reflect the competitiveness of two wheeler manufacturing industry as a whole. This study presents various factors of manufacturing competencies affecting industrial competitiveness as the significance of these competencies is increasing day by day in two wheeler manufacturing industry

Development of novel IVD assays: a manufacturer's perspective.

Science.gov (United States)

Metcalfe, Thomas A

2010-01-01

IVD manufacturers are heavily reliant on novel IVD assays to fuel their growth and drive innovation within the industry. They represent a key part of the IVD industry's value proposition to customers and the healthcare industry in general, driving product differentiation, helping to create demand for new systems and generating incremental revenue. However, the discovery of novel biomarkers and their qualification for a specific clinical purpose is a high risk undertaking and the large, risky investments associated with doing this on a large scale are incompatible with IVD manufacturer's business models. This article describes the sources of novel IVD assays, the processes for discovering and qualifying novel assays and the reliance of IVD manufacturers on collaborations and in-licensing to source new IVD assays for their platforms.

Antimicrobial Peptides in Biomedical Device Manufacturing

Science.gov (United States)

Riool, Martijn; de Breij, Anna; Drijfhout, Jan W.; Nibbering, Peter H.; Zaat, Sebastian A. J.

2017-08-01

Over the past decades the use of medical devices, such as catheters, artificial heart valves, prosthetic joints and other implants, has grown significantly. Despite continuous improvements in device design, surgical procedures and wound care, biomaterial-associated infections (BAI) are still a major problem in modern medicine. Conventional antibiotic treatment often fails due to the low levels of antibiotic at the site of infection. The presence of biofilms on the biomaterial and/or the multidrug-resistant phenotype of the bacteria further impair the efficacy of antibiotic treatment. Removal of the biomaterial is then the last option to control the infection. Clearly, there is a pressing need for alternative strategies to prevent and treat BAI. Synthetic antimicrobial peptides (AMPs) are considered promising candidates as they are active against a broad spectrum of (antibiotic-resistant) planktonic bacteria and biofilms. Moreover, bacteria are less likely to develop resistance to these rapidly-acting peptides. In this review we highlight the four main strategies, three of which applying AMPs, in biomedical device manufacturing to prevent BAI. The first involves modification of the physicochemical characteristics of the surface of implants. Immobilization of AMPs on surfaces of medical devices with a variety of chemical techniques is essential in the second strategy. The main disadvantage of these two strategies relates to the limited antibacterial effect in the tissue surrounding the implant. This limitation is addressed by the third strategy that releases AMPs from a coating in a controlled fashion. Lastly, AMPs can be integrated in the design and manufacturing of additively manufactured / 3D-printed implants, owing to the physicochemical characteristics of the implant material and the versatile manufacturing technologies compatible with antimicrobials incorporation. These novel technologies utilizing AMPs will contribute to development of novel and safe

Antimicrobial Peptides in Biomedical Device Manufacturing

Directory of Open Access Journals (Sweden)

Martijn Riool

2017-08-01

Full Text Available Over the past decades the use of medical devices, such as catheters, artificial heart valves, prosthetic joints, and other implants, has grown significantly. Despite continuous improvements in device design, surgical procedures, and wound care, biomaterial-associated infections (BAI are still a major problem in modern medicine. Conventional antibiotic treatment often fails due to the low levels of antibiotic at the site of infection. The presence of biofilms on the biomaterial and/or the multidrug-resistant phenotype of the bacteria further impair the efficacy of antibiotic treatment. Removal of the biomaterial is then the last option to control the infection. Clearly, there is a pressing need for alternative strategies to prevent and treat BAI. Synthetic antimicrobial peptides (AMPs are considered promising candidates as they are active against a broad spectrum of (antibiotic-resistant planktonic bacteria and biofilms. Moreover, bacteria are less likely to develop resistance to these rapidly-acting peptides. In this review we highlight the four main strategies, three of which applying AMPs, in biomedical device manufacturing to prevent BAI. The first involves modification of the physicochemical characteristics of the surface of implants. Immobilization of AMPs on surfaces of medical devices with a variety of chemical techniques is essential in the second strategy. The main disadvantage of these two strategies relates to the limited antibacterial effect in the tissue surrounding the implant. This limitation is addressed by the third strategy that releases AMPs from a coating in a controlled fashion. Lastly, AMPs can be integrated in the design and manufacturing of additively manufactured/3D-printed implants, owing to the physicochemical characteristics of the implant material and the versatile manufacturing technologies compatible with antimicrobials incorporation. These novel technologies utilizing AMPs will contribute to development of novel

Additive Design and Manufacturing of Jet Engine Parts

Directory of Open Access Journals (Sweden)

Pinlian Han

2017-10-01

Full Text Available The additive design (AD and additive manufacturing (AM of jet engine parts will revolutionize the traditional aerospace industry. The unique characteristics of AM, such as gradient materials and micro-structures, have opened up a new direction in jet engine design and manufacturing. Engineers have been liberated from many constraints associated with traditional methodologies and technologies. One of the most significant features of the AM process is that it can ensure the consistency of parts because it starts from point(s, continues to line(s and layer(s, and ends with the competed part. Collaboration between design and manufacturing is the key to success in fields including aerodynamics, thermodynamics, structural integration, heat transfer, material development, and machining. Engineers must change the way they design a part, as they shift from the traditional method of “subtracting material” to the new method of “adding material” in order to manufacture a part. AD is not the same as designing for AM. A new method and new tools are required to assist with this new way of designing and manufacturing. This paper discusses in detail what is required in AD and AM, and how current problems can be solved.

Manufacturing engineering and technology

CERN Document Server

Kalpakjian, Serope; Vijai Sekar, K S

2014-01-01

For courses in manufacturing processes at two- or four-year schools. An up-to-date text that provides a solid background in manufacturing processes. Manufacturing Engineering and Technology, SI Edition, 7e, presents a mostly qualitative description of the science, technology, and practice of manufacturing. This includes detailed descriptions of manufacturing processes and the manufacturing enterprise that will help introduce students to important concepts. With a total of 120 examples and case studies, up-to-date and comprehensive coverage of all topics, and superior two-color graphics, this text provides a solid background for manufacturing students and serves as a valuable reference text for professionals. Teaching and Learning Experience To provide a better teaching and learning experience, for both instructors and students, this program will: * Apply Theory and/or Research: An excellent overview of manufacturing conceptswith a balance of relevant fundamentals and real-world practices. * Engage Students: E...

NASA's National Center for Advanced Manufacturing

Science.gov (United States)

Vickers, John

2003-01-01

, Tennessee Technological University, Texas A&M University, and Virginia Polytechnic Institute and State University provided wide-ranging engineering research, new degree/curriculum programs, and a web-based lecture series. NCAM has fostered an important presence and leadership role within the national manufacturing community. Its progressive influence can be seen in government, industry and academia, and in national associations, professional organizations, conferences, workshops, and forums.

Smart Manufacturing.

Science.gov (United States)

Davis, Jim; Edgar, Thomas; Graybill, Robert; Korambath, Prakashan; Schott, Brian; Swink, Denise; Wang, Jianwu; Wetzel, Jim

2015-01-01

Historic manufacturing enterprises based on vertically optimized companies, practices, market share, and competitiveness are giving way to enterprises that are responsive across an entire value chain to demand dynamic markets and customized product value adds; increased expectations for environmental sustainability, reduced energy usage, and zero incidents; and faster technology and product adoption. Agile innovation and manufacturing combined with radically increased productivity become engines for competitiveness and reinvestment, not simply for decreased cost. A focus on agility, productivity, energy, and environmental sustainability produces opportunities that are far beyond reducing market volatility. Agility directly impacts innovation, time-to-market, and faster, broader exploration of the trade space. These changes, the forces driving them, and new network-based information technologies offering unprecedented insights and analysis are motivating the advent of smart manufacturing and new information technology infrastructure for manufacturing.

Case study of lean manufacturing application in a die casting manufacturing company

Science.gov (United States)

Ching, Ng Tan; Hoe, Clarence Chan Kok; Hong, Tang Sai; Ghobakhloo, Morteza; Pin, Chen Kah

2015-05-01

The case study of lean manufacturing aims to study the application of lean manufacturing in a die casting manufacturing company located in Pulau Penang, Malaysia. This case study describes mainly about the important concepts and applications of lean manufacturing which could gradually help the company in increasing the profit by studying and analyzing their current manufacturing process and company culture. Many approaches of lean manufacturing are studied in this project which includes: 5S housekeeping, Kaizen, and Takt Time. Besides, the lean tools mentioned, quality tool such as the House of Quality is being used as an analysis tool to continuously improve the product quality. In short, the existing lean culture in the company is studied and analyzed, with recommendations written at the end of this paper.

China and the Manufacturing Exports of Other Developing Countries

OpenAIRE

Gordon H. Hanson; Raymond Robertson

2008-01-01

In this paper, we examine the impact of China's growth on developing countries that specialize in manufacturing. Over 2000-2005, manufacturing accounted for 32% of China's GDP and 89% of its merchandise exports, making it more specialized in the sector than any other large developing economy. Using the gravity model of trade, we decompose bilateral trade into components associated with demand conditions in importing countries, supply conditions in exporting countries, and bilateral trade cost...

Method for automatically evaluating a transition from a batch manufacturing technique to a lean manufacturing technique

Science.gov (United States)

Ivezic, Nenad; Potok, Thomas E.

2003-09-30

A method for automatically evaluating a manufacturing technique comprises the steps of: receiving from a user manufacturing process step parameters characterizing a manufacturing process; accepting from the user a selection for an analysis of a particular lean manufacturing technique; automatically compiling process step data for each process step in the manufacturing process; automatically calculating process metrics from a summation of the compiled process step data for each process step; and, presenting the automatically calculated process metrics to the user. A method for evaluating a transition from a batch manufacturing technique to a lean manufacturing technique can comprise the steps of: collecting manufacturing process step characterization parameters; selecting a lean manufacturing technique for analysis; communicating the selected lean manufacturing technique and the manufacturing process step characterization parameters to an automatic manufacturing technique evaluation engine having a mathematical model for generating manufacturing technique evaluation data; and, using the lean manufacturing technique evaluation data to determine whether to transition from an existing manufacturing technique to the selected lean manufacturing technique.

Experience in the manufacture of nuclear equipment in India

International Nuclear Information System (INIS)

Challappa, S.; Murthy, G.S.K.; Mehta, S.K.; Kakodkar, A.; Natarajan, A.

1977-01-01

Department of Atomic Energy with its programme for achieving self-sufficiency was involved in engineering, manufacture, inspection, performance testing and quality surveillance of major precision and critical equipment such as reactor vessels, shields, fuelling machines, coolant channel components etc. etc. high pressure equipment for Heavy Water Plants, specialized components for Fuel Complex, major equipment for Cyclotron Project and various research projects. These had to be manufactured at various shops in the country depending upon the availability of machines. The relative importance of various important parameters associated with the manufacture of this equipment were assessed in a separate R and D programme. This has helped in re-designing in some areas to suit the manufacture under Indian conditions. Assessment of any marginal variations that take place during manufacture was also possible because of the availability of data of this kind. Critical components and equipment are tested for their performance under simulated conditions before shipments. B.A.R.C. has contributed immensely in achieving the self-sufficiency and also for designs for future plants

Cloud manufacturing: a service-oriented manufacturing paradigm. A review paper

Directory of Open Access Journals (Sweden)

Siderska Julia

2018-03-01

Full Text Available This paper introduces cloud manufacturing (CMfg as a new manufacturing paradigm that joins the emerging technologies – such as the Internet of Things, cloud computing, and service-oriented technologies – for solving complex problems in manufacturing applications and performing large-scale collaborative manufacturing. Using scientific publications indexed in Scopus database during the period 2012–2017, the concept and fundamentals of CMfg are presented and discussed given the results of the most recent research. While focusing on the current state of the art, the recent research trends within CMfg concept were also identified. The review involved the methods of bibliometric analysis and network analysis. A prototype of CMfg and the existing related work conducted by various researchers are presented, and the map of co-occurrence is introduced to indicate the most commonly occurring issues related to the “cloud manufacturing” term. The VOSviewer software was used for this purpose. Finally, cloud-based manufacturing areas for further research are identified.

Business integration between manufacturing and transport-logistics firms

DEFF Research Database (Denmark)

Mortensen, Ole; Lemoine, Olga W.

electronically through EDI. The current business integration practices are primarily restricted to some sub-processes in three key SC processes: Customer service management, order fulfillment and backwards logistics. In the future the manufacturers want a better integration with the TLSPs, but at the same time......Purpose - This paper analyses how manufacturers and transport-logistics service providers (TLSPs) work together and integrate their business processes. The information technologies used to support the integration, the processes currently integrated, and the expected future integration, are searched......, manufacturers would like to have the freedom of breaking the relationship, if the party does not fulfill the requisites and expectations. The future developments associated to the "commoditization" of TLSPs' services would reinforce this trend. Originality/value - This research has shed light on a relatively...

Achieving continuous manufacturing: technologies and approaches for synthesis, workup, and isolation of drug substance. May 20-21, 2014 Continuous Manufacturing Symposium.

Science.gov (United States)

Baxendale, Ian R; Braatz, Richard D; Hodnett, Benjamin K; Jensen, Klavs F; Johnson, Martin D; Sharratt, Paul; Sherlock, Jon-Paul; Florence, Alastair J

2015-03-01

This whitepaper highlights current challenges and opportunities associated with continuous synthesis, workup, and crystallization of active pharmaceutical ingredients (drug substances). We describe the technologies and requirements at each stage and emphasize the different considerations for developing continuous processes compared with batch. In addition to the specific sequence of operations required to deliver the necessary chemical and physical transformations for continuous drug substance manufacture, consideration is also given to how adoption of continuous technologies may impact different manufacturing stages in development from discovery, process development, through scale-up and into full scale production. The impact of continuous manufacture on drug substance quality and the associated challenges for control and for process safety are also emphasized. In addition to the technology and operational considerations necessary for the adoption of continuous manufacturing (CM), this whitepaper also addresses the cultural, as well as skills and training, challenges that will need to be met by support from organizations in order to accommodate the new work flows. Specific action items for industry leaders are: Develop flow chemistry toolboxes, exploiting the advantages of flow processing and including highly selective chemistries that allow use of simple and effective continuous workup technologies. Availability of modular or plug and play type equipment especially for workup to assist in straightforward deployment in the laboratory. As with learning from other industries, standardization is highly desirable and will require cooperation across industry and academia to develop and implement. Implement and exploit process analytical technologies (PAT) for real-time dynamic control of continuous processes. Develop modeling and simulation techniques to support continuous process development and control. Progress is required in multiphase systems such as

Improving Project Manufacturing Coordination

Directory of Open Access Journals (Sweden)

Korpivaara Ville

2014-09-01

Full Text Available The objective of this research is to develop firms’ project manufacturing coordination. The development will be made by centralizing the manufacturing information flows in one system. To be able to centralize information, a deep user need assessment is required. After user needs have been identified, the existing system will be developed to match these needs. The theoretical background is achieved through exploring the literature of project manufacturing, development project success factors and different frameworks and tools for development project execution. The focus of this research is rather in customer need assessment than in system’s technical expertise. To ensure the deep understanding of customer needs this study is executed by action research method. As a result of this research the information system for project manufacturing coordination was developed to respond revealed needs of the stakeholders. The new system improves the quality of the manufacturing information, eliminates waste in manufacturing coordination processes and offers a better visibility to the project manufacturing. Hence it provides a solid base for the further development of project manufacturing.

Detecting Attacks in CyberManufacturing Systems: Additive Manufacturing Example

Directory of Open Access Journals (Sweden)

Wu Mingtao

2017-01-01

Full Text Available CyberManufacturing System is a vision for future manufacturing where physical components are fully integrated with computational processes in a connected environment. However, realizing the vision requires that its security be adequately ensured. This paper presents a vision-based system to detect intentional attacks on additive manufacturing processes, utilizing machine learning techniques. Particularly, additive manufacturing systems have unique vulnerabilities to malicious attacks, which can result in defective infills but without affecting the exterior. In order to detect such infill defects, the research uses simulated 3D printing process images as well as actual 3D printing process images to compare accuracies of machine learning algorithms in classifying, clustering and detecting anomalies on different types of infills. Three algorithms - (i random forest, (ii k nearest neighbor, and (iii anomaly detection - have been adopted in the research and shown to be effective in detecting such defects.

Manufacturing footprint optimisation: a necessity for manufacturing network in changing business environment

DEFF Research Database (Denmark)

Yang, Cheng; Farooq, Sami; Johansen, John

2010-01-01

Facing the unpredictable financial crisis, optimising the footprint can be the biggest and most important transformation a manufacturer can undertake. In order to realise the optimisation, fundamental understanding on manufacturing footprint is required. Different elements of manufacturing...... footprint have been investigated independently in the existing literature. In this paper, for the purpose of relationship exploration between different elements, manufacturing footprints of three industrial companies are traced historically. Based on them, four reasons for the transformation...

Manufacturing data analytics using a virtual factory representation.

Science.gov (United States)

Jain, Sanjay; Shao, Guodong; Shin, Seung-Jun

2017-01-01

Large manufacturers have been using simulation to support decision-making for design and production. However, with the advancement of technologies and the emergence of big data, simulation can be utilised to perform and support data analytics for associated performance gains. This requires not only significant model development expertise, but also huge data collection and analysis efforts. This paper presents an approach within the frameworks of Design Science Research Methodology and prototyping to address the challenge of increasing the use of modelling, simulation and data analytics in manufacturing via reduction of the development effort. The use of manufacturing simulation models is presented as data analytics applications themselves and for supporting other data analytics applications by serving as data generators and as a tool for validation. The virtual factory concept is presented as the vehicle for manufacturing modelling and simulation. Virtual factory goes beyond traditional simulation models of factories to include multi-resolution modelling capabilities and thus allowing analysis at varying levels of detail. A path is proposed for implementation of the virtual factory concept that builds on developments in technologies and standards. A virtual machine prototype is provided as a demonstration of the use of a virtual representation for manufacturing data analytics.

Fostering Innovation in the Manufacturing Sector through R&D Consortia

Science.gov (United States)

McKittrick, M.

2017-12-01

In the U.S. Department of Energy, the Advanced Manufacturing Office (AMO) has the mission to catalyze research, development and adoption of energy-related advanced manufacturing technologies and practices to drive U.S. economic competitiveness and energy productivity. Within strategic areas of manufacturing, AMO brings together manufacturers, suppliers, institutes of higher education, national laboratories, and state and local governments in public-private R&D consortia to accelerate technology innovation. One such R&D Consortia is the Critical Materials Institute (CMI), established in 2013 and led by Ames Laboratory. CMI is a sustained, multidisciplinary effort to develop solutions across the materials lifecycle of materials essential to clean energy technologies and manufacturing, as well as reduce the impact of supply chain disruptions associated with these valuable resources. By bringing together scientists and engineers from diverse disciplines, CMI is addressing challenges in critical materials, including mineral processing, manufacture, substitution, efficient use, and end-of-life recycling; integrating scientific research, engineering innovation, manufacturing and process improvements; and developing a holistic solution to the materials challenges facing the nation. It includes expertise from four national laboratories, seven universities, and ten industry partners to minimize materials criticality as an impediment to the commercialization of clean energy technologies.

Toward New-Generation Intelligent Manufacturing

Directory of Open Access Journals (Sweden)

Ji Zhou

2018-02-01

Full Text Available Intelligent manufacturing is a general concept that is under continuous development. It can be categorized into three basic paradigms: digital manufacturing, digital-networked manufacturing, and new-generation intelligent manufacturing. New-generation intelligent manufacturing represents an in-depth integration of new-generation artificial intelligence (AI technology and advanced manufacturing technology. It runs through every link in the full life-cycle of design, production, product, and service. The concept also relates to the optimization and integration of corresponding systems; the continuous improvement of enterprises’ product quality, performance, and service levels; and reduction in resources consumption. New-generation intelligent manufacturing acts as the core driving force of the new industrial revolution and will continue to be the main pathway for the transformation and upgrading of the manufacturing industry in the decades to come. Human-cyber-physical systems (HCPSs reveal the technological mechanisms of new-generation intelligent manufacturing and can effectively guide related theoretical research and engineering practice. Given the sequential development, cross interaction, and iterative upgrading characteristics of the three basic paradigms of intelligent manufacturing, a technology roadmap for “parallel promotion and integrated development” should be developed in order to drive forward the intelligent transformation of the manufacturing industry in China. Keywords: Advanced manufacturing, New-generation intelligent manufacturing, Human-cyber-physical system, New-generation AI, Basic paradigms, Parallel promotion, Integrated development

An Assessment of Advanced Manufacturing Technologies Implementation in Manufacturing Enterprises

Directory of Open Access Journals (Sweden)

Ghulam Yasin Shaikh

2011-04-01

Full Text Available The implementation of AMTs (Advanced Manufacturing Technologies has always been the high interest and core issue for the manufacturing enterprises to get rapid production for global market place. The developed countries have achieved its competitive advantage by implementing this unique model of technologies with full range of systems. In developing countries, the implementation of such technologies is not much common due to so many reasons, (political, social, economical and technical but entrepreneurs of growing economies are contemplating to reshape long term strategy to adopt Computer systems oriented technologies in their manufacturing companies to meet the growing needs of their indigenous market on one hand and to make a place in the international market on the other. Although, very few manufacturing organization do meet the global market requirements. But there is still lot of efforts to be taken for world class competition. An attempt has been made in this paper to develop a conceptual model taking in to account the three parameters such as, Direct, Indirect and Administrative AMTs. This research work further attempts to present an empirical data analysis conducted in the manufacturing enterprises in province of Sindh, Pakistan. The overall indigenous progress of manufacturing enterprises as according to the data collected from 60 companies reveals that the AMTs systems are partially understood and practiced that is also one of the cause towards slow progress of national exchequer.

77 FR 38269 - Approval for Expanded Manufacturing Authority; Foreign-Trade Subzone 7M; Amgen Manufacturing...

Science.gov (United States)

2012-06-27

... Manufacturing Authority; Foreign-Trade Subzone 7M; Amgen Manufacturing Limited (Biotechnology and Healthcare... the scope of manufacturing authority on behalf of Amgen Manufacturing Limited (Amgen), within Subzone..., the Board hereby orders: The application to expand the scope of manufacturing authority under zone...

Additive manufacturing.

Science.gov (United States)

Mumith, A; Thomas, M; Shah, Z; Coathup, M; Blunn, G

2018-04-01

Increasing innovation in rapid prototyping (RP) and additive manufacturing (AM), also known as 3D printing, is bringing about major changes in translational surgical research. This review describes the current position in the use of additive manufacturing in orthopaedic surgery. Cite this article: Bone Joint J 2018;100-B:455-60.

Strengthening the Competitiveness and Sustainability of a Semiconductor Manufacturer with Cloud Manufacturing

Directory of Open Access Journals (Sweden)

Toly Chen

2014-01-01

Full Text Available Cloud manufacturing (CMfg is a new-generation service-oriented networked manufacturing model that provides distributed users centralized managed manufacturing resources, ability, and services. CMfg is applied here to a semiconductor manufacturing factory. Benefits are classified into five aspects: cost savings, efficiency, additional data analysis capabilities, flexibility, and closer partner relationships. A strength, weakness, opportunity, and threat (SWOT analysis is done which guides a semiconductor manufacturer in planning CMfg implementation projects. Simulation of a wafer fabrication factory (wafer fab is used as an example. Several CMfg services are proposed for assisting the fab simulation activities through the collaboration of cloud service providers, software vendors, equipment suppliers, and the wafer fab. The connection with the competitiveness and sustainability of a wafer fab is also stressed.

Manufacturing technologies

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-09-01

The Manufacturing Technologies Center is an integral part of Sandia National Laboratories, a multiprogram engineering and science laboratory, operated for the Department of Energy (DOE) with major facilities at Albuquerque, New Mexico, and Livermore, California. Our Center is at the core of Sandia`s Advanced Manufacturing effort which spans the entire product realization process.

Additive Manufacturing Infrared Inspection

Science.gov (United States)

Gaddy, Darrell; Nettles, Mindy

2015-01-01

The Additive Manufacturing Infrared Inspection Task started the development of a real-time dimensional inspection technique and digital quality record for the additive manufacturing process using infrared camera imaging and processing techniques. This project will benefit additive manufacturing by providing real-time inspection of internal geometry that is not currently possible and reduce the time and cost of additive manufactured parts with automated real-time dimensional inspections which deletes post-production inspections.

Associations between occupational stress, burnout and well-being among manufacturing workers: mediating roles of psychological capital and self-esteem.

Science.gov (United States)

Wang, Ziyue; Liu, Hongbo; Yu, Haijian; Wu, Yanwen; Chang, Shuai; Wang, Lie

2017-11-15

Occupational stress is an important risk factor for mental health among occupational population. Exploring related mediators of workers' mental health are important to improve their health and performance. Our study aims to explore the relationships between work stress, positive psychological resources, burnout and well-being. The study was performed during the period of June and July in 2015. A questionnaire that consisted of the Effort-reward Imbalance Scale, the Maslach Burnout Inventory-General Survey, the Psychological Capital Questionnaire, the Rosenberg Self-esteem Scale, the Flourishing Scale, as well as demographic and working factors. Psychological capital mediated the associations of effort-reward imbalance and emotional exhaustion, cynicism, professional efficacy and well-being. Self-esteem mediated the associations of effort-reward imbalance ratio with cynicism, professional efficacy and well-being, and mediated the associations of overcommitment and cynicism, professional efficacy and well-being. The findings indicated that enhancing positive psychological resources could be considered in developing intervention strategies for psychological health among manufacturing employees.

Open manufacturing system using MMS service and object oriented manufacturing equipment

International Nuclear Information System (INIS)

Kim, Dong Hoon; Song, Jun Yeob; Kim, Sun Ho

2007-01-01

Manufacturing equipment should be integrated to construct CIM (Computer Integrated Manufacturing) environment, but several economical and technological difficulties may be arisen in case heterogeneous systems are integrated into each other. MMS (Manufacturing Message Specification) can be effective in such a case, but the problem is that MMS-related products are comparatively expensive and the existing manufacturing equipment mostly do not support MMS. This study was focused on developing a gateway suitable to a non-MMS-compatible CNC machine-tool, and on implementing OSI (Open System Interconnection) upper layer on TCP/IP. The development system was applied to a cell controller by means of heterogeneous equipment under CIM environment, and to evaluate interoperability and portability

Design for Additive Manufacturing: Trends, opportunities, considerations, and constraints

DEFF Research Database (Denmark)

Thompson, Mary Kathryn; Moroni, Giovanni; Vaneker, Tom

2016-01-01

The past few decades have seen substantial growth in Additive Manufacturing (AM) technologies. However, this growth has mainly been process-driven. The evolution of engineering design to take advantage of the possibilities afforded by AM and to manage the constraints associated with the technology...... has lagged behind. This paper presents the major opportunities, constraints, and economic considerations for Design for Additive Manufacturing. It explores issues related to design and redesign for direct and indirect AM production. It also highlights key industrial applications, outlines future...

Design for Additive Manufacturing: Trends, opportunities, considerations, and constraints

DEFF Research Database (Denmark)

Thompson, Mary Kathryn; Moroni, Giovanni; Vaneker, Tom

2016-01-01

has lagged behind. This paper presents the major opportunities, constraints, and economic considerations for Design for Additive Manufacturing. It explores issues related to design and redesign for direct and indirect AM production. It also highlights key industrial applications, outlines future......The past few decades have seen substantial growth in Additive Manufacturing (AM) technologies. However, this growth has mainly been process-driven. The evolution of engineering design to take advantage of the possibilities afforded by AM and to manage the constraints associated with the technology...

Guidelines on preparation of documentation required in PET radiopharmaceutical manufacturing

International Nuclear Information System (INIS)

2001-01-01

This article made by the Nuclear Pharmacy Working Group, subcommittee on Medical Application of Cyclotron-Produced Radionuclides, Medical Science and Pharmaceutical Committee, Japan Radioisotope Association, described the actual examples of Standards, Standard Operating Procedure, Documents and so on for the purpose of operation along the Standards of Compounds Labeled with Positron Nuclides Approved as Established Techniques for Medical Use (2001 Revision). Examples were the organization for manufacturing and management, standard format of the product (for [ 18 F]2-deoxy-2-fluoro-D-glucose), standard for process control of manufacture, standard for control of manufacturing and hygiene, standard for quality, and standard operating procedures for entering and leaving the manufacturing facility, for the clean-bench and for the test of floating micro-particles. The second item involved the definition of the cyclotron target ( 18 O), generation of 18 F by the reaction (p, n), purification of the product, and prescription: the third item; storage of the product and manufacturing process control: and the fourth; education and training of personnel, and health management. (K.H.)

Industrial & Manufacturing Engineering | Classification | College of

Science.gov (United States)

Electrical Engineering Instructional Laboratories Student Resources Industrial & Manufacturing Engineering Industrial & Manufacturing Engineering Academic Programs Industrial & Manufacturing Engineering Major Industrial & Manufacturing Engineering Minor Industrial & Manufacturing Engineering

The Hybrid Lean System to Improve Manufacturing Environment

Directory of Open Access Journals (Sweden)

Ahmad Ahmad Nur Aizat

2017-01-01

Full Text Available Lean manufacturing is a systematic approch could increase manufacturing competitiveness by identifying and elminating waste through lean tools. However, these tools are often categorized into different groups, continues to be difficult for companies to select the most appropriate lean tool to be adopted, especially in respect of the SMEs whose knowledge of lean tools and associated principles are limited. This study is to propose solution on how to implement appropriate lean tools in food manufacturing industry located at Rengit, Johor. Qualitative method is used as a methodology to see the changes after the implementation of lean tools. Interview session also a part of method to collect data from respondents. The finding from this paper shows that implementation of an appropriate lean tool will help to eliminate waste in industry sector, maintain and control the inventory, improve quality of the product and improve overall operational process.

Advanced manufacturing technologies modern machining, advanced joining, sustainable manufacturing

CERN Document Server

2017-01-01

This book provides details and collective information on working principle, process mechanism, salient features, and unique applications of various advanced manufacturing techniques and processes belong. The book is divided in three sessions covering modern machining methods, advanced repair and joining techniques and, finally, sustainable manufacturing. The latest trends and research aspects of those fields are highlighted.

US manufacturing imports from China and employment in the Mexican manufacturing sector

Directory of Open Access Journals (Sweden)

Jorge Eduardo Mendoza Cota

2016-09-01

Full Text Available Since 2001 the manufacturing sector of Mexico has experienced a reduced growth rate. This study estimates the impact of U.S. and Chinese industrial activity on the demand for labor in the manufacturing sector of Mexico. With data on industrial activity, Chinese exports, wages and the peso-dollar exchange rate, a time series cointegration model is developed. The results show that exports from China to the USA and manufacturing wages have affected labor demand negatively, while factors such as the U.S. industrial production and the exchange rate tend to encourage manufacturing activity.

Green Manufacturing Fundamentals and Applications

CERN Document Server

2013-01-01

Green Manufacturing: Fundamentals and Applications introduces the basic definitions and issues surrounding green manufacturing at the process, machine and system (including supply chain) levels. It also shows, by way of several examples from different industry sectors, the potential for substantial improvement and the paths to achieve the improvement. Additionally, this book discusses regulatory and government motivations for green manufacturing and outlines the path for making manufacturing more green as well as making production more sustainable. This book also: • Discusses new engineering approaches for manufacturing and provides a path from traditional manufacturing to green manufacturing • Addresses regulatory and economic issues surrounding green manufacturing • Details new supply chains that need to be in place before going green • Includes state-of-the-art case studies in the areas of automotive, semiconductor and medical areas as well as in the supply chain and packaging areas Green Manufactu...

A Taxonomy of Manufacturing Strategies

OpenAIRE

Jeffrey G. Miller; Aleda V. Roth

1994-01-01

This paper describes the development and analysis of a numerical taxonomy of manufacturing strategies. The taxonomy was developed with standard methods of cluster analysis, and is based on the relative importance attached to eleven competitive capabilities defining the manufacturing task of 164 large American manufacturing business units. Three distinct clusters of manufacturing strategy groups were observed. Though there is an industry effect, all three manufacturing strategy types are obser...

189 An Analysis of the Operational Environments of Manufacturing ...

African Journals Online (AJOL)

First Lady

2013-01-28

Jan 28, 2013 ... Specifically, the case study was Manufacturers Association of. Nigeria (MAN), Abia ... enterprises in Aba are concentrated in the production of light and consumer oriented goods. ..... beneficiaries in designing. Source: Field ...

Optimized manufacturable porous materials

DEFF Research Database (Denmark)

Andreassen, Erik; Andreasen, Casper Schousboe; Jensen, Jakob Søndergaard

Topology optimization has been used to design two-dimensional material structures with specific elastic properties, but optimized designs of three-dimensional material structures are more scarsely seen. Partly because it requires more computational power, and partly because it is a major challenge...... to include manufacturing constraints in the optimization. This work focuses on incorporating the manufacturability into the optimization procedure, allowing the resulting material structure to be manufactured directly using rapid manufacturing techniques, such as selective laser melting/sintering (SLM....../S). The available manufacturing methods are best suited for porous materials (one constituent and void), but the optimization procedure can easily include more constituents. The elasticity tensor is found from one unit cell using the homogenization method together with a standard finite element (FE) discretization...

Intelligent Manufacturing in the Context of Industry 4.0: A Review

Directory of Open Access Journals (Sweden)

Ray Y. Zhong

2017-10-01

Full Text Available Our next generation of industry—Industry 4.0—holds the promise of increased flexibility in manufacturing, along with mass customization, better quality, and improved productivity. It thus enables companies to cope with the challenges of producing increasingly individualized products with a short lead-time to market and higher quality. Intelligent manufacturing plays an important role in Industry 4.0. Typical resources are converted into intelligent objects so that they are able to sense, act, and behave within a smart environment. In order to fully understand intelligent manufacturing in the context of Industry 4.0, this paper provides a comprehensive review of associated topics such as intelligent manufacturing, Internet of Things (IoT-enabled manufacturing, and cloud manufacturing. Similarities and differences in these topics are highlighted based on our analysis. We also review key technologies such as the IoT, cyber-physical systems (CPSs, cloud computing, big data analytics (BDA, and information and communications technology (ICT that are used to enable intelligent manufacturing. Next, we describe worldwide movements in intelligent manufacturing, including governmental strategic plans from different countries and strategic plans from major international companies in the European Union, United States, Japan, and China. Finally, we present current challenges and future research directions. The concepts discussed in this paper will spark new ideas in the effort to realize the much-anticipated Fourth Industrial Revolution.

Make-to-order manufacturing - new approach to management of manufacturing processes

Science.gov (United States)

Saniuk, A.; Waszkowski, R.

2016-08-01

Strategic management must now be closely linked to the management at the operational level, because only in such a situation the company can be flexible and can quickly respond to emerging opportunities and pursue ever-changing strategic objectives. In these conditions industrial enterprises seek constantly new methods, tools and solutions which help to achieve competitive advantage. They are beginning to pay more attention to cost management, economic effectiveness and performance of business processes. In the article characteristics of make-to-order systems (MTO) and needs associated with managing such systems is identified based on the literature analysis. The main aim of this article is to present the results of research related to the development of a new solution dedicated to small and medium enterprises manufacture products solely on the basis of production orders (make-to- order systems). A set of indicators to enable continuous monitoring and control of key strategic areas this type of company is proposed. A presented solution includes the main assumptions of the following concepts: the Performance Management (PM), the Balanced Scorecard (BSC) and a combination of strategic management with the implementation of operational management. The main benefits of proposed solution are to increase effectiveness of MTO manufacturing company management.

Knowledge Transfer and Manufacturing Relocation in International Manufacturing Networks

DEFF Research Database (Denmark)

Madsen, Erik Skov

2014-01-01

This paper is built on six longitudinal case studies of knowledge transfer in manufacturing relocation. By focusing on tacit and explicit knowledge the paper introduces a model for identification of knowledge in relation to four task situations on the shop floor in a manufacturing environment...... after relocation. Finally the paper discusses how “dispatching capacity” and “absorptive capacity” can improve the process....

Micro/Nano manufacturing

DEFF Research Database (Denmark)

Tosello, Guido

2017-01-01

Micro- and nano-scale manufacturing has been the subject of an increasing amount of interest and research effort worldwide in both academia and industry over the past 10 years.Traditional (MEMS) manufacturing, but also precision manufacturing technologies have been developed to cover micro......-scale dimensions and accuracies. Furthermore, these fundamentally different technology ecosystems are currently combined in order to exploit strengths of both platforms. One example is the use of lithography-based technologies to establish nanostructures that are subsequently transferred to 3D geometries via...

77 FR 16158 - Current Good Manufacturing Practice in Manufacturing, Processing, Packing, or Holding of Drugs...

Science.gov (United States)

2012-03-20

.... FDA-1997-N-0518] (formerly 97N-0300) Current Good Manufacturing Practice in Manufacturing, Processing... labeling control provisions of the current good manufacturing practice (CGMP) regulations for human and... GOOD MANUFACTURING PRACTICE FOR FINISHED PHARMACEUTICALS 0 1. The authority citation for 21 CFR part...

Virtual CIM and Digital Manufacturing

Institute of Scientific and Technical Information of China (English)

Sev V.Nagalingam; Grier C.I.Lin

2006-01-01

Manufacturing enterprises play an important role in improving the economic environment of a country.Today, the capability to produce high quality products with shorter delivery time and the ability to produce according to the diverse customer requirements has become the characteristics of successful manufacturing industries. Application of intelligent manufacturing systems and Computer integrated manufacturing (CIM) are the most effective methods for overcoming the issues faced by present day manufactures while retaining the employment level and revenue of a country in today's highly competitive global market. With the developments taking place in CIM and its related technologies, the application of CIM in manufacturing enterprises has become a reality from the dream. This paper highlights the historical developments towards automation and the need for CIM systems. Furthermore, it analyses some new terms such as agile manufacturing, digital manufacturing, agent-based manufacturing and others, which have been emerging recently, and argues all these new technologies are the subsystems of CIM. In addition, this paper provides a new direction in CIM to fulfil the emerging challenges in today's global market and to satisfy the emerging need of virtual enterprises in the form of Virtual CIM.

Strategic Roles of Manufacturing

DEFF Research Database (Denmark)

Yang, Cheng

with the trend of globalisation, how do industrial companies develop their global manufacturing networks? These two questions are actually interlinked. On the one hand, facing increasing offshoring and outsourcing of production activities, industrial companies have to understand how to develop their global...... manufacturing networks. On the other hand, ongoing globalisation also brings tremendous impacts to post-industrial economies (e.g. Denmark). A dilemma therefore arises, i.e. whether it is still necessary to keep manufacturing in these post-industrial economies; if yes, what kinds of roles manufacturing should...

Commercial-scale biotherapeutics manufacturing facility for plant-made pharmaceuticals.

Science.gov (United States)

Holtz, Barry R; Berquist, Brian R; Bennett, Lindsay D; Kommineni, Vally J M; Munigunti, Ranjith K; White, Earl L; Wilkerson, Don C; Wong, Kah-Yat I; Ly, Lan H; Marcel, Sylvain

2015-10-01

Rapid, large-scale manufacture of medical countermeasures can be uniquely met by the plant-made-pharmaceutical platform technology. As a participant in the Defense Advanced Research Projects Agency (DARPA) Blue Angel project, the Caliber Biotherapeutics facility was designed, constructed, commissioned and released a therapeutic target (H1N1 influenza subunit vaccine) in manufacturing facilities, with the capacity to process over 3500 kg of plant biomass per week in an automated multilevel growing environment using proprietary LED lighting. The facility can commission additional plant grow rooms that are already built to double this capacity. In addition to the commercial-scale manufacturing facility, a pilot production facility was designed based on the large-scale manufacturing specifications as a way to integrate product development and technology transfer. The primary research, development and manufacturing system employs vacuum-infiltrated Nicotiana benthamiana plants grown in a fully contained, hydroponic system for transient expression of recombinant proteins. This expression platform has been linked to a downstream process system, analytical characterization, and assessment of biological activity. This integrated approach has demonstrated rapid, high-quality production of therapeutic monoclonal antibody targets, including a panel of rituximab biosimilar/biobetter molecules and antiviral antibodies against influenza and dengue fever. © 2015 Society for Experimental Biology, Association of Applied Biologists and John Wiley & Sons Ltd.

Robotics and automation in manufacture

International Nuclear Information System (INIS)

Glasgow, J.R.

