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Sample records for nuclear medicine application

  1. Nuclear Medicine and Application of Nuclear Techniques in Medicine

    International Nuclear Information System (INIS)

    Wiharto, Kunto

    1996-01-01

    The use of nuclear techniques medicine covers not only nuclear medicine and radiology in strict sense but also determination of body mineral content by neutron activation analysis and x-ray fluorescence technique either in vitro or in vivo, application of radioisotopes as tracers in pharmacology and biochemistry, etc. This paper describes the ideal tracer in nuclear medicine, functional and morphological imaging, clinical aspect and radiation protection in nuclear medicine. Nuclear technique offers facilities and chances related to research activities and services in medicine. The development of diagnostic as well as therapeutic methods using monoclonal antibodies labeled with radioisotope will undoubtedly play an important role in the disease control

  2. Computer applications in nuclear medicine

    International Nuclear Information System (INIS)

    Lancaster, J.L.; Lasher, J.C.; Blumhardt, R.

    1987-01-01

    Digital computers were introduced to nuclear medicine research as an imaging modality in the mid-1960s. Widespread use of imaging computers (scintigraphic computers) was not seen in nuclear medicine clinics until the mid-1970s. For the user, the ability to acquire scintigraphic images into the computer for quantitative purposes, with accurate selection of regions of interest (ROIs), promised almost endless computational capabilities. Investigators quickly developed many new methods for quantitating the distribution patterns of radiopharmaceuticals within the body both spatially and temporally. The computer was used to acquire data on practically every organ that could be imaged by means of gamma cameras or rectilinear scanners. Methods of image processing borrowed from other disciplines were applied to scintigraphic computer images in an attempt to improve image quality. Image processing in nuclear medicine has evolved into a relatively extensive set of tasks that can be called on by the user to provide additional clinical information rather than to improve image quality. Digital computers are utilized in nuclear medicine departments for nonimaging applications also, Patient scheduling, archiving, radiopharmaceutical inventory, radioimmunoassay (RIA), and health physics are just a few of the areas in which the digital computer has proven helpful. The computer is useful in any area in which a large quantity of data needs to be accurately managed, especially over a long period of time

  3. The applications of nanomaterials in nuclear medicine

    International Nuclear Information System (INIS)

    Liu Jinjian; Liu Jianfeng

    2010-01-01

    Over the last decade, nanotechnology and nanomaterials have gained rapid development in medical application, especially in targeted drug delivery and gene transfer vector domain, and nano-materials are also beginning to applied in nuclear medicine. This paper is to make a view of the application research of several types of nanomaterials in nuclear medicine, and discuss some problems and the main direction of future development. (authors)

  4. Pulmonary applications of nuclear medicine

    International Nuclear Information System (INIS)

    Kramer, E.L.; Divgi, C.R.

    1991-01-01

    Nuclear medicine techniques have a long history in pulmonary medicine, one that has been continually changing and growing. Even longstanding methods, such as perfusion scanning for embolic disease or for pretherapy pulmonary function evaluation, have largely withstood the test of recent careful scrutiny. Not only have these techniques remained an important part of the diagnostic armamentarium, but we have learned how to use them more effectively. Furthermore, because of technical advances, we are in a phase of expanding roles for nuclear imaging. Gallium citrate scanning for the mediastinal staging and follow-up of lymphoma has been recognized as a valuable adjunct to the anatomic information provided by CT and MRI. With the growth of PET technology in areas that have been explored in a limited fashion until now, such as noncardiogenic pulmonary edema and lung carcinoma, evaluation and management of these patients may substantially improve. Finally, in the field of radiolabeled monoclonal antibodies, attention is now being turned to both the diagnostic and the therapeutic problems presented by lung carcinoma. As radiolabeling methods are refined and as new and better antibodies are developed, radioimmunodetection and therapy in lung carcinoma may begin to make inroads on this common and hard to control disease.157 references

  5. Nuclear medicine applications in AIDS

    International Nuclear Information System (INIS)

    Abdel-Dayem, H.M.

    2004-01-01

    Full text: Aids patients are liable to more than one medical problem at anyone time as the number of CD4 cells decrease and the viral load increases. Problems are related to multiple causes of opportunistic Infections, malignant lymphoma and Kaposi sarcoma. Laboratory tests, sputum analysis and bronchial lavage have problems of decreased sensitivity. morphologic Imaging modalities such as chest X-ray, CT or MRI has problems of specificity. Nuclear medicine techniques has the advantage of total body functional imaging that can visualize more than one organ. The use nuclear medicine imaging is recommended when the diagnosis is uncertain and for initiation of proper treatment. Gallium-67 citrate total body scans acquired at 4 hours following the IV injection and at 24-48 hours has been very useful for the early diagnosis of opportunistic infections such as PCP, TB, Disseminated Mycobacterium avii complex; MAI, malignant lymphoma and various forms of AIDS related colitis. Sequential thallium and gallium scan help to differentiate Kaposi sarcoma (thallium positive, gallium negative) from opportunistic infections (gallium positive, thallium negative) and malignant lymphoma (thallium and gallium positive). Gallium is the most convenient radiopharmaceutical for the diagnosis of malignant lymphoma of the heart. Thallium and Tc-99m Sestamibi are useful for the differentiation of intracranial toxoplasmosis from malignant lymphoma. The presentation will illustrate different examples and will explain the limitations of all these tests. (author)

  6. Nuclear magnetic resonance and medicine. Present applications

    International Nuclear Information System (INIS)

    1984-01-01

    At the workshop on nuclear magnetic resonance and medicine held at Saclay, the following topics were presented: physical principles of NMR; NMR spectroscopy signal to noise ratio; principles of NMR imaging; methods of NMR imaging; image options in NMR; biological significance of contrast in proton NMR imaging; measurement and significance of relaxation times in cancers; NMR contrast agents; NMR for in-vivo biochemistry; potential effects and hazards of NMR applications in Medicine; difficulties of NMR implantation in Hospitals; NMR imaging of brain tumors and diseases of the spinal cord; NMR and Nuclear Medicine in brain diseases [fr

  7. Radiochemistry and its application to nuclear medicine

    International Nuclear Information System (INIS)

    Welch, J.J.

    1990-01-01

    The role of the radiochemist in Nuclear Medicine has increased since the early 1960's. At that time the first medical 99 Mo/ 99m /Tc generator was developed at Brookhaven National Laboratory and the first hospital based cyclotron installed at Washington University. Radiochemists have been involved in both the development and application of generator and accelerator based radiopharmaceuticals. The development of oxygen-15, nitrogen 13, carbon-11 and fluorine-18 simple compound and synthetic precursors will be discussed. In recent years new high current accelerators have been proposed from Nuclear Medicine isotope production. Generator produced radiopharmaceuticals continue to play a major role in Nuclear Medicine. Problems in the development of targetry to produce parent nuclides as well as challenges in generator development will be described

  8. Nuclear medicine applications for the diabetic foot

    International Nuclear Information System (INIS)

    Hartshorne, M.F.; Peters, V.

    1987-01-01

    Although not frequently described in the podiatric literature, nuclear medicine imaging may be of great assistance to the clinical podiatrist. This report reviews in detail the use of modern nuclear medicine approaches to the diagnosis and management of the diabetic foot. Nuclear medicine techniques are helpful in evaluating possible osteomyelitis, in determining appropriate amputation levels, and in predicting response to conservative ulcer management. Specific indications for bone, gallium, and perfusion imaging are described

  9. Nanotechnology and nuclear medicine; research and preclinical applications.

    Science.gov (United States)

    Assadi, Majid; Afrasiabi, Kolsoom; Nabipour, Iraj; Seyedabadi, Mohammad

    2011-01-01

    The birth of nanotechnology in human society was around 2000 years ago and soon found applications in various fields. In this article, we highlight the current status of research and preclinical applications and also future prospects of nanotechnology in medicine and in nuclear medicine. The most important field is cancer. A regular nanotechnology training program for nuclear medicine physicians may be welcome.

  10. Nuclear medicine applications: Summary of Panel 4

    International Nuclear Information System (INIS)

    Wolf, A.P.

    1988-01-01

    Nuclear medicine is currently facing a desperate shortage of organic and inorganic chemists and nuclear pharmacists who also have advanced training in nuclear and radiochemistry. Ironically, this shortfall is occurring in the face of rapid growth and technological advances which have made the practice of nuclear medicine an integral part of the modern health care system. This shortage threatens to limit the availability of radiopharmaceuticals required in routine hospital procedures and to impede the development of new diagnostic and therapeutic agents. To redress this need and prevent a similar shortfall in the future, this panel recommends immediate action and a long-term commitment to the following: educating the public on the benefits of nuclear medicine; informing undergraduate and graduate chemistry students about career opportunities in nuclear medicine; offering upper level courses in nuclear and radiochemistry (including laboratory) in universities; establishing training centers and fellowships at the postgraduate level for specialized education in the aspects of nuclear and radiochemistry required by the nuclear medicine profession. 1 tab

  11. Nuclear Medicine

    Science.gov (United States)

    ... Parents/Teachers Resource Links for Students Glossary Nuclear Medicine What is nuclear medicine? What are radioactive tracers? ... funded researchers advancing nuclear medicine? What is nuclear medicine? Nuclear medicine is a medical specialty that uses ...

  12. The applications of nuclear techniques in nuclear medicine

    International Nuclear Information System (INIS)

    Zhao Huiyang

    1986-01-01

    There are a great deal of advanced techniques in nuclear medicine imaging, because many recent achivements of nuclear techniques have been applied to medicine in recent years. This paper presents the effects of nuclear techniques in development of nuclear medicine imaging. The first part describes radiopharmaceuticals and nuclear medicine imaging including commonly used 99m Tc labeled agents and cyclotron produced radionuclides for organ imaging. The second part describes nuclear medicine instrucments, including PECT, SPECT, MRI ect.; and discussions on the advantages, disadvantages and present status

  13. The application of nuclear-medicine methods in veterinary medicine

    International Nuclear Information System (INIS)

    Simpraga, M.; Kraljevic, P.; Dodig, D.

    1996-01-01

    X-radiography and ultrasound imaging are well established and widely used in veterinary practice, but it is not the same situation with radioisotope imaging. In veterinary practice the above mentioned methods of nuclear medicine are developed only in two countries in Europe. That is not doubt due, so bar, to the difficulties in obtaining satisfactory supply of radioisotopes and to the relatively high cost of scanning equipment. However, in collaboration with the Department of Radiation Protection and Nuclear Medicine of the Medical Faculty in Zagreb, Croatia, we have chance to develop the use of those methods in clinical veterinary practice in Zagreb. That is way in this paper an overview of the application of radioisotopes imaging in veterinary medicine is given. In small animals skeletal changes, lung perusions, brain lesions, space occupying lesions in the liver and its function and hearth function can be usefully searched by a gamma camera and its associated computer. In equine practice scintigraphy of bones, liver, hearth, pulmonary circulation and ventilation is described. The largest amount of radioactive material is used during gamma camera scanning of the skeletons of horses. In this cases the radiation dose 1-2 m from the animal is approximately 3 μSv/h. That is why the protection of personal involved in radioisotope scanning in veterinary medicine must be also regulated by low of radiation protection. Also, the animals should be confined to a controlled area for 2-3 days after scanning before being returned to their owners. After this period the area must be cleaned. (author)

  14. Nuclear medicine

    International Nuclear Information System (INIS)

    Anon.

    1993-01-01

    The area of nuclear medicine, the development of artificially produced radioactive isotopes for medical applications, is relatively recent. Among the subjects covered in a lengthy discussion are the following: history of development; impact of nuclear medicine; understanding the most effective use of radioisotopes; most significant uses of nuclear medicine radioimmunoassays; description of equipment designed for use in the field of nuclear medicine (counters, scanning system, display systems, gamma camera); description of radioisotopes used and their purposes; quality control. Numerous historical photographs are included. 52 refs

  15. Application of nuclear irradiation to traditional chinese medicine

    International Nuclear Information System (INIS)

    Liang Jianping; Li Xuehu; Lu Xihong; Tao Lei; Wang Shuyang

    2010-01-01

    The application of nuclear irradiation in the field of traditional Chinese medicine has received much attention. In this paper we reviewed the application of nuclear radiation on the cultivation, breeding and disinfection of traditional Chinese medicine, and pointed out that the combination of radiation-induced mutagenesis and biological technology would promise broad prospects for increasing the cellular mutation rate and speeding up the genetic improvement of traditional Chinese medicine. (authors)

  16. Nuclear medicine and related radionuclide applications in developing countries

    International Nuclear Information System (INIS)

    1986-01-01

    The Symposium presentations were divided into sessions devoted to the following topics: Radioimmunoassay and related techniques (4 papers and 4 poster presentations); Radionuclide applications in the diagnosis of parasitic diseases (7 papers and 2 posters); Instrumentation (6 papers and 4 posters); Clinical nuclear medicine: liver, bones, thyroid, cardiovascular system, lungs, kidneys, brain (23 papers and 15 posters); Organization of nuclear medicine services in the developing countries (9 papers and 5 posters); Training in nuclear medicine (4 papers) and the panel discussion. Future of Nuclear Medicine in the developing countries. A separate abstract was prepared for each of these papers and posters

  17. Nuclear medicine

    International Nuclear Information System (INIS)

    Blanquet, Paul; Blanc, Daniel.

    1976-01-01

    The applications of radioisotopes in medical diagnostics are briefly reviewed. Each organ system is considered and the Nuclear medicine procedures pertinent to that system are discussed. This includes, the principle of the test, the detector and the radiopharmaceutical used, the procedure followed and the clinical results obtained. The various types of radiation detectors presently employed in Nuclear Medicine are surveyed, including scanners, gamma cameras, positron cameras and procedures for obtaining tomographic presentation of radionuclide distributions [fr

  18. Nuclear medicine

    International Nuclear Information System (INIS)

    Chamberlain, M.J.

    1986-01-01

    Despite an aggressive, competitive diagnostic radiology department, the University Hospital, London, Ontario has seen a decline of 11% total (in vivo and in the laboratory) in the nuclear medicine workload between 1982 and 1985. The decline of in vivo work alone was 24%. This trend has already been noted in the U.S.. Nuclear medicine is no longer 'a large volume prosperous specialty of wide diagnostic application'

  19. Nuclear medicine

    International Nuclear Information System (INIS)

    Lentle, B.C.

    1986-01-01

    Several growth areas for nuclear medicine were defined. Among them were: cardiac nuclear medicine, neuro-psychiatric nuclear medicine, and cancer diagnosis through direct tumor imaging. A powerful new tool, Positron Emission Tomography (PET) was lauded as the impetus for new developments in nuclear medicine. The political environment (funding, degree of autonomy) was discussed, as were the economic and scientific environments

  20. Research advancements and applications of carboranes in nuclear medicinal chemistry

    International Nuclear Information System (INIS)

    Chen Wen; Wei Hongyuan; Luo Shunzhong

    2011-01-01

    Because of their uniquely high thermal and chemical stabilities, carboranes have become a subject of study with high interest in the chemistry of supra molecules, catalysts and radiopharmaceuticals. In recent years, the role of carboranes in nuclear medicinal chemistry has been diversified, from the traditional use in boron neutron capture therapy (BNCT), to the clinical applications in molecular radio imaging and therapy. This paper provides an overview of the synthesis and characterization of carboranes and their applications in nuclear medicinal chemistry, with highlights of recent key advancements in the re- search areas of BNCT and radio imaging. (authors)

  1. Therapeutic Applications of Monte Carlo Calculations in Nuclear Medicine

    CERN Document Server

    Sgouros, George

    2003-01-01

    This book examines the applications of Monte Carlo (MC) calculations in therapeutic nuclear medicine, from basic principles to computer implementations of software packages and their applications in radiation dosimetry and treatment planning. It is written for nuclear medicine physicists and physicians as well as radiation oncologists, and can serve as a supplementary text for medical imaging, radiation dosimetry and nuclear engineering graduate courses in science, medical and engineering faculties. With chapters is written by recognised authorities in that particular field, the book covers the entire range of MC applications in therapeutic medical and health physics, from its use in imaging prior to therapy to dose distribution modelling targeted radiotherapy. The contributions discuss the fundamental concepts of radiation dosimetry, radiobiological aspects of targeted radionuclide therapy and the various components and steps required for implementing a dose calculation and treatment planning methodology in ...

  2. Practical clinical applications of the computer in nuclear medicine

    International Nuclear Information System (INIS)

    Price, R.R.; Erickson, J.J.; Patton, J.A.; Jones, J.P.; Lagan, J.E.; Rollo, F.D.

    1978-01-01

    The impact of the computer on the practice of nuclear medicine has been felt primarily in the area of rapid dynamic studies. At this time it is difficult to find a clinic which routinely performs computer processing of static images. The general purpose digital computer is a sophisticated and flexible instrument. The number of applications for which one can use the computer to augment data acquisition, analysis, or display is essentially unlimited. In this light, the purpose of this exhibit is not to describe all possible applications of the computer in nuclear medicine but rather to illustrate those applications which have generally been accepted as practical in the routine clinical environment. Specifically, we have chosen examples of computer augmented cardiac, and renal function studies as well as examples of relative organ blood flow studies. In addition, a short description of basic computer components and terminology along with a few examples of non-imaging applications are presented

  3. Recent applications of nuclear medicine in diagnostics (I part

    Directory of Open Access Journals (Sweden)

    Giorgio Treglia

    2013-04-01

    Full Text Available Introduction: Aim of this review is to describe the recent applications of nuclear medicine techniques in diagnostics, particularly in oncology. Materials and methods: We reviewed scientific literature data searching for the current role of tomographic nuclear medicine techniques (SPECTand PET in oncology and summarized the main applications of these techniques. Results: Nuclear medicine techniques have a key role in oncology allowing early diagnosis of many tumours, an accurate staging of disease and evalutation of treatment response. Hybrid SPECT/CT and PET/CT imaging systems now provide metabolic and functional information from SPECTor PETcombined with the high spatial resolution and anatomic information of CT. The most frequent applications of SPECT/CT in oncology concern thyroid tumours, neuroendocrine tumours, bone metastases and lymph node mapping. Furthermore the evaluation of many tumours may benefit from PET/CT imaging. Discussion: The recent development of new radiopharmaceuticals and the growth of hybrid tomographic devices, such as SPECT/CT and PET/CT, now permits molecular imaging of biologic processes at the cellular level to improve both the diagnosis and treatment of many tumours.

  4. The developments and applications of molecular nuclear medicine

    International Nuclear Information System (INIS)

    Fang Shengwei; Xi Wang; Zhang Hong

    2009-01-01

    Molecular nuclear medicine including PET and SPECT is one of the most important parts of the molecular imaging. The combinations of molecular unclear medicine with CT, MRI, ultrasound or optical imaging and synthesis of multimodality radiopharmaceuticals are the major trends of the development of nuclear medicine. Molecular nuclear medicine has more and more and more important value on the monitoring of response to biology involved gene therapy or stem cell therapy and the developments of new drug. (authors)

  5. Clinical nuclear medicine applications in Turkey and specific renal studies

    International Nuclear Information System (INIS)

    Erbas, B.

    2004-01-01

    Full text: Nuclear cardiology, nuclear oncology, pediatric nuclear medicine and nuclear endocrinology are the main application areas of clinical nuclear medicine in Turkey. Not only imaging studies, but also therapeutic application of radiopharmaceuticals is also performed at many institutes, such as hyperthyroidism treatment with radioiodine, thyroid cancer ablation and metastases treatment with radioiodine, radio synovectomy, metastatic pain therapy, and recently radioimmunotherapy of lymphomas. Almost all radionuclides and radiopharmaceuticals are obtained commercially from European countries, except 18-FDG which is obtained from two cyclotrons in Turkey. More than 30.000 renal procedures are performed at the University hospitals in a year. Pediatric age groups is approximately % 55 of patients. 99mTc-DTPA (%44), 99mTc-DMSA (%37), 99mTc-MAG3 (%17) and 99mTc-EC (%2) are the most commonly used radiopharmaceuticals for renal imaging. More than 6.000 vials of several pharmaceuticals are used for renal cortical scintigraphy (%35), dynamic renal imaging (%34), renal scintigraphy with diuretic (%27) and captopril scintigraphy (%4). Most common indication for renal cortical scintigraphy is detection of cortical scarring (%53). In addition, using single plasma sample method or gamma-camera method renal clearance measurements with 99mTc-MAG3 99mTc-DTPA have been used at some institutions

  6. Clinical nuclear medicine applications in Turkey and specific renal studies

    International Nuclear Information System (INIS)

    Erbas, B.

    2004-01-01

    Nuclear cardiology, nuclear oncology, pediatric nuclear medicine and nuclear endocrinology are the main application areas of clinical nuclear medicine in Turkey. Not only imaging studies, but also therapeutic application of radiopharmaceuticals is also performed at many institutes, such as hyperthyroidism treatment with radioiodine, thyroid cancer ablation and metastases treatment with radioiodine, radio synovectomy, metastatic pain therapy, and recently radioimmunotherapy of lymphomas. Almost all radionuclides and radiopharmaceuticals are obtained commercially from European countries, except 18-FDG which is obtained from two cyclotrons in Turkey. More than 30.000 renal procedures are performed at the University hospitals in a year. Pediatric age groups is approximately % 55 of patients. 99m Tc-DTPA (%44), 99m Tc-DMSA (%37), 99m Tc-MAG3 (%17) and 99m Tc-EC (%2) are the most commonly used radiopharmaceuticals for renal imaging. More than 6.000 vials of several pharmaceuticals are used for renal cortical scintigraphy (%35), dynamic renal imaging (%34), renal scintigraphy with diuretic (%27) and captopril scintigraphy (%4). Most common indication for renal cortical scintigraphy is detection of cortical scarring (%53). In addition, using single plasma sample method or gamma-camera method renal clearance measurements with 99m Tc-MAG3 99m Tc-DTPA have been used at some institutions. (author)

  7. Search of new scintillation materials for nuclear medicine application

    CERN Document Server

    Korzhik, M

    2001-01-01

    Oxide crystals have a great potential to develop new advanced scintillation materials which are dense, fast, and bright. This combination of parameters, when combined to affordable price, gives a prospect for materials to be applied in nuclear medicine devices. Some of them have been developed for the last two decades along the line of rear-earth (RE) garnet (RE//3Al//5O//1//2) oxiorthosilicate (RE//2SiO//5) and perovskite (REAlO//3) crystals doped with Ce ions. Among recently developed oxide materials the lead tungstate scintillator (PWO) becomes the most used scintillation materials in high energy physics experiments due to its application in CMS and ALICE experiments at LHC. In this paper we discuss scintillation properties of some new heavy compounds doped with Ce as well as light yield improvement of PWO crystals to apply them in low energy physics and nuclear medicine. 18 Refs.

  8. Applications of slant collimators to cardiovascular nuclear medicine

    International Nuclear Information System (INIS)

    Nishimura, Tsunehiko; Uehara, Toshio; Hayashi, Makoto; Kagawa, Masaaki; Kozuka, Takahiro

    1980-01-01

    The RI examination of hearts is attracting increasingly interest as cardiovascular nuclear medicine in recent years. As for the background, there are the development of such radioactive agents with high heart-muscle specificity as 201 TICI and the minicomputer capability of measuring rapid contraction and expansion of hearts. Under the situation, the variety of contrivance in collimators is attempted for higher accuracy in grasping the form and function of hearts. With a 30 deg inclination slant type collimator (made by EDC firm) which became available, its applications as cardiovascular nuclear medicine have been examined in heart-muscle scintigraphy and heart RI angiography. These results are described. In the above connection, a bifocal collimator and a seven pinhole collimator are also explained briefly. (J.P.N.)

  9. Recent applications of nuclear medicine in diagnostics: II part

    Directory of Open Access Journals (Sweden)

    Giorgio Treglia

    2013-04-01

    Full Text Available Introduction: Positron-emission tomography (PET and single photon emission computed tomography (SPECT are effective diagnostic imaging tools in several clinical settings. The aim of this article (the second of a 2-part series is to examine some of the more recent applications of nuclear medicine imaging techniques, particularly in the fields of neurology, cardiology, and infection/inflammation. Discussion: A review of the literature reveals that in the field of neurology nuclear medicine techniques are most widely used to investigate cognitive deficits and dementia (particularly those associated with Alzheimer disease, epilepsy, and movement disorders. In cardiology, SPECT and PET also play important roles in the work-up of patients with coronary artery disease, providing accurate information on the state of the myocardium (perfusion, metabolism, and innervation. White blood cell scintigraphy and FDG-PET are widely used to investigate many infectious/inflammatory processes. In each of these areas, the review discusses the use of recently developed radiopharmaceuticals, the growth of tomographic nuclear medicine techniques, and the ways in which these advances are improving molecular imaging of biologic processes at the cellular level.

  10. Some Applications of Nuclear Physics in Medicine and Dentistry

    International Nuclear Information System (INIS)

    Anwar Chaudhri, M.; Nasir Chaudhri, M.

    2009-01-01

    Some applications of nuclear physics, to solve problems in dentistry and medicine are presented. The following two topics are going to be discussed: A. Nuclear Analytical Methods For Trace Element Studies In Teeth Various nuclear analytical methods have been developed and applied to determine the elemental composition of teeth. Fluorine was determined by prompt gamma activation analysis through the 19 F (p, a v) 16 O reaction. Carbon was measured by activation analysis with He-3 ions, and the technique of Proton-Induced X-ray Emission (PIXE) was applied to simultaneously determine Ca, P, and trace elements in well-documented teeth. Dental hard tissues: enamel, dentine, cement, and their junctions, as well as different parts of the same tissue, were examined separately.

  11. Nuclear medicine

    International Nuclear Information System (INIS)

    Casier, Ph.; Lepage, B.

    1998-01-01

    Except for dedicated devices for mobile nuclear cardiology for instance, the market is set on variable angulation dual heads cameras. These cameras are suited for all general applications and their cost effectiveness is optimized. Now, all major companies have such a camera in their of products. But, the big question in nuclear medicine is about the future of coincidence imaging for the monitoring of treatments in oncology. Many companies are focused on WIP assessments to find out the right crustal thickness to perform both high energy FDG procedures and low energy Tc procedures, with the same SPECT camera. The classic thickness is 3/8''. Assessments are made with 1/2'', 5/8'' or 3/4'' crystals. If FDG procedures proved to be of great interest in oncology, it may lead to the design of a dedicated SPECT camera with a 1'' crustal. Due to the short half of FDG, it may be the dawning of slip ring technology. (e.g. Varicam from Elscint). The three small heads camera market seems to be depressed. Will the new three large heads camera unveiled by Picker, reverse that trend? The last important topic in nuclear medicine is the emergence of new flat digital detectors to get rid of the old bulky ones. Digirad is the first company to manufacture a commercial product based on that technology. Bichron, Siemens and General Electric are working on that development, too. But that technology is very expensive and the market for digital detection in nuclear medicine is not as large as the market in digital detection in radiology. (author)

  12. Nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Sharma, S M [Bhabha Atomic Research Centre, Bombay (India). Radiation Medicine Centre

    1967-01-01

    The article deals with the growth of nuclear medicine in India. Radiopharmaceuticals both in elemental form and radiolabelled compounds became commercially available in India in 1961. Objectives and educational efforts of the Radiation Medicine Centre setup in Bombay are mentioned. In vivo tests of nuclear medicine such as imaging procedures, dynamic studies, dilution studies, thyroid function studies, renal function studies, linear function studies, blood flow, and absorption studies are reported. Techniques of radioimmunoassay are also mentioned.

  13. Nuclear medicine

    International Nuclear Information System (INIS)

    Kand, Purushottam

    2012-01-01

    Nuclear medicine is a specialized area of radiology that uses very small amounts of radioactive materials to examine organ function and structure. Nuclear medicine is older than CT, ultrasound and MRI. It was first used in patients over 60-70 years ago. Today it is an established medical specialty and offers procedures that are essential in many medical specialities like nephrology, pediatrics, cardiology, psychiatry, endocrinology and oncology. Nuclear medicine refers to medicine (a pharmaceutical) that is attached to a small quantity of radioactive material (a radioisotope). This combination is called a radiopharmaceutical. There are many radiopharmaceuticals like DTPA, DMSA, HIDA, MIBI and MDP available to study different parts of the body like kidneys, heart and bones etc. Nuclear medicine uses radiation coming from inside a patient's body where as conventional radiology exposes patients to radiation from outside the body. Thus nuclear imaging study is a physiological imaging, whereas diagnostic radiology is anatomical imaging. It combines many different disciplines like chemistry, physics mathematics, computer technology, and medicine. It helps in diagnosis and to treat abnormalities very early in the progression of a disease. The information provides a quick and accurate diagnosis of wide range of conditions and diseases in a person of any age. These tests are painless and most scans expose patients to only minimal and safe amounts of radiation. The amount of radiation received from a nuclear medicine procedure is comparable to, or often many times less than, that of a diagnostic X-ray. Nuclear medicine provides an effective means of examining whether some tissues/organs are functioning properly. Therapy using nuclear medicine in an effective, safe and relatively inexpensive way of controlling and in some cases eliminating, conditions such as overactive thyroid, thyroid cancer and arthritis. Nuclear medicine imaging is unique because it provides doctors with

  14. Some computer applications and digital image processing in nuclear medicine

    International Nuclear Information System (INIS)

    Lowinger, T.

    1981-01-01

    Methods of digital image processing are applied to problems in nuclear medicine imaging. The symmetry properties of central nervous system lesions are exploited in an attempt to determine the three-dimensional radioisotope density distribution within the lesions. An algorithm developed by astronomers at the end of the 19th century to determine the distribution of matter in globular clusters is applied to tumors. This algorithm permits the emission-computed-tomographic reconstruction of spherical lesions from a single view. The three-dimensional radioisotope distribution derived by the application of the algorithm can be used to characterize the lesions. The applicability to nuclear medicine images of ten edge detection methods in general usage in digital image processing were evaluated. A general model of image formation by scintillation cameras is developed. The model assumes that objects to be imaged are composed of a finite set of points. The validity of the model has been verified by its ability to duplicate experimental results. Practical applications of this work involve quantitative assessment of the distribution of radipharmaceuticals under clinical situations and the study of image processing algorithms

  15. Therapeutic Applications of Monte Carlo Calculations in Nuclear Medicine

    International Nuclear Information System (INIS)

    Coulot, J

    2003-01-01

    Monte Carlo techniques are involved in many applications in medical physics, and the field of nuclear medicine has seen a great development in the past ten years due to their wider use. Thus, it is of great interest to look at the state of the art in this domain, when improving computer performances allow one to obtain improved results in a dramatically reduced time. The goal of this book is to make, in 15 chapters, an exhaustive review of the use of Monte Carlo techniques in nuclear medicine, also giving key features which are not necessary directly related to the Monte Carlo method, but mandatory for its practical application. As the book deals with therapeutic' nuclear medicine, it focuses on internal dosimetry. After a general introduction on Monte Carlo techniques and their applications in nuclear medicine (dosimetry, imaging and radiation protection), the authors give an overview of internal dosimetry methods (formalism, mathematical phantoms, quantities of interest). Then, some of the more widely used Monte Carlo codes are described, as well as some treatment planning softwares. Some original techniques are also mentioned, such as dosimetry for boron neutron capture synovectomy. It is generally well written, clearly presented, and very well documented. Each chapter gives an overview of each subject, and it is up to the reader to investigate it further using the extensive bibliography provided. Each topic is discussed from a practical point of view, which is of great help for non-experienced readers. For instance, the chapter about mathematical aspects of Monte Carlo particle transport is very clear and helps one to apprehend the philosophy of the method, which is often a difficulty with a more theoretical approach. Each chapter is put in the general (clinical) context, and this allows the reader to keep in mind the intrinsic limitation of each technique involved in dosimetry (for instance activity quantitation). Nevertheless, there are some minor remarks to

  16. Nuclear medicine physics

    CERN Document Server

    De Lima, Joao Jose

    2011-01-01

    Edited by a renowned international expert in the field, Nuclear Medicine Physics offers an up-to-date, state-of-the-art account of the physics behind the theoretical foundation and applications of nuclear medicine. It covers important physical aspects of the methods and instruments involved in modern nuclear medicine, along with related biological topics. The book first discusses the physics of and machines for producing radioisotopes suitable for use in conventional nuclear medicine and PET. After focusing on positron physics and the applications of positrons in medicine and biology, it descr

  17. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... Physician Resources Professions Site Index A-Z Children's (Pediatric) Nuclear Medicine Children’s (pediatric) nuclear medicine imaging uses ... limitations of Children's Nuclear Medicine? What is Children's (Pediatric) Nuclear Medicine? Nuclear medicine is a branch of ...

  18. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... Professions Site Index A-Z Children's (Pediatric) Nuclear Medicine Children’s (pediatric) nuclear medicine imaging uses small amounts ... Children's Nuclear Medicine? What is Children's (Pediatric) Nuclear Medicine? Nuclear medicine is a branch of medical imaging ...

  19. General Nuclear Medicine

    Science.gov (United States)

    ... Resources Professions Site Index A-Z General Nuclear Medicine Nuclear medicine imaging uses small amounts of radioactive ... of General Nuclear Medicine? What is General Nuclear Medicine? Nuclear medicine is a branch of medical imaging ...

  20. Children's (Pediatric) Nuclear Medicine

    Science.gov (United States)

    ... Professions Site Index A-Z Children's (Pediatric) Nuclear Medicine Children’s (pediatric) nuclear medicine imaging uses small amounts ... Children's Nuclear Medicine? What is Children's (Pediatric) Nuclear Medicine? Nuclear medicine is a branch of medical imaging ...

  1. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... News Physician Resources Professions Site Index A-Z Children's (Pediatric) Nuclear Medicine Children’s (pediatric) nuclear medicine imaging ... the limitations of Children's Nuclear Medicine? What is Children's (Pediatric) Nuclear Medicine? Nuclear medicine is a branch ...

  2. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... Resources Professions Site Index A-Z Children's (Pediatric) Nuclear Medicine Children’s (pediatric) nuclear medicine imaging uses small ... of Children's Nuclear Medicine? What is Children's (Pediatric) Nuclear Medicine? Nuclear medicine is a branch of medical ...

  3. Medical application of nuclear science: nuclear medicine and production of radiopharmaceuticals

    International Nuclear Information System (INIS)

    Cornet, L.

    1997-01-01

    Nuclear science in attendance on medicine or from Radium to Radiopharmaceuticals. By a brief historical reminder of the evolution of the radioactivity and development of nuclear science, we could see a very early interest and application of the radioactivity in the medical field. Main steps: Detection of natural radioactivity/Discovery of artificial radioactivity/First treatment of leukaemia and thyroid/First nuclear reactor/First radioisotope laboratory in hospital/First scintigraphy/First radiopharmaceutical/First cyclotron and cyclotron products/First immunoscintigraphy/Biotechnology and radioisotope/Evolution of technics [equipment for diagnosis (imaging, scintigraphy) and therapy]/Evolution of production technics and concept of products (generators of Technetium) and machines, reactor, cyclotron/Evolution of importance and interest of nuclear medicine/Creation of international association of nuclear medicine and producers (example ARPR)/Evolution of safety and pharmaceuticals regulation. After the sixties, period extremely rich in invention of products, characterized by a high fertility specially due to a non-restrictive regulation in terms of safety and pharmaceutical consideration, the evolution of technics, the importance of costs (investment, research, healthcare and the evolution of the regulations) have smoothly but continuously transformed the contexts and different actors. Consequences and facts: Rationalization and standardization of the catalogues, total integration of radiopharmaceuticals into the pharmaceutical laws, stop of nuclear research reactors, increase of number of cyclotrons, transformation of size and role of the producers and nuclear centers, risk in supply of some raw materials like Molybdenum, medical nuclear application as a worldwide business

  4. Recent applications of nuclear medicine techniques and results in Vietnam

    International Nuclear Information System (INIS)

    Phan Sy An

    2008-01-01

    The author presented recent applications of nuclear medicine techniques and results in Vietnam. The author concentrated some valuable and helpful studies such as functional tests, myocardial perfusion scintigraphy, bone, thyroid, lung, kidney and gastrointestinal tract scintigraphy for diagnosis. The results of RIA and IRMA concerning with thyroid diseases, cancer, microalbuminuria and TSH in blood spot on paper for screening of congenital hypothyroidism in new born babies were also given. The report also mentioned results of liver cancer and palliative bone metastasis treatments in Vietnam. A new technique using gamma probe in surgery for breast cancer was presented. The author introduced some modern teleradiotherapeutic modalities such as cyberknif, gamma knife, gamma rotating systeme and linac recently installed in Vietnam. (author)

  5. Applications of CdTe to nuclear medicine. Final report

    International Nuclear Information System (INIS)

    Entine, G.

    1985-01-01

    Uses of cadmium telluride (CdTe) nuclear detectors in medicine are briefly described. They include surgical probes and a system for measuring cerebral blood flow in the intensive care unit. Other uses include nuclear dentistry, x-ray exposure control, cardiology, diabetes, and the testing of new pharmaceuticals

  6. Nuclear medicine

    International Nuclear Information System (INIS)

    Reichelt, H.G.

    1980-01-01

    Nuclear medicine as a complex diagnostical method is used mainly to detect functional organic disorders, to locate disorders and for radioimmunologic assays (RIA) in vitro. In surgery, its indication range comprises the thyroid (in vivo and in vitro), liver and bile ducts, skeletal and joint diseases, disorders of the cerebro-spinal liquor system and the urologic disorders. In the early detection of tumors, the search for metastases and tumor after-care, scintiscanning and the tumor marcher method (CEA) can be of great practical advantage, but the value of myocardial sciritiscanning in cardiac respectively coronary disorders is restricted. The paper is also concerned with the radiation doses in nuclear medicine. (orig.) [de

  7. Nuclear energy and medicine

    International Nuclear Information System (INIS)

    1988-01-01

    The applications of nuclear energy on medicine, as well as the basic principles of these applications, are presented. The radiological diagnosis, the radiotherapy, the nuclear medicine, the radiological protection and the production of radioisotopes are studied. (M.A.C.) [pt

  8. Nuclear medicine

    International Nuclear Information System (INIS)

    Sibille, L.; Nalda, E.; Collombier, L.; Kotzki, P.O.; Boudousq, V.

    2011-01-01

    Nuclear medicine is a medical specialty using the properties of radioactivity. Radioactive markers associated with vectors are used as a tracer or radiopharmaceutical for diagnostic purposes and/or therapy. Since its birth more than half a century ago, it has become essential in the care of many patients, particularly in oncology. After some definitions, this paper presents the main nuclear techniques - imaging for diagnostic, radiopharmaceuticals as therapeutic agents, intra-operative detection, technique of radioimmunoassay - and the future of this field. (authors)

  9. Digital Nuclear Medicine

    International Nuclear Information System (INIS)

    Erickson, J.J.; Rollo, F.D.

    1982-01-01

    This book is meant ''to provide the most comprehensive presentation of the technical as well as clincial aspects of computerized nuclear medicine''. It covers basic applications, and advice on acquisition and quality control of nuclear medicine computer systems. The book evolved from a series of lectures given by the contributors during the computer preceptorship program at their institution, Vanderbilt University in Nashville

  10. Development of indigenous technology at CNEN in the fields of nuclear medicine, nuclear detectors, instrumentation, radioisotope production and application of nuclear techniques

    International Nuclear Information System (INIS)

    Mafra, O.

    1990-01-01

    The main objectives of the program developed at CNEN in the field of nuclear medicine, nuclear detectors, instrumentation, radioisotope production and application of nuclear technique are described. (E.G.) [pt

  11. Veterinary nuclear medicine

    International Nuclear Information System (INIS)

    Kallfelz, F.A.; Comar, C.L.; Wentworth, R.A.

    1974-01-01

    A brief review is presented of the expanding horizons of nuclear medicine, the equipment necessary for a nuclear medicine laboratory is listed, and the value of this relatively new field to the veterinary clinician is indicated. Although clinical applications to veterinary medicine have not kept pace with those of human medicine, many advances have been made, particularly in the use of in vitro techniques. Areas for expanded applications should include competitive protein binding and other in vitro procedures, particularly in connection with metabolic profile studies. Indicated also is more intensive application by the veterinarian of imaging procedures, which have been found to be of such great value to the physician. (U.S.)

  12. Nuclear medicine

    International Nuclear Information System (INIS)

    James, A.E. Jr.; Squire, L.F.

    1977-01-01

    The book presents a number of fundamental imaging principles in nuclear medicine. The fact that low radiation doses are sufficient for the study of normal and changed physiological functions of the body is an important advancement brought about by nuclear medicine. The possibility of quantitative investigations of organs and organ regions and of an assessment of their function as compared to normal values is a fascinating new diagnostic dimension. The possibility of comparing the findings with other pathological findings and of course control in the same patient lead to a dynamic continuity with many research possibilities not even recognized until now. The limits of nuclear scanning methods are presented by the imprecise structural information of the images. When scintiscans are compared with X-ray images or contrast angiography, the great difference in the imaging of anatomical details is clearly seen. But although the present pictures are not optimal, they are a great improvement on the pictures that were considered clinically valuable a few years ago. (orig./AJ) [de

  13. Nuclear Medicine in Turkey

    International Nuclear Information System (INIS)

    Durak, H.

    2001-01-01

    Nuclear Medicine is a medical specialty that uses radionuclides for the diagnosis and treatment of diseases and it is one of the most important peaceful applications of nuclear sciences. Nuclear Medicine has a short history both in Turkey and in the world. The first use of I-131 for the treatment of thyrotoxicosis in Turkey was in 1958 at the Istanbul University Cerrahpasa Medical School. In 1962, Radiobiological Institute in Ankara University Medical School was established equipped with well-type counters, radiometers, scalers, external counters and a rectilinear scanner. In 1965, multi-probe external detection systems, color dot scanners and in 1967, anger scintillation camera had arrived. In 1962, wet lab procedures and organ scanning, in 1965 color dot scanning, dynamic studies (blood flow - renograms) and in 1967 analogue scintillation camera and dynamic camera studies have started. In 1974, nuclear medicine was established as independent medical specialty. Nuclear medicine departments have started to get established in 1978. In 1974, The Turkish Society of Nuclear Medicine (TSNM) was established with 10 members. The first president of TSNM was Prof. Dr. Yavuz Renda. Now, in the year 2000, TSNM has 349 members. Turkish Society of Nuclear Medicine is a member of European Association of Nuclear Medicine (EANM), World Federation of Nuclear Medicine and Biology (WFNMB) and WFNMB Asia-Oceania. Since 1974, TSNM has organized 13 national Nuclear Medicine congresses, 4 international Nuclear Oncology congresses and 13 nuclear medicine symposiums. In 1-5 October 2000, 'The VII th Asia and Oceania Congress of Nuclear Medicine and Biology' was held in Istanbul, Turkey. Since 1992, Turkish Journal of Nuclear Medicine is published quarterly and it is the official publication of TSNM. There are a total of 112 Nuclear Medicine centers in Turkey. There are 146 gamma cameras. (52 Siemens, 35 GE, 16 Elscint, 14 Toshiba, 10 Sopha, 12 MIE, 8 Philips, 9 Others) Two cyclotrons are

  14. Metallic radionuclides: applications in diagnostic and therapeutic nuclear medicine

    International Nuclear Information System (INIS)

    Weiner, R.E.; Thakur, M.L.

    1995-01-01

    Nuclear Medicine is a medical modality that utilizes radioactivity (radiopharmaceutical) to diagnose and treat disease. Radiopharmaceuticals contain a component which directs the radionuclide to the desire physiological target. For diagnostic applications, these nuclides must emit a γ ray that can penetrate the body and can be detected externally while for therapeutic purposes nuclides are preferred that emit β particles and deliver highly localized tissue damage. 67 Ga citrate is employed to detect chronic occult abscesses, Hodgkin's and non-Hodgkin's lymphomas, lung cancer, hepatoma and melanoma and localizes in these tissues utilizing iron-binding proteins. 201 Thallous chloride, a potassium analogue, used to diagnosis coronary artery disease, is incorporated in muscle tissue via the Na + -K + -ATPase. 111 In labeled autologous white blood cells, used for the diagnosis of acute infections and inflammations, takes advantage of the white cell's role in fighting infections. 111 In is incorporated in other radiopharmaceuticals e.g. polyclonal IgG, OncoScint CR/OV, OctreoScan and Myoscint by coupling diethylenetriaminepentaacetic acid, a chelate, covalently to these molecules. OncoScint CR/OV and Myoscint localize by antigen-antibody interactions while OctreoScan is taken up by malignant cells in a receptor based process. Polyclonal IgG may share some localization characteristics with 67 Ga. 89 Sr, a pure β emitter, is used for palliation of bone pain due to metastatic bone lesions. Bone salts [Ca(PO) 4 ] are increased in these lesions and this radionuclide is taken up similarly to Ca 2+ . 186 Re and 153 Sm bound to polydentate phosphonate chelates are used similarly and follow the phosphate pathway in lesion incorporation. (orig.)

  15. Metallic radionuclides: Applications in diagnostic and therapeutic nuclear medicine

    International Nuclear Information System (INIS)

    Werner, R.E.; Thakur, M. L.

    1997-01-01

    Nuclear Medicine is a medical modality that utilizes radioactivity (radiopharmaceutical) to diagnose and treat disease. Radiopharmaceuticals contain a component which directs the radionuclide to the desire physiological target. For diagnostic applications, these nuclides must emit a gamma ray that can penetrate the body and can be detected externally while for therapeutic purposes nuclides are preferred that emit beta particles and deliver highly localized tissue damage. sup 6 sup 7 Ga citrate is employed to detect chronic occult abscesses, Hodgkin's and non-Hodgkin's lymphomas, lung cancer, hepatoma and melanoma and localizes in these tissues utilizing iron-binding proteins. sup 2 sup 0 sup 1 Thallous chloride, a potassium analogue, used to diagnosis coronary artery disease, is incorporated in muscle tissue via the Na sup + -K sup + -ATPase. sup 1 sup 1 sup 1 In labeled autologous white blood cells, used for the diagnosis of acute infections and inflammations, takes advantage of the white cell's role in fighting infections. sup 1 sup 1 sup 1 In is incorporated in other radiopharmaceuticals e.g. polyclonal IgG, OncoScint CR/OV, OctreoScan and Myoscint by coupling diethylenetriaminepentaacetic acid, a chelate, covalently to these molecules. OncoScint CR/OV and Myoscint localize by antigen-antibody interactions while OctreoScan is taken up by malignant cells in a receptor based process. Polyclonal IgG may share some localization characteristics with sup 6 sup 7 Ga. sup 8 sup 9 Sr, a pure beta emitter, is used for palliation of bone pain due to metastatic bone lesions. Bone salts [Ca(PO) sub 4] are increased in these lesions and this radionuclide is taken up similarly to Ca sup 2 sup +. sup 1 sup 8 sup 6 Re and sup 1 sup 5 sup 3 Sm bound to polydentate phosphonate chelates are used similarly and follow the phosphate pathway in lesion incorporation. (author)

  16. Application of radioisotopes in the field of nuclear medicine

    International Nuclear Information System (INIS)

    Nayak, D.; Lahiri, S.

    1999-01-01

    A comprehensive review has been made to discuss the role of various radionuclides of lanthanide series elements in the field of nuclear medicine. The role of several pharmaceuticals labeled with radiolanthanides and used for investigative purposes like measurement of cerebral blood flow, bone density measurement, bone marrow imaging, etc., have been described. The role of lanthanide radionuclides in radiation synovectomy, radioimmunotherapy, etc., have also been discussed. Methods of preparation of some representative radiopharmaceuticals like 153 Sm-EDTMP, 153 Sm-HYP, have been presented. An outline on the production of carrier free radioisotopes of lanthanide series elements has been given. (author)

  17. Practical nuclear medicine

    CERN Document Server

    Gemmell, Howard G; Sharp, Peter F

    2006-01-01

    Nuclear medicine plays a crucial role in patient care, and this book is an essential guide for all practitioners to the many techniques that inform clinical management. The first part covers the scientific basis of nuclear medicine, the rest of the book deals with clinical applications. Diagnostic imaging has an increasingly important role in patient management and, despite advances in other modalities (functional MRI and spiral CT), nuclear medicine continues to make its unique contribution by its ability to demonstrate physiological function. This book is also expanded by covering areas of d

  18. Applications of nuclear technology in industry, environment and medicine

    International Nuclear Information System (INIS)

    Vera Ruiz, H.

    1998-01-01

    This article contains information on different applications of nuclear technology, such as: sterilization of single use medical products, radiation serialization of pharmaceutical products,radiation treatment of disposable products, in Europe, radiation treatment of micro-titer plates, several crosslinking processes, radiation vulcanization of natural rubber latex, irradiation of polymers to obtain dressings for burns, ulcers bedsores and skin grafts, production of ground water with accelerated electrons in combination with accelerated electrons in combination with ozone, radiation treatment of hospital wastes. (S. Grainger)

  19. Handbooks in radiology: Nuclear medicine

    International Nuclear Information System (INIS)

    Datz, F.L.

    1988-01-01

    This series of handbooks covers the basic facts, major concepts and highlights in seven radiological subspecialties. ''Nuclear Medicine'' is a review of the principles, procedures and clinical applications that every radiology resident and practicing general radiologist should know about nuclear medicine. Presented in an outline format it covers all of the organ systems that are imaged by nuclear medicine

  20. Application impact of internal monitoring criteria in radiological protection programs of nuclear medicine services

    International Nuclear Information System (INIS)

    Dantas, Bernardo M.; Dantas, Ana Leticia A.; Juliao, Ligia Q.C.; Lourenco, Maria Cristina; Melo, Dunstana R.

    2005-01-01

    This work presents the simulation of the internal monitoring criteria application for the most used radionuclides by the area of nuclear medicine, taking into consideration the usual conditions of usual source handling and the activity bands authorized by the CNEN. It is concluded that the handling of Iodine 131 for therapeutical purposes is the practice which presents the most risk of internal exposure for the works, requiring the adoption of a program for internal monitoring by the nuclear medicine services

  1. Radioisotopes in nuclear medicine

    International Nuclear Information System (INIS)

    Samuel, A.M.

