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Sample records for northern sweden pedigree

  1. A novel stroke locus identified in a northern Sweden pedigree

    DEFF Research Database (Denmark)

    Janunger, T.; Nilsson-Ardnor, S.; Wiklund, P.-G.

    2009-01-01

    OBJECTIVES: The population of northern Sweden is characterized by reduced genetic diversity and a high incidence of stroke. We sought to reduce genetic variation further, using genealogic analysis in a set of nuclear families affected by stroke, and we subsequently performed a genome-wide scan...... to identify novel stroke susceptibility loci. METHODS: Through genealogy, 7 nuclear families with a common ancestor, connected over 8 generations, were identified. A genome-wide scan using 449 microsatellite markers was performed with subsequent haplotype analyses. RESULTS: A maximum allele-sharing lod score...... of 4.81 on chromosome 9q31-q33 was detected. Haplotype analysis identified a common 2.2-megabase interval in the chromosomal region in 4 of the nuclear families, where an overrepresentation of intracerebral hemorrhage was observed. CONCLUSIONS: We have identified a novel susceptibility locus for stroke...

  2. Cult sites in northern Sweden

    Directory of Open Access Journals (Sweden)

    Stefan Brink

    1990-01-01

    Full Text Available The pagan cult in northern Sweden, i.e, Norrland, has for some decades been a neglected chapter in our history, a situation which unfortunately applies to Sweden as a whole, at least where onomastics are concerned. The aim is thus to deliver an overview of the evidence that we have of pre-Christian religious activities in these northern parts — in this aspect, onomastic material is nearly almost all we have got — and some general remarks about the conversion to the new Christian religion. The area of investigation is what in the (Swedish medieval period was known as Norrland. In other words, the part of Sweden considered here is modern Central Norrland. With our state of knowledge of today it is not so easy to pick out the place-names that have denoted some kind of pagan cult activity. The place-name material can be divided into: 1. Theoforic place-names 2. place-names denoting the site of a pagan cult, which do not however contain theoforic elements 3. place-names with a possible pagan cultic element.

  3. Space education in Kiruna, Northern Sweden

    Directory of Open Access Journals (Sweden)

    I. Sandahl

    2005-01-01

    Full Text Available The town of Kiruna in the north of Sweden has a concentration of space activities and space research with, for example, the Swedish Institute of Space Physics, Esrange, the ESA Salmijärvi satellite station, and EISCAT (European Incoherent Scatter Radar Scientific Association. The Department of Space Science is a joint department between the two most northern universities in Sweden, Luleå University of Technology and Umeå University in collaboration with the Swedish Institute of Space Physics. It offers a range of education programmes in the space field. There are bachelor and master programmes in space engineering, and a bridging programme for students without a science background from secondary school. The Department also contributes to courses for teachers, Ph.D. courses and secondary school level courses. One master´s program and a three week summer course are given entirely in English and welcome international students. Thanks to good cooperation with Esrange students can build and fly experiments on high altitude balloons and sounding rockets and also take a large responsibility for the management of the projects. Close interaction with research and industry is an important part of the education.

  4. Neotectonics in northern Sweden - geological investigations

    International Nuclear Information System (INIS)

    Lagerbaeck, R.; Witschard, F.

    1983-05-01

    Fairly large areas around the formerly known quaternary faults have been air photo interpreted. The fault known as the Parvie fault has been found to extend somewhat further towards the south, thereby crossing the valley of the Stora Lule river. Furthermore, another fault has been discovered in the Lansjaerv region, and thus the faults in this area form a better fit to the regional pattern, with a SSW - NNE trend and a relative uplift of the eastern part. The fault scarps have been leveled photogrammatrically, and reproduced on maps on the scales of 1:50000 and 1:100000, and on overview maps on the scale of 1:250000. The highest leveld scarps somewhat exceed 30 m. The total length of the faults is roughly 300 km. During the air photo interpretation, several landslides have been detected, and it seems evident from their location that there is a causal connection between faults and landslides. It seems evident that the different faults are not simultaneously formed, but created at separate events. Representative samples have been collected, and thin sections of these investigated under the microscope. Often, the bedrock shows signs of older tectonic influence, and it seems that the faults largerly have been released along existing zones of weakness in the bedrock. However, striking exceptions, with fracturing through unaltered rock, have been found in several places. The faults illustrated in the maps below undoubtedly represent the most important signs of late quaternary fault activity in Norrbotten east of the Caledonian mountains. The geographic, and very probably also causal connection between faults and landslides seems obvious in both Finland and Sweden. We need a satisfactory tectonic explanation for the faults. Undoubtedly, the glacial - isostatic forces have a central role. The strike of the faults is approximately perpendicular to the direction of plate motion, and compressive forces have acted at the formation of the faults. (author)

  5. 137Cs in the population of northern Sweden

    International Nuclear Information System (INIS)

    Aagren, G.; Bjoereland, A.; Johansson, Lennart.

    1996-12-01

    The activity of Cs 137 has been studied in several different population groups in northern Sweden after the Chernobyl accident. Special attention has been given to the Saami (Lapp) population from which we have measured a group of volunteers regularly between 1986 and 1990. In 1991 we started a study on randomly chosen groups from the general population and members of the Saami communities from three regions in northern Sweden with different deposition levels. The results from these measurements have shown an effective half-time of Cs whole-body content in the Saami groups of about five years. The measurements in 1996 show decreasing levels of activities in the different population groups with half-times between 4 and 12 years. Another exposed group is breast-fed babies. We have measured the transfer of Cs from mother to baby via the breast milk in 12 cases. The activity in breast milk was measured to be 14% of the activity in the mother (calculated using specific activity - Bq/kg). The corresponding activity in the baby was 90% of the activity in the mother. 13 refs

  6. Knee injuries in skiing. A prospective study from northern Sweden.

    Science.gov (United States)

    Edlund, G; Gedda, S; Hemborg, A

    1980-01-01

    This paper evaluates 420 ski injuries occurring in Northern Sweden in 1977. Our main aim was to correlate knee injuries with types of skiing and to note a change in incidence with evolution of equipment. Fifty-eight lesions (13.8%) affected the knee joint which is about the same frequency as 10 years earlier nor has introduction of high stiff boots in downhill skiing increased incidence of knee injuries. Cross-country and long-distance skiing produced more knee injuries (24.7%) than downhill skiing (11.4%). Cross-country skiers were older and more women in this group sustained knee injuries. The use of non-release type bindings is probably the main reason for this higher incidence but age and different skiing techniques seem to contribute.

  7. Postglacial faulting and paleoseismicity in the Landsjaerv area, northern Sweden

    International Nuclear Information System (INIS)

    Lagerbaeck, R.

    1988-10-01

    Post-glacial fault scarps, up to about 20 m in height and forming a 50 km long fault set with a SSW-NNE orientation, occur in the Lansjaerv area in northern Sweden. By trenching across the fault scarps it has been possible to date fault movement relative to the Quaternary stratigraphy. It is concluded that the fault scarps generally developed as single event movements shortly after the deglaciation about 9000 years ago. At one location there are indications that minor fault movements may have occurred earlier during a previous glaciation but this is uncertain. The fault scarps are, at least partially, developed in strongly fractured and chemically weathered zones of presumed pre-Quaternary age. To judge from the appearance of the bedrock fault scarps, and the deformation of the Quaternary deposits, the faults are reverse and have dips between some 40-50 0 and the vertical. The faulting was co-seismic and earthquakes in the order of M 6.5-7.0, or higher, are inferred from fault dimensions and the distribution of seismically triggered landslides in a wider region. Distortions in different types of sediment, interpreted as caused by the influence of seismic shock, occur frequently in the area. Examples of these are briefly described. (orig.)

  8. Atmospheric mercury in Sweden, Northern Finland and Northern Europe. Results from national monitoring and European research

    Energy Technology Data Exchange (ETDEWEB)

    Waengberg, Ingvar; Munthe, John

    2001-01-01

    Atmospheric mercury concentrations and mercury fluxes measured during the period 1995 to 1999 at the AMAP master station of Pallas, a remote station in Northern Finland, and at Roervik an EMEP station located on the west coast of Sweden are reported. The results are discussed and compared with atmospheric mercury data generated within the EU-project, Mercury over Europe (MOE). Total particulate mercury exhibit a strong south to north gradient with the highest concentrations in the south, near source areas in Central Europe. Mercury in precipitation also exhibits a south to north gradient.

  9. Sustainable railway bridges with higher axle loads:monitoring examples from northern Sweden

    OpenAIRE

    Elfgren, Lennart; Enochsson, Ola; Täljsten, Björn; Paulsson, Björn

    2007-01-01

    Monitoring of several railway bridges has been carried out in northern Sweden in order to increase the allowable axle load. The work is part of a European Integrated Project "Sustainable Bridges - Assessment for Future Traffic Demands and Longer Lives". The paper describes the project and gives some examples of applications. Monitoring of several railway bridges has been carried out in northern Sweden in order to increase the allowable axle load. The work is part of a European Integrated P...

  10. Estimating inbreeding rates in Northern Spotted Owls: insights from pedigrees and spatio-demographic models

    Science.gov (United States)

    The federally-threatened Northern Spotted Owl (Strix occidentalis caurina) has a substantial influence on management of federal lands. Despite decades of investigation, important details about its status and habits remain unknown. In particular, determining the frequency of inbre...

  11. Life Satisfaction among Outbound Students in Northern Sweden

    Science.gov (United States)

    Nilsson, Per A.

    2015-01-01

    The transition from one's home country to a university abroad can be demanding. This study is a follow-up study exploring life satisfaction among outbound students. Outbound students at Umeå University, Sweden, were surveyed before and after experiencing studying abroad. Thus, the students' life satisfaction could be compared after an…

  12. Late quaternary faulting and paleoseismicity in northern Fennoscandia, with particular reference to the Lansjaerv area, northern Sweden

    International Nuclear Information System (INIS)

    Lagerbaeck, R.

    1990-01-01

    Many fault scarps, interpreted as post- or late-glacial in age, occur in northern Sweden and adjacent parts of Finland and Norway. In the Lansjaerv area in northern Sweden attempts have been made to date fault displacement relative to the glacial and postglacial stratigraphy by trenching across some of these fault scarps. It is shown that the faulting occurred soon after the local deglaciation some 9000 years ago. There are no signs of movements since that time. The faulting was obviously associated with violent earthquakes because seismically induced phenomena, dating from the same period as the faulting, are frequently found in the vicinity. Numerous landslides, developed in glacial till, occur in the same region as the faults and different types of seismites (seismically-induced sediment deformation) were found when actively sought for. It is concluded that several earthquakes of high magnitudes occurred in northern Fennoscandia during the vanishing of the inland ice sheet. (author)

  13. Experiences of Facebook among media students in northern Sweden:living in a social media culture

    OpenAIRE

    Juntti-Henriksson, Ann-Kristin

    2013-01-01

    University students enrolled on the “Media and communication program” in northern Sweden have been interviewed regarding their use of social media. By examining the resulting narratives through approaching poststructuralism, the study put emphasis on how the media students think and feel about their use of Facebook. Media students are heavy Facebook users who spend many hours on the social network. As future professional workers in the media industry they have a multidimensional interest in s...

  14. Sweden

    International Nuclear Information System (INIS)

    2011-01-01

    The Swedish nuclear industry is - like in many countries - in a state of rejuvenation. During the coming ten years, 6000 new staff will be employed, which in volume corresponds to the entire present industry. These numbers are based on retirements (easy to estimate), increased needs due to new-build, and to increased mobility of the new staff to be employed (more difficult to estimate). Until now, employment in nuclear power have often lasted very long. We anticipate, however, that the young people that will be recruited will be less prone to stay at the same place for long. Until now, Sweden has never had a dedicated bachelor level nuclear engineering programme. This will, however, change. A new programme will start at Uppsala University in autumn 2010. An existing 3-year bachelor-level mechanics engineering education programme will get a third-year specialization in nuclear engineering. This specialization has been designed to allow students from any technical college or university in Sweden with mechanical or electric engineering in the curriculum. The studies will be in Swedish. Industry is involved both as sponsors and as contributors. The industry educational company (KSU) is closely involved, e.g. with simulator training. The Royal Institute of Technology (KTH), Stockholm, has offered an international MSc in nuclear engineering since 2008. The programme has attracted 10-15 students per year. In addition, students at other programmes participate in some courses, resulting in about 25 students in an average course. Chalmers Institute of Technology, Gothenburg, has started a new nuclear engineering MSc programme in autumn 2009. The programme has equal shares of reactor physics/technology and nuclear chemistry, reflecting the competence profile at Chalmers. This special curriculum is highly appreciated by the Ringhals nuclear power plant nearby, that houses three PWRs, and needs staff with combined reactor physics and nuclear chemistry competence. Uppsala

  15. Uranium in soil, forest litter and living plant material above three uranium mineralizations in Northern Sweden

    International Nuclear Information System (INIS)

    Ek, John

    1982-01-01

    In order to investigate the feasibility of biogeochemical sampling media in uranium exploration, samples from the most common trees and low bushes together with forest litter were collected over the areas of three uranium mineralizations in Northern Sweden and analyzed for uranium. The results were compared with uranium content of the till and its radioactivity. The average uranium content was low for all sample types and considerably lower in the ash of the organic sample types compared to that of the till. No sample type showed any tendency of having higher uranium concentration above mineralizations compared to background areas. These results suggest that, under conditions prevailing in Sweden, the investigated sample types are not suitable for uranium exploration

  16. Incidence of tonsillar cancer in northern Sweden: Impact of human papilloma virus.

    Science.gov (United States)

    Loizou, Christos; Laurell, Göran; Lindquist, David; Öfverman, Charlotte; Stefansson, Kristina; Nylander, Karin; Olofsson, Katarina

    2015-12-01

    The incidence rate of tonsillar cancer is increasing worldwide. The current study identifies a parallel increase in the incidence of tonsillar cancer, human papilloma virus (HPV) and p16 expression among a population from northern Sweden, a sparsely populated area, confirming the strong association between p16 and HPV infection in tonsillar tissue. Data from the Swedish Cancer Registry was assessed to identify cases of tonsillar cancer in the northern territorial area of Sweden. HPV DNA was extracted from paraffin embedded diagnostic biopsies and detected by polymerase chain reaction using general primers Gp5+/6+ and CpI/IIG. Expression of p16 was identified by immunochemistry. Patients were grouped into urban or rural residence categories. A total of 214 cases were identified, comprising 155 (72.4%) men and 59 (27.6%) women, and 65 of these patients, who presented between 2000 and 2012, were analyzed. The overall median age for the analyzed patients was 58 years; 48 (74%) were males (median age, 57.5 years) and 17 (26%) were females (median age, 65 years). Of the 65 specimens, 59 (91%) were positive for HPV, and 62 (95%) expressed p16. The incidence of tonsillar cancer in the cohort demonstrated a 2-fold increase between 1990 and 2013; specifically, a 2.7-fold increase was observed in men whilst the female group exhibited only a small increase. These findings demonstrate a strong association between p16 expression and HPV infection in tonsillar malignancies. The incidence of HPV-positive tonsillar cancer has increased in recent years, even in sparsely populated regions, as demonstrated in northern Sweden.

  17. Separating natural acidity from anthropogenic acidification in the spring flood of northern Sweden

    International Nuclear Information System (INIS)

    Laudon, Hjalmar

    2000-01-01

    Spring flood is an occasion for transient hydrochemical changes that profoundly effect the biodiversity of the aquatic ecosystem. Spring flood is also very susceptible to anthropogenic acidification. Belief that acid deposition is primarily responsible for pH decline during spring flood has been an important factor in the decision to spend close to one billion Swedish crowns to lime surface waters in northern Sweden during the last decade. The objective of this work is to present an operational tool, the Boreal Dilution Model (BDM), for separating and quantifying the anthropogenic and natural contributions to episodic acidification during spring flood episodes in northern Sweden. The limited data requirements of 10-15 stream water samples before and during spring flood make the BDM suitable for widespread use in environmental monitoring programs. This creates a possibility for distinguishing trends and spatial patterns in the human impact as well as natural pH decline. The results from applying the BDM, and a one point 'pBDM' version of the model, in northern Sweden demonstrate that the anthropogenic component associated with spring flood episodes is now generally limited. Instead it is the combination of natural organic acidity and dilution of the buffering capacity that is the major driving mechanism of episodic acidity during spring flood events in the region. While the anthropogenic component of episodic acidification generally contributes 0.1 to 0.3 pH units to the natural pH decline of up to 2.5 pH units, the current regional extent of areas that are severely affected by anthropogenically driven episodes is approximately 6%. Prior to the initiation of the Swedish Environmental Protection Agency's 'Episode Project' the limited spring flood data together with lack of a systematic methodology for determining liming candidates forced the liming authorities to base the remediation strategy in northern Sweden on biological indications. But, since there are more

  18. Distribution of radioactive caesium in the population of northern Sweden 1988-1993

    International Nuclear Information System (INIS)

    Johansson, L.; Wickman, G.; Aagren, G.; Eriksson, A.; Jonsson, H.; Tavelin, B.

    1995-01-01

    During the period from May 1988 until June 1993 the 137 Cs concentration was measured in 751 samples of psoas muscle from selected medico-legal autopsy cases in the northern half of Sweden. In this area the deposition level of 137 Cs from the Chernobyl accident varied from negligible to 100 kBq.m -2 . Northern Sweden is characterised by large boreal forest areas and a sparse population. The rural population often has a high level of subsistence through meat from reindeer, moose and other game, fresh water fish, forest wild berries and mushrooms. From a multiple linear regression performed on the 137 Cs concentration in the 751 measured samples of human muscle, the effective half-time of caesium whole-body content in the population could be assessed as 3.7 years. A slight increase in 137 Cs concentration was observed with the age of the individual and a significant difference between the sexes, the level for men exceeded that for women by 23%. The dose commitment to this population of approximately 900,000 inhabitants from internal radiation due to the Chernobyl debris could, by this model, be estimated at 220 man.Sv which, with the current ICRP lifetime risk estimates, would cause an addition of ten fatal cancer cases. (author)

  19. Traces of medieval migrations in a socially stratified population from Northern Italy. Evidence from uniparental markers and deep-rooted pedigrees.

    Science.gov (United States)

    Boattini, A; Sarno, S; Pedrini, P; Medoro, C; Carta, M; Tucci, S; Ferri, G; Alù, M; Luiselli, D; Pettener, D

    2015-02-01

    Social and cultural factors had a critical role in determining the genetic structure of Europe. Therefore, socially stratified populations may help to focus on specific episodes of European demographic history. In this study, we use uniparental markers to analyse the genetic structure of Partecipanza in San Giovanni in Persiceto (Northern Italy), a peculiar institution whose origins date back to the Middle Ages and whose members form the patrilineal descent of a group of founder families. From a maternal point of view (mtDNA), Partecipanza is genetically homogeneous with the rest of the population. However, we observed a significant differentiation for Y-chromosomes. In addition, by comparing 17 Y-STR profiles with deep-rooted paternal pedigrees, we estimated a Y-STR mutation rate equal to 3.90 * 10(-3) mutations per STR per generation and an average generation duration time of 33.38 years. When we used these values for tentative dating, we estimated 1300-600 years ago for the origins of the Partecipanza. These results, together with a peculiar Y-chromosomal composition and historical evidence, suggest that Germanic populations (Lombards in particular) settled in the area during the Migration Period (400-800 AD, approximately) and may have had an important role in the foundation of this community.

  20. Physical properties and petrologic description of rock samples from an IOCG mineralized area in the northern Fennoscandian Shield, Sweden

    DEFF Research Database (Denmark)

    Sandrin, Alessandro; Edfelt, Å.; Waight, Tod Earle

    2009-01-01

    The Tjårrojåkka Fe-Cu prospect in northern Sweden is considered an example of a Fe-oxide Cu-Au (IOCG) deposit and is hosted in metamorphosed Paleoproterozoic volcanic and intrusive rocks. Rock samples from 24 outcrops were collected for petrophysical analysis (magnetic susceptibility, remanent ma...

  1. Use of radiography in public dental care for children and adolescents in northern Sweden

    DEFF Research Database (Denmark)

    Falk Kieri, Catarina; Twetman, Svante; Stecksén-Blicks, Christina

    2009-01-01

    The primary aims were to investigate the total number of radiographs and the reason for dental radiography in children and adolescents in the Public Dental Health Service. Secondary aims were to study the influence of caries experience and orthodontic treatment on the number of radiographs....... For this retrospective study, 544 adolescents regularly attending three Public Dental Health clinics in the county of Västerbotten, northern Sweden were selected. The number of radiographs exposed each year from 3 to 19 years of age was registered. Information on reason for the radiographic examination was extracted...... from dental records as well as the caries experience at 19 years of age. The attrition rate was 7% due to incomplete data. The total mean number of radiographs exposed was 23+/-6 of which 1+/-2 were extra-oral radiographs. Bitewing radiographs for caries registration constituted 87% of the intra...

  2. Doctors' and nurses' perceptions of a ward-based pharmacist in rural northern Sweden.

    Science.gov (United States)

    Sjölander, Maria; Gustafsson, Maria; Gallego, Gisselle

    2017-08-01

    Background This project is part of the prospective quasi experimental proof-of-concept investigation of clinical pharmacist intervention study to reduce drug-related problems among people admitted to a ward in a rural hospital in northern Sweden. Objective To explore doctors' and nurses' perceptions and expectations of having a ward-based pharmacist providing clinical pharmacy services. Setting Medical ward in a rural hospital in northern Sweden. Method Eighteen face-to-face semi-structured interviews were conducted with a purposive sample of doctors and nurses working on the ward where the clinical pharmacy service was due to be implemented. Semi-structured interviews were digitally recorded, transcribed and analysed using thematic analysis. Main outcome measure Perceptions and expectations of nurses and doctors. Results Doctors and nurses had limited experience of working with pharmacists. Most had a vague idea of what pharmacists can contribute within a ward setting. Participants, mainly nurses, suggested inventory and drug distribution roles, but few were aware of the pharmacists' skills and clinical competence. Different views were expressed on whether the new clinical pharmacy service would have an impact on workload. However, most participants took a positive view of having a ward-based pharmacist. Conclusion This study provided an opportunity to explore doctors' and nurses' expectations of the role of clinical pharmacists before a clinical pharmacy service was implemented. To successfully implement a clinical pharmacy service, roles, clinical competence and responsibilities should be clearly described. Furthermore, it is important to focus on collaborative working relationships between doctors, nurses and pharmacists.

  3. Prevalence and sensitization of atopic allergy and coeliac disease in the Northern Sweden Population Health Study

    Directory of Open Access Journals (Sweden)

    Stefan Enroth

    2013-08-01

    Full Text Available Background. Atopic allergy is effected by a number of environmental exposures, such as dry air and time spent outdoors, but there are few estimates of the prevalence in populations from sub-arctic areas. Objective. To determine the prevalence and severity of symptoms of food, inhalation and skin-related allergens and coeliac disease (CD in the sub-arctic region of Sweden. To study the correlation between self-reported allergy and allergy test results. To estimate the heritability of these estimates. Study design. The study was conducted in Karesuando and Soppero in Northern Sweden as part of the Northern Sweden Population Health Study (n=1,068. We used a questionnaire for self-reported allergy and CD status and measured inhalation-related allergens using Phadiatop, food-related allergens using the F×5 assay and IgA and IgG antibodies against tissue transglutaminase (anti-tTG to indicate prevalence of CD. Results. The prevalence of self-reported allergy was very high, with 42.3% reporting mild to severe allergy. Inhalation-related allergy was reported in 26.7%, food-related allergy in 24.9% and skin-related allergy in 2.4% of the participants. Of inhalation-related allergy, 11.0% reported reactions against fur and 14.6% against pollen/grass. Among food-related reactions, 14.9% reported milk (protein and lactose as the cause. The IgE measurements showed that 18.4% had elevated values for inhalation allergens and 11.7% for food allergens. Self-reported allergies and symptoms were positively correlated (p<0.01 with age- and sex-corrected inhalation allergens. Allergy prevalence was inversely correlated with age and number of hours spent outdoors. High levels of IgA and IgG anti-tTG antibodies, CD-related allergens, were found in 1.4 and 0.6% of participants, respectively. All allergens were found to be significantly (p<3e–10 heritable, with estimated heritabilities ranging from 0.34 (F×5 to 0.65 (IgA. Conclusions. Self-reported allergy

  4. Geomorphic features as indicators of climatic fluctuations in a periglacial environment, northern Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Nyberg, R; Lindh, L [Lund Univ. (SE). Dept. of Physical Geography

    1990-01-01

    Goemorphic responses to climatic fluctuations in the periglacial mountain environment of northern Sweden, especially the Abisko mountains, are discussed. Although the frequency and magnitude of rapid mass movements are related to climatic conditions, the depositional patterns of the processes and the variable availability of source material complicate their use as climatic indicators. Possibly, debris flows and slushflows were frequent during the Little Ice Age, according to lichenometric dating of old deposits. Field observations suggest a fairly high frequency also during the last few decades. Boulder pavements, moraine-like ridges and glacial striae in front of major snowfields indicate these were previously larger and in some cases active as small glaciers perhaps in the cold beginning of the 1900's. During the warm 1920-30's snowpatches and glaciers, as well as permafrost mounds were affected by a general degeneration. Climatic inferences made from the mentioned features are still very crude. Tentatively, it is suggested that they are presently beginning to respond to the cooling trend affecting northern Scandinavia since about 1940. The anticipated impact of a greenhouse warming of the atmosphere has thus so far not been noticeable in this high latitude area. (authors).

  5. Geochemical Prospecting of a Uraniferous Bog Deposit at Masugnsbyn, Northern Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Armands, Goesta

    1961-01-15

    In connection with prospecting for uranium ores in northern Sweden a peat bog, situated 4.5 km NW of Masugnsbyn, Norrbotten, Sweden and showing a remarkable content of uranium, was discovered. Closer investigation of several samples of the peat indicated that the comparatively high content of uranium and radon was connected with the occurrence of radioactive springs in the region. It was found that four different kinds of water were responsible for the supply of radioactive material to the peat, viz: ground water, surface water, spring water and ground water emanating from fractured rock. The spring water - probably a mixture of ground water and water from the fractured rock - contains uranium to the extent of micrograms per litre. The pH is about 7. The uranium content of the water system deriving from the fractured rock is about 200-300 micrograms per litre. The maximum radon content is about 3000 emans. The pH is >7 and the specific conductivity about 150 x 10{sup -6}/Ohm/cm The radioactive peat is characterised by extremely low gamma radioactivity which may be due to the recent emplacement of uranium by spring waters. It is suggested that the peat in question has served as a 'collector' for uranium, rare earth metals etc., since the pH condition - pH about 7 - was favourable to the settling of these elements. The uranium enrichment seems to be due to a transport of Na, Mg and Ca bicarbonates emanating from dolomite deposits or pegmatitic granite dikes in the vicinity of the peat, the bicarbonate waters serving as carriers of the uranium.

  6. Geochemical Prospecting of a Uraniferous Bog Deposit at Masugnsbyn, Northern Sweden

    International Nuclear Information System (INIS)

    Armands, Goesta

    1961-01-01

    In connection with prospecting for uranium ores in northern Sweden a peat bog, situated 4.5 km NW of Masugnsbyn, Norrbotten, Sweden and showing a remarkable content of uranium, was discovered. Closer investigation of several samples of the peat indicated that the comparatively high content of uranium and radon was connected with the occurrence of radioactive springs in the region. It was found that four different kinds of water were responsible for the supply of radioactive material to the peat, viz: ground water, surface water, spring water and ground water emanating from fractured rock. The spring water - probably a mixture of ground water and water from the fractured rock - contains uranium to the extent of micrograms per litre. The pH is about 7. The uranium content of the water system deriving from the fractured rock is about 200-300 micrograms per litre. The maximum radon content is about 3000 emans. The pH is >7 and the specific conductivity about 150 x 10 -6 /Ohm/cm The radioactive peat is characterised by extremely low gamma radioactivity which may be due to the recent emplacement of uranium by spring waters. It is suggested that the peat in question has served as a 'collector' for uranium, rare earth metals etc., since the pH condition - pH about 7 - was favourable to the settling of these elements. The uranium enrichment seems to be due to a transport of Na, Mg and Ca bicarbonates emanating from dolomite deposits or pegmatitic granite dikes in the vicinity of the peat, the bicarbonate waters serving as carriers of the uranium

  7. Cancer incidence in northern Sweden before and after the Chernobyl nuclear power plant accident.

    Science.gov (United States)

    Alinaghizadeh, Hassan; Tondel, Martin; Walinder, Robert

    2014-08-01

    Sweden received about 5 % of the total release of (137)Cs from the Chernobyl nuclear power plant accident in 1986. The distribution of the fallout mainly affected northern Sweden, where some parts of the population could have received an estimated annual effective dose of 1-2 mSv per year. It is disputed whether an increased incidence of cancer can be detected in epidemiological studies after the Chernobyl nuclear power plant accident outside the former Union of Soviet Socialist Republics. In the present paper, a possible exposure-response pattern between deposition of (137)Cs and cancer incidence after the Chernobyl nuclear power plant accident was investigated in the nine northernmost counties of Sweden (2.2 million inhabitants in 1986). The activity of (137)Cs from the fallout maps at 1986 was used as a proxy for the received dose of ionizing radiation. Diagnoses of cancer (ICD-7 code 140-209) from 1980 to 2009 were received from the Swedish Cancer Registry (273,222 cases). Age-adjusted incidence rate ratios, stratified by gender, were calculated with Poisson regression in two closed cohorts of the population in the nine counties 1980 and 1986, respectively. The follow-up periods were 1980-1985 and 1986-2009, respectively. The average surface-weighted deposition of (137)Cs at three geographical levels; county (n = 9), municipality (n = 95) and parish level (n = 612) was applied for the two cohorts to study the pre- and the post-Chernobyl periods separately. To analyze time trends, the age-standardized total cancer incidence was calculated for the general Swedish population and the population in the nine counties. Joinpoint regression was used to compare the average annual percent change in the general population and the study population within each gender. No obvious exposure-response pattern was seen in the age-adjusted total cancer incidence rate ratios. A spurious association between fallout and cancer incidence was present, where areas with the

  8. Cancer incidence in northern Sweden before and after the Chernobyl nuclear power plant accident

    International Nuclear Information System (INIS)

    Alinaghizadeh, Hassan; Tondel, Martin; Walinder, Robert

    2014-01-01

    Sweden received about 5 % of the total release of "1"3"7Cs from the Chernobyl nuclear power plant accident in 1986. The distribution of the fallout mainly affected northern Sweden, where some parts of the population could have received an estimated annual effective dose of 1-2 mSv per year. It is disputed whether an increased incidence of cancer can be detected in epidemiological studies after the Chernobyl nuclear power plant accident outside the former Union of Soviet Socialist Republics. In the present paper, a possible exposure-response pattern between deposition of "1"3"7Cs and cancer incidence after the Chernobyl nuclear power plant accident was investigated in the nine northernmost counties of Sweden (2.2 million inhabitants in 1986). The activity of "1"3"7Cs from the fallout maps at 1986 was used as a proxy for the received dose of ionizing radiation. Diagnoses of cancer (ICD-7 code 140-209) from 1980 to 2009 were received from the Swedish Cancer Registry (273,222 cases). Age-adjusted incidence rate ratios, stratified by gender, were calculated with Poisson regression in two closed cohorts of the population in the nine counties 1980 and 1986, respectively. The follow-up periods were 1980-1985 and 1986-2009, respectively. The average surface-weighted deposition of "1"3"7Cs at three geographical levels; county (n = 9), municipality (n = 95) and parish level (n = 612) was applied for the two cohorts to study the pre- and the post-Chernobyl periods separately. To analyze time trends, the age-standardized total cancer incidence was calculated for the general Swedish population and the population in the nine counties. Joinpoint regression was used to compare the average annual percent change in the general population and the study population within each gender. No obvious exposure-response pattern was seen in the age-adjusted total cancer incidence rate ratios. A spurious association between fallout and cancer incidence was present, where areas with the lowest

  9. Cancer incidence in northern Sweden before and after the Chernobyl nuclear power plant accident

    Energy Technology Data Exchange (ETDEWEB)

    Alinaghizadeh, Hassan; Tondel, Martin; Walinder, Robert [Uppsala University, Occupational and Environmental Medicine, Department of Medical Sciences, Uppsala (Sweden)

    2014-08-15

    Sweden received about 5 % of the total release of {sup 137}Cs from the Chernobyl nuclear power plant accident in 1986. The distribution of the fallout mainly affected northern Sweden, where some parts of the population could have received an estimated annual effective dose of 1-2 mSv per year. It is disputed whether an increased incidence of cancer can be detected in epidemiological studies after the Chernobyl nuclear power plant accident outside the former Union of Soviet Socialist Republics. In the present paper, a possible exposure-response pattern between deposition of {sup 137}Cs and cancer incidence after the Chernobyl nuclear power plant accident was investigated in the nine northernmost counties of Sweden (2.2 million inhabitants in 1986). The activity of {sup 137}Cs from the fallout maps at 1986 was used as a proxy for the received dose of ionizing radiation. Diagnoses of cancer (ICD-7 code 140-209) from 1980 to 2009 were received from the Swedish Cancer Registry (273,222 cases). Age-adjusted incidence rate ratios, stratified by gender, were calculated with Poisson regression in two closed cohorts of the population in the nine counties 1980 and 1986, respectively. The follow-up periods were 1980-1985 and 1986-2009, respectively. The average surface-weighted deposition of {sup 137}Cs at three geographical levels; county (n = 9), municipality (n = 95) and parish level (n = 612) was applied for the two cohorts to study the pre- and the post-Chernobyl periods separately. To analyze time trends, the age-standardized total cancer incidence was calculated for the general Swedish population and the population in the nine counties. Joinpoint regression was used to compare the average annual percent change in the general population and the study population within each gender. No obvious exposure-response pattern was seen in the age-adjusted total cancer incidence rate ratios. A spurious association between fallout and cancer incidence was present, where areas with

  10. Oxidative stress in pied flycatcher (Ficedula hypoleuca) nestlings from metal contaminated environments in northern Sweden

    International Nuclear Information System (INIS)

    Berglund, A.M.M.; Sturve, J.; Foerlin, L.; Nyholm, N.E.I.

    2007-01-01

    Metals have been shown to induce oxidative stress in animals. One of the most metal polluted terrestrial environments in Sweden is the surroundings of a sulfide ore smelter plant located in the northern part of the country. Pied flycatcher nestlings (Ficedula hypoleuca) that grew up close to the industry had accumulated amounts of arsenic, cadmium, mercury, lead, iron and zinc in their liver tissue. The aim of this study was to investigate if pied flycatcher nestlings in the pollution gradient of the industry were affected by oxidative stress using antioxidant molecules and enzyme activities. The antioxidant assays were also evaluated in search for useful biomarkers in pied flycatchers. This study indicated that nestlings in metal contaminated areas showed signs of oxidative stress evidenced by up regulated hepatic antioxidant defense given as increased glutathione reductase (GR) and catalase (CAT) activities and slightly but not significantly elevated lipid peroxidation and glutathione-S-transferase (GST) activities. Stepwise linear regression indicated that lipid peroxidation and CAT activities were influenced mostly by iron, but iron and lead influenced the CAT activity to a higher degree. Positive relationships were found between GST and lead as well as GR activities and cadmium. We conclude that GR, CAT, GST activities and lipid peroxidation levels may function as useful biomarkers for oxidative stress in free-living pied flycatcher nestlings exposed to metal contaminated environments

  11. Change of lifestyle habits - Motivation and ability reported by pregnant women in northern Sweden.

    Science.gov (United States)

    Lindqvist, Maria; Lindkvist, Marie; Eurenius, Eva; Persson, Margareta; Mogren, Ingrid

    2017-10-01

    Pregnant women are generally more motivated to change their lifestyle habits compared with non-pregnant women. However, the ability to change these habits depends on the motivation to change. This study describes pregnant women's self-reported motivation and ability to change lifestyle habits and their relation to body mass index (BMI), self-rated health, educational level and country of origin. This cross-sectional study combined data from the Maternal Health Care Register in Västerbotten (MHCR-VB) and the Salut Programme Register (Salut-R). Data were collected from 3,868 pregnant residents in Västerbotten County (northern Sweden) between 2011 and 2012. Chi-square test, two independent samples t-test and univariate and multivariate logistic regression were performed. Most of the pregnant women (61.3%) were satisfied with their self-reported lifestyle habits irrespective of BMI, self-rated health, educational level, and country of origin. Many reported that they wanted to increase their physical activity, improve their dietary habits, and reduce their weight. In general, they estimated their ability to change their lifestyle habits as equal to their motivation of change. Women who reported a large or very large motivation to change their lifestyle habits were characterized by higher BMI and higher educational level. Most of the participating pregnant women were satisfied with their lifestyle habits, although they reported being further motivated to change some of them. Health care professionals encountering fertile and pregnant women may have a unique opportunity to support and promote lifestyle changes, taking into account women's motivation for change. Future research should focus on factors that motivate pregnant women to change their lifestyle, explore barriers for change of lifestyle and how support best may be provided to pregnant women. In addition, studies on lifestyle and motivation for lifestyle change from non-Nordic countries are called for. Copyright

  12. Awareness of sunburn in childhood, use of sunbeds and change of moles in Denmark, Northern Ireland, Norway and Sweden.

