Implementing the Espoo Convention in transboundary EIA between Germany and Poland

International Nuclear Information System (INIS)

Albrecht, Eike

2008-01-01

Poland and Germany have a long common border which leads to the necessity to cooperate and consult each other in the case of large-scale projects or infrastructure measures likely to cause negative transboundary effects on the environment. There are already binding provisions for transboundary EIA. In the area of the UN Economic Commission for Europe (UNECE), transboundary EIA is intended to be legally binding for the Member States by the Espoo Convention which was ratified by Germany 8.8.2002 and by Poland 12.6.1997. Due to corresponding directives, the same is applicable in the context of the European Union. In German legislation, this issue is regulated by Art. 8 of the Federal EIA Act in regard to transboundary participation of administration and by Art. 9a in respect of transboundary public participation. However, these EIA regulations on transboundary participation do not surpass a certain detail level, as they have to be applied between Germany and all neighbouring states. Therefore both countries decided to agree on more detailed provisions in particular regarding procedural questions. During the 12th German-Polish Environmental Council, Germany and Poland reached an agreement on 11.4.2006 in Neuhardenberg/Brandenburg an agreement upon the implementation of the Espoo Convention, the so called Neuhardenberg Agreement. This article assesses the agreement under consideration of already existing law and discusses major improvements and problems

Dental tourism from Switzerland to Germany.

Science.gov (United States)

Gheorghe, Raluca; Zürcher, Andrea; Filippi, Andreas

In recent years the topic of dental tourism has increasingly come into focus of dentists and patients. In the present study an attempt was made to find out, why patients from a restricted region travel to Germany for dental care. In five German dental clinics located in the border area between Switzerland and Germany, 272 women and 236 men ranging in age from 5 to 94 years, who had undergone at least one dental treatment in Germany, were questioned concerning the reasons for their visits. The interviews took place within a period of 6 months and relied on a questionnaire to collect data regarding sociodemographic features and patient behavior. In comparison to residents of Germany, patients residing in Switzerland took on considerably longer travel distances for the dental visit, in some cases more than 50km (9.7%). For patients residing in Switzerland the technical equipment of the practice was more important (pSwitzerland (95.6%) confirmed that dental treatments in Germany were cheaper and that additional family members also came to Germany for dental care (65.0%).

Radiotherapy in Northern Germany: Facts and figures about radiooncology in 6 states

International Nuclear Information System (INIS)

Brodersen, H.J.; Heilmann, H.P.

1996-01-01

Traditionally there was a close cooperation between the Roentgen Society of Northern Germany and the Society of 'Niedersachsen' and 'Sachsen-Anhalt'. Therefore, hospital departments and free standing office-type facilities in radiooncology from 6 states have put together a regional North German data-base. Detailed questionnaires were sent out in order to get data on heads of departments, professional staff, technical equipment, workload, diagnoses and training facilities. The collected data were distributed to all participating centers for confidential individual analysis. This paper reports the data collected. The survey 1995/96 had an unexpected return. Thirty-six from 38 centers in a region with 17.36 million inhabitants in 6 states (21.3% of Germany) took part. There were 73 megavolt machines and 31 afterloading facilities. Two hundred and forty physicians, 110 physicists, and 350 radiographers were working in radiooncology; and there were 852 hospital beds specifically assigned to radiooncology for the care of in-patients. In 1995, 32,000 patients were treated with 37,000 series, 570,000 treatment visits and 1,600,000 radiation fields. The average patient got 1.2 series, 18 treatment visits and 50 fields. Equipmentwise, an average department runs a mean of 2 megavolt machines and 1 afterloading facility. The corresponding data for 1 megavolt machine were 3.5 physicians, 1.6 physicists, 5 radiographers and 13 hospital beds. There was 1 machine for 240,000 inhabitants. The average workload of a megavolt machine was 439 patients a year with 513 series, 7,813 treatment visits and 21,845 radiation fields. A regional data-base for radiooncology is being described. It is demonstrated that it is possible to get detailed and current data by this method. It provides transparent data on equipment, personnel and workload in radiooncology. It should set an example for other regions to collect their data in the same fashion, and then compile all such data for the whole

Germany's lignite industry in 2012; Die deutsche Braunkohlenindustrie im Jahr 2012

Energy Technology Data Exchange (ETDEWEB)

Maassen, Uwe [Bundesverband Braunkohle, Statistik der Kohlenwirtschaft e.V., Koeln (Germany); Schiffer, Hans-Wilhelm [RWE Aktiengesellschaft, Essen (Germany). CEA-W Allgemeine Wirtschaftspolitik/Wissenschaft

2013-05-15

From 2011 to 2012, Germany's domestic lignite output edged up to 5.1% from 176.5 mill. t to 185.4 mill. t. This figure is equivalent to a net calorific value of 57.2 mill. tce. Of the total output, 166.3 mill. t, or some 90%, was used in utility power plants for the public supply, i.e. 5.7% more than in the previous year. In addition, 15.1 mill. t was input in the factories of the lignite-mining industry to make solid products, while 3.0 mill. t was used to generate electricity in mine-mouth power plants. Other sales of raw lignite and changes in stocks accounted for 1.0 mill. t. Lignite made a 25.7% contribution toward Germany's total power generation in 2012. In 2012, lignite had a 12.1% share in primary-energy consumption balance after mineral oil (33.1%), natural gas (21.6%) and hard coal (12.2%). Renewable resources cover 11.6%, while nuclear energy accounts for 8.0% and other energy sources for 1.4%. With output of 57.2 mill. tce, lignite held a share of 38.4% in Germany's primary-energy production of some 149 mill. tce in 2012. The contributions made by other energy carriers to primary-energy production in 2012 were as follows: 11.1 mill. tce hard coal, 13.3 mill. tce gas, 3.8 mill. tce mineral oil, 54.0 mill. tce renewables, and 9.5 mill. tce other energy sources. Of the total electricity amount that Germany produced in 2012, 25.7% was accounted for by lignite. This means that lignite led the ranking of the most important input energies for electricity generation in 2012, followed by renewables with 22.1%, hard coal with 19.1%, nuclear energy with 16.1% and gas with 11.3%. Other energy sources made a 5.7% contribution to total gross power generation. The most important ratios for the contributions made by the various lignite-mining areas to Germany's energy supply are shown. CO{sub 2} emissions from lignite rose 5.1% from 173.9 mill. t in 2011 to 182.8 mill. t in 2012. In the total period from 1990 to 2012, a decline of 159.4 mill. t, or

Poverty, health, and nutrition in Germany.

Science.gov (United States)

Helmert, U; Mielck, A; Shea, S

1997-01-01

To investigate the relation between poverty and several variables describing health and nutrition behavior in East Germany and West Germany. Data are from the third National Health Survey in West Germany and the first Health Survey for the new federal states of Germany (1991/92). Both health surveys included a self-administered questionnaire ascertaining sociodemographic variables, smoking history, nutritional behavior (using a food-frequency list), physical activity, and a medical examination comprising measurements of height, weight, blood pressure, and blood sampling for serum cholesterol determination. Participants included 4958 subjects in the West Survey and 2186 subjects in the East Survey aged 25-69 years, with a respective net response rate of 69.0% and 70.2%. Poverty was defined as a household equivalence income of 62.5% or less of the median income of the general population. The lowest income group (poverty or near poverty) comprised 11.6% of East German versus 15.9% of West German males and 14.8% of East German versus 19.3% of West German females. For most but not all health and nutrition parameters, less favorable results were obtained for subjects with an equivalence income below or near poverty. The most striking poverty-related differences regarding cardiovascular disease risk factors were found for lack of regular exercise for both genders and obesity in females. No poverty-related differences were found for the prevalence of hypercholesterolemia, despite a much higher prevalence of obesity in persons with an income below the poverty line. Current nutritional behavior and changes in nutritional behavior during the last three years was strongly related to income status, with a more unhealthy status for low-income population groups in both East and West Germany. In Germany, poverty has strong effects on individual health status and nutritional behavior. Because of rising unemployment rates and reductions in social security payments for low

1 CFR 8.6 - Forms of publication.

Science.gov (United States)

2010-01-01

... 1 General Provisions 1 2010-01-01 2010-01-01 false Forms of publication. 8.6 Section 8.6 General... FEDERAL REGULATIONS § 8.6 Forms of publication. (a) Under section 1506 of title 44, United States Code, the Administrative Committee authorizes publication of the Code of Federal Regulations in the...

Smoking restrictions and hospitalization for acute coronary events in Germany.

Science.gov (United States)

Sargent, James D; Demidenko, Eugene; Malenka, David J; Li, Zhongze; Gohlke, Helmut; Hanewinkel, Reiner

2012-03-01

To study the effects of smoking restrictions in Germany on coronary syndromes and their associated costs. All German states implemented laws partially restricting smoking in the public and hospitality sectors between August 2007 and July 2008. We conducted a before-and-after study to examine trends for the hospitalization rate for angina pectoris and acute myocardial infarction (AMI) for an insurance cohort of 3,700,384 individuals 30 years and older. Outcome measures were hospitalization rates for coronary syndromes, and hospitalization costs. Mean age of the cohort was 56 years, and two-thirds were female. Some 2.2 and 1.1% persons were hospitalized for angina pectoris and AMI, respectively, during the study period from January 2004 through December 2008. Law implementation was associated with a 13.3% (95% confidence interval 8.2, 18.4) decline in angina pectoris and an 8.6% (5.0, 12.2) decline in AMI after 1 year. Hospitalization costs also decreased significantly for the two conditions-9.6% (2.5, 16.6) for angina pectoris and 20.1% (16.0, 24.2) for AMI at 1 year following law implementation. Assuming the law caused the observed declines, it prevented 1,880 hospitalizations and saved 7.7 million Euros in costs for this cohort during the year following law implementation. Partial smoking restrictions in Germany were followed by reductions in hospitalization for angina pectoris and AMI, declines that continued through 1 year following these laws and resulted in substantial cost savings. Strengthening the laws could further reduce morbidity and costs from acute coronary syndromes in Germany.

Smoking restrictions and hospitalization for acute coronary events in Germany

Science.gov (United States)

Sargent, James D.; Demidenko, Eugene; Malenka, David J.; Li, Zhongze; Gohlke, Helmut

2013-01-01

Aims To study the effects of smoking restrictions in Germany on coronary syndromes and their associated costs. Methods and results All German states implemented laws partially restricting smoking in the public and hospitality sectors between August 2007 and July 2008. We conducted a before-and-after study to examine trends for the hospitalization rate for angina pectoris and acute myocardial infarction (AMI) for an insurance cohort of 3,700,384 individuals 30 years and older. Outcome measures were hospitalization rates for coronary syndromes, and hospitalization costs. Mean age of the cohort was 56 years, and two-thirds were female. Some 2.2 and 1.1% persons were hospitalized for angina pectoris and AMI, respectively, during the study period from January 2004 through December 2008. Law implementation was associated with a 13.3% (95% confidence interval 8.2, 18.4) decline in angina pectoris and an 8.6% (5.0, 12.2) decline in AMI after 1 year. Hospitalization costs also decreased significantly for the two conditions—9.6% (2.5, 16.6) for angina pectoris and 20.1% (16.0, 24.2) for AMI at 1 year following law implementation. Assuming the law caused the observed declines, it prevented 1,880 hospitalizations and saved 7.7 million Euros in costs for this cohort during the year following law implementation. Conclusions Partial smoking restrictions in Germany were followed by reductions in hospitalization for angina pectoris and AMI, declines that continued through 1 year following these laws and resulted in substantial cost savings. Strengthening the laws could further reduce morbidity and costs from acute coronary syndromes in Germany. PMID:22350716

8 CFR 245.6 - Interview.

Science.gov (United States)

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Interview. 245.6 Section 245.6 Aliens and... ADMITTED FOR PERMANENT RESIDENCE § 245.6 Interview. Each applicant for adjustment of status under this part shall be interviewed by an immigration officer. This interview may be waived in the case of a child...

8 CFR 1245.6 - Interview.

Science.gov (United States)

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Interview. 1245.6 Section 1245.6 Aliens and... OF STATUS TO THAT OF PERSON ADMITTED FOR PERMANENT RESIDENCE § 1245.6 Interview. Each applicant for adjustment of status under this part shall be interviewed by an immigration officer. This interview may be...

Seminar on Biogas in France and in Germany: Regulatory framework, potentials and challenges

International Nuclear Information System (INIS)

Abadie, Pierre-Marie; Boettcher, Katharina; Stolpp, Sebastian; Vincent, Eric; Chapron, Thibaut; Schuette, Andreas; Paquin, Laurent; Ingremeau, Claire; Moeller, Kurt; Trommler, Marcus; Denysenko, Velina; Bosso, Valerie

2014-01-01

The French-German office for Renewable energies (OFAEnR) organised a Seminar on biogas in France and Germany. In the framework of this French-German exchange of experience, about 120 participants exchanged views on the legal framework, the characteristics of this industry, and the opportunities and technical challenges of biogas use in both countries. Differences and similarities were noticed in both countries, for instance regarding the use of energy cultures and digestates. This document brings together the available presentations (slides) made during this event: 1 - The French biogas in the perspective of 2020 (Pierre-Marie Abadie); 2 - Biogas Opportunities in Germany - Status January 2014 (Katharina Boettcher); 3 - Biogas market in Germany (Sebastian Stolpp); 4 - Biogas in France and Germany, Current status and development outlooks in France (Eric Vincent); 5 - Biogas use in France and Germany - a comparison (Thibaut Chapron); 6 - Alternatives to the use of maize in biogas plants - Current research results from Germany (Andreas Schuette); 7 - Inter-crops in France: analysis of the potentials (Laurent Paquin); 8 - Digestates management in France, legislative and technical advances (Claire Ingremeau); 9 - The management of digestates in Germany: Fertilizer application and status of the art (Kurt Moeller); 10 - Status quo of Biomethane in Germany - Development, Technology and Costs (Marcus Trommler); 11 - GrDF's views and actions on biogas. Biomethane injection in France: state-of-the-art and first status (Valerie Bosso)

Passive surveillance of Leptospira infection in swine in Germany.

Science.gov (United States)

Strutzberg-Minder, Katrin; Tschentscher, Astrid; Beyerbach, Martin; Homuth, Matthias; Kreienbrock, Lothar

2018-01-01

As no current data are available on the prevalence of leptospiral infection in swine in Germany, we analysed laboratory data from diagnostic examinations carried out on samples from swine all over Germany from January 2011 to September 2016. A total of 29,829 swine sera were tested by microscopic agglutination test (MAT) for antibodies against strains of eleven Leptospira serovars. Overall, 20.2% (6025) of the total sample collection tested positive for leptospiral infection. Seropositivity ranged between 16.3% (964) in 2011 and 30.9% (941) in 2016 (January to September only). Of all samples, 11.6% (57.3% of the positives) reacted with only one Leptospira serovar, and only 8.6% (42.7% of the positives) reacted simultaneously with two or more serovars. The most frequently detected serovar was Bratislava, which was found in 11.6% (3448) of all samples, followed by the serovars Australis in 7.3% (2185), Icterohaemorrhagiae in 4.0% (1191), Copenhageni in 4.0% (1182), Autumnalis in 3.7% (1054), Canicola in 2.0% (585), and Pomona in 1.2% (368). Modelling shows that both the year and the reason for testing at the laboratory had statistically strong effects on the test results; however, no interactions were determined between those factors. The results support the suggestion that the seropositivities found may be considered to indicate the state of leptospiral infections in the German swine population. Although data from passive surveillance are prone to selection bias, stratified analysis by initial reason for examination and analyses by model approaches may correct for biases. A prevalence of about 20% for a leptospiral infection is most probable for sows with reproductive problems in Germany, with an increasing trend. Swine in Germany are probably a reservoir host for serovar Bratislava, but in contrast to other studies not for Pomona and Tarassovi.

Speech at German Council on Foreign Relations, 8 October 2010, Berlin, Germany

International Nuclear Information System (INIS)

Amano, Yukiya

2010-01-01

It is a great honour for me to speak at the German Council for International Relations. Germany is a strong believer in multilateral diplomacy and has always been a staunch supporter of the International Atomic Energy Agency. It is an experienced user of nuclear science and technology for peaceful purposes and participates actively in the Agency's programmes. Germany is also a generous provider of international development aid, including through the IAEA's technical cooperation programme, which makes nuclear technologies available to developing countries. And Germany is committed to the goal of a world free of all nuclear weapons. Since taking office, I have been trying to change the widespread perception of the Agency as simply the world's 'nuclear watchdog' because it does not do justice to our extensive activities in other areas, especially in nuclear energy, nuclear applications, and technical cooperation. In the half-century since it was established, the Agency has pursued two undamental goals: preventing the proliferation of nuclear weapons and helping to make nuclear technologies available for peaceful applications. would like to focus on three main areas - nuclear power, nuclear sciences and applications, and nuclear non-proliferation - and say a few words about the management of the Agency.

Country report for Germany [Fast reactors in Germany

International Nuclear Information System (INIS)

Knebel, J.

2007-01-01

Full text: The primary energy consumption in Germany in 2005 was about 492.6 MtSKE in total. The distribution on the main energy sources is: mineral oil: 36.4%, natural gas 22.4%, black coal 13.5%, brown coal 11.4%, nuclear energy 12.6%, water and wind 1.2%, others 2.5%. The net electricity production in Germany in 2005 was about 495.9 billion kWh. The distribution is: nuclear energy 32%, lignite coal 28.9%, black coal 23.1%, oil 0.2%, natural gas 9.1%, water 4.7%, others (being biomass, photovoltaics, wind) 2.0%. In 2005, 18 nuclear power plants were in operation in Germany. In May 2005 the KWO Obrigheim was closed due to the new Atomic law which fixes the phase out of nuclear power production. The net installed nuclear power was 20.7GWel, the net nuclear electricity production was 163TWh, the time availability was 88%. Nuclear makes up for about 50% of the base-load electricity production in Germany. In absolute numbers, Germany is number 5 in nuclear electricity production. Among the top ten nuclear power plants world-wide, in 2005 there were 7 German plants including the plant with the highest amount of electricity produced, being NPP Brokdorf with 1440MWel and 11.98TWhel. The net electricity output of the nuclear power plants is constantly increasing due to power upgrading and higher time availabilities. As for the renewable energies, there is no significant absolute increase except for wind. About 50% of the government support for renewable energies from the Environmental Ministry goes to photovoltaics. The Helmholtz-Gemeinschaft (HGF), summarising 15 national research centres, 24.000 employees and a yearly budget of about 2,1 billion Euro is the largest research organisation in Germany. The HGF identifies and works on complex and urgent questions of society, science and economy, especially concentrating on systems of high complexity. There are six research areas, being energy, earth and environment, health, key technologies, structure of matter, traffic and

Conference on participatory wind energy in France and in Germany

International Nuclear Information System (INIS)

Vohrer, Philipp; Poize, Noemie; Hanus, Dominik; Hallmann, Dieter; Jourdain, Pierre; Ruehl, Martin; Bessiere, Patrick; Guyonnet-Duperat, Philippe; Foerster, Maelle; Partetzke, Matthias; Rumolino, Claudio

2014-01-01

The French-German office for Renewable energies (OFAEnR) organised a conference on participatory wind energy in France and in Germany. In the framework of this French-German exchange of experience, about 150 participants exchanged views on the role and involvement of citizens in wind energy projects and raised the question of the prerequisite to the construction of a participatory wind farm. In this framework, the different participatory models existing in both countries were analysed, in particular with regard to their respective advantages and drawbacks and to a legal framework which remains to be defined. Four projects, 2 in France and 2 in Germany, were presented as examples. The call for proposals model was presented and debated as well as the question of the project success, and of its financing and profitability. This document brings together the available presentations (slides) made during this event: 1 - Community wind farms in Germany: status quo and forecast (Philipp Vohrer); 2 - Participatory projects in France: which legal solutions, which prospects for development? (Noemie Poize); 3 - Citizen owned wind farms and their legal forms in Germany: Advantages and challenges of the different schemes (Dominik Hanus); 4 - Make wind power profitable: Citizen participation in Germany and France/Make the energy transition together. The energy co-operative participation as a model in Germany (Dieter Hallmann); 5 - Power to the people - A new model for French wind energy. Beganne community-owned wind farm (Pierre Jourdain); 6 - Making wind power profitable: civic participation in Germany and France: German utility companies rely on wind power. Direct civic participation in the municipal utility company - democratization of the turnaround in energy policy (Martin Ruehl); 7 - French municipalities get involved: calls for projects (Patrick Bessiere); 8 - Crowd-funding - French regulatory framework (Philippe Guyonnet-Duperat, Maelle Foerster); 9 - Making wind energy

6 CFR 5.8 - Business information.

Science.gov (United States)

2010-01-01

... 6 Domestic Security 1 2010-01-01 2010-01-01 false Business information. 5.8 Section 5.8 Domestic... Freedom of Information Act § 5.8 Business information. (a) In general. Business information obtained by... this section. (b) Definitions. For purposes of this section: (1) Business information means commercial...

Eastern Germany Ahead in Employment of Women

OpenAIRE

Elke Holst; Anna Wieber

2014-01-01

Almost a quarter of a century after the fall of the Wall, there are still more women in employment in eastern Germany than in the west. Although the disparity is marginal now, the two regions started from dramatically different levels. In 1991, immediately after reunification, the employment rate for women in western Germany was 54.6 percent, but since then it has increased year on year, reaching 67.5 percent in 2012. In eastern Germany, female employment initially plummeted after the fall of...

[Attitudes towards age-related rationing of medical supply: results of a cross-national analysis in Germany and Austria].

Science.gov (United States)

Esslinger, Adelheid Susanne; Meier, Florian; Roller-Wirnsberger, Regina E; Heppner, Hans Jürgen

2011-07-01

Expenditure on health-care is increasing over the last years and the demographic shift leads to more elderly patients in the health-care system. Debates about the financial situation and solution about this topic are common. Direct, as well as hidden, rationing is verified by experts. This article discusses the concept of age-dependent prioritization and rationing of health-care expenditures in a cross-national setting. With a standardised questionnaire geriatric physicians in Germany and Austria were asked about their attitude and experience with health-care expenditures in elderly patients. Dimension of medical staff, organising institution and financial resources were also evaluated. The sample was tested with t-test, Mann-Whitney-U-test and explorative factor analysis. All the data were calculated with PASW 17 Statistics(®). From 419 standardised questionnaires 288 forms (60%, Germany: 123, Austria: 165) were evaluated. Differences were shown in patient-age (Germany: 80.4 y, Austria: 71.8 y), carrying capacity (Germany: 74.8, Austria: 110.8) and in medical staff as physicians (Germany: 6.8, Austria: 12.7) and nursing (Germany: 32.2, Austria: 84.3). In infrastructural basic services and normative focusing there was only marginal discrepancy, the public/ecclesiastical organising institution was 71% in both countries. Related to the different financial systems, there was less cost pressure in taking care of elderly patients in Austria. Age-dependent rationing was approved, but there was also a clear endorsement for making resources available for elderly patients in future. The discussion about rationing of health-care expenditures will still go on and therefore the impact of ageism has to be evaluated in further studies.

Prevalence of pain medication prescriptions in France, Germany, and the UK - a cross-sectional study including 4,270,142 patients.

Science.gov (United States)

Jacob, Louis; Kostev, Karel

2018-01-01

The goal of the present study was to analyze the prevalence of pain medication prescriptions in general practices in France, Germany, and the UK. This study included all patients aged ≥18 years followed in 2016 in general practitioner practices in France, Germany and the UK. The primary outcome was the prevalence of patients receiving prescriptions for pain medications in France, Germany, and the UK in 2016. The following drugs were included in the analysis: anti-inflammatory and antirheumatic products, non-steroids and analgesics including opioids, antimigraine preparations, and other analgesics and antipyretics. Demographic variables included age and gender. This study included 4,270,142 patients. The prevalences of pain medication prescriptions were 57.3% in France, 29.6% in Germany, and 21.7% in the UK. Although this prevalence generally remained consistent between age groups in France (54.3%-60.3%), it increased with age in Germany (18-30 years: 23.8%; >70 years: 35.8%) and in the UK (18-30 years: 9.3%; >70 years: 43.8%). Finally, the prevalence of pain medication prescriptions was higher in women than in men in all three countries. Paracetamol was prescribed to 82.3% and 60.1% of patients receiving pain medication in France and the UK, respectively, whereas ibuprofen was prescribed to 46.5% of individuals in Germany. The prevalence of pain medication prescriptions was higher in France than in Germany and the UK. Further research is needed to gain a better understanding of the differences in the prescription patterns between these three European countries.

The effects of sulfur intercalation on the optical properties of artificial 'hackmanite', Na8[Al6Si6O24]Cl1.8S0.1; 'sulfosodalite', Na8[Al6Si6O24]S; and natural tugtupite, Na8

DEFF Research Database (Denmark)

Warner, Terence Edwin; Hutzen Andersen, Jan

2012-01-01

.8S0.1 destroys the tenebrescence and induces a permanently pale blue and, at higher temperature, a pale green coloration. The effect on Na8[Al6Si6O24]S induced similar colorations but of a deeper hue. Annealing tugtupite, Na8[Be2Al2Si8O24](Cl,S)2-x under a sulfur atmosphere over the range 600-700 °C......, destroyed the tenebrescence and resulted in a colourless tugtupite; but did not effect the photoluminescence. This suggests that the chemical species responsible for the tenebrescence in tugtupite is unlikely to be the same as that for the luminescence....

Tris(dibenzoylmethanido-κ2O,O′[(6S,8S-(+-7,7-dimethyl-3-(2-pyridyl-5,6,7,8-tetrahydro-6,8-methanoisoquinoline-κ2N,N′]gadolinium(III

Directory of Open Access Journals (Sweden)

Xi-Li Li

2009-09-01

Full Text Available In the title compound, [Gd(C15H11O23(C17H18N2], the GdIII atom is coordinated by six O atoms from three β-diketonate ligands and two N atoms from a chiral ligand LS,S-(+-7,7-dimethyl-3-(2-pyridyl-5,6,7,8-tetrahydro-6,8-methanoisoquinoline, in a coordination geometry best described as distorted square-antiprismatic.

8 CFR 217.6 - Carrier agreements.

Science.gov (United States)

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Carrier agreements. 217.6 Section 217.6 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS VISA WAIVER PROGRAM § 217... may notify a carrier of the existence of a basis for termination of a carrier agreement under this...

6 CFR 25.8 - Government contractor Defense.

Science.gov (United States)

2010-01-01

... 6 Domestic Security 1 2010-01-01 2010-01-01 false Government contractor Defense. 25.8 Section 25.8...-TERRORISM BY FOSTERING EFFECTIVE TECHNOLOGIES § 25.8 Government contractor Defense. (a) Criteria for... applicability of the government contractor defense. In determining whether to issue such Certification, the...

24 CFR 8.6 - Communications.

Science.gov (United States)

2010-04-01

... URBAN DEVELOPMENT General Provisions § 8.6 Communications. (a) The recipient shall take appropriate... required to provide individually prescribed devices, readers for personal use or study, or other devices of..., telecommunication devices for deaf persons (TDD's) or equally effective communication systems shall be used. (b) The...

Conference on hydrogen-energy in France and Germany

International Nuclear Information System (INIS)

Bodineau, Luc; Menzen, Georg; Arnold, Peter Erich; Mauberger, Pascal; Roentzsch, Lars; Poggi, Philippe; Gervais, Thierry; Schneider, Guenther; Colomar, David; Buenger, Ulrich; Nieder, Babette; Zimmer, Rene; Jeanne, Fabrice; Le Grand, Jean-Francois

2014-01-01

The French-German office for Renewable energies (OFAEnR) organised a conference on hydrogen-energy in France and Germany. In the framework of this French-German exchange of experience, about 200 participants exchanged views on the different perspectives for use of hydrogen, in particular in transportation and energy storage applications. The technical production, transport and storage means were addressed too, as well as the technological models and the conditions for a large-scale industrial deployment. The economic prospects of hydrogen-energy in tomorrow's energy mix were also considered during the conference. This document brings together the available presentations (slides) made during this event: 1 - Hydrogen energy and Fuel Cells in France Today, and prospective (Luc Bodineau); 2 - The situation of energy Policy in Germany and the challenges for the Hydrogen Technology (Georg Menzen); 3 - Unlocking the Hydrogen Potential for Transport and Industry (Peter Erich Arnold); 4 - Hydrogen, a new energy for our planet - Hydrogen storage possibilities: example of solid storage (Pascal Mauberger); 5 - Innovative Materials and Manufacturing Technologies for H 2 Production and H 2 Storage (Lars Roentzsch); 6 - Scientific development and industrial strategy: experience feedback from the Myrte platform and energy transition-related perspectives (Philippe Poggi, Thierry Gervais); 7 - 'Power to Gas' - Important partner for renewables with big impact potential (Guenther Schneider) 8 - Developing a Hydrogen Infrastructure for Transport in France and Germany - A Comparison (David Colomar, Ulrich Buenger); 9 - H 2 and Fuel-Cells as Key Technologies for the Transition to Renewable energies - The example of Herten (Babette Nieder); 10 - Social acceptance of hydrogen mobility in Germany (Rene Zimmer); 11 - Hydrogen - A development opportunity for regions? (Fabrice Jeanne)

40 Years MAGLEV Vehicles in Germany

OpenAIRE

Meisinger, Reinhold; Guangwei, Shu

2011-01-01

On May 6th 1971 the worldwide first MAGLEV vehicle was presented by Messerschmitt-Bölkow-Blohm (MBB) in Ottobrunn near Munich, Germany. Till the year 2000 different test and application MAGLEV vehicles followed, but no commercial use in Germany. Since December 31st 2002 the Shang-hai MAGLEV Transportation System is successfully in operation, as the worldwide first and only one commercial used MAGLEV line. The paper in honour of Prof. Dr.-Ing. Eveline Gottzein for her 80th birthday contains in...

6 CFR 13.8 - Service of Complaint.

Science.gov (United States)

2010-01-01

... 6 Domestic Security 1 2010-01-01 2010-01-01 false Service of Complaint. 13.8 Section 13.8 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY PROGRAM FRAUD CIVIL REMEDIES § 13.8 Service of Complaint. (a) Service of a Complaint must be Made by certified or registered mail or by...

Siegenberg Germany Gunnery Range, Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A-F

Science.gov (United States)

1971-10-28

1 OP1470-- WET BULS TEMPERATURE DEPRESSIO -4 F’ OA" , 0F 1-2 3- 5-6 7-8 9. 10 11- 12 13- 14 1.- 16 17. : 19 20 21- - --s , 5 . D - 88/ 87 log 2 86...PSYCHROMETRIC SUMMARY AIR AEATE E SERVICE/AC 34199 SIEGEN5uRG GERMANY GUNNERY RAhGE e87C Sp’ AA :- E 1 - wET eULB TE-PERATuRE DEPRESSIO -- F- C - 3 5. 6

Job satisfaction of radiologists in Germany. Status quo

International Nuclear Information System (INIS)

Beitzel, K.I.; Grosse, C.; Reiser, M.; Ertl-Wagner, B.; Ertl, L.

2011-01-01

Purpose: The aim of this study was to identify and evaluate the work-related satisfaction of radiologists and its influencing factors in Germany. Materials and Methods: For this purpose an invitational letter for an online opinion survey was sent to all member physicians of the Deutsche Roentgengesellschaft in 2008. 1200 questionnaires were completed (response rate 21 %) and evaluated statistically. Results: 81.7 % of radiologists declared themselves as being 'very' or 'rather satisfied'. The level of satisfaction was largely independent of age, gender, status, salary or family status. It increased over the last 5 years for 37.5 % of participants and decreased for 24.8 %. Nevertheless, 72 % of respondents indicated that they would not choose to specialize in radiology again. The main reason given was the workload. 65.6 % deemed it to be 'considerably' or 'rather too high'. Concomitantly, more than 70 % of respondents indicated that the workload had increased 'a lot' or 'rather'. Further reasons for not wanting to select the radiological profession again were 'unfavorable working hours' and 'unsatisfactory career perspectives'. Conclusion: The job satisfaction of radiologists in Germany is generally very high in spite of the perception of an extensive and frequently increasing workload. The high workload was the dominant factor against a renewed selection of the field of radiology. These data have to be interpreted in light of the current lack of residents and trained radiologists in Germany to counteract the trend toward emigration. (orig.)

Biogas conference on direct selling and financing in France and in Germany

International Nuclear Information System (INIS)

Furois, Timothee; Vollmer, Carla; Schlienger, Marc; Delagrandanne, Julien; Schwill, Jochen; Trommler, Marcus; Barchmann, Tino; Dotzauer, Martin; Durot, Alexandre; Ricordeau, Damien; Schuenemann-Plag, Peter; Wehner, Gustav; Wagner, Robert; Mestrel, Marc

2016-01-01

The French-German office for Renewable energies (OFAEnR) organised a conference on the regulatory context, direct selling and financing of methanation plants in France and in Germany. In the framework of this French-German exchange of experience, about 60 participants debated the following topics: direct selling impact on biogas industry, key-steps of methanation development in Germany, experience feedback of direct electricity selling and optimization of the production, banks experience feedback in methanation financing. This document brings together the available presentations (slides) made during this event: 1 - French support schemes for biogas (Timothee Furois); 2 - Development of the framework for biogas plants within the Renewable energy Sources Act from 2000 until 2015 (Carla Vollmer); 3 - Direct selling: challenges and opportunities (Marc Schlienger); 4 - The rules of the aggregator and electricity market (Julien Delagrandanne); 5 - Feed in Premium (FiP) with Biogas Power Plants, experiences in Germany (Jochen Schwill); 6 - Flexibilisation of biogas production - Impulses from EEG -legislation (Marcus Trommler); 7 - Bank approach in the direct selling approach (Alexandre Durot); 8 - Biogas Financing - Correlation between Return and Project Financing (Damien Ricordeau); 9 - Comparative economic analysis of various types of biogas plant Profitability of small and medium biogas plants on the basis of slurry and maize silage in Germany (Peter Schuenemann-Plag); 10 - experience feedback on important financing leviers (Gustav Wehner); 11 - Analysis of the different ways of methanation facilities financing (Robert Wagner); 12- The development of biogas project without recourse to purchase prices in France and Germany (Marc Mestrel)

Range 8C Rehabilitation Demonstration Project, Hohenfels Training Area, Germany: Final report

International Nuclear Information System (INIS)

Zellmer, S.D.; Hinchman, R.R.; Johnson, D.O.; Brent, J.J.

1991-11-01

More than 30 years of intensive and continual tactical training has caused extensive environmental damage at the US Army Hohenfels Training Area in Germany. The Range 8C Rehabilitation Demonstration Project, followed by a three-year monitoring effort, was conducted to develop and evaluate the environmental and economic effectiveness of seven revegetation and four erosion control prescriptions implemented at a 16-ha site. The point-intercept method was used to measure the types and amounts of vegetation established and the changes in the vegetative community during three years of military use on the seven areas treated with revegetation prescriptions. Field observations were made to determine the suitability and durability of four types of erosion control structures. Soil fertility and a source of seed appeared to be the most limiting factors in establishing vegetation, while seedbed preparation had only a minor influence. Grasses appeared to be more resistant to vehicle traffic than did other types of vegetation. Because grassed waterways were used as roads by military vehicles and a system of graded terraces was expensive, these erosion control prescriptions were unsuitable and uneconomical for use on training areas. Low-cost riprap waterbars and porous check dams slowed the velocity of runoff, trapped sediments, and were durable. Recommendations were formulated to improve the environmental and economic effectiveness of future rehabilitation efforts on tactical training areas

Report on nuclear power plant instrumentation and control in Germany

International Nuclear Information System (INIS)

Bastl, W.

1992-01-01

The paper describes the status of the NPP control and instrumentation in Germany. The general technology underlying most aspects of NPP C and I in Germany has not altered since the last progress report although there has been many improvements in detail. Since the beginning of 1990 the GRS carried out the safety investigations of NPPs in East Germany. The USSR as the vendor of the plants and France were also involved in the project. The following fields are briefly described: Status of nuclear power in Germany; training simulators; backfitting of computers and information systems; operator support/new control rooms. (author). 6 refs, 1 tab

Wind power report Germany 2014

International Nuclear Information System (INIS)

Rohrig, Kurt

2015-01-01

Record year 2014. In Germany, the expansion figures attained were so high on land and at sea that the overall new installation figure of 5,188 MW surpassed the previous maximum (from 2002) by more than 60%. With an overall capacity of 39,259 MW, for the first time, wind energy in Germany covers 9.7% of gross power consumption. On the global scale a capacity of more than 51,000 MW has been added - another record high for wind energy installations. Power mix. At 161 TWh, renewable energies in Germany covered 27.8% of gross power consumption and provided for the first time more energy than any other energy source. Coming into force of the new REA in August 2014, modified support schemes caused the expansion of biogas plants and large-scale PV installations to falter. The record expansion seen for wind energy can be interpreted as a pull-forward effect due to the tender procedures coming into force in 2017. Grid integration. Loss of production caused by feed-in management measures rose by 44% to 555 GWh as compared to 2012. Wind turbines were affected in 87% of cases but the impact on PV installations is increasing. Power generation must be more flexible and grids expanded to limit loss of production. Of the 23 expansion projects (1,887 km) in the Electricity Grid Expansion Act, just a quarter of them had been realized by the end of 2014 (463 km). In the preliminary analysis results for the 2014 grid development plan, the extent of grid upgrading and conversion was 3050 km. Offshore, the HelWin 1 grid link with a capacity of 580 MW went online. SylWin 1 and BorWin 2, with a total capacity of 1660 MW, are currently being tested in a trial. In the preliminary analysis results for the 2014 offshore grid development plan, grid connections having an overall capacity of 10.3 GW are planned. Onshore. 2014 saw a total of 44 different turbine types installed in Germany. For the first time, virtually the same number of turbines were added in the 3-4 MW class, as in the 2-3 MW

Biomass in Germany

International Nuclear Information System (INIS)

Chapron, Thibaut

2014-01-01

This document provides, first, an overview of biomass industry in Germany: energy consumption and renewable energy production, the French and German electricity mix, the 2003-2013 evolution of renewable electricity production and the 2020 forecasts, the biomass power plants, plantations, biofuels production and consumption in Germany. Then, the legal framework of biofuels development in Germany is addressed (financial incentives, tariffs, direct electricity selling). Next, a focus is made on biogas production both in France and in Germany (facilities, resources). Finally, the French-German cooperation in the biomass industry and the research actors are presented

75 FR 12804 - Withdrawal of Regulatory Guide 8.6

Science.gov (United States)

2010-03-17

... ``Regulatory Guides'' in the NRC's Electronic Reading Room at http://www.nrc.gov/reading-rm/doc-collections... NUCLEAR REGULATORY COMMISSION [NRC-2010-0103] Withdrawal of Regulatory Guide 8.6 AGENCY: Nuclear Regulatory Commission. ACTION: Withdrawal of Regulatory Guide 8.6, ``Standard Test Procedure for Geiger-M...

F6H8 as an Intraoperative Tool and F6H8/Silicone Oil as a Postoperative Tamponade in Inferior Retinal Detachment with Inferior PVR

Directory of Open Access Journals (Sweden)

Gian Marco Tosi

2014-01-01

Full Text Available Purpose. To evaluate the effectiveness and safety of perfluorohexyloctane (F6H8 for intraoperative flattening of the retina and of F6H8/silicone oil (SO 1000 cSt as a postoperative tamponade for inferior retinal detachment with inferior proliferative vitreoretinopathy. Methods. This is a retrospective review of 22 patients who underwent pars plana vitrectomy using F6H8 as an intraoperative tool to flatten the retina. At the end of the surgery a direct partial exchange between F6H8 and SO 1000 cSt was performed, tamponing the eye with different ratios of F6H8/SO (70/30, 60/40, 50/50, 40/30, and 30/70. Anatomical and functional results and complications were evaluated over the follow-up period (mean 22.63 months. Results. F6H8 was efficacious for intraoperative flattening of the retina. Twenty-one of the 22 patients achieved a complete retinal reattachment. Postoperative visual acuity (VA ranged from light perception to 20/70, with 72% of patients obtaining VA better than 20/400. No emulsification/inflammation was observed whatever the ratio of F6H8/SO used. With higher ratios of F6H8/SO (70/30 and 60/40 cloudiness of the tamponade was observed. A transparent mixture was present with all the other ratios. Conclusions. The surgical technique adopted is very simple and safe. The optimal F6H8/SO ratio seems to be between 50/50 and 30/70.

8 CFR 1235.6 - Referral to immigration judge.

Science.gov (United States)

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Referral to immigration judge. 1235.6 Section 1235.6 Aliens and Nationality EXECUTIVE OFFICE FOR IMMIGRATION REVIEW, DEPARTMENT OF JUSTICE IMMIGRATION REGULATIONS INSPECTION OF PERSONS APPLYING FOR ADMISSION § 1235.6 Referral to immigration judge...

8TH International Laser Physics Workshop Lphys󈨧 Budapest, July 2-6, 1999, Program

Science.gov (United States)

1999-07-05

Gerhard J. MUller (Germany) Rudolf Steiner (Germany) Symposium Status and Future Directions of High-Power Laser Installations Co-Chairs: See Leang...Sciences, Kazan. Russia I.A. Shcherbakov General Physics Institute. Russian Academy of Sciences. Moscow, Russia R. Steiner Institute of Laser Technologies...14.50-15.15 R. Steiner , A. Pohl, A. Bentele, T. Meier (Ulm, Germany) Laser Doppler sensor for laser assisted injection 30 SEMINAR 5 --- LASER METHODS IN

Weimar Germany

DEFF Research Database (Denmark)

Reckendrees, Alfred

The Weimar Republic is analysed within the framework of limited and open access orders. Germany had developed into a mature limited access order before World War I, with rule of law and open economic access but only limited access to politics. After the war, Germany developed toward an open access...... order; this process was, however, not sustainable. Two interpretations are discussed, which both pose a challenge to the limited access-open access framework: (1.) Weimar Germany was the first open access order that failed; (2.) sufficiency conditions of the sustainability of open access are not yet...

8 CFR 235.6 - Referral to immigration judge.

Science.gov (United States)

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Referral to immigration judge. 235.6 Section 235.6 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS INSPECTION OF PERSONS APPLYING FOR ADMISSION § 235.6 Referral to immigration judge. (a) Notice—(1) Referral by Form I...

Heat capacities and phase analysis of the superconductive compounds Mosub(6+y0) Se8 and Gdsub(x0) Mosub(6+y0) Se8

International Nuclear Information System (INIS)

Nerz, K.P.

1979-02-01

High precision heat capacity measurements were performed on a high quality sample of Mo 6 Se 8 . The values obtained for the Sommerfeld-constant γ, density of states N(Esub(F)) and entropy S 2 (Tsub(c)) of the electronic system are a factor 1.5 to 2 larger than have been published earlier by other groups. The differences are attributed to the lower concentration of impurity phases in our sample. Our sample of Mo 6 Se 8 shows a discontinuity in the electronic heat capacity at Tsub(c) with a relative height (Csub(es)-Csub(en))/Csub(en) which is a factor 1.6 larger compared to an ideal BCS-superconductor. The energy gap in the excitation spectrum of the superconductor Mo 6 Se 8 is a factor 1.4 wider than for an ideal BCS-superconductor in the observed temperature regime. Our data for the electronic heat capacity of the superconducting phase Mo 6 Se 8 are in good agreement with the calculated values corresponding to the 'strong coupling'-model of Padamsee et al. For the characteristic quantity of the electron-phonon interaction, lambda, a value of 0.8 was calculated. All these results support the conclusions that Mo 6 Se 8 behaves like a superconductor with a strong electron-phonon interaction. In addition heat capacity measurements have been made for samples of the ternary Chevrel-phase compounds 'Gdsub(x 0 )Mosub(6+y 0 )Se 8 ' which were prepared by a variety of methods. A quantitative analysis of impurity phases has been made from the heat capacity data. (orig.) [de

Synthesis, structure and electronic configuration of [Rh{sub 6}Te{sub 8}(PPh{sub 3}){sub 6}].4C{sub 6}H{sub 6}

Energy Technology Data Exchange (ETDEWEB)

Thiele, Guenther; Balmer, Markus [Marburg Univ. (Germany). Fachbereich Chemie; Dehnen, Stefanie [Marburg Univ. (Germany). Fachbereich Chemie and Wissenschaftliches Zentrum fuer Materialwissenschaften

2016-08-01

[Rh{sub 6}Te{sub 8}(PPh{sub 3}){sub 6}].4C{sub 6}H{sub 6}, the first compound with a molecular Chevrel-type [Rh{sub 6}Te{sub 8}] cluster core has been synthesized and structurally characterized. By means of quantum chemical calculation, the close relationship of its electronic configuration to that of the lighter homologue has been demonstrated. The different crystal solvent content prevents an isostructural crystallization.

Evaluation of technetium-99m-Mag3-clearance. A pilot study of industry for the standardization of software

International Nuclear Information System (INIS)

Stritzke, H.P.

1996-01-01

The manufacturers for gamma camera systems and their distribution organisations in Germany, ADAC, Elscint, Gaede, General Electric, Picker, Siemens, Sopha and Toshiba initiated in cooperation with the Central Association of the Electro and Electronic Industry (Zentralverband der Elektro-und Elektronikindustrie eV, ZVEl), a pilot study to test whether the clinical computer programs for the calculation of the Technetium-99m-Mag 3 Clearance according Bubeck deliver comparable results. For this purpose three dynamic scintigraphic renal studies were converted to interfile format and were sent to the firms at two occasions including blood sampling data and anonymousized patient information. The results were returned to the SAM GmbH System Analysen in der Medizin (Bad Oeynhausen) and analyzed. All of the eight participating firms except one calculated correct clearance values. The reason for the failure in one case turned out to be a bug in the computer program. This pilot study has demonstrated that it is possible to establish certain technical standards for the clinical software in nuclear medicine but also to detect and correct errors. (orig.) [de

The electronuclear program of the Federal Republic of Germany

International Nuclear Information System (INIS)

Mandel, Heinrich

1978-01-01

The preoccupation of the Federal Republic is to lessen its energy dependency on petroleum (now 52%) particularly by developing nuclear power which could in the year 2,000 meet 27% of its primary energy needs, equally with oil. At the end of 1977, West Germany had 6 industrial reactors operating representing a total power of 5,500 MW., 12 reactors under construction (of which 8 units of 1,300 MW.) for a total power of 13,000 MW., 9 reactors under investigation (11,300 MW.), and 2 reactors 2,700 M. whose construction had been postponed for political reasons. A centre for fuel reprocessing and waste storage is also being investigated [fr

Conference on offshore wind power in France and Germany

International Nuclear Information System (INIS)

Meyer, Ronny; Furois, Timothee; Nolte, Nico; Lanoe, Frederic; Lehmann-Matthaei, Bjoern; Ifflaender, Andree; Courcambeck, Alexandre; Giese, Norbert; Kavafyan, Philippe; Bjaert, Niels; Wagner, Andreas; Guillet, Jerome

2014-01-01

The French-German office for Renewable energies (OFAEnR) organised a conference on offshore wind power in France and Germany. In the framework of this French-German exchange of experience, about 120 participants exchanged views on the planning and authorisation procedures implemented in both countries and on the installation, connection to the grid and maintenance of offshore wind turbines. environmental impacts and usage conflicts linked with offshore wind farms exploitation were addressed as well. This document brings together the available presentations (slides) made during this event: 1 - Update: Offshore Wind In Germany (Ronny Meyer); 2 - Offshore wind development in France (Timothee Furois); 3 - The Licensing Procedure for Offshore Wind Farms in the German EEZ (Nico Nolte); 4 - Spatial Planning and Permitting in France: What leverage for more efficiency? (Frederic Lanoe); 5 - Results of 10 years environmental research on FINO-platforms (Bjoern Lehmann-Matthaei); 6 - Offshore Grid Connection - Status Quo and Overview (Andree Ifflaender); 7 - Grid connection of Offshore Wind in France: Situation, perspectives and recommendations (Alexandre Courcambeck); 8 - Controlling risks and warranting safety: Best practices for the installation, exploitation and maintenance of offshore wind turbines (Norbert Giese); 9 - Offshore wind Bremerhaven experience: An essential asset for the development of a complete Wind Offshore industry in France (Philippe Kavafyan); 10 - Standardizing and Cost Reduction -Lessons Learned from London Array (Niels Bjaert); 11 - Offshore Wind energy in Germany: System Benefits and Cost Reduction Potentials. Presentation of study results from prognos/fichtner and Fraunhofer-IWeS (Andreas Wagner); 12 - Offshore Wind energy financing - opportunities and risks (Jerome Guillet)

Conference on offshore wind energy in France and Germany: challenges of a promising segment

International Nuclear Information System (INIS)

Chrupek, Thierry; Falk, Thorsten; Hofmann, Stefanie; Gouverneur, Philippe; Le Visage, Christophe; Saint Martin, Gro de; Meyerjuergens, Tim; Dachicourt, Pierre-Georges; Hube, Wilfried

2008-01-01

The French-German office for Renewable energies (OFAEnR) organised a conference on the development of offshore wind energy in France and Germany. In the framework of this French-German exchange of experience, more than 100 participants exchanged views on offshore wind energy development, and on the conflicts of usage between fishermen and offshore wind farms. This document brings together the available presentations (slides) made during this event: 1 - Offshore wind energy development in France (Thierry Chrupek); 2 - Present day situation of offshore wind energy development and use in Germany (Thorsten Falk); 3 - Risks and profitability of offshore wind energy (Philippe Gouverneur); 4 - Sea and shore integrated management: what impacts for offshore wind energy? (Christophe Le Visage); 5 - Towards and offshore grid? (Gro de Saint Martin); 6 - Grid connection of offshore wind farms in Germany (Tim Meyerjuergens); 7 - Conflicts of usage between professional fishing and offshore wind farms (Pierre-Georges Dachicourt); 8 - Ecological evaluative research for the use of offshore wind energy - Advantages, projects and studies. Environmental follow-up of wind energy projects (Stefanie Hofmann); 9 - Alpha Ventus offshore test park: context, progress of the installation and next steps (Wilfried Hube)

4,8-bisallyl-2,6-dimethylnaphthalene-1,5-diyl diacetate

DEFF Research Database (Denmark)

Christensen, Jørn Bolstad; Sørensen, Jeanett N.; Schaumburg, Kjeld

2014-01-01

4,8-Diallyl-2,6-dimethylnaphthalene-1,5-diyl diacetate (1) which is a highly substituted naphthalene derivative has been synthesized in two steps starting from 2,6-dimethyl-1,5-naphthalenediol (3) using a modified Claisen-rearrangement.......4,8-Diallyl-2,6-dimethylnaphthalene-1,5-diyl diacetate (1) which is a highly substituted naphthalene derivative has been synthesized in two steps starting from 2,6-dimethyl-1,5-naphthalenediol (3) using a modified Claisen-rearrangement....

Blood Relatives: Language, Immigration, and Education of Ethnic Returnees in Germany and Japan

Science.gov (United States)

Ortloff, Debora Hinderliter; Frey, Christopher J.

2007-01-01

Since 1989, large numbers of "ethnic returnees" have settled in Germany and Japan. After the fall of the Berlin Wall in 1989, 2.8 million "Aussiedler," or ethnic German returnees, came to Germany from the former Soviet Union. In Japan, immigration reform driven by low-skill labor shortages induced nearly 300,000…

(4bS,8aS-1-Isopropyl-4b,8,8-trimethyl-4b,5,6,7,8,8a,9,10-octahydrophenanthren-2-yl acetate

Directory of Open Access Journals (Sweden)

Radouane Oubabi

2014-03-01

Full Text Available The hemisynthesis of the title compound, C22H32O2, was carried out through direct acetylation reaction of the naturally occurring diterpene totarol [systematic name: (4bS,8aS-4b,8,8-trimethyl-1-propan-2-yl-5,6,7,8a,9,10-hexahydrophenanthren-2-ol]. The molecule is built up from three fused six membered rings, one saturated and two unsaturated. The central unsaturated ring has a half-chair conformation, whereas the other unsaturated ring displays a chair conformation. The absolute configuration is deduced from the chemical pathway. The value of the Hooft parameter [−0.10 (6] allowed this absolute configuration to be confirmed.

Germany: energy transition or revolution

International Nuclear Information System (INIS)

Boulanger, V.

2013-01-01

Germany has decided to phase out nuclear power by 2022 but it wants also to get rid of fossil energies by 2050. Those ambitious goals imply to be able to cut by half the demand for primary energy by 2050 which will be only possible if the need for building heating is cut by 80%, the constraint on transport is less important: one million of electrical vehicles will have to be on the road by 2020 and 3 millions 10 years later. In 2012 the production of electricity was made mainly from coal (44.7%), renewable energies (21.9%), nuclear energy (16%), natural gas (11.3%) and other energies (fuel...) (6.1%). Today the renewable energy sector is a major industrial sector in Germany, it represents about 382000 jobs directly or indirectly, it means more than the sector of conventional energies. (A.C.)

Multiculturalism in Germany

Directory of Open Access Journals (Sweden)

Milan Mesić

2010-12-01

Full Text Available The paper starts out from the recent statement by the German Chancellor Angela Merkel that multiculturalism in Germany is dead. The author draws attention to the unfavourable conditions for the development of multiculturalism in Germany. The reasons are historical, especially the experience of Nazism as well as the German social state. Namely, foreign workers in Germany, although without political rights and socially non-integrated, enjoyed a high degree of working and social rights, including high employment security. In this respect their position significantly differed from that of American workers (immigrants, which is why the struggle for civil rights was not in the foreground for German immigrants. Therefore, “the crisis of multiculturalism” appeared with the immigrants’ “second generation” (children, who have been first hit in the current times of crisis and the increasing deregulation of the labour market. They have remained socially non-integrated and without civil and political rights. It is interesting that the churches, particularly the Protestant one, lead in Germany in the efforts to begin to look at immigrants in a cultural (human sense as well, and have thus been the first to acknowledge that Germany has become a multicultural society. But this term and concept in Germany have remained sketchy, both in the theoretical and political sense. However, they have gained certain sympathy, mainly in parts of liberal-democratic circles – the Green Party leading the way – but more in a symbolic sense in countering xenophobia and cultural exclusion in German society. When multiculturalism was accused of developing “parallel society”, both the right and the left renounced it in favour of the (seemingly neutral concept of integration. The author proves that Germany has become and has remained multicultural, although not a multiculturalist country.

Solar brightness distribution at 8.6 mm from interferometer observations

International Nuclear Information System (INIS)

Kawabata, K.; Fujishita, M.; Kato, T.; Ogawa, H.; Omodaka, T.

1980-01-01

The radial brightness distribution of the quiet Sun at 8.6 mm is synthesized from observations using a sixteen element east-west interferometer in Nagoya. The observed brightness is flat from the disk center to 0.8 Rsub(sun). A slight darkening appeared between 0.8 Rsub(sun) and the limb. No evidence if the bright ring near the limb is found. The radio radius at 8.6 mm is 1.015 +- 0.005 Rsub(sun). In addition there exists a coronal component just outside the radio limb. (orig.)

7α-Methoxycarbonyl-6,7,8,14-tetrahydro-6,14-endo-ethenothebaine

Directory of Open Access Journals (Sweden)

Mustafa Odabaşoğlu

2009-04-01

Full Text Available In the molecule of the title compound, C23H27NO5, the furan ring adopts an envelope conformation. Intramolecular C—H...O interactions result in the formation of S(5 and S(6 motifs. In the crystal structure, weak intermolecular C—H...O hydrogen bonds link the molecules through C(6 and C(8 chains along the [100] and [010] directions, generating a two-dimensional network.

Synthesis and Screening of Modified 6,6'-Bis(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrobenzo[e][1,2,4]triazin-3-yl)-2,2'-bipyridine Ligands for Actinide and Lanthanide Separation in Nuclear Waste Treatment.

Science.gov (United States)

Afsar, Ashfaq; Distler, Petr; Harwood, Laurence M; John, Jan; Westwood, James

2016-11-04

Effects of chloro and bromo substitution at the 4-position of the pyridine ring of 6,6'-bis(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrobenzo[e][1,2,4]triazin-3-yl)-2,2'-bipyridine (CyMe 4 -BTBP) have been studied with regard to the extraction of Am(III) from Eu(III) and Cm(III) from 0.1-3 M HNO 3 . Similarly to CyMe 4 -BTBP, a highly efficient (D Am > 10 at 3 M HNO 3 ) and selective (SF Am/Eu > 100 at 3 M HNO 3 ) extraction was observed for Cl-CyMe 4 -BTBP and Br-CyMe 4 -BTBP in 1-octanol but in the absence of a phase-transfer agent.

42 CFR 8.6 - Withdrawal of approval of accreditation bodies.

Science.gov (United States)

2010-10-01

... PROVISIONS CERTIFICATION OF OPIOID TREATMENT PROGRAMS Accreditation § 8.6 Withdrawal of approval of... 42 Public Health 1 2010-10-01 2010-10-01 false Withdrawal of approval of accreditation bodies. 8.6... to establish that the problems that were grounds for withdrawal of approval have been resolved. (2...

Phenotypic differences of amyotrophic lateral sclerosis (ALS) in China and Germany.

Science.gov (United States)

Rosenbohm, Angela; Liu, Mingsheng; Nagel, Gabriele; Peter, Raphael S; Cui, Bo; Li, Xiaoguang; Kassubek, Jan; Rothenbacher, Dietrich; Lulé, Dorothée; Cui, Liying; Ludolph, Albert C

2018-04-01

The aim of this study is to explore phenotypical differences of amyotrophic lateral sclerosis (ALS) between two cohorts from Germany and China. Registry-based studies of ALS were conducted in South-West Germany from 2010 to 2014 and an ALS clinic in Beijing from 2013 to 2016, respectively. Demographic and clinical features of 663 German and 276 Chinese ALS patients were collected and compared. Mean age-at-onset was higher in German than in Chinese ALS patients [66.6 years (95% CI 65.7, 67.5) vs. 53.2 years (95% CI 52.0, 54.5)]. Age distribution of ALS patients peaked around 70-74 years in Germany and 50-54 years in China. Bulbar onset was more prevalent among German than among Chinese patients (35.9 vs. 22.8%). Diagnostic delay was higher in the Chinese than in the German study sample (12 vs. 5 months). Cognitive deficits were more pronounced in the Chinese cohort. Both cohorts differed in smoking habits, prevalence of diabetes and in body mass index (BMI). The apparent discrepancies between German and Chinese ALS patients (age at onset, gender distribution, bulbar forms, cognitive dysfunction, risk factors) reveal a quite different clinical phenotype in China, maybe due to socioeconomic status, environmental factors or genetic background. The observed differences in phenotype need to be pursued by further epidemiological studies on environmental and genetic risk factors.

Electronic structure of Ag8GeS6

Directory of Open Access Journals (Sweden)

D.I. Bletskan

2017-04-01

Full Text Available For the first time, the energy band structure, total and partial densities of states of Ag8GeS6 crystal were calculated using the ab initio density functional method in LDA and LDA+U approximations. Argyrodite is direct-gap semiconductor with the calculated band gap width Egd = 1.46 eV in the LDA+U approximation. The valence band of argyrodite contains four energy separated groups of occupied subzones. The unique feature of electron-energy structure of Ag8GeS6 crystal is the energy overlapping between the occupied d-states of Ag atoms and the delocalized valence p-states of S atoms in relatively close proximity to the valence band top.

Decreasing seroprevalence of herpes simplex virus type 1 and type 2 in Germany leaves many people susceptible to genital infection: time to raise awareness and enhance control.

Science.gov (United States)

Korr, Gerit; Thamm, Michael; Czogiel, Irina; Poethko-Mueller, Christina; Bremer, Viviane; Jansen, Klaus

2017-07-06

Herpes simplex infections (HSV1/2) are characterized by recurrent symptoms, a risk of neonatal herpes, and the facilitation of HIV transmission. In Germany, HSV1/2 infections are not notifiable and data are scarce. A previous study found higher HSV1/2 seroprevalences in women in East Germany than in women in West Germany. We assessed changes in the HSV1/2 seroprevalences over time and investigated determinants associated with HSV1/2 seropositivity to guide prevention and control. The study was based on the German Health Interview and Examination Survey for Adults (DEGS; 2008-2011) and the German National Health Interview and Examination Survey (GNHIES; 1997-1999). We tested serum samples from DEGS participants for HSV1 and HSV2 immunoglobulin G. We used Pearson's χ 2 test to compare the HSV1/HSV2 seroprevalences in terms of sex, age, and region of residence (East/West Germany) and investigated potential determinants by calculating prevalence ratios (PR) with log-binomial regression. All statistical analyses included survey weights. In total, 6627 DEGS participants were tested for HSV1, and 5013 were also tested for HSV2. Overall, HSV1 seroprevalence decreased significantly from 1997-1999 (82.1%; 95%CI 80.6-83.6) to 2008-2011 (78.4%; 95%CI 77.8-79.7). In the same period, overall HSV2 seroprevalence decreased significantly from 13.3% (95%CI 11.9-14.9) to 9.6% (95%CI 8.6-10.8), notably in 18-24-year-old men (10.4 to 0%) in East Germany. Women were more likely than men to be seropositive for HSV1 (PR 1.1) or HSV2 (PR 1.6). A lower level of education, smoking, and not speaking German were associated with HSV1 in both sexes. Women of older age, who smoked, or had a history of abortion and men of older age or who had not attended a nursery school during childhood were more often seropositive for HSV2. The reduced seroprevalences of HSV1 and HSV2 leave more people susceptible to genital HSV1/2 infections. Practitioners should be aware of HSV infection as a differential

Burnout experiments with 6 x 6, 8 x 8 and 7 x 7 rod bundle test sections using freon as model fluid

International Nuclear Information System (INIS)

Fulfs, H.; Katsaounis, A.; Minden, C.v.

