WorldWideScience

Sample records for nusselt number induced

  1. Numerical modeling of the impact of regenerator housing on the determination of Nusselt numbers

    DEFF Research Database (Denmark)

    Nielsen, Kaspar Kirstein; Nellis, G.F.; Klein, S.A.

    2013-01-01

    It is suggested that the housing of regenerators may have a significant impact when experimentally determining Nusselt numbers at low Reynolds and large Prandtl numbers. In this paper, a numerical model that takes the regenerator housing into account as a domain that is thermally coupled to the r...

  2. Comparative study of Nusselt number for a single phase fluid flow using plate heat exchanger

    Directory of Open Access Journals (Sweden)

    Shanmugam Rajasekaran

    2016-01-01

    Full Text Available In this study, the plate heat exchangers are used for various applications in the industries for heat exchange process such as heating, cooling and condensation. The performance of plate heat exchanger depends on many factors such as flow arrangements, plate design, chevron angle, enlargement factor, type of fluid used, etc. The various Nusselt number correlations are developed by considering that the water as a working fluid. The main objective of the present work is to design the experimental set-up for a single phase fluid flow using plate heat exchanger and studied the heat transfer performance. The experiments are carried out for various Reynolds number between 500 and 2200, the heat transfer coefficients are estimated. Based on the experimental results the new correlation is developed for Nusselt number and compared with an existing correlation.

  3. Nusselt numbers of laminar, oscillating flows in stacks and regenerators with pores of arbitrary cross-sectional geometry.

    Science.gov (United States)

    Brady, John F

    2013-04-01

    Though widely used in steady-flow heat transfer applications, the Nusselt number-a dimensionless heat transfer coefficient-has not been studied as thoroughly in oscillating flows and is therefore not generally used in thermoacoustic applications. This paper presents expressions for the Nusselt numbers of laminar oscillating flows within the pores of stacks and regenerators, derived from thermoacoustic theory developed by Rott and Swift. These expressions are based on bulk (velocity-weighted, cross-sectionally averaged) temperature, rather than the cross-sectionally averaged temperature. Results are shown for parallel plates, circular pores, rectangular pores, and within the boundary layer limit. It is shown that bulk temperature does not become infinite during an acoustic cycle and that the Nusselt number is a complex constant at all times. In addition, steady-flow Nusselt numbers are recovered when velocity and temperature profiles are like those in steady flows.

  4. Nusselt Number Correlation for Vertical Tubes with Inverted Triangular Fins under Natural Convection

    Directory of Open Access Journals (Sweden)

    Byeong Dong Kang

    2017-08-01

    Full Text Available Vertical tubes with inverted triangular fins under natural convection are investigated experimentally. The thermal resistances of tubes with inverted triangular fins are measured for various fin numbers, fin heights, and heat inputs. A Nusselt number correlation that best predicts the measured thermal resistances is proposed. The proposed correlation is applicable to the following conditions: Rayleigh numbers of 1000–125,000, fin height to fin length ratios of 0.2–0.6, and fin numbers of 9–72. Finally, a contour map of the thermal resistances calculated from the proposed correlation for various fin thicknesses and fin numbers is presented. The contour map shows that there exist optimal values of the fin thickness and fin number at which the thermal resistance of the inverted-triangular-finned tube is minimized. Therefore, the proposed correlation enables a search for the optimal dimensions and has potential to be used in the designing of inverted-triangular-finned tubes of various cooling devices.

  5. Nusselt number evaluation for combined radiative and convective heat transfer in flow of gaseous products from combustion

    Directory of Open Access Journals (Sweden)

    Trabelsi Soraya

    2013-01-01

    Full Text Available Combined convection and radiation in simultaneously developing laminar flow and heat transfer is numerically considered with a discrete-direction method. Coupled heat transfer in absorbing emitting but not scattering gases is presented in some cases of practical situations such as combustion of natural gas, propane and heavy fuel. Numerical calculations are performed to evaluate the thermal radiation effects on heat transfer through combustion products flowing inside circular ducts. The radiative properties of the flowing gases are modeled by using the absorption distribution function (ADF model. The fluid is a mixture of carbon dioxide, water vapor, and nitrogen. The flow and energy balance equations are solved simultaneously with temperature dependent fluid properties. The bulk mean temperature variations and Nusselt numbers are shown for a uniform inlet temperature. Total, radiative and convective mean Nusselt numbers and their axial evolution for different gas mixtures produced by combustion with oxygen are explored.

  6. Local Nusselt number enhancement during gas-liquid Taylor bubble flow in a square mini-channel: An experimental study

    International Nuclear Information System (INIS)

    Majumder, Abhik; Mehta, Balkrishna; Khandekar, Sameer

    2013-01-01

    Taylor bubble flow takes place when two immiscible fluids (liquid-liquid or gas-liquid) flow inside a tube of capillary dimensions within specific range of volume flow ratios. In the slug flows where gas and liquid are two different phases, liquid slugs are separated by elongated Taylor bubbles. This singular flow pattern is observed in many engineering mini-/micro-scale devices like pulsating heat pipes, gas-liquid-solid monolithic reactors, micro-two-phase heat exchangers, digital micro-fluidics, micro-scale mass transfer process, fuel cells, etc. The unique and complex flow characteristics require understanding on local, as well as global, spatio-temporal scales. In the present work, the axial stream-wise profile of the fluid and wall temperature for air-water (i) isolated single Taylor bubble and, (ii) a train of Taylor bubbles, in a horizontal square channel of size 3.3 mm x 3.3 mm x 350 mm, heated from the bottom (heated length = 175 mm), with the other three sides kept insulated, are reported at different gas volume flow ratios. The primary aim is to study the enhancement of heat transfer due to the Taylor bubble train flow, in comparison with thermally developing single-phase flows. Intrusion of a bubble in the liquid flow drastically changes the local temperature profiles. The axial distribution of time-averaged local Nusselt number (Nu z ) shows that Taylor bubble train regime increases the transport of heat up to 1.2-1.6 times more as compared with laminar single-phase liquid flow. In addition, for a given liquid flow Reynolds number, the heat transfer enhancement is a function of the geometrical parameters of the unit cell, i.e., the length of adjacent gas bubble and water plug. (authors)

  7. Nusselt correlation to predict heat transfer from an oscillated vertical annular fluid column through a porous domain

    Science.gov (United States)

    Sayar, Ersin; Sari, Ugurcan

    2017-04-01

    Experimental evaluation of the heat transfer in oscillating flow under the constant heat flux and constant amplitude fluid displacement conditions is presented for a vertical annular flow through a stainless steel wool porous media. The analysis is carried out for two different heat fluxes and for five different frequencies. The data is acquired from the measurements both in the initial transient period and in the pseudo-steady (cyclic) period by the system. The physical and mathematical behavior of the resulting Nusselt numbers are analyzed, according to data acquired from the experiments and in accordance with the results of the Buckingham Pi theorem. A cycle and space averaged Nusselt number correlation is suggested as a function of kinetic Reynolds number for oscillating flows. The suggested correlation is useful in predicting heat transfer from oscillating flows through highly porous and permeable solid media at low actuation frequencies and at low heat fluxes applied in the wall. The validity of the Nusselt numbers acquired by correlation is discussed using experimental Nusselt numbers for the selected kinetic Reynolds number interval. The present investigation has possible applications in moderate sized wicked heat pipes, solid matrix compact heat exchangers compromising of metallic foams, filtration equipment, and steam generators.

  8. Analysis of condensation on a horizontal cylinder with unknown wall temperature and comparison with the Nusselt model of film condensation

    Science.gov (United States)

    Bahrami, Parviz A.

    1996-01-01

    Theoretical analysis and numerical computations are performed to set forth a new model of film condensation on a horizontal cylinder. The model is more general than the well-known Nusselt model of film condensation and is designed to encompass all essential features of the Nusselt model. It is shown that a single parameter, constructed explicitly and without specification of the cylinder wall temperature, determines the degree of departure from the Nusselt model, which assumes a known and uniform wall temperature. It is also known that the Nusselt model is reached for very small, as well as very large, values of this parameter. In both limiting cases the cylinder wall temperature assumes a uniform distribution and the Nusselt model is approached. The maximum deviations between the two models is rather small for cases which are representative of cylinder dimensions, materials and conditions encountered in practice.

  9. Call for Nominations The Nusselt Reynolds Prize Sponsored by Assembly of World Conferences on Experimental Heat Transfer, Fluid Mechanics, and Thermodynamics

    Science.gov (United States)

    Kasagi, Nobuhide

    2000-01-01

    The Nusselt Reynolds Prize has been established by the Assembly of World Conferences to commemorate outstanding contributions by Wilhelm Nusselt and Osborne Reynolds as experimentalists, researchers, educators, and authors. As many as three prizes may be bestowed at every World Conference, one in each of the areas of heat transfer, fluid mechanics, thermodynamics, or any combination of these.

  10. The effect of induced magnetic field and convective boundary condition on MHD stagnation point flow and heat transfer of upper-convected Maxwell fluid in the presence of nanoparticle past a stretching sheet

    Directory of Open Access Journals (Sweden)

    Wubshet Ibrahim

    2016-06-01

    The numerical results are obtained for velocity, temperature, induced magnetic field and concentration profiles as well as skin friction coefficient, the local Nusselt number and Sherwood number. The results indicate that the skin friction coefficient, the local Nusselt number and Sherwood number decrease with an increase in B and M parameters. Moreover, local Sherwood number -ϕ′(0 decreases with an increase in convective parameter Bi, but the local Nusselt number -θ′(0 increases with an increase in Bi. The results are displayed both in graphical and tabular form to illustrate the effect of the governing parameters on the dimensionless velocity, induced magnetic field, temperature and concentration. The numerical results are compared and found to be in good agreement with the previously published results on special cases of the problem.

  11. On Reynolds number dependence of micro-ramp-induced transition

    NARCIS (Netherlands)

    Ye, Q.; Schrijer, F.F.J.; Scarano, F.

    2018-01-01

    The variation of transitional flow features past a micro-ramp is investigated when the Reynolds number is decreased approaching the critical regime. Experiments are conducted in the incompressible flow spanning from supercritical to subcritical roughness-height-based Reynolds number ( , 730, 460

  12. Thermal convection for large Prandtl numbers

    NARCIS (Netherlands)

    Grossmann, Siegfried; Lohse, Detlef

    2001-01-01

    The Rayleigh-Bénard theory by Grossmann and Lohse [J. Fluid Mech. 407, 27 (2000)] is extended towards very large Prandtl numbers Pr. The Nusselt number Nu is found here to be independent of Pr. However, for fixed Rayleigh numbers Ra a maximum in the Nu(Pr) dependence is predicted. We moreover offer

  13. Scaling relations in large-Prandtl-number natural thermal convection

    NARCIS (Netherlands)

    Shishkina, Olga; Emran, Mohammad S.; Grossmann, Siegfried; Lohse, Detlef

    2017-01-01

    In this study, we follow Grossmann and Lohse [Phys. Rev. Lett. 86, 3316 (2001)10.1103/PhysRevLett.86.3316], who derived various scalings regimes for the dependence of the Nusselt number Nu and the Reynolds number Re on the Rayleigh number Ra and the Prandtl number Pr. We focus on theoretical

  14. Number 2 Feibi Recipe Reduces PM2.5-Induced Lung Injury in Rats

    Directory of Open Access Journals (Sweden)

    Zhaoheng Liu

    2018-01-01

    Full Text Available Air pollution is the main cause of respiratory diseases. Fine particulates with the diameter below 2.5 μm can get into the alveoli and then enter the blood circulation through the lung tissue ventilation function and cause multiple systemic diseases especially the respiratory diseases. This study investigated the pathological mechanism of the lungs injury in rats induced by PM2.5 and the effect and mechanism of the Chinese herbal medicine number 2 Feibi Recipe (number 2 FBR on lungs injury. In this experiment, Wistar rats were used. Lungs injury was induced by PM2.5. Number 2 FBR was used to treat the rats. The result showed that number 2 FBR could improve the lung injury in the rats. Meanwhile, it significantly reduced pathological response and inflammatory mediators including interleukin-6 (IL-6, interleukin-13 (IL-13, interleukin-17 (IL17, monocyte chemotactic protein-1 (MCP-1, and transforming growth factor-α (TNF-α and upregulated glutathione peroxidase (GSH-Px in the PM2.5 induced lung injury in the rats. Collectively, number 2 FBR appears to attenuate the lungs injury in rats induced by PM2.5.

  15. Construction of thiostrepton-inducible, high-copy-number expression vectors for use in Streptomyces spp.

    NARCIS (Netherlands)

    Takano, Eriko; White, Janet; Thompson, Charles J.; Bibb, Mervyn J.

    1995-01-01

    A high-copy-number plasmid expression vector (pIJ6021) was constructed that contains a thiostrepton-inducible promoter, PtipA, from Streptomyces lividans 66. The promoter and ribosome-binding site of tipA lie immediately upstream from a multiple cloning site (MCS) which begins with a NdeI site

  16. Some remarks on real numbers induced by first-order spectra

    DEFF Research Database (Denmark)

    Jakobsen, Sune; Simonsen, Jakob Grue

    2016-01-01

    The spectrum of a first-order sentence is the set of natural numbers occurring as the cardinalities of finite models of the sentence. In a recent survey, Durand et al. introduce a new class of real numbers, the spectral reals, induced by spectra and pose two open problems associated to this class...... may occur, and (iv) every right-computable real number between 0 and 1 occurs as the subword entropy of a spectral real. In addition, Durand et al. note that the set of spectral reals is not closed under addition or multiplication. We extend this result by showing that the class of spectral reals...

  17. An increase in the number of admitted patients with exercise-induced rhabdomyolysis.

    Science.gov (United States)

    Aalborg, Christian; Rød-Larsen, Cecilie; Leiro, Ingjerd; Aasebø, Willy

    2016-10-01

    Rhabdomyolysis may lead to serious complications, and treatment is both time-consuming and costly. The condition can be caused by many factors, including intense exercise. The purpose of this study was to investigate whether the number of hospitalisations due to exercise-induced rhabdomyolysis has changed in recent years. We describe the disease course in hospitalised patients, and compare disease course in individuals with exercise-induced rhabdomyolysis and rhabdomyolysis due to other causes. The study is a systematic review of medical records from Akershus University Hospital for the years 2008 and 2011 – 14. All hospitalised patients with diagnostic codes M62.8, M62.9 and T79.6 and creatine kinase levels > 5 000 IU/l were included. The cause of the rhabdomyolysis was recorded in addition to patient characteristics and the results of various laboratory tests. Of 161 patients who were hospitalised with rhabdomyolysis during the study period, 44 cases (27  %) were classified as exercise-induced. In 2008 there were no admissions due to exercise-induced rhabdomyolysis; in 2011 and 2012 there were six and four admissions respectively, while in 2014 there were 22. This gives an estimated incidence of 0.8/100 000 in 2012 and 4.6/100 000 in 2014. Strength-training was the cause of hospitalisation in 35 patients (80  % of the exercise-induced cases). Three patients (7  % of the exercise-induced cases) had transient stage 1 kidney injury, but there were no cases with stage 2 or stage 3 injury. By comparison, 52  % of patients with rhabdomyolysis due to another cause had kidney injury, of which 28  % was stage 2 or 3. The number of persons hospitalised with exercise-induced rhabdomyolysis has increased four-fold from 2011 to 2014, possibly due to changes in exercise habits in the population. None of the patients with exercise-induced rhabdomyolysis had serological signs of kidney injury upon hospital discharge.

  18. PEX11β induces peroxisomal gene expression and alters peroxisome number during early Xenopus laevis development

    Directory of Open Access Journals (Sweden)

    Damjanovski Sashko

    2011-04-01

    Full Text Available Abstract Background Peroxisomes are organelles whose roles in fatty acid metabolism and reactive oxygen species elimination have contributed much attention in understanding their origin and biogenesis. Many studies have shown that de novo peroxisome biogenesis is an important regulatory process, while yeast studies suggest that total peroxisome numbers are in part regulated by proteins such as Pex11, which can facilitate the division of existing peroxisomes. Although de novo biogenesis and divisions are likely important mechanisms, the regulation of peroxisome numbers during embryonic development is poorly understood. Peroxisome number and function are particularly crucial in oviparous animals such as frogs where large embryonic yolk and fatty acid stores must be quickly metabolized, and resulting reactive oxygen species eliminated. Here we elucidate the role of Pex11β in regulating peroxisomal gene expression and number in Xenopus laevis embryogenesis. Results Microinjecting haemagglutinin (HA tagged Pex11β in early embryos resulted in increased RNA levels for peroxisome related genes PMP70 and catalase at developmental stages 10 and 20, versus uninjected embryos. Catalase and PMP70 proteins were found in punctate structures at stage 20 in control embryos, whereas the injection of ectopic HA-Pex11β induced their earlier localization in punctate structures at stage 10. Furthermore, the peroxisomal marker GFP-SKL, which was found localized as peroxisome-like structures at stage 20, was similarly found at stage 10 when co-microinjected with HA-Pex11β. Conclusions Overexpressed Pex11β altered peroxisomal gene levels and induced the early formation of peroxisomes-like structures during development, both of which demonstrate that Pex11β may be a key regulator of peroxisome number in early Xenopus embryos.

  19. Remodeling of the Mandibular Bone Induced by Overdentures Supported by Different Numbers of Implants.

    Science.gov (United States)

    Li, Kai; Xin, Haitao; Zhao, Yanfang; Zhang, Zhiyuan; Wu, Yulu

    2016-05-01

    The objective of this study was to investigate the process of mandibular bone remodeling induced by implant-supported overdentures. computed tomography (CT) images were collected from edentulous patients to reconstruct the geometry of the mandibular bone and overdentures supported by implants. Based on the theory of strain energy density (SED), bone remodeling models were established using the user material subroutine (UMAT) in abaqus. The stress distribution in the mandible and bone density change was investigated to determine the effect of implant number on the remodeling of the mandibular bone. The results indicated that the areas where high Mises stress values were observed were mainly situated around the implants. The stress was concentrated in the distal neck region of the distal-most implants. With an increased number of implants, the biting force applied on the dentures was almost all taken up by implants. The stress and bone density in peri-implant bone increased. When the stress reached the threshold of remodeling, the bone density began to decrease. In the posterior mandible area, the stress was well distributed but increased with decreased implant numbers. Changes in bone density were not observed in this area. The computational results were consistent with the clinical data. The results demonstrate that the risk of bone resorption around the distal-most implants increases with increased numbers of implants and that the occlusal force applied to overdentures should be adjusted to be distributed more in the distal areas of the mandible.

  20. EFFECT OF NIGELLA SATIVA ON NUMBER OF CYSTIC FOLLICLES IN LETROZOLE INDUCED POLYCYSTIC OVARIES IN MICE

    Directory of Open Access Journals (Sweden)

    Noreen Anwar

    2016-06-01

    Full Text Available Objective: To observe the protective effect of Nigella sativa on number of cystic follicles in Letrozole induced polycystic ovaries in mice. Study Design: Laboratory based randomized control trial. Place and Duration of Study: Department of Anatomy, Army Medical College in collaboration with National Institute of Health from Nov 2014 to Nov 2015. Material and Methods: Forty female BALB/c mice were selected and divided in four groups, each having 10 animals. Group A served as control and was given normal diet. Group B was given Letrozole at a dose of 1milligram/kilogram body weight. Group C was treated with Letrozole for eight weeks at a dose of 1milligram/kilogram body weight and Nigella sativa seeds powder at a dose of 10grams/kilogram body weight once daily starting at 22 day and continued up to eight weeks. Group D was treated with Letrozole for eight weeks at a dose of 1milligram/kilogram body weight and Nigella sativa oil at a dose of 4milliliter/kilogram body weight once daily starting at 22 day and continued up to eight weeks. Animals were dissected a day after last dose. Size, shape, color and consistency of ovary was observed. Right ovary was processed, embedded and stained for histological study. Number of cystic follicles were counted and noted. Results: Significant number of cystic follicles was observed in ovaries of animals of group B as compared to group A. While their number decreased significantly in group C and D as compared to group B. Conclusion: Nigella sativa seeds powder and its oil, both have a similar protective effect on histomorphology of ovary of polycystic ovarian syndrome (PCOS in mice by decreasing the number of cystic follicles.

  1. Prandtl number variation on transient forced convection flow in a ...

    African Journals Online (AJOL)

    user

    and average Nusselt number, mean temperature of the fluids (base fluid and nanofluid) and subdomain velocity with the variation of non-dimensional time (τ) ... where the effects of non-uniform particle diameter and temperature on thermal conductivity were shown. Up to now, all the .... is dynamic viscosity and. (. ) (. ) 2. 2. 2.

  2. Number Theoretic Example of Scale-Free Topology Inducing Self-Organized Criticality

    Science.gov (United States)

    Luque, Bartolo; Miramontes, Octavio; Lacasa, Lucas

    2008-10-01

    In this Letter we present a general mechanism by which simple dynamics running on networks become self-organized critical for scale-free topologies. We illustrate this mechanism with a simple arithmetic model of division between integers, the division model. This is the simplest self-organized critical model advanced so far, and in this sense it may help to elucidate the mechanism of self-organization to criticality. Its simplicity allows analytical tractability, characterizing several scaling relations. Furthermore, its mathematical nature brings about interesting connections between statistical physics and number theoretical concepts. We show how this model can be understood as a self-organized stochastic process embedded on a network, where the onset of criticality is induced by the topology.

  3. Glomerular number and function are influenced by spontaneous and induced low birth weight in rats

    DEFF Research Database (Denmark)

    Schreuder, Michiel F; Nyengaard, Jens Randel; Fodor, M

    2005-01-01

    and experimental IUGR, induced by bilateral uterine artery ligation. Design-based stereologic methods were used. Urinary protein excretion was determined as a measure of renal damage. Results showed a decrease of approximately 20% in glomerular number in both groups of IUGR (control 35,400, naturally occurring...... IUGR 30,900, and experimental IUGR 28,000 glomeruli per kidney). Mean glomerular volume was increased in both IUGR groups, which was associated with an increased proteinuria. It is concluded that IUGR leads to a nephron endowment with a compensatory glomerular enlargement. This compensation...... is associated with more proteinuria in the long run. Uterine artery ligation in the pregnant rat is a suitable model to study the effects of IUGR on the kidney....

  4. Telomere dysfunction reduces microglial numbers without fully inducing an aging phenotype

    DEFF Research Database (Denmark)

    Khan, Asif Manzoor; Babcock, Alicia; Saeed, Hamid

    2015-01-01

    The susceptibility of the aging brain to neurodegenerative disease may in part be attributed to cellular aging of the microglial cells that survey it. We investigated the effect of cellular aging induced by telomere shortening on microglia by the use of mice lacking the telomerase RNA component...... distribution and normal expression of CD45 and CD68 and the aging marker, ferritin, but were morphologically distinct from microglia in both adult and old wild-type mice. TERC KO mice also showed increased cellular apoptosis and impaired spatial learning. Our results suggest that individual microglia...... are relatively resistant to telomerase deficiency during steady state conditions, despite an overall reduction in microglial numbers. Furthermore, telomerase deficiency and aging may provide disparate cues leading to distinct changes in microglial morphology and phenotype....

  5. Changes in the numbers of ribbon synapses and expression of RIBEYE in salicylate-induced tinnitus.

    Science.gov (United States)

    Zhang, Feng-Ying; Xue, Yi-Xue; Liu, Wen-Jing; Yao, Yi-Long; Ma, Jun; Chen, Lin; Shang, Xiu-Li

    2014-01-01

    This study was performed to explore the mechanism underlying tinnitus by investigating the changes in the synaptic ribbons and RIBEYE expression in cochlear inner hair cells in salicylate-induced tinnitus. C57BL/6J mice were injected with salicylate (350 mg/kg) for 10 days and grouped. Behavioral procedures were performed to assess whether the animals experienced tinnitus. The specific presynaptic RIBEYE protein and non-specific postsynaptic glutamate receptor 2&3 protein in basilar membrane samples were examined by immunofluorescent labeling. RT-PCR and Western blot assays were used to examine RIBEYE expression. Serial sections were used to build three-dimensional models using 3ds MAX software to evaluate the changes in the synaptic ribbons. The administration of salicylate increased false positives in the behavioral procedure from 3 d to 10 d. The membrane profiles of inner hair cells in all mice were intact. The number of synaptic ribbons in the salicylate group increased on the 7(th) d and decreased on the 9(th) and 10(th) d. mRNA and protein expression of RIBEYE were initially up-regulated and later down-regulated by injecting salicylate for 10 consecutive days. This change in the ribbon synapses of cochlear inner hair cells in salicylate-induced mice might serve as a compensatory mechanism in the early stages of ototoxicity and contribute to tinnitus later. The alteration of RIBEYE expression could be responsible for the changes in the morphology of ribbon synapses and for salicylate-induced tinnitus. © 2014 S. Karger AG, Basel.

  6. Numerical investigation on flow-induced vibration of a triangular cylinder at a low Reynolds number

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Huakun; Zhao, Dongliang; Yang, Wenyu; Yu, Guoliang, E-mail: yugl@sjtu.edu.cn [State Key Laboratory of Ocean Engineering, School of Naval Architecture, Ocean and Civil Engineering, Shanghai Jiao Tong University, Shanghai, People’s Republic of China (China)

    2015-02-01

    Flow-induced vibration (FIV) of a triangular cylinder is numerically investigated at a Reynolds number of Re = 100. The four-step fractional finite element method is employed to solve the two-dimensional (2D) incompressible Navier–Stokes equations. The cylinder is endowed with a two-degree-of-freedom motion with the reduced mass ratio of M{sub r} = 2. Three typical flow incidence angles, α = 0°, 30° and 60°, are examined to identify the effect of incidence angle on the vibration characteristics of the cylinder. For each α, computations are conducted in a wide range of reduced velocities 2 U{sub r} ≤ 18. The numerical results show that at α = 0° and 30°, the responses of the cylinder are dominated by vortex-induced vibration which resembles that of a circular cylinder. At α = 0°, the peak amplitude of transverse vibration is the smallest among the three investigated α, and most of the cylinder motions exhibit a regular figure-eight trajectory. Some single-loop trajectories are observed at α = 30°, where the vibration frequency in the in-line direction is always identical to that in the transverse direction. At α = 60°, the triangular cylinder undergoes a typical transverse galloping with large amplitude and low frequency, and the vibration trajectories appear to be regular or irregular figure-eight patterns, which are strongly affected by the reduced velocity. (paper)

  7. Effects of the number of inducer blades on the anti-cavitation characteristics and external performance of a centrifugal pump

    Energy Technology Data Exchange (ETDEWEB)

    Guo, XiaoMei; Shi, GaoPing [Zhejiang University of Water Resources and Electric Power, Hangzhou (China); Zhu, ZuChao; Cui, BaoLing [Zhejiang Sci-Tech University, Hangzhou (China)

    2016-07-15

    Installing an inducer upstream of the main impeller is an effective approach for improving the anti-cavitation performance of a high speed centrifugal pump. For a high-speed centrifugal pump with an inducer, the number of inducer blades can affect its internal flow and external performance. We studied the manner in which the number of inducer blades can affect the anti-cavitation characteristics and external performance of a centrifugal pump. We first use the Rayleigh-Plesset equation and the mixture model to simulate the vapor liquid flow in a centrifugal pump with an inducer, and then predict its external performance. Finally, we tested the external performance of a centrifugal pump with 2-, 3- and 4-bladed inducers, respectively. The results show that the simulations of external performance in a centrifugal pump are in accordance with our experiments. Based on this, we obtained vapor volume fraction distributions for the inducer, the impeller, and in the corresponding whole flow parts. We discovered that the vapor volume fraction of a centrifugal pump with a 3- bladed inducer is less than that of a centrifugal pump with 2- or 4-bladed inducers, which means that a centrifugal pump with a 3-bladed inducer has a better external and anti-cavitation performance.

  8. Vortex-Induced Vibration Tests of a Marine Growth Wrapped Cylinder at Subcritical Reynolds Number

    Directory of Open Access Journals (Sweden)

    Kurian V. J.

    2017-01-01

    Full Text Available Vortex Induced Vibrations (VIV may cause great damage to deep water risers. Estimation of accurate hydrodynamic coefficients and response amplitudes for fouled tubular cylinders subjected to VIVs is a complex task. This paper presents the results of an extensive experimental investigation on in-line and cross-flow forces acting on cylinders wrapped with marine growth, subjected to current at Subcritical Reynolds Number. The drag and lift force coefficients have been determined through the use of the Fast Fourier Analysis methods. The different tests were conducted in the offshore engineering laboratory at Universiti Teknologi PETRONAS (UTP, Malaysia. In this study, a cylinder with outer diameter Do = 27 mm, fixed at top as cantilever beam was used. The in-line and cross-flow forces were measured using VIV Force Totaller (VIVFT. VIVFT is a two degree of freedom (2DOF forces sensor developed by UTP to measure the VIV forces. The tests were conducted for current velocity varied between 0.118 to 0.59 m/s. The test results suggest that the cylinder wrapped with marine growth has shown an overall increase in drag and inertia coefficients as well as on response amplitudes.

  9. Wood Ash Induced pH Changes Strongly Affect Soil Bacterial Numbers and Community Composition.

    Science.gov (United States)

    Bang-Andreasen, Toke; Nielsen, Jeppe T; Voriskova, Jana; Heise, Janine; Rønn, Regin; Kjøller, Rasmus; Hansen, Hans C B; Jacobsen, Carsten S

    2017-01-01

    Recirculation of wood ash from energy production to forest soil improves the sustainability of this energy production form as recycled wood ash contains nutrients that otherwise would be lost at harvest. In addition, wood-ash is beneficial to many soils due to its inherent acid-neutralizing capabilities. However, wood ash has several ecosystem-perturbing effects like increased soil pH and pore water electrical conductivity both known to strongly impact soil bacterial numbers and community composition. Studies investigating soil bacterial community responses to wood ash application remain sparse and the available results are ambiguous and remain at a general taxonomic level. Here we investigate the response of bacterial communities in a spruce forest soil to wood ash addition corresponding to 0, 5, 22, and 167 t wood ash ha -1 . We used culture-based enumerations of general bacteria, Pseudomonas and sporeforming bacteria combined with 16S rRNA gene amplicon sequencing to valuate soil bacterial responses to wood ash application. Results showed that wood ash addition strongly increased soil pH and electrical conductivity. Soil pH increased from acidic through neutral at 22 t ha -1 to alkaline at 167 t ha -1 . Bacterial numbers significantly increased up to a wood ash dose of 22 t ha -1 followed by significant decrease at 167 t ha -1 wood ash. The soil bacterial community composition changed after wood ash application with copiotrophic bacteria responding positively up to a wood ash dose of 22 t ha -1 while the adverse effect was seen for oligotrophic bacteria. Marked changes in bacterial community composition occurred at a wood ash dose of 167 t ha -1 with a single alkaliphilic genus dominating. Additionally, spore-formers became abundant at an ash dose of 167 t ha -1 whereas this was not the case at lower ash doses. Lastly, bacterial richness and diversity strongly decreased with increasing amount of wood ash applied. All of the observed bacterial responses can be

  10. DNA copy number analysis from mice with radiation-induced acute myeloid leukemia

    Data.gov (United States)

    National Aeronautics and Space Administration — Certain mouse strains such as CBA C3H and RFM have high incidence of radiation-induced acute myeloid leukemia (AML). The data in this series wer generated by using...

  11. Effects of Number of Repetitions and Number of Hours of Shaping Practice during Constraint-Induced Movement Therapy: A Randomized Controlled Trial

    Directory of Open Access Journals (Sweden)

    Auwal Abdullahi

    2018-01-01

    Full Text Available Background. Constraint-induced movement therapy (CIMT is effective in improving motor outcomes after stroke. However, its existing protocols are resource-intensive and difficult to implement. The aim of this study is to design an easier CIMT protocol using number of repetitions of shaping practice. Method. The study design was randomized controlled trial. Participants within 4 weeks after stroke were recruited at Murtala Muhammad Specialist Hospital. They were randomly assigned to groups A, B, C, and D. Group A received 3 hours of traditional therapy. Groups B, C, and D received modified CIMT consisting of 3 hours of shaping practice per session, 300 repetitions of shaping practice in 3 sessions, and 600 repetitions of shaping practice in 3 sessions per day, respectively, and constraint for 90% of the waking hours. All treatment protocols were administered 5 times per week for 4 weeks. The primary outcome was measured using upper limb Fugl-Meyer assessment, while the secondary outcome was measured using motor activity log, Wolf Motor Function Test, and upper limb self-efficacy test at baseline, 2 weeks, and 4 weeks after intervention. Result. There were 48 participants 4 weeks after intervention. The result showed that there was no significant difference between groups at baseline (p>0.05. Within-group improvements attained minimal clinically important difference (MCID in modified CIMT and 300 repetitions and 600 repetitions groups. Conclusion. Number of repetitions of shaping practice significantly improved motor function, real-world arm use, and upper limb self-efficacy after stroke. Therefore, it seems to be a simple alternative for the use of number of hours. Trial Registration. This trial is registered with Pan African Clinical Trial Registry (registration number: PACTR201610001828172 (date of registration: 21/10/2016.

  12. Sphaleron-induced baryon-number nonconservation and a constraint on Majorana neutrino masses

    International Nuclear Information System (INIS)

    Fukugita, M.; Yanagida, T.

    1990-01-01

    We point out that the baryon-number asymmetry in the Universe is erased by the sphaleron effect just below the electroweak phase transition irrespective of the primordial baryon- and lepton-number asymmetry, if there exists a Majorana-type interaction. The requirement to avoid this happening leads to the condition that m ν (Majorana) <50 keV for all species of neutrinos, regardless of whether or not neutrinos are stable

  13. Long-term abacus training induces automatic processing of abacus numbers in children.

    Science.gov (United States)

    Du, Fenglei; Yao, Yuan; Zhang, Qiong; Chen, Feiyan

    2014-01-01

    Abacus-based mental calculation (AMC) is a unique strategy for arithmetic that is based on the mental abacus. AMC experts can solve calculation problems with extraordinarily fast speed and high accuracy. Previous studies have demonstrated that abacus experts showed superior performance and special neural correlates during numerical tasks. However, most of those studies focused on the perception and cognition of Arabic numbers. It remains unclear how the abacus numbers were perceived. By applying a similar enumeration Stroop task, in which participants are presented with a visual display containing two abacus numbers and asked to compare the numerosity of beads that consisted of the abacus number, in the present study we investigated the automatic processing of the numerical value of abacus numbers in abacus-trained children. The results demonstrated a significant congruity effect in the numerosity comparison task for abacus-trained children, in both reaction time and error rate analysis. These results suggested that the numerical value of abacus numbers was perceived automatically by the abacus-trained children after long-term training.

  14. Family number non-conservation induced by the supersymmetric mixing of scalar leptons

    Energy Technology Data Exchange (ETDEWEB)

    Levine, M.J.S.

    1987-08-01

    The most egregious aspect of (N = 1) supersymmetric theories is that each particle state is accompanied by a 'super-partner', a state with identical quantum numbers save that it differs in spin by one half unit. For the leptons these are scalars and are called ''sleptons'', or scalar leptons. These consist of the charged sleptons (selectron, smuon, stau) and the scalar neutrinos ('sneutrinos'). We examine a model of supersymmetry with soft breaking terms in the electroweak sector. Explicit mixing among the scalar leptons results in a number of effects, principally non-conservation of lepton family number. Comparison with experiment permits us to place constraints upon the model. 49 refs., 12 figs.

  15. Analyzing logistic map pseudorandom number generators for periodicity induced by finite precision floating-point representation

    International Nuclear Information System (INIS)

    Persohn, K.J.; Povinelli, R.J.

    2012-01-01

    Highlights: ► A chaotic pseudorandom number generator (C-PRNG) poorly explores the key space. ► A C-PRNG is finite and periodic when implemented on a finite precision computer. ► We present a method to determine the period lengths of a C-PRNG. - Abstract: Because of the mixing and aperiodic properties of chaotic maps, such maps have been used as the basis for pseudorandom number generators (PRNGs). However, when implemented on a finite precision computer, chaotic maps have finite and periodic orbits. This manuscript explores the consequences finite precision has on the periodicity of a PRNG based on the logistic map. A comparison is made with conventional methods of generating pseudorandom numbers. The approach used to determine the number, delay, and period of the orbits of the logistic map at varying degrees of precision (3 to 23 bits) is described in detail, including the use of the Condor high-throughput computing environment to parallelize independent tasks of analyzing a large initial seed space. Results demonstrate that in terms of pathological seeds and effective bit length, a PRNG based on the logistic map performs exponentially worse than conventional PRNGs.

  16. Projectile atomic-number effect on ion-induced fragmentation and ionization of fullerenes

    NARCIS (Netherlands)

    Hadjar, O; Hoekstra, R; Morgenstern, R; Schlatholter, T

    The delocalized pi electrons of a C-60 cluster can be well described as an electron gas. Electronic friction experienced by a multicharged ion colliding with a fullerene might then be modeled in terms of the electronic stopping power. We investigated such collisions for projectile atomic numbers Z

  17. Nonparametric testing for DNA copy number induced differential mRNA gene expression

    NARCIS (Netherlands)

    van Wieringen, W.N.; van de Wiel, M.A.

    2009-01-01

    The central dogma of molecular biology relates DNA with mRNA. Array CGH measures DNA copy number and gene expression microarrays measure the amount of mRNA. Methods that integrate data from these two platforms may uncover meaningful biological relationships that further our understanding of cancer.

  18. Wood Ash Induced pH Changes Strongly Affect Soil Bacterial Numbers and Community Composition

    DEFF Research Database (Denmark)

    Bang-Andreasen, Toke; Nielsen, Jeppe T.; Voriskova, Jana

    2017-01-01

    -neutralizing capabilities. However, wood ash has several ecosystem-perturbing effects like increased soil pH and pore water electrical conductivity both known to strongly impact soil bacterial numbers and community composition. Studies investigating soil bacterial community responses to wood ash application remain sparse...

  19. Fetal cyclophosphamide exposure induces testicular cancer and reduced spermatogenesis and ovarian follicle numbers in mice.

    Directory of Open Access Journals (Sweden)

    Paul B Comish

    Full Text Available Exposure to radiation during fetal development induces testicular germ cell tumors (TGCT and reduces spermatogenesis in mice. However, whether DNA damaging chemotherapeutic agents elicit these effects in mice remains unclear. Among such agents, cyclophosphamide (CP is currently used to treat breast cancer in pregnant women, and the effects of fetal exposure to this drug manifested in the offspring must be better understood to offer such patients suitable counseling. The present study was designed to determine whether fetal exposure to CP induces testicular cancer and/or gonadal toxicity in 129 and in 129.MOLF congenic (L1 mice. Exposure to CP on embryonic days 10.5 and 11.5 dramatically increased TGCT incidence to 28% in offspring of 129 mice (control value, 2% and to 80% in the male offspring of L1 (control value 33%. These increases are similar to those observed in both lines of mice by radiation. In utero exposure to CP also significantly reduced testis weights at 4 weeks of age to ∼ 70% of control and induced atrophic seminiferous tubules in ∼ 30% of the testes. When the in utero CP-exposed 129 mice reached adulthood, there were significant reductions in testicular and epididymal sperm counts to 62% and 70%, respectively, of controls. In female offspring, CP caused the loss of 77% of primordial follicles and increased follicle growth activation. The results indicate that i DNA damage is a common mechanism leading to induction of testicular cancer, ii increased induction of testis cancer by external agents is proportional to the spontaneous incidence due to inherent genetic susceptibility, and iii children exposed to radiation or DNA damaging chemotherapeutic agents in utero may have increased risks of developing testis cancer and having reduced spermatogenic potential or diminished reproductive lifespan.

  20. Density maximum effect on Soret-induced natural convection in a square porous cavity

    Science.gov (United States)

    Alloui, Z.; Robillard, L.; Vasseur, P.

    2010-10-01

    This paper reports a numerical study on the effect of density maximum on Soret-induced convection in a square porous cavity. Dirichlet boundary conditions for temperature are applied to the vertical walls of the enclosure, while the two horizontal ones are assumed impermeable and insulated. The non-dimensional equations for momentum, energy and concentration are solved by a finite volume method with power-law scheme for convection and diffusion. A parametric study is undertaken as a function of the main dimensionless group characterizing the problem, namely the thermal Rayleigh number, RT, the solutal Rayleigh number, RS, the Lewis number Le and an extremum parameter γ, which quantifies the effect of the nonlinear equation of state. The results are presented in the form of streamlines, isotherms and isoconcentration lines for various values of the governing parameters. Comprehensive Nusselt number data are presented as functions of the governing parameters mentioned above.

  1. Spectroscopic Temperature and Number Density of Nitric Oxide in Laser-Induced Plasma

    Science.gov (United States)

    Fleischmann, Josef P.; Swafford, Lauren D.; Witte, Michael J.; Surmick, David M.; Woods, Alexander C.; Behery, Sultan A.; Parigger, Christian G.; Hornkohl, James O.

    2014-03-01

    We report measurements of nitric oxide emission spectra subsequent to infra-red Nd:YAG laser-induced breakdown in air. Plasma is generated by focusing 160 mJ energy per pulse, 13 ns pulse-width, laser radiation at a wavelength of 1064 nm. The NO emissions are recorded for time delays of 25, 50, and 75 μs after plasma generation, utilizing a 0.64 meter Czerny-Turner type spectrometer with a 3600 grooves/mm grating, and an intensified linear diode array. The analysis utilizes accurate line strengths for selected bands in the ultraviolet region of 205 to 300 nm. Temperatures on the order of 6000 to 7000 Kelvin are inferred from the emission spectra. Comparisons are included with previous experimental studies in 1:1 mixture of N2:O2, where we deduced temperature and species densities using plasma predictions for various conditions and a so-called non-equilibrium air radiation code. The current work elaborates on details of two specific NO bands to evaluate as well accuracy of our line strength data. While the presented spectra, recorded in laser-induced plasma in air, are due to recombination processes following optical breakdown, results of our work on diatomic nitric oxide emissions are expected to be also applicable in chemical physics investigations of combustion.

  2. HDAC inhibitors induce transcriptional repression of high copy number genes in breast cancer through elongation blockade.

    Science.gov (United States)

    Kim, Y J; Greer, C B; Cecchini, K R; Harris, L N; Tuck, D P; Kim, T H

    2013-06-06

    Treatment with histone deacetylase inhibitors (HDACI) results in potent cytotoxicity of a variety of cancer cell types, and these drugs are used clinically to treat hematological tumors. They are known to repress the transcription of ERBB2 and many other oncogenes, but little is known about this mechanism. Using global run-on sequencing (GRO-seq) to measure nascent transcription, we find that HDACI cause transcriptional repression by blocking RNA polymerase II elongation. Our data show that HDACI preferentially repress the transcription of highly expressed genes as well as high copy number genes in HER2+ breast cancer genomes. In contrast, genes that are activated by HDACI are moderately expressed. We analyzed gene copy number in combination with microarray and GRO-seq analysis of expression level, in normal and breast cancer cells to show that high copy number genes are more likely to be repressed by HDACI than non-amplified genes. The inhibition of transcription of amplified oncogenes, which promote survival and proliferation of cancer cells, might explain the cancer-specific lethality of HDACI, and may represent a general therapeutic strategy for cancer.

  3. Large-eddy simulation of the high-Reynolds-number flow through a high-aspect-ratio cooling duct

    NARCIS (Netherlands)

    Kaller, Thomas; Pasquariello, Vito; Hickel, S.; Adams, Nikolaus A.

    2017-01-01

    We present well-resolved large-eddy-simulations (LES) of a straight, high-aspect-ratio cooling duct (HARCD) at a bulk Reynolds number of Re = 110 • 103 and an average Nusselt number of Nu = 371. The geometry and boundary conditions have been defined together with Rochlitz et al.

  4. Wood ash induced pH changes strongly affect soil bacterial numbers and community composition

    DEFF Research Database (Denmark)

    Bang-Andreasen, Toke; Nielsen, Jeppe T.; Voriskova, Jana

    2017-01-01

    -neutralizing capabilities. However, wood ash has several ecosystem-perturbing effects like increased soil pH and pore water electrical conductivity both known to strongly impact soil bacterial numbers and community composition. Studies investigating soil bacterial community responses to wood ash application remain sparse...... and the available results are ambiguous and remain at a general taxonomic level. Here we investigate the response of bacterial communities in a spruce forest soil to wood ash addition corresponding to 0, 5, 22, and 167 t wood ash ha(-1). We used culture-based enumerations of general bacteria, Pseudomonas......Recirculation of wood ash from energy production to forest soil improves the sustainability of this energy production form as recycled wood ash contains nutrients that otherwise would be lost at harvest. In addition, wood-ash is beneficial to many soils due to its inherent acid...

  5. Effect of transgene number of spontaneous and radiation-induced micronuclei in lacl transgenic mice

    International Nuclear Information System (INIS)

    O'Loughlin, K.G.; Hamer, J.D.; Winegar, R.A.; Mirsalis, J.C.; Short, J.M.

    1994-01-01

    Lacl transgenic mice are widely used for the measurement of mutations in specific target issues. The lacl transgene is present in mice as 40 tandem repeats; this sequence is homozygous (contained in both copies of chromosome 5) in C57Bl/6 mice, and is hemizygous in B6C3F1 mice. Previous reports have indicated that tandem repeats can produce chromosome instability, fragile sites, and other effects. To determine whether the presence of the transgene effects micronucleus induction we compared the response of nontransgenic (NTR) to hemizygous (HEMI) transgenic B6C3F1 mice and to hemizygous and homozygous (HOMO) transgenic C57Bl/6 mice. Five mice/group were irradiated with 500 cGy from a 137 Cs source. Bone marrow was harvested 24 hr after treatment and 2000 polychromatic erythrocytes (PCE) were analyzed per animal. The presence or absence of the lacl transgene had no effect in unirradiated mice on the percent of micronucleated PCE (MN) or on the ratio of PCE to total red blood cells for either strain: B6C3F1 mice had MN frequencies of 0.26% and 0.20% for NTR and HEMI mice, respectively; C57Bl/6 mice had MN frequencies of 0.34%, 0.32%, and 0.38% for NTR, HEMI, and HOMO mice, respectively. Radiation-induced micronucleus frequencies were significantly higher in HEMI lacl B6C3F1 mice (2.85%) than in NTR litter mates (1.59%); the converse was true in C57Bl/6 mice: NTR were 2.45%, HEMI were 1.25%, HOMO were 1.65%. These data suggest that the lacl transgene does not cause chromosome instability as measured by spontaneous micronucleus levels. However, the response of these transgenic mice to a variety of clastogenic agents needs to be investigated before they are integrated into standard in vivo assays for chromosome damage

  6. Influence of Housing System and Number of Transported Animals on Transport-induced Mortality in Slaughter Pigs

    Directory of Open Access Journals (Sweden)

    Eva Voslářová

    2010-01-01

    Full Text Available The study monitored the effect of the housing system and the number of animals transported together on transport-induced mortality of slaughter pigs in the Czech Republic in the period from 2004 to 2008. Concerning the type of housing during the fattening, the lowest mortality rate during the subsequent transport to slaughter houses was detected among pigs fattened on solid floor (0.047% and on deep bedding (0.084%. The highest mortality during transport was detected among pigs fattened on fully or partially slatted floor (0.139%, a significant difference (p p < 0.01 compared to the load sizes of up to 40 animals.

  7. Topology of a dissipative spin: Dynamical Chern number, bath-induced nonadiabaticity, and a quantum dynamo effect

    Science.gov (United States)

    Henriet, Loïc; Sclocchi, Antonio; Orth, Peter P.; Le Hur, Karyn

    2017-02-01

    We analyze the topological deformations of the ground state manifold of a quantum spin-1/2 in a magnetic field H =H (sinθ cosϕ ,sinθ sinϕ ,cosθ ) induced by a coupling to an ohmic quantum dissipative environment at zero temperature. From Bethe ansatz results and a variational approach, we confirm that the Chern number associated with the geometry of the reduced spin ground state manifold is preserved in the delocalized phase for α <1 . We report a divergence of the Berry curvature at αc=1 for magnetic fields aligned along the equator θ =π /2 . This divergence is caused by the complete quenching of the transverse magnetic field by the bath associated with a gap closing that occurs at the localization Kosterlitz-Thouless quantum phase transition in this model. Recent experiments in quantum circuits have engineered nonequilibrium protocols to access topological properties from a measurement of a dynamical Chern number defined via the out-of-equilibrium spin expectation values. Applying a numerically exact stochastic Schrödinger approach we find that, for a fixed field sweep velocity θ (t )=v t , the bath induces a crossover from (quasi)adiabatic to nonadiabatic dynamical behavior when the spin bath coupling α increases. We also investigate the particular regime H /ωc≪v /H ≪1 with large bath cutoff frequency ωc, where the dynamical Chern number vanishes already at α =1 /2 . In this regime, the mapping to an interacting resonance level model enables us to analytically describe the behavior of the dynamical Chern number in the vicinity of α =1 /2 . We further provide an intuitive physical explanation of the bath-induced breakdown of adiabaticity in analogy to the Faraday effect in electromagnetism. We demonstrate that the driving of the spin leads to the production of a large number of bosonic excitations in the bath, which strongly affect the spin dynamics. Finally, we quantify the spin-bath entanglement and formulate an analogy with an effective

  8. A microhomology-mediated break-induced replication model for the origin of human copy number variation.

    Directory of Open Access Journals (Sweden)

    P J Hastings

    2009-01-01

    Full Text Available Chromosome structural changes with nonrecurrent endpoints associated with genomic disorders offer windows into the mechanism of origin of copy number variation (CNV. A recent report of nonrecurrent duplications associated with Pelizaeus-Merzbacher disease identified three distinctive characteristics. First, the majority of events can be seen to be complex, showing discontinuous duplications mixed with deletions, inverted duplications, and triplications. Second, junctions at endpoints show microhomology of 2-5 base pairs (bp. Third, endpoints occur near pre-existing low copy repeats (LCRs. Using these observations and evidence from DNA repair in other organisms, we derive a model of microhomology-mediated break-induced replication (MMBIR for the origin of CNV and, ultimately, of LCRs. We propose that breakage of replication forks in stressed cells that are deficient in homologous recombination induces an aberrant repair process with features of break-induced replication (BIR. Under these circumstances, single-strand 3' tails from broken replication forks will anneal with microhomology on any single-stranded DNA nearby, priming low-processivity polymerization with multiple template switches generating complex rearrangements, and eventual re-establishment of processive replication.