    Science.gov (United States)

    Hajdarevic, Senada; Hvidberg, Line; Lin, Yulan; Donnelly, Conan; Gavin, Anna; Lagerlund, Magdalena; Pedersen, Anette F; Rasmussen, Birgit H; Runesdotter, Sara; Vedsted, Peter; Tishelman, Carol

    2016-02-01

    Malignant melanoma (MM) is increasing rapidly in Northern Europe. To reduce incidence and mortality through earlier diagnosis, public awareness of MM is important. Thus, we aim to examine awareness of risk factors and a symptom of MM, and how awareness varies by country and socio-demographic factors in Denmark, Northern Ireland (NI), Norway and Sweden. Population-based telephone interviews using the 'Awareness and Beliefs about Cancer' measure were conducted in 2011 among 8355 adults ≥50 years as part of the International Cancer Benchmarking Partnership Module 2. Prevalence ratios (PRs) with 95% confidence intervals were calculated. In these four countries, lowest awareness was found for 'sunburn in childhood' (63%), whereas awareness was high for 'use of sunbeds' (91%) and 'mole change' (97%). Lack of awareness of 'sunburn in childhood' was more prevalent among respondents from Norway [PR = 1.38 (1.28-1.48)] but less prevalent among respondents from Northern Ireland (NI) [PR = 0.78 (0.72-0.85)] and Sweden [PR = 0.86 (0.79-0.93)] compared with respondents from Denmark. Lack of awareness of 'use of sunbeds' was more prevalent among respondents from Norway [PR = 2.99 (2.39-3.74)], Sweden [PR = 1.57 (1.22-2.00)], and NI [PR = 1.65 (1.30-2.10)] compared with respondents form Denmark. Being a man, age ≥70, living alone, and having lower education, were each independently associated with lack of MM-awareness. The results indicate relatively low awareness of 'sunburn in childhood' as a risk factor for MM, and important disparities in MM-awareness across countries and socio-demographic groups. Improved and more directed initiatives to enhance public MM-awareness, particularly about 'sunburn in childhood', are needed. © The Author 2015. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

  13. Spring flood pH decline in northern Sweden: Towards an operational model separating natural acidity from anthropogenic acidification

    Energy Technology Data Exchange (ETDEWEB)

    Laudon, H.

    1999-10-01

    The spring flood is a defining feature of the ecosystem in northern Sweden. In this region, spring flood is an occasion for dramatic hydrochemical changes that profoundly effect the biodiversity of the aquatic ecosystem. Spring flood is also the period most susceptible to anthropogenic acidification. A belief in the anthropogenic component to pH decline during spring flood has been an important factor in spending over half a billion crowns to lime surface waters in Northern Sweden during the last decade. The natural component of episodic pH decline during spring flood, however, has received less attention. The main objective of this work is to present an operational model for separating and quantifying the anthropogenic and natural contributions of episodic acidification during high flow events in Northern Sweden. The key assumptions in this model are that baseflow ANC has not been affected by anthropogenic acidification, that DOC has not changed due to modern land-use practice and that natural dilution during hydrological episodes can be quantified. The limited data requirements of 10-15 stream water samples before and during spring flood make the model suitable for widespread use in environmental monitoring programs. This makes it possible to distinguish trends of human impact as well as natural pH decline in space and time. Modeling results from northern Sweden demonstrate that the natural driving mechanisms of dilution and organic acidity were the dominant factors in the episodic acidification of spring flood in the region. The anthropogenic contribution to spring pH decline was similar in size to the natural contribution in only two of the more than 30 events where this model was applied. Natural factors alone were found to cause pH values below 4.5 in some streams. Anthropogenic sources of acidity can be superimposed on this natural dynamics. In the sites studied, the magnitude of the anthropogenic ANC decline was correlated to the winter deposition of

  14. Air pollution in northern Sweden. Deposition, levels and effects Oct 1994 - Sep 1995; Luftfoeroreningar i norra Sverige. Nedfall, halter och effekter oktober 1994 - september 1995

    Energy Technology Data Exchange (ETDEWEB)

    Hallgren-Larsson, E; Sjoeberg, K; Westling, O

    1996-06-01

    The purpose of the monitoring programme is to quantify sulphur and nitrogen deposition to forests, and to illustrate possible acidification of the soil. Deposition is investigated by precipitation studies in open field areas and as throughfall. Soil water chemistry in the forest stands is used as indicator of soil conditions. Air concentrations of sulphur dioxide, nitrogen dioxide, and ammonia were measured at two sites in the county of Jaemtland. This report concerns the hydrological year from October 1994 through September 1995 for 17 locations in the four most northern counties of Sweden. The results are compared with previous years and other regions in Sweden. The results shows a gradient with more precipitation, higher concentrations and larger deposition of sulphur and nitrogen at coastal than at inland locations. Mean from all 17 locations were pH 4.8 and sulphur concentration 0.4 mg/l (SO{sub 4}-S{sub ex}). Concentrations of nitrogen as nitrate and as ammonium were about 0.2 mg/l each. About half of the locations received larger amounts than target loads set for northern Sweden. Deposition of sulphur decreased in the county of Norrbotten during the last 4 years. Greater loads of sulphur and nitrogen were deposited in southern than in northern Sweden. The most acidified soil solutions (pH 4.5-4.6) with highest concentrations of aluminium were found at coastal locations outside Luleaa and Umeaa. At many locations in southern Sweden acidified soil solutions, rich in aluminium and poor in base cations, were detected. Similar conditions were found at two coastal locations in northern Sweden. Highest air concentrations of sulphur dioxide were found during January 1995. Nitrogen dioxide concentrations were highest during November 1994 through March 1995. A gradient of air concentrations of sulphur dioxide was found, with decreasing concentrations from southern to northern Sweden. 15 refs, 57 figs, 11 tabs

  15. Stable carbon and oxygen isotope studies of Late Weichselian lake sediments in southern Sweden and northern Poland, with palaeoclimatic implications

    International Nuclear Information System (INIS)

    Hammarlund, D.

    1994-04-01

    Late Weichselian lacustrine sediment sequences from southern Sweden and northern Poland were studied by means of stable isotope analysis in order to reconstruct the climatic development and climatically induced environmental changes in the respective regions. The methods used include analyses of the stable carbon isotope composition (δ 13 C) of bulk organic material, and the stable carbon and oxygen isotope compositions (δ 13 C, δ 18 O) of bulk carbonates and carbonate shells of aquatic organisms. These results were complemented and supported by lithological, chemical and biostratigraphic data (plant macrofossils, insects, molluscs). Chronological data were obtained by AMS radiocarbon dates and correlations based on pollen analysis. At c. 12.400 BP a climatic change from arctic, dry, and continental, to subarctic and more humid and maritime conditions occurred in southern Sweden. The Older Dryas stadial (c.12.200-12.000 BP) is characterized by a temporary return to generally colder , drier, and more continental conditions, followed by generally favourable (subarctic), although unstable, climatic conditions. At c. 11.300 BP a gradual transition towards a colder and more continental climate was initiated, followed by total absence of limnic carbonates during the Younger Dryas stadial (c. 11.000-10.200 BP), indicating arctic and continental conditions. The transition to the Holocene is characterized by a rapid and strong climatic warming. The results from northern Poland point to some important differences compared to this development. A climatic warming around 13.000 BP was followed by generally favourable climatic conditions enabling continuous sedimentation of limnic carbonates during the Late Weichselian. Distinct depletions of 13 C in lacustrine organic material at the transition to the Holocene were recorded in southern Sweden, also demonstrated by decreasing mean values obtained from an extensive compilation of δ 13 C data. A number of processes that may

  16. Frost heaving of planted tree seedlings in the boreal forest of northern Sweden

    International Nuclear Information System (INIS)

    Goulet, France

    2000-01-01

    Frost heaving can be a leading cause of tree seedling mortality in many places in the boreal forest of Northern Sweden. The aim of this investigation was to improve our understanding of frost heaving of planted tree seedlings as related to snow cover, scarification, planting methods and soil types. The thesis is based on a review paper, three field experiments and one laboratory experiment. The experiments focus on different methods to control frost heaving of forest tree seedlings and on a number of factors affecting the extent of frost heaving. The review paper identifies the many aspects of frost heaving of forest tree seedlings and agricultural crops based on an intensive review of the research contributions made during the last century. Even if many investigations have been carried out with the aim to decrease the extent of frost heaving, very little quantitative results are available for tree seedlings. In a field experiment, the choice of planting positions was effective in decreasing frost heaving of planted seedlings following mounding or disc-trenching. Seedlings planted in the depressions were largely affected by frost heaving with a maximal vertical displacement of 5.4 cm while frost heaving did not occur on the top of the mound. On the other hand, the planting time and planting depth had no influence on the extent of frost heaving. In another field experiment the size of the scarified patches was strongly correlated to frost heaving which reached between 7.6 and 11.5 cm in 4 and 8-dm patches compared to between 4.4 and 5.3 in non-scarified soil and in a 1-dm patch. Ground vegetation probably decreases the diurnal temperature variation and the number of freezing-thawing cycles. The duration and magnitude of frost temperatures, the frost hour sum, increased with patch size. The difference between the 8-dm and 1-dm patch increased to 2064 hour-degrees at the end of the winter. In larger patches, the planting depth seemed to be effective in reducing the

  17. Establishment of Cladonia stellaris after artificial dispersal in an unfenced forest in northern Sweden

    Directory of Open Access Journals (Sweden)

    Samuel Roturier

    2009-12-01

    Full Text Available In 2002, fragments and whole thalli of reindeer lichen, mainly Cladonia stellaris, were spread in a typical Scots pine forest in northern boreal Sweden to study the survival and development after artificial lichen dispersal. The forest was not fenced, allowing reindeer access to graze. Lichens were dispersed in intact vegetation in 1 m2 plots by one of two methods: either as an intact lichen mat (patch of 0.25 m2 in the centre of the plot or as fragments scattered (scatter across the whole plot. The lichen was then monitored by photo inventory. In 2006, three years after the first inventory, all patch plots had been partially grazed by reindeer and the lichen cover measured in both patch and scatter plots had decreased severely. In 2008, the lichen cover in the patch and scatter plots had increased by up to 54% and 88%, respectively, of the cover measured during the first inventory in 2003. A significant increase in the number of fragments in the plots was also observed between 2006 and 2008, suggesting that in addition to growing like naturally established thalli, the lichen had spread and slowly colonized the plots. Dispersing lichen by the “patch” method appears to be less costefficient than the “scatter” method, if the area is grazed by reindeer. These results support the hypothesis that dispersal of reindeer lichen could be an effective means of restoring lichen stands, which are important for reindeer husbandry, even if the area is open to reindeer grazing. Abstract in Swedish / Sammanfattning: Etablering av Cladonia stellaris efter artificiell spridning i ej inhägnad skog i norra Sverige Renlav (främst Cladonia stellaris spreds manuellt 2002 i en talldominerad skog i norra Sverige för att studera lavens etablering efter artificiell spridning. Försöksområdet var inte hägnat utan öppet för renbete. Laven spreds i intakt markvegetation på 1 m2-ytor, antingen i form av intakta lavbålar (0,25 m2 i ytans centrum eller som

  18. Frost heaving of planted tree seedlings in the boreal forest of northern Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Goulet, France

    2000-07-01

    Frost heaving can be a leading cause of tree seedling mortality in many places in the boreal forest of Northern Sweden. The aim of this investigation was to improve our understanding of frost heaving of planted tree seedlings as related to snow cover, scarification, planting methods and soil types. The thesis is based on a review paper, three field experiments and one laboratory experiment. The experiments focus on different methods to control frost heaving of forest tree seedlings and on a number of factors affecting the extent of frost heaving. The review paper identifies the many aspects of frost heaving of forest tree seedlings and agricultural crops based on an intensive review of the research contributions made during the last century. Even if many investigations have been carried out with the aim to decrease the extent of frost heaving, very little quantitative results are available for tree seedlings. In a field experiment, the choice of planting positions was effective in decreasing frost heaving of planted seedlings following mounding or disc-trenching. Seedlings planted in the depressions were largely affected by frost heaving with a maximal vertical displacement of 5.4 cm while frost heaving did not occur on the top of the mound. On the other hand, the planting time and planting depth had no influence on the extent of frost heaving. In another field experiment the size of the scarified patches was strongly correlated to frost heaving which reached between 7.6 and 11.5 cm in 4 and 8-dm patches compared to between 4.4 and 5.3 in non-scarified soil and in a 1-dm patch. Ground vegetation probably decreases the diurnal temperature variation and the number of freezing-thawing cycles. The duration and magnitude of frost temperatures, the frost hour sum, increased with patch size. The difference between the 8-dm and 1-dm patch increased to 2064 hour-degrees at the end of the winter. In larger patches, the planting depth seemed to be effective in reducing the

  19. Pilot project wind power - Large scale wind power in northern Sweden; Pilotprojekt vindkraft - Storskalig vindkraft i norra Sverige

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    The Swedish Energy Agency granted 2009-04-20 Svevind AB financial aid to implement {sup P}ilot project wind power- Large scale wind power in northern Sweden{sup .} The purpose of the aid is to implement pilot sub-projects in wind power, to to increase knowledge for the larger establishments. The Energy Agency said in its decision that the projects Dragaliden and Gabriel Mountain is of 'great importance for future large-scale development of wind power in Sweden'. The special conditions prevailing in the project, forest environment and cold climate, gives the possibility of studies of wind turbines on birds, reindeer herding and hunting and the more technical aspects, such as de-icing and obstacle lighting. The objectives of the project, in addition to the construction and operation of 32 wind turbines, has been to include evaluating the permit process, studying the social effects around the wind power, to study the impact on small game hunting, perform tests of the de-icing system, investigate impacts on reindeer herding and explain the outcome of the project-generated rural funds. Some of the above sub-projects have been completed, which are reported in this report. For the sub-projects still in progress, the report presents the results to date, until the completion.

  20. Association of Seasonal Climate Variability and Age-Specific Mortality in Northern Sweden before the Onset of Industrialization

    Directory of Open Access Journals (Sweden)

    Joacim Rocklöv

    2014-07-01

    Full Text Available Background and aims: Little is known about health impacts of climate in pre-industrial societies. We used historical data to investigate the association of temperature and precipitation with total and age-specific mortality in Skellefteå, northern Sweden, between 1749 and 1859. Methods: We retrieved digitized aggregated population data of the Skellefteå parish, and monthly temperature and precipitation measures. A generalized linear model was established for year to year variability in deaths by annual and seasonal average temperature and cumulative precipitation using a negative binomial function, accounting for long-term trends in population size. The final full model included temperature and precipitation of all four seasons simultaneously. Relative risks (RR with 95% confidence intervals (CI were calculated for total, sex- and age-specific mortality. Results: In the full model, only autumn precipitation proved statistically significant (RR 1.02; CI 1.00–1.03, per 1cm increase of autumn precipitation, while winter temperature (RR 0.98; CI 0.95–1.00, per 1 °C increase in temperature and spring precipitation (RR 0.98; CI 0.97–1.00 per 1 cm increase in precipitation approached significance. Similar effects were observed for men and women. The impact of climate variability on mortality was strongest in children aged 3–9, and partly also in older children. Infants, on the other hand, appeared to be less affected by unfavourable climate conditions. Conclusions: In this pre-industrial rural region in northern Sweden, higher levels of rain during the autumn increased the annual number of deaths. Harvest quality might be one critical factor in the causal pathway, affecting nutritional status and susceptibility to infectious diseases. Autumn rain probably also contributed to the spread of air-borne diseases in crowded living conditions. Children beyond infancy appeared most vulnerable to climate impacts.

  1. Contrasting landscape influences on sediment supply and stream restoration priorities in northern Fennoscandia (Sweden and Finland) and coastal British Columbia.

    Science.gov (United States)

    Rosenfeld, Jordan; Hogan, Daniel; Palm, Daniel; Lundquist, Hans; Nilsson, Christer; Beechie, Timothy J

    2011-01-01

    Sediment size and supply exert a dominant control on channel structure. We review the role of sediment supply in channel structure, and how regional differences in sediment supply and land use affect stream restoration priorities. We show how stream restoration goals are best understood within a common fluvial geomorphology framework defined by sediment supply, storage, and transport. Land-use impacts in geologically young landscapes with high sediment yields (e.g., coastal British Columbia) typically result in loss of in-stream wood and accelerated sediment inputs from bank erosion, logging roads, hillslopes and gullies. In contrast, northern Sweden and Finland are landscapes with naturally low sediment yields caused by low relief, resistant bedrock, and abundant mainstem lakes that act as sediment traps. Land-use impacts involved extensive channel narrowing, removal of obstructions, and bank armouring with boulders to facilitate timber floating, thereby reducing sediment supply from bank erosion while increasing export through higher channel velocities. These contrasting land-use impacts have pushed stream channels in opposite directions (aggradation versus degradation) within a phase-space defined by sediment transport and supply. Restoration in coastal British Columbia has focused on reducing sediment supply (through bank and hillslope stabilization) and restoring wood inputs. In contrast, restoration in northern Fennoscandia (Sweden and Finland) has focused on channel widening and removal of bank-armouring boulders to increase sediment supply and retention. These contrasting restoration priorities illustrate the consequences of divergent regional land-use impacts on sediment supply, and the utility of planning restoration activities within a mechanistic sediment supply-transport framework.

  2. What students do schools allocate to a cognitive-behavioural intervention? Characteristics of adolescent participants in Northern Sweden

    Directory of Open Access Journals (Sweden)

    Heléne Zetterström Dahlqvist

    2015-11-01

    Full Text Available Background: Adolescents are a vulnerable group when it comes to the risk of developing depression. Preventing the onset of depressive episodes in this group is therefore a major public health priority. In the last decades, school-based cognitive-behavioural interventions have been a common primary prevention approach. However, evidence on what girls actually are allocated to such interventions when no researchers are involved is scarce. Objective: To explore how a selective cognitive-behavioural program (Depression In Swedish Adolescents developed to prevent depression in adolescents, was implemented in a naturalistic setting in schools in northern part of Sweden. The focus was on characteristics of participants allocated to the intervention. Design: Cross-sectional baseline data on depressive symptoms, school environment and socio-economic factors were collected in 2011 by means of questionnaires in schools in a municipality in the northern part of Sweden. Intervention participants were identified in a follow-up questionnaire in 2012. Students (n=288 included in the analyses were in the ages of 14–15. Results: Sixty-six girls and no boys were identified as intervention participants. They reported higher levels of depressive symptoms, lower personal relative affluence, more sexual harassment victimization and less peer support compared to female non-participants (n=222. Intervention participants were more likely to attend schools with a higher proportion of low parental education levels and a lower proportion of students graduating with a diploma. Conclusions: The developers of the intervention originally intended the program to be universal or selective, but it was implemented as targeted in these schools. It is important for school administrations to adhere to program fidelity when it comes to what students it is aimed for. Implications for effectivenss trials of cognitive-behavioural interventions in the school setting is discussed.

  3. More distinct food intake patterns among women than men in northern Sweden: a population-based survey

    Directory of Open Access Journals (Sweden)

    Weinehall Lars

    2009-02-01

    Full Text Available Abstract Background The need to promote a healthy diet to curb the current obesity epidemic has today been recognized by most countries. A prerequisite for planning and evaluating interventions on dietary intake is the existence of valid information on long-term average dietary intake in a population. Few large, population-based studies of dietary intake have been carried out in Sweden. The largest to date is the Västerbotten Intervention Program (VIP, which was initiated in 1985, with data collection still ongoing. This paper reports on the first comprehensive analyses of the dietary data and presents dietary intake patterns among over 60,000 women and men in northern Sweden during 1992–2005. Methods Between 1992 and 2005, 71,367 inhabitants in Västerbotten county aged 30, 40, 50, and 60 years visited their local health care center as part of the VIP. Participants of VIP filled in an 84- or 64-item food frequency questionnaire (FFQ and provided sociodemographic information. Complete and realistic information on consumption frequency was provided by 62,531 individuals. Food intake patterns were analyzed using K-means cluster analyses. Results The mean daily energy intake was 6,83 (± 1,77 MJ among women and 8,71 (± 2,26 MJ among men. More than half of both women and men were classified as Low Energy Reporters (defined as individuals reporting a food intake level below the lower 95% confidence interval limit of the physical activity level. Larger variation in frequency of daily intake was seen among women than among men for most food groups. Among women, four dietary clusters were identified, labeled "Fruit and vegetables", "High fat", "Coffee and sandwich", and "Tea and ice cream". Among men, three dietary clusters were identified, labeled "Fruit and vegetables", "High fat", and "Tea, soda and cookies". Conclusion More distinct food intake patterns were seen among women than men in this study in northern Sweden. Due to large proportions of

  4. Time trends in burdens of cadmium, lead, and mercury in the population of northern Sweden

    International Nuclear Information System (INIS)

    Wennberg, Maria; Lundh, Thomas; Bergdahl, Ingvar A.; Hallmans, Goeran; Jansson, Jan-Hakan; Stegmayr, Birgitta; Custodio, Hipolito M.; Skerfving, Staffan

    2006-01-01

    The time trends of exposure to heavy metals are not adequately known. This is a worldwide problem with regard to the basis for preventive actions and evaluation of their effects. This study addresses time trends for the three toxic elements cadmium (Cd), mercury (Hg), and lead (Pb). Concentrations in erythrocytes (Ery) were determined in a subsample of the population-based MONICA surveys from 1990, 1994, and 1999 in a total of 600 men and women aged 25-74 years. The study took place in the two northernmost counties in Sweden. To assess the effect of changes in the environment, adjustments were made for life-style factors that are determinants of exposure. Annual decreases of 5-6% were seen for Ery-Pb levels (adjusted for age and changes in alcohol intake) and Ery-Hg levels (adjusted for age and changes in fish intake). Ery-Cd levels (adjusted for age) showed a similar significant decrease in smoking men. It is concluded that for Pb and maybe also Hg the actions against pollution during recent decades have caused a rapid decrease of exposure; for Hg the decreased use of dental amalgam may also have had an influence. For Cd, the decline in Ery-Cd was seen only in smokers, indicating that Cd exposure from tobacco has decreased, while other environmental sources of Cd have not changed significantly. To further improve the health status in Sweden, it is important to decrease the pollution of Cd, and actions against smoking in the community are important

  5. Determinants of waterpipe use amongst adolescents in Northern Sweden: a survey of use pattern, risk perception, and environmental factors.

    Science.gov (United States)

    Ramji, Rathi; Arnetz, Judy; Nilsson, Maria; Jamil, Hikmet; Norström, Fredrik; Maziak, Wasim; Wiklund, Ywonne; Arnetz, Bengt

    2015-09-15

    Determinants of waterpipe use in adolescents are believed to differ from those for other tobacco products, but there is a lack of studies of possible social, cultural, or psychological aspects of waterpipe use in this population. This study applied a socioecological model to explore waterpipe use, and its relationship to other tobacco use in Swedish adolescents. A total of 106 adolescents who attended an urban high-school in northern Sweden responded to an anonymous questionnaire. Prevalence rates for waterpipe use were examined in relation to socio-demographics, peer pressure, sensation seeking behavior, harm perception, environmental factors, and depression. Thirty-three percent reported ever having smoked waterpipe (ever use), with 30% having done so during the last 30 days (current use). Among waterpipe ever users, 60% had ever smoked cigarettes in comparison to 32% of non-waterpipe smokers (95% confidence interval 1.4-7.9). The odds of having ever smoked waterpipe were three times higher among male high school seniors as well as students with lower grades. Waterpipe ever users had three times higher odds of having higher levels of sensation-seeking (95% confidence interval 1.2-9.5) and scored high on the depression scales (95% confidence interval 1.6-6.8) than non-users. The odds of waterpipe ever use were four times higher for those who perceived waterpipe products to have pleasant smell compared to cigarettes (95% confidence interval 1.7-9.8). Waterpipe ever users were twice as likely to have seen waterpipe use on television compared to non-users (95% confidence interval 1.1-5.7). The odds of having friends who smoked regularly was eight times higher for waterpipe ever users than non-users (95% confidence interval 2.1-31.2). The current study reports a high use of waterpipe in a select group of students in northern Sweden. The study adds the importance of looking at socioecological determinants of use, including peer pressure and exposure to media marketing

  6. Traditional ecological knowledge among Sami reindeer herders in northern Sweden about vascular plants grazed by reindeer

    Directory of Open Access Journals (Sweden)

    Berit Inga

    2013-03-01

    Full Text Available Traditional knowledge about how reindeer utilize forage resources was expected to be crucial to reindeer herders. Seventeen Sami reindeer herders in four reindeer herding communities in Sweden (“samebyar” in Swedish were interviewed about plants species considered to be important reindeer food plants in scientific literature. Among 40 plant species, which the informants were asked to identify and indicate whether and when they were grazed by reindeer, they identified a total of 21 plant taxa and five plant groups. They especially recognised species that were used as human food by the Sami themselves, but certain specific forage plants were also identified. Detailed knowledge of vascular plants at the species level was surprisingly general, which may indicate that knowledge of pasture resources in a detailed species level is not of vital importance. This fact is in sharp contradiction to the detailed knowledge that Sami people express for example about reindeer (as an animal or snow (as physical element. The plausible explanation is that observations of individual plant species are unnecessarily detailed information in large-scale reindeer pastoralism, because the animals graze freely under loose herding and border surveillance.

  7. Bedrock stability in southeastern Sweden. Evidence from fracturing in the ordovician limestones of northern Oeland

    International Nuclear Information System (INIS)

    Milnes, A.G.; Gee, D.G.

    1992-09-01

    The stability of the bedrock in SE Sweden with regard to radioactive waste disposal has recently been the subject of some controversy. In order to better assess the age and significance of fracturing in the Precambrian basement at the site of the Aespoe Hard Rock Laboratory (HRL), near Oskarshamn, a detailed analysis of fracturing in the lower Ordovician limestones exposed along the west coast of the neighbouring island of Oeland has been carried out. The limestones form continuously exposed shore platforms, in segments up to 30 m broad and several kilometres long. These, and numerous quarries, provide ideal objects for quantitative analysis (ground and air photo mapping, scanline logging), and unique opportunities for investigating the amount of movement on the fractures, because of well-developed bedding and abundant rod-shaped fossils on the bedding surfaces. The fracture patterns are dominated by two sets of subvertical fractures, a NW trending closely spaced and strongly orientated set and a NNE-ENE trending widely spaced and variably orientated set. Only about 10% of the fractures in both sets show lateral fossil displacement, with maximum movement of 5 cm, and only 3% of the fractures show vertical displacement of bedding (maximum 8 cm). All in all, the lower Ordovician limestones along the exposed shoreline have suffered remarkably little deformation since deposition, i.e. over the last 500 million years. Appreciable bedrock instability, if it occurred, must have been concentrated offshore, or in the unexposed segments of the coastline, where some weak indications of slight movement (changes of a few metres in stratigraphic level) have been observed. Among other recommendations for further work, geophysical investigations to test these indications are suggested. (54 refs.)

  8. Using Python for Pedigree Analysis

    Science.gov (United States)

    A pedigree is a way of describing a population of people or animals in terms of genetic relationships among individuals. Pedigrees are of interest to many people, including scientists, animal and plant breeders, and genealogists. They are used to assess the diversity of populations, in combination ...

  9. Arrival of rabbit haemorrhagic disease virus 2 to northern Europe: Emergence and outbreaks in wild and domestic rabbits (Oryctolagus cuniculus) in Sweden.

    Science.gov (United States)

    Neimanis, A S; Ahola, H; Zohari, S; Larsson Pettersson, U; Bröjer, C; Capucci, L; Gavier-Widén, D

    2018-02-01

    Incursion of rabbit haemorrhagic disease virus (RHDV) into Sweden was documented in 1990 and it is now considered endemic in wild rabbit (Oryctolagus cuniculus) populations. Rabbit haemorrhagic disease virus 2 (RHDV2), a new, related lagovirus was first detected in France in 2010, and has spread rapidly throughout Europe and beyond. However, knowledge of RHDV2 in northern Europe is sporadic and incomplete, and in Sweden, routinely available diagnostic methods to detect rabbit haemorrhagic disease (RHD) do not distinguish between types of virus causing disease. Using RHDV2-specific RT-qPCR, sequencing of the VP60 gene and immunological virus typing of archived and prospective case material from the National Veterinary Institute's (SVA) wildlife disease surveillance programme and diagnostic pathology service, we describe the emergence of RHDV2 in Sweden in both wild and domestic rabbits. The earliest documented outbreak occurred on 22 May 2013, and from May 2013 to May 2016, 10 separate incidents of RHDV2 were documented from six different municipalities in the southern half of Sweden. Phylogenetic analysis of the VP60 gene shows clear clustering of Swedish isolates into three separate clusters within two different clades according to geographic location and time, suggesting viral evolution, multiple introduction events or both. Almost all cases of RHD examined by SVA from May 2013 to May 2016 were caused by RHDV2, suggesting that RHDV2 may be replacing RHDV as the predominant cause of RHD in Sweden. © 2017 Blackwell Verlag GmbH.

  10. Physiological evaluation of free-ranging moose (Alces alces immobilized with etorphine-xylazine-acepromazine in Northern Sweden

    Directory of Open Access Journals (Sweden)

    Evans Alina L

    2012-12-01

    Full Text Available Abstract Background Evaluation of physiology during capture and anesthesia of free-ranging wildlife is useful for determining the effect that capture methods have on both ecological research results and animal welfare. This study evaluates capture and anesthesia of moose (Alces alces with etorphine-xylazine-acepromazine in Northern Sweden. Methods Fifteen adult moose aged 3–15 years were darted from a helicopter with a combination of 3.37 mg etorphine, 75 mg xylazine, and 15 mg acepromazine. Paired arterial blood samples were collected 15 minutes apart with the first sample at 15–23 minutes after darting and were analyzed immediately with an i-STAT®1 Portable Clinical Analyzer. Results All animals developed hypoxemia (PaO2 2 5.5-8 kPa. All moose were acidemic (ph2, 14 moose had mild hypercapnia (PaCO2 6-8 kPa and two had marked hypercapnia (PaCO2>8 kPa. Pulse, respiratory rate, pH and HCO3 increased significantly over time from darting whereas lactate decreased. Conclusions The hypoxemia found in this study is a strong indication for investigating alternative drug doses or combinations or treatment with supplemental oxygen.

  11. Women's preferences and received pain relief in childbirth - A prospective longitudinal study in a northern region of Sweden.

    Science.gov (United States)

    Lindholm, Annika; Hildingsson, Ingegerd

    2015-06-01

    A range of alternatives in pain management during childbirth are available in the western countries. Women's preferences for and use of pain relief methods during labour is not fully investigated. The aim of this study was to describe what pain relief methods pregnant women preferred when asked in late pregnancy and to identify factors associated with preferred and received pain relief methods. A prospective longitudinal study in a northern region of Sweden (n = 936). Data were collected by three questionnaires. Odds ratios with a 95% confidence interval were calculated between preferred and received pain relief methods for several explanatory variables. The most preferred pain relief methods were also the most common received pain relief methods; nitrous oxide, bathing, breathing techniques, epidural analgesia and massage. The strongest factors for using different pain relief methods were primiparity and preferences. Women who used epidural analgesia, regardless of preference, were two to four times more likely to have a less positive birth experience. Women's preferences for a certain pain relief method were largely met. Greater differences were seen between background factors and preferences than the received pain relief methods. Preferences and primiparity were the most important factors for actually using pain relief. Epidural analgesia was associated with a less positive birth experience. Copyright © 2014 Elsevier B.V. All rights reserved.

  12. Crustal structure in the Kiruna area, northern Sweden, based on seismic reflection profiling

    Science.gov (United States)

    Juhojuntti, Niklas; Bergman, Stefan; Olsson, Sverker

    2013-04-01

    Northernmost Sweden is currently one of the most active mining areas in Europe. In order to better understand the regional three-dimensional crustal structure and to support deep ore exploration, we have acquired a 74 km long seismic reflection profile in the Kiruna area. The upper crust in this area is largely composed of various supracrustal units, which are dominated by metabasalts, acidic metavolcanics and clastic metasedimentary rocks, resting on an Archaean metagranitoid complex. All of these units have been intruded by plutonic rocks, and to variable degrees folded, sheared and metamorphosed, during the Svecokarelian orogeny. The profile crosses several steep ductile shear zones, some of which extend for hundreds of kilometres along strike. Many of the lithological contacts and deformation zones are expected to be seismically reflective. The profile is located only a few kilometres from the world's largest underground iron-ore mine in Kiruna, and closer to the profile there are several known ore bodies, some of which are active exploration targets. For the seismic recording we used approximately 350 geophones in split-spread configuration, at a separation of 25 m. The main seismic source was the Vibsist system (an impact source), which normally was employed at every geophone station. We also fired explosive charges (8-16 kg) at a few locations distributed along the profile to image deeper structures, although at very low resolution. Wireless seismometers were placed along and to the side of the profile, mainly in order to achieve better velocity control and to study out-of-the-plane reflections. Some mining blasts in Kiruna were also recorded. The upper crust in the area is quite reflective, most clearly demonstrated by the dynamite shot records. Some of the reflections appear to originate from steeply dipping structures. The dynamite shot records show a set of reflections at 3-4 s twt, corresponding to a depth of roughly 10 km, the explanation for which is

  13. Factors influencing caesium-137 levels in moose (Alces alces) and small game in Northern Sweden

    International Nuclear Information System (INIS)

    Nelin, P.; Palo, T.R.

    1989-01-01

    In the third annual hunting season after the Chernobyl accident the concentration of Cs-137 in meat of northern Swedish moose was significantly higher than in the first one (1986). In September 1986 the mean Cs concentration was 500 Bq/kg in calves but in September 1988 it has risen 1300 Bq/kg. This increase was only temporary and a rapid decline occured after September and by December 1988 the concentration of Cs was the same as in late 1986. Adult moose showed the same increase during the hunt 1988 but to a lower magnitude. Typical food plants of moose such as bilberry (Vaccinum myrtillus) and birch (Betula pubescens) showed, contradictory to expected by the level in moose, a decline of concentration caesium from 1986 to 1988. A probable explanation to the dramatically increased concentration of Cs in moose is a change in diet selection during 1988. Small mammals such as voles and lemmings showed a variation in concentration of caesium-137 which was more dependent on other factors than on their body size. This emphasize the necessity to study diet selection by herbivores in detail in order to predict uptake and changes in environmental contaminants. (orig.)

  14. A preliminary structural analysis of the pattern of post-glacial faults in Northern Sweden

    International Nuclear Information System (INIS)

    Talbot, C.

    1986-10-01

    The post-glacial kinematics inferred from the structures suggest horizontal NW or WNW compression with lateral relief to the NE at depth below surficial upward relief. These kinematics are sufficiently similar to the kinematics throughout Europe north of the Alps to suspect the neotectonic motion of the Eurasian lithospheric plate over the last 38 or even 58 (+/- 2)Ma as the causative force. Large displacements appear to have occurred within a hundred years or so of the last ice retreating from any particular part of northern Scandinavia. This suggests a sudden relief during glacial unloading (and melting of ground water) of plate tectonic forces accumulated during glacial loading. Recent earthquakes in the region display similar kinematics to the post-glacial fractures on a regional scale but indications of ground movement along the forested fault scarps in the lifetime of the trees is observed at only a few localities. Only geodetic strain measurements or small-earthquake monitoring will resolve whether current ductile or seismic motion is occuring along the most obvious post-glacial scarps. Such investigations are under way. (orig./DG)

  15. A 10-year incidence of acute whiplash injuries after road traffic crashes in a defined population in northern Sweden.

    Science.gov (United States)

    Styrke, Johan; Stålnacke, Britt-Marie; Bylund, Per-Olof; Sojka, Peter; Björnstig, Ulf

    2012-10-01

    To examine the annual incidence of acute whiplash injuries after road traffic crashes in a geographic catchment area in Northern Sweden during the period 2000-2009. Descriptive epidemiology determined by prospectively collected data from a defined population. The study was conducted at a public hospital in Sweden. The population of the hospital's catchment area (136,600 inhabitants in 1999 and 144,500 in 2009). At the emergency department, all injured persons (approximately 11,000 per year) were asked to answer a questionnaire about the injury incident. Data from the medical records also were analyzed. From 2000-2009, 15,506 persons were injured in vehicle crashes. Persons who were subject to an acute neck injury within whiplash-associated disorder grades 1-3 were included. The overall and annual incidences were calculated as incidence. Age, gender, type of injury event, and direction of impact were described. The incidences were compared with national statistics on insurance claims from 2003, 2007, and 2008 to detect changes in the proportions of claims. The annual incidence of acute whiplash injuries. Secondary outcome measures were types of injury events, age and gender distribution, changes in the proportion of rear-end crashes during 2000-2009, and changes in the proportion of insurance claims during 2003-2008. During 2000-2009, 3297 cases of acute whiplash injury were encountered. The overall incidence was 235/100,000/year. The average yearly increase in incidence was 1.0%. Women comprised 51.9% and men 48.1% of the injured. Car occupants (86.4%) and bicycle riders (6.1%) were most frequently injured. The proportion of rear-end crashes decreased from 55% to 45% from 2000-2009. The proportion of insurance claims significantly decreased between 2003 and 2008 (P whiplash injuries after road traffic crashes have been relatively stable during the past decade in our area, except in 2007 and 2008, when a peak occurred. Copyright © 2012 American Academy of Physical

  16. Interdisciplinary study of post-glacial faulting in the Lansjaerv area, Northern Sweden 1986-1988

    International Nuclear Information System (INIS)

    Baeckblom, G.; Stanfors, R.

