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Sample records for nucleaire asn autorise

  1. Reports by the Parliamentary Office for scientific and technological assessment. Wednesday, March 30, 2011. 2010 activity report - Hearing of the Nuclear Safety Authority (ASN) college; Comptes rendus de l' Office Parlementaire d'Evaluation des Choix Scientifiques et Technologiques. Mercredi 30 mars 2011. Rapport d'activite 2010 - Audition du college de l'Autorite de surete nucleaire (ASN)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-03-15

    Members of the French Parliament and representatives of the French nuclear safety authority (ASN) discuss the content of the ASN 2010 activity report, the missions and responsibilities of the ASN in the different fields of exploitation of radioactive materials: nuclear energy and medical care. As far as nuclear energy is concerned, the representatives of the ASN evoke the decennial inspection of the French nuclear reactors, the control of the EPR construction, activities related to fuel cycle, the issue of waste management. As far as medical care is concerned, they address activities in the medical sector, the evolution of the number of events, and the commitment of the ASN in regulation elaboration. These issues are discussed with the members of Parliament

  2. ASN reputation system model

    Science.gov (United States)

    Hutchinson, Steve; Erbacher, Robert F.

    2015-05-01

    Network security monitoring is currently challenged by its reliance on human analysts and the inability for tools to generate indications and warnings for previously unknown attacks. We propose a reputation system based on IP address set membership within the Autonomous System Number (ASN) system. Essentially, a metric generated based on the historic behavior, or misbehavior, of nodes within a given ASN can be used to predict future behavior and provide a mechanism to locate network activity requiring inspection. This will provide reinforcement of notifications and warnings and lead to inspection for ASNs known to be problematic even if initial inspection leads to interpretation of the event as innocuous. We developed proof of concept capabilities to generate the IP address to ASN set membership and analyze the impact of the results. These results clearly show that while some ASNs are one-offs with individual or small numbers of misbehaving IP addresses, there are definitive ASNs with a history of long term and wide spread misbehaving IP addresses. These ASNs with long histories are what we are especially interested in and will provide an additional correlation metric for the human analyst and lead to new tools to aid remediation of these IP address blocks.

  3. ASN annual report 2004

    International Nuclear Information System (INIS)

    2005-01-01

    The Nuclear Safety Authority (ASN) groups the Directorate General for Nuclear Safety and Radiation Protection (DGSNR), reporting to the Ministries for Health, Environment and Industry, and the devolved services of the State on which it relies for nuclear safety and radiation protection supervision, primarily DRIRE, DRASS and DDASS. The main topic of 2004, discussed in this report are: nuclear Safety and Transparency bill, shaping the new ASN, setting up inspection of non-BNI nuclear activities, Radiation protection and monitoring of patients, the safety of the EPR reactor project, the national plan for radioactive waste management, the future of high-level long-lived waste, harmonizing nuclear safety in Europe and ASN international involvement. (A.L.B.)

  4. External PCR, ASN's decision

    International Nuclear Information System (INIS)

    Anon.

    2012-01-01

    The French law imposes in some situations the presence of a person skilled in radiation protection (PCR). This article describes the cases when this person must belong to the staff of the enterprise or when this person may be sub-contracted. For instance in most nuclear facilities the PCR must be on the payroll, for enterprises dedicated to nuclear transport the PCR's job can be sub-contracted. A decision given by the ASN (French Nuclear Safety Authority) sets the minimal requests (in terms of training, job contract, activities) of the sub-contracted PCR. (A.C.)

  5. ASN 2009 annual report

    International Nuclear Information System (INIS)

    2010-01-01

    After a presentation of the roles, missions and organization of the ASN (the French Nuclear safety Authority), this document presents and reports its actions in various domains: ionizing radiations and health and environmental risks (knowledge on these risks and hazards, nuclear activities controlled by the ASN, surveillance of exposures to ionizing radiations), principles and actors of nuclear safety, radioprotection and environment protection control, regulation (general framework, proximity nuclear regulation, nuclear installation legal regime, radioactive material transport regulation, arrangements associated with some risks and some specific activities), control of nuclear activities and exposures to ionizing radiations, situations of radiological emergency, public information, international relationships (objectives in Europe and in the world, relationships within the EU and multilateral relationships, bilateral relationships, international convention, international conferences), regional overview of nuclear safety and radioprotection, medical and non medical uses of ionizing radiations, transport of radioactive materials, EDF nuclear plants, nuclear fuel cycle installations, nuclear research installations and other installations, basic nuclear installation dismantling safety, radioactive wastes and polluted sites. This report also provides presentations of incident and accident classification scales and law texts

  6. ASN annual report 2004; ASN Rapport annuel 2004

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    The Nuclear Safety Authority (ASN) groups the Directorate General for Nuclear Safety and Radiation Protection (DGSNR), reporting to the Ministries for Health, Environment and Industry, and the devolved services of the State on which it relies for nuclear safety and radiation protection supervision, primarily DRIRE, DRASS and DDASS. The main topic of 2004, discussed in this report are: nuclear Safety and Transparency bill, shaping the new ASN, setting up inspection of non-BNI nuclear activities, Radiation protection and monitoring of patients, the safety of the EPR reactor project, the national plan for radioactive waste management, the future of high-level long-lived waste, harmonizing nuclear safety in Europe and ASN international involvement. (A.L.B.)

  7. Decree no. 2005-78 from January 26, 2005, authorizing the Atomic Energy Commission to proceed to the definitive shutdown and dismantling operations of the nuclear facility no.20, named Siloe reactor, in the Grenoble city territory (Isere); Decret no. 2005-78 du 26 janvier 2005, autorisant le Commissariat a l'energie atomique a proceder aux operations de mise a l'arret definitif et de demantelement de l'installation nucleaire de base no.20 denommee reacteur Siloe sur le territoire de la commune de Grenoble (Isere)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-02-15

    On March 19, 2003, the French atomic energy commission (CEA) addressed an authorization demand for the definitive shutdown and dismantling of the Siloe reactor. After a technical and administrative instruction of this demand by the French nuclear safety authority (ASN), a project of decree has been presented on July 6, 2004 at the permanent section of the inter-ministry commission of basic nuclear facilities. The commission gave its favourable judgment which is the object of this decree. (J.S.)

  8. Decree no. 2005-79 from January 26, 2005, authorizing the Atomic Energy Commission to proceed to the definitive shutdown and dismantling operations of the nuclear facility no.21, named Siloette research reactor, in the Grenoble city territory (Isere); Decret no. 2005-79 du 26 janvier 2005, autorisant le Commissariat a l'Energie Atomique a proceder aux operations de mise a l'arret definitif et de demantelement de l'installation nucleaire de base no.21 denommee reacteur de recherche Siloette sur le territoire de la commune de Grenoble (Isere)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-02-15

    On May 26, 2003, the French atomic energy commission (CEA) addressed an authorization demand for the definitive shutdown and dismantling of the Siloette research reactor. After a technical and administrative instruction of this demand by the French nuclear safety authority (ASN), a project of decree has been presented on July 6, 2004 at the permanent section of the inter-ministry commission of basic nuclear facilities. The commission gave its favourable judgment which is the object of this decree. (J.S.)

  9. The French Nuclear Safety Authority - ASN

    International Nuclear Information System (INIS)

    2013-01-01

    The ASN (Nuclear Safety Authority) was created by the act of 13 June 2006 concerning the transparency and safety of nuclear activities. The ASN is an independent administrative body that is in charge of controlling nuclear activities in France. The ASN has a workforce of 471 people and a budget of about 76 millions euros. This article details its missions and how it is organized to cover all the French territory. (A.C.)

  10. The French Nuclear Safety Authority (ASN)

    International Nuclear Information System (INIS)

    Alloso, Ph.

    2011-01-01

    This article presents the statutes, the organization and the missions of the Nuclear Safety Authority (ASN) whose scope includes radiation protection since 2002. Globally ASN is in charge of: -) participating to the making of laws and regulations, -) delivering administrative authorizations, -) controlling the conformity of nuclear installations and activities with the laws and regulations, -) informing the public, and -) reporting on the state of nuclear safety and radiation protection each year. (A.C.)

  11. Plutonium, nuclear fuel; Le plutonium, combustible nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Grison, E [Commissariat a l' Energie Atomique, Fontenay aux Roses (France). Centre d' Etudes Nucleaires, Saclay

    1960-07-01

    A review of the physical properties of metallic plutonium, its preparation, and the alloys which it forms with the main nuclear metals. Appreciation of its future as a nuclear fuel. (author) [French] Apercu sur les proprietes physiques du plutonium metallique, sa preparation, ses alliages avec les principaux metaux nucleaires. Consideration sur son avenir en tant que combustible nucleaire. (auteur)

  12. Synthesis of the report from the IRRS evaluation mission performed at the ASN in April 2009 by 12 international experts under the IAEA coordination

    International Nuclear Information System (INIS)

    2009-01-01

    At the request of the Government authorities of France, an international team of 24 experts visited the Autorite de Surete Nucleaire (ASN), the French regulatory authority for nuclear and radiation safety, in November 2006 to conduct the first full scope Integrated Regulatory Review Service (IRRS) mission. The purpose of the mission was to undertake a peer review of the regulatory body of France against the IAEA Safety Standards and to exchange information and experience on safety regulation. In March 2008 the Government authorities of France requested a follow-up mission to review the measures undertaken following the recommendations and suggestions presented in the report of the November 2006 IRRS mission. The scope of the IRRS follow-up mission covered the regulatory aspects of the facilities and practices regulated by ASN, nuclear power plants, research reactors, fuel cycle facilities, medical practices with further review of radiotherapy, industrial and research activities, waste facilities, decommissioning, remediation, public information and communication and, in addition, it was also extended to cover the application of the Code of Conduct of Safety and Security of Radioactive Sources. The review was conducted from March 29 to April 3 2009 by an IRRS team consisting of 12 senior regulatory experts from 11 Member States, two staff members from the IAEA, one IAEA observer and an IAEA administrative assistant. During the review the team recognized that ASN has taken a number of initiatives to improve its effectiveness and efficiency and that ASN faces new challenges. ASN supplied a package of documentation and a well prepared self-assessment, in advance of the mission, including a status report and an action plan to improve its regulatory effectiveness. Both regulatory technical and policy issues were addressed. The policy issues discussed were: regulatory independence, the relationship between ASN and IRSN and medical issues. The IRRS follow-up mission

  13. Reflection groups established by the ASN

    International Nuclear Information System (INIS)

    Fournier, M.

    2009-01-01

    Recent observations about tritium bio-kinetics in aquatic organisms might change our usual consideration about its radio-toxicity. In order to analyse these observations more thoroughly, the French nuclear safety authority (ASN) decided at the end of the year 2007 to create two independent reflection groups gathering scientists, nuclear operators and associations: the group 'tritium impact' has in charge the establishment of a status of the scientific knowledge relative to tritium sanitary impact, while the group 'defense in depth' has in charge the examination of the technical possibilities of tritium reprocessing and the establishment of a knowledge status of its environmental impact. First meetings of both groups took place in May 2008. Abstract only. (J.S.)

  14. Asn12 and Asn278: Critical Residues for In Vitro Biological Activity of Reteplase

    Directory of Open Access Journals (Sweden)

    Naganath Mandi

    2010-01-01

    Full Text Available Reteplase (rPA is a thrombolytic agent used for the treatment of acute myocardial infarction. We studied the expression of rPA and its selected asparagine mutants after integration into the Pichia genome. Though methanol induction of the native and the rPA mutants showed similar expression levels (~200–250 mg/L, the mutants displayed significant loss of protease activity. Strikingly, the clot lysis activities of these mutants were considerably different. While mutation of Asn12 (N12P of the Kringle 2 domain showed delayed clot lysis activity (1/2=38 min compared to the native rPA (1/2=33 min, a faster rate of clot lysis (1/2=27 min was observed when the Asn278 (N278S of the serine protease domain was mutated. Interestingly, the slowest clot lysis activity (1/2=49 min demonstrated by the double mutant (N12P, N278S suggests the dominant role of Asn12 in regulating the fibrinolytic activity of rPA. The results presented in this paper indicate that the fibrinolytic and the proteolytic activities of rPA are independent of each other.

  15. Skills of Asn inspectors responsible for inspecting pressurised equipment

    International Nuclear Information System (INIS)

    Colonna, F.

    2010-01-01

    ASN relies on the unique competencies of its staff to assure that it can complete its mission of maintaining public health and safety. Since 1975, personnel at ASN Nuclear Pressure Equipment Department have played a major role in the oversight of pressure boundary equipment by verifying that equipment is manufactured in compliance with regulatory requirements. This has called for highly competent individuals trained in a variety of technical and regulatory backgrounds. ASN is meeting the challenge of keeping its staff trained and prepared to continue its oversight of nuclear boilers. This has included ensuring that its organization is welt suited to meet the demands, and relying on third-party experts when necessary. With the implementation of the 2006 transparency law, ASN has taken necessary steps to ensure that it will maintain its high level of expertise going forward. (author)

  16. ASN annual report 2007 - ASN report abstracts on the state of Nuclear Safety and Radiation Protection in France in 2007; ASN rapport annuel 2007

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-07-01

    The 2007 annual report of the French nuclear safety authority (ASN) presents the highlights of the year in the domain of nuclear safety and radiation protection in France. The year 2007 was marked by the implementation of a new legislative and regulatory framework created by the 13 June 2006 Act on transparency and security in the nuclear field (TSN) and the 28 June Act on the sustainable management of radioactive materials and wastes. As in the previous two years, the year was relatively satisfactory from the nuclear safety viewpoint and slightly less so with regard to small-scale nuclear activities. For two years now, the medical field has been marked by the declaration to ASN of a number of serious radiotherapy accidents which have led to several deaths or the need for extensive surgery. The following main topics are reviewed in the document: 1 - the decrees implementing the 'TSN' act and the 'Waste' act; 2 - the new ASN, one year on; 3 - ASN regulatory actions in the field of radiotherapy; 4 - regulation of new installations; 5 - the key issues for regulation of existing installations; 6 - nuclear safety and radiation protection research; 7 - policy for management of the post-accident phase of a radiological emergency; 8 - sites and soils polluted by radioactive materials; 9 - international harmonization of nuclear safety and radiation protection.

  17. ASN annual report 2007 - ASN report abstracts on the state of Nuclear Safety and Radiation Protection in France in 2007; ASN rapport annuel 2007

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-07-01

    The 2007 annual report of the French nuclear safety authority (ASN) presents the highlights of the year in the domain of nuclear safety and radiation protection in France. The year 2007 was marked by the implementation of a new legislative and regulatory framework created by the 13 June 2006 Act on transparency and security in the nuclear field (TSN) and the 28 June Act on the sustainable management of radioactive materials and wastes. As in the previous two years, the year was relatively satisfactory from the nuclear safety viewpoint and slightly less so with regard to small-scale nuclear activities. For two years now, the medical field has been marked by the declaration to ASN of a number of serious radiotherapy accidents which have led to several deaths or the need for extensive surgery. The following main topics are reviewed in the document: 1 - the decrees implementing the 'TSN' act and the 'Waste' act; 2 - the new ASN, one year on; 3 - ASN regulatory actions in the field of radiotherapy; 4 - regulation of new installations; 5 - the key issues for regulation of existing installations; 6 - nuclear safety and radiation protection research; 7 - policy for management of the post-accident phase of a radiological emergency; 8 - sites and soils polluted by radioactive materials; 9 - international harmonization of nuclear safety and radiation protection.

  18. ASN report abstracts on the state of Nuclear Safety and Radiation Protection in France in 2008. ASN annual report 2008

    International Nuclear Information System (INIS)

    2009-01-01

    ASN is an independent administrative authority tasked, on behalf of the state, with regulating nuclear safety and radiation protection in order to protect workers, patients and the environment from the hazards involved in nuclear activities. It also contributes to informing the public. ASN, run by a five-member commission, regulates the whole of the sector, acting in a completely impartial manner. The ASN Commission presents its report on the state of nuclear safety and radiation protection in France in 2008. Contents: A - Introduction: The year 2008. B - Key topics: 1. ASN actions to promote greater transparency; 2. EDF nuclear power plant ageing and operating life: the conditions for continued operation; 3. The prevention of malicious acts; 4. ASN regulation of the radiotherapy sector; 5. Regulating and monitoring the construction of the Flamanville 3 EPR reactor; 6. ASN's international nuclear safety responsibilities; 7. The new nuclear countries; 8. Decommissioning of basic nuclear installations and the low-level, long-lived waste disposal project. C - Overview: 1 - Nuclear activities: ionising radiations and health risks; 2 - Principles and stakeholders in the regulation of nuclear safety and radiation protection; 3 - Regulation; 4 - Regulation of nuclear activities and exposure to ionising radiations; 5 - Environmental protection; 6 - Public information and transparency; 7 - International relations; 8 - Radiological emergencies; 9 - Medical uses of ionising radiations; 10 - Industrial and research activities; 11 - Transport of radioactive materials; 12 - EDF nuclear power plants; 13 - Nuclear fuel cycle installations; 14 - Nuclear research facilities and various nuclear installations; 15 - Safe decommissioning of basic nuclear installations; 16 - Radioactive waste and polluted sites. D - Appendices: List of basic nuclear installations; ASN decisions and opinions published in 2008 in its Official Bulletin; Acronyms, abbreviations and names

  19. A.S.N. regulation of Flamanville 3 EPR construction

    International Nuclear Information System (INIS)

    Limousin, S.

    2009-01-01

    The EPR authorization decree for Flamanville 3 was issued by the French government (decree no. 2007-534) on the 10 April 2007. The construction activities are going on in the manufacturer workshops and at Flamanville site. The decree published in November 2007, and related to the so called TSN law (the nuclear transparency and safety nuclear law published in 2006), specifies that the commissioning licence (the agreement for first fuel load) has to be granted by an ASN decision on the basis of the assessment of the demonstration of the plant safety. In this aim, one part of ASN's work is to review, with its technical sup-port organisation (IRSN), the reactor construction in order to appreciate the safety level of the construction activities. This paper describes ASN's strategy for the regulation of Flamanville 3 EPR construction activities, endorsed by ASN commission at the end of November 2007, and the main events which have occurred on Flamanville site since the beginning of the construction. The article presents the main ASN conclusions of this regulation at this time. (author)

  20. ASN annual report 2007 - ASN report abstracts on the state of Nuclear Safety and Radiation Protection in France in 2007

    International Nuclear Information System (INIS)

    2008-01-01

    The 2007 annual report of the French nuclear safety authority (ASN) presents the highlights of the year in the domain of nuclear safety and radiation protection in France. The year 2007 was marked by the implementation of a new legislative and regulatory framework created by the 13 June 2006 Act on transparency and security in the nuclear field (TSN) and the 28 June Act on the sustainable management of radioactive materials and wastes. As in the previous two years, the year was relatively satisfactory from the nuclear safety viewpoint and slightly less so with regard to small-scale nuclear activities. For two years now, the medical field has been marked by the declaration to ASN of a number of serious radiotherapy accidents which have led to several deaths or the need for extensive surgery. The following main topics are reviewed in the document: 1 - the decrees implementing the 'TSN' act and the 'Waste' act; 2 - the new ASN, one year on; 3 - ASN regulatory actions in the field of radiotherapy; 4 - regulation of new installations; 5 - the key issues for regulation of existing installations; 6 - nuclear safety and radiation protection research; 7 - policy for management of the post-accident phase of a radiological emergency; 8 - sites and soils polluted by radioactive materials; 9 - international harmonization of nuclear safety and radiation protection

  1. Assessment of ASN inspections apart from BNI (Greater South West)

    International Nuclear Information System (INIS)

    Menechal, Ph.

    2008-01-01

    After having recalled recent evolutions of the ASN's organization (the French nuclear safety authority) and its basic missions (regulation elaboration, decisions, control of nuclear activities and installations, public information), the author presents the Bordeaux ASN's department which is in charge of the south-western part of France. He indicates and comments some data illustrating the performed actions and missions. He describes the objectives and procedures of inspection which may depend on the activity (external radiotherapy, interventional radiology, research laboratories). He assesses theses inspections in terms of radioprotection organization, of risk assessment and of definition of regulated areas, of personnel classification and dosimetric follow-on, of training of exposed personnel, of medical follow-on, of radioprotection control, of training of patients to radioprotection, of source management, and of waste and effluent management

  2. Accidental exposures in interventional radiology: lessons learned by the ASN

    International Nuclear Information System (INIS)

    Marchal, C.; Valero, M.

    2009-01-01

    The authors outline that interventional radiology often requires long duration exposures of patients to ionizing radiations and thus stress that interventional radiology must be optimized to improve radioprotection of patients and operators. They notice that investigations performed by the ASN (the French Nuclear Safety Authority) on declared events revealed in some cases a lack of knowledge of devices by users, notably of functionalities allowing the applied doses to be controlled

  3. The decommissioning of nuclear facilities; Le demantelement des installations nucleaires de base

    Energy Technology Data Exchange (ETDEWEB)

    Niel, J.Ch.; Rieu, J.; Lareynie, O.; Delrive, L.; Vallet, J.; Girard, A.; Duthe, M.; Lecomte, C.; Rozain, J.P.; Nokhamzon, J.G.; Davoust, M.; Eyraud, J.L.; Bernet, Ph.; Velon, M.; Gay, A.; Charles, Th.; Leschaeva, M.; Dutzer, M.; Maocec, Ch.; Gillet, G.; Brut, F.; Dieulot, M.; Thuillier, D.; Tournebize, F.; Fontaine, V.; Goursaud, V.; Birot, M.; Le Bourdonnec, Th.; Batandjieva, B.; Theis, St.; Walker, St.; Rosett, M.; Cameron, C.; Boyd, A.; Aguilar, M.; Brownell, H.; Manson, P.; Walthery, R.; Wan Laer, W.; Lewandowski, P.; Dorms, B.; Reusen, N.; Bardelay, J.; Damette, G.; Francois, P.; Eimer, M.; Tadjeddine, A.; Sene, M.; Sene, R

    2008-11-15

    This file includes five parts: the first part is devoted to the strategies of the different operators and includes the following files: the decommissioning of nuclear facilities Asn point of view, decommissioning of secret nuclear facilities, decommissioning at the civil Cea strategy and programs, EDF de-construction strategy, Areva strategy for decommissioning of nuclear facilities; the second one concerns the stakes of dismantling and includes the articles as follow: complete cleanup of buildings structures in nuclear facilities, decommissioning of nuclear facilities and safety assessment, decommissioning wastes management issues, securing the financing of long-term decommissioning and waste management costs, organizational and human factors in decommissioning projects, training for the decommissioning professions: the example of the Grenoble University master degree; the third part is devoted to the management of dismantling work sites and includes the different articles as follow: decommissioning progress at S.I.C.N. plant, example of decommissioning work site in Cea Grenoble: Siloette reactor decommissioning, matters related to decommissioning sites, decommissioning of french nuclear installations: the viewpoint of a specialist company, specificities of inspections during decommissioning: the Asn inspector point of view; the fourth part is in relation with the international approach and includes as follow: IAEA role in establishing a global safety regime on decommissioning, towards harmonization of nuclear safety practices in Europe: W.E.N.R.A. and the decommissioning of nuclear facilities, EPA superfund program policy for decontamination and decommissioning, progress with remediation at Sellafield, progress and experiences from the decommissioning of the Eurochemic reprocessing plant in Belgium, activities of I.R.S.N. and its daughter company Risk-audit I.r.s.n./G.r.s. international in the field of decommissioning of nuclear facilities in eastern countries

  4. The Bacillus subtilis and Bacillus halodurans Aspartyl-tRNA Synthetases Retain Recognition of tRNA(Asn).

    Science.gov (United States)

    Nair, Nilendra; Raff, Hannah; Islam, Mohammed Tarek; Feen, Melanie; Garofalo, Denise M; Sheppard, Kelly

    2016-02-13

    Synthesis of asparaginyl-tRNA (Asn-tRNA(Asn)) in bacteria can be formed either by directly ligating Asn to tRNA(Asn) using an asparaginyl-tRNA synthetase (AsnRS) or by synthesizing Asn on the tRNA. In the latter two-step indirect pathway, a non-discriminating aspartyl-tRNA synthetase (ND-AspRS) attaches Asp to tRNA(Asn) and the amidotransferase GatCAB transamidates the Asp to Asn on the tRNA. GatCAB can be similarly used for Gln-tRNA(Gln) formation. Most bacteria are predicted to use only one route for Asn-tRNA(Asn) formation. Given that Bacillus halodurans and Bacillus subtilis encode AsnRS for Asn-tRNA(Asn) formation and Asn synthetases to synthesize Asn and GatCAB for Gln-tRNA(Gln) synthesis, their AspRS enzymes were thought to be specific for tRNA(Asp). However, we demonstrate that the AspRSs are non-discriminating and can be used with GatCAB to synthesize Asn. The results explain why B. subtilis with its Asn synthetase genes knocked out is still an Asn prototroph. Our phylogenetic analysis suggests that this may be common among Firmicutes and 30% of all bacteria. In addition, the phylogeny revealed that discrimination toward tRNA(Asp) by AspRS has evolved independently multiple times. The retention of the indirect pathway in B. subtilis and B. halodurans likely reflects the ancient link between Asn biosynthesis and its use in translation that enabled Asn to be added to the genetic code. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  5. Impact of the Disruption of ASN3-Encoding Asparagine Synthetase on Arabidopsis Development

    Directory of Open Access Journals (Sweden)

    Laure Gaufichon

    2016-02-01

    Full Text Available The aim of this study was to investigate the role of ASN3-encoded asparagine synthetase (AS, EC 6.3.5.4 during vegetative growth, seed development and germination of Arabidopsis thaliana. Phenotypic analysis of knockout (asn3-1 and knockdown (asn3-2 T-DNA insertion mutants for the ASN3 gene (At5g10240 demonstrated wild-type contents of asparagine synthetase protein, chlorophyll and ammonium in green leaves at 35 days after sowing. In situ hybridization localized ASN3 mRNA to phloem companion cells of vasculature. Young siliques of the asn3-1 knockout line showed a decrease in asparagine but an increase in glutamate. The seeds of asn3-1 and asn3-2 displayed a wild-type nitrogen status expressed as total nitrogen content, indicating that the repression of ASN3 expression had only a limited effect on mature seeds. An analysis of amino acid labeling of seeds imbibed with (15N ammonium for 24 h revealed that asn3-1 seeds contained 20% less total asparagine while 15N-labeled asparagine ((2-15Nasparagine, (4-15Nasparagine and (2,4-15Nasparagine increased by 12% compared to wild-type seeds. The data indicate a fine regulation of asparagine synthesis and hydrolysis in Arabidopsis seeds.

  6. Siloette, Siloe mock-up; Siloette, modele nucleaire de siloe

    Energy Technology Data Exchange (ETDEWEB)

    Delcroix, V; Jeanne, G; Mitault, G; Schulhof, P [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1964-07-01

    Siloette is the Siloe mock-up. The main installations are described: various tanks, building, auxiliaries, control systems... Precis ions are given about precautions taken for using spent fuel elements. (authors) [French] Siloette est le modele nucleaire de SILOE. On decrit ses diverses installations: bassins, batiments, auxiliaires, controle... Des precisions sont donnees sur les precautions prises pour y utiliser des elements uses. (auteurs)

  7. Structural insight into gene transcriptional regulation and effector binding by the Lrp/AsnC family

    NARCIS (Netherlands)

    Thaw, P.; Sedelnikova, S.E.; Muranova, T.; Wiese, S.; Ayora, S.; Alonso, J.C.; Brinkman, A.B.; Akerboom, A.P.; Oost, van der J.; Rafferty, J.B.

    2006-01-01

    The Lrp/AsnC family of transcriptional regulatory proteins is found in both archaea and bacteria. Members of the family influence cellular metabolism in both a global (Lrp) and specific (AsnC) manner, often in response to exogenous amino acid effectors. In the present study we have determined both

  8. Renewal of release and sampling authorizations of the Cattenom nuclear power plant. Complementary note on the authorizations demands of radioactive release; Renouvellement des autorisations de rejets et de prelevements de la centrale nucleaire de Cattenom. Note complementaire sur les demandes d'autorisation de rejets radioactifs

    Energy Technology Data Exchange (ETDEWEB)

    Marignac, Y.; Coeytaux, X

    2003-10-15

    The present note follows the exchanges with the contracting authority, the Cattenom nuclear power plant, during the public hearing stood on the 10. of october 2003 at Cattenom. In the frame of the evaluation of the inquiry file by WISE -Paris, this note constitutes a deepening on the question of authorization demands for the radioactive releases. The elements supplied by E.D.F in the file submitted to the inquiry, and the presentation of these demands and the information complements brought during the meeting of the 10. of october, raise different problems of evaluation and justification relative to the evolution of radioactive release of Cattenom. The note analyses in particular, the increasing of dosimetry impact expected from the progression of real release forecasted by the operator, and the weight linked to the feedback of clad failure problem. It discusses the justification brought by E.D.F. to the standing and even the increasing of liquid tritium release instead of the expected reduction, facing the arguments of the operator to the experience feedback on the park and to the uncertainties on the future progress. (N.C.)

  9. [Conformation analysis of the N-glycosylation site Asn-X-Thr/Ser in glycoproteins].

    Science.gov (United States)

    Avanov, A Ia; Lipkind, G M

    1990-03-01

    Theoretical conformational analysis of oligopeptides CH3CO-Asn-X-Thr-NHCH3 (X = Gly, Ala, Pro), modelling N-glycosylation site, and their glycosylated derivatives CH3CO-(GlcNAc beta 1-4GlcNAc beta 1) Asn-X-Thr-NHCH3 has been carried out. Active conformations of the site are found, corresponding to structural prerequisities of N-glycosylation: Asn residue's position in beta-turn and hydrogen bond formation between side chains of Asn and Thr/Ser residues. In this case the L conformation of the central residue X is most probable. Since Pro residue does not possess this conformation, sequences with X = Pro are not glycosylated. It is shown that glycosylation of the above-mentioned sites is accompanied by reorientation of the Asn residue's side chains.

  10. ASN report on nuclear safety and radioprotection status in France in 2010

    International Nuclear Information System (INIS)

    2011-01-01

    After a general overview of the activity of the ASN (the French nuclear safety authority), of its missions and organisation, this activity report indicates the main events of 2010 concerning the actions performed by the ASN and the activities controlled by the ASN. These both aspects are then detailed. The actions performed by the ASN are dealing with nuclear activities (ionizing radiations and risks for health and for the environment), principles and actors of nuclear safety control, radioprotection and environment protection, regulation, control of nuclear activities and exposures to ionizing radiations, emergency situations, public information, international relationship, regional overview of nuclear safety and radioprotection. The activities controlled by the ASN are the medical uses of ionizing radiations, their non medical uses, the transport of radioactive materials, electronuclear plants, installations related to nuclear fuel cycle, nuclear research installations and other nuclear installations, the safety of nuclear installation dismantling, radioactive wastes and polluted sites

  11. The decisions taken in 2012 by the ASN: additional requirements

    International Nuclear Information System (INIS)

    Lacoste, Andre-Claude; Comets, Marie-Pierre; Dumont, Jean-Jacques; Bourguignon, Michel; Jamet, Philippe

    2012-01-01

    After the publication of conclusions of the Additions Safety Assessments (ECS, evaluations complementaires de surete), this document gathers 32 decisions taken by the ASN in June 2012 which specify additional requirements for EDF nuclear power plants, AREVA installations, and some CEA reactors. These measures will lead to a significant strengthening of safety margins beyond their sizing. These decisions impose huge works to operators. They comprise the implementation of an organisation and the construction of premises resistant to a big event which would affect several installations. Other measures concern a deeper training of agents intervening in case of earthquake or severe accident, robust means of power supply for warehousing pools, efficient means to reduce accidental leakage of different compounds, the storing of fissile materials in an installation sufficiently strong to resist earthquakes, and improvements regarding the flood risk management and sodium fire risk management

  12. Hearing of Mrs Marie-Pierre Comets and Mr Marc Sanson, commissioners of the Nuclear Safety Authority (ASN), as well as Mrs Marie-Claude Dupuis, general manager of the National Agency for the management of radioactive wastes (ANDRA), on the nuclear events in Cadarache

    International Nuclear Information System (INIS)

    2009-01-01

    Representatives of the French Nuclear Safety Authority (ASN, Autorite de Surete Nucleaire) and of the French National Agency for the Management of Radioactive Wastes (ANDRA, Agence nationale pour la gestion des dechets radioactifs) answer questions about an incident which occurred in a workshop, where MOx fuel was produced and which is now being dismantled. It appeared that the amount of plutonium present in the gloveboxes has been largely under-assessed: 8 kg were expected, 22 kg of plutonium have already been recovered, and finally 39 kg might be recovered by the end the dismantling operations. Other issues are addressed like the ANDRA's projects of radioactive material geological storage, their technical and institutional aspects, and then again about the late declaration of the Cadarache incident

  13. The control of nuclear sector; Le controle du nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    The Asn is loaded with the control of the nuclear safety and the radiation protection in France: it provides this control, in the name of the state, to protect the workers, the patients, the public and the environment of the risks in relation with nuclear activities. The control is the core business of Asn. Asn so checks the nuclear basic installations (I.N.B.), since their conception until their dismantling, the pressure equipment specially conceived for these installations, the management of the radioactive waste as well as the transport of radioactive substances. Asn also checks all the industrial and research installations as well as the hospitals where are used ionizing radiations. It is a more recent profession there, because dating the reform of the control of the nuclear power of 2002, which constitutes that of the radiation protection. The first responsibility of the activities at risks falls to the one who begins them. This principle applies to all the sectors checked by Asn: an industrialist is responsible for the safety of the nuclear installations which he exploits, a doctor is responsible for the use of the ionizing radiations which he uses. (N.C.)

  14. Reflection groups established by the ASN; Les groupes de reflexion mis en place par l'ASN

    Energy Technology Data Exchange (ETDEWEB)

    Fournier, M. [ASN, 75 - Paris (France)

    2009-07-01

    Recent observations about tritium bio-kinetics in aquatic organisms might change our usual consideration about its radio-toxicity. In order to analyse these observations more thoroughly, the French nuclear safety authority (ASN) decided at the end of the year 2007 to create two independent reflection groups gathering scientists, nuclear operators and associations: the group 'tritium impact' has in charge the establishment of a status of the scientific knowledge relative to tritium sanitary impact, while the group 'defense in depth' has in charge the examination of the technical possibilities of tritium reprocessing and the establishment of a knowledge status of its environmental impact. First meetings of both groups took place in May 2008. Abstract only. (J.S.)

  15. Effects of Asn318 and Asp87Asn318 mutations on signal transduction by the gonadotropin-releasing hormone receptor and receptor regulation.

    Science.gov (United States)

    Awara, W M; Guo, C H; Conn, P M

    1996-02-01

    GnRH receptor (GnRH-R) contains Asn87 and Asp318 instead of the more frequently observed Asp87 and Asn318 found in other G protein-coupled receptors. In the present study, site-directed mutagenesis was used to introduce Asn318 and Asp87Asn318 into GnRH-R. The effect on coupling and regulation of GnRH-R was studied by stable expression of wild and mutant mouse GnRH-R in the lactotropic GH3 cells; these normally release PRL in response to TRH stimulation. The responses to Buserelin (a metabolically stable GnRH analog) in three different cell lines, M1, N8, and ND1 (expressing wild-type, Asn318 mutant, and Asp87Asn318 mutant mouse GnRH-R, respectively) were compared with that observed in the previously characterized GGH3-1' cells, which stably express rat GnRH-R. The Asn318 and Asp87Asn318 mutations had no measurable effect on ligand binding, but abolished the initial down-regulation of receptor that was observed in M1 and GGH3-1' cells, suggesting that the normal location of Asn87 and Asp318 in GnRH-R is involved in the regulation of GnRH-R. In N8 and ND1 cells, Buserelin-stimulated inositol phosphate (IP) production was attenuated, but the release of both cAMP and PRL was stimulated in a dose- and time-dependent manner. These mutations apparently impaired the coupling between GnRH-R and G proteins involved in IP production, but not those involved in cAMP release. In M1 cells, Buserelin stimulation produced a significant increase in IP production, but neither cAMP nor PRL release was significantly stimulated. These findings are consistent with the previous suggestion that GnRH-stimulated PRL release is mediated by a cAMP second messenger system in transfected GGH3 cells.

  16. ASN report of the status of nuclear safety and radiation protection in France in 2012

    International Nuclear Information System (INIS)

    Chevet, Pierre-Franck; Delmestre, Alain; Bardet, Marie-Christine; Covard, Fabienne; Landrin, Sophie

    2013-01-01

    After a presentation of the French Nuclear Safety Authority (ASN), its missions, some key figures illustrating its activities and its organisation, this report proposes an overview of marking events and of actions undertaken by the ASN after the Fukushima accident. Then, the report proposes a detailed and commented overview of actions undertaken by the ASN in different fields and domains: nuclear activities, principles and actors of nuclear safety and radiation protection control, regulation, control of nuclear activities and of exposures to ionizing radiations, radiological and post-accidental emergency situations, public information and transparency, international relationships, regional overview of nuclear safety and radiation protection. The last part addresses activities controlled by the ASN: medical use of ionizing radiations, industrial, research and veterinary uses and source safety, transport of radioactive materials, electronuclear plants, installations related to nuclear fuel cycle, nuclear research and other nuclear installations, safety of dismantling of base nuclear installations, radioactive wastes and polluted sites

  17. ASN report on nuclear safety and radiation protection in France in 2006, excerpts

    International Nuclear Information System (INIS)

    Lacoste, A.C.

    2007-01-01

    The main topics for the Nuclear Safety Authority (ASN) in 2006 were the following ones. 1) the 2006-686 bill on transparency and security in the nuclear field. This law constitutes an overhaul of the legislative framework applicable to nuclear activities. It creates the Nuclear Safety Authority as an independent administrative authority and defines its tasks. It contains significant advances in terms of transparency. 2) The 2006-739 bill concerning sustainable management of radioactive materials and waste. This law clearly states that the disposal in deep geological formations is the reference solution for high-level, long-lived radioactive wastes. 3) The EPR reactor project safety in which ASN completed technical examination of the preliminary safety case. In November 2006, ASN produced to French Authorities a draft decree concerning the EPR project on the Flamanville site. 4) An international audit of ASN was performed in 2006 by IAEA in order to assess the extent to which the standards IAEA recommends are taken into account and implemented. 5) ASN has contributed to the harmonization of nuclear safety in Europe and at world scale through its contribution to the work of the WENRA association. 6) In 2005 and 2006 4 serious radiotherapy accidents were reported in France. Cancer radiotherapy is a fully justified practice that demands a vigilant supervision of ASN. 7) ASN has amplified its means for informing the public about nuclear safety and radiation protection. And 8) ASN considers that people and organizations are fundamental factors in safety and radiation protection and that significant progress is still to be made in taking into account these factors in nuclear activities. (A.C.)

  18. Structural investigations of the active-site mutant Asn156Ala of outer membrane phospholipase A: Function of the Asn-His interaction in the catalytic triad

    NARCIS (Netherlands)

    Snijder, H.J.; van Eerde, J.H.; Kalk, K.H.; Dekker, N.; Egmond, M.R.; Dijkstra, B.W.

    2010-01-01

    Outer membrane phospholipase A (OMPLA) from Escherichia coli is an integral-membrane enzyme with a unique His-Ser-Asn catalytic triad. In serine proteases and serine esterases usually an Asp occurs in the catalytic triad; its role has been the subject of much debate. Here the role of the uncharged

  19. N-Glycosylation analysis of yeast Carboxypeptidase Y reveals the ultimate removal of phosphate from glycans at Asn368.

    Science.gov (United States)

    B S, Gnanesh Kumar; Surolia, Avadhesha

    2017-05-01

    Carboxypeptidase Y from Saccharomyces cerivisiae was characterized for its site specific N-glycosylation through mass spectrometry. The N-glycopeptides were derived using non specific proteases and are analysed directly on liquid chromatography coupled to ion trap mass spectrometer in tandem mode. The evaluation of glycan fragment ions and the Y 1 ions (peptide+HexNAc) +n revealed the glycan sequence and the corresponding site of attachment. We observed the microheterogeneity in N-glycans such as Man 11-15 GlcNAc 2 at Asn 13 , Man 8-12 GlcNAc 2 at Asn 87 , Man 9-14 GlcNAc 2 at Asn 168 and phosphorylated Man 12-17 GlcNAc 2 as well as Man 11-16 GlcNAc 2 at Asn 368 . The presence of N-glycans with Man <18 GlcNAc 2 indicated that in vacuoles the steady release of mannose/phospho mannose residues from glycans occurs initially at Asn 13 or Asn 168 followed by at Asn 368 . However, glycans at Asn 87 which comprises Man 8-12 residues as reported earlier remain intact suggesting its inaccessibility for a similar processing. This in turn indicates the interaction of the glycan at Asn 87 with the polypeptide chain implicating it in the folding of the protein. Copyright © 2017 Elsevier B.V. All rights reserved.

  20. How a regulator is preparing for reviewing a license application file: The case of ASN

    International Nuclear Information System (INIS)

    Tanguy, Loic

    2014-01-01

    The French Nuclear Safety Authority (ASN) is an independent administrative authority. It prepares regulation pertaining to the management of radioactive waste, monitors the control of safety of basic nuclear installations that produce or treat waste or are involved in their disposal and performs inspections of waste producers (EDF, AREVA, CEA, hospitals, research centres, etc.) and Andra, the French National Radioactive Waste Management Agency. It regulates the overall system set up by Andra for accepting waste from producers and assesses waste management policy and the practices of radioactive waste producers. It reviews license applications and authorises commissioning of nuclear installations. In order to review technical documents, ASN benefits from the expertise of technical support organisations. The French Institute for Radiation Protection and Nuclear Safety (IRSN) is the main such organisation. ASN has been making efforts to diversify its experts for several years. In preparing its decisions, ASN also calls on the opinions and recommendations of seven Advisory Committees of Experts (GPE), with expert knowledge in the areas of waste, nuclear pressure equipment, medical exposure, non-medical radiation protection, reactors, transport, and laboratories and nuclear plants. ASN consults the GPEs in preparing its main decisions. In particular, they review the preliminary, provisional and final safety analysis reports for each nuclear installation. They can also be consulted about changes in regulations or doctrine. (authors)

  1. The control of base nuclear installations; Le controle des installations nucleaires de base (INB)

    Energy Technology Data Exchange (ETDEWEB)

    Anon

    2009-04-15

    The Authority of Nuclear Safety ( A.S.N). presents in this column the current events of the control of the nuclear base installations during november, december 2008 and january 2009, classified by nuclear site. This information is also available in real-time on the A.S.N. web site, www.asn.fr, in the column 'news'. We can consult all the notices of significant incident published as well as the following letters of inspection, the notices of information about the reactors shutdown, press releases and the A.S.N. information notes. (N.C.)

  2. Publication of the inspection follow-up letters of the ASN on its site web asn.gouv.fr; Publication des lettres de suite d'inspection de l'ASN sur son site web asn.gouv.fr

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-01

    Since February 2002, the French authority of nuclear safety (ASN) publishes on its web site (http://www.asn.gouv.fr) the letters addressed to the operators of nuclear facilities at the end of its inspections. The ASN carries out about 700 inspections every year which concern the French nuclear facilities, the central services of nuclear operators or of their suppliers, and the transports of nuclear materials. Each inspection is followed by a follow-up letter which mentions all anomalies noticed during the inspection and eventually asks for some remedial actions or for some complements of information. This document brings together the letters published between february and May 2002 and concerning the on-site inspections of nuclear facilities (EdF nuclear power plants, CEA centers, Cogema facilities, other sites) and the off-site inspections (Andra, transports of nuclear materials). (J.S.)

  3. ASN report on the status of nuclear safety and radiation protection in France in 2015. Extracts

    International Nuclear Information System (INIS)

    2016-01-01

    After a recall of ASN missions, key figures and organisation, an overview of main events for 2015, and a presentation of the French law related to energy transition for a green growth, a first part of this huge document presents actions undertaken by the ASN in 2015 in different fields: ionizing radiations and risks for health and the environment, principles and actors of control of nuclear safety and radiation protection, regulation, control of nuclear activities and of exposures to ionizing radiations, emergency radiological and post-accidental situations, public information transparency and participation, international relationships, regional overview of nuclear safety and radiation protection. The second part addresses activities controlled by the ASN: medical uses of ionizing radiations, industrial, research and veterinary uses and source safety, transportation of radioactive materials, EDF nuclear power plants, installations related to nuclear fuel cycle, various industrial and research installations, safety of basic nuclear installation dismantling, radioactive wastes and polluted sites and soils

  4. The 'Pole Nucleaire Bourgogne' for developing the nuclear components industry

    International Nuclear Information System (INIS)

    Kottmann, G.

    2012-01-01

    The 'Pole Nucleaire Bourgogne' (PNB) is a high-technology and heavy industries cluster in Burgundy with an international calling. It aims at innovating, educating and federating in order to place the French nuclear industry in a leading position. PNB gathers 76 small-, and medium-sized enterprises, most of them operating in the metal sector, in design and in the control/measuring sector. The aim of PNB is to make enterprises work and cooperate on specific topics according to their sectors of activities and their skills. PNB has identified 3 domains of strategical innovations: -) ecological manufacturing and durability of heavy components, -) controls for high performance components, and -) maintenance and dismantling techniques in hostile environments. The various industry sectors represented in PNB allows a cross-fertilization between high-tech industries (aeronautics, energy, transportation)

  5. Treatment of effluent at the Saclay Centre d'Etudes Nucleaires (1960); Le traitement des effluents du Centre d'Etudes Nucleaires de Saclay (1960)

    Energy Technology Data Exchange (ETDEWEB)

    Wormser, G [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1960-07-01

    The Centre d'Etudes Nucleaires at Saclay possesses several installations from which liquid radioactive effluent is rejected, and it has thus been found necessary to construct a station for the purification of radioactive liquids and to settle various chemical, analytical and technological problems. This report describes, in the following order: - the disposal possibilities at the Centre d'Etudes Nucleaires, Saclay, - the effluents produced at the centre, - the set-up for collecting effluent, - treatment of the effluent, - results of these treatments. (author) [French] La presence, au Centre d'Etudes Nucleaires de Saclay, de plusieurs installations susceptibles de rejeter des effluents liquides radioactifs a necessite la construction d'une station d'epuration d'eaux radioactives et la mise au point de differents problemes chimiques, analytiques et technologiques. Dans ce rapport, nous exposerons successivement: - les possibilites de rejet du Centre d'Etudes Nucleaires de Saclay, - les effluents du centre, - le dispositif de collecte des effluents, - le traitement de ces effluents, - les resultats de ces traitements. (auteur)

  6. Solid state chemistry of new polysulphides in A/Sn/S (A = Na, K, Rb ...

    Indian Academy of Sciences (India)

    Administrator

    Solid state chemistry of new polysulphides in A/Sn/S (A = Na, K,. Rb) systems. M SUSEELA DEVI and K VIDYASAGAR. Department of Chemistry, Indian Institute of Technology Madras,. Chennai 600 036, India. Ternary polychalcogenides containing chalocogen–chalcogen bonds are metastable compounds that have been ...

  7. New Promotion Patterns in Italian Universities: Less Seniority and More Productivity? Data from ASN

    Science.gov (United States)

    Marini, Giulio

    2017-01-01

    The new habilitation (ASN), established in Italy in 2010 and launched in 2012, was introduced to filter eligible candidates in the competition of associate and full professorships. Its purpose is to cut off poor candidates on the basis of individual scientific productivity before they might be hired in competitions where patronage may favor them.…

  8. Nuclear explosion and internal contamination; Explosion nucleaire et contamination interne

    Energy Technology Data Exchange (ETDEWEB)

    Aeberhardt, A [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1956-07-01

    By the study of the conditions of internal contamination due to the radioactive mixture produced by a nuclear explosion, the parts played by the relative weights of the different elements and the mode of expression of the doses are considered. Only the knowledge of the weight composition of the contamination mixture and of its evolution as a function of time can provide the required basis for the study of its metabolism in the organism. The curves which give the composition of the fission product mixture - in number of nuclei - - as a function of time - have been established. These curves are applied to some practical examples, particularly relative to the nature of contamination, radiotoxicity of some elements and assessment of hazards. (author) [French] Etudiant les modalites de la contamination interne par les elements radioactifs apparus lors d'une explosion nucleaire, le role de la 'masse' et le mode d'expression des doses sont envisages. La connaissance de la composition en 'masse' du melange contaminant et de son evolution en fonction du temps peut seule apporter les bases necessaires a l'etude de son comportement dans l'organisme. Les courbes donnant la composition du melange de produits de fission - en nombre de noyaux - - en fonction du temps - ont ete etablies. Quelques applications pratiques, relatives en particulier a la nature de la contamination, a la radiotoxicite de certains elements et a l'evaluation de risque, sont envisagees a titre d'exemple. (auteur)

  9. Nuclear study of Melusine; Etude nucleaire de Melusine

    Energy Technology Data Exchange (ETDEWEB)

    Cherot, J [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1959-07-01

    In this report are reviewed - with respect to starting of experiments - the main nuclear characteristics of a 20 per cent enriched uranium lattice, with light water as moderator and reflector. The reactor is to operate at 1 MW. 1) Study of various critical masses. 2) Control. Effectiveness of cadmium. Control rods and of a stainless steel regulating rod. 3) Study of the effect on reactivity of disturbances in the core center. 4) Study of xenon and samarium poisoning. 5) Temperature factor. 6) Heat exchanges in a fuel element. (author) [French] On etudie, dans ce rapport, les principales proprietes nucleaires d'un reseau a uranium enrichi (20 pour cent), dont le moderateur et le reflecteur sont l'eau legere en vue des experiences de demarrage. Ce reacteur devra fonctionner a 1 MW. 1) Etude de diverses masses critiques. 2) Controle. Efficacite des barres de controle en cadmium et d'une barre de reglage en acier inoxydable. 3) Etude de l'effet sur la reactivite de perturbation au centre du coeur. 4) Etude de l'empoisonnement xenon et samarium. 5) Coefficient de temperature. 6) Echanges thermiques dans un element. (auteur)

  10. Scanning Tunneling Microscopy study and unusual transport properties of the topological semimetal a-Sn

    Science.gov (United States)

    Ruan, Jiawei

    Weyl semimetals are new states of quantum matter with topological Weyl nodes near Fermi level in the bulk and Fermi arcs at the surface, which are paid a lot attention in recently years. Here#¬we report another topological semimetal a-Sn., which is double Weyl semimetal in the magnetic field and Dirac semimetal in an appropriate in-plane strain. By combing Landau level spectroscopy and quasiparticle interference, we obtain the linear dispersion near the Dirac point within strain while quadratic band dispersion near Γpoint without strain. We also observe the negative longitudinal magnetoresistance (LMR) in both two system, which is caused by chiral anomaly. However ,the LMR profiles of strained a-Sn have a little rise and then descend while the unstrained one drop directly, which is due to the different type of Weyl semimetal and further confirm our prediction.

  11. ASN report on the status of nuclear safety and radiation protection in France in 2011

    International Nuclear Information System (INIS)

    2012-01-01

    The first part of this huge report proposes a detailed overview of ASN activities in different fields: ionizing radiations related to nuclear activities and risks for health and the environment, principles and actors of nuclear safety control, of radiation protection and of protection of the environment, regulation, control of nuclear activities and exposures to ionizing radiations, emergency situations, public information and transparency, international relationships, regional overview of nuclear safety and radiation protection. The second part addresses the activities controlled by the ASN: medical use of ionizing radiations, non medical use of ionizing radiations, transport of radioactive materials, electronuclear power stations, facilities involved in the nuclear fuel cycle, research facilities and other nuclear installations, the safety of dismantling of nuclear base installations, radioactive wastes and polluted sites and soils

  12. ASN1-encoded asparagine synthetase in floral organs contributes to nitrogen filling in Arabidopsis seeds.

    Science.gov (United States)

    Gaufichon, Laure; Marmagne, Anne; Belcram, Katia; Yoneyama, Tadakatsu; Sakakibara, Yukiko; Hase, Toshiharu; Grandjean, Olivier; Clément, Gilles; Citerne, Sylvie; Boutet-Mercey, Stéphanie; Masclaux-Daubresse, Céline; Chardon, Fabien; Soulay, Fabienne; Xu, Xiaole; Trassaert, Marion; Shakiebaei, Maryam; Najihi, Amina; Suzuki, Akira

    2017-08-01

    Despite a general view that asparagine synthetase generates asparagine as an amino acid for long-distance transport of nitrogen to sink organs, its role in nitrogen metabolic pathways in floral organs during seed nitrogen filling has remained undefined. We demonstrate that the onset of pollination in Arabidopsis induces selected genes for asparagine metabolism, namely ASN1 (At3g47340), GLN2 (At5g35630), GLU1 (At5g04140), AapAT2 (At5g19950), ASPGA1 (At5g08100) and ASPGB1 (At3g16150), particularly at the ovule stage (stage 0), accompanied by enhanced asparagine synthetase protein, asparagine and total amino acids. Immunolocalization confined asparagine synthetase to the vascular cells of the silique cell wall and septum, but also to the outer and inner seed integuments, demonstrating the post-phloem transport of asparagine in these cells to developing embryos. In the asn1 mutant, aberrant embryo cell divisions in upper suspensor cell layers from globular to heart stages assign a role for nitrogen in differentiating embryos within the ovary. Induction of asparagine metabolic genes by light/dark and nitrate supports fine shifts of nitrogen metabolic pathways. In transgenic Arabidopsis expressing promoter Ca MV 35S ::ASN1 fusion, marked metabolomics changes at stage 0, including a several-fold increase in free asparagine, are correlated to enhanced seed nitrogen. However, specific promoter Napin2S ::ASN1 expression during seed formation and a six-fold increase in asparagine toward the desiccation stage result in wild-type seed nitrogen, underlining that delayed accumulation of asparagine impairs the timing of its use by releasing amide and amino nitrogen. Transcript and metabolite profiles in floral organs match the carbon and nitrogen partitioning to generate energy via the tricarboxylic acid cycle, GABA shunt and phosphorylated serine synthetic pathway. © 2017 The Authors The Plant Journal © 2017 John Wiley & Sons Ltd.

  13. Management of long-lived radioactive waste: stakes and ASN actions

    International Nuclear Information System (INIS)

    Dandrieux, G.

    2011-01-01

    Due to the length of time it takes to decay, long-lived radioactive waste will remain a hazard on a timescale beyond the length of a human life, and even of several generations. In the case of this waste, long-term management solutions must be implemented to protect human health and the environment without requiring human intervention. In accordance with requirements under the Law, ANDRA (national agency for the management of radioactive waste) is carrying out research on disposal solutions in deep or subsurface geological formations. Nonetheless, until such repositories become available, ASN (authority for nuclear safety) has a duty to ensure safety at current and future interim storage facilities, as well as the safety of operations to retrieve and package this type of waste. To this end, ASN acts on several levels: it is involved in drawing up regulations and reference texts, at national and international level, it examines safety analysis reports related to radioactive waste management at basic nuclear installations, by means of inspections that it performs at every step in radioactive waste management. In its capacity as joint coordinator of the national plan for the management of nuclear waste and materials (PNGMDR) working group, ASN also plays a very active role in drawing up the provisions of the PNGMDR aimed at improving and optimising radioactive waste management. (author)

  14. The protein C omega-loop substitution Asn2Ile is associated with reduced protein C anticoagulant activity.

    LENUS (Irish Health Repository)

    Preston, Roger J S

    2012-02-01

    We report a kindred with heritable protein C (PC) deficiency in which two siblings with severe thrombosis showed a composite type I and IIb PC deficiency phenotype, identified using commercial PC assays (proband: PC antigen 42 u\\/dl, amidolytic activity 40 u\\/dl, anticoagulant activity 9 u\\/dl). The independent PROC nucleotide variations c.669C>A (predictive of Ser181Arg) and c.131C>T (predictive of Asn2Ile) segregated with the type I and type IIb PC deficiency phenotypes respectively, but co-segregated in the siblings with severe thrombosis. Soluble thrombomodulin (sTM)-mediated inhibition of plasma thrombin generation from an individual with PC-Asn2Ile was lower (endogenous thrombin potential (ETP) 56 +\\/- 1% that of ETP determined without sTM) than control plasma (ETP 15 +\\/- 2%) indicating reduced PC anticoagulant activity. Recombinant APC-Asn2Ile exhibited normal amidolytic activity but impaired anticoagulant activity. Protein S (PS)-dependent anticoagulant activity of recombinant APC-Asn2Ile and binding of recombinant APC-Asn2Ile to endothelial protein C receptor (EPCR) were reduced compared to recombinant wild-type APC. Asn2 lies within the omega-loop of the PC\\/APC Gla domain and this region is critical for calcium-induced folding and subsequent interactions with anionic phospholipids, EPCR and PS. The disruption of these interactions in this naturally-occurring PC variant highlights their collective importance in mediating APC anticoagulant activity in vivo.

  15. Nuclear safety in France in 2001; La surete nucleaire en France en 2001

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-01

    This press dossier summarizes the highlights of nuclear safety in France in 2001: the point-of-view of A.C. Lacoste, director of the French authority of nuclear safety (ASN), the new organisation of the control of nuclear safety and radiation protection, the ASN's policy of transparency, the evolutions of nuclear fuels and the consistency of the fuel cycle, the necessary evolutions of the nuclear crisis management, the harmonizing work of safety approaches carried out by the WENRA association. The following documents are attached in appendixes: the decrees relative to the reformation of the nuclear control in France, the missions of the ASN, the control of nuclear safety and radiation protection in France, the organization of ASN in March 2000, the incidents notified in 2001, the inspections performed in 2001, and the list of the main French nuclear sites. (J.S.)

  16. The control of base nuclear facilities (I.N.B.); Le controle des installations nucleaires de base (INB)

    Energy Technology Data Exchange (ETDEWEB)

    Anon

    2009-02-15

    The Authority of Nuclear Safety ( A.S.N). presents in this column the current events of the control of the nuclear basic installations during august, september, october 2008, classified by nuclear site. This information is also available in real-time on the A.S.N. web site, www.asn.fr, in the column 'news'. We can consult all the notices of significant incident published as well as the following letters of inspection, the notices of information about the reactors shutdown, press releases and the A.S.N. information notes. (N.C.)

  17. THE ANALYSIS TOWARDS STATE APPARATUS COMMISSION ROLE IN ASN MANAGEMENT SYSTEM IN INDONESIA

    Directory of Open Access Journals (Sweden)

    Ajib Rakhmawanto

    2015-05-01

    Full Text Available In administrating bureaurcy business process, professional state apparatus are needed. Law number 5 of 2014 about the state civil apparatus mentions management based on merit that supposed to be supervised by an independen institution: State Apparatuss Commision (KASN. This article aims to analyze the KASN, and identify its task, function, and responsibilities. The analysis showed that KASN was formed to create professional state apparatus and supervise the merit system based management. The function of KASN becomes ineffective considering there is NCSA, an establish body with a role to supervise the ASN management. KASN will cause an overlapping and conflict of interest between the two institutions.

  18. Assessment of patient radiation protection in external radiotherapy departments after inspections performed by the ASN 2008

    International Nuclear Information System (INIS)

    Franchi, Vincent; Marchal, Carole

    2009-10-01

    This report proposes an assessment of patient radiation protection in external radiotherapy. It is based on inter-regional syntheses of inspections performed by the ASN in external radiotherapy departments during 2008. It addresses 6 main themes related to patient radiation protection: human and material resources, organisation of medical physics, training in patient radiation protection, mastering of equipment (maintenance, internal quality controls of medical devices), safety and care quality management (formalization of the patient care process and definition of responsibilities, patient identity control, treatment preparation, and treatment execution), and risk management (a priori risk analysis, declaration, recording and internal processing of dysfunctions, improvements of care quality and safety management system)

  19. ASN.1 notation for exchange of data in computer-based railway control systems

    Directory of Open Access Journals (Sweden)

    Zbigniew ŁUKASIK

    2009-01-01

    Full Text Available Development of railway control systems aims at computerization. In most cases these systems are Distributed Real Time Systems. However, a huge problem in their putting into practice is the lack of interface standardization in the range of data structures and information exchange methods. It results in a variety of solutions, and thus in problems concerning cooperation of systems that come from different software vendors. Specification of protocols for data exchanging applications should therefore be created with the use of generally accepted standards. One of them is ASN.1 (Abstract Syntax Notation One language, which shall be presented in this article.

  20. Changes in FGFR2 amino-acid residue Asn549 lead to Crouzon and Pfeiffer syndrome with hydrocephalus

    Directory of Open Access Journals (Sweden)

    Caroline Apra

    2016-10-01

    Full Text Available Mutations in Fibroblast Growth Factor Receptor II (FGFR2 have been identified in patients with Crouzon and Pfeiffer syndrome, among which rare mutations of the intracellular tyrosine kinase domain. Correlating subtle phenotypes with each rare mutation is still in progress. In Necker-Enfants Malades Hospital, we identified three patients harboring three different pathogenic variants of the same amino acid residue Asn-549 located in this domain: in addition to a very typical crouzonoid appearance, they all developed clinically relevant hydrocephalus, which is an inconstant feature of Crouzon and Pfeiffer syndrome. Overall, FGFR2 tyrosine kinase domain mutations account for 5/67 (7.4% cases in our hospital. We describe a novel mutation, p.Asn549Ser, and new cases of p.Asn549His and p.Asn549Thr mutations, each reported once before. Our three cases of Asn-549 mutations, alongside with rare previously reported cases, show that these patients are at higher risk of hydrocephalus. Clinical and imaging follow-up, with possible early surgery, may help prevent secondary intellectual disability.

  1. Asparaginase treatment side-effects may be due to genes with homopolymeric Asn codons (Review-Hypothesis)

    Science.gov (United States)

    BANERJI, JULIAN

    2015-01-01

    The present treatment of childhood T-cell leukemias involves the systemic administration of prokary-otic L-asparaginase (ASNase), which depletes plasma Asparagine (Asn) and inhibits protein synthesis. The mechanism of therapeutic action of ASNase is poorly understood, as are the etiologies of the side-effects incurred by treatment. Protein expression from genes bearing Asn homopolymeric coding regions (N-hCR) may be particularly susceptible to Asn level fluctuation. In mammals, N-hCR are rare, short and conserved. In humans, misfunctions of genes encoding N-hCR are associated with a cluster of disorders that mimic ASNase therapy side-effects which include impaired glycemic control, dislipidemia, pancreatitis, compromised vascular integrity, and neurological dysfunction. This paper proposes that dysregulation of Asn homeostasis, potentially even by ASNase produced by the microbiome, may contribute to several clinically important syndromes by altering expression of N-hCR bearing genes. By altering amino acid abundance and modulating ribosome translocation rates at codon repeats, the microbiomic environment may contribute to genome decoding and to shaping the proteome. We suggest that impaired translation at poly Asn codons elevates diabetes risk and severity. PMID:26178806

  2. Asparaginase treatment side-effects may be due to genes with homopolymeric Asn codons (Review-Hypothesis).

    Science.gov (United States)

    Banerji, Julian

    2015-09-01

    The present treatment of childhood T-cell leukemias involves the systemic administration of prokaryotic L-asparaginase (ASNase), which depletes plasma Asparagine (Asn) and inhibits protein synthesis. The mechanism of therapeutic action of ASNase is poorly understood, as are the etiologies of the side-effects incurred by treatment. Protein expression from genes bearing Asn homopolymeric coding regions (N-hCR) may be particularly susceptible to Asn level fluctuation. In mammals, N-hCR are rare, short and conserved. In humans, misfunctions of genes encoding N-hCR are associated with a cluster of disorders that mimic ASNase therapy side-effects which include impaired glycemic control, dislipidemia, pancreatitis, compromised vascular integrity, and neurological dysfunction. This paper proposes that dysregulation of Asn homeostasis, potentially even by ASNase produced by the microbiome, may contribute to several clinically important syndromes by altering expression of N-hCR bearing genes. By altering amino acid abundance and modulating ribosome translocation rates at codon repeats, the microbiomic environment may contribute to genome decoding and to shaping the proteome. We suggest that impaired translation at poly Asn codons elevates diabetes risk and severity.

  3. Nuclear program of Iran. Towards de-escalation of a nuclear crisis. Advisory letter; Nucleair programma van Iran. Naar de-escalatie van een nucleaire crisis. Briefadvies

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-04-15

    The Dutch government, partly at the request of the House of Representatives (Second Chamber), the AIV asked to give an opinion about the position of Iran in the region and the role of the nuclear program of Iran in the geopolitical relations, in view of the most recent developments [Dutch] De Nederlandse regering heeft, mede op verzoek van de Tweede Kamer der Staten-Generaal, de AIV gevraagd advies uit te brengen over de positie van Iran in de regio en de rol van het nucleaire programma van Iran in de geopolitieke verhoudingen hierin, mede gelet op de meest recente ontwikkelingen.

  4. Cyclization of the N-Terminal X-Asn-Gly Motif during Sample Preparation for Bottom-Up Proteomics

    DEFF Research Database (Denmark)

    Zhang, Xumin; Højrup, Peter

    2010-01-01

    We, herein, report a novel -17 Da peptide modification corresponding to an N-terminal cyclization of peptides possessing the N-terminal motif of X-Asn-Gly. The cyclization occurs spontaneously during sample preparation for bottom-up proteomics studies. Distinct from the two well-known N-terminal ......We, herein, report a novel -17 Da peptide modification corresponding to an N-terminal cyclization of peptides possessing the N-terminal motif of X-Asn-Gly. The cyclization occurs spontaneously during sample preparation for bottom-up proteomics studies. Distinct from the two well-known N......-terminal cyclizations, cyclization of N-terminal glutamine and S-carbamoylmethylcysteine, it is dependent on pH instead of [NH(4)(+)]. The data set from our recent study on large-scale N(α)-modified peptides revealed a sequence requirement for the cyclization event similar to the well-known deamidation of Asn to iso...

  5. Fessenheim 2: ASN's green light for continuing operation - Beginning of the works for unit 1

    International Nuclear Information System (INIS)

    Anon.

    2013-01-01

    Every 10 years a nuclear power plant operator has to make a re-assessment of the nuclear safety standard of his plant. This re-assessment is made of 2 parts: first the review of the safety conformity and secondly a thorough re-examination of the safety that takes into account today's safety standards and feedback experience from similar plants. This detailed assessment of the safety aims at checking that the consequences of the different aging phenomena are well mastered for the next 10 years at least. At the end of this re-assessment, the ASN (French Nuclear Safety Authorities) decide or not the continuation of plant activity or can prescribe safety improvements. In the case of the unit 2 of the Fessenheim plant that has just finished its third decennial safety re-assessment, the ASN has prescribed the same improvements as for the unit 1, that is to say the reinforcement of the resistance to corium of the foundation raft and an improvement on the emergency cooling system. The works on the unit 1 have begun despite contestation from anti-nuclear associations that question the cost of the safety upgrading (20 to 30 millions euros) while the unit is expected to be decommissioned by end 2016. (A.C.)

  6. Leukaemia risks and exposure to ionizing radiations. ASN seminar, Tuesday, June 9, 2015, report

    International Nuclear Information System (INIS)

    Niel, Jean-Christophe; Samain, Jean-Paul; Colonna, Marc; Maynadie, Marc; Richardson, David; Bey, Pierre; Leuraud, Klervi; Laurier, Dominique; Hemon, Denis; Spycher, Ben; Kosti, Ourania; Bouville, Andre; Grosche, Bernd; Ziegelberger, Gunde; Kesminiene, Ausrele; Clavel, Jacqueline; Smeesters, Patrick; Murith, Christophe

    2015-08-01

    This seminar aims at proposing a review of present knowledge on leukaemia risks for children and adults associated with ionizing radiations, and at sharing knowledge between experts. After an introduction which outlined the interest of the ASN in research issues, and the importance awarded by the ASN to the variety of points of view, a first session addressed leukaemia and exposures to ionizing radiations. The contributions addressed some general aspects (an overview of leukaemia in France, the different types of adult and child leukaemia), leukaemia and acute exposures to ionizing radiations (ionizing radiation and leukaemia among Japanese bomb survivors, risks of leukaemia after radiotherapy), leukaemia and chronic exposures to ionizing radiations (assessment of epidemiological studies for adult chronic exposures). The second session addressed childhood leukaemia and ionizing radiations. The contributions of this second session more particularly addressed the following topics: childhood leukaemia and natural radioactivity (French studies, synthesis of international studies and a new Swiss study), childhood leukaemia and proximity of nuclear base installations (assessment of national and international studies, analysis of cancer risks in populations near nuclear facilities in the US, calculation of dose at the medulla as example of dosimetry of ionizing radiations and leukaemia, conclusions of the 2012 MELODI workshop), childhood leukaemia and scanner (recent results and perspectives), childhood leukaemia and other risk factors (etiology of childhood leukaemia - presentation of French studies initiated by the INSERM, and presentation of studies initiated by BfS)

  7. The formal notices of the French authority of nuclear safety; Les mises en demeure de l'autorite de surete nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-01

    The French authority of nuclear safety (ASN) publishes on its web site (http://www.asn.gouv.fr) the formal notices and official statements addressed by the ASN to the concerned responsible persons (operators of nuclear facilities, directors of companies etc..) when anomalies requiring a corrective action have been noticed during on-site or off-site safety inspections. This document brings together the formal notices addressed by the ASN since June 2000 and up to April 2002. (J.S.)

  8. France's nuclear power programme; Le programme nucleaire francais

    Energy Technology Data Exchange (ETDEWEB)

    Cabanius, J [Electricite de France (EDF), 75 - Paris (France); Horowitz, J [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-07-01

    -increasing importance, by using the country's resources of natural uranium, and later plutonium, to the best ends. (authors) [French] Les perspectives d'evolution de la consommation d'energie electrique francaise confirment l'aggravation du deficit des ressources energetiques metropolitaines. Les centrales nucleaires doivent permettre de diminuer ce deficit si un certain nombre d'incertitudes actuelles sont levees. Le premier programme presente par MM AILLERET et TARANGER a la Conference de Geneve en 1955 visait la mise en service pour 1965 de 850 MWe; il a ete consacre au developpement de la filiere uranium naturel - graphite - gaz et s'acheve avec la realisation d'EDF 3, premiere unite capable de 500 MWe engagee dans le monde. Avant de passer du stade des prototypes a celui des duplications, ELECTRICITE DE FRANCE a decide, en accord avec le COMMISSARIAT A L'ENERGIE ATOMIQUE, la realisation d'EDF 4 qui, en reprenant la partie reacteur d'EDF 3 ainsi que l'appareil de chargement et de dechargement, l'ensemble de controle et divers materiels, apporte une innovation importante en incorporant les echangeurs et les soufflantes a l'interieur du caisson en beton precontraint contenant le coeur. En meme temps, les etudes se poursuivent dans cette meme filiere et laissent entrevoir les possibilites d'utiliser un nouvel element combustible annulaire dont l'emploi ameliorerait notablement les performances d'EDF 5. Dans la filiere eau lourde, la realisation d'EL 4 a Brennilis par le COMMISSARIAT A L'ENERGIE ATOMIQUE et ELECTRICITE DE FRANCE se poursuit. Les etudes d'un reacteur de 500 MWe de cette filiere ont deja commence. Dans la filiere a eau pressurisee, la centrale de CHOOZ est realisee en association par ELECTRICITE DE FRANCE et les Producteurs Belges. Enfin, le COMMISSARIAT A L'ENERGIE ATOMIQUE poursuit a Cadarache la realisation du surgenerateur 'Rapsodie' et les etudes d'un reacteur de puissance plus important. Ainsi, les connaissances techniques et economiques acquises dans ces diverses

  9. Polymorphisms in XPD (Asp312Asn and Lys751Gln) genes, sunburn and arsenic-related skin lesions.

    Science.gov (United States)

    McCarty, Kathleen M; Smith, Thomas J; Zhou, Wei; Gonzalez, Ernesto; Quamruzzaman, Quazzi; Rahman, Mahmuder; Mahiuddin, Golam; Ryan, Louise; Su, Li; Christiani, David C

    2007-08-01

    Single-nucleotide polymorphisms in genes related to DNA repair capacity and ultraviolet exposure have not been well investigated in relation to skin lesions associated with arsenic exposure. This population based case-control study, of 600 cases and 600 controls, frequency matched on age and gender in Pabna, Bangladesh, in 2001-2002, investigated the association and potential effect modification between polymorphisms in Xeroderma Pigmentosum complementation group D (XPD) (Lys751Gln and Asp312Asn) genes, tendency to sunburn and arsenic-related skin lesions. Unconditional logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs). No significant association was observed between skin lesions and the XPD 312 Asp/Asn (adjusted OR = 0.87, 95% CI = 0.65-1.15) Asn/Asn (adjusted OR = 0.76, 95% CI = 0.50-1.15) (referent Asp/Asp); XPD 751 Lys/Gln (adjusted OR = 0.92, 95% CI = 0.69-1.23) Gln/Gln (adjusted OR = 0.98, 95% CI = 0.66-1.45) (referent Lys/Lys). While we did not observe any evidence of effect modification of these polymorphisms on the association between well arsenic concentration and skin lesions, we did observe effect modification between these polymorphisms and sunburn tendency and arsenic-related skin lesions. Individuals with the heterozygote or homozygote variant forms (Asp/Asn or Asn/Asn) had half the risk of skin lesions (OR = 0.45, 95% CI = 0.29-0.68) compared with those with the wild-type XPDAsp312Asn genotype (Asp/Asp) and individuals with heterozygote or homozygote variant forms (Lys/Gln or Gln/Gln) had half the risk of skin lesions (OR = 0.47, 95% CI = 0.31-0.72) compared with those with the wild-type XPDLys751Gln genotype (Lys/Lys), within the least sensitive strata of sunburn severity. We observed effect modification on the multiplicative scale for XPD 751 and XPD 312. XPD polymorphisms modified the relationship between tendency to sunburn and skin lesions in an arsenic exposed population. Further study is necessary

  10. Reports by the Parliamentary Office for scientific and technological assessment. Wednesday, March 30, 2011. 2010 activity report - Hearing of the Nuclear Safety Authority (ASN) college

    International Nuclear Information System (INIS)

    2011-03-01

    Members of the French Parliament and representatives of the French nuclear safety authority (ASN) discuss the content of the ASN 2010 activity report, the missions and responsibilities of the ASN in the different fields of exploitation of radioactive materials: nuclear energy and medical care. As far as nuclear energy is concerned, the representatives of the ASN evoke the decennial inspection of the French nuclear reactors, the control of the EPR construction, activities related to fuel cycle, the issue of waste management. As far as medical care is concerned, they address activities in the medical sector, the evolution of the number of events, and the commitment of the ASN in regulation elaboration. These issues are discussed with the members of Parliament

  11. Lack of association between urotensin-II (UTS2 gene polymorphisms (Thr21Met and Ser89Asn and migraine

    Directory of Open Access Journals (Sweden)

    Betül Ozan

    2017-08-01

    Full Text Available Migraine is a common neurovascular brain disorder with heterogeneous clinical presentation, including recurrent headache attacks. The pathophysiology of migraine is complex, and a number of genomic regions have been associated with the development of migraine. In this study, we analyzed the allele and genotype frequencies of the urotensin-II gene (UTS2 polymorphisms, Thr21Met and Ser89Asn, among Turkish patients with migraine. A total of 146 patients with migraine (14 with aura [MA group] and 132 without aura [MO group] were genotyped for Thr21Met and Ser89Asn polymorphisms and compared with 154 age- and sex-matched healthy controls. The UTS2 gene polymorphisms were analyzed by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP. No significant differences were observed in allele and genotype frequencies for Thr21Met and Ser89Asn polymorphisms between the patients with migraine and control group. Similarly, we did not observe significant differences in allele and genotype frequencies between MA and MO and control group. Moreover, the haplotype analysis showed no association between UTS2 gene haplotypes (MN, MS, TN, and TS and migraine. In summary, Thr21Met and Ser89Asn polymorphisms of the UTS2 gene are not risk factors for migraine in our sample of Turkish migraine patients.

  12. A lipoprotein lipase mutation (Asn291Ser) is associated with reduced HDL cholesterol levels in premature atherosclerosis

    NARCIS (Netherlands)

    Reymer, P.W.A.; Gagné, S E; Groenemeyer, B E; Zhang, H; Forsyth, I; Jansen, H; Seidell, J C; Kromhout, D.; Lie, K E; Kastelein, J.J.

    1995-01-01

    A reduction of high density lipoprotein cholesterol (HDC) is recognized as an important risk factor for coronary artery disease (CAD). We now show in approximately 1 in 20 males with proven atherosclerosis that an Asn291Ser mutation in the human lipoprotein lipase (LPL) gene is associated with

  13. The ASN imposes on EDF complementary requirements for the setting of the hard-core unit

    International Nuclear Information System (INIS)

    Anon.

    2014-01-01

    In January 2014, the ASN (French Authority for Nuclear Safety) published a list of 19 decisions concerning the implementation of a 'post-Fukushima' hard-core unit in each EDF nuclear power plant. The purpose of the hard-core unit is to have structures and equipment able to resist very extreme events and able to assure the vital functions necessary for the reactor safety. The 19 decisions detail the rules for the design of the hard-core unit. For example the hard-core unit will have to resist earthquakes for which the probability of occurrence is about 1 every 20.000 years while the probability taking into account for the design of the reactor is only 1 every 1000 or 10.000 years

  14. Glycosylation at Asn91 of H1N1 haemagglutinin affects binding to glycan receptors.

    Science.gov (United States)

    Jayaraman, Akila; Koh, Xiaoying; Li, Jing; Raman, Rahul; Viswanathan, Karthik; Shriver, Zachary; Sasisekharan, Ram

    2012-06-15

    The glycoprotein HA (haemagglutinin) on the surface of influenza A virus plays a central role in recognition and binding to specific host cell-surface glycan receptors and in fusion of viral membrane to the host nuclear membrane during viral replication. Given the abundance of HA on the viral surface, this protein is also the primary target for host innate and adaptive immune responses. Although addition of glycosylation sites on HA are a part of viral evolution to evade the host immune responses, there are specific glycosylation sites that are conserved during most of the evolution of the virus. In the present study, it was demonstrated that one such conserved glycosylation site at Asn(91) in H1N1 HA critically governs the glycan receptor-binding specificity and hence would potentially impinge on the host adaptation of the virus.