  9. Stress-induced oxytocin release and oxytocin cell number and size in prepubertal and adult male and female rats.

    Science.gov (United States)

    Minhas, Sumeet; Liu, Clarissa; Galdamez, Josselyn; So, Veronica M; Romeo, Russell D

    2016-08-01

    Studies indicate that adolescent exposure to stress is a potent environmental factor that contributes to psychological and physiological disorders, though the mechanisms that mediate these dysfunctions are not well understood. Periadolescent animals display greater stress-induced hypothalamic-pituitary-adrenal (HPA) axis responses than adults, which may contribute to these vulnerabilities. In addition to the HPA axis, the hypothalamo-neurohypophyseal tract (HNT) is also activated in response to stress. In adults, stress activates this system resulting in secretion of oxytocin from neurons in the supraoptic (SON) and paraventricular (PVN) nuclei. However, it is currently unknown whether a similar or different response occurs in prepubertal animals. Given the influence of these hormones on a variety of emotional behaviors and physiological systems known to change as an animal transitions into adulthood, we investigated stress-induced HPA and HNT hormonal responses before and after stress, as well as the number and size of oxytocin-containing cells in the SON and PVN of prepubertal (30d) and adult (70d) male and female rats. Though we found the well-established protracted adrenocorticotropic hormone and corticosterone response in prepubertal males and females, only adult males and prepubertal females showed a significant stress-induced increase in plasma oxytocin levels. Moreover, though we found no pubertal changes in the number of oxytocin cells, we did find a pubertal-related increase in oxytocin somal size in both the SON and PVN of males and females. Taken together, these data indicate that neuroendocrine systems can show different patterns of stress reactivity before and after adolescent development and that these responses can be further modified by sex. Given the impact of these hormones on a variety of systems, it will be imperative to further explore these changes in hormonal stress reactivity and their role in adolescent health. Copyright © 2016 Elsevier

  10. Experimental validation of the design method to prevent flow-induced vibration in high Reynolds-number

    International Nuclear Information System (INIS)

    Sakai, Takaaki; Yamaguchi, Akira; Morisita, Masaki; Iwata, Koji

    1998-08-01

    The incident of sodium leakage from a main pipe of the secondary heat transport system of Monju fast breeder reactor was caused by the failure of a thermometer well. 'Flow-induced vibration design guide for thermometer wells' (express as 'design guide') was proposed by PNC Working Group to prevent the same cause of the sodium leak incident in future. On this report, applicability of the 'design guide' was estimated to plant conditions in high Reynolds-number(approximately 3x10 5 ∼ 3x10 6 ) involving the supercritical region, by measured data on a vortex synchronized vibration and a turbulence induced vibration. Experiments were performed for cylindrical and taper shaped types of test pieces. As results, reduced velocity (Vr) at onsets of the inline synchronized vibration were evaluated to be grater than 1.0 in the range of experimental conditions. Fluctuating drag and lift coefficients, which were evaluated from power spectrum of turbulence for Vr < 1.0 condition, were 0.01 ∼ 0.05 for drag direction and 0.04 ∼ 0.13 for lift direction. The fluctuating drag and lift coefficients used in the 'design guide' were estimated to be conservative by comparison with these data. Correlation lengths for a cylinder and a taper shaped one in the high Reynolds-number region were estimated to be 1.6 times of the diameter(D) in the maximum case. The measured value of correlation length is enough smaller than the 'design guide' value of 3.0D. Displacement amplitudes of test pieces for Vr < 1.0 conditions were enough smaller (fives times) than calculated values based on the 'design guide'. Consequently, the applicability of the design guide' was confirmed in the range of experiments involving the super critical Reynolds-number region. (author)

  11. Association between genome-wide copy number variation and arsenic-induced skin lesions: a prospective study.

    Science.gov (United States)

    Kibriya, Muhammad G; Jasmine, Farzana; Parvez, Faruque; Argos, Maria; Roy, Shantanu; Paul-Brutus, Rachelle; Islam, Tariqul; Ahmed, Alauddin; Rakibuz-Zaman, Muhammad; Shinkle, Justin; Slavkovich, Vesna; Graziano, Joseph H; Ahsan, Habibul

    2017-07-18

    Exposure to arsenic in drinking water is a global health problem and arsenic-induced skin lesions are hallmark of chronic arsenic toxicity. We and others have reported germline genetic variations as risk factors for such skin lesions. The role of copy number variation (CNV) in the germline DNA in this regard is unknown. From a large prospectively followed-up cohort, exposed to arsenic, we randomly selected 2171 subjects without arsenic-induced skin lesions at enrollment and genotyped their whole blood DNA samples on Illumina Cyto12v2.1 SNP chips to generate DNA copy number. Participants were followed up every 2 years for a total of 8 years, especially for the development of skin lesions. In Cox regression models, each CNV segment was used as a predictor, accounting for other potential covariates, for incidence of skin lesions. The presence of genomic deletion(s) in a number of genes (OR5J2, GOLGA6L7P, APBA2, GALNTL5, VN1R31P, PHKG1P2, SGCZ, ZNF658) and lincRNA genes (RP11-76I14.1, CTC-535 M15.2, RP11-73B2.2) were associated with higher risk [HR between 1.67 (CI 1.3-2.1) and 2.15 (CI 1.5-2.9) for different CNVs] for development of skin lesions independent of gender, age, and arsenic exposure. Some deletions had stronger effect in a specific gender (ZNF658 in males, SGCZ in females) and some had stronger effect in higher arsenic exposure (lincRNA CTD-3179P9.1) suggesting a possible gene-environment interaction. This first genome-wide CNV study in a prospectively followed-up large cohort, exposed to arsenic, suggests that DNA deletion in several genes and lincRNA genes may predispose an individual to a higher risk of development of arsenic-induced skin lesions.

  12. The effect of the number of condensed phases modeled on aerosol behavior during an induced steam generator tube rupture sequence

    International Nuclear Information System (INIS)

    Bixler, N.E.; Schaperow, J.H.

    1998-06-01

    VICTORIA is a mechanistic computer code designed to analyze fission product behavior within a nuclear reactor coolant system (RCS) during a severe accident. It provides detailed predictions of the release of radioactive and nonradioactive materials from the reactor core and transport and deposition of these materials within the RCS. A recently completed independent peer review of VICTORIA, while confirming the overall adequacy of the code, recommended a number of modeling improvements. One of these recommendations, to model three rather than a single condensed phase, is the focus of the work reported here. The recommendation has been implemented as an option so that either a single or three condensed phases can be treated. Both options have been employed in the study of fission product behavior during an induced steam generator tube rupture sequence. Differences in deposition patterns and mechanisms predicted using these two options are discussed

  13. B cell depletion reduces the number of autoreactive T helper cells and prevents glucose-6-phosphate isomerase-induced arthritis.

    Directory of Open Access Journals (Sweden)

    Oliver Frey

    Full Text Available The therapeutic benefit of B cell depletion in patients with rheumatoid arthritis has provided proof of concept that B cells are relevant for the pathogenesis of arthritis. It remains unknown which B cell effector functions contribute to the induction or chronification of arthritis. We studied the clinical and immunological effects of B cell depletion in glucose-6-phosphate isomerase-induced arthritis. We targeted CD22 to deplete B cells. Mice were depleted of B cells before or after immunization with glucose-6-phosphate isomerase (G6PI. The clinical and histological effects were studied. G6PI-specific antibody responses were measured by ELISA. G6PI-specific T helper (Th cell responses were assayed by polychromatic flow cytometry. B cell depletion prior to G6PI-immunization prevented arthritis. B cell depletion after immunization ameliorated arthritis, whereas B cell depletion in arthritic mice was ineffective. Transfer of antibodies from arthritic mice into B cell depleted recipients did not reconstitute arthritis. B cell depleted mice harbored much fewer G6PI-specific Th cells than control animals. B cell depletion prevents but does not cure G6PI-induced arthritis. Arthritis prevention upon B cell depletion is associated with a drastic reduction in the number of G6PI-specific effector Th cells.

  14. Mouse Lymphoblastic Leukemias Induced by Aberrant Prdm14 Expression Demonstrate Widespread Copy Number Alterations Also Found in Human ALL

    Energy Technology Data Exchange (ETDEWEB)

    Simko, Stephen J., E-mail: simko@bcm.edu [Baylor College of Medicine, Department of Pediatrics, Texas Children’s Cancer and Hematology Centers, One Baylor Plaza, Houston, TX 77030 (United States); Voicu, Horatiu [Baylor College of Medicine, Dan L. Duncan Cancer Center, One Baylor Plaza, Houston, TX 77030 (United States); Carofino, Brandi L. [Baylor College of Medicine, Department of Molecular and Human Genetics, One Baylor Plaza, Houston, TX 77030 (United States); Baylor College of Medicine, Interdepartmental Program in Translational Biology and Molecular Medicine, One Baylor Plaza, Houston, TX 77030 (United States); Justice, Monica J. [Baylor College of Medicine, Dan L. Duncan Cancer Center, One Baylor Plaza, Houston, TX 77030 (United States); Baylor College of Medicine, Department of Molecular and Human Genetics, One Baylor Plaza, Houston, TX 77030 (United States)

    2012-10-18

    Aberrant expression and activation of oncogenes in somatic cells has been associated with cancer initiation. Required for reacquisition of pluripotency in the developing germ cell, PRDM14 initiates lymphoblastic leukemia when misexpressed in murine bone marrow. Activation of pluripotency in somatic cells can lead to aneuploidy and copy number alterations during iPS cell generation, and we hypothesized that PRDM14-induced lymphoblastic leukemias would demonstrate significant chromosomal damage. High-resolution oligo array comparative genomic hybridization demonstrated infrequent aneuploidy but frequent amplification and deletion, with amplifications occurring in a 5:1 ratio with deletions. Many deletions (i.e., Cdkn2a, Ebf1, Pax5, Ikzf1) involved B-cell development genes and tumor suppressor genes, recapitulating deletions occurring in human leukemia. Pathways opposing senescence were frequently deactivated via Cdkn2a deletion or Tbx2 amplification, with corollary gene expression. Additionally, gene expression studies of abnormal pre-leukemic B-precursors showed downregulation of genes involved in chromosomal stability (i.e., Xrcc6) and failure to upregulate DNA repair pathways. We propose a model of leukemogenesis, triggered by pluripotency genes like Prdm14, which involves ongoing DNA damage and failure to activate non-homologous end-joining secondary to aberrant gene expression.

  15. Mouse Lymphoblastic Leukemias Induced by Aberrant Prdm14 Expression Demonstrate Widespread Copy Number Alterations Also Found in Human ALL

    Directory of Open Access Journals (Sweden)

    Stephen J. Simko

    2012-10-01

    Full Text Available Aberrant expression and activation of oncogenes in somatic cells has been associated with cancer initiation. Required for reacquisition of pluripotency in the developing germ cell, PRDM14 initiates lymphoblastic leukemia when misexpressed in murine bone marrow. Activation of pluripotency in somatic cells can lead to aneuploidy and copy number alterations during iPS cell generation, and we hypothesized that PRDM14-induced lymphoblastic leukemias would demonstrate significant chromosomal damage. High-resolution oligo array comparative genomic hybridization demonstrated infrequent aneuploidy but frequent amplification and deletion, with amplifications occurring in a 5:1 ratio with deletions. Many deletions (i.e., Cdkn2a, Ebf1, Pax5, Ikzf1 involved B-cell development genes and tumor suppressor genes, recapitulating deletions occurring in human leukemia. Pathways opposing senescence were frequently deactivated via Cdkn2a deletion or Tbx2 amplification, with corollary gene expression. Additionally, gene expression studies of abnormal pre-leukemic B-precursors showed downregulation of genes involved in chromosomal stability (i.e., Xrcc6 and failure to upregulate DNA repair pathways. We propose a model of leukemogenesis, triggered by pluripotency genes like Prdm14, which involves ongoing DNA damage and failure to activate non-homologous end-joining secondary to aberrant gene expression.

  16. Modelling low Reynolds number vortex-induced vibration problems with a fixed mesh fluid-solid interaction formulation

    Science.gov (United States)

    González Cornejo, Felipe A.; Cruchaga, Marcela A.; Celentano, Diego J.

    2017-11-01

    The present work reports a fluid-rigid solid interaction formulation described within the framework of a fixed-mesh technique. The numerical analysis is focussed on the study of a vortex-induced vibration (VIV) of a circular cylinder at low Reynolds number. The proposed numerical scheme encompasses the fluid dynamics computation in an Eulerian domain where the body is embedded using a collection of markers to describe its shape, and the rigid solid's motion is obtained with the well-known Newton's law. The body's velocity is imposed on the fluid domain through a penalty technique on the embedded fluid-solid interface. The fluid tractions acting on the solid are computed from the fluid dynamic solution of the flow around the body. The resulting forces are considered to solve the solid motion. The numerical code is validated by contrasting the obtained results with those reported in the literature using different approaches for simulating the flow past a fixed circular cylinder as a benchmark problem. Moreover, a mesh convergence analysis is also done providing a satisfactory response. In particular, a VIV problem is analyzed, emphasizing the description of the synchronization phenomenon.

  17. Differential viral levels and immune gene expression in three stocks of Apis mellifera induced by different numbers of Varroa destructor.

    Science.gov (United States)

    Khongphinitbunjong, Kitiphong; de Guzman, Lilia I; Tarver, Matthew R; Rinderer, Thomas E; Chen, Yanping; Chantawannakul, Panuwan

    2015-01-01

    The viral levels and immune responses of Italian honey bees (IHB), Russian honey bees (RHB) and an outcross of Varroa Sensitive Hygienic bees (POL) deliberately infested with one or two foundress Varroa were compared. We found that the Deformed wing virus (DWV) level in IHB inoculated with one or two foundress Varroa increased to about 10(3) or 10(5) fold the levels of their uninfested brood. In contrast, POL (10(2) or 10(4) fold) and RHB (10(2) or l0(4) fold) supported a lower increase in DWV levels. The feeding of different stages of Varroa nymphs did not increase DWV levels of their pupal hosts. Analyses of their corresponding Varroa mites showed the same trends: two foundress Varroa yielded higher DWV levels than one foundress, and the addition of nymphs did not increase viral levels. Using the same pupae examined for the presence of viruses, 16 out of 24 genes evaluated showed significant differential mRNA expression levels among the three honey bee stocks. However, only four genes (Defensin, Dscam, PPOact and spaetzle), which were expressed at similar levels in uninfested pupae, were altered by the number of feeding foundress Varroa and levels of DWV regardless of stocks. This research provides the first evidence that immune response profiles of different honey bee stocks are induced by Varroa parasitism. Copyright © 2014 Elsevier Ltd. All rights reserved.

  18. Increasing number and incidence of fall-induced severe head injuries in older adults: nationwide statistics in Finland in 1970-1995 and prediction for the future.

    Science.gov (United States)

    Kannus, P; Palvanen, M; Niemi, S; Parkkari, J; Natri, A; Vuori, I; Järvinen, M

    1999-01-15

    To increase knowledge about recent trends in the number and incidence of various fall-induced injuries among older adults, the authors selected from the National Hospital Discharge Register all patients 60 years of age or older who were admitted to hospitals in Finland for primary treatment of a first fall-induced severe head injury during 1970-1995. Similar patients aged 30-39 years served as a reference group. For the study period, the number and incidence (per 100,000 persons) of fall-induced severe head injuries in Finnish persons 60 years of age or older increased considerably (554 and 85, respectively, in 1970 compared with 1,393 and 144, respectively, in 1995). The age-adjusted incidence of these injuries also increased in women, from 80 in 1970 to 125 in 1995, and in men, from 102 in 1970 to 147 in 1995. In the reference group (patients aged 30-39 years), the absolute numbers and incidences of similar injuries did not show consistent trend changes over time. We conclude that the number of fall-induced severe head injuries in elderly Finnish women and men is increasing at a rate that cannot be explained simply by demographic changes, and therefore vigorous preventive measures should be instituted at once to control the increasing burden of these devastating injuries.

  19. Type, number or both? A population-based matched case-control study on the risk of fall injuries among older people and number of medications beyond fall-inducing drugs.

    Directory of Open Access Journals (Sweden)

    Lucie Laflamme

    Full Text Available Drug use is a modifiable risk factor for fall-related injuries in older people. Whereas the injurious effect of polypharmacy is established, that of low numbers of medications has not been fully ascertained. Neither do we know whether it is the number per se or the type of medications that actually matters. We assessed this question for fall injuries leading to hospitalization.National register-based, population-based, matched case-control study.Community dwellers aged 65+ years living in Sweden between March 2006 and December 2009.Cases (n = 64,399 were identified in the national inpatient register and four controls per case were randomly matched by gender, date of birth and residential area. The association between number of prescribed medications, assessed through linkage with the Swedish prescribed drug register, and the risk of injurious falls was estimated with odds ratios with 95% confidence intervals using conditional logistic regression, adjusted for demographic and health status.The number of medications was associated with an increased risk of fall injury in a dose-response fashion, even after adjustment for marital status, comorbidity and number of fall-risk-inducing drugs (FRIDs. Using ten or more medications was associated with an almost two-fold higher risk (adjusted OR: 1.76, 95% CI: 1.66 to 1.88. When stratified by use (or not of at least one FRID, the association weakened slightly among both non-users (adjusted OR: 1.50, 95% CI: 1.34 to 1.67 and users (adjusted OR: 1.67, 95% CI: 1.58 to 1.77.In older people, not only large but also small numbers of medications may affect the risk for them to sustain injurious falls. Although the mechanisms lying behind this are complex, the finding challenges the prevention strategies targeting either specific types of medications (FRIDs or high numbers of them.

  20. Analytical asymptotic solutions for heat transfer during transient compression filling of spherical and cylindrical pressure vessels in the limit of small Reynolds number

    Science.gov (United States)

    Heath, Melissa; Woodfield, Peter Lloyd; Hall, Wayne

    2017-06-01

    Taking the limit of small Reynolds number for a vessel being filled with compressed gas, the energy equation was found to asymptote to the unsteady heat conduction equation with heat generation and variable density. This equation was solved analytically for cylindrical and spherical geometry. Assuming the density changes linearly with time, a solution is obtained which is identical in form to the constant density solution if the Fourier number is defined using the log-mean density rather than the instantaneous density. At steady state conditions, the Nusselt number based on the diameter for cylinders with aspect ratios larger than 1 rapidly approaches an integer solution of NuD = 8. For cylinders with aspect ratios less than 1, the Nusselt number based on the cylinder length (height) characteristic dimension rapidly approaches NuL = 6. It is shown experimentally and numerically that during compression filling, the heat transfer asymptotically approaches this analytical solution at low Reynolds numbers.

  1. An Interleukin-33-Mast Cell-Interleukin-2 Axis Suppresses Papain-Induced Allergic Inflammation by Promoting Regulatory T Cell Numbers.

    Science.gov (United States)

    Morita, Hideaki; Arae, Ken; Unno, Hirotoshi; Miyauchi, Kousuke; Toyama, Sumika; Nambu, Aya; Oboki, Keisuke; Ohno, Tatsukuni; Motomura, Kenichiro; Matsuda, Akira; Yamaguchi, Sachiko; Narushima, Seiko; Kajiwara, Naoki; Iikura, Motoyasu; Suto, Hajime; McKenzie, Andrew N J; Takahashi, Takao; Karasuyama, Hajime; Okumura, Ko; Azuma, Miyuki; Moro, Kazuyo; Akdis, Cezmi A; Galli, Stephen J; Koyasu, Shigeo; Kubo, Masato; Sudo, Katsuko; Saito, Hirohisa; Matsumoto, Kenji; Nakae, Susumu

    2015-07-21

    House dust mite-derived proteases contribute to allergic disorders in part by disrupting epithelial barrier function. Interleukin-33 (IL-33), produced by lung cells after exposure to protease allergens, can induce innate-type airway eosinophilia by activating natural helper (NH) cells, a member of group 2 innate lymphoid cells (ILC2), to secrete Th2 type-cytokines. Because IL-33 also can induce mast cells (MCs) to secrete Th2 type-cytokines, MCs are thought to cooperate with NH cells in enhancing protease or IL-33-mediated innate-type airway eosinophilia. However, we found that MC-deficient Kit(W-sh/W-sh) mice exhibited exacerbated protease-induced lung inflammation associated with reduced numbers of regulatory T (Treg) cells. Moreover, IL-2 produced by IL-33-stimulated MCs promoted expansion of numbers of Treg cells, thereby suppressing development of papain- or IL-33-induced airway eosinophilia. We have thus identified a unique anti-inflammatory pathway that can limit induction of innate-type allergic airway inflammation mediated by NH cells. Copyright © 2015 Elsevier Inc. All rights reserved.

  2. Creatine supplementation augments the increase in satellite cell and myonuclei number in human skeletal muscle induced by strength training

    DEFF Research Database (Denmark)

    Olsen, Steen Schytte

    2006-01-01

    to strength training (STR) while receiving a timed intake of creatine (STR-CRE) (n= 9), protein (STR-PRO) (n= 8) or placebo (STR-CON) (n= 8), or serving as a non-training control group (CON) (n= 7). Supplementation was given daily (STR-CRE: 6–24 g creatine monohydrate, STR-PRO: 20 g protein, STR-CON: placebo...... number was no longer elevated in STR-CRE, while it remained elevated in STR-PRO and STR-CON. Furthermore, creatine supplementation resulted in an increased number of myonuclei per fibre and increases of 14–17% in MFA at week 4, 8 and 16 (P ... in the later (16 week, +8%) and STR-CON only in the early (week 4, +14%) phases of training, respectively (P CRE a positive relationship was found between the percentage increases in MFA and myonuclei from baseline to week 16, respectively (r= 0.67, P

  3. Leydig cell number and sperm production decrease induced by chronic ametryn exposure: a negative impact on animal reproductive health.

    Science.gov (United States)

    Dantas, T A; Cancian, G; Neodini, D N R; Mano, D R S; Capucho, C; Predes, F S; Pulz, R Barbieri; Pigoso, A A; Dolder, H; Severi-Aguiar, G D C

    2015-06-01

    Ametryn is an herbicide used to control broadleaf and grass weeds and its acute and chronic toxicity is expected to be low. Since toxicological data on ametryn is scarce, the aim of this study was to evaluate rat reproductive toxicity. Thirty-six adult male Wistar rats (90 days) were divided into three groups: Co (control) and T1 and T2 exposed to 15 and 30 mg/kg/day of ametryn, respectively, for 56 days. Testicular analysis demonstrated that ametryn decreased sperm number per testis, daily sperm production, and Leydig cell number in both treated groups, although little perceptible morphological change has been observed in seminiferous tubule structure. Lipid peroxidation was higher in group T2, catalase activity decreased in T1 group, superoxide dismutase activity diminished, and a smaller number of sulphydryl groups of total proteins were verified in both exposed groups, suggesting oxidative stress. These results showed negative ametryn influence on the testes and can compromise animal reproductive performance and survival.

  4. Contrasting Plasticity in Ovariole Number Induced by A Dietary Effect of the Host Plants between Cactophilic Drosophila Species

    Directory of Open Access Journals (Sweden)

    Daniela Peluso

    2016-05-01

    Full Text Available Under the preference-performance hypothesis, natural selection will favor females that choose oviposition sites that optimize the fitness of their offspring. Such a preference-performance relationship may entail important consequences mainly on fitness-related traits. We used the well-characterized cactus-Drosophila system to investigate the reproductive capacity in the pair of sibling species D. buzzatii and D. koepferae reared in two alternative host plants. According to our hypothesis, ovariole number (as a proxy of reproductive capacity depends on host plant selection. Our results indicate that the capacity of D. buzzatii showed to be mild, only increasing the number of ovarioles by as much as 10% when reared in its preferred host. In contrast, D. koepferae exhibited a similar reproductive capacity across host cacti, even though it showed a preference for its primary host cactus. Our study also revealed that D. buzzatii has a larger genetic variation for phenotypic plasticity than its sibling, although ovariole number did not show clear-cut differences between species. We will discuss the weak preference-performance pattern observed in these cactophilic species in the light of nutritional and toxicological differences found between the natural host plants.

  5. Vortex-induced vibrations of circular cylinder in cross flow at supercritical Reynolds numbers; Chorinkai Reynolds su ryoiki ni okeru enchu no uzu reiki shindo

    Energy Technology Data Exchange (ETDEWEB)

    Kawamura, T.; Nakao, T.; Takahashi, M.; Hayashi, M.; Goto, N. [Hitachi, Ltd., Tokyo (Japan)

    1999-07-25

    Vortex-induced vibrations were measured for a circular cylinder subjected to a water cross flow at supercritical Reynolds numbers for a wide range of reduced velocities. Turbulence intensities were changed from 1% to 13% in order to investigate the effect of the Strouhal number on the region of synchronization by symmetrical and Karman vortex shedding. The reduced damping of the test cylinder was about 0.1 in water. The surface roughness of the cylinder was a mirror-polished surface. Strouhal number decreased from about 0.48 to 0.29 with increasing turbulence intensity. Synchronized vibrations were observed even at supercritical Reynolds numbers where fluctuating fluid force was small. Reduced velocities at which drag and lift direction lock-in by Karman vortex shedding were initiated decreased with increasing Strouhal number. When Strouhal number was about 0.29, the self-excited vibration in drag direction by symmetrical vortex shedding began at which the frequency ratio of Karman vortex shedding frequency to the natural frequency of cylinder was 0.32. (author)

  6. Ultimate regime of high Rayleigh number convection in a porous medium.

    Science.gov (United States)

    Hewitt, Duncan R; Neufeld, Jerome A; Lister, John R

    2012-06-01

    Well-resolved direct numerical simulations of 2D Rayleigh-Bénard convection in a porous medium are presented for Rayleigh numbers Ra≤4×10(4) which reveal that, contrary to previous indications, the linear classical scaling for the Nusselt number, Nu~Ra, is attained asymptotically. The flow dynamics are analyzed, and the interior of the vigorously convecting system is shown to be increasingly well described as Ra→∞ by a simple columnar "heat-exchanger" model with a single horizontal wave number k and a linear background temperature field. The numerical results are approximately fitted by k~Ra(0.4).

  7. Restricted nutrition-induced low birth weight, low number of nephrons and glomerular mesangium injury in Japanese quail.

    Science.gov (United States)

    Nishimura, H; Yaoita, E; Nameta, M; Yamaguchi, K; Sato, M; Ihoriya, C; Zhao, L; Kawachi, H; Sasaki, T; Ikezumi, Y; Ouchi, Y; Kashihara, N; Yamamoto, T

    2017-06-01

    Insufficient nutrition during the perinatal period causes structural alterations in humans and experimental animals, leading to increased vulnerability to diseases in later life. Japanese quail, Coturnix japonica, in which partial (8-10%) egg white was withdrawn (EwW) from eggs before incubation had lower birth weights than controls (CTs). EwW birds also had reduced hatching rates, smaller glomeruli and lower embryo weight. In EwW embryos, the surface condensate area containing mesenchymal cells was larger, suggesting that delayed but active nephrogenesis takes place. In mature EwW quail, the number of glomeruli in the cortical region (mm2) was significantly lower (CT 34.7±1.4, EwW 21.0±1.2); capillary loops showed focal ballooning, and mesangial areas were distinctly expanded. Immunoreactive cell junction proteins, N-cadherin and podocin, and slit diaphragms were clearly seen. With aging, the mesangial area and glomerular size continued to increase and were significantly larger in EwW quail, suggesting compensatory hypertrophy. Furthermore, apoptosis measured by terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick-end labeling analysis was higher in EwWs than in CTs on embryonic day 15 and postnatal day 4 (D4). Similarly, plasma glucocorticoid (corticosterone) was higher (Pquail. These results suggest that although nephrogenic activity is high in low-nutrition quail during the perinatal period, delayed development and increased apoptosis may result in a lower number of mature nephrons. Damaged or incompletely mature mesangium may trigger glomerular injury, leading in later life to nephrosclerosis. The present study shows that birds serve as a model for 'fetal programming,' which appears to have evolved phylogenetically early.

  8. Factor-Reduced Human Induced Pluripotent Stem Cells Efficiently Differentiate into Neurons Independent of the Number of Reprogramming Factors.

    Science.gov (United States)

    Hermann, Andreas; Kim, Jeong Beom; Srimasorn, Sumitra; Zaehres, Holm; Reinhardt, Peter; Schöler, Hans R; Storch, Alexander

    2016-01-01

    Reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) by overexpression of the transcription factors OCT4, SOX2, KLF4, and c-Myc holds great promise for the development of personalized cell replacement therapies. In an attempt to minimize the risk of chromosomal disruption and to simplify reprogramming, several studies demonstrated that a reduced set of reprogramming factors is sufficient to generate iPSC. We recently showed that a reduction of reprogramming factors in murine cells not only reduces reprogramming efficiency but also may worsen subsequent differentiation. To prove whether this is also true for human cells, we compared the efficiency of neuronal differentiation of iPSC generated from fetal human neural stem cells with either one (OCT4; hiPSC1F-NSC) or two (OCT4, KLF4; hiPSC2F-NSC) reprogramming factors with iPSC produced from human fibroblasts using three (hiPSC3F-FIB) or four reprogramming factors (hiPSC4F-FIB). After four weeks of coculture with PA6 stromal cells, neuronal differentiation of hiPSC1F-NSC and hiPSC2F-NSC was as efficient as iPSC3F-FIB or iPSC4F-FIB. We conclude that a reduction of reprogramming factors in human cells does reduce reprogramming efficiency but does not alter subsequent differentiation into neural lineages. This is of importance for the development of future application of iPSC in cell replacement therapies.

  9. Factor-Reduced Human Induced Pluripotent Stem Cells Efficiently Differentiate into Neurons Independent of the Number of Reprogramming Factors

    Directory of Open Access Journals (Sweden)

    Andreas Hermann

    2016-01-01

    Full Text Available Reprogramming of somatic cells into induced pluripotent stem cells (iPSCs by overexpression of the transcription factors OCT4, SOX2, KLF4, and c-Myc holds great promise for the development of personalized cell replacement therapies. In an attempt to minimize the risk of chromosomal disruption and to simplify reprogramming, several studies demonstrated that a reduced set of reprogramming factors is sufficient to generate iPSC. We recently showed that a reduction of reprogramming factors in murine cells not only reduces reprogramming efficiency but also may worsen subsequent differentiation. To prove whether this is also true for human cells, we compared the efficiency of neuronal differentiation of iPSC generated from fetal human neural stem cells with either one (OCT4; hiPSC1F-NSC or two (OCT4, KLF4; hiPSC2F-NSC reprogramming factors with iPSC produced from human fibroblasts using three (hiPSC3F-FIB or four reprogramming factors (hiPSC4F-FIB. After four weeks of coculture with PA6 stromal cells, neuronal differentiation of hiPSC1F-NSC and hiPSC2F-NSC was as efficient as iPSC3F-FIB or iPSC4F-FIB. We conclude that a reduction of reprogramming factors in human cells does reduce reprogramming efficiency but does not alter subsequent differentiation into neural lineages. This is of importance for the development of future application of iPSC in cell replacement therapies.

  10. Transport phenomena of carbon nanotubes and bioconvection nanoparticles on stagnation point flow in presence of induced magnetic field

    Science.gov (United States)

    Iqbal, Z.; Azhar, Ehtsham; Maraj, E. N.

    2017-07-01

    This article is a numerical study of stagnation point flow of carbon nanotubes over an elongating sheet in presence of induced magnetic field submerged in bioconvection nanoparticles. Two types of carbon nanotubes are considered i.e. single wall carbon nanotube and multi wall carbon nanotube mixed in based fluid taken to be water as well as kerosene-oil. The emphasis of present study is to examine effect of induced magnetic field on boundary layer flows along with influence of SWCNT and MWCNT. Physical problem is mathematically modeled and simplified by using appropriate similarity transformations. Shooting method with Runge-Kutta of order 5 is employed to compute numerical results for non-dimensional velocity, induced magnetic field and temperature. The effects of pertinent parameters are portrayed through graphs. Numerical values of skinfriction coefficient and Nusselt number are tabulated to study the behaviors at the stretching surface. It is depicted that induced magnetic field is an increasing function of solid nanoparticles volumetric fraction. Moreover, MWCNT contributes in rising induced magnetic field more as compared to SWCNT for both water and kerosene-oil based fluids.

  11. Stationary plume induced by carbon dioxide dissolution

    International Nuclear Information System (INIS)

    Nadal, F.; Meunier, P.; Pouligny, B.; Laurichesse, E.

    2013-01-01

    In this paper, laminar convection flows induced by carbon dioxide absorption are addressed from experimental, numerical and theoretical points of view. A vertical glass tube (of centimetre scale) filled with distilled water is subjected to a sudden increase in the partial pressure of carbon dioxide. As a result of the diffusion of the gas into the unsaturated solution, a thin layer of fluid located underneath the surface becomes heavier. This initial density gradient first destabilizes to form a plume, which goes downwards through the entire cell. After a first transient pulsating regime (periodic succession of such Rayleigh-Benard plumes), a stationary flow settles in the tube, which is maintained by the constant supply of gas at the surface. At late stages, this stationary regime is followed by an aperiodic regime, which lasts until the complete saturation of the solution (thermodynamic equilibrium). The present study only focuses on the stationary regime, whose characteristics appear to be almost independent of the Bond number and the aspect ratio but strongly dependent on the chemical Rayleigh number. Three decades of Rayleigh numbers are explored using particle image velocimetry measurements, which allows for a precise determination of the scaling exponents for the vertical velocity amplitude and the plume width. The assumption that gravity and a constant pressure gradient balance the viscous effects enables us to derive an analytic expression for the stationary vertical velocity on the axis, which scales as Ra 2/3 (ln Ra) 1/3 . As a consequence, the width of the plume scales as Ra -1/6 (ln Ra) -1/3 and the mass Nusselt number as (Ra= ln Ra) 1/3 . These scalings are in excellent agreement with the experimental and numerical results. The multiplicative constants of these scalings can also be calculated and show a fairly good agreement if a rigid boundary condition (no-slip) is assumed at the free surface. (authors)

  12. The Number of Point Mutations in Induced Pluripotent Stem Cells and Nuclear Transfer Embryonic Stem Cells Depends on the Method and Somatic Cell Type Used for Their Generation.

    Science.gov (United States)

    Araki, Ryoko; Mizutani, Eiji; Hoki, Yuko; Sunayama, Misato; Wakayama, Sayaka; Nagatomo, Hiroaki; Kasama, Yasuji; Nakamura, Miki; Wakayama, Teruhiko; Abe, Masumi

    2017-05-01

    Induced pluripotent stem cells hold great promise for regenerative medicine but point mutations have been identified in these cells and have raised serious concerns about their safe use. We generated nuclear transfer embryonic stem cells (ntESCs) from both mouse embryonic fibroblasts (MEFs) and tail-tip fibroblasts (TTFs) and by whole genome sequencing found fewer mutations compared with iPSCs generated by retroviral gene transduction. Furthermore, TTF-derived ntESCs showed only a very small number of point mutations, approximately 80% less than the number observed in iPSCs generated using retrovirus. Base substitution profile analysis confirmed this greatly reduced number of point mutations. The point mutations in iPSCs are therefore not a Yamanaka factor-specific phenomenon but are intrinsic to genome reprogramming. Moreover, the dramatic reduction in point mutations in ntESCs suggests that most are not essential for genome reprogramming. Our results suggest that it is feasible to reduce the point mutation frequency in iPSCs by optimizing various genome reprogramming conditions. We conducted whole genome sequencing of ntES cells derived from MEFs or TTFs. We thereby succeeded in establishing TTF-derived ntES cell lines with far fewer point mutations. Base substitution profile analysis of these clones also indicated a reduced point mutation frequency, moving from a transversion-predominance to a transition-predominance. Stem Cells 2017;35:1189-1196. © 2017 AlphaMed Press.

  13. Effect of pulse repetition rate and number of pulses in the analysis of polypropylene and high density polyethylene by nanosecond infrared laser induced breakdown spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Leme, Flavio O. [Laboratorio de Quimica Analitica ' Henrique Bergamin Filho' , Centro de Energia Nuclear na Agricultura, Universidade de Sao Paulo, Av. Centenario 303, 13416-000 Piracicaba, SP (Brazil); Godoi, Quienly [Laboratorio de Quimica Analitica ' Henrique Bergamin Filho' , Centro de Energia Nuclear na Agricultura, Universidade de Sao Paulo, Av. Centenario 303, 13416-000 Piracicaba, SP (Brazil); Departamento de Quimica, Universidade Federal de Sao Carlos, Rod. Washington Luis, km 235, 13565-905 Sao Carlos, SP (Brazil); Kiyataka, Paulo H.M. [Centro de Tecnologia de Embalagens, Instituto de Tecnologia de Alimentos, Av. Brasil 2880, 13070-178 Campinas, SP (Brazil); Santos, Dario [Departamento de Ciencias Exatas e da Terra, Universidade Federal de Sao Paulo, Rua Prof. Artur Riedel 275, 09972-270 Diadema, SP (Brazil); Agnelli, Jose A.M. [Departamento de Engenharia de Materiais, Universidade Federal de Sao Carlos, Rod. Washington Luis, km 235, 13565-905 Sao Carlos, SP (Brazil); and others

    2012-02-01

    Pulse repetition rates and the number of laser pulses are among the most important parameters that do affect the analysis of solid materials by laser induced breakdown spectroscopy, and the knowledge of their effects is of fundamental importance for suggesting analytical strategies when dealing with laser ablation processes of polymers. In this contribution, the influence of these parameters in the ablated mass and in the features of craters was evaluated in polypropylene and high density polyethylene plates containing pigment-based PbCrO{sub 4}. Surface characterization and craters profile were carried out by perfilometry and scanning electron microscopy. Area, volume and profile of craters were obtained using Taylor Map software. A laser induced breakdown spectroscopy system consisted of a Q-Switched Nd:YAG laser (1064 nm, 5 ns) and an Echelle spectrometer equipped with ICCD detector were used. The evaluated operating conditions consisted of 10, 25 and 50 laser pulses at 1, 5 and 10 Hz, 250 mJ/pulse (85 J cm{sup -2}), 2 {mu}s delay time and 6 {mu}s integration time gate. Differences in the topographical features among craters of both polymers were observed. The decrease in the repetition rate resulted in irregular craters and formation of edges, especially in polypropylene sample. The differences in the topographical features and ablated masses were attributed to the influence of the degree of crystallinity, crystalline melting temperature and glass transition temperature in the ablation process of the high density polyethylene and polypropylene. It was also observed that the intensities of chromium and lead emission signals obtained at 10 Hz were two times higher than at 5 Hz by keeping the number of laser pulses constant.

  14. The Effect of N-acetyl-cysteine on Memory Retrieval and the Number of Intact Neurons of Hippocampal CA1 Area in Streptozotocin-induced Alzheimeric Male Rats

    Directory of Open Access Journals (Sweden)

    Niloufar Darbandi

    2018-01-01

    Full Text Available Abstract Background: Alzheimer is a neurodegenerative disease wich caused memory impairment, reduced cognitive functions, intellectual ability and behavior changes. In this study, the effect of N-acetyl-cysteine (NAC as a strong antioxidant on memory deficiency and number of CA1 pyramidal neurons in Streptozotocine (STZ - induced Alzheimeric rats were studied. Materials and Methods: 32 Male Wistar rats were divided into four groups: sham group, streptozotocin group, treated group with streptozotocin plus N-acetyl-cysteine, and treated group with N-acetyl-cysteine alone. Intracerebroventricular (ICV administration of STZ was done in the first and the third day of surgery and i.p injection of N-acetyl-cysteine was done in the fourth of surgery. After the memory test, the animals were killed and their brains were fixed and density of intact neurons in the CA1 area of the hippocampus was investigated. Statistical analysis was performed with software SPSS, ANOVA and Prisme software. The level of statistical significance was set at p 0.05. Conclusion: N-acetyl-cysteine improved memory retrieval and hippocampal CA1 area intact neurons in streptozotocin-induced Alzheimeric male rats.

  15. Radiated flow of chemically reacting nanoliquid with an induced magnetic field across a permeable vertical plate

    Directory of Open Access Journals (Sweden)

    B. Mahanthesh

    Full Text Available Impact of induced magnetic field over a flat porous plate by utilizing incompressible water-copper nanoliquid is examined analytically. Flow is supposed to be laminar, steady and two-dimensional. The plate is subjected to a regular free stream velocity as well as suction velocity. Flow formulation is developed by considering Maxwell–Garnetts (MG and Brinkman models of nanoliquid. Impacts of thermal radiation, viscous dissipation, temperature dependent heat source/sink and first order chemical reaction are also retained. The subjected non-linear problems are non-dimensionalized and analytic solutions are presented via series expansion method. The graphs are plotted to analyze the influence of pertinent parameters on flow, magnetism, heat and mass transfer fields as well as friction factor, current density, Nusselt and Sherwood numbers. It is found that friction factor at the plate is more for larger magnetic Prandtl number. Also the rate of heat transfer decayed with increasing nanoparticles volume fraction and the strength of magnetism. Keywords: Induced magnetic field, Nanoliquids, Heat source/sink, Series expansion method, Chemical reaction, Thermal radiation

  16. The Determination of Neutron-Induced Reaction Cross Section Data on Even-Even, Magic- Number Nuclide Chromium 52 Using EXIFON Code

    International Nuclear Information System (INIS)

    Jonah, S.A.

    2013-01-01

    The EXIFON code version 2.0 is a calculational tool, which is based on both many-body theory and random matrix physics. In this work, it has been used to calculate neutron induced reaction cross section data from 0 to 20 MeV on an even-even, magic number nuclide 52 Cr with neutron number, N=28. Specifically, the (n,p), (n,α) and (n,2n) reaction cross section data were calculated as functions of incident energy of neutrons. Data obtained from the experimental data in the IAEA, EXFOR data Library and recommended data libraries around the globe, JENDL, ENDF and JEFF were used to validate the calculated data. The data indicate that the calculated data without shell corrections are in good agreement with experimental data as well as the recommended data from the evaluated data libraries. The calculated results could provide useful insight into the choice of some input parameters near closed shells using the EXIFON code.

  17. Numerical studies of vortex-induced extinction/reignition relevant to the near-field of high-Reynolds number jets

    Science.gov (United States)

    Venugopal, Rishikesh; Abraham, John

    2009-05-01

    This work is motivated by the need to understand physical mechanisms governing near-field phenomena, such as flame lift-off, in high-Reynolds number jet flames. Numerical studies of vortex-induced flame extinction/reignition are performed for conditions representative of the near field of high-Reynolds number (˜100 000) jets under high pressure and temperature conditions. The governing equations for compressible, viscous, and reacting flows are solved along with a single-step irreversible chemical kinetic model for gaseous n-heptane oxidation. Extinction/reignition phenomena, influenced by unsteady and curvature effects, are observed. Unsteady flamelet/progress variable models are shown to accurately describe the flame response during extinction/reignition observed in the flame-vortex studies. Furthermore, while unsteady effects on extinction/reignition are found to diminish with weaker vortices and relatively strong flames, curvature effects are found to increase with relatively thicker flames. The observed flame-vortex interaction regimes are summarized on an outcome diagram, which is useful to understand the nature of localized flame dynamics in the near field of jet flames.

  18. Sagan numbers

    OpenAIRE

    Mendonça, J. Ricardo G.

    2012-01-01

    We define a new class of numbers based on the first occurrence of certain patterns of zeros and ones in the expansion of irracional numbers in a given basis and call them Sagan numbers, since they were first mentioned, in a special case, by the North-american astronomer Carl E. Sagan in his science-fiction novel "Contact." Sagan numbers hold connections with a wealth of mathematical ideas. We describe some properties of the newly defined numbers and indicate directions for further amusement.

  19. Fibonacci numbers

    CERN Document Server

    Vorob'ev, Nikolai Nikolaevich

    2011-01-01

    Fibonacci numbers date back to an 800-year-old problem concerning the number of offspring born in a single year to a pair of rabbits. This book offers the solution and explores the occurrence of Fibonacci numbers in number theory, continued fractions, and geometry. A discussion of the ""golden section"" rectangle, in which the lengths of the sides can be expressed as a ration of two successive Fibonacci numbers, draws upon attempts by ancient and medieval thinkers to base aesthetic and philosophical principles on the beauty of these figures. Recreational readers as well as students and teacher

  20. Number names and number understanding

    DEFF Research Database (Denmark)

    Ejersbo, Lisser Rye; Misfeldt, Morten

    2014-01-01

    through using mathematical names for the numbers such as one-ten-one for 11 and five-ten-six for 56. The project combines the renaming of numbers with supporting the teaching with the new number names. Our hypothesis is that Danish children have more difficulties learning and working with numbers, because...... the Danish number names are more complicated than in other languages. Keywords: A research project in grade 0 and 1th in a Danish school, Base-10 system, two-digit number names, semiotic, cognitive perspectives....

  1. Chronic wheel running-induced reduction of extinction and reinstatement of methamphetamine seeking in methamphetamine dependent rats is associated with reduced number of periaqueductal gray dopamine neurons.

    Science.gov (United States)

    Sobieraj, Jeffery C; Kim, Airee; Fannon, McKenzie J; Mandyam, Chitra D

    2016-01-01

    Exercise (physical activity) has been proposed as a treatment for drug addiction. In rodents, voluntary wheel running reduces cocaine and nicotine seeking during extinction, and reinstatement of cocaine seeking triggered by drug-cues. The purpose of this study was to examine the effects of chronic wheel running during withdrawal and protracted abstinence on extinction and reinstatement of methamphetamine seeking in methamphetamine dependent rats, and to determine a potential neurobiological correlate underlying the effects. Rats were given extended access to methamphetamine (0.05 mg/kg, 6 h/day) for 22 sessions. Rats were withdrawn and were given access to running wheels (wheel runners) or no wheels (sedentary) for 3 weeks after which they experienced extinction and reinstatement of methamphetamine seeking. Extended access to methamphetamine self-administration produced escalation in methamphetamine intake. Methamphetamine experience reduced running output, and conversely, access to wheel running during withdrawal reduced responding during extinction and, context- and cue-induced reinstatement of methamphetamine seeking. Immunohistochemical analysis of brain tissue demonstrated that wheel running during withdrawal did not regulate markers of methamphetamine neurotoxicity (neurogenesis, neuronal nitric oxide synthase, vesicular monoamine transporter-2) and cellular activation (c-Fos) in brain regions involved in relapse to drug seeking. However, reduced methamphetamine seeking was associated with running-induced reduction (and normalization) of the number of tyrosine hydroxylase immunoreactive neurons in the periaqueductal gray (PAG). The present study provides evidence that dopamine neurons of the PAG region show adaptive biochemical changes during methamphetamine seeking in methamphetamine dependent rats and wheel running abolishes these effects. Given that the PAG dopamine neurons project onto the structures of the extended amygdala, the present findings also

  2. Chronic wheel running-induced reduction of extinction and reinstatement of methamphetamine seeking in methamphetamine dependent rats is associated with reduced number of periaqueductal gray dopamine neurons

    Science.gov (United States)

    Sobieraj, Jeffery C.; Kim, Airee; Fannon, McKenzie J.; Mandyam, Chitra D.