    1989-12-01

    Post-glacial faults have been recognized in the northern Baltic shield for several decades. It is important to evaluate whether such neotectonic movements can lead to new fracturing or decisively alter the geohydrological or geohydrochemical situation around a final repository for spent nuclear fuel. The post-glacial Lansjaerv fault was chosen for interdisciplinary study because of its relative accessibility. The goals of the study were to assess the mechanisms that caused present day scarps, to clarify the extent of any recent fracturing and to clarify the extent of any ongoing movements. All these objectives were reasonable met through a series of studies. This report describes achievements that have been gained since the study was initiated by SKB 1986. Analysis of geology and geophysics over a 150x200 km region supplemented with seismic networks and field studies at outcrops and trenches set a framework for a cored borehole down to depth of 500 m at the fault. The core has been studied in detail with respect to fracture-infillings in order to analyse mineralogical and geochemical alteration. The borehole has been logged for geophysics, stress, hydraulic conductivity, groundwater pressure and the chemical constituents of the groundwater. Numerical modelling has been undertaken in order to understand the effects of glaciation on the behaviour of a blocky rock mass. Several general conclusions have been made by the interdisciplinary research group. One of the major conclusions is that pre-existing old structures were reactivated by tectonic movements, possibly triggered by deglaciation. In spite of a major earthquake that may have occurred during the deglaciation, and in spite of the anomalous tectonic setting compared to study-sites within SKB:s site investigation programme, the hydraulic conductivity and groundwater chemistry are comparable with results from those sites. (83 figs., 15 tabs., 150 refs.)

  17. Time trends in absolute and relative socioeconomic inequalities in leisure time physical inactivity in northern Sweden.

    Science.gov (United States)

    Szilcz, Máté; Mosquera, Paola A; Sebastián, Miguel San; Gustafsson, Per E

    2018-02-01

    The aim was to investigate the time trends in educational, occupational, and income-related inequalities in leisure time physical inactivity in 2006, 2010, and 2014 in northern Swedish women and men. This study was based on data obtained from the repeated cross-sectional Health on Equal Terms survey of 2006, 2010, and 2014. The analytical sample consisted of 20,667 (2006), 31,787 (2010), and 21,613 (2014) individuals, aged 16-84. Logistic regressions were used to model the probability of physical inactivity given a set of explanatory variables. Slope index of inequality (SII) and relative index of inequality (RII) were used as summary measures of the social gradient in physical inactivity. The linear trend in inequalities and difference between gender and years were estimated by interaction analyses. The year 2010 displayed the highest physical inactivity inequalities for all socioeconomic position indicators, but educational and occupational inequalities decreased in 2014. However, significant positive linear trends were found in absolute and relative income inequalities. Moreover, women had significantly higher RII of education in physical inactivity in 2014 and significantly higher SII and RII of income in physical inactivity in 2010, than did men in the same years. The recent reduction in educational and occupational inequalities following the high inequalities around the time of the great recession in 2010 suggests that the current policies might be fairly effective. However, to eventually alleviate inequities in physical inactivity, the focus of the researchers and policymakers should be directed toward the widening trends of income inequalities in physical inactivity.

  18. Explaining linkages (and lack of) between riparian vegetation biodiversity and geomorphic complexity in restored streams of northern Sweden

    Science.gov (United States)

    Polvi, Lina; Maher Hasselquist, Eliza; Nilsson, Christer

    2014-05-01

    Ecological theory suggests that species richness and habitat heterogeneity are positively correlated; therefore stream restoration often relies on increasing geomorphic complexity to promote biodiversity. However, past studies have failed to demonstrate a link between post-restoration biodiversity and geomorphic complexity. These studies have usually relied on only one metric for quantifying complexity, rather than a holistic metric for complexity that represents several aspects of the channel morphology, and have based their observations in catchments with widespread land-use impacts. We use a geomorphic complexity gradient based on five geomorphic aspects (longitudinal, cross-sectional, planform, sediment texture, and instream wood) to determine whether streams with higher levels of complexity also have greater riparian vegetation biodiversity. We also compare biodiversity values with the potential complexity of reaches based on the large-scale controls of valley and channel gradient and the presence of large glacial legacy sediment (boulders). We focus on tributary channels in boreal forests of northern Sweden, where stream modification associated with log-floating from the 1850s to the 1960s created highly simplified channels. Driven by concerns for fish, restoration began in the 1970s by returning large cobbles and boulders into the main channel from the channel edge, and evolved into 'demonstration restoration,' placing very large boulders and trees into the channel, reopening side channels, and constructing fish spawning areas. We evaluate 22 reaches along tributaries of the Vindel River in northern Sweden with four restoration statuses: channelized, restored, demonstration restored, and unimpacted. Detailed morphologic, sediment, and instream wood data allow calculation of 29 metrics of geomorphic complexity, from which a complexity gradient was identified using multivariate statistics. The percent cover of riparian vegetation was identified in 0.5 x 0.5 m

  19. Transfer of radiocaesium from soil to vegetation and to grazing lambs in a mountain area in northern Sweden

    International Nuclear Information System (INIS)

    Rosen, K.; Loensjoe, H.; Andersson, I.

    1994-01-01

    In the northern Arctic and boreal regions many radioecological problems appear in the terrestrial environment. The climate and the soil, and as a consequence also the vegetation types, favour a high transfer of radionuclides to the food chain. Consequently there is a risk for high transfer to domestic animals grazing in these environments. As most of the lamb production in the Nordic countries is carried out on permanent pasture and in semi-natural environments the radioecological and economic effects are evident. This investigation was initiated and supported by the Nordic Nuclear Safety Research Programme (NKS), working group RAD-3, as a part of an inter Nordic research programme. All the Nordic countries, i.e. Denmark, the Faroe Islands, Finland, Iceland, Norway and Sweden, have participated in the project. The sampling technique for soil, herbage and lamb was to be the same in all countries, in areas where no countermeasures had been applied after the Chernobyl fallout. The main results of these common Nordic studies will be summarized by Hove et al., 1994. The Swedish part of the study has also been financially supported by the Swedish Radiation Protection Institute in Stockholm. The purpose was to study the transfer of radiocaesium from soil to plants and further to lamb meat in natural or semi-natural areas over the years. This paper is an extended summary of a work (Rosen et al., 1994) to be published in Journal of Environmental Radioactivity. In the present report only results of soil and transfer from soil to vegetation and lambs are given. (author)

  20. Transfer of radiocaesium from soil to vegetation and to grazing lambs in a mountain area in northern Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Rosen, K; Loensjoe, H [Department of Radioecology, Swedish University of Agricultural Sciences, 75007 Uppsala (Sweden); Andersson, I [Department of Biosystems and Technology, Swedish University of Agricultural Sciences, Alnarp, 23053 (Sweden)

    1994-11-01

    In the northern Arctic and boreal regions many radioecological problems appear in the terrestrial environment. The climate and the soil, and as a consequence also the vegetation types, favour a high transfer of radionuclides to the food chain. Consequently there is a risk for high transfer to domestic animals grazing in these environments. As most of the lamb production in the Nordic countries is carried out on permanent pasture and in semi-natural environments the radioecological and economic effects are evident. This investigation was initiated and supported by the Nordic Nuclear Safety Research Programme (NKS), working group RAD-3, as a part of an inter Nordic research programme. All the Nordic countries, i.e. Denmark, the Faroe Islands, Finland, Iceland, Norway and Sweden, have participated in the project. The sampling technique for soil, herbage and lamb was to be the same in all countries, in areas where no countermeasures had been applied after the Chernobyl fallout. The main results of these common Nordic studies will be summarized by Hove et al., 1994. The Swedish part of the study has also been financially supported by the Swedish Radiation Protection Institute in Stockholm. The purpose was to study the transfer of radiocaesium from soil to plants and further to lamb meat in natural or semi-natural areas over the years. This paper is an extended summary of a work (Rosen et al., 1994) to be published in Journal of Environmental Radioactivity. In the present report only results of soil and transfer from soil to vegetation and lambs are given. (author)

  1. The Impact of Local Participation on Community Support for Natural Resource Management: The Case of Mining in Northern Canada and Northern Sweden

    Directory of Open Access Journals (Sweden)

    Sverker C. Jagers

    2018-06-01

    Full Text Available Due to its oftentimes complex, contested, and multi-scale character, natural resource management (NRM tends to be a challenging task that has been met with various political approaches in order to meet demands for legitimacy. One approach to enhancing the legitimacy of NRM that has gained increased attention within the academic literature is the adoption of local participatory democracy in decision-making processes. Advocates of participatory democracy in NRM propose that local participation achieves the following outcomes: increased legitimacy because it ensures that local needs and priorities are successfully met; decision-making based on more complete information, which helps avoid unexpected negative outcomes; and a sense of belonging and influence among the public, leading to increased perceptions of support and partnership, as opposed to NRM which is imposed on the community. Nevertheless, comprehensive empirical studies that document how public participation affects legitimacy remain rare. Using 2015 data collected on people’s attitudes towards mining in northern Saskatchewan, Canada, and Norrbotten and Västerbotten counties, Sweden, this paper empirically assesses whether and how perceptions of local participation affect the legitimacy of mining development. In turn, this paper finds that perceived public participation does affect the public’s propensity to support mining development and this propensity is mediated by people’s perceptions of the interests present in the decision-making process, their normative beliefs concerning which actors should be allowed to participate in the decision-making process, and certain individual-level and contextual-level factors.

  2. Zn-Pb Ores of Mississippi Valley Type in the Lycksele-Storuman District, Northern Sweden: A Possible Rift-Related Cambrian Mineralisation Event

    Directory of Open Access Journals (Sweden)

    Kjell Billström

    2012-06-01

    Full Text Available The epigenetic Zn-Pb deposits in the Lycksele-Storuman ore district, northern Sweden, are hosted by Paleoproterozoic basement near the margin of the Caledonian mountains. A paleogeographic reconstruction suggests that platform sediments, including Cambrian shales, overlaid the mineralised basement. The mineralisation type, containing sphalerite, galena, calcite and fluorite, is confined to veins and breccias and interpreted to be of Mississippi Valley Type (MVT style. There is no appreciable wall rock alteration. Fluid inclusion work reveals coexisting aqueous and hydrocarbon fluids. Ore deposition is interpreted to have occurred during mixing of two fluids; a cool (

  3. Neotectonics in northern Sweden

    International Nuclear Information System (INIS)

    Henkel, H.; Hult, K.; Eriksson, L.

    1983-05-01

    The report treats the geophysical aspects of the late quartenary faults and the connection between these faults and older fracture zones. Around the Lansjaerv fault, older regional and local faults systems have been mapped out by aeromagnetic interpretation. The interpretation in the vicinity of the fault was made from high resolution aeromagnetic data, augmented with ground geophysical surveys. It has been found that the late quartenary faults at Lansjaerv are largely influenced by the older quartenary faults but that fracturing outside of these zones are quite common. Possible mechanisms, i.e. post-glacial uplift and plate tectonic motion, of the late quartenaily fault are preliminary discussed. Also around the Kaerkejaure fault, aeromagnetic interpretation from high resolution data has been made. This has revealed that the fault entirely follows the older fault zone, that previously has escaped detection. It has also been found that the late quartenary fault has been influenced by the local fracture system belonging to the Kaerkejaure gabbro. At the Lansjaerv fault, seismic refraction investigations has been made. The results indicate that late quartenary block motion has occured at several events. Airborne electromagnetic (RAMA) surveys over late quartenary faults are discussed and compared with ground electromagnetic methods. It is shown that the late quartenary faults genarally are represented by conductive zones in the bedrock, i.e. water-bearing fracture zones. Ground and geophysical data from earlier ore prospecting have been used, toghether with supplementary surveys, for the investigation of the faults of the Paervie complex. It has been found that at Tjaarrojaakka, the Paervie fault coincides with an older tectonic zone. The seismic survey undertaken indicates that substantial preglacial displacement has occured at the zone. (BoK)

  4. Risks associated with the introduction of Pinus contorta in northern Sweden with special attention to Gremmeniella abietina and North American rusts

    International Nuclear Information System (INIS)

    Witzell, J.

    1999-01-01

    Sixty years after the first plantings of the North American Pinus contorta in northern Sweden and twenty years after start of the large scale planting programme, extensive epidemics of the native pathogen Gremmeniella abietina were recorded. A period with extremely cool and rainy summers (1984-1987) followed by a mild winter with large amounts of snow, appeared to be an important predisposing factor to the epidemics. There was a strong negative correlation between disease incidence of G. abietina and temperature sum at the site. The most severe attacks by G. abietina occurred in topographic depressions, on flat ground, and on sites where Picea abies was the dominant species of the old stand. The frequency of trees with stem cankers caused by G. abietina increased during the period of the study. Some cankers had fully girdled the stem and some were completely occluded at the end of the study period. A large proportion of wood damaged by G. abietina adversely influenced processability, and reduced the quality of kraft pulp, and should be sorted out and classed as not perfect raw material. G. abietina was found less frequently in regenerations of native Pinus sylvestris than in those of P. contorta. P. sylvestris showed susceptibility to the North American rusts Endocronartium harknessii, Cronartium coleosporioides and Cronartium comandrae. It was especially susceptible to Endocronartium harknessii, even though disease incidence was low in the studied areas. A high susceptibility to Endocronartium harknessii was found in the P. contorta provenances originating from the Yukon, and most frequently used in Sweden. The risk of a recurrence of predisposing weather conditions with subsequent epidemics of G. abietina in healthy P. contorta plantations should be considered, as well as the risk of severe epidemics on less affected plantations of P. sylvestris due to the high inoculum in nearby P. contorta plantations. Also the risk of North American rusts causing severe

  5. Survival of brown trout during spring flood in DOC-rich streams in northern Sweden: the effect of present acid deposition and modelled pre-industrial water quality

    International Nuclear Information System (INIS)

    Laudon, Hjalmar; Poleo, Antonio B.S.; Voellestad, Leif Asbjoern; Bishop, Kevin

    2005-01-01

    Mortality and physiological responses in brown trout (Salmo trutta) were studied during spring snow melt in six streams in northern Sweden that differed in concentrations of dissolved organic carbon (DOC) and pH declines. Data from these streams were used to create an empirical model for predicting fish responses (mortality and physiological disturbances) in DOC-rich streams using readily accessible water chemistry parameters. The results suggest that fish in these systems can tolerate higher acidity and inorganic aluminium levels than fish in low DOC streams. But even with the relatively low contemporary deposition load, anthropogenic deposition can cause fish mortality in the most acid-sensitive surface waters in northern Sweden during spring flood. However, the results suggests that it is only in streams with high levels of organically complexed aluminium in combination with a natural pH decline to below 5.0 during the spring where current sulphur deposition can cause irreversible damage to brown trout in the region. This study support earlier studies suggesting that DOC has an ameliorating effect on physiological disturbances in humic waters but the study also shows that surviving fish recover physiologically when the water quality returns to less toxic conditions following a toxic high flow period. The physiological response under natural, pre-industrial conditions was also estimated. - High levels of complexed aluminum, at pH levels below 5.0, predisposes brown trout to sulfur-caused damage in the spring

  6. Survival of brown trout during spring flood in DOC-rich streams in northern Sweden: the effect of present acid deposition and modelled pre-industrial water quality

    Energy Technology Data Exchange (ETDEWEB)

    Laudon, Hjalmar [Department of Forest Ecology, Swedish University of Agricultural Sciences, SE-901 83 Umeaa (Sweden)]. E-mail: hjalmar.laudon@sek.slu.se; Poleo, Antonio B.S. [Department of Biology, University of Oslo, P.O. Box 1066 Blindern, N-0316 Oslo (Norway); Voellestad, Leif Asbjoern [Department of Biology, University of Oslo, P.O. Box 1066 Blindern, N-0316 Oslo (Norway); Bishop, Kevin [Department of Environmental Assessment, Swedish University of Agricultural Sciences, SE-750 07 Uppsala (Sweden)

    2005-05-01

    Mortality and physiological responses in brown trout (Salmo trutta) were studied during spring snow melt in six streams in northern Sweden that differed in concentrations of dissolved organic carbon (DOC) and pH declines. Data from these streams were used to create an empirical model for predicting fish responses (mortality and physiological disturbances) in DOC-rich streams using readily accessible water chemistry parameters. The results suggest that fish in these systems can tolerate higher acidity and inorganic aluminium levels than fish in low DOC streams. But even with the relatively low contemporary deposition load, anthropogenic deposition can cause fish mortality in the most acid-sensitive surface waters in northern Sweden during spring flood. However, the results suggests that it is only in streams with high levels of organically complexed aluminium in combination with a natural pH decline to below 5.0 during the spring where current sulphur deposition can cause irreversible damage to brown trout in the region. This study support earlier studies suggesting that DOC has an ameliorating effect on physiological disturbances in humic waters but the study also shows that surviving fish recover physiologically when the water quality returns to less toxic conditions following a toxic high flow period. The physiological response under natural, pre-industrial conditions was also estimated. - High levels of complexed aluminum, at pH levels below 5.0, predisposes brown trout to sulfur-caused damage in the spring.

  7. Subjective health complaints in older adolescents are related to perceived stress, anxiety and gender - a cross-sectional school study in Northern Sweden.

    Science.gov (United States)

    Wiklund, Maria; Malmgren-Olsson, Eva-Britt; Ohman, Ann; Bergström, Erik; Fjellman-Wiklund, Anncristine

    2012-11-16

    Negative trends in adolescent mental and subjective health are a challenge to public health work in Sweden and worldwide. Self-reported mental and subjective health complaints such as pain, sleeping problems, anxiety, and various stress-related problems seem to have increased over time among older adolescents, especially girls. The aim of this study has therefore been to investigate perceived stress, mental and subjective health complaints among older adolescents in Northern Sweden. Data were derived from a cross-sectional school-based survey with a sample consisting of 16-18 year olds (n = 1027), boys and girls, in the first two years of upper secondary school, from different vocational and academic programmes in three public upper secondary schools in a university town in northern Sweden. Prevalence of perceived stress, subjective health complaints, general self-rated health, anxiety, and depression were measured using a questionnaire, including the Hospital Anxiety and Depression Scale (HADS). A large proportion of both girls and boys reported health complaints and perceived stress. There was a clear gender difference: two to three times as many girls as boys reported subjective health complaints, such as headache, tiredness and sleeping difficulties and musculoskeletal pain, as well as sadness and anxiety. High pressure and demands from school were experienced by 63.6% of girls and 38.5% of boys. Perceived stress in the form of pressure and demands correlated strongly with reported health complaints (r = 0.71) and anxiety (r = 0.71). The results indicate that mental and subjective health complaints are prevalent during adolescence, especially in girls, and furthermore, that perceived stress and demands may be important explanatory factors. Future studies should pay attention to the balance between gender-related demands, perceived control and social support, particularly in the school environment, in order to prevent negative strain and stress

  8. Associations among 25-year trends in diet, cholesterol and BMI from 140,000 observations in men and women in Northern Sweden

    Directory of Open Access Journals (Sweden)

    Johansson Ingegerd

    2012-06-01

    Full Text Available Abstract Background In the 1970s, men in northern Sweden had among the highest prevalences of cardiovascular diseases (CVD worldwide. An intervention program combining population- and individual-oriented activities was initiated in 1985. Concurrently, collection of information on medical risk factors, lifestyle and anthropometry started. Today, these data make up one of the largest databases in the world on diet intake in a population-based sample, both in terms of sample size and follow-up period. The study examines trends in food and nutrient intake, serum cholesterol and body mass index (BMI from 1986 to 2010 in northern Sweden. Methods Cross-sectional information on self-reported food and nutrient intake and measured body weight, height, and serum cholesterol were compiled for over 140,000 observations. Trends and trend breaks over the 25-year period were evaluated for energy-providing nutrients, foods contributing to fat intake, serum cholesterol and BMI. Results Reported intake of fat exhibited two significant trend breaks in both sexes: a decrease between 1986 and 1992 and an increase from 2002 (women or 2004 (men. A reverse trend was noted for carbohydrates, whereas protein intake remained unchanged during the 25-year period. Significant trend breaks in intake of foods contributing to total fat intake were seen. Reported intake of wine increased sharply for both sexes (more so for women and export beer increased for men. BMI increased continuously for both sexes, whereas serum cholesterol levels decreased during 1986 - 2004, remained unchanged until 2007 and then began to rise. The increase in serum cholesterol coincided with the increase in fat intake, especially with intake of saturated fat and fats for spreading on bread and cooking. Conclusions Men and women in northern Sweden decreased their reported fat intake in the first 7 years (1986–1992 of an intervention program. After 2004 fat intake increased sharply for both genders

  9. Reindeer (Rangifer tarandus tarandus feeding on lichens and mushrooms: traditional ecological knowledge among reindeer-herding Sami in northern Sweden

    Directory of Open Access Journals (Sweden)

    Berit Inga

    2009-01-01

    Full Text Available The study was performed in four reindeer-herding districts (Sami villages in northern Sweden. Reindeer herding Sami, born in 1950 or earlier, were interviewed about reindeer foraging behaviour on lichens and mushrooms, especially relating to non-summer grazing habits, and about characteristics of a good winter feeding ground. The informants claimed that lichens are preferably grazed in the wintertime, but that they also may be eaten in the summertime when the weather is cold and humid. Mushrooms were chosen in the autumn months August and September, but according to some informants mushrooms may also be eaten during late autumn (from Oct. when frozen and under the snow. The reindeer herders had different names for lichens, which in general terms describe their appearance and habitat. For mushrooms they only used one Sami name. Ground lichens preferred by reindeer are Cladonia species, while the nitrogen-fixing lichen species such as Nephroma arcticum and Stereocaulon pascale were said not to be preferred by the reindeer. Snow conditions are very important, and the less snow (and the softer it is, the better. Habitats where reindeer herders know from experience that snow conditions tend to be problematic, e.g. in moist and open areas with small trees, are used early in the winter (Oct.–Jan., before too much snow has accumulated. A good winter grazing area should have lichens. It is preferably a dry pine (Pinus sylvestris forest heath with large, old and wide-crowned trees to shelter the ground from snow and thereby ease the cratering by reindeer. Abstract in Swedish / Sammanfattning: Renens (Rangifer tarandus tarandus bete av lavar och svampar: Traditionell ekologisk kunskap bland renskötande samer i norra Sverige Studien genomfördes i fyra renskötseldistrikt (samebyar i norra Sverige. Totalt 22 renskötande samer, födda 1950 eller tidigare, blev intervjuade om renens betande av lavar och svampar, renens vinterbete och om vad som karakt

  10. Subjective health complaints in older adolescents are related to perceived stress, anxiety and gender – a cross-sectional school study in Northern Sweden

    Directory of Open Access Journals (Sweden)

    Wiklund Maria

    2012-11-01

    Full Text Available Abstract Background Negative trends in adolescent mental and subjective health are a challenge to public health work in Sweden and worldwide. Self-reported mental and subjective health complaints such as pain, sleeping problems, anxiety, and various stress-related problems seem to have increased over time among older adolescents, especially girls. The aim of this study has therefore been to investigate perceived stress, mental and subjective health complaints among older adolescents in Northern Sweden. Methods Data were derived from a cross-sectional school-based survey with a sample consisting of 16–18 year olds (n = 1027, boys and girls, in the first two years of upper secondary school, from different vocational and academic programmes in three public upper secondary schools in a university town in northern Sweden. Prevalence of perceived stress, subjective health complaints, general self-rated health, anxiety, and depression were measured using a questionnaire, including the Hospital Anxiety and Depression Scale (HADS. Results A large proportion of both girls and boys reported health complaints and perceived stress. There was a clear gender difference: two to three times as many girls as boys reported subjective health complaints, such as headache, tiredness and sleeping difficulties and musculoskeletal pain, as well as sadness and anxiety. High pressure and demands from school were experienced by 63.6% of girls and 38.5% of boys. Perceived stress in the form of pressure and demands correlated strongly with reported health complaints (r = 0.71 and anxiety (r = 0.71. Conclusions The results indicate that mental and subjective health complaints are prevalent during adolescence, especially in girls, and furthermore, that perceived stress and demands may be important explanatory factors. Future studies should pay attention to the balance between gender-related demands, perceived control and social support, particularly in the

  11. Challenges and strategies for sustaining youth-friendly health services - a qualitative study from the perspective of professionals at youth clinics in northern Sweden.

    Science.gov (United States)

    Thomée, Suzanne; Malm, Desiré; Christianson, Monica; Hurtig, Anna-Karin; Wiklund, Maria; Waenerlund, Anna-Karin; Goicolea, Isabel

    2016-12-21

    Youth-friendly health-care services - those that are accessible, acceptable, equitable, appropriate and effective for different youth subpopulations - are beneficial for youth health, but not easy to implement and sustain. Sweden is among the few countries where youth-friendly health-care services have been integrated within the public health system and sustained for a long time. This study explores the challenges and strategies in providing sustainable youth-friendly health-care services, from the perspective of professionals working in youth clinics in northern Sweden. Eleven semi-structured interviews with various health-care professionals working in youth clinics in northern Sweden were conducted. The interviews were transcribed verbatim, and analysed using thematic analysis in relation to the World Health Organization domains of youth friendliness. Four themes emerged from the analysis of the data: 1) 'Meeting youths on their own terms - the key to ensuring a holistic and youth-centred care' was related to the acceptability and appropriateness of the services; 2) 'Organizational challenges and strategies in keeping professionals' expertise on youth updated' referred to the domain of effectiveness; 3) 'Youth clinics are accessible for those who know and can reach them' was related to the domains of accessibility and equity, and 4) 'The challenge of combining strong directions and flexibility in diverse local realities' focused on the struggle to sustain the youth clinics organization and their goals within the broader health system. Professionals working in youth clinics are perceived as motivated, interested and knowledgeable about youth, and the clinics ensure confidentiality and a youth-centred and holistic approach. Challenges remain, especially in terms of ensuring equitable access to different youth subpopulations, improving monitoring routines and ensuring training and competence for all professionals, independently of the location and characteristics of

  12. Sweden - Physics in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1995-11-15

    In its continual monitoring of physics in its Member States, the European Committee for Future Accelerators (ECFA) recently visited Sweden, where it met at the University of Lund in September. Physics in Sweden is flourishing, with both a long CERN tradition and excellent prospects for future collaboration. On the experimental side, about 80 researchers, including about 30 graduate students, out of a total of 110 (including 50 graduate students), concentrate on CERN for their work. The main centres of experimental activity are: Chalmers- Goteborg; Lund (particle physics and relativistic heavy ion groups), the Royal Institute of Technology - KTH - Stockholm, the University of Stockholm, and Uppsala. Engineering support staff in particle and highenergy nuclear physics number about 25. There is a strong Swedish participation (34 researchers from Lund, Stockholm, and Uppsala) in the Delphi experiment at LEP with a full commitment to higher energy running at LEP2, in the CP-LEAR experiment, JETSET studies at the LEAR low energy antiproton ring and in a LEAR hyperon experiment. Sweden is also well represented in CERN's extensive programme of nuclear and heavy ion physics, with 12 researchers active in the heavy ion programme, and a contingent in the SMC muon beam experiment. The strong Swedish interest in CERN's heavy ion programme was underlined by a special national contribution of 1.5M Swiss francs to the new lead ion injector. At lower energies, there is also good Swedish participation (mainly from the Chalmers Institute) in the Isolde online isotope separator. The national physics community has always appreciated CERN's diversified programmes and has greatly benefited as a result. For the future, there is an important involvement (some 40 physicists) in the ATLAS experiment at CERN's LHC collider. Swedish groups have been active in 11 research and development project for LHC physics. Sweden's heavy ion activity will continue at the RHIC heavy ion collider being

  13. Sweden - Physics in Sweden

    International Nuclear Information System (INIS)

    Anon.

    1995-01-01

    In its continual monitoring of physics in its Member States, the European Committee for Future Accelerators (ECFA) recently visited Sweden, where it met at the University of Lund in September. Physics in Sweden is flourishing, with both a long CERN tradition and excellent prospects for future collaboration. On the experimental side, about 80 researchers, including about 30 graduate students, out of a total of 110 (including 50 graduate students), concentrate on CERN for their work. The main centres of experimental activity are: Chalmers- Goteborg; Lund (particle physics and relativistic heavy ion groups), the Royal Institute of Technology - KTH - Stockholm, the University of Stockholm, and Uppsala. Engineering support staff in particle and highenergy nuclear physics number about 25. There is a strong Swedish participation (34 researchers from Lund, Stockholm, and Uppsala) in the Delphi experiment at LEP with a full commitment to higher energy running at LEP2, in the CP-LEAR experiment, JETSET studies at the LEAR low energy antiproton ring and in a LEAR hyperon experiment. Sweden is also well represented in CERN's extensive programme of nuclear and heavy ion physics, with 12 researchers active in the heavy ion programme, and a contingent in the SMC muon beam experiment. The strong Swedish interest in CERN's heavy ion programme was underlined by a special national contribution of 1.5M Swiss francs to the new lead ion injector. At lower energies, there is also good Swedish participation (mainly from the Chalmers Institute) in the Isolde online isotope separator. The national physics community has always appreciated CERN's diversified programmes and has greatly benefited as a result. For the future, there is an important involvement (some 40 physicists) in the ATLAS experiment at CERN's LHC collider. Swedish groups have been active in 11 research and development project for LHC physics. Sweden's heavy ion activity will continue at the RHIC

  14. Demonstration cultivation of Salix in northern Sweden with a focus on frost resistance; Demonstrationsodling av Salix i Norrland med frosttolerans i fokus

    Energy Technology Data Exchange (ETDEWEB)

    Soederstroem, Yvonne

    2010-06-15

    This project is part of the Thermal Engineering Research Association's (Vaermeforsk) programme 'Crops from field to energy production' and the goal is to convince growers to begin cultivating Salix in the northern part of Sweden. The project will demonstrate whether it is possible to grow Salix and examine what type of Salix (the report refers to the different types as Tora, Karin and Gudrun) is most frost-resistant and resistant to insects, fungal infections and animals. The project is aimed primarily at landowners and energy companies. The results showed that growth at the demonstration plots was moderate and the establishment rate was considered good. Growth has been uneven across the fields. At Eriksgaard, about 75% of the plants survived the winter. Survival was determined by the number of plants missing and dead. Additional plants were planted at the sites in 2009. No major insect or leaf fungus attacks were noted at either Eriksgaard or Soergaard, but they both experienced grazing from deer and elk. The rating showed that the herbicide treatment was not sufficient on the demonstration fields. For this reason, a comparison of average lengths was performed of Gudrun in Bodum, where the weeds had not grown as much. The comparison showed that the difference in growth was not significant in the autumn 2008, but the plants in Bodum had grown more by autumn 2009. Topping was not performed in the spring 2009 so that the plants would have an opportunity to grow higher than the weeds and the plants would have an opportunity to have a growth spurt. A comparison of Tora, Karin and Gudrun in Roedoen showed moderate growth for the three types. There were variations in the rows and across the field, mostly for Tora and Karin. Gudrun had lower, but more consistent growth across the field. During the summer 2009, survival was rated for the plants in Roedoen. This rating showed that 90% of Tora, 60% of Karin and 70% of Gudrun had survived the winter. The Salix

  15. ON PEDIGREE POLYTOPE AND ITS PROPERTIES

    Directory of Open Access Journals (Sweden)

    Tiru S. Arthanari

    2013-07-01

    Full Text Available The fact that linear optimization over a polytope can be done in polynomial time in the input size of the instance, has created renewed interest in studying 0-1 polytopes corresponding to combinatorial optimization problems. Studying their polyhedral structure has resulted in new algorithms to solve very large instances of some difficult problems like the symmetric traveling salesman problem. The multistage insertion formulation (MI given by the author, in 1982, for the symmetric traveling salesman problem (STSP, gives rise to a combinatorial object called the pedigree. The pedigrees are in one-to-one correspondence with Hamiltonian cycles. Given n, the convex hull of all the pedigrees is called the corresponding pedigree polytope. In this article we bring together the research done a little over a decade by the author and his doctoral students, on the pedigree polytope, its structure, membership problem and properties of the MI formulation for the STSP. In addition we summarise some of the computational and other peripheral results relating to pedigree approach to solve the STSP. The pedigree polytope possesses properties not shared by the STSP (tour polytope, which makes it interesting to study the pedigrees, both from theoretical and algorithmic perspectives.

  16. Health care access for rural youth on equal terms? A mixed methods study protocol in northern Sweden.

    Science.gov (United States)

    Goicolea, Isabel; Carson, Dean; San Sebastian, Miguel; Christianson, Monica; Wiklund, Maria; Hurtig, Anna-Karin

    2018-01-11

    The purpose of this paper is to propose a protocol for researching the impact of rural youth health service strategies on health care access. There has been no published comprehensive assessment of the effectiveness of youth health strategies in rural areas, and there is no clearly articulated model of how such assessments might be conducted. The protocol described here aims to gather information to; i) Assess rural youth access to health care according to their needs, ii) Identify and understand the strategies developed in rural areas to promote youth access to health care, and iii) Propose actions for further improvement. The protocol is described with particular reference to research being undertaken in the four northernmost counties of Sweden, which contain a widely dispersed and diverse youth population. The protocol proposes qualitative and quantitative methodologies sequentially in four phases. First, to map youth access to health care according to their health care needs, including assessing horizontal equity (equal use of health care for equivalent health needs,) and vertical equity (people with greater health needs should receive more health care than those with lesser needs). Second, a multiple case study design investigates strategies developed across the region (youth clinics, internet applications, public health programs) to improve youth access to health care. Third, qualitative comparative analysis of the 24 rural municipalities in the region identifies the best combination of conditions leading to high youth access to health care. Fourth, a concept mapping study involving rural stakeholders, care providers and youth provides recommended actions to improve rural youth access to health care. The implementation of this research protocol will contribute to 1) generating knowledge that could contribute to strengthening rural youth access to health care, as well as to 2) advancing the application of mixed methods to explore access to health care.

  17. Studies on the levels of Cs-137 originating from the Chernobyl accident in salmonid fish, its prey organisms and environment, in some alpine lakes of northern Sweden

    International Nuclear Information System (INIS)

    Hammar, J.; Neumann, G.; Notter, M.

    1988-01-01

    Fallout from the Chernobyl accident resulted in heavy surface contamination in areas of middle and northern Sweden. One of the most heavily affected regions was an approx. 5000 km 2 alpine district at the border to Norway. Shortly after the accident, the levels of Cs-137 and other radionuclides began to rise in two dominating fish species of the region, the brown trout (Salmo trutta L.) and the Arctic char (Salvelinus alpinus L. In July 1986 a research program started with the ultimate goal of understanding the mechanisms of transport for radionuclides through the food chain to fish, and, if possible, to give a forecast of the future development of the Cs-137 contamination. It comprises measurements of mainly Cs-137, Cs-134 and K-40 in 8 lakes within the area. The measurements have been performed at five occasions during the period July 1986 until October 1987. The preliminary results concerning Cs-137 show: - A large increase in levels of bottom sediments. A decrease in levels of water. A strong decrease in levels of phytoplankton, zooplankton, Gammarus and Mysis during autumn 1986, and a stabilization during 1987. In same lakes, however, another increase was recorded during 1987. That Mysis originally has the highest levels of all food items. That the levels of brown trout and Arctic char increased steadily during 1986 and showed a tendency of stabilization or slight decrease during 1987. That brown trout generally show higher levels than Arctic char and reaches its highest levels in lakes with introduced Mysis

  18. Recent invasion of the mountain birch Betula pubescens ssp. tortuosa above the treeline due to climate change: genetic and ecological study in northern Sweden.

    Science.gov (United States)

    Truong, C; Palmé, A E; Felber, F

    2007-01-01

    Mountain birch, Betula pubescens ssp. tortuosa, forms the treeline in northern Sweden. A recent shift in the range of the species associated with an elevation of the treeline is commonly attributed to climate warming. Using microsatellite markers, we explored the genetic structure of populations along an altitudinal gradient close to the treeline. Low genetic differentiation was found between populations, whereas high genetic diversity was maintained within populations. High level of gene flow compensated for possible losses of genetic diversity at higher elevations and dissipated the founding effect of newly established populations above the treeline. Spatial autocorrelation analysis showed low spatial genetic structure within populations because of extensive gene flow. At the treeline, significant genetic structure within the juvenile age class at small distances did not persist in the adult age class, indicating recent expansion of young recruits due to the warming of the climate. Finally, seedling performance above the treeline was positively correlated with parameters related to temperature. These data confirm the high migration potential of the species in response to fluctuating environmental conditions and indicate that it is now invading higher altitudes due to the recent warming of the climate.

  19. Species-specific guidelines for choosing forest regeneration material for northern Sweden; Beslutsunderlag foer val av skogsodlingsmaterial i norra Sverige med traedslagsvisa guider

    Energy Technology Data Exchange (ETDEWEB)

    Rosvall, O.; Andersson, Bengt; Ericsson, Tore

    1998-05-01

    To facilitate the selection of suitable seed-orchard and natural-stand regeneration material for sites in northern Sweden, a conceptual model was developed which includes a specification of the sites and genetic material, seed source transfer effects on various tree characters, and delineation of suitable utilization-areas for specific regeneration materials and management objectives. The most important site characteristics are photoperiod, temperature sum and local-climate pattern, specified by latitude, elevation and topography. The regeneration material is characterised by its specific properties, such as breeding value, and potential reaction to changes in the photoperiod (standardised latitudinal origin). A specification of transfer effects was made by the changes in the characteristics of a population when moved along photoperiod (latitudinal) or temperature (elevation) gradients. Optimum latitudinal seed-source transfer distances can be calculated for each temperature climate and management objective based on the economic value of the population characteristics and the species-specific transfer effects. On the basis of what were assessed to be common requirements, we drew up a baseline option whereby suitable utilization areas for seed-orchard and natural-stand progenies were delineated. An analysis was made of the consequences of the baseline option and the background information was reviewed and summarised for Pinus sylvestris, Pinus contorta, Picea abies and Betula pendula 95 refs, 24 figs, 16 tabs

  20. Using Local Event Tomography to Image Changes in the Rock Mass in the Kiirunavaara Iron Ore Mine, Northern Sweden

    Science.gov (United States)

    Lund, B.; Berglund, K.; Tryggvason, A.; Dineva, S.; Jonsson, L.