1976-01-01

This paper reports on burnout experiments at staedy state condition using Freon12 as model fluid. The experiments were carried out with three test sections with 6 x 6, 8 x 8 and 7 x 7 rod bundles. The axial flux distribution of the rods is either constant or reactor like. The transformed measured points using STEVENS and BOURE scaling factors to equivalent water conditions respectively, were compared to the burnout correlation W3 using the reactor layout program DYNAMIT. The DYNAMIT code is a thermohydraulic lay-out reactor program without consideration of mixing flow between the subchannels. (orig.) [de

Conference on landscape impacts of wind energy and local acceptance: France-Germany crossed views

International Nuclear Information System (INIS)

Bouscatel, Jerome; Olagne, Regis; Derkenne, Chantal; Galiano, Mila; Mayer, Joerg; Ratzbor, Guenter; Laborgne, Pia; Nadai, Alain; Ratouis, Marie-Odile; Schoebel-Rutschmann, Soeren; Petit, Jean-Francois; Guennewig, Dieter; Portales, David

2008-01-01

The French-German office for Renewable energies (OFAEnR) organised a conference on the landscape impacts of wind energy. In the framework of this French-German exchange of experience, more than 100 participants exchanged views on the environmental impact of wind farms and the opinion of residents. This document brings together the available presentations (slides) made during this event: 1 - French people and wind energy (Mila Galiano); 2 - Wind energy acceptance in Germany: an essential factor for the wind industry development (Joerg Mayer); 3 - Taking into account landscapes and residents in the development of wind farms: a France-Germany comparison (Pia Laborgne, Alain Nadai); 3 - Wind energy development supervision thanks to territorial planning in Germany (Guenter Ratzbor); 4 - Landscape challenges in wind energy development: point of view and role of a state decentralised department (Marie-Odile Ratouis); 5 - Park or landscape - Wind turbines as elements of the cultural landscape (Soeren Schoebel-Rutschmann); 6 - How should a developer approach the 'landscape' aspect when foreseeing a wind energy project installation (Jean-Francois Petit); 7 - More consensual wind energy projects along highways, railways and overhead power lines? (Dieter Guennewig); 8 - The 'wings top': un example of participatory and citizen's project (David Portales)

ECFA SURVEY: Germany

International Nuclear Information System (INIS)

Anon.

1994-01-01

Few nations can match the scope of German basic physics contributions. Earlier this century, illustrious names (Rontgen, Franck, von Laue, Planck, Sommerfeld, Heisenberg, ) kept Germany among the front runners. Subsequent history has given German physics a very different profile - the country now participates massively in international projects and is the largest single contributing nation in CERN's research programme. At the same time, an impressive high energy programme at the German national Laboratory at DESY, Hamburg, centred around the 6.3 kilometre HERA ring, the world's only high energy electron-proton collider, attracts scientists from all over the world

High performance ZIF-8/6FDA-DAM mixed matrix membrane for propylene/propane separations

KAUST Repository

Zhang, Chen; Dai, Ying; Johnson, Justin R.; Karvan, Oguz; Koros, William J.

2012-01-01

We report significantly enhanced propylene/propane (C 3H 6/C 3H 8) selectivity in mixed matrix membranes fabricated using 6FDA-DAM polyimide and a zeolitic imidazolate framework (ZIF-8). Equilibrium isotherms and sorption kinetics of C 3H 6 and C 3H 8 at 35°C were studied on a 200nm commercially available ZIF-8 sample produced by BASF. Mixed matrix dense films were formed with 6FDA-DAM and 200nm BASF ZIF-8 particles. SEM imaging showed generally good adhesion between the ZIF-8 and 6FDA-DAM without the need for surface-treating ZIF-8. Pure gas permeation showed significantly enhanced mixed matrix ZIF-8/6FDA-DAM membrane C 3H 6/C 3H 8 separation performance over the pure 6FDA-DAM membrane performance. A C 3H 6 permeability of 56.2Barrer and C 3H 6/C 3H 8 ideal selectivity of 31.0 was found in ZIF-8/6FDA-DAM mixed matrix membrane with 48.0wt% ZIF-8 loading, which are 258% and 150% higher than the pure 6FDA-DAM membrane, respectively for permeability and selectivity. Permeation properties of C 3H 6 and C 3H 8 in ZIF-8 were back-calculated by the Maxwell model for composite permeability using pure gas permeation data, leading to a C 3H 6 permeability of 277Barrer and C 3H 6/C 3H 8 selectivity of 122. Mixed gas permeation also verified that selectivity enhancements were achievable in mixed gas environment by ZIF-8. © 2011 Elsevier B.V.

High performance ZIF-8/6FDA-DAM mixed matrix membrane for propylene/propane separations

KAUST Repository

Zhang, Chen

2012-02-01

We report significantly enhanced propylene/propane (C 3H 6/C 3H 8) selectivity in mixed matrix membranes fabricated using 6FDA-DAM polyimide and a zeolitic imidazolate framework (ZIF-8). Equilibrium isotherms and sorption kinetics of C 3H 6 and C 3H 8 at 35°C were studied on a 200nm commercially available ZIF-8 sample produced by BASF. Mixed matrix dense films were formed with 6FDA-DAM and 200nm BASF ZIF-8 particles. SEM imaging showed generally good adhesion between the ZIF-8 and 6FDA-DAM without the need for surface-treating ZIF-8. Pure gas permeation showed significantly enhanced mixed matrix ZIF-8/6FDA-DAM membrane C 3H 6/C 3H 8 separation performance over the pure 6FDA-DAM membrane performance. A C 3H 6 permeability of 56.2Barrer and C 3H 6/C 3H 8 ideal selectivity of 31.0 was found in ZIF-8/6FDA-DAM mixed matrix membrane with 48.0wt% ZIF-8 loading, which are 258% and 150% higher than the pure 6FDA-DAM membrane, respectively for permeability and selectivity. Permeation properties of C 3H 6 and C 3H 8 in ZIF-8 were back-calculated by the Maxwell model for composite permeability using pure gas permeation data, leading to a C 3H 6 permeability of 277Barrer and C 3H 6/C 3H 8 selectivity of 122. Mixed gas permeation also verified that selectivity enhancements were achievable in mixed gas environment by ZIF-8. © 2011 Elsevier B.V.

On-call service of neurosurgeons in Germany: organization, use of communication services, and personal acceptance of modern technologies.

Science.gov (United States)

Brenke, Christopher; Lassel, Elke A; Terris, Darcey; Kurt, Aysel; Schmieder, Kirsten; Schoenberg, Stefan O; Weisser, Gerald

2014-05-01

A significant proportion of acute care neurosurgical patients present to hospital outside regular working hours. The objective of our study was to evaluate the structure of neurosurgical on-call services in Germany, the use of modern communication devices and teleradiology services, and the personal acceptance of modern technologies by neurosurgeons. A nationwide survey of all 141 neurosurgical departments in Germany was performed. The questionnaire consisted of two parts: one for neurosurgical departments and one for individual neurosurgeons. The questionnaire, available online and mailed in paper form, included 21 questions about on-call service structure; the availability and use of communication devices, teleradiology services, and other information services; and neurosurgeons' personal acceptance of modern technologies. The questionnaire return rate from departments was 63.1% (89/141), whereas 187 individual neurosurgeons responded. For 57.3% of departments, teleradiology services were available and were frequently used by 62.2% of neurosurgeons. A further 23.6% of departments described using smartphone screenshots of computed tomography (CT) images transmitted by multimedia messaging service (MMS), and 8.6% of images were described as sent by unencrypted email. Although 47.0% of neurosurgeons reported owning a smartphone, only 1.1% used their phone for on-call image communication. Teleradiology services were observed to be widely used by on-call neurosurgeons in Germany. Nevertheless, a significant number of departments appear to use outdated techniques or techniques that leave patient data unprotected. On-call neurosurgeons in Germany report a willingness to adopt more modern approaches, utilizing readily available smartphones or tablet technology. Georg Thieme Verlag KG Stuttgart · New York.

The human papillomavirus (HPV) E6 oncoproteins promotes nuclear localization of active caspase 8

Energy Technology Data Exchange (ETDEWEB)

Manzo-Merino, Joaquin [Unidad de Investigación Biomédica en Cáncer, Instituto Nacional de Cancerología, México/Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México. Av. San Fernando No. 22, Col. Sección XVI, Tlalpan 14080 (Mexico); Massimi, Paola [International Centre for Genetic Engineering and Biotechnology, Padriciano 99, I-34149 Trieste (Italy); Lizano, Marcela, E-mail: lizanosoberon@gmail.com [Unidad de Investigación Biomédica en Cáncer, Instituto Nacional de Cancerología, México/Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México. Av. San Fernando No. 22, Col. Sección XVI, Tlalpan 14080 (Mexico); Banks, Lawrence, E-mail: banks@icgeb.org [International Centre for Genetic Engineering and Biotechnology, Padriciano 99, I-34149 Trieste (Italy)

2014-02-15

The HPV-16 E6 and E6{sup ⁎} proteins have been shown previously to be capable of regulating caspase 8 activity. We now show that the capacity of E6 to interact with caspase 8 is common to diverse HPV types, being also seen with HPV-11 E6, HPV-18 E6 and HPV-18 E6{sup ⁎}. Unlike most E6-interacting partners, caspase 8 does not appear to be a major proteasomal target of E6, but instead E6 appears able to stimulate caspase 8 activation, without affecting the overall apoptotic activity. This would appear to be mediated in part by the ability of the HPV E6 oncoproteins to recruit active caspase 8 to the nucleus. - Highlights: • Multiple HPV E6 oncoproteins interact with the caspase 8 DED domain. • HPV E6 stimulates activation of caspase 8. • HPV E6 promotes nuclear accumulation of caspase 8.

The human papillomavirus (HPV) E6 oncoproteins promotes nuclear localization of active caspase 8

International Nuclear Information System (INIS)

Manzo-Merino, Joaquin; Massimi, Paola; Lizano, Marcela; Banks, Lawrence

2014-01-01

The HPV-16 E6 and E6 ⁎ proteins have been shown previously to be capable of regulating caspase 8 activity. We now show that the capacity of E6 to interact with caspase 8 is common to diverse HPV types, being also seen with HPV-11 E6, HPV-18 E6 and HPV-18 E6 ⁎ . Unlike most E6-interacting partners, caspase 8 does not appear to be a major proteasomal target of E6, but instead E6 appears able to stimulate caspase 8 activation, without affecting the overall apoptotic activity. This would appear to be mediated in part by the ability of the HPV E6 oncoproteins to recruit active caspase 8 to the nucleus. - Highlights: • Multiple HPV E6 oncoproteins interact with the caspase 8 DED domain. • HPV E6 stimulates activation of caspase 8. • HPV E6 promotes nuclear accumulation of caspase 8

Upregulation of the Creatine Transporter Slc6A8 by Klotho

Directory of Open Access Journals (Sweden)

Ahmad Almilaji

2014-11-01

Full Text Available Background/Aims: The transmembrane Klotho protein contributes to inhibition of 1,25(OH2D3 formation. The extracellular domain of Klotho protein could function as an enzyme with e.g. β-glucuronidase activity, be cleaved off and be released into blood and cerebrospinal fluid. Klotho regulates several cellular transporters. Klotho protein deficiency accelerates the appearance of age related disorders including neurodegeneration and muscle wasting and eventually leads to premature death. The main site of Klotho protein expression is the kidney. Klotho protein is also appreciably expressed in other tissues including chorioid plexus. The present study explored the effect of Klotho protein on the creatine transporter CreaT (Slc6A8, which participates in the maintenance of neuronal function and survival. Methods: To this end cRNA encoding Slc6A8 was injected into Xenopus oocytes with and without additional injection of cRNA encoding Klotho protein. Creatine transporter CreaT (Slc6A8 activity was estimated from creatine induced current determined by two-electrode voltage-clamp. Results: Coexpression of Klotho protein significantly increased creatine-induced current in Slc6A8 expressing Xenopus oocytes. Coexpression of Klotho protein delayed the decline of creatine induced current following inhibition of carrier insertion into the cell membrane by brefeldin A (5 µM. The increase of creatine induced current by coexpression of Klotho protein in Slc6A8 expressing Xenopus oocytes was reversed by β-glucuronidase inhibitor (DSAL. Similarly, treatment of Slc6A8 expressing Xenopus oocytes with recombinant human alpha Klotho protein significantly increased creatine induced current. Conclusion: Klotho protein up-regulates the activity of creatine transporter CreaT (Slc6A8 by stabilizing the carrier protein in the cell membrane, an effect requiring β-glucuronidase activity of Klotho protein.

Drug-eluting stents with biodegradable polymer for the treatment of patients with diabetes mellitus: clinical outcome at 2 years in a large population of patients

Directory of Open Access Journals (Sweden)

Wiemer M

2015-02-01

Full Text Available Marcus Wiemer,1 Gian Battista Danzi,2 Nick West,3 Vassilios Voudris,4 René Koning,5 Stefan Hoffmann,6 Mario Lombardi,7 Josepa Mauri,8 Rade Babic,9 Fraser Witherow10On behalf of the NOBORI 2 Investigators 1Department of Cardiology, Heart and Diabetes Center North Rhine–Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany; 2Ospedale Maggiore Policlinico, Milan, Italy; 3Papworth Hospital, Cambridge, UK; 4Onassis Cardiac Surgery Center, Athens, Greece; 5Clinique Saint Hilaire, Rouen, France; 6Vivantes Netzwerk für Gesundheit GmbH, Berlin, Germany; 7Azienda Ospedaliera Villa Sofia, Palermo, Italy; 8Hospital Universitari Germans Trias i Pujol, Badalona, Spain; 9Institute for Cardiovascular Diseases Dedinje, Belgrade, Serbia; 10Dorset County Hospital, Dorchester, UK Objective: This study investigates the safety and efficacy of a third-generation drug-eluting stent (DES with biodegradable polymer in the complex patient population of diabetes mellitus (DM. Clinical trial registration: ISRCTN81649913. Background: Percutaneous coronary interventions in patients with DM are associated with a higher incidence of death, restenosis, and stent thrombosis as compared to non-diabetic patients. The use of a DES has been shown to improve outcomes in diabetic patients. Methods: Out of 3,067 patients, enrolled in 126 centers worldwide in the NOBORI 2 registry, 888 patients suffered from DM, 213 of them (14% being insulin-dependent DM (IDDM. Two years’ follow-up has been completed in this study. Results: At 1- and 2-year follow-up, 97% and 95% of the patients, respectively, were available. The reported target lesion failure (TLF rates at 1- and 2-year follow-up were 6.0% and 7.2% in the DM group, respectively, and 3.0% and 4.2% in the non-DM group, respectively (P<0.001 for both years. Inside the DM group, the TLF rates of 9.9% and 11.7% at the 1- and 2-year follow-ups, respectively, in patients with IDDM were significantly higher than the TLF rates of 4

National Ignition Facility subsystem design requirements target area auxiliary subsystem SSDR 1.8.6

International Nuclear Information System (INIS)

Reitz, T.

1996-01-01

This Subsystem Design Requirement (SSDR) establishes the performance, design, development, and test requirements for the Target Area Auxiliary Subsystems (WBS 1.8.6), which is part of the NIF Target Experimental System (WBS 1.8). This document responds directly to the requirements detailed in NIF Target Experimental System SDR 003 document. Key elements of the Target Area Auxiliary Subsystems include: WBS 1.8.6.1 Local Utility Services; WBS 1.8.6.2 Cable Trays; WBS 1.8.6.3 Personnel, Safety, and Occupational Access; WBS 1.8.6.4 Assembly, Installation, and Maintenance Equipment; WBS 1.8.6.4.1 Target Chamber Service System; WBS 1.8.6.4.2 Target Bay Service Systems

Emerging mosquito species in Germany-a synopsis after 6 years of mosquito monitoring (2011-2016).

Science.gov (United States)

Kampen, Helge; Schuhbauer, Astrid; Walther, Doreen

2017-12-01

Globalisation and climate change are the main drivers of invasion of non-endemic regions by mosquitoes. Mass transportation of people, animals and goods facilitate accidental long-distance displacement while climate warming supports active spread and establishment of thermophilic species. In the framework of a mosquito-monitoring programme, eight non-indigenous culicid species have been registered in Germany since 2011, with four of them being more or less efficient vectors of disease agents and another four now considered established. The eight newly emerged species include Aedes albopictus, Ae. japonicus, Ae. aegypti, Ae. koreicus, Ae. berlandi, Ae. pulcritarsis, Anopheles petragnani and Culiseta longiareolata. We here review recent findings and at the same time present new findings of specimens of non-native mosquito species in Germany.

7 CFR 8.6 - Authorization for use.

Science.gov (United States)

2010-01-01

... Office of the Secretary of Agriculture 4-H CLUB NAME AND EMBLEM § 8.6 Authorization for use. (a) The... use of the 4-H Club Name and Emblem: (1) For educational or informational uses which the Cooperative... use the 4-H Club Name and Emblem may be obtained from the Administrator of the Cooperative State...

Ramstein AB, Landstuhl, Germany. Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A-F

Science.gov (United States)

1978-10-10

hl KI A AR!TU SIl 1 Farstein AB Germany AB IMAR 52 MAR 63 N 49 25 E 007 35 789 ft 808 ft 24 2 Same APR 63 MAY 68 ISame Same Same 826 ft 24 3 sae Same...ffrmcenter of rj Sae aiD 1 f V& & 1407 ft from touchdown point of I rnwey 27 & 1300 ft from touch~down point of rnwy 09. ___ , ___ __ __,, USAF 52AC...1~ .c1 .±___ _____O b 9 4&4/ 43 .2 2.6- Z.7 1 .. 3o of ob o6- 4t2/ 41 - .0 2.1-1 L. 4-± *61 73i 6. 4140 / 39 L___ 503 -.2 *1 8:.4 351 -7 . 490 4.. 80

Oil and Gas Emergency Policy: Germany 2012 update

Energy Technology Data Exchange (ETDEWEB)

NONE

2012-07-01

state-owned storage facilities. Operators of gas storage facilities must grant other companies access to their storage facilities and auxiliary services at a fair market price. There are 47 gas storage facilities in Germany, with a total capacity 20.9 bcm. German firms also have access to natural gas storage in Haidach (Austria) which has a capacity of 2.6 bcm.

Refractive surgery trends and practice style changes in Germany over a 3-year period.

Science.gov (United States)

Schmack, Ingo; Auffarth, Gerd U; Epstein, Daniel; Holzer, Mike P

2010-03-01

To study the current practice styles and preferences of refractive surgeons in Germany. In February 2008, a seven-item questionnaire regarding the practice of refractive surgery was mailed to 282 members of the German Society of Intra-ocular Lens Implantation, Interventional, and Refractive Surgery (DGII) and the Commission of Refractive Surgery (KRC). Most questions were identical to our 2005 German refractive surgery survey. All data were analyzed in a masked fashion. The response rate was 42.2%. The majority (68%) of respondents reported that they perform refractive surgery in laser centers (exclusively or partially) followed by general hospitals (19.4%) and universities (12.6%). Although LASIK was the predominant type of refractive surgery performed (80.6%), other refractive procedures included refractive lens exchange (60.2%), photorefractive keratectomy (47.6%), phakic intraocular lens implants (45.6%), laser-assisted subepithelial keratectomy (36.9%), epithelial laser in situ keratomileusis (15.5%), intracorneal rings (5.8%), and limbal relaxing incisions (2.9%). The volume of refractive surgery procedures and the preferred type of excimer laser systems, microkeratomes, and diagnostic devices varied at different institutions. Most respondents performed either wavefront-guided custom ablation or wavefront-optimized ablation (63.1%) compared with conventional excimer laser correction (36.9%). Refractive surgery practice styles and preferences in Germany are comparable to trends in other European countries. Although LASIK is the most commonly performed refractive procedure, the numbers of various surface ablation techniques and refractive intraocular lens procedures are increasing. Copyright 2010, SLACK Incorporated.

Mortality factors and diseases in free-ranging Eurasian cranes (Grus grus) in Germany.

Science.gov (United States)

Fanke, Jane; Wibbelt, Gudrun; Krone, Oliver

2011-07-01

Detailed postmortem examinations were performed on 167 free-ranging Eurasian Cranes (Grus grus) from Germany, collected between September 1998 and December 2008 to evaluate causes of death and diseases. The most common causes of mortality were traumatic injuries (n=105, 62.9%) from collisions with power lines (n=39, 23.4%) and wire fences (n=12, 7.2%). A group of 28 Eurasian Cranes (16.8%) died from organophosphate intoxication. Predation by White-tailed Sea Eagles (Haliaeetus albicilla) and red foxes (Vulpes vulpes) occurred in four cases (2.4%). Pathologic changes due to infectious diseases were associated with Aspergillus spp. (n=7, 4.2%), endoparasites (n=7, 4.2%), avian poxvirus (n=6, 3.6%), Mycobacterium spp. (n=2, 1.2%), and adenovirus infection (n=1, 0.6%). A severe Strigea spp. infection (n=1, 0.6%) and a leiomyosarcoma (n=1, 0.6%) were newly recognized diseases in Eurasian Cranes in this study.

Energy transition in France and Germany

International Nuclear Information System (INIS)

Persem, Melanie

2014-01-01

This document presents some key figures and comparisons between the French and German energy plans: electricity mix, 2003-2013 evolution of installed power and of renewable electrical production, cost of energy transition (evolution of charges relative to contracts of renewable electricity purchasing agreement), 2004-2013 evolution employment in renewable energies industry, France-Germany power exchanges (France import balance of 9.8 TWh in 2013), electricity goals in the French and German energy transitions

[Assisted suicide in Germany: medical diagnoses and personal reasons of 117 decedents].

Science.gov (United States)

Bruns, F; Blumenthal, S; Hohendorf, G

2016-02-01

In Germany both scientific and public debates on physician assisted suicide often focus on patients with unbearable suffering in terminal condition. Proponents of physician assisted suicide bring forward the argument that there are end-of-life situations where only assisted suicide can bring relief from intolerable pain, dyspnea or other symptoms. But does focusing on unbearable symptoms in terminal condition reflect the reality of assisted suicide? Our data from 117 assisted suicides in Germany indicates that the reasons for assisted suicide are more complex than the current debate in Germany suggests. We analyzed diagnoses and reasons that prompted patients to suicide with the help of the German right-to-die organization "Sterbehilfe Deutschland" (StHD) between 2010 and 2013. 118 case reports of assisted suicide published by StHD were evaluated retrospectively. Between 2010 and 2013 StHD provided assistance in 118 suicides. 71 % of the deceased were women. 67 % were aged 70 years or older. 25,6 % suffered from metastasized cancer, 20,5 % had a severe neurological disease. 23 % suffered from age-associated diseases or disability. 14,5 % of the decedents had a predominant psychiatric diagnose, 7,7 % were physically and mentally healthy. The main reasons for suicide were loss of life perspective in the face of a severe disease (29 %), fear of care dependency (23,9 %), weariness of life without any severe disease (20,5 %). Only 12,8 % named non-treatable symptoms as a reason. Loss of life perspective in the face of a severe disease, fear of long-term care and weariness of life without any severe disease rather than unbearable suffering of non-treatable symptoms seem to be the most common reasons for members of StHD to commit suicide. These empirical findings should be mentioned in future debates on assisted suicide in Germany. © Georg Thieme Verlag KG Stuttgart · New York.

Health-related use of the Internet in Germany 2007

Directory of Open Access Journals (Sweden)

Lausen, Berthold

2008-09-01

Full Text Available The European eHealth Trends project analyses the attitudes towards and usage of eHealth applications of European citizens in the time frame 2005–2007. In April/May 2007 the second series of representative stratified surveys with computer-based telephone interviews (CATI (in Germany based on the German ADM Master Sample were performed by a poll agency in seven European countries. Here we report the major results for the German population, were 1000 participants with an age between 15 and 80 years were interviewed. For the general use of the Internet for health purposes as well as the established eHealth Internet use (at least once a month we report a significant increase (from 44.4% to 56.6% and from 22.5% to 32.0%. Further, the percentage of Germans who consider the Internet as an important medium for health purposes increased from 33.7% to 36.8%. In Bavaria, the percentage of established eHealth Internet users was lowest among the German states. The results of our eHealth Trends survey in Germany show a considerable increase of eHealth use within the last 18 months. German physicians need to be prepared for an increasing number of empowered patients, who have searched for information on their health problems in the Internet, but will also demand more enhanced services.

Isolation of 8-hydroxyglycitein and 6-hydroxydaidzein from soybean miso.

Science.gov (United States)

Hirota, Akira; Inaba, Miyuki; Chen, Yu-Chi; Abe, Naoki; Taki, Shoji; Yano, Masamichi; Kawaii, Satoru

2004-06-01

We isolated from soybean miso 8-hydroxyglycitein and 6-hydroxydaidzein as DPPH-radical scavengers, and elucidated their chemical structures by mass spectrometric, and (1)H- and (13)C-NMR spectrosopic analyses. These compounds showed DPPH-radical scavenging activity as high as that of alpha-tocopherol, 8-hydroxygenistein and 8-hydroxydaidzein. This is the first report of the isolation of 8-hydroxyglycitein from a natural source.

Imidazopyridine-5,6,7,8-tetrahydro-8-quinolinamine derivatives with potent activity against HIV-1.

Science.gov (United States)

Gudmundsson, Kristjan S; Boggs, Sharon D; Catalano, John G; Svolto, Angilique; Spaltenstein, Andrew; Thomson, Michael; Wheelan, Pat; Jenkinson, Stephen

2009-11-15

Synthesis of several novel imidazopyridine-5,6,7,8-tetrahydro-8-quinolinamine derivatives with potent activity against HIV are described. Synthetic approaches allowing for variation of the substitution pattern are outlined and resulting changes in antiviral activity and pharmacokinetics are highlighted. Several compounds with low nanomolar anti-HIV activity and oral bioavailability are described.

Germany, Russia, and energy

International Nuclear Information System (INIS)

Paillard, Christophe Alexandre

2007-01-01

This article first recalls and comments the objectives defined in March 2007 by the European Council in terms of energy to struggle against climate change. These objectives relate to the reduction of greenhouse gas emissions, to renewable energies, to energy saving, and to the share of biofuels. It outlines that Germany worries about the political situation in Russia and the capacities of this country to supply Europe with hydrocarbons. Figures related to consumption of primary energy and to sources of production of electricity in Germany show that Germany is facing an increased energy dependency. The issues related to the relationship between the EU and Russia in the field of energy are further discussed, notably from the German point of view, but also from a European point of view as the EU expects a stronger reaction of Germany in front of the Russian situation

The nonstructural protein 8 (nsp8) of the SARS coronavirus interacts with its ORF6 accessory protein

International Nuclear Information System (INIS)

Kumar, Purnima; Gunalan, Vithiagaran; Liu Boping; Chow, Vincent T.K.; Druce, Julian; Birch, Chris; Catton, Mike; Fielding, Burtram C.; Tan, Yee-Joo; Lal, Sunil K.

2007-01-01

Severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) caused a severe outbreak in several regions of the world in 2003. The SARS-CoV genome is predicted to contain 14 functional open reading frames (ORFs). The first ORF (1a and 1b) encodes a large polyprotein that is cleaved into nonstructural proteins (nsp). The other ORFs encode for four structural proteins (spike, membrane, nucleocapsid and envelope) as well as eight SARS-CoV-specific accessory proteins (3a, 3b, 6, 7a, 7b, 8a, 8b and 9b). In this report we have cloned the predicted nsp8 gene and the ORF6 gene of the SARS-CoV and studied their abilities to interact with each other. We expressed the two proteins as fusion proteins in the yeast two-hybrid system to demonstrate protein-protein interactions and tested the same using a yeast genetic cross. Further the strength of the interaction was measured by challenging growth of the positive interaction clones on increasing gradients of 2-amino trizole. The interaction was then verified by expressing both proteins separately in-vitro in a coupled-transcription translation system and by coimmunoprecipitation in mammalian cells. Finally, colocalization experiments were performed in SARS-CoV infected Vero E6 mammalian cells to confirm the nsp8-ORF6 interaction. To the best of our knowledge, this is the first report of the interaction between a SARS-CoV accessory protein and nsp8 and our findings suggest that ORF6 protein may play a role in virus replication

POLYCYCLIC AROMATIC HYDROCARBONS WITH STRAIGHT EDGES AND THE 7.6/6.2 AND 8.6/6.2 INTENSITY RATIOS IN REFLECTION NEBULAE.

Science.gov (United States)

Ricca, Alessandra; Bauschlicher, Charles W; Roser, Joseph E; Peeters, Els

2018-01-01

We have investigated the mid-infrared spectral characteristics of a series of polycyclic aromatic hydrocarbons (PAHs) with straight edges and containing an even or odd number of carbons using density functional theory (DFT). For several even and odd-carbon PAHs, the 8.6/6.2 and 7.6/6.2 intensity ratios computed in emission after the absorption of a 8 eV photon match the observed ratios obtained for three reflection nebulae (RNe), namely NGC 1333, NGC 7023, and NGC 2023. Odd-carbon PAHs are favored, particularly for NGC 1333. Both cations and anions are present with the cations being predominant. Relevant PAHs span sizes ranging from 46 to 103-113 carbons for NGC 7023 and NGC 2023 and from 38 to 127 carbons for NGC 1333 and have symmetries ranging from D 2 h to C s . Our work suggests that even and odd-carbon PAHs with straight edges are viable candidates for the PAH emission seen towards irradiated Photo-Dissociation Regions (PDRs).

Polycyclic Aromatic Hydrocarbons with Straight Edges and the 7.6/6.2 and 8.6/6.2 Intensity Ratios in Reflection Nebulae

Science.gov (United States)

Ricca, Alessandra; Bauschlicher, Charles W., Jr.; Roser, Joseph E.; Peeters, Els

2018-02-01

Using density functional theory, we have investigated the mid-infrared spectral characteristics of a series of polycyclic aromatic hydrocarbons (PAHs) that have straight edges and that contain an even or odd number of carbons. For several even and odd-carbon PAHs, the 8.6/6.2 and 7.6/6.2 intensity ratios computed in emission after the absorption of a 8 eV photon match the observed ratios obtained for three reflection nebulae (RNe), namely NGC 1333, NGC 7023, and NGC 2023. Odd-carbon PAHs are favored, particularly for NGC 1333. Both cations and anions are present, with the cations being predominant. Relevant PAHs span sizes ranging from 46 to 113 carbons for NGC 7023 and NGC 2023 and from 38 to 127 carbons for NGC 1333, and have symmetries ranging from D2h to C s . Our work suggests that even- and odd-carbon PAHs with straight edges are viable candidates for the PAH emission seen toward irradiated photodissociation regions.

Drugs in East Germany.

Science.gov (United States)

Dressler, J; Müller, E

1997-09-01

Germany was divided into two parts after World War II. The closed border and a nonconvertible currency in the Eastern part were the factors that did not allow a drug market to develop. Alcohol and medicaments were used as substitute drugs. Since Germany was reunified 5 years ago, there are now the same conditions prevailing for the procurement and sale of drugs in East Germany as there are in the Western German states. This report describes the current state of drug traffic, especially in Saxony, under the new social conditions.

Page 1 _ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - ' -......6-6-5 ...

African Journals Online (AJOL)

and to evaluate the risk factors for the virus, we under- rook a seroprevalence study in the Ngwelezane district of Natal/KwaZulu. ... in Africa.8-1, However, the reliability of some of these estimates is ... pIes were further subjected to a Select HTLV test. .... Diagnostic Products, Wiesbaden-Delkenheim, Germany and HIV ...

Acculturation and Depressive Symptoms among Turkish Immigrants in Germany

Directory of Open Access Journals (Sweden)

Eva Morawa

2014-09-01

Full Text Available The present study explores the impact of acculturation on depressive symptoms among Turkish immigrants in Germany, taking into account different dimensions of cultural orientation. A total of 471 patients from two selected samples (254 primary care patients and 217 outpatients of a psychosomatic department participated. Levels of acculturation were measured as orientation towards culture of origin (CO, and orientation towards the host culture (HC. Acculturation strategies (integration, assimilation, separation, and marginalization were also assessed as well as their association with depressive symptoms (BDI. Furthermore, gender- and migration-related differences in terms of acculturation and levels of depressive symptomatology were analyzed. Integration was the acculturation strategy associated with the lowest level of depressive symptoms (M = 14.6, SD = 11.9, while marginalization was associated with the highest (M = 23.5, SD = 14.7. Gender was not found to have a significant impact on acculturation but influenced depressive symptoms, with women (M = 21.8, SD = 13.3 reporting higher levels of depressive symptomatology than men (M = 15.1, SD = 14.0; p < 0.001. In first generation immigrants, significantly higher CO (M = 46.6, SD = 8.3; p < 0.001, lower HC (M = 31.0, SD = 9.6; p < 0.001, and higher levels of depressive symptoms (M = 20.2, SD = 14.1; p < 0.001 were found in comparison to second generation immigrants (CO: M = 41.3, SD = 7.4; HC: M = 36.2, SD = 8.8; depressive symptoms: M = 14.0, SD = 12.9. Our results suggest that orientation towards both the heritage and the host culture has a positive effect on the mental health status of immigrants. Future research needs to include representative samples of migrants from different cultures to further explore the association between acculturation and mental health.

Germany, Pacifism and Peace Enforcement

DEFF Research Database (Denmark)

Dalgaard-Nielsen, Anja

This book is about the transformation of Germany's security and defence policy in the time between the 1991 Gulf War and the 2003 war against Iraq. It traces and explains the reaction of Europe's biggest and potentially most powerful country to the ethnic wars of the 1990s, the emergence of large...... the 1990s. The book debates the implications of Germany's transformation for Germany's partners and neighbours, and explains why Germany said ‘yes’ to the war in Afghanistan, but ‘no’ to the Iraq War. Based on a comprehensive study of the debates of the German Bundestag and actual German policy responses...

Geometry task & drill sheets : grades 6-8

CERN Document Server

Rosenberg, Mary

2011-01-01

For grades 6-8, our Common Core State Standards-based combined resource meets the geometry concepts addressed by the NCTM standards and encourages the students to review the concepts in unique ways. The task sheets introduce the mathematical concepts to the students around a central problem taken from real-life experiences, while the drill sheets provide warm-up and timed practice questions for the students to strengthen their procedural proficiency skills.

Weimar Germany

DEFF Research Database (Denmark)

Reckendrees, Alfred

2015-01-01

The Weimar Republic is analysed within the concept of limited and open access orders. Before World War I, Imperial Germany had developed into a mature limited access order with rule of law and open economic access but lack of competition in politics. After World War I and inflation, Weimar Germany...... developed toward an open access order; open access was not, however, sustainable and collapsed in 1930–31. This case of a failed open access order suggests refining the framework of limited and open access orders in further work. It shows that the political process of “creative destruction” might result...

Survival of Patients with Oral Cavity Cancer in Germany

Science.gov (United States)

Listl, Stefan; Jansen, Lina; Stenzinger, Albrecht; Freier, Kolja; Emrich, Katharina; Holleczek, Bernd; Katalinic, Alexander; Gondos, Adam; Brenner, Hermann

2013-01-01

The purpose of the present study was to describe the survival of patients diagnosed with oral cavity cancer in Germany. The analyses relied on data from eleven population-based cancer registries in Germany covering a population of 33 million inhabitants. Patients with a diagnosis of oral cavity cancer (ICD-10: C00-06) between 1997 and 2006 are included. Period analysis for 2002–2006 was applied to estimate five-year age-standardized relative survival, taking into account patients' sex as well as grade and tumor stage. Overall five-year relative survival for oral cavity cancer patients was 54.6%. According to tumor localization, five-year survival was 86.5% for lip cancer, 48.1% for tongue cancer and 51.7% for other regions of the oral cavity. Differences in survival were identified with respect to age, sex, tumor grade and stage. The present study is the first to provide a comprehensive overview on survival of oral cavity cancer patients in Germany. PMID:23349710

[Publication performances of university clinics for anesthesiology: Germany, Austria and Switzerland from 2001 to 2010].

Science.gov (United States)

Putzer, G; Ausserer, J; Wenzel, V; Pehböck, D; Widmann, T; Lindner, K; Hamm, P; Paal, P

2014-04-01

This study assessed the publication performance of university departments of anesthesiology in Austria, Germany and Switzerland. The number of publications, original articles, impact factors and citations were evaluated. A search was performed in PubMed to identify publications related to anesthesiology from 2001 to 2010. All articles from anesthesiology journals listed in the fields of anesthesia/pain therapy, critical care and emergency medicine by the "journal citation report 2013" in Thomson Reuters ISI web of knowledge were included. Articles from non-anaesthesiology journals, where the stem of the word anesthesia (anes*, anaes*, anäst*, anast*) appears in the affiliation field of PubMed, were included as well. The time periods 2001-2005 and 2006-2010 were compared. Articles were allocated to university departments in Austria, Germany and Switzerland via the affiliation field. A total of 45 university departments in Austria, Germany and Switzerland and 125,979 publications from 2,863 journals (65 anesthesiology journals, 2,798 non-anesthesiology journals) were analyzed. Of the publications 23 % could not be allocated to a given university department of anesthesiology. In the observation period the university department of anesthesiology in Berlin achieved most publications (n = 479) and impact points (1,384), whereas Vienna accumulated most original articles (n = 156). Austria had the most publications per million inhabitants in 2006-2010 (n=50) followed by Switzerland (n=49) and Germany (n=35). The number of publications during the observation period decreased in Germany (0.5 %), Austria (7 %) and Switzerland (8 %). Tables 2 and 4-8 of this article are available at Springer Link under Supplemental. The research performance varied among the university departments of anesthesiology in Germany, Austria and Switzerland whereby larger university departments, such as Berlin or Vienna published most. Publication output in Germany, Austria and

Multiple proton decays of 6Be, 8C, 8B(IAS) and excited states in 10C

Science.gov (United States)

Sobotka, Lee

2011-10-01

Recent technical advances have allowed for high-order correlation experiments to be done. We have primarily focused on experiments in which the final channels are composed of only alphas and protons. Four cases we have studied are: 6Be, 10C*, 8C, and 8B*(IAS) via 3, 4, 5, and 3-particle correlation measurements, respectively. While the first case had been studied before, our work presents very high statistics in the full Jacobi coordinates (the coordinates needed to describe 3-body decay.) Our study of 10C excited states provides isolatable examples of: correlated 2p decay, from one state, and the decay of another which is unusually highly correlated, a ``ménage a quatre.'' 8C decay presents the only case of sequential 3-body 2p decay steps (i.e. 2p-2p.) The intermediate in this 2-step process is the first example (6Be) mentioned above. Unlike the well-studied second step (6Be decay), the first step in this 2p-2p process provides another example of correlated 2p emission. The decay of 8B(IAS), the isobaric analog of 8C, also decays overwhelmingly by 2p emission, in this case to 6Li(IAS). This IAS-to-IAS 2p decay is one for which decay to the potential 1p intermediates is energetically allowed but isospin forbidden. This represents an expansion, over that originally envisioned by Goldanski, of the conceivable nuclear territory for 2p decay.

Synthesis and reactions of 4-(p-methoxybenzyl-6-[5,6,7,8-tetrahydro-2-naphthyl]-pyridazin-3(2H-one

Directory of Open Access Journals (Sweden)

NAGWA M.S. EL-DIN HARB

1999-11-01

Full Text Available The condensation of 4-(p-methoxybenzyl-6-[5,6,7,8-tetrahydro-2-naphthyl]-pyridazin-3(2H-one (3, prepared by the reaction of 6-[5,6,7,8-tetrahydro-2-naphthyl]-4,5-dihydropyridazin-3(2H-one (1 and anisaldehyde, with dimethyl sulphate, formaldehyde and acrylonitrile, and also the formation of the Mannich base, proceeded smoothly at the 2-position to give compounds 4,5,6,7, respectively. 4-p-Methoxybenzyl-3-chloro-6-[5,6,7,8-tetrahydro-2-naphthyl]-pyridazine (9 was prepared in law yield by the action of phosphorus oxychloride on 3. The reaction of 9 with benzylamine, aniline and piperidine gave 10a,b,c, respectively. 4-p-Methoxybenzyl-6-[5,6,7,8-tetrahydro-2-napthyl]pyridazine-3(2H-thione (12 was prepared either by the action of thiourea on 9, or by the reaction of 3 with phosphorus pentasulphide. The reaction of these thiones with acrylonitrile, morpholine and piperidine to give 13 and 14 a,b, respectively, were also investigated.

Radiochemical studies relevant to the production of sup 8 sup 6 Y and sup 8 sup 8 Y at a small-sized cyclotron

CERN Document Server

Kettern, K; Spellerberg, S; Coenen, H H; Qaim, S M

2002-01-01

Excitation functions were measured by the stacked-foil technique for sup n sup a sup t Sr(p,xn) sup 8 sup 8 sup , sup 8 sup 7 sup m sup , sup g Y reactions from threshold up to 25 MeV. From the measured cross sections integral yields of sup 8 sup 8 Y, sup 8 sup 7 mY and sup 8 sup 7 sup g Y were calculated. The optimum energy range for the production of sup 8 sup 8 Y is Ep=14->9 MeV; the sup 8 sup 8 Y yield amounts to 1.75 MBq (47.3 mu Ci/mu A.h) and the sup 8 sup 7 Y and sup 8 sup 7 sup m Y impurities to 2.0 and 4.4%, respectively. The isomeric cross section ratio for the pair sup 8 sup 7 sup m sup , sup g Y was determined as a function of incident proton energy and the results are discussed in terms of the spins of the two isomeric states involved. Medium scale production of both sup 8 sup 6 Y and sup 8 sup 8 Y has been carried out more than 15 times each using the (p,n) reaction. In the former case 96.3% enriched sup 8 sup 6 SrCO sub 3 was used as target material, and in the latter sup n sup a sup t SrCO su...

Calibration setting numbers for dose calibrators for the PET isotopes "5"2Mn, "6"4Cu, "7"6Br, "8"6Y, "8"9Zr, "1"2"4I

International Nuclear Information System (INIS)

Wooten, A. Lake; Lewis, Benjamin C.; Szatkowski, Daniel J.; Sultan, Deborah H.; Abdin, Kinda I.; Voller, Thomas F.; Liu, Yongjian; Lapi, Suzanne E.

2016-01-01

For PET radionuclides, the radioactivity of a sample can be conveniently measured by a dose calibrator. These devices depend on a “calibration setting number”, but many recommended settings from manuals were interpolated based on standard sources of other radionuclide(s). We conducted HPGe gamma-ray spectroscopy, resulting in a reference for determining settings in two types of vessels containing one of several PET radionuclides. Our results reiterate the notion that in-house, experimental calibrations are recommended for different radionuclides and vessels. - Highlights: • Dose calibrators measure radioactivity by ionization of gas from emitted radiation. • Accuracy of dose calibrators depends on “calibration setting numbers” for isotopes. • Many manufacturer settings are interpolated from emissions of other radionuclides. • As a high-precision reference, HPGe gamma-ray spectroscopy was conducted. • New calibrations were found for PET isotopes "5"2Mn, "6"4Cu, "7"6Br, "8"6Y, "8"9Zr, and "1"2"4I.

Cegelec Germany

International Nuclear Information System (INIS)

2011-01-01

Cegelec is a group of companies acting internationally and one of Europe's biggest plant engineering firms in the fields of power generation and distribution with the focus on engineering and technical services. Cegelec's competences in Germany are mainly in planning, installation and maintenance of plants and facilities in all key industries and for public clients. The main areas of activity are industry, infrastructure and power, for which Cegelec offers comprehensive project and service work. While the Industry business area covers chemistry, steel, paper, automotive, re-engineering, and mining industries, Cegelec's Infrastructure unit performs services to airports, in tunnel construction, for railways and waterways. The Power market segment comprises gas, refuse incineration, power supply, sugar, power plants, and nuclear final storage. Cegelec is represented in Germany on roughly 30 locations with a staff of 1,700. The origins of Cegelec are in Germany, i.e. in AEG founded 1896. The Plant and Automation Technology sector was divested in 1996 and moved to Alstom where, in 2001, a management buyout led to the independent Cegelec group of companies. When the strategic partnership between Qatari Diar and Vinci took shape, Cegelec became a subsidiary of the Vinci group in April 2010. (orig.)

Population, mortality and place of death in Germany (1950-2050) - implications for end-of-life care in the future.

Science.gov (United States)

Simon, S T; Gomes, B; Koeskeroglu, P; Higginson, I J; Bausewein, C

2012-11-01

European populations are ageing, but data on the associated end-of-life care needs are scarce. This study aimed to analyse population, mortality and place of death (PoD) trends in Germany since 1950, and to project mortality by PoD until 2050. Secondary analysis of national statistics on population, mortality and PoD by age and gender. Future numbers and proportions of deaths by PoD - hospital deaths (HDs) and non-hospital deaths (NHDs) - were based on recent trends (2005-2009). Linear models accounted for the effect of age and gender. The German population increased by 19.0% between 1950 and 2002, and has remained relatively stable ever since. However, it is expected that it will decrease (15.4%) from 2009 to 2050 (from 81.8 to 69.4 million). The annual number of deaths has shown an increasing trend, except for a decrease in 1975-2004. A 26.0% increase is expected from 2009 to 2050 (854,544 to 1,077,000 deaths). Older people (age ≥ 75 years) will account for 87.8% of all deaths in 2050 (64.4% in 2009). The proportion of HDs was stable, with an annual mean of 47.0% (range 44.9-47.8%). The models estimated that most people will continue to die outside of hospital in 2050 (48.6 or 54.1%), and absolute numbers of both HDs and NHDs will increase from 2009 to 2050 [HD: by 20.1 million (30.6%); NHD: by 35.5 million (17.0%)]. Unlike in other industrialized countries, most people in Germany die outside of hospital. The need to plan for growing end-of-life care needs and ageing is urgent in Germany but also applies to the rest of Europe. A joint European policy must inform national strategies. Copyright © 2012 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

Parasites of sheep herding dogs in central Germany.

Science.gov (United States)

Rehbein, Steffen; Kaulfuß, Karl-heinz; Visser, Martin; Sommer, Maria Franziska; Grimm, Felix; Silaghi, Cornelia

2016-01-01

This paper reports on endoparasite infections diagnosed in 2012 by standard coproscopical techniques and coproantigen Giardia ELISA in 165 dogs used for sheep herding in 36 farms in central Germany. The overall prevalence of dogs with evidence of endoparasite infections was 27.3% (95% CI 20.6-34.7). The most frequently identified faecal forms were those of ascarids (Toxocara, 6.7%; Toxascaris 3.6%), hookworms (5.5%) and taeniid cestodes (4.2%), followed by those of Trichuris whipworms (3.0%), Capillaria aerophila (1.8%), Angiostrongylus and Crenosoma lungworms (1.2% each) and Cystoisospora canis coccidians (0.6%). Molecular identification demonstrated the seven dogs shedding taeniid eggs positive for Taenia (T.) species tapeworms (five, T. hydatigena; one, T. ovis; one Taenia sp.). Screening of the faeces with the coproantigen ELISA revealed Giardia specific antigen in 5.5% of the samples. The majority of the dogs had evidence of single endoparasite infections (22.4%) while evidence for infection with two or three parasites concurrently was found in six (3.6%) and two (1.2%) of the dogs, respectively. Dogs ≤ 1 year (n = 19) were parasitized more frequently (p < 0.05) with overall gastrointestinal parasites (63.2% vs. 20.5%), ascarids (36.8% vs. 6.8%) and Giardia spp. (21.1% vs. 3.4%) than older dogs (n = 146). Dogs which had been wormed within six months of examination tested less frequently positive for gastrointestinal helminths compared to dogs not wormed (11.1% vs. 25.0%; p = 0.0567). In addition, ear swabs taken from 43 sheep dogs in 2012 were examined, and Otodectes cynotis mites were extracted from one dog. Identification of ectoparasites collected by full body search and combing from 113 sheep dogs in the years 2011 to 2013 revealed infestation of fleas and ticks (each up to five specimens per dog) on 13 and 108 dogs, respectively, with nine dogs carrying both fleas and ticks. Archaeopsylla erinacei, Ctenocephalides (C) canis, C. felis and Pulex irritans

Use of complementary and alternative medicine in patients with multiple sclerosis in Germany.

Science.gov (United States)

Gotta, Mario; Mayer, Christoph A; Huebner, Jutta

2018-02-01

The use of complementary and alternative medicine (CAM) for chronic diseases such as multiple sclerosis (MS) is becoming an increasingly important issue for those affected. Especially in Germany there are only a few studies dealing with CAM, as yet. The aim of this study was to assess the prevalence, the methods used, the subjective benefits as well as physician/patient communication. A structured questionnaire including demographic and disease-specific data, CAM use, perceived benefits as well as physician/patient communication was sent to real and web-based self-help groups for MS in Germany. 343 answers could be evaluated. 77.3% of the participants were females. The mean age was 45.0 ± 11.9 years and the duration of the disease was 12.0 ± 9.6 years. 81.9% said they were using CAM, nearly half (44.8%) used it alternatively to conventional medicine. The average number of CAM- methods used were 3.6. The most popular methods were vitamin supplements, Yoga/Thai chi/Qi Gong, relaxation techniques and meditation. Approximately half (139/49.5%) of CAM users disclosed this to their treating neurologist. Yet, 37,6% have doubts on the competence of the respective physician. Patients with MS have a strong interest in CAM. Usage as alternative therapy is widespread and puts patients at risk of progress of the disease. As patient/physician communication on the topic is increasing, neurologists should be attentive to guiding their patients through safe complementary methods. Copyright © 2017 Elsevier Ltd. All rights reserved.

Germany at CERN

CERN Document Server

2001-01-01

The Eighth Exhibition of German Industry, "Germany at CERN" started this week and offers German companies the opportunity to establish professional contacts with CERN. From left to right in the foreground: Maximilian Metzger (BMBF), Bettinna Schöneseffen (BMBF), Karl-Heinz Kissler (SPL division leader), Horst Wenninger, and Hans Hoffman. Behind and to the right of Karl-Heinz Kissler is His Excellency Mr Walter Lewalter, Ambassador and permanent representative of Germany to the UN office in Geneva.

Data analysis & probability drill sheets : grades 6-8

CERN Document Server

Forest, Chris

2011-01-01

For grades 6-8, our Common Core State Standards-based resource meets the data analysis & probability concepts addressed by the NCTM standards and encourages your students to review the concepts in unique ways. Each drill sheet contains warm-up and timed drill activities for the student to practice data analysis & probability concepts.

Challenges dealing with depleted uranium in Germany - Reuse or disposal

International Nuclear Information System (INIS)

Moeller, Kai D.

2007-01-01

During enrichment large amounts of depleted Uranium are produced. In Germany every year 2.800 tons of depleted uranium are generated. In Germany depleted uranium is not classified as radioactive waste but a resource for further enrichment. Therefore since 1996 depleted Uranium is sent to ROSATOM in Russia. However it still has to be dealt with the second generation of depleted Uranium. To evaluate the alternative actions in case a solution has to be found in Germany, several studies have been initiated by the Federal Ministry of the Environment. The work that has been carried out evaluated various possibilities to deal with depleted uranium. The international studies on this field and the situation in Germany have been analyzed. In case no further enrichment is planned the depleted uranium has to be stored. In the enrichment process UF 6 is generated. It is an international consensus that for storage it should be converted to U 3 O 8 . The necessary technique is well established. If the depleted Uranium would have to be characterized as radioactive waste, a final disposal would become necessary. For the planned Konrad repository - a repository for non heat generating radioactive waste - the amount of Uranium is limited by the licensing authority. The existing license would not allow the final disposal of large amounts of depleted Uranium in the Konrad repository. The potential effect on the safety case has not been roughly analyzed. As a result it may be necessary to think about alternatives. Several possibilities for the use of depleted uranium in the industry have been identified. Studies indicate that the properties of Uranium would make it useful in some industrial fields. Nevertheless many practical and legal questions are open. One further option may be the use as shielding e.g. in casks for transport or disposal. Possible techniques for using depleted Uranium as shielding are the use of the metallic Uranium as well as the inclusion in concrete. Another

Rotavirus vaccine effectiveness in preventing hospitalizations due to gastroenteritis: a descriptive epidemiological study from Germany.

Science.gov (United States)

Pietsch, C; Liebert, U G

2018-04-10

Rotavirus infections are common causes of infant hospitalization. The present study examined the effectiveness of anti-rotavirus vaccination in preventing rotavirus-related hospitalizations in Germany, following its state and nationwide introductions in 2008 and 2013, respectively. During 15 consecutive seasons 9557 stool samples of hospitalized children of 5 years and younger with acute gastroenteritis were screened for rotavirus A. Rotavirus G and P genotypes were assessed after vaccine introduction. Vaccine effectiveness was determined by comparison of rotavirus incidence in pre-vaccine and post-vaccine cohorts. The herd effect was calculated as the difference between the observed reduction of rotavirus-related hospitalizations and the expected direct vaccine effect. The number of rotavirus-related hospitalizations declined after vaccine introduction. Approximately 26% (503/1955) of prevented cases could be attributed to the herd effect. Human rotaviruses of genotypes G3P[8], G1P[8], G9P[8], G4P[8], G2P[4] and G12P[8] were most frequent. Uncommon genotypes remained rare. The direct, indirect, total and overall vaccine effectiveness was 86% (95% confidence interval (CI) 83.2-89.1%), 48% (95% CI 42.8-52.6%), 93% (95% CI 91.3-94.3%) and 69% (95% CI 66.5-72.0%), respectively. There was no significant difference in vaccine-type or in genotype-specific vaccine effectiveness. Anti-rotavirus vaccination efficiently reduced rotavirus-related hospitalizations in Germany in the past decade. The vaccines analysed in this article provide a broadly heterologous and long-lasting protection. The herd effect substantially contributed to the observed drop in the number of incidences of severe rotavirus infections. Presumably, constant high vaccine coverage will lead to a continued upward trend in the overall vaccine efficiency. Copyright © 2018 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

Financing long term liabilities (Germany)

International Nuclear Information System (INIS)

2003-01-01

charges and fees levied from the waste producers. Altogether, financial resources for decommissioning are needed for the following steps: the post-operational phase in which the facility is prepared for dismantling after its final shut-down, dismantling of the radioactive part of the facility, management, storage and disposal of the radioactive waste, restoration of the site, licensing and regulatory supervision of all these steps. Additional means are necessary for the management, storage and disposal of the spent fuel. The way in which the availability of financial resources is secured differs between public owned installations and installations of the private power utilities. In Germany, past practices has resulted in singular contaminated sites of limited extent, mainly during the first half of the 20. century. Those contaminated sites have been or are being cleaned up and redeveloped. In large areas of Saxony and Thuringia, the geological formations permitted the surface and underground mining of Uranium ore. Facilities of the former Soviet-German WISMUT Ltd. where ore was mined and processed from 1946 until the early 1990's can be found at numerous sites. In the course of the re-unification of Germany, the soviet shares of the WISMUT were taken over by the Federal Republic of Germany and the closure of the WISMUT facilities was initiated. In that phase the extent of the damages to the environment and of the necessary remediation work became clear. All mining and milling sites are now closed and are under decommissioning. A comprehensive remediation concept covers all WISMUT sites. Heaps and mill-tailing ponds are transferred into a long-term stable condition. The area of the facilities to be remediated amounts to more than 30 km 2 . Heaps cover a total area of ca. 15,5 km 2 , tailing ponds in which the tailings resulting from the Uranium production are stored as sludges cover 6,3 km 2 ). In total, the remediation issues are very complex and without precedent. The

IR, FT-ICR-MS studies on (1'S, 6'S)-1-cyclopropyl-7-(2,8-diazabicyclo[4.3.0] non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride salt.

Science.gov (United States)

Lin, Zhiwei

2014-01-01

The infrared spectra of (1'S, 6'S)-1-cyclopropyl-7-(2,8-diazabicyclo[4.3.0] non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride salt (CLF-HCl) were studied and compared with free base. Their fragmentation pathways were investigated using tandem mass spectrometric (MS/MS) techniques on Fourier-transform ion cyclotron resonance spectrum, and many characteristic fragment ions were found. Copyright © 2013 Elsevier B.V. All rights reserved.

Selection statements of the Federal Government of Germany of the 8th legislative period. Pt. 2

International Nuclear Information System (INIS)

Mayer, G.

1980-02-01

This selection of opinions of the Government of the Federal Republic of Germany covers the total fuel circuit. It is classified in a lucid index and the complete texts of the questioning of the Bundestag and the answers given by the Federal Government. Questions and answers are put directly one after the other to obtain a better view. (Publications of the Bundestag and plenary minutes). (HP) [de

"6"8Gallium-arginine-glycine-aspartic acid and "1"8F-fluorodeoxyglucose position emission tomography/computed tomography in chondroblastic osteosarcoma of the skull

International Nuclear Information System (INIS)

Orunmuyi, Akintunde; Modiselle, Moshe; Lengana, Thabo; Ebenhan, Thomas; Vorster, Mariza; Sathekge, Mike

2017-01-01

We report the case of a 32 year-old male with Chondroblastic Osteosarcoma of the skull, which was imaged with both "1"8[F]fluorodeoxyglucose ("1"8F-FDG) positron emission tomography/computed tomography (PET/CT) and "6"8Gallium-arginine-glycine-aspartic acid ("6"8Ga-RGD) PET/CT. The "1"8F-FDG PET/CT did not demonstrate the tumour, whereas the "6"8Ga-RGD PET/CT clearly depicted a left-sided frontal tumour. "6"8Ga-RGD PET/CT may be a clinically useful imaging modality for early detection of recurrent osteosarcoma, considering the limitations of "1"8F-FDG PET in a setting of low glycolytic activity

Anxiety and depression in adult patients with familial Mediterranean fever: a study comparing patients living in Germany and Turkey.

Science.gov (United States)

Giese, Arnd; Örnek, Ahmet; Kilic, Levent; Kurucay, Mustafa; Şendur, Süleyman N; Lainka, Elke; Henning, Bernhard F

2017-12-01

To determine the prevalence of anxiety and depression among patients with familial Mediterranean fever (FMF) living in Germany or Turkey a prospective study was conducted. Forty FMF patients living in Turkey (T), 40 FMF patients living in Germany (G) and 40 healthy controls living in Germany (C) were included. Patients and controls were of Turkish ancestry. G were compared to T and C. The Hospital Anxiety and Depression Scale (HADS) was used with a cut-off of ≥ 8 for each subdomain score (HADS-A, HADS-D). Baseline characteristics of G were comparable to T and C except for age (T: 30.5 years, G: 35.2 years, C: 34.6 years; T vs. G P = 0.045), duration of disease (T: 14.4 years, G: 24; P < 0.001), C-reactive protein (T: 0.78 mg/dL, G: 0.78 mg/dL, C: 0.35 mg/dL; G vs. C P = 0.03). Prevalence of anxiety was higher in G compared to C (T: 65%, G: 52.5%, C: 22.5%: G vs. C P < 0.05). No difference was found for the prevalence of depression (T: 30%, G: 35%, C: 20%). The association between FMF and anxiety in subjects living in Germany persisted after adjusting for age and gender in a regression analysis and was robust to an adjustment for coexisting depression. Anxiety and depression did not correlate with FMF disease severity assessed with the Pras score. Anxiety, but not depression is more common among FMF patients living in Germany compared to healthy controls. No significant difference could be found between FMF patients living in Germany or Turkey concerning the prevalence of anxiety or depression. © 2014 Asia Pacific League of Associations for Rheumatology and Wiley Publishing Asia Pty Ltd.

Magnetism and superconductivity in Eu(Ho)Mo6S8

International Nuclear Information System (INIS)

Capone, D.W. II; Lai Fook, M.S.; Guertin, R.P.; Hinks, D.G.; Dunlap, B.D.; Foner, S.; Abou-Aly, A.I.; Brooks, J.S.