  15. ASN guide project. Safety policy and management in INBs (base nuclear installations)

    International Nuclear Information System (INIS)

    2010-01-01

    This guide presents the recommendations of the French Nuclear Safety Authority (ASN) in the field of safety policy and management (PMS) for base nuclear installations (INBs). It gives an overview and comments of some prescriptions of the so-called INB order and PMS decision. These regulatory texts define a framework for provisions any INB operator must implement to establish his safety policy, to define and implement a system which allows the safety to be maintained, the improvement of his INB safety to be permanently looked for. The following issues are addressed: operator's safety policy, identification of elements important for safety, of activities pertaining to safety, and of associated requirements, safety management organization and system, management of activities pertaining to safety, documentation and archiving

  16. Mutation of Asn28 Disrupts the Dimerization and Enzymatic Activity of SARS 3CL

    Energy Technology Data Exchange (ETDEWEB)

    Barrila, J.; Gabelli, S; Bacha, U; Amzel, M; Freire, E

    2010-01-01

    Coronaviruses are responsible for a significant proportion of annual respiratory and enteric infections in humans and other mammals. The most prominent of these viruses is the severe acute respiratory syndrome coronavirus (SARS-CoV) which causes acute respiratory and gastrointestinal infection in humans. The coronavirus main protease, 3CL{sup pro}, is a key target for broad-spectrum antiviral development because of its critical role in viral maturation and high degree of structural conservation among coronaviruses. Dimerization is an indispensable requirement for the function of SARS 3CL{sup pro} and is regulated through mechanisms involving both direct and long-range interactions in the enzyme. While many of the binding interactions at the dimerization interface have been extensively studied, those that are important for long-range control are not well-understood. Characterization of these dimerization mechanisms is important for the structure-based design of new treatments targeting coronavirus-based infections. Here we report that Asn28, a residue 11 {angstrom} from the closest residue in the opposing monomer, is essential for the enzymatic activity and dimerization of SARS 3CLpro. Mutation of this residue to alanine almost completely inactivates the enzyme and results in a 19.2-fold decrease in the dimerization K{sub d}. The crystallographic structure of the N28A mutant determined at 2.35 {angstrom} resolution reveals the critical role of Asn28 in maintaining the structural integrity of the active site and in orienting key residues involved in binding at the dimer interface and substrate catalysis. These findings provide deeper insight into complex mechanisms regulating the activity and dimerization of SARS 3CL{sup pro}.

  17. HOST GALAXY PROPERTIES OF THE SUBLUMINOUS GRB 120422A/SN 2012bz

    Energy Technology Data Exchange (ETDEWEB)

    Levesque, Emily M. [CASA, Department of Astrophysical and Planetary Sciences, University of Colorado 389-UCB, Boulder, CO 80309 (United States); Chornock, Ryan; Soderberg, Alicia M.; Berger, Edo; Lunnan, Ragnhild, E-mail: Emily.Levesque@colorado.edu [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States)

    2012-10-20

    GRB 120422A is a nearby (z = 0.283) long-duration gamma-ray burst (LGRB) detected by Swift with E {sub {gamma},iso} {approx} 4.5 Multiplication-Sign 10{sup 49} erg. It is also associated with the spectroscopically confirmed broad-lined Type Ic SN 2012bz. These properties establish GRB 120422A/SN 2012bz as the sixth and newest member of the class of subluminous GRBs supernovae (SNe). Observations also show that GRB 120422A/SN 2012bz occurred at an unusually large offset ({approx}8 kpc) from the host galaxy nucleus, setting it apart from other nearby LGRBs and leading to speculation that the host environment may have undergone prior interaction activity. Here, we present spectroscopic observations using the 6.5 m Magellan telescope at Las Campanas. We extract spectra at three specific locations within the GRB/SN host galaxy, including the host nucleus, the explosion site, and the 'bridge' of diffuse emission connecting these two regions. We measure a metallicity of log(O/H) + 12 = 8.3 {+-} 0.1 and a star formation rate (SFR) per unit area of 0.08 M {sub Sun} yr{sup -1} kpc{sup -2} at the host nucleus. At the GRB/SN explosion site we measure a comparable metallicity of log(O/H) + 12 = 8.2 {+-} 0.1 but find a much lower SFR per unit area of 0.01 M {sub Sun} yr{sup -1} kpc{sup -2}. We also compare the host galaxy of this event to the hosts of other LGRBs, including samples of subluminous LGRBs and cosmological LGRBs, and find no systematic metallicity difference between the environments of these different subtypes.

  18. Transposon mutagenesis of probiotic Lactobacillus casei identifies asnH, an asparagine synthetase gene involved in its immune-activating capacity.

    Science.gov (United States)

    Ito, Masahiro; Kim, Yun-Gi; Tsuji, Hirokazu; Takahashi, Takuya; Kiwaki, Mayumi; Nomoto, Koji; Danbara, Hirofumi; Okada, Nobuhiko

    2014-01-01

    Lactobacillus casei ATCC 27139 enhances host innate immunity, and the J1 phage-resistant mutants of this strain lose the activity. A transposon insertion mutant library of L. casei ATCC 27139 was constructed, and nine J1 phage-resistant mutants out of them were obtained. Cloning and sequencing analyses identified three independent genes that were disrupted by insertion of the transposon element: asnH, encoding asparagine synthetase, and dnaJ and dnaK, encoding the molecular chaperones DnaJ and DnaK, respectively. Using an in vivo mouse model of Listeria infection, only asnH mutant showed deficiency in their ability to enhance host innate immunity, and complementation of the mutation by introduction of the wild-type asnH in the mutant strain recovered the immuno-augmenting activity. AsnH protein exhibited asparagine synthetase activity when the lysozyme-treated cell wall extracts of L. casei ATCC 27139 was added as substrate. The asnH mutants lost the thick and rigid peptidoglycan features that are characteristic to the wild-type cells, indicating that AsnH of L. casei is involved in peptidoglycan biosynthesis. These results indicate that asnH is required for the construction of the peptidoglycan composition involved in the immune-activating capacity of L. casei ATCC 27139.

  19. Transposon mutagenesis of probiotic Lactobacillus casei identifies asnH, an asparagine synthetase gene involved in its immune-activating capacity.

    Directory of Open Access Journals (Sweden)

    Masahiro Ito

    Full Text Available Lactobacillus casei ATCC 27139 enhances host innate immunity, and the J1 phage-resistant mutants of this strain lose the activity. A transposon insertion mutant library of L. casei ATCC 27139 was constructed, and nine J1 phage-resistant mutants out of them were obtained. Cloning and sequencing analyses identified three independent genes that were disrupted by insertion of the transposon element: asnH, encoding asparagine synthetase, and dnaJ and dnaK, encoding the molecular chaperones DnaJ and DnaK, respectively. Using an in vivo mouse model of Listeria infection, only asnH mutant showed deficiency in their ability to enhance host innate immunity, and complementation of the mutation by introduction of the wild-type asnH in the mutant strain recovered the immuno-augmenting activity. AsnH protein exhibited asparagine synthetase activity when the lysozyme-treated cell wall extracts of L. casei ATCC 27139 was added as substrate. The asnH mutants lost the thick and rigid peptidoglycan features that are characteristic to the wild-type cells, indicating that AsnH of L. casei is involved in peptidoglycan biosynthesis. These results indicate that asnH is required for the construction of the peptidoglycan composition involved in the immune-activating capacity of L. casei ATCC 27139.

  20. Technique of nuclear reactors controls; Technique des controles des reacteurs nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Weill, J [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1953-12-15

    This report deal about 'Techniques of control of the nuclear reactors' in the goal to achieve the control of natural uranium reactors and especially the one of Saclay. This work is mainly about the measurement into nuclear parameters and go further in the measurement of thermodynamic variables,etc... putting in relief the new features required on behalf of the detectors because of their use in the thermal neutrons flux. In the domain of nuclear measurement, we indicate the realizations and the results obtained with thermal neutron detectors and for the measurement of ionizations currents. We also treat the technical problem of the start-up of a reactor and of the reactivity measurement. We give the necessary details for the comprehension of all essential diagrams and plans put on, in particular, for the reactor of Saclay. (author) [French] Nous avons aborde le probleme de la ''Technique du Controle des reacteurs nucleaires'' dans le but de realiser le controle du reacteur de Saclay. C'est ainsi que nous avons ete amene a etudier le probleme dans son ensemble, tel qu'il se pose pour tout reacteur a uranium naturel. Ce travail traite principalement du domaine des mesures a caractere nucleaire et s'etend dans le domaine des mesures thermodynamque de niveaux, etc... mettant en relief les caracteristiques nouvelles exigees de la part des detecteurs du fait de leur utilisation dans le flux de neutrons thermiques. Dans le domaine de mesures nucleaires, nous indiquons principalement les realisations et les resultats obtenus pour les detecteurs de neutrons thermiques et pour la mesure de courants d'ionisations. Nous traitons egalement du probleme technique du demarrage d'un reacteur et du probleme de la mesure de la reactivite. Nous donnons les details necessaires a la comrehension de tous les schemas et plans de cablages essentiels mis au point, en particulier, pour le reacteur de Saclay. (auteur)

  1. An absolute nuclear magnetic resonance magnetometer; Magnetometre absolu a resonance magnetique nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Salvi, A [Commisariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1961-10-15

    After an introduction in which the various work undertaken since the discovery of nuclear magnetic resonance is rapidly reviewed, the author describes briefly In the first chapter three types of NMR magnetometers, giving the advantages and disadvantages of each of them and deducing from this the design of the apparatus having the greatest number of qualities Chapter II is devoted to the crossed coil nuclear oscillator which operates continuously over a wide range (800 gamma). To avoid an error due to a carrying over the frequency, the measurement is carried out using bands of 1000 {gamma}. Chapter III deals with frequency measurements. The author describes an original arrangement which makes possible the frequency-field conversion with an accuracy of {+-} 5 x 10{sup -6}, and the differential measurement between two nuclear oscillators. The report finishes with a conclusion and a few recordings. (author) [French] Apres une introduction rappelant les divers travaux effectues en resonance magnetique nucleaire depuis sa mise en evidence, l'auteur decrit sommairement dans le premier chapitre trois types de magnetometre a R.M.N. enumerant les avantages et les inconvenients de chacun a partir desquels il projet, l'appareillage reunissant le maximum de qualites. Le chapitre II est consacre a l'oscillateur nucleaire a bobines croisees permettant un fonctionnement continu dons une large plage (800 gamma). Pour eviter une erreur due a l'entrainement de frequence, la mesure s'effectue par bandes de 1000 {gamma} chacune. Le chapitre III traite la mesure de frequence. L'auteur expose un montage original permettant la traduction frequence-champ avec une precision egale a {+-} 5.10{sup -6}, et la mesure differentielle entre deux oscillateurs nucleaires. Une conclusion et quelques enregistrements terminent ce travail. (auteur)

  2. Significant event of patient radiation protection in radiotherapy (criterion 2.1): declaration and rating on the ASN-SFRO scale - ASN guide nr 16 - Release of the 01/01/2010

    International Nuclear Information System (INIS)

    2010-01-01

    This document brings together all the tools for the management of a significant event in radiation protection concerning a patient in radiotherapy. It contains the declaration form, a model for the reporting of significant events, and the ASN-SFRO scale which allows the event to be rated. After a presentation of the regulatory context and references, of the scope of application, this guide addresses the declaration of a significant event: general principles, definition of the 2.1 criterion, examples, delays and modalities of declaration, addressees of a declaration. It addresses the reporting of a significant event: general principles, sending delays and modalities. It addresses the rating on the ASN-SFRO scale: general principles, scale, and rating process. The last part deals with public information

  3. Significant event of patient radiation protection in radiotherapy (criterion 2.1): declaration and rating on the ASN-SFRO scale - ASN guide no. 16 - Release of 17/07/2015

    International Nuclear Information System (INIS)

    2015-01-01

    This document is an update of the previous version from October 2010. It brings together all the tools for the management of a significant event in radiation protection concerning a patient in radiotherapy. It contains the declaration form, a model for the reporting of significant events, and the ASN-SFRO scale which allows the event to be rated. After a presentation of the regulatory context and references, of the scope of application, this guide addresses the declaration of a significant event: general principles, definition of the 2.1 criterion, examples, delays and modalities of declaration, addressees of a declaration. It addresses the reporting of a significant event: general principles, sending delays and modalities. It addresses the rating on the ASN-SFRO scale: general principles, scale, and rating process. The last part deals with public information

  4. Nuclear biological studies in France; Les etudes de biologie nucleaires en France

    Energy Technology Data Exchange (ETDEWEB)

    Coursaget, J. [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1961-07-01

    On the occasion of a colloquium on radiobiological research programmes, a number of documents dealing with French accomplishments and projects in this field were collected together. We felt that it would be useful to assemble these papers in one report; although they are brief and leave gaps to be filled in, they provide certain data, give an overall view of the situation, and can also suggest a rough plan for the general policy to adopt in the field of 'nuclear' biological research; i.e. research based on the nuclear tracer method or devoted to the action of ionising radiations. (author) [French] Un colloque sur les programmes de recherche en radiobiologie nous a donne l'occasion de reunir des documents sur les realisations et les projets francais dans ce domaine. Il nous a semble utile de reunir en un rapport l'ensemble de ces documents, qui, malgre leur brievete et malgre les lacunes qu'ils comportent, donnent un certain nombre d'informations, permettent une vue d'ensemble et peuvent dessiner aussi l'ebauche d'une politique coherente en matiere de recherches biologiques 'nucleaires', c'est-a-dire de recherches basees sur la methode des indicateurs nucleaires ou consacrees a l'action des rayonnements ionisants. (auteur)

  5. The formation of scientists and technicians at the 'Centre d'Etudes Nucleaires' at Saclay

    International Nuclear Information System (INIS)

    Debiesse, J.

    1958-01-01

    The considerable needs in research workers and scientists which are asked by the nuclear energy obliged the Commissariat a l'Energie atomique to deal with a particular effort to increase the quantitative and qualitative formation of scientists. Most various ways have been used. 1- A National Institute of Nuclear Sciences and Nuclear Techniques was created, by a joint decree of the Prime Minister and the Minister for National Education (june 18, 1957). This Institute of Higher Teaching (250 students) indulges in the following matters: atomic engineering, quantum mechanics, theory and technic of particle accelerators, special metallurgy, radiobiology, thermic and mechanics of fluids. 2- An associated centre of the 'Conservatoire National des Arts et Metiers' was created (200 students) for technical assistants, drawers, etc. 3- In contribution with both electronic industry and Ministry of Work, the Centre d'Etudes Nucleaires contributes to an accelerated formation of technical assistants into Professional Centres. Conclusion: Training of scientists and research workers is one of the most important activities of the Centre d'Etudes Nucleaires de Saclay. Without losing its technical efficiency, it has supplied and varied means adapted to the various purposes that we shall reach. (author) [fr

  6. Nuclear biological studies in France; Les etudes de biologie nucleaires en France

    Energy Technology Data Exchange (ETDEWEB)

    Coursaget, J [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1961-07-01

    On the occasion of a colloquium on radiobiological research programmes, a number of documents dealing with French accomplishments and projects in this field were collected together. We felt that it would be useful to assemble these papers in one report; although they are brief and leave gaps to be filled in, they provide certain data, give an overall view of the situation, and can also suggest a rough plan for the general policy to adopt in the field of 'nuclear' biological research; i.e. research based on the nuclear tracer method or devoted to the action of ionising radiations. (author) [French] Un colloque sur les programmes de recherche en radiobiologie nous a donne l'occasion de reunir des documents sur les realisations et les projets francais dans ce domaine. Il nous a semble utile de reunir en un rapport l'ensemble de ces documents, qui, malgre leur brievete et malgre les lacunes qu'ils comportent, donnent un certain nombre d'informations, permettent une vue d'ensemble et peuvent dessiner aussi l'ebauche d'une politique coherente en matiere de recherches biologiques 'nucleaires', c'est-a-dire de recherches basees sur la methode des indicateurs nucleaires ou consacrees a l'action des rayonnements ionisants. (auteur)

  7. Associative memories in nuclear physics; Les memoires associatives en physique nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Blanca, E; Carriere, A [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1967-07-01

    Experiments in nuclear physics involve the use of large size 'memories'. After showing the difficulties arising from the use of such memories, the authors give the principles of the various programming methods which make it possible to operate the memories associatively thus benefiting from a reduction in size and better operational conditions. They attempt to estimate the shape and dimensions of an associative memory with cable connections which could be designed specially for nuclear research, contrary to those actually in service. (authors) [French] Les experiences de physique nucleaire necessitent l'emploi de 'memoires' de grandes dimensions. Apres avoir montre les inconvenients que presente l'utilisation de telles memoires, les auteurs exposent les principes des diverses methodes de programmation qui permettent d'assurer un fonctionnement des memoires sur le mode associatif donc une reduction de leurs dimensions et un meilleur usage. Ils tentent d'evaluer le format d'une memoire associative cablee qui, contrairement a celles qui existent actuellement, serait prevue specialement pour l'experimentation nucleaire. (auteurs)

  8. Analytic index for nuclear physicians uses; Repertoire analytique a l'usage des physiciens nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Ballini, R.; Barloutaud, R.; Bernas, R.; Bretonneau, P.; Chaminade, R.; Cohen, R.; Conjeaud, M.; Cotton, E.; Faraggi, H.; Grjebine, T.; Joffre, H.; Laboulaye, H. de; Lesueur, C.; Leveque, A.; Moreau, J.; Naggiar, V.; Papineau, L.; Prugne, P.; Schuhl, C.; Studinowski, FJ.; Netter, F.; Raievski, V.; Valladas, G. [Commissariat a l' Energie Atomique, Lab. du Fort de Chatillon, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires; Marty, N.; Renard, G. [College de France, Lab. de Chimie Nucleaire (France)

    The problem of the documentation in nuclear physics becomes constantly more complex. Every week brings its share of new publications, always more numerous and more varied. To remedy to this facts that we tried, in the service of Nuclear Physics of the CEA, to give to the documentation a character of a collective and systematized work. The present report covers the literature appeared between first January 1950 and first July 1951. (Volume 1: CEA report number 120; Volume 2: CEA report number 184). (M.B.) [French] Le probleme de la documentation en physique nucleaire devient sans cesse plus complexe. Chaque semaine apporte son lot de publications, toujours plus nombreuses et plus diversifiees. C'est pour essayer de porter remede a cet etat de choses que nous avons essaye, au service de Physique Nucleaire du C.E.A., de donner a la documentation le caractere d'un travail collectif systematise. Le present rapport couvre la litterature parue entre le premier Janvier 1950 et le premier Juillet 1951. (Tome 1: Rapport CEA numero 120; Tome 2: Rapport CEA numero 184). (M.B.)

  9. Asn792 participates in the hydrogen bond network around the K+-binding pocket of gastric H,K-ATPase.

    NARCIS (Netherlands)

    Swarts, H.G.P.; Koenderink, J.B.; Willems, P.H.G.M.; Krieger, E.; Pont, J.J.H.H.M. de

    2005-01-01

    Asn792 present in M5 of gastric H,K-ATPase is highly conserved within the P-type ATPase family. A direct role in K+ binding was postulated for Na,K-ATPase but was not found in a recent model for gastric H,K-ATPase (Koenderink, J. B., Swarts, H. G. P., Willems, P. H. G. M., Krieger, E., and De Pont,

  10. The ASN and nuclear facilities: towards a strengthening of safety margins

    International Nuclear Information System (INIS)

    Anon.

    2012-01-01

    The new measures taken by the French Nuclear Safety Authority (ASN) as a consequence of the complementary safety assessments performed recently on nuclear facilities are reviewed in this article. The main measures are the following. Concerning EDF: -) the setting of a hard core of measures in order to assure a few safety-vital functions in any case, for instance one of this measures is to bunker some of the emergency diesel sets; -) the setting of a rapid intervention force able to provide any damaged nuclear plant with extra means in cooling and power in a very short time; -) a better training of the staff in case of severe accident. Concerning AREVA: the setting of robust means to assure the water supply of the fuel pool at La Hague plant and the setting of efficient means to mitigate the consequences of a leak of ClF 3 , HF, UF 6 in the premises of Eurodif, Socatri, TU5, GB 2 and Comurhex. Concerning CEA: -) the removal of fissile materials from the Masurca facility, -) the setting up of improved means concerning flood and sodium fires at the Phenix reactor, -) the setting up of improved means concerning the loss of coolant at the Osiris reactor, -) the setting up of improved means in case of flood, earthquake and loss of coolant at the Jules Horowitz reactor. (A.C.)

  11. ASN: regional day of information and exchange on transport of radioactive materials - 4 February 2010

    International Nuclear Information System (INIS)

    2010-01-01

    This document gathers Power Point presentations made during a meeting on the transport of radioactive materials. The contributions addressed the following topics: results of a survey based on questionnaires sent to actors of this sector, regulatory framework and radioprotection plan, case of parcels not submitted to the authority concerned, declaration of transport interesting or significant events, ASN inspections, the transport of radioactive products by the IBt Bebig company in France, the activities of the Institut de Soudure Industrie (industry welding institute), the activities of the ISO Life company specialized in health product transportation, the activities of the Securidis company (a consulting company for activities related to hazardous materials transportation, and notably radioactive materials), the activities a the ACE Environnement company (specialized in building diagnosis), the point of view of an academic research unit on radioactive material transportation, the experience of the hospital sector in radioactive source transportation, the experience of the Advanced Accelerator Applications company in radioactive material transportation, and a discussion on regulation application

  12. Evaluation guideline for the study of the radiological impact of based nuclear installations (INB) presented in support of releases authorization demands; Guide d'examen pour l'etude de l'impact radiologique d'une installation nucleaire de base (INB) fournie a l'appui des demandes d'autorisation de rejets

    Energy Technology Data Exchange (ETDEWEB)

    Chartier, M; Despres, A; Supervil, S; Conte, D; Hubert, P; Oudiz, A; Champion, D

    2002-10-01

    In the case of a license demand for the effluents release and water taking for a nuclear installation, the operating must realize a study of the nuclear effluents radiological impact on the environment and the public health. In this context, the study presents technical and methodological specifications which led the Direction of the Nuclear Installations Safety (DSIN) and the General Direction of the Health (DGS) to ask the IPSN the elaboration of a guideline to help these studies evaluation. The guideline presents the regulatory context, the description of the installations, the treatment and the control processes, the rules of management, the description of the environment, the estimation of the radiological impacts and the environment control system definition. (A.L.B.)

  13. Evaluation guideline for the study of the radiological impact of based nuclear installations (INB) presented in support of releases authorization demands; Guide d'examen pour l'etude de l'impact radiologique d'une installation nucleaire de base (INB) fournie a l'appui des demandes d'autorisation de rejets

    Energy Technology Data Exchange (ETDEWEB)

    Chartier, M.; Despres, A.; Supervil, S.; Conte, D.; Hubert, P.; Oudiz, A.; Champion, D

    2002-10-01

    In the case of a license demand for the effluents release and water taking for a nuclear installation, the operating must realize a study of the nuclear effluents radiological impact on the environment and the public health. In this context, the study presents technical and methodological specifications which led the Direction of the Nuclear Installations Safety (DSIN) and the General Direction of the Health (DGS) to ask the IPSN the elaboration of a guideline to help these studies evaluation. The guideline presents the regulatory context, the description of the installations, the treatment and the control processes, the rules of management, the description of the environment, the estimation of the radiological impacts and the environment control system definition. (A.L.B.)

  14. Senate report n. 327 law project authorizing the approbation of international agreements on the civil liability in the domain of the nuclear energy; Senat rapport n. 327 projet de loi autorisant l'approbation d'accords internationaux sur la responsabilite civile dans le domaine de l'energie nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    The objective of this law project is to approve two protocols aiming to modify the OECD convention on the civil liability in the nuclear energy domain. After a short presentation of the international regime of civil liability in the nuclear domain with the Paris and Vienna conventions, the author analyzes the main improvements offered by the two protocols of February 2004 facing the french legislation. (A.L.B.)

  15. Project of decree relative to the licensing and statement system of nuclear activities and to their control and bearing various modifications of the public health code and working code; Projet de decret relatif au regime d'autorisation et de declaration des activites nucleaires et a leur controle et portant diverses modifications du code de la sante publique et du code du travail

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    This decree concerns the control of high level sealed radioactive sources and orphan sources. It has for objective to introduce administrative simplification, especially the radiation sources licensing and statement system, to reinforce the control measures planed by the public health code and by the employment code, to bring precision and complements in the editing of several already existing arrangements. (N.C.)

  16. From crisis exercises to the management of emergency situations...The experience of a local branch of ASN

    International Nuclear Information System (INIS)

    Deproit, L.; Vieuble, J.

    2016-01-01

    The local branch of the ASN (Nuclear Safety Authority) in the Marseille region controls the nuclear activities in 13 departments and Corsica. The preparation of the crisis management relies on the involvement of various actors: representatives of public bodies, nuclear plant operators, the ASN and its technical assistance (IRSN - Institute for Radiation-protection and Nuclear Safety). Crisis exercises are necessary to check the right coordination of all the actors. The feedback of real situations involving incidents are also important because it allows all the actors to better know each other, the case of the accident of the Centraco facility is detailed as well as the robbery of a truck carrying a radioactive source or the discovery of a collection of radioactive sources in a private home. In each case the lesson learned by the local branch of ASN is to communicate quickly with local authorities in order to get the best technical response to the situation and to give authorities all the information necessary for an efficient information of the public. (A.C.)

  17. The formation of scientists and technicians at the 'Centre d'Etudes Nucleaires' at Saclay; Formation des scientifiques et des techniciens au Centre d'Etudes Nucleaires de Saclay

    Energy Technology Data Exchange (ETDEWEB)

    Debiesse, J [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    The considerable needs in research workers and scientists which are asked by the nuclear energy obliged the Commissariat a l'Energie atomique to deal with a particular effort to increase the quantitative and qualitative formation of scientists. Most various ways have been used. 1- A National Institute of Nuclear Sciences and Nuclear Techniques was created, by a joint decree of the Prime Minister and the Minister for National Education (june 18, 1957). This Institute of Higher Teaching (250 students) indulges in the following matters: atomic engineering, quantum mechanics, theory and technic of particle accelerators, special metallurgy, radiobiology, thermic and mechanics of fluids. 2- An associated centre of the 'Conservatoire National des Arts et Metiers' waeated (200 students) for technical assistants, drawers, etc. 3- In contribution with both electronic industry and Ministry of Work, the Centre d'Etudes Nucleaires contributes to an accelerated formation of technical assistants into Professional Centres. Conclusion: Training of scientists and research workers is one of the most important activities of the Centre d'Etudes Nucleaires de Saclay. Without losing its technical efficiency, it has supplied and varied means adapted to the various purposes that we shall reach. (author)Fren. [French] Les besoins considerables actuels et previsibles en chercheurs et scientifiques necessites par l'avevement de l'energie nucleaire imposaient au Commissariat a I'Energie atomique un effort particulier pour augmenter la formation quantitative et qualitative des scientifiques. Les moyens les plus divers ont ete mis en oeuvre: 1- Creation de l'Institut National des Sciences et Techniques Nucleaires par decret de la Presidence du Conseil et de l'Education Nationale en date du 18.6.57. Cet Institut d'Enseignement Superieur (250 etudiants) donne des cours en: genie atomique, mecanique quantique, theorie et technique des Accelerateurs de particules, metallurgie speciale, radiobiologie

  18. N-linked glycosylation at Asn152 on CD147 affects protein folding and stability: promoting tumour metastasis in hepatocellular carcinoma.

    Science.gov (United States)

    Li, Jiang-Hua; Huang, Wan; Lin, Peng; Wu, Bo; Fu, Zhi-Guang; Shen, Hao-Miao; Jing, Lin; Liu, Zhen-Yu; Zhou, Yang; Meng, Yao; Xu, Bao-Qing; Chen, Zhi-Nan; Jiang, Jian-Li

    2016-11-21

    Cluster of differentiation 147 (CD147), also known as extracellular matrix metalloproteinase inducer, is a transmembrane glycoprotein that mediates oncogenic processes partly through N-glycosylation modifications. N-glycosylation has been demonstrated to be instrumental for the regulation of CD147 function during malignant transformation. However, the role that site-specific glycosylation of CD147 plays in its defective function in hepatocellular carcinomacells needs to be determined. Here, we demonstrate that the modification of N-glycosylation at Asn152 on CD147 strongly promotes hepatocellular carcinoma (HCC) invasion and migration. After the removal of N-glycans at Asn152, CD147 was more susceptible to degradation by ER-localized ubiquitin ligase-mediated endoplasmic reticulum-associated degradation (ERAD). Furthermore, N-linked glycans at Asn152 were required for CD147 to acquire and maintain proper folding in the ER. Moreover, N-linked glycans at Asn152 functioned as a recognition motif that was directly mediated by the CNX quality control system. Two phases in the retention-based ER chaperones system drove ER-localized CD147 trafficking to degradation. Deletion of N-linked glycosylation at Asn152 on CD147 significantly suppressed in situ tumour metastasis. These data could potentially shed light on the molecular regulation of CD147 through glycosylation and provide a valuable means of developing drugs that target N-glycans at Asn152 on CD147.

  19. Genetic polymorphisms of xeroderma pigmentosum group D gene Asp312Asn and Lys751Gln and susceptibility to prostate cancer: a systematic review and meta-analysis.

    Science.gov (United States)

    Ma, Qingtong; Qi, Can; Tie, Chong; Guo, Zhanjun

    2013-11-10

    Many studies have reported the role of xeroderma pigmentosum group D (XPD) with prostate cancer risk, but the results remained controversial. To derive a more precise estimation of the relationship, a meta-analysis was performed. Odds ratios (ORs) with 95% confidence intervals (CIs) were estimated to assess the association between XPD Asp312Asn and Lys751Gln polymorphisms and prostate cancer risk. A total of 8 studies including 2620 cases and 3225 controls described Asp312Asn genotypes, among which 10 articles involving 3230 cases and 3582 controls described Lys751Gln genotypes and were also involved in this meta-analysis. When all the eligible studies were pooled into this meta-analysis, a significant association between prostate cancer risk and XPD Asp312Asn polymorphism was found. For Asp312Asn polymorphism, in the stratified analysis by ethnicity and source of controls, prostate cancer risk was observed in co-dominant, dominant and recessive models, while no evidence of any associations of XPD Lys751Gln polymorphism with prostate cancer was found in the overall or subgroup analyses. Our meta-analysis supports that the XPD Asp312Asn polymorphism contributed to the risk of prostate cancer from currently available evidence. However, a study with a larger sample size is needed to further evaluate gene-environment interaction on XPD Asp312Asn and Lys751Gln polymorphisms and prostate cancer risk. © 2013.

  20. Effects of mutation of Asn694 in Aspergillus niger α-glucosidase on hydrolysis and transglucosylation.

    Science.gov (United States)

    Ma, Min; Okuyama, Masayuki; Sato, Megumi; Tagami, Takayoshi; Klahan, Patcharapa; Kumagai, Yuya; Mori, Haruhide; Kimura, Atsuo

    2017-08-01

    Aspergillus niger α-glucosidase (ANG), a member of glycoside hydrolase family 31, catalyzes hydrolysis of α-glucosidic linkages at the non-reducing end. In the presence of high concentrations of maltose, the enzyme also catalyzes the formation of α-(1→6)-glucosyl products by transglucosylation and it is used for production of the industrially useful panose and isomaltooligosaccharides. The initial transglucosylation by wild-type ANG in the presence of 100 mM maltose [Glc(α1-4)Glc] yields both α-(1→6)- and α-(1→4)-glucosidic linkages, the latter constituting ~25% of the total transfer reaction product. The maltotriose [Glc(α1-4)Glc(α1-4)Glc], α-(1→4)-glucosyl product disappears quickly, whereas the α-(1→6)-glucosyl products panose [Glc(α1-6)Glc(α1-4)Glc], isomaltose [Glc(α1-6)Glc], and isomaltotriose [Glc(α1-6)Glc(α1-6)Glc] accumulate. To modify the transglucosylation properties of ANG, residue Asn694, which was predicted to be involved in formation of the plus subsites of ANG, was replaced with Ala, Leu, Phe, and Trp. Except for N694A, the mutations enhanced the initial velocity of the α-(1→4)-transfer reaction to produce maltotriose, which was then degraded at a rate similar to that by wild-type ANG. With increasing reaction time, N694F and N694W mutations led to the accumulation of larger amounts of isomaltose and isomaltotriose than achieved with the wild-type enzyme. In the final stage of the reaction, the major product was panose (N694A and N694L) or isomaltose (N694F and N694W).

  1. Material movement of medium surrounding an underground nuclear explosion; Mouvement materiel du milieu environnant une explosion nucleaire souterraine

    Energy Technology Data Exchange (ETDEWEB)

    Guerrini, C; Garnier, J L [Commissariat a l' Energie Atomique, Bruyeres-le-Chatel (France). Centre d' Etudes

    1969-07-01

    The results of measurements of the mechanical effects in the, intermediate zone around underground nuclear explosions in Sahara granite are presented. After a description of the main characteristics of the equipment used, the laws drawn up using experimental results for the acceleration, the velocity, and the material displacement are presented. These laws are compared to those published in other countries for nuclear tests in granite, in tuff and in alluvial deposits. (authors) [French] Les resultats de mesures d'effets mecaniques en zone intermediaire autour d'essais nucleaires souterrains dans le granite du Sahara sont exposes. Apres avoir decrit, dans leurs grandes lignes, les materiels utilises, on presente les lois etablies avec les resultats experimentaux pour l'acceleration, la vitesse et le deplacement materiel. Ces lois sont comparees a celles publiees a l'etranger pour des essais nucleaires dans le granite, le tuf et les alluvions. (auteur)

  2. Contribution to the study of several chemical hazards in the Centre d'Etudes Nucleaires of Fontenay-aux-Roses; Contribution a l'etude de quelques nuisances chimiques au centre d'etudes nucleaires de Fontenay-aux-Roses

    Energy Technology Data Exchange (ETDEWEB)

    Megemont, C; Grau, C [Commissariat a l' Energie Atomique, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

    1968-10-01

    From the checking of 2750 index cards of hazards, the study relates the distribution of the chemical hazards in the Centre d'Etudes Nucleaires of Fontenay-aux-Roses. Those concerning the greatest number of agents in the Centre are classified according to the categories corresponding to the different conditions of working. Thus, the most important are put forward. Then, the authors rapidly make a review of hazards which may have some special interest because they appear more specific of the nuclear energy or because they are the most frequently noted on the index cards of hazards. The case of the tributylphosphate is studied more precisely. (authors) [French] A partir de l'examen de 2750 fiches de nuisances, l'etude porte sur la repartition des nuisances chimiques au Centre d'Etudes Nucleaires de Fontenay-aux-Roses. Celles qui concernent le plus grand nombre d'agents du Centre sont classees selon les categories correspondant aux differentes conditions de travail. Les plus importantes d'entre elles sont ainsi mises en evidence. | Les auteurs passent ensuite en revue, rapidement, les nuisances qui peuvent presenter un interet particulier soit parce qu'elles semblent plus specifiques de l'Energie Nucleaire, soit parce qu'on les rencontre le plus frequemment sur les fiches de nuisances. Le cas du tributylphosphate est envisage de facon plus detaillee. (auteurs)

  3. Evolution of nuclear chemical industry in France; Evolution de l'industrie chimique nucleaire en France

    Energy Technology Data Exchange (ETDEWEB)

    Fould, M H [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1959-07-01

    'impulsion du CEA, mais aussi de maitres d'oeuvres tels qu'Electricite de France et la Marine Marchande, l'effort nucleaire fran is atteint pour les annees 1957-1961, environ 600 milliards de francs: plus de la moitie de cette somme sera depensee par l'industrie chimique en recherches, installations pilotes, constructions d'usines et livraisons. Faire bien, vite et rentable sont les buts recherches. Ces objectifs sont atteints grace a une collaboration intime des grands services de l'etat et de l'industrie privee. Ce gros effort s'exerce principalement dans les voies suivantes: - Un traitement chimique pousse de tonnages croissants des minerais de l'Union fran ise, visant a produire un uranium pur, abondant et bon marche. - Une preparation soigneuse de combustibles nucleaires economiques et parfaitement adaptes aux divers types de reacteurs en fonctionnement ou en construction. - Un retraitement des combustibles irradies pour en extraire le plutonium de facon complete ainsi que l'uranium et certains produits de fission. - Une fabrication industrielle des materiaux nucleairement purs ou resistants a la corrosion exiges par la technologie des reacteurs producteurs d'energie et de recherches. - La fourniture aux multiples utilisateurs etrangers et fran is d'isotopes et de traceurs radioactifs reclames par la medecine, l'industrie et l'agriculture en nombre toujours croissant. - Un traitement chimique meticuleux des effluents gazeux ou liquides dans des stations au controle rigoureux afin de rendre les reacteurs et leurs annexes parfaitement surs d'emploi. Cet expose aura montre l'ampleur de l'effort deploye par une industrie chimique nucleaire jeune, dynamique et en plein essor. Ayant assure ses techniques, realise de nombreuses installations, elle est largement en etat de faire face au programme atomique fran is. En outre, elle est capable et desireuse d'etre associee aux developpements de l'industrie atomique etrangere notamment dans te cadre de l'Euratom et d

  4. Direct interaction in nuclear reactions: a theory; L'interaction directe dans les reactions nucleaires: theorie

    Energy Technology Data Exchange (ETDEWEB)

    Dominicis, C.T. de [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1959-07-01

    General treatment of the foundations of direct interaction in nuclear reactions; representation of the instantaneous elastic scattering amplitude by the scattering amplitude due to a complex potential; expansion of the instantaneous inelastic scattering amplitude and discussion of the 1. Bohr approximation (distorted waves) contribution to individual and collective states of excitation. (author) [French] Expose general sur les fondements de l'interaction directe dans les reactions nucleaires; representation de l'amplitude de diffusion instantanee elastique par celle due a un potentiel complexe; developpement de l'amplitude de diffusion instantanee inelastique et discussion de la contribution de la premiere approximation de Bohr (sur des distendues) a l'excitation d'etats individuels et collectifs. (auteur)

  5. The 1989 annual report of the Institut de Physique Nucleaire-Orsay

    International Nuclear Information System (INIS)

    1989-01-01

    The activity report of the Institut de Physique Nucleaire (Orsay-France) from 1 Sep 1988 to 1 Aug 1989 is presented. Theoretical and experimental investigations were carried out in the following fields: light and medium exotic nuclei, on line spectroscopy, discrete high spin states, new radioactivities, thermal fission, detection systems, giant resonances, high excitation energy structure, reaction mechanisms at energies below 10 MeV/u and at 200 MeV/u and their evolution between 10 and 100 MeV/u, meson production, transfer reactions, spin modes in nuclei, dibaryonic resonances, inelastic scattering of polarized protons. Research programs in the field of radiochemistry and relating to inter-disciplinary fields are included. The activities involving teaching, the lists of publications conferences, seminars and theses are presented [fr

  6. French research in the field of nuclear agronomy; Les recherches francaises en agronomie nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Guerin De Montgareuil, P. [Commissariat a l' Energie Atomique, Cadarache (France). Centre d' Etudes Nucleaires

    1964-07-01

    , industrial firms, university laboratories scientific institutes. The role of the Commissariat a l'Energie Atomique is defined: on the one hand it supplies information and support, and on the other hand it takes charge of specifically nuclear aspects of the work. Its part in the field has recently found expression in the creation, within the Biology Department, of a Radio-agronomy Section; its objective are described,, as well as the, means placed att its disposal at the Centre d'etudes Nucleaires, Cadarache. (author) [French] On propose un bilan des travaux les plus significatifs effectues en France depuis la deuxieme conference internationale en matiere d'agronomie nucleaire et qui vont d'une recherche apparemment desinteressee a l'application la plus directe. Une telle differenciation recouvre de moins en moins, au fur et a mesure de l'evolution des programmes, la distinction qui est faite dans l'expose entre l'action biologique des rayonnements et les autres emplois des techniques nucleaires. C'est ainsi que les recherches do radiogenetique agricole sont poursuivies dans deux directions: d'un point de vue theorique et methodologique avec l'etude comparative de l'action des divers types de rayonnements, l'influence du debit de dose et de la temperature, l'action des agents mutagenes chimiques, la production de chimeres sous irradiation gamma; et d'autre part, sous un aspect pratique aboutissant a la creation de varietes nouvelles plus resistantes ou plus precoces (riz, mil, arachide). Les problemes de destruction des insectes (eradication) et de conservation des denrees sous irradiation se trouvent egalement abordes par des voies et avec des objectifs tres divers. A la demarche globale representee par une irradiation pure et simple (grains humides, pommes de terre...) sont parfois associees des etudes souvent originales, d'ordre biochimique ou microbiologique (par exemple: alteration de l

  7. French research in the field of nuclear agronomy; Les recherches francaises en agronomie nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Guerin De Montgareuil, P [Commissariat a l' Energie Atomique, Cadarache (France). Centre d' Etudes Nucleaires

    1964-07-01

    , industrial firms, university laboratories scientific institutes. The role of the Commissariat a l'Energie Atomique is defined: on the one hand it supplies information and support, and on the other hand it takes charge of specifically nuclear aspects of the work. Its part in the field has recently found expression in the creation, within the Biology Department, of a Radio-agronomy Section; its objective are described,, as well as the, means placed att its disposal at the Centre d'etudes Nucleaires, Cadarache. (author) [French] On propose un bilan des travaux les plus significatifs effectues en France depuis la deuxieme conference internationale en matiere d'agronomie nucleaire et qui vont d'une recherche apparemment desinteressee a l'application la plus directe. Une telle differenciation recouvre de moins en moins, au fur et a mesure de l'evolution des programmes, la distinction qui est faite dans l'expose entre l'action biologique des rayonnements et les autres emplois des techniques nucleaires. C'est ainsi que les recherches do radiogenetique agricole sont poursuivies dans deux directions: d'un point de vue theorique et methodologique avec l'etude comparative de l'action des divers types de rayonnements, l'influence du debit de dose et de la temperature, l'action des agents mutagenes chimiques, la production de chimeres sous irradiation gamma; et d'autre part, sous un aspect pratique aboutissant a la creation de varietes nouvelles plus resistantes ou plus precoces (riz, mil, arachide). Les problemes de destruction des insectes (eradication) et de conservation des denrees sous irradiation se trouvent egalement abordes par des voies et avec des objectifs tres divers. A la demarche globale representee par une irradiation pure et simple (grains humides, pommes de terre...) sont parfois associees des etudes souvent originales, d'ordre biochimique ou microbiologique (par exemple: alteration de l'amidon, metabolisme glucidique des tubercules irradies, radioresistance des levures

  8. Ser95, Asn97, and Thr78 are important for the catalytic function of porcine NADP-dependent isocitrate dehydrogenase

    OpenAIRE

    Kim, Tae-Kang; Colman, Roberta F.

    2005-01-01

    The mammalian mitochondrial NADP-dependent isocitrate dehydrogenase is a citric acid cycle enzyme and an important contributor to cellular defense against oxidative stress. The Mn2+-isocitrate complex of the porcine enzyme was recently crystallized; its structure indicates that Ser95, Asn97, and Thr78 are within hydrogen-bonding distance of the γ-carboxylate of enzyme-bound isocitrate. We used site-directed mutagenesis to replace each of these residues by Ala and Asp. The wild-type and mutant...

  9. Cell Cycle-Dependent Recruitment of Polycomb Proteins to the ASNS Promoter Counteracts C/ebp-Mediated Transcriptional Activation in Bombyx mori

    Science.gov (United States)

    Li, Zhiqing; Cheng, Daojun; Mon, Hiroaki; Zhu, Li; Xu, Jian; Tatsuke, Tsuneyuki; Lee, Jae Man; Xia, Qingyou; Kusakabe, Takahiro

    2013-01-01

    Epigenetic modifiers and transcription factors contribute to developmentally programmed gene expression. Here, we establish a functional link between epigenetic regulation by Polycomb group (PcG) proteins and transcriptional regulation by C/ebp that orchestrates the correct expression of Bombyx mori asparagine synthetase (BmASNS), a gene involved in the biosynthesis of asparagine. We show that the cis-regulatory elements of YY1-binding motifs and the CpG island present on the BmASNS promoter are required for the recruitment of PcG proteins and the subsequent deposition of the epigenetic repression mark H3K27me3. RNAi-mediated knockdown of PcG genes leads to derepression of the BmASNS gene via the recruitment of activators, including BmC/ebp, to the promoter. Intriguingly, we find that PcG proteins and BmC/ebp can dynamically modulate the transcriptional output of the BmASNS target in a cell cycle-dependent manner. It will be essential to suppress BmASNS expression by PcG proteins at the G2/M phase of the cell cycle in the presence of BmC/ebp activator. Thus, our results provide a novel insight into the molecular mechanism underlying the recruitment and regulation of the PcG system at a discrete gene locus in Bombyx mori. PMID:23382816

  10. Mechanics and electronics as auxiliary techniques in nuclear research and exploitation; Mecanique et electronique auxiliaires de la recherche et de l'exploitation nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Weill, J. [Commissariat a l' energie atomique et aux energies alternatives - CEA, Centre d' Etudes nucleaires de Saclay, Departement Electronique, Groupe Controle des Reacteurs (France)

    1959-07-01

    Electronics and mechanics form the basic techniques used in the field of measurement and control in nuclear physics experiments, and in nuclear machine installations. The delegate describes some instruments typical of the use of these techniques in the fields of calculation, detection, amplification and nuclear Installations. Reprint of a paper published in 'Bulletin S.F.M.' n. 25 (3. quarter 1957) [French] L'electronique et la mecanique constituent les techniques de base utilisees clans le domaine des mesures et du controle effectues dans les experiences de physique nucleaire et dans les installations des engins nucleaires. Le Conferencier decrit plusieurs appareils caracteristiques de l'emploi de ces techniques dans les domaines du calcul, des detecteurs, de l'amplification et des lnstallations nucleaires. Reproduction d'un article publie dans le 'Bulletin S.F.M.' n. 25 (3e trimestre 1957)

  11. Annual report ''nuclear safety in France''; Le rapport annuel ''la surete nucleaire en France''

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    This document is the 2001 annual report of the French authority of nuclear safety (ASN). It summarizes the highlights of the year 2000 and details the following aspects: the nuclear safety in France, the organization of the control of nuclear safety, the regulation relative to basic nuclear facilities, the control of facilities, the information of the public, the international relations, the organisation of emergencies, the radiation protection, the transport of radioactive materials, the radioactive wastes, the PWR reactors, the experimental reactors and other laboratories and facilities, the nuclear fuel cycle facilities, and the shutdown and dismantling of nuclear facilities. (J.S.)

  12. The nuclear safety authority (ASN) presents its report on the status of nuclear safety and radiation protection in France in 2010

    International Nuclear Information System (INIS)

    2011-01-01

    After a presentation of the French nuclear safety authority (ASN) and of some events which occurred in 2010, this report present the actions performed by the ASN in different fields: nuclear activities (ionizing radiations and risks for health and for the environment), principles and actors of control of nuclear safety, radiation protection and environment protection, regulation, control of nuclear activities and of exposures to ionizing radiations, emergency situations, public information and transparency, international relationship. It proposes a regional overview of nuclear safety and radiation protection in France. It addresses the activities controlled by the ASN: medical and non medical usages of ionizing radiations, transportation of radioactive materials, electronuclear power stations, installations involved in the nuclear fuel cycle, research nuclear installations and other nuclear installations, safety in basic nuclear installation dismantling, radioactive wastes and polluted sites

  13. Characterization of deamidation at Asn138 in L-chain of recombinant humanized Fab expressed from Pichia pastoris.

    Science.gov (United States)

    Ohkuri, Takatoshi; Murase, Eri; Sun, Shu-Lan; Sugitani, Jun; Ueda, Tadashi

    2013-10-01

    A method was previously established for evaluating Asn deamidation by matrix-assisted laser desorption/ionization time of flight-mass spectrometry using endoproteinase Asp-N. In this study, we demonstrated that this method could be applied to the identification of the deamidation site of the humanized fragment antigen-binding (Fab). First, a system for expressing humanized Fab from methylotrophic yeast Pichia pastoris was constructed, resulting in the preparation of ∼30 mg of the purified humanized Fab from 1 l culture. Analysis of the L-chain derived from recombinant humanized Fab that was heated at pH 7 and 100°C for 1 h showed the deamidation at Asn138 in the constant region. Then, we prepared L-N138D Fab and L-N138A Fab and examined their properties. The circular dichroism (CD) spectrum of the L-N138D Fab was partially different from that of the wild-type Fab. The measurement of the thermostability showed that L-N138D caused a significant decrease in the thermostability of Fab. On the other hand, the CD spectrum and thermostability of L-N138A Fab showed the same behaviour as the wild-type Fab. Thus, it was suggested that the introduction of a negative charge at position 138 in the L-chain by the deamidation significantly affected the stability of humanized Fab.

  14. Preventing E-cadherin aberrant N-glycosylation at Asn-554 improves its critical function in gastric cancer

    Science.gov (United States)

    Carvalho, S; Catarino, TA; Dias, AM; Kato, M; Almeida, A; Hessling, B; Figueiredo, J; Gärtner, F; Sanches, JM; Ruppert, T; Miyoshi, E; Pierce, M; Carneiro, F; Kolarich, D; Seruca, R; Yamaguchi, Y; Taniguchi, N; Reis, CA; Pinho, SS

    2016-01-01

    E-cadherin is a central molecule in the process of gastric carcinogenesis and its posttranslational modifications by N-glycosylation have been described to induce a deleterious effect on cell adhesion associated with tumor cell invasion. However, the role that site-specific glycosylation of E-cadherin has in its defective function in gastric cancer cells needs to be determined. Using transgenic mice models and human clinical samples, we demonstrated that N-acetylglucosaminyltransferase V (GnT-V)-mediated glycosylation causes an abnormal pattern of E-cadherin expression in the gastric mucosa. In vitro models further indicated that, among the four potential N-glycosylation sites of E-cadherin, Asn-554 is the key site that is selectively modified with β1,6 GlcNAc-branched N-glycans catalyzed by GnT-V. This aberrant glycan modification on this specific asparagine site of E-cadherin was demonstrated to affect its critical functions in gastric cancer cells by affecting E-cadherin cellular localization, cis-dimer formation, molecular assembly and stability of the adherens junctions and cell–cell aggregation, which was further observed in human gastric carcinomas. Interestingly, manipulating this site-specific glycosylation, by preventing Asn-554 from receiving the deleterious branched structures, either by a mutation or by silencing GnT-V, resulted in a protective effect on E-cadherin, precluding its functional dysregulation and contributing to tumor suppression. PMID:26189796

  15. Characterization of an Lrp/AsnC family regulator SCO3361, controlling actinorhodin production and morphological development in Streptomyces coelicolor.

    Science.gov (United States)

    Liu, Jing; Li, Jie; Dong, Hong; Chen, Yunfu; Wang, Yansheng; Wu, Hang; Li, Changrun; Weaver, David T; Zhang, Lixin; Zhang, Buchang

    2017-07-01

    Lrp/AsnC family regulators have been found in many bacteria as crucial regulators controlling diverse cellular processes. By genomic alignment, we found that SCO3361, an Lrp/AsnC family protein from Streptomyces coelicolor, shared the highest similarity to the SACE_Lrp from Saccharopolyspora erythraea. Deletion of SCO3361 led to dramatic reduction in actinorhodin (Act) production and delay in aerial mycelium formation and sporulation on solid media. Dissection of the mechanism underlying the function of SCO3361 in Act production revealed that it altered the transcription of the cluster-situated regulator gene actII-ORF4 by directly binding to its promoter. SCO3361 was an auto-regulator and simultaneously activated the transcription of its adjacent divergently transcribed gene SCO3362. SCO3361 affected aerial hyphae formation and sporulation of S. coelicolor by activating the expression of amfC, whiB, and ssgB. Phenylalanine and cysteine were identified as the effector molecules of SCO3361, with phenylalanine reducing the binding affinity, whereas cysteine increasing it. Moreover, interactional regulation between SCO3361 and SACE_Lrp was discovered for binding to each other's target gene promoter in this work. Our findings indicate that SCO3361 functions as a pleiotropic regulator controlling secondary metabolism and morphological development in S. coelicolor.

  16. Report by the ASN on the situation of nuclear safety and radiation protection in France in 2013

    International Nuclear Information System (INIS)

    Chevet, Pierre-Franck; Delmestre, Alain; Bardet, Marie-Christine; Covard, Fabienne; Javay, Olivier

    2014-01-01

    In its first chapters, this huge report presents the various actions undertaken by the ASN. It proposes a detailed overview of the issue of ionizing radiations and risks for health and for the environment in the field of nuclear activities, presents and comments the principles and actors of the control of nuclear safety and of radiation protection, presents the different elements of the legal framework, describes and comments the control of nuclear activities and of exposures to ionizing radiations. The next chapters address the actions controlled by the ASN: radiological and post-accidental radiological situations, present measures related to public information and transparency, overview of international relationships, regional overview of nuclear safety and radiation protection, medical use of ionizing radiations, industrial, research and veterinary uses and the issue of source safety, the issue of radioactive material transportation. Issues of nuclear safety and radiation protection are then discussed for electronuclear plants, for installations dedicated to the nuclear fuel cycle, for various research and industrial nuclear installations, for the dismantling of base nuclear installations, and for radioactive wastes and polluted sites and soils

  17. Bioremediation of acidic oily sludge-contaminated soil by the novel yeast strain Candida digboiensis TERI ASN6.

    Science.gov (United States)

    Sood, Nitu; Patle, Sonali; Lal, Banwari

    2010-03-01

    Primitive wax refining techniques had resulted in almost 50,000 tonnes of acidic oily sludge (pH 1-3) being accumulated inside the Digboi refinery premises in Assam state, northeast India. A novel yeast species Candida digboiensis TERI ASN6 was obtained that could degrade the acidic petroleum hydrocarbons at pH 3 under laboratory conditions. The aim of this study was to evaluate the degradation potential of this strain under laboratory and field conditions. The ability of TERI ASN6 to degrade the hydrocarbons found in the acidic oily sludge was established by gravimetry and gas chromatography-mass spectroscopy. Following this, a feasibility study was done, on site, to study various treatments for the remediation of the acidic sludge. Among the treatments, the application of C. digboiensis TERI ASN6 with nutrients showed the highest degradation of the acidic oily sludge. This treatment was then selected for the full-scale bioremediation study conducted on site, inside the refinery premises. The novel yeast strain TERI ASN6 could degrade 40 mg of eicosane in 50 ml of minimal salts medium in 10 days and 72% of heneicosane in 192 h at pH 3. The degradation of alkanes yielded monocarboxylic acid intermediates while the polycyclic aromatic hydrocarbon pyrene found in the acidic oily sludge yielded the oxygenated intermediate pyrenol. In the feasibility study, the application of TERI ASN6 with nutrients showed a reduction of solvent extractable total petroleum hydrocarbon (TPH) from 160 to 28.81 g kg(-1) soil as compared to a TPH reduction from 183.85 to 151.10 g kg(-1) soil in the untreated control in 135 days. The full-scale bioremediation study in a 3,280-m(2) area in the refinery showed a reduction of TPH from 184.06 to 7.96 g kg(-1) soil in 175 days. Degradation of petroleum hydrocarbons by microbes is a well-known phenomenon, but most microbes are unable to withstand the low pH conditions found in Digboi refinery. The strain C. digboiensis could efficiently degrade

  18. The role of a second-shell residue in modifying substrate and inhibitor interactions in the SHV beta-lactamase: a study of ambler position Asn276.

    Science.gov (United States)

    Drawz, Sarah M; Bethel, Christopher R; Hujer, Kristine M; Hurless, Kelly N; Distler, Anne M; Caselli, Emilia; Prati, Fabio; Bonomo, Robert A

    2009-06-02

    Inhibitor-resistant class A beta-lactamases of the TEM and SHV families that arise by single amino acid substitutions are a significant threat to the efficacy of beta-lactam/beta-lactamase inhibitor combinations. To better understand the basis of the inhibitor-resistant phenotype in SHV, we performed mutagenesis to examine the role of a second-shell residue, Asn276. Of the 19 variants expressed in Escherichia coli, only the Asn276Asp enzyme demonstrated reduced susceptibility to ampicillin/clavulanate (MIC increased from 50/2 --> 50/8 microg/mL) while maintaining high-level resistance to ampicillin (MIC = 8192 microg/mL). Steady-state kinetic analyses of Asn276Asp revealed slightly diminished k(cat)/K(m) for all substrates tested. In contrast, we observed a 5-fold increase in K(i) for clavulanate (7.4 +/- 0.9 microM for Asn276Asp vs 1.4 +/- 0.2 microM for SHV-1) and a 40% reduction in k(inact)/K(I) (0.013 +/- 0.002 microM(-1 )s(-1) for Asn276Asp vs 0.021 +/- 0.004 microM(-1) s(-1) for SHV-1). Timed electrospray ionization mass spectrometry of clavulanate-inhibited SHV-1 and SHV Asn276Asp showed nearly identical mass adducts, arguing for a similar pathway of inactivation. Molecular modeling shows that novel electrostatic interactions are formed between Arg244Neta2 and both 276AspOdelta1 and Odelta2; these new forces restrict the spatial position of Arg244, a residue important in the recognition of the C(3)/C(4) carboxylate of beta-lactam substrates and inhibitors. Testing the functional consequences of this interaction, we noted considerable free energy costs (+DeltaDeltaG) for substrates and inhibitors. A rigid carbapenem (meropenem) was most affected by the Asn276Asp substitution (46-fold increase in K(i) vs SHV-1). We conclude that residue 276 is an important second-shell residue in class A beta-lactamase-mediated resistance to substrates and inhibitors, and only Asn is able to precisely modulate the conformational flexibility of Arg244 required for successful

  19. Demand of authorization to create the 'Flamanville 3' Basis Nuclear Installation. Synthesis report of the technical examination; Demande d'autorisation de creation de l'INB 'Flamanville 3'. Rapport de synthese de l'examen technique

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-02-15

    The present report has for objective to present to the College of Asn a synthesis of the technical instruction piloted by the services of Asn and realized by their technical supports (I.R.S.N., G.P.R., S.P.N.) during the period 2001-2006. After a reminder of the conditions of the examination of the safety options of the project EPR made between 1993 and 2000, this report explains the progress and the modalities of the instruction realized from 2001 till 2006. It draws up then, besides a notice of the Asn services at request of creation authorization, a synthesis of the technical examination realized according to axes presented on the fig 1. Finally, it presents the main lines of the examination that it would stay to realize if the creation authorization was delivered. (N.C.)

  20. Study of thick, nuclear-compensated silicon detectors; Etude des detecteurs epais au silicium compense nucleairement

    Energy Technology Data Exchange (ETDEWEB)

    Le Coroller, Y. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-09-01

    A study is made here, from the point of view of the realization and the performance, of thick nuclear-compensated silicon detectors. After recalling the need for compensation and reviewing the existing methods, the author describes in detail the controlled realization of thick detectors by nuclear compensation from the theoretical and experimental points of view. The practical precautions which should be observed are given: control of the homogeneity of the starting material, control of the evolution of the compensation, elimination of parasitic processes. The performances of the detectors obtained are then studied: electrical characteristics (current, life-time) on the one hand, detection and spectrometry of penetrating radiations on the other hand. The results show, that the compensated diodes having an effective thickness of two millimeters operate satisfactorily as detectors for applied voltages of about 500 volts. The resolutions observed are then about 2 per cent for mono-energetic electrons and about 4 per cent for the gamma; they can be improved by the use of a pre-amplifier of very low background noise. (author) [French] Les detecteurs epais au silicium compense nucleairement sont etudies ici du double point de vue realisation et performances. Apres un rappel sur la necessite de la compensation et les procedes existants, la realisation controlee des detecteurs epais par compensation nucleaire est decrite en detail sous l'aspect theorique et l'aspect experimental. On met en evidence les precautions a prendre dans la pratique: controle de l'homogeneite du materiau de base, controle de l'evolution de la compensation, elimination des processus parasites. On etudie ensuite les performances de detecteurs obtenus : caracteristiques electriques (courant, duree de vie) d'une part, d'autre part detection et spectrometrie des rayonnements penetrants. Les resultats montrent que les diodes compensees ayant une epaisseur utile de deux

  1. Neutron noise in nuclear reactors; Le bruit neutronique des reacteurs nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Blaquiere, A. [Institut National des Sciences et Techniques Nucleaires (France); Pachowska, R. [Universite Technique de Varsovie (Poland)

    1961-06-15

    The power of a nuclear reactor, in the operating conditions, presents fluctuations due to various causes. This random behaviour can be included in the study of 'noises'. Among other sources of noise, we analyse hereafter the fluctuations due: a) to the discontinuous emissions of neutrons from an independent source; b) to the multiplication of neutrons inside the reactor. The method which we present makes use of the analogies between the rules governing a nuclear reactor in operation and a number of radio-electrical systems, in particular the feed-back loops. The reactor can be characterized by its 'passing band' and is described as a system submitted to a sequence of random pulses. In non linear operating condition, the effect of neutron noise is defined by means of a non-linear functional, this theory is thus related to previous works the references of which are given at the end of the present report. This leads us in particular in the case of nuclear reactors to some results given by A. Blaquiere in the case of radio-electrical loops. (author) [French] La puissance d'un reacteur nucleaire, dans les conditions du regime, est affectee de fluctuations dont les causes sont tres diverses. Ce comportement aleatoire rentre dans le cadre general de l'etude des 'bruits'. Entre autres sources ce bruit, nous analysons ici les fluctuations dues: a) a l'emission discontinue des neutrons provenant d'une source autonome; b) a la multiplication des neutrons au sein du reacteur. La methode que nous introduisons exploite les analogies entre les lois qui regissent un reacteur nucleaire au regime et certains systemes radioelectriques, en particulier les circuits a boucle de reaction. Le reacteur est caracterise par sa 'bande passante' et est decrit comme un systeme soumis a une succession d'impulsions aleatoires. Dans les conditions de fonctionnement non lineaires, l'effet du bruit neutronique est precise en utilisant une fonctionnelle non lineaire, ce qui relie cette theorie a

  2. Study of thick, nuclear-compensated silicon detectors; Etude des detecteurs epais au silicium compense nucleairement

    Energy Technology Data Exchange (ETDEWEB)

    Le Coroller, Y [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-09-01

    A study is made here, from the point of view of the realization and the performance, of thick nuclear-compensated silicon detectors. After recalling the need for compensation and reviewing the existing methods, the author describes in detail the controlled realization of thick detectors by nuclear compensation from the theoretical and experimental points of view. The practical precautions which should be observed are given: control of the homogeneity of the starting material, control of the evolution of the compensation, elimination of parasitic processes. The performances of the detectors obtained are then studied: electrical characteristics (current, life-time) on the one hand, detection and spectrometry of penetrating radiations on the other hand. The results show, that the compensated diodes having an effective thickness of two millimeters operate satisfactorily as detectors for applied voltages of about 500 volts. The resolutions observed are then about 2 per cent for mono-energetic electrons and about 4 per cent for the gamma; they can be improved by the use of a pre-amplifier of very low background noise. (author) [French] Les detecteurs epais au silicium compense nucleairement sont etudies ici du double point de vue realisation et performances. Apres un rappel sur la necessite de la compensation et les procedes existants, la realisation controlee des detecteurs epais par compensation nucleaire est decrite en detail sous l'aspect theorique et l'aspect experimental. On met en evidence les precautions a prendre dans la pratique: controle de l'homogeneite du materiau de base, controle de l'evolution de la compensation, elimination des processus parasites. On etudie ensuite les performances de detecteurs obtenus : caracteristiques electriques (courant, duree de vie) d'une part, d'autre part detection et spectrometrie des rayonnements penetrants. Les resultats montrent que les diodes compensees ayant une epaisseur utile de deux millimetres fonctionnent

  3. Review of declarations received by the AFSSAPS and the ASN on the account of radio-vigilance (external radiotherapy). July 2007 - June 2008

    International Nuclear Information System (INIS)

    2009-09-01

    After a presentation of the procedure of declaration of significant radiation protection events, of the ASN-SFRO event scale, and of the indication procedure related to material vigilance, this report proposes a review and an analysis of significant radioprotection and material vigilance events which have been declared between July 2007 and June 2008. The assessment of radiation protection events declared to the ASN is as well quantitative (distribution in time, geographical distribution, status of declaring centres, declaration delays, classification according to the ASN-SFRO scale) as qualitative (origin, event typology, stage of the treatment process at which the event occurred and has been detected, personnel having detected the event, communication about events). The analysis of material vigilance events addresses the evolution of their number, their distribution in terms of declarer type, of radiotherapy equipment, or of criticality level, and so on. A review of hybrid accidents is proposed (concerned equipment, declarer origin, consequences of the declarations, classification on the ASN-SFRO scale)

  4. Employee coaching and counseling program metode alternatif untuk optimalisasi human capital pada pegawai aparatur sipil negara (ASN

    Directory of Open Access Journals (Sweden)

    Marina Sulastiana

    2017-06-01

    Full Text Available State Civil Servants Apparatus (ASN have to be more integrity, professional, neutral and capable to carrying out a public service to the community. It was an important one that can be optimized through development of human capital. Based on previous research investigated role of Human Capital towards Services and performance of Public Service, shows that staff and head divison level only has moderate degree of human capital. While, Emotional Capital was a most dominan aspect in Human Capital. Otherwise, Social Capital aspects results in the low level. It comes with consequences to optimized them through psychological intervention with group Employee Coaching and Counseling Program (ECCP. This study was action research, experimental one group preteset and postest design. The result shows that ECCP was contribute effectively to enhance Human Capital, particularly in Emotional Capital optimization.

  5. Statistical pulses generator. Application to nuclear instrumentation (1962); Generateur d'impulsions aleatoires. Application a l'instrumentation nucleaire (1962)

    Energy Technology Data Exchange (ETDEWEB)

    Beranger, R [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1962-07-01

    This report describes a random pulses generator adapted to nuclear instrumentation. After a short survey on the statistical nature of electronic signals, the different ways for generating pulses with a Poisson's time-distribution are studied. The final generator built from a gaseous thyratron in a magnetic field is then described. Several tests are indicated : counting-rate stability, Pearson's criterion, distribution of time-intervals. Applications of the generator in 'whole testing' of nuclear instrumentation are then indicated for sealers, dead time measurements, time analyzers. In this application, pulse-height spectrums have been made by Poissonian sampling of a recurrent or random low-frequency signal. (author) [French] Cette etude decrit un generateur d'impulsions aleatoires et ses applications a l'instrumentation nucleaire. Apres un bref rappel sur la nature statistique des signaux en electronique nucleaire, sont passes en revue les principaux moyens d'obtenir des impulsions distribuees en temps suivant une loi de Poisson. Le generateur utilisant un thyratron a gaz dans un champ magnetique est ensuite decrit; diverses methodes de test sont appliquees (stabilite du taux de comptage, criterium de Pearson, spectre des intervalles ds temps). Les applications du generateur a l'electronique nucleaire dans le domaine des 'essais globaux' sont indiques: test des echelles de comptage et mesure des temps morts, test des analyseurs en temps apres division du taux de comptage par une puissance de deux, test des analyseurs multicanaux en amplitude. Pour cette derniere application, on a realise des spectres d'amplitudes suivant une loi connue, par echantillonnage poissonien d'un signal basse frequence recurrent ou aleatoire. (auteur)

  6. Molten salts in nuclear reactors; Les sels fondus dans les reacteurs nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Dirian, J; Saint-James, [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1959-07-01

    Collection of references dealing with the physicochemical studies of fused salts, in particular the alkali and alkali earth halides. Numerous binary, ternary and quaternary systems of these halides with those of uranium and thorium are examined, and the physical properties, density, viscosity, vapour pressure etc... going from the halides to the mixtures are also considered. References relating to the corrosion of materials by these salts are included and the treatment of the salts with a view to recuperation after irradiation in a nuclear reactor is discussed. (author) [French] Bibliographie regroupant l'etude physico-chimique des sels fondus, en particulier des halogenures alcalins et alcalino-terreux. On etudie de nombreux systemes binaires, ternaires et quaternaires de ces halogenures avec des halogenures d'uranium, et de thorium. On etudie egalement les proprietes physiques des halogenures ou des melanges d'halogenures (densite, viscosite, tension de vapeur, etc...). On donne egalement des references quant a la corrosion des materiaux par ces sels, et le traitement de ceux-ci en vue de recuperation, apres irradiation dans un reacteur nucleaire. (auteur)

  7. Piles used for the nuclear control of materials; Empilements pour le controle nucleaire des materiaux

    Energy Technology Data Exchange (ETDEWEB)

    Raievski, V; Sautiez, B; Bailly du Bois, B; Tretiakoff, O; Thome, P; Vidal, R; Koppel Martelly, J [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    The devices which make it possible to check on the nuclear qualities of the materials used in reactor construction are described. These verifications bear on substantial masses of materials, following the last stage of their machining. The components found in all these are a graphite pile into which the material to be investigated is inserted, a source of neutrons made up of an Ra-Be system, and a proportional BF{sub 3} counter. The devices described here bear on checking graphite, beryllium oxide and uranium absorption, as well as on a verification of the {sup 235}U content of fuel elements. (author)Fren. [French] On decrit des dispositifs permettant de controler les qualites nucleaires de materiaux utilises dans la construction des piles. Ce controle s'effectue sur des masses importantes de materiaux apres la phase finale d'usinage. Ces dispositifs ont en commun un empilement de graphite recevant le materiau a etudier, une source de neutrons de Ra-Be et un compteur proportionnel a BF{sub 3}. Les dispositifs decrits concernent le controle de l'absorption du graphite, de la glucine et de l'uranium, ainsi que le controle de la teneur en {sup 235}U des elements de combustion. (auteur)

  8. Underground nuclear explosions. Geological survey of the cavities; Explosions nucleaires souterraines etude geologique des cavites

    Energy Technology Data Exchange (ETDEWEB)

    Faure, J [Commissariat a l' Energie Atomique, Bruyeres-le-Chatel (France). Centre d' Etudes

    1969-07-01

    A geological survey of underground nuclear explosions makes it possible to determine the main characteristics of the cavity formed. The lower portion is spherical; the same was very likely true of the roof, which collapses in the majority of media with the exception of rock-salt. Its radius, for a given bomb size, can vary by a factor of two according to the type of rock. The lay-out of its contents depends on the characteristics of the solid and liquid products at the moment of the roof collapse; according to the medium involved, mixing of the rubble and the mud-flow occurs (granite) or does not occur (tuff and alluvia). In all media, the average physical properties can be evaluated. (author) [French] L'etude geologique d'explosions nucleaires souterraines permet de determiner les principaux caracteres de la cavite creee. Sa partie inferieure est spherique; il en etait vraisemblablement de meme de sa voute, effondree dans la plupart des milieux a l'exception du sel gemme. Son rayon, a energie d'engin egale, varie selon les roches du simple au double. La disposition de son contenu depend des caracteristiques des produits solides et liquides au moment de la chute du toit; selon le cas, il n'y a pas (tuf et alluvions) ou il y a (granite) melange des eboulis et des laves. Dans tous les milieux, les proprietes physiques moyennes peuvent etre evaluees. (auteur)

  9. Production of nuclear graphite in France; Production de graphite nucleaire en France

    Energy Technology Data Exchange (ETDEWEB)

    Legendre, P; Mondet, L [Societe Pechiney, 74 - Chedde (France); Arragon, Ph; Cornuault, P; Gueron, J; Hering, H [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1955-07-01

    The graphite intended for the construction of the reactors is obtained by the usual process: confection of a cake from coke of oil and tar, cooked (in a electric oven) then the product of cook is graphitized, also by electric heating. The use of the air transportation and the control of conditions cooking and graphitization have permitted to increase the nuclear graphite production as well as to better control their physical and mechanical properties and to reduce to the minimum the unwanted stains. (M.B.) [French] Le graphite destine a la construction des reacteurs est obtenu par le procede usuel: confection d'une pate a partir de coke de petrole et de brai, cuisson de cette pate (au four electrique) puis graphitation du produit cuit, egalement par chauffage electrique. L'usage du transport pneumatique et le controle des conditions cuisson et de graphitation ont permit d'augmenter la production de graphite nucleaire ainsi que de mieux controler ses proprietes physiques et mecaniques et de reduire au minimum les souillures accidentelles. (M.B.)

  10. Contribution to the study of nuclear resonance in magnetic media (1963); Contribution a l'etude de la resonance nucleaire dans les milieux magnetique (1963)

    Energy Technology Data Exchange (ETDEWEB)

    Hartmann-Boutron, F [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1963-06-15

    An attempt is made to interpret the results of nuclear magnetic resonance experiments made by various workers on ferro and ferrimagnetic compounds of the iron group. The problems encountered are the following: effects of the dipolar fields and the hyperfine structure anisotropy; signal intensity; frequency pulling due to the Suhl-Nakamura interaction between nuclear spins ; nuclear relaxation and ferrimagnetic resonance in single domain samples of impure YIG; nuclear relaxation in the Bloch walls of insulators. The results of our calculations are generally in good agreement with experiment. (author) [French] On se propose d'interpreter les resultats d'experiences de resonance magnetique nucleaire fates par divers auteurs sur des composes ferro et ferrimagnetiques du groupe du fer. Les problemes abordes sont les suivants: effets des champs dipolaires et de l'anisotropie de structure hyperfine; intensite des signaux; deplacement de frequence du a l'interaction de Suhl-Nakamura entre spins nucleaires; relaxation nucleaire et resonance ferrimagnetique dans les echantillons monodomaines de grenat de fer et d'yttrium impur; relaxation nucleaire dans les parois de Bloch des isolants. Les resultats des calculs sont generalement en bon accord avec l'experience. (auteur)

  11. Contribution to the study of nuclear resonance in magnetic media (1963); Contribution a l'etude de la resonance nucleaire dans les milieux magnetique (1963)

    Energy Technology Data Exchange (ETDEWEB)

    Hartmann-Boutron, F. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1963-06-15

    An attempt is made to interpret the results of nuclear magnetic resonance experiments made by various workers on ferro and ferrimagnetic compounds of the iron group. The problems encountered are the following: effects of the dipolar fields and the hyperfine structure anisotropy; signal intensity; frequency pulling due to the Suhl-Nakamura interaction between nuclear spins ; nuclear relaxation and ferrimagnetic resonance in single domain samples of impure YIG; nuclear relaxation in the Bloch walls of insulators. The results of our calculations are generally in good agreement with experiment. (author) [French] On se propose d'interpreter les resultats d'experiences de resonance magnetique nucleaire fates par divers auteurs sur des composes ferro et ferrimagnetiques du groupe du fer. Les problemes abordes sont les suivants: effets des champs dipolaires et de l'anisotropie de structure hyperfine; intensite des signaux; deplacement de frequence du a l'interaction de Suhl-Nakamura entre spins nucleaires; relaxation nucleaire et resonance ferrimagnetique dans les echantillons monodomaines de grenat de fer et d'yttrium impur; relaxation nucleaire dans les parois de Bloch des isolants. Les resultats des calculs sont generalement en bon accord avec l'experience. (auteur)

  12. NMR structure determination of a synthetic analogue of bacillomycin Lc reveals the strategic role of L-Asn1 in the natural iturinic antibiotics

    Science.gov (United States)

    Volpon, Laurent; Tsan, Pascale; Majer, Zsuzsa; Vass, Elemer; Hollósi, Miklós; Noguéra, Valérie; Lancelin, Jean-Marc; Besson, Françoise

    2007-08-01

    Iturins are a group of antifungal produced by Bacillus subtilis. All are cyclic lipopeptides with seven α-amino acids of configuration LDDLLDL and one β-amino fatty acid. The bacillomycin L is a member of this family and its NMR structure was previously resolved using the sequence Asp-Tyr-Asn-Ser-Gln-Ser-Thr. In this work, we carefully examined the NMR spectra of this compound and detected an error in the sequence. In fact, Asp1 and Gln5 need to be changed into Asn1 and Glu5, which therefore makes it identical to bacillomycin Lc. As a consequence, it now appears that all iturinic peptides with antibiotic activity share the common β-amino fatty acid 8- L-Asn1- D-Tyr2- D-Asn3 sequence. To better understand the conformational influence of the acidic residue L-Asp1, present, for example in the inactive iturin C, the NMR structure of the synthetic analogue SCP [cyclo ( L-Asp1- D-Tyr2- D-Asn3- L-Ser4- L-Gln5- D-Ser6- L-Thr7-β-Ala8)] was determined and compared with bacillomycin Lc recalculated with the corrected sequence. In both cases, the conformers obtained were separated into two families of similar energy which essentially differ in the number and type of turns. A detailed analysis of both cyclopeptide structures is presented here. In addition, CD and FTIR spectra were performed and confirmed the conformational differences observed by NMR between both cyclopeptides.

  13. Analytic catalog for the use of the nuclear physicists; Repertoire analytique a l'usage des physiciens nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Ballini, R.; Barloutaud, R.; Bernas, R.; Chaminade, R.; Cohen, R.; Conjeaud, M.; Cotton, E.; Faraggi, H.; Grjebine, T.; Laboulaye, H. de; Lehmann, P.; Leveque, A.; Levi, C.; Moreau, J.; Naggiar, V.; Olkowsky, J.; Papineau, L.; Papineau, L.; Prugne, P.; Schuhl, C.; Szteinsznaider, D.; Tzara, C.; Valladas, G. [Commissariat a l' Energie Atomique, Saclay(France). Centre d' Etudes Nucleaires; Marty, N.; Renard, G. [College de France, Lab. de Chimie Nucleaire (France)

    1952-07-01

    The problem of the documentation in nuclear physics becomes constantly more complex. Every week brings its share of publications, always more numerous and more varied. To remedy to this problem, we tried, at the Nuclear Physics Services of the CEA, to give to the documentation the character of a collective and systematized work. The present report covers the literature appeared between January 1, 1950 and July 1, 1951. (Volume 1: CEA report number 120; Volume 2: CEA report number 184). (M.B.) [French] Le probleme de la documentation en physique nucleaire devient sans cesse plus complexe. Chaque semaine apporte son lot de publications, toujours plus nombreuses et plus diversifiees. C'est pour essayer de porter remede a cet etat de choses que nous avons essaye, au service de Physique Nucleaire du C.E.A., de donner a la documentation le caractere d'un travail collectif systematise. Le present rapport couvre la litterature parue entre le 1 Janvier 1950 et le 1 Juillet 1951. (Tome 1: Rapport CEA numero 120; Tome 2: Rapport CEA numero 184). (M.B.)