    2017-12-01

    Although induced seismic events in a mining environment are a potential hazard, they can be used to gain information about the rock mass in the mine which otherwise would be very difficult to obtain. In this study we use approximately 1.2 million mining induced seismic events in the Kiirunavaara iron ore mine in northernmost Sweden to image the rock mass using local event travel-time tomography. The Kiirunavaara mine is the largest underground iron ore mine in the world. The ore body is a magnetite sheet of 4 km length, with an average thickness of 80 m, which dips approximately 55° to the east. The events are of various origins such as shear slip on fractures, non-shear events and blasts, with magnitudes of up to 2.5. We use manually picked P- and S-wave arrival times from the routine processing in the tomography and we require that both phases are present at at least five geophones. For the tomography we use the 3D local earthquake tomography code PStomo_eq (Tryggvason et al., 2002), which we adjusted to the mining scale. The tomographic images show clearly defined regions of high and low velocities. Prominent low S-velocity zones are associated with mapped clay zones. Regions of ore where mining is ongoing and the near-ore tunnel infrastructure in the foot-wall also show generally low P- and S-velocities. The ore at depths below the current mining levels is imaged both as a low S-velocity zone but even more pronounced as a high Vp/Vs ratio zone. The tomography shows higher P- and S-velocities in the foot-wall away from the areas of mine infrastructure. We relocate all 1.2 million events in the new 3D velocity model. The relocation significantly enhances the clarity of the event distribution in space and we can much more easily identify seismically active structures, such as e.g. the deformation of the ore passes. The large number of events makes it possible to do detailed studies of the temporal evolution of stability in the mine. We present preliminary results

  1. Incidence and seasonality of falls amongst old people receiving home help services in a municipality in northern Sweden.

    Science.gov (United States)

    Vikman, Irene; Nordlund, Anders; Näslund, Annika; Nyberg, Lars

    2011-04-01

    Falls among old people is a well-documented phenomenon; however, falls among people living in the community and receiving home help services have been under-researched. The aim of this study was to investigate the incidence, including possible seasonal variation, circumstances and injuries related to falls among community living home help receivers, and to investigate whether fall incidence is associated with the type and amount of home help services received. Prospective cohort study. All 614 persons aged 65 and over who were living in a particular northern Swedish community and receiving municipality home help were included. Data on age, sex and home help service use were collected from home help service records, and falls were reported by staff on report forms specifically designed for the study. Results. A total number of 264 falls were recorded among 122 participants. The overall fall incidence was 626 per 1,000 PY, and incidence rate ratios were significantly correlated to the total amount of services used (pfalls reported as resulting in injury was 33%. The monthly fall incidence was significantly associated to daylight photoperiod, however it was not associated to temperature. Fall incidence among home help receivers aged 65 and over seems correlated to the amount of services they receive. This is probably explained by the fact that impairments connected to ADL limitations and home help needs also are connected to an increased risk of falls. This implies that fall prevention should be considered when planning home help care for old people with ADL limitations. Further research on the connection between daylight photoperiod and fall incidence in populations at different latitudes is needed.

  2. Aboveground and belowground legacies of native Sami land use on boreal forest in northern Sweden 100 years after abandonment.

    Science.gov (United States)

    Freschet, Grégoire T; Ostlund, Lars; Kichenin, Emilie; Wardle, David A

    2014-04-01

    Human activities that involve land-use change often cause major transformations to community and ecosystem properties both aboveground and belowground, and when land use is abandoned, these modifications can persist for extended periods. However, the mechanisms responsible for rapid recovery vs. long-term maintenance of ecosystem changes following abandonment remain poorly understood. Here, we examined the long-term ecological effects of two remote former settlements, regularly visited for -300 years by reindeer-herding Sami and abandoned -100 years ago, within an old-growth boreal forest that is considered one of the most pristine regions in northern Scandinavia. These human legacies were assessed through measurements of abiotic and biotic soil properties and vegetation characteristics at the settlement sites and at varying distances from them. Low-intensity land use by Sami is characterized by the transfer of organic matter towards the settlements by humans and reindeer herds, compaction of soil through trampling, disappearance of understory vegetation, and selective cutting of pine trees for fuel and construction. As a consequence, we found a shift towards early successional plant species and a threefold increase in soil microbial activity and nutrient availability close to the settlements relative to away from them. These changes in soil fertility and vegetation contributed to 83% greater total vegetation productivity, 35% greater plant biomass, and 23% and 16% greater concentrations of foliar N and P nearer the settlements, leading to a greater quantity and quality of litter inputs. Because decomposer activity was also 40% greater towards the settlements, soil organic matter cycling and nutrient availability were further increased, leading to likely positive feedbacks between the aboveground and belowground components resulting from historic land use. Although not all of the activities typical of Sami have left visible residual traces on the ecosystem after

  3. Physiotherapeutic interventions and physical activity for children in Northern Sweden with cerebral palsy: a register study from equity and gender perspectives.

    Science.gov (United States)

    Degerstedt, Frida; Wiklund, Maria; Enberg, Birgit

    Young people with disabilities, especially physical disabilities, report worse health than others. This may be because of the disability, lower levels of physical activity, and discrimination. For children with cerebral palsy, access to physiotherapy and physical activity is a crucial prerequisite for good health and function. To date, there is limited knowledge regarding potential gender bias and inequity in habilitation services. To map how physiotherapeutic interventions (PTI), physical leisure activity, and physical education are allocated for children with cerebral palsy regarding sex, age, level of gross motor function, and county council affiliation. This was done from a gender and equity perspective. A register study using data from the Cerebral Palsy follow-Up Program (CPUP). Data included 313 children ≤18 years with cerebral palsy from the five northern counties in Sweden during 2013. Motor impairment of the children was classified according to the expanded and revised Gross Motor Function Classification System (GMFCS). In three county councils, boys received more physiotherapy interventions and received them more frequently than girls did. Differences between county councils were seen for frequency and reasons for physiotherapy interventions (p children who had lower motor function and with children who had low physical leisure activity. Children with lower motor function level participated in physical leisure activity less often than children with less motor impairment (p physiotherapy interventions for children with cerebral palsy, and there are associations between gender and physical activity. Thus, the intervention is not always determined by the needs of the child or the degree of impairment. A gender-bias is indicated. Further studies are needed to ensure fair interventions.

  4. A genome scan conducted in a multigenerational pedigree with convergent strabismus supports a complex genetic determinism.

    Directory of Open Access Journals (Sweden)

    Anouk Georges

    Full Text Available A genome-wide linkage scan was conducted in a Northern-European multigenerational pedigree with nine of 40 related members affected with concomitant strabismus. Twenty-seven members of the pedigree including all affected individuals were genotyped using a SNP array interrogating > 300,000 common SNPs. We conducted parametric and non-parametric linkage analyses assuming segregation of an autosomal dominant mutation, yet allowing for incomplete penetrance and phenocopies. We detected two chromosome regions with near-suggestive evidence for linkage, respectively on chromosomes 8 and 18. The chromosome 8 linkage implied a penetrance of 0.80 and a rate of phenocopy of 0.11, while the chromosome 18 linkage implied a penetrance of 0.64 and a rate of phenocopy of 0. Our analysis excludes a simple genetic determinism of strabismus in this pedigree.

  5. A genome scan conducted in a multigenerational pedigree with convergent strabismus supports a complex genetic determinism.

    Science.gov (United States)

    Georges, Anouk; Cambisano, Nadine; Ahariz, Naïma; Karim, Latifa; Georges, Michel

    2013-01-01

    A genome-wide linkage scan was conducted in a Northern-European multigenerational pedigree with nine of 40 related members affected with concomitant strabismus. Twenty-seven members of the pedigree including all affected individuals were genotyped using a SNP array interrogating > 300,000 common SNPs. We conducted parametric and non-parametric linkage analyses assuming segregation of an autosomal dominant mutation, yet allowing for incomplete penetrance and phenocopies. We detected two chromosome regions with near-suggestive evidence for linkage, respectively on chromosomes 8 and 18. The chromosome 8 linkage implied a penetrance of 0.80 and a rate of phenocopy of 0.11, while the chromosome 18 linkage implied a penetrance of 0.64 and a rate of phenocopy of 0. Our analysis excludes a simple genetic determinism of strabismus in this pedigree.

  6. Short-rotation Willow Biomass Plantations Irrigated and Fertilised with Wastewaters. Results from a 4-year multidisciplinary field project in Sweden, France, Northern Ireland and Greece

    Energy Technology Data Exchange (ETDEWEB)

    Larsson, Stig [Svaloef Weibull AB, Svaloef (Sweden); Cuingnet, Christian; Clause, Pierre [Association pour le Developpement des Culture Energetiques, Lille (France); Jakobsson, Ingvar [Swedish Univ. of Agricultural Sciences, Uppsala (Sweden); Dawson, Malcolm [Queens Univ., Northern Ireland (United Kingdom); Backlund, Arne [A and B Backlund ApS, Charlottenlund (Denmark); Mavrogianopoulus, George [Agricultural Univ. of Athens (Greece)

    2003-01-01

    This report summarises results and experiences gathered from field trials with recycling of pre-treated wastewater, diverted human urine mixed with water, and municipal sludge, within plantations of willow species specifically selected for biomass production. Experimental sites were established in Sweden (Roma), France (Orchies), Northern Ireland (Culmore) and Greece (Larissa). The project was carried out during a 4-year period with financial support from the EU FAIR Programme. The experimental sites were supplied with primary effluent from municipal treatment plants (Culmore and Larissa), stored industrial effluent from a chicory processing plant (Orchies), biologically treated and stored municipal wastewater (Roma) and human urine mixture from diverting low-flush toilets mixed with water (Roma). Application rates of the wastewaters or the urine mixture were equivalent to the calculated evapotranspiration rate at each site. Wastewaters were also applied up to three times this value to evaluate any possible negative effects. Estimations and evaluations were carried out mainly concerning: biomass growth, potential biological attacks of the plantations, plant water requirements, fertilisation effects of the wastewater, plant uptake of nutrients and heavy metals from applied wastewater, possible soil or groundwater impact, sanitary aspects, and potentials for removal in the soil-plant filter of nutrients and biodegradable organic material from applied wastewater. The results clearly indicated that biomass production in young willow plantations could be enhanced substantially after recycling of wastewater resources. The impact on soil and groundwater of nutrients (nitrogen and phosphorus) and heavy metals (copper, zinc, lead and cadmium) was limited, even when the application of water and nutrients exceeded the plant requirements. Also, the soil-plant system seemed to function as a natural treatment filter for pre-treated (primary settled) wastewater, with a treatment

  7. Pedigree analysis of the Hungarian Thoroughbred population

    NARCIS (Netherlands)

    Bokor, A.; Jonas, D.; Ducro, B.J.; Nagy, I.; Bokor, J.; Szabari, M.

    2013-01-01

    The aim of the study was to analyse the pedigree information of Thoroughbred horses which were participating in gallop races between 1998 and 2010 in Hungary. Among the 3043 individuals of the reference population there were imported animals from foreign countries (e.g. Germany, England or Ireland)

  8. Two Search Techniques within a Human Pedigree Database

    OpenAIRE

    Gersting, J. M.; Conneally, P. M.; Rogers, K.

    1982-01-01

    This paper presents the basic features of two search techniques from MEGADATS-2 (MEdical Genetics Acquisition and DAta Transfer System), a system for collecting, storing, retrieving and plotting human family pedigrees. The individual search provides a quick method for locating an individual in the pedigree database. This search uses a modified soundex coding and an inverted file structure based on a composite key. The navigational search uses a set of pedigree traversal operations (individual...

  9. Maximum likelihood pedigree reconstruction using integer linear programming.

    Science.gov (United States)

    Cussens, James; Bartlett, Mark; Jones, Elinor M; Sheehan, Nuala A

    2013-01-01

    Large population biobanks of unrelated individuals have been highly successful in detecting common genetic variants affecting diseases of public health concern. However, they lack the statistical power to detect more modest gene-gene and gene-environment interaction effects or the effects of rare variants for which related individuals are ideally required. In reality, most large population studies will undoubtedly contain sets of undeclared relatives, or pedigrees. Although a crude measure of relatedness might sometimes suffice, having a good estimate of the true pedigree would be much more informative if this could be obtained efficiently. Relatives are more likely to share longer haplotypes around disease susceptibility loci and are hence biologically more informative for rare variants than unrelated cases and controls. Distant relatives are arguably more useful for detecting variants with small effects because they are less likely to share masking environmental effects. Moreover, the identification of relatives enables appropriate adjustments of statistical analyses that typically assume unrelatedness. We propose to exploit an integer linear programming optimisation approach to pedigree learning, which is adapted to find valid pedigrees by imposing appropriate constraints. Our method is not restricted to small pedigrees and is guaranteed to return a maximum likelihood pedigree. With additional constraints, we can also search for multiple high-probability pedigrees and thus account for the inherent uncertainty in any particular pedigree reconstruction. The true pedigree is found very quickly by comparison with other methods when all individuals are observed. Extensions to more complex problems seem feasible. © 2012 Wiley Periodicals, Inc.

  10. The hopes of West African refugees during resettlement in northern Sweden: a 6-year prospective qualitative study of pathways and agency thoughts.

    Science.gov (United States)

    Anjum, Tanvir M; Nordqvist, Cecilia; Timpka, Toomas

    2012-01-24

    Little is known about how positive phenomena can support resettlement of refugees in a new country. The aim of this study was to examine the hopeful thinking in a group of West African quota refugees at arrival and after 6 years in Sweden and compare these thoughts to the views of resettlement support professionals. The primary study population comprised 56 adult refugees and 13 resettlement professionals. Qualitative data were collected from the refugees by questionnaires on arrival and 6 years later. Data were collected from the resettlement professionals by interview about 3 years after arrival of the refugees. Snyder's cognitive model of hope was used to inform the comparative data analyses. Hopes regarding education were in focus for the refugees shortly after arrival, but thoughts on family reunion were central later in the resettlement process. During the later stages of the resettlement process, the unresponsiveness of the support organization to the family reunion problem became as issue for the refugees. The professionals reported a complex mix of "silent agency thoughts" underlying the local resettlement process as a contributing reason for this unresponsiveness. Hopes regarding education and family reunion were central in the resettlement of West African refugees in Sweden. These thoughts were not systematically followed up by the support organization; possibly the resources for refugees were not fully released. More studies are needed to further investigate the motivational factors underpinning host community support of refugees' hopes and plans.

  11. The hopes of West African refugees during resettlement in northern Sweden: a 6-year prospective qualitative study of pathways and agency thoughts

    Directory of Open Access Journals (Sweden)

    Anjum Tanvir M

    2012-01-01

    Full Text Available Abstract Background Little is known about how positive phenomena can support resettlement of refugees in a new country. The aim of this study was to examine the hopeful thinking in a group of West African quota refugees at arrival and after 6 years in Sweden and compare these thoughts to the views of resettlement support professionals. Method The primary study population comprised 56 adult refugees and 13 resettlement professionals. Qualitative data were collected from the refugees by questionnaires on arrival and 6 years later. Data were collected from the resettlement professionals by interview about 3 years after arrival of the refugees. Snyder's cognitive model of hope was used to inform the comparative data analyses. Results Hopes regarding education were in focus for the refugees shortly after arrival, but thoughts on family reunion were central later in the resettlement process. During the later stages of the resettlement process, the unresponsiveness of the support organization to the family reunion problem became as issue for the refugees. The professionals reported a complex mix of "silent agency thoughts" underlying the local resettlement process as a contributing reason for this unresponsiveness. Conclusion Hopes regarding education and family reunion were central in the resettlement of West African refugees in Sweden. These thoughts were not systematically followed up by the support organization; possibly the resources for refugees were not fully released. More studies are needed to further investigate the motivational factors underpinning host community support of refugees' hopes and plans.

  12. Nuclear Pedigree Criteria of Suspected HNPCC

    Directory of Open Access Journals (Sweden)

    Kładny Józef

    2003-01-01

    Full Text Available Abstract The criteria for the diagnosis of HNPCC established by the ICG-HNPCC are very restrictive as they do not allow for the diagnosis of a large number of "suspected HNPCC" cases - these are families which do no fulfill the strict diagnostic "Amsterdam criteria", but do present with several pedigree and clinical features characteristic for HNPCC. Several series of families suspected of harboring germline mutations in DNA mismatch repair genes have been studied for germline changes in DNA mismatch repair genes and a mutation rate of somewhere between 8-60% was found. Therefore a subgroup of members of the ICG-HNPCC has been working on pedigree/clinical diagnostic criteria for suspected HNPCC. Materials and methods Part I The study was based on two series of colorectal cancer (CRC cases: 1 HNPCC - this group comprised 190 patients affected by CRC from randomly selected families which fulfilled the Amsterdam II criteria registered in Düsseldorf, Germany (102 cases of CRC, Denmark (18 CRCs, Leiden, Holland (23 CRCs and Szczecin, Poland (47 CRCs. 2 Consecutive CRCs - this group comprised 629 (78.0% of 806 individuals with CRC diagnosed in 1991-1997 in the city of Szczecin (ca. 400,000 of inhabitants, Poland. Nuclear pedigrees in both groups were compared for frequency of occurrence of clinical features, that have been shown to be associated with HNPCC. Part II 52 consecutive CRC cases from Szczecin, matching the criteria recognized in part I as appropriate for diagnosis of cases "suspected of HNPCC" were studied for the occurrence of germline hMSH2/hMLH1 constitutional mutations using "exon by exon" sequencing. Results The combination of features - i.e. the occurrence of an HNPCC associated cancer (CRC or cancer of the endometrium, small bowel or urinary tract in a 1st degree relative of a CRC patient; at least one of the patients being diagnosed under age of 50 - appeared to be strongly associated to HNPCC with an OR - 161. Constitutional

  13. Sweden's help

    International Nuclear Information System (INIS)

    1969-01-01

    The Government of Sweden has decided to provide funds for the Agency to use for agreed projects in developing countries, and the Board of Governors has authorized the Director General to conclude an agreement to bring the scheme into effect. The Agency will administer the funds and will select and process requests to be considered for their use; it will also be responsible for project supervision and control. Responsibility for implementing the agreement on behalf of the Swedish Government is entrusted to the Swedish International Development Authority (SIDA) which functions under the auspices of the Ministry of Foreign Affairs and administers Swedish bilateral technical, financial and humanitarian assistance. SIDA has already provided, or has agreed to provide, assistance for a number of Agency technical co-operation programmes and for the International Centre for Theoretical Physics in Trieste. (author)

  14. The effect of temperature on forest production in Canada, Finland and Sweden. Predicted effects of a global warming on production of lodgepole pine and Scots pine in the northern boreal forest

    International Nuclear Information System (INIS)

    Fries, Anders

    1998-01-01

    The aims of this study were to analyse relationships between forest production and climatic factors under different biogeoclimatic conditions and, thus, to enhance our ability to predict changes in production following temperature increases. Production in the IUFRO 70/71 provenance test series with lodgepole pine (Pinus contorta var. latifolia) was correlated to climate data from adjacent meteorological stations. Field-tests in Canada (British Columbia and the Yukon) and Scandinavia (Finland and Sweden) were evaluated about 20 years after planting. The temperature regime was strongly correlated to forest production in the northern boreal forest regions. The temperature during the growing season as a whole and the length of it seem to be more important than the maximum summer temperature. The relationship between production and temperature was weaker in Canada than in Scandinavia, and production increased generally more on poor and intermediate sites than on rich sites. According to the presented algorithms, an increase in the temperature sum from 600 to 1200 degree days, would theoretically result in an increase in site index of between 5 and 13 m for lodgepole pine, and slightly lower for Scots pine. The highest increases would occur in Scandinavia. Temperature plots show that, especially in northern Scandinavia, a higher mean temperature would prolong the growing season, and this may make short spells with above 0 deg C-temperatures during the dormant period. Together with drought during the growing season, this may increase the frequency of climate-related frost damage

  15. Can physicians be replaced with gynecological teaching women to train medical students in their first pelvic examination? A pilot study from Northern Sweden.

    Science.gov (United States)

    Grankvist, Olov; Olofsson, Anders D; Isaksson, Rose-Marie

    2014-07-01

    The main objective was to gain a deeper understanding of how medical students perceive and experience learning from gynecological teaching women (GTW) instead of physicians in their first pelvic examination. A second aim was to describe how the women experience their roles as GTW. Data were collected from individual interviews with 24 medical students from a medical school in Sweden and with 5 GTW. Discourse analysis was performed to acquire a deeper understanding of the informants' experiences and to understand social interactions. Five themes revealed in the medical students' experiences: "Hoping that anxiety will be replaced with security," "Meeting as equals creates a sense of calm," "Succeeding creates a sense of security for the future," "Wanting but not having the opportunity to learn more," and "Feeling relieved and grateful." One theme revealed in the GTW experiences: "Hoping to relate in a trustworthy way." To replace physicians with GTW may facilitate the learning process and may also help medical students improve their communicative skills. Using GTW will hopefully further improve students' basic medical examination techniques and physician-patient relationships. Since GTW seems to increase self-confidence and skills of medical students performing their first pelvic examination we recommend that the use of GTW is considered in the training of medical students. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  16. pedigreejs: a web-based graphical pedigree editor.

    Science.gov (United States)

    Carver, Tim; Cunningham, Alex P; Babb de Villiers, Chantal; Lee, Andrew; Hartley, Simon; Tischkowitz, Marc; Walter, Fiona M; Easton, Douglas F; Antoniou, Antonis C

    2018-03-15

    The collection, management and visualization of clinical pedigree (family history) data is a core activity in clinical genetics centres. However, clinical pedigree datasets can be difficult to manage, as they are time consuming to capture, and can be difficult to build, manipulate and visualize graphically. Several standalone graphical pedigree editors and drawing applications exist but there are no freely available lightweight graphical pedigree editors that can be easily configured and incorporated into web applications. We developed 'pedigreejs', an interactive graphical pedigree editor written in JavaScript, which uses standard pedigree nomenclature. Pedigreejs provides an easily configurable, extensible and lightweight pedigree editor. It makes use of an open-source Javascript library to define a hierarchical layout and to produce images in scalable vector graphics (SVG) format that can be viewed and edited in web browsers. The software is freely available under GPL licence (https://ccge-boadicea.github.io/pedigreejs/). tjc29@cam.ac.uk. Supplementary data are available at Bioinformatics online.

  17. Meddling with middle modalities: a decomposition approach to mental health inequalities between intersectional gender and economic middle groups in northern Sweden

    Directory of Open Access Journals (Sweden)

    Per E. Gustafsson

    2016-11-01

    Full Text Available Background: Intersectionality has received increased interest within population health research in recent years, as a concept and framework to understand entangled dimensions of health inequalities, such as gender and socioeconomic inequalities in health. However, little attention has been paid to the intersectional middle groups, referring to those occupying positions of mixed advantage and disadvantage. Objective: This article aimed to 1 examine mental health inequalities between intersectional groups reflecting structural positions of gender and economic affluence and 2 decompose any observed health inequalities, among middle groups, into contributions from experiences and conditions representing processes of privilege and oppression. Design: Participants (N=25,585 came from the cross-sectional ‘Health on Equal Terms’ survey covering 16- to 84-year-olds in the four northernmost counties of Sweden. Six intersectional positions were constructed from gender (woman vs. men and tertiles (low vs. medium vs. high of disposable income. Mental health was measured through the General Health Questionnaire-12. Explanatory variables covered areas of material conditions, job relations, violence, domestic burden, and healthcare contacts. Analysis of variance (Aim 1 and Blinder-Oaxaca decomposition analysis (Aim 2 were used. Results: Significant mental health inequalities were found between dominant (high-income women and middle-income men and subordinate (middle-income women and low-income men middle groups. The health inequalities between adjacent middle groups were mostly explained by violence (mid-income women vs. men comparison; material conditions (mid- vs. low-income men comparison; and material needs, job relations, and unmet medical needs (high- vs. mid-income women comparison. Conclusions: The study suggests complex processes whereby dominant middle groups in the intersectional space of economic affluence and gender can leverage strategic

  18. Comparison of association mapping methods in a complex pedigreed population

    DEFF Research Database (Denmark)

    Sahana, Goutam; Guldbrandtsen, Bernt; Janss, Luc

    2010-01-01

    to collect SNP signals in intervals, to avoid the scattering of a QTL signal over multiple neighboring SNPs. Methods not accounting for genetic background (full pedigree information) performed worse, and methods using haplotypes were considerably worse with a high false-positive rate, probably due...... to the presence of low-frequency haplotypes. It was necessary to account for full relationships among individuals to avoid excess false discovery. Although the methods were tested on a cattle pedigree, the results are applicable to any population with a complex pedigree structure...

  19. High-Resolution Remote Sensing and Stable Isotope Patterns Across Heath-Shrub-Forest Ecotone at Abisko and Vassijaure, Northern Sweden

    Science.gov (United States)

    Schwan, M. R.; Herrick, C.; Hobbie, E. A.; Chen, J.; Varner, R. K.; Palace, M. W.; Marek, E.; Kashi, N. N.; Smith, S. L.

    2015-12-01

    Rapid warming in arctic and sub-arctic environments shifts plant community structure which in turn can alter carbon cycling by releasing large stocks of carbon sequestered in arctic soils. Much work has been done in sub-arctic peatlands to understand how shifts in dominant vegetation cover can ultimately affect global carbon balances, but less focus has been given to upland environments where similar changes are occurring. Recent circumpolar expansion of deciduous shrubs and trees in sub-arctic upland environments may alter carbon cycling due to shrubs and trees sequestering less C in soils than the heath plants they typically replace. In this study we explored the relationship between nutrient and carbon cycling and above-ground vegetation on six transects which traverse an ecotone gradient from heath tundra (dominated by ericoid mycorrhizal plants) through deciduous shrubs to deciduous trees (dominated by ectomycorrhizal plants) in upland environments of sub-arctic Sweden near Vassijaure (~850 mm precipitation) and Abisko (~300 mm precipitation). We collected soil and foliage for analysis of natural abundances of stable carbon and nitrogen isotopes (δ13C and δ15N), which can be a sensitive indicator of C and N dynamics. We also took high-resolution remote aerial imagery over the transects to calculate percent cover of vegetation types using GIS software. We concurrently estimated percent cover in smaller plots on the ground of three dominant species, Empetrum nigrum, Betula nana, and Betula pubescens, to serve as ground-truthing for the aerial imagery. Analysis of vegetation cover data shows significant differences in vegetation types along the transects. Preliminary multiple regression analysis of isotopes shows that δ13C in organic soil at the Vassijaure site is mostly controlled by distance along the transect, an interaction term between transect distance and soil depth, and δ15N (adjusted r2 = 0.85, p regression analyses, δ15N was primarily controlled by

  20. Post-glacial faulting in the Lansjaerv area, Northern Sweden. Comments from the expert group on a field visit at the Molberget post-glacial fault area, 1991

    International Nuclear Information System (INIS)

    Stanfors, R.; Ericsson, L.O.

    1993-05-01

    Post-glacial faults have been recognized in the northern Baltic shield for several decades. It is important to evaluate whether such neotectonic movements can lead to new fracturing or decisively alter the geohydrological or geohydrochemical situation around a final repository for spent nuclear fuel. The post-glacial Lansjaerv fault was chosen for an interdisciplinary study because of its relative accessibility. The goals of the study were to assess the mechanisms that caused present day scraps, to clarify the extent of any recent fracturing and to clarify the extent of any ongoing movements. All these objectives were reasonably met through a series of studies, which have been performed by SKB during 1986-1992 in two phases. This report gives a summary of the first phase of the Lansjaerv study (1986-1989) and describes achievements that have been gained during the second phase of the study. As a final of the field-work in the Lansjaerv area a meeting combined with a field excursion was arranged by SKB in June 1991 for a group of international experts. Comments from the expert group on the excursion and the overall Lansjaerv project are presented. One of the major conclusions is that the Lansjaerv post-glacial fault reactivated pre-existing old structures and that the causes of the post-glacial movements is a combination of plate tectonics and deglaciation

  1. Policing football in Sweden

    DEFF Research Database (Denmark)

    Stott, Clifford; Havelund, Jonas; Lundberg, Filip

    2016-01-01

    of football policing in Sweden. Central to these is the empowerment and coordination of dialogue based approaches to the policing of football supporters in Sweden. The report points out that this is an area of crowd policing where Sweden are global leaders having influenced how policing is conducted in other...

  2. Pedigree Analysis of Holstein Bulls in Slovakia

    Directory of Open Access Journals (Sweden)

    Ivan Pavlík

    2012-05-01

    Full Text Available The aim of the study was to evaluate the genetic diversity in Holstein bulls population in Slovakia by the methods of pedigree analysis. The population was represented by the bulls with reserve of frozen semen doses in AI centers. Whole reference population consisted of 169 bulls born from 1997 to 2009. For calculation of diversity parameters the program Endog v.4.8 (Gutiérrez, Goyache, 2005 was used. An average maximal number of generations traced was 9.35, 3.06 complete generations and equivalent number of generations traced was 5.71. An average coefficient of inbreeding was 2.48%, individual increase in inbreeding was 0.53% and average relatedness was 2.72%. The 167 bulls from 169 were inbred (98.82%. An average number of offsprings per bull was 107.70 with maximal number 1,641 offsprings. The effective population size computed via individual increase in inbreeding was 94.50. The effective number of founders was 88, effective number of ancestors 31 and only 13 ancestors described 50% of diversity. From these results we can conclude that the diversity of Holstein bulls is reduced by more factors (inbreeding, high relatedness, bottlenecks. Obtained results point out the need to use new outbred bull lines for mating cows.

  3. Exome sequencing of a multigenerational human pedigree.

    Directory of Open Access Journals (Sweden)

    Dale J Hedges

    2009-12-01

    Full Text Available Over the next few years, the efficient use of next-generation sequencing (NGS in human genetics research will depend heavily upon the effective mechanisms for the selective enrichment of genomic regions of interest. Recently, comprehensive exome capture arrays have become available for targeting approximately 33 Mb or approximately 180,000 coding exons across the human genome. Selective genomic enrichment of the human exome offers an attractive option for new experimental designs aiming to quickly identify potential disease-associated genetic variants, especially in family-based studies. We have evaluated a 2.1 M feature human exome capture array on eight individuals from a three-generation family pedigree. We were able to cover up to 98% of the targeted bases at a long-read sequence read depth of > or = 3, 86% at a read depth of > or = 10, and over 50% of all targets were covered with > or = 20 reads. We identified up to 14,284 SNPs and small indels per individual exome, with up to 1,679 of these representing putative novel polymorphisms. Applying the conservative genotype calling approach HCDiff, the average rate of detection of a variant allele based on Illumina 1 M BeadChips genotypes was 95.2% at > or = 10x sequence. Further, we propose an advantageous genotype calling strategy for low covered targets that empirically determines cut-off thresholds at a given coverage depth based on existing genotype data. Application of this method was able to detect >99% of SNPs covered > or = 8x. Our results offer guidance for "real-world" applications in human genetics and provide further evidence that microarray-based exome capture is an efficient and reliable method to enrich for chromosomal regions of interest in next-generation sequencing experiments.

  4. Partitioning of copy-number genotypes in pedigrees

    Directory of Open Access Journals (Sweden)

    Andelfinger Gregor U

    2010-05-01

    Full Text Available Abstract Background Copy number variations (CNVs and polymorphisms (CNPs have only recently gained the genetic community's attention. Conservative estimates have shown that CNVs and CNPs might affect more than 10% of the genome and that they may be at least as important as single nucleotide polymorphisms in assessing human variability. Widely used tools for CNP analysis have been implemented in Birdsuite and PLINK for the purpose of conducting genetic association studies based on the unpartitioned total number of CNP copies provided by the intensities from Affymetrix's Genome-Wide Human SNP Array. Here, we are interested in partitioning copy number variations and polymorphisms in extended pedigrees for the purpose of linkage analysis on familial data. Results We have developed CNGen, a new software for the partitioning of copy number polymorphism using the integrated genotypes from Birdsuite with the Affymetrix platform. The algorithm applied to familial trios or extended pedigrees can produce partitioned copy number genotypes with distinct parental alleles. We have validated the algorithm using simulations on a complex pedigree structure using frequencies calculated from a real dataset of 300 genotyped samples from 42 pedigrees segregating a congenital heart defect phenotype. Conclusions CNGen is the first published software for the partitioning of copy number genotypes in pedigrees, making possible the use CNPs and CNVs for linkage analysis. It was implemented with the Python interpreter version 2.5.2. It was successfully tested on current Linux, Windows and Mac OS workstations.

  5. Country report: Sweden

    International Nuclear Information System (INIS)

    1993-01-01

    Sweden has twelve nuclear power reactors with a combined capacity of 9900 MW net electric power. According to a resolution passed by parliament in 1980, Sweden will terminate its use of nuclear power in the year 2010, at the latest. According to generally accepted guidelines, the spent nuclear fuel will be kept in interim storage for approximately 40 years after which, according to present plans, it will be deposited in geological formations in Sweden

  6. Soil pH and nutrient uptake in cauliflower (Brassica oleracea L. var. botrytis) and Broccoli (Brassica oleracea L. var. italica) in Northern Sweden. Multielement studies by means of plant and soil analyses

    Energy Technology Data Exchange (ETDEWEB)

    Magnusson, Margareta [Swedish Univ. of Agricultural Sciences, Umeaa (Sweden). Dept. of Agricultural Research for Northern Sweden

    2000-07-01

    To reveal nutrient element deficiencies or imbalances limiting vegetable production in northern Sweden, multielement soil and plant analyses were performed in cauliflower and broccoli during the period 1989 to 1996. The pH range of the soils was 4.4-8. 1. The results were evaluated with the multivariate statistical methods PCA (Principal Component Analysis) and PLS (Partial Least Squares Projection to Latent Structures). The major yield-limiting elements were Mg, B, Mn, Zn, Fe and Cu. This was a result of high soil pH and large content of Ca in the soil. The reason for B deficiency was also low B content in the soil. Applications of green mulch increased yield on soils with a pH below 6.0. It also increased the uptake and concentration in the plants of B, Ba, Cl, Cu, K, Mg, Mn, N, P, Se and Zn, and decreased the uptake and concentration of Al, Cs and Tl. The mineral fertilizer applied, NPK 11-5-18 micro, decreased soil pH. This has resulted in larger uptake and higher concentrations in the plants of Co and Mn, in comparison to where cattle manure was applied. This fertilizer strongly decreased uptake of Mo, as a result of both the acidifying effect and the large S content. Repeated applications of nitrate of lime in combination with the NPK 11-5-18 strongly increased the uptake of Cs by the plants. The results in this investigation, together with the literature reviews, strongly indicate that a relatively low soil pH (5.0-5.5) is favourable when organic fertilizers are used and that harmful effects of very low soil pH (<5.0), are ameliorated by organic materials but aggravated by mineral fertilizers. The main purpose of lime is to counteract the acidity and increased leaching created by mineral fertilizers. Because of the historical context in which the lime requirements were established, the dangers of acid soils appear to have been strongly overestimated.

  7. Lone mothers in Sweden

    DEFF Research Database (Denmark)

    Burström, B; Diderichsen, Finn; Shouls, S

    1999-01-01

    To study trends in the health and socioeconomic circumstances of lone mothers in Sweden over the years 1979-1995, and to make comparisons with couple mothers over the same period.......To study trends in the health and socioeconomic circumstances of lone mothers in Sweden over the years 1979-1995, and to make comparisons with couple mothers over the same period....

  8. Energy in Sweden 2010

    Energy Technology Data Exchange (ETDEWEB)

    2010-11-15

    The annual Energy in Sweden report, and its sister publication, Energy in Sweden - Facts and Figures 2010 (STEM-ET--2010-46), are intended to provide decision makers, journalists, companies, teachers and the public with coherent and easily available information on developments in the energy sector. Most of the publication is based on official statistics up to and including 2009, complemented where possible by input reflecting current events and decisions up to the middle of 2010. Energy in Sweden presents facts about the use and supply of energy, present energy- and climate policy and policy measures, energy prices and energy markets, the impact of energy systems on the environment and an international outlook etc. See also the publication Energy in Sweden - Facts and Figures 2010 where the tabular data behind most of the diagrams in Energy in Sweden are presented

  9. Energy in Sweden 2009

    Energy Technology Data Exchange (ETDEWEB)

    2009-12-15

    The annual Energy in Sweden report, and its sister publication, Energy in Sweden: Facts and Figures (STEM-ET--2009-29), are intended to provide decision makers, journalists, companies, teachers and the public with coherent and easily available information on developments in the energy sector. Most of the publication is based on official statistics up to and including 2008, complemented where possible by input reflecting current events and decisions up to the middle of 2009. Energy in Sweden presents facts about the use and supply of energy, present energy- and climate policy and policy measures, energy prices and energy markets, the impact of energy systems on the environment and an international outlook etc. See also the publication Energy in Sweden - Facts and Figures 2009 where the tabular data behind most of the diagrams in Energy in Sweden are presented

  10. Checking Consistency of Pedigree Information is NP-complete

    DEFF Research Database (Denmark)

    Aceto, Luca; Hansen, Jens A.; Ingolfsdottir, Anna

    Consistency checking is a fundamental computational problem in genetics. Given a pedigree and information on the genotypes of some of the individuals in it, the aim of consistency checking is to determine whether these data are consistent with the classic Mendelian laws of inheritance. This probl...