1984-10-01

A variety of ambient and high pressure experimental results reveal the interplay between magnetism and superconductivity in Ho doped samples of the pressure induced superconductor, EuMo 6 S 8 . Ho concentrations up to 50 atomic percent of the rare earth ions were used. High resolution magnetic measurements are consistent with the crystalline electric field ground state for the Ho 3+ ions being a magnetic doublet consisting largely of J/sub z/ = 18. The results of high pressure magnetization experiments reveal negligible effects of reduced lattice constant on the rare earth-rare earth interactions. Resistivity in a 10 atomic percent sample for P = 10 kbar shows the suppression of a P = 0 structural transition, metallic conductivity down to low temperatures, and finally superconductivity at 8 K. The upper critical field, H/sub c2/(T), for this sample was measured for P = 7, 10 and 12 kbar and showed strong reentrant behavior (dH/sub c2/(T)/dT > 0 as T → 0 K). A minimum with field in the resistivity above H/sub c2/ was also observed at lowest temperatures. The H/sub c2/(T) data are compared with those of EuMo 6 S 8 at high pressure, which shows positive curvature, and HoMo 6 S 8 , in which superconductivity is quenched by ferromagnetism at low temperatures. 14 references, 4 figures

Germany: Management of decommissioning waste in Germany

International Nuclear Information System (INIS)

Borrmann, F.; Brennecke, P.; Koch, W.; Kugel, K.; Steyer, S.

2007-01-01

Over the past two decades, Germany has gained a substantial amount of experience in the decommissioning of nuclear facilities of different types and sizes. Many research reactors and all prototype nuclear power plants, as well as a few larger nuclear power plants and fuel cycle facilities, are currently at varying stages of decommissioning. Several facilities have been fully dismantled and the sites have been cleared for reuse. The decommissioning projects comprise 18 power and prototype reactors, 33 research reactors and 11 fuel cycle facilities which are being or have been decommissioned. In the future, further nuclear power plants will be shut down and decommissioned in accordance with Germany?s energy policy to phase out the use of nuclear power for commercial electricity generation as given in the April 2002 amendment of the Atomic Energy Act. Radioactive waste, from operations as well as from decommissioning activities, is to be conditioned in such a way as to comply with the waste acceptance requirements of a repository. In Germany, all types of radioactive waste (i.e., short-lived and long-lived) are to be disposed of in deep geological formations. A distinction is being made for heat generating waste (i.e., high level waste) and waste with negligible heat generation (i.e., low level and intermediate level waste). Radioactive decommissioning waste is waste with negligible heat generation. Waste acceptance requirements of a repository are of particular importance for the conditioning of radioactive waste, including decommissioning waste. The waste acceptance requirements, as they resulted from the Konrad licensing procedure, are being applied by the waste generators for the conditioning of decommissioning waste. Compliance with these requirements must be demonstrated through the waste package quality control, even if the waste will be disposed of in the future. In 2002 the Konrad repository was licensed for the disposal of all types of waste with negligible

Neutron scattering studies of the coexistence of long-range magnetic order and superconductivity in Dy12Mo6S8 and Tb12Mo6S8

International Nuclear Information System (INIS)

Thomlinson, W.; Shirane, G.; Moncton, D.E.; Ishikawa, M.; Fischer, O.

1978-10-01

Both Dy 1 2 Mo 6 S 8 and Tb 1 2 Mo 6 S 8 are superconducting below T/sub c/ = 2.05 K. Neutron scattering studies show that these compounds in zero applied magnetic field develop long-range antiferromagnetic order (greater than 300 A) at T/sub M/ = 0.4 K and T/sub M/ = 1.0 K, respectively, which does not destroy the superconducting state. Magnetization measurements at temperatures below T/sub M/ suggest the development of ferromagnetic order as the applied magnetic field increases. In the case of Tb 1 2 Mo 6 S 8 the neutron data show long-range ferromagnetic order developing for H greater than or equal to H/sub c2/ = 1.9 kOe where H/sub c2/ is the upper critical field for superconductivity. However, for Dy 1 2 Mo 6 S 8 long-range ferromagnetic order begins to develop at H = 200 Oe, a field much less than H/sub c2/ = 1.2 kOe. As the ferromagnetic intensity increases, the antiferromagnetic intensity decreases. Between H = 200 Oe and H = 1.2 kOe both ferromagnetic and antiferromagnetic order occur with the sample in the superconducting state

Wind power report Germany 2014; Windenergie Report Deutschland 2014

Energy Technology Data Exchange (ETDEWEB)

Rohrig, Kurt (ed.)

2015-07-01

Record year 2014. In Germany, the expansion figures attained were so high on land and at sea that the overall new installation figure of 5,188 MW surpassed the previous maximum (from 2002) by more than 60%. With an overall capacity of 39,259 MW, for the first time, wind energy in Germany covers 9.7% of gross power consumption. On the global scale a capacity of more than 51,000 MW has been added - another record high for wind energy installations. Power mix. At 161 TWh, renewable energies in Germany covered 27.8% of gross power consumption and provided for the first time more energy than any other energy source. Coming into force of the new REA in August 2014, modified support schemes caused the expansion of biogas plants and large-scale PV installations to falter. The record expansion seen for wind energy can be interpreted as a pull-forward effect due to the tender procedures coming into force in 2017. Grid integration. Loss of production caused by feed-in management measures rose by 44% to 555 GWh as compared to 2012. Wind turbines were affected in 87% of cases but the impact on PV installations is increasing. Power generation must be more flexible and grids expanded to limit loss of production. Of the 23 expansion projects (1,887 km) in the Electricity Grid Expansion Act, just a quarter of them had been realized by the end of 2014 (463 km). In the preliminary analysis results for the 2014 grid development plan, the extent of grid upgrading and conversion was 3050 km. Offshore, the HelWin 1 grid link with a capacity of 580 MW went online. SylWin 1 and BorWin 2, with a total capacity of 1660 MW, are currently being tested in a trial. In the preliminary analysis results for the 2014 offshore grid development plan, grid connections having an overall capacity of 10.3 GW are planned. Onshore. 2014 saw a total of 44 different turbine types installed in Germany. For the first time, virtually the same number of turbines were added in the 3-4 MW class, as in the 2-3 MW

Have public attitudes in Germany towards nuclear energy changed?

International Nuclear Information System (INIS)

Gey, Angela

2000-01-01

The Federal Government developed its phase-out scenario in 1998, at a time in which the public debate about nuclear energy in Germany had waned and the anti-nuclear movement among the population had clearly lost much of its support. Since the beginning of the 90s, the proportion of Germans referring to themselves as 'opponents of nuclear power' has gone down from almost 19 to only just 12%. This decrease has been particularly strong among younger people. While in 1990 29 were still opposed to nuclear power, in 1999 this figure was only 17 %. Within the age group of 30-44 year-olds, 26 were against nuclear power in 1990; today, it is only 16 %. As for Germans aged 45+, the number of nuclear-power opponents decreased within this period by around 6 to a mere 8%. The issue of the 'use of nuclear power', which used to be ideologically charged and discussed with great passion in Germany for a long time, has cooled down. There exist quite different views about the further use of nuclear technology, and what the public wants especially in view of the planned phase-out is a prudent energy policy, based on a careful analysis of the consequences. One of the major points of the current opinion poll on the topic: 'Have public attitudes in Germany towards nuclear energy changed?', is being carried out by the Institut fur Demoskopie Alensbach on behalf of the Informationskreis Kernenergie. Apart from this first major point, this poll is to find out which general course an energy policy should ideally take according to public opinion, along which lines such an energy policy should orientate itself, what is the place value of the principle of having an energy mix, and how much importance is attributed to sustainability. Another focus lies on probing the knowledge of those polled in order to check to what extent the population assesses correctly the quantitative importance of nuclear power and alternative energies and how well it is informed about the potentials of different forms

[Fostering of health economics in Germany].

Science.gov (United States)

Ulrich, V

2012-05-01

Health economics is now well established in Germany with the aim to apply economic tools to answer problems in health and health care. After a short review of the international development of health economics and the development in Germany in particular, the article looks at selected recent topics of health economic analysis in Germany (economic evaluation, industrial economics, health and education).

Economic burden of advanced melanoma in France, Germany and the UK: a retrospective observational study (Melanoma Burden-of-Illness Study).

Science.gov (United States)

Grange, Florent; Mohr, Peter; Harries, Mark; Ehness, Rainer; Benjamin, Laure; Siakpere, Obukohwo; Barth, Janina; Stapelkamp, Ceilidh; Pfersch, Sylvie; McLeod, Lori D; Kaye, James A; Wolowacz, Sorrel; Kontoudis, Ilias

2017-12-01

The aim of this study was to estimate the cost-of-illness associated with completely resected stage IIIB/IIIC melanoma with macroscopic lymph node involvement, overall and by disease phase, in France, Germany and the UK. This retrospective observational study included patients aged older than or equal to 18 years first diagnosed with stage IIIB/IIIC cutaneous melanoma between 1 January 2009 and 31 December 2011. Data were obtained from medical records and a patient survey. Direct costs, indirect costs and patient out-of-pocket expenses were estimated in euros (€) (and British pounds, £) by collecting resource use and multiplying by country-specific unit costs. National annual costs were estimated using national disease prevalence from the European cancer registry and other published data. Forty-nine centres provided data on 558 patients (58.2% aged <65 years, 53.6% stage IIIB disease at diagnosis). The mean follow-up duration was 27 months (France), 26 months (Germany) and 22 months (UK). The mean total direct cost per patient during follow-up was €23 582 in France, €32 058 in Germany and €37 970 (£31 123) in the UK. The largest cost drivers were melanoma drugs [mean €14 004, €21 269, €29 750 (£24 385), respectively] and hospitalization/emergency treatment [mean: €6634, €6950, €3449 (£2827), respectively]. The total mean indirect costs per patient were €129 (France), €4,441 (Germany) and €1712 (£1427) (UK). Estimates for annual national direct cost were €13.1 million (France), €30.2 million (Germany) and €27.8 (£22.8) million (UK). The economic burden of stage IIIB/IIIC melanoma with macroscopic lymph node involvement was substantial in all three countries. Total direct costs were the highest during the period with distant metastasis/terminal illness.

Neurosurgical Resident Training in Germany.

Science.gov (United States)

Stienen, Martin N; Gempt, Jens; Gautschi, Oliver P; Demetriades, Andreas K; Netuka, David; Kuhlen, Dominique E; Schaller, Karl; Ringel, Florian

2017-07-01

Introduction  Efficient neurosurgical training is of paramount importance to provide continuing high-quality medical care to patients. In this era of law-enforced working hour restrictions, however, maintaining high-quality training can be a challenge and requires some restructuring. We evaluated the current status of resident training in Germany. Methods  An electronic survey was sent to European neurosurgical trainees between June 2014 and March 2015. The responses of German trainees were compared with those of trainees from other European countries. Logistic regression analysis was performed to assess the effect size of the relationship between a trainee being from Germany and the outcome (e.g., satisfaction, working time). Results  Of 532 responses, 95 were from German trainees (17.8%). In a multivariate analysis corrected for baseline group differences, German trainees were 29% as likely as non-German trainees to be satisfied with clinical lectures given at their teaching facility (odds ratio [OR]: 0.29; 95% confidence interval [CI]: 0.18-0.49; p  hours as requested from the European Working Time Directive 2003/88/EC, and in an international comparison, German trainees were twice as likely to work > 50 hours per week (OR: 2.13; 95% CI, 1.25-3.61; p  = 0.005). This working time, however, is less spent in the operating suite (OR: 0.26; 95% CI, 0.11-0.59; p  = 0.001) and more doing administrative work (OR: 1.83; 95% CI, 1.13-2.96; p  = 0.015). Conclusion  Some theoretical and practical aspects of neurosurgical training are superior, but a considerable proportion of relevant aspects are inferior in Germany compared with other European countries. The present analyses provide the opportunity for a critical review of the local conditions in German training facilities. Georg Thieme Verlag KG Stuttgart · New York.

The Lincoln Image in Germany

Directory of Open Access Journals (Sweden)

Jörg Nagler

2016-05-01

Full Text Available This essay investigates the enduring fascination with the sixteenth President of the United States in Germany. In general, his legacy and its evaluation changed in relation to the determinate historical contexts, beginning with the monarchial system, extending through the Weimar Republic, the Third Reich, and now the Federal Republic of Germany. Certain social and political individuals/groups in Germany used the image and iconography of Lincoln as a projection screen to support their own political objectives. Although there were always multiple layers of Lincoln representations in Germany, the dominant images were: the national unifier, the libertarian universalist, the emancipator, the defender of moral values, the modernizer, the democrat who used the power of the democratic state, the egalitarian self-made man from humble origins, and the defender of social justice and workingmen’s rights.

Structure of the 8He exotic nucleus by the direct reactions 8He(p, p')8He, 8He(p,d)7He and 8He(p,t)6He

International Nuclear Information System (INIS)

Skaza, Flore

2004-01-01

The elastic and inelastic scattering of an 8 He beam on a proton target have been measured at GANIL. The first 8 He beam produced by the SPIRAL facility at an energy of 15.6 A.MeV impinged on a proton target. The experimental setup was composed by the eight telescopes MUST array dedicated to the measure of the light charged particles, by a scintillator plastic wall for the detection of heavy projectile, and by two beam tracking detectors CATS for the measure event by event of the incident position and angle of the beam on the target. This setup allowed also to measure the one and two neutron transfer reactions 8 He(p,d) 7 He and 8 He(p,t) 6 He. The excitation energy spectrum for 6,7,8 He and the angular distributions associated to each reaction have been measured. The observed excited states are in agreement with the data of the literature. We indicate the presence of a first excited state for 7 He at 0.9 MeV and we give for the first time the position of a second excited state in 8 He at 5.4 MeV; the presence of such state was just suggested in a previous experiment. CCBA calculations allowed to extract a spectroscopic factor of 4.4 ± 1.4 for the pick-up of one neutron from 8 He to 7 He. This value is in agreement with a closed p3/2 sub-shell for 8 He. To analyse the angular distributions for elastic and inelastic scattering, it was necessary to take into account in the formalism used to describe the reactions, via coupled channels reactions calculations, the couplings to the one neutron transfer reaction. (author) [fr

EMAS in Germany. Evaluation 2012; EMAS in Deutschland. Evaluierung 2012

Energy Technology Data Exchange (ETDEWEB)

NONE

2013-03-15

Since the 1990ies, the Eco-Management and Audit Scheme (EMAS) is established in the European Union. Arqum GmbH (Munich, Germany) and Infra dimap (Berlin, Germany) performed the survey ''EMAS in Germany - Evaluation 2012'' at 573 EMAS organizations in the period between March 2012 and July 2012 in order to gain insight into the current EMAS practice in German organizations and to identify potentials for the future development of the EMAS system. The survey covered the following topics: (1) Reasons for participation of the companies and organizations with the EMAS system; (2) Cost-effectiveness of EMAS at the site of the organization; (3) Experiences with the environmental statement; (4) Experiences after the last EMAS amendment (EMAS III); (5) Experience with the environmental verifier and the validation process; (6) Evaluation of the continuation of the EMAS system; (7) Requests to the environmental policy. The main results of this survey are presented in the contribution under consideration.

Psycho-oncological care in certified cancer centres--a nationwide analysis in Germany.

Science.gov (United States)

Singer, Susanne; Dieng, Sebastian; Wesselmann, Simone

2013-06-01

Over the last few years, a nationwide voluntary certification system for cancer centres has been established in Germany. To qualify for certification, cancer centres must provide psycho-oncological care to every patient who needs it. The aim of this study was to find out how many patients have been treated by a psycho-oncologist in the certified centres. All cancer centres in Germany that were re-certified in 2010 provided data documenting how many patients with primary cancer received at least 30 min of psycho-oncological consultation in 2009. Data from n = 456 certified cancer centres were available. In the centres, a total of 36,165 patients were seen by a psycho-oncologist for at least 30 min, representing 37.3% of all patients in the centres. The highest percentage of patients who received psycho-oncological care was found in breast cancer centres (66.7%), and the lowest in prostate cancer centres (6.8%). Half of the patients (50.0%) in gynaecological cancer centres, 37.7% in colon cancer centres and 25.4% in lung cancer centres received psycho-oncological care. Compared with non-certified centres, the proportion of patients receiving psycho-oncological care in certified cancer centres has increased. Copyright © 2012 John Wiley & Sons, Ltd.

A Theoretical investigation of a potential high energy density compound 3,6,7,8-tetranitro-3,6,7,8-tetraaza-tricyclo[3.1.1.1(2,4]octane

Directory of Open Access Journals (Sweden)

Guozheng Zhao

2013-01-01

Full Text Available The B3LYP/6-31G (d density functional theory (DFT method was used to study molecular geometry, electronic structure, infrared spectrum (IR and thermodynamic properties. Heat of formation (HOF and calculated density were estimated to evaluate detonation properties using Kamlet-Jacobs equations. Thermal stability of 3,6,7,8-tetranitro-3,6,7,8-tetraaza-tricyclo [3.1.1.1(2,4]octane (TTTO was investigated by calculating bond dissociation energy (BDE at the unrestricted B3LYP/6-31G(d level. Results showed the N-NO2 bond is a trigger bond during the thermolysis initiation process. The crystal structure obtained by molecular mechanics (MM methods belongs to P2(1/C space group, with cell parameters a = 8.239 Å, b = 8.079 Å, c = 16.860 Å, Z = 4 and r = 1.922 g cm-3. Both detonation velocity of 9.79 km s-1 and detonation pressure of 44.22 GPa performed similarly to CL-20. According to the quantitative standards of energetics and stability, TTTO essentially satisfies this requirement as a high energy density compound (HEDC.

Voltage profile, structural prediction, and electronic calculations for MgxMo6S8

CSIR Research Space (South Africa)

Kganyago, KR

2003-03-01

Full Text Available the binary Mo6S8 and MgAMo6S8 ~see Table III!, the Mo-Mo distances decrease by (0.521)%. This decrease corresponds to an an- isotropic contraction of the Mo6 octahedron. The Mo cluster of the rhombohedral compounds forms an elongated octahe- dron of symmetry...

41 CFR 304-6.8 - Will the reports be made available for public inspection?

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false Will the reports be made available for public inspection? 304-6.8 Section 304-6.8 Public Contracts and Property Management Federal...-PAYMENT GUIDELINES Valuation § 304-6.8 Will the reports be made available for public inspection? Yes, OGE...

Reversing course: Germany`s response to the challenge of transboundary air pollution

Energy Technology Data Exchange (ETDEWEB)

Sprinz, D.F.; Wahl, A.

1998-03-01

Perhaps like no other country, Germany has radically changed its policies towards regulating air pollution in the European context. Acting originally as a dragger in the 1970s to regulate transboundary air pollutants due to pessimism about the relationship between causes and effects, Germany responded very decisively to its own damage assessment in the early 1980s. In particular the adverse effects to forests (`Waldsterben` or forest decline) led to the formulation of strict air pollution regulations in the domestic context, efforts to spread the regulatory system within the European Union, and activities within the United Nations Economic Commission for Europe to foster stronger, continent-wide emission reductions. Using three conceptual models (rational actor, domestic politics, and social learning), we show that Germany deviated strongly from the ideal policy cycle consisting of (i) domestic policy formulation, (ii) international negotiations, as well as (iii) implementation and compliance with the provisions of international environmental agreements. Both national policy-making as well as partial implementation have been well on the way towards compliance even before Germany entered international negotiations on substantive protocols. Therefore, one may conclude from this country study that push countries may use the results of their national policy processes to influence the policy of other countries. (orig.)

The effect of online gambling on gambling problems and resulting economic health costs in Germany.

Science.gov (United States)

Effertz, Tobias; Bischof, Anja; Rumpf, Hans-Jürgen; Meyer, Christian; John, Ulrich

2018-01-23

Problematic and pathological gambling have emerged as substantial problems in many countries. One potential accelerating factor for this phenomenon during recent years is the Internet, which offers different kinds of games and online applications for gambling that are faster, more attractive due to a variety of design and marketing options, less costly and potentially more addictive than terrestrial gambling opportunities. However, the contributing role of the Internet for problematic gambling has not been analyzed sufficiently so far and remains inconclusive. The current study is based on a representative sample with 15,023 individuals from Germany. With a new concept of assessing online gambling with its relative fraction of total gambling activities and a control-function approach to account for possible endogeneity of online gambling, we estimate the impact of online gambling on gambling behavior while additionally controlling for a rich set of important covariates, like education, employment situation and family status. The results show that, on average, replacing 10% of offline gambling with online gambling increases the likelihood of being a problematic gambler by 8.8-12.6%. This increase is equivalent to 139,322 problematic gamblers and 27.24 million € per year of additional expenditures in the German health sector. Our findings underpin the necessity to keep online gambling restricted to prevent further developments of problematic and pathological gambling in Germany.

High probability of comorbidities in bronchial asthma in Germany.

Science.gov (United States)

Heck, S; Al-Shobash, S; Rapp, D; Le, D D; Omlor, A; Bekhit, A; Flaig, M; Al-Kadah, B; Herian, W; Bals, R; Wagenpfeil, S; Dinh, Q T

2017-04-21

Clinical experience has shown that allergic and non-allergic respiratory, metabolic, mental, and cardiovascular disorders sometimes coexist with bronchial asthma. However, no study has been carried out that calculates the chance of manifestation of these disorders with bronchial asthma in Saarland and Rhineland-Palatinate, Germany. Using ICD10 diagnoses from health care institutions, the present study systematically analyzed the co-prevalence and odds ratios of comorbidities in the asthma population in Germany. The odds ratios were adjusted for age and sex for all comorbidities for patients with asthma vs. without asthma. Bronchial asthma was strongly associated with allergic and with a lesser extent to non-allergic comorbidities: OR 7.02 (95%CI:6.83-7.22) for allergic rhinitis; OR 4.98 (95%CI:4.67-5.32) allergic conjunctivitis; OR 2.41 (95%CI:2.33-2.52) atopic dermatitis; OR 2.47 (95%CI:2.16-2.82) food allergy, and OR 1.69 (95%CI:1.61-1.78) drug allergy. Interestingly, increased ORs were found for respiratory diseases: 2.06 (95%CI:1.64-2.58) vocal dysfunction; 1.83 (95%CI:1.74-1.92) pneumonia; 1.78 (95%CI:1.73-1.84) sinusitis; 1.71 (95%CI:1.65-1.78) rhinopharyngitis; 2.55 (95%CI:2.03-3.19) obstructive sleep apnea; 1.42 (95%CI:1.25-1.61) pulmonary embolism, and 3.75 (95%CI:1.64-8.53) bronchopulmonary aspergillosis. Asthmatics also suffer from psychiatric, metabolic, cardiac or other comorbidities. Myocardial infarction (OR 0.86, 95%CI:0.79-0.94) did not coexist with asthma. Based on the calculated chances of manifestation for these comorbidities, especially allergic and respiratory, to a lesser extent also metabolic, cardiovascular, and mental disorders should be taken into consideration in the diagnostic and treatment strategy of bronchial asthma. PREVALENCE OF CO-EXISTING DISEASES IN GERMANY: Patients in Germany with bronchial asthma are highly likely to suffer from co-existing diseases and their treatments should reflect this. Quoc Thai Dinh at Saarland

Incidence of anogenital warts in Germany: a population-based cohort study

Directory of Open Access Journals (Sweden)

Mikolajczyk Rafael T

2010-12-01

Full Text Available Abstract Background Human papilloma virus (HPV types 6 and 11 account for 90 percent of anogenital warts (AGW. Assessment of a potential reduction of the incidence of AGW following introduction of HPV vaccines requires population-based incidence rates. The aim of this study was to estimate incidence rates of AGW in Germany, stratified by age, sex, and region. Additionally, the medical practitioner (gynaecologist, dermatologist, urologist etc. who made the initial diagnosis of AGW was assessed. Methods Retrospective cohort study in a population aged 10 to 79 years in a population-based healthcare insurance database. The database included more than 14 million insurance members from all over Germany during the years 2004-2006. A case of AGW was considered incident if a disease-free period of twelve months preceded the diagnosis. To assess regional variation, analyses were performed by federal state. Results The estimated incidence rate was 169.5/100,000 person-years for the German population aged 10 to 79 years. Most cases occurred in the 15 to 40 years age group. The incidence rate was higher and showed a peak at younger ages in females than in males. The highest incidence rates for both sexes were observed in the city-states Berlin, Hamburg and Bremen. In females, initial diagnosis of AGW was most frequently made by a gynaecologist (71.7%, whereas in males, AGW were most frequently diagnosed by a dermatologist (44.8% or urologist (25.1%. Conclusions Incidence of AGW in Germany is comparable with findings for other countries. As expected, most cases occurred in the younger age groups. The frequency of diagnoses of AGW differs between sexes and women and men receive treatment by doctors of different specialties.

Report of the 8th International Symposium on the Observation of the Continental Crust Through Drilling; Dai 8 kai tairiku kagaku kussaku kokusai symposium ni sankashite

Energy Technology Data Exchange (ETDEWEB)

Yoshida, K. [Super Deep Core Drilling Study Group, Japan, Tokyo (Japan)

1996-11-29

This report relates to the 8th International Symposium on the Observation of the Continental Crust Through Drilling, convened at Agency of Industrial Science and Technology, Tsukuba City, on February 26, 1996. The symposium was represented by approximately 200 people from the U.S., Canada, Britain, Germany, France, Russia, China, and some others, who discussed active faults, drilling and logging, transfer of fluids and heat in the crust, history of the earth and climate, ICDP (International Continental Scientific Drilling Program) and international cooperation under this program in the future, etc. In reference to ultradeep drilling in the world, drillings by Germany`s KTB (Kontinentales Tiefbohrprogramm)(9,101m deep) and Russia at Kola Peninsula (l2,261m) were reviewed. Concerning the efforts of U.S. Continental Scientific Drilling Program during the previous 11-year period, it was reported that it had cost a total of $84,000,000; that investigations had been made into volcanos and geotherm, fault tectonics, sedimentary basins, holes due to meteorites, and metal ore deposits; and that 61 holes (total length: 31,310m and maximum depth: 3,510m) had been drilled and investigated. 6 figs., 3 tabs.

Synthetic Cu 0.507(5)Pb 8.73(9)Sb 8.15(8)I 1.6S 20.0(2) nanowires

Science.gov (United States)

Kryukova, Galina N.; Heuer, Matthias; Wagner, Gerald; Doering, Thomas; Bente, Klaus

2005-01-01

Nanowires of an iodine containing Pb-Sb-sulfosalt have been synthesized by chemical vapor transport. Their structure was studied using high-resolution transmission electron microscopy and X-ray powder diffraction. The lattice parameters show values equal to a=4.9801(4) nm, b=0.41132(8) nm (with two-fold superstructure), c=2.1989(1) nm and β=99.918(6)°. These parameters and the results of a multislice simulation are in good agreement with the mineral pillaite, Cu 0.10Pb 9.16Sb 9.84S 22.94Cl 1.06O 0.5 (space group C2/m, a=4.949(1) nm, b=0.41259(8) nm, c=2.1828(4) nm, and β=99.62(3)°). Microprobe and EDX analyses yielded a chemical composition of Cu 0.507(5)Pb 8.73(9)Sb 8.15(8)I 1.6S 20.0(2) which is close to natural pillaite but contains no oxygen and iodine instead of chlorine. The structure of the investigated material is based on chains of M-S polyhedra ( M=Pb or Sb) typical for the architecture of sulfosalts implying iodine atoms in trigonal prismatic coordination with Pb atoms from the M-S polyhedra of neighboring chains. The [010] superstructure of the specimen was found to be unstable under electron beam irradiation with a rapid decrease of the b lattice parameter from 0.8 to 0.4 nm within 5 min.

Synthetic Cu0.507(5)Pb8.73(9)Sb8.15(8)I1.6S20.0(2) nanowires

International Nuclear Information System (INIS)

Kryukova, Galina N.; Heuer, Matthias; Wagner, Gerald; Doering, Thomas; Bente, Klaus

2005-01-01

Nanowires of an iodine containing Pb-Sb-sulfosalt have been synthesized by chemical vapor transport. Their structure was studied using high-resolution transmission electron microscopy and X-ray powder diffraction. The lattice parameters show values equal to a=4.9801(4)nm, b=0.41132(8)nm (with two-fold superstructure), c=2.1989(1)nm and β=99.918(6) o . These parameters and the results of a multislice simulation are in good agreement with the mineral pillaite, Cu 0.10 Pb 9.16 Sb 9.84 S 22.94 Cl 1.06 O 0.5 (space group C2/m, a=4.949(1)nm, b=0.41259(8)nm, c=2.1828(4)nm, and β=99.62(3) o ). Microprobe and EDX analyses yielded a chemical composition of Cu 0.507(5) Pb 8.73(9) Sb 8.15(8) I 1.6 S 20.0(2) which is close to natural pillaite but contains no oxygen and iodine instead of chlorine. The structure of the investigated material is based on chains of M-S polyhedra (M=Pb or Sb) typical for the architecture of sulfosalts implying iodine atoms in trigonal prismatic coordination with Pb atoms from the M-S polyhedra of neighboring chains. The [010] superstructure of the specimen was found to be unstable under electron beam irradiation with a rapid decrease of the b lattice parameter from 0.8 to 0.4nm within 5min

Evaluation of the level of depression among medical students from Poland, Portugal and Germany.

Science.gov (United States)

Seweryn, Mariusz; Tyrała, Kinga; Kolarczyk-Haczyk, Aleksandra; Bonk, Magdalena; Bulska, Weronika; Krysta, Krzysztof

2015-09-01

Depression is a serious illness affecting health, family and professional life of many people of all sectors of society. It also concerns students, regardless of their geographical location. The Beck Depression Inventory (BDI) is a proper tool to brief check of the level of depression because it has high correlation with depression. The aim of this study was to assess and compare the level of depression among medical students from Poland, Portugal and Germany. Students from different countries were asked to fill in an electronic form containing the BDI. The form was created separately for each country, using official translation of the BDI, approved by the competent psychiatric association. Google Drive software was used for the electronic form, and Stat soft Statistica v10 software for statistical analysis. There were statistically significant differences (p<0.05) in terms of average score of the BDI and of the proportion of the scores more than 10 points of medical and technology students among kinds of studies and countries. The average score of the BDI of medical students: Poland: 13.76±9.99 points; Germany: 8.49±7.64 points; Portugal: 7.37±7.67 points. The average score of the BDI of technology students: Poland: 12.42±9.66 points; Germany: 10.51±8.49 points; Portugal: 9.25±8.97 points. The proportion of the scores more than 10 points of medical students: Poland 56.32% (285/506) Germany 34.92% (154/441) Portugal 26.03% (82/315). The proportion of the scores more than 10 points of technology students: Poland 55.01% (368/669) Germany 43.82% (156/356) Portugal 37.57% (136/362). The highest depression score among medical and technology students according the BDI was found in Poland. A proper monitoring of depression is required, as well as rapid and appropriate help for those who suffer from it.

Review of the flood risk management system in Germany after the major flood in 2013

Directory of Open Access Journals (Sweden)

Annegret H. Thieken

2016-06-01

Full Text Available Widespread flooding in June 2013 caused damage costs of €6 to 8 billion in Germany, and awoke many memories of the floods in August 2002, which resulted in total damage of €11.6 billion and hence was the most expensive natural hazard event in Germany up to now. The event of 2002 does, however, also mark a reorientation toward an integrated flood risk management system in Germany. Therefore, the flood of 2013 offered the opportunity to review how the measures that politics, administration, and civil society have implemented since 2002 helped to cope with the flood and what still needs to be done to achieve effective and more integrated flood risk management. The review highlights considerable improvements on many levels, in particular (1 an increased consideration of flood hazards in spatial planning and urban development, (2 comprehensive property-level mitigation and preparedness measures, (3 more effective flood warnings and improved coordination of disaster response, and (4 a more targeted maintenance of flood defense systems. In 2013, this led to more effective flood management and to a reduction of damage. Nevertheless, important aspects remain unclear and need to be clarified. This particularly holds for balanced and coordinated strategies for reducing and overcoming the impacts of flooding in large catchments, cross-border and interdisciplinary cooperation, the role of the general public in the different phases of flood risk management, as well as a transparent risk transfer system. Recurring flood events reveal that flood risk management is a continuous task. Hence, risk drivers, such as climate change, land-use changes, economic developments, or demographic change and the resultant risks must be investigated at regular intervals, and risk reduction strategies and processes must be reassessed as well as adapted and implemented in a dialogue with all stakeholders.

Uranium mining in Eastern Germany

International Nuclear Information System (INIS)

Sauer, H.D.

1990-01-01

A problem which simply does not exist in Western Germany is the uranium mining in the South of Eastern Germany (SDAG Wismuth). The cleaning up and control measure which are urgently needed will be a task for more than one generation. (orig./HP) [de

Nuclear energy in Germany

International Nuclear Information System (INIS)

1999-01-01

Since September 1998 the Federal Government formed by a Red/Green Coalition declared its goal: irreversible phase out of nuclear power plants. The first attempt to stop reprocessing as well as the first attempt to change nuclear law failed. The present situation is as follows: existing nuclear power plants operate in a most satisfying way producing 170 TWh/a. i.e. 35% of total production; transport license is not granted; no new NPP is planned, but Germany will participate in the French European Power Reactor (EPR) project. Concerning fast reactors, no industrial activities exist in Germany. There is no intention to build a facility, but Germany participates in the European CAPRA project. Existing research items are related to neutronics, safety analysis, irradiation experiment TRABANT, accelerator driven systems, thermohydraulics, safety

Probing the 8He ground state via the 8He(p,t)6He reaction

International Nuclear Information System (INIS)

Keeley, N.; Skaza, F.; Lapoux, V.; Alamanos, N.; Auger, F.; Beaumel, D.; Becheva, E.; Blumenfeld, Y.; Delaunay, F.; Drouart, A.; Gillibert, A.; Giot, L.; Kemper, K.W.; Nalpas, L.; Pakou, A.; Pollacco, E.C.; Raabe, R.; Roussel-Chomaz, P.; Rusek, K.; Scarpaci, J.-A.; Sida, J.-L.; Stepantsov, S.; Wolski, R.

2007-01-01

The weakly-bound 8 He nucleus exhibits a neutron halo or thick neutron skin and is generally considered to have an α+4n structure in its ground state, with the four valence neutrons each occupying 1p 3/2 states outside the α core. The 8 He(p,t) 6 He reaction is a sensitive probe of the ground state structure of 8 He, and we present a consistent analysis of new and existing data for this reaction at incident energies of 15.7 and 61.3A MeV, respectively. Our results are incompatible with the usual assumption of a pure (1p 3/2 ) 4 structure and suggest that other configurations such as (1p 3/2 ) 2 (1p 1/2 ) 2 may be present with significant probability in the ground state wave function of 8 He

Regional Variation of Chronic Kidney Disease in Germany: Results From Two Population-Based Surveys

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Nicole Aumann

2015-05-01

Full Text Available Background/Aims: Due to the increasing prevalence of risk factors for chronic kidney disease (CKD, kidney dysfunction becomes a major public health problem. We investigated the CKD prevalence and determined to what extent the variation of risk factors explains the different CKD prevalence in Germany. Methods: We analyzed data from 6,054 participants, aged 31 to 82 years, from the Study of Health in Pomerania (SHIP-1 in Northeast Germany and the Cooperative Health Research in the Region of Augsburg (KORA F4 Study in Southern Germany. Regional differences in selected percentiles corresponding to the cutpoints for estimated glomerular filtration rate (eGFR, 2 and albumin-to-creatinine ratio (ACR, ≥30 mg/g were tested using quantile regression models that adjusted for CKD risk factors. Results: The prevalence of decreased eGFRcreatinine-cystatinC (5.9 vs. 3.1 %, p creatinine-cystatinC and high ACR. Conclusions: The CKD prevalence is higher in Northeast than in Southern Germany. Differences in the prevalence of risk factors partly explain the higher disease burden of CKD in Northeast than in Southern Germany.

Alarming Proportions of Methicillin-Resistant Staphylococcus aureus (MRSA) in Wound Samples from Companion Animals, Germany 2010–2012

Science.gov (United States)

Vincze, Szilvia; Stamm, Ivonne; Kopp, Peter A.; Hermes, Julia; Adlhoch, Cornelia; Semmler, Torsten; Wieler, Lothar H.; Lübke-Becker, Antina; Walther, Birgit

2014-01-01

Staphylococcus (S.) aureus is an important cause of wound infections in companion animals, and infections with methicillin-resistant S. aureus (MRSA) are of particular concern due to limited treatment options and their zoonotic potential. However, comparable epidemiological data on MRSA infections in dogs, cats and horses is scarce, also limiting the knowledge about possible links to MRSA isolates from human populations. To gain more knowledge about the occurrence and genotypic variation of MRSA among wound swabs of companion animal origin in Germany we performed a survey (2010–2012) including 5,229 samples from 1,170 veterinary practices. S. aureus was identified in 201 (5.8%) canine, 140 (12.2%) feline and 138 (22.8%) equine swabs from a total of 3,479 canine, 1,146 feline and 604 equine wounds, respectively. High MRSA rates were identified with 62.7%, 46.4% and 41.3% in S. aureus of canine, feline and equine origin, respectively. Further genotyping including spa typing and multilocus sequence typing (MLST) revealed a comparable distribution of spa types among canine and feline MRSA with CC22 (47.6%; 49.2%) and CC5 (30.2%; 29.2%) as predominant lineages followed by CC398 (13.5%; 7.7%) and CC8 (4.0%; 9.2%). In contrast, the majority of equine MRSA belonged to CC398 (87.7%). Our data highlight the importance of S. aureus and MRSA as a cause of wound infections, particularly in cats and horses in Germany. While “human-associated” MRSA lineages were most common in dogs and cats, a remarkable number of CC398-MRSA was detected in horses, indicating a replacement of CC8-MRSA as the predominant lineage within horses in Germany. These data enforce further longitudinal epidemiological approaches to examine the diversity and temporal relatedness of MRSA populations in humans and animals to assess probable sources of MRSA infections. This would enable a sound risk assessment and establishment of intervention strategies to limit the additional spread of MRSA. PMID

Use of herbal medicinal products among children and adolescents in Germany

Science.gov (United States)

2014-01-01

Background Germany is a country with a high use of herbal medicinal products. Population-based data on the use of herbal medicinal products among children are lacking. The aim of this study is to investigate the prevalence, patterns and determinants of herbal medicine use among children and adolescents in Germany. Methods As data base served the German Health Interview and Examination Survey for Children and Adolescents (KiGGS), a representative population based survey conducted 2003–2006 by the Robert Koch Institute. 17,450 boys and girls aged 0–17 years provided information on drug use in the preceding seven days. Herbal medicinal products were defined according to the European and German drug laws. SPSS Complex Sample method was used to estimate prevalence rates and factors associated with herbal medicine use. Results The prevalence rate of herbal medicinal product use amounts to 5.8% (95% confidence interval 5.3-6.3%). Use of herbal medicine declines along with increasing age and shows no difference between boys and girls in younger age groups. Teenage girls are more likely to use herbal medicines than teenage boys. Two thirds of herbal medicines are used for the treatment of coughs and colds; nearly half of herbal medicines are prescribed by medical doctors. Determinants of herbal medicinal product use are younger age, residing in South Germany, having a poor health status, having no immigration background and coming from a higher social class family. Children’s and parents-related health behavior is not found to be associated with herbal medicine use after adjusting for social class. Conclusions Use of herbal medicinal products among children and adolescents between the ages of 0 and 17 years in Germany is widely spread and shows relatively higher rates compared to international data. This study provides a reference on the use of herbal medicinal products for policy-makers, health professionals and parents. Further studies are needed to investigate the

Energy R and D in Germany

Energy Technology Data Exchange (ETDEWEB)

Runci, PJ

1999-11-01

Germany's total national (i.e., combined public and private sector) funding for R&D stood at $42 billion in 1997. The private sector accounted for nearly 62% ($24 billion) of the total, while the public sector accounted for approximately 38%. Since the late 1970s, when the public and private sectors each funded roughly half of Germany's R&D, the private sector has steadily assumed a larger and larger role as the dominant supporter of R&D activity, while overall government funding has remained essentially flat for much of the past two decades. In addition to declining relative to private R&D expenditures, public R&D expenditures in Germany declined by 4% in real terms between 1991 and 1997, to approximately $15 billion. The reduction in R&D investments in the public sector can be attributed in large part to the financial challenges associated with German reunification and related shifts in social priorities including efforts to address high unemployment and to rebuild basic infrastructure in the eastern states. R&D expenditures have also declined as a percentage of the total public budget, from a peak of 3.4% in 1985 to 2.7% in 1996. Energy R&D has been the hardest hit of all major socioeconomic areas of R&D expenditure funded by the German government. Between 1981 and 1997, public energy R&D fell from approximately $1.6 billion to $400 million--a 75% real decline. The $850 million reduction in Germany's fission R&D budget (which constituted two-thirds of government R&D investment in 1985) explains some 90% of the funding decline. Negative public perceptions regarding the safety and environmental impacts of nuclear energy have reduced nuclear power's viability as a long-term energy option for Germany. Discussions of a complete nuclear phaseout are now under way. At the same time, the German government has slashed its investments in fossil energy R&D by more than 90%. While energy efficiency and renewable energy technologies have fared relatively well in comparison

Synthesis and antibacterial activity of insignin and its 8-methoxy- and 6-demethoxy derivatives

Directory of Open Access Journals (Sweden)

Aamer Saeed

2006-06-01

Full Text Available A short and efficient synthesis of insignin (8-hydroxy-6-methoxy-3-heptyl- isocoumarin (1, a metabolite of natural lichens, has been described. Reaction of 3,5-dimethoxyhomophthalic anhydride (2 with octanoyl chloride in the presence of 1,1,3,3-tetramethylguanidine (TMG and triethyl amine afforded the 6,8-dimethoxy-3-heptylisocoumarin (3 in high yield. Regioselective demethylation of the latter using anhydrous aluminum chloride furnished the 8-hydroxy-6-methoxy-3-heptylisocoumarin (1 whereas, the complete demethylation of (3 yielded 6,8-dihydroxy-3-heptylisocoumarin (4. The isocoumarins (1, 3, and 4 were examined in vitro for antibacterial activity and were shown to exhibit moderate activity.

The synthesis of 8-β-[(methylsulfinyl-[18O])-methyl]-6-propylergoline

International Nuclear Information System (INIS)

Wheeler, W.J.

1987-01-01

The synthesis of 18 O-labeled 8-Β-[(methylsulfinyl)-methyl]-6-propyl-ergoline(pergolide-[ 18 O]-sulfoxide) of undetermined stereochemistry by the reaction of 8-Β-(methylthiomethyl)-6-propyl-ergoline (pergolide) with bis-(4-methoxyphenyl)-selen-[ 18 O]-oxide in acetic acid is described. Although the yields were low and the incorporation of 18 O was not high, this procedure represents a convenient method for the preparation of 18 O-labeled sulfoxides of pergolide and other sulfides present in compounds for which the usual methods are inappropriate. (author)

The quaternary arsenide oxides Ce{sub 9}Au{sub 5-x}As{sub 8}O{sub 6} and Pr{sub 9}Au{sub 5-x}As{sub 8}O{sub 6}

Energy Technology Data Exchange (ETDEWEB)

Bartsch, Timo; Hoffmann, Rolf-Dieter; Poettgen, Rainer [Univ. Muenster (Germany). Inst. fuer Anorganische und Analytische Chemie

2016-07-01

The quaternary gold arsenide oxides Ce{sub 9}Au{sub 5-x}As{sub 8}O{sub 6} and Pr{sub 9}Au{sub 5-x}As{sub 8}O{sub 6} were synthesized from the rare earth elements (RE), rare earth oxides, arsenic and gold powder at maximum annealing temperatures of 1173 K. The structures were refined from single crystal X-ray diffractometer data: Pnnm, a=1321.64(6) pm, b=4073.0(3), c=423.96(2), wR2=0.0842, 3106 F{sup 2} values, 160 variables for Ce{sub 9}Au{sub 4.91(4)}As{sub 8}O{sub 6} and Pnnm, a=1315.01(4), b=4052.87(8), c=420.68(1) pm, wR2=0.0865, 5313 F{sup 2} values, 160 variables for Pr{sub 9}Au{sub 4.75(1)}As{sub 8}O{sub 6}. They represent a new structure type and show a further extension of pnictide oxide crystal chemistry. A complex polyanionic gold arsenide network [Au{sub 5}As{sub 8}]{sup 15-} (with some disorder in the gold substructure) is charge compensated with polycationic strands of condensed edge-sharing O rate at RE{sub 4/4} and O rate at RE{sub 4/3} tetrahedra ([RE{sub 4}O{sub 3}]{sub 2}{sup 12+}) as well as RE{sup 3+} cations in cavities.

[Current seroprevalence, vaccination and predictive value of liver enzymes for hepatitis B among refugees in Germany].

Science.gov (United States)

Hampel, Annika; Solbach, Philipp; Cornberg, Markus; Schmidt, Reinhold E; Behrens, Georg M N; Jablonka, Alexandra

2016-05-01

Currently only vague estimates exist for the seroprevalence and vaccination status for viral hepatitis B (HBV) in refugees arriving in Germany during the current refugee crisis. To assess the prevalence of hepatitis B in refugees arriving in northern Germany in 2015. In a cross-sectional study in 793 patients from all age groups tests for serological markers of hepatitis B virus infection (HBsAg, anti-HBc) and liver enzymes (ALT, AST, bilirubin, γGT, alkaline phosphatase) were performed in August 2015 at six reception centers in northern Germany. In 258 patients anti-HBs antibodies were assessed additionally. Of the tested refugees, 76.7 % were male, the median age was 28.8 ± 11.4 years, and 7.8 % were children under the age of 18. The overall prevalence of HBsAg and total anti-HBc was 2.3 % and 14.0 % respectively (2.5 % and 14.5 % in men; 1.2 % and 13.5 % in women). Prevalence was highest in 35 to 49-year-old patients for HBsAg (3.1 %) and for refugees over 50 years for anti-HBc (38 %). No immunity to Hepatitis B was found in 62 %, 18.6 % had been vaccinated against Hepatitis B, while 50 % of children aged up to 15 years (n = 12) had been vaccinated. Positive predictive values of elevated AST and ALT for detection of HBsAg was 0 and 0.016, respectively. Only two patients with a positive HBsAg had elevated transaminases. This study showed a high prevalence of HBsAg in a German refugee sample in comparison to the general German population. Liver enzymes are not an appropriate tool for screening for hepatitis B virus infection.

ARHGEF10 directs the localization of Rab8 to Rab6-positive executive vesicles.

Science.gov (United States)

Shibata, Satoshi; Kawanai, Tsubasa; Hara, Takayuki; Yamamoto, Asuka; Chaya, Taro; Tokuhara, Yasunori; Tsuji, Chinami; Sakai, Manabu; Tachibana, Taro; Inagaki, Shinobu

2016-10-01

The function of ARHGEF10, a known guanine nucleotide exchange factor (GEF) for RhoA with proposed roles in various diseases, is poorly understood. To understand the precise function of this protein, we raised a monoclonal antibody against ARHGEF10 and determined its localization in HeLa cells. ARHGEF10 was found to localize to vesicles containing Rab6 (of which there are three isoforms, Rab6a, Rab6b and Rab6c), Rab8 (of which there are two isoforms, Rab8a and Rab8b), and/or the secretion marker neuropeptide Y (NPY)-Venus in a Rab6-dependent manner. These vesicles were known to originate from the Golgi and contain secreted or membrane proteins. Ectopic expression of an N-terminal-truncated ARHGEF10 mutant led to the generation of large vesicle-like structures containing both Rab6 and Rab8. Additionally, small interfering (si)RNA-mediated knockdown of ARHGEF10 impaired the localization of Rab8 to these exocytotic vesicles. Furthermore, the invasiveness of MDA-MB231 cells was markedly decreased by knockdown of ARHGEF10, as well as of Rab8. From these results, we propose that ARHGEF10 acts in exocytosis and tumor invasion in a Rab8-dependent manner. © 2016. Published by The Company of Biologists Ltd.

West-East migration in Germany since 1990

OpenAIRE

Beck, Grit

2011-01-01

Not only did 2.5 million people migrate from East Germany to West Germany between 1991 and 2006, 1.5 million people also moved from West to East Germany. This counter-current movement took placed largely unnoticed by the public and researchers alike. This paper uses both quantitative and qualitative data to first of all examine how the population structure in the New Länder has changed as a result of interregional migration between Länder in East and West Germany. It goes on to study the moti...

8 CFR 207.6 - Control over approved refugee numbers.

Science.gov (United States)

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Control over approved refugee numbers. 207... ADMISSION OF REFUGEES § 207.6 Control over approved refugee numbers. Current numerical accounting of approved refugees is maintained for each special group designated by the President. As refugee status is...

Effect of Periodontal Therapy on Crevicular Fluid Interleukin-6 and Interleukin-8 Levels in Chronic Periodontitis

Directory of Open Access Journals (Sweden)

Paschalina Goutoudi

2012-01-01

Full Text Available Purpose. The aim of this study was to analyse the levels of interleukin-6 (IL-6 and interleukin-8 (IL-8 in gingival crevicular fluid (GCF of patients with chronic periodontitis prior to and following surgical and/or nonsurgical periodontal therapy for a period of 32 weeks. Methods. GCF samples were obtained from 24 nondiseased and 72 diseased sites of 12 periodontal patients prior to as well as at 6, 16, and 32 weeks following non-surgical and surgical periodontal therapy. IL-6 and IL-8 levels were determined by enzyme-linked immunosorbent assay (ELISA. Results. Periodontal treatment improved all clinical parameters. Both treatment modalities resulted in similar IL-6 as well as IL-8 levels. Mean IL-6 and IL-8 concentrations were significantly higher in non-diseased compared to diseased sites and increased significantly following treatment in diseased sites. Mean total amounts of IL-6 and IL-8 (TAIL-6, TAIL-8 did not differ significantly between diseased and nondiseased sites, while following therapy TAIL-8 levels decreased significantly. Conclusions. The data suggest that periodontal therapy reduced the levels of IL-8 in GCF. However, a strong relationship between IL-6, IL-8 amounts in GCF and periodontal destruction and inflammation was not found.

Effect of methyl substitution on optoelectronic properties of 1,3,6,8-tetraphenyl pyrenes

Directory of Open Access Journals (Sweden)

LIU Yanling

2014-06-01

Full Text Available Geometric structures of the ground states and excited states,frontier molecular orbitals,ionization potentials,electron affinities,reorganization energies,and absorption and emission spectra of three novel methyl-substituted 1,3,6,8-tetra-phenylpyrenes were studied theoretically by quantum-chemical methods,such as density functional theory (DFT.The results show that the position of methyl substituent on benzene ring has much effect on the optoelectronic properties of methyl-substituted 1,3,6,8-tetra-phenylpyrenes.Interestingly,the geometric structures and optoelectronic properties of the designed compound 1,3,6,8-tetra-p-tolylpyrene (TPPy are similar to those of 1,3,6,8-tetrakis(3,5-dimethylphenylpyrene (TDMPPy,which is worthy of being further researched.

[Quality of health care in Germany. A six-country comparison].

Science.gov (United States)

Sawicki, Peter T

2005-11-15

than patients in other countries to report that they did not have a clear understanding of the purpose of these medications. Further, German patients are more likely than those in other countries to report that their regular doctor rarely or never explains the possible side effects of their medications. 5. FAILURES IN HOSPITAL DISCHARGE PLANNING: Overall, hospitalized sicker adults in Germany face more failures in discharge management than in other countries. Of particular note is that Germany is less likely than all other countries to ensure that hospitalized patients have appointments for follow-up care upon discharge from hospital. 6. HOSPITAL-BASED INFECTIONS ARE RARE.: Hospitalized patients in Germany are less likely than in other surveyed countries to report that they developed an infection while in the hospital. 7. LAB NOTIFICATION DELAYS ARE INFREQUENT: Sicker adults in Germany are less likely than in other surveyed countries to report that they have experienced delays in being notified about abnormal lab test results. 8. GERMAN DOCTORS ARE LESS LIKELY TO INFORM PATIENTS ABOUT AN ERROR: When German patients experience medical and medication errors, they are less likely than are patients in other countries to be told by a doctor or other health care professional that an error had been made. 9. BETTER QUALITY OF CARE IN CHRONICALLY ILL PATIENTS: Generally , Germany is doing a better job than other countries at providing patients with chronic conditions some basic standards of preventive care. These patients are more likely to have a nurse in their doctor's office who is regularly involved in the management of their care. Patients from the old Bundeslaender seem to receive a better quality of diabetes care compared to those from the new Bundeslaender. 10. HAVING PRIVATE INSURANCE IS ASSOCIATED WITH INCREASED USE OF HEALTH CARE: German respondents who have private health insurance are more likely to see a specialist, to be hospitalized, and to have nonemergency

Farming for Health: Aspects from Germany

OpenAIRE

Neuberger, Konrad; Stephan, Ingrid; Hermanowski, Robert; Flake, Albrecht; Post, Franz-Joseph; van Elsen, Thomas

2006-01-01

Until now, the term ‘Farming for Health’ is unknown in Germany but it would cover a wide spectrum of different kinds of social agriculture already existing in Germany, such as farms that integrate disabled people or drug therapy into their farming system, or farms that integrate children, pupils or older people. Relevant work in Germany is done in ‘Sheltered Workshops’, where supporting and healing powers of farming and gardening are used for disabled people with a diversity of work possibili...

Humoral Immunity to AAV-6, 8, and 9 in Normal and Dystrophic Dogs

Science.gov (United States)

Shin, Jin-Hong; Yue, Yongping; Smith, Bruce

2012-01-01

Abstract Adeno-associated virus (AAV)-6, 8, and 9 are promising gene-delivery vectors for testing novel Duchenne muscular dystrophy gene therapy in the canine model. Humoral immunity greatly influences in vivo AAV transduction. However, neutralizing antibodies to AAV-6, 8, and 9 have not been systemically examined in normal and dystrophic dogs. To gain information on the seroprevalence of antibodies to AAV-6, 8, and 9, we measured neutralizing antibody titers using an in vitro transduction inhibition assay. We examined 72 naive serum samples and 26 serum samples obtained from dogs that had received AAV gene transfer. Our data demonstrated that AAV-6 neutralizing antibody was the most prevalent antibody in dogs irrespective of age, gender, disease status (dystrophic or not), and prior parvovirus vaccination history. Surprisingly, high-level anti-AAV-6 antibody was detected at birth in newborn puppies. Further, a robust antibody response was induced in affected, but not normal newborn dogs following systemic AAV gene transfer. Taken together, our data have provided an important baseline on the seroprevalence of AAV-6, 8, and 9 neutralizing antibodies in normal and Duchenne muscular dystrophy dogs. These results will help guide translational AAV gene-therapy studies in dog models of muscular dystrophy. PMID:22040468

Germany - an immigration country

OpenAIRE

Siebert, Horst

2003-01-01

Germany has about the same proportion of foreigners in its population as the United States, it is an immigration country. In a way, Germany has let immigration happen, but it did not really have an explicit immigration policy in the past. Now it has to make up its mind on its immigration policy in the future. The paper looks at the experience with immigration in the past, at the integration of foreigners and at the issues of immigration policy.

DIPYRIDOXYL(1,8-DIAMINO-3,6-DIOXAOCTANE) SCHIFF-BASE

African Journals Online (AJOL)

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KEY WORDS: Schiff base, N,N′-dipyridoxyl(1,8-diamino-3,6-dioxaoctane), DFT, B3LYP. INTRODUCTION. Schiff bases due to structural varieties and unique characteristics are the most versatile studied ligands in coordination chemistry [1, 2] and their metal complexes play an important role in the development of inorganic ...

44 CFR 6.8 - Subpoena and other legal demands.

Science.gov (United States)

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Subpoena and other legal..., DEPARTMENT OF HOMELAND SECURITY GENERAL IMPLEMENTATION OF THE PRIVACY ACT OF 1974 General § 6.8 Subpoena and other legal demands. Access to records in systems of records by subpoena or other legal process shall be...

Germany's socio-economic model and the Euro crisis

Directory of Open Access Journals (Sweden)

Michael Dauderstädt

2013-03-01

Full Text Available Germany's socio-economic model, the "social market economy", was established in West Germany after World War II and extended to the unified Germany in 1990. During a prolonged recession after the adoption of the Euro in 1998, major reforms (Agenda 2010 were introduced which many consider as the key of Germany's recent success. The reforms had mixed results: employment increased but has consisted to a large extent of precarious low-wage jobs. Growth depended on export surpluses based on an internal real devaluation (low unit labour costs which make Germany vulnerable to global recessions as in 2009. Overall inequality increased substantially.

Nudging Germany

DEFF Research Database (Denmark)

Purnhagen, Kai; Reisch, Lucia A.

Since 2015 behavioural scientists investigate at the German chancellery how one could regulate better. This piece illustrates the background of this new strategy and possible concequences for regulation and Rechtswissenschaft in Germany. We first discuss the concept of behaviourally informed regu...

Germany. A pioneer on earthen feet?

International Nuclear Information System (INIS)

Michaelowa, A.

2003-01-01

Germany is one of the two OECD countries having achieved substantial greenhouse gas reductions in the last decade. While a part was large reductions in industry after the economic crash in East Germany, a relevant share is due to the huge public infrastructure investments in East Germany. The real success of German climate policy in the past decade is the strong reduction of methane and nitrous oxide which has been almost unnoticed. German climate policy is a good example of how lobbying of interest groups leads to a complex maze of hundreds of measures whose effects are difficult to evaluate. Paradoxically, policies have focused on expensive measures and Germany clearly is a pioneer in the most expensive forms of renewable energy. Concerning cost-effective measures and market instruments, Germany is a laggard. Only slowly, policymakers start to notice this distortion and first, shaky steps towards a more cost-efficient policy are made. Several challenges such as nuclear phase-out and trends in household energy consumption will put pressure on government to embrace the Kyoto Mechanisms and to refocus domestic instruments well before the first commitment period

Thuringische builds large PET plant in Germany

International Nuclear Information System (INIS)

Alperowicz, N.

1993-01-01

East Germany fibers producer Thuringische Faser AG Schwarza (TFS; Rudolstadt) is entering the polyethylene terephthalate (PET) business. The company, owned by India's Dalmia Group (New Delhi), is building an 80,000-m.t./year PET granulate plant, one of the largest in Europe, for completion at the end of 1995. The product will be used to make PET bottles and film for food packaging. TFS will need to buy 70,000 m.t./year of purified terephthalic acid and 27,000 m.t./year of ethylene glycol to feed the new plant. When acquiring TFS, Dalmia's chairman, Sanjay Dalmia, pledged to invest DM150 million ($95.4 million) in the Germany firm and keep 1,200 of the 3,000 workers. John Brown Deutsche Engineering (Essen) has been awarded a contract covering engineering, know-how, and turnkey supply of the complete plant, and will share of the complete plant, and will share the work with Austrian associate, Voest John Brown Industrieanlagenbau (Linz). The company, which completed against Zimmer (Frankfurt), will use its own technology. TFS, with 1992 sales of DM120 million, has capacities to produce 20,000 m.t/year of viscose staple fiber, 18,000 m.t./year of nylon-6 filament yarn, and 6,300 m.t./year of textile-grade polyester granulate, which will be converted to produce bottle-grade PET

Status of wind energy in Germany

Energy Technology Data Exchange (ETDEWEB)

Gerdes, G.; Molly, J.P.; Rehfeldt, K. [Deutsches Windenergie-Institut, Wilhelmshaven (Germany)

1996-12-31

By the end of 1995 in total 3655 wind turbines (WT`s) were installed in Germany with a total capacity of 1,136 MW. In the year 1995 alone the WT installations grew by 1,070 units with 505 MW. About 40% of the 1995 installations were sold to inland states of Germany with their lower wind speed potential. This fast development occurred in parallel to continuously reduced local state and federal subsidies. The further development is based mainly on the guaranteed reimbursement due to the Electricity Feed Law. But since some time the electricity utilities fight back on all legal and political levels to get cancelled the unloved Electricity Feed Law and since two years the building construction law with the foreseen privilege for WT`s is discussed without any result. All these difficulties affect investors and credit giving banks in such a negative way, that the further annual increase in wind power installation for 1996 could be 10 to 20% less than in 1995. Many of the new commercial Megawatt WT`s have pitch control and variable rotor speed which cause better electrical power quality and lower life time loads. From statistical evaluations on technical data of WT`s a good overview of the further development is derived. 8 refs., 10 figs.

Kinetic studies on the carboxylation of 6-amino-penicillanic acid to 8-hydroxy-penillic acid

DEFF Research Database (Denmark)

Henriksen, Claus Maxel; Holm, SS; Schipper, D.

1997-01-01

The carboxylation in aqueous solution of 6-amino-penicillanic acid (6-APA) to 8-hydroxy-penillic acid (8-HPA) was studied at 25 degrees C and pH 6.5. During sparging with either a citrate buffer or a chemically defined cultivation medium containing 6-APA with mixtures of carbon dioxide and air (2.......7-41% (v/v) CO2), the kinetics for conversion of 6-APA was followed by HPLC. In the citrate buffer 6-APA was converted by two competitive reactions each following first order kinetics with respect to the concentration of 6-APA: 1. carboxylation into 8-HPA; and 2. slow conversion into an unknown compound....... Formation of the unknown compound was not observed in the cultivation medium. The carboxylation of 6-APA was also found to be first order with respect to the concentration of dissolved carbon dioxide. The rate constant for formation of 8-HPA did not differ significantly in the cultivation medium compared...