    2002-01-01

    Full text: A number of advances in diverse fields of science and technology and the fruitful synchronization of many a new development to address the issues related to health care in terms of prognosis and diagnosis resulted in the availability of host of modern diagnostic tools in medicine. Nuclear medicine, a unique discipline in medicine is one such development, which during the last four decades has seen exponential growth. The unique contribution of this specialty is the ability to examine the dynamic state of every organ of the body with the help of radioactive tracers. This tracer application in nuclear medicine to monitor the biological molecules that participate in the dynamic state of body constituents has led to a whole new approach to biology and medicine. No other technique has the same level of sensitivity and specificity as obtained in radiotracer technique in the study of in-situ chemistry of body organs. As modem medicine becomes oriented towards molecules rather than organs, nuclear medicine will be in the forefront and will become an integral part of a curative process for regular and routine application. Advances in nuclear medicine will proceed along two principal lines: (i) the development of improved sensitive detectors of radiation, powerful and interpretable data processing, image analysis and display techniques, and (ii) the production of exotic and new but useful radiopharmaceuticals. All these aspects are dealt with in detail in this talk

  2. Nuclear magnetic resonance. Applications to medicine and biology

    International Nuclear Information System (INIS)

    Berdugo, M.; Fauchet, M.; Menasche, P.; Grall, Y.; Piwnica, A.

    1982-01-01

    Nuclear magnetic resonance (NMR) is a non-invasive exploratory technique based on a principle radically different from those of radiography, radionuclide exploration and ultrasonography. Signals coming from atomic nuclei and reflecting their density and chemical/biochemical environment are collected, thus providing information on the physiological and pathological state of tissues. The technique has multiple applications, either practical (tomographic imaging of the brain, thyroid gland and liver) or in the field of research, e.g. investigating ischaemic myocardial areas and pathological fluid composition, measuring intracellular pH, diagnosing the nature of a tumour and, broadly speaking, understanding the biochemical changes associated with malignant degeneration [fr

  3. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... interventions. Children's (pediatric) nuclear medicine refers to imaging examinations done in babies, young children and teenagers. Nuclear ... nuclear medicine procedure work? With ordinary x-ray examinations, an image is made by passing x-rays ...

  4. Pediatric nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    1986-01-01

    This symposium presented the latest techniques and approaches to the proper medical application of radionuclides in pediatrics. An expert faculty, comprised of specialists in the field of pediatric nuclear medicine, discussed the major indications as well as the advantages and potential hazards of nuclear medicine procedures compared to other diagnostic modalities. In recent years, newer radiopharmaceuticals labeled with technetium-99m and other short-lived radionuclides with relatively favorable radiation characteristics have permitted a variety of diagnostic studies that are very useful clinically and carry a substantially lower radiation burden then many comparable X-ray studies. This new battery of nuclear medicine procedures is now widely available for diagnosis and management of pediatric patients. Many recent research studies in children have yielded data concerning the effacacy of these procedures, and current recommendations will be presented by those involved in conducting such studies. Individual papers are processed separately for the Energy Data Base.

  5. Pediatric nuclear medicine

    International Nuclear Information System (INIS)

    1986-01-01

    This symposium presented the latest techniques and approaches to the proper medical application of radionuclides in pediatrics. An expert faculty, comprised of specialists in the field of pediatric nuclear medicine, discussed the major indications as well as the advantages and potential hazards of nuclear medicine procedures compared to other diagnostic modalities. In recent years, newer radiopharmaceuticals labeled with technetium-99m and other short-lived radionuclides with relatively favorable radiation characteristics have permitted a variety of diagnostic studies that are very useful clinically and carry a substantially lower radiation burden then many comparable X-ray studies. This new battery of nuclear medicine procedures is now widely available for diagnosis and management of pediatric patients. Many recent research studies in children have yielded data concerning the effacacy of these procedures, and current recommendations will be presented by those involved in conducting such studies. Individual papers are processed separately for the Energy Data Base

  6. Nuclear medicine tomorrow

    International Nuclear Information System (INIS)

    Marko, A.M.

    1986-04-01

    The purpose of this Workshop was to discuss and promote future nuclear medicine applications. Atomic Energy of Canada Limited (AECL) is determined to assist in this role. A major aim of this gathering was to form an interface that was meaningful, representative of the two entities, and above all, on-going. In the opening address, given by Mr. J. Donnelly, President of AECL, this strong commitment was emphasized. In the individual sessions, AECL participants outlined R and D programs and unique expertise that promised to be of interest to members of the nuclear medicine community. The latter group, in turn, described what they saw as some problems and needs of nuclear medicine, especially in the near future. These Proceedings comprise the record of the formal presentations. Additionally, a system of reporting by rapporteurs insured a summary of informal discussions at the sessions and brought to focus pertinent conclusions of the workshop attendees

  7. IAEA activities in nuclear medicine and related medical applications of nuclear techniques

    International Nuclear Information System (INIS)

    Dudley, R.A.

    1986-01-01

    One of the objectives of the International Atomic Energy Agency, as specified in its Statute, is to ''enlarge the contribution of atomic energy to peace, health and prosperity throughout the world.'' Its programmes in human health include both the exploitation and measurement of radiation fields (radiotherapy and dosimetry) and the use of radionuclides in an investigative or tracer role (the primary subject of this Symposium). The Agency carries out its programmes by means of several mechanisms. The technical co-operation programme, responding to requests for support from governments of Member States, is the dominant mechanism. Through it, experts may be made available to introduce new skills to a laboratory; essential equipment may be provided; and training may be organized in various forms. A second mechanism is the research contract programme, providing financial support to individual laboratories for particular research projects. A third mechanism is information exchange: scientific meetings, publications and the nuclear abstracts service of the International Nuclear Information System (INIS). In the field covered by this Symposium, the technical content of the projects supported by the Agency using these mechanisms may be classed in several categories. One domain that penetrates all others is instrumentation: selection, quality control and maintenance to prevent or correct breakdowns. Another category of activity, requiring the least sophisticated technology, is radioimmunoassay and related procedures. A third category involves the use of radionuclides in vivo, notably the classic applications of nuclear medicine in diagnosing the health status of individual patients, but including also investigation of the nature and aetiology of disease. A fourth category of project includes the study of the biological role of trace elements, especially by neutron activation analysis

  8. Coordination compounds in nuclear medicine

    International Nuclear Information System (INIS)

    Jurisson, S.; Berning, D.; Wei Jia; Dangshe Ma

    1993-01-01

    Radiopharmaceuticals, drugs containing a radionuclide, are used routinely in nuclear medicine departments for the diagnosis of disease and are under investigation for use in the treatment of disease. Nuclear medicine takes advantage of both the nuclear properties of the radionuclide and the pharmacological properties of the radiopharmaceutical. Herein lies the real strength of nuclear medicine, the ability to monitor biochemical and physiological functions in vivo. This review discusses the coordination chemistry that forms the basis for nuclear medicine applications of the FDA-approved radiopharmaceuticals that are in clinical use, and of the most promising diagnostic and therapeutic radiopharmaceuticals that are in various stages of development. 232 refs

  9. Clinical applications of PET-CT in nuclear medicine to medical specialists

    International Nuclear Information System (INIS)

    2012-08-01

    This regional training course about Clinical Applications of PET-Tc in nuclear medicine include: imaging, pathology, scintigraphy, computed tomography, radiology, endoscopy, magnetic resonance, biopsy, and histology. It also describes pathologies and diseases of organs and bone structures such as: musculoskeletal and osseous damage, tumors, fibroids, metastasize, neoplasm, adenopathies and cancer of liver, brain, glands, kidney, neck, thorax, lungs, uterus, ovaries, craniums, hypophysis etc

  10. An introduction to nuclear physics, with applications in medicine and biology

    International Nuclear Information System (INIS)

    Dyson, N.A.

    1981-01-01

    A concise account of the applications of nuclear physics to medical and biological science is given. Half the book is devoted to the basic aspects of nuclear and radiation physics such as interactions between radiation and matter, nuclear reactions and the production of isotopes, an introduction to α, β and γ-radiation detectors and finally the radiation from nuclear decay. Information is then given on the applications of radioisotopes and neutrons and other accelerator-based applications in medicine and biology. The book is aimed at not only those undergraduates and postgraduates who are devoting their main effort to medical physics, but also to those students who are looking primarily for an introduction to nuclear physics together with an account of some of the ways in which it impinges on the work of other scientists. (U.K.)

  11. Application of Balance Score Card (BSC) in a Nuclear Medicine Department

    International Nuclear Information System (INIS)

    Rayo, J.I.; Serrano, J.; Martin, R.; Corral, C.

    2002-01-01

    Balanced Scorecard (BSC) is a concept helping you translate strategy into action. BSC provides management with a comprehensive picture of business operations and a methodology that facilitates the communication and understanding of business goals and strategies at all levels of an organization. Traditional performance measurement, focusing on external accounting data, was quickly becoming obsolete and something more was needed to provide the information age enterprises with efficient planning tools, For this purpose Kaplan and Norton introduced four different perspectives. Aim: Application of BSC to a Nuclear Medicine Department for provides four perspectives: financial perspective, customer perspective, process perspective and learning and innovation perspective. Conclusion: BSC helps align key performance measures with strategy at all levels of a Nuclear Medicine Department, facilitates communication and understanding, provides feedback and learning and reduce the vast amount of information the Nuclear Medicine Department into essentials

  12. Nuclear medicine in Ghana

    International Nuclear Information System (INIS)

    Affram, R.K.; Kyere, K.; Amuasi, J.

    1991-01-01

    The background to the introduction and application of radioisotopes in medicine culminating in the establishment of the nuclear Medicine Unit at the Korle Bu Teaching Hospital, Ghana, has been examined. The Unit has been involved in important clinical researches since early 1970s but routine application in patient management has not always been possible because of cost per test and lack of continuous availability of convertible currency for the purchase of radioisotopes which are not presently produced by the National Nuclear Research Institute at Kwabenya. The capabilities and potentials of the Unit are highlighted and a comparison of Nuclear Medicine techniques to other medical diagnostic and imaging methods have been made. There is no organised instruction in the principles of medical imaging and diagnostic methods at both undergraduate and postgraduate levels in Korle Bu Teaching Hospital which has not promoted the use of Nuclear Medicine techniques. The development of a comprehensive medical diagnostic and imaging services is urgently needed. (author). 18 refs., 3 tabs

  13. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... are small, diagnostic nuclear medicine procedures result in low radiation exposure, acceptable for diagnostic exams. Thus, the radiation risk is very low compared with the potential benefits. Nuclear medicine diagnostic ...

  14. Children's (Pediatric) Nuclear Medicine

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    Full Text Available ... What are some common uses of the procedure? Children's (pediatric) nuclear medicine imaging is performed to help diagnose childhood disorders that are congenital (present at birth) or that develop during childhood. Physicians use nuclear medicine imaging to ...

  15. Children's (Pediatric) Nuclear Medicine

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    Full Text Available ... Nuclear Medicine Children’s (pediatric) nuclear medicine imaging uses small amounts of radioactive materials called radiotracers, a special ... is a branch of medical imaging that uses small amounts of radioactive material to diagnose and determine ...

  16. Children's (Pediatric) Nuclear Medicine

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    Full Text Available ... Tell your doctor about your child’s recent illnesses, medical conditions, medications and allergies. Depending on the type ... Nuclear Medicine? Nuclear medicine is a branch of medical imaging that uses small amounts of radioactive material ...

  17. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... Because nuclear medicine procedures are able to pinpoint molecular activity within the body, they offer the potential ... or imaging device that produces pictures and provides molecular information. In many centers, nuclear medicine images can ...

  18. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... MRI. top of page What are some common uses of the procedure? Children's (pediatric) nuclear medicine imaging ... at birth) or that develop during childhood. Physicians use nuclear medicine imaging to evaluate organ systems, including ...

  19. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... child is taking as well as vitamins and herbal supplements and if he or she has any ... What are the limitations of Children's (Pediatric) Nuclear Medicine? Nuclear medicine procedures can be time consuming. It ...

  20. Children's (Pediatric) Nuclear Medicine

    Medline Plus

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  1. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... that are congenital (present at birth) or that develop during childhood. Physicians use nuclear medicine imaging to evaluate organ ... Nuclear medicine scans are typically used to ...

  2. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... referring physician. top of page What are the benefits vs. risks? Benefits The information provided by nuclear medicine examinations is ... risk is very low compared with the potential benefits. Nuclear medicine diagnostic procedures have been used for ...

  3. Children's (Pediatric) Nuclear Medicine

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    Full Text Available ... Nuclear Medicine? Nuclear medicine is a branch of medical imaging that uses small amounts of radioactive material to ... a radiologist or other physician. To locate a medical imaging or radiation oncology provider in your community, you ...

  4. Nuclear medicine

    International Nuclear Information System (INIS)

    Price, D.C.

    1989-01-01

    The spleen is a sinusoidal vascular filter that is an integral part of the reticuloendothelial system and is the largest single lymphoid organ in the body. Thus it has important scavenging and immunologic functions in humans. It is also a site for normal hematopoiesis in humans during the third to sixth months of gestation. Solenic hematopoiesis does occur normally in adult animals of other species (for instance, mouse, rat, rabbit), but it is seen postnatally in humans only when they have certain hematologic disorders such as myelofibrosis with myeloid metaplasia and severe hemolytic anemias. In its role as a reticuloendothelial organ the adult human spleen serves as a vascular scavenger. Arterial blood filters through a network of arterioles, cords, and sinuses in a closed system that requires the blood cells to be pliable and brings them into intimate contact with macrophages suspended on the reticulin stroma of the cords. Erythrocyte culling and pitting functions as described by Crosby result in a transient retention of immature circulating erythroid cells until residual intracellular nuclear fragments have been extruded. The increased risk for overwhelming infection in children and adults whose spleen have been removed for reasons other than acute trauma would appear to be caused by the loss of both its phagocytic and its immunologic (antibody-producing) contributions to the monitoring of the circulating blood. This paper reports that the ability of the spleen to phagocytose intravascular foreign particles and to recognize and destroy damaged erythrocytes is the basis for the current use of radiopharmaceuticals in spleen scintigraphy

  5. Applications of CdTe to nuclear medicine. Annual report, February 1, 1979-January 31, 1980

    International Nuclear Information System (INIS)

    Entine, G.

    1980-01-01

    The application of CdTe gamma detectors in nuclear medicine is reported on. An internal probe was developed which can be inserted into the heart to measure the efficiency of various radiopharmaceuticals in the treatment of heart attacks. A second application is an array of detectors which is light enough to be worn by ambulatory patients and can measure the change in cardiac output over an eight hour period during heart attack treatment. The instrument includes an on board tape recorder

  6. Nuclear medicine imaging in clinical practice: Current applications and future trends

    International Nuclear Information System (INIS)

    Galli, G.; Maini, C.L.

    1985-01-01

    The following conclusions can be drawn: 1) Even though developments in data digitalization enable also other imaging techniques to extract functional information, it is likely that nuclear medicine will keep and possibly increase its key role for functional studies requiring quantitative data analyses. This statement is true at present and it will probably remain true for a long time to come. 2) Nuclear medicine is and will remain an important clinical tool also for morphological or morphodynamic studies in selected situations. Of course the integration of nuclear medicine studies with other diagnostic procedures is highly desirable. The highest clinical yield of multi-test diagnostic protocols will be anyway obtained by the wisest physician as sophysticated technology is no substitution for intelligent clinical judgment. 3) The development of new radiopharmaceuticals with well characterized biokinetic features allowing precise tissue characterization opens new frontiers to be exploited by nuclear medicine centers equipped with conventional technology (digital gammacameras, SPECT). 4) Positron emission tomography is the most important new development of nuclear medicine imaging. Not only PET has already shown its enormous possibilities for physiological and pathophysiological studies, but the clinical relevance of selected applications has been proved. More experience is however needed to assess systematically the whole impact of PET studies in clinical practice and to perform dependable cost/benefit studies. 5) Among all other imaging techniques NMR is the closest to nuclear medicine because of a strict ''compatibility of aptitudes, training and methodology'' (4). Accordingly future improvements of both methods will be better achieved if they could be integrated and the results compared with the same institutions

  7. Peptide radiopharmaceuticals in nuclear medicine

    International Nuclear Information System (INIS)

    Blok, D.; Vermeij, P.; Feitsma, R.I.J.; Pauwels, E.J.K.

    1999-01-01

    This article reviews the labelling of peptides that are recognised to be of interest for nuclear medicine or are the subject of ongoing nuclear medicine research. Applications and approaches to the labelling of peptide radiopharmaceuticals are discussed, and drawbacks in their development considered. (orig.)

  8. Nuclear Medicine week in Colombia

    International Nuclear Information System (INIS)

    Padhy, A.K.

    2003-01-01

    During the week of 6-12 October 2003 the IAEA organized a Research Coordination Meeting on 'Relationship between lower Respiratory Tract Infection, Gastroesophageal reflux and bronchial Asthma in children' at Hospital San Ignacio in Bogota. Besides there were four workshops in Bogota; workshops on Bone infection and Bone scan in Pediatric ortopaedics at Hospital Militar and Fundacion CardioInfantil, a workshop for Nuclear Medicine Technologists and a workshop on Sentinel Lymph Node mapping and Surgical Gamma Probe Application at Institute of Oncology. A nuclear cardiology workshop was organized in Medellin, and finally crowning them all was the 9th Congress of the Colombian Association of Nuclear Medicine at Cali from 10-12 October, 2003; probably the largest and best Colombian nuclear medicine congress every held in the country. A workshop was also organized in Cali for nuclear medicine technologists in conjunction with the Annual Convention. It was a mix of IAEA's Technical Cooperation and Regular Budget activities along with the activities of Colombian Association of Nuclear Medicine, bringing in absolute synergy to galvanize the entire nuclear medicine community of the country. The week saw nuclear medicine scientists from more than 20 IAEA Member States converging on Colombia to spread the message of nuclear medicine, share knowledge and to foster International understanding and friendship among the nuclear medicine people of the world

  9. Application of nuclear techniques in agriculture and medicine: the TRNC experience

    International Nuclear Information System (INIS)

    Senvar, C.; Korkut, F.C.

    2002-01-01

    As a small island State in the Eastern corner of the Mediterranean, better known for its potential in academia and tourism, the Turkish Republic of Northern Cyprus (TRNC) is not a country which produces or uses nuclear energy. Nevertheless, in order to safeguard against the biological effects of radiation, the TRNC benefits from nuclear sciences and techniques. In order to ensure the safety of agricultural produce, apart from utilizing nuclear medicine and Co60 (cobalt 60) therapy and similar applications, gamma spectrometric measurements are also undertaken by the State Laboratories which is attached to the Ministry of Health and Social Welfare. Similar techniques are used to measure radioactive content in environmental (sea water, soil, rocks, etc.) samples. All facilities in the TRNC which utilize nuclear agents in the field of medicine, including the X-Ray Screening centers, are subject to control and supervision in accordance with relevant regulations and waste disposal is carried out in cooperation with the Turkish Atomic Energy Authority (TAEK). Just as nuclear techniques can be used for peaceful purposes in such fields as agriculture, control of food-borne diseases, medicine and industry, it can also be abused. In awareness of the global threat of the illicit trafficking of nuclear materials and radioactive sources and given its geo-strategic location at the crossroads of Europe, the Middle East and North Africa, the TRNC has taken all the necessary measures, within the context of combating terrorism, to prevent illicit trafficking as such

  10. Prospects in nuclear medicine

    International Nuclear Information System (INIS)

    Pink, V.; Johannsen, B.; Muenze, R.

    1990-01-01

    In nuclear medicine, a sequence of revolutioning research up to the simple and efficient application in routine has always then taken place when in an interdisciplinary teamwork new radiochemical tracers and/or new instrumentation had become available. At present we are at the beginning of a phase that means to be in-vivo-biochemistry, the targets of which are molecular interactions in the form of enzymatic reactions, ligand-receptor interactions or immunological reactions. The possibility to use positron-emitting radionuclides of bioelements in biomolecules or drugs to measure their distribution in the living organism by positron-emission tomography (PET) is gaining admittance into the pretentious themes of main directions of medical research. Diagnostic routine application of biochemically oriented nuclear medicine methods are predominantly expected from the transmission of knowledge in PET research to the larger appliable emission tomography with gamma-emitting tracers (SPECT). (author)

  11. Veterinary nuclear medicine

    International Nuclear Information System (INIS)

    Krzeminski, M.; Lass, P.; Teodorczyk, J.; Krajka, J.

    2004-01-01

    The veterinary use of radionuclide techniques dates back to the mid-sixties, but its more extensive use dates back to the past two decades. Veterinary nuclear medicine is focused mainly on four major issues: bone scintigraphy - with the majority of applications in horses, veterinary endocrinology - dealing mainly with the problems of hyperthyreosis in cats and hyperthyreosis in dogs, portosystemic shunts in small animals and veterinary oncology, however, most radionuclide techniques applied to humans can be applied to most animals. (author)

  12. Fundamentals of nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Alazraki, N.P.; Mishkin, F.S.

    1984-01-01

    This guidebook for clinical nuclear medicine is written as a description of how nuclear medicine procedures should be used by clinicians in evaluating their patients. It is designed to assist medical students and physicians in becoming acquainted with nuclear medicine techniques for detecting and evaluating most common disorders. The material provides an introduction to, not a textbook of, nuclear medicine. Each chapter is devoted to a particular organ system or topic relevant to the risks and benefits involved in nuclear medicine studies. The emphasis is on presenting the rationales for ordering the various clinical imaging procedures performed in most nuclear medicine departments. Where appropriate, alternative imaging modalities including ultrasound, computed tomography imaging, and radiographic special procedures are discussed. Comparative data between nuclear medicine imaging and other modalities are presented to help guide the practicing clinician in the selection of the most appropriate procedure for a given problem.

  13. SPECT/CT: main applications in nuclear medicine

    International Nuclear Information System (INIS)

    Perera Pintado, Alejandro; Torres Aroche, Leonel A.; Vergara Gil, Alex; Batista Cuéllar, Juan F.; Prats Capote, Anaís

    2017-01-01

    SPECT/CT has represented not only the possibility of acquiring anatomical and functional images in one single study, but also a revolution for the clinical management of several diseases, taking the better of each one of these imaging modalities. The present work is aimed at presenting an overview of the most important applications of the SPECT/CT in the field of oncology, cardiology and neurology. New technological advances in the design of innovative solid state detectors and related equipment have had a positive effect on the performance of this kind of dual modality. This hybrid technique improves the sensitivity and the specificity of gammagraphic studies, as well as shortens the acquisition times and gives attenuation correction of co-registered images, which, in turn, makes their analysis easier. Some of the main applications for the study of oncological diseases are the following: localization and follow-up of different kinds of tumors, their metastasis and relapses, as well as the optimization of radiotherapy doses. This technique has been useful to evaluate the coronary artery disease allowing an adequate attenuation correction of images, the determination of calcium score, and performing angio-CT studies, according to the CT quality. SPECT/CT has also gained ground in the assessment of some neurological diseases. Conclusions: The introduction of new technological advances and radiopharmaceuticals thus predicting a more relevant place for SPECT/CT in clinical practice. (author)

  14. Nuclear power in human medicine

    International Nuclear Information System (INIS)

    Kuczera, Bernhard

    2012-01-01

    The public widely associate nuclear power with the megawatt dimensions of nuclear power plants in which nuclear power is released and used for electricity production. While this use of nuclear power for electricity generation is rejected by part of the population adopting the polemic attitude of ''opting out of nuclear,'' the application of nuclear power in medicine is generally accepted. The appreciative, positive term used in this case is nuclear medicine. Both areas, nuclear medicine and environmentally friendly nuclear electricity production, can be traced back to one common origin, i.e. the ''Atoms for Peace'' speech by U.S. President Eisenhower to the U.N. Plenary Assembly on December 8, 1953. The methods of examination and treatment in nuclear medicine are illustrated in a few examples from the perspective of a nuclear engineer. Nuclear medicine is a medical discipline dealing with the use of radionuclides in humans for medical purposes. This is based on 2 principles, namely that the human organism is unable to distinguish among different isotopes in metabolic processes, and the radioactive substances are employed in amounts so small that metabolic processes will not be influenced. As in classical medicine, the application of these principles serves two complementary purposes: diagnosis and therapy. (orig.)

  15. I-124 and its applications in nuclear medicine and biology

    International Nuclear Information System (INIS)

    Weinreich, R.; Wyer, L.; Crompton, N.; Nievergelt-Egido, M.C.; Guenther, I.; Roelcke, U.; Leenders, K.L.; Knust, E.J.; Blasberg, R.G.

    1998-01-01

    4.15-d 124 I decays simultaneously by positron emission (25.6 %) and by electron capture (74.4 %). This dualistic decay allows in principle to use 124 I in both diagnostic and therapeutic approaches. In some high-current measurements, 124 I was produced via the nuclear reaction 124 Te(p,n) 124 I using 12.6 MeV protons in yields 25% below those of the mainly used reaction 124 Te(d,2n) 124 I, but with a very much lower contamination by long-lived 125 I and 126 I. The minimum obtained value for the sum of all impurities was 0.14% of the 124 I activity, at 6 days after end of bombardment, using 99.8% enriched 124 TeO 2 as target material. This yield/purity ratio also permits the production of 124 I by low-energy ''baby'' cyclotrons which could considerably increase the general availability of this nuclide. [ 124 ]IUdR was synthesized by direct electrophilic labelling in good yield (45-65 %), high radiochemical purity (>95%) and high specific activity for functional PET imaging of brain tumours. One day after administration to patients and after completion of the ''washout'', the only remaining activity was that in tumour structures. The comparison with the tumour labelling index showed that PET with [ 124 ]IUdR introduces a novel imaging approach: tumour diagnostics by the measurement of cell proliferation. [ 124 ]IodoHoechst 33258 was synthesized by direct electrophilic labelling in yields of 70 % and in a radiochemical purity of 99 %. In cell culture experiments using HTB-40 (human adenocarcinoma line), it was shown to be taken up by the DNA as well as the unlabelled fluorescence dye H 33258. Furthermore, its radiobiological activity was equal to that of the 125 I-labelled H 33258, but markedly stronger than that of the 131 I-labelled derivative. This suggests a mechanism for Auger-electron induced radiobiological activity as a novel therapeutical approach. p-[ 124 ]Iodophenylalanine and [ 124 ]iodo-α-methyltyrosine are two other compounds labelled with 124 I that

  16. Nuclear Medicine Practice in Kenya

    International Nuclear Information System (INIS)

    Ndirangu, T.D.

    2017-01-01

    Nuclear medicine is a medical specialty that relies on the use of nuclear technology in the diagnosis and treatment (therapy) of diseases. Nuclear medicine uses the principle that a certain radiopharmaceutical (tracer) will at a certain point in time have a preferential uptake by a particular body, tissue or cell. This uptake is then imaged by the use of detectors mounted in gamma cameras or PET (positron emission tomography) devices.. Unlike other radiation applications for medical use, nuclear medicine uses open (unsealed) sources of radiation. In a country with an estimated population of 48 million in 2017, Kenya has only two (2) nuclear medicine facilities (units). Being a relatively new medical discipline in Kenya, several measures have been taken by the clinical nuclear medicine team to create awareness at various levels

  17. Applications of artificial neural networks in Nuclear Medicine

    International Nuclear Information System (INIS)

    Maddalena, D.J.

    1993-01-01

    Artificial neural networks (ANNs) are computer-based mathematical models developed to have analogous functions to idealized simple biological nervous systems. They consist of layers of processing elements, which are considered to be analogous to the nerve cells (neurons) and these are interconnected to form a network which is in essence a parallel computer even though they are most likely to be run on non-parallel computers such as personal computers or workstations. The parallel processing nature of the ANNs gives them the characteristics of speed, reliability and generalisation. The speed occurs because many bits of information can be input and analysed simultaneously. Reliability occurs because the networks can produce reasonable results even when some input data are missing or inaccurate. Generalisation is the ability of the network to estimate reasonable results when faced with new data outside its normal range of experience. There are two main classes of ANN - supervised and un-supervised. Supervised ANNs are trained to build internal algorithms relating patterns of inputs to outputs. After learning the relationship between the inputs and outputs they are able to classify patterns and make decisions of predictions based upon new patterns of inputs. The most frequently used ANN for biomedical applications is a supervised type called the back propagation ANN which has an excellent ability to predict and classify data and is becoming commonly used throughout the biomedical field. This article will discuss back propagation ANN structure. Its use for image analysis and diagnostic classification in various imaging modalities including Single Photon Emission Computed Tomography and Positron Emission Tomography 17 refs., 2 figs

  18. Array processors: an introduction to their architecture, software, and applications in nuclear medicine

    International Nuclear Information System (INIS)

    King, M.A.; Doherty, P.W.; Rosenberg, R.J.; Cool, S.L.

    1983-01-01

    Array processors are ''number crunchers'' that dramatically enhance the processing power of nuclear medicine computer systems for applicatons dealing with the repetitive operations involved in digital image processing of large segments of data. The general architecture and the programming of array processors are introduced, along with some applications of array processors to the reconstruction of emission tomographic images, digital image enhancement, and functional image formation

  19. Well scintillation counting systems for nuclear medicine applications in developing countries

    International Nuclear Information System (INIS)

    1977-01-01

    This report of a consultants' meeting, organized by the Medical Applications Section of the Division of Life Sciences, IAEA, during the period 23-25 May 1977, examines well scintillation counting systems in the light of the requirements of laboratories in developing countries. It has three facets: 1) identification of the most rewarding applications of nuclear medicine techniques, 2) identification of favourable design attributes of instruments used in such applications, and 3) development of maintenance strategies to assure reliable performance of the instruments once put into service. Some characteristics of commercially available well scintillation counting systems are given

  20. Imaging in nuclear medicine

    CERN Document Server

    Hoeschen, Christoph

    2013-01-01

    This volume addresses a wide range of issues in the field of nuclear medicine imaging, with an emphasis on the latest research findings. Initial chapters set the scene by considering the role of imaging in nuclear medicine from the medical perspective and discussing the implications of novel agents and applications for imaging. The physics at the basis of the most modern imaging systems is described, and the reader is introduced to the latest advances in image reconstruction and noise correction. Various novel concepts are then discussed, including those developed within the framework of the EURATOM FP7 MADEIRA research project on the optimization of imaging procedures in order to permit a reduction in the radiation dose to healthy tissues. Advances in quality control and quality assurance are covered, and the book concludes by listing rules of thumb for imaging that will be of use to both beginners and experienced researchers.

  1. Reactor production and processing of radioisotopes for therapeutic applications in nuclear medicine

    International Nuclear Information System (INIS)

    Knapp, F.F. Jr.; Mirzadeh, S.; Beets, A.L.

    1995-01-01

    Nuclear reactors continue to play an important role in providing radioisotopes for nuclear medicine. Many reactor-produced radioisotopes are ''neutron rich'' and decay by beta-emission and are thus of interest for therapeutic applications. This talk discusses the production and processing of a variety of reactor-produced radioisotopes of current interest, including those produced by the single neutron capture process, double neutron capture and those available from beta-decay of reactorproduced radioisotopes. Generators prepared from reactorproduced radioisotopes are of particular interest since repeated elution inexpensively provides many patient doses. The development of the alumina-based W-188/Re-188 generator system is discussed in detail

  2. Fundamentals of nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Alazraki, N.P.; Mishkin, F.S.

    1988-01-01

    The book begins with basic science and statistics relevant to nuclear medicine, and specific organ systems are addressed in separate chapters. A section of the text also covers imaging of groups of disease processes (eg, trauma, cancer). The authors present a comparison between nuclear medicine techniques and other diagnostic imaging studies. A table is given which comments on sensitivities and specificities of common nuclear medicine studies. The sensitivities and specificities are categorized as very high, high, moderate, and so forth.

  3. Fundamentals of nuclear medicine

    International Nuclear Information System (INIS)

    Alazraki, N.P.; Mishkin, F.S.

    1988-01-01

    The book begins with basic science and statistics relevant to nuclear medicine, and specific organ systems are addressed in separate chapters. A section of the text also covers imaging of groups of disease processes (eg, trauma, cancer). The authors present a comparison between nuclear medicine techniques and other diagnostic imaging studies. A table is given which comments on sensitivities and specificities of common nuclear medicine studies. The sensitivities and specificities are categorized as very high, high, moderate, and so forth

  4. Application of ISO 9001:2000 in a Nuclear Medicine Department

    International Nuclear Information System (INIS)

    Rayo, J.I.; Serrano, J.; Martin, R.; Corral, C.

    2002-01-01

    Since 1947 ISO has been developing voluntary technical standards over almost all sectors of business, industry, and technology. The ISO 9000 standards were published in 1987, and new versions of the standards saw daylight in 1994 and 2000. The highlights of ISO 9001:2000 are: quality management system, management responsibility, resource management, product realization and measurement, analysis and improvement. Aim: Application of ISO 9001:2000 to a Nuclear Medicine Department for provides the organization with a model to follow, customer focus, people will understand the goals of the organization and are motivated to work for objectives and lower costs and shorter cycle times through effective use of resources. Conclusion: ISO 9001:2000 focuses on continual improvement of business processes that should be a permanent objective of the Nuclear Medicine Department

  5. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... variety of diseases, including many types of cancers, heart disease, gastrointestinal, endocrine, neurological disorders and other abnormalities within the body. Because nuclear medicine procedures are ...

  6. Imaging in nuclear medicine

    International Nuclear Information System (INIS)

    Giussani, Augusto; Hoeschen, Christoph

    2013-01-01

    Presents the most recent developments in nuclear medicine imaging, with emphasis on the latest research findings. Considers the latest advances in imaging systems, image reconstruction, noise correction, and quality assurance. Discusses novel concepts, including those developed within the framework of the EURATOM FP7 MADEIRA project. Lists rules of thumb for imaging of use to both beginners and experienced researchers. This volume addresses a wide range of issues in the field of nuclear medicine imaging, with an emphasis on the latest research findings. Initial chapters set the scene by considering the role of imaging in nuclear medicine from the medical perspective and discussing the implications of novel agents and applications for imaging. The physics at the basis of the most modern imaging systems is described, and the reader is introduced to the latest advances in image reconstruction and noise correction. Various novel concepts are then discussed, including those developed within the framework of the EURATOM FP7 MADEIRA research project on the optimization of imaging procedures in order to permit a reduction in the radiation dose to healthy tissues. Advances in quality control and quality assurance are covered, and the book concludes by listing rules of thumb for imaging that will be of use to both beginners and experienced researchers.

  7. Imaging in nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Giussani, Augusto [BfS - Federal Office for Radiation Protection, Oberschleissheim (Germany). Dept. of Radiation Protection and Health; Hoeschen, Christoph (eds.) [Helmholtz Zentrum Muenchen - German Research Center for Environmental Health, Neuherberg (Germany). Research Unit Medical Raditation Physics and Diagnostics

    2013-08-01

    Presents the most recent developments in nuclear medicine imaging, with emphasis on the latest research findings. Considers the latest advances in imaging systems, image reconstruction, noise correction, and quality assurance. Discusses novel concepts, including those developed within the framework of the EURATOM FP7 MADEIRA project. Lists rules of thumb for imaging of use to both beginners and experienced researchers. This volume addresses a wide range of issues in the field of nuclear medicine imaging, with an emphasis on the latest research findings. Initial chapters set the scene by considering the role of imaging in nuclear medicine from the medical perspective and discussing the implications of novel agents and applications for imaging. The physics at the basis of the most modern imaging systems is described, and the reader is introduced to the latest advances in image reconstruction and noise correction. Various novel concepts are then discussed, including those developed within the framework of the EURATOM FP7 MADEIRA research project on the optimization of imaging procedures in order to permit a reduction in the radiation dose to healthy tissues. Advances in quality control and quality assurance are covered, and the book concludes by listing rules of thumb for imaging that will be of use to both beginners and experienced researchers.

  8. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... physician who has specialized training in nuclear medicine will interpret the images and send a report to your referring physician. top of page What are the benefits vs. risks? Benefits The information provided by nuclear ...

  9. Nuclear techniques in medicine

    International Nuclear Information System (INIS)

    Basson, J.K.

    1984-01-01

    The use of nuclear techniques in medicine has, also in South Africa, increased enormously, especially as regards diagnosis and reseach. In 1983 in vivo tests with radioisotopes were carried out and also in vitro tests, mainly by radioimmunoassay. Therapy with open and sealed radioactive sources was concentrated mainly on cancer treatments. In 1983 NUCOR supported 83 research projects in the life sciences. Imaging of organs or tissues in the body with nuclear techniques has developed into the most important application of nuclear medicine, with the development of even more specific labelled compounds as the main objective. Radioimmunoassay is at an exciting watershed, now that labelled monoclonal antibodies with high specificity for early diagnosis (also in cancer) and even localised radiotherapy have become available. The establishment of the 200 MeV open-sector cyclotron by the National Accelerator Centre also for medical purposes will, in addition to the large-scale production of the protonrich isotopes, also make a substantial contribution to radiotherapy with nuclear particles such as neutrons, protons and helium-3

  10. PACS in nuclear medicine

    International Nuclear Information System (INIS)

    Kang, Keon Wook

    2000-01-01

    PACS (Picture Archiving and Communication System) is being rapidly spread and installed in many hospitals, but most of the system do not include nuclear medicine field. Although additional costs of hardware for nuclear medicine PACS is low, the complexity in developing viewing software and little market have made the nuclear medicine PACS not popular. Most PACS utilize DICOM 3.0 as standard format, but standard format in nuclear medicine has been Interfile. Interfile should be converted into DICOM format if nuclear images are to be stored and visualized in most PACS. Nowadays, many vendors supply the DICOM option in gamma camera and PET. Several hospitals in Korea have already installed nucler PACS with DICOM, but only the screen captured images are supplied. Software for visualizing pseudo-color with color lookup tables and expressing with volume view should be developed to fulfill the demand of referring physicians and nuclear medicine physicians. PACS is going to integrate not only radiologic images but also endoscopic and pathologic images. Web and PC based PACS is now a trend and is much compatible with nuclear medicine PACS. Most important barrier for nuclear medicine PACS that we encounter is not a technical problem, but indifference of investor such as administrator of hospital or PACS. Now it is time to support and invest for the development of nuclear medicine PACS

  11. Recent history of nuclear medicine

    International Nuclear Information System (INIS)

    Potchen, E.J.; Gift, D.A.

    1988-01-01

    Diagnostic nuclear medicine's recent history is characterized both by significant change and by growing participation in efforts to quantify the impact of nuclear medicine procedures on clinical judgment and patient management, as well as to develop methods for studying the efficacy of diagnostic procedures in general. The replacement of many nuclear medicine procedures that at one time were considered essential standards of clinical care by newer, more efficient and effective modalities has been complimented by the continued development of increasingly sophisticated applications of scintigraphic tracer methods

  12. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... resume his/her normal activities after the nuclear medicine scan. If the child has been sedated, you will receive specific instructions ... usually mild. Nevertheless, you should inform the nuclear medicine personnel of any allergies your child may have or other problems that may have ...

  13. Energetic electron processes fluorescence effects for structured nanoparticles X-ray analysis and nuclear medicine applications

    Energy Technology Data Exchange (ETDEWEB)

    Taborda, A.; Desbrée, A. [Institut de Radioprotection et de Sûreté Nucléaire (IRSN), PRP-HOM/SDI/LEDI, BP-17, 31, Avenue de la Division Leclerc, 92262 Fontenay-aux-Roses (France); Carvalho, A. [IEQUALTECS, Lda, Rua Dr. Francisco Sá Carneiro, 36, 2500-065 S. Gregório CLD (Portugal); Chaves, P.C. [C" 2TN, Campus Tecnológico e Nuclear, Instituto Superior Técnico, Universidade de Lisboa, EN10 km 139.7, 2685-066 Bobadela LRS (Portugal); Reis, M.A., E-mail: mareis@ctn.tecnico.ulisboa.pt [IEQUALTECS, Lda, Rua Dr. Francisco Sá Carneiro, 36, 2500-065 S. Gregório CLD (Portugal); C" 2TN, Campus Tecnológico e Nuclear, Instituto Superior Técnico, Universidade de Lisboa, EN10 km 139.7, 2685-066 Bobadela LRS (Portugal)

    2016-08-15

    Superparamagnetic iron oxide (SPIO) nanoparticles are widely used as contrast agents for nuclear magnetic resonance imaging (MRI), and can be modified for improved imaging or to become tissue-specific or even protein-specific. The knowledge of their detailed elemental composition characterisation and potential use in nuclear medicine applications, is, therefore, an important issue. X-ray fluorescence techniques such as particle induced X-ray emission (PIXE) or X-ray fluorescence spectrometry (XRF), can be used for elemental characterisation even in problematic situations where very little sample volume is available. Still, the fluorescence coefficient of Fe is such that, during the decay of the inner-shell ionised atomic structure, keV Auger electrons are produced in excess to X-rays. Since cross-sections for ionisation induced by keV electrons, for low atomic number atoms, are of the order of 10{sup 3} barn, care should be taken to account for possible fluorescence effects caused by Auger electrons, which may lead to the wrong quantification of elements having atomic number lower than the atomic number of Fe. Furthermore, the same electron processes will occur in iron oxide nanoparticles containing {sup 57}Co, which may be used for nuclear medicine therapy purposes. In the present work, simple approximation algorithms are proposed for the quantitative description of radiative and non-radiative processes associated with Auger electrons cascades. The effects on analytical processes and nuclear medicine applications are quantified for the case of iron oxide nanoparticles, by calculating both electron fluorescence emissions and energy deposition on cell tissues where the nanoparticles may be embedded.

  14. Digital filtering in nuclear medicine

    International Nuclear Information System (INIS)

    Miller, T.R.; Sampathkumaran, S.

    1982-01-01

    Digital filtering is a powerful mathematical technique in computer analysis of nuclear medicine studies. The basic concepts of object-domain and frequency-domain filtering are presented in simple, largely nonmathemaical terms. Computational methods are described using both the Fourier transform and convolution techniques. The frequency response is described and used to represent the behavior of several classes of filters. These concepts are illustrated with examples drawn from a variety of important applications in nuclear medicine

  15. Nuclear medicine. La medecine nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Blanquet, P; Blanc, D

    1976-01-01

    The applications of radioisotopes in medical diagnostics are briefly reviewed. Each organ system is considered and the Nuclear medicine procedures pertinent to that system are discussed. This includes, the principle of the test, the detector and the radiopharmaceutical used, the procedure followed and the clinical results obtained. The various types of radiation detectors presently employed in Nuclear Medicine are surveyed, including scanners, gamma cameras, positron cameras and procedures for obtaining tomographic presentation of radionuclide distributions.

  16. Nuclear medicine in cardiology

    Energy Technology Data Exchange (ETDEWEB)

    Torizuka, K.; Ishii, Y.; Yonekura, Y.; Yamamoto, K.; Tamaki, N. (Kyoto Univ. (Japan). Faculty of Medicine)

    1981-02-01

    Nuclear medicine in cardiology was reviewed. Electrocardiogram is obtained from the ..gamma..-ray measurement of a tracer by a single detector, which enables a bedsidemonitoring. Resolution and sensitivity are high and nuclear stethoscope with a computer is applicable for a background treatment. Myocardium is imaged by /sup 201/Tl scintigraphy. Relative difference of the perfusion indicates the ischemia which gaives roughly the size and portion of myocardial infarction. For transient ischemia stress myocardial perfusion imaging (SMPI) is also used. sup(99m)Tc pyrophosphate provides a clear image for myocardial infarction. Angiocardiogram is obtained repeatedly, by a single administration, using an equilibrium method. An attempt of three-dimensional display by 7 pin hole collimator and positron CT are also discussed.

  17. Hybrid MWPC gamma ray detecting system for applications in nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Bateman, J E; Connolly, J F [Science Research Council, Chilton (UK). Rutherford Lab.

    1978-10-15

    Results are presented from prototype MWPC gas-solid hybrid imaging detectors designed for applications in nuclear medicine. Using a multi-section chamber with foil converter cathodes and a delay line readout technique, the authors have made a sup(99m)Tc imaging detector with a spatial resolution of 5 mm fwhm and a projected quantum efficiency of 15% for a full scale device. With lead foil cathodes the detector design yields similar spatial resolution and quantum efficiency when positron annihilation gammas are detected. Images of positron emitters (/sup 22/Na and /sup 68/Ga) are presented.

  18. Quantitative nuclear medicine imaging: application of computers to the gamma camera and whole-body scanner

    International Nuclear Information System (INIS)

    Budinger, T.F.

    1974-01-01

    The following topics are reviewed: properties of computer systems for nuclear medicine quantitation; quantitative information concerning the relation between organ isotope concentration and detected projections of the isotope distribution; quantitation using two conjugate views; three-dimensional reconstruction from projections; quantitative cardiac radioangiography; and recent advances leading to quantitative nuclear medicine of clinical importance. (U.S.)

  19. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... by Image/Video Gallery Your Radiologist Explains Nuclear Medicine Transcript Welcome to Radiology Info dot org Hello! ... d like to talk to you about nuclear medicine. Nuclear medicine offers the potential to identify disease ...

  20. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... Sponsored by Image/Video Gallery Your Radiologist Explains Nuclear Medicine Transcript Welcome to Radiology Info dot org ... I’d like to talk to you about nuclear medicine. Nuclear medicine offers the potential to identify ...

  1. Nuclear medicine in psychiatry

    International Nuclear Information System (INIS)

    Lass, P.; Slawek, P.

    2007-01-01

    In the same way that the symptoms between different diseases in psychiatry overlap, functional brain research frequently shows the same pattern of changes across diagnostic borders; on the other hand, many the other tests, e.g. psychological tests, present the same problem as mentioned above; therefore: The psychiatrist seldom applies to an NM specialist to obtain a diagnosis; instead, a nuclear medicine report will rather confirm, or less frequently exclude, the psychiatrist's diagnosis. Ideally, psychiatric patients should be rescanned after the treatment, and changes in perfusion and/or metabolism discussed between psychiatrist and NM specialist. As shown above, there are few practical applications of nuclear medicine due to low specificity and low spatial resolution, although in the aspect of functional imaging it is still superior to CT/MRI, even in their functional modalities. On the other hand, its investigational potential is still growing, as there is no imaging technique in sight which could replace metabolic and receptor studies, and also because the scope of functional imaging in psychiatric diseases is spreading from its traditional applications, like dementia or depression, towards many poorly investigated fields e.g. hypnosis, suicidal behaviour or sleep disorders. (author)

  2. Nuclear medicine and mathematics

    Energy Technology Data Exchange (ETDEWEB)

    Pedroso de Lima, J.J. [Dept. de Biofisica e Proc. de Imagem, IBILI - Faculdade de Medicina, Coimbra (Portugal)

    1996-06-01

    The purpose of this review is not to present a comprehensive description of all the mathematical tools used in nuclear medicine, but to emphasize the importance of the mathematical method in nuclear medicine and to elucidate some of the mathematical concepts currently used. We can distinguish three different areas in which mathematical support has been offered to nuclear medicine: Physiology, methodology and data processing. Nevertheless, the boundaries between these areas can be indistinct. It is impossible in a single article to give even an idea of the extent and complexity of the procedures currently usede in nuclear medicine, such as image processing, reconstruction from projections and artificial intelligence. These disciplines do not belong to nuclear medicine: They are already branches of engineering, and my interest will reside simply in revealing a little of the elegance and the fantastic potential of these new `allies` of nuclear medicine. In this review the mathematics of physiological interpretation and methodology are considered together in the same section. General aspects of data-processing methods, including image processing and artificial intelligence, are briefly analysed. The mathematical tools that are most often used to assist the interpretation of biological phenomena in nuclear medicine are considered; these include convolution and deconvolution methods, Fourier analysis, factorial analysis and neural networking. (orig.)

  3. Nuclear medicine and mathematics

    International Nuclear Information System (INIS)

    Pedroso de Lima, J.J.

    1996-01-01

    The purpose of this review is not to present a comprehensive description of all the mathematical tools used in nuclear medicine, but to emphasize the importance of the mathematical method in nuclear medicine and to elucidate some of the mathematical concepts currently used. We can distinguish three different areas in which mathematical support has been offered to nuclear medicine: Physiology, methodology and data processing. Nevertheless, the boundaries between these areas can be indistinct. It is impossible in a single article to give even an idea of the extent and complexity of the procedures currently usede in nuclear medicine, such as image processing, reconstruction from projections and artificial intelligence. These disciplines do not belong to nuclear medicine: They are already branches of engineering, and my interest will reside simply in revealing a little of the elegance and the fantastic potential of these new 'allies' of nuclear medicine. In this review the mathematics of physiological interpretation and methodology are considered together in the same section. General aspects of data-processing methods, including image processing and artificial intelligence, are briefly analysed. The mathematical tools that are most often used to assist the interpretation of biological phenomena in nuclear medicine are considered; these include convolution and deconvolution methods, Fourier analysis, factorial analysis and neural networking. (orig.)

  4. Nuclear medicine statistics

    International Nuclear Information System (INIS)

    Martin, P.M.

    1977-01-01

    Numerical description of medical and biologic phenomena is proliferating. Laboratory studies on patients now yield measurements of at least a dozen indices, each with its own normal limits. Within nuclear medicine, numerical analysis as well as numerical measurement and the use of computers are becoming more common. While the digital computer has proved to be a valuable tool for measurment and analysis of imaging and radioimmunoassay data, it has created more work in that users now ask for more detailed calculations and for indices that measure the reliability of quantified observations. The following material is presented with the intention of providing a straight-forward methodology to determine values for some useful parameters and to estimate the errors involved. The process used is that of asking relevant questions and then providing answers by illustrations. It is hoped that this will help the reader avoid an error of the third kind, that is, the error of statistical misrepresentation or inadvertent deception. This occurs most frequently in cases where the right answer is found to the wrong question. The purposes of this chapter are: (1) to provide some relevant statistical theory, using a terminology suitable for the nuclear medicine field; (2) to demonstrate the application of a number of statistical methods to the kinds of data commonly encountered in nuclear medicine; (3) to provide a framework to assist the experimenter in choosing the method and the questions most suitable for the experiment at hand; and (4) to present a simple approach for a quantitative quality control program for scintillation cameras and other radiation detectors

  5. A concise guide to nuclear medicine

    CERN Document Server

    Elgazzar, Abdelhamid H

    2011-01-01

    Nuclear medicine is an important component of modern medicine. This easy-to-use book is designed to acquaint readers with the basic principles of nuclear medicine, the instrumentation used, the gamut of procedures available, and the basis for selecting specific diagnostic or therapeutic procedures and interpreting results. After an introductory chapter on the history, technical basis, and scope of nuclear medicine, a series of chapters are devoted to the application of nuclear medicine techniques in the different body systems. In addition, the use of nuclear medicine methods within oncology is

  6. Nuclear Medicine Annual, 1989

    International Nuclear Information System (INIS)

    Freeman, L.M.; Weissmann, H.S.