  11. Cadmium in Sweden - environmental risks

    Energy Technology Data Exchange (ETDEWEB)

    Parkman, H; Iverfeldt, Aa [Swedish Environmental Research Inst. (Sweden); Borg, H; Lithner, G [Stockholm Univ. (Sweden). Inst. for Applied Environmental Research

    1998-03-01

    This report aims at assessing possible effects of cadmium in the Swedish environment. Swedish soils and soft freshwater systems are, due to a generally poor buffering capacity, severely affected by acidification. In addition, the low salinity in the Baltic Sea imply a naturally poor organism structure, with some important organisms living close to their limit of physiological tolerance. Cadmium in soils is mobilized at low pH, and the availability and toxicity of cadmium in marine systems are enhanced at low salinity. The Swedish environment is therefore extra vulnerable to cadmium pollution. The average concentrations of cadmium in the forest mor layers, agricultural soils, and fresh-waters in Sweden are enhanced compared to `back-ground concentrations`, with a general increasing trend from the north to the south-west, indicating strong impact of atmospheric deposition of cadmium originating from the central parts of Europe. In Swedish sea water, total cadmium concentrations, and the fraction of bio-available `free` cadmium, generally increases with decreasing salinity. Decreased emissions of cadmium to the environment have led to decreasing atmospheric deposition during the last decade. The net accumulation of cadmium in the forest mor layer has stopped, and even started to decrease. In northern Sweden, this is due to the decreased deposition, but in southern Sweden the main reason is increased leakage of cadmium from the topsoil as a consequence of acidification. As a result, cadmium in the Swedish environments is undergoing an extended redistribution between different soil compartments, and from the soils to the aquatic systems. 90 refs, 23 figs, 2 tabs. With 3 page summary in Swedish

  12. Linnaeus in Uppsala, Sweden.

    Science.gov (United States)

    Cohen, Paul; Cohen, Brenda

    1997-01-01

    Presents a brief life history of Carl Linnaeus, a professor of medicine and botany in Uppsala, Sweden. Highlights his work in developing a classification system for plants and animals, and his botanical lectures and demonstrations. (JRH)

  13. The bedrock and the soil types in the Finnsjoearea, Sweden

    International Nuclear Information System (INIS)

    Almen, K.-E.; Ekman, L.; Olkiewicz, A.

    1978-11-01

    This report is a part of a long-term project, started at the request of the Nuclear Fuel Safety Project, Sweden. The aim of the project is to claryfy the geohydrological situation of a drainage area close to Finnsjoen in northern Uppland, Sweden. The work comprised bedrock- and soil mapping as well as an investigation of existing literature about the geology of northern Uppland. The area is about 25 km 2 and is limited by its water-shed. The area is relatively flat, rich in outcrops - expecially in the western parts - and often swampy. Big areas of forests and agriculture have been drained by ditches. (author)

  14. Radiological physics in Sweden

    International Nuclear Information System (INIS)

    Walstam, Rune

    1980-01-01

    Development of radiological or radiation physics as a separate discipline in Sweden is outlined. Growth in number of hospital physicists is compared with that of some other countries for the period 1950-1975. The main duties of hospital physicists are described. Undergraduate and postgraduate courses in radiation physics in Sweden are discussed. A microtron and a multi-source cobalt-60 unit are described. (M.G.B.)

  15. Kabbalah in Sweden

    Directory of Open Access Journals (Sweden)

    Thomas Karlsson

    2008-01-01

    Full Text Available This article examines the history of Kabbalah in Sweden. The reader is presented with an overall view to Kabbalah in Sweden: first, the Johannes Bureus and the Nordic Kabbalah, Kabbalah after Bureus, Kabbalistic literature, and last, Kabbalah in Sweden today. When the Kabbalah reached Sweden it was mainly the non-Jewish Kabbalah that gained influence, even if its Jewish roots were acknowledged. Johannes Bureus unites, in a similar fashion as do the Christian Kabbalists in continental Europe, Christian motifs with the symbolic world of the Kabbalah. Bureus, however, adds runes, ancient Norse gods and Gothic ideas in his own unique manner. The Kabbalah invites speculation and the search for correspondences which has caused the Kabbalah in Sweden to be united with a number of other traditions. Bureus combined the Kabbalah with runes and Gothicism; in the eighteenth and nineteenth centuries we can find the Kabbalah in Freemasonry and Esoteric societies, while the Kabbalah in the twentieth century and onwards has been associated with New Age, Parapsychology and Indian Mysticism. Apart from Bureus, most Kabbalists in Sweden have followed the trends that flourished in the rest of the world. Bureus was the first to create a specifically Swedish interpretation of the Kabbalah.

  16. Did the Kiruna iron ores form as a result of a metasomatic or igneous process? New U-Pb and Nd data for the iron oxide apatite ores and their host rocks in the Norrbotten region of northern Sweden

    Science.gov (United States)

    Westhues, A.; Hanchar, J. M.; Whitehouse, M. J.; Fisher, C. M.

    2012-12-01

    A number of iron deposits near Kiruna in the Norrbotten region of northern Sweden are of the iron oxide apatite (IOA) type of deposits; also referred to as Kiruna-type deposits. They are commonly considered a subgroup or end-member of iron oxide copper gold (IOCG) deposits, containing no economic grades of copper or gold. Both IOCG and IOA deposits are characterized by abundant low-Ti Fe oxides, an enrichment in REE, and intense sodium and potassium wall-rock alteration adjacent to the ores. Deposits of these types are of a great economic importance, not only for iron, but also for other elements such as rare earth elements (REE) or uranium. Kiruna, the type locality of the IOA type of mineral deposits, is the focus of this study. Despite a century-long mining history and 2500 Mt of iron ore produced in the region to date (with grades of 30 to 70 wt.% Fe), the genesis of these deposits is poorly understood: theories of a magmatic vs. a hydrothermal or metasomatic origin have been debated, and the timing of mineralization of the ores in the Norbotten region has never been directly dated. The results anticipated from this study will provide a better understanding of the nature of the IOA type of mineral deposits and their relation to IOCG deposits such as Olympic Dam in Australia. An array of geochemical methods is used in order to gain insights on the emplacement history of the host rocks, their subsequent alteration, and the ore genesis of these deposits. This includes in situ U/Pb geochronology of zircon, monazite, and titanite to constrain the timing between host rock emplacement, alteration and mineralization. Isotopic data from whole rocks and in situ at mineral scale will provide constraints on the involvement of hydrothermal fluids and their possible sources, as well as on the sources of Fe, U, and the REE. Newly obtained Sm-Nd isotopic data points to distinct source differences between host rocks, ore and alteration related samples. Preliminary in situ U

  17. Familial atrophia maculosa varioliformis cutis: case report and pedigree analysis.

    Science.gov (United States)

    Qu, T; Wang, B; Fang, K

    2005-10-01

    Atrophia maculosa varioliformis cutis (AVMC) was first described in 1918, as a rarely reported form of idiopathic macular atrophy on the cheeks. Nineteen patients have been reported in the past 86 years. Recently we diagnosed a 25-year-old woman as AMVC and investigated her family history. We collected the clinical data of the pedigree and presumed that AVMV is in a autosomal dominant inheritance.

  18. Clinical features and genetic analysis of tuberous sclerosis pedigrees

    Directory of Open Access Journals (Sweden)

    LI Ya-qin

    2012-06-01

    Full Text Available Objective In order to understand tuberous sclerosis complex better, the clinical manifestation, imaging characteristics, and genetic characteristics of tuberous sclerosis complex from 3 pedigrees were investigated. Methods The clinical data of patients from 3 tuberous sclerosis families were collected. The gene mutation type of TSC2 of proband in pedigree one was determined by PCR and direct gene sequencing. Results All of the 3 probands went to our clinic for the reason of epilepsy. Brain imaging examination noted intracranial nodular calcification. EEG showed comprehensive spines and slow waves, sharp waves. The pedigree 1 has family history, two male patients and 3 female patients, all had facial angiofibromas and epilepsy. Gene mutation analysis of TSC2 demonstrated the c.1444-2A > C mutation in index patient. All the 3 index patients had mental retardation, autism and hypopigmented macule. Conclusion For infants and young children with epilepsy as the first symptom, accompanied by mental retardation, autism, facial angiofibromas or hypopigmented macule and other skin abnormalities, brain imaging examination noted intracranial nodular calcification are highly suggestive of tuberous sclerosis complex. TSC1 and TSC2 gene analysis contribute to the diagnosis of this disease, genentic counseling and prenatal diagnosis.

  19. Energy in Sweden 2008

    Energy Technology Data Exchange (ETDEWEB)

    2008-12-15

    Energy in Sweden is published annually and is intended to provide decision-makers, journalists, companies, teachers and the general public with a coherent and easily available source of information on developments in the energy sector. Statistics are presented up to and including year 2007, when possible. Energy in Sweden presents facts about the use and supply of energy, present energy- and climate policy and policy measures, energy prices and energy markets, the impact of energy systems on the environment, and an international outlook. A new chapter for this year is Secure energy supply. There is also a chapter on Sweden's share of renewable energy calculated with the definition by the European commission. See also the publication Energy in Sweden - Facts and Figures 2008 where the tabular data behind most of the diagrams in Energy in Sweden are presented. Most of the publication is based on official statistics up to and including 2007, complemented where possible by input reflecting current events and decisions up to the middle of 2008

  20. The Enhanced Radiocaesium Levels of People in Northern Sweden; Charge Corporelle de Radiocesium Relativement Elevie chez les Habitants de la Suede Septentrionale; 041f 041e 0414 0 ; Cargas de Radiocesio Anormalmente Elevadas en los Habitantes del Norte de Suecia

    Energy Technology Data Exchange (ETDEWEB)

    Liden, K.; Naversten, Y. [Radiation Physics Department, University of Lund (Sweden)

    1964-11-15

    After the discovery of the high caesium-137 body activity of Swedish Lapps early in 1961 measurements were performed on large groups of Lapps and other Swedes on a similar diet. In September, 1961 162 persons from an area close to the arctic circle were measured in a semi-portable whole-body counter. In the Lapp group caesium-137 levels ranging from 15 to 690 nc were found. At the same place a group of 157 persons were counted in April, 1962. At that time the caesium-137 range was 30 to 740 nc. During a five weeks expedition to seven different centres in northern Sweden in April, 1963 a total number of 458 persons were studied by means of the same counter set up in a bus. The caesium-137 range for Lapps in the above mentioned area was then 50 to 900 nc. The average caesium-137 body activity of all the adult male reindeer breeders (78 persons) measured in April, 1963 was 461 nc. The maximum body activity found was 1340 nc caesium-137. Details are presented on the variation of caesium-137 in human beings with age, sex, occupation and diet as well as on the seasonal and geographical variations found. An increase in the average caesium-137 body activity has been observed from 1961 to 1963. For comparison, non-Lapps have also been counted. Almost all of them also show a substantially enhanced caesium-137 level if compared with persons in southern Sweden. The radiation dose from caesium-137 is in many cases two to three times as large as the potassium-40 dose, the observed maximum giving a dose eight times that of the potassium dose. (author) [French] Lorsqu'on eut decouvert au debut de 1961 que la charge corporelle de cesium 137 etait elevee chez les Lapons de Suede, on a fait des dosages sur des groupes importants de Lapons et d'autres habitants de la Suede qui suivent un regime alimentaire analogue. En septembre 1961, on a effectue des dosages sur 162 personnes d'une region situee a proximite du cercle arctique au moyen d'un anthropogammametre semi- portatif. Chez les

  1. Energy in Sweden 2007

    Energy Technology Data Exchange (ETDEWEB)

    2007-11-15

    Energy in Sweden is published annually, and is intended to provide decision-makers, journalists and the public with coherent and easily available information on developments in the energy sector. Most of the publication is based on official statistics up to and including 2006, complemented where possible by input reflecting current events and decisions up to the middle of 2007. The publication consists of eight chapters: Current energy and climate policy areas; Policy measures and incentives; Sweden's energy balance; Energy use; Energy markets; An international perspective; The environmental situation; and, Energy facts

  2. Energy in Sweden 2007

    Energy Technology Data Exchange (ETDEWEB)

    2007-11-15

    Energy in Sweden is published annually, and is intended to provide decision-makers, journalists and the public with coherent and easily available information on developments in the energy sector. Most of the publication is based on official statistics up to and including 2006, complemented where possible by input reflecting current events and decisions up to the middle of 2007. The publication consists of eight chapters: Current energy and climate policy areas; Policy measures and incentives; Sweden's energy balance; Energy use; Energy markets; An international perspective; The environmental situation; and, Energy facts

  3. VIPER:a visualisation tool for exploring inheritance inconsistencies in genotyped pedigrees

    OpenAIRE

    Paterson, Trevor; Graham, Martin; Kennedy, Jessie; Law, Andy

    2012-01-01

    Background Pedigree genotype datasets are used for analysing genetic inheritance and to map genetic markers and traits. Such datasets consist of hundreds of related animals genotyped for thousands of genetic markers and invariably contain multiple errors in both the pedigree structure and in the associated individual genotype data. These errors manifest as apparent inheritance inconsistencies in the pedigree, and invalidate analyses of marker inheritance patterns across the dataset. Cleaning ...

  4. Differences between genomic-based and pedigree-based relationships in a chicken population, as a function of quality control and pedigree links among individuals.

    Science.gov (United States)

    Wang, H; Misztal, I; Legarra, A

    2014-12-01

    This work studied differences between expected (calculated from pedigree) and realized (genomic, from markers) relationships in a real population, the influence of quality control on these differences, and their fit to current theory. Data included 4940 pure line chickens across five generations genotyped for 57,636 SNP. Pedigrees (5762 animals) were available for the five generations, pedigree starting on the first one. Three levels of quality control were used. With no quality control, mean difference between realized and expected relationships for different type of relationships was ≤ 0.04 with standard deviation ≤ 0.10. With strong quality control (call rate ≥ 0.9, parent-progeny conflicts, minor allele frequency and use of only autosomal chromosomes), these numbers reduced to ≤ 0.02 and ≤ 0.04, respectively. While the maximum difference was 1.02 with the complete data, it was only 0.18 with the latest three generations of genotypes (but including all pedigrees). Variation of expected minus realized relationships agreed with theoretical developments and suggests an effective number of loci of 70 for this population. When the pedigree is complete and as deep as the genotypes, the standard deviation of difference between the expected and realized relationships is around 0.04, all categories confounded. Standard deviation of differences larger than 0.10 suggests bad quality control, mistakes in pedigree recording or genotype labelling, or insufficient depth of pedigree. © 2014 Blackwell Verlag GmbH.

  5. Sweden - energy situation 1986

    International Nuclear Information System (INIS)

    1988-01-01

    The energy situation of Sweden is reviewed on the basis of relevant data. Data on the country's national and international energy policy are followed by an outline of trends in energy sources and electric power generation. Key figures are presented on the country's external trade and balance of payments. (UA) [de

  6. Endemic Tularemia, Sweden, 2003

    OpenAIRE

    Payne, Lara; Arneborn, Malin; Tegnell, Anders; Giesecke, Johan

    2005-01-01

    Tularemia cases have been reported in Sweden since 1931, but no cyclical patterns can be identified. In 2003, the largest outbreak of tularemia since 1967 occurred, involving 698 cases. Increased reports were received from tularemia-nonendemic areas. Causal factors for an outbreak year and associated geographic distribution are not yet understood.

  7. Sweden after the referendum

    International Nuclear Information System (INIS)

    Ragnarson, P.

    1981-01-01

    Interest in the nuclear programme has slumped in the public and political arenas since the referendum in March 1980. How Sweden is now preparing for the implementation of the limited 12-reactor programme, and the associated fuel cycle, in particular the world's first away from reactor irradiated fuel storage, is discussed. (U.K.)

  8. Pedigrees, propaganda, and paranoia: family studies in a historical context.

    Science.gov (United States)

    Lombardo, P A

    2001-01-01

    This article reviews the uses of family studies carried out in the early 20th century under the banner of eugenics, a companion discipline to early genetics. It explores how, in an attempt to analyze and quantify purportedly biologic bases of social problems, the eugenicists constructed pedigree charts of notoriously "defective" families. Investigation of individuals with suspect traits formed the basis for instruction of field workers who linked those traits to larger groups. The resulting eugenic family studies provided a "scientific" face for a popular hereditarian mythology that claimed to explain all social failure in systematic terms. The eugenicists were successful in fueling public fear about the growing "army of idiots and imbeciles" graphically depicted in their pedigree charts. Their success was the result of a finely crafted educational program--propaganda that reduced science to simplistic terms. The tendency to oversimplify concepts of genetic causation and the rush to amplify the significance of research findings through the popular media is also apparent today. What begins as publicity has the potential to be transformed into propaganda. Although many in the scientific community are understandably reluctant to revisit the abuses of the past, that community must confront the history of eugenics as a necessary antidote to the genetic hype that surrounds us.

  9. Broad scan linkage analysis in a large Tourette family pedigree

    Energy Technology Data Exchange (ETDEWEB)

    Peiffer, A.; Leppert, M. [Univ. of Utah Health Sciences Center, Salt Lake City, UT (United States); Wetering, B.J.M. van der [Univ. Hospital Rotterdam (Netherlands)

    1994-09-01

    Attempts to find a gene causing Tourette syndrome (TS) using linkage analysis have been unsuccessful even though as much as 65% of the autosomal genetic map has been excluded by the pooled results from several laboratories collaborating worldwide. One reason for this failure may be the misclassification of affection status of marry-in spouses. Specifically, we have found that six unrelated spouses in our Utah TS pedigree suffer from TS, obsessive-compulsive disorder or chronic motor tics. In light of these findings we decided to conduct a complete genomic scan from this Utah kindred with polymorphic markers in three related sibships in which there was no assortative mating. A linkage study assuming autosomal dominant inheritance was done using tetranucleotide repeat markers developed at the University of Utah. We selected markers that were less than 300 bp in size and that gave a heterozygosity of over 70% upon analysis in 4 CEPH families. Results to date with 95 markers run at an interval of 30 cM (covering 61% of the genome) show no evidence of linkage. We intend to extend the coverage to 100% of the genome. Pending completion of this scan, failure to provide evidence of linkage in our TS pedigree might then be attributed to phenotypic misclassification or erroneous assumptions regarding the genetic model of transmission.

  10. Completeness of pedigree and family cancer history for ovarian cancer patients.

    Science.gov (United States)

    Son, Yedong; Lim, Myong Cheol; Seo, Sang Soo; Kang, Sokbom; Park, Sang Yoon

    2014-10-01

    To investigate the completeness of pedigree and of number of pedigree analysis to know the acceptable familial history in Korean women with ovarian cancer. Interview was conducted in 50 ovarian cancer patients for obtaining familial history three times over the 6 weeks. The completeness of pedigree is estimated in terms of familial history of disease (cancer), health status (health living, disease and death), and onset age of disease and death. The completion of pedigree was 79.3, 85.1, and 85.6% at the 1st, 2nd, and 3rd time of interview and the time for pedigree analysis was 34.3, 10.8, and 3.1 minutes, respectively. The factors limiting pedigree analysis were as follows: out of contact with their relatives (38%), no living ancestors who know the family history (34%), dispersed family member because of the Korean War (16%), unknown cause of death (12%), reluctance to ask medical history of relatives (10%), and concealing their ovarian cancer (10%). The percentage of cancers revealed in 1st (2%) and 2nd degree (8%) relatives were increasing through surveys, especially colorectal cancer related with Lynch syndrome (4%). Analysis of pedigree at least two times is acceptable in Korean woman with ovarian cancer from the first study. The completion of pedigree is increasing, while time to take family history is decreasing during three time survey.

  11. Diet and Predatory Behavior of Lynx in Sweden

    DEFF Research Database (Denmark)

    Moshøj, Charlotte Margaret

    2002-01-01

    and hunters who fear predation on livestock and reindeer as well as a general reduction in wild game abundance, especially roe deer (Capreolus capreolus). Prey spectrum and predation of lynx was studied based on stomach analyses of lynx throughout Sweden and on data from a field study in south-central Sweden...... (reindeer and roe deer) comprised the greatest part of the diet, while a regional division indicated that while lynxes from northern regions had a narrower diet niche, they were in better condition than lynxes from south of the reindeer husbandry districts. Lynx gender and status also influenced diet...

  12. Two-level mixed modeling of longitudinal pedigree data for genetic association analysis

    DEFF Research Database (Denmark)

    Tan, Q.

    2013-01-01

    of follow-up. Approaches have been proposed to integrate kinship correlation into the mixed effect models to explicitly model the genetic relationship which have been proven as an efficient way for dealing with sample clustering in pedigree data. Although useful for adjusting relatedness in the mixed...... assess the genetic associations with the mean level and the rate of change in a phenotype both with kinship correlation integrated in the mixed effect models. We apply our method to longitudinal pedigree data to estimate the genetic effects on systolic blood pressure measured over time in large pedigrees......Genetic association analysis on complex phenotypes under a longitudinal design involving pedigrees encounters the problem of correlation within pedigrees which could affect statistical assessment of the genetic effects on both the mean level of the phenotype and its rate of change over the time...

  13. Breed-Predispositions to Cancer in Pedigree Dogs

    Science.gov (United States)

    Dobson, Jane M.

    2013-01-01

    Cancer is a common problem in dogs and although all breeds of dog and crossbred dogs may be affected, it is notable that some breeds of pedigree dogs appear to be at increased risk of certain types of cancer suggesting underlying genetic predisposition to cancer susceptibility. Although the aetiology of most cancers is likely to be multifactorial, the limited genetic diversity seen in purebred dogs facilitates genetic linkage or association studies on relatively small populations as compared to humans, and by using newly developed resources, genome-wide association studies in dog breeds are proving to be a powerful tool for unravelling complex disorders. This paper will review the literature on canine breed susceptibility to histiocytic sarcoma, osteosarcoma, haemangiosarcoma, mast cell tumours, lymphoma, melanoma, and mammary tumours including the recent advances in knowledge through molecular genetic, cytogenetic, and genome wide association studies. PMID:23738139

  14. Haplotype inference in general pedigrees with two sites

    Directory of Open Access Journals (Sweden)

    Doan Duong D

    2011-04-01

    Full Text Available Abstract Background Genetic disease studies investigate relationships between changes in chromosomes and genetic diseases. Single haplotypes provide useful information for these studies but extracting single haplotypes directly by biochemical methods is expensive. A computational method to infer haplotypes from genotype data is therefore important. We investigate the problem of computing the minimum number of recombination events for general pedigrees with two sites for all members. Results We show that this NP-hard problem can be parametrically reduced to the Bipartization by Edge Removal problem and therefore can be solved by an O(2k · n2 exact algorithm, where n is the number of members and k is the number of recombination events. Conclusions Our work can therefore be useful for genetic disease studies to track down how changes in haplotypes such as recombinations relate to genetic disease.

  15. Family genome browser: visualizing genomes with pedigree information.

    Science.gov (United States)

    Juan, Liran; Liu, Yongzhuang; Wang, Yongtian; Teng, Mingxiang; Zang, Tianyi; Wang, Yadong

    2015-07-15

    Families with inherited diseases are widely used in Mendelian/complex disease studies. Owing to the advances in high-throughput sequencing technologies, family genome sequencing becomes more and more prevalent. Visualizing family genomes can greatly facilitate human genetics studies and personalized medicine. However, due to the complex genetic relationships and high similarities among genomes of consanguineous family members, family genomes are difficult to be visualized in traditional genome visualization framework. How to visualize the family genome variants and their functions with integrated pedigree information remains a critical challenge. We developed the Family Genome Browser (FGB) to provide comprehensive analysis and visualization for family genomes. The FGB can visualize family genomes in both individual level and variant level effectively, through integrating genome data with pedigree information. Family genome analysis, including determination of parental origin of the variants, detection of de novo mutations, identification of potential recombination events and identical-by-decent segments, etc., can be performed flexibly. Diverse annotations for the family genome variants, such as dbSNP memberships, linkage disequilibriums, genes, variant effects, potential phenotypes, etc., are illustrated as well. Moreover, the FGB can automatically search de novo mutations and compound heterozygous variants for a selected individual, and guide investigators to find high-risk genes with flexible navigation options. These features enable users to investigate and understand family genomes intuitively and systematically. The FGB is available at http://mlg.hit.edu.cn/FGB/. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  16. Energy in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-11-01

    Energy in Sweden is published annually by the Swedish Energy Agency. Energy in Sweden 2004, together with its statistics supplement, Energy in Sweden: Facts and Figures 2004, is intended to provide decision-makers, journalists and the public with a single source of easily available information on conditions and developments in the energy sector. In recent years, Swedish energy and environmental policy has been increasingly concentrated on establishing or improving the long-term conditions for efficient energy markets and efficient use of energy. Restructuring of the Swedish electricity market, greater internationalisation and the effects of the energy system on the wider environment and on climate are important factors that influence the direction of energy policy and so also development of the energy markets. The line that was started by the 2002 Energy Policy Agreement, under the name of Working Together for a Reliable, Efficient and Environmentally Aware Energy Supply (Bill no. 2001/02:143), continues. The shift in taxation policy to encourage the move towards a sustainable energy system and reduced environmental impact continues, as exemplified by the introduction of the electricity certificate system on 1st May 2003. The negotiations that were started in 2003 with a view to progressive shut-down of nuclear power generation were broken off in October 2004 without having reached agreement with the nuclear power companies. As soon as the breakdown of the negotiations was announced, the Government, together with the Left Party and the Centre Party, stated that Barsebaeck 2 will be closed in 2005. Sweden's climate policy is based on the Climate Strategy Act (Bill no. 2001/02:55), which was adopted by Parliament in March 2002. It is expected that trading in emission rights, in accordance with the EU Emissions Trading Directive, will start in January 2005, with publication of national emission rights allocations on 30th September 2004. One of the more important

  17. Energy in Sweden 2004

    International Nuclear Information System (INIS)

    2004-11-01

    Energy in Sweden is published annually by the Swedish Energy Agency. Energy in Sweden 2004, together with its statistics supplement, Energy in Sweden: Facts and Figures 2004, is intended to provide decision-makers, journalists and the public with a single source of easily available information on conditions and developments in the energy sector. In recent years, Swedish energy and environmental policy has been increasingly concentrated on establishing or improving the long-term conditions for efficient energy markets and efficient use of energy. Restructuring of the Swedish electricity market, greater internationalisation and the effects of the energy system on the wider environment and on climate are important factors that influence the direction of energy policy and so also development of the energy markets. The line that was started by the 2002 Energy Policy Agreement, under the name of Working Together for a Reliable, Efficient and Environmentally Aware Energy Supply (Bill no. 2001/02:143), continues. The shift in taxation policy to encourage the move towards a sustainable energy system and reduced environmental impact continues, as exemplified by the introduction of the electricity certificate system on 1st May 2003. The negotiations that were started in 2003 with a view to progressive shut-down of nuclear power generation were broken off in October 2004 without having reached agreement with the nuclear power companies. As soon as the breakdown of the negotiations was announced, the Government, together with the Left Party and the Centre Party, stated that Barsebaeck 2 will be closed in 2005. Sweden's climate policy is based on the Climate Strategy Act (Bill no. 2001/02:55), which was adopted by Parliament in March 2002. It is expected that trading in emission rights, in accordance with the EU Emissions Trading Directive, will start in January 2005, with publication of national emission rights allocations on 30th September 2004. One of the more important tasks

  18. Decommissioning policy in Sweden

    International Nuclear Information System (INIS)

    Bergman, C.; Boge, R.; Snihs, J.O.

    1987-01-01

    In Sweden the nuclear power program is, according to a parliamentary decision, limited to twelve power producing reactors. The last reactor shall be taken out of service no later than the year 2010. As a result of the Chernobyl accident the program for taking the reactors out of service will be accelerated. This report is the first approach by the Swedish authorities to formulate a decommissioning policy. It is not the final policy document but it discusses the principal questions from the special Swedish viewpoint. (orig.)

  19. Sweden's largest Facebook study

    OpenAIRE

    Denti, Leif; Barbopoulus, Isak; Nilsson, Ida; Holmberg, Linda; Thulin, Magdalena; Wendeblad, Malin; Andén, Lisa; Davidsson, Emelie

    2012-01-01

    The emergence of the Internet has made it easier for people to socially interact than ever before. Today, the most popular channel is Facebook with over 845 million users world wide. In Sweden, the number of users amount to approximately half of the population. We had two aims with this study. First, we investigate which areas of Facebook usage that Swedish Facebook users consider more important vis-a-vis less important. We were also interested in how users convey their persona through t... m...

  20. Decommissioning policy in Sweden

    International Nuclear Information System (INIS)

    Bergman, C.; Boge, R.; Snihs, J.O.

    1987-01-01

    In Sweden the nuclear power program is, according to a parliamentary decision, limited to twelve power producing reactors. The last reactor shall be taken out of service no later than the year 2010. As a result of the Chernobyl accident the program for taking the reactors out of service will be accelerated. The first approach by the Swedish authorities to formulate a decommissioning policy is discussed. It is not the final policy document but it discusses the principal questions from the special Swedish viewpoint

  1. Bayesian pedigree inference with small numbers of single nucleotide polymorphisms via a factor-graph representation.

    Science.gov (United States)

    Anderson, Eric C; Ng, Thomas C

    2016-02-01

    We develop a computational framework for addressing pedigree inference problems using small numbers (80-400) of single nucleotide polymorphisms (SNPs). Our approach relaxes the assumptions, which are commonly made, that sampling is complete with respect to the pedigree and that there is no genotyping error. It relies on representing the inferred pedigree as a factor graph and invoking the Sum-Product algorithm to compute and store quantities that allow the joint probability of the data to be rapidly computed under a large class of rearrangements of the pedigree structure. This allows efficient MCMC sampling over the space of pedigrees, and, hence, Bayesian inference of pedigree structure. In this paper we restrict ourselves to inference of pedigrees without loops using SNPs assumed to be unlinked. We present the methodology in general for multigenerational inference, and we illustrate the method by applying it to the inference of full sibling groups in a large sample (n=1157) of Chinook salmon typed at 95 SNPs. The results show that our method provides a better point estimate and estimate of uncertainty than the currently best-available maximum-likelihood sibling reconstruction method. Extensions of this work to more complex scenarios are briefly discussed. Published by Elsevier Inc.

  2. Feminist Language Planning in Sweden

    Science.gov (United States)

    Milles, Karin

    2011-01-01

    The international literature has often described linguistic authorities as being opposed to the idea of changing language in the name of feminism. However, in Sweden, many linguistic authorities have been active agents in adopting feminist language reforms. This is probably due to Sweden's long tradition of political feminist efforts and to the…

  3. A database on electric vehicle use in Sweden. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Fridstrand, Niklas [Lund Univ. (Sweden). Dept. of Industrial Electrical Engineering and Automation

    2000-05-01

    The Department of Industrial Electrical Engineering and Automation (IEA) at the Lund Institute of Technology (LTH), has taken responsibility for developing and maintaining a database on electric and hybrid road vehicles in Sweden. The Swedish Transport and Communications Research Board, (KFB) initiated the development of this database. Information is collected from three major cities in Sweden: Malmoe, Gothenburg and Stockholm, as well as smaller cities such as Skellefteaa and Haernoesand in northern Sweden. This final report summarises the experience gained during the development and maintenance of the database from February 1996 to December 1999. Our aim was to construct a well-functioning database for the evaluation of electric and hybrid road vehicles in Sweden. The database contains detailed information on several years' use of electric vehicles (EVs) in Sweden (for example, 220 million driving records). Two data acquisition systems were used, one less and one more complex with respect to the number of quantities logged. Unfortunately, data collection was not complete, due to malfunctioning of the more complex system, and due to human factors for the less complex system.

  4. Importance of managing intangible assets in enhancing dynamic capabilities of firms: cases from Sweden and Germany

    OpenAIRE

    Schiller, Stefan; Perera, Hector

    2012-01-01

    This article reviews a social entrepreneurial initiative to set up a solar-powered incubator in Bubulo, Uganda, initiated by a group of Sweden-based entrepreneurship students. Using an Actor-Network Theoryinformed approach, it addresses the question of how the original aims of the initiative shifted as it moved from Sweden to Uganda, securing new allies and resources. In the tracing of this movement from northern Europe to central Africa, concepts from Actor-Network Theory, such as ‘translati...

  5. Acidification research in Sweden

    International Nuclear Information System (INIS)

    Staaf, H.; Bertills, U.

    1992-01-01

    A number of acid rain research programmes have been conducted in Sweden since 1978. The total cost for these programmes has amounted to about 250 million SEK, and during this period an additional 950 million SEK has been used to finance practical countermeasures, mainly lake liming. Acid deposition has caused damage to soil, lakes, groundwater, flora and fauna, buildings and materials. The role of acid rain in causing forest damage is not yet fully elucidated. However, there is strong evidence suggesting that ongoing soil acidification and nutrient imbalances associated with it pose the major threat to Swedish forests. Current ozone levels are damaging trees on the physiological level, but the effects of ozone on forest production in unknown. Liming is an efficient means of counteracting the negative effects of acidic deposition on forest soil, lakes and watercourses. 8 refs., 6 figs., 1 tab

  6. Radwaste management in Sweden

    International Nuclear Information System (INIS)

    Ahlstroem, P.E.; Ungermark, S.

    1987-01-01

    The waste management system planned for handling the radioactive residues from Sweden's 12 nuclear power units is based on the operation of all the units up to the year 2010 in accordance with Parliament's decision to abolish nuclear power by that time. The main strategy for handling spent nuclear fuel is direct disposal without reprocessing. In the design of the radwaste management system the following fundamental principles have been applied. Short-lived waste will be disposed of as soon as possible after it has been generated. Spent fuel will be intermediately stored for about 40 years before final disposal, thereby reducing heat generation in the repository. Other long-lived waste will be disposed of jointly with the final disposal of spent fuel. 3 figs., 1 tab

  7. Hierarchical linear modeling of longitudinal pedigree data for genetic association analysis

    DEFF Research Database (Denmark)

    Tan, Qihua; B Hjelmborg, Jacob V; Thomassen, Mads

    2014-01-01

    -effect models to explicitly model the genetic relationship. These have proved to be an efficient way of dealing with sample clustering in pedigree data. Although current algorithms implemented in popular statistical packages are useful for adjusting relatedness in the mixed modeling of genetic effects...... associated with blood pressure with estimated inflation factors of 0.99, suggesting that our modeling of random effects efficiently handles the genetic relatedness in pedigrees. Application to simulated data captures important variants specified in the simulation. Our results show that the method is useful......Genetic association analysis on complex phenotypes under a longitudinal design involving pedigrees encounters the problem of correlation within pedigrees, which could affect statistical assessment of the genetic effects. Approaches have been proposed to integrate kinship correlation into the mixed...

  8. In Silico Genome Mismatch Scanning to Map Breast Cancer Genes in Extended Pedigrees

    Science.gov (United States)

    2008-07-01

    University College London Annals of Human Genetics (2008) 72,279–287 279 A. Thomas et al. Methods IBD sharing in pedigrees There is considerable literature...is sufficient to maintain interest in the region. 282 Annals of Human Genetics (2008) 72,279–287 C© 2007 The Authors Journal compilation C© 2007...for observed IBS instead of IBD, and for sporadic cases reducing the number of meioses, pedigrees with meiosis count d in the 25 to 30 range are

  9. Machado-Joseph Disease in Pedigrees of Azorean descent is Linked to Chromosome 14

    OpenAIRE

    George-Hyslop, P. St; Rogaeva, E.; Huterer, J.; Tsuda, T.; Santos, J.; Haines, J. L.; Schlumpf, K.; Rogaev, E. I.; Liang, Y.; McLachlan, D. R. Crapper; Kennedy, J.; Weissenbach, J.; Billingsley, G. D.; Cox, D. W.; Lang, A. E.

    1994-01-01

    A locus for Machado-Joseph disease (MJD) has recently been mapped to a 30-cM region of chromosome 14q in five pedigrees of Japanese descent. MJD is a clinically pleomorphic neurodegenerative disease that was originally described in subjects of Azorean descent. In light of the nonallelic heterogeneity in other inherited spinocere-bellar ataxias, we were interested to determine if the MJD phenotype in Japanese and Azorean pedigrees arose from mutations at the same locus. We provide evidence tha...