Job satisfaction of radiologists in Germany. Status quo; Berufszufriedenheit von Radiologen in Deutschland. Aktueller Stand

Energy Technology Data Exchange (ETDEWEB)

Beitzel, K.I.; Grosse, C.; Reiser, M.; Ertl-Wagner, B. [Klinikum der Univ. Muenchen LMU, Grosshadern (Germany). Inst. fuer Kliniksche Radiologie; Ertl, L. [Klinikum der Univ. Muenchen LMU, Grosshadern (Germany). Inst. fuer Neuroradiologie

2011-08-15

Purpose: The aim of this study was to identify and evaluate the work-related satisfaction of radiologists and its influencing factors in Germany. Materials and Methods: For this purpose an invitational letter for an online opinion survey was sent to all member physicians of the Deutsche Roentgengesellschaft in 2008. 1200 questionnaires were completed (response rate 21 %) and evaluated statistically. Results: 81.7 % of radiologists declared themselves as being 'very' or 'rather satisfied'. The level of satisfaction was largely independent of age, gender, status, salary or family status. It increased over the last 5 years for 37.5 % of participants and decreased for 24.8 %. Nevertheless, 72 % of respondents indicated that they would not choose to specialize in radiology again. The main reason given was the workload. 65.6 % deemed it to be 'considerably' or 'rather too high'. Concomitantly, more than 70 % of respondents indicated that the workload had increased 'a lot' or 'rather'. Further reasons for not wanting to select the radiological profession again were 'unfavorable working hours' and 'unsatisfactory career perspectives'. Conclusion: The job satisfaction of radiologists in Germany is generally very high in spite of the perception of an extensive and frequently increasing workload. The high workload was the dominant factor against a renewed selection of the field of radiology. These data have to be interpreted in light of the current lack of residents and trained radiologists in Germany to counteract the trend toward emigration. (orig.)

Unitary Supermultiplets of $OSp(8^{*}|4)$ and the $AdS_{7}/CFT_{6}$ Duality

CERN Document Server

Günaydin, M; Gunaydin, Murat; Takemae, Seiji

2000-01-01

We study the unitary supermultiplets of the N=4 d=7 anti-de Sitter (AdS_7) superalgebra OSp(8^*|4), with the even subalgebra SO(6,2) X USp(4), which is the symmetry superalgebra of M-theory on AdS_7 X S^4. We give a complete classification of the positive energy doubleton and massless supermultiplets of OSp(8^*|4) . The ultra-short doubleton supermultiplets do not have a Poincaré limit in AdS_7 and correspond to superconformal field theories on the boundary of AdS_7 which can be identified with d=6 Minkowski space. We show that the six dimensional Poincare mass operator vanishes identically for the doubleton representations. By going from the compact U(4) basis of SO^*(8)=SO(6,2) to the noncompact basis SU^*(4)XD (d=6 Lorentz group times dilatations) one can associate the positive (conformal) energy representations of SO^*(8) with conformal fields transforming covariantly under the Lorentz group in d=6. The oscillator method used for the construction of the unitary supermultiplets of OSp(8^*|4) can be given ...

Acetylation of the Cd8 Locus by KAT6A Determines Memory T Cell Diversity

Directory of Open Access Journals (Sweden)

Dane M. Newman

2016-09-01

Full Text Available How functionally diverse populations of pathogen-specific killer T cells are generated during an immune response remains unclear. Here, we propose that fine-tuning of CD8αβ co-receptor levels via histone acetylation plays a role in lineage fate. We show that lysine acetyltransferase 6A (KAT6A is responsible for maintaining permissive Cd8 gene transcription and enabling robust effector responses during infection. KAT6A-deficient CD8+ T cells downregulated surface CD8 co-receptor expression during clonal expansion, a finding linked to reduced Cd8α transcripts and histone-H3 lysine 9 acetylation of the Cd8 locus. Loss of CD8 expression in KAT6A-deficient T cells correlated with reduced TCR signaling intensity and accelerated contraction of the effector-like memory compartment, whereas the long-lived memory compartment appeared unaffected, a result phenocopied by the removal of the Cd8 E8I enhancer element. These findings suggest a direct role of CD8αβ co-receptor expression and histone acetylation in shaping functional diversity within the cytotoxic T cell pool.

Integrated solid waste management in Germany

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-07-01

This report covers Germany`s experience with integrated solid waste management programs. The municipal solid waste practices of four cities include practices and procedures that waste facility managers with local or state governments may consider for managing their own day-to-day operations.

Handling adaptation governance choices in Sweden, Germany, the UK and the Netherlands. Workpackage 6, Deliverable 6A. Knowledge for Climate, Theme 7 "The governance of Adaptation"

NARCIS (Netherlands)

Huitema, D.; Mees, H.L.P.; Termeer, K.; Storbjork, S.; Garrelts, H.; Grecksch, K.; Winges, M.; Rayner, T.

2012-01-01

This document presents an overview of climate adaptation policies in four countries: Sweden, Germany, the UK and the Netherlands. The present report presents a collection of the papers that were discussed during a workshop with the international partners under KfC theme 7 Governance. To

Thoughts about the future of nuclear power in Germany

International Nuclear Information System (INIS)

Popp, M.

2008-01-01

On November 6, 2007, the Kerntechnische Gesellschaft conferred its 30 th honorary membership upon Professor Dr. Manfred Popp. The new Honorary Member has a record of outstanding achievements in the interest of nuclear power in Germany. This commitment is also apparent from his professional career, which was devoted to this high technology with impressive scientific and technical knowledge and political acumen, perseverance and stamina. The KTG is most grateful to Professor Popp for accepting its honorary membership. The article includes a revised version of the lecture given by Professor Manfred Popp at the ceremony conferring honorary membership. The author discusses some thoughts about the future of nuclear power in Germany in the light of societal, political, technical and environmental aspects. The status and perspectives of this technology are considered also within the framework of international developments. (orig.)

CTC Sentinel. Volume 6, Issue 8, August 2013

Science.gov (United States)

2013-08-01

future. Syria,” CTC Sentinel 6:8 (2013). 16 For some interesting work on this issue, see Thomas Hegghammer, “Should I Stay or Should I Go? Explain- ing...the late 1980s and early 1 Arie Perliger, “Democracy in an Ongoing Conflict: The Politics of Defence in Israel,” in James Forest and Isaiah Wilson...people of Syria and Iran…will not Hates Most, U.S. or Iran?” Bloomberg, February 5, 2013. 24 Thomas Erdbrink, “Khamenei: Iran Will Back ‘Any Nations

Energy R and D in Germany; TOPICAL

International Nuclear Information System (INIS)

PJ Runci

1999-01-01

Germany's total national (i.e., combined public and private sector) funding for R and D stood at$42 billion in 1997. The private sector accounted for nearly 62% ($24 billion) of the total, while the public sector accounted for approximately 38%. Since the late 1970s, when the public and private sectors each funded roughly half of Germany's R and D, the private sector has steadily assumed a larger and larger role as the dominant supporter of R and D activity, while overall government funding has remained essentially flat for much of the past two decades. In addition to declining relative to private R and D expenditures, public R and D expenditures in Germany declined by 4% in real terms between 1991 and 1997, to approximately$15 billion. The reduction in R and D investments in the public sector can be attributed in large part to the financial challenges associated with German reunification and related shifts in social priorities including efforts to address high unemployment and to rebuild basic infrastructure in the eastern states. R and D expenditures have also declined as a percentage of the total public budget, from a peak of 3.4% in 1985 to 2.7% in 1996. Energy R and D has been the hardest hit of all major socioeconomic areas of R and D expenditure funded by the German government. Between 1981 and 1997, public energy R and D fell from approximately$1.6 billion to$400 million--a 75% real decline. The$850 million reduction in Germany's fission R and D budget (which constituted two-thirds of government R and D investment in 1985) explains some 90% of the funding decline. Negative public perceptions regarding the safety and environmental impacts of nuclear energy have reduced nuclear power's viability as a long-term energy option for Germany. Discussions of a complete nuclear phaseout are now under way. At the same time, the German government has slashed its investments in fossil energy R and D by more than 90%. While energy efficiency and renewable energy

Decay heat removal and heat transfer under normal and accident conditions in gas cooled reactors. Proceedings of a specialists meeting held in Juelich, Germany, 6-8 July 1992

Energy Technology Data Exchange (ETDEWEB)

1994-08-15

The meeting was convened by the International Atomic Energy Agency on the recommendation of the IAEA`s International Working Group on Gas Cooled Reactors. It was attended by participants from China, France, Germany, Japan, Poland, the Russian Federation, Switzerland, the United Kingdom and the United States of America. The meeting was chaired by Prof. Dr. K. Kugeler and Prof. Dr. E. Hicken, Directors of the Institute for Safety Research Technology of the KFA Research Center, and covered the following: Design and licensing requirements for gas cooled reactors; concepts for decay heat removal in modern gas cooled reactors; analytical methods for predictions of thermal response, accuracy of predictions; experimental data for validation of predictive methods - operational experience from gas cooled reactors and experimental data from test facilities. Refs, figs and tabs.

Germany after Federal elections

International Nuclear Information System (INIS)

Niedzballa, G.

2010-01-01

The political, economical and social situation in Germany after the election and attitude to nuclear energy are summarised. The Coalition agreement include: 1.Extension of the remaining lifetimes of the nuclear power plants (Nuclear Power considered as “Bridging technology”; Safety first; Skimming of additional profits) 2. No nuclear new builds in Germany 3. Approval and promotion (loan guarantees) of nuclear exports 4. Reversal of the moratorium regarding the exploration of Gorleben salt dome (Completion of the exploration; International Peer Review Group) 5.Further research regarding competence preservation and safety

Molecular assembly and magnetic dynamics of two novel Dy6 and Dy8 aggregates.

Science.gov (United States)

Guo, Yun-Nan; Chen, Xiao-Hua; Xue, Shufang; Tang, Jinkui

2012-04-02

Complexation of dysprosium(III) with the heterodonor chelating ligand o-vanillin picolinoylhydrazone (H(2)ovph) in the presence of a carbonato ligand affords two novel Dy(6) and Dy(8) clusters, namely, [Dy(6)(ovph)(4)(Hpvph)(2)Cl(4)(H(2)O)(2)(CO(3))(2)]·CH(3)OH·H(2)O·CH(3)CN (2) and [Dy(8)(ovph)(8)(CO(3))(4)(H(2)O)(8)]·12CH(3)CN·6H(2)O (3). Compound 2 is composed of three petals of the Dy(2) units linked by two carbonato ligands, forming a triangular prism arrangement, while compound 3 possesses an octanuclear core with an unprecedented tub conformation, in which Dy(ovph) fragments are attached to the sides of the carbonato core. The static and dynamic magnetic properties are reported and discussed. In the Dy(6) aggregate, three Dy(2) "skeletons", having been well preserved (see the scheme), contribute to the single-molecule-magnet behavior with a relatively slow tunneling rate, while the Dy(8) cluster only exhibits a rather small relaxation barrier.

Peculiarities in electronic properties of molybdenum ternary sulphides PbMo6S8

International Nuclear Information System (INIS)

Shevchenko, A.D.; Aleksandrov, O.V.; Drozdova, S.V.; Kalyuzhnaya, G.A.; Kiseleva, K.V.; Primachenko, V.F.; Shevchuk, N.V.; Yachmenev, V.E.

1982-01-01

Effect of technological parameters of PbMo 6 S 8 on its superconducting and structural properties has been studied. For the first time lattice instability was discovered from X-ray diffraction investigations of PbMo 6 S 8 in the temperature range from 4.2 to 300 K near 80 K. pleasured were temperature dependences of specific resistance rho(Tsub(c)+-300 K), magnetic susceptibility chi(sub(c)+-300 K) and specific heat Csub(p)(2+-300 K) of the PbMo 6 S 8 system. Combined analysis of experimental results obtained and literature data on inelastic neutron scattering at 4.2 and 300 K permitted for the first time, to calculate quantitatively photon thermal capacity and its anharmonic component, temperature dependence #betta#subH(T) of electron heat capacity coefficient, zonal density of electron states Nsub(BS)(Esub(F)) at the Fermi level and electron-phonon interaction constant lambda(T). It is discovered that rho(T), #betta#sub(H)(T) and lambda(T) dependences behave themselves anomalously near temperatures approximately 80 K where lattice instability takes place and high-field superconductivity in PbMo 6 S 8 results from a large value of Nsub(BS)(Esub(F))

Hydrostatic Compression of 2,4,6,8,10,12 hexanitrohexaaza isowurtzitane (CL20) Co Crystals

Science.gov (United States)

2016-12-01

ARL-TR-7901 ● DEC 2016 US Army Research Laboratory Hydrostatic Compression of 2,4,6,8,10,12- hexanitrohexaaza-isowurtzitane (CL20... Hydrostatic Compression of 2,4,6,8,10,12- hexanitrohexaaza-isowurtzitane (CL20) Co-Crystals by DeCarlos Taylor Weapons and Materials...Technical Report 3. DATES COVERED (From - To) October 2015–September 2016 4. TITLE AND SUBTITLE Hydrostatic Compression of 2,4,6,8,10,12

One-dimensional σ-models with N = 5, 6, 7, 8 off-shell supersymmetries

International Nuclear Information System (INIS)

Gonzales, M.; Toppan, F.; Rojas, M.

2008-12-01

We computed the actions for the 1D N = 5 σ-models with respect to the two inequivalent (2, 8, 6) multiplets. 4 supersymmetry generators are manifest, while the constraint originated by imposing the 5-th supersymmetry automatically induces a full N = 8 off-shell invariance. The resulting action coincides in the two cases and corresponds to a conformally flat 2D target satisfying a special geometry of rigid type. To obtain these results we developed a computational method (for Maple 11) which does not require the notion of superfields and is instead based on the nowadays available list of the inequivalent representations of the 1D N-extended supersymmetry. Its application to systematically analyze the σ-models off-shell invariant actions for the remaining N = 5, 6, 7, 8 (k, 8, 8 - k) multiplets, as well as for the N > 8 representations, only requires more cumbersome computations. (author)

6 CFR 29.8 - Disclosure of Protected Critical Infrastructure Information.

Science.gov (United States)

2010-01-01

... 6 Domestic Security 1 2010-01-01 2010-01-01 false Disclosure of Protected Critical Infrastructure... PROTECTED CRITICAL INFRASTRUCTURE INFORMATION § 29.8 Disclosure of Protected Critical Infrastructure... Infrastructure Protection, or either's designee may choose to provide or authorize access to PCII under one or...

Health-resource use and costs associated with fibromyalgia in France, Germany, and the United States

Science.gov (United States)

Knight, Tyler; Schaefer, Caroline; Chandran, Arthi; Zlateva, Gergana; Winkelmann, Andreas; Perrot, Serge

2013-01-01

Background Fibromyalgia (FM) is a chronic disorder characterized by widespread, persistent pain. Prospective and retrospective studies have demonstrated substantial health-care costs associated with FM in a number of countries. This study evaluated and compared health-resource use (HRU) and associated costs related to FM in routine clinical practice across the US, France, and Germany. Methods Two separate, cross-sectional, observational studies of subjects with FM were conducted: one in the US and one in France and Germany. HRU related to prescription medication, physician office visits, diagnostic tests, and hospitalizations was abstracted from chart review; patient out-of-pocket costs and lost productivity were collected via subject self-report. Costs were assigned to HRU based on standard algorithms. Direct and indirect costs were evaluated and compared by simple linear regression. Results A total of 442 subjects (203 US, 70 France, 169 Germany) with FM were analyzed. The mean (standard deviation) age in the US, France, and Germany was 47.9 (10.9), 51.2 (9.5), and 49.2 (9.8), respectively (P = 0.085). Most subjects were female (95% US, 83% France, 80% Germany) (P < 0.001). Adjusted annual direct costs per subject for FM were significantly higher in the US ($7087) than in France ($481, P < 0.001) or Germany ($2417, P < 0.001). Adjusted mean annual indirect costs per subject for FM were lower in the US ($6431) than in France ($8718) or Germany ($10,001), but represented a significant proportion of total costs in all countries. Conclusion The significant HRU and costs associated with FM in the US, France, and Germany documented in this study highlight the substantial global economic burden of FM. Indirect costs represented a significant proportion of the total costs, particularly in Europe. Comparisons between the three countries show differences in HRU, with significantly higher direct costs in the US compared with France and Germany. PMID:23637545

[Tularemia in Germany].

Science.gov (United States)

Kohlmann, R; Geis, G; Gatermann, S G

2014-07-01

The bacterium Francisella tularensis is known for more than 100 years by now as the etiological agent of the disease tularemia, a zoonotic infection with a worldwide distribution in the Northern Hemisphere. The prevalence of tularemia shows a wide geographic variation, being comparably infrequent in Germany. Tularemia can present itself with multiple clinical manifestations including ulceroglandular, glandular, oropharyngeal, oculoglandular, respiratory and typhoidal forms. Due to the low prevalence and the unspecific symptomatology, a rapid diagnosis and early start of an effective therapy are rarely obtained. Thus, in this article we summarize important aspects concerning etiology, ecology and routes of transmission, recent epidemiologic situation, clinical picture, diagnostics and treatment of tularemia, focusing on the situation in Germany. © Georg Thieme Verlag KG Stuttgart · New York.

Recent facts about photovoltaics in Germany

International Nuclear Information System (INIS)

Wirth, Harry

2015-01-01

Germany is leaving the age of fossil fuel behind. In building a sustainable energy future, photovoltaics is going to have an important role. The following summary consists of the most recent facts, figures and findings and shall assist in forming an overall assessment of the photovoltaic expansion in Germany.

Transport of radioactive waste in Germany - a survey

International Nuclear Information System (INIS)

Alter, U.

1995-01-01

The transport of radioactive waste is centralised and coordinated by the German Railway Company (Deutsche Bahn AG, DB) in Germany. The conditioning of radioactive waste is now centralised and carried out by the Gesellschaft fuer Nucklear Service (GNS). The Germany Railway Company, DB, is totally and exclusively responsible for the transport, the GNS is totally and exclusively responsible for the conditioning of radioactive waste. The German Railway Company transports all radioactive waste from nuclear power plants, conditioning facilities and the existing intermediate storage facilities in Germany. In 1992 nearly 177 shipments of radioactive waste were carried out, in 1991 the total amount was 179 shipments. A brief description of the transport procedures, the use of different waste packages for radioactive waste with negligible heat generation and the transport routes within Germany will be given. For this purpose the inspection authorities in Germany have used a new documentation system, a special computer program for waste flow tracking and quality assurance and compliance assurance, developed by the electrical power companies in Germany. (Author)

Acculturation and depressive symptoms among Turkish immigrants in Germany.

Science.gov (United States)

Morawa, Eva; Erim, Yesim

2014-09-12

The present study explores the impact of acculturation on depressive symptoms among Turkish immigrants in Germany, taking into account different dimensions of cultural orientation. A total of 471 patients from two selected samples (254 primary care patients and 217 outpatients of a psychosomatic department) participated. Levels of acculturation were measured as orientation towards culture of origin (CO), and orientation towards the host culture (HC). Acculturation strategies (integration, assimilation, separation, and marginalization) were also assessed as well as their association with depressive symptoms (BDI). Furthermore, gender- and migration-related differences in terms of acculturation and levels of depressive symptomatology were analyzed. Integration was the acculturation strategy associated with the lowest level of depressive symptoms (M = 14.6, SD = 11.9), while marginalization was associated with the highest (M = 23.5, SD = 14.7). Gender was not found to have a significant impact on acculturation but influenced depressive symptoms, with women (M = 21.8, SD = 13.3) reporting higher levels of depressive symptomatology than men (M = 15.1, SD = 14.0; p acculturation and mental health.

Fusarium Keratitis in Germany

Science.gov (United States)

Stasch, Serena; Kaerger, Kerstin; Hamprecht, Axel; Roth, Mathias; Cornely, Oliver A.; Geerling, Gerd; Mackenzie, Colin R.; Kurzai, Oliver; von Lilienfeld-Toal, Marie

2017-01-01

ABSTRACT Fusarium keratitis is a destructive eye infection that is difficult to treat and results in poor outcome. In tropical and subtropical areas, the infection is relatively common and associated with trauma or chronic eye diseases. However, in recent years, an increased incidence has been reported in temperate climate regions. At the German National Reference Center, we have observed a steady increase in case numbers since 2014. Here, we present the first German case series of eye infections with Fusarium species. We identified Fusarium isolates from the eye or eye-related material from 22 patients in 2014 and 2015. Thirteen isolates belonged to the Fusarium solani species complex (FSSC), 6 isolates belonged to the Fusarium oxysporum species complex (FOSC), and three isolates belonged to the Fusarium fujikuroi species complex (FFSC). FSSC was isolated in 13 of 15 (85%) definite infections and FOSC in 3 of 4 (75%) definite contaminations. Furthermore, diagnosis from contact lens swabs or a culture of contact lens solution turned out to be highly unreliable. FSSC isolates differed from FOSC and FFSC by a distinctly higher MIC for terbinafine. Outcome was often adverse, with 10 patients requiring keratoplasty or enucleation. The use of natamycin as the most effective agent against keratitis caused by filamentous fungi was rare in Germany, possibly due to restricted availability. Keratitis caused by Fusarium spp. (usually FSSC) appears to be a relevant clinical problem in Germany, with the use of contact lenses as the predominant risk factor. Its outcome is often adverse. PMID:28747368

The Use of Tobacco, E-Cigarettes, and Methods to Quit Smoking in Germany.

Science.gov (United States)

Kotz, Daniel; Böckmann, Melanie; Kastaun, Sabrina

2018-04-06

Current data on tobacco use are a necessary prerequisite for the study of the implementation of tobacco control measures in the general population. The German Study on Tobacco Use (Deutsche Befragung zum Rauchverhalten, DEBRA) provides previously lacking data on key indicators of smoking behavior and on the consumption of new products such as e-cigarettes. The continual acquisition and accumulation of data permits the analysis of trends and precise statistical evaluation. Data were obtained by repeated face-to-face interviews, at 2-month intervals, of representative samples of approximately 2000 persons across Germany aged 14 years and above. For this article, data from 12 273 persons that were acquired in 6 waves of the survey (June/July 2016 to April/May 2017) were aggregated and weighted. The one-year prevalence of current tobacco consumption was 28.3% (95% confidence interval: [27.5; 29.1]) in the overall survey population and 11.9% [8.9; 14.9] among persons under age 18. Higher tobacco consumption was correlated with lower educational attainment and lower income. 28.1% of the smokers had tried to quit smoking in the past year; the most commonly used method of quitting was e-cigarettes (9.1%). Brief physician advice or pharmacotherapy for smoking cessation were tried by 6.1% and 7.0%, respectively. 1.9% of the overall survey population but only 0.3% of persons who had never smoked were current consumers of e-cigarettes. Tobacco consumption is very high in Germany compared to other countries in Western and Northern Europe, and its distribution across the population is markedly uneven, with a heavy influence of socioeconomic status.

3,6-Dithiaoctane-1,8-dicarboxylic acid and its metal complexes

NARCIS (Netherlands)

Bellaart, A.C.; Verbeek, J.L.

1969-01-01

A soln. contg. 1.5 g 3,6-dithiaoctane-1,8-dicarboxylic acid (HL) in 20 ml H2O was treated with 1.8 g Ag2O for 20 min on a boiling water bath to give H[AgL2], m.p. 115-16 Deg (uncor.). A structure is proposed on the basis of ir spectral studies and elec. cond. measurements. H[CuL2] was similarly

Depression Disturbs Germany

Institute of Scientific and Technical Information of China (English)

2011-01-01

The suicide of Robert Enke,the goalkeeper of the Germany national football team who had battled depression for years,stunned the country and cast depression into the national spotlight as a disturbing disease.

Dimensional reduction of exceptional E6,E8 gauge groups and flavour chirality

International Nuclear Information System (INIS)

Koca, M.

1984-01-01

Ten-dimensional Yang - Mills gauge theories based on the exceptional groups E 6 and E 8 are reduced to four-dimensional flavour-chiral Yang - Mills - Higgs theories where the extra six dimensions are identified with the compact G 2 /SU(3) and SO(7)/SO(6) coset spaces. A ten-dimensional E 8 theory leads to three families of SU(5), one of which lies in the 144-dimensional representation of SO(10)

Thermal expansion studies of ThW2O8 and UWO6

International Nuclear Information System (INIS)

Keskar, Meera; Krishnan, K.; Sali, S.K.

2014-01-01

Thorium and uranium oxysalts with hexavalent cations of elements of VI th group of the periodic table are important from mineralogical, environmental and technological points of view. Several molybdates and tungstates of uranium and thorium are known to have similar structural and thermo-physical properties. Earlier, thermal expansion behavior of ThMo 2 O 8 and UMoO 6 were reported from our laboratory. In the present work, thermal expansion behavior of ThW 2 O 8 and UWO 6 studied under vacuum from ambient to 1000 and 800℃, respectively using high temperature X-ray diffraction (HTXRD) technique is reported

Synthesis of new dithiacobaltaborane clusters derived from arachno-6,8-S2B7H9

International Nuclear Information System (INIS)

Kang, S.O.; Sneddon, L.G.

1988-01-01

A series of air-stable dithiacobaltaborane clusters has been isolated from either the reaction of the arachno-S 2 B 7 H 8 - anion with cobalt chloride and pentamethylcyclopentadienide or the reaction of neutral arachno-6,8-S 2 B 7 H 9 with cobalt atoms and pentamethylcyclopentadiene. Thus, the reaction of arachno-S 2 B 7 H 8 - with CoCl 2 and C 5 (CH 3 ) 5 - in THF gave, as the major products, the triple-decker compound nido-4,6-η-C 5 (CH 3 ) 52 Co 2 -3,5-S 2 B 2 H 2 (I) and the 11-vertex cluster nido-8,10(η-C 5 (CH 3 ) 5 ) 2 Co 2 -7,9-S 2 B 7 H 7 (III). Also isolated in smaller amounts were a chloride derivative of I, nido-1-Cl-4,6-(η-C 5 (CH 3 ) 5 ) 2 Co 2 -3,5-S 2 B 2 H (II), two isomers of III, nido-3,10-(η-C 5 (CH 3 ) 5 ) 2 Co 2 -7,9-S 2 B 7 H 7 (IV) and nido-3,5-(η-C 5 (CH 3 ) 5 ) 2 Co 2 -7,9-S 2 B 7 H 7 (V), and the eight-boron cluster nido-8-(η-C 5 (CH 3 ) 5 )Co-7,9-S 2 B 8 H 8 (VI). Other trace products of the reaction included the six-boron clusters nido-5,8-(η-C 5 (CH 3 ) 5 ) 2 Co 2 -6,9-S 2 B 6 H 6 (VII) and arachno-7-(η-C 5 (CH 3 ) 5 )Co-6,8-S 2 B 6 H 8 (VIII). Compound III was found to isomerize at 250 degree C to IV, which could then be converted to V at 300 degree C. The reaction of cobalt atoms with arachno-6,8-S 2 B 7 H 9 in the presence of pentamethylcyclopentadiene gave VIII as the major product; however, a number of other clusters including I, V, VI, and [(η-C 5 (CH 3 ) 5 ) 2 Co] + [(SB 10 H 10 ) 2 Co] - were isolated in trace amounts. 16 references, 6 figures, 3 tables

Health-resource use and costs associated with fibromyalgia in France, Germany, and the United States

Directory of Open Access Journals (Sweden)

Chandran A

2013-04-01

Full Text Available Tyler Knight,1 Caroline Schaefer,1 Arthi Chandran,2 Gergana Zlateva,2 Andreas Winkelmann,3 Serge Perrot4 1Health Economics and Outcomes Research, Covance Market Access Services, Gaithersburg, MD, USA; 2Primary Care Health Economics and Outcomes Research, Pfizer Global Health Economics, New York, NY, USA; 3Department of Physical Medicine and Rehabilitation, University Hospital Munich, Munich, Germany; 4Service de Médecine Interne et Thérapeutique, Université Paris Descartes, Paris, France Background: Fibromyalgia (FM is a chronic disorder characterized by widespread, persistent pain. Prospective and retrospective studies have demonstrated substantial health-care costs associated with FM in a number of countries. This study evaluated and compared health-resource use (HRU and associated costs related to FM in routine clinical practice across the US, France, and Germany. Methods: Two separate, cross-sectional, observational studies of subjects with FM were conducted: one in the US and one in France and Germany. HRU related to prescription medication, physician office visits, diagnostic tests, and hospitalizations was abstracted from chart review; patient out-of-pocket costs and lost productivity were collected via subject self-report. Costs were assigned to HRU based on standard algorithms. Direct and indirect costs were evaluated and compared by simple linear regression. Results: A total of 442 subjects (203 US, 70 France, 169 Germany with FM were analyzed. The mean (standard deviation age in the US, France, and Germany was 47.9 (10.9, 51.2 (9.5, and 49.2 (9.8, respectively (P = 0.085. Most subjects were female (95% US, 83% France, 80% Germany (P < 0.001. Adjusted annual direct costs per subject for FM were significantly higher in the US ($7087 than in France ($481, P < 0.001 or Germany ($2417, P < 0.001. Adjusted mean annual indirect costs per subject for FM were lower in the US ($6431 than in France ($8718 or Germany ($10,001, but represented

Impact of Disease Management Programs on HbA1c Values in Type 2 Diabetes Patients in Germany.

Science.gov (United States)

Kostev, Karel; Rockel, Timo; Jacob, Louis

2017-01-01

The aim was to analyze the impact of disease management programs on HbA1c values in type 2 diabetes mellitus (T2DM) patients in Germany. This study included 9017 patients followed in disease management programs (DMPs) who started an antihyperglycemic treatment upon inclusion in a DMP. Standard care (SC) patients were included after individual matching (1:1) to DMP cases based on age, gender, physician (diabetologist versus nondiabetologist care), HbA1c values at baseline, and index year. The main outcome was the share of patients with HbA1c HbA1c level as a dependent variable and the potential predictor (DMP versus SC). The mean age was 64.3 years and 54.7% of the patients were men. The mean HbA1c level at baseline was equal to 8.7%. In diabetologist practices, 64.7% of DMP patients and 55.1% of SC patients had HbA1c levels HbA1c levels HbA1c levels HbA1c levels HbA1c levels lower than 7.5% or 6.5% after 6 months of therapy in both diabetologist and general care practices. The present study indicates that the enrollment of T2DM patients in DMPs has a positive impact on HbA1c values in Germany.

Development of CO2 emissions in Germany in 2015. Another blow to the achievement of objectives in 2020

International Nuclear Information System (INIS)

Ziesing, Hans-Joachim

2016-01-01

In 2015, the total CO 2 emissions increased slightly in Germany. Compared to last year they were around 0.6% (5 million tonnes) higher. Conversely, they are temperature-adjusted 0.7% (5 million tonnes) declined. The emissions of all greenhouse gases are expected in 2015 by around 0.8% (7 million tonnes) increased or temperature-adjusted by 0.3% (3 million tonnes) have decreased. Even considering the temperature-adjusted values of the 2020 the targeted destination path is clearly missed. To that the greenhouse gas emissions would have to fall at least by about 3% in the year, 2015. The climate policy action has thus become rather more urgent. [de

Conference on ground-mounted photovoltaic plants in France and in Germany

International Nuclear Information System (INIS)

Viertl, Cornelia; Argenlieu, Philippe d'; Masson, Gaetan; Schwan, Kurt; Thomas, Christophe; Hoffmann, Uta; Bohl, Johannes; Gossement, Arnaud; Jaclot, Emmanuel

2015-01-01

The French-German office for Renewable energies (OFAEnR) organised a conference on the future of ground-mounted photovoltaic plants both in France and Germany. In the framework of this French-German exchange of experience, about 130 participants debated about the present day and future regulatory framework and about the opportunities and challenges for projects financing and electricity resale. The different steps of plants realisation, from the planning to the site selection, the construction and the environmental issues were addressed as well. This document brings together the available presentations (slides) made during this event: 1 - Introduction of PV tendering within the context of a premium system (Cornelia Viertl); 2 - Ground-mounted solar plants - evolution of the Legal and Regulatory framework in France - New calls for tender (Philippe d'Argenlieu); 3 - Competitiveness of Utility-Scale PV (Gaetan Masson); 4 - Power production by ground-mounted PV systems for nearby industrial parks (Kurt Schwan); 5 - experience feedback of a direct selling operator and the future role of direct solar power selling (Christophe Thomas); 6 - Financing solar plants via crowd-funding - opportunities and challenges (Uta Hoffmann); 7 - The Planning and approval Process in Germany: Potential for Standardization and Optimization? (Johannes Bohl); 8 - Planning and approval Procedures in France: towards an harmonization between the different competent authorities and a reduction of the periods allowed for appeals? (Arnaud Gossement); 9 - EDF Energies Nouvelles: Solar plant of the Base of Toul-Rosieres. Decontamination and valorisation of polluted sites thanks to the construction of ground-mounted plants (Emmanuel Jaclot)

Structure and stability of M6N8 clusters (M = Si, Ge, Sn, Ti).

Science.gov (United States)

Davydova, Elena I; Timoshkin, Alexey Y; Frenking, Gernot

2010-06-10

The structures and stabilities of the M(6)N(8) clusters (M = Si, Ge, Sn, Ti) have been theoretically studied at DFT and ab initio levels of theory. Two new isomers have been considered: cage-like molecules and propeller-like molecules. It is shown that only for M = Si are both isomers true minima on the potential energy surface. The thermodynamics of the dissociation process (1/6)M(6)N(8) --> (1/3)M(3)N(4) is discussed. For each M(3)N(4) molecule, four structures with different multiplicity are considered. The thermodynamic analysis shows that independently of the multiplicity of M(3)N(4) nitrides all M(6)N(8) clusters are stable in the gas phase in a wide temperature range and could be potential intermediates in chemical vapor deposition of the nitride materials.

Further ATLAS tunes of PYTHIA6 and Pythia 8

CERN Document Server

The ATLAS collaboration

2011-01-01

We present the latest developments of the ATLAS MC generator tuning project for the Pythia family of event generators, including the C++ Pythia 8 code. The PYTHIA 6 tunes presented here complete the ``AUET2B'' set by addition of parton shower and multi-parton interaction model tunings with three next-to-leading order (NLO) PDFs in addition to the leading-order and MC-adapted PDFs previously presented. This note also presents systematic variation ``eigentunes'' for the parton shower configurations in the AMBT2B/AUET2B tune series. The Pythia 8 MPI tunes in this note have been constructed for six different PDFs, making use of a new $x$-dependent hadronic matter distribution model. MPI eigentunes are constructed for the PDFs intended for use in ATLAS bulk MC production.

Inhibitory potency of 8-methoxypsoralen on cytochrome P450 2A6 (CYP2A6 allelic variants CYP2A6 15, CYP2A6 16, CYP2A6 21 and CYP2A6 22: differential susceptibility due to different sequence locations of the mutations.

Directory of Open Access Journals (Sweden)

Kai Hung Tiong

Full Text Available Human cytochrome P450 2A6 (CYP2A6 is a highly polymorphic isoform of CYP2A subfamily. Our previous kinetic study on four CYP2A6 allelic variants (CYP2A6 15, CYP2A6 16, CYP2A6 21 and CYP2A6 22 have unveiled the functional significance of sequence mutations in these variants on coumarin 7-hydroxylation activity. In the present study, we further explored the ability of a typical CYP2A6 inhibitor, 8-methoxypsoralen (8-MOP, in inhibition of these alleles and we hypothesized that translational mutations in these variants are likely to give impact on 8-MOP inhibitory potency. The CYP2A6 variant and the wild type proteins were subjected to 8-MOP inhibition to yield IC50 values. In general, a similar trend of change in the IC50 and Km values was noted among the four mutants towards coumarin oxidation. With the exception of CYP2A6 16, differences in IC50 values were highly significant which implied compromised interaction of the mutants with 8-MOP. Molecular models of CYP2A6 were subsequently constructed and ligand-docking experiments were performed to rationalize experimental data. Our docking study has shown that mutations have induced enlargement of the active site volume in all mutants with the exception of CYP2A6 16. Furthermore, loss of hydrogen bond between 8-MOP and active site residue Asn297 was evidenced in all mutants. Our data indicate that the structural changes elicited by the sequence mutations could affect 8-MOP binding to yield differential enzymatic activities in the mutant CYP2A6 proteins.

36 CFR 6.8 - National Park Service solid waste responsibilities.

Science.gov (United States)

2010-07-01

..., DEPARTMENT OF THE INTERIOR SOLID WASTE DISPOSAL SITES IN UNITS OF THE NATIONAL PARK SYSTEM § 6.8 National Park Service solid waste responsibilities. (a) Beginning one year after January 23, 1995, a Superintendent will not permit or allow a person to dispose of solid waste at a National Park Service operated...

Supporting English Language Learners in Math Class, Grades 6-8

Science.gov (United States)

Melanese, Kathy; Chung, Luz; Forbes, Cheryl

2011-01-01

This new addition to Math Solutions "Supporting English Language Learners in Math Class series" offers a wealth of lessons and strategies for modifying grades 6-8 instruction. Section I presents an overview of teaching math to English learners: the research, the challenges, the linguistic demands of a math lesson, and specific strategies and…

The visual arts influence in Nazi Germany

Directory of Open Access Journals (Sweden)

Bie Yanan

2016-01-01

Full Text Available This article will discuss the influence of visual art in Nazi Germany from two parts of visual arts, which are political photography and poster propaganda, analyzing the unique social and historical stage of Nazi Germany. And it emphasizes the ideology of the Nazis, which in Nazi Germany inflamed the political sentiment of the masses and took the visual art as their important instrument of political propaganda, while Nazi party used visual art on anti-society and war which is worth warning and criticizing for later generation.

Market value-oriented gas pricing in Germany

International Nuclear Information System (INIS)

Eimermacher, T.

1996-01-01

In Germany, natural gas faces stiff competition from other types of energy. In many applications, natural gas is capable of replacing other fuels. In addition there is a growing gas-to-gas competition in some European countries, either through pipeline construction by a competitor as in Germany or by mandatory third-party access as in UK. Competition leads to market value-oriented energy pricing, which is particularly evident in Germany. For the consumer, this competitive situation ensures that natural gas can be obtained (and remains available in the long term) at competitive prices

Growth and Characterization of Organic Marine Dye Compound: 6-Amino-8α-methoxy-5-methyl-4,7-dioxo-1,1a, 2,4,7,8,8a,8b-octahydroazireno[2',3':3,4] pyrrolo[1,2-α]indol- 8-yl]methyl Carbamate

OpenAIRE

Jayandran, M.; Balasubramanian, V.

2011-01-01

Single crystals of 6-amino-8α-methoxy-5-methyl-4,7-dioxo-1,1a, 2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-α]indol-8-yl]methyl carbamate (Mitomycin), an organic marine dye material has been grown from solution by slow evaporation at ambient temperature. The growth of crystals has been carried out at various pH values and the growth was confirmed at pH 6. The chemical composition of the grown crystals was determined by the FTIR spectra. The crystalline nature and its various planes of...

Structuring effects of [Ln6O(OH)8(NO3)6(H2O)12]2+ entities

International Nuclear Information System (INIS)

Guillou, O.; Daiguebonne, C.; Calvez, G.; Le Dret, F.; Car, P.-E.

2008-01-01

In order to obtain highly porous lanthanide-based coordination polymers we are currently investigating reactions between [Ln 6 O(OH) 8 (NO 3 ) 6 (H 2 O) 12 ] 2+ di-cationic hexanuclear entities and sodium salts of benzene-poly-carboxylic acids. Two new coordination polymers obtained during this study are reported here. In both cases, the hexanuclear entity has been destroyed during the reaction. However the resulting compounds are original thanks to a structuring effect of the poly-metallic complex. The first compound of chemical formula [Y 2 (C 8 H 4 O 4 ) 3 (DMF)(H 2 O)],2DMF crystallizes in the monoclinic system, space group P121/n (n o 14) with a = 16.0975(3) A, b = 14.4605(3) A, c = 17.7197(4) A, β = 92.8504(9) o and Z = 4. The second compound of chemical formula Y 2 (NO 3 ) 2 (C 10 H 2 O 8 )(DMF) 4 crystallizes in the triclinic system, space group P-1 (n o 2) with a = 7.5312(3) A, b = 9.0288(3) A, c = 13.1144(6) A, α = 92.6008(14) o , β = 94.9180(14) o , γ = 112.1824(16) o and Z = 2. Both crystal structures are 2D. Both crystal structures are described and the original structural features are highlighted and related to a potential structuring effect of the hexanuclear precursor

Agro-environmental policies in Germany

International Nuclear Information System (INIS)

Frohberg, K.; Weingarten

1997-01-01

Agricultural activities always have impacts on the environment. Whereas soil erosion is a minor problem in Germany water pollution due to modern and intensive agriculture is of major concern. At first the paper discusses to what extent agriculture contributes to environmental pollution in Germany, in particular to the pollution of surface waters (as well as hydroelectric power constructions on the Danube) and groundwater by nutrients and pesticides. Agro-environmental policy in Germany is dominated by command-and-control-measures. Hence, in the second section, recent developments of the most important legal and institutional settings concerning water conservation policies are surveyed with special emphasis on the Federal Water Act and the Implementation of the Nitrate Directive into German legislation by the Fertilizer Ordinance. Thirdly, impacts of alternative water conservation policies are investigated using a regionalized agricultural sector model. Information obtained by this model analysis cover the development of N-balances, potential nitrate concentrations in the recharged groundwater, costs potentially effected by this and resulting agricultural incomes on the country level of the former Federal Republic Germany. The last section focuses on programs promoting environmentally sound farming practices, which gained increasing importance in the Common Agricultural Policy of the European Union in the last years. It is argued that this development will also continue in the future. (author)

EMI in Germany

DEFF Research Database (Denmark)

Weiss, Felix; Schindler, Steffen

2017-01-01

This article discusses effectively maintained inequality considering two different examples from the Germany education system: secondary school attainment and enrolment in highly ranked universities among freshmen. In our analyses of secondary school attainment, we investigate whether considering...

Incidence, time trends and regional variation of childhood leukaemia in Germany and Europe

International Nuclear Information System (INIS)

Kaatsch, P.; Mergenthaler, A.

2008-01-01

This paper presents data on the German and Europe-wide incidence, time trends and regional variations of childhood leukaemia. Data were provided by the German Childhood Cancer Registry (GCCR), a population-based cancer registry recording all cases of malignant diseases in children under 15 y of age residing in Germany and by the Automated Childhood Cancer Information System (ACCIS) co-ordinated at International Agency for Research on Cancer, Lyon, that combines and evaluates data from several European population-based cancer registries. The incidence of leukaemia (44.0 per million) has increased in Europe as well as in Germany in the last decades (0.6% annually on average). Germany shows no systematic aggregation of regions with low or high cancer incidence in terms of regional clustering. Incidence rates differ between European regions with the highest rates in Northern Europe (48.0 per million) and the lowest rates in Eastern Europe (39.1). Altogether, the results from ACCIS and the GCCR show good agreement. (authors)

How do patients with a Turkish background evaluate their medical care in Germany? An observational study in primary care

Directory of Open Access Journals (Sweden)

Goetz K

2015-11-01

Full Text Available Katja Goetz,1 Jessica Bungartz,2 Joachim Szecsenyi,1 Jost Steinhaeuser3 1Department of General Practice and Health Services Research, University of Heidelberg, Heidelberg, Germany; 2Praxis Medizin im Zentrum, München, Germany; 3Institute of Family Medicine, University Hospital Schleswig-Holstein, Lübeck, Germany Background: Patients’ evaluation of medical care is an essential dimension of quality of care and an important aspect of the feedback cycle for health care providers. The aim of this study was to document how patients with a Turkish background evaluate primary care in Germany and determine which aspects of care are associated with language abilities.Methods: The study was based on an observational design. Patients with a Turkish background from German primary care practices completed the EUROPEP (European Project on Patient Evaluation of General Practice Care questionnaire consisting of 23 items. Seventeen primary care practices were involved with either German (n=8 or Turkish (n=9 general practitioners (GPs.Results: A convenience sample of 472 patients with a Turkish background from 17 practices participated in the study (response rate 39.9%. Practices with a German GP had a lower response rate (19.6% than those with a Turkish GP (57.5%. Items evaluated the highest were “keeping data confidential” (73.4% and “quick services for urgent health problems” (69.9%. Subgroup analysis showed lower evaluation scores from patients with good or excellent German language abilities. Patients who consulted a Turkish GP had higher evaluation scores.Conclusion: The evaluation from patients with a Turkish background living in Germany with either Turkish or German GPs showed lower scores than patients in other studies in Europe using EUROPEP. However, our results had higher evaluation scores than those of Turkish patients evaluating GPs in Turkey. Therefore, different explanation models for these findings should be explored in future studies

Interleukin-6 and Interleukin-8 Levels Correlate With the Severity of Aplastic Anemia in Children.

Science.gov (United States)

Gupta, Vineeta; Kumar, Sushil; Sonowal, Rimjhim; Singh, Surya K

2017-04-01

The aim of this study was to evaluate the levels of interleukin (IL)-6 and IL-8 in patients with aplastic anemia and its correlation with severity of the disease. IL-6 and IL-8 levels were measured in 40 patients with aplastic anemia in the age group of 4 to 14 years. A total of 40 healthy children served as controls. Quantitative estimation of IL-6 and IL-8 was performed using a solid-phase sandwich ELISA kit. Results were presented as IL-6 and IL-8 concentrations in pg/mL. Patients received immunosuppressive therapy per the British Committee for Standards in Haematology Guidelines 2009. Mean age of the patients was 9.78±2.74 years. IL-6 level of patients was elevated compared with controls (193.48±352.3 vs. 4.58±3.39; Paplastic anemia (724.33±519.42), followed by severe aplastic anemia (80.51±66.28 pg/mL), and non-severe aplastic anemia (6.01±1.89). Differences were statistically significant. A similar trend was also observed for IL-8 levels, where the levels were 41.02±24.23, 11.34±8.0, and 1.67±0.71 for very severe aplastic anemia, severe aplastic anemia, and non-severe aplastic anemia, respectively. The differences were again statistically significant. IL levels were also correlated with the treatment outcome. Responders had lower levels compared with nonresponders, but the difference was not statistically significant (186.36±322.45 vs. 198.74±368.10). Levels of ILs decreased in responders, but were not comparable with that of controls 6 months after therapy. High levels of IL-6 and IL-8 were observed in children with aplastic anemia. Increased levels showed correlation with disease severity and therefore appear to play an important role in aplastic anemia. However, levels had no significant correlation with the treatment outcome.

[Socioeconomic Gradients in Dental Care Accessibility in Germany].

Science.gov (United States)

Leonhardt, Konrad Alexander; Hirsch, Christian

2017-03-17

The aim of this study was to determine whether dental care accessibility in Germany from 2002 to 2009 was linked to socioeconomic status (SES) or household net income (HHN). Analysis was based upon a nation-wide cross-sectional survey of German adults from 18 to 79 years (mean 49.1 years; 55% females) which was conducted by the "Bertelsmann Gesundheitsmonitor" from 2002-2009. Patients in Germany visit the dentist 2.4 times per year independently of the SES. Patients with higher income paid per income group 34 € (95%- KI: 6 €-63 €) more for their denture. People from the middle class had 1.28 (95% CI: 1.02-1.22), and people from the upper class had 1.86 (95%-CI: 1.58-2.18) as much dental coinsurance coverage as people from the lower class. The ability to pay for denture and obtain dental insurance coverage rose with higher SES or HHN. The rise of additional payments for dental services leads to discrepancies in dental health care. © Georg Thieme Verlag KG Stuttgart · New York.

Germany at CERN

CERN Multimedia

2005-01-01

From left to right: Maximilian Metzger, CERN's Secretary-General, Hermann Schunck, Director at the German Federal Ministry of Education and Research, and Robert Aymar, CERN's Director-General, talking to Wolfgang Holler from Butting, one of the companies at the "Germany at CERN" exhibition. Far right : Susanne-Corinna Langer-Greipl from BMBF, delegate to the CERN Finance Committee. For three days, CERN's Main Building was transformed into a showcase for German industry. Twenty-nine companies from sectors related to particle physics (electrical engineering, vacuum and low temperature technology, radiation protection, etc.) were here for the ninth "Germany at CERN" exhibition, organised by the German Federal Ministry of Education and Research (BMBF), which gave them the opportunity to meet scientists and administrators from the Laboratory. On 1 March the exhibition was visited by a German delegation headed by Dr Hermann Schunck, Director at BMBF.

Epizootic emergence of Usutu virus in wild and captive birds in Germany.

Directory of Open Access Journals (Sweden)

Norbert Becker

Full Text Available This study aimed to identify the causative agent of mass mortality in wild and captive birds in southwest Germany and to gather insights into the phylogenetic relationship and spatial distribution of the pathogen. Since June 2011, 223 dead birds were collected and tested for the presence of viral pathogens. Usutu virus (USUV RNA was detected by real-time RT-PCR in 86 birds representing 6 species. The virus was isolated in cell culture from the heart of 18 Blackbirds (Turdus merula. USUV-specific antigen was demonstrated by immunohistochemistry in brain, heart, liver, and lung of infected Blackbirds. The complete polyprotein coding sequence was obtained by deep sequencing of liver and spleen samples of a dead Blackbird from Mannheim (BH65/11-02-03. Phylogenetic analysis of the German USUV strain BH65/11-02-03 revealed a close relationship with strain Vienna that caused mass mortality among birds in Austria in 2001. Wild birds from lowland river valleys in southwest Germany were mainly affected by USUV, but also birds kept in aviaries. Our data suggest that after the initial detection of USUV in German mosquitoes in 2010, the virus spread in 2011 and caused epizootics among wild and captive birds in southwest Germany. The data also indicate an increased risk of USUV infections in humans in Germany.

ATLAS tunes of PYTHIA 6 and Pythia 8 for MC11

CERN Document Server

The ATLAS collaboration

2011-01-01

We present the latest developments of the ATLAS MC generator tuning project for the Pythia family of event generators, including the C++ Pythia 8 code for the first time. The PYTHIA 6 tunes presented here, titled AMBT2B and AUET2B and constructed for a variety of PDFs, constitute alternatives to the AMBT2/AUET2 tunes previously presented as a candidate for MC11 event simulation. They systematically differ from the AMBT2/AUET2 PYTHIA 6 tunes in the treatment of alpha_S, to address concerns with those tunes. Systematic tune variations are also presented. The Pythia 8 tunes have been constructed for two different PDFs, and are aimed at an optimal description of minimum bias, for use in pile-up simulation. PDF-sensitive effects are observed and discussed in the MPI tunings of both generators.

Characterization of tick-borne encephalitis (TBE) foci in Germany and Latvia (1997-2000).

Science.gov (United States)

Süss, Jochen; Schrader, Christina; Abel, Ulrich; Bormane, Antra; Duks, Arnis; Kalnina, Vaira

2002-06-01

methods, we have also tested the low risk areas in the Odenwald (840 nymphs, 160 adults) and in Rhineland-Palatinate (920 nymphs, 78 adults). Ticks were collected in those areas where most TBE cases were registered. The virus prevalence in the Odenwald was 0% in adults and 0.5% in nymphs, whereas in ticks from Rhineland-Palatinate we have not found any positive PCR signal. Sequence data of the PCR products have shown that all strains in Germany were closely related to the central European virus prototype Neudoerfl. In I. ricinus ticks, collected in Riga county, the following virus prevalence rates were found: in females 2.4%, in males 3.7%, and in all adults 3.0%, in nymphs 2.4% and in the I. ricinus tick population examined 2.8%. The virus prevalence in I. persulcatus, collected in the eastern parts of Latvia was 6% in females, 4% in males and 5% in all adults. All the PCR products were sequenced and a phylogenetic tree was constructed. Studies in natural foci of TBE in Latvia have shown that I. ricinus carried the central European virus subtype (prototype Neudoerfl) whereas in I. persulcatus two strains have been found, the central European virus subtype (prototype Neudoerfl) and the Siberian virus subtype (prototype Vasilchenko). Sequences of the Far Eastern subtype have not been detected yet.

Magnetism and superconductivity in Eu(Ho)Mo/sub 6/S/sub 8/

Energy Technology Data Exchange (ETDEWEB)

Capone, D.W. II; Lai Fook, M.S.; Guertin, R.P.; Hinks, D.G.; Dunlap, B.D.; Foner, S.; Abou-Aly, A.I.; Brooks, J.S.

1984-10-01

A variety of ambient and high pressure experimental results reveal the interplay between magnetism and superconductivity in Ho doped samples of the pressure induced superconductor, EuMo/sub 6/S/sub 8/. Ho concentrations up to 50 atomic percent of the rare earth ions were used. High resolution magnetic measurements are consistent with the crystalline electric field ground state for the Ho/sup 3 +/ ions being a magnetic doublet consisting largely of J/sub z/ = 18. The results of high pressure magnetization experiments reveal negligible effects of reduced lattice constant on the rare earth-rare earth interactions. Resistivity in a 10 atomic percent sample for P = 10 kbar shows the suppression of a P = 0 structural transition, metallic conductivity down to low temperatures, and finally superconductivity at 8 K. The upper critical field, H/sub c2/(T), for this sample was measured for P = 7, 10 and 12 kbar and showed strong reentrant behavior (dH/sub c2/(T)/dT > 0 as T ..-->.. 0 K). A minimum with field in the resistivity above H/sub c2/ was also observed at lowest temperatures. The H/sub c2/(T) data are compared with those of EuMo/sub 6/S/sub 8/ at high pressure, which shows positive curvature, and HoMo/sub 6/S/sub 8/, in which superconductivity is quenched by ferromagnetism at low temperatures. 14 references, 4 figures.

How immigrants adapt their smoking behaviour: comparative analysis among Turkish immigrants in Germany and the Netherlands.

Science.gov (United States)

Reiss, Katharina; Sauzet, Odile; Breckenkamp, Jürgen; Spallek, Jacob; Razum, Oliver

2014-08-14

Smoking behaviour among immigrants is assumed to converge to that of the host country's majority population with increasing duration of stay. We compared smoking prevalence among Turkish immigrants residing in two different countries (Germany (DE)/the Netherlands (NL)) between and within countries by time spent in Turkey and DE/NL. The German 2009 micro-census and the Dutch POLS database (national survey, 1997-2004) were analysed. An interaction variable with dichotomised length of stay (LOS) in Turkey (age: 0-17; 18+) and categorised LOS in the host country (immigration year: 1979 and earlier, 1980-1999, 2000-2009; the latter only for Germany) was generated. Age standardised smoking prevalences and sex-specific logistic regression models were calculated. 6,517 Turkish participants were identified in Germany, 2,106 in the Netherlands. Age-standardised smoking prevalences were higher among Turkish immigrants in the Netherlands compared to those in Germany: 62.3% vs. 53.1% (men/lower education); 30.6% vs. 23.0% (women/lower education). A similar trend was observed for the majority population of both countries. The chance of being a smoker was lower among Turkish men with short LOS in Turkey and middle LOS in Germany/the Netherlands compared to those with short LOS in Turkey and long LOS in Germany/the Netherlands (NL: OR = 0.57[95% CI = 0.36-0.89]; DE: OR = 0.73[95% CI = 0.56-0.95]). Contrary to that, the chance of being a smoker was higher among Turkish men with long LOS in Turkey and middle LOS in Germany/the Netherlands compared to those with long LOS in Turkey and long LOS in Germany/the Netherlands (NL: OR = 1.35[95% CI = 0.79-2.33]; DE: OR = 1.44[95% CI = 1.03-2.02]). The effects for Turkish women were similar, but smaller and often non-significant. Turkish immigrants adapt their smoking behaviour towards that of the Dutch/German majority population with increasing duration of stay. This was particularly obvious among those who left Turkey before the age of 18

Episodic weakness due to mitochondrial DNA MT-ATP6/8 mutations.

Science.gov (United States)

Auré, Karine; Dubourg, Odile; Jardel, Claude; Clarysse, Lucie; Sternberg, Damien; Fournier, Emmanuel; Laforêt, Pascal; Streichenberger, Nathalie; Petiot, Philippe; Gervais-Bernard, Hélène; Vial, Christophe; Bedat-Millet, Anne-Laure; Drouin-Garraud, Valérie; Bouillaud, Frédéric; Vandier, Christophe; Fontaine, Bertrand; Lombès, Anne

2013-11-19

To report that homoplasmic deleterious mutations in the mitochondrial DNA MT-ATP6/8 genes may be responsible for acute episodes of limb weakness mimicking periodic paralysis due to channelopathies and dramatically responding to acetazolamide. Mitochondrial DNA sequencing and restriction PCR, oxidative phosphorylation functional assays, reactive oxygen species metabolism, and patch-clamp technique in cultured skin fibroblasts. Occurrence of a typical MELAS (mitochondrial encephalopathy with lactic acidosis and stroke-like episodes) syndrome in a single member of a large pedigree with episodic weakness associated with a later-onset distal motor neuropathy led to the disclosure of 2 deleterious mitochondrial DNA mutations. The MT-ATP6 m.9185T>C p.Leu220Pro mutation, previously associated with Leigh syndrome, was present in all family members, while the MT-TL1 m.3271T>C mutation, a known cause of MELAS syndrome, was observed in the sole patient with MELAS presentation. Significant defect of complexes V and I as well as oxidative stress were observed in both primary fibroblasts and cybrid cells with 100% m.9185T>C mutation. Permanent plasma membrane depolarization and altered permeability to K(+) in fibroblasts provided a link with the paralysis episodes. Screening of 9 patients, based on their clinical phenotype, identified 4 patients with similar deleterious MT-ATP6 mutations (twice m.9185T>C and once m.9176T>C or m.8893T>C). A fifth patient presented with an original potentially deleterious MT-ATP8 mutation (m.8403T>C). All mutations were associated with almost-normal complex V activity but significant oxidative stress and permanent plasma membrane depolarization. Homoplasmic mutations in the MT-ATP6/8 genes may cause episodic weakness responding to acetazolamide treatment.

Is Germany a model for managers?

Science.gov (United States)

Wever, K S; Allen, C S

1992-01-01

Most American managers have a hard time making sense of Germany. The country has a fraction of the resources and less than one-third the population of the United States. Labor costs are substantially higher, paid vacations are at least three times as long, and strong unions are deeply involved at all levels of business, from the local plant to the corporate boardroom. Yet German companies manage to produce internationally competitive products in key manufacturing sectors, making Germany the greatest competitive threat to the United States after Japan. The seemingly paradoxical nature of the German economy typically evokes one of two diametrically opposed responses. The first is to celebrate the German economy as a "model" worth emulating--indeed, as the answer to declining U.S. competitiveness. The alternative, more skeptical response is to question Germany's staying power in a new, more competitive global economy. According to Kirsten Wever and Christopher Allen, the problem with both points of view is that they miss the forest for the trees. Observers are so preoccupied with praising--or blaming--individual components of the German economy that they fail to see the dynamic logic that ties these components together into a coherent system. In their review of recent research on the German business system, Wever and Allen argue that managers can learn an important lesson from Germany. In the global economy, competition isn't just between companies but between entire socioeconomic systems. Germany's ability to design a cohesive economic and social system that adapts continuously to changing requirements goes a long way toward explaining that country's competitive success.

Imported and travelling dogs as carriers of canine vector-borne pathogens in Germany

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Lorentz Susanne

2010-04-01

Full Text Available Abstract Background With the import of pets and pets taken abroad, arthropod-borne diseases have increased in frequency in German veterinary practices. This is reflected by 4,681 dogs that have been either travelled to or relocated from endemic areas to Germany. The case history of these dogs and the laboratory findings have been compared with samples collected from 331 dogs living in an endemic area in Portugal. The various pathogens and the seroprevalences were examined to determine the occurrence of, and thus infection risk, for vector-borne pathogens in popular travel destinations. Results 4,681 dogs were examined serological for Leishmania infantum, Babesia canis and Ehrlichia canis. Buffy coats were detected for Hepatozoon canis and blood samples were examined for microfilariae via the Knott's test. The samples were sent in from animal welfare organizations or private persons via veterinary clinics. Upon individual requests, dogs were additionally examined serological for Anaplasma phagocytophilum, Borrelia burgdorferi and Rickettsia conorii. Overall B. canis was the most prevalent pathogen detected by antibody titers (23.4%, followed by L. infantum (12.2% and E. canis (10.1%. Microfilariae were detected in 7.7% and H. canis in 2.7% of the examined dogs. In 332/1862 dogs A. phagocytophilum, in 64/212 B. burgdorferi and in 20/58 R. conorii was detected. Of the 4,681 dogs, in total 4,226 were imported to Germany from endemic areas. Eighty seven dogs joined their owners for a vacation abroad. In comparison to the laboratory data from Germany, we examined 331 dogs from Portugal. The prevalence of antibodies/pathogens we detected was: 62.8% to R. conorii, 58% to B. canis, 30.5% to A. phagocytophilum, 24.8% to E. canis, 21.1% to H. canis (via PCR, 9.1% to L. infantum and 5.3% to microfilariae. Conclusions The examination of 4,681 dogs living in Germany showed pathogens like L. infantum that are non-endemic in Germany. Furthermore, the German

GERMANY & TURKEY – A PARTNERSHIP PERSPECTIVE

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Bestenigar KARA

2015-04-01

Full Text Available The article shortly deals with economic and commercial relations between Turkey, that keeps close regulary economic, political and cultural relationship and Germany, which is one of six founding fathers of the European Union. The subject of article has been searched within the following framework: Measurement of commercial relations between export and import between, investment relations between Germany and Turkey, mutual distribution sector.