  14. Analytic catalog for the use of the nuclear physicists; Repertoire analytique a l'usage des physiciens nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Ballini, R; Barloutaud, R; Bernas, R; Chaminade, R; Cohen, R; Conjeaud, M; Cotton, E; Faraggi, H; Grjebine, T; Laboulaye, H de; Lehmann, P; Leveque, A; Levi, C; Moreau, J; Naggiar, V; Olkowsky, J; Papineau, L; Papineau, L; Prugne, P; Schuhl, C; Szteinsznaider, D; Tzara, C; Valladas, G [Commissariat a l' Energie Atomique, Saclay(France). Centre d' Etudes Nucleaires; Marty, N; Renard, G [College de France, Lab. de Chimie Nucleaire (France)

    1952-07-01

    The problem of the documentation in nuclear physics becomes constantly more complex. Every week brings its share of publications, always more numerous and more varied. To remedy to this problem, we tried, at the Nuclear Physics Services of the CEA, to give to the documentation the character of a collective and systematized work. The present report covers the literature appeared between January 1, 1950 and July 1, 1951. (Volume 1: CEA report number 120; Volume 2: CEA report number 184). (M.B.) [French] Le probleme de la documentation en physique nucleaire devient sans cesse plus complexe. Chaque semaine apporte son lot de publications, toujours plus nombreuses et plus diversifiees. C'est pour essayer de porter remede a cet etat de choses que nous avons essaye, au service de Physique Nucleaire du C.E.A., de donner a la documentation le caractere d'un travail collectif systematise. Le present rapport couvre la litterature parue entre le 1 Janvier 1950 et le 1 Juillet 1951. (Tome 1: Rapport CEA numero 120; Tome 2: Rapport CEA numero 184). (M.B.)

  15. Study of the chimney produced by an underground nuclear explosion; Etude de la cheminee creee par une explosion nucleaire souterraine

    Energy Technology Data Exchange (ETDEWEB)

    Derlich, S [Commissariat a l' Energie Atomique, Bruyeres-le-Chatel (France). Centre d' Etudes

    1969-07-01

    Underground nuclear explosions lead to the formation of a cavity which is roughly of spherical shape. The roof of this cavity is unstable and collapses in most cases, leading to the formation of a chimney. The height and the diameter depend on the energy of the charge and on the nature of the surroundings. The chronology of the various stages can be determined by seismic observations. The interior of the chimney is filled, either partially or completely, with rubble earth. This phenomenon is of great importance as far as the use of nuclear explosions for industrial applications is concerned. (author) [French] Les explosions nucleaires souterraines creent une cavite de forme grossierement spherique. La voute de cette cavite est instable et s'effondre dans la plupart des cas, donnant lieu a la formation d'une cheminee. La hauteur et le diametre sont fonction de l'energie du tir et de la nature du milieu. La chronologie des evenements peut etre determinee par des observations seismiques. L'interieur des cheminees est occupe, en partie ou en totalite, par des eboulis. Ce phenomene presente un grand interet pour l'utilisation des explosions nucleaires a des fins industrielles. (auteur)

  16. General phenomenology of underground nuclear explosions; Phenomenologie generale des explosions nucleaires souterraines

    Energy Technology Data Exchange (ETDEWEB)

    Derlich, S; Supiot, F [Commissariat a l' Energie Atomique, Bruyeres-le-Chatel (France). Centre d' Etudes

    1969-07-01

    An essentially qualitatively description is given of the phenomena related to underground nuclear explosions (explosion of a single unit, of several units in line, and simultaneous explosions). In the first chapter are described the phenomena which are common to contained explosions and to explosions forming craters (formation and propagation of a shock-wave causing the vaporization, the fusion and the fracturing of the medium). The second chapter describes the phenomena related to contained explosions (formation of a cavity with a chimney). The third chapter is devoted to the phenomenology of test explosions which form a crater; it describes in particular the mechanism of formation and the different types of craters as a function of the depth of the explosion and of the nature of the ground. The aerial phenomena connected with explosions which form a crater: shock wave in the air and focussing at a large distance, and dust clouds, are also dealt with. (authors) [French] On donne une description essentiellement qualitative des phenomenes lies aux explosions nucleaires souterraines (explosion d'un seul engin, d'engins en ligne et explosions simultanees). Dans un premier chapitre sont decrits les phenomenes communs aux explosions contenues et aux explosions formant un cratere (formation et propagation d'une onde de choc provoquant la vaporisation, la fusion et la fracturation du milieu). Le deuxieme chapitre decrit les phenomenes lies aux tirs contenus (formation d'une cavite et d'une cheminee). Le troisieme chapitre est consacre a la phenomenologie des tirs formant un cratere et decrit notamment le mecanisme de formation et les differents types de crateres en fonction de la profondeur d'explosion et de la nature du terrain. Les phenomenes aeriens lies aux explosions formant un cratere: onde de pression aerienne et focalisation a grande distance, nuages de poussieres, sont egalement abordes. (auteurs)

  17. ASN takes position in the in-service follow-up programs of primary and secondary loops of EdF's nuclear power plants

    International Nuclear Information System (INIS)

    2002-01-01

    This decision from the French authority of nuclear safety (ASN) aims at fixing the conditions to be respected by Electricite de France (EdF) during its in-service follow-up programs for the monitoring and preventive maintenance of the primary and secondary cooling loops of EdF's PWR reactors. The components and the particular points to be controlled are listed in appendixes. (J.S.)

  18. Water dynamics of Ser-His-Glu-Cys-Asn powder and effects of moisture absorption on its chemical properties.

    Science.gov (United States)

    Lin, Songyi; Xue, Peiyu; Yang, Shuailing; Li, Xingfang; Dong, Xiuping; Chen, Feng

    2017-08-01

    This study has elucidated moisture dynamics in the soybean peptide, Ser-His-Glu-Cys-Asn (SHECN) powder by using dynamic vapor sorption (DVS) and nuclear magnetic resonance (NMR). We also tried to investigate the effects of moisture absorption on the biological activity and chemical properties of SHECN with some effective methods such as mid-infrared (MIR) spectroscopy and gas chromatography-mass spectrometry (GC-MS). DVS results showed that the moisture absorption of SHECN could reach a maximum of 33%, and the SHECN powder after synthesis actually existed in a trihydrate state of SHECN.3H 2 O. Low-field NMR revealed that three water proportions including strong combined water, binding water and bulk water were involved in SHECN moisture absorption and absored water dominantly existed in the form of combined water. Magnetic resonance imaging (MRI) and MIR spectroscopy results indicated that moisture absorption could change the morphology and structure of SHECN. After moisture absorption at 50% and 75% relative humidity, 19 volatiles were identified by GC-MS analysis. Additionally, this study showed that a part of reductive groups in SHECN was oxidized and its antioxidant ability declined significantly (P moisture absorption. Water absorbed into SHECN powder can significantly change its microstructure and cause its activity to decrease. We must prevent SHECN from absorbing moisture during storage because the water can accelerate the oxidation of samples and promote microbial reactions. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

  19. Radioimmunoassay for Lys8, Asn9, neurotensin 8-13: tissue and subcellular distribution of immunoreactivity in chickens

    International Nuclear Information System (INIS)

    Carraway, R.E.; Ruane, S.E.; Ritsema, R.S.

    1983-01-01

    A sensitive and specific radioimmunoassay (RIA) for Lys8, Asn9, neurotensin 8-13 (LANT-6) has been developed which utilizes 125I-labeled LANT-6 and rabbit antisera raised towards conjugates of synthetic LANT-6 and bovine thyroglobulin. The antiserum described (TG-22) allows the detection of ca 100 fmol of LANT-6 and crossreacts less than 0.01% with chicken or bovine NT. Dose-response relationships for the native (chicken) and synthetic peptides were indistinguishable. Using this assay the distribution of immunoreactive LANT-6 (iLANT-6) through various tissues of the chicken was studied and compared with that of chicken NT (iNT) determined by RIA. Both iNT and ILANT-6 were found primarily in the brain and gastrointestinal tract, however, their regional distributions were found to differ. Subcellular distribution studies in homogenates of chicken brain indicated that both iNT and iLANT-6 were associated with synaptosome-like and vesicle-like particles. In homogenates of small intestine, pancreas and colon iNT and iLANT-6 appeared to be within osmotically sensitive, sedimentable particles. Analyses using high pressure liquid chromatography established that chicken iLANT-6 co-eluted with the synthetic peptide and that similar substances were present in extracts of rat brain and intestine. These results are consistent with ''messenger' roles for these peptides

  20. Lessons learned from events declared to the ASN related to interventional radiology and having occurred during radiation-based acts

    International Nuclear Information System (INIS)

    Lachaume, Jean-Luc

    2014-01-01

    Based on an analysis of events declared to the ASN and inspection observations performed in the field of interventional radiology, this report outlines that the majority of these events could have been avoided and that they result from a lack of culture in radiation protection, notably an unawareness of doses delivered to patients or received by practitioners, and of risks related to exposure to ionizing radiations. The report notably outlines that events are related to a lack of staff and means in the field of patient and personnel radiation protection, an underdeveloped risk management and radiation protection implementation, lacks in the management of delivered or received doses and absence of approaches of professional practice assessment, operator insufficient education, and weaknesses in the management of subcontracted operations. Recommendations are made related to needs in medical radio-physics, identification of acts and patients at risk and definition of patient follow-up modalities, the implementation of an approach of professional practice assessment, the storage of dosimetric data, the improvement of operator technical education, the control of subcontracted operations, and the anticipation of technical and organisational changes

  1. Flexible xxx-asp/asn and gly-xxx residues of equine cytochrome C in matrix-assisted laser desorption/ionization in-source decay mass spectrometry.

    Science.gov (United States)

    Takayama, Mitsuo

    2012-01-01

    The backbone flexibility of a protein has been studied from the standpoint of the susceptibility of amino acid residues to in-source decay (ISD) in matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS). Residues more susceptible to MALDI-ISD, namely Xxx-Asp/Asn and Gly-Xxx, were identified from the discontinuous intense peak of c'-ions originating from specific cleavage at N-Cα bonds of the backbone of equine cytochrome c. The identity of the residues susceptible to ISD was consistent with the known flexible backbone amides as estimated by hydrogen/deuterium exchange (HDX) experiments. The identity of these flexible amino acid residues (Asp, Asn, and Gly) is consistent with the fact that these residues are preferred in flexible secondary structure free from intramolecular hydrogen-bonded structures such as α-helix and β-sheet. The MALDI-ISD spectrum of equine cytochrome c gave not only intense N-terminal side c'-ions originating from N-Cα bond cleavage at Xxx-Asp/Asn and Gly-Xxx residues, but also C-terminal side complement z'-ions originating from the same cleavage sites. The present study implies that MALDI-ISD can give information about backbone flexibility of proteins, comparable with the protection factors estimated by HDX.

  2. Flexible Xxx–Asp/Asn and Gly–Xxx Residues of Equine Cytochrome c in Matrix-Assisted Laser Desorption/Ionization In-Source Decay Mass Spectrometry

    Science.gov (United States)

    Takayama, Mitsuo

    2012-01-01

    The backbone flexibility of a protein has been studied from the standpoint of the susceptibility of amino acid residues to in-source decay (ISD) in matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS). Residues more susceptible to MALDI-ISD, namely Xxx–Asp/Asn and Gly–Xxx, were identified from the discontinuous intense peak of c′-ions originating from specific cleavage at N–Cα bonds of the backbone of equine cytochrome c. The identity of the residues susceptible to ISD was consistent with the known flexible backbone amides as estimated by hydrogen/deuterium exchange (HDX) experiments. The identity of these flexible amino acid residues (Asp, Asn, and Gly) is consistent with the fact that these residues are preferred in flexible secondary structure free from intramolecular hydrogen-bonded structures such as α-helix and β-sheet. The MALDI-ISD spectrum of equine cytochrome c gave not only intense N-terminal side c′-ions originating from N–Cα bond cleavage at Xxx–Asp/Asn and Gly–Xxx residues, but also C-terminal side complement z′-ions originating from the same cleavage sites. The present study implies that MALDI-ISD can give information about backbone flexibility of proteins, comparable with the protection factors estimated by HDX. PMID:24349908

  3. Stěžejní východiska a koncepce současné anglické náboženské pedagogiky

    Directory of Open Access Journals (Sweden)

    Karim Sidibe

    2017-08-01

    Full Text Available Tento článek si klade za cíl analyzovat didaktické koncepce výuky náboženství pěti hlavních teoretiků současné anglické náboženské pedagogiky, Harolda Loukese, Niniana Smarta, Davida Haye, Cliva Errickera a Andrewa Wrighta. Loukes a Smart položili základy současné náboženské pedagogiky v Anglii v 60. letech 20. století. Loukes využil poznatky vývojové psychologie a Smart výuku sekularizoval. Hayovo pojetí z 80. let 20. století akcentuje niternou duchovní skutečnost žáků. V současné době Erricker aplikuje postmoderní filosofická východiska na výuku a akcentuje individualitu a nezávislost žáků, zatímco Wright vychází z filosofických východisek kritického realismu a akcentuje nutnost teologické a filosofické diskuze na hodinách náboženství.

  4. A mathematical model for cost of maritime transport. Application to competitiveness of nuclear vessels; Modele mathematique du cout de transport maritime application a la competitivite du navire nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Dorval, C [Commissariat a l' Energie Atomique, 75 - Paris (France)

    1966-05-01

    In studying the competitiveness of a nuclear merchant vessel, economic assessments in terms of figures were discarded in favor of a simplified model, which gives a clearer idea of the mechanism of the comparison between alternative vessels and the particular influence of each parameter. An expression is formulated for the unit cost per ton carried over a given distance as a function of the variables (speed and deadweight tonnage) and is used to determine the optima for conventional and nuclear vessels. To represent the freight market involved in the optimization studies, and thus in the competitiveness computation, two cases are taken into account: the tonnage to be carried annually is limited, and the tonnage to be carried annually is not limited. In both cases the optima are calculated and compared for a conventional and a nuclear vessel. Competitiveness curves are plotted as a function of the ratios of nuclear and conventional fuel costs and nuclear and conventional marginal power costs. These curves express the limiting values of the above two ratios for which the transport costs of the nuclear and conventional vessels are equal. The competitiveness curves vary considerably according to the hypothesis adopted for the freight market and the limit of tonnage carried annually. (author) [French] Pour etudier la competitivite du navire marchand nucleaire, plutot que de nous livrer a des evaluations economiques chiffrees, discutables dans l'etat actuel des etudes, nous utilisons un modele simplifie permettant de mieux saisir le mecanisme de la comparaison des navires et l'influence particuliere de chaque parametre. Nous etablissons une expression du cout unitaire de la tonne transportee sur un parcours donne en fonction des variables vitesse et port en lourd. Et nous l'utilisons pour determiner les optima des navires classiques et nucleaires. Pour representer le marche du fret qui intervient dans les etudes d'optimisation, et donc dans la recherche de la

  5. Contribution to the study of thermal mixing between nuclear spin systems; Contribution a l'etude du melange thermique entre systemes de spins nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Goldmann, M [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1967-02-15

    This work describes methods of dynamic nuclear polarization in solids based on the thermal mixing between nuclear spin systems. The description of the thermal mixing processes involves most of the fundamental aspects of the spin temperature theory. The experiments, conducted with paradichlorobenzene and para-dibromobenzene, yield a detailed confirmation of the theoretical predictions. (author) [French] Ce travail decrit des methodes de polarisation dynamique nucleaire dans les solides basees sur le melange thermique entre systemes de spins nucleaires. La description des processus de melange thermique met en jeu la plupart des aspects fondamentaux de la theorie de la temperature de spin. Les experiences, realisees avec du paradichlorobenzene et du paradibromobenzene, apportent une confirmation detaillee des previsions theoriques. (auteur)

  6. Statistical treatment of data. Application to nuclear electronics; Traitement des informations en regime statistique. Applications a l'electronique nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Sicard, F [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1960-07-01

    In this report the data of probability calculations are applied to the analyses of counting losses in experiments on chance events encountered in nuclear physics. The distribution of time intervals according to Poisson's law is studied and various applications of this are given: calculation of counting losses on a scale preceded by a fast de-multiplying circuit, decrease of the counting rate on the multichannel selectors, recording of statistical distribution phenomena on magnetic bands. (author) [French] Ce rapport applique les donnees du calcul des probabilites a l'analyse des pertes de comptage dans les experiences sur des evenements aleatoires rencontres en physique nucleaire. La distribution des intervalles de temps suivant une loi de Poisson est etudiee et differentes applications en sont donnees: calcul des pertes de comptage sur une echelle precedee d'un circuit de demultiplication rapide, diminution du taux de comptage sur les selecteurs multicanaux, enregistrement de phenomenes a distribution statistique sur bandes magnetiques. (auteur)

  7. Economic consequences of the Swiss 'Sortir du nucleaire' and 'Moratoire-plus' popular initiatives - Analysis using a balanced model

    International Nuclear Information System (INIS)

    Mueller, A.; Wickart, M.; Van Nieuwkoop, R.

    2001-01-01

    This article is a short version of the ENET number 210359. This report for the Swiss Federal Office of Energy (SFOE) presents the results of a study made to assess the economic consequences of two models for the opting out of nuclear energy in Switzerland, as proposed in two popular initiatives. The 'Sortir du nucleaire' (electricity without atomic power) initiative calls for the shutting down of the existing nuclear power stations and the 'Moratoire-plus' initiative calls for a stop on the building of new atomic power stations for 10 years. The method used for assessing the costs and benefits resulting if the initiatives were accepted in a public vote is described. Basic assumptions made on further factors concerning the electricity and energy markets are discussed. Results of analyses made for various scenarios with respect to CO 2 emissions are presented and include discussions on risk costs, effects on employment and welfare aspects

  8. Dosimeter calibration facilities and methods at the Radiation Measurement Laboratory of the Centre d'etudes nucleaires, Grenoble

    International Nuclear Information System (INIS)

    Choudens, H. de; Herbaut, Y.; Haddad, A.; Giroux, J.; Rouillon, J.; CEA Centre d'Etudes Nucleaires de Grenoble, 38

    1975-01-01

    At the Centre d'etudes nucleaires, Grenoble, the Radiation Measurement Laboratory, which forms part of the Environmental Protection and Research Department, serves the entire Centre for purposes of dosimetry and the calibration of dose meters. The needs of radiation protection are such that one must have facilities for checking periodically the calibration of radiation-monitoring instruments and developing special dosimetry techniques. It was thought a good idea to arrange for the dosimetry and radiation protection team to assist other groups working at the Centre - in particular, the staff of the biology and radiobiology laboratories - and also bodies outside the framework of the French Commissariat a l'energie atomique. Thus, technical collaboration has been established with, for example, Grenoble's Centre hospitalier universitaire (university clinic), which makes use of the facilities and skills available at the Radiation Measurement Laboratory for solving special dosimetry problems. With the Laboratory's facilities it is possible to calibrate dose meters for gamma, beta and neutron measurements

  9. Nuclear Safety and Radiation Protection in France in 2005; La surete nucleaire et la radioprotection en France en 2005. Dossier de presse

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-04-15

    In 2005, the Asn pursued its significant investment in radiation protection and reaffirms its ambition to become as efficient in radiation protection as it is in nuclear safety as of 2009. 2005 was a year of great progress for the Asn as it consolidated its organisation and working methods, in accordance with the 2005-2007 strategic plan it set for itself. The Asn continued progress in the field of radiation protection has given rise to various new regulations to improve the legislative and regulatory framework in this area. The Asn plans to step up its efforts to ensure better monitoring of patient exposure to ionizing radiation and to provide better management of radon-related risks, particularly in housing. Fully aware that its newfound power in this area requires outside evaluation, the Asn has asked the International Atomic Energy Agency (IAEA) to organize an I.R.R.S. (Integrated Regulatory Review Service) assignment consisting of a peer-conducted audit. The IAEA has confirmed that this audit will take place in November 2006. (N.C.)

  10. Biologically active and C-amidated hinnavinII-38-Asn produced from a Trx fusion construct in Escherichia coli.

    Science.gov (United States)

    Kang, Chang Soo; Son, Seung-Yeol; Bang, In Seok

    2008-12-01

    The cabbage butterfly (Artogeia rapae) antimicrobial peptide hinnavinII as a member of cecropin family is synthesized as 37 residues in size with an amidated lysine at C-terminus and shows the humoral immune response to a bacterial invasion. In this work, a synthetic gene for hinnavinII-38-Asn (HIN) with an additional amino acid asparagine residue containing amide group at C-terminus was cloned into pET-32a(+) vector to allow expression of HIN as a Trx fusion protein in Escherichia coli strain BL21 (DE3) pLysS. The resulting expression level of the fusion protein Trx-HIN could reach 15-20% of the total cell proteins and more than 70% of the target proteins were in soluble form. The fusion protein could be purified successfully by HiTrap Chelating HP column and a high yield of 15 mg purified fusion protein was obtained from 80 ml E. coli culture. Recombinant HIN was readily obtained by enterokinase cleavage of the fusion protein followed by FPLC chromatography, and 3.18 mg pure active recombinant HIN was obtained from 80 ml culture. The molecular mass of recombinant HIN determined by MALDI-TOF mass spectrometer is 4252.084 Da which matches the theoretical mass (4252.0 Da) of HIN. Comparing the antimicrobial activities of the recombinant hinnavinII with C-amidated terminus to that without an amidated C-terminus, we found that the amide of asparagine at C-terminus of hinnavinII improved its potency on certain microorganism such as E. coli, Enterobacter cloacae, Bacillus megaterium, and Staphylococcus aureus.

  11. Project of law authorizing the approval of the agreement between the government of the French republic and the government of the Russian federation relative to the civil liability by way of nuclear damage owing to the supply of materials from the French republic devoted to nuclear facilities in the Russian federation; Projet de loi autorisant l'approbation de l'accord entre le gouvernement de la republique francaise et le gouvernement de la federation de Russie relatif a la responsabilite civile au titre de dommages nucleaires du fait de fournitures en provenance de la republique francaise destinees a des installations nucleaires en federation de Russie

    Energy Technology Data Exchange (ETDEWEB)

    Raffarin, J.P.; Villepin, D. de

    2002-07-01

    An agreement between France and Russia was signed on June 20, 2000 about the civil liability of Russia because of the supply of French material devoted to Russian nuclear facilities. This agreement was necessary because Russia do not belong to any of the two big international civil liability systems relative to nuclear energy, i.e. the Paris convention from July 29, 1960 (in the OECD framework) and the Vienna convention from May 21, 1963 (in the IAEA framework). This agreement offers a protection to the French nuclear suppliers against any damage claims in the case of a nuclear accident occurring on the Russian federation territory. This project of law aims at approving this agreement. (J.S.)

  12. Progress report: nuclear safety and radiation protection in France in 2005; Rapport annuel: la surete nucleaire et la radioprotection en France en 2005

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    The Asn (Nuclear safety authority) considers that 2005 was a satisfactory year in terms of nuclear safety and radiation protection. However, further progress can and must be made. 2005 was a year of great progress for the Asn as it consolidated its organisation and working methods, in accordance with the 2005-2007 strategic plan it set for itself. The Asn continued progress in the field of radiation protection has given rise to various new regulations to improve the legislative and regulatory framework in this area. 2005 was marked by significant progress in the process of harmonizing national nuclear safety policies Against a backdrop of the preparation of a bill on management of radioactive materials and waste, to be presented to Parliament in March 2006, 2005 was a year of important milestones. The Asn control activities encompass the following seven areas: development of general regulations for nuclear safety and radiation protection; management of individual authorization requests and receipt of declarations; inspection of nuclear activities; organisation of radiological surveillance of individuals and of the environment; preparation for management of emergency situations and implementation if necessary; contribution to public information on nuclear safety and radiation protection; determination of the French position within international community. Main topics in 2005: government bill on transparency and security in the nuclear field; the challenges and ambitions of the Asn; controlling exposure to radon; EPR Reactor Project Safety; working towards a law on radioactive waste in 2006; I.R.R.T.: an international audit of Asn in 2006; harmonization of nuclear safety in Europe; Chernobyl: what has been achieved over the past 20 years; informing the Public; internal authorizations. (N.C.)

  13. Especificação e Implementação de Templates GDMO e Tipos ASN 1 para Linguagem C++

    OpenAIRE

    Junior, Rivalino Matias; Specialski, Elizabeth Sueli; May, Karina; Ropelato, Patricia

    1996-01-01

    Este artigo descreve a especificação e implementação de regras para o mapeamento de templates GDMO (GuideUnes lor the Definition 01 Managed Objects) [1 l, além da implementação dos tipos ASN.1, em linguagem de programação C++[2l. Estas regras serao utilizadas no mapeamentotemplate - GDMO para classes (dass) em C++, linguagem utilizada em todo o projeto da Plataforma de Gerencia da Rede Local UFSC, a qual segue o modelo de gerenciamento de redes OSI.

  14. Asn563Ser polymorphism of CD31/PECAM-1 is associated with atherosclerotic cerebral infarction in a southern Han population

    Directory of Open Access Journals (Sweden)

    Song YM

    2014-12-01

    Full Text Available Yanmin Song, Qunfang Li, Lili Long, Ning Zhang, Yunhai Liu Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan Province, People’s Republic of China Background: CD31, also called platelet endothelial cell adhesion molecule-1 (PECAM-1, is thought to play a role in the pathological mechanisms of atherosclerosis. Leu125Val polymorphism and elevated plasma levels of soluble PECAM-1 (sPECAM-1 were found to be associated with cerebral infarction. Our aim was to investigate the association between the Asn563Ser polymorphism of CD31/PECAM-1, plasma level of sPECAM-1, and the risk of atherosclerotic cerebral infarction (ACI in the southern Han population of the People’s Republic of China.Subjects and methods: A total of 147 subjects with ACI and 114 controls were enrolled in the study. The Asn563Ser CD31/PECAM-1 polymorphism was detected using the polymerase chain reaction–restriction fragment length polymorphism method. The plasma spECAM-1 level was measured using the enzyme-linked immunosorbent assay method.Results: In this study, statistically significant differences in Asn563Ser genotype and allele distribution were found between the cases and controls (P<0.05. Furthermore, logistic regression analysis showed that the GG genotype is associated with increase in ACI risk (odds ratio =4.862, P<0.001. The plasma level of sPECAM-1 was associated with ACI (odds ratio =1.431, P=0.038. In both the ACI and the control groups, the plasma sPECAM-1 level in subjects with the GG genotype was higher than that in subjects carrying the AA or GA genotype (P<0.05.Conclusion: Our study showed that the Asn563Ser polymorphism of CD31/PECAM-1 gene and elevated plasma sPECAM-1 level are related to ACI risk in the southern Han population of People’s Republic of China. Keywords: genetic polymorphism, CD31, platelet endothelial cell adhesion molecule-1 (PECAM-1

  15. A New Ala-122-Asn Amino Acid Change Confers Decreased Fitness to ALS-Resistant Echinochloa crus-galli

    Directory of Open Access Journals (Sweden)

    Silvia Panozzo

    2017-11-01

    Full Text Available Gene mutations conferring herbicide resistance may cause pleiotropic effects on plant fitness. Knowledge of these effects is important for managing the evolution of herbicide-resistant weeds. An Echinochloa crus-galli population resistant to acetolactate synthase (ALS herbicides was collected in a maize field in north-eastern Italy and the cross-resistance pattern, resistance mechanism and fitness costs associated to mutant-resistant plants under field conditions in the presence or absence of intra-specific competition were determined. The study reports for the first time the Ala-122-Asn amino-acid change in the ALS gene that confers high levels of cross-resistance to all ALS inhibitors tested. Results of 3-year growth analysis showed that mutant resistant E. crus-galli plants had a delayed development in comparison with susceptible plants and this was registered in both competitive (3, 7, and 20 plants m-2 and non-competitive (spaced plants situations. The number of panicles produced by resistant plants was also lower (about 40% fewer panicles than susceptible plants under no-intraspecific competition. Instead, with the increasing competition level, the difference in panicle production at harvest time decreased until it became negligible at 20 plants m-2. Evaluation of total dry biomass as well as biomass allocation in vegetative parts did not highlight any difference between resistant and susceptible plants. Instead, panicle dry weight was higher in susceptible plants indicating that they allocated more biomass than resistant ones to the reproductive organs, especially in no-competition and in competition situations at lower plant densities. The different fitness between resistant and susceptible phenotypes suggests that keeping the infestation density as low as possible can increase the reproduction success of the susceptible phenotype and therefore contribute to lowering the ratio between resistant and susceptible alleles. If adequately

  16. A New Ala-122-Asn Amino Acid Change Confers Decreased Fitness to ALS-Resistant Echinochloa crus-galli.

    Science.gov (United States)

    Panozzo, Silvia; Scarabel, Laura; Rosan, Valentina; Sattin, Maurizio

    2017-01-01

    Gene mutations conferring herbicide resistance may cause pleiotropic effects on plant fitness. Knowledge of these effects is important for managing the evolution of herbicide-resistant weeds. An Echinochloa crus-galli population resistant to acetolactate synthase (ALS) herbicides was collected in a maize field in north-eastern Italy and the cross-resistance pattern, resistance mechanism and fitness costs associated to mutant-resistant plants under field conditions in the presence or absence of intra-specific competition were determined. The study reports for the first time the Ala-122-Asn amino-acid change in the ALS gene that confers high levels of cross-resistance to all ALS inhibitors tested. Results of 3-year growth analysis showed that mutant resistant E. crus-galli plants had a delayed development in comparison with susceptible plants and this was registered in both competitive (3, 7, and 20 plants m -2 ) and non-competitive (spaced plants) situations. The number of panicles produced by resistant plants was also lower (about 40% fewer panicles) than susceptible plants under no-intraspecific competition. Instead, with the increasing competition level, the difference in panicle production at harvest time decreased until it became negligible at 20 plants m -2 . Evaluation of total dry biomass as well as biomass allocation in vegetative parts did not highlight any difference between resistant and susceptible plants. Instead, panicle dry weight was higher in susceptible plants indicating that they allocated more biomass than resistant ones to the reproductive organs, especially in no-competition and in competition situations at lower plant densities. The different fitness between resistant and susceptible phenotypes suggests that keeping the infestation density as low as possible can increase the reproduction success of the susceptible phenotype and therefore contribute to lowering the ratio between resistant and susceptible alleles. If adequately embedded in a

  17. Probing the diphosphoglycerate binding pocket of HbA and HbPresbyterian (beta 108Asn --> Lys).

    Science.gov (United States)

    Gottfried, D S; Manjula, B N; Malavalli, A; Acharya, A S; Friedman, J M

    1999-08-31

    HbPresbyterian (beta 108Asn --> Lys, HbP) contains an additional positive charge (per alpha beta dimer) in the middle of the central cavity and exhibits a lower oxygen affinity than wild-type HbA in the presence of chloride. However, very little is known about the molecular origins of its altered functional properties. In this study, we have focused on the beta beta cleft of the Hb tetramer. Recently, we developed an approach for quantifying the ligand binding affinity to the beta-end of the Hb central cavity using fluorescent analogues of the natural allosteric effector 2, 3-diphosphoglycerate (DPG) [Gottfried, D. S., et al. (1997) J. Biol. Chem. 272, 1571-1578]. Time-correlated single-photon counting fluorescence lifetime studies were used to assess the binding of pyrenetetrasulfonate to both HbA and HbP in the deoxy and CO ligation states under acidic and neutral pH conditions. Both the native and mutant proteins bind the probe at a weak binding site and a strong binding site; in all cases, the binding to HbP was stronger than to HbA. The most striking finding was that for HbA the binding affinity varies as follows: deoxy (pH 6.35) > deoxy (pH 7.20) > CO (pH 6.35); however, the binding to HbP is independent of ligation or pH. The mutant oxy protein also hydrolyzes p-nitrophenyl acetate, through a reversible acyl-imidazole pathway linked to the His residues of the beta beta cleft, at a considerably higher rate than does HbA. This implies a perturbation of the microenvironment of these residues at the DPG binding pocket. Structural consequences due to the presence of the new positive charge in the middle of the central cavity have been transmitted to the beta beta cleft of the protein, even in its liganded conformation. This is consistent with a newly described quaternary state (B) for liganded HbPresbyterian and an associated change in the allosteric control mechanism.

  18. Some aspects of the nuclear fission process; Quelques aspects du processus de fission nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Netter, F [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1961-07-01

    In the following report one can find first a short general view on the present situation of our knowledge concerning the nuclear fission process, namely on the nucleus going through the saddle-point. Then there are some aspects connected with the excitation energy of the fissioning nucleus. The measurements made at Saclay on the fast neutron fission cross-section of U{sup 233}, U{sup 235}, Pu{sup 239}, U{sup 238} are described at the beginning of this work. It appears that for U{sup 233} there is some characteristic shape modulation of the cross-section curve, in relation with the collective excited state of the deformed nucleus at the saddle-point. Good evidence of this is also given by the study of the relative fission rate with emission of long-range particles; it appears also that this ternary fission rate does not change substantially for neutron between thermal energy and 2 MeV, but that is very lower for the compound nucleus U{sup 239} than for even-even compound nuclei. At the end there are some experiments on the strong 4,5 MeV gamma-ray originated by slow neutron absorption in U{sup 235}. Time-of-flight device is used to establish that this 4,5 MeV gamma-ray seems mostly connected with radiative capture. (author) [French] Le present travail debute par un apercu de l'etat actuel de nos connaissances sur le processus de fission nucleaire, notamment sur le passage par le point-seuil. Puis sont evoques des aspects lies au niveau d'energie d'excitation auquel est porte le noyau qui subit la fission. Les mesures de sections efficaces de fission induite dans {sup 233}U, {sup 235}U, {sup 239}Pu et {sup 238}U par des neutrons rapides effectuees a Saclay sont decrites en premier lieu; elles font apparaitre pour {sup 233}U une ondulation caracteristique du role des etats collectifs d'excitation du noyau deforme au point-seuil. Des experiences sur la fission avec emission de particules de long parcours confirment cet aspect tout en demontrant que la frequence

  19. Cooperation in the Event of Nuclear Accidents; Cooperation en Matiere d'Accidents Nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Bresson, G. [CEA, Centre d' etudes nucleaires, de Fontenay-aux-Roses (France)

    1969-10-15

    This paper is concerned only with the action to be taken in respect of an individual directly affected by an accident and not with the more general measures relating to the population as a whole. Keeping the same sequence of ideas, the paper deals with nuclear establishments and cites criteria for classifying them; hence only the relationship between the establishment and the hospital, and between the radiation protection experts and medical personnel, is discussed. The complex organization of emergency measures, reception of the victim of the accident, and the treatment possibly required should be based on standard practice and published material, both national and international, allowance being made for the characteristics of each sector. A ''flexible'' plan of co-ordination is given as an illustration. Action must be taken in such cases at the site of the accident, inside and outside the establishment, and above all at the hospital. All categories of persons are involved in the process, i.e. fellow-workers, management, specialized services, and medical personnel, each with their own part to play. The manpower and equipment brought into service therefore vary, and depend upon the internal and external relations maintained by the establishment. The measures envisaged should provide for the transport, reception and treatment of those involved in the accident. An existing organization of this kind is described as an illustration. Finally, no action can be of value without full knowledge of the facts and thorough training of the personnel. Some clearly defined ideas on the.subject are considered under this heading. (author) [French] Le memoire ne traite que de la conduite a tenir envers un accidente et non du probleme, plus general, des mesures relatives a une population. Dans le meme ordre d'idees, l'etude porte sur les etablissements nucleaires et leurs criteres de classement; il ne s'agit donc que des liaisons entre retablissement et l'hopital et entre les

  20. Nuclear developments at the international inter govern mental level (1961); Developpements nucleaires sur le plan international intergouvernemental (1961)

    Energy Technology Data Exchange (ETDEWEB)

    Waynbaum, M [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1961-07-01

    The United Nations organisation and nuclear energy rose simultaneously, in 1945, to occupy an important place in the public eye. The spiritual succession of the League of Nations which had foundered during the war was taken up by the new organisation which sought to implant its political ideal in a more tangible reality, so that it might thereby be inspired by concrete and substantial objectives. This is one of the reasons for the existence of the dozen specialized agencies created by the family of the United Nations and dealing with Health, Culture, Agriculture, Finance, etc. Nuclear energy is one of these techniques. Becoming suddenly an important power factor and exploiting for itself the prestige of Science, it became the favorite domain for the growth of this new spirit, as much in its universal form in 1945 as in its more regional form which it was later to adopt. The achievements are numerous and of varying importance; they deserve te be studied carefully. (author) [French] L'organisation des Nations Unies et le nucleaire ont ete places simultanement, en 1945, au premier plan de la scene mondiale. La Societe des Nations ayant sombre pendant la guerre, son heritage spirituel fut recueilli par la nouvelle organisation qui chercha a enraciner son ideal politique dans une realite plus materielle, de facon a y puiser une nourriture concrete et substantielle. C'est une des raisons d'existence de la douzaine d'institutions specialisees gravitant dans la famille des Nations Unies et s'occupant de Sante, de Culture, d'Agriculture, de Finances, etc. Le nucleaire est l'une de ces techniques. Devenu soudainement un facteur primordial de puissance, Cristallisant a son benefice le prestige de la Science, c'etait un terrain de predilection pour le developpement du nouvel esprit, aussi bien sous la forme universelle de 1945, que sous les formes regionales qui ont vu le jour ensuite. Les travaux realises que nombreux, d'importance tres inegale. Ils meritent qu'on les examine

  1. Nuclear developments at the international inter govern mental level (1961); Developpements nucleaires sur le plan international intergouvernemental (1961)

    Energy Technology Data Exchange (ETDEWEB)

    Waynbaum, M. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1961-07-01

    The United Nations organisation and nuclear energy rose simultaneously, in 1945, to occupy an important place in the public eye. The spiritual succession of the League of Nations which had foundered during the war was taken up by the new organisation which sought to implant its political ideal in a more tangible reality, so that it might thereby be inspired by concrete and substantial objectives. This is one of the reasons for the existence of the dozen specialized agencies created by the family of the United Nations and dealing with Health, Culture, Agriculture, Finance, etc. Nuclear energy is one of these techniques. Becoming suddenly an important power factor and exploiting for itself the prestige of Science, it became the favorite domain for the growth of this new spirit, as much in its universal form in 1945 as in its more regional form which it was later to adopt. The achievements are numerous and of varying importance; they deserve te be studied carefully. (author) [French] L'organisation des Nations Unies et le nucleaire ont ete places simultanement, en 1945, au premier plan de la scene mondiale. La Societe des Nations ayant sombre pendant la guerre, son heritage spirituel fut recueilli par la nouvelle organisation qui chercha a enraciner son ideal politique dans une realite plus materielle, de facon a y puiser une nourriture concrete et substantielle. C'est une des raisons d'existence de la douzaine d'institutions specialisees gravitant dans la famille des Nations Unies et s'occupant de Sante, de Culture, d'Agriculture, de Finances, etc. Le nucleaire est l'une de ces techniques. Devenu soudainement un facteur primordial de puissance, Cristallisant a son benefice le prestige de la Science, c'etait un terrain de predilection pour le developpement du nouvel esprit, aussi bien sous la forme universelle de 1945, que sous les formes regionales qui ont vu le jour ensuite. Les travaux realises que nombreux, d

  2. Progress report: nuclear safety and radiation protection in 2006; Rapport annuel: la surete nucleaire et la radioprotection en France en 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    For the French Nuclear Safety Authority (Asn), the year 2006 was marked by two important nuclear laws being passed, one of which brought about a major change in its status. The year was a relatively satisfactory one with regard to nuclear safety, although the picture was more contrasted concerning radiation protection: in this area, more particularly in the medical field, the overall impression of good progress is offset by the declaration of a number of radiotherapy accidents. Given the benefits expected from radiotherapy treatment by the patient suffering from cancer, the conditions in which this activity is carried out are a subject of major concern for Asn, in the light of the serious risks linked to patient over-exposure. ( some important points as follows: the law on transparency and security in the nuclear field, the law on sustainable management of radioactive materials and waste, Asn: an independent administrative authority, EPR reactor project safety, I.R.R.S.: an international audit of Asn in 2006, harmonization of nuclear safety, cancer radiotherapy, improved information of the public after the T.S.N. law, taking account of organisational and human factors). (N.C.)

  3. The national plan of radioactive materials and wastes management. ASN's notice about the choice of the sites to be investigated in view of the setting up of a disposal facility for low activity/long living wastes

    International Nuclear Information System (INIS)

    2009-07-01

    This short presentation, given by the national safety authority (ASN) at the meeting of July 1, 2009 of the high committee for the nuclear safety transparency and information (HCTISN), presents, first, the second French national plan of radioactive materials and wastes management (PNGMDR) with its main priorities, and then, the choice of the sites to survey in view of the setting up of a disposal facility for low level/long living wastes. The ASN expresses its opinion about the criteria retained by the ANDRA (the national agency of radioactive waste management) to select the most suitable sites. (J.S.)

  4. The atomic energy course of the 'Institut National des Sciences et Techniques nucleaires' at the centre d'Etudes Nucleaires at Saclay; L'enseignement de genie atomique de l'Institut national des Sciences et Techniques nucleaires au Centre d'Etudes nucleaires de Saclay

    Energy Technology Data Exchange (ETDEWEB)

    Baissas, H [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    foreign students. 8- Annexe: list of courses, practical work, pile projects drawn up by the 1957 students. (author)Fren. [French] 1- Les raisons de sa creation. L'electricite de France et l'industrie interessee par le developpement de l'Energie atomique ont demande au Commissariat a l'Energie atomique de former des ingenieurs capables d'etudier des projets de piles et de diriger leur construction. 2- Recrutement et Droits d'inscription. Les demandes d'inscription ont toujours depasse les possibilites. Cette annee, les cours sont suivis par 74 eleves permanents, dont 20 etrangers, et une centaine d'auditeurs libres. Tous les elevont deja ingenieurs ou nantis de grades universitaires eleves. Droit d'inscription: 250 000 F pour les eleves, 125 000 F pour les auditeurs. 3- Organisation de l'Enseignement. II comprend deux options: physique et chimie et dans chaque option: une centaine de conferences, une trentaine de travaux pratiques, des stages dans les services, l'etude d'un projet de reacteur par un groupe de 4 ou 5 eleves. L'ensemble occupe l'annee universitaire du 1 novembre au 14 juillet. 4- Sanction. Un examen final combinant les notes de deux epreuves theoriques, des travaux pratiques, du stage, et du projet conduit a un diplome d'ingenieur en genie atomique. Il n'est pas cree en realite de nouveaux ingenieurs; une mention nouvelle est seulement ajoutee a un diplome deja acquis. Les resultats ont toujours ete excellents. Le pourcentage des echecs est tres faible. 5- Placement des Diplomes. Ils reviennent tous dans leurs industries d'origine qui ont paye leurs salaires et les droits d'inscription en se privant de leurs services pendant les neuf mois de duree des cours. 6- Creations analogues. Un cours analogue a ete cree au Centre d'Etudes Nucleaires de Grenoble. Tandis que celui de SACLAY s'adresse plus specialement aux ingenieurs deja en fonctions, celui de Grenoble est, en principe, destine aux jeunes ingenieurs sortant des ecoles. 7- Conclusion. L

  5. Nuclear purity and the production of uranium (1962); La purete nucleaire et la fabrication de l'uranium (1962)

    Energy Technology Data Exchange (ETDEWEB)

    Verte, P [Commissariat a l' Energie Atomique, Centre du Bouchet, Saclay (France). Centre d' Etudes Nucleaires

    1962-07-01

    When the production of 'nuclear grade' uranium is dealt with, it is difficult, the author of this study points out, to separate its chemical, technical, and economical bearings. While recalling the evolution of chemical processes in various countries and describing the technic of uranium manufacture in the plant of the French 'Commissariat a l'Energie Atomique' at Le Bouchet, the author outlines the effect of economical contingencies on the problems the chemists and engineer are faced with. The question of cost price is also considered here with particular attention. (author) [French] Lorsqu'il s'agit de la production d'uranium de 'qualite nucleaire', il est difficile, souligne l'auteur de cette etude, de separer les aspects chimique, technique et economique. Aussi, en retracant l'evolution des procedes chimiques dans divers pays et decrivant les techniques de fabrication de l'uranium a l'usine du Bouchet du Commissariat a l'Energie Atomique, l'auteur ne manque-t-il pas de rappeler les incidences de la conjoncture economique sur les problemes posees au chimiste et a l'ingenieur. La question du prix de revient, egalement, est traitee ici avec une attention particuliere. (auteur)

  6. Public debate about the EPR nuclear power plant at Flamanville; Debat public sur la centrale nucleaire EPR a Flamanville

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    The project of building of he EPR reactor at Flamanville (Manche, France) has been submitted to the public debate. This document includes a presentation of the project and of the rules of the public debate, a synthesis of the file made by the prime contractor (EDF), a synthesis of the collective book of national actors concerned by the project (a group of associations for environment protection, Areva company, the ministries of economy and ecology, Global Chance, association of pro-nuclear ecologists (AEPN), 'Sortir du Nucleaire' (out-of nuclear) network, group of scientists for the information about nuclear (GSIEN), association for the promotion of the Flamanville site (Proflam), French nuclear energy society (SFEN) in association with 'Sauvons le Climat' (let's save climate), regional collective association 'EPR non merci, ni ailleurs, ni ici' (EPR, no thanks, neither elsewhere, nor here), NegaWatt), and 5 detailed books of actors: ACRO (association for the control of radioactivity in Western France), CFDT and CGT syndicates, the economic and social council of Basse Normandie region, and Proflam. (J.S.)

  7. French achievements in the field of nuclear electronics; Realisations francaises dans le domaine de l'electronique nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Doireau, M; Fabre, R; Guillon, H; Guyot, C [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    Nuclear electronic equipment used by the french Atomic Energy Commission has been developed, with an increasing participation of the radioelectric industry (manufacture under AEC license, contracts for prototypes). The equipment for general use has been standardized and satis the technical specification sheets in which are specified more particularly, the conditions for construction, the choice of the spare parts and the conditions for acceptance by the french AEC at factory. The electronic equipment is classified in nine classes, and a brief description of the principal instruments is given in each class. The reliability of the equipment in use is satisfactory, as it is shown by the mean frequency of faults per 1000 hours operation. (author)Fren. [French] L'appareillage d'electronique nucleaire utilise au Commissariat a l'Energie atomique fran is a ete developpe en demandant un concours de plus en plus important a l'industrie radioelectrique (fabrications sous licence CEA, marches de prototypes, etc...). Le materiel d'emploi courant a ete standardise et repond aux specifications de cahiers des charges ou sont precises en particulier les conditions de realisation du materiel, le choix des pieces detachees et les conditions de recette en usine. L'appareillage electronique est classe en neuf rubriques et une description sommaire des principaux appareils est donnee dans chacune des rubriques. La tenue en service du materiel est satisfaisante, ainsi que le montre la frequence moyenne des pannes observees par 1000 heures de fonctionnement. (auteur)

  8. The dangers of irradiate uranium in nuclear reactors; Les dangers de l'uranium irradie dans les reacteurs nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Jammet, H; Joffre, H [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1955-07-01

    The danger of the uranium cans sur-activated by the use in the nuclear reactors is triple: - Irradiation from afar, during manipulations of the cans. - Contamination of air when decladding. - Contamination of air by fire of uranium in a reactor in function The first two dangers are usual and can be treated thanks to the rules of security in use in the atomic industry. The third has an accidental character and claimed for the use of special and exceptional rules, overflowing the industrial setting, to reach the surrounding populations. (authors) [French] Le danger des cartouches d'uranium suractive par utilisation dans les reacteurs nucleaires est triple: - Irradiation a distance, lors des manipulations des cartouches. - Contamination de l'air au moment de leur degainage. - Contamination de l'air par incendie d'uranium dans un reacteur en fonctionnement. Les deux premiers dangers sont habituels et peuvent etre traites grace aux regles de securite en usage dans l'industrie atomique. Le troisieme revet un caractere accidentel et reclame l'emploi de regles speciales et exceptionnelles, debordant le cadre industriel, pour atteindre celui des populations environnantes. (auteurs)

  9. Public debate about the EPR nuclear power plant at Flamanville; Debat public sur la centrale nucleaire EPR a Flamanville

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    The project of building of he EPR reactor at Flamanville (Manche, France) has been submitted to the public debate. This document includes a presentation of the project and of the rules of the public debate, a synthesis of the file made by the prime contractor (EDF), a synthesis of the collective book of national actors concerned by the project (a group of associations for environment protection, Areva company, the ministries of economy and ecology, Global Chance, association of pro-nuclear ecologists (AEPN), 'Sortir du Nucleaire' (out-of nuclear) network, group of scientists for the information about nuclear (GSIEN), association for the promotion of the Flamanville site (Proflam), French nuclear energy society (SFEN) in association with 'Sauvons le Climat' (let's save climate), regional collective association 'EPR non merci, ni ailleurs, ni ici' (EPR, no thanks, neither elsewhere, nor here), NegaWatt), and 5 detailed books of actors: ACRO (association for the control of radioactivity in Western France), CFDT and CGT syndicates, the economic and social council of Basse Normandie region, and Proflam. (J.S.)

  10. Regulation Mechanism of the ald Gene Encoding Alanine Dehydrogenase in Mycobacterium smegmatis and Mycobacterium tuberculosis by the Lrp/AsnC Family Regulator AldR.

    Science.gov (United States)

    Jeong, Ji-A; Hyun, Jaekyung; Oh, Jeong-Il

    2015-10-01

    In the presence of alanine, AldR, which belongs to the Lrp/AsnC family of transcriptional regulators and regulates ald encoding alanine dehydrogenase in Mycobacterium smegmatis, changes its quaternary structure from a homodimer to an octamer with an open-ring conformation. Four AldR-binding sites (O2, O1, O4, and O3) with a consensus sequence of GA/T-N2-NWW/WWN-N2-A/TC were identified upstream of the M. smegmatis ald gene by means of DNase I footprinting analysis. O2, O1, and O4 are required for the induction of ald expression by alanine, while O3 is directly involved in the repression of ald expression. In addition to O3, both O1 and O4 are also necessary for full repression of ald expression in the absence of alanine, due to cooperative binding of AldR dimers to O1, O4, and O3. Binding of a molecule of the AldR octamer to the ald control region was demonstrated to require two AldR-binding sites separated by three helical turns between their centers and one additional binding site that is in phase with the two AldR-binding sites. The cooperative binding of AldR dimers to DNA requires three AldR-binding sites that are aligned with a periodicity of three helical turns. The aldR gene is negatively autoregulated independently of alanine. Comparative analysis of ald expression of M. smegmatis and Mycobacterium tuberculosis in conjunction with sequence analysis of both ald control regions led us to suggest that the expression of the ald genes in both mycobacterial species is regulated by the same mechanism. In mycobacteria, alanine dehydrogenase (Ald) is the enzyme required both to utilize alanine as a nitrogen source and to grow under hypoxic conditions by maintaining the redox state of the NADH/NAD(+) pool. Expression of the ald gene was reported to be regulated by the AldR regulator that belongs to the Lrp/AsnC (feast/famine) family, but the underlying mechanism was unknown. This study revealed the regulation mechanism of ald in Mycobacterium smegmatis and

  11. Improving radiotherapy quality and safety: a common objective of A.S.N. and the Ile de France Regional Hospital Agency. Thoughts on successful cooperation in Ile de France

    International Nuclear Information System (INIS)

    Solier, N.

    2009-01-01

    Radiotherapy recent development in cancer treatment needs strong procedures and quality assessment to improve safety both for patients and professionals. In Ile de France territory, a coordinated action between ASN inspectors and medical doctors specialized in public health (MISP), working as civil servants in health administration, was initiated at the end of 2007. An inspection guideline was implemented in a workshop between ASN and Regional Hospital Agency (ARH). The MISP as health administrator has to verify if care organisation responds to treatment cancer regulatory framework: as a doctor he is authorized to access to patient records to know which treatment was chosen. He has to assure if the therapeutic guidelines are respected. His comprehensive approach is essentially patient-oriented. The MISP inspection coordinated with ASN inspectors is a very pertinent pluri-disciplinary approach, undeniably necessary in such a medical technic. The effectiveness of the radiotherapy pluri-disciplinary team is funded on sharing procedures and experiences, respecting different knowledge and practices in daily work. This on site audit'. seems to be very fertile both for the radiotherapy team, the MISP and ASN inspectors. Continuous quality improvement in radiotherapy in the Ile de France region is a fertile issue between ANS and ARH teams. Confronting knowledge and procedures during the 'on site audit' in a transparent way will contribute improving radiotherapy for the 30.000 Francilian patients which receive this treatment each year. This challenge is our main concern to facilitate the patients access to the best standards treatments. (author)

  12. Hematological and Molecular Characterization of Hb J-Buda [α61(E10)Lys → Asn, AAG > AAT].

    Science.gov (United States)

    Panyasai, Sitthichai; Permsripong, Nopphadol; Jaiping, Kanokwan; Khantarag, Pisuttinee; Pornprasert, Sakorn

    2016-06-01

    Hemoglobin (Hb) J-Buda [α61(E10)Lys → Asn, AAG > AAT] is a very rare α-chain variant found in South-East Asia. We analyzed hematological parameters and provided a rapid molecular analysis method for detection of this hemoglobinopathy in two Thai women who had severe microcytic anemia with Hb and MCV AAG → AAT mutation at codon 61 for Hb J-Buda on one allele of the α1-globin gene. The developed Allele-specific PCR (ASPCR) showed the 455 bp amplified fragment from Hb J-Buda allele. Thus, understanding of hematological characterizations and the developed ASPCR for diagnosis of Hb J-Buda are essential for genetic counseling of this hemoglobinopathy.

  13. Substrate recognition and catalysis by GH47 α-mannosidases involved in Asn-linked glycan maturation in the mammalian secretory pathway

    Energy Technology Data Exchange (ETDEWEB)

    Xiang, Yong; Karaveg, Khanita; Moremen, Kelley W.

    2016-11-17

    Asn-linked glycosylation of newly synthesized polypeptides occurs in the endoplasmic reticulum of eukaryotic cells. Glycan structures are trimmed and remodeled as they transit the secretory pathway, and processing intermediates play various roles as ligands for folding chaperones and signals for quality control and intracellular transport. Key steps for the generation of these trimmed intermediates are catalyzed by glycoside hydrolase family 47 (GH47) α-mannosidases that selectively cleave α1,2-linked mannose residues. Despite the sequence and structural similarities among the GH47 enzymes, the molecular basis for residue-specific cleavage remains obscure. The present studies reveal enzyme–substrate complex structures for two related GH47 α-mannosidases and provide insights into how these enzymes recognize the same substrates differently and catalyze the complementary glycan trimming reactions necessary for glycan maturation.

  14. Control of doses delivered to patients in medical imagery. Progress report of the program of actions recommended by the ASN. January 2015

    International Nuclear Information System (INIS)

    2015-01-01

    This report proposes an overview and an assessment of the various actions recommended by the ASN (the French Nuclear Safety Authority) for a better management of doses delivered to patients in the case of medical imagery. It indicates and discusses the progress noticed: actions which have been already performed, actions which are currently in progress, and actions which are still to be launched. These actions concern various aspects: the practice quality and safety (quality and safety management), the organisation, human resources and training, equipment and installation safety, radio-vigilance practices, relationships with patients, knowledge of practices and of exposures of patients and workers. Some highlights are outlined: some persistent lacks in human resources, some encouraging initiatives in the field of training, some progresses in the field of practice quality and safety, and some limited results regarding equipment (notably MRI) and installation safety

  15. Post-Construction Testing of the Elk River, Hallam and Piqua Power Reactor Plants; Essais apres construction des centrales nucleaires d'Elk River, de Hallam et de Piqua; Predehkspluatatsionnoe ispytanie Ehlk-riverskoj, Khehlpemskoj i Pikuaskoj ehnergeticheskikh reaktornykh ustanovok; Ensayos posteriores a la construccion de las centrales nucleoelectricas de Elk River, Hallam y Piqua

    Energy Technology Data Exchange (ETDEWEB)

    Pursel, C. A. [United States Atomic Energy Commission, Argonne, IL (United States)

    1963-10-15

    numerous, observed or suspected, deficiencies or malfunctions of components which led to additional testing and analyses. In some instances, repair or modification of components was necessary to correct fabrication or engineering errors. Major problem areas are discussed: Elk River Reactor. Discovery of cracks in portions of the reactor vessel surface cladding led to extensive investigations and analyses and required some repairs and vessel modifications. Insufficient steam separation capacity required replacement and modification of some reactor vessel internal hardware. Hallam Nuclear Power Facility. Entrainment of the helium cover gas led to modifications of the secondary sodium loops. Failure of a tube in the intermediate (sodium to sodium) heat exchanger led to analyses to determine the cause of failure followed by removal and repair of the heat exchanger. Piqua Nuclear Power Facility. Chemical cleaning of the piping system damaged several valves which required mere repair or replacement. Leaks in the organic coolant and steam tracing systems caused repeated delays. After completion of the necessary repairs and modifications, the actual performance characteristics of each of the three reactors closely matched design predictions. (author) [French] Les resultats des essais apres construction de trois centrales nucleaires, dans le cadre du programme de demonstration des centrales nucleaires de la Commission de l'energie atomique des Etats-Unis (CEA-EU), permettront peut-etre de faire certaines generalisations concernant cette phase de la construction et de l'exploitation des centrales. Ces trois centrales, le reacteur de puissance d'Elk River (ERR), la centrale nucleaire de Hallam (HNPF), et la centrale nucleaire de Piqua (PNPF), appartiennent a trois filieres differentes: reacteur a eau bouillante a circulation naturelle, reacteur a graphite et a sodium et reacteur ralenti et refroidi par un fluide organique. La periode des essais apres construction a commence a la fin

  16. Study of some continuous spectra produced by nuclear reactions with light nuclei; Etude de quelques spectres continus produits par reactions nucleaires avec des noyaux legers

    Energy Technology Data Exchange (ETDEWEB)

    Marquez, L

    1966-07-01

    The continuous spectra coming from several nuclear reactions with light nuclei were measured. The spectra can be explained by a two-step reaction mechanism; however, the reactions produced by {sup 6}Li are different. A mechanism was proposed to explain their spectra based on the following assumptions: {sup 6}Li makes a nuclear molecule with the target which subsequently breaks up in such a way that an {alpha} particle comes out with the kinetic energy that it has in the molecule. The calculated spectra and those measured are in good agreement. (author) [French] Nous avons mesure les spectres continus produits dans plusieurs reactions nucleaires avec des noyaux legers. A l'exception des spectres produits par {sup 6}Li, on a trouve qu'on pouvait expliquer ces spectres par le mecanisme des reactions en deux etapes. Nous avons propose un mecanisme pour expliquer les spectres produits par {sup 6}Li. On suppose que {sup 6}Li forme une molecule nucleaire avec la cible qui eclate ensuite de facon telle qu'une particule alpha de la molecule sort avec l'energie cinetique de son mouvement propre dans la molecule. Les spectres calcules avec ces hypotheses et les spectres mesures sont en bon accord. (auteur)

  17. The nuclear power stations of the French atomic energy programme (1960); Les centrales nucleaires de puissance du programme francais (1960)

    Energy Technology Data Exchange (ETDEWEB)

    Leduc, C [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires; Roux, J P [Electricite de France (EDF), 75 - Paris (France)

    1960-07-01

    After recalling the entry of nuclear energy into energy production in France, the paper emphasizes the evolution of techniques applied in the designing of French nuclear power plants and describes the means employed for reducing costs per kWh of EDF2 and EDF3 compared with EDF1: the electric power per ton of uranium varies from 493 kW/t for EDF1 to 970 kW/t for EDF3. For this purpose the thermal power and electric power of units are changed respectively from 290 MWt for EDF1 to 1200 or 1600 MWt for EDF3 and from 28 to 250 MW. The results are obtained by an improvement in neutronic characteristics, developments in nuclear fuel technology, and simplification of the system of charging the reactor, whose means of maintenance are increased; the EDF2 heat-exchangers have been so designed as to increase the unit power of the elements, which will attain 9 MWt, as against 3 for EDF1. For EDF3 an advance project forecasts a thermodynamic layout with only one pressure stage. The paper ends with a description of the burst-slug detection systems, and an appendix gives a detailed comparative table of EDF1, EDF2 and EDF3 plant characteristics. (author) [French] Apres avoir rappele l'integration de l'energie nucleaire parmi les moyens de production de l'energie en France, les auteurs se penchent surtout sur l'evolution des techniques appliquees dans l'equipement des centrales nucleaires francaises et decrivent les moyens mis en oeuvre pour reduire les prix de revient du kWh d'EDF2 et d'EDF3 par rapport a EDF1: la puissance electrique par tonne d'uranium varie de 493 kW/t pour EDF1 a 970 kW/t pour EDF3. C'est dans ce but que les puissances thermiques et la puissance unitaire des groupes turbo-alternateurs passent respectivement de 290 MWt pour EDF1 a 1200 ou 1600 MWt pour EDF3 et de 82 a 250 MW. Les resultats sont obtenus par une amelioration des caracteristiques neutroniques, des progres realises sur la technologie des elements combustibles, une simplification du systeme de

  18. Optimal sizes and siting of nuclear fuel reprocessing plants; Tailles et localisations optimales des usines de retraitement des combustibles nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Thiriet, L; Deledicq, A [Commissariat a l' Energie Atomique, Siege (France). Centre d' Etudes Nucleaires

    1967-07-01

    The expansion of a nuclear economy entails the development of fuel process and reprocessing plant programmes. The model proposed makes it possible to select the size, the site and the start-up schedule of the plants in such a way as to minimize the total freight and reprocessing costs. As an illustration, we have approached the problem of burnt natural uranium processing plants related to natural uranium-graphite as nuclear power stations. The sites and annual output of the reactors, the possible plant sites and cost functions (freight and reprocessing) are supposed to be known. The method consists in first approaching the process plant problem as a Dynamic Programming problem, increasing programme slices (total reactor output) being explored sequentially. When the quantities of burnt natural uranium to be reprocessed are fixed, the minimization of the transport cost is then also carried out as a dynamic programming problem. The neighbourhood of the optimum process cost is explored in order to find the minimum summation of a suboptimal processing cost and corresponding optimal transport cost. As the reprocessing problem can be represented on a sequential graph, in order to compute the sub-optima, we developed and used a 'reflexion algorithm'. The method can be interpreted as a general mechanism for determining the optimum when to a sequential dynamic problem (for example an equipment programme) is added a complementary problem (transport, for instance). It also makes it possible to estimate the economic losses which result from the choice of a non optimal policy for other than economic reasons. (author) [French] L'expansion de l'economie nucleaire se traduit par un developpement des programmes d'usines d'elaboration et de retraitement des combustibles. Le modele propose permet de choisir la taille, la localisation et la cadence de mise en service des usines de maniere a minimiser le total des frais de transport et de retraitement. A titre d'exemple nous avons

  19. Spectral content of seismic movements produced by underground nuclear explosions; Contenu spectral des mouvements seismiques dus aux explosions nucleaires souterraines

    Energy Technology Data Exchange (ETDEWEB)

    Albaret, A; Duclaux, F [Commissariat a l' Energie Atomique, Bruyeres-le-Chatel (France). Centre d' Etudes

    1969-07-01

    After a summary of available data, both theoretical and experimental, concerning the spectral content of seismic movements, a description is given of the experiments carried out during the French nuclear explosions in the Sahara, and of the results obtained on the volume waves. A comparison is then made with certain American results. A new method is described for studying the amplitude spectra; it has made it possible to show that the amount of low frequencies in the spectrum increases with the power of the explosion, and decreases with the distance to the zero point and with the filtering effect of the weathered zone. A calculation is then made of the low cut-off ground filter, this giving a better representation of the initial seismic phenomenon. (authors) [French] Apres avoir resume les connaissances disponibles, aussi bien theoriques qu'experimentales, sur le contenu spectral des mouvements seismiques, on decrit les experiences effectuees a l'occasion des explosions nucleaires francaises du Sahara et les resultats obtenus sur les ondes de volume. Puis on les compare avec certains resultats americains. On decrit une nouvelle methode d'etude des spectres d'amplitudes qui montre que le spectre est d'autant plus riche en basses frequences que la puissance de l'explosion est grande, que la distance au point zero est faible et qu'il est moins filtre par la zone alteree superficielle. Puis on calcule le filtre terrain coupe-bas qui permet de donner une representation plus fidele du phenomene seismique initial. (auteurs)

  20. Possibilities and limitations of analogue methods for studying the dynamics of nuclear power stations; Possibilites et limitations du calcul analogique pour les etudes dynamiques de centrales nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Caillet, C; Deat, M [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    1. Introduction: the present paper is devoted to analog simulation of problems related to nuclear reactors other than the simulation of the kinetic equations which is well known. 2. Thermodynamic problems: various problems relative to temperature evolution in a reactor, in a pipe, in an exchanger, in a turbine, are studied, and simulation techniques used by earlier authors are critically reviewed. 3. Pipe simulators: it is shown that this problem can be solved by the use of specialized simulators which will be described and analysed. 4. Rotating machine simulators: the particular aspect of rotating machine calculations introducing frequent use of diagrams is emphasized. A simulator requiring both digital and analogue methods is described. 5. The study of a nuclear power station: as an example it is proposed to discuss problems a rising in connection with the preceding elements (a, b, c, d) when simulating the behaviour of large nuclear plants. The part played by ordinary computing elements for the simulation of the different servomechanism transfer functions is considered and process of regulation is outlined. 6. Conclusion: the necessity of the use of high quality simulators and computers is underlined and the accuracy of the solutions is discussed. (author)Fren. [French] 1. Cinetique des reacteurs: la simulation des equations cinetiques d'un reacteur nucleaire ne pose desormais plus de probleme. II est donc possible de faire le point des differentes applications de la technique analogique dans ce domaine. 2. Les problemes thermodynamiques: on discute les differents problemes poses par l'evolution des temperatures dans un reacteur, dans une tuyauterie, dans un echangeur, dans une turbine, et on passe en revue les techniques de simulation proposees jusqu'a ce jour. 3s simulateurs de tuyauteries: on montre comment les differents problemes poses ci-dessus peuvent etre resolus, pour une classe tres vaste de reacteurs par l'emploi de simulateurs speciaux que l

  1. Summary of the report A.S.N. n. 2006 ENSTR 019 - IGAS n. RM 2007-015P on the Epinal radiotherapy accident

    International Nuclear Information System (INIS)

    2007-01-01

    The Nuclear Safety Authority (A.S.N.) and the General Inspection of Social Affairs (I.G.A.S.) have been in charge by the Ministry of an inquiry on the accident that has lead to the overdose of 23 patients irradiated for a prostate cancer at the Hospital of Epinal. This event constitutes the most important accident implying the ionizing radiations occurring in France. In may 2004, the protocol of conformal radiotherapy applied to the prostate cancers has been modified, it uses dynamics corners in place of static corners. This change supposes to modify the parameters definition that gives the calculation of irradiation intensity, that will not not be made for some of patients. This mistake could be changed if the in vivo dosimetry that allows to check the real dose received by the patients had been kept. but this line of safety has been removed, the use of dynamic corners making it ineffective. The period of over irradiation has been from the 6. may 2004 to the 1. august 2005. During the summer 2005, the radiotherapist and radio physicist find the overdose error by examining the patients files again. On the 15. september 2005, the two doctors of the service warn the director of the C.H.J.M. (hospital center of Jean Monnet) of the accident that informs D.D.A.S.S. (departmental direction of sanitary and social affairs) and A.R.H. (regional agencies of hospitalization). But the national authorities (A.F.S.S.A.P.S., A.S.N., I.R.S.N.) have not been warned, and so nobody can recognize the unsuitable character of the decided measures. Only seven patients are informed of the overdose of radiations they received during the last trimester 2005. The assistance to the victims is not organised the first year. All the patients have received usual treatments when they should receive a treatment by graft of mesenchymatous stem cells. Between september 2005 and september 2006 four patients died and ten present serious complications. propositions have been made to help the victims and

  2. Simplified Procedures for Obtaining Clearances of Foods Preserved by Ionizing Energy; Procedures Simplifiees pour Obtenir l'Autorisation de Produire des Denrees Alimentaires Conservees par les Rayonnements Ionisants; Uproshennaya protsedura polucheniya razreshenij na prodazhu obluchennk pishchevykh produktov; Simplificacion de los Procedimientos para la Obtencion de Autorizaciones de Venta de Alimentos Conservados Mediante Radiaciones Ionizantes

    Energy Technology Data Exchange (ETDEWEB)

    Josephson, E. S. [United States Army Natick Laboratories, Natick, MA (United States)

    1966-11-15

    pommes de terre a chair blanche, la comestibilite de ces denrees etant tout a fait satisfaisante. Aux Etats-Unis, pour developper la production de ces denrees dans des proportions suffisantes pour alimenter le marche, il est necessaire d'obtenir l'autorisation du Service de controle des produits alimentaires et pharmaceutiques et, pour les viandes de mammiferes et de volatiles, celle du Departement de l'agriculture. Ces institutions ont approuve la mise sur le marche de lard, de ble et derives et de pommes de terre a chair blanche, apres reception et examen de demandes contenant tous les renseignements pertinents, notamment la description du procede d'irradiation et de conditionnement a faire accepter, la source de rayonnements proposee, la dose, les methodes de dosimetrie, les donnees relatives a la comestibilite et a la valeur nutritive, la preuve positive de l'innocuite microbiologique, l'absence de radioactivite induite mesurable, le certificat d'acceptation d'un groupe de degustateurs et, s'il y a lieu, les donnees relatives a l'emmagasinage et a l'expedition. Le rassemblement des donnees necessaires aux demandes d'autorisation s'est revele a l'usage long et couteux. Pour remedier a cet inconvenient, on etudie actuellement les moyens de simplifier et d'accelerer le rassemblement des donnees et la redaction des demandes. L'auteur presente des recommandations touchant certaines des methodes qui permettraient d'arriver a ce resultat. (author) [Spanish] Despues de trece anos de investigaciones intensivas con aplicacion de elevadas dosis de radiaciones ionizantes se ha logrado prolongar considerablemente en laboratorio el perfodo de conservacion de productos tales como el tocino, el jamon, la carne de cerdo, la carne de vaca, los pollos y los mariscos, sin que pierdan su comestibilidad. Aplicando dosis inferiores al Mrad puede prolongarse el perfodo de conservacion del pescado, del trigo y sus derivados, de las naranjas y de las patatas blancas en condiciones de

  3. Elimination of effluents and wastes contaminated by radionuclides produced in installations authorized on the account of the Public Health Code - ASN guide nr 18 - Release of the 26/01/2012

    International Nuclear Information System (INIS)

    2012-01-01

    This document aims at specifying the modalities of application of a decision taken by the ASN in January 2008 regarding the technical rules which the elimination of effluents and wastes contaminated by radionuclides must comply with. First, it describes the objective of the 'waste zoning' concept. Then, it addresses the management of contaminated wastes: general rules, wastes contaminated by radionuclides of very short period (less than 100 days) and of period longer than 100 days, and the management of wastes with 'hybrid risks'. It addresses the management of contaminated effluents: radioactive liquid effluent with a period either shorter or longer than 100 days, radioactive gaseous effluents. It addresses the warehousing conditions (premise design, exploitation rules). The other parts deal with the convention between several establishments within a same site (notably in the case of nuclear medicine departments), with the management plan, and with the agenda for the implementation of the ASN decision

  4. Corrosion by cooling gases in nuclear reactors; la corrosion par les gaz caloporteurs dans les reacteurs nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Darras, R. [Commissariat a l' energie atomique et aux energies alternatives - CEA, Centre de Saclay, Section d' etude de la corrosion par gaz et metaux liquides (France)

    1960-07-01

    This article begins with a review of the various materials which can be used and the cooling gases in which they may be heated, emphasis being placed on the importance of reaching temperatures as high as possible. This is followed by a few general remarks on the dry oxidation of metals and alloys, particularly with regard to diffusion phenomena and their various possible mechanisms, and also the methods of investigation employed. Finally, the behaviour of the chief nuclear materials heated in the various gases is studied successively. Materials used for fuel (metallic uranium, uranium oxide, carbides and silicides), canning materials (magnesium, aluminium, zirconium, beryllium, stainless and refractory steels), structural materials (ordinary or slightly alloyed steels), and finally moderators (graphite, beryllium oxide) are deal with in this way. This account is backed up both by the results obtained at the CEA and by work published outside or abroad up to the present day. In conclusion, every effort has been made to direct future research on the basis of the foregoing. Reprint of a paper published in Industries Atomiques - no. 9/10, 1959, p. 3-23 [French] Dans cet article, on passe tout d'abord en revue les divers materiaux utilisables et les gaz de refroidissement dans lesquels ils peuvent etre chauffes, en insistant sur l'interet d'atteindre des temperatures aussi elevees que possible. On rappelle ensuite quelques generalites sur l'oxydation seche des metaux et alliages, notamment en ce qui concerne les phenomenes de diffusion et leurs divers mecanismes possibles ainsi que les methodes d'etude. Enfin, le comportement des principaux materiaux nucleaires chauffes dans les divers gaz est etudie successivement. On traita ainsi des materiaux combustibles (uranium metallique, oxyde, carbures et siliciures d'uranium), des materiaux de gainage (magnesium, aluminium, zirconium, beryllium, aciers inoxydables et refractaires), des materiaux de structure (aciers ordinaires

  5. A study of switch circuits for use as safety devices in nuclear reactors; Etude de circuits de commutation destines a la securite des reacteurs nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Hantcherian, V [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1960-12-15

    The author reviews briefly a few basic assemblies using electromagnetic relays for safety circuits in nuclear reactors; he then studies the use of static relays with a shorter time of response, based on impedance changes in a self-inductance consisting of a coil with a magnetic core having a rectangular hysteresis cycle. The author examines in particular the way in which it functions and the method of determining the parameters. (author) [French] L'auteur apres avoir examine sommairement en revue quelques montages de base des circuits de securite des reacteurs nucleaires utilisant des relais electromecaniques, etudie l'emploi des relais statiques a plus grande vitesse de reponse bases sur la variation d'impedance que presente une self-inductance realisee a l'aide d'une bobine enroulee autour d'un noyau magnetique a cycle d'hysteresis rectangulaire. En particulier, il en examine le mode de fonctionnement et la determination des parametres. (auteur)

  6. Description of methods for making activation detectors for use in nuclear reactors; Description des procedes de fabrication des detecteurs d'activation utilises dans les reacteurs nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Barbalat, R; Le Coguie, R; Leger, P; Salon, L; Thierry, M [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1968-07-01

    A brief description of methods currently used for making activation detectors, thin films and various deposits used in nuclear reactors. The thicknesses required vary from about a few tenths of a micron to a few tenths of a millimeter. Different techniques are used for fixing the large variety of elements: rolling, moulding, painting, electrolysis, vacuum deposition, thin films, wires, enamels, protective linings, etc. (authors) [French] Expose succinct des procedes actuellement mis en oeuvre pour la realisation des detecteurs d'activation, feuilles minces et depots divers utilises dans les reacteurs nucleaires. La gamme des epaisseurs necessaires s'etendant approximativement des dixiemes de micrometre aux dixiemes de millimetre. La diversite des elements a fixer justifiant les techniques differentes selon les cas: laminage, moulage, peinture, electrolyse, depot sous vide, couches minces, fils, emaux, revetements protecteurs, etc. (auteurs)

  7. Installation and testing of the 150keV high current pulsed accelerator installed at the Service de Physique Nucleaire in Bruyeres-le-Chatel

    International Nuclear Information System (INIS)

    Dandine, Andre; Sinopoli, Louis.

    1976-01-01

    A 150keV accelerator installed at the Service de Physique Nucleaires in Bruyeres-le-Chatel is described which has been equipped especially for the preparation of the nuclear experiments carried out with the EN 7MV tandem Van de Graaff, and for the completion of totally independent experiments. Details of the ion optical arrangement and the pulsing system are presented; unanalysed beams of intensity 1 to 2mA are obtained accelerating either protons or deuterons. In the pulsed mode, at 1.25 MHz or 2.5MHz, the average intensity of the analysed beam is 8 to 10μA and the pulse length is 2ns [fr

  8. Structure-activity relationships of the unique and potent agouti-related protein (AGRP)-melanocortin chimeric Tyr-c[beta-Asp-His-DPhe-Arg-Trp-Asn-Ala-Phe-Dpr]-Tyr-NH2 peptide template.

    Science.gov (United States)

    Wilczynski, Andrzej; Wilson, Krista R; Scott, Joseph W; Edison, Arthur S; Haskell-Luevano, Carrie

    2005-04-21

    The melanocortin receptor system consists of endogenous agonists, antagonists, G-protein coupled receptors, and auxiliary proteins that are involved in the regulation of complex physiological functions such as energy and weight homeostasis, feeding behavior, inflammation, sexual function, pigmentation, and exocrine gland function. Herein, we report the structure-activity relationship (SAR) of a new chimeric hAGRP-melanocortin agonist peptide template Tyr-c[beta-Asp-His-DPhe-Arg-Trp-Asn-Ala-Phe-Dpr]-Tyr-NH(2) that was characterized using amino acids previously reported in other melanocortin agonist templates. Twenty peptides were examined in this study, and six peptides were selected for (1)H NMR and computer-assisted molecular modeling structural analysis. The most notable results include the identification that modification of the chimeric template at the His position with Pro and Phe resulted in ligands that were nM mouse melanocortin-3 receptor (mMC3R) antagonists and nM mouse melanocortin-4 receptor (mMC4R) agonists. The peptides Tyr-c[beta-Asp-His-DPhe-Ala-Trp-Asn-Ala-Phe-Dpr]-Tyr-NH(2) and Tyr-c[beta-Asp-His-DNal(1')-Arg-Trp-Asn-Ala-Phe-Dpr]-Tyr-NH(2) resulted in 730- and 560-fold, respectively, mMC4R versus mMC3R selective agonists that also possessed nM agonist potency at the mMC1R and mMC5R. Structural studies identified a reverse turn occurring in the His-DPhe-Arg-Trp domain, with subtle differences observed that may account for the differences in melanocortin receptor pharmacology. Specifically, a gamma-turn secondary structure involving the DPhe(4) in the central position of the Tyr-c[beta-Asp-Phe-DPhe-Arg-Trp-Asn-Ala-Phe-Dpr]-Tyr-NH(2) peptide may differentiate the mixed mMC3R antagonist and mMC4R agonist pharmacology.

  9. "Minulost je bitevním polem současníků". Konference k osmdesátinám Viléma Prečana

    Czech Academy of Sciences Publication Activity Database

    Hoppe, Jiří

    2013-01-01

    Roč. 20, 1/2 (2013), s. 236-241 ISSN 1210-7050. ["Minulost je bitevním polem současníků". Konference k osmdesátinám Viléma Prečana. Praha, 24.01.2013-25.01.2013] Institutional support: RVO:68378114 Keywords : Vilém Prečan Subject RIV: AB - History

  10. Celostátní seminář Celoživotní učení - Kroměříž 2006 "Současná realita - budoucnost".

    Czech Academy of Sciences Publication Activity Database

    Basl, Josef

    2006-01-01

    Roč. 10, č. 6 (2006) ISSN 1212-5075. [Celoživotní učení - Kroměříž 2006 "Současná realita - budoucnost". Kroměříž, 18.05.2006-19.05.2006] R&D Projects: GA ČR GA403/06/1421 Institutional research plan: CEZ:AV0Z70280505 Keywords : Czech Republic * lifelong learning * current issues Subject RIV: AO - Sociology, Demography

  11. Antioxidant and antiglycation activities of the synthesised dipeptide, Asn-Trp, derived from computer-aided simulation of yam dioscorin hydrolysis and its analogue, Gln-Trp.