  10. Detection of bias in animal model pedigree indices of heifers

    Directory of Open Access Journals (Sweden)

    M. LIDAUER

    2008-12-01

    Full Text Available The objective of the study was to test whether the pedigree indices (PI of heifers are biased, and if so, whether the magnitude of the bias varies in different groups of heifers. Therefore, two animal model evaluations with two different data sets were computed. Data with all the records from the national evaluation in December 1994 was used to obtain estimated breeding values (EBV for 305-days' milk yield and protein yield. In the second evaluation, the PIs were estimated for cows calving the first time in 1993 by excluding all their production records from the data. Three different statistics, a simple t-test, the linear regression of EBV on PI, and the polynomial regression of the difference in the predictions (EBV-PI on PI, were computed for three groups of first parity Ayrshire cows: daughters of proven sires, daughters of young sires, and daughters of bull dam candidates. A practically relevant bias was found only in the PIs for the daughters of young sires. On average their PIs were biased upwards by 0.20 standard deviations (78.8 kg for the milk yield and by 0.21 standard deviations (2.2 kg for the protein yield. The polynomial regression analysis showed that the magnitude of the bias in the PIs changed somewhat with the size of the PIs.;

  11. Two pedigrees of familial advanced sleep phase syndrome in Japan.

    Science.gov (United States)

    Satoh, Kohtoku; Mishima, Kazuo; Inoue, Yuichi; Ebisawa, Takashi; Shimizu, Tetsuo

    2003-06-15

    To determine whether a known missense mutation (bp2106 A/G) in hPer2 (a human homolog of the Drosophila period gene) for familial advanced sleep phase syndrome in a Caucasian family is involved in Japanese familial advanced sleep phase syndrome pedigrees. We identified 2 new Japanese families with advanced sleep phase syndrome, and a systematic survey was carried out in 28 relatives of theses 2 families. A total of 9 affected subjects were identified. The affected members showed significantly strong morningness tendencies compared with the unaffected members in various circadian parameters including the Horne-Ostberg Morningness-Eveningness Questionnaire score (77.3 +/- 4.8 vs 57.5 +/- 7.6, p sleep-onset time (20:45 +/- 75 min vs 23:16 +/- 64 min, p DNA samples were obtained from 7 affected and 7 unaffected subjects. None of the tested subjects possessed the missense mutation (bp2106 A/G) in hPer2. Furthermore, there is no significant linkage between affected subjects with hPer2 region by 2-point mapping and by direct sequencing of 23 exons of hPer2. These findings support the notion of genetic heterogeneity of familial advanced sleep phase syndrome cases in humans. The search for more familial advanced sleep phase syndrome cases and for loci other than hPer2 are necessary to further examine the roles of circadian-related genes in genetically determined human circadian rhythm disorders.

  12. Estimating Heritability from Nuclear Family and Pedigree Data.

    Science.gov (United States)

    Bochud, Murielle

    2017-01-01

    Heritability is a measure of familial resemblance. Estimating the heritability of a trait could be one of the first steps in the gene mapping process. This chapter describes how to estimate heritability for quantitative traits from nuclear and pedigree data using the ASSOC program in the Statistical Analysis in Genetic Epidemiology (S.A.G.E.) software package. Estimating heritability rests on the assumption that the total phenotypic variance of a quantitative trait can be partitioned into independent genetic and environmental components. In turn, the genetic variance can be divided into an additive (polygenic) genetic variance, a dominance variance (nonlinear interaction effects between alleles at the same locus) and an epistatic variance (interaction effects between alleles at different loci). The last two are often assumed to be zero. The additive genetic variance represents the average effects of individual alleles on the phenotype and reflects transmissible resemblance between relatives. Heritability in the narrow sense (h 2 ) refers to the ratio of the additive genetic variance to the total phenotypic variance. Heritability is a dimensionless population-specific parameter. ASSOC estimates association parameters (regression coefficients) and variance components from family data. ASSOC uses a linear regression model in which the total residual variance is partitioned, after regressing on covariates, into the sum of random components such as an additive polygenic component, a random sibship component, random nuclear family components, a random marital component, and an individual-specific random component. Assortative mating, nonrandom ascertainment of families, and failure to account for key confounding factors may bias heritability estimates.

  13. A Large PROP1 Gene Deletion in a Turkish Pedigree

    Directory of Open Access Journals (Sweden)

    Suheyla Gorar

    2018-01-01

    Full Text Available Pituitary-specific paired-like homeodomain transcription factor, PROP1, is associated with multiple pituitary hormone deficiency. Alteration of the gene encoding the PROP1 may affect somatotropes, thyrotropes, and lactotropes, as well as gonadotropes and corticotropes. We performed genetic analysis of PROP1 gene in a Turkish pedigree with three siblings who presented with short stature. Parents were first degree cousins. Index case, a boy, had somatotrope, gonadotrope, thyrotrope, and corticotrope deficiency. However, two elder sisters had somatotroph, gonadotroph, and thyrotroph deficiency and no corticotroph deficiency. On pituitary magnetic resonance, partial empty sella was detected with normal bright spot in all siblings. In genetic analysis, we found a gross deletion involving PROP1 coding region. In conclusion, we report three Turkish siblings with a gross deletion in PROP1 gene. Interestingly, although little boy with combined pituitary hormone deficiency has adrenocorticotropic hormone (ACTH deficiency, his elder sisters with the same gross PROP1 deletion have no ACTH deficiency. This finding is in line with the fact that patients with PROP1 mutations may have different phenotype/genotype correlation.

  14. Ethical issues in bipolar disorders pedigree research: privacy concerns, informed consent, and grounds for waiver.

    Science.gov (United States)

    Parker, Lisa S

    2002-02-01

    Focusing on bipolar disorders research, this article considers ethical issues of informed consent and privacy arising in genetic pedigree research at two stages: the construction of tentative pedigrees to determine family eligibility for study and, subsequently, the enrollment of subjects in and conduct of the family study. Increasing concern to protect the privacy of family members of primary subjects or probands, following ethical controversy over a survey study at Virginia Commonwealth University, has led some researchers and Institutional Review Boards (IRBs) to apply informed consent requirements to those represented on a tentative pedigree at the initial stage of research. This article analyzes the possible benefits, risks, and burdens to prospective subjects of seeking prospective consent for pedigree construction at this initial stage. It argues that the likely risk-benefit ratio favors granting a waiver of consent requirements for this stage of pedigree research and presents grounds for IRBs to grant such a waiver. The article closes by considering particular ethical concerns that should be addressed in the informed consent discussion when enrolling subjects in pedigree studies of bipolar disorder, including concerns about subjects' competence to consent, management of interim and incidental findings, and issues particular to psychiatric research.

  15. The English and northern (Sweden and Norway) systems regarding the questions posed by the white book; Les systemes anglais et nordiques (Suede et Norvege) au regard des questions posees dans le livre blanc

    Energy Technology Data Exchange (ETDEWEB)

    Secretariat d' Etat a l' Industrie [ed.] [Secretariat d' Etat a l' Industrie, Ministere de l' Economie, des Finances et de l' Industrie, Paris (France)

    1999-06-15

    annually a report on market progress. In liberalized systems still two more features are worth to mention, the appearance of actors unknown in centralized systems (as the suppliers, for instance) and the high 'volatility' of the electricity prices that presses both manufacturers and customers to protect themselves against the market's risks. The second part of the report is devoted to the questions raised in the White Book, namely, service's quality, economic efficiency, service continuity, etc. In conclusion, the French conception of Public Service has not an exact analogue but most of its objectives are assigned actually to the Network Authority, the main task of which is promotion of economic efficiency. The networks either privatized, as in United Kingdom, or still public, as in Norway or Swede, are closely controlled by the Network Authority. This is done via price structure establishment and by imposing an upper level on the revenue of the network operators. In UK the action of the Network Authority was highly instrumental in growth of productivity in the monopolistic sectors of electric industry, i.e., transport and distribution. Norway and Swede are in retard from this point of view. The main beneficiaries of the market liberalization were the industries while the profit of domestic customers is still incipient. In the northern countries in spite of early access to competition the profit was so far low. In its second part the document APIS of the Council for Industrial Policy poses questions and presents ways of approach in UK and northern countries relating to: - The directive and its range; - Reinforcing the Public Service; - Revamping the Electric System to support growth; Preserving the networks for overall profit; - Defining of Public Establishment EDF within the new organization; - Developing an efficient network. Ways of approach in UK and northern countries regulation are presented.

  16. Neutron Powder Diffraction in Sweden

    International Nuclear Information System (INIS)

    Tellgren, R.

    1986-01-01

    Neutron powder diffraction in Sweden has developed around the research reactor R2 in Studsvik. The article describes this facility and presents a historical review of research results obtained. It also gives some ideas of plans for future development

  17. Conversion program in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Jonsson, E.B. [Studsvik Nuclear AB, Nykoeping (Sweden)

    1997-08-01

    The conversion of the Swedish 50 MW R2 reactor from HEU to LEU fuel has been successfully accomplished over a 16 cycles long process. The conversion started in January 1991 with the introduction of 6 LEU assemblies in the 8*8 core. The first all LEU core was loaded in March 1993 and physics measurements were performed for the final licensing reports. A total of 142 LEU fuel assemblies have been irradiated up until September 1994 without any fuel incident. The operating licence for the R2 reactor was renewed in mid 1994 taking into account new fuel type. The Swedish Nuclear Inspectorate (SKI) pointed out one crucial problem with the LEU operation, that the back end of the LEU fuel cycle has not yet been solved. For the HEU fuel Sweden had the reprocessing alternative. The country is now relying heavily on the success of the USDOEs Off Site Fuels Policy to take back the spent fuel from the research reactors. They have in the meantime increased their intermediate storage facilities. There is, however, a limit both in time and space for storage of MTR-type of assemblies in water. The penalty of the lower thermal neutron flux in LEU cores has been reduced by improvements of the new irradiation rigs and by fine tuning the core calculations. The Studsvik code package, CASMO-SIMULATE, widely used for ICFM in LWRs has been modified to suit the compact MTR type of core.

  18. Uranium production in Sweden

    International Nuclear Information System (INIS)

    Bergh, S.

    1994-01-01

    The history of uranium production in Sweden is reviewed in the article. The World War II led to an exploitation of the Swedish alum shale on a large scale. In the last phase of the war it also became obvious that the shale might be used for energy production of quite another kind than oil. In 1947 AB Atom energy was founded, an enterprise with one of its purposes to extract uranium for peaceful use. A plant with a yearly capacity of 120 tons of uranium was erected at Ranstad and ready for production by 1965. From the start in Ranstad and for many years to come there was hardly any interest in an immediate large uranium production. It was decided to use the plant for studies on its more effective exploitation in case of an expansion in the future, bearing in mind the reactor programme. In the course of time economical reasons began to speak against the project. The shale seemed to have a future neither as oil nor as uranium resource. The complete termination of the work on uranium production from shale occurred in 1989

  19. Dieselization in Sweden

    International Nuclear Information System (INIS)

    Kågeson, Per

    2013-01-01

    In Sweden the market share of diesel cars grew from below 10 per cent in 2005 to 62 per cent in 2011 despite a closing gap between pump prices on diesel oil and gasoline, and diesel cars being less favored than ethanol and biogas cars in terms of tax cuts and other subsidies offered to “environment cars”. The most important factor behind the dieselization was probably the market entrance of a number of low-consuming models. Towards the end of the period a growing number of diesel models were able to meet the 120 g CO 2 threshold applicable to “environment cars” that cannot use ethanol or biogas. This helped such models increase their share of the diesel car market from zero to 41 per cent. Dieselization appears to have had only a minor effect on annual distances driven. The higher average annual mileage of diesel cars is probably to a large extent a result of a self-selection bias. However, the Swedish diesel car fleet is young, and the direct rebound effect stemming from a lower variable driving cost may show up more clearly as the fleet gets older based on the assumption that second owners are more fuel price sensitive than first owners. - Highlights: ► This paper tries to explain the fast dieselization of the new Swedish car fleet. ► It identifies changes in supply and the impact of tax benefits. ► Finally it studies the impact on the annual average mileage

  20. Nuclear power in Sweden

    International Nuclear Information System (INIS)

    Wikdahl, C.E.

    1999-01-01

    Sweden uses 16,000 kWh of electricity per person, by far the highest consumption in EU. The reason is a well-developed electricity intensive industry and a cold climate with high share of electric heating. The annual power consumption has for several years been about 140 TWh and a normal year almost 50 per cent is produced by hydro and 50 percent by nuclear. A new legislation, giving the Government the right to ordering the closure nuclear power plants of political reasons without any reference to safety, has been accepted by the Parliament. The new act, in force since January 1, 1998, is a specially tailored expropriation act. Certain rules for the economical compensation to the owner of a plant to be closed are defined in the new act. The common view in the Swedish industry is that the energy conservation methods proposed by the Government are unrealistic. During the first period of about five years the import from coal fired plants in Denmark and Germany is the only realistic alternative. Later natural gas combi units and new bioenergy plants for co-production of heat and power (CHP) might be available. (orig.) [de

  1. Identification of kin structure among Guam rail founders: a comparison of pedigrees and DNA profiles

    Science.gov (United States)

    Haig, Susan M.; Ballou, J.D.; Casna, N.J.

    1994-01-01

    Kin structure among founders can have a significant effect on subsequent population structure. Here we use the correlation between DNA profile similarity and relatedness calculated from pedigrees to test hypotheses regarding kin structure among founders to the captive Guam rail (Rallus owstoni) population. Five different pedigrees were generated under the following hypotheses: (i) founders are unrelated; (ii) founders are unrelated except for same-nest chicks; (iii) founders from the same major site are siblings; (iv) founders from the same local site are siblings; and (v) founders are related as defined by a UPGMA cluster analysis of DNA similarity data. Relatedness values from pedigrees 1, 2 and 5 had the highest correlation with DNA similarity but the correlation between relatedness and similarity were not significantly different among pedigrees. Pedigree 5 resulted in the highest correlation overall when using only relatedness values that changed as a result of different founder hypotheses. Thus, founders were assigned relatedness based on pedigree 5 because it had the highest correlations with DNA similarity, was the most conservative approach, and incorporated all field data. The analyses indicated that estimating relatedness using DNA profiles remains problematic, therefore we compared mean kinship, a measure of genetic importance, with mean DNA profile similarity to determine if genetic importance among individuals could be determined via use of DNA profiles alone. The significant correlation suggests this method may provide more information about population structure than was previously thought. Thus, DNA profiles can provide a reasonable explanation for founder relatedness and mean DNA profile similarity may be helpful in determining relative genetic importance of individuals when detailed pedigrees are absent.

  2. Biology and outbreaks of Microdiprion pallipes (Hymenoptera; Diprionidae) in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Olofsson, E. (Swedish Univ. of Agricultural Sciences, Uppsala (Sweden). Dept. of Entomology)

    1994-01-01

    During outbreaks, Microdiprion pallipes (Fall.) is the most destructive of the pine sawflies in Sweden. Its distribution includes most provinces, but damaging outbreaks have until recently occurred only in two inland areas in northern Sweden. These areas are characterised by high elevation, a harsh climate, and slow tree growth. The four recorded outbreak periods showed a 10 year periodicity. Outside these areas, a lesser outbreak occurred in 1988 to 1990, on the east coast (province of Uppland). Outbreak patterns, life history variation, and mortality factors were studied. Factors that may explain the distribution of outbreaks and the population patterns were identified.Experimental and observational evidence on the potential of various factors to influence fecundity, dispersal, and survival was evaluated. In the outbreak areas, there were few major population factors. Parasitism by Rhorus substitutor (Thunb.) was the largest cause of larval mortality and the only important density-dependent mortality factor. The different diapause strategies of M. pallipes and R. substitutor may contribute to stabilize this system. Different flight periods of the host and the parasitoid may explain a possible correlation between weather and outbreaks. Elsewhere in Sweden, where low population densities prevail, there may be similarities in population processes between M. pallipes and the other widely distributed diprionids with solitary larvae, which never have attained outbreak densities in Sweden. Interactions with other diprionids through shared natural enemies may be an important population process and may influence the distribution of outbreaks. 37 refs, 4 figs, 11 tabs

  3. Pedigrees or markers: Which are better in estimating relatedness and inbreeding coefficient?

    Science.gov (United States)

    Wang, Jinliang

    2016-02-01

    Individual inbreeding coefficient (F) and pairwise relatedness (r) are fundamental parameters in population genetics and have important applications in diverse fields such as human medicine, forensics, plant and animal breeding, conservation and evolutionary biology. Traditionally, both parameters are calculated from pedigrees, but are now increasingly estimated from genetic marker data. Conceptually, a pedigree gives the expected F and r values, FP and rP, with the expectations being taken (hypothetically) over an infinite number of individuals with the same pedigree. In contrast, markers give the realised (actual) F and r values at the particular marker loci of the particular individuals, FM and rM. Both pedigree (FP, rP) and marker (FM, rM) estimates can be used as inferences of genomic inbreeding coefficients FG and genomic relatedness rG, which are the underlying quantities relevant to most applications (such as estimating inbreeding depression and heritability) of F and r. In the pre-genomic era, it was widely accepted that pedigrees are much better than markers in delineating FG and rG, and markers should better be used to validate, amend and construct pedigrees rather than to replace them. Is this still true in the genomic era when genome-wide dense SNPs are available? In this simulation study, I showed that genomic markers can yield much better estimates of FG and rG than pedigrees when they are numerous (say, 10(4) SNPs) under realistic situations (e.g. genome and population sizes). Pedigree estimates are especially poor for species with a small genome, where FG and rG are determined to a large extent by Mendelian segregations and may thus deviate substantially from their expectations (FP and rP). Simulations also confirmed that FM, when estimated from many SNPs, can be much more powerful than FP for detecting inbreeding depression in viability. However, I argue that pedigrees cannot be replaced completely by genomic SNPs, because the former allows for

  4. Next Generation Sequencing Plus (NGS+) with Y-chromosomal Markers for Forensic Pedigree Searches.

    Science.gov (United States)

    Qian, Xiaoqin; Hou, Jiayi; Wang, Zheng; Ye, Yi; Lang, Min; Gao, Tianzhen; Liu, Jing; Hou, Yiping

    2017-09-12

    There is high demand for forensic pedigree searches with Y-chromosome short tandem repeat (Y-STR) profiling in large-scale crime investigations. However, when two Y-STR haplotypes have a few mismatched loci, it is difficult to determine if they are from the same male lineage because of the high mutation rate of Y-STRs. Here we design a new strategy to handle cases in which none of pedigree samples shares identical Y-STR haplotype. We combine next generation sequencing (NGS), capillary electrophoresis and pyrosequencing under the term 'NGS+' for typing Y-STRs and Y-chromosomal single nucleotide polymorphisms (Y-SNPs). The high-resolution Y-SNP haplogroup and Y-STR haplotype can be obtained with NGS+. We further developed a new data-driven decision rule, FSindex, for estimating the likelihood for each retrieved pedigree. Our approach enables positive identification of pedigree from mismatched Y-STR haplotypes. It is envisaged that NGS+ will revolutionize forensic pedigree searches, especially when the person of interest was not recorded in forensic DNA database.

  5. [Essentials of pharmacophylogeny: knowledge pedigree, epistemology and paradigm shift].

    Science.gov (United States)

    Hao, Da-cheng; Xiao, Pei-gen; Liu, Li-wei; Peng, Yong; He, Chun-nian

    2015-09-01

    Chinese materia medica resource (CMM resource) is the foundation of the development of traditional Chinese medicine. In the study of sustainable utilization of CMM resource, adopting innovative theory and method to find new CMM resource is one of hotspots and always highlighted. Pharmacophylogeny interrogates the phylogenetic relationship of medicinal organisms (especially medicinal plants), as well as the intrinsic correlation of morphological taxonomy, molecular phylogeny, chemical constituents, and therapeutic efficacy (ethnopharmacology and pharmacological activity). This new discipline may have the power to change the way we utilize medicinal plant resources and develop plant-based drugs. Phylogenomics is the crossing of evolutionary biology and genomics, in which genome data are utilized for evolutionary reconstructions. Phylogenomics can be integrated into the flow chart of drug discovery and development, and extends the field of pharmacophylogeny at the omic level, thus the concept of pharmacophylogenomics could be redefined in the context of plant pharmaceutical resources. This contribution gives a brief discourse of knowledge pedigree of pharmacophylogeny, epistemology and paradigm shift, highlighting the theoretical and practical values of pharmacophylogenomics. Many medicinally important tribes and genera, such as Clematis, Pulsatilla, Anemone, Cimicifugeae, Nigella, Delphinieae, Adonideae, Aquilegia, Thalictrum, and Coptis, belong to Ranunculaceae family. Compared to other plant families, Ranunculaceae has the most species that are recorded in China Pharmacopoeia (CP) 2010. However, many Ranunculaceae species, e. g., those that are closely related to CP species, as well as those endemic to China, have not been investigated in depth, and their phylogenetic relationship and potential in medicinal use remain elusive. As such, it is proposed to select Ranunculaceae to exemplify the utility of pharmacophylogenomics and to elaborate the new concept

  6. Women and energy in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Rising, Agneta [Vattenfall - Swedish State Power Board (Sweden)

    1989-07-01

    Sweden is currently facing a new situation In energy politics. Nuclear power is to be phased out nd replaced by new energy sources and by more effective use of electricity. This will be a great change for the whole society as nuclear power today is giving half of electricity. And Sweden is a high-consumption- country, in fact looking at the top list of electricity consumption per capita in the world, you will find Sweden on the fourth plate. In general- women know less than men about the relation between energy, technology, environment and economy. This knowledge is required If women re to Influence the choice of future energy supplies of Sweden. It is with this background the project 'Women and Energy' has been started. Important decisions are to be made within their fairly immediate future with major consequences for Sweden's coming development. These decisions have until now often been made by men, but now it Is the hope of Vattenfall that women will be able to influence these decisions. So that all of 'nuclear people' may share responsibility the path that has been chosen.

  7. Women and energy in Sweden

    International Nuclear Information System (INIS)

    Rising, Agneta

    1989-01-01

    Sweden is currently facing a new situation In energy politics. Nuclear power is to be phased out nd replaced by new energy sources and by more effective use of electricity. This will be a great change for the whole society as nuclear power today is giving half of electricity. And Sweden is a high-consumption- country, in fact looking at the top list of electricity consumption per capita in the world, you will find Sweden on the fourth plate. In general- women know less than men about the relation between energy, technology, environment and economy. This knowledge is required If women re to Influence the choice of future energy supplies of Sweden. It is with this background the project 'Women and Energy' has been started. Important decisions are to be made within their fairly immediate future with major consequences for Sweden's coming development. These decisions have until now often been made by men, but now it Is the hope of Vattenfall that women will be able to influence these decisions. So that all of 'nuclear people' may share responsibility the path that has been chosen

  8. Epidemiology and Ecology of Tularemia in Sweden, 1984–2012

    Science.gov (United States)

    Desvars, Amélie; Furberg, Maria; Hjertqvist, Marika; Vidman, Linda; Sjöstedt, Anders; Rydén, Patrik

    2015-01-01

    The zoonotic disease tularemia is endemic in large areas of the Northern Hemisphere, but research is lacking on patterns of spatial distribution and connections with ecologic factors. To describe the spatial epidemiology of and identify ecologic risk factors for tularemia incidence in Sweden, we analyzed surveillance data collected over 29 years (1984–2012). A total of 4,830 cases were notified, of which 3,524 met all study inclusion criteria. From the first to the second half of the study period, mean incidence increased 10-fold, from 0.26/100,000 persons during 1984–1998 to 2.47/100,000 persons during 1999–2012 (ptularemia was higher than expected in the boreal and alpine ecologic regions (ptularemia in Sweden and illustrate that incidence is higher in locations near lakes and rivers. PMID:25529978

  9. Policies promoting Biofuels in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Holmgren, Kristina [IVL Swedish Environmental Research Inst., Goeteborg (Sweden); Chalmers Univ. of Technology, Div. of Heat and Power Technology., Goeteborg (Sweden)

    2012-07-01

    This report was written as part of a course in Environmental Economics and Policy Instruments at the University of Gothenburg. It aims at summarizing the policy instruments introduced to directly affect the production and use of biofuels in Sweden. Since Sweden is part of the EU also EU policies were included. There are additional policy instruments which affect the production and utilization of biofuels in a more indirect way that are not presented here. The economic analysis in this paper is limited and could be developed from the information presented in order to draw further conclusions on necessary changes in order to reach set targets.

  10. Protecting the privacy of family members in survey and pedigree research.

    Science.gov (United States)

    Botkin, J

    2001-01-10

    The recent controversy at Virginia Commonwealth University involving research ethics raises important and complex issues in survey and pedigree research. The primary questions are whether family members of survey respondents themselves become subjects of the project and if they are subjects whether informed consent must be obtained for investigators to retain private information on these individuals. This article provides an analysis of the ethical issues and regulatory standards involved in this debate for consideration by investigators and institutional review boards. The analysis suggests that strong protections for the rights and welfare of subjects and their family members can be incorporated into survey and pedigree research protocols without hindering projects with extensive consent requirements.

  11. Child Care in Sweden. Fact Sheets on Sweden.

    Science.gov (United States)

    Swedish Inst., Stockholm.

    This fact sheet outlines Sweden's policies of government-supported child care and parental insurance provisions. Swedish families receive: (1) free maternity and child health care; (2) child allowances for each child of 9,000 krona per year through age 16; (3) up to 450 days of paid parental leave for the birth of a child, with 360 days paid at 90…

  12. The Pursuit of Metals and the Ideology of Improvement in Early Modern Sápmi, Sweden

    DEFF Research Database (Denmark)

    Naum, Magdalena Ewa

    2017-01-01

    The article examines the ideology of improvement in the context of seventeenth- and eighteenth-century mining in northern Sweden in the province of Sápmi. It discusses how the rhetoric of improvement and “civilizing” projects were intertwined with the mining enterprises; how they informed...

  13. English Language Teaching Profile: Sweden.

    Science.gov (United States)

    British Council, London (England). English-Teaching Information Centre.

    This profile in outline form of the English language teaching situation in Sweden discusses the role of English within Swedish society and within the Swedish educational system. The status of English as the principal foreign language since 1945 for use in business, the media and tourism is pointed out. The system of English instruction in the…

  14. Foreign Language Learning in Sweden.

    Science.gov (United States)

    Orpet, Brian R.

    1984-01-01

    Describes a visit made to Sweden to ascertain why Swedish citizens speak such excellent English. Motivation was a key factor. Describes observations of the methods of teaching English as a second language in Swedish schools. Makes recommendations for foreign language teaching in Great Britain based on these observations. (SED)

  15. The energy transition in Sweden

    International Nuclear Information System (INIS)

    Cruciani, Michel

    2016-06-01

    Sweden has the distinction of having started several major changes to its energy supply at an early stage. The country has no fossil reserves, and so was importing increasing volumes of oil products in the years following World War II. Yet it rapidly perceived the geopolitical risks generated by such oil dependency, and so developed its nuclear capacity, enabling it to reduce quickly the role of oil in its economy after the shocks of the 1970's. Sweden has also managed to exploit its natural resources. Until the 2000's, hydropower was able to enter the market without public assistance. By contrast, wood could not have gained its current market share without a policy combining public aid for investment and penalties for competing energies. The severe economic crisis which hit the country between 1991 and 1993 led such penalties being converted into taxes, notably a tax on CO_2 emissions that came into force in 1991. This helped Sweden reconstruct its tax system, to finance its social model. The challenge highlighted the country's ability to generate consensus policy guidelines. One of these guidelines was to react immediately after initial warnings about climate change. Sweden first strengthened its energy efficiency policy, structuring field actions through a national agency backed up by partner organizations in local communities to help consumers - individuals or industries - technically and economically. Sweden then adopted an unusual instrument to promote renewable electricity, namely its system of green certificates. Implemented in 2003, this system has spurred the development of the cheapest sources of renewable energy, two-thirds coming from onshore wind and one third from biomass. The cost of this support still remains remarkably moderate today. At the end of 2014, Sweden thus only used fossil fuels to provide 30% of its primary energy supplies, while renewables accounted for 52% of final energy consumption. Energy consumption per capita remains high, but

  16. High mitochondrial mutation rates estimated from deep-rooting Costa Rican pedigrees

    Science.gov (United States)

    Madrigal, Lorena; Melendez-Obando, Mauricio; Villegas-Palma, Ramon; Barrantes, Ramiro; Raventos, Henrieta; Pereira, Reynaldo; Luiselli, Donata; Pettener, Davide; Barbujani, Guido

    2012-01-01

    Estimates of mutation rates for the noncoding hypervariable Region I (HVR-I) of mitochondrial DNA (mtDNA) vary widely, depending on whether they are inferred from phylogenies (assuming that molecular evolution is clock-like) or directly from pedigrees. All pedigree-based studies so far were conducted on populations of European origin. In this paper we analyzed 19 deep-rooting pedigrees in a population of mixed origin in Costa Rica. We calculated two estimates of the HVR-I mutation rate, one considering all apparent mutations, and one disregarding changes at sites known to be mutational hot spots and eliminating genealogy branches which might be suspected to include errors, or unrecognized adoptions along the female lines. At the end of this procedure, we still observed a mutation rate equal to 1.24 × 10−6, per site per year, i.e., at least three-fold as high as estimates derived from phylogenies. Our results confirm that mutation rates observed in pedigrees are much higher than estimated assuming a neutral model of long-term HVRI evolution. We argue that, until the cause of these discrepancies will be fully understood, both lower estimates (i.e., those derived from phylogenetic comparisons) and higher, direct estimates such as those obtained in this study, should be considered when modeling evolutionary and demographic processes. PMID:22460349

  17. [Molecular genetic analysis for a pedigree with severe hereditary coagulation factor VII deficiency].

    Science.gov (United States)

    Ding, Qiu-lan; Wang, Hong-li; Wang, Xue-feng; Wang, Ming-shan; Fu, Qi-hua; Wu, Wen-man; Hu, Yi-qun; Wang, Zhen-yi

    2003-10-01

    To identify the genetic mutations of a severe inherited coagulation factor VII (FVII) deficiency pedigree. The diagnosis was validated by coagulant and haemostatic parameters. FVII gene mutations were screened in the propositus and his family members by DNA direct sequencing and confirmed by digestions of the restriction enzymes of the PCR production. Two heterozygous missense mutations were found in the propositus of the pedigree: a G to T transversion at position 9482 in exon 6 and a C to T mutation at position 11348 in exon 8 resulting in the amino acid substitution of Arg152 with Leu and Arg304 with Trp, respectively. A heterozygous single nucleotide deletion (C) at position 11487-11489(CCC) within exon 8 was identified, which predicted the frameshift mutation at position His351 followed by the changes of six corresponding amino acids and appearance of a premature protein caused by stop codon. The heterozygous mutations identified in the proband were derived from his father (Arg152 to Leu) and his mother (Arg304 to Trp mutation) and a heterozygous deletion (C) at position 11487-9(CCC). By tracing the other pedigree members, it was found that his grandmother had a heterozygous mutation of Arg304Trp and a heterozygous polymorphism of Arg353Gln and his grandfather had a heterozygous Arg152Leu mutation. Three heterozygous mutations were found in a pedigree with hereditary coagulation factor VII deficiency. Arg152Leu and deletion C at position 11487-9(CCC) were novel mutations.

  18. Inheritance of RFLP loci in a loblolly pine three-generation pedigree

    Science.gov (United States)

    M.D. Devey; K.D. Jermstad; C.G. Tauer; D.B. Neale

    1991-01-01

    A high-density restriction fragment length polymorphism (RFLP) linkage map is being constructed for loblolly pine (Pinus taeda L.). Loblolly pine cDNA and genomic DNA clones were used as probes in hybridizations to genomic DNAs prepared from grandparents, parents, and progeny of a three-generation outbred pedigree. Approximately 200 probes were...

  19. PRIMAL: Fast and accurate pedigree-based imputation from sequence data in a founder population.

    Directory of Open Access Journals (Sweden)

    Oren E Livne

    2015-03-01

    Full Text Available Founder populations and large pedigrees offer many well-known advantages for genetic mapping studies, including cost-efficient study designs. Here, we describe PRIMAL (PedigRee IMputation ALgorithm, a fast and accurate pedigree-based phasing and imputation algorithm for founder populations. PRIMAL incorporates both existing and original ideas, such as a novel indexing strategy of Identity-By-Descent (IBD segments based on clique graphs. We were able to impute the genomes of 1,317 South Dakota Hutterites, who had genome-wide genotypes for ~300,000 common single nucleotide variants (SNVs, from 98 whole genome sequences. Using a combination of pedigree-based and LD-based imputation, we were able to assign 87% of genotypes with >99% accuracy over the full range of allele frequencies. Using the IBD cliques we were also able to infer the parental origin of 83% of alleles, and genotypes of deceased recent ancestors for whom no genotype information was available. This imputed data set will enable us to better study the relative contribution of rare and common variants on human phenotypes, as well as parental origin effect of disease risk alleles in >1,000 individuals at minimal cost.

  20. Distribution of volatile composition in 'marion' ( rubus species hyb) blackberry pedigree.

    Science.gov (United States)

    Du, Xiaofen; Finn, Chad; Qian, Michael C

    2010-02-10

    The distribution of volatile constituents in ancestral genotypes of 'Marion' blackberry's pedigree was investigated over two growing seasons. Each genotype in the pedigree had a specific volatile composition. Red raspberry was dominated by norisoprenoids, lactones, and acids. 'Logan' and 'Olallie' also had a norisoprenoid dominance but at much lower concentrations. The concentration of norisoprenoids in other blackberry genotypes was significantly lower. Terpenes and furanones were predominant in wild 'Himalaya' blackberry, whereas terpenes were the major volatiles in 'Santiam'. 'Marion', a selection from 'Chehalem' and 'Olallie', contained almost all of the volatile compounds in its pedigree at moderate amount. The chiral isomeric ratios of 11 pairs of compounds were also studied. Strong chiral isomeric preference was observed for most of the chiral compounds, and each cultivar had its unique chiral isomeric distribution. An inherent pattern was observed for some volatile compounds in the 'Marion' pedigree. Raspberry and 'Logan' had a very high concentration of beta-ionone, but was reduced by half in 'Olallie' and by another half in 'Marion' as the crossing proceeded. A high content of linalool in 'Olallie' and a low content in 'Chehalem' resulted in a moderate content of linalool in their progeny 'Marion'. However, the concentration of furaneol in 'Marion' was higher than in its parents. A high content of (S)-linalool in 'Olallie' and a racemic content of (S)-,(R)-linalool in 'Chehalem' resulted in a preference for the (S)-form in 'Marion'.

  1. Rooster Semen Cryopreservation: Effect of Pedigree Line and Male Age on Post-Thaw Sperm Function

    Science.gov (United States)

    The fertility rates of cryopreserved poultry semen are highly variable and not reliable for use in preservation of commercial genetic stocks. Our objective was to evaluate the cryosurvival of semen from 8 pedigreed layer lines at the onset and end of production. Semen from 160 roosters (20/line) was...

  2. Identification of quantitative trait loci influencing wood specific gravity in an outbred pedigree of loblolly pine

    Science.gov (United States)

    A. Groover; M. Devey; T. Fiddler; J. Lee; R. Megraw; T. Mitchel-Olds; B. Sherman; S. Vujcic; C. Williams; D. Neale

    1994-01-01

    We report the identification of quantitative trait loci (QTL) influencing wood specific gravity (WSG) in an outbred pedigree of loblolly pine (Pinus taeda L.) . QTL mapping in an outcrossing species is complicated by the presence of multiple alleles (>2) at QTL and marker loci. Multiple alleles at QTL allow the examination of interaction among...

  3. A complete genome screen for genes predisposing to severe bipolar disorder in two Costa Rican pedigrees

    NARCIS (Netherlands)

    McInnes, LA; Escamilla, MA; Service, SK; Reus, [No Value; Leon, P; Silva, S; Rojas, E; Spesny, M; Baharloo, S; Blankenship, K; Peterson, A; Tyler, D; Shimayoshi, N; Tobey, C; Batki, S; Vinogradov, S; Meza, L; Gallegos, A; Fournier, E; Smith, LB; Barondes, SH; Sandkuijl, LA; Freimer, NB

    1996-01-01

    Bipolar mood disorder (BP) is a debilitating syndrome characterized by episodes of mania and depression. We designed a multistage study to detect all major loci predisposing to severe BP (termed BP-I) in two pedigrees drawn from the Central Valley of Costa Rica, where the population is largely

  4. Consequences for diversity when prioritizing animals for conservation with pedigree or genomic information

    NARCIS (Netherlands)

    Engelsma, K.A.; Veerkamp, R.F.; Calus, M.P.L.; Windig, J.J.

    2011-01-01

    Up to now, prioritization of animals for conservation has been mainly based on pedigree information; however, genomic information may improve prioritization. In this study, we used two Holstein populations to investigate the consequences for genetic diversity when animals are prioritized with

  5. Multilocus lod scores in large pedigrees: combination of exact and approximate calculations.

    Science.gov (United States)

    Tong, Liping; Thompson, Elizabeth

    2008-01-01

    To detect the positions of disease loci, lod scores are calculated at multiple chromosomal positions given trait and marker data on members of pedigrees. Exact lod score calculations are often impossible when the size of the pedigree and the number of markers are both large. In this case, a Markov Chain Monte Carlo (MCMC) approach provides an approximation. However, to provide accurate results, mixing performance is always a key issue in these MCMC methods. In this paper, we propose two methods to improve MCMC sampling and hence obtain more accurate lod score estimates in shorter computation time. The first improvement generalizes the block-Gibbs meiosis (M) sampler to multiple meiosis (MM) sampler in which multiple meioses are updated jointly, across all loci. The second one divides the computations on a large pedigree into several parts by conditioning on the haplotypes of some 'key' individuals. We perform exact calculations for the descendant parts where more data are often available, and combine this information with sampling of the hidden variables in the ancestral parts. Our approaches are expected to be most useful for data on a large pedigree with a lot of missing data. (c) 2007 S. Karger AG, Basel

  6. PyPedal, an open source software package for pedigree analysis

    Science.gov (United States)

    The open source software package PyPedal (http://pypedal.sourceforge.net/) was first released in 2002, and provided users with a set of simple tools for manipulating pedigrees. Its flexibility has been demonstrated by its used in a number of settings for large and small populations. After substantia...

  7. Systematic differences in the response of genetic variation to pedigree and genome-based selection methods

    NARCIS (Netherlands)

    Heidaritabar, M.; Vereijken, A.; Muir, W.M.; Meuwissen, T.H.E.; Cheng, H.; Megens, H.J.W.C.; Groenen, M.; Bastiaansen, J.W.M.