    2015-01-01

    Exercise (physical activity) has been proposed as a treatment for drug addiction. In rodents, voluntary wheel running reduces cocaine and nicotine seeking during extinction, and reinstatement of cocaine seeking triggered by drug cues. The purpose of this study was to examine the effects of chronic wheel running during withdrawal and protracted abstinence on extinction and reinstatement of methamphetamine seeking in methamphetamine dependent rats, and to determine a potential neurobiological correlate underlying the effects. Rats were given extended access to methamphetamine (0.05 mg/kg, 6h/day) for 22 sessions. Rats were withdrawn and were given access to running wheels (wheel runners) or no wheels (sedentary) for three weeks after which they experienced extinction and reinstatement of methamphetamine seeking. Extended access to methamphetamine self-administration produced escalation in methamphetamine intake. Methamphetamine experience reduced running output, and conversely, access to wheel running during withdrawal reduced responding during extinction and, context- and cue-induced reinstatement of methamphetamine seeking. Immunohistochemical analysis of brain tissue demonstrated that wheel running during withdrawal did not regulate markers of methamphetamine neurotoxicity (neurogenesis, neuronal nitric oxide synthase, vesicular monoamine transporter-2) and cellular activation (c-Fos) in brain regions involved in relapse to drug seeking. However, reduced methamphetamine seeking was associated with running-induced reduction (and normalization) of the number of tyrosine hydroxylase (TH) immunoreactive neurons in the periaqueductal gray (PAG). The present study provides evidence that dopamine neurons of the PAG region show adaptive biochemical changes during methamphetamine seeking in methamphetamine dependent rats and wheel running abolishes these effects. Given that the PAG dopamine neurons project onto the structures of the extended amygdala, the present findings

  3. Eulerian numbers

    CERN Document Server

    Petersen, T Kyle

    2015-01-01

    This text presents the Eulerian numbers in the context of modern enumerative, algebraic, and geometric combinatorics. The book first studies Eulerian numbers from a purely combinatorial point of view, then embarks on a tour of how these numbers arise in the study of hyperplane arrangements, polytopes, and simplicial complexes. Some topics include a thorough discussion of gamma-nonnegativity and real-rootedness for Eulerian polynomials, as well as the weak order and the shard intersection order of the symmetric group. The book also includes a parallel story of Catalan combinatorics, wherein the Eulerian numbers are replaced with Narayana numbers. Again there is a progression from combinatorics to geometry, including discussion of the associahedron and the lattice of noncrossing partitions. The final chapters discuss how both the Eulerian and Narayana numbers have analogues in any finite Coxeter group, with many of the same enumerative and geometric properties. There are four supplemental chapters throughout, ...

  4. Convection in an ideal gas at high Rayleigh numbers.

    Science.gov (United States)

    Tilgner, A

    2011-08-01

    Numerical simulations of convection in a layer filled with ideal gas are presented. The control parameters are chosen such that there is a significant variation of density of the gas in going from the bottom to the top of the layer. The relations between the Rayleigh, Peclet, and Nusselt numbers depend on the density stratification. It is proposed to use a data reduction which accounts for the variable density by introducing into the scaling laws an effective density. The relevant density is the geometric mean of the maximum and minimum densities in the layer. A good fit to the data is then obtained with power laws with the same exponent as for fluids in the Boussinesq limit. Two relations connect the top and bottom boundary layers: The kinetic energy densities computed from free fall velocities are equal at the top and bottom, and the products of free fall velocities and maximum horizontal velocities are equal for both boundaries.

  5. Transfinite Numbers

    Indian Academy of Sciences (India)

    Transfinite Numbers. What is Infinity? S M Srivastava. In a series of revolutionary articles written during the last quarter of the nineteenth century, the great Ger- man mathematician Georg Cantor removed the age-old mistrust of infinity and created an exceptionally beau- tiful and useful theory of transfinite numbers. This is.

  6. Numerical investigation of the vortex-induced vibration of an elastically mounted circular cylinder at high Reynolds number (Re = 104 and low mass ratio using the RANS code.

    Directory of Open Access Journals (Sweden)

    Niaz Bahadur Khan

    Full Text Available This study numerically investigates the vortex-induced vibration (VIV of an elastically mounted rigid cylinder by using Reynolds-averaged Navier-Stokes (RANS equations with computational fluid dynamic (CFD tools. CFD analysis is performed for a fixed-cylinder case with Reynolds number (Re = 104 and for a cylinder that is free to oscillate in the transverse direction and possesses a low mass-damping ratio and Re = 104. Previously, similar studies have been performed with 3-dimensional and comparatively expensive turbulent models. In the current study, the capability and accuracy of the RANS model are validated, and the results of this model are compared with those of detached eddy simulation, direct numerical simulation, and large eddy simulation models. All three response branches and the maximum amplitude are well captured. The 2-dimensional case with the RANS shear-stress transport k-w model, which involves minimal computational cost, is reliable and appropriate for analyzing the characteristics of VIV.

  7. Effects of Integrating and Non-Integrating Reprogramming Methods on Copy Number Variation and Genomic Stability of Human Induced Pluripotent Stem Cells.

    Science.gov (United States)

    Kang, Xiangjin; Yu, Qian; Huang, Yuling; Song, Bing; Chen, Yaoyong; Gao, Xingcheng; He, Wenyin; Sun, Xiaofang; Fan, Yong

    2015-01-01

    Human-induced pluripotent stem cells (iPSCs) are derived from differentiated somatic cells using defined factors and provide a renewable source of autologous cells for cell therapy. Many reprogramming methods have been employed to generate human iPSCs, including the use of integrating vectors and non-integrating vectors. Maintenance of the genomic integrity of iPSCs is highly desirable if the cells are to be used in clinical applications. Here, using the Affymetrix Cytoscan HD array, we investigated the genomic aberration profiles of 19 human cell lines: 5 embryonic stem cell (ESC) lines, 6 iPSC lines derived using integrating vectors ("integrating iPSC lines"), 6 iPSC lines derived using non-integrating vectors ("non-integrating iPSC lines"), and the 2 parental cell lines from which the iPSCs were derived. The genome-wide copy number variation (CNV), loss of heterozygosity (LOH) and mosaicism patterns of integrating and non-integrating iPSC lines were investigated. The maximum sizes of CNVs in the genomes of the integrating iPSC lines were 20 times higher than those of the non-integrating iPSC lines. Moreover, the total number of CNVs was much higher in integrating iPSC lines than in other cell lines. The average numbers of novel CNVs with a low degree of overlap with the DGV and of likely pathogenic CNVs with a high degree of overlap with the ISCA (International Symposium on Computer Architecture) database were highest in integrating iPSC lines. Different single nucleotide polymorphisms (SNP) calls revealed that, using the parental cell genotype as a reference, integrating iPSC lines displayed more single nucleotide variations and mosaicism than did non-integrating iPSC lines. This study describes the genome stability of human iPSCs generated using either a DNA-integrating or non-integrating reprogramming method, of the corresponding somatic cells, and of hESCs. Our results highlight the importance of using a high-resolution method to monitor genomic aberrations

  8. Effects of Integrating and Non-Integrating Reprogramming Methods on Copy Number Variation and Genomic Stability of Human Induced Pluripotent Stem Cells.

    Directory of Open Access Journals (Sweden)

    Xiangjin Kang

    Full Text Available Human-induced pluripotent stem cells (iPSCs are derived from differentiated somatic cells using defined factors and provide a renewable source of autologous cells for cell therapy. Many reprogramming methods have been employed to generate human iPSCs, including the use of integrating vectors and non-integrating vectors. Maintenance of the genomic integrity of iPSCs is highly desirable if the cells are to be used in clinical applications. Here, using the Affymetrix Cytoscan HD array, we investigated the genomic aberration profiles of 19 human cell lines: 5 embryonic stem cell (ESC lines, 6 iPSC lines derived using integrating vectors ("integrating iPSC lines", 6 iPSC lines derived using non-integrating vectors ("non-integrating iPSC lines", and the 2 parental cell lines from which the iPSCs were derived. The genome-wide copy number variation (CNV, loss of heterozygosity (LOH and mosaicism patterns of integrating and non-integrating iPSC lines were investigated. The maximum sizes of CNVs in the genomes of the integrating iPSC lines were 20 times higher than those of the non-integrating iPSC lines. Moreover, the total number of CNVs was much higher in integrating iPSC lines than in other cell lines. The average numbers of novel CNVs with a low degree of overlap with the DGV and of likely pathogenic CNVs with a high degree of overlap with the ISCA (International Symposium on Computer Architecture database were highest in integrating iPSC lines. Different single nucleotide polymorphisms (SNP calls revealed that, using the parental cell genotype as a reference, integrating iPSC lines displayed more single nucleotide variations and mosaicism than did non-integrating iPSC lines. This study describes the genome stability of human iPSCs generated using either a DNA-integrating or non-integrating reprogramming method, of the corresponding somatic cells, and of hESCs. Our results highlight the importance of using a high-resolution method to monitor genomic

  9. Number theory

    CERN Document Server

    Andrews, George E

    1994-01-01

    Although mathematics majors are usually conversant with number theory by the time they have completed a course in abstract algebra, other undergraduates, especially those in education and the liberal arts, often need a more basic introduction to the topic.In this book the author solves the problem of maintaining the interest of students at both levels by offering a combinatorial approach to elementary number theory. In studying number theory from such a perspective, mathematics majors are spared repetition and provided with new insights, while other students benefit from the consequent simpl

  10. Nice numbers

    CERN Document Server

    Barnes, John

    2016-01-01

    In this intriguing book, John Barnes takes us on a journey through aspects of numbers much as he took us on a geometrical journey in Gems of Geometry. Similarly originating from a series of lectures for adult students at Reading and Oxford University, this book touches a variety of amusing and fascinating topics regarding numbers and their uses both ancient and modern. The author intrigues and challenges his audience with both fundamental number topics such as prime numbers and cryptography, and themes of daily needs and pleasures such as counting one's assets, keeping track of time, and enjoying music. Puzzles and exercises at the end of each lecture offer additional inspiration, and numerous illustrations accompany the reader. Furthermore, a number of appendices provides in-depth insights into diverse topics such as Pascal’s triangle, the Rubik cube, Mersenne’s curious keyboards, and many others. A theme running through is the thought of what is our favourite number. Written in an engaging and witty sty...

  11. Number names and number understanding

    DEFF Research Database (Denmark)

    Ejersbo, Lisser Rye; Misfeldt, Morten

    2014-01-01

    This paper concerns the results from the first year of a three-year research project involving the relationship between Danish number names and their corresponding digits in the canonical base 10 system. The project aims to develop a system to help the students’ understanding of the base 10 system...... the Danish number names are more complicated than in other languages. Keywords: A research project in grade 0 and 1th in a Danish school, Base-10 system, two-digit number names, semiotic, cognitive perspectives....

  12. Funny Numbers

    Directory of Open Access Journals (Sweden)

    Theodore M. Porter

    2012-12-01

    Full Text Available The struggle over cure rate measures in nineteenth-century asylums provides an exemplary instance of how, when used for official assessments of institutions, these numbers become sites of contestation. The evasion of goals and corruption of measures tends to make these numbers “funny” in the sense of becoming dis-honest, while the mismatch between boring, technical appearances and cunning backstage manipulations supplies dark humor. The dangers are evident in recent efforts to decentralize the functions of governments and corporations using incen-tives based on quantified targets.

  13. Number Guessing

    Science.gov (United States)

    Sezin, Fatin

    2009-01-01

    It is instructive and interesting to find hidden numbers by using different positional numeration systems. Most of the present guessing techniques use the binary system expressed as less-than, greater-than or present-absent type information. This article describes how, by employing four cards having integers 1-64 written in different colours, one…

  14. Transfinite Numbers

    Indian Academy of Sciences (India)

    this is a characteristic difference between finite and infinite sets and created an immensely useful branch of mathematics based on this idea which had a great impact on the whole of mathe- matics. For example, the question of what is a number (finite or infinite) is almost a philosophical one. However Cantor's work turned it ...

  15. Transfinite Numbers

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 2; Issue 3. Transfinite Numbers - What is Infinity? S M Srivastava. General Article Volume 2 Issue 3 March 1997 pp 58-68. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/002/03/0058-0068 ...

  16. Long-term aerobic swimming training by rats reduces the number of aberrant crypt foci in 1,2-dimethylhydrazine-induced colon cancer

    Directory of Open Access Journals (Sweden)

    W. Lunz

    2008-11-01

    Full Text Available We determined the effect of long-term aerobic swimming training regimens of different intensities on colonic carcinogenesis in rats. Male Wistar rats (11 weeks old were given 4 subcutaneous injections (40 mg/kg body weight each of 1,2-dimethyl-hydrazine (DMH, dissolved in 0.9% NaCl containing 1.5% EDTA, pH 6.5, at 3-day intervals and divided into three exercise groups that swam with 0% body weight (EG1, N = 11, 2% body weight (EG2, N = 11, and 4% body weight of load (EG3, N = 10, 20 min/day, 5 days/week for 35 weeks, and one sedentary control group (CG, N = 10. At sacrifice, the colon was removed and counted for tumors and aberrant crypt foci. Tumor size was measured and intra-abdominal fat was weighed. The mean number of aberrant crypt foci was reduced only for EG2 compared to CG (26.21 ± 2.99 vs 36.40 ± 1.53 crypts; P < 0.05. Tumor incidence was not significantly different among groups (CG: 90%; EG1: 72.7%; EG2: 90%; EG3: 80%. Swimming training did not affect either tumor multiplicity (CG: 2.30 ± 0.58; EG1: 2.09 ± 0.44; EG2: 1.27 ± 0.19; EG3: 1.50 ± 0.48 tumors or size (CG: 1.78 ± 0.24; EG1: 1.81 ± 0.14; EG2: 1.55 ± 0.21; EG3: 2.17 ± 0.22 cm³. Intra-abdominal fat was not significantly different among groups (CG: 10.54 ± 2.73; EG1: 6.12 ± 1.15; EG2: 7.85 ± 1.24; EG3: 5.11 ± 0.74 g. Aerobic swimming training with 2% body weight of load protected against the DMH-induced preneoplastic colon lesions, but not against tumor development in the rat.

  17. Numerical analysis of jet impingement heat transfer at high jet Reynolds number and large temperature difference

    DEFF Research Database (Denmark)

    Jensen, Michael Vincent; Walther, Jens Honore

    2013-01-01

    Jet impingement heat transfer from a round gas jet to a flat wall was investigated numerically for a ratio of 2 between the jet inlet to wall distance and the jet inlet diameter. The influence of turbulence intensity at the jet inlet and choice of turbulence model on the wall heat transfer...... was investigated at a jet Reynolds number of 1.66 × 105 and a temperature difference between jet inlet and wall of 1600 K. The focus was on the convective heat transfer contribution as thermal radiation was not included in the investigation. A considerable influence of the turbulence intensity at the jet inlet...... to about 100% were observed. Furthermore, the variation in stagnation point heat transfer was examined for jet Reynolds numbers in the range from 1.10 × 105 to 6.64 × 105. Based on the investigations, a correlation is suggested between the stagnation point Nusselt number, the jet Reynolds number...

  18. Dual solutions for MHD stagnation-point flow of a nanofluid over a stretching surface with induced magneticfield

    Directory of Open Access Journals (Sweden)

    Sandeep Naramgari

    2015-11-01

    Full Text Available Present study deals with the buoyancy-driven MHD mixed convection stagnation-point flow, heat and mass transfer of a nanofluid over a non-isothermal stretching sheet in presence of induced magneticfield, radiation, chemical reaction, suction/injection and heat source/sink. The basic governing partial differential equations are reduced to a set of ordinary differential equations by using appropriate similarity transformation. The resulting system is solved numerically by bvp5c Matlab package. Numerical results are validated by comparing with the published results. The influence of non-dimensional governing parameters on velocity, induced magneticfield, temperature and concentration profiles along with coefficient of skin friction, local Nusselt and Sherwood numbers are discussed and presented with the help of graphs and tables. Comparisons are made with the existed studies. Results indicate that dual solutions exists only for certain range of suction/ injection parameter and injection parameter have tendency to enhance the momentum, thermal and concentration boundary layer thickness.

  19. Rotating Rayleigh-Bénard convection at low Prandtl number

    Science.gov (United States)

    Aguirre Guzman, Andres; Ostilla-Monico, Rodolfo; Clercx, Herman; Kunnen, Rudie

    2017-11-01

    Most geo- and astrophysical convective flows are too remote or too complex for direct measurements of the physical quantities involved, and thus a reduced framework with the main physical constituents is beneficial. This approach is given by the problem of rotating Rayleigh-Bénard convection (RRBC). For large-scale systems, the governing parameters of RRBC take extreme values, leading to the geostrophic turbulent regime. We perform Direct Numerical Simulations to investigate the transition to this regime at low Prandtl number (Pr). In low- Pr fluids, thermal diffusivity dominates over momentum diffusivity; we use Pr = 0.1 , relevant to liquid metals. In particular, we study the convective heat transfer (Nusselt number Nu) as a function of rotation (assessed by the Ekman number Ek). The strength of the buoyant forcing (Rayleigh number Ra) is Ra = 1 ×1010 to ensure turbulent convection. Varying Ek , we observe a change of the power-law scaling Nu Ekβ that suggests a transition to geostrophic turbulence, which is likely to occur at Ek = 9 ×10-7 . The thermal boundary layer thickness, however, may suggest a transition at lower Ekman numbers, indicating that perhaps not all statistical quantities show a transitional behaviour at the same Ek .

  20. Experimental study of the vortex-induced vibration of drilling risers under the shear flow with the same shear parameter at the different Reynolds numbers.

    Directory of Open Access Journals (Sweden)

    Mao Liangjie

    Full Text Available A considerable number of studies for VIV under the uniform flow have been performed. However, research on VIV under shear flow is scarce. An experiment for VIV under the shear flow with the same shear parameter at the two different Reynolds numbers was conducted in a deep-water offshore basin. Various measurements were obtained by the fiber bragg grating strain sensors. Experimental data were analyzed by modal analysis method. Results show several valuable features. First, the corresponding maximum order mode of the natural frequency for shedding frequency is the maximum dominant vibration mode and multi-modal phenomenon is appeared in VIV under the shear flow, and multi-modal phenomenon is more apparent at the same shear parameter with an increasing Reynolds number under the shear flow effect. Secondly, the riser vibrates at the natural frequency and the dominant vibration frequency increases for the effect of the real-time tension amplitude under the shear flow and the IL vibration frequency is the similar with the CF vibration frequency at the Reynolds number of 1105 in our experimental condition and the IL dominant frequency is twice the CF dominant frequency with an increasing Reynolds number. In addition, the displacement trajectories at the different locations of the riser appear the same shape and the shape is changed at the same shear parameter with an increasing Reynolds number under the shear flow. The diagonal displacement trajectories are observed at the low Reynolds number and the crescent-shaped displacement trajectories appear with an increasing Reynolds number under shear flow in the experiment.

  1. Experimental study of the vortex-induced vibration of drilling risers under the shear flow with the same shear parameter at the different Reynolds numbers.

    Science.gov (United States)

    Liangjie, Mao; Qingyou, Liu; Shouwei, Zhou

    2014-01-01

    A considerable number of studies for VIV under the uniform flow have been performed. However, research on VIV under shear flow is scarce. An experiment for VIV under the shear flow with the same shear parameter at the two different Reynolds numbers was conducted in a deep-water offshore basin. Various measurements were obtained by the fiber bragg grating strain sensors. Experimental data were analyzed by modal analysis method. Results show several valuable features. First, the corresponding maximum order mode of the natural frequency for shedding frequency is the maximum dominant vibration mode and multi-modal phenomenon is appeared in VIV under the shear flow, and multi-modal phenomenon is more apparent at the same shear parameter with an increasing Reynolds number under the shear flow effect. Secondly, the riser vibrates at the natural frequency and the dominant vibration frequency increases for the effect of the real-time tension amplitude under the shear flow and the IL vibration frequency is the similar with the CF vibration frequency at the Reynolds number of 1105 in our experimental condition and the IL dominant frequency is twice the CF dominant frequency with an increasing Reynolds number. In addition, the displacement trajectories at the different locations of the riser appear the same shape and the shape is changed at the same shear parameter with an increasing Reynolds number under the shear flow. The diagonal displacement trajectories are observed at the low Reynolds number and the crescent-shaped displacement trajectories appear with an increasing Reynolds number under shear flow in the experiment.

  2. Effects of Integrating and Non-Integrating Reprogramming Methods on Copy Number Variation and Genomic Stability of Human Induced Pluripotent Stem Cells

    OpenAIRE

    Kang, Xiangjin; Yu, Qian; Huang, Yuling; Song, Bing; Chen, Yaoyong; Gao, Xingcheng; He, Wenyin; Sun, Xiaofang; Fan, Yong

    2015-01-01

    Human-induced pluripotent stem cells (iPSCs) are derived from differentiated somatic cells using defined factors and provide a renewable source of autologous cells for cell therapy. Many reprogramming methods have been employed to generate human iPSCs, including the use of integrating vectors and non-integrating vectors. Maintenance of the genomic integrity of iPSCs is highly desirable if the cells are to be used in clinical applications. Here, using the Affymetrix Cytoscan HD array, we inves...

  3. Buoyancy effect on heat transfer in rotating smooth square U-duct at high rotation number

    Directory of Open Access Journals (Sweden)

    Yang Li

    2014-09-01

    Full Text Available The buoyancy effect on heat transfer in a rotating, two-pass, square channel is experimentally investigated in current work. The classical copper plate technique is performed to measure the regional averaged heat transfer coefficients. In order to perform a fundamental research, all turbulators are removed away. Two approaches of altering Buoyancy numbers are selected: varying rotation number from 0 to 2.08 at Reynolds number ranges of 10000 to 70000, and varying inlet density ratio from 0.07 to 0.16 at Reynolds number of 10000. And thus, Buoyancy numbers range from 0 to 12.9 for both cases. According to the experimental results, the relationships between heat transfer and Buoyancy numbers are in accord with those obtained under different rotation numbers. For both leading and trailing surface, a critical Buoyancy number exists for each X/D location. Before the critical point, the effect of Buoyancy number on heat transfer is limited; but after that, the Nusselt number ratios show different increase rate. Given the same rotation number, higher wall temperature ratios with its corresponding higher Buoyancy numbers substantially enhance heat transfer on both passages. And the critical exceed-point that heat transfer from trailing surface higher than leading surface happens at the same Buoyancy number for different wall temperature ratios in the second passage. Thus, the stronger buoyancy effect promotes heat transfer enhancement at high rotation number condition.

  4. Heat or mass transfer from a sphere in Stokes flow at low Péclet number

    KAUST Repository

    Bell, Christopher G.

    2013-04-01

    We consider the low Péclet number, Pe≪1, asymptotic solution for steady-state heat or mass transfer from a sphere immersed in Stokes flow with a Robin boundary condition on its surface, representing Newton cooling or a first-order chemical reaction. The application of Van Dyke\\'s rule up to terms of O(Pe3) shows that the O(Pe3logPe) terms in the expression for the average Nusselt/Sherwood number are twice those previously derived in the literature. Inclusion of the O(Pe3) terms is shown to increase the range of validity of the expansion. © 2012 Elsevier Ltd. All rights reserved.

  5. An alphavirus vector overcomes the presence of neutralizing antibodies and elevated numbers of Tregs to induce immune responses in humans with advanced cancer.

    Science.gov (United States)

    Morse, Michael A; Hobeika, Amy C; Osada, Takuya; Berglund, Peter; Hubby, Bolyn; Negri, Sarah; Niedzwiecki, Donna; Devi, Gayathri R; Burnett, Bruce K; Clay, Timothy M; Smith, Jonathan; Lyerly, H Kim

    2010-09-01

    Therapeutic anticancer vaccines are designed to boost patients' immune responses to tumors. One approach is to use a viral vector to deliver antigen to in situ DCs, which then activate tumor-specific T cell and antibody responses. However, vector-specific neutralizing antibodies and suppressive cell populations such as Tregs remain great challenges to the efficacy of this approach. We report here that an alphavirus vector, packaged in virus-like replicon particles (VRP) and capable of efficiently infecting DCs, could be repeatedly administered to patients with metastatic cancer expressing the tumor antigen carcinoembryonic antigen (CEA) and that it overcame high titers of neutralizing antibodies and elevated Treg levels to induce clinically relevant CEA-specific T cell and antibody responses. The CEA-specific antibodies mediated antibody-dependent cellular cytotoxicity against tumor cells from human colorectal cancer metastases. In addition, patients with CEA-specific T cell responses exhibited longer overall survival. These data suggest that VRP-based vectors can overcome the presence of neutralizing antibodies to break tolerance to self antigen and may be clinically useful for immunotherapy in the setting of tumor-induced immunosuppression.

  6. Influence Of The Number Of Platelets And Hemoglobin Concentrations In Predicting The Development Of Proteinuria Induced By The Administration Of Bevacizumab

    Directory of Open Access Journals (Sweden)

    Dabanovic Vera

    2015-06-01

    Full Text Available Bevacizumab neutralizes a key stimulation factor in tumour angiogenesis - vascular endothelial growth factor (VEGF. The origin of VEGF is related to platelets, and the basic stimulus for its production is hypoxia. By neutralizing VEGF, changes occur in the blood that are manifested at the platelet and haemoglobin levels. Study results indicate that proteinuria is a side effect of bevacizumab treatment. The aim of the present study was to examine the percentages of proteinuria in patients with metastatic colorectal cancer after the administration of bevacizumab. The correlation between the degree of proteinuria and changes in the number of platelets and concentration of haemoglobin in patients, as well as in relation to the age (< 60 i ≥ 60 and gender of the patients, was examined.

  7. Increasing fat content from 20 to 45 wt% in a complex diet induces lower endotoxemia in parallel with an increased number of intestinal goblet cells in mice.

    Science.gov (United States)

    Benoit, Bérengère; Laugerette, Fabienne; Plaisancié, Pascale; Géloën, Alain; Bodennec, Jacques; Estienne, Monique; Pineau, Gaëlle; Bernalier-Donadille, Annick; Vidal, Hubert; Michalski, Marie-Caroline

    2015-04-01

    The impacts of high-fat diets (HFDs) on the onset of metabolic endotoxemia and low-grade inflammation are well established in rodent models. However, the dose-effect of dietary lipid intakes on these parameters is not known. We hypothesized that increasing dietary lipid amounts could be linked to parallel increases of endotoxemia, low-grade inflammation, and metabolic and intestinal alterations. Six-week-old male C57BL/6J mice were fed a low-fat diet (LFD, 2.6 wt% of lipids), a moderate HFD (mHFD, 22 wt% of lipids), or a very HFD (vHFD, 45 wt% of lipids) formulated mainly using chow ingredients and milk fat. After 12 weeks, white adipose tissues, liver, intestine, distal colon contents, and plasma were collected. Only vHFD mice significantly increased body weight and fat mass vs LFD mice. This was associated with increases of plasma concentrations of triglycerides, leptin and adiponectin, and liver lipids. No such differences were observed between LFD and mHFD mice. However, mHFD developed metabolic endotoxemia and inflammation, unlike vHFD mice. In turn, vHFD mice showed more goblet cells in all intestine segments vs both other groups and a decrease of Bacteroides-Prevotella in their microbiota vs LFD mice. Finally, mHFD mice colon exhibited a decrease in lactobacilli and in the levels of occludin phosphorylation. Altogether, using complex HFD, no associations were observed between dietary lipid amounts and the magnitude of endotoxemia, inflammation, and physiological alterations developed. These results reveal the impact of the diet composition on intestinal goblet cells and mucus coat, bringing new insights about further consequences on HFD-induced metabolic disorders. Copyright © 2015 Elsevier Inc. All rights reserved.

  8. On the determination of plasma electron number density from Stark broadened hydrogen Balmer series lines in Laser-Induced Breakdown Spectroscopy experiments

    Energy Technology Data Exchange (ETDEWEB)

    Pardini, L., E-mail: loren.pard@gmail.com [Istituto di Chimica dei Composti Organometallici del CNR, Area della Ricerca del CNR di Pisa, Via G. Moruzzi 1, 56124 Pisa (Italy); Legnaioli, S.; Lorenzetti, G.; Palleschi, V. [Istituto di Chimica dei Composti Organometallici del CNR, Area della Ricerca del CNR di Pisa, Via G. Moruzzi 1, 56124 Pisa (Italy); Gaudiuso, R.; De Giacomo, A. [Dipartimento di Chimica, Università di Bari, Via Orabona 4, 70126 Bari (Italy); Diaz Pace, D.M. [Instituto de Física ‘Arroyo Seco’, Facultad de Ciencias Exactas, Paraje Arroyo Seco, B7000GHG Tandil (Argentina); Anabitarte Garcia, F. [Photonic Engineering Group, Universidad de Cantabria, Edificio I+D+iTelecomunicación, Dpto. TEISA, 39005 Santander (Spain); Holanda Cavalcanti, G. de [Institute of Physics, Universidade Federal Fluminense, UFF, Campus da Praia Vermelha, Av. Gal Milton Tavares de Souza, Gragoatá, 24310 240 Niterói, RJ (Brazil); Parigger, C. [University of Tennessee Space Institute, 411 B. H. Goethert Parkway, Tullahoma, TN 37388-9700 (United States)

    2013-10-01

    In this work, different theories for the determination of the electron density in Laser-Induced Breakdown Spectroscopy (LIBS) utilizing the emission lines belonging to the hydrogen Balmer series have been investigated. The plasmas were generated by a Nd:Yag laser (1064 nm) pulsed irradiation of pure hydrogen gas at a pressure of 2 · 10{sup 4} Pa. H{sub α}, Η{sub β}, Η{sub γ}, Η{sub δ}, and H{sub ε} Balmer lines were recorded at different delay times after the laser pulse. The plasma electron density was evaluated through the measurement of the Stark broadenings and the experimental results were compared with the predictions of three theories (the Standard Theory as developed by Kepple and Griem, the Advanced Generalized Theory by Oks et al., and the method discussed by Gigosos et al.) that are commonly employed for plasma diagnostics and that describe LIBS plasmas at different levels of approximations. A simple formula for pure hydrogen plasma in thermal equilibrium was also proposed to infer plasma electron density using the H{sub α} line. The results obtained showed that at high hydrogen concentration, the H{sub α} line is affected by considerable self-absorption. In this case, it is preferable to use the H{sub β} line for a reliable calculation of the electron density. - Highlights: • We evaluated the electron density in LIPs utilizing the hydrogen Balmer series. • Plasmas were generated by a Nd:Yag laser (1064 nm) on pure hydrogen gas. • We show that at high hydrogen concentration, H{sub b}eta line is preferable than H{sub a}lpha. • We propose a formula to derive the plasma electron density using the H{sub a}lpha line.

  9. Cilia walls influence on peristaltically induced motion of magneto-fluid through a porous medium at moderate Reynolds number: Numerical study

    Directory of Open Access Journals (Sweden)

    R.E. Abo-Elkhair

    2017-04-01

    Full Text Available This article addresses, effects of a magneto-fluid through a Darcy flow model with oscillatory wavy walled whose inner surface is ciliated. The equations that governing the flow are modeled without using any approximations. Adomian Decomposition Method (ADM is used to evaluate the solution of our system of nonlinear partial differential equations. Stream function, velocity and pressure gradient components are obtained by using the vorticity formula. The effects for our arbitrary physical parameters on flow characteristics are analyzed by plotting diagrams and discussed in details. With the help of stream lines the trapping mechanism has also been discussed. The major outcomes for the ciliated channel walls are: The axial velocity is higher without a ciliated walls than that for a ciliated walls and an opposite behaviour is shown near the ciliated channel walls. The pressure gradients in both directions are higher for a ciliated channel walls. More numbers of the trapped bolus in the absent of the eccentricity of the cilia elliptic path.

  10. Chronic but not acute virus infection induces sustained expansion of myeloid suppressor cell numbers that inhibit viral-specific T cell immunity.

    Science.gov (United States)

    Norris, Brian A; Uebelhoer, Luke S; Nakaya, Helder I; Price, Aryn A; Grakoui, Arash; Pulendran, Bali

    2013-02-21

    Resolution of acute and chronic viral infections requires activation of innate cells to initiate and maintain adaptive immune responses. Here we report that infection with acute Armstrong (ARM) or chronic Clone 13 (C13) strains of lymphocytic choriomeningitis virus (LCMV) led to two distinct phases of innate immune response. During the first 72 hr of infection, dendritic cells upregulated activation markers and stimulated antiviral CD8(+) T cells, independent of viral strain. Seven days after infection, there was an increase in Ly6C(hi) monocytic and Gr-1(hi) neutrophilic cells in lymphoid organs and blood. This expansion in cell numbers was enhanced and sustained in C13 infection, whereas it occurred only transiently with ARM infection. These cells resembled myeloid-derived suppressor cells and potently suppressed T cell proliferation. The reduction of monocytic cells in Ccr2(-/-) mice or after Gr-1 antibody depletion enhanced antiviral T cell function. Thus, innate cells have an important immunomodulatory role throughout chronic infection. Copyright © 2013 Elsevier Inc. All rights reserved.

  11. Effects of chromosomal breaks induced by X-irradiation on the number of mesosomes and the cytoplasmic organization of Streptococcus faecalis

    International Nuclear Information System (INIS)

    Parks, L.C.; Dicker, D.T.; Conger, A.D.; Daneo-Moore, L.; Higgins, M.L.

    1981-01-01

    A model which explains mesosome formation via a contraction of the cytoplasm and nucleoid when bacteria are physiologically disturbed was tested by 1) X-irradiation of unfixed cells of Streptococcus faecalis to produce chromosomal breaks and to remove DNA attached to the cell membrane; 2) subsequent determination of the number of irradiated cells in which mesosomes and central density changes could be visualised after fixative was added. The results obtained by exposure of cells to a) doses up to 1100 krads before fixation and b) doses greater than 1100 krads before fixation suggested that mesosomes are formed when localized sites on the cell membrane are pulled from close contact with the cell wall into the cytoplasm by the action of a cross-linking fixative via the aggregation of intracytoplasmic components such as DNA. This model considers the attachment of DNA and/or other cytoplasmic components to the membrane as an intrinsic part of its mechanism. The formation of central and peripheral mesosomes in unirradiated and X-irradiated cells are contrasted. (author)

  12. Kinetics behaviour of metastable equiatomic Cu–Fe solid solution as function of the number of collisions induced by mechanical alloying

    Energy Technology Data Exchange (ETDEWEB)

    Contini, A., E-mail: alessandro.contini@hotmail.com [Dipartimento di Chimica e Farmacia, Università degli Studi di Sassari, via Vienna 2, 07100 Sassari (Italy); Delogu, F. [Dipartimento di Ingegneria Meccanica, Chimica, e dei Materiali, Università degli Studi di Cagliari, via Marengo 2, 09123 Cagliari (Italy); Garroni, S.; Mulas, G.; Enzo, S. [Dipartimento di Chimica e Farmacia, Università degli Studi di Sassari, via Vienna 2, 07100 Sassari (Italy)

    2014-12-05

    Graphical abstract: - Highlights: • Cu–Fe powders were studied as a function of the number of hits during MA. • An impulsive model describes the kinetics curves of solid solution formation. • The kinetic curve indicates that powders must undergo 6 critical events to transform. - Abstract: We have addressed a new study by mechanical alloying on the nominally immiscible Cu{sub 50}Fe{sub 50} system with the aim of relating the solid state transformation process, with formation of a disordered unstable solid solution having the face centered cubic habit, to parameters reflecting the impulsive, discontinuous nature of the process. The milling set-up, tools and powder were adjusted in order to ensure completely anelastic hits. Phase analysis, structure and microstructure parameters of such powder system have been followed accurately in the course of the kinetics by X-ray Diffraction using the Rietveld method. The experimental kinetics data points of the amount of transformed solid solution show a typical sigmoidal behavior. It was assumed that dissolution only occurs in the volumes of material that have undergone the necessary critical loading conditions, which is accounted by a discrete series expansion. The mass fraction effectively processed at each collision can be regarded as an apparent rate constant for the microstructural refinement and phase transformation processes. Analysis of model curves fitting the experimental data suggests that it takes up an average of 6 impacts of coupled powder particles to drive the system to the new unstable nano-crystalline state.

  13. Number Sense on the Number Line

    Science.gov (United States)

    Woods, Dawn Marie; Ketterlin Geller, Leanne; Basaraba, Deni

    2018-01-01

    A strong foundation in early number concepts is critical for students' future success in mathematics. Research suggests that visual representations, like a number line, support students' development of number sense by helping them create a mental representation of the order and magnitude of numbers. In addition, explicitly sequencing instruction…

  14. Low energy fermion number violation

    International Nuclear Information System (INIS)

    Peccei, R.D.

    1989-01-01

    After a brief aside on charge quantization in the standard electroweak theory, I concentrate on various aspects of anomaly induced fermion number violation in the standard model. A critical analysis of the role of sphalerons for the universe's baryon asymmetry is presented and the importance of calculating directly fermion number violating Green's functions is stressed. A physical interpretation of the recent observation of Ringwald, that coherent effects in the electroweak theory lead to catastrophic fermion number violation at 100 TeV, is discussed. Possible quantum effects which might spoil this semi-classical picture are examined

  15. On the number of special numbers

    Indian Academy of Sciences (India)

    ... factorizaton for all exponents. Let V ( x ) be the number of special numbers ≤ x . We will prove that there is a constant c > 1 such that V ( x ) ∼ c x l o g x . We will make some remarks on determining the error term at the end. Using the explicit abc conjecture, we will study the existence of 23 consecutive special integers.

  16. Effects of Prandtl number on the laminar cross flow past a heated cylinder

    Science.gov (United States)

    Ajith Kumar, S.; Mathur, Manikandan; Sameen, A.; Anil Lal, S.

    2016-11-01

    Flow past a heated cylinder at constant surface temperature is computationally simulated and analyzed in the laminar regime at moderate buoyancy. The parameters governing the flow dynamics are the Reynolds number, Re, the Richardson number, Ri, and the Prandtl number, Pr. We perform our computations in the range 10 ≤ Re ≤ 35, for which the flow past an unheated cylinder results in a steady separation bubble, and vary the other two parameters in the range 0 ≤ Ri ≤ 2, 0.25 ≤ Pr ≤ 100. The heat transfer from the entire cylinder surface, quantified by the average Nusselt number Nuavg, is shown to obey Nuavg = 0.7435Re0.44Pr0.346 in the mixed convection regime we investigate. For a fixed Re and Pr, the flow downstream of the cylinder becomes asymmetric as Ri is increased from zero, followed by a complete disappearance of the vortices in the recirculation bubble beyond a threshold value of Ri. For a fixed Re and Ri, the vortices in the recirculation bubble are again observed to disappear beyond a threshold Pr, but with the reappearance of both the vortices above a larger threshold of Pr. In the limit of large Pr, the time-averaged flow outside the thermal boundary layer but within the near-wake region regains symmetry about the centerline and ultimately converges to a flow field similar to that of Ri = 0; in the far-wake region, however, we observe asymmetric vortex shedding for moderate Pr. The thermal plume structure in the cylinder wake is then discussed, and the plume generation is identified at points on the cylinder where the Nusselt number is a local minimum. The difference between the plume generation and the flow separation locations on the cylinder is shown to converge to zero in the limit of large Pr. We conclude by plotting the lift and drag coefficients as a function of Ri and Pr, observing that CD decreases with Ri for Pr Prt), where Prt ≈ 7.5.

  17. Number words and number symbols a cultural history of numbers

    CERN Document Server

    Menninger, Karl

    1992-01-01

    Classic study discusses number sequence and language and explores written numerals and computations in many cultures. "The historian of mathematics will find much to interest him here both in the contents and viewpoint, while the casual reader is likely to be intrigued by the author's superior narrative ability.

  18. Those fascinating numbers

    CERN Document Server

    Koninck, Jean-Marie De

    2009-01-01

    Who would have thought that listing the positive integers along with their most remarkable properties could end up being such an engaging and stimulating adventure? The author uses this approach to explore elementary and advanced topics in classical number theory. A large variety of numbers are contemplated: Fermat numbers, Mersenne primes, powerful numbers, sublime numbers, Wieferich primes, insolite numbers, Sastry numbers, voracious numbers, to name only a few. The author also presents short proofs of miscellaneous results and constantly challenges the reader with a variety of old and new n

  19. Introduction to number theory

    CERN Document Server

    Vazzana, Anthony; Garth, David

    2007-01-01

    One of the oldest branches of mathematics, number theory is a vast field devoted to studying the properties of whole numbers. Offering a flexible format for a one- or two-semester course, Introduction to Number Theory uses worked examples, numerous exercises, and two popular software packages to describe a diverse array of number theory topics.

  20. Building Numbers from Primes

    Science.gov (United States)

    Burkhart, Jerry

    2009-01-01

    Prime numbers are often described as the "building blocks" of natural numbers. This article shows how the author and his students took this idea literally by using prime factorizations to build numbers with blocks. In this activity, students explore many concepts of number theory, including the relationship between greatest common factors and…

  1. Algebraic number theory

    CERN Document Server

    Jarvis, Frazer

    2014-01-01

    The technical difficulties of algebraic number theory often make this subject appear difficult to beginners. This undergraduate textbook provides a welcome solution to these problems as it provides an approachable and thorough introduction to the topic. Algebraic Number Theory takes the reader from unique factorisation in the integers through to the modern-day number field sieve. The first few chapters consider the importance of arithmetic in fields larger than the rational numbers. Whilst some results generalise well, the unique factorisation of the integers in these more general number fields often fail. Algebraic number theory aims to overcome this problem. Most examples are taken from quadratic fields, for which calculations are easy to perform. The middle section considers more general theory and results for number fields, and the book concludes with some topics which are more likely to be suitable for advanced students, namely, the analytic class number formula and the number field sieve. This is the fi...

  2. p-adic numbers

    OpenAIRE

    Grešak, Rozalija

    2015-01-01

    The field of real numbers is usually constructed using Dedekind cuts. In these thesis we focus on the construction of the field of real numbers using metric completion of rational numbers using Cauchy sequences. In a similar manner we construct the field of p-adic numbers, describe some of their basic and topological properties. We follow by a construction of complex p-adic numbers and we compare them with the ordinary complex numbers. We conclude the thesis by giving a motivation for the int...

  3. On the number of special numbers

    Indian Academy of Sciences (India)

    We now apply the theory of the Thue equation to obtain an effective bound on m. Indeed, by Lemma 3.2, we can write m2 = ba3 and m2 − 4 = cd3 with b, c cubefree. By the above, both b, c are bounded since they are cubefree and all their prime factors are less than e63727. Now we have a finite number of. Thue equations:.

  4. Hawaiian Number Systems.

    Science.gov (United States)

    Hughes, Barnabas

    1982-01-01

    The history of Hawaiian number systems is examined, and answers to questions regarding Hawaiian number words, including their origin and factors that influenced their development, are covered. A brief guide for pronouncing Hawaiian words is also provided. (MP)

  5. Making decisions from numbers

    Energy Technology Data Exchange (ETDEWEB)

    Somers, E.

    1987-03-01

    Regulatory agencies require numbers to provide health protection. The manner in which these numbers are derived from animal experiments and human epidemiology is considered together with the limitations and inadequacies of these numbers. Some recent examples of risk assessment in Canada are given including asbestos, drinking water, and indoor air quality. The value of these numbers in providing a measure of the hazard in a wider perspective is stressed, although they can never be the sole determinant of public policy.

  6. Analytic number theory

    CERN Document Server

    Matsumoto, Kohji

    2002-01-01

    The book includes several survey articles on prime numbers, divisor problems, and Diophantine equations, as well as research papers on various aspects of analytic number theory such as additive problems, Diophantine approximations and the theory of zeta and L-function Audience Researchers and graduate students interested in recent development of number theory

  7. Safety-in-numbers

    DEFF Research Database (Denmark)

    Elvik, Rune; Bjørnskau, Torkel

    2017-01-01

    Highlights •26 studies of the safety-in-numbers effect are reviewed. •The existence of a safety-in-numbers effect is confirmed. •Results are consistent. •Causes of the safety-in-numbers effect are incompletely known....

  8. Asymptotic numbers: Pt.1

    International Nuclear Information System (INIS)

    Todorov, T.D.

    1980-01-01

    The set of asymptotic numbers A as a system of generalized numbers including the system of real numbers R, as well as infinitely small (infinitesimals) and infinitely large numbers, is introduced. The detailed algebraic properties of A, which are unusual as compared with the known algebraic structures, are studied. It is proved that the set of asymptotic numbers A cannot be isomorphically embedded as a subspace in any group, ring or field, but some particular subsets of asymptotic numbers are shown to be groups, rings, and fields. The algebraic operation, additive and multiplicative forms, and the algebraic properties are constructed in an appropriate way. It is shown that the asymptotic numbers give rise to a new type of generalized functions quite analogous to the distributions of Schwartz allowing, however, the operation multiplication. A possible application of these functions to quantum theory is discussed

  9. Applied number theory

    CERN Document Server

    Niederreiter, Harald

    2015-01-01

    This textbook effectively builds a bridge from basic number theory to recent advances in applied number theory. It presents the first unified account of the four major areas of application where number theory plays a fundamental role, namely cryptography, coding theory, quasi-Monte Carlo methods, and pseudorandom number generation, allowing the authors to delineate the manifold links and interrelations between these areas.  Number theory, which Carl-Friedrich Gauss famously dubbed the queen of mathematics, has always been considered a very beautiful field of mathematics, producing lovely results and elegant proofs. While only very few real-life applications were known in the past, today number theory can be found in everyday life: in supermarket bar code scanners, in our cars’ GPS systems, in online banking, etc.  Starting with a brief introductory course on number theory in Chapter 1, which makes the book more accessible for undergraduates, the authors describe the four main application areas in Chapters...

  10. Energetics and dynamics of droplet evaporation in high temperature intermediate Reynolds number flows

    Science.gov (United States)

    Renksizbulut, M.

    Nusselt Numbers and drag coefficients of single-component liquid droplets and solid spheres in high temperature, intermediate Reynolds Number flows were investigated. The evaporation of suspended water, Methanol and n-Heptane droplets were followed in laminar air streams up to 1059 K in temperature using a steady-state measurement technique. It is found that the dynamic blowing effect of evaporation causes large reductions in heat transfer rates, and that the film conditions constitute an appropriate reference state for the evaluation of thermophysical properties. The numerical results indicate that the blowing effect of evaporation on momentum transfer is to reduce friction drag very significantly but at the same time increase pressure drag by almost an equal amount; the net effect on the total drag force being only a marginal reduction. In all cases, it is found that thermophysical property variations play a very dominant role in reducing the drag forces acting on cold particles. Results are analysed and a correlation for stagnation-point heat transfer is also presented.

  11. Invitation to number theory

    CERN Document Server

    Ore, Oystein

    2017-01-01

    Number theory is the branch of mathematics concerned with the counting numbers, 1, 2, 3, … and their multiples and factors. Of particular importance are odd and even numbers, squares and cubes, and prime numbers. But in spite of their simplicity, you will meet a multitude of topics in this book: magic squares, cryptarithms, finding the day of the week for a given date, constructing regular polygons, pythagorean triples, and many more. In this revised edition, John Watkins and Robin Wilson have updated the text to bring it in line with contemporary developments. They have added new material on Fermat's Last Theorem, the role of computers in number theory, and the use of number theory in cryptography, and have made numerous minor changes in the presentation and layout of the text and the exercises.

  12. Predicting Lotto Numbers

    DEFF Research Database (Denmark)

    Jørgensen, Claus Bjørn; Suetens, Sigrid; Tyran, Jean-Robert

    numbers based on recent drawings. While most players pick the same set of numbers week after week without regards of numbers drawn or anything else, we find that those who do change, act on average in the way predicted by the law of small numbers as formalized in recent behavioral theory. In particular......We investigate the “law of small numbers” using a unique panel data set on lotto gambling. Because we can track individual players over time, we can measure how they react to outcomes of recent lotto drawings. We can therefore test whether they behave as if they believe they can predict lotto......, on average they move away from numbers that have recently been drawn, as suggested by the “gambler’s fallacy”, and move toward numbers that are on streak, i.e. have been drawn several weeks in a row, consistent with the “hot hand fallacy”....

  13. The simple complex numbers

    OpenAIRE

    Zalesny, Jaroslaw

    2008-01-01

    A new simple geometrical interpretation of complex numbers is presented. It differs from their usual interpretation as points in the complex plane. From the new point of view the complex numbers are rather operations on vectors than points. Moreover, in this approach the real, imaginary and complex numbers have similar interpretation. They are simply some operations on vectors. The presented interpretation is simpler, more natural, and better adjusted to possible applications in geometry and ...

  14. Predicting Lotto Numbers

    DEFF Research Database (Denmark)

    Suetens, Sigrid; Galbo-Jørgensen, Claus B.; Tyran, Jean-Robert Karl

    2016-01-01

    as formalized in recent behavioral theory. In particular, players tend to bet less on numbers that have been drawn in the preceding week, as suggested by the ‘gambler’s fallacy’, and bet more on a number if it was frequently drawn in the recent past, consistent with the ‘hot-hand fallacy’.......We investigate the ‘law of small numbers’ using a data set on lotto gambling that allows us to measure players’ reactions to draws. While most players pick the same set of numbers week after week, we find that those who do change react on average as predicted by the law of small numbers...