    1989-01-01

    Among the highlights of Nuclear Medicine Annual, 1989 are a status report on the thyroid scan in clinical practice, a review of functional and structural brain imaging in dementia, an update on radionuclide renal imaging in children, and an article outlining a quality assurance program for SPECT instrumentation. Also included are discussions on current concepts in osseous sports and stress injury scintigraphy and on correlative magnetic resonance and radionuclide imaging of bone. Other contributors assess the role of nuclear medicine in clinical decision making and examine medicolegal and regulatory aspects of nuclear medicine

  7. Nuclear tele medicine; Telemedicina nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Vargas, L.; Hernandez, F.; Fernandez, R. [Departamento de Medicina Nuclear, Imagenologia Diagnostica, Xalapa, Veracruz (Mexico)

    2005-07-01

    The great majority of the digital images of nuclear medicine are susceptible of being sent through internet. This has allowed that the work in diagnosis cabinets by image it can benefit of this modern technology. We have presented in previous congresses works related with tele medicine, however, due to the speed in the evolution of the computer programs and the internet, becomes necessary to make a current position in this modality of work. (Author)

  8. Cardiovascular nuclear medicine and MRI

    International Nuclear Information System (INIS)

    Reiber, J.H.C.; Wall, E.E. van der

    1992-01-01

    This book is based on a meeting of the Working Group on Nuclear Cardiology, which held March 22-23,1991 under the auspices of the European Society of Cardiology and the Interuniversity Cardiology Institute of the Netherlands, and on the Second International Symposium on Computer Applications in Nuclear Medicine and Cardiac Magnetic Resonance Imaging, which was held March 20-22,1991 in Rotterdam, the Netherlands. It covers almost every aspect of quantitative cardio-vascular nuclear medicine and magnetic resonance imaging. The main topics are: single photon emission computed tomography (technical aspects); new development in cardiovascular nuclear medicine; advances in cardiovascular imaging; cardiovascular clinical applications; and cardiac magnetic resonance imaging. (A.S.). refs.; figs.; tabs

  9. Developments in nuclear medicine

    International Nuclear Information System (INIS)

    Elias, H.

    1977-01-01

    The article reports on the first international meeting about radiopharmaceutical chemistry in the Brookhaven National Laboratory, Long Island/USA, from 21st to 24th September, 1976. The meeting report is preceded by the explanation of the terms 'radiopharmaceutical chemistry' and 'nuclear medicine' and a brief survey of the history. The interdisciplinary connection of the spheres of nuclear physics, nuclear chemistry, biochemistry, nuclear medicine, and data processing is also briefly shown. This is necessary before radiodiagnosis can be made for a patient. (RB) [de

  10. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... including many types of cancers, heart disease, gastrointestinal, endocrine, neurological disorders and other abnormalities within the body. ... Physicians use nuclear medicine imaging to evaluate organ systems, including the: kidneys and bladder. bones. liver and ...

  11. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... beforehand, especially if sedation is to be used. Most nuclear medicine exams will involve an injection in ... PET/CT, SPECT/CT and PET/MR) are most often used in children with cancer, epilepsy and ...

  12. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... small amount of energy in the form of gamma rays. Special cameras detect this energy, and with ... imaging techniques used in nuclear medicine include the gamma camera and single-photon emission-computed tomography (SPECT). ...

  13. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... to be followed after leaving the nuclear medicine facility. Through the natural process of radioactive decay, the ... Please note RadiologyInfo.org is not a medical facility. Please contact your physician with specific medical questions ...

  14. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... top of page What are the benefits vs. risks? Benefits The information provided by nuclear medicine examinations ... diagnosis or to determine appropriate treatment, if any. Risks Because the doses of radiotracer administered are small, ...

  15. Children's (Pediatric) Nuclear Medicine

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    Full Text Available ... of page How does the nuclear medicine procedure work? With ordinary x-ray examinations, an image is ... result, imaging may be done immediately, a few hours later, or even a few days after your ...

  16. Children's (Pediatric) Nuclear Medicine

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    Full Text Available ... exams at the same time. An emerging imaging technology, but not readily available at this time is ... leaving the nuclear medicine facility. Through the natural process of radioactive decay, the small amount of radiotracer ...

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    Full Text Available ... leaving the nuclear medicine facility. Through the natural process of radioactive decay, the small amount of radiotracer ... possible charges you will incur. Web page review process: This Web page is reviewed regularly by a ...

  18. Children's (Pediatric) Nuclear Medicine

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    Full Text Available ... of page How does the nuclear medicine procedure work? With ordinary x-ray examinations, an image is ... The exception to this is if the child’s mother is pregnant. When the examination is completed, your ...

  19. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... the most useful information needed to make a diagnosis or to determine appropriate treatment, if any. Risks Because the doses of radiotracer administered are small, diagnostic nuclear medicine procedures result in low radiation exposure, ...

  20. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... nuclear medicine images can be superimposed with computed tomography (CT) or magnetic resonance imaging (MRI) to produce ... manufacturers are now making single photon emission computed tomography/computed tomography (SPECT/CT) and positron emission tomography/ ...

  1. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... Because the doses of radiotracer administered are small, diagnostic nuclear medicine procedures result in low radiation exposure, acceptable for diagnostic exams. Thus, the radiation risk is very low ...

  2. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... molecular information. In many centers, nuclear medicine images can be superimposed with computed tomography (CT) or magnetic ... small hand-held device resembling a microphone that can detect and measure the amount of the radiotracer ...

  3. Tomography in nuclear medicine

    International Nuclear Information System (INIS)

    Levi de Cabrejas, Mariana

    1999-01-01

    This book is a contribution to the training and diffusion of the tomography method image diagnosis in nuclear medicine, which principal purpose is the information to professionals and technical personnel, specially for the spanish speaking staff

  4. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... both imaging exams at the same time. An emerging imaging technology, but not readily available at this ... often unattainable using other imaging procedures. For many diseases, nuclear medicine scans yield the most useful information ...

  5. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... endocrine, neurological disorders and other abnormalities within the body. Because nuclear medicine procedures are able to pinpoint molecular activity within the body, they offer the potential to identify disease in ...

  6. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... and are rarely associated with significant discomfort or side effects. If the radiotracer is given intravenously, your child ... techniques for a variety of indications, and the functional information gained from nuclear medicine exams is often ...

  7. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... to Children's (Pediatric) Nuclear Medicine Sponsored by Please note RadiologyInfo.org is not a medical facility. Please ... is further reviewed by committees from the American College of Radiology (ACR) and the Radiological Society of ...

  8. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... variety of diseases, including many types of cancers, heart disease, gastrointestinal, endocrine, neurological disorders and other abnormalities ... and bladder. bones. liver and gallbladder. gastrointestinal tract. heart. lungs. brain. thyroid. Nuclear medicine scans are typically ...

  9. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... bones. liver and gallbladder. gastrointestinal tract. heart. lungs. brain. thyroid. Nuclear medicine scans are typically used to ... differently than when breathing room air or holding his or her breath. With some exams, a catheter ...

  10. Children's (Pediatric) Nuclear Medicine

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    Full Text Available ... MRI. top of page What are some common uses of the procedure? Children's (pediatric) nuclear medicine imaging ... community, you can search the ACR-accredited facilities database . This website does not provide cost information. The ...

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    Full Text Available ... computer, create pictures offering details on both the structure and function of organs and tissues in your ... substantially shorten the procedure time. The resolution of structures of the body with nuclear medicine may not ...

  12. Children's (Pediatric) Nuclear Medicine

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    Full Text Available ... kidneys and bladder. bones. liver and gallbladder. gastrointestinal tract. heart. lungs. brain. thyroid. Nuclear medicine scans are typically used to help diagnose and evaluate: urinary blockage in the kidney. backflow of urine from ...

  13. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... exams at the same time. An emerging imaging technology, but not readily available at this time is PET/MRI. top of page What are some common uses of the procedure? Children's (pediatric) nuclear medicine imaging ...

  14. Children's (Pediatric) Nuclear Medicine

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  16. Children's (Pediatric) Nuclear Medicine

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    Full Text Available ... also very helpful. Often, a monitor with children's programming and/or children’s DVDs are available in the ... techniques for a variety of indications, and the functional information gained from nuclear medicine exams is often ...

  17. Children's (Pediatric) Nuclear Medicine

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  18. Children's (Pediatric) Nuclear Medicine

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    Full Text Available ... of page How does the nuclear medicine procedure work? With ordinary x-ray examinations, an image is ... than five decades, and there are no known long-term adverse effects from such low-dose exposure. ...

  19. Children's (Pediatric) Nuclear Medicine

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    Full Text Available ... exams at the same time. An emerging imaging technology, but not readily available at this time is ... bones. liver and gallbladder. gastrointestinal tract. heart. lungs. brain. thyroid. Nuclear medicine scans are typically used to ...

  20. Children's (Pediatric) Nuclear Medicine

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    Full Text Available ... performed to help diagnose childhood disorders that are congenital (present at birth) or that develop during childhood. ... often unattainable using other imaging procedures. For many diseases, nuclear medicine scans yield the most useful information ...

  1. Applications of extraction chromatography in the development of radionuclide generator systems for nuclear medicine

    International Nuclear Information System (INIS)

    Dietz, M.L.; Horwitz, E.P.

    2000-01-01

    Numerous methods have been described for the separation and purification of radionuclides for application in diagnostic and therapeutic nuclear medicine, among them ion exchange, solvent extraction, and various forms of chromatography. Although extraction chromatography has previously been shown to provide a means of performing a number of separations of potential use in radionuclide generator systems, the application of the technique to generator development has thus far been limited. Recent work directed at improved methods for the determination of radionuclides in biological and environmental samples has led to the development of a series of novel extraction chromatographic resins exhibiting enhanced metal ion retention from strongly acidic media and excellent selectivity, among them materials suitable for the isolation of 212 Bi, 90 Y, and 213 Bi. These resins, along with extraction chromatographic materials employing functionalized supports to improve their physical stability or metal ion retention properties, are shown to offer promise in the development of improved radionuclide generators

  2. The application of drug delivery system about nanoparticles in nuclear medicine

    International Nuclear Information System (INIS)

    Yao Ning; Wang Rongfu

    2013-01-01

    The development of nuclear medicine relies on the advancement of precise probes at the cellular and molecular levels. Nanoparticle as a new molecular probe, is mainly consists of the targeting groups, imaging groups, the superb biocompatible 'shells' and the modify groups. These nanoparticles have the better image contrast by targeting positioning in the target tissues and cells. At the same time, because of the diversity of the materials and the uniqueness of the structures, the nanoparticles can realize multimodal imaging at molecular level, which complement each other's advantages of different imaging modals. If the treatment groups are joined into the nanoparticles, a new nanoparticles are formed-the theranosis nanoparticles, which have realized the diagnosis and therapy at the molecular level synchronously. In addition, the application of intelligent nanoprobes can achieve the smart control of drug release and reduce the side effects of cancer treatment. Anyhow, the development of this new drug delivery system about nanoparticles has brought about a new breakthrough on the nuclear medicine. (authors)

  3. Nuclear medicine. 1 part. Manual

    International Nuclear Information System (INIS)

    Shlygina, O.E.; Borisenko, A.R.

    2006-01-01

    Current manual is urged to give wide-scale readers a submission on a key principles and methods of nuclear medicine, and it opportunities and restrictions in diagnostics and treatment of different diseases. Nuclear medicine is differing first of all by combination of diverse knowledge fields: special knowledge of a doctor, knowledge of physical processes bases, related with radiation, grounds of radiopharmaceutics, dosimetry. In the base of the book the 5th edition of 'Nuclear medicine' manual in 2 parts of German authors - Schicha, G.; Schober, O. is applied. In the book publishing the stuff of the Institute of Nuclear Physics of the National Nuclear Center of Republic of Kazakhstan has been worked. Modifications undergo practically all chapters: especially the second one, forth and sixth was enlarged. The 1 part of the book was published due to support of IAEA within the Technical cooperation project 'Implementation of Nuclear Medicine and Biophysics Center' (KAZ/6/007). The manual second part - devoted to applications of nuclear medicine methods for diagnostics and treatment - will be published in 2007

  4. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... radioactive energy that is emitted from the patient's body and converts it into an image. The gamma camera itself does not emit any ... bear denotes child-specific content. Related Articles and Media General Nuclear ... (Pediatric) Nuclear Medicine Videos related ...

  5. Experimental nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Dormehl, I C [Nuclear Development Corp. of South Africa (Pty.) Ltd., Pelindaba, Pretoria. Inst. of Life Sciences; Du Plessis, M; Jacobs, D J

    1983-07-01

    Exciting investigative research, widening the dimensions of conventional nuclear medicine, is being conducted in Pretoria where the development and evaluation of new radiopharmaceuticals in particular is attracting international attention. Additional to this, the development of new diagnostic techniques involving sophisticated data processing, is helping to place South Africa firmly in the front line of nuclear medical progress.

  6. Production and radioiodination of monoclonal antibodies and its applications in nuclear medicine

    International Nuclear Information System (INIS)

    Toledo e Souza, I.T. de; Okada, H.

    1988-12-01

    The basis of the monoclonal antibody production methodology, some immunological concepts which are important for the understanding of what is a Monoclonal Antibody, its radioiodination and acceptance as receptor-specific radiopharmaceuticals in nuclear medicine are reviewed. (author) [pt

  7. Clinical applications of SPECT/CT: New hybrid nuclear medicine imaging system

    International Nuclear Information System (INIS)

    2008-08-01

    Interest in multimodality imaging shows no sign of subsiding. New tracers are spreading out the spectrum of clinical applications and innovative technological solutions are preparing the way for yet more modality marriages: hybrid imaging. Single photon emission computed tomography (SPECT) has enabled the evaluation of disease processes based on functional and metabolic information of organs and cells. Integration of X ray computed tomography (CT) into SPECT has recently emerged as a brilliant diagnostic tool in medical imaging, where anatomical details may delineate functional and metabolic information. SPECT/CT has proven to be valuable in oncology. For example, in the case of a patient with metastatic thyroid cancer, neither SPECT nor CT alone could identify the site of malignancy. SPECT/CT, a hybrid image, precisely identified where the surgeon should operate. However SPECT/CT is not just advantageous in oncology. It may also be used as a one-stop-shop for various diseases. Clinical applications with SPECT/CT have started and expanded in developed countries. It has been reported that moving from SPECT alone to SPECT/CT could change diagnoses in 30% of cases. Large numbers of people could therefore benefit from this shift all over the world. This report presents an overview of clinical applications of SPECT/CT and a relevant source of information for nuclear medicine physicians, radiologists and clinical practitioners. This information may also be useful for decision making when allocating resources dedicated to the health care system, a critical issue that is especially important for the development of nuclear medicine in developing countries. In this regard, the IAEA may be heavily involved in the promotion of programmes aimed at the IAEA's coordinated research projects and Technical Cooperation projects

  8. Applications of Nuclear Physics

    OpenAIRE

    Hayes, Anna C.

    2017-01-01

    Today the applications of nuclear physics span a very broad range of topics and fields. This review discusses a number of aspects of these applications, including selected topics and concepts in nuclear reactor physics, nuclear fusion, nuclear non-proliferation, nuclear-geophysics, and nuclear medicine. The review begins with a historic summary of the early years in applied nuclear physics, with an emphasis on the huge developments that took place around the time of World War II, and that und...

  9. Knowledge Management in Nuclear Medicine

    International Nuclear Information System (INIS)

    Abaza, A.

    2017-01-01

    The last two decades have seen a significant increase in the demand for medical radiation services following the introduction of new techniques and technologies that has led to major improvements in the diagnosis and treatment of human diseases. The diagnostic and therapeutic applications of nuclear medicine techniques play a pivotal role in the management of these diseases, improving the quality of life of patients by means of an early diagnosis allowing opportune and proper therapy. On the other hand, inappropriate or unskilled use of these technologies can result in potential health hazards for patients and staff. So, there is a need to control and minimize these health risks and to maximize the benefits of radiation in medicine. The present study aims to discuss the role of nuclear medicine technology knowledge and scales in improving the management of patients, and raising the awareness and knowledge of nuclear medicine staff regarding the use of nuclear medicine facilities. The practical experience knowledge of nuclear medicine staff in 50 medical centers was reviewed through normal visiting and compared with the IAEA Published documents information. This review shows that the nuclear medicine staff has good technology knowledge and scales during managing patients as compared to IAEA Published information regarding the radiation protection measures and regulation. The outcome of the study reveals that competent authority can improve radiation safety in medical settings by developing and facilitating the implementation of scientific evidence-based policies and recommendations covering nuclear medicine technology focusing in the public health aspects and considering the risks and benefits of the use of radiation in health care. It could be concluded that concerted and coordinated efforts are required to improve radiation safety, quality and sustain ability of health systems

  10. Nuclear medicine resources manual

    International Nuclear Information System (INIS)

    2006-02-01

    Over the past decade many IAEA programmes have significantly enhanced the capabilities of numerous Member States in the field of nuclear medicine. Functional imaging using nuclear medicine procedures has become an indispensable tool for the diagnosis, treatment planning and management of patients. However, due to the heterogeneous growth and development of nuclear medicine in the IAEA's Member States, the operating standards of practice vary considerably from country to country and region to region. This publication is the result of the work of over 30 international professionals who have assisted the IAEA in the process of standardization and harmonization. This manual sets out the prerequisites for the establishment of a nuclear medicine service, including basic infrastructure, suitable premises, reliable supply of electricity, maintenance of a steady temperature, dust exclusion for gamma cameras and radiopharmacy dispensaries. It offers clear guidance on human resources and training needs for medical doctors, technologists, radiopharmaceutical scientists, physicists and specialist nurses in the practice of nuclear medicine. The manual describes the requirements for safe preparation and quality control of radiopharmaceuticals. In addition, it contains essential requirements for maintenance of facilities and instruments, for radiation hygiene and for optimization of nuclear medicine operational performance with the use of working clinical protocols. The result is a comprehensive guide at an international level that contains practical suggestions based on the experience of professionals around the globe. This publication will be of interest to nuclear medicine physicians, radiologists, medical educationalists, diagnostic centre managers, medical physicists, medical technologists, radiopharmacists, specialist nurses, clinical scientists and those engaged in quality assurance and control systems in public health in both developed and developing countries

  11. Nuclear Medicine Practice in Kenya

    International Nuclear Information System (INIS)

    Ndrirangu, T.T.

    2017-01-01

    Nuclear medicine is a medical specialty that relies on the use of nuclear technology in the diagnosis and treatment (therapy) of diseases. Nuclear medicine uses the principle that a certain radiopharmaceutical (tracer) will at a certain point in time have a preferential uptake by a particular body, tissue or cell. Unlike other radiation applications for medical use, nuclear medicine uses open (unsealed) sources of radiation. The tracer is introduced into the body of the patient through several routes (oral, intravenous, percutaneous, intradermally, inhalation, intracapsular etc) and s/he becomes the source of radiation. Early diagnosis of diseases coupled with associated timely therapeutic intervention will lead to better prognosis. In a country with an estimated population of 42 million in 2017, Kenya has only two (2) nuclear medicine facilities (units) that is Kenyatta National Hospital - Public facility and Aga Khan University Hospital which is a Private facility. Being a relatively new medical discipline in Kenya, several measures have been taken by the clinical nuclear medicine team to create awareness at various levels. Kenya does not manufacture radiopharmaceuticals. We therefore have to import them from abroad and this makes them quite expensive, and the process demanding. There is no local training in nuclear medicine and staff have to be sent abroad for training, making this quite expensive and cumbersome and the IAEA has been complimenting in this area. With concerted effort by all stakeholders at the individual, national and international level, it is possible for Kenya to effectively sustain clinical nuclear medicine service not only as a diagnostic tool in many disease entities, but also play an increasingly important role in therapy

  12. Nuclear Medicine Engineering

    International Nuclear Information System (INIS)

    Mateescu, Gheorghe; Craciunescu, Teddy

    2000-01-01

    'An image is more valuable than a thousand words' - this is the thought that underlies the authors' vision about the field of nuclear medicine. The monograph starts with a review of some theoretical and engineering notions that grounds the field of nuclear medicine: nuclear radiation, interaction of radiation with matter, radiation detection and measurement, numerical analysis. Products and methods needed for the implementation of diagnostic and research procedures in nuclear medicine are presented: radioisotopes and radiopharmaceuticals, equipment for in-vitro (radioimmunoassay, liquid scintillation counting) and in-vivo investigations (thyroid uptake, renography, dynamic studies, imaging). A special attention is focused on medical imaging theory and practice as a source of clinical information (morphological and functional). The large variety of parameters, components, biological structures and specific properties of live matter determines the practical use of three-dimensional tomographic techniques based on diverse physical principles: single-photon emission, positron emission, X-rays transmission, nuclear magnetic resonance, ultrasounds transmission and reflection, electrical impedance measurement. The fundamental reconstruction algorithms i.e., algorithms based on the projection theorem and Fourier filtering, algebraic reconstruction techniques and the algorithms based on statistical principles: maximum entropy, maximum likelihood, Monte Carlo algorithms, are depicted in details. A method based on the use of the measured point spread function is suggested. Some classical but often used techniques like linear scintigraphy and Anger gamma camera imaging are also presented together with some image enhancement techniques like Wiener filtering and blind deconvolution. The topic of the book is illustrated with some clinical samples obtained with nuclear medicine devices developed in the Nuclear Medicine Laboratory of the National Institute of Nuclear Physics and

  13. Nuclear tele medicine

    International Nuclear Information System (INIS)

    Vargas, L.; Hernandez, F.; Fernandez, R.

    2005-01-01

    The great majority of the digital images of nuclear medicine are susceptible of being sent through internet. This has allowed that the work in diagnosis cabinets by image it can benefit of this modern technology. We have presented in previous congresses works related with tele medicine, however, due to the speed in the evolution of the computer programs and the internet, becomes necessary to make a current position in this modality of work. (Author)

  14. Prospects for the applications of computer in the field of domestic nuclear medicinal instrument

    International Nuclear Information System (INIS)

    Zhao Changhe

    1993-01-01

    The current situation and prospects about domestic nuclear medical instrument, as well as the comparisons of computer application in nuclear medical instruments with in other medical instruments from various points of view have all been described in the paper

  15. Paediatric nuclear medicine imaging.

    Science.gov (United States)

    Biassoni, Lorenzo; Easty, Marina

    2017-09-01

    Nuclear medicine imaging explores tissue viability and function by using radiotracers that are taken up at cellular level with different mechanism. This imaging technique can also be used to assess blood flow and transit through tubular organs. Nuclear medicine imaging has been used in paediatrics for decades and this field is continuously evolving. The data presented comes from clinical experience and some milestone papers on the subject. Nuclear medicine imaging is well-established in paediatric nephro-urology in the context of urinary tract infection, ante-natally diagnosed hydronephrosis and other congenital renal anomalies. Also, in paediatric oncology, I-123-meta-iodobenzyl-guanidine has a key role in the management of children with neuroblastic tumours. Bone scintigraphy is still highly valuable to localize the source of symptoms in children and adolescents with bone pain when other imaging techniques have failed. Thyroid scintigraphy in neonates with congenital hypothyroidism is the most accurate imaging technique to confirm the presence of ectopic functioning thyroid tissue. Radionuclide transit studies of the gastro-intestinal tract are potentially useful in suspected gastroparesis or small bowel or colonic dysmotility. However, until now a standardized protocol and a validated normal range have not been agreed, and more work is necessary. Research is ongoing on whether magnetic resonance imaging (MRI), with its great advantage of great anatomical detail and no ionizing radiations, can replace nuclear medicine imaging in some clinical context. On the other hand, access to MRI is often difficult in many district general hospitals and general anaesthesia is frequently required, thus adding to the complexity of the examination. Patients with bone pain and no cause for it demonstrated on MRI can benefit from bone scintigraphy with single photon emission tomography and low-dose computed tomography. This technique can identify areas of mechanical stress at

  16. Physics in nuclear medicine

    CERN Document Server

    Cherry, Simon R; Phelps, Michael E

    2012-01-01

    Physics in Nuclear Medicine - by Drs. Simon R. Cherry, James A. Sorenson, and Michael E. Phelps - provides current, comprehensive guidance on the physics underlying modern nuclear medicine and imaging using radioactively labeled tracers. This revised and updated fourth edition features a new full-color layout, as well as the latest information on instrumentation and technology. Stay current on crucial developments in hybrid imaging (PET/CT and SPECT/CT), and small animal imaging, and benefit from the new section on tracer kinetic modeling in neuroreceptor imaging.

  17. Children in nuclear medicine

    International Nuclear Information System (INIS)

    Fischer, S.

    2002-01-01

    With each study in paediatric nuclear medicine one must try to reach a high quality standard with a minimum of radiation exposure to the child. This is true for the indication for the study and the interpretation of the results as well as the preparation, the image acquisition, the processing and the documentation. A continuous evaluation of all aspects is necessary to receive optimal, clinically relevant information. In addition it is important that the child keeps nuclear medicine in a good mind, especially when it has to come back for a control study. (orig.) [de

  18. Radiation physics for nuclear medicine

    CERN Document Server

    Hoeschen, Christoph

    2011-01-01

    The field of nuclear medicine is expanding rapidly, with the development of exciting new diagnostic methods and treatments. This growth is closely associated with significant advances in radiation physics. In this book, acknowledged experts explain the basic principles of radiation physics in relation to nuclear medicine and examine important novel approaches in the field. The first section is devoted to what might be termed the "building blocks" of nuclear medicine, including the mechanisms of interaction between radiation and matter and Monte Carlo codes. In subsequent sections, radiation sources for medical applications, radiopharmaceutical development and production, and radiation detectors are discussed in detail. New frontiers are then explored, including improved algorithms for image reconstruction, biokinetic models, and voxel phantoms for internal dosimetry. Both trainees and experienced practitioners and researchers will find this book to be an invaluable source of up-to-date information.

  19. Nuclear medicine in China

    International Nuclear Information System (INIS)

    Wang, Shihchen; Liu, Xiujie

    1986-01-01

    Since China first applied isotopes to medical research in 1956, over 800 hospitals and research institutions with 4000 staff have taken up nuclear technology. So far, over 120 important biologically active materials have been measured by radioimmunoassay in China, and 44 types of RIA kit have been supplied commercially. More than 50,000 cases of hyperthyroidism have been treated satisfactorily with 131 I. Radionuclide imaging of practically all organs and systems of the human body has been performed, and adrenal imaging and nuclear cardiology have become routine clinical practice in several large hospitals. The thyroid iodine uptake test, renogram tracing and cardiac function studies with a cardiac probe are also commonly used in most Chinese hospitals. The active principles of more than 60 medicinal herbs have been labelled with isotopes in order to study the drug metabolism and mechanism of action. Through the use of labelled neurotransmitters or deoxyglucose, RIA, radioreceptor assay and autoradiography, Chinese researchers have made remarkable achievements in the study of the scientific basis of acupuncture analgesia. In 1980 the Chinese Society of Nuclear Medicine was founded, and since 1981 the Chinese Journal of Nuclear Medicine has been published. Although nuclear medicine in China has already made some progress, when compared with advanced countries, much progress is still to be made. It is hoped that international scientific exchange will be strengthened in the future. (author)

  20. Computers in nuclear medicine: introductory concepts

    International Nuclear Information System (INIS)

    Weber, D.A.

    1978-01-01

    Computers play an important role in image and data processing in nuclear medicine. Applications extend from relatively simple mathematical processing of in vitro specimen assays to more sophisticated image reconstruction procedures for emission tomography. The basic concepts and terminology associated with computer applications in image and data processing in nuclear medicine are presented here

  1. Technetium-99m: From nuclear medicine applications to fine sediment transport studies

    Directory of Open Access Journals (Sweden)

    Bandeira Jefferson V.

    2017-12-01

    Full Text Available The present work is a contribution to rescue the history of development of the application of 99mTc, widely used in nuclear medicine, to its use as tracer for the study of the transport of fine sediment in suspension, in water environment. It addresses the usefulness of its application in obtaining important parameters in environmental studies, illustrating them with some applications already performed and the results obtained. This kind of study, when associated with information on hydrodynamic parameters, for example, river, tidal, wind and wave currents, are powerful tools for the understanding and quantification of fine sediment transport in suspension. Fine sediment is an important vector in the transportation of heavy metals, organic matter and nutrients in water environment, and the quantitative knowledge of its behaviour is mandatory for studies of environmental impacts. Fine sediment labelled with 99mTc, can also be used to study the effect of human interventions, such as dredging of reservoirs, access channels and harbours, and the dumping of dredged materials in water bodies. Besides that, it can be used to optimize dredging works, evaluating the technical and economic feasibility of dumping sites and their environmental impact. It is a valuable support in the calibration and validation of mathematical models for sediment dynamics.

  2. Applications of nuclear physics

    Science.gov (United States)

    Hayes, A. C.

    2017-02-01

    Today the applications of nuclear physics span a very broad range of topics and fields. This review discusses a number of aspects of these applications, including selected topics and concepts in nuclear reactor physics, nuclear fusion, nuclear non-proliferation, nuclear-geophysics, and nuclear medicine. The review begins with a historic summary of the early years in applied nuclear physics, with an emphasis on the huge developments that took place around the time of World War II, and that underlie the physics involved in designs of nuclear explosions, controlled nuclear energy, and nuclear fusion. The review then moves to focus on modern applications of these concepts, including the basic concepts and diagnostics developed for the forensics of nuclear explosions, the nuclear diagnostics at the National Ignition Facility, nuclear reactor safeguards, and the detection of nuclear material production and trafficking. The review also summarizes recent developments in nuclear geophysics and nuclear medicine. The nuclear geophysics areas discussed include geo-chronology, nuclear logging for industry, the Oklo reactor, and geo-neutrinos. The section on nuclear medicine summarizes the critical advances in nuclear imaging, including PET and SPECT imaging, targeted radionuclide therapy, and the nuclear physics of medical isotope production. Each subfield discussed requires a review article unto itself, which is not the intention of the current review; rather, the current review is intended for readers who wish to get a broad understanding of applied nuclear physics.

  3. Applications of nuclear physics

    International Nuclear Information System (INIS)

    Hayes-Sterbenz, Anna Catherine

    2017-01-01

    Today the applications of nuclear physics span a very broad range of topics and fields. This review discusses a number of aspects of these applications, including selected topics and concepts in nuclear reactor physics, nuclear fusion, nuclear non-proliferation, nuclear-geophysics, and nuclear medicine. The review begins with a historic summary of the early years in applied nuclear physics, with an emphasis on the huge developments that took place around the time of World War II, and that underlie the physics involved in designs of nuclear explosions, controlled nuclear energy, and nuclear fusion. The review then moves to focus on modern applications of these concepts, including the basic concepts and diagnostics developed for the forensics of nuclear explosions, the nuclear diagnostics at the National Ignition Facility, nuclear reactor safeguards, and the detection of nuclear material production and trafficking. The review also summarizes recent developments in nuclear geophysics and nuclear medicine. The nuclear geophysics areas discussed include geo-chronology, nuclear logging for industry, the Oklo reactor, and geo-neutrinos. The section on nuclear medicine summarizes the critical advances in nuclear imaging, including PET and SPECT imaging, targeted radionuclide therapy, and the nuclear physics of medical isotope production. Lastly, each subfield discussed requires a review article unto itself, which is not the intention of the current review; rather, the current review is intended for readers who wish to get a broad understanding of applied nuclear physics.

  4. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available Toggle navigation Test/Treatment Patient Type Screening/Wellness Disease/Condition Safety En Español More Info Images/Videos About Us News Physician Resources Professions Site Index A-Z Children's (Pediatric) Nuclear Medicine ...

  5. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... measure the amount of the radiotracer in a small area of your child's body. top of page How is the procedure performed? Nuclear medicine imaging is usually performed on an ... Intravenous: a small needle is used to inject the radiotracer. The ...

  6. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... diagnoses. In addition, manufacturers are now making single photon emission computed tomography/computed tomography (SPECT/CT) and ... nuclear medicine include the gamma camera and single-photon emission-computed tomography (SPECT). The gamma camera, also ...

  7. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... The special camera and imaging techniques used in nuclear medicine include the gamma camera and single-photon emission-computed tomography (SPECT). The gamma camera, also called a scintillation camera, detects radioactive energy that is emitted from the patient's body and ...

  8. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... Pediatric) Nuclear Medicine Sponsored by Please note RadiologyInfo.org is not a medical facility. Please contact your ... links: For the convenience of our users, RadiologyInfo .org provides links to relevant websites. RadiologyInfo.org , ACR ...

  9. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... exams at the same time. An emerging imaging technology, but not readily available at this time is PET/MRI. top of page What are some common uses of the procedure? Children's (pediatric) nuclear medicine imaging is performed to help ...

  10. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... both imaging exams at the same time. An emerging imaging technology, but not readily available at this time is PET/MRI. top of page What are some common uses of the procedure? Children's (pediatric) nuclear medicine imaging is performed to help diagnose childhood disorders ...

  11. More about ... Nuclear medicine

    African Journals Online (AJOL)

    Thyroid scintigraphy. In neonates with hypothyroidism detected on neonatal screening and confirmed by subsequent testing, a radionuclide thyroid scan should be performed as soon as possible. It must be undertaken in all nuclear medicine departments as a matter of urgency. Any delay in treatment should be avoided.

  12. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... nuclear medicine images can be superimposed with computed tomography (CT) or magnetic resonance imaging (MRI) to produce special ... now making single photon emission computed tomography/computed tomography (SPECT/CT) and positron emission tomography/computed tomography (PET/CT) ...

  13. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... drink before the exam, especially if your physician plans to use sedation for the procedure. top of page Who interprets the results and how do we get them? A radiologist or other physician who has specialized training in nuclear medicine will interpret the images and ...

  14. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... pictures and provides molecular information. In many centers, nuclear medicine images can be superimposed with computed tomography (CT) or magnetic resonance imaging (MRI) to produce special views, a practice known as image fusion or co-registration. These views allow the information ...

  15. Application of medical psychology in the reception of nuclear medicine department

    International Nuclear Information System (INIS)

    Zhan Hao; Xiong Jie; Huang Daijuan; Yuan Bin; Xu Wendai; Zhang Yongxue

    2003-01-01

    Reception of nuclear medicine department is often ignored. In fact, it is an important part of clinical work. If the patient's psychological status is understood, and the psychological knowledge is handles and applied in practice, the quality of work can be improved. The personnel in nuclear medicine should recognize the significance of humanity in medical practice and acquire the communication skill between doctors and patients. They should also understand the four aspects of psychological need of patients: The need of being understood and respected; the need of being greeted, accepted and a sense of belonging; the need of being informed; the need of feeling safe and rehabilitated

  16. Promoting nuclear medicine in developing countries

    International Nuclear Information System (INIS)

    Ganatra, R.; Nofal, M.

    1986-01-01

    After a short review of the applications of nuclear medicine in diagnosis and treatment of diseases or in medical research the ways and the means of IAEA's support in helping developing countries to set up nuclear medicine capabilities in their hospitals are described. Some trends and new directions in the field of nuclear medicine and the problems related to the implementation of these techniques in developing countries are presented

  17. Nuclear medicine. Basic knowledge and clinical applications. 6. rev. and upd. ed.

    International Nuclear Information System (INIS)

    Schicha, H.; Schober, O.

    2007-01-01

    The development of imaging techniques like SPECT, SPECT-CT, PET, PET-CT and MRT has advanced rapidly during the past few years, especially in the case of hybrid technology. These techniques have become indispensable in diagnosis, differential diagnosis, therapy follow-up and prevention. This 6th revised and edited version of 'Nuclear Medicine' takes account of these developments. The general section presents fundamentals of physics, radiopharmaceutical chemistry, measuring techniques, nuclear medical examination techniques, and dosimetry. The special section presents detailed descriptions of all relevant nuclear medical techniques by organ systems and clinical pictures. There are many examples and scintiscans of organs to train the diagnostic eye and give a link to clinical practice. This successful textbook presents complex subject matter in a clear and intelligible way. It addresses newcomers and expert doctors that require training in nuclear medical methods. It has also become a standard textbook in university medicine studies and in the training of radiological assistants. (orig.)

  18. The development of new radionuclide generator systems for nuclear medicine applications

    International Nuclear Information System (INIS)

    Knapp, F.F. Jr.; Callahan, A.P.; Mirzadeh, S.; Brihaye, C.; Guillaume, M.

    1991-01-01

    Radioisotope generator systems have traditionally played a central role in nuclear medicine in providing radioisotopes for both research and clinical applications. In this paper, the development of several tungsten-188/rhenium-188 prototype generators which provide rhenium-188 for radioimmunotherapy (RAIT) is discussed. The authors have recently demonstrated that carrier-free iridium-194 can be obtained from the activated carbon system from decay of reactor-produced osmium-194 for potential RAIT applications. Instrumentation advances such as the new generation of high-count-rate (fast) gamma camera systems for first-pass technology require the availability of generator-produced ultra short-lived radioisotopes for radionuclide angiography (RNA). The activated carbon generator is an efficient system to obtain ultra short-lived iridium-191 m from osmium-191 for RNA. In addition, the growing number of PET centers has stimulated research in generators which provide positron-emitting radioisotopes. Copper-62, obtained from the zinc-62 generator, is currently used for PET evaluation of organ perfusion. The availability of the parent radioisotopes, the fabrication and use of these generators, and the practical factors for use of these systems in the radiopharmacy are discussed. 74 refs., 6 figs., 5 tabs

  19. Synthesis, evaluation and application of radioiodine labeled compounds in nuclear medicine

    International Nuclear Information System (INIS)

    Ahmed, M. O. M.

    2006-01-01

    This study reviews synthesis, evaluation,diagnostic and therapeutic applications of iodine radiopharmaceutical especially with 13I I and 123 I in contemporary nuclear medicine. It is well Known that iodine is used in thyroid diagnostic and therapy with sodium iodide and played an important role in diagnostic procedures using single photon emission tomography (SPECT). The study covers the general chemistry of iodine, physical properties, biological role of iodine, general uses of iodine compounds , production and decay schemes of 131 I, 125 I and 123 I in the first chapter. Preparation of radioiodine labeled compounds, quality control of radiopharmaceuticals and safety of radioiodination are dealt with in detail in two chapters. These were followed by chapters dealing in length with the chemistry, preparation, quality control, pharmacokinetics and radiation dosimetry of some iodine radiopharmaceuticals, and then current trends in diagnostic and therapeutic applications of iodine radiopharmaceuticals particularly 131 / 123 I-MIBG and 123 I-IMP. We found that the iodine radiopharmaceuticals are considered amongst principal indicators in single photon emission tomography (SPECT), and 131 / 123 I-MIBG and 123 I-IMP appear to be appropriate diagnostic and therapeutic agents for variety of diseases.(Author)

  20. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... you about nuclear medicine. Nuclear medicine offers the potential to identify disease in its earliest stage, often ... may be asked to wear a gown as well. Tell your doctor if there is any possibility ...

  1. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... Nuclear Medicine Transcript Welcome to Radiology Info dot org Hello! I’m Dr. Ramji Rajendran, a radiation ... more about nuclear medicine, visit Radiology Info dot org. Thank you for your time! Spotlight Recently posted: ...

  2. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... stage, often before symptoms occur or before abnormalities can be detected with other diagnostic tests. Nuclear medicine ... nuclear medicine exam, there are several things you can do to prepare. First, you may be asked ...

  3. Nuclear medicine technology study guide

    CERN Document Server

    Patel, Dee

    2011-01-01

    Nuclear Medicine Technology Study Guide presents a comprehensive review of nuclear medicine principles and concepts necessary for technologists to pass board examinations. The practice questions and content follow the guidelines of the Nuclear Medicine Technology Certification Board (NMTCB) and American Registry of Radiological Technologists (ARRT), allowing test takers to maximize their success in passing the examinations. The book is organized by sections of increasing difficulty, with over 600 multiple-choice questions covering all areas of nuclear medicine, including radiation safety; radi

  4. Nuclear medicine in sports

    International Nuclear Information System (INIS)

    Sharma, Anshu Rajnish

    2010-01-01

    Nuclear medicine can synergistically contribute to the sports medicine field, in the management of sports-related stress injures. Bone scintigraphy is commonly requested for evaluation of athletes with pain. Three-Phase 99m Tc MDP Bone Scan has emerged as the imaging reference standard for diagnosing such injuries. The inherently high-contrast resolution of the bone scan allows early detection of bone trauma and becomes positive within six to seventy-two hours after the onset of symptoms. The bone scan is able to demonstrate stress injuries days to weeks before the radiograph

  5. Quality control in nuclear medicine

    International Nuclear Information System (INIS)

    Leme, P.R.

    1983-01-01

    The following topics are discussed: objectives of the quality control in nuclear medicine; the necessity of the quality control in nuclear medicine; guidelines and recommendations. An appendix is given concerning the guidelines for the quality control and instrumentation in nuclear medicine. (M.A.) [pt

  6. Defining user requirements for tele-nuclear medicine applications: from technical feasibility to clinical results

    International Nuclear Information System (INIS)

    Todd-Pokropek, A.; Chanachai, R.

    2002-01-01

    Purpose: Defining the user requirements for tele-nuclear medicine systems, in particular in developing countries, is an important prerequisite to establishing a service. However, the availability of low cost PC based servers and, now, access to local ISPs, has made the technical provision of such networks relatively simple and low cost, although transfer of data to and form legacy systems still present many difficulties. Method and Materials: The key driving force in developing countries is the imbalance between skills in the relatively few centres of excellence and the increasing number of installations overall. Requirements include both very rapid remote reporting and/or overnight tele-consultation. Original raw NM data must be available not just 'images'. Using current network standards (VPN) data transfer rate requirements are low. Provision of image fusion between NM, CT and MRI is also highly desirable. Results: Experience has been obtained e.g. in Thailand and Morocco, where a network of servers and remote users, with cardiac application of particular importance, has demonstrated benefit, and increasing volumes of usage. Conclusions: However, the requirements need to be clearly defined, and a staff training program is essential, as is a full evaluation. The transfer of skills is important in raising the overall quality of health care

  7. Introduction to nuclear medicine

    International Nuclear Information System (INIS)

    Denhartog, P.; Wilmot, D.M.

    1987-01-01

    In this chapter, the fundamentals of nuclear medicine, the advantages and disadvantages of this modality (compared with radiography and ultrasound), and some of the areas in diagnosis and treatment in which it has found widest acceptance will be discussed. Nuclear medicine procedures can be broadly categorized into three groups: in vivo imaging, usually requiring the injection of an organ-specific radiopharmaceutical; in vitro procedures, in which the radioactive agent is mixed with the patient's blood in a test tube; and in vivo nonimaging procedures, in which the patient receives the radiopharmaceutical (intravenously or orally) after which a measurement of the amount appearing in a particular biological specimen (blood, urine, stool) is performed. In vivo imaging procedures will be the principal topics of this chapter

  8. Nuclear medicine in otolaryngology

    International Nuclear Information System (INIS)

    Watkinson, J.C.

    1991-01-01

    Otolaryngology is concerned with the diagnosis and treatment of diseases which affect the mucosal structures of the upper aerodigestive tract and adnexial organs. This editorial outlines the current rate of nuclear medicine in otolaryngology with particular reference to diseases of the thyroid, the parathyroid, the salivary glands, the lacrimal glands, bones of the head and neck, tumours of the head and neck and CSF leaks. (UK)

  9. Nuclear medicine therapy

    CERN Document Server

    Eary, Janet F

    2013-01-01

    One in three of the 30 million Americans who are hospitalized are diagnosed or treated with nuclear medicine techniques. This text provides a succinct overview and detailed set of procedures and considerations for patient therapy with unsealed radioactivity sources.  Serving as a complete literature reference for therapy with radiopharmaceuticals currently utilized in practice, this source covers the role of the physician in radionuclide therapy, and essential procedures and protocols required by health care personnel.

  10. Physical bases of nuclear medicine

    International Nuclear Information System (INIS)

    Isabelle, D.B.; Ducassou, D.

    1975-01-01

    The physical bases of nuclear medicine are outlined in several chapters devoted successively to: atomic and nuclear structures; nuclear reactions; radioactiity laws; a study of different types of disintegration; the interactions of radiations with matter [fr

  11. Computers in nuclear medicine

    International Nuclear Information System (INIS)

    Cradduck, T.D.; Knowles, L.G.

    1977-01-01

    The decision to buy a computer is difficult. The wide variety of computing systems available makes that decision even harder because each of the systems has unique advantages and disadvantages. The following list contains many of the essentials any computer system for nuclear medicine should embody: (1) sophisticated and reliable hardware with sufficient memory capacity to acquire or display at least 128 x 128 static images or 64 x 64 dynamic studies and with the facility for adding extra hardware and peripheral equipment at a later date; (2) a well-proved, general-purpose, real-time operating system to which the programs specific to the gamma camera have been interfaced and which will allow expansion or modification of both hardware and software in the future; (3) a display exhibiting at least 128 x 128 resolution, a monochrome mode with extended gray scale, and perhaps color; a varied set of programmed image formats and hardware system that includes local refresher capabilities; (4) a high-level language, such as FORTRAN or BASIC, with the ability to directly access all data files and interact with system programs as well as a macroprogramming capability so the user may write his own programs for data manipulation and analysis; (5) a comprehensive yet generally applicable set of system programs to enable data acquisition, storage, analysis, and display. In addition to the above, one should expect the services of a team of well-trained maintenance technicians and engineers. The manufacturer should offer software support and exhibit a plan for continued development and upgrading of the software initially provided

  12. Application for internal dosimetry using biokinetic distribution of photons based on nuclear medicine images.

    Science.gov (United States)

    Leal Neto, Viriato; Vieira, José Wilson; Lima, Fernando Roberto de Andrade

    2014-01-01

    This article presents a way to obtain estimates of dose in patients submitted to radiotherapy with basis on the analysis of regions of interest on nuclear medicine images. A software called DoRadIo (Dosimetria das Radiações Ionizantes [Ionizing Radiation Dosimetry]) was developed to receive information about source organs and target organs, generating graphical and numerical results. The nuclear medicine images utilized in the present study were obtained from catalogs provided by medical physicists. The simulations were performed with computational exposure models consisting of voxel phantoms coupled with the Monte Carlo EGSnrc code. The software was developed with the Microsoft Visual Studio 2010 Service Pack and the project template Windows Presentation Foundation for C# programming language. With the mentioned tools, the authors obtained the file for optimization of Monte Carlo simulations using the EGSnrc; organization and compaction of dosimetry results with all radioactive sources; selection of regions of interest; evaluation of grayscale intensity in regions of interest; the file of weighted sources; and, finally, all the charts and numerical results. The user interface may be adapted for use in clinical nuclear medicine as a computer-aided tool to estimate the administered activity.

  13. Application for internal dosimetry using biokinetic distribution of photons based on nuclear medicine images*

    Science.gov (United States)

    Leal Neto, Viriato; Vieira, José Wilson; Lima, Fernando Roberto de Andrade

    2014-01-01

    Objective This article presents a way to obtain estimates of dose in patients submitted to radiotherapy with basis on the analysis of regions of interest on nuclear medicine images. Materials and Methods A software called DoRadIo (Dosimetria das Radiações Ionizantes [Ionizing Radiation Dosimetry]) was developed to receive information about source organs and target organs, generating graphical and numerical results. The nuclear medicine images utilized in the present study were obtained from catalogs provided by medical physicists. The simulations were performed with computational exposure models consisting of voxel phantoms coupled with the Monte Carlo EGSnrc code. The software was developed with the Microsoft Visual Studio 2010 Service Pack and the project template Windows Presentation Foundation for C# programming language. Results With the mentioned tools, the authors obtained the file for optimization of Monte Carlo simulations using the EGSnrc; organization and compaction of dosimetry results with all radioactive sources; selection of regions of interest; evaluation of grayscale intensity in regions of interest; the file of weighted sources; and, finally, all the charts and numerical results. Conclusion The user interface may be adapted for use in clinical nuclear medicine as a computer-aided tool to estimate the administered activity. PMID:25741101

  14. Application for internal dosimetry using biokinetic distribution of photons based on nuclear medicine images

    International Nuclear Information System (INIS)

    Leal Neto, Viriato; Vieira, Jose Wilson; Lima, Fernando Roberto de Andrade

    2014-01-01

    Objective: this article presents a way to obtain estimates of dose in patients submitted to radiotherapy with basis on the analysis of regions of interest on nuclear medicine images. Materials and methods: a software called DoRadIo (Dosimetria das Radiacoes Ionizantes [Ionizing Radiation Dosimetry]) was developed to receive information about source organs and target organs, generating graphical and numerical results. The nuclear medicine images utilized in the present study were obtained from catalogs provided by medical physicists. The simulations were performed with computational exposure models consisting of voxel phantoms coupled with the Monte Carlo EGSnrc code. The software was developed with the Microsoft Visual Studio 2010 Service Pack and the project template Windows Presentation Foundation for C ⧣ programming language. Results: with the mentioned tools, the authors obtained the file for optimization of Monte Carlo simulations using the EGSnrc; organization and compaction of dosimetry results with all radioactive sources; selection of regions of interest; evaluation of grayscale intensity in regions of interest; the file of weighted sources; and, finally, all the charts and numerical results. Conclusion: the user interface may be adapted for use in clinical nuclear medicine as a computer-aided tool to estimate the administered activity. (author)

  15. Application for internal dosimetry using biokinetic distribution of photons based on nuclear medicine images

    Energy Technology Data Exchange (ETDEWEB)

    Leal Neto, Viriato, E-mail: viriatoleal@yahoo.com.br [Instituto Federal de Educacao, Ciencia e Tecnologia de Pernambuco (IFPE), Recife, PE (Brazil); Vieira, Jose Wilson [Universidade Federal de Pernambuco (UPE), Recife, PE (Brazil); Lima, Fernando Roberto de Andrade [Centro Regional de Ciencias Nucleares (CRCN-NE/CNEN-PE), Recife, PE (Brazil)

    2014-09-15

    Objective: this article presents a way to obtain estimates of dose in patients submitted to radiotherapy with basis on the analysis of regions of interest on nuclear medicine images. Materials and methods: a software called DoRadIo (Dosimetria das Radiacoes Ionizantes [Ionizing Radiation Dosimetry]) was developed to receive information about source organs and target organs, generating graphical and numerical results. The nuclear medicine images utilized in the present study were obtained from catalogs provided by medical physicists. The simulations were performed with computational exposure models consisting of voxel phantoms coupled with the Monte Carlo EGSnrc code. The software was developed with the Microsoft Visual Studio 2010 Service Pack and the project template Windows Presentation Foundation for C ⧣ programming language. Results: with the mentioned tools, the authors obtained the file for optimization of Monte Carlo simulations using the EGSnrc; organization and compaction of dosimetry results with all radioactive sources; selection of regions of interest; evaluation of grayscale intensity in regions of interest; the file of weighted sources; and, finally, all the charts and numerical results. Conclusion: the user interface may be adapted for use in clinical nuclear medicine as a computer-aided tool to estimate the administered activity. (author)

  16. Radioiodination and Bio evaluation of Some Cardiovascular Drugs for Nuclear Medicine Application

    International Nuclear Information System (INIS)

    El-Sharawy, D.M.M.