    2014-01-01

    Genomic selection (GS) is a DNA-based method of selecting for quantitative traits in animal and plant breeding, and offers a potentially superior alternative to traditional breeding methods that rely on pedigree and phenotype information. Using a 60¿K SNP chip with markers spaced throughout the

  8. Identification of Mendelian inconsistencies between SNP and pedigree Information of Sibs

    NARCIS (Netherlands)

    Calus, M.P.L.; Mulder, H.A.; Bastiaansen, J.W.M.

    2011-01-01

    Background Using SNP genotypes to apply genomic selection in breeding programs is becoming common practice. Tools to edit and check the quality of genotype data are required. Checking for Mendelian inconsistencies makes it possible to identify animals for which pedigree information and genotype

  9. Identification of Mendelian inconsistencies between SNP and pedigree information of sibs

    Directory of Open Access Journals (Sweden)

    Calus Mario PL

    2011-10-01

    Full Text Available Abstract Background Using SNP genotypes to apply genomic selection in breeding programs is becoming common practice. Tools to edit and check the quality of genotype data are required. Checking for Mendelian inconsistencies makes it possible to identify animals for which pedigree information and genotype information are not in agreement. Methods Straightforward tests to detect Mendelian inconsistencies exist that count the number of opposing homozygous marker (e.g. SNP genotypes between parent and offspring (PAR-OFF. Here, we develop two tests to identify Mendelian inconsistencies between sibs. The first test counts SNP with opposing homozygous genotypes between sib pairs (SIBCOUNT. The second test compares pedigree and SNP-based relationships (SIBREL. All tests iteratively remove animals based on decreasing numbers of inconsistent parents and offspring or sibs. The PAR-OFF test, followed by either SIB test, was applied to a dataset comprising 2,078 genotyped cows and 211 genotyped sires. Theoretical expectations for distributions of test statistics of all three tests were calculated and compared to empirically derived values. Type I and II error rates were calculated after applying the tests to the edited data, while Mendelian inconsistencies were introduced by permuting pedigree against genotype data for various proportions of animals. Results Both SIB tests identified animal pairs for which pedigree and genomic relationships could be considered as inconsistent by visual inspection of a scatter plot of pairwise pedigree and SNP-based relationships. After removal of 235 animals with the PAR-OFF test, SIBCOUNT (SIBREL identified 18 (22 additional inconsistent animals. Seventeen animals were identified by both methods. The numbers of incorrectly deleted animals (Type I error, were equally low for both methods, while the numbers of incorrectly non-deleted animals (Type II error, were considerably higher for SIBREL compared to SIBCOUNT. Conclusions

  10. Distribution of radioactive caesium in the population of Northern Sweden

    International Nuclear Information System (INIS)

    Wickman, G.; Johansson, L.; Eriksson, A.

    1989-01-01

    Long term surveys of a population living in a Cs-contaminated area, by muscle-tissue measurements from medicolegal autopsies, are cheap, simple and probably as accurate as whole-body measurements. Our parallel measurements of muscle concentration versus total body per gram potassium, indicate that it is possible to find consistent conversion factors to give total body content and internal absorbed dose. The great discrepancy in average total body content found by a whole body measurement survey when compared to our autopsy material measurements, indicates that severe underestimates can result from the voluntarism associated with the whole-body measurement technique. The average annual absorbed dose 1988-1989 from internally deposited Cs-137 in studied medium and high contaminated areas (10-80 kBq/m 2 ) obtained from our material is 50 μSv. The contribution from Cs-134 should be added. The resulting absorbed dose is still small compared to the external dose from the same isotopes which is roughly ten times higher. (orig.)

  11. Gender equality and health experiences : workplace patterns in Northern Sweden

    OpenAIRE

    Elwér, Sofia

    2013-01-01

    Gendered practices of working life create gender inequalities through horizontal and vertical gender segregation in work, which may lead to gender inequalities in health experiences. The workplace is an important part of the social circumstances under which health opportunities and constraints are shaped. The workplace has also been identified as an important arena for gender constructions. Still, there is a lack of research about the relations between workplace gender equality and health exp...

  12. International Uranium Resources Evaluation Project (IUREP) national favourability studies: Sweden

    International Nuclear Information System (INIS)

    1977-11-01

    Sweden, covers an area of approx. 450 000 square kilometers. It has a population of 8 millions. With few exceptions in the northern part the access can be regarded as good. A dense network of motorroads and railroad exists. The results obtained by the exploration works combined with other available geo-information permit a separation of two principal uranium provinces in Sweden. The first one is confined to sediments of Upper Cambrian and Lower Ordovician which appears in Southern Sweden and along the border of the Caledonian mountain range in Central Sweden. The uranium occurrence are stratiform, of blackshale type which occurs in the Peltura zone of Upper Cambrian or they are associated to a phosphatite-bearing unit of Lower Ordovician overlying the Cambrian shale formation. The distribution of uranium in Upper Cambrian rocks is in general dependant on their lithology which itself is related to the paleography. This conditions explain relatively higher uranium content of the shale from Billigen.The potential resources of the province are estimated at about 1 million tonnes uranium. The second uranium province, called Arjeplog-Arvidsjaur, situated immediately south of the Arctic circle, comprises one deposit - Pleutajokk - and a group of more than twenty occurrences of similar characteristics and age (1 700 - 1 800 my.). The results of the past exploration have shown that uranium is present in different types of rocks. Because of the presence of uranium in many of the pegmatites the possibility of the formation of large low grade deposits should be tested. Favourable areas are those regions where the geological conditions are similar to the geology of the Grenville province in Canada or the Damara belt of SW-Africa. Special studies are recommended on this subject

  13. Energy Foresight - Sweden in Europe

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    The IVA-project 'Energy Foresight - Sweden in Europe' deals with possibilities and problems associated with our energy future. We take it for granted that various forms of energy will always be available for a multitude of purposes and at acceptable prices. Sweden also places high demands on health and environmental protection issues when it comes to the production of power and heat. During the last few years the climate issue has been highlighted, which in turn will change the conditions for the use of alternative sources of energy. Carbon dioxide is the most important of the greenhouse gases, and it is closely associated with the burning of coal, oil, and natural gas. These fossil fuels play dominant roles in the world 's energy supply. Far-reaching measures to decrease carbon dioxide emissions will thus greatly affect the ways in which we use fossil fuels and non-carbon dioxide generating sources of energy. We have chosen a global starting point for our energy study. From there we will zoom in on the energy systems of Europe and Sweden. The climate issue demands global approach. Deregulation of electricity and gas markets, and the development of integrated European systems related to these energy sources, requires an international perspective on he Swedish energy system. Our project differs from earlier governmental energy studies in the sense that we are not trying to present the most likely, nor the most desirable energy future. Instead we have opted to draw up some illustrations of Sweden's future energy system, with Europe as a backdrop. The climate issue differentiates the scenarios. Our time perspective is 20 years, with glimpses 50 years ahead. On the 18th of February 2003, the Steering Group of Energy Foresight - Sweden in Europe, presented it's final report. The bulk of the work has been done in four panels. Their reflections and conclusions are presented in separate panel reports. The 12 factual reports present different

  14. Energy Foresight - Sweden in Europe

    International Nuclear Information System (INIS)

    2003-01-01

    The IVA-project 'Energy Foresight - Sweden in Europe' deals with possibilities and problems associated with our energy future. We take it for granted that various forms of energy will always be available for a multitude of purposes and at acceptable prices. Sweden also places high demands on health and environmental protection issues when it comes to the production of power and heat. During the last few years the climate issue has been highlighted, which in turn will change the conditions for the use of alternative sources of energy. Carbon dioxide is the most important of the greenhouse gases, and it is closely associated with the burning of coal, oil, and natural gas. These fossil fuels play dominant roles in the world 's energy supply. Far-reaching measures to decrease carbon dioxide emissions will thus greatly affect the ways in which we use fossil fuels and non-carbon dioxide generating sources of energy. We have chosen a global starting point for our energy study. From there we will zoom in on the energy systems of Europe and Sweden. The climate issue demands global approach. Deregulation of electricity and gas markets, and the development of integrated European systems related to these energy sources, requires an international perspective on he Swedish energy system. Our project differs from earlier governmental energy studies in the sense that we are not trying to present the most likely, nor the most desirable energy future. Instead we have opted to draw up some illustrations of Sweden's future energy system, with Europe as a backdrop. The climate issue differentiates the scenarios. Our time perspective is 20 years, with glimpses 50 years ahead. On the 18th of February 2003, the Steering Group of Energy Foresight - Sweden in Europe, presented it's final report. The bulk of the work has been done in four panels. Their reflections and conclusions are presented in separate panel reports. The 12 factual reports present different sources of energy, how hey are

  15. Exome sequencing of a pedigree with Tourette syndrome or chronic tic disorder.

    Science.gov (United States)

    Sundaram, Senthil K; Huq, Ahm M; Sun, Zhen; Yu, Wu; Bennett, Lindsey; Wilson, Benjamin J; Behen, Michael E; Chugani, Harry T

    2011-05-01

    Ten members of a 3-generation pedigree with 7 showing Tourette syndrome/chronic tic phenotype (TS-CTD) were evaluated with whole exome sequencing. We identified 3 novel, nonsynonymous single nucleotide variants in the MRPL3, DNAJC13, and OFCC1 genes that segregated with chronic tic phenotype. These variants were not present in 100 control subjects or in dbSNP/1000 Genomes databases. A novel variant in the 5' untranslated region of the OFCC1 gene was found in 2 TS-CTD patients from a different pedigree. Further studies will clarify the importance of variants in MRPL3, DNAJC13, and OFCC1 genes in TS. Copyright © 2011 American Neurological Association.

  16. Genetic drift. Descent, lineage, and pedigree of the Trojans in Homer's Iliad.

    Science.gov (United States)

    Bazopoulou-Kyrkanidou, Euterpe

    2007-12-15

    Homer's Iliad, is an epic poem that describes the last 70 days of the Trojan War, which was waged against the city of Troy by the Achaeans. Here, the descent, lineage, and the pedigree of the Trojans are presented. In the Illiad, they are said to have originated from Zeus. Beginning with him, the Trojan pedigree comprised 17 men in 8 generations with Dardanus, founder of Dardania in the second generation; Tros, King of the Trojans in the fourth generation; and the two heroes Hector and Aeneas in the eighth generation. In the seventh generation, Priam, as King of the Trojans, had a huge family, including 50 sons: 19 children with his wife Hecabe, other sons with many different wives, and some daughters as well. Hector, the first born, became leader of the Trojans. Hector's brother, Paris, in abducting Helen of Sparta, the wife of King Menelaus, caused the Trojan War to break out. (c) 2007 Wiley-Liss, Inc.

  17. Inbreeding trends and pedigree analysis of Bavarian mountain hounds, Hanoverian hounds and Tyrolean hounds.

    Science.gov (United States)

    Voges, S; Distl, O

    2009-10-01

    The objective of this study was to analyse genetic diversity for the three scent-hound breeds Bavarian mountain hound (BMH), Hanoverian hound (HH) and Tyrolean hound (TH) using all available pedigree information from scent-hound kennel clubs for these three breeds throughout Europe. The pedigree data of the BMH and the HH date back to 1912 and 1894, respectively. Pedigree data of the TH were available from the 1960s onwards. The reference populations included all BMH (n = 3231), HH (n = 1371) and TH (n = 1167) dogs registered between 1992 and 2004. Average generation intervals were 5.3 years for the BMH and 5.0 years for the HH and TH. Average inbreeding coefficients for the reference populations were 4.5%, 6.8% and 9.5% for the BMH, HH and TH. The effective numbers of founders, ancestors and founder genomes were lowest for the TH and highest for the BMH. The effective numbers of founder genomes were 10.9, 5.6 and 4.3 for the BMH, HH and TH. Effective population size was largest for the BMH with 72.7 effective breeding animals, followed by the HH with 50.9 and TH with 26.5. The most important ten ancestors had genetic contributions to the reference populations of 54.4%, 65.2% and 77.9% in the BMH, HH and TH. The results of our study indicate the need for careful breed management in these highly specialized hound breeds to maintain genetic diversity. European stud books should be established for these dog breeds in order to avoid inbreeding due to missing pedigree records.

  18. Does perfectionism in bipolar disorder pedigrees mediate associations between anxiety/stress and mood symptoms?

    OpenAIRE

    Corry, Justine; Green, Melissa; Roberts, Gloria; Fullerton, Janice M.; Schofield, Peter R.; Mitchell, Philip B.

    2017-01-01

    Background Bipolar disorder (BD) and the anxiety disorders are highly comorbid. The present study sought to examine perfectionism and goal attainment values as potential mechanisms of known associations between anxiety, stress and BD symptomatology. Measures of perfectionism and goal attainment values were administered to 269 members of BD pedigrees, alongside measures of anxiety and stress, and BD mood symptoms. Regression analyses were used to determine whether perfectionism and goal attain...

  19. KinLinks: Software Toolkit for Kinship Analysis and Pedigree Generation from NGS Datasets

    Science.gov (United States)

    2015-04-21

    combined into multi-generation 2 pedigrees via a set of heuristics to resolve relationship type (half siblings vs avuncular vs grandparent...this metric is able to differentiate parent- child relationships from siblings . • Kinship Coefficient as calculated by the KING algorithm [22]. The...second classifier predicts the exact relationship among a pair of samples (i.e. parent/ child , sibling , grandparent, avuncular, cousin, unrelated). Both

  20. The history of tuberculosis management in Sweden.

    Science.gov (United States)

    Wallstedt, Helen; Maeurer, Markus

    2015-03-01

    We review the history of TB in Sweden beginning in 1800, when 25% of mortality in Sweden was associated with TB. The Royal Family was involved in establishing dedicated sanatoria in Sweden to offer better diagnostics and clinical care. TB has declined in Sweden steadily, with some recent increases due to local spread of TB and challenging international and national socio-economical structures. Improved research and clinical knowledge is needed to diagnose and manage drug-susceptible as well as drug-resistant TB. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

  1. The History of Tuberculosis Management in Sweden

    Directory of Open Access Journals (Sweden)

    Helen Wallstedt

    2015-03-01

    Full Text Available We review the history of TB in Sweden beginning in 1800, when 25% of mortality in Sweden was associated with TB. The Royal Family was involved in establishing dedicated sanatoria in Sweden to offer better diagnostics and clinical care. TB has declined in Sweden steadily, with some recent increases due to local spread of TB and challenging international and national socio-economical structures. Improved research and clinical knowledge is needed to diagnose and manage drug-susceptible as well as drug-resistant TB.

  2. A powerful parent-of-origin effects test for qualitative traits on X chromosome in general pedigrees.

    Science.gov (United States)

    Zou, Qi-Lei; You, Xiao-Ping; Li, Jian-Long; Fung, Wing Kam; Zhou, Ji-Yuan

    2018-01-05

    Genomic imprinting is one of the well-known epigenetic factors causing the association between traits and genes, and has generally been examined by detecting parent-of-origin effects of alleles. A lot of methods have been proposed to test for parent-of-origin effects on autosomes based on nuclear families and general pedigrees. Although these parent-of-origin effects tests on autosomes have been available for more than 15 years, there has been no statistical test developed to test for parent-of-origin effects on X chromosome, until the parental-asymmetry test on X chromosome (XPAT) and its extensions were recently proposed. However, these methods on X chromosome are only applicable to nuclear families and thus are not suitable for general pedigrees. In this article, we propose the pedigree parental-asymmetry test on X chromosome (XPPAT) statistic to test for parent-of-origin effects in the presence of association, which can accommodate general pedigrees. When there are missing genotypes in some pedigrees, we further develop the Monte Carlo pedigree parental-asymmetry test on X chromosome (XMCPPAT) to test for parent-of-origin effects, by inferring the missing genotypes given the observed genotypes based on a Monte Carlo estimation. An extensive simulation study has been carried out to investigate the type I error rates and the powers of the proposed tests. Our simulation results show that the proposed methods control the size well under the null hypothesis of no parent-of-origin effects. Moreover, XMCPPAT substantially outperforms the existing tests and has a much higher power than XPPAT which only uses complete nuclear families (with both parents) from pedigrees. We also apply the proposed methods to analyze rheumatoid arthritis data for their practical use. The proposed XPPAT and XMCPPAT test statistics are valid and powerful in detecting parent-of-origin effects on X chromosome for qualitative traits based on general pedigrees and thus are recommended.

  3. Whole-genome characterization in pedigreed non-human primates using Genotyping-By-Sequencing and imputation.

    OpenAIRE

    Cervera-Juanes, Rita; Vinson, Amanda; Ferguson, Betsy; Carbone, Lucia; Spindel, Eliot; Mccouch, Susan; Spindel, Jennifer; Nevonen, Kimberly; Letaw, John; Raboin, Michael; Bimber, Ben

    2016-01-01

    Background: Rhesus macaques are widely used in biomedical research, but the application of genomic information in this species to better understand human disease is still undeveloped. Whole-genome sequence (WGS) data in pedigreed macaque colonies could provide substantial experimental power, but the collection of WGS data in large cohorts remains a formidable expense. Here, we describe a cost-effective approach that selects the most informative macaques in a pedigree for whole-genome sequenci...

  4. [Consensus on clinical diagnosis, treatment and pedigree management of hereditary colorectal cancer in China].

    Science.gov (United States)

    2018-01-23

    Hereditary colorectal cancer can be divded into two categories based on the presence or absence of polyps. The first category is characterized by the development of polyposis, which includes familial adenomatous polyposis (FAP); The second category is nonpolyposis colorectal cancer, which is represented by Lynch syndrome. "Consensus on clinical diagnosis, treatment and pedigree management of hereditary colorectal cancer in China" developed by the Genetics Group of the Committee of Colorectal Cancer, Chinese Anti-cancer Association, is composed of three sections, including hereditary nonpolyposis syndrome, polyposis syndrome as well as genetic evaluation of hereditary colorectal cancer. The consensus aims to provide recommendations on management of the respective hereditary syndromes in terms of definition, clinical and pathological features, diagnostic standards, treatment, and follow-ups. In addition to describing diagnostic and treatment strategies, prophylactic treatment as well as genetic screening and pedigree monitoring is highly recommended. Through the establishment of this expert consensus, we hope to promote better understanding of hereditary colorectal cancer for clinicians and encourage standardized treatment through multidisciplinery approaches, eventually improving clinical treatment and pedigree management of hereditary colorectal cancer in China.

  5. Machado-Joseph disease in pedigrees of Azorean descent is linked to chromosome 14.

    Science.gov (United States)

    St George-Hyslop, P; Rogaeva, E; Huterer, J; Tsuda, T; Santos, J; Haines, J L; Schlumpf, K; Rogaev, E I; Liang, Y; McLachlan, D R

    1994-07-01

    A locus for Machado-Joseph disease (MJD) has recently been mapped to a 30-cM region of chromosome 14q in five pedigrees of Japanese descent. MJD is a clinically pleomorphic neurodegenerative disease that was originally described in subjects of Azorean descent. In light of the nonallelic heterogeneity in other inherited spinocerebellar ataxias, we were interested to determine if the MJD phenotype in Japanese and Azorean pedigrees arose from mutations at the same locus. We provide evidence that MJD in five pedigrees of Azorean descent is also linked to chromosome 14q in an 18-cM region between the markers D14S67 and AACT (multipoint lod score +7.00 near D14S81). We also report molecular evidence for homozygosity at the MJD locus in an MJD-affected subject with severe, early-onset symptoms. These observations confirm the initial report of linkage of MJD to chromosome 14; suggest that MJD in Japanese and Azorean subjects may represent allelic or identical mutations at the same locus; and provide one possible explanation (MJD gene dosage) for the observed phenotypic heterogeneity in this disease.

  6. Bound volatile precursors in genotypes in the pedigree of 'Marion' blackberry (Rubus sp.).

    Science.gov (United States)

    Du, Xiaofen; Finn, Chad E; Qian, Michael C

    2010-03-24

    Glycosidically bound volatiles and precursors in genotypes representing the pedigree for 'Marion' blackberry were investigated over two growing seasons. The volatile precursors were isolated using a C18 solid-phase extraction column. After enzymatic hydrolysis, the released volatiles were analyzed using stir bar sorptive extraction gas chromatography-mass spectrometry (GC-MS) and direct microvial insert thermal desorption GC-MS. The most abundant volatile precursors in the genotypes were alcohols, followed by shikimic acid derivatives. High amounts of furanone glycosides were also detected, while norisoprenoids only existed in a small amount in blackberries. The volatile precursor composition in the genotypes in the 'Marion' pedigree was very similar to their free volatile distribution. 'Logan' and 'Olallie' predominantly had bound norisoprenoids. Wild 'Himalaya' predominated with terpene alcohol and furaneol glycosides, whereas 'Santiam' and 'Chehalem' contained a high level of terpene alcohol glycosides. A similar inheritance pattern was also observed for some volatile precursors in the genotypes in the 'Marion' pedigree. A high content of linalool, hydroxylinalool, and alpha-ionol glycosides in 'Olallie' and a low content in 'Chehalem' resulted in a moderate level in their offspring 'Marion', while a low content of (E)-linalool oxide precursor in 'Olallie' and a high content in 'Chehalem' also resulted in a moderate level in 'Marion'. However, the concentration of furaneol glycosides in 'Marion' exceeded that of its two parents.

  7. Pedigree and genomic analyses of feed consumption and residual feed intake in laying hens.

    Science.gov (United States)

    Wolc, Anna; Arango, Jesus; Jankowski, Tomasz; Settar, Petek; Fulton, Janet E; O'Sullivan, Neil P; Fernando, Rohan; Garrick, Dorian J; Dekkers, Jack C M

    2013-09-01

    Efficiency of production is increasingly important with the current escalation of feed costs and demands to minimize the environmental footprint. The objectives of this study were 1) to estimate heritabilities for daily feed consumption and residual feed intake and their genetic correlations with production and egg-quality traits; 2) to evaluate accuracies of estimated breeding values from pedigree- and marker-based prediction models; and 3) to localize genomic regions associated with feed efficiency in a brown egg layer line. Individual feed intake data collected over 2-wk trial periods were available for approximately 6,000 birds from 8 generations. Genetic parameters were estimated with a multitrait animal model; methods BayesB and BayesCπ were used to estimate marker effects and find genomic regions associated with feed efficiency. Using pedigree information, feed efficiency was found to be moderately heritable (h(2) = 0.46 for daily feed consumption and 0.47 for residual feed intake). Hens that consumed more feed and had greater residual feed intake (lower efficiency) had a genetic tendency to lay slightly more eggs with greater yolk weights and albumen heights. Regions on chromosomes 1, 2, 4, 7, 13, and Z were found to be associated with feed intake and efficiency. The accuracy from genomic prediction was higher and more persistent (better maintained across generations) than that from pedigree-based prediction. These results indicate that genomic selection can be used to improve feed efficiency in layers.

  8. Validation of DNA-based identification software by computation of pedigree likelihood ratios.

    Science.gov (United States)

    Slooten, K

    2011-08-01

    Disaster victim identification (DVI) can be aided by DNA-evidence, by comparing the DNA-profiles of unidentified individuals with those of surviving relatives. The DNA-evidence is used optimally when such a comparison is done by calculating the appropriate likelihood ratios. Though conceptually simple, the calculations can be quite involved, especially with large pedigrees, precise mutation models etc. In this article we describe a series of test cases designed to check if software designed to calculate such likelihood ratios computes them correctly. The cases include both simple and more complicated pedigrees, among which inbred ones. We show how to calculate the likelihood ratio numerically and algebraically, including a general mutation model and possibility of allelic dropout. In Appendix A we show how to derive such algebraic expressions mathematically. We have set up these cases to validate new software, called Bonaparte, which performs pedigree likelihood ratio calculations in a DVI context. Bonaparte has been developed by SNN Nijmegen (The Netherlands) for the Netherlands Forensic Institute (NFI). It is available free of charge for non-commercial purposes (see www.dnadvi.nl for details). Commercial licenses can also be obtained. The software uses Bayesian networks and the junction tree algorithm to perform its calculations. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

  9. Partitioning the variability of fasting plasma glucose levels in pedigrees. Genetic and environmental factors.

    Science.gov (United States)

    Boehnke, M; Moll, P P; Kottke, B A; Weidman, W H

    1987-04-01

    Fasting plasma glucose measurements made in 1972-1977 on normoglycemic individuals in three-generation Caucasian pedigrees from Rochester, Minnesota were analyzed. The authors determined the contributions of polygenic loci and environmental factors to fasting plasma glucose variability in these pedigrees. To that end, fasting plasma glucose measurements were normalized by an inverse normal scores transformation and then regressed separately for males and females on measured concomitants including age, body mass index (weight/height2), season of measurement, sex hormone use, and diuretic use. The authors found that 27.7% of the variability in normalized fasting plasma glucose in these pedigrees is explained by these measured concomitants. Subsequent variance components analysis suggested that unmeasured polygenic loci and unmeasured shared environmental factors together account for at least an additional 36.7% of the variability in normalized fasting plasma glucose, with genes alone accounting for at least 27.3%. These results are consistent with the known familiality of diabetes, for which fasting plasma glucose level is an important predictor. Further, these familial factors provide an explanation for at least half the variability in normalized fasting plasma glucose which remains after regression on known concomitants.

  10. ePedigree Traceability System for the Agricultural Food Supply Chain to Ensure Consumer Health

    Directory of Open Access Journals (Sweden)

    Umar Farooq

    2016-08-01

    Full Text Available Sustainability relies on the environmental, social and economical systems: the three pillars of sustainability. The social sustainability mostly advocates the people’s welfare, health, safety, and quality of life. In the agricultural food industry, the aspects of social sustainability, such as consumer health and safety have gained substantial attention due to the frequent cases of food-borne diseases. The food-borne diseases due to the food degradation, chemical contamination and adulteration of food products pose a serious threat to the consumer’s health, safety, and quality of life. To ensure the consumer’s health and safety, it is essential to develop an efficient system which can address these critical social issues in the food distribution networks. This research proposes an ePedigree (electronic pedigree traceability system based on the integration of RFID and sensor technology for real-time monitoring of the agricultural food to prevent the distribution of hazardous and adulterated food products. The different aspects regarding implementation of the proposed system in food chains are analyzed and a feasible integrated solution is proposed. The performance of the proposed system is evaluated and finally, a comprehensive analysis of the proposed ePedigree system’s impact on the social sustainability in terms of consumer health and safety is presented.

  11. Aespoe hard rock laboratory Sweden

    International Nuclear Information System (INIS)

    1992-01-01

    The aim of the new Aespoe hard rock laboratory is to demonstrate state of the art of technology and evaluation methods before the start of actual construction work on the planned deep repository for spent nuclear fuel. The nine country OECD/NEA project in the Stripa mine in Sweden has been an excellent example of high quality international research co-operation. In Sweden the new Aespoe hard rock laboratory will gradually take over and finalize this work. SKB very much appreciates the continued international participation in Aespoe which is of great value for the quality efficiency, and confidence in this kind of work. We have invited a number of leading experts to this first international seminar to summarize the current state of a number of key questions. The contributions show the great progress that has taken place during the years. The results show that there is a solid scientific basis for using this knowledge on site specific preparation and work on actual repositories. (au)

  12. A central spent fuel storage in Sweden

    International Nuclear Information System (INIS)

    Gustafsson, B.; Hagberth, R.

    1978-01-01

    A planned central spent fuel storage facility in Sweden is described. The nuclear power program and quantities of spent fuel generated in Sweden is discussed. A general description of the facility is given with emphasis on the lay-out of the buildings, transport casks and fuel handling. Finally a possible design of a Swedish transportation system is discussed. (author)

  13. ASEA reduces nuclear waste in Sweden

    International Nuclear Information System (INIS)

    Anon.

    1977-01-01

    ASEA, the worldwide manufacturer of electrical and mechanical equipment with headquarters in Vasteras, Sweden, is working on the development of a method using hot isostatic pressing for the safe containment and storage of nuclear waste. This development work is being carried out at the company's High-Pressure Laboratory at Robertsfors, in the north of Sweden

  14. Public Procurement of Innovation in Sweden

    DEFF Research Database (Denmark)

    Rolfstam, Max; Ågren, Robert

    2014-01-01

    Sweden is often thought of as a country with a strong tradition for using public procurement as a means to stimulate innovation. Early on, Sweden recognized and developed procedures for using public procurement as a technologydevelopment tool. After a period where emphasis was put on this aspect ...... government authorities to engage in public procurement for innovation, and by issuing guidance on the topic.......Sweden is often thought of as a country with a strong tradition for using public procurement as a means to stimulate innovation. Early on, Sweden recognized and developed procedures for using public procurement as a technologydevelopment tool. After a period where emphasis was put on this aspect...... of public procurement Sweden dropped many policy initiatives within this field. This was in part due to neo-liberal movements during the 1980s which in interaction with a distributed institutional setup led to the removal of incentives for a procuring authority to engage in public procurement of innovation...

  15. Effect of wind turbine mortality on noctule bats in Sweden: predictions from a simple population model

    Energy Technology Data Exchange (ETDEWEB)

    Rydell, Jens; Hedenstroem, Anders; Green, Martin

    2011-07-01

    Full text: The noctule bat Nyctalus noctula is apparently the species most seriously affected by wind turbine mortality in northern Europe. It occurs in south Sweden up to about 60oN, although the abundance is much higher in lowland agricultural areas than in forests. We used a recent estimate of 90 000 individuals as the population size in Sweden, and assumed a stable starting population not affected by mortality from wind turbines. In the absence of data from Sweden, we used demographic data and fatality rates at wind turbines (0.9 noctules/turbine/year) obtained in eastern Germany. Population development up to year 2020 was calculated, based on the current estimate of wind farm development in Sweden; ca. 1000 present and 2500 additional turbines within the area of noctule distribution. The results suggest that the additional mortality at wind turbines may affect the noctule bat in Sweden at the population level. However, the effect will probably be small, particularly in comparison with other anthropogenic sources. We are currently using the model to predict the effect on other bat species and birds. (Author)

  16. Research on Pentecostalism in Sweden

    Directory of Open Access Journals (Sweden)

    Jan-Åke Alvarsson

    2015-05-01

    Full Text Available This article aims to orientate and introduce potential researchers into Swedish Pentecostal movements, or those who wish to provide an overview of Scandinavian Christianity, by giving a brief summary of the history of Pentecostalism in Sweden and an overview of the main academic monographs that have been produced on this particular branch of Christianity. The idea is to highlight areas where we find relevant research and to point to areas into which there has been little or no investigation. Following, by way of introduction, a brief historical sketch, there is a note on spirituality before we are given a review of some thirty major academic works on the subject that a potential researcher would need to take into consideration.

  17. Chernobyl - its impact on Sweden

    International Nuclear Information System (INIS)

    1986-08-01

    In case of radiological emergency in Sweden, the Swedish National Institute of Radiation Protection (SSI) has the responsability of organizing a special task force with experts both from SSI and from other authorities. Reports of increased radiation levels reached SSI around 10 am on April 28, 1986, and the task force convened at 1030 am. A large number of measurements were made all over the country, and temporary grazing restrictions were imposed so as to aviod excessive doses from the food chain grass-cow-milk. Attention is now concentrated on regions with high cesium activity and on foodstuffs in general. A very tentative estimate of the collective dose commiment is 10 000 man.Sv. It turned out that the general public was not always satisfied with the information provided by the authorities, in spite of complete openness (Author)

  18. Radioactive wast management in Sweden

    International Nuclear Information System (INIS)

    Sivintsev, Yu.V.

    1985-01-01

    A system under development and partially realized of NPP radioactive waste management in Sweden up to spent-fuel disposal in underground storage is described. The system implies that the spent fuel after unloading from a reactor is stored at the NPP in water shielded tanks. Then fuel assemblies (FA) are transforted by a special ship, being operated since 1982, to the CLAB central storage. In CLAB water pools lacated in underground granite openings fuel assemblies will be stored for 40 years. CLAB is suggested to be put in operation in 1985. At the next stage FA are transported from CLAB to the canning set-up (located on the ground above the under ground disposal). Hot isostatic pressing is used for hermetization as a method allowing to make monolithic copper containers with a storage time of about 1 mln years. Sealed copper containers will be put into a burial ground sited in crystal rocks

  19. Radon in dwellings in Sweden

    International Nuclear Information System (INIS)

    Swedjemark, G.A.

    1980-01-01

    Studies on specific activities in building materials, gamma-radiation levels in dwellings, the concentrations of radon and daughters in the air indoors and the concentration of radon in tap water are in progress in Sweden. On the basis of these investigations and of the investigation of Hultqvist from the beginning of the 1950's, an attempt has been made to show how the radiation doses in dwellings have changed or may be changed by human activities and what these changes imply in terms of collective dose. The annual collective absorbed dose in the basal cells of the critical bronchial region have increased from 11 x 10 3 man-Gy for the occupants of dwellings existing in 1950 to 25 x 10 3 man-Gy for dwellings existing in 1975

  20. Incidence of hyperthyroidism in Sweden.

    Science.gov (United States)

    Abraham-Nordling, Mirna; Byström, Kristina; Törring, Ove; Lantz, Mikael; Berg, Gertrud; Calissendorff, Jan; Nyström, Helena Filipsson; Jansson, Svante; Jörneskog, Gun; Karlsson, F Anders; Nyström, Ernst; Ohrling, Hans; Orn, Thomas; Hallengren, Bengt; Wallin, Göran

    2011-12-01

    The incidence of hyperthyroidism has been reported in various countries to be 23-93/100,000 inhabitants per year. This extended study has evaluated the incidence for ~40% of the Swedish population of 9 million inhabitants. Sweden is considered to be iodine sufficient country. All patients including children, who were newly diagnosed with overt hyperthyroidism in the years 2003-2005, were prospectively registered in a multicenter study. The inclusion criteria are as follows: clinical symptoms and/or signs of hyperthyroidism with plasma TSH concentration below 0.2 mIE/l and increased plasma levels of free/total triiodothyronine and/or free/total thyroxine. Patients with relapse of hyperthyroidism or thyroiditis were not included. The diagnosis of Graves' disease (GD), toxic multinodular goiter (TMNG) and solitary toxic adenoma (STA), smoking, initial treatment, occurrence of thyroid-associated eye symptoms/signs, and demographic data were registered. A total of 2916 patients were diagnosed with de novo hyperthyroidism showing the total incidence of 27.6/100,000 inhabitants per year. The incidence of GD was 21.0/100,000 and toxic nodular goiter (TNG=STA+TMNG) occurred in 692 patients, corresponding to an annual incidence of 6.5/100,000. The incidence was higher in women compared with men (4.2:1). Seventy-five percent of the patients were diagnosed with GD, in whom thyroid-associated eye symptoms/signs occurred during diagnosis in every fifth patient. Geographical differences were observed. The incidence of hyperthyroidism in Sweden is in a lower range compared with international reports. Seventy-five percent of patients with hyperthyroidism had GD and 20% of them had thyroid-associated eye symptoms/signs during diagnosis. The observed geographical differences require further studies.