  15. Intuitive numbers guide decisions

    Directory of Open Access Journals (Sweden)

    Ellen Peters

    2008-12-01

    Full Text Available Measuring reaction times to number comparisons is thought to reveal a processing stage in elementary numerical cognition linked to internal, imprecise representations of number magnitudes. These intuitive representations of the mental number line have been demonstrated across species and human development but have been little explored in decision making. This paper develops and tests hypotheses about the influence of such evolutionarily ancient, intuitive numbers on human decisions. We demonstrate that individuals with more precise mental-number-line representations are higher in numeracy (number skills consistent with previous research with children. Individuals with more precise representations (compared to those with less precise representations also were more likely to choose larger, later amounts over smaller, immediate amounts, particularly with a larger proportional difference between the two monetary outcomes. In addition, they were more likely to choose an option with a larger proportional but smaller absolute difference compared to those with less precise representations. These results are consistent with intuitive number representations underlying: a perceived differences between numbers, b the extent to which proportional differences are weighed in decisions, and, ultimately, c the valuation of decision options. Human decision processes involving numbers important to health and financial matters may be rooted in elementary, biological processes shared with other species.

  16. Beurling generalized numbers

    CERN Document Server

    Diamond, Harold G; Cheung, Man Ping

    2016-01-01

    "Generalized numbers" is a multiplicative structure introduced by A. Beurling to study how independent prime number theory is from the additivity of the natural numbers. The results and techniques of this theory apply to other systems having the character of prime numbers and integers; for example, it is used in the study of the prime number theorem (PNT) for ideals of algebraic number fields. Using both analytic and elementary methods, this book presents many old and new theorems, including several of the authors' results, and many examples of extremal behavior of g-number systems. Also, the authors give detailed accounts of the L^2 PNT theorem of J. P. Kahane and of the example created with H. L. Montgomery, showing that additive structure is needed for proving the Riemann hypothesis. Other interesting topics discussed are propositions "equivalent" to the PNT, the role of multiplicative convolution and Chebyshev's prime number formula for g-numbers, and how Beurling theory provides an interpretation of the ...

  17. Numbers, sequences and series

    CERN Document Server

    Hirst, Keith

    1994-01-01

    Number and geometry are the foundations upon which mathematics has been built over some 3000 years. This book is concerned with the logical foundations of number systems from integers to complex numbers. The author has chosen to develop the ideas by illustrating the techniques used throughout mathematics rather than using a self-contained logical treatise. The idea of proof has been emphasised, as has the illustration of concepts from a graphical, numerical and algebraic point of view. Having laid the foundations of the number system, the author has then turned to the analysis of infinite proc

  18. The adventure of numbers

    CERN Document Server

    Godefroy, Gilles

    2004-01-01

    Numbers are fascinating. The fascination begins in childhood, when we first learn to count. It continues as we learn arithmetic, algebra, geometry, and so on. Eventually, we learn that numbers not only help us to measure the world, but also to understand it and, to some extent, to control it. In The Adventure of Numbers, Gilles Godefroy follows the thread of our expanding understanding of numbers to lead us through the history of mathematics. His goal is to share the joy of discovering and understanding this great adventure of the mind. The development of mathematics has been punctuated by a n

  19. The Class Number Problem

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 3; Issue 7. The Class Number Problem - An Introduction to Algebraic Number Theory. Rajat Tandon. General ... Author Affiliations. Rajat Tandon1. Department of Mathematics, University of Hyderabad, Central University P.O., Hyderabad 500 046, India ...

  20. The Class Number Problem

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 3; Issue 7. The Class Number Problem - An Introduction to Algebraic Number Theory. Rajat Tandon. General Article Volume 3 Issue 7 July 1998 pp 28-37. Fulltext. Click here to view fulltext PDF. Permanent link:

  1. The Class Number Problem

    Indian Academy of Sciences (India)

    The Class Number Problem. 2. An Introduction to Algebraic Number Theory. Rajat Tandon received his PhD from Yale. University, USA. After an initial period as a visiting post-doctoral fellow at. TIFR, he joined the faculty of the North. Eastern Hill University, where he taught for a few years. For about two decades now, he ...

  2. A Numbers Game

    DEFF Research Database (Denmark)

    Levin, Bruce R; McCall, Ingrid C.; Perrot, Veronique

    2017-01-01

    We postulate that the inhibition of growth and low rates of mortality of bacteria exposed to ribosome-binding antibiotics deemed bacteriostatic can be attributed almost uniquely to these drugs reducing the number of ribosomes contributing to protein synthesis, i.e., the number of effective riboso...

  3. The Congruent Number Problem

    Indian Academy of Sciences (India)

    Given a positive integer n, is there a simple criterion which enables us to decide whether or not n is congruent? A few remarks are in order. To start with, if we ..... In other words 1 is a congruent number. Combining Propositions 2 and 3 with the fact that 1 is a non-congruent number, we deduce Fermat's last theorem for n=4.

  4. Templates, Numbers & Watercolors.

    Science.gov (United States)

    Clemesha, David J.

    1990-01-01

    Describes how a second-grade class used large templates to draw and paint five-digit numbers. The lesson integrated artistic knowledge and vocabulary with their mathematics lesson in place value. Students learned how draftspeople use templates, and they studied number paintings by Charles Demuth and Jasper Johns. (KM)

  5. Elementary number theory

    CERN Document Server

    Dudley, Underwood

    2008-01-01

    Ideal for a first course in number theory, this lively, engaging text requires only a familiarity with elementary algebra and the properties of real numbers. Author Underwood Dudley, who has written a series of popular mathematics books, maintains that the best way to learn mathematics is by solving problems. In keeping with this philosophy, the text includes nearly 1,000 exercises and problems-some computational and some classical, many original, and some with complete solutions. The opening chapters offer sound explanations of the basics of elementary number theory and develop the fundamenta

  6. Numbers and computers

    CERN Document Server

    Kneusel, Ronald T

    2015-01-01

    This is a book about numbers and how those numbers are represented in and operated on by computers. It is crucial that developers understand this area because the numerical operations allowed by computers, and the limitations of those operations, especially in the area of floating point math, affect virtually everything people try to do with computers. This book aims to fill this gap by exploring, in sufficient but not overwhelming detail, just what it is that computers do with numbers. Divided into two parts, the first deals with standard representations of integers and floating point numb

  7. On powerful numbers

    Directory of Open Access Journals (Sweden)

    R. A. Mollin

    1986-01-01

    Full Text Available A powerful number is a positive integer n satisfying the property that p2 divides n whenever the prime p divides n; i.e., in the canonical prime decomposition of n, no prime appears with exponent 1. In [1], S.W. Golomb introduced and studied such numbers. In particular, he asked whether (25,27 is the only pair of consecutive odd powerful numbers. This question was settled in [2] by W.A. Sentance who gave necessary and sufficient conditions for the existence of such pairs. The first result of this paper is to provide a generalization of Sentance's result by giving necessary and sufficient conditions for the existence of pairs of powerful numbers spaced evenly apart. This result leads us naturally to consider integers which are representable as a proper difference of two powerful numbers, i.e. n=p1−p2 where p1 and p2 are powerful numbers with g.c.d. (p1,p2=1. Golomb (op.cit. conjectured that 6 is not a proper difference of two powerful numbers, and that there are infinitely many numbers which cannot be represented as a proper difference of two powerful numbers. The antithesis of this conjecture was proved by W.L. McDaniel [3] who verified that every non-zero integer is in fact a proper difference of two powerful numbers in infinitely many ways. McDaniel's proof is essentially an existence proof. The second result of this paper is a simpler proof of McDaniel's result as well as an effective algorithm (in the proof for explicitly determining infinitely many such representations. However, in both our proof and McDaniel's proof one of the powerful numbers is almost always a perfect square (namely one is always a perfect square when n≢2(mod4. We provide in §2 a proof that all even integers are representable in infinitely many ways as a proper nonsquare difference; i.e., proper difference of two powerful numbers neither of which is a perfect square. This, in conjunction with the odd case in [4], shows that every integer is representable in

  8. Algebraic number theory

    CERN Document Server

    Weiss, Edwin

    1998-01-01

    Careful organization and clear, detailed proofs characterize this methodical, self-contained exposition of basic results of classical algebraic number theory from a relatively modem point of view. This volume presents most of the number-theoretic prerequisites for a study of either class field theory (as formulated by Artin and Tate) or the contemporary treatment of analytical questions (as found, for example, in Tate's thesis).Although concerned exclusively with algebraic number fields, this treatment features axiomatic formulations with a considerable range of applications. Modem abstract te

  9. Brief history of numbers

    CERN Document Server

    Corry, Leo

    2015-01-01

    The world around us is saturated with numbers. They are a fundamental pillar of our modern society, and accepted and used with hardly a second thought. But how did this state of affairs come to be? In this book, Leo Corry tells the story behind the idea of number from the early days of the Pythagoreans, up until the turn of the twentieth century. He presents an overview of how numbers were handled and conceived in classical Greek mathematics, in the mathematics of Islam, in European mathematics of the middle ages and the Renaissance, during the scientific revolution, all the way through to the

  10. Fundamentals of number theory

    CERN Document Server

    LeVeque, William J

    1996-01-01

    This excellent textbook introduces the basics of number theory, incorporating the language of abstract algebra. A knowledge of such algebraic concepts as group, ring, field, and domain is not assumed, however; all terms are defined and examples are given - making the book self-contained in this respect.The author begins with an introductory chapter on number theory and its early history. Subsequent chapters deal with unique factorization and the GCD, quadratic residues, number-theoretic functions and the distribution of primes, sums of squares, quadratic equations and quadratic fields, diopha

  11. Advanced number theory

    CERN Document Server

    Cohn, Harvey

    1980-01-01

    ""A very stimulating book ... in a class by itself."" - American Mathematical MonthlyAdvanced students, mathematicians and number theorists will welcome this stimulating treatment of advanced number theory, which approaches the complex topic of algebraic number theory from a historical standpoint, taking pains to show the reader how concepts, definitions and theories have evolved during the last two centuries. Moreover, the book abounds with numerical examples and more concrete, specific theorems than are found in most contemporary treatments of the subject.The book is divided into three parts

  12. Professor Stewart's incredible numbers

    CERN Document Server

    Stewart, Ian

    2015-01-01

    Ian Stewart explores the astonishing properties of numbers from 1 to10 to zero and infinity, including one figure that, if you wrote it out, would span the universe. He looks at every kind of number you can think of - real, imaginary, rational, irrational, positive and negative - along with several you might have thought you couldn't think of. He explains the insights of the ancient mathematicians, shows how numbers have evolved through the ages, and reveals the way numerical theory enables everyday life. Under Professor Stewart's guidance you will discover the mathematics of codes,

  13. Random number generation

    International Nuclear Information System (INIS)

    Coveyou, R.R.

    1974-01-01

    The subject of random number generation is currently controversial. Differing opinions on this subject seem to stem from implicit or explicit differences in philosophy; in particular, from differing ideas concerning the role of probability in the real world of physical processes, electronic computers, and Monte Carlo calculations. An attempt is made here to reconcile these views. The role of stochastic ideas in mathematical models is discussed. In illustration of these ideas, a mathematical model of the use of random number generators in Monte Carlo calculations is constructed. This model is used to set up criteria for the comparison and evaluation of random number generators. (U.S.)

  14. The emergence of number

    CERN Document Server

    Crossley, John N

    1987-01-01

    This book presents detailed studies of the development of three kinds of number. In the first part the development of the natural numbers from Stone-Age times right up to the present day is examined not only from the point of view of pure history but also taking into account archaeological, anthropological and linguistic evidence. The dramatic change caused by the introduction of logical theories of number in the 19th century is also treated and this part ends with a non-technical account of the very latest developments in the area of Gödel's theorem. The second part is concerned with the deve

  15. Supersymmetric Displaced Number States

    Directory of Open Access Journals (Sweden)

    Fredy R. Zypman

    2015-06-01

    Full Text Available We introduce, generate and study a family of supersymmetric displaced number states (SDNS that can be considered generalized coherent states of the supersymmetric harmonic oscillator. The family is created from the seminal supersymmetric boson-fermion entangling annihilation operator introduced by Aragone and Zypman and later expanded by Kornbluth and Zypman. Using the momentum representation, the states are obtained analytically in compact form as displaced supersymmetric number states. We study their position-momentum uncertainties, and their bunchiness by classifying them according to their Mandel Q-parameter in phase space. We were also able to find closed form analytical representations in the space and number basis.

  16. Number 1, January

    Indian Academy of Sciences (India)

    analog resonances in medium and heavy mass nuclei . . . . . . . . . . D I Salamov,. T Babacan, A Küc.ükbursa, S ¨Unlü and ˙I Maras. 1105. Study of photon-induced L3 vacancy alignment for elements La to U . . . . . . . ................................. Ajay Sharma, Meenu Singh and Raj Mittal. 1111. Electron impact single ionization of mono- ...

  17. Number 1, January

    Indian Academy of Sciences (India)

    The effect of instanton-induced interaction on P-wave meson spectra in con- stituent quark model . ... I Mehrotra and S Prakash. 101 π−-12C elastic scattering above the ∆ resonance using diffraction model . ..... and H A Cerdeira. 1143. Emergent organization of oscillator clusters in coupled self-regulatory chaotic maps .

  18. High Reynolds Number Turbulence

    National Research Council Canada - National Science Library

    Smits, Alexander J

    2007-01-01

    The objectives of the grant were to provide a systematic study to fill the gap between existing research on low Reynolds number turbulent flows to the kinds of turbulent flows encountered on full-scale vehicles...

  19. Really big numbers

    CERN Document Server

    Schwartz, Richard Evan

    2014-01-01

    In the American Mathematical Society's first-ever book for kids (and kids at heart), mathematician and author Richard Evan Schwartz leads math lovers of all ages on an innovative and strikingly illustrated journey through the infinite number system. By means of engaging, imaginative visuals and endearing narration, Schwartz manages the monumental task of presenting the complex concept of Big Numbers in fresh and relatable ways. The book begins with small, easily observable numbers before building up to truly gigantic ones, like a nonillion, a tredecillion, a googol, and even ones too huge for names! Any person, regardless of age, can benefit from reading this book. Readers will find themselves returning to its pages for a very long time, perpetually learning from and growing with the narrative as their knowledge deepens. Really Big Numbers is a wonderful enrichment for any math education program and is enthusiastically recommended to every teacher, parent and grandparent, student, child, or other individual i...

  20. Solar Indices - Sunspot Numbers

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Collection includes a variety of indices related to solar activity contributed by a number of national and private solar observatories located worldwide. This...

  1. Volume 9 Number 2

    African Journals Online (AJOL)

    OLUWOLE

    Table 1: Insect Invaders Encountered and their Stages at Collection from Decaying. Banana / Plantain Pseudo stems. Insect Order. Family. Genus. Species. Life Stage Encountered. Number (%). Coleoptera. Curculionidae Curculionidae. Curculionidae Curculionidae. Curculionidae Curculionidae. Curculionidae.

  2. Quantum random number generator

    Science.gov (United States)

    Pooser, Raphael C.

    2016-05-10

    A quantum random number generator (QRNG) and a photon generator for a QRNG are provided. The photon generator may be operated in a spontaneous mode below a lasing threshold to emit photons. Photons emitted from the photon generator may have at least one random characteristic, which may be monitored by the QRNG to generate a random number. In one embodiment, the photon generator may include a photon emitter and an amplifier coupled to the photon emitter. The amplifier may enable the photon generator to be used in the QRNG without introducing significant bias in the random number and may enable multiplexing of multiple random numbers. The amplifier may also desensitize the photon generator to fluctuations in power supplied thereto while operating in the spontaneous mode. In one embodiment, the photon emitter and amplifier may be a tapered diode amplifier.

  3. Drawing a random number

    DEFF Research Database (Denmark)

    Wanscher, Jørgen Bundgaard; Sørensen, Majken Vildrik

    2006-01-01

    Random numbers are used for a great variety of applications in almost any field of computer and economic sciences today. Examples ranges from stock market forecasting in economics, through stochastic traffic modelling in operations research to photon and ray tracing in graphics. The construction...... of a model or a solution method requires certain characteristics of the random numbers used. This is usually a distribution classification, which the sequence of random numbers must fulfill; of these some are very hard to fulfill and others are next to impossible. Today mathematics allows us to transform...... highly uniform multidimensional draws, which are highly relevant for todays traffic models. This paper shows among others combined shuffling and scrambling seems needless, that scrambling gives the lowest correlation and that there are detectable differences between random numbers, dependent...

  4. Report number codes

    International Nuclear Information System (INIS)

    Nelson, R.N.

    1985-05-01

    This publication lists all report number codes processed by the Office of Scientific and Technical Information. The report codes are substantially based on the American National Standards Institute, Standard Technical Report Number (STRN)-Format and Creation Z39.23-1983. The Standard Technical Report Number (STRN) provides one of the primary methods of identifying a specific technical report. The STRN consists of two parts: The report code and the sequential number. The report code identifies the issuing organization, a specific program, or a type of document. The sequential number, which is assigned in sequence by each report issuing entity, is not included in this publication. Part I of this compilation is alphabetized by report codes followed by issuing installations. Part II lists the issuing organization followed by the assigned report code(s). In both Parts I and II, the names of issuing organizations appear for the most part in the form used at the time the reports were issued. However, for some of the more prolific installations which have had name changes, all entries have been merged under the current name

  5. Report number codes

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, R.N. (ed.)

    1985-05-01

    This publication lists all report number codes processed by the Office of Scientific and Technical Information. The report codes are substantially based on the American National Standards Institute, Standard Technical Report Number (STRN)-Format and Creation Z39.23-1983. The Standard Technical Report Number (STRN) provides one of the primary methods of identifying a specific technical report. The STRN consists of two parts: The report code and the sequential number. The report code identifies the issuing organization, a specific program, or a type of document. The sequential number, which is assigned in sequence by each report issuing entity, is not included in this publication. Part I of this compilation is alphabetized by report codes followed by issuing installations. Part II lists the issuing organization followed by the assigned report code(s). In both Parts I and II, the names of issuing organizations appear for the most part in the form used at the time the reports were issued. However, for some of the more prolific installations which have had name changes, all entries have been merged under the current name.

  6. The LHC in numbers

    CERN Multimedia

    Alizée Dauvergne

    2010-01-01

    What makes the LHC the biggest particle accelerator in the world? Here are some of the numbers that characterise the LHC, and their equivalents in terms that are easier for us to imagine.   Feature Number Equivalent Circumference ~ 27 km   Distance covered by beam in 10 hours ~ 10 billion km a round trip to Neptune Number of times a single proton travels around the ring each second 11 245   Speed of protons first entering the LHC 299 732 500 m/s 99.9998 % of the speed of light Speed of protons when they collide 299 789 760 m/s 99.9999991 % of the speed of light Collision temperature ~ 1016 °C ove...

  7. Chromosome numbers in Bromeliaceae

    Directory of Open Access Journals (Sweden)

    Cotias-de-Oliveira Ana Lúcia Pires

    2000-01-01

    Full Text Available The present study reports chromosome numbers of 17 species of Bromeliaceae, belonging to the genera Encholirium, Bromelia, Orthophytum, Hohenbergia, Billbergia, Neoglaziovia, Aechmea, Cryptanthus and Ananas. Most species present 2n = 50, however, Bromelia laciniosa, Orthophytum burle-marxii and O. maracasense are polyploids with 2n = 150, 2n = 100 and 2n = 150, respectively, while for Cryptanthus bahianus, 2n = 34 + 1-4B. B chromosomes were observed in Bromelia plumieri and Hohenbergia aff. utriculosa. The chromosome number of all species was determined for the first time, except for Billbergia chlorosticta and Cryptanthus bahianus. Our data supports the hypothesis of a basic number of x = 25 for the Bromeliaceae family and decreasing aneuploidy in the genus Cryptanthus.

  8. Quantum random number generator

    Science.gov (United States)

    Soubusta, Jan; Haderka, Ondrej; Hendrych, Martin

    2001-03-01

    Since reflection or transmission of a quantum particle on a beamsplitter is inherently random quantum process, a device built on this principle does not suffer from drawbacks of neither pseudo-random computer generators or classical noise sources. Nevertheless, a number of physical conditions necessary for high quality random numbers generation must be satisfied. Luckily, in quantum optics realization they can be well controlled. We present an easy random number generator based on the division of weak light pulses on a beamsplitter. The randomness of the generated bit stream is supported by passing the data through series of 15 statistical test. The device generates at a rate of 109.7 kbit/s.

  9. CONFUSION WITH TELEPHONE NUMBERS

    CERN Multimedia

    Telecom Service

    2002-01-01

    The area code is now required for all telephone calls within Switzerland. Unfortunately this is causing some confusion. CERN has received complaints that incoming calls intended for CERN mobile phones are being directed to private subscribers. This is caused by mistakenly dialing the WRONG code (e.g. 022) in front of the mobile number. In order to avoid these problems, please inform your correspondents that the correct numbers are: 079 201 XXXX from Switzerland; 0041 79 201 XXXX from other countries. Telecom Service  

  10. CONFUSION WITH TELEPHONE NUMBERS

    CERN Multimedia

    Telecom Service

    2002-01-01

    he area code is now required for all telephone calls within Switzerland. Unfortunately this is causing some confusion. CERN has received complaints that incoming calls intended for CERN mobile phones are being directed to private subscribers. This is caused by mistakenly dialing the WRONG code (e.g. 022) in front of the mobile number. In order to avoid these problems, please inform your correspondents that the correct numbers are: 079 201 XXXX from Switzerland; 0041 79 201 XXXX from other countries. Telecom Service

  11. Analytic number theory

    CERN Document Server

    Iwaniec, Henryk

    2004-01-01

    Analytic Number Theory distinguishes itself by the variety of tools it uses to establish results, many of which belong to the mainstream of arithmetic. One of the main attractions of analytic number theory is the vast diversity of concepts and methods it includes. The main goal of the book is to show the scope of the theory, both in classical and modern directions, and to exhibit its wealth and prospects, its beautiful theorems and powerful techniques. The book is written with graduate students in mind, and the authors tried to balance between clarity, completeness, and generality. The exercis

  12. Geometry of numbers

    CERN Document Server

    Gruber, Peter M

    1987-01-01

    This volume contains a fairly complete picture of the geometry of numbers, including relations to other branches of mathematics such as analytic number theory, diophantine approximation, coding and numerical analysis. It deals with convex or non-convex bodies and lattices in euclidean space, etc.This second edition was prepared jointly by P.M. Gruber and the author of the first edition. The authors have retained the existing text (with minor corrections) while adding to each chapter supplementary sections on the more recent developments. While this method may have drawbacks, it has the definit

  13. Algebraic theory of numbers

    CERN Document Server

    Samuel, Pierre

    2008-01-01

    Algebraic number theory introduces students not only to new algebraic notions but also to related concepts: groups, rings, fields, ideals, quotient rings and quotient fields, homomorphisms and isomorphisms, modules, and vector spaces. Author Pierre Samuel notes that students benefit from their studies of algebraic number theory by encountering many concepts fundamental to other branches of mathematics - algebraic geometry, in particular.This book assumes a knowledge of basic algebra but supplements its teachings with brief, clear explanations of integrality, algebraic extensions of fields, Gal

  14. Earthquake number forecasts testing

    Science.gov (United States)

    Kagan, Yan Y.

    2017-10-01

    We study the distributions of earthquake numbers in two global earthquake catalogues: Global Centroid-Moment Tensor and Preliminary Determinations of Epicenters. The properties of these distributions are especially required to develop the number test for our forecasts of future seismic activity rate, tested by the Collaboratory for Study of Earthquake Predictability (CSEP). A common assumption, as used in the CSEP tests, is that the numbers are described by the Poisson distribution. It is clear, however, that the Poisson assumption for the earthquake number distribution is incorrect, especially for the catalogues with a lower magnitude threshold. In contrast to the one-parameter Poisson distribution so widely used to describe earthquake occurrences, the negative-binomial distribution (NBD) has two parameters. The second parameter can be used to characterize the clustering or overdispersion of a process. We also introduce and study a more complex three-parameter beta negative-binomial distribution. We investigate the dependence of parameters for both Poisson and NBD distributions on the catalogue magnitude threshold and on temporal subdivision of catalogue duration. First, we study whether the Poisson law can be statistically rejected for various catalogue subdivisions. We find that for most cases of interest, the Poisson distribution can be shown to be rejected statistically at a high significance level in favour of the NBD. Thereafter, we investigate whether these distributions fit the observed distributions of seismicity. For this purpose, we study upper statistical moments of earthquake numbers (skewness and kurtosis) and compare them to the theoretical values for both distributions. Empirical values for the skewness and the kurtosis increase for the smaller magnitude threshold and increase with even greater intensity for small temporal subdivision of catalogues. The Poisson distribution for large rate values approaches the Gaussian law, therefore its skewness

  15. Volume 9 Number 3

    African Journals Online (AJOL)

    OLUWOLE

    Volume 9 Number 3 September 2010 pp. 200 - 208. ISSN 1119-7455. EFFECTS OF PROCESSING METHODS ON THE CHEMICAL. COMPOSITION OF FLOUR, MOINMOIN AND AKARA FROM Mucuna pruriens. Asogwa, I.S 1and Onweluzo, J.C2. 1Dept. of Food Science and Technology, University of Mkar, Benue State, ...

  16. The Congruent Number Problem

    Indian Academy of Sciences (India)

    indebtedness to his remote predecessor. Since t/l.en the theory of elliptic curves, and its genemlizations to curves of higher genus and to abelian varieties, has bee?1 one of the main topics of modern number theory. Fermat's name, and his method of infinite desce1}-t, are indissolubly bound with it; they promise to remain so ...

  17. Factoring Fermat Numbers

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 1; Issue 1. Factoring Fermat Numbers. C E Veni Madhavan. Research News Volume 1 Issue 1 January 1996 pp 108-108. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/001/01/0108-0108. Author Affiliations.

  18. The Class Number Problem

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 3; Issue 6. The Class Number Problem - Binary Quadratic Forms. Rajat Tandon. General Article Volume 3 Issue ... Author Affiliations. Rajat Tandon1. Department of Mathematics, University of Hyderabad, Central University P.O. Hyderabad 500 046. India ...

  19. The Mystery of Numbers

    Indian Academy of Sciences (India)

    It was proved in the nineteenth century that the number of primes less than or equal to n approaches n/logn as n becomes very large. With modern computing and cryptography, the search for large primes has gained further impe- tus. Expected to find a prime with 10 million digits within a year... – p.22/22.

  20. Littlewood and Number Theory

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 18; Issue 9. Littlewood and Number Theory. M Ram Murty. General Article Volume 18 Issue 9 September 2013 pp 789-798. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/018/09/0789-0798. Keywords.

  1. Introducing Complex Numbers

    Science.gov (United States)

    Trudgian, Timothy

    2009-01-01

    One of the difficulties in any teaching of mathematics is to bridge the divide between the abstract and the intuitive. Throughout school one encounters increasingly abstract notions, which are more and more difficult to relate to everyday experiences. This article examines a familiar approach to thinking about negative numbers, that is an…

  2. The magic of numbers

    CERN Document Server

    Bell, Eric Temple

    1991-01-01

    From one of the foremost interpreters for lay readers of the history and meaning of mathematics: a stimulating account of the origins of mathematical thought and the development of numerical theory. It probes the work of Pythagoras, Galileo, Berkeley, Einstein, and others, exploring how ""number magic"" has influenced religion, philosophy, science, and mathematics

  3. Colour by Numbers

    Science.gov (United States)

    Wetherell, Chris

    2017-01-01

    This is an edited extract from the keynote address given by Dr. Chris Wetherell at the 26th Biennial Conference of the Australian Association of Mathematics Teachers Inc. The author investigates the surprisingly rich structure that exists within a simple arrangement of numbers: the times tables.

  4. Paint by Numbers Revived!

    Science.gov (United States)

    Hahn, Nic

    2012-01-01

    Remember paint by numbers? This revived trend was a perfect solution to teaching geometric shapes to the author's first-grade students. Geometric shapes are identified and used in early elementary art classrooms, but this lesson gives students a deeper understanding of shape, encourages problem-solving, and makes a strong correlation between math…

  5. Number Theory and Combinatorics

    Indian Academy of Sciences (India)

    2012-02-24

    Feb 24, 2012 ... able to a motivated undergraduate or postgraduate student. It may be somewhat of a challenge to make it ...... A quote attributed to the famous mathematician L Kronecker is 'Die. Ganzen Zahlen hat Gott gemacht, alles ...... Interestingly, Bertrand's motivation was to group theory and not really number theory ...

  6. Physical Constraints of Numbers

    OpenAIRE

    Mueckenheim, W.

    2005-01-01

    All sciences need and many arts apply mathematics whereas mathematics seems to be independent of all of them, but only based upon logic. This conservative concept, however, needs to be revised because, contrary to Platonic idealism (frequently called "realism" by mathematicians), mathematical ideas, notions, and, in particular, numbers are not at all independent of physical laws and prerequisites.

  7. Biting into Big Numbers.

    Science.gov (United States)

    Anderson, Maureen McCahan

    1996-01-01

    A mnemonic clue sentence--"He thinks mice bite trees"--is suggested for helping students with learning disabilities or mild mental retardation successfully identify up to 15 digit numbers by relating the sentence to the sequence of hundreds, thousands, millions, billions, and trillions. (DB)

  8. Fermion Number Fractionization

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 13; Issue 8. Fermion Number Fractionization. Kumar Rao Narendra Sahu Prasanta K ... Author Affiliations. Kumar Rao1 Narendra Sahu1 Prasanta K Panigrahi1. Theoretical Physics Division, Physical Research Laboratory, Ahmedabad 380 009, India ...

  9. Factoring Fermat Numbers

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 1; Issue 1. Factoring Fermat Numbers. C E Veni Madhavan. Research News Volume 1 Issue 1 January 1996 pp 108-108. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/001/01/0108-0108 ...

  10. ALARA notes, Number 8

    International Nuclear Information System (INIS)

    Khan, T.A.; Baum, J.W.; Beckman, M.C.

    1993-10-01

    This document contains information dealing with the lessons learned from the experience of nuclear plants. In this issue the authors tried to avoid the 'tyranny' of numbers and concentrated on the main lessons learned. Topics include: filtration devices for air pollution abatement, crack repair and inspection, and remote handling equipment

  11. Volume 9 Number 3

    African Journals Online (AJOL)

    OLUWOLE

    separately to eggs in the hatch; every treatment was replicated eight times. Observations on cumulative egg hatch were made every 24 hours for six consecutive days. This was done by counting the number of second stage juvenile which emerged from egg using stereomicroscope. Juvenile mortality observation: Ten ...

  12. The Brothel Phone Number

    DEFF Research Database (Denmark)

    Korsby, Trine Mygind

    2017-01-01

    in turn cultivate and maximize uncertainty about themselves in others. When making the move to go abroad into unknown terrains, accessing the infrastructure generated by the phone number can provide certainty and consolidate one’s position within criminal networks abroad. However, at the same time...

  13. Uniform random number generators

    Science.gov (United States)

    Farr, W. R.

    1971-01-01

    Methods are presented for the generation of random numbers with uniform and normal distributions. Subprogram listings of Fortran generators for the Univac 1108, SDS 930, and CDC 3200 digital computers are also included. The generators are of the mixed multiplicative type, and the mathematical method employed is that of Marsaglia and Bray.

  14. Typical Complexity Numbers

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. Typical Complexity Numbers. Say. 1000 tones,; 100 Users,; Transmission every 10 msec. Full Crosstalk cancellation would require. Full cancellation requires a matrix multiplication of order 100*100 for all the tones. 1000*100*100*100 operations every second for the ...

  15. Predicting Lotto Numbers

    NARCIS (Netherlands)

    Jorgensen, C.B.; Suetens, S.; Tyran, J.R.

    2011-01-01

    We investigate the "law of small numbers" using a unique panel data set on lotto gambling. Because we can track individual players over time, we can measure how they react to outcomes of recent lotto drawings. We can therefore test whether they behave as if they believe they can predict lotto

  16. Number Theory and Combinatorics

    Indian Academy of Sciences (India)

    cles on Number Theory and Combinatorics comprise the present book. He ..... Galois theory. In the case of the circle, the Galois group of the cyclotomic extension is the multiplicative group of integers modulo n which are coprime to n. This latter group is ...... Pillai proves that when t = n and the game is carefully played, then it.

  17. Theoretical model of laminar flow in a channel or tube under ocean conditions

    International Nuclear Information System (INIS)

    Yan, B.H.; Yu, L.; Yang, Y.H.

    2011-01-01

    Research highlights: → The theoretical model of laminar flow in channels under ocean conditions is established. → The frictional resistance coefficient and Nusselt number are also obtained. → The theoretical results are in agreement with experimental data. → The oscillation of parameters is induced by the tangential force. -- Abstract: The theoretical model of laminar flow in a channel or tube under ocean conditions is established. The velocity and temperature correlations are derived, and the frictional resistance coefficient and Nusselt number are also obtained. The theoretical results are in agreement with experimental data. The oscillation of parameters is induced by the tangential force due to ocean conditions. The effect of centrifugal and Coriolis forces on the flow is negligible. The effects of several parameters on the frictional resistance coefficient and Nusselt number are investigated. The oscillating amplitude of Nusselt number increases with the increasing of Prandtl number. Both the oscillating amplitudes of frictional resistance coefficient and Nusselt number increase with the increasing of rolling frequency.

  18. Association of adiponectin, interleukin (IL)-1ra, inducible protein 10, IL-6 and number of islet autoantibodies with progression patterns of type 1 diabetes the first year after diagnosis

    DEFF Research Database (Denmark)

    Kaas, A; Pfleger, Claudia Christina; Hansen, Lene

    2010-01-01

    The progression of type 1 diabetes after diagnosis is poorly understood. Our aim was to assess the relation of disease progression of juvenile-onset type 1 diabetes, determined by preserved beta cell function the first year after diagnosis, with systemic cytokine concentrations and number...

  19. THE EFFECT OF BETA GLUCAN OF SACCHAROMYCES CEREVISAE ON THE INCREASE OF THE NUMBER OF BRAIN CELLS IN SUBSTANTIA NIGRA BRAIN OF PARKINSON’S WISTAR STRAIN RAT (RATTUS NORVEGICUS MODEL INDUCED WITH ROTENONE

    Directory of Open Access Journals (Sweden)

    Masruroh Rahayu

    2015-01-01

    Full Text Available ackground and aims. One of many neurodegenerative diseases afflicting the elderly is Parkinson. Beta glucan from Saccharomyces cerevisae is very potential to be used as a regenerative therapy of Parkinson's disease. Beta glucan can increase the mobilization of hematopoietic stem cells (HSCs from the bone marrow into the damaged tissues. Hematopoietic stem cells (HSCs which have been mobilized can regenerate and differentiate into brain cells so that the symptoms of Parkinson would be reduced. This research aims to find out the effects of the addition of Saccharomyces cerevisae toward the number of brain cells in substantia nigra Parkinson’s rat model. Method. The research was experimental in vivo using the draft of randomized post test only controlled group design. There were five groups that become the sample in this research with 5 rats for each group, i.e. negative control group, positive control group, Treatment Group 1, 2 and 3 (Rotenone + Saccharomyces cerevisae 18 mg/kgBB, 36 mg/kgBB, 72 mg/kgBBfor 4 weeks. Variable measured in this study was the number of brain cells in substantia nigra. The results of this study showed that Treatment Group 3 (72 mg/kgBB was a group with the largest number of brain cells than the other treatment groups. Statistical data obtained showed that the average number of brain cells in negative control group was 192.00 cells; positive control amounted to 116.80 cells; Treatment 1 amounted to 135.40 cells; Treatment 2 amounted to 140.80 cells; and Treatment 3 amounted to 161.80 cells. Result. The result of ANOVA test showed a significant difference between groups (p< 0.05, while the correlation test result indicated a strong correlation between the dose of Saccharomyces cerevisae and the number of substantia nigra of rat’s brain cells (r = 0,818. Conclusion. From this research, it can be concluded that the addition of Saccharomyces cerevisae with a dose of 18mg/kgBB, 36mg/kgBBdan 72 mg/kgBB is able to increase

  20. Optokinetic Stimulation Modulates Neglect for the Number Space: Evidence from Mental Number Interval Bisection

    Science.gov (United States)

    Priftis, Konstantinos; Pitteri, Marco; Meneghello, Francesca; Umiltà, Carlo; Zorzi, Marco

    2012-01-01

    Behavioral, neuropsychological, and neuroimaging data support the idea that numbers are represented along a mental number line (MNL), an analogical, visuospatial representation of number magnitude. The MNL is left-to-right oriented in Western cultures, with small numbers on the left and larger numbers on the right. Left neglect patients are impaired in the mental bisection of numerical intervals, with a bias toward larger numbers that are relatively to the right on the MNL. In the present study we investigated the effects of optokinetic stimulation (OKS) – a technique inducing visuospatial attention shifts by means of activation of the optokinetic nystagmus – on number interval bisection. One patient with left neglect following right-hemisphere stroke (BG) and four control patients with right-hemisphere damage, but without neglect, performed the number interval bisection task in three conditions of OKS: static, leftward, and rightward. In the static condition, BG misbisected to the right of the true midpoint. BG misbisected to the left following leftward OKS, and again to the right of the midpoint following rightward OKS. Moreover, the variability of BG’s performance was smaller following both leftward and rightward OKS, suggesting that the attentional bias induced by OKS reduced the “indifference zone” that is thought to underlie the length effect reported in bisection tasks. We argue that shifts of visuospatial attention, induced by OKS, may affect number interval bisection, thereby revealing an interaction between the processing of the perceptual space and the processing of the number space. PMID:22363280

  1. Numbers and sets

    Directory of Open Access Journals (Sweden)

    Marco Ruffino

    2001-12-01

    Full Text Available In this paper I discuss the intuition behind Frege's and Russell's definitions of numbers as sets, as well as Benacerraf's criticism of it. I argue that Benacerraf's argument is not as strong as some philosophers tend to think. Moreover, I examine an alternative to the Fregean-Russellian definition of numbers proposed by Maddy, and point out some problems faced by it.Neste artigo discuto a intuição subjacente à definição de n∨meros como conjuntos proposta por Frege e Russell, assim como a crítica de Benacerraf a esta definição. Eu tento mostrar que o argumento de Benacerraf não é tão forte como alguns filósofos o tomaram. Adicionalmente, examino uma alternativa à definição de Frege e Russell proposta por Maddy, e indico algumas dificuldades encontrada pela mesma.

  2. Chromosome numbers in Bromeliaceae

    OpenAIRE

    Cotias-de-Oliveira,Ana Lúcia Pires; Assis,José Geraldo Aquino de; Bellintani,Moema Cortizo; Andrade,Jorge Clarêncio Souza; Guedes,Maria Lenise Silva

    2000-01-01

    The present study reports chromosome numbers of 17 species of Bromeliaceae, belonging to the genera Encholirium, Bromelia, Orthophytum, Hohenbergia, Billbergia, Neoglaziovia, Aechmea, Cryptanthus and Ananas. Most species present 2n = 50, however, Bromelia laciniosa, Orthophytum burle-marxii and O. maracasense are polyploids with 2n = 150, 2n = 100 and 2n = 150, respectively, while for Cryptanthus bahianus, 2n = 34 + 1-4B. B chromosomes were observed in Bromelia plumieri and Hohenbergia aff. u...

  3. Number Needed To… $ave?

    Science.gov (United States)

    Rocker, Graeme M; Verma, Jennifer Y; Demmons, Jillian; Mittmann, Nicole

    2015-02-06

    The 'Number Needed to Treat' (NNT) is a useful measure for estimating the number of patients that would need to receive a therapeutic intervention to avoid one of the adverse events that the treatment is designed to prevent. We explored the possibility of an adaption of NNT to estimate the 'Number Needed to $ave' (NN$) as a new, conceptual systems metric to estimate potential cost-savings to the health system from implementation of a treatment, or in this case, a program. We used the outcomes of the INSPIRED COPD Outreach ProgramTM to calculate that 26 patients would need to complete the program to avoid healthcare expenditures of $100,000, based on hospital bed days avoided. The NN$ does not translate into 'cost savings' per se, but redirection of resource expenditures for other purposes. We propose that the NN$ metric, if further developed, could help to inform system-level resource allocation decisions in a manner similar to the way that the NNT metric helps to inform individual-level treatment decisions.

  4. Association of adiponectin, interleukin (IL)-1ra, inducible protein 10, IL-6 and number of islet autoantibodies with progression patterns of type 1 diabetes the first year after diagnosis

    DEFF Research Database (Denmark)

    Kaas, A; Pfleger, Claudia Christina; Hansen, Lene

    2010-01-01

    of autoantibodies. Juvenile patients (n = 227) had a meal-stimulated C-peptide test 1 and 6 months after diagnosis. On the basis of the C-peptide course for the duration of 1-6 months, four progression groups were defined: patients with persistently low beta cell function ('stable-low'), rapid progressers, slow...... progressers and remitters. Serum concentrations of adiponectin, interleukin (IL)-1ra, inducible protein 10 (IP-10), IL-6 and glutamic acid decarboxylase (GAD), IA-2A and islet-cell antibodies (ICA) were measured at 1, 6 and 12 months. We found that adiponectin concentrations at 1 month predicted disease...

  5. The number system

    CERN Document Server

    Thurston, H A

    2007-01-01

    The teaching of mathematics has undergone extensive changes in approach, with a shift in emphasis from rote memorization to acquiring an understanding of the logical foundations and methodology of problem solving. This book offers guidance in that direction, exploring arithmetic's underlying concepts and their logical development.This volume's great merit lies in its wealth of explanatory material, designed to promote an informal and intuitive understanding of the rigorous logical approach to the number system. The first part explains and comments on axioms and definitions, making their subseq

  6. On Dimensionless Numbers

    Czech Academy of Sciences Publication Activity Database

    Růžička, Marek

    2008-01-01

    Roč. 86, č. 8A (2008), s. 835-868 ISSN 0263-8762 R&D Projects: GA ČR GA104/06/1418; GA ČR GA104/07/1110; GA AV ČR IAAX00130702; GA AV ČR(CZ) IAA200720801; GA MŠk ME 952 Institutional research plan: CEZ:AV0Z40720504 Keywords : dimensionless numbers * dimensional analysis * scaling of equation s Subject RIV: CI - Industrial Chemistry, Chemical Engineering Impact factor: 0.989, year: 2008

  7. Topics in number theory

    CERN Document Server

    LeVeque, William J

    2002-01-01

    Classic two-part work now available in a single volume assumes no prior theoretical knowledge on reader's part and develops the subject fully. Volume I is a suitable first course text for advanced undergraduate and beginning graduate students. Volume II requires a much higher level of mathematical maturity, including a working knowledge of the theory of analytic functions. Contents range from chapters on binary quadratic forms to the Thue-Siegel-Roth Theorem and the Prime Number Theorem. Includes numerous problems and hints for their solutions. 1956 edition. Supplementary Reading. List of Symb

  8. Fractional fermion number and its thermal effect

    International Nuclear Information System (INIS)

    Midorikawa, Shoichi.

    1984-06-01

    We give the general method to calculate fermion numbers induced on solitons in quantum field theory. Our method preserves the symmetry of the Lagrangian. We also extend our analysis to the case of finite temperatures, where we compare our analysis with others. (author)

  9. Association of adiponectin, interleukin (IL)-1ra, inducible protein 10, IL-6 and number of islet autoantibodies with progression patterns of type 1 diabetes the first year after diagnosis

    DEFF Research Database (Denmark)

    Kaas, A; Pfleger, Claudia Christina; Hansen, Lene

    2010-01-01

    progressers and remitters. Serum concentrations of adiponectin, interleukin (IL)-1ra, inducible protein 10 (IP-10), IL-6 and glutamic acid decarboxylase (GAD), IA-2A and islet-cell antibodies (ICA) were measured at 1, 6 and 12 months. We found that adiponectin concentrations at 1 month predicted disease...... progression at 6 months (P = 0·04). Patients with low adiponectin had a higher probability of becoming remitters than rapid progressers, odds ratio 3·1 (1·3-7·6). At 6 and 12 months, adiponectin differed significantly between the groups, with highest concentrations among stable-low and rapid progressers...... concentration at 1 month predicts, and at 6 and 12 months associates with, distinct progression patterns....

  10. Number Theoretic Background

    Science.gov (United States)

    Rudnick, Z.

    Contents: 1. Introduction 2. Divisibility 2.1. Basics on Divisibility 2.2. The Greatest Common Divisor 2.3. The Euclidean Algorithm 2.4. The Diophantine Equation ax+by=c 3. Prime Numbers 3.1. The Fundamental Theorem of Arithmetic 3.2. There Are Infinitely Many Primes 3.3. The Density of Primes 3.4. Primes in Arithmetic Progressions 4. Continued Fractions 5. Modular Arithmetic 5.1. Congruences 5.2. Modular Inverses 5.3. The Chinese Remainder Theorem 5.4. The Structure of the Multiplicative Group (Z/NZ)^* 5.5. Primitive Roots 6. Quadratic Congruences 6.1. Euler's Criterion 6.2. The Legendre Symbol and Quadratic Reciprocity 7. Pell's Equation 7.1. The Group Law 7.2. Integer Solutions 7.3. Finding the Fundamental Solution 8. The Riemann Zeta Function 8.1 Analytic Continuation and Functinal Equation of ζ(s) 8.2 Connecting the Primes and the Zeros of ζ(s) 8.3 The Riemann Hypothesis References

  11. [The power of numbers].

    Science.gov (United States)

    van Gijn, J

    2000-01-01

    The round figure for the current year has stirred people's minds in anticipation. Numbers have acquired great significance also in today's medical science. The Paris physician Pierre Charles Alexandre Louis (1787-1872) is considered the founding father of the numerical method in medicine. At first the principle of aggregating data from different individuals aroused much resistance and even disgust: Claude Bernard was a leading figure among those who warned that one will never find a mean in nature, and that grouping findings together obscures the true relationship between biological phenomena. True enough, statistical significance is not a characteristic of nature itself. Significant differences or risk reductions do not necessarily imply clinical relevance, and results obtained in a group of patients are rarely applicable to an individual patient in the consultation room. Likewise, the health of a human being cannot be captured in biochemical, radiological or other technical measures, nor in disease-specific scales that reduce well-being to one or two digits. The editors of this journal will remain keen on publishing numerical studies that contribute to evidence-based medicine, but at the same time they will continue to foster the art of reporting illness from the point of view of the sick person.

  12. Optokinetic stimulation modulates neglect for the number space: Evidence from mental number interval bisection

    Directory of Open Access Journals (Sweden)

    Konstantinos ePriftis

    2012-02-01

    Full Text Available Behavioral, neuropsychological, and neuroimaging data support the idea that numbers are represented along a mental number line (MNL, an analogical, visuo-spatial representation of number magnitude. The MNL is left-to-right oriented, with small numbers on the left and larger numbers on the right. Left neglect patients are impaired in processing the left side of the MNL and show a rightward deviation in the mental bisection of numerical intervals. In the present study we investigated the effects of optokinetic stimulation (OKS -a technique inducing spatial attention shifts by means of activation of the optokinetic nystagmus- on mental number interval bisection. One patient with left neglect following right hemisphere stroke (BG and four control patients with right hemisphere damage, but without neglect, performed the mental number interval bisection task in three experimental conditions of OKS: static, leftward, and rightward. In the static condition, BG misbisected to the right of the true midpoint. BG misbisected to the left following leftward OKS, but again to the right of the midpoint following rightward OKS. In contrast, the performance of controls was not significantly affected by the direction of OKS. We argue that shifts of visuospatial attention, induced by OKS, may affect the mental number interval bisection, suggesting the presence of an interaction between the processing of number magnitude and the processing of the perceptual space, in patients with neglect for the mental number space.

  13. Influence of the number and interval of treatment cycles on cytokine-induced killer cells and their adjuvant therapeutic effects in advanced non-small-cell lung cancer (NSCLC).

    Science.gov (United States)

    Gu, Yuanlong; Lv, Huimin; Zhao, Juan; Li, Qi; Mu, Guannan; Li, Jiade; Wuyang, Jiazi; Lou, Ge; Wang, Ruitao; Zhang, Yanqiao; Huang, Xiaoyi

    2017-09-01

    Cytokine-induced killer (CIK) cells have important therapeutic effects in adoptive cell transfer (ACT) for the treatment of various malignancies. In this study, we focused on in vitro expansion of CIK cells and their clinical efficacy in combination with chemotherapy in patients with advanced non-small-cell lung cancer (NSCLC). A total of 64 patients with NSCLC (enrolled from 2011 to 2012), including 32 patients who received chemotherapy alone or with sequential radiotherapy (conventional treatment, control group) and 32 patients who received conventional treatment and sequential CIK infusion (study group), were retrospectively analyzed. The time to progression (TTP), overall survival (OS) and adverse effects were analyzed and the phenotype of lymphocytes in CIK population was also determined by flow cytometry. After in vitro expansion, the average percentage of CIK cells was 26.35%. During the 54-month follow up, the median OS and TTP were significantly longer in the study group than in the control group (P=0.0189 and P=0.0129, respectively). The median OS of the ACT≥4cycles subgroup was significantly longer than that of the ACTcells in patients who received ≥4cycles of ACT was higher than that in patients treated with cells were difficult to expand in vitro in some patients after the first ACT cycle but became much easier as the treatment cycles increased monthly. Longer treatment interval negatively impacted the expansion of CIK cells. Systematic immune levels can be increasingly boosted by reinfusion of ACT. Conventional treatment plus CIK cells is an effective therapeutic strategy to prevent progression and prolong survival of patients with advanced NSCLC. Copyright © 2017. Published by Elsevier B.V.