    Science.gov (United States)

    Han, Chuan-Hsiao; Lin, Yin-Shiou; Lin, Shyr-Yi; Hou, Wen-Chi

    2014-03-15

    Previous studies have shown that the Trp residue contributes to a high oxygen radical absorbance capacity (ORAC). Therefore, in this study, a Trp-containing dipeptide derived from a computer-aided simulation of pepsin hydrolysis of the yam tuber, dioscorin-namely, Asn-Trp (NW), and its analogue, Gln-Trp (QW)-were synthesised to compare their antioxidant and antiglycation activities with carnosine, homocarnosine, or glutathione (GSH). The antioxidant assays included hydroxyl radical-scavenging activity, anti-AAPH-induced hemolysis, and ORAC activity. NW had a significantly higher antioxidant activity than had QW and performed much better than carnosine, homocarnosine, or GSH. Using bovine serum albumin (BSA)/galactose or BSA/glucose as experimental models, NW had better antiglycation effects than had QW, as detected by an anti-N(ε)-(carboxymethyl)lysine (anti-CML) antibody. Moreover, NW and QW (50-200 μM) showed protection against methylglyoxal-induced cell deaths in human umbilical vein endothelial cells. These results suggest that NW, derived from computer-aided simulation of dioscorin hydrolysis, exhibits antioxidant and antiglycation activities, which thus shows the benefits of the yam tuber as an antioxidant-rich food. Copyright © 2013 Elsevier Ltd. All rights reserved.

  12. [Hb Burgos (α1 CD64(E13)(Asp→Asn)): a new hemoglobin variant detected during follow-up of diabetic patients].

    Science.gov (United States)

    de la Fuente-Gonzalo, Félix; Martínez Nieto, Jorge; Torrejón, María José; Mayor, Luis Antonio; Velasco, Diego; González Fernández, Fernando Ataulfo; Ropero Gradilla, Paloma

    2015-01-06

    The glycated hemoglobin (HbA1c) test by high performance liquid chromatography is a useful tool for the follow-up of diabetes mellitus patients. Some structural hemoglobin (Hb) variants are known to cause interference in the analytical measurement of HbA1c. In this study, it has been characterized a new Hb variant in 4 patients during their regular control of HbA1c. Selective α1 gene sequencing showed a mutation GAC>AAC at codon 64 within exon 2. This produces a change of aspartic acid (Asp) by asparagine (Asn) that does not produce any functional alteration so the resultant molecule behaves as a silent hemoglobinopathy. The structural Hb variants can be detected during the analysis of HbA1c and may alter its values. Though rare, this occurrence signals the need to being aware when measuring HbA1c. Copyright © 2014 Elsevier España, S.L.U. All rights reserved.

  13. Identification of homozygous WFS1 mutations (p.Asp211Asn, p.Gln486*) causing severe Wolfram syndrome and first report of male fertility.

    Science.gov (United States)

    Haghighi, Amirreza; Haghighi, Alireza; Setoodeh, Aria; Saleh-Gohari, Nasrollah; Astuti, Dewi; Barrett, Timothy G

    2013-03-01

    Wolfram syndrome (WFS) is a neurodegenerative genetic condition characterized by juvenile-onset of diabetes mellitus and optic atrophy. We studied clinical features and the molecular basis of severe WFS (neurodegenerative complications) in two consanguineous families from Iran. A clinical and molecular genetic investigation was performed in the affected and healthy members of two families. The clinical diagnosis of WFS was confirmed by the existence of diabetes mellitus and optic atrophy in the affected patients, who in addition had severe neurodegenerative complications. Sequencing of WFS1 was undertaken in one affected member from each family. Targeted mutations were tested in all members of relevant families. Patients had most of the reported features of WFS. Two affected males in the first family had fathered unaffected children. We identified two homozygous mutations previously reported with apparently milder phenotypes: family 1: c.631G>A (p.Asp211Asn) in exon 5, and family 2: c.1456C>T (p.Gln486*) in exon 8. Heterozygous carriers were unaffected. This is the first report of male Wolfram patients who have successfully fathered children. Surprisingly, they also had almost all the complications associated with WFS. Our report has implications for genetic counseling and family planning advice for other affected families.

  14. The functional polymorphism rs73598374:G>A (p.Asp8Asn) of the ADA gene is associated with telomerase activity and leukocyte telomere length.

    Science.gov (United States)

    Concetti, Fabio; Carpi, Francesco M; Nabissi, Massimo; Picciolini, Matteo; Santoni, Giorgio; Napolioni, Valerio

    2015-02-01

    Recent evidence demonstrated a relevant role of adenosine deaminase (ADA) in replicative senescence of T cells through its capacity to modulate telomerase activity (TA). Herein, we tested the impact of the functional polymorphism ADA rs73598374:G>A (c.22G>A, p.Asp8Asn) on telomere biology, by measuring TA and leukocyte telomere length (LTL) in healthy subjects selected according to rs73598374 genotype. rs73598374-A carriers showed lower TA (P=0.019) and shorter LTL (P=0.003), respectively, compared to G/G carriers. rs73598374-A carriers showed a stronger cross-sectional age reduction of LTL (r=-0.314, P=0.005) compared to G/G carriers (r=-0.243, P=0.022). The reduced ADA activity associated to rs73598374-A variant predisposes those carriers to display higher levels of adenosine compared to G/G carriers. Consequently, it may lead to an accelerated process of replicative senescence, causing a stronger reduction of TA and in turn shorter LTL. In conclusion, the crucial role played by replicative senescence of the immune system in several human diseases and in the aging process underscores the relevance of the present findings and also spurs interest into the possible involvement of rs73598374 in shaping the susceptibility to several age-related diseases.

  15. Protein changes associated with reprotonation of the Schiff base in the photocycle of Asp96-->Asn bacteriorhodopsin. The MN intermediate with unprotonated Schiff base but N-like protein structure

    Science.gov (United States)

    Sasaki, J.; Shichida, Y.; Lanyi, J. K.; Maeda, A.

    1992-01-01

    The difference Fourier transform infrared spectrum for the N intermediate in the photoreaction of the light-adapted form of bacteriorhodopsin can be recorded at pH 10 at 274 K (Pfefferle, J.-M., Maeda, A., Sasaki, J., and Yoshizawa, T. (1991) Biochemistry 30, 6548-6556). Under these conditions, Asp96-->Asn bacteriorhodopsin gives a photoproduct which shows changes in protein structure similar to those observed in N of wild-type bacteriorhodopsin. However, decreased intensity of the chromophore bands and the single absorbance maximum at about 400 nm indicate that the Schiff base is unprotonated, as in the M intermediate. This photoproduct was named MN. At pH 7, where the supply of proton is not as restricted as at pH 10, Asp96-->Asn bacteriorhodopsin yields N with a protonated Schiff base. The Asn96 residue, which cannot deprotonate as Asp96 in wild-type bacteriorhodopsin, is perturbed upon formation of both MN at pH 10 and N at pH 7. We suggest that the reprotonation of the Schiff base is preceded by a large change in the protein structure including perturbation of the residue at position 96.

  16. Purification, crystallization and preliminary X-ray crystallographic analysis of ST1022, a putative member of the Lrp/AsnC family of transcriptional regulators isolated from Sulfolobus tokodaii strain 7

    Energy Technology Data Exchange (ETDEWEB)

    Nakano, Noboru; Kumarevel, Thirumananseri, E-mail: tskvel@spring8.or.jp; Matsunaga, Emiko; Shinkai, Akeo [RIKEN SPring-8 Center, Harima Institute, 1-1-1 Kouto, Sayo, Hyogo 679-5148 (Japan); Kuramitsu, Seiki [RIKEN SPring-8 Center, Harima Institute, 1-1-1 Kouto, Sayo, Hyogo 679-5148 (Japan); Department of Biological Sciences, Graduate School of Science, Osaka University, Tayonaka, Osaka 560-0043 (Japan); Yokoyama, Shigeyuki, E-mail: tskvel@spring8.or.jp [RIKEN SPring-8 Center, Harima Institute, 1-1-1 Kouto, Sayo, Hyogo 679-5148 (Japan); Genomic Sciences Center, Yokohama Institute, RIKEN, 1-7-22 Suehiro-cho, Tsurumi, Yokohama 230-0045 (Japan); Department of Biophysics and Biochemistry, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan)

    2007-11-01

    A putative member of the Lrp/AsnC family of transcriptional regulators, ST1022 from S. tokodaii strain 7, has been purified and crystallized in the absence and presence of the effector l-glutamine. A molecular-replacement solution was found using the FL11 transcriptional regulator from Pyrococcus sp. OT3 as a model and structural refinement is under way. The Lrp/AsnC family of transcriptional regulators, also known as feast/famine transcriptional regulators, are widely distributed among bacteria and archaea. This family of proteins are likely to be involved in cellular metabolism, with exogenous amino acids functioning as effectors. Here, the crystallization and preliminary X-ray diffraction analysis of ST1022, a member of the Lrp/AsnC family of proteins, is reported with and without exogenous glutamine as the effector molecule. The crystals of native ST1022 and of the putative complex belong to the tetragonal space group I422, with unit-cell parameters a = b = 103.771, c = 73.297 Å and a = b = 103.846, c = 73.992 Å, respectively. Preliminary X-ray diffraction data analysis and molecular-replacement solution revealed the presence of one monomer per asymmetric unit.

  17. Purification, crystallization and preliminary X-ray crystallographic analysis of ST1022, a putative member of the Lrp/AsnC family of transcriptional regulators isolated from Sulfolobus tokodaii strain 7

    International Nuclear Information System (INIS)

    Nakano, Noboru; Kumarevel, Thirumananseri; Matsunaga, Emiko; Shinkai, Akeo; Kuramitsu, Seiki; Yokoyama, Shigeyuki

    2007-01-01

    A putative member of the Lrp/AsnC family of transcriptional regulators, ST1022 from S. tokodaii strain 7, has been purified and crystallized in the absence and presence of the effector l-glutamine. A molecular-replacement solution was found using the FL11 transcriptional regulator from Pyrococcus sp. OT3 as a model and structural refinement is under way. The Lrp/AsnC family of transcriptional regulators, also known as feast/famine transcriptional regulators, are widely distributed among bacteria and archaea. This family of proteins are likely to be involved in cellular metabolism, with exogenous amino acids functioning as effectors. Here, the crystallization and preliminary X-ray diffraction analysis of ST1022, a member of the Lrp/AsnC family of proteins, is reported with and without exogenous glutamine as the effector molecule. The crystals of native ST1022 and of the putative complex belong to the tetragonal space group I422, with unit-cell parameters a = b = 103.771, c = 73.297 Å and a = b = 103.846, c = 73.992 Å, respectively. Preliminary X-ray diffraction data analysis and molecular-replacement solution revealed the presence of one monomer per asymmetric unit

  18. Calculation of the shock-wave in the region close to an underground nuclear explosion (method Cades); Calcul de l'onde de choc en zone proche d'une explosion nucleaire souterraine (methode cades)

    Energy Technology Data Exchange (ETDEWEB)

    Supiot, F; Brugies, J [Commissariat a l' Energie Atomique, Bruyeres-le-Chatel (France). Centre d' Etudes

    1969-07-01

    The outline of a method is presented for calculating the characteristics of a shock wave produced by an underground nuclear explosion (pressure, wave velocity, velocity of the medium, energy left in the medium by the shock, etc.). By means of an application to a granitic medium and of a comparison with results obtained during French nuclear explosions, it has been possible to show the good agreement existing between the calculations and the experimental results. The advantages of such a method for studying the industrial applications of underground nuclear explosions are stressed. (authors) [French] On expose les grandes lignes d'une methode de calcul des caracteristiques de l'onde de choc issue d'une explosion nucleaire souterraine (pression, vitesse de l'onde, vitesse du milieu, energie deposee par le choc dans le milieu...). Une application a un milieu granitique et une comparaison aux resultats obtenus au cours d'explosions nucleaires francaises permet de montrer la bonne concordance entre le calcul et les resultats experimentaux. On souligne l'interet d'une telle, methode pour l'etude d'applications industrielles des explosions nucleaires souterraines. (auteurs)

  19. Annual report ''nuclear safety in France''; Le rapport annuel ''la surete nucleaire en France''

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    This document is the 2001 annual report of the French authority of nuclear safety (ASN). It summarizes the highlights of the year 2000 and details the following aspects: the nuclear safety in France, the organization of the control of nuclear safety, the regulation relative to basic nuclear facilities, the control of facilities, the information of the public, the international relations, the organisation of emergencies, the radiation protection, the transport of radioactive materials, the radioactive wastes, the PWR reactors, the experimental reactors and other laboratories and facilities, the nuclear fuel cycle facilities, and the shutdown and dismantling of nuclear facilities. (J.S.)

  20. Identification of a functional enhancer variant within the chronic pancreatitis-associated SPINK1 c.101A>G (p.Asn34Ser)-containing haplotype.

    Science.gov (United States)

    Boulling, Arnaud; Masson, Emmanuelle; Zou, Wen-Bin; Paliwal, Sumit; Wu, Hao; Issarapu, Prachand; Bhaskar, Seema; Génin, Emmanuelle; Cooper, David N; Li, Zhao-Shen; Chandak, Giriraj R; Liao, Zhuan; Chen, Jian-Min; Férec, Claude

    2017-08-01

    The haplotype harboring the SPINK1 c.101A>G (p.Asn34Ser) variant (also known as rs17107315:T>C) represents the most important heritable risk factor for idiopathic chronic pancreatitis identified to date. The causal variant contained within this risk haplotype has however remained stubbornly elusive. Herein, we set out to resolve this enigma by employing a hypothesis-driven approach. First, we searched for variants in strong linkage disequilibrium (LD) with rs17107315:T>C using HaploReg v4.1. Second, we identified two candidate SNPs by visual inspection of sequences spanning all 25 SNPs found to be in LD with rs17107315:T>C, guided by prior knowledge of pancreas-specific transcription factors and their cognate binding sites. Third, employing a novel cis-regulatory module (CRM)-guided approach to further filter the two candidate SNPs yielded a solitary candidate causal variant. Finally, combining data from phylogenetic conservation and chromatin accessibility, cotransfection transactivation experiments, and population genetic studies, we suggest that rs142703147:C>A, which disrupts a PTF1L-binding site within an evolutionarily conserved HNF1A-PTF1L CRM located ∼4 kb upstream of the SPINK1 promoter, contributes to the aforementioned chronic pancreatitis risk haplotype. Further studies are required not only to improve the characterization of this functional SNP but also to identify other functional components that might contribute to this high-risk haplotype. © 2017 Wiley Periodicals, Inc.

  1. The big interview - Fukushima: 'Collectively, the international nuclear security system has failed'; Grand entretien - Fukushima 'Collectivement, le systeme de surete nucleaire international a failli...'

    Energy Technology Data Exchange (ETDEWEB)

    Niel, J.C. [Autorite de surete nucleaire - ASN, 6, place du Colonel Bourgoin, 75012 Paris (France); ASN, 10, Route du Panorama 92266 Fontenay-aux-Roses cedex (France); Seillan, Hubert

    2011-11-15

    In an interview the ASN (the French Nuclear Safety Authority) manager summarizes his professional career, describes the ASN missions and outlines the independence of this institution as it is defined and practically exists, gives his opinion and analysis on the Fukushima accident, evokes the meaning of stress tests, discusses the information obtained through inspections of the French nuclear power plants, evokes the desirable evolutions at the international level, explains why terrorism has not been integrated in the stress test procedure, comments the implications of the European level on French safety studies. Some actors are briefly presented: the CEA, AREVA, EDF, the World association of nuclear operators (WANO)

  2. Special Nuclear Material Control by the Power Reactor Operator; Controle des Matieres Nucleaires Speciales par l'Exploitant d'une Centrale Nucleaire; Spetsial'nyj kontrol' nalichiya yadernykh materialov operatorom ehnergeticheskogo reaktora; Control de Materiales Nucleares Especiales por Parte de Quienes Operan el Reactor de Potencia

    Energy Technology Data Exchange (ETDEWEB)

    Cordin, R. A. [Yankee Atomic Electric Company, Boston, MA (United States)

    1966-02-15

    insurance programme. (author) [French] L'uranium, combustible relativement nouveau et extremement interessant pour la production d'electricite, doit faire l'objet d'un controle tres strict depuis le moment ou l'exploitant de la centrale en devient financierement responsable jusqu'a celui oti, sous forme de combustible partiellement epuise, la matiere est transferee dans une autre installation et oti l'on recupere ce qui reste de sa valeur initiale. La plupart des exploitants de centrales nucleaires dirigeaient des centrales alimentees par des combustibles fossiles avant l'avenement de l'energie nucleaire et ils ont etabli depuis longtemps un controle etendu et efficace de ces combustibles fossiles. L'exploitant d'une centrale nucleaire doit exercer un controle non moins efficace sur les matieres nucleaires speciales utilisees dans son installation. La technique de l'exploitation des centrales nucleaires n'est pas ancienne et, au cours de, son existence relativement breve, les ingenieurs et hommes de science des Etats-Unis ont constamment ameliore les plans des centrales et les methodes d'exploitation afin de reduire les couts et de permettre aux centrales nucleaires de concurrencer les centrales classiques. La gestion des matieres nucleaires doit etre aussi moderne et efficace que possible pour assurer que les progres technologiques grace auxquels les prix on pu etre reduits ne soient pas mis en echec par des insuffisances dans la manipulation du combustible nucleaire et la tenue de la comptabilite des stocks. Pour assurer la gestion des matieres nucleaires, il faut que l'exploitant de la centrale etablisse et tienne a jour une comptabilite complete et detaillee, sans etre necessairement complexe pour autant; en fait, la simplicite est extremement souhaitable. Bien que le combustible nucleaire soit nouveau et qu'il n'ait rien de commun avec les combustibles classiques, aucun secret ne doit s'y attacher. Le controle des matieres nucleaires dans le cadre de la gestion des

  3. Summary of the report A.S.N. n. 2006 ENSTR 019 - IGAS n. RM 2007-015P on the Epinal radiotherapy accident; Resume du rapport ASN n. 2006 ENSTR 019 - IGAS n. RM 2007-015P sur l'accident de radiotherapie d'Epinal

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    The Nuclear Safety Authority (A.S.N.) and the General Inspection of Social Affairs (I.G.A.S.) have been in charge by the Ministry of an inquiry on the accident that has lead to the overdose of 23 patients irradiated for a prostate cancer at the Hospital of Epinal. This event constitutes the most important accident implying the ionizing radiations occurring in France. In may 2004, the protocol of conformal radiotherapy applied to the prostate cancers has been modified, it uses dynamics corners in place of static corners. This change supposes to modify the parameters definition that gives the calculation of irradiation intensity, that will not not be made for some of patients. This mistake could be changed if the in vivo dosimetry that allows to check the real dose received by the patients had been kept. but this line of safety has been removed, the use of dynamic corners making it ineffective. The period of over irradiation has been from the 6. may 2004 to the 1. august 2005. During the summer 2005, the radiotherapist and radio physicist find the overdose error by examining the patients files again. On the 15. september 2005, the two doctors of the service warn the director of the C.H.J.M. (hospital center of Jean Monnet) of the accident that informs D.D.A.S.S. (departmental direction of sanitary and social affairs) and A.R.H. (regional agencies of hospitalization). But the national authorities (A.F.S.S.A.P.S., A.S.N., I.R.S.N.) have not been warned, and so nobody can recognize the unsuitable character of the decided measures. Only seven patients are informed of the overdose of radiations they received during the last trimester 2005. The assistance to the victims is not organised the first year. All the patients have received usual treatments when they should receive a treatment by graft of mesenchymatous stem cells. Between september 2005 and september 2006 four patients died and ten present serious complications. propositions have been made to help the victims and

  4. Health problems raised by the elimination of radioactive wastes and nuclear accidents; Problemes sanitaires poses par l'elimination des dechets radioactifs et par les accidents nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Jammet, H; Mechali, D; Dousset, M [Commissariat a l' Energie Atomique, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

    1964-07-01

    The rapid development of nuclear energy demands an urgent solution to the health problems arising from the discharge into the environment of radioactive residues produced by nuclear installations. - To be able to evaluate the risks run by the population and to fix tolerance limits for waste discharge, it is necessary to possess an exact knowledge of the course taken by the radioelements discharged, from their source until they reach man. The incorporation of radioelements in food cycles is the first risk to take into consideration. The factors involved in all stages of this transmission must be foreseen, whether they concern physical or biological media, because of their continuity and their interdependence. Finally, socio-economic and dietetic data must be collected in order that the risks and tolerance levels estimated are based on concrete and experimental rather than theoretical knowledge. The risk of nuclear accidents in the atomic industry, although very improbable, must be taken into consideration because of the seriousness of their consequences. The health problems arise in the field of professional hygiene on the one hand and in that of public hygiene on the other. In the first field the risk is two-fold and involves irradiation and contamination. The public sphere is reduced essentially to the risk of contamination by radioactive substances accidentally released in the surrounding medium. The health studies to be conducted in this field therefore include research not only on irradiation or contamination therapeutics but also on the transfer of radioelements from the accident site to man, mainly through food cycles, in their physical and in their biological components. Studies of this kind form the basis of decisions in the health field which would have to be taken in the case of an accident. (authors) [French] Le developpement rapide de l'energie nucleaire rend urgente la solution des problemes sanitaires poses par le rejet dans le milieu ambiant des

  5. Relationship between the nuclear resonance of cobalt metal and its ferromagnetic properties; Relations entre la resonance nucleaire du cobalt metallique et ses proprietes ferromagnetiques

    Energy Technology Data Exchange (ETDEWEB)

    Aubrun, J.N. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-05-15

    Theoretical study of nuclear magnetic resonance in ferromagnetic metals shows the near dependence of ferromagnetic properties and unusual feature of this nuclear resonance. This results from a strong interaction between nuclei and magnetic electrons. They excite the nuclei, and, in Bloch walls, submit them to a RF field much stronger than those directly applied. The parameters of the resonance are determined from wall movement and depend consequently of ferromagnetic constants. The theory is enable to provide quantitatively some peculiar effects, specially those of a continuous magnetic field and of temperature. Experimental study was made on cobalt powders, and is in good agreement with theory. However one must take the skin-effect into consideration and accordingly adjust, the theory. This can explain some observed divergences, as well as the influence at particles size and magnetic field over the line shape. Original informations have been obtained about some typical ferromagnetic properties of cobalt, when studying magnetic field effect, and it has been able to apply this method to other ferromagnetic materials. In consideration of the peculiar characteristics of this nuclear resonance, which occurs without external magnetic field and whose line width is large, new models of spectrographs have been realized and have permitted accurate measures of the line shape. The weak intensity of the signals obtained in some cases, has induced the elaboration of an original method of extraction whose theory and practical uses are described here. The whole of this experiment reveals the nuclear resonance as a strong way for the study of ferromagnetism, which is able to detect microscopic phenomenons, not easily accessible by classical methods. (author) [French] L'etude theorique de la resonance magnetique nucleaire dans les metaux ferromagnetiques revele l'etroite liaison entre les proprietes ferromagnetiques et l'aspect inhabituel de cette resonance. Ceci

  6. Relationship between the nuclear resonance of cobalt metal and its ferromagnetic properties; Relations entre la resonance nucleaire du cobalt metallique et ses proprietes ferromagnetiques

    Energy Technology Data Exchange (ETDEWEB)

    Aubrun, J N [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-05-15

    Theoretical study of nuclear magnetic resonance in ferromagnetic metals shows the near dependence of ferromagnetic properties and unusual feature of this nuclear resonance. This results from a strong interaction between nuclei and magnetic electrons. They excite the nuclei, and, in Bloch walls, submit them to a RF field much stronger than those directly applied. The parameters of the resonance are determined from wall movement and depend consequently of ferromagnetic constants. The theory is enable to provide quantitatively some peculiar effects, specially those of a continuous magnetic field and of temperature. Experimental study was made on cobalt powders, and is in good agreement with theory. However one must take the skin-effect into consideration and accordingly adjust, the theory. This can explain some observed divergences, as well as the influence at particles size and magnetic field over the line shape. Original informations have been obtained about some typical ferromagnetic properties of cobalt, when studying magnetic field effect, and it has been able to apply this method to other ferromagnetic materials. In consideration of the peculiar characteristics of this nuclear resonance, which occurs without external magnetic field and whose line width is large, new models of spectrographs have been realized and have permitted accurate measures of the line shape. The weak intensity of the signals obtained in some cases, has induced the elaboration of an original method of extraction whose theory and practical uses are described here. The whole of this experiment reveals the nuclear resonance as a strong way for the study of ferromagnetism, which is able to detect microscopic phenomenons, not easily accessible by classical methods. (author) [French] L'etude theorique de la resonance magnetique nucleaire dans les metaux ferromagnetiques revele l'etroite liaison entre les proprietes ferromagnetiques et l'aspect inhabituel de cette resonance. Ceci resulte du

  7. Development of mercury porosimeter. Application to nuclear graphite studies (1961); Mise au point d'un porosimetre a mercure. Application a l'etude des graphites nucleaires (1961)

    Energy Technology Data Exchange (ETDEWEB)

    Bocquet, M; Genisson, J; Sailleau, J [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1961-07-01

    A mercury porosimeter, model IFP-CEA, has been developed for application to nuclear graphite studies. The apparatus is based on the capillary depression phenomenon. The relationship between the radius of a pore and the pressure at which mercury fills it is pr = -2 {sigma} cos {theta} ( {sigma} is the surface tension, {theta} the angle of contact of the mercury). After some theoretical consideration, the apparatus is described. The mercury pressure is increased step-wise from 0 to 1000 kg/cm{sup 2} thus yielding the complete distribution of pores from 92 {mu} to 75 A. Results are, then presented concerning nuclear graphites which show the evolution of the porous structure under the effect of bitumen impregnation. In general, the volume of the large pores decreases while that of the small pores increases. The structure of impregnated products appears to depend to a certain extent on that of the starting materials. It has also been possible to study other products with this porosimeter; the range of measurements possible is such that it may be used for the study of the majority of porous materials. (authors) [French] Un porosimetre a mercure modele IFP-CEA a ete mis au point en vue de son application a l'etude de graphites nucleaires. Le fonctionnement de l'appareil repose sur le phenomene de depression capillaire. On etablit la relation existant entre le rayon r d'un pore et la pression p pour laquelle le mercure peut y penetrer: pr = -2 {sigma} cos {theta} ( {sigma} tension superficielle, {theta} angle de contact du mercure). Apres quelques considerations theoriques, l'appareil utilise est decrit. Il permet de faire varier par palier la pression du mercure entre 0 et 1000 kg/cm{sup 2} et d'etablir ainsi la distribution complete des rayons de pores compris entre 92 {mu} et 75 A. Les resultats d'une etude faite sur des graphites nucleaires sont alors presentes faisant apparaitre l'evolution de la structure poreuse sous l'effet des impregnations au brai. D'une facon

  8. Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS

    Directory of Open Access Journals (Sweden)

    Wang Bin

    2007-12-01

    Full Text Available Abstract Background CCR5-restricted (R5 human immunodeficiency virus type 1 (HIV-1 variants cause CD4+ T-cell loss in the majority of individuals who progress to AIDS, but mechanisms underlying the pathogenicity of R5 strains are poorly understood. To better understand envelope glycoprotein (Env determinants contributing to pathogenicity of R5 viruses, we characterized 37 full-length R5 Envs from cross-sectional and longitudinal R5 viruses isolated from blood of patients with asymptomatic infection or AIDS, referred to as pre-AIDS (PA and AIDS (A R5 Envs, respectively. Results Compared to PA-R5 Envs, A-R5 Envs had enhanced fusogenicity in quantitative cell-cell fusion assays, and reduced sensitivity to inhibition by the fusion inhibitor T-20. Sequence analysis identified the presence of Asn 362 (N362, a potential N-linked glycosylation site immediately N-terminal to CD4-binding site (CD4bs residues in the C3 region of gp120, more frequently in A-R5 Envs than PA-R5 Envs. N362 was associated with enhanced fusogenicity, faster entry kinetics, and increased sensitivity of Env-pseudotyped reporter viruses to neutralization by the CD4bs-directed Env mAb IgG1b12. Mutagenesis studies showed N362 contributes to enhanced fusogenicity of most A-R5 Envs. Molecular models indicate N362 is located adjacent to the CD4 binding loop of gp120, and suggest N362 may enhance fusogenicity by promoting greater exposure of the CD4bs and/or stabilizing the CD4-bound Env structure. Conclusion Enhanced fusogenicity is a phenotype of the A-R5 Envs studied, which was associated with the presence of N362, enhanced HIV-1 entry kinetics and increased CD4bs exposure in gp120. N362 contributes to fusogenicity of R5 Envs in a strain dependent manner. Our studies suggest enhanced fusogenicity of A-R5 Envs may contribute to CD4+ T-cell loss in subjects who progress to AIDS whilst harbouring R5 HIV-1 variants. N362 may contribute to this effect in some individuals.

  9. Extensive spectroscopic calculations of the 21 Λ-S and 74 Ω states of the AsN molecule including the spin–orbit coupling effect

    International Nuclear Information System (INIS)

    Liu, Hui; Shi, Deheng; Sun, Jinfeng; Zhu, Zunlue

    2015-01-01

    The potential energy curves (PECs) of 74 Ω states generated from the 21 Λ-S states of AsN molecule are studied for the first time for internuclear separations from 0.1 to 1.0 nm. Of these 21 Λ-S states, the X 1 Σ + , a′ 3 Σ + , 1 5 Σ + , 1 3 Δ, 1 3 Σ − , a 3 Π, 1 5 Π, 2 5 Σ + , 3 5 Σ + , 2 3 Δ, 2 3 Π, 3 3 Π, 3 5 Π, and A 1 Π states are found to be bound, and the 2 3 Σ + , 3 3 Σ + , 1 5 Σ − , 1 5 Δ, 2 5 Δ, 2 5 Π, and 1 7 Σ + states are found to be repulsive ones. The 3 3 Π state possesses the double well. The 2 5 Σ + , 3 5 Σ + , 3 5 Π, and 3 3 Π states possess the shallow well. The a′ 3 Σ + , 1 3 Σ − , 2 3 Π, 1 3 Δ, 1 5 Π, 2 5 Π, 3 5 Π, and 1 7 Σ + states are found to be the inverted ones with the spin–orbit coupling effect taken into account. The PECs are calculated using the CASSCF method, which is followed by the internally contracted MRCI approach with Davidson correction. Core–valence correlation and scalar relativistic corrections are included. The vibrational properties are evaluated for the 2 5 Σ + , 3 5 Σ + , and 3 5 Π states and the second well of the 3 3 Π state. The spin–orbit coupling effect is accounted for by the state interaction method with the Breit–Pauli Hamiltonian. The PECs are extrapolated to the complete basis set limit. The spectroscopic parameters are evaluated, and compared with available measurements and other theoretical results. The Franck–Condon factors and radiative lifetimes of the transitions from the a′ 3 Σ + 1 , a 3 Π 1 , A 1 Π 1 , 1 3 Δ 1 and a 3 Π 0− states to the X 1 Σ + 0+ state are calculated for several low vibrational levels, and some necessary discussion is performed. Analyses show that the spectroscopic parameters reported in this paper can be expected to be reliably predicted ones. - Highlights: • Effect of core–valence correlation and scalar relativistic corrections is included. • PECs are extrapolated to the CBS limit for the 21 Λ-S states and

  10. Decree no. 2004-48 from January 12, 2004 authorizing the French atomic energy commission to proceed to the definitive decommissioning and dismantling operations of the nuclear facility no. 43, named Saclay linear accelerator (ALS), on the territory of Saint-Aubin town (Essonne); Decret no. 2004-48 du 12 janvier 2004 autorisant le Commissariat a l'energie atomique a proceder aux operations de mise a l'arret definitif et de demantelement de l'installation nucleaire de base no. 43 denommee accelerateur lineaire de Saclay (ALS) sur le territoire de la Commune de Saint-Aubin (Essonne)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-01-01

    The linear accelerator of Saclay (ALS) has been the object of a commissioning permission given by decree by the French prime minister in October 8, 1965. It is submitted to the regime of basic nuclear facilities as defined in the decree no. 63-1228 from December 11, 1963. The French atomic energy commission (CEA) put down a request for the definitive decommissioning and dismantling of this facility on May 30, 2002. The duration foreseen for these operations is of 4 years. After the safety examination of the request by the DGSNR and the institute of radioprotection and nuclear safety (IRSN), a favorable and conformable advice has been given by the different ministries (health, finances and industry, ecology and sustainable development) and has led to this decree which precises the different protection measures to be implemented during the dismantling work. (J.S.)

  11. Decree no. 2002-447 of the 27 march 2002 authorizing the Normandy society of preserve and sterilization to realize definitive shutdowns and dismantling operations of the nuclear installation no. 152 situated on the territory of Osmanville (Calvados); Decret no. 2002-447 du 27 mars 2002 autorisant le Societe normande de conserve et sterilisation a proceder aux operations de mise a l'arret definitif et de demantelement de l'installation nucleaire de base no. 152 situee sur le territoire de la commune d'Osmanville (Calvados)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-01

    The decree presents the shutdown preliminary obligations, the installation quality, the prevention of radioactivity dissemination risk, the workers protection, the wastes management, the fire prevention. (A.L.B.)

  12. SFEN Annual Convention 2012 - The nuclear energy one year after Fukushima. Proceedings; Convention SFEN 2012 - Le nucleaire un an apres Fukushima. Recueil des presentations

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-03-15

    This document brings together the available presentations given at the 2012 edition of the Annual Convention of the French society of nuclear energy (SFEN) on the topic of nuclear energy one year after Fukushima. Twenty four presentations (slides) are compiled in this document: 1 - Presentation and introduction of the Annual Convention (Luc Oursel - SFEN President); 2 - Status of onsite/offsite remedial actions, key lessons learned (Akira Omoto, Tokyo univ., Japan Atomic Energy Commission); 3 - Complementary Safety Assessments (CSA) of the French NPP fleet (Dominique Miniere, EDF); 4 - Speech of M. Francois Fillon - Prime Minister; 5 - CSA of the fuel cycle facilities (Philippe Knoche, Areva); 6 - CSA of the EPR (Bertrand de l'Epinois, Areva; Jean-Luc Foret, EDF CNEN); 7 - The collective responsibility of the operators: the action of WANO (Laurent Stricker, WANO); 8 - Conclusions of French Nuclear Safety Authority (ASN) - Safety measures to be strengthened; 9 - Opinion no. 2012-AV-013 from January 3, 2012 of the French Nuclear Safety Authority - ASN (Sophie Mourlon, ASN; Caroline Lavarenne, IRSN); 10 - Nuclear energy: an energy for the future (Bernard Bigot, CEA); 11 - The nuclear phaseout in Germany from the view of German industry (Eberhard von Rottenburg, BDI); 12 - Prospects in China (Wei Lu, CGNP Europe); 13 - Industry Current Status and its Prospects in the United States (J. Spina, CENG); 14 - Nuclear energy prospects in France: recommendations of the Commission 'Energy 2050' (Jacques Percebois, Creden); 15 - Electrical generation system efficiency and economy (Yves Giraud, EDF); 16 - Electrical generation systems and distribution networks (Herve Mignon, Rte); 17 - Prospects in the UK (Tim Stone, DECC/OND, Senior Adviser to the Secretary of State); 18 - Climatic changes and energy policy (Laura Cozzi, IEA); 19 - The young nuclear professionals network (Boris Supiot, SFEN Young Generation Group); 20 - Socio-economic impacts of the nuclear power

  13. Nuclear energy; Le nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    This digest document was written by members of the union of associations of ex-members and retired people of the Areva group (UARGA). It gives a comprehensive overview of the nuclear industry world, starting from radioactivity and its applications, and going on with the fuel cycle (front-end, back-end, fuel reprocessing, transports), the nuclear reactors (PWR, BWR, Candu, HTR, generation 4 systems), the effluents from nuclear facilities, the nuclear wastes (processing, disposal), and the management and safety of nuclear activities. (J.S.)

  14. Nuclear wastes; Dechets nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    Here is made a general survey of the situation relative to radioactive wastes. The different kinds of radioactive wastes and the different way to store them are detailed. A comparative evaluation of the situation in France and in the world is made. The case of transport of radioactive wastes is tackled. (N.C.)

  15. Some fundamental aspects of boiling in nuclear reactors; Quelques aspects fondamentaux de l'ebullition dans les reacteurs nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Mondin, H; Lavigne, P; Semeria, R [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1964-07-01

    oscillation, the conditions of burnout are compared with those obtained under steady conditions. The burn-out flux following uniform 'stopped' heating has been studied in a channel containing still water. The flux shows a maximum as a function of unsaturation. The influence of the geometry and the nature of the metal was investigated. 4 - Output Oscillations: Using a low pressure (8 atm) loop, the influence of various parameters on the periods of output oscillations in a boiling channel on the thresholds at which they appear, was studied. Some new aspects of this complex phenomena were observed and are reported. (authors) [French] On indique les principaux resultats obtenus a Grenoble depuis quatre ans dans le domaine des mecanismes de l'ebullition et des phenomenes connexes dans les reacteurs nucleaires. 1 - OBSERVATION DE L'EBULLITION: Par photographie et cinematographie ultrarapide (8000 images par seconde maximum) on a observe l'ebullition en vase ou en canal jusqu'a 140 kg/cm{sup 2}. On a denombre les populations de germes (sites) generateurs de bulles et obtenu une correlation donnant leur nombre par unite de surface en fonction du flux thermique et de la pression. Le diametre des bulles se detachant de la paroi a ete etudie jusqu'a 140 kg/cm{sup 2}. On a mis en evidence trois types de bulles: - Les bulles en equilibre dont le diametre suit la formule de Fritz et Ende, - Les bulles d'ebullition dont le diametre diminue rapidement avec la pression (1/100 mm a 140 kg/cm{sup 2}), - Les coalescences apparaissant en liquide sature au-dessus de 15 W/cm{sup 2} et dont la proportion est independante de la pression. Par visualisation en strioscopie on observe les mouvements du film thermique associes a l'amorcage des germes, au depart et a la condensation des bulles; les mecanismes responsables de l'excellent transfert de chaleur ont pu ainsi etre precises. 2 - PERTES DE PRESSION EN ECOULEMENT DIPHASE: On a etabli un modele de variation continue du taux de vide dans un canal

  16. Differential measurement of the earth's magnetic field by nuclear magnetic resonance; Mesure differentielle du champ magnetique terrestre par resonance magnetique nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Robach, F [Commissariat a l' Energie Atomique, 38 - Grenoble (France). Centre d' Etudes Nucleaires

    1967-07-01

    MNR transducers using proton dynamic polarisation allows to convert into a phase measurement any variation of the earth magnetic field. There exist several versions of the instrument corresponding to various models of MNR transducers, which the author analyses in detail, devoting an important place to influence of their alignment with respect to the earth's magnetic field. The sensibility obtained is of one hundredth of a gamma over a bandwidth of (0-0,1 Hz). - This instrument is designed for measuring field gradients in airborne magnetic surveying, for detecting nearly magnetic anomalies, and for distinguishing between nearly and distant magnetic phenomena. (author) [French] L'emploi de capteurs, bases sur la resonance magnetique nucleaire des protons en presence de polarisation dynamique, permet de traduire une difference de champ magnetique terrestre en une mesure de phase. L'appareil existe sous plusieurs versions avec des capteurs de modeles differents dont l'auteur fait une analyse detaillee en accordant une part importante a l'influence de l'orientation des capteurs par rapport au champ magnetique terrestre. La sensibilite est de 1/100 {gamma} pour une bande passante de (0 - 0,1 Hz). Cet appareil s'applique a la mesure du gradient en prospection magnetique aeroportee, a la detection d'anomalies magnetiques proches, a la differentiation d'effets magnetiques proches et lointains. (auteur)

  17. Staff Organization in Nuclear Power Stations; Organisation du personnel des centrales nucleaires; Organizatsiya personala na atomnykh ehlektrostantsiyakh; Organizacion del personal de las centrales nucleares

    Energy Technology Data Exchange (ETDEWEB)

    Scuricini, G. B. [Comitato Nazionale Energia Nucleare, Roma (Italy)

    1963-10-15

    This paper deals with the organization of operating and maintenance staff at nuclear power stations in Italy and manpower variations, either because the plants themselves differ or are organized in some special way. Staff doing jobs for which a specific training is required are given special consideration in the paper. (author) [French] Dans le memoire, on examine l'organisation du personnel d'exploitation et d'entretien des centrales nucleaires italiennes et les differences existant dans les effectifs, differences dues soit aux caracteristiques des centrales memes, soit aux particularites d'organisation des entreprises. Le personnel charge de fonctions determinees pour lesquelles un entrainement special est requis, fait l'objet d'une attention particuliere. (author) [Spanish] En la memoria se examina la organizacion del personal de explotacion y conservacion de las centrales nucleares italianas y las diferencias que existen entre sus efectivos, diferencias que se deben a las caracteristicas de las mismas centrales o a las particularidades de organizacion de las empresas. El autor dedica especial atencion al personal encargado de funciones que requieren una formacion profesional especial. (author) [Russian] Issleduyutsya voprosy organizatsii personala, zanimayushchegosya ehkspluatatsiej ital'yanskikh atomnykh ehlektrostantsij i ukhodom za nimi, a takkhe razlichiya v sostave personala, vytekayushchie libo iz kharakternykh osobennostej samikh stantsij, libo iz osobennostej organizatsii predpriyatij. Osoboe vnimanie udelyaetsya personalu, kotoromu porucheny opredelennye funktsii, trebuyushchie spetsial'noj pod go tovki. (author)

  18. Damage caused to houses and equipment by underground nuclear explosions; Degats dus aux explosions nucleaires souterraines sur les habitations et les equipements

    Energy Technology Data Exchange (ETDEWEB)

    Delort, F; Guerrini, C [Commissariat a l' Energie Atomique, Bruyeres-le-Chatel (France). Centre d' Etudes

    1969-07-01

    A description is given of the damaged caused to various structures, buildings, houses, mechanical equipment and electrical equipment by underground nuclear explosions in granite. For each type of equipment or building are given the limiting distances for a given degree of damage. These distances have been related to a parameter characterizing the movement of the medium; it is thus possible to generalize the results obtained in granite, for different media. The problem of estimating the damage caused at a greater distance from the explosion is considered. (authors) [French] Les degats sur diverses structures, constructions, habitations, equipements mecaniques et materiels electriques provoques par des explosions nucleaires souterraines dans le granite sont decrits. On a indique pour chaque type de materiel ou de construction, les distances limites correspondant a un degre de gravite de dommage observe. Ces distances ont ete reliees a un parametre caracterisant le mouvement du milieu, permettant ainsi de generaliser les resultats obtenus dans le granite, a differents milieux. Le probleme de la prevision des degats en zone lointaine a ete aborde. (auteurs)

  19. Contribution to the Study of Nuclear Magnetic Resonance in Ferromagnets; Contribution a l'etude de la resonance nucleaire dans les corps ferromagnetiques

    Energy Technology Data Exchange (ETDEWEB)

    Robert, C. [Commissariat a l' Energie Atomique, Centre d' Etudes Nucleaires de Saclay, 91 - Gif-sur-Yvette (France)

    1962-07-01

    Properties of nuclear magnetic resonance in the field acting on the nucleus in a ferromagnet were studied. Nuclei were {sup 57}Fe in iron and yttrium iron garnet. Static properties of resonance (frequency, line-width, dipolar structure) were investigated and compared with magnetic behavior and magnetic structure of the materials. Relaxation in garnet points out importance of long range fluctuations induced by impurities in a ferromagnetic lattice. (author) [French] Nous avons etudie les proprietes de la resonance nucleaire dans le champ existant a remplacement d'un noyau dans un corps ferromagnetique (champ local). Les noyaux etaient ceux de {sup 57}Fe dans le fer et dans le grenat d'yttrium et de fer. Les proprietes statiques de la resonance (frequence de resonance, largeur de la raie, structures dues a l'interaction dipolaire) ont ete etudiees et reliees aux caracteristiques magnetiques et a la structure de ces corps. La relaxation dans le grenat a mis en evidence les fluctuations a longue distance induites par des impuretes dans un reseau ferromagnetique. (auteur)

  20. Contribution to the Study of Nuclear Magnetic Resonance in Ferromagnets; Contribution a l'etude de la resonance nucleaire dans les corps ferromagnetiques

    Energy Technology Data Exchange (ETDEWEB)

    Robert, C [Commissariat a l' Energie Atomique, Centre d' Etudes Nucleaires de Saclay, 91 - Gif-sur-Yvette (France)

    1962-07-01

    Properties of nuclear magnetic resonance in the field acting on the nucleus in a ferromagnet were studied. Nuclei were {sup 57}Fe in iron and yttrium iron garnet. Static properties of resonance (frequency, line-width, dipolar structure) were investigated and compared with magnetic behavior and magnetic structure of the materials. Relaxation in garnet points out importance of long range fluctuations induced by impurities in a ferromagnetic lattice. (author) [French] Nous avons etudie les proprietes de la resonance nucleaire dans le champ existant a remplacement d'un noyau dans un corps ferromagnetique (champ local). Les noyaux etaient ceux de {sup 57}Fe dans le fer et dans le grenat d'yttrium et de fer. Les proprietes statiques de la resonance (frequence de resonance, largeur de la raie, structures dues a l'interaction dipolaire) ont ete etudiees et reliees aux caracteristiques magnetiques et a la structure de ces corps. La relaxation dans le grenat a mis en evidence les fluctuations a longue distance induites par des impuretes dans un reseau ferromagnetique. (auteur)

  1. Thermal energy of nuclear origin produced in non-fissile materials (1962); Energie calorifique d'origine nucleaire degagee dans les materiaux non fissiles (1962)

    Energy Technology Data Exchange (ETDEWEB)

    Naudet, G [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires; Millies, P; Berger, J [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1962-07-01

    A first part is devoted to the description of the interaction phenomena between elementary particles and material that may be observed during the irradiation process in a nuclear reactor: nuclear reactions due to neutrons, production of gamma rays and absorption of those gamma rays through various processes. In a second part the phenomena producing calorific energy in irradiated material are quantitatively examined. In the third part results are summed up in a formulary. The fourth part presents tables and figures giving to the reader all the numerical values necessary for practical calculations. (authors) [French] Une premiere partie est consacree a l'examen des principaux phenomenes d'interaction des particules avec la matiere qui interviennent lors d'une irradiation dans un reacteur: reactions nucleaires dues aux neutrons, production des rayons gamma et absorption de ces derniers par les divers processus. Une deuxieme partie etudie quantitativement les phenomenes qui conduisent a l'apparition d'energie calorifique dans le materiau irradie. En troisieme partie, un formulaire resume les resultats etablis. Dans une quatrieme partie, des tableaux et des courbes fournissent a l'experimentateur toutes les valeurs numeriques necessaires aux calculs pratiques. (auteurs)

  2. Factors and uncertainties in the profitability of using nuclear energy in desalination of water; Facteurs et incertitudes de la rentabilite du recours a l'energie nucleaire dans le dessalement des eaux

    Energy Technology Data Exchange (ETDEWEB)

    Thiriet, L; Lievre, P [Commissariat a l' Energie Atomique, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

    1969-07-01

    One of the economic advantages of nuclear energy consists of the small proportional element in its cost structure. Economies of scale favour the nuclear station as compared with the conventional thermal one, and when the demand for electricity and heat, in particular for desalination, are sufficient, nuclear energy may, subject to certain conditions, prove advantageous. The object of this paper is to discuss the validity of the conclusions reached according to the hypotheses adopted. In the first part, the different kind of uncertainties connected with technical, economic and financial data (the various transmission coefficients, the life of equipment according to the choice of materials, changes in prices, the form of price functions and interest rates), and with the various constraints, are examined and discussed. In the second part the uncertainties connected with the method of optimisation used and the criterion of selection adopted are examined and discussed. It is shown thereby that it is usually extremely difficult to assume absolutely the competitiveness, or conversely the non-competitiveness, of using nuclear energy in the desalination of water, and that a large number of aspects have to be carefully examined. (author) [French] On sait que l'un des avantages economiques de l'energie nucleaire reside dans la faible part proportionnelle dans la structure de son cout. Les economies d'echelle favorisent le nucleaire par rapport au thermique classique, et lorsque les demandes d'electricite et de chaleur, notamment pour le dessalement, sont suffisantes on peut envisager favorablement, sous certaines hypotheses, le recours a l'energie nucleaire. L'objet de cette communication est de discuter la validite des conclusions auxquelles on parvient selon les hypotheses envisagees. Dans une premiere partie, on etudie et on discute les differentes sortes d'incertitudes, liees aux donnees techniques, economiques et financieres (les divers coefficients de transmission, les

  3. Nuclear magnetic resonance of iron-57 nuclei in local fields in yttrium and iron garnets; Resonance magnetique nucleaire des noyaux du fer 57 dans les champs locaux du grenat d'yttrium et de fer

    Energy Technology Data Exchange (ETDEWEB)

    Robert, C. [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1961-07-01

    We have demonstrated the nuclear resonance of {sup 57}Fe nuclei in the local field of each of the two magnetic sub-lattices of yttrium and iron garnets. The resonance frequencies and the relaxation times have been measured as a function of the temperature. (author) [French] Nous avons mis en evidence la resonance nucleaire des noyaux de {sup 57}Fe dans le champ local de chacun des deux sous-reseaux magnetiques du grenat d'yttrium et de fer. Les frequences de resonances et les temps de relaxation ont ete mesures en fonction de la temperature. (auteur)

  4. Is it possible to recycle nuclear wastes? Costs, risks and stakes of the plutonium industry; Peut-on recycler les dechets nucleaires? Couts, risques et enjeux de l'industrie du plutonium

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    This document, published by the French association 'Sortir du nucleaire' (Get out of nuclear), gives some information on the chain reaction from uranium to plutonium, the difference between reprocessing (which does not reduce waste volumes but multiply waste types) and recycling, the high risks associated with plutonium transport, La Hague as the most dangerous nuclear site in France, reprocessing as the alibi for the French nuclear industry, Areva as an expert in propaganda, reprocessing as an absurd world strategy, plutonium as a fuel for proliferation, the myth of unlimited energy with the breeder reactors, and so on

  5. Guatemala: Ozbrojený konflikt 1960-1996 a současná situace: se zvláštním zaměřením na Máje

    OpenAIRE

    Vilímková, Olga

    2009-01-01

    Tématem disertační práce je Guatemala: ozbrojený konflikt v letech 1960 - 1996 a současná situace se zvláštním zaměřením na Máje. Příčiny ozbrojeného konfliktu druhé ploviny XX. století (a mnoha současných problémů) v Guatemale se nacházejí v hluboké minulosti země. Už v době koloniální se začaly formovat ekonomicko - sociální vztahy mezi dvěma antagonistickými vrstvami společnosti: kolonizátory a původním obyvatelstvem, které bylo porobeno, vytlačeno na okraj společnosti a využíváno jako pra...

  6. Information note about the protection of nuclear facilities against aircraft crashes; Note d'information sur la protection des installations nucleaires contre les chutes d'avions

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    The protection of nuclear facilities against external risks (earthquakes, floods, fires etc..) is an aspect of safety taken into consideration by the French authority of nuclear safety (ASN). Concerning the aircraft crashes, the fundamental safety rules make three categories of aircraft: the small civil aircraft (weight < 5.7 t), the military aircraft, and the commercial aircraft (w > 5.7 t). Nuclear facilities are designed to resist against crashes of aircraft from the first category only, because the probability of the accidental crash of a big aircraft are extremely low. This document comprises an information note about the protection of nuclear facilities against aircraft crashes, a dossier about the safety of nuclear facilities with respect to external risks in general (natural disasters and aircraft crashes), and an article about the protection of nuclear power plants against aircraft crashes (design, safety measures, regulation, surveillance, experience feedback). (J.S.)

  7. Reports by the Parliamentary Office for scientific and technological assessments. Thursday, April 14, 2011. Information on the Fukushima accident by Mr Thomas Houdre, Nuclear plant manager by the Nuclear Safety Authority. Nuclear safety, the role and future of the sector - Presentation of the feasibility study; Comptes rendus de l' Office Parlementaire d'Evaluation des Choix Scientifiques et Technologiques. Jeudi 14 avril 2011. Point d'information sur l'accident de Fukushima par M. Thomas Houdre, directeur des centrales nucleaires de l'Autorite de Surete Nucleaire. Securite nucleaire, place de la filiere et son avenir - Presentation de l'etude de faisabilite

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-04-15

    In a first part, a representative of the ASN describes the situation of the Fukushima Daiichi nuclear power station about one month after the accident. He reports the phenomena which have occurred, gives some explanations, compares this accident with that of Chernobyl. The second part is a discussion about the content and the organization of a parliamentary mission which aims at investigating nuclear safety, and the role and future of the nuclear sector

  8. Professional Nuclear Materials Management; Gestion Industrielle des Matieres Nucleaires; Obrashchenie s yadernymi materialami na professional'nom urovne; Administracion Eficiente de Materiales Nucleares

    Energy Technology Data Exchange (ETDEWEB)

    Forcella, A. A.; O' Leary, W. J. [Allis-Chalmers Manufacturing Company, Bethesda, MD (United States)

    1966-02-15

    . (author) [French] Le memoire expose en quoi consiste la gestion des matieres nucleaires dans une centrale nucleaire type, aux Etats-Unis. Comme le reacteur en question est partiellement finance a l'aide de capitaux prives, l'une des principales obligations de l'exploitant est d'assurer la protection et la rentabilite des investissements. Etant donne que les matieres nucleaires sont d'une valeur intrinseque elevee, il faut constamment proceder a des controles appropries allant au-dela des mesures de securite et de la comptabilite interessant les matieresnucleaires proprement dites afin de reduire les pertes au minimum. Il faut faire preuve de clairvoyance et planifier judicieusement pour prevenir toute perte supplementaire de capital provenant de frais inutiles ou d'un manque a gagner dans divers secteurs de l'exploitation. C'est ainsi que le gestionnaire de matieres nucleaires doit prendre des dispositions pour garantir la bonne marche des operations et assurer le respect des plans d'execution par une liaison et un controle constants, dans les domaines suivants? a) acquisition du combustible et des elements combustibles, b) utilisation des elements combustibles dans le reacteur et c) recuperation, dans le combustible irradie, des produits et matieres presentant de l'interet. Pendant la periode qui precede l'utilisation du reacteur, il faut faire une place importante dans la planification et les travaux preparatoires aux considerations d'economie dans la conception des elements combustibles, en ce qui concerne leur fabrication, leur manutention, leur transport et leur remplacement. Les differentes etapes de la fabrication doivent etre planifiees de facon a reduire au minimum le manque a gagner du a des periodes improductives d'entreposage de matieres tres couteuses. Pendant la marche du reacteur, il faut assurer une combustion maximale de la matiere fissile par des redistributions appropriees du combustible dans le coeur du reacteur. Parallelement, les temps morts dus a

  9. The pulsed neutron method applied to the determination of the nuclear constants of graphite (1961); La methode des neutrons pulses appliquee a la determination des constantes nucleaires du graphite (1961)

    Energy Technology Data Exchange (ETDEWEB)

    Lalande, J [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1961-07-01

    A method for determining the nuclear constants {sigma}{sub a} and {lambda}{sub t} of a moderator is described. The disappearance of a burst of neutrons introduced into a finite medium is studied as a function of time. This decrease in the thermal neutron density is the product of two exponentials; one representing the absorption, the other the leakage. By varying one or other of these factors, the constants of the factor left unvaried can be determined, and from this the nuclear constant values are deduced. (author) [French] On decrit une methode permettant de determiner les constantes nucleaires {sigma}{sub a} et {lambda}{sub t} d'un moderateur. On etudie la decroissance dans le temps d'une bouffee de neutrons introduite dans un milieu fini. Cette decroissance de la densite en neutrons thermiques est le produit de deux exponentielles; l'une represente l'absorption, l'autre les fuites. Par variation de l'un ou l'autre de ces facteurs, on determine les constantes du facteur laisse invariant dont on deduit les valeurs des constantes nucleaires. (auteur)

  10. General problems arising from the analogical resolution of the kinetic equations of nuclear reactors (1961); Problemes generaux poses par la resolution analogique des equations cinetiques des reacteurs nucleaires (1961)

    Energy Technology Data Exchange (ETDEWEB)

    Caillet, C [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1961-07-01

    The author reviews precisely the analogical techniques used for the resolution of the kinetic equations of nuclear reactors. Prior to this, he recalls the reasons which oblige physicians and engineers, even today, to use electronic machines in this domain. The author then considers the technological problems posed by the range of values which the various nuclear parameters adopt. In each case, he shows that a compromise is possible allowing an optimum precision. He compares the results to those obtained by arithmetic calculation and uses the examples chosen in a critical analysis of the present possibilities of the two methods of calculation. (author) [French] L'auteur cherche a faire un point aussi exact que possible des techniques analogiques utilisees pour resoudre les equations cinetiques des reacteurs nucleaires. Il rappelle auparavant les raisons pour lesquelles physiciens et ingenieurs sont obliges, encore aujourd'hui, de faire appel aux machines electroniques dans ce domaine. Puis il etudie les problemes technologiques que souleve le champ des valeurs prises par les differents parametres nucleaires. Dans chacun des cas, il montre l'existence d'un compromis qui permet d'atteindre une precision optimum. Il compare les resultats obtenus a ceux provenant de calculateurs arithmetiques et profite des exemples choisis pour faire une analyse critique des possibilites actuelles offertes par les deux modes de calcul. (auteur)

  11. Report realized on behalf of the Foreign Affairs Commission, of Defense and Armed Forces on the law project allowing the agreement approbation between the French Republic Government and the Russian Federal Government relative to the civil liability concerning the nuclear damages occurring from goods supplying to nuclear facilities in Russian Federation and becoming from the French Republic; Rapport fait au nom de la commission des affaires etrangeres, de la defense et des forces armees sur le projet de loi autorisant l'approbation de l'accord entre le Gouvernement de la Republique francaise et le Gouvernement de la Federation de Russie relatif a la responsabilite civile au titre de dommages nucleaires du fait de fournitures en provenance de la Republique francaise destinees a des installations nucleaires en Federation de Russie

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-01

    The first part presents the international civil liability system in the nuclear domain and details then the 20 june 2000 agreement. It presents also the main aspects of the french-russian cooperation in the nuclear domain. (A.L.B.)

  12. General trends in the use of uranium in the nuclear industry; Tendances generales d'emploi de l'uranium dans les industries nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Salesse, M [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1960-07-01

    It can be seen from a consideration of the development of the military and civil needs for uranium that, in the long run, the main outlet for the metal will be provided by its industrial applications. The technical uncertainties concerning the best method of producing atomic energy are still numerous and in fact reflect the hesitation in choosing one of two classes of fuel: that based on the metal and that based on the oxide. Four main factors should influence the choice: - the neutron reactivity and the enrichment of the uranium; - the operating temperature; - the resistance to radiation effects; - the chemical stability; but in actual fact, when the choice for a particular use has to be made, it will be another type of factor, such as the cost price, and weight and space considerations which will determine the choice of either metallic uranium or uranium oxide reactors. (author) [French] D'apres le developpement des besoins militaires ou civils en uranium, on voit que les usages industriels de ce metal constituent, a long terme, le debouche essentiel. Les incertitudes techniques, sur le procede optimum pour faire de l'energie nucleaire, restent nombreuses, et se traduisent finalement par une hesitation entre deux grandes classes de combustibles: ceux a base de metal et ceux a base d'oxyde: la preference a l'une ou l'autre de ces deux categories doit s'inspirer de quatre considerations: - la reactivite neutronique et l'enrichissement de l'uranium; - la temperature de fonctionnement; - la resistance aux effets du rayonnement; - la stabilite chimique; mais en definitive, lorsqu'il s'agira d'une application determinee, ce seront des considerations d'un autre ordre, comme le prix de revient, le poids et l'encombrement, qui determineront le choix entre piles a uranium metallique et piles a oxyde d'uranium. (auteur)

  13. The design and construction of a nuclear free-precession magnetometer; Etude et realisation d'un magnetometre a precession libre nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Baconnier, Y [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1960-10-15

    After presenting the advantages of nuclear magnetic resonance with respect to electromagnetic processes, as far as the measurement of the earths' magnetic field is concerned, we deal with the macroscopic theory for the Bloch model and analyse Packard and Varions' experiment. The development of a particular absolute free-precession magnetometer is studied, and the conditions are determined for obtaining a maximum amplitude signal as a function of the geometrical form of the detector coil, of the method of cut-off, and of the coupling between various parts of the system. After having described in detail the technology of amplifiers, we consider the problem of the measurement of the frequency of precession for which an original solution, of analogy form, is proposed and discussed. Complete plans of the equipment are given in an appendix. (author) [French] Apres avoir presente les avantages de la resonance magnetique nucleaire relativement aux procedes electromagnetiques, en ce qui concerne la mesure du champ magnetique terrestre, on traite de la theorie macroscopique dans le modele de Bloch et analyse l'experience de Packard et Varian. On etudie une realisation particuliere d'un magnetometre absolu a precession libre et determine les conditions d'obtention d'un signal d'amplitude maximale en fonction de la forme geometrique du bobinage detecteur, de la methode de coupure, et du couplage entre les differents elements du montage. Apres avoir decrit en detail la technologie des amplificateurs, on aborde le probleme de la mesure de la frequence de precession, pour laquelle une solution originale, sous forme analogique, est proposee et discutee. En annexe est joint un dossier complet des plans de la realisation. (auteur)

  14. Contribution to the study of nuclear fuel materials with a metallic uranium base; Contribution a l'etude des materiaux combustibles nucleaires a base d'uranium metallique

    Energy Technology Data Exchange (ETDEWEB)

    Englander, M [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1957-11-15

    In a power reactor destined to supply industrially recoverable thermal energy, the most economical source of heat still consists of natural metallic uranium. However, the nuclear fuel material, most often employed in the form of rods of 20 to 40 mm diameter, is subjected to a series of stresses which lead to irreversible distortions usually incompatible with the substructure of the reactor. As a result the fuel material must possess at the outset a certain number of qualities which must be determined. Investigations have therefore been carried out, first on the technological characters peculiar to each of the three allotropic phases of pure uranium metal, and on their interactions on the stabilisation of the material which consists of either cast uranium or uranium pile-treated in the {gamma} phase. (author) [French] Dans un reacteur de puissance destine a fournir de l'energie thermique industriellement recuperable, la source de chaleur la plus economique reste constituee par de l'uranium metallique naturel. Or, le materiau combustible nucleaire, employe le plus souvent sous forme de barreaux de 20 a 40 mm de diametre, se trouve soumis a un ensemble de contraintes qui provoque des deformations irreversibles, le plus souvent incompatibles avec l'infrastructure du reacteur. Par consequent, le materiau combustible doit presenter a l'origine un certain nombre de qualites qu'il est necessaire de determiner. Aussi a-t-on d'abord etudie les caracteres technologiques propres a chacune des trois phases allotropiques de l'uranium-metal pur et leurs interactions sur la stabilisation du materiau constitue soit par de l'uranium coule, soit par de l'uranium traite en pile en phase {gamma}. (auteur)

  15. Contribution to the study of solid helium-3 by nuclear magnetic resonance; Contribution a l'etude de l'helium trois solide par resonance magnetique nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Landesman, A [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1968-07-01

    Due to the unusually large zero point motion of helium three atoms in the solid, the overlap of the atomic wave functions is very important. As a consequence, there are exchange interactions, the theoretical calculation and the experimental measurement of which are discussed. Nuclear magnetic resonance is especially well suited for the latter.A detailed theory is given for both exchange narrowing and Zeeman-exchange cross relaxation, which phenomena are used to measure the exchange interaction as a function of molar volume. The alignment temperature is thus known; it goes down when the pressure goes up and is never higher than three milli degrees. An influence of helium four impurities on the exchange interactions between helium three atoms which are neighbours of the substitutional He is shown. (author) [French] Par suite de l'amplitude exceptionnelle des mouvements de point zero dans l'helium trois solide, le recouvrement des fonctions d'onde atomiques est tres important. Il en resulte des interactions d' echange dont on discute l'evaluation theorique et la mise en evidence experimentale. Cette derniere peut se faire par resonance magnetique; on etudie theoriquement les phenomenes de retrecissement par echange et de relaxation Zeeman-echange que l'on met a profit pour determiner les interactions d'echange en fonction du volume molaire. On en deduit que la temperature d'alignement nucleaire diminue quand on comprime le solide et est au plus de 3x10{sup -3} K. L'influence des impuretes d'helium quatre sur les interactions d'echange entre atomes {sup 3}He voisins de {sup 4}He est mise en evidence. (auteur)

  16. New features of nuclear excitation by {alpha} particles scattering; Nouveaux aspects de l'excitation nucleaire par diffusion de particules {alpha}

    Energy Technology Data Exchange (ETDEWEB)

    Saudinos, J [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1962-07-01

    Inelastic scattering of medium energy a particles by nuclei is known to excite preferentially levels of collective character. We have studied the scattering of isotopically enriched targets of Ca, Fe, Ni, Cu, Zn. In part I, we discuss the theoretical features of the interaction. In part II, we describe the experimental procedure. Results are presented and analysed in part III. {alpha} particles scattering by Ca{sup 40} is showed to excite preferentially odd parity levels. In odd nuclei we have observed multiplets due to the coupling of the odd nucleon with the even-even core vibrations. For even-even nuclei, a few levels are excited with lower cross-sections between the well-known first 2{sup +} and 3{sup -} states. Some could be members of the two phonon quadrupole excitation and involve a double nuclear excitation process. (author) [French] On sait que la diffusion inelastique des particules alpha de moyenne energie excite preferentiellement des niveaux de caractere collectif. Nous avons etudie la diffusion des particules alpha de 44 MeV du cyclotron de Saclay par des isotopes separes de Ca, Fe, Ni, Cu, Zn. Dans la premiere partie nous exposons les theories de cette interaction. Dans la seconde nous decrivons le systeme experimental. Les resultats sont donnes dans la troisieme partie. Nous montrons que les niveaux excites preferentiellement pour {sup 40}Ca par diffusion ({alpha},{alpha}') sont de parite negative. Dans les noyaux pair-impair nous avons observe des multiplets dus au couplage du nucleon celibataire avec les vibrations du coeur pair-pair. Pour les noyaux pair-pair nous avons pu etudier entre le premier niveau 2{sup +} et le niveau 3{sup -} deja bien connus certains etats plus faiblement excites. Il semble qu'ils sont dus a une excitation quadrupolaire a deux phonons et impliquent un processus de double excitation nucleaire. (auteur)

  17. Issuing of Regulations on the Clearance of Irradiated Food Products on the Basis of Foreign Petitions; Promulgation d'un Reglement Regissant l'Autorisation de Commercialiser des Denrees Alimentaires Irradiees, sur la Base de Demandes Fondees sur des Donnees Elaborees a l'Etranger; Protsedura polucheniya razreshenij na prodazhu obluchennykh pishchevykh produktov na baze inostrannykh khodatajstv; Autorizacion del Consumo de Productos Alimenticios Irradiados, Sobre la Base de Investigaciones Realizadas en el Extranjero

    Energy Technology Data Exchange (ETDEWEB)

    Foa, E.; Eisenberg, E.; Kahan, R. S.; Lapidot, M. [Soreq Nuclear Research Centre, Yavne (Israel)

    1966-11-15

    Since the beginning of 1965, Israel has been interested in legal problems on the clearance of irradiated food and in the installation of a food irradiator. Supervision and control of the irradiation, and distribution of the irradiated products, the applications of relevant laws, or their enactment where none exist, are some points of special importance among those dealt with. Most legislation now requires that the wholesomeness of irradiated food be proven unequivocably before irradiation and consumption of the food are authorized. Such proof, however, is beyond the means of small, and of developing countries, the very ones which could most benefit from the introduction of irradiation techniques on an industrial scale, since this would increase both the availability of local foods for internal consumption and also export possibilities. As a test case, on 24 February 1966, a petition was submitted to the Israel Ministry of Health for permission to use, for human consumption, white potatoes which had been irradiated to prevent sprouting. The petition was based not on local work, but on that published abroad, with the request that the wholesomeness tests approved by other governments be accepted as sufficient proof. Another similar petition on the use of irradiated onions will be submitted shortly. If successful, this procedure could be adopted by other countries and might facilitate international trade agreements. It could be instrumental in the rapid development of the application of irradiation for food preservation in places where it could prove of useful economic value. (author) [French] Depuis le debut de 1965, Israeel s'interesse aux problemes juridiques que'pose l'autorisation de vendre des aliments irradies et a l'installation d'un irradiateur. Parmi les points les plus importants qui font l'objet d'une etude, il convient de citer le controle de l'irradiation et de la distribution des produits irradies, l'application des lois pertinentes et, le cas echeant

  18. Health problems raised by the elimination of radioactive wastes and nuclear accidents; Problemes sanitaires poses par l'elimination des dechets radioactifs et par les accidents nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Jammet, H.; Mechali, D.; Dousset, M. [Commissariat a l' Energie Atomique, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

    1964-07-01

    The rapid development of nuclear energy demands an urgent solution to the health problems arising from the discharge into the environment of radioactive residues produced by nuclear installations. - To be able to evaluate the risks run by the population and to fix tolerance limits for waste discharge, it is necessary to possess an exact knowledge of the course taken by the radioelements discharged, from their source until they reach man. The incorporation of radioelements in food cycles is the first risk to take into consideration. The factors involved in all stages of this transmission must be foreseen, whether they concern physical or biological media, because of their continuity and their interdependence. Finally, socio-economic and dietetic data must be collected in order that the risks and tolerance levels estimated are based on concrete and experimental rather than theoretical knowledge. The risk of nuclear accidents in the atomic industry, although very improbable, must be taken into consideration because of the seriousness of their consequences. The health problems arise in the field of professional hygiene on the one hand and in that of public hygiene on the other. In the first field the risk is two-fold and involves irradiation and contamination. The public sphere is reduced essentially to the risk of contamination by radioactive substances accidentally released in the surrounding medium. The health studies to be conducted in this field therefore include research not only on irradiation or contamination therapeutics but also on the transfer of radioelements from the accident site to man, mainly through food cycles, in their physical and in their biological components. Studies of this kind form the basis of decisions in the health field which would have to be taken in the case of an accident. (authors) [French] Le developpement rapide de l'energie nucleaire rend urgente la solution des problemes sanitaires poses par le rejet dans le milieu ambiant des

  19. Motywacja i wpływ uprawiania jogi na stan zdrowia – badanie własne = Motivation and influence practicing yoga on health - own study

    Directory of Open Access Journals (Sweden)

    Katarzyna Gwis

    2016-09-01

      Motywacja i wpływ uprawiania jogi na stan zdrowia – badanie własne Motivation and influence practicing yoga on health - own study   Katarzyna Gwis1, Dominik Olejniczak2, Joanna Skonieczna2   1 Absolwentka kierunku Zdrowie Publiczne Wydział Nauki o Zdrowiu Warszawski Uniwersytet Medyczny   2 Warszawski Uniwersytet Medyczny Zakład Zdrowia Publicznego ul. Banacha 1a, 02-097 Warszawa   Słowa kluczowe: joga, zdrowie, zachowania zdrowotne Key words: yoga, health, health behavior   Streszczenie Wprowadzenie i cel pracy: Joga to jedna z form aktywności ruchowej. Joga oddziałuje na ciało i na umysł, dzięki czemu w prosty sposób pomaga zachować zdrowie. Celem badania była ocena wpływu uczestnictwa w zajęciach jogi na zdrowie. Materiał i metoda: Grupę badaną stanowiło 50 osób uczęszczających na zajęcia jogi. Udział w ankiecie był dobrowolny i poufny. Zastosowano autorski kwestionariusz. Wyniki: W grupie badanych, aż 48 osób (96% stwierdziło, że ćwiczenia jogi pozytywnie wpływają na kształtowanie nawyków ruchowych. Ponad połowa badanych - 26 osób (52% stwierdziła, że uczęszczanie na zajęcia jogi sprawiło, że wzrosło ich zainteresowanie zdrowym odżywianiem. Ponad połowa badanych – 26 osób (52% jako główną korzyść płynącą z ćwiczeń jogi wskazała wzrost sprawności fizycznej. Ponad połowa osób ankietowanych – 28 osób (56% zaobserwowała, że od kiedy ćwiczy jogę stany chorobowe występują rzadziej.  Wnioski: Analizując wyniki przeprowadzonego badania własnego oraz dyskusję można stwierdzić, iż w związku z udokumentowanym pozytywnym wpływem jogi na stan zdrowia warto jest propagować tą formę rekreacji ruchowej we wszystkich grupach wiekowych, poczynając od dzieci, a  kończąc na osobach w  podeszłym wieku.       Abstract   Introduction: Yoga is a form of physical activity. Yoga affects the body and the mind, making it an easy way to help maintain good health. The aim of this

  20. Determination of radioactive risks connected with the working of a nuclear plant; Evaluation des risques radioactifs lies au fonctionnement d'une installation nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Lavie, J M; Doury, A [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1960-07-01

    Numerous problems which are posed by the evaluation of the radioactive risks linked to the working of a nuclear plant are new problems which have not yet been satisfactorily solved. In these conditions this study must be considered only as a preliminary approach whose essential aims are the following: - development and synthesis of the existing data; - rapid determination of conservative and usable orders of greatness for the security factors, both for normal working and in the case of an accident. The most probable typical accidents are reviewed together with the nature of the resulting risks and the principal factors on which these risks depend. Among these factors, one of the most important is atmospheric diffusion which is studied in some detail using the analytic model due to Sutton. A logical graphical presentation increasing the flexibility in the use of the results and presents the responsible authorities with a flexible, practical and rapid means of evaluating the risks involved starting from a sufficiently general system of initial and simultaneously valid conditions (types of accident, atmospheric conditions). (author) [French] De nombreux problemes souleves par l'evaluation des risques radioactifs lies au fonctionnement d'une installation nucleaire sont des problemes nouveaux qui n'ont pas encore recu de solution satisfaisante. Dans ces conditions cette etude ne doit etre consideree que comme une premiere approche dont les objectifs essentiels sont les suivants: - mise au point et synthese de donnees existantes; - determination rapide d'ordres de grandeur conservatifs et utilisables de valeurs de securite, tant en fonctionnement normal qu'en cas d'accident. Les accidents types les plus probables sont passes en revue ainsi que la nature des risques qui en decoulent et les principaux facteurs dont dependent ces risques. Parmi ces facteurs, l'un des plus importants est la diffusion atmospherique qui fait l'objet d'une etude particuliere a l'aide du modele

  1. Can-rupture detection in gas-cooled nuclear reactors; La detection des ruptures de gaine dans les piles nucleaires refroidies par gaz

    Energy Technology Data Exchange (ETDEWEB)

    Roguin, A. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1965-07-01

    Can-rupture detection (DRG) is one important aspect of pile safety, more particularly so in the case of gas-cooled reactors. A rapid and sure detection constitutes also an improvement as far as the efficiency of electricity-producing nuclear power stations are concerned. Among the numerous can-rupture detection methods, that based on the measurement of the concentration of short-lived fission gases in the heat-carrying fluid has proved to be the most sensitive and the most rapid. A systematic study of detectors based on the electrostatic collection of the daughter products of fission gases has been undertaken with a view to equip the reactors EL 2, G 3, EDF 1, EDF 2 and EDF 3, the gas loops of PEGASE and EL 4. The different parameters are studied in detail in order to obtain a maximum sensitivity and to make it possible to construct detection devices having the maximum operational reliability and requiring the minimum maintenance. The primary applications of these devices are examined in the case of the above-mentioned reactors. (author) [French] La Detection des Ruptures de Gaines (D. R. G.) est un aspect important de la securite des piles et plus particulierement des piles refroidies par un gaz. Une detection rapide et sure constitue aussi un element d'amelioration du rendement des centrales nucleaires productrices d'energie electrique. Parmi les nombreuses methodes de detection des ruptures de gaines, la mesure de la concentration dans le fluide caloporteur des gaz de fission a vie courte s'est revelee comme la plus sensible et la plus rapide. Une etude systematique des detecteurs a collection electrostatique des descendants des gaz de fission a ete entreprise en vue d'equiper les piles EL 2, G 3, EDF 1, EDF 2 et EDF 3, les boucles a gaz de la pile Pegase et la pile EL 4. Les divers parametres sont etudies en detail pour obtenir une sensibilite maximum et permettre la realisation de dispositifs de detection ayant le maximum de securite de

  2. Can-rupture detection in gas-cooled nuclear reactors; La detection des ruptures de gaine dans les piles nucleaires refroidies par gaz

    Energy Technology Data Exchange (ETDEWEB)

    Roguin, A [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1965-07-01

    Can-rupture detection (DRG) is one important aspect of pile safety, more particularly so in the case of gas-cooled reactors. A rapid and sure detection constitutes also an improvement as far as the efficiency of electricity-producing nuclear power stations are concerned. Among the numerous can-rupture detection methods, that based on the measurement of the concentration of short-lived fission gases in the heat-carrying fluid has proved to be the most sensitive and the most rapid. A systematic study of detectors based on the electrostatic collection of the daughter products of fission gases has been undertaken with a view to equip the reactors EL 2, G 3, EDF 1, EDF 2 and EDF 3, the gas loops of PEGASE and EL 4. The different parameters are studied in detail in order to obtain a maximum sensitivity and to make it possible to construct detection devices having the maximum operational reliability and requiring the minimum maintenance. The primary applications of these devices are examined in the case of the above-mentioned reactors. (author) [French] La Detection des Ruptures de Gaines (D. R. G.) est un aspect important de la securite des piles et plus particulierement des piles refroidies par un gaz. Une detection rapide et sure constitue aussi un element d'amelioration du rendement des centrales nucleaires productrices d'energie electrique. Parmi les nombreuses methodes de detection des ruptures de gaines, la mesure de la concentration dans le fluide caloporteur des gaz de fission a vie courte s'est revelee comme la plus sensible et la plus rapide. Une etude systematique des detecteurs a collection electrostatique des descendants des gaz de fission a ete entreprise en vue d'equiper les piles EL 2, G 3, EDF 1, EDF 2 et EDF 3, les boucles a gaz de la pile Pegase et la pile EL 4. Les divers parametres sont etudies en detail pour obtenir une sensibilite maximum et permettre la realisation de dispositifs de detection ayant le maximum de securite de fonctionnement et le

  3. SCPRI Emergency Kit for Use in the Event of a Nuclear Accident; Le Dispositif d'Intervention Rapide du SCPRI en Cas d'Accident Nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Ervet, P.; Moroni, J. P.; Pellerin, P. [Service Central de Protection Contre les Rayonnements Ionisants, Ministere des Affaires Sociales, Le Vesinet (France)

    1969-10-15

    In the event of a nuclear accident necessitating implementation of the ORSEC radiation protection plan, the Service central de protection contre les rayonnements ionisants (Central Service for Protection against Ionizing Radiations), in conjunction with the Service national de la protection civile (National Civil Defence Service), has adopted the necessary measures for rapid evaluation of possible contamination as promptly as possible. With this aim in mind the Service has prepared emergency kits, which are permanently stored at airfields in the Paris region; these can be carried by aircraft together with two engineers from the Service, thereby enabling them to reach the site of the incident with the specialized equipment in a few hours at most. This paper describes the monitoring and sampling equipment as well as the conditions under which the kit is carried and used (it operates independently by having a built-in generating unit). It is basically designed to permit an initial assessment of the situation, to furnish local authorities with data on which to base decisions for the safety of the population, and to determine any additional measures that need to be adopted. (author) [French] Dans le cas d'un accident nucleaire impliquant la mise en application du plan ORSEC radiologique, en liaison avec le Service national de la protection civile, le Service central de protection contre les rayonnements ionisants a pris les dispositions necessaires pour faire une evaluation rapide, aussi preooce que possible, des contaminations eventuelles. Dans ce but, il a realise des cantines d'intervention qui sont deposees en permanence sur les aerodromes de la region parisienne, et peuvent etre embarquees par avion avec deux ingenieurs du service qui peuvent etre ainsi sur les lieux de l'incident, avec un materiel specialise, dans un delai qui n'excede pas quelques heures. Le memoire decrit le materiel de mesure et de prelevement, ainsi que les conditions de transport et d

  4. Treatment of Radioactive Effluents at the Saclay Nuclear Research Centre; Traitement des Effluents Radioactifs au Centre d'Etudes Nucleaires de Saclay; 041e 0414 ; Tratamiento de los Efluentes Radiactivos en el Centro de Energia Nuclear de Saclay

    Energy Technology Data Exchange (ETDEWEB)

    Wormser, G. [Service de Controle des Radiations et de Genie Radioactif, Commissariat a l' Energie Atomique, Saclay (France)

    1960-07-01

    The Report Gives The Account Of Four Years' Experience In Operating The Treatment Plant For Effluents From The Saclay Nuclear Research Centre. It Contains Data Relating To The Origin, Volume And Treatment Of Waste. (author) [French] Ce rapport presente un bilan d'exploitation de l'installation de traitement des effluents du Centre d'etudes nucleaires de Saclay depuis quatre ans. On donne des chiffres concernant l'origine des residus, leur volume, leur traitement. (author) [Spanish] El autor hace un balance de explotacion de la instalacion de tratamiento de efluentes del centro de Saclay desde hace cuatro anos, dando las cifras correspondientes al origen de los residuos, a su volumen y a su tratamiento. (author) [Russian] V jetom dokumente podvoditsja itog chetyrehletnej jekspluatacii ustanovki po obrabotke zhidkih othotov v Centre jadernyh issledovanij v Sakle. V doklade privodjatsja dannye o proishozhdenii othodov, jh ob'eme i obrabotke. (author)

  5. Improvement of pressure-vessel surveillance of a PWR-power plant of the Societe d'Energie Nucleaire Franco-Belge des Ardennes (S.E.N.A.)