    2013-01-01

    Nuclear medicine specialists use safe, painless, and cost-effective techniques to image the body and treat disease. Nuclear medicine imaging is unique, because it provides doctors with information about both structure and function. It is a way to gather medical information that would otherwise be unavailable, require surgery, or necessitate more expensive diagnostic tests. Today, nuclear medicine offers procedures that are essential in many medical specialties, from pediatrics to cardiology to psychiatry. Radiopharmacy is the science that deals largely with the preparation, compounding, Quality Control (QC), and dispensing of radiopharmaceuticals and radioisotopes for human use. Radio pharmacists are the personnel who perform these functions at large hospitals or medical centers. They are involved in manufacturing cold kits and in developing new agents and procedures. In this thesis it was studied the labeling of Deltiazem , Nefidipine and Valsartan with iodine -125 via an electrophilic substitution reaction. The biological distribution of these tracers were studied and was found the possibility of their use in cardiovascular disorders.

  17. Frontiers in nuclear medicine symposium: Nuclear medicine & molecular biology

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-04-01

    This document contains the abstracts from the American College of Nuclear Physicians 1993 Fall Meeting entitled, `Frontiers in Nuclear Medicine Symposium: Nuclear Medicine and Molecular Biology`. This meeting was sponsored by the US DOE, Office of Health and Environmental Research, Office of Energy Research. The program chairman was Richard C. Reba, M.D.

  18. Neutron use in nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Guidez, J.; May, R.; Moss, R. [HFR-Unit, European Commission, IAM, Petten (Netherlands); Askienazy, S. [Departement Central de Medicine Nucleaire et Biophysique, Saint Antoine Hospital, Paris (France); Hildebrand, J. [Neurology Department, Erasmus Hospital, Brussels (Belgium)

    1999-07-01

    Neutrons produced by research reactors are being used in nuclear medicine and other medical applications in several ways. The High Flux Reactor (HFR) based in Petten (The Netherlands), owned by the European Commission, has been working increasingly in this field of health care for the European citizen. On the basis of this experience, a survey has been carried out on the main possibilities of neutrons used in nuclear medicine. The most important and most well known is the production of radioisotopes for diagnosis and therapy. Ten million patients receive nuclear medicine in Europe each year, with more than 8 million made with the products issued from research reactors. The survey of the market and the techniques (cyclotron, PET) shows that this market will continue to increase in the future. The direct use of reactors in medicine is actually made by the Boron Neutron capture Therapy (BNCT) for the treatment of glioblastoma, which kills about 15.000 people in Europe each year. For this promising technique, HFR is the most advanced for experimental possibilities and treatment studies. Medical research is also made in other promising fields: the use beam tubes for characterizing of prostheses and bio-medical materials, alpha-immuno therapy products, new types of radioisotopes, new types of illness to be treated by BNCT, etc. (author)

  19. Neutron use in nuclear medicine

    International Nuclear Information System (INIS)

    Guidez, J.; May, R.; Moss, R.; Askienazy, S.; Hildebrand, J.

    1999-01-01

    Neutrons produced by research reactors are being used in nuclear medicine and other medical applications in several ways. The High Flux Reactor (HFR) based in Petten (The Netherlands), owned by the European Commission, has been working increasingly in this field of health care for the European citizen. On the basis of this experience, a survey has been carried out on the main possibilities of neutrons used in nuclear medicine. The most important and most well known is the production of radioisotopes for diagnosis and therapy. Ten million patients receive nuclear medicine in Europe each year, with more than 8 million made with the products issued from research reactors. The survey of the market and the techniques (cyclotron, PET) shows that this market will continue to increase in the future. The direct use of reactors in medicine is actually made by the Boron Neutron capture Therapy (BNCT) for the treatment of glioblastoma, which kills about 15.000 people in Europe each year. For this promising technique, HFR is the most advanced for experimental possibilities and treatment studies. Medical research is also made in other promising fields: the use beam tubes for characterizing of prostheses and bio-medical materials, alpha-immuno therapy products, new types of radioisotopes, new types of illness to be treated by BNCT, etc. (author)

  20. Characterisation of crystal matrices and single pixels for nuclear medicine applications

    International Nuclear Information System (INIS)

    Herbert, D.J.; Belcari, N.; Camarda, M.; Del Guerra, A.; Vaiano, A.

    2005-01-01

    Commercially constructed crystal matrices are characterised for use with PSPMT detectors for PET system developments and other nuclear medicine applications. The matrices of different scintillation materials were specified with pixel dimensions of 1.5x1.5 mm 2 in cross-section and a length corresponding to one gamma ray interaction length at 511 keV. The materials used in this study were BGO, LSO, LYSO, YSO and CsI(Na). Each matrix was constructed using a white TiO loaded epoxy that forms a 0.2 mm septa between each pixel. The white epoxy is not the optimum choice in terms of the reflective properties, but represents a good compromise between cost and the need for optical isolation between pixels. We also tested a YAP matrix that consisted of pixels of the same size specification but was manufactured by a different company, who instead of white epoxy, used a thin aluminium reflective layer for optical isolation that resulted in a septal thickness of just 0.01 mm, resulting in a much higher packing fraction. The characteristics of the scintillation materials, such as the light output and energy resolution, were first studied in the form of individual crystal elements by using a single pixel HPD. A comparison of individual pixels with and without the epoxy or dielectric coatings was also performed. Then the matrices themselves were coupled to a PSPMT in order to study the imaging performance. In particular, the system pixel resolution and the peak to valley ratio were measured at 511 and 122 keV

  1. Nuclear medicine in bone diagnostics

    International Nuclear Information System (INIS)

    Feine, U.; Mueller-Schauenburg, W.

    1985-01-01

    This book on nuclear medicine in bone diagnostics and other complementary imaging methods is composed out of the 51 presentations of the 2nd Tuebinger bone symposium held on the 11th and 12th January 1985; it gives an overview of newer methods of nuclear medicine and other imaging methods such as magnetic-resonance tomography and sonography. While the 1st Tuebinger Symposium in January 1981 dealt with the clinical application of classical bone scintigraphy and the possibilities of the results of differential diagnosis, the present book is concerned with indications, alternative radiopharmaceuticals for skeleton scintigraphy and other techniques. The intention is to give a survey of the developments made over the last few years. (orig./MG) [de

  2. Nuclear medicine and densitometry

    International Nuclear Information System (INIS)

    Mazess, R.B.; Wahner, H.M.

    1988-01-01

    Several reports and books over the past decade have summarized bone measurement methods. This chapter serves as an update on those with particular reference to nuclear medicine approaches to bone density and skeletal uptake. Bone densitometry approaches include singe-photon absorptiometry(SPA) and dual-photon absortiometry neutron activation (DPA) of calcium, Compton scattering, ultrasound measurements and uptake of diphosphonates. Of these only SPA and DPA are used clinically; the other methods are largely experimental or investigational. Radiographic morphometry, radiographic indices, and X-ray QCT are dealt with

  3. Nuclear medicine radiation dosimetry

    CERN Document Server

    McParland, Brian J

    2010-01-01

    Complexities of the requirements for accurate radiation dosimetry evaluation in both diagnostic and therapeutic nuclear medicine (including PET) have grown over the past decade. This is due primarily to four factors: growing consideration of accurate patient-specific treatment planning for radionuclide therapy as a means of improving the therapeutic benefit, development of more realistic anthropomorphic phantoms and their use in estimating radiation transport and dosimetry in patients, design and use of advanced Monte Carlo algorithms in calculating the above-mentioned radiation transport and

  4. Therapeutic applications of Rhenium-188 in nuclear medicine and oncology - Current status and expected future perspectives

    International Nuclear Information System (INIS)

    Knapp, F. F. Jr.

    2005-01-01

    Full text: The increasing use of unsealed radioactive targeting agents for cancer treatment requires the routine availability of cost-effective radioisotopes. Rhenium-188 (Re-188; half-life 16.9 hours) is a high-energy beta-emitter (E max 2.12 MeV), readily available no- max carrier-added from the alumina-based tungsten-188 (half-life 69 days)/rhenium-188 generator system. Rhenium-188 also emits a 155 keV (15%) gamma photon, permitting gamma camera imaging for biodistribution and dosimetry evaluation. The versatile chemistry of rhenium allows attachment to a wide variety of targeting molecules for Re-188 applications in nuclear oncology for both palliative metastatic treatment and targeted tumor therapy - radionuclide synovectomy, and coronary restenosis therapy. The long parent half-life and consistent performance provide an indefinite generator shelf-life of several months with high Re-188 elution yields (75-85 %) and consistently low W-188 parent breakthrough ( -6 ). Simple post-elution concentration methods have been developed which provide very high specific volume solution of Re-188 for radiolabeling (> 700 mCi/mL saline/1 Ci generator). Over 60 physician-sponsored clinical trials are currently in progress worldwide with applications in nuclear medicine, nuclear oncology and interventional cardiology. A variety of Re-188-labeled therapeutic radiopharmaceuticals and devices are being developed for clinical trials currently in progress for treatment of both benign and metastatic oncological disorders. Palliation of metastatic bone pain with Re-188-HEDP - prepared from a simple 'kit' - has been demonstrated as a cost-effective alternative to similar agents. Recent studies have in fact demonstrated the enhancement of progression-free interval and survival time by repeated Re-188-HEDP injections to patients with metastatic disease from prostate cancer. The use of the Re-188-labeled antiNCA95 (CD66) antibody in conjunction with external beam irradiation is an

  5. Impact of the application of criteria of internal monitoring in radiological protection programmes in nuclear medicine services

    International Nuclear Information System (INIS)

    Dantas, B.M.; Dantas, A.L.A.; Juliao, L.Q.C.; Lourenco, M.C.; Melo, D.R.

    2005-01-01

    The manipulation of open sources in Nuclear Medicine services involves risks of external exposure and internal contamination. The radiological protection plan of facilities licensed by CNEN - Brazilian Nuclear Energy Commission - must include the evaluation of such risks and propose a programme of individual monitoring to control exposure and ensure the maintenance of conditions of radiation safety. The IAEA - International Atomic Energy Agency - recommendations presented in the Safety Guide RS-G-1.2 suggest that an internal worker monitoring program be implemented where there is a possibility of internal contamination lead to effective dose committed annual values equal to or greater than 1 mSv. This paper presents the application of such criteria to the radionuclides most frequently used in the field of Nuclear Medicine, taking into account the normal conditions of handling and the ranges of activity authorized by CNEN. It is concluded that iodine 131 manipulation for therapeutic purposes is the practice that presented the greatest risk of internal exposure of workers, requiring the adoption of a programme of internal monitoring of Nuclear Medicine services

  6. Nuclear medicine and prostheses

    International Nuclear Information System (INIS)

    Bordenave, L.; Baquey, Ch.

    2004-01-01

    Whatever the bio-material, prosthesis or medical device concerned, from design to experimental then clinical validation, nuclear medicine (NM) techniques offer a unique opportunity in all indications, (in vitro diagnosis, in vivo diagnosis and therapy) to investigate, assess and predict the behaviour of the device, qualitatively and quantitatively. All research fields involving prostheses and their constitutive biomaterials may take advantage of NM. In order to review published works, one can analyze provided data according to two strategies: an upright one related to medical and surgical specialties that integrate NM and a more horizontal one, that is to describe what kind of contribution is brought by such investigations. The latter approach was preferred in our review. We discuss and illustrate benefits of NM in the following indications: as an in vitro tool, as an in vivo tool for the diagnosis i) of device integration in recipient, ii) of functional outcome after use or implantation, iii) and predictive assessment of undesirable side effects, iv) of occurrence of complications associated to the device implantation, v) of a new therapy efficiency; finally as in vivo tool of therapy. Tissue engineering and regenerative medicine domains with stem cell potential as well as that of medical device associated with vigilance are new fields in basic research and clinical assessment that seem increasingly promising for the nuclear physician and to which NM could and would contribute from molecule to integrated system in order to improve knowledge and achievement of prostheses. (author)

  7. Nuclear medicine and AIDS

    International Nuclear Information System (INIS)

    O'Doherty, M.J.; Kent and Canterbury Hospital, Canterbury; Nunan, T.O.

    1993-01-01

    The human immunodeficiency virus (HIV) infection and its associated illnesses in a relatively young population of patients provides an expanding role for nuclear medicine. The disease enforces a review of each department's infection control procedures. It has also resulted in an increase in the number of patients presenting with diseases such as Pneumocystis carinii pneumonia, Kaposi's sarcoma etc. which prior to the HIV epidemic were extremely rare. Thus in high risk patients the interpretation of abnormalities in nuclear medicine scans needs to include the spectrum of opportunistic infections and unusual tumours. The presence of opportunistic infections in the severely immunocompromised patient has led to the development of techniques not normally used, i.e. lung 99 Tc m -diethylenetriamine pentaacetate (DTPA) transfer/clearance, donor leukocyte scanning to allow rapid diagnosis of an abnormality. Radionuclide techniques are also used to monitor the effect of therapy directed at the HIV itself or against opportunistic infections. This review covers aspects of infection control as well as the use of radionuclides to investigate specific problems related to HIV infection and therapy of the associated disease processes. (author)

  8. Nuclear methods in medicine

    International Nuclear Information System (INIS)

    Wolfe, D.M.

    1997-01-01

    Physicists have created remarkably sophisticated instruments for the performance of experiments. With variable phase lags many of these have become useful in technology. In the medical field NMD techniques have become commonplace under the rubric of Magnetic Resonance Imaging. Particle physics has developed sophisticated detectors for both charged and neutral particles. Many of these also have been adapted to medical uses. In both radiology and nuclear medicine, pixel detectors based on designs originating at large-scale colliders, are becoming highly useful in replacing film and NaI as the primary means of X-ray and (-ray detection. Coupled with high-speed work stations, these new techniques allow exciting new imagining modalities. Many of these are based on the handling of digital images originally developed for astronomy. Thus, once again, fundamental science is making large contributions to the development of technology. In this talk, various examples of developments in digital mammography and digital detectors for nuclear medicine will be given. The possibilities for telemedicine will be discussed. (author)

  9. PNRI Pioneering the Establishment and Operation of the Tc-99m Generator Production Facility for Nuclear Medicine Applications

    International Nuclear Information System (INIS)

    Bulos, Adelina DM.; Borras, Ma. Teresa L.; Ciocson, Gregory R.; Mascariñas, Rommel D.C.; Nuñez, Ivy Angelica A.; Dela Rosa, Alumanda M.

    2015-01-01

    In response to the increasing demand in the nuclear medicine sector in the Philippines, the Philippine Nuclear Research Institute (PNRI) initiated the establishment of a radioisotope production facility. To date, the most commonly used radioisotope in nuclear medicine, Technetium-99m or Tc-99m has been successfully produced in the new laboratory, the PNRI facility has already obtained a license to operate from the Philippine FDA. The new facility is envisioned to meet the country’s requirements for all the major medical radioisotope starting with the local production of Tc-99m and the most commonly used Tc-99m radiopharmaceuticals. At present, all radioisotope supplies in the country are sourced overseas at price that varies accordingly. With the establishment of the PNRI’s laboratories, we now have a GMP-grade Tc-99m generator facility capable of producing 50 Tc-99m generators per batch. Instead of Tc-99m being imported, it will be the parent Mo-99m that will be transferred to PNRI facility from Mo-99 processing facilities overseas, contained in specialized transport containers and via airfreight arrangements so it can be processed locally to make Tc-99m generators. But, to make radiopharmaceuticals, the other non-radioactive components are needed to be sourced from abroad. Thus, it has become imperative to also locally produce these non-radioactive components. All of these components, radioactive and non-radioactive, from the radiopharmaceutical finished products which are utilized in nuclear medicine caters for the diagnosis and detection of critical and non-critical human illnesses. The completion of this program is foreseen as another concrete validation on the capacity of the Philippine as a country that is at par with advanced nations on competency and expertise in the research and development of nuclear medicine application for better healthcare delivery and management. (author)

  10. White paper of nuclear medicine

    International Nuclear Information System (INIS)

    2012-10-01

    This document aims at proposing a synthetic presentation of nuclear medicine in France (definition, strengths and weaknesses, key figures about practices and the profession, stakes for years to come), a description of the corresponding education (speciality definition, abilities and responsibilities, diploma content, proposition by the European Society of Radiology and by the CNIPI, demography of the profession), and an overview of characteristics of nuclear medicine (radio-pharmacy, medical physics, paramedical personnel in nuclear medicine, hybrid imagery, therapy, relationships with industries of nuclear medicine, relationships with health authorities)

  11. Nuclear analytical techniques in medicine

    International Nuclear Information System (INIS)

    Cesareo, R.

    1988-01-01

    This book acquaints one with the fundamental principles and the instrumentation relevant to analytical technique based on atomic and nuclear physics, as well as present and future biomedical applications. Besides providing a theoretical description of the physical phenomena, a large part of the book is devoted to applications in the medical and biological field, particularly in hematology, forensic medicine and environmental science. This volume reviews methods such as the possibility of carrying out rapid multi-element analysis of trace elements on biomedical samples, in vitro and in vivo, by XRF-analysis; the ability of the PIXE-microprobe to analyze in detail and to map trace elements in fragments of biomedical samples or inside the cells; the potentiality of in vivo nuclear activation analysis for diagnostic purposes. Finally, techniques are described such as radiation scattering (elastic and inelastic scattering) and attenuation measurements which will undoubtedly see great development in the immediate future

  12. Nuclear analytical techniques in medicine

    Energy Technology Data Exchange (ETDEWEB)

    Cesareo, R.

    1988-01-01

    This book acquaints one with the fundamental principles and the instrumentation relevant to analytical technique based on atomic and nuclear physics, as well as present and future biomedical applications. Besides providing a theoretical description of the physical phenomena, a large part of the book is devoted to applications in the medical and biological field, particularly in hematology, forensic medicine and environmental science. This volume reviews methods such as the possibility of carrying out rapid multi-element analysis of trace elements on biomedical samples, in vitro and in vivo, by XRF-analysis; the ability of the PIXE-microprobe to analyze in detail and to map trace elements in fragments of biomedical samples or inside the cells; the potentiality of in vivo nuclear activation analysis for diagnostic purposes. Finally, techniques are described such as radiation scattering (elastic and inelastic scattering) and attenuation measurements which will undoubtedly see great development in the immediate future.

  13. Artificial intelligence. Application of the Statistical Neural Networks computer program in nuclear medicine

    International Nuclear Information System (INIS)

    Stefaniak, B.; Cholewinski, W.; Tarkowska, A.

    2005-01-01

    Artificial Neural Networks (ANN) may be a tool alternative and complementary to typical statistical analysis. However, in spite of many computer application of various ANN algorithms ready for use, artificial intelligence is relatively rarely applied to data processing. In this paper practical aspects of scientific application of ANN in medicine using the Statistical Neural Networks Computer program, were presented. Several steps of data analysis with the above ANN software package were discussed shortly, from material selection and its dividing into groups to the types of obtained results. The typical problems connected with assessing scintigrams by ANN were also described. (author)

  14. Nuclear medicine and radiopharmacy

    International Nuclear Information System (INIS)

    Leon A, M. C.

    2008-12-01

    In the areas of Nuclear Medicine and Radiopharmacy frequently happens that the personnel that is incorporated as a candidate to serve as personnel occupationally exposed have varied skills, not necessarily have an ingrained culture of safety and radiation protection, some are resistant to adoption a work discipline and have very limited notions of normalization, including the safety basic standards. In fact, referring to the safety basic standards, concepts such as practice justification, protection optimization and dose limitation, can be very abstract concepts for such personnel. In regard to training strategies, it was noted that training in the work is an effective tool although it is very demanding for the learner but mainly for the teaches. The experts number that can occur in this manner is limited because it is an individualized system; however those from the process usually acquire a good preparation, which certainly includes theoretical aspects. For greater efficiency it is necessary that hospitals account facilities, procedures and personnel that might have an exclusive dedication to education and training of human resources. This would create a safety culture, alleviating the burdens of the already existing expertise and improves the training conditions. The Mexican Society of Radiological Safety (SMSR) can help in these efforts through the publication of guides aimed at work training, coordination and articulation of the possible courses already on the market and own the courses organization, workshops and conferences with more frequency. It would also serves that the SMSR acts as speaker with political actors, advocating for the courses validation offered by higher learning institutions, coordinating and promoting postgraduates in Nuclear Medicine and Radiopharmacy. (Author)

  15. Applications of radioisotopes in medicine

    International Nuclear Information System (INIS)

    Sivaprasad, N.

    2012-01-01

    The application of radioisotopes in medicine is many folds. They can be classified into two main groups. (a) The radioisotope tagged labeled compounds suitable for safe administration in the body for diagnosis of various diseases of vital organs such as brain, kidney, thyroid etc and for treatment known as radiotherapy (b) The sealed source of radioisotopes for utilizing the radiation emitted from the radioisotope for treatment, particularly for radiation therapy of cancer. The former application of radioisotope in the field of medicine has led to the formation of special branch of medicine termed Nuclear Medicine - the branch of medicine deals with the use of radioisotope in the from of radiopharmaceuticals for investigation, diagnosis and treatment of diseases. Radioisotopes in the form of radiolabelled compound and bio-chemicals that are pharmaceutically and radiologically safe for administration in the body for diagnosis and treatment are called radiopharmaceuticals. The radiopharmaceuticals are the results of world-wide effort to bring nuclear energy in a tangible form for diagnosis and treatment. Radioisotopes as radiopharmaceuticals thus constitute one of the key requirements for nuclear medicine investigation and radiotherapy. In the case of sealed radioisotope source the radiation emitted by the radioactive source is utilized for the treatment and this mode of treatment is called radiation therapy where no radioactive substance is administrated into the body. This does not form the part of nuclear medicine

  16. Development of molecular nuclear medicine

    International Nuclear Information System (INIS)

    Tang Ganghua

    2002-01-01

    The basic theory of molecular nuclear medicine is briefly introduced. The hot areas of molecular nuclear medicine including metabolic imaging and blood flow imaging, radioimmunoimaging and radioimmunotherapy, radioreceptor imaging and receptor-radioligand therapy, and imaging gene expression and gene radiation therapy are emphatically described

  17. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... can be detected with other diagnostic tests. Nuclear medicine imaging procedures use small amounts of radioactive materials – called radiotracers – that ... outweighs any risk. To learn more about nuclear medicine, visit Radiology Info dot org. Thank you for your ... of Use | Links | Site Map Copyright © 2018 Radiological Society of ...

  18. Nuclear medicine in emergency

    International Nuclear Information System (INIS)

    Mansi, L.; Rambaldi, P.F.; Cuccurullo, V.; Varetto, T.

    2005-01-01

    The role of a procedure depends not only on its own capabilities but also on a cost/effective comparison with alternative technique giving similar information. Starting from the definition of emergency as a sudden unexpected occurrence demanding immediate action, the role of nuclear medicine (NM) is difficult to identify if it is not possible to respond 24h a day, 365 days a year, to clinical demands. To justify a 24 h NM service it is necessary to reaffirm the role in diagnosis of pulmonary embolism in the spiral CT era, to spread knowledge of the capabilities of nuclear cardiology in reliability diagnosis myocardial infraction (better defining admission and discharge to/from the emergency department), to increase the number of indications. Radionuclide technique could be used as first line, alternative, complementary procedures in a diagnostic tree taking into account not only the diagnosis but also the connections with prognosis and therapy in evaluating cerebral pathologies, acute inflammation/infection, transplants, bleeding, trauma, skeletal, hepatobiliary, renal and endocrine emergencies, acute scrotal pain

  19. Mongolia and nuclear medicine development

    International Nuclear Information System (INIS)

    Onkhuudai, P.; Gonchigsuren, D.

    2007-01-01

    Full text: Mongolia is a large, landlocked and sparsely populated country in the northern part of Central Asia, located between Russia on the north and China on east, south and west. Its total land area of 1.5 millions square kilometers is about the size if India or large than Alaska, but contains only 2.3 million population or 1.3 person per square kilometer. It is 2400 kilometers long from east to west maximum of 1260 kilometers from north to south.The priority problems in health.Democratic political reforms since 1990 saw a major transformation process, which is aimed at changing the centrally planned economy to one based on market orient principles. Mongolia is in a gradual epidemiological transition from preponderance of infectious diseases towards non-communicable and degenerative diseases. Mean features of this transition are sharp decrease in mortality from infectious and parasitic diseases and sharp increase in mortality from diseases of the circulatory system and neoplasms. Life expectancy at birth was 65.7 year in 1997. Cardiovascular diseases and cancer are among the leading causes of death in Mongolia.Nuclear Medicine in Mongolia-1975-1981 Beginning First Medical Application of radioisotopes in 1972. First Rectilinear scanner. Single and dual scintillation detectors system, Thyroid Uptake Test; 1982-1999 Settlement, IAEA TC Project since 1982, Thematic Program on Health Care (RAS) since 1997, First Gamma Camera since 1997, Radioimmunological Laboratory and first Radioiodine treatment since 1982, Mongolian Society of Nuclear Medicine since 1982, Member of World and Federation of Nuclear Medicine and Biology since 1994, Member of Asia and Oceania Radionuclide Therapy Council , 2000 Development, First SPECT and Quantitative Measurement in 2000 Second Gamma Camera, New Thyroid Uptake System-Atomlab 950 PC Spectrometer Radioimmunological Laboratory replacement, Myocardial Perfusion Scintigraphy, Liver Cancer Treatment with Re-188, Radiosynovectomy with Re

  20. Nuclear medicine in developing nations

    International Nuclear Information System (INIS)

    Nofal, M.M.

    1985-01-01

    Agency activities in nuclear medicine are directed towards effectively applying techniques to the diagnosis and management of patients attending nuclear medicine units in about 60 developing countries. A corollary purpose is to use these techniques in investigations related to control of parasitic diseases distinctive to some of these countries. Through such efforts, the aim is to improve health standards through better diagnosis, and to achieve a better understanding of disease processes as well as their prevention and management. Among general trends observed for the region: Clinical nuclear medicine; Radiopharmaceuticals; Monoclonal antibodies; Radioimmunoassay (RIA); Nuclear imaging

  1. Radiation protection in nuclear medicine

    International Nuclear Information System (INIS)

    Corstens, F.

    1989-01-01

    Aspects of radiation protection in nuclear medicine and the role of the Dutch Society for Nuclear Medicine in these are discussed. With an effective dose-equivalence of averaged 3 mSv per year per nuclear medical examination and about 200.000 examinations per year in the Netherlands, nuclear medicine contributes only to a small degree to the total averaged radiation dose by medical treating. Nevertheless from the beginning, besides to protection of environment and personnel, much attention has been spent by nuclear physicians to dose reduction with patients. Replacing of relatively long living radionuclides like 131 I by short living radionuclides like 99m Tc is an example. In her education and acknowledgement policy the Dutch Society for Nuclear Medicine spends much attention to aspects of radiation reduction. (author). 3 tabs

  2. Essentials of nuclear medicine imaging

    CERN Document Server

    Mettler, Fred A. Jr

    2012-01-01

    Essentials of Nuclear Medicine Imaging, by Drs. Fred A Mettler and Milton J Guiberteau, provides the practical and comprehensive guidance you need to master key nuclear imaging techniques. From physics, instrumentation, quality control, and legal requirements to hot topics such as sodium fluoride, radiopharmaceuticals, and recommended pediatric administered doses and guidelines, this sixth edition covers the fundamentals and recent developments in the practice of nuclear medicine.

  3. Nuclear Medicine in Surgical Oncology

    International Nuclear Information System (INIS)

    Ndirangu, D.T.

    2009-01-01

    Defines nuclear medicine as a branch that utilizes nuclear technology for diagnosis and treatment of diseases.The principles of nuclear medicine are; it uses the principle that a certain radiopharmaceutical (tracer) will at a certain point in time have a preferential uptake by a particular body or tissue. it is imaged by use the use of detectors mounted in gamma cameras or PET (Position emission tomography) devices

  4. Asian School of Nuclear Medicine

    International Nuclear Information System (INIS)

    Sundram, F.X.

    2007-01-01

    A number of organisations are involved in the field of nuclear medicine education. These include International Atomic Energy Agency (IAEA), World Federation of Nuclear Medicine and Biology (WFNMB), Asia-Oceania Federation of Nuclear Medicine and Biology (AOFNMB), Society of Nuclear Medicine (SNM in USA), European Association of Nuclear Medicine (EANM). Some Universities also have M.Sc courses in Nuclear Medicine. In the Asian Region, an Asian Regional Cooperative Council for Nuclear Medicine (ARCCNM) was formed in 2000, initiated by China, Japan and Korea, with the main aim of fostering the spread of Nuclear Medicine in Asia. The Asian School of Nuclear Medicine (ASNM) was formed in February 2003, with the ARCCNM as the parent body. The Aims of ASNM are: to foster Education in Nuclear Medicine among the Asian countries, particularly the less developed regions; to promote training of Nuclear Medicine Physicians in cooperation with government agencies, IAEA and universities and societies; to assist in national and regional training courses, award continuing medical education (CME) points and provide regional experts for advanced educational programmes; and to work towards awarding of diplomas or degrees in association with recognised universities by distance learning and practical attachments, with examinations. There are 10 to 12 teaching faculty members from each country comprising of physicists, radio pharmacists as well as nuclear medicine physicians. From this list of potential teaching experts, the Vice-Deans and Dean of ASNM would then decide on the 2 appropriate teaching faculty member for a given assignment or a course in a specific country. The educational scheme could be in conjunction with the ARCCNM or with the local participating countries and their nuclear medicine organisations, or it could be a one-off training course in a given country. This teaching faculty is purely voluntary with no major expenses paid by the ASNM; a token contribution could be

  5. Maladministrations in nuclear medicine

    International Nuclear Information System (INIS)

    Smart, R.C.

    2002-01-01

    Maladministration has been defined as the mistaken administration of a radiopharmaceutical to a patient. Examples include the administration of the wrong radiopharmaceutical or the wrong activity to the correct patient or the administration of the correct radiopharmaceutical to the wrong patient. Although maladministrations are rare, lessons can be learnt from the incidents that do occur. Medical maladministrations and other radiation incidents are discussed by members of the NSW Hospital and University Radiation Safety Officers Group (HURSOG) at their bi-monthly meetings. During the three years of 1997-1999 fourteen incidents of maladministrations in nuclear medicine were reported. Analysis of these reports indicated that eight (57 %) were due to the wrong radiopharmaceutical having been administered. This usually occurred because the technologist had selected the wrong lyophilised agent when the radiopharmaceutical was being prepared, or selected the wrong vial of the reconstituted agent. For example, in one instance a vial of MAG3 was reconstituted instead of a vial of HMPAO. These mistakes occurred even though the vials were clearly labelled and sometimes had different coloured labels. Of the remaining 6 cases, two involved the wrong activity being administered due to a mis-read dose calibrator, two involved the wrong procedure being performed following a breakdown in communication and the final two incidents resulted in the wrong patient being administered the radiopharmaceutical. In order to minimise the possibility of recurrence of these incidents the NSW Radiation Advisory Council asked the NSW Branch of the Australian and New Zealand Society of Nuclear Medicine and HURSOG to jointly convene a Working Party to prepare Guidelines for the administration of radiopharmaceuticals. The Guidelines specify: 1. the procedure for the validation of the requested investigation on the request form 2. who should reconstitute, dispense and administer radiopharmaceuticals

  6. Future of nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Ganatra, R D

    1993-12-31

    When it comes to setting up nuclear medicine in a developing country, there is a group of people, who feel that such high technology has no place in a developing country. RIA is likely to remain the method of choice for the research laboratory. The use of radioisotopic label has many advantages compared to the use of an enzyme marker. Generally, iodination is simpler than the preparation of an enzyme labelled substance, especially since there has been no agreement as to which enzyme is best for substances as small as steroids or a large as viruses. In addition, there may be some change in the configuration of the enzyme or the substance to be labelled during the conjugation procedure. Monoclonal antibodies can provide virtually unlimited amounts of homogenous antibodies against a specific antigenic site. The heterogeneous antibodies are more likely to provide more sensitive assays than the monoclonal antibodies, although assays employing the latter are likely to be more specific. The optimal choice of the antiserum may depend on whether sensitivity or specificity is required for the assays

  7. Future of nuclear medicine

    International Nuclear Information System (INIS)

    Ganatra, R.D.

    1992-01-01

    When it comes to setting up nuclear medicine in a developing country, there is a group of people, who feel that such high technology has no place in a developing country. RIA is likely to remain the method of choice for the research laboratory. The use of radioisotopic label has many advantages compared to the use of an enzyme marker. Generally, iodination is simpler than the preparation of an enzyme labelled substance, especially since there has been no agreement as to which enzyme is best for substances as small as steroids or a large as viruses. In addition, there may be some change in the configuration of the enzyme or the substance to be labelled during the conjugation procedure. Monoclonal antibodies can provide virtually unlimited amounts of homogenous antibodies against a specific antigenic site. The heterogeneous antibodies are more likely to provide more sensitive assays than the monoclonal antibodies, although assays employing the latter are likely to be more specific. The optimal choice of the antiserum may depend on whether sensitivity or specificity is required for the assays

  8. Nuclear medicine imaging system

    Science.gov (United States)

    Bennett, Gerald W.; Brill, A. Bertrand; Bizais, Yves J. C.; Rowe, R. Wanda; Zubal, I. George

    1986-01-01

    A nuclear medicine imaging system having two large field of view scintillation cameras mounted on a rotatable gantry and being movable diametrically toward or away from each other is disclosed. In addition, each camera may be rotated about an axis perpendicular to the diameter of the gantry. The movement of the cameras allows the system to be used for a variety of studies, including positron annihilation, and conventional single photon emission, as well as static orthogonal dual multi-pinhole tomography. In orthogonal dual multi-pinhole tomography, each camera is fitted with a seven pinhole collimator to provide seven views from slightly different perspectives. By using two cameras at an angle to each other, improved sensitivity and depth resolution is achieved. The computer system and interface acquires and stores a broad range of information in list mode, including patient physiological data, energy data over the full range detected by the cameras, and the camera position. The list mode acquisition permits the study of attenuation as a result of Compton scatter, as well as studies involving the isolation and correlation of energy with a range of physiological conditions.

  9. Nuclear medicine in oncology

    International Nuclear Information System (INIS)

    Bishop, J.F.

    1999-01-01

    Cancer is increasingly prevalent in our society. There is a life-time risk that 1 in 3 Australian men and 1 in 4 Australian women will get cancer before the age of 75 years. Overall, 27% of the deaths in NSW are currently related to cancer. The common cancers for men are prostate, lung, melanoma, colon, rectum and bladder. For women the common cancers are breast, colon, melanoma, lung and unknown primary. However, overall lung cancer remains the major cause of cancer deaths (20%) followed by colorectal (13%), unknown site (8%), breast and prostate. Breast and lung cancer are the major causes of death in women. Recent information on 5 year survivals reveal good 5 year survival rates for breast (78.6%), prostate (72.4%) and melanoma (92%), while some tumours such as lung cancer (10.7%) have poor survival. Colon cancer has intermediate survival (57.1%). Projections for cancer incidence suggests rates of cancer will increase for colorectal cancer, melanoma, lung cancer in females but decrease for breast, lung in males and prostate cancer. Major strategic directions in cancer research are understanding carcinogenesis, identification of high risk groups, screening and early detection, chemo-prevention, new cancer therapies, combined modality therapy and quality of life issues. Nuclear medicine will play an important part in many of these areas

  10. Radioisotopes for nuclear medicine: the future

    International Nuclear Information System (INIS)

    Carr, S.W.

    1998-01-01

    Full text: Nuclear medicine occupies an important niche in the spectrum of medical capability. Since its initial application on a routine basis over 30 years ago its importance has continued to grow. For example, it is expected that over 430,000 Australians will have a nuclear medicine procedure in 1998. Current procedures using nuclear medicine are mainly concerned with diagnosis of oncology, cardiology and neurology. The main radioisotope used in nuclear medicine is Tc 99m, which is produced by a 'so called' Mo-Tc 99m generator. Other isotopes which currently find routine use are Ga-67, Th-201 and I-131. The selective uptakes by particular organs or structures is facilitated by the use of 'cold kits' which after the chemistry of the radioisotope many of the recent advances have been concerned with increasing the selectivity for a particular organ structure. Several of these new agents show increased selectivity using antibody a peptide recognition units

  11. Nuclear medicine training and practice in Turkey.

    Science.gov (United States)

    Ozcan, Zehra; Bozkurt, M Fani; Erbas, Belkıs; Durak, Hatice

    2017-05-01

    Nuclear medicine applications in Turkey started in the early 1950s, grew as an independent medical discipline and finally were recognized by the Ministry of Health in 1973. Later on, the professional organization of nuclear medicine physicians and other related professionals including radiopharmacists and technologists under the Turkish Society of Nuclear Medicine were established in 1975. Recently after completing more than a half century in Turkey, nuclear medicine has proved to be a strong and evolving medical field with more than 600 physicians serving for the changing needs of clinical practice throughout these years. This article describes past and present facts in this field and attempts to provide insights into the future which hopefully will be brighter than before.

  12. Nuclear medicine training and practice in Turkey

    Energy Technology Data Exchange (ETDEWEB)

    Ozcan, Zehra [Ege University School of Medicine, Department of Nuclear Medicine, Izmir (Turkey); Bozkurt, M. Fani; Erbas, Belkis [Hacettepe University School of Medicine, Department of Nuclear Medicine, Ankara (Turkey); Durak, Hatice [Dokuz Eyluel University School of Medicine, Department of Nuclear Medicine, Izmir (Turkey)

    2017-05-15

    Nuclear medicine applications in Turkey started in the early 1950s, grew as an independent medical discipline and finally were recognized by the Ministry of Health in 1973. Later on, the professional organization of nuclear medicine physicians and other related professionals including radiopharmacists and technologists under the Turkish Society of Nuclear Medicine were established in 1975. Recently after completing more than a half century in Turkey, nuclear medicine has proved to be a strong and evolving medical field with more than 600 physicians serving for the changing needs of clinical practice throughout these years. This article describes past and present facts in this field and attempts to provide insights into the future which hopefully will be brighter than before. (orig.)

  13. Monte Carlo simulation in nuclear medicine

    International Nuclear Information System (INIS)

    Morel, Ch.

    2007-01-01

    The Monte Carlo method allows for simulating random processes by using series of pseudo-random numbers. It became an important tool in nuclear medicine to assist in the design of new medical imaging devices, optimise their use and analyse their data. Presently, the sophistication of the simulation tools allows the introduction of Monte Carlo predictions in data correction and image reconstruction processes. The availability to simulate time dependent processes opens up new horizons for Monte Carlo simulation in nuclear medicine. In a near future, these developments will allow to tackle simultaneously imaging and dosimetry issues and soon, case system Monte Carlo simulations may become part of the nuclear medicine diagnostic process. This paper describes some Monte Carlo method basics and the sampling methods that were developed for it. It gives a referenced list of different simulation software used in nuclear medicine and enumerates some of their present and prospective applications. (author)

  14. Nuclear medicine training and practice in Turkey

    International Nuclear Information System (INIS)

    Ozcan, Zehra; Bozkurt, M. Fani; Erbas, Belkis; Durak, Hatice

    2017-01-01

    Nuclear medicine applications in Turkey started in the early 1950s, grew as an independent medical discipline and finally were recognized by the Ministry of Health in 1973. Later on, the professional organization of nuclear medicine physicians and other related professionals including radiopharmacists and technologists under the Turkish Society of Nuclear Medicine were established in 1975. Recently after completing more than a half century in Turkey, nuclear medicine has proved to be a strong and evolving medical field with more than 600 physicians serving for the changing needs of clinical practice throughout these years. This article describes past and present facts in this field and attempts to provide insights into the future which hopefully will be brighter than before. (orig.)

  15. Special monitoring in nuclear medicine

    International Nuclear Information System (INIS)

    Beltran, C.C.; Puerta, J.A.; Morales, J.

    2006-01-01

    Colombia counts with around 56 centers of Nuclear Medicine, 70 Nuclear Doctors and more of 100 Technologists in this area. The radioisotopes more used are the 131 I and the 99m Tc. The radiological surveillance singular in the country is carried out for external dosimetry, being the surveillance by incorporation of radioactive materials very sporadic in our media. Given the necessity to implement monitoring programs in the incorporation of radionuclides of the occupationally exposed personnel, in the routine practice them routine of Nuclear Medicine, it was implemented a pilot program of Special Monitoring with two centers of importance in the city of Medellin. This program it was carried out with the purpose of educating, to stimulate and to establish a program of reference monitoring with base in the National Program of Monitoring in the radionuclides Incorporation that serves like base for its application at level of all the services of Nuclear Medicine in the country. This monitoring type was carried out with the purpose of obtaining information on the work routine in these centers, form of manipulation and dosage of the radionuclides, as well as the administration to the patient. The application of the program was carried out to define the frequency of Monitoring and analysis technique for the implementation of a program of routine monitoring, following the recommendations of the International Commission of Radiological Protection. For their application methods of activity evaluation were used in urine and in 7 workers thyroid, of those which only two deserve an analysis because they presented important activities. The measures were carried out during one month, every day by means in urine samples and to the most critic case is practiced two thyroid measures, one in the middle of the period and another when concluding the monitoring. To the other guy is practiced an activity count in thyroid when concluding the monitoring period. The obtained result of the

  16. Nuclear medicine, a proven partnership

    International Nuclear Information System (INIS)

    Henderson, L. A.

    2009-01-01

    Full text:Ultrasonography is the modality of choice for demonstrating many cystic structures within the body. However nuclear medicine is often able to demonstrate functional disturbance where ultrasound and conventional radiography are unsuccessful. A case is presented in which a 16 day old male child presented to nuclear medicine with a right upper quadrant cyst found in ultrasound with exact location equivocal. Determining the location and nature of the cyst was essential to the treatment team for patient management. A hepatobiliary study was performed and evidence of a choledochal cyst was found. In partnership with ultrasound, nuclear medicine was able to identify a possibly malignant structure and consequently patient management was determined.

  17. A nuclear chocolate box: the periodic table of nuclear medicine.

    Science.gov (United States)

    Blower, Philip J

    2015-03-21

    Radioisotopes of elements from all parts of the periodic table find both clinical and research applications in radionuclide molecular imaging and therapy (nuclear medicine). This article provides an overview of these applications in relation to both the radiological properties of the radionuclides and the chemical properties of the elements, indicating past successes, current applications and future opportunities and challenges for inorganic chemistry.

  18. How to facilitate the practical application of Quality Systems in Nuclear Medicine

    International Nuclear Information System (INIS)

    Touzet, R.E.

    2002-01-01

    Aim: Which are the reasons for non-implementation of a Quality System in most of the nuclear medicine services in Latin America, in spite of the recommendations made by international agencies and of the absolute convenience involved in guaranteeing the quality of the health-care services rendered to the population? One of the projects of the Argentine Regulatory Authority was providing an answer to this question and finding the solution to the existing situation in a progressive manner. Materials and Methods: Within a set of about 400 NM service providers and with the support of the Argentine Association of Nuclear Medicine and Biology, an investigation was made in order to learn which were the opinions of their officials and staff (interviews, surveys and discussion meetings were performed). On the basis of the results, a strategy was developed involving the design of a 'basic quality system' to be used as an intermediate stage between the 'natural quality systems' and the 'certifiable quality systems', while the general requirements of the ISO 9000-2000 Standard were applied as a structure. Once an agreement was reached on the working program, several documents were widely distributed (Explanatory Guide, Format of the Quality Manual, etc.). Also, courses and practical workshops were carried out and advice was provided by e-mail. Currently, several additional documents are being developed in order to facilitate implementation, training and quality systems evaluation. Results: Some of the reasons for the scarce certification appeared to be as follows: The cost of certification is high and specialized advisors are required. The long time required causes disappointment. There are no economic stimuli because competition is based on costs and not on quality. Medical professionals are not trained in quality management during their graduate studies. The formal certification system does not allow for intermediate stages and is highly dependent on the contracted advisor

  19. Therapeutic nuclear medicine

    International Nuclear Information System (INIS)

    Baum, Richard P.

    2014-01-01

    Discusses all aspects of radionuclide therapy, including basic principles, newly available treatments, regulatory requirements, and future trends. Provides the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Explains the role of the therapeutic nuclear physician in effectively coordinating a diverse multidisciplinary team. Written by leading experts. The recent revolution in molecular biology offers exciting new opportunities for targeted radionuclide therapy. The selective irradiation of tumor cells through molecular biological mechanisms is now permitting the radiopharmaceutical control of tumors that are unresectable and unresponsive to either chemotherapy or conventional radiotherapy. In this up-to-date, comprehensive book, world-renowned experts discuss the basic principles of radionuclide therapy, explore in detail the available treatments, explain the regulatory requirements, and examine likely future developments. The full range of clinical applications is considered, including thyroid cancer, hematological malignancies, brain tumors, liver cancer, bone and joint disease, and neuroendocrine tumors. The combination of theoretical background and practical information will provide the reader with all the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Careful attention is also paid to the important role of the therapeutic nuclear physician in delivering the effective coordination of a diverse multidisciplinary team that is essential to the safe provision of treatment.

  20. Therapeutic nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Baum, Richard P. (ed.) [ENETS Center of Excellence, Bad Berka (Germany). THERANOSTICS Center for Molecular Radiotherapy and Molecular Imaging

    2014-07-01

    Discusses all aspects of radionuclide therapy, including basic principles, newly available treatments, regulatory requirements, and future trends. Provides the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Explains the role of the therapeutic nuclear physician in effectively coordinating a diverse multidisciplinary team. Written by leading experts. The recent revolution in molecular biology offers exciting new opportunities for targeted radionuclide therapy. The selective irradiation of tumor cells through molecular biological mechanisms is now permitting the radiopharmaceutical control of tumors that are unresectable and unresponsive to either chemotherapy or conventional radiotherapy. In this up-to-date, comprehensive book, world-renowned experts discuss the basic principles of radionuclide therapy, explore in detail the available treatments, explain the regulatory requirements, and examine likely future developments. The full range of clinical applications is considered, including thyroid cancer, hematological malignancies, brain tumors, liver cancer, bone and joint disease, and neuroendocrine tumors. The combination of theoretical background and practical information will provide the reader with all the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Careful attention is also paid to the important role of the therapeutic nuclear physician in delivering the effective coordination of a diverse multidisciplinary team that is essential to the safe provision of treatment.

  1. Infection diagnosis in nuclear medicine

    International Nuclear Information System (INIS)

    Martin-Comin, J.

    1997-01-01

    Full text. The clinical applicability of agents like 67 Ga and 111 In-labelled leukocytes began the era of infection imaging diagnosis in Nuclear Medicine, more than two decades ago. In this period other agents have appeared in the field. 99 m Tc-HMPAQ-leukocytes and 99 m Tc-anti granulocyte monoclonal antibodies (able to label white blood cells) and 111 In and 99 mTc-polyclonal immuno globulins (in cold kit presentation). These agents had widespread the use of Nuclear Medicine procedures in clinical practice. Nevertheless, there is not, up to now, an specific agent to diagnose infection and is some cases a second or third agent (i.e.: 99 mTc-colloid) is used to obtain an accurate diagnosis. Actually, research is orientated to the development of agents with low antigenic power (peptides or fragments of monoclonal antibodies), or other non immunogenic agents involved in the inflammation process (selectin, antibiotic). Some experiences have also been done with PET agents. The clinical usefulness of commercially available agents and the future possibilities of the new ones will be presented

  2. Radiosanitary control in nuclear medicine

    International Nuclear Information System (INIS)

    Degrossi, O.J.

    1987-01-01

    Nuclear Medicine has recently modified radiosanitary control standards for the three sectors involved: patients, personnel and general population. Nuclear Medicine does not constitute an important source of radiation, including patients and population, compared with radiology. The basic problems of radiosanitary controls are: the absorbed dose and the patient. Low risk deferred stochastic effects may appear with correct use of these controls. On the other hand, risk of stochastic consequences and non stochastic complications appear with incorrect applications. The following aspects should be considered for correct uses: A-1- The critical organ, which is not always the one under study. 2-The rest of the organism, specially the more sensitive organs. B- The radiopharmaceutical used, considering the following periods: physical, biological and effective. C-Technical and human resources that include quality control for the equipment. Radiosanitary control aims at a common objetive: dose limitation to the patient, personnel and general population. For this, it is necessary to accomplish the training programme for proffesional and technical personnel about quality control and to stablish basic standards for the equipment. Current law and regulations assign to the National Atomic Energy Comission the responsibility for controlling the use of radioisotopes and radiations in order to safeguard the health and life of the population. (M.E.L.) [es

  3. Diagnostic interventions in nuclear medicine

    International Nuclear Information System (INIS)

    Thrall, J.H.; Swanson, D.P.