  14. Natural convection inside an irregular porous cavity

    International Nuclear Information System (INIS)

    Beltran, Jorge I. LLagostera; Trevisan, Osvair Vidal

    1990-01-01

    Natural convection flow induced by heating from below in a irregular porous cavity is investigated numerically. The influence of the modified Rayleigh number and geometric ratios on heat transfer and fluid flow is studied. Global and local Nusselt for Rayleigh numbers covering the range 0 - 1600 and for several geometric ratios. The fluid flow and the temperature field are illustrated by contour maps. (author)

  15. Depletion of Regulatory T Cells Induces High Numbers of Dendritic Cells and Unmasks a Subset of Anti-Tumour CD8+CD11c+ PD-1lo Effector T Cells.

    Directory of Open Access Journals (Sweden)

    Nicolas Goudin

    Full Text Available Natural regulatory T (Treg cells interfere with multiple functions, which are crucial for the development of strong anti-tumour responses. In a model of 4T1 mammary carcinoma, depletion of CD25+Tregs results in tumour regression in Balb/c mice, but the mechanisms underlying this process are not fully understood. Here, we show that partial Treg depletion leads to the generation of a particular effector CD8 T cell subset expressing CD11c and low level of PD-1 in tumour draining lymph nodes. These cells have the capacity to migrate into the tumour, to kill DCs, and to locally regulate the anti-tumour response. These events are concordant with a substantial increase in CD11b+ resident dendritic cells (DCs subsets in draining lymph nodes followed by CD8+ DCs. These results indicate that Treg depletion leads to tumour regression by unmasking an increase of DC subsets as a part of a program that optimizes the microenvironment by orchestrating the activation, amplification, and migration of high numbers of fully differentiated CD8+CD11c+PD1lo effector T cells to the tumour sites. They also indicate that a critical pattern of DC subsets correlates with the evolution of the anti-tumour response and provide a template for Treg depletion and DC-based therapy.

  16. mTOR Hyperactivation by Ablation of Tuberous Sclerosis Complex 2 in the Mouse Heart Induces Cardiac Dysfunction with the Increased Number of Small Mitochondria Mediated through the Down-Regulation of Autophagy.

    Directory of Open Access Journals (Sweden)

    Manabu Taneike

    Full Text Available Mammalian target of rapamycin complex 1 (mTORC1 is a key regulator of cell growth, proliferation and metabolism. mTORC1 regulates protein synthesis positively and autophagy negatively. Autophagy is a major system to manage bulk degradation and recycling of cytoplasmic components and organelles. Tuberous sclerosis complex (TSC 1 and 2 form a heterodimeric complex and inactivate Ras homolog enriched in brain, resulting in inhibition of mTORC1. Here, we investigated the effects of hyperactivation of mTORC1 on cardiac function and structure using cardiac-specific TSC2-deficient (TSC2-/- mice. TSC2-/- mice were born normally at the expected Mendelian ratio. However, the median life span of TSC2-/- mice was approximately 10 months and significantly shorter than that of control mice. TSC2-/- mice showed cardiac dysfunction and cardiomyocyte hypertrophy without considerable fibrosis, cell infiltration or apoptotic cardiomyocyte death. Ultrastructural analysis of TSC2-/- hearts revealed misalignment, aggregation and a decrease in the size and an increase in the number of mitochondria, but the mitochondrial function was maintained. Autophagic flux was inhibited, while the phosphorylation level of S6 or eukaryotic initiation factor 4E -binding protein 1, downstream of mTORC1, was increased. The upregulation of autophagic flux by trehalose treatment attenuated the cardiac phenotypes such as cardiac dysfunction and structural abnormalities of mitochondria in TSC2-/- hearts. The results suggest that autophagy via the TSC2-mTORC1 signaling pathway plays an important role in maintenance of cardiac function and mitochondrial quantity and size in the heart and could be a therapeutic target to maintain mitochondrial homeostasis in failing hearts.

  17. [Intel random number generator-based true random number generator].

    Science.gov (United States)

    Huang, Feng; Shen, Hong

    2004-09-01

    To establish a true random number generator on the basis of certain Intel chips. The random numbers were acquired by programming using Microsoft Visual C++ 6.0 via register reading from the random number generator (RNG) unit of an Intel 815 chipset-based computer with Intel Security Driver (ISD). We tested the generator with 500 random numbers in NIST FIPS 140-1 and X(2) R-Squared test, and the result showed that the random number it generated satisfied the demand of independence and uniform distribution. We also compared the random numbers generated by Intel RNG-based true random number generator and those from the random number table statistically, by using the same amount of 7500 random numbers in the same value domain, which showed that the SD, SE and CV of Intel RNG-based random number generator were less than those of the random number table. The result of u test of two CVs revealed no significant difference between the two methods. Intel RNG-based random number generator can produce high-quality random numbers with good independence and uniform distribution, and solves some problems with random number table in acquisition of the random numbers.

  18. Cordial Languages and Cordial Numbers

    Directory of Open Access Journals (Sweden)

    J. Baskar BABUJEE

    2012-01-01

    Full Text Available The concept of cordial labeling in graphs motivated us to introduce cordial words, cordial languages and cordial numbers. We interpret the notion of cordial labeling in Automata and thereby study the corresponding languages. In this paper we develop a new sequence of numbers called the cordial numbers in number theory using the labeling techniques in graph theory on automata theory.

  19. Bell numbers, determinants and series

    Indian Academy of Sciences (India)

    In this article, we study Bell numbers and Uppuluri Carpenter numbers. We obtain various expressions and relations between them. These include polynomial recurrences and expressions as determinants of certain matrices of binomial coefficients. Keywords. p-adic series; Bell numbers. 1. Introduction. Bell numbers, Bn [2] ...

  20. Cosmic numbers the numbers that define our universe

    CERN Document Server

    Stein, James D

    2011-01-01

    Our fascination with numbers begins when we are children and continues throughout our lives. We start counting our fingers and toes and end up balancing checkbooks and calculating risk. So powerful is the appeal of numbers that many people ascribe to them a mystical significance. Other numbers go beyond the supernatural, working to explain our universe and how it behaves. In Cosmic Numbers , mathematics professor James D. Stein traces the discovery, evolution, and interrelationships of the numbers that define our world. Everyone knows about the speed of light and absolute zero, but numbers lik

  1. Fermion number in supersymmetric models

    International Nuclear Information System (INIS)

    Mainland, G.B.; Tanaka, K.

    1975-01-01

    The two known methods for introducing a conserved fermion number into supersymmetric models are discussed. While the introduction of a conserved fermion number often requires that the Lagrangian be massless or that bosons carry fermion number, a model is discussed in which masses can be introduced via spontaneous symmetry breaking and fermion number is conserved at all stages without assigning fermion number to bosons. (U.S.)

  2. THE RELATIONSHIP BETWEEN NUMBER NAMES AND NUMBER CONCEPTS

    DEFF Research Database (Denmark)

    Ejersbo, Lisser Rye; Misfeldt, Morten

    Different countries have different names for numbers. These names are often related in a regular way to the base-10 place value system used for writing numbers as digits. However, in several languages, this regularity breaks down (e.g., between 10 and 20), and there is limited knowledge of how...... the regularity or irregularity of number naming affects children’s formation of number concepts and arithmetic performance. We investigate this issue by reviewing relevant literature and undertaking a design research project addressing the specific irregularities of the Danish number names. In this project......, a second, regular set of number names is introduced in primary school. The study’s findings suggest that the regularity of number names influences the development of number concepts and creates a positive impact on the understanding of the base-10 system....

  3. Comparative study on the influence of depth, number and arrangement of dimples on the flow and heat transfer characteristics at turbulent flow regimes

    Science.gov (United States)

    Nazari, Saeed; Zamani, Mahdi; Moshizi, Sajad A.

    2018-03-01

    The ensuing study is dedicated to a series of numerical investigations concerning the effects of various geometric parameters of dimpled plates on the flow structure and heat transfer performance in a rectangular duct compared to the smooth plate. These parameters are the arrangement, number and depth of dimples. Two widely used staggered and square patterns in addition to a triangular arrangement, and three dimple depths (Δ = δ/d = 0.25, 0.375 and 0.5) have been chosen for this particular study. All studies have been conducted at three different Reynolds numbers Re = 25,000, 50,000 and 100,000. In order to capture the flow structures in the vicinity of dimples and contributing phenomena related to the boundary layer interactions, fully structured grids with y+ rims of dimples are the causes for improved average Nusselt number in the dimpled surface in comparison to the smooth plate. However, more pressure loss due to the higher friction drag and recirculation zones inside dimples will exist as a drawback in this system. Moreover, for all arrangements increasing dimple ratio Δ has a negative impact on the heat transfer augmentation and also deteriorates the pressure loss, which leads to this fact that Δ = 0.25 serves as the best option for the dimple depth.

  4. Heat or mass transfer at low Péclet number for Brinkman and Darcy flow round a sphere

    KAUST Repository

    Bell, Christopher G.

    2014-01-01

    Prior research into the effect of convection on steady-state mass transfer from a spherical particle embedded in a porous medium has used the Darcy model to describe the flow. However, a limitation of the Darcy model is that it does not account for viscous effects near boundaries. Brinkman modified the Darcy model to include these effects by introducing an extra viscous term. Here we investigate the impact of this extra viscous term on the steady-state mass transfer from a sphere at low Péclet number, Pe 1. We use singular perturbation techniques to find the approximate asymptotic solution for the concentration profile. Mass-release from the surface of the sphere is described by a Robin boundary condition, which represents a first-order chemical reaction. We find that a larger Brinkman viscous boundary layer renders mass transport by convection less effective, and reduces the asymmetry in the peri-sphere concentration profiles. We provide simple analytical expressions that can be used to calculate the concentration profiles, as well as the local and average Sherwood numbers; and comparison to numerical simulations verifies the order of magnitude of the error in the asymptotic expansions. In the appropriate limits, the asymptotic results agree with solutions previously obtained for Stokes and Darcy flow. The solution for Darcy flow with a Robin boundary condition has not been considered previously in the literature and is a new result. Whilst the article has been formulated in terms of mass transfer, the analysis is also applicable to heat transfer, with concentration replaced by temperature and the Sherwood number by the Nusselt number. © 2013 Elsevier Ltd. All rights reserved.

  5. How Spencer Made Number: First Uses of the Number Words

    Science.gov (United States)

    Mix, Kelly S.

    2009-01-01

    This article describes the development of number concepts between infancy and early childhood. It is based on a diary study that tracked number word use in a child from 12 to 38 months of age. Number words appeared early in the child's vocabulary, but accurate reference to specific numerosities evolved gradually over the entire 27-month period.…

  6. A minimum number of autoimmune T cells to induce autoimmunity?

    Czech Academy of Sciences Publication Activity Database

    Bosch, A.J.T.; Bolinger, B.; Keck, S.; Štěpánek, Ondřej; Ozga, A.J.; Galati-Fournier, V.; Stein, J.V.; Palmer, E.

    2017-01-01

    Roč. 316, jaro (2017), s. 21-31 ISSN 0008-8749 R&D Projects: GA ČR GJ16-09208Y Institutional support: RVO:68378050 Keywords : T cell * Tolerance * Autoimmunity Subject RIV: EB - Genetics ; Molecular Biology OBOR OECD: Immunology Impact factor: 3.172, year: 2016

  7. Beyond the Numbers: Understanding the Transformation Induced by INDCs

    International Nuclear Information System (INIS)

    Spencer, Thomas; Pierfederici, Roberta; Waisman, Henri; Colombier, Michel; Bertram, Christoph; Kriegler, Elmar; Luderer, Gunnar; Humpenoeder, Florian; Popp, Alexander; Edenhofer, Ottmar; Den Elzen, Michel; Van Vuuren, Detlef; Van Soest, Heleen; Paroussos, Leonidas; Fragkos, Panagiotis; Kainuma, Mikiko; Masui, Toshihiko; Oshiro, Ken; Akimoto, Keigo; Shoai Tehrani, Bianka; Sano, Fuminori; Oda, Junichiro; Clarke, Leon; Iyer, Gokul; Edmonds, Jae; TENG, Fei; FU, Sha; Kejun, Jiang; Koeberle, Alexandre C.; Szklo, Alexandre; Lucena, Andre F.P.; Portugal-Pereira, Joana; Rochedo, Pedro; Schaeffer, Roberto; Awasthy, Aayushi; Kumar Shrivastava, Manish; Mathur, Ritu; Rogelj, Joeri; Jewell, Jessica; Riahi, Keywan; Garg, Amit

    2015-10-01

    The present analysis of the contributions (INDCs) submitted by Member States to the United Nations Framework Convention on Climate Change (UNFCCC) in the run-up to COP21 was conducted by leading research teams from Brazil, China, Japan, India, the United States and the European Union within the MILES Project (funded by the European Commission). By investigating the concrete implications of INDCs for the low-carbon transformation by and beyond 2030, from energy systems, buildings to transport and industry, this study complements the upcoming cutting-edge assessments by UNFCCC and UNEP of the impact of INDCs on global emissions and the global temperature goal. The 'Modelling and Informing Low-Emission Strategies' (MILES) project is an international research project bringing together 16 leading research teams in order to build capacity and knowledge on low-emissions development strategies. The objective of this report is to understand the implications of INDCs of the 5 countries and 1 region covered by the project (US, China, Japan, EU, Brazil and India), both at a national and global level, by investigating the concrete implications of INDCs for the low-carbon transformation by and beyond 2030, from energy systems, buildings to transport and industry. A significant transition appears in the electricity sector, where INDCs will further drive the transition towards renewables and other low-emissions forms of electricity production. In the six major economies assessed individually, carbon dioxide emissions per unit of electricity production falls by about 40% between 2010 and 2030 and renewable electricity becomes the dominant source of electricity production at about 36% of the electricity mix. Some crucial low-carbon solutions, like CCS, electric vehicles, advanced biofuels, sustainable urban planning, appear unlikely to be developed under the INDCs at the scale and speed required for a 2 deg. C scenario. Likewise, the report highlights that INDCs would leave too much inefficient and unabated fossil fuel capacity online in 2030 to be coherent with a 2 degrees scenario. This highlights the risks of lock-in into a high carbon trajectory if action is not strengthened quickly. Post-Paris policy efforts need to stimulate technology innovation, deployment and diffusion in order to drive down costs in such sectors where insufficient progress is being seen. The INDCs imply a significant acceleration of climate action but as currently submitted may not be enough to keep the below 2 deg. C goal in reach. The Paris Agreement should establish a clear mechanism to allow the regular, predictable and timely revision of national contributions and the global framework. New contributions should be based on a vision for the deep decarbonization of national energy systems. The Paris agreement should foster the development of national deep decarbonization pathways around 2018

  8. Number games, magnitude representation, and basic number skills in preschoolers.

    Science.gov (United States)

    Whyte, Jemma Catherine; Bull, Rebecca

    2008-03-01

    The effect of 3 intervention board games (linear number, linear color, and nonlinear number) on young children's (mean age = 3.8 years) counting abilities, number naming, magnitude comprehension, accuracy in number-to-position estimation tasks, and best-fit numerical magnitude representations was examined. Pre- and posttest performance was compared following four 25-min intervention sessions. The linear number board game significantly improved children's performance in all posttest measures and facilitated a shift from a logarithmic to a linear representation of numerical magnitude, emphasizing the importance of spatial cues in estimation. Exposure to the number card games involving nonsymbolic magnitude judgments and association of symbolic and nonsymbolic quantities, but without any linear spatial cues, improved some aspects of children's basic number skills but not numerical estimation precision.

  9. Elliptic Curves and Number Theory

    Indian Academy of Sciences (India)

    R. Sujatha, School of Mathematics, Tata Institute of Fundamental Research, Mumbai, INDIA

    1. Aim: To explain the connection between a simple ancient problem in number theory and a deep sophisticated conjecture about Elliptic Curves. ('arithmetic Geometry'). Notation: N : set of natural numbers (1,2,3,...) ...

  10. Bell numbers, determinants and series

    Indian Academy of Sciences (India)

    In this article, we study Bell numbers and Uppuluri Carpenter numbers. We obtain various expressions and relations between them. These include polynomial recurrences and expressions as determinants of certain matrices of binomial coefficients.

  11. Elementary number theory with programming

    CERN Document Server

    Lewinter, Marty

    2015-01-01

    A successful presentation of the fundamental concepts of number theory and computer programming Bridging an existing gap between mathematics and programming, Elementary Number Theory with Programming provides a unique introduction to elementary number theory with fundamental coverage of computer programming. Written by highly-qualified experts in the fields of computer science and mathematics, the book features accessible coverage for readers with various levels of experience and explores number theory in the context of programming without relying on advanced prerequisite knowledge and con

  12. Distribution theory of algebraic numbers

    CERN Document Server

    Yang, Chung-Chun

    2008-01-01

    The book timely surveys new research results and related developments in Diophantine approximation, a division of number theory which deals with the approximation of real numbers by rational numbers. The book is appended with a list of challenging open problems and a comprehensive list of references. From the contents: Field extensions Algebraic numbers Algebraic geometry Height functions The abc-conjecture Roth''s theorem Subspace theorems Vojta''s conjectures L-functions.

  13. Random Numbers and Quantum Computers

    Science.gov (United States)

    McCartney, Mark; Glass, David

    2002-01-01

    The topic of random numbers is investigated in such a way as to illustrate links between mathematics, physics and computer science. First, the generation of random numbers by a classical computer using the linear congruential generator and logistic map is considered. It is noted that these procedures yield only pseudo-random numbers since…

  14. Reynolds Stress Turbulence Model

    Directory of Open Access Journals (Sweden)

    Shuichi Torii

    1995-01-01

    the Reynolds stress in the inner wall region is substantially diminished due to the inner core movement, resulting in a decrease in the heat transfer performance, and (iii an increase in the velocity ratio of the moving inner core of the fluid flow induces a decrease in the Nusselt number as well as the Reynolds stress in the region near the inner core.

  15. 2016 Gainesville Number Theory Conference

    CERN Document Server

    Garvan, Frank

    2017-01-01

    Gathered from the 2016 Gainesville Number Theory Conference honoring Krishna Alladi on his 60th birthday, these proceedings present recent research in number theory. Extensive and detailed, this volume features 40 articles by leading researchers on topics in analytic number theory, probabilistic number theory, irrationality and transcendence, Diophantine analysis, partitions, basic hypergeometric series, and modular forms. Readers will also find detailed discussions of several aspects of the path-breaking work of Srinivasa Ramanujan and its influence on current research. Many of the papers were motivated by Alladi's own research on partitions and q-series as well as his earlier work in number theory.  Alladi is well known for his contributions in number theory and mathematics. His research interests include combinatorics, discrete mathematics, sieve methods, probabilistic and analytic number theory, Diophantine approximations, partitions and q-series identities. Graduate students and researchers will find th...

  16. Children's mappings between number words and the approximate number system.

    Science.gov (United States)

    Odic, Darko; Le Corre, Mathieu; Halberda, Justin

    2015-05-01

    Humans can represent number either exactly--using their knowledge of exact numbers as supported by language, or approximately--using their approximate number system (ANS). Adults can map between these two systems--they can both translate from an approximate sense of the number of items in a brief visual display to a discrete number word estimate (i.e., ANS-to-Word), and can generate an approximation, for example by rapidly tapping, when provided with an exact verbal number (i.e., Word-to-ANS). Here we ask how these mappings are initially formed and whether one mapping direction may become functional before the other during development. In two experiments, we gave 2-5 year old children both an ANS-to-Word task, where they had to give a verbal number response to an approximate presentation (i.e., after seeing rapidly flashed dots, or watching rapid hand taps), and a Word-to-ANS task, where they had to generate an approximate response to a verbal number request (i.e., rapidly tapping after hearing a number word). Replicating previous results, children did not successfully generate numerically appropriate verbal responses in the ANS-to-Word task until after 4 years of age--well after they had acquired the Cardinality Principle of verbal counting. In contrast, children successfully generated numerically appropriate tapping sequences in the Word-to-ANS task before 4 years of age--well before many understood the Cardinality Principle. We further found that the accuracy of the mapping between the ANS and number words, as captured by error rates, continues to develop after this initial formation of the interface. These results suggest that the mapping between the ANS and verbal number representations is not functionally bidirectional in early development, and that the mapping direction from number representations to the ANS is established before the reverse. Copyright © 2015 Elsevier B.V. All rights reserved.

  17. On Fibonacci Numbers Which Are Elliptic Korselt Numbers

    Science.gov (United States)

    2014-11-17

    On Fibonacci numbers which are elliptic Korselt numbers Florian Luca School of Mathematics University of the Witwatersrand P. O. Box Wits 2050, South...is a CM elliptic curve with CM field Q( √ −d), then the set of n for which the nth Fibonacci number Fn satisfies an elliptic Korselt criterion for Q...Directorate for Information Operations and Reports, 1215 Jefferson Davis Highway, Suite 1204, Arlington VA 22202-4302. Respondents should be aware that

  18. Photon number projection using non-number-resolving detectors

    International Nuclear Information System (INIS)

    Rohde, Peter P; Webb, James G; Huntington, Elanor H; Ralph, Timothy C

    2007-01-01

    Number-resolving photo-detection is necessary for many quantum optics experiments, especially in the application of entangled state preparation. Several schemes have been proposed for approximating number-resolving photo-detection using non-number-resolving detectors. Such techniques include multi-port detection and time-division multiplexing. We provide a detailed analysis and comparison of different number-resolving detection schemes, with a view to creating a useful reference for experimentalists. We show that the ideal architecture for projective measurements is a function of the detector's dark count and efficiency parameters. We also describe a process for selecting an appropriate topology given actual experimental component parameters

  19. Bernoulli numbers and zeta functions

    CERN Document Server

    Arakawa, Tsuneo; Kaneko, Masanobu

    2014-01-01

    Two major subjects are treated in this book. The main one is the theory of Bernoulli numbers and the other is the theory of zeta functions. Historically, Bernoulli numbers were introduced to give formulas for the sums of powers of consecutive integers. The real reason that they are indispensable for number theory, however, lies in the fact that special values of the Riemann zeta function can be written by using Bernoulli numbers. This leads to more advanced topics, a number of which are treated in this book: Historical remarks on Bernoulli numbers and the formula for the sum of powers of consecutive integers; a formula for Bernoulli numbers by Stirling numbers; the Clausen–von Staudt theorem on the denominators of Bernoulli numbers; Kummer's congruence between Bernoulli numbers and a related theory of p-adic measures; the Euler–Maclaurin summation formula; the functional equation of the Riemann zeta function and the Dirichlet L functions, and their special values at suitable integers; various formulas of ...

  20. Compendium of Experimental Cetane Numbers

    Energy Technology Data Exchange (ETDEWEB)

    Yanowitz, Janet [Ecoengineering, Sharonville, OH (United States); Ratcliff, Matthew A. [National Renewable Energy Lab. (NREL), Golden, CO (United States); McCormick, Robert L. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Taylor, J. D. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Murphy, M. J. [Battelle, Columbus, OH (United States)

    2017-02-22

    This report is an updated version of the 2014 Compendium of Experimental Cetane Number Data and presents a compilation of measured cetane numbers for pure chemical compounds. It includes all available single-compound cetane number data found in the scientific literature up until December 2016 as well as a number of previously unpublished values, most measured over the past decade at the National Renewable Energy Laboratory. This version of the compendium contains cetane values for 496 pure compounds, including 204 hydrocarbons and 292 oxygenates. 176 individual measurements are new to this version of the compendium, all of them collected using ASTM Method D6890, which utilizes an Ignition Quality Tester (IQT) a type of constant-volume combustion chamber. For many compounds, numerous measurements are included, often collected by different researchers using different methods. The text of this document is unchanged from the 2014 version, except for the numbers of compounds in Section 3.1, the Appendices, Table 1. Primary Cetane Number Data Sources and Table 2. Number of Measurements Included in Compendium. Cetane number is a relative ranking of a fuel's autoignition characteristics for use in compression ignition engines. It is based on the amount of time between fuel injection and ignition, also known as ignition delay. The cetane number is typically measured either in a single-cylinder engine or a constant-volume combustion chamber. Values in the previous compendium derived from octane numbers have been removed and replaced with a brief analysis of the correlation between cetane numbers and octane numbers. The discussion on the accuracy and precision of the most commonly used methods for measuring cetane number has been expanded, and the data have been annotated extensively to provide additional information that will help the reader judge the relative reliability of individual results.

  1. THE RELATIONSHIP BETWEEN NUMBER NAMES AND NUMBER CONCEPTS

    DEFF Research Database (Denmark)

    Ejersbo, Lisser Rye; Misfeldt, Morten

    2016-01-01

    Different countries have different names for numbers. These names are often related in a regular way to the base-10 place value system used for writing numbers as digits. However, in several languages, this regularity breaks down (e.g., between 10 and 20), and there is limited knowledge of how...

  2. Reprint Series: Prime Numbers and Perfect Numbers. RS-2.

    Science.gov (United States)

    Schaaf, William L., Ed.

    This is one in a series of SMSG supplementary and enrichment pamphlets for high school students. This series makes available expository articles which appeared in a variety of mathematical periodicals. Topics covered include: (1) the prime numbers; (2) mathematical sieves; (3) the factorgram; and (4) perfect numbers. (MP)

  3. chromatic number of a complete balanced multipartite graph

    African Journals Online (AJOL)

    In this paper we solve (approximately) the problem of finding the minimum number of colours with which the vertices of a complete, balanced, multipartite graph G may be coloured such that the maximum degrees of all colour class induced subgraphs are at most some specified integer d 2 N. The minimum number of ...

  4. Dynamic Virtual Credit Card Numbers

    Science.gov (United States)

    Molloy, Ian; Li, Jiangtao; Li, Ninghui

    Theft of stored credit card information is an increasing threat to e-commerce. We propose a dynamic virtual credit card number scheme that reduces the damage caused by stolen credit card numbers. A user can use an existing credit card account to generate multiple virtual credit card numbers that are either usable for a single transaction or are tied with a particular merchant. We call the scheme dynamic because the virtual credit card numbers can be generated without online contact with the credit card issuers. These numbers can be processed without changing any of the infrastructure currently in place; the only changes will be at the end points, namely, the card users and the card issuers. We analyze the security requirements for dynamic virtual credit card numbers, discuss the design space, propose a scheme using HMAC, and prove its security under the assumption the underlying function is a PRF.

  5. Nonliteral understanding of number words.

    Science.gov (United States)

    Kao, Justine T; Wu, Jean Y; Bergen, Leon; Goodman, Noah D

    2014-08-19

    One of the most puzzling and important facts about communication is that people do not always mean what they say; speakers often use imprecise, exaggerated, or otherwise literally false descriptions to communicate experiences and attitudes. Here, we focus on the nonliteral interpretation of number words, in particular hyperbole (interpreting unlikely numbers as exaggerated and conveying affect) and pragmatic halo (interpreting round numbers imprecisely). We provide a computational model of number interpretation as social inference regarding the communicative goal, meaning, and affective subtext of an utterance. We show that our model predicts humans' interpretation of number words with high accuracy. Our model is the first to our knowledge to incorporate principles of communication and empirically measured background knowledge to quantitatively predict hyperbolic and pragmatic halo effects in number interpretation. This modeling framework provides a unified approach to nonliteral language understanding more generally.

  6. Number-unconstrained quantum sensing

    Science.gov (United States)

    Mitchell, Morgan W.

    2017-12-01

    Quantum sensing is commonly described as a constrained optimization problem: maximize the information gained about an unknown quantity using a limited number of particles. Important sensors including gravitational wave interferometers and some atomic sensors do not appear to fit this description, because there is no external constraint on particle number. Here, we develop the theory of particle-number-unconstrained quantum sensing, and describe how optimal particle numbers emerge from the competition of particle-environment and particle-particle interactions. We apply the theory to optical probing of an atomic medium modeled as a resonant, saturable absorber, and observe the emergence of well-defined finite optima without external constraints. The results contradict some expectations from number-constrained quantum sensing and show that probing with squeezed beams can give a large sensitivity advantage over classical strategies when each is optimized for particle number.

  7. Bell numbers, determinants and series

    Indian Academy of Sciences (India)

    k=0. (−1)k S(n, k). The usual generating functions for Bell numbers and complementary Bell numbers are given by. ∞. ∑ n=0. Bn tn n! = eet −1 and. ∞. ∑ n=0. ˜Bn tn n! = e−et +1. Stirling numbers can .... + 1) + gn−1(m − 1) = mn−1 + Bn(−1)n. Since there are infinitely many such m the required polynomial recurrence follows.

  8. Familial sinistrals avoid exact numbers.

    Directory of Open Access Journals (Sweden)

    Uli Sauerland

    Full Text Available We report data from an internet questionnaire of sixty number trivia. Participants were asked for the number of cups in their house, the number of cities they know and 58 other quantities. We compare the answers of familial sinistrals--individuals who are left-handed themselves or have a left-handed close blood-relative--with those of pure familial dextrals--right-handed individuals who reported only having right-handed close blood-relatives. We show that familial sinistrals use rounder numbers than pure familial dextrals in the survey responses. Round numbers in the decimal system are those that are multiples of powers of 10 or of half or a quarter of a power of 10. Roundness is a gradient concept, e.g. 100 is rounder than 50 or 200. We show that very round number like 100 and 1000 are used with 25% greater likelihood by familial sinistrals than by pure familial dextrals, while pure familial dextrals are more likely to use less round numbers such as 25, 60, and 200. We then use Sigurd's (1988, Language in Society index of the roundness of a number and report that familial sinistrals' responses are significantly rounder on average than those of pure familial dextrals. To explain the difference, we propose that the cognitive effort of using exact numbers is greater for the familial sinistral group because their language and number systems tend to be more distributed over both hemispheres of the brain. Our data support the view that exact and approximate quantities are processed by two separate cognitive systems. Specifically, our behavioral data corroborates the view that the evolutionarily older, approximate number system is present in both hemispheres of the brain, while the exact number system tends to be localized in only one hemisphere.

  9. Delannoy numbers and Legendre polytopes

    OpenAIRE

    Hetyei, Gábor

    2008-01-01

    International audience; We construct an $n$-dimensional polytope whose boundary complex is compressed and whose face numbers for any pulling triangulation are the coefficients of the powers of $(x-1)/2$ in the $n$-th Legendre polynomial. We show that the non-central Delannoy numbers count all faces in the lexicographic pulling triangulation that contain a point in a given open quadrant. We thus provide a geometric interpretation of a relation between the central Delannoy numbers and Legendre ...

  10. Some Generalized Harmonic Number Identities

    OpenAIRE

    Kronenburg, Maarten

    2011-01-01

    Summation by parts is used to find the sum of a finite series of generalized harmonic numbers involving a specific polynomial or rational function. The Euler-Maclaurin formula for sums of powers is used to find the sums of some finite series of generalized harmonic numbers involving nonnegative integer powers, which can be used to evaluate the sums of the finite series of generalized harmonic numbers involving polynomials. Many examples and a computer program are provided.

  11. Learning Potentials in Number Blocks

    DEFF Research Database (Denmark)

    Majgaard, Gunver; Misfeldt, Morten; Nielsen, Jacob

    2012-01-01

    . The tool is called Number Blocks and it combines physical interaction, learning, and immediate feedback. Number Blocks supports the children's understanding of place value in the sense that it allows them to experiment with creating large numbers. We found the blocks contributed to the learning process...... in several ways. The blocks combined mathematics and play, and they included and supported children at different academic levels. The auditory representation, especially the enhanced rhythmic effects due to using speech synthesis, and the rhythm helped the children to pronounce large numbers. This creates...

  12. A Research on a Certain Family of Numbers and Polynomials Related to Stirling Numbers, Central Factorial Numbers, and Euler Numbers

    Directory of Open Access Journals (Sweden)

    J. Y. Kang

    2013-01-01

    Full Text Available Recently, many mathematicians have studied different kinds of the Euler, Bernoulli, and Genocchi numbers and polynomials. In this paper, we give another definition of polynomials Ũn(x. We observe an interesting phenomenon of “scattering” of the zeros of the polynomials Ũn(x in complex plane. We find out some identities and properties related to polynomials Ũn(x. Finally, we also derive interesting relations between polynomials Ũn(x, Stirling numbers, central factorial numbers, and Euler numbers.

  13. Random number generation and creativity.

    Science.gov (United States)

    Bains, William

    2008-01-01

    A previous paper suggested that humans can generate genuinely random numbers. I tested this hypothesis by repeating the experiment with a larger number of highly numerate subjects, asking them to call out a sequence of digits selected from 0 through 9. The resulting sequences were substantially non-random, with an excess of sequential pairs of numbers and a deficit of repeats of the same number, in line with previous literature. However, the previous literature suggests that humans generate random numbers with substantial conscious effort, and distractions which reduce that effort reduce the randomness of the numbers. I reduced my subjects' concentration by asking them to call out in another language, and with alcohol - neither affected the randomness of their responses. This suggests that the ability to generate random numbers is a 'basic' function of the human mind, even if those numbers are not mathematically 'random'. I hypothesise that there is a 'creativity' mechanism, while not truly random, provides novelty as part of the mind's defence against closed programming loops, and that testing for the effects seen here in people more or less familiar with numbers or with spontaneous creativity could identify more features of this process. It is possible that training to perform better at simple random generation tasks could help to increase creativity, through training people to reduce the conscious mind's suppression of the 'spontaneous', creative response to new questions.

  14. Optimal number of pigments in photosynthetic complexes

    International Nuclear Information System (INIS)

    Jesenko, Simon; Žnidarič, Marko

    2012-01-01

    We study excitation energy transfer in a simple model of a photosynthetic complex. The model, described by the Lindblad equation, consists of pigments interacting via dipole–dipole interaction. The overlapping of pigments induces an on-site energy disorder, providing a mechanism for blocking the excitation transfer. Based on the average efficiency as well as the robustness of random configurations of pigments, we calculate the optimal number of pigments that should be enclosed in a pigment–protein complex of a given size. The results suggest that a large fraction of pigment configurations are efficient as well as robust if the number of pigments is properly chosen. We compare the optimal results of the model to the structure of pigment–protein complexes as found in nature, finding good agreement. (paper)

  15. Experimental study of heat transfer for parallel flow in tube bundles with constant heat flux and for medium Prandtl numbers; Etude experimentale du transfert de chaleur dans des faisceaux tubulaires en ecoulement parallele pour une densite de flux thermique constante dans le domaine des nombres de Prandtl moyens

    Energy Technology Data Exchange (ETDEWEB)

    Rieger, M. [Commissariat a l' Energie Atomique, 91 - Saclay (France). Centre d' Etudes Nucleaires

    1968-06-01

    The heat transfer parameters were determined experimentally in electrically heated tube bundles for turbulent flow parallel to the axis. The tubes were arranged in a pattern of equilateral triangles. The ratios of the distance between the axes of the tubes to their external diameter were 1.60 and 1.25 in the two test sections studied. The experiments were carried out with distilled water and with a mixture of 60 per cent ethylene glycol and 40 per cent water. The values obtained for the Prandtl numbers in this way fell within the range from 2.3 to 18. The Reynolds numbers were varied between 10{sup 4} and 2.10{sup 5}. The relation between the mean heat transfer coefficients and the friction factor in the tube bundles was found from the experiments as: Nu = [Re Pr {zeta}/8]/[1+{radical}({zeta}/8) 8.8 (Pr-1.3) Pr{sup -0.22}]. The experimentally determined mean Nusselt numbers were also given by the following function: Nu = (0.0122 + 0.00245 p/d) Re{sup 0.86} Pr{sup 0.4}, with a maximum deviation of {+-}4 per cent. For certain local Nusselt numbers, deviations of up to 20 per cent with respect to the relations given were observed. (author) [French] Dans des faisceaux tubulaires a chauffage electrique parcourus par un ecoulement turbulent parallele a l'axe, on a determine experimentalement les parametres du transfert de chaleur. Les centres des sections droites des tubes etaient des sommets de triangles equilateraux. Les rapports de la distance a l'axe des tubes et leur diametre exterieur dans les deux veines de mesure etudiees etaient de 1.60 et 1.25. Des essais furent effectues avec de l'eau distillee ainsi qu'avec un melange de 60 pour cent de glycol ethylenique et 40 pour cent d'eau. Les valeurs des nombres de Prandtl obtenues ainsi etaient situees entre 2.3 a 18. On a fait varier les nombres de Reynolds entre 10{sup 4} et 2.10{sup 5}. La relation entre les nombres caracteristiques de transfert de chaleur moyens et la perte de charge dans

  16. The Algebra of Complex Numbers.

    Science.gov (United States)

    LePage, Wilbur R.

    This programed text is an introduction to the algebra of complex numbers for engineering students, particularly because of its relevance to important problems of applications in electrical engineering. It is designed for a person who is well experienced with the algebra of real numbers and calculus, but who has no experience with complex number…

  17. Counting copy number and calories.

    Science.gov (United States)

    White, Stefan

    2015-08-01

    Copy number variation (CNV) at several genomic loci has been associated with different human traits and diseases, but in many cases the findings could not be replicated. A new study provides insights into the degree of variation present at the amylase locus and calls into question a previous association between amylase copy number and body mass index.

  18. Generalized r-Lah numbers

    Indian Academy of Sciences (India)

    generalize earlier identities given for the r-Lah and r-Stirling numbers. We also pro- vide combinatorial proofs of some earlier identities involving the r-Lah numbers by defining appropriate sign-changing involutions. Generalizing these arguments yields orthogonality-type relations that are satisfied by Ga,b(n, k; r). Keywords.

  19. Number theory and its history

    CERN Document Server

    Ore, Oystein

    1988-01-01

    A prominent mathematician presents the principal ideas and methods of number theory within a historical and cultural framework. Oystein Ore's fascinating, accessible treatment requires only a basic knowledge of algebra. Topics include prime numbers, the Aliquot parts, linear indeterminate problems, congruences, Euler's theorem, classical construction problems, and many other subjects.

  20. On the Three Primordial Numbers

    NARCIS (Netherlands)

    Gobbetti, Roberto; Pajer, Enrico; Roest, Diederik

    2015-01-01

    Cosmological observations have provided us with the measurement of just three numbers that characterize the very early universe: $ 1-n_{s} $, $ N $ and $\\ln\\Delta_R^2$. Although each of the three numbers individually carries limited information about the physics of inflation, one may hope to extract

  1. Pseudo-Random Number Generators

    Science.gov (United States)

    Howell, L. W.; Rheinfurth, M. H.

    1984-01-01

    Package features comprehensive selection of probabilistic distributions. Monte Carlo simulations resorted to whenever systems studied not amenable to deterministic analyses or when direct experimentation not feasible. Random numbers having certain specified distribution characteristic integral part of simulations. Package consists of collector of "pseudorandom" number generators for use in Monte Carlo simulations.

  2. Core Knowledge, Language, and Number

    Science.gov (United States)

    Spelke, Elizabeth S.

    2017-01-01

    The natural numbers may be our simplest, most useful, and best-studied abstract concepts, but their origins are debated. I consider this debate in the context of the proposal, by Gallistel and Gelman, that natural number system is a product of cognitive evolution and the proposal, by Carey, that it is a product of human cultural history. I offer a…

  3. Investigating the Randomness of Numbers

    Science.gov (United States)

    Pendleton, Kenn L.

    2009-01-01

    The use of random numbers is pervasive in today's world. Random numbers have practical applications in such far-flung arenas as computer simulations, cryptography, gambling, the legal system, statistical sampling, and even the war on terrorism. Evaluating the randomness of extremely large samples is a complex, intricate process. However, the…

  4. Path-fan Ramsey numbers

    NARCIS (Netherlands)

    Salman, M.; Broersma, Haitze J.

    2003-01-01

    For two given graphs $G$ and $H$, the Ramsey number $R(G,H)$ is the smallest positive integer $p$ such that for every graph $F$ on $p$ vertices the following holds: either $F$ contains $G$ as a subgraph or the complement of $F$ contains $H$ as a subgraph. In this paper, we study the Ramsey numbers

  5. Path-fan Ramsey numbers

    NARCIS (Netherlands)

    Salman, M.; Broersma, Haitze J.

    For two given graphs $F$ and $H$, the Ramsey number $R(F,H)$ is the smallest positive integer $p$ such that for every graph $G$ on $p$ vertices the following holds: either $G$ contains $F$ as a subgraph or the complement of $G$ contains $H$ as a subgraph. In this paper, we study the Ramsey numbers

  6. Path-kipas Ramsey numbers

    NARCIS (Netherlands)

    Salman, M.; Broersma, Haitze J.

    2007-01-01

    For two given graphs $F$ and $H$, the Ramsey number $R(F,H)$ is the smallest positive integer $p$ such that for every graph $G$ on $p$ vertices the following holds: either $G$ contains $F$ as a subgraph or the complement of $G$ contains $H$ as a subgraph. In this paper, we study the Ramsey numbers

  7. From natural numbers to quaternions

    CERN Document Server

    Kramer, Jürg

    2017-01-01

    This textbook offers an invitation to modern algebra through number systems of increasing complexity, beginning with the natural numbers and culminating with Hamilton's quaternions. Along the way, the authors carefully develop the necessary concepts and methods from abstract algebra: monoids, groups, rings, fields, and skew fields. Each chapter ends with an appendix discussing related topics from algebra and number theory, including recent developments reflecting the relevance of the material to current research. The present volume is intended for undergraduate courses in abstract algebra or elementary number theory. The inclusion of exercises with solutions also makes it suitable for self-study and accessible to anyone with an interest in modern algebra and number theory.

  8. Gauged baryon and lepton numbers

    International Nuclear Information System (INIS)

    Foot, R.; Joshi, G.C.; Lew, H.

    1989-01-01

    A possible extension of the Standard Model can be defined by gauging the global baryon and lepton number U(1) symmetries. Gauging baryon and lepton numbers provide a natural framework for the see-saw mechanism in the lepton sector, and the Peccei-Quinn mechanism in the quark sector. Another consequence of this extension is that the usual three generations of fermions are not anomaly free. However the authors consider a wider framework involving the existence of generations with exotic SU(2) L tensor product U(1) Y quantum numbers. This allows them to derive a minimal spectrum of fermions which contain the known quarks and leptons. 12 refs

  9. Fundamental number theory with applications

    CERN Document Server

    Mollin, Richard A

    2008-01-01

    An update of the most accessible introductory number theory text available, Fundamental Number Theory with Applications, Second Edition presents a mathematically rigorous yet easy-to-follow treatment of the fundamentals and applications of the subject. The substantial amount of reorganizing makes this edition clearer and more elementary in its coverage. New to the Second Edition           Removal of all advanced material to be even more accessible in scope           New fundamental material, including partition theory, generating functions, and combinatorial number theory           Expa

  10. Number theory via Representation theory

    Indian Academy of Sciences (India)

    2014-11-09

    Number theory via Representation theory. Eknath Ghate. November 9, 2014. Eightieth Annual Meeting, Chennai. Indian Academy of Sciences1. 1. This is a non-technical 20 minute talk intended for a general Academy audience.

  11. Baryogenesis through lepton number violation

    CERN Document Server

    Sarkar, U

    1998-01-01

    The most promising scenarios of baryogenesis seems to be the one through lepton number violation. Lepton number violation through a Majarana mass of the right-handed neutrinos can generate a lepton asymmetry of the universe when the right-handed neutrinos decay. The left-handed neutrinos get small Majorana masses through see-saw mechanism in these models. A triplet higgs scalar violating lepton number explicitly through its couplings to two leptons or two higgs doublets can also naturally give small Majorana masses to the left-handed neutrinos and also generate a lepton asymmetry of the universe. We review both these models of leptogenesis, where the lepton number asymmetry then gets converted to a baryon asymmetry of the universe before the electroweak phase transition.

  12. Women In Numbers - Europe workshop

    CERN Document Server

    Bucur, Alina; Feigon, Brooke; Schneps, Leila

    2015-01-01

    Covering topics in graph theory, L-functions, p-adic geometry, Galois representations, elliptic fibrations, genus 3 curves and bad reduction, harmonic analysis, symplectic groups and mould combinatorics, this volume presents a collection of papers covering a wide swath of number theory emerging from the third iteration of the international Women in Numbers conference, “Women in Numbers - Europe” (WINE), held on October 14–18, 2013 at the CIRM-Luminy mathematical conference center in France. While containing contributions covering a wide range of cutting-edge topics in number theory, the volume emphasizes those concrete approaches that make it possible for graduate students and postdocs to begin work immediately on research problems even in highly complex subjects.

  13. SEVIS By the Numbers 2014

    Data.gov (United States)

    Department of Homeland Security — SEVIS by the Numbers is a quarterly report that highlights nonimmigrant student and exchange visitor trends, values and information using data from the Student and...

  14. Advanced number theory with applications

    CERN Document Server

    Mollin, Richard A

    2009-01-01

    Algebraic Number Theory and Quadratic Fields Algebraic Number Fields The Gaussian Field Euclidean Quadratic Fields Applications of Unique Factorization Ideals The Arithmetic of Ideals in Quadratic Fields Dedekind Domains Application to Factoring Binary Quadratic Forms Basics Composition and the Form Class Group Applications via Ambiguity Genus Representation Equivalence Modulo p Diophantine Approximation Algebraic and Transcendental Numbers Transcendence Minkowski's Convex Body Theorem Arithmetic Functions The Euler-Maclaurin Summation Formula Average Orders The Riemann zeta-functionIntroduction to p-Adic AnalysisSolving Modulo pn Introduction to Valuations Non-Archimedean vs. Archimedean Valuations Representation of p-Adic NumbersDirichlet: Characters, Density, and Primes in Progression Dirichlet Characters Dirichlet's L-Function and Theorem Dirichlet DensityApplications to Diophantine Equations Lucas-Lehmer Theory Generalized Ramanujan-Nagell Equations Bachet's Equation The Fermat Equation Catalan and the A...

  15. From Calculus to Number Theory

    Indian Academy of Sciences (India)

    A. Raghuram

    2016-11-04

    Nov 4, 2016 ... General L-functions. There are various mathematical objects M that determine, and are determined, by a sequence an = an(M). A general principle in number theory: study M by studying: ...

  16. Numbers their history and meaning

    CERN Document Server

    Flegg, Graham

    2003-01-01

    Readable, jargon-free book examines the earliest endeavors to count and record numbers, initial attempts to solve problems by using equations, and origins of infinite cardinal arithmetic. "Surprisingly exciting." - Choice.

  17. Poison control center - emergency number

    Science.gov (United States)

    For a POISON EMERGENCY call: 1-800-222-1222 ANYWHERE IN THE UNITED STATES This national hotline number will let you ... is a free and confidential service. All local poison control centers in the United States use this ...

  18. SEVIS By the Numbers 2016

    Data.gov (United States)

    Department of Homeland Security — SEVIS by the Numbers is a quarterly report that highlights nonimmigrant student and exchange visitor trends, values and information using data from the Student and...

  19. Classical theory of algebraic numbers

    CERN Document Server

    Ribenboim, Paulo

    2001-01-01

    Gauss created the theory of binary quadratic forms in "Disquisitiones Arithmeticae" and Kummer invented ideals and the theory of cyclotomic fields in his attempt to prove Fermat's Last Theorem These were the starting points for the theory of algebraic numbers, developed in the classical papers of Dedekind, Dirichlet, Eisenstein, Hermite and many others This theory, enriched with more recent contributions, is of basic importance in the study of diophantine equations and arithmetic algebraic geometry, including methods in cryptography This book has a clear and thorough exposition of the classical theory of algebraic numbers, and contains a large number of exercises as well as worked out numerical examples The Introduction is a recapitulation of results about principal ideal domains, unique factorization domains and commutative fields Part One is devoted to residue classes and quadratic residues In Part Two one finds the study of algebraic integers, ideals, units, class numbers, the theory of decomposition, iner...

  20. Microcomputer Unit: Generating Random Numbers.

    Science.gov (United States)

    Haigh, William E.

    1986-01-01

    Presents an activity, suitable for students in grades 6-12, on generating random numbers. Objectives, equipment needed, list of prerequisite experiences, instructional strategies, and ready-to-copy student worksheets are included. (JN)

  1. Social Security Number (SSN) Verification

    Data.gov (United States)

    U.S. Department of Health & Human Services — This report presents the results of a validation study of Social Security numbers (SSNs) in Medicaid Statistical Information System (MSIS) records for the fourth...