Mental health of Turkish women in Germany

DEFF Research Database (Denmark)

Bromand, Z; Temur-Erman, S; Yesil, R

2012-01-01

The purpose of the present study was to examine the protective and risk factors of mental distress among Turkish women living in Germany.......The purpose of the present study was to examine the protective and risk factors of mental distress among Turkish women living in Germany....

Library Consortia in Germany

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Werner Reinhardt

2001-07-01

Full Text Available Looking at the present situation in Germany consortia show a considerable variety of organizational forms. Only in the case of the Friedrich-Althoff-Consortium in Berlin-Brandenburg a corporate body with deed of partnership does exist. In other German states consortia have been formed which are represented by an individual library (e.g. Baden-Württemberg or by a central institution such as the Bayerische Staatsbibliothek in Bavaria or the Hochschulbibliothekszentrum NRW in North Rhine-Westphalia. Rarely contracts for nationwide consortia have been signed; resulting from an initiative of a professional society, the „Gesellschaft Deutscher Chemiker“, an agreement was reached allowing for the use of the Beilstein-Crossfire-database in participating universities all over Germany.

Comparison of IL-6, IL-8 Concentrations in H. pylori- and non-H. pylori-associated Gastritis

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Gontar Alamsyah Siregar

2014-12-01

Full Text Available BACKGROUND: Helicobacter pylori is a non-invasive microorganism causing intense gastric mucosal inflammatory and immune reaction. The gastric mucosal levels of the proinflammatory cytokines Interleukin 6 (IL-6 and IL-8 have been reported to be increased in H. pylori infection, but the serum levels in H. pylori infection is still controversial. The purpose of this study was to investigate the serum levels of IL-6 and IL-8 in H. pylori infection. METHODS: A cross sectional study was done on eighty consecutive gastritis patients admitted to endoscopy units at Adam Malik General Hospital and Permata Bunda Hospital, Medan, Indonesia from May-October 2014. Histopathology was performed for the diagnosis of gastritis. Rapid urease test for diagnosis of H. pylori infection. Serum samples were obtained to determine circulating IL-6 and IL-8. Univariate and bivariate analysis (independent t test were done. RESULTS: There were 41.25% patients infected with H. pylori. Circulatory IL-6 levels were significantly higher in H. pylori-infected patients compared to H. pylori negative, but there were no differences between serum levels of IL-8 in H. pylori positive and negative patients. CONCLUSIONS: The immune response to H. pylori promotes systemic inflammation, which was reflected in an increased level of serum IL-6. Serum levels of IL-8 were not significantly different between H. pylori positive and negative. KEYWORDS: Helicobacter pylori, gastritis, IL-6, IL-8, cytokine.

Synthesis and luminescent properties of Sr{sub 2}Gd{sub 6.8}Eu{sub 1.2}Si{sub 6(1−x)}P{sub 6x}O{sub 26} oxyapatites

Energy Technology Data Exchange (ETDEWEB)

Ishchenko, A.V., E-mail: a-v-i@mail.ru [Ural Federal University, 620002 Ekaterinburg (Russian Federation); Zuev, M.G. [Ural Federal University, 620002 Ekaterinburg (Russian Federation); Institute of Solid State Chemistry, Ural Branch of the Russian Academy of Sciences, 620990 Ekaterinburg (Russian Federation); Vasin, A.A. [Institute of Solid State Chemistry, Ural Branch of the Russian Academy of Sciences, 620990 Ekaterinburg (Russian Federation); Yagodin, V.V.; Viktorov, L.V.; Shulgin, B.V. [Ural Federal University, 620002 Ekaterinburg (Russian Federation)

2016-01-15

The solid solutions Sr{sub 2}Gd{sub 6.8}Eu{sub 1.2}Si{sub 6(1−x)}P{sub 6x}O{sub 26−δ} (where x=0–0.15 and δ is oxygen nonstoichiometry) were synthesized. The structural properties of the crystal lattice of the solid solutions and the peculiarities of Eu{sup 3+} and P{sup 5+} dopants substitution for matrix ions have been considered. The photo-, X-ray and pulsed cathode luminescence properties have been studied. It has been found that substitution of (SiO{sub 4}){sup 4−} by (PO{sub 4}){sup 3−} tetrahedron in Eu{sup 3+}-doped oxyapatites does not bring significant changes to bands structure Eu{sup 3+} in luminescence spectra under different excitation (UV, X-ray, pulse cathode beam). However, the increase of P{sup 5+} concentration in Sr{sub 2}Gd{sub 6.8}Eu{sub 1.2}Si{sub 6(1−x)}P{sub 6x}O{sub 26–δ} compounds leads to a decrease of integral intensity of Eu{sup 3+} luminescence bands due to local environment symmetry modifications and covalency degree changes. Two nonequivalent optical Eu{sup 3+} centers have been found. These compounds are of interest for efficient X-ray phosphors, display devices and LED engineering material creation. - Highlights: • The luminescence properties were studied upon UV, X-ray and pulse cathode beam. • P{sup 5+} doping of Sr{sub 2}Gd{sub 6.8}Eu{sub 1.2}Si{sub 6}O{sub 26} leads to luminescence intensity reduction. • At least two types of optical centers formed by Eu{sup 3+} ions were found. • The structural features of Sr{sub 2}Gd{sub 6.8}Eu{sub 1.2}Si{sub 6(1−x)}P{sub 6x}O{sub 26} were reported. • Partial replacement of Si by P does not change the Sr{sub 2}Gd{sub 6.8}Eu{sub 1.2}Si{sub 6}O{sub 26} structure.

Preparation of 14C-labeled 8,9-didehydro-6,8-dimethyl-2-methylthioergoline mesylate, a dopamine antagonist potentially useful in the treatment of schizophrenia

International Nuclear Information System (INIS)

Wheeler, W.J.

1988-01-01

We have prepared 14 C-labeled 8,9-didehydro-6,8-dimethyl-2-methyl-thioergoline mesylate (LY 170542), a dopamine antagonist potentially useful as an anti-psychotic. The 14 C-label was introduced via a novel application of the Wittig reaction on 1-(4'-toluene-sulfonyl)-8,9-didehydro-6-methyl-ergolin-8-one and subsequent reduction of 1-(4'-toluenesulfonyl)-17-[ 14 C]-lysergene by lithium/ammonia at -33 0 C. The 17-[ 14 C]-agroclavine thus prepared was converted into 17-[ 14 C]-LY 170542 by reaction with methanesulfenyl chloride/methanesulfonic acid. (author)

Radioactive waste interim storage in Germany

International Nuclear Information System (INIS)

2015-12-01

The short summary on the radioactive waste interim storage in Germany covers the following issues: importance of interim storage in the frame of radioactive waste management, responsibilities and regulations, waste forms, storage containers, transport of vitrified high-level radioactive wastes from the reprocessing plants, central interim storage facilities (Gorleben, Ahaus, Nord/Lubmin), local interim storage facilities at nuclear power plant sites, federal state collecting facilities, safety, radiation exposure in Germany.

Electricity prices differences between France and Germany

International Nuclear Information System (INIS)

Hensing, I.; Nolden, A.; Riechmann, Ch.; Schulz, W.

1998-01-01

High electricity prices in Germany especially as compared to France have played an important role in the electricity liberalization debate in Germany. The price differences can largely be explained by cost differences in electricity generation, the electricity grids, personnel cost and local taxes. Further analysis suggests that efficiency improvements upon market liberalization will only partly remove these price and cost differentials. Parts of the cost differentials are attributable to politically-motivated regulations and the (future) regulation of network functions. This implies that Germany can only expect to arrive at internationally comparable electricity prices if it advances with a reform of political and monopoly regulations alongside liberalizing electricity generation and trade. (author)

Quality of health care of atopic eczema in Germany: results of the national health care study AtopicHealth.

Science.gov (United States)

Langenbruch, A; Radtke, M; Franzke, N; Ring, J; Foelster-Holst, R; Augustin, M

2014-06-01

The successful treatment of atopic eczema (AE) should result in the improvement of both physical symptoms and patient's quality of life (QoL). This study was conducted using a sample of dermatologists throughout Germany. This is due to dermatologists being the main health care providers of AE. Obtaining reliable data on quality of care of AE from both the patient's and the physician's perspective. This cross-sectional study assessed: the individual clinical history; dermatology-specific QoL (DLQI); state of health (EQ-5d-VAS); treatments; burden caused by disease and treatment; patient-defined treatment benefit (PBI). Data from 1678 adult patients (60.5% female, mean age: 38.4 ± 15.9) were analysed. The most frequently used treatments during the last five years were emollients (90.4%) and topical corticosteroids (85.5%). In this study, 75.8% of the patients felt only moderately or not at all impaired by their treatment. The mean DLQI (0 = minimum-30 = maximum QoL impairment) was 8.5 ± 6.5. The EQ-5d-VAS (100 = best possible) was 63.6 ± 22.0 on average. 26.6% reported suffering 'often' or 'every night' from sleeplessness due to severe itching. Mean PBI was 2.4 ± 1.1 (4 = maximum benefit). This study provides first data on the health care of adults with AE in Germany at a national level and reveals the need for a more effective care. Whereas most patients consider their treatment-related burden as low, the daily burden of the disease seems to be high: one third reports sleeplessness due to itching which indicates insufficient therapeutic regimes in these cases. A better implementation of the German national guideline for AE and a systematic analysis of the difficulties causing its limited effects is needed. © 2013 The Authors Journal of the European Academy of Dermatology and Venereology © 2013 European Academy of Dermatology and Venereology.

Severe influenza cases in paediatric intensive care units in Germany during the pre-pandemic seasons 2005 to 2008

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Liese Johannes G

2011-08-01

Full Text Available Abstract Background Data on complications in children with seasonal influenza virus infection are limited. We initiated a nation-wide three-year surveillance of children who were admitted to a paediatric intensive care unit (PICU with severe seasonal influenza. Methods From October 2005 to July 2008, active surveillance was performed using an established reporting system for rare diseases (ESPED including all paediatric hospitals in Germany. Cases to be reported were hospitalized children Results Twenty severe influenza-associated cases were reported from 14 PICUs during three pre-pandemic influenza seasons (2005-2008. The median age of the patients (12 males/8 females was 7.5 years (range 0.1-15 years. None had received vaccination against influenza. In 14 (70% patients, the infection had been caused by influenza A and in five (25% by influenza B; in one child (5% the influenza type was not reported. Patients spent a median of 19 (IQR 12-38 days in the hospital and a median of 11 days (IQR 6-18 days in the PICU; 10 (50% needed mechanical ventilation. Most frequent diagnoses were influenza-associated pneumonia (60%, bronchitis/bronchiolitis (30%, encephalitis/encephalopathy (25%, secondary bacterial pneumonia (25%, and ARDS (25%. Eleven (55% children had chronic underlying medical conditions, including 8 (40% with chronic pulmonary diseases. Two influenza A- associated deaths were reported: i an 8-year old boy with pneumococcal encephalopathy following influenza infection died from cerebral edema, ii a 14-year-old boy with asthma bronchiale, cardiac malformation and Addison's disease died from cardiac and respiratory failure. For nine (45% patients, possibly permanent sequelae were reported (3 neurological, 3 pulmonary, 3 other sequelae. Conclusions Influenza-associated pneumonia and secondary bacterial infections are relevant complications of seasonal influenza in Germany. The incidence of severe influenza cases in PICUs was relatively low

An overview on importance, synthetic strategies and studies of 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane (HNIW

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J. Venkata Viswanath

2016-10-01

Full Text Available 2,4,6,8,10,12-Hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane (HNIW, commonly called as CL-20, is a high energy and high density material of keen interest to both commercial and scientific worlds due to its greater insensitivity (reduced sensitivity along with a positive high heat of formation, which is due to the azanitro groups attached to the skeleton of HNIW and its highly strained cage structure. It plays a remarkable role in modification and replacement of most of the propellant (gun and rocket preparations. In this report we present the comparative strategies involved in the syntheses of HNIW with respect to economical and environmental aspects. Various methods reported in the literature on the purification of the crude HNIW (α-HNIW to obtain ε-form of HNIW (high dense/more potential are consolidated. Understanding of the structure, morphology, energetics, thermal behavior and their modification to meet the applicability (decreased impact sensitivity determines the industrial application of HNIW. A compilation of the available literature on the aforementioned characteristic properties for obtaining a value added ε-HNIW is discussed here. This overview also reports the literature available on newer forms of HNIW including derivatives and cocrystals, which increase the performance of HNIW.

Serum levels of interleukin-6 and interleukin-8 as diagnostic markers of acute pyelonephritis in children

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Abolfazl Mahyar

2013-05-01

Full Text Available &lt;b&gt;Purpose:&lt;/b&gt; Early diagnosis and treatment of acute pyelonephritis in children is of special importance in order to prevent serious complications. This study was conducted to determine the diagnostic value of serum interleukin (IL-6 and IL-8 in children with acute pyelonephritis. &lt;b&gt;Methods:&lt;/b&gt; Eighty seven patients between 1 month to 12 years old with urinary tract infection (UTI were divided into 2 groups based on the result of 99m-technetium dimercapto-succinic acid (DMSA renal scan: acute pyelonephritis (n=37 and lower UTI (n=50 groups. White blood cell (WBC count, neutrophil (Neutl count, erythrocyte sedimentation rate (ESR, C-reactive protein (CRP concentration, platelet count, and serum IL-6 and IL-8 concentrations of both groups were measured and compared . &lt;b&gt;Results:&lt;/b&gt; There was a significant difference between two groups regarding WBC count, Neutl count, ESR, and CRP concentration (P&lt;0.05. In addition, the difference between the two groups regarding serum IL-6 and IL-8 concentrations was not significant (IL-6, 60 and 35.4 pg/mL and IL-8, 404 and 617 pg/mL, respectively. The sensitivity and specificity of serum IL-6 and IL-8 for diagnosis of acute pyelonephritis were 73%, 42% and 78%, 32%, respectively. Sensitivity, specificity, negative and positive predictive values of serum IL-6 and IL-8 were less than those of acute phase serum reactants such as CRP. &lt;b&gt;Conclusion:&lt;/b&gt; This study showed that there was no significant difference between acute pyelonephritis and lower UTI groups regarding serum IL-6 and IL-8 levels. Therefore, despite confirming results of previous studies, it seems that IL-6 and IL-8 are not suitable markers for differentiating between acute pyelonephritis and lower UTI.

8He-6He: a comparative study of electromagnetic fragmentation reactions

International Nuclear Information System (INIS)

Meister, M.; Richter A.; Schrieder, G.; Simon, H.; Markenroth, K.; Jonson, B.; Nyman, G.; Zhukov, M.V.

2001-11-01

Dissociation of a 227 MeV/u 8 He beam in a lead target has been studied in a kinematically complete experiment. The results are compared with similar data from the well-known halo nucleus 6 He. Coulomb-nuclear interference in the inelastic channel gives evidence for a I π = 1 - resonance in 8 He at E x =4.15 MeV. The deduced B(E1) value of 0.38±0.07 e 2 fm 2 indicates a uniform distribution of the four neutrons around the α particle core. (orig.)

Cost of diabetic foot in France, Spain, Italy, Germany and United Kingdom: A systematic review.

Science.gov (United States)

Tchero, Huidi; Kangambega, Pauline; Lin, Lucien; Mukisi-Mukaza, Martin; Brunet-Houdard, Solenne; Briatte, Christine; Retali, Gerald Reparate; Rusch, Emmanuel

2018-04-01

Cost estimates for diabetic foot are available for developed countries based on cost data for different years. This study aimed to provide a comparison of the cost of diabetic foot in E5 (France, Spain, Italy, Germany, and the United Kingdom) and its characteristics across different conditions. PubMed, Central and Embase databases were searched in February 2017 for English language publications. Bibliographies of relevant papers were also searched manually. Reviews and research papers from E5 regions reporting on cost of diabetic foot were included. Reported cost was converted to equivalent 2016 $ for comparison purposes. All the costs presented are mean cost per patient per year in 2016 $. Nine studies were included in the analysis. The total cost of amputation ranged from $ 15,046 in 2001 to $ 38,621 in 2005. The direct cost of amputation ranged from $ 13,842 in 2001 to $ 83,728 during 2005-2009. Indirect cost of amputation was more uniform, ranging from between $ 1,043 to $ 1,442. The direct cost of gangrene ranged from $ 3,352 in 2003 to $ 8,818 in Germany. Although, for the same year, 2003, the cost for Spain was almost double that for Germany. The total cost of an uninfected ulcer was $ 6,174 in 2002, but increased to $ 14,441 in 2005; for an infected ulcer the cost increased from $ 2,637 to $ 2,957. The different countries showed variations in the components used to calculate the cost of diabetic foot. The E5 incurs a heavy cost from diabetic foot and its complications. There is an unmet need for the identification of cost-cutting strategies, as diabetic foot costs more than major cardiac diseases. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Ag@Ag_8W_4O_1_6 nanoroasted rice beads with photocatalytic, antibacterial and anticancer activity

International Nuclear Information System (INIS)

Selvamani, Muthamizh; Krishnamoorthy, Giribabu; Ramadoss, Manigandan; Sivakumar, Praveen Kumar; Settu, Munusamy; Ranganathan, Suresh; Vengidusamy, Narayanan

2016-01-01

Increasing resistance of pathogens and cancer cell line towards antibiotics and anticancer agents has caused serious health problems in the past decades. Due to these problems in recent years, researchers have tried to combine nanotechnology with material science to have intrinsic antimicrobial and anticancer activity. The metals and metal oxides were investigated with respect to their antimicrobial and anticancer effects towards bacteria and cancer cell line. In the present work metal@metal tungstate (Ag@Ag_8W_4O_1_6 nanoroasted rice beads) is investigated for antibacterial activity against Escherichia coli and Staphylococcus aureus using Mueller-Hinton broth and the anticancer activity against B16F10 cell line was studied. Silver decorated silver tungstate (Ag@Ag_8W_4O_1_6) was synthesized by the microwave irradiation method using Cetyl Trimethyl Ammonium Bromide (CTAB). Ag@Ag_8W_4O_1_6 was characterized by using various spectroscopic techniques. The phase and crystalline nature were analyzed by using XRD. The morphological analysis was carried out using Field Emission Scanning Electron Microscopy (FE-SEM), and High Resolution Transmission Electron Microscopy (HR-TEM). Further, Fourier Transform Infrared Spectroscopy (FT-IR) and Raman spectral analysis were carried out in order to ascertain the presence of functional groups in Ag@Ag_8W_4O_1_6. The optical property was investigated using Diffuse Reflectance Ultraviolet–Visible Spectroscopy (DRS-UV–Vis) and the band gap was found to be 3.08 eV. Surface area of the synthesized Ag@Ag_8W_4O_1_6 wasanalyzed by BET analysis and Ag@Ag_8W_4O_1_6 was utilized for the degradation of organic dyes methylene blue and rhodamine B. The morphology of the Ag@Ag_8W_4O_1_6 resembles roasted rice beads with breath and length in nm range. The oxidation state of tungsten (W) and silver (Ag) was investigated using X-ray photoelectron spectroscopy (XPS). - Highlights: • Synthesis of Ag@Ag_8W_4O_1_6 nanoroasted rice beads using

Fe-solubility of Ni7S6 and Ni9S8: Thermodynamic analysis

International Nuclear Information System (INIS)

Waldner, P.

2011-01-01

Experimental data on phase equilibria have been used for thermodynamic analysis of the iron solubility of the nickel sulfides Ni 7 S 6 and Ni 9 S 8 . For both compounds, a two-sublattice approach within the framework of the compound energy formalism has been applied to perform Gibbs free energy modelling at 0.1 MPa total pressure consistently embedded in recent thermodynamic assessment studies of other iron-nickel-sulfides. The predicted maxima of iron solubility around 3 at% of Ni 7 S 6 and 5.5 at% of Ni 9 S 8 are confirmed by experimental data. The calculations of complex ternary phase relations with Fe-bearing Ni 7 S 6 and Ni 9 S 8 gain further improvement. The first internally consistent description of all thermodynamically stable phases known in the literature for the iron-nickel-sulfur system is completed.

IL-6 trans-Signaling-Dependent Rapid Development of Cytotoxic CD8+ T Cell Function

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Jan P. Böttcher

2014-09-01

Full Text Available Immune control of infections with viruses or intracellular bacteria relies on cytotoxic CD8+ T cells that use granzyme B (GzmB for elimination of infected cells. During inflammation, mature antigen-presenting dendritic cells instruct naive T cells within lymphoid organs to develop into effector T cells. Here, we report a mechanistically distinct and more rapid process of effector T cell development occurring within 18 hr. Such rapid acquisition of effector T cell function occurred through cross-presenting liver sinusoidal endothelial cells (LSECs in the absence of innate immune stimulation and known costimulatory signaling. Rather, interleukin-6 (IL-6 trans-signaling was required and sufficient for rapid induction of GzmB expression in CD8+ T cells. Such LSEC-stimulated GzmB-expressing CD8+ T cells further responded to inflammatory cytokines, eliciting increased and protracted effector functions. Our findings identify a role for IL-6 trans-signaling in rapid generation of effector function in CD8+ T cells that may be beneficial for vaccination strategies.

Energy policies in the European Union. Germany's ecological tax reform

International Nuclear Information System (INIS)

Welfens, P.J.J.; Jungmittag, A.; Meyer, B.; Jasinski, P.

2001-01-01

The chapters discuss the following aspects: 1. Energy policy as a strategic element of economic policy in dynamic open economies. 2. Phasing out nuclear energy and core elements of sustainable energy strategy. 3. Ecological tax reform: Theory, modified double dividend and international aspects. 4. The policy framework in Europe and Germany. 5. Optimal ecological tax reform: Options and recommendations for an EU-action plan. 6. Conclusions. (orig./CB)

Coercive Diplomacy: Otto von Bismarck and the Unification of Germany

Science.gov (United States)

2012-02-24

politician, he forged a German empire under Prussian leadership that was ultimately realized on January 18, 1871, when King William I was crowned Emperor...the same pressures. King Frederick William cowered in the face of conflict, ordered his military to cease fighting the revolutionaries, and agreed...parliamentary rule, and the dissolution of the Prussian state into Germany. “Bismarck made himself noteworthy by his 6 championship of Prussian superiority

Conference on support mechanisms evolution and renewable energies integration in France and in Germany markets

International Nuclear Information System (INIS)

Praetorius, Barbara; Cruciani, Michel; Schwarz, Virginie; Nabe, Christian; Mayer, Joerg; Vogel, Wolfram; Abegg, Janosch; Lioret, Sonia; Avedissian, Franck; Cosse, Julien; Woodhouse, Stephen; Bradbury, Simon; Mollard, Matthieu; Solal, Lucie; Nodari, Antonio

2015-01-01

The French-German office for Renewable energies (OFAEnR) organised a conference on the support mechanisms evolution and the renewable energies integration in France and in Germany markets. In the framework of this French-German exchange of experience, participants exchanged views on the current support mechanisms in both countries and on their forthcoming legal modifications. The legal framework of direct renewable energy selling in the German market and the impacts and challenges of this model were addressed as well. Technical aspects of auction sales of electricity were approached too and illustrated with experience feedbacks from direct selling operators. This document brings together the available presentations (slides) made during this event: 1 - Tenders for Renewable energy and the German Energiewende - Perspectives, challenges, debates (Barbara Praetorius); 2 - Promotion of energy from renewable sources - A short analysis of the French public policy 2000 -2014 (Michel Cruciani); 3 - Support schemes for renewables in France and their evolution as foreseen in the energy transition law (Virginie Schwarz); 4 - Direct electricity selling on the wholesale market: legal framework and perspective - a French-German comparison (Christian Nabe); 5 - Self-consumption and power purchase Business framework in Germany (Joerg Mayer); 6 - Successful Integration of Renewable energies in the Market: the Role of the Power exchange (Wolfram Vogel); 7 - Earn money and do good by marketing renewables (Janosch Abegg); 8 - Proposals for a new electricity market design (Sonia Lioret)

Research of H5N6 Treatment by Comparing with H6N1 and H10N8 by Using Decision Tree and Apriori Algorithm

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Kim Sunghyun

2016-01-01

Full Text Available Since 2003, 608 people in 15 countries have infected with human-infectious AI viruses and 359 of them died. Especially, in China, H6N1 and H10N8 viruses were wide-spread and a lot of people were infected and died. Recently, H5N6 virus emerged in China and the number of patients has been increasing gradually. Therefore, this research compared amino acid strain of Matrix Protein, Hemagglutinin, Neuraminidase and Nucleoprotein of H5N6, H6N1 and H10N8, by using Decision tree and Apriori Algorithm, to figure out their similarity and devise the treatment. In result, Matrix protein and Nucleoprotein sequences of H5N6 were similar with those of H6N1 and H10N8. Therefore, this research concluded that the treatment targeting those proteins of H6N1 and H10N8 will be also effective to H5N6.

Public funding for medical research in relation to the burden of disease caused by cardiovascular diseases and neoplasms in Germany.

Science.gov (United States)

Krone, Manuel; Dufner, Vera; Wagner, Martin; Gelbrich, Götz; Ertl, Georg; Heuschmann, Peter U

2018-04-13

Public funding for medical research in Germany is primarily provided by the German Research Foundation (DFG) and the Federal Ministry of Education and Research (BMBF). The aim of this study was to analyze the amount of national public funding for medical research on predominant causes of death in Germany, cardiovascular diseases and neoplasms, in relation to the burden of these diseases in Germany. Three evaluators categorized medical research projects funded by the DFG or BMBF between 2010 and 2012 into the categories "Diseases of the circulatory system" (with subgroups "Ischemic heart diseases", "Heart failure" and "Cerebrovascular diseases") and "Neoplasms". The total amount of public funding by the national agencies was analyzed in relation to the burden of disease for the respective disease condition. Information on national public funding for medical research of 2091 million euros was available; of those, 246.8 million euros (11.8%) were categorized being spent for research on "Neoplasms", 118.4 million euros (5.7%) for research on "Diseases of the circulatory system". This results in 362.08 euros per case of death, 16.58 euros per year of life lost (YLL) and 16.04 euros per disability-adjusted life year (DALY) for "Neoplasms" and in 113.44 euros per case of death, 8.05 euros per YLL and 7.17 euros per DALY for "Diseases of the circulatory system". In Germany, research on cardiovascular diseases receives a lower share of national public funding for medical research compared to oncological research. These results are comparable to other European countries.

Sp6 and Sp8 Transcription Factors Control AER Formation and Dorsal-Ventral Patterning in Limb Development

Science.gov (United States)

Haro, Endika; Delgado, Irene; Junco, Marisa; Yamada, Yoshihiko; Mansouri, Ahmed; Oberg, Kerby C.; Ros, Marian A.

2014-01-01

The formation and maintenance of the apical ectodermal ridge (AER) is critical for the outgrowth and patterning of the vertebrate limb. The induction of the AER is a complex process that relies on integrated interactions among the Fgf, Wnt, and Bmp signaling pathways that operate within the ectoderm and between the ectoderm and the mesoderm of the early limb bud. The transcription factors Sp6 and Sp8 are expressed in the limb ectoderm and AER during limb development. Sp6 mutant mice display a mild syndactyly phenotype while Sp8 mutants exhibit severe limb truncations. Both mutants show defects in AER maturation and in dorsal-ventral patterning. To gain further insights into the role Sp6 and Sp8 play in limb development, we have produced mice lacking both Sp6 and Sp8 activity in the limb ectoderm. Remarkably, the elimination or significant reduction in Sp6;Sp8 gene dosage leads to tetra-amelia; initial budding occurs, but neither Fgf8 nor En1 are activated. Mutants bearing a single functional allele of Sp8 (Sp6−/−;Sp8+/−) exhibit a split-hand/foot malformation phenotype with double dorsal digit tips probably due to an irregular and immature AER that is not maintained in the center of the bud and on the abnormal expansion of Wnt7a expression to the ventral ectoderm. Our data are compatible with Sp6 and Sp8 working together and in a dose-dependent manner as indispensable mediators of Wnt/βcatenin and Bmp signaling in the limb ectoderm. We suggest that the function of these factors links proximal-distal and dorsal-ventral patterning. PMID:25166858

MGMT, GATA6, CD81, DR4, and CASP8 gene promoter methylation in glioblastoma

Directory of Open Access Journals (Sweden)

Skiriute Daina

2012-06-01

Full Text Available Abstract Background Methylation of promoter region is the major mechanism affecting gene expression in tumors. Recent methylome studies of brain tumors revealed a list of new epigenetically modified genes. Our aim was to study promoter methylation of newly identified epigenetically silenced genes together with already known epigenetic markers and evaluate its separate and concomitant role in glioblastoma genesis and patient outcome. Methods The methylation status of MGMT, CD81, GATA6, DR4, and CASP8 in 76 patients with primary glioblastomas was investigated. Methylation-specific PCR reaction was performed using bisulfite treated DNA. Evaluating glioblastoma patient survival time after operation, patient data and gene methylation effect on survival was estimated using survival analysis. Results The overwhelming majority (97.3% of tumors were methylated in at least one of five genes tested. In glioblastoma specimens gene methylation was observed as follows: MGMT in 51.3%, GATA6 in 68.4%, CD81 in 46.1%, DR4 in 41.3% and CASP8 in 56.8% of tumors. Methylation of MGMT was associated with younger patient age (p CASP8 with older (p MGMT methylation was significantly more frequent event in patient group who survived longer than 36 months after operation (p CASP8 was more frequent in patients who survived shorter than 36 months (p MGMT, GATA6 and CASP8 as independent predictors for glioblastoma patient outcome (p MGMT and GATA6 were independent predictors for patient survival in younger patients’ group, while there were no significant associations observed in older patients’ group when adjusted for therapy. Conclusions High methylation frequency of tested genes shows heterogeneity of glioblastoma epigenome and the importance of MGMT, GATA6 and CASP8 genes methylation in glioblastoma patient outcome.

Synthesis and evaluation of a "6"8Ga labeled folic acid derivative for targeting folate receptors

International Nuclear Information System (INIS)

Jain, Akanksha; Mathur, Anupam; Pandey, Usha; Bhatt, Jyotsna; Mukherjee, Archana; Ram, Ramu; Sarma, Haladhar Dev; Dash, Ashutosh

2016-01-01

Present work evaluates the potential of a newly synthesized "6"8Ga-NOTA-folic acid conjugate for PET imaging of tumors over-expressing folate receptors (FRs). NOTA-folic acid conjugate was synthesized and characterized. It was radiolabeled with "6"8Ga in ≥ 95% radiolabeling yields. In vitro cell binding studies showed a maximum cell uptake of 1.7±0.4% per million KB cells which was completely blocked on addition of cold folic acid showing specificity towards the FRs. However, further studies in tumor xenografts are warranted in order to assess the potential of "6"8Ga-folic acid complex for imaging tumors over-expressing FRs. - Highlights: • NOTA-Bn-(3-aminopropyl) folic acid conjugate was synthesized and characterized by "1H-NMR, ESI-MS and HPLC analysis. • NOTA-folic acid conjugate radiolabeled with "6"8Ga in >95% yields and high serum stability (≥95%) upto 1 h. • In vitro studies in KB cells showed specificity of NOTA-Bn-(3-aminopropyl) folic acid. • A maximum cell uptake of 1.7±0.4% per million KB cells was observed for "6"8Ga-NOTA-folic acid.

Recollections of a jewish mathematician in Germany

CERN Document Server

2016-01-01

Abraham A. Fraenkel was a world-renowned mathematician in pre–Second World War Germany, whose work on set theory was fundamental to the development of modern mathematics. A friend of Albert Einstein, he knew many of the era’s acclaimed mathematicians personally. He moved to Israel (then Palestine under the British Mandate) in the early 1930s. In his autobiography Fraenkel describes his early years growing up as an Orthodox Jew in Germany and his development as a mathematician at the beginning of the twentieth century. This memoir, originally written in German in the 1960s, has now been translated into English, with an additional chapter covering the period from 1933 until his death in 1965 written by the editor, Jiska Cohen-Mansfield. Fraenkel describes the world of mathematics in Germany in the first half of the twentieth century, its origins and development, the systems influencing it, and its demise. He also paints a unique picture of the complex struggles within the world of Orthodox Jewry in Germany....

Quarterly Costs Of Transporting Brazilian Soybeans From The North And Northeastern Ports To Hamburg, Germany

Data.gov (United States)

Department of Agriculture — Quarterly total landed costs (truck and ocean) of shipping Brazilian soybeans through the ports of Santarém and São Luís to Hamburg, Germany. This is table 6 of the...

Orthotopic Liver Transplantation in Human-Immunodeficiency-Virus-Positive Patients in Germany

Directory of Open Access Journals (Sweden)

E. Anadol

2012-01-01

Full Text Available Objectives. This summary evaluates the outcomes of orthotopic liver transplantation (OLT of HIV-positive patients in Germany. Methods. Retrospective chart analysis of HIV-positive patients, who had been liver-transplanted in Germany between July 1997 and July 2011. Results. 38 transplantations were performed in 32 patients at 9 German transplant centres. The reasons for OLT were end-stage liver disease (ESLD and/or liver failure due to hepatitis C (HCV (=19, hepatitis B (HBV (=10, multiple viral infections of the liver (=2 and Budd-Chiari-Syndrome. In July 2011 19/32 (60% of the transplanted patients were still alive with a median survival of 61 months (IQR (interquartile range: 41–86 months. 6 patients had died in the early post-transplantation period from septicaemia (=4, primary graft dysfunction (=1, and intrathoracal hemorrhage (=1. Later on 7 patients had died from septicaemia (=2, delayed graft failure (=2, recurrent HCC (=2, and renal failure (=1. Recurrent HBV infection was efficiently prevented in 11/12 patients; HCV reinfection occurred in all patients and contributed considerably to the overall mortality. Conclusions. Overall OLT is a feasible approach in HIV-infected patients with acceptable survival rates in Germany. Reinfection with HCV still remains a major clinical challenge in HIV/HCV coinfection after OLT.

Development of brown coal mining in the Federal Republic of Germany

Energy Technology Data Exchange (ETDEWEB)

Tilmann, W

1985-01-01

The significance of brown coal mining in the Federal Republic of Germany for the development of opencast technology and the power industry is discussed with emphasis on mining in the Rhineland Area. In 1984, 126.7 mt of brown coal were produced in the Federal Republic of Germany. In the development of high-performance equipment it is essential that the efficiency of the bucket-wheel excavator is increased. Trains and conveyors are mainly used for mine transport in the Federal Republic of Germany. A high moral commitment is linked to land claims, recultivation and environmental issues on the part of brown coal mining. In 1984 the percentage share of brown coal supplied to the public power stations was 83.6%, corresponding to 105.9 mt. The installed capacity of all brown coal power stations amounted to 12,764 MW at the end of 1984, providing around one quarter of overall public power output. Charge coal for coal refining has become more important and the production of brown coal dust and brown coal coke has also increased. The share of brown coal in domestic primary energy production is currently around 24% of 151 mt hard-coal units or around 10% of 376.5 mt hard-coal units in terms of energy consumption. 12 references.

Energy policies of IEA countries: Germany 2007 review

Energy Technology Data Exchange (ETDEWEB)

NONE

2007-07-01

The IEA report takes an in-depth look at the energy challenges facing Germany, and through comparisons with good examples in other IEA countries, provides critiques and recommendations for policy improvements. The review guides the country towards a sustainable energy future. Few countries can have as great an impact on energy policy in Europe as Germany. Its large size and strategic location make it a critical component of the region's energy markets - as a result, sound energy policies and strong energy market design are a necessity. In these respects, Germany continues to make notable progress. The country has continued to reform its electricity and natural gas markets, set a timetable to phase out coal subsidies, is meeting key climate and environmental targets and is bringing energy, efficiency and environment to the top of the world agenda with its presidencies of both the G8 and European Union. The International Energy Agency (IEA) praises these efforts. Nevertheless, work remains to be done to further improve German energy policies and markets. The planned phase-out of nuclear power over the coming years would have major impacts on the country's energy mix, raising concerns about energy security, economic efficiency and environmental sustainability for the country and for Europe as a whole. Furthermore, though progress has been made, more needs to be done to set a truly level playing field for competition to develop in gas and electricity markets, which means effective unbundling of transport activities and a strongly empowered regulatory authority. Finally, the country's environmental policies, though helping meet ambitious goals, are expensive - and sometimes various policies work at cross-purposes. 22 figs., 27 tabs., 4 apps.

Emission reduction program in the unified Germany

International Nuclear Information System (INIS)

Kehr, M.; Emsperger, W.; Termuehlen, H.

1992-01-01

High population density and intense industrialization in both parts of Germany resulted in high specific power demands. The domestic availability of hard coal and lignite made coal-fired power plants the backbone of power generation in all of Germany. The unification of Germany has brought together two power generation systems with similar basic needs and concepts. However, forty years existence within different economic systems has resulted in a quite different status in regard to installed generating capacity, availability of various fuels and environmental standards. To bridge the existing gap in a relatively short time is a huge challenge for the utilities, the power generation and distribution industry as well as for the federal and state authorities

Checklist of earthworms (Oligochaeta: Lumbricidae) from Germany.

Science.gov (United States)

Lehmitz, Ricarda; Römbke, Jörg; Jänsch, Stephan; Krück, Stefanie; Beylich, Anneke; Graefe, Ulfert

2014-09-23

A checklist of the German earthworm fauna (Oligochaeta: Lumbricidae) is presented, including published data, data from reports, diploma- and PhD- theses as well as unpublished data from museum collections, research institutions and private persons. Overall, 16,000 datasets were analyzed to produce the first German checklist of Lumbricidae. The checklist comprises 46 earthworm species from 15 genera and provides ecological information, zoogeographical distribution type and information on the species distribution in Germany. Only one species, Lumbricus badensis Michaelsen, 1907, is endemic to Germany, whereas 41% are peregrine. As there are 14 species occurring exclusively in the southern or eastern part of Germany, the species numbers in German regions increase from north to south.

THE EXON 5, 6, 7, 8 OF P53 MUTATIONS IN ORAL SQUAMOUS CELLS CARCINOMA

Directory of Open Access Journals (Sweden)

Retno P Rahayu

2012-04-01

Full Text Available Genetic instability may underlie the etiology of multistep carcinogenesis. The altered p53 gene observed in tumors may represent the expression of such instability and may allow the accumulation of other gene alterations caused by multiple mechanism. p53 gene is the guardian of the genome, that is why we pay more attention to this gene. In this study, we evaluated the significance of p53 mutation in 55 patient with oral squamous carcinoma. Thirty among them underwent well-differentiated carcinoma, while the remaining 25 patients underwent poorly differentiated carcinoma. The mutations were detected by PCR-SSCP (Single strand Conformational Polymorphism analysis in the region between exon 5 and exon 8. The results indicated that the p53 mutation in exon 5 (40%, exon 6 (28%, exon 7 (24% and exon 8 (8% were associated with poorly differentiated carcinoma, whereas mutation in exon 5 (10%, exon 6 (30%, exon 7 (40% and exon 8 (20% were associated with well-differentiated carcinoma. These observations suggest that p53 mutation in exon 5, 6, and 7 have strong correlation with poorly differentiated in oral squamous carcinoma while well-differentiated level was related with mutation in exon 6,7 and 8.

Zinc(II PVC-based membrane sensor based on 5,6-benzo-4,7,13,16,21,24- hexaoxa-1,10-diazabicyclo[8,8,8]hexacos-5-ene

Directory of Open Access Journals (Sweden)

Zamani Hassan Ali

2006-01-01

Full Text Available The 5,6-benzo-4,7,13,16,21,24-hexaoxa-1,10-diazabicyclo[8,8,8]hexacos-5-ene (BHDE was used as an excellent ionophore in construction of a Zn(II PVC-based membrane sensor. The best performance was obtained with a membrane composition of 30% poly(vinyl chloride, 64.5% nitrobenzen (NB, 2.5% BHDE and 3% sodium tetraphenylborate (NaTPB. This sensor shows very good selectivity and sensitivity towards zinc ion over a wide variety of cations, including alkali, alkaline earth, transition and heavy metal ions. The sensor revealed a great enhancement in selectivity coefficients for zinc ions, in comparison to the previously reported zinc sensors. The proposed sensor exhibits a Nernstian behavior (with slope of 29.1 ? 0.4 mV per decade over a wide concentration range (1.0 10-6-1.0 10-1 mol L-1 with a detection limit of 6.3 x10-7 mol L-1 (41.2 ng mL-1. It shows relatively fast response time, in the whole concentration range (< 10s, and can be used for at least 10 weeks in a pH range of 2.8-7.3. The proposed sensor was successfully used in direct determination of zinc ions in wastewater of industrial zinc electroplating companies, and also as an indicator electrode in titration with EDTA.

Healthcare Costs Associated with an Adequate Intake of Sugars, Salt and Saturated Fat in Germany: A Health Econometrical Analysis.

Directory of Open Access Journals (Sweden)

Toni Meier

Full Text Available Non-communicable diseases (NCDs represent not only the major driver for quality-restricted and lost life years; NCDs and their related medical treatment costs also pose a substantial economic burden on healthcare and intra-generational tax distribution systems. The main objective of this study was therefore to quantify the economic burden of unbalanced nutrition in Germany--in particular the effects of an excessive consumption of fat, salt and sugar--and to examine different reduction scenarios on this basis. In this study, the avoidable direct cost savings in the German healthcare system attributable to an adequate intake of saturated fatty acids (SFA, salt and sugar (mono- & disaccharides, MDS were calculated. To this end, disease-specific healthcare cost data from the official Federal Health Monitoring for the years 2002-2008 and disease-related risk factors, obtained by thoroughly searching the literature, were used. A total of 22 clinical endpoints with 48 risk-outcome pairs were considered. Direct healthcare costs attributable to an unbalanced intake of fat, salt and sugar are calculated to be 16.8 billion EUR (CI95%: 6.3-24.1 billion EUR in the year 2008, which represents 7% (CI95% 2%-10% of the total treatment costs in Germany (254 billion EUR. This is equal to 205 EUR per person annually. The excessive consumption of sugar poses the highest burden, at 8.6 billion EUR (CI95%: 3.0-12.1; salt ranks 2nd at 5.3 billion EUR (CI95%: 3.2-7.3 and saturated fat ranks 3rd at 2.9 billion EUR (CI95%: 32 million-4.7 billion. Predicted direct healthcare cost savings by means of a balanced intake of sugars, salt and saturated fat are substantial. However, as this study solely considered direct medical treatment costs regarding an adequate consumption of fat, salt and sugars, the actual societal and economic gains, resulting both from direct and indirect cost savings, may easily exceed 16.8 billion EUR.

Healthcare Costs Associated with an Adequate Intake of Sugars, Salt and Saturated Fat in Germany: A Health Econometrical Analysis.

Science.gov (United States)

Meier, Toni; Senftleben, Karolin; Deumelandt, Peter; Christen, Olaf; Riedel, Katja; Langer, Martin

2015-01-01

Non-communicable diseases (NCDs) represent not only the major driver for quality-restricted and lost life years; NCDs and their related medical treatment costs also pose a substantial economic burden on healthcare and intra-generational tax distribution systems. The main objective of this study was therefore to quantify the economic burden of unbalanced nutrition in Germany--in particular the effects of an excessive consumption of fat, salt and sugar--and to examine different reduction scenarios on this basis. In this study, the avoidable direct cost savings in the German healthcare system attributable to an adequate intake of saturated fatty acids (SFA), salt and sugar (mono- & disaccharides, MDS) were calculated. To this end, disease-specific healthcare cost data from the official Federal Health Monitoring for the years 2002-2008 and disease-related risk factors, obtained by thoroughly searching the literature, were used. A total of 22 clinical endpoints with 48 risk-outcome pairs were considered. Direct healthcare costs attributable to an unbalanced intake of fat, salt and sugar are calculated to be 16.8 billion EUR (CI95%: 6.3-24.1 billion EUR) in the year 2008, which represents 7% (CI95% 2%-10%) of the total treatment costs in Germany (254 billion EUR). This is equal to 205 EUR per person annually. The excessive consumption of sugar poses the highest burden, at 8.6 billion EUR (CI95%: 3.0-12.1); salt ranks 2nd at 5.3 billion EUR (CI95%: 3.2-7.3) and saturated fat ranks 3rd at 2.9 billion EUR (CI95%: 32 million-4.7 billion). Predicted direct healthcare cost savings by means of a balanced intake of sugars, salt and saturated fat are substantial. However, as this study solely considered direct medical treatment costs regarding an adequate consumption of fat, salt and sugars, the actual societal and economic gains, resulting both from direct and indirect cost savings, may easily exceed 16.8 billion EUR.

Comparison of Biological Effectiveness of Carbon-Ion Beams in Japan and Germany

International Nuclear Information System (INIS)

Uzawa, Akiko; Ando, Koichi; Koike, Sachiko; Furusawa, Yoshiya; Matsumoto, Yoshitaka; Takai, Nobuhiko; Hirayama, Ryoichi; Watanabe, Masahiko; Scholz, Michael; Elsaesser, Thilo; Peschke, Peter

2009-01-01

Purpose: To compare the biological effectiveness of 290 MeV/amu carbon-ion beams in Chiba, Japan and in Darmstadt, Germany, given that different methods for beam delivery are used for each. Methods and Materials: Murine small intestine and human salivary gland tumor (HSG) cells exponentially growing in vitro were irradiated with 6-cm width of spread-out Bragg peaks (SOBPs) adjusted to achieve nearly identical beam depth-dose profiles at the Heavy-Ion Medical Accelerator in Chiba, and the SchwerIonen Synchrotron in Darmstadt. Cell kill efficiencies of carbon ions were measured by colony formation for HSG cells and jejunum crypts survival in mice. Cobalt-60 γ rays were used as the reference radiation. Isoeffective doses at given survivals were used for relative biological effectiveness (RBE) calculations and interinstitutional comparisons. Results: Isoeffective D 10 doses (mean ± standard deviation) of HSG cells ranged from 2.37 ± 0.14 Gy to 3.47 ± 0.19 Gy for Chiba and from 2.31 ± 0.11 Gy to 3.66 ± 0.17 Gy for Darmstadt. Isoeffective D 10 doses of gut crypts after single doses ranged from 8.25 ± 0.17 Gy to 10.32 ± 0.14 Gy for Chiba and from 8.27 ± 0.10 Gy to 10.27 ± 0.27 Gy for Darmstadt, whereas isoeffective D 30 doses after three fractionated doses were 9.89 ± 0.17 Gy through 13.70 ± 0.54 Gy and 10.14 ± 0.20 Gy through 13.30 ± 0.41 Gy for Chiba and Darmstadt, respectively. Overall difference of RBE between the two facilities was 0-5% or 3-7% for gut crypt survival or HSG cell kill, respectively. Conclusion: The carbon-ion beams at the National Institute of Radiological Sciences in Chiba, Japan and the Gesellschaft fuer Schwerionenforschung in Darmstadt, Germany are biologically identical after single and daily fractionated irradiation.

N,N′-Dipyridoxyl(1,8-diamino-3,6-dioxaoctane) Schiff-base

African Journals Online (AJOL)

The N,N′-dipyridoxyl(1,8-diamino-3,6-dioxaoctane) (=H2L) Schiff-base has been synthesized and characterized by IR, 1H NMR, mass spectrometry and elemental analysis. Its optimized geometry and theoretical vibrational frequencies have been computed using density functional theory (DFT) method via the B3LYP ...

Dengue Virus Transmission by Blood Stem Cell Donor after Travel to Sri Lanka; Germany, 2013

Centers for Disease Control (CDC) Podcasts

2014-09-22

Dr. Mike Miller reads an abridged version of the article, Dengue Virus Transmission by Blood Stem Cell Donor after Travel to Sri Lanka; Germany, 2013.  Created: 9/22/2014 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 10/8/2014.

Simulation of 6 1/8 inch rigid coaxial RF transmission line

International Nuclear Information System (INIS)

Soni, Atul; Pande, M.M.; Rao, M.K.V.; Handu, V.K.

2006-01-01

A radio frequency (RF) transmission line has been designed based upon rigid coaxial 6 1/8 , 50-ohm line for coupling the RF power from its source to 400 KeV radio frequency quadrupole (RFQ) accelerator. Simulation and analysis have been carried out to evaluate various RF parameters of the line. (author)

Technological Studies at Thomas Edison Middle School. Grades 6-7-8.

Science.gov (United States)

Foster, Patrick N.

This technology studies curriculum for grades 6-8 is a plan for each middle school student to experience technology education for approximately 60 days (1 trimester of a 180-day school year) in each grade. Section A provides definitions; structure or content for grade-level programs with science and technology unifiers (unifying curricular…

SAPHIRE 8 Volume 6 - Quality Assurance

Energy Technology Data Exchange (ETDEWEB)

C. L. Smith; R. Nims; K. J. Kvarfordt

2011-03-01

The Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) Version 8 is a software application developed for performing a complete probabilistic risk assessment using a personal computer running the Microsoft Windows™ operating system. SAPHIRE 8 is funded by the U.S. Nuclear Regulatory Commission (NRC). The role of the INL in this project is that of software developer and tester. This development takes place using formal software development procedures and is subject to quality assurance (QA) processes. The purpose of this document is to describe how the SAPHIRE software QA is performed for Version 8, what constitutes its parts, and limitations of those processes. In addition, this document describes the Independent Verification and Validation that was conducted for Version 8 as part of an overall QA process.

Shape coexistence from lifetime and branching-ratio measurements in "6"8","7"0Ni

International Nuclear Information System (INIS)

Crider, B. P.; Prokop, C. J.; Liddick, S. N.; Al-Shudifat, M.; Ayangeakaa, A. D.

2016-01-01

Shape coexistence near closed-shell nuclei, whereby states associated with deformed shapes appear at relatively low excitation energy alongside spherical ones, is indicative of the rapid change in structure that can occur with the addition or removal of a few protons or neutrons. Near "6"8Ni (Z=28, N=40), the identification of shape coexistence hinges on hitherto undetermined transition rates to and from low-energy 0+ states. In "6"8","7"0Ni, new lifetimes and branching ratios have been measured. These data enable quantitative descriptions of the 0+ states through the deduced transition rates and serve as sensitive probes for characterizing their nuclear wave functions. The results are compared to, and consistent with, large-scale shell-model calculations which predict shape coexistence. With the firm identification of this phenomenon near "6"8Ni, shape coexistence is now observed in all currently accessible regions of the nuclear chart with closed proton shells and mid-shell neutrons.

Federal Republic of Germany: family planning, family policy and demographic policy.

Science.gov (United States)

Zuhlke, W

1989-01-01

Decades of social change in West Germany and the emergence of an ideology that stresses individualism have altered dramatically procreative behavioral patterns. At present, West Germany is characterized by a low marriage rate (6.1/1000 in 1986), declining fertility (10.3 birth/1000), rising divorce rates (20.1/1000), and increases in the proportion of single-person households (34%). The relationship between family planning, family policy, and demographic policy is unclear and changing. Family planning practice is viewed as a part of comprehensive life planning and is based on factors such as partnership or marital status, sex roles, the conflict between working in the home and having a career, consumer aspirations, and housing conditions. The Government's family policy includes the following components: child benefits, tax relief on children, tax splitting arrangements for married couples, childcare allowance, parental leave, student grants, tax deductions for domiciliary professional help and nursing assistance, and the provision of daycare. Thus, West Germany's family policy is directed more at encouraging and facilitating parenthood and family life than at a setting demographic goals. There is no evidence, however, that such measures will be successful and divergent influences of other policy areas are often more compelling. Nor is there any way to quantify the fertility-costing impact of individual family policy measures. The indistinct nature of family planning policy in West Germany mirrors political differences between the current coalition government, which maintains a traditional view of the family, and the opposition Social-Democratic and Green Parties, which question whether the equality of men and women can be achieved in the context of old family structures.

Five strands of math drills big book : grades 6-8

CERN Document Server

Reed, Nat; Forest, Chris

2011-01-01

For grades 6-8, our Common Core State Standards-based resource meets the five strands of math concepts addressed by the NCTM standards and encourages the students to review the concepts in unique ways. Included are warm-up and timed drill activities which will push the boundaries of critical thought and demonstrate to students the importance of mathematical problems in Number & Operations, Geometry, Measurement, Data Analysis & Probability and Algebra using real world situations.

Undergraduate medical education in Germany

Directory of Open Access Journals (Sweden)

Chenot, Jean-François

2009-04-01

Full Text Available The purpose of this article is to give international readers an overview of the organisation, structure and curriculum, together with important advances and problems, of undergraduate medical education in Germany. Interest in medical education in Germany has been relatively low but has gained momentum with the new "Regulation of the Licensing of Doctors" which came into effect in 2003. Medical education had required substantial reform, particularly with respect to improving the links between theoretical and clinical teaching and the extension of interdisciplinary and topic-related instruction. It takes six years and three months to complete the curriculum and training is divided into three sections: basic science (2 years, clinical science (3 years and final clinical year. While the reorganisation of graduate medical education required by the new "Regulation of the Licensing of Doctors" has stimulated multiple excellent teaching projects, there is evidence that some of the stipulated changes have not been implemented. Indeed, whether the medical schools have complied with this regulation and its overall success remains to be assessed systematically. Mandatory external accreditation and periodic reaccreditation of medical faculties need to be established in Germany.

Chemical effects of (n, γ) nuclear reaction on (Mo6Cl8)Cl4

International Nuclear Information System (INIS)

Fucugauchi, L.A.; Millan, S.; Mondragon, A.; Solache-Rios, M.

1994-01-01

The chemical effects of 98 Mo(n, γ) 99 Mo reaction on molybdenum(II) chloride [(Mo 6 Cl 8 )Cl 4 ] have been studied. Retention, thermal and radiolytical annealing were determined. It was found that this molybdenum compound has low retention, a negligible tendency to thermal annealing and a virtual insensitivity to hydrolysis. For practical applications in the enrichment of 99 Mo by the Shilard-Chalmers method, molybdenum(II) chloride [(Mo 6 Cl 8 )Cl 4 ] appears to offer good prospects. (author) 14 refs.; 2 figs

Energy efficiency - Germany's most important energy source with an elevated potential of marketing. Lectrures; Energieeffizienz - Deutschlands wichtigste Energiequelle mit hohem Marketingpotenzial. Vortraege

Energy Technology Data Exchange (ETDEWEB)

NONE

2007-07-01

At the ICG Conference of the Innovation Congress GmbH (Cologne, Federal Republic of Germany), held at the Hotel Centrovital, Berlin (Federal Republic of Germany) on 31 May and 1 June 2007, the following lectures were held: (1) Energy efficiency at the European level (DG TREN, Brussels, Belgium); (2) Energy efficiency as a ''highlight'' of the German EU and G8 presidency - The action plans ''Energy efficiency'' from Brussels and Berlin (F. Schafhausen); (3) Potentials of energy efficiency - Industrial customers are targeted (H. Bradtke); (4) Energy Agencies as a partner for projects of energy efficiency (N. Huettenhoelscher); (5) Energy efficiency in practice - concepts and campaigns (S. Kohler); (6) Failure of the politics in the energy efficiency - the consumer is footing the bill. (H. Krawinkel); (7) The capital goods industry as an offerer of energy efficient technology (M.F. Zelinger); (8) Customer orientation and energy efficiency in focus (J. Hogrefe); (9) Energy efficiency measures as a new area of business for public utilities (D. Attig); (10) Energy efficiency in household, commerce, and industry - chances for market partnerships (H. Meixner); (11) Energy efficiency from the view of the heating industry (H. Schulte); (12) JI and CDM - Approaches for the marketing of energy efficient solutions (M.F. Zelinger).

Crystal structure and magnetic properties of PrCo6.8-xCuxHf0.2 compounds

International Nuclear Information System (INIS)

Luo, J; Liang, J K; Guo, Y Q; Liu, Q L; Liu, F S; Yang, L T; Zhang, Y; Rao, G H

2004-01-01

The effects of Cu substitution on the crystal structure and magnetic properties of PrCo 6.8-x Cu x Hf 0.2 (x = 0-1.0) compounds were investigated by means of x-ray powder diffraction and magnetic measurements. The as-cast PrCo 6.8-x Cu x Hf 0.2 compounds crystallize in the TbCu 7 -type structure with the space group P6/mmm. The Curie temperature and magnetic anisotropy field decrease with increasing Cu content. A spin reorientation behaviour has been observed in the PrCo 6.8-x Cu x Hf 0.2 compounds. The addition of Cu weakens the anisotropy of the Co sublattice, leading to an increase in the spin reorientation temperature with increasing content of Cu

alpha-decay spectroscopy of light odd-odd Bi isotopes - II sup 1 sup 8 sup 6 Bi and the new nuclide sup 1 sup 8 sup 4 Bi

CERN Document Server

Andreyev, A N; Ackermann, D; Münzenberg, G; Hessberger, F P; Hofmann, S; Kojouharov, I; Kindler, B; Lommel, B; Huyse, M; Vel, K V D; Duppen, P V; Heyde, Kris L G

2003-01-01

Alpha-decay of the new nuclide sup 1 sup 8 sup 4 Bi has been studied in the complete-fusion reaction sup 9 sup 3 Nb( sup 9 sup 4 Mo, 3n) sup 1 sup 8 sup 4 Bi at the velocity filter SHIP. The evaporation residues were separated in-flight and subsequently identified on the basis of recoil-alpha, recoil-alpha-gamma analysis and excitation functions measurements. Two alpha-decaying isomeric states in sup 1 sup 8 sup 4 Bi with half-life values of 13(2) ms and 6.6(1.5) ms were identified. The alpha-branching ratio of sup 1 sup 8 sup 0 Tl was deduced for the first time as b subalpha = (2-12)%. Improved data on the fine-structure alpha-decay of sup 1 sup 8 sup 6 Bi were obtained in the sup 9 sup 3 Nb( sup 9 sup 5 Mo, 2n) sup 1 sup 8 sup 6 Bi reaction. A similarity of the decay energies and half-life values of sup 1 sup 8 sup 4 sup , sup 1 sup 8 sup 6 Bi is pointed out and a possible explanation for this effect is suggested.

[Prescribing valproate to girls and women of childbearing age in Germany : Analysis of trends based on claims data].

Science.gov (United States)

Wentzell, Nadine; Haug, Ulrike; Schink, Tania; Engel, Susanne; Liebentraut, Judith; Linder, Roland; Onken, Marlies; Schaefer, Christof; Dathe, Katarina

2018-06-19

Measures to raise awareness of the teratogenic potential of valproate and restrict its use in girls/women of childbearing age have been intensified. For Germany, the impact of these measures on valproate prescription rates remains unknown. Trends in prescribing valproate, the underlying treatment indication, and the specialty of the prescribing physician are analyzed. With claims data from several statutory health insurance providers from 2004 to 2016 (approximately 3.5 million insured persons per year) considering treatment indication and medical specialties of prescribing physicians, we assessed the rate of girls/women (12 to 50 years) with at least one valproate dispensation per year. The age-standardized rate of girls/women with at least one valproate dispensation declined by 28% between 2004 and 2016 (2.91/1000 vs. 2.09/1000). For 2015, the indications were epilepsy (66.9%), bipolar disorder (13.6%), migraine/headache (5.6%), schizoaffective disorder (4.3%), and other mental disorders (8.9%). Among epilepsy patients, the proportion treated with valproate declined from 26.2 to 16.8%, but changed little in patients with bipolar disorder (9.3% vs. 8.0%). A total of 46.3% of valproate dispensations were issued by neurologists or psychiatrists and 29.6% by general practitioners, internal medicine specialists, or family doctors. Based on German claims data, a decline of valproate dispensations was shown for epilepsy patients of childbearing age, while the proportion in other indications has hardly changed since 2004.

Impact of improving vehicle front design on the burden of pedestrian injuries in Germany, the United States, and India.