1989-01-01

NEI involvement in Heysham II and Torness included contracts for equipment both for the Nuclear Island and for non-nuclear associated plant. Fundamental to the approach to manufacture was the capital investment in plant and facilities to ensure the quality requirements were met with economic production methods and prompt delivery. Some of the production facilities for a selection of varied components are described. Examples of subsequent development of facilities are given to illustrate their current capability. (author)

Roughness study on homogeneous layer panels manufactured from treated wood waste

Directory of Open Access Journals (Sweden)

Maria Fátima do Nascimento

2017-02-01

Full Text Available Natural resource exploration is growing, highlighting woods and joinery waste, wood industries and the like. This study presents homogeneous particleboard (PPH roughness characterization manufactured from treated wood waste. Normative document with values of Brazilian Technical Standard Association ABNT NBR 8404 (1984, was adopted as a reference. The results show that the manufactured PPH showed roughness class N 10, with roughness values (Ra of less than 12.5 microns.

Manufacture of disposal canisters

International Nuclear Information System (INIS)

Nolvi, L.

2009-12-01

The report summarizes the development work carried out in the manufacturing of disposal canister components, and present status, in readiness for manufacturing, of the components for use in assembly of spent nuclear fuel disposal canister. The disposal canister consist of two major components: the nodular graphite cast iron insert and overpack of oxygen-free copper. The manufacturing process for copper components begins with a cylindrical cast copper billet. Three different manufacturing processes i.e. pierce and draw, extrusion and forging are being developed, which produce a seamless copper tube or a tube with an integrated bottom. The pierce and draw process, Posiva's reference method, makes an integrated bottom possible and only the lid requires welding. Inserts for BWR-element are cast with 12 square channels and inserts for VVER 440-element with 12 round channels. Inserts for EPR-elements have four square channels. Casting of BWR insert type has been studied so far. Experience of casting inserts for PWR, which is similar to the EPR-type, has been got in co-operation with SKB. The report describes the processes being developed for manufacture of disposal canister components and some results of the manufacturing experiments are presented. Quality assurance and quality control in manufacture of canister component is described. (orig.)

The development of clean-burning, noncatalytic manufactured fireplaces

International Nuclear Information System (INIS)

Broome, F.H.

1992-01-01

Concern for the air quality of this country in general and the Western states in particular has brought sharp focus from regulators on the emissions of Particulate Matter (PM) from all wood-burning appliances. This concern was a driving force which led to the development of a clean-burning fireplace. Many Western areas have begun to limit installation of wood-burning appliances in new construction. Some jurisdictions allow only Environmental Protection Agency (EPA) certified appliances. Currently no federal test methods or standards exist for fireplaces so the Manufactured Fireplace Industry, through the Hearth Products Association (HPA), set about to develop suitable test methods and standards for manufactured fireplaces

Large-scale additive manufacturing with bioinspired cellulosic materials.

Science.gov (United States)

Sanandiya, Naresh D; Vijay, Yadunund; Dimopoulou, Marina; Dritsas, Stylianos; Fernandez, Javier G

2018-06-05

Cellulose is the most abundant and broadly distributed organic compound and industrial by-product on Earth. However, despite decades of extensive research, the bottom-up use of cellulose to fabricate 3D objects is still plagued with problems that restrict its practical applications: derivatives with vast polluting effects, use in combination with plastics, lack of scalability and high production cost. Here we demonstrate the general use of cellulose to manufacture large 3D objects. Our approach diverges from the common association of cellulose with green plants and it is inspired by the wall of the fungus-like oomycetes, which is reproduced introducing small amounts of chitin between cellulose fibers. The resulting fungal-like adhesive material(s) (FLAM) are strong, lightweight and inexpensive, and can be molded or processed using woodworking techniques. We believe this first large-scale additive manufacture with ubiquitous biological polymers will be the catalyst for the transition to environmentally benign and circular manufacturing models.

Organizing for manufacturing innovation. The case of Flexible Manufacturing Systems

DEFF Research Database (Denmark)

Boer, Harry; Krabbendam, Koos

1992-01-01

addressing the manufacturing innovation process are even fewer and provide little insight into its true nature. Consequently, little is known about the effective organization of such processes. In the present article an organization model of manufacturing innovation is described, and its practicability...... the implementation of new technology effectively. This is not surprising, considering the innovative nature of this process. Although there is a host of literature on innovation, organization and (the benefits of) new technology, the literature in which these areas are linked together is scarce. Publications...... assessed using the results of seven case studies of the implementation of flexible manufacturing systems in British, Belgian and Dutch mechanical engineering companies....

Appraising manufacturing location

NARCIS (Netherlands)

Steenhuis, H.J.; de Bruijn, E.J.

2002-01-01

International location of manufacturing activities is an issue for managers of manufacturing companies as well as public policy makers. For managers, the issue is relevant because international locations offer opportunities for lowering costs due to productivity improvements. For governments the

An update on coating/manufacturing techniques of microneedles.

Science.gov (United States)

Tarbox, Tamara N; Watts, Alan B; Cui, Zhengrong; Williams, Robert O

2017-12-29

Recently, results have been published for the first successful phase I human clinical trial investigating the use of dissolving polymeric microneedles… Even so, further clinical development represents an important hurdle that remains in the translation of microneedle technology to approved products. Specifically, the potential for accumulation of polymer within the skin upon repeated application of dissolving and coated microneedles, combined with a lack of safety data in humans, predicates a need for further clinical investigation. Polymers are an important consideration for microneedle technology-from both manufacturing and drug delivery perspectives. The use of polymers enables a tunable delivery strategy, but the scalability of conventional manufacturing techniques could arguably benefit from further optimization. Micromolding has been suggested in the literature as a commercially viable means to mass production of both dissolving and swellable microneedles. However, the reliance on master molds, which are commonly manufactured using resource intensive microelectronics industry-derived processes, imparts notable material and design limitations. Further, the inherently multi-step filling and handling processes associated with micromolding are typically batch processes, which can be challenging to scale up. Similarly, conventional microneedle coating processes often follow step-wise batch processing. Recent developments in microneedle coating and manufacturing techniques are highlighted, including micromilling, atomized spraying, inkjet printing, drawing lithography, droplet-born air blowing, electro-drawing, continuous liquid interface production, 3D printing, and polyelectrolyte multilayer coating. This review provides an analysis of papers reporting on potentially scalable production techniques for the coating and manufacturing of microneedles.

Utility of Big Area Additive Manufacturing (BAAM) For The Rapid Manufacture of Customized Electric Vehicles

Energy Technology Data Exchange (ETDEWEB)

Love, Lonnie J [ORNL

2015-08-01

This Oak Ridge National Laboratory (ORNL) Manufacturing Development Facility (MDF) technical collaboration project was conducted in two phases as a CRADA with Local Motors Inc. Phase 1 was previously reported as Advanced Manufacturing of Complex Cyber Mechanical Devices through Community Engagement and Micro-manufacturing and demonstrated the integration of components onto a prototype body part for a vehicle. Phase 2 was reported as Utility of Big Area Additive Manufacturing (BAAM) for the Rapid Manufacture of Customized Electric Vehicles and demonstrated the high profile live printing of an all-electric vehicle using ONRL s Big Area Additive Manufacturing (BAAM) technology. This demonstration generated considerable national attention and successfully demonstrated the capabilities of the BAAM system as developed by ORNL and Cincinnati, Inc. and the feasibility of additive manufacturing of a full scale electric vehicle as envisioned by the CRADA partner Local Motors, Inc.

ACE - Manufacturer Identification Code (MID)

Data.gov (United States)

Department of Homeland Security — The ACE Manufacturer Identification Code (MID) application is used to track and control identifications codes for manufacturers. A manufacturer is identified on an...

Manufacturing Math Classes: An Instructional Program Guide for Manufacturing Workers.

Science.gov (United States)

McBride, Pamela G.; And Others

This program guide documents a manufacturing job family curriculum that develops competence in generic work force education skills through three courses: Reading Rulers, Charts, and Gauges and Math for Manufacturing Workers I and II. An annotated table of contents lists a brief description of the questions answered in each section. An introduction…

From Traditional Manufacturing towards Virtual Servi-Manufacturing: Gabriel’s Journey

DEFF Research Database (Denmark)

Wæhrens, Brian Vejrum; Slepniov, Dmitrij

2011-01-01

The case examines how Gabriel, a Danish textile company, transformed itself from being a traditional textile manufacturer to becoming an innovative virtual servi-manufacturer. The case covers the main milestones in Gabriel’s recent history, explores the main reasons for the transformation...... attempts to reconcile market requirements with its operations configurations and capabilities....

MEDICAL MANUFACTURING INNOVATIONS

Directory of Open Access Journals (Sweden)

Cosma Sorin Cosmin

2015-02-01

Full Text Available The purpose of these studies was to improve the design and manufacturing process by selective laser melting, of new medical implants. After manufacturing process, the implants were measured, microscopically and mechanical analyzed. Implants manufactured by AM can be an attractive option for surface coatings to improve the osseointegration process. The main advantages of customized implants made by AM process are: the precise adaptation to the region of implantation, better cosmesis, reduced surgical times and better performance over their generic counterparts. These medical manufacturing changes the way that the surgeons are planning surgeries and engineers are designing custom implant. AM process has eliminated the constraints of shape, size, internal structure and mechanical properties making it possible for fabrication of implants that conform to the physical and mechanical requirements of implantation according to CT images. This article will review some custom implants fabricated in DME using biocompatible titanium.

Benchmarks of Global Clean Energy Manufacturing

Energy Technology Data Exchange (ETDEWEB)

Sandor, Debra [National Renewable Energy Lab. (NREL), Golden, CO (United States); Chung, Donald [National Renewable Energy Lab. (NREL), Golden, CO (United States); Keyser, David [National Renewable Energy Lab. (NREL), Golden, CO (United States); Mann, Margaret [National Renewable Energy Lab. (NREL), Golden, CO (United States); Engel-Cox, Jill [National Renewable Energy Lab. (NREL), Golden, CO (United States)

2017-01-01

The Clean Energy Manufacturing Analysis Center (CEMAC), sponsored by the U.S. Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE), provides objective analysis and up-to-date data on global supply chains and manufacturing of clean energy technologies. Benchmarks of Global Clean Energy Manufacturing sheds light on several fundamental questions about the global clean technology manufacturing enterprise: How does clean energy technology manufacturing impact national economies? What are the economic opportunities across the manufacturing supply chain? What are the global dynamics of clean energy technology manufacturing?

In-Space Manufacturing Project (prior to FY15: Additive Manufacturing Technology Development)

Data.gov (United States)

National Aeronautics and Space Administration — The In-Space Manufacturing (ISM) project is responsible for developing the manufacturing capabilities that will provide on-demand, sustainable operations during NASA...

The use of LCA for modelling sustainability and environmental impact of manufacturing processes

Energy Technology Data Exchange (ETDEWEB)

Culaba, A.; Purvis, M. [Portsmouth Univ. (United Kingdom). Dept. of Mechanical and Manufacturing Engineering

1995-12-31

Most industries rely significantly on natural resources for raw materials and energy requirements. As a consequence of manufacturing activities, various pollutants are generated in the process. While effects on the environment can be detrimental, wastes and emissions account for a high percentage loss in the overall material balance. Unless these unnecessary losses are minimized and recovered, the environment would continue to be disadvantaged and long-term supply of raw materials and energy would likewise be affected. The key to the analysis of such problems concerns generalised procedures for the modelling of the sustainable use of resources in manufacturing processes and the development of associated sustainability criteria. This requires identifying the various aspects of manufacturing from the time the raw materials are extracted until they have been processed into products and then used or consumed and finally disposed of. The use of life cycle assessment (LCA) methodology encompasses these analyses and that of the identification of environmental effects associated with every stage of the manufacturing process. The presentation concludes that LCA is a very useful and effective tool in providing planners, legislator and decision-makers with the necessary information on the probable impacts of manufacture on the environment as well as underlying legislation, ecological, health standards and emission limits. (author)

The use of LCA for modelling sustainability and environmental impact of manufacturing processes

Energy Technology Data Exchange (ETDEWEB)

Culaba, A; Purvis, M [Portsmouth Univ. (United Kingdom). Dept. of Mechanical and Manufacturing Engineering

1996-12-31

Most industries rely significantly on natural resources for raw materials and energy requirements. As a consequence of manufacturing activities, various pollutants are generated in the process. While effects on the environment can be detrimental, wastes and emissions account for a high percentage loss in the overall material balance. Unless these unnecessary losses are minimized and recovered, the environment would continue to be disadvantaged and long-term supply of raw materials and energy would likewise be affected. The key to the analysis of such problems concerns generalised procedures for the modelling of the sustainable use of resources in manufacturing processes and the development of associated sustainability criteria. This requires identifying the various aspects of manufacturing from the time the raw materials are extracted until they have been processed into products and then used or consumed and finally disposed of. The use of life cycle assessment (LCA) methodology encompasses these analyses and that of the identification of environmental effects associated with every stage of the manufacturing process. The presentation concludes that LCA is a very useful and effective tool in providing planners, legislator and decision-makers with the necessary information on the probable impacts of manufacture on the environment as well as underlying legislation, ecological, health standards and emission limits. (author)

Sugar cane manufacturing is associated with tuberculosis in an indigenous population in Brazil.

Science.gov (United States)

Sacchi, Flávia Patussi Correia; Croda, Mariana Garcia; Estevan, Anderson Oliveira; Ko, Albert I; Croda, Julio

2013-03-01

Tuberculosis (TB) remains one of the leading causes of morbidity and mortality among indigenous peoples in Brazil, and identifying the risk factors for TB in this population secondary to specific epidemiological conditions is essential for recommending interventions aimed at disease control. This case-control study was conducted with an indigenous population between June 2009 and August 2011 in Dourados, Brazil. Tuberculosis cases reported to the national disease surveillance programme were paired with two control cases matched by age and geographic location. There were 63 cases included in this study, and the annual incidence of TB in the indigenous communities examined was 222 (95% CI, 148-321) per 100 000 inhabitants. The multivariate analysis demonstrated that the variables associated with TB infection included male gender (OR 2.6; 95% CI 1.3-5.3), not owning a home (OR 3.4; 95% CI 1.2-10.1), illiteracy (OR 2.4; 95% CI 1.1-5.0), TB contact (OR 2.4; 95% CI 1.2-4.8) and work performed in a sugar cane factory (OR 6.8; 95% CI 1.2-36.9). There is a potential relationship between exposure to sugar cane manufacturing processes and tuberculosis infection among indigenous populations.

Cloud manufacturing: from concept to practice

Science.gov (United States)

Ren, Lei; Zhang, Lin; Tao, Fei; Zhao, Chun; Chai, Xudong; Zhao, Xinpei

2015-02-01

The concept of cloud manufacturing is emerging as a new promising manufacturing paradigm, as well as a business model, which is reshaping the service-oriented, highly collaborative, knowledge-intensive and eco-efficient manufacturing industry. However, the basic concepts about cloud manufacturing are still in discussion. Both academia and industry will need to have a commonly accepted definition of cloud manufacturing, as well as further guidance and recommendations on how to develop and implement cloud manufacturing. In this paper, we review some of the research work and clarify some fundamental terminologies in this field. Further, we developed a cloud manufacturing systems which may serve as an application example. From a systematic and practical perspective, the key requirements of cloud manufacturing platforms are investigated, and then we propose a cloud manufacturing platform prototype, MfgCloud. Finally, a public cloud manufacturing system for small- and medium-sized enterprises (SME) is presented. This paper presents a new perspective for cloud manufacturing, as well as a cloud-to-ground solution. The integrated solution proposed in this paper, including the terminology, MfgCloud, and applications, can push forward this new paradigm from concept to practice.

IDENTIFICATION OF FACTORS AFFECTING LEAN MANUFACTURING IMPLEMENTATION IN PUMP MANUFACTURING COMPANIES IN INDIA - A CASE STUDY

Directory of Open Access Journals (Sweden)

Pratik Badgujar

2016-09-01

Full Text Available Lean Manufacturing has now become a common word in the industrial corridors. It has now been applied to the industries of several domains. No wonder that the Pump manufacturing has also witnessed profound influence of Lean philosophy. Pump manufacturing in India has a history as old as 80 years with more than 500 pump manufacturing units presently working. The present research is an explorative study and was undertaken to identify various factors affecting lean manufacturing implementation in pump manufacturing industry. Analysis of results revealed that the companies registered increase in productivity and reduction in costs and wastes. Lack of understanding, Supply chain and Company culture are found to be the strongest barriers of lean manufacturing implementation. The multiple regression model revealed that Lack of workers support can be fairly reduced by educating them about Lean Manufacturing and establishing a healthy communication with workers. An analysis across different management levels revealed disparity in perceptions and views of personnel. There is a need for top management to align organization toward common goals so as to achieve better success in implementing lean manufacturing.

Manufacturing consumption of energy 1994

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-12-01

This report provides estimates on energy consumption in the manufacturing sector of the U.S. economy based on data from the Manufacturing Energy Consumption Survey. The sample used in this report represented about 250,000 of the largest manufacturing establishments which account for approximately 98 percent of U.S. economic output from manufacturing, and an expected similar proportion of manufacturing energy use. The amount of energy use was collected for all operations of each establishment surveyed. Highlights of the report include profiles for the four major energy-consuming industries (petroleum refining, chemical, paper, and primary metal industries), and an analysis of the effects of changes in the natural gas and electricity markets on the manufacturing sector. Seven appendices are included to provide detailed background information. 10 figs., 51 tabs.

Business process integration between European manufacturers and transport and logistics service providers

DEFF Research Database (Denmark)

Mortensen, Ole; Lemoine, W

2005-01-01

The goal of the Supply Chain Management process is to create value for customers, stakeholders and all supply chain members, through the integration of disparate processes like manufacturing flow management, customer service and order fulfillment. However, many firms fail in the path of achieving...... a total integration. This study illustrates, from an empirical point of view, the problems associated to SC integration among European firms operating in global/international markets. The focus is on the relationship between two echelons in the supply chain: manufacturers and their transport and logistics...... service providers (TLSPs). The paper examines (1) the characteristics of the collaborative partnerships established between manufacturers and their TLSPs; (2) to what extent manufacturers and their TLSPs have integrated SC business processes; (3) the IT used to support the SC cooperation and integration...

Quantitative risk assessment of listeriosis-associated deaths due to Listeria monocytogenes contamination of deli meats originating from manufacture and retail.

Science.gov (United States)

Pradhan, Abani K; Ivanek, Renata; Gröhn, Yrjö T; Bukowski, Robert; Geornaras, Ifigenia; Sofos, John N; Wiedmann, Martin

2010-04-01

The objective of this study was to estimate the relative risk of listeriosis-associated deaths attributable to Listeria monocytogenes contamination in ham and turkey formulated without and with growth inhibitors (GIs). Two contamination scenarios were investigated: (i) prepackaged deli meats with contamination originating solely from manufacture at a frequency of 0.4% (based on reported data) and (ii) retail-sliced deli meats with contamination originating solely from retail at a frequency of 2.3% (based on reported data). Using a manufacture-to-consumption risk assessment with product-specific growth kinetic parameters (i.e., lag phase and exponential growth rate), reformulation with GIs was estimated to reduce human listeriosis deaths linked to ham and turkey by 2.8- and 9-fold, respectively, when contamination originated at manufacture and by 1.9- and 2.8-fold, respectively, for products contaminated at retail. Contamination originating at retail was estimated to account for 76 and 63% of listeriosis deaths caused by ham and turkey, respectively, when all products were formulated without GIs and for 83 and 84% of listeriosis deaths caused by ham and turkey, respectively, when all products were formulated with GIs. Sensitivity analyses indicated that storage temperature was the most important factor affecting the estimation of per annum relative risk. Scenario analyses suggested that reducing storage temperature in home refrigerators to consistently below 7 degrees C would greatly reduce the risk of human listeriosis deaths, whereas reducing storage time appeared to be less effective. Overall, our data indicate a critical need for further development and implementation of effective control strategies to reduce L. monocytogenes contamination at the retail level.

Advanced optical manufacturing digital integrated system

Science.gov (United States)

Tao, Yizheng; Li, Xinglan; Li, Wei; Tang, Dingyong

2012-10-01

It is necessarily to adapt development of advanced optical manufacturing technology with modern science technology development. To solved these problems which low of ration, ratio of finished product, repetition, consistent in big size and high precision in advanced optical component manufacturing. Applied business driven and method of Rational Unified Process, this paper has researched advanced optical manufacturing process flow, requirement of Advanced Optical Manufacturing integrated System, and put forward architecture and key technology of it. Designed Optical component core and Manufacturing process driven of Advanced Optical Manufacturing Digital Integrated System. the result displayed effective well, realized dynamic planning Manufacturing process, information integration improved ratio of production manufactory.

Food Manufacturers and Processors, US and Territories, 2015, EPA Region 9

Data.gov (United States)

U.S. Environmental Protection Agency — This GIS dataset contains point features that represent food manufacturers and processors associated with fifty-four NAICS codes. Establishment-specific information...

Statistical and Computational Techniques in Manufacturing

CERN Document Server

2012-01-01

In recent years, interest in developing statistical and computational techniques for applied manufacturing engineering has been increased. Today, due to the great complexity of manufacturing engineering and the high number of parameters used, conventional approaches are no longer sufficient. Therefore, in manufacturing, statistical and computational techniques have achieved several applications, namely, modelling and simulation manufacturing processes, optimization manufacturing parameters, monitoring and control, computer-aided process planning, etc. The present book aims to provide recent information on statistical and computational techniques applied in manufacturing engineering. The content is suitable for final undergraduate engineering courses or as a subject on manufacturing at the postgraduate level. This book serves as a useful reference for academics, statistical and computational science researchers, mechanical, manufacturing and industrial engineers, and professionals in industries related to manu...

Manufacture of Nano Structures in Polymer Material

DEFF Research Database (Denmark)

Hansen, Hans Nørgaard; Pedersen, H.C.; Staun, Jacob

2003-01-01

The incorporation of micro and nano technology into the products of the future is an area of increasing interest. The ideas for new products based on this technology often take their starting point in specific scientific fields whereas the subsequent design and product development not necessarily...... is based on a systematic approach including manufacturing processes and production system capabilities. The process chain associated with micro and nano injection moulding usually comprises silicon or photoresist mastering, electroforming and polymer processing. Additionally, if the produced polymer...... components are to be used in a microsystem, subsequent handling and assembly is necessary. The present paper describes the process chain related to the manufacture of optical gratings with nanometer-sized structures. The problems of each process step and the challenges of establishing a coherent production...

Additive Manufacturing for Affordable Rocket Engines

Science.gov (United States)

West, Brian; Robertson, Elizabeth; Osborne, Robin; Calvert, Marty

2016-01-01

Additive manufacturing (also known as 3D printing) technology has the potential to drastically reduce costs and lead times associated with the development of complex liquid rocket engine systems. NASA is using 3D printing to manufacture rocket engine components including augmented spark igniters, injectors, turbopumps, and valves. NASA is advancing the process to certify these components for flight. Success Story: MSFC has been developing rocket 3D-printing technology using the Selective Laser Melting (SLM) process. Over the last several years, NASA has built and tested several injectors and combustion chambers. Recently, MSFC has 3D printed an augmented spark igniter for potential use the RS-25 engines that will be used on the Space Launch System. The new design is expected to reduce the cost of the igniter by a factor of four. MSFC has also 3D printed and tested a liquid hydrogen turbopump for potential use on an Upper Stage Engine. Additive manufacturing of the turbopump resulted in a 45% part count reduction. To understanding how the 3D printed parts perform and to certify them for flight, MSFC built a breadboard liquid rocket engine using additive manufactured components including injectors, turbomachinery, and valves. The liquid rocket engine was tested seven times in 2016 using liquid oxygen and liquid hydrogen. In addition to exposing the hardware to harsh environments, engineers learned to design for the new manufacturing technique, taking advantage of its capabilities and gaining awareness of its limitations. Benefit: The 3D-printing technology promises reduced cost and schedule for rocket engines. Cost is a function of complexity, and the most complicated features provide the largest opportunities for cost reductions. This is especially true where brazes or welds can be eliminated. The drastic reduction in part count achievable with 3D printing creates a waterfall effect that reduces the number of processes and drawings, decreases the amount of touch

Manufacturing knowledge management strategy

OpenAIRE

Shaw , Duncan; Edwards , John

2006-01-01

Abstract The study sought to understand the components of knowledge management strategy from the perspective of staff in UK manufacturing organisations. To analyse this topic we took an empirical approach and collaborated with two manufacturing organisations. Our main finding centres on the key components of a knowledge management strategy, and the relationships between it and manufacturing strategy and corporate strategy. Other findings include: the nature of knowledge in manufact...

Copper Disk Manufactured at the Space Optics Manufacturing and Technology Center

Science.gov (United States)

2001-01-01

This photograph shows Wes Brown, Marshall Space Flight Center's (MSFC's) lead diamond tuner, an expert in the science of using diamond-tipped tools to cut metal, inspecting the mold's physical characteristics to ensure the uniformity of its more than 6,000 grooves. This king-size copper disk, manufactured at the Space Optics Manufacturing and Technology Center (SOMTC) at MSFC, is a special mold for making high resolution monitor screens. This master mold will be used to make several other molds, each capable of forming hundreds of screens that have a type of lens called a fresnel lens. Weighing much less than conventional optics, fresnel lenses have multiple concentric grooves, each formed to a precise angle, that together create the curvature needed to focus and project images. The MSFC leads NASA's space optics manufacturing technology development as a technology leader for diamond turning. The machine used to manufacture this mold is among many one-of-a-kind pieces of equipment of MSFC's SOMTC.

Manufacturing fuel-switching capability, 1988

International Nuclear Information System (INIS)

1991-09-01

Historically, about one-third of all energy consumed in the United States has been used by manufacturers. About one-quarter of manufacturing energy is used as feedstocks and raw material inputs that are converted into nonenergy products; the remainder is used for its energy content. During 1988, the most recent year for which data are available, manufacturers consumed 15.5 quadrillion British thermal units (Btu) of energy to produce heat and power and to generate electricity. The manufacturing sector also has widespread capabilities to switch from one fuel to another for either economic or emergency reasons. There are numerous ways to define fuel switching. For the purposes of the Manufacturing Energy Consumption Survey (MECS), fuel switching is defined as the capability to substitute one energy source for another within 30 days with no significant modifications to the fuel-consuming equipment, while keeping production constant. Fuel-switching capability allows manufacturers substantial flexibility in choosing their mix of energy sources. The consumption of a given energy source can be maximized if all possible switching into that energy source takes place. The estimates in this report are based on data collected on the 1988 Manufacturing Energy Consumption Survey (MECS), Forms 846 (A through C). The EIA conducts this national sample survey of manufacturing energy consumption on a triennial basis. The MECS is the only comprehensive source of national-level data on energy-related information for the manufacturing industries. The MECS was first conducted in 1986 to collect data for 1985. This report presents information on the fuel-switching capabilities of manufacturers in 1988. This report is the second of a series based on the 1988 MECS. 8 figs., 31 tabs

Manufacturing fuel-switching capability, 1988

Energy Technology Data Exchange (ETDEWEB)

1991-09-01

Historically, about one-third of all energy consumed in the United States has been used by manufacturers. About one-quarter of manufacturing energy is used as feedstocks and raw material inputs that are converted into nonenergy products; the remainder is used for its energy content. During 1988, the most recent year for which data are available, manufacturers consumed 15.5 quadrillion British thermal units (Btu) of energy to produce heat and power and to generate electricity. The manufacturing sector also has widespread capabilities to switch from one fuel to another for either economic or emergency reasons. There are numerous ways to define fuel switching. For the purposes of the Manufacturing Energy Consumption Survey (MECS), fuel switching is defined as the capability to substitute one energy source for another within 30 days with no significant modifications to the fuel-consuming equipment, while keeping production constant. Fuel-switching capability allows manufacturers substantial flexibility in choosing their mix of energy sources. The consumption of a given energy source can be maximized if all possible switching into that energy source takes place. The estimates in this report are based on data collected on the 1988 Manufacturing Energy Consumption Survey (MECS), Forms 846 (A through C). The EIA conducts this national sample survey of manufacturing energy consumption on a triennial basis. The MECS is the only comprehensive source of national-level data on energy-related information for the manufacturing industries. The MECS was first conducted in 1986 to collect data for 1985. This report presents information on the fuel-switching capabilities of manufacturers in 1988. This report is the second of a series based on the 1988 MECS. 8 figs., 31 tabs.

Modern manufacturing engineering

CERN Document Server

2015-01-01

This book covers recent research and trends in Manufacturing Engineering. The chapters emphasize different aspects of the transformation from materials to products. It provides the reader with fundamental materials treatments and the integration of processes. Concepts such as green and lean manufacturing are also covered in this book.

Reversing the Trend of Large Scale and Centralization in Manufacturing: The Case of Distributed Manufacturing of Customizable 3-D-Printable Self-Adjustable Glasses

Directory of Open Access Journals (Sweden)

Jephias Gwamuri

2014-04-01

Full Text Available Although the trend in manufacturing has been towards centralization to leverage economies of scale, the recent rapid technical development of open-source 3-D printers enables low-cost distributed bespoke production. This paper explores the potential advantages of a distributed manufacturing model of high-value products by investigating the application of 3-D printing to self-refraction eyeglasses. A series of parametric 3-D printable designs is developed, fabricated and tested to overcome limitations identified with mass-manufactured self-correcting eyeglasses designed for the developing world's poor. By utilizing 3-D printable self-adjustable glasses, communities not only gain access to far more diversity in product design, as the glasses can be customized for the individual, but 3-D printing also offers the potential for significant cost reductions. The results show that distributed manufacturing with open-source 3-D printing can empower developing world communities through the ability to print less expensive and customized self-adjusting eyeglasses. This offers the potential to displace both centrally manufactured conventional and self-adjusting glasses while completely eliminating the costs of the conventional optics correction experience, including those of highly-trained optometrists and ophthalmologists and their associated equipment. Although, this study only analyzed a single product, it is clear that other products would benefit from the same approach in isolated regions of the developing world.

CT-assisted agile manufacturing

Science.gov (United States)

Stanley, James H.; Yancey, Robert N.

1996-11-01

The next century will witness at least two great revolutions in the way goods are produced. First, workers will use the medium of virtual reality in all aspects of marketing, research, development, prototyping, manufacturing, sales and service. Second, market forces will drive manufacturing towards small-lot production and just-in-time delivery. Already, we can discern the merging of these megatrends into what some are calling agile manufacturing. Under this new paradigm, parts and processes will be designed and engineered within the mind of a computer, tooled and manufactured by the offspring of today's rapid prototyping equipment, and evaluated for performance and reliability by advanced nondestructive evaluation (NDE) techniques and sophisticated computational models. Computed tomography (CT) is the premier example of an NDE method suitable for future agile manufacturing activities. It is the only modality that provides convenient access to the full suite of engineering data that users will need to avail themselves of computer- aided design, computer-aided manufacturing, and computer- aided engineering capabilities, as well as newly emerging reverse engineering, rapid prototyping and solid freeform fabrication technologies. As such, CT is assured a central, utilitarian role in future industrial operations. An overview of this exciting future for industrial CT is presented.

Telefacturing Based Distributed Manufacturing Environment for Optimal Manufacturing Service by Enhancing the Interoperability in the Hubs

Directory of Open Access Journals (Sweden)

V. K. Manupati

2017-01-01

Full Text Available Recent happenings are surrounding the manufacturing sector leading to intense progress towards the development of effective distributed collaborative manufacturing environments. This evolving collaborative manufacturing not only focuses on digitalisation of this environment but also necessitates service-dependent manufacturing system that offers an uninterrupted approach to a number of diverse, complicated, dynamic manufacturing operations management systems at a common work place (hub. This research presents a novel telefacturing based distributed manufacturing environment for recommending the manufacturing services based on the user preferences. The first step in this direction is to deploy the most advanced tools and techniques, that is, Ontology-based Protégé 5.0 software for transforming the huge stored knowledge/information into XML schema of Ontology Language (OWL documents and Integration of Process Planning and Scheduling (IPPS for multijobs in a collaborative manufacturing system. Thereafter, we also investigate the possibilities of allocation of skilled workers to the best feasible operations sequence. In this context, a mathematical model is formulated for the considered objectives, that is, minimization of makespan and total training cost of the workers. With an evolutionary algorithm and developed heuristic algorithm, the performance of the proposed manufacturing system has been improved. Finally, to manifest the capability of the proposed approach, an illustrative example from the real-time manufacturing industry is validated for optimal service recommendation.

Manufacturing ontology through templates

Directory of Open Access Journals (Sweden)

Diciuc Vlad

2017-01-01

Full Text Available The manufacturing industry contains a high volume of knowhow and of high value, much of it being held by key persons in the company. The passing of this know-how is the basis of manufacturing ontology. Among other methods like advanced filtering and algorithm based decision making, one way of handling the manufacturing ontology is via templates. The current paper tackles this approach and highlights the advantages concluding with some recommendations.

Improved Methods for Production Manufacturing Processes in Environmentally Benign Manufacturing

Directory of Open Access Journals (Sweden)

Yan-Yan Wang

2011-09-01

Full Text Available How to design a production process with low carbon emissions and low environmental impact as well as high manufacturing performance is a key factor in the success of low-carbon production. It is important to address concerns about climate change for the large carbon emission source manufacturing industries because of their high energy consumption and environmental impact during the manufacturing stage of the production life cycle. In this paper, methodology for determining a production process is developed. This methodology integrates process determination from three different levels: new production processing, selected production processing and batch production processing. This approach is taken within a manufacturing enterprise based on prior research. The methodology is aimed at providing decision support for implementing Environmentally Benign Manufacturing (EBM and low-carbon production to improve the environmental performance of the manufacturing industry. At the first level, a decision-making model for new production processes based on the Genetic Simulated Annealing Algorithm (GSAA is presented. The decision-making model considers not only the traditional factors, such as time, quality and cost, but also energy and resource consumption and environmental impact, which are different from the traditional methods. At the second level, a methodology is developed based on an IPO (Input-Process-Output model that integrates assessments of resource consumption and environmental impact in terms of a materials balance principle for batch production processes. At the third level, based on the above two levels, a method for determining production processes that focus on low-carbon production is developed based on case-based reasoning, expert systems and feature technology for designing the process flow of a new component. Through the above three levels, a method for determining the production process to identify, quantify, assess, and optimize the

Big Data Analytics for Smart Manufacturing: Case Studies in Semiconductor Manufacturing

Directory of Open Access Journals (Sweden)

James Moyne

2017-07-01

Full Text Available Smart manufacturing (SM is a term generally applied to the improvement in manufacturing operations through integration of systems, linking of physical and cyber capabilities, and taking advantage of information including leveraging the big data evolution. SM adoption has been occurring unevenly across industries, thus there is an opportunity to look to other industries to determine solution and roadmap paths for industries such as biochemistry or biology. The big data evolution affords an opportunity for managing significantly larger amounts of information and acting on it with analytics for improved diagnostics and prognostics. The analytics approaches can be defined in terms of dimensions to understand their requirements and capabilities, and to determine technology gaps. The semiconductor manufacturing industry has been taking advantage of the big data and analytics evolution by improving existing capabilities such as fault detection, and supporting new capabilities such as predictive maintenance. For most of these capabilities: (1 data quality is the most important big data factor in delivering high quality solutions; and (2 incorporating subject matter expertise in analytics is often required for realizing effective on-line manufacturing solutions. In the future, an improved big data environment incorporating smart manufacturing concepts such as digital twin will further enable analytics; however, it is anticipated that the need for incorporating subject matter expertise in solution design will remain.

78 FR 67117 - Manufacturing Council

Science.gov (United States)

2013-11-08

... preeminent destination for investment in manufacturing throughout the world'' as provided for in Section 4 of... the viewpoint of those stakeholders on current and emerging issues in the manufacturing sector. In... the U.S. manufacturing industry in terms of industry sectors, geographic locations, demographics, and...

Collaborative Cloud Manufacturing: Design of Business Model Innovations Enabled by Cyberphysical Systems in Distributed Manufacturing Systems

Directory of Open Access Journals (Sweden)

Erwin Rauch

2016-01-01

Full Text Available Collaborative cloud manufacturing, as a concept of distributed manufacturing, allows different opportunities for changing the logic of generating and capturing value. Cyberphysical systems and the technologies behind them are the enablers for new business models which have the potential to be disruptive. This paper introduces the topics of distributed manufacturing as well as cyberphysical systems. Furthermore, the main business model clusters of distributed manufacturing systems are described, including collaborative cloud manufacturing. The paper aims to provide support for developing business model innovations based on collaborative cloud manufacturing. Therefore, three business model architecture types of a differentiated business logic are discussed, taking into consideration the parameters which have an influence and the design of the business model and its architecture. As a result, new business models can be developed systematically and new ideas can be generated to boost the concept of collaborative cloud manufacturing within all sustainable business models.

Decentralized manufacturing of cell and gene therapies: Overcoming challenges and identifying opportunities.

Science.gov (United States)

Harrison, Richard P; Ruck, Steven; Medcalf, Nicholas; Rafiq, Qasim A

2017-10-01

Decentralized or "redistributed" manufacturing has the potential to revolutionize the manufacturing approach for cell and gene therapies (CGTs), moving away from the "Fordist" paradigm, delivering health care locally, customized to the end user and, by its very nature, overcoming many of the challenges associated with manufacturing and distribution of high volume goods. In departing from the traditional centralized model of manufacturing, decentralized manufacturing divides production across sites or geographic regions. This paradigm shift imposes significant structural and organisational changes on a business presenting both hidden challenges that must be addressed and opportunities to be embraced. By profoundly adapting business practices, significant advantages can be realized through a democratized value chain, creation of professional-level jobs without geographic restriction to the central hub and a flexibility in response to external pressures and demands. To realize these potential opportunities, however, advances in manufacturing technology and support systems are required, as well as significant changes in the way CGTs are regulated to facilitate multi-site manufacturing. Decentralized manufacturing is likely to be the manufacturing platform of choice for advanced health care therapies-in particular, those with a high degree of personalization. The future success of these promising products will be enhanced by adopting sound business strategies early in development. To realize the benefits that decentralized manufacturing of CGTs has to offer, it is important to examine both the risks and the substantial opportunities present. In this research, we examine both the challenges and the opportunities this shift in business strategy represents in an effort to maximize the success of adoption. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

Life-Cycle Inventory Analysis of Manufacturing Redwood Decking

Science.gov (United States)

Richard D. Bergman; Han-Sup Han; Elaine Oneil; Ivan L. Eastin

2012-01-01

Green building has become increasingly important. Therefore, consumers and builders often take into account the environmental attributes of a building material. This study determined the environmental attributes associated with manufacturing 38-mm × 138-mm (nominal 2 × 6) redwood decking in northern California using the life-cycle inventory method. Primary data...

49 CFR 567.5 - Requirements for manufacturers of vehicles manufactured in two or more stages.

Science.gov (United States)

2010-10-01

... applicable Federal Motor Vehicle Safety Standards, [and Bumper and Theft Prevention Standards, if applicable... 49 Transportation 6 2010-10-01 2010-10-01 false Requirements for manufacturers of vehicles... CERTIFICATION § 567.5 Requirements for manufacturers of vehicles manufactured in two or more stages. (a...

IMHEX fuel cell repeat component manufacturing continuous improvement accomplishments

Energy Technology Data Exchange (ETDEWEB)

Jakaitis, L.A.; Petraglia, V.J.; Bryson, E.S. [M-C Power Corp., Burr Ridge, IL (United States)] [and others

1996-12-31

M-C Power is taking a power generation technology that has been proven in the laboratory and is making it a commercially competitive product. There are many areas in which this technology required scale up and refinement to reach the market entry goals for the IMHEX{reg_sign} molten carbonate fuel cell power plant. One of the primary areas that needed to be addressed was the manufacturing of the fuel cell stack. Up to this point, the fuel cell stack and associated components were virtually hand made for each system to be tested. M-C Power has now continuously manufactured the repeat components for three 250 kW stacks. M-C Power`s manufacturing strategy integrated both evolutionary and revolutionary improvements into its comprehensive commercialization effort. M-C Power`s objectives were to analyze and continuously improve stack component manufacturing and assembly techniques consistent with established specifications and commercial scale production requirements. Evolutionary improvements are those which naturally occur as the production rates are increased and experience is gained. Examples of evolutionary (learning curve) improvements included reducing scrap rates and decreasing raw material costs by buying in large quantities. Revolutionary improvements result in significant design and process changes to meet cost and performance requirements of the market entry system. Revolutionary changes often involve identifying new methods and developing designs to accommodate the new process. Based upon our accomplishments, M-C Power was able to reduce the cost of continuously manufactured fuel cell repeat components from the first to third 250 kW stack by 63%. This paper documents the continuous improvement accomplishments realized by M-C Power during IMHEX{reg_sign} fuel cell repeat component manufacturing.