  2. Subject-verb number (disagreement

    Directory of Open Access Journals (Sweden)

    Daniela Isac

    2010-01-01

    Full Text Available This paper discusses cases of number mismatches between subjects and verbs. The main proposal is that subject-verb agreement is not in number but in a different feature, that we call Cardinality. Cardinality is a feature of DPs that is computed on the basis of number features and collectivity features carried by various heads in the DP. The “computation” of the Cardinality feature proceeds internal to the feature matrix of one lexical item - the D. The values of the number and collectivity features carried by various heads in the DP are transferred to the D by means of a feature checking mechanism and the value of the Cardinality feature is then derived from these.

  3. Numbers for reducible cubic scrolls

    Directory of Open Access Journals (Sweden)

    Israel Vainsencher

    2004-12-01

    Full Text Available We show how to compute the number of reducible cubic scrolls of codimension 2 in (math blackboard symbol Pn incident to the appropriate number of linear spaces.Mostramos como calcular o número de rolos cúbicos redutíveis de codimensão 2 em (math blackboard symbol Pn incidentes a espaços lineares apropriados.

  4. Digital random-number generator

    Science.gov (United States)

    Brocker, D. H.

    1973-01-01

    For binary digit array of N bits, use N noise sources to feed N nonlinear operators; each flip-flop in digit array is set by nonlinear operator to reflect whether amplitude of generator which feeds it is above or below mean value of generated noise. Fixed-point uniform distribution random number generation method can also be used to generate random numbers with other than uniform distribution.

  5. Random numbers from vacuum fluctuations

    International Nuclear Information System (INIS)

    Shi, Yicheng; Kurtsiefer, Christian; Chng, Brenda

    2016-01-01

    We implement a quantum random number generator based on a balanced homodyne measurement of vacuum fluctuations of the electromagnetic field. The digitized signal is directly processed with a fast randomness extraction scheme based on a linear feedback shift register. The random bit stream is continuously read in a computer at a rate of about 480 Mbit/s and passes an extended test suite for random numbers.

  6. Banner prints social security numbers

    OpenAIRE

    Robbins RA

    2014-01-01

    No abstract available. Article truncated at 150 words. The Monday edition of the Arizona Republic contained a story with potential interest to our readers. On the most recent address labels of Banner Health's magazine, Smart & Healthy, the addressee's Social Security or Medicare identification numbers, which are often identical to their Social Security numbers (1). The magazine was mailed to more than 50,000 recipients in Arizona late last week. The recipients are members of the Medicare Pion...

  7. Lepton number violation in theories with a large number of standard model copies

    International Nuclear Information System (INIS)

    Kovalenko, Sergey; Schmidt, Ivan; Paes, Heinrich

    2011-01-01

    We examine lepton number violation (LNV) in theories with a saturated black hole bound on a large number of species. Such theories have been advocated recently as a possible solution to the hierarchy problem and an explanation of the smallness of neutrino masses. On the other hand, the violation of the lepton number can be a potential phenomenological problem of this N-copy extension of the standard model as due to the low quantum gravity scale black holes may induce TeV scale LNV operators generating unacceptably large rates of LNV processes. We show, however, that this issue can be avoided by introducing a spontaneously broken U 1(B-L) . Then, due to the existence of a specific compensation mechanism between contributions of different Majorana neutrino states, LNV processes in the standard model copy become extremely suppressed with rates far beyond experimental reach.

  8. From Natural Numbers to Numbers and Curves in Nature - II

    Indian Academy of Sciences (India)

    sunflowers have 34, 55 or 89 petals. If one carefully observes the row of scales on the surface of a pineapple, then these diamond shaped marks are seen to follow two spirals sloping in opposite directions. It is found that the helix angles of these two spirals are different. If one counts the numbers of these marks along these.

  9. Are Number Gestures Easier than Number Words for Preschoolers?

    Science.gov (United States)

    Nicoladis, Elena; Pika, Simone; Marentette, Paula

    2010-01-01

    Some researchers have argued that children's earliest symbols are based on their sensorimotor experience and that arbitrary symbol-referent mapping poses a challenge for them. If so, exposure to iconic symbols (such as one-finger-for-one-object manual gestures) might help children in a difficult domain such as number. We assessed 44 preschoolers'…

  10. Number Meaning and Number Grammar in English and Spanish

    Science.gov (United States)

    Bock, Kathryn; Carreiras, Manuel; Meseguer, Enrique

    2012-01-01

    Grammatical agreement makes different demands on speakers of different languages. Being widespread in the languages of the world, the features of agreement systems offer valuable tests of how language affects deep-seated domains of human cognition and categorization. Number agreement is one such domain, with intriguing evidence that typological…

  11. Searching for the highest number.

    Science.gov (United States)

    Howe, Piers D L; Little, Daniel R

    2015-02-01

    When viewing a collection of products how does a consumer decide which one to buy? To do this task, the consumer not only needs to evaluate the desirability of the products, taking into account factors such as quality and price, but also needs to search through the products to find the most desirable one. We studied the search process using an abstraction of a common consumer choice task. In our task, observers searched an array of numbers for the highest. Crucially, the observers did not know in advance what this number would be, which made it difficult to know when the search should be terminated. In this way, our search task mimicked a problem often faced by consumers in a supermarket setting where they also may not know in advance what the most desirable product will be. We compared several computational models. We found that our data was best described by a process that assumes that observers terminate their search when they find a number that exceeds an internal threshold. Depending on the observer and the circumstances, this threshold appeared either to be fixed or to decrease over the course of the trial. This threshold can explain why in some situations the observers terminate the search without inspecting all the numbers in the display, whereas in other situations observers act in a seemingly irrational manner, continuing the search even after inspecting all the numbers.

  12. The MIXMAX random number generator

    Science.gov (United States)

    Savvidy, Konstantin G.

    2015-11-01

    In this paper, we study the randomness properties of unimodular matrix random number generators. Under well-known conditions, these discrete-time dynamical systems have the highly desirable K-mixing properties which guarantee high quality random numbers. It is found that some widely used random number generators have poor Kolmogorov entropy and consequently fail in empirical tests of randomness. These tests show that the lowest acceptable value of the Kolmogorov entropy is around 50. Next, we provide a solution to the problem of determining the maximal period of unimodular matrix generators of pseudo-random numbers. We formulate the necessary and sufficient condition to attain the maximum period and present a family of specific generators in the MIXMAX family with superior performance and excellent statistical properties. Finally, we construct three efficient algorithms for operations with the MIXMAX matrix which is a multi-dimensional generalization of the famous cat-map. First, allowing to compute the multiplication by the MIXMAX matrix with O(N) operations. Second, to recursively compute its characteristic polynomial with O(N2) operations, and third, to apply skips of large number of steps S to the sequence in O(N2 log(S)) operations.

  13. World Epidemiology Review, Number 78

    Science.gov (United States)

    1977-01-13

    34malaria parasite" to determine the resistance capacity of standard drugs on it and to prescribe alternative drugs. The delegates agreed on...concentrated research. Resistance of the malaria parasite to drugs is an urgent research problem. Attempts are being made to develop a vaccine...some 30 persons afflicted with scabies and other skin ailments (including burns) to be cured and have induced rapid healing of leprosy lesions in 7 to

  14. Experimental determination of Ramsey numbers.

    Science.gov (United States)

    Bian, Zhengbing; Chudak, Fabian; Macready, William G; Clark, Lane; Gaitan, Frank

    2013-09-27

    Ramsey theory is a highly active research area in mathematics that studies the emergence of order in large disordered structures. Ramsey numbers mark the threshold at which order first appears and are extremely difficult to calculate due to their explosive rate of growth. Recently, an algorithm that can be implemented using adiabatic quantum evolution has been proposed that calculates the two-color Ramsey numbers R(m,n). Here we present results of an experimental implementation of this algorithm and show that it correctly determines the Ramsey numbers R(3,3) and R(m,2) for 4≤m≤8. The R(8,2) computation used 84 qubits of which 28 were computational qubits. This computation is the largest experimental implementation of a scientifically meaningful adiabatic evolution algorithm that has been done to date.

  15. Sequences, groups, and number theory

    CERN Document Server

    Rigo, Michel

    2018-01-01

    This collaborative book presents recent trends on the study of sequences, including combinatorics on words and symbolic dynamics, and new interdisciplinary links to group theory and number theory. Other chapters branch out from those areas into subfields of theoretical computer science, such as complexity theory and theory of automata. The book is built around four general themes: number theory and sequences, word combinatorics, normal numbers, and group theory. Those topics are rounded out by investigations into automatic and regular sequences, tilings and theory of computation, discrete dynamical systems, ergodic theory, numeration systems, automaton semigroups, and amenable groups.  This volume is intended for use by graduate students or research mathematicians, as well as computer scientists who are working in automata theory and formal language theory. With its organization around unified themes, it would also be appropriate as a supplemental text for graduate level courses.

  16. Magic Numbers in Protein Structures

    DEFF Research Database (Denmark)

    Lindgård, Per-Anker; Bohr, Henrik

    1996-01-01

    A homology measure for protein fold classes has been constructed by locally projecting consecutive secondary structures onto a lattice. Taking into account hydrophobic forces we have found a mechanism for formation of domains containing magic numbers of secondary structures and multipla of these ......A homology measure for protein fold classes has been constructed by locally projecting consecutive secondary structures onto a lattice. Taking into account hydrophobic forces we have found a mechanism for formation of domains containing magic numbers of secondary structures and multipla...

  17. Lenstra theorem in number fields

    Indian Academy of Sciences (India)

    Indian Acad. Sci. (Math. Sci.) Vol. 124, No. 4, November 2014, pp. 481– 485. c Indian Academy of Sciences. Lenstra theorem in number fields. S SUBBURAM. Department of Mathematics, SASTRA University, Thanjavur 613 401, India. Present Address: The Institute of Mathematics, CIT Campus, Taramani,. Chennai 600 113 ...

  18. The elephant brain in numbers

    Science.gov (United States)

    Herculano-Houzel, Suzana; Avelino-de-Souza, Kamilla; Neves, Kleber; Porfírio, Jairo; Messeder, Débora; Mattos Feijó, Larissa; Maldonado, José; Manger, Paul R.

    2014-01-01

    What explains the superior cognitive abilities of the human brain compared to other, larger brains? Here we investigate the possibility that the human brain has a larger number of neurons than even larger brains by determining the cellular composition of the brain of the African elephant. We find that the African elephant brain, which is about three times larger than the human brain, contains 257 billion (109) neurons, three times more than the average human brain; however, 97.5% of the neurons in the elephant brain (251 billion) are found in the cerebellum. This makes the elephant an outlier in regard to the number of cerebellar neurons compared to other mammals, which might be related to sensorimotor specializations. In contrast, the elephant cerebral cortex, which has twice the mass of the human cerebral cortex, holds only 5.6 billion neurons, about one third of the number of neurons found in the human cerebral cortex. This finding supports the hypothesis that the larger absolute number of neurons in the human cerebral cortex (but not in the whole brain) is correlated with the superior cognitive abilities of humans compared to elephants and other large-brained mammals. PMID:24971054

  19. Strouhal number for free swimming

    Science.gov (United States)

    Saadat, Mehdi; van Buren, Tyler; Floryan, Daniel; Smits, Alexander; Haj-Hariri, Hossein

    2015-11-01

    In this work, we present experimental results to explore the implications of free swimming for Strouhal number (as an outcome) in the context of a simple model for a fish that consists of a 2D virtual body (source of drag) and a 2D pitching foil (source of thrust) representing cruising with thunniform locomotion. The results validate the findings of Saadat and Haj-Hariri (2012): for pitching foils thrust coefficient is a function of Strouhal number for all gaits having amplitude less than a certain critical value. Equivalently, given the balance of thrust and drag forces at cruise, Strouhal number is only a function of the shape, i.e. drag coefficient and area, and essentially a constant for high enough swimming speeds for which the mild dependence of drag coefficient on the speed vanishes. Furthermore, a dimensional analysis generalizes the findings. A scaling analysis shows that the variation of Strouhal number with cruising speed is functionally related to the variation of body drag coefficient with speed. Supported by ONR MURI Grant N00014-14-1-0533.

  20. A generalized sense of number.

    Science.gov (United States)

    Arrighi, Roberto; Togoli, Irene; Burr, David C

    2014-12-22

    Much evidence has accumulated to suggest that many animals, including young human infants, possess an abstract sense of approximate quantity, a number sense. Most research has concentrated on apparent numerosity of spatial arrays of dots or other objects, but a truly abstract sense of number should be capable of encoding the numerosity of any set of discrete elements, however displayed and in whatever sensory modality. Here, we use the psychophysical technique of adaptation to study the sense of number for serially presented items. We show that numerosity of both auditory and visual sequences is greatly affected by prior adaptation to slow or rapid sequences of events. The adaptation to visual stimuli was spatially selective (in external, not retinal coordinates), pointing to a sensory rather than cognitive process. However, adaptation generalized across modalities, from auditory to visual and vice versa. Adaptation also generalized across formats: adapting to sequential streams of flashes affected the perceived numerosity of spatial arrays. All these results point to a perceptual system that transcends vision and audition to encode an abstract sense of number in space and in time.

  1. Linking numbers and variational method

    International Nuclear Information System (INIS)

    Oda, I.; Yahikozawa, S.

    1989-09-01

    The ordinary and generalized linking numbers for two surfaces of dimension p and n-p-1 in an n dimensional manifold are derived. We use a variational method based on the properties of topological quantum field theory in order to derive them. (author). 13 refs, 2 figs

  2. RELATIONSHIP BETWEEN SLUDGE DEWATERABILITY NUMBER ...

    African Journals Online (AJOL)

    A representative of a sludge sample collected from the same source was filtered under the same environmental condition and the result analysed with two different concepts. One method of analysis uses Sludge Dewaterability Number, while the second employed the Carman's Specific resistance concept in sludge ...

  3. On badly approximable complex numbers

    DEFF Research Database (Denmark)

    Esdahl-Schou, Rune; Kristensen, S.

    We show that the set of complex numbers which are badly approximable by ratios of elements of , where has maximal Hausdorff dimension. In addition, the intersection of these sets is shown to have maximal dimension. The results remain true when the sets in question are intersected with a suitably...

  4. Number theory via Representation theory

    Indian Academy of Sciences (India)

    2014-11-09

    Nov 9, 2014 ... What is known? The answer depends on two quantities: 1. The weight k of f , which is a positive integer ≥ 2. 2. The slope v of f , a positive (rational) number which. (roughly) measures how divisible ap is by p.

  5. An introduction to Catalan numbers

    CERN Document Server

    Roman, Steven

    2015-01-01

    This textbook provides an introduction to the Catalan numbers and their remarkable properties, along with their various applications in combinatorics.  Intended to be accessible to students new to the subject, the book begins with more elementary topics before progressing to more mathematically sophisticated topics.  Each chapter focuses on a specific combinatorial object counted by these numbers, including paths, trees, tilings of a staircase, null sums in Zn+1, interval structures, partitions, permutations, semiorders, and more.  Exercises are included at the end of book, along with hints and solutions, to help students obtain a better grasp of the material.  The text is ideal for undergraduate students studying combinatorics, but will also appeal to anyone with a mathematical background who has an interest in learning about the Catalan numbers. “Roman does an admirable job of providing an introduction to Catalan numbers of a different nature from the previous ones.  He has made an excellent choice o...

  6. World Epidemiology Review, Number 91

    Science.gov (United States)

    1978-02-09

    consequent continuation of the prophylactic vaccination against diphtheria, whoop- ing cough, tetanus, tuberculosis , infantile paralysis and measles...measles, tetanus and infantile tuberculosis . At least 10 million remain physically handicapped. NUMBER OF PHYSICIANS, DENTISTS TO INCREASE East Berlin...general activity in this sphere be further expanded and that deadly diseases such as tuberculosis , typhus, poliomyelitis, and others, be brought under

  7. Materiales. Numbers 17-20.

    Science.gov (United States)

    Materiales, 1995

    1995-01-01

    Four booklets present articles on Spanish language and culture aimed at teachers of Spanish in the United States for student use in their classes. Number 17, "Los Jovenes Espanoles" (Spanish Youth), includes articles on Spanish youth sports, music, gangs, thoughts, and t-shirt slogans: (1) "Young Spanish Athletes"; (2)…

  8. Materiales. Numbers 21-23.

    Science.gov (United States)

    Materiales, 1997

    1997-01-01

    These three journals of contemporary cultural, historical, and social interest contain activities designed to enhance the awareness of students of Spanish as a foreign language regarding the entire panorama of daily life in Spain. Number 21 focuses on the role of modern Spanish women; their career status; female authors; and the changing place of…

  9. Complex Numbers and Plane Geometry

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 13; Issue 1. Complex Numbers and Plane Geometry. Anant R Shastri. General Article Volume 13 Issue 1 January 2008 pp 35-53. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/013/01/0035-0053. Keywords.

  10. Counting problems for number rings

    NARCIS (Netherlands)

    Brakenhoff, Johannes Franciscus

    2009-01-01

    In this thesis we look at three counting problems connected to orders in number fields. First we study the probability that for a random polynomial f in Z[X] the ring Z[X]/f is the maximal order in Q[X]/f. Connected to this is the probability that a random polynomial has a squarefree

  11. 3-D numerical study of the effect of Reynolds number and baffle angle on heat transfer and pressure drop of turbulent flow of air through rectangular duct of very small height

    Directory of Open Access Journals (Sweden)

    Abhijit Paul

    2016-09-01

    Full Text Available Present article illustrates a computational study of three-dimensional steady state heat transfer and high turbulent flow characteristics through a rectangular duct with constant heat fluxed upper wall and single rectangular cross-sectioned baffle insertion at different angles. RNG k–ɛ model along with standard wall function based computations has been accomplished applying the finite volume method, and SIMPLE algorithm has been executed for solving the governing equations. For a Reynolds number, Re of 10,000 to 50,000, Prandtl Number, Pr of 0.707 and baffle angle, α of 30°, 60°, 90°, 120°, 150°, computational studies are executed, centred onto the hydraulic diameter, Dh, test section and hydrodynamic entry length of the duct. Flow field has been solved using Ansys Fluent 14.0 software. Study exposes that baffled rectangular duct has a higher average Nusselt number, Nu and Darcy friction factor, f compared to a smooth rectangular duct. Nu as well as f are found to be maximum at 90° baffle angle. Results illustrate that both α and Re play a significant role in heat transfer as well as flow characteristics and also effects TEF. The correctness of the results attained in this study is corroborated by comparing the results with those existing in the literature for smooth rectangular duct within a precision of ±2% for f and ±4% for Nu.

  12. Intersection numbers of spectral curves

    CERN Document Server

    Eynard, B

    2011-01-01

    We compute the symplectic invariants of an arbitrary spectral curve with only 1 branchpoint in terms of integrals of characteristic classes in the moduli space of curves. Our formula associates to any spectral curve, a characteristic class, which is determined by the laplace transform of the spectral curve. This is a hint to the key role of Laplace transform in mirror symmetry. When the spectral curve is y=\\sqrt{x}, the formula gives Kontsevich--Witten intersection numbers, when the spectral curve is chosen to be the Lambert function \\exp{x}=y\\exp{-y}, the formula gives the ELSV formula for Hurwitz numbers, and when one chooses the mirror of C^3 with framing f, i.e. \\exp{-x}=\\exp{-yf}(1-\\exp{-y}), the formula gives the topological vertex formula, i.e. the generating function of Gromov-Witten invariants of C^3. In some sense this formula generalizes ELSV formula, and Mumford formula.

  13. Gaussian distribution of LMOV numbers

    Directory of Open Access Journals (Sweden)

    A. Mironov

    2017-11-01

    Full Text Available Recent advances in knot polynomial calculus allowed us to obtain a huge variety of LMOV integers counting degeneracy of the BPS spectrum of topological theories on the resolved conifold and appearing in the genus expansion of the plethystic logarithm of the Ooguri–Vafa partition functions. Already the very first look at this data reveals that the LMOV numbers are randomly distributed in genus (! and are very well parameterized by just three parameters depending on the representation, an integer and the knot. We present an accurate formulation and evidence in support of this new puzzling observation about the old puzzling quantities. It probably implies that the BPS states, counted by the LMOV numbers can actually be composites made from some still more elementary objects.

  14. Gaussian distribution of LMOV numbers

    Science.gov (United States)

    Mironov, A.; Morozov, A.; Morozov, An.; Sleptsov, A.

    2017-11-01

    Recent advances in knot polynomial calculus allowed us to obtain a huge variety of LMOV integers counting degeneracy of the BPS spectrum of topological theories on the resolved conifold and appearing in the genus expansion of the plethystic logarithm of the Ooguri-Vafa partition functions. Already the very first look at this data reveals that the LMOV numbers are randomly distributed in genus (!) and are very well parameterized by just three parameters depending on the representation, an integer and the knot. We present an accurate formulation and evidence in support of this new puzzling observation about the old puzzling quantities. It probably implies that the BPS states, counted by the LMOV numbers can actually be composites made from some still more elementary objects.

  15. Generalized r-Lah numbers

    Indian Academy of Sciences (India)

    themselves the smallest element of a block. Let nrec(λ) denote the number of elements of. [n] which are not record lows of λ. To illustrate, if λ is as above, then rec. ∗. (λ) = 2 (for the 8 and 4) and nrec(λ) = 4 (for. 5, 3, 7 and 9). We now consider the restriction of the rec. ∗ and nrec statistics to Lr(n, k) and define the distribution ...

  16. Number theory meets Higgs physics

    CERN Multimedia

    CERN. Geneva

    2014-01-01

    Inspired by results from modern number theory and algebraic geometry, a lot of progress has recently been made regarding the computation of multi-loop integrals and scattering amplitudes. I will discuss various new approaches to the computation of loop integrals, and illustrate them on the first computation of a quantity at N3LO in perturbative QCD, the soft-virtual part of the inclusive Higgs-boson cross section in gluon fusion at N3LO.

  17. On the number of matroids

    NARCIS (Netherlands)

    N. Bansal (Nikhil); R. Pendavingh; J.G. van der Pol (Jorn)

    2013-01-01

    htmlabstractWe consider the problem of determining mn, the number of matroids on n elements. The best known lower bound on mn is due to Knuth (1974) who showed that log log mn is at least n− 3 2 log n−O(1). On the other hand, Piff (1973) showed that log log mn ≤ n − log n + log log n + O(1),

  18. World Epidemiology Review, Number 105.

    Science.gov (United States)

    1978-09-13

    fruit, beverages, and other food items handled by him are likely to get infected. 37 Fruit and vegetables consumed uncooked, such as lettuce ...pure. Cholera bacteria can remain in the folds of lettuce , carrots, radishes, and similar vegetables even when they are carefully washed. It should...numbers of aphids are due to appear on the alfalfa in the near future. The infestation has approached and even exceeded the extent at which serious

  19. Covering Numbers for Semicontinuous Functions

    Science.gov (United States)

    2016-04-29

    Although a comparison to the classical result of O(ε−d) for Lipschitz continuous functions on bounded subsets, which goes back to [17] (see for...Covering Numbers for Semicontinuous Functions Johannes O. Royset Operations Research Department Naval Postgraduate School joroyset@nps.edu Abstract...Considering the metric space of extended real-valued lower semicontinuous functions under the epi-distance, the paper gives an upper bound on the

  20. Secular Love number of Phobos

    International Nuclear Information System (INIS)

    Bursa, M.

    1988-01-01

    The secular Love number of Phobos was estimated k s =10.4. It only deviates by one order of magnitude from that corresponding to the ideal equilibrium state. It is not in contradiction with the theory of the origin of Phobos as a result of the accretion around Mars. In its early history, the rotation period of Phobos had been estimated to be approx. 2.4 hours. (author). 1 tab., 4 refs

  1. More Sets, Graphs and Numbers

    CERN Document Server

    Gyori, Ervin; Lovasz, Laszlo

    2006-01-01

    This volume honours the eminent mathematicians Vera Sos and Andras Hajnal. The book includes survey articles reviewing classical theorems, as well as new, state-of-the-art results. Also presented are cutting edge expository research papers with new theorems and proofs in the area of the classical Hungarian subjects, like extremal combinatorics, colorings, combinatorial number theory, etc. The open problems and the latest results in the papers are sure to inspire further research.

  2. Approximate number sense, symbolic number processing, or number-space mappings: what underlies mathematics achievement?

    Science.gov (United States)

    Sasanguie, Delphine; Göbel, Silke M; Moll, Kristina; Smets, Karolien; Reynvoet, Bert

    2013-03-01

    In this study, the performance of typically developing 6- to 8-year-old children on an approximate number discrimination task, a symbolic comparison task, and a symbolic and nonsymbolic number line estimation task was examined. For the first time, children's performances on these basic cognitive number processing tasks were explicitly contrasted to investigate which of them is the best predictor of their future mathematical abilities. Math achievement was measured with a timed arithmetic test and with a general curriculum-based math test to address the additional question of whether the predictive association between the basic numerical abilities and mathematics achievement is dependent on which math test is used. Results revealed that performance on both mathematics achievement tests was best predicted by how well childrencompared digits. In addition, an association between performance on the symbolic number line estimation task and math achievement scores for the general curriculum-based math test measuring a broader spectrum of skills was found. Together, these results emphasize the importance of learning experiences with symbols for later math abilities. Copyright © 2012 Elsevier Inc. All rights reserved.

  3. Natural convection in a cubical cavity with a coaxial heated cylinder

    Energy Technology Data Exchange (ETDEWEB)

    Aithal, S. M.

    2018-03-01

    High-resolution three-dimensional simulations were conducted to investigate the velocity and temperature fields in a cold cubical cavity due to natural convection induced by a centrally placed hot cylinder. Unsteady, incompressible Navier-Stokes equations were solved by using a spectral- element method for Rayleigh numbers ranging from 103 to 109. The effect of spanwise thermal boundary conditions, aspect ratio (radius of the cylinder to the side of the cavity), and spanwise temperature distribution of the inner cylinder on the velocity and thermal fields were investigated for each Rayleigh number. Results from two-dimensional calculations were compared with three-dimensional simulations. The 3D results indicate a complex flow structure in the vicinity of the spanwise walls. The results also show that the imposed thermal wall boundary condition impacts the flow and temperature fields strongly near the spanwise walls. The variation of the local Nusselt number on the cylinder surface and enclosure walls at various spanwise locations was also investigated. The local Nusselt number on the cylinder surface and enclosure walls at the cavity mid-plane (Z = 0) is close to 2D simulations for 103 ≤ Ra ≤ 108. Simulations also show a variation in the local Nusselt number, on both the cylinder surface and the enclosure walls, in the spanwise direction, for all Rayleigh numbers studied in this work. The results also indicate that if the enclosure walls are insulated in the spanwise direction (as opposed to a constant temperature), the peak Nusselt number on the enclosure surface occurs near the spanwise walls and is about 20% higher than the peak Nusselt number at the cavity mid-plane. The temporal characteristics of 3D flows are also different from 2D results for Ra > 108. These results suggest that 3D simulations would be more appropriate for flows with Ra > 108.

  4. Nielsen number and differential equations

    Directory of Open Access Journals (Sweden)

    Andres Jan

    2005-01-01

    Full Text Available In reply to a problem of Jean Leray (application of the Nielsen theory to differential equations, two main approaches are presented. The first is via Poincaré's translation operator, while the second one is based on the Hammerstein-type solution operator. The applicability of various Nielsen theories is discussed with respect to several sorts of differential equations and inclusions. Links with the Sharkovskii-like theorems (a finite number of periodic solutions imply infinitely many subharmonics are indicated, jointly with some further consequences like the nontrivial -structure of solutions of initial value problems. Some illustrating examples are supplied and open problems are formulated.

  5. On the intriguing number 1001

    DEFF Research Database (Denmark)

    Krarup, Jakob

    2016-01-01

    Born in 1936 I was a schoolboy on the threshold of the secondary school when a knapsack-type game was played with a class mate around 1946–1947. To play the game well and fascinated by numbers in general since my early childhood, however, I realized soon the usefulness of knowing that 1001 = 7 × 11...... × 13. Today, about 70 years later, the game has been passed to some of my grandchildren who also should convince themselves that simple, arithmetic calculations do not necessarily require a pocket computer. As a side effect of the recent revival of the game I felt motivated to seek more insight...

  6. Random number generators and causality

    International Nuclear Information System (INIS)

    Larrondo, H.A.; Martin, M.T.; Gonzalez, C.M.; Plastino, A.; Rosso, O.A.

    2006-01-01

    We advance a prescription to randomize physical or algorithmic Random Number Generators (RNG's) that do not pass Marsaglia's DIEHARD test suite and discuss a special physical quantifier, based on an intensive statistical complexity measure, that is able to adequately assess the improvements produced thereby. Eight RNG's are evaluated and the associated results are compared to those obtained by recourse to Marsaglia's DIEHARD test suite. Our quantifier, which is evaluated using causality arguments, can forecast whether a given RNG will pass the above mentioned test

  7. Propulsion at low Reynolds number

    Energy Technology Data Exchange (ETDEWEB)

    Najafi, Ali [Institute for Advanced Studies in Basic Sciences, Zanjan 45195-159 (Iran, Islamic Republic of); Faculty of Science, Zanjan University, Zanjan 313 (Iran, Islamic Republic of); Golestanian, Ramin [Institute for Advanced Studies in Basic Sciences, Zanjan 45195-159 (Iran, Islamic Republic of)

    2005-04-13

    We study the propulsion of two model swimmers at low Reynolds number. Inspired by Purcell's model, we propose a very simple one-dimensional swimmer consisting of three spheres that are connected by two arms whose lengths can change between two values. The proposed swimmer can swim with a special type of motion, which breaks the time-reversal symmetry. We also show that an ellipsoidal membrane with tangential travelling wave on it can also propel itself in the direction preferred by the travelling wave. This system resembles the realistic biological animals like Paramecium.

  8. Propulsion at low Reynolds number

    International Nuclear Information System (INIS)

    Najafi, Ali; Golestanian, Ramin

    2005-01-01

    We study the propulsion of two model swimmers at low Reynolds number. Inspired by Purcell's model, we propose a very simple one-dimensional swimmer consisting of three spheres that are connected by two arms whose lengths can change between two values. The proposed swimmer can swim with a special type of motion, which breaks the time-reversal symmetry. We also show that an ellipsoidal membrane with tangential travelling wave on it can also propel itself in the direction preferred by the travelling wave. This system resembles the realistic biological animals like Paramecium

  9. Number Theory, Analysis and Geometry

    CERN Document Server

    Goldfeld, Dorian; Jones, Peter

    2012-01-01

    Serge Lang was an iconic figure in mathematics, both for his own important work and for the indelible impact he left on the field of mathematics, on his students, and on his colleagues. Over the course of his career, Lang traversed a tremendous amount of mathematical ground. As he moved from subject to subject, he found analogies that led to important questions in such areas as number theory, arithmetic geometry, and the theory of negatively curved spaces. Lang's conjectures will keep many mathematicians occupied far into the future. In the spirit of Lang's vast contribution to mathematics, th

  10. A Precise Threshold for Quasi-Ramsey Numbers

    NARCIS (Netherlands)

    Kang, R.J.; Pach, J.; Patel, V.; Regts, G.

    2015-01-01

    We consider the variation of Ramsey numbers introduced by Erdös and Pach [J. Graph Theory, 7 (1983), pp. 137--147], where instead of seeking complete or independent sets we only seek a $t$-homogeneous set, a vertex subset that induces a subgraph of minimum degree at least $t$ or the complement of

  11. Number theory III Diophantine geometry

    CERN Document Server

    1991-01-01

    From the reviews of the first printing of this book, published as Volume 60 of the Encyclopaedia of Mathematical Sciences: "Between number theory and geometry there have been several stimulating influences, and this book records of these enterprises. This author, who has been at the centre of such research for many years, is one of the best guides a reader can hope for. The book is full of beautiful results, open questions, stimulating conjectures and suggestions where to look for future developments. This volume bears witness of the broad scope of knowledge of the author, and the influence of several people who have commented on the manuscript before publication ... Although in the series of number theory, this volume is on diophantine geometry, and the reader will notice that algebraic geometry is present in every chapter. ... The style of the book is clear. Ideas are well explained, and the author helps the reader to pass by several technicalities. Reading and rereading this book I noticed that the topics ...

  12. Banner prints social security numbers

    Directory of Open Access Journals (Sweden)

    Robbins RA

    2014-02-01

    Full Text Available No abstract available. Article truncated at 150 words. The Monday edition of the Arizona Republic contained a story with potential interest to our readers. On the most recent address labels of Banner Health's magazine, Smart & Healthy, the addressee's Social Security or Medicare identification numbers, which are often identical to their Social Security numbers (1. The magazine was mailed to more than 50,000 recipients in Arizona late last week. The recipients are members of the Medicare Pioneer Accountable Care Organization, a government health-care plan that Banner serves. Banner generated its mailing list from information it received from the U.S. Centers for Medicare & Medicaid Services, which is an agency within the U.S. Department of Health & Human Services (HHS responsible for administration of several federal health-care programs. Although medical information has been protected by the Health Insurance Portability and Accountability Act (HIPAA since 1996, penalties were recently increased. Civil monetary penalties were increased from a maximum of $100 ...

  13. Topics in Number Theory Conference

    CERN Document Server

    Andrews, George; Ono, Ken

    1999-01-01

    From July 31 through August 3,1997, the Pennsylvania State University hosted the Topics in Number Theory Conference. The conference was organized by Ken Ono and myself. By writing the preface, I am afforded the opportunity to express my gratitude to Ken for beng the inspiring and driving force behind the whole conference. Without his energy, enthusiasm and skill the entire event would never have occurred. We are extremely grateful to the sponsors of the conference: The National Sci­ ence Foundation, The Penn State Conference Center and the Penn State Depart­ ment of Mathematics. The object in this conference was to provide a variety of presentations giving a current picture of recent, significant work in number theory. There were eight plenary lectures: H. Darmon (McGill University), "Non-vanishing of L-functions and their derivatives modulo p. " A. Granville (University of Georgia), "Mean values of multiplicative functions. " C. Pomerance (University of Georgia), "Recent results in primality testing. " C. ...

  14. Cryptography and computational number theory

    CERN Document Server

    Shparlinski, Igor; Wang, Huaxiong; Xing, Chaoping; Workshop on Cryptography and Computational Number Theory, CCNT'99

    2001-01-01

    This volume contains the refereed proceedings of the Workshop on Cryptography and Computational Number Theory, CCNT'99, which has been held in Singapore during the week of November 22-26, 1999. The workshop was organized by the Centre for Systems Security of the Na­ tional University of Singapore. We gratefully acknowledge the financial support from the Singapore National Science and Technology Board under the grant num­ ber RP960668/M. The idea for this workshop grew out of the recognition of the recent, rapid development in various areas of cryptography and computational number the­ ory. The event followed the concept of the research programs at such well-known research institutions as the Newton Institute (UK), Oberwolfach and Dagstuhl (Germany), and Luminy (France). Accordingly, there were only invited lectures at the workshop with plenty of time for informal discussions. It was hoped and successfully achieved that the meeting would encourage and stimulate further research in information and computer s...

  15. Signals of lepton number violation

    CERN Document Server

    Panella, O; Srivastava, Y N

    1999-01-01

    The production of like-sign-dileptons (LSD), in the high energy lepton number violating ( Delta L=+2) reaction, pp to 2jets+l/sup +/l /sup +/, (l=e, mu , tau ), of interest for the experiments to be performed at the forthcoming Large Hadron Collider (LHC), is reported, taking up a composite model scenario in which the exchanged virtual composite neutrino is assumed to be a Majorana particle. Numerical estimates of the corresponding signal cross-section that implement kinematical cuts needed to suppress the standard model background, are presented which show that in some regions of the parameter space the total number of LSD events is well above the background. Assuming non-observation of the LSD signal it is found that LHC would exclude a composite Majorana neutrino up to 700 GeV (if one requires 10 events for discovery). The sensitivity of LHC experiments to the parameter space is then compared to that of the next generation of neutrinoless double beta decay ( beta beta /sub 0 nu /) experiment, GENIUS, and i...

  16. Induced Abortion

    Science.gov (United States)

    ... Search FAQs Induced Abortion Page Navigation ▼ ACOG Pregnancy Book Induced Abortion Patient Education FAQs Induced Abortion Patient ... given for the procedure? Before the procedure, local anesthesia is given to numb the cervix. Sedatives may ...

  17. Polynomials formalism of quantum numbers

    International Nuclear Information System (INIS)

    Kazakov, K.V.

    2005-01-01

    Theoretical aspects of the recently suggested perturbation formalism based on the method of quantum number polynomials are considered in the context of the general anharmonicity problem. Using a biatomic molecule by way of example, it is demonstrated how the theory can be extrapolated to the case of vibrational-rotational interactions. As a result, an exact expression for the first coefficient of the Herman-Wallis factor is derived. In addition, the basic notions of the formalism are phenomenologically generalized and expanded to the problem of spin interaction. The concept of magneto-optical anharmonicity is introduced. As a consequence, an exact analogy is drawn with the well-known electro-optical theory of molecules, and a nonlinear dependence of the magnetic dipole moment of the system on the spin and wave variables is established [ru

  18. Galaxy number counts: Pt. 2

    International Nuclear Information System (INIS)

    Metcalfe, N.; Shanks, T.; Fong, R.; Jones, L.R.

    1991-01-01

    Using the Prime Focus CCD Camera at the Isaac Newton Telescope we have determined the form of the B and R galaxy number-magnitude count relations in 12 independent fields for 21 m ccd m and 19 m ccd m 5. The average galaxy count relations lie in the middle of the wide range previously encompassed by photographic data. The field-to-field variation of the counts is small enough to define the faint (B m 5) galaxy count to ±10 per cent and this variation is consistent with that expected from galaxy clustering considerations. Our new data confirm that the B, and also the R, galaxy counts show evidence for strong galaxy luminosity evolution, and that the majority of the evolving galaxies are of moderately blue colour. (author)

  19. Put numbers on the sustainability

    DEFF Research Database (Denmark)

    Hauschild, Michael Zwicky

    2014-01-01

    life cycle Environmental sustainability encompasses multiple types of environmental impact ranging from the global scale like climate change and stratospheric ozone depletion over regional impacts associated with air pollution impacts causing acidification, photochemical ozone formation and particle...... exposure of humans, to the local impacts associated with physical transformation of land and extraction of water. Chemicals can cause toxic impacts to humans and ecosystems on all scales. All these impacts need to be quantified if we want to put numbers on sustainability. The life cycle perspective......Sustainability is about meeting the needs of the present without compromising the possibilities for our future generations to meet their needs and is commonly perceived as comprising three dimensions – a social, an economic and an environmental dimension, e.g. in the triple bottom line thinking...

  20. Fermionic relatives of Stirling and Lah numbers

    International Nuclear Information System (INIS)

    Schork, Matthias

    2003-01-01

    In this paper certain 'fermionic' Stirling numbers introduced recently are discussed. Roughly speaking, these numbers are obtained by taking the 'fermionic' limit q →-1 of the q-deformed Stirling numbers. The usual Stirling numbers correspond in this language to the 'bosonic' limit q → 1. It is shown that the fermionic Stirling numbers are given by binomial coefficients and that they satisfy the same relations as the undeformed Stirling numbers. The fermionic relatives of Lah numbers are also very briefly discussed

  1. Natural convection inside an irregular porous cavity; Conveccao natural no interior de uma cavidade porosa irregular

    Energy Technology Data Exchange (ETDEWEB)

    Beltran, Jorge I. LLagostera; Trevisan, Osvair Vidal [Universidade Estadual de Campinas, SP (Brazil). Faculdade de Engenharia Mecanica. Dept. de Energia

    1990-12-31

    Natural convection flow induced by heating from below in a irregular porous cavity is investigated numerically. The influence of the modified Rayleigh number and geometric ratios on heat transfer and fluid flow is studied. Global and local Nusselt for Rayleigh numbers covering the range 0 - 1600 and for several geometric ratios. The fluid flow and the temperature field are illustrated by contour maps. (author) 6 refs., 10 figs., 7 tabs.

  2. Inducing Lactation: Breastfeeding for Adoptive Moms

    Science.gov (United States)

    ... Español Text Size Email Print Share Inducing Lactation: Breastfeeding for Adoptive Moms Page Content Article Body A growing number of adoptive mothers are interested in breastfeeding their babies through induced lactation. Prescription Medications No ...

  3. Some further results on Legendre numbers

    Directory of Open Access Journals (Sweden)

    Paul W. Haggard

    1988-01-01

    Full Text Available The Legendre numbers, Pnm, are expressed in terms of those numbers, Pkm−1, in the previous column down to Pnm and in terms of those, Pkm, above but in the same column. Other results are given for numbers close to a given number. The limit of the quotient of two consecutive non-zero numbers in any one column is shown to be −1. Bounds for the Legendre numbers are described by circles centered at the origin. A connection between Legendre numbers and Pascal numbers is exhibited by expressing the Legendre numbers in terms of combinations.

  4. Effect of particle shape and slip mechanism on buoyancy induced convective heat transport with nanofluids

    Science.gov (United States)

    Joshi, Pranit Satish; Mahapatra, Pallab Sinha; Pattamatta, Arvind

    2017-12-01

    Experiments and numerical simulation of natural convection heat transfer with nanosuspensions are presented in this work. The investigations are carried out for three different types of nanosuspensions: namely, spherical-based (alumina/water), tubular-based (multi-walled carbon nanotube/water), and flake-based (graphene/water). A comparison with in-house experiments is made for all the three nanosuspensions at different volume fractions and for the Rayleigh numbers in the range of 7 × 105-1 × 107. Different models such as single component homogeneous, single component non-homogeneous, and multicomponent non-homogeneous are used in the present study. From the present numerical investigation, it is observed that for lower volume fractions (˜0.1%) of nanosuspensions considered, single component models are in close agreement with the experimental results. Single component models which are based on the effective properties of the nanosuspensions alone can predict heat transfer characteristics very well within the experimental uncertainty. Whereas for higher volume fractions (˜0.5%), the multi-component model predicts closer results to the experimental observation as it incorporates drag-based slip force which becomes prominent. The enhancement observed at lower volume fractions for non-spherical particles is attributed to the percolation chain formation, which perturbs the boundary layer and thereby increases the local Nusselt number values.

  5. Buoyancy Induced Heat Transfer and Fluid Flow Inside a Prismatic Cavity

    International Nuclear Information System (INIS)

    Aich, Walid; Omri, Ahmed; Ben Nasrallah, Sassi

    2009-01-01

    This paper deals with a numerical simulation of natural convection flows in a prismatic cavity. This configuration represents solar energy collectors, conventional attic spaces of greenhouses and buildings with pitched roofs. The third dimension of the cavity is considered long enough for the flow to be considered 2D. The base is submitted to a uniform heat flux, the two top inclined walls are symmetrically cooled and the two vertical walls are assumed to be perfect thermal insulators. The aim of the study is to examine the thermal exchange by natural convection and effects of buoyancy forces on flow structure. The study provides useful information on the flow structure sensitivity to the governing parameters, the Rayleigh number (Ra) and the aspect ratio of the cavity. The hydrodynamic and thermal fields, the local Nusselt number, the temperature profile at the bottom and at the center of the cavity are investigated for a large range of Ra. The effect of the aspect ratio is examined for different values of Ra. Based on the authors knowledge, no previous results on natural convection in this geometry exist

  6. IEEE Standard for Floating Point Numbers

    Indian Academy of Sciences (India)

    IAS Admin

    is to decide how to represent real numbers using these bits. Normally, in ... numbers explained above, the largest floating point number which can be represented is. The number of bits to be used for the mantissa is determined by the number of significant decimal .... This is used to give an error message. When an operation.

  7. The magic of a number system

    DEFF Research Database (Denmark)

    Elmasry, Amr Ahmed Abd Elmoneim; Jensen, Claus; Katajainen, Jyrki

    2010-01-01

    We introduce a new number system that supports increments with a constant number of digit changes. We also give a simple method that extends any number system supporting increments to support decrements using the same number of digit changes. In the new number system the weight of the ith digit i...

  8. ON THE BINARY DIGITS OF ALGEBRAIC NUMBERS

    OpenAIRE

    KANEKO, HAJIME

    2010-01-01

    Borel conjectured that all algebraic irrational numbers are normal in base 2. However, very little is known about this problem. We improve the lower bounds for the number of digit changes in the binary expansions of algebraic irrational numbers.

  9. Essays on the theory of numbers

    CERN Document Server

    Dedekind, Richard

    1963-01-01

    Two classic essays by great German mathematician: one provides an arithmetic, rigorous foundation for the irrational numbers, the other is an attempt to give the logical basis for transfinite numbers and properties of the natural numbers.

  10. What Do Numbers Do in Transnational Governance?

    DEFF Research Database (Denmark)

    Krause Hansen, Hans; Porter, Tony

    2012-01-01

    This study examines how numbers in transnational governance constitute actors, objects, and relationships, including relationships of power. We review the existing literatures on numbers for insights relevant to their role in transnational governance, including the ontology of numbers, the histor...

  11. How to be Brilliant at Numbers

    CERN Document Server

    Webber, Beryl

    2010-01-01

    How to be Brilliant at Numbers will help students to develop an understanding of numbers, place value, fractions and decimals. They will develop the language of number, and of the relationships between numbers. They will also use mathematics to solve problems and will develop mathematical reasoning. Using the worksheets in this book, pupils will learn about: ancient Greek numbers; coins; digits; consecutive numbers; magic ladders; fractions; matching pairs; multiples of 10; rounding; decimal un

  12. Number sense in teaching and learning arithmetic

    DEFF Research Database (Denmark)

    Rezat, Sebastian; Ejersbo, Lisser Rye

    2018-01-01

    From the beginning of CERME conferences, the concept of number sense and its relation to the teaching and learning arithmetic and number systems has been a central theme. However, different meanings of the term have been used, and it has not always been clear which meaning is referred to. Depending......? Second, what can be done to foster the development of number sense? Third, what is the scope of number sense in terms of different number domains including fractions and negative numbers?...

  13. Hyperthermia-induced apoptosis

    NARCIS (Netherlands)

    Nijhuis, E.H.A.

    2008-01-01

    This thesis describes a number of studies that investigated several aspects of heat-induced apoptosis in human lymphoid malignancies. Cells harbour both pro- and anti-apoptotic proteins and the balance between these proteins determines whether a cell is susceptible to undergo apoptosis. In this

  14. 7 CFR 987.102 - Lot number.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Lot number. 987.102 Section 987.102 Agriculture... RIVERSIDE COUNTY, CALIFORNIA Administrative Rules Definitions § 987.102 Lot number. Lot number is synonymous... letters or numbers, or both, imprinted on the containers shall differ from those of any other lot coded...

  15. Visuospatial Priming of the Mental Number Line

    Science.gov (United States)

    Stoianov, Ivilin; Kramer, Peter; Umilta, Carlo; Zorzi, Marco

    2008-01-01

    It has been argued that numbers are spatially organized along a "mental number line" that facilitates left-hand responses to small numbers, and right-hand responses to large numbers. We hypothesized that whenever the representations of visual and numerical space are concurrently activated, interactions can occur between them, before response…

  16. The Decimal Number System and Young Children

    Science.gov (United States)

    Harrison, John

    2006-01-01

    In this article, the author believes that a visual image of the number system is helpful to everyone, especially children, in understanding what is, after all, an abstract idea. The simplest model is the number line, a row of equally spaced numbers, starting at zero. This illustrates the continuous progression of the natural numbers, moving to the…

  17. Stirling numbers and integer partitions | Merca | Quaestiones ...

    African Journals Online (AJOL)

    In this paper, we prove that the Stirling numbers of both kinds can be written as sums over integer partitions. As corollaries, we rewrite some identities with Stirling numbers of both kinds without Stirling numbers. Keywords: Integer partitions, symmetric functions, Stirling numbers ...

  18. Question of the total gene number in Drosophila melanogaster

    International Nuclear Information System (INIS)

    Lefevre, G.; Watkins, W.

    1986-01-01

    A statistical analysis has been carried out on the distribution and allelism of nearly 500 sex-linked, X-ray-induced, cytologically normal and rearranged lethal mutations in Drosophila melanogaster that were obtained by G. Lefevre. The mutations were induced in four different regions of the X chromosome: (1) 1A1-3E8, (2) 6D1-8A5, (3) 9E1-11A7 and (4) 19A1-20F4, which together comprise more than one-third of the entire chromosome.--The analysis shows that the number of alleles found at different loci does not fit a Poisson distribution, even when the proper procedures are taken to accommodate the truncated nature of the data. However, the allele distribution fits a truncated negative binomial distribution quite well, with cytologically normal mutations fitting better than rearrangement mutations. This indicates that genes are not equimutable, as required for the data to fit a Poisson distribution.--Using the negative binomial parameters to estimate the number of genes that did not produce a detectable lethal mutation in our experiment (n0) gave a larger number than that derived from the use of the Poisson parameter. Unfortunately, we cannot estimate the total numbers of nonvital loci, loci with undetectable phenotypes and loci having extremely low mutabilities. In any event, our estimate of the total vital gene number was far short of the total number of bands in the analyzed regions; yet, in several short intervals, we have found more vital genes than bands; in other intervals, fewer. We conclude that the one-band, one-gene hypothesis, in its literal sense, is not true; furthermore, it is difficult to support, even approximately.--The question of the total gene number in Drosophila will, not doubt, eventually be solved by molecular analyses, not by statistical analysis of mutation data or saturation studies

  19. [Exercise induced hyponatremia].