Science.gov (United States)

Moran, Dane; Bose, Dipan; Bhalla, Kavi

2017-11-17

European car design regulations and New Car Assessment Program (NCAP) ratings have led to reductions in pedestrian injuries. The aim of this study was to evaluate the impact of improving vehicle front design on mortality and morbidity due to pedestrian injuries in a European country (Germany) and 2 countries (the United States and India) that do not have pedestrian-focused NCAP testing or design regulations. We used data from the International Road Traffic and Accident Database and the Global Burden of Disease project to estimate baseline pedestrian deaths and nonfatal injuries in each country in 2013. The effect of improved passenger car star ratings on probability of pedestrian injury was based on recent evaluations of pedestrian crash data from Germany. The effect of improved heavy motor vehicle (HMV) front end design on pedestrian injuries was based on estimates reported by simulation studies. We used burden of disease methods to estimate population health loss by combining the burden of morbidity and mortality in disability-adjusted life years (DALYs) lost. Extrapolating from evaluations in Germany suggests that improving front end design of cars can potentially reduce the burden of pedestrian injuries due to cars by up to 24% in the United States and 41% in India. In Germany, where cars comply with the United Nations regulation on pedestrian safety, additional improvements would have led to a 1% reduction. Similarly, improved HMV design would reduce DALYs lost by pedestrian victims hit by HMVs by 20% in each country. Overall, improved vehicle design would reduce DALYs lost to road traffic injuries (RTIs) by 0.8% in Germany, 4.1% in the United States, and 6.7% in India. Recent evaluations show a strong correlation between Euro NCAP pedestrian scores and real-life pedestrian injuries, suggesting that improved car front end design in Europe has led to substantial reductions in pedestrian injuries. Although the United States has fewer pedestrian crashes, it would

What's happening in 'renewable energy developed country: Germany'. Next step our country should learn

International Nuclear Information System (INIS)

Kitamura, Kazuya

2012-01-01

What's the next step our country should take? Japan could learn a lot of things such as success or failure examples from renewable energy developed country: Germany. This article reviewed present state of Feed-In Tariffs and renewable energy power in Germany. Share of renewable energy power amounted to 20% including 7.6% of wind power and 6.1% of biomass in 2011. Such trend caused increase of power cost, restructure of power system such as new installation of power transmission against north coast offshore wind power plant, and development of power storage system such as hydrogen production or pumped storage power plant. Efficient introduction of renewable energy should be planned in Japan based on appropriate share target of renewable energy share. As for nuclear power phaseout, Japan should learn German's experiences on decommissioning and decontamination of nuclear power plants, and policies of intermediate storage and final disposal of high-level radioactive wastes, which needed a long time and a great cost. (T. Tanaka)

The Role of Western Germany in West European Defense

Science.gov (United States)

1966-04-08

Ralph. Modern German History. New York: E. P. Dutton & Co., Inc., 1964. (DD175 F5) 34. German Research Association. Germany: Franz Steiner Verlag Gmb...and Rudolf , Walter. This Germany. New York: New York Graphic Society Publishers, Ltd., 1954. (DD257 L42) 39. Heidenheimer, Arnold J. The Government...202-07, 243. 47. Lauder, K. H. A Brief Review of Science and Technoloc in Western Germany. London: HIISO, 1955. (Q18 G4G7) 48. Leonhardt, Rudolf Walter

48 CFR 252.229-7002 - Customs exemptions (Germany).

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Customs exemptions... of Provisions And Clauses 252.229-7002 Customs exemptions (Germany). As prescribed in 229.402-70(b), use the following clause: Customs Exemptions (Germany) (JUN 1997) Imported products required for the...

Impact of ambient gases on the mechanism of [Cs8Nb6O19]-promoted nerve-agent decomposition.

Science.gov (United States)

Kaledin, Alexey L; Driscoll, Darren M; Troya, Diego; Collins-Wildman, Daniel L; Hill, Craig L; Morris, John R; Musaev, Djamaladdin G

2018-02-28

The impact of ambient gas molecules (X), NO 2 , CO 2 and SO 2 on the structure, stability and decontamination activity of Cs 8 Nb 6 O 19 polyoxometalate was studied computationally and experimentally. It was found that Cs 8 Nb 6 O 19 absorbs these molecules more strongly than it adsorbs water and Sarin (GB) and that these interactions hinder nerve agent decontamination. The impacts of diamagnetic CO 2 and SO 2 molecules on polyoxoniobate Cs 8 Nb 6 O 19 were fundamentally different from that of NO 2 radical. At ambient temperatures, weak coordination of the first NO 2 radical to Cs 8 Nb 6 O 19 conferred partial radical character on the polyoxoniobate and promoted stronger coordination of the second NO 2 adsorbent to form a stable diamagnetic Cs 8 Nb 6 O 19 /(NO 2 ) 2 species. Moreover, at low temperatures, NO 2 radicals formed stable dinitrogen tetraoxide (N 2 O 4 ) that weakly interacted with Cs 8 Nb 6 O 19 . It was found that both in the absence and presence of ambient gas molecules, GB decontamination by the Cs 8 Nb 6 O 19 species proceeds via general base hydrolysis involving: (a) the adsorption of water and the nerve agent on Cs 8 Nb 6 O 19 /(X), (b) concerted hydrolysis of a water molecule on a basic oxygen atom of the polyoxoniobate and nucleophilic addition of the nascent OH group to the phosphorus center of Sarin, and (c) rapid reorganization of the formed pentacoordinated-phosphorus intermediate, followed by dissociation of either HF or isopropanol and formation of POM-bound isopropyl methyl phosphonic acid (i-MPA) or methyl phosphonofluoridic acid (MPFA), respectively. The presence of the ambient gas molecules increases the energy of the intermediate stationary points relative to the asymptote of the reactants and slightly increases the hydrolysis barrier. These changes closely correlate with the Cs 8 Nb 6 O 19 -X complexation energy. The most energetically stable intermediates of the GB hydrolysis and decontamination reaction were found to be Cs 8 Nb 6 O

Conference on offshore wind energy development in France and Germany - Legal framework, research results and perspectives

International Nuclear Information System (INIS)

Schulz, Joerg; Schlegelmilch, Kai; Schulze, Karsten; Abromeit, Carolin; Jensen, Lars Bie; Svendsen, Anne; Schwebel, Olivier; Huebner, Gundula; Heidmann, Roger; Piet, Olivier; Roudil, Jean-Philippe; Fuchs, Tina

2010-01-01

The French-German office for Renewable energies (OFAEnR) organised a conference on offshore wind energy development in France and Germany. In the framework of this French-German exchange of experience, about 170 participants exchanged views on the actual policies, on the offshore potentialities of both countries and on the recent logistics, services, training and software innovations. This document brings together the available presentations (slides) made during this event: 1 - Opening talk by Joerg Schulz, Bremerhaven's Major; 2 - The Future of the Offshore Wind energy in Germany - Key elements of the German energy Concept (Kai Schlegelmilch); 3 - Offshore wind farms: A commercial perspective - Offshore projects profitability (Karsten Schulze); 4 - Offshore Wind Farms in the German EEZ - experiences with the German Approval Procedure: criteria for a successful approval procedure (Carolin Abromeit); 5 - Offshore Wind Parks and fishery in Denmark - Involvement and compensation of commercial fishery in Denmark (Lars Bie Jensen); 6 - Tourism, property value, residents interest and offshore parks - Usage conflicts or regional development? (Anne Svendsen); 7 - Logistics for offshore wind projects - classic ports usable? An overview (Roger Heidmann); 8 - Offshore wind energy and French harbours (Olivier Piet); 9 - French offshore wind power market and component suppliers (Jean-Philippe Roudil); 10 - Trident software - the Offshore Wind Manager. Review and Forecast after one year of construction (Tina Fuchs)

[14C]-radiolabeling of {[trans-(8β)]-6-methyl-1-(1-methylethyl) ergoline-8-carboxylic acid, 4-methoxycyclohexyl ester (Z)-2-buteneidioate (1:1)}

International Nuclear Information System (INIS)

Marzoni, G.; Wheeler, W.J.; Garbrecht, W.L.

1988-01-01

The 5HT 2 -receptor antagonist, [ 14 C]-labeled brace[trans-(8β)]-6-methyl-1-(1-methylethyl)ergoline-8-carboxylic acid, 4-methoxycyclohexyl ester (Z)-2-butenedioate (1:1)brace (LY281067) was synthesized from unlabeled 6-methyl-1-(1-methylethyl)ergoline-8-carboxylic acid. The [ 14 C] label was introduced into the carboxyl group attached to the 8 position of the ergoline nucleus. This site is stable to metabolism. The synthesis involves removal of an unlabeled carboxyl group and subsequent reinsertion of a [ 14 C]-labeled carboxyl group into the same position. The radiolabel is not introduced until near the end of the synthesis which allows for ease of handling and scale-up of intermediates. (author)

(2aR*,5S*,6aS*,8aS*,E-Ethyl 5-hydroxy-7,7,8a-trimethyl-8-oxo-2,2a,6,6a,7,8,8a,8b-octahydro-1H-pentaleno[1,6-bc]oxepine-4-carboxylate

Directory of Open Access Journals (Sweden)

Goverdhan Mehta

2012-12-01

Full Text Available The title compound, C17H24O5, featuring a 2-carbethoxy-3-oxepanone unit in its intramolecularly O—H...O hydrogen-bonded enol form, was obtained via [(CF3CO22Rh]2-catalysed intramolecular O—H bond insertion in the α-diazo-ω-hydroxy-β-ketoester, ethyl 4-[(1S,3aS,6R,6aS-6-hydroxy-2,2,3a-trimethyl-3-oxo-octahydropentalen-1-yl]-2-diazo-3-oxobutanoate. The seven-membered oxacyclic ring, thus constructed on a cis-fused diquinane platform, was found to adopt a distorted boat–sofa conformation.

Preparation and photocatalytic property of potassium niobate K6Nb10.8O30

International Nuclear Information System (INIS)

Zhang Gaoke; Zou Xi; Gong Jie; He Fangsheng; Zhang Hao; Zhang Qiang; Liu Ying; Yang Xia; Hu Bo

2006-01-01

The TB-type potassium niobate K 6 Nb 10.8 O 30 was synthesized by a simple solid-state reaction method. Scanning electron microscope (SEM) and X-ray diffractometer (XRD) were used to characterize the structure of the photocatalyst. The photocatalyst K 6 Nb 10.8 O 30 shows high photocatalytic activity to photodegrade acid red G under UV irradiation. The influences of catalyst dosage, initial concentration of acid red G on the photocatalytic reaction were investigated. The kinetics of photocatalytic degradation of acid red G follows the first order kinetics

Hysterectomy in Germany: a DRG-based nationwide analysis, 2005-2006.

Science.gov (United States)

Stang, Andreas; Merrill, Ray M; Kuss, Oliver

2011-07-01

Hysterectomy is among the more common surgical procedures in gynecology. The aim of this study was to calculate population-wide rates of hysterectomy across Germany and to obtain information on the different modalities of hysterectomy currently performed in German hospitals. This was done on the basis of nationwide DRG statistics (DRG = diagnosis-related groups) covering the years 2005-2006. We analyzed the nationwide DRG statistics for 2005 and 2006, in which we found 305 015 hysterectomies. Based on these data we calculated hysterectomy rates for the female population. We determined the indications for each hysterectomy with an algorithm based on the ICD-10 codes, and we categorized the operations on the basis of their OPS codes (OPS = Operationen- und Prozedurenschlüssel [Classification of Operations and Procedures]). The overall rate of hysterectomy in Germany was 362 per 100 000 person-years. 55% of hysterectomies for benign diseases of the female genital tract were performed transvaginally. Bilateral ovariectomy was performed concomitantly in 23% of all hysterectomies, while 4% of all hysterectomies were subtotal. Hysterectomy rates varied considerably across federal states: the rate for benign disease was lowest in Hamburg (213.8 per 100 000 women per year) and highest in Mecklenburg-West Pomerania (361.9 per 100 000 women per year). Hysterectomy rates vary markedly from one region to another. Moreover, even though recent studies have shown that bilateral ovariectomy is harmful to women under 50 who undergo hysterectomy for benign disease, it is still performed in 4% of all hysterectomies for benign indications in Germany.

Experimental study of spallation: neutron angular distributions induced by protons (0.8.,1.2 et 1.6 GeV) and deuterons (0.8 et 1.6 GeV) beams

International Nuclear Information System (INIS)

Borne, F.

1998-01-01

Angular distributions of spallation neutrons, produced by 0,8 to 1,6 GeV protons and 0,8 to 1,6 GeV deuterons, with two experimental and complementary techniques: the flight time measure and the use of a liquid hydrogen converter associated with a magnetic spectrometer of higher energy (2000 MeV). Experimental results obtained at Saturne (Cea) are analysed and interpreted. They allowed the determination of the neutrons production behaviour on thin targets (Al, Fe, Zr, W, Pb and Th) in function of the angle emission and the atomic number of the target and to compare the variation of neutrons production, coming from protons and incident deuterons of same total energy on a Pb target. Experimental results are compared with simulation results obtained with the TIERCE code, including Bertini and Cugnon intra-nuclear cascades. (A.L.B.)

Waste management concept during dismantling of KKS NPP in Germany

International Nuclear Information System (INIS)

Bacmeister, Georg U.

2008-01-01

Full text: This paper gives an overview on the waste management of NPP Stade during dismantling. The general idea is to reduce the radioactive waste to about three percentage of the complete dismantling mass. The NPP Stade in Germany was shut down in November 2003. After a transient phase the license for dismantling was given in 2005. In the following 8 years about 20.000 tones of steel and 120.000 tones of concrete will be put out by the dismantling. The yearly output of steel will by about 100 times higher than during the running time of the NNP. For this a new processes for waste management had to be installed. The waste management during dismantling focus on free release (about 97%). Beside some minor exception, the rest is deemed to be radioactive waste. This will be collected in 1000 packages, which are ready to be sent to a final storage. As until now in Germany no final storage is open (and sending of radioactive waste to another country is forbidden), the NNP Stade build an intermediate storage, where the packages may by saved for longest 40 years. The clearance procedure in Germany is regulated in the radiation protection ordinances. It is based on a nuclide specific set of clearance levels. To fulfil these demands the NNP Stade chose a semi automated system for characterization and documentation, which we develop in accordance to our release license. It guaranties a most accurate determination of the relevant nuclides for a set of dismantling material (some 10 to 100 tones). After the characterization only the gamma-activity of the material is measured in boxes of about 500 kg. A short comparison of the chosen procedure with other options, possible in Germany will be given and the decision from the collaboration with the NPP in Barsebaeck, Sweden, will be withdrawn. Beside the free release different options are used for waste management, like incineration, sending to landfill or reuse in nuclear industry. The waste management of the NNP Stade take

Characteristics of diabetic patients visiting a podiatry practice in Germany.

Science.gov (United States)

Lauterbach, S; Kostev, K; Becker, R

2010-04-01

To describe the foot characteristics of diabetic patients attending a podiatry practice for their first consultation. The objective was to determine how effectively diabetic foot ulcers are being prevented in primary care. All diabetic patients who presented at a podiatry practice between 2006 and 2008 for their first consultation were analysed. Anonymous data were obtained from the standard patient anamnesis sheet completed by the podiatrist. These included results of patient interviews and examinations. A total of 230 diabetic patients (93.9% had type 2 diabetes mellitus and 6.1% had type 1) were analysed. The mean age was 67.7 years (+/- 10.8). Just under half (47.4%) were female. The mean duration of diabetes was 12.6 years (+/- 10.5) years. 70.4% of the patients had diabetic neuropathy (confidence intervals: 64.5-76.3), of whom 73.2% already had resting foot pain or strain foot pain while walking. 58.3% of the patients had toenail mycosis, and of these 38.1% had the infection in all 10 toenails. Most of the patients had at least one foot deformities (89.6% splayfoot and 37.0% flatfoot). 40.2% had no sensation to microfilament testing on either their right or left foot toes. The overall mean vibration sensation test threshold was 3.7 (+/- 2.3). While there is a structure and strategy for the primary and secondary prevention of the diabetic foot ulcers, its delivery is often ineffective. This audit shows that, in Germany, the detection and prevention of diabetic foot problems in podiatric practices happens far too late.

Acceptance, Prevalence and Indications for Robot-Assisted Laparoscopy - Results of a Survey Among Urologists in Germany, Austria and Switzerland.

Science.gov (United States)

Imkamp, Florian; Herrmann, Thomas R W; Tolkach, Yuri; Dziuba, Sebastian; Stolzenburg, Jens U; Rassweiler, Jens; Sulser, Tullio; Zimmermann, Uwe; Merseburger, Axel S; Kuczyk, Markus A; Burchardt, Martin

2015-01-01

Robotic-assisted laparoscopy (RAL) is being widely accepted in the field of urology as a replacement for conventional laparoscopy (CL). Nevertheless, the process of its integration in clinical routines has been rather spontaneous. To determine the prevalence of robotic systems (RS) in urological clinics in Germany, Austria and Switzerland, the acceptance of RAL among urologists as a replacement for CL and its current use for 25 different urological indications. To elucidate the practice patterns of RAL, a survey at hospitals in Germany, Austria and Switzerland was conducted. All surgically active urology departments in Germany (303), Austria (37) and Switzerland (84) received a questionnaire with questions related to the one-year period prior to the survey. The response rate was 63%. Among the participants, 43% were universities, 45% were tertiary care centres, and 8% were secondary care hospitals. A total of 60 RS (Germany 35, Austria 8, Switzerland 17) were available, and the majority (68%) were operated under public ownership. The perception of RAL and the anticipated superiority of RAL significantly differed between robotic and non-robotic surgeons. For only two urologic indications were more than 50% of the procedures performed using RAL: pyeloplasty (58%) and transperitoneal radical prostatectomy (75%). On average, 35% of robotic surgeons and only 14% of non-robotic surgeons anticipated RAL superiority in some of the 25 indications. This survey provides a detailed insight into RAL implementation in Germany, Austria and Switzerland. RAL is currently limited to a few urological indications with a small number of high-volume robotic centres. These results might suggest that a saturation of clinics using RS has been achieved but that the existing robotic capacities are being utilized ineffectively. The possible reasons for this finding are discussed, and certain strategies to solve these problems are offered. © 2015 S. Karger AG, Basel.

8 x 8 fuel surveillance program at Monticello site - end of Cycle 6: fourth post-irradiation inspection, October 1978

International Nuclear Information System (INIS)

Skarshaug, N.H.

1980-09-01

A fuel surveillance program for a lead 8 x 8 reload fuel assembly was implemented at the Monticello Nuclear Power Station in May 1974 prior to Reactor Cycle 3. Inspection results of the fourth post-irradiation inspection performed on this surveillance fuel assembly in October 1978 at EOC 6, after a bundle average exposure of 25,900 MWd/MT, are presented. The measurement techniques, results obtained and comparisons to previous measurements are discussed. The bundle and individual rods examined exhibited characteristics of normal operation and were approved for continued irradiation during Monticello operating Cycle 7

The role of Germany in resolving the ukrainian crisis

Directory of Open Access Journals (Sweden)

Olena L. Hilchenko

2016-02-01

Full Text Available The article analyzes the participation of Germany in the matter of the Ukrainian crisis 2013-2015 and presents some approaches to the definition of the term «Ukrainian crisis». Reveals the reasons that lead Germany to take an active position in solving the Ukrainian question. Characterized the evolution of German-Russian relations from 90s to 2014, within which examined the St. Petersburg dialogue, «Pact of Putin-Schroeder», «Weimar triangle», «Partnership for modernization», Russian-Georgian conflict 2008. Available analysis of the new strategy of German foreign policy in 2012 «to support globalization – develop partnerships to share responsibility» and a new paradigm of German foreign policy presented in 2014 in the framework of the Munich conference on security policy. Examines the role of Germany in the European integration process of Ukraine during the Euromaidan events, the signing of the Association Agreement of Ukraine with the EU, ratification and future prospects of the enlargement of the European Union through the Eastern partnership countries. Presents the results of the public opinion of the population of Germany on this issue. Analyzes the position of the Germany government regarding the annexation of Crimea, the illegal referendum in Donetsk and Lugansk regions and the military aggression of Russian Federation against Ukraine. Presents description of the Germany role in the process of the diplomatic settlement of the military conflict in the East Ukraine in the framework of Norman four. On the example of polls are considered the public opinion of the population of Germany concerning possible ways of settlement the Ukrainian crisis. Presents the official position of the President of the Federal Republic of Germany. J. Gauck, Chancellor Merkel, Foreign Minister Frank-V. Steinmeier and Minister of Finance Schaeuble on certain issues of the Ukrainian crisis and the prolongations of sanctions against the Russian Federation

A Cross-Sectional Survey of Near-Infrared Spectroscopy Use in Pediatric Cardiac ICUs in the United Kingdom, Ireland, Italy, and Germany.

Science.gov (United States)

Hoskote, Aparna U; Tume, Lyvonne N; Trieschmann, Uwe; Menzel, Christoph; Cogo, Paola; Brown, Katherine L; Broadhead, Michael W

2016-01-01

Despite the increasing use of near-infrared spectroscopy across pediatric cardiac ICUs, there is significant variability and equipoise with no universally accepted management algorithms. We aimed to explore the use of near-infrared spectroscopy in pediatric cardiac ICUs in the United Kingdom, Ireland, Italy, and Germany. A cross-sectional multicenter, multinational electronic survey of one consultant in each pediatric cardiac ICU. Pediatric cardiac ICUs in the United Kingdom and Ireland (n = 13), Italy (n = 12), and Germany (n = 33). Questionnaire targeted to establish use, targets, protocols/thresholds for intervention, and perceived usefulness of near-infrared spectroscopy monitoring. Overall, 42 of 58 pediatric cardiac ICUs (72%) responded: United Kingdom and Ireland, 11 of 13 (84.6%); Italy, 12 of 12 (100%); and Germany, 19 of 33 (57%, included all major centers). Near-infrared spectroscopy usage varied with 35% (15/42) reporting that near-infrared spectroscopy was not used at all (7/42) or occasionally (8/42); near-infrared spectroscopy use was much less common in the United Kingdom (46%) when compared with 78% in Germany and all (100%) in Italy. Only four units had a near-infrared spectroscopy protocol, and 18 specifically used near-infrared spectroscopy in high-risk patients; 37 respondents believed that near-infrared spectroscopy added value to standard monitoring and 23 believed that it gave an earlier indication of deterioration, but only 19 would respond based on near-infrared spectroscopy data alone. Targets for absolute values and critical thresholds for intervention varied widely between units. The reasons cited for not or occasionally using near-infrared spectroscopy were expense (n = 6), limited evidence and uncertainty on how it guides management (n = 4), difficulty in interpretation, and unreliability of data (n = 3). Amongst the regular or occasional near-infrared spectroscopy users (n = 35), 28 (66%) agreed that a multicenter study is warranted

2-tert-Butyl-5,6,7,8,9,10-hexahydrocyclohepta[b]indole

Directory of Open Access Journals (Sweden)

Janina Wobbe

2011-09-01

Full Text Available 2-tert-Butyl-5,6,7,8,9,10-hexahydrocyclohepta[b]indole was synthesized by reaction of cycloheptanone and (4-tert-butylphenylhydrazine hydrochloride in the presence of sodium acetate and sulfuric acid in glacial acetic acid via Fischer indole synthesis.

The exposition of John 17:6-8: An exegetical exercise

Directory of Open Access Journals (Sweden)

D.G. van der Merwe

2003-10-01

Full Text Available This essay is an exegesis of Jn 17:6-8 aimed at gaining an understanding of what the Fourth Evangelist tries to emphasize and to communicate concerning the character and success of Jesus This essay is an exegesis of Jn 17:6-8 aimed at gaining an understanding of what the Fourth Evangelist tries to emphasize and to communicate concerning the character and success of Jesus’ earthly ministry. Firstly, a discourse analysis is conducted to point out the linguistic symmetric parallelism through which the Evangelist (1 emphasizes the success of Jesus’ ministry, (2 structures the principal components of Jesus’ ministry and the response of his disciples and (3 tries to explain the meaning of these components. Secondly, a theological exposition of these principal components is conducted, in respect of (1 Revelation: … (2 Obedience /Acceptance: … and (3 Faith: … ( earthly ministry. Firstly, a discourse analysis is conducted to point out the linguistic symmetric parallelism through which the Evangelist (1 emphasizes the success of Jesus’ ministry, (2 structures the principal components of Jesus’ ministry and the response of his disciples and (3 tries to explain the meaning of these components. Secondly, a theological exposition of these principal components is conducted, in respect of (1 Revelation: … (2 Obedience / Acceptance: … and (3 Faith: … (

The UGT1A6_19_GG genotype is a breast cancer risk factor

Directory of Open Access Journals (Sweden)

Christina eJustenhoven

2013-06-01

Full Text Available Validation of an association between the UGT1A6_19_T>G (rs6759892 polymorphism and overall breast cancer risk. A pilot study included two population-based case-control studies from Germany (MARIE-GENICA. An independent validation study comprised four independent breast cancer case-control studies from Finland (KBCP, OBCS, Germany (BBCC and Sweden (SASBAC. The pooled analysis included 7,418 cases and 8,720 controls from all six studies. Participants were of European descent. Genotyping was done by MALDI-TOF MS and statistical analysis was performed by logistic regression adjusted for age and study. The increased overall breast cancer risk for women with the UGT1A6_19_GG genotype which was observed in the pilot study was confirmed in the set of four independent study collections (OR 1.13, 95% CI 1.05-1.22; p = 0.001. The pooled study showed a similar effect (OR 1.09, 95% CI 1.04-1.14; p = 0.001. We confirmed the association of UGT1A6_19_GG with increased overall breast cancer risk and conclude that our result from a well powered multi-stage study adds a novel candidate to the panel of validated breast cancer susceptibility loci.

Public perceptions of cohort studies and biobanks in Germany.

Science.gov (United States)

Starkbaum, Johannes; Gottweis, Herbert; Gottweis, Ursula; Kleiser, Christina; Linseisen, Jakob; Meisinger, Christa; Kamtsiuris, Panagiotis; Moebus, Susanne; Jöckel, Karl-Heinz; Börm, Sonja; Wichmann, H-Erich

2014-04-01

Cohort studies and biobank projects have led to public discussions in several European countries in the past. In Germany, many medium-sized studies are currently running successfully in terms of respondent rates. However, EU-wide research on general public perceptions of biobanks and cohort studies have shown that Germany is among those countries where people express the highest reluctance for providing body material and other data for research purposes. Because of early efforts of the just-initiated German National Cohort Study, we are able to begin to investigate in greater detail how various groups of people across Germany reflect and discuss the ongoing implementation of cohort studies and biobanking in Germany. Our research is based on 15 focus group discussions in four German regions, as well as on Eurobarometer poll data on biobanking.

Anaplasma phagocytophilum and Babesia spp. in roe deer (Capreolus capreolus), fallow deer (Dama dama) and mouflon (Ovis musimon) in Germany.

Science.gov (United States)

Kauffmann, Melanie; Rehbein, Steffen; Hamel, Dietmar; Lutz, Walburga; Heddergott, Mike; Pfister, Kurt; Silaghi, Cornelia

2017-02-01

Infections with the tick-borne pathogens Anaplasma phagocytophilum and Babesia spp. can cause febrile disease in several mammalian species, including humans. Wild ruminants in Europe are suggested to serve as reservoir hosts for particular strains or species of these pathogens. The aims of this study were to investigate the occurrence of A. phagocytophilum and Babesia spp. in roe deer (Capreolus capreolus), fallow deer (Dama dama) and mouflon (Ovis musimon orientalis) in Germany, and the diversity and host association of genetic variants of A. phagocytophilum and Babesia species. From 2009 to 2010, 364 spleen samples from 153 roe deer, 43 fallow deer and 168 mouflon from 13 locations in Germany were tested for DNA of A. phagocytophilum and Babesia spp. by real-time PCR or conventional PCR, respectively. Variants of A. phagocytophilum were investigated with a nested PCR targeting the partial 16S rRNA gene, and species of piroplasms were identified by sequencing. DNA of A. phagocytophilum was detected in 303 (83.2%) samples: roe deer, 96.1% (147/153); fallow deer, 72.1% (31/43); and mouflon, 74.4% (125/168). Sequence analysis of 16S rRNA-PCR products revealed the presence of nine different genetic variants. DNA of Babesia spp. was found in 113 (31.0%) samples: roe deer, 62.8% (96/153); fallow deer, 16.3% (6/43); and mouflon, 6.5% (11/168). Babesia capreoli, Babesia sp. EU1 (referred to also as B. venatorum), B. odocoilei-like and a Theileria species were identified. Co-infections with A. phagocytophilum and Babesia spp. were detected in 30.0% of the animals which were tested positive for A. phagocytophilum and/or Babesia spp. Roe deer had a significantly higher percentage of co-infections (60.8%), followed by fallow deer (14.0%) and mouflon (6.5%). Thus, the results suggest that roe deer plays a key role in the endemic cycles of the pathogens investigated. Copyright © 2016 Elsevier Ltd. All rights reserved.

(1R,4R,6S,7R-5,5-Dibromo-1,4,8,8-tetramethyltricyclo[5.4.1.04,6]dodecan-12-one

Directory of Open Access Journals (Sweden)

Mohamed Zaki

2014-05-01

Full Text Available The title compound, C16H24Br2O, was synthesized from the reaction of β-himachalene (3,5,5,9-tetramethyl-2,4a,5,6,7,8-hexahydro-1H-benzocycloheptene, which was isolated from Atlas cedar (Cedrus atlantica. The asymmetric unit contains two independent molecules with similar conformations. Each molecule is built up from two fused seven-membered rings and an additional three-membered ring. In both molecules, one of the seven-membered rings has a chair conformation, whereas the other displays a screw-boat conformation.

Greenhouse gas neutral Germany in 2050

International Nuclear Information System (INIS)

Benndorf, Rosemarie; Bernicke, Maja; Bertram, Andreas

2014-01-01

In order to answer the question how a greenhouse gas neutral Germany would look like an interdisciplinary process was started by the Federal Environmental Agency. It was clear from the beginning of this work that a sustainable regenerative energy supply could not be sufficient. Therefore all relevant emission sources were included into the studies: traffic, industry, waste and waste water, agriculture, land usage, land usage changes and forestry. The necessary transformation paths to reach the aim of a greenhouse gas neutral Germany in 2050, economic considerations and political instruments were not part of this study.

Chevrel-phase solid solution Mo 6Se 8- xTe x. Study of its superconducting, magnetic and NMR properties

Science.gov (United States)

Hamard1a, C.; Auffret, V.; Peña, O.; Le Floch, M.; Nowak, B.; Wojakowski, A.

2000-09-01

The Chevrel-phase solid solution Mo 6Se 8-Mo 6Te 8 was studied by X-ray diffraction, AC and DC magnetic susceptibility and 77Se and 125Te NMR spectroscopy. From the smooth evolution of the lattice parameters and superconducting critical temperatures, a progressive substitution of selenium atoms by tellurium is shown, on the whole range of composition 0⩽ x⩽8, in the formulation Mo 6Se 8- xTe x: the unit-cell volume increases linearly because of the larger ionic size of tellurium, while Tc decreases rapidly (from 6.45 down to 0 K) because of the different formal oxidation states of the anions and a probable evolution of the Fermi level in the density of states. Results of magnetic susceptibility support this model and suggest the inhibition of the intrinsic metallic behavior with increasing x. The NMR spectra of the binaries Mo 6Se 8 and Mo 6Te 8 reveal two significant features, attributed to two different chalcogen positions in the R 3¯ symmetry. At low Se contents in Mo 6Se 8- xTe x ( x=7.5, 7 and 6), selenium first fills the two X(2) sites along the three-fold axis (2c positions), and then it becomes statistically distributed over the general 6f positions, leading to broad 77Se NMR lines. On the other hand, substitution of Te atoms in Mo 6Se 8 seems to occur in a random way, creating large perturbations on the 125Te NMR spectra, over the whole range of x. Theoretical analysis based on the presence of two anisotropic lines (of axial and non-axial symmetries, respectively) allowed us to estimate their anisotropy factors and to perfectly simulate the frequency response of both Mo 6Se 8 and Mo 6Te 8 binaries. Analysis of the Knight shift anisotropy leads us to conclude about the importance of the molybdenum z 2 molecular orbital contribution which controls the Mo-X dipolar interactions.

Nuclear power perspectives for Germany

International Nuclear Information System (INIS)

Anon.

1992-01-01

Approximately 300 experts from the power industries, of research and politics, from Germany and abroad followed the invitation of the Deutsches Atomforum (DAtF) to meet at the traditional winter meeting held in Bonn on January 28 and 29, 1992, in order to discuss topical political issues, not only relating to nuclear power, but to primary energy supply in general. Bonn having been chosen as the place for the 1992 meeting, there were unusually many members of Parliament and members of the Federal German Government attending the conference. The four sessions of the conference were devoted to the following aspects: Perspectives, the world energy market, current issues of energy policy in Germany, and preventive risk management. (orig.) [de

[Dog tourism and import: an inquiry in Germany on the extent as well as on the spectrum and preference of countries of residence and origin respectively].

Science.gov (United States)

Glaser, B; Gothe, R

1998-05-01

A survey was conducted among practicing veterinarians and at pet clinics in Germany in order to estimate the extent of tourism with dogs and import of dogs and to determine the range and preference of the foreign countries involved. The survey covered the years from 1985 to 1995 and included 5240 dogs, of which 4567 (87.2%) were born in Germany and 673 (12.8%) were born abroad. Among the latter, 263 (39.1%) originated from Mediterranean countries and Portugal, 344 (51.1%) were born in other European countries and 66 (9.8%) were from non-European countries. Of all 5240 dogs surveyed, 2894 (55.2%) had been taken abroad at least once between 1985 and 1995. Of these, 2424 (53.1%) were born in Germany, 470 (69.8%) were born abroad. Of the 2894 dogs taken abroad, 1929 (66.7%) travelled to Mediterranean countries or Portugal and 1152 of these had additional travels to other countries as well. The spectrum of all countries travelled to was very broad, but numerous dogs were taken regularly, repeatedly and exclusively to Austria, Switzerland, Italy, Spain or France. Other countries were visited only once for the majority of dogs. The analysis of the annual survey data revealed a steady increase of dogs along on trips from Germany to other countries, rising from 31.1% in 1990 to 40.8% in 1994. In any of these years, always more than 56% of these dogs were taken to Mediterranean countries.

Measles, mumps, rubella, and varicella seroprevalence in refugees in Germany in 2015.

Science.gov (United States)

Jablonka, Alexandra; Happle, Christine; Grote, Ulrike; Schleenvoigt, Benjamin Thomas; Hampel, Annika; Dopfer, Christian; Hansen, Gesine; Schmidt, Reinhold Ernst; Behrens, Georg M N

2016-12-01

The current extent of migration poses emerging socio-economic and humanitarian challenges. Little is known on vaccination rates in migrants entering Europe, and the implementation of guidelines for serological testing and vaccination of refugees are pending. We conducted seroprevalence analyses for measles, mumps, rubella and varicella (MMRV) in 678 refugees coming to Germany during the current crisis. The mean age of refugees was 28.8±11.4 years, and 76.1 % of subjects were male. Overall, IgG seronegativity was 7.4 % (95 % CI 5.5-9.6) for measles, 10.2 % (95 % CI 8.0-12.5) for mumps, 2.2 % (95 % CI 1.2-3.4) for rubella, and 3.3 % (95 % CI 1.9-4.9) for varicella. Seropositivity rates were age-dependent with considerably low values in children. For example, overall MMR immunity was 90.9 % (95 % CI 88.8-93.1), but only 73.1 % of minor aged refugees displayed complete seroprevalence against all three diseases, and only 68.9 % of children and adolescents were completely MMRV immune. Our initial data set suggests overall satisfactory MMRV immunity in adult migrants coming to Europe, but the observed low MMRV seroprevalences in refugee children support thorough and prompt vaccination of young migrants entering Europe. Taken together, our data set underlines the urgent need to implement and validate vaccination guidelines for refugee care in the current crisis.

The Compatibility of Developed Mathematics Textbooks' Content in Saudi Arabia (Grades 6-8) with NCTM Standards

Science.gov (United States)

Alshehri, Mohammed Ali; Ali, Hassan Shawki

2016-01-01

This study aimed to investigate the compatibility of developed mathematics textbooks' content (grades 6-8) in Saudi Arabia with NCTM standards in the areas of: number and operations, algebra, geometry, measurement, data analysis and probability. To achieve that goal, a list of (NCTM) standards for grades (6-8) were translated to Arabic language,…

Year 2 of Germany's Energy Transition

International Nuclear Information System (INIS)

Cruciani, Michel

2013-01-01

After a decade characterised by the take-off of renewable energies, Germany decided in 2010 to make them the top priority. At the same time, it decided to make exemplary efforts in terms of energy efficiency and the reduction of greenhouse gases. The audacious nature of this policy was strengthened by the 'turn' taken in 2011 to give up nuclear energy in the wake of the Fukushima accident. Given the initial results for 2012, Germany seems to be on target for reaching its national objective, of 18% renewable energy within total consumption by 2020. Germany is also well placed to reduce its planned cut in electricity consumption of 10%. The country will also meet its commitments, both international and European, concerning greenhouse gas emissions. In contrast, recent trends suggest it will be increasingly difficult for Germany to meet its own, domestic goal of cutting emissions by 40%, by 2020. Furthermore, it is hard to see how Germany will be able to bring down total energy consumption by 20% by 2020 (from 2008 levels), or increase the share of renewables in electricity production above 35%. Success with this latter objective is largely dependent on reinforcing networks, both for transmission over long distances and for local distribution. It is not sure that the delays accumulated in both areas will be made up for by 2020, despite the rapid legislative adjustments that have already been made. By favouring intermittent energy sources - wind and solar power - Germany also faces problems of managing frequent production fluctuations. The long term solution to this lies in storing electricity. However, despite the considerable efforts in research and development, the technologies necessary for this will doubtless not be available on a large scale before the end of the present decade. These efforts could nevertheless provide German industry with interesting advantages in sectors of high potential, such as electric vehicles. Measures to promote renewable energies are

Conference on the role of biomethane in the energy transition in France and in Germany

International Nuclear Information System (INIS)

Reizine, Stanislas; Edel, Matthias; Theobald, Olivier; Pierre, Frederic; Mestrel, Jean Marc; Grope, Johan; Scholwin, Frank; Eberlein, Jens; Renard, Suzanne; Trommler, Marcus; Demeusy, Tatiana; Chapelat, Nicolas; Lefebvre, Mathieu

2015-01-01

The French-German office for Renewable energies (OFAEnR) organised a conference on the role of biomethane in the energy transition in France and in Germany. In the framework of this French-German exchange of experience, about 110 participants exchanged views on the status of the legal framework and of the development of biomethane industry in the French and German energy transitions. This document brings together the available presentations (slides) made during this event: 1 - Biomethane injection in France - elaboration and implementation of the price structure (Stanislas Reizine); 2 - Biomethane framework conditions in Germany 3 - German Road-map for Biomethane (Matthias Edel); 4 - A vision for biomethane in France in 2030 - purified biogas injection in the natural gas network (Olivier Theobald); 5 - Biomethane produced by the Strasbourg-la Wantzenau waste water plant and injected into the GDS natural gas network (Frederic Pierre); 6 - Biomethane fuel in Lille city: 1995-2015 100% clean and renewable energy in transportation (Jean Marc Mestrel); 7 - Biomethane from organic waste and its utilisation (Johan Grope); 8 - Marketing of Biomethane to end consumers (Jens Eberlein); 9 - Developing new approaches to promote injection into the grid (Suzanne Renard); 10 - Demand driven power supply from Bioenergy - a balancing option for power distribution networks (Marcus Trommler); 11 - Flexible biogas production and its integration to power and gas grids (Tatiana Demeusy); 12 - A partnership for the development of Agricultural methanization plants around a single injection point (Nicolas Chapelat); 13 - Keynotes: biomethane development paths to favour (Mathieu Lefebvre)

[Performance of in vitro fertilization in Germany].

Science.gov (United States)

van der Ven, Hans; Montag, Markus; van der Ven, Katrin

2002-07-01

In Germany the application of assisted reproductive techniques (ART) is regulated by federal legislation. Compared with the international situation the "German Embryo Protection Law" is very "restrictive" and various methods of ART are prohibited, e.g. oocyte/embryo donation, embryo cryopreservation and Preimplantation Genetic Diagnosis (PGD). Furthermore, in Germany only 1 to 3 fertilized oocytes may be cultured to embryo. All these embryos then have to be transferred into the uterus of a particular patient. Additional fertilized oocytes can only be cryopreserved in a pronuclear state. The success rate of ART has increased significantly over the past few years owing to the introduction of blastocyst cultures and the selection of 1 to 2 good quality blastocysts for embryo transfer. Furthermore, the transfer of only 1 to 2 blastocysts effectively reduces the risk of high rank multiple pregnancies. In Germany, however, the selection of only a few good quality blastocysts for transfer is prohibited by law. New laboratory techniques, e.g. pronuclear scoring and polar body biopsy screening for aneuploidy are in accordance with German law. The application of these methods provides a selection of "good quality oocytes" and seems to increase the overall success rate. Further studies are required, however. The success rate, quality and cost effectiveness of ART in Germany appears compromised when compared with many other countries. What is more, in contrast to the international situation research and development in ART in Germany has been decreasing constantly over the past few years, due to the inappropriate regulations of the German health care system and the insufficient support given to university-based centers.

Polarization and pressure effects in caesium 6S-8S two-photon spectroscopy

International Nuclear Information System (INIS)

Lee, Yi-Chi; Tsai, Chin-Chun; Chui, Hsiang-Chen; Chang, Yi-Hsiu; Chen, Ying-Yu

2010-01-01

This work analyses the effects of polarization and pressure in caesium 6S-8S two-photon spectroscopy. The linewidth was broadened and the frequency was shifted by a change of polarization states. The frequency shift and the linewidth broadening of the caesium 6S-8S two-photon transition were measured as a function of laser power using one single-frequency Ti:sapphire ring cavity laser, two caesium cells and two quarter-wave plates to ensure polarization states of light, and we showed that the linewidth cannot be evaluated just by fitting data to a Lorentzian shape. As determined by fitting the data to a Voigt profile, the natural linewidth is independent of the polarization states of the pump beams, the laser power and the pressure. Caesium 6S-8S two-photon transitions pumped by a circularly polarized beam have narrower linewidths and smaller shifts than those pumped by a linearly polarized beam. The light shift obtained by pumping with the circularly polarized beam is -6.75(57) Hz (mW mm -2 ) -1 , and that obtained by pumping with a linearly polarized beam is -7.25(45) Hz (mW mm -2 ) -1 . These results agree closely with theoretical calculations. The pressure shift is -588(387) Hz mPa -1 . This work shows how to evaluate two-photon transitions with a Voigt profile, and then helps us to understand two-photon transitions with different polarization states, and improve the signal quality obtained when they are used as frequency markers.

The prevalence of amblyopia in Germany: data from the prospective, population-based Gutenberg Health Study.

Science.gov (United States)

Elflein, Heike M; Fresenius, Susanne; Lamparter, Julia; Pitz, Susanne; Pfeiffer, Norbert; Binder, Harald; Wild, Philipp; Mirshahi, Alireza

2015-05-08

Amblyopia is due to insufficient development of the visual system in early childhood and is a major source of lifelong impairment of visual acuity. Too little is known about the prevalence of amblyopia in Germany and the frequency of its various causes. The Gutenberg Health Study of the University of Mainz Faculty of Medicine is an ongoing population-based, prospective, monocentric cohort study with 15 010 participants aged 35 to 74. All participants are examined for the presence of ocular, cardiovascular, neoplastic, metabolic, immunologic, and mental diseases. 3227 participants aged 35 to 44 underwent ophthalmological examination from 2007 to 2012. Amblyopia was defined as impaired visual acuity in the absence of any organic pathology capable of explaining the condition, and in the presence of a known risk factor for amblyopia. Amblyopia, when defined as a visual acuity less than or equal to 0.63, was present in 182 participants (5.6%, 95% confidence interval [CI] 4.9-6.5%), 120 of whom had a visual acuity less than or equal to 0.5 (3.7%, 95% CI 3.3-5.2%). A narrower definition of amblyopia requiring, in addition, an interocular difference in acuity of at least two lines yielded slightly lower prevalence figures: 5.0% (95% CI 4.2-5.8%) and 3.7% (95% CI 3.1-4.4%), respectively. The causes of amblyopia (visual acuity ≤ 0.63) were anisometropia (different refractive strengths of the two eyes) in 49% of participants, strabismus (a squint) in 23%, both of these factors in 17%, and visual deprivation in 2%. 3 patients (2%) had relative amblyopia due to a traumatic cataract sustained in early childhood. 7% of the participants with amblyopia had binocular amblyopia. This study yielded a prevalence figure of 5.6% for amblyopia in Germany-a higher figure than in other, comparable population-based studies, which have generally yielded figures of ca. 3% for visual acuity ≤ 0.63. The distribution of the causes of amblyopia is similar across studies.

The energy policy turnaround in Germany. With safe, costs affordable and environmentally-friendly energy by the year 2050. Special edition; Die Energiewende in Deutschland. Mit sicherer, bezahlbarer und umweltschonender Energie ins Jahr 2050. Sonderheft

Energy Technology Data Exchange (ETDEWEB)

NONE

2012-02-15

Within the contribution under consideration, the Federal Ministry of Economics and Technology (Berlin, Federal Republic of Germany) reports on the energy policy turnaround in Germany under special consideration of safe, costs affordable and environmentally-friendly energy by the year 2050. This contribution consists of the following chapters: (1) The Federal Government starts a new chapter in the energy policy; (2) The transformation of the energy markets should be cost-efficient as possible; (3) The grid extension is the fundament for a further extension of renewable energies; (4) New gas and coal power plants also are necessary in the future for maintaining the security of supply; (5) The renewable energy moved a step closer to the market; (6) Capital investments in new energy technologies are worthwhile; (7) Increased energy efficiency is a central requirement for the transformation of the energy supply; (8) We need Europe as a partner for the transformation of the energy supply in Germany; (9) A good foreign energy policy is a guarantor for a safe energy supply.

Deep Geothermal Energy Production in Germany

Directory of Open Access Journals (Sweden)

Thorsten Agemar

2014-07-01

Full Text Available Germany uses its low enthalpy hydrothermal resources predominantly for balneological applications, space and district heating, but also for power production. The German Federal government supports the development of geothermal energy in terms of project funding, market incentives and credit offers, as well as a feed-in tariff for geothermal electricity. Although new projects for district heating take on average six years, geothermal energy utilisation is growing rapidly, especially in southern Germany. From 2003 to 2013, the annual production of geothermal district heating stations increased from 60 GWh to 530 GWh. In the same time, the annual power production increased from 0 GWh to 36 GWh. Currently, almost 200 geothermal facilities are in operation or under construction in Germany. A feasibility study including detailed geological site assessment is still essential when planning a new geothermal facility. As part of this assessment, a lot of geological data, hydraulic data, and subsurface temperatures can be retrieved from the geothermal information system GeotIS, which can be accessed online [1].

An Investigation of Attitudes of 6-8th Graders Towards Universal Values

Directory of Open Access Journals (Sweden)

Ender DURUALP

2012-10-01

Full Text Available This study aims to describe attitudes of 6-8th graders towards universal values and examine the impact of their age, gender, grade level, academic performance, parental level of education, and family income on their attitudes towards universal values. The population consisted of 6-8th graders being taught in primary schools in Çankırı, Turkey. The sample consisted of 361 students (203 girls, 158 boys randomly selected from Çankırı İsmet İnönü Elementary School located in Çankırı which attracts the highest number of students from each level of socioeconomic status. The sociodemographic data of children and their parents were collected through a “General Information Form”, and the data related to attitudes towards universal values were obtained by the “Attitude Towards Universal Values Scale” developed by Demir and Koç (2009. Data were analyzed through Kolmogorov-Smirnov, Mann-Whitney U, Kruskal-Wallis H tests, and Cronbach Alpha (α reliability coefficient. Results showed that girls (p>0.05, 8th graders, academically-talented children, those whose parents are university graduates, and those with a family income of minimum wage or more have more positive attitudes towards universal values (p<0.05.

Managing ageing workforces: Empirical evidence from Germany

OpenAIRE

Drew, H.

2013-01-01

Demographic change (ageing populations and falling birth rates) affects all industrialised nations, including Germany. Traditionally, the problems associated with managing numbers of older workers were mitigated by the Altersteilzeitgesetz in Germany. Under this law, firms were offered financial support by the government to offer early retirement (Müller-Camen et al. 2009). As these provisions came to an end in 2010, the need to find alternative solutions to displacing older workers, as well ...

Inequality-adjusted gender wage differentials in Germany

OpenAIRE

Selezneva, Ekaterina; Van Kerm, Philippe

2013-01-01

This paper exploits data from the German Socio-Economic Panel (SOEP) to re-examine the gender wage gap in Germany on the basis of inequality-adjusted measures of wage differentials which fully account for gender differences in pay distributions. The inequality-adjusted gender pay gap measures are significantly larger than suggested by standard indicators, especially in East Germany. Women appear penalized twice, with both lower mean wages and greater wage inequality. A hypothetical risky inve...

Persistent Educational Advantage Across Three Generations: Empirical Evidence for Germany

Directory of Open Access Journals (Sweden)

Andrea Ziefle

2016-12-01

Full Text Available This article uses survey data from the German Socio-Economic Panel (GSOEP to analyze the persistence of educational attainment across three generations in Germany. I obtain evidence of a robust effect of grandparents' education on respondents' own educational attainment in West Germany, net of parental class, education, occupational status, family income, parents' relationship history, and family size. I also test whether the grandparent effect results from resource compensation or cumulative advantage and find empirical support for both mechanisms. In comparison, the intergenerational association between grandparents' and respondents' education is considerably weaker in East Germany and is also mediated completely by parental education. There are hardly any gender differences in the role of grandparents for respondents’ educational attainment, except for the fact that resource compensation is found to be exclusively relevant for women’s attainment in both West Germany and in East Germany after German reunification and the associated transition to an open educational system.

Insurability and mitigation of flood losses in private households in Germany.

Science.gov (United States)

Thieken, Annegret H; Petrow, Theresia; Kreibich, Heidi; Merz, Bruno

2006-04-01

In Germany, flood insurance is provided by private insurers as a supplement to building or contents insurance. This article presents the results of a survey of insurance companies with regard to eligibility conditions for flood insurance changes after August 2002, when a severe flood caused 1.8 billion euro of insured losses in the Elbe and the Danube catchment areas, and the general role of insurance in flood risk management in Germany. Besides insurance coverage, governmental funding and public donations played an important role in loss compensation after the August 2002 flood. Therefore, this article also analyzes flood loss compensation, risk awareness, and mitigation in insured and uninsured private households. Insured households received loss compensation earlier. They also showed slightly better risk awareness and mitigation strategies. Appropriate incentives should be combined with flood insurance in order to strengthen future private flood loss mitigation. However, there is some evidence that the surveyed insurance companies do little to encourage precautionary measures. To overcome this problem, flood hazards and mitigation strategies should be better communicated to both insurance companies and property owners.

Research center Juelich to install Germany's most powerful supercomputer new IBM System for science and research will achieve 5.8 trillion computations per second

CERN Multimedia

2002-01-01

"The Research Center Juelich, Germany, and IBM today announced that they have signed a contract for the delivery and installation of a new IBM supercomputer at the Central Institute for Applied Mathematics" (1/2 page).

Two-proton pickup studies with the (6Li,8B) reaction

International Nuclear Information System (INIS)

Weisenmiller, R.B.

1976-01-01

The ( 6 Li, 8 B) reaction has been investigated on targets of 26 Mg, 24 Mg, 16 O, 13 C, 12 C, 11 B, 10 B, and 9 Be at a bombarding energy of 80.0 MeV, and on targets of 16 O, 12 C, 9 Be, 7 Li, and 6 Li at a bombarding energy of 93.3 MeV. Only levels consistent with direct, single-step two-proton pickup reaction mechanisms were observed to be strongly populated. On T/sub z/ = 0 targets, the spectroscopic selectivity of this reaction resembles that of the analogous (p,t) reaction. Additionally, these data demonstrate the dominance of spatially symmetric transfer of the two protons. On T/sub z/ greater than 0 targets the ( 6 Li, 8 B) reaction was employed to locate two previously unreported levels (at 7.47 +- 0.05 MeV and 8.86 +- 0.07 MeV) in the T/sub z/ = 2 nuclide 24 Ne and to establish the low-lying 1p-shell states in the T/sub z/ = 3 / 2 nuclei 11 Be, 9 Li, and 7 He. However, no evidence was seen for any narrow levels in the T/sub z/ = 3 / 2 nuclide 5 H nor for any narrow excited states in 7 He. The angular distributions reported here are rather featureless and decrease monotonically with increasing angle. This behavior can be shown by a semi-classical reaction theory to be a consequence of the reaction kinematics. A semi-classical approach also suggests that the kinematic term in the transition matrix element is only weakly dependent upon the angular momentum transfer (which is consistent with simple Distorted Wave Born Approximation calculations). However, only qualitative agreement was obtained between the observed relative transition yields and semi-classical predictions, using the two-nucleon coefficients of fractional parentage of Cohen and Kurath, probably due to the limitations of the semi-classical reaction theory

Comparative treatment patterns, healthcare resource utilization and costs of atomoxetine and long-acting methylphenidate among children and adolescents with attention-deficit/hyperactivity disorder in Germany.

Science.gov (United States)

Greven, Peter; Sikirica, Vanja; Chen, Yaozhu J; Curtice, Tammy G; Makin, Charles

2017-09-01

Attention-deficit/hyperactivity disorder (ADHD) imposes a substantial burden on patients and their families. A retrospective, propensity score-matched cohort study compared treatment patterns, healthcare resource utilization (HRU) and costs among children/adolescents with ADHD aged 6-17 years at treatment initiation (index) in Germany who received atomoxetine (ATX) or long-acting methylphenidate (LA-MPH) monotherapy. Patients received at least one prescription for their index medication (ATX/LA-MPH) during 2006-2010; the first prescription marked the index date. ATX- and LA-MPH-indexed cohorts were matched 1:1 (n = 737); a patient subset was identified that had not received ADHD-indicated medications in 12 months prior to index (novel initiators: ATX, n = 486; LA-MPH, n = 488). Treatment patterns were evaluated among novel initiators, and HRU and costs among the matched cohorts in the 12 months after index. No significant differences in baseline characteristics were found between the novel initiator patient subsets. ATX-indexed novel initiators had significantly longer persistence to index medication [mean (standard deviation; SD) days: 222.0 (133.9) vs 203.2 (135.0), P = 0.029) but higher switching rates (8.8 vs 5.5 %, P = 0.045) than LA-MPH-indexed novel initiators. The total ATX-indexed cohort required more prescriptions [any medication; mean (SD): 20.9 (11.5) vs 15.7 (9.0), P < 0.001] and outpatient visits [mean (SD): 10.1 (6.3) vs 8.3 (5.3), P < 0.001], and incurred significantly higher total median healthcare costs (€1144 vs €541, P < 0.001) versus matched LA-MPH patients. These real-world data indicate that, among children/adolescents with ADHD in Germany, ATX-indexed patients may require more prescriptions and physician visits, and incur higher total healthcare costs, than matched LA-MPH patients.

Summary of the 10th International Conference on Human Herpesviruses-6 and -7 (HHV-6A, -6B, and HHV-7).

Science.gov (United States)

Komaroff, Anthony L; Boeckh, Michael; Eliason, Eva; Phan, Tuan; Kaufer, Benedikt B

2018-04-01

The 10th International Conference on Human herpesviruses-6 and -7 (HHV-6A, HHV-6B, and HHV-7) was held at the Freie Universität, Berlin, Germany from July 23-26, 2017. It attracted more than 130 basic, translational and clinical scientists from 19 countries. Important new information was presented regarding: the biology of HHV-6A and -6B; the biology and epidemiology of inherited chromosomally integrated HHV-6A and -6B; improved diagnostic tests; animal models for and animal viruses with similarities to HHV-6A, -6B, and -7; established and possible disease associations; and new treatment strategies. Here, we summarize work presented at the meeting that is of particular interest. © 2017 Wiley Periodicals, Inc.

Germany as an energy-producing country - quo vadis?

International Nuclear Information System (INIS)

Rauscher, K.

2003-01-01

Secure, sufficient electricity supplies available at any time, as guaranteed in Germany, are vital to the existence of our modern society. Under the conditions of deregulated markets, it must continue to be possible in Germany to offer reliable, economical and non-polluting energy supplies. These three factors should enjoy equal importance in energy policy decisions in the interest of sustainability. The skewed balance caused by political preferences as experienced at the present time can jeopardize the general objective of optimization of the three factors in the long run. As in no other country, the power industry in Germany had to make a considerable adaptation effort, inter alia, because of market deregulation, airborne pollutant reduction, and agreements on the operating life of existing nuclear power plants. Other problems are likely to arise in the near future, e.g. in connection with emission trading. The power industry is willing and able to solve these future problems. This is true in particular of the expected replacement of power plants of approx. 40 000 MW generating capacity in Germany, where the European framework must be taken into account with a replacement requirement of approx. 200 000 MW. This implies investments of euro 50 billion in Germany alone, which can be made only if there is sufficient security in planning for the operators of power plants. The choice of efficient and economically viable power generation technologies must be possible in this respect. (orig.) [de

Cluster-to-cluster transformation among Au6, Au8 and Au11 nanoclusters.

Science.gov (United States)

Ren, Xiuqing; Fu, Junhong; Lin, Xinzhang; Fu, Xuemei; Yan, Jinghui; Wu, Ren'an; Liu, Chao; Huang, Jiahui

2018-05-22

We present the cluster-to-cluster transformations among three gold nanoclusters, [Au6(dppp)4]2+ (Au6), [Au8(dppp)4Cl2]2+ (Au8) and [Au11(dppp)5]3+ (Au11). The conversion process follows a rule that states that the transformation of a small cluster to a large cluster is achieved through an oxidation process with an oxidizing agent (H2O2) or with heating, while the conversion of a large cluster to a small one occurs through a reduction process with a reducing agent (NaBH4). All the reactions were monitored using UV-Vis spectroscopy and ESI-MS. This work may provide an alternative approach to the synthesis of novel gold nanoclusters and a further understanding of the structural transformation relationship of gold nanoclusters.

Maternal Employment and Childhood Overweight in Germany

OpenAIRE

Sophie-Charlotte Meyer

2015-01-01

A widespread finding among studies from the US and the UK is that maternal employment is correlated with an increased risk of child overweight, even in a causal manner, whereas studies from European countries obtain less conclusive results. As evidence for Germany is still scarce, the purpose of this study is to identify the effect of maternal employment on childhood overweight in Germany using two sets of representative micro data. Moreover, we explore potential underlying mechanisms that mi...

Climate protection policy. On Germany's pioneer role

International Nuclear Information System (INIS)

Kuebler, Knut

2014-01-01

After a downward trend of many years Germany's energy-related CO 2 emissions have risen again slightly over the past two years. This increase has prompted the federal government to initiate a new climate protection action campaign. After almost 30 years of experience in the field of climate protection policy there is every reason for Germany to be more consistent in using its political scope to act on the unrestrained increase in global greenhouse gas emissions.

The outlook for natural gas in Germany

International Nuclear Information System (INIS)

Bergmann, B.

1993-01-01

In a generally stagnant energy market, gas will be the energy with the highest growth rate in Germany, especially because of its steadily rising shares in the residential and commercial sector. In western Germany there is to be accepted that the demand forecasts, which were raised from one conference to the next, have passed their zenith. Great uncertainty exists as regards the future use of gas for power generation. In the absence of any significant expansion of this market sector, which is considered rather improbable in western Germany, it can be stated that anticipated gas demand up to the year 2005 is already covered by existing import contracts and scheduled domestic production. The picture is completely different in eastern Germany, where a doubling of consumption is quite feasible. To achieve the requisite diversification of supplies, substantial additional imports from western sources will have to be contracted. Russia can and should remain eastern Germany's main supplier in the long run, but Russian deliveries must be placed on a reliable, long-term contractual basis. As far as new gas projects are concerned, deliveries from Norway, to a limited extent from the United Kingdom and above all as part of the new Russian export initiative are under discussion. Generally speaking, transit will be an increasingly significant issue, especially for additional supplies from Russia. The efficiency and reliability of gas marketing companies will become far more important in an environment characterised by growing uncertainties. The reliable customer offering a dependable market outlet will be increasingly sought. With energy prices likely to increase only slightly, the management of uncertainties and the safeguarding of economic driving forces will be the main challenge facing our supply projects. 15 figs

[Surgery for benign goiter in Germany: fewer operations, changed resectional strategy, fewer complications].