Development of iFab (Instant Foundry Adaptive Through Bits) Manufacturing Process and Machine Library

Science.gov (United States)

2012-08-01

input shaft , pump, gearbox, rack & pinion… Wheel assy wheel, tire, drive hub, lug, spindle , bearing… Braking brake disc/drum, caliper, friction...processes and associated machines is provided. Progress with respect to Task 3 (to design and develop the Manufacturing Capability Modeling Environment...of Military Ground Vehicle Design , Materials, and Processes ............... 4 4.2 Task 2 Manufacturing Knowledge Characterization

Manufacturing tolerant topology optimization

DEFF Research Database (Denmark)

Sigmund, Ole

2009-01-01

In this paper we present an extension of the topology optimization method to include uncertainties during the fabrication of macro, micro and nano structures. More specifically, we consider devices that are manufactured using processes which may result in (uniformly) too thin (eroded) or too thick...... (dilated) structures compared to the intended topology. Examples are MEMS devices manufactured using etching processes, nano-devices manufactured using e-beam lithography or laser micro-machining and macro structures manufactured using milling processes. In the suggested robust topology optimization...... approach, under- and over-etching is modelled by image processing-based "erode" and "dilate" operators and the optimization problem is formulated as a worst case design problem. Applications of the method to the design of macro structures for minimum compliance and micro compliant mechanisms show...

Feasibility of using Big Area Additive Manufacturing to Directly Manufacture Boat Molds

Energy Technology Data Exchange (ETDEWEB)

Post, Brian K. [ORNL; Chesser, Phillip C. [ORNL; Lind, Randall F. [ORNL; Sallas, Matthew R. [ORNL; Love, Lonnie J. [ORNL

2018-01-01

The goal of this project was to explore the feasibility of using Big Area Additive Manufacturing (BAAM) to directly manufacture a boat mold without the need for coatings. All prior tooling projects with BAAM required the use to thick coatings to overcome the surface finish limitations of the BAAM process. While the BAAM process significantly lowers the cost of building the mold, the high cost element rapidly became the coatings (cost of the material, labor on coating, and finishing). As an example, the time and cost to manufacture the molds for the Wind Turbine project with TPI Composites Inc. and the molds for the submarine project with Carderock Naval Warfare Systems was a fraction of the time and cost of the coatings. For this project, a catamaran boat hull mold was designed, manufactured, and assembled with an additional 0.15” thickness of material on all mold surfaces. After printing, the mold was immediately machined and assembled. Alliance MG, LLC (AMG), the industry partner of this project, experimented with mold release agents on the carbon-fiber reinforced acrylonitrile butadiene styrene (CF ABS) to verify that the material can be directly used as a mold (rather than needing a coating). In addition, for large molds (such as the wind turbine mold with TPI Composites Inc.), the mold only provided the target surface. A steel subframe had to be manufactured to provide structural integrity. If successful, this will significantly reduce the time and cost necessary for manufacturing large resin infusion molds using the BAAM process.

EXPLORING LINKAGES BETWEEN MANUFACTURING FUNCTIONS, OPERATIONS PRIORITIES AND PLANT PERFORMANCE IN MANUFACTURING SMES IN MUMBAI

Directory of Open Access Journals (Sweden)

B.E. Narkhede

2012-03-01

Full Text Available Nowadays, in order for small and medium scale enterprises to excel in performance, it is necessary to have congruency among the manufacturing functions and the operational priorities. In this paper a model is presented to know the relationship between the manufacturing functions, operation priorities and manufacturing performance. Using data collected from small and medium scale manufacturing enterprises in Mumbai and suburban region, this study examines the seven hypothesis based on the relationship between manufacturing functions, priorities and perfomance. The structural equation model is tested using Amos7 software to test the hypothesis. The results show that there exists a positive relation between manufacturing functions and operation priorities as four out of six the dimensions measured such as Process control and implementation, Management of resources, Management of people, and Partnership with supplier are positively related, while two dimensions Training and developing and Teamwork are not positively related. Findings also support strong impact of operation priorities with growth in productivity as a measure of performance.

Power electronic modules design and manufacture

CERN Document Server

Sheng, William W

2004-01-01

IntroductionSelection ProcedureMaterialsInsulating Substrate and MetallizationBase PlateBonding MaterialPower Interconnection and TerminalEncapsulantPlastic Case and Cover Manufacturing of Power IGBT ModulesManufacturing Process Process Control/Long-Term ReliabilityManufacturing FacilitiesManufacturing Flow Charts DesignThermal ManagementCircuit PartitioningDesign Guidelines and ConsiderationsThermal Results of Different Samples

Free-world microelectronic manufacturing equipment

Science.gov (United States)

Kilby, J. S.; Arnold, W. H.; Booth, W. T.; Cunningham, J. A.; Hutcheson, J. D.; Owen, R. W.; Runyan, W. R.; McKenney, Barbara L.; McGrain, Moira; Taub, Renee G.

1988-12-01

Equipment is examined and evaluated for the manufacture of microelectronic integrated circuit devices and sources for that equipment within the Free World. Equipment suitable for the following are examined: single-crystal silicon slice manufacturing and processing; required lithographic processes; wafer processing; device packaging; and test of digital integrated circuits. Availability of the equipment is also discussed, now and in the near future. Very adequate equipment for most stages of the integrated circuit manufacturing process is available from several sources, in different countries, although the best and most widely used versions of most manufacturing equipment are made in the United States or Japan. There is also an active market in used equipment, suitable for manufacture of capable integrated circuits with performance somewhat short of the present state of the art.

Advanced manufacturing: Technology and international competitiveness

Energy Technology Data Exchange (ETDEWEB)

Tesar, A.

1995-02-01

Dramatic changes in the competitiveness of German and Japanese manufacturing have been most evident since 1988. All three countries are now facing similar challenges, and these challenges are clearly observed in human capital issues. Our comparison of human capital issues in German, Japanese, and US manufacturing leads us to the following key judgments: Manufacturing workforces are undergoing significant changes due to advanced manufacturing technologies. As companies are forced to develop and apply these technologies, the constituency of the manufacturing workforce (especially educational requirements, contingent labor, job content, and continuing knowledge development) is being dramatically and irreversibly altered. The new workforce requirements which result due to advanced manufacturing require a higher level of worker sophistication and responsibility.

Advantages of utilizing DMD based rapid manufacturing systems in mass customization applications

Science.gov (United States)

El-Siblani, A.

2010-02-01

The Use of DMD based Rapid Manufacturing Systems has proven to be very advantageous in the production of highly accurate plastic based components for use in mass customization market such as hearing aids, and dental markets. The voxelization process currently afforded with the DLP technology eliminates any layering effect associated with all existing additive Rapid Manufacturing technologies. The smooth accurate surfaces produced in an additive process utilizing DLP technology, through the voxelization approach, allow for the production of custom finished products. The implementation of DLP technology in rapid prototyping and rapid manufacturing systems allow for the usage of highly viscous photopolymer based liquid and paste composites for rapid manufacturing that could not be used in any other additive process prior to implementation of DLP technology in RP and RM systems. It also allowed for the greater throughput in production without sacrificing quality and accuracy.

Lean manufacturing in Indian context: A survey

Directory of Open Access Journals (Sweden)

Rakesh Kumar

2015-04-01

Full Text Available This paper is an attempt to examine the implementation of Lean Manufacturing system in the Indian industries. Predominant elements of Lean Manufacturing, benefits gained after its implementation and obstacles observed by Indian Industry have been recognized. The results of this survey support the opinion that Lean Manufacturing had potential to improve the organizational performance of Indian industries. Nevertheless, Indian industries are required to be passionate to transform their manufacturing by adopting Lean manufacturing to gain the full benefits. A large numbers of literature papers are available on the better side of Lean manufacturing approach and its benefits gained by manufacturing organizations after implementation. But the adverse impacts of Lean manufacturing are not discussed to a great extent. Some drawbacks of Lean manufacturing are also highlighted in this paper.

Advanced Manufacturing Technologies (AMT): Additive Manufactured Hot Fire Planning and Testing in GRC Cell 32 Project

Science.gov (United States)

Fikes, John C.

2014-01-01

The objective of this project is to hot fire test an additively manufactured thrust chamber assembly TCA (injector and thrust chamber). GRC will install the additively manufactured Inconel 625 injector, two additively manufactured (SLM) water cooled Cu-Cr thrust chamber barrels and one additively manufactured (SLM) water cooled Cu-Cr thrust chamber nozzle on the test stand in Cell 32 and perform hot fire testing of the integrated TCA.

Exploring manufacturing solutions for SMEs

DEFF Research Database (Denmark)

Radziwon, Agnieszka; Blichfeldt, Henrik; Bilberg, Arne

This exploratory study provides an overview over current state of manufacturing solutions in small and medium sized enterprises (SMEs) in region of Southern Denmark. Building on manufacturing paradigms, this paper reveals relevant aspects for the development and implementation of improving SMEs...... of manufacturing solutions, which are required to increase their competitiveness and assure sustainable growth....

Launching the dialogue: Safety and innovation as partners for success in advanced manufacturing.

Science.gov (United States)

Geraci, C L; Tinkle, S S; Brenner, S A; Hodson, L L; Pomeroy-Carter, C A; Neu-Baker, N

2018-06-01

Emerging and novel technologies, materials, and information integrated into increasingly automated and networked manufacturing processes or into traditional manufacturing settings are enhancing the efficiency and productivity of manufacturing. Globally, there is a move toward a new era in manufacturing that is characterized by: (1) the ability to create and deliver more complex designs of products; (2) the creation and use of materials with new properties that meet a design need; (3) the employment of new technologies, such as additive and digital techniques that improve on conventional manufacturing processes; and (4) a compression of the time from initial design concept to the creation of a final product. Globally, this movement has many names, but "advanced manufacturing" has become the shorthand for this complex integration of material and technology elements that enable new ways to manufacture existing products, as well as new products emerging from new technologies and new design methods. As the breadth of activities associated with advanced manufacturing suggests, there is no single advanced manufacturing industry. Instead, aspects of advanced manufacturing can be identified across a diverse set of business sectors that use manufacturing technologies, ranging from the semiconductors and electronics to the automotive and pharmaceutical industries. The breadth and diversity of advanced manufacturing may change the occupational and environmental risk profile, challenge the basic elements of comprehensive health and safety (material, process, worker, environment, product, and general public health and safety), and provide an opportunity for development and dissemination of occupational and environmental health and safety (OEHS) guidance and best practices. It is unknown how much the risk profile of different elements of OEHS will change, thus requiring an evolution of health and safety practices. These changes may be accomplished most effectively through multi

Challenges in teaching modern manufacturing technologies

Science.gov (United States)

Ngaile, Gracious; Wang, Jyhwen; Gau, Jenn-Terng

2015-07-01

Teaching of manufacturing courses for undergraduate engineering students has become a challenge due to industrial globalisation coupled with influx of new innovations, technologies, customer-driven products. This paper discusses development of a modern manufacturing course taught concurrently in three institutions where students collaborate in executing various projects. Lectures are developed to contain materials featuring advanced manufacturing technologies, R&D trends in manufacturing. Pre- and post-surveys were conducted by an external evaluator to assess the impact of the course on increase in student's knowledge of manufacturing; increase students' preparedness and confidence in effective communication and; increase students' interest in pursuing additional academic studies and/or a career path in manufacturing and high technology. The surveyed data indicate that the students perceived significant gains in manufacturing knowledge and preparedness in effective communication. The study also shows that implementation of a collaborative course within multiple institutions requires a robust and collective communication platform.

Implementing Manufacturing as a Service : A Pull-Driven Agent-Based Manufacturing Grid

NARCIS (Netherlands)

Moergestel, Leo van; Puik, Erik; Telgen, Daniël; Meyer, John-Jules Ch.

2015-01-01

User requirements and low-cost small quantity production are new challenges for the modern manufacturing industry. This means that small batch sizes or even the manufacturing of one single product should be affordable. To make such a system cost-effective it should be capable to use the available

A quality risk management model approach for cell therapy manufacturing.

Science.gov (United States)

Lopez, Fabio; Di Bartolo, Chiara; Piazza, Tommaso; Passannanti, Antonino; Gerlach, Jörg C; Gridelli, Bruno; Triolo, Fabio

2010-12-01

International regulatory authorities view risk management as an essential production need for the development of innovative, somatic cell-based therapies in regenerative medicine. The available risk management guidelines, however, provide little guidance on specific risk analysis approaches and procedures applicable in clinical cell therapy manufacturing. This raises a number of problems. Cell manufacturing is a poorly automated process, prone to operator-introduced variations, and affected by heterogeneity of the processed organs/tissues and lot-dependent variability of reagent (e.g., collagenase) efficiency. In this study, the principal challenges faced in a cell-based product manufacturing context (i.e., high dependence on human intervention and absence of reference standards for acceptable risk levels) are identified and addressed, and a risk management model approach applicable to manufacturing of cells for clinical use is described for the first time. The use of the heuristic and pseudo-quantitative failure mode and effect analysis/failure mode and critical effect analysis risk analysis technique associated with direct estimation of severity, occurrence, and detection is, in this specific context, as effective as, but more efficient than, the analytic hierarchy process. Moreover, a severity/occurrence matrix and Pareto analysis can be successfully adopted to identify priority failure modes on which to act to mitigate risks. The application of this approach to clinical cell therapy manufacturing in regenerative medicine is also discussed. © 2010 Society for Risk Analysis.

Joint conference of iMEC 2015 (2nd International Manufacturing Engineering Conference & APCOMS 2015 (3rd Asia-Pacific Conference on Manufacturing Systems)

Science.gov (United States)

2016-02-01

The iMEC 2015 is the second International Manufacturing Engineering Conference organized by the Faculty of Manufacturing, Universiti Malaysia Pahang (UMP), held from 12-14th November 2015 in Kuala Lumpur, Malaysia, with a theme "Materials, Manufacturing and Systems for Tomorrow". For the first time, iMEC is organized together with 3rd Asia- Pacific Conference on Manufacturing System (APCOMS 2015) which owned by Fakulti Teknologi Industri, Institut Teknologi Bandung (ITB), Indonesia. This is an extended collaboration between UMP and ITB to intensify knowledge sharing and experiences between higher learning institutions. This conference (iMEC & APCOMS 2015) is a platform for knowledge exchange and the growth of ideas, particularly in manufacturing engineering. The conference aims to bring researchers, academics, scientists, students, engineers and practitioners from around the world together to present their latest findings, ideas, developments and applications related to manufacturing engineering and other related research areas. With rapid advancements in manufacturing engineering, iMEC is an appropriate medium for the associated community to keep pace with the changes. In 2015, the conference theme is “Materials, Manufacturing and Systems for Tomorrow” which reflects the acceleration of knowledge and technology in global manufacturing. The papers in these proceedings are examples of the work presented at the conference. They represent the tip of the iceberg, as the conference attracted over 200 abstracts from Malaysia, Indonesia, Japan, United Kingdom, Australia, India, Bangladesh, South Africa, Turkey and Morocco and 151 full papers were accepted in these proceedings. The conference was run in four parallel sessions with 160 presenters sharing their latest finding in the areas of manufacturing process, systems, advanced materials and automation. The first keynote presentation was given by Prof. B. S. Murthy (IIT, Madras) on "Nanomaterials with Exceptional

Manufacturing a 9-Meter Thermoplastic Composite Wind Turbine Blade: Preprint

Energy Technology Data Exchange (ETDEWEB)

Murray, Robynne [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Snowberg, David R [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Berry, Derek S [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Beach, Ryan [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Rooney, Samantha A [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Swan, Dana [Arkema Inc.

2017-12-06

Currently, wind turbine blades are manufactured from a combination of glass and/or carbon fiber composite materials with a thermoset resin such as epoxy, which requires energy-intensive and expensive heating processes to cure. Newly developed in-situ polymerizing thermoplastic resin systems for composite wind turbine blades polymerize at room temperature, eliminating the heating process and significantly reducing the blade manufacturing cycle time and embodied energy, which in turn reduces costs. Thermoplastic materials can also be thermally welded, eliminating the need for adhesive bonds between blade components and increasing the overall strength and reliability of the blades. As well, thermoplastic materials enable end-of-life blade recycling by reheating and decomposing the materials, which is a limitation of existing blade technology. This paper presents a manufacturing demonstration for a 9-m-long thermoplastic composite wind turbine blade. This blade was constructed in the Composites Manufacturing Education and Technology facility at the National Wind Technology Center at the National Renewable Energy Laboratory (NREL) using a vacuum-assisted resin transfer molding process. Johns Manville fiberglass and an Arkema thermoplastic resin called Elium were used. Additional materials included Armacell-recycled polyethylene terephthalate foam from Creative Foam and low-cost carbon- fiber pultruded spar caps (manufactured in collaboration with NREL, Oak Ridge National Laboratory, Huntsman, Strongwell, and Chomarat). This paper highlights the development of the thermoplastic resin formulations, including an additive designed to control the peak exothermic temperatures. Infusion and cure times of less than 3 hours are also demonstrated, highlighting the efficiency and energy savings associated with manufacturing thermoplastic composite blades.

INDICATORS FOR SUSTAINABILITY IN INDUSTRIAL SYSTEMS CASE STUDY: PAPER MANUFACTURING

Directory of Open Access Journals (Sweden)

Maria Emiliana Fortună

2011-12-01

Full Text Available The paper describes a framework for promoting sustainability by using indicators for sustainable production. The concept of sustainable production is described as it is viewed by various organisms actions involved in the analysis of the sustainable industrial systems.The measure of sustainability is approached considering indicators of sustainable production, addressing both their dimensions and qualitative and quantitative features.The proposed framework refines the sustainability dimension for a case study which envisages sustainability in paper manufacturing. The analysis takes into account the life cycle analysis for the considered process since the environmental impact is seen as an essential sustainability indicator. Paper recycling and reuse is associated environmental and social costs, as a preferred alternative in waste minimization hierarchy in the manufacturing of non-trees eco-friendly paper.Proactive initiatives to improve the environmental performances of production process are considered as powerful tools for improving the paper manufacturing environmental footprint.

Topology Optimization for Additive Manufacturing

DEFF Research Database (Denmark)

Clausen, Anders

This PhD thesis deals with the combination of topology optimization and additive man-ufacturing (AM, also known as 3D-printing). In addition to my own works, the thesis contains a broader review and assessment of the literature within the field. The thesis first presents a classification...... of the various AM technologies, a review of relevant manufacturing materials, the properties of these materials in the additively manufactured part, as well as manufacturing constraints with a potential for design optimization. Subsequently, specific topology optimization formulations relevant for the most im...... for scalable manufacturing. In relation to interface problems it is shown how a flexible void area may be included into a standard minimum compliance problem by employing an additional design variable field and a sensitivity filter. Furthermore, it is shown how the design of coated structures may be modeled...

Business models for additive manufacturing

DEFF Research Database (Denmark)

Hadar, Ronen; Bilberg, Arne; Bogers, Marcel

2015-01-01

Digital fabrication — including additive manufacturing (AM), rapid prototyping and 3D printing — has the potential to revolutionize the way in which products are produced and delivered to the customer. Therefore, it challenges companies to reinvent their business model — describing the logic...... of creating and capturing value. In this paper, we explore the implications that AM technologies have for manufacturing systems in the new business models that they enable. In particular, we consider how a consumer goods manufacturer can organize the operations of a more open business model when moving from...... a manufacturer-centric to a consumer-centric value logic. A major shift includes a move from centralized to decentralized supply chains, where consumer goods manufacturers can implement a “hybrid” approach with a focus on localization and accessibility or develop a fully personalized model where the consumer...

How Development and Manufacturing Will Need to Be Structured-Heads of Development/Manufacturing May 20-21, 2014 Continuous Manufacturing Symposium.

Science.gov (United States)

Nepveux, Kevin; Sherlock, Jon-Paul; Futran, Mauricio; Thien, Michael; Krumme, Markus

2015-03-01

, because of stability constraints or individualization to patients, do not allow centralized manufacturing approaches at all. Again, the entire enterprise needs to be restructured accordingly. The situation of CM in an outsourced operation business model is discussed. Next steps for the industry are recommended. In summary, opportunistic implementation of isolated steps in existing portfolios can be implemented with minimal organizational changes; the availability of the appropriate skills is the determining factor. The implementation of more substantial sequences requires business processes that consider the portfolio, not just single products. Exploration and implementation of complete process chains with consequences for quality decisions do require appropriate organizational support. © 2015 Wiley Periodicals, Inc. and the American Pharmacists Association. © 2014 Wiley Periodicals, Inc. and the American Pharmacists Association.

Application of Additive Manufacturing in Oral and Maxillofacial Surgery.

Science.gov (United States)

Farré-Guasch, Elisabet; Wolff, Jan; Helder, Marco N; Schulten, Engelbert A J M; Forouzanfar, Tim; Klein-Nulend, Jenneke

2015-12-01

Additive manufacturing is the process of joining materials to create objects from digital 3-dimensional (3D) model data, which is a promising technology in oral and maxillofacial surgery. The management of lost craniofacial tissues owing to congenital abnormalities, trauma, or cancer treatment poses a challenge to oral and maxillofacial surgeons. Many strategies have been proposed for the management of such defects, but autogenous bone grafts remain the gold standard for reconstructive bone surgery. Nevertheless, cell-based treatments using adipose stem cells combined with osteoconductive biomaterials or scaffolds have become a promising alternative to autogenous bone grafts. Such treatment protocols often require customized 3D scaffolds that fulfill functional and esthetic requirements, provide adequate blood supply, and meet the load-bearing requirements of the head. Currently, such customized 3D scaffolds are being manufactured using additive manufacturing technology. In this review, 2 of the current and emerging modalities for reconstruction of oral and maxillofacial bone defects are highlighted and discussed, namely human maxillary sinus floor elevation as a valid model to test bone tissue-engineering approaches enabling the application of 1-step surgical procedures and seeding of Good Manufacturing Practice-level adipose stem cells on computer-aided manufactured scaffolds to reconstruct large bone defects in a 2-step surgical procedure, in which cells are expanded ex vivo and seeded on resorbable scaffolds before implantation. Furthermore, imaging-guided tissue-engineering technologies to predetermine the surgical location and to facilitate the manufacturing of custom-made implants that meet the specific patient's demands are discussed. The potential of tissue-engineered constructs designed for the repair of large oral and maxillofacial bone defects in load-bearing situations in a 1-step surgical procedure combining these 2 innovative approaches is

Subcontracting in electronics : from contract manufacturers to providers of electronic manufacturing services (EMS)

OpenAIRE

Liemt van, Gijsbert

2007-01-01

Discusses how the top contract manufacturers in the electronics industry try to become providers of electronic manufacturing services by deepening and broadening the rage of services that they offer and by diversifying into markets other than computing and telecommunications.

Implementation Issues and Challenges in Applying Lean Manufacturing Tools & Techniques in Different Manufacturing Environments

OpenAIRE

Low, Kwee Ang

2005-01-01

Lean Manufacturing has made a significant impact on both the academic and manufacturing circles in the last decade. Fostered by a rapid spread into many other industrial sectors beyond the automotive industry, there has been significant development and "localisation" of the Lean Manufacturing concept in both developed and developing countries worldwide. Despite its successful application in a wide range of industries, little research has been carried out on its successful application outside ...

Sustainable Manufacturing via Multi-Scale, Physics-Based Process Modeling and Manufacturing-Informed Design

Energy Technology Data Exchange (ETDEWEB)

None

2017-04-01

This factsheet describes a project that developed and demonstrated a new manufacturing-informed design framework that utilizes advanced multi-scale, physics-based process modeling to dramatically improve manufacturing productivity and quality in machining operations while reducing the cost of machined components.

Dropwise additive manufacturing of pharmaceutical products for melt-based dosage forms.

Science.gov (United States)

Içten, Elçin; Giridhar, Arun; Taylor, Lynne S; Nagy, Zoltan K; Reklaitis, Gintaras V

2015-05-01

The US Food and Drug Administration introduced the quality by design approach and process analytical technology guidance to encourage innovation and efficiency in pharmaceutical development, manufacturing, and quality assurance. As part of this renewed emphasis on the improvement of manufacturing, the pharmaceutical industry has begun to develop more efficient production processes with more intensive use of online measurement and sensing, real-time quality control, and process control tools. Here, we present dropwise additive manufacturing of pharmaceutical products (DAMPP) as an alternative to conventional pharmaceutical manufacturing methods. This mini-manufacturing process for the production of pharmaceuticals utilizes drop on demand printing technology for automated and controlled deposition of melt-based formulations onto edible substrates. The advantages of drop-on-demand technology, including reproducible production of small droplets, adjustable drop sizing, high placement accuracy, and flexible use of different formulations, enable production of individualized dosing even for low-dose and high-potency drugs. In this work, DAMPP is used to produce solid oral dosage forms from hot melts of an active pharmaceutical ingredient and a polymer. The dosage forms are analyzed to show the reproducibility of dosing and the dissolution behavior of different formulations. © 2015 Wiley Periodicals, Inc. and the American Pharmacists Association.

Dropwise additive manufacturing of pharmaceutical products for solvent-based dosage forms.

Science.gov (United States)

Hirshfield, Laura; Giridhar, Arun; Taylor, Lynne S; Harris, Michael T; Reklaitis, Gintaras V

2014-02-01

In recent years, the US Food and Drug Administration has encouraged pharmaceutical companies to develop more innovative and efficient manufacturing methods with improved online monitoring and control. Mini-manufacturing of medicine is one such method enabling the creation of individualized product forms for each patient. This work presents dropwise additive manufacturing of pharmaceutical products (DAMPP), an automated, controlled mini-manufacturing method that deposits active pharmaceutical ingredients (APIs) directly onto edible substrates using drop-on-demand (DoD) inkjet printing technology. The use of DoD technology allows for precise control over the material properties, drug solid state form, drop size, and drop dynamics and can be beneficial in the creation of high-potency drug forms, combination drugs with multiple APIs or individualized medicine products tailored to a specific patient. In this work, DAMPP was used to create dosage forms from solvent-based formulations consisting of API, polymer, and solvent carrier. The forms were then analyzed to determine the reproducibility of creating an on-target dosage form, the morphology of the API of the final form and the dissolution behavior of the drug over time. DAMPP is found to be a viable alternative to traditional mass-manufacturing methods for solvent-based oral dosage forms. © 2013 Wiley Periodicals, Inc. and the American Pharmacists Association.

Canadian Manufacturing Malaise: Three Hypotheses

Directory of Open Access Journals (Sweden)

Matt Krzepkowski

2013-03-01

Full Text Available The danger in politicians promoting the idea that “Dutch Disease” is responsible for the decline of the Ontario manufacturing sector is that the suggestion implies that Canada’s manufacturing sector will bounce back if only we could slow down oil sands development, or if the Canadian dollar were to devalue. In reality, evidence suggests that the decline in Ontario manufacturing is the result of long-term structural changes in the economy, independent of the rise of the country’s natural-resource sector and the rising dollar. And the sooner policymakers realize that, and stop blaming the decline in manufacturing on Dutch Disease (which holds that a booming natural-resource sector that drives up our dollar makes our manufacturing exports less competitive the sooner they can get to work on helping manufacturing-dependent regions transition to the evolving economy. A closer analysis of Canada’s manufacturing sector shows that jobs in that sector have been disappearing across the country since the end of the Second World War, with the sector’s share of employment falling dramatically well before rapid development began to take hold in the oil sands, and back when Canada’s dollar was still worth far less than the American dollar. It is a trend that has been occurring among most of our OECD peers, including the United States, which may be due to the widespread reallocation of production to lower cost countries. But it is also true that Canada’s manufacturing productivity performance in particular has been declining for a generation, with especially poor performance in the last decade, when labour productivity in Canada grew at just a quarter of the U.S. rate. Meanwhile, capital investment that may have improved the competitiveness of Canadian manufacturing has been anemic. Yet there is no particular reason to lament the scaling-down of manufacturing jobs in Ontario. The province remains just as economically important, as a share of

Robust Manufacturing Control

CERN Document Server

2013-01-01

This contributed volume collects research papers, presented at the CIRP Sponsored Conference Robust Manufacturing Control: Innovative and Interdisciplinary Approaches for Global Networks (RoMaC 2012, Jacobs University, Bremen, Germany, June 18th-20th 2012). These research papers present the latest developments and new ideas focusing on robust manufacturing control for global networks. Today, Global Production Networks (i.e. the nexus of interconnected material and information flows through which products and services are manufactured, assembled and distributed) are confronted with and expected to adapt to: sudden and unpredictable large-scale changes of important parameters which are occurring more and more frequently, event propagation in networks with high degree of interconnectivity which leads to unforeseen fluctuations, and non-equilibrium states which increasingly characterize daily business. These multi-scale changes deeply influence logistic target achievement and call for robust planning and control ...

Green Manufacturing

Energy Technology Data Exchange (ETDEWEB)

Patten, John

2013-12-31

Green Manufacturing Initiative (GMI): The initiative provides a conduit between the university and industry to facilitate cooperative research programs of mutual interest to support green (sustainable) goals and efforts. In addition to the operational savings that greener practices can bring, emerging market demands and governmental regulations are making the move to sustainable manufacturing a necessity for success. The funding supports collaborative activities among universities such as the University of Michigan, Michigan State University and Purdue University and among 40 companies to enhance economic and workforce development and provide the potential of technology transfer. WMU participants in the GMI activities included 20 faculty, over 25 students and many staff from across the College of Engineering and Applied Sciences; the College of Arts and Sciences' departments of Chemistry, Physics, Biology and Geology; the College of Business; the Environmental Research Institute; and the Environmental Studies Program. Many outside organizations also contribute to the GMI's success, including Southwest Michigan First; The Right Place of Grand Rapids, MI; Michigan Department of Environmental Quality; the Michigan Department of Energy, Labor and Economic Growth; and the Michigan Manufacturers Technical Center.

Wide and High Additive Manufacturing

Energy Technology Data Exchange (ETDEWEB)

Post, Brian K. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Roschli, Alex C. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

2017-03-01

The goal of this project is to develop and demonstrate the enabling technologies for Wide and High Additive Manufacturing (WHAM). WHAM will open up new areas of U.S. manufacturing for very large tooling in support of the transportation and energy industries, significantly reducing cost and lead time. As with Big Area Additive Manufacturing (BAAM), the initial focus is on the deposition of composite materials.

Do best manufacturing practices depend on the plant role in international manufacturing networks?

DEFF Research Database (Denmark)

Demeter, Krisztina; Szász, Levente; Boer, Harry

2014-01-01

. This paper investigates the relationship between plant roles and the “goodness” of manufacturing practices using the International Manufacturing Strategy Survey. According to our results plants with higher competence (leaders and contributors) have more best practices than less competent plants. Servers can...

Method for distributed agent-based non-expert simulation of manufacturing process behavior

Science.gov (United States)

Ivezic, Nenad; Potok, Thomas E.

2004-11-30

A method for distributed agent based non-expert simulation of manufacturing process behavior on a single-processor computer comprises the steps of: object modeling a manufacturing technique having a plurality of processes; associating a distributed agent with each the process; and, programming each the agent to respond to discrete events corresponding to the manufacturing technique, wherein each discrete event triggers a programmed response. The method can further comprise the step of transmitting the discrete events to each agent in a message loop. In addition, the programming step comprises the step of conditioning each agent to respond to a discrete event selected from the group consisting of a clock tick message, a resources received message, and a request for output production message.

Quality prediction modeling for multistage manufacturing based on classification and association rule mining

OpenAIRE

Kao Hung-An; Hsieh Yan-Shou; Chen Cheng-Hui; Lee Jay

2017-01-01

For manufacturing enterprises, product quality is a key factor to assess production capability and increase their core competence. To reduce external failure cost, many research and methodology have been introduced in order to improve process yield rate, such as TQC/TQM, Shewhart CycleDeming's 14 Points, etc. Nowadays, impressive progress has been made in process monitoring and industrial data analysis because of the Industry 4.0 trend. Industries start to utilize quality control (QC) methodo...

Hypothesis analysis methods, hypothesis analysis devices, and articles of manufacture

Science.gov (United States)

Sanfilippo, Antonio P [Richland, WA; Cowell, Andrew J [Kennewick, WA; Gregory, Michelle L [Richland, WA; Baddeley, Robert L [Richland, WA; Paulson, Patrick R [Pasco, WA; Tratz, Stephen C [Richland, WA; Hohimer, Ryan E [West Richland, WA

2012-03-20

Hypothesis analysis methods, hypothesis analysis devices, and articles of manufacture are described according to some aspects. In one aspect, a hypothesis analysis method includes providing a hypothesis, providing an indicator which at least one of supports and refutes the hypothesis, using the indicator, associating evidence with the hypothesis, weighting the association of the evidence with the hypothesis, and using the weighting, providing information regarding the accuracy of the hypothesis.

Users guide for WoodCite, a product cost quotation tool for wood component manufacturers [computer program

Science.gov (United States)

Jeff Palmer; Adrienn Andersch; Jan Wiedenbeck; Urs. Buehlmann

2014-01-01

WoodCite is a Microsoft® Access-based application that allows wood component manufacturers to develop product price quotations for their current and potential customers. The application was developed by the U.S. Forest Service and Virginia Polytechnic Institute and State University, in cooperation with the Wood Components Manufacturers Association.

Energy use efficiency in the Indian manufacturing sector: An interstate analysis

International Nuclear Information System (INIS)

Mukherjee, Kankana

2008-01-01

This paper approaches the measurement of energy efficiency from a production theoretic framework and uses Data Envelopment Analysis to measure energy efficiency in the Indian manufacturing sector. Using data from the Annual Survey of Industries for the years 1998-99 through 2003-04, the study compares the energy efficiency in manufacturing across states, based on several models. The results show considerable variation in energy efficiency across states. Comparing the results across our models, we find that the relative pricing of energy does not provide the appropriate incentives for energy conservation. A second-stage regression analysis reveals that states with a larger share of manufacturing output in energy-intensive industries have lower energy efficiency. Also, higher quality labor force associates with higher energy efficiency. Finally, the power sector reforms have not yet had any significant impact on achieving energy efficiency

Improvements in Operational Readiness by Distributing Manufacturing Capability in the Supply Chain through Additive Manufacturing

Science.gov (United States)

2017-12-01

Second, the report presents the results of laboratory tests designed to evaluate additive manufacturing time of four repair parts. C. RESEARCH...since the production repeatability and reliability of the parts are not well understood (Merritt 2015, 9). The Army’s Additive Manufacturing ...that has a single factory that produces all of their products . This definition is expanded to include a network of manufacturing facilities where each

Manufacturing consumption of energy 1991

Energy Technology Data Exchange (ETDEWEB)

1994-12-01

This report provides estimates on energy consumption in the manufacturing sector of the US economy. These estimates are based on data from the 1991 Manufacturing Energy Consumption Survey (MECS). This survey--administered by the Energy End Use and Integrated Statistics Division, Office of Energy Markets and End Use, Energy Information Administration (EIA)--is the most comprehensive source of national-level data on energy-related information for the manufacturing industries.

75 FR 71417 - Manufacturing Council Membership

Science.gov (United States)

2010-11-23

... DEPARTMENT OF COMMERCE International Trade Administration Manufacturing Council Membership AGENCY... marketing programs in support of manufacturing industries, job creation in the manufacturing sector, or the... their travel, living and other personal expenses. Meetings are held regularly and not less than annually...

Joint conference of iMEC 2015 (2nd International Manufacturing Engineering Conference and APCOMS 2015 (3rd Asia-Pacific Conference on Manufacturing Systems)

International Nuclear Information System (INIS)

2016-01-01

The iMEC 2015 is the second International Manufacturing Engineering Conference organized by the Faculty of Manufacturing, Universiti Malaysia Pahang (UMP), held from 12-14th November 2015 in Kuala Lumpur, Malaysia, with a theme 'Materials, Manufacturing and Systems for Tomorrow'. For the first time, iMEC is organized together with 3rd Asia- Pacific Conference on Manufacturing System (APCOMS 2015) which owned by Fakulti Teknologi Industri, Institut Teknologi Bandung (ITB), Indonesia. This is an extended collaboration between UMP and ITB to intensify knowledge sharing and experiences between higher learning institutions. This conference (iMEC and APCOMS 2015) is a platform for knowledge exchange and the growth of ideas, particularly in manufacturing engineering. The conference aims to bring researchers, academics, scientists, students, engineers and practitioners from around the world together to present their latest findings, ideas, developments and applications related to manufacturing engineering and other related research areas. With rapid advancements in manufacturing engineering, iMEC is an appropriate medium for the associated community to keep pace with the changes. In 2015, the conference theme is “Materials, Manufacturing and Systems for Tomorrow” which reflects the acceleration of knowledge and technology in global manufacturing. The papers in these proceedings are examples of the work presented at the conference. They represent the tip of the iceberg, as the conference attracted over 200 abstracts from Malaysia, Indonesia, Japan, United Kingdom, Australia, India, Bangladesh, South Africa, Turkey and Morocco and 151 full papers were accepted in these proceedings. The conference was run in four parallel sessions with 160 presenters sharing their latest finding in the areas of manufacturing process, systems, advanced materials and automation. The first keynote presentation was given by Prof. B. S. Murthy (IIT, Madras) on &apos

Five-Axis Ultrasonic Additive Manufacturing for Nuclear Component Manufacture

Science.gov (United States)

Hehr, Adam; Wenning, Justin; Terrani, Kurt; Babu, Sudarsanam Suresh; Norfolk, Mark

2017-03-01

Ultrasonic additive manufacturing (UAM) is a three-dimensional metal printing technology which uses high-frequency vibrations to scrub and weld together both similar and dissimilar metal foils. There is no melting in the process and no special atmosphere requirements are needed. Consequently, dissimilar metals can be joined with little to no intermetallic compound formation, and large components can be manufactured. These attributes have the potential to transform manufacturing of nuclear reactor core components such as control elements for the High Flux Isotope Reactor at Oak Ridge National Laboratory. These components are hybrid structures consisting of an outer cladding layer in contact with the coolant with neutron-absorbing materials inside, such as neutron poisons for reactor control purposes. UAM systems are built into a computer numerical control (CNC) framework to utilize intermittent subtractive processes. These subtractive processes are used to introduce internal features as the component is being built and for net shaping. The CNC framework is also used for controlling the motion of the welding operation. It is demonstrated here that curved components with embedded features can be produced using a five-axis code for the welder for the first time.

All-Embracing Manufacturing Roadmap System

CERN Document Server

Halevi, Gideon

2012-01-01

All-embracing manufacturing is a system that aims to dissolve the complexity of the manufacturing process and restore the inherent simplicity. It claims that production is very simple and flexible by nature. However, the complexity is a result of the production system approach which makes it rigid and therefore complex. All-embracing manufacturing introduces flexibility to production planning, it eliminates constraints, bottlenecks, and disruptions automatically while it restores the simplicity. No decision is made ahead of time, but only at the time of execution. It introduces technology as dominant part of manufacturing. It is a computer oriented system that imitates human behavior i.e. practically as any of us behave in daily personal life.

Electron Beam Melting Manufacturing Technology for Individually Manufactured Jaw Prosthesis: A Case Report.

Science.gov (United States)

Suska, Felicia; Kjeller, Göran; Tarnow, Peter; Hryha, Eduard; Nyborg, Lars; Snis, Anders; Palmquist, Anders

2016-08-01

In the field of maxillofacial reconstruction, additive manufacturing technologies, specifically electron beam melting (EBM), offer clinicians the potential for patient-customized design of jaw prostheses, which match both load-bearing and esthetic demands. The technique allows an innovative, functional design, combining integrated porous regions for bone ingrowth and secondary biological fixation with solid load-bearing regions ensuring the biomechanical performance. A patient-specific mandibular prosthesis manufactured using EBM was successfully used to reconstruct a patient's mandibular defect after en bloc resection. Over a 9-month follow-up period, the patient had no complications. A short operating time, good esthetic outcome, and high level of patient satisfaction as measured by quality-of-life questionnaires-the European Organisation for Research and Treatment of Cancer QLQ-C30 (30-item quality-of-life core questionnaire) and H&N35 (head and neck cancer module)-were reported for this case. Individually planned and designed EBM-produced prostheses may be suggested as a possible future alternative to fibular grafts or other reconstructive methods. However, the role of porosity, the role of geometry, and the optimal combination of solid and porous parts, as well as surface properties in relation to soft tissues, should be carefully evaluated in long-term clinical trials. Copyright © 2016 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

Pellet to Part Manufacturing System for CNCs

Energy Technology Data Exchange (ETDEWEB)

Roschli, Alex C. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Love, Lonnie J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Post, Brian K. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Chesser, Phillip C. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Lloyd, Peter D. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Bandari, Yashwanth Kumar [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Jones, Jason [Hybrid Manufacturing Technologies, Swadlincote (United Kingdom); Gaul, Katherine T. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

2018-03-14

Oak Ridge National Laboratory’s Manufacturing Demonstration Facility worked with Hybrid Manufacturing Technologies to develop a compact prototype composite additive manufacturing head that can effectively extrude injection molding pellets. The head interfaces with conventional CNC machine tools enabling rapid conversion of conventional machine tools to additive manufacturing tools. The intent was to enable wider adoption of Big Area Additive Manufacturing (BAAM) technology and combine BAAM technology with conventional machining systems.