    Science.gov (United States)

    Hadad, Eran; Rosen, Eli; Heled, Yuval; Moran, Daniel S; Schindel, Yair

    2004-05-01

    A normal water-electrolyte balance is essential for normal function of body systems during physical activity. During recent years, awareness of the importance of drinking amongst athletes and Israeli Defense Force (IDF) soldiers, in particular, has been highlighted. A large number of athletes tend to drink prior to, during and after their exercise in order to enhance physical abilities and to prevent heat casualties and dehydration. However, excessive water consumption combined with sweat induced electrolytes loss during physical activity, may cause hyponatremia in extreme cases. Recently, several cases of exercise induced hyponatremia were reported in the IDF, resulting from improper water consumption. In this article, we describe a clinical case of exercise-induced hyponatremia in a soldier and a review of the literature, including the etiology, clinical characterization and recommended treatment. Moreover, water consumption recommendations with regard to physical activity are presented. The application of such recommendations may prevent future events of exercise-induced hyponatremia.

  20. On domination multisubdivision number of unicyclic graphs

    Directory of Open Access Journals (Sweden)

    Joanna Raczek

    2018-01-01

    Full Text Available The paper continues the interesting study of the domination subdivision number and the domination multisubdivision number. On the basis of the constructive characterization of the trees with the domination subdivision number equal to 3 given in [H. Aram, S.M. Sheikholeslami, O. Favaron, Domination subdivision number of trees, Discrete Math. 309 (2009, 622-628], we constructively characterize all connected unicyclic graphs with the domination multisubdivision number equal to 3. We end with further questions and open problems.

  1. Deafness for the meanings of number words

    OpenAIRE

    Caño, Agnès; Rapp, Brenda; Costa, Albert; Juncadella, Montserrat

    2007-01-01

    We describe the performance of an aphasic individual who showed a selective impairment affecting his comprehension of auditorily presented number words and not other word categories. His difficulty in number word comprehension was restricted to the auditory modality, given that with visual stimuli (written words, Arabic numerals and pictures) his comprehension of number and non-number words was intact. While there have been previous reports of selective difficulty or sparing of number words a...

  2. Fast integration using quasi-random numbers

    International Nuclear Information System (INIS)

    Bossert, J.; Feindt, M.; Kerzel, U.

    2006-01-01

    Quasi-random numbers are specially constructed series of numbers optimised to evenly sample a given s-dimensional volume. Using quasi-random numbers in numerical integration converges faster with a higher accuracy compared to the case of pseudo-random numbers. The basic properties of quasi-random numbers are introduced, various generators are discussed and the achieved gain is illustrated by examples

  3. Fast integration using quasi-random numbers

    Science.gov (United States)

    Bossert, J.; Feindt, M.; Kerzel, U.

    2006-04-01

    Quasi-random numbers are specially constructed series of numbers optimised to evenly sample a given s-dimensional volume. Using quasi-random numbers in numerical integration converges faster with a higher accuracy compared to the case of pseudo-random numbers. The basic properties of quasi-random numbers are introduced, various generators are discussed and the achieved gain is illustrated by examples.

  4. Radiation Induced Vaccination to Breast Cancer

    Science.gov (United States)

    2016-12-01

    Award Number: W81XWH-11-1-0531 TITLE: Radiation-Induced Vaccination to Breast Cancer PRINCIPAL INVESTIGATOR: William H. McBride CONTRACTING...TITLE AND SUBTITLE Radiation-Induced Vaccination to Breast Cancer 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-11-1-0531 5c. PROGRAM ELEMENT NUMBER 6...therapy to generate an in situ tumor vaccine and abscopal effects at distant tumor sites (13), giving some rationale for this attempt to examine this

  5. DNS of heat transfer in turbulent and transitional channel flow obstructed by rectangular prisms

    Energy Technology Data Exchange (ETDEWEB)

    Kawamura, Fusao; Seki, Yohji; Iwamoto, Kaoru [Department of Mechanical Engineering, Tokyo University of Science, Noda-shi, Chiba 278-8510 (Japan); Kawamura, Hiroshi [Department of Mechanical Engineering, Tokyo University of Science, Noda-shi, Chiba 278-8510 (Japan)], E-mail: kawa@rs.noda.tus.ac.jp

    2007-12-15

    Direct numerical simulation (DNS) of heat transfer in a channel flow obstructed by rectangular prisms has been performed for Re{sub {tau}} = 80-20, where Re{sub {tau}} is based on the friction velocity, the channel half width and the kinematic viscosity. The molecular Prandtl number is set to be 0.71. The flow remains unsteady down to Re{sub {tau}} = 40 owing to the disturbance induced by the prism. For Re{sub {tau}} = 30 and 20, the flow results in a steady laminar flow. In the vicinity of the prism, the three-dimensional complex vortices are generated and heat transfer is enhanced. The Reynolds number effect on the time-averaged vortex structure and the local Nusselt number are investigated. The mechanism of the heat transfer enhancement is discussed. In addition, the mean flow parameters such as the friction factor and the Nusselt number are examined in comparison with existing DNS and experimental data.

  6. Group Sunspot Numbers: Sunspot Cycle Characteristics

    Science.gov (United States)

    Hathaway, D. H.; Wilson, R. M.; Reichmann, E. J.; Six, N. Frank (Technical Monitor)

    2002-01-01

    We examine the "Group" sunspot numbers constructed by Hoyt and Schatten to determine their utility in characterizing the solar activity cycle. We compare smoothed monthly Group Sunspot Numbers to Zurich (International) Sunspot Numbers, 10.7-cm radio flux, and total sunspot area. We find that the Zurich numbers follow the 10.7-cm radio flux and total sunspot area measurements slightly better than the Group numbers. We examine several significant characteristics of the sunspot cycle using both Group numbers and Zurich numbers. We find that the "Waldmeier Effect" - the anti-correlation between cycle amplitude and the elapsed time between minimum and maximum of a cycle - is much more apparent in the Zurich numbers. The "Amplitude-Period Effect" the anti-correlation between cycle amplitude and the length of the previous cycle from minimum to minimum - is also much more apparent in the Zurich numbers. The "Amplitude-Minimum Effect" - the correlation between cycle amplitude and the activity level at the previous (onset) minimum is equally apparent in both the Zurich numbers and the Group numbers. The "Even-Odd Effect" - in which odd-numbered cycles are larger than their even-numbered precursors - is somewhat stronger in the Group numbers but with a tighter relationship in the Zurich numbers. The "Secular Trend" - the increase in cycle amplitudes since the Maunder Minimum - is much stronger in Group numbers. After removing this trend we find little evidence for multi-cycle periodicities like the 80 year Gleissberg cycle or the two- and three-cycle periodicities. We also find little evidence for a correlation between the amplitude of a cycle and its period or for a bimodal distribution of cycle periods. We conclude that the Group numbers are most useful for extending the sunspot cycle data further back in time and thereby adding more cycles and improving the statistics. However, the Zurich numbers are more useful for characterizing the on-going levels of solar activity.

  7. The Translated Dowling Polynomials and Numbers.

    Science.gov (United States)

    Mangontarum, Mahid M; Macodi-Ringia, Amila P; Abdulcarim, Normalah S

    2014-01-01

    More properties for the translated Whitney numbers of the second kind such as horizontal generating function, explicit formula, and exponential generating function are proposed. Using the translated Whitney numbers of the second kind, we will define the translated Dowling polynomials and numbers. Basic properties such as exponential generating functions and explicit formula for the translated Dowling polynomials and numbers are obtained. Convexity, integral representation, and other interesting identities are also investigated and presented. We show that the properties obtained are generalizations of some of the known results involving the classical Bell polynomials and numbers. Lastly, we established the Hankel transform of the translated Dowling numbers.

  8. Observing Optional Number in DDC Edition 23

    Directory of Open Access Journals (Sweden)

    Rotmianto Mohamad

    2018-01-01

    Full Text Available Dewey Decimal Classification is a most popular classification system in the world because of its completeness and most up-to-date. There are many optional number in this classification system, although it rarely to be discussed even it is important to known well about that optional number, especially for a librarian as classifier. This paper is a literature study about Dewey Decimal Classification Edition 23, to describe about optional numbers, particularly the number in relationship with Indonesia’s subject and discipline. This paper is to avoid misunderstanding in interpreted about optional number among librarians, especially for who that does not understand well about optional numbers.

  9. Power sum identities with generalized Stirling numbers

    OpenAIRE

    Boyadzhiev, Khristo N.

    2009-01-01

    Several combinatorial identities are presented, involving Stirling functions of the second kind with a complex variable. The identities involve also Stirling numbers of the first kind, binomial coefficients and harmonic numbers.

  10. Number Systems. Popular Lectures in Mathematics.

    Science.gov (United States)

    Fomin, S. V.

    The origin, properties, and applications of various number systems are discussed. Among the 15 topics discussed are: tests for divisibility, the binary system, the game of Nim, computers, and infinite number representations. (MK)

  11. Caspar Wessel on representing complex numbers (1799)

    DEFF Research Database (Denmark)

    Branner, Bodil

    1999-01-01

    In celebration of the bicentenary of the publication of Wessel's paper on the geometric interpretation of complex numbers it is decsribed how Wessel used complex numbers to represent directions in surveying, at least as early as 1787.......In celebration of the bicentenary of the publication of Wessel's paper on the geometric interpretation of complex numbers it is decsribed how Wessel used complex numbers to represent directions in surveying, at least as early as 1787....

  12. Relativistic theory of tidal Love numbers

    OpenAIRE

    Binnington, Taylor; Poisson, Eric

    2009-01-01

    In Newtonian gravitational theory, a tidal Love number relates the mass multipole moment created by tidal forces on a spherical body to the applied tidal field. The Love number is dimensionless, and it encodes information about the body's internal structure. We present a relativistic theory of Love numbers, which applies to compact bodies with strong internal gravities; the theory extends and completes a recent work by Flanagan and Hinderer, which revealed that the tidal Love number of a neut...

  13. Evaluating Number Sense in Workforce Students

    Science.gov (United States)

    Steinke, Dorothea A.

    2015-01-01

    Earlier institution-sponsored research revealed that about 20% of students in community college basic math and pre-algebra programs lacked a sense of part-whole relationships with whole numbers. Using the same tool with a group of 86 workforce students, about 75% placed five whole numbers on an empty number line in a way that indicated lack of…

  14. On double Hurwitz numbers with completed cycles

    NARCIS (Netherlands)

    Shadrin, S.; Spitz, L.; Zvonkine, D.

    2012-01-01

    In this paper, we collect a number of facts about double Hurwitz numbers, where the simple branch points are replaced by their more general analogues: completed (r + 1)-cycles. In particular, we give a geometric interpretation of these generalized Hurwitz numbers and derive a cut-and-join operator

  15. On the interpretation of number and classifiers

    NARCIS (Netherlands)

    Cheng, L.L.; Doetjes, J.S.; Sybesma, R.P.E.; Zamparelli, R.

    2012-01-01

    Mandarin and Cantonese, both of which are numeral classifier languages, present an interesting puzzle concerning a compositional account of number in the various forms of nominals. First, bare nouns are number neutral (or vague in number). Second, cl-noun combinations appear to have different

  16. Graphing Powers and Roots of Complex Numbers.

    Science.gov (United States)

    Embse, Charles Vonder

    1993-01-01

    Using De Moivre's theorem and a parametric graphing utility, examines powers and roots of complex numbers and allows students to establish connections between the visual and numerical representations of complex numbers. Provides a program to numerically verify the roots of complex numbers. (MDH)

  17. 48 CFR 304.7001 - Numbering acquisitions.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Numbering acquisitions. 304.7001 Section 304.7001 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATIVE MATTERS Acquisition Instrument Identification Numbering System 304.7001 Numbering acquisitions. (a...

  18. Developmental Changes in the Whole Number Bias

    Science.gov (United States)

    Braithwaite, David W.; Siegler, Robert S.

    2018-01-01

    Many students' knowledge of fractions is adversely affected by whole number bias, the tendency to focus on the separate whole number components (numerator and denominator) of a fraction rather than on the fraction's magnitude (ratio of numerator to denominator). Although whole number bias appears early in the fraction learning process and under…

  19. 7 CFR 29.32 - Identification number.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Identification number. 29.32 Section 29.32 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... INSPECTION Regulations Definitions § 29.32 Identification number. A number or a combination of letters and...

  20. An Introduction to Conway's Games and Numbers

    OpenAIRE

    Schleicher, Dierk; Stoll, Michael

    2004-01-01

    This is an introduction into John Conway's beautiful Combinatorial Game Theory, providing precise statements and detailed proofs for the fundamental parts of his theory. (1) Combinatorial game theory, (2) the GROUP of games, (3) the FIELD of numbers, (4) ordinal numbers, (5) games and numbers, (6) infinitesimal games, (7) impartial games.

  1. The development of the number field sieve

    CERN Document Server

    Lenstra, Hendrik

    1993-01-01

    The number field sieve is an algorithm for finding the prime factors of large integers. It depends on algebraic number theory. Proposed by John Pollard in 1988, the method was used in 1990 to factor the ninth Fermat number, a 155-digit integer. The algorithm is most suited to numbers of a special form, but there is a promising variant that applies in general. This volume contains six research papers that describe the operation of the number field sieve, from both theoretical and practical perspectives. Pollard's original manuscript is included. In addition, there is an annotated bibliography of directly related literature.

  2. Fibonacci and Catalan Numbers An Introduction

    CERN Document Server

    Grimaldi, Ralph

    2012-01-01

    In this one-of-a-kind book, Ralph Grimaldi uses his extensive experience from the classroom and as a leader of mini-courses to present an accessible, single resource on the topics of Fibonacci Numbers and Catalan Numbers . The book first embarks on a complete treatment of Fibonacci numbers. Starting with a historical background on the topic, the author goes on to present the properties of Fibonacci numbers, a slew of introductory-level examples, and in-depth discussion of related topics including compositions and palindromes; tiling and Fibonacci numbers

  3. An adventurer's guide to number theory

    CERN Document Server

    Friedberg, Richard

    1995-01-01

    In this delightful guide, a noted mathematician and teacher offers a witty, historically oriented introduction to number theory, dealing with properties of numbers and with numbers as abstract concepts. Written for readers with an understanding of arithmetic and beginning algebra, the book presents the classical discoveries of number theory, including the work of Pythagoras, Euclid, Diophantus, Fermat, Euler, Lagrange and Gauss.Unlike many authors, however, Mr. Friedberg encourages students to think about the imaginative, playful qualities of numbers as they consider such subjects as primes

  4. Approximation of complex algebraic numbers by algebraic numbers of bounded degree

    OpenAIRE

    Bugeaud, Yann; Evertse, Jan-Hendrik

    2007-01-01

    We investigate how well complex algebraic numbers can be approximated by algebraic numbers of degree at most n. We also investigate how well complex algebraic numbers can be approximated by algebraic integers of degree at most n+1. It follows from our investigations that for every positive integer n there are complex algebraic numbers of degree larger than n that are better approximable by algebraic numbers of degree at most n than almost all complex numbers. As it turns out, these numbers ar...

  5. Fibonacci number of the tadpole graph

    Directory of Open Access Journals (Sweden)

    Joe DeMaio

    2014-10-01

    Full Text Available In 1982, Prodinger and Tichy defined the Fibonacci number of a graph G to be the number of independent sets of the graph G. They did so since the Fibonacci number of the path graph Pn is the Fibonacci number F(n+2 and the Fibonacci number of the cycle graph Cn is the Lucas number Ln. The tadpole graph Tn,k is the graph created by concatenating Cn and Pk with an edge from any vertex of Cn to a pendant of Pk for integers n=3 and k=0. This paper establishes formulae and identities for the Fibonacci number of the tadpole graph via algebraic and combinatorial methods.

  6. Neocortical glial cell numbers in human brains

    DEFF Research Database (Denmark)

    Pelvig, D.P.; Pakkenberg, H.; Stark, A.K.

    2008-01-01

    and neurons and counting were done in each of the four lobes. The study showed that the different subpopulations of glial cells behave differently as a function of age; the number of oligodendrocytes showed a significant 27% decrease over adult life and a strong correlation to the total number of neurons...... while the total astrocyte number is constant through life; finally males have a 28% higher number of neocortical glial cells and a 19% higher neocortical neuron number than females. The overall total number of neocortical neurons and glial cells was 49.3 billion in females and 65.2 billion in males......, a difference of 24% with a high biological variance. These numbers can serve as reference values in quantitative studies of the human neocortex. (C) 2007 Elsevier Inc. All rights reserved Udgivelsesdato: 2008/11...

  7. Glucocorticoids decrease Treg cell numbers in lungs of allergic mice.

    Science.gov (United States)

    Olsen, P C; Kitoko, J Z; Ferreira, T P; de-Azevedo, C T; Arantes, A C; Martins, Μ A

    2015-01-15

    Glucocorticoids have been the hallmark anti-inflammatory drug used to treat asthma. It has been shown that glucocorticoids ameliorate asthma by increasing numbers and activity of Tregs, in contrast recent data show that glucocorticoid might have an opposite effect on Treg cells from normal mice. Since Tregs are target cells that act on the resolution of asthma, the aim of this study was to elucidate the effect of glucocorticoid treatment on lung Tregs in mouse models of asthma. Allergen challenged mice were treated with either oral dexamethasone or nebulized budesonide. Broncoalveolar lavage and airway hyperresponsiveness were evaluated after allergenic challenge. Lung, thymic and lymph node cells were phenotyped on Treg through flow cytometry. Lung cytokine secretion was detected by ELISA. Although dexamethasone inhibited airway inflammation and hyperresponsiveness, improving resolution, we have found that both dexamethasone and budesonide induce a reduction of Treg numbers on lungs and lymphoid organs of allergen challenged mice. The reduction of lung Treg levels was independent of mice strain or type of allergen challenge. Our study also indicates that both glucocorticoids do not increase Treg activity through production of IL-10. Glucocorticoid systemic or localized treatment induced thymic atrophy. Taken together, our results demonstrate that glucocorticoids decrease Treg numbers and activity in different asthma mouse models, probably by reducing thymic production of T cells. Therefore, it is possible that glucocorticoids do not have beneficial effects on lung populations of Treg cells from asthmatic patients. Copyright © 2014 Elsevier B.V. All rights reserved.

  8. An Evaluation of App-Based and Paper-Based Number Lines for Teaching Number Comparison

    Science.gov (United States)

    Weng, Pei-Lin; Bouck, Emily C.

    2016-01-01

    Number comparison is a fundamental skill required for academic and functional mathematics (e.g., time, money, purchasing) for students with disabilities. The most commonly used method to teach number comparison is number lines. Although historically paper number lines are used, app-based number lines may offer greater flexibility. This study…

  9. Mixing of two miscible fluids at high Schmidt number

    Science.gov (United States)

    Simmons, Mark; Alberini, Federico; Pain, Christopher; Matar, Omar

    2013-11-01

    The blending of two miscible liquids at high Schmidt number is an increasingly common industrial problem: as processes push towards shorter timescales yet the rheology of the fluids becomes increasingly complex. This leads to phenomena which resemble a quasi two-phase system with zero interfacial tension. In this study, we compare experimental results with computational fluid dynamics simulations using unstructured-mesh adaptivity for the flow of two Newtonian, or two power-law fluids through a complex geometry representative of a Kenics type static mixer used in industry. The geometry induces a stretching and folding of the fluid elements which causes exponential growth of the interface length down the geometry. The interfacial topology obtained from the simulations is compared with experiments carried out using Planar Laser Induced Fluorescence (PLIF), which enables the spatial distribution of each phase, and the interfaces between them, to be determined at the outlet of the geometry. EPSRC Programme Grant EP/K003976/1.

  10. Object-based neglect in number processing

    Science.gov (United States)

    2013-01-01

    Recent evidence suggests that neglect patients seem to have particular problems representing relatively smaller numbers corresponding to the left part of the mental number line. However, while this indicates space-based neglect for representational number space little is known about whether and - if so - how object-based neglect influences number processing. To evaluate influences of object-based neglect in numerical cognition, a group of neglect patients and two control groups had to compare two-digit numbers to an internally represented standard. Conceptualizing two-digit numbers as objects of which the left part (i.e., the tens digit should be specifically neglected) we were able to evaluate object-based neglect for number magnitude processing. Object-based neglect was indicated by a larger unit-decade compatibility effect actually reflecting impaired processing of the leftward tens digits. Additionally, faster processing of within- as compared to between-decade items provided further evidence suggesting particular difficulties in integrating tens and units into the place-value structure of the Arabic number system. In summary, the present study indicates that, in addition to the spatial representation of number magnitude, also the processing of place-value information of multi-digit numbers seems specifically impaired in neglect patients. PMID:23343126

  11. On the binary expansions of algebraic numbers

    Energy Technology Data Exchange (ETDEWEB)

    Bailey, David H.; Borwein, Jonathan M.; Crandall, Richard E.; Pomerance, Carl

    2003-07-01

    Employing concepts from additive number theory, together with results on binary evaluations and partial series, we establish bounds on the density of 1's in the binary expansions of real algebraic numbers. A central result is that if a real y has algebraic degree D > 1, then the number {number_sign}(|y|, N) of 1-bits in the expansion of |y| through bit position N satisfies {number_sign}(|y|, N) > CN{sup 1/D} for a positive number C (depending on y) and sufficiently large N. This in itself establishes the transcendency of a class of reals {summation}{sub n{ge}0} 1/2{sup f(n)} where the integer-valued function f grows sufficiently fast; say, faster than any fixed power of n. By these methods we re-establish the transcendency of the Kempner--Mahler number {summation}{sub n{ge}0}1/2{sup 2{sup n}}, yet we can also handle numbers with a substantially denser occurrence of 1's. Though the number z = {summation}{sub n{ge}0}1/2{sup n{sup 2}} has too high a 1's density for application of our central result, we are able to invoke some rather intricate number-theoretical analysis and extended computations to reveal aspects of the binary structure of z{sup 2}.

  12. Cortical areas involved in Arabic number reading.

    Science.gov (United States)

    Roux, F-E; Lubrano, V; Lauwers-Cances, V; Giussani, C; Démonet, J-F

    2008-01-15

    Distinct functional pathways for processing words and numbers have been hypothesized from the observation of dissociated impairments of these categories in brain-damaged patients. We aimed to identify the cortical areas involved in Arabic number reading process in patients operated on for various brain lesions. Direct cortical electrostimulation was prospectively used in 60 brain mappings. We used object naming and two reading tasks: alphabetic script (sentences and number words) and Arabic number reading. Cortical areas involved in Arabic number reading were identified according to location, type of interference, and distinctness from areas associated with other language tasks. Arabic number reading was sustained by small cortical areas, often extremely well localized (area (Brodmann area 45), the anterior part of the dominant supramarginal gyrus (Brodmann area 40; p area (Brodmann area 37; p areas.

  13. CT number of the fatty liver

    International Nuclear Information System (INIS)

    Maeda, Hiroko; Kawai, Takeshi; Kanasaki, Yoshiki; Akagi, Hiroaki

    1981-01-01

    This report is studied on CT number and CT images of the eight cases with fatty liver. Five of these cases showed the reversal of densities of the liver and vessels. In these cases, the diagnoses of the fatty liver were easible. In other cases, the diagnoses were possible only by comparison of the CT number of the liver and spleen because the CT number of normal liver were higher than those of the spleen. In the results which we examined the correlation of the CT number and specific gravities of the blood, normal saline, distilled water, mayonnaise, eatable iol, ethyl alcohol and lard, we observed the linear relationship between CT number and specific gravities. And so, we think that the diagnosis of the fatty liver and the degree of fatty infiltration can be guessed by the CT number of the liver and spleen. (author)

  14. Relativistic theory of tidal Love numbers

    International Nuclear Information System (INIS)

    Binnington, Taylor; Poisson, Eric

    2009-01-01

    In Newtonian gravitational theory, a tidal Love number relates the mass multipole moment created by tidal forces on a spherical body to the applied tidal field. The Love number is dimensionless, and it encodes information about the body's internal structure. We present a relativistic theory of Love numbers, which applies to compact bodies with strong internal gravities; the theory extends and completes a recent work by Flanagan and Hinderer, which revealed that the tidal Love number of a neutron star can be measured by Earth-based gravitational-wave detectors. We consider a spherical body deformed by an external tidal field, and provide precise and meaningful definitions for electric-type and magnetic-type Love numbers; and these are computed for polytropic equations of state. The theory applies to black holes as well, and we find that the relativistic Love numbers of a nonrotating black hole are all zero.

  15. Invitation to number theory second edition

    CERN Document Server

    Ore, Oystein

    2017-01-01

    Number theory is the branch of mathematics concerned with the counting numbers, 1, 2, 3, … and their multiples and factors. Of particular importance are odd and even numbers, squares and cubes, and prime numbers. But in spite of their simplicity, you will meet a multitude of topics in this book: magic squares, cryptarithms, finding the day of the week for a given date, constructing regular polygons, pythagorean triples, and many more. In this revised edition, John Watkins and Robin Wilson have updated the text to bring it in line with contemporary developments. They have added new material on Fermat's Last Theorem, the role of computers in number theory, and the use of number theory in cryptography, and have made numerous minor changes in the presentation and layout of the text and the exercises.

  16. Self-correcting random number generator

    Science.gov (United States)

    Humble, Travis S.; Pooser, Raphael C.

    2016-09-06

    A system and method for generating random numbers. The system may include a random number generator (RNG), such as a quantum random number generator (QRNG) configured to self-correct or adapt in order to substantially achieve randomness from the output of the RNG. By adapting, the RNG may generate a random number that may be considered random regardless of whether the random number itself is tested as such. As an example, the RNG may include components to monitor one or more characteristics of the RNG during operation, and may use the monitored characteristics as a basis for adapting, or self-correcting, to provide a random number according to one or more performance criteria.

  17. Observing Optional Number in DDC Edition 23

    Directory of Open Access Journals (Sweden)

    Mohamad Rotmianto

    2015-04-01

    Full Text Available Dewey Decimal Classification is a most popular classification system in the world because of its completeness and most up-to-date. There are many optional number in this classification system, although it rarely to be discussed even it is important to known well about that optional number, especially  for  a  librarian  as  classifier.  This  paper  is  a  literature  study  about  Dewey  Decimal Classification  Edition  23,  to  describe  about  optional  numbers,  particularly  the  number  in relationship with Indonesia’s subject and discipline. This paper is to avoid misunderstanding in interpreted about optional number among librarians, especially for who that does not understand well about optional numbers.

  18. Voluntary eye movements direct attention on the mental number space.

    Science.gov (United States)

    Ranzini, Mariagrazia; Lisi, Matteo; Zorzi, Marco

    2016-05-01

    Growing evidence suggests that orienting visual attention in space can influence the processing of numerical magnitude, with leftward orienting speeding up the processing of small numbers relative to larger ones and the converse for rightward orienting. The manipulation of eye movements is a convenient way to direct visuospatial attention, but several aspects of the complex relationship between eye movements, attention orienting and number processing remain unexplored. In a previous study, we observed that inducing involuntary, reflexive eye movements by means of optokinetic stimulation affected number processing only when numerical magnitude was task relevant (i.e., during magnitude comparison, but not during parity judgment; Ranzini et al., in J Cogn Psychol 27, 459-470, (2015). Here, we investigated whether processing of task-irrelevant numerical magnitude can be modulated by voluntary eye movements, and whether the type of eye movements (smooth pursuit vs. saccades) would influence this interaction. Participants tracked with their gaze a dot while listening to a digit. The numerical task was to indicate whether the digit was odd or even through non-spatial, verbal responses. The dot could move leftward or rightward either continuously, allowing tracking by smooth pursuit eye movements, or in discrete steps across a series of adjacent locations, triggering a sequence of saccades. Both smooth pursuit and saccadic eye movements similarly affected number processing and modulated response times for large numbers as a function of direction of motion. These findings suggest that voluntary eye movements redirect attention in mental number space and highlight that eye movements should play a key factor in the investigation of number-space interactions.

  19. THE DISCOUNTED REPRODUCTIVE NUMBER FOR EPIDEMIOLOGY

    OpenAIRE

    Reluga, Timothy C.; Medlock, Jan; Galvani, Alison

    2009-01-01

    The basic reproductive number, , and the effective reproductive number, , are commonly used in mathematical epidemiology as summary statistics for the size and controllability of epidemics. However, these commonly used reproductive numbers can be misleading when applied to predict pathogen evolution because they do not incorporate the impact of the timing of events in the life-history cycle of the pathogen. To study evolution problems where the host population size is changing, measur...

  20. Defense Horizons. Number 79, April 2015

    Science.gov (United States)

    2015-04-01

    control number. 1. REPORT DATE APR 2015 2. REPORT TYPE 3. DATES COVERED 00-00-2015 to 00-00-2015 4. TITLE AND SUBTITLE Defense Horizons. Number...on the block number of the aircraft. While the maritime inverse synthetic aper - ture radar is available on the new RQ-4 Block 40, a more accessible...maintains a loiter time of approximately 24 hours. Its specifications match exactly what would be called for in this type of mission. However, unlike the

  1. Conferences on Combinatorial and Additive Number Theory

    CERN Document Server

    2014-01-01

    This proceedings volume is based on papers presented at the Workshops on Combinatorial and Additive Number Theory (CANT), which were held at the Graduate Center of the City University of New York in 2011 and 2012. The goal of the workshops is to survey recent progress in combinatorial number theory and related parts of mathematics. The workshop attracts researchers and students who discuss the state-of-the-art, open problems, and future challenges in number theory.

  2. Alternating sums of reciprocal generalized Fibonacci numbers.

    Science.gov (United States)

    Kuhapatanakul, Kantaphon

    2014-01-01

    Recently Holliday and Komatsu extended the results of Ohtsuka and Nakamura on reciprocal sums of Fibonacci numbers to reciprocal sums of generalized Fibonacci numbers. The aim of this work is to give similar results for the alternating sums of reciprocals of the generalized Fibonacci numbers with indices in arithmetic progression. Finally we note our generalizations of some results of Holliday and Komatsu. Primary 11B37; secondary 11B39.

  3. Smoothed analysis of complex conic condition numbers

    OpenAIRE

    Buergisser, Peter; Cucker, Felipe; Lotz, Martin

    2006-01-01

    Smoothed analysis of complexity bounds and condition numbers has been done, so far, on a case by case basis. In this paper we consider a reasonably large class of condition numbers for problems over the complex numbers and we obtain smoothed analysis estimates for elements in this class depending only on geometric invariants of the corresponding sets of ill-posed inputs. These estimates are for a version of smoothed analysis proposed in this paper which, to the best of our knowledge, appears ...

  4. High Atom Number in Microsized Atom Traps

    Science.gov (United States)

    2015-12-14

    Final Performance Report on ONR Grant N00014-12-1-0608 High atom number in microsized atom traps for the period 15 May 2012 through 14 September...TYPE Final Technical Report 3. DATES COVERED (From - To) 05/15/2012-09/14/2012 4. TITLE AND SUBTITLE High atom number in microsized atom traps...forces for implementing a small-footprint, large-number atom -chip instrument. Bichromatic forces rely on absorption and stimulated emission to produce

  5. Maximum Sunspot Numbers and Active Days

    OpenAIRE

    Heon-Young Chang

    2013-01-01

    Parameters associated with solar minimum have been studied to relate them to solar activity at solar maximum so that one could possibly predict behaviors of an upcoming solar cycle. The number of active days has been known as a reliable indicator of solar activity around solar minimum. Active days are days with sunspots reported on the solar disk. In this work, we have explored the relationship between the sunspot numbers at solar maximum and the characteristics of the monthly number...

  6. Analysis of android random number generator

    OpenAIRE

    Sarıtaş, Serkan

    2013-01-01

    Ankara : The Department of Computer Engineering and the Graduate School of Engineering and Science of Bilkent University, 2013. Thesis (Master's) -- Bilkent University, 2013. Includes bibliographical references leaves 61-65. Randomness is a crucial resource for cryptography, and random number generators are critical building blocks of almost all cryptographic systems. Therefore, random number generation is one of the key parts of secure communication. Random number generatio...

  7. Quality pseudo-random number generator

    International Nuclear Information System (INIS)

    Tarasiuk, J.

    1996-01-01

    The pseudo-random number generator (RNG) was written to match needs of nuclear and high-energy physics computation which in some cases require very long and independent random number sequences. In this random number generator the repetition period is about 10 36 what should be sufficient for all computers in the world. In this article the test results of RNG correlation, speed and identity of computations for PC, Sun4 and VAX computer tests are presented

  8. The Learning Potentials of Number Blocks

    DEFF Research Database (Denmark)

    Majgaard, Gunver; Nielsen, Jacob; Misfeldt, Morten

    2012-01-01

    . The tool is called Number Blocks and it combines physical interaction, learning, and immediate feedback. Number Blocks supports the children's understanding of place value in the sense that it allows them to experiment with creating large numbers. We found the blocks contributed to the learning process...... in several ways. The blocks combined mathematics and play, and they included and supported children at different academic levels. The auditory representation, especially the enhanced rhythmic effects due to using speech synthesis, and the rhythm helped the children to pronounce large numbers. This creates...

  9. Unique Physician Identification Number (UPIN) Directory

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Unique Physician Identification Number (UPIN) Directory contains selected information on physicians, doctors of Osteopathy, limited licensed practitioners and...

  10. Numbers and prior knowledge in sentence comprehension

    Directory of Open Access Journals (Sweden)

    Pedro Macizo

    2013-01-01

    Full Text Available We evaluated whether the comprehension of sentences that contained numerical information could benefit from presenting numbers in Arabic format and from using prior knowledge. Participants read sentences including numbers (Arabic digits or number words while the comprehension accuracy was evaluated. In addition, the sentences were biased or unbiased by people's prior knowledge about quantities. The results showed better comprehension for sentences that contained Arabic digits as compared to number words. Moreover, biased sentences were understood more accurately than unbiased sentences. These results indicate that information about magnitude in sentence context is comprehended better when quantities are presented in Arabic format and when they are associated with participants' world knowledge.

  11. Numbers and other math ideas come alive

    CERN Document Server

    Pappas, Theoni

    2012-01-01

    Most people don't think about numbers, or take them for granted. For the average person numbers are looked upon as cold, clinical, inanimate objects. Math ideas are viewed as something to get a job done or a problem solved. Get ready for a big surprise with Numbers and Other Math Ideas Come Alive. Pappas explores mathematical ideas by looking behind the scenes of what numbers, points, lines, and other concepts are saying and thinking. In each story, properties and characteristics of math ideas are entertainingly uncovered and explained through the dialogues and actions of its math

  12. Coset Group Construction of Multidimensional Number Systems

    Directory of Open Access Journals (Sweden)

    Horia I. Petrache

    2014-07-01

    Full Text Available Extensions of real numbers in more than two dimensions, in particular quaternions and octonions, are finding applications in physics due to the fact that they naturally capture symmetries of physical systems. However, in the conventional mathematical construction of complex and multicomplex numbers multiplication rules are postulated instead of being derived from a general principle. A more transparent and systematic approach is proposed here based on the concept of coset product from group theory. It is shown that extensions of real numbers in two or more dimensions follow naturally from the closure property of finite coset groups adding insight into the utility of multidimensional number systems in describing symmetries in nature.

  13. Soft swimming: exploiting deformable interfaces for low reynolds number locomotion.

    Science.gov (United States)

    Trouilloud, Renaud; Yu, Tony S; Hosoi, A E; Lauga, Eric

    2008-07-25

    Reciprocal movement cannot be used for locomotion at low Reynolds number in an infinite fluid or near a rigid surface. Here we show that this limitation is relaxed for a body performing reciprocal motions near a deformable interface. Using physical arguments and scaling relationships, we show that the nonlinearities arising from reciprocal flow-induced interfacial deformation rectify the periodic motion of the swimmer, leading to locomotion. Such a strategy can be used to move toward, away from, and parallel to any deformable interface as long as the length scales involved are smaller than intrinsic scales, which we identify. A macroscale experiment of flapping motion near a free surface illustrates this new result.

  14. Research Laboratory of Electronic Progress Report Number 135.

    Science.gov (United States)

    1993-06-01

    S.R. Bahl, and J.A. del Alamo. "Une Optoelectronique Ill-V, La Grande Motte, Etude des Niveaux Profonds dand le Transistor France, October 21-23...Chaotic Webs in Ion-orbit Chaos = 1, A = 5). Induced by Waves 2 eE° Sponsors R+wcx..- sin(kx -wt) (1) National Aeronautics and Space Administration where...Report Number 135 • Chapter 1. Plasma Dynamics where F = eEok/(mW2) is the normalized amplitude of amplitudes; second, the chaotic web exists over all

  15. Continental anthropogenic primary particle number emissions

    Science.gov (United States)

    Paasonen, Pauli; Kupiainen, Kaarle; Klimont, Zbigniew; Visschedijk, Antoon; Denier van der Gon, Hugo A. C.; Amann, Markus

    2016-06-01

    Atmospheric aerosol particle number concentrations impact our climate and health in ways different from those of aerosol mass concentrations. However, the global, current and future anthropogenic particle number emissions and their size distributions are so far poorly known. In this article, we present the implementation of particle number emission factors and the related size distributions in the GAINS (Greenhouse Gas-Air Pollution Interactions and Synergies) model. This implementation allows for global estimates of particle number emissions under different future scenarios, consistent with emissions of other pollutants and greenhouse gases. In addition to determining the general particulate number emissions, we also describe a method to estimate the number size distributions of the emitted black carbon particles. The first results show that the sources dominating the particle number emissions are different to those dominating the mass emissions. The major global number source is road traffic, followed by residential combustion of biofuels and coal (especially in China, India and Africa), coke production (Russia and China), and industrial combustion and processes. The size distributions of emitted particles differ across the world, depending on the main sources: in regions dominated by traffic and industry, the number size distribution of emissions peaks in diameters range from 20 to 50 nm, whereas in regions with intensive biofuel combustion and/or agricultural waste burning, the emissions of particles with diameters around 100 nm are dominant. In the baseline (current legislation) scenario, the particle number emissions in Europe, Northern and Southern Americas, Australia, and China decrease until 2030, whereas especially for India, a strong increase is estimated. The results of this study provide input for modelling of the future changes in aerosol-cloud interactions as well as particle number related adverse health effects, e.g. in response to tightening

  16. Continental anthropogenic primary particle number emissions

    Directory of Open Access Journals (Sweden)

    P. Paasonen

    2016-06-01

    Full Text Available Atmospheric aerosol particle number concentrations impact our climate and health in ways different from those of aerosol mass concentrations. However, the global, current and future anthropogenic particle number emissions and their size distributions are so far poorly known. In this article, we present the implementation of particle number emission factors and the related size distributions in the GAINS (Greenhouse Gas–Air Pollution Interactions and Synergies model. This implementation allows for global estimates of particle number emissions under different future scenarios, consistent with emissions of other pollutants and greenhouse gases. In addition to determining the general particulate number emissions, we also describe a method to estimate the number size distributions of the emitted black carbon particles. The first results show that the sources dominating the particle number emissions are different to those dominating the mass emissions. The major global number source is road traffic, followed by residential combustion of biofuels and coal (especially in China, India and Africa, coke production (Russia and China, and industrial combustion and processes. The size distributions of emitted particles differ across the world, depending on the main sources: in regions dominated by traffic and industry, the number size distribution of emissions peaks in diameters range from 20 to 50 nm, whereas in regions with intensive biofuel combustion and/or agricultural waste burning, the emissions of particles with diameters around 100 nm are dominant. In the baseline (current legislation scenario, the particle number emissions in Europe, Northern and Southern Americas, Australia, and China decrease until 2030, whereas especially for India, a strong increase is estimated. The results of this study provide input for modelling of the future changes in aerosol–cloud interactions as well as particle number related adverse health effects, e.g. in response

  17. Estimates of the number of large amplitude gusts

    Energy Technology Data Exchange (ETDEWEB)

    Ramsdell, J.V.

    1978-03-01

    Preliminary estimates are presented of the number of occurrences of large amplitude gusts for use in the design of wind energy conversion systems. Existing turbulence information has been combined with an assumed wind speed distribution to arrive at the estimates. The number of large amplitude gusts per year is treated as a function of the annual mean wind speed and terrain roughness. This treatment is based upon the assumptions that the atmosphere has neutral stability during high winds and that the gustiness is induced by flow over surface roughness elements. Large gusts during thunderstorms and other severe weather phenomena are not treated. The results of the study are presented in tabular form as a function of gust amplitude and hourly average wind speed.

  18. Number-conserving random phase approximation with analytically integrated matrix elements

    International Nuclear Information System (INIS)

    Kyotoku, M.; Schmid, K.W.; Gruemmer, F.; Faessler, A.

    1990-01-01

    In the present paper a number conserving random phase approximation is derived as a special case of the recently developed random phase approximation in general symmetry projected quasiparticle mean fields. All the occurring integrals induced by the number projection are performed analytically after writing the various overlap and energy matrices in the random phase approximation equation as polynomials in the gauge angle. In the limit of a large number of particles the well-known pairing vibration matrix elements are recovered. We also present a new analytically number projected variational equation for the number conserving pairing problem

  19. Variation in the number of EPIYA-C repeats in CagA protein from Colombian Helicobacter pylori strains and its ability to induce hummingbird phenotype in gastric epithelial cells Variación en el número de repeticiones EPIYA-C en la proteína CagA de aislamientos colombianos de Helicobacter pylori y su capacidad para inducir fenotipo colibrí en células epiteliales gástricas

    Directory of Open Access Journals (Sweden)

    María Mercedes Bravo

    2010-08-01

    Full Text Available Introduction. Studies using Western Helicobacter pylori strains have shown that a risk factor for gastric cancer is the number of EPIYA-C motifs in the cytotoxin-associated A protein. CagA is delivered into epithelial cells, where it becomes tyrosine phosphorylated in their EPIYA repeats and induces cytoskeleton rearrangements.
    Objectives. The objective of this study was to evaluate H. pylori cagA positive strains isolated from Colombian patients with gastroduodenal diseases for the number of EPIYA-C repeats in cagA and their ability to induce cytoskeleton rearrangements in epithelial cells.
    Materials and methods. We analyzed the 3' EPIYA repeats region of cagA by PCR in 93 H. pylori cagA positive strains from 49 patients with gastritis, 17 with gastric cancer, and 24 with duodenal ulcer. AGS cells exposed to the various H. pylori isolates were evaluated for rearrangements in their cytoskeleton.
    Results. Strains with one EPIYA-C were the most frequent in gastritis and duodenal ulcer patients. Strains with three EPIYA-C were mainly found in gastric cancer. We found a significantly higher risk of gastric cancer for individuals infected with strains harboring three EPIYA-C motifs (OR=12.4, CI95%: 2.32-66.3. Strains from gastric cancer showed significantly higher percentages of induction of cytoskeleton rearrangements in comparison with those from gastritis (p Mann-Whitney<0.005.
    Conclusions. H. pylori strains with three EPIYA-C repeats can confer an increased risk of cancer to infected individuals.Introducción. En los aislamientos de Helicobacter pylori del hemisferio occidental, se ha observado que el número de repeticiones EPIYA-C en la proteína CagA es un factor de riesgo para cáncer gástrico. La proteína CagA es introducida en la célula epitelial y, posteriormente, es fosforilada en las tirosinas presentes en los motivos EPIYA e induce rearreglos en el citoesqueleto.
    Objetivos. Nuestro propósito fue evaluar el n

  20. Analytic number theory an introductory course

    CERN Document Server

    Bateman, Paul T

    2004-01-01

    This valuable book focuses on a collection of powerful methods ofanalysis that yield deep number-theoretical estimates. Particularattention is given to counting functions of prime numbers andmultiplicative arithmetic functions. Both real variable ("elementary")and complex variable ("analytic") methods are employed.

  1. Lepton number violation searches at the LHC

    CERN Document Server

    Salvucci, Antonio; The ATLAS collaboration

    2017-01-01

    Lepton number is conserved in the Standard Model, therefore, any evidence for its violation would indicate the existence of new physics. This talk presents a review of the latest searches performed at the LHC concerning Lepton Number Violation (LNV) processes in the context of Left-Right Symmetric theory and Seesaw mechanism.

  2. Hello, I am not an NHS number.

    Science.gov (United States)

    Bates, Jane

    2016-09-14

    I was handed a request to return a patient's call and given a name, signs and symptoms and a number with ten digits, starting with a seven. There was no preceding zero, and assuming it must be a mistake I stuck one on, and dialled. The number was unobtainable.

  3. 20 CFR 404.1220 - Identification numbers.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Identification numbers. 404.1220 Section 404.1220 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY... will assign a special identification number to each political subdivision included in that modification...

  4. On the Infinitude of the Prime Numbers

    Indian Academy of Sciences (India)

    wherea,b,c,d, .. . , are the successive terms of any increasing arithmetic progression of positive real numbers. Elementary Results. The next result that we shall need is the so-called fundamental theorem of arithmetic: every positive integer greater than 1 can be expressed in precisely one way as a product of prime numbers.

  5. Inhibition, Conflict Detection, and Number Conservation

    Science.gov (United States)

    Lubin, Amélie; Simon, Grégory; Houdé, Olivier; De Neys, Wim

    2015-01-01

    The acquisition of number conservation is a critical step in children's numerical and mathematical development. Classic developmental studies have established that children's number conservation is often biased by misleading intuitions. However, the precise nature of these conservation errors is not clear. A key question is whether conservation…

  6. When Symbolic Spatial Cues Go before Numbers

    Science.gov (United States)

    Herrera, Amparo; Macizo, Pedro

    2011-01-01

    This work explores the effect of spatial cueing on number processing. Participants performed a parity judgment task. However, shortly before the target number, a cue (arrow pointing to left, arrow pointing to right or a cross) was centrally presented. In Experiment 1, in which responses were lateralized, the cue direction modulated the interaction…

  7. On the Concept Image of Complex Numbers

    Science.gov (United States)

    Nordlander, Maria Cortas; Nordlander, Edvard

    2012-01-01

    A study of how Swedish students understand the concept of complex numbers was performed. A questionnaire was issued reflecting the student view of own perception. Obtained answers show a variety of concept images describing how students adopt the concept of complex numbers. These concept images are classified into four categories in order to…

  8. MORPHOLOGY AND CHROMOSOME NUMBERS OF Gongronema ...

    African Journals Online (AJOL)

    journal

    Morphology and chromosome numbers than one nucleus per cell (Partanen, 1963). Polyploidy in some instances is advantageous as it affects plant part sizes like larger leaf areas, flowers and fruits (Walker et al. 2005; El-. Ferchichi et al. 2006; Samiha et al. 2009). The higher number of viable seeds per follicle and matured ...

  9. Neural correlates of merging number words.

    Science.gov (United States)

    Hung, Yi-Hui; Pallier, Christophe; Dehaene, Stanislas; Lin, Yi-Chen; Chang, Acer; Tzeng, Ovid J-L; Wu, Denise H

    2015-11-15

    Complex number words (e.g., "twenty two") are formed by merging together several simple number words (e.g., "twenty" and "two"). In the present study, we explored the neural correlates of this operation and investigated to what extent it engages brain areas involved processing numerical quantity and linguistic syntactic structure. Participants speaking two typologically distinct languages, French and Chinese, were required to read aloud sequences of simple number words while their cerebral activity was recorded by functional magnetic resonance imaging. Each number word could either be merged with the previous ones (e.g., 'twenty three') or not (e.g., 'three twenty'), thus forming four levels ranging from lists of number words to complex numerals. When a number word could be merged with the preceding ones, it was named faster than when it could not. Neuroimaging results showed that the number of merges correlated with activation in the left inferior frontal gyrus and in the left inferior parietal lobule. Consistent findings across Chinese and French participants suggest that these regions serve as the neural bases for forming complex number words in different languages. Copyright © 2015 Elsevier Inc. All rights reserved.

  10. Deafness for the Meanings of Number Words

    Science.gov (United States)

    Cano, Agnes; Rapp, Brenda; Costa, Albert; Juncadella, Montserrat

    2008-01-01

    We describe the performance of an aphasic individual who showed a selective impairment affecting his comprehension of auditorily presented number words and not other word categories. His difficulty in number word comprehension was restricted to the auditory modality, given that with visual stimuli (written words, Arabic numerals and pictures) his…

  11. Search for lepton-family-number nonconservation

    International Nuclear Information System (INIS)

    Hoffman, C.M.