    International Nuclear Information System (INIS)

    Bevilacqua, A.; Lloret, R.; Riehl, R.

    1984-01-01

    This paper describes a new dosimetry, installed inside and outside the Pressure Vessel of CHOOZ Nuclear Power Plant of the Societe d'Energie Nucleaire Franco-Belge des Ardennes (S.E.N.A.), during its 1982-83 operation cycle. The inner dosimetry deals with a simulated capsule located under the reactor plate, and includes copper, nickel, iron, niobium, copper-cobalt, neptunium and uranium dosimeters. Its aim is to qualify the information given by the existing copper dosimetry. The spectrum used with these measurements is obtained by the 1 D ANISN Code and BIP-N 2 library. The outer dosimety is the fluence determination along the outer wall of the vessel. Two tubes, equiped by neutron dosimeters, seven meters long, were fixed along the vessel. On the median plane, the results are compared to a 2 D DOT transport calculation. Preliminary results are given which improve the vessel and specimens neutronic characterisation. (Auth.)

  6. Balance between automation and human actions in nuclear power plant operation. Results of international cooperation; Equilibre entre automatisation et action humaine dans la conduite des centrale nucleaires, resultats de la cooperation internationale

    Energy Technology Data Exchange (ETDEWEB)

    Sun, B [CEA Centre d' Etudes Nucleaires de Fontenay-aux-Roses, 92 (France). Dept. d' Analyse de Surete; Bastl, W [Gesellschaft fuer Reaktorsicherheit m.b.H. (GRS), Garching (Germany); Olmstead, R [Atomic Energy of Canada Ltd, Mississauga (Canada); Oudiz, A [Electric Power Research Inst., Palo Alto, CA (United States); Jenkinson, J [Nuclear Electric PLC, Gloucester (United Kingdom); Kossilov, A [International Atomic Energy Agency, Vienna (Austria)

    1990-07-01

    Automation has long been an established feature of power plants. In some applications, the use of automation has been the significant factor which has enabled plant technology to progress to its current state. Societal demands for increased levels of safety have led to greater use of redundancy and diversity and this, in turn, has increased levels of automation. However, possibly the greatest contributory factor in increased automation has resulted from improvements in information technology. Much recent attention has been focused on the concept of inherently safe reactors, which may simplify safety system requirements and information and control system complexity. The allocation of tasks between man and machine may be one of the most critical activity in the design of new nuclear plants and major retro-fits and it therefore warrants a design approach which is commensurate in quality with the high levels of safety and production performance sought from nuclear plants. Facing this climate, in 1989 the International Atomic Energy Agency (IAEA) formed an advisory group from member countries with extensive experience in nuclear power plant automation. The task of this group was to advise on the appropriate balance between manual and automatic actions in plant operation. (author) [French] L'automatisation a longtemps ete une caracteristique bien etablie des centrales nucleaires. Dans certaines applications, l'utilisation de l'automatisation a ete le facteur decisif qui a permis a la technologie des centrales de progresser jusqu'a son etat actuel. Les exigences de l'opinion publique en matiere de securite renforcee ont conduit a l'utilisation d'une plus grande redondance et a une plus grande diversification et ceci, en retour, a encore accru le niveau d'automatisation. Toutefois, il est possible que le facteur preponderant de cet accroissement de l'automatisation soit constitue par les progres effectues dans la technologie de l'information. Plus recemment, l'attention s

  7. Irradiation and development of the nuclear emulsions exposed to intense fluxes of thermal neutrons with {gamma} rays; Irradiation et developpement des emulsions nucleaires exposees a des flux intenses de neutrons thermiques, accompagnes de rayons {gamma}

    Energy Technology Data Exchange (ETDEWEB)

    Faraggi, H; Bonnet, A; Cohen, J [Commissariat a l' Energie Atomique, Lab. du Fort de Chatillon, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

    1952-07-01

    The thermal neutron fluxes provided by nuclear reactors permit the survey of relatively rare phenomenons, and dosage of very weak quantities of some elements. One of the most favorable detection technique are constituted by the use of the nuclear emulsions. one can mention: - the dosage of uranium by counting in the emulsion the number of traces due to fission fragments after irradiation. - The dosage of the lithium and the boron as trace amounts with the help of nuclear reactions (n, {alpha}) and thermal neutrons. - The research of reactions (n, {alpha}) or (n, p) of very weak cross section for middle or heavy elements. These different applications require however important neutrons fluxes. It had therefore obliged us to search for the most favorable irradiation and development of the emulsions conditions, to get the best visibility of the trajectories and decrease the phenomena of fog on the emulsion, which prevents any observation. (M.B.) [French] Les flux de neutrons thermiques fournis par les reacteurs nucleaires permettent l'etude de phenomenes relativement rares, et le dosage de tres faibles quantites de certains elements. Un des moyens de detection les plus favorables est constitue par l'utilisation des emulsions nucleaires. on peut citer: - le dosage de l'uranium par comptage dans l'emulsion du nombre de traces dues aux fragments de fission apres irradiation. - Le dosage du lithium et du bore a l'etat de traces a l'aide des reactions (n, {alpha}) sous l'action des neutrons thermiques. - La recherche de reactions (n,{alpha}) ou (n,p) de tres faible section efficace pour des elements moyens ou lourds. Ces differentes applications necessite cependant des flux de neutrons important. On a donc ete amene a rechercher les conditions les plus favorables d'irradiation et de developpement des emulsions, de maniere a obtenir la meilleure visibilite des trajectoires et diminuer les phenomenes de voile de l'emulsion, qui empeche toute observation. (M.B.)

  8. Quantitative measurements of small isotopic samples in gaseous mixtures by utilization of some nuclear properties; Etude des possibilites de mesures de faibles quantites de gaz radioactifs dans un melange en utilisant simultanement plusieurs proprietes nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Maragnon, J; Delperie, C

    1967-12-01

    The question is to define the characteristics of a group of measurements allowing the analysis of traces of radioactive rare gases in gas mixtures of different composition. To distinguish the radioactive isotopes from each other and the activity level reaching 10{sup 6} due to their nuclear properties, the method was chosen to use several nuclear properties: gamma radiation energy, beta particle energy, lifetime of excited states. The choice of a plastic scintillator as beta detector allows to answer satisfactorilly to this demand by measurement of nuclear constants because of the short de/excitation time of this detector. Another advantage is that it can be a reservoir for the sample without any destruction nor modification of the sample. The study has been based on the mixture of Kr-85, the analysis of other rare gases follwos immediately from the adopted principle. [French] Les auteurs ont oriente leur recherche vers une solution permettant de distinguer les isotopes radioactifs les uns des autres et dans des rapports d'activite pouvant atteindre 10{sup 6}, grace a plusieurs de leurs proprietes nucleaires, energie de rayonnement gamma, energie de la particule beta, temps de vie des niveaux excites. Le choix d'un scintillateur plastique comme detecteur beta permet de repondre d'une maniere satisfaisante a la mesure des constantes nucleaires en raison du temps de de/excitation rapide de ce scintillateur. Il offre en outre l'avantage de pouvoir servir de reservoir a l'echantillon sans entrainer aucune destruction ni modification de celui-ci. L'etude a ete basee sur la mixture de Kr-85, l'analyse des autre gaz rares decoulant immediatement du principe adopte. (auteur)

  9. Health physics problems in the context of the development of industrial uses of nuclear energy; Les problemes de radioprotection devant le developpement de l'utilisation industrielle de l'energie nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Duhamel, F.; Menoux, A. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-07-01

    fate of radioactive ions in the hydrosphere may be determined. - experiments and studies linked with the possibilities for disposal a underground storage of wastes. All these studies cover a complementary field, that of radioprotection, which forms the necessary link between nuclear safety proper, which concerns the actual operation of nuclear installations and medical supervision which directly concerns the health of the individual and the population. At the same time each one of the Health Physics disciplines possesses an independence which increases their efficiency on the safety level. (authors) [French] Le developpement de l'utilisation industrielle de l'energie nucleaire a mis l'accent sur la necessite de promouvoir une doctrine rationnelle et coherente en matiere de securite des installations atomiques et plus particulierement en matiere de securite des sites nucleaires. Le but principal de la securite est de diminuer, voire d'annuler les risques d'irradiation ou de contamination des travailleurs et de la population, consecutifs au fonctionnement normal ou accidentel des installations. La securite est obtenue par la mise en oeuvre d'un ensemble complexe de moyens. Parmi ces moyens les auteurs considerent essentiellement ceux qui presentent une certaine independance a l'egard du type d'installation: moyens d'alerte et de mesure et leur mise en oeuvre - preparation psychologique et technique des individus - evaluation de la capacite d'un site a absorber les rejets radioactifs sans dommage pour la population. Il est clair en effet que les consequences d'un accident sont diminuees par l'augmentation de la valeur des moyens de surveillance, de mesure et d'alerte, l'elevation du niveau technique et l'entrainement du personnel, l'education de la population. Ceci est particulierement vrai aupres d'une installation nucleaire ou l'etude des dangers presente un caractere abstrait et

  10. Health physics problems in the context of the development of industrial uses of nuclear energy; Les problemes de radioprotection devant le developpement de l'utilisation industrielle de l'energie nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Duhamel, F; Menoux, A [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-07-01

    fate of radioactive ions in the hydrosphere may be determined. - experiments and studies linked with the possibilities for disposal a underground storage of wastes. All these studies cover a complementary field, that of radioprotection, which forms the necessary link between nuclear safety proper, which concerns the actual operation of nuclear installations and medical supervision which directly concerns the health of the individual and the population. At the same time each one of the Health Physics disciplines possesses an independence which increases their efficiency on the safety level. (authors) [French] Le developpement de l'utilisation industrielle de l'energie nucleaire a mis l'accent sur la necessite de promouvoir une doctrine rationnelle et coherente en matiere de securite des installations atomiques et plus particulierement en matiere de securite des sites nucleaires. Le but principal de la securite est de diminuer, voire d'annuler les risques d'irradiation ou de contamination des travailleurs et de la population, consecutifs au fonctionnement normal ou accidentel des installations. La securite est obtenue par la mise en oeuvre d'un ensemble complexe de moyens. Parmi ces moyens les auteurs considerent essentiellement ceux qui presentent une certaine independance a l'egard du type d'installation: moyens d'alerte et de mesure et leur mise en oeuvre - preparation psychologique et technique des individus - evaluation de la capacite d'un site a absorber les rejets radioactifs sans dommage pour la population. Il est clair en effet que les consequences d'un accident sont diminuees par l'augmentation de la valeur des moyens de surveillance, de mesure et d'alerte, l'elevation du niveau technique et l'entrainement du personnel, l'education de la population. Ceci est particulierement vrai aupres d'une installation nucleaire ou l'etude des dangers presente un caractere abstrait et ou les moyens technologiques de protection sont multiples et complexes. Les etudes de

  11. A study of the fluorescence of the rare gases excited by nuclear particles. Use of the principle for the detection of nuclear radiation by scintillation; Etude de la fluorescence des gaz rares excites par des particules nucleaires. Utilisation pour la detection des rayonnements nucleaires par scintillation

    Energy Technology Data Exchange (ETDEWEB)

    Koch, L [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1959-12-15

    composantes, l'une tres breve due a la desexcitation directe du gaz rare, l'autre relativement plus lente, due au transfert d'energie sur les impuretes. La mesure des durees de vie des etats excites a confirme l'hypothese precedente, la partie breve de l'impulsion est extremement courte: inferieure a 2,25.10{sup -9} s dans le cas du xenon, la partie plus lente a une duree qui depend etroitement de la concentration d'azote, l'azote etant l'impurete dont le role est preponderant dans tous les cas. L'etude des gaz rares soumis a un champ electrique a permis de montrer que la quantite de lumiere produite par une particule {alpha} peut etre multipliee (par 60 dans un champ de 600 V/cm par exemple) ce qui correspond a un rendement de luminescence superieur a celui de INa TI. Dans la deuxieme partie on a etudie les caracteristiques des gaz rares comme scintillateurs, la plus importante est l'absence de saturation de la fluorescence lorsque la densite d'excitation transmise au gaz devient tres grande. Ceci joint au temps de scintillation tres court a permis d'etudier un certain nombre d'applications a la physique nucleaire (mesure d'energie des particules lourdes, etude cinetique des reacteurs nucleaires, spectroscopie des neutrons...). (auteur)

  12. Economic Criteria Applied to Nuclear Materials Management; Criteres Economiques Applicables a la Gestion des Matieres Nucleaires; Ehkonomicheskie kriterii, primenyaemye pri kontrole i uchete yadernykh materialov; Criterios Economicos Aplicados a la Administracion de Materiales Nucleares

    Energy Technology Data Exchange (ETDEWEB)

    Shelley, W. J.; Kuehn, M. N. [Mallinckrodt Chemical Works, St. Charles, MS (United States)

    1966-02-15

    placed upon such personnel to accept, understand and perform the work. Such personnel selected must be thoroughly and minutely trained in the importance of their activity. Those responsible for the management of nuclear materials must be continually alert to the smallest kind of aberration in the quality and performance of the personnel, the process, the systems, procedures and techniques. Only through such alertness and willingness to revise, so as to secure improvement, does one secure the optimum balance of costs and needs. (author) [French] La gestion des matieres nucleaires doit etre subordonnee aux objectifs principaux du traitement de ces matieres, c'est-a-dire la production d'energie ou la fabrication de produits finis. Les responsables de la gestion des matieres nucleaires doivent donc tenir constamment compte des besoins de la production principale et adapter les methodes de gestion aux operations de facon a pouvoir assurer cette gestion avec un minimum de depenses. Le systeme de gestion des matieres nucleaires doit soigneusement tenir compte des divers facteurs qui influent sur son prix de revient. Il vient en complement des operations et doit entrainer le minimum de frais de personnel et d'analyse et provoquer le moins d'interruptions possible dans les operations. U doit etre integre a ces dernieres, de facon que les renseignements d'ordre quantitatif qu'il permet d'obtenir puissent etre communiques rapidement aux responsables du controle des operations. Le systeme d'enregistrement et de preparation des rapports doit fournir une quantite maximale de donnees subsidiaires. Il doit etre compatible avec les systemes utilises par les fournisseurs et les consommateurs et assurer la diffusion, partout ou cela est possible, de renseignements supplementaires concernant les lots de matieres nucleaires. Les donnees a fournir pour le controle des matieres nucleaires doivent se limiter a celles qui sont necessaires pour s'assurer qu'il n'y a pas de pertes importantes, de

  13. A Mosaic Expression of a Hb J-Amiens (HBB: c.54G > T; p.Lys18Asn) and its Interference with Hb A1c Analysis.

    Science.gov (United States)

    Schiemsky, Toon; Van Hoovels, Lieve; Desmet, Koen J O; Phylipsen, Marion; Harteveld, Cornelis L; Kieffer, Davy M J

    2015-01-01

    We report the case of a 56-year-old Caucasian woman in whom hemoglobinopathy screening was triggered following an aberrant Hb A1c analysis. Preliminary diagnosis of the hemoglobin (Hb) variant was obtained through cation exchange high performance liquid chromatography (HPLC) and gel electrophoresis. DNA analysis confirmed the presence of Hb J-Amiens [β17(A14)Lys→Asn; HBB: c.[54G > C or 54G > T)]. However, an unbalanced ratio between wild type and mutant signal after direct sequencing and a lower than expected percentage of this Hb variant led to the suggestion of a mosaic expression. Furthermore, different methods [capillary zone electrophoresis (CZE), cation exchange HPLC and boronate affinity] were tested to study the possible interference of this variant with Hb A1c measurements. These investigations showed a clinically relevant difference between the methods tested. Hb A1c analysis may lead to the discovery of new Hb variants or mosaicism for previously described Hb variants. This may have genetic consequences for the offspring of carriers and brings about the question of partner testing.

  14. How can the population be brought to accept a probable (inevitable?) accident? the point of view of an N.G.O., 'Groupement de Scientifiques pour l'Information sur l'Energie Nucleaire'

    International Nuclear Information System (INIS)

    Sene, M.

    2008-01-01

    What contribution can an association make to the deliberations of a working group on the management of post-nuclear accident situations set up by ASN? Attempt to convey an understanding of the difficulty of building a dialogue capable of leading to citizen participation. How can the CLIs (local information committees) be included in this process and optimum use made of their pluralism and their local roots? Attempt to build this participation, defining its limits and explaining its needs: access to documents, expert resources, etc. The difficulty will be to sustain this participation and find successors. (author)

  15. The old and the new in prekallikrein deficiency: historical context and a family from Argentina with PK deficiency due to a new mutation (Arg541Gln) in exon 14 associated with a common polymorphysm (Asn124Ser) in exon 5.

    Science.gov (United States)

    Girolami, Antonio; Vidal, Josè; Sabagh, Marcela; Salagh, Marcela; Gervan, Nora; Parody, Maria; Peroni, Edoardo; Sambado, Luisa; Guglielmone, Hugo

    2014-07-01

    Prekallikrein (PK) is one of the clotting factors involved in the contact phase of blood. PK has an important historical role as its deficiency state represents the second instance of a clotting defect without bleeding manifestations, the first one being factor XII deficiency. PK deficiency is a rare clotting disorder. Moreover, only 11 patients have been investigated so far by molecular biology techniques. In this article, we briefly review some of the history around PK and also present some recent data on a newly identified family from Argentina suffering from PK deficiency. Two patients are homozygous whereas other family members are heterozygous. PK activity and antigen are 1% of normal in the homozygotes and around 60 to 70% of normal in the heterozygotes. As expected, all patients are asymptomatic of bleeding or thrombosis presentations. However, the two homozygotes showed essential hypertension. The PK deficiency in this family is due to a new mutation (Arg541Gln) in exon 14. The defect segregates together with a known polymorphism, Asn124Ser, in exon 5. The significance of the presence of hypertension in the two homozygotes is discussed in view of the extra coagulation effects of PK on vasodilation, vessel permeability, and the control of blood pressure. Structure function analysis indicates that the substitution of Arg with Gln probably impedes the transmembrane diffusion of the molecule, which therefore cannot be secreted in the homozygotes. The presence of hypertension in patients with PK deficiency has been previously reported in some but not all patients. Future research activities will probably concentrate on the effect of PK and other contact phase factors on the vascular system. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  16. α-Thalassemia Associated with Hb Instability: A Tale of Two Features. The Case of Hb Rogliano or α1 Cod 108(G15)Thr→Asn and Hb Policoro or α2 Cod 124(H7)Ser→Pro.

    Science.gov (United States)

    Musollino, Gennaro; Cardiero, Giovanna; Flagiello, Angela; La Porta, Gaetana; Lagona, Laura; Prezioso, Romeo; Qualtieri, Gabriele; Gaudiano, Carlo; Medulla, Emilia; Merlino, Antonello; Pucci, Piero; Lacerra, Giuseppina

    2015-01-01

    We identified two new variants in the third exon of the α-globin gene in families from southern Italy: the Hb Rogliano, α1 cod108 ACC>AAC or α1[α108(G15)Thr→Asn] and the Hb Policoro, α2 cod124 TCC>CCC or α2[α124(H7)Ser→Pro]. The carriers showed mild α-thalassemia phenotype and abnormal hemoglobin stability features. These mutations occurred in the G and H helices of the α-globin both involved in the specific recognition of AHSP and β1 chain. Molecular characterization of mRNA, globin chain analyses and molecular modelling studies were carried out to highlight the mechanisms causing the α-thalassemia phenotype. The results demonstrated that the α-thalassemia defect associated with the two Hb variants originated by different defects. Hb Rogliano showed an intrinsic instability of the tetramer due to anomalous intra- and inter-chain interactions suggesting that the variant chain is normally synthesized and complexed with AHSP but rapidly degraded because it is unable to form the α1β1 dimers. On the contrary in the case of Hb Policoro two different molecular mechanisms were shown: the reduction of the variant mRNA level by an unclear mechanism and the protein instability due to impairment of AHSP interaction. These data highlighted that multiple approaches, including mRNA quantification, are needed to properly identify the mechanisms leading to the α-thalassemia defect. Elucidation of the specific mechanism leads to the definition of a given phenotype providing important guidance for the diagnosis of unstable variants. PMID:25730315

  17. Contribution to the study of the evolution of radiation induced He in Be O; Etudes sur l'evolution de l'helium produit par reactions nucleaires dans l'oxyde de beryllium

    Energy Technology Data Exchange (ETDEWEB)

    Bareau, J [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1966-11-15

    The purpose of this work in-pile investigation of He formed by (n, 2n) and (n, {alpha}) nuclear reactions, released from irradiated BeO, in the temperature range 1000 - 1350 deg. C. The experimental results show that, for an instantaneous neutron fast flux of 10{sup 13} n cm{sup -2} sec{sup -1}, an equilibrium is attempted, after several days, for a part lower than 20 per cent of the quantity of He formed, theoretically calculated from the neutron cross sections of nuclear reactions, and from the analytical form of the neutron fast flux, releases from the solid. The validity of the values of calculated helium and the gas chromatographic analytical method are also verified by dissolution of the BeO pellets in cryolite. A new fast neutron flux measuring method may be so defined. The discussion of the experimental results enables to establish that the processus of He release is characterized by two phenomena: the first one which controls the release of He atoms out of the solid and the second which reveals a capture processus, connected to the irradiation and probably due to the vacancies induced in the lattice. (author) [French] On etudie en pile le degagement de l'helium forme par reactions nucleaires (n, 2 n) et (n, {alpha}) dans l'oxyde de beryllium irradie entre 1000 et 1350 deg. C. Les resultats experimentaux montrant que, pour un flux rapide instantane de 10{sup 13} n{sub r} cm{sup -2} s{sup -1}, on aboutit, au bout de quelques jours, a un etat d'equilibre pour lequel une partie, inferieure a 20 pour cent de la quantite d'helium forme, calculee theoriquement a partir des sections efficaces des reactions nucleaires et de la forme analytique du flux rapide, s'echappe du solide. On verifie egalement par dissolution des echantillons de BeO dans la cryolithe la validite du calcul de l'helium et de la methode de dosage par chromatographie en phase gazeuse. On peut ainsi definir une methode nouvelle de mesure des flux rapides. La discussion des resultats experimentaux

  18. Contribution to the study of the evolution of radiation induced He in Be O; Etudes sur l'evolution de l'helium produit par reactions nucleaires dans l'oxyde de beryllium

    Energy Technology Data Exchange (ETDEWEB)

    Bareau, J. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1966-11-15

    The purpose of this work in-pile investigation of He formed by (n, 2n) and (n, {alpha}) nuclear reactions, released from irradiated BeO, in the temperature range 1000 - 1350 deg. C. The experimental results show that, for an instantaneous neutron fast flux of 10{sup 13} n cm{sup -2} sec{sup -1}, an equilibrium is attempted, after several days, for a part lower than 20 per cent of the quantity of He formed, theoretically calculated from the neutron cross sections of nuclear reactions, and from the analytical form of the neutron fast flux, releases from the solid. The validity of the values of calculated helium and the gas chromatographic analytical method are also verified by dissolution of the BeO pellets in cryolite. A new fast neutron flux measuring method may be so defined. The discussion of the experimental results enables to establish that the processus of He release is characterized by two phenomena: the first one which controls the release of He atoms out of the solid and the second which reveals a capture processus, connected to the irradiation and probably due to the vacancies induced in the lattice. (author) [French] On etudie en pile le degagement de l'helium forme par reactions nucleaires (n, 2 n) et (n, {alpha}) dans l'oxyde de beryllium irradie entre 1000 et 1350 deg. C. Les resultats experimentaux montrant que, pour un flux rapide instantane de 10{sup 13} n{sub r} cm{sup -2} s{sup -1}, on aboutit, au bout de quelques jours, a un etat d'equilibre pour lequel une partie, inferieure a 20 pour cent de la quantite d'helium forme, calculee theoriquement a partir des sections efficaces des reactions nucleaires et de la forme analytique du flux rapide, s'echappe du solide. On verifie egalement par dissolution des echantillons de BeO dans la cryolithe la validite du calcul de l'helium et de la methode de dosage par chromatographie en phase gazeuse. On peut ainsi definir une methode nouvelle de mesure des flux rapides. La

  19. Study methods for the drillings around the underground nuclear explosions in the Sahara. Part 1. study of rock samples; Methodes d'etude des forages realises autour des explosions nucleaires souterraines au Sahara. Premiere partie: etude des echantillons de roche

    Energy Technology Data Exchange (ETDEWEB)

    Derlich, S [Commissariat a l' Energie Atomique, Bruyers-le-Chatel (France). Centre d' Etudes

    1969-07-01

    An examination of the mechanical effects produced on rocks by an underground nuclear explosion calls for the use of particular means of exploration which are described in this report, special attention being paid to the equipment used in connection with the French nuclear tests in the Sahara. The drilling methods used (rotary and turbo-drilling) are adapted to the particular conditions of the sampling programme, to the radioactivity and to the temperature in the region of the explosion. A study of the samples makes it possible to obtain the new characteristics of the rock and to assess the chemical and mechanical transformations which it has undergone. An examination of the core obtained from the drilling, together with a knowledge of the drilling parameters (depth of the probe, sample recovery, etc...), makes it possible to study the extent and the characteristics of the zones which have been damaged to different degrees according to their distance from the zero point: cavity, strongly powdered zone, fractured zone, chimney, zones containing high stresses leading to a particular type of fracture of the cores. The problems connected with the interpretation of the results are also presented. (author) [French] L'examen des effets mecaniques provoques par une explosion nucleaire souterraine sur la roche necessite la mise en oeuvre de moyens d'exploration particuliers dont l'expose fait l'objet de ce rapport, essentiellement pour les moyens utilises autour des essais nucleaires francais au Sahara. Les methodes de forage (rotary et turboforage) sont adaptees aux conditions particulieres dues au programme d'echantillonnage, a la radioactivite et a la temperature regnant a proximite du point de tir. L'etude des echantillons permet la determination des nouveaux caracteres de la roche et de ses transformations chimique et mecanique. L'examen des carottes et l'utilisation des parametres de forage (cotes sondeurs, recuperation des echantillons, etc...) permettent d'etudier l

  20. Irradiation and development of the nuclear emulsions exposed to intense fluxes of thermal neutrons with {gamma} rays; Irradiation et developpement des emulsions nucleaires exposees a des flux intenses de neutrons thermiques, accompagnes de rayons {gamma}

    Energy Technology Data Exchange (ETDEWEB)

    Faraggi, H.; Bonnet, A.; Cohen, J. [Commissariat a l' Energie Atomique, Lab. du Fort de Chatillon, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

    1952-07-01

    The thermal neutron fluxes provided by nuclear reactors permit the survey of relatively rare phenomenons, and dosage of very weak quantities of some elements. One of the most favorable detection technique are constituted by the use of the nuclear emulsions. one can mention: - the dosage of uranium by counting in the emulsion the number of traces due to fission fragments after irradiation. - The dosage of the lithium and the boron as trace amounts with the help of nuclear reactions (n, {alpha}) and thermal neutrons. - The research of reactions (n, {alpha}) or (n, p) of very weak cross section for middle or heavy elements. These different applications require however important neutrons fluxes. It had therefore obliged us to search for the most favorable irradiation and development of the emulsions conditions, to get the best visibility of the trajectories and decrease the phenomena of fog on the emulsion, which prevents any observation. (M.B.) [French] Les flux de neutrons thermiques fournis par les reacteurs nucleaires permettent l'etude de phenomenes relativement rares, et le dosage de tres faibles quantites de certains elements. Un des moyens de detection les plus favorables est constitue par l'utilisation des emulsions nucleaires. on peut citer: - le dosage de l'uranium par comptage dans l'emulsion du nombre de traces dues aux fragments de fission apres irradiation. - Le dosage du lithium et du bore a l'etat de traces a l'aide des reactions (n, {alpha}) sous l'action des neutrons thermiques. - La recherche de reactions (n,{alpha}) ou (n,p) de tres faible section efficace pour des elements moyens ou lourds. Ces differentes applications necessite cependant des flux de neutrons important. On a donc ete amene a rechercher les conditions les plus favorables d'irradiation et de developpement des emulsions, de maniere a obtenir la meilleure visibilite des trajectoires et diminuer les phenomenes de voile de l'emulsion, qui

  1. Nuclear Materials Management and its Relationship to Nuclear Safety and Criticality Control; La Gestion des Matieres Nucleaires et ses Rapports avec la Securite Nucleaire et le Controle de la Criticite; Obrashchenie s yadernymi materialami i ego svyaz' s yadernoj bezopasnost'yu i kontrolem nad kritichnost'yu; La Administracion de Materiales Nucleares y sus Relaciones con la Seguridad Nuclear y el Control de la Criticidad

    Energy Technology Data Exchange (ETDEWEB)

    Tingey, F. H. [Phillips Petroleum Company, Idaho Falls, ID (United States)

    1966-02-15

    dictated by the technical considerations and familiar with the operational limitations. The administrative problems are solved through procedural restrictions placed by the supervisor. The NMM office can be most valuable in further support to the supervisor in these activities. The primary responsibility of this office is to alert responsible supervision to potentially hazardous situations as indicated either from information made available through the routine processing of accountability data or from material balance calculations. Any information pertaining to criticality studies as requested from the NMM office must be accurate and precise. A vigorous inventory management policy must be pursued to lessen the problems presented by accumulation of fissile materials. Internal audit by the NMM staff of inventory holdings can also serve to verify adherence to safeguard procedures. A vigorous orientation programme can be implemented by the NMM staff in its dealing with those individuals handling nuclear materials to make them more aware of the hazards involved. The integration of the NMM group into the general criticality safeguard problems at the NRT and has provided an effective system for assisting the line supervision in discharging this very important responsibility. (author) [French] Il est essentiel pour tous ceux qui travaillent dans l'industrie nucleaire de savoir comment eviter que des matieres nucleaires ne se trouvent rassemblees en quantites, selon une geometrie ou dans un milieu tels qu'elles puissent donner lieu a une reaction neutronique en chaine. Ceci interesse tout particulierement ceux qui, dans l'exercice de leurs fonctions, sont responsables de la manipulation, du transfert et de l'entreposage des matieres fissiles. Ces memes personnes participent au systeme de gestion des matieres nucleaires. Elles ont au premier chef la responsabilite de fournir et de recevoir les donnees comptables par l'intermediaire du service de gestion des matieres nucleaires

  2. Nuclear medicine. La medecine nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Blanquet, P; Blanc, D

    1976-01-01

    The applications of radioisotopes in medical diagnostics are briefly reviewed. Each organ system is considered and the Nuclear medicine procedures pertinent to that system are discussed. This includes, the principle of the test, the detector and the radiopharmaceutical used, the procedure followed and the clinical results obtained. The various types of radiation detectors presently employed in Nuclear Medicine are surveyed, including scanners, gamma cameras, positron cameras and procedures for obtaining tomographic presentation of radionuclide distributions.

  3. Fluctuations in a system depending on several random parameters. Application to reactors (1962); Fluctuations d'un systeme dependant de plusieurs parametres aleatoires. Application aux reacteurs nucleaires (1962)

    Energy Technology Data Exchange (ETDEWEB)

    Blaquiere, A [Faculte des Sciences de Paris, 75 (France); Pachowska, R [Universite Technique de Varsovie (Poland)

    1962-07-01

    We have previously developed a method for studying neutronic fluctuations in nuclear reactors using the analogy between the behaviour of a reactor and that of certain common radioelectric circuits. The fluctuations may then be calculated by introducing into the circuit a suitable noise source. By this method we have been able to consider the overall fluctuations in a particularly simple form and we have provided a physical significance for certain results obtained more laboriously by other methods. The object of the present report is to generalise this method and in particular to extend it to the case of a reactor having a cellular structure and to apply it to fluctuations within a cell. It is thus shown that the fluctuations in a cell are the resultant of two terms: - a rapidly evolving Poissonian noise, not related to the overall fluctuations; - a slowly evolving noise, when the reactor is not too far from criticality, which is related to the overall fluctuations. The first term arises from a rapid 'ordering' of the system, during which time the cells come mutually into equilibrium. The second term is due to the coordinated evolution of all the cells, after the end of the first transitory phase. The conclusions reached show that it would be useful to complete the study with an analysis of non-linear phenomena which can considerably influence the transitory behaviour of the cells during the initial pre-equilibrium phase. This report also Stresses the relationship of the new method to the old methods. It tends also to place pile fluctuation theory in a more general framework, that of the fluctuations of a system depending on several random parameters; from this point of view, the method could easily be transposed and adapted to the study of other physical problems of this type. (authors) [French] Nous avons precedemment developpe une methode d'etude des fluctuations neutroniques des reacteurs nucleaires mettant a profit l'analogie entre le comportement d

  4. Contribution to the study of radio toxicity of aromatic and medicinal plants using solid state nuclear track detectors; Contribution a l etude de la radio toxicite des plantes aromatiques et medicinales au moyen des detecteurs solides de traces nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Mortassim, A; Misdaq, M A; Naaman, A

    2009-07-01

    The concentrations of uranium (238 U), thorium (232 Th), radon (222 Rn) and thoron (220 Rn) were measured in twenty aromatic and medicinal plants in {sup f}ind a new method based on using solid state nuclear track detectors type Cr-39 and Rs-115. He emerges from this study that the verbena and salvia have higher levels of uranium (radon) higher than that of other plants while the leaves of olive and saturja have concentrations of thorium (thoron) higher than other plants therefore radio toxicity of these plants is higher than that of others and may pose a radiological hazard if the masses are incorporated by consumers high. [French] Les concentrations en uranium (238U), thorium (232Th), radon (222Rn), et thoron (220Rn) ont ete mesurees dans vingt plantes aromatiques et medicinales en utilsant une nouvelle methode basee sur l utilisation des detecteurs solides de traces nucleaires de types CR-39 et LR-115. Il en sort de cette etude que la verveine et la salvia presentent des teneurs en uranium (radon) superieurs a celle des autres plantes alors que les feuilles d olivier et la saturja presentent des concentrations en thorium (thoron) plus elevee que celles des autres plantes par consequent la radio toxicite de ces plantes est superieure a celles des autres et peuvent presenter un risque radiologique si les masses incorporees par les consommateurs sont elevees.

  5. Integration of the nuclear energy among the production facilities of energy in France; Integration de l'energie nucleaire parmi les moyens de production de l'energie en france

    Energy Technology Data Exchange (ETDEWEB)

    Ailleret, P [Electricite de France (EDF), 75 - Paris (France). Direction des Etudes et Recherches; Taranger, P [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1955-07-01

    The present report gives an overview of the present facilities of energy productions in France and their perspectives. the electric production comes for half about power stations hydraulics and for half of thermal power stations. However due to the increase of the energy consumption, France is particularly interested by the atomic energy that appears to bring a supply in due time to the hydraulics and to limit a development of the thermal power stations to which the natural resources of France in classic fuel would not permit to cope presumably. The integration of the nuclear plants to the other production facilities will make itself gradually according to the evolution of the energy needs. (M.B.) [French] Le present rapport donne un apercu des moyens actuels de productions energetiques en France et de ses perspectives. la production electrique provient pour moitie environ de centrales hydraulique et pour moitie de centrales thermiques. Cependant face a l'augmentation de la consommation energetique, la France est tres particulierement interessee par l'energie atomique qui parait devoir apporter en temps utile la releve a l'hydraulique et limiter un developpement des centrales thermiques auxquels les ressources naturelles de la France en combustible classique ne permettraient vraisemblablement pas de faire face. L'integration des centrales nucleaires aux autres moyens de production se fera graduellment en fonction de l'evolution des besoins energetiques. (M.B.)

  6. Contribution to the study of the action of electromagnetic fields on the angular correlations of nuclear radiation (1960); Contribution a l'etude de l'action des champs electromagnetiques sur les correlations angulaires des rayonnements nucleaires (1960)

    Energy Technology Data Exchange (ETDEWEB)

    Lehmann, P [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1959-01-15

    This work deals with the study of interaction of E.M. fields with nuclear moments of nuclei emitting gamma rays. We describe first experiments on delayed angular correlation showing the role played by statistic quadrupole interaction. We have measured the magnetic moment of the second excited state of {sup 19}F using an external magnetic field. In the case of {sup 19}O, experiments of angular distributions and angular correlations of gamma -rays taking into account the possibility of perturbations, allow us to determine the spin and parities of the three first levels. (author) [French] Le present travail concerne l'etude de l'interaction des champs electromagnetiques et des moments nucleaires de noyaux emettant des rayonnements gamma. Nous decrivons des experiences de correlation angulaire differee dont l'interpretation met en coincidence le role joue par les interactions quadrupolaires statiques. Nous avons mesure le moment magnetique de {sup 19}F dans un etat excite en utilisant un champ magnetique exterieur a la source radioactive. Enfin, dans le cas de {sup 19}O, nous montrons l'utilite d'un examen des possibilites de perturbations dans l'interpretation des resultats fournis par des correlations ou des distributions angulaires. (auteur)

  7. Study relating to the physico-chemical behaviour of heavy water in nuclear reactors; Etudes relatives au comportement physico-chimique de l'eau lourde dans les reacteurs nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Chenouard, J; Dirian, G; Roth, E; Vignet, P; Platzer, R [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1959-07-01

    Chemical and isotope pollution, and radiolytic decomposition are the two most important ways in which heavy water becomes degraded in nuclear reactors. Chemical pollution has led to the creation of ion exchange purification loops specially designed for reactors: the report contains a description in detail of the application of this purification method in CEA research reactors, including the analysis required, results obtained, and their interpretation. The intelligence obtained on radiolytic decomposition with the same facilities is also discussed, as well as the recombination apparatus and control equipment utilized. Finally, investigation to date in the CEA on recombination circuits for power reactors is also discussed. (author) [French] Parmi les degradations subies par l'eau lourde dans les reacteurs nucleaires, les deux plus importantes sont la pollution chimique et isotopique et la decomposition radiolytique. La pollution chimique a conduit a mettre au point pour le cas particulier des reacteurs, des circuits d'epuration par echange d'ions. On decrit ici en detail la mise en oeuvre de cette methode dans les reacteurs de recherche du CEA; les controles qu'elle necessite, les resultats obtenus et leur interpretation. En ce qui concerne la dissociation radiolytique de l'eau, les renseignements obtenus sur ces memes reacteurs sont communiques, ainsi que les details des dispositifs de recombinaison et des moyens de controle. Enfin, on fait le point des etudes poursuivies au CEA sur ces memes problemes de recombinaison dans le cas des reacteurs de puissance. (auteur)

  8. Chemical elimination of alumina in suspension in nuclear reactors heavy water; Elimination de l'alumine en suspension dans l'eau lourde des reacteurs nucleaires par voie chimique

    Energy Technology Data Exchange (ETDEWEB)

    Ledoux, A [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1967-02-01

    Corrosion of aluminium in contact with moderating water in nuclear reactor leads to the formation of an alumina hydrosol which can have an adverse effect on the operation of the reactor. Several physical methods have been used in an attempt to counteract this effect. The method proposed here consists in the elimination of the aluminium by dissolution and subsequent fixation in the ionic form on mixed-bed ion-exchange resin. In order to do this, the parameters and the values of these parameters most favorable to the dissolution process have been determined. If the moderator is heavy water, the deuterated acid can be prepared by converting a solution in heavy water to a salt of the acid using a deuterated cationic resin. (author) [French] La corrosion de l'aluminium au contact de l'eau moderatrice des reacteurs nucleaires, donne lieu a la formation d'un hydrosol d'alumine nuisible au bon fonctionnement des reacteurs. Plusieurs methodes physiques ont ete mises en oeuvre pour pallier ces inconvenients. On propose ici d'eliminer l'alumine par solubilisation pour la fixer ensuite sous forme ionique par des resines echangeuses d'ions, en lit melange. A cette fin on determine les parametres et leurs grandeurs favorables a cette solubilisation. Si le moderateur est de l'eau lourde la preparation d'acide deutere peut etre effectuee par passage d'une solution en eau lourde a un sel de l'acide sur resine cationique deuteree.

  9. Study relating to the physico-chemical behaviour of heavy water in nuclear reactors; Etudes relatives au comportement physico-chimique de l'eau lourde dans les reacteurs nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Chenouard, J.; Dirian, G.; Roth, E.; Vignet, P.; Platzer, R. [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1959-07-01

    Chemical and isotope pollution, and radiolytic decomposition are the two most important ways in which heavy water becomes degraded in nuclear reactors. Chemical pollution has led to the creation of ion exchange purification loops specially designed for reactors: the report contains a description in detail of the application of this purification method in CEA research reactors, including the analysis required, results obtained, and their interpretation. The intelligence obtained on radiolytic decomposition with the same facilities is also discussed, as well as the recombination apparatus and control equipment utilized. Finally, investigation to date in the CEA on recombination circuits for power reactors is also discussed. (author) [French] Parmi les degradations subies par l'eau lourde dans les reacteurs nucleaires, les deux plus importantes sont la pollution chimique et isotopique et la decomposition radiolytique. La pollution chimique a conduit a mettre au point pour le cas particulier des reacteurs, des circuits d'epuration par echange d'ions. On decrit ici en detail la mise en oeuvre de cette methode dans les reacteurs de recherche du CEA; les controles qu'elle necessite, les resultats obtenus et leur interpretation. En ce qui concerne la dissociation radiolytique de l'eau, les renseignements obtenus sur ces memes reacteurs sont communiques, ainsi que les details des dispositifs de recombinaison et des moyens de controle. Enfin, on fait le point des etudes poursuivies au CEA sur ces memes problemes de recombinaison dans le cas des reacteurs de puissance. (auteur)

  10. The Staffing of Central Electricity Generating Board Nuclear Power Stations; Organigramme des centrales nucleaires du central electricity generating board; Politika v oblasti kadrov na atomnykh ehlektrostantsiyakh CEGB; El personal de las plantas nucleoelectricas de la central electricity generating board.

    Energy Technology Data Exchange (ETDEWEB)

    Bartlett, J. S.; Shepherd, G. T. [Central Electricity Generating Board, Western Division, Bristol (United Kingdom)

    1963-10-15

    An account is given of the staffing requirements and organization at a CEBG nuclear power station. The training of staff and licensing requirements for reactoroperating staff are discussed. Experience gained to data of the outcome of pre-operating training and detailed planning in the operational sphere is given. (author) [French] Le memoire donne un apercu de l'organigramme d'une centrale nucleaire du CEGB et des conditions auxquelles doit satisfaire le personnel (formation, qualifications requises pour la fonction d'operateur). Il rend compte egalement de l'experience acquise a ce jour quant a l'interet qu'il y a a former le personnel au prealable et a etablir des plans d'operation detailles. (author) [Spanish] La memoria informa sobre la organizacion de las centrales nucleoelectricas de la CEGB y sobre la plantilla de personal que estas requieren. Discute la formacion del personal y los requisitos para obtener la licencia de operador de reactores. Describe la experiencia adquirida hasta el presente en materia de formacion previa del personal y de organizacion detallada de las operaciones. (author) [Russian] Daetsya otchet o trebovaniyakh, pred{sup y}avlyaemykh k personalu, i organizatsiya nabora personala na atomnykh ehlektrostantsiyakh Tsentral'nogo upravleniya proizvodstva ehlektroehnergii (CEGB). Obsuzhdayutsya voprosy podgotovki personala i normativnykh trebovanij, pred{sup y}avlyaemykh k ehkspluatatsionnomu personalu. Izlagaetsya opyt, nakoplennyj k nastoyashchemu vremeni v rezul'tate osushchestvleniya predehkspluatatsionnoj podgotovki i podrobnogo planirovaniya v usloviyakh ehkspluatatsii. (author)

  11. Contribution to the study of the action of electromagnetic fields on the angular correlations of nuclear radiation (1960); Contribution a l'etude de l'action des champs electromagnetiques sur les correlations angulaires des rayonnements nucleaires (1960)

    Energy Technology Data Exchange (ETDEWEB)

    Lehmann, P. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1959-01-15

    This work deals with the study of interaction of E.M. fields with nuclear moments of nuclei emitting gamma rays. We describe first experiments on delayed angular correlation showing the role played by statistic quadrupole interaction. We have measured the magnetic moment of the second excited state of {sup 19}F using an external magnetic field. In the case of {sup 19}O, experiments of angular distributions and angular correlations of gamma -rays taking into account the possibility of perturbations, allow us to determine the spin and parities of the three first levels. (author) [French] Le present travail concerne l'etude de l'interaction des champs electromagnetiques et des moments nucleaires de noyaux emettant des rayonnements gamma. Nous decrivons des experiences de correlation angulaire differee dont l'interpretation met en coincidence le role joue par les interactions quadrupolaires statiques. Nous avons mesure le moment magnetique de {sup 19}F dans un etat excite en utilisant un champ magnetique exterieur a la source radioactive. Enfin, dans le cas de {sup 19}O, nous montrons l'utilite d'un examen des possibilites de perturbations dans l'interpretation des resultats fournis par des correlations ou des distributions angulaires. (auteur)

  12. Review of Development Status of Nuclear Superheat; Expose sur l'etat actuel des travaux concernant la surchauffe nucleaire; Obzor razrabotki voprosa o yadernykh peregrevatelyakh; Estudio de los progresos realizados en niateria de sobrecalentamiento nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Imhoff, D. H.; Pennington, R. T. [General Electric Company, San Jose, CA (United States)

    1963-10-15

    fuel irradiation performance, in-pile and out-of-pile uniform and localized corrosion evaluations, results from thermal superheat critical experiments, results from experimental heat-transfer testing and a brief appraisal of the economic incentives of the separate superheat reactor, integral superheat reactor, and mixed-spectrum superheat reactor design studies. (b) A brief description is given of the USAEC-Sponsored ESADA-VESR nuclear superheat fuel development programme. The development tasks, the initial core superheat fuel-element design, the range of experimental variables, and the expected results for the three-year fuel development programme are discussed. (author [French] Depuis 1959, la Societe General Electric s'occupe activement de mettre au point la surchauffe nucleaire dans les reacteurs ralentis a l'eau ordinaire. A cette epoque, le ''Superheat Advance Demonstration Experiment'' (SADE), finance par la societe, a permis d'obtenir, pour la premiere fois aux Etats-Unis, de la vapeur surchauffee par un dispositif nucleaire. Les auteurs du memoire font le point de la situation actuelle concernant la surchauffe nucleaire. Ils decrivent, dans une premiere partie, les trois principales installations de surchauffe nucleaire utilisees par la General Electric et, dans la seconde, les deux principaux programmes de recherches sur la surchauffe ainsi que les resultats les plus importants obtenus jusqu'ici dans ce domaine. 1. Principales installations pour les experiences de surchauffe: a) Breve description du SADE utilise dans le reacteur a eau bouillante de Vallecitos (VBWR), avec tableaux des conditions dans lesquelles se deroulent les experiences, et des elements combustibles irradies pendant la periode comprise entre mai 1959 et juin 1962; puis examen critique des resultats les plus importants ainsi obtenus. b) Breve description de l' ''Expanded Superheat Advance Demonstration Experiment'' (E-SADE) installe dans le reacteur de Vallecitos, avec tableaux des

  13. Order of the 24. of November 2009 approving the decision n. 2009-DC-0147 made on the 16. of July 2009 by the Nuclear Safety Authority (ASN) defining duties practice conditions of a person having abilities in radioprotection and external to the establishment to apply the R. 4456-4 article of the Labour Code

    International Nuclear Information System (INIS)

    2009-01-01

    This legal text approves a decision made by the ASN defining notably the content and formalization of the agreement between the employer and the person having abilities in radioprotection and who is external to the establishment. It also defines their reciprocal obligations. It indicates the groups of electrical equipment generating X rays and the groups of professional activities which are concerned by this order. It finally defines the requirements related the interventions of this person (frequency, mandatory interventions) with respect to the equipment groups

  14. Information note about the protection of nuclear facilities against aircraft crashes; Note d'information sur la protection des installations nucleaires contre les chutes d'avions

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    The protection of nuclear facilities against external risks (earthquakes, floods, fires etc..) is an aspect of safety taken into consideration by the French authority of nuclear safety (ASN). Concerning the aircraft crashes, the fundamental safety rules make three categories of aircraft: the small civil aircraft (weight < 5.7 t), the military aircraft, and the commercial aircraft (w > 5.7 t). Nuclear facilities are designed to resist against crashes of aircraft from the first category only, because the probability of the accidental crash of a big aircraft are extremely low. This document comprises an information note about the protection of nuclear facilities against aircraft crashes, a dossier about the safety of nuclear facilities with respect to external risks in general (natural disasters and aircraft crashes), and an article about the protection of nuclear power plants against aircraft crashes (design, safety measures, regulation, surveillance, experience feedback). (J.S.)

  15. High committee for transparency and information on nuclear safety: meeting of December 16, 2010; Haut Comite pour la Transparence et l'Information sur la Securite Nucleaire. Reunion du 16 decembre 2010

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    The discussion between members dealt with the following topics: the committee' program and implication with respect to the ACN approach (Aarhus Convention and Nuclear), the main orientations of the Transparency and Secret work group, the hearing of actors involved in a Tritium contamination incident in Valduc. These actors belonged to the CEA, to the 2M Process company, to the Nuclear safety authority or ASN, to the Institute for radiation protection and nuclear safety or IRSN, or to the Delegate to radiation protection and nuclear safety for installations of interest for the defence or DSND. Then the committee addressed the issue of old uranium mines and of places of use of uranium mining tailings. The committee members discuss the results of investigations performed around the Tricastin site (studies on cancers, on the presence of uranium in underground water sheets). Other topics are addressed: waste transportation to Germany, the French-British nuclear cooperation, the creation of a web site

  16. Obtaining of the UE’s Fabrication Autorisation and of Good Manufacturing Fabrication Practice

    Directory of Open Access Journals (Sweden)

    Rodica Morcov

    2009-12-01

    Full Text Available The harmonization of Romania’s legislation with the European Union’s one has as purpose the authentic equivalence archiving of the elaborated and applied measures on the Romania’s theritory with the ones legislated and applied in the other European Union state members.This is mandatory for the administrative procedure for the drow up of fabrication/import authorizations for the veterinary medicine products, in conformity with the European Commission published models and is assured in our country by the ANSVSA Presidents’ Order no. 57/2009, to the modification of the earlyer ANSVSA Presidents Order no. 187/2007 about the approval of the Veterinary Medicine Products Code, Sanitary Veterinary Norm, order which transponds the Commission Directive 2009/9/CE from 10th February 2009 and modiffying the Directive 2001/82/CE of the European Parliament and of the Council for the instituition of the Communitary code regarding the veterinary medicine products, published in the Official Journal of the European Union (JOUE no. L 44 from 14th February 2009, which implements in the national legislations the authorizations for fabrication/ import communitary format for the veterinary medicine products,published by the European Commission in the Reglementation of the Veterinary Medicine Products Norms, volume 4, published in the Official Monitor Part 1, no. 611/08.09.2009.

  17. The Enrico Fermi Atomic Power Plant; La centrais nucleaire Enrico Fermi; Atomnaya ehlektrostantsiya im Ehnriko Fermi.; La central nucleoelectrica Enrico Fermi

    Energy Technology Data Exchange (ETDEWEB)

    Hartwell, R. W. [Power Reactor Development Company, Detroit, MI (United States)

    1963-10-15

    sodium-water reaction took place in the No. 1 steam generator. The rupture disc, which was installed for such an eventuality, operated correctly. The cause and effect of this failure is currently being investigated. Completion of pre-operational testing. Anticipating the issuance of a low power licence, the final assembly and test programme is being completed in March. (author) [French] La construction de la centrale nucleaire Enrico Fermi, equipee d'un reacteur surgenerateur a neutrons rapides de 100 MWe, a ete virtuellement terminee en decembre 1961. Au cours des derniers 18 mois, on a minutieusement verifie les circuits et les parties constitutives. Ce programme de verifications avant la mise en service a ete tres utile pour verifier les plans et determiner les modifications a y apporter. Tous les problemes ont pu etre resolus. Voici la liste des principales modifications: Bouclier de graphite. En decembre 1960, on a rempli le circuit primaire de sodium liquide et on a procede a des essais tres pousses. Lorsqu'on a rouvert l'enceinte de protection primaire, apres les essais a 540{sup o}C, on a constate que la plus grande partie des blocs de graphite entourant le reacteur s'etait deterioree. Ces blocs, destines a supporter de hautes temperatures, etaient impregnes de bore; ils s'etaient dilates et avaient perdu leur resistance. Une analyse approfondie a montre que le liant du graphite avait cede. On a decide de remplacer tout le graphite, d'utiliser du carbure de bore a la place du bore, d'assujettir les blocs par des dispositifs mecaniques et de maintenir l'humidite a la valeur minimum. Modifications a l'interieur du caisson du reacteur. On a procede a des reparations et modifications pour supprimer la cause du collage des barreaux et les dommages qui en resultaient, et pour prevenir d'autres defaillances du mecanisme de manutention des cartouches. Pour ce faire, on a du retirer le mecanisme de manutention et vider le caisson contenant le sodium. Des specialistes

  18. Contribution to the study of nuclear fuel materials with a metallic uranium base; Contribution a l'etude des materiaux combustibles nucleaires a base d'uranium metallique

    Energy Technology Data Exchange (ETDEWEB)

    Englander, M. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1957-11-15

    In a power reactor destined to supply industrially recoverable thermal energy, the most economical source of heat still consists of natural metallic uranium. However, the nuclear fuel material, most often employed in the form of rods of 20 to 40 mm diameter, is subjected to a series of stresses which lead to irreversible distortions usually incompatible with the substructure of the reactor. As a result the fuel material must possess at the outset a certain number of qualities which must be determined. Investigations have therefore been carried out, first on the technological characters peculiar to each of the three allotropic phases of pure uranium metal, and on their interactions on the stabilisation of the material which consists of either cast uranium or uranium pile-treated in the {gamma} phase. (author) [French] Dans un reacteur de puissance destine a fournir de l'energie thermique industriellement recuperable, la source de chaleur la plus economique reste constituee par de l'uranium metallique naturel. Or, le materiau combustible nucleaire, employe le plus souvent sous forme de barreaux de 20 a 40 mm de diametre, se trouve soumis a un ensemble de contraintes qui provoque des deformations irreversibles, le plus souvent incompatibles avec l'infrastructure du reacteur. Par consequent, le materiau combustible doit presenter a l'origine un certain nombre de qualites qu'il est necessaire de determiner. Aussi a-t-on d'abord etudie les caracteres technologiques propres a chacune des trois phases allotropiques de l'uranium-metal pur et leurs interactions sur la stabilisation du materiau constitue soit par de l'uranium coule, soit par de l'uranium traite en pile en phase {gamma}. (auteur)

  19. Development of a software for a multi-processor system aimed at the on-line control of nuclear physics experiments; Developpement de logiciel pour un systeme multiprocesseur destine au controle en ligne d'experiences de physique nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Poggioli, Jean Renaud

    1984-03-02

    This research thesis reports the development of a software for an acquisition computer aimed at the on-line control of nuclear physics experiments. An original architecture, based on the assignment of a processor to each fundamental task, enables the implementation of a high performance system. In order to make the user free of programming constraints, the author developed a software for dynamic generation of acquisition and processing codes. These codes are created from a data base which is programmed by the user by using a language close to the physical reality. Procedures of interactive control of the experiment are thus simplified by displaying function menus on the operator terminal. The author evokes possible hardware improvements and possible extensions of the system [French] Cette these rend compte du developpement logiciel realise pour un calculateur d'acquisition destine au controle en ligne d'experiences de Physique Nucleaire. Une architecture originale, basee sur l'attribution d'un processeur a chacune des taches fondamentales permet de facon simple la mise en oeuvre d'un systeme a hautes performances. Le souci de liberer l'utilisateur des contraintes de programmation a conduit a l'elaboration d'un logiciel de generation dynamique des codes acquisition et traitement; ces derniers sont crees a partir d'une base de donnees que l'experimentateur programme a l'aide d'un langage approchant la realite physique. Les procedures de controle interactif de l'experience se trouvent simplifiees par l'affichage de menus de fonctions sur la console operateur. En conclusion sont evoquees les ameliorations materielles et les extensions possibles du systeme. (auteur)

  20. Development of a power-period calculation unit for nuclear reactor Control; Etude et realisation d'un ensemble de calcul puissance periode pour le controle d'un reacteur nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Martin, J [Commissariat a l' Energie Atomique, Centre d' Etudes Nucleaires de Saclay, 91 - Gif-sur-Yvette (France)

    1966-10-01

    The apparatus studied is a digital calculating assembly which makes it possible to prepare and to present numerically the period and power of a nuclear reactor during operation, from start-up to nominal power. The pulses from a fission chamber are analyzed continuously, using real time. A small number of elements is required because of the systematic use of a calculation technique comprising the determination of a base 2 logarithm by a linear approximation. The accuracy obtained for the period is of the order of 14%; the response time of the order of the calculated period value. An approximate value of the power (30%) is given at each calculation cycle together with the power thresholds required for the control. (author) [French] L'appareil etudie est un ensemble de calcul digital permettant d'elaborer et d'afficher numeriquement la periode et la puissance, d'un reacteur nucleaire lors de son fonctionnement depuis le demarrage jusqu'a la puissance nominale. Il traite en temps reel, de facon continue, les impulsions en provenance d'une chambre de fission. Grace a l'utilisation systematique d'une technique de calcul, la determination d'un logarithme a base 2 par approximation lineaire, un nombre reduit d'elements est utilise. La precision obtenue sur la periode est de l'ordre de 14 pour cent, le temps de reponse de l'ordre de la valeur de la periode calculee. Un ordre de grandeur de la puissance (30 pour cent) est donne a chaque cycle de calcul ainsi que des seuils de puissance necessaires au controle. (auteur)

  1. Regulation imposed to nuclear facility operators for the elaboration of 'waste studies' and 'waste statuses'; Reglementation imposee aux exploitants d'installations nucleaires pour l'elaboration ''des etudes dechets'' et ''des bilans dechets''

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-09-04

    This decision from the French authority of nuclear safety (ASN) aims at validating the new versions of the guidebook for the elaboration of 'waste studies' for nuclear facilities and of the specifications for the elaboration of 'waste statuses' for nuclear facilities. This paper includes two documents. The first one is a guidebook devoted to nuclear facility operators which fixes the rules of production of waste studies according to the articles 20 to 26 of the inter-ministry by-law from December 31, 1999 (waste zoning conditions and ASN's control modalities). The second document concerns the specifications for the establishment of annual waste statuses according to article 27 of the inter-ministry by-law from December 31, 1999 (rational management of nuclear wastes). (J.S.)

  2. Reports by the Parliamentary Office for scientific and technological assessments. Thursday, June 16, 2011. Transparency in nuclear safety; Comptes rendus de l' Office Parlementaire d'Evaluation des Choix Scientifiques et Technologiques. Jeudi 16 juin 2011. Transparence en matiere de surete nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-06-15

    In a first session dedicated to modalities of transparency in the field of nuclear safety, members of the French Parliament hear and discuss the interventions of representatives of the French nuclear safety authority (ASN), AREVA, EDF, the CEA, the French institute of radiation protection and nuclear safety (IRSN), of the High committee for transparency and information on nuclear safety (HCTISN). The second session addresses the improvement of transparency and comprised interventions by representatives of the OECD and of local commissions of information (ANCCLI)

  3. The Technical Training Programme for Nuclear Power Station Personnel; Programme de formation technique du personnel des centrales nucleaires; Programma tekhnicheskoj podgotovki personala yadernoj ehlektrostantsii; El programa de formacion tecnica del personal de una central nucleoelectrica

    Energy Technology Data Exchange (ETDEWEB)

    Howey, G. R. [Hydro-Electric Power Commission of Ontario, Toronto, Ontario (Canada)

    1963-10-15

    .), responsible for maintenance of all mechanical equipment; and (5) Service maintainers: responsible for a wide variety of less skilled tasks requiring lower qualifications. In addition to these general categories a few specialists are required, such as chemists and radiation protection officers. Organization of the NPD staff and training for future nuclear-power needs will be discussed. (author) [French] La centrale nucleaire de demonstration canadienne (NPD), creee par un organisme federal, l'Atomic Energy of Canada Limited, est exploitee par une compagnie provinciale de distribution d'electricite, la Hydro-Electric Power Commission of Ontario, qui pourvoit aussi aux besoins en personnel. Le recrutement et la formation du personnel de la centrale ont ete difficiles du fait que, recemment encore, la plupart des besoins en electricite de l'Ontario pouvaient etre satisfaits par les abondantes ressources hydro-electriques de cette province. La multiplication des centrales thermiques, depuis 1950, a cree une enorme demande de personnel. Pour faire face a cette situation, on a organise la formation de personnel pour les centrales nucleaires de la maniere suivante: a) un groupe initial d'ingenieurs a ete selectionne parmi des specialistes ayant une vaste experience des travaux dans le domaine nucleaire de l 'exploitation des centrales thermiques et de la production d'electricite; b) on a selectionne un autre groupe d'operateurs et d'agents des services d'entretien hautement qualifies; c) ces groupes ont recu une formation systematique comprenant l'exploitation de centrales nucleaires et de centrales thermiques a charbon, un enseignement theorique et pratique et des instructions donnees par les specialistes qui ont concu les plans de NPD ; d) un centre de formation nucleaire a ete cree et charge de la selection et de la formation du personnel supplementaire ainsi que de l 'organisation des examens officiels; il doit s'assurer, d'une maniere generale, de la competence du personnel

  4. High committee for nuclear safety transparency and information. September 23, 2008 meeting; Haut comite pour la transparence et l'information sur la securite nucleaire. Reunion du 23 septembre 2008

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-09-15

    The high committee for the nuclear safety transparency and information (HCTISN) is an information, consultation and debate authority devoted to the assessment of the risks linked with nuclear activities and to the analysis of their impact on public health, on the environment and on nuclear safety. Each year, the HCTISN organizes several ordinary meetings in order to analyze some specific topics of the moment. This meeting was organized around 6 main points: 1 - the terms of the High Committee operation and the internal rules for the meetings; 2 - the plutonium imports and transportation between Great Britain and France (contracts status, ship safety report, plutonium grade, return of plutonium-derived wastes): hearing of Areva, of the general direction of infrastructures, transports and sea (DGITM), of Greenpeace organisation, debate; 3 - the follow-up of the July 7, 2008 incident at the Socatri facility (Tricastin site (France)) where the overflow of a storage tank led to the spillage of a uraniferous solution on the ground: hearing of Areva (remedial action, re-start up of the facility, environmental monitoring, communication and transparency), hearing of the nuclear safety authority (ASN), of the institute of radiation protection and nuclear safety (IRSN), of the local commission of information (CIGEET), of the hygiene, safety and labour conditions committee (CHSCT) of Socatri company, of the direction of civil safety (DSC), debate about the information dissemination around this incident; 4 - Opinion of the High Committee about the plutonium transportation between Great Britain and France, and about the Socatri incident; 5 - referral to the High Committee of the radioecological follow up of all nuclear sites and of the quality of the information given to the public: ASN's reports about the radioecological follow-up of surface and ground waters and of the ancient radioactive waste storage sites, ASND's answer (Nuclear safety authority of defense), IRSN

  5. High committee for nuclear safety transparency and information. November 20, 2009 meeting of the High Committee; Haut comite pour la transparence et l'information sur la securite nucleaire. Reunion du Haut comite, 20 novembre 2009

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-11-15

    The high committee for the nuclear safety transparency and information (HCTISN) is an information, consultation and debate authority devoted to the assessment of the risks linked with nuclear activities and to the analysis of their impact on public health, on the environment and on nuclear safety. Each year, the HCTISN organizes several ordinary meetings in order to analyze some specific topics of the moment, and, depending on the events, some extraordinary meetings. This document is the proceedings of an extraordinary meeting about the information and transparency in relation with the management of nuclear materials and wastes at all stages of the fuel cycle. The reason of this meeting is a request from the French Minister of ecology, energy, sustainable development and sea (MEEDDM) after the broadcast of a TV documentary entitled 'wastes: the nuclear industry nightmare' and the publication of a press article affirming that 'our nuclear wastes are hidden in Siberia'. The Minister expressed his wish to have the question of the international trade of nuclear materials examined by the HCTISN. The document is organized as follows: a first part presents the hearings of the general direction of energy and climate (DGEC), of the nuclear safety authority (ASN), of EdF, of Areva, of the CEA, of the senior official for the defense and security of the MEEDDM, of Rosatom company and of Greenpeace organisation. A second part examines the incident which took place in October 2009 at the plutonium technology workshop (ATPu) of Cadarache, where about 22 to 39 kg of plutonium powder were discovered in the gloveboxes of this facility, decommissioned in 2005 and undergoing dismantlement today. This part presents the hearings of the CEA, of AREVA, of the Institute of radiation protection and nuclear safety (IRSN), of the ASN, of the hygiene, safety and labour conditions committee (CHSCT) of Areva and CEA, and of the local information commission (CLI) of Cadarache

  6. Atomic Transport Problems of Interest in Nuclear Systems; Problemes de Transport Atomique Presentant un Interet dans les Systemes Nucleaires; Problemy perenosa atomov, predstavlyayushchie interes v yadernykh sistemakh; Problemas de Transporte Atomico de Interes para la Ingenieria Nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Lundy, T. S.; Winslow, F. R. [Oak Ridge National Laboratory, TN (United States)

    1966-02-15

    ) [French] Les auteurs discutent plusieurs problemes qui surgissent lorsqu'on veut appliquer les constantes fondamentales de diffusion a des systemes presentant un interet pratique, notamment a ceux que l'on rencontre dans le genie nucleaire. Ces problemes comprennent des experiences de diffusion isotherme, la diffusion sous gradient thermique et les effets de rayonnements sur les processus de diffusion. La plupart des donnees dignes de foi sur la diffusion dans les solides ont ete obtenues a partir de cas dans lesquels il n'y avait essentiellement pas de gradient de concentration des especes diffusantes. Toutefois, dans les systemes qui presentent un interet pour les specialistes du genie nucleaire, il y a presque invariablement des gradients de concentration. C'est pourquoi il faut avoir une connaissance pratique de la relation entre les coefficients d'autodiffusion et de diffusion chimique pour pouvoir determiner les coefficients applicables dans chaque cas d'espece. En outre, il faut egalement connaitre les coefficients d'activite thermodynamique en fonction de la composition. Recemment, il a ete clairement demontre qu'il est dangereux d'utiliser aveuglement une expression d'Arrhenius pour decrire les variations de la diffusion selon la temperature, car cela peut entrainer des erreurs considerables dans le calcul theorique des coefficients de diffusion. Les auteurs discutent les consequences qui en decoulent, particulierement pour les systemes cubiques centres refractaires. Ils ont etudie, tant theoriquement qu'experimentalement, l'effet d'un gradient thermique sur la distribution des impuretes de substitution dans un metal. Ces travaux ont permis de mieux apprecier l'importance de cet effet dans des systemes presentant un interet du point de vue nucleaire. L'accroissement de la diffusion par les champs de rayonnements demeure toujours un probleme d'un interet reel. Les auteurs ont fait les premieres mesures directes de l'effet du bombardement par des particules rapides

  7. Case Study in Internal Audit of Nuclear Material; Etude d'un Systeme de Verification Comptable Interne des Matieres Nucleaires; Izuchenie primera organizatsii vnutrennego ucheta yadernykh materialov na predpriyatii; Estudio de la Fiscalizacion Interna de los Materiales Nucleares

    Energy Technology Data Exchange (ETDEWEB)

    Kops, S. [United States Atomic Energy Commission, Argonne, IL (United States)

    1966-02-15

    sont generalement les principaux facteurs a considerer lorsque l'on veut determiner s'il y a lieu d'etablir un systeme classique de verification comptable interne. L'auteur analyse les besoins et les caracteristiques d'un systeme de verification comptable interne dans le cas particulier d'une organisation qui manipule des matieres brutes ou des produits fissiles speciaux (matieres nucleaires), en les confrontant a ceux d'un systeme de verification classique. Il montre comment, etant donne le prix eleve et la valeur strategique des matieres, il est necessaire d'etablir un systeme special de verification comptable. Le memoire etudie en detail l'organisation du systeme de verification comptable interne dans une installation produisant des matieres nucleaires; il indique notamment comment fixer la date des controles et comment proceder a la verification des livres et inventaires. Il indique egalement la competence et les qualifications professionnelles que doit avoir le personnel charge de la verification comptable, ainsi que les considerations d'ordre statistique a appliquer pour determiner les donnees qui devront faire l'objet d'une verification. Le memoire decrit de facon detaillee la maniere dont ces dispositions sont appliquees dans la pratique de la verification comptable interne. Il indique les modifications qui peuvent etre apportees aux normes etablies ainsi que les differentes manieres d'envisager le probleme de la verification des comptes et montre que, s'il est possible dans le cas d'autres fabrications de proceder simplement a une verification comptable des stocks, il est necessaire dans l'industrie nucleaire de proceder effectivement a l'inventaire materiel du stock. Le memoire presente les divers moyens utilises pour communiquer les resultats de la verification interne. La presentation du rapport comptable et sa teneur sont determinees en fonction des besoins des differents services. Le memoire indique les diverses manieres dont le rapport comptable peut

  8. Study and installation of concrete shielding in the civil engineering of nuclear construction (1960); Etude et mise en place des betons de protection dans le genie civil des ouvrages nucleaires (1960)

    Energy Technology Data Exchange (ETDEWEB)

    Dubois, F [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1960-07-01

    sont decrites telles qu'elles ont ete realisees au Centre d'Etudes Nucleaires de Saclay. Des specifications sont donnees pour les betons de barytine et pour la fabrication des blocs de protection du synchrotron a protons 'Saturne'. (auteur)

  9. Study and installation of concrete shielding in the civil engineering of nuclear construction (1960); Etude et mise en place des betons de protection dans le genie civil des ouvrages nucleaires (1960)

    Energy Technology Data Exchange (ETDEWEB)

    Dubois, F. [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1960-07-01

    etudes, deux applications pratiques sont decrites telles qu'elles ont ete realisees au Centre d'Etudes Nucleaires de Saclay. Des specifications sont donnees pour les betons de barytine et pour la fabrication des blocs de protection du synchrotron a protons 'Saturne'. (auteur)

  10. The Management of Nuclear Materials in a Research Establishment; Gestion des Matieres Nucleaires dans un Centre de Recherche; Uchet yadernykh materialov v nauchno-issledovatel'skom uchrezhdenii; Administracion de Sustancias Nucleares en un Centro de Investigaciones

    Energy Technology Data Exchange (ETDEWEB)

    Wright, W. J.; Hocking, D. R. [Australian Atomic Energy Commission Research Establishment, Lucas Heights, NSW (Australia)

    1966-02-15

    The functions of a nuclear materials management scheme are reviewed in relation to the activities of research establishments. Since these activities are normally non-repetitive, there is little opportunity to establish statistical quality and quantity control. The risks of an error in the material accounts must therefore be established from relatively few analytical measurements and the implications of this are discussed. Similar arguments are applied to illustrate the difficulties of quality control on suppliers when a large variety of materials are being purchased in small quantities. (author) [French] Les auteurs examinent le role d'un systeme de gestion des matieres nucleaires applique aux activites des centres de recherche. Comme ces activites ne sont normalement pas appelees a se repeter, il n'est guere possible d'organiser un controle statistique quantitatif et qualitatif. Il faut donc determiner les possibilites d'erreurs dans la comptabilite matieres en s'appuyant sur un nombre relativement restreint de mesures analytiques et les auteurs examinent les conclusions a tirer de cette situation. Ils recourent a une argumentation analogue pour illustrer les difficultes inherentes au controle de la qualite des matieres livrees par les fournisseurs lorsqu'il doit porter sur une grande diversite de matieres en petites quantites. (author) [Spanish] Los autores examinan el funcionamiento de un sistema de administracion de materiales nucleares en relacion con las actividades de los centros de investigaciones. Como estas actividades son por lo comun muy diversas, hay pocas oportunidades de establecer un control estadistico de la calidad y la cantidad. Por ello es necesario determinar los riesgos de error en la contabilidad de los materiales partiendo de un numero relativamente reducido de mediciones analiticas; en la memoria se examinan las consecuencias de este hecho. Los autores aplican razonamientos analogos para poner de manifiesto las dificultades con que, en el

  11. Communication Received from Certain Member States Regarding Guidelines for Transfers of Nuclear-related Dual-use Equipment, Material, Software and Related Technology; Communication recue de certains Etats Membres concernant les directives applicables aux transferts d'equipements, de matieres et de logiciels a double usage dans le domaine nucleaire, ainsi que de technologies connexes

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-09-09

    The Agency has received a Note Verbale from the Permanent Mission of Hungary, dated 14 June 2010, in which it requests that the Agency circulate to all Member States a letter of 7 May 2010 from the Chairman of the Nuclear Suppliers Group, Ambassador Ms. Gyorgyi Martin Zanathy, to the Director General, on behalf of the Governments of Argentina, Australia, Austria, Belarus, Belgium, Brazil, Bulgaria, Canada, China, Croatia, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Japan, Kazakhstan, Republic of Korea, Latvia, Lithuania, Luxemburg, Malta, Netherlands, New Zealand, Norway, Poland, Portugal, Romania, Russian Federation, Slovakia, Slovenia, South Africa, Spain, Sweden, Switzerland, Turkey, Ukraine, the United Kingdom of Great Britain and Northern Ireland and the United States of America,1 providing further information on those Governments' Guidelines for Nuclear Transfers [French] L'Agence a recu une note verbale de la mission permanente de la Hongrie, en date du 14 juin 010, lui demandant de communiquer a tous les Etats Membres une lettre du 7 mai 2010 du president du Groupe des fournisseurs nucleaires, l'ambassadeur Gyorgyi Martin Zanathy, adressee au Directeur general au nom des gouvernements des Etats suivants : Afrique du Sud, Allemagne, Argentine, Australie, Autriche, Belarus, Belgique, Bresil, Bulgarie, Canada, Chine, Croatie, Chypre, Danemark, Espagne, Estonie, Etats-Unis d'Amerique, Federation de Russie, Finlande, France, Grece, Hongrie, Irlande, Islande, Italie, Japon, Kazakhstan, Lettonie, Lituanie, Luxembourg, Malte, Norvege, Nouvelle-Zelande, Pays-Bas, Pologne, Portugal, Republique de Coree, Republique tcheque, Roumanie, Royaume-Uni de Grande-Bretagne et d'Irlande du Nord, Slovaquie, Slovenie, Suede, Suisse, Turquie et Ukraine1. Cette lettre apporte des informations supplementaires sur les Directives de ces gouvernements applicables aux transferts nucleaires.