Additive manufactured serialization

Science.gov (United States)

Bobbitt, III, John T.

2017-04-18

Methods for forming an identifying mark in a structure are described. The method is used in conjunction with an additive manufacturing method and includes the alteration of a process parameter during the manufacturing process. The method can form in a unique identifying mark within or on the surface of a structure that is virtually impossible to be replicated. Methods can provide a high level of confidence that the identifying mark will remain unaltered on the formed structure.

Energetics Manufacturing Technology Center (EMTC)

Data.gov (United States)

Federal Laboratory Consortium — The Energetics Manufacturing Technology Center (EMTC), established in 1994 by the Office of Naval Research (ONR) Manufacturing Technology (ManTech) Program, is Navy...

PowerLight Corporation Lean Manufacturing, PV Manufacturing R&D Phase I Report: 6 December 2001--31 March 2003

Energy Technology Data Exchange (ETDEWEB)

Hargis, L; Botkin, J.

2005-06-01

PowerLight Corporation (PowerLight) has completed Phase I of its PV Manufacturing R&D subcontract, ''PowerGuard Lean Manufacturing,'' Subcontract No. NDO-1-30628-04. The overall technical goal of this project was to reduce the cost of PowerGuard manufacturing while simultaneously improving product quality. This will enable PowerLight to scale up production capacity as the market for PowerGuard continues to grow. Through the introduction of world-class lean manufacturing techniques, PowerLight was to cut out waste in the manufacturing process of PowerGuard. The manufacturing process was to be overhauled with an objective of removing as much as possible those steps that do not add value to the product. Quality of finished goods was also to be improved through the use of statistical process control and error-proofing in the manufacturing process. Factory operations were also to be addressed to streamline those factory activities that support the manufacturing process. This report de tails the progress made toward the above listed goals during the first phase of this subcontract.

Crowd wisdom drives intelligent manufacturing

Directory of Open Access Journals (Sweden)

Jiaqi Lu

2017-03-01

Full Text Available Purpose – A fundamental problem for intelligent manufacturing is to equip the agents with the ability to automatically make judgments and decisions. This paper aims to introduce the basic principle for intelligent crowds in an attempt to show that crowd wisdom could help in making accurate judgments and proper decisions. This further shows the positive effects that crowd wisdom could bring to the entire manufacturing process. Design/methodology/approach – Efforts to support the critical role of crowd wisdom in intelligent manufacturing involve theoretical explanation, including a discussion of several prevailing concepts, such as consumer-to-business (C2B, crowdfunding and an interpretation of the contemporary Big Data mania. In addition, an empirical study with three business cases was conducted to prove the conclusion that our ideas could well explain the current business phenomena and guide the future of manufacturing. Findings – This paper shows that crowd wisdom could help make accurate judgments and proper decisions. It further shows the positive effects that crowd wisdom could bring to the entire manufacturing process. Originality/value – The paper highlights the importance of crowd wisdom in manufacturing with sufficient theoretical and empirical analysis, potentially providing a guideline for future industry.

Integrated and Intelligent Manufacturing: Perspectives and Enablers

Directory of Open Access Journals (Sweden)

Yubao Chen

2017-10-01

Full Text Available With ever-increasing market competition and advances in technology, more and more countries are prioritizing advanced manufacturing technology as their top priority for economic growth. Germany announced the Industry 4.0 strategy in 2013. The US government launched the Advanced Manufacturing Partnership (AMP in 2011 and the National Network for Manufacturing Innovation (NNMI in 2014. Most recently, the Manufacturing USA initiative was officially rolled out to further “leverage existing resources... to nurture manufacturing innovation and accelerate commercialization” by fostering close collaboration between industry, academia, and government partners. In 2015, the Chinese government officially published a 10-year plan and roadmap toward manufacturing: Made in China 2025. In all these national initiatives, the core technology development and implementation is in the area of advanced manufacturing systems. A new manufacturing paradigm is emerging, which can be characterized by two unique features: integrated manufacturing and intelligent manufacturing. This trend is in line with the progress of industrial revolutions, in which higher efficiency in production systems is being continuously pursued. To this end, 10 major technologies can be identified for the new manufacturing paradigm. This paper describes the rationales and needs for integrated and intelligent manufacturing (i2M systems. Related technologies from different fields are also described. In particular, key technological enablers, such as the Internet of Things and Services (IoTS, cyber-physical systems (CPSs, and cloud computing are discussed. Challenges are addressed with applications that are based on commercially available platforms such as General Electric (GE’s Predix and PTC’s ThingWorx.

Manufacturing of superconductive silver/ceramic composites

DEFF Research Database (Denmark)

Seifi, Behrouz; Bech, Jakob Ilsted; Eriksen, Morten

2000-01-01

Manufacturing of superconducting metal/ceramic composites is a rather new discipline within materials forming processes. High Temperature SuperConductors, HTSC, are manufactured applying the Oxide-Powder-In-Tube process, OPIT. A ceramic powder containing lead, calcium, bismuth, strontium, and cop......Manufacturing of superconducting metal/ceramic composites is a rather new discipline within materials forming processes. High Temperature SuperConductors, HTSC, are manufactured applying the Oxide-Powder-In-Tube process, OPIT. A ceramic powder containing lead, calcium, bismuth, strontium...

Prepreg effects on honeycomb composite manufacturing

Science.gov (United States)

Martin, Cary Joseph

Fiber reinforced composites offer many advantages over traditional materials and are widely utilized in aerospace applications. Advantages include a high stiffness to weight ratio and excellent fatigue resistance. However, the pace of new implementation is slow. The manufacturing processes used to transform composite intermediates into final products are poorly understood and are a source of much variability. This limits new implementation and increases the manufacturing costs of existing designs. One such problem is honeycomb core crush, in which a core-stiffened structure collapses during autoclave manufacture, making the structure unusable and increasing the overall manufacturing cost through increased scrap rates. Consequently, the major goal of this research was to investigate the scaling of core crush from prepreg process-structure-property relations to commercial composite manufacture. The material dependent nature of this defect was of particular interest. A methodology and apparatus were developed to measure the frictional resistance of prepreg materials under typical processing conditions. Through a characterization of commercial and experimental prepregs, it was found that core crush behavior was the result of differences in prepreg frictional resistance. This frictional resistance was related to prepreg morphology and matrix rheology and elasticity. Resin composition and prepreg manufacturing conditions were also found to affect manufacturing behavior. Mechanical and dimensional models were developed and demonstrated utility for predicting this crushing behavior. Collectively, this work explored and identified the process-structure-property relations as they relate to the manufacture of composite materials and suggested several avenues by which manufacturing-robust materials may be developed.

27 CFR 19.471 - Manufacture of articles.

Science.gov (United States)

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Manufacture of articles..., DEPARTMENT OF THE TREASURY LIQUORS DISTILLED SPIRITS PLANTS Denaturing Operations and Manufacture of Articles Articles § 19.471 Manufacture of articles. Proprietors shall manufacture, label, mark, and dispose of...

Additively Manufactured, Net Shape Powder Metallurgy Cans for Valves Used in Energy Production

Energy Technology Data Exchange (ETDEWEB)

Peter, William H. [ORNL; Gandy, David [Electric Power Research Institute (EPRI); Lannom, Robert [Oak Ridge National Laboratory (ORNL)

2018-01-01

This CRADA NFE-14-05241 was conducted as a Technical Collaboration project within the Oak Ridge National Laboratory (ORNL) Manufacturing Demonstration Facility (MDF) sponsored by the US Department of Energy Advanced Manufacturing Office (CPS Agreement Number 24761). Opportunities for MDF technical collaborations are listed in the announcement “Manufacturing Demonstration Facility Technology Collaborations for US Manufacturers in Advanced Manufacturing and Materials Technologies” posted at http://web.ornl.gov/sci/manufacturing/docs/FBO-ORNL-MDF-2013-2.pdf. The goal of technical collaborations is to engage industry partners to participate in short-term, collaborative projects within the Manufacturing Demonstration Facility (MDF) to assess applicability and of new energy efficient manufacturing technologies. Research sponsored by the U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, Advanced Manufacturing Office, under contract DE-AC05-00OR22725 with UT-Battelle, LLC.ORNL would like to acknowledge the leadership of EPRI in pulling together the extensive team and managing the execution of the project. In addition, ORNL would like to acknowledge the other contributions of the team members associated with this project. Quintus provided time, access, expertise, and labor of their hydro forming capabilities to evaluate both conventional and additively manufactured tools through this process. Crane ChemPharma Energy provided guidance and information on valve geometries. Carpenter Powder Products was involved with the team providing information on powder processing as it pertains to the canning and hot isostatic pressing of powder. on providing powder and knowledge as it pertains to powder supply for hot isostatic pressing; they also provided powder for the test trials by the industrial team. Bodycote provided guidance on hot isostatic pressing and can requirements. They were also responsible for the hot isostatic pressing of the test valve

The role of manufacturing in affecting the social dimension of sustainability

DEFF Research Database (Denmark)

Sutherland, John W.; Richter, Justin S.; Hutchins, Margot J.

2016-01-01

performance are framed for different stakeholder groups with associated social needs. Methodology development as well as various challenges for social life cycle assessment (S-LCA) are further examined. Efforts to integrate social and another dimension of sustainability are considered, with attention......Manufacturing affects all three dimensions of sustainability: economy, environment, and society. This paper addresses the last of these dimensions. It explores social impacts identified by national level social indicators, frameworks, and principles. The effects of manufacturing on social...... to globalization challenges, including offshoring and reshoring. The paper concludes with a summary of key takeaways and promising directions for future work....

A system approach for reducing the environmental impact of manufacturing and sustainability improvement of nano-scale manufacturing

Science.gov (United States)

Yuan, Yingchun

This dissertation develops an effective and economical system approach to reduce the environmental impact of manufacturing. The system approach is developed by using a process-based holistic method for upstream analysis and source reduction of the environmental impact of manufacturing. The system approach developed consists of three components of a manufacturing system: technology, energy and material, and is useful for sustainable manufacturing as it establishes a clear link between manufacturing system components and its overall sustainability performance, and provides a framework for environmental impact reductions. In this dissertation, the system approach developed is applied for environmental impact reduction of a semiconductor nano-scale manufacturing system, with three case scenarios analyzed in depth on manufacturing process improvement, clean energy supply, and toxic chemical material selection. The analysis on manufacturing process improvement is conducted on Atomic Layer Deposition of Al2O3 dielectric gate on semiconductor microelectronics devices. Sustainability performance and scale-up impact of the ALD technology in terms of environmental emissions, energy consumption, nano-waste generation and manufacturing productivity are systematically investigated and the ways to improve the sustainability of the ALD technology are successfully developed. The clean energy supply is studied using solar photovoltaic, wind, and fuel cells systems for electricity generation. Environmental savings from each clean energy supply over grid power are quantitatively analyzed, and costs for greenhouse gas reductions on each clean energy supply are comparatively studied. For toxic chemical material selection, an innovative schematic method is developed as a visual decision tool for characterizing and benchmarking the human health impact of toxic chemicals, with a case study conducted on six chemicals commonly used as solvents in semiconductor manufacturing. Reliability of

Coordinating knowledge transfer within manufacturing networks

DEFF Research Database (Denmark)

Yang, Cheng; Johansen, John; Boer, Harry

2008-01-01

Along with increasing globalization, the management of international manufacturing networks is becoming increasingly important for industrial companies. This paper mainly focuses on the coordination of knowledge transfer within manufacturing networks. In this context, we propose the time......-place matrix as a tool for mapping the distribution of knowledge within manufacturing networks. Using this tool, four important questions about the coordination of knowledge transfer within a manufacturing network are identified: know-where, know-what, know-when, know-how to transfer. The relationships among...

Competitive Perception of Small Indian Manufacturers: A study of Punjab Units

Directory of Open Access Journals (Sweden)

Raj Kumar Gautam

2011-09-01

Full Text Available The paper aims at identifying the main competitors and competitive advantages of small scale manufacturers. The manufacturers were selected from four manufacturing industries producing textiles, bicycle and bicycle parts, food products and beverages and leather and leather products in the state of Punjab, India. The data were collected from 200 units out of which 173 units were considered for data analysis purposes. In this study, a number of statements indicating the relevant quality certification, competition and cluster association were developed and the respondents were asked to respond to the statement on a five-point likert scale. The Kruskal-Wallis test was applied to know the significant differences among the respondents with regards to different industries, age, and turnover groups with respect to the impact of cluster association. The test was applied at an assumed p-value =0.05. The statements with less than 0.05 p-value are considered significant and those with p-value more than the assumed p-value are considered to be insignificant. The weighted rankings were also calculated for the purpose of data analysis in respect to competitive advantages by assigning the weights 4, 3, 2 and 1 to ranks 1, 2, 3 and 4 respectively.

75 FR 80040 - Manufacturing Council

Science.gov (United States)

2010-12-21

..., developing and marketing programs in support of manufacturing industries, job creation in the manufacturing... relevant contact information such as mailing address, fax, e-mail, fixed and mobile phone numbers and...

Factors associated with the burnout syndrome among professionals in pharmaceutical manufacturing industry and marketing 1234

Directory of Open Access Journals (Sweden)

Jovanović Vesna R.

2017-01-01

Full Text Available Certain authors describe some professions in the healthcare industry as the more susceptible ones to developing a burnout syndrome, while others suggest psychosocial aspects of the workplace as the primary cause in its creation, but not the aspects of the job itself. The main objective of the research was to investigate which specific factors were associated with the burnout syndrome among professionals working in pharmaceutical manufacturing industry and marketing. The study was conducted in June of 2016 as a cross-sectional study and it included 75 university educated professionals from the area of pharmaceutical industry and marketing employed in several local as well as internationally renowned pharmaceutical companies located in Belgrade. The participants were surveyed anonymously. The instruments used in the study were: a general socio-demographic questionnaire, an assertiveness self-evaluation questionnaire and the Maslach Burnout Inventory. An analysis of the responses in the burnout syndrome self-evaluation questionnaires showed that the highest level of burnout was expressed through reduced personal accomplishment (53%. The average assertiveness scores were the lowest in the individuals who demonstrated the highest level of emotional exhaustion (p=0.003, depersonalization (p=0.004, and the highest inefficiency on professional accomplishment scale (p=0.001. A statistically significant difference was observed in frequency and extent of emotional exhaustion with respect to respondents' gender (x2=10.779; p<0.05, as well as the line of business (x2=6.493; p<0.05. Levels of depersonalization are influenced by: line of work (x2=5.393; p<0.05, age (p=0.004, total years of service (p=0.009 and years of service in the profession (p=0.006. A sense of reduced personal accomplishment is influenced by a respondents' profession (x2=10.922; p<0.05 and line of business (x2=7.283; p<0.05. The results obtained in this study might help in identifying

AN EXPLORATORY STUDY OF MANUFACTURING STRATEGY OF PACKAGING PRODUCT-MANUFACTURING COMPANIES IN INDIA

Directory of Open Access Journals (Sweden)

Pradip P. Patil

2012-09-01

Full Text Available This paper presents finding of a survey on manufacturing strategy implementation (MSI adopted by the Indian packaging product manufacturing companies (IPPMC. Though the companies differ in terms of prod uct types (shape, method, content and material of packaging, conversion system, sales volume and sophistication of machinery used, they share common purpose that are used for packaging the product s . With growth in demand for consumer products, packaging f orms basis of differentiating products from competitors. The survey shows emphasis on implementation of manufacturing strategy, key decision areas, identifies competitive priorities, order winners. To get insight, three companies are selected for detailed case studies.

Green manufacturing processes and systems

Energy Technology Data Exchange (ETDEWEB)

Davim, J. Paulo (ed.) [Aveiro Univ. (Portugal). Dept. of Mechanical Engineering, Campus Universitario de Santiago

2013-02-01

This book provides the recent advances on green manufacturing processes and systems for modern industry. Chapter 1 provides information on sustainable manufacturing through environmentally-friendly machining. Chapter 2 is dedicated to environmentally-friendly machining: vegetable based cutting fluids. Chapter 3 describes environmental-friendly joining of tubes. Chapter 4 contains information on concepts, methods and strategies for zero-waste in manufacturing. Finally, chapter 5 is dedicated to the application of hybrid MCDM approach for selecting the best tyre recycling process.

The state of biopharmaceutical manufacturing.

Science.gov (United States)

Molowa, David T; Mazanet, Rosemary

2003-01-01

The manufacturing of protein-based biopharmaceuticals is done in bacterial or mammalian cell cultures. While bacterial cultures are inexpensive, dependable, and approved by regulatory authorities, many complex proteins cannot be manufactured this way. Complex proteins must be manufactured in mammalian cell cultures to produce active products. Mammalian cell culture capacity is limited and has slowed the delivery of necessary biopharmaceutical products to patients. The nature of the production capacity problem and future outlook are critically examined.

Flexibility in fuel manufacturing

International Nuclear Information System (INIS)

Reparaz, A.; Stavig, W.E.; McLees, R.B.

1987-01-01

From its inception Exxon Nuclear has produced both BWR and PWR fuels. This is reflected in a product line that, to date, includes over 20 fuel designs. These range from 6x6 design at one end of the spectrum to the recently introduced 17x17 design. The benefits offered include close tailoring of the fuel design to match the customer's requirements, and the ability to rapidly introduce product changes, such as the axial blanket design, with a minimal impact on manufacturing. This flexibility places a number of demands on the manufacturing organization. Close interfaces must be established, and maintained, between the marketing, product design, manufacturing, purchasing and quality organizations, and the information flows must be immediate and accurate. Production schedules must be well planned and must be maintained or revised to reflect changing circumstances. Finally, the manufacturing facilities must be designed to allow rapid switchover between product designs with minor tooling changes and/or rerouting of product flows to alternate work stations. Among the tools used to manage the flow of information and to maintain the tight integration necessary between the various manufacturing, engineering and quality organizations is a commercially available, computerized planning and tracking system, AMAPS. A real-time production data collection system has been designed which gathers data from each production work station for use by the shop floor control module of AMAPS. Accuracy of input to the system is improved through extensive use of bar codes to gather information on the product as it moves through and between work stations. This computerized preparation of material tracing has an impact on direct manufacturing records, quality control records, nuclear material records and accounting and inventory records. This is of benefit to both Exxon Nuclear and its customers

Post Processing Methods used to Improve Surface Finish of Products which are Manufactured by Additive Manufacturing Technologies: A Review

Science.gov (United States)

Kumbhar, N. N.; Mulay, A. V.

2016-08-01

The Additive Manufacturing (AM) processes open the possibility to go directly from Computer-Aided Design (CAD) to a physical prototype. These prototypes are used as test models before it is finalized as well as sometimes as a final product. Additive Manufacturing has many advantages over the traditional process used to develop a product such as allowing early customer involvement in product development, complex shape generation and also save time as well as money. Additive manufacturing also possess some special challenges that are usually worth overcoming such as Poor Surface quality, Physical Properties and use of specific raw material for manufacturing. To improve the surface quality several attempts had been made by controlling various process parameters of Additive manufacturing and also applying different post processing techniques on components manufactured by Additive manufacturing. The main objective of this work is to document an extensive literature review in the general area of post processing techniques which are used in Additive manufacturing.

NASA Game Changing Development Program Manufacturing Innovation Project

Science.gov (United States)

Tolbert, Carol; Vickers, John

2011-01-01

This presentation examines the new NASA Manufacturing Innovation Project. The project is a part of the Game Changing Development Program which is one element of the Space Technology Programs Managed by Office of the Chief Technologist. The project includes innovative technologies in model-based manufacturing, digital additive manufacturing, and other next generation manufacturing tools. The project is also coupled with the larger federal initiatives in this area including the National Digital Engineering and Manufacturing Initiative and the Advanced Manufacturing Partnership. In addition to NASA, other interagency partners include the Department of Defense, Department of Commerce, NIST, Department of Energy, and the National Science Foundation. The development of game-changing manufacturing technologies are critical for NASA s mission of exploration, strengthening America s manufacturing competitiveness, and are highly related to current challenges in defense manufacturing activities. There is strong consensus across industry, academia, and government that the future competitiveness of U.S. industry will be determined, in large part, by a technologically advanced manufacturing sector. This presentation highlights the prospectus of next generation manufacturing technologies to the challenges faced NASA and by the Department of Defense. The project focuses on maturing innovative/high payoff model-based manufacturing technologies that may lead to entirely new approaches for a broad array of future NASA missions and solutions to significant national needs. Digital manufacturing and computer-integrated manufacturing "virtually" guarantee advantages in quality, speed, and cost and offer many long-term benefits across the entire product lifecycle. This paper addresses key enablers and emerging strategies in areas such as: Current government initiatives, Model-based manufacturing, and Additive manufacturing.

19 CFR 11.2 - Manufactured tobacco.

Science.gov (United States)

2010-04-01

... 19 Customs Duties 1 2010-04-01 2010-04-01 false Manufactured tobacco. 11.2 Section 11.2 Customs... PACKING AND STAMPING; MARKING Packing and Stamping § 11.2 Manufactured tobacco. (a) If the invoice and entry presented for manufactured tobacco specify all the information necessary for prompt determination...

Simulation Environment Synchronizing Real Equipment for Manufacturing Cell

Science.gov (United States)

Inukai, Toshihiro; Hibino, Hironori; Fukuda, Yoshiro

Recently, manufacturing industries face various problems such as shorter product life cycle, more diversified customer needs. In this situation, it is very important to reduce lead-time of manufacturing system constructions. At the manufacturing system implementation stage, it is important to make and evaluate facility control programs for a manufacturing cell, such as ladder programs for programmable logical controllers (PLCs) rapidly. However, before the manufacturing systems are implemented, methods to evaluate the facility control programs for the equipment while mixing and synchronizing real equipment and virtual factory models on the computers have not been developed. This difficulty is caused by the complexity of the manufacturing system composed of a great variety of equipment, and stopped precise and rapid support of a manufacturing engineering process. In this paper, a manufacturing engineering environment (MEE) to support manufacturing engineering processes using simulation technologies is proposed. MEE consists of a manufacturing cell simulation environment (MCSE) and a distributed simulation environment (DSE). MCSE, which consists of a manufacturing cell simulator and a soft-wiring system, is emphatically proposed in detail. MCSE realizes making and evaluating facility control programs by using virtual factory models on computers before manufacturing systems are implemented.

Cladding tube manufacturing technology

International Nuclear Information System (INIS)

Hahn, R.; Jeong, Y. H.; Baek, B. J.; Kim, K. H.; Kim, S. J.; Choi, B. K.; Kim, J. M.

1999-04-01

This report gives an overview of the manufacturing routine of PWR cladding tubes. The routine essentially consists of a series of deformation and annealing processes which are necessary to transform the ingot geometry to tube dimensions. By changing shape, microstructure and structure-related properties are altered simultaneously. First, a short overview of the basics of that part of deformation geometry is given which is related to tube reducing operations. Then those processes of the manufacturing routine which change the microstructure are depicted, and the influence of certain process parameters on microstructure and material properties are shown. The influence of the resulting microstructure on material properties is not discussed in detail, since it is described in my previous report A lloy Development for High Burnup Cladding . Because of their paramount importance still up to now, and because manufacturing data and their influence on properties for other alloys are not so well established or published, the descriptions are mostly related to Zry4 tube manufacturing, and are only in short for other alloys. (author). 9 refs., 46 figs

Cladding tube manufacturing technology

Energy Technology Data Exchange (ETDEWEB)

Hahn, R. [Kraftwerk Union AG, Mulheim (Germany); Jeong, Y.H.; Baek, B.J.; Kim, K.H.; Kim, S.J.; Choi, B.K.; Kim, J.M. [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

1999-04-01

This report gives an overview of the manufacturing routine of PWR cladding tubes. The routine essentially consists of a series of deformation and annealing processes which are necessary to transform the ingot geometry to tube dimensions. By changing shape, microstructure and structure-related properties are altered simultaneously. First, a short overview of the basics of that part of deformation geometry is given which is related to tube reducing operations. Then those processes of the manufacturing routine which change the microstructure are depicted, and the influence of certain process parameters on microstructure and material properties are shown. The influence of the resulting microstructure on material properties is not discussed in detail, since it is described in my previous report 'Alloy Development for High Burnup Cladding.' Because of their paramount importance still up to now, and because manufacturing data and their influence on properties for other alloys are not so well established or published, the descriptions are mostly related to Zry4 tube manufacturing, and are only in short for other alloys. (author). 9 refs., 46 figs.

Additive manufacturing in maxillofacial reconstruction

Directory of Open Access Journals (Sweden)

Dincă Luciana Laura

2017-01-01

Full Text Available In this paper the benefits of using additive manufacturing technologies in maxillofacial reconstruction are highlighted. Based on a real clinical case, the paper describes the manufacture of an implant prototype replacing the right zygomatic bone and a part of maxilla using additive manufacturing technologies. The face is the most expressive part of the human body that makes us unique. It was shown that the maxillofacial prostheses help to improve the psychological state of patients affected by, because low self esteem feeling appears commonly to this patients with the facial defects. The aim of this paper is to show how using additive manufacturing technologies methods within this research, the producing a surgical model will help surgeon to improve the pre-operative planning. For this we used additive manufacturing technologies such as Stereolitography to achieve the biomodel and FDM-fused deposition modelling to obtain a prototype model because these technologies make it possible to obtain prosthesis according to the physical and mechanical requirements of the region of implantation.

Technological dispute for manufacturing population

Directory of Open Access Journals (Sweden)

B.M. Hevko

2017-12-01

Full Text Available New designs of technological equipment are presented – a variegated unit for adjusting the machine for precise manufacturing of a cut or on a tool of a tester, or on a workpiece, and also a design of a control device for measuring average diameters of taps. An important element in the manufacture of cutting tools is the manufacture of appropriate technological equipment. So for the manufacture of taps, it is necessary to develop the design of technological equipment for the adjustment of the necessary design parameters, as well as the design of control devices for their parameters. To provide these operations to instruments are the requirements of accuracy, productivity, stability, cost of production and a number of others. The new design of the technological equipment for the adjustment of the machine for precise manufacturing of the cutting is presented. The design of the control device for measuring the average diameter of the taps is also given. The advantages of the device include improving the quality of processing and working out the design on the technological.

Mechanical properties of open-cell metallic biomaterials manufactured using additive manufacturing

International Nuclear Information System (INIS)

Campoli, G.; Borleffs, M.S.; Amin Yavari, S.; Wauthle, R.; Weinans, H.; Zadpoor, A.A.

2013-01-01

Highlights: ► Finite element (FE) models were used to predict the mechanical properties of porous biomaterials. ► Porous materials were produced using additive manufacturing techniques. ► Manufacturing irregularities need to be implemented in FE models. ► FE models are more accurate than analytical models in predicting mechanical properties. - Abstract: An important practical problem in application of open-cell porous biomaterials is the prediction of the mechanical properties of the material given its micro-architecture and the properties of its matrix material. Although analytical methods can be used for this purpose, these models are often based on several simplifying assumptions with respect to the complex architecture and cannot provide accurate prediction results. The aim of the current study is to present finite element (FE) models that can predict the mechanical properties of porous titanium produced using selective laser melting or selective electron beam melting. The irregularities caused by the manufacturing process including structural variations of the architecture are implemented in the FE models using statistical models. The predictions of FE models are compared with those of analytical models and are tested against experimental data. It is shown that, as opposed to analytical models, the predictions of FE models are in agreement with experimental observations. It is concluded that manufacturing irregularities significantly affect the mechanical properties of porous biomaterials

27 CFR 53.181 - Further manufacture included.

Science.gov (United States)

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Further manufacture... Further manufacture included. (a) In general. The payment of tax imposed by chapter 32 of the Code on the... of any use in further manufacture, or sale as part of a second manufactured article, described in...

Life cycle assessment of regional brick manufacture

Directory of Open Access Journals (Sweden)

López-Aguilar, H. A.

2016-06-01

Full Text Available This document presents a Life Cycle Assessment (LCA study to quantify the environmental cradle-to-gate impact of the manufacture of brick for the construction industry, produced with material of igneous source. Its mineral composition and thermal isolation properties were characterized for use in real estate construction. The LCA results for brick manufacture using this material identified the greatest environmental impact to be associated with material extraction and its proportional cement content. Additionally, this document presents an evaluation of the environmental impact of the manufacturing process by comparing traditional fired clay brick and brick of the material under study. In conclusion, the studied material shows thermal insulation qualities and suitability for the manufacture of bricks with low incorporated energy.Este trabajo presenta un estudio de Análisis de Ciclo de Vida (ACV para cuantificar los impactos ambientales de la cuna a la puerta de la manufactura de ladrillos para la industria de la construcción, fabricados de un material de origen ígneo. Se caracterizó su composición mineralógica y propiedades de aislamiento térmico para ser usado en la construcción de inmuebles. Los resultados ACV de la fabricación de ladrillos de este material, identificaron la mayor contribución a los impactos ambientales asociados a la extracción del material y la cantidad proporcional de cemento. Adicionalmente, se presenta una evaluación comparativa del impacto ambiental entre la manufactura de un ladrillo tradicional de arcilla cocido y de un ladrillo del material en estudio. En conclusión el material estudiado muestra cualidades de aislamiento térmico y es adecuado para la fabricación de ladrillos con baja energía incorporada.

Rapid response manufacturing (RRM). Final CRADA report

Energy Technology Data Exchange (ETDEWEB)

Cain, W.D. [Lockheed Martin Energy Systems, Inc., Oak Ridge, TN (United States); Waddell, W.L. [National Centers for Manufacturing Sciences, Ann Arbor, MI (United States)

1998-02-10

US industry is fighting to maintain its competitive edge in the global market place. Markets fluctuate rapidly. Companies have to be able to respond quickly with improved, high quality, cost efficient products. Because companies and their suppliers are geographically distributed, rapid product realization is dependent on the development of a secure integrated concurrent engineering environment operating across multiple business entities. The way products are developed and brought to market can be improved and made more efficient through the proper incorporation of emerging technologies implemented in a secure environment. This documents the work done under this CRADA to develop capabilities, which permit the effective application, incorporation, and use of advanced technologies in a secure environment to facilitate the product realization process. Lockheed Martin Energy Systems (LMES), through a CRADA with the National Center for Manufacturing Sciences (NCMS), worked within a consortium of major industrial firms--Ford, General Motors, Texas Instruments, United Technologies, and Eastman Kodak--and several small suppliers of advanced manufacturing technology--MacNeal-Schwendler Corp., Teknowledge Corp., Cimplex Corp., Concentra, Spatial Technology, and Structural Dynamics Research Corp. (SDRC)--to create infrastructure to support the development and implementation of secure engineering environments for Rapid Response Manufacturing. The major accomplishment achieved under this CRADA was the demonstration of a prototypical implementation of a broad-based generic framework for automating and integrating the design-to-manufacturing activities associated with machined parts in a secure NWC compliant environment. Specifically, methods needed to permit the effective application, incorporation, and use of advanced technologies in a secure environment to facilitate the product realization process were developed and demonstrated. An important aspect of this demonstration was

Transistor and integrated circuit manufacture

Energy Technology Data Exchange (ETDEWEB)

Colman, D

1978-09-27

This invention relates to the manufacture of transistors and integrated circuits by ion bombardment techniques and is particularly, but not exclusively, of value in the manufacture of so-called integrated injection logic circuitry.

Snap-lock bags with red band: A study of manufacturing characteristics, thermal and chemical properties.

Science.gov (United States)

Sim, Yvonne Hui Ying; Koh, Alaric C W; Lim, Shing Min; Yew, Sok Yee

2015-10-01

Drug packaging is commonly submitted to the Forensic Chemistry and Physics Laboratory of the Health Sciences Authority, Singapore, for examination. The drugs seized are often packaged in plastic bags. These bags are examined for linkages to provide law enforcement with useful associations between the traffickers and drug abusers. The plastic bags submitted may include snap-lock bags, some with a red band located above the snap-lock closure and some without. Current techniques for examination involve looking at the physical characteristics (dimensions, thickness and polarising patterns) and manufacturing marks of these bags. In cases where manufacturing marks on the main body of the bags are poor or absent, the manufacturing characteristics present on the red band can be examined. A study involving approximately 1000 bags was conducted to better understand the variations in the manufacturing characteristics of the red band. This understanding is crucial in helping to determine associations/eliminations between bags. Two instrumental techniques, namely differential scanning calorimetry (DSC) and Fourier transform infrared spectroscopy (FT-IR) were explored to evaluate the effectiveness of examining the chemical composition to discriminate the bags. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Additive manufacturing technologies 3D printing, rapid prototyping, and direct digital manufacturing

CERN Document Server

Gibson, Ian; Stucker, Brent

2015-01-01

This book covers in detail the various aspects of joining materials to form parts. A conceptual overview of rapid prototyping and layered manufacturing is given,  beginning with the fundamentals so that readers can get up to speed quickly. Unusual and emerging applications such as micro-scale manufacturing, medical applications, aerospace, and rapid manufacturing are also discussed. This book provides a comprehensive overview of rapid prototyping technologies as well as support technologies such as software systems, vacuum casting, investment casting, plating, infiltration and other systems. This book also: Reflects recent developments and trends and adheres to the ASTM, SI, and other standards Includes chapters on automotive technology, aerospace technology and low-cost AM technologies Provides a broad range of technical questions to ensure comprehensive understanding of the concepts covered  

A practical discussion of risk management for manufacturing of pharmaceutical products.

Science.gov (United States)

Mollah, A Hamid; Baseman, Harold S; Long, Mike; Rathore, Anurag S

2014-01-01

Quality risk management (QRM) is now a regulatory expectation, and it makes good business sense. The goal of the risk assessment is to increase process understanding and deliver safe and effective product to the patients. Risk analysis and management is an acceptable and effective way to minimize patient risk and determine the appropriate level of controls in manufacturing. While understanding the elements of QRM is important, knowing how to apply them in the manufacturing environment is essential for effective process performance and control. This article will preview application of QRM in pharmaceutical and biopharmaceutical manufacturing to illustrate how QRM can help the reader achieve that objective. There are several areas of risk that a drug company may encounter in pharmaceutical manufacturing, specifically addressing oral solid and liquid formulations. QRM tools can be used effectively to identify the risks and develop strategy to minimize or control them. Risks are associated throughout the biopharmaceutical manufacturing process-from raw material supply through manufacturing and filling operations to final distribution via a controlled cold chain process. Assessing relevant attributes and risks for biotechnology-derived products is more complicated and challenging for complex pharmaceuticals. This paper discusses key risk factors in biopharmaceutical manufacturing. Successful development and commercialization of pharmaceutical products is all about managing risks. If a company was to take zero risk, most likely the path to commercialization would not be commercially viable. On the other hand, if the risk taken was too much, the product is likely to have a suboptimal safety and efficacy profile and thus is unlikely to be a successful product. This article addresses the topic of quality risk management with the key objective of minimizing patient risk while creating an optimal process and product. Various tools are presented to aid implementation of these

Chalon/Saint-Marcel manufacturing plant

International Nuclear Information System (INIS)

2008-01-01

AREVA is the world leader in the design and construction of nuclear power plants, the manufacture of heavy components, and the supply of nuclear fuel and nuclear services such as maintenance and inspection. The Equipment Division provides the widest range of nuclear components and equipment, manufactured at its two facilities in Jeumont, northern France, and St. Marcel, in Burgundy. The St. Marcel plant, set on 35 ha (87.5 acres) near Chalon-sur-Saone, was established in 1973 in a region with a long history of specialized metalworking and mechanical activities to meet the demand for non-military nuclear requirements in France. The site offers two advantages: - excellent facilities for loading and transporting heavy components on the Saone river, - it's proximity to other group sites. Since its completion in 1975, the Chalon/St. Marcel facility has manufactured all the heavy components for French pressurized water reactors (PWRs) ranging from 900 MW to 1500 MW. It has also completed a significant number of export contracts that have made AREVA world leader. Nearly 600 heavy components (reactor vessels, steam generators, pressurizers and closure heads) have been manufactured or are currently being manufactured since the plant opened in 1975. The plant is at the heart of the manufacturing chain for nuclear steam supply systems (NSSS) supplied by AREVA. On the basis of engineering data, the plant manufactures reactor vessels, reactor vessel internals, steam generators, pressurizers and related components such as accumulators, auxiliary heat exchangers and supporting elements. Vessel upper internals Other similar components such as reactor vessels for boiling water reactors (BWR) or high temperature reactors (HTR) and other types of steam generators can also be manufactured in the plant (for example Once Through Steam Generators - OTSG). The basic activities performed at Chalon/St. Marcel are metalworking and heavy machining. These activities are carried out in strict

Semiconductors integrated circuit design for manufacturability

CERN Document Server

Balasinki, Artur

2011-01-01

Because of the continuous evolution of integrated circuit manufacturing (ICM) and design for manufacturability (DfM), most books on the subject are obsolete before they even go to press. That's why the field requires a reference that takes the focus off of numbers and concentrates more on larger economic concepts than on technical details. Semiconductors: Integrated Circuit Design for Manufacturability covers the gradual evolution of integrated circuit design (ICD) as a basis to propose strategies for improving return-on-investment (ROI) for ICD in manufacturing. Where most books put the spotl

Transistor and integrated circuit manufacture

International Nuclear Information System (INIS)

Colman, D.

1978-01-01

This invention relates to the manufacture of transistors and integrated circuits by ion bombardment techniques and is particularly, but not exclusively, of value in the manufacture of so-called integrated injection logic circuitry. (author)

The manufacturing role in fuel performance

International Nuclear Information System (INIS)

Barr, A.P.

1997-01-01

Manufacturing companies have been involved in the CANDU fuel industry for more than 40 years. Early manufacturing contributions were the development of materials and processes used to fabricate the CANDU fuel bundle. As CANDU reactors were commissioned, the manufacturing contribution has been to produce economical, high quality fuel for the CANDU market. (author)

Development work for the manufacture of a blanket shield prototype for ITER

International Nuclear Information System (INIS)

Boireau, B.; Boudot, C.; Cottin, A.; Lorenzetto, P.; Jacquinot, F.; Bucci, P.; Gillia, O.; Vidotto, F.

2006-01-01

In the frame of the blanket development for ITER, an R-and-D programme was implemented for the manufacture of a shield prototype by powder Hot Isostatic Pressing (HIPping). The shield consists of a Stainless steel forged block drilled and machined, at the back of which 3D bent tubes are HIPped inside a powder layer. This paper describes the development work through the manufacturing of several mock ups that leads us to be confident for the shield prototype manufacturing. The paper is divided into 2 parts, the first one related to the machining development and validation, the second one relating to the HIP development and validation. A partial full scale mock up for the machining development (machined PFSMU) was manufactured with no particular problems, all the main identified difficulties in machining like deep drilling and castellation machining where overcome and the mock up was conform to the specification. The manufacturing of a HIPped PFSMU for the HIP development was done after the manufacturing of smaller mock-ups each representing a particular detailed design point. A computer simulation work gave us some design recommendation, and the compared analysis of the numerical simulation and experimental results lead us to predict the distortions on the PFSMU HIPped mock up. The HIPped distortions that were the main uncertainty were assessed through small mock ups and bigger one. The mechanical characteristics of the joints are conform to the specification. Associated to the mock up manufacturing is the ultrasonic test development which consists in designing and manufacturing a miniaturized probe travelling inside the bent tube after the HIP cycle to examine the joint tube / powder among others. This ultrasonic development allowed the examination of the HIPped PFSMU mock up that concluded this development work. (author)

Agile manufacturing from a statistical perspective

Energy Technology Data Exchange (ETDEWEB)

Easterling, R.G. [Sandia National Labs., Albuquerque, NM (United States). New Initiatives Dept.