Science.gov (United States)

Dralle, H; Stang, A; Sekulla, C; Rusner, C; Lorenz, K; Machens, A

2014-03-01

The increase of certain operations in the wake of the introduction of the German Diagnosis-Related Groups (G-DRG) system rekindled debate on the risk-benefit profile of what is widely being perceived as a too high number of thyroidectomies for benign goiter in Germany. The numbers of thyroidectomy for benign goiter from 2005-2011 were obtained from the Federal Bureau of Statistics ("Statistisches Bundesamt"). For the purpose of the study, the following operation and procedure key (OPS) codes were selected: hemithyroidectomy (OPS code 5-061); partial thyroid resection (OPS code 5-062); total thyroidectomy (OPS code 5-063); and thyroid surgeries via sternotomy (OPS code 5-064). The rates of permanent hypoparathyroidism and vocal cord palsy were calculated based on two prospective multicenter evaluation studies conducted in 1998-2001 (PETS 1) and 2010-2013 (PETS 2) in Germany. Between 2005 and 2011, the number of thyroidectomies for benign thyroid goiter decreased by 8 %, and the age-standardized surgery rate decreased by 6 % in men (2005: 599 per 1 million; 2011: 565 per 1 million) and 11 % in women (2005: 1641 per 1 million; 2011: 1463 per 1 million). At the same time, the rates of partial and subtotal thyroidectomy decreased by 59 % in men and 64 % in women, whereas the rates of hemithyroidectomy and total thyroidectomy increased by 65 % (113 %) in men and 42 % (97 %) in women. Despite a greater proportion of thyroidectomies over time, the approximated rates for postoperative hypoparathyroidism were reduced from 2.98 to 0.83 % and for postoperative vocal cord palsy from 1.06 to 0.86 %. Irrespective of that decline, either complication was more frequent after total than after subtotal thyroidectomy. The total number of thyroid surgeries due to benign goiter has decreased substantially in Germany from 2005 through 2011. Despite changes in the resectional strategy with an increase in the total number thyroidectomies and a decrease of subtotal

Educational Systems and Rising Inequality: Eastern Germany after Unification

Science.gov (United States)

von Below, Susanne; Powell, Justin J. W.; Roberts, Lance W.

2013-01-01

Educational systems considerably influence educational opportunities and the resulting social inequalities. Contrasting institutional regulations of both structures and contents, the authors present a typology of educational system types in Germany to analyze their effects on social inequality in eastern Germany after unification. After 1990, the…

Phylogenetic diversity, antimicrobial susceptibility and virulence gene profiles of Brachyspira hyodysenteriae isolates from pigs in Germany.

Directory of Open Access Journals (Sweden)

Jessica Joerling

Full Text Available Swine dysentery (SD is an economically important diarrheal disease in pigs caused by different strongly hemolytic Brachyspira (B. species, such as B. hyodysenteriae, B. suanatina and B. hampsonii. Possible associations of epidemiologic data, such as multilocus sequence types (STs to virulence gene profiles and antimicrobial susceptibility are rather scarce, particularly for B. hyodysenteriae isolates from Germany. In this study, B. hyodysenteriae (n = 116 isolated from diarrheic pigs between 1990 and 2016 in Germany were investigated for their STs, susceptibility to the major drugs used for treatment of SD (tiamulin and valnemulin and genes that were previously linked with virulence and encode for hemolysins (tlyA, tlyB, tlyC, hlyA, BHWA1_RS02885, BHWA1_RS09085, BHWA1_RS04705, and BHWA1_RS02195, outer membrane proteins (OMPs (bhlp16, bhlp17.6, bhlp29.7, bhmp39f, and bhmp39h as well as iron acquisition factors (ftnA and bitC. Multilocus sequence typing (MLST revealed that 79.4% of the isolates belonged to only three STs, namely ST52 (41.4%, ST8 (12.1%, and ST112 (25.9% which have been observed in other European countries before. Another 24 isolates belonged to twelve new STs (ST113-118, ST120-123, ST131, and ST193. The temporal distribution of STs revealed the presence of new STs as well as the regular presence of ST52 over three decades (1990s-2000s. The proportion of strains that showed resistance to both tiamulin und valnemulin (39.1% varied considerably among the most frequent STs ranging from 0% (0/14 isolates resistant in ST8 isolates to 46.7% (14/30, 52.1% (25/48, and 85.7% (6/7 in isolates belonging to ST112, ST52, and ST114, respectively. All hemolysin genes as well as the iron-related gene ftnA and the OMP gene bhlp29.7 were regularly present in the isolates, while the OMP genes bhlp17.6 and bhmp39h could not be detected. Sequence analysis of hemolysin genes of selected isolates revealed co-evolution of tlyB, BHWA1_RS02885, BHWA1_RS

Phylogenetic diversity, antimicrobial susceptibility and virulence gene profiles of Brachyspira hyodysenteriae isolates from pigs in Germany

Science.gov (United States)

Joerling, Jessica; Barth, Stefanie A.; Schlez, Karen; Willems, Hermann

2018-01-01

Swine dysentery (SD) is an economically important diarrheal disease in pigs caused by different strongly hemolytic Brachyspira (B.) species, such as B. hyodysenteriae, B. suanatina and B. hampsonii. Possible associations of epidemiologic data, such as multilocus sequence types (STs) to virulence gene profiles and antimicrobial susceptibility are rather scarce, particularly for B. hyodysenteriae isolates from Germany. In this study, B. hyodysenteriae (n = 116) isolated from diarrheic pigs between 1990 and 2016 in Germany were investigated for their STs, susceptibility to the major drugs used for treatment of SD (tiamulin and valnemulin) and genes that were previously linked with virulence and encode for hemolysins (tlyA, tlyB, tlyC, hlyA, BHWA1_RS02885, BHWA1_RS09085, BHWA1_RS04705, and BHWA1_RS02195), outer membrane proteins (OMPs) (bhlp16, bhlp17.6, bhlp29.7, bhmp39f, and bhmp39h) as well as iron acquisition factors (ftnA and bitC). Multilocus sequence typing (MLST) revealed that 79.4% of the isolates belonged to only three STs, namely ST52 (41.4%), ST8 (12.1%), and ST112 (25.9%) which have been observed in other European countries before. Another 24 isolates belonged to twelve new STs (ST113-118, ST120-123, ST131, and ST193). The temporal distribution of STs revealed the presence of new STs as well as the regular presence of ST52 over three decades (1990s–2000s). The proportion of strains that showed resistance to both tiamulin und valnemulin (39.1%) varied considerably among the most frequent STs ranging from 0% (0/14 isolates resistant) in ST8 isolates to 46.7% (14/30), 52.1% (25/48), and 85.7% (6/7) in isolates belonging to ST112, ST52, and ST114, respectively. All hemolysin genes as well as the iron-related gene ftnA and the OMP gene bhlp29.7 were regularly present in the isolates, while the OMP genes bhlp17.6 and bhmp39h could not be detected. Sequence analysis of hemolysin genes of selected isolates revealed co-evolution of tlyB, BHWA1_RS02885, BHWA1_RS

Study on the Electrochemical Property of Microporous Cobalt Phosphite[Co_11(HPO_3)_8(OH)_6

International Nuclear Information System (INIS)

Lee, Dong Heon; Kang, Myunggoo; Jung, Hyun; Paek, Seung-Min

2016-01-01

Crystalline microporous cobalt phosphite, Co_11(HPO_3)_8(OH)_6, was prepared via facile hydrothermal route without the use of any templates or surfactants. The cobalt chloride hexahydrate (CoCl_2·6H_2O) and sodium hypophosphite monohydrate (NaH_2PO_2·H_2O) were employed as reactants, and sodium bicarbonate(NaHCO_3) was added to adjust the pH. The resultant Co_11(HPO_3)_8(OH)_6 shows dumbbell-like shape witha size of several micrometers. The obtained materials were characterized by X-ray diffraction (XRD), Fourier transform infrared (FT-IR) spectroscopy, thermal gravimetric analysis (TGA), field-emission scanning electron microscopy (FE-SEM), and energy dispersive spectrometry (EDS). The Co_11(HPO_3)_8(OH)_6 is applied as electrochemical energy storage electrode material because of its unique microporous nature. Different aqueous electrolytes (LiOH, NaOH, and KOH) have been tested in order to study the effect of electrolyte cations on electrochemical behavior. To investigate the capacity and stability of Co_11(HPO_3)_8(OH)_6 electrode, cyclic voltammetry (CV), galvanostatic charge-discharge (GC), and cycle stability were performed in aqueous electrolytes with different cations at room temperature. We found that the electrochemical behavior of these materials is strongly dependent on the species of electrolyte cations (Li"+,Na"+, and K"+).

Cellular telephone use among primary school children in Germany

International Nuclear Information System (INIS)

Boehler, Eva; Schuez, Joachim

2004-01-01

Background: There is some concern about potential health risks of cellular telephone use to children. We assessed data on how many children own a cellular telephone and on how often they use it in a population-based sample. Methods: We carried out a cross-sectional study among children in their fourth elementary school year, with a median-age of 10 years. The study was carried out in Mainz (Germany), a city with about 200,000 inhabitants. The study base comprised all 37 primary schools in Mainz and near surroundings. Altogether, 1933 children from 34 primary schools took part in the survey (participation rate of 87.8%). Results: Roughly a third of all children (n = 671, 34.7%) reported to own a cellular telephone. Overall, 119 (6.2%) children used a cellular telephone for making calls at least once a day, 123 (6.4%) used it several times a week and 876 (45.3%) children used it only once in a while. The remaining 805 (41.6%) children had never used a cellular telephone. The probability of owning a cellular telephone among children was associated with older age, being male, having no siblings, giving full particulars to height and weight, more time spent watching TV and playing computer games, being picked up by their parents from school by car (instead of walking or cycling) and going to bed late. The proportion of cellular telephone owners was somewhat higher in classes with more children from socially disadvantaged families. Conclusions: Our study shows that both ownership of a cellular telephone as well as the regular use of it are already quite frequent among children in the fourth grade of primary school. With regard to potential long-term effects, we recommend follow-up studies with children

41 CFR 51-6.8 - Deletion of items from the Procurement List.

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Deletion of items from...-PROCUREMENT PROCEDURES § 51-6.8 Deletion of items from the Procurement List. (a) When a central nonprofit... shall notify the Committee staff immediately. Before reaching a decision to request a deletion of an...

Upconversion based spectral imaging in 6 to 8 μm spectral regime

DEFF Research Database (Denmark)

Junaid, Saher; Tidemand-Lichtenberg, Peter; Pedersen, Christian

2017-01-01

Spectral imaging in the 6 to 8μm range has great potential for medical diagnostics. Here a novel technique based on frequency upconversion of the infrared images to the near visible for subsequent acquisition using a Si-CCD camera is investigated. The upconversion unit consists of an AgGaS2 crystal...

Physical activity during work, transport and leisure in Germany--prevalence and socio-demographic correlates.

Science.gov (United States)

Wallmann-Sperlich, Birgit; Froboese, Ingo

2014-01-01

This study aimed 1) to provide data estimates concerning overall moderate- and vigorous-intensity physical activity (MVPA) as well as MVPA during work, transport and leisure in Germany and 2) to investigate MVPA and possible associations with socio-demographic correlates. A cross-sectional telephone survey interviewed 2248 representative participants in the age of 18-65 years (1077 men; 42.4 ± 13.4 years; body mass index: 25.3 ± 4.5 kg • m(-2)) regarding their self-reported physical activity across Germany. The Global Physical Activity Questionnaire was applied to investigate MVPA during work, transport and leisure and questions were answered concerning their demographics. MVPA was stratified by gender, age, body mass index, residential setting, educational and income level. To identify socio-demographic correlates of overall MVPA as well as in the domains, we used a series of linear regressions. 52.8% of the sample achieved physical activity recommendations (53.7% men/52.1% women). Overall MVPA was highest in the age group 18-29 years (p importance of a comprehensive view on physical activity engagement according to the different physical activity domains and discloses a need for future physical activity interventions that consider socio-demographic variables, residential setting as well as the physical activity domain in Germany.

Wind power in Germany - a success story

International Nuclear Information System (INIS)

Weller, T.

1996-01-01

The successful introduction of wind power to the electric power industry in the Federal Republic of Germany is described using graphic representations to illustrate the industry's growth over the last twenty years. The history of the wind market is discussed, together with the importance of stakeholders as a way of funding the industry. The author concludes that public support for environmentally sensitive power generation was the key factor leading to the success of the wind power industry in Germany. (UK)

Housing Markets in Austria, Germany and Switzerland

OpenAIRE

Martin Schneider; Karin Wagner

2015-01-01

Running counter to the sharp rise in house prices and housing wealth observed since the mid- 1990s in the vast majority of European countries, real house prices in Germany and Austria were going down in this period and did not start to rise until 2010 or 2007, respectively. This reflects national idiosyncracies in housing markets and motivated the discussion of relevant peculiarities in, and similarities among, Austria and Germany as well as Switzerland. Among the most important structural fe...

Structural phase transitions in BaMo6S8: Evidence for an incommensurate phase

International Nuclear Information System (INIS)

Jorgensen, J.D.; Hinks, D.G.; Hatch, D.M.; Putnam, R.M.

1986-01-01

The structure of BaMo 6 S 8 has been studied over the temperature range 19 K to 573 K by time-of-flight neutron powder diffraction. Below 175 K the data can be suitably refined in a triclinic, P1, cell with volume equal to the rhombohedral, R3, cell common to most Chevrel-phase structures. At temperatures immediately above 175 K, the rhombohedral, R3, Bragg peaks are broadened by satellite reflections which appear to be identical to those recently observed at low temperature in PbMo 6 S 8 and SnMo 6 S 8 . An abrupt change in the sign of the temperature dependence of the hexagonal c axis (∂c/∂T) signals the transition to an undistorted rhombohedral, R3, structure at temperatures above about 350 K. An extended Landau theory determines both continuous and discontinuous transitions from R3 induced by a single order parameter. Analysis of the order parameters inducing commensurate transitions imposes symmetry restrictions on the atomic displacements in the lower symmetry phases. The assumption of an R3 commensurate phase is not consistent with the bond lengths obtained for the distortions to the P1 (or P1) phase for any of the possible cells preserving order parameters. Thus the phase immediately above 175 K cannot be a commensurate R3 structure. This is consistent with experimental evidence. 25 refs., 11 figs., 8 tabs

Radon anomalies precursory to the 2003 Mw = 6.8 Chengkung and 2006 Mw = 6.1 Taitung earthquakes in Taiwan

International Nuclear Information System (INIS)

Kuo, T.; Lin, C.; Fan, K.; Chang, G.; Lewis, C.; Han, Y.; Wu, Y.; Chen, W.; Tsai, C.

2009-01-01

Contrary to the normally observed increase in groundwater radon that occurs prior to earthquakes, we have measured anomalous decreases in radon concentration prior to the 2003 M W = 6.8 Chengkung and 2006 M W = 6.1 Taitung earthquakes that occurred within a 55 km radius from the Antung D1 monitoring well in eastern Taiwan. The v-shaped pattern of radon anomalies recognized at Antung is valuable for detecting the aseismic strain precursory to potentially disastrous earthquakes in a fractured aquifer surrounded by ductile aquitard in seismotectonic environments in this area.

Tax wedge in Croatia, Belgium, Estonia, Germany and Slovakia

Directory of Open Access Journals (Sweden)

Ana Gabrilo

2016-06-01

Full Text Available The aim of this paper is to analyse the taxation of labour income in Croatia, Belgium,Estonia, Germany and Slovakia. Having presented an outline of tax system rules, the paper shows the decomposition of the net average tax wedge for different family types and different income levels based on the OECD methodology. The results show that all observed countries apply a progressive tax schedule, apart from Germany where taxation for higher gross wages is not progressive due to a  cap on the SIC base. When it comes to a taxpayer earning an average gross wage, a Croatian single worker without children has the lowest tax burden, followed by Estonia, Slovakia, Germany and Belgium. However, as regards taxpayers earning 400% of AGW, Estonia has the smallest tax wedge, followed by Slovakia, Germany, Croatia and Belgium. Similar results are obtained by analyzing the tax wedge for couples with two children where one spouse is out of work.

Rewriting Germany's nuclear law

International Nuclear Information System (INIS)

Roser, T.

1992-01-01

In Germany, the private use of nuclear energy for peaceful uses is strictly regulated by a Nuclear Energy Act. Since its enactment back in 1959, this legislation has been overhauled five times - most recently in 1985. Now Klaus Toepfer, Germany's Federal Minister for the Environment, Protection of Nature, and Nuclear Safety, has set out to revise the Act for the sixth time. The present draft bill is intended to reorganise the back end of the nuclear fuel cycle; eliminate public promotion of nuclear power; clarify points of legal dispute. Of the draft bill's three aims, the last two are more parochial. The real novelty lies in the changes to the rules for the back end of the fuel cycle. First, the Federal Government proposes to abandon the priority given to spent fuel recycling. In future, direct disposal will be an equivalent option, and waste avoidance will have top priority. Intimately linked to the back end proposal is the Government's plan to load on the shoulders of nuclear operators the full responsibility for building and operating repositories for the final disposal of nuclear waste. The third aspect of Government's back end plans concerns decommissioning. At present, operators accumulate provisions over the plant lifetime, which for that purpose is estimated at 19 years. The provisions vary from plant to plant but are generally around DM1 billion and are tax free. Under the proposed regulations, this sum must be available from the first day of operation to cover the case of an early shutdown. In practice, this will increase the initial investment for a nuclear power plant in Germany by 10-20% and so make nuclear power less competitive. (author)

Nuclear power in Germany

International Nuclear Information System (INIS)

Schaefer, A.

1990-01-01

I want to give some ideas on the situation of public and utility acceptance of nuclear power in the Federal Republic of Germany and perhaps a little bit on Europe. Let me start with public perception. I think in Germany we have a general trend in the public perception of technology during the last decade that has been investigated in a systematic manner in a recent study. It is clear that the general acceptance of technology decreased substantially during the last twenty years. We can also observe during this time that aspects of the benefits of technology are much less reported in the media, that most reporting by the media now is related to the consequences of technologies, such as negative environmental consequences. hat development has led to a general opposition against new technological projects, in particular unusual and large. That trend is related not only to nuclear power, we see it also for new airports, trains, coal-fired plants. here is almost no new technological project in Germany where there is not very strong opposition against it, at least locally. What is the current public opinion concerning nuclear power? Nuclear power certainly received a big shock after Chernobyl, but actually, about two thirds of the German population wants to keep the operating plants running. Some people want to phase the plants out as they reach the end-of-life, some want to substitute newer nuclear technology, and a smaller part want to increase the use of nuclear power. But only a minority of the German public would really like to abandon nuclear energy

Nuclear third party liability in Germany

International Nuclear Information System (INIS)

Raetzke, Christian

2016-01-01

The German system of nuclear third party liability has always been, and arguably still is, the object of considerable interest in the international nuclear law community. This may seem surprising since Germany adheres to the Paris Convention and is therefore a party to a community of 15 states all following the same principles enshrined in this Convention. In fact, when implementing the PC, Germany chose the approach ensuring the most literal adherence to the PC's principles: it adopted the PC in its entirety, thus directly transposing the PC text into binding German law, instead of enacting a national law derived from, but not literally translating, the PC. At the same time, perhaps no other nation has made use of the options, choices and margins offered or abandoned by the PC to the national legislators, or kept in store by way of a reservation at signature of the Convention, in such an extended manner, testing - and as has even been contended in the past: stressing - the boundaries of the PC system. Unlimited liability introduced in 1985, the highest financial security of any PC state (EUR 2.5 billion), unlimited territorial scope combined with the principle of reciprocity and liability of German operators even in the force majeure cases of Article 9 of the PC are probably the most interesting decisions made by Germany in this context, established in the Atomic Energy Act (Atomgesetz). These choices betray a certain tendency of the German government to give the greatest possible benefit to victims, and in parallel to achieve a 'normalisation' of the nuclear liability regime, without stifling the industry. Within the compromise underlying the international nuclear liability regime - enabling the nuclear industry to create and sustain an energy sector highly relevant for national electricity production on the one hand and protecting potential victims on the other - Germany has more and more shifted the balance, as far as practically possible, to the

Final storage in Germany. Who is interested?

International Nuclear Information System (INIS)

Kuehn, K.

2002-01-01

The final storage of radioactive waste and spent fuel in Germany - who, in Germany, has any interest in this subject, especially now that the new Atomic Energy Act has been adopted, and who is going to read this article? The author, Professor Klaus Kuehn, examines this question, analyzing in his contribution the current situation and the points of view of those who may be interested in this topic. In Prof. Kuehn's opinion, the addresses in particular are these: - the federal government, - the opposition in the federal parliament, - the federal states, - the Federal Ministry for the Environment, - the Federal Ministry for Research, - the Federal Ministry of Economics, - the Federal Office for Radiation Protection, - the operators of nuclear power plants, - the Working Group Elaborating Procedures for Selecting Repository Sites (AkEnd). Klaus Kuehn concludes that there is little interest at the present time in the subject of Final Storage in Germany, for reasons explained in detail which result both from the political constellation and from existing constraints. (orig.) [de

AREVA Germany. International competence in nuclear technology

International Nuclear Information System (INIS)

Graeber, Ulrich

2011-01-01

AREVA NP was created in 2001 by the merger of the French nuclear technology specialist Framatome with the nuclear sector of Siemens. The company is headquartered in Paris and has regional subsidiaries in Germany and the United States. The joint venture's strength lies in its all-round competence in nuclear power plants, from reactor development to power plant services and modernization of operating plants, design and production of fuel assemblies and turn-key construction of nuclear power reactors. Major core competences are located in Germany including the test facilities which are unique in the entire group as well as electrical engineering and instrumentation and control systems. AREVA NP is part of the globally acting AREVA group which pursues a unique integrated business model. The concept covers the entire nuclear fuel cycle from uranium mining to reprocessing used fuel assemblies. At present, AREVA has 48,000 employees worldwide, of which 5,700 are Germany-based. (orig.)

Peculiarities of transformation processes in East Germany

Directory of Open Access Journals (Sweden)

Marion Dathe

2011-03-01

Full Text Available The process of socio-economic transformation of East German lands after the German reunification in 1990 is analyzed, the term "transformation" in frames of planned and market economies is defined. The author studies the historical determinants of the transformation process in Germany. German economic and industrial history in context of the driving forces and their social values, as well as the properties of the planning and economic systems that underlie the transformation of East German mentality, are considered. Further analysis is connected with economic, social and political components of the East German transformation process, "the dominance of the West", the collapse of the Council for Mutual Economic Assistance, privatization etc. Finally, the outcome of already traversed path of transformation of East Germany is considered. It is concluded, that the transformation process is not only historically conditioned situations of both the merging parties in the case of Germany, but also the positive or negative perception of its results and the motivation for its further implementation.

Environmental stress in German forests; assessment of critical deposition levels and their exceedances and meteorological stress for crown condition monitoring sites in Germany

NARCIS (Netherlands)

Klap, J.M.; Reinds, G.J.; Bleeker, A.; Vries, de W.

2000-01-01

Site-specific estimations of meteorological stress and atmospheric deposition were made for the systematic 8 x 8 km2 forest condition monitoring network in Germany for the years 1987-1995. Winter cold and late frost were important temperature stress variables and relative transpiration was a good

Prevalence of weather sensitivity in Germany and Canada

Science.gov (United States)

Mackensen, Sylvia; Hoeppe, Peter; Maarouf, Abdel; Tourigny, Pierre; Nowak, Dennis

2005-01-01

Several studies have shown that atmospheric conditions can affect well-being or disease, and that some individuals seem to be more sensitive to weather than others. Since epidemiological data on the prevalence of weather-related health effects are lacking, two representative weather sensitivity (WS) surveys were conducted independently in Germany and Canada. The objectives of this paper are: (1) to identify the prevalence of WS in Germany and Canada, (2) to describe weather-related symptoms and the corresponding weather conditions, and (3) to compare the findings in the two countries. In Germany 1,064 citizens (age >16 years) were interviewed in January 2001, and in Canada 1,506 persons (age >18 years) were interviewed in January 1994. The results showed that 19.2% of the German population thought that weather affected their health “to a strong degree,” 35.3% that weather had “some influence on their health” (sum of both = 54.5% weather sensitive), whereas the remaining 45.5% did not consider that weather had an effect on their health status. In Canada 61% of the respondents considered themselves to be sensitive to the weather. The highest prevalence of WS (high + some influence) in Germans was found in the age group older than 60 years (68%), which was almost identical in the Canadian population (69%). The highest frequencies of weather-related symptoms were reported in Germany for stormy weather (30%) and when it became colder (29%). In Canada mainly cold weather (46%), dampness (21%) and rain (20%) were considered to affect health more than other weather types. The most frequent symptoms reported in Germany were headache/migraine (61%), lethargy (47%), sleep disturbances (46%), fatigue (42%), joint pain (40%), irritation (31%), depression (27%), vertigo (26%), concentration problems (26%) and scar pain (23%). Canadian weather-sensitive persons reported colds (29%), psychological effects (28%) and painful joints, muscles or arthritis (10%). In Germany 32

The Marketisation of Guidance Services in Germany, France and Britain.

Science.gov (United States)

Rees, Teresa; Bartlett, Will; Watts, A. G.

1999-01-01

Compares developments in Britain, France, and Germany, focusing on the trends toward marketing adult career guidance services. Describes how Germany's centralized system and the quasi-market based system in France might apply in Britain. (JOW)

The DFG Viewer for Interoperability in Germany

Directory of Open Access Journals (Sweden)

Ralf Goebel

2010-02-01

Full Text Available This article deals with the DFG Viewer for Interoperability, a free and open source web-based viewer for digitised books, and assesses its relevance for interoperability in Germany. First the specific situation in Germany is described, including the important role of the Deutsche Forschungsgemeinschaft (German Research Foundation. The article then moves on to the overall concept of the viewer and its technical background. It introduces the data formats and standards used, it briefly illustrates how the viewer works and includes a few examples.

An examination of coping styles and expectations for whiplash injury in Germany: comparison with Canadian data.

Science.gov (United States)

Ferrari, Robert; Pieschl, Stephanie

2011-09-01

Cross-sectional cohort study: to examine concurrent expectations and coping style for whiplash injury in injury-naive subjects in Germany. Studies suggest the recovery rate from whiplash injury may be faster in Germany than in Canada. Canadians have a high expectation for chronic pain following whiplash injury and Germans do not. Expectation of recovery not only predicts recovery in whiplash victims but is also known to correlate with coping style. The Vanderbilt Pain Management Inventory was administered to university students and staff in Germany. Subjects who had not yet experienced whiplash injury were given a vignette concerning a neck sprain (whiplash injury) in a motor vehicle collision and were asked to indicate how likely they were to have thoughts or behaviours indicated in the coping style questionnaire. Subjects also completed expectation questionnaires regarding whiplash injury. Sixteen percent of subjects held an expectation of chronic neck or back pain after whiplash injury. The mean active coping style score was 27.4±3.6 (40 is the maximum score for active coping). The mean passive coping style score was 27.0±6.3 (50 is the maximum score for passive coping). Coping style scores and patterns were not different from those previously observed in Canadian studies, but there was no correlation between expectations and coping style among German subjects, a finding that differs from Canadian studies. Although expectations and coping styles may interact or be co-modifiers in the outcomes of whiplash injury in Canadian whiplash victims, in Germany, despite having similar coping styles to Canadians, the lack of expectation for chronic pain may be protective from the effect of passive coping styles. Further studies of coping style as an aetiologic factor in the chronic whiplash syndrome are needed.

Lattice instability in the non-superconducting compound EuMo6S8

International Nuclear Information System (INIS)

Baillif, R.; Junod, A.; Lachal, B.; Muller, J.; Yvon, K.

1981-01-01

Electrical resistivity and specific heat measurements were performed on bulk Eusub(1.1)Mo 6 S 8 together with low-temperature X-ray powder diffractometry. These investigations revealed a structural phase transition (occuring at 109 K) from the room-temperature rhombohedral structure to a low-temperature triclinic distorted structure in which the compound exhibits a non-metallic behavior. (author)

Structure and redox properties of 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane (CL-20 adsorbed on a silica surface. M05 computational study

Directory of Open Access Journals (Sweden)

Liudmyla K. Sviatenko

2016-03-01

Full Text Available The cluster approximation was applied at M05/tzvp level to model adsorption of 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane (CL-20 on (001 surface of α-quartz. Structures of the obtained CL-20–silica complexes confirm close to parallel orientation of the nitrocompound toward surface. The binding between CL-20 and silica surface was analyzed and bond energies were calculated applying the atoms in molecules (AIM method. Hydrogen bonds were found to significantly contribute in adsorption energy. An attaching of electron leads to significant deviation from coplanarity in complexes and to strengthening of hydrogen bonding. Redox properties of adsorbed CL-20 were compared with those of gas-phase and hydrated species by calculation of electron affinity, ionization potential, reduction Gibbs free energy, oxidation Gibbs free energy, reduction and oxidation potentials. It was shown that adsorbed CL-20 has lower ability to redox transformation as compared with hydrated one.

Overexpressed HDAC8 in cervical cancer cells shows functional redundancy of tubulin deacetylation with HDAC6.

Science.gov (United States)

Vanaja, G R; Ramulu, Hemalatha Golaconda; Kalle, Arunasree M

2018-05-02

Histone deacetylases (HDACs) are involved in epigenetic gene regulation via deacetylation of acetylated lysine residues of both histone and non-histone proteins. Among the 18 HDACs identified in humans, HDAC8, a class I HDAC, is best understood structurally and enzymatically. However, its precise subcellular location, function in normal cellular physiology, its protein partners and substrates still remain elusive. The subcellular localization of HDAC8 was studied using immunofluorescence and confocal imaging. The binding parterns were identified employing immunoprecipitation (IP) followed by MALDI-TOF analysis and confirmed using in-silico protein-protein interaction studies, HPLC-based in vitro deacetylation assay, intrinsic fluorescence spectrophotometric analysis, Circular dichroism (CD) and Surface Plasmon Resonance (SPR). Functional characterization of the binding was carried out using immunoblot and knockdown by siRNA. Using one way ANOVA statistical significance (n = 3) was determined. Here, we show that HDAC8 and its phosphorylated form (pHDAC8) localized predominantly in the cytoplasm in cancerous, HeLa, and non-cancerous (normal), HEK293T, cells, although nucleolar localization was observed in HeLa cells. The study identified Alpha tubulin as a novel interacting partner of HDAC8. Further, the results indicated binding and deacetylation of tubulin at ac-lys40 by HDAC8. Knockdown of HDAC8 by siRNA, inhibition of HDAC8 and/or HDAC6 by PCI-34051 and tubastatin respectively, cell-migration, cell morphology and cell cycle analysis clearly explained HDAC8 as tubulin deacetylase in HeLa cells and HDAC6 in HEK 293 T cells. HDAC8 shows functional redundancy with HDAC6 when overexpressed in cervical cancer cells, HeLa, and deacetylaes ac-lys40 of alpha tubulin leading to cervical cancer proliferation and progression.

Prevalence of rosacea in the general population of Germany and Russia - The RISE study.

Science.gov (United States)

Tan, J; Schöfer, H; Araviiskaia, E; Audibert, F; Kerrouche, N; Berg, M

2016-03-01

There is an unmet need for general population-based epidemiological data on rosacea based on contemporary diagnostic criteria and validated population survey methodology. To evaluate the prevalence of rosacea in the general population of Germany and Russia. General population screening was conducted in 9-10 cities per country to ensure adequate geographic representation. In Part I of this two-phase study, screening of a representative sample of the general population (every fifth person or every fifth door using a fixed-step procedure on a random route sample) was expedited with use of a questionnaire and algorithm based on current diagnostic criteria for rosacea. Of the subjects that screened positive in the initial phase, a randomly selected sample (every third subject) t`hen underwent diagnostic confirmation by a dermatologist in Part II. A total of 3052 and 3013 subjects (aged 18-65 years) were screened in Germany and Russia respectively. Rosacea prevalence was 12.3% [95%CI, 10.2-14.4] in Germany and 5.0% [95%CI, 2.8-7.2] in Russia. The profile of subjects with rosacea (75% women; mean age of 40 years; mainly skin phototype II or III, majority of subjects with sensitive facial skin) and subtype distribution were similar. Overall, 18% of subjects diagnosed with rosacea were aged 18-30 years. Over 80% were not previously diagnosed. Within the previous year, 47.5% of subjects had received no rosacea care and 23.7% had received topical and/or systemic drugs. Over one-third (35% Germany, 43% Russia) of rosacea subjects reported a moderate to severe adverse impact on quality of life. Rosacea is highly prevalent in Germany (12.3%) and Russia (5.0%). The demographic profile of rosacea subjects was similar between countries and the majority were previously undiagnosed. © 2016 The Authors. Journal of the European Academy of Dermatology and Venereology published by John Wiley & Sons Ltd on behalf of European Academy of Dermatology and Venereology.

Neuer Atheismus: New Atheism in Germany

Directory of Open Access Journals (Sweden)

Thomas Zenk

2012-06-01

Full Text Available Matthias Knutzen (born 1646 – died after 1674 was the first author we know of who self-identified as an atheist (Schröder 2010: 8. Before this, the term had solely been used pejoratively to label others. While Knutzen is almost completely forgotten now, authors such as Ludwig Feuerbach, Karl Marx, Friedrich Nietzsche, or Sigmund Freud are better remembered and might even be considered classic writers in the history of the atheist criticism of religion. Whatever may be said about the influence of any one of these authors, there is no doubt that Germany looks back on a notable history in this field. About a decade ago, Germany’s capital Berlin was even dubbed ‘the world capital of atheism’ by the American sociologist Peter L. Berger (2001: 195.Given this situation, I am bewildered by the expression ‘New Atheism’. Yet, undoubtedly, the term has become a catchphrase that is commonly used in the public discourse of several countries. The most prominent authors to be labelled ‘New Atheists’ are Richard Dawkins (The God Delusion, 2006, Daniel Dennett (Breaking the Spell: Religion as a Natural Phenomenon, 2006, Sam Harris (The End of Faith: Religion, Terror, and the Future of Reason, 2004, and Letter to a Christian Nation, 2006, and Christopher Hitchens (God Is Not Great: How Religion Poisons Every­thing, 2007. These authors and their books – all of them international bestsellers – have been intensely discussed around the world, including in Germany. In this paper, I intend to illuminate some of the characteristics and remarkable traits of the German discourse on the ‘New Atheism’. Here we can distinguish between two phases. The German media initially characterised ‘New Atheism’ as a rather peculiarly American phenomenon. However, it soon came to be understood to be a part of German culture as well.

Risk for latent and active tuberculosis in Germany.

Science.gov (United States)

Herzmann, Christian; Sotgiu, Giovanni; Bellinger, Oswald; Diel, Roland; Gerdes, Silke; Goetsch, Udo; Heykes-Uden, Helga; Schaberg, Tom; Lange, Christoph

2017-06-01

Few individuals that are latently infected with M. tuberculosis latent tuberculosis infection(LTBI) progress to active disease. We investigated risk factors for LTBI and active pulmonary tuberculosis (PTB) in Germany. Healthy household contacts (HHCs), health care workers (HCWs) exposed to M. tuberculosis and PTB patients were recruited at 18 German centres. Interferon-γ release assay (IGRA) testing was performed. LTBI risk factors were evaluated by comparing IGRA-positive with IGRA-negative contacts. Risk factors for tuberculosis were evaluated by comparing PTB patients with HHCs. From 2008-2014, 603 HHCs, 295 HCWs and 856 PTBs were recruited. LTBI was found in 34.5% of HHCs and in 38.9% of HCWs. In HCWs, care for coughing patients (p = 0.02) and longstanding nursing occupation (p = 0.04) were associated with LTBI. In HHCs, predictors for LTBI were a diseased partner (odds ratio 4.39), sexual contact to a diseased partner and substance dependency (all p < 0.001). PTB was associated with male sex, low body weight (p < 0.0001), alcoholism (15.0 vs 5.9%; p < 0.0001), glucocorticoid therapy (7.2 vs 2.0%; p = 0.004) and diabetes (7.8 vs. 4.0%; p = 0.04). No contact developed active tuberculosis within 2 years follow-up. Positive IGRA responses are frequent among exposed HHCs and HCWs in Germany and are poor predictors for the development of active tuberculosis.

Clinical significance of measurement of serum NO, IL-6 and IL-8 levels after treatment in patients with schizophrenia

International Nuclear Information System (INIS)

Gao Wanqin

2010-01-01

Objective: To study the significance of changes of serum NO, IL-6 and IL-8 levels after treatment in patients with schizophrenia. Methods: Serum IL-6, IL-8 (with RIA) and NO (with bio-chemistry) levels were determined in 37 patients with schizophrenia both before and after treatment as well as in 35 controls. Results: Before treatment, the serum IL-6, IL-8 levels in the patients were significantly higher than those in controls (P<0.01). While the serum NO levels were significantly lower (P<0.01). After six weeks' treatment, the levels of IL-6, IL-8 in the patients, though dropped markedly still remained significantly higher (P<0.05) than those in controls. The serum NO levels, though markedly increased after treatment, were still remained significantly lower than those in the controls (P<0.05). Conclusion: Serum NO, IL-6 and IL-8 levels were closely related to the diseases process of schizophrenia and were of prognostic values. (authors)

Two-proton pickup studies with the (6Li,8B) reaction

Energy Technology Data Exchange (ETDEWEB)

Weisenmiller, R.B.

1976-12-03

The (/sup 6/Li,/sup 8/B) reaction has been investigated on targets of /sup 26/Mg, /sup 24/Mg, /sup 16/O, /sup 13/C, /sup 12/C, /sup 11/B, /sup 10/B, and /sup 9/Be at a bombarding energy of 80.0 MeV, and on targets of /sup 16/O, /sup 12/C, /sup 9/Be, /sup 7/Li, and /sup 6/Li at a bombarding energy of 93.3 MeV. Only levels consistent with direct, single-step two-proton pickup reaction mechanisms were observed to be strongly populated. On T/sub z/ = 0 targets, the spectroscopic selectivity of this reaction resembles that of the analogous (p,t) reaction. Additionally, these data demonstrate the dominance of spatially symmetric transfer of the two protons. On T/sub z/ greater than 0 targets the (/sup 6/Li,/sup 8/B) reaction was employed to locate two previously unreported levels (at 7.47 +- 0.05 MeV and 8.86 +- 0.07 MeV) in the T/sub z/ = 2 nuclide /sup 24/Ne and to establish the low-lying 1p-shell states in the T/sub z/ = /sup 3///sub 2/ nuclei /sup 11/Be, /sup 9/Li, and /sup 7/He. However, no evidence was seen for any narrow levels in the T/sub z/ = /sup 3///sub 2/ nuclide /sup 5/H nor for any narrow excited states in /sup 7/He. The angular distributions reported here are rather featureless and decrease monotonically with increasing angle. This behavior can be shown by a semi-classical reaction theory to be a consequence of the reaction kinematics. A semi-classical approach also suggests that the kinematic term in the transition matrix element is only weakly dependent upon the angular momentum transfer (which is consistent with simple Distorted Wave Born Approximation calculations). However, only qualitative agreement was obtained between the observed relative transition yields and semi-classical predictions, using the two-nucleon coefficients of fractional parentage of Cohen and Kurath, probably due to the limitations of the semi-classical reaction theory.

Molecular epidemiology of Acinetobacter baumannii and Acinetobacter nosocomialis in Germany over a 5-year period (2005-2009).

Science.gov (United States)

Schleicher, X; Higgins, P G; Wisplinghoff, H; Körber-Irrgang, B; Kresken, M; Seifert, H

2013-08-01

To investigate the species distribution within the Acinetobacter calcoaceticus-Acinetobacter baumannii complex and the molecular epidemiology of A. baumannii and Acinetobacter nosocomialis, 376 Acinetobacter isolates were collected prospectively from hospitalized patients at 15 medical centres in Germany during three surveillance studies conducted over a 5-year period. Species identification was performed by molecular methods. Imipenem minimum inhibitory concentrations (MIC) were determined by broth microdilution. The prevalence of the most common carbapenemase-encoding genes was investigated by oxacillinase (OXA) -multiplex polymerase chain reaction (PCR). The molecular epidemiology was investigated by repetitive sequence-based PCR (rep-PCR; DiversiLab™). Acinetobacter pittii was the most prevalent Acinetobacter species (n = 193), followed by A. baumannii (n = 140), A. calcoaceticus (n = 10) and A. nosocomialis (n = 8). The majority of A. baumannii was represented by sporadic isolates (n = 70, 50%) that showed unique rep-PCR patterns, 25 isolates (18%) clustered with one or two other isolates, and only 45 isolates (32%) belonged to one of the previously described international clonal lineages. The most prevalent clonal lineage was international clone (IC) 2 (n = 34) and IC 1 (n = 6). According to CLSI, 25 A. baumannii isolates were non-susceptible to imipenem (MIC ≥ 8 mg/L), all of which produced an OXA-58-like or OXA-23-like carbapenemase. The rate of imipenem susceptibility among A. baumannii isolates decreased from 96% in 2005 to 76% in 2009. All other Acinetobacter isolates were susceptible to imipenem. The population structure of carbapenem-susceptible A. baumannii in Germany is highly diverse. Imipenem non-susceptibility was strongly associated with the clonal lineages IC 2 and IC 1. These data underscore the high clonality of carbapenem-resistant A. baumannii isolates. © 2012 The Authors. Clinical Microbiology and Infection © 2012 European Society of

Child maltreatment in Germany: prevalence rates in the general population.

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Witt, Andreas; Brown, Rebecca C; Plener, Paul L; Brähler, Elmar; Fegert, Jörg M

2017-01-01

Child maltreatment and its consequences are considered a major public health problem. So far, there is only one study from Germany reporting prevalence rates on different types of maltreatment. A representative sample of the German general population was examined for experiences of child maltreatment using the Childhood Trauma Questionnaire (CTQ) between September and November 2016. A total of 2510 (53.3% female) participants between 14 and 94 years (M = 48.8 years) were enrolled. Besides the CTQ, a range of sociodemographic information was collected. The interrelatedness of different types of maltreatment was examined using configuration analysis and predictors for maltreatment were identified by performing binary logistic regression analyses. Overall, 2.6% (f: 3.9%, m: 1.2%) of all participants reported severe emotional abuse, 3.3% (f: 3.4%, m: 3.3%) severe physical abuse, 2.3% (f: 3.7%, m: 0.7%) severe sexual abuse, 7.1% (f: 8.1%, m: 5.9%) severe emotional neglect and 9% (f: 9.2%, m: 8.9%) severe physical neglect. Women were more likely to report at least moderate sexual and emotional abuse than men. The largest difference between age groups was reported for physical neglect, with participants aged over 70 years reporting the highest rates. Participants who reported childhood maltreatment were more likely to be unemployed or have lower educational outcomes. The most common combination of maltreatment types were physical and emotional neglect, all five types of maltreatment combined and physical and emotional neglect and physical abuse combined. Child maltreatment, especially physical neglect is common in the German population. Women seem to be at greater risk for sexual and emotional abuse than men. Knowledge about different types of maltreatment based on the Childhood Trauma Questionnaire (CTQ) can help to put findings of future studies into an epidemiological and societal context.

6. Seminar of the IIE-ININ-IMP on technological specialties. Topic 8: computation

International Nuclear Information System (INIS)

1992-01-01

The document includes 10 papers presented at the 6. Seminar of the IIE-ININ-IMP (Mexico) on technological specialties in the field of computation. (Topic 8). Three items were in INIS subject scope and a separate abstract was prepared for each of them

Contribution of overweight and obesity to adverse pregnancy outcomes among immigrant and non-immigrant women in Berlin, Germany.

Science.gov (United States)

Reiss, Katharina; Breckenkamp, Jürgen; Borde, Theda; Brenne, Silke; David, Matthias; Razum, Oliver

2015-10-01

Maternal excessive weight and smoking are associated with an increased risk of pregnancy complications and adverse pregnancy outcomes. In Germany, immigrant women have a higher prevalence of pre-pregnancy overweight/obesity compared with autochthonous women. We compared the contribution of pre-pregnancy overweight/obesity to adverse pregnancy outcomes among immigrant and autochthonous women in Berlin/Germany. Data from 2586 immigrant women (from Turkey, Lebanon, other countries of origin) and 2676 autochthonous women delivering in three maternity hospitals of Berlin within 12 months (2011/2012) was used. Cox regression models were applied to estimate the association between overweight/obesity and smoking with the outcomes large-for-gestational-age (LGA), small-for-gestational-age (SGA), preterm birth (PTB) and extreme preterm-birth (E-PTB). Population attributive fractions (PAF) were calculated to quantify the proportion of the outcomes attributable to overweight/obesity and smoking, respectively. Prevalence of overweight and obesity was 33.4% among autochthonous and 53.6% among Turkish women. Prevalence risk ratios of excessive weight were highest for LGA infants among immigrant and autochthonous women. The PAFs were -11.8% (SGA), +16.3% (LGA), +3.6% (PTB) and +16.5% (E-PTB) for the total study population. Overweight/obesity is strongly associated with an increased risk of delivering an LGA infant among both immigrant and autochthonous women. Compared with autochthonous women, the contribution of excessive weight to LGA is even higher among immigrant women, in whom PAFs of overweight/obesity even exceed those of smoking for some outcomes. © The Author 2015. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

Report on the joint USA-Germany drop test program for a vitrified high level waste cask

International Nuclear Information System (INIS)

Golliher, K.G.; Witt, C.R.; Wieser, K.E.

1993-01-01

A series of full-scale drop tests was performed on a ductile iron transport cask in a cooperative program between the US Department of Energy (DOE) and Bundesantalt fuer Materialpruefung (BAM) in Germany. The tests, which were performed at BAM's test facility located near Lehre, Germany, were performed on a prototype cask designed for transport of Vitrified High Level Waste (VHLW) canisters. The VHLW cask is a right circular cylinder with a diameter of 1156 mm and a height of 3454 cm, and weighs approximately 24.6 kg including its payload of a single VHLW canister. The drop tests were performed with a non-radioactive, prototype VHLW canister in the cavity. (J.P.N.)

The costs of coexistence on farms in Germany

DEFF Research Database (Denmark)

Punt, Maarten J.; Venus, Thomas J.; Wesseler, Justus H H

2017-01-01

for farmers in their cultivation decisions, and therefore it is important to measure these costs. In this article, we investigate the costs of different coexistence measures for farmers in Germany. Currently, GM crop cultivation is outlawed in Germany, but there was a short period from 2005-2008 when...... that there are important differences in farm characteristics and overall landscape configuration that influence the costs or burden of coexistence measures....

Prevalence and Genotype Allocation of Pathogenic Leptospira Species in Small Mammals from Various Habitat Types in Germany.

Science.gov (United States)

Obiegala, Anna; Woll, Dietlinde; Karnath, Carolin; Silaghi, Cornelia; Schex, Susanne; Eßbauer, Sandra; Pfeffer, Martin

2016-03-01

Small mammals serve as most important reservoirs for Leptospira spp., the causative agents of Leptospirosis, which is one of the most neglected and widespread zoonotic diseases worldwide. The knowledge about Leptospira spp. occurring in small mammals from Germany is scarce. Thus, this study's objectives were to investigate the occurrence of Leptospira spp. and the inherent sequence types in small mammals from three different study sites: a forest in southern Germany (site B1); a National Park in south-eastern Germany (site B2) and a renaturalised area, in eastern Germany (site S) where small mammals were captured. DNA was extracted from kidneys of small mammals and tested for Leptospira spp. by real-time PCR. Positive samples were further analysed by duplex and conventional PCRs. For 14 positive samples, multi locus sequence typing (MLST) was performed. Altogether, 1213 small mammals were captured: 216 at site B1, 456 at site B2 and 541 at site S belonging to following species: Sorex (S.) araneus, S. coronatus, Apodemus (A.) flavicollis, Myodes glareolus, Microtus (Mi.) arvalis, Crocidura russula, Arvicola terrestris, A. agrarius, Mustela nivalis, Talpa europaea, and Mi. agrestis. DNA of Leptospira spp. was detected in 6% of all small mammals. At site B1, 25 small mammals (11.6%), at site B2, 15 small mammals (3.3%) and at site S, 33 small mammals (6.1%) were positive for Leptospira spp. Overall, 54 of the positive samples were further determined as L. kirschneri, nine as L. interrogans and four as L. borgpetersenii while five real-time PCR-positive samples could not be further determined by conventional PCR. MLST results revealed focal occurrence of L. interrogans and L. kirschneri sequence type (ST) 117 while L. kirschneri ST 110 was present in small mammals at all three sites. Further, this study provides evidence for a particular host association of L. borgpetersenii to mice of the genus Apodemus.

Germany's Armed Forces in the Second World War: Manpower, Armaments, and Supply.

Science.gov (United States)

Balsamo, Larry T.

1991-01-01

Discusses the state of Germany's armed forces in World War II. Describes Germany's progress from inferior weaponry and unprepared military at the beginning of the war to superior weapons and fighting. Stresses heavy German dependence on horse drawn supply. Credits Germany's defeat to human attrition accelerated by Hitler's operational leadership.…

The essence of alternative medicine. A dermatologist's view from Germany.

Science.gov (United States)

Happle, R

1998-11-01

In Germany, alternative medicine is presently very popular and is supported by the federal government. When deliberating on the essence of alternative medicine we should simultaneously reflect on the intellectual and moral basis of regular medicine. To provide an epistemological demarcation of the 2 fields, the following 12 theses are advanced: (1) alternative and regular medicine are speaking different languages; (2) alternative medicine is not unconventional medicine; (3) the paradigm of regular medicine is rational thinking; (4) the paradigm of alternative medicine is irrational thinking; (5) the present popularity of alternative medicine can be explained by romanticism; (6) some concepts of alternative medicine are falsifiable and others are not; (7) alternative medicine and evidence-based medicine are mutually exclusive; (8) the placebo effect is an important factor in regular medicine and the exclusive therapeutic principle of alternative medicine; (9) regular and alternative medicine have different aims: coming of age vs faithfulness; (10) alternative medicine is not always safe; (11) alternative medicine is not economic; and (12) alternative medicine will always exist. The fact that alternative methods are presently an integral part of medicine as taught at German universities, as well as of the physician's fee schedule, represents a collective aberration of mind that hopefully will last for only a short time.

Football business models: Why did Germany win the World Cup?

DEFF Research Database (Denmark)

Cortsen, Kenneth

2016-01-01

This article looks into the managerial aspects related to why and how Germany won the 2014 FIFA World Cup.......This article looks into the managerial aspects related to why and how Germany won the 2014 FIFA World Cup....

Erosion of the 4-6- and 8 group transition metals under intense laser radiation

International Nuclear Information System (INIS)

Samsonov, G.V.; Verkhoturov, A.D.; Roshchina, A.I.; Vasil'ev, A.V.; Klimenko, V.P.

1976-01-01

The erosion resistance is studied of transition metals of Groups 4-6 and 8 at laser emission of approximately 6x1O 7 W/cm 2 . It is shown that as the emission power increases from 10 6 to 6x10 7 W/cm 2 the erosion values show an increase over tenfold without any subsequent filling of the craters. The growth of the metallic erosion is largely caused by a greater crater diameter. The erosion resistance of metals enhances in the following series: Ti-Zr-Co-Ni-Fe, Hf-V-Nb-Mo-Cr-Ta-W-Cu

[Pharmacological aspects of pain research in Germany].

Science.gov (United States)

Niederberger, E; Kuner, R; Geißlinger, G

2015-10-01

In spite of several approved analgesics, the therapy of pain still constitutes a challenge due to the fact that the drugs do not exert sufficient efficacy or are associated with severe side effects. Therefore, the development of new and improved painkillers is still of great importance. A number of highly qualified scientists in Germany are investigating signal transduction pathways in pain, effectivity of new drugs and the so far incompletely investigated mechanisms of well-known analgesics in preclinical and clinical studies. The highlights of pharmacological pain research in Germany are summarized in this article.

Two versions of solomon's prayer (1 kings 8 and 2 chronicles 6): a ...

African Journals Online (AJOL)

. We find this prayer in two different theological and literary traditions of the Bible: 1 Kings 8:22-53 and 2 Chronicles 6:12-42. In the light of these parallel versions one may pose the following questions: What are the similarities and differences ...

The expansion of electricity generation from renewable energies in Germany

International Nuclear Information System (INIS)

Buesgen, Uwe; Duerrschmidt, Wolfhart

2009-01-01

The expansion of electricity generation from renewable sources in Germany is promoted by the Erneuerbare-Energien-Gesetz (EEG), which was last amended in June 2008. In a review of the EEG the political parameters, the progress achieved, and the impacts of the Act itself are set out. This Progress Report addresses cross-sectoral aspects, notably CO 2 emissions reduction, job creation, investment and turnover in the renewables industry, and that industry's prospects for the future. Trends in the individual renewables sectors are described and policy recommendations formulated, as appropriate, on this basis. The policy recommendations have been incorporated into the new EEG from 6 June 2008. The overarching goal of the new EEG is to achieve a renewables share of at least 30% in Germany's electricity consumption in 2020. This underlines the need for radical modernisation of the energy system as a whole. This article presents an overview of the content of the Progress Report and supplements it with current statistical data and research findings contained in other publications from the Federal Ministry for the Environment (BMU). It also highlights the points on which the new EEG diverges from the policy recommendations contained in the Progress Report.

Acidification policy - control of acidifying emissions in Germany

International Nuclear Information System (INIS)

Schaerer, B.

1992-01-01

Since the mid-eighties total annual acidifying emissions have started to decline in West Germany. There was considerable impact on this positive trend in air pollution by the control of SO 2 and NO x emissions from large boilers, which were reduced by more than 80%. Corresponding control programmes have been established for other groups of sources as well as other pollutants and - with unification - for East Germany. The driving force behind this development was and still is first of all the legal principle of anticipatory action or precaution which means in practical terms 'emission minimization'. This cornerstone of German clean air legislation is the most powerful components of Germany's 'acidification policy', as it requires policy-makers to draw up new or review existing regulations for emission reduction based on requirements according to the state of the art and forces operators to apply the most modern ways and means of operation. This paper describes the system used in Germany to deal with air pollution, the emission minimization strategy, and the actions against acidifying emissions based thereon. In addition, an outlook on what might be necessary to cope with the challenges of a sustainable development concerning acidification is given. 1 ref., 1 fig., 2 tabs

Working conditions and effort-reward imbalance of German physicians in Sweden respective Germany: a comparative study.

Science.gov (United States)

Ohlander, Johan; Weigl, Matthias; Petru, Raluca; Angerer, Peter; Radon, Katja

2015-05-01

Work stress among physicians is a growing concern in various countries and has led to migration. We compared the working conditions and the work stress between a migrated population of German physicians in Sweden and a population of physicians based in Germany. Additionally, specific risk factors for work stress were examined country wise. Using a cross-sectional design, 85 German physicians employed in Sweden were surveyed on working conditions and effort-reward imbalance and compared with corresponding data on 561 physicians working in Germany. Multiple linear regression analyses were applied on both populations separately to model the associations between working conditions and effort-reward ratio (ERR), adjusted for a priori confounders. German physicians in Sweden had a significantly lower ERR than physicians in Germany: mean (M) = 0.47, standard deviation (SD) = 0.24 vs. M = 0.80, SD = 0.35. Physicians in Sweden worked on average 8 h less per week and reported higher work support and responsibility. Multivariate analyses showed in both populations a negative association between work support and the ERR (β = -0.148, 95% CI -0.215 to (-0.081) for physicians in Sweden and β = -0.174, 95% CI -0.240 to (-0.106) for physicians in Germany). Further significant associations with the ERR were found among physicians in Sweden for daily breaks (β = -0.002, 95% CI -0.004 to (-0.001)) and among physicians in Germany for working hours per week (β = 0.006, 95% CI 0.002-0.009). Our findings show substantial differences in work stress and working conditions in favor of migrated German physicians in Sweden. To confirm our results and to explain demonstrated differences in physicians' work stress, longitudinal studies are recommended.

Climatic change in Germany. Development, consequences, risks and perspectives

International Nuclear Information System (INIS)

Brasseur, Guy; Jacob, Daniela; Schuck-Zoeller, Susanne

2017-01-01

The book on the climatic change in Germany includes contributions to the following issues: global climate projections and regional projections in Germany and Europe: observation of the climatic change in Central Europe, regional climate modeling, limits and challenges of the regional climate modeling; climatic change in Germany - regional features and extremes: temperature and heat waves, precipitation, wind and cyclones, sea-level increase, tides, storm floods and sea state, floods, definition uncertainties, draughts, forest fires, natural risks; consequences of the climatic change in Germany: air quality, health, biodiversity, water resources, biochemical cycles, agriculture, forestry, soils, personal and commercial transport, cities and urban regions, tourism, infrastructure, energy and water supplies, cost of the climatic change and economic consequences; overall risks and uncertainties: assessment of vulnerabilities, literature review, climatic change as risk enhancement in complex systems, overall risks and uncertainties, decision making under uncertainties in complex systems; integrated strategies for the adaptation to the climatic change: the climate resilient society - transformations and system changes, adaptation to the climatic change as new political field, options for adaptation strategies.

The photovoltaic sector in Germany, where does it go?

International Nuclear Information System (INIS)

Anon.

2012-01-01

Opinion polls show that photovoltaic power is very popular in Germany. This sector employs about 130.000 people and although a lot of solar modules are imported from China, other components like current inverters are fabricated in Germany and as a whole the trade balance is positive and the export rate nears 50%. In 2011 Germany invested 25 billion euros in the photovoltaic sector and now about 5% of the consumed electricity is photovoltaic power. Photovoltaic power reached grid parity in february 2012 for some consumers and the German government decided to reduce the purchase tariff drastically which may jeopardize the aim of having a photovoltaic park of 51 GWc by 2020. (A.C.)

The new 6 MW gas turbine for the power generation; Die neue 6 MW Gasturbine fuer die Stromerzeugung

Energy Technology Data Exchange (ETDEWEB)

Blaswich, Michael; Theis, Sascha [MAN Diesel and Turbo SE, Oberhausen (Germany)

2012-07-01

MAN Diesel and Turbo SE (Oberhausen, Federal Republic of Germany) had developed a new gas turbine in the 6 MW class. This device is the founding stone for a family of gas turbines which at first cover the power range from 6 to 8 MW for the propulsion of pumps, compressors and electric devices. The two-shaft industrial gas turbine consists of a gas generator with an axial compressor with eleven levels, six external single combustion chambers, one two-step high-pressure turbine and a two-step power turbine. Beside the two-shaft industrial gas turbine, there exists a single-shaft industrial gas turbine for the power generation. The single-shaft industrial gas turbine consists of three turbine stages, a gas turbine compressor and combustion chamber being identical in construction to the two-shaft industrial gas turbine. The gas turbine package contains the gas turbine module as well as a filter module. The gas turbine was successfully tested. Further tests and the commissioning of the first customer's plant are planned for this year.

Extension for Organic Agriculture: A Comparative Study between Baden-Württemberg, Germany and Crete, Greece

Science.gov (United States)

Österle, Nina; Koutsouris, Alex; Livieratos, Yannis; Kabourakis, Emmanuil

2016-01-01

Purpose: The aim of this paper is to compare the extension services offered in the field of organic agriculture (OA) in Baden-Württemberg (BW), Germany and Crete, Greece. Design/methodology approach: 16 in-depth interviews, 10 in BW and 6 in Crete, were carried out with representatives of OA extension providers; interviews were qualitatively…

Molybdenum Cluster Chalcogenides: In Situ X-Ray Studies on the Formation of Cu xMo 6S 8 via Electron/Ion Transfer

Science.gov (United States)

Fischer, C.; Gocke, E.; Stege, U.; Schöllhorn, R.

1993-01-01

Systematic structural investigation have been performed on the formation of the ternary Chevrel phase system CuxMo6S8 by topotactic intercalation of copper into Mo6S8 via electron/ion transfer reactions. In high-temperature synthesis the homogeneity range of CuxMo6S8 formation corresponds to 1.8 ≤ x ≤ 3.66, while by galvanostatic or potentiostatic reduction of binary Mo6S8 at ambiet temperature in aqueous CuSO4 or aprotic CuCl/Ch3CN electrolyte the terminal rhombohedral phase Cu4Mo6S8 with the maximum number of electrons per Mo6 cluster can be obtained. The phase range 1 ≤ x ≤ 4 of CuxMo6S8 as obtained by galvanostatic reduction of Mo6S8 in aqueous CuSO4 electrolyte has been determined by in situ X-ray experiments. Warburg oxygen manometry has proved to be a new and powerful analytical tool for examination of the Cu content of ternary phase CuxMo6S8. Thermodiffractometry and 63 Cu NMR studies of Cu2Mo6S8 (high-temperature phase) reveal a phase-transition rhombohedral/triclinic in a broad temperature range between 285 and 200 K. Superconducting properties (temperature-dependent ac susceptibility) of high temperature and electrochemically prepared Cu phases are reported.

Treatment of intractable epilepsy in a female with SLC6A8 deficiency

NARCIS (Netherlands)

Mercimek-Mahmutoglu, S.; Connolly, M.B.; Poskitt, K.J.; Horvath, G.A.; Lowry, N.; Salomons, G.S.; Casey, B.; Sinclair, G.; Davis, C.; Jakobs, C.; Stockler-Ipsiroglu, S.