    1989-01-01

    Diagnostic interventions in nuclear medicine may be defined as the coadministration of a nonradioactive drug or application of a physical stimulus or physiologic maneuver to enhance the diagnostic utility of a nuclear medicine test. The rationale for each interventional maneuver follows from the physiology or metabolism of the particular organ or organ system under evaluation. Diagnostic inference is drawn from the pattern of change in the biodistribution of the tracer in response to the intervention-induced change in metabolism or function. In current practice, the most commonly performed interventional maneuvers are aimed at studies of the heart, genitourinary system, hepatobiliary system, and gastrointestinal tract. The single most commonly performed interventional study in the United States is the stress Thallium-201 myocardial perfusion scan aimed at the diagnosis of coronary artery disease. The stress portion of the study is accomplished with dynamic leg exercise on a treadmill and is aimed at increasing myocardial oxygen demands. Areas of myocardium distal to hemodynamically significant lesions in the coronary arteries become ischemic at peak stress due to the inability of the stenotic vessel to respond to the oxygen demand/blood flow needs of the myocardium. Ischemic areas are readily recognized as photopenic defects on scans obtained immediately after exercise, with normalization upon delayed imaging. Diuresis renography is aimed at the differential diagnosis of hydroureteronephrosis. By challenging the urinary tract collecting structures with an augmented urine flow, dilated, unobstructed systems can be differentiated from systems with significant mechanical obstruction. 137 references

  4. Complementary alternative medicine and nuclear medicine

    International Nuclear Information System (INIS)

    Werneke, Ursula; McCready, V.Ralph

    2004-01-01

    Complementary alternative medicines (CAMs), including food supplements, are taken widely by patients, especially those with cancer. Others take CAMs hoping to improve fitness or prevent disease. Physicians (and patients) may not be aware of the potential side-effects and interactions of CAMs with conventional treatment. Likewise, their known physiological effects could interfere with radiopharmaceutical kinetics, producing abnormal treatment responses and diagnostic results. Nuclear medicine physicians are encouraged to question patients on their intake of CAMs when taking their history prior to radionuclide therapy or diagnosis. The potential effect of CAMs should be considered when unexpected therapeutic or diagnostic results are found. (orig.)

  5. Immersion cooling of silicon photomultipliers (SiPM) for nuclear medicine imaging applications

    International Nuclear Information System (INIS)

    Raylman, R.R.; Stolin, A.V.

    2016-01-01

    Silicon photomultipliers (SiPM) are compact, high amplification light detection devices that have recently been incorporated into magnetic field-compatible positron emission tomography (PET) scanners. To take full advantage of these devices, it is preferable to cool them below room temperature. Most current methods are limited to the cooling of individual detector modules, increasing complexity and cost of scanners made-up of a large number of modules. In this work we investigated a new method of cooling, immersion of the detector modules in non-electrically conductive, cooled liquid. A small-scale prototype system was constructed to cool a relatively large area SiPM-based, scintillator detector module by immersing it in a circulating bath of mineral oil. Testing demonstrated that the system rapidly decreased and stabilized the temperature of the device. Operation of the detector illustrated the expected benefits of cooling, with no apparent degradation of performance attributable to immersion in fluid. - Highlights: • Immersion cooling is new, simple and inexpensive method to cool solid state based nuclear medicine scanner. • Method successfully tested on a scaled version of an SiPM-based PET detector module. • Can be scaled up to cool a complete PET scanner.

  6. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... Disorders Video: The Basketball Game: An MRI Story Radiology and You Sponsored by Image/Video Gallery Your Radiologist Explains Nuclear Medicine Transcript Welcome to Radiology Info dot org Hello! I’m Dr. Ramji ...

  7. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... other diagnostic tests. Nuclear medicine imaging procedures use small amounts of radioactive materials – called radiotracers – that are ... However, because the amount of radiotracer used is small, the level of radiation exposure is relatively low ...

  8. Considerations regarding nuclear medicine terminology

    International Nuclear Information System (INIS)

    Als, C.

    2008-01-01

    This article through some examples shows us all the interest of the use of terminology in nuclear medicine. Each would find in it its interest, from the patient to the doctors in different disciplines. (N.C.)

  9. The teaching of nuclear medicine

    International Nuclear Information System (INIS)

    Bok, B.; Ducassou, D.

    1984-01-01

    Having first recalled the need of a specialized teaching in the field of nuclear medicine, the authors describe the training programmes now available in this sector for doctors, chemists and hospital-attendants [fr

  10. Nuclear Medicine National Headquarter System

    Data.gov (United States)

    Department of Veterans Affairs — The Nuclear Medicine National HQ System database is a series of MS Excel spreadsheets and Access Database Tables by fiscal year. They consist of information from all...

  11. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... or before abnormalities can be detected with other diagnostic tests. Nuclear medicine imaging procedures use small amounts ... relatively low and the benefit of an accurate diagnosis far outweighs any risk. To learn more about ...

  12. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... An MRI Story Radiology and You Sponsored by Image/Video Gallery Your Radiologist Explains Nuclear Medicine Transcript ... by a special camera and computer to create images of the inside of your body. If you’ ...

  13. [Costing nuclear medicine diagnostic procedures].

    Science.gov (United States)

    Markou, Pavlos

    2005-01-01

    To the Editor: Referring to a recent special report about the cost analysis of twenty-nine nuclear medicine procedures, I would like to clarify some basic aspects for determining costs of nuclear medicine procedure with various costing methodologies. Activity Based Costing (ABC) method, is a new approach in imaging services costing that can provide the most accurate cost data, but is difficult to perform in nuclear medicine diagnostic procedures. That is because ABC requires determining and analyzing all direct and indirect costs of each procedure, according all its activities. Traditional costing methods, like those for estimating incomes and expenses per procedure or fixed and variable costs per procedure, which are widely used in break-even point analysis and the method of ratio-of-costs-to-charges per procedure may be easily performed in nuclear medicine departments, to evaluate the variability and differences between costs and reimbursement - charges.

  14. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... you have any allergies. You may have some concerns about nuclear medicine. However, because the amount of ... You Sponsored by About Us | Contact Us | FAQ | Privacy | Terms of Use | Links | Site Map Copyright © 2018 ...

  15. VIIIth international symposium on nuclear medicine

    International Nuclear Information System (INIS)

    1986-01-01

    The conference proceedings contain 92 abstracts of submitted papers dealing with various applications of radioisotopes in diagnosis and therapy. The papers were devoted to scintiscanning, radioimmunoassay, tomography, the applications of nuclear magnetic resonance and electron microscopy in different branches - oncology, cardiology, neurology, histology, gynecology, internal medicine, etc. (M.D.)

  16. Radiation dose assessment in nuclear medicine

    International Nuclear Information System (INIS)

    Stabin, M.G.

    2002-01-01

    In any application involving the use of ionizing radiation in humans, risks and benefits must be properly evaluated and balanced. Radionuclides are used in nuclear medicine in a variety of diagnostic and therapeutic procedures. Recently, interest has grown in therapeutic agents for a number of applications in nuclear medicine, particularly in the treatment of hematologic and non-hematologic malignancies. This has heightened interest in the need for radiation dose calculations and challenged the scientific community to develop more patient-specific and relevant dose models. Consideration of radiation dose in such studies is central to efforts to maximize dose to tumor while sparing normal tissues. In many applications, a significant absorbed dose may be received by some radiosensitive organs, particularly the active marrow. This talk will review the methods and models used in internal dosimetry in nuclear medicine, and discuss some current trends and challenges in this field

  17. Radiation protection in nuclear medicine

    International Nuclear Information System (INIS)

    Chougule, Arun

    2014-01-01

    The branch of medical science that utilizes the nuclear properties of the radioactivity and stable nuclides to make diagnostic evaluation of anatomical and/or physiological conditions of the body and provide therapy with unsealed radioactive sources is called Nuclear Medicine (NM). The use of unsealed radionuclides in medicine is increasing throughout the world for diagnosis and treatment. As per UNSCEAR report more than 6 million nuclear medicine procedures are conducted in a year. However we know that radiation is double edged sword and if not used carefully will be harmful to patient as well as staff and therefore a nuclear medicine procedure should be undertaken only after proper justification and optimization. Nuclear medicine procedures are different than the X-ray diagnostic procedures as in NM, radioisotope is administered to patient and patient becomes radioactive. The NM staff is involved in unpacking radioactive material, activity measurements, storage of sources, internal transports of sources, preparation of radiopharmaceuticals, administration of radiopharmaceutical, examination of the patient, care of the radioactive patient, handling of radioactive waste and therefore receives radiation dose. This talk will discuss the various steps for radiation safety of patient, staff and public during Nuclear Medicine procedures so as to implementing the ALARA concept. (author)

  18. Nuclear Medicine Imaging

    Science.gov (United States)

    ... necesita saber acerca de... Estudios de Imagen de Medicina Nuclear Un procedimiento de medicina nuclear se describe algunas veces como unos rayos- ... través del cuerpo del paciente. Los procedimientos de medicina nuclear utilizan pequeñas cantidades de mate- riales radiactivos, ...

  19. Therapy in nuclear medicine

    International Nuclear Information System (INIS)

    Eftekhari, M.; Sadeghi, R.; Takavar, A.; Fard, A.; Saghari, M.

    2002-01-01

    Although there have been very significant development in the field of radionuclide therapy within the past 10 years, radionuclide therapy in the form of 131 I, 33 P,.... have been in use for over 46 years. Palliation of bone pain is a good example for radionuclide therapy. It has an especial role in advanced metastatic cancer. 32 P, 89 Sr-Cl, 186 Re-HEDP, 133 Sm-EDTMP, and 117 mSn-DTPA are used in these patients. They are usually effective and help to maintain a painless life for patients with advanced cancer. Although this kind of therapy is not as rapid as radiotherapy, its effect lasts longer. In addition re-treatment with these agents is safe and effective. Radioimmunotherapy is a new exciting technique in the radionuclide therapy. In this technique monoclonal antibodies or their fragments are labeled with a suitable radionuclide, these antibodies can irradiate tumor cells over a distance of some fraction of a millimeter. Bulky tumors are obviously unsuitable targets for Rit. Several antibodies specific for Cd 20 (B1 and 1 F 5) and CD 37 (Mb-1) labeled with 131 I have been used for hematologic malignancies with good response. Several antigens associated with carcinomas of various histologic types have been targeted for therapeutic purposes by antibodies labeled with different radionuclides. Other routes of administration like intraperitoneal, intrathecal, and intravesical have been used with different rates of success. Pre targeting techniques can be used to reduce unwanted radioactive concentration in normal tissues. The avidin-biotin system is an example, which exploits the high-affinity binding between avidin and biotin, and was first used with anti-Cea antibody. Radiation synovectomy is another aspect of radionuclide therapy 198 Au colloid, 90 Y resin colloid, and 165 Dy-FHMA are some of the radionuclides used in the field of hematology. There has been significant advances in the field of therapy in nuclear medicine in recent years, which are briefly

  20. XXIVth days of nuclear medicine

    International Nuclear Information System (INIS)

    1986-01-01

    Abstracts are presented of papers submitted to the 24th Days of Nuclear Medicine held in Opava, Czechoslovakia between Oct 9 and 11, 1985. The conference proceeded in three sessions, namely nuclear pediatrics, miscellaneous and technicians' session. The publication also contains abstracts of posters. (L.O.)

  1. Application of radioactive substances in research in nuclear medicine: current trends and radiation exposure to the study subjects

    International Nuclear Information System (INIS)

    Minkov, V.; Schwarz, E.R.; Bauer, B.; Nosske, D.; Erzberger, A.; Brix, G.

    2001-01-01

    Aim: Analysis of the application of radioactive substances in research in the field of nuclear medicine in human beings and of the resulting radiation exposure to study subjects. Methods: Assessment of applications for approval submitted in accordance with Paragraph 41 of the Radiation Protection Ordinance, evaluated by the Federal office for Radiation Protection together with the Federal Institute for Pharmaceuticals and Medical Products, within the period from 1997 to 1999. Results: The focus of the studies on the diagnostic application of radioactive substances in medicine evaluated has, since 1998, shifted from oncological to neurological and psychological aspects, while, at the same time, the number of PET studies increased constantly The proportion of healthy study subjects included in the diagnostic studies increased from 7 to 22%. The number of therapeutic applications of radioactive substances has, since 1997, undergone a three-fold increase, and in the process of this, the focus of attention lay within the area of radioimmuno-therapy and endovascular brachytherapy. The effective dose was, among up to 49% of the investigated healthy study subjects higher than 5 mSv, and among up to 6% of these subjects was at levels of over 20 mSv. Up to 22% of the patients received, within the scope of diagnostic studies, an effective dose of between 20 and 50 mSv. An exceeding of the 50 mSv limit occurred among up to 3% of the patients. Conclusions: In spite of the increasing numbers of PET applications, conventional nuclear medicine has maintained its importance in the field of medical research. Further developments in the areas of radiochemistry and molecular biology led to an increase in the importance of radio-immuno therapy. The evaluation of new radiopharmaceuticals and the extension of basic biomedical research, resulted in an increase in the proportion of healthy study subjects included in the studies. The radiation exposure among subjects resulting directly from

  2. Regulatory problems in nuclear medicine

    International Nuclear Information System (INIS)

    Vandergrift, J.F.

    1987-01-01

    Governmental involvement in the practice of medicine has increased sharply within the past few years. The impact on health care has, for the most part, been in terms of financial interactions between health care facilities and federally funded health services programs. One might say that this type of governmental involvement has indirect impact on the medical and/or technical decisions in the practice of nuclear medicine. In other areas, however, governmental policies and regulations have had a more direct and fundamental impact on nuclear medicine than on any other medical specialty. Without an understanding and acceptance of this situation, the practice of nuclear medicine can be very frustrating. This chapter is thus written in the hope that potential frustration can be reduced or eliminated

  3. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... medicine imaging to evaluate organ systems, including the: kidneys and bladder. bones. liver and gallbladder. gastrointestinal tract. ... help diagnose and evaluate: urinary blockage in the kidney. backflow of urine from the bladder into the ...

  4. Basics of radiobiology and nuclear medicine

    International Nuclear Information System (INIS)

    Kostadinova, I.; Hadjidekova, V.; Georgieva, R.

    2002-01-01

    The authors successively reveal the topics of the biological impact of radiation (radiobiology) and the diagnostic and the therapeutic application of radiopharmaceuticals (nuclear medicine). Data on the influence of radiation on subcellular, cellular, tissue and organ level are given, on early and late radiation changes, as well. Indication for the application of the different radionuclide methods in the diagnosis of the diseases in the endocrinology, nephrology, cardiology, gastroenterology, haematology of lungs, bones, tumors are pointed out and the main trends of the growing therapeutical use of nuclear medicine are presented. The aim is to teach students the nuclear medicine methods in the complex investigation of the patients, his preliminary preparation and the biological impact of radiation and its risk. Self assessment test for students are proposed and a literature for further reading

  5. Neuroimaging, nuclear medicine

    International Nuclear Information System (INIS)

    Kato, Takashi; Ito, Kengo; Arahata, Yutaka

    2007-01-01

    This chapter describes radionuclide imaging as it related to neurodegenerative dementias like Alzheimer's disease (AD), idiopathic Parkinson's disease (PD), and normal aging, among the various diseases of the elderly. The role of neuroimaging with nuclear medicine is to detect changes in neural activities that are caused by these diseases. Such changes may be indirect phenomena, but the imaging of neural functions provides physicians with useful, objective information regarding pathophysiology in the brain. Brain activities change with age, with the elderly showing decreased brain function in memory, execution, and attention. Age-dependent reduction in the global mean of cerebral blood flow (CBF) has been reported in many studies that have used X-133 and O-15 labeled gas, the spatial resolution of which is low. Partial volume correction (PVC) is available through the segmentation of grey matter from high-resolution T1-weighted magnetic resonance imaging. Meltzer reported that age-related change disappeared after PVC. The relative distribution of CBF and glucose metabolism has been examined on a voxel-by-voxel basis in many studies. The areas negatively correlated with age are the anterior part of the brain, especially the dorsolateral and medial frontal areas, anterior cingulate cortices, frontolateral and perisylvian cortices, and basal ganglia. The areas positively correlated with age are the occipital lobe, temporal lobe, sensorimotor cortex, and primary visual cortex. It is not easy to define ''normal aging''. Aged people tend to have the potential for diseases like cerebral ischemia caused by arteriosclerosis. Ischemia results in volume loss of the gray matter and CBF. The ApoE e4 gene is a risk factor for AD, and carriers of the ApoE e4 allel show CBF-like AD even at a relatively young age. Hypo-glucose metabolism in the posterior cingulate cortex is seen in 5% of normal people over 50 years of age. This Alzheimer-like CBF/metabolic pattern needs further

  6. The keys for success in the application of quality systems in nuclear medicine and radiotherapy

    International Nuclear Information System (INIS)

    Touzet, R.; Larcher, A.M.; Menossi, C.A.; Sanchez, G.D.

    2000-01-01

    Observations indicate that the extensive use of pre-established recipes for the implementation of quality assurance systems in hospital practice has not led to satisfactory results. One of the reasons for their failure is the presence of several manuals that were named 'Quality Assurance' but that, actually, they are just simple checking lists for quality control of equipment units. Success in total quality management must be based on a system developed by the personnel in the installation, which must not be based on pre-existing standards or manual., but on unprejudiced analyses of all the possible reasons for failure. The analyses are carried out using the classical tools for detecting sources of error (fishtail diagram, Pareto, statistical control, etc.). It is essential that all members of the service staff, with no exceptions, participate effectively in the research, planning and implementation of the quality assurance program, then motivation and involvement will be assured. The Quality Assurance Program must, definitely and simultaneously, include three objectives related to quality, safety and productivity: 1. Ensure the quality of the results obtained, avoiding errors in the activities performed. 2. Minimize unnecessary or erroneous irradiation in both patients and operators (optimization). 3. Obtain growing economic benefits. One of the conflictive areas is clinical accuracy. It depends on the physician's interpretation and diagnosis, while - in many cases - it is related to criteria that are hardly quantifiable and based on experience and on the medical rules of the art that are often approached by means of periodical peer reviews. The quality of the software used in computerized therapeutic planning must also be preserved with special care. Another conflicting area is that of the interfaces between the hospital management and the person responsible for the Nuclear Medicine or Radiotherapy Service, especially when 'resident' services are granted by third

  7. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... used in children with cancer, epilepsy and back pain. top of page What does the equipment look ... being recorded. Though nuclear imaging itself causes no pain, children may experience some discomfort from having to ...

  8. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... may be placed into the bladder, which may cause temporary discomfort. It is important that your child ... images are being recorded. Though nuclear imaging itself causes no pain, children may experience some discomfort from ...

  9. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... resonance imaging (MRI) to produce special views, a practice known as image fusion or co-registration. These ... your doctor of any recent illnesses or other medical conditions. Depending on the type of nuclear scan ...

  10. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... help diagnose childhood disorders that are present at birth or that develop during childhood. It provides unique ... diagnose childhood disorders that are congenital (present at birth) or that develop during childhood. Physicians use nuclear ...

  11. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... exams at the same time. An emerging imaging technology, but not readily available at this time is ... your doctor of any recent illnesses or other medical conditions. Depending on the type of nuclear scan ...

  12. Proceedings of the forty third annual conference of Society of Nuclear Medicine India: empowering modern medicine with molecular nuclear medicine

    International Nuclear Information System (INIS)

    2011-01-01

    Theme of the 43rd Annual Conference of the Society of Nuclear Medicine India is 'empowering modem medicine with molecular nuclear medicine'. Keeping the theme in mind, the scientific committee has arranged an attractive and comprehensive program for both physicians and scientists reflecting the multimodality background of Nuclear Medicine and Metabolic Imaging. During this meeting the present status and future prospects of Nuclear medicine are discussed at length by esteemed faculty in dedicated symposia and interesting featured sessions which are immensely facilitate in educating the participants. Nuclear Medicine has come a long way since the first applications of radioiodine in the diagnosis of thyroid disease. The specialty of nuclear medicine in India is growing very rapidly. Technology continues to push the field in new directions and open new pathways for providing optimal care to patients. It is indeed an exciting time in the world of imaging and in the field of nuclear medicine. Innovative techniques in hardware and software offer advantages for enhanced accuracy. New imaging agents, equipment, and software will provide us with new opportunities to improve current practices and to introduce new technology into the clinical protocols. Papers relevant to INIS are indexed separately

  13. Quality assurance in nuclear medicine

    International Nuclear Information System (INIS)

    Paras, P.

    1978-01-01

    Quality assurance practices must be followed throughout the entire nuclear medicine process, from the initial decision to perform a particular procedure, through the interpretation and reporting of the results. The various parameters that can be defined and measured in each area must be monitored by quality control tests to assure the excellence of the total nuclear medicine process. The presentation will discuss each of the major areas of nuclear medicine quality control and their interaction as a part of the entire system. Quality control testing results and recommendations for measurements of radioactivity distribution will be described with emphasis on imaging equipment and dose calibrating instrumentation. The role of the health physicist in a quality assurance program will be stressed. (author)

  14. Nuclear Medicine on the net

    International Nuclear Information System (INIS)

    Graney, K.; Lin, P.C.; Chu, J.; Sathiakumur, C.

    2003-01-01

    Full text: To gain insight into Internet usage as a potential means of communicating with clinicians. Method: 200 clinicians within the South Western Sydney Health Area were surveyed by mail. Questionnaire details included Internet access, frequency of access, interest in department web site, suitability of content and interest in electronic bookings. The total response rate was 37% (74/200). General Practitioners comprised 46% of the respondents, and specialists 54%. All respondents had access to the Internet (44% from home only, 8% from work, 48% from both locations), with 57% accessing the Web daily. There was a high overall interest by respondents in accessing a Nuclear medicine web site, particularly for information and results, but a relative reluctance to consider electronic bookings. The following table outlines the respondents in detail. Our results indicate that a Nuclear Medicine web site has the potential to be an effective means of communicating with clinicians. Copyright (2003) The Australian and New Zealand Society of Nuclear Medicine Inc

  15. Radiation protection in nuclear medicine

    International Nuclear Information System (INIS)

    Seeburrun, V.

    2013-04-01

    Radiation protection in nuclear medicine in this project is concerned with the reduction of doses to workers, patients and members of the public. Protection of workers is achieved by adopting good personal habits, good housekeeping, proper use of personal protective devices and equipment, attend training and have continuous education. Exposure to radiation of workers and the members of the public are minimised by proper management of radioactive waste and safe transport of radioactive material. The design and shielding of a nuclear medicine department shall further provide for the protection of the worker, the patient and the general public. Protection of patient is achieved by justifying the procedure, delivering the minimum radiation dose possible to the patient while obtaining the best image quality and applying guidance levels. Special considerations shall be given to pregnant and breast-feeding patients. Quality assurance programme through image quality, radiopharmaceutical quality and patient records on nuclear medicine procedures shall provide assurance to the patient. (au)

  16. Application of accelerators in industry, medicine and for environmental research in Almaty Institute of Nuclear Physics

    International Nuclear Information System (INIS)

    Lyssukhin, S.N.; Arzumanov, A.A.

    2001-01-01

    Full text: The Institute of Nuclear Physics in Almaty is the only Kazakhstan institution with a significant activity at the national level in the field of physics of accelerators, their application and associated technology. Three accelerators of different type are being used in the Institute: high power electron beam accelerator, isochronous cyclotron and heavy ion electrostatic tandem. Electron beam accelerator ELV-4 - This high power machine is only electron beam irradiation facility of industrial scale in the Republic. It was produced by Budker Institute of Nuclear Physics, Novosibirsk, Russia and installed in Almaty in 1991 for development of radiation technology in Kazakhstan. The accelerator generates electron beams of following parameters: Energy range (MeV) 1.0-1.5; Max. beam power (kW) 40; Max. beam current (mA) 40. The machine is equipped with beam scanning system, extraction device with output window 980x75 mm 2 and chain conveyer for irradiated material supply. Tn the time being the accelerator is regularly used for radiation cross-linking technology and for sterilization. Cross-linking technology is the base of high quality roof material production for building industry. Raw ethylene-propylene rubber mixture is rolled as strip of 50 m length, 1 m width, 1 mm thickness and then irradiated by dose of about 120 kGy. The final product is waterproof flexible material, very stable in hard atmospheric conditions and non sensitive to sun UV radiation. Sterilization of medical materials and items is not traditional application of such low energy installations but due to uniqueness of this accelerator in Kazakhstan and high actuality of the task for the Republic this technology was developed in INP. Hermetically packed items (medical cotton , bandages, syringes, surgical gloves, small plastic bottles) with thickness less than penetration range of 1.5 MeV electrons are put at the conveyer as mono-layer and irradiated by sterilizing dose of 25 kGy. Isochronous

  17. Development of dynamic kidney phantom system and its evaluation of usability of application in nuclear medicine

    International Nuclear Information System (INIS)

    Park, Hoon Hee; Lyu, Kwang Yeul; Lee, Ju Young; Kim, Sang Wook; Jin, Gye Hwan

    2013-01-01

    Currently, commercially available phantom can reproduce and evaluate only a static situation, the study is incomplete research on phantom and system which is can confirmed functional situation in the kidney by time through dynamic phantom and blood flow velocity, various difference according to the amount of radioactive. Therefore, through this study, it has produced the dynamic kidney phantom to reproduce images through the dynamic flow of the kidney, it desires to evaluate the usefulness of nuclear medicine imaging. The production of the kidney phantom was fabricated based on the normal adult kidney, in order to reproduce the dynamic situation based on the fabricated kidney phantom, in this study, it was applied the volume pump that can adjust the speed of blood flow, so it can be integrated continuously radioactive isotopes in the kidney by using 99m Tc-pertechnate. Used the radioactive isotope was supplied through the two pump. It was confirmed the changes according to the infusion rate, radioactive isotopes and the different injection speeds on the left and right, analysis of the acquired images was done by drawn five times ROI in order to check the reproducibility of each on the front and rear of the kidney and bladder. Depending on the speed of injection, radioisotope was a lot of integrated and emissions up when adjusting the pressure of the pump as 30 stroke, it was the least integrated and emissions up when adjusting as 40 stroke. The integration of the left and right kidney was not reached in the amount of the highest when adjusting as 10 stroke. In the changes according to the amount of the radioactive isotope, 0.6 mCi (22.2 MBq), 0.8 mCi (29.6 MBq) was showed up similar tendency but, in the result of the different injection 0.8 mCi, it was showed up counts close to double of 0.6 mCi. In the result of the differently injection speed of the left and right kidney, as a result of different conditions that injection speed was 20 stroke through left kidney

  18. Historic images in nuclear medicine

    DEFF Research Database (Denmark)

    Hess, Søren; Høilund-Carlsen, Poul Flemming; Alavi, Abass

    2014-01-01

    In 1976, 2 major molecular imaging events coincidentally took place: Clinical Nuclear Medicine was first published in June, and in August researchers at the Hospital of the University of Pennsylvania created the first images in humans with F-FDG. FDG was initially developed as part of an evolution...... set in motion by fundamental research studies with positron-emitting tracers in the 1950s by Michel Ter-Pegossian and coworkers at the Washington University. Today, Clinical Nuclear Medicine is a valued scientific contributor to the molecular imaging community, and FDG PET is considered the backbone...

  19. Patient preparation for nuclear medicine studies

    International Nuclear Information System (INIS)

    Stathis, V.J.; Cantrell, D.W.; Cantrell, T.J.

    1987-01-01

    In this chapter are described methods of patient preparation that can favorably affect the outcome of nuclear medicine studies in specific situations. Some of these practices may be considered essential to the success of the nuclear medicine procedure, whereas others may be thought of simply as a means of obtaining more valid or reliable information. Regardless of relative importance, each of the preparatory methods discussed can contribute to the quality of the respective study and can serve as a means of maximizing the value of nuclear medicine procedures. The specific patient preparation techniques discussed in this chapter may not be readily applicable to every practice setting or situation. These or similar procedures can be used or modified as necessary. It is important, however, that when new protocols are developed, the rationale and theoretical basis of each technique be considered

  20. Mentoring and the Nuclear Medicine Technologist.

    Science.gov (United States)

    Burrell, Lance

    2018-06-08

    The goal of this article is to give an overview of mentoring for nuclear medicine technologists (NMT). Mentoring is an integral part of the training and practice in the field of nuclear medicine technology. There is a great need for NMTs to continue involvement in mentorship so that we can develop and maintain the talent and leadership that the field needs. In this article, definitions of mentorship will be provided. Then, how mentoring can work; including different methods and techniques will be covered. Next, the benefits of mentoring will be discussed. Finally, advice for improved application will be presented. Throughout, this article will discuss how mentoring applies to the NMT. Copyright © 2018 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

  1. Nuclear medicine in the Philippines

    International Nuclear Information System (INIS)

    Villadolid, Leland.

    1978-01-01

    This article traces the history of nuclear medicine in the country from the time the first radioisotope laboratory was set up by the Philippine General Hospital about 1955, to the not too satisfactory present facilities acquired by hospitals for diagnosis, treatment and investigation of diseases. It is in research, the investigation of disease that is nuclear medicine's most important area. The Philippine Atomic Energy Commission (PAEC) has pioneered in the conducting of courses in the medical uses of radioisotopes. The local training of nuclear manpower has been continued and updated and foreign fellowships are availed of through the cooperation of IAEA. Quite a number are already trained also in the allied fields that support the practice of nuclear medicine. However the brain drain has seriously affected the number of trained staff of medical units. Discussed and presented is the growth of the medical use of radioisotopes which are locally produced by PAEC. In order to benefit from the full advantage that nuclear medicine can do to a majority of Filipinos, the government should extend its financial support in acquiring such facilities to equip strategic hospitals in the country and support training programs. The Philippine has the expertise to start the expansion but only with adequate provision of funds will our capacity turn into reality. (RTD)

  2. Quality management audits in nuclear medicine practices

    International Nuclear Information System (INIS)

    2008-12-01

    An effective management system that integrates quality management (QM) is essential in modern nuclear medicine departments in Member States. The IAEA, in its Safety Standards Series, has published a Safety Requirement (GS-R-3) and a Safety Guide (GS-G-3.1) on management systems for all facilities. These publications address the application of an integrated management system approach that is applicable to nuclear medicine organizations as well. Quality management systems are maintained with the intent to continuously improve effectiveness and efficiency, enabling nuclear medicine to achieve the expectations of its quality policy, and to satisfy its customers. The IAEA has a long history of providing assistance in the field of nuclear medicine to its Member States. Regular quality audits and assessments are essential for modern nuclear medicine departments. More importantly, the entire QM and audit process has to be systematic, patient oriented and outcome based. The management of services should also take into account the diversity of nuclear medicine services around the world and multidisciplinary contributions. The latter include clinical, technical, radiopharmaceutical and medical physics procedures. Aspects of radiation safety and patient protection should also be integral to the process. Such an approach ensures consistency in providing safe, quality and superior services to patients. Increasingly standardized clinical protocol and evidence based medicine is used in nuclear medicine services, and some of these are recommended in numerous IAEA publications, for example, the Nuclear Medicine Resources Manual. Reference should also be made to other IAEA publications such as the IAEA Safety Standards Series, which include the regulations for the safe transport of nuclear material and on waste management as all of these have an impact on the provision of nuclear medicine services. The main objective of this publication is to introduce a routine of conducting an

  3. The 3rd Sino-Japan nuclear medicine conference

    International Nuclear Information System (INIS)

    1999-01-01

    The 3rd Sino-Japan Nuclear Medicine Conference was hold on May 11-13, 1999 in Xi'an of China by Chinese Society of Nuclear Medicine, Japanese Society of Nuclear Medicine, Chinese Medicine Association and Japan-China Medicine Association. 62 articles were published in the proceeding of the conference. The contents of the articles include development and application of the radioisotopes (such as Tc-99, I-125, I-131, F-18, In-111, Tl-201, Ga-67, Sm-153, Re-188) and its radiopharmaceuticals, but application also include radiotherapy and diagnosis in the oncology and pathology by SPECT and PET

  4. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... may be placed into the bladder, which may cause temporary discomfort. It is important that your child remain very still while the images are being recorded. Though nuclear imaging itself causes no pain, children may experience some discomfort from ...

  5. Nuclear medicine consensus

    International Nuclear Information System (INIS)

    Camargo, Edwaldo E.; Marin Neto, Jose Antonio; Naccarato, Alberto F.P.; Ramires, Jose Antonio F.; Castro, Iran de; Paiva, Eleuses Vieira; Thom, Anneliese F.; Barroso, Adelanir; Blum, Bernardo; Hollanda, Ricardo; Mansur, Antonio de Padua

    1995-01-01

    The use of nuclear methods in cardiovascular diseases is studied concerning diagnosis, risk, prognosis, indications and accuracy. Aspects concerning chronic coronary artery disease, myocardial ischemia, myocardial infarction, viable myocardium, valvular heart disease, ventricular dysfunction, heart transplant, congenital heart diseases in adults, are discussed

  6. Introductory physics of nuclear medicine. Third edition

    International Nuclear Information System (INIS)

    Chandra, R.

    1987-01-01

    The new third edition includes essential details and many examples and problems taken from the routine practice of nuclear medicine. Basic principles and underlying concepts are explained, although it is assumed that the reader has some current use as a bone densitometer. For resident physicians in nuclear medicine, residents in pathology, radiology, and internal medicine, and students of nuclear medicine technology, the third edition offers a simplified and reliable approach to the physics and basic sciences of nuclear medicine

  7. Computers. A perspective on their usefulness in nuclear medicine

    International Nuclear Information System (INIS)

    Loken, M.K.; Williams, L.E.; Ponto, R.A.; Ganatra, R.D.; Raikar, U.; Samuel, A.M.

    1977-01-01

    To date, many symposia have been held on computer applications in nuclear medicine. Despite all of these efforts, an appraisal of the true utility of computers in the day-to-day practice of nuclear medicine is yet to be achieved. Now that the technology of data storage and processing in nuclear medicine has reached a high degree of sophistication, as evidenced by many reports in the literature, the time has come to develop a perspective on the proper place of computers in nuclear medicine practice. The paper summarizes various uses of a dedicated computer (Nuclear Data Med II) at our two institutions and comments on its clinical utility. (author)

  8. Nuclear medicine : occupational health issues

    International Nuclear Information System (INIS)

    Rossleigh, M.

    1988-01-01

    The occupational health aspects of nuclear medicine are discussed. There is a lack of demonstrable biological effects from low level radiation. The radiation protection measures that are applied to ensure that staff are exposed to as low a level of radiation as is possible are outlined

  9. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... other diagnostic tests. Nuclear medicine imaging procedures use small amounts of radioactive materials – called radiotracers – that are typically injected into the bloodstream, inhaled or swallowed. The radiotracer travels through the area being examined and gives off energy in the ...

  10. Pulmonary explorations in nuclear medicine

    International Nuclear Information System (INIS)

    Beck, C.

    1987-01-01

    Ten years ago specialists in Nuclear Medicine from the South of France formed an Association called ACOMEN. The objectives were to create a permanent exchange of ideas between members and a close collaboration with physicians. The group objectives have led to a combination of efforts on the behalf of each one to clarify our techniques for physicians having recourse to this speciality as well as the various categories of students passing through the Nuclear Medicine Departments. Different groups within the ACOMEN were assigned to specific subjects. Each group was in charge of building the framework of a certain topic, which was then illustrated by selected documents contributed by all members. A slide collection, complete with an explanatory booklet is the final result of this collaboration. Thus anyone concerned in any way, with nuclear medicine, is able to quickly become familiar with the techniques of the speciality, to be aware of its possibilities and its limitations and to update his hnowledge. One realizes that the first theme selected was not the easiest; pulmonary radionuclide explorations are, as everyone knows, variable and even personalized. However, the choice was deliberate. The difficulty should stimulate those responsible for the other themes as well as the people working with them. There is already a slide collection available to anyone who wishes to learn about the use of nuclear medicine in the diagnosis of respiratory diseases [fr

  11. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... through the area being examined and gives off energy in the form of gamma rays which are detected by a special camera and computer to create images of the inside of your body. If you’re scheduled for a nuclear medicine exam, there are several things you can ...

  12. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available Toggle navigation Test/Treatment Patient Type Screening/Wellness Disease/Condition Safety En Español More Info Images/Videos About Us News Physician ... before abnormalities can be detected with other diagnostic tests. Nuclear medicine imaging procedures use small amounts of ...

  13. Quality control in nuclear medicine

    International Nuclear Information System (INIS)

    Kostadinova, I.

    2007-01-01

    Nuclear medicine comprises diagnosis and therapy of the diseases with radiopharmaceuticals. The ambition of all specialists in our country is their activity to reach European standards. In this connection, a Commission for external audit was formed to evaluate the quality of work in the centers of nuclear medicine. This Commission create a long-lasting programme based on the objective European criteria and the national standard of nuclear medicine, having in mind to increase quality of the work and the expert evaluation of activity in every center. The program comprises measures for quality control of instrumentation, radiopharmaceuticals, performed investigations, obtained results and the whole organization from the receiving of the isotopes to the results of the patients. The ambition is most of the centers to fulfill the requirements. As a conclusion it could be said that not only the quality of everyday nuclear medicine work is enough to increase the prestige of the specialty. It is also necessary we to have understanding expert and financial support from corresponding institutions, incl. Ministry of health for a delivery of a new, contemporary instrumentation with new possibilities. Thus it would be possible Bulgarian patients to reach the high technology apparatuses for an early functional diagnosis of the diseases and optimal treatment, which possibility have the patients from the developed countries. (author)

  14. Tomographic methods in nuclear medicine

    International Nuclear Information System (INIS)

    Ahluwalia, B.D.

    1989-01-01

    This book is a review of the various approaches to tomographic imaging that have been pursued in nuclear medicine. The evolution of single photon emission computed tomography (SPECT) is discussed in detail, and the major classes of instrumentation are represented. A section on positron emission tomography is also included, but is rather brief and may serve only as a general introduction

  15. Nuclear medicine at the crossroads

    International Nuclear Information System (INIS)

    Strauss, H.W.

    1996-01-01

    Many nuclear medicine procedures, originally developed more than 20 years ago, are now performed with new radiopharmaceuticals or instruments; it is therefore apposite to reappraise what we are doing and why we are doing it. The clinical utility of nuclear medicine is discussed with reference, by way of example, to gated blood pools scans and myocardial perfusion imaging; the importance of the referred population for the outcome of studies is stressed. Attention is drawn to the likelohood that the detection of ischemia would be enhanced by the administration of nitroglycerin prior to rest thallium injection. Emphasis is also placed on the increasing acceptance of dual-tracer studies. The significance of expression of p-glycoprotein by some tumors for sestamibi imaging is discussed, and advances in respect of fluorodeoxyglucose imaging are reviewed. The final section covers issues relating to the development of new procedures, such as the value of nuclear medicine in the detection and characterization of tissue oxygen levels and the possible future role of nuclear medicine in the management of sleeping and eating disorders. (orig.)

  16. Images compression in nuclear medicine

    International Nuclear Information System (INIS)

    Rebelo, M.S.; Furuie, S.S.; Moura, L.

    1992-01-01

    The performance of two methods for images compression in nuclear medicine was evaluated. The LZW precise, and Cosine Transformed, approximate, methods were analyzed. The results were obtained, showing that the utilization of approximated method produced images with an agreeable quality for visual analysis and compression rates, considerably high than precise method. (C.G.C.)

  17. Nuclear medicine software: safety aspects

    International Nuclear Information System (INIS)

    Anon.

    1989-01-01

    A brief editorial discusses the safety aspects of nuclear medicine software. Topics covered include some specific features which should be incorporated into a well-written piece of software, some specific points regarding software testing and legal liability if inappropriate medical treatment was initiated as a result of information derived from a piece of clinical apparatus incorporating a malfunctioning computer program. (U.K.)

  18. Radiation safety in nuclear medicine procedures

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Sang Geon; Kim, Ja Hae; Song, Ho Chun [Dept. of Nuclear Medicine, Medical Radiation Safety Research Center, Chonnam National University Hospital, Gwangju (Korea, Republic of)

    2017-03-15

    Since the nuclear disaster at the Fukushima Daiichi Nuclear Power Plant in 2011, radiation safety has become an important issue in nuclear medicine. Many structured guidelines or recommendations of various academic societies or international campaigns demonstrate important issues of radiation safety in nuclear medicine procedures. There are ongoing efforts to fulfill the basic principles of radiation protection in daily nuclear medicine practice. This article reviews important principles of radiation protection in nuclear medicine procedures. Useful references, important issues, future perspectives of the optimization of nuclear medicine procedures, and diagnostic reference level are also discussed.

  19. Radiation safety in nuclear medicine procedures

    International Nuclear Information System (INIS)

    Cho, Sang Geon; Kim, Ja Hae; Song, Ho Chun

    2017-01-01

    Since the nuclear disaster at the Fukushima Daiichi Nuclear Power Plant in 2011, radiation safety has become an important issue in nuclear medicine. Many structured guidelines or recommendations of various academic societies or international campaigns demonstrate important issues of radiation safety in nuclear medicine procedures. There are ongoing efforts to fulfill the basic principles of radiation protection in daily nuclear medicine practice. This article reviews important principles of radiation protection in nuclear medicine procedures. Useful references, important issues, future perspectives of the optimization of nuclear medicine procedures, and diagnostic reference level are also discussed

  20. Radionuclides for nuclear medicine: a nuclear physicists' view

    DEFF Research Database (Denmark)

    Cantone, M.; Haddad, F.; Harissopoulos, S.

    2013-01-01

    NuPECC (the Nuclear Physics European Collaboration Committee, an expert committee of the European Science Foundation) has the mission to strengthen European Collaboration in nuclear science through the promotion of nuclear physics and its trans-disciplinary use and application. NuPECC is currently...... working on a report on “Nuclear Physics for Medicine” and has set up a working group to review the present status and prospects of radionuclides for nuclear medicine. An interim report will be presented to seek comments and constructive input from EANM members. In particular it is investigated how nuclear...... physics Methods and nuclear physics facilities are supporting the development and supply of medical radionuclides and how this support could be further strengthened in future. Aspects that will be addressed: •In recent years, the reactor-based supply chain of 99Mo/99mTc generators was repeatedly...

  1. Quality assurance in nuclear medicine

    International Nuclear Information System (INIS)

    Kaul, A.

    1986-01-01

    'Quality Assurance in Nuclear Medicine' is the title of the English language original that has been translated into German. The manual very extensively deals with quality control of nuclear medical equipment. Tests are explained for checking radioactivity measuring devices, manual and automatic in-vitro sample measuring systems, in-vivo measuring systems with single or multiple detectors, rectlinear scanners, and gamma cameras, including the phantoms required for the methods. Other chapters discuss the quality control of radiopharmaceuticals, or the quality assurance in data recording and evaluation of results. Helpful comments on the organisation of quality assurance programms are given. The book is intended as a practical guide for introducing quality assurance principles in nuclear medicine in the Federal Republic of Germany. With 13 figs., 22 tabs [de

  2. Physics and radiobiology of nuclear medicine

    CERN Document Server

    Saha, Gopal B

    2013-01-01

    The Fourth Edition of Dr. Gopal B. Saha’s Physics and Radiobiology of Nuclear Medicine was prompted by the need to provide up-to-date information to keep pace with the perpetual growth and improvement in the instrumentation and techniques employed in nuclear medicine since the last edition published in 2006. Like previous editions, the book is intended for radiology and nuclear medicine residents to prepare for the American Board of Nuclear Medicine, American Board of Radiology, and American Board of Science in Nuclear Medicine examinations, all of which require a strong physics background. Additionally, the book will serve as a textbook on nuclear medicine physics for nuclear medicine technologists taking the Nuclear Medicine Technology Certification Board examination.

  3. 22. French language symposium on nuclear medicine

    International Nuclear Information System (INIS)

    1981-01-01

    The 80 papers presented in summary form at the Congress are given. These papers cover three main topics: broncho-pulmonary investigation with radioaerosols; role of nuclear medicine in pharmacokinetics; role of Nuclear Medicine in metabolic investigations [fr

  4. Evolution of nuclear medicine: a historical perspective

    International Nuclear Information System (INIS)

    Ahmed, A.; Kamal, S.

    1996-01-01

    The field Nuclear Medicine has Completed its 100 yeas in 1996. Nuclear medicine began with physics, expanded into chemistry and instrumentation, and then greatly influenced various fields of medicine. The chronology of the events that formulated the present status of nuclear medicine involves some of the great pioneers of yesterday like Becquerel, Curie, Joliot, Hevesy, Anger, Berson and Yallow. The field of nuclear medicine has been regarded as the bridge builder between various aspects of health care and within next 20 years, nuclear medicine enters a new age of certainty, in which surgery, radiation and chemotherapy will only be used when a benefit in certain to result from the treatment. (author)

  5. Essentials of nuclear medicine physics and instrumentation

    CERN Document Server

    Powsner, Rachel A; Powsner, Edward R

    2013-01-01

    An excellent introduction to the basic concepts of nuclear medicine physics This Third Edition of Essentials of Nuclear Medicine Physics and Instrumentation expands the finely developed illustrated review and introductory guide to nuclear medicine physics and instrumentation. Along with simple, progressive, highly illustrated topics, the authors present nuclear medicine-related physics and engineering concepts clearly and concisely. Included in the text are introductory chapters on relevant atomic structure, methods of radionuclide production, and the interaction of radiation with matter. Fu

  6. Introductory physics of nuclear medicine

    International Nuclear Information System (INIS)

    Chandra, R.

    1976-01-01

    This presentation is primarily addressed to resident physicians in nuclear medicine, as well as residents in radiology, pathology, and internal medicine. Topics covered include: basic review; nuclides and radioactive processes; radioactivity-law of decay, half-life, and statistics; production of radionuclides; radiopharmaceuticals; interaction of high-energy radiation with matter; radiation dosimetry; detection of high-energy radiation; in-vitro radiation detection; in-vivo radiation detection using external detectors; detectability or final contrast in a scan; resolution and sensitivity of a scanner; special techniques and instruments; therapeutic uses of radionuclides; biological effects of radiation; and safe handling of radionuclides

  7. Where is high technology taking nuclear medicine

    International Nuclear Information System (INIS)

    Veall, N.

    1985-01-01

    The question is posed as to whether high technology in nuclear medicine might lead to the nuclear medicine practitioner possibly finishing up working for the machine rather than the improvement of health care in its widest sense. A brief examination of some pros and cons of high technology nuclear medicine is given. (U.K.)

  8. Technetium in chemistry and nuclear medicine

    International Nuclear Information System (INIS)

    Deutsch, E.; Nicolini, M.; Wagner, H.N.

    1983-01-01

    This volume explores the potential of technetium radiopharmaceuticals in clinical nuclear medicine. The authors examine the capabilities of synthetic inorganic chemists to synthesize technetium radiopharmaceuticals and the specific requirements of the nuclear medicine practitioner. Sections cover the chemistry of technetium, the production of radiopharmaceuticals labeled with technetium, and the use of technetium radiopharmaceuticals in nuclear medicine

  9. A computerized system for control and management of radionuclide inventory: application in nuclear medicine

    International Nuclear Information System (INIS)

    Hoory, S.; Levy, I.M.; Moskowitz, G.; Bandyopadhyay, D.; Vaugeois, J.C.

    1982-01-01

    An interactive computerized system for radioisotope management and instantaneous inventory is reported. The system is capable of handling operations such as filing, nuclear imaging and disposing of various radionuclides. All radiopharmaceutical transactions are achieved with the aid of a Prime 300 mini-computer of 192K words of high speed semi-conductor memory and over 120 mega bytes of disk storage. The system automatically corrects for the appropriate decay, monitors and updates the storage file after every subsequent study. The performed study is recorded in a special file, together with the time and data retrieved from the computer's real time clock at the time of the entry. The system provides an organized and complete bookkeeping of all records concerning radionuclide transactions. It is found to be simple, efficient, highly versatile, and drastically reduces the time of operation and errors in handling the radioisotope inventory. (author)

  10. Integral-equation based methods for parameter estimation in output pulses of radiation detectors: Application in nuclear medicine and spectroscopy

    Science.gov (United States)

    Mohammadian-Behbahani, Mohammad-Reza; Saramad, Shahyar

    2018-04-01

    Model based analysis methods are relatively new approaches for processing the output data of radiation detectors in nuclear medicine imaging and spectroscopy. A class of such methods requires fast algorithms for fitting pulse models to experimental data. In order to apply integral-equation based methods for processing the preamplifier output pulses, this article proposes a fast and simple method for estimating the parameters of the well-known bi-exponential pulse model by solving an integral equation. The proposed method needs samples from only three points of the recorded pulse as well as its first and second order integrals. After optimizing the sampling points, the estimation results were calculated and compared with two traditional integration-based methods. Different noise levels (signal-to-noise ratios from 10 to 3000) were simulated for testing the functionality of the proposed method, then it was applied to a set of experimental pulses. Finally, the effect of quantization noise was assessed by studying different sampling rates. Promising results by the proposed method endorse it for future real-time applications.

  11. Quantitative Analysis in Nuclear Medicine Imaging

    CERN Document Server

    2006-01-01

    This book provides a review of image analysis techniques as they are applied in the field of diagnostic and therapeutic nuclear medicine. Driven in part by the remarkable increase in computing power and its ready and inexpensive availability, this is a relatively new yet rapidly expanding field. Likewise, although the use of radionuclides for diagnosis and therapy has origins dating back almost to the discovery of natural radioactivity itself, radionuclide therapy and, in particular, targeted radionuclide therapy has only recently emerged as a promising approach for therapy of cancer and, to a lesser extent, other diseases. As effort has, therefore, been made to place the reviews provided in this book in a broader context. The effort to do this is reflected by the inclusion of introductory chapters that address basic principles of nuclear medicine imaging, followed by overview of issues that are closely related to quantitative nuclear imaging and its potential role in diagnostic and therapeutic applications. ...