1995-10-01

The objective of agile manufacturing is to provide the ability to quickly realize high-quality, highly-customized, in-demand products at a cost commensurate with mass production. More broadly, agility in manufacturing, or any other endeavor, is defined as change-proficiency; the ability to thrive in an environment of unpredictable change. This report discusses the general direction of the agile manufacturing initiative, including research programs at the National Institute of Standards and Technology (NIST), the Department of Energy, and other government agencies, but focuses on agile manufacturing from a statistical perspective. The role of statistics can be important because agile manufacturing requires the collection and communication of process characterization and capability information, much of which will be data-based. The statistical community should initiate collaborative work in this important area.

Literature Review on Dynamic Cellular Manufacturing System

Science.gov (United States)

Nouri Houshyar, A.; Leman, Z.; Pakzad Moghadam, H.; Ariffin, M. K. A. M.; Ismail, N.; Iranmanesh, H.

2014-06-01

In previous decades, manufacturers faced a lot of challenges because of globalization and high competition in markets. These problems arise from shortening product life cycle, rapid variation in demand of products, and also rapid changes in manufcaturing technologies. Nowadays most manufacturing companies expend considerable attention for improving flexibility and responsiveness in order to overcome these kinds of problems and also meet customer's needs. By considering the trend toward the shorter product life cycle, the manufacturing environment is towards manufacturing a wide variety of parts in small batches [1]. One of the major techniques which are applied for improving manufacturing competitiveness is Cellular Manufacturing System (CMS). CMS is type of manufacturing system which tries to combine flexibility of job shop and also productivity of flow shop. In addition, Dynamic cellular manufacturing system which considers different time periods for the manufacturing system becomes an important topic and attracts a lot of attention to itself. Therefore, this paper made attempt to have a brief review on this issue and focused on all published paper on this subject. Although, this topic gains a lot of attention to itself during these years, none of previous researchers focused on reviewing the literature of that which can be helpful and useful for other researchers who intend to do the research on this topic. Therefore, this paper is the first study which has focused and reviewed the literature of dynamic cellular manufacturing system.

Manufacturing prototypes for LIPAC beam dump

Energy Technology Data Exchange (ETDEWEB)

Arranz, F., E-mail: fernando.arranz@ciemat.es [CIEMAT, Madrid (Spain); Brañas, B.; Iglesias, D. [CIEMAT, Madrid (Spain); Nomen, O. [IREC, Barcelona (Spain); Rapisarda, D.; Lapeña, J.; Muñoz, A. [CIEMAT, Madrid (Spain); Szcepaniak, B. [GALVANO-T, Windeck (Germany); Manini, J. [CARMAN, Madrid (Spain); Gómez, J. [TRINOS VACUUM, Valencia (Spain)

2014-10-15

Highlights: •Electroforming of copper and electronbeam welding techniques are compared. •Mechanical properties of Cu–stainless steel joint by electroforming are presented. •Achieved manufacturing tolerances are shown. •The difficulties and solutions for the complicated manufacturing are explained. -- Abstract: The purpose of the research is to define the most adequate manufacturing process for the dump of a linear deuteron accelerator. The deuteron beam can be pulsed as well as continuous with energies up to 9 MeV. The maximum beam power is 1.12 MW corresponding to a beam current of 125 mA. The requirements on the surface on which the deuterons will be stopped are quite demanding and the length and slenderness of the cone poses a considerable difficulty in the manufacturing process. The design of the beam dump is based on a copper cone 2500 mm long, 300 mm aperture and 5 to 6.5 mm thickness. Basically only two technologies were found feasible for the manufacturing of the cone: Electroforming and Electron Beam Welding (EBW). The article shows the main results found when manufacturing different prototypes.

Composite fuselage crown panel manufacturing technology

Science.gov (United States)

Willden, Kurtis; Metschan, S.; Grant, C.; Brown, T.

1992-01-01

Commercial fuselage structures contain significant challenges in attempting to save manufacturing costs with advanced composite technology. Assembly issues, material costs, and fabrication of elements with complex geometry are each expected to drive the cost of composite fuselage structures. Boeing's efforts under the NASA ACT program have pursued key technologies for low-cost, large crown panel fabrication. An intricate bond panel design and manufacturing concepts were selected based on the efforts of the Design Build Team (DBT). The manufacturing processes selected for the intricate bond design include multiple large panel fabrication with the Advanced Tow Placement (ATP) process, innovative cure tooling concepts, resin transfer molding of long fuselage frames, and utilization of low-cost material forms. The process optimization for final design/manufacturing configuration included factory simulations and hardware demonstrations. These efforts and other optimization tasks were instrumental in reducing cost by 18 percent and weight by 45 percent relative to an aluminum baseline. The qualitative and quantitative results of the manufacturing demonstrations were used to assess manufacturing risks and technology readiness.

Environmentally benign silicon solar cell manufacturing

Energy Technology Data Exchange (ETDEWEB)

Tsuo, Y.S. [National Renewable Energy Lab., Golden, CO (United States); Gee, J.M. [Sandia National Labs., Albuquerque, NM (United States); Menna, P. [National Agency for New Technologies Energy and Environment, Portici (Italy); Strebkov, D.S.; Pinov, A.; Zadde, V. [Intersolarcenter, Moscow (Russian Federation)

1998-09-01

The manufacturing of silicon devices--from polysilicon production, crystal growth, ingot slicing, wafer cleaning, device processing, to encapsulation--requires many steps that are energy intensive and use large amounts of water and toxic chemicals. In the past two years, the silicon integrated-circuit (IC) industry has initiated several programs to promote environmentally benign manufacturing, i.e., manufacturing practices that recover, recycle, and reuse materials resources with a minimal consumption of energy. Crystalline-silicon solar photovoltaic (PV) modules, which accounted for 87% of the worldwide module shipments in 1997, are large-area devices with many manufacturing steps similar to those used in the IC industry. Obviously, there are significant opportunities for the PV industry to implement more environmentally benign manufacturing approaches. Such approaches often have the potential for significant cost reduction by reducing energy use and/or the purchase volume of new chemicals and by cutting the amount of used chemicals that must be discarded. This paper will review recent accomplishments of the IC industry initiatives and discuss new processes for environmentally benign silicon solar-cell manufacturing.

Micro manufacturing techniques and applications

CERN Document Server

Du, Ruxu; Li, Zifu

2013-01-01

Micro/meso-scale manufacturing has been developed in research fields of machining, forming, materials and others, but its potential to industries are yet to be fully realized. The theme of the current volume was to build a bridge joining academic research and industrial needs in micro manufacturing. Among the 12 papers selected for publication are three keynote addresses onmicro and desktop factories for micro/meso-scale manufacturing applicationsand future visions, tissue cutting mechanics and applications for needlecore biopsy and guidance, and micro-texturing onto amorphous carbonmaterials

Vision-related problems among the workers engaged in jewellery manufacturing.

Science.gov (United States)

Salve, Urmi Ravindra

2015-01-01

American Optometric Association defines Computer Vision Syndrome (CVS) as "complex of eye and vision problems related to near work which are experienced during or related to computer use." This happens when visual demand of the tasks exceeds the visual ability of the users. Even though problems were initially attributed to computer-related activities subsequently similar problems are also reported while carrying any near point task. Jewellery manufacturing activities involves precision designs, setting the tiny metals and stones which requires high visual attention and mental concentration and are often near point task. It is therefore expected that the workers engaged in jewellery manufacturing may also experience symptoms like CVS. Keeping the above in mind, this study was taken up (1) To identify the prevalence of symptoms like CVS among the workers of the jewellery manufacturing and compare the same with the workers working at computer workstation and (2) To ascertain whether such symptoms have any permanent vision-related problems. Case control study. The study was carried out in Zaveri Bazaar region and at an IT-enabled organization in Mumbai. The study involved the identification of symptoms of CVS using a questionnaire of Eye Strain Journal, opthalmological check-ups and measurement of Spontaneous Eye Blink rate. The data obtained from the jewellery manufacturing was compared with the data of the subjects engaged in computer work and with the data available in the literature. A comparative inferential statistics was used. Results showed that visual demands of the task carried out in jewellery manufacturing were much higher than that of carried out in computer-related work.

Diccionario Lean Manufacturing

OpenAIRE

Muñoz Ellner, Sarah María

2016-01-01

El Diccionario Bilingüe de Lean Manufacturing pretende ser un instrumento de apoyo a todo aquel que tenga la responsabilidad de planear, ejecutar o simplemente algún interés con las actividades de Lean Manufacturing, aportando así también conceptos claros tanto en castellano como en inglés, con el fin de entender de forma integral el alcance mismo que puede llegar a tener dicha filosofía, al igual que se proporcionara una serie de siglas y herramientas para la implementación del Lean Manufact...

77 FR 2275 - Manufacturing Council

Science.gov (United States)

2012-01-17

... DEPARTMENT OF COMMERCE International Trade Administration Manufacturing Council AGENCY... candidate's proven experience in promoting, developing and marketing programs in support of manufacturing... participating in Council meetings and events are responsible for their travel, living and other personal...

Laser additive manufacturing of high-performance materials

CERN Document Server

Gu, Dongdong

2015-01-01

This book entitled “Laser Additive Manufacturing of High-Performance Materials” covers the specific aspects of laser additive manufacturing of high-performance new materials components based on an unconventional materials incremental manufacturing philosophy, in terms of materials design and preparation, process control and optimization, and theories of physical and chemical metallurgy. This book describes the capabilities and characteristics of the development of new metallic materials components by laser additive manufacturing process, including nanostructured materials, in situ composite materials, particle reinforced metal matrix composites, etc. The topics presented in this book, similar as laser additive manufacturing technology itself, show a significant interdisciplinary feature, integrating laser technology, materials science, metallurgical engineering, and mechanical engineering. This is a book for researchers, students, practicing engineers, and manufacturing industry professionals interested i...

Registered manufacturers of renewable energy devices

International Nuclear Information System (INIS)

Anon.

1992-01-01

Registered manufacturers of renewable energy devices in India are listed. The list is arranged under the headings : solar water heating system, solar cooker, solar still and water pumping wind mill. In all 38 manufacturers are listed. The list gives the postal address, name of the contact person and phone number of each manufacturer. (M.G.B.)

New workplace practices and firm performance in manufacturing:

DEFF Research Database (Denmark)

Pozzoli, Dario; Cristini, Annalisa

Using data from the 2004 Workplace Employee Relations Survey on British establishments and two surveys on manufacturing firms located in the North of Italy, we look at the diffusion of new workplace practices in the two countries and at their impact on the firm's performance. We find that the Ita......Using data from the 2004 Workplace Employee Relations Survey on British establishments and two surveys on manufacturing firms located in the North of Italy, we look at the diffusion of new workplace practices in the two countries and at their impact on the firm's performance. We find...... that the Italian and British samples differ more in terms of composition of the set practices than in terms of overall incidence, but the statistical associations between some of the practices and the firm's performance are robust across countries. The counterfactual analysis shows that could the Italian firms...

76 FR 33244 - Manufacturing Council

Science.gov (United States)

2011-06-08

... DEPARTMENT OF COMMERCE International Trade Administration Manufacturing Council AGENCY... experience in promoting, developing and marketing programs in support of manufacturing industries, in job... Council meetings and events are responsible for their travel, living and other personal expenses. Meetings...

Building Fitnes for Transfer - Transfering Manufacturing Knowledge Across Borders

DEFF Research Database (Denmark)

Wæhrens, Brian Vejrum; Madsen, Erik Skov; Riis, Jens Ove

2009-01-01

A key problem of manufacturing transfer remains that it is often difficult to explain what a company really knows, or why what it does really works. Still, practice indicates that attention is focused on planning the physical move and on the knowledge associated with normal operations. Introduction...... elements of dispatching capacity and places it in a model in a broader context....

Advanced Manufacturing Technologies (AMT): Modular Rapidly Manufactured SmallSat

Data.gov (United States)

National Aeronautics and Space Administration — Utilize advanced manufacturing processes to design and fabricate a fully functional prototype flight model, with the goal of demonstrating rapid on-orbit assembly of...

Manufacturing Capital Lingers in the Stock Market

Institute of Scientific and Technical Information of China (English)

吴程涛; 段铸; 张景宇; 张曙光

2008-01-01

Pressured by a slowdown in exports, cost increases and dwindling returns to manufacturing investments, China’s manufacturing capital has begun to shift to the real-estate and stock markets. As a matter of fact, the stock market had already felt a shock a couple of years ago when top domestic manufacturers like Midea, Gree, TCL and LMZ started to invest their idle capital in the real-estate and stock markets. Investments of manufacturing capital in both the real estate and stock markets have increased fluid capital and pushed up the value of both markets. Booms in both markets have in turn guaranteed investment returns of manufacturing capital, which further increased the stock market valuations of manufacturing capital. Such a cycle has created interest chains between listed manufacturers, the stock market and the real-estate market. Along with the ups and downs of the stock and real-estate markets, manufacturing capital now faces a dilemma: to escape or to persist? Where should it escape? When can the markets be profitable again? Just like the classic Shakespearean question: to be or not to be, that is the question.

Lean Application to Manufacturing Ramp-Up

DEFF Research Database (Denmark)

Christensen, Irene; Rymaszewska, Anna

2016-01-01

. Abstracting from the extant literature, the authors considered the competitiveness of manufacturing companies from two principal perspectives: the leanness of the ramp-up process and the new-value creation of quality managers. While much of the literature fails to acknowledge that the roots of lean actually......This article provides a theoretical overview of the concepts of lean and manufacturing ramp-up in an attempt to conceptualize the strategic areas in which lean philosophy and principles can be applied for continuous improvements. The application of lean principles during the final stage of a new...... product development process, that is, the ramp-up process, is a critical, early enabler of lean manufacturing. The manufacturing strategy literature conceptualizes a state of “leanness in operations,” which can consolidate both the concepts of lean and manufacturing ramp-up, providing a dual perspective...

Adaptive Process Controls and Ultrasonics for High Temperature PEM MEA Manufacture

Energy Technology Data Exchange (ETDEWEB)

Walczyk, Daniel F. [Rensselaer Polytechnic Inst., Troy, NY (United States)

2015-08-26

The purpose of this 5-year DOE-sponsored project was to address major process bottlenecks associated with fuel cell manufacturing. New technologies were developed to significantly reduce pressing cycle time for high temperature PEM membrane electrode assembly (MEA) through the use of novel, robust ultrasonic (U/S) bonding processes along with low temperature (<100°C) PEM MEAs. In addition, greater manufacturing uniformity and performance was achieved through (a) an investigation into the causes of excessive variation in ultrasonically and thermally bonded MEAs using more diagnostics applied during the entire fabrication and cell build process, and (b) development of rapid, yet simple quality control measurement techniques for use by industry.

Manufacturing of a HCLL cooling plate mock up

International Nuclear Information System (INIS)

Rigal, E.; Dinechin, G. de; Rampal, G.; Laffont, G.; Cachon, L.

2007-01-01

The European DEMO blankets and associated Test Blanket Modules (TBM) are made of a set of components cooled by flowing helium at 80bar pressure. Hot Isostatic Pressing (HIP) is one of the very few processes that allow manufacturing such components exhibiting complex cooling channels. In HIP technology, the parts used to manufacture components with embedded channels are usually machined plates, blocks and tubes. Achievable geometries are limited in shape because it is not always possible to figure the channels by bent tubes. This occurs for example when channels present sharp turns, when the cross section of the channels is rectangular or when the rib between channels is so small that very thin tubes would be required. In these cases, bending is unpractical. The breeder unit cooling plates of the Helium Cooled Lithium Lead (HCLL) blanket have eight 4 x 4.5 mm parallel channels that run following a double U scheme. Turns are sharp and the wall thickness is small (1mm), so the manufacturing process described above cannot be used. An alternative process has been developed which has many advantages. It consists in machining grooves in a base plate, then closing the top of the grooves using thin welded strips, and finally adding a plate by HIP. There is then no need for the use of tubes with associated bending and deformation issues. The final component contains welds, but it must be stressed out that these potentially brittle zones do not connect the channels to the external surface because they are covered by the HIPed plate. Furthermore, the welds are homogenised during the HIP operation and further heat treatments. This paper describes the design of a simplified cooling plate mock up and its fabrication using this so-called weld+HIP process. The thermal fatigue testing of this mock up is presented somewhere else in this conference. (orig.)

Design and additive manufacture for flow chemistry.

Science.gov (United States)

Capel, Andrew J; Edmondson, Steve; Christie, Steven D R; Goodridge, Ruth D; Bibb, Richard J; Thurstans, Matthew

2013-12-07

We review the use of additive manufacturing (AM) as a novel manufacturing technique for the production of milli-scale reactor systems. Five well-developed additive manufacturing techniques: stereolithography (SL), multi-jet modelling (MJM), selective laser melting (SLM), laser sintering (LS) and fused deposition modelling (FDM) were used to manufacture a number of miniaturised reactors which were tested using a range of organic and inorganic reactions.

Design, Development and Hotfire Testing of Monolithic Copper and Bimetallic Additively Manufactured Combustion Chambers

Science.gov (United States)

Gradl, Paul; Barnett, Greg; Brandsmeier, Will; Greene, Sandy Elam; Protz, Chris

2016-01-01

NASA and industry partners are working towards fabrication process development to reduce costs and schedules associated with manufacturing liquid rocket engine components with the goal of reducing overall mission costs. One such technique being evaluated is powder-bed fusion or selective laser melting (SLM) otherwise commonly referred to as additive manufacturing. The NASA Low Cost Upper Stage Propulsion (LCUSP) program was designed to develop processes and material characterization for the GRCop-84 copper-alloy commensurate with powder bed additive manufacturing, evaluate bimetallic deposition and complete testing of a full scale combustion chamber. As part of this development, the process has been transferred to industry partners to enable a long-term supply chain of monolithic copper combustion chambers. As a direct spin off of this program, NASA is working with industry partners to further develop the printing process for the GRCop-84 material in addition to the C-18150 (CuCrZr) material. To advance the process further and allow for optimization with multiple materials, NASA is also investigating the feasibility of bimetallic additively manufactured chambers. A 1.2k sized thrust-chamber was designed and developed to compare the printing process of the GRCop-84 and C-18150 SLM materials. A series of similar MCC liners also completed development with an Inconel 625 jacket bonded to the GRcop-84 liner evaluating direct metal deposition (DMD) laser and arc-based techniques. This paper describes the design, development, manufacturing and testing of these combustion chambers and associated lessons learned throughout the design and development process.

Effort levels of the partners in networked manufacturing

Science.gov (United States)

Chai, G. R.; Cai, Z.; Su, Y. N.; Zong, S. L.; Zhai, G. Y.; Jia, J. H.

2017-08-01

Compared with traditional manufacturing mode, could networked manufacturing improve effort levels of the partners? What factors will affect effort level of the partners? How to encourage the partners to improve their effort levels? To answer these questions, we introduce network effect coefficient to build effort level model of the partners in networked manufacturing. The results show that (1) with the increase of the network effect in networked manufacturing, the actual effort level can go beyond the ideal level of traditional manufacturing. (2) Profit allocation based on marginal contribution rate would help improve effort levels of the partners in networked manufacturing. (3) The partners in networked manufacturing who wishes to have a larger distribution ratio must make a higher effort level, and enterprises with insufficient effort should be terminated in networked manufacturing.

Investigating broadband acoustic adsorption using rapid manufacturing

Science.gov (United States)

Godbold, O.

The reduction of nuisance noise and the removal of unwanted sound modes within a room or component enclosure-area can be accomplished through the use of acoustic absorbers. Sound absorption can be achieved through conversion of the kinetic energy associated with pressure waves, into heat energy via viscous dissipation. This occurs within open porous materials, or by utilising resonant effects produced using simple cavity and orifice configurations. The manufacture of traditional porous and resonant absorbers is commonly realised using basic manufacturing techniques. These techniques restrict the geometry of a given resonant construction, and limit the configuration of porous absorbers. The aim of this work is to exploit new and emerging capabilities of Rapid Manufacturing (RM) to produce components with geometrical freedom, and apply it to the development of broadband acoustic absorption. New and novel absorber geometric configurations are identified and their absorption performance is determined. The capabilities and limitations of RM processes in reproducing these configurations are demonstrated. The geometric configuration of RM resonant absorbers is investigated. Cavity modifications aimed at damping the resonant effect by restricting the motion of cavity air, and adding increased viscous resistance are explored. Modifications relating to cavity shape, the addition of internal perforations and increased cavity surface area have all been shown to add acoustic resistance, thereby increasing the bandwidth of absorption. Decreasing the hydraulic radius of the cavity cross section and reducing internal feature dimensions provide improved resistance over conventional configurations..

Manufacturing mobility in global operations

NARCIS (Netherlands)

Steenhuis, H.J.; de Bruijn, E.J.

2002-01-01

The globalization trend inevitably affects the organization of manufacturing by enterprises. It offers opportunities to examine manufacturing from a global perspective and consequently to produce where it is most appropriate. However, globalization has also led to an increase in competitive

Handbook of manufacturing engineering and technology

CERN Document Server

2015-01-01

The Springer Reference Work Handbook of Manufacturing Engineering and Technology provides overviews and in-depth and authoritative analyses on the basic and cutting-edge manufacturing technologies and sciences across a broad spectrum of areas. These topics are commonly encountered in industries as well as in academia. Manufacturing engineering curricula across universities are now essential topics covered in major universities worldwide.

Energy-climate-manufacturing nexus: New insights from the regional and global supply chains of manufacturing industries

International Nuclear Information System (INIS)

Kucukvar, Murat; Cansev, Bunyamin; Egilmez, Gokhan; Onat, Nuri C.; Samadi, Hamidreza

2016-01-01

Highlights: • A multi region input–output sustainability assessment model is developed. • Energy-climate-manufacturing nexus within the context of global supply chains is investigated. • Electricity, Gas, and Water Supply sector is the main contributor to energy and carbon impacts. • Turkish regional manufacturing accounts for approximately 40–60% of total carbon emissions. • China, USA, and Rest-of-the World have the largest shares in the Turkish global energy footprint. - Abstract: The main objectives of this research are to improve our understanding of energy-climate-manufacturing nexus within the context of regional and global manufacturing supply chains as well as show the significance of full coverage of entire supply chain tiers in order to prevent significant underestimations, which might lead to invalid policy conclusions. With this motivation, a multi region input–output (MRIO) sustainability assessment model is developed by using the World Input–Output Database, which is a dynamic MRIO framework on the world’s 40 largest economies covering 1440 economic sectors. The method presented in this study is the first environmentally-extended MRIO model that harmonizes energy and carbon footprint accounts for Turkish manufacturing sectors and a global trade-linked carbon and energy footprint analysis of Turkish manufacturing sectors is performed as a case study. The results are presented by distinguishing the contributions of five common supply chain phases such as upstream suppliers, onsite manufacturing, transportation, wholesale, and retail trade. The findings showed that onsite and upstream supply chains are found to have over 90% of total energy use and carbon footprint for all industrial sectors. Electricity, Gas and Water Supply sector is usually found to be as the main contributor to global climate change, and Coke, Refined Petroleum, and Nuclear Fuel sector is the main driver of energy use in upstream supply chains. Overall, the

The manufacturing blueprint environment : Bringing intelligence into manufacturing

NARCIS (Netherlands)

Papazoglou, Mike; Elgammal, Amal

Manufacturers today are rapidly moving into a business climate that is characterized by the ability to fulfill orders on demand by doing business through short-term networks where they negotiate value-adding processes dynamically – taking into account quality, time, price, viability, sustainability,

Measurement of sustainability index among paper manufacturing plants

Science.gov (United States)

Sharathkumar Reddy, V.; Jayakrishna, K.; Lal, Babu

2017-11-01

The paper manufacturing companies are facing challenges to implement sustainable manufacturing into their products and processes. Paper manufacturing has remarked as an intensive consumer of natural raw materials, energy and a major source of multiple pollutants. Thus, evaluating the sustainable manufacturing in these companies has become a necessity. This paper proposes a set of Performance Indicators (PIs) for evaluating the sustainable manufacturing appropriate to the paper manufacturing companies based on the triple bottom line of sustainability. The Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS), a multi-criteria decision analysis method is applied to prioritize the performance indicators by summarizing the opinions of stakeholders. It is hoped that the proposed PIs enables and assists the paper manufacturing companies to achieve the higher performance in sustainable manufacturing and so as to increase their competitiveness.

Acquiring energy savings in manufactured housing

International Nuclear Information System (INIS)

Davey, D.

1993-01-01

In 1991, the Northwest utilities faced a complex situation. They needed new sources of electrical power to avoid future deficits. A significant block of energy savings was available in the manufactured housing sector in the form of energy savings from increased insulation to new manufactured homes. The manufacturers were interested in saving the electricity in the homes, but would only deal with the utility sector as a whole. Half of the homes targeted were sited in investor-owned utility (IOU) service territories, and half in the public sector made up of utilities that purchased some or all of their electricity from the Bonneville Power Administration. Utilities agreed to acquire energy from manufacturers In the form of thermal efficiency measures specified by the Bonneville Power Administration. The program that resulted from over one year of negotiations was called the Manufactured Housing Acquisition Program, or MAP. Manufacturers, the utilities, State Energy Offices, the Northwest Power Planning Council and Bonneville all worked closely and with tenacity to build the program that went into effect on April 1, 1992, and should save the region between 7 and 9 megawatts, enough energy to supply 11,000 homes in the Northwest

DECOMPOSITION OF MANUFACTURING PROCESSES: A REVIEW

Directory of Open Access Journals (Sweden)

N.M.Z.N. Mohamed

2012-06-01

Full Text Available Manufacturing is a global activity that started during the industrial revolution in the late 19th century to cater for the large-scale production of products. Since then, manufacturing has changed tremendously through the innovations of technology, processes, materials, communication and transportation. The major challenge facing manufacturing is to produce more products using less material, less energy and less involvement of labour. To face these challenges, manufacturing companies must have a strategy and competitive priority in order for them to compete in a dynamic market. A review of the literature on the decomposition of manufacturing processes outlines three main processes, namely: high volume, medium volume and low volume. The decomposition shows that each sub process has its own characteristics and depends on the nature of the firm’s business. Two extreme processes are continuous line production (fast extreme and project shop (slow extreme. Other processes are in between these two extremes of the manufacturing spectrum. Process flow patterns become less complex with cellular, line and continuous flow compared with jobbing and project. The review also indicates that when the product is high variety and low volume, project or functional production is applied.

Improvement in the reliability of shells for light water reactors by manufacturing from hollow ingots

International Nuclear Information System (INIS)

Bocquet, P.; Blondeau, R.; Poitrault, I.; Badeau, J.P.; Dumont, R.

1989-01-01

The example of forging shells for PWR type reactors is proposed to show how the choice of the manufacturing process may be of prime importance for the component integrity by the reduction of the detrimental effects of segregations. The forging shells (20MnMoNi55) manufactured from hollow ingot are free of any segregation in the critical area located just at the internal surface and sub-surface. Manufacturing problems associated to these segregations in shells issued from conventional ingots, in particular welding difficulties for cladding, have been reduced or eleminated. The reliability of these components present an improved resistance to irradiation embrittlement. (DG)

Economic benefits of metrology in manufacturing

DEFF Research Database (Denmark)

Savio, Enrico; De Chiffre, Leonardo; Carmignato, S.

2016-01-01

examples from industrial production, in which the added value of metrology in manufacturing is discussed and quantified. Case studies include: general manufacturing, forging, machining, and related metrology. The focus of the paper is on the improved effectiveness of metrology when used at product...... and process design stages, as well as on the improved accuracy and efficiency of manufacturing through better measuring equipment and process chains with integrated metrology for process control.......In streamlined manufacturing systems, the added value of inspection activities is often questioned, and metrology in particular is sometimes considered only as an avoidable expense. Documented quantification of economic benefits of metrology is generally not available. This work presents concrete...

Harnessing the Potential of Additive Manufacturing

Science.gov (United States)

2016-12-01

31 Defense AT&L: November-December 2016 Harnessing the Potential of Additive Manufacturing Bill Decker Decker is director of Technology...achieve its goal of competition throughout the acquisition life cycle. When we look at additive manufacturing , we have a much different environment. To...Titanium-6 Aluminum-4 Vanadium with Powder Bed Fusion. This specification covers additively manufactured titanium-6 aluminum-4 vanadium (Ti-6Al-4V

Exploring sustainable manufacturing principles and practices

OpenAIRE

Alayón, Claudia

2016-01-01

The manufacturing industry remains a critical force in the quest for global sustainability. An increasing number of companies are modifying their operations in favor of more sustainable practices. It is hugely important that manufacturers, irrespective of the subsector they belong to, or their organizational size, implement practices that reduce or eliminate negative environmental, social and economic impacts generated by their manufacturing operations. Consequently, scholars have called for ...

Handbook for Small-Scale Densified Biomass Fuel (Pellets) Manufacturing for Local Markets.

Energy Technology Data Exchange (ETDEWEB)

Folk, Richard L.; Govett, Robert L.

1992-07-01

Wood pellet manufacturing in the Intermountain West is a recently founded and rapidly expanding energy industry for small-scale producers. Within a three-year period, the total number of manufacturers in the region has increased from seven to twelve (Folk et al., 1988). Small-scale industry development is evolving because a supply of raw materials from small and some medium-sized primary and secondary wood processors that has been largely unused. For the residue producer considering pellet fuel manufacturing, the wastewood generated from primary products often carries a cost associated with residue disposal when methods at-e stockpiling, landfilling or incinerating. Regional processors use these methods for a variety of reasons, including the relatively small amounts of residue produced, residue form, mixed residue types, high transportation costs and lack of a local market, convenience and absence of regulation. Direct costs associated with residue disposal include the expenses required to own and operate residue handling equipment, costs for operating and maintaining a combustor and tipping fees charged to accept wood waste at public landfills. Economic and social costs related to environmental concerns may also be incurred to include local air and water quality degradation from open-air combustion and leachate movement into streams and drinking water.

Training for New Manufacturing Technologies.

Science.gov (United States)

Jacobs, James

1988-01-01

Examines the effects of computer-based manufacturing technologies on employment opportunities and job skills. Describes the establishment of the Industrial Technology Institute in Michigan to develop and utilize advanced manufacturing technologies, and the institute's relationship to the state's community colleges. Reviews lessons learned from…

75 FR 30781 - Manufacturing Council

Science.gov (United States)

2010-06-02

... convenience. Pending applicants remain under consideration and do not need to resubmit their applications..., particularly seeking the representation of small- and medium-sized enterprises. Additional factors which may be... marketing programs in support of manufacturing industries, job creation in the manufacturing sector, or the...

Robotics in space-age manufacturing

Science.gov (United States)

Jones, Chip

1991-01-01

Robotics technologies are developed to improve manufacturing of space hardware. The following applications of robotics are covered: (1) welding for the space shuttle and space station Freedom programs; (2) manipulation of high-pressure water for shuttle solid rocket booster refurbishment; (3) automating the application of insulation materials; (4) precision application of sealants; and (5) automation of inspection procedures. Commercial robots are used for these development programs, but they are teamed with advanced sensors, process controls, and computer simulation to form highly productive manufacturing systems. Many of the technologies are also being actively pursued in private sector manufacturing operations.

ENABLING SMART MANUFACTURING TECHNOLOGIES FOR DECISION-MAKING SUPPORT

Science.gov (United States)

Helu, Moneer; Libes, Don; Lubell, Joshua; Lyons, Kevin; Morris, KC

2017-01-01

Smart manufacturing combines advanced manufacturing capabilities and digital technologies throughout the product lifecycle. These technologies can provide decision-making support to manufacturers through improved monitoring, analysis, modeling, and simulation that generate more and better intelligence about manufacturing systems. However, challenges and barriers have impeded the adoption of smart manufacturing technologies. To begin to address this need, this paper defines requirements for data-driven decision making in manufacturing based on a generalized description of decision making. Using these requirements, we then focus on identifying key barriers that prevent the development and use of data-driven decision making in industry as well as examples of technologies and standards that have the potential to overcome these barriers. The goal of this research is to promote a common understanding among the manufacturing community that can enable standardization efforts and innovation needed to continue adoption and use of smart manufacturing technologies. PMID:28649678

Delivering Value In A Global Aerospace Manufacturer Through The Effective Use Of Numerical Process Simulation

Science.gov (United States)

Ward, M. J.; Walløe, S. J.

2004-06-01

Numerical models are used extensively in the aerospace sector to identify appropriate manufacturing parameters, and to minimize the risk associated with new product introduction and manufacturing change. This usage is equally prevalent in original equipment manufacturers (OEMs), and in their supply chains. The wide range of manufacturing processes and production environments involved, coupled with the varying degrees of technology maturity associated with numerical models of different processes leads to a situation of significant complexity from the OEM perspective. In addition, the intended use of simulation technology can vary considerably between applications, from simple geometric assessment of die shape at one extreme, to full process design or development at the other. Consequently there is an increasing trend towards multi-scale modelling, i.e. the use of several different model types, with differing attributes in terms of accuracy and speed to support a range of different new product introduction decisions. This makes the allocation of appropriate levels of activity to the research and implementation of new capabilities a difficult problem. This paper uses a number of industrial cases studies to illustrate a framework for making such allocation decisions such that value to the OEM is maximized, and investigates how such a framework is likely to shift over the next few years based on technological developments.

On the Path to SunShot. Emerging Opportunities and Challenges in U.S. Solar Manufacturing

Energy Technology Data Exchange (ETDEWEB)

Chung, Donald [National Renewable Energy Lab. (NREL), Golden, CO (United States); Horowitz, Kelsey [National Renewable Energy Lab. (NREL), Golden, CO (United States); Kurup, Parthiv [National Renewable Energy Lab. (NREL), Golden, CO (United States)

2016-05-01

This report provides insights into photovoltaic (PV) and concentrating solar power (CSP) manufacturing in the context of the U.S. Department of Energy's SunShot Initiative. Although global PV price reductions and deployment have been strong recently, PV manufacturing faces challenges. Slowing rates of manufacturing cost reductions, combined with the relatively low price of incumbent electricity generating sources in most large global PV markets, may constrain profit opportunities for firms and poses a potential challenge to the sustainable operation and growth of the global PV manufacturing base. In the United States, manufacturers also face a factors-of-production cost disadvantage compared with competing nations. However, the United States is one of the world's most competitive and innovative countries as well as one of the best locations for PV manufacturing. In conjunction with strong projected PV demand in the United States and across the Americas, these advantages could increase the share of PV technologies produced by U.S. manufacturers as the importance of innovation-driven PV cost reductions increases. Compared with PV, CSP systems are much more complex and require a much larger minimum effective scale, resulting in much higher total CAPEX requirements for system construction, lengthier development cycles, and ultimately higher costs of energy produced. The global lack of consistent CSP project development creates challenges for companies that manufacture specialty CSP components, and the potential lack of a near-term U.S. market could hinder domestic CSP manufacturers. However, global and U.S. CSP deployment is expected to expand beyond 2020, and U.S. CSP manufacturers could benefit from U.S. innovation advantages similar to those associated with PV. Expansion of PV and CSP manufacturing also presents U.S. job-growth opportunities.

Test manufacture of a canister insert

International Nuclear Information System (INIS)

Raiko, H.

2004-11-01

This report describes the insert-manufacturing test of a disposal canister for spent nuclear fuel that was made by Metso Paper Oy, Jyvaeskylae Foundry, in 2003 on contract for Posiva Oy. The test manufacture was a part of the co-operation development programme of encapsulation technology between SKB AB and Posiva Oy. Insert casting was specified according to the current manufacturing specifications of SKB. The canister insert was of BWR-type with integral bottom. This was the first trial manufacture of this type of insert in Finland and, in total, the second test manufacture of insert by Metso Paper. The result fulfilled all the requirements but the material mechanical properties and metallurgical structure of the cast material. The measured tensile strength, ultimate strength and elongation at rupture were lower than specified. The reason for this was revealed in the metallurgical investigation of the cast material. The nodulizing of the graphite was not occurred during the casting process according to the requirements. (orig.)

Role of Ontologies for CPS Implementation in Manufacturing

Directory of Open Access Journals (Sweden)

Garetti Marco

2015-12-01

Full Text Available Cyber Physical Systems are an evolution of embedded systems featuring a tight combination of collaborating computational elements that control physical entities. CPSs promise a great potential of innovation in many areas including manufacturing and production. This is because we obtain a very powerful, flexible, modular infrastructure allowing easy (re configurability and fast ramp-up of manufacturing applications by building a manufacturing system with modular mechatronic components (for machining, transportation and storage and embedded intelligence, by integrating them into a system, through a network connection. However, when building such kind of architectures, the way to supply the needed domain knowledge to real manufacturing applications arises as a problem to solve. In fact, a CPS based architecture for manufacturing is made of smart but independent manufacturing components without any knowledge of the role they have to play together in the real world of manufacturing applications. Ontologies can supply such kind of knowledge, playing a very important role in CPS for manufacturing. The paper deals with this intriguing theme, also presenting an implementation of this approach in a research project for the open automation of manufacturing systems, in which the power of CPS is complemented by the support of an ontology of the manufacturing domain.

Advances in the manufacture of MIP nanoparticles.

Science.gov (United States)

Poma, Alessandro; Turner, Anthony P F; Piletsky, Sergey A

2010-12-01

Molecularly imprinted polymers (MIPs) are prepared by creating a three-dimensional polymeric matrix around a template molecule. After the matrix is removed, complementary cavities with respect to shape and functional groups remain. MIPs have been produced for applications in in vitro diagnostics, therapeutics and separations. However, this promising technology still lacks widespread application because of issues related to large-scale production and optimization of the synthesis. Recent developments in the area of MIP nanoparticles might offer solutions to several problems associated with performance and application. This review discusses various approaches used in the preparation of MIP nanoparticles, focusing in particular on the issues associated with large-scale manufacture and implications for the performance of synthesized nanomaterials. Copyright © 2010 Elsevier Ltd. All rights reserved.

CANDU fuel : design/manufacturing interaction

International Nuclear Information System (INIS)

Graham, N.A.

1999-01-01

The design of CANDU fuel has been the product of intense cooperation among fuel designers and fuel manufacturers. The developments of some of the novel processes in fuel manufacture are outlined. These include the brazed-split-spacer design, the resistance welded endcap and CANLUB coatings. (author)

Virtual manufacturing in reality

Science.gov (United States)

Papstel, Jyri; Saks, Alo

2000-10-01

SMEs play an important role in manufacturing industry. But from time to time there is a shortage in resources to complete the particular order in time. Number of systems is introduced to produce digital information in order to support product and process development activities. Main problem is lack of opportunity for direct data transition within design system modules when needed temporary extension of design capacity (virtuality) or to implement integrated concurrent product development principles. The planning experience in the field is weakly used as well. The concept of virtual manufacturing is a supporting idea to solve this problem. At the same time a number of practical problems should be solved like information conformity, data transfer, unified technological concepts acceptation etc. In the present paper the proposed ways to solve the practical problems of virtual manufacturing are described. General objective is to introduce the knowledge-based CAPP system as missing module for Virtual Manufacturing in the selected product domain. Surface-centered planning concept based on STEP- based modeling principles, and knowledge-based process planning methodology will be used to gain the objectives. As a result the planning module supplied by design data with direct access, and supporting advising environment is expected. Mould producing SME would be as test basis.

The use of fatigue tests in the manufacture of automotive steel wheels.

Science.gov (United States)

Drozyner, P.; Rychlik, A.

2016-08-01

Production for the automotive industry must be particularly sensitive to the aspect of safety and reliability of manufactured components. One of such element is the rim, where durability is a feature which significantly affects the safety of transport. Customer complaints regarding this element are particularly painful for the manufacturer because it is almost always associated with the event of accident or near-accident. Authors propose original comprehensive method of quality control at selected stages of rims production: supply of materials, production and pre-shipment inspections. Tests by the proposed method are carried out on the originally designed inertial fatigue machine The machine allows bending fatigue tests in the frequency range of 0 to 50 Hz at controlled increments of vibration amplitude. The method has been positively verified in one of rims factory in Poland. Implementation resulted in an almost complete elimination of complaints resulting from manufacturing and material errors.