    1986-01-01

    A review of the status of lepton-family-number nonconservation is given. After a brief historical and theoretical discussion, a description of how experimental searches for lepton-family-number nonconservation are performed is presented. Finally, a summary of the results from past experiments and prospects for future experiments is given

  12. Fostering At-Risk Preschoolers' Number Sense

    Science.gov (United States)

    Baroody, Arthur; Eiland, Michael; Thompson, Bradley

    2009-01-01

    Research Findings: A 9-month study served to evaluate the effectiveness of a pre-kindergarten number sense curriculum. Phase 1 of the intervention involved manipulative-, game-based number sense instruction; Phase 2, computer-aided mental-arithmetic training with the simplest sums. Eighty 4- and 5-year-olds at risk for school failure were randomly…

  13. Atomic Fisher information versus atomic number

    International Nuclear Information System (INIS)

    Nagy, A.; Sen, K.D.

    2006-01-01

    It is shown that the Thomas-Fermi Fisher information is negative. A slightly more sophisticated model proposed by Gaspar provides a qualitatively correct expression for the Fisher information: Gaspar's Fisher information is proportional to the two-third power of the atomic number. Accurate numerical calculations show an almost linear dependence on the atomic number

  14. Cellular Automata Rules and Linear Numbers

    OpenAIRE

    Nayak, Birendra Kumar; Sahoo, Sudhakar; Biswal, Sagarika

    2012-01-01

    In this paper, linear Cellular Automta (CA) rules are recursively generated using a binary tree rooted at "0". Some mathematical results on linear as well as non-linear CA rules are derived. Integers associated with linear CA rules are defined as linear numbers and the properties of these linear numbers are studied.

  15. Estimating Avogadro's number from skylight and airlight

    Science.gov (United States)

    Pesic, Peter

    2005-01-01

    Naked-eye determinations of the visual range yield order-of-magnitude estimates of Avogadro's number, using an argument of Rayleigh. Alternatively, by looking through a cardboard tube, we can compare airlight and skylight and give another estimate of this number using the law of atmospheres.

  16. Hacking DNA copy number for circuit engineering.

    Science.gov (United States)

    Wu, Feilun; You, Lingchong

    2017-07-27

    DNA copy number represents an essential parameter in the dynamics of synthetic gene circuits but typically is not explicitly considered. A new study demonstrates how dynamic control of DNA copy number can serve as an effective strategy to program robust oscillations in gene expression circuits.

  17. IEEE Standard for Floating Point Numbers

    Indian Academy of Sciences (India)

    IAS Admin

    This is a conservative definition used by industry. In MATLAB, machine epsilon is as defined above. However, academics define machine epsilon as the upper bound of the relative error when numbers are rounded. Thus, for 32-bit floating point numbers, the machine epsilon is 2–23/2. 5.96 ×10–8. The machine epsilon is ...

  18. Factors Influencing Number of Physiotherapy Treatment Sessions ...

    African Journals Online (AJOL)

    Little is known about the influence of physiotherapists' characteristics and treatment modalities on the number of treatment sessions in Nigeria. This study was designed to evaluate the factors influencing the number of treatment sessions for patients with low back pain (LBP). Three hundred and eleven practising ...

  19. 41 CFR 105-1.109 - Numbering.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Numbering. 105-1.109 Section 105-1.109 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION 1-INTRODUCTION 1.1-Regulations System § 105-1.109 Numbering. ...

  20. 7 CFR 46.20 - Lot numbers.

    Science.gov (United States)

    2010-01-01

    ... and entered on all sales tickets identifying and segregating the sales from the various shipments on hand. The lot number shall be entered on the sales tickets by the salesmen at the time of sale or by the produce dispatcher, and not by bookkeepers or others after the sales have been made. No lot number...

  1. On contact numbers in random rod packings

    NARCIS (Netherlands)

    Wouterse, A.; Luding, Stefan; Philipse, A.P.

    2009-01-01

    Random packings of non-spherical granular particles are simulated by combining mechanical contraction and molecular dynamics, to determine contact numbers as a function of density. Particle shapes are varied from spheres to thin rods. The observed contact numbers (and packing densities) agree well

  2. Comments on nonparametric predictions of sunspot numbers

    DEFF Research Database (Denmark)

    Jensen, J.L.

    1993-01-01

    Recent results of Cerrito (1990) are criticized, and the level of unexplainable noise in the observed series of sunspot numbers is discussed.......Recent results of Cerrito (1990) are criticized, and the level of unexplainable noise in the observed series of sunspot numbers is discussed....

  3. The Ramsey Numbers of Paths Versus Fans

    NARCIS (Netherlands)

    Salman, M.; Broersma, Haitze J.; Faigle, U.; Hurink, Johann L.; Pickl, Stefan; Woeginger, Gerhard

    2003-01-01

    For two given graphs G and H, the Ramsey number R(G,H) is the smallest positive integer p such that for every graph F on p vertices the following holds: either F contains G as a subgraph or the complement of F contains H as a subgraph. In this paper, we study the Ramsey numbers R(Pn,Fm), where Pn is

  4. Ramsey numbers and adiabatic quantum computing.

    Science.gov (United States)

    Gaitan, Frank; Clark, Lane

    2012-01-06

    The graph-theoretic Ramsey numbers are notoriously difficult to calculate. In fact, for the two-color Ramsey numbers R(m,n) with m, n≥3, only nine are currently known. We present a quantum algorithm for the computation of the Ramsey numbers R(m,n). We show how the computation of R(m,n) can be mapped to a combinatorial optimization problem whose solution can be found using adiabatic quantum evolution. We numerically simulate this adiabatic quantum algorithm and show that it correctly determines the Ramsey numbers R(3,3) and R(2,s) for 5≤s≤7. We then discuss the algorithm's experimental implementation, and close by showing that Ramsey number computation belongs to the quantum complexity class quantum Merlin Arthur.

  5. A conversational introduction to algebraic number theory

    CERN Document Server

    Pollack, Paul

    2017-01-01

    Gauss famously referred to mathematics as the "queen of the sciences" and to number theory as the "queen of mathematics". This book is an introduction to algebraic number theory, meaning the study of arithmetic in finite extensions of the rational number field \\mathbb{Q}. Originating in the work of Gauss, the foundations of modern algebraic number theory are due to Dirichlet, Dedekind, Kronecker, Kummer, and others. This book lays out basic results, including the three "fundamental theorems": unique factorization of ideals, finiteness of the class number, and Dirichlet's unit theorem. While these theorems are by now quite classical, both the text and the exercises allude frequently to more recent developments. In addition to traversing the main highways, the book reveals some remarkable vistas by exploring scenic side roads. Several topics appear that are not present in the usual introductory texts. One example is the inclusion of an extensive discussion of the theory of elasticity, which provides a precise w...

  6. Topics from the theory of numbers

    CERN Document Server

    Grosswald, Emil

    1984-01-01

    Many of the important and creative developments in modern mathematics resulted from attempts to solve questions that originate in number theory. The publication of Emil Grosswald’s classic text presents an illuminating introduction to number theory. Combining the historical developments with the analytical approach, Topics from the Theory of Numbers offers the reader a diverse range of subjects to investigate, including: * divisibility * congruences * the Riemann zeta function * Diophantine equations and Fermat’s conjecture * the theory of partitions Comprehensive in nature, Topics from the Theory of Numbers is an ideal text for advanced undergraduates and graduate students alike. "In my opinion it is excellent. It is carefully written and represents clearly a work of a scholar who loves and understands his subject. One can only wish more authors would take such pains and would be as good and honest expositors as Grosswald." — Marc Kac "This book is designed for use in a first course in number theory at...

  7. Complex numbers from A to Z

    CERN Document Server

    Andreescu, Titu

    2014-01-01

    It is impossible to imagine modern mathematics without complex numbers. The second edition of Complex Numbers from A to … Z introduces the reader to this fascinating subject that, from the time of L. Euler, has become one of the most utilized ideas in mathematics. The exposition concentrates on key concepts and then elementary results concerning these numbers. The reader learns how complex numbers can be used to solve algebraic equations and to understand the geometric interpretation of complex numbers and the operations involving them. The theoretical parts of the book are augmented with rich exercises and problems at various levels of difficulty. Many new problems and solutions have been added in this second edition. A special feature of the book is the last chapter, a selection of outstanding Olympiad and other important mathematical contest problems solved by employing the methods already presented. The book reflects the unique experience of the authors. It distills a vast mathematical literature, most ...

  8. Random numbers spring from alpha decay

    International Nuclear Information System (INIS)

    Frigerio, N.A.; Sanathanan, L.P.; Morley, M.; Clark, N.A.; Tyler, S.A.

    1980-05-01

    Congruential random number generators, which are widely used in Monte Carlo simulations, are deficient in that the number they generate are concentrated in a relatively small number of hyperplanes. While this deficiency may not be a limitation in small Monte Carlo studies involving a few variables, it introduces a significant bias in large simulations requiring high resolution. This bias was recognized and assessed during preparations for an accident analysis study of nuclear power plants. This report describes a random number device based on the radioactive decay of alpha particles from a 235 U source in a high-resolution gas proportional counter. The signals were fed to a 4096-channel analyzer and for each channel the frequency of signals registered in a 20,000-microsecond interval was recorded. The parity bits of these frequency counts (0 for an even count and 1 for an odd count) were then assembled in sequence to form 31-bit binary random numbers and transcribed to a magnetic tape. This cycle was repeated as many times as were necessary to create 3 million random numbers. The frequency distribution of counts from the present device conforms to the Brockwell-Moyal distribution, which takes into account the dead time of the counter (both the dead time and decay constant of the underlying Poisson process were estimated). Analysis of the count data and tests of randomness on a sample set of the 31-bit binary numbers indicate that this random number device is a highly reliable source of truly random numbers. Its use is, therefore, recommended in Monte Carlo simulations for which the congruential pseudorandom number generators are found to be inadequate. 6 figures, 5 tables

  9. Doubly stratified mixed convection flow of Maxwell nanofluid with heat generation/absorption

    Energy Technology Data Exchange (ETDEWEB)

    Abbasi, F.M., E-mail: abbasisarkar@gmail.com [Department of Mathematics, Comsats Institute of Information Technology, Islamabad 44000 (Pakistan); Shehzad, S.A. [Department of Mathematics, Comsats Institute of Information Technology, Sahiwal 57000 (Pakistan); Hayat, T. [Department of Mathematics, Quaid-i-Azam University, 45320, Islamabad 44000 (Pakistan); NAAM Research Group, Department of Mathematics, Faculty of Science, King Abdulaziz University, Jeddah 21589 (Saudi Arabia); Ahmad, B. [NAAM Research Group, Department of Mathematics, Faculty of Science, King Abdulaziz University, Jeddah 21589 (Saudi Arabia)

    2016-04-15

    Magnetohydrodynamic (MHD) doubly stratified flow of Maxwell nanofluid in presence of mixed convection is analyzed in this article. Effects of thermophoresis, Brownian motion and heat generation/absorption are present. The flow is induced due to linear stretching of sheet. Mathematical formulation is made under boundary layer approach. Expressions of velocity, temperature and nanoparticles concentration are developed. The obtained results are plotted and discussed to examine the variations in temperature and nanoparticles concentration due to different physical parameters. Numerical computations are made to obtain the values of local Nusselt and Sherwood numbers. Impact of sundry parameters on the flow quantities is analyzed graphically. - Highlights: • Double stratified flow of Maxwell nanofluid with mixed convection is modeled. • Thermophoresis and Brownian motion effects are encountered. • Computations are made to obtain the solution expressions. • Numerical values of local Nusselt and Sherwood numbers are computed and examined.

  10. An optimal study for Darcy-Forchheimer flow with generalized Fourier's and Fick's laws

    Science.gov (United States)

    Hayat, Tasawar; Haider, Farwa; Muhammad, Taseer; Alsaedi, Ahmed

    This article addresses boundary-layer flow of third grade fluid saturating a non-Darcy porous medium. Induced flow is by a stretchable surface. Flow in porous media is described by employing the Darcy-Forchheimer based model. Generalized versions of Fourier's and Fick's laws via Cattaneo-Christov double diffusion expressions are utilized. Transformation method is employed for reduction process of nonlinear partial differential systems into the nonlinear ordinary differential systems. Optimal homotopy analysis method (OHAM) develops the computations. The optimal values of nonzero auxiliary parameters are computed and analyzed. The optimal solutions of temperature and concentration fields are presented through the plots. The skin friction coefficient and local Nusselt and Sherwood numbers are also studied through numerical data. Our results reveal that the local Nusselt and Sherwood numbers are higher for larger values of thermal and concentration relaxation parameters.

  11. Anomalous quantum numbers and topological properties of field theories

    International Nuclear Information System (INIS)

    Polychronakos, A.P.

    1987-01-01

    We examine the connection between anomalous quantum numbers, symmetry breaking patterns and topological properties of some field theories. The main results are the following: In three dimensions the vacuum in the presence of abelian magnetic field configurations behaves like a superconductor. Its quantum numbers are exactly calculable and are connected with the Atiyah-Patodi-Singer index theorem. Boundary conditions, however, play a nontrivial role in this case. Local conditions were found to be physically preferable than the usual global ones. Due to topological reasons, only theories for which the gauge invariant photon mass in three dimensions obeys a quantization condition can support states of nonzero magnetic flux. For similar reasons, this mass induces anomalous angular momentum quantum numbers to the states of the theory. Parity invariance and global flavor symmetry were shown to be incompatible in such theories. In the presence of mass less flavored fermions, parity will always break for an odd number of fermion flavors, while for even fermion flavors it may not break but only at the expense of maximally breaking the flavor symmetry. Finally, a connection between these theories and the quantum Hall effect was indicated

  12. Overfitting Bayesian Mixture Models with an Unknown Number of Components.

    Directory of Open Access Journals (Sweden)

    Zoé van Havre

    Full Text Available This paper proposes solutions to three issues pertaining to the estimation of finite mixture models with an unknown number of components: the non-identifiability induced by overfitting the number of components, the mixing limitations of standard Markov Chain Monte Carlo (MCMC sampling techniques, and the related label switching problem. An overfitting approach is used to estimate the number of components in a finite mixture model via a Zmix algorithm. Zmix provides a bridge between multidimensional samplers and test based estimation methods, whereby priors are chosen to encourage extra groups to have weights approaching zero. MCMC sampling is made possible by the implementation of prior parallel tempering, an extension of parallel tempering. Zmix can accurately estimate the number of components, posterior parameter estimates and allocation probabilities given a sufficiently large sample size. The results will reflect uncertainty in the final model and will report the range of possible candidate models and their respective estimated probabilities from a single run. Label switching is resolved with a computationally light-weight method, Zswitch, developed for overfitted mixtures by exploiting the intuitiveness of allocation-based relabelling algorithms and the precision of label-invariant loss functions. Four simulation studies are included to illustrate Zmix and Zswitch, as well as three case studies from the literature. All methods are available as part of the R package Zmix, which can currently be applied to univariate Gaussian mixture models.

  13. Overfitting Bayesian Mixture Models with an Unknown Number of Components.

    Science.gov (United States)

    van Havre, Zoé; White, Nicole; Rousseau, Judith; Mengersen, Kerrie

    2015-01-01

    This paper proposes solutions to three issues pertaining to the estimation of finite mixture models with an unknown number of components: the non-identifiability induced by overfitting the number of components, the mixing limitations of standard Markov Chain Monte Carlo (MCMC) sampling techniques, and the related label switching problem. An overfitting approach is used to estimate the number of components in a finite mixture model via a Zmix algorithm. Zmix provides a bridge between multidimensional samplers and test based estimation methods, whereby priors are chosen to encourage extra groups to have weights approaching zero. MCMC sampling is made possible by the implementation of prior parallel tempering, an extension of parallel tempering. Zmix can accurately estimate the number of components, posterior parameter estimates and allocation probabilities given a sufficiently large sample size. The results will reflect uncertainty in the final model and will report the range of possible candidate models and their respective estimated probabilities from a single run. Label switching is resolved with a computationally light-weight method, Zswitch, developed for overfitted mixtures by exploiting the intuitiveness of allocation-based relabelling algorithms and the precision of label-invariant loss functions. Four simulation studies are included to illustrate Zmix and Zswitch, as well as three case studies from the literature. All methods are available as part of the R package Zmix, which can currently be applied to univariate Gaussian mixture models.

  14. Number Worlds: Visual and Experimental Access to Elementary Number Theory Concepts

    Science.gov (United States)

    Sinclair, Nathalie; Zazkis, Rina; Liljedahl, Peter

    2004-01-01

    Recent research demonstrates that many issues related to the structure of natural numbers and the relationship among numbers are not well grasped by students. In this article, we describe a computer-based learning environment called "Number Worlds" that was designed to support the exploration of elementary number theory concepts by…

  15. Alternative analysis: the prime numbers theory and an extension of the real numbers set

    OpenAIRE

    Sukhotin A.; Zvyagin M.

    2016-01-01

    Here we consider the theory of prime numbers at a new methodology. The theory of prime numbers is one of the most ancient mathematical branches. We found an estimate of the all prime numbers sum using the notions of infinite lager numbers and infinitely small numbers, farther we estimated the value of the maximal prime number. We proved that Hardy–Littlewood Hypothesis has the positive decision too. The infinite small numbers define a new methodology of the well–known function o(x) applicatio...

  16. Bernoulli-Carlitz and Cauchy-Carlitz numbers with Stirling-Carlitz numbers

    OpenAIRE

    Kaneko, Hajime; Komatsu, Takao

    2017-01-01

    Recently, the Cauchy-Carlitz number was defined as the counterpart of the Bernoulli-Carlitz number. Both numbers can be expressed explicitly in terms of so-called Stirling-Carlitz numbers. In this paper, we study the second analogue of Stirling-Carlitz numbers and give some general formulae, including Bernoulli and Cauchy numbers in formal power series with complex coefficients, and Bernoulli-Carlitz and Cauchy-Carlitz numbers in function fields. We also give some applications of Hasse-Teichm...

  17. Low Nephron Number and Its Clinical Consequences

    Directory of Open Access Journals (Sweden)

    Valerie A. Luyckx

    2011-10-01

    Full Text Available decades ago, that developmental programming of the kidney impacts an individual’s risk for hypertension and renal disease in later life. Low birth weight is the strongest current clinical surrogate marker for an adverse intrauterine environment and, based on animal and human studies, is associated with a low nephron number. Other clinical correlates of low nephron number include female gender, short adult stature, small kidney size, and prematurity. Low nephron number in Caucasian and Australian Aboriginal subjects has been shown to be associated with higher blood pressures, and, conversely, hypertension is less prevalent in individuals with higher nephron numbers. In addition to nephron number, other programmed factors associated with the increased risk of hypertension include salt sensitivity, altered expression of renal sodium transporters, altered vascular reactivity, and sympathetic nervous system overactivity. Glomerular volume is universally found to vary inversely with nephron number, suggesting a degree of compensatory hypertrophy and hyperfunction in the setting of a low nephron number. This adaptation may become overwhelmed in the setting of superimposed renal insults, e.g. diabetes mellitus or rapid catch-up growth, leading to the vicious cycle of on-going hyperfiltration, proteinuria, nephron loss and progressive renal functional decline. Many millions of babies are born with low birth weight every year, and hypertension and renal disease prevalences are increasing around the globe. At present, little can be done clinically to augment nephron number; therefore adequate prenatal care and careful postnatal nutrition are crucial to optimize an individual’s nephron number during development and potentially to stem the tide of the growing cardiovascular and renal disease epidemics worldwide.

  18. Numbers at work a cultural perspective

    CERN Document Server

    Taschner , Rudolf

    2007-01-01

    Drawing primarily from historical examples, this book explains the tremendous role that numbers and, in particular, mathematics play in all aspects of our civilization and culture. The lively style and illustrative examples will engage the reader who wants to understand the many ways in which mathematics enables science, technology, art, music, politics, and rational foundations of human thought. Each chapter focuses on the influence of mathematics in a specific field and on a specific historical figure, such as ""Pythagoras: Numbers and Symbol""; ""Bach: Numbers and Music""; ""Descartes: Numb

  19. Algebraic Geometry and Number Theory Summer School

    CERN Document Server

    Sarıoğlu, Celal; Soulé, Christophe; Zeytin, Ayberk

    2017-01-01

    This lecture notes volume presents significant contributions from the “Algebraic Geometry and Number Theory” Summer School, held at Galatasaray University, Istanbul, June 2-13, 2014. It addresses subjects ranging from Arakelov geometry and Iwasawa theory to classical projective geometry, birational geometry and equivariant cohomology. Its main aim is to introduce these contemporary research topics to graduate students who plan to specialize in the area of algebraic geometry and/or number theory. All contributions combine main concepts and techniques with motivating examples and illustrative problems for the covered subjects. Naturally, the book will also be of interest to researchers working in algebraic geometry, number theory and related fields.

  20. Topological quantum numbers in nonrelativistic physics

    CERN Document Server

    Thouless, David James

    1998-01-01

    Topological quantum numbers are distinguished from quantum numbers based on symmetry because they are insensitive to the imperfections of the systems in which they are observed. They have become very important in precision measurements in recent years, and provide the best measurements of voltage and electrical resistance. This book describes the theory of such quantum numbers, starting with Dirac's argument for the quantization of electric charge, and continuing with discussions on the helium superfluids, flux quantization and the Josephson effect in superconductors, the quantum Hall effect,

  1. Standard random number generation for MBASIC

    Science.gov (United States)

    Tausworthe, R. C.

    1976-01-01

    A machine-independent algorithm is presented and analyzed for generating pseudorandom numbers suitable for the standard MBASIC system. The algorithm used is the polynomial congruential or linear recurrence modulo 2 method. Numbers, formed as nonoverlapping adjacent 28-bit words taken from the bit stream produced by the formula a sub m + 532 = a sub m + 37 + a sub m (modulo 2), do not repeat within the projected age of the solar system, show no ensemble correlation, exhibit uniform distribution of adjacent numbers up to 19 dimensions, and do not deviate from random runs-up and runs-down behavior.

  2. Recognition of the smart card iconic numbers

    Directory of Open Access Journals (Sweden)

    Xin Xue Shi

    2016-01-01

    Full Text Available Manual way of recognizing and inputting the smart card iconic numbers leads to much time consuming, high resources consuming and low accuracy. This paper presents a new automatic method based on the technology of computer vision, including Harr operator for face detection, Fast operator for number location, image binarization, character segmentation and BP neural network for number recognition. Experimental results on 100 ID cards show that by adjusting the parameters of the BP neural network properly, the recognition accuracy is more than 99%, and the recognition time for each ID card is within 0.05 seconds.

  3. Boundary Layer Fluid Flow in a Channel with Heat Source, Soret ...

    African Journals Online (AJOL)

    The skin friction coefficient, Nusselt number and Sherwood number were also depicted on tables. The skin friction coefficient increased with the increase in material parameters ƒÜ ,Pr,Sc,Sr,Gc,andmt and decreased with increase of material parameters s,Gr,M,andƒ× . Increasing effects of Pr, decreased the Nusselt number ...

  4. Flux scaling: Ultimate regime

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. Flux scaling: Ultimate regime. With the Nusselt number and the mixing length scales, we get the Nusselt number and Reynolds number (w'd/ν) scalings: and or. and. scaling expected to occur at extremely high Ra Rayleigh-Benard convection. Get the ultimate regime ...

  5. Numerical analysis of 3D micropolar nanofluid flow induced by an exponentially stretching surface embedded in a porous medium

    Science.gov (United States)

    Subhani, M.; Nadeem, S.

    2017-10-01

    The present article is devoted to probe the behavior of a three-dimensional micropolar nanofluid over an exponentially stretching surface in a porous medium. The mathematical model is constructed in the form of partial differential equations using the boundary layer approach. Then by employing similarity transformations, the modelled partial differential equations are transformed to ordinary differential equations. The solution of subsequent ODEs is derived by utilizing the BVP-4C technique alongside the shooting scheme. The graphical illustrations are presented to interpret the salient features of pertinent physical parameters on the concerned profiles for different kinds of nanoparticles, namely copper, titania and alumina with water as the base fluid. For a better understanding of the fluid flow, the numerical variation in the local skin friction coefficients, Cfx and Cfy , and local Nusselt number is analyzed through tables. We can see, from the present study, that the omission of porous matrix enhances the flow of the fluid. Microrotation has a decreasing impact on the skin friction whereas it increases the rate of the heat transfer of the nanofluid.

  6. Is the number of registered abortions in Serbia realistic?

    Directory of Open Access Journals (Sweden)

    Rašević Mirjana

    2008-01-01

    Full Text Available Ever since the 1990's the number of registered abortions in Serbia has been decreasing from year to year. Are the abortion data of the Public Health Institute complete? In other words, has there been a qualitative shift in the sphere of reproductive behavior of Serbia's population in the last two decades? This paper deals with the raised question in three ways. First, in an indirect way, by analyzing whether a radical change in birth control since the 1990's has been possible, having in mind the complexity of the abortion issue in Serbia, as well as the broad social context regarding the last decade of the last century and beginning of this one. The second way deals more directly with the quality of the official data on abortions. Namely, the great decrease in the number of induced abortions, theoretically observed, may be a consequence of the increased level of births, or possibly acceleration in the birth control transition from the use of traditional and inefficient contraception to the usage of modern and efficient methods and means for conception control. For this reason, population fertility trends were analyzed, with a special review on the time period from the 1990's till present day and the results of the available surveyed researches on the structure of contraception usage in order to determine whether objective assumptions exist for the decrease in the number of induced abortions or not. The third way to reach an answer to the raised question in the title was attempted by estimating the scope of induced abortions. In that sense, relevant literature was consulted and the Westoff method chosen for calculating the rate of total abortions in Serbia (excluding Kosovo and Metohia in the year 2006. After examining the set task from all three sides, there seemed to be no doubt that the official data on the number of abortions in Serbia are not realistic. The basic reason for incomplete official data on abortions seems to be the fact that in

  7. Complex Binary Number System Algorithms and Circuits

    CERN Document Server

    Jamil, Tariq

    2013-01-01

    This book is a compilation of the entire research work on the topic of Complex Binary Number System (CBNS) carried out by the author as the principal investigator and members of his research groups at various universities during the years 1992-2012. Pursuant to these efforts spanning several years, the realization of CBNS as a viable alternative to represent complex numbers in an 'all-in-one' binary number format has become possible and efforts are underway to build computer hardware based on this unique number system. It is hoped that this work will be of interest to anyone involved in computer arithmetic and digital logic design and kindle renewed enthusiasm among the engineers working in the areas of digital signal and image processing for developing newer and efficient algorithms and techniques incorporating CBNS.

  8. Muon number nonconservation in gauge theories

    International Nuclear Information System (INIS)

    Cheng, T.P.; Li, L.F.

    1977-01-01

    The question of separate conservation of muon and electron number is considered in the context of unified gauge theories of weak and electromagnetic interactions. Theories with heavy neutral leptons, Higgs scalars, and doubly charged heavy leptons are discussed. 28 references

  9. Distribution function of faint galaxy numbers

    International Nuclear Information System (INIS)

    Fesenko, L.M.

    1981-01-01

    The Lick observatory counts of galaxies are considered. The distribution of number of galaxies in elementary regions (ER) of 1 degx1 deg is investigated. Each field of 6 degx6 deg was treated separately At b>40 deg the probab+lity to observe of n galaxies in ER is an exponential decreasing function of n, if unequality n> were fulfilled. The mean apparent multiplicity of a galaxy (2.8+-0.9) was derived. The galaxy number distribution was simple model for the number of various systems of galaxies. The supperclustering of galaxies was not introduced. Based on that model the approximate expression for galaxy number distribution was considered and was compared with observed distributions. The agreement between these distributions become better with reducing of the interstellar absorption of light

  10. Chaotic behaviour of high Mach number flows

    Science.gov (United States)

    Varvoglis, H.; Ghosh, S.

    1985-01-01

    The stability of the super-Alfvenic flow of a two-fluid plasma model with respect to the Mach number and the angle between the flow direction and the magnetic field is investigated. It is found that, in general, a large scale chaotic region develops around the initial equilibrium of the laminar flow when the Mach number exceeds a certain threshold value. After reaching a maximum the size of this region begins shrinking and goes to zero as the Mach number tends to infinity. As a result high Mach number flows in time independent astrophysical plasmas may lead to the formation of 'quasi-shocks' in the presence of little or no dissipation.

  11. The Power of Numbers in Global Governance

    DEFF Research Database (Denmark)

    Krause Hansen, Hans; Mühlen-Schulte, Arthur

    2012-01-01

    at a distance in the global political economy. It argues that the use of numbers in global governance should not be regarded only as a platform for knowledge sharing and learning. More than this, it needs to be understood in broader terms as a mechanism of inclusion and exclusion from complex social hierarchies......The deployment of numbers have become a sine qua non in governance practices worldwide in recent decades. But the reasons behind this development and its implications for governance practices have not been systematically researched and theorised. This introductory article provides a short overview...... of the historical and contemporary role of numbers in different governance settings. It includes a discussion of the capacity of numbers to foster social identities, relations and truths across national boundaries, to construct issue areas and to enable various modes of surveillance, communication and action...

  12. Bone Mass Measurement: What the Numbers Mean

    Science.gov (United States)

    ... the Test Do? The T-Score World Health Organization Definitions Based on Bone Density Levels Low Bone Mass ... number, the more severe the osteoporosis. World Health Organization Definitions Based on Bone Density Levels Level Definition Normal ...

  13. The rise of number agreement in Nheengatu

    Directory of Open Access Journals (Sweden)

    Aline da Cruz

    Full Text Available Abstract: Number agreement systems often present traces of older elements common to different languages of the same family; thus, their emergence is difficult to reconstruct. One possible origin of such systems is the grammaticalization of plural words into bound morphemes, which, as a result of a long process, develop into agreement markers and may become obligatory. Various investigations have provided evidence for this hypothesis. However, the complete process of change from a system with no number as grammatical category into a number agreement system in a single language has not been documented. This paper analyses documents covering different stages of the development of the Nheengatu language from Tupinambá in order to observe how the number agreement system emerged in modern Nheengatu. By doing so, this paper supports the idea that grammaticalization may have occurred rapidly in intense contact situations.

  14. Gateway Newsletter. Volume 14. Number 1, 2003

    National Research Council Canada - National Science Library

    Johnston, Judith

    2003-01-01

    .... The Human Systems Information Analysis Center (HSIAC) is the gateway to worldwide sources of up-to-date human systems information for designers, engineers, researchers, and number factors specialists...

  15. Introduction to the geometry of complex numbers

    CERN Document Server

    Deaux, Roland

    2008-01-01

    Geared toward readers unfamiliar with complex numbers, this text explains how to solve problems that frequently arise in the applied sciences and emphasizes constructions related to algebraic operations. 1956 edition.

  16. Opening the Door on Triangular Numbers

    Science.gov (United States)

    McMartin, Kimberley; McMaster, Heather

    2016-01-01

    As an alternative to looking solely at linear functions, a three-lesson learning progression developed for Year 6 students that incorporates triangular numbers to develop children's algebraic thinking is described and evaluated.

  17. Generation of pseudo-random numbers

    Science.gov (United States)

    Howell, L. W.; Rheinfurth, M. H.

    1982-01-01

    Practical methods for generating acceptable random numbers from a variety of probability distributions which are frequently encountered in engineering applications are described. The speed, accuracy, and guarantee of statistical randomness of the various methods are discussed.

  18. A brief introduction to particle number estimation

    DEFF Research Database (Denmark)

    Dorph-Petersen, Karl-Anton; Nyengaard, Jens Randel; Gundersen, Hans Jørgen Gottlieb

    1998-01-01

    The principle of particle number estimation using the disector is described emphasising the practical similarities and differences in the application of the principle in biomedicine and non-biological sciences....

  19. Microcomputer-Assisted Discoveries: Random Numbers.

    Science.gov (United States)

    Kimberling, Clark

    1983-01-01

    A programing contest was designed to promote interest in mathematical randomness. Student-developed programs making clever uses of random numbers are presented. Modifications users might make are suggested. (MNS)

  20. Using Random Numbers in Science Research Activities.

    Science.gov (United States)

    Schlenker, Richard M.; And Others

    1996-01-01

    Discusses the importance of science process skills and describes ways to select sets of random numbers for selection of subjects for a research study in an unbiased manner. Presents an activity appropriate for grades 5-12. (JRH)

  1. Clinching First Place: Calculating the Magic Number.

    Science.gov (United States)

    Quinn, Robert J.

    2000-01-01

    Describes a lesson plan in which students apply their mathematical intuition to determine win-loss possibilities of teams in a sports league and develop a formula for calculating the magic number for clinching first place. (YDS)

  2. Hodge numbers for all CICY quotients

    Energy Technology Data Exchange (ETDEWEB)

    Constantin, Andrei [Department of Physics and Astronomy, Uppsala University, SE-751 20, Uppsala (Sweden); Gray, James [Physics Department, Robeson Hall, Virginia Tech,Blacksburg, VA 24061 (United States); Lukas, Andre [Rudolf Peierls Centre for Theoretical Physics, Oxford University,1 Keble Road, Oxford, OX1 3NP (United Kingdom)

    2017-01-02

    We present a general method for computing Hodge numbers for Calabi-Yau manifolds realised as discrete quotients of complete intersections in products of projective spaces. The method relies on the computation of equivariant cohomologies and is illustrated for several explicit examples. In this way, we compute the Hodge numbers for all discrete quotients obtained in Braun’s classification http://dx.doi.org/10.1007/JHEP04(2011)005.

  3. Fibonacci and Lucas numbers with applications

    CERN Document Server

    Koshy, Thomas

    2011-01-01

    [Koshy's] book is without doubt the most comprehensive and scholarly work on Fibonacci numbers to date and I am sure that it will quickly signal its presence and impose itself as an authoritative reference manual on Fibonacci numbers. -Napoleon Gauthier, Royal Military College of Canada, Kingston, ON What a gem this is! [...] My only regrest about the book is that it wasn't around years ago. It fills such a void. -Monte Zerger, Adams State College, Alamosa, CO

  4. Random Number Generation for High Performance Computing

    Science.gov (United States)

    2015-01-01

    Memory (DRAM), Double Data Rate Random Access Memory ( DDR RAM ), Static Random Access Memory (SRAM), Extended Data Out Random Access 45 Memory (EDO RAM ...Random Access Memory ( DDR RAM ), Static Random Access Memory (SRAM), Extended Data Out Random Access Memory (EDO RAM ), Rambus Random Access 20 Memory...FTE Equivalent: Total Number: PERCENT_SUPPORTEDNAME FTE Equivalent: Total Number: National Academy Member Rajendra V. Boppana 0.30 Ram C. Tripathi 0.08

  5. Some inequalities for the Bell numbers

    Indian Academy of Sciences (India)

    Feng Qi

    2017-08-19

    Aug 19, 2017 ... 428–431; available online at doi:10.1016/0022-247X(84)90006-4. [16] Qi F, An explicit formula for the Bell numbers in terms of the Lah and Stirling numbers, Mediterr. J. Math. 13(5) (2016) 2795–2800; available online at doi:10.1007/ · s00009-015-0655-7. [17] Qi F, Generalized weighted mean values with ...

  6. Number Albedo of Low-Energy Photons

    International Nuclear Information System (INIS)

    Ljubenov, V.; Simovic, R.; Markovic, S.

    2007-01-01

    Number albedo of water, aluminum and iron for incident photons in energy range from 20 keV to 100 keV is presented in this paper. Results are obtained through the Monte Carlo simulations of photon reflection by using the MCNP, FOTELP and PENELOPE computer codes. Calculated values are compared with the classical data published by B. P. Bulatov and his collaborators. Influence of the fluorescence yield to the photon number albedo of iron target is analyzed in detail. (author)

  7. Bethe's quantum numbers and rigged configurations

    Directory of Open Access Journals (Sweden)

    Anatol N. Kirillov

    2016-04-01

    Full Text Available We propose a method to determine the quantum numbers, which we call the rigged configurations, for the solutions to the Bethe ansatz equations for the spin-1/2 isotropic Heisenberg model under the periodic boundary condition. Our method is based on the observation that the sums of Bethe's quantum numbers within each string behave particularly nicely. We confirm our procedure for all solutions for length 12 chain (totally 923 solutions.

  8. On Fibonacci Numbers Which Are Elliptic Carmichael

    Science.gov (United States)

    2014-12-27

    On Fibonacci numbers which are elliptic Carmichael Florian Luca School of Mathematics University of the Witwatersrand P. O. Box Wits 2050, South...CM elliptic curve with CM field different from Q( √ −1), then the set of n for which the nth Fibonacci number Fn is elliptic Carmichael for E is of...Reports, 1215 Jefferson Davis Highway, Suite 1204, Arlington VA 22202-4302. Respondents should be aware that notwithstanding any other provision of law

  9. Hodge numbers for all CICY quotients

    International Nuclear Information System (INIS)

    Constantin, Andrei; Gray, James; Lukas, Andre

    2017-01-01

    We present a general method for computing Hodge numbers for Calabi-Yau manifolds realised as discrete quotients of complete intersections in products of projective spaces. The method relies on the computation of equivariant cohomologies and is illustrated for several explicit examples. In this way, we compute the Hodge numbers for all discrete quotients obtained in Braun’s classification http://dx.doi.org/10.1007/JHEP04(2011)005.

  10. All-optical fast random number generator.

    Science.gov (United States)

    Li, Pu; Wang, Yun-Cai; Zhang, Jian-Zhong

    2010-09-13

    We propose a scheme of all-optical random number generator (RNG), which consists of an ultra-wide bandwidth (UWB) chaotic laser, an all-optical sampler and an all-optical comparator. Free from the electric-device bandwidth, it can generate 10Gbit/s random numbers in our simulation. The high-speed bit sequences can pass standard statistical tests for randomness after all-optical exclusive-or (XOR) operation.

  11. Large number discrimination in newborn fish.

    Directory of Open Access Journals (Sweden)

    Laura Piffer

    Full Text Available Quantitative abilities have been reported in a wide range of species, including fish. Recent studies have shown that adult guppies (Poecilia reticulata can spontaneously select the larger number of conspecifics. In particular the evidence collected in literature suggest the existence of two distinct systems of number representation: a precise system up to 4 units, and an approximate system for larger numbers. Spontaneous numerical abilities, however, seem to be limited to 4 units at birth and it is currently unclear whether or not the large number system is absent during the first days of life. In the present study, we investigated whether newborn guppies can be trained to discriminate between large quantities. Subjects were required to discriminate between groups of dots with a 0.50 ratio (e.g., 7 vs. 14 in order to obtain a food reward. To dissociate the roles of number and continuous quantities that co-vary with numerical information (such as cumulative surface area, space and density, three different experiments were set up: in Exp. 1 number and continuous quantities were simultaneously available. In Exp. 2 we controlled for continuous quantities and only numerical information was available; in Exp. 3 numerical information was made irrelevant and only continuous quantities were available. Subjects successfully solved the tasks in Exp. 1 and 2, providing the first evidence of large number discrimination in newborn fish. No discrimination was found in experiment 3, meaning that number acuity is better than spatial acuity. A comparison with the onset of numerical abilities observed in shoal-choice tests suggests that training procedures can promote the development of numerical abilities in guppies.

  12. Persistent consequences of atypical early number concepts

    Directory of Open Access Journals (Sweden)

    Michèle M. M. Mazzocco

    2013-09-01

    Full Text Available How does symbolic number knowledge performance help identify young children at risk for poor mathematics achievement outcomes? In research and practice, classification of mathematics learning disability (MLD, or dyscalculia is typically based on composite scores from broad measures of mathematics achievement. These scores do predict later math achievement levels, but do not specify the nature of math difficulties likely to emerge among students at greatest risk for long-term mathematics failure. Here we report that gaps in 2nd and 3rd graders’ number knowledge predict specific types of errors made on math assessments at Grade 8. Specifically, we show that early whole number misconceptions predict slower and less accurate performance, and atypical computational errors, on Grade 8 arithmetic tests. We demonstrate that basic number misconceptions can be detected by idiosyncratic responses to number knowledge items, and that when such misconceptions are evident during primary school they persist throughout the school age years, with variable manifestation throughout development. We conclude that including specific qualitative assessments of symbolic number knowledge in primary school may provide greater specificity of the types of difficulties likely to emerge among students at risk for poor mathematics outcomes.

  13. Complex architecture of primes and natural numbers.

    Science.gov (United States)

    García-Pérez, Guillermo; Serrano, M Ángeles; Boguñá, Marián

    2014-08-01

    Natural numbers can be divided in two nonoverlapping infinite sets, primes and composites, with composites factorizing into primes. Despite their apparent simplicity, the elucidation of the architecture of natural numbers with primes as building blocks remains elusive. Here, we propose a new approach to decoding the architecture of natural numbers based on complex networks and stochastic processes theory. We introduce a parameter-free non-Markovian dynamical model that naturally generates random primes and their relation with composite numbers with remarkable accuracy. Our model satisfies the prime number theorem as an emerging property and a refined version of Cramér's conjecture about the statistics of gaps between consecutive primes that seems closer to reality than the original Cramér's version. Regarding composites, the model helps us to derive the prime factors counting function, giving the probability of distinct prime factors for any integer. Probabilistic models like ours can help to get deeper insights about primes and the complex architecture of natural numbers.

  14. Number skills are maintained in healthy ageing.

    Science.gov (United States)

    Cappelletti, Marinella; Didino, Daniele; Stoianov, Ivilin; Zorzi, Marco

    2014-03-01

    Numerical skills have been extensively studied in terms of their development and pathological decline, but whether they change in healthy ageing is not well known. Longer exposure to numbers and quantity-related problems may progressively refine numerical skills, similar to what happens to other cognitive abilities like verbal memory. Alternatively, number skills may be sensitive to ageing, reflecting either a decline of number processing itself or of more auxiliary cognitive abilities that are involved in number tasks. To distinguish between these possibilities we tested 30 older and 30 younger participants on an established numerosity discrimination task requiring to judge which of two sets of items is more numerous, and on arithmetical tasks. Older participants were remarkably accurate in performing arithmetical tasks although their numerosity discrimination (also known as 'number acuity') was impaired. Further analyses indicate that this impairment was limited to numerosity trials requiring inhibiting information incongruent to numerosity (e.g., fewer but larger items), and that this also correlated with poor inhibitory processes measured by standard tests. Therefore, rather than a numerical impairment, poor numerosity discrimination is likely to reflect elderly's impoverished inhibitory processes. This conclusion is supported by simulations with a recent neuro-computational model of numerosity perception, where only the specific degradation of inhibitory processes produced a pattern that closely resembled older participants' performance. Numeracy seems therefore resilient to ageing but it is influenced by the decline of inhibitory processes supporting number performance, consistent with the 'Inhibitory Deficit' Theory. Copyright © 2013 Elsevier Inc. All rights reserved.

  15. The deep history of the number words.

    Science.gov (United States)

    Pagel, Mark; Meade, Andrew

    2017-02-19

    We have previously shown that the 'low limit' number words (from one to five) have exceptionally slow rates of lexical replacement when measured across the Indo-European (IE) languages. Here, we replicate this finding within the Bantu and Austronesian language families, and with new data for the IE languages. Number words can remain stable for 10 000 to over 100 000 years, or around 3.5-20 times longer than average rates of lexical replacement among the Swadesh list of 'fundamental vocabulary' items. Ordinal evidence suggests that number words also have slow rates of lexical replacement in the Pama-Nyungan language family of Australia. We offer three hypotheses to explain these slow rates of replacement: (i) that the abstract linguistic-symbolic processing of 'number' links to evolutionarily conserved brain regions associated with numerosity; (ii) that number words are unambiguous and therefore have lower 'mutation rates'; and (iii) that the number words occupy a region of the phonetic space that is relatively full and therefore resist change because alternatives are unlikely to be as 'good' as the original word.This article is part of a discussion meeting issue 'The origins of numerical abilities'. © 2017 The Author(s).

  16. A new pseudorandom number generator based on a complex number chaotic equation

    International Nuclear Information System (INIS)

    Liu Yang; Tong Xiao-Jun

    2012-01-01

    In recent years, various chaotic equation based pseudorandom number generators have been proposed. However, the chaotic equations are all defined in the real number field. In this paper, an equation is proposed and proved to be chaotic in the imaginary axis. And a pseudorandom number generator is constructed based on the chaotic equation. The alteration of the definitional domain of the chaotic equation from the real number field to the complex one provides a new approach to the construction of chaotic equations, and a new method to generate pseudorandom number sequences accordingly. Both theoretical analysis and experimental results show that the sequences generated by the proposed pseudorandom number generator possess many good properties

  17. Approximate particle number projection in hot nuclei

    International Nuclear Information System (INIS)

    Kosov, D.S.; Vdovin, A.I.

    1995-01-01

    Heated finite systems like, e.g., hot atomic nuclei have to be described by the canonical partition function. But this is a quite difficult technical problem and, as a rule, the grand canonical partition function is used in the studies. As a result, some shortcomings of the theoretical description appear because of the thermal fluctuations of the number of particles. Moreover, in nuclei with pairing correlations the quantum number fluctuations are introduced by some approximate methods (e.g., by the standard BCS method). The exact particle number projection is very cumbersome and an approximate number projection method for T ≠ 0 basing on the formalism of thermo field dynamics is proposed. The idea of the Lipkin-Nogami method to perform any operator as a series in the number operator powers is used. The system of equations for the coefficients of this expansion is written and the solution of the system in the next approximation after the BCS one is obtained. The method which is of the 'projection after variation' type is applied to a degenerate single j-shell model. 14 refs., 1 tab

  18. True random numbers from amplified quantum vacuum.

    Science.gov (United States)

    Jofre, M; Curty, M; Steinlechner, F; Anzolin, G; Torres, J P; Mitchell, M W; Pruneri, V

    2011-10-10

    Random numbers are essential for applications ranging from secure communications to numerical simulation and quantitative finance. Algorithms can rapidly produce pseudo-random outcomes, series of numbers that mimic most properties of true random numbers while quantum random number generators (QRNGs) exploit intrinsic quantum randomness to produce true random numbers. Single-photon QRNGs are conceptually simple but produce few random bits per detection. In contrast, vacuum fluctuations are a vast resource for QRNGs: they are broad-band and thus can encode many random bits per second. Direct recording of vacuum fluctuations is possible, but requires shot-noise-limited detectors, at the cost of bandwidth. We demonstrate efficient conversion of vacuum fluctuations to true random bits using optical amplification of vacuum and interferometry. Using commercially-available optical components we demonstrate a QRNG at a bit rate of 1.11 Gbps. The proposed scheme has the potential to be extended to 10 Gbps and even up to 100 Gbps by taking advantage of high speed modulation sources and detectors for optical fiber telecommunication devices.

  19. Unpredictability and the transmission of numbers

    Science.gov (United States)

    Myers, John M.; Madjid, F. Hadi

    2016-03-01

    Curiously overlooked in physics is its dependence on the transmission of numbers. For example, the transmission of numerical clock readings is implicit in the concept of a coordinate system. The transmission of numbers and other logical distinctions is often achieved over a computer-mediated communications network in the face of an unpredictable environment. By unpredictable we mean something stronger than the spread of probabilities over given possible outcomes, namely an opening to unforeseeable possibilities. Unpredictability, until now overlooked in theoretical physics, makes the transmission of numbers interesting. Based on recent proofs within quantum theory that provide a theoretical foundation to unpredictability, here we show how regularities in physics rest on a background of channels over which numbers are transmitted. As is known to engineers of digital communications, numerical transmissions depend on coordination reminiscent of the cycle of throwing and catching by players tossing a ball back and forth. In digital communications, the players are computers, and the required coordination involves unpredictably adjusting "live clocks" that step these computers through phases of a cycle. We show how this phasing, which we call logical synchronization, constrains number-carrying networks, and, if a spacetime manifold in invoked, put "stripes" on spacetime. Via its logically synchronized channels, a network of live clocks serves as a reference against which to locate events. Such a network in any case underpins a coordinate frame, and in some cases the direct use of a network can be tailored to investigate an unpredictable environment. Examples include explorations of gravitational variations near Earth.

  20. Robot technology and numbers in the classroom

    DEFF Research Database (Denmark)

    Majgaard, Gunver; Nielsen, Jacob; Misfeldt, Morten

    2010-01-01

    This paper explores how a cubic user-configurable modular robotic system can be used to support learning about numbers and how they are pronounced. The development is done in collaboration with a class of 7-8 year old children and their mathematics teacher. The tool is called Speakmath and it com......This paper explores how a cubic user-configurable modular robotic system can be used to support learning about numbers and how they are pronounced. The development is done in collaboration with a class of 7-8 year old children and their mathematics teacher. The tool is called Speakmath...... and it combines physical interaction, learning, and immediate feedback. Speakmath supports the children’s understanding of place value in the sense that it allows them to experiment and create large numbers. Surprisingly the children found it very fun to express very large numbers, and also made smalls contests...... about who could build the largest number. This made a close tie between learning goals, game play, and the core of Speakmath....