  12. Nuclear medicine in traumatology

    International Nuclear Information System (INIS)

    Spitz, J.

    2002-01-01

    Bone scintigraphy is a splendid tool to detect fractures by its high affinity to the newly built amorphous calcium phosphate of the callus. MRI on the other hand demonstrates anatomical details without radiation burden to the patient and has become the favourite tool of orthopediques and traumatologists. Nevertheless bone scintigraphy has kept its special indications - sometimes in addition to routine MRI. Main indications are the wholebody-investigation, the estimation of relative fracture age, unclear situations of pain, extraarticular ossifications, algodystrophy and the estimation of bone damage after polytrauma. If MRI is not available bone-scintigraphy covers the following indications: detection and exclusion of ischaemia and necrosis of bones, stress and insufficiency fractures, differentiation of soft tissue leasions from fractures and so called ''bone bruises''. i.e. damage to the bone layer immediately below the chondral surface of the joints. The same catalogue is valid, if there are technical problems in MRI (pacemaker-patient, risk of anesthesia in patient with claustrophobia or with adipositas per magna and metall artefacts in MRI reconstruction). Optimized technical procedures are essentials for efficient application of bone scintigraphy in traumatology (SPECT for the trunk and multiplanar views in extremities) as well as good anatomical knowledge and integrated interpretation of functional bone scans together with the morphological information's of ultrasound, X-Ray and even MRI. (orig.) [de

  13. Radiation protection in nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Volodin, V; Hanson, G P

    1993-12-31

    The goal of this Chapter is to give a general outline of the essential principles and procedures for radiation protection in a nuclear medicine department where radionuclides are used for diagnosis and therapy. More detailed recommendations regarding radiation protection in nuclear medicine are given in the publications of the International Commission on Radiation Protection (ICRP, publications 25, 57, 60) and in ILO/IAEA/WHO Manual on Radiation Protection in Hospitals and General Practice (Volume 2: Unsealed Sources, WHO, Geneva, 1975), on which this Chapter is based. This chapter is not intended to replace the above-mentioned international recommendations on radiation protection, as well as existing national regulations on this subject, but intended only to provide guidance for implementing these recommendations in clinical practice

  14. Radiation protection in nuclear medicine

    International Nuclear Information System (INIS)

    Volodin, V.; Hanson, G.P.

    1992-01-01

    The goal of this Chapter is to give a general outline of the essential principles and procedures for radiation protection in a nuclear medicine department where radionuclides are used for diagnosis and therapy. More detailed recommendations regarding radiation protection in nuclear medicine are given in the publications of the International Commission on Radiation Protection (ICRP, publications 25, 57, 60) and in ILO/IAEA/WHO Manual on Radiation Protection in Hospitals and General Practice (Volume 2: Unsealed Sources, WHO, Geneva, 1975), on which this Chapter is based. This chapter is not intended to replace the above-mentioned international recommendations on radiation protection, as well as existing national regulations on this subject, but intended only to provide guidance for implementing these recommendations in clinical practice

  15. Basic science of nuclear medicine

    International Nuclear Information System (INIS)

    Parker, R.P.; Taylor, D.M.; Smith, P.H.S.

    1978-01-01

    A book has been written presenting those aspects of physics, chemistry and related sciences which are essential to a clear understanding of the scientific basis of nuclear medicine. Part I covers the basic physics of radiation and radioactivity. Part II deals with radiation dosimetry, the biological effects of radiation and the principles of tracer techniques. The measurement of radioactivity and the principal aspects of modern instrumentation are presented in Part III. Those aspects of chemistry relevant to the preparation and use of radiopharmaceuticals are discussed in Part IV. The final section is concerned with the production of radionuclides and radiopharmaceuticals and with the practical aspects of laboratory practice, facilities and safety. The book serves as a general introductory text for physicians, scientists, radiographers and technicians who are entering nuclear medicine. (U.K.)

  16. Beijing nuclear medicine survey 2005: general information

    International Nuclear Information System (INIS)

    Geng Jianhua; Si Hongwei; Chen Shengzu

    2008-01-01

    Objective: To evaluate the status of nuclear medicine department in Beijing area. Methods: Staff, equipment and clinical applications of nuclear medicine departments in Beijing area during 2005 were evaluated by postal questionnaires. Results: Thirty nuclear medicine departments responded to our survey. In these departments, 321 staff, 141 doctors, 122 technicians, 7 physicists, 22 nurses and 29 other staff were employed; and 41 large imaging equipments, 37 SPECT, 3 PET, 1 PET-CT were equipped. During 2005, 88135 radionuclide imaging (84734 for SPECT, 3401 for PET), 462246 radioimmunoassay and 2228 radionuclide therapies (the most for Graves' disease, the second for thyroid cancer, the third for bone metastasis) were performed. For only 41.5% and 22.0% equipments the daily quality control (QC) and weekly QC were conducted. Conclusions Staff, equipments and activities of nuclear medicine department in Beijing were in a considerable scale, but did not balance among hospitals. Most departments should increase the number of physicists and the equipment QC procedures to improve the image quality. (authors)

  17. Nuclear medicine in developing countries

    International Nuclear Information System (INIS)

    Kremenchuzky, S.; Degrossi, O.J.

    1991-01-01

    The economic crisis through which developing countries are passing means that every field of endeavour must adapt to new realities imposed by each particular's country's situation. Public health is no exception, although it is obviously a priority field in view of the repercussions which social and economic phenomena can have on the health of a country's inhabitants. This article briefly considers ways in which nuclear medicine facilities in Argentina may be improved

  18. New procedures in nuclear medicine

    International Nuclear Information System (INIS)

    Spencer, R.P.

    1989-01-01

    The authors review the recent emergence of functional studies in nuclear medicine in this critical and informative text. The new procedures are presented in terms of their underlying physiology, indications, contraindications, methodology, results, interpretation and relationship to other evaluations. The volume includes discussions on the central nervous system, interventional studies, cardiac studies, bone densitometry, plus radiolabeled antibodies, radiolabeling of blood elements and flow and distribution

  19. Distributed nuclear medicine applications using World Wide Web and Java technology

    International Nuclear Information System (INIS)

    Knoll, P.; Hoell, K.; Koriska, K.; Mirzaei, S.; Koehn, H.

    2000-01-01

    At present, medical applications applying World Wide Web (WWW) technology are mainly used to view static images and to retrieve some information. The Java platform is a relative new way of computing, especially designed for network computing and distributed applications which enables interactive connection between user and information via the WWW. The Java 2 Software Development Kit (SDK) including Java2D API, Java Remote Method Invocation (RMI) technology, Object Serialization and the Java Advanced Imaging (JAI) extension was used to achieve a robust, platform independent and network centric solution. Medical image processing software based on this technology is presented and adequate performance capability of Java is demonstrated by an iterative reconstruction algorithm for single photon emission computerized tomography (SPECT). (orig.)

  20. Asian School of Nuclear Medicine

    International Nuclear Information System (INIS)

    Sundram, Felix X.

    2004-01-01

    The Asian School of Nuclear Medicine (ASNM) was formed in February 2003, with the ARCCNM as the parent body. Aims of ASNM: 1. To foster Education in Nuclear Medicine among the Asian countries, particularly the less developed ones. 2. To promote training of Nuclear Medicine Physicians in cooperation with government agencies, IAEA and universities and societies. 3. To assist in national and regional training courses, award continuing medical education (CME) points and provide regional experts for advanced educational programmes. 4. To work towards awarding of diplomas or degrees in association with recognized universities by distance learning and practical attachments, with examinations. The ASNM works toward a formal training courses leading to the award of a certificate in the long term. The most fundamental job of the ASNM remains the transfer of knowledge from the more developed countries to the less developed ones in the Asian region. The ASNM could award credit hours to the participants of training courses conducted in the various countries and conduct electronic courses and examinations. CME programmes may also be conducted as part of the regular ARCCNM meetings and the ASNM will award CME credit points for such activities

  1. Interventional studies in nuclear medicine

    International Nuclear Information System (INIS)

    Saha, G.B.; Swanson, D.P.; Hladik, W.B. III

    1987-01-01

    Pharmacological interventions in nuclear medicine studies have been in practice for a long time. The triiodothyronine (T/sub 3/) suppression, Thyroid-stimulating hormone (TSH) stimulation, and perchlorate discharge tests are common examples of well-established diagnostic interventional studies. In recent years, pharmacologic and physiologic interventions in other nuclear medicine procedures have drawn considerable attention. The primary purpose of these interventions is to augment, complement or, more often, differentiate the information obtained from conventional nuclear medicine diagnostic studies. Pharmacologic interventions involve the administration of a specific drug before, during, or after the administration of radiopharmaceutical for a given study. The change in information due to intervention of the drug offers clues to differentiating various disease conditions. These changes can be brought about by physiologic interventions also, e.g., exercise in radionuclide ventriculography. In the latter interventions, the physiologic function of an organ is enhanced or decreased by physical maneuvers, and the changes observed can be used to differentiate various disease conditions

  2. Nuclear Medicine in Pediatric Cardiology.

    Science.gov (United States)

    Milanesi, Ornella; Stellin, Giovanni; Zucchetta, Pietro

    2017-03-01

    Accurate cardiovascular imaging is essential for the successful management of patients with congenital heart disease (CHD). Echocardiography and angiography have been for long time the most important imaging modalities in pediatric cardiology, but nuclear medicine has contributed in many situations to the comprehension of physiological consequences of CHD, quantifying pulmonary blood flow symmetry or right-to-left shunting. In recent times, remarkable improvements in imaging equipments, particularly in multidetector computed tomography and magnetic resonance imaging, have led to the progressive integration of high resolution modalities in the clinical workup of children affected by CHD, reducing the role of diagnostic angiography. Technology has seen a parallel evolution in the field of nuclear medicine, with the advent of hybrid machines, as SPECT/CT and PET/CT scanners. Improved detectors, hugely increased computing power, and new reconstruction algorithms allow for a significant reduction of the injected dose, with a parallel relevant decrease in radiation exposure. Nuclear medicine retains its distinctive capability of exploring at the tissue level many functional aspects of CHD in a safe and reproducible way. The lack of invasiveness, the limited need for sedation, the low radiation burden, and the insensitivity to body habitus variations make nuclear medicine an ideal complement of echocardiography. This is particularly true during the follow-up of patients with CHD, whose increasing survival represent a great medical success and a challenge for the health system in the next decades. Metabolic imaging using 18 FDG PET/CT has expanded its role in the management of infection and inflammation in adult patients, particularly in cardiology. The same expansion is observed in pediatric cardiology, with an increasing rate of studies on the use of FDG PET for the evaluation of children with vasculitis, suspected valvular infection or infected prosthetic devices. The

  3. Application of nuclear medicine methods for diagnosis of urolithiasis and its complications

    International Nuclear Information System (INIS)

    Hadzhiyska, V.

    2012-01-01

    The most common complications of urolithiasis are obstructive nephropathy and pyelonephritis, which often lead to irreversible consequences for the affected kidney. For the diagnosis is not sufficient just to visualize the stone, but also to evaluate the extent of functional changes in renal parenchyma, which will determine the type of therapeutic approach. The most common diagnostic algorithm of imaging methods in the diagnosis of urolithiasis includes ultrasound, X-ray overview and intravenous urography. Less commonly are performed CT, renal scintigraphy and retrograde urography and others. Problems in application of that algorithm are mainly related to incorrect localization of stones and difficulties to assess its effects on renal function. Dynamic renal scintigraphy (DRS) and its variety the diuretic scintigraphy is an established method for assessing the functional status of parenhima and drainage disorders of the kidney in renal colic and long standing hydronephrosis. Advantages of the method is rapid, accurate and noninvasive determination of the renal parenchyma and function, urodynamics of upper urinary tract, and the ability to present the relative percentage contribution of each kidney in total renal function. DRS is characterized by precise quantitative results, lack of bias and low radiation dose. However, recently in the literature we found some contradictory views on the application protocol and the importance of diuretic renal scintigraphy in the evaluation of renal obstruction. Moreover, there are some different viewpoints about the exact location of DRS in the diagnostic algorithm of patients with urolithiasis. In could be summarized that there are various imaging methods which provide extensive diagnostic capabilities in diagnoses of urolithiasis and its complications. Nevertheless, an express and complex method that combine functional and morphological data and provides comprehensive and reliable information hasn't been described yet. (authors)

  4. A manual of nuclear medicine procedures

    International Nuclear Information System (INIS)

    Das, B.K.; Noreen Norfaraheen Lee Abdullah

    2012-01-01

    Nuclear medicine is a fast growing specialty. The procedures provide quantitative parameters of organ functions required for modern practice of medicine. With the development of new machines and increased application of computer software, the procedures are under continuous change. Some procedures have become outdated or redundant while new methods have been introduced to enhance the quality of information obtained from a particular application. Although there are a few books published abroad to inform doctors and technical staff about the procedures, a comprehensive source to give quick information about how different test are performed, particularly the new developments and the expected outcome both in normal and abnormal cases has been a long felt need. The physician ordering a Nuclear Medicine test also needs to know what patient preparations are required for optimal results, how to satisfy the queries of the patient particularly in respect of radiation exposure which sometimes can be a major concern of the patient. This manual has been prepared not only to describe technical details of various procedures that are currently practiced in Nuclear Medicine, but also to provide quick information for the doctors and health care personnel on how to inform the patients about the investigation for which they are being referred and how to interpret the results. Since there is no such comprehensive book published yet in Asia including South-East Asia, it is likely to be in great demand in the region. All students of Master Degree, M.D., DRM, DMRIT, M.Sc. (Nuclear Medicine) and technologists already working in various diagnostic centers will likely buy this book. General practitioners and specialists who refer patients for different radioisotope investigations may find this book useful for quick reference. (author)

  5. Nuclear Medicine imaging of infection and inflammation Part 3: Clinical applications

    International Nuclear Information System (INIS)

    Gnanasegaran, G.; Croasdale, J.; Buscombe, J.R.

    2005-01-01

    Prompt localization of infection sites is essential for initiating appropriate therapeutic measures. There have been major advances in the management of patients suffering from infective and/or inflammatory disorders as a result of introduction of newer drugs with high sensitivity and specificity. However diagnosis of infection / inflammation still remains a major clinical problem. Although the typical signs of infection and inflammation are useful in localizing the pathology at superficial sites, infection and inflammation of internal structures are often difficult to localize without the aid of imaging procedures. Radionuclide imaging is an important diagnostic tool for the evaluation of patho-physiological processes of infection and inflammation. A spectrum of radiopharmaceuticals and a number of imaging protocols have been used in clinical practice. However every method differs in its potential to gather information at the cellular and molecular level. This review addresses some of the applications of radionuclide infection imaging procedures in musculoskeletal system, lymphatic system, in immunocompromised patients and in patients suffering from fever of unknown origin. (author)

  6. In vivo studies. In vivo nuclear medicine

    International Nuclear Information System (INIS)

    Syrota, A.; CEA, 91 - Orsay

    1997-01-01

    A historical review of the use of radioelements for biological applications and nuclear medicine is presented: planar gamma-scintigraphy, invented in 1957, which gives planar projections of the radioactivity distribution in an organ; tomography, which gives sections of an organ and reconstructed three-dimensional images; positron emission tomography, invented in the 70's, gives brain section images with carbon 11, nitrogen 13 and oxygen 15. Coupled utilization of these techniques with other functional image systems such as nuclear magnetic resonance, enables simultaneous anatomic and functional information such as cognitive functions and cerebral localizations

  7. Body contour measurements by conoscopy: application in nuclear medicine, study of feasibility

    International Nuclear Information System (INIS)

    Scheiber, C.; Musse, O.; Mallet, Y.; Sirat, G.

    1997-01-01

    The aim of this study was to obtain a precise mapping of the human body contours as viewed by the gamma camera during acquisition for pathological focus detection and as intermediary in the fusion with morphological images sources (CT, IRM, US). The measurement of the human body contours, making use of a telemeter system, was proposed by O. Peria (Ph.D Thesis, University of Grenoble) by using a laser telemeter and then structured-light sources. We proposed utilization of a non-coherent interferometer, the conoscope developed by G. Sirat, coupled to an electro-mechanical sweeping system mounted on the gamma camera rack. The first tests realized with a slow prototype (3 pt/s), have allowed the recording of visage contours (a profile obtained by angular rotation of the camera (10 deg.) on an (Elscint, Haifa) Helix gamma camera). For this experiment the voluntary subject has worn protection spectacles (the light source being a laser of 1 mW). Among the advantages of this compact system (14 x 10 x 15 cm) we stress: a) a high precision (0.2 mm); b) being installed on the rack, the calibration procedures are simplified and their shifts are potentially reduced; c) the procedures of intra-modality image matching is simplified; d) an integrated fast electronic circuitry (DSP) allows to exploit directly, in real time if necessary, the obtained results (x,y,z coordinates of the studied point). We considered that by its precision, its insensitivity to luminous environment conditions and its integration with the turning gamma camera, the system deserves to be evaluated for application in medical imaging. This system as other intermediate captors, using body contours, allows the superimposing of data, other than the image data, what helps the stereotaxic localization

  8. Pulmonary nuclear medicine: Techniques in diagnosis of lung disease

    International Nuclear Information System (INIS)

    Atkins, H.L.

    1984-01-01

    This book presents papers on the application of nuclear medicine to the diagnosis of lung diseases. Topics considered include lung physiology and anatomy, radiopharmaceuticals in pulmonary medicine, pulmonary embolism, obstructive pulmonary disease, diffuse infiltrative lung disease, pneumoconioses, tumor localization scans in primary lung tumors, the interactions of heart diseases and lung diseases on radionuclide tests of lung anatomy and function, radionuclide imaging in pediatric lung diseases, and future possibilities in pulmonary nuclear medicine

  9. Nuclear medicine in childhood tumours

    International Nuclear Information System (INIS)

    Hoefnagel, C.A.

    2004-01-01

    Full text: In recent years the contribution of nuclear medicine has been of increasing interest to paediatric oncology, in particular in imaging for diagnosis, staging and follow-up, in quantitative function analysis of organs at risk during oncological therapy, as well as in radionuclide therapy. For tumour imaging a great number of tumour-seeking radiopharmaceuticals are available, exploiting various metabolic and biological properties of individual tumours; several of these agents can also be applied for radionuclide therapy. More recent tracers allow the characterization of tumours, highlighting features like hormone receptors, hypoxia, MDR and apoptosis. New techniques in paediatric oncology include PET and probe-guided surgery. As a functional modality, nuclear medicine is well suited to monitor the function of organs at risk during treatment in paediatric oncology, in particular cardiac, pulmonary, renal and salivary gland function. A summary of applications and major Indications will be presented. Osteosarcoma: In differentiated osteosarcoma bone scintigraphy/SPECT using 99m Tc-diphosphonate may, as a result of Its targeting the tumour-produced osteoid, visualize not only the primary bone tumour and skeletal metastases, but also the extraosseous metastases. For preoperative therapy nd palliation of metastases beta-emitting bone-seeking agents, such as 89 Sr-chloride, 186 Re-HEDP and 153 Sm-EDTMP, are available. Lymphoma: 67 Ga-citrate has been used for decades in the detection, staging and follow up of lymphoma, as well as for early recognition of response to therapy. 201 TI-chloride scintigraphy/SPECT and PET using 18 F-deoxyglucose can also be used for this purpose. 99m Tc- sestamibi and 99m Tc-tetrofosmin are associated with p-glycoprotein, playing a role in multidrug resistance. In adults with recurrent non Hodgkin lymphoma treatment with 131 l- or 90 Y labelled anti-CD20 antibodies is highly effective. Thyroid carcinoma. 201 TI-chloride scintigraphy

  10. Radiochemistry in nuclear medicine. Radiopharmaceuticals

    International Nuclear Information System (INIS)

    Samochocka, K.

    1999-01-01

    Radionuclides and radiopharmaceuticals play a kay role in nuclear medicine, both in diagnostics and therapy. Incorporation of radionuclides into biomolecules, and syntheses of radiolabelled compounds of high biological selectivity are a task for radiochemists working in the multidisciplinary field of radiopharmaceutical chemistry. The most commonly used radionuclide, 99m Tc, owes this popularity to its both nearly ideal nuclear properties in respect to medical imaging, and availability from inexpensive radionuclide generators. Also numerous other radionuclides are widely used for medical imaging and therapy. Labelling of biomolecules with radioiodine and various positron emitters is getting increasingly important. This review describes some chemical and radiochemical problems we meet while synthesizing and using 99m Tc-radiopharmaceuticals and radioiodine-labelled biomolecules. Also represented are the recent developments in the design and use of the second generation radiopharmaceuticals based on bifunctional radiochelates. Several principal routes of fast chemical synthesis concerning incorporation of short-lived positron emitters into biomolecules are outlined as well. The search for chemical structures of high biological selectivity, which would be activated by slow neutrons, is related to the method of Neutron Capture Therapy, an interesting option in nuclear medicine. (author)

  11. The state of the art in diagnostic nuclear medicine

    International Nuclear Information System (INIS)

    Scott, A.M.; University of Melbourne, VIC

    2001-01-01

    Recent improvements in the understanding of the physiologic and biologic mechanisms of health and disease have led to an expansion of nuclear medicine applications both in clinical studies and research. Advances in radiopharmaceutical development, instrumentation and computer processing have resulted in the implementation of Positron Emission Tomography for clinical studies, and improved treatments with radiopharmaceuticals particularly in cancer patients. There has also been an dramatic increase in the techniques available with nuclear medicine to detect and measure cellular biologic events in-vivo, which have important implications in clinical and basic science research. Nuclear medicine studies provide unique information on human physiology and remain an integral part of clinical medicine practice

  12. The state of the art in nuclear medicine

    International Nuclear Information System (INIS)

    Scott, A.M.

    1999-01-01

    Recent improvements in the understanding of the physiologic and biologic mechanisms of health and disease have led to an expansion of nuclear medicine applications both in clinical studies and research. Advances in radiopharmaceutical development, instrumentation and computer processing have resulted in the implementation of Positron Emission Tomography for clinical studies, and improved treatments with radiopharmaceuticals particularly in cancer patients. There has also been a dramatic increase in the techniques available with nuclear medicine to detect and measure cellular biologic events in-vivo, which have important implications in clinical and basic science research. Nuclear medicine studies provide unique information on human physiology and remain an integral part of clinical medicine practice

  13. Scandium complexes: physico-chemical study and evaluation of stability in vitro and in vivo for nuclear medicine application

    International Nuclear Information System (INIS)

    Kerdjoudj, Rabha

    2014-01-01

    Among the different isotopes of Scandium that can be used in nuclear medicine may be mentioned the 47 Sc and 44 Sc. The first decays by emitting an electron associated with a 159 keV gamma can thus be used either for radiotherapy or TEMP imaging. The 44 Sc (3.97 h) decays in 94.27% in case by emitting a positron, with a γ photon energy equal to 1.157 MeV. This isotope is then an ideal candidate for applications in PET imaging. Currently, the Cyclotron of high energy and high intensity ARRONAX produce 44 Sc and co-produces the isomeric state the 44m Sc (2.44 d). The 44m Sc has properties (E(γ) = 270 keV, 98.8%), which allows to consider its use as a potential in vivo generator. Previous work had demonstrated that the DOTA ligand is most suitable and stable for Sc. This thesis aims; make in evidence the feasibility of the in vivo 44m / 44 Sc generator. Initially a procedure was optimized and validated for the production of 44m / 44 Sc with a high specific activity and chemical purity. Radiolabeling of DOTA conjugated peptides was then developed and optimized. Theoretical and experimental studies have been performed in order to demonstrate the feasibility of 44m / 44 Sc as a potential in vivo generator. Finally, in vitro stability studies on radiolabeled 44m / 44 Sc complexes were performed, followed by biodistribution studies and PET imaging. (author)

  14. Radiation, ionization, and detection in nuclear medicine

    International Nuclear Information System (INIS)

    Gupta, Tapan K.

    2013-01-01

    Up-to-date information on a wide range of topics relating to radiation, ionization, and detection in nuclear medicine. In-depth coverage of basic radiophysics relating to diagnosis and therapy. Extensive discussion of instrumentation and radiation detectors. Detailed information on mathematical modelling of radiation detectors. Although our understanding of cancer has improved, the disease continues to be a leading cause of death across the world. The good news is that the recent technological developments in radiotherapy, radionuclide diagnostics and therapy, digital imaging systems, and detection technology have raised hope that cancer will in the future be combatted more efficiently and effectively. For this goal to be achieved, however, safe use of radionuclides and detailed knowledge of radiation sources are essential. Radiation, Ionization, and Detection in Nuclear Medicine addresses these subjects and related issues very clearly and elaborately and will serve as the definitive source of detailed information in the field. Individual chapters cover fundamental aspects of nuclear radiation, including dose and energy, sources, and shielding; the detection and measurement of radiation exposure, with detailed information on mathematical modelling; medical imaging; the different types of radiation detector and their working principles; basic principles of and experimental techniques for deposition of scintillating materials; device fabrication; the optical and electrical behaviors of radiation detectors; and the instrumentation used in nuclear medicine and its application. The book will be an invaluable source of information for academia, industry, practitioners, and researchers.

  15. Radiation, ionization, and detection in nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Gupta, Tapan K. [Radiation Monitoring Devices Research, Nuclear Medicine, Watertown, MA (United States)

    2013-08-01

    Up-to-date information on a wide range of topics relating to radiation, ionization, and detection in nuclear medicine. In-depth coverage of basic radiophysics relating to diagnosis and therapy. Extensive discussion of instrumentation and radiation detectors. Detailed information on mathematical modelling of radiation detectors. Although our understanding of cancer has improved, the disease continues to be a leading cause of death across the world. The good news is that the recent technological developments in radiotherapy, radionuclide diagnostics and therapy, digital imaging systems, and detection technology have raised hope that cancer will in the future be combatted more efficiently and effectively. For this goal to be achieved, however, safe use of radionuclides and detailed knowledge of radiation sources are essential. Radiation, Ionization, and Detection in Nuclear Medicine addresses these subjects and related issues very clearly and elaborately and will serve as the definitive source of detailed information in the field. Individual chapters cover fundamental aspects of nuclear radiation, including dose and energy, sources, and shielding; the detection and measurement of radiation exposure, with detailed information on mathematical modelling; medical imaging; the different types of radiation detector and their working principles; basic principles of and experimental techniques for deposition of scintillating materials; device fabrication; the optical and electrical behaviors of radiation detectors; and the instrumentation used in nuclear medicine and its application. The book will be an invaluable source of information for academia, industry, practitioners, and researchers.

  16. Converting energy to medical progress [nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-04-01

    For over 50 years the Office of Biological and Environmental Research (BER) of the United States Department of Energy (DOE) has been investing to advance environmental and biomedical knowledge connected to energy. The BER Medical Sciences program fosters research to develop beneficial applications of nuclear technologies for medical diagnosis and treatment of many diseases. Today, nuclear medicine helps millions of patients annually in the United States. Nearly every nuclear medicine scan or test used today was made possible by past BER-funded research on radiotracers, radiation detection devices, gamma cameras, PET and SPECT scanners, and computer science. The heart of biological research within BER has always been the pursuit of improved human health. The nuclear medicine of tomorrow will depend greatly on today's BER-supported research, particularly in the discovery of radiopharmaceuticals that seek specific molecular and genetic targets, the design of advanced scanners needed to create meaningful images with these future radiotracers, and the promise of new radiopharmaceutical treatments for cancers and genetic diseases.

  17. Converting energy to medical progress [nuclear medicine

    International Nuclear Information System (INIS)

    2001-01-01

    For over 50 years the Office of Biological and Environmental Research (BER) of the United States Department of Energy (DOE) has been investing to advance environmental and biomedical knowledge connected to energy. The BER Medical Sciences program fosters research to develop beneficial applications of nuclear technologies for medical diagnosis and treatment of many diseases. Today, nuclear medicine helps millions of patients annually in the United States. Nearly every nuclear medicine scan or test used today was made possible by past BER-funded research on radiotracers, radiation detection devices, gamma cameras, PET and SPECT scanners, and computer science. The heart of biological research within BER has always been the pursuit of improved human health. The nuclear medicine of tomorrow will depend greatly on today's BER-supported research, particularly in the discovery of radiopharmaceuticals that seek specific molecular and genetic targets, the design of advanced scanners needed to create meaningful images with these future radiotracers, and the promise of new radiopharmaceutical treatments for cancers and genetic diseases

  18. Programmatic activities of IAEA in nuclear medicine

    International Nuclear Information System (INIS)

    Padhy, A.K.

    2004-01-01

    Nuclear medicine is high-tech medicine. Nevertheless, it is essential for addressing important health problems of people living in developing countries also. Not only is it sometimes expensive to start with, it also involves a lot of technical know-how, requiring transfer of technology from developed to the developing countries. The rapid development of nuclear medicine, of sophisticated instrumentation and radiopharmaceuticals has resulted in an enormous increase in costs and in the need for maintaining quality. These constitute a challenge and a venture when promoting nuclear medicine globally and particularly in developing countries. No other international organization except IAEA has any specific mandate for application of nuclear energy in the area of human health. WHO has no specific programin nuclear medicine, hence the importance of IAEA's involvement. The IAEA has, ever since its inception, given high priority to enhancing the awareness and capabilities of developing member states to employ nuclear technology for health care and medical research. Much of the Agency promoted research in nuclear medicine is delivered through the so called co-ordinated research projects (CRPs). The CRPs are normally organised as multi-center, prospective studies so that large volume of scientific data could be generated in a short period of 18-24 months. The research is normally done within an operational frame work, established and co-ordinated by the IAEA. The reason for this is that the results can be compared despite site or country specific differences. The methods and materials used for such studies usually conform to a predetermined standard. The protocols for various investigations, criteria for patient selection, mode of arriving at a final diagnosis and analysis of data from these multi-center studies are normally agreed upon by the Chief Scientific Investigators from each participating institution and the IAEA prior to the start of the actual work programme. The

  19. Is nuclear medicine really safe?

    International Nuclear Information System (INIS)

    Colas-Linhart, N.

    2000-01-01

    How to evaluate the benefit-risks ratio of scintigraphies? In nuclear medicine, radiation absorbed dose estimates at whole body or organ levels are very low. Nevertheless, at cellular level, there are both heterogeneity of distribution and heterogeneity of radiation emission. Consequently, absorbed doses at cellular level are often calculated. These absorbed dose values are surprising, even disturbing or not interpretable. In the present study, we have searched the biological consequences at the cellular level, radioinduced by two radiopharmaceuticals labelled with 99m Tc: human serum albumin microspheres and HMPAO, studying the cellular ultrastructure, over expression of p53 and scoring instable chromosomal aberrations. (author)

  20. Distribution of nuclear medicine service in Brazil

    International Nuclear Information System (INIS)

    Silva, Ana Carolina Costa da; Duarte, Alessandro; Santos, Bianca Maciel dos

    2011-01-01

    The Brazil does not posses a good distribution of nuclear medicine service por all his territory. This paper shows the difference among country regions as far the number of clinics of nuclear medicine as is concerning, and also doctors licensed in the area and radioprotection supervisors, both licensed by the Brazilian Nuclear Energy Commission (CNEN)

  1. Teaching of nuclear medicine at medical faculties

    International Nuclear Information System (INIS)

    Dienstbier, Z.

    1987-01-01

    The teaching of nuclear medicine at medical faculties in the CSSR is analyzed. It is shown that the teaching conditions are different at the individual faculties of medicine and the respective conditions are exemplified. (author). 4 tabs

  2. Equipment used in nuclear medicine

    International Nuclear Information System (INIS)

    Das, B.K.; Noreen Norfaraheen Lee Abdullah

    2012-01-01

    Detection of radiation is the common purpose of all equipment's and instruments used in radioisotope laboratories. The first and most important instrument that was used in nuclear medicine was Geiger tube developed by H.W. Geiger as early in 1908. He in association with Mueller developed the so called Geiger-Muller tube (GM tube) which could be used to detect beta and gamma radiations. In spite of its severe limitations, GM tube remained the only external counting device until 1949. In 1948, Kallman reported that the scintillations can be detected and amplified with the help of photomultiplier tubes (PMTs). In comparison with gas filled detectors, scintillation detectors have two principal advantages that augment their use in nuclear medicine. Firstly, they are capable of much higher counting rates because of fast resolving times and secondly, because they are much more efficient for gamma ray detection. The scintillation detector is the most basic block of any modern radioisotope detection instrument like rate meter, counter, scanner, gamma camera or single photon emission computed tomography. (author)

  3. Radiation dosimetry in nuclear medicine

    International Nuclear Information System (INIS)

    Stabin, M.G.; Tagesson, M.; Ljungberg, M.; Strand, S.E.; Thomas, S.R.

    1999-01-01

    Radionuclides are used in nuclear medicine in a variety of diagnostic and therapeutic procedures. A knowledge of the radiation dose received by different organs in the body is essential to an evaluation of the risks and benefits of any procedure. In this paper, current methods for internal dosimetry are reviewed, as they are applied in nuclear medicine. Particularly, the Medical Internal Radiation Dose (MIRD) system for dosimetry is explained, and many of its published resources discussed. Available models representing individuals of different age and gender, including those representing the pregnant woman are described; current trends in establishing models for individual patients are also evaluated. The proper design of kinetic studies for establishing radiation doses for radiopharmaceuticals is discussed. An overview of how to use information obtained in a dosimetry study, including that of the effective dose equivalent (ICRP 30) and effective dose (ICRP 60), is given. Current trends and issues in internal dosimetry, including the calculation of patient-specific doses and in the use of small scale and microdosimetry techniques, are also reviewed

  4. Dementia and rural nuclear medicine

    International Nuclear Information System (INIS)

    Cowell, S.F.; Davison, A.; Logan-Sinclair, P.; Sturt University, Dubbo, NSW; Greenough, R.

    2003-01-01

    Full text: The rapid increase in dementia is directly related to the growing number of aged people in developed countries, such as Australia. This increase heightens the need for accurate dementia diagnosis to ensure treatment resources are appropriately allocated. However, current diagnostic methods are unable to determine specific dementia types limiting the effectiveness of many care plans. The lack of specialist resources in rural Australian communities presents nuclear medicine with an opportunity to make a significant impact on the management of this disease. This investigation aimed to identify how SPECT perfusion imaging could maximise its role in the management of dementia in a rural New South Wales setting. The study reviewed all Technetium 99m HMPAO SPECT brain studies over a three-year period. This included a medical record audit, review of all diagnostic imaging reports and an analysis of referral patterns. The results of this study provide compelling evidence that, even in a rural setting, brain SPECT, in conjunction with neuropsychological testing, offers high accuracy in determining the presence and type of dementia. In addition, the study found more than 30% of referrers had no training in SPECT, emphasising the importance of ensuring that brain SPECT reports, in a rural setting, educate and specify to referrers the significance and exact disease type found in the study. Copyright (2003) The Australian and New Zealand Society of Nuclear Medicine Inc

  5. Metabolic radiopharmaceutical therapy in nuclear medicine

    International Nuclear Information System (INIS)

    Reguera, L.; Lozano, M. L.; Alonso, J. C.

    2016-01-01

    In 1986 the National Board of Medical Specialties defined the specialty of nuclear medicine as a medical specialty that uses radioisotopes for prevention, diagnosis, therapy and medical research. Nowadays, treatment with radiopharmaceuticals has reached a major importance within of nuclear medicine. The ability to treat tumors with radiopharmaceutical, Radiation selective therapy has become a first line alternative. In this paper, the current situation of the different therapies that are sued in nuclear medicine, is reviewed. (Author)

  6. Digital filtering of scintigrams and an investigation into the application of the fresnel zone plate in nuclear medicine

    International Nuclear Information System (INIS)

    Berg, C.J.M. van den

    1976-01-01

    By lack of media large enough to obtain a gamma-lens gamma radiation imaging detectors are based on collimation by absorbence. At present, routine static studies in Nuclear Medicine generally make use of gamma cameras equiped with conventional collimators of limited resolution characterized by their impulse response function. Two methods of improvement of scintigraphic imaging are investigated in this thesis: i) Digital filtering of scintigrams obtained with a conventional collimator (Chapter III); ii) Use of alternative collimation techniques i.e. the use of coded apertures, especially of Zone Plates

  7. Nuclear medicine and its radiological protection in China

    International Nuclear Information System (INIS)

    Wu, J.

    2001-01-01

    The China Society of Nuclear Medicine was established on 27 May 1980. Since then, nuclear medicine in clinical diagnosis and therapy has been developed rapidly in China. So far there are more than 4000 members of the Society, and more than 350 sets of SPECT and 12 sets of PET have been installed and are busily running in clinic nowadays and about 1 million patients with different types of diseases have obtained nuclear medicine imaging examinations per year. Concerning the nuclear medicine therapy, a lot of patients with many types of diseases obtained benefit from radioisotope therapy. Accordingly, several Policies and Regulations have been enacted by the Government for the radiological protection. Furthermore, a special book titled 'Standardization in Diagnostic and Therapeutic Nuclear Medicine' has been promulgated in June, 1997 by the Health Administration of People's Republic of China, and this book is distributed to almost every nuclear medicine physician and technician in China for their reference in routine nuclear medicine work or research. In this book three parts of the contents are covered: Policies and Regulations for the radiological protection, basic knowledge and clinical nuclear medicine applications. (author)

  8. Quality policy at nuclear medicine services

    International Nuclear Information System (INIS)

    Gil Martinez, Eduardo Manuel; Jimenez, Tomas

    2007-01-01

    In the present text we comment about a Quality Policy model to establish in a Nuclear Medicine Service. The need for a strict control in every process that take place in a Nuclear Medicine Service, requires of an exact planification in terms of Quality Policy, specific to the real needs of every Service. Quality Policy must be a live Policy, with capability of changes and must be known for every workers in a Nuclear Medicine Service. Although the 'model' showed in this text is concret for a specific Service type, it must be extrapolated to any Nuclear Medicine Service with the necessary changes (au)

  9. Photon energy readings in OSL dosimeter filters: an application to retrospective dose estimation for nuclear medicine workers.

    Science.gov (United States)

    Villoing, Daphnée; Kitahara, Cari M; Passmore, Christopher; Simon, Steven L; Yoder, R Craig

    2018-06-19

    This work investigates the applicability of using data from personal monitoring dosimeters to assess photon energies to which medical workers were exposed. Such determinations would be important for retrospective assessments of organ doses to be used in occupational radiation epidemiology studies, particularly in the absence of work history or other information regarding the energy of the radiation source. Monthly personal dose equivalents and filter ratios under two different metallic filters contained in the Luxel+® dosimeter were collected from Landauer, Inc. from 19 nuclear medicine (NM) technologists employed by three medical institutions, the institution A only performing traditional NM imaging (primarily using 99mTc) and institutions B and C also performing positron emission tomography (PET, using 18F). Calibration data of the Luxel+® dosimeter for various X-ray spectra were used to establish ranges of filter ratios from 1.1 to 1.6 for 99mTc and below 1.1 for 18F. Median filter ratios were 1.33 (Interquartile range (IQR), 0.15) for institution A, 1.08 (IQR, 0.16) for institution B, and 1.08 (IQR, 0.14) for institution C. The distributions of these filter ratios were statistically-significantly different between the institution A only performing traditional NM imaging and institutions B and C also performing PET imaging. In this proof-of-concept study, filter ratios from personal dosimeters were used to assess differences in photon energies to which NM technologists were exposed. Dosimeters from technologists only performing traditional NM procedures mostly showed Al/Cu filter ratios above 1.2, those likely performing only PET in a particular month had filter ratios below 1.1, and those which showed filter ratios between 1.1 and 1.2 likely came from technologists rotating between traditional NM and PET imaging in the same month. These results suggest that it is possible to distinguish technologists who

  10. Radiation protection on nuclear medicine services

    International Nuclear Information System (INIS)

    Anon

    2000-01-01

    Nuclear medicine is a sector of the medicine that studies and applies radionuclide in diagnosis and therapy. Nuclear medicine is a very specific area of the medicine, making use of non-sealed radioactive sources which are prescribed to the patient orally or are injected. Special procedures in radiation protection are required in nuclear medicine to manipulate these kind of sources and to produce technetium-99m through molybdenum generator. The present paper addresses the them radiation protection in a Nuclear Medicine Department (NMD), showing the main requirements of the CNEN- National Commission of Nuclear Energy and the Public Health. Radiation protection procedures adopted in assembling a NMD, as well the daily techniques for monitoring and for individual dosimetry are discussed. Past and present analyses in a level of radiation protection are presented. (author)

  11. Radionuclides for nuclear medicine: a nuclear physicists' view

    Czech Academy of Sciences Publication Activity Database

    Cantone, M.; Haddad, F.; Harissopoulos, S.; Jensen, M.; Jokinen, A.; Koster, U.; Lebeda, Ondřej; Ponsard, B.; Ratzinger, U.; Stora, T.; Tarkanyi, F.; Van Duppen, P.

    2013-01-01

    Roč. 40, 2 Supplement (2013), S257-S257 ISSN 1619-7070. [Annual Congress of the European Association of Nuclear Medicine (EANM). 19.10.2013-23.10.2013, Lyon] Institutional support: RVO:61389005 Keywords : nuclear physics for medicine * EANM * medical radionuclides Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders

  12. Nuclear applications in life sciences

    International Nuclear Information System (INIS)

    Uenak, P.

    2009-01-01

    Radioactivity has revolutionized life sciences during the last century, and it is still an indispensable tool. Nuclear Medicine, Radiation Biology and Radiotherapy, Dosimetry and Medical Radiation Physics, Nutrition and Environmental Problems Relevant Health are significant application fields of Nuclear Sciences. Nuclear medicine today is a well established branch of medicine. Radionuclides and radiopharmaceuticals play a key role both in diagnostic investigations and therapy-Both cyclotron and reactor produced radionuclides find application, the former more in diagnostic studies and the latter in therapy. New therapy applications such as bor neutron therapy are increasing by time together with the technological improvements in imaging systems such as PET and SPECT. Radionuclides and radiopharmaceuticals play important role in both therapy and imaging. However cyclotron produced radionuclides have been using generally in imaging purposes while reactor produced radionuclides have also therapeutic applications. With the advent of emission tomography, new vistas for probing biochemistry in vivo have been opened. The radio chemist faces an ever-increasing challenge of designing new tracers for diagnostic and therapeutic applications. Rapid, efficient and automated methods of radionuclide and precursor production, labeling of biomolecules, and quality control need to be developed. The purpose of this article is a short interface from Nuclear Medicine, Radiation Biology and Radiotherapy, Dosimetry and Medical Radiation Physics Applications of Nuclear Sciences.

  13. Noble gases in nuclear medicine

    International Nuclear Information System (INIS)

    Calderon, M.; Burdine, J.A.

    1973-01-01

    Radioactive noble gases have made a significant contribution to diagnostic nuclear medicine. In the area of regional assessment of pulmonary function, 133 Xe has had its greatest clinical impact. Following a breath of 133 Xe gas, pulmonary ventilation can be measured using a scintillation camera or other appropriate radiation detector. If 133 Xe dissolved in saline is injected intravenously, both pulmonary capillary perfusion and ventilation can be measured since 90 percent of the highly insoluble xenon escapes into the alveoli during the first passage through the lungs. Radionuclide pulmonary function tests provide the first qualitative means of assessing lung ventilation and blood flow on a regional basis, and have recently been extended to include quantification of various parameters of lung function by means of a small computer interfaced to the scintillation camera. 133 Xe is also used in the measurement of organ blood flow following injection into a vessel leading into an organ such as the brain, heart kidneys, or muscles

  14. Current Status of The Korean Society of Nuclear Medicine

    International Nuclear Information System (INIS)

    Koh, Chang Soon

    1977-01-01

    As the application of nuclear medicine to clinics became generalized and it held an important position, the Korean Society of Nuclear Medicine was founded in 1961, and today it has become known as one of the oldest nuclear medicine societies not only to Asian nations but also to other advanced countries all over the world. Now it has 100 or so regular members composed of students of each medicine filed unlike other medical societies. Only nuclear medicine research workers are eligible for its membership. The Korean Society of Nuclear Medicine holds its regular general meeting and symposium twice per annom respectively in addition to occasional group gatherings and provincial lectures on nuclear medicine. With an eye to exchanging information on symposium, research and know-how, KSNM issued its initial magazine in 1967. Every year two editions are published. Year after year the contents of treatises are getting elevated with researches on each field including the early study on morphology-greatly improved both in quality and quantity. Of late, a minute and fixed quantity of various matters by dynamical research and radioimmunoassay of every kind has become visibly active. In particular, since KSNM, unlike other local societies, keeps close and frequent contact with the nuclear medicine researchers of world-wide fame, monographs by eminent scholars of the world are carried in its magazine now internationally and well received in foreign countries. Now the magazine has been improved to such an extent that foreign authors quote its contents. KSNM invited many a foreign scholar with a view to exchanging the knowledge of nuclear medicine. Sponsored by nuclear energy institute, the nuclear medicine symposium held in Seoul in October of 1966 was a success with Dr. Wagner participating, a great scholar of world wide fame: It was the first international symposium ever held in Korea, and the Korea Japan symposium held in Seoul 1971 was attended by all distinguished nuclear

  15. Role of nuclear medicine in imaging companion animals

    International Nuclear Information System (INIS)

    Currie, Geoffrey M.; Wheat, Janelle M.

    2005-01-01

    The role of equine nuclear medicine in Australia has been previously described in this journal and more recently, Lyall et al. provided a general overview of demographics of veterinary nuclear medicine departments in Australia. Lyall et al. discuss the main clinical applications of nuclear medicine scintigraphy in companion animals; dogs and cats. The aim of this article is to discuss in brief the applications of commonly performed nuclear medicine procedures in humans with respect to veterinary applications. More detailed discussion will also be offered for investigation of pathologies unique to veterinary nuclear medicine or which are more common in animals than humans. Companion animals are living longer today due to advances in both veterinary and human medicine. The problem is, like humans, longevity brings higher incidence of old age morbidity. As a pet owner, one might be initially motivated to extend life expectancy which is followed by the realisation that one also demands quality of life for pets. Early detection through advanced diagnostic tools, like nuclear medicine scintigraphy, allows greater efficacy in veterinary disease. There are limited veterinary nuclear medicine facilities in Australia due to cost and demand. Not surprisingly then, the growth of veterinary nuclear medicine in Australia, and overseas, has been integrally coupled to evaluation of race horses. While these facilities are generally specifically designed for race horses, racing greyhounds, lame family horses and companion animals are being investigated more frequently. In the USA, the American College of Veterinary Radiology (ACVC) is very active clinically and in research. The ACVC journal, Journal of Veterinary Radiology and Ultrasound, is published quarterly and includes a Nuclear Medicine section. Within the ACVR is the Society of Veterinary Nuclear Medicine. Proliferation of veterinary nuclear medicine centres in the USA has been associated with insurance and lifestyle changes

  16. Algorithms of image processing in nuclear medicine

    International Nuclear Information System (INIS)

    Oliveira, V.A.

    1990-01-01

    The problem of image restoration from noisy measurements as encountered in Nuclear Medicine is considered. A new approach for treating the measurements wherein they are represented by a spatial noncausal interaction model prior to maximum entropy restoration is given. This model describes the statistical dependence among the image values and their neighbourhood. The particular application of the algorithms presented here relates to gamma ray imaging systems, and is aimed at improving the resolution-noise suppression product. Results for actual gamma camera data are presented and compared with more conventional techniques. (author)

  17. 1. A brief history of nuclear medicine

    International Nuclear Information System (INIS)

    Dienstbier, Z.

    1989-01-01

    The milestones of history of nuclear medicine are dealt with. A brief account is given of the history of nuclear medicine abroad, and a more in-depth treatment is devoted to Czechoslovakia, where the beginning of this branch of science dates to 1951. (Z.S.)

  18. Quality assurance of nuclear medicine instruments

    International Nuclear Information System (INIS)

    Soni, P.S.

    1998-01-01

    Quality assurance in nuclear medicine refers collectively to all aspects of a nuclear medicine programme that may contribute directly or indirectly to the quality of the results obtained. For examples, patients scheduling; preparation and dispensing of radiopharmaceutical; the protection of patients, staff and the general public against radiation hazards and accidents caused by faulty instruments; methodology, data interpretation and record keeping

  19. Guidelines for patient information in nuclear medicine

    International Nuclear Information System (INIS)

    Anon.

    2010-01-01

    This guide for patients information in nuclear medicine is organised in the following manner: what is a medical examination in nuclear medicine, the preparation and the duration of the examination, the possible risks and the radiation doses, pregnancy, delayed menstruation and nursing and what to do after the examination. (N.C.)

  20. Single-purpose nuclear medicine instruments

    International Nuclear Information System (INIS)

    Boucek, J.

    Nuclear medicine requires the most up-to-date specialized technical facilities. The paper underlines the factor of reliability in purpose-designed equipment used for basic examinations. The possibility is also discussed of the automation of standard nuclear medicine instruments

  1. Computers for use in nuclear medicine

    International Nuclear Information System (INIS)

    Surova, H.

    1991-01-01

    Brief information is presented on computers for nuclear medicine that are currently available on the market. The treatment is based on print material by various manufacturers and commercial organizations and on the publication ''Nuclear Medicine Computers - A Personal Comparison Chart'' of May 1991, issued by the Reilly Publishing Company. (Z.S.)

  2. Links between nuclear medicine and radiopharmacy

    International Nuclear Information System (INIS)

    Pelegrin, M.; Francois-Joubert, A.; Chassel, M.L.; Desruet, M.D.; Bolot, C.; Lao, S.