Manufacturing: the new case for vertical integration

NARCIS (Netherlands)

Kumpe, Ted; Bolwijn, Piet

1988-01-01

The article argues that the solid corporation will continue to view vertical integration as a critical part of manufacturing reform. Manufacturing reform and backward integration are related in insidious ways to the three stages of production over which the big manufacturers preside. Without

Manufacturing Process Simulation of Large-Scale Cryotanks

Science.gov (United States)

Babai, Majid; Phillips, Steven; Griffin, Brian

2003-01-01

NASA's Space Launch Initiative (SLI) is an effort to research and develop the technologies needed to build a second-generation reusable launch vehicle. It is required that this new launch vehicle be 100 times safer and 10 times cheaper to operate than current launch vehicles. Part of the SLI includes the development of reusable composite and metallic cryotanks. The size of these reusable tanks is far greater than anything ever developed and exceeds the design limits of current manufacturing tools. Several design and manufacturing approaches have been formulated, but many factors must be weighed during the selection process. Among these factors are tooling reachability, cycle times, feasibility, and facility impacts. The manufacturing process simulation capabilities available at NASA.s Marshall Space Flight Center have played a key role in down selecting between the various manufacturing approaches. By creating 3-D manufacturing process simulations, the varying approaches can be analyzed in a virtual world before any hardware or infrastructure is built. This analysis can detect and eliminate costly flaws in the various manufacturing approaches. The simulations check for collisions between devices, verify that design limits on joints are not exceeded, and provide cycle times which aide in the development of an optimized process flow. In addition, new ideas and concerns are often raised after seeing the visual representation of a manufacturing process flow. The output of the manufacturing process simulations allows for cost and safety comparisons to be performed between the various manufacturing approaches. This output helps determine which manufacturing process options reach the safety and cost goals of the SLI. As part of the SLI, The Boeing Company was awarded a basic period contract to research and propose options for both a metallic and a composite cryotank. Boeing then entered into a task agreement with the Marshall Space Flight Center to provide manufacturing

An implementation framework for additive manufacturing in supply chains

Directory of Open Access Journals (Sweden)

Raed Handal

2017-12-01

Full Text Available Additive manufacturing has become one of the most important technologies in the manufacturing field. Full implementation of additive manufacturing will change many well-known management practices in the production sector. However, theoretical development in the field of additive manufacturing with regard to its impact on supply chain management is rare. While additive manufacturing is believed to revolutionize and enhance traditional manufacturing, there is no comprehensive toolset developed in the manufacturing field to assess the impact of additive manufacturing and determine the best production method that suits the applied supply chain strategy. A significant portion of the existing supply chain methods and frameworks were adopted in this study to examine the implementation of additive manufacturing in supply chain management. The aim of this study is to develop a framework to explain when additive manufacturing impacts supply chain management efficiently.

Manufacturing strategies for time based competitive advantages

OpenAIRE

Lin, Yong; Ma, Shihua; Zhou, Li

2012-01-01

Purpose – The main purpose of this paper is to investigate the current manufacturing strategies and practices of bus manufacturers in China, and to propose a framework of manufacturing strategies for time-based competitive advantages.\\ud Design/methodology/approach – The conceptual research framework is devised from a review of the literature, and case studies are used to investigate the manufacturing strategies and practices in place in the case companies. Data is collected through semi-stru...

21 CFR 110.5 - Current good manufacturing practice.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Current good manufacturing practice. 110.5 Section...) FOOD FOR HUMAN CONSUMPTION CURRENT GOOD MANUFACTURING PRACTICE IN MANUFACTURING, PACKING, OR HOLDING HUMAN FOOD General Provisions § 110.5 Current good manufacturing practice. (a) The criteria and...

Measure of manufacturing performance in advanced manufacturing systems

NARCIS (Netherlands)

Ron, de A.J.

1995-01-01

Because of the financial risks as a result of the high investments, decisions concerning investing in advanced manufacturing systems are difficult. The difficulty to decide is gained by the lack of a well-defined measure to support decisions and alarming messages from the industry concerning inverse

Bio-Manufacturing to market pilot project

Energy Technology Data Exchange (ETDEWEB)

Dressen, Tiffaney [Univ. of California, Berkeley, CA (United States)

2017-09-25

The Bio-Manufacturing to Market pilot project was a part of the AMJIAC, the Advanced Manufacturing Jobs and Innovation Accelerator Challenge grant. This internship program set out to further define and enhance the talent pipeline from the University and local Community Colleges to startup culture in East Bay Area, provide undergraduate STEM students with opportunities outside academia, and provide startup companies with much needed talent. Over the 4 year period of performance, the Bio-Manufacturing to Market internship program sponsored 75 undergraduate STEM students who were able to spend anywhere from one to six semesters working with local Bay Area startup companies and DOE sponsored facilities/programs in the biotech, bio-manufacturing, and biomedical device fields.

Advance Manufacturing Office FY 2017 Budget At-A-Glance

Energy Technology Data Exchange (ETDEWEB)

None

2016-03-01

The Advanced Manufacturing Office (AMO) brings together manufacturers, research institutions, suppliers, and universities to investigate manufacturing processes, information, and materials technologies critical to advance domestic manufacturing of clean energy products, and to support energy productivity across the entire manufacturing sector.

Integrating Materials, Manufacturing, Design and Validation for Sustainability in Future Transport Systems

International Nuclear Information System (INIS)

Price, M. A.; Murphy, A.; Butterfield, J.; McCool, R.; Fleck, R.

2011-01-01

The predictive methods currently used for material specification, component design and the development of manufacturing processes, need to evolve beyond the current 'metal centric' state of the art, if advanced composites are to realise their potential in delivering sustainable transport solutions. There are however, significant technical challenges associated with this process. Deteriorating environmental, political, economic and social conditions across the globe have resulted in unprecedented pressures to improve the operational efficiency of the manufacturing sector generally and to change perceptions regarding the environmental credentials of transport systems in particular. There is a need to apply new technologies and develop new capabilities to ensure commercial sustainability in the face of twenty first century economic and climatic conditions as well as transport market demands. A major technology gap exists between design, analysis and manufacturing processes in both the OEMs, and the smaller companies that make up the SME based supply chain. As regulatory requirements align with environmental needs, manufacturers are increasingly responsible for the broader lifecycle aspects of vehicle performance. These include not only manufacture and supply but disposal and re-use or re-cycling. In order to make advances in the reduction of emissions coupled with improved economic efficiency through the provision of advanced lightweight vehicles, four key challenges are identified as follows: Material systems, Manufacturing systems, Integrated design methods using digital manufacturing tools and Validation systems. This paper presents a project which has been designed to address these four key issues, using at its core, a digital framework for the creation and management of key parameters related to the lifecycle performance of thermoplastic composite parts and structures. It aims to provide capability for the proposition, definition, evaluation and demonstration of

Integrating Materials, Manufacturing, Design and Validation for Sustainability in Future Transport Systems

Science.gov (United States)

Price, M. A.; Murphy, A.; Butterfield, J.; McCool, R.; Fleck, R.

2011-05-01

The predictive methods currently used for material specification, component design and the development of manufacturing processes, need to evolve beyond the current `metal centric' state of the art, if advanced composites are to realise their potential in delivering sustainable transport solutions. There are however, significant technical challenges associated with this process. Deteriorating environmental, political, economic and social conditions across the globe have resulted in unprecedented pressures to improve the operational efficiency of the manufacturing sector generally and to change perceptions regarding the environmental credentials of transport systems in particular. There is a need to apply new technologies and develop new capabilities to ensure commercial sustainability in the face of twenty first century economic and climatic conditions as well as transport market demands. A major technology gap exists between design, analysis and manufacturing processes in both the OEMs, and the smaller companies that make up the SME based supply chain. As regulatory requirements align with environmental needs, manufacturers are increasingly responsible for the broader lifecycle aspects of vehicle performance. These include not only manufacture and supply but disposal and re-use or re-cycling. In order to make advances in the reduction of emissions coupled with improved economic efficiency through the provision of advanced lightweight vehicles, four key challenges are identified as follows: Material systems, Manufacturing systems, Integrated design methods using digital manufacturing tools and Validation systems. This paper presents a project which has been designed to address these four key issues, using at its core, a digital framework for the creation and management of key parameters related to the lifecycle performance of thermoplastic composite parts and structures. It aims to provide capability for the proposition, definition, evaluation and demonstration of

Additive Manufacturing Cloud via Peer-Robot Collaboration

Directory of Open Access Journals (Sweden)

Yuan Yao

2016-05-01

Full Text Available When building a 3D printing cloud manufacturing platform, self-sensing and collaboration on manufacturing resources present challenging problems. This paper proposes a peer-robot collaboration framework to deal with these issues. Each robot combines heterogeneous additive manufacturing hardware and software, acting as an intelligent agent. Through collaboration with other robots, it forms a dynamic and scalable integration manufacturing system. The entire distributed system is managed by rules that employ an internal rule engine, which supports rule conversion and conflict resolution. Two additive manufacturing service scenarios are designed to analyse the efficiency and scalability of the framework. Experiments show that the presented method performs well in tasks requiring large-scale access to resources and collaboration.

Trial of Engineer Educating of Manufacturing Field in Kagoshima National College of Technology

Science.gov (United States)

Nakamura, Itaru; Hombu, Mitsuyuki; Kusuhara, Yoshito; Kashine, Kenji; Sakasegawa, Eiichi; Tashima, Daisuke; Fukidome, Hiromi

In Kagoshima National College of Technology, based on investigation with “the job boost measure investigation work in a power supply area” undertaken in the 2005 fiscal year, we accepted the trust from Kyushu Bureau of Economy, Trade and Industry, and undertook “the small-and-medium-sized-enterprises personnel educating work which utilized the technical college etc.” for three years from the 2006 fiscal year to the 2008 fiscal year. As the trial of engineer educating according to the electrical engineering concept to the manufacturing field based on a conventional result, we act as a professor of the base technique for applying alternative energy (a fuel cell and a solar cell) in which social needs are powerful these days, and aim at aiming at cultivation of the problem-solving type engineer who can contribute to a low carbon society through manufacturing, we undertook this work according to the manufacturing bearer educating work (personnel educating and secured work of the manufacturing field) in the 2009 fiscal year of National Federation of Small Business Associations.

Validated Feasibility Study of Integrally Stiffened Metallic Fuselage Panels for Reducing Manufacturing Costs

Science.gov (United States)

Pettit, R. G.; Wang, J. J.; Toh, C.

2000-01-01

The continual need to reduce airframe cost and the emergence of high speed machining and other manufacturing technologies has brought about a renewed interest in large-scale integral structures for aircraft applications. Applications have been inhibited, however, because of the need to demonstrate damage tolerance, and by cost and manufacturing risks associated with the size and complexity of the parts. The Integral Airframe Structures (IAS) Program identified a feasible integrally stiffened fuselage concept and evaluated performance and manufacturing cost compared to conventional designs. An integral skin/stiffener concept was produced both by plate hog-out and near-net extrusion. Alloys evaluated included 7050-T7451 plate, 7050-T74511 extrusion, 6013-T6511 extrusion, and 7475-T7351 plate. Mechanical properties, structural details, and joint performance were evaluated as well as repair, static compression, and two-bay crack residual strength panels. Crack turning behavior was characterized through panel tests and improved methods for predicting crack turning were developed. Manufacturing cost was evaluated using COSTRAN. A hybrid design, made from high-speed machined extruded frames that are mechanically fastened to high-speed machined plate skin/stringer panels, was identified as the most cost-effective manufacturing solution. Recurring labor and material costs of the hybrid design are up to 61 percent less than the current technology baseline.

48 CFR 52.225-18 - Place of Manufacture.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Place of Manufacture. 52....225-18 Place of Manufacture. As prescribed in 25.1101(f), insert the following solicitation provision: Place of Manufacture (SEP 2006) (a) Definitions. As used in this clause— Manufactured end product means...

Additive Manufacturing: Unlocking the Evolution of Energy Materials.

Science.gov (United States)

Zhakeyev, Adilet; Wang, Panfeng; Zhang, Li; Shu, Wenmiao; Wang, Huizhi; Xuan, Jin

2017-10-01

The global energy infrastructure is undergoing a drastic transformation towards renewable energy, posing huge challenges on the energy materials research, development and manufacturing. Additive manufacturing has shown its promise to change the way how future energy system can be designed and delivered. It offers capability in manufacturing complex 3D structures, with near-complete design freedom and high sustainability due to minimal use of materials and toxic chemicals. Recent literatures have reported that additive manufacturing could unlock the evolution of energy materials and chemistries with unprecedented performance in the way that could never be achieved by conventional manufacturing techniques. This comprehensive review will fill the gap in communicating on recent breakthroughs in additive manufacturing for energy material and device applications. It will underpin the discoveries on what 3D functional energy structures can be created without design constraints, which bespoke energy materials could be additively manufactured with customised solutions, and how the additively manufactured devices could be integrated into energy systems. This review will also highlight emerging and important applications in energy additive manufacturing, including fuel cells, batteries, hydrogen, solar cell as well as carbon capture and storage.

Manufacturing inspection of electrical steels using Magnetic Barkhausen Noise: residual stress detection

Energy Technology Data Exchange (ETDEWEB)

Samimi, A.A., E-mail: 9aa8@queensu.ca [Queen' s Univ., Applied Magnetics Group, Kingston, Ontario (Canada); Krause, T.W. [Royal Military College of Canada, NDE Lab., Kingston, Ontario (Canada); Clapham, L. [Queen' s Univ., Applied Magnetics Group, Kingston, Ontario (Canada); Gallaugher, M.; Ding, Y.; Chromik, R. [McGill Univ., Dept. of Mining and Materials Engineering, Montreal, Quebec (Canada)

2016-09-15

Non-oriented Electrical Steel (NOES) is the magnetic core lamination material used for flux transfer in rotary machines. The presence of residual stress associated with material processing may be detrimental to magnetic domain structure refinement and as a result, magnetic performance of NOES. Therefore, manufacturing inspection of NOES that identifies the presence of residual stress could contribute to the production of more energy efficient cores. However, standard materials evaluation is limited to destructive and off-line techniques. The present work employed Magnetic Barkhausen Noise (MBN) for nondestructive identification of local residual stress associated with stages in material processing. Analysis of MBN from single strips of NOES demonstrated clear response to applied tensile stress, mechanical shearing, the presence of an insulating coating and punching. The results establish the potential of MBN as a nondestructive testing technology for quality control of electrical steels at various stages of manufacture. (author)

78 FR 18234 - Service of Process on Manufacturers; Manufacturers Importing Electronic Products Into the United...

Science.gov (United States)

2013-03-26

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Part 1005 [Docket No. FDA-2007-N-0091; (formerly 2007N-0104)] Service of Process on Manufacturers; Manufacturers Importing Electronic Products Into the United States; Agent Designation; Change of Address AGENCY: Food and Drug...

Policy Reform Impact on Food Manufacturing

OpenAIRE

Celikkol, Pinar; Dunn, James W.; Stefanou, Spiro E.

2003-01-01

The impact of agricultural policies and their reform is of major concern when addressing issues of growth, innovation and consolidation in the food manufacturing sector. Growth is one of the forces fueling the globalization of food manufacturing activities. Market- and policy-driven forces present a myriad of opportunities to influence growth and reorientation of patterns at the nexus where food manufacturing links the food system. The productivity and international competitiveness of the foo...

Manufacture and maintenance of laboratory equipment

Energy Technology Data Exchange (ETDEWEB)

Hwang, Chang Kyu; Hwang, Bong Ha; Lee, Jong Wha; Kim, Jong Kyun; Yeum, Ki Eon; Park, Myung Ku; Hong, Soon Eon; Choi, Ho Young; An, Dae Kyu; An, Choon; Park, In Won; Kim, Kyung Sik; Lee, Won Jae; Yoon, Ki Byung; Kim, Heung Woo; Lee, In Bae; Yeom, Jeong Hyun; Lee, Chul Ku; Sin, Keon Ju; Oh, Wan Ho; Seo, Yong Chil; Yang, Song Yeul; Lee, Young Soon; Choi, Byung Kwon; Chang, Kyung Duk [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

1993-12-01

This report on the manufacture and maintenance of laboratory equipment contains working contents, scope and contents of request working to the machine shop, also records the principal production design, manufacture contents and a relevant working drawing. The working content and scope of the machine shop is to support the successful and convenient performance of the R and D by manufacture and maintenance of all sorts of laboratory equipment. 11 tabs., 3 figs. (Author) .new.

Manufacture and maintenance of laboratory equipment

International Nuclear Information System (INIS)

Hwang, Chang Kyu; Hwang, Bong Ha; Lee, Jong Wha; Kim, Jong Kyun; Yeum, Ki Eon; Park, Myung Ku; Hong, Soon Eon; Choi, Ho Young; An, Dae Kyu; An, Choon; Park, In Won; Kim, Kyung Sik; Lee, Won Jae; Yoon, Ki Byung; Kim, Heung Woo; Lee, In Bae; Yeom, Jeong Hyun; Lee, Chul Ku; Sin, Keon Ju; Oh, Wan Ho; Seo, Yong Chil; Yang, Song Yeul; Lee, Young Soon; Choi, Byung Kwon; Chang, Kyung Duk

1993-12-01

This report on the manufacture and maintenance of laboratory equipment contains working contents, scope and contents of request working to the machine shop, also records the principal production design, manufacture contents and a relevant working drawing. The working content and scope of the machine shop is to support the successful and convenient performance of the R and D by manufacture and maintenance of all sorts of laboratory equipment. 11 tabs., 3 figs. (Author) .new

Manufacture and maintenance of laboratory equipment

International Nuclear Information System (INIS)

Kim, Jong Kyun; Hwang, Chang Kyu; Hwang, Bong Ha; Lee, Jong Wha; Yeom, Ki Eon; Park, Myung Ku; Hong, Soon Hyeon; Choi, Ho Young; An, Dae Kyu; An, Choon; Park, In Won; Kim, Kyeong Sik; Lee, In Bae; Yeom, Jeong Heon; Lee, Chul Ku; Sin, Keon Ju; Oh, Wan Ho; Choi, Byung Kwon; Chang, Kyeong Duk; Lee, Young Soon

1995-12-01

This report on the manufacture and maintenance of laboratory equipment contains working contents, scope and contents of a request working to the Machine Shop, also records the principal production design, manufacture contents and a relevant working drawing. The working content and scope of the Machine Shop is to support the successful and convenient performance of the Research and development by manufacture and maintenance of all sorts of laboratory equipment. 12 tabs., 5 figs. (Author) .new

Manufacture and maintenance of laboratory equipment

International Nuclear Information System (INIS)

Kim, J. K.; Whang, C. K.; Lee, J. H.; Youm, K. Y.; Hong, S. H.; Choi, H. Y.; An, C.; Park, I. W.; Kim, K. S.; Lee, W. J.; Yoon, K. B.; Kim, H. W.; Lee, I. B.; Lee, C. K.; Youm, J. H.; Oho, W. H.; Choi, B. K.; Jang, K. D.

1996-12-01

This report on the manufacture and maintenance of laboratory equipment contains working contents, scope and contents of a request working to the Machine Shop, also records the principal production design, manufacture contents and a relevant working drawing. The working content and scope of the Machine Shop is to support the successful and convenient performance of the R and D by manufacture and maintenance of all sorts of laboratory equipment. (author). 9 tabs., 12 figs

Manufacture and maintenance of laboratory equipment

Energy Technology Data Exchange (ETDEWEB)

Kim, Jong Kyun; Hwang, Chang Kyu; Hwang, Bong Ha; Lee, Jong Wha; Yeom, Ki Eon; Park, Myung Ku; Hong, Soon Hyeon; Choi, Ho Young; An, Dae Kyu; An, Choon; Park, In Won; Kim, Kyeong Sik; Lee, In Bae; Yeom, Jeong Heon; Lee, Chul Ku; Sin, Keon Ju; Oh, Wan Ho; Choi, Byung Kwon; Chang, Kyeong Duk; Lee, Young Soon [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

1995-12-01

This report on the manufacture and maintenance of laboratory equipment contains working contents, scope and contents of a request working to the Machine Shop, also records the principal production design, manufacture contents and a relevant working drawing. The working content and scope of the Machine Shop is to support the successful and convenient performance of the Research and development by manufacture and maintenance of all sorts of laboratory equipment. 12 tabs., 5 figs. (Author) .new.

Service-Oriented Strategies for Manufacturing Firms

DEFF Research Database (Denmark)

Tan, Adrian; McAloone, Tim C.; Matzen, Detlef

2009-01-01

This chapter establishes PSS (Product/Service-Systems) approaches in the context of manufacturing firms and their existing product-oriented business. PSS can be seen as a strategy for manufacturing firms to gain competitive advantage in the market, but what market conditions and organisational......, customers and partners in business planning and strategy to reap the full benefits. Finally a path to how manufacturers can make the change from product to service-orientation is traced....

Research overview: Advanced Manufacturing in Switzerland

OpenAIRE

Schärer, Claudia

2016-01-01

SATW is convinced that industrial production methods will see fundamental changes over the coming years. Mastering new production technologies (advanced manufacturing) such as additive manufacturing and industry 4.0 will be vital to keep Swiss production at a competitive level. New additive manufacturing processes such as 3D printing offer revolutionary opportunities and have the potential to replace traditional production methods. Industry 4.0 has seen the definition of a new concept for...

Training for successful lean manufacturing implementation

OpenAIRE

Ichimura, Maki; Jahankhani, Hamid; Arunachalam, Subramaniam

2006-01-01

Implementing lean manufacturing is a complex and everlasting task. The workers involving in production processes are the pivot of the lean manufacturing implementation. Training is known as a vehicle to assist the implementation process. Despite awareness of the training importance, so far, a little is available to assist to organise an efficient training. This paper summarises the overview of lean manufacturing and discuss the importance of human resource within lean implementation process. ...

32 CFR 507.6 - Authority to manufacture.

Science.gov (United States)

2010-07-01

... 32 National Defense 3 2010-07-01 2010-07-01 true Authority to manufacture. 507.6 Section 507.6... PUBLIC RELATIONS MANUFACTURE AND SALE OF DECORATIONS, MEDALS, BADGES, INSIGNIA, COMMERCIAL USE OF HERALDIC DESIGNS AND HERALDIC QUALITY CONTROL PROGRAM Manufacture and Sale of Decorations, Medals, Badges...

Support given by the manufacturer

International Nuclear Information System (INIS)

Schomer, E.

1993-01-01

As regards German NPP, the purchaser has the control function and the manufacturer the role of a general planner binding together all supply lots. Therefore the manufacturer possesses a very broad and thorough detailed knowledge of the plant functioning and becomes a life-long important partner of the plant. Such partnership requires from the manufacturer to provide continuously available and economical services to the plant; he must work purposefully in a quality-conscious and innovative way. This is his vision, and he will comply with it over the whole service life of the plant. The importance of services is illustrated by a large number of examples. (orig./DG) [de

Integrated Glass Coating Manufacturing Line

Energy Technology Data Exchange (ETDEWEB)

Brophy, Brenor [Enki Technology Inc., San Jose, CA (United States)

2015-09-30

This project aims to enable US module manufacturers to coat glass with Enki’s state of the art tunable functionalized AR coatings at the lowest possible cost and highest possible performance by encapsulating Enki’s coating process in an integrated tool that facilitates effective process improvement through metrology and data analysis for greater quality and performance while reducing footprint, operating and capital costs. The Phase 1 objective was a fully designed manufacturing line, including fully specified equipment ready for issue of purchase requisitions; a detailed economic justification based on market prices at the end of Phase 1 and projected manufacturing costs and a detailed deployment plan for the equipment.

Cyber physical systems role in manufacturing technologies

Science.gov (United States)

Al-Ali, A. R.; Gupta, Ragini; Nabulsi, Ahmad Al

2018-04-01

Empowered by the recent development in single System-on-Chip, Internet of Things, and cloud computing technologies, cyber physical systems are evolving as a major controller during and post the manufacturing products process. In additional to their real physical space, cyber products nowadays have a virtual space. A product virtual space is a digital twin that is attached to it to enable manufacturers and their clients to better manufacture, monitor, maintain and operate it throughout its life time cycles, i.e. from the product manufacturing date, through operation and to the end of its lifespan. Each product is equipped with a tiny microcontroller that has a unique identification number, access code and WiFi conductivity to access it anytime and anywhere during its life cycle. This paper presents the cyber physical systems architecture and its role in manufacturing. Also, it highlights the role of Internet of Things and cloud computing in industrial manufacturing and factory automation.

#%Applications of artificial intelligence in intelligent manufacturing: a review

Institute of Scientific and Technical Information of China (English)

#

2017-01-01

#%Based on research into the applications of artificial intelligence (AI) technology in the manufacturing industry in recent years, we analyze the rapid development of core technologies in the new era of 'Internet plus AI', which is triggering a great change in the models, means, and ecosystems of the manufacturing industry, as well as in the development of AI. We then propose new models, means, and forms of intelligent manufacturing, intelligent manufacturing system architecture, and intelligent man-ufacturing technology system, based on the integration of AI technology with information communications, manufacturing, and related product technology. Moreover, from the perspectives of intelligent manufacturing application technology, industry, and application demonstration, the current development in intelligent manufacturing is discussed. Finally, suggestions for the appli-cation of AI in intelligent manufacturing in China are presented.

Research on TQCS Strategy of Digital Manufacturing Resource Management

Institute of Scientific and Technical Information of China (English)

ZHOU Zude; ZHANG Huifu

2006-01-01

Heterogeneous in nature, digitized manufacturing resources are geographically distributed, and owned by different organizations each having their own resource management policies and different access-and-cost models. In this paper, by means of stateful serviceData, we make manufacturing resources as grid nodes. Considering TQCS requirements of resources in the manufacturing industry, we capture the essentials of grid resource management models and propose the TQCS market model to inquire, browse and use manufacturing resources. The manufacturing resource integration will integrate and organize the manufacture technology resource to form the core manufacture powers.

Value networks in manufacturing sustainability and performance excellence

CERN Document Server

Uusitalo, Teuvo

2017-01-01

This book highlights innovative solutions together with various techniques and methods that can help support the manufacturing sector to excel in economic, social, and environmental terms in networked business environments. The book also furthers understanding of sustainable manufacturing from the perspective of value creation in manufacturing networks, by capitalizing on the outcomes of the European ‘Sustainable Value Creation in Manufacturing Networks’ project. New dynamics and uncertainties in modern markets call for innovative solutions in the global manufacturing sector. While the manufacturing sector is traditionally driven by technology, it also requires other managerial and organizational solutions in terms of network governance, business models, sustainable solution development for products and services, performance management portals, etc., which can provide major competitive advantages for companies. At the same time, the manufacturing industry is subject to a change process, where business net...

22 CFR 120.21 - Manufacturing license agreement.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Manufacturing license agreement. 120.21 Section... DEFINITIONS § 120.21 Manufacturing license agreement. An agreement (e.g., contract) whereby a U.S. person grants a foreign person an authorization to manufacture defense articles abroad and which involves or...

Two different techniques of manufacturing TMJ replacements - A technical report.

Science.gov (United States)

Kozakiewicz, Marcin; Wach, Tomasz; Szymor, Piotr; Zieliński, Rafał

2017-09-01

Presently, during the surgical treatment of the patients in maxillofacial surgery, one can use various medical implants. Moreover custom made implants are being used. Replacements may be fitted to the structure and shape of the human skull owing to CAD/CAM (custom aided design/manufacture) called customized implants. This study was aimed to report for the first time clinical material from which custom implants, using two different techniques, were manufactured to reconstruct the temporomandibular joint (TMJ). In this study, eleven patients with an average age of 54 years were included. All of the patients underwent TMJ reconstruction using direct metal laser sintering (DMLS) or computer numerical control milling (CNC) techniques for implant manufacture. Four of the eleven patients had a malignancy diagnosis, and seven had a benign diagnosis. Patients complained of hypomobility of the TMJ, facial asymmetry, pain and swelling of the preauricular region. Treatment included 7 CNC milled implants and 4 implants in DMLS. More metallic implant parts with a rough surface were associated with the DMLS technique. Post operational, uneventful healing was observed in all clinical cases during an average of 26.8 months of follow-up. Three months post-operation, facial nerve palsy, swallowing disturbances and pain were not observed. Infections, allergic reactions to materials and re-ankylosis were also not observed. Replacements received correct forms and functions owing to the CAM techniques. Post-operational maximal interincisal opening improved (p < 0.01) and was not significantly related to preoperational opening, age, sex, diagnosis or adjuvant radiotherapy. Considering both methods, the feature that differentiates the manufacture technique is the more subtractive surface finishing required for the DMLS implant than the CNC implant. Both techniques resulted the same clinical outcomes and can be used successfully in patients with neoplastic lesions and other TMJ disorders

Carbon-On-Carbon Manufacturing

Science.gov (United States)

Mungas, Gregory S. (Inventor); Buchanan, Larry (Inventor); Banzon, Jr., Jose T. (Inventor)

2017-01-01

The presently disclosed technology relates to carbon-on-carbon (C/C) manufacturing techniques and the resulting C/C products. One aspect of the manufacturing techniques disclosed herein utilizes two distinct curing operations that occur at different times and/or using different temperatures. The resulting C/C products are substantially non-porous, even though the curing operation(s) substantially gasify a liquid carbon-entrained filler material that saturates a carbon fabric that makes up the C/C products.

Developments in fuel manufacturing

International Nuclear Information System (INIS)

Ion, S.E.; Harrop, G.; Maricalva Gonzalez, J.

1995-01-01

The status of the investment and R and D programmes in the UK and Spanish fuel fabrication facilities is outlined. Due to a number of circumstances, BNFL and ENUSA have been in the forefront of capital investment, with associated commitment to engineering and scientific research and development. Carrying through this investment has allowed the embodiment of proven state of the art technologies in the design of fuel fabrication plants, with particular emphasis on meeting the future challenge of health and safety, and product quality, at an acceptable cost. ENUSA and BNFL currently supply fuel, not only to their respective 'home' markets but also to France, Belgium, Sweden, and Germany. Both organisations employ an International Business outlook and partake in focused and speculative R and D projects for the design and manufacture of nuclear fuel. (orig./HP)

Composite materials pipings: selection of basic materials and manufacturing process, quality control during manufacture

International Nuclear Information System (INIS)

Pays, M.F.

1997-01-01

The purpose of the paper is to present a summary of the knowledge acquired at the R and D on resins used as composite matrix, the resistance to hydrolysis and mechanical strength of pipings made from these materials, and on quality control during manufacture. The initial targets concerning the material selection, industrial manufacturing and quality control procedures are presented. The paper describes the results obtained concerning the investigation of the damage produced by hydrolysis in polyesters, vinyl esters and epoxides, the influence of temperature, reinforcement and the mechanical characterization of the tubing manufacturing. The performances of the nondestructive testings (radiography, ultrasonic controls, differential interferometry and infrared thermography) used are also reported. The paper ends with a further research and testings programme. (author)

Foundations & principles of distributed manufacturing elements of manufacturing networks, cyber-physical production systems and smart automation

CERN Document Server

Kühnle, Hermann

2015-01-01

The book presents a coherent description of distributed manufacturing, providing a solid base for further research on the subject as well as smart implementations in companies. It provides a guide for those researching and working in a range of fields, such as smart manufacturing, cloud computing, RFID tracking, distributed automation, cyber physical production and global design anywhere, manufacture anywhere solutions. Foundations & Principles of Distributed Manufacturing anticipates future advances in the fields of embedded systems, the Internet of Things and cyber physical systems, outlining how adopting these innovations could rapidly bring about improvements in key performance indicators, which could in turn generate competition pressure by rendering successful business models obsolete. In laying the groundwork for powerful theoretical models, high standards for the homogeneity and soundness of the suggested setups are applied. The book especially elaborates on the upcoming competition in online manu...

Open Manufacturing: Impacts of Resource Based View and Servitisation

DEFF Research Database (Denmark)

Yang, Cheng; Johansen, John

2010-01-01

The environment of manufacturing has faced significant changes in the past decade. Meanwhile, the traditional focus of manufacturing strategy is also impacted by resource-based view and servitisation. Thus, no matter from a practical or theoretical perspective, it is time to rethink what kind...... of view we can have on manufacturing. In this paper, the literature is reviewed firstly to track the evolution of theories on manufacturing strategy and to investigate new views on manufacturing from a theoretical perspective. This is followed by three case studies, which are used to explore how...... manufacturing is used from a practical perspective. The usages of manufacturing are classified into three groups and their relationships are discussed further. Based on these findings and inspired by open source software (OSS) and open innovation, a new paradigm on manufacturing termed as “open manufacturing...

21 CFR 1303.21 - Individual manufacturing quotas.

Science.gov (United States)

2010-04-01

... controlled substance listed in Schedule I or II, and who applies for a manufacturing quota, an individual... basic class. Any manufacturing quota fixed and issued by the Administrator shall be subject to his... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Individual manufacturing quotas. 1303.21 Section...

Towards Knowledge Management for Smart Manufacturing.

Science.gov (United States)

Feng, Shaw C; Bernstein, William Z; Hedberg, Thomas; Feeney, Allison Barnard

2017-09-01

The need for capturing knowledge in the digital form in design, process planning, production, and inspection has increasingly become an issue in manufacturing industries as the variety and complexity of product lifecycle applications increase. Both knowledge and data need to be well managed for quality assurance, lifecycle-impact assessment, and design improvement. Some technical barriers exist today that inhibit industry from fully utilizing design, planning, processing, and inspection knowledge. The primary barrier is a lack of a well-accepted mechanism that enables users to integrate data and knowledge. This paper prescribes knowledge management to address a lack of mechanisms for integrating, sharing, and updating domain-specific knowledge in smart manufacturing. Aspects of the knowledge constructs include conceptual design, detailed design, process planning, material property, production, and inspection. The main contribution of this paper is to provide a methodology on what knowledge manufacturing organizations access, update, and archive in the context of smart manufacturing. The case study in this paper provides some example knowledge objects to enable smart manufacturing.

CAD/CAM/AM applications in the manufacture of dental appliances.

Science.gov (United States)

Al Mortadi, Noor; Eggbeer, Dominic; Lewis, Jeffrey; Williams, Robert J

2012-11-01

The purposes of this study were to apply the latest developments in additive manufacturing (AM) construction and to evaluate the effectiveness of these computer-aided design and computer-aided manufacturing (CAD/CAM) techniques in the production of dental appliances. In addition, a new method of incorporating wire into a single build was developed. A scanner was used to capture 3-dimensional images of Class II Division 1 dental models that were translated onto a 2-dimensional computer screen. Andresen and sleep-apnea devices were designed in 3 dimensions by using FreeForm software (version 11; Geo Magics SensAble Group, Wilmington, Mass) and a phantom arm. The design was then exported and transferred to an AM machine for building. Copyright © 2012 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

Mining manufacturing data for discovery of high productivity process characteristics.

Science.gov (United States)

Charaniya, Salim; Le, Huong; Rangwala, Huzefa; Mills, Keri; Johnson, Kevin; Karypis, George; Hu, Wei-Shou

2010-06-01

Modern manufacturing facilities for bioproducts are highly automated with advanced process monitoring and data archiving systems. The time dynamics of hundreds of process parameters and outcome variables over a large number of production runs are archived in the data warehouse. This vast amount of data is a vital resource to comprehend the complex characteristics of bioprocesses and enhance production robustness. Cell culture process data from 108 'trains' comprising production as well as inoculum bioreactors from Genentech's manufacturing facility were investigated. Each run constitutes over one-hundred on-line and off-line temporal parameters. A kernel-based approach combined with a maximum margin-based support vector regression algorithm was used to integrate all the process parameters and develop predictive models for a key cell culture performance parameter. The model was also used to identify and rank process parameters according to their relevance in predicting process outcome. Evaluation of cell culture stage-specific models indicates that production performance can be reliably predicted days prior to harvest. Strong associations between several temporal parameters at various manufacturing stages and final process outcome were uncovered. This model-based data mining represents an important step forward in establishing a process data-driven knowledge discovery in bioprocesses. Implementation of this methodology on the manufacturing floor can facilitate a real-time decision making process and thereby improve the robustness of large scale bioprocesses. 2010 Elsevier B.V. All rights reserved.

Development of an ergonomics guideline for the furniture manufacturing industry.

Science.gov (United States)

Mirka, Gary A

2005-03-01

Industry-specific ergonomics guidelines are an important component in the four-pronged approach to workplace ergonomics currently pursued by the United States Occupational Safety and Health Administration. The American Furniture Manufacturers Association has taken the initiative of developing such a guideline for its members. The result of this effort is the "AFMA Voluntary Ergonomics Guideline for the Furniture Manufacturing Industry", a document that includes basic information about ergonomics program components as well as a compilation of work-proven, ergonomics best practices as submitted by members of the furniture manufacturing community. This guideline was developed through an industry-research-government partnership and made strategic use of the unique attributes that each sector brought to this effort. Outlined in this paper are some of the characteristics of this partnership including, the roles played by each, the different motivations for pursuing the guideline, the challenges faced during the development of the document, the successes experienced in this process, as well as a proposed outline for measuring the effectiveness of this effort. The hope is that this summary, and some of the lessons learned contained herein, would be helpful to others considering the prospect of developing such a guideline for their industry.

Emerging technologies in arthroplasty: additive manufacturing.

Science.gov (United States)

Banerjee, Samik; Kulesha, Gene; Kester, Mark; Mont, Michael A

2014-06-01

Additive manufacturing is an industrial technology whereby three-dimensional visual computer models are fabricated into physical components by selectively curing, depositing, or consolidating various materials in consecutive layers. Although initially developed for production of simulated models, the technology has undergone vast improvements and is currently increasingly being used for the production of end-use components in various aerospace, automotive, and biomedical specialties. The ability of this technology to be used for the manufacture of solid-mesh-foam monolithic and coated components of complex geometries previously considered unmanufacturable has attracted the attention of implant manufacturers, bioengineers, and orthopedic surgeons. Currently, there is a paucity of reports describing this fabrication method in the orthopedic literature. Therefore, we aimed to briefly describe this technology, some of the applications in other orthopedic subspecialties, its present use in hip and knee arthroplasty, and concerns with the present form of the technology. As there are few reports of clinical trials presently available, the true benefits of this technology can only be realized when studies evaluating the clinical and radiographic outcomes of cementless implants manufactured with additive manufacturing report durable fixation, less stress shielding, and better implant survivorship. Nevertheless, the authors believe that this technology holds great promise and may potentially change the conventional methods of casting, machining, and tooling for implant manufacturing in the future. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

16 CFR 700.2 - Date of manufacture.

Science.gov (United States)

2010-01-01

... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Date of manufacture. 700.2 Section 700.2... MAGNUSON-MOSS WARRANTY ACT INTERPRETATIONS OF MAGNUSON-MOSS WARRANTY ACT § 700.2 Date of manufacture... after July 4, 1975. When a consumer purchases repair of a consumer product the date of manufacture of...

Quality assurance in tube manufacture

International Nuclear Information System (INIS)

Depken, H.

1976-01-01

Reliability in service essential for many high-technology products fabricated today. This is particularly the case within the nuclear industry. Here defective materials or components may have diastrous consequences to the safety of human beings and the environment. A new concept - Quality Assurance - originates from this industry. The concept implies that all contractors, fabricators and material manufactures involved must prove that the quality control system used, fulfits particular requirements at all manufacturing, inspection and testing stages. These requirement are laid down in two standards issued by the U.S. Atomic Energy Commission and the American Society of Mechanical Engineers. These standards are discussed in the paper. As a manufacturer of steel products for nuclear applications Sandvik has been forced to establish a quality assurance system according to these principles. The Sandvik approach is briefly described with regard to organisation and other major quality assurance activities. Further the education and training of operators and technicians is touched upon. Finally some viewpoints regarding audits performed by customers of steel manufacturers are expressed. (author)

Hydrogen manufacturing using plasma reformers

Energy Technology Data Exchange (ETDEWEB)

Bromberg, L.; Cohn, D.R.; Rabinovich, A.; Hochgreb, S.; O`Brien, C. [Massachusetts Institute of Technology, Cambridge, MA (United States)

1996-10-01

Manufacturing of hydrogen from hydrocarbon fuels is needed for a variety of applications. These applications include fuel cells used in stationary electric power production and in vehicular propulsion. Hydrogen can also be used for various combustion engine systems. There is a wide range of requirements on the capacity of the hydrogen manufacturing system, the purity of the hydrogen fuel, and capability for rapid response. The overall objectives of a hydrogen manufacturing facility are to operate with high availability at the lowest possible cost and to have minimal adverse environmental impact. Plasma technology has potential to significantly alleviate shortcomings of conventional means of manufacturing hydrogen. These shortcomings include cost and deterioration of catalysts; limitations on hydrogen production from heavy hydrocarbons; limitations on rapid response; and size and weight requirements. In addition, use of plasma technology could provide for a greater variety of operating modes; in particular the possibility of virtual elimination of CO{sub 2} production by pyrolytic operation. This mode of hydrogen production may be of increasing importance due to recent additional evidence of global warming.