  12. Communication Received from the Permanent Mission of Brazil regarding Certain Member States' Guidelines for the Export of Nuclear Material, Equipment and Technology; Communication recue de la mission permanente du Bresil concernant les Directives de certains Etats Membres applicables a l'exportation de matieres, d'equipements et de technologie nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-12-03

    The Agency has received a Note Verbale from the Permanent Mission of Brazil, dated 22 March 2007, in which it requests that the Agency circulate to all Member States a letter of 12 December 2006 from the Chairman of the Nuclear Suppliers Group, Ambassador Jose Artur Denot Medeiros, to the Director General, on behalf of the Governments of Argentina, Australia, Austria, Belarus, Belgium, Brazil, Bulgaria, Canada, China, Croatia, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Japan, Kazakhstan, Republic of Korea, Latvia, Lithuania, Luxemburg, Malta, Netherlands, New Zealand, Norway, Poland, Portugal, Romania, Russian Federation, Slovakia, Slovenia, South Africa, Spain, Sweden, Switzerland, Turkey, Ukraine, the United Kingdom of Great Britain and Northern Ireland and the United States of America, providing further information on those Governments' Guidelines for Nuclear Transfers [French] L'Agence a recu une note verbale de la mission permanente du Bresil, en date du 22 mars 2007, lui demandant de diffuser a tous les Etats Membres une lettre du 12 decembre 2006 du president du Groupe des fournisseurs nucleaires, l'ambassadeur Artur Denot Medeiros, adressee au Directeur general au nom des gouvernements des Etats suivants : Afrique du Sud, Allemagne, Argentine, Australie, Autriche, Belarus, Belgique, Bresil, Bulgarie, Canada, Chine, Chypre, Croatie, Danemark, Espagne, Estonie, Etats-Unis d'Amerique, Federation de Russie, Finlande, France, Grece, Hongrie, Irlande, Italie, Japon, Kazakhstan, Lettonie, Lituanie, Luxembourg, Malte, Norvege, Nouvelle-Zelande, Pays-Bas, Pologne, Portugal, Republique de Coree, Republique tcheque, Roumanie, Royaume-Uni de Grande-Bretagne et d'Irlande du Nord, Slovaquie, Slovenie, Suede, Suisse, Turquie et Ukraine. Cette lettre apporte des informations supplementaires sur les Directives de ces gouvernements applicables aux transferts nucleaires.

  13. Communication Received from the Permanent Mission of the Netherlands regarding Certain Member States' Guidelines for the Export of Nuclear Material, Equipment and Technology; Communication recue de la mission permanente des Pays-Bas concernant les Directives de certains Etats Membres applicables a l'exportation de matieres, d'equipements et de technologie nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-09-05

    The Agency has received a Note Verbale from the Permanent Mission of the Kingdom of the Netherlands, dated 12 July 2011, in which it requests that the Agency circulate to all Member States a letter of 12 July 2011 from the Chairman of the Nuclear Suppliers Group, Ambassador Piet de Klerk, to the Director General, on behalf of the Governments of Argentina, Australia, Austria, Belarus, Belgium, Brazil, Bulgaria, Canada, China, Croatia, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Japan, Kazakhstan, Republic of Korea, Latvia, Lithuania, Luxembourg, Malta, the Netherlands, New Zealand, Norway, Poland, Portugal, Romania, Russian Federation, Slovakia, Slovenia, South Africa, Spain, Sweden, Switzerland, Turkey, Ukraine, the United Kingdom of Great Britain and Northern Ireland and the United States of America, providing further information on those Governments' Guidelines for Nuclear Transfers [French] L'Agence a recu une note verbale de la mission permanente du Royaume des Pays-Bas, en date du 12 juillet 2011, lui demandant de communiquer a tous les Etats Membres une lettre du 12 juillet 2011 du president du Groupe des fournisseurs nucleaires, l'ambassadeur Piet de Klerk, adressee au Directeur general au nom des gouvernements des Etats suivants : Afrique du Sud, Allemagne, Argentine, Australie, Autriche, Belarus, Belgique, Bresil, Bulgarie, Canada, Chine, Croatie, Chypre, Danemark, Espagne, Estonie, Etats-Unis d'Amerique, Federation de Russie, Finlande, France, Grece, Hongrie, Irlande, Islande, Italie, Japon, Kazakhstan, Lettonie, Lituanie, Luxembourg, Malte, Norvege, Nouvelle-Zelande, Pays-Bas, Pologne, Portugal, Republique de Coree, Republique tcheque, Roumanie, Royaume-Uni de Grande-Bretagne et d'Irlande du Nord, Slovaquie, Slovenie, Suede, Suisse, Turquie et Ukraineb. Cette lettre apporte des informations supplementaires sur les Directives de ces gouvernements applicables aux transferts nucleaires.

  14. Order of the 29. of January 2010 approving the decision n. 2009-DC-0148 made on the 16. of July 2009 by the Nuclear Safety Authority (ASN) related to the detailed content of information which must be attached to declarations of nuclear activities being applied by paragraphs 1 and 3 of the R. 1333-19 of the Public Health Code; Arrete du 29 janvier 2010 portant homologation de la decision no 2009-DC-0148 de l'Autorite de surete nucleaire du 16 juillet 2009 relative au contenu detaille des informations qui doivent etre jointes aux declarations des activites nucleaires visees aux 1o et 3o de l'article R. 1333-19 du code de la sante publique

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    This legal text defines the detailed content of information which must be attached to declarations required on the account of an article of the French Public Health Code. This information comprises a specific form and a file, the content of which is specified in appendix and may depend on whether it concerns a first declaration or a new declaration after modification. Another appendix defines the documents and information which must be kept at the disposal of authorities and organisations in charge of radioprotection controls and of nuclear safety

  15. Reports by the Parliamentary Office for scientific and technological assessment. Wednesday, March 16, 2011. Nuclear crisis in Japan - Round table; Comptes rendus de l' Office Parlementaire d'Evaluation des Choix Scientifiques et Technologiques. Mercredi 16 mars 2011. Crise nucleaire au Japon - Table ronde

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-03-15

    A round table brought together members of the French national Assembly and Senate, the French ministers of ecology and of industry, the chairmen of the Nuclear Safety Authority (ASN), of the OECD agency for nuclear energy, of AREVA, of EDF and of the High Committee for transparency and information on nuclear safety, and representatives of the IRSN and of the CEA. Three main topics have been addressed: the present technical configuration of the Fukushima site, the situation at the vicinity of the power station and on the whole Japanese territory, and the possible evolution scenarios

  16. Notes on the Start-Up of the Latina Power Station; Notes concernant le demarrage de la centrale nucleaire de Latina; Zapusk ehlektrostantsii Latina; Notas sobre la puesta en marcha de la central electrica de Latina

    Energy Technology Data Exchange (ETDEWEB)

    Calabria, G.; Gualtieri, G. [AGIP Nucleare, Milano (Italy)

    1963-10-15

    Information is given on the start-up of the first Italian nuclear power plant, the Latin Power Station, designed for an electrical output of 200 MW, incorporating a natural uranium-gas-graphite reactor. After a brief description of the main characteristics of the station, details are given on die performance of the final tests of the plant, on the fuel loading and on the sequence of commissioning operations, measurements and controls subsequent to the criticality attained. The operations for the start-up and connection of the station to the electrical network are treated. The organization problems relevant to the station operation including personnel preparation and qualification, safety measures, are also illustrated. (author) [French] Le memoire donne des renseignements sur le demarrage de la premiere centrale nucleaire italienne, la centrale de Latina, dont la puissance electrique est de 200 MW et qui fonctionne avec un reacteur du type uranium naturel-gaz-graphite. Apres une breve description des caracteristiques essentielles de la centrale, des explications detaillees sont donnees sur les resultats des derniers essais auxquels elle a ete soumise, sur le chargement du combustible et sur la serie des operations de mise en service, des mesures et des verifications auxquelles il a ete procede lorsque l'etat critique a ete atteint. Les operations de demarrage et de raccordement de la centrale au reseau electrique sont etudiees dans le memoire, ainsi que les problemes d'organisation que pose l 'exploitation de la centrale, notamment en ce qui concerne la formation du personnel et les mesures de securite. (author) [Spanish] Se comunican datos sobre la puesta en marcha de la primera central nucleoelectrica italiana, en Latina, proyectada para desarrollar una potencia de 200 MW (e), que se basa en un reactor de uranio natural moderado por grafito u refrigerado por gas. Despues de describir brevemente las caracteristicas de la central, se dan detalles sobre el

  17. Criteria for Special Nuclear Materials Inventory and Control Procedures; Criteres a Suivre Pour Proceder a l'Inventaire des Matieres Nucleaires Speciales et aux Mesures de Controle; Kriterii dlya inventarizatsii spetsial'nykh yadernykh materialov i metody ucheta; Criterios a Que Deben Ajustarse los Procedimientos de Inventario y Control de los Materiales Nucleares Especiales

    Energy Technology Data Exchange (ETDEWEB)

    Kinderman, E. M.; Tarrice, R. R. [Stanford Research Institute, Menlo Park, CA (United States)

    1966-02-15

    and the total inventory of these special nuclear materials. A matrix of solutions to the management and inventory control of special nuclear materials will be presented. The multiplicity and relative effectiveness of varied techniques at key stages of the materials supply, utilization and recovery are assessed. (author) [French] L'un des plus importants problemes qui, dans le domaine nucleaire et notamment dans l'exploitation commerciale de l'energie d'origine nucleaire, se posera aux societes d'investissement, aux directeursetaux exploitants est celui du controle efficace de l'inventaire des matieres nucleaires dont la valeur depassera, d'ici 1980, 5 milliards de dollars des Etats-Unis. Comparativement a la plupart des matieres utilisees commercialement, les matieres nucleaires speciales sont couteuses; aux Etats-Unis par exemple, l'uranium enrichi a 90%, l'uranium enrichi a 3% sous forme d'hexa- fluorure et l'eau lourde coutent respectivement 10808 dollars, 254 dollars et 61,60 dollars le kilo. En outre, ces matieres sont frequemment soumises, pour des raisons de protection sanitaire et de securite, a des controles gouvernementaux speciaux sans rapport direct avec leur valeur monetaire. En depit de leur prix eleve, ces matieres sont destinees a etre utilisees en grandes quantites; par exemple, on utilisera de 50 a 75 t de combustible enrichi a 3{sup o}{r_brace}o dans un reacteur de 500 MW modere a l'eau ordinaire et 200 a 300 reacteurs de cette puissance fonctionneront vraisemblablement dans le monde en 1980. L'experience acquise a permis la mise au point et l'application de methodes speciales pour le controle commercial de grandes quantites de matieres de faible valeur comme le charbon ou le minerai de fer ou de petites quantites de matieres de grande valeur comme les metaux precieux. Tout en ayant des prix comparables a ces derniers, les matieres nucleaires speciales sont de nature differente et seront utilisees en quantites beaucoup plus importantes que les

  18. Reports by the Parliamentary Office for scientific and technological assessments. Tuesday, May 31, 2011. Hearing opened to the press on the organization of nuclear safety; Comptes rendus de l' Office Parlementaire d'Evaluation des Choix Scientifiques et Technologiques. Mardi 31 mai 2011. Audition, ouverte a la presse, sur l'organisation de la securite nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-05-15

    Members of the French Parliament, and representatives of the French nuclear safety authority (ASN), of the European Nuclear Safety Regulators Group (ENSREG), of the IAEA, of the World Association of Nuclear Operators (WANO), of the French institute for radiation protection and nuclear safety (IRSN) first address the international dimension of nuclear safety control. They describe, comment and discuss the situation of the Fukushima nuclear plant, the impact of this accident on France (cooperation with Japan, atmospheric measurement in France), the different national approaches to nuclear safety, the specifications for the audit of the French nuclear power plants and the security assessments foreseen for the European nuclear stock, the issue of international standard elaboration, the activity of the WANO in the field of international cooperation. In a second part, members of Parliament and representatives of the ASN, the IRSN, EDF, and AREVA and of the French committee of certification of companies for the training and monitoring of personnel working under ionizing radiation (CEFRI) describe, comment and discuss the nuclear safety modalities in France

  19. Order of the 29. of January 2010 approving the decision n. 2009-DC-0146 made on the 16. of July 2010 by the Nuclear Safety Authority (ASN), modified by the decision n. 2009-DC-0162 of the 20. of October 2009, defining the list electric equipment generating X rays which are hold or used for purposes of biomedical research or medical, dental, forensics or veterinary diagnosis and submitted to a declaration regime on the account of the first paragraph of the article R. 1333-19 of the Public Health code and abrogating the 23 April 1969 order related to equipment and installations using ionizing radiations on medical purposes

    International Nuclear Information System (INIS)

    2010-01-01

    This legal document indicates the list of equipment which must now be declared to the ASN (the French Nuclear Safety Authority), specifies that any use of these equipment in conditions other than normal requires an authorization on the account of an article of the Public Health Code. A list of equipment is given which are used in medical and forensics radio-diagnosis, in biomedical research, in dental and veterinary radio-diagnosis

  20. Order of the 29. of January 2010 approving the decision n. 2009-DC-0146 made on the 16. of July 2010 by the Nuclear Safety Authority (ASN), modified by the decision n. 2009-DC-0162 of the 20. of October 2009, defining the list electric equipment generating X rays which are hold or used for purposes of biomedical research or medical, dental, forensics or veterinary diagnosis and submitted to a declaration regime on the account of the first paragraph of the article R. 1333-19 of the Public Health code and abrogating the 23 April 1969 order related to equipment and installations using ionizing radiations on medical purposes

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    This legal document indicates the list of equipment which must now be declared to the ASN (the French Nuclear Safety Authority), specifies that any use of these equipment in conditions other than normal requires an authorization on the account of an article of the Public Health Code. A list of equipment is given which are used in medical and forensics radio-diagnosis, in biomedical research, in dental and veterinary radio-diagnosis

  1. Preparation and study of the properties of lead telluride and cadmium telluride diodes for use in nuclear spectrometry; Preparation et etude des proprietes de diodes au tellurure de plomb et au tellurure de cadmium en vue d'une utilisation en spectrometrie nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Lancon, R [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1969-07-01

    This work studies the possibility of using high atomic number compound semiconductors, like lead telluride and cadmium telluride as to realize nuclear radiation detectors, specially in gamma ray spectrometry because of their high absorption coefficient. The problems related to the preparation of binary compounds are exposed. Experiments on PbTe show the influence of the conditions of preparation on the electrical properties of the semiconductor which are greatly dependent on the stoichiometry of the compound. PbTe surface-barrier diodes were realized and have been used to study the surface properties of this semiconductor. These diodes cannot detect nuclear radiations because of the too weak resistivity of our material. Different types of devices made of Cd Te have been studied. One of these diodes has been used as an alpha particle detector. We explain the relative poor performances of that detector by the presence of lattice defects in Cd Te where charge carriers may recombine themselves. By analysing the properties of gold diffused Cd Te diodes we identified this defect, the cadmium vacancy, the presence of which is due to the deviation from stoichiometry during the preparation of the material. (author) [French] Ce travail etudie la possibilite d'utiliser des semiconducteurs composes d'elements a numero atomique eleve, tels que le tellurure de plomb et le tellurure de cadmium pour la realisation de detecteurs de rayonnements nucleaires, grace notamment a la section efficace de capture elevee qu'ils presentent vis-a-vis des rayons gamma. On souligne les problemes relatifs a la preparation des composes binaires. Les experiences realisees sur PbTe mettent en evidence l'influence des conditions de preparation sur les proprietes electriques du semiconducteur qui dependent fortement de la stoechiometrie du compose. Nous avons realise des diodes au PbTe a barriere de surface qui ont permis de preciser les proprietes de surface de ce semiconducteur. La trop faible

  2. Behaviour of semiconductor nuclear-particle detectors; Comportement des semi-conducteurs comme detecteurs de particules nucleaires; Povedenie detektorov yadernykh chastits na poluprovodnikakh; Propiedades de los detectores de particulas nucleares a base de semiconductores

    Energy Technology Data Exchange (ETDEWEB)

    Walter, F J; Dabbs, J W.T.; Roberts, L D [Oak Ridge National Laboratory, Oak Ridge, TN (United States)

    1962-04-15

    . Matched expansion-coefficient fabrication techniques which have been successfully used to make detectors up to 8 cm{sup 2} in active area are also described. (author) [French] Les auteurs ont fait des etudes theoriques et experimentales sur le comportement des semi-conducteurs comme detecteurs de particules nucleaires a des temperatures allant de 0,2{sup o} K a 300{sup o} K. Ils presentent un modele theorique simple du comportement du detecteur qui correspond au comportement observe pour toute une gamme de valeurs des parametres. Ils examinent quelle est l'importance de la purete du semi-conducteur et de la tension de polarisation en ce qui concerne l'amplitude de l'impulsion, le temps de montee de l'impulsion et la surface du detecteur. Des etudes empiriques sur le bruit et la resolution en energie montrent que, pour des particules alpha, les plus petites largeurs de crete observees sont tres nettement plus importantes que les largeurs que l'on avait prevues en tenant compte du bruit d'origine electrique provenant du detecteur et de l'amplificateur. A 77{sup o}K, on a releve pour un detecteur a barriere de surface au silicium, d'une surface de 40 mm{sup 2}, des intensites de bruit equivalant a {<=} 3 keV (largeur totale a mi-hauteur du maximum). Les semi-conducteurs presentent un a l'egard des fragments de fission. On a tout lieu de penser que ce defaut n'est pas du a une . Si des champs electriques insuffisants pour assurer une complete sont la cause de ce defaut, le gradient de champ necessaire (a la surface) est superieur a 3 {center_dot} 10{sup 4} V/cm dans le cas de fragments de fission contre 2 {center_dot} 10{sup 3} V/cm dans le cas de particules alpha de Ge et de Si. Des etudes detaillees sur le temps de montee des impulsions au niveau de l'amplificateur ont montre que pour des substances de grande resistivite le temps de relaxation dielectrique et la resistance propres aux substances de base non appauvries peuvent

  3. New Frontiers for Non-Destructive Testing in the Nuclear Age; Perspectives des Essais Non Destructifs a l'Ere Nucleaire; ''Novye rubezhi'' nedestruktivnykh ispytanij v yadernyj vek; Nuevas Posibilidades de los Ensayos No Destructivos en la Era Nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Ballard, D. W. [Sandia Laboratory Albuquerque, NM (United States)

    1965-10-15

    suitable for remote television displays and recording. Test parameters, display capabilities, and continuous monitoring systems are discussed. These possibilities have. already been demonstrated in laboratory testing and their use must be extended to production testing if a new level of reliability of components in the nuclear industry is to be achieved. (author) [French] On peut attribuer en grande partie l'extraordinaire developpement des essais non destructifs depuis la deuxieme guerre mondiale aux specifications extremement strictes imposees aux materiaux et produits de l'industrie nucleaire. La complexite des installations et de leurs elements et les incidences financieres des arrets de fonctionnement ont atteint des proportions telles qu'il est imperieux de mettre au point des methodes plus efficaces d'essais non destructifs et de les appliquer tout au long de la duree de vie des produits, depuis leur mise en fabrication jusqu'a leur declassement. En meme temps que, pour tenter de satisfaire aux imperatifs techniques de perfection, on developpe considerablement les possibilites offertes par des methodes d'essais confirmees, comme la radiographie, les ultrasons et l'electromagnetisme, on met au point de nouveaux principes d'essais destines expressement au controle des performances statiques et dynamiques. Le memoire porte sur ces methodes particulierement rapides et sensibles qui ouvrent vraiment de nouvelles perspectives aux essais non destructifs. Au nombre des methodes d'essais les plus recentes discutees dans le memoire figure le controle par les infra- rouges de l'integrite des soudures. Le controle cineradiographique des structures au cours des essais de vibration, pour etudier leur comportement dynamique, est egalement traite. La detection des fuites est extremement importante pour assurer la qualite des elements combustibles. Le memoire decrit une methode de controle des elements combustibles sous gaine, qui est fondee sur l'utilisation d'un gaz radioactif et

  4. Nuclear wastes management; Gestion des dechets nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    This document is the proceedings of the debate that took place at the French Senate on April 13, 2005 about the long-term French policy of radioactive wastes management. The different points tackled during the debate concern: the 3 axes of research of the 1991 law, the public acceptance about the implementation of repositories, the regional economic impact, the cost and financing, the lack of experience feedback, the reversibility or irreversibility of the storage, the share of nuclear energy in the sustainable development policy, the European Pressurized Reactor (EPR) project, the privatization of Electricite de France (EdF) etc. (J.S.)

  5. The Manhattan project; Nucleaire - Le Projet Manhattan

    Energy Technology Data Exchange (ETDEWEB)

    Alexieff, A.

    2010-07-15

    The author reports the history of the Manhattan project which was launched in 1942 with the objective of building an A bomb at any price and as soon as possible. This lead to the fabrication of two types of bomb, one using uranium in gun mode, and the other using plutonium in implosion mode. The author recalls the creation of different scientific and nuclear institutions, the development of several installations (Los Alamos, Hanford, Oak Ridge). He outlines the project secrecy (President Truman did not know anything about it when he became president), and recalls the final tests, the bombing of Hiroshima and Nagasaki, and the last moment of the Manhattan Project after the end of the war. In conclusion, he notices that this nuclear era allowed a direct confrontation to be avoided despite the several crises which occurred during about two decades after the war

  6. The nuclear refugees; Les refugies du nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Linton, M.

    2011-06-15

    The authors propose a report on the various situations of people who had to be evacuated after the Fukushima accident. Along with examples of people who left their homes with taking with them a single object, the authors describe and comment how this evacuation occurred, the problems faced by the authorities for refugee reception and accommodation. This evacuation has been either organised or spontaneous. Hospitals had to be evacuated as well. Then, local authorities faced food shortage. Some animals have been saved, other starved to death. Dead animals are covered with lime. Dead bodies are decontaminated before being given back to families. Tests are regularly performed to assess people contamination. A second article discussed the bad news concerning the different Fukushima reactors with their melted cores. The geophysical aspects of the earthquake are evoked in a last article

  7. Nuclear reactor (1960); Reacteurs nucleaires (1960)

    Energy Technology Data Exchange (ETDEWEB)

    Maillard, M L [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires; Leo, M B [Electricite de France (EDF), 75 - Paris (France)

    1960-07-01

    The first French plutonium-making reactors G1, G2 and G3 built at Marcoule research center are linked to a power plant. The G1 electrical output does not offset the energy needed for operating this reactor. On the contrary, reactors G2 and G3 will each generate a net power of 25 to 30 MW, which will go into the EDF grid. This power is relatively small, but the information obtained from operation is great and will be helpful for starting up the power reactor EDF1, EDF2 and EDF3. The paper describes how, previous to any starting-up operation, the tests performed, especially those concerned with the power plant and the pressure vessel, have helped to bring the commissioning date closer. (author) [French] Les premiers reacteurs industriels plutonigenes francais G1 - G2 - G3 du Centre de Marcoule comportent une installation de recuperation d'energie. La production d'electricite de G1 ne compense pas l'energie depensee par ailleurs pour le fonctionnement de l'ensemble, par contre, G2 et G3 doivent fournir chacun une puissance de 25 a 30 MW au reseau national d'Electricite de France. Cette puissance est modeste, mais l'experience acquise grace a ces reacteurs est tres grande et c'est grace a elle qu'il nous sera possible de mettre en exploitation les reacteurs energetiques EDF1 - EDF2 - EDF3. Le memoire decrit comment, avant tout demarrage du reacteur, les essais effectues, en particulier ceux concernant l'installation de recuperation d'energie et le caisson, ont permis d'abreger la phase de montee en puissance. (auteur)

  8. International nuclear panorama; Panorama nucleaire international

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    This document takes stock on the nuclear power in the world. The nuclear power place in the energy policy of many countries is discussed and the development programs are presented. It seems that the USA attitude, favourable to a development of nuclear power plants, had an real impact on the other countries energy policy. (A.L.B.)

  9. Nuclear Safety. 1997; Surete Nucleaire. 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-01-19

    A quick review of the nuclear safety at EDF may be summarized as follows: - the nuclear safety at EDF maintains at a rather good standard; - none of the incidents that took place has had any direct impact upon safety; - the availability remained good; - initiation of the floor 4 reactor generation (N4 unit - 1450 MW) ensued without major difficulties (the Civaux 1 NPP has been coupled to the power network at 24 december 1997); - the analysis of the incidents interesting from the safety point of view presents many similarities with earlier ones. Significant progress has been recorded in promoting actively and directly a safe operation by making visible, evident and concrete the exertion of the nuclear operation responsibility and its control by the hierarchy. The report develops the following chapters and subjects: 1. An overview on 1997; 1.1. The technical issues of the nuclear sector; 1.2. General performances in safety; 1.3. The main incidents; 1.4. Wastes and radiation protection; 2. Nuclear safety management; 2.1. Dynamics and results; 2.2. Ameliorations to be consolidated; 3. Other important issues in safety; 3.1. Probabilistic safety studies; 3.2. Approach for safety re-evaluation; 3.3. The network safety; 3.4. Crisis management; 3.5. The Lifetime program; 3.6. PWR; 3.7. Documentation; 3.8. Competence; 4. Safety management in the future; 4.1. An open future; 4.2. The fast neutron NPP at Creys-Malville; 4.3. Stabilization of the PWR reference frame; 4.4. Implementing the EURATOM directive regarding the radiation protection standards; 4.5. Development of biomedical research and epidemiological studies; 4.6. New regulations concerning the liquid and gaseous effluents; 5. Visions of an open future; 5.1. Alternative views upon safety ay EDF; 5.2. Safety authority; 5.3. International considerations; 5.4. What happens abroad; 5.5. References from non-nuclear domain. Four appendices are added referring to policy of safety management, policy of human factors in NPPs, technical incidents, and human factor incidents.

  10. Nuclear questions; Le nucleaire en questions

    Energy Technology Data Exchange (ETDEWEB)

    Berg, Eugene

    2012-02-15

    Civilian and military nuclear questions fill a multitude of publications these days, especially after the Japanese tsunami and the Fukushima disaster. The author analyses some of them and highlights the links between civil and military nuclear industries, the realities of the nuclear cycle and related industrial questions before concluding on the controversial issue of weapons and their proliferation potential

  11. The nuclear threat; La menace nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Tertrais, Bruno

    2011-01-26

    For a long time, a small group of big powers has been the only holder of nuclear weapons (US, USSR, Great Britain, France and China). Since then, new weapons have come out on the geopolitical scene: Israel, India, Pakistan, and some others remain uncertain and generate a worrying atmosphere (North Korea, Iran..). But what is the real risk with nuclear proliferation? Should we dread about it? Is nuclear terrorism a real threat? What are the political stakes of nuclear weapons? Is disarmament a real solution? These are some of the questions that the author answers in a precise and clear manner in this book. Contents: 1 - from monopoly to proliferation: who owns nuclear weapons today, why is it so coveted, is it easy to make one?; 2 - the newcomers: what do we really know about the Iranian nuclear programme, Iran and North Korea: between negotiation and confrontation; 3 - international control and regulation: do we have reliable information, how do we know what we know, Iraq: was there a 'lie' somewhere, who are the states who have renounced nuclear weapons?; 4 - the future: is there still a nuclear warfare risk, what if Pakistani weapons fall into islamic hands, is nuclear terrorism a fantasy or a real risk?

  12. Nuclear Safety Charter; Charte Surete Nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-07-01

    The AREVA 'Values Charter' reaffirmed the priority that must be given to the requirement for a very high level of safety, which applies in particular to the nuclear field. The purpose of this Nuclear Safety Charter is to set forth the group's commitments in the field of nuclear safety and radiation protection so as to ensure that this requirement is met throughout the life cycle of the facilities. It should enable each of us, in carrying out our duties, to commit to this requirement personally, for the company, and for all stakeholders. These commitments are anchored in organizational and action principles and in complete transparency. They build on a safety culture shared by all personnel and maintained by periodic refresher training. They are implemented through Safety, Health, and Environmental management systems. The purpose of these commitments, beyond strict compliance with the laws and regulations in force in countries in which we operate as a group, is to foster a continuous improvement initiative aimed at continually enhancing our overall performance as a group. Content: 1 - Organization: responsibility of the group's executive management and subsidiaries, prime responsibility of the operator, a system of clearly defined responsibilities that draws on skilled support and on independent control of operating personnel, the general inspectorate: a shared expertise and an independent control of the operating organization, an organization that can be adapted for emergency management. 2 - Action principles: nuclear safety applies to every stage in the plant life cycle, lessons learned are analyzed and capitalized through the continuous improvement initiative, analyzing risks in advance is the basis of Areva's safety culture, employees are empowered to improve nuclear Safety, the group is committed to a voluntary radiation protection initiative And a sustained effort in reducing waste and effluent from facility Operations, employees and subcontractors are treated alike, and a high level Of know-how is supported by training and skills maintenance. 3 - Transparency and reporting: Areva endeavors to provide reliable and relevant information enabling an objective assessment of the status of nuclear safety in its facilities (incident reporting, annual report of the general inspectorate, annual reporting on occupational safety during nuclear facility operations). 4 - Glossary.

  13. Nucleaire et Energies Nr 66 - July 2015

    International Nuclear Information System (INIS)

    Lenail, Bernard; Ducroux, Guy; Salanave, Jean-Luc; Seyve, Claude; Simonnet, Jacques; Justin, Francois; Darricau, Aime; Raisonnier, Daniele

    2015-07-01

    After a first article recalling the creation of Areva and difficulties faced by this company which resulted in some kind of backward step, two articles address evolutions in the energy sector: an overview of recent evolutions (USA to become the first oil producer in the world, the OPEC policy, the distribution of nuclear energy production in the world, world consumption in 2014, the French law on energy transition, the dilemma associated with energy transition in Germany, regulated gas prices in France), and a discussion of the perspective for electricity by 2050 (100 per cent renewable? And why not 100 per cent nuclear?). Four articles concern nuclear activities: recent events in the mining and fuel fabrication sectors (an uranium bank in Kazakhstan, contract for Areva in Ukraine, uranium enrichment in South Korea, Saudi Arabia, India, China, Japan, USA), recent events regarding nuclear reactors (in France, UK, Sweden, Czech Republic, Russia, Turkey, South Korea), overview of activities and events related to the back-end of the fuel cycle (in France, Germany, China, USA and Japan), and a presentation of Savannah River MFFF plant (MOX Fuel Fabrication Facility). Two article address issues related to nuclear and society: a discussion on the possibility to eat irradiated food products, and the issue of the Iranian nuclear industry with respect to non-proliferation. A last article briefly discusses some terminological confusion between energy and electricity, and between produced energy and available power

  14. Nucleaire et Energies Nr 68 - June 2016

    International Nuclear Information System (INIS)

    Lenail, Bernard; Ducroux, Guy; Seyve, Claude; Simonnet, Jacques; Dupont, Jean-Francois; Salanave, Jean-Luc; Justin, Francois; Greneche, Dominique; Lepine, Gerard; Raisonnier, Daniele

    2016-06-01

    After a first article which comments the situation of EDF which is a serious matter of concern, notably due to the current context for the energy sector and market, and which notably comments the issue of the Hinkley Point project, an article proposes an overview of recent evolutions (oil price recent evolutions, perspectives for gas and coal, the abundance and availability of hydroelectric energy). Three articles concern nuclear activities: recent events about reactors (EU policy, decisions, projects and events in Switzerland, Sweden, UK about Hinkley Point, Fessenheim, Chernobyl, Poland, Europe about reactor lifetime extension, Russia, in Saudi Arabia and South Korea about the Korean APR-1400 technology, in Bangladesh, in India, Japan and USA), about the back-end of the fuel cycle and decommissioning activities (brief focus on the Cigeo project, foreign storages, discussion of the warehousing-transport issue, dismantling activities in France, recycling in France, Russia, China, Taiwan and the UK, evolution of the MFFF plant in Savannah River), and a comment of the main qualities of nuclear energy. Articles comment issues concerning the relationship between nuclear and society with a comment on the French approach (nuclear and precaution principle, anti-nuclear position of French media, crucial role of operators for nuclear safety), and a comment on the evolution of human lifetime expectation statistics in France and its possible relationship with technology when taking accidents related to energy sources into account. An article analyses the German situation with respect to energy. A last article briefly discusses some terminological confusion between energy and electricity, and between produced energy and available power

  15. Nucleaire et Energies Nr 65 - March 2015

    International Nuclear Information System (INIS)

    Lenail, Bernard; Ducroux, Guy; Seyve, Claude; Simonnet, Jacques; Justin, Francois; Salanave, Jean-Luc; Raisonnier, Daniele

    2015-03-01

    After a first brief article about the difficult situation faced by Areva, and an article about the Japanese situation four years after the Fukushima accident and the progressive restarting of reactors, an article proposes an overview of recent evolutions and events in the energy sector: the sharp decrease of oil prices and its consequences for Total and the European Union. Three articles concern nuclear activities: recent events in the mining and fuel fabrication sectors (perspectives, restructuring in the USA, contracts for Areva and EDF), overview of the situation of reactors (with perspective for the installed power by 2050, unclear perspectives in France, projects in the UK in Hinkley Point, Moorside, and Wylfa, situation in Belgium, Hungary and Russia, contracts for Areva and EDF, situation in Taiwan, India, South Korea, Japan, USA, South Africa), overview of activities and events related to the back-end of the fuel cycle and to decommissioning in different countries (recycling activities in France, decommissioning in France and in the UK, warehousing in France and Germany, a new warehousing system to be approved in the USA, events related to storage activities). An article discusses issues related to the lifetime of French nuclear reactors, and another one discusses the identification of electric power costs and ways to compare them. A last article briefly discusses some terminological confusion between energy and electricity, and between produced energy and available power

  16. Nuclear raw materials; Matieres premieres nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Cameron, J. [Division of Nuclear Power and Reactors, International Atomic Energy Agency, Vienna (Austria)

    1970-01-15

    It is clear that in the next decades there will be a substantial and increasing demand for uranium to fuel nuclear power stations. In a developing country, the discovery and development of uranium resources can be of importance either for the development of national nuclear power or for the commercial export of uranium. As the time taken between the start of a uranium exploration program and the uranium production stage.may be of the order of 6 - 10 years, it is now opportune to start new exploration so that advantage of the increased demand in the mid-1970s may be achieved. Thorium will also be of interest, but in the more distant future when the thorium cycle for advanced converters and breeder reactors is fully developed [French] Il est certain qu' au cours des prochaines décennies la demande d'uranium pour les centrales nucléaires sera importante et ne cessera de croître. Dans un pays en voie de développement, la découverte et la mise en valeur de ressources d'uranium peut avoir une grande importance, soit en vue de produire de l'énergie nucléoélectrique, soit en vue d'exporter l'uranium. Etant donné que les délais entre le démarrage d'un programme de prospection de l'uranium et le début de la production peuvent être de l'ordre de six ans, il est actuellement opportun de commencer les opérations d'exploration pour pouvoir profiter de la demande accrue qui s' affirmera vers le milieu de la prochaine décennie. Le thorium présentera aussi un certain intérêt, mais à plus long terme. Il faut pour cela que le cycle du thorium pour convertisseurs avancés et surgénérateurs ait été pleinement développé. (author)

  17. Critical experiments and nuclear calculations - LAMPRE-I; Experiences critiques et calculs nucleaires concernant le LAMPRE-I; Kriticheskie opyty i yadernye raschety - LAMPRE-I; Experimentos criticos u calculos nucleares relativos al LAMPRE-I

    Energy Technology Data Exchange (ETDEWEB)

    Battat, M E [Los Alamos Scientific Laboratory, University of California, Los Alamos, NM (United States)

    1962-03-15

    As part of a programme to develop plutonium fuels for fast-breeder reactors, the Los Alamos Scientific Laboratory has constructed and is operating a 1-MW sodium-cooled test reactor whose core contains a molten alloy of plutonium andiron (90 at. % Pu, 10 at. % Fe, m.p. 410 deg. C). Reactivity control is provided by the use of a stainless-steel reflector and four nickel control-rods located external to the core. Experiments have been performed at core temperatures (isothermal) of 80, 160 and 480 deg. C to determine critical mass and reflector worth at each of these temperatures. Control-rod worths, from period measurements, and temperature coefficient of reactivity were also measured. Calculations have been made, using the S{sub n} method for solving the neutron transport problem, to determine the basic nuclear parameters of the system. The comparison between calculated and measured values of parameters such as temperature coefficient, control-element worths, and critical mass is also of interest in evaluating the reliability of the design calculations. (author) [French] Un reacteur d'essais de 1 MW refroidi au sodium, dont le coeur contient un alliage fondu de plutonium et defer (90 at. % Pu, 10 at. % Fe, p. f. 410 deg. C), a ete construit et est en fonctionnement au Laboratoire scientifique de Los Alamos, dans le cadre d'un programme d'etudes sur les combustibles au plutonium pour reacteurs surgenerateurs a neutrons rapides. Le controle de la reactivite est assure au moyen d'un reflecteur en acier inoxydable et de quatre barres de controle en nickel, a l'exterieur du coeur. On a fait des experiences a des temperatures du coeur de 80, 160 et 480 deg. C afin de determiner la masse critique et la quantite de reflecteur qui correspond a chacune de ces temperatures. On a aussi mesure l'efficacite des barres de controle, a partir de mesures de periode, ainsi que le coefficient thermique de reactivite. Afin de determiner les parametres nucleaires de base du reacteur, on a

  18. Contribution to the study and use of ionisation chambers for nuclear reactor control (1965); Contribution a l'etude et a l'utilisation des chambres d'ionisation pour le controle des reacteurs nucleaires (1965)

    Energy Technology Data Exchange (ETDEWEB)

    Duchene, J [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1961-02-15

    high-power reactors. (author) [French] Les chambres d'ionisation sont actuellement les detecteurs les mieux adaptes au controle des reacteurs nucleaires par des mesures neutroniques. Nous avons cru bon de rappeler quelques generalites concernant la dynamique des reacteurs, les differents procedes de detection des neutrons, le fonctionnement des chambres d'ionisation et les methodes de mesure utilisees. Notre contribution aux techniques de controle des reacteurs consiste d'une part en une tentative de synthese des facteurs intervenant dans le fonctionnement des chambres d'ionisation, l'etude de ces facteurs, et d'autre part l'elaboration de chambres d'ionisation a fission et a bore permettant de suivre la marche d'un reacteur du demarrage jusqu'a la puissance maximale. Dans le domaine des chambres a fission, nous avons en particulier ameliore les techniques de depot d'oxyde d'uranium sur l'aluminium et realise la mise au point de depots par electrolyse sur d'autres metaux: acier inoxydable, cuivre, molybdene, nickel, tantale, titane, kovar, tungstene et beryllium. Nous avons elabore plusieurs types de chambres a fission servant au demarrage des reacteurs: un type de performances moyennes actuellement utilise dans les piles francaises un type a haute sensibilite un type a haute temperature qui a fonctionne jusqu'a 600 deg. C. En ce qui concerne les chambres a bore, nous avons etudie les perturbations apportees dans les mesures par l'exposition des chambres a d'importants flux de neutrons et a un rayonnement {gamma} intense. Cette exposition produit une modification des proprietes des materiaux constitutifs et la production dans les chambres d'un bruit de fond qui peut gener considerablement les mesures neutroniques. Nous avons montre que la technique de compensation permettait de limiter l'importance de ce bruit de fond et d'augmenter ainsi la plage de fonctionnement des chambres d'ionisation classiques destinees aux mesures de puissance. Enfin, nous avons realise deux

  19. Contribution to the study of molecular movements in cyclohexane by electron spin resonance and electron-nuclear double resonance using a radical probe; Contribution a l'etude des mouvements moleculaires dans le cyclohexane par resonance paramagnetique electronique et double resonance electronique-nucleaire a l'aide d'une sonde radicalaire

    Energy Technology Data Exchange (ETDEWEB)

    Volino, F [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1969-07-01

    Solutions of stable free radicals of the nitroxide type have been studied as a function of temperature. In the plastic or globular state, the cyclohexane molecules have rapid rotational and diffusional movements. They transmit this movement to dissolved free radicals. Conversely, measurements by electron spin resonance of the absolute movement of the radicals, and by electron nuclear double resonance of their movement relative to the cyclohexane molecules give very precise methods for local analyses of the movement present in the cyclohexane matrix. The principle of these techniques makes up the 'radical probe method'. (author) [French] Des solutions de radicaux libres stables, du type nitroxyde dans le cyclohexane ont ete etudiees, en fonction de la temperature. Les molecules de cyclohexane, dans l'etat plastique ou globulaire, sont animees de mouvements rapides de rotation sur elles-memes et de diffusion. Elles transmettent leur mobilite aux radicaux libres dissous. Reciproquement, la mesure du mouvement absolu des radicaux, a l'aide de la resonance paramagnetique electronique, et celle du mouvement relatif des radicaux et des molecules de cyclohexane par double resonance electronique-nucleaire, constituent des methodes tres precises pour analyser localement les mouvements presents dans la matrice de cyclohexane. Ce principe et ces techniques constituent la 'methode de la sonde radicalaire'. (auteur)

  20. Synthesis and purification of some alkyl phenanthrenes and presentation of their infrared, ultraviolet, nuclear magnetic resonance and mass spectra; Synthese et purification de quelques alcoylphenanthrenes et presentation ds leurs spectres d'absorption infrarouge, ultraviolette, de resonance magnetique nucleaire et de masse

    Energy Technology Data Exchange (ETDEWEB)

    Persaud, K. [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1965-01-01

    We have carried out the synthesis of: - phenanthrene - its five monomethyl derivatives - three dimethyl derivatives - two trimethyl derivatives. We have then purified these products as well as a certain number of others obtained from various sources. We have been able to obtain in the majority of cases, a purity of 99.5 per cent or over, these figures being obtained by low voltage mass spectrometry. Finally we have recorded the infrared, ultraviolet, nuclear magnetic resonance and mass spectra of these products for which an atlas has been drawn up. (author) [French] Nous avons realise la synthese: - du phenanthrene - de ses cinq derives monomethyles - de trois de ses derives dimethyles - de deux de ses derives trimethyles. Nous avons ensuite purifie ces produits ainsi qu'un certain nombre d'autres que nous avons obtenus de sources differentes. Nous avons pu atteindre, dans la plupart des cas, une purete egale ou superieure a 99,5 pour cent, chiffres determines par la spectrometrie de masse a basse tension. Enfin, nous avons enregistre les spectres infrarouges, ultraviolets, de resonance magnetique nucleaire et de masse de ces produits dont nous avons fait un atlas. (auteur)

  1. Communications Received from Certain Member States Regarding Guidelines for Transfers of Nuclear-related Dual-use Equipment, Materials, Software and Related Technology; Communications recues de certains Etats Membres concernant les directives applicables aux transferts d'equipements, de matieres et de logiciels a double usage dans le domaine nucleaire, ainsi que de technologies connexes

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-04-10

    The Director General of the International Atomic Energy Agency has received Notes Verbales, dated 1 December 2005, from the Resident Representatives to the Agency of Argentina, Australia, Austria, Belarus, Belgium, Brazil, Bulgaria, Canada, Croatia, Czech Republic, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Japan, Republic of Korea, Latvia, Lithuania, Luxembourg, Malta, the Netherlands, New Zealand, Poland, Portugal, Slovenia, South Africa, Spain, Sweden, Switzerland, Turkey, Ukraine, the United Kingdom of Great Britain and Northern Ireland and the United States of America, relating to transfers of nuclear-related dual-use equipment, materials, software and related technology [French] Le Directeur general de l'Agence internationale de l'energie atomique a recu des notes verbales datees du 1er decembre 2006 des representants permanents aupres de l'Agence des Etats suivants : Afrique du Sud, Allemagne, Argentine, Australie, Autriche, Belarus, Belgique, Bresil, Bulgarie, Canada, Croatie, Espagne, Estonie, Etats-Unis d'Amerique, Finlande, France, Grece, Hongrie, Irlande, Italie, Japon, Lettonie, Lituanie, Luxembourg, Malte, Nouvelle-Zelande, Pays-Bas, Pologne, Portugal, Republique de Coree, Republique tcheque, Royaume-Uni de Grande-Bretagne et d'Irlande du Nord, Slovenie, Suede, Suisse, Turquie et Ukraine, au sujet des transferts d'equipements, de matieres et de logiciels e double usage dans le domaine nucleaire, ainsi que de technologies connexes.

  2. Communications of 15 November 1999 Received from Member States Regarding the Export of Nuclear Material and of Certain Categories of Equipment and Other Material; Communications En Date Du 15 Novembre 1999 Recues D'Etats Membres Concernant L'Exportation De Matieres Nucleaires Et De Certaines Categories D'Equipements Et D'Autres Matieres

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-15

    The Director General of the International Atomic Energy Agency has received letters of 17 October 1996 from the Resident Representatives of Argentina, Australia, Austria, Bulgaria, Canada, the Czech Republic, Denmark, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Japan, Republic of Korea, the Netherlands, Norway, Poland, Portugal, Romania, the Russian Federation, the Slovak Republic, South Africa, Spain, Sweden, the United Kingdom, and the United States of America, concerning the export of nuclear material and of certain categories of equipment and other material [French] Le Directeur general de l'Agence internationale de l'energie atomique a recu des lettres datees du 15 novembre 1999 que les representants permanents des pays suivants lui ont adressees au sujet de l'exportation de matieres nucleaires et de certaines categories d'equipements et d'autres matieres : Afrique du Sud, Allemagne, Argentine, Australie, Autriche, Belgique, Bulgarie, Canada, Coree (Republique de), Danemark, Espagne, Etats-Unis d'Amerique, Finlande, France, Grece, Hongrie, Irlande, Italie, Japon, Luxembourg, Norvege, Pays-Bas, Pologne, Portugal, Republique slovaque, Republique tcheque, Roumanie, Royaume-Uni, Suede, Suisse, Turquie et Ukraine.

  3. Contribution to the study of molecular movements in cyclohexane by electron spin resonance and electron-nuclear double resonance using a radical probe; Contribution a l'etude des mouvements moleculaires dans le cyclohexane par resonance paramagnetique electronique et double resonance electronique-nucleaire a l'aide d'une sonde radicalaire

    Energy Technology Data Exchange (ETDEWEB)

    Volino, F. [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1969-07-01

    Solutions of stable free radicals of the nitroxide type have been studied as a function of temperature. In the plastic or globular state, the cyclohexane molecules have rapid rotational and diffusional movements. They transmit this movement to dissolved free radicals. Conversely, measurements by electron spin resonance of the absolute movement of the radicals, and by electron nuclear double resonance of their movement relative to the cyclohexane molecules give very precise methods for local analyses of the movement present in the cyclohexane matrix. The principle of these techniques makes up the 'radical probe method'. (author) [French] Des solutions de radicaux libres stables, du type nitroxyde dans le cyclohexane ont ete etudiees, en fonction de la temperature. Les molecules de cyclohexane, dans l'etat plastique ou globulaire, sont animees de mouvements rapides de rotation sur elles-memes et de diffusion. Elles transmettent leur mobilite aux radicaux libres dissous. Reciproquement, la mesure du mouvement absolu des radicaux, a l'aide de la resonance paramagnetique electronique, et celle du mouvement relatif des radicaux et des molecules de cyclohexane par double resonance electronique-nucleaire, constituent des methodes tres precises pour analyser localement les mouvements presents dans la matrice de cyclohexane. Ce principe et ces techniques constituent la 'methode de la sonde radicalaire'. (auteur)

  4. A study of filtering problems of background noise in nuclear spectrometry, improvement of signal-to-noise ratio, and of pulse characteristics produced by the optimum predictor device; Etude de problemes de filtrage de bruit de fond en spectrometrie nucleaire, amelioration du rapport signal sur bruit et des caracteristiques de l'impulsion mise en forme par le dispositif du predicteur optimum

    Energy Technology Data Exchange (ETDEWEB)

    Benda, J [Commissariat a l' Energie Atomique, 91 - Saclay (France). Centre d' Etudes Nucleaires

    1967-05-01

    The purpose of nuclear spectrometry is the precise measurement of particles energy. The resolving power of a spectrometer design is an important factor. Two main phenomena are involved in the limitation of this resolving power: The statistical fluctuations of the detector itself, and the background noise. For a given noise, the theory of filters enables the calculation of networks specially designed for the improvement of signal to noise ratio. The proposed system should lead to an improvement of 10.5 per cent of this ratio. Experiments have confirmed this theoretical estimation. The predictor device also makes possible the obtaining of shortened pulses. (author) [French] Les mesures en spectrometrie nucleaire ont pour but la determination precise de l'energie des particules. Le pouvoir de resolution d'une chaine de spectrometrie est une caracteristique importante. Deux phenomenes principaux concourent a limiter ce pouvoir de resolution: les fluctuations statistiques du detecteur et le bruit de fond. Pour un bruit de fond donne, la theorie des filtres permet de calculer des reseaux susceptibles de modifier le rapport signal sur bruit. Le systeme propose permet d'ameliorer de 10.5 pour cent ce rapport lorsqu'on se place dans les conditions optimales. Les resultats experimentaux confirment les previsions. Le dispositif predicteur permet aussi un raccourcissement de l'impulsion dans le temps. (auteur)

  5. Contribution to the study of {beta} disintegration and of nuclear structure using experiments on certain {beta}-{gamma} cascades: 198{sub Au}, 86{sub Rb}, 170{sub Tm}; Contribution a l'etude de la desintegration beta et a l'etude de la structure nucleaire a l'aide d'experiences sur certaines cascades beta-gamma: 198{sub Au}, 86{sub Rb}, 170{sub Tm}

    Energy Technology Data Exchange (ETDEWEB)

    Lachkar, J. [Commissariat a l' Energie Atomique, Bruyeres-le-Chatel (France). Centre d' Etudes; Paris-11 Univ., fabulte des Sciences 91 - Orsay (France)

    1969-07-01

    {beta}{gamma} directional angular correlations and shapes of inner beta spectra leading to the first excited level of the final nucleus enable one to determine the nuclear matrix elements typical of the {beta} transition. In the three observed first forbidden cases: {sup 170}Tm, {sup 86}Rb, {sup 198}Au, these matrix elements do not confirm the independent shell model theory. Other hypotheses are then suggested and discussed. (author) [French] Les experiences de correlation angulaire {beta}{gamma} et l'etude du spectre {beta} conduisant au premier niveau excite du noyau final permettent de determiner les elements de matrices nucleaires caracteristiques de cette transition. Dans les trois cas etudies (transitions une fois interdites): {sup 170}Tm, {sup 86}Rb, {sup 198}Au, ces elements de matrices ne peuvent etre retrouves a l'aide du modele en couches et a particules independantes. D'autres hypotheses sont alors emises et discutees. (auteur)

  6. Contribution to the study of {beta} disintegration and of nuclear structure using experiments on certain {beta}-{gamma} cascades: 198{sub Au}, 86{sub Rb}, 170{sub Tm}; Contribution a l'etude de la desintegration beta et a l'etude de la structure nucleaire a l'aide d'experiences sur certaines cascades beta-gamma: 198{sub Au}, 86{sub Rb}, 170{sub Tm}

    Energy Technology Data Exchange (ETDEWEB)

    Lachkar, J [Commissariat a l' Energie Atomique, Bruyeres-le-Chatel (France). Centre d' Etudes; Paris-11 Univ., fabulte des Sciences 91 - Orsay (France)

    1969-07-01

    {beta}{gamma} directional angular correlations and shapes of inner beta spectra leading to the first excited level of the final nucleus enable one to determine the nuclear matrix elements typical of the {beta} transition. In the three observed first forbidden cases: {sup 170}Tm, {sup 86}Rb, {sup 198}Au, these matrix elements do not confirm the independent shell model theory. Other hypotheses are then suggested and discussed. (author) [French] Les experiences de correlation angulaire {beta}{gamma} et l'etude du spectre {beta} conduisant au premier niveau excite du noyau final permettent de determiner les elements de matrices nucleaires caracteristiques de cette transition. Dans les trois cas etudies (transitions une fois interdites): {sup 170}Tm, {sup 86}Rb, {sup 198}Au, ces elements de matrices ne peuvent etre retrouves a l'aide du modele en couches et a particules independantes. D'autres hypotheses sont alors emises et discutees. (auteur)

  7. Comparative Studies of Chemical Effects following Nuclear Reactions and Transformations on Metal Organic Phenyl Compounds; Etudes Comparatives des Effets Chimiques Induits par les Reactions et les Transformations Nucleaires sur des Composes Phenylmetalliques; 0421 0420 0410 0414 ; Estudios Comparativos de los Efectos Quimicos de las Reacciones y Transformaciones Nucleares en Compuestos Fenil-Organometalicos

    Energy Technology Data Exchange (ETDEWEB)

    Merz, E.; Riedel, H. J. [Kernforschungsanlage, Juelich, Federal Republic of Germany (Germany)

    1965-04-15

    molecule by the nuclear recoil and the resulting excitation. The hypothesis is put forward that the kind and quantity of certain new radioactive species produced in connection with nuclear events is less a function of the nature and concentration of primary recoil fragments than are the ions, radicals and lattice defects imparted to the irradiated materials by secondary recoil effects (elastic and inelastic interactions) , including the peculiar influence of oxygen. (author) [French] Les auteurs ont etudie les effets chimiques provoques par les atomes chaud de recul resultant des reactions nucleaires dans les solides et dans les liquides en se fondant sur une vaste comparaison des produits des processus (n,{gamma}) et (n,2n) dans les composes phenyles du germanium, de l'etain, du plomb, de l'arsenic et de l'antimoine. En outre, ils ont compare les produits de recul radioactifs formes apres capture K dans le tetraphenyl- germanium-{sup 68}Ge avec les resultats du processus (n,{gamma}) dans le triphenylgalliumet du processus (n,p) sur le tetraphenylgermanium. Enfin, ils ont etudie la transition {beta}{sup -} dans laquelle {sup 77}Ge est remplace par {sup 77}As dans le compose. En appliquant differentes methodes de separation, par exemple la chromatographie d'adsorption sur alumine, l'echange d'ions et l'electrophorese, ils ont separe les divers produits de recul radioactifs et determine les rendements individuels. Ils ont constate que, dans les reactions nucleaires, les composes des metaux cites ayant des coordinats identiques forment pratiquement les memes classes.de produits de recul. Toutefois, pour la distribution des rendements, il y a des differences caracteristiques entre la reaction (n,{gamma}) et la reaction (n,2n). L'influence sur les rendements est a peine perceptible lorsque les irradiations ont lieu dans des liquides ou des solutions. Mais les differences trouvees pour les nouveaux composes formes par des transformations nucleaires sont frappantes, en ce qui

  8. Reports by the Parliamentary Office for scientific and technological assessments. Thursday, May 19, 2011. The French nuclear installations in front of natural risks; Comptes rendus de l' Office Parlementaire d'Evaluation des Choix Scientifiques et Technologiques. Jeudi 19 mai 2011. Les installations nucleaires francaises face aux risques naturels

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-05-15

    Members of the French Parliament, representatives of the French nuclear safety authority (ASN), of the Academy of Sciences, researchers, and associations argue on major natural risks and their evaluation, notably by referring to the earthquake and tsunami which caused the Fukushima accident. They discuss the predictability of these phenomena, and evoke the context and consequences of climate change. A representative of the Academy of Technologies discusses the risks of land-slips and dam failure, outlines that earthquakes only caused some cracks in dams, and evokes the legal context and organisation regarding dam safety. Possible effects of earthquakes in France are discussed. A second part addresses the way natural risks are taken into account in the protection of nuclear installations

  9. Lessons learned from the ASN Renal Educator Listserv and survey.

    Science.gov (United States)

    Hoenig, Melanie P; Shapiro, Evelyn; Hladik, Gerald A

    2013-06-01

    Nephrology ranks next to last in career choices among US medical school graduates. The American Society of Nephrology established a Workforce Committee to help address this issue. Surveys of US medical students indicate that experiences during kidney pathophysiology courses in the preclerkship years may impact their decision to consider a career in nephrology. In October of 2011, preclinical kidney physiology and pathophysiology course directors at US medical schools were surveyed about teaching methods, curricular content, resources, and institutional support for teaching to identify what worked well and what impairs their teaching efforts. A Listserv of these educators, the American Society of Nephrology Renal Educators Listserv, was used to electronically administer the survey. Course leaders from 62 of 114 (54.4%) surveyed medical schools responded. Most of these educators are nephrologists, but physiologists and other clinicians also lead courses; 60% of course directors noted that lectures are videotaped, resulting in decreased attendance. A range of resources is used: 68% use audience response systems, 16% use the simulation center, and none of the educators indicated use of social media (such as Twitter or Facebook); 50% of respondents receive no remuneration, and 68% receive no full-time equivalent for their efforts. Audience response systems, virtual microscopy, and flash animations were identified as valuable teaching tools. Course directors, during subsequent dialogue on the American Society of Nephrology Renal Educators Listserv, have cited incorporation of case scenarios and integration of clinical exposure during preclinical years as methods that inspired interest. Hopefully, adoption of such approaches will ultimately serve to stimulate interest in nephrology.

  10. Současný pohled na koenzym Q

    Czech Academy of Sciences Publication Activity Database

    Rauchová, Hana; Vokurková, Martina

    2009-01-01

    Roč. 103, č. 1 (2009), s. 32-39 ISSN 0009-2770 R&D Projects: GA MŠk(CZ) 1M0510 Institutional research plan: CEZ:AV0Z50110509 Keywords : coenzyme Q * mitochondria * dietary supplement Subject RIV: CE - Biochemistry Impact factor: 0.717, year: 2009

  11. Contribution to the experimental survey of the nuclear isomerism. Application of the deferred coincidences method to research and to the survey of metastable states of short period; Contribution a l'etude experimentale de l'isomerie nucleaire. Application de la methode des coincidences differees a la recherche et a l'etude d'etats metastables de periode courte

    Energy Technology Data Exchange (ETDEWEB)

    Ballini, R [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1953-06-15

    Various methods of the physics brought many informations on the nuclear elements which one can arrange some ponderable quantities, what is the case of the steady elements and some, unsteady elements, as most of natural radioelements. On the other hand, elements of shorter life duration, and notably those that are carried to an excited state, are more badly known, and one can get information to their consideration that by the mediator of the properties of the transitions that they undergo, when they give birth has best-known nuclear cash: among these transitions represent the isomeric transitions. The goal of this work is the survey of the isomeric transitions from metastable states of short period, included in the domain of the microsecond to some milliseconds. The method of the deferred coincidences has been put to the point and applied in this goal while using the advantages of the selectors to several channels, under two main aspects where the device to several channels was either a selector of time, either a selector of amplitudes. This method served to study the working of Geiger-Muller counter and to measure with precision the period of {sup 181}Ta{sup *} in of the varied experimental conditions. The adopted value is 17,2 {+-}0,2 {mu}s. This work also found an immediate practical application to the setting in evidence of very weak quantities of hafnium in zirconium, of which it constitutes a tenacious and difficult impurity to analyze by the ordinary ways. (M.B.) [French] Les diverses methodes de la physique ont apporte de nombreux renseignements sur les especes nucleaires dont on peut disposer en quantites ponderables, ce qui est le cas des especes stables et de certaines especes instables, comme la plupart des radioelements naturels. Par contre, les noyaux de duree de vie plus courte, et notamment ceux qui sont portes a un etat excite, sont plus mal connus, et on ne peut obtenir de renseignements a leur egard que par l'intermediaire des proprietes des

  12. Pointing Out Main Factors from Design, Construction and Operating Experience of Existing Nuclear Plants for Assisting in Shaping Future Nuclear Power Programmes; Les principaux criteres degages de l'etude, de la construction et de l'exploitation des centrales nucleaires existantes et leur interet pour l'elaboration des futurs programmes d'energie d'origine nucleaire; Ukazanie osnovnykh faktorov proektirovaniya, stroitel'stva i opyta ehkspluatatsii sushchestvuyutsikh atomnykh ehlektrostantsij, chto dolzhno pomoch' pri sostavlenii budushchikh programm atomnoj ehnergetiki; Principales consideraciones relativas al diseno, construccion y explotacion de centrales nucleares, encaminadas a facilitar la preparacion de programas futuros de energia nucleoelectrica

    Energy Technology Data Exchange (ETDEWEB)

    Dalla Volta, F. [Comitato Nazionale per l' Energia Nucleare, Rome (Italy)

    1963-10-15

    enseignements qui ont ete fournis, aux points de vue technique et economique, par l'etude, la construction et l'exploitation des premieres centrales nucleaires, et qui peuvent etre particulierement utiles pour l'implantation de nouvelles centrales de ce genre dans l'avenir, notamment eu egard aux conditions qui regnent en Italie. La technologie actuelle des reacteurs et les progres qu'elle continue de faire revelent une tendance marquee vers la reduction du cout, non seulement des cycles de combustible, mais aussi des elements de la centrale. Cette evolution se trouve d'ailleurs favorisee par la tendance croissante a construire des centrales plus grandes et par le fait que l'etude du developpement du reseau electrique semble indiquer que, sur le plan economique, il y a plus d' avantage ainstaller des centrales nucleaires plus puissantes que d'augmenter la puissance des centrales classiques. Se fondant sur l'experience acquise concernant l'etu de, la construction et l'essai des divers types de centrales existantes, l'auteur donne un apercu des principaux facteurs dont il convient de tenir compte lors de l'etablissement des programmes futurs. Il insiste sur le probleme de l'isolement, vu les incidences favorables que peut avoir sur le choix du site de la centrale la mise au point d'ecrans de protection tres surs, qui puissent etre construits sans augmentation sensible du prix de revient, en tirant notamment parti, pour resoudre certains aspects de ce probleme, des conditions particulieres qui se trouvent reunies en Italie. Quant a l'experience du fonctionnement de certaines centrales d'un modele eprouve, l'auteur examine dans quelle mesure ces installations peuvent etre construites sans difficulte et satisfaire la demande du reseau; il se refere ici egalement au role croissant qu'il est prevu d'attribuer a l'energie d'origine nucleaire en Italie. Enfin, l'auteur souligne a quel point le rassemblement et l'interpretation des donnees relatives aux trois centrales, qui doivent

  13. Operating Experience with Indian Point Nuclear Electric Generating Station; Experience d'exploitation de la centrale nucleaire d'Indian point; Opyt ehkspluatatsii Indian-pojntskoj yadernoj ehlektrostantsii; Experiencia adquirida con la explotacion de la central nucleoelectrica de Indian point

    Energy Technology Data Exchange (ETDEWEB)

    Beattie, W. C.; Freyberg, R. H. [Consolidated Edison Company of New York, Inc., New York, NY (United States)

    1963-10-15

    dont un grand nombre avaient leur origine dans le secteur ''classique'' de la centrale. Ce sont surtout des defectuosites du systeme de commande des barres de controle qui, dans le secteur nucleaire, ont contribue a la chute automatique des barres et aux retards dans la remise en marche apres arret. Le 14 novembre 1962, on a arrete la centrale pour proceder aux changements prevus dans les tuyauteries de la partie classique et pour apporter des modifications ou additions aux organes de commande des barres de reglage (installation d'un purgeur a azote sec pour les logements des organes de commande, afin de reduire les effets des fuites d'eau a travers les joints), n semble que c'etait la la cause principale du mauvais fonctionnement du systeme. La centrale a ete remise en service le 1er janvier 1963. Les essais, jusqu'a 100% de la puissance theorique a charge constante, etaient termines le 27 janvier 1963. Les resultats concordent parfaitement avec les previsions. De nouveaux essais pour etudier la maniere dont le reacteur repond a des variations subites de la demande se poursuivront au printemps 1963. (author) [Spanish] El grupo No. 1 de la central de Indian Point consta de un reactor de 585 MW(t), de agua a presion cuatro circuitos refrigerantes primarios con intercambiadores de calor horizontales, dos sobrecalentadores a petroleo de 500 000 kg/h y un turbogenerador de 275 000 kW. El combustible del reactor consiste en una mezcla de oxido de {sup 235}U totalmente enriquecido y de oxido de {sup 232}T. La central se encuentra a orillas del rio Hudson, a uno 40 km al norte de Nueva York. Debido a la proximidad de esa ciudad se adoptaron dispositivos especiales de seguridad intrinseca para evitar saltos bruscos de reactividad y- prevenir sus efectos radiologicos. La construccion quedo terminada en mayo de 1962. Se cargo el combustible en junio y el reactor alcanzo la criticidad inicial el 2 de agosto de 1962. En el curso del mismo mes, se efectuaron los ensayos de baja

  14. The Why and How of Nuclear Accident Dosimetry; Dosimetrie en cas d'Accident Nucleaire: Raison d'Etre et Modalites; 041e 0411 041e 0421 041d 041e 0412 0414 ; Dosimetria en Casos de Accidente Nuclear: Justificacion y Modalidades

    Energy Technology Data Exchange (ETDEWEB)

    Vallario, E. J.; Wasson, H. R. [United States Atomic Energy Commission, Washington, DC (United States)

    1965-06-15

    The objective of an effective nuclear accident dosimetry programme is to ensure that a means is provided for estimating the gamma neutron dose from a nuclear accident. In this connection, the limitation of the film badge is discussed, in addition to certain accident experiences which demonstrate the need for an effective accident dosimetry programme at facilities having a potential for nuclear accidents. Certain basic parameters should be considered in the development of an effective nuclear accident dosimetry programme. These are (a) a method for screening personnel involved in nuclear accidents, (b) a fixed system (primary unit) capable of determining first collision dose within some established degree of accuracy at its point of location, (c) the need for ''secondary units'', and (d) the need for a device worn by personnel which would afford spectrum and flux information to assist in dose extrapolation from the fixed unit to the location of man. The neutron component of the system should permit flux and spectral information in order to arrive at appropriate quality factors in the dose estimation. Accuracies should be established based upon the current state of the art. The gamma -ray component of the system should permit measuring gamma radiation within the biological area of interest, i. e. from 10 to 10{sup 3}r. Consideration for the number, placement and ease of recovery of accident units are indeed an integral part of an effective system of accident dosimetry. These considerations should enable reasonable data collection across the entire fission spectrum. (author) [French] L'objet d'un programme efficace de dosimetrie en cas d'accident nucleaire est d'evaluer la dose de rayons gamma et de neutrons emise lors d'un acccident nucleaire. Le memoire examine les limitations des dosimetres a film et expose les circonstances accompagnant certains accidents, lesquelles demontrent la necessite de prevoir un programme efficace de dosimetrie dans les installations ou

  15. Legal and Administrative Problems of Controlling the Disposal of Nuclear Wastes in the Sea; Problemes Juridiques et Administratifs Poses par le Controle de l'Elimination des Dechets Nucleaires dans la Mer; 041f 0420 041e 0414 ; Problemas Juridicos y Administrativos que Plantea el Control de la Evacuacion de Desechos Nucleares En El Mar

    Energy Technology Data Exchange (ETDEWEB)

    Hydeman, Lee M.; Berman, William H. [Atomic Energy Research Project, University of Michigan Law School (United States)

    1960-07-01

    The basic purpose of the paper is to present some approaches to multinational control of the sea disposal of nuclear wastes, considering both the type of international .control which may be appropriate and the means for accomplishing such control. First, the authors give a brief description of the kind of control which appears to be necessary in protecting public health against the hazards of the disposal of wastes in the sea. The second part consists of a general analysis of the legal problems posed by nuclear wastes. Emphasis is placed on the authority of coastal states to impose unilateral control on the disposal of wastes by other nations if such disposal might adversely affect their interests. The authors inquire into the adequacy of legal remedies as well as the possible rule of law regarding the prevention of damage from waste disposal and the apportionment of liability in the event that such damage does occur. The third part is an analysis of how other problems of control have been handled, both unilaterally and multilaterally. The final part consists of an inquiry into various means of internationally controlling the sea disposal of nuclear wastes. The role of existing international bodies in the maintenance of continuing administrative control at the international level is mentioned. (author) [French] Le but essentiel du memoire est d'exposer diverses facons d'envisager le probleme du controle multinational de l'evacuation des dechets nucleaires dans l'eau de mer, en examinant a la fois le type de controle international approprie et les moyens de le mettre en oeuvre. La premiere partie contiendra une description succincte du genre de controle qui semble necessaire pour la protection de la sante publique contre les effets de l'evacuation des dechets dans la mer. La deuxieme partie consistera en une analyse generale des problemes juridiques poses par. l'elimination des dechets nucleaires. Les auteurs traiteront particulierement du droit des Etats riverains

  16. The United States Atomic Energy Commission Programme of Nuclear Materials Management; Le Programme de Gestion des Matieres Nucleaires Applique par L'USAEC; Programma komissii po atomnoj ehnergii ssha v oblasti obrashcheniya s yadernymi materialami; El Programa de Administracion de Materiales Nucleares de la Comision de Energia Atomica de los Estados Unidos

    Energy Technology Data Exchange (ETDEWEB)

    George, D. E. [United States Atomic Energy Commission, Washington, DC (United States)

    1966-02-15

    Nuclear materials management as conceived by the US Atomic Energy Commission is defined and its development traced from 1943 to the present time. The general programme is outlined and its principal features discussed. Emphasis is placed on administration of those portions of the USAEC programme which pertain to the development and maintenance of quantity data, the establishment of internal controls and the evaluation of performance. The current techniques whereby transfer data are recorded and processed within the USAEC are discussed in some detail, as are the techniques for presentation of material balance reports which periodically summarize the transactions and the results of operations. The techniques used by the USAEC to ascertain the effectiveness of the nuclear materials management programmes of its operating contractors are also discussed. In addition to material being held by contractors which operate USAEC-owned plants and laboratories, there are large quantities of special nuclear material held under a wide variety of financial and administrative arrangements, e.g. under lease, private ownership, under contract with the USAEC where the user is financially liable for losses, as well as those where the risk of losses is taken by the USAEC. This divergence of circumstances causes significant variation in the emphasis and approach used by the AEC and this variation is noted. A brief summary of unresolved problem areas concludes the presentation. (author) [French] L'auteur definit la gestion des matieres nucleaires telle qu'elle est concue par l'USAEC et decrit son evolution depuis 1943 jusqu'a nos jours. Il expose le programme general et discute ses principales caracteristiques. Le memoire souligne les aspects administratifs des parties du programme qui ont trait a la preparation et la tenue a jour des donnees relatives aux quantites, a l'application de controles internes et a l'evaluation de l'efficacite des mesures prises. L'auteur commente en detail la

  17. Shippingport Atomic Power Station Operating Experience, Developments and Future Plans; La centrale nucleaire de Shippingport, experience de son fonctionnement et plans pour l'avenir; Shippingportskaya atomnaya ehlektrostantsij, opyt ehkspluatatsii, usovershenstvovaniya i plany na budushchee; Central nucleoelectrica de Shippingport; experiencia adquirida con su explotacton y programa de desarrollo

    Energy Technology Data Exchange (ETDEWEB)

    Feinroth, H. [Division of Reactor Development, United States Atomic Energy Commission, Washington, DC (United States); Oldham, G. M. [Shippingport Atomic Power Station, Duquesne Light Company, Pittsburgh, PA (United States); Stiefel, J. T. [Bettis Atomic Power.Labora Tory, Westinghouse Electric Corporation, Pittsburgh, PA (United States)

    1963-10-15

    design rating of 150 MW(e) gross and a first seed life of 10.000 effective full power hours (EFPH), Core 2 will have five and a half times the design energy output and twice the power density of Core 1. The Core 2 design is described and associated major developments in reactor physics, metallurgy, heat transfer and fluid flow, and fuel element manufacture, are summarized. Plans for decontamination of the reactor plant and for performing modifications to the plant in connection with the installation of the higher rated Core 2 are described. (author) [French] Les auteurs font le bilan des cinq annees de fonctionnement et d'essai de la centrale nucleaire de Shippingport; ils examinent les progres techniques actuels et l'avenir du programme de Shippingport. Ce programme vise a mettre au point la technologie fondamentale des reacteurs a eau legere pour permettre une reduction du prix de revient de l'energie d'origine nucleaire. La centrale nucleaire de Shippingport fonctionne depuis plus de 5 ans et s'est integree facilement dans un reseau d'interconnexion comme centrale de base ou comme centrale d'appoint. Les divers elements de la centrale se sont reveles d'un fonctionnement sur. Il n'y a pas eu de probleme de contamination ni d'elimination des dechets. On peut acceder facilement aux elements du circuit primaire de refroidissement pour l'entretien et, ce faisant, on a constate que les cartouches de combustible etaient intactes. Chacune des trois operations de rechargement effectuees depuis le demarrage de la centrale a pris moins de temps que la precedente. Recemment, la troisieme charge de combustible enrichi a ete mise en place en 32 journees de travail, soit environ le quart du temps necessaire pour le premier rechargement. Les auteurs exposent les conditions auxquelles doit satisfaire la formation du personnel et donnent un apercu des instructions ecrites en matiere d'administration, d'exploitation, etc., qui sont autant de facteurs essentiels du succes du programme de

  18. Contribution to the study of time-resolution in pulse electronics for nuclear physics: phase control circuits; Contribution a l'etude de la resolution en temps de l'electronique impulsionnelle pour physique nucleaire: les circuits de mise en phase

    Energy Technology Data Exchange (ETDEWEB)

    Cortet, J P [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1969-07-01

    Phase control circuits make it possible to improve quite markedly the time resolution in pulse electronics. They replace a random pulse, of which the time of arrival with respect to a reference zero is being measured, by another pulse whose phase is well determined with respect to that, of a clock taken as reference. The time spectrum of the output, delayed, can always be situated inside channels of width {delta}T defined by the clock. The time statistics of the events analyzed is always correct even if the transition time for the circuits defining the channels represents a large fraction of {delta}T: the coding of the time becomes perfect, The phase control circuits, used in precision chronometry, are widely applied in Nuclear Physics since the lime spectra obtained are representative, indirectly, of certain values which are required to be measured with great accuracy. A description is given of: the constitution and operation of phase control circuits; a chain with automatic analysis and automatic reading, built for testing these circuits. Finally the measurement results are given. (author) [French] Les circuits de mise en phase permettent d'ameliorer notablement la resolution en temps de l'electronique impulsionnelle. Ils substituent a une impulsion aleatoire, dont on cherche a mesurer l'instant d'arrivee par rapport a un instant pris pour origine, une autre impulsion dont la phase est bien determinee par rapport a celle d'une horloge prise comme reference. Le spectre temporel de sortie, retarde, peut toujours etre situe a l'interieur des canaux de largeur {delta}T, definis par l'horloge. La statistique temporelle des evenements analyses est toujours correcte, meme si la duree de transition des circuits definissant les canaux represente une grande fraction de {delta}T: le codage de temps devient parfait. Les circuits de mise en phase, utilises en chronometrie fine, sont tres employes en Physique Nucleaire car les spectres temporels oblenus sont representatifs

  19. Use of 14 MeV neutrons in activation analysis. Experiments carried out at the Grenoble nuclear research Centre (1963); Utilisation de neutrons de 14 MeV en analyse par activation. Experience realisee au Centre d'etudes nucleaires de Grenoble (1963)

    Energy Technology Data Exchange (ETDEWEB)

    Auboin, G; Guazzoni, P; Laverlochere, J [Commisariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1963-07-01

    The use of 14 MeV neutron irradiation makes it possible to extend the field of application of activation analysis to elements which cannot be activated in nuclear reactors (oxygen, boron, for example) or else to consider the possibility of 'portable' measurement units for routine analyses. With this aim, tests have been carried out for studying the sensitivity and interferences in the case of the dosing of oxygen in eleven different matrices using 150 and 300 kV SAMES accelerators producing 14 MeV neutrons by the reaction {sup 3}H (d, n) {sup 4}He. The sensitivity of the dosage methods for six writer elements has also been studied. The results obtained show that, for a neutron flux of 10{sup 10} n/4{pi}, the sensitivities vary from 100 {mu}g and 1 mg for oxygen in nine matrices (Be, Ta, Nb, Ti, Zr, Fe, Al, Sb, Si) and that it is possible to dose the six elements F, B, Y, Si, N, Al with sensitivities of between 1 an 1000 micrograms. (authors) [French] L'irradiation au moyen de neutrons de 14 MeV permet d'etendre le domaine d'application de l'analyse par activation a des elements non activables en reacteur nucleaire (oxygene, bore, par exemple) ou encore d'envisager des unites de dosage ''portables'' pour des analyses de routine. Dans ce but, des essais ont ete effectues pour etudier les sensibilites et les interferences dans le cas du dosage de l'oxygene dans onze matrices differentes, au moyen d'accelerateurs SAMES 150 et 300 kV. produisant les neutrons de 14 MeV par la reaction {sup 3}H (d, n) {sup 4}He. Des sensibilites de dosage ont egalement ete etudiees pour six autres elements. Les resultats obtenus montrent que, pour un flux de neutrons de 10{sup 10} n /4{pi}, les sensibilites varient entre 100 {mu}g et 1 mg, pour l'oxygene dans neuf matrices (Be, Ta, Nb, Ti, Zr, Fe, Al, Sb, Si) et qu'il est possible de doser les six elements F, B, Y, Si, N, Al avec des sensibilites se situant entre 1 et 1000 microgrammes. (auteurs)

  20. The Text of the Agreement between Belgium, Denmark, the Federal Republic of Germany, Ireland, Italy, Luxembourg, The Netherlands, the European Atomic Energy Community and the Agency in Connection with the Treaty on the Non-Proliferation of Nuclear Weapons; Texte de l'Accord entre la Belgique, le Danemark, la Republique Federale d' Allemagne, l'Irlande, l'Italie, le Luxembourg, les Pays-Bas, la Communaute Europeenne de l'En-Ergie Atomique et L'Agence En Application Du Traite Sur La Non-Proliferation Des Armes Nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1973-09-14

    The text of the Agreement, and of the Protocol thereto, between Belgium, Denmark, the Federal Republic of Germany, Ireland, Italy, Luxembourg, The Netherlands, the European Atomic Energy Community and the Agency in implementation of Article III (1) and (4) of the Treaty on the Non-Proliferation of Nuclear Weapons (reproduced in document INFCIRC/140) is reproduced in this document for the information of all Members [French] Le texte de l'Accord, ainsi que celui du Protocole qui y est joint, entre la Belgique, le Danemark, la Republique fdrale d'Allemae, l'Irlande, l'Italie, le Luxembourg, les Pays-Bas, la Communaute europenne de l'energie atomique et l'Agence condu en application des paragraphes 1 et 4 de l'article III du Traite sur la non proliferation des armes nucleaires sont reproduits dans le present document pour l'information de tous les Membres.

  1. HCTISN - Plenary extraordinary meeting on the 9 March 2012 - General consequences of the earthquake and tsunami; Status of Fukushima-Dai-ichi nuclear installations; The Fukushima accident, one year after: environmental and health situation in Japan; Protective actions undertaken by Japanese authorities; Support by AREVA to Japan after the Fukushima accident; What went on in Fukushima? Implementation of the IAEA nuclear safety action plan; Review of European stress tests by the peers; Opinion of the ASN on complementary safety assessments (CSAs); HCTISN - Reunion pleniere extraordinaire du 9 mars 2012: Consequences generales du seisme et du tusnami; Situation des installations nucleaires de Fukushima Dai-ichi; L'accident de Fukushima 1 an apres: situation environnementale et sanitaire au Japon; Les actions de protection engagees par les autorites japonaises; Aide apportee par AREVA au Japon suite a l'accident de Fukushima; Que s'est-il passe a Fukushima?