    2010-01-01

    Radiopharmaceuticals are nowadays under the responsibility of the radio-pharmacist because of their medicinal product status. Radiopharmacy belongs to the hospital pharmacy department, nevertheless, interactions with nuclear medicine department are important: rooms are included or located near nuclear medicine departments in order to respect radiation protection rules, more over staff, a part of the material and some activities are shared between the two departments. Consequently, it seems essential to formalize links between the radiopharmacy and the nuclear medicine department, setting the goals to avoid conflicts and to ensure patients' security. Modalities chosen for this formalization will depend on the establishment's organization. (authors)

  3. Gamma Camera with Image Amplifier: Application in Nuclear Medicine; Camera Gamma a Amplificateur d'Image: Application en Medecine Nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Kellershohn, C.; Vernejoul, P. de; Desgrez, A. [CEA, Service Hospitalier Frederic Joliot, Orsay (France); Lequais, J.; Roux, G.; Lansiart, A. [CEA, Centre d' Etudes Nucleaires de Saclay, Gif-Sur-Yvette (France)

    1969-05-15

    The camera described has an optical system consisting of a lead grid collimator with 649 cylindrical channels 130 mm long and 5.5 mm in diameter; a detector consisting of a mosaic of 700 NaI(Tl) crystals with an effective diameter of 5.5 mm, length 20 mm, and a distance of 7.5 mm between the axes; and a light amplification device consisting of an initial image amplifier (No. 9463 of the French Thomson-Houston Company), the photocathode of which is in optical contact with the detector and is itself optically coupled to a second, high-gain light amplifier (P 829A, from English Electric Valve). In accordance with a principle first laid down during the preceding Conference on Medical Isotope Scanning organized by the International Atomic Energy Agency, this second amplifier may also be used as an electronic shutter operated by a photomultiplier which selects the light originating in the radio active source under examination. This device very effectively suppresses the background from the first amplifier tube. With reference to applications, the camera is used for two types of operation: firstly for the activation of the electronic shutter device, the rate of whose opening and shutting may reach 10 kHz; the background is almost entirely eliminated and it is possible with trace doses of conventional radionuclides to obtain images of such organs as the thyroid, liver, kidney, etc., in very short exposure times by comparison with customary scanning; secondly, by utilizing radionuclides of very short half-life with very high activities (of the order of several mCi), it is no longer necessary to effect suppression of the background whose repetition frequency is limited to 10 kHz. One can thus obtain ultrashort exposure times, e.g., about 1/20th of a second for an amount of 10 mCi of {sup 99m}Tc; such exposure times make cinematography possible. Various examples are supplied of applications making use of {sup 99m}Tc, {sup 137m}Ba and {sup 133}Xe in the field of vascular and

  4. Course on internal dosimetry in nuclear medicine

    International Nuclear Information System (INIS)

    2004-01-01

    This documentation was distributed to the participants in the Course of Internal Dosimetry in Nuclear Medicine organised by the Nuclear Regulatory Authority (ARN) of Argentina and held in Buenos Aires, Argentina, August 9-13, 2004. The course was intended for people from IAEA Member States in the Latin American and Caribbean region, and for professionals and workers in medicine, related with the radiation protection. Spanish and English were the languages of the course. The following subjects were covered: radioprotection of the patient in nuclear medicine; injuries by ionizing radiations; MIRD methodology; radiation dose assessment in nuclear medicine; small scale and microdosimetry; bone and marrow dose modelling; medical internal dose calculations; SPECT and image reconstruction; principles of the gamma camera; scattering and attenuation correction in SPECT; tomography in nuclear medicine

  5. Positron in nuclear medicine imaging

    International Nuclear Information System (INIS)

    Basu, S.

    2012-01-01

    The last two decades have witnessed a rapid expansion of clinical indications of positron emission tomography (PET) based imaging in assessing a wide range of disorders influencing their clinical management. This is primarily based upon a large dataset of evidence that has been generated over the years. The impact has been most remarkable in the field of cancer, where it takes a pivotal role in the decision making (at initial diagnosis, early response assessment and following completion of therapeutic intervention) of a number of important malignancies. The concept of PET based personalized cancer medicine is an evolving and attractive proposition that has gained significant momentum in recent years. The non-oncological applications of PET and PET/CT are in (A) Cardiovascular Diseases (e.g. Myocardial Viability, Flow reserve with PET Perfusion Imaging and atherosclerosis imaging); (B) Neuropsychiatric disorders (e.g. Dementia, Epileptic Focus detection, Parkinson's Disease, Hyperkinetic Movement Disorders and Psychiatric diseases); (C) Infection and Inflammatory Disorders (e.g. Pyrexia of Unknown origin, complicated Diabetic Foot, Periprosthetic Infection, Tuberculosis, Sarcoidosis, Vasculitic disorders etc). Apart from these, there are certain novel clinical applications where it is undergoing critical evaluation in various large and small scale studies across several centres across the world. The modality represents a classical example of a successful translational research of recent times with a revolutionary and far-reaching impact in the field of medicine. (author)

  6. Nuclear medicine resources in the internet

    International Nuclear Information System (INIS)

    Obaldo, J.M.

    1996-01-01

    The internet is a global collection of networked computers linked by a set of protocols which allows the otherwise disperate computer systems to communicate with each other. In contrast to text-only data available previously, the World Wide Web allows multimedia content to be available on the internet. Graphics can now likewise be used as links. The development of World Wide Web client software such as Mosaic, or the currently more popular Netscape Navigator, makes linking from one document to another (colloquially referred to as 'surfing the Net') fast and simple. While these software are commonly called Web browsers their function extends to the other internet services such as e-mail, file transfer protocol, remote login, Gopher and WAIS. A prototype application being developed as a case-based teaching file which could include clinical data and case discussion, aside of course from the nuclear medicine and related images. Contributions from various institutions can be made available on their own servers and linked together through hypertext. Examples of these are websites of the Mallinckrodt Institute of Radiology and the Joint Program in Nuclear Medicine of the Harvard Medical School. The university of Iowa also has its Virtual Hospital, a collection of clinical cases with radiologic images. Most major universities and medical centers have websites where information on on-going research, facilities and personnel are made available. Links to various special interest discussion groups (e.g. those developing the common image file format) are also accessible and the documents often contain further links to related fields in nuclear technology. The very nature of the hypertext transfer protocol of the World Wide Web makes it a relatively simple matter for a developer of a teaching system to include links to necessary resources. It is envisioned that an internet-based teaching module will be incorporated in some nuclear medicine training programs in the United States

  7. Computers in nuclear medicine - current trends and future directions

    International Nuclear Information System (INIS)

    Anon.

    1994-01-01

    Previously, a decision to purchase computing equipment for nuclear medicine usually required evaluation of the 'local' needs. With the advent of Pacs and state of the art computer techniques for image acquisition and manipulation, purchase and subsequent application is to become much more complex. Some of the current trends and future possibilities which may influence the choice and operation of computers within and outside the nuclear medicine environment is discussed. (author)

  8. Magnetic resonance vs. computerized tomography, ultrasonic examinations and nuclear medicine

    International Nuclear Information System (INIS)

    Bruna, J.

    1985-01-01

    A symposium on magnetic resonance in nuclear medicine was held from 23rd to 27th January, 1985 in Munich and Garmisch-Partenkirchen. Discussed were suitable methods, the use of contrast media, the evaluation of results, the application of nuclear magnetic resonance in examining various body organs, and the latest apparatus. NMR achievements in medicine were compared to those by other diagnostic methods. (M.D.)

  9. Introduction to hardware for nuclear medicine data systems

    International Nuclear Information System (INIS)

    Erickson, J.J.

    1976-01-01

    Hardware included in a computer-based data system for nuclear medicine imaging studies is discussed. The report is written for the newcomer to computer collection and analysis. Emphasis is placed on the effect of the various portions of the system on the final application in the nuclear medicine clinic. While an attempt is made to familiarize the user with some of the terms he will encounter, no attempt is made to make him a computer expert. 1 figure, 2 tables

  10. The research progress of nuclear medicine on cardiovascular molecular imaging

    International Nuclear Information System (INIS)

    Yin Xiaohua; Zhang Yongxue

    2007-01-01

    Cardiovascular molecular imaging is a rapidly evolving discipline and its clinical application is promising. Nuclear medicine is playing a leading role in this field with its special superiority of noninvasive, quantifiability, high sensitivity and specificity. It provides broad opportunities for exploring the pathophysiologic process of cardiovascular diseases and monitoring its gene therapy in the molecular level. In this review, we mainly discuss some basic knowledge on cardiovascular molecular imaging, and then focus on the applied research prospect of nuclear medicine radionuclide imaging. (authors)

  11. Official Program and Abstracts of the 15. Meeting of the Latin-American Association of Biology and Nuclear Medicine Societies (ALASBIMN 97); Iberoamerican Congress of Nuclear Medicine

    International Nuclear Information System (INIS)

    1997-01-01

    This issue contains 117 abstracts of lectures and poster sessions of the 15th Meeting of the Latin-American Association of Biology and Nuclear Medicine Societies (ALASBIMN 97) and Iberoamerican Congress of Nuclear Medicine, held in Lima, Peru, from 26 to 30 October 1997. The key subjects addressed are nuclear medicine and diagnostic techniques on brain, liver, lungs, heart, osteo-articular, cardiology, oncology, endocrinology, radiopharmaceuticals, medical physics, SPECT and their applications in diagnostic medicine. (APC)

  12. Nuclear medicine - the condition and prospects

    International Nuclear Information System (INIS)

    Zaredinov, D.A.; Altaeva, B.M.

    2004-01-01

    Full text: The nuclear medicine has rather strongly determined the place in clinical and diagnostic practice. Statistical researches show, that, even despite of the certain successes in treatment of many diseases, rather high death rate at cardiovascular, oncological and many other diseases. The urgency of clinical tasks connected with a state of health of the population puts before nuclear medicine a (task) on development and introduction of new methods of diagnostics and therapy. The nuclear medicine is characterized by some number of diagnostic and therapeutic methods which application frequently does not have other alternative. The methods of visualization used in nuclear medicine, are full informative, exact and have ability to reveal structurally functional changes of bodies and fabrics practically at a cellular level. To present time diagnostic radiopharmacy (Ph) wed practically in all clinical areas of medicine. In world practice steady growth of increase of manufacture as diagnostic and radiotherapeutic RP was planned. The even greater (reduction) of potential risk one and of conditions by which development of nuclear medicine in the near future is defined is at realization of the procedures connected to application of radioactive preparations and reduction of beam loadings on the patient. An important point in the clinic-diagnostic field is replacement the RP on short-lived and ultra short-lived. Among examples of such transition it is necessary to name replacement 131 I in diagnostic application on 123 I, and also active introduction PET. It is possible to call essentially new direction of development of technologies of the directed transport the open radioactive isotopes and RP to pathology changed bodies or organisms demanding realization of diagnostic procedures or selective beam therapy. However, despite of huge potential opportunities of the domestic nuclear industry, even such old method as the radiotherapy I-131 - is used by iodine in our country

  13. Experience with Nuclear Medicine Information System

    Directory of Open Access Journals (Sweden)

    Bilge Volkan-Salanci

    2012-12-01

    Full Text Available Objective: Radiology information system (RIS is basically evolved for the need of radiologists and ignores the vital steps needed for a proper work flow of Nuclear Medicine Department. Moreover, CT/MRI oriented classical PACS systems are far from satisfying Nuclear Physicians like storing dynamic data for reprocessing and quantitative analysis of colored images. Our purpose was to develop a workflow based Nuclear Medicine Information System (NMIS that fulfills the needs of Nuclear Medicine Department and its integration to hospital PACS system. Material and Methods: Workflow in NMIS uses HL7 (health level seven and steps include, patient scheduling and retrieving information from HIS (hospital information system, radiopharmacy, acquisition, digital reporting and approval of the reports using Nuclear Medicine specific diagnostic codes. Images and dynamic data from cameras of are sent to and retrieved from PACS system (Corttex© for reprocessing and quantitative analysis. Results: NMIS has additional functions to the RIS such as radiopharmaceutical management program which includes stock recording of both radioactive and non-radioactive substances, calculation of the radiopharmaceutical dose for individual patient according to body weight and maximum permissible activity, and calculation of radioactivity left per unit volume for each radionuclide according their half lives. Patient scheduling and gamma camera patient work list settings were arranged according to specific Nuclear Medicine procedures. Nuclear Medicine images and reports can be retrieved and viewed from HIS. Conclusion: NMIS provides functionality to standard RIS and PACS system according to the needs of Nuclear Medicine. (MIRT 2012;21:97-102

  14. Specific features of occupational medicine in nuclear research and industry

    International Nuclear Information System (INIS)

    Giraud, J.M.; Quesne, B.

    2003-01-01

    Measures to prevent the exposure of personnel to ionising radiation were taken as soon as the first nuclear laboratories were set up. This branch of occupational preventive medicine has since kept pace with advances in research and in the industrial applications of nuclear energy. (authors)

  15. Diagnostic nuclear medicine. 2. rev. ed.

    International Nuclear Information System (INIS)

    Schiepers, C.

    2006-01-01

    The field of nuclear medicine is undergoing rapid expansion, and is evolving into diagnostic molecular imaging. During recent years, dual-modality imaging with PET/CT has gained acceptance and this is currently the fastest-growing technique for oncological imaging applications. The glucose analogue FDG has held its place in diagnostic oncology, assessment of myocardial viability and diagnosis of neuro-degenerative disorders. Peptides have become even more important as imaging agents. The accuracy of hepatobiliary scintigraphy has been enhanced by cholecystokinin. The use of ACE inhibitors in the evaluation of renovascular hypertension has become the standard in renography. New instrumentation has led to faster scanners, and computer development to better image processing software. Automatic processing is more common, and standardization of protocols can be accomplished easily. The field of gene imaging has progressed, although routine clinical applications are not yet available. The present text, supplemented with many detailed and informative illustrations, represents an adjunct to the standard knowledge of diagnostic nuclear medicine and provides both the student and the professional with an overview of developments during the past decade. (orig.)

  16. Maintenance of nuclear medicine instruments

    Energy Technology Data Exchange (ETDEWEB)

    Ambro, P

    1993-12-31

    Maintenance of instruments is generally of two kinds: (a) corrective maintenance, on a non-scheduled basis, to restore equipment to a functional status by repairs; (b) preventive maintenance, to keep equipment in a specified functional condition by providing systematic inspection, quality control, detection and correction of early malfunctions. Most of the instruments used in nuclear medicine are rather complex systems built from mechanical, electrical and electronic parts. Any one of these components is liable to fail at some time or other. Repair could be done only by a specialist who is able to evaluate the condition of the various parts ranging from cables to connectors, from scintillators to photomultipliers, from microprocessors to microswitches. The knowledge of the intricacies of the various electronic components required for their repairs is quite wide and varied. The electronics industry turns out more and more multi-purpose chips which can carry out the functions of many parts used in the instruments of the earlier generation. This provides protection against unauthorized copying of the circuits but it serves another purpose as well of inhibiting repairs by non-factory personnel. These trends of the instrument design should be taken into consideration when a policy has to be developed for the repairs of the hospital based equipment 1 fig., 1 tab

  17. Maintenance of nuclear medicine instruments

    International Nuclear Information System (INIS)

    Ambro, P.

    1992-01-01

    Maintenance of instruments is generally of two kinds: (a) corrective maintenance, on a non-scheduled basis, to restore equipment to a functional status by repairs; (b) preventive maintenance, to keep equipment in a specified functional condition by providing systematic inspection, quality control, detection and correction of early malfunctions. Most of the instruments used in nuclear medicine are rather complex systems built from mechanical, electrical and electronic parts. Any one of these components is liable to fail at some time or other. Repair could be done only by a specialist who is able to evaluate the condition of the various parts ranging from cables to connectors, from scintillators to photomultipliers, from microprocessors to microswitches. The knowledge of the intricacies of the various electronic components required for their repairs is quite wide and varied. The electronics industry turns out more and more multi-purpose chips which can carry out the functions of many parts used in the instruments of the earlier generation. This provides protection against unauthorized copying of the circuits but it serves another purpose as well of inhibiting repairs by non-factory personnel. These trends of the instrument design should be taken into consideration when a policy has to be developed for the repairs of the hospital based equipment

  18. Nuclear medicine: the Philippine Heart Center experience

    International Nuclear Information System (INIS)

    Cancino, E.L.

    1994-01-01

    The following is a report of a three (3) months on-the-job training in Nuclear Medicine at the Nuclear Medicine Department of the Philippine Heart Center. The hospital has current generation nuclear medicine instruments with data processor and is capable of a full range of in vivo and in vitro procedures. Gamma camera is the principal instrument for imaging in nuclear medicine used in the Philippine Heart Center. Thyroid scanning procedure is being performed with these instruments. Also the cardiovascular procedures, the pulmonary, skeletal, renal and hepatobiliary procedures were being performed with the use of gamma camera. Special emphasis is on nuclear cardiology since the PHC attends primarily to cardiovascular patients. (auth.)

  19. Quality control of nuclear medicine instruments 1991

    International Nuclear Information System (INIS)

    1991-05-01

    This document gives detailed guidance on the quality control of various instruments used in nuclear medicine. A first preliminary document was drawn up in 1979. A revised and extended version, incorporating recommended procedures, test schedules and protocols was prepared in 1982. The first edition of ''Quality Control of Nuclear Medicine Instruments'', IAEA-TECDOC-317, was printed in late 1984. Recent advances in the field of nuclear medicine imaging made it necessary to add a chapter on Camera-Computer Systems and another on SPECT Systems. Figs and tabs

  20. Quality control of nuclear medicine instruments, 1991

    International Nuclear Information System (INIS)

    1996-12-01

    This document gives detailed guidance on the quality control of various instruments used in nuclear medicine. A first preliminary document was drawn up in 1979. A revised and extended version, incorporating recommended procedures, test schedules and protocols was prepared in 1982. The first edition of 'Quality Control of Nuclear Medicine Instruments', IAEA-TECDOC-317, was printed in late 1984. Recent advances in the field of nuclear medicine imaging made it necessary to add a chapter on Camera-Computer Systems and another on SPECT Systems

  1. Protection of the patient in nuclear medicine

    International Nuclear Information System (INIS)

    1987-01-01

    In ICRP Publication 52, the 'Protection of the Patient in Nuclear Medicine', is concerned with exposures of patients resulting from the administration of radiopharmaceuticals for diagnostic, therapeutic and research purposes. The report includes guidelines for nuclear medicine physicians, radiologists, medical physicists and technologists on the factors that influence absorbed doses to patients from different types of nuclear medicine examinations. Other topics in the report include education and training, estimates of absorbed dose, design of facilities, instrumentation, quality assurance and control and preparation, quality assurance and control of radiopharmaceuticals. (U.K.)

  2. Physics and radiobiology of nuclear medicine

    CERN Document Server

    Saha, Gopal B

    2010-01-01

    From a distinguished author comes this new edition for technologists, practitioners, residents, and students in radiology and nuclear medicine. Encompassing major topics in nuclear medicine from the basic physics of radioactive decay to instrumentation and radiobiology, it is an ideal review for Board and Registry examinations. The material is well organized and written with clarity. The book is supplemented with tables and illustrations throughout. It provides a quick reference book that is concise but comprehensive, and offers a complete discussion of topics for the nuclear medicine and radi

  3. Nuclear medicine research: an evaluation of the ERDA program

    International Nuclear Information System (INIS)

    1976-08-01

    Legislation which established the Energy Research and Development Administration (ERDA) January 19, 1975, stipulated that this new agency should be responsible for all activities previously assigned to the Atomic Energy Commission (AEC) and not specifically assigned to other agencies. Such activities included the nuclear medicine research program of the AEC Division of Biomedical and Environmental Research (DBER). To determine whether continuation of this program under the broader ERDA mission of energy-related research was in fact appropriate, a special task force was appointed in January 1975 by Dr. James L. Liverman, the director of DBER. This task force, comprised of established scientists knowledgeable about issues related to nuclear medicine either currently or in the past, was charged specifically to assess the historical impact of the AEC/ERDA nuclear medicine program on the development of nuclear medicine, the current status of this program, and its future role within the structure of ERDA. The specific recommendations, in brief form, are as follows: the federal government should continue to support the medical application of nuclear technology; ERDA should retain primary responsibility for support and management of federal nuclear medicine research programs; and management and emphasis of the ERDA nuclear medicine program require modification in certain areas, which are set forth

  4. Advanced Accelerator Applications in Medicine

    International Nuclear Information System (INIS)

    Rimjiaem, Sakhorn

    2015-01-01

    besides the original purpose on development of particle acceleratora as research tools in nuclear and high-energy physics, there are large variety of accelerators used in various fileds from fundamental research to industrial usesand applications chemistry, biology and medicine. Pratical accelators used in various field of medical applications since serveral decades. Even through, a large fraction of applications is emphasized on cancer therappy, the number of accelerators used in midicine for other diagnostics and treatments has increased steady over the years. Several types of accelerated particles are used including electron, proton, neutron and ions. Presently, relativistic electron beams and radiation from linear accelerators (linas) are widely used. A combination of positron emission tomography (PRT) and radiotherapy is an example of excellent invention early detection and treat of cancer tumors. The most developments for proton and heavy ion therapy as well as a modern boron neutron capture therapy (BNCT) are also great incoming effective systems. This talk will focus on developments of the accelrator systems as well as overview on biophysical properties and medical aspects of the diacnostics and treatments.

  5. Integrating cardiology for nuclear medicine physicians. A guide to nuclear medicine physicians

    International Nuclear Information System (INIS)

    Movahed, Assad; Gnanasegaran, Gopinath; Buscombe, John R.; Hall, Margaret

    2009-01-01

    Nuclear cardiology is no longer a medical discipline residing solely in nuclear medicine. This is the first book to recognize this fact by integrating in-depth information from both the clinical cardiology and nuclear cardiology literature, and acknowledging cardiovascular medicine as the fundamental knowledge base needed for the practice of nuclear cardiology. The book is designed to increase the practitioner's knowledge of cardiovascular medicine, thereby enhancing the quality of interpretations through improved accuracy and clinical relevance.The text is divided into four sections covering all major topics in cardiology and nuclear cardiology: -Basic Sciences and Cardiovascular Diseases; -Conventional Diagnostic Modalities; -Nuclear Cardiology; -Management of Cardiovascular Diseases. (orig.)

  6. Nuclear Medicine at Charles Sturt University

    International Nuclear Information System (INIS)

    Swan, H.; Sinclair, P.; Scollard, D.

    1998-01-01

    Full text: A distance educational programme for upgrading of Certificate, Associate Diploma and Diploma to a Bachelor of Applied Science degree commenced in second semester of 1997 with approximately 15 Australian students and 15 Canadian students. The first graduation will occur in 1998. Formal links with the Michener Institute in Toronto have allowed Canadian students access to study resources during the course. All students entering the course are accredited or registered with their respective professional societies. The short conversion programme for those with three year diplomas includes Nuclear Medicine Physics and Instrumentation, Imaging Pathology, Clinical Neuroscience and Research Method subjects. An inaugural undergraduate degree programme in Nuclear Medicine Technology commences in first semester of 1998 on the Riverina Campus at Wagga Wagga. An intake of 15 students is anticipated. This small group of rural based students will have the benefits of international expertise. The programme has a strong clinical practice component including time on campus to supplement the practicum in departments. Physiology studies continue through to third year to complement the professional subjects. Active participation is solicited from those departments involved with aspects of the practicum well before students are placed. A fully functional teaching laboratory has been constructed containing a well equipped radiopharmacy, gamma camera room and computer laboratory using modern applications software to provide the students with a solid background in their chosen field

  7. Nuclear medicine in the nephrourinary tract

    International Nuclear Information System (INIS)

    Jofre M, M.Josefina; Sierralta C, Paulina

    2002-01-01

    Nuclear medicine images play an important role in the evaluation of urinary tract pathologies. Radionuclide imaging studies (DMSA scan, DTPA/MAG3 renography, radionuclide cistography) are reviewed, analyzing their indications (au)

  8. Internal dosimetry in nuclear medicine procedures

    International Nuclear Information System (INIS)

    Carrera Magarino, F.; Salgado Garcia, C.; Ruiz Manzano, P.; Rivas Ballarin, M. A.; Jimenez Hefernan, A.; Sanchez Segovia, J.

    2011-01-01

    The Department of Radio Physics and Radiation Protection, University Hospital Lozano Blesa Zaragoza presented a calculus textbook to estimate patient doses in diagnostic nuclear medicine. In this paper present an updated referred Book of calculation.

  9. Radiation exposure of workers in nuclear medicine

    International Nuclear Information System (INIS)

    Bujnova, A.

    2008-01-01

    Nuclear medicine is an interdisciplinary department that deals with diagnosis and therapy using open sources. Therefore workers in nuclear medicine are in daily contact with ionizing radiation and thus it is essential to monitor a radiation load. Each work must therefore carry out monitoring of workers. It monitors compliance with the radiation limits set by law, allows an early detection of deviations from normal operation and to demonstrate whether the radiation protection at the workplace is optimized. This work describes the principles of monitoring of workers in nuclear medicine and monitoring methods for personal dosimetry. In the next section the author specifically deals with personal dosimetry at the Department of Nuclear Medicine St. Elizabeth Cancer Institute, Bratislava (KNM-Ba-OUSA). The main part of the work is to evaluate the results of a one-year monitoring of radiation workers KNM-Ba-OUSA. (author)

  10. Aplications of Nuclear Medicine in endocrinology

    International Nuclear Information System (INIS)

    Jales, R.L.C.

    1981-01-01

    A scanning of thyroid has been undertaked by using radioactive isotopes. Clinical procedures performed in the nuclear medicine field were cited along with its principles and interpretation. (Author) [pt

  11. Hand Dose in Nuclear Medicine Staff Members

    International Nuclear Information System (INIS)

    Taha, T.M.; Shahein, A.Y.; Hassan, R.

    2009-01-01

    Measurement of the hand dose during preparation and injection of radiopharmaceuticals is useful in the assessment of the extremity doses received by nuclear medicine personnel. Hand radiation doses to the occupational workers that handling 99m Tc-labeled compounds, 131 I for diagnostic in nuclear medicine were measured by thermoluminescence dosimetry. A convenient method is to use a TLD ring dosimeter for measuring doses of the diagnostic units of different nuclear medicine facilities . Their doses were reported in millisieverts that accumulated in 4 weeks. The radiation doses to the hands of nuclear medicine staff at the hospitals under study were measured. The maximum expected annual dose to the extremities appeared to be less than the annual limit (500 mSv/y) because all of these workers are on rotation and do not constantly handle radioactivity throughout the year

  12. Systematic thinks of nuclear medicine diagnosis

    International Nuclear Information System (INIS)

    Wang Jing

    2002-01-01

    For proper diagnosis using nuclear medicine techniques, an integrated man-machine system should be the starting point; the best choice should be the essential purpose and modeling is the necessary method

  13. Radiation hazards in the nuclear medicine

    International Nuclear Information System (INIS)

    Roo, M.J.K. de

    1981-01-01

    After a survey of the actual situation of nuclear medicine in Belgium, the evolution of nuclear medicine is studied with regard to quantitative aspects (tracerquantities, number of radioisotopic explorations, number of certified doctors) and qualitative aspects (use of short living isotopes emitting low energy radiation, introduction of in vitro tests). Taking these data into consideration, the exposure of nuclear medicine staff by external or internal radiation is evaluated. From this study it appears that the radiation exposure of the personnel of nuclear medicine departments remains low if proper manipulation methods and simple protective devices are used and if there is an efficient collaboration with an active health physics department or radiation control organism. (author)

  14. Case assessments for nuclear medicine registrars

    International Nuclear Information System (INIS)

    Farlow, D.

    1994-01-01

    Westmead Hospital set some of the recent nuclear medicine cases for registrar training. These case assessments have been completed by the registrars and he thought it might be interesting for the general nuclear medicine community to attempt the cases themselves and compare their answers with the model reports and patient follow-ups. Edited versions of two cases and model answers are presented. 35 refs

  15. Molecular methods in nuclear medicine therapy

    International Nuclear Information System (INIS)

    Lee, Kyung Han

    2001-01-01

    Nuclear medicine has traditionally contributed to molecular oncology by allowing noninvasive monitoring of tumor metabolism, growth and genetic changes, thereby providing a basis for appropriate biology-based treatment planning. However, NM techniques are now being applied as an active therapeutic tool in novel molecular approaches for cancer treatment. Such areas include research on cancer therapy with radiolabeled ligands or oligonucleotides, and utilization of synergism between NM radiotherapy and gene transfer techniques. Here we will focus on novel aspects of nuclear medicine therapy

  16. Applications of electrochemistry in medicine

    CERN Document Server

    Schlesinger, Mordechay

    2013-01-01

    Medical Applications of Electrochemistry, a volume of the series Modern Aspects of Electrochemistry, illustrates the interdisciplinary nature of modern science by indicating the many current issues in medicine that are susceptible to solution by electrochemical methods. This book also suggests how personalized medicine can develop.

  17. Medical Imaging Informatics in Nuclear Medicine

    NARCIS (Netherlands)

    van Ooijen, Peter; Glaudemans, Andor W.J.M.; Medema, Jitze; van Zanten, Annie K.; Dierckx, Rudi A.J.O.; Ahaus, C.T.B. (Kees)

    2016-01-01

    Medical imaging informatics is gaining importance in medicine both in clinical practice and in scientific research. Besides radiology, nuclear medicine is also a major stakeholder in medical imaging informatics because of the variety of available imaging modalities and the imaging-oriented operation

  18. A DICOM based PACS for nuclear medicine

    International Nuclear Information System (INIS)

    Lassmann, M.; Reiners, C.

    2002-01-01

    The installation of a radiology information system (RIS) connected to a hospital information system (HIS) and a picture archiving and communications system (PACS) seems mandatory for a nuclear medicine department in order to guarantee a high patient throughput. With these systems a fast transmission of reports, images to the in- and out-patients' wards and private practitioners is realized. Therefore, since April 2000, at the department of nuclear medicine of the university of Wuerzburg a completely DICOM based PACS has been implemented in addition to the RIS. With this system a DICOM based workflow is realized throughout the department of nuclear medicine for reporting and archiving. The PACS is connected to six gamma-cameras, a PET scanner, a bone densitometry system and an ultrasound device. The volume of image data archived per month is 4 GByte. Patient demographics are provided to the modalities via DICOM-Worklist. With these PACS components a department specific archive purely based on DICOM can be realized. During the installation process problems occurred mainly because of the complex DICOM standard for nuclear medicine. Related to that is the problem that most of the software implementations still contain bugs or are not adapted to the needs of a nuclear medicine department (particularly for PET). A communication software for the distribution of nuclear medicine reports and images based on techniques used for the worldwide web is currently tested. (orig.) [de

  19. Special monitoring in nuclear medicine; Monitoreo especial en medicina nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Beltran, C.C.; Puerta, J.A.; Morales, J. [Asociacion Colombiana de Proteccion Radiologica (Colombia)]. e-mail: ccbeltra@gmail.com

    2006-07-01

    Colombia counts with around 56 centers of Nuclear Medicine, 70 Nuclear Doctors and more of 100 Technologists in this area. The radioisotopes more used are the {sup 131} I and the {sup 99m} Tc. The radiological surveillance singular in the country is carried out for external dosimetry, being the surveillance by incorporation of radioactive materials very sporadic in our media. Given the necessity to implement monitoring programs in the incorporation of radionuclides of the occupationally exposed personnel, in the routine practice them routine of Nuclear Medicine, it was implemented a pilot program of Special Monitoring with two centers of importance in the city of Medellin. This program it was carried out with the purpose of educating, to stimulate and to establish a program of reference monitoring with base in the National Program of Monitoring in the radionuclides Incorporation that serves like base for its application at level of all the services of Nuclear Medicine in the country. This monitoring type was carried out with the purpose of obtaining information on the work routine in these centers, form of manipulation and dosage of the radionuclides, as well as the administration to the patient. The application of the program was carried out to define the frequency of Monitoring and analysis technique for the implementation of a program of routine monitoring, following the recommendations of the International Commission of Radiological Protection. For their application methods of activity evaluation were used in urine and in 7 workers thyroid, of those which only two deserve an analysis because they presented important activities. The measures were carried out during one month, every day by means in urine samples and to the most critic case is practiced two thyroid measures, one in the middle of the period and another when concluding the monitoring. To the other guy is practiced an activity count in thyroid when concluding the monitoring period. The obtained

  20. In vivo diagnostic nuclear medicine. Pediatric experience

    International Nuclear Information System (INIS)

    Goetz, W.A.; Hendee, W.R.; Gilday, D.L.

    1983-01-01

    The use of radiopharmaceuticals for diagnostic tests in children is increasing and interest in these is evidenced by the addition of scientific sessions devoted to pediatric medicine at annual meetings of The Society of Nuclear Medicine and by the increase in the literature on pediatric dosimetry. Data presented in this paper describe the actual pediatric nuclear medicine experience from 26 nationally representative U.S. hospitals and provide an overview of the pediatric procedures being performed the types of radiopharmaceuticals being used, and the activity levels being administered

  1. VIIth international symposium on nuclear medicine

    International Nuclear Information System (INIS)

    1983-01-01

    The conference proceedings contain abstracts of 100 presented papers, mainly dealing with radioimmunoassays, radiopharmaceuticals, scintiscanning, computer tomography, radionuclide lymphography, ventriculography, angiography, nuclear cardiology, liquid scintillator techniques, radioisotope generators, radiospirometry and various uses of labelled compounds and tracer techniques in nuclear medicine. (M.D.)

  2. Information for nuclear medicine researchers and practitioners

    International Nuclear Information System (INIS)

    Bartlett, W.

    1987-01-01

    The Australian Nuclear Science and Technology Organisation (ANSTO) has a major research program in nuclear medicine; this article describes the information support given to the program by the Lucas Heights Research Laboratories (LHRL) Library. The INIS database is a prime indicator of the information held at LHRL Library, however, other databases also cover nuclear medicine. As part of the Australian library system the ANSTO Library's resources are accessed by subscription. The ANSTO Library staff can also search INIS for a fee for external enquiries but the other databases can presently only be searched for LHRL staff and affiliates. Even so, most major library and information services can provide access to these databases

  3. Current trends in nuclear medicine in Pakistan

    International Nuclear Information System (INIS)

    Kamal, S.; Ahmed, S.

    1990-01-01

    This volume is a compilation of dissertations on research projects submitted by the fellows of M. Sc. (Nuclear Medicine) who undertook a two-year intensive course initiated in 1989 by the Centre for Nuclear Studies, PINSTECH, Islamabad. The project covered major aspects of nuclear medicine including the cardiovascular, endocrine, haematopoietic, hepatobiliary, immune and skeletal systems. The results obtained proved interesting and of significant clinical relevance. Majority of essays addressed some new aspects of the problems and the resultants information should prove interesting for both local and foreign enthusiasts. This book proves a reflection of the high quality of work done by the faculty and the fellows. (orig./A.B.)

  4. Nuclear data applications in developing countries

    International Nuclear Information System (INIS)

    Mehta, M.K.; Schmidt, J.J.

    1985-01-01

    The peaceful applications of nuclear science and technology currently receive an increasing attention in many developing countries. More than 15 developing countries operate, construct or plan nuclear power reactors, 70 developing countries are using or planning to use nuclear techniques in medicine, agriculture, industry, and for other vital purposes. The generation, application and computer processing of nuclear data constitute important elements of the nuclear infrastructure needed for the successful implementation of nuclear science and technology. Developing countries become increasingly aware of this need, and, with the help and cooperation of the IAEA Nuclear Data Section, are steadily gaining in experience in this field. The paper illustrates this development in typical examples. (orig.)

  5. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... medicine exam, there are several things you can do to prepare. First, you may be asked not ... To help ensure current and accurate information, we do not permit copying but encourage linking to this ...

  6. Dynamic functional studies in nuclear medicine in developing countries

    International Nuclear Information System (INIS)

    1989-01-01

    The Proceedings document some of the trials and tribulations involved in setting up nuclear medicine facilities in general and specifically as regards nuclear medicine applications for the diagnosis of the diseases prevalent in the less developed countries. Most of the 51 papers deal with various clinical applications of dynamic functional studies. However, there was also a session on quality control of the equipment used, and a panel discussion critically looked at the problems and potential of dynamic studies in developing countries. This book will be of interest and use not only to those practising nuclear medicine in the developing countries, but it may also bring home to users in developed countries how ''more can be done with less''. Refs, figs and tabs

  7. Radiation protection problems by diagnostic procedures of pediatric nuclear medicine

    International Nuclear Information System (INIS)

    Kletter, K.

    1994-01-01

    Special dosimetry considerations are necessary in the application of radiopharmaceuticals in pediatric nuclear medicine. The influence of differences in irradiation geometry and biokinetic parameters on the radiation dose in children and adults is discussed. Assuming an equal activity concentration, both factors lead rather to a reduced radiation dose than an increased radiation burden in children compared to adults. However, the same radiation dose in children and adults may lead to a different detriment. This is explained by differences in life expectancy and radiation sensitivity for both groups. From special formulas an age dependent reduction factor can be calculated for the application of radiopharmaceuticals in pediatric nuclear medicine. Radiation exposure to hospital staff and parents from children, undergoing nuclear medicine diagnostic or therapeutic procedures, is low. (author)

  8. Abstracts of the European Association of Nuclear Medicine congress, 26-30 August 1995, Brussels, Belgium

    International Nuclear Information System (INIS)

    Anon.

    1995-01-01

    The issue contains 888 abstracts of lectures and poster sessions of the European Association of Nuclear Medicine Congress held in Brussels, Belgium, from August 26 to 30, 1995. The key subjects adressed are diagnostic nuclear medicine techniques, especially scintiscanning, SPET and PET and their applications in diagnostic medicine. There is an alphabetic index of author names. (vhe) [de

  9. Nuclear Technology applications

    International Nuclear Information System (INIS)

    Cibils Machado, W. E- mail: wrcibils@adinet.com.uy

    2002-01-01

    The present work tries on the applications of the nuclear technology in the life daily, such as agriculture and feeding, human health, industry, non destructive essays, isotopic hydrology, and the nuclear power stations for electricity production and radioisotopes production

  10. Aspects on caring in pediatric nuclear medicine

    International Nuclear Information System (INIS)

    Ljung, B.M.L.

    2002-01-01

    puncture or inability to lie still. It is concluded, that in the rapidly evolving field of pediatric nuclear medicine it is very important that aspects on patient care are applied, recognizing the possibilities provided by traditional methods and novel developments.Thus, patients and families can be informed prior to an examination via electronic media, topical anesthesia is available as well as short term sedation. Training of staff will furthermore secure application of modern care principles like 'Guided Imagery'

  11. Radiological Protection of Patients in Nuclear Medicine

    International Nuclear Information System (INIS)

    Rojo, A.M.

    2011-01-01

    Full text: This lecture aims at presenting the state of the art of radiological protection of patients in nuclear medicine focusing on three aspects of interest where to achieve improvement. The hierarchy of the justification principle of the radiation protection is one of them. There seems for a change to be presented in the paradigm of the radiological protection of patients. The role of the physician who prescribes the medical practice becomes more relevant, together with the nuclear medicine specialist who should be co-responsible for the application of this justification principle. Regarding the doses optimization and the implementation of Dose Reference Level the involvement extends far beyond the physician and radioprotection officer. It is clear that the Medical Physicist is to play a very relevant role in the coordination of actions, as the nuclear medicine technician is to execute them. Another aspect to consider is patient specific dosimetry. It should become a routine practice through calculation of the absorbed dose based on biodistribution data. It should be assessed for each individual patient, as it depends on a number of patient-specific parameters, such as gender, size and the amount of fatty tissue in the body, as well as the extent and nature of the disease. In most cases, dosimetry calculations are not carried out and patients are administered standard levels of activity. There may be situations with a lack of knowledge on internal dosimetry as in many centers either none or only one or two medical physics experts are available. It shows that a formal training for experts in internal dosimetry at national level is required. However up to now, there has been no satisfactory correlation between absorbed dose estimates and patient response. Moreover, the radiation protection for the patient is not assured, as the dose values given are often numbers without connection to radiobiological and/or hematological findings. Pending tasks related to

  12. Medicine and nuclear war - helpless

    International Nuclear Information System (INIS)

    1983-01-01

    At the end of the ''2nd Medical Congress for the Prevention of Nuclear War'' attention is again drawn to the fact that erroneous or intended use of nuclear weapons can kill hundreds of millions and make the earth unlivable. What physicians are refusing here is not to give whatever help they can or are obliged to. They are on strike against politicians and journalists who ascribe them an ability they do not possess. They refuse to be the objects of false praise pretending that they could be helpers or rescuers in the, unfortunately, not only possible but probable nuclear catastrophe. (orig./HSCH) [de

  13. Report on the second Congress of the Russian nuclear medicine society and on International conference Current problems of nuclear medicine and radiopharmaceuticals

    International Nuclear Information System (INIS)

    Lishmanov, Yu.B.; Chernov, V.I.

    2001-01-01

    Information on the work of Second Congress of Russian Nuclear Medicine Society and International Conference - Current problems of nuclear medicine and radiopharmaceuticals, - held in Obninsk in October, 2000, is adduced. Reports presented in the conference are dedicated to various aspects of application of radionuclide methods to cardiology, angiology, oncology, surgery, hematology, endocrinology, pediatrics and neurology. Problems in the development of radiopharmaceutical, training and skill advancement of experts, dosimetry and radiation safety in nuclear medicine were discussed. Congress considered the organizational problems in Russian nuclear medicine [ru

  14. Antivitamins for Medicinal Applications.

    Science.gov (United States)

    Zelder, Felix; Sonnay, Marjorie; Prieto, Lucas

    2015-06-15

    Antivitamins represent a broad class of compounds that counteract the essential effects of vitamins. The symptoms triggered by such antinutritional factors resemble those of vitamin deficiencies, but can be successfully reversed by treating patients with the intact vitamin. Despite being undesirable for healthy organisms, the toxicities of these compounds present considerable interest for biological and medicinal purposes. Indeed, antivitamins played fundamental roles in the development of pioneering antibiotic and antiproliferative drugs, such as prontosil and aminopterin. Their development and optimisation were made possible by the study, throughout the 20th century, of the vitamins' and antivitamins' functions in metabolic processes. However, even with this thorough knowledge, commercialised antivitamin-based drugs are still nowadays limited to antagonists of vitamins B9 and K. The antivitamin field thus still needs to be explored more intensely, in view of the outstanding therapeutic success exhibited by several antivitamin-based medicines. Here we summarise historical achievements and discuss critically recent developments, opportunities and potential limitations of the antivitamin approach, with a special focus on antivitamins K, B9 and B12 . © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  15. Display of nuclear medicine imaging studies

    International Nuclear Information System (INIS)

    Singh, B.; Kataria, S.K.; Samuel, A.M.

    2002-08-01

    Nuclear medicine imaging studies involve evaluation of a large amount of image data. Digital signal processing techniques have introduced processing algorithms that increase the information content of the display. Nuclear medicine imaging studies require interactive selection of suitable form of display and pre-display processing. Static imaging study requires pre-display processing to detect focal defects. Point operations (histogram modification) along with zoom and capability to display more than one image in one screen is essential. This album mode of display is also applicable to dynamic, MUGA and SPECT data. Isometric display or 3-D graph of the image data is helpful in some cases e.g. point spread function, flood field data. Cine display is used on a sequence of images e.g. dynamic, MUGA and SPECT imaging studies -to assess the spatial movement of tracer with time. Following methods are used at the investigator's discretion for inspection of the 3-D object. 1) Display of orthogonal projections, 2) Display of album of user selected coronal/ sagital/ transverse orthogonal slices, 3) Display of three orthogonal slices through user selected point, 4) Display of a set of orthogonal slices generated in the user-selected volume, 5) Generation and display of 3-D shaded surface. 6) Generation of volume data and display along with the 3-D shaded surface, 7) Side by side display orthogonal slices of two 3-D objects. Displaying a set of two-dimensional slices of a 3-D reconstructed object through shows all the defects but lacks the 3-D perspective. Display of shaded surface lacks the ability to show the embedded defects. Volume display -combining the 3-D surface and gray level volume data is perhaps the best form of display. This report describes these forms of display along with the theory. (author)

  16. Nuclear medicine consensus; Consenso sobre medicina nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Camargo, Edwaldo E.; Marin Neto, Jose Antonio; Naccarato, Alberto F.P.; Ramires, Jose Antonio F.; Castro, Iran de; Paiva, Eleuses Vieira; Thom, Anneliese F.; Barroso, Adelanir; Blum, Bernardo; Hollanda, Ricardo; Mansur, Antonio de Padua

    1995-04-01

    The use of nuclear methods in cardiovascular diseases is studied concerning diagnosis, risk, prognosis, indications and accuracy. Aspects concerning chronic coronary artery disease, myocardial ischemia, myocardial infarction, viable myocardium, valvular heart disease, ventricular dysfunction, heart transplant, congenital heart diseases in adults, are discussed.

  17. Nuclear medicine with its interdependencies

    International Nuclear Information System (INIS)

    1980-01-01

    Newly developed nuclear methods and measuring techniques in the diagnosis and therapy of diseases of the blood, heart, vessels, thyroid, gastrointestinal tract, kidneys, skeleton and ophthalmological diseases are described. Occupational radiation exposure is briefly discussed. (AJ) [de

  18. The multiple applications of the nuclear techniques in Argentina

    International Nuclear Information System (INIS)

    Manzini, Alberto C.

    2001-01-01

    A review is given of the use of nuclear technology in Argentina, especially in the field of the production of radioisotopes and radiopharmaceuticals, nuclear medicine, and industrial applications. The applications of ionizing radiation are also reviewed

  19. The state of the art of nuclear medicine in 1980

    International Nuclear Information System (INIS)

    Tamat, S.R.

    1982-01-01

    The second congress of World Federation of Nuclear Medicine and Biology proved that nuclear medicine is returning to physiology. Around 1951, when motorized detector was introduced and when GM tube was replaced by scintillation crystal detector, physiologic nuclear medicine moved to anatomic nuclear medicine. Since 1970, when research on cardiology developed, nuclear medicine has been returning to physiology. Since 1963 Kuhl has been doing research on quantitative tomography which develops to emission computerized tomography emphasizing the physiological aspects of medicine. The recent contribution of nuclear medicine to medical science is the concept that human body is a unity of dynamic structure consisting of millions of cubes moving physio-chemically. (RUW)

  20. Radiation Protection Programme in Nuclear Medicine Practice

    International Nuclear Information System (INIS)

    Alarfaj, Abd-I.M.

    2003-01-01

    This paper specifies the main elements of the radiation protection programma (RPP) that should be estabished for each practice, which involves radiation exposure. Practices of nuclear medicine have been considered as an example, since among the 245 installations which are conducting different practices with radiation sources in the Kingdom of Saudi Arabia, there are 78 installations dealing with nuclear medicine practices. Reviewing the RPP in these nuclear medicine installations, it may be easily concluded that the RPPs for the majority of these installations do not respond to the requirements of the regulatory body of the Kingdom, which is King Abdulaziz City for Science and Technology (KACST). This may be attributed to a set of different reasons, such as shortage in understanding the main elements of the RPP as well as in applying methodologies

  1. Introduction of nuclear medicine research in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Inubushi, Masayuki [Kawasaki Medical School, Division of Nuclear Medicine, Department of Radiology, Kurashiki, Okayama (Japan); Higashi, Tatsuya [National Institutes of Quantum and Radiological Science and Technology, National Institute of Radiological Sciences, Chiba, Chiba (Japan); Kuji, Ichiei [Saitama Medical University International Medical Center, Department of Nuclear Medicine, Hidaka-shi, Saitama (Japan); Sakamoto, Setsu [Dokkyo University School of Medicine, PET Center, Mibu, Tochigi (Japan); Tashiro, Manabu [Tohoku University, Division of Cyclotron Nuclear Medicine, Cyclotron and Radioisotope Center, Sendai, Miyagi (Japan); Momose, Mitsuru [Tokyo Women' s Medical University, Department of Diagnostic Imaging and Nuclear Medicine, Tokyo (Japan)

    2016-12-15

    There were many interesting presentations of unique studies at the Annual Meeting of the Japanese Society of Nuclear Medicine, although there were fewer attendees from Europe than expected. These presentations included research on diseases that are more frequent in Japan and Asia than in Europe, synthesis of original radiopharmaceuticals, and development of imaging devices and methods with novel ideas especially by Japanese manufacturers. In this review, we introduce recent nuclear medicine research conducted in Japan in the five categories of Oncology, Neurology, Cardiology, Radiopharmaceuticals and Technology. It is our hope that this article will encourage the participation of researchers from all over the world, in particular from Europe, in scientific meetings on nuclear medicine held in Japan. (orig.)

  2. Czechoslovak nuclear medicine, development and present state

    Energy Technology Data Exchange (ETDEWEB)

    Hupka, S [Ustav Klinickej Onkologie, Bratislava (Czechoslovakia)

    1981-01-01

    The growth is described of nuclear medicine departments and units in Czechoslovakia in the past 25 years of the existence of the Czechoslovak Society for Nuclear Medicine and Radiation Hygiene, the numbers of personnel and their qualifications. While only three nuclear medicine units were involved in the use of radioisotopes for diagnostic and therapeutic purposes in the 1950's, 29 specialized departments and 15 laboratories are now in existence with a staff of 299 medical doctors and other university graduates and 365 technicians and nurses. They operate all possible instruments, from simple detector devices via gamma cameras to computer tomographs. Briefly, the involvement of the Society is described in coordinated research programs, both with institutions in the country and with the other CMEA countries and IAEA.

  3. Exposure from diagnostic nuclear medicine procedures

    International Nuclear Information System (INIS)

    Iacob, O.; Diaconescu, C.; Isac, R.

    2002-01-01

    According to our last national study on population exposures from natural and artificial sources of ionizing radiation, 16% of overall annual collective effective dose represent the contribution of diagnostic medical exposures. Of this value, 92% is due to diagnostic X-ray examinations and only 8% arise from diagnostic nuclear medicine procedures. This small contribution to collective dose is mainly the result of their lower frequency compared to that of the X-ray examinations, doses delivered to patients being, on average, ten times higher. The purpose of this review was to reassess the population exposure from in vivo diagnostic nuclear medicine procedures and to evaluate the temporal trends of diagnostic usage of radiopharmaceuticals in Romania. The current survey is the third one conducted in the last decade. As in the previous ones (1990 and 1995), the contribution of the Radiation Hygiene Laboratories Network of the Ministry of Health and Family in collecting data from nuclear medicine departments in hospitals was very important

  4. Radiopharmaceutical prescription in nuclear medicine departments

    International Nuclear Information System (INIS)

    Biechlin-Chassel, M.L.; Lao, S.; Bolot, C.; Francois-Joubert, A.