"Cut-and-paste" manufacture of multiparametric epidermal electronic systems

Science.gov (United States)

Lu, Nanshu; Yang, Shixuan; Wang, Pulin

2016-05-01

Epidermal electronics is a class of noninvasive and unobstructive skin-mounted, tattoo-like sensors and electronics capable of vital sign monitoring and establishing human-machine interface. The high cost of manpower, materials, vacuum equipment, and photolithographic facilities associated with its manufacture greatly hinders the widespread use of disposable epidermal electronics. Here we report a cost and time effective, completely dry, benchtop "cut-and-paste" method for the freeform and portable manufacture of multiparametric epidermal sensor systems (ESS) within minutes. This versatile method works for all types of thin metal and polymeric sheets and is compatible with any tattoo adhesives or medical tapes. The resulting ESS are multimaterial and multifunctional and have been demonstrated to noninvasively but accurately measure electrophysiological signals, skin temperature, skin hydration, as well as respiratory rate. In addition, planar stretchable coils exploiting double-stranded serpentine design have been successfully applied as wireless, passive epidermal strain sensors.

Manufacturing of NAA laboratory clean room

International Nuclear Information System (INIS)

Suwoto; Hasibuan, Djaruddin

2001-01-01

The ''NAA laboratory clean room'' has been built in the Reactor Serba Guna G.A. Siwabessy building. The erection of ''AAN laboratory clean room'' doing by started of preparation of the ''manufacturing procedure'' refer to ''Design and manufacturing neutron activation analysis clean room laboratory''. Manufacturing process and erection doing refer to procedures makes. By providing of the ''AAN laboratory clean room'' can be cocluded that the research activity and the user sevises in P2TRR well meet to be done

Challenges in Additive Manufacturing of Alumina

OpenAIRE

Gonzalez, Hugo

2016-01-01

Additive manufacturing is seen by many as the holy grail of manufacturing, the ability to produce parts nearly autonomously. Adding material rather than removing it would eliminate the need for expensive resources and machining. The recent expiration of key 3D printing patents has led to many advances in the field and has dramatically lowered the prices of 3D printers, making them accessible to the average individual. The one area where additive manufacturing is still in its infancy is in cer...

Chemistry, manufacturing and control (CMC) and clinical trial technical support for influenza vaccine manufacturers.

Science.gov (United States)

Wahid, Rahnuma; Holt, Renee; Hjorth, Richard; Berlanda Scorza, Francesco

2016-10-26

With the support of the Biomedical Advanced Research and Development Authority (BARDA) of the US Department of Health and Human Services, PATH has contributed to the World Health Organization's (WHO's) Global Action Plan for Influenza Vaccines (GAP) by providing technical and clinical assistance to several developing country vaccine manufacturers (DCVMs). GAP builds regionally based independent and sustainable influenza vaccine production capacity to mitigate the overall global shortage of influenza vaccines. The program also ensures adequate influenza vaccine manufacturing capacity in the event of an influenza pandemic. Since 2009, PATH has worked closely with two DCVMs in Vietnam: the Institute of Vaccines and Medical Biologicals (IVAC) and VABIOTECH. Beginning in 2013, PATH also began working with Torlak Institute in Serbia; Instituto Butantan in Brazil; Serum Institute of India Private Ltd. in India; and Changchun BCHT Biotechnology Co. (BCHT) in China. The DCVMs supported under the GAP program all had existing influenza vaccine manufacturing capability and required technical support from PATH to improve vaccine yield, process efficiency, and product formulation. PATH has provided customized technical support for the manufacturing process to each DCVM based on their respective requirements. Additionally, PATH, working with BARDA and WHO, supported several DCVMs in the clinical development of influenza vaccine candidates progressing toward national licensure or WHO prequalification. As a result of the activities outlined in this review, several companies were able to make excellent progress in developing state-of-the-art manufacturing processes and completing early phase clinical trials. Licensure trials are currently ongoing or planned for several DCVMs. Copyright © 2016 Elsevier Ltd. All rights reserved.

A Process Management System for Networked Manufacturing

Science.gov (United States)

Liu, Tingting; Wang, Huifen; Liu, Linyan

With the development of computer, communication and network, networked manufacturing has become one of the main manufacturing paradigms in the 21st century. Under the networked manufacturing environment, there exist a large number of cooperative tasks susceptible to alterations, conflicts caused by resources and problems of cost and quality. This increases the complexity of administration. Process management is a technology used to design, enact, control, and analyze networked manufacturing processes. It supports efficient execution, effective management, conflict resolution, cost containment and quality control. In this paper we propose an integrated process management system for networked manufacturing. Requirements of process management are analyzed and architecture of the system is presented. And a process model considering process cost and quality is developed. Finally a case study is provided to explain how the system runs efficiently.

Manufacture of Third-Generation Lentivirus for Preclinical Use, with Process Development Considerations for Translation to Good Manufacturing Practice.

Science.gov (United States)

Gándara, Carolina; Affleck, Valerie; Stoll, Elizabeth Ann

2018-02-01

Lentiviral vectors are used in laboratories around the world for in vivo and ex vivo delivery of gene therapies, and increasingly clinical investigation as well as preclinical applications. The third-generation lentiviral vector system has many advantages, including high packaging capacity, stable gene expression in both dividing and post-mitotic cells, and low immunogenicity in the recipient organism. Yet, the manufacture of these vectors is challenging, especially at high titers required for direct use in vivo, and further challenges are presented by the process of translating preclinical gene therapies toward manufacture of products for clinical investigation. The goals of this paper are to report the protocol for manufacturing high-titer third-generation lentivirus for preclinical testing and to provide detailed information on considerations for translating preclinical viral vector manufacture toward scaled-up platforms and processes in order to make gene therapies under Good Manufacturing Practice that are suitable for clinical trials.

LEAN Manufacturing

DEFF Research Database (Denmark)

Bilberg, Arne

. The mission with the strategy is to obtain competitive production in Denmark and in Western Europe based on the right combination of manufacturing principles, motivated and trained employees, level of automation, and cooperation with suppliers and customers worldwide. The strategy has resulted in technical...

Dynamic cellular manufacturing system design considering ...

Indian Academy of Sciences (India)

Kamal Deep

cellular manufacturing system in a company is division of ... designed to be assembled from a small number of stan- ..... contingency part process route in addition to the alternate .... istic industrial manufacturing vision considering multiple.

A system approach to controlling semiconductor manufacturing operations

OpenAIRE

Σταυράκης, Γιώργος Δ.

1987-01-01

Semicoductor manufacturers, faced with stiffening competition in both product cost and quality, require improved utilization of their development and manufacturing resources. Manufacturing philosophy must be changed, from focusing on short term results, to support continuous improvements in both output and quality. Such improvements demand better information management to monitor and control the manufacturing process. From these considerations, a process control methodology was develope...

Design for manufacturability with advanced lithography

CERN Document Server

Yu, Bei

2016-01-01

This book introduces readers to the most advanced research results on Design for Manufacturability (DFM) with multiple patterning lithography (MPL) and electron beam lithography (EBL).  The authors describe in detail a set of algorithms/methodologies to resolve issues in modern design for manufacturability problems with advanced lithography.  Unlike books that discuss DFM from the product level, or physical manufacturing level, this book describes DFM solutions from a circuit design level, such that most of the critical problems can be formulated and solved through combinatorial algorithms. Enables readers to tackle the challenge of layout decompositions for different patterning techniques; Presents a coherent framework, including standard cell compliance and detailed placement, to enable Triple Patterning Lithography (TPL) friendly design; Includes coverage of the design for manufacturability with E-Beam lithography.

Advances in 3D printing & additive manufacturing technologies

CERN Document Server

Pandey, Pulak; Kumar, L

2017-01-01

This edited volume comprises select chapters on advanced technologies for 3D printing and additive manufacturing and how these technologies have changed the face of direct, digital technologies for rapid production of models, prototypes and patterns. Because of its wide applications, 3D printing and additive manufacturing technology has become a powerful new industrial revolution in the field of manufacturing. The evolution of 3D printing and additive manufacturing technologies has changed design, engineering and manufacturing processes across industries such as consumer products, aerospace, medical devices and automotives. The objective of this book is to help designers, R&D personnel, and practicing engineers understand the state-of-the-art developments in the field of 3D Printing and Additive Manufacturing. .

21 CFR 610.50 - Date of manufacture.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Date of manufacture. 610.50 Section 610.50 Food... GENERAL BIOLOGICAL PRODUCTS STANDARDS Dating Period Limitations § 610.50 Date of manufacture. The date of manufacture shall be determined as follows: (a) For products for which an official standard of potency is...

Industry 4.0 implies lean manufacturing: research activities in industry 4.0 function as enablers for lean manufacturing

OpenAIRE

Sanders, Adam; Elangeswaran, Chola; Wulfsberg, Jens

2016-01-01

Purpose: Lean Manufacturing is widely regarded as a potential methodology to improve productivity and decrease costs in manufacturing organisations. The success of lean manufacturing demands consistent and conscious efforts from the organisation, and has to overcome several hindrances. Industry 4.0 makes a factory smart by applying advanced information and communication systems and future-oriented technologies. This paper analyses the incompletely perceived link between Industr...

Economics of Future Growth in Photovoltaics Manufacturing

Energy Technology Data Exchange (ETDEWEB)

Basore, Paul A.; Chung, Donald; Buonassisi, Tonio

2015-06-14

The past decade's record of growth in the photovoltaics manufacturing industry indicates that global investment in manufacturing capacity for photovoltaic modules tends to increase in proportion to the size of the industry. The slope of this proportionality determines how fast the industry will grow in the future. Two key parameters determine this slope. One is the annual global investment in manufacturing capacity normalized to the manufacturing capacity for the previous year (capacity-normalized capital investment rate, CapIR, units $/W). The other is how much capital investment is required for each watt of annual manufacturing capacity, normalized to the service life of the assets (capacity-normalized capital demand rate, CapDR, units $/W). If these two parameters remain unchanged from the values they have held for the past few years, global manufacturing capacity will peak in the next few years and then decline. However, it only takes a small improvement in CapIR to ensure future growth in photovoltaics. Any accompanying improvement in CapDR will accelerate that growth.

Resistance welding equipment manufacturing capability for exports

Energy Technology Data Exchange (ETDEWEB)

Sastry, V.S.; Raju, Y.S.; Somani, A.K.; Setty, D.S.; Rameswara Raw, A.; Hermantha Rao, G.V.S.; Jayaraj, R.N. [Nuclear Fuel Complex, Dept. of Atomic Energy, Hyderbad (India)

2010-07-01

Indian Pressurised Heavy Water Reactor (PHWR) fuel bundle is fully welded and is unique in its design. Appendage welding, end closure welding, and end plate welding is carried out using resistance welding technique. Out of many joining processes available, resistance-welding process is reliable, environment friendly and best suitable for mass production applications. Nuclear Fuel Complex (NFC), an industrial unit is established in Hyderabad, under the aegis of the Dept of Atomic Energy to manufacture fuel for Pressurised Heavy Water Reactors. From inception, NFC has given importance for self-reliance and indigenization with respect to manufacturing process and equipment. Sintering furnaces, centreless grinders, appendage-welding machines, end-closure welding equipment and end-plate welding equipments, which were initially imported, are either indigenized or designed and manufactured in house. NFC has designed, manufactured a new appendage-welding machine for manufacturing 37 element fuel bundles. Recently NFC has bagged an order from IAEA through international bidding for design, manufacture, supply, erection and commissioning of end-closure welding equipment. The paper gives in detail the salient features of these welding equipment. (author)

Advanced Material Strategies for Next-Generation Additive Manufacturing.

Science.gov (United States)

Chang, Jinke; He, Jiankang; Mao, Mao; Zhou, Wenxing; Lei, Qi; Li, Xiao; Li, Dichen; Chua, Chee-Kai; Zhao, Xin

2018-01-22

Additive manufacturing (AM) has drawn tremendous attention in various fields. In recent years, great efforts have been made to develop novel additive manufacturing processes such as micro-/nano-scale 3D printing, bioprinting, and 4D printing for the fabrication of complex 3D structures with high resolution, living components, and multimaterials. The development of advanced functional materials is important for the implementation of these novel additive manufacturing processes. Here, a state-of-the-art review on advanced material strategies for novel additive manufacturing processes is provided, mainly including conductive materials, biomaterials, and smart materials. The advantages, limitations, and future perspectives of these materials for additive manufacturing are discussed. It is believed that the innovations of material strategies in parallel with the evolution of additive manufacturing processes will provide numerous possibilities for the fabrication of complex smart constructs with multiple functions, which will significantly widen the application fields of next-generation additive manufacturing.

Advanced Material Strategies for Next-Generation Additive Manufacturing

Directory of Open Access Journals (Sweden)

Jinke Chang

2018-01-01

Full Text Available Additive manufacturing (AM has drawn tremendous attention in various fields. In recent years, great efforts have been made to develop novel additive manufacturing processes such as micro-/nano-scale 3D printing, bioprinting, and 4D printing for the fabrication of complex 3D structures with high resolution, living components, and multimaterials. The development of advanced functional materials is important for the implementation of these novel additive manufacturing processes. Here, a state-of-the-art review on advanced material strategies for novel additive manufacturing processes is provided, mainly including conductive materials, biomaterials, and smart materials. The advantages, limitations, and future perspectives of these materials for additive manufacturing are discussed. It is believed that the innovations of material strategies in parallel with the evolution of additive manufacturing processes will provide numerous possibilities for the fabrication of complex smart constructs with multiple functions, which will significantly widen the application fields of next-generation additive manufacturing.

Advanced Material Strategies for Next-Generation Additive Manufacturing

Science.gov (United States)

Chang, Jinke; He, Jiankang; Zhou, Wenxing; Lei, Qi; Li, Xiao; Li, Dichen

2018-01-01

Additive manufacturing (AM) has drawn tremendous attention in various fields. In recent years, great efforts have been made to develop novel additive manufacturing processes such as micro-/nano-scale 3D printing, bioprinting, and 4D printing for the fabrication of complex 3D structures with high resolution, living components, and multimaterials. The development of advanced functional materials is important for the implementation of these novel additive manufacturing processes. Here, a state-of-the-art review on advanced material strategies for novel additive manufacturing processes is provided, mainly including conductive materials, biomaterials, and smart materials. The advantages, limitations, and future perspectives of these materials for additive manufacturing are discussed. It is believed that the innovations of material strategies in parallel with the evolution of additive manufacturing processes will provide numerous possibilities for the fabrication of complex smart constructs with multiple functions, which will significantly widen the application fields of next-generation additive manufacturing. PMID:29361754

PREFACE: Trends in Aerospace Manufacturing 2009 International Conference

Science.gov (United States)

Ridgway, Keith; Gault, Rosemary; Allen, Adrian

2011-12-01

The aerospace industry is rapidly changing. New aircraft structures are being developed and aero-engines are becoming lighter and more environmentally friendly. In both areas, innovative materials and manufacturing methods are used in an attempt to get maximum performance for minimum cost. At the same time, the structure of the industry has changed and there has been a move from large companies designing, manufacturing components and assembling aircraft to one of large global supply chains headed by large system integrators. All these changes have forced engineers and managers to bring in innovations in design, materials, manufacturing technologies and supply chain management. In September 2009, the Advanced Manufacturing Research Centre (AMRC) at the University of Sheffield held the inaugural Trends in Aerospace Manufacturing conference (TRAM09). This brought together 28 speakers over two days, who presented in sessions on advanced manufacturing trends for the aerospace sector. Areas covered included new materials, including composites, advanced machining, state of the art additive manufacturing techniques, assembly and supply chain issues.

Design and manufacture of high performance hollow engine valves by Additive Layer Manufacturing

International Nuclear Information System (INIS)

Cooper, D.; Thornby, J.; Blundell, N.; Henrys, R.; Williams, M.A.; Gibbons, G.

2015-01-01

Highlights: • High performance engine valve has been redesigned and optimised for and using ALM. • FEA was utilised to optimise and select a design for manufacture and testing. • Micro computed tomography was used in design and validation as an NDT technique. • Real world test of components was conducted to evaluate their performance. • Has demonstrated the potential for ALM in a high performance engineering context. - Abstract: Additive Layer Manufacture (ALM) of metallic components provides significant opportunities for the reduction of component weight, in order to realise improvements in vehicle fuel efficiency or performance. This paper examines the potential benefits of ALM with regard to reducing the weight of Internal Combustion Engine inlet or exhaust valves. A case study component is presented, for which an improved ALM design has been created, manufactured and evaluated. Micro-Computed Tomography (μ-CT) scanning was utilised to reverse engineer an original component, and to assess the ALM component’s internal geometry and material integrity. The case study valve was re-designed using Finite Element Analysis (FEA) to select a light weighted design which provides a conservative 9.4 g, (20%) weight saving on the Original Equipment Manufacturer (OEM) component. An engine test of over 175,000 cycles at between 2000 and 9500 rpm was conducted, after which μ-CT scanning confirmed no evidence of internal cracking, failure or significant deformation

Mortality of workers employed in shoe manufacturing: an update.

Science.gov (United States)

Lehman, Everett J; Hein, Misty J

2006-07-01

In the late 1970s, the National Institute for Occupational Safety and Health identified two shoe manufacturing facilities where workers experienced relatively "pure" exposures to toluene. A mortality study was conducted through December 31, 1982. An original study did not detect elevated leukemia mortality but did detect increased lung cancer mortality. The present study is an update of the mortality of the original cohort. The study cohort consisted of workers employed 1 month or more between 1940 and 1979 at two Ohio shoe manufacturing plants. Vital status was ascertained through December 31, 1999. Seven thousand eight hundred twenty eight workers, contributing 300,777 person years, were available for analysis. An excess of lung cancer deaths persisted with additional years of follow-up (SMR = 1.36, 95% confidence interval (CI) = 1.19-1.54). Trend tests did not indicate a positive trend between lung cancer risk and duration of employment. Mortality from leukemia was not significantly elevated in the updated analysis. Results indicate a possible association between lung cancer mortality and exposure to chronic, low-levels of organic solvents. Although the strength of this conclusion was weakened by the lack of increasing lung cancer risk in relation to duration of employment, other studies have supported this association. Published 2006 Wiley-Liss, Inc.

The Clean Energy Manufacturing Analysis Center (CEMAC): Providing Analysis and Insights on Clean Technology Manufacturing

Energy Technology Data Exchange (ETDEWEB)

Johnson, Nicholi S [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

2017-09-28

The U.S. Department of Energy's Clean Energy Manufacturing Analysis Center (CEMAC) provides objective analysis and up-to-date data on global supply chains and manufacturing of clean energy technologies. Policymakers and industry leaders seek CEMAC insights to inform choices to promote economic growth and the transition to a clean energy economy.

A risk-based auditing process for pharmaceutical manufacturers.

Science.gov (United States)

Vargo, Susan; Dana, Bob; Rangavajhula, Vijaya; Rönninger, Stephan

2014-01-01

The purpose of this article is to share ideas on developing a risk-based model for the scheduling of audits (both internal and external). Audits are a key element of a manufacturer's quality system and provide an independent means of evaluating the manufacturer's or the supplier/vendor's compliance status. Suggestions for risk-based scheduling approaches are discussed in the article. Pharmaceutical manufacturers are required to establish and implement a quality system. The quality system is an organizational structure defining responsibilities, procedures, processes, and resources that the manufacturer has established to ensure quality throughout the manufacturing process. Audits are a component of the manufacturer's quality system and provide a systematic and an independent means of evaluating the manufacturer's overall quality system and compliance status. Audits are performed at defined intervals for a specified duration. The intention of the audit process is to focus on key areas within the quality system and may not cover all relevant areas during each audit. In this article, the authors provide suggestions for risk-based scheduling approaches to aid pharmaceutical manufacturers in identifying the key focus areas for an audit.

Additive manufacturing in production: challenges and opportunities

Science.gov (United States)

Ahuja, Bhrigu; Karg, Michael; Schmidt, Michael

2015-03-01

Additive manufacturing, characterized by its inherent layer by layer fabrication methodology has been coined by many as the latest revolution in the manufacturing industry. Due to its diversification of Materials, processes, system technology and applications, Additive Manufacturing has been synonymized with terminology such as Rapid prototyping, 3D printing, free-form fabrication, Additive Layer Manufacturing, etc. A huge media and public interest in the technology has led to an innovative attempt of exploring the technology for applications beyond the scope of the traditional engineering industry. Nevertheless, it is believed that a critical factor for the long-term success of Additive Manufacturing would be its ability to fulfill the requirements defined by the traditional manufacturing industry. A parallel development in market trends and product requirements has also lead to a wider scope of opportunities for Additive Manufacturing. The presented paper discusses some of the key challenges which are critical to ensure that Additive Manufacturing is truly accepted as a mainstream production technology in the industry. These challenges would highlight on various aspects of production such as product requirements, process management, data management, intellectual property, work flow management, quality assurance, resource planning, etc. In Addition, changing market trends such as product life cycle, mass customization, sustainability, environmental impact and localized production will form the foundation for the follow up discussion on the current limitations and the corresponding research opportunities. A discussion on ongoing research to address these challenges would include topics like process monitoring, design complexity, process standardization, multi-material and hybrid fabrication, new material development, etc.

Effusion plate using additive manufacturing methods

Science.gov (United States)

Johnson, Thomas Edward; Keener, Christopher Paul; Ostebee, Heath Michael; Wegerif, Daniel Gerritt

2016-04-12

Additive manufacturing techniques may be utilized to construct effusion plates. Such additive manufacturing techniques may include defining a configuration for an effusion plate having one or more internal cooling channels. The manufacturing techniques may further include depositing a powder into a chamber, applying an energy source to the deposited powder, and consolidating the powder into a cross-sectional shape corresponding to the defined configuration. Such methods may be implemented to construct an effusion plate having one or more channels with a curved cross-sectional geometry.

PERSPECTIVES FOR FOG COMPUTING IN MANUFACTURING

Directory of Open Access Journals (Sweden)

Jakub PIZOŃ

2016-09-01

Full Text Available This article discusses ongoing efforts to enable the fog computing vision in manufacturing. As a new paradigm of computing implementation of fog computing faces many challenges that open perspective of new applications within a field of manufacturing. It is expected that fog computing will be one of factors that will accelerate development of in forth industrial revolution. In this article we discuss the perspectives of manufacturing companies surrounded by new solutions of CPS, CPPS and CM in relation to fog computing.

Plant Evolution: A Manufacturing Network Perspective

DEFF Research Database (Denmark)

Yang, Cheng; Johansen, John; Boer, Harry

2009-01-01

Viewing them as portfolios of products and processes, we aim to address how plants evolve in the context of a manufacturing network and how the evolution of one plant impacts other plants in the same manufacturing network. Based on discussions of ten plants from three Danish companies, we identify...... two different trajectories. Together, these trajectories determine the evolution of a manufacturing network. Factors appearing to affect the two trajectories include competencies built up, transferred or acquired locally, market potential, performance considerations, local, situational factors...

3D Ceramic Microfluidic Device Manufacturing

International Nuclear Information System (INIS)

Natarajan, Govindarajan; Humenik, James N

2006-01-01

Today, semiconductor processing serves as the backbone for the bulk of micromachined devices. Precision lithography and etching technology used in the semiconductor industry are also leveraged by alternate techniques like electroforming and molding. The nature of such processing is complex, limited and expensive for any manufacturing foundry. This paper details the technology elements developed to manufacture cost effective and versatile microfluidic devices for applications ranging from medical diagnostics to characterization of bioassays. Two applications using multilayer ceramic technology to manufacture complex 3D microfluidic devices are discussed

Leukaemia incidence among workers in the shoe and boot manufacturing industry: a case-control study

Directory of Open Access Journals (Sweden)

Forand Steven P

2004-08-01

Full Text Available Abstract Background Previous reports have indicated an excess of leukaemia in Broome County, New York, particularly in the Town of Union. Surveillance of cancer incidence data indicates that a large proportion of these cases occurred among males ages 65 and older. Shoe and boot manufacturing has been the largest single industry in this area throughout much of the past century. Occupational studies from Europe suggest a link between leukaemia and employment in the shoe and boot manufacturing industry. However, researchers have not found a positive association between leukaemia and employment in the shoe industry among workers in the United States. Methods A matched case-control study was conducted to investigate the association between leukaemia incidence among males 65 and older and employment in the shoe and boot manufacturing industry. Thirty-six cases of leukaemia occurring between 1981–1990; among males age 65 and older; residing in the town of Union met the study case criteria. Death certificates were obtained for each of the cases. These were matched to death certificates of 144 controls on date of death and date of birth +/- 1 year. Death certificates were then examined to determine the employer and occupation of each study subject. Conditional logistic regression was used to determine the risk of leukaemia among those working in the industry. Results The risk of both leukaemia (OR = 1.47; 95% CI 0.70, 3.09 and acute myeloid leukaemia (OR = 1.19; 95% CI 0.33, 4.28 were elevated among those employed in the shoe and boot manufacturing industry, however neither was statistically significant. Conclusion The results, though suggestive of an association between leukaemia and employment in the shoe and boot manufacturing industry, were not statistically conclusive due mainly to limited study power. Several additional limitations may also have prevented the observance of more conclusive findings. Better exposure assessment, information on

Additive Manufacturing of Aerospace Propulsion Components

Science.gov (United States)

Misra, Ajay K.; Grady, Joseph E.; Carter, Robert

2015-01-01

The presentation will provide an overview of ongoing activities on additive manufacturing of aerospace propulsion components, which included rocket propulsion and gas turbine engines. Future opportunities on additive manufacturing of hybrid electric propulsion components will be discussed.

Assessment of local wood species used for the manufacture of cookware and the perception of chemical benefits and chemical hazards associated with their use in Kumasi, Ghana

Directory of Open Access Journals (Sweden)

Mensah John Kenneth

2012-12-01

Full Text Available Abstract Background Historical proven wood species have no reported adverse health effect associated with its past use. Different historical proven species have traditionally been used to manufacture different wooden food contact items. This study uses survey questionnaires to assess suppliers’, manufacturers’, retailers’ and consumers’ (end-users’ preferences for specific wood species, to examine the considerations that inform these preferences and to investigate the extent of awareness of the chemical benefits and chemical hazards associated with wooden food contact material use. Methods Through the combined use of a cross sectional approach and a case study design, 25 suppliers, 25 manufacturers, 25 retailers and 125 consumers (end-users of wooden food contact materials in four suburbs in Kumasi Metropolitan Area (Anloga junction, Ahinsan Bus Stop, Ahwia-Pankrono and Race Course and Ashanti Akyim Agogo in the Ashanti Akyim North District of the Ashanti Region were administered with closed ended questionnaires. The questionnaires were prepared in English, but local language, Twi, was used to translate and communicate the content of the questionnaire where necessary. Results Suppliers’, manufacturers’ and retailers’ preferences for specific wood species for most wooden cookware differed from that of consumers (end-users. But all respondent groups failed to indicate any awareness of chemical benefits or chemical hazards associated with either the choice of specific wood species for specific wooden cookware or with the general use of wooden food contact materials. The lack of appreciation of chemical benefits or hazards associated with active principles of wooden cookware led to heavy reliance of consumers (end-users on the wood density, price, attractive grain pattern and colour or on the judgement of retailers in their choice of specific species for a wooden cookware. Conclusion This study contributes some practical suggestions

Development of the supply chain oriented quality assurance system for aerospace manufacturing SMEs and its implementation perspectives

Science.gov (United States)

Hussein, Abdullahi; Cheng, Kai

2016-10-01

Aerospace manufacturing SMEs are continuously facing the challenge on managing their supply chain and complying with the aerospace manufacturing quality standard requirement due to their lack of resources and the nature of business. In this paper, the ERP system based approach is presented to quality control and assurance work in light of seamless integration of in-process production data and information internally and therefore managing suppliers more effectively and efficiently. The Aerospace Manufacturing Quality Assurance Standard (BS/EN9100) is one of the most recognised and essential protocols for developing the industry-operated-and-driven quality assurance systems. The research investigates using the ERP based system as an enabler to implement BS/EN9100 quality management system at manufacturing SMEs and the associated implementation and application perspectives. An application case study on a manufacturing SME is presented by using the SAP based implementation, which helps further evaluate and validate the approach and application system development.

Additive manufacturing for consumer-centric business models

DEFF Research Database (Denmark)

Bogers, Marcel; Hadar, Ronen; Bilberg, Arne

2016-01-01

Digital fabrication—including additive manufacturing (AM), rapid prototyping and 3D printing—has the potential to revolutionize the way in which products are produced and delivered to the customer. Therefore, it challenges companies to reinvent their business model—describing the logic of creating...... and capturing value. In this paper, we explore the implications that AM technologies have for manufacturing systems in the new business models that they enable. In particular, we consider how a consumer goods manufacturer can organize the operations of a more open business model when moving from a manufacturer......-centric to a consumer-centric value logic. A major shift includes a move from centralized to decentralized supply chains, where consumer goods manufacturers can implement a “hybrid” approach with a focus on localization and accessibility or develop a fully personalized model where the consumer effectively takes over...

Fundamentals of semiconductor manufacturing and process control

CERN Document Server

May, Gary S

2006-01-01

A practical guide to semiconductor manufacturing from process control to yield modeling and experimental design Fundamentals of Semiconductor Manufacturing and Process Control covers all issues involved in manufacturing microelectronic devices and circuits, including fabrication sequences, process control, experimental design, process modeling, yield modeling, and CIM/CAM systems. Readers are introduced to both the theory and practice of all basic manufacturing concepts. Following an overview of manufacturing and technology, the text explores process monitoring methods, including those that focus on product wafers and those that focus on the equipment used to produce wafers. Next, the text sets forth some fundamentals of statistics and yield modeling, which set the foundation for a detailed discussion of how statistical process control is used to analyze quality and improve yields. The discussion of statistical experimental design offers readers a powerful approach for systematically varying controllable p...

The Economics of Big Area Addtiive Manufacturing

Energy Technology Data Exchange (ETDEWEB)

Post, Brian [Oak Ridge National Laboratory (ORNL); Lloyd, Peter D [ORNL; Lindahl, John [Oak Ridge National Laboratory (ORNL); Lind, Randall F [ORNL; Love, Lonnie J [ORNL; Kunc, Vlastimil [ORNL

2016-01-01

Case studies on the economics of Additive Manufacturing (AM) suggest that processing time is the dominant cost in manufacturing. Most additive processes have similar performance metrics: small part sizes, low production rates and expensive feedstocks. Big Area Additive Manufacturing is based on transitioning polymer extrusion technology from a wire to a pellet feedstock. Utilizing pellets significantly increases deposition speed and lowers material cost by utilizing low cost injection molding feedstock. The use of carbon fiber reinforced polymers eliminates the need for a heated chamber, significantly reducing machine power requirements and size constraints. We hypothesize that the increase in productivity coupled with decrease in feedstock and energy costs will enable AM to become more competitive with conventional manufacturing processes for many applications. As a test case, we compare the cost of using traditional fused deposition modeling (FDM) with BAAM for additively manufacturing composite tooling.

Sustainable manufacturing challenges, solutions and implementation perspectives

CERN Document Server

Seliger, Günther; Bonvoisin, Jérémy

2017-01-01

Sustainability imposes an unprecedented challenge on society and has become the driving force of an urgent search for innovative solutions in all branches of economy. Manufacturing plays a key role in many areas of human living, and it is both part of the problem and of the solution. This book offers an overview of the broad field of research on sustainability in manufacturing with a particular focus on manufacturing technology and management. It summarizes the current challenges, describes best in class methods for development of sustainable manufacturing solutions and offers implementation perspectives. This volume covers areas of research such as production processes, product development, business model and corporate development, macro economy and education. The target audience primarily comprises research experts and practitioners in the field of manufacturing, but the book may also be beneficial for graduate students. .

Single-use disposable technologies for biopharmaceutical manufacturing.

Science.gov (United States)

Shukla, Abhinav A; Gottschalk, Uwe

2013-03-01

The manufacture of protein biopharmaceuticals is conducted under current good manufacturing practice (cGMP) and involves multiple unit operations for upstream production and downstream purification. Until recently, production facilities relied on the use of relatively inflexible, hard-piped equipment including large stainless steel bioreactors and tanks to hold product intermediates and buffers. However, there is an increasing trend towards the adoption of single-use technologies across the manufacturing process. Technical advances have now made an end-to-end single-use manufacturing facility possible, but several aspects of single-use technology require further improvement and are continually evolving. This article provides a perspective on the current state-of-the-art in single-use technologies and highlights trends that will improve performance and increase the market penetration of disposable manufacturing in the future. Copyright © 2012 Elsevier Ltd. All rights reserved.

Advanced Manufacturing Laboratory

Data.gov (United States)

Federal Laboratory Consortium — The Advanced Manufacturing Laboratory at the University of Maryland provides the state of the art facilities for realizing next generation products and educating the...

Low Cost Lithography Tool for High Brightness LED Manufacturing

Energy Technology Data Exchange (ETDEWEB)

Andrew Hawryluk; Emily True

2012-06-30

The objective of this activity was to address the need for improved manufacturing tools for LEDs. Improvements include lower cost (both capital equipment cost reductions and cost-ofownership reductions), better automation and better yields. To meet the DOE objective of $1- 2/kilolumen, it will be necessary to develop these highly automated manufacturing tools. Lithography is used extensively in the fabrication of high-brightness LEDs, but the tools used to date are not scalable to high-volume manufacturing. This activity addressed the LED lithography process. During R&D and low volume manufacturing, most LED companies use contact-printers. However, several industries have shown that these printers are incompatible with high volume manufacturing and the LED industry needs to evolve to projection steppers. The need for projection lithography tools for LED manufacturing is identified in the Solid State Lighting Manufacturing Roadmap Draft, June 2009. The Roadmap states that Projection tools are needed by 2011. This work will modify a stepper, originally designed for semiconductor manufacturing, for use in LED manufacturing. This work addresses improvements to yield, material handling, automation and throughput for LED manufacturing while reducing the capital equipment cost.

Recent development of cellular manufacturing systems

Indian Academy of Sciences (India)

be manufactured in a cell, and the machines, which will comprise that cell, can be ... approaches for the CF problem which is referred to as Production Flow Analysis (PFA). ... programming model of cellular manufacturing system design which ...

THE DYNAMICS OF BEST MANUFACTURING PRACTICES

DEFF Research Database (Denmark)

Timenes Laugen, Bjørge; Acur, Nuran; Boer, Harry

and manufacturing, and improving manufacturing process maintain their status as best practices, while servitization and supply chain management are new best practices. Globalization and responsibility are proposed as promising practices, and technology is suggested as a qualifying practice....

Associations of polychlorinated biphenyl exposure and endogenous hormones with diabetes in post-menopausal women previously employed at a capacitor manufacturing plant.

Science.gov (United States)

Persky, Victoria; Piorkowski, Julie; Turyk, Mary; Freels, Sally; Chatterton, Robert; Dimos, John; Bradlow, H Leon; Chary, Lin Kaatz; Burse, Virlyn; Unterman, Terry; Sepkovic, Daniel; McCann, Kenneth

2011-08-01

There is an increasing body of literature showing associations of organochlorine exposure with risk of diabetes and insulin resistance. Some studies suggest that associations differ by gender and that diabetes risk, in turn, may be affected by endogenous steroid hormones. This report examines the relationships of serum PCBs and endogenous hormones with history of diabetes in a cohort of persons previously employed at a capacitor manufacturing plant. A total of 118 women were post-menopausal with complete data, of whom 93 were not using steroid hormones in 1996, at the time of examination, which included a survey of exposure and medical history, height, weight and collection of blood and urine for measurements of lipids, liver function, hematologic markers and endogenous hormones. This analysis examines relationships of serum polychlorinated biphenyls (PCBs), work exposure and endogenous hormones with self-reported history of diabetes after control for potential confounders. All PCB exposure groups were significantly related to history of diabetes, but not to insulin resistance as measured by the homeostatic model assessment of insulin resistance (HOMA-IR) in non-diabetics. Diabetes was also independently and inversely associated with follicle stimulating hormone (FSH), dehydroepiandrosterone sulfate (DHEAS) and triiodothyronine (T3) uptake. HOMA-IR was positively associated with body mass index (BMI) and C-reactive protein (CRP) and inversely associated with sex hormone binding globulin (SHBG) and T3 uptake after control for PCB exposure. Possible biologic mechanisms are discussed. This study confirms previous reports relating PCB exposure to diabetes and suggests possible hormonal pathways deserving further exploration. Copyright © 2011 Elsevier Inc. All rights reserved.

Manufacture of Damascus steel: Metallographic study

International Nuclear Information System (INIS)

Criado, A.J.; Martinez, J.A.; Calabres, R.; Arias, D.

1997-01-01

Damascus Steel is the denomination that the Europeans gave to the material with which the musulman swords were manufactured during the Era of the Crusades. This hypereutectoid steel presents a high content in carbon more than 0.8%, and in some cases up to 2% in weight. The secret of its good mechanical characteristics is based in the hot forging process in the temperatures interval between 650 and 850 degree centigree. The final quenching in water brine or other aqueous solutions, confers to the swords manufactured with this steel a good resistance to its cutting edge and a high toughness. In the present investigation, the manufacture processes of this type of steel are studied. Electronic scanning microscopy has been applied to the study of materials manufactured by the authors following the ancient craftsmen methods of forging and quenching. (Author) 16 refs

Low-cost solar module manufacturing

International Nuclear Information System (INIS)

Little, Roger G.; Nowlan, Michael J.; Matthei, Keith W.; Darkazalli, Ghazi

1997-01-01

As the market for terrestrial photovoltaic modules expands beyond the 80 MW per year level, module manufacturers are adopting a number of cost-reduction strategies, including the use of higher throughput equipment, increased process automation, and the fabrication of larger area cells and modules. This paper reviews recent activities at Spire Corporation in the development of advanced module manufacturing and testing equipment

Research of Manufacture Time Management System Based on PLM

Science.gov (United States)

Jing, Ni; Juan, Zhu; Liangwei, Zhong

This system is targeted by enterprises manufacturing machine shop, analyzes their business needs and builds the plant management information system of Manufacture time and Manufacture time information management. for manufacturing process Combined with WEB technology, based on EXCEL VBA development of methods, constructs a hybrid model based on PLM workshop Manufacture time management information system framework, discusses the functionality of the system architecture, database structure.

Metrology for Fuel Cell Manufacturing

Energy Technology Data Exchange (ETDEWEB)

Stocker, Michael [National Inst. of Standards and Technology, Gaithersburg, MD (United States); Stanfield, Eric [National Inst. of Standards and Technology, Gaithersburg, MD (United States)

2015-02-04

The project was divided into three subprojects. The first subproject is Fuel Cell Manufacturing Variability and Its Impact on Performance. The objective was to determine if flow field channel dimensional variability has an impact on fuel cell performance. The second subproject is Non-contact Sensor Evaluation for Bipolar Plate Manufacturing Process Control and Smart Assembly of Fuel Cell Stacks. The objective was to enable cost reduction in the manufacture of fuel cell plates by providing a rapid non-contact measurement system for in-line process control. The third subproject is Optical Scatterfield Metrology for Online Catalyst Coating Inspection of PEM Soft Goods. The objective was to evaluate the suitability of Optical Scatterfield Microscopy as a viable measurement tool for in situ process control of catalyst coatings.

WWER-1000 nuclear fuel manufacturing process at PJSC MSZ

International Nuclear Information System (INIS)

Morylev, A.; Bagdatyeva, E.; Aksenov, P.

2015-01-01

In this report a brief description of WWER-1000 fuel manufacturing process steps at PJSC MSZ as: uranium dioxide powder fabrication; fuel pellet manufacture fuel rod manufacture working assembly and fuel assembly manufacture is given. The implemented innovations are also presented

Initiatives to Improve Quality of Additively Manufactured Parts

Science.gov (United States)

Waller, Jess; Nichols, Charles

2017-01-01

NASA is providing leadership in an international effort linking government and industry resources to speed adoption of additive manufactured (AM) parts. Participants include government agencies (NASA, USAF, NIST, FAA), industry (commercial aerospace, NDE manufacturers, AM equipment manufacturers), standards organizations and academia. NASA is also partnering with its international space exploration organizations such as ESA and JAXA. NDT is identified as a universal need for all aspects of additive manufacturing.

Redesigning Manufacturing Footprint from Dynamic Perspective

DEFF Research Database (Denmark)

Yang, Cheng; Farooq, Sami; Johansen, John

2009-01-01

footprint to address the constantly emerging new challenges by giving a holistic approach from dynamic perspective. Three Danish companies are presented. The way they developed their international manufacturing networks is analysed historically, and their redesigning of manufacturing footprint is expressed...... as how to re-assign portfolios of products and processes between specific plants within the same manufacturing network at one point in time. The strategic factors that have impact on such decisions are discussed and classified into two groups. Last, a holistic framework and a process model is presented...