    Energy Technology Data Exchange (ETDEWEB)

    Kataoka, Susumu [Ambassade du Japon en France, 7 Avenue Hoche, 75008 Paris (France); Charles, T.; Champion, Didier [Institut de radioprotection et de surete nucleaire - IRSN, 31, avenue de la Division Leclerc, 92260 Fontenay-aux-Roses (France); Jean-Luc Godet [Autorite de surete nucleaire, 6, place du Colonel Bourgoin, 75012 Paris (France); ASN/DIS, 10, Route du Panorama, 92266 Fontenay-aux-Roses cedex (France); Arnaud GAY [Business Unit Valorisation - AREVA (France); Philippe Jamet [European Nuclear Safety Regulators Group - ENSREG, Autorite de surete nucleaire, 6, place du Colonel Bourgoin, 75012 Paris (France)

    2012-03-09

    This document contains Power Point presentations proposed during a plenary session of the High Committee transparency and information on nuclear safety (HCTISN). The contributions addressed the Fukushima accident (the earthquake and the tsunami, the technical consequences on the plant, the consequences on the environment and on health, the different actions undertaken in Japan to protect the population, the consequences on nuclear safety in other countries with notably the performance of stress tests or the organisation of complementary safety assessments on the French fleet of nuclear reactors

  2. The transparency associated with the nuclear fuel cycle

    International Nuclear Information System (INIS)

    2009-01-01

    This document presents the French national plan for the management of radioactive materials and wastes (PNGMDR - Plan national de gestion des matieres et dechets nucleaires), its elaboration process, its content in terms of nuclear fuel cycle. Then, it describes the control by the ASN of the nuclear fuel cycle, the associated installations, the concerned transports, the 'cycle consistency' approach and its limitations. Propositions are stated aiming at the improvement of the transparency associated with the fuel cycle: to use the PNGMDR, to extend the investigation on the cycle consistency to imported materials and wastes, to improve the transparency on radioactive material transport

  3. Non-Destructive Methods for Determining Burn-Up in Nuclear Fuel; Methodes Non Destructives d'Evaluation du Taux de Combustion dans le Combustible Nucleaire; Metody opredeleniya vygoraniya v yadernom toplive bez razrusheniya obraztsa; Metodos No Destructivos para Determinai el Grado de Combustion de los Elementos Combustibles Nucleares

    Energy Technology Data Exchange (ETDEWEB)

    McGonnagle, W. J. [Illinois Institute of Technology, Chicago, IL (United States)

    1966-02-15

    is of secondary importance and the cooling time is unimportant. Also, there is more precise nuclear data for the stable fission products. Of the stable isotopes produced during the fission process, zirconium, molybdenum, ruthenium, and neodymium appear to be the most useful. The proposed non-destructive methods using stable isotopes will be discussed. (author) [French] Il est a la fois utile et souhaitable d'utiliser des methodes non destructives pour proceder a la mesure quantitative du taux de combustion des elements combustibles d'un reacteur nucleaire. L'ideal serait de pouvoir analyser le combustible a l'aide d'une methode ne necessitant pas de renseignements particuliers sur les spectres des neutrons, le schema d'irradiation ou le temps de refroidissement. Les isotopes radioactifs et les isotopes stables resultant du processus de fission qui sont presents dans un element combustible irradie caracterisent son irradiation. Malheureusement, que l'analyse soit effectuee au moyen de methodes destructives ou non destructives, les resultats obtenus varient en fonction du spectre de neutrons, du schema d'irradiation et du temps de refroidissement. Deplus, l'absence de donnees nucleaires precises, comme les valeurs des section efficaces, influe sur tous les calculs qui peuvent etre effectues. L'analyse non destructive est egalement genee par la presence de champs de rayonnements intenses qui augmentent le bruit de fond. Il est difficile d'etablir des normes utiles et realistes. Bien que, dans l'etat actuel de la technique, les methodes non destructives n'aient pas toute la precision et l'exactitude voulues, elles presentent neanmoins un grand interet' notamment dans les cas ou il faut obtenir rapidement et economiquement une valeur approximative du taux de combustion. Plusieurs methodes non destructives d'evaluation du taux de combustion sont actuellement appliquees, a l'etude ou en projet. Plusieurs types de spectrometres sont utilises pour la mesure du rayonnement

  4. The System for Controlling Source and Special Nuclear Material at the Eurochemic Reprocessing Plant; Systeme de Controle des Matieres Nucleaires Brutes et Speciales a l'Usine de Traitement D'Eurochemic; Sistema kontrolya nad iskhodnym i spetsial'nym yadernym materialom na zavode evrokhimicheskoj kompanii po regeneratsii yadernogo topliva; Control de Materiales Nucleares Basicos y de Materiales Fisionables Especiales en la Planta de Regeneracion de la Eurochemic

    Energy Technology Data Exchange (ETDEWEB)

    Frenzel, W.; Schueller, W. [EUROCHEMIC, MOL (Belgium)

    1966-02-15

    Eurochemic is constructing a reprocessing plant near Mol (Belgium). The main characteristics of the plant and the different process steps are summarized. To maintain proper control of source and special nuclear material, the facilities of the company are divided into material balance areas. All transfers into and out of these areas are determined. Depending on their significance for the overall material balance, different precision requirements have been established according to a scale of significance which is briefly discussed. To adjust the book balance, physical inventories are periodically performed. The corresponding inventory procedures are outlined. The books used for nuclear materials accounting and the principles of the accounting system are summarized. (author) [French] La societe Eurochemic fait actuellement construire une usine de traitement chimique pres de Mol (Belgique). L'auteur indique succinctement les principales caracteristiques de l'usine et les differentes etapes du traitement. Pour assurer un controle correct des matieres nucleaires brutes et speciales, les installations d'Eurochemic sont divisees en secteurs de mesures. Tous les transferts entre ces secteurs de mesure sont determines quantitativement. Les mesures sont faites avec des degres de precision differents qui ont ete fixes en fonction de leur importance pour le bilan matieres general; les auteurs examinent brievement les criteres appliques a cette fin. Pour verifier le bilan, on procede periodiquement a des inventaires materiels. La facon dont sont menes ces inventaires est exposee dans ses grandes lignes. Les auteurs indiquent les livres utilises pour la comptabilite des matieres nucleaires et resument les principes du systeme comptable. (author) [Spanish] La compania Eurochemic esta construyendo una planta de regeneracion en Mol (Belgica). Los autores resumen las principales caracteristicas de la instalacion, y las distintas fases del proceso industrial. Para mantener un control

  5. The First Two Years of Operating Experience of the Kahl Nuclear Power Station; Experience acquise pendant les deux premieres annees de fonctionnement de la centrale nucleaire de Kahl; Opyt pervykh dvukh let ehkspluatatsii atomnoj ehlektrostantsii v Kale; Experiencia adquirida en los primeros cuatro anos de funcionamiento de la central nucleoelectrica de Kahl

    Energy Technology Data Exchange (ETDEWEB)

    Bruchner, H. J. [Aeg-Kernenergieanlagen, Frankfurt-am-Main (Germany); Weckesser, A. [Versuchs-Atomkraftwerk Kahl Gmbh, Kahl (Germany)

    1963-10-15

    , une boucle experimentale destinee a l'etude de la surchauffe nucleaire. (author) [Spanish] La central de Kahl constituye la primera central nucleoelectrica europea de propiedad privada, y funciona en carga desde junio de 1961. Esta equipada con un reactor de agua hi que trabaja en ciclo indirecto por circulacion natural. Su capacidad electrica neta asciende a 15 MW y hasta febrero de 1963 habia producido 140 millones de kWh. La memoria revisara la experiencia adquirida durante su funcionamiento, ante todo con el extenso programa de ensayos sobre el comportamiento transitorio y la exploracion gamma. Presentara datos acerca del resultado que han dado en funcionamiento ciertas partes de la central, tales como el dispositivo de accionamiento de las barras de control, el sistema de purificacion de los gases de escape y la turbina. Una vez terminado el programa de ensayos, la planta se exploto en carga basica durante algun tiempo a fin de reunir datos sobre el rendimiento del combustible en la ptactica. Una vez completada esta fase, se instalara en el reactor de Kahl un circuito experimental de sobrecalentamiento nuclear. (author) [Russian] Atomnaya ehlektrostantsiya v Kale, pervaya v Evrope chastnaya atomnaya ehlektrostantsiya, ehkspluatiruetsya pod nagruzkoj s iyunya 1961 goda. Na ehlektrostantsii ustanovlen reaktor s kipyashchej vodoj, kosvennym tsiklom i estestvennoj tsirkulyatsiej. Chistaya ehlektricheskaya moshchnost' reaktora sostavlyaet 15 mgvt. Do fevralya 1963 goda kolichestvo poluchennoj ehnergii sostavilo 140 mln. kvt.ch. Rassmotren opyt ehkspluatatsii, v chastnosti rasshirennaya programma ispytanij: naprimer,povedenie reaktora pri perekhodnom protsesse i kontrol' gamma-izlucheniya. Budut predstavleny rezul'taty izucheniya ehkspluatatsionnoj kharakteristiki nekotorykh komponentov ustanovki, naprimer sistemy privoda reguliruptsikh sterzhnej, sistemy udaleniya gaza i turbiny. Posle osushchestvleniya ehtoj programmy ispytanij ustanovka v techenie nekotorogo vremeni

  6. Separation of Graphitic Line in Debyegram of the Reactor Graphite; Separation de la raie graphitique dans le debyegramme du graphite nucleaire; Otdelenie linii grafita v debaiegramme reaktornogo grafita; Separacion de la linea grafitica en el diagrama de debye del grafito nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Pandic, B. [Institut Rudjer Boskovio, Zagreb, Yugoslavia (Croatia)

    1963-11-15

    The author sets forth a method for the determination of crystallite dimensions L{sub c} in reactor graphite. The method consists of the mathematical correction of the diffraction profile (002) obtained by means of a Philips diffractometer with scintillation counter. During the work CuK{sub {beta}} radiation is used. The convenience of using CuK{sub {beta}} radiation rather than that of a CuK{sub {alpha}} doublet is discussed. All instrumental errors except that of the sample adsorption are eliminated using corresponding slits. Sample adsorption is corrected mathematically. Highly symmetrical lines of graphitic and non-graphitic phase could be analytically separated from such corrected line profiles. Experimental error in the determination of the half-height and half-width of these lines does not exceed 5%. (author) [French] On a elabore une methode pour determiner la hauteur moyenne L{sub c} des cristallites du graphite nucleaire. Il s'agit d'une methode mathematique de correction du profil de la raie de diffraction (002), obtenu par le diffractometre Philips avec un compteur a scintillation. On a discute les avantages des rayons CuK{sub {beta}} par rapport au doublet CuK{sub {alpha}}. Le choix des ouvertures elimine toutes les erreurs, sauf l'erreur d'absorption dans les echantillons, que l 'on ecarte mathematiquement. Les raies de diffraction pures et tres symetriques des phases graphitique et non graphitique peuvent etre separees du profil corrige de cette facon. L'incertitude dans la mesure de la demi-largeur de ces raies n'est pas superieure a 5%. (author) [Spanish] El autor de la memoria expone un metodo para determinar la altura media Lc de las cristalitas del grafito nuclear. Consiste en corregir matematicamente el perfil de la linea de difraccion (002) obtenido con un difractometro Philips y un contador de centelleo. En la memoria se explican las ventajas que la radiacion CuK{sub {beta}} ofrece sobre el doblete CuK{sub {alpha}} Si se elige correctamente la

  7. Problems to be Expected in Disposing of Fission Products from a Possible Nuclear Power Programme; Problemes Eventuels d'Elimination des Produits de Fission dans les Futures Centrales Nucleaires; 0412 0415 0420 041e 042f 0414 ; Problemas que Puede Plantear la Evacuacion de Productos de Fision Resultantes de la Ejecucion de un Programa de Produccion de Energia de Origen Nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Dickson, G. K. [Cenral Technical Services, Engineering and Development Group, United Kingdom Atomic Energy Authority, Risley (United Kingdom)

    1960-07-01

    typical British nuclear power programme covering the next few decades is examined. The types of reactor to be erected and the types of fuel to be initially used in them are well appreciated but of course the author's conclusions will necessarily become less certain with the passage of time. The chemical processes which must be applied to irradiated fuels will depend on the type of fuel, its burn-up etc., and so will change during the period under review. Consideration is therefore given to the quantities of fission products and heavy isotopes which may be produced, the forms in which they may leave the chemical processing streams and the methods available for handling them safely, either by storage or by disposal. (author) [French] L'auteur examine un programme d'energie nucleaire caracteristique pour la Grande-Bretagne et s'etendant sur les prochaines decennies. Il donne une evaluation fort judicieuse des types de reacteurs dont la construction est envisagee et des genres de combustibles qu'il est question d'y utiliser pendant la periode initiale; toutefois, ses conclusions auront avec le temps de moins en moins de valeur. En effet, le traitement chimique auquel on devra soumettre le combustible irradie depend du genre de ce dernier, de son taux de combustion, etc.; il subira inevitablement des modifications au cours de la periode consideree. L'auteur tient donc compte des quantites de produits fissiles et d'isotopes lourds qu'il sera possible de produire, des formes sous lesquelles ils pourront se presenter a la fin du traitement chimique et des methodes existantes permettant d'assurer leur manipulation sans danger en vue de leur stockage ou de leur elimination. (author) [Spanish] Esta memoria estudia un programa britanico caracteristico de produccion de energia nuclear que cubre las proximas decadas. Se sabe con bastante certeza que tipos de reactores se construiran y el tipo de combustible que se empleara en ellos en un principio, pero estos conocimientos son

  8. Effect of cobalt-60 {gamma} radiation and of thermal neutrons on high resistance P and N silicon. Possibility of obtaining a nuclear compensation for P type silicon; Effects du rayonnement {gamma} du cobalt 60 et de neutrons thermiques sur du silicium P et N de haute resistivite. Possibilite de realiser une compensation nucleaire d'un silicium du type P

    Energy Technology Data Exchange (ETDEWEB)

    Messier, J [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1965-11-01

    Type P silicon has been compensated by the production of a controlled and uniform amount of donor atoms ({sup 31}P) using thermal neutrons to bring about a nuclear transformation. It is shown that it is possible in this way to reduce by a factor of about one hundred the overall concentration of residual ionised impurities in the purest crystals obtained by floating zone purification (2 x 10{sup 12} atoms/cm{sup 3}). The degree compensation obtained is limited by the initial inhomogeneity of acceptor impurities which have to be compensated. Lattice defects which still remain after prolonged annealings reduce the life-time of the material to about 10 {mu}s approximately. Particle detectors having thicknesses of 2 to 5 mm have been built by this process; they give good results, particularly at low temperatures. A study has also been made of the number and of the nature of lattice defects produced by thermal neutrons in high resistivity P and N type crystals. These defects have been compared to those produced by {gamma} rays from {sup 60}Co. A discussion is given of the validity of the Wertheim model concerning pronounced recombination at low temperatures (77 deg. K - 300 deg. K) of primary defect-interstitial pairs. The nature of the defects introducing energy levels into the lower half of the forbidden band has been studied. (author) [French] On a compense du silicium de type P en produisant, au moyen de neutrons thermiques, par transmutation nucleaire une quantite controlee et uniforme d'atomes donneurs ({sup 31}P). On montre qu'on peut ainsi reduire de cent fois environ la densite nette d'impuretes ionisees residuelles subsistant dans les cristaux les plus purs obtenus par purification par zone flottante (2.10{sup 12} atomes/cm{sup 3}). Le degre de compensation obtenu est limite par i'inhomogeneite initiale des impuretes acceptrices a compenser. Des defauts de reseau qui subsistent meme apres des recuits prolonges reduisent la duree de vie du materiau a 10 {mu

  9. Problems related with the power regulation of reactors by physico-chemical methods, and the behaviour of water and heavy water in nuclear reactors; Comportement de l'eau et de l'eau lourde dans les reacteurs nucleaires et problemes de la regulation de puissance par voie physico-chimique

    Energy Technology Data Exchange (ETDEWEB)

    Dolle, L; Conan, D; Dirian, G [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-07-01

    Experience of the CEA heavy water reactors and a systematic study of the radiolytic decomposition of water in the core of swimming-pool reactors are described. Setting up of reactivity control by physico-chemical methods. Reactivity control by homogeneous poisoning of the reactor A comparison of the evolution of xenon poisoning with the residual anti reactivity of the poison in solution during its nuclear consumption establishes the programme which must govern the variation in its concentration if the exact compensation is to be produced The behaviour of the poison towards the reactor materials under the particular operational conditions must be taken into account. Radiolytic decomposition of water in the reactors in the presence of soluble poisons: A study of the effect of certain chemically inert salts, present in small concentrations in the water, on its radiolytic decomposition rate, has led to some new results which are discussed. The choice of a soluble poison is justified on the basis of the above results. Reactivity control by the use of a gaseous absorbent The use of a gas control rod circuit for compensation purposes, in place of solid control rods is described. The use of soluble poisons in the moderator to compensate the xenon effect, and of a gaseous absorbent in a circuit known as a gas control rod form original aspects of the reactivity control in the reactor EL 4. (authors) [French] L'observation du comportement de l'eau et de l'eau lourde dans les reacteurs en exploitation, contribue au fonctionnement sur de ceux-ci et oriente certaines etudes relatives aux techniques de controle de la reactivite par mise en oeuvre de poisons solubles. L'utilisation de poisons nucleaires dissous dans l'eau du reacteur entraine une pollution chimique de celle-ci. Les conditions d'emploi permettant d'eviter les effets indesirables de cette pollution sont etudiees. Les problemes analytiques - bien qu'importants - ne sont pas abordes dans le cadre de la communication

  10. Limits to the Recognizability of Flaws in Non-Destructive Testing Steam-Generator Tubes for Nuclear-Power Plants; Limitations de l'Efficacite de la Detection des Defauts par Essais Non Destructifs de Tubes de Bouilleurs pour Centrales Nucleaires; Predely ehffektivnosti nedestruktivnoj defektoskopii trub parogeneratorov yadernykh ehlektrostantsij; Limites para Distinguir los Defectos en el Ensayo No Destructivo de Tubo para Generadores de Vapor Destinados a Centrales Nucleares

    Energy Technology Data Exchange (ETDEWEB)

    Kuhlmann, A.; Adamsky, F. -J. [Technischer Ueberwachungs-Verein Reinland e.V., Cologne (Germany)

    1965-10-15

    In the Federal Republic of Germany there are nuclear reactors under construction with steam generators inside the reactor pressure-vessel. As a result design repairs of steam- generator tubes are very difficult and cause large shut-down times of the nuclear-power plant. It is known that numerous troubles in operating conventional power plants are results of steam-generator tube damages. Because of the high total costs of these reactors it. is necessary to construct the steam generators especially in such a manner that the load factor of the power plant is as high as possible. The Technischer Ueberwachungs-Verein Rheinland was charged to supervise and to test fabrication and construction of the steam generators to see that this part of the plant was as free of defects as possible. The experience gained during this work is of interest for manufacture and construction of steam generators for nuclear-power plants in general. This paper deals with the efficiency limits of non-destructive testing steam-generator tubes. The following tests performed will be discussed in detail: (a) Automatic ultrasonic testing of the straight tubes in the production facility; (b) Combined ultrasonic and radiographic testing of the bent tubes and tube weldings; (c) Other non-destructive tests. (author) [French] En Allemagne, on construit actuellement des generatrices nucleaires dans lesquelles les bouilleurs sont installes a l'interieur du caisson etanche du reacteur. Il s'ensuit que les reparations des tubes des bouilleurs sont tres difficiles et provoquent de longs arrets des centrales nucleaires. On sait que de nombreuses perturbations du fonctionnement des centrales classiques sont dues a des dommages dans les tubes des bouilleurs. C'est en grande partie en raison du prix de revient eleve de ces reacteurs qu'il est necessaire de construire les bouilleurs notamment de sorte que le facteur d'utilisation de la centrale soit aussi eleve que possible. C'est le ' Technischer Ueberwachungs

  11. Le Tumulus - Cromlech de Zaho II. (Compte rendu de fouille 1983. Autorisation n.º 001546 programmée H 23.

    Directory of Open Access Journals (Sweden)

    Jacques Blot

    1986-01-01

    Full Text Available La excavación de Zaho II, efectuada en Agosto de 1983, nos dió la oportunidad de encontrarnos frente a un tipo de monumento, que hasta entonces no había sido prácticamente estudiado. Este monumento de 9 metros de diámetro, presentaba una corona exterior formada de dos bases de piedras, una muy visible, una corona intermedia también de dos bases, no visibles antes de la excavación, y una cista central con carbón vegetal. Se encontró una punta de lanza del tipo Hallstatt final (R. Coquerel y la datación del carbón vegetal encontrado, indica: 2640 ± 90 o sea 690 ± 90 BC. La arquitectura, el ajuar y la datación concuerdan con el conjunto de otros monumentos fechados también en el último milenio antes de Cristo.

  12. Authorization Decree Application for the creation of the Flamanville-3 Basic Nuclear Installation. Executive Summary of the Technical Review

    International Nuclear Information System (INIS)

    2009-01-01

    On 9 May 2006, Electricite de France (EDF) submitted to the Ministers for Nuclear Safety an authorization decree application for an EPR-type reactor on the site of the Flamanville Nuclear Power Plant (NPP). Article 29 of Act No. 2006-686 of 13 June 2006 on Transparency and Security in the Nuclear Field prescribes that the creation of any basic nuclear installation shall be issued by a decree taken after consultation with the Nuclear Safety Authority (Autorite de surete nucleaire - ASN). The purpose of this report is to provide ASN's Board with a summary of the technical review led by ASN services and carried out by their technical support agencies, namely the IRSN, the GPR and the Standing Nuclear Section of the CCAP between 2001 and 2006. After summing up the conclusions of the review on the safety options of the European Pressurized Reactor (EPR) Project, as carried out between 1993 and 2000, this report describes the process and modalities of the review conducted from 2001 to 2006. Besides providing the opinion of ASN's services on the creation-licence application, it also outlines the further review to be carried out, if the authorization decree is issued. (authors)

  13. Nuclear geophysics in prospecting for ore and coal deposits; Geophysique nucleaire et prospection des gisements de charbon et autres mineraux; Yadernaya geofizika pri razvedke rudnykh i ugol'nykh mestorozhdenij; Geofisica nuclear u prospeccion de yacimientos de carbon y otros minerales

    Energy Technology Data Exchange (ETDEWEB)

    Bulashevich, Yu P; Voskobojnikov, G M; Muzyukin, L V

    1962-01-15

    eliminated by inverse probes. These neutron methods, and similarly neutron-activation logging, have also been applied at deposits of copper, manganese, aluminium and various other ores. Continuous-activation logging is appropriate where the occurring radioisotope has a suitable half-life. It is then possible to determine the optimum logging conditions (rate, length of probe, etc.) theoretically. Neutron recording during photo-neutron logging makes it possible to distinguish ore bodies containing beryllium, and to estimate the beryllium content from 0.001% upwards. Experience is confirming the effectiveness and economic expediency of nuclear geophysical methods in prospecting for ore and coal deposits. (author) [French] Les methodes de geophysique nucleaire s'emploient surtout pour l'exploration des gisements de charbon et autres mineraux par radiosondage. Dans le cas des gisements de charbon et d'autres mineraux de l'Union sovietique, les types suivants de prospection par sondage radioactif ou nucleaire (SR) trouvent une large application pratique : determination de la densite ou sondage gamma-gamma (S.G.G.) avec le {sup 60}cO comme source de rayonnements, sondage gamma-gamma selectif (S.G.G.S.) avec une source de rayonnements mous du type {sup 75}Se, sondage neutronsneutrons (S.N.N.) et sondage gamma-neutrons (S.G.N.) avec une source de neutrons Po-Be, sondage par activation - surtout par activation continue - avec emploi de la meme source, et sondage photo-neutronique avec l'emetteur gamma {sup 124}Sb. L'objet essentiel du S.R., dans les gisements de minerais, est de reconnaitre les differentes couches de minerais que l'on rencontre dans le trou de sonde, ce qui reduit le temps d'analyse, ainsi que d'evaluer approximativement, sur place, la teneur en elements utiles. Dans les gisements de charbon, le S.R. permet de determiner la profondeur, l'importance et la structure des veines. Les methodes dites S.G.G. et S.G.G.S. sont fondees sur l'enregistrement du rayonnement gamma

  14. An Appraisal of Analytical Methods for Plutonium and their Applications to the Analysis of Nuclear Materials; Evaluation des Methodes Analytiques de Dosage du Plutonium et de Leur Application a l'Analyse des Matieres Nucleaires; Otsenka analiticheskikh metodov opredeleniya plutoniya i ikh primenenie dlya analiza yadernykh materialov; Metodos Analiticos de Determinacion del Plutonio y su Empleo en el Analisis de Materiales Nucleares

    Energy Technology Data Exchange (ETDEWEB)

    Milner, G. W.C.; Phillips, G. [Atomic Energy Research Establishment, Harwell, Berks. (United Kingdom)

    1966-02-15

    programmes for new nuclear fuels. (author) [French] Il existe plusieurs methodes de dosage de la teneur en plutonium des matieres nucleaires. Pour les quantites de l'ordre du milligramme, les methodes utilisables sont la spectro- photometiie differentielle fondee sur la couleur de Pu (III), la gravimetrie fondee sur PuO{sub 2}, le comptage gamma et les methodes de reduction/oxydation comprenant les titrages poientiometriques et amperemetriques et la coulombmetrie a potentiel constant. Pour les quantites de Tordre du microgramme, le comptage alpha, la dilution isotopique et les methodes polarigraphiques sont a utiliser. Certaines methodes conviennent mieux que d'autres a des types determines d'echantillons et l'analyste soucieux d'obtenir les meilleurs resultats se heurte a un choix difficile. Les auteurs exposent les avantages et les inconvenients des methodes citees tels qu'ils se sont degages de l'experience acquise au cours des annees a l'Atomic Energy Research Establishment, et ils discutent l'exactitude, la precision, la sensibilite de ces methodes, et d'autres caracteristiques presentant un interet particulier. Certaines methodes ne peuvent etre utilisees si l'on n'a, dans une certaine mesure, separe le plutonium des autres constituants de l'echantillon et le memoire commente l'experience acquise avec l'echange d'anions et les procedes de chromatographie a phase inversee utilises a cette fin, en insistant surtout sur la mesure dans laquelle cette methode convient aux echantillons radioactifs. Les auteurs etudient en outre les nombreux problemes qui se sont poses lors de l'application (d'ailleurs couronnee de succes) de ces methodes a l'analyse des alliages de plutonium, des ceramiques et des cermets dans differentes combinaisons contenant de l'uranium, du thorium, du fer, du chrome, du molybdene, du cerium et du cobalt. Us exposent les difficultes de la dissolution des echantillons et de la reduction du plutonium a l'etat de valence voulu, ainsi que les avantages

  15. Nuclear Materials Management in a Recovery Facility for Unirradiated Enriched Uranium; Gestion des Matieres Nucleaires dans une Installation de Recuperation d'Uranium Enrichi Non Irradie; Administrativno-khozyajstvennyj uchet yadernykh materialov na ustanovke po regeneratsii neobluchennogo obogashchennogo urana; Administracion de Materiales Nucleares en una Planta de Recuperacion para Uranio Enriquecido No Irradiado

    Energy Technology Data Exchange (ETDEWEB)

    Jasny, G. R. [Union Carbide Corporation, Oak Ridge, TN (United States)

    1966-02-15

    poussee du personnel charge des operations. Le transfert des informations au service de comptabilite des matieres nucleaires est assure au moyen d'un systeme de fiches qui accompagnent les matieres: chaque lot est identifie par une fiche individuelle et la livraison du lot est signalee par transfert de la fiche au service de comptabilite des matieres nucleaires{sup .} La plupart des operations comptables sont executees sur des appareils electroniques de traitement de l'information; outre les dossiers et calculs necessaires pour l'etablissement des bilans matieres, on enregistre regulierement des donnees sur la retention et la concentration afin de faciliter la detection des anomalies dans les bilans entree/sortie ou dans les inventaires. L'analyse statistique est largement utilisee pour verifier les mesures et reduire au minimum le nombre d'analyses chimiques. Toutefois, l'application des statistiques n'a pas donne de bons resultats pour l'evaluation des erreurs d'inventaire. Le memoire etudie de maniere detaillee les methodes de controle des matieres indiquees plus haut et certains des problemesiqu'elles posent. (author) [Spanish] Desde hace mas de veinte anos, la planta Y-12 de la Comision de Energia Atomica, situada en Oak Ridge, Tennessee, viene tratando y recuperando diversas formas de uranio enriquecido no irradiado. El proceso de recuperacion consiste en un tren semicontinuo de operaciones unitarias: disolucion, combustion, evaporacion, extraccion, desnitrificacion e hidrofluoracion. El equipo de tratamiento y almacena - miento es de dimensiones restringidas para evitar la criticidad y tiene una capacidad combinada de varios centenares de kg de uranio enriquecido al mes. El material sometido a las operaciones de recuperacion proviene tanto de la planta como de otras instalaciones que la CEA posee en los Estados Unidos. Este material incluye practicamente todos los tipos de residuos de uranio enriquecido sin irradiar. El control fisico se ejerce satisfactoriamente

  16. Use of semiconductors in lieu of emulsions in nuclear spectroscopy; Utilisation de semi-conducteurs a la place d'emulsions en spectroscopie nucleaire; Primenenie poluprovodnikov vmesto ehmul'sij v yadernoj spektroskopii; Sustitucion de las emulsiones por semiconductores en espectroscopia nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Bilaniuk, O M; Marsh, B B [University of Rochester, Rochester, NY (United States)

    1962-04-15

    field present and with the cyclotron in full operation. Complete circuitry of the decoding scheme is presented and samples of nuclear data collected with the unit are shown. (author) [French] Dans un spectrometre magnetique a fort pouvoir de resolution, on remplace l'emulsion nucleaire par vingt compteurs a barriere de surface obtenus par evaporation d'or sur du germanium de type n, ou par vingt compteurs a jonction obtenus par diffusion de phosphore dans du silicium de type p. Pour eviter d'avoir a utiliser des amplificateurs et des enregistreurs distincts pour chaque cristal, on connecte les sorties des divers compteurs a une ligne a retard a constantes localisees, ce qui permet de supprimer les condensateurs alternes de la ligne. Quand une particule ionisante frappe un compteur, l'impulsion qui en resulte se dirige vers les deux extremites de la ligne a retard. Chacune des vingt cellules de la ligne se compose de deux inductances de 35 {mu}H et de deux condensateurs de 60 pF dont l'un est le compteur lui-meme et ses connexions. Chaque cellule assure un retard de t = 2(LC){sup 1/2}2 = 90 ns. Ainsi l'intervalle de temps entre les impulsions qui arrivent aux extremites de la ligne a retard differera de 180 ns pour deux detecteurs adjacents. Les deux extremites de la ligne a retard sont connectees respectivement a un amplificateur de depart et a un amplificateur d'arrivee, suivis de circuits de mise en forme et de circuits de declenchement identiques. Leurs signaux de sortie agissent sur un convertisseur 6BN6 tempsamplitude. Un retard fixe d'avance de 2,5 {mu}s est prevu dans l'amplificateur d'arrivee, si bien que l'impulsion d'arrivee atteint toujours le convertisseur temps-amplitude apres l'impulsion de depart. L'amplitude de l'impulsion sortant du convertisseur 6BN6 est proportionnelle a l'intervalle de temps entre les impulsions de depart et d'arrivee. Ainsi les signaux provenant des divers compteurs de l'ensemble sont decodes en hauteurs d'impulsion. Les differentes

  17. Movies about nuclear disasters; Le nucleaire fait son cinema

    Energy Technology Data Exchange (ETDEWEB)

    Portelli, A.; Guarnieri, F.; Martin, C. [Centre de recherche sur les Risques et les Crises - CRC, Mines ParisTech, Paris (France)

    2014-01-15

    'The China Syndrome' by J.Bridges is the most famous film about nuclear energy, it was released in 1979 and tells the story of a television reporter who discovers safety cover-ups in the Ventana nuclear power plant. In the film 'Mount Fuji in red' a part of 'Akira Kurosawa's dreams' film released in 1990, the eruption of the Mount Fuji triggered a series of accidents in Japanese nuclear plants which sent millions of people fleeing in terror and blocked by the ocean. More recent films are 'Land of Oblivion' by M.Boganim - 2012, 'The land of hope' by S.Sion - 2012 or 'Grand Central' by R. Zlotowski - 2013. All this list of films depicting nuclear disasters and their dramatic consequences on the daily life of people contribute to build a frightening picture of nuclear energy in the mind of people. Although any film is fictional it can influence people but also open people's eyes on society issues like sub-contracting, unemployment, risk assessment... (A.C.)

  18. Overview of the Russian nuclear industry; Le panorama nucleaire russe

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-02-15

    In 2004, President Poutine decided to replace the atomic energy ministry (Minatom) by the federal atomic energy agency (Rosatom). Several projects were launched during the next two years which aimed at bringing back Russia to the fore front of the world leaders of nuclear energy use and nuclear technology export. In 2007, Rosatom agency was changed to a public holding company and a new company, named Atomenergoprom, was created which gathers all civil nuclear companies (AtomEnergoMash for the exploitation of power plants, Technabsexport (Tenex) specialized in enrichment or Atomstryexport in charge of export activities). Thus, Rosatom is at the head of all civilian and military nuclear companies, of all research centers, and of all nuclear and radiological safety facilities. In 2006, Russian nuclear power plants supplied 15.8% of the whole power consumption. Russia wishes to develop its nuclear program with the construction of new reactors in order to reach a nuclear electricity share of 25% from now to 2020. This paper presents first the 2007 institutional reform of the Russian atomic sector, and the three sectorial federal programmes: 1 - development of the nuclear energy industrial complex for the 2007-2010 era and up to 2015 (future power plants, nuclear fuel centers and reactor prototypes), 2 - nuclear safety and radioprotection for the 2008-2015 era (waste management, remedial actions, radiation protection), 3 - military program (confidential). Then, the paper presents: the international actions (export of Russian technology, cooperation agreements, non-proliferation), the situation of the existing nuclear park (reactors in operation, stopped, under construction and in project), the fuel cycle activities (production of natural uranium, enrichment, fuel fabrication, spent fuel storage, reprocessing, waste management), the nuclear R and D in Russia, and the nuclear safety authority. (J.S.)

  19. The nuclear situation in India; La situation nucleaire en Inde

    Energy Technology Data Exchange (ETDEWEB)

    Macias, R.M

    2006-07-01

    This report first recalls that India lacks of energy natural resources, faces a high demographic growth and high electricity demand, and launched a civil nuclear program in the 1960's which comprises three stages: a first one with natural uranium fuelled PHWR type reactors, a second one with fast neutron reactors (which is now at its beginning), and a third one which will use the thorium-uranium 233 cycle both in fast neutron and AHWR (advanced heavy water reactor)type reactors. After the indication of some data on the present and foreseen nuclear capacity, this report presents the authorities and actors of the nuclear sector, the national laws related to nuclear activities, the Indian position with respect to international treaties and conventions, indicates the location of the numerous nuclear installations, gives some characteristics of the existing and projected nuclear power stations and research reactors. It presents the fuel manufacturing and reprocessing activities, the sites of heavy water production and their capacities. It gives an overview of the waste management activity (origin, classification, processing and packaging for the different types of wastes, warehousing and storage with different technologies and technical options depending on the waste type)

  20. US nuclear survey; Le panorama nucleaire aux Etats-Unis

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-08-01

    This document gives a broad overview of the organization of nuclear activities in the USA: nuclear park and availability (reactors, R and D), fuel cycle (uranium enrichment, wastes management (storage and disposal sites)). (J.S.)

  1. Nuclear, phantasm and emotions; Nucleaire, fantasmes et emotions

    Energy Technology Data Exchange (ETDEWEB)

    Michel, A

    2009-03-15

    Nuclear energy as it appears in novels and films gives an image that can influence our judgment. If the phantasms amplified by the antinuclear groups can influence the public opinion, so the communication on the nuclear subjects must be more emotional to touch the general public. Through different images carried in comic books or in fiction novels it is the anxiety that is privileged. If nuclear industry must propose a rational and well informed approach that gives value to its experience, this must not prevent to consider a more emotional perspective. (N.C.)

  2. A comprehensive survey of nuclear reactions; Panorama des reactions nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Cugnon, J. [Liege Univ., IFPA, AGO Dept. (Belgium)

    2007-07-01

    The various mechanisms of nuclear reactions are surveyed and classified in different regimes, based on the notions of coherent mechanisms and hard versus soft processes. The emphasis is put on the concepts at the basis of the understanding of these regimes and on the elements of nuclear structure which are involved in these different regimes, as well as the on the possibility of extracting this information. Due to lack of space and for pedagogical reasons, the discussion is limited to nucleon-induced and light-ion-induced reactions. However, a few remarks are given concerning some specific probes, such as weakly bound projectiles or neutron-rich nuclei. (author)

  3. Nuclear: how to get off?; Nucleaire: comment en sortir?

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    This study aims to propose actions to get off the nuclear in less than 10 years. The first part is devoted to the energy efficiency: the energy produced by the today electric network, the energy conservation in the ternary, industrial and residential sector. The second part presents an offer of electricity without the nuclear: the renewable energies, the fossil energies, the carbon tax and the nuclear park closure. (A.L.B.)

  4. New reactor concepts; Nieuwe rectorconcepten - nouveaux reacteurs nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Meskens, G.; Govaerts, P.; Baugnet, J.-M.; Delbrassine, A

    1998-11-01

    The document gives a summary of new nuclear reactor concepts from a technological point of view. Belgium supports the development of the European Pressurized-Water Reactor, which is an evolutionary concept based on the European experience in Pressurized-Water Reactors. A reorientation of the Belgian choice for this evolutionary concept may be required in case that a decision is taken to burn plutonium, when the need for flexible nuclear power plants arises or when new reactor concepts can demonstrate proved benefits in terms of safety and cost.

  5. All about nuclear sciences; Tout savoir sur le nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Le Blanc, A. [CEA Saclay DSM-SAC/USL2TI/STI/SVI, 91 - Gif-sur-Yvette (France)

    2009-07-01

    This French/English flyer, made by the French INIS team of CEA-Saclay, presents the INIS information system, the coverage and content of the database and makes the promotion of the opening of the database to free access through the web link: http://inisdb2.iaea.org/. (J.S.)

  6. The repertory set of nuclear energy; Le repertoire du nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-05-15

    This second documentary form, edited by the national association of local commissions of information about nuclear activities (ANCLI), is a glossary of the main terms used in the nuclear industry domain. (J.S.)

  7. EPR: the nuclear impasse; EPR: l'impasse nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Marillier, F [Association Ecologiste Greenpeace (France)

    2008-07-01

    The questions relative to the climatic change constitute crucial challenges for the next ten years. In this context the author aims to show how the EPR project illustrates the nuclear french ''autism''. He presents and analyzes the international and environmental impacts of this obsolete technology, as a project useless and dangerous. (A.L.B.)

  8. Bescherming tegen de gevolgen van de nucleaire elektromagnetische impuls

    NARCIS (Netherlands)

    Möhring, F.; Sevat, P.A.A.

    1972-01-01

    Protection against the effects of the nuclear electromagnetic pulse. A nuclear explosion generates a short impulsive electromagnetic field which propagates over the earth radially from the point of explosion. In the explosion zone the electric and magnetic fieldstrengths are high and may damage

  9. Energy: nuclear energy; Energies: l'energie nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Lung, M. [Societe Generale pour les Techniques Nouvelles (SGN), 78 - Saint-Quentin-en-Yvelines (France)

    2000-11-01

    Convinced that the nuclear energy will be the cleaner, safer, more economical and more respectful of the environment energy of the future, the author preconizes to study the way it can be implemented, to continue to improve its production, to understand its virtues and to better inform the public. He develops this opinion in the presentation of the principal characteristics of the nuclear energy: technology, radioactive wastes, radiation protection, the plutonium, the nuclear accidents, the proliferation risks, the economics and nuclear energy and competitiveness, development and sustainability. (A.L.B.)

  10. INIS, CEA and nuclear terminology; INIS, CEA et terminologie nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Surmont, J.; Brulet, C.; Constant, A.; Guille, N.; Le Blanc, A.; Mouffron, O.; Anguise, P.; Jouve, J.J

    2007-07-01

    This poster, prepared for the fifth edition of the meetings of scientific and technical information professionals (RPIST, Nancy (France)), presents, first, the INIS information system, its content and coverage, the French participation to this system and the role of the CEA-Saclay as France's official representative for this system. Then it presents the INIS thesaurus with its different levels as a terminological tool for the indexing of documents and for searching documents inside the database. Finally, the very first electronic version of the multilingual thesaurus is introduced. Several national INIS centres, including the CEA-Saclay, have contributed to the translation of lists of new terms and of forbidden terms (synonyms). (J.S.)

  11. Non-nuclear energies; Les energies autres que le nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Nifenecker, H. [Laboratoire de Physique Subatomique et de Cosmologie, IN2P3-CNRS/UJF/INPG, 53 av. des Martyrs, 38026 Grenoble Cedex and Sauvons le Climat (http://www.sauvonsleclimat.org), Grenoble (France)

    2007-07-01

    The different meanings of the word 'energy', as understood by economists, are reviewed and explained. Present rates of consumption of fossil and nuclear fuels are given as well as corresponding reserves and resources. The time left before exhaustion of these reserves is calculated for different energy consumption scenarios. On finds that coal and nuclear only allow to reach the end of this century. Without specific dispositions, the predicted massive use of coal is not compatible with any admissible value of global heating. Thus, we discuss the clean coal techniques, including carbon dioxide capture and storage. One proceeds with the discussion of availability and feasibility of renewable energies, with special attention to electricity production. One distinguishes controllable renewable energies from those which are intermittent. Among the first we find hydroelectricity, biomass, and geothermal and among the second, wind and solar. At world level, hydroelectricity will, most probably, remain the main renewable contributor to electricity production. Photovoltaic is extremely promising for providing villages remote deprived from access to a centralized network. Biomass should be an important source of bio-fuels. Geothermal energy should be an interesting source of low temperature heat. Development of wind energy will be inhibited by the lack of cheap and massive electricity storage; its contribution should not exceed 10% of electricity production. Its present development is totally dependent upon massive public support. A large part of this paper follows chapters of the monograph 'L'energie de demain: technique, environnement, economie', EDP Sciences, 2005. (author)

  12. Nuclear waste management; La gestion des dechets nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Nifenecker, H.

    2008-07-01

    The author gives an overview of the main issues related to the use of nuclear energy: the management and the environmental impact of wastes. After having outlined the different radiological consequences of different radionuclides, he proposes an approximate assessment of waste production which may depend on reactor technology, and which needs a distinction between low level, intermediate level, and high level wastes. He discusses the differences between primary energies and final energies, and how to consider nuclear energy and its wastes within this classification. Then, considering the deep geological storage, he describes how contamination may occur and the risks for the population as well as for the environment. After having evoked the use of breeder reactors and its separation-transmutation issues, the author briefly comments the nuclear waste financing issue

  13. Liability for the nuclear risk; Aansprakelijkheid voor het nucleaire risico

    Energy Technology Data Exchange (ETDEWEB)

    Faure, M. [ed.] [Rijksuniversiteit Limburg, Maastricht (Netherlands); Govaerts, P.; Malbrain, C.; Veuchelen, L. [Centre d`Etude de l`Energie Nucleaire, Mol (Belgium); Spriet, B. [Katholieke Univ. Leuven (Belgium). Inst. voor Strafrecht; Heldeweg, M.; Hertogs, M.; Van Maanen, G.; De Roos, T.; Seerden, R. [Maastrichts Europees Instituut voor Transnationaal Rechtswetenschappelijk Onderzoek METRO, Rijksuniversiteit Limburg, Maastricht (Netherlands)

    1993-12-31

    Results of a cooperative research project on the juridical aspects of nuclear risk (criminal, civil and administrative aspects), according to the Belgian and Dutch laws, are presented. In this multi-disciplinary project also attention is paid to the economic impacts and positive-scientific aspects of the nuclear risk regarding radioactive waste problems and nuclear accidents. The liability for and the decision-making regarding the site selection of nuclear power plants is dealt with as well. 9 figs., 23 tabs., 198 refs.

  14. Nuclear disarmament: the rebound?; Desarmement nucleaire: le rebond?

    Energy Technology Data Exchange (ETDEWEB)

    Durand, D. [Institut de Documentation et de Recherche sur la Paix - I. D. R. P., 93 - Saint-Ouen (France)

    2010-07-01

    The elimination of nuclear weapons is very often considered as a naive and unrealistic utopia, or as an ethical ambition or requirement but with no possible implementation. In this book, the author shades light on some concrete elements of the existing debate between international actors: governments, institutions, but also non-governmental organizations and opinion movements born during the last non-proliferation treaty conference. (J.S.)

  15. Nuclear power in our societies; Le nucleaire dans nos societes

    Energy Technology Data Exchange (ETDEWEB)

    Fardeau, J.C.

    2011-07-01

    Hiroshima, Chernobyl, Fukushima Daiichi are the well known sad milestones on the path toward a broad development of nuclear energy. They are so well known that they have blurred certainly for long in a very unfair way the positive image of nuclear energy in the public eye. The impact of the media appetite for disasters favours the fear and puts aside all the achievements of nuclear sciences like nuclear medicine for instance and all the assets of nuclear power like the quasi absence of greenhouse gas emission or its massive capacity to produce electricity or heat. The unique solution to enhance nuclear acceptance is the reduction of the fear through a better understanding of nuclear sciences by the public. (A.C.)

  16. EPR: the nuclear impasse; EPR: l'impasse nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Marillier, F. [Association Ecologiste Greenpeace (France)

    2008-07-01

    The questions relative to the climatic change constitute crucial challenges for the next ten years. In this context the author aims to show how the EPR project illustrates the nuclear french ''autism''. He presents and analyzes the international and environmental impacts of this obsolete technology, as a project useless and dangerous. (A.L.B.)

  17. Nuclear law; Le droit nucleaire 2006-2008

    Energy Technology Data Exchange (ETDEWEB)

    Bringuier, P. [Montpellier-1 Univ., Droit International Public, UMR 5815, 34 (France)

    2009-10-15

    The object of this report is to present the evolution of the nuclear law during the period from 2006 to 2008, period that was characterized in France by a real rewriting from the implementation of a control authority. The prescriptive backing of nuclear activities has been deeply changed by numerous texts. In this first part are presented: (1) the institutional aspects, (2) openness and public information, (7) radioactive wastes and (9) liability and insurance. In a next publication will be treated: (3) safety and radiation protection; (4) nuclear matter, inspection, physical protection; (5) transports; (6) trade, non-proliferation; (8) radiological accidents. (N.C.)

  18. Nuclear safety in France: Extracts from 'Revue Generale Nucleaire'

    International Nuclear Information System (INIS)

    1979-07-01

    Translations of 3 articles are included in this report. The first covers briefly the tasks and organisation of the Institute of Nuclear Protection and Safety (IPSN) in France. In the second article the principles of cost effectiveness are described and the applications of the general methodology to radiation protection is outlined. A study by the US Environmental Protection Agency is summarised. Methods for risk estimation in nuclear energy are presented in the final article

  19. Give up the nuclear deterrence?; Renoncer a la dissuasion nucleaire?

    Energy Technology Data Exchange (ETDEWEB)

    Savoyant, L

    2009-07-15

    The nuclear deterrence question is always today the subject of a large consensus in spite of the evolution of its creation conditions. Taking into account the proliferation risk, the France could play a role in the disarmament process including the whole renouncement to the nuclear deterrence. (A.L.B.)

  20. The nuclear weapon; L'arme nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Tertrais, Bruno

    2008-07-01

    The author presents the technology, the concept of deterrence, the today means and the international control, concerning the nuclear weapon. The conclusion is pessimistic. The author sees only two issues: the substitution of a new weapon more powerful, or its use. (A.L.B.)

  1. French Senate debate on nuclear deterrence; Dissuasion nucleaire francaise

    Energy Technology Data Exchange (ETDEWEB)

    Vincon, S. [UMP Cher (France); Bentegeat, H. [Cema, 75 - Paris (France); Verwaerde, D. [CEA Bruyeres le Chatel, 91 (France); Quinlan, M. [IISS, Londre (United Kingdom); Tertrais, B. [Fondation pour la Recherche Strategique (FRS), 75 - Paris (France)

    2006-07-15

    The Senate committee on foreign affairs, defence and the Armed Forces met at a round table session on 14 June 2006 to discuss French nuclear deterrence. Serge Vincon presided the discussion, which covered three aspects of the subject: first, an analysis of the current and medium-term future strategic contexts and their consequences for the role of deterrence, and thus whether or not current doctrine is matched to current and future threats; second, the assets dedicated to deterrence, how well they reflect doctrine and how they fit in with other defence priorities; and finally an examination of Britain position within NATO along with future possibilities arising from closer European defence cooperation. (author)

  2. The nuclear deterrence in 2030; La dissuasion nucleaire en 2030

    Energy Technology Data Exchange (ETDEWEB)

    Tertrais, B. [Fondation pour la Recherche Strategique (FRS), 75 - Paris (France)

    2007-05-15

    This article presents the conclusions of the prospective analysis, of December 2006, on the future of the french nuclear deterrence after 2015, under the responsibility of the Foundation for the strategic research. The principal objective is to reflect on what the nuclear world might look like during the first part of the 21. century, beyond the modernization decisions already planned or envisaged and to draw conclusions for the future of the french deterrent. (A.L.B.)

  3. The nuclear Asia; L'Asie nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Cordonnier, I.; Tertrais, B

    2001-07-01

    Since the demolition of the Berlin wall, Asia has become the theater of nuclear rivalry, with as main actors: india, Pakistan, China and South Korea. This book analyzes the geo-political situation in this region of the world and asks some important questions about the new strategic map of Asia: what is the impact of the development of nuclear activities on the security of Asia? Will the deployment of anti-missile defenses lead to a new weapons rush? Is there a nuclear warfare risk? (J.S.)

  4. The nuclear fuel cycle; Le cycle du combustible nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-05-01

    After a short introduction about nuclear power in the world, fission physics and the French nuclear power plants, this brochure describes in a digest way the different steps of the nuclear fuel cycle: uranium prospecting, mining activity, processing of uranium ores and production of uranium concentrates (yellow cake), uranium chemistry (conversion of the yellow cake into uranium hexafluoride), fabrication of nuclear fuels, use of fuels, reprocessing of spent fuels (uranium, plutonium and fission products), recycling of energetic materials, and storage of radioactive wastes. (J.S.)

  5. Iran: what nuclear sanctuary?; Iran: quel sanctuaire nucleaire?

    Energy Technology Data Exchange (ETDEWEB)

    Viaud, P.

    2010-05-15

    The author continues his study of Iran and its implicit nuclear strategy by showing us the three circles of sanctuary that it contains. He shows to what extent this country, with its strong and ancient geopolitical identity, has managed to restore its rank at the centre of the geostrategic and geo-economic chessboard of the region. (author)

  6. What nuclear industry after Fukushima?; Quel nucleaire apres Fukushima?

    Energy Technology Data Exchange (ETDEWEB)

    Barre, Bertrand [Institut national des sciences et techniques nucleaires, CEA-Saclay, 91191 Gif-sur-Yvette Cedex (France)

    2011-07-01

    Nuclear power experienced a fast growth during the 70's and 80's, but a quasi-stagnation during the 90's. Since the beginning of the 21. century, a so-called renaissance could be witnessed, fuelled by concerns about energy security of supply, volatility of oil and gas prices, fear of an incoming 'peak oil', and, last but not least, the threat of global climate change due to the anthropogenic emissions of greenhouse effect gases. Then, on March 11 2011, a monster earthquake followed by a violent tsunami triggered an accident which all but destroyed four nuclear reactors on the Fukushima-Daiichi site, on the east coast of Honshu, the main Japanese island. There was meltdown in three reactor cores, hydrogen explosions which blew off the upper structures of four reactor buildings, and massive radioactive contamination of a spread of land north-west of the site as well as radioactive releases to the ocean. This accident triggered reactions of various intensities throughout the world, awakening the fears, and questions raised 25 years before by the Chernobyl accident. But the tsunami did not make the fundamentals of the renaissance disappear. After a pause, to fully learn lessons from the accident, the renaissance is likely to start again, all the much since the 'third generation' nuclear plants would have survived unscathed the Fukushima earthquake and tsunami. (author)

  7. Nuclear and sustainable development; Nucleaire et developpement durable

    Energy Technology Data Exchange (ETDEWEB)

    Audebert, P.; Balle, St.; Barandas, Ch.; Basse-Cathalinat, B.; Bellefontaine, E.; Bernard, H.; Bouhand, M.H.; Bourg, D.; Bourgoignon, F.; Bourlat, Y.; Brunet, F.; Buclet, N.; Buquet, N.; Caron, P.; Cartier, M.; Chagneau, E.; Charles, D.; Chateau, G.; Collette, P.; Collignon, A.; Comtesse, Ch.; Crammer, B.; Dasnias, J.; Decroix, G.; Defoy, B.; Delafontaine, E.; Delcroix, V.; Delerue, X.; Demet, M.; Dimmers, G.; Dodivers, S.; Dubigeon, O.; Eimer, M.; Fadin, H.; Foos, J.; Ganiage, D.; Garraud, J.; Girod, J.P.; Gourod, A.; Goussot, D.; Guignard, C.; Heloury, J.; Hondermarck, B.; Hurel, S.; Jeandron, C.; Josse, A.; Lagon, Ch.; Lalleron, Ch.; Laurent, M.; Legrand, H.; Leveau, E

    2006-07-01

    On September 15. and 16., 2004, at Rene Delcourt invitation, President of the C.L.I. of Paluel and Penly, took place the 4. colloquium of the A.N.C.L.I.. Jean Dasnias, new President of the C.L.I., welcomed the colloquium. Hundred of persons participated. The place of the nuclear power in the energy perspectives of tomorrow, its assets and its weaknesses in front of the other energies and within the framework of a sustainable development, are so many subjects which were discussed. The different tackled subjects are: the stakes in the sustainable development; energy perspectives; the reactors of the fourth generation; nuclear power and transparency; sustainable development and I.R.S.N. (N.C.)

  8. Nuclear armament and disarmament; Armement et desarmement nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-05-01

    This document discusses the objectives and the specifications of the non-proliferation treaty, in the framework of the nuclear armament and disarmament. Three chapters are proposed: State of the art; the international agreements and treaties and the United Nation Organization part; debates and forecasts on the proliferation fight, the Pugwash movement and a chronology of the situation. (A.L.B.)

  9. experience du service de medecine nucleaire sahloul sousse dans ...

    African Journals Online (AJOL)

    tics of the tumor and the Tg values of. Conclusion: The ablative efficiency is optimized by 131 cures iodine should be extended until the Tg remains high. Monitoring life is necessary and the thresholds Tg below 2ng/ml is required. Keywords: Differentiated thyroid Cancers, Thyroglobulin, Iodine 131, Prediction, Monitoring.

  10. The 9. European nuclear conference; La 9. conference nucleaire europeenne

    Energy Technology Data Exchange (ETDEWEB)

    Maurel, V.; Lewis, D.; Smirnov, V.P.; Gutierrez, J.E.; Paulin, Ph.; Markov, D.V.; Smirnov, A.V.; Polenok, V.S.; Horhoianu, G.; Olteanu, G.; Van der Schaaf, B.; Gavillet, D.; Lapena, J.; Ohms, C.; Roth, A.; Van Dyck, St.; Mardon, J.P.; Thomas, A.; Cipiere, M.F.; Faidy, C.; Hedin, F.; Delnondedieu, M.; Chassignole, B.; Doudet, L.; Dupond, O.; Kang, K.; Park, K.; Kim, K.; Ha, J.; Hoon-Seok, Jung; Yong-koo, Lee; Kwang-Ho, Kim; Seungwoo, Paek; Heui-Joo, Choi; Do-Hee, Ahn; Kwang-Rag, Kim; Minsoo, Lee; Sung-Paal, Yim; Hongsuk, Chung; Detroux, P.; Meessen, O.; Defloor, J.; Lars-Erik, Holm; Barescut, J.C.; Vacquier, B.; Laurier, D.; Caer, S.; Quesne, B.; Oudalova, A.; Geras' kin, St.; Dikarev, V.; Dikareva, N.; Chernonog, E.; Yang-Geun, Chung; Gab-Bock, Lee; Sun-Young, Bang; Yong-Sun, Lee; Bolognese-Milsztajn, T.; Frank, D.; Lacoste, V.; Pihet, P.; Lacronique, J.F.; Chauliac, C.; Verwaerde, D.; Pavageau, O.; Zaetta, A.; Varaine, F.; Warin, D.; Hudelot, J.P.; Bioux, Ph.; Klann, R.; Petruzzi, A.; D' auria, F.; Yung Kwon, Jin; Chul Jin, Chol; Mihalache, M.; Radu, V.; Pavelescu, M.; Schneidesch, Ch.R.; Jinzhao, Zhang; Dalleur, J.P.; Nuttin, A.; Meplan, O.; Wilson, J.; Perdu, F.; Campioni, G.; Mounier, C.; Sigrist, J.F.; Laine, Ch.; Broc, D.; Robbe, M.F.; Cariou, Y.; Seok-Kyun, Yoon; Win, Naing; Myung-Hyun, Kim; Kyung, Hee; Fridman, E.; Shwageraus, E.; Galperin, A.; Meplan, O.; Laulan, O.; Mechel-Sendis, F.; Belgaid, M.; Kadem, F.; Amokrane, A.; Hamidouche, T.; El-Khider, Si-Ahmed

    2005-11-15

    This issue gathers the abstracts of the papers presented at the ninth European nuclear conference (ENC-2005). The main part of the conference is split into 20 sessions. These sessions cover all technical aspects of nuclear power, from reactor design to waste management, without forgetting experimental and research reactors, reactor dismantling, economy, resources, safety, radioprotection and education issues. Perspectives of a nuclear renaissance are clearly visible in the world. This renaissance, mainly due to political, economical, societal and ecological factors, is fuelled by scientific and technical progress. This conference was the opportunity to present together these aspects of nuclear power and to analyze their mutual interactions.

  11. Nuclear molecular imaging of paragangliomas; Imagerie moleculaire nucleaire des paragangliomes

    Energy Technology Data Exchange (ETDEWEB)

    Taieb, D.; Tessonnier, L.; Mundler, O. [Service central de biophysique et de medecine nucleaire, CHU de la Timone, 13 - Marseille (France)

    2010-08-15

    Paragangliomas (PGL) are relatively rare neural crest tumors originating in the adrenal medulla (usually called pheochromocytoma), chemoreceptors (i.e., carotid and aortic bodies) or autonomic ganglia. These tumors are highly vascular, usually benign and slow-growing. PGL may occur as sporadic or familial entities, the latter mostly in association with germline mutations of the succinate dehydrogenase (SDH) B, SDHC, SDHD, SDH5, von Hippel-Lindau (VHL), ret proto-oncogene (RET), neurofibromatosis 1 (NF1) (von Recklinghausen's disease), prolyl hydroxylase domain protein 2 (PHD2) genes and TMEM127. Molecular nuclear imaging has a central role in characterization of PGL and include: somatostatin receptor imaging ({sup 111}In, {sup 68}Ga), MIBG scintigraphy ({sup 131}I, {sup 123}I), {sup 18}F-dihydroxy-phenylalanine ({sup 18}F-DOPA) positron emission tomography (PET), and {sup 18}F-deoxyglucose ({sup 18}F-FDG) PET. The choice of the tracer is not yet fully established but the work-up of familial forms often require the combination of multiple approaches. (authors)

  12. Nuclear engineering vocabulary; Vocabulaire de l'ingenierie nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    The terms, expressions and definitions presented in this booklet come from the works carried out by the French specialized commission of nuclear engineering terminology and neology. This selection of terms cannot be found, in general, in classical dictionaries, or can be found but with a different meaning than the one used in nuclear engineering. All terms and expressions contained in this booklet have been already published in different issues of the Official Journal of the French Republic. This publication makes their use mandatory in replacement of foreign language equivalents inside all government services and public buildings. (J.S.)

  13. Exit this way; Par ici la sortie du nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    This paper aims to inform the public on the nuclear power phaseout necessity. The fist part presents the hazards bound the nuclear activities, from the uranium mines to the radioactive wastes disposal and the reasons of a necessary phaseout. The second part recalls the historical aspects of the nuclear power implementation in the french energy policy and the today government attitude to value its choice. The last part presents the advantages of other energies sources and scenario of nuclear power phaseout. (A.L.B.)

  14. Perspectives for nuclear energy; Perspectives pour l'energie nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Baugnet, J -M; Abderrahim, H A; Dekeyser, J; Meskens, G

    1998-09-01

    In Belgium, approximately 60 percent of the produced electricity is generated by nuclear power. At present, nuclear power production tends to stagnate in Europe and North America but is still growing in Asia. The document gives an overview of the present status and the future energy demand with emphasis on electric power. Different evaluation criteria including factors hindering and factors promoting the expansion of nuclear power as well as requirements of new nuclear power plants are discussed. The extension of the lifetime of existing facilities as well as fuel supply are taken into consideration. A comparative assesment of nuclear power with other energy sources is made. The report concludes with estimating the contribution and the role of nuclear power in future energy demand as well as with an overview of future reactors and research and development programmes.

  15. The experimental nuclear reactor: AQUILON; Le reacteur nucleaire experimental: AQUILON

    Energy Technology Data Exchange (ETDEWEB)

    Girard, Y; Koechlin, J C; Moreau, J M [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    'Aquilon' is an experimental reactor specially designed for the neutronic study of heterogeneous multiplying media with solid fuel and liquid moderator. Since this study is in general incompatible with energy production, the power of the reactor has been limited to a minimum so as to be able to obtain a simple and compact structure, easy access, good handling and great flexibility of operation and utilisation. (author) [French] 'Aquilon' est un reacteur experimental specialement concu pour l'etude neutronique de milieux multiplicateurs heterogenes a combustible solide et ralentisseur liquide. Cette etude etant en general incompatible avec la production d'energie, on a limite au minimum la puissance du reacteur pour pouvoir obtenir une structure simple et peu encombrante, un acces facile, une bonne maniabilite et une grande souplesse de fonctionnement et d'utilisation. (auteur)

  16. The large nuclear works; Le grand chantier du nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Stephan, C. [Institut de Physique Nucleaire, (CNRS) 91 - Orsay (France)

    2010-10-15

    This article comments the present development of nuclear energy in the world. This energy is very attractive because it has no impact on greenhouse effect. The author briefly describes the various types of nuclear reactors, their operation principle, their power, their availability, their reliability, their reinforced safety. He also evokes the technological developments which lead to third generation reactors which are currently operated (the EPR is more particularly described). He comments the waste management issue, the possibility of fuel recycling, evokes the Myrrha reactor project, and the perspective of fourth generation reactors which will have to be both critical and sur-regenerator (or fast breeder): different projects and ideas are presented, notably mini-reactors

  17. Nuclear situation in Japan; La situation du nucleaire au Japon

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    This analysis takes stock on the nuclear situation in Japan. It discusses the ambitious equipment program in collaboration with the France, the destabilization of the japanese nuclear industry following the accidents and the energy policy evolutions. It presents the projects of the japanese nuclear industry: the Monju reactor restart, the Pluthermal project, the reprocessing power plant of Rokkasho Mura, the new reactors, the russian weapons dismantling, the ITER site selection and the buy out of Westinghouse by Toshiba. (A.L.B.)

  18. Nuclear toxicology. To detect, to clean; Toxicologie nucleaire. Dectecter, depolluer

    Energy Technology Data Exchange (ETDEWEB)

    Garcia, D. [CEA Cadarache (IBEB), Lab. de Bioenergetique Cellulaire, 13 - Saint-Paul-lez-Durance (France); Lecomte-Pradines, C. [Institut de Radioprotection et de Surete Nucleaire (IRSN/DEI), Lab. de Radioecologie et d' Ecotoxicologie, 13 - Saint-Paul-lez-Durance (France); Quemeneur, E. [CEA Valrho (IBEB), Lab. de Radioecologie et d' Ecotoxicologie Nucleaire, 30 - Marcoule (France); Petitot, F. [CEA Centre de Pierrelatte, Institut de Radioprotection et de Surete Nucleaire, (IRSN-DRPH-SRBE), Lab. de Radiotoxicologie Experimentale, 26 (France); Souidi, M.; Bertho, J.M. [CEA Fontenay-aux-Roses, Institut de Radioprotection et de Surete Nucleaire, (IRSN-DRPH-SRBE), Lab. de Radiotoxicologie Experimentale 92 (France); Junot, Ch. [CEA Saclay (iBiTec-S/SPI), Lab. d' Etude du Metabolisme des Medicaments, 91 - Gif-sur-Yvette (France); Malard, V. [CEA Valrho (IBEB-SBTN), Lab. de Biochimie des Systemes Perturbes, 30 - Marcoule (France); Berthomieu, C.; Chapon, V. [CEA Cadarache (IBEB), Lab. des Interactions Proteine Metal, 13 - Saint-Paul-lez-Durance (France); Gilbin, R.; Misson-Pons, J. [CEA Cadarache, Institut de Radioprotection et de Surete Nucleaire (IRSN/DEI), Lab. de Radioecologie et d' Ecotoxicologie, 13 - Saint-Paul-lez-Durance (France); Vavasseur, A. [CEA Cadarache (IBEB), Lab. des Echanges Membranaires et Signalisation, 13 - Saint-Paul-lez-Durance (France); Richaud, P. [CEA Cadarache (IBEB), Lab. de Bioenergetique et Biotechnologie des Basteries et Microalgues, 13 - Saint-Paul-lez-Durance (France); Ansoborlo, E.; Taran, F.; Benech, H.; Fattal, E.; Tsapis, N.; Menetrier, F.; Deverre, J.R.; Burgada, R. [CEA Marcoule (DEN/DRCP/CETAMA), 30 (France)

    2009-01-15

    This file shows two complementary parts: one aiming to a better detection of exposure for man and environment and and other one relative to the treatments to be used when there is a contamination. The development of biological captors is a research axis that could be very useful for nuclear toxicologists that wish to dispose of perceptible measurement tools. In the same idea biological markers could be an important help to determine the toxic quantity in organism in case of internal radioactive contamination. About remedial actions, bacteria are able to reduce, to oxide, to capture pollutants and then it is not insane to use them in efficient and low cost remediation for waters or contaminated lands, especially by trace metals or radioactive compounds. Next to them, plants can offer the same service it is the case for sunflower able to treat water loaded in uranium. This file ends with a review of the different treatments known nowadays as therapies for contamination by radioisotopes used in nuclear industry. (N.C.)

  19. Indium-Gallium Radiation Contour of the IRT Nuclear Reactor; Circuit d'activation d'indium-gallium dans le reacteur nucleaire IRT; Indij-gallievyj radiatsionnyj kontur yadernogo reaktora IRT; Circuito de radiaciones de indio-galio del reactor IRT

    Energy Technology Data Exchange (ETDEWEB)

    Breger, A K; Ryabukin, Y S; Tulkes, S G; Volkov, E N

    1960-07-15

    Following on theoretical work already published, an indium-gallium radiation contour of the IRT nuclear reactor has been prepared, and represents a powerful new source of gamma-radiation. The first contour of this type ''RK-1'' was prepared on the IRT reactor at the Physics Institute of the Academy of Sciences of the Georgian SSR. The paper gives the activation calculations for indium-gallium alloy; the structural components of RK-1 and their arrangement in the reactor tank and the hot cell; the devise for feeding liquid and gaseous substances into the irradiation zone; and the conveyor for solid substances to be irradiated. When the IRT reactor is at a power of 2000 kW, the radiation strength of the contour is equivalent to that of a gamma-emitter having an activity of 20,000 g. Ra equivalent. The prospects for the use of the indium-gallium radiation contour for research and semi-industrial purposes are discussed. (author) [French] A la suite de la publication d'un ouvrage theorique, on a etabli autour du reacteur nucleaire IRT un circuit d'activation d'indium-gallium qui represente une nouvelle source de rayonnements gamma de grande intensite. Le premier circuit de ce type ''RK-1'' a ete etabli sur le reacteur IRT a l'Institut de physique de l'Academie des sciences de la RSS de Georgie. Les auteurs donnent les calculs de l'activation pour l'alliage indium-gallium; ils indiquent les elements structurels du RK-1 et leur disposition dans le reservoir et dans la cellule de haute activite du reacteur; ils decrivent le dispositif permettant d'introduire des substances liquides et gazeuses dans la zone d'irradiation et le systeme qui transporte les substances solides a irradier. Lorsque le reacteur IRT fonctionne a 2 000 kW, la puissance de rayonnement du circuit equivaut a celle d'un emetteur gamma ayant une activite equivalente a 20 000 grammes de radium. Les auteurs examinent les perspectives d'emploi de ce processus pour la recherche et a des fins semi

  20. Fission Data and Nuclear Technology; Constantes de Fission et Technologie NucleAire; 0414 0410 041d 041d 042b 0415 . 041e 0414 0415 041b 0415 041d 0418 0418 0418 042f 0414 0415 0420 041d 0410 042f 0422 0415 0425 041d 041e 041b 041e 0413 0418 042f ; Datos Sobre la Fision y Tecnologia Nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Hanna, G. C. [Chalk River Nuclear Laboratories, Chalk River, ON (Canada)

    1965-07-15

    Accurate nuclear data for fissile nuclei are required not only by reactor designers, but also by reactor physicists for the interpretation of integral experiments, e.g. studies of the change of reactivity with irradiation. Some of the requests that have been made for such fission data, and the reasons behind them, are discussed, along with the progress that has been made towards their fulfilment. An attempt is made to outline those areas where better data are required. (author) [French] On a besoin de valeurs exactes des constantes nucleaires concernant les noyaux fissiles, non seulement pour les etudes de reacteurs, mais egalement pour la physique des reacteurs lorsqu'on veut interpreter les experiences integrales, c'est-a-dire dans les etudes sur les modifications de la reactivite avec l'irradiation. L'auteur discute certaines des demandes de renseignements sur les constantes de fission, les raisons pour lesquelles elles ont ete faites et la mesure dans laquelle elles ont pu etre satisfaites. Il s'efforce egalement de delimiter les domaines dans lesquels on aurait besoin de valeurs plus precises. (author) [Spanish] No solo quienes trabajan.en el proyecto de reactores requieren datos nucleares exactos sobre los nucleos fisionables, sino que tambien los fisicos de reactores los necesitan para interpretar los resultados de experimentos integrales, como por ejemplo, en los estudios sobre la variacion de la reactividad en funcion de la irradiacion. El autor describe algunas de las peticiories de datos de esa clase que se han formulado, asi como los adelantos realizados con objeto de satisfacerlas. Tambien indica, en lineas generales, aiquellas esferas en las que se necesitan datos mas amplios y exactos. (author) [Russian] Tochnye jadernye dannye o rasshhepljajushhihsja jadrah neobhodimy ne tol'ko konstruktoram reaktorov, no takzhe i fizikam-reak- torshhikam dlja interpretacii integral'nyh jeksperimentov, to est' dlja izuchenija izmenenija reaktivnosti po mere

  1. "Občasné" a "dočasné" rezidence Jana Lucemburského v Lucembursku, Francii a Itálii

    Czech Academy of Sciences Publication Activity Database

    Benešovská, Klára

    2008-01-01

    Roč. 11, - (2008), s. 147-167 ISSN 0862-979X. [Dvory a rezidence ve středověku II. Praha, 18.10.2007-19.10.2007] Institutional research plan: CEZ:AV0Z80330511 Keywords : Gothic architecture * 14th century * John of Luxembourg * residences Subject RIV: AL - Art, Architecture, Cultural Heritage

  2. ASN guide project: complete cleaning-up modalities acceptable in nuclear base installations in France - ASN guide project nr 14 - Release of 21/06/2010

    International Nuclear Information System (INIS)

    2010-01-01

    As any nuclear base installation evolves during its exploitation, some premises or buildings may change of use or be destroyed. In the first case, a complete cleaning up might be necessary to get rid of radioactive products. In order to deal with this issue, after a brief recall of the regulatory context and references, and a recall of the general doctrine of waste management in nuclear base installations in France, this guide project presents the principles for a complete cleaning up of structures belonging to an area containing nuclear wastes. It describes the modalities of definition of three different and successive defence lines. It defines the requirements in performing cleaning-up operations, the requirements in terms of quality insurance, and the different administrative procedures (before, during and after cleaning-up works). Some particular cases are addressed

  3. Reactor Radiation Loops as Large Gamma Sources; Boucles d'irradiation des reacteurs nucleaires utilisees comme sources gamma intenses; Radiatsionnye kontury yadernykh reaktorov kak moshchnye gamma-istochniki; Empleo de circuitos de irradiacion de los reactores como fuentes gamma de gran intensidad

    Energy Technology Data Exchange (ETDEWEB)

    Ryabukhina, Yu. S.

    1963-11-15

    . On a etudie le comportement de deux alliages eutectiques de l'indium en presence de certains materiaux de construction; la premiere installation a ndium-gallium est entree en service au debut de 1960. Des travaux ulterieurs ont permis d'equiper le reacteur IRT de l'Academie des sciences de Georgie d'une boucle modele permettant d'obtenir dans le.canal d'irradiation une activite maximum equivalent a environ 100 g de radium, et d'installer une boucle d'essai a indium-gallium-etain dans le canal du reacteur IRT appartenant a l'Institut de l'energie atomique de l'Academie des sciences de l'URSS. Enfin, en 1962, une boucle a indium - gallium - etain a ete mise en service dans le reacteur IRT de l'Academie des sciences de Lituanie, en vue d'executer des irradiations a une echelle semi-industrielle. Son activite maximum atteignait, dans le dispositif d'irradiation, un niveau equivalent a 30 000 g de radium. Le memoire se compose des quatre parties suivantes: 1. ''Calcul des boucles d'irradiation''; les auteurs generalisent les resultats des travaux sur les methodes de calcul des boucles d'irradiation. 2. ''Modele d'une boucle d'irradiation a indium-gallium pour le reacteur IRT-2000 de Tbilisi''; les auteurs decrivent le fonctionnement de la boucle. 3. ''Boucle d'irradiation a indium-gallium-etain du reacteur nucleaire IRT de l'Academie des sciences de Lituanie''; les auteurs decrivent le fonctionnement de la boucle. 4.