    2010-01-01

    In France, radiopharmaceutical prescription is often discussed depending to which juridical structure the nuclear medicine department is belonging. According to current regulation, this prescription is an obligation in a department linked to hospital with a pharmacy department inside. But situation remains unclear for independent nuclear medicine departments where physicians are not constrained to prescribe radiopharmaceuticals. However, as radiographers and nurses are only authorized to realize theirs acts in front of a medical prescription, one prescription must be realized. Nowadays, computerized prescription tools have been developed but only for radiopharmaceutical drugs and not for medical acts. In the aim to achieve a safer patient care, the prescription regulation may be applied whatever differences between nuclear medicines departments. (authors)

  5. Symposium on nuclear particle accelerators in medicine: abstracts

    International Nuclear Information System (INIS)

    1986-01-01

    This symposium deals with the cyclotron production of radiopharmaceuticals and the application of radionuclides and -pharmaceuticals produced this way. The use of positron emitters in nuclear medicine medical physics and radiobiology are discussed as well as radiotherapy and all the aspects of neutron radiation and dosimetry of neutron therapy

  6. Nuclear Medicine Imaging in Pediatric Infection or Chronic Inflammatory Diseases

    NARCIS (Netherlands)

    Signore, Alberto; Glaudemans, Andor W. J. M.; Gheysens, Olivier; Lauri, Chiara; Catalano, Onofrio A.

    In this review article, we focus on the most recent applications of nuclear medicine techniques (mainly (99m)Tc/(111)In white blood cells (WBC) scan, [(18)F]-FDG-PET/CT, [(18)F]-FDG-PET/MRI, and (99m)Tc-IL-2 scintigraphy) in the study of children affected by peripheral bone osteomyelitis, fungal

  7. Nuclear Medicine in a developing country

    International Nuclear Information System (INIS)

    Wenzel, K.S. von; Rubow, S.M.; Ellmann, A.; Ghoorun, S.

    2002-01-01

    Namibia is a country with 1,8 million inhabitants, of whom the majority has limited access to first world facilities. Nevertheless, medical services of high standard are offered. A Nuclear Medicine Department was established at Windhoek Central Hospital in 1982. A nuclear physician, two nuclear medicine radiographers and a nursing sister staff the department. Equipment includes a Siemens Orbiter and an Elscint Apex SPX Helix gamma camera. Radiopharmaceuticals are obtained from suppliers in South Africa. Investigations performed include musculoskeletal, liver, hepatobiliary, thyroid, renal studies, ventilation perfusion lung scans as well as the following Nuclear Cardiology studies: Gated blood pool scans, Tc-99m pyrophosphate hot spot scans, Tl-201 myocardial perfusion studies, Tc-99m MIBI myocardial perfusion studies and Tl-201 rest-redistribution studies. Problems experienced at the Windhoek Nuclear Medicine department include: Lack of funding and high cost of equipment and radiopharmaceuticals, lack of understanding of Nuclear Medicine by the hospital management and health administrators, and difficulties in procuring short-lived radiopharmaceuticals. Furthermore, the absence of company representatives and spare parts in Namibia leads to loss of time whenever equipment needs to be repaired. Working as the only nuclear medicine physician in a country also poses major problems. Careful management of resources and information drives have helped to sustain the Nuclear Medicine service despite economic problems in the country. Installation of a tele-link between the department in Windhoek Hospital and Tygerberg Hospital in South Africa has greatly assisted to overcome the problem of isolation and lack of back up from fellow specialists. The IAEA has equipped both departments with Hermes workstations (Nuclear Diagnostics) and a tele-link is maintained via modem. The current software provided with the Hermes system is ideally suited to processing of data such as gated

  8. Calibration of nuclear medicine gamma counters

    International Nuclear Information System (INIS)

    Orlic, M.; Spasic-Jokic, V.; Jovanovic, M.; Vranjes, S. . E-mail address of corresponding author: morlic@vin.bg.ac.yu; Orlic, M.)

    2005-01-01

    In this paper the practical problem of nuclear medicine gamma counters calibration has been solved by using dose calibrators CRC-15R with standard error ±5%. The samples from technetium generators have been measured both by dose calibrators CRC-15R and gamma counter ICN Gamma 3.33 taking into account decay correction. Only the linear part of the curve has practical meaning. The advantage of this procedure satisfies the requirements from international standards: the calibration of sources used for medical exposure be traceable to a standard dosimetry laboratory and radiopharmaceuticals for nuclear medicine procedures be calibrated in terms of activity of the radiopharmaceutical to be administered. (author)

  9. Nuclear medicine quality assurance program in Argentina

    International Nuclear Information System (INIS)

    Levi de Cabrejas, Mariana; Arashiro, Jorge G.; Giannone, Carlos A.

    1999-01-01

    A two steps program has been implemented: the first one is the quality control of the equipment and the second one the development of standard procedures for clinical studies of patients. A training program for doctors and technicians of the nuclear medicine laboratories was carried out. Workshops on instrumentation and quality assurance in nuclear medicine have been organized in several parts of the country. A joint program of the CNEA and the University of Buenos Aires has trained medical physicists. A method has been established to evaluate the capability of the laboratories to produce high quality images and to follow up the implementation of the quality control program

  10. Nuclear medicine and the pregnant patient

    International Nuclear Information System (INIS)

    Collins, L.

    1988-01-01

    Estimates of the risks of exposing an embryo or fetus to radiation are discussed. Recommendations are made about the policies a nuclear medicine department should develop for handling cases of accidental irradiation of an embryo or fetus. The choices available where a known pregnancy is involved and diagnostic radiology is required are outlined. Only necessary examinations should be performed and care taken to avoid or minimise irradiation of the fetus. The nuclear medicine physician must be prepared to make (and defend if necessary) an informed decision on whether to proceed with an examination and must also be in a position to discuss the risks with anxious parents

  11. Quality control in paediatric nuclear medicine

    International Nuclear Information System (INIS)

    Fischer, S.; Hahn, K.

    1997-01-01

    Nuclear medicine examinations in children require a maximum in quality. This is true for the preparation of the child and parents, the imaging procedure, processing and documentation. It is necessary that quality control through all steps is performed regularly. The aim must be that the children receive a minimum radiation dose, while there needs to be a high quality in imaging and clinical information from the study. Furthermore the child should not be too much psychologically affected by the nuclear medicine examination. (orig.) [de

  12. Nuclear medicine environmental discharge measurement. Final report

    International Nuclear Information System (INIS)

    Gesell, T.F.; Prichard, H.M.; Davis, E.M.; Pirtle, O.L.; DiPietro, W.

    1975-06-01

    The discharge of most man-made radioactive materials to the environment is controlled by Federal, State or local regulatory agencies. Exceptions to this control include the radioactive wastes eliminated by individuals who have undergone diagnostic or therapeutic nuclear medicine procedures. The purpose of this study is to estimate the amount of radioactivity released to the environment via the nuclear medicine pathway for a single sewage drainage basin and to measure the amounts discharged to the environment. The report is organized into a review of previous studies, scope of work, facility data, environmental measurements and estimates of population exposure

  13. Occupational exposure of nuclear medicine personnel

    International Nuclear Information System (INIS)

    Roessler, M.

    1982-01-01

    The results are given of measurements of the radiation burden of personnel in departments of nuclear medicine in the years 1979 to 1981 using film dosemeters and ring thermoluminescence dosemeters evaluated by the national personnel dosemeter service. The relations are examined of the exposure of hands and the preparation of radiopharmaceuticals and especially their use for examinations. Certain organizational measures are indicated for reducina radiation burden in a laboratory for the preparation of radiopharmaceuticals. The results of measurements and evaluations of radiation burden of personnel of nuclear medicine departments are confronted with conclusions published in the literature. (author)

  14. Diagnosis of liver lesions in nuclear medicine

    International Nuclear Information System (INIS)

    Krause, T.; Juengling, F.

    2003-01-01

    With the introduction of new imaging protocols for ultrasound, computed tomography (CT) and magnetic resonance imaging (MRI), the importance of conventional nuclear medicine diagnostic procedures has changed fundamentally. With the introduction of positron emission tomography (PET) into routine diagnostics, the assessment of tissue-specific function adds on to the modern, morphological imaging procedures and in principle allows for differentiating benign from malignant lesions. The actual clinical value of nuclear medicine procedures for the diagnostic workup of focal liver lesions is discussed. (orig.) [de

  15. Basic requirements of nuclear medicine services

    International Nuclear Information System (INIS)

    Belcher, E.H.

    1992-01-01

    Technological progress in nuclear medicine continues, not always to the immediate advantage of the developing world. The capital expense, operational demands and maintenance requirements of ever more complex equipment, the consequent need for highly trained staff, the necessity to assure regular supplies of costly radioactive materials, all present problems to which compromise or alternative solutions must often be sought. This chapter constitutes an attempt to define the basic requirements for thr practice of nuclear medicine with respect to staff, equipment, accommodation, supplies and supporting services with particular reference to the needs of institutions in developing countries

  16. Basic requirements of nuclear medicine services

    Energy Technology Data Exchange (ETDEWEB)

    Belcher, E H

    1993-12-31

    Technological progress in nuclear medicine continues, not always to the immediate advantage of the developing world. The capital expense, operational demands and maintenance requirements of ever more complex equipment, the consequent need for highly trained staff, the necessity to assure regular supplies of costly radioactive materials, all present problems to which compromise or alternative solutions must often be sought. This chapter constitutes an attempt to define the basic requirements for thr practice of nuclear medicine with respect to staff, equipment, accommodation, supplies and supporting services with particular reference to the needs of institutions in developing countries

  17. Tomography in nuclear medicine. Proceedings of an international symposium

    International Nuclear Information System (INIS)

    1996-01-01

    Single photon emission computed tomography (SPECT) is currently being used universally in clinical practice, while positron emission tomography (PET), originally developed as a technique for research, has also gradually moved from the research laboratory to the clinical environment. However, there are significant differences in nuclear medicine capabilities, especially in tomography, between developed and developing countries. The present status and future prospects of nuclear medicine tomography were the main topics of discussion at this latest international symposium, organized by the IAEA in co-operation with the World Health Organization and held in Vienna from 21 to 25 August 1995. The purpose of the meeting was to share experience and information on new developments and clinical applications of two promising tomographic techniques: SPECT and PET. Eight invited papers and 34 regular papers from 23 countries were presented. In addition, there was a panel discussion on the future and direction of tomography in nuclear medicine for developing countries. Refs, figs, tabs

  18. The medicine of nuclear warfare

    International Nuclear Information System (INIS)

    Eastwood, M.

    1981-01-01

    In this article the immediate physical effects on survivors of a nuclear attack and the problems that might face doctors in providing first aid are considered. Radiation effects including long term and genetic effects and public health hazards facing survivors are discussed. (author)

  19. Nuclear cratering applications

    International Nuclear Information System (INIS)

    Williamson, M.M.

    1969-01-01

    The development of nuclear excavation technology is based on the promise that the relatively inexpensive energy available from thermonuclear explosives can be used to simultaneously break and move age quantities of rock and earth economically and safety. This paper discusses the economic and other advantages of using nuclear excavation for large engineering projects. A brief description of the phenomenology of nuclear excavation is given. Each of the several proposed general applications of nuclear excavation is discussed to include a few specific example of possible nuclear excavation projects. The discussion includes nuclear excavation for harbors, canals, terrain transits, aggregate production, mining and water resource development and conservation. (author)

  20. Nuclear cratering applications

    Energy Technology Data Exchange (ETDEWEB)

    Williamson, M M [U.S. Atomic Energy Commission, Germantown, MD (United States)

    1969-07-01

    The development of nuclear excavation technology is based on the promise that the relatively inexpensive energy available from thermonuclear explosives can be used to simultaneously break and move age quantities of rock and earth economically and safety. This paper discusses the economic and other advantages of using nuclear excavation for large engineering projects. A brief description of the phenomenology of nuclear excavation is given. Each of the several proposed general applications of nuclear excavation is discussed to include a few specific example of possible nuclear excavation projects. The discussion includes nuclear excavation for harbors, canals, terrain transits, aggregate production, mining and water resource development and conservation. (author)

  1. IRSN's expertise about nuclear medicine hospital effluents

    International Nuclear Information System (INIS)

    2009-01-01

    This brief note aims at presenting the radioactivity follow up of hospital effluents performed by the French Institute of Radiation Protection and Nuclear Safety (IRSN). This follow up concerns the radioactive compounds and radiopharmaceuticals used in nuclear medicine, and principally technetium 99 and iodine 131. The IRSN has developed a network of remote measurement systems for the monitoring of sewers and waste water cleaning facilities. Data are compiled in a data base for analysis and subsequent expertise. (J.S.)

  2. Proceedings of the Korean Society Nuclear Medicine Autumn Meeting 2001

    International Nuclear Information System (INIS)

    2001-01-01

    This proceedings contains articles of 2001 autumn meeting of the Korean Society Nuclear Medicine. It was held on November 16-17, 2001 in Seoul, Korea. This proceedings is comprised of 6 sessions. The subject titles of session are as follows: Cancer, Physics of nuclear medicine, Neurology, Radiopharmacy and biology, Nuclear cardiology, General nuclear medicine. (Yi, J. H.)

  3. Nuclear Medicine Imaging Devices. Chapter 11

    Energy Technology Data Exchange (ETDEWEB)

    Lodge, M. A.; Frey, E. C. [Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University, Baltimore, MD (United States)

    2014-12-15

    Imaging forms an important part of nuclear medicine and a number of different imaging devices have been developed. This chapter describes the principles and technological characteristics of the main imaging devices used in nuclear medicine. The two major categories are gamma camera systems and positron emission tomography (PET) systems. The former are used to image γ rays emitted by any nuclide, while the latter exploit the directional correlation between annihilation photons emitted by positron decay. The first section of this chapter discusses the principal components of gamma cameras and how they are used to form 2-D planar images as well as 3-D tomographic images (single photon emission computed tomography (SPECT)). The second section describes related instrumentation that has been optimized for PET data acquisition. A major advance in nuclear medicine was achieved with the introduction of multi-modality imaging systems including SPECT/computed tomography (CT) and PET/CT. In these systems, the CT images can be used to provide an anatomical context for the functional nuclear medicine images and allow for attenuation compensation. The third section in this chapter provides a discussion of the principles of these devices.

  4. Neuroimaging in nuclear medicine: drug addicted brain

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Yong-An; Kim, Dae-Jin [The Catholic University of Korea, Seoul (Korea, Republic of)

    2006-02-15

    Addiction to illicit drugs in one of today's most important social issues. Most addictive drugs lead to irreversible parenchymal changes in the human brain. Neuroimaging data bring to light the pharmacodynamics and pharmacokinetics of the abused drugs, and demonstrate that addiction is a disease of the brain. Continuous researches better illustrate the neurochemical alterations in brain function, and attempt to discover the links to consequent behavioral changes. Newer hypotheses and theories follow the numerous results, and more rational methods of approaching therapy are being developed. Substance abuse is on the rise in Korea, and social interest in the matter as well. On the other hand, diagnosis and treatment of drug addiction is still very difficult, because how the abused substance acts in the brain, or how it leads to behavioral problems in not widely known. Therefore, understanding the mechanism of drug addiction can improve the process of diagnosing addict patients, planning therapy, and predicting the prognosis . Neuroimaging approaches by nuclear medicine methods are expected to objectively judge behavioral and neurochemical changes, and response to treatment. In addition, as genes associated with addictive behavior are discovered, functional nuclear medicine images will aid in the assessment of individuals. Reviewing published literature on neuroimaging regarding nuclear medicine is expected to be of assistance to the management of drug addict patients. What's more, means of applying nuclear medicine to the care of drug addict patients should be investigated further.

  5. Nuclear medicine imaging. An encyclopedic dictionary

    International Nuclear Information System (INIS)

    Thie, Joseph A.

    2012-01-01

    The rapidly growing and somewhat complex area of nuclear medicine imaging receives only limited attention in broad-based medical dictionaries. This encyclopedic dictionary is intended to fill the gap. More than 400 entries of between one and three paragraphs are included, defining and carefully explaining terms in an appropriate degree of detail. The dictionary encompasses concepts used in planar, SPECT, and PET imaging protocols and covers both scanner operations and popular data analysis approaches. In spite of the mathematical complexities in the acquisition and analysis of images, the explanations given are kept simple and easy to understand; in addition, many helpful concrete examples are provided. Nuclear Medicine Imaging: An Encyclopedic Dictionary will be ideal for those who wish to obtain a rapid grasp of a concept beyond a definition of a few words but do not want to resort to a time-consuming search of the reference literature. The almost tutorial-like style accommodates the needs of students, nuclear medicine technologists, and varieties of other medical professionals who interface with specialists within nuclear medicine.

  6. Traumatic Brain Injury: Nuclear Medicine Neuroimaging

    NARCIS (Netherlands)

    Sánchez-Catasús, Carlos A; Vállez Garcia, David; Le Riverend Morales, Eloísa; Galvizu Sánchez, Reinaldo; Dierckx, Rudi; Dierckx, Rudi AJO; Otte, Andreas; de Vries, Erik FJ; van Waarde, Aren; Leenders, Klaus L

    2014-01-01

    This chapter provides an up-to-date review of nuclear medicine neuroimaging in traumatic brain injury (TBI). 18F-FDG PET will remain a valuable tool in researching complex mechanisms associated with early metabolic dysfunction in TBI. Although evidence-based imaging studies are needed, 18F-FDG PET

  7. Neuroimaging in nuclear medicine: drug addicted brain

    International Nuclear Information System (INIS)

    Chung, Yong-An; Kim, Dae-Jin

    2006-01-01

    Addiction to illicit drugs in one of today's most important social issues. Most addictive drugs lead to irreversible parenchymal changes in the human brain. Neuroimaging data bring to light the pharmacodynamics and pharmacokinetics of the abused drugs, and demonstrate that addiction is a disease of the brain. Continuous researches better illustrate the neurochemical alterations in brain function, and attempt to discover the links to consequent behavioral changes. Newer hypotheses and theories follow the numerous results, and more rational methods of approaching therapy are being developed. Substance abuse is on the rise in Korea, and social interest in the matter as well. On the other hand, diagnosis and treatment of drug addiction is still very difficult, because how the abused substance acts in the brain, or how it leads to behavioral problems in not widely known. Therefore, understanding the mechanism of drug addiction can improve the process of diagnosing addict patients, planning therapy, and predicting the prognosis . Neuroimaging approaches by nuclear medicine methods are expected to objectively judge behavioral and neurochemical changes, and response to treatment. In addition, as genes associated with addictive behavior are discovered, functional nuclear medicine images will aid in the assessment of individuals. Reviewing published literature on neuroimaging regarding nuclear medicine is expected to be of assistance to the management of drug addict patients. What's more, means of applying nuclear medicine to the care of drug addict patients should be investigated further

  8. Nuclear medicine in obstetrics and gynecology

    International Nuclear Information System (INIS)

    Patterson, V.N.

    1975-01-01

    The role of radioisotopes for diagnosis and therapy in obstetrics and gynecology are reviewed. A brief history of the development of nuclear medicine is given along with a discussion of basic concepts. Finally a more detailed overview with graphs and pictures is presented for specific techniques

  9. Nuclear medicine and thyroid disease - part II

    International Nuclear Information System (INIS)

    Chatterton, B.E.

    2005-01-01

    Part 1 of this article discussed the anatomy, physiology and basic pathology of the thyroid gland. Techniques of thyroid scanning and a few clinical examples are shown part II Copyright (2005) The Australian and New Zealand Society Of Nuclear Medicine Inc

  10. Nuclear medicine in South Africa : current status

    International Nuclear Information System (INIS)

    Vangu, M.D.T.H.W.

    2004-01-01

    Full text: Nuclear medicine in South Africa has been a full specialty on its own since 1987. It is practiced in almost all teaching hospitals and within the private sector in larger cities. Most of the routine radiopharmaceuticals are domestically manufactured and the main isotope can be obtained from locally produced technetium generators. All the radionuclide imaging devices used in the country are imported. The main vendors are GE, Siemens and Phillips. The majority of radionuclide imaging comprises work from nuclear cardiology and nuclear oncology. Almost all the routine clinical nuclear medicine procedures are performed and some in vitro work is also done, however. Principal therapeutic agents used in the country include radioactive iodine, radioactive iodine MIBG and yttrium. The country still lacks experience in receptors imaging and radioimmunology work and no PET scanner has been purchased yet. The academic institutions are active with participation in national and international congresses and also with publications. Although much remains to be done, the future of nuclear medicine in South Africa does not appear gloomy. (author)

  11. Nuclear medicine in gynecologic oncology: Recent practice

    International Nuclear Information System (INIS)

    Lamki, L.M.

    1987-01-01

    Nuclear medicine tests tell more about the physiological function of an organ that about its anatomy. This is in contrast to several other modalities in current use in the field of diagnostic imaging. Some of these newer modalities, such as computerized tomography (CT), offer a better resolution of the anatomy of the organ being examined. This has caused physicians to drift away from certain nuclear medicine tests, specifically those that focus primarily on the anatomy. When CT scanning is available, for instance, it is no longer advisable to perform a scintigraphic brain scan in search of metastasis;CT scanning is more accurate overall and more likely than a nuclear study to result in a specific diagnosis. In certain cases of diffuse cortical infections like herpes encephalitis, however, a scintiscan is still superior to a CT scan. Today's practice of nuclear medicine in gynecologic oncology may be divided into the three categories - (1) time-tested function-oriented scintiscans, (2) innovations of established nuclear tests, and (3) newer pathophysiological scintistudies. The author discusses here, briefly, each of these categories, giving three examples of each

  12. Basic Physics for Nuclear Medicine. Chapter 1

    Energy Technology Data Exchange (ETDEWEB)

    Podgorsak, E. B. [Department of Medical Physics, McGill University, Montreal (Canada); Kesner, A. L. [Division of Human Health, International Atomic Energy Agency, Vienna (Austria); Soni, P. S. [Medical Cyclotron Facility, Board of Radiation and Isotope Technology, Bhabha Atomic Research Centre, Mumbai (India)

    2014-12-15

    The technologies used in nuclear medicine for diagnostic imaging have evolved over the last century, starting with Röntgen’s discovery of X rays and Becquerel’s discovery of natural radioactivity. Each decade has brought innovation in the form of new equipment, techniques, radiopharmaceuticals, advances in radionuclide production and, ultimately, better patient care. All such technologies have been developed and can only be practised safely with a clear understanding of the behaviour and principles of radiation sources and radiation detection. These central concepts of basic radiation physics and nuclear physics are described in this chapter and should provide the requisite knowledge for a more in depth understanding of the modern nuclear medicine technology discussed in subsequent chapters.

  13. The importance of HIFAR to nuclear medicine

    International Nuclear Information System (INIS)

    Wood, N.R.

    1997-01-01

    Since its official opening on 26 January 1960, the HIFAR research reactor operated by the Australian Nuclear Science and Technology Organisation (ANSTO) at Lucas Heights near Sydney has been used to support an expanding nuclear medicine market. HIFAR has characteristics which make it very suitable for this role and the effect has been to make ANSTO the dominant supplier of reactor-based radiopharmaceuticals in Australia and a significant exporter. While HIFAR has capacity to support limited increased production, its future requires government decisions. The author concluded that the absence of an operational research reactor in Australia and the lack of another local source of neutrons could directly affect the practice of nuclear medicine in the country and the level of presently increasing exports

  14. Introduction to the physics of nuclear medicine

    International Nuclear Information System (INIS)

    Goodwin, P.N.; Rao, D.V.

    1977-01-01

    This book presents the fundamentals of physics as they relate to nuclear medicine in as elementary way as possible. The text concentrates solely on those facts which apply directly to the studies or to the instruments which the physician or technician will be using. After an introductory review of the necessary mathematics, the text examines the structure of matter and the nature of radioactivity. The discussion of nuclear decay processes incorporates information on negative beta decay, gamma emission, positron decay, electron capture and isomeric transitions. Alpha particles, beta particles and photons are explored in the chapter on the interaction of radiation with matter. Scintillation detectors, scanners, gamma cameras, and other imaging devices are all explored in detail. This overview of equipment is followed by a study of radionuclides in nuclear medicine and a review of statistics. The final two chapters are concerned with radiation safety and dosimetry

  15. DosedPet application for Nuclear Medicine: Calculation of the volume of medication needed for PET/CT patient

    International Nuclear Information System (INIS)

    Nascimento, Pedro Augusto do; Rodrigues, Araken dos S. Werneck

    2016-01-01

    This paper presents the application (APP) DosePet that calculates the amount of medicament for PET / CT in patients according to the predetermined radiation dose. The software has been designed using the web MIT App Inventor2 tool for Android platform. The application allows the workers to simulate the amount of radiation still existing in the facilities after the applications, increasing security and reducing exposures, and enable greater efficiency in the use of the radiopharmaceutical. (author)

  16. Radiation exposure of nuclear medicine procedures in Germany

    International Nuclear Information System (INIS)

    Hacker, M.

    2005-01-01

    Nuclear Medicine procedures offer the possibility to detect abnormalities on the basis of physiological and metabolic changes and to treat a growing number of diseases in human beings. However, the use of radiopharmaceuticals for nuclear medicine examinations causes a significant component of the total radiation exposure of populations. In Germany it is an essential task of the Federal Office for Radiation Protection to determinate and assess radiation exposure of the population due to nuclear medicine diagnostics and therapy. An important input for this task is the frequency of nuclear-medical examinations with application of ionising radiation and the radiation exposure of patients related to the various procedures. Additional implementation of age- and gender-specific data today allows more exact risk stratification in focusing on different subgroups of patients. Moreover, the collective effective dose as well as the per caput effective dose of the German population may be estimated and compared with earlier collected data or foreign countries. These data reveal where the indication should be questioned particularly critically and if the dose for the various examinations can be reduced and, thus, contribute to the definition of diagnostic reference levels for nuclear medicine procedures in Germany with the aim of both a sufficient image quality and a minimum of radiation exposure. Exceeding the high- as well as the low-values requires documentation and explanation. (orig.)

  17. The application of radionuclides in medicine

    International Nuclear Information System (INIS)

    Boyd, R.E.; Murray, I.P.C.; Sorby, P.J.; Hetherington, E.L.R.

    1977-01-01

    The authors of this article describe the history of nuclear medicine from its beginning at the end of the 19th century when radioactivity was discovered, basic considerations which describe briefly the properties of radionuclides with special reference to the ones which are suited to medical applications and in general terms the diagnostic techniques that are current. The article also includes a segment on the radionuclide technetium 99m, explaining why it is ideal for organ imaging and how it is utilised in a range of radiopharmaceuticals for investigations into many areas of the human body. The radiation risk to the patient, including tabulated radiation exposures for a few of the more common nuclear medicine studies, is dealt with. The article explains that a greater risk to life from not having the test performed is used as the criterion for justifying whether a nuclear medicine procedure is performed or not. The article finally describes the scope of the techniques and the areas of the body which are routinely examined and are exemplified with numerous illustrations. (J.R.)

  18. The Road to Excellence: : A Case Study of the Application of GMP, ISO 9001 and the EFQM Excellence Model in a Nuclear Medicine Department

    NARCIS (Netherlands)

    van Huizen, L; Ahaus, C.T.B. (Kees)

    2017-01-01

    Definitions are introduced to give insight in the field of work of Quality Management in relation to responsibilities in Nuclear Medicine and Molecular Imaging. A relation model visualizes the relationships. When working on the Road to Quality Excellence. The standards as GMP, GCP, ISO 9001 and EFQM

  19. Recommendation for the application of the guideline for incorporation monitoring in nuclear medicine; Empfehlung fuer die Anwendung der Richtlinie zur Inkorporationsueberwachung in der Nuklearmedizin

    Energy Technology Data Exchange (ETDEWEB)

    Schoenmuth, T. [Verein fuer Kernverfahrenstechnik und Analytik Rossendorf e.V. (VKTA), Dresden (Germany); Dalheimer, A. [Bundesamt fuer Strahlenschutz (Germany); Eckardt, J. [Universitaetsklinikum Muenster (Germany); Eschner, W. [Universitaetsklinikum Koeln (Germany); Kratzel, U. [LfU Bayern (Germany); Lassmann, M. [Universitaetsklinikum Wuerzburg (Germany); Lauterbach, H. [Universitaetsklinikum Jena (Germany); Dettmann, K.

    2009-07-01

    For the use of open radioactive materials in the nuclear medicine a recommendation should give assistance by the judgement of the draught suggested by the user according to the guideline 'Incorporation monitoring' to the responsible authorities. To the evaluation of the requirement for a regular monitoring the document delivers recommendations for incorporation factors or use of threshold value measurements. (orig.)

  20. Nuclear medicine at Brookhaven National Laboratory

    International Nuclear Information System (INIS)

    Atkins, H.L.

    1976-01-01

    The Nuclear Medicine Program at the Brookhaven National Laboratory seeks to develop new materials and methods for the investigation of human physiology and disease processes. Some aspects of this research are related to basic research of how radiopharmaceuticals work. Other aspects are directed toward direct applications as diagnostic agents. It is likely that cyclotron-produced positron emitting nuclides will assume greater importance in the next few years. This can be attributed to the ability to label biologically important molecules with high specific activity without affecting biological activity, using 11 C, 13 N, and 15 O. Large quantities of these short-lived nuclides can be administered without excessive radiation dose and newer instrumentation will permit reconstructive axial tomography, providing truly quantitative display of distribution of radioactivity. The 122 Xe- 122 I generator has the potential for looking at rapid dynamic processes. Another generator, the 68 Ge- 68 Ga generator produces a positron emitter for the use of those far removed from cyclotrons. The possibilities for 68 Ga radiopharmaceuticals are as numerous as those for /sup 99m/Tc diagnostic agents

  1. Fourth congress of the South African Society of Nuclear Medicine

    International Nuclear Information System (INIS)

    1990-01-01

    This seminar contains 68 papers. Sixty three papers were indexed. Five papers were considered out of scope for INIS. The implementation of nuclear medicine in the following fields were discussed: neurology, cardiology, monoclonal antibodies, endocrinology, nuclear medicine physics, and radiopharmacy

  2. Hospital Intranet and Extranet in nuclear medicine

    International Nuclear Information System (INIS)

    Gambini, D.J.; Baum, T.P.; Spector, M.; Dumas, F.; Elgard, M.C.; Collington, M.A.; Barritault, L.

    1997-01-01

    Since two years ago nuclear medicine service of Laennec Hospital has implemented transmission and distribution networks of scintigraphic images. A new stage was reached at present by developing an Intranet and Extranet system for nursing units and other services of nuclear medicine. The Intranet link to the services of Laennec Hospital and AP HP is based on a image server connected to the service gamma camera and, after a possible post-processing, the images are transmitted in PCX format by e-mail, attached to the medical record. For communication between nuclear medicine services, a heavier procedure making use of a program for image processing under inter-file standards has been implemented. To achieve the Extranet link with services and physicians of town, exterior to AP HP, a procedure was installed which allows reaching any nursing unit or town physicians having at their disposal e-mail on a secured network. This procedure will be generalized when the Health secured network, linking the medical bodies to Health insurance institutions, will be operational. The interactive tele-medicine will be achieved by means of a procedure based on Internet cooperative tools (wild cards, video- and vision-conferences) which will permits in all situations an interactive work on all the transmitted patient files

  3. European Association of Nuclear Medicine congress. Abstracts

    International Nuclear Information System (INIS)

    Anon.

    1997-01-01

    To assess the exact place of nuclear medicine studies in the clinical environment in consensus with clinicians and radiologists will probably be our most important task during the coming year. Our society cannot afford unnecessary duplication of diagnostic tests but neither should our patients suffer from the failure to use procedures which could change the outcome of their illness or avoid unnecessary pain and costs because of ignorance, or even worse, self defence by larger and thus stronger pressure groups. Defeatism is as inappropriate as remaining in the splendid isolation of our professional and scientific organisations. There is no place for excessive humbleness either, most of the unnecessary procedures performed in modern medicine lie within the domain of other specialists. It is our duty to participate as actors in the thorough reappraisal of the medical, social and economic context of our activity in the interst of our field and our patients. By confronting our ideas and knowledge with those of others, by using our inventiveness to transfer important results from research laboratories to clinical practice and vice versa, by concentrating on the essential rather than pursuing all possible directions, we will be able to influence positively the future of nuclear medicine. There is no better way to develop our speciality than by understanding the clinical issues, by being able to communicate with our clinical partners and by performing common studies on the clinical impact, cost-efficiency and cost-benefit of nuclear medicine procedures. (orig./AJ)

  4. Lessons from other areas of medical imaging - nuclear medicine

    International Nuclear Information System (INIS)

    McCready, V.R.

    1981-01-01

    Ultrasound and nuclear medicine are similar in that they both have been developed for clinical use in the past decade. Unlike X-ray techniques the success or failure of ultrasound and nuclear medicine depend more upon both the operator and the method of display. Since both ultrasound and nuclear medicine use relatively complicated methods of gathering and displaying information some of the lessons learnt during the development of nuclear medicine can be equally applied to ultrasound techniques. (Auth.)

  5. Checklists for quality assurance and audit in nuclear medicine

    International Nuclear Information System (INIS)

    Williams, E.D.; Harding, L.K.; McKillop, J.H.

    1989-01-01

    A series of checklists are given which aim to provide some guidance to staff in determining whether their working procedures in nuclear medicine are likely to produce a good service and avoid mistakes. The checklists relate to the special equipment used in nuclear medicine departments, radiopharmaceuticals, nuclear medicine staff, services to medical and other hospital staff and finally the service to patients. The checklists are relevant to an average nuclear medicine department performing less than 2000 imaging studies per year. (U.K.)

  6. Nuclear physics and optoelectronics presence in industry, medicine and environment

    International Nuclear Information System (INIS)

    Robu, Maria; Peteu, Gh.

    2000-01-01

    This paper reveals applications of Nuclear Physics and Optoelectronics in numerous fields of interest in industry, medicine, environment. In the first part of the work basic elements are analyzed, among which: - the large possibilities offered by the investigation, analysis and testing techniques based on nuclear physics and optoelectronics; - the superior qualitative and quantitative characteristics of these techniques, with varied applicability in fields from industry, medicine and environment. These applications refers to: - elemental analyses of content and impurities; - non-destructive testing with X and gamma radiations; - investigations with radioactive and activable tracers in trophic chains as for instance, ground-vegetation-products-consumers-environment, including also the systemic pollution factors; - complex investigations in the interface tritium-vegetation-environment-humans; - techniques and radiopharmaceutical products for medical investigations; - determinations and automatic control for levels, density, thickness, humidity, surfaces covering; - monitoring by means of remote sensing for the evaluation of the environment, vegetation and pollution factors; - applications and production of laser and UV installations; - connections through optical fibres resistant to radiations; - imaging and medical bioengineering; - advances in X ray, laser and ultrasonic radiology; - monitoring with radiations beams. In the final part, there are presented examples of optoelectronics and nuclear physics applications in fields in industry, medicine and environment, with special stress on their basic characteristics and efficiency. (authors)

  7. Medical imaging. From nuclear medicine to neuro-sciences

    International Nuclear Information System (INIS)

    2003-03-01

    Nuclear medicine and functional imaging were born of the CEA's ambition to promote and develop nuclear applications in the fields of biology and health. Nuclear medicine is based on the use of radioactive isotopes for diagnostic and therapeutic purposes. It could never have developed so rapidly without the progress made in atomic and nuclear physics. One major breakthrough was the discovery of artificial radioelements by Irene and Frederic Joliot in 1934, when a short-lived radioactive isotope was created for the first time ever. Whether natural or synthetic, isotopes possess the same chemical properties as their non-radioactive counterparts. The only difference is that they are unstable and this instability causes disintegration, leading to radiation emission. All we need are suitable detection tools to keep track of them. 'The discovery of artificial radioelements is at the root of the most advanced medical imaging techniques'. The notion of tracer dates back to 1913. Invented by George de Hevesy, it lies at the root of nuclear medicine. By discovering how to produce radioactive isotopes, Irene and Frederic Joliot provided biology researchers with nuclear tools of unrivalled efficiency. Today, nuclear medicine and functional imaging are the only techniques capable of giving us extremely precise information about living organisms in a non-traumatic manner and without upsetting their balance. Positron emission tomography (PET) and nuclear magnetic resonance imaging (MRI) are the main imaging techniques used at the CEA in its neuro-imaging research activities. These techniques are now developing rapidly and becoming increasingly important not only in the neuroscience world, but also for innovative therapies and cancer treatment. (authors)

  8. Proceedings of the Korean Society Nuclear Medicine Autumn Meeting 2002

    International Nuclear Information System (INIS)

    2002-01-01

    This proceedings contains articles of 2002 autumn meeting of the Korean Society Nuclear Medicine. It was held on November 15-16, 2002 in Seoul, Korea. This proceedings is comprised of 5 sessions. The subject titles of session are as follows: Cancer, Physics of nuclear medicine, Neurology, Radiopharmacy and biology, General nuclear medicine. (Yi, J. H.)

  9. Oncological nuclear medicine: from antibody to PET

    International Nuclear Information System (INIS)

    Tsuneo, Saga; Takako, Furukawa

    2006-01-01

    Department of Diagnostic Imaging has recently established in the Molecular Imaging Center of the National Institute of Radiological Sciences. The major aim of the department is to develop novel molecular imaging probes and to establish functional imaging methods of various cancers. The department consists of three sections; 1) biomolecule section (find out optimal biomolecule as the target of cancer imaging), 2) molecular diagnosis section (develop imaging method using specific molecular probe), and 3) clinical diagnosis section (applying molecular imaging modalities to cancer patients). In the present lecture, I would like to review my experiences in various aspects of cancer imaging using nuclear medicine procedures, which might be important in the research in the new department. The talk includes; 1) characteristics and limitations of cancer targeting with radiolabeled anti-cancer monoclonal antibodies and the attempts to overcome the limitations including pre-targeting strategy, 2 ) application of a newly synthesized polyamine (dendrimer) to the delivery and imaging of oligo-DNA and cancer treatment, 3) transfection of Na '/I - sym-porter gene to add iodide uptake mechanism to non-thyroid cancer cells for the wider application of radioiodine therapy, which is now also used as a promising reporter gene in gene therapy, and 4) basic and clinical study of PET metabolic imaging with fluorodeoxyglucose (FDG) and fluoro-thymidine (FLT) to evaluate the characteristics of various cancers. Although these modalities can not directly visualize molecular processes occurring in cancer cells, we can evaluate the imaging results with the insight of molecular biology, and the experiences of these modalities can be the bases for the future development of molecular imaging of malignant tumors. (author)

  10. Emission of β+ Particles Via Internal Pair Production in the 0+ – 0+ Transition of 90Zr: Historical Background and Current Applications in Nuclear Medicine Imaging

    Directory of Open Access Journals (Sweden)

    Marco D'Arienzo

    2013-03-01

    Full Text Available 90Y is traditionally considered as a pure β– emitter. However, the decay of this radionuclide has a minor branch to the 0+ first excited state of 90Zr at 1.76 MeV, that is followed by a β+/β– emission. This internal pair production has been largely studied in the past because it is generated by a rare electric monopole transition (E0 between the states 0+/0+ of 90Zr. The positronic emission has been recently exploited for nuclear medicine applications, i.e. positron emission tomography (PET acquisitions of 90Y-labelled radiopharmaceuticals, widely used as therapeutic agents in internal radiation therapy. To date, this topic is gaining increasing interest in the radiation dosimetry community, as the possibility of detecting β+ emissions from 90Y by PET scanners may pave the way for an accurate patient-specific dosimetry. This could lead to an explosion in scientific production in this field. In the present paper the historical background behind the study of the internal pair production of the 0+/0+ transition of 90Zr is presented along with most up to date measured branch ratio values. An overview of most recent studies that exploit β+ particles emitted from 90Y for PET acquisitions is also provided.

  11. Scintigraphic instruments and techniques in nuclear medicine

    International Nuclear Information System (INIS)

    Bornand, Bernard; Soussaline, Francoise; CEA, 91 - Orsay

    1978-01-01

    A short survey of data processing techniques in medical scintigraphy is presented. Three lists of abstracts being firstly from reviews, secondly from proceedings, and thirdly of reports and thesis, are presented as an addendum to the bibliography CEA-BIB-214, for the period 1975 up to march 1977. An index of authors and subjects is included. Finally an appendix with 18 patents is attached. Several bibliographical reviews: Excerpta Medica (Nuclear Medicine) Abstract Journal, INIS Atomindex, Nuclear Science Abstracts, together with a number of special journals and documents, recently published, have been used for this work [fr

  12. [Radiopharmacokinetics: Utilization of nuclear medicine

    International Nuclear Information System (INIS)

    Wolf, W.

    1989-01-01

    The work performed in the 1986/1989 period can be characterized as one of testing and documenting that the Radiopharmacokinetic technique is both feasible and applicable to human studies, as well as developing spectroscopic methods for undertaking noninvasive human studies. Main accomplishments include studies which: show that drug targeting can be monitored noninvasively using radiolabeled drugs. The study that documented this finding involved an analysis of the comparative kinetics of biodistribution of 195m Pt-cisplatin to brain tumors, when administered intravenously and intra-arterially; show that such differential targeting of Platinum represents a differential quantity of drug and a differential amount of the active component reaching the target site; show that in vivo NMRS studies of drugs are possible, as documented by our studies of 5-fluorouracil; show that 5-fluorouracil can be trapped in tumors, and that such trapping may be directly correlatable to patient response; show that the radiopharmacokinetic technique can also be used effectively for the study of radiopharmaceuticals used for imaging, as documented in our studies with 99m T c -DMSA

  13. (Radiopharmacokinetics: Utilization of nuclear medicine)

    Energy Technology Data Exchange (ETDEWEB)

    Wolf, W.

    1989-01-01

    The work performed in the 1986/1989 period can be characterized as one of testing and documenting that the Radiopharmacokinetic technique is both feasible and applicable to human studies, as well as developing spectroscopic methods for undertaking noninvasive human studies. Main accomplishments include studies which: show that drug targeting can be monitored noninvasively using radiolabeled drugs. The study that documented this finding involved an analysis of the comparative kinetics of biodistribution of {sup 195m}Pt-cisplatin to brain tumors, when administered intravenously and intra-arterially; show that such differential targeting of Platinum represents a differential quantity of drug and a differential amount of the active component reaching the target site; show that in vivo NMRS studies of drugs are possible, as documented by our studies of 5-fluorouracil; show that 5-fluorouracil can be trapped in tumors, and that such trapping may be directly correlatable to patient response; show that the radiopharmacokinetic technique can also be used effectively for the study of radiopharmaceuticals used for imaging, as documented in our studies with {sup 99m}T{sub c}-DMSA.

  14. Areas control of a nuclear medicine service

    International Nuclear Information System (INIS)

    Silva, Islane C.S.; Silva, Iasmim M.S.; Júnior, Cláudio L.R.; Silva, Isvânia S.; Gonzalez, Kethyllém M.; Melo, Francisca A.; Lima, Fernando R.A.

    2017-01-01

    The measurement of the exposure rate of the sectors of a nuclear medicine service (NMS), with the purpose of establishing safety to the service workers and the public, classifying the areas according to the monitoring is presented. Following the studies on the classifications of the areas of a Nuclear Medicine service provided by the category regulatory standard, 3.05 CNEN-NN, measures were taken in all sectors of the NMS in order to classify the areas in: Free, controlled and supervised according to with the exposure level. As a measurement instrument, a Geiger-Muller counter of the digital type was used. The results obtained show a correlation with the Brazilian norm satisfactorily, referring to the exposure rate of the studied SMN sectors

  15. Directory of computer users in nuclear medicine

    International Nuclear Information System (INIS)

    Erickson, J.J.; Gurney, J.; McClain, W.J.

    1979-09-01

    The Directory of Computer Users in Nuclear Medicine consists primarily of detailed descriptions and indexes to these descriptions. A typical Installation Description contains the name, address, type, and size of the institution and the names of persons within the institution who can be contacted for further information. If the department has access to a central computer facility for data analysis or timesharing, the type of equipment available and the method of access to that central computer is included. The dedicated data processing equipment used by the department in its nuclear medicine studies is described, including the peripherals, languages used, modes of data collection, and other pertinent information. Following the hardware descriptions are listed the types of studies for which the data processing equipment is used, including the language(s) used, the method of output, and an estimate of the frequency of the particular study. An Installation Index and an Organ Studies Index are also included

  16. Directory of computer users in nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Erickson, J.J.; Gurney, J.; McClain, W.J. (eds.)

    1979-09-01

    The Directory of Computer Users in Nuclear Medicine consists primarily of detailed descriptions and indexes to these descriptions. A typical Installation Description contains the name, address, type, and size of the institution and the names of persons within the institution who can be contacted for further information. If the department has access to a central computer facility for data analysis or timesharing, the type of equipment available and the method of access to that central computer is included. The dedicated data processing equipment used by the department in its nuclear medicine studies is described, including the peripherals, languages used, modes of data collection, and other pertinent information. Following the hardware descriptions are listed the types of studies for which the data processing equipment is used, including the language(s) used, the method of output, and an estimate of the frequency of the particular study. An Installation Index and an Organ Studies Index are also included. (PCS)

  17. New developments in nuclear medicine technology

    International Nuclear Information System (INIS)

    Ziegler, S.I.; Pichler, B.J.

    2000-01-01

    During the past few years, there have been new impulses in the development of a number of technologies employed in Nuclear Medicine imaging. These include new scintillation materials, the way of detecting the scintillation light, and completely novel methods to detect gamma rays by means of semiconductor detectors. In addition to combined instrumentation that can be used for SPECT and PET, already in clinical use, combined scintigraphic and anatomic imaging devices are now becoming available, for example SPECT/CT or PET/CT. This review article describes the most important of the new components, part of which have already entered product development and part of which are still in the research phase. The review focus on the employment of modern semiconductor detectors in Nuclear Medicine. (orig.) [de

  18. Assessment of knowledge of general practitioners about nuclear medicine

    International Nuclear Information System (INIS)

    Zakavi, R.; Derakhshan, A.; Pourzadeh, Z.

    2002-01-01

    Nuclear medicine is an important department in most of scientific hospitals in the world. Rapid improvement in the filed of nuclear medicine needs continuing education of medical students. We tried to evaluate the knowledge of general practitioners in the flied of nuclear medicine, hoping that this study help mangers in accurate planning of teaching programs. Methods and materials: We prepared a questionnaire with 14 questions regarding applications of nuclear medicine techniques in different specialities of medicine. We selected questions as simple as possible with considering the most common techniques and best imaging modality in some disease. One question in nuclear cardiology, one in lung disease, two questions in thyroid therapy, another two in gastrointestinal system, two in genitourinary system and the last two in nuclear oncology. Also 4 questions were about general aspects of nuclear medicine. We have another 4 questions regarding the necessity of having a nuclear medicine subject during medical study, the best method of teaching of nuclear medicine and the preferred method of continuing education. Also age, sex, graduation date and university of education of all subjects were recorded. Results: One hundred (General practitioners) were studied. including, 58 male and 42 female with age range of 27-45 years did . About 60% of cases were 27-30 years old and 40 cases were older than 40. Seventy two cases were graduated in the last 5 years. Mashad University was the main university of education 52 cases with Tehran University (16 cases) and Tabriz University (6 cases) in the next ranks. Also 26 cases were graduated from other universities. From four questions in the field of general nuclear nedione 27% were correctly answered to all questions, 37% correctly answered two questions and 10% had correct answered only one question. No correct answer was noted in 26% . correct answer was noted in 80% the held of nuclear cardiology and in 72% in the field of lung

  19. Internal Contamination by 131I in nuclear medicine department

    International Nuclear Information System (INIS)

    Chahed, N.; Mtimet, S.; Hammami, H.; Mhiri, A.

    1998-01-01

    Therapeutic applications in nuclear medicine use high activities of 131 I in sodium iodine liquid from which is volatile at ambient temperature. Besides external exposure there is, for the nuclear medicine personnel, an internal exposure risk induced by 131 iodine inhalation. So we tried to assess this risk among the personnel in a nuclear medicine department. We used direct method for measuring 131 radioactivity in vivo by external counting. Gamma ray detector with a Nal ( TI ) probe positioned near the thyroid gland allows investigation of 131 radioactivity. We realised 34 measurements among the personnel, two times at an interval of one month. The results indicate that an 131 iodine internal contamination is found. Estimated thyroid activities were ranging from 35 to 132 Bq. The highest activities has been found in the thyroid of the technicians involved in the administration of 131 iodine therapy. Therefore this values are lower than norms. This study must lead to the implementation control of the 131 iodine internal contamination in order to optimise the personnel protection in nuclear medicine departments (author)

  20. Extracts from IAEA's Resources Manual in Nuclear Medicine. Part-3: Establishing Nuclear Medicine Services

    International Nuclear Information System (INIS)

    2003-01-01

    In the past, consideration was given to the categories of nuclear medicine ranging from simple imaging or in-vitro laboratories, to more complex departments performing a full range of in-vitro and in-vivo procedures that are also involved in advanced clinical services, training programmes, research and development. In developing countries, nuclear medicine historically has often been an offshoot of pathology, radiology or radiotherapy services. These origins are currently changing as less radioimmunoassay is performed and fully-fledged, independent departments of nuclear medicine are being set up. The trend appears to be that all assays (radioassay or ELISA) are done in a biochemistry laboratory whereas nuclear medicine departments are involved largely in diagnostic procedures, radionuclide therapy and non-imaging in-vitro tests. The level of nuclear medicine services is categorized according to three levels of need: Level 1: Only one gamma camera is needed for imaging purposes. The radiopharmaceutical supply, physics and radiation protection services are contracted outside the centre. Other requirements include a receptionist and general secretarial assistance. A single imaging room connected to a shared reporting room should be sufficient, with a staff of one nuclear medicine physician and one technologist, with back-up. This level is appropriate for a small private practice. Level 2: This is suitable for a general hospital where there are multiple imaging rooms where in-vitro and other non-imaging studies would generally be performed as well as radionuclide therapy. Level 3: his is appropriate for an academic institution where there is a need for a comprehensive clinical nuclear medicine service, human resource development and research programmes. Radionuclide therapy for in-patients and outpatients is provided