2010-01-01

A female heterozygous for a novel, disease causing, missense mutation in the X-linked cerebral creatine transporter (SLC6A8) gene (c.1067G > T, p.Gly356Val) presented with intractable epilepsy, mild intellectual disability and moderately reduced cerebral creatine levels. Treatment with creatine

Synthesis of high-purity Li{sub 8}ZrO{sub 6} powder by solid state reaction under hydrogen atmosphere

Energy Technology Data Exchange (ETDEWEB)

Shin-mura, Kiyoto; Otani, Yu; Ogawa, Seiya [Course of Mechanical Engineering, Graduate School of Engineering, Tokai University, 4-1-1 Kitakaname, Hiratsuka, Kanagawa 259-1292 (Japan); Niwa, Eiki; Hashimoto, Takuya [Department of Physics, College of Humanities and Sciences, Nihon University, 3-8-1 Sakurajousui, Setagaya-ku, Tokyo 156-8550 (Japan); Hoshino, Tsuyoshi [Breeding Functional Materials Development Group, Department of Blanket Systems Research, Rokkasho Fusion Institute, Sector of Fusion Research and Development, Japan Atomic Energy Agency, 2-166 Obuchi, Omotedate, Rokkasho-mura, Kamikita-gun, Aomori 039-3212 (Japan); Sasaki, Kazuya, E-mail: k_sasaki@tokai-u.ac.jp [Course of Mechanical Engineering, Graduate School of Engineering, Tokai University, 4-1-1 Kitakaname, Hiratsuka, Kanagawa 259-1292 (Japan); Department of Prime Mover Engineering, School of Engineering, Tokai University, 4-1-1 Kitakaname, Hiratsuka, Kanagawa 259-1292 (Japan)

2016-11-01

Highlights: • A fine pure Li{sub 8}ZrO{sub 6} powder was synthesized by using Li{sub 2}CO{sub 3} and ZrO{sub 2} via a solid state reaction. • Influences on the purity of product powder, lattice defect, and crystal orientation were revealed. • The suitable synthesis conditions of the fine and high purity Li{sub 8}ZrO{sub 6} powder were found. • The reaction process of the synthesis of Li{sub 8}ZrO{sub 6} was estimated. - Abstract: Li{sub 8}ZrO{sub 6} contains a large amount of Li and has a significant potential as a tritium breeder. However, few syntheses of fine-grain, high-purity Li{sub 8}ZrO{sub 6} powder have been reported. In this study, a high-purity powder of Li{sub 8}ZrO{sub 6} was synthesized by solid state reaction under hydrogen atmosphere combined with an effective lithium source and a suitable initial Li:Zr molar ratio. Mixed powders of Li{sub 2}CO{sub 3} and ZrO{sub 2} were fired at around 630 °C in H{sub 2} for several hours and several firing cycles. The low firing temperature inhibited the vaporization of Li during the heating, so that excessive amounts of Li were not needed for the synthesis, and the Li:Zr ratio in the starting material was 10:1 (mol:mol). In this synthesis, Li{sub 2}O was generated via the decomposition of Li{sub 2}CO{sub 3} during firing in H{sub 2}, and reacted with ZrO{sub 2} to form Li{sub 6}Zr{sub 2}O{sub 7}, which reacted with itself to form Li{sub 8}ZrO{sub 6}.

Bromine-rich Zinc Bromides: Zn6Br12(18-crown-6)2×(Br2)5, Zn4Br8(18-crown-6)2×(Br2)3, and Zn6Br12(18-crown-6)2×(Br2)2.

Science.gov (United States)

Hausmann, David; Feldmann, Claus

2016-06-20

The bromine-rich zinc bromides Zn6Br12(18-crown-6)2×(Br2)5 (1), Zn4Br8(18-crown-6)2×(Br2)3 (2), and Zn6Br12(18-crown-6)2×(Br2)2 (3) are prepared by reaction of ZnBr2, 18-crown-6, and elemental bromine in the ionic liquid [MeBu3N][N(Tf)2] (N(Tf)2 = bis(trifluoromethylsulfonyl)amide). Zn6Br12(18-crown-6)2×(Br2)5 (1) is formed instantaneously by the reaction. Even at room temperature, compound 1 releases bromine, which was confirmed by thermogravimetry (TG) and mass spectrometry (MS). The release of Br2 can also be directly followed by the color and density of the title compounds. With controlled conditions (2 weeks, 25 °C, absence of excess Br2) Zn6Br12(18-crown-6)2×(Br2)5 (1) slowly releases bromine with conconcurrent generation of Zn4Br8(18-crown-6)2×(Br2)3 (2) (in ionic liquid) and Zn6Br12(18-crown-6)2×(Br2)2 (3) (in inert oil). All bromine-rich zinc bromides contain voluminous uncharged (e.g., Zn3Br6(18-crown-6), Zn2Br4(18-crown-6)) or ionic (e.g., [Zn2Br3(18-crown-6)](+), [(Zn2Br6)×(Br2)2](2-)) building units with dibromine molecules between the Zn oligomers and partially interconnecting the Zn-containing building units. Due to the structural similarity, the bromine release is possible via crystal-to-crystal transformation with retention of the crystal shape.

Reversible and irreversible magnetization of the Chevrel-phase superconductor PbMo6S8

International Nuclear Information System (INIS)

Zheng, D.N.; Ramsbottom, H.D.; Hampshire, D.P.

1995-01-01

Magnetic measurements have been carried out on the hot-isostatically-pressed Chevrel-phase superconductor PbMo 6 S 8 at temperatures from 4.2 K to T c and for magnetic fields up to 12 T. The results show that for the PbMo 6 S 8 compound there is a wide magnetically reversible region, between the irreversibility field B irr and the upper critical field B c2 , on the isothermal magnetic hysteresis curves. The B irr (T) line, i.e., the irreversibility line, was found to obey a power-law expression: B irr =B * (1-T/T c ) α with α∼1.5. Magnetic relaxation measurements revealed that the flux-creep effect in the material studied is substantial and is greater than those observed in conventional metallic alloys, but smaller than in high-temperature superconductors. The existence of the irreversibility line and pronounced flux-creep effect in PbMo 6 S 8 is attributed to the short coherence length of the material. From the reversible magnetization data, the values of the penetration depth, the coherence length, and the critical fields are obtained together with the Ginzburg-Landau parameter κ. At 4.2 K, the critical current density J c is 10 9 A m -2 at zero field, and decreases to 2x10 8 A m -2 at 10 T. Pinning force curves measured at different temperatures obey a Kramer-scaling law of the form: F p (=J c xB)∝b 1/2 (1-b) 2 , which indicates that the J c is limited by one predominant flux-pinning mechanism

Adverse events following immunisation with a meningococcal serogroup B vaccine: report from post-marketing surveillance, Germany, 2013 to 2016.

Science.gov (United States)

Mentzer, Dirk; Oberle, Doris; Keller-Stanislawski, Brigitte

2018-04-01

Background and aimIn January 2013, a novel vaccine against Neisseria meningitidis serogroup B, the multicomponent meningococcal serogroup B vaccine (4CMenB), was approved by the European Medicines Agency. We aimed to evaluate the safety profile of this vaccine. Methods: All adverse events following immunisation (AEFI) reported from Germany since the vaccine's launch in Germany in November 2013 through December 2016 were reviewed and analysed. Results: Through December 2016, a total of 664 individual case safety reports (ICSR) notifying 1,960 AEFI were received. A majority of vaccinees for whom AEFI were reported were children 2 to 11 years of age (n = 280; 42.2%) followed by infants and toddlers aged 28 days to 23 months (n = 170; 25.6%). General disorders and administration site conditions was the System Organ Class (SOC) with the majority of AEFI (n = 977; 49.8%), followed by nervous system disorders (n = 249; 12.7%), and skin and subcutaneous tissue disorders (n = 191; 9.7%). Screening of patient records for immune-mediated and neurological diseases did not raise any safety signal in terms of an increased proportional reporting ratio (PRR). Conclusions: The safety profile described in the Summary of Product Characteristics, in general, is confirmed by data from spontaneous reporting. No safety concerns were identified.

Radioactive waste management in West Germany

Energy Technology Data Exchange (ETDEWEB)

Krause, H [Kernforschungszentrum Karlsruhe G.m.b.H. (Germany, F.R.)

1978-01-01

The technologies developed in West Germany for radioactive waste management are widely reviewed. The first topic in this review paper is the disposal of low- and middle-level radioactive liquid wastes. Almost all these liquid wastes are evaporated, and the typical decontamination factor attained is 10/sup 4/ -- 10/sup 6/. The second topic is the solidification of residuals. Short explanation is given to bituminization and some new processes. The third topic is high-level liquid wastes. Degradation of glass quality due to various radiation is discussed. Embedding of small glass particles containing radioactive wastes into metal is also explained. Disposals of low-level solid wastes and the special wastes produced from reprocessing and mixed oxide fuel fabrication are explained. Final disposal of radioactive wastes in halite is discussed as the last topic. Many photographs are used to illustrate the industrial or experimental use of those management methods.

GEP 6.5LT Engine Cetane Window Evaluation for ATJ/JP-8 Fuel Blends

Science.gov (United States)

2015-09-01

matching pre- calibrated amplifier • BEI Shaft Encoder (0.2 CAD) • Wolff Instrumented Injector for needle lift The high speed data was recorded and post...14. ABSTRACT The European Stationary Cycle 13 Mode test and a power curve was performed on a 6.5L turbocharged V-8 diesel engine for three ATJ...15. SUBJECT TERMS ATJ, Alcohol to Jet, Cetane Number, Synthetic Fuel, JP-8, diesel engine, combustion 16. SECURITY CLASSIFICATION OF: 17

Antidiarrheal Thymol Derivatives from Ageratina glabrata. Structure and Absolute Configuration of 10-Benzoyloxy-8,9-epoxy-6-hydroxythymol Isobutyrate

Directory of Open Access Journals (Sweden)

Celia Bustos-Brito

2016-09-01

Full Text Available Chemical investigation of the leaves from Ageratina glabrata yielded four new thymol derivatives, namely: 10-benzoyloxy-8,9-dehydro-6-hydroxythymol isobutyrate (4, 10-benzoyloxy-8,9-dehydrothymol (5, 10-benzoyloxythymol (6 and 10-benzoyloxy-6,8-dihydroxy-9-isobutyryl-oxythymol (7. In addition, (8S-10-benzoyloxy-8,9-epoxy-6-hydroxythymol isobutyrate (1, together with other two already known thymol derivatives identified as 10-benzoyloxy-8,9-epoxy-6-methoxythymol isobutyrate (2 and 10-benzoyloxy-8,9-epoxythymol isobutyrate (3 were also obtained. In this paper, we report the structures and complete assignments of the 1H and 13C-NMR data of compounds 1–7, and the absolute configuration for compound 1, unambiguously established by single crystal X-ray diffraction, and evaluation of the Flack parameter. The in vitro antiprotozoal assay showed that compound 1 and its derivative 1a were the most potent antiamoebic and antigiardial compounds. Both compounds showed selectivity and good antiamoebic activity comparable to emetine and metronidazole, respectively, two antiprotozoal drugs used as positive controls. In relation to anti-propulsive effect, compound 1 and 1a showed inhibitory activity, with activities comparable to quercetin and compound 9, two natural antipropulsive compounds used as positive controls. These data suggest that compound 1 may play an important role in antidiarrheal properties of Ageratina glabrata.

Prioritizing the patient: optimizing therapy in rheumatoid arthritis. Results of a patient questionnaire in northern Germany

Directory of Open Access Journals (Sweden)

Wollenhaupt J

2013-05-01

Full Text Available Jürgen Wollenhaupt,1 Inge Ehlebracht-Koenig,2 André Groenewegen,3 Dieter Fricke41Rheumatologikum Hamburg, Schön Klinik Hamburg Eilbek, Hamburg, Germany; 2Center of Rehabilitation, Bad Eilsen, Germany; 3UCB Pharma SA, Brussels, Belgium; 4UCB Pharma GmbH, Monheim, GermanyPurpose: A 40-question postal survey was developed to gain insight into the nature of difficulties experienced by patients due to rheumatoid arthritis (RA, as well as patient perceptions and priorities regarding their RA treatmentPatients and methods: A total of 3000 Lower Saxony, Germany members of Rheuma-Liga (RL, a patient support group for people with RA, were invited to participate between July 1, and August 20, 2009. The questionnaire was divided into four sections: (1 patient demographics, (2 quality of life (QOL, (3 treatment expectations and, (4 patient perceptions of RL. The questionnaire could be completed in writing or via the internet.Results: Of 959 respondents (response rate = 32.0%, 318 had diagnosed RA and were included in the analysis. The respondents were mostly retired (71.2%, female (83.3%, and >60 years of age (63.5%. Members’ responses indicated that most were generally satisfied with their current treatment (67.3%, considered it efficacious (84.0%, and reported minimal (none or little side-effects (61.2%. Patient involvement in treatment decisions, however, was reportedly low (49.6% felt insufficiently involved. Patients’ primary impairments were reflected in their treatment priorities: mobility (97.0%, ability to run errands/do shopping (97.1%, do the housework (95.6%, and be independent of others (94.2%. The primary service provided by RL and used by respondents was physiotherapy (70.6%, which was reported to benefit physical function and mood by over 90.0% of respondents.Conclusion: RA had a detrimental effect upon respondents' quality of life, specifically impairing their ability to perform daily tasks and causing pain/emotional distress

Molecular structure and vibrational spectra of 6-methylquinoline and 8-methylquinoline molecules by quantum mechanical methods

International Nuclear Information System (INIS)

Kurt, M.

2005-01-01

The molecular geometry and vibrational frequencies of 6-methylquinoline(6MQ) and 8-methylquinolines(8MQ) in the ground state have been calculated by using the Hartree-Fock and density functional methods (B3LYP and BLYP) with 6-31G (d) as the basis set. The optimized geometric bond lengths obtained by using B3LYP and bond angles obtained by BLYP were given corresponding experimental values of similar molecule. Comparison of the observed fundamental vibrational frequencies of these molecules and calculated results by density functional B3LYP, BLYP and Hartree-Fock methods indicates that B3LYP is superior to the scaled Hartree- Fock and BLYP approach for molecular vibrational problems

Regional cost differences of hospital supply in Germany

Directory of Open Access Journals (Sweden)

Lauterbach, Karl W.

2005-04-01

Full Text Available The intended adoption of a global reimbursement system for inpatient care in Germany envisions identical payments for identical treatments at different hospitals. This may lead to losses in some hospitals and may cause problems for the supply with health care facilities in the long run if there a important regional cost differences. Cost and performance data of 1112 hospitals in Germany have been analysed for regional differences in 2001: As regional categorizations we used official classification schemes based on centrality. The investigation does not support the postulation of additional payments for selected regions in Germany accounting for level cost-differences between hospitals. Confounding influence factors like ownership and hospital size seem to be more important. We recommend further investigations to evaluate regional cost-differences on the level of medical wards and using more risk-adjusted data. The examination of the individual case is necessary.

Laboratory Synthesized Calcium Oxide and Calcium Hydroxide Grains: A Candidate to Explain the 6.8 Micron Band

Science.gov (United States)

Kimura, Yuki; Nuth, Joseph A., III

2005-01-01

We will demonstrate that CaO and Ca(OH)2 are excellent candidates to explain the 6.8 microns feature, which is one of the most obscure features in young stellar objects. We discuss the condensation of CaO grains and the potential formation of a Ca(OH)2 surface layer. The infrared spectra of these grains are compared with the spectra of fifteen young stellar objects. We note that CaO-rich grains are seen in all meteoritic CAIs (calcium-aluminum-rich inclusions) and the 6.8 micron feature has only been observed in young stellar objects. Therefore, we consider CaO grains to be a plausible candidate to explain the 6.8 microns feature and hypothesize that they are produced in the hot interiors of young stellar environments.

A study on the redox, spectroscopic, and photophysical characteristics of a series of octahedral hexamolybdenum(ii) clusters: [{Mo6X8}Y6]2- (X, Y = Cl, Br, or I).

Science.gov (United States)

Akagi, Soichiro; Fujii, Sho; Kitamura, Noboru

2018-01-23

We report a systematic study on the redox, spectroscopic, and photophysical properties of a series of [{Mo 6 X 8 }Y 6 ] 2- (X, Y = Cl, Br, or I. 1-9). All of the [{Mo 6 X 8 }Y 6 ] 2- clusters show intense and long-lived phosphorescence in both CH 3 CN and crystalline phases at 298 K. We found that the emission quantum yields (Φ em ) of 1-9 increase in the sequences X = Cl Br Br Br < Cl for given {Mo 6 X 8 } 4+ -core clusters. The present data demonstrate that arbitrary combinations of X and Y in [{Mo 6 X 8 }Y 6 ] 2- could tune τ em and Φ em in the ranges of 85-300 μs and 0.09-0.47, respectively. Both capping (X) and terminal ligand (Y) effects on the photophysical properties of the clusters are discussed on the basis of the energy gap (i.e., emission energy) dependence of the nonradiative decay rate constant.

HTGR type reactors in West Germany. Realizations and prospects

International Nuclear Information System (INIS)

Dauenert, U.

1978-01-01

The framework within which the research studies on high temperature reactors have been pursued in West Germany since 1960 is recalled. The principles guiding the present policy of the country in this domain are given: choice of a single technical conception that be applied both to reactors generating electricity and reactors producing high temperature heat for industrial processes such as coal gasification; to group the technical and industrial potentials of West Germany in this domain; financial and technical participation of electricity producers in the expected realizations; international cooperation. In this technique, West Germany is at present among the most advanced nations with the realization of a prototype 300 MWe reactor, financed by the electricity producers and a contribution of government [fr

Radioactive waste in Federal Germany

International Nuclear Information System (INIS)

Brennecke, P.; Schumacher, J.; Warnecke, E.

1988-01-01

The Physikalisch-Technische Bundesanstalt (PTB) is responsible for the long-term storage and disposal of radioactive waste according to the Federal Atomic Energy Act. On behalf of the Federal Minister of the Environment, Nature Conservation and Nuclear Safety, since 1985, the PTB has been carrying out annual inquiries into the amounts of radioactive waste produced in the Federal Republic of Germany. Within the scope of this inquiry performed for the preceding year, the amounts of unconditioned and conditioned waste are compiled on a producer- and plant-specific basis. On the basis of the inquiry for 1986 and of data presented to the PTB by the waste producers, future amounts of radioactive waste have been estimated up to the year 2000. The result of this forecast is presented. In the Federal Republic of Germany two sites are under consideration for disposal of radioactive waste. In the abandoned Konrad iron mine in Salzgitter-Bleckenstedt it is intended to dispose of such radioactive waste which has a negligible thermal influence upon the host rock. The Gorleben salt dome is being investigated for its suitability for the disposal of all kinds of solid and solidified radioactive wastes, especially of heat-generating waste. Comparing the estimated amount of radioactive wastes with the capacity of both repositories it may be concluded that the Konrad and Gorleben repositories will provide sufficient capacity to ensure the disposal of all kinds of radioactive waste on a long-term basis in the Federal Republic of Germany. 1 fig., 2 tabs

Outbreak of hepatitis A in two federal states of Germany: bakery products as vehicle of infection.

Science.gov (United States)

Schenkel, K; Bremer, V; Grabe, C; Van Treeck, U; Schreier, E; Höhne, M; Ammon, A; Alpers, K

2006-12-01

In April 2004, increased numbers of hepatitis A were noted in six neighbouring districts in Germany. Exploratory interviews showed that patients had consumed bakery products from company X where two employees had been diagnosed with hepatitis A in February. A case-control study of consumption of products of company X was carried out through telephone interviews. Altogether, 64 cases were identified. Fifty-two cases and 112 controls aged >or=16 years were included in the case-control study. In total, 46/52 cases and 37/112 controls had consumed company X products [odds ratio (OR) 15.5, 95% confidence interval (CI) 6.1-39.7]. Of these, 36/46 cases and 16/37 controls had consumed pastries (OR 4.7, 95% CI 1.8-12.3), 25/46 cases and 12/37 controls had consumed filled doughnuts (OR 2.5, 95% CI 1.0-6.1). Sequence analysis of the VP1-2A junction region indicated 100% strain homology between cases and an infected employee of company X. We recommended reinforcement of hygiene precautions, and consideration of a prolongation of compulsory work absence after post-exposure vaccination.

B8B8 interaction in the SU6 quark model and its applications to few-body systems

International Nuclear Information System (INIS)

Fujiwara, Y.; Miyagawa, K.; Kohno, M.; Suzuki, Y.; Nakamoto, C.

2004-01-01

The recent QCD-inspired spin-flavor SU 6 quark model for the baryon-baryon interaction, proposed by the Kyoto-Niigata group, is a unified model for the complete baryon octet (B 8 =N, Λ, Σ and Ξ), which has achieved very accurate description of the NN and YN interactions. These quark-model interactions are now applied to realistic calculations of few-body systems in a new three-cluster Faddeev formalism which uses the 2-cluster resonating-group method kernel explicitly. We review the essential features of the most recent models, fss2 and FSS, and their predictions to few-body systems in confrontation with the available experimental data. As the few-body systems, we discuss the three-nucleon bound states, 2αΛ system for Λ 9 Be, and 2Λα system for ΛΛ 6 He. (author)

Germany versus the United States: Monetary Dominance in the Eurozone

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Chee-Heong Quah

2016-04-01

Full Text Available This study inspects if there is greater convergence with Germany amongst the Eurozone founding members and if their relations with the hegemonic economy have been more symmetrical after “euroization”. The dimensions explored are those inspired by the optimum currency areas (OCA framework. To some extent, the findings could signify if real convergence has been significantly endogenous. At the same time, to assess the relative dominance of Germany, the features against Germany are compared to those against US. In addition, the paper also appraises some aspects of economic performance to check whether economic conditions across the states have improved and converged after unification. In some convergence aspects, findings suggest remarkable convergence with Germany and across the states but also relative convergence with US. On economic performance, results indicate substantial improvements in inflation and unemployment. Amongst the founding states, Ireland has idiosyncratically shown serious divergences in a number of the convergence and performance measures.

76 FR 11509 - Brass Sheet and Strip From France, Germany, Italy, and Japan

Science.gov (United States)

2011-03-02

...)] Brass Sheet and Strip From France, Germany, Italy, and Japan AGENCY: United States International Trade... and strip from France, Germany, Italy, and Japan. SUMMARY: The Commission hereby gives notice that it... France, Germany, Italy, and Japan would be likely to lead to continuation or recurrence of material...

Documents and legal texts: Australia, Germany, Sweden

International Nuclear Information System (INIS)

Anon.

2012-01-01

Australia: National Radioactive Waste Management Act 2012 No. 29, 2012 (An Act to make provision in relation to the selection of a site for, and the establishment and operation of, a radioactive waste management facility, and for related purposes). Germany: Act on the Peaceful Utilisation of Atomic Energy and the Protection against its Hazards (Atomic Energy Act) of 23 December 1959, as amended and promulgated on 15 July 1985, last amendment by the Act of 8 November 2011. Sweden: The Swedish Radiation Safety Authority's regulations concerning clearance of materials, rooms, buildings and land in practices involving ionising radiation (Swedish Radiation Safety Authority Regulatory Code issued on 20 October 2011, Published on 2 November 2011); The Swedish Radiation Safety Authority's general advice on the application of the regulations concerning clearance of materials, rooms, buildings and land in practices involving ionising radiation (issued on 20 October 2011)

sup 8 He- sup 6 He a comparative study of electromagnetic fragmentation reactions

CERN Document Server

Meister, M; Aleksandrov, D.; Aumann, T.; Baumann, T.; Borge, M.J.G.; Chulkov, L.V.; Cortina-Gil, D.; Eberlein, B.; Elze, Th.W.; Emling, H.; Geissel, H.; Hellström, M.; Jonson, B.; Kratz, J.V.; Kulessa, R.; Leistenschneider, A.; Mukha, I.; Münzenberg, G.; Nickel, F.; Nilsson, T.; Nyman, G.; Pfützner, M.; Pribora, V.; Richter, A.; Riisager, K.; Scheidenberger, C.; Schrieder, G.; Simon, H.; Tengblad, O.; Zhukov, M.V.

2002-01-01

Dissociation of a 227 MeV/u sup 8 He beam in a lead target has been studied in a kinematically complete experiment. The results are compared with similar data from the well-known halo nucleus sup 6 He. Coulomb-nuclear interference in the inelastic channel gives evidence for a I suppi=1 sup - resonance in sup 8 He at E sub x =4.15 MeV. The deduced B(E1) value of 0.38+-0.07 e sup 2 fm sup 2 indicates a uniform distribution of the four neutrons around the alpha-particle core.

Opening speech annual meeting on nuclear technology 2013, 14 to 16 May 2013, Berlin, Germany

Energy Technology Data Exchange (ETDEWEB)

Gueldner, Ralf [Deutsches Atomforum e.V. (DAtF), Berlin (Germany)

2013-07-15

Germany is an important location for nuclear technology also in the face of the 'Energiewende'. Our industry is not merely the object of political decisions, but it also continues to make its reliable and safe contribution to supplying energy and to this country's prosperity. The 9 nuclear power plants connected to the grid are a pillar of the energy supply especially for baseload generation, with an installed power of 12,700 MW at an average availability of over 90 %. With almost 100 billion kilowatt hours generated annually, they contributed 1/6 of the electricity generated in Germany in 2012 and made Germany the second largest nuclear power producer in the European Union. The nuclear power plants ensure, as do the other large power plants, the regional voltage and frequency stability and with their good controllability and the large standard service volume make an important contribution to integrating the production of electricity from renewables which is very high by international comparison. Nuclear technology in Germany is not restricted to the dismantling, final storage and remaining operations of plants, but rather it is made up of a vigorous, competitive nuclear industry that is among the best in the world. That does not merely show in the ranking of the nuclear power plants with the highest output rates, which placed 4 German plants in the top ten in the world also in 2012. It also becomes apparent when nuclear technology Made in Germany is sought after all over the world, in particular where the level of safety is concerned, e.g. worldwide in improving the safety of plants after the accident at Fukushima. Quite a number of safety components that are just being ordered elsewhere have been tried and tested for years already in Germany, and are supplied, installed and serviced by German suppliers and service providers. The broad range of the nuclear industry in Germany and its backing in a diverse research landscape means that the products

Homozygous familial hypercholesterolemia (HoFH in Germany: an epidemiological survey

Directory of Open Access Journals (Sweden)

Walzer S

2013-05-01

Full Text Available S Walzer,1 K Travers,2 S Rieder,3 E Erazo-Fischer,3 D Matusiewicz41MArS Market Access and Pricing Strategy UG (hb, Weil am Rhein, Germany; 2United Biosource Corporation, Lexington, USA; 3Alcimed GmbH, Cologne, Germany; 4Institute for Health Care Management and Research, Faculty of Economics and Business Administration, University of Duisburg-Essen, Essen, GermanyIntroduction: In Europe a disease is recognized as rare if less than 1 in 2000 people suffer from the specific disease. In patients with familial homozygous hypercholesterolemia (HoFH the accumulation of low-density lipoprotein cholesterol (LDL-C leads to generalized atherosclerosis due to an insufficient functioning of the LDL-C receptors. Patients die early sometimes even in the mid-30s, from myocardial infarction or stroke. For the German population, insufficient epidemiological evidence exists.Methods: A systematic literature search in EMBASE and Medline was performed in conjunction with a targeted manual search for epidemiological HoFH studies. Additionally a nationwide survey was conducted in Germany in all identified apheresis- and lipid centers. The purpose of the survey was the validation of the systematic literature search results based on empirical (practice data.Results: In total 961 publications were found, 874 were excluded based on pre-defined exclusion criteria leaving only 87 for further review. After review of the identified abstracts (n = 87 23 publications were identified as epidemiological studies. Only one publication was found which reported a prevalence of 1:1,000,000. The qualitative survey among 187 physicians in Germany also revealed a low prevalence: 95 HoFH patients were identified in 35 centers.Conclusion: The estimated frequency of homozygous familial hypercholesterolemia patients in Germany is around 95 (1:860,000 and the disease should be recognized as rare according to the definition of the European Medical Agency.Keywords: epidemiology, homozygous

2,2′-Bis{8-[(benzylaminomethylidene]-1,6-dihydroxy-5-isopropyl-3-methylnaphthalen-7(8H-one}

Directory of Open Access Journals (Sweden)

Shukhrat M. Hakberdiev

2013-11-01

Full Text Available The asymmetric unit of the title compound, C44H44N2O6, contains two independent molecules with similar conformations. The dihydronaphthalene ring systems are approximately planar [maximum deviations = 0.036 (2, 0.128 (2, 0.0.24 (2 and 0.075 (2 Å]. The dihedral angle between two dihydronaphthalene ring systems is 83.37 (4° in one molecule and 88.99 (4° in the other. The carbonyl O atom is linked with the adjacent hydroxy and imino groups via intramolecular O—H...O and N—H...O hydrogen bonds. In the crystal, molecules are linked through O—H...O hydrogen bonds into layers parallel to (001, and adjacent layers are further stacked by π–π interactions between dihydronaphthalene and phenyl rings into a three-dimensional supramolecular architecture. In the crystal, one of the isopropyl groups is disordered over two positions with an occupancy ratio of 0.684 (8:0.316 (8.

Phenylketonuria is not a risk factor for changes of inflammation status as assessed by interleukin 6 and interleukin 8 concentrations.

Science.gov (United States)

Mozrzymas, Renata; Duś-Żuchowska, Monika; Kałużny, Łukasz; Wenska-Chyży, Ewa; Walkowiak, Jarosław

2016-01-01

High oxidative stress and a reduced potential for free radical scavenging in phenylketonuria (PKU) patients, a phenomenon confirmed in a few studies, may lead to systemic chronic inflammation. The aim of this study was to compare the inflammation status, as assessed by interleukin 6 and interleukin 8 concentrations, in patients with PKU and in healthy controls. Twenty patients with classical PKU, aged 18-34 years and under dietary control, were enrolled in the study. The control group comprised of 20 healthy subjects matched for age and sex. Interleukin 6 and 8 levels were measured by enzyme-linked immunosorbent assay (ELISA) kits in all study participants. IL-6 concentrations in the study group ranged from 0.74 pg/ml to 1.34 pg/ml. No significant differences were found between IL-6 concentration between the study group and the control group (p = 0.989). IL-8 concentrations ranged from 17.56 pg/ml to 20.87 pg/ml. The obtained results of IL-8 levels did not differ significantly between the study group and control group (p = 0.192). No significant correlation was observed between Phe blood levels and IL-6 or IL-8 concentrations in the study group (ρ respectively: -0.225, 0.177). In a multivariate analysis, neither IL-6 nor IL-8 concentrations were correlated with sex, age, BMI and Phe levels. Phenylketonuria is not a risk factor for changes of inflammation status as assessed by IL-6 and IL-8 concentrations.

Problems of Economic Development in Reunified Germany. Retrospective Approach

Directory of Open Access Journals (Sweden)

Marta Gotz

2011-07-01

Full Text Available Does Eastern Germany differ significantly from Western part in economic terms? How have new Bundeslnder been developing over past twenty years? How fast has East been catching up with West? What could have hampered convergence? How today are German states equipped with factors determining future growth? How the new Bundeslnder performed do compared with the old ones? This paper seeks to address above mentioned questions. It offers a comprehensive review of key economic developments of two decades of reunited Germany. Particularly it examines current economic landscape; investigates convergence processes taking place since reunification and tries to identify most likely impediments hampering full catching up. Finally, it aims at assessing contemporary growth potential of German states. With respect to the starting point poor performance of East Germany back in 1990 the progress made and results achieved are impressive. Though, comparing the situation with Western part of the country significant discrepancies continue to exist. Certainly, assessment of the last twenty years of reunited Germany hinges much upon perspective taken. Two decades after Berlin Wall Fall opinions on economic consequences of reunification are more balanced, since much has been achieved, but much still needs to be done.

Investigation of the fabrication process of hot-worked stainless-steel and Mo sheathed PbMo6 S8 wires

International Nuclear Information System (INIS)

Yamasaki, H.; Kimura, Y.

1988-01-01

Stainless-steel and Mo sheathed PbMo 6 S 8 wires have been fabricated by hot working from modified PbS, Mo, and MoS 2 mixed powders which were prepared by reacting Pb, Mo, and S at 530 0 C. Critical current densities were investigated for different preparation conditions, and it is revealed that obtaining continuous current path between PbMo 6 S 8 grains is the most important factor to achieve high critical current density. The J/sub c/ value of 2.8 x 10 4 Acm 2 (8 T), 7.8 x 10 3 Acm 2 (15 T), and 1.3 x 10 3 Acm 2 (23 T) was observed for the PbMo 6 S/sub 7.0/ wire heat treated at 700 0 C.copic

Risk of second primary cancers after testicular cancer in East and West Germany: A focus on contralateral testicular cancers

Science.gov (United States)

Rusner, Carsten; Streller, Brigitte; Stegmaier, Christa; Trocchi, Pietro; Kuss, Oliver; McGlynn, Katherine A; Trabert, Britton; Stang, Andreas

2014-01-01

Testicular cancer survival rates improved dramatically after cisplatin-based therapy was introduced in the 1970s. However, chemotherapy and radiation therapy are potentially carcinogenic. The purpose of this study was to estimate the risk of developing second primary cancers including the risk associated with primary histologic type (seminoma and non-seminoma) among testicular cancer survivors in Germany. We identified 16 990 and 1401 cases of testicular cancer in population-based cancer registries of East Germany (1961–1989 and 1996–2008) and Saarland (a federal state in West Germany; 1970–2008), respectively. We estimated the risk of a second primary cancer using standardized incidence ratios (SIRs) with 95% confidence intervals (95% CIs). To determine trends, we plotted model-based estimated annual SIRs. In East Germany, a total of 301 second primary cancers of any location were observed between 1961 and 1989 (SIR: 1.9; 95% CI: 1.7–2.1), and 159 cancers (any location) were observed between 1996 and 2008 (SIR: 1.7; 95% CI: 1.4–2.0). The SIRs for contralateral testicular cancer were increased in the registries with a range from 6.0 in Saarland to 13.9 in East Germany. The SIR for seminoma, in particular, was higher in East Germany compared to the other registries. We observed constant trends in the model-based SIRs for contralateral testicular cancers. The majority of reported SIRs of other cancer sites including histology-specific risks showed low precisions of estimated effects, likely due to small sample sizes. Testicular cancer patients are at increased risk especially for cancers of the contralateral testis and should receive intensive follow-ups. PMID:24407180

Hiroshima - Monday August 6, 1945, 8h15 a.m

International Nuclear Information System (INIS)

Hersey, John; Belmont, Georges; Haas, Pascale

2011-01-01

On 6 August 1945 at 8.15 a.m., Hiroshima was destroyed by the first atom bomb ever dropped on a city, killing one hundred thousand men, women and children in its white fury. This book, John Hersey's journalistic masterpiece, tells what happened on that day. Told through the memories of six civilians who survived against the odds, this timeless, powerful and compassionate document tells the moments that have preceded and followed the atomic explosion. John Hersey's spare, devastating report on the attack was first published in the New Yorker in 1946. Written in the immediate aftermath of the disaster, it is a classic piece of journalism, and a defining moment of the nuclear age

The impact on human health and the environment of different types of German and Polish power plants. A first scoring approach in Germany

International Nuclear Information System (INIS)

Voigt, Kristina; Scherb, Hagen; Bartoszczuk, Pawel

2014-01-01

This paper gives a short overview about the types of power stations in Germany and Poland. The energy production in Germany in 2012 was 629,7 TWh. Every type of power plant poses a risk to humans and the environment but in a different way and to a different extent. A discrete mathematical method, named Hasse diagram technique is applied. The software package used is the PyHasse software. A first ranking approach is presented taking the 8 most used types of power plants in Germany into account and ranking those applying 5 different evaluation criteria, including 3 environmental health attributes. In this first approach not only nuclear power stations but also coal-driven power stations come worst in this ranking method. Renewable energies come best in our approach. Unfortunately their percentage of the overall energy production is still too low (about 22,1 % in Germany and 10,4 % in Poland). This underlines the necessity for urgently supporting the development of renewable energy power plants. Furthermore, we plan to extend our scoring approach to other European countries, starting with the neighboring country Poland.

The impact on human health and the environment of different types of German and Polish power plants. A first scoring approach in Germany

Energy Technology Data Exchange (ETDEWEB)

Voigt, Kristina; Scherb, Hagen [Helmholtz Zentrum Muenchen, Neuherberg (Germany). Inst. of Computational Biology; Bartoszczuk, Pawel [Warsaw School of Economics (Poland). Enterprise Inst.

2014-07-01

This paper gives a short overview about the types of power stations in Germany and Poland. The energy production in Germany in 2012 was 629,7 TWh. Every type of power plant poses a risk to humans and the environment but in a different way and to a different extent. A discrete mathematical method, named Hasse diagram technique is applied. The software package used is the PyHasse software. A first ranking approach is presented taking the 8 most used types of power plants in Germany into account and ranking those applying 5 different evaluation criteria, including 3 environmental health attributes. In this first approach not only nuclear power stations but also coal-driven power stations come worst in this ranking method. Renewable energies come best in our approach. Unfortunately their percentage of the overall energy production is still too low (about 22,1 % in Germany and 10,4 % in Poland). This underlines the necessity for urgently supporting the development of renewable energy power plants. Furthermore, we plan to extend our scoring approach to other European countries, starting with the neighboring country Poland.

11th Annual Mine Warfare Technology Symposium, May 6-8, 2014 - Monterey, CA

OpenAIRE

2014-01-01

The Naval Postgraduate School (NPS), the Office of Naval Research (ONR), the Program Executive Office Littoral Combat Ships (PEO LCS), OPNAV (N95), and The Consortium for Robotics and Unmanned Systems Education and Research (CRUSER) are pleased to announce the ELEVENTH International Mine Warfare Technology Symposium in Monterey, California, May 6-8, 2014.

Interaction mechanisms of ionic liquids [Cnmim]Br (n=4, 6, 8, 10) with bovine serum albumin

International Nuclear Information System (INIS)

Yan Hua; Wu Junyong; Dai Guoliang; Zhong Aiguo; Chen Hao; Yang Jianguo; Han Deman

2012-01-01

It is important to study the interaction of ionic liquids (ILs) with protein for the applications of ILs in biochemical process, and help the researchers to choose and design the better ILs to serve as a solvent. In this work, the interaction between 1-alkyl-3-methylimidazolium bromide [C n mim]Br (n=4, 6, 8, 10) and bovine serum albumin (BSA) was systematically investigated for the first time by multi-spectroscopic approach (fluorescence, UV–vis and FT-IR spectroscopy) and density functional theory (DFT). [C n mim]Br (n=4, 6, 8, 10) can bind to BSA by H-bond interaction between their cationic headgroups and Asp/Glu amino acid residue at the surface of BSA, and hydrophobic interaction between their hydrocarbon chains and the hydrophobic amino acid residues in the interior of BSA. On the basis of thermodynamic parameters and the similar structure of [C n mim]Br (n=4, 6, 8, 10), it can be inferred that the hydrophobic interaction plays a major role in the interaction of [C 10 mim]Br with BSA, while the hydrogen bond and van der Waals force play a major role in the interaction of [C n mim]Br (n=4, 6, 8) with BSA. Synchronous fluorescence and FT-IR spectra indicate that [C 10 mim]Br could markedly change the secondary structure of BSA, while [C n mim]Br (n=4, 6, 8) could slightly change the secondary structure of BSA. The results allowed us to understand (i) the effect of the alkyl chain length of the cation on the mechanism of ILs–protein interaction and (ii) the effect of the alkyl chain length of the cation on the protein secondary structure. - Highlights: ► Interaction of [C n mim]Br with BSA was investigated by spectroscopy and DFT. ► Interaction mechanisms and BSA secondary structure were discussed. ► Effects of the alkyl chain length of cation were presented.

Increased incidence of syphilis in men who have sex with men and risk management strategies, Germany, 2015.

Science.gov (United States)

Jansen, Klaus; Schmidt, Axel J; Drewes, Jochen; Bremer, Viviane; Marcus, Ulrich

2016-10-27

In Germany, the number of reported syphilis cases increased between 11% and 22% per year between 2010 and 2014. We analysed syphilis surveillance data and data of four behavioural surveys on men who have sex with men (MSM) in Germany (2003, 2007, 2010, 2013) to assess if this rise is ongoing and to find possible explanations for it. Syphilis notifications increased in 2015 by 19% to a total of 6,834. This was mainly due to increasing notifications in MSM of all age groups in larger German cities. Data from the behavioural surveys on MSM in Germany showed a simultaneous increase of selective condom use as HIV-status-bases risk management strategy and the number of syphilis cases. MSM diagnosed with HIV reported condomless anal intercourse with non-steady partners more frequent than MSM not diagnosed with HIV or untested for HIV, but the latter also reported higher frequencies of this behaviour in the more recent surveys. Transmission in HIV-positive MSM probably plays an important, but not exclusive role, for the syphilis dynamics in Germany. A risk adapted routine screening for sexually active MSM and potentially innovative approaches to increase early screening and treatment of syphilis such as internet counselling, home sampling, home testing and broadening venue-based (rapid) testing, should be critically evaluated to effectively reduce syphilis infections. This article is copyright of The Authors, 2016.

The α1,6-fucosyltransferase gene (fut8 from the Sf9 lepidopteran insect cell line: insights into fut8 evolution.

Directory of Open Access Journals (Sweden)

Sylvie Juliant

Full Text Available The core alpha1,6-fucosyltransferase (FUT8 catalyzes the transfer of a fucosyl moiety from GDP-fucose to the innermost asparagine-linked N-acetylglucosamine residue of glycoproteins. In mammals, this glycosylation has an important function in many fundamental biological processes and although no essential role has been demonstrated yet in all animals, FUT8 amino acid (aa sequence and FUT8 activity are very well conserved throughout the animal kingdom. We have cloned the cDNA and the complete gene encoding the FUT8 in the Sf9 (Spodoptera frugiperda lepidopteran cell line. As in most animal genomes, fut8 is a single-copy gene organized in different exons. The open reading frame contains 12 exons, a characteristic that seems to be shared by all lepidopteran fut8 genes. We chose to study the gene structure as a way to characterize the evolutionary relationships of the fut8 genes in metazoans. Analysis of the intron-exon organization in 56 fut8 orthologs allowed us to propose a model for fut8 evolution in metazoans. The presence of a highly variable number of exons in metazoan fut8 genes suggests a complex evolutionary history with many intron gain and loss events, particularly in arthropods, but not in chordata. Moreover, despite the high conservation of lepidoptera FUT8 sequences also in vertebrates and hymenoptera, the exon-intron organization of hymenoptera fut8 genes is order-specific with no shared exons. This feature suggests that the observed intron losses and gains may be linked to evolutionary innovations, such as the appearance of new orders.

R dump converter without DC link capacitor for an 8/6 SRM: experimental investigation.

Science.gov (United States)

Kavitha, Pasumalaithevan; Umamaheswari, Bhaskaran

2015-01-01

The objective of this paper is to investigate the performance of 8/6 switched reluctance motor (SRM) when excited with sinusoidal voltage. The conventional R dump converter provides DC excitation with the help of capacitor. In this paper the converter used is the modified R dump converter without DC link capacitor providing AC or sinusoidal excitation. Torque ripple and speed ripple are investigated based on hysteresis current control. Constant and sinusoidal current references are considered for comparison in both DC and AC excitation. Extensive theoretical and experimental investigations are made to bring out the merits and demerits of AC versus DC excitation. It is shown that the constructionally simple SRM can be favorably controlled with simple R dump converter with direct AC excitation without need for DC link capacitor. A 4-phase 8/6 0.5 kW SRM is used for experimentation.

Epidemiology in Germany-general development and personal experience.

Science.gov (United States)

Wichmann, Heinz-Erich

2017-08-01

Did you ever hear about epidemiology in Germany? Starting from an epidemiological desert the discipline has grown remarkably, especially during the last 10-15 years: research institutes have been established, research funding has improved, multiple curriculae in Epidemiology and Public Health are offered. This increase has been quite steep, and now the epidemiological infrastructure is much better. Several medium-sized and even big population cohorts are ongoing, and the number and quality of publications from German epidemiologists has reached a respectable level. My own career in epidemiology started in the field of environmental health. After German reunification I concentrated for many years on environmental problems in East Germany and observed the health benefits after improvement of the situation. Later, I concentrated on population-based cohorts in newborns (GINI/LISA) and adults (KORA, German National Cohort), and on biobanking. This Essay describes the development in Germany after worldwar 2, illustrated by examples of research results and build-up of epidemiological infractructures worth mentioning.

Experience with the SE in Germany

Directory of Open Access Journals (Sweden)

Jochem Reichert

2008-03-01

Full Text Available A rather significant proportion of the Societas Europaeas (the European Company, or SE formed to date have had German roots. German corporate law has been enriched by an interesting alternative which meanwhile seems to have gained momentum. This contribution focuses on SEs incorporated by German entrepreneurs and provides an interesting account concerning the use of SEs in Germany in practice, such as Allianz, Fresenius, BASF and Porsche. Has the SE been used to circumvent rigid company law provisions or is it a more flexible and effective tool, perhaps, for company mobility? The practical motives behind setting up this company form are also reflected upon. These include: the facilitation of cross-border mergers; transfer of the registered office; the ‘European’ image; a more flexible form of co-determination in large companies (reduction of the number of supervisory board members; avoidance and freezing of co-determination for medium-sized enterprises; the appeal of the one-tier system and its endangerment by German co-determination; and flat and uniform structures for company groups. The author also briefly discusses some of the problems arising from the formation of SEs in Germany. He ultimately concludes that practice has shown that it is possible to work with the legal regime of the SE in Germany, which adds a new company form to those available in that Member State.

The changing consumer in Germany

DEFF Research Database (Denmark)

Grunert, Klaus G.; Grunert, Suzanne C.; Glatzer, Wolfgang

1995-01-01

Changes in economic, demographic, and cultural factors in West Germany during the past decades are briefly described, as well as changes in consumption patterns and the way the major marketing variables have been used and implemented. Special atte is paid to the upheavals caused by the German...

Urban Growth in a Fragmented Landscape: Estimating the Relationship between Landscape Pattern and Urban Land Use Change in Germany, 2000-2006

Science.gov (United States)

Keller, R.

2013-12-01

One of the highest priorities in the conservation and management of biodiversity, natural resources and other vital ecosystem services is the assessment of the mechanisms that drive urban land use change. Using key landscape indicators, this study addresses why urban land increased 6 percent overall in Germany from 2000-2006. Building on regional science and economic geography research, I develop a model of landscape change that integrates remotely sensed and other geospatial data, and socioeconomic data in a spatial autoregressive model to explain the variance in urban land use change observed in German kreise (counties) over the past decade. The results reveal three key landscape mechanisms that drive urban land use change across Germany, aligning with those observed in US studies: (1) the level of fragmentation, (2) the share of designated protected areas, and (3) the share of prime soil. First, as fragmentation of once continuous habitats in the landscape increases, extensive urban growth follows. Second, designated protected areas have the perverse effect of hastening urbanization in surrounding areas. Third, greater shares of prime, productive soil experienced less urban land take over the 6 year period, an effect that is stronger in the former East Germany, where the agricultural sector remains large. The results suggest that policy makers concentrate their conservation efforts on preexisting fragmented land with high shares of protected areas in Germany to effectively stem urban land take. Given that comparative studies of land use change are vital for the scientific community to grasp the wider global process of urbanization and coincident ecological impacts, the methodology employed here is easily exportable to land cover and land use research programs in other fields and geographic areas. Key words: Urban land use change, Ecosystem services, Landscape fragmentation, Remote sensing, Spatial regression models, GermanyOLS and Spatial Autoregressive Model

Energy supply in East Germany

Energy Technology Data Exchange (ETDEWEB)

Shimoyama, Tsutomu

1988-07-10

East Germany has abundant brown coal, about 90.4% of primary energy production in 1986. The high dependence upon brown coal has been established since its reevaluation in 1980 and the production is reaching a peak. Its share in power generation is also as high as 83.3% in the year. Therefore, the energy sufficiency of East Germany is about 80%. Problems are arising, however, in deterioration of excavation conditions and coal quality. Domestic energy resources such as the uranium and natural gas are also used to the maximum extent. The nuclear power has about 10% of share in the power generation. The share expansion policy is seemingly maintained even after the accident of Chernoble. Exploration, excavation and reprocessing of the uranium are conducted under the leadership of USSR. The country depends upon the oil in a very low level, less than 1%, as a result of the energy conservation policy in 1980's. (1 fig, 5 tabs)

Fire Risk Assessment in Germany

International Nuclear Information System (INIS)

Berg, H. P.

2000-01-01

Quantitative fire risk assessment can serve as an additional tool to assess the safety level of a nuclear power plant (NPP) and to set priorities for fire protection improvement measures. The recommended approach to be applied within periodic safety reviews of NPPs in Germany starts with a screening process providing critical fire zones in which a fully developed fire has the potential to both cause an initiating event and impair the function of at least one component or system critical to safety. The second step is to perform a quantitative analysis using a standard event tree has been developed with elements for fire initiation, ventilation of the room, fire detection, fire suppression, and fire propagation. In a final step, the fire induced frequency of initiating events, the main contributors and the calculated hazard state frequency for the fire event are determined. Results of the first quantitative fire risk studies performed in Germany are reported. (author)

Regulatory strategies for selected Member States (Denmark, Germany, Netherlands, Spain, the UK)

Energy Technology Data Exchange (ETDEWEB)

Nieuwenhout, F.D.J.; Jansen, J.C.; Van der Welle, A.J. [ECN Policy Studies, Petten (Netherlands); Olmos, L.; Cossent, R.; Gomez, T. [Universidad Pontificia Comillas, Madrid (Spain); Poot, J.; Bongaerts, M. [Liander, Duiven (Netherlands); Trebolle, D. [Union Fenosa Distribucion, Madrid (Spain); Doersam, B. [MVV Energie, Mannheim (Germany); Bofinger, S.; Lichtner, P.; Gerhardt, N. [Fraunhofer Institute for Wind Energy and Energy System Technology, IWES, Bremerhaven (Germany); Jacobsen, H.; Ropenus, S.; Schroeder, S. [Risoe National Laboratory for Sustainable Energy, Technical University of Denmark DTU, Roskilde (Denmark); Auer, H.; Weissensteiner, L.; Prueggler, W.; Obersteiner, C.; Zach, K. [Energy Economics Group EEG, Vienna University of Technology, Vienna (Austria)

2010-05-15

This Work Package 6 report of the IMPROGRES project provides an overview of regulatory strategies and incentives, conducive to (1) network integration of increasing levels of distributed generation including notably intermittent renewable technology such as wind power and solar photovoltaics (PV) as well as (2) options for reducing impacts on surging network integration costs. Similar to the IMPROGRES project in general, this report focuses on European distribution networks. It includes specific country studies of Denmark, Germany, the Netherlands, Spain and the UK.

The Relation between Contingency Preference and Imitation in 6-8-Month-Old Infants

Science.gov (United States)

Klein-Radukic, Sarah; Zmyj, Norbert

2016-01-01

Detecting self-generated actions and imitating other-generated actions are important abilities in order to interact with others. The relationship between these domains was investigated in 6-8-month-old infants. In a contingency-preference task, infants observed their own legs on a real-time and a delayed video display. In an imitation task, the…

Tsunamis from strike-slip earthquakes in the Wharton Basin, northeast Indian Ocean: March 2016 Mw7.8 event and its relationship with the April 2012 Mw 8.6 event

Science.gov (United States)

Heidarzadeh, Mohammad; Harada, Tomoya; Satake, Kenji; Ishibe, Takeo; Takagawa, Tomohiro

2017-12-01

The Wharton Basin, off southwest Sumatra, ruptured to a large intraplate left-lateral strike-slip Mw 7.8 earthquake on 2016 March 2. The epicentre was located ∼800 km to the south of another similar-mechanism intraplate Mw 8.6 earthquake in the same basin on 2012 April 11. Small tsunamis from these strike-slip earthquakes were registered with maximum amplitudes of 0.5-1.5 cm on DARTs and 1-19 cm on tide gauges for the 2016 event, and the respective values of 0.5-6 and 6-40 cm for the 2012 event. By using both teleseismic body waves and tsunami observations of the 2016 event, we obtained optimum slip models with rupture velocity (Vr) in the range of 2.8-3.6 km s-1 belonging to both EW and NS faults. While the EW fault plane cannot be fully ruled out, we chose the best model as the NS fault plane with a Vr of 3.6 km s-1, a maximum slip of 7.7 m and source duration of 33 s. The tsunami energy period bands were 4-15 and 7-24 min for the 2016 and 2012 tsunamis, respectively, reflecting the difference in source sizes. Seismicity in the Wharton Basin is dominated by large strike-slip events including the 2012 (Mw 8.6 and 8.2) and 2016 (Mw 7.8) events, indicating that these events are possible tsunami sources in the Wharton Basin. Cumulative number and cumulative seismic-moment curves revealed that most earthquakes are of strike-slip mechanisms and the largest seismic-moment is provided by the strike-slip earthquakes in this basin.

77 FR 23508 - Brass Sheet and Strip From France, Germany, Italy, and Japan

Science.gov (United States)

2012-04-19

...)] Brass Sheet and Strip From France, Germany, Italy, and Japan Determination On the basis of the record \\1... antidumping duty orders on brass sheet and strip from France, Germany, Italy, and Japan would be likely to... from France, Germany, Italy, and Japan: Investigation Nos. 731-TA-313, 314, 317, and 379 (Third Review...

Source Parameters of the 8 October, 2005 Mw7.6 Kashmir Earthquake

Science.gov (United States)

Mandal, Prantik; Chadha, R. K.; Kumar, N.; Raju, I. P.; Satyamurty, C.

2007-12-01

During the last six years, the National Geophysical Research Institute, Hyderabad has established a semi-permanent seismological network of 5 broadband seismographs and 10 accelerographs in the Kachchh seismic zone, Gujarat, with the prime objective to monitor the continued aftershock activity of the 2001 Mw7.7 Bhuj mainshock. The reliable and accurate broadband data for the Mw 7.6 (8 Oct., 2005) Kashmir earthquake and its aftershocks from this network, as well as from the Hyderabad Geoscope station, enabled us to estimate the group velocity dispersion characteristics and the one-dimensional regional shear-velocity structure of peninsular India. Firstly, we measure Rayleigh- and Love-wave group velocity dispersion curves in the range of 8 to 35 sec and invert these curves to estimate the crustal and upper mantle structure below the western part of peninsular India. Our best model suggests a two-layered crust: The upper crust is 13.8-km thick with a shear velocity (Vs) of 3.2 km/s; the corresponding values for the lower crust are 24.9 km and 3.7 km/sec. The shear velocity for the upper mantle is found to be 4.65 km/sec. Based on this structure, we perform a moment tensor (MT) inversion of the bandpass (0.05 0.02 Hz) filtered seismograms of the Kashmir earthquake. The best fit is obtained for a source located at a depth of 30 km, with a seismic moment, Mo, of 1.6 × 1027 dyne-cm, and a focal mechanism with strike 19.5°, dip 42°, and rake 167°. The long-period magnitude (MA ~ Mw) of this earthquake is estimated to be 7.31. An analysis of well-developed sPn and sSn regional crustal phases from the bandpassed (0.02 0.25 Hz) seismograms of this earthquake at four stations in Kachchh suggests a focal depth of 30.8 km.

Proceedings of Japan-Germany Workshop of Bioremediation; Nichidoku bio remediation workshop hokokusho

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-12-04

This is a proceedings of Japan-Germany Workshop on Bioremediation held on December 4 and 5, 1995. The keynote lectures include `Environmental preservation using biotechnology` by Prof. Karube of University of Tokyo, and `Environmental technology in Germany: status, achievements, and problems` by Prof. R.D.Schmid of University of Stuttgart. In the oral session, 7 papers are presented in the microbiological aspects of bioremediation, 10 papers in the environmental monitoring, and 6 papers in the engineering aspects of bioremediation. This workshop was sponsored by the German Federal Ministry for Education, Science and Technology, New Energy and Industrial Technology Development Organization, and Research Institute of Innovative Technology for the Earth. According to the lecture by Prof. Karube, key technologies for the environmental preservation include biotechnologies, such as the culture of fine algae with high CO2 concentration resistant properties using a solar light condenser, production of effective substances from CO2, and production of organic fertilizer from the sediments of lakes and sea. 19 refs., 12 figs., 3 tabs.

The Reaction of West Germany to Soviet-American negotiations 1968-1972

Directory of Open Access Journals (Sweden)

Katerina Alexandrovna Borisova

2015-12-01

Full Text Available This article is devoted to the analyzing of the reaction of Germany to the Strategic Arms Limitation Talks (SALT in the late 60's - early 70’s. Our attention is paid to the characteristics of executive and legislative authorities’ decisions of Germany. After Berlin and Cuban missiles crisis constant threat of a nuclear missile stability promoted the development of SALT, which should be the basic element of balance of power for the survival of human civilization. For all western countries searching for the formula to avoid the escalation of all-out war had to be based on the main principles of international relations in the context of detent of geo-political tensions between the Soviet Union and the United States. But for a long period of time West Germany still to be on the position of cold war confrontation. Such a policy could lead Germany to political isolation. After first successful steps of soviet-american’s negotiations West Germany began to realize the threat of its isolation and tried to integrate itself in the general process of detent, first of all in the field of European security. Main purpose of this research is analyzing specific mechanisms of transformation of the bilateral relations between United States and Germany, comparing different foreign policies with socialistic block, studying contradictions in the capitalist block and to identify and classify these differences, as well.

Manual: Renewable Energy Sources in Germany; Handbuch Regenerative Energiequellen in Deutschland

Energy Technology Data Exchange (ETDEWEB)

Heimann, M.

2004-07-01

One of the measures to reduce CO2 is the utilization of renewable energies. Meanwhile, Germany has come to play a leading role worldwide in this subject and is the world leader especially regarding the use of wind and solar energy. The manual called ''Renewable Energy Sources in Germany'' shows the present state of the importance of renewable energies in Germany and describes the possibilities and future potentials for the future. The author describes the ways of utilizing renewable energies in a very comprehensive manner. He assesses the medium and long-term chances of renewable energies realistically from a neutral point of view, giving the readers a well-founded basis to build their own opinions about the subject. Thus the book makes a good contribution to rationalize the discussion on renewable energies which often is lead in an emotional way. The book covers following chapters: 1) Renewable energy sources in Germany 2) Basic data on renewable energies in Germany 3) Renewable energy source in building techniques 4) Power plant and thermal plant techniques of renewable energy sources 5) Evaluation methods for renewable energies in energy supply.

Jung's views of Nazi Germany: the first year and Jung's transition.

Science.gov (United States)

Schoenl, William; Schoenl, Linda

2016-09-01

This article first considers Jung's response to the coming to power of the Nazis in Germany. It brings forth evidence that, besides wanting to preserve psychotherapy in Germany and maintain the international connection between the German and other communities of psychotherapists, he wanted to advance Jungian psychology - his psychology - in Germany. It also presents evidence that, although he occasionally made some anti-Semitic statements during this early period, he was not anti-Semitic in the way the Nazis were. The paper then argues that after Gustav Bally's criticisms in the Neue Zuercher Zeitung in February 1934, Jung entered into a transitional period that spring during which he became warier both of the Nazis and of making any statements that could be construed as being anti-Semitic. Schoenl and Peck (2012) have shown how Jung's views of Nazi Germany changed from 1933 to March 1936. This present article demonstrates very significant changes in Jung's views during the important early part of this period, that is from January 1933 - when Hitler became Chancellor of Germany - through to the spring of 1934. It draws on evidence from archival and other primary sources. © 2016, The Society of Analytical Psychology.

Site characterization plan: Yucca Mountain Site, Nevada Research and Development Area, Nevada: Volume 6, Part B: Chapter 8, Sections 8.3.2 through 8.3.4.4

International Nuclear Information System (INIS)

1988-12-01

This site characterization plan (SCP) has been developed for the candidate repository site at Yucca Mountain in the State of Nevada. The SCP includes a description of the Yucca Mountain site (Chapters 1-5), a conceptual design for the repository (Chapter 6), a description of the packaging to be used for the waste to be emplaced in the repository (Chapter 7), and a description of the planned site characterization activities (Chapter 8). The schedules and milestones presented in Sections 8.3 and 8.5 of the SCP were developed to be consistent with the June 1988 draft Amendment to the DOE's Mission Plan for the Civilian Radioactive Waste Management Program. The five month delay in the scheduled start of exploratory shaft construction that was announced recently is not reflected in these schedules. 35 figs., 70 tabs

[Taxing unhealthy foods. A measure to promote public health in Germany?].

Science.gov (United States)

Lehnert, T; Riedel-Heller, S; König, H-H

2013-04-01

Due to the substantial health burden and costs caused by malnutrition in Germany, for instance as a result of obesity, diabetes, and cardiovascular diseases, the taxation of unhealthy foods/nutrients has been proposed as a possible health promoting measure. In order to evaluate whether such a fiscal intervention constitutes an effective and suitable measure to promote population health in Germany, the article outlines central empirical findings regarding malnutrition in Germany. Subsequently, the economic background (price elasticity of demand) is explained, and empirical evidence on the influence of changes in price on changes in consumption and health is presented. As a result of findings from the international literature being heterogeneous, and because very little research has been conducted in Germany on this matter until now, the taxation/subsidization of foods in order to promote population health is difficult to justify at this point.

Germany bars nuclear energy