  4. Economic Aspects of Air and Gas Cleaning for Nuclear Energy Processes; Aspects Economiques de l'Epuration de l'Air et des Gaz au Cours des Operations Nucleaires; 042d 041a 041e 041d 041e 0414 0; Aspectos Economicos de la Depuracion del Aire y de los Gases en los Procesos de Obtencion de Energia Nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Silverman, Leslie [Harvard School of Public Health, Boston, MA (United States)

    1960-07-01

    In this paper the basic requirements for control of gaseous and particulate effluents are given as applied to problems of feed material production, isotope separation, fuel element fabrication, fuel recovery and reactor operation. There are also instances where non-radioactive nuclear materials with toxic or nuisance effluents such as from beryllium and zirconium production are of concern and these too must be controlled at reasonable costs. The factors involved in capital and operating costs of gas cleaning equipment and the types of applications in the United States are described in some detail. Gaseous effluent problems have, of course, been attacked and controlled by several types of device but their performance has been measured on a comparable basis. It is thus possible to judge operating characteristics on an economic basis as related to power consumption, adsorbent costs, space charges, corrosion problems and other operational factors. The United States Atomic Energy Commission through its contract with the Harvard University Air Cleaning Laboratory has initiated an evaluation program with cooperation, from the various facilities and contractors to the Commission. In this study the basic factors necessary to obtain quantitative cost delineation and evaluation have been outlined and some preliminary findings will be presented. The paper also presents a review of other economic studies made in the United States on particular process or facility applications. (author) [French] Le memoire definit les regles fondamentales auxquelles doit obeir le controle des effluents gazeux et particulaires dans les domaines suivants : production des matieres destinees a alimenter les reacteurs, separation des isotopes, fabrication des cartouches de combustible, recuperation du combustible et fonctionnement des reacteurs. De plus - et c'est notamment ce qui se passe avec la production de beryllium et de zirconium -- il y a des cas ou des matieres nucleaires non radioactives

  5. Organizing a complex transport while guaranteeing safety and transparency: the example of vitrified wastes sent back to Germany

    International Nuclear Information System (INIS)

    Krochmaluk, Julie; Lebrun, Marc; Delmestre, Alain; Barbey, Pierre; Bonvalot, Vanessa; Belleville, Didier; Rollinger, Patrice; Alter, Ulrich

    2012-01-01

    This chapter is made of several small articles entitled: - 'Les controles avant le depart du convoi franco-allemand' (Controls before the departure of the French-German convoy); - 'La supervision des transports de matieres radioactives: une approche extensive de la surete des operations' (The supervision of radioactive material transports: an extended approach of operation safety); - 'Le dispositif d'information du public sur le transport des substances radioactives mis en place par l'ASN' (The plan implemented by the ASN for public information on nuclear materials transport); - 'Le recours de l'ASN a l'expertise de l'ACRO sur le convoi de colis de dechets vitrifies vers l'Allemagne' (The appeal of the ASN to the ACRO's expertise on the vitrified parcel convoy to Germany); - 'La participation du collectif STOP-EPR a l'inspection de l'ASN du convoi de colis de dechets vitrifies vers l'Allemagne' (The participation of the STOP-EPR collective to the control by the ASN of the vitrified parcel convoy to Germany); - 'La securite et la surete: des valeurs que le Groupe SNCF partage' (Security and safety: values which are shared by the SNCF Group); - 'Le transport de matieres nucleaires entre la France et l'Allemagne au cours des 40 dernieres annees' (Transport of nuclear materials between France and Germany during the last 40 years). Addressing the case of vitrified wastes transported back to Germany, the articles indicate the controls performed in France before convoy departure, discuss the approach adopted for the safety of radioactive material transport, comment the management of public information by the ASN for such transports, comment the intervention of the ACRO (Association for the control of radioactivity in western France) on the request of the ASN and the participation of a collective group (STOP-EPR) to the inspection of a convoy, outline the commitment of the French Railways (SNCF) in terms of security and safety, and give a qualitative and quantitative

  6. The Problems of Controlling Defects in the Materials Used for the First Czechoslovak Nuclear-Power Station; Problemes de Controle des Defauts dans les Materiaux Utilises a la Premiere Centrale Nucleaire de Tchecoslovaquie; Problemy defektoskopicheskogo kontrolya stroitel'nykh materialov reaktora pervoj chekhoslovatskoj atomnoj ehlektrostantsii; Problemas de Control de Defectos en los Materiales Utilizados en la Primera Central Nuclear de Checoslovaquia

    Energy Technology Data Exchange (ETDEWEB)

    Radislav, Filipp [Zavody Im.V.I. Lenina, Pl' zen, Czechoslovakia (Czech Republic)

    1965-09-15

    cassettes. In radiographing thick welds, betatrons of Czechoslovak manufacture are used. The paper describes the methods used for testing and the results obtained and compares the Czechoslovak 15-MeV betatron with the Siemens' betatron. (author) [French] Le memoire donne une description succincte de la cuve du reacteur de la premiere centrale nucleaire de Tchecoslovaquie. En raison des specifications rigoureuses auxquelles doivent repondre les methodes de construction et d'assemblage de la cuve du reacteur, en acier inoxydable faiblement allie de grande epaisseur (650 mm), il a fallu elaborer une methode de controle non destructif du materiau de base et des soudures, fondes sur l'emploi de ' temoins ' . Pour controler la qualite du materiau de base et des sourdures, on utilise essentiellement des ultrasons puises et une sonde. Le memoire decrit les methodes d'essais et l'evaluation des donnees au cours de l'examen du materiau de base, ainsi que le procede qui permet de verifier la qualite des soudures electriques a scorie, des soudures en atmosphere de gaz carbonique et des soudures a l'arc faites a la main. Le controle des plaques forgees et laminees se fait au moyen d'un dispositif automatique de defectoscopie qui a ete mis au point en Tchecoslovaquie. Ce dispositif se compose de deux parties: un mecanisme mobile et un detecteur a ultrasons du type U1D-A2, de fabrication tchecoslovaque. Il comprend plusieurs elements inedits. On a compense l'effet de la distance sur l'ampleur du signal declenche par un defaut de maniere que cette ampleur reste constante. On a compense aussi l'effet du aux irregularites de la liaison acoustique, les impulsions etant communiquees a un dispositif d'enregistrement a distance. L'importance du defaut est evalue a l'aide d'unattenuateur. On metau point un dispositif automatique pour controler une surface cylindrique verticale. Les soudures d'assemblage circulaire doivent etre verifiees a une temperature elevee. Dans les usines V. I. Lenine de

  7. High-Volume Non-Destructive Test Applications at the Hanford Atomic Products Operation; Applications Industrielles des Essais Non Destructifs a l'Etablissement Nucleaire de Hanford; Provedenie bol'shogo chisla nedestruktivnykh ispytanii v ''khenford atomik prodakts opereishen''; Ensayos No Destructivos en Gran Escala Aplicados en Hanford

    Energy Technology Data Exchange (ETDEWEB)

    Worlton, D. C. [Pacific Northwest Laboratory, Battelle Memorial Institute, Richland, WA (United States)

    1965-10-15

    patterns whose size and shape reveal defect magnitude, location within the tube wall, and depth. Probe wobble and harmless tube kinks and bends are plotted with a characteristic pattern readily distinguishable from genuine defects. Results of applying the test to 750 000 ft of installed tubing under difficult field conditions are summarized. (author) [French] On a recours a des essais non destructifs - rapides, surs et automatiques - pour assurer la securite et l'efficacite des operations critiques a Hanford. On utilise couramment des methodes de controle tres sensibles, fondees sur les courants de Foucault et les ultrasons, pour verifier avec le maximum d'assurance et dans le minimum de temps la qualite d'importants volumes de matieres et produits. Le memoire decrit les appareils de controle utilises pour s'assurer de la qualife de la fabrication des combustibles nucleaires a Hanford. Ces appareils, qui font partie integrante de l'equipement de fabrication, appliquent le principe de l'attenuation des ondes ultrasonores pour controler la structure granulaire de barreaux d'uranium non gaine, les ultrasons et les courants de Foucault pour controler la liaison entre l'uranium et sa gaine en aluminium ainsi que l'epaisseur de cette derniere (1 mm), et une nouvelle methode ultrasonore (large bande, haute resolution) pour la detection des defauts dans les soudures aux extremites des cartouches de combustible. Des methodes combinees (courants de Foucault et ultrasons) sont appliquees simultanement pour l'inspection complete d'un element combustible en neuf secondes; les elements defectueux sont rejetes automatiquement. Le memoire expose en detail les methodes ultrasonores perfectionnees pour le controle des gaines de combustible a parois minces. Des traducteurs speciaux a forte focalisation sont utilises avec un circuit a bande large pour produire des ondes de rotation pures dans un tube de 0,37 mm d'epaisseur. Les ondes de Lamb et autres mouvements ondulatoires complexes sont

  8. Impressions from a visit by the ASN of the Laue Langevin Institute research reactor in Grenoble

    International Nuclear Information System (INIS)

    Nifenecker, H.

    2011-01-01

    After having recalled some specific characteristics of the Laue Langevin Institute research reactor (fuel type, cooling system, power, fuel management, fuel storage pool), the author reports the examination of the emergency procedures and of the reactor maintenance. He describes two exercises which respectively simulated the occurrence of an earthquake and that of a flooding due to a dam breaching

  9. Regionalismus v současné české architektuře

    Czech Academy of Sciences Publication Activity Database

    Švácha, Rostislav

    2006-01-01

    Roč. 6, č. 3 (2006), s. 48-51 ISSN 1801-089X Institutional research plan: CEZ:AV0Z80330511 Keywords : Czech architecture * regionalism * 20th century Subject RIV: AL - Art, Architecture, Cultural Heritage

  10. Cloud computing: vývoj a současný stav

    Directory of Open Access Journals (Sweden)

    Václav Sova Martinovský

    2018-06-01

    Full Text Available This article introduces the area of cloud computing with emphasis on businesses and organizations. It includes research of published papers on topic of cloud computing based on metaanalysis and SLR. Summary of relevant advantages both from the user and provider perspective was assembled as well as a list of barriers to even broader adoption of the cloud computing technology. Three databases (EBSCO, ProQuest and Web of Science were used as a source of data for the literature review phase. An analysis of the number of articles dealing with the cloud computing top has been carried out to date. The annual number of publications is compared to the size of the cloud computing market. Frequency analysis at a keyword level was performed in the 25,000-records dataset gathered from the WoS database. This analysis was conducted over the entire monitored period, and only for 2017, to capture the latest trends. There were identified the most frequently used key words in publications about cloud computing: virtualization, security, big data, mobile cloud computing and internet of things. For each of these keywords, a brief summary is given based on the literature search, with an emphasis on the outlook for the future and market position.

  11. Status of radiation protection in interventional radiology. Assessment of inspections in 2009 by the ASN

    International Nuclear Information System (INIS)

    2011-01-01

    This report first describes the organization of inspections performed in health institutions, indicates the inspected establishments, the types of fixed installations in interventional radiology, the use of imagery in the operating theatre, and discusses the regulatory arrangements applicable to interventional radiology (in the Public Health Code, in the Labour Code). Then, the report discusses the results of inspections regarding radiation protection in interventional radiology: application of public health code arrangements (justification, patient training in radiation protection, radiological procedures and protocols, patient dosimetry monitoring), application of Labour Code arrangements (designation of the person with expertise in radiation protection, risk assessment and delimitation of monitored and controlled areas, workstation analysis, workers' training in radiation protection, individual protection equipment, workers' dosimetric monitoring, workers' medical monitoring, radiation protection technical controls), significant events, radiation protection in operating theatre. Propositions are stated regarding the differences noticed within or between the health establishments, the methodological and organisational difficulties faced by persons with expertise in radiation protection (PCR), the need of an interdisciplinary team

  12. Conserved water-mediated H-bonding dynamics of catalytic Asn ...

    Indian Academy of Sciences (India)

    Prakash

    Extensive energy minimization and molecular dynamics simulation studies up to 2 ns ... Conserved water in molecular recognition; MD simulation; plant cysteine protease ..... Mustata G and Briggs J M 2004 Cluster analysis of water molecules.

  13. Tazatel, dotazovaný - dočasní "přátelé"

    Czech Academy of Sciences Publication Activity Database

    Nosková, Jana

    -, č. 35 (2004), s. 121-126 ISSN 1211-5770 Institutional research plan: CEZ:AV0Z9058907 Keywords : ethic s * fieldwork * relationship between interviewew and interviewee Subject RIV: AC - Archeology, Anthropology, Ethnology

  14. Vztah theologie a filosofie u Órigena a úkoly současné dogmatiky

    Czech Academy of Sciences Publication Activity Database

    Milko, Pavel

    2007-01-01

    Roč. 2, č. 2 (2007), s. 3-29 ISSN 1337-0111 R&D Projects: GA ČR GP401/07/P534 Institutional research plan: CEZ:AV0Z90920516 Keywords : Órigenés, ca 185-ca 253 * doctrinal the ology * philosophy Subject RIV: AA - Philosophy ; Religion

  15. Současné poznatky o obecné strupovitosti hlíz brambor

    Czech Academy of Sciences Publication Activity Database

    Krištůfek, Václav; Diviš, J.; Marečková, M.; Kopecký, J.

    2015-01-01

    Roč. 63, č. 2 (2015), s. 75-76 ISSN 0139-6013 R&D Projects: GA MZe QJ1210359 Institutional support: RVO:60077344 Keywords : common scab * potatoes Subject RIV: GF - Plant Pathology, Vermin, Weed, Plant Protection

  16. Estetika ve sportu v současné době

    OpenAIRE

    Fiřt, Martin

    2009-01-01

    Thesis title: The present sport aesthetics Aim of the thesis: To define an aestethics of sports in 21st century, it's particular appearance, essence and development.Description of terms "aesthetics", "sport", "experienced aesthetics of sport" , "the beauty of the human body". As well as terms "harmony in sports", Greek kalokaghatia and modern trends in sport disciplines. Method: A background research was conducted based on available specialised literature. Compilation of knowledge was created...

  17. Thirteen years and counting: Outcomes of a concurrent ASN/BSN enrollment program.

    Science.gov (United States)

    Heglund, Stephen; Simmons, Jessica; Wink, Diane; D'Meza Leuner, Jean

    In their 2011 report, The Future of Nursing, the Institute of Medicine called for 80% of the nursing workforce to be comprised of baccalaureate prepared Registered Nurses by the year 2020. One suggested approach to achieve this goal is the creation of programs that allow students to progress through associate and baccalaureate nursing preparation simultaneously. This paper describes the University of Central Florida's 13-year experience after implementing a Concurrent Enrollment Program. Development and structure of the program, advisement and curriculum details, facilitators and barriers are described. Data on National Council Licensure Examination for Registered Nurses pass rates, completion rates, comparison with traditional RN-BSN students, and progression to graduate school are also included. The Concurrent Program model described here between a specific university and state college partners, demonstrated positive outcomes that support achievement of the Institute of Medicine's goals. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. Assessment of pressurized nuclear equipment compliance - ASN guide no. 8, version of 04/09/2012

    International Nuclear Information System (INIS)

    2012-01-01

    This document describes the modalities according to which the compliance assessment of pressurized nuclear equipment must be performed by inspecting organisations according to a decree of December 1999 and an order of December 2005. After an indication of reference documents and some technical definitions, this guide describes the equipment classification and the principles of intervention. These principles concern the assessment request and the various assessment tasks to be performed by the inspecting organisation

  19. Květena Brna - současný stav poznání

    Czech Academy of Sciences Publication Activity Database

    Lososová, Z.; Šumberová, Kateřina; Tichý, L.; Danihelka, Jiří; Vymazalová, M.

    2015-01-01

    Roč. 63, č. 6 (2015), s. 289-292 ISSN 0044-4812 R&D Projects: GA ČR GB14-36079G Institutional support: RVO:67985939 Keywords : grid mapping * neophytes * city landscape Subject RIV: EH - Ecology, Behaviour

  20. Kluzáky v současném letectví

    OpenAIRE

    Schoř, Pavel

    2009-01-01

    Tato bakalářská práce pojednává v úvodu o stručné historii kluzáku. Druhá kapitola je věnována vysvětlení základních principů letu bezmotorového letadla včetně způsobu, jak může bezmotorový kluzák stoupat. Jsou zde také uvedeny používané způsoby vzletu kluzáků. Ve všech kapitolách jsou příklady uváděné především na kluzáku Standard Cirrus, je to zejména kvůli jeho velkému rozšíření v ČR a jeho snadné finanční dostupnosti. Ve třetí kapitole jsou rozebrány jednotlivé přírodní principy, které js...

  1. Gastroturismus - aktuální trend v současném turismu

    OpenAIRE

    Šejdová, Barbora

    2013-01-01

    This bachelor thesis deal with culinary tourism, as a new trend of tourism. Based on the definition of the field uses the scientific method of bibliographic search and statistical data. It focuses on the concept of inclusion in the typology of tourism. It issues the impact of tourism on the economy and the role of multiplier effects within the general theme. The practical part deals with culinary tourism and it's conception in Austria. First general issues of Austrian tourism are analyzed, wi...

  2. Heterologous gln/asn-rich proteins impede the propagation of yeast prions by altering chaperone availability.

    Directory of Open Access Journals (Sweden)

    Zi Yang

    Full Text Available Prions are self-propagating conformations of proteins that can cause heritable phenotypic traits. Most yeast prions contain glutamine (Q/asparagine (N-rich domains that facilitate the accumulation of the protein into amyloid-like aggregates. Efficient transmission of these infectious aggregates to daughter cells requires that chaperones, including Hsp104 and Sis1, continually sever the aggregates into smaller "seeds." We previously identified 11 proteins with Q/N-rich domains that, when overproduced, facilitate the de novo aggregation of the Sup35 protein into the [PSI(+] prion state. Here, we show that overexpression of many of the same 11 Q/N-rich proteins can also destabilize pre-existing [PSI(+] or [URE3] prions. We explore in detail the events leading to the loss (curing of [PSI(+] by the overexpression of one of these proteins, the Q/N-rich domain of Pin4, which causes Sup35 aggregates to increase in size and decrease in transmissibility to daughter cells. We show that the Pin4 Q/N-rich domain sequesters Hsp104 and Sis1 chaperones away from the diffuse cytoplasmic pool. Thus, a mechanism by which heterologous Q/N-rich proteins impair prion propagation appears to be the loss of cytoplasmic Hsp104 and Sis1 available to sever [PSI(+].

  3. Media w życiu małego dziecka. Badania własne

    OpenAIRE

    Kołodziejczyk, Anna

    2012-01-01

    Over the past decade infants' and toddlers' time spent with media has notably increased. At present, there is limited empirical knowledge regarding how children in different countries use media, how environmental variables influence children's activities. Presented study examined 343 children's aged 0;6 to 6;6 media use. The study provides baseline data about: which media do very young children use, and how much time do they spend using them, how old are children when they first starts using ...

  4. Současné politické konflikty v oblasti Afrického rohu

    Directory of Open Access Journals (Sweden)

    Alemayehu Kumsa

    2012-12-01

    Full Text Available Violent conflict is very old in human society. The development of military technology brought with itself the worst tragedies loss of human live and material devastation in the second half of 20th century in the Horn of Africa. This region is one of the centers of various political violent conflicts in the world, according to length of these violent conflicts, the number of death of people, mainly civilian, refugees and internal displaced persons (IDP. This study elucidates the root causes of long wars in the Horn of Africa focusing mainly on South Sudan and Somalia. It also illustrates how the Super Powers during the Cold War helped their client states to prolong the suffering of people in the region. When Socialist system disappeared from Eastern Europe, Mengistu Haile Mariam's and Siyad Barre's regime ignominiously collapsed. In Ethiopia Amhara power elite, who ruled the Empire state from 1889 to 1991 lost their state power and Tigrian guerrilla fighters captured it through the power of the gun, Eritrea gained its independence from Ethiopia, South Sudan is emerging from long heinous war to independence. The violent conflict in Somalia transformed after the old regime demise in 1991 and the new leaders unable to build new central government. Somalia is fragmented and became the good example of failed state in the theory of contemporary political sociology. The paper tries to explain these complex violent conflicts in this part of Africa.

  5. Současné politické konflikty v oblasti Afrického rohu

    Directory of Open Access Journals (Sweden)

    Alemayehu Kumsa

    2018-01-01

    Full Text Available Violent conflict is very old in human society. The development of military technology brought with itself the worst tragedies loss of human live and material devastation in the second half of 20th century in the Horn of Africa. This region is one of the centers of various political violent conflicts in the world, according to length of these violent conflicts, the number of death of people, mainly civilian, refugees and internal displaced persons (IDP. This study elucidates the root causes of long wars in the Horn of Africa focusing mainly on South Sudan and Somalia. It also illustrates how the Super Powers during the Cold War helped their client states to prolong the suffering of people in the region. When Socialist system disappeared from Eastern Europe, Mengistu Haile Mariam’s and Siyad Barre’s regime ignominiously collapsed. In Ethiopia Amhara power elite, who ruled the Empire state from 1889 to 1991 lost their state power and Tigrian guerrilla fighters captured it through the power of the gun, Eritrea gained its independence from Ethiopia, South Sudan is emerging from long heinous war to independence. The violent conflict in Somalia transformed after the old regime demise in 1991 and the new leaders unable to build new central government. Somalia is fragmented and became the good example of failed state in the theory of contemporary political sociology. The paper tries to explain these complex violent conflicts in this part of Africa.

  6. Současná věda o člověku

    Czech Academy of Sciences Publication Activity Database

    Černý, Viktor; Brůžek, J.

    2016-01-01

    Roč. 64, č. 5 (2016), s. 202 ISSN 0044-4812 Institutional support: RVO:67985912 Keywords : anthropology Subject RIV: AC - Archeology, Anthropology , Ethnology http://ziva.avcr.cz/files/ziva/pdf/soucasna-veda-o-cloveku.pdf

  7. ASN guide project. Protection of base nuclear installations against external flooding

    International Nuclear Information System (INIS)

    2010-01-01

    This guide aims at defining criteria to be taken into account to assess risks of flooding of a nuclear installation in case of external flooding, at proposing an acceptable method to assess such risks, at listing recommendations to define protection means adapted to the peculiarities of the flood risk and implemented by the operators with respect to the life phases of the installation, and in taking the climate change into account. The first part proposes an approach allowing the identification of reference situations which are to be taken into account for the flood risk. The second part deals with the quantification of parameters which characterize physical phenomena associated with these situations. The third part identifies the peculiarities of the flood risk as well as the guiding principles for designing options and protection mean selection with respect to a given flood risk

  8. SBMAC: Smart Blocking MAC Mechanism for Variable UW-ASN (Underwater Acoustic Sensor Network Environment

    Directory of Open Access Journals (Sweden)

    Soo-Hyun Park

    2010-01-01

    Full Text Available In this paper, several MAC scheduling methods applicable to an underwater environment are proposed. Besides, a new marine communication system model was proposed to improve the reliability of the proposed SBMAC method. The scheme minimizes transmission of control frames except for data transmission and various transmission methods and ACK methods can be used together. Simulation models are set indices and analysis of the underwater environment is established to conduct reliable simulations. Consequently, the performance improvement of the proposed method is verified with respect to delay time, data transmission rate, memory utilization, energy efficiency, etc.

  9. Generativita v současném empirickém výzkumu

    Czech Academy of Sciences Publication Activity Database

    Millová, Katarína; Blatný, Marek

    2016-01-01

    Roč. 60, č. 6 (2016), s. 609-621 ISSN 0009-062X R&D Projects: GA ČR GA15-22474S Institutional support: RVO:68081740 Keywords : generativity * personality * well-being * parenting * family * work Subject RIV: AN - Psychology Impact factor: 0.242, year: 2016

  10. Současné české neologismy z oblasti sportu

    OpenAIRE

    Filiačová, Sylva

    2014-01-01

    This bachelor thesis discusses the new appearance of substantive, adjective, verbal, and adverbial phrases in the sports area of the Czech language. The thesis is materially based on the database NEOMAT (Institute of the Czech Language of the Academy of Sciences of the Czech Republic), the databases of the Czech National Corpus, and the Newton Media archive. The first part of the thesis covers the definition of the concept of neologism. The following chapter discusses the ways of genesis of n...

  11. Gas-flow detector for uranium contamination on finned-can surface of a reactor fuel; Detecteur a courant gazeux pour deceler la contamination en uranium des nervures des gaines de combustible nucleaire; Gazopotochnyj detektor zagryazneniya uranom rebristoj poverkhnosti obolochki reaktornykh teplovydelyayushchikh ehlementov; Detector de flujo gaseoso para medir la contaminacion de uranio en la superficie de la vaina de aletas de los elementos combustibles para reactores

    Energy Technology Data Exchange (ETDEWEB)

    Miwa, H; Shiojiri, T; Maeda, Y [Kobe Kogyo Corporation, Okubo, Akashi, Hyogo (Japan)

    1962-04-15

    Calder Hall-type reactor-fuel and all JRR-3 fuels are to be inspected by this counter. (author) [French] Le detecteur a courant gazeux presente par les auteurs est un compteur proportionnel a grille, specialement concu pour deceler la contamination en uranium des nervures des gaines de combustible nucleaire. Un compteur proportionnel classique, compose seulement d'une cathode et d'un collecteur, n'est guere capable de deceler les particules alpha emises par l'uranium contaminant une surface rugueuse telle que les nervures d'une gaine de combustible nucleaire, par suite du manque d'uniformite du champ electrique pres de la surface. C'est pourquoi les auteurs ont construit un compteur proportionnel a grille. Cet appareil, de forme cylindrique, comprend le combustible, une grille, des collecteurs et une cathode, tous les elements etant disposes suivant le meme axe. Le combustible est place au centre de la grille a laquelle on applique une tension negative. L'espace entre le combustible et la grille sert de collecteur d'ions. La grille, faite de fils paralleles minces en tungstene, disposes suivant un cylindre autour du combustible, est reliee a la terre. Les collecteurs sont constitues de 16 minces fils de tungstene disposes de la meme maniere que la grille, mais chaque fil est isole electriquement des autres. Tous les collecteurs sont interconnectes par des resistances de 5 x 10{sup 4} ohms et relies au positif de la haute tension par une resistance. L'espace entre la grille, les collecteurs et la cathode sert a la multiplication du gaz, tout comme dans un compteur proportionnel classique. Chaque resistance de 5 x 10{sup 4} ohms isole la capacite parasite de chaque collecteur. La sortie du detecteur est couplee a un amplificateur a faible impedance d'entree. La faible impedance d'entree diminue aussi l'influence facheuse de la capacite parasite du circuit d'entree. Il en resulte un rapport favorable signal/bruit de fond, ce qui permet une bonne detection des particules

  12. The nuclear law: safety. 2006-2010

    International Nuclear Information System (INIS)

    Bringuier, P.

    2010-01-01

    The author discusses the legal evolutions related to nuclear safety between 2006 and 2010. He identifies three main topics of unequal importance. Firstly, he comments the implementation of an international reference framework which has been completed at the European level and which aims at the harmonization of safety and security rules. Secondly, he comments the creation of the French Nuclear Safety Authority (ASN, Autorite de Surete Nucleaire). Thirdly, he comments the recast of the standard framework in order to update the French law with respect to the international reference framework. This leaded to a new distribution of power and authority, to more complete and constraining procedures, and to the definition of procedures for each step of an installation life cycle

  13. The Radioisotopic Determination of Diffusion Coefficients and Currents in Natural Waters. Surface Collection of Radioactive Fall-Out on a Large Alpine Lake; Determination par detection nucleaire des coefficients de diffusion et des courants dans les eaux naturelles. Evolution de la surface de collection d'un grand lac alpin pour les retombees radioactives; Opredelenie koehffitsienta diffuzii i skorosti techeniya estestvennykh vod pri pomoshchi yadernogo detektirovaniya. Ehvolyutsiya poverkhnosti sbora radioaktivnykh osadkov na bol'shom al'pijskom ozere; Determinacion por deteccion nuclear de los coeficientes de difusion y de las corrientes en las aguas naturales evolucion de la superficie de captacion de un gran lago alpino para las precipitaciones radiactivas

    Energy Technology Data Exchange (ETDEWEB)

    Chesselet, R.; Nordemann, D. [Service d' Electronique Physique, Centre d' Etudes Nucleaires de Saclay (France); Dussart, B. [Centre de Recherches Hydrobiologiques, CNRS, Gif-sur-Yvette (France)

    1963-08-15

    'un coefficient de diffusion pour l'emetteur utilise et a la mesure eventuelle de la vitesse du courant au point ou la mesure est effectuee (dans le cas decrit, le lac Leman). Dans une seconde etape, en correlation avec une etude de geophysique concernant le probleme general des retombees radioactives, les auteurs ont utilise l'apport des retombees radioactives ayant pour origine les essais nucleaires atmospheriques (octobre 1961-janvier 1962). Des mesures de la radioactivite ont ete effectuees chaque jour sur des prelevements d'eau du lac Leman a des profondeurs de 0 m, 10 m, 20 m et sur un collecteur de retombees atmospheriques seches et humides. Malgre la complexite du regime des apports en fonction du temps, l'interpretation des diagrammes obtenus peut contribuer a resoudre le probleme du devenir des produits radioactifs dans les conditions de diffusion et de courants rencontrees. L'utilisation de la diffusion de produits radioactifs en tres faibles quantites et des differentes techniques de detection nucleaires a haute sensibilite actuellement disponibles peut conduire a une meilleure connaissance de la diffusion in situ et du mouvement des masses d'eaux naturelles. (author) [Spanish] En una primera etapa, los autores ha i provecado la difusion in situ de un emisor radiactivo, el sodio-22 en forma de Na{sup +}, de actividad muy baja (inferior al milicurie). La aplicacion de las leyes de la difusion a este caso facilita el calculo de la velocidad de difusion de la ''nube radiactiva''. Por consiguiente, el registro en funcion del tiempo de las actividades medidas con dos detectores gamma dispuestos de modo conveniente permite asignar un coeficiente de difusion ai emisor empleado y, eventualmente, evaluar la velocidad de la corriente en el punto en que se efectua la medicion (en el caso descrito, el lago Leman). En una segunda etapa, en relacion con un estudio geofisico del problema general de las precipitaciones radiactivas, los autores utilizaron la aportacion de las

  14. Nuclear Materials Management in Relation to Safety and Criticality Control: A Study of Non-Inherently Safe Systems; La Gestion des Matieres Nucleaires dans ses Rapports avec la Securite et le Controle de la Criticite; Etude des Systemes a Securite Non Inherente; Obrashchenie s yadernymi materialami s uchetom bezopasnosti i kontrolya za kritichnost'yu. izuchenie sistem dopolnitel'noj avarijnoj zashchity; La Administracion de Materiales Nucleares y sus Relaciones con la Seguridad y el Control de la Criticidad; Estudio de los Sistemas de Seguridad No Inherente

    Energy Technology Data Exchange (ETDEWEB)

    Fruchard, Y. [Commissariat a l' Energie Atomique, Marcoule (France)

    1966-02-15

    a securite inherente. Toutefois, les systemes a securite non inherente restent nombreux dans les installations nucleaires et le recours a l'une ou l'autre des deux premieres methodes devient necessaire. Ces methodes sont liees a la gestion des matieres nucleaires. Dans les installations ou sont manipulees de petites quantites de matieres fissiles, il est souvent possible d'assurer la securite nucleaire en admettant dans chaque salle une masse de matiere fissile inferieure a la masse ciritique minimale. Pour des installations plus importantes, un tel controle, qui repose entierement sur la gestion des matieres, devient impossible. L'auteur examine, dans le cas particulier d'une usine oe traitement de combustibles irradies par voie aqueuse (les combustibles sont a base d'uranium naturel), comment se presente la liaison entre gestion et securite nucleaire. Une telle usine comprend grossierement trois parties au point de vue du controle de la criticite: Dans la premiere partie, traitant des solutions assez diluees, le controle qui s'impose est celui de la concentration. Si ce controle est aise (analyse et compteurs neutrons), il est difficile de s'assurer qu'il ne se forme pas de depots: bien que l'experience ait montre qu'ils n'etaient pas tellement a craindre, le fait bien connu d'un bilan matieres deficitaire reste un souci en matiere de criticite. Dans cette partie, la gestion des matieres, encore imparfaitement realisee, est de premiere importance pour la securite. La deuxieme partie traite des solutions concentrees et des precipites humides. C'est le domaine de la geometrie sure. La gestion des matieres l'interesse moins directement mais reste un facteur de securite important (en cas d'intervention, de nettoyage des appareils, etc.). Un controle par la masse s'impose dans la troisieme partie qui traite des produits secs. La gestion ne presente pas de difficulte particuliere. A ce schema se superpose une partie moins spectaculaire mais qui sur le plan surete est de

  15. La Reggenza et les autorisations : l’application des lois sur les fidéicommis et la mainmorte dans la Toscane des Lorraines (1737-1765

    Directory of Open Access Journals (Sweden)

    Lara Marchi

    2010-05-01

    Full Text Available Date de soutenance : le 19 décembre 2009 à l’ÉHESS 54 Boulevard. Raspail, Paris.Composition du juryMonsieur Gérard Delille, Directeur d’études à l’éHESS (Directeur de thèse, Monsieur Eric Brian, Directeur d’études à l’ÉHESS et Directeur scientifique adjoint de l’INSHS du CNRS, Monsieur Marcello Verga, Professeur à Université de Sciences Politiques« Cesare Alfieri » de Florence, Monsieur Paolo Malanima, Directeur de l’Istituto di Studi sulle Società del Mediterraneo du CNR de Naples et Profes...

  16. Primary Distributions of Nuclear Charge for Fission-Fragment Masses 132, 134, 136 and 137 from Thermal Fission of U{sup 235}; Repartition Primaire de la Charge Nucleaire pour les Fragments de Masse 132, 134, 136 et 137, Provenant de la Fission de {sup 235}U par Neutrons Thermiques; 041f 0415 0420 0414 ; Distribuciones Primarias de las Cargas Nucleares de los Fragmentos de Masa 132, 134, 136 y 137, Resultantes de la Fision del {sup 235}U por Neutrones Termicos

    Energy Technology Data Exchange (ETDEWEB)

    Konecny, E.; Opower, H.; Guenther, H.; Goebel, H. [Physik-Department der Technischen Hochschule Muenchen, Munich and II. Physikalisches Institut der Justus Liebig-Universitaet Giessen, Federal Republic of Germany (Germany)

    1965-07-15

    the statistical error arising from the transformation from 2{pi}- to 4{pi}-distribution, and for various kinetic energies as parameters, are in preparation. (author) [French] A l'aide d'un spectrometre de masse, on separe avec precision les fragments de la fission thermique de {sup 235}U d'apres leur masse et leur energie cinetique dans la microseconde qui suit la fission. Les fragments separes sont retenus dans une emulsion Ilford G 5 sensible aux particules {beta}, qui est placee dans le plan focal du spectrometre. Les emulsions irradiees sont developpees, dans la mesure du possible, apres un delai relativement long par rapport a la periode la plus longue de la serie radioactive consideree. Les periodes de l'ordre de plusieurs jours ou plus longues encoxe ne sont pas prises en consideration, mais il est facile d'appliquer un facteur de correction approprie. Apres avoir developpe les emulsions, on peut observer au microscope toutes les traces {beta} qui prolongent chacune des traces de fragments de fission. La possibilite d'etablir une correlation entre une trace {beta} et une trace de fragment de fission permet d'evaluer le nombre n(x) de fragments de fission possedant un nombre x de traces {beta}, ce qui indique non seulement la longueur moyenne de la serie mais aussi la distribution des particules {beta}. Le nucleide stable de chaque serie etant connu, la distribution des particules {beta} constitue une image exacte de la repartition primaire des charges nucleaires. Au cours des mesures effectuees jusqu'a present, on n'a en-' registre que les particules {beta} emises dans le demi-angle solide forme par la plaque d'emulsion, mais un calcul statistique simple permet d'evaluer la distribution. 4{pi} voulue. Grace a cette methode, on obtient la distribution des particules 0 a des energies cinetiques determinees proches de l'energie cinetique moyenne de chaque fragment pour les masses 132, 134, 136 et 137. Pour les masses 132 et 134, c'est a la couche de neutrons N

  17. Chemical Effects of Nuclear Recoil in Organic Halide Systems: A New Theoretical Treatment and Experimental Verification of the Theory; Effets Chimiques du Recul Nucleaire dans des Systemes Organiques Halogenes: Nouveau Traitement Theorique et Verification Experimentale de la Theorie; Khimicheskie vozdejstviya yadernoj otdachi v organicheskikh galoidnykh sistemakh: novoe teoreticheskoe tolkovanie i ehksperimental'noe podtverzhdenie teorii; Efectos Quimicos del Retroceso Nuclear en Sistemas de Haluros Organicos: Nuevo Tratamiento Teorico y Verificacion Experimental de la Teoria

    Energy Technology Data Exchange (ETDEWEB)

    Kontis, S. S.; Sanitwongs, P.; Weston, M. [Londonderry Laboratory for Radiochemistry, University of Durham, Durham (United Kingdom)

    1965-04-15

    mecanisme de la 'boule de billard' pour le marquage par l'atome chaud, auquel Libby a donne son nom, et les retentions sont exprimees en fonction de deux types de parametres, savoir: 1. la probabilite que le choc entre un atome chaud de radiohalogene et une molecule donnee determine la retention de l'atome chaud dans cette molecule; 2. les limites superieure et inferieure des energies pour lesquelles un atome de brome est dit chaud. Les auteurs montrent comment le premier type de parametre peut etre derive d'experiences sur des melanges binaires d'un halogenure organique et de l'halogene libre correspondant; le second type de parametre doit etre deduit des constantes nucleaires et chimiques. Des etudes sur les systemes C{sub 2}H{sub 5}Br/CCl{sub 4}/Br{sub 2} et C{sub 2}H{sub 5}Br/C{sub 6}H{sub 5}Br/Br{sub 2} ont permis de faire l'essai de ces methodes. Les valeurs de retention calculees (en Utilisant des parametres derives d'etudes des systemes C{sub 2}H{sub 5}Br/Br{sub 2}, CCl{sub 4}/Br{sub 2} et C{sub 6}H{sub 5}Br/Br{sub 2}) concordent avec celles qui sont determinees experimentalement dans des melanges ou la fraction molaire de brome est superieure a 0,1 environ. Par consequent, les auteurs considerent que le mecanisme Libby permet d'expliquer les retentions organiques observees dans ces melanges. Lorsque la fraction molaire de brome devient inferieure a 0,1, les retentions observees augmentent progressivement par rapport aux valeurs calculees, ce qui est sans doute du au fait que d'autres modes de marquage par l'atome chaud interviennent lorsque la concentration en brome n'est pas assez elevee pour assurer un bon 'balayage' des radicaux. (author) [Spanish] Los autores elaboraron metodos para calcular la probable retencion organica de los halogenos radiactivos despues de activar con neutrones mezclas de dos haluros organicos y el correspondiente halogeno libre; Los metodos se basan en la teoria del proceso de ' bolas de billar ' de Hbby para la marcacion con atomos

  18. A future for nuclear sites beyond their service life. Nuclear site value development; Un avenir pour les sites nucleaires en fin de cycle. Valorisation des sites nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-07-01

    As the nuclear industry moves into a new development phase, many facilities built in the fifties and sixties are reaching the end of their service life. Dismantling them and rehabilitating the sites on which they stand is a major industrial challenge which will give rise to a number of new projects. AREVA has more than 20 years' experience in these highly technical fields. As more and more sites reach the end of their service life, AREVA considers nuclear site value development as a fully-fledged industrial activity. The group's competencies in this field have been grouped together to form a dedicated entity: the Nuclear Site Value Development Business Unit, created in 2008. Several billion euros are invested in site value development projects which are far-reaching and complex, and often last for several decades. Long before work actually begins, lengthy studies and preparations are required to schedule operations, select the techniques to be used and optimize costs and deadlines. The Nuclear Site Value Development BU is currently working on four major projects involving its own facilities and those of the CEA: - La Hague: dismantling of the first generation of used fuel recycling facilities. Between 1966 and 1998, almost 5,000 tons of used fuel from graphite-moderated gas-cooled reactors, 4,500 tons of light water reactor fuel, as well as fuel from fast reactors and research reactors, were treated at UP2 400, the very first industrial recycling plant on the La Hague site. - Marcoule: first-time dismantling of a recycling plant. 1,000 rooms to be cleaned up, 30,000 tons of waste to be treated, 30 years of work. - Cadarache: first-time dismantling of a Mox fuel fabrication plant. The Cadarache plant was commissioned in 1962 to fabricate fuel for fast reactors; this was followed by MOX fuel for light water reactors, an activity which continued until the plant was shut down in 2003. - Annecy and Veurey: giving a new lease of life to former industrial sites in built-up areas. AREVA is currently working on a site value development program on two industrial sites in Annecy and Veurey, near Grenoble. Dating back to 1955 and 1957, the sites were created for the manufacture and precision machining of uranium metal. The number of clean-up and dismantling projects is set to rise steadily in the years ahead and site value development will unquestionably become a new nuclear activity in its own right. AREVA is developing the corresponding competencies and expertise: new professions are springing up (value development project manager, scenario and feedback manager, operational dismantling methods manager, flushing operator, etc.) and a dedicated theoretical and practical training program is being put together. Once a nuclear site has been shut down, the long-term dismantling and value development operations make a considerable contribution to the local economy. Site rehabilitation is an environmental necessity and improves nuclear's image in the eyes of the public. As new nuclear projects get off the ground, developing the value of disused sites will free up space for future projects and make a valuable contribution to the nuclear revival.

  19. Nuclear safety and radiation protection report of the Chooz nuclear facilities - 2010; Rapport sur la surete nucleaire et la radioprotection des installations nucleaires de Chooz - 2010

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-06-15

    This safety report was established under the article 21 of the French law no. 2006-686 of June 13, 2006 relative to nuclear safety and information transparency. It presents, first, the facilities of the Chooz nuclear power plant (Ardennes (FR)): 2 PWR reactors in operation (Chooz B, INB 139 and 144) and one partially dismantled PWR reactor (Chooz A, INB 163). Then, the nuclear safety and radiation protection measures taken regarding the facilities are reviewed: nuclear safety definition, radiation protection of intervening parties, safety and radiation protection improvement paths, crisis management, external and internal controls, technical situation of facilities, administrative procedures in progress. The incidents and accidents which occurred in 2010, are reported as well as the radioactive and non-radioactive (chemical, thermal) effluents discharge in the environment. Finally, The radioactive materials and wastes generated by the facilities are presented and sorted by type of waste, quantities and type of conditioning. Other environmental impacts (noise, microbial proliferation in cooling towers) are presented with their mitigation measures. Actions in favour of transparency and public information are presented as well. The document concludes with a glossary and a list of recommendations from the Committees for health, safety and working conditions. (J.S.)

  20. Nuclear safety and radiation protection report of the Flamanville nuclear facilities - 2010; Rapport sur la surete nucleaire et la radioprotection des installations nucleaires de Flamanville - 2010

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-06-15

    This safety report was established under the article 21 of the French law no. 2006-686 of June 13, 2006 relative to nuclear safety and information transparency. It presents, first, the facilities of the Flamanville nuclear power plant (Manche (FR)): 2 PWR reactors in operation (INB 108 and 109), and 1 PWR under construction (Flamanville 3, INB 167). Then, the nuclear safety and radiation protection measures taken regarding the facilities are reviewed: nuclear safety definition, radiation protection of intervening parties, safety and radiation protection improvement paths, crisis management, external and internal controls, technical situation of facilities, administrative procedures in progress. The incidents and accidents which occurred in 2010, are reported as well as the radioactive and non-radioactive (chemical, thermal) effluents discharge in the environment. Finally, The radioactive materials and wastes generated by the facilities are presented and sorted by type of waste, quantities and type of conditioning. Other environmental impacts (noise, water consumption and waste management at Flamanville 3 construction site) are presented with their mitigation measures. Actions in favour of transparency and public information are presented as well. The document concludes with a glossary and a list of recommendations from the Committees for health, safety and working conditions. (J.S.)

  1. Controlling safety at all stage of parcel lifetime

    International Nuclear Information System (INIS)

    Sert, Gilles; Aguilar, Jacques; Clemente, Colette; Sauron, Claire; Labergri, Fabien; Jacob, Emmanuel; Sallit, George; Lourtie, Guy

    2012-01-01

    This chapter is made of several small articles entitled: - 'L'etude des risques lies aux situations extremes pouvant survenir lors du transport des substances radioactives' (The investigation of risks related to extreme situations which may occur during radioactive material transport); - 'Une necessaire diversification de l'expertise: le role du Groupe permanent d'experts pour les transports' (A required diversification of expertise: the role of the permanent group of experts for transports); - 'Vers un nouveau consensus sur les methodes et les parametres de reference a retenir lors des agrements des modeles de colis destines au transport' (Towards a new consensus on methods and reference parameters to be retained during agreements of models of parcels designed for transport); - 'Le controle de la fabrication des emballages par l'ASN' (Control of packaging manufacturing by the ASN); - 'Concevoir et realiser un emballage destine au transport de substances radioactives: l'exemple de la societe ROBATEL' (Designing and manufacturing a package for nuclear material transport: the example of the ROBATEL company); - 'Les transports internes dans les installations nucleaires de base secretes' (Internal transports within secrete base nuclear installations); - 'Les operations de transport interne sur les sites nucleaires' (Transport operations within nuclear sites); - 'Cooperation entre les Autorites competentes britanniques et francaises en matiere de regulation de la surete du transport des substances radioactives' (Cooperation between British and French Authorities in charge of radioactive material transport safety regulation); - 'Inspections et sanctions en Belgique' (Inspections and sanctions in Belgium). While evoking regulations and research studies, the first article comments the various risks (mechanical and thermal risks, and risks related to radiation leakage) associated with radioactive material transport. In an interview, the chairman of the permanent group of

  2. Complementary Safety Assessments for Research Reactors for the French Nuclear Safety Authority

    International Nuclear Information System (INIS)

    Kassiotis, Christophe; Rigaud, Antoine; Evrard, Lydie

    2013-01-01

    The 'Autorite de surete nucleaire' (ASN) requested licensees to undertake stress tests, called complementary safety assessments (CSA), of their installations on May 5th 2011, following the accident that occurred in Japan on March 11th 2011. Their mission consisted in providing feedback on the consequences of potential extreme events. In this process, all the French facilities were divided into three categories of decreasing priority, depending on two main factors: on the one hand, their vulnerability to the various phenomena that led to the Fukushima accident, and on the other hand, the amount of radioactive elements that would be dispersed in the event of a failure of the safety functions. On the 79 high-priority facilities, only five of them are research or experimental reactors (including two currently shutdown or in decommissioning) and their operators (the 'Comissariat a l'energie atomique et aux energies alternatives' (CEA) and the 'Institut Laue Langevin') submitted their reports to the ASN on September 15 th 2011. Concerning the lower-priority facilities, including three other facilities (two research reactors operated by the CEA and a facility operated by ITER Organization) the deadline was September 15 th 2012. Finally, the remaining facilities were not asked to submit a report yet, but they will have to do it later, mainly on the occasion of their next periodic safety review. The analyses of the cliff-edge effects, that may occur in extreme situations (exceptional scale event, combination of several disasters...), led to the definition of a hardened safety core concept by the 'Institut de radioprotection et de surete nucleaire' (IRSN). This hardened safety core of structures, equipment and organizational measures must ensure the ultimate protection of the concerned facilities in extreme situations : it is designed to prevent severe accidents (or curb their progression), limit large scale releases for extreme accidents, and enables the operating teams to

  3. Bohuslav Havránek očima svých současníků

    Czech Academy of Sciences Publication Activity Database

    Dvořáčková, Věra

    2017-01-01

    Roč. 9, č. 1 (2017), s. 22-38 ISSN 1804-1221 R&D Projects: GA ČR(CZ) GA17-22085S Institutional support: RVO:67985921 Keywords : structuralism * Bohuslav Havránek Subject RIV: AB - History OBOR OECD: History (history of science and technology to be 6.3, history of specific sciences to be under the respective headings)

  4. Antonín Randa očima svých současníků

    Czech Academy of Sciences Publication Activity Database

    Velek, Luboš

    2016-01-01

    Roč. 155, č. 8 (2016), s. 673-688 ISSN 0231-6625 Institutional support: RVO:67985921 Keywords : Randa, Antonín * Faculty of Law, Czech University in Prague * Habsburg Monarchy, 1848-1918 Subject RIV: AB - History

  5. Soubor kostí z časně eneolitického objektu v Suchomastech, okr. Beroun

    Czech Academy of Sciences Publication Activity Database

    Kyselý, René

    2015-01-01

    Roč. 19, č. 2 (2015), s. 505-506 ISSN 1214-3553 Institutional support: RVO:67985912 Keywords : archaeozoology * Copper Age * cattle (Bos) * Jordanów culture Subject RIV: AC - Archeology, Anthropology, Ethnology

  6. Students’ health behaviors – own research = Zachowania zdrowotne studentów – badania własne

    Directory of Open Access Journals (Sweden)

    Magdalena Weber-Rajek

    2015-09-01

    Wyniki Średni wynik kwestionariusza IZZ dla całej badanej grupy wynosi 6,96 sten, co stanowi granicę między wynikami średnimi i wysokimi. Najlepsze wyniki kwestionariusza IZZ uzyskali studenci Dietetyki, najgorsze studenci Logistyki. W całej badanej grupie najlepsze wyniki uzyskano  kategorii „prawidłowe nawyki żywieniowe”, najgorsze w kategorii „praktyki zdrowotne”. Wnioski Istnieje potrzeba dalszych badań zachowań zdrowotnych młodzieży i upowszechniania programów promocji zdrowia na wszystkich etapach edukacji.   Słowa kluczowe: zachowania zdrowotne, studenci.

  7. Město a současná religiozita v pohledu sociologie náboženství

    Czech Academy of Sciences Publication Activity Database

    Nešpor, Zdeněk

    2016-01-01

    Roč. 11, č. 3 (2016), s. 78-91 ISSN 1211-7668 R&D Projects: GA ČR(CZ) GA14-15008S Institutional support: RVO:68378025 Keywords : Sociology of religion * urban sociology * city and religion Subject RIV: AA - Philosophy ; Religion

  8. The structure and energetic of AlAsn (n = 1-15) clusters: A first-principles study

    International Nuclear Information System (INIS)

    Guo Ling

    2010-01-01

    Geometric structures of AlAs n (n = 1-15) clusters are reported. The binding energy, dissociation energy, stability of these clusters are studied with the three-parameter hybrid generalized gradient approximation (GGA) due to Becke-Lee-Yang-Parr (B3LYP). Ionization potentials, electron affinities, hardness, and static polarizabilities are calculated for the ground-state structures within the same method. The growth pattern for AlAs n (n = 6-15) clusters is Al-substituted pure As n+1 clusters and it keeps the similar frameworks of the most stable As n+1 clusters (for example AlAs 6 , AlAs 7 , AlAs 9 , AlAs 14 and AlAs 15 clusters) or capping the different sides of the low-lying geometry of As n clusters (for example AlAs 8 , AlAs 10 , AlAs 11 , and AlAs 12 clusters). The Al atom prefer to occupy a peripheral position for n n (n = 1-5, 13) clusters. The odd-even oscillations from AlAs n (n = 5-15) in the dissociation energy, the second-order energy differences, the HOMO-LUMO gaps, the electron affinity, and the hardness are more pronounced. The stability analysis based on the energies clearly shows the AlAs n clusters from n = 5 with an even number of valence electrons are more stable than clusters with odd number of valence electrons.

  9. Increase of doses delivered to patients during medical imagery examinations. Conclusions of 16 September 2010 seminar organized by the ASN

    International Nuclear Information System (INIS)

    2011-01-01

    This document reports the contributions of the participants to the seminar which aimed at discussing the increase of doses delivered in medical imagery, and the actions to undertake to limit this increase. The authors recall the regulatory and legal context regarding the optimization of medical procedures and the organisation of radiation protection for medical exposures, comment the assessment of exposures by medical imagery in 2007, comment the CE marking of medical devices, the recent evolutions in dose optimization of radiology and scanography devices. Other sets of interventions address the application of the justification and optimization principle by professionals (in new scanography practices, in radio-paediatrics), the professional training issue (radiologist continuous training, electro-radiology operator training), the comparison between scanner and RMI (new fields for RMI, imagery benchmark), the assessment of professional practices (tools for continuous professional development of health professionals, medical imagery initiatives in Belgium), and international recommendations (by the IAEA, the WHO, the European Union)

  10. Cestovní ruch v Peru: vývoj, současný stav, vize

    OpenAIRE

    Pošepná, Zdeňka

    2009-01-01

    This thesis deals with development of tourism in Peru from the 19. century to the present-day by means of travel accounts written by travellers mainly from Europe and United States of America. Furthermore, the thesis analyzes present development of tourism in Peru. At first it evaluates today's Peruvian offer of tourist attractions presented by Peruvian guidebooks which compares with demand for these attractions trough the medium of contemporary foreign guidebooks. This analyze is completed b...

  11. Novo-viktoriánský román: současný trend britské fikce

    OpenAIRE

    Szilágyiová, Ester

    2010-01-01

    In 1966 when Jean Rhys wrote Wide Saragasso Sea no one would have guessed that she was starting a new literary movement whose very essence dwelled in re-thinking and rewriting Victorian myths and stories which Sally Shuttleworth named the retro-Victorian novel1. As a matter of fact, John Fowles's The French Lieutenant's Woman published in 1969, brought to public attention the parody of Victorian social, sexual and literary conventions2 but it was really in the 1980's and 1990's that many Brit...

  12. Vliv současných IT trendů na budoucnost šedé literatury

    OpenAIRE

    Savić, Dobrica

    2016-01-01

    This paper deals with emerging information technology (IT) and other trends and their impact on the grey literature. It is based on analysis of the most prevalent trends in general information management and new IT solutions, which will define and impact the digital future of related information management activities, as well as the grey literature. The analysis was done based on seven reports issued in 2016 by five world leading consulting and service companies that have a special interest i...

  13. Současná pozice cestovního ruchu ve světové ekonomice

    OpenAIRE

    Kadlecová, Anna

    2017-01-01

    The diploma thesis deals with the current position of tourism in the global economy. The work focuses on the regional layout of international tourism in terms of international arrivals, international tourism receipts and international tourism expenses. An emphasis is also put on the economic importance of tourism, mainly in relation to GDP, employment, price stability and balance of payment. The thesis is also focused on current issues in the field of international tourism - shared economy, C...

  14. Akademický slovník současné češtiny

    Czech Academy of Sciences Publication Activity Database

    Kochová, Pavla; Opavská, Zdeňka

    2016-01-01

    Roč. 99, č. 2 (2016), s. 57-83 ISSN 0027-8203 R&D Projects: GA MK DF13P01OVV011 Keywords : dictionary -making principles * lexicography * dictionary macrostructure * dictionary microstructure * monolingual dictionary Subject RIV: AI - Linguistics

  15. Liberalismus a jeho odůvodnění v současné politické filosofii

    OpenAIRE

    Cíbik, Matej

    2015-01-01

    This thesis attempts to answer one basic question: what we can philosophically say to justify liberalism as a mode of political existence of society. It is divided into three parts. In the first one, I critically survey two popular answers to this question, employing the concepts of self- ownership and value pluralism respectively. I argue that both of them are inadequate and unsatisfactory, mostly because they operate with a conception of person that is too thin for the justificatory task. I...

  16. Problematika současné role otce v rodině aneb krize identity otcovství

    OpenAIRE

    ŠVEHLOVÁ, Zdeňka

    2009-01-01

    The work deals with position of father in the modern-day family. The dominant position of father in family was lost within the empancipation of women inside the society. There become the system of patriarchy. The modern father has lost his position as a breadwinner of family, becouse of women try to assert at labour market too. The modern father has to find the new identity. He falls into split between traditional and modern position of father. In the work there is described the position of f...

  17. Safety and quality management for radiotherapy treatments - ASN guide nr 5 - Index 1 - Release of the 10/04/2009

    International Nuclear Information System (INIS)

    2009-01-01

    This guide aims at proposing a framework for the safety and quality management for radiotherapy treatments. It addresses the general requirements for the quality management system (general requirements and requirements related to documentation), the management responsibility, the resource management (human and hardware resources), the preparation and performance of activities allowing the taking into care of a patient from his first consultation to the post-treatment follow-up, the assessment, analysis and improvement of the quality management system

  18. Activation of an Asp-124→Asn mutant of haloalkane dehalogenase by hydrolytic deamidation of asparagine

    NARCIS (Netherlands)

    Pries, Frens; Kingma, Jacob; JANSSEN, Dick B

    1995-01-01

    Haloalkane dehalogenase hydrolyses various 1-halon-alkanes to the corresponding alcohols by covalent catalysis with formation of an alkyl-enzyme intermediate. The carboxylate function of the nucleophilic aspartate (Asp-124) that displaces the halogen during formation of the intermediate was changed

  19. Dopady dočasných změn valorizace důchodů

    Czech Academy of Sciences Publication Activity Database

    Janský, Petr

    -, č. 3 (2014), s. 67-78 ISSN 1212-415X Institutional support: RVO:67985998 Keywords : pension indexation * impact evaluation * Czech Republic Subject RIV: AH - Economics http://www.slu.cz/opf/cz/informace/acta-academica-karviniensia/casopisy-aak/aak-rocnik-2014/docs-3-2014/Jansky.pdf

  20. Problém Barák: Neruda z pohledu současné stylometrie

    Czech Academy of Sciences Publication Activity Database

    Plecháč, Petr; Flaišman, Jiří

    2017-01-01

    Roč. 65, č. 5 (2017), s. 743-769 ISSN 0009-0468 R&D Projects: GA ČR(CZ) GA14-31160S Institutional support: RVO:68378068 Keywords : stylometry * authorship attribution * textual criticism * Barák, Josef * Neruda, Jan Subject RIV: AJ - Letters, Mass-media, Audiovision OBOR OECD: Specific literatures

  1. Specifika současné ruské diskuse o Sovětském svazu

    Directory of Open Access Journals (Sweden)

    Zdeněk Bělonožník

    2014-06-01

    Full Text Available The aim of the article is to introduce contemporary Russian discussion on the USSR and Russia in broader political and publicist context. Both positive and negative interpretations of the Russian/Soviet history will be presented. The text does not pretend to provide exhaustive list of the particular “schools” and “movements” nor does it offer historical dynamics or institutional background of the discussion. The author rather intends to single out certain basic schemes and arguments that circulate in the discussions, place them in broader frames and anticipate their potential political consequences. Particularly, the text concentrates on various versions of the patriotic thinking that has been receiving broad popularity in today Russia. As the author is convinced, due familiarity with the contemporary Russian debate may help to better understand Russian internal as well as foreign policy nowadays: as it becomes clear, rise of patriotism in academia, society and politics are inseparable phenomena. Secondly, some of the arguments promoted by the contemporary Russian authors may enrich Western (non-Russian sovietology and debate on socialist experiments as such. Last but not least, both content and form of the Russian academic discussion convincingly point at cultural conditionality of social and historical sciences. To some extent the discussion reminds perpetual Russian debate on national identity; cardinally new context in which it takes place however justifies attention paid to it.

  2. Pracovní migrace a remitence. Současné trendy v době ekonomické krize

    Czech Academy of Sciences Publication Activity Database

    Stojanov, Robert; Strielkowski, Wadim; Drbohlav, D.

    2011-01-01

    Roč. 116, č. 4 (2011), s. 375-400 ISSN 1212-0014 R&D Projects: GA MŠk(CZ) ED1.1.00/02.0073 Institutional research plan: CEZ:AV0Z60870520 Keywords : international migration * remittances * economic crisis * imigration surplus Subject RIV: AO - Sociology, Demography Impact factor: 1.021, year: 2011

  3. Feast/famine regulatory proteins (FFRPs): Escherichia coli Lrp, AsnC and related archaeal transcription factors.

    Science.gov (United States)

    Yokoyama, Katsushi; Ishijima, Sanae A; Clowney, Lester; Koike, Hideaki; Aramaki, Hironori; Tanaka, Chikako; Makino, Kozo; Suzuki, Masashi

    2006-01-01

    Feast/famine regulatory proteins comprise a diverse family of transcription factors, which have been referred to in various individual identifications, including Escherichia coli leucine-responsive regulatory protein and asparagine synthase C gene product. A full length feast/famine regulatory protein consists of the N-terminal DNA-binding domain and the C-domain, which is involved in dimerization and further assembly, thereby producing, for example, a disc or a chromatin-like cylinder. Various ligands of the size of amino acids bind at the interface between feast/famine regulatory protein dimers, thereby altering their assembly forms. Also, the combination of feast/famine regulatory protein subunits forming the same assembly is altered. In this way, a small number of feast/famine regulatory proteins are able to regulate a large number of genes in response to various environmental changes. Because feast/famine regulatory proteins are shared by archaea and eubacteria, the genome-wide regulation by feast/famine regulatory proteins is traceable back to their common ancestor, being the prototype of highly differentiated transcription regulatory mechanisms found in organisms nowadays.

  4. Obraz současné ženy v moderní egyptské próze

    OpenAIRE

    Godiveau, Eliška

    2014-01-01

    The thesis examines the image of the modern Egyptian woman in the prose narrative of four contemporary women writers of Egypt. They are Hala El Badry, Salwa Bakr, Mona Prince and Miral al-Tahawy. Based on the interpretation and analysis of six selected literary texts this paper will aim at uncovering the authors' view on the woman of today's Egypt. The thesis will try to answer its research question, considering the historical development of woman's role and standing in Egyptian society, as w...

  5. Hodnotový svět současné mládeže

    OpenAIRE

    TOMÁNKOVÁ, Barbora

    2015-01-01

    This bachelor thesis deals with the issue of values, particularlywiththeviewof15-30 yearsoldyouthauthority questions. The theoretical part explains concepts such as youth, value, value systems and value orientation. It also focuses on family influence, the impact of school, and peer influence in current youth value systems.Furthermore, the theoretical part examines media and social networks, their influence on current young generation, and the role they play in youth´s lives. The practical pa...

  6. Kongres IFAC v Praze a některé současné problémy automatizace

    Czech Academy of Sciences Publication Activity Database

    Klán, Petr

    2005-01-01

    Roč. 11, č. 3 (2005), s. 86-88 ISSN 1210-9592 Institutional research plan: CEZ:AV0Z10300504 Keywords : IFAC Congress * modern automation * solved problems Subject RIV: BD - Theory of Information http://www.odbornecasopisy.cz/index.php?id_document=30405

  7. Vývoj techniky a taktiky tenisové hry, současné didaktické metody

    OpenAIRE

    Balík, Radek

    2011-01-01

    Title: The Development of Techniques and Tactics of Tennis, including Current Teaching Methods Summary: This bachelor thesis deals with the historical facts of tennis, charting the development of rackets, balls, and surfaces. Besides a brief description of the rules of tennis along with appropriate recommendations for beginners, the thesis covers the development of tennis techniques and tactics. In addition, previous training methods are compared with those of today and their regularities are...

  8. Současné modely likvidních finančních trhů

    OpenAIRE

    Grosu, Iulia

    2012-01-01

    The aim of this paper is to provide a comprehensive overview of selected current models of liquid financial markets, namely to explain their basic principles, assess their strengths and deficiencies and compare them with each other. The thesis is divided into six chapters. The first five chapters focus on the theoretical description of five different models, including their assumptions, the resulting consequences and, where possible, their mathematical formulation. The particular chapters als...

  9. Nuclear energy: what scenarios for the future?; Nucleaire: quels scenarios pour le futur?

    Energy Technology Data Exchange (ETDEWEB)

    Chatelier, Michel; Criqui, Patrick; Heuer, Daniel; Huet, Sylvestre

    2012-01-20

    Because of its energetic, environmental, economical, social, safety, political, and even ideological aspects, the nuclear energy is a major society stake. It is a technical and complex topic as well which merits a democratic, well argued and transparent debate. This book supplies to the reader all the necessary information for a thorough analysis of this much disputed energy source without any bias: why France is one of the most nuclearized country in the world? Can we get out of nuclear energy? How and at what price? Wastes and safety: what can we expect (or not) from the next generations of reactors? Should we have a referendum? In this book, two researchers of the nuclear domain, an economist and a journalist invite us to consider the problem from all angles. (J.S.)

  10. Elecnuc. Nuclear power plants worldwide; Elecnuc. Les centrales nucleaires dans le monde

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-07-01

    This small folder presents a digest of some useful information concerning the nuclear power plants worldwide and the situation of nuclear industry at the end of 1997: power production of nuclear origin, distribution of reactor types, number of installed units, evolution and prediction of reactor orders, connections to the grid and decommissioning, worldwide development of nuclear power, evolution of power production of nuclear origin, the installed power per reactor type, market shares and exports of the main nuclear engineering companies, power plants constructions and orders situation, evolution of reactors performances during the last 10 years, know-how and development of nuclear safety, the remarkable facts of 1997, the future of nuclear power and the energy policy trends. (J.S.)

  11. Perspectives for nuclear energy; Perspectives pour l'energie nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Baugnet, J.-M.; Abderrahim, H.A.; Dekeyser, J.; Meskens, G

    1998-09-01

    In Belgium, approximately 60 percent of the produced electricity is generated by nuclear power. At present, nuclear power production tends to stagnate in Europe and North America but is still growing in Asia. The document gives an overview of the present status and the future energy demand with emphasis on electric power. Different evaluation criteria including factors hindering and factors promoting the expansion of nuclear power as well as requirements of new nuclear power plants are discussed. The extension of the lifetime of existing facilities as well as fuel supply are taken into consideration. A comparative assesment of nuclear power with other energy sources is made. The report concludes with estimating the contribution and the role of nuclear power in future energy demand as well as with an overview of future reactors and research and development programmes.

  12. 1984. Annual progress report of the Institut de Physique Nucleaire at Orsay

    International Nuclear Information System (INIS)

    1985-01-01

    The first part of this report presents the work of the year 1984 of research in the Division of experimental physics of the Institute of Nuclear Physics in Orsay, the activities are conducted in six axes: nuclear structure, high excitation energy nuclear states, heavy ion collision phenomena, intermediate energy nuclear physics, radiochemistry and perinuclear research. The second part presents the studies of the theoretical physics division of the Institute for Nuclear Physics in Orsay in 1984. The different research axes are the following: nuclear physics, intermediate energy nuclear physics, elementary particles. The third part presents a compilation of the work done by the technical groups of the laboratory. The different axes are: operation and development of accelerators, design studies on new superconducting cyclotron project equipment and instrumental projects, technical developments used for specific research [fr

  13. Effets du milieu sur la propagation des neutrinos dans la matiere nucleaire

    CERN Document Server

    Margueron, J

    2001-01-01

    We study the elementary interactions between neutrinos and dense matter in a proroneutron star. Equations of state obtained with different nuclear effective interactions (skyrme, Gogny, relativistic Lagrangians) are first discussed.Then we characterize their stability in spin and isospin. We derive magnetic susceptibilities for all isospin asymmetry values as a function of Landau parameters G^{tau tau'}_0 (where tau, tau' = proton or neutron)We calculate nthe pure neutron matter response functions with and withoutcharge exchange, describing nuclear correlations in both approaches : non-relativistic and relativistic. At the end we calculate neutrino mean free paths for neutral current and charged current reactions.Comparisons between relativistic and non-relativistic approaches allow us to identify relativistic effects in nuclear matter at densities as low as twice the saturation density.RPA correlations make the medium more transparent to neutrinos compared to free Fermi gas.

  14. Institut de Physique Nucleaire d'Orsay. Highlights and achievements 2008-2013

    International Nuclear Information System (INIS)

    2013-01-01

    Activities of the Institute through the 2008-2013 period, have been considerable and a detailed description of all of them would have resulted in a relatively large document. The choice was then made to only describe a selection of highlights from the activities of the different groups during the last 5 years. This concerns the five main scientific topics of the institute that are: 1- Nuclear Structure and Dynamics: The highlights described in this section concern the activities of two different research groups 'NESTER' and 'NIM'; 2 - Hadrons and Hadronic Matter: This section concerns the three teams involved in the CLASS collaboration at JLab, the HADES collaboration at GSI and the ALICE collaboration at LHC. All three are part of the group 'PHEN'; 3- Physics and Chemistry of Nuclear Energy: This section covers, on one hand, activities related to Nuclear Data and Simulations of novel option for nuclear energy production within the group 'PACS' and, on the other hand, all the activities that are performed within the 'RC (Radio-chemistry group)'; 4- Astrophysics: This section concerns nuclear astrophysics research activity at the group 'NESTER', the astro-chemistry activity at the 'NIM' group and the astro-particle activity within the 'AUGER' collaboration in the group 'PHEN'; 5 - Theory: This activity concerns mainly the 'Theory' group. Beside these five scientific topics a multidisciplinary activity based mainly on the use of accelerated nanoparticles with the TANDEM accelerator at ALTO is also described. Two additional sections are devoted in the document to summarize the activities related to: 1 -Accelerator physics and technology; 2 - Detector technology, instrumentation and data acquisition and processing. A separate paragraph gives a status report and highlights from the main facilities in the Institute such as ALTO, SUPRATECH and CACAO. The activities on 'Dosimetry' in one hand and on 'Safety and Radiation Protection' on the other hand as well as an overview of the activities within the 'Communication' group are summarized in separate paragraphs. A short paragraph is also given in order to remind the vital activities for the running and functioning of the institute that are covered by the Administration, Logistics and Infrastructure Division (DALI). A special attention was given these last years for continuous training of the personnel. This is motivated by the importance of keeping and passing over the expertise as well as of helping identifying promotion perspectives for all categories of employees (chapter 14). A self-evaluation is proposed in chapter 15. This self-evaluation is largely based on the conclusions of the evaluation of our activities by the Scientific and Technical Advisory committee of the Institute. For each of the activity reports various information is given such as the dedicated human resources and their evolution during the last 5 years, scientific production in terms of publications, participation to conferences etc

  15. Performances of nuclear installations in the world; Performances des installations nucleaires dans le monde

    Energy Technology Data Exchange (ETDEWEB)

    Pate, Z.T. [World Association of Nuclear Operators (WANO), 75 - Paris (France)

    1999-01-01

    During the last years the operators of nuclear power plants in the world, have realized numerous improvements. This success is imputable to several factors, especially an important data exchange. The Chernobyl accident, in 1986, provoked the creation of the World Association of Nuclear Operators (W.A.N.O.). It allowed to exchange information and to develop cooperation in order to go beyond cultural barriers, linguistics and policies. Then, operators in the world have brought important improvements in matter of safety, reliability. (N.C.)

  16. Institut National des Sciences et Techniques Nucleaires. From academic to vocational: specificity and vision

    Energy Technology Data Exchange (ETDEWEB)

    Turpin, Laurent [Institut National des Sciences et Techniques Nucleaires - INSTN, CEA-Saclay (France)

    2008-07-01

    - What is INSTN?: Teaching and training service of CEA; Capability of awarding degrees; Stand-alone: only specialty degrees; Partnership with universities and Engineer schools: master degrees; Professional training operator for CEA and for SMEs. - Corner stones for the next future (5-10 years): increasing the capability in nuclear training (Nuclear skills for nuclear engineers (reactor physics,...), factor 3-4, Nuclear skills for non-nuclear engineers (civil works, project management,...), All stakeholders have to do more (Academics on basic knowledge (have to prepare to a wide range of positions), Specialty institutes on specialized knowledge (before the job and on the job), Internal programs on proprietary programs), optimizing the resources (No false hope: more training means higher costs but does not mean nuclear companies will lay golden eggs; Availability of teaching resource and capability of internship tutoring could be bottlenecks; Trained/graduate production must match actual human resources needs). - A strategy for INSTN: Academic partnerships, to implement nuclear modules within training programs; With companies, a stakeholder-shareholder joint venture model for postgraduate training; Open to European and offshore cooperation.

  17. Which future for the nuclear counter-proliferation?; Quel avenir pour la contre-proliferation nucleaire?

    Energy Technology Data Exchange (ETDEWEB)

    Duval, M

    2004-10-01

    After a recall of the permanent data about proliferation and of the safeguards implemented by the international community, the author demonstrates that proliferation has moved towards Asia where a real 'black market' has been created. Then he analyzes the consequences of this change on the future of nuclear deterrent. Finally, he expresses his nostalgia in front of this drift and worries about the future uselessness of the means devoted to this 'pacifying' strategy. (J.S.)

  18. Probing nuclear structure with nucleons; Sonder la structure nucleaire avec des nucleons

    Energy Technology Data Exchange (ETDEWEB)

    Bauge, E. [CEA Bruyeres-le-Chatel, Service de Physique Nucl aire, 91 (France)

    2007-07-01

    The goal of this lecture is to show how nucleon scattering can be used to probe the structure of target nuclei, and how nucleon scattering observables can be interpreted in terms of nuclear structure using microscopic optical potentials. After a brief overview of the specificities of nucleon-nucleus scattering, and a quick reminder on scattering theory, the main part of this lecture is devoted to the construction of optical potentials in which the target nuclei structure information is folded with an effective interaction. Several examples of such microscopic optical model potentials are given. (author)

  19. Fatigue damage of nuclear facilities; Endommagement par fatigue des installations nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    The conference on the fatigue damage of nuclear facilities, organized by the SFEN (french society of nuclear energy), took place at Paris the 23. of november 2000. Eleven papers were presented, showing the state of the art and the research programs in the domain of the sizing rules, safety, installations damage, examination and maintenance. (A.L.B.)

  20. Prospective analysis. Nuclear deterrence in 2030; Essai de prospective. La dissuasion nucleaire en 2030

    Energy Technology Data Exchange (ETDEWEB)

    Tertrais, B

    2006-12-15

    This study is a prospective analysis of the long-term future of nuclear weapons, and particularly the future of French nuclear deterrence after 2015. The selected time period is 2025-2030. The principal objective is to reflect on what the nuclear world might look like during the first part of the 21 st century, beyond the modernization decisions already planned or envisaged, and to draw conclusions for the future of the French deterrent. (author)

  1. The nuclear industry is looking for its technicians; Le nucleaire cherche ses techniciens

    Energy Technology Data Exchange (ETDEWEB)

    Dumas, A

    2010-03-15

    With massive retirements planned up to 2015, the French nuclear industry wishes to recruit technicians for the operation and maintenance of its power plants. The French nuclear park represents 19 power plants with 58 reactors. The nuclear industry personnel represents 19000 people at EdF and about 20000 people from about 600 different service provider companies. Technician's salary ranges from 1500 to 2800 euros for experienced people, bonus not included. Before being operational, the French nuclear technicians have to follow a long training period in one of the 20 specialized and certified training centres. However, the training demand is so important that the industry suffers from a lack of instructors as well. (J.S.)

  2. The nuclear power cycle; Le cycle de l'energie nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    Fifty years after the first nuclear reactor come on-line, nuclear power is fourth among the world's primary energy sources, after oil, coal and gas. In 2002, there were 441 reactors in operation worldwide. The United States led the world with 104 reactors and an installed capacity of 100,000 MWe, or more than one fourth of global capacity. Electricity from nuclear energy represents 78% of the production in France, 57% in Belgium, 46% in Sweden, 40% in Switzerland, 39% in South Korea, 34% in Japan, 30% in Germany, 30% in Finland, 26% in Spain, 22% in Great Britain, 20% in the United States and 16% in Russia. Worldwide, 32 reactors are under construction, including 21 in Asia. This information document presents the Areva activities in the nuclear power cycle: the nuclear fuel, the nuclear reactors, the spent fuel reprocessing and recycling and nuclear cleanup and dismantling. (A.L.B.)

  3. Nuclear energy for the 21. century; Energie nucleaire pour le 21. siecle

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-03-15

    This document gathers 5 introductory papers to this conference about nuclear energy for the 21. century: the French energy policy during the last 30 years (situation of France with respect to the energy supply and demand, main trends of the French energy policy, future of the French nuclear policy); presentation of IAEA (technology transfer, nuclear safety, non-proliferation policy, structure and financial resources, council of governors, general conference, secretariat); nuclear power and sustainable development; promoting safety at nuclear facilities (promoting safety, basics of safety, safety at the design stage, risk management, regulatory control and efficiency of the regulation organization, role of IAEA); nuclear energy today (contribution to sustainable development, safety, best solution for the management of radioactive wastes, future of nuclear energy). (J.S.)

  4. Overview of the US nuclear industry; Le panorama nucleaire aux Etats-Unis

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-04-01

    This article makes a brief summary of the nuclear industry activity in the USA: present day nuclear park availability, next generation of nuclear reactors (Generation IV), nuclear power 2010 initiative (early site permit, design certification, construction and operating licence), fuel cycle (enrichment, USEC company, USA-Russia highly-enriched uranium (HEU) agreement, SILEX and centrifugation separation processes, Louisiana Energy Services (LES) consortium and the National Enrichment Facility project, waste management, problem of storage and disposal sites for low-level radioactive wastes, trans-uranian wastes, and the Yucca Mountain project (Nevada) of disposal site for high level radioactive wastes). (J.S.)

  5. Comprehensive survey of the Russian nuclear industry; Le panorama nucleaire russe

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-03-01

    This document presents the organization of nuclear activities in the Russian federation: Minatom and its replacement by the federal agency of atomic energy, personnel, nuclear power plants (VVER, RBMK, fast neutron and mixed reactors), availability and power production, export of activities (construction of nuclear power plants in Slovakia, Iran, China, India, project in Viet Nam), expansion of the nuclear power plants park (improvement of plants safety, increase of service life), completion of uncompleted plants, the construction of which was stopped after the Chernobyl accident and the reorganization of the former-USSR, construction of new generation power plants (VVER-640, -1000 and -1500), fuel cycle facilities (geographical distribution, production of natural uranium, conversion and enrichment), fuel fabrication, reprocessing processes and spent fuel storage, management of radioactive wastes (leasing), R and D activities (organizations and institutes), research programs of the international scientific and technical center, nuclear safety authority (Gosatomnadzor - GAN). (J.S.)

  6. The radioactive wastes management; Le dossier: les dechets nucleaires et leur gestion

    Energy Technology Data Exchange (ETDEWEB)

    Rigny, P. [Actualite Chimique, 75 - Paris (France); Bonin, B. [CEA Saclay, Dir. de l' Energie Nucleaire, 91 - Gif sur Yvette (France); Gras, J.M. [Electricite de France (EDF-RD), Recherche et Developpement, 78 - Chatou (France)

    2010-11-15

    The different types of radioactive waste are presented in this paper in the frame of the official categories which take into account their dangerousness and the lifetimes of their radioactivity. It is indicated how the less dangerous of them are handled in France. The ways of protecting the environment from the more dangerous ones (high activity and long lifetimes) are object of studies. Scientific questions, in the field of chemistry and physical chemistry, related to the implementation of deep underground repository facilities with full respect of nuclear safety are presented. (authors)

  7. Nuclear wastes: status and perspectives; Les Dechets nucleaires: etat des lieux et perspectives

    Energy Technology Data Exchange (ETDEWEB)

    Barre, B.; Bazile, F.; Bonin, B.; Marvy, A.; Ouzounian, G.; Wizsenfeld, B.

    2011-07-01

    Radioactive wastes are considered by the large public as a problem which mortgages the future of nuclear industry. Today, the main principles of radioactive wastes management are defined: separation, conditioning, storage and disposal are the main elements of a strategy allowing to protect the man and the environment from the impacts of the inevitable ultimate wastes. In a period of debate concerning the future of these wastes, this book aims at supplying to the public the elements which will allow him to build his own opinion about this hot topic. (J.S.)

  8. Nuclear non proliferation and disarmament; Non-proliferation nucleaire et desarmement

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    In the framework of the publication of a document on the ''weapons mastership, disarmament and non proliferation: the french action'', by the ministry of Foreign Affairs and the ministry of Defense, the French Documentation organization presents a whole document. This document describes and details the following topics: the conference on the treaty of non proliferation of nuclear weapons, the France, Usa and Non Governmental Organizations position, the threats of the proliferation, the french actions towards the disarmament, the disarmament in the world, a chronology and some bibliographic resources. (A.L.B.)

  9. Phasing out nuclear, a credible scenario; Sortir du nucleaire, un scenario credible

    Energy Technology Data Exchange (ETDEWEB)

    Chatelain, C.; Mulot, R.; Chauveau, L.; Hait, J.F.

    2011-08-15

    Based on data from different companies, institutions and associations involved in nuclear energy (either in its production or in its critic), this article comments the possible energy savings (50 to 64%) that may be reached in the different sectors, and more particularly in the building sector and in electrical equipment. It discusses the potential production from solar, wind and biogas energy. It notices that phasing out nuclear is possible by 2030-2050, but would entail an increase of electricity prices. The German approach is presented. An article comments the anger of Fukushima Japanese farmers and evokes the slow building up of a solidarity network between France and Japan. A last article comments the authorization given to a further exploitation of the Fessenheim nuclear power plant (ten more years)

  10. Nuclear energy: obstacles and promises; L'energie nucleaire: obstacles et promesses

    Energy Technology Data Exchange (ETDEWEB)

    Bacher, P

    2003-07-01

    Nuclear energy has distinctive merits (sustainable resources, low costs, no greenhouse gases) but its development must overcome serious hurdles (fear of accidents, radio-phobia, waste management). The large unit size of present-day reactors is compatible only with large electrical grids, and involves a high capital cost. Taking into account these different factors, the paper outlines how nuclear energy may contribute to the reduction of greenhouse gases, and which are the most promising developments. (author)

  11. Information report nuclear energy in Europe; Rapport d'information energie nucleaire en Europe

    Energy Technology Data Exchange (ETDEWEB)

    Montesquiou, A de

    2002-07-01

    This report takes stock on the nuclear energy situation in Europe. The European Union with more than 40% of the nuclear power capacity in the world, is already confronted with the nuclear energy place and stakes in the future energy policy. The report si presented in two main parts. The first part, ''the assets and the weaknesses of the nuclear energy'', deals with the economical aspects which historically based the choice of the nuclear energy and the induced impacts on the environment. The competitiveness of the nuclear energy but also the wastes management problem are discussed. The second part, ''the diplomatic and juridical framework of the nuclear energy development'', details and presents the limits of the EURATOM treaty. (A.L.B.)

  12. The nuclear energy and the greenhouse effect; Le nucleaire et l'effet de serre

    Energy Technology Data Exchange (ETDEWEB)

    Marignac, Y.; Legrand, V. [Wise, 75 - Paris (France)

    2003-10-15

    This article tackles the problem of greenhouse effect and asks the question to know if the development of nuclear energy constitutes the answer to this problem. It appears that the nuclear energy cannot solve in itself the problem of greenhouse effect. Others actions on energy demand, on transport ( that is a big consumer of petroleum and that represents 25% of world emissions) have to studied and need a real policy will. (N.C.)

  13. Should we be scared of nuclear energy?; Faut-il avoir peur du nucleaire?

    Energy Technology Data Exchange (ETDEWEB)

    Allegre,