Additive manufacture (3d printing) of plasma diagnostic components and assemblies for fusion experiments

Science.gov (United States)

Sieck, Paul; Woodruff, Simon; Stuber, James; Romero-Talamas, Carlos; Rivera, William; You, Setthivoine; Card, Alexander

2015-11-01

Additive manufacturing (or 3D printing) is now becoming sufficiently accurate with a large range of materials for use in printing sensors needed universally in fusion energy research. Decreasing production cost and significantly lowering design time of energy subsystems would realize significant cost reduction for standard diagnostics commonly obtained through research grants. There is now a well-established set of plasma diagnostics, but these expensive since they are often highly complex and require customization, sometimes pace the project. Additive manufacturing (3D printing) is developing rapidly, including open source designs. Basic components can be printed for (in some cases) less than 1/100th costs of conventional manufacturing. We have examined the impact that AM can have on plasma diagnostic cost by taking 15 separate diagnostics through an engineering design using Conventional Manufacturing (CM) techniques to determine costs of components and labor costs associated with getting the diagnostic to work as intended. With that information in hand, we set about optimizing the design to exploit the benefits of AM. Work performed under DOE Contract DE-SC0011858.

Hydropower Manufacturing and Supply Chain Analysis

Energy Technology Data Exchange (ETDEWEB)

Cotrell, Jason R [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

2018-01-02

Hydropower Manufacturing and Supply Chain Analysis presentation from the WPTO FY14-FY16 Peer Review. The project objective is to provide data and insights to inform investment strategies, policy, and other decisions to promote economic growth and manufacturing.

Manufacture of Probiotic Bacteria

Science.gov (United States)

Muller, J. A.; Ross, R. P.; Fitzgerald, G. F.; Stanton, C.

Lactic acid bacteria (LAB) have been used for many years as natural biopreservatives in fermented foods. A small group of LAB are also believed to have beneficial health effects on the host, so called probiotic bacteria. Probiotics have emerged from the niche industry from Asia into European and American markets. Functional foods are one of the fastest growing markets today, with estimated growth to 20 billion dollars worldwide by 2010 (GIA, 2008). The increasing demand for probiotics and the new food markets where probiotics are introduced, challenges the industry to produce high quantities of probiotic cultures in a viable and stable form. Dried concentrated probiotic cultures are the most convenient form for incorporation into functional foods, given the ease of storage, handling and transport, especially for shelf-stable functional products. This chapter will discuss various aspects of the challenges associated with the manufacturing of probiotic cultures.

Research Staff | Advanced Manufacturing Research | NREL

Science.gov (United States)

manages wind turbine rotor blade composite manufacturing projects at the National Wind Technology Center postdoctoral researcher working to develop and validate advanced composite manufacturing processes using novel materials for wind and marine and hydrokinetic (MHK) turbines. This includes hands-on composite

Zambian manufacturing performance in comparative perspective

NARCIS (Netherlands)

Yamfwa, F.K.; Szirmai, A.; Lwamba, C.

2002-01-01

This paper presents an analysis of Zambian manufacturing performance since 1964. It presents new estimates of labour productivity growth and total factor productivity growth. After a period of growth and labour productivity improvement till 1974, Zambian manufacturing suffered from increasing

Measures to increase the UK-manufactured content of wind turbines

International Nuclear Information System (INIS)

1996-01-01

Little formal work has been undertaken on the subject of component supply. Garrad Hassan (GH) has provided consultancy services to the UK and international wind energy industry, including almost all European wind turbine manufacturers, for more than a decade. Most of this report is based on that experience. Over this period, a good understanding of the market for wind turbines and the associated components has developed. (author)

78 FR 63964 - Meeting of the Manufacturing Council

Science.gov (United States)

2013-10-25

... DEPARTMENT OF COMMERCE International Trade Administration Meeting of the Manufacturing Council AGENCY: International Trade Administration, U.S. Department of Commerce. ACTION: Notice of an open... subcommittees on workforce development and public perception of manufacturing; manufacturing energy policy; tax...

USABILITY OF ADDITIVE MANUFACTURING (THREEDIMENSIONAL PRINTING) TECHNOLOGIES IN EDUCATION

OpenAIRE

ÖZSOY, KORAY; DUMAN, BURHAN

2017-01-01

Additive manufacturing technologies which are emerge in 1980’s years, they are using for prototip production in first time for that reason their denomination rapid prototyping . Nowadays it called additive manufacturing because of it using for end use functional part’s production. In additive manufacturing, the basic rationales the same, but many different technologies have been developed to manufacture with different approaches. The most common additive manufacturing technologies are stereol...

Cybersecurity for industry 4.0 analysis for design and manufacturing

CERN Document Server

Schaefer, Dirk

2017-01-01

This book introduces readers to cybersecurity and its impact on the realization of the Industry 4.0 vision. It covers the technological foundations of cybersecurity within the scope of the Industry 4.0 landscape and details the existing cybersecurity threats faced by Industry 4.0, as well as state-of-the-art solutions with regard to both academic research and practical implementations. Industry 4.0 and its associated technologies, such as the Industrial Internet of Things and cloud-based design and manufacturing systems are examined, along with their disruptive innovations. Further, the book analyzes how these phenomena capitalize on the economies of scale provided by the Internet. The book offers a valuable resource for practicing engineers and decision makers in industry, as well as researchers in the design and manufacturing communities and all those interested in Industry 4.0 and cybersecurity.

'Serial review on clinical PET tracers'. Manufacturing and quality control of positron emitting radiopharmaceuticals produced by in-house cyclotron

International Nuclear Information System (INIS)

Saji, Hideo

2009-01-01

In order to establish PET diagnosis as a routine clinical tool, manufacture's compliance with regulations under the Good Manufacturing Practice (GMP) principle for PET radiopharmaceuticals is necessary. For this purpose, the Sub-committee on Medical Application of Positron Emitting Radionuclides, Medical Science and Pharmaceutical Committee of Japan Radioisotopes Association has proposed 'Standards for Compounds Labeled with Emitting Radionuclides Approved as Established Techniques for Medical Use'. This guideline includes the general notices, general rules for preparations, general tests for the quality control, quality of each PET agents, guideline for manufacturing environment and manufacturing process at manufacturing facilities of PET agents. Each facility should have a committee and establish an internal system to account for manufacturing compounds labeled with positron emitting radionuclides produced in the facility, and compile standards by referring to the 'Established Standard Techniques of Labeling Compounds with Emitting Radionuclides for use as Radiopharmaceuticals: approved by the Subcommittee on Medical Application of Cyclotron-Produced Radionuclides (revised in 2009)', in order to maintain the quality of radiopharmaceuticals. (author)

Assessing the Importance of Domestic Vaccine Manufacturing Centers: An Overview of Immunization Programs, Vaccine Manufacture, and Distribution

Directory of Open Access Journals (Sweden)

Emma Rey-Jurado

2018-01-01

Full Text Available Vaccines have significantly reduced the detrimental effects of numerous human infectious diseases worldwide, helped to reduce drastically child mortality rates and even achieved eradication of major pathogens, such as smallpox. These achievements have been possible due to a dedicated effort for vaccine research and development, as well as an effective transfer of these vaccines to public health care systems globally. Either public or private institutions have committed to developing and manufacturing vaccines for local or international population supply. However, current vaccine manufacturers worldwide might not be able to guarantee sufficient vaccine supplies for all nations when epidemics or pandemics events could take place. Currently, different countries produce their own vaccine supplies under Good Manufacturing Practices, which include the USA, Canada, China, India, some nations in Europe and South America, such as Germany, the Netherlands, Italy, France, Argentina, and Brazil, respectively. Here, we discuss some of the vaccine programs and manufacturing capacities, comparing the current models of vaccine management between industrialized and developing countries. Because local vaccine production undoubtedly provides significant benefits for the respective population, the manufacture capacity of these prophylactic products should be included in every country as a matter of national safety.

Assessing the Importance of Domestic Vaccine Manufacturing Centers: An Overview of Immunization Programs, Vaccine Manufacture, and Distribution.

Science.gov (United States)

Rey-Jurado, Emma; Tapia, Felipe; Muñoz-Durango, Natalia; Lay, Margarita K; Carreño, Leandro J; Riedel, Claudia A; Bueno, Susan M; Genzel, Yvonne; Kalergis, Alexis M

2018-01-01

Vaccines have significantly reduced the detrimental effects of numerous human infectious diseases worldwide, helped to reduce drastically child mortality rates and even achieved eradication of major pathogens, such as smallpox. These achievements have been possible due to a dedicated effort for vaccine research and development, as well as an effective transfer of these vaccines to public health care systems globally. Either public or private institutions have committed to developing and manufacturing vaccines for local or international population supply. However, current vaccine manufacturers worldwide might not be able to guarantee sufficient vaccine supplies for all nations when epidemics or pandemics events could take place. Currently, different countries produce their own vaccine supplies under Good Manufacturing Practices, which include the USA, Canada, China, India, some nations in Europe and South America, such as Germany, the Netherlands, Italy, France, Argentina, and Brazil, respectively. Here, we discuss some of the vaccine programs and manufacturing capacities, comparing the current models of vaccine management between industrialized and developing countries. Because local vaccine production undoubtedly provides significant benefits for the respective population, the manufacture capacity of these prophylactic products should be included in every country as a matter of national safety.

78 FR 77426 - Meeting of the Manufacturing Council

Science.gov (United States)

2013-12-23

... DEPARTMENT OF COMMERCE International Trade Administration Meeting of the Manufacturing Council AGENCY: International Trade Administration, U.S. Department of Commerce. ACTION: Notice of an Open... development and public perception of manufacturing; manufacturing energy policy; tax policy and export growth...

19 CFR 191.24 - Certificate of manufacture and delivery.

Science.gov (United States)

2010-04-01

... Section 191.24 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY... manufactured or produced under a general manufacturing drawback ruling, the unique computer-generated number... manufactured or produced under a specific manufacturing drawback ruling, either the unique computer number or...

COMPONENTS PROVISION MANAGEMENT FOR MACHINE BUILDING MANUFACTURER

Directory of Open Access Journals (Sweden)

Ekaterina P. Bochkareva

2014-01-01

Full Text Available In the paper is given an approach to themanagement of components provision formachine building manufacturer based uponinternational standards and best practicesof leading international companies. Thecomplex expertise methods are used forthe development of the proposed machinebuilding manufacturer suppliers’ operational management method. At a strategic level is proposed a tool for planning the suppliers’portfolio and a machine building manufacturer supplier development methodology.

Advanced Manufacturing Processes Laboratory Building 878 hazards assessment document

Energy Technology Data Exchange (ETDEWEB)

Wood, C.; Thornton, W.; Swihart, A.; Gilman, T.

1994-07-01

The introduction of the hazards assessment process is to document the impact of the release of hazards at the Advanced Manufacturing Processes Laboratory (AMPL) that are significant enough to warrant consideration in Sandia National Laboratories` operational emergency management program. This hazards assessment is prepared in accordance with the Department of Energy Order 5500.3A requirement that facility-specific hazards assessments be prepared, maintained, and used for emergency planning purposes. This hazards assessment provides an analysis of the potential airborne release of chemicals associated with the operations and processes at the AMPL. This research and development laboratory develops advanced manufacturing technologies, practices, and unique equipment and provides the fabrication of prototype hardware to meet the needs of Sandia National Laboratories, Albuquerque, New Mexico (SNL/NM). The focus of the hazards assessment is the airborne release of materials because this requires the most rapid, coordinated emergency response on the part of the AMPL, SNL/NM, collocated facilities, and surrounding jurisdiction to protect workers, the public, and the environment.

Advanced Manufacturing Processes Laboratory Building 878 hazards assessment document

International Nuclear Information System (INIS)

Wood, C.; Thornton, W.; Swihart, A.; Gilman, T.

1994-07-01

The introduction of the hazards assessment process is to document the impact of the release of hazards at the Advanced Manufacturing Processes Laboratory (AMPL) that are significant enough to warrant consideration in Sandia National Laboratories' operational emergency management program. This hazards assessment is prepared in accordance with the Department of Energy Order 5500.3A requirement that facility-specific hazards assessments be prepared, maintained, and used for emergency planning purposes. This hazards assessment provides an analysis of the potential airborne release of chemicals associated with the operations and processes at the AMPL. This research and development laboratory develops advanced manufacturing technologies, practices, and unique equipment and provides the fabrication of prototype hardware to meet the needs of Sandia National Laboratories, Albuquerque, New Mexico (SNL/NM). The focus of the hazards assessment is the airborne release of materials because this requires the most rapid, coordinated emergency response on the part of the AMPL, SNL/NM, collocated facilities, and surrounding jurisdiction to protect workers, the public, and the environment

Economic implications of manufacturing sawed ties and timbers

Science.gov (United States)

Lawrence D. Garrett; Lawrence D. Garrett

1969-01-01

The purpose of this paper is to discuss those factors that affect the profitability of manufacturing timbers and show that the combined manufacture of both lumber and timbers will provide a greater daily income than the manufacture of lumber alone.

40 CFR 763.165 - Manufacture and importation prohibitions.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Manufacture and importation...) TOXIC SUBSTANCES CONTROL ACT ASBESTOS Prohibition of the Manufacture, Importation, Processing, and Distribution in Commerce of Certain Asbestos-Containing Products; Labeling Requirements § 763.165 Manufacture...

Manufacturing and testing of full scale prototype for ITER blanket shield block

Energy Technology Data Exchange (ETDEWEB)

Kim, Sa-Woong, E-mail: swkim12@nfri.re.kr [ITER Korea, National Fusion Research Institute, Daejeon (Korea, Republic of); Kim, Duck-Hoi; Jung, Hun-Chea [ITER Korea, National Fusion Research Institute, Daejeon (Korea, Republic of); Lee, Sung-Ki [WONIL Co., Ltd., Haman (Korea, Republic of); Kang, Sung-Chan [POSCO Specialty Steel Co., Ltd., Changwon (Korea, Republic of); Zhang, Fu; Kim, Byoung-Yoon [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul Lez Durance (France); Ahn, Hee-Jae; Lee, Hyeon-Gon; Jung, Ki-Jung [ITER Korea, National Fusion Research Institute, Daejeon (Korea, Republic of)

2015-04-15

Highlights: • 316L(N)-IG forged steel was successfully fabricated and qualified. • Related R&D activities were implemented to resolve the fabrication issues. • SB #8 FSP was successfully manufactured with conventional fabrication techniques. • All of the validation tests were carried out and met the acceptance criteria. - Abstract: Based on the preliminary design of the ITER blanket shield block (SB) #8, the full scale prototype (FSP) has been manufactured and tested in accordance with pre-qualification program, and related R&D was performed to resolve the technical issues of fabrication. The objective of the SB pre-qualification program is to demonstrate the acceptable manufacturing quality by successfully passing the formal test program. 316L(N)-IG stainless steel forging blocks with 1.80L × 1.12W × 0.43t (m) were developed by using an electric arc furnace, and as a result, the material properties were satisfied with technical specification. In the course of applying conventional fabrication techniques such as cutting, milling, drilling and welding of the forged stainless steel block for the manufacturing of the SB #8 FSP, several technical problems have been addressed. And also, the hydraulic connector of cross-forged material re-melted by electro slag or vacuum arc requires the application of advanced joining techniques such as automatic bore TIG and friction welding. Many technical issues – drilling, welding, slitting, non-destructive test and so on – have been raised during manufacturing. Associated R&D including the computational simulation and coupon testing has been done in collaboration with relevant industries in order to resolve these engineering issues. This paper provides technical key issues and their possible resolutions addressed during the manufacture and formal test of the SB #8 FSP, and related R&D.

Anxiety symptoms and occupational stress among young Korean female manufacturing workers.

Science.gov (United States)

Lee, Kang Ho; Ho Chae, Chang; Ouk Kim, Young; Seok Son, Jun; Kim, Ja-Hyun; Woo Kim, Chan; Ouk Park, Hyoung; Ho Lee, Jun; Saeng Jung, Young

2015-01-01

The prevalence of anxiety disorders has been increasing in South Korea, with recent studies reporting anxiety disorders as the most common mental disorder among all South Korean females. Anxiety disorders, which are independent risk factors of suicidal ideation and suicide attempts, are significantly correlated with productivity loss, high medical costs, impaired work performance, and frequent worker absence, and thus are potentially serious problems affecting the health of South Korean female workers. In previous studies, anxiety disorders were shown to have a significant correlation with occupational stress. This study seeks to examine the prevalence of anxiety symptoms as well as the relationship between occupational stress and anxiety symptoms among South Korean female manufacturing workers. A structured self-reported questionnaire was administered to 1,141 female workers at an electrical appliance manufacturing plant. The questionnaire collected data on general characteristics, health behaviors, sleep quality, job characteristics (shift work, shift work schedule, and job tenure), occupational stress, and anxiety symptoms. Sleep quality was measured using the Pittsburgh Sleep Quality Index, occupational stress with the Korean Occupational Stress Scale-Short Form (KOSS-SF), and anxiety symptoms with the Korean version of the Beck Anxiety Inventory. A chi square test was conducted to determine the distribution differences in anxiety symptoms based on general characteristics, health behaviors, job characteristics, and sleep quality. A linear-by-linear association test was used to determine the distribution differences between anxietysymptoms and the levels of occupational stress. Last, logistic regression analysis was used in order to determine the association between occupational stress and anxiety symptoms. The prevalence of anxiety symptoms was 15.2 %. In the multivariate logistic regression analysis that adjusted for sleep quality and general characteristics

Tracing and control of raw materials sourcing for vaccine manufacturers.

Science.gov (United States)

Faretra Peysson, Laurence

2010-05-01

The control of the raw materials used to manufacture vaccines is mandatory; therefore, a very clear process must be in place to guarantee that raw materials are traced. Those who make products or supplies used in vaccine manufacture (suppliers of culture media, diagnostic tests, etc.) must apply quality systems proving that they adhere to certain standards. ISO certification, Good Manufacturing Practices for production sites and the registration of culture media with a 'Certificate of Suitability' from the European Directorate for the Quality of Medicines and Healthcare are reliable quality systems pertaining to vaccine production. Suppliers must assure that each lot of raw materials used in a product that will be used in vaccine manufacture adheres to the level of safety and traceability required. Incoming materials must be controlled in a single 'Enterprise Resource Planning' system which is used to document important information, such as the assignment of lot number, expiration date, etc. Ingredients for culture media in particular must conform to certain specifications. The specifications that need to be checked vary according to the ingredient, based on the level of risk. The way a raw material is produced is also important, and any aspect relative to cross-contamination, such as the sanitary measures used in producing and storing the raw material must be checked as well. In addition, suppliers can reduce the risk of viral contamination of raw materials by avoiding purchases in countries where a relevant outbreak is currently declared. 2010 The International Association for Biologicals. Published by Elsevier Ltd. All rights reserved.

In-Space Manufacturing Baseline Property Development

Science.gov (United States)

Stockman, Tom; Schneider, Judith; Prater, Tracie; Bean, Quincy; Werkheiser, Nicki

2016-01-01

The In-Space Manufacturing (ISM) project at NASA Marshall Space Flight Center currently operates a 3D FDM (fused deposition modeling) printer onboard the International Space Station. In order to enable utilization of this capability by designer, the project needs to establish characteristic material properties for materials produced using the process. This is difficult for additive manufacturing since standards and specifications do not yet exist for these technologies. Due to availability of crew time, there are limitations to the sample size which in turn limits the application of the traditional design allowables approaches to develop a materials property database for designers. In this study, various approaches to development of material databases were evaluated for use by designers of space systems who wish to leverage in-space manufacturing capabilities. This study focuses on alternative statistical techniques for baseline property development to support in-space manufacturing.

Current manufacturing processes of drug-eluting sutures.

Science.gov (United States)

Champeau, Mathilde; Thomassin, Jean-Michel; Tassaing, Thierry; Jérôme, Christine

2017-11-01

Drug-eluting sutures represent the next generation of surgical sutures since they fulfill their mechanical functions but also deliver the drug in their vicinity after implantation. These implants are produced by a variety of manufacturing processes. Drug-eluting sutures represent the next generation of surgical sutures since they fulfill their mechanical functions but also deliver the drug in their vicinity after implantation. These implants are produced by a variety of manufacturing processes. Two general approaches can be followed: (i) the ones that add the API into the material during the manufacturing process of the suture and (ii) the ones that load the API to an already manufactured suture. Areas covered: This review provides an overview of the current manufacturing processes for drug-eluting suture production and discusses their benefits and drawbacks depending on the type of drugs. The mechanical properties and the drug delivery profile of drug-eluting sutures are highlighted since these implants must fulfill both criteria. Expert opinion: For limited drug contents, melt extrusion and electrospinning are the emerging processes since the drug is added during the suture manufacture process. Advantageously, the drug release profile can be tuned by controlling the processing parameters specific to each process and the composition of the drug-containing polymer. If high drug content is targeted, the coating or grafting of a drug layer on a pre-manufactured suture allows for preservation of the tensile strength requirements of the suture.

Development of Manufacturing Technology to Accelerate Cost Reduction of Low Concentration and

Energy Technology Data Exchange (ETDEWEB)

Detrick, Adam [The Solaria Corporation, Fremont, CA (United States)

2017-09-27

is currently positioned to become the market leader with these two technologies over the coming 24 months largely due to the successful innovations of the underlying manufacturing technology. This success will leverage US-based manufacturing technology and the associated US-jobs to support. Solaria views the project as highly successful and a great example of SunShot funding enabling the creating of US jobs and the deployment of ubiquitous solar energy products.

Asbestos manufacturing plants in Poland

Directory of Open Access Journals (Sweden)

Wilk Ewa

2014-06-01

Full Text Available The unique set of physical and chemical properties of asbestos has led to its many industrial applications, such as roof coverings, textiles, rope, cord and yarn, paper, friction and composition materials, household product, acid-resistant filters, packing, insulation, and certain types of lagging, amongst others. In Poland asbestos-containing products were manufactured from raw materials imported mainly from the former Soviet Union, with production launched at the beginning of 20th century. According to Annex 4 to the Act of 19 June 1997 on the prohibition of the use of asbestos-containing products, there were 28 asbestos manufacturing plants in Poland located in 11 provinces throughout the country. The current survey was undertaken to enable asbestos manufacturing plants to be arranged, described and divided in order to contribute to further surveys.

Additive Manufacturing: Multi Material Processing and Part Quality Control

DEFF Research Database (Denmark)

Pedersen, David Bue

This Ph.D dissertation,ffAdditive Manufacturing: Multi Material Processing and Part Quality Controlff, deal with Additive Manufacturing technologies which is a common name for a series of processes that are recognized by being computer controlled, highly automated, and manufacture objects...... by a layered deposition of material. Two areas of particular interest is addressed. They are rooted in two very different areas, yet is intended to fuel the same goal. To help Additive Manufacturing technologies one step closer to becoming the autonomous, digital manufacturing method of tomorrow. Vision...... systems A paradox exist in the field of Additive Manufacturing. The technologies allow for close-to unrestrained and integral geometrical freedom. Almost any geometry can be manufactured fast, e"ciently and cheap. Something that has been missing fundamental capability since the entering of the industrial...

Potential of Continuous Manufacturing for Liposomal Drug Products.

Science.gov (United States)

Worsham, Robert D; Thomas, Vaughan; Farid, Suzanne S

2018-05-21

Over the last several years, continuous manufacturing of pharmaceuticals has evolved from bulk APIs and solid oral dosages into the more complex realm of biologics. The development of continuous downstream processing techniques has allowed biologics manufacturing to realize the benefits (e.g. improved economics, more consistent quality) that come with continuous processing. If relevant processing techniques and principles are selected, the opportunity arises to develop continuous manufacturing designs for additional pharmaceutical products including liposomal drug formulations. Liposome manufacturing has some inherent aspects that make it favorable for a continuous process. Other aspects such as formulation refinement, materials of construction, and aseptic processing need development, but present an achievable challenge. This paper reviews the current state of continuous manufacturing technology applicable to liposomal drug product manufacturing and an assessment of the challenges and potential of this application. This article is protected by copyright. All rights reserved.

Research on Green Manufacturing Innovation Based on Resource Environment Protection

Science.gov (United States)

Jie, Xu

2017-11-01

Green manufacturing is a trend of manufacturing industry in the future, and is of great significance to resource protection and environmental protection. This paper first studies the green manufacturing innovation system, and then decomposes the green manufacturing innovation dimensions, and constructs the green manufacturing innovation dimension space. Finally, from the view of resource protection and environmental protection, this paper explores the path of green manufacturing innovation.

21 CFR 1005.25 - Service of process on manufacturers.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Service of process on manufacturers. 1005.25....25 Service of process on manufacturers. (a) Every manufacturer of electronic products, prior to... United States as the manufacturer's agent upon whom service of all processes, notices, orders, decisions...

Legal aspects of the clean-up and reclamation of the manufactured gas plants

Energy Technology Data Exchange (ETDEWEB)

Joldzic, V. [Belgrade University, Belgrade (Yugoslavia). Inst. for Criminology and Sociological Research

1995-12-31

The laws associated with the cleanup of manufactured gas plants in Yugoslavia is described. These comprise the Environmental Protection Act; the Law about Space Planning and Organizing; Building Law; and Agricultural Land Use Law. Joint remedial action in the Danube Basin is discussed. 13 refs.

Advanced manufacturing: Technology diffusion

Energy Technology Data Exchange (ETDEWEB)

Tesar, A.

1995-12-01

In this paper we examine how manufacturing technology diffuses rom the developers of technology across national borders to those who do not have the capability or resources to develop advanced technology on their own. None of the wide variety of technology diffusion mechanisms discussed in this paper are new, yet the opportunities to apply these mechanisms are growing. A dramatic increase in technology diffusion occurred over the last decade. The two major trends which probably drive this increase are a worldwide inclination towards ``freer`` markets and diminishing isolation. Technology is most rapidly diffusing from the US In fact, the US is supplying technology for the rest of the world. The value of the technology supplied by the US more than doubled from 1985 to 1992 (see the Introduction for details). History shows us that technology diffusion is inevitable. It is the rates at which technologies diffuse to other countries which can vary considerably. Manufacturers in these countries are increasingly able to absorb technology. Their manufacturing efficiency is expected to progress as technology becomes increasingly available and utilized.

Challenges in Teaching Modern Manufacturing Technologies

Science.gov (United States)

Ngaile, Gracious; Wang, Jyhwen; Gau, Jenn-Terng

2015-01-01

Teaching of manufacturing courses for undergraduate engineering students has become a challenge due to industrial globalisation coupled with influx of new innovations, technologies, customer-driven products. This paper discusses development of a modern manufacturing course taught concurrently in three institutions where students collaborate in…

An In-Depth Review on Direct Additive Manufacturing of Metals

Science.gov (United States)

Azam, Farooq I.; Rani, Ahmad Majdi Abdul; Altaf, Khurram; Rao, T. V. V. L. N.; Aimi Zaharin, Haizum

2018-03-01

Additive manufacturing (AM), also known as 3D Printing, is a revolutionary manufacturing technique which has been developing rapidly in the last 30 years. The evolution of this precision manufacturing process from rapid prototyping to ready-to-use parts has significantly alleviated manufacturing constraints and design freedom has been outstandingly widened. AM is a non-conventional manufacturing technique which utilizes a 3D CAD model data to build parts by adding one material layer at a time, rather than removing it and fulfills the demand for manufacturing parts with complex geometric shapes, great dimensional accuracy, and easy to assemble parts. Additive manufacturing of metals has become the area of extensive research, progressing towards the production of final products and replacing conventional manufacturing methods. This paper provides an insight to the available metal additive manufacturing technologies that can be used to produce end user products without using conventional manufacturing methods. The paper also includes the comparison of mechanical and physical properties of parts produced by AM with the parts manufactured using conventional processes.

Advances in High Temperature Materials for Additive Manufacturing

Science.gov (United States)

Nordin, Nurul Amira Binti; Johar, Muhammad Akmal Bin; Ibrahim, Mohd Halim Irwan Bin; Marwah, Omar Mohd Faizan bin

2017-08-01

In today’s technology, additive manufacturing has evolved over the year that commonly known as 3D printing. Currently, additive manufacturing have been applied for many industries such as for automotive, aerospace, medical and other commercial product. The technologies are supported by materials for the manufacturing process to produce high quality product. Plus, additive manufacturing technologies has been growth from the lowest to moderate and high technology to fulfil manufacturing industries obligation. Initially from simple 3D printing such as fused deposition modelling (FDM), poly-jet, inkjet printing, to selective laser sintering (SLS), and electron beam melting (EBM). However, the high technology of additive manufacturing nowadays really needs high investment to carry out the process for fine products. There are three foremost type of material which is polymer, metal and ceramic used for additive manufacturing application, and mostly they were in the form of wire feedstock or powder. In circumstance, it is crucial to recognize the characteristics of each type of materials used in order to understand the behaviours of the materials on high temperature application via additive manufacturing. Therefore, this review aims to provide excessive inquiry and gather the necessary information for further research on additive material materials for high temperature application. This paper also proposed a new material based on powder glass, which comes from recycled tempered glass from automotive industry, having a huge potential to be applied for high temperature application. The technique proposed for additive manufacturing will minimize some cost of modelling with same quality of products compare to the others advanced technology used for high temperature application.

Using Innovative Techniques for Manufacturing Rocket Engine Hardware

Science.gov (United States)

Betts, Erin M.; Reynolds, David C.; Eddleman, David E.; Hardin, Andy

2011-01-01

Many of the manufacturing techniques that are currently used for rocket engine component production are traditional methods that have been proven through years of experience and historical precedence. As we enter into a new space age where new launch vehicles are being designed and propulsion systems are being improved upon, it is sometimes necessary to adopt new and innovative techniques for manufacturing hardware. With a heavy emphasis on cost reduction and improvements in manufacturing time, manufacturing techniques such as Direct Metal Laser Sintering (DMLS) are being adopted and evaluated for their use on J-2X, with hopes of employing this technology on a wide variety of future projects. DMLS has the potential to significantly reduce the processing time and cost of engine hardware, while achieving desirable material properties by using a layered powder metal manufacturing process in order to produce complex part geometries. Marshall Space Flight Center (MSFC) has recently hot-fire tested a J-2X gas generator discharge duct that was manufactured using DMLS. The duct was inspected and proof tested prior to the hot-fire test. Using the Workhorse Gas Generator (WHGG) test setup at MSFC?s East Test Area test stand 116, the duct was subject to extreme J-2X gas generator environments and endured a total of 538 seconds of hot-fire time. The duct survived the testing and was inspected after the test. DMLS manufacturing has proven to be a viable option for manufacturing rocket engine hardware, and further development and use of this manufacturing method is recommended.

Computer-Aided Manufacturing of 3D Workpieces

OpenAIRE

Cornelia Victoria Anghel Drugarin; Mihaela Dorica Stroia

2017-01-01

Computer-Aided Manufacturing (CAM) assumes to use dedicated software for controlling machine tools and similar devices in the process of workpieces manufacturing. CAM is, in fact, an application technology that uses computer software and machinery to simplify and automate manufacturing processes. CAM is the inheritor of computer-aided engineering (CAE) and is often used conjunctively with computer-aided design (CAD). Advanced CAM solutions are forthcoming and have a large ...

TORE SUPRA vacuum vessel and shield manufacturing

International Nuclear Information System (INIS)

Blateyron, J.; Lepez, R.

1984-01-01

TORE SUPRA vacuum vessel and vacuum chamber shield manufacturing in progress at Jeumont-Schneider consists of three main phases: - Detail engineering and manufacturing fixture construction; - Prototype section manufacturing and process preparation; - Construction of the 6 production modules. The welding techniques adopted, call for three special automatic processes: TIG, MIG and PLASMA welding which guarantee mechanical strength, vacuum tightness and absence of distortion. Production of the modules began July 1984. (author)

Cost Accounting in the Automated Manufacturing Environment

Science.gov (United States)

1988-06-01

1 NAVAL POSTGRADUATE SCHOOL M terey, California 0 DTIC II ELECTE R AD%$° NO 0,19880 -- THESIS COST ACCOUNTING IN THE AUTOMATED MANUFACTURING...PROJECT TASK WORK UNIT ELEMENT NO. NO NO ACCESSION NO 11. TITLE (Include Security Classification) E COST ACCOUNTING IN THE AUTOMATED MANUFACTURING...GROUP ’" Cost Accounting ; Product Costing ; Automated Manufacturing; CAD/CAM- CIM 19 ABSTRACT (Continue on reverse if necessary and identify by blo

Lean management in a non-manufacturing organization

Directory of Open Access Journals (Sweden)

Mladen Žvorc

2013-12-01

Full Text Available This paper examines the possibilities of a lean approach to non-manufacturing functions, i.e. a market-oriented organization. This refers to purchasing, shipment, storage, sale and delivery of goods; marketing, etc. A lean approach to business operations is discussed and several lean business methods are developed on the basis of which lean management can be used not only in manufacturing, but also in non-manufacturing organizations.

48 CFR 235.006-70 - Manufacturing Technology Program.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Manufacturing Technology... CONTRACTING 235.006-70 Manufacturing Technology Program. In accordance with 10 U.S.C. 2521(d), for acquisitions under the Manufacturing Technology Program— (a) Award all contracts using competitive procedures...

Survey of US Department of Defense Manufacturing Technology Program activities applicable to civilian manufacturing industries. Final report

Energy Technology Data Exchange (ETDEWEB)

Azimi, S.A.; Conrad, J.L.; Reed, J.E.

1985-03-01

Intent of the survey was to identify and characterize activities potentially applicable to improving energy efficiency and overall productivity in the civilian manufacturing industries. The civilian industries emphasized were the general manufacturing industries (including fabricated metals, glass, machinery, paper, plastic, textile, and transportation equipment manufacturing) and the primary metals industries (including primary aluminum, copper, steel, and zinc production). The principal steps in the survey were to: develop overview taxonomies of the general manufacturing and primary metals industries as well as specific industry taxonomies; identify needs and opportunities for improving process energy efficiency and productivity in the industries included; identify federal programs, capabilities, and special technical expertise that might be relevant to industry's needs and opportunities; contact federal laboratories/facilities, through visits and other forms of inquiry; prepare formatted profiles (descriptions) potentially applicable work efforts; review findings with industry; and compile and evaluate industry responses.

How development and manufacturing will need to be structured--heads of development/manufacturing. May 20-21, 2014 Continuous Manufacturing Symposium.

Science.gov (United States)

Nepveux, Kevin; Sherlock, Jon-Paul; Futran, Mauricio; Thien, Michael; Krumme, Markus

2015-03-01

, because of stability constraints or individualization to patients, do not allow centralized manufacturing approaches at all. Again, the entire enterprise needs to be restructured accordingly. The situation of CM in an outsourced operation business model is discussed. Next steps for the industry are recommended. In summary, opportunistic implementation of isolated steps in existing portfolios can be implemented with minimal organizational changes; the availability of the appropriate skills is the determining factor. The implementation of more substantial sequences requires business processes that consider the portfolio, not just single products. Exploration and implementation of complete process chains with consequences for quality decisions do require appropriate organizational support. © 2015 Wiley Periodicals, Inc. and the American Pharmacists Association.

Issues at manufactured gas plant sites

International Nuclear Information System (INIS)

Menzie, C.A.; Unites, D.F.; Nakles, D.

1991-01-01

Gas, manufactured from coal or oil was used to light and heat homes, industries, and streets of this country from the mid-1800s to the late 1940s or early 1950s. The era, with its associated gas lights, faded with the development of natural gas supplies and direct use of other fossil fuels. Today, Manufactured Gas Plant (MGP) sites are part of our history. Most of the MGPs were operated at a time when the state of the environmental sciences was much less sophisticated and the environmental regulations were much less stringent or nonexistent. While there was an awareness of potential environmental problems then the concerns were more qualitative (e.g., odor, color) and resulted in minimal treatment of process residuals. Inasmuch as there may be over a thousand MGP sites in the United States, it also became clear that utility research institutes such as the Gas Research Institute (GRI) and the Electric Power Research Institute (EPRI) should address key research and management issues related to site investigation, risk assessment, and site remediation. Information gained from these research initiatives would serve the industry as a whole, as well as other groups involved in the assessment of MGP sites. This paper provides and overview of these programs and identifies how additional information can be obtained

Computer-assisted nuclear fuel manufacture

International Nuclear Information System (INIS)

Maloney, J.P.; Schaumann, S.M.; Stone, E.

1976-01-01

At the ERDA Savannah River Plant, a process monitor, which incorporates an online digital computer, assists in manufacturing fuel elements used to produce nuclides such as plutonium, tritium, and californium in the plant's nuclear reactors. Also, inventory functions assist in safeguarding fissile material and protecting against accidental nuclear criticality. Terminals at strategic locations throughout the process area enable production operators to send and receive instructions and information on each manufacturing step

Design and Evaluation of a Reconfigurable Manufacturing System

DEFF Research Database (Denmark)

Zhang, Shuai; Li, Yang; Bilberg, Arne

2014-01-01

In modern manufacturing industry, reconfigurable manufacturing system (RMS) is a promising concept in the research arena. A new RMS system structure has been recently designed by a large consumer goods manufacturer in Europe, aiming to improve its production efficiency. This article shows...... implemented in this consumer goods manufacturer can be effectively (re)configured as part of the daily operations, and the configuration is analyzed by computer simulation before release. Flexibility can be increased considerably meanwhile the system can maintain an acceptable productivity....

Additive manufacturing: From implants to organs

African Journals Online (AJOL)

Additive manufacturing (AM) constructs 3D objects layer by layer under computer control from 3D models. 3D printing is one ... anatomical models for surgery planning, and design and construction ... production of implants, particularly to replace bony structures, is ... Manufactured organs are, however, an elusive goal.

49 CFR 178.33-6 - Manufacture.

Science.gov (United States)

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Manufacture. 178.33-6 Section 178.33-6 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY... Specifications for Inside Containers, and Linings § 178.33-6 Manufacture. (a) By appliances and methods that will...

49 CFR 178.360-2 - Manufacture.

Science.gov (United States)

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Manufacture. 178.360-2 Section 178.360-2 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY... Specifications for Packagings for Class 7 (Radioactive) Materials § 178.360-2 Manufacture. The ends of the vessel...

49 CFR 529.6 - Requirements for final-stage manufacturers.

Science.gov (United States)

2010-10-01

... paragraph (a)(1) of this section, that manufacturer shall prepare a new fuel economy label for that... manufacturer shall attach the fuel economy label furnished by the incomplete automobile manufacturer under § 529.4(c)(2) or by the last intermediate manufacturer under § 529.5(d)(2) or the fuel economy label...

Toward Meaningful Manufacturing Variation Data in Design - Feature Based Description of Variation in Manufacturing Processes

DEFF Research Database (Denmark)

Eifler, Tobias; Boorla, Srinivasa Murthy; Howard, Thomas J.

2016-01-01

The need to mitigate the effects of manufacturing variation already in design is nowadays commonly acknowledged and has led to a wide use of predictive modeling techniques, tolerancing approaches, etc. in industry. The trustworthiness of corresponding variation analyses is, however, not ensured...... by the availability of sophisticated methods and tools alone, but does evidently also depend on the accuracy of the input information used. As existing approaches for the description of manufacturing variation focus however, almost exclusively, on monitoring and controlling production processes, there is frequently...... a lack of objective variation data in design. As a result, variation analyses and tolerancing activities rely on numerous assumptions made to fill the gaps of missing or incomplete data. To overcome this hidden subjectivity, a schema for a consistent and standardised description of manufacturing...

14 CFR 35.17 - Materials and manufacturing methods.

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Materials and manufacturing methods. 35.17... AIRWORTHINESS STANDARDS: PROPELLERS Design and Construction § 35.17 Materials and manufacturing methods. (a) The... and manufacturing methods must conform to specifications acceptable to the Administrator. (c) The...

21 CFR 680.2 - Manufacture of Allergenic Products.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Manufacture of Allergenic Products. 680.2 Section...) BIOLOGICS ADDITIONAL STANDARDS FOR MISCELLANEOUS PRODUCTS § 680.2 Manufacture of Allergenic Products. (a...) Cultures derived from microorganisms. Culture media into which organisms are inoculated for the manufacture...

Manufacturing and service opportunities for Canadian companies in large wind turbines

International Nuclear Information System (INIS)

Wittholz, H.; Lacroix, A.