  1. Genetic diversity analysis of two commercial breeds of pigs using genomic and pedigree data.

    Science.gov (United States)

    Zanella, Ricardo; Peixoto, Jane O; Cardoso, Fernando F; Cardoso, Leandro L; Biegelmeyer, Patrícia; Cantão, Maurício E; Otaviano, Antonio; Freitas, Marcelo S; Caetano, Alexandre R; Ledur, Mônica C

    2016-03-30

    Genetic improvement in livestock populations can be achieved without significantly affecting genetic diversity if mating systems and selection decisions take genetic relationships among individuals into consideration. The objective of this study was to examine the genetic diversity of two commercial breeds of pigs. Genotypes from 1168 Landrace (LA) and 1094 Large White (LW) animals from a commercial breeding program in Brazil were obtained using the Illumina PorcineSNP60 Beadchip. Inbreeding estimates based on pedigree (F x) and genomic information using runs of homozygosity (F ROH) and the single nucleotide polymorphisms (SNP) by SNP inbreeding coefficient (F SNP) were obtained. Linkage disequilibrium (LD), correlation of linkage phase (r) and effective population size (N e ) were also estimated. Estimates of inbreeding obtained with pedigree information were lower than those obtained with genomic data in both breeds. We observed that the extent of LD was slightly larger at shorter distances between SNPs in the LW population than in the LA population, which indicates that the LW population was derived from a smaller N e . Estimates of N e based on genomic data were equal to 53 and 40 for the current populations of LA and LW, respectively. The correlation of linkage phase between the two breeds was equal to 0.77 at distances up to 50 kb, which suggests that genome-wide association and selection should be performed within breed. Although selection intensities have been stronger in the LA breed than in the LW breed, levels of genomic and pedigree inbreeding were lower for the LA than for the LW breed. The use of genomic data to evaluate population diversity in livestock animals can provide new and more precise insights about the effects of intense selection for production traits. Resulting information and knowledge can be used to effectively increase response to selection by appropriately managing the rate of inbreeding, minimizing negative effects of inbreeding

  2. A comparison of different algorithms for phasing haplotypes using Holstein cattle genotypes and pedigree data.

    Science.gov (United States)

    Miar, Younes; Sargolzaei, Mehdi; Schenkel, Flavio S

    2017-04-01

    Phasing genotypes to haplotypes is becoming increasingly important due to its applications in the study of diseases, population and evolutionary genetics, imputation, and so on. Several studies have focused on the development of computational methods that infer haplotype phase from population genotype data. The aim of this study was to compare phasing algorithms implemented in Beagle, Findhap, FImpute, Impute2, and ShapeIt2 software using 50k and 777k (HD) genotyping data. Six scenarios were considered: no-parents, sire-progeny pairs, sire-dam-progeny trios, each with and without pedigree information in Holstein cattle. Algorithms were compared with respect to their phasing accuracy and computational efficiency. In the studied population, Beagle and FImpute were more accurate than other phasing algorithms. Across scenarios, phasing accuracies for Beagle and FImpute were 99.49-99.90% and 99.44-99.99% for 50k, respectively, and 99.90-99.99% and 99.87-99.99% for HD, respectively. Generally, FImpute resulted in higher accuracy when genotypic information of at least one parent was available. In the absence of parental genotypes and pedigree information, Beagle and Impute2 (with double the default number of states) were slightly more accurate than FImpute. Findhap gave high phasing accuracy when parents' genotypes and pedigree information were available. In terms of computing time, Findhap was the fastest algorithm followed by FImpute. FImpute was 30 to 131, 87 to 786, and 353 to 1,400 times faster across scenarios than Beagle, ShapeIt2, and Impute2, respectively. In summary, FImpute and Beagle were the most accurate phasing algorithms. Moreover, the low computational requirement of FImpute makes it an attractive algorithm for phasing genotypes of large livestock populations. Copyright © 2017 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  3. Forecasting Model of Risk of Cancer in Lung Cancer Pedigree in a Case-control Study

    Directory of Open Access Journals (Sweden)

    Huan LIN

    2011-07-01

    Full Text Available Background and objective Annual lung screening using spiral computed tomography (CT, has a high sensitivity of detecting early lung cancer (LC, but its high rates of false-positive often lead to unnecessary surgery. The aim of this study is to create a forecasting model of high risk individuals to lung cancer. Methods The pathologic diagnoses of LC in Guangdong Lung Cancer Institute were consecutively chosen as the probands. All the members of the first-degree relatives of probands' and their spouses' were enrolled in this study. These pedigrees consisted of 633 probands' pedigrees and 565 spouses' pedigrees. Unless otherwise stated, analyses were performed using the SPSS 17.0 statistical software package. Results Compared with the control, a family history of carcinoma in first-degree relatives was significantly associated with LC risk (OR=1.71, P<0.001, the sub-group of either one infected individual or more than two infected individuals in first-degree relatives showed significantly statistical differences (P=0.005, P=0.002. In the forecasting model, the risk compared to that in Chinese population was from 0.38 to 63.08 folds. In the population whose risk was more than 10 times to the Chinese population, the accuracy rate of prediction was 88.1%. Conclusion A family history of carcinoma in first-degree relatives was significantly associated with increased LC risk. The more infected individuals exist in first-degree relatives, the more risk was showed. In the forecasting model, smokers especially heavy ones whose risk were more than 10 times to the Chinese population should be receive annual screening. The population are positive at least any two conditions which including male, lung disease history, occupation expose and history of cancer in first-degree relative.

  4. Inbreeding and Genetic Diversity in Three Imported Swine Breeds in China Using Pedigree Data

    Directory of Open Access Journals (Sweden)

    G. Q. Tang

    2013-06-01

    Full Text Available The accumulation of inbreeding and the loss of genetic diversity is a potential problem in the modern swine breeds in China. Therefore, the purpose of this study was to analyze the pedigrees of Chinese Duroc (CD, Landrace (CL and Yorkshire (CY swine to estimate the past and current rates of inbreeding, and to identify the main causes of genetic diversity loss. Pedigree files from CD, CL and CY containing, 4529, 16,776 and 22,600 records, respectively, were analyzed. Pedigree completeness indexes of the three breeds, accounting for one generation back, were 83.72, 93.93 and 93.59%, respectively. The estimated average annual inbreeding rates for CD, CL and CY in recent three years were 0.21, 0.19 and 0.13%, respectively. The estimated average percentage of genetic diversity loss within each breed in recent three years was about 8.92, 2.19, and 3.36%, respectively. The average relative proportion of genetic diversity loss due to unequal contributions of founders in CD, CL and CY was 69.09, 57.95 and 60.57%, and due to random genetic drift was 30.91, 42.05 and 39.43%, respectively. The estimated current effective population size for CD, CL and CY was 76, 117 and 202, respectively. Therefore, CD has been found to have lost considerable genetic diversity, demanding priority for optimizing the selection and mating to control future coancestry and inbreeding. Unequal contribution of founders was a major cause of genetic diversity loss in Chinese swine breeds and random genetic drift also showed substantial impact on the loss of diversity.

  5. Molecular Reconstruction of an Old Pedigree of Diploid and Triploid Hydrangea macrophylla Genotypes

    Directory of Open Access Journals (Sweden)

    Peter Hempel

    2018-04-01

    Full Text Available The ornamental crop species Hydrangea macrophylla exhibits diploid and triploid levels of ploidy and develops lacecap (wild type or mophead inflorescences. In order to characterize a H. macrophylla germplasm collection, we determined the inflorescence type and the 2C DNA content of 120 plants representing 43 cultivars. We identified 78 putative diploid and 39 putative triploid plants by flow cytometry. In our collection 69 out of 98 flowering plants produced lacecap inflorescences, whereas 29 plants developed mophead inflorescences. Surprisingly, 12 cultivars included diploid as well as triploid plants, while 5 cultivars contained plants with different inflorescence types. We genotyped this germplasm collection using 12 SSR markers that detected 2–7 alleles per marker, and identified 51 different alleles in this collection. We detected 62 distinct fingerprints, revealing a higher genetic variation than the number of cultivars suggested. Only one genotype per cultivar is expected due to the vegetative propagation of Hydrangea cultivars; however we identified 25 cultivars containing 2–4 different genotypes. These different genotypes explained the variation in DNA content and inflorescence type. Diploid and triploid plants with the same cultivar name were exclusively mix-ups. We therefor assume, that 36% of the tested plants were mislabeled. Based on the “Wädenswil” pedigree, which includes 31 of the tested cultivars, we predicted cultivar-specific fingerprints and identified at least 21 out of 31 cultivars by SSR marker-based reconstruction of the “Wädenswil” pedigree. Furthermore, we detected 4 putative interploid crosses between diploid and triploid plants in this pedigree. These interploid crosses resulted in diploid or/and triploid offspring, suggesting that crosses with triploids were successfully applied in breeding of H. macrophylla.

  6. Optimal Genetic Contribution Selection in Danish Holstein Depends on Pedigree Qualtiy

    DEFF Research Database (Denmark)

    Sørensen, M K; Sørensen, A C; Baumung, R

    2008-01-01

    . In the analyses earlier breeding decisions were considered by including all AI waiting- and young bulls and contract matings. Twenty potential sires, 2169 potential dams, 1421 AI-bulls and 754 contract matings plus pedigree animals were included. Results showed that the outcome was very dependent on quality...... the increase in future inbreeding. The more weight put on the average additive genetic relationship in next generation relative to genetic merit, the lower the average merit of the matings, and the lower average additive genetic relationship among the chosen matings and the present breeding animals...

  7. Familial atrophia maculosa varioliformis cutis: first case report from the Indian subcontinent with pedigree analysis.

    Science.gov (United States)

    Goyal, Tarang; Varshney, Anupam; Bakshi, S K

    2012-01-01

    Familial atrophia maculosa varioliformis cutis is a very rare disorder with less than 28 cases being reported in the literature worldwide and remains a mystery both as far as genetics and the virtue of its pathogenesis is concerned. We present a case of mother and son, both having this disorder with presentations unique in terms of sites involved and try to draw a five generations pedigree chart for the same. We further support its inheritance pattern as autosomal dominant. Also, we propose oral isotretinoin as an effective treatment modality for the same.

  8. Familial atrophia maculosa varioliformis cutis: First case report from the Indian subcontinent with pedigree analysis

    Directory of Open Access Journals (Sweden)

    Tarang Goyal

    2012-01-01

    Full Text Available Familial atrophia maculosa varioliformis cutis is a very rare disorder with less than 28 cases being reported in the literature worldwide and remains a mystery both as far as genetics and the virtue of its pathogenesis is concerned. We present a case of mother and son, both having this disorder with presentations unique in terms of sites involved and try to draw a five generations pedigree chart for the same. We further support its inheritance pattern as autosomal dominant. Also, we propose oral isotretinoin as an effective treatment modality for the same.

  9. Structural health monitoring of a concrete bridge in Sweden

    Science.gov (United States)

    Enochsson, Ola; Täljsten, Björn; Olofsson, Thomas

    2006-03-01

    Over the past decade the interests in upgrading, assessment and maintenance of our ageing infrastructure has grown avalanche-like. The main reason is economical aspects but also reasons due to accessibility environmental consideration play a vital role. Recently the Swedish and Norwegian Railway Association decided to upgrade the Iron Ore Line "Malmbanan", a railway line for transportation of iron from northern Sweden to the coasts of Norway and Sweden. Here the owner wanted to increase the axle loads from 25 to 30 tons to reduce the transportation costs. In one of the cases, the Luossajokk Bridge, a recalculation according to design codes showed that the increased axle loads would exceed the yield limit in the reinforcement. Before any decision was taken regarding strengthening or replacing the bridge an assessment with probabilistic methods was used. It appeared that the bridge could carry the higher load with a safety index β >= 4.7 for reasonable assumptions of the load distributions. A measurement system was installed to check the real worst placement of the new iron ore locomotive (IORE), and the actually level of strains in the reinforcement for the worst load case1. It was shown that the strain level was far from critical and that the evaluated worst placement of the locomotive was almost correct. To assure a reliable transportation a long term monitoring program was arranged to check the development of strains with time. Examples from the probabilistic evaluation and the monitoring of the bridge are given and discussed.

  10. Mechanical properties of granitic rocks from Gideaa, Sweden

    International Nuclear Information System (INIS)

    Ljunggren, C.; Stephansson, O.; Alm, O.; Hakami, H.; Mattila, U.

    1985-10-01

    The elastic and mechanical properties were determined for two rock types from the Gideaa study area. Gideaa is located approximately 30 km north-east of Oernskoeldsvik, Northern Sweden. The rock types that were tested were migmatitic gneiss and migmatitic granite. The following tests were conducted: - sound velocity measurements; - uniaxial compression tests with acoustic emission recording; - brazilian disc tests; - triaxial tests; - three point bending tests. All together, 12 rock samples were tested with each test method. Six samples of these were migmatic gneiss and six samples were migmatitic granite. The result shows that the migmatitic gneiss has varying strength properties with low compressive strength in comparison with its high tensile strength. The migmatitic granite, on the other hand, is found to have parameter values similar to other granitic rocks. With 15 refs. (Author)

  11. Energy in Sweden. Facts and figures 2005

    International Nuclear Information System (INIS)

    2005-12-01

    Energy in Sweden. Facts and Figures 2005 contains the tabular data for most of the diagrams in the main publication. These data consist primarily of the results of the Agency's processing of basic data from Statistics Sweden. Facts and Figures is available at www.stem.se in pdf- and excel file formats. With effect from the 2001 edition, statistics are of preliminary character for the two preceding years (2003 and 2004). Breakdowns into certain types of fuels vary somewhat depending on whether preliminary or final data has been used. Further information about the statistics can be found in Energy in Sweden, chapter 8 Energy Facts

  12. Occupational Gender Composition and Wages in Sweden

    OpenAIRE

    Hansen, Jörgen; Wahlberg, Roger

    2000-01-01

    We estimate the relationship between wages and occupational gender segregation in Sweden. Because of high wage equality in Sweden compared to the U.S., we expect a lower wage penalty of job femaleness in Sweden than in the U.S. Our results supports this hypothesis. We also investigate how the unexplained gender wage gap vary across occupations and find that this gap is smallest in male dominated jobs and largest in female dominated jobs. Finally, we investigate whether the female wage-experie...

  13. Renewable Energy Policy Fact sheet - Sweden

    International Nuclear Information System (INIS)

    2017-09-01

    The EurObserv'ER policy profiles give a snapshot of the renewable energy policy in the EU Member States. Sweden surpassed its 2020 nationally binding renewable energy in 2013. Main support measures to promote renewable energy in Sweden consists of a quota system, various tax regulation mechanisms and subsidy schemes. Sweden has a joint support scheme with Norway, thus being the first EU Member State to implement a cooperation mechanism, as defined under the 2009 EU Renewable Energy Directive. The Swedish coalition government has agreed on a target of 100% renewable electricity production by 2040

  14. Sweden and the NEGP: A Pilot Study of the North European Gas Pipeline and Sweden's Dependence on Russian Energy

    Energy Technology Data Exchange (ETDEWEB)

    Larsson, Robert L

    2006-06-15

    Developments between 2004 and 2006 indicate that a North European Gas Pipeline (NEGP) through the Baltic Sea, from Russia to Germany, may be realised in the coming decade. This would provide Europe with yet another opportunity to diversify its import channels of gas. It is however reasonable to assume that the NEGP also could change the strategic pattern and be a source of friction. The NEGP may rock the regional stability and reduce the potential of the new EU members to become security providers in Europe's northern dimension. It also gives increased leverage and influence to Russia, a state that has moved in an authoritarian direction under President Putin. The aim of this pilot study is to elucidate on the NEGP pipeline and Sweden's increasing dependence on Russian energy. A subsidiary aim is to outline a set of concerns that have bearing on the situation for the EU and Baltic Sea Region and that need to be further addressed. In conclusion, the NEGP will enhance Russia's direct leverage on Poland, Ukraine, and Belarus, as it will allow Russia to turn off gas supplies without affecting exports to other parts of Europe. Russia will also increase its leverage over the states that will or may be connected to the NEGP (Germany, and possibly Belgium, Denmark, the Netherlands and the UK). Even if Sweden is not embracing the NEGP, it is today highly sensitive as it imports most of its energy. It is increasingly dependent on Russian oil and is partly dependent on imports of electricity from Russia. Should the NEGP materialise and Sweden becomes connected in the future, it would likely be dependent also on natural gas. It is of paramount importance for the energy security of the connected states how the pipeline is constructed and operated. If there will be technical possibilities for Russia to tamper with the flow of gas to individual states without affecting supply to others, there are tangible threats to the importing states.

  15. Sweden and the NEGP: A Pilot Study of the North European Gas Pipeline and Sweden's Dependence on Russian Energy

    International Nuclear Information System (INIS)

    Larsson, Robert L.

    2006-06-01

    Developments between 2004 and 2006 indicate that a North European Gas Pipeline (NEGP) through the Baltic Sea, from Russia to Germany, may be realised in the coming decade. This would provide Europe with yet another opportunity to diversify its import channels of gas. It is however reasonable to assume that the NEGP also could change the strategic pattern and be a source of friction. The NEGP may rock the regional stability and reduce the potential of the new EU members to become security providers in Europe's northern dimension. It also gives increased leverage and influence to Russia, a state that has moved in an authoritarian direction under President Putin. The aim of this pilot study is to elucidate on the NEGP pipeline and Sweden's increasing dependence on Russian energy. A subsidiary aim is to outline a set of concerns that have bearing on the situation for the EU and Baltic Sea Region and that need to be further addressed. In conclusion, the NEGP will enhance Russia's direct leverage on Poland, Ukraine, and Belarus, as it will allow Russia to turn off gas supplies without affecting exports to other parts of Europe. Russia will also increase its leverage over the states that will or may be connected to the NEGP (Germany, and possibly Belgium, Denmark, the Netherlands and the UK). Even if Sweden is not embracing the NEGP, it is today highly sensitive as it imports most of its energy. It is increasingly dependent on Russian oil and is partly dependent on imports of electricity from Russia. Should the NEGP materialise and Sweden becomes connected in the future, it would likely be dependent also on natural gas. It is of paramount importance for the energy security of the connected states how the pipeline is constructed and operated. If there will be technical possibilities for Russia to tamper with the flow of gas to individual states without affecting supply to others, there are tangible threats to the importing states

  16. Northern employment

    International Nuclear Information System (INIS)

    Zavitz, J.

    1997-01-01

    Hiring practices and policies and employment opportunities that were available in the Beaufort Sea and MacKenzie Delta project for local residents and for people from southern Canada were dealt with in this chapter. Depending on the source, Northern hiring was a mere token, or a genuine and successful effort on the part of the companies to involve the native population and to share with them the benefits of the project. The fact remains that opening up job opportunities for Northerners was not easily attained, and would never have been realized without the involvement of government and community organizations. Government also played a major role in developing policies and training regimes. By the end of exploration operations, the hiring of Northern residents in the oil and gas industry had become a requirement of drilling applications. Training programs were also created to ensure that Northern residents received the means necessary to take advantage of Northern employment opportunities

  17. Residue levels of polychlorobiphenyls,. sigma. DDT, and mercury in bird species commonly preyed upon by the peregrine falcon (Falco peregrinus Tunst. ) in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Lindberg, P.; Odsjoe, T.; Reutergardh, L.

    1985-03-01

    The levels of polychlorobiphenyls (PCBs), ..sigma..DDT, and total mercury were analyzed in samples of common prey species of the peregrine falcon in two falcon territories, one in northern and one in southern Sweden. Resident and herbivorous prey species showed low residue levels, while elevated levels were found in birds feeding on animals in aquatic habitats. According to biomass, waders accounted for most of the mercury and ..sigma..DDT in the diet of the northern falcons, while the black-headed gulls had this role in southern Sweden. During the breeding season, the peregrines in northern Sweden were exposed to significantly higher levels of ..sigma..DDT and Hg than the southern peregrines. The estimated average residue levels (based on breast muscles) in a diet were in northern Sweden 0.26 ppm ..sigma..DDT, 0.47 ppm PCB and 0.20 ppm Hg wet-weight. Corresponding figures for southern Sweden were 0.17 ppm ..sigma..DDT, 0.53 ppm PCB and 0.07 ppm Hg. The organochlorine levels in a sample of peregrine eggs were higher than expected from contaminant levels in the diet. It is possible that the main accumulation of pesticides occurs on wintering grounds in western Europe for the Fennoscandian peregrines.

  18. Changes in the geographical distribution and abundance of the tick Ixodes ricinus during the past 30 years in Sweden

    Directory of Open Access Journals (Sweden)

    Jaenson Thomas GT

    2012-01-01

    Full Text Available Abstract Background Ixodes ricinus is the main vector in Europe of human-pathogenic Lyme borreliosis (LB spirochaetes, the tick-borne encephalitis virus (TBEV and other pathogens of humans and domesticated mammals. The results of a previous 1994 questionnaire, directed at people living in Central and North Sweden (Svealand and Norrland and aiming to gather information about tick exposure for humans and domestic animals, suggested that Ixodes ricinus ticks had become more widespread in Central Sweden and the southern part of North Sweden from the early 1980s to the early 1990s. To investigate whether the expansion of the tick's northern geographical range and the increasing abundance of ticks in Sweden were still occurring, in 2009 we performed a follow-up survey 16 years after the initial study. Methods A questionnaire similar to the one used in the 1994 study was published in Swedish magazines aimed at dog owners, home owners, and hunters. The questionnaire was published together with a popular science article about the tick's biology and role as a pathogen vector in Sweden. The magazines were selected to get information from people familiar with ticks and who spend time in areas where ticks might be present. Results Analyses of data from both surveys revealed that during the near 30-year period from the early 1980s to 2008, I. ricinus has expanded its distribution range northwards. In the early 1990s ticks were found in new areas along the northern coastline of the Baltic Sea, while in the 2009 study, ticks were reported for the first time from many locations in North Sweden. This included locations as far north as 66°N and places in the interior part of North Sweden. During this 16-year period the tick's range in Sweden was estimated to have increased by 9.9%. Most of the range expansion occurred in North Sweden (north of 60°N where the tick's coverage area doubled from 12.5% in the early 1990s to 26.8% in 2008. Moreover, according to the

  19. Changes in the geographical distribution and abundance of the tick Ixodes ricinus during the past 30 years in Sweden.

    Science.gov (United States)

    Jaenson, Thomas G T; Jaenson, David G E; Eisen, Lars; Petersson, Erik; Lindgren, Elisabet

    2012-01-10

    Ixodes ricinus is the main vector in Europe of human-pathogenic Lyme borreliosis (LB) spirochaetes, the tick-borne encephalitis virus (TBEV) and other pathogens of humans and domesticated mammals. The results of a previous 1994 questionnaire, directed at people living in Central and North Sweden (Svealand and Norrland) and aiming to gather information about tick exposure for humans and domestic animals, suggested that Ixodes ricinus ticks had become more widespread in Central Sweden and the southern part of North Sweden from the early 1980s to the early 1990s. To investigate whether the expansion of the tick's northern geographical range and the increasing abundance of ticks in Sweden were still occurring, in 2009 we performed a follow-up survey 16 years after the initial study. A questionnaire similar to the one used in the 1994 study was published in Swedish magazines aimed at dog owners, home owners, and hunters. The questionnaire was published together with a popular science article about the tick's biology and role as a pathogen vector in Sweden. The magazines were selected to get information from people familiar with ticks and who spend time in areas where ticks might be present. Analyses of data from both surveys revealed that during the near 30-year period from the early 1980s to 2008, I. ricinus has expanded its distribution range northwards. In the early 1990s ticks were found in new areas along the northern coastline of the Baltic Sea, while in the 2009 study, ticks were reported for the first time from many locations in North Sweden. This included locations as far north as 66°N and places in the interior part of North Sweden. During this 16-year period the tick's range in Sweden was estimated to have increased by 9.9%. Most of the range expansion occurred in North Sweden (north of 60°N) where the tick's coverage area doubled from 12.5% in the early 1990s to 26.8% in 2008. Moreover, according to the respondents, the abundance of ticks had increased

  20. Candidate gene resequencing to identify rare, pedigree-specific variants influencing healthy aging phenotypes in the long life family study

    DEFF Research Database (Denmark)

    Druley, Todd E; Wang, Lihua; Lin, Shiow J

    2016-01-01

    from six pedigrees. OBFC1 (chromosome 10) is involved in telomere maintenance, and falls within a linkage peak recently reported from an analysis of telomere length in LLFS families. Two different algorithms for single gene associations identified three genes with an enrichment of variation......BACKGROUND: The Long Life Family Study (LLFS) is an international study to identify the genetic components of various healthy aging phenotypes. We hypothesized that pedigree-specific rare variants at longevity-associated genes could have a similar functional impact on healthy phenotypes. METHODS......: We performed custom hybridization capture sequencing to identify the functional variants in 464 candidate genes for longevity or the major diseases of aging in 615 pedigrees (4,953 individuals) from the LLFS, using a multiplexed, custom hybridization capture. Variants were analyzed individually...

  1. Chlorine activation and ozone destruction in the northern lowermost stratosphere

    NARCIS (Netherlands)

    Lelieveld, J; Bregman, A; Scheeren, HA; Strom, J; Carslaw, KS; Fischer, H; Siegmund, PC; Arnold, F

    1999-01-01

    We report aircraft measurements from the Stratosphere-Troposphere Experiments by Aircraft Measurements (STREAM) II campaign, performed during February 1995 from Kiruna, northern Sweden, near 67 degrees N latitude. We have measured trace species, e.g., O-3, nitrogen compounds, HCl, hydrocarbons, CO,

  2. [Clinical features of a Chinese pedigree with Waardenburg syndrome type 2].

    Science.gov (United States)

    Yang, Shu-zhi; Yuan, Hui-jun; Bai, Lin-na; Cao, Ju-yang; Xu, Ye; Shen, Wei-dong; Ji, Fei; Yang, Wei-yan

    2005-10-12

    To investigate detailed clinical features of a Chinese pedigree with Waardenburg syndrome type 2. Members of this pedigree were interviewed to identify personal or family medical histories of hearing loss, the use of aminoglycosides, and other clinical abnormalities by filling questionnaire. The audiological and other clinical evaluations of the proband and other members of this family were conducted, including pure-tone audiometry, immittance and auditory brain-stem response and ophthalmological, dermatologic, hair, temporal bone CT examinations. This family is categorized as Waardenburg syndrome type 2 according to its clinical features. It's an autosomal dominant disorder with incomplete penetrance. The clinical features varied greatly among family members and characterized by sensorineural hearing loss, heterochromia irides, freckle on the face and premature gray hair. Hearing loss can be unilateral or bilateral, congenital or late onset in this family. This Chinese family has some unique clinical features comparing with the international diagnostic criteria for Waardenburg syndrome. This study may provide some evidences to amend the diagnostic criteria for Waardenburg syndrome in Chinese population.

  3. Efficient Maximum Likelihood Estimation for Pedigree Data with the Sum-Product Algorithm.

    Science.gov (United States)

    Engelhardt, Alexander; Rieger, Anna; Tresch, Achim; Mansmann, Ulrich

    2016-01-01

    We analyze data sets consisting of pedigrees with age at onset of colorectal cancer (CRC) as phenotype. The occurrence of familial clusters of CRC suggests the existence of a latent, inheritable risk factor. We aimed to compute the probability of a family possessing this risk factor as well as the hazard rate increase for these risk factor carriers. Due to the inheritability of this risk factor, the estimation necessitates a costly marginalization of the likelihood. We propose an improved EM algorithm by applying factor graphs and the sum-product algorithm in the E-step. This reduces the computational complexity from exponential to linear in the number of family members. Our algorithm is as precise as a direct likelihood maximization in a simulation study and a real family study on CRC risk. For 250 simulated families of size 19 and 21, the runtime of our algorithm is faster by a factor of 4 and 29, respectively. On the largest family (23 members) in the real data, our algorithm is 6 times faster. We introduce a flexible and runtime-efficient tool for statistical inference in biomedical event data with latent variables that opens the door for advanced analyses of pedigree data. © 2017 S. Karger AG, Basel.

  4. Prediction of genetic values of quantitative traits in plant breeding using pedigree and molecular markers.

    Science.gov (United States)

    Crossa, José; Campos, Gustavo de Los; Pérez, Paulino; Gianola, Daniel; Burgueño, Juan; Araus, José Luis; Makumbi, Dan; Singh, Ravi P; Dreisigacker, Susanne; Yan, Jianbing; Arief, Vivi; Banziger, Marianne; Braun, Hans-Joachim

    2010-10-01

    The availability of dense molecular markers has made possible the use of genomic selection (GS) for plant breeding. However, the evaluation of models for GS in real plant populations is very limited. This article evaluates the performance of parametric and semiparametric models for GS using wheat (Triticum aestivum L.) and maize (Zea mays) data in which different traits were measured in several environmental conditions. The findings, based on extensive cross-validations, indicate that models including marker information had higher predictive ability than pedigree-based models. In the wheat data set, and relative to a pedigree model, gains in predictive ability due to inclusion of markers ranged from 7.7 to 35.7%. Correlation between observed and predictive values in the maize data set achieved values up to 0.79. Estimates of marker effects were different across environmental conditions, indicating that genotype × environment interaction is an important component of genetic variability. These results indicate that GS in plant breeding can be an effective strategy for selecting among lines whose phenotypes have yet to be observed.

  5. Pedigree analysis on the population of Gir cattle in Northeast Brazil

    Directory of Open Access Journals (Sweden)

    Aracele Prates de Oliveira

    2012-05-01

    Full Text Available The objective of this study was to characterize the population genetic structure of the Gir breed in the Northeast of Brazil. The data used in this study were taken from pedigree information of 8,897 Gir animals between 1957 and 2007, obtained from the Brazilian Zebu Breeders Association (ABCZ. The program ENDOG was used to estimate the parameters based on the probability gene origin. From the amount of the studied animals, 67.22%, 18.41% and 3.15% had complete pedigree only on the first, second and third parentage, respectively. The number of ancestors that contributed for the reference population was 2,755, of which only 171 explain the 50% genetic variability of the population. The actual number of founder herds was 168 and the effective number of founder herds was 22.3. The number of sire supplier herds was 22.16, 8.66 and 5.36 for fathers, grandfathers and great-grandfathers, respectively. The average coefficient of relatedness was estimated at 0.22%; the highest individual coefficient was 1.49%. The little variability of the current population is a result of the small number of effective founders and ancestors indicating the population evolved from a narrow genetic base.

  6. The value of extended pedigrees for next-generation analysis of complex disease in the rhesus macaque.

    Science.gov (United States)

    Vinson, Amanda; Prongay, Kamm; Ferguson, Betsy

    2013-01-01

    Complex diseases (e.g., cardiovascular disease and type 2 diabetes, among many others) pose the biggest threat to human health worldwide and are among the most challenging to investigate. Susceptibility to complex disease may be caused by multiple genetic variants (GVs) and their interaction, by environmental factors, and by interaction between GVs and environment, and large study cohorts with substantial analytical power are typically required to elucidate these individual contributions. Here, we discuss the advantages of both power and feasibility afforded by the use of extended pedigrees of rhesus macaques (Macaca mulatta) for genetic studies of complex human disease based on next-generation sequence data. We present these advantages in the context of previous research conducted in rhesus macaques for several representative complex diseases. We also describe a single, multigeneration pedigree of Indian-origin rhesus macaques and a sample biobank we have developed for genetic analysis of complex disease, including power of this pedigree to detect causal GVs using either genetic linkage or association methods in a variance decomposition approach. Finally, we summarize findings of significant heritability for a number of quantitative traits that demonstrate that genetic contributions to risk factors for complex disease can be detected and measured in this pedigree. We conclude that the development and application of an extended pedigree to analysis of complex disease traits in the rhesus macaque have shown promising early success and that genome-wide genetic and higher order -omics studies in this pedigree are likely to yield useful insights into the architecture of complex human disease.

  7. Development of nuclear power in Sweden

    International Nuclear Information System (INIS)

    Sokolowski, E.

    1994-01-01

    The history and development of nuclear energetics in Sweden has been described. Up to now 12 units (9 BWR and 3 PWR nuclear reactors) with total 70 TWh electric power is being working in Sweden. If the same power will be installed as a coal-fired units the emissions of 65 million tons of CO 2 , 240,000 tons of SO 2 and 140 tons of NO x would be expected. 1 tab

  8. Radon in dwellings in Sweden

    International Nuclear Information System (INIS)

    Swedjemark, G.A.

    1978-04-01

    Studies on the specific activities in building materials, the γ-radiation levels in dwellings, the concentrations of radon and daughters in the air indoors and the concentration of radon in tap water are in progress in Sweden. On basis of these investigations and of the investigation of Hultqvist from the beginning of the 1950s, an attempt has been made to show how the radiation doses in dwellings have changed or may be changed by human activities and what these changes imply in terms of collective dose. The annual collective absorbed dose in the basal cells of the critical bronchial region have increased from 11 . 10 3 manGy for the occupants of dwellings existing in 1950 to 25 . 10 3 manGy for dwellings existing in 1975. If the building of houses continues as at present it can be estimated that the annual collective dose will be between 25 and 31 . 10 3 manGy for the dwellings of 1985. (author)

  9. Ageing management requirements in Sweden

    International Nuclear Information System (INIS)

    Gott, K.

    2007-01-01

    Since the adoption of the 1997 act of parliament concerning the abolishment of nuclear power in Sweden plant lives are no longer limited until 2010 as they were following the referendum in 1980. The Swedish Nuclear Power Inspectorate (SKI) has therefore in its most recent general regulations from 2004 introduced requirements for plants to develop ageing management programmes which should have been in place by the end of 2005. An ageing management programme for a nuclear power plant can be viewed as a high level coordinated programme consisting of several other programmes including maintenance and inspection programmes, and as such it should be an integrated part of the quality assurance system of the plant. The goals of the programme are to ensure that there is long term management of ageing and avoidance of the unexpected. For the Swedish regulator the safety aspects and not the economic aspects of ageing management are of primary importance. But there are clear advantages to utilities if large surprises which result in unplanned outages can be avoided. (author)

  10. Mapping key economic indicators of onshore wind energy in Sweden by using a geospatial methodology

    International Nuclear Information System (INIS)

    Siyal, Shahid Hussain; Mentis, Dimitris; Howells, Mark

    2016-01-01

    Highlights: • We spatially quantified and visualized the economic indicators of onshore wind energy in Sweden. • Possible land use constraints to wind energy were taken into account. • Economic indicators were estimated on the basis of two wind turbines. • We used a GIS-based methodology for this analysis and found it very useful. • Results suggest that Sweden holds economic feasible wind energy resource, specially in the southern and central regions. - Abstract: Due to modern advancements in renewable energy systems and increasing prices of fossil fuels wind energy is getting a lot of attention all over the world. In this regard, Sweden also fixed motivated targets to get energy supply from local renewable energy resources. So, local wind power could help the country in achieving the targets. In this study, economic indicators of wind energy were spatially estimated for Sweden by using ArcGIS tool. In order to do this, as input data one-year high resolution modeled annual average wind data was processed by means of Rayleigh distribution, wind turbine power curve, land use constraints, technical constraints and economic parameters. Based on the input data, it was concluded that Sweden possesses economically feasible wind energy resource. The results of the study indicate that southern and central regions could produce economically viable wind electricity in all aspects as compared to the northern region of the country. Lastly, it was recommended to speed up wind energy penetration in Sweden, communal awareness and acceptance regarding the resource should be increased to avoid possible misunderstanding. Additionally, the capability of the national electric grid should be enhanced to take up the large scale unpredictable wind energy resource.

  11. [Linkage analysis of susceptibility loci in 2 target chromosomes in pedigrees with paranoid schizophrenia and undifferentiated schizophrenia].

    Science.gov (United States)

    Zeng, Li-ping; Hu, Zheng-mao; Mu, Li-li; Mei, Gui-sen; Lu, Xiu-ling; Zheng, Yong-jun; Li, Pei-jian; Zhang, Ying-xue; Pan, Qian; Long, Zhi-gao; Dai, He-ping; Zhang, Zhuo-hua; Xia, Jia-hui; Zhao, Jing-ping; Xia, Kun

    2011-06-01

    To investigate the relationship of susceptibility loci in chromosomes 1q21-25 and 6p21-25 and schizophrenia subtypes in Chinese population. A genomic scan and parametric and non-parametric analyses were performed on 242 individuals from 36 schizophrenia pedigrees, including 19 paranoid schizophrenia and 17 undifferentiated schizophrenia pedigrees, from Henan province of China using 5 microsatellite markers in the chromosome region 1q21-25 and 8 microsatellite markers in the chromosome region 6p21-25, which were the candidates of previous studies. All affected subjects were diagnosed and typed according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revised (DSM-IV-TR; American Psychiatric Association, 2000). All subjects signed informed consent. In chromosome 1, parametric analysis under the dominant inheritance mode of all 36 pedigrees showed that the maximum multi-point heterogeneity Log of odds score method (HLOD) score was 1.33 (α = 0.38). The non-parametric analysis and the single point and multi-point nonparametric linkage (NPL) scores suggested linkage at D1S484, D1S2878, and D1S196. In the 19 paranoid schizophrenias pedigrees, linkage was not observed for any of the 5 markers. In the 17 undifferentiated schizophrenia pedigrees, the multi-point NPL score was 1.60 (P= 0.0367) at D1S484. The single point NPL score was 1.95(P= 0.0145) and the multi-point NPL score was 2.39 (P= 0.0041) at D1S2878. Additionally, the multi-point NPL score was 1.74 (P= 0.0255) at D1S196. These same three loci showed suggestive linkage during the integrative analysis of all 36 pedigrees. In chromosome 6, parametric linkage analysis under the dominant and recessive inheritance and the non-parametric linkage analysis of all 36 pedigrees and the 17 undifferentiated schizophrenia pedigrees, linkage was not observed for any of the 8 markers. In the 19 paranoid schizophrenias pedigrees, parametric analysis showed that under recessive

  12. Electricity supply in Sweden 1983

    International Nuclear Information System (INIS)

    1984-01-01

    The year 1983 was characterized by a continued decrease in oil consumption and an increase in electricity consumption. Totally the supply of fuels decreased from 278TWh to 264 TWh in 1983. The electricity supply increased from 99.9 TWh in 1982 to 110.8 TWh in 1983. The consumers total energy use decreased from 358 TWh in 1982 to 355 TWh in 1983. Electricity consumption excluding transmission losses increased from 91,4 TWh in 1982 to 101.1TWh in 1983. The increase was due to electric space heating disconnectable electric boilers and to industry. At the end of 1983 the electric heating subscriptions are estimated to corresponds to 45 percent of all one-family houses. Hydropower accounted for 54 percent and nucler power accounted for 34 percent of the total supply of electricity in 1983. The highest hourly load during 1983 amounted to 20862 MW. The lowest load during 1983 amounted to 5185 MW. Ten nuclear power units were in commercial operation during the year. The energy availability figures were as follows: Barsebaeck 1 85 percent, Barsebaeck 2 82 percent, Forsmark 1 84 percent, Forsmark 2 88 percent, Oskarshamn 1 87 percent, Oskarshamn 2 83 percent, Ringhals 1 59 percent and Ringhals 2 68 percent. The production of electricity from conventional thermal power stations was only 4.0 TWh. Back pressure power in industry contributed 2.5 TWh of this figure and combined power and district heating stations 1.3 TWh. Two coal fired combined power and district heating plants were added and sevearl combined power and district heating plants have been rebuilt to be coal fired. The high voltage power grid system permits joint operation by all the power companies in the country, and the major power companies utilize the network for exchanging surplus power with other power companies. An account of the public debate on energy in Sweden during 1983 is also given.(L.E.)

  13. Linkage of familial Alzheimer disease to chromosome 14 in two large early-onset pedigrees: effects of marker allele frequencies on lod scores.

    Science.gov (United States)

    Nechiporuk, A; Fain, P; Kort, E; Nee, L E; Frommelt, E; Polinsky, R J; Korenberg, J R; Pulst, S M

    1993-05-01

    Alzheimer disease (AD) is a devastating neurodegenerative disease leading to global dementia. In addition to sporadic forms of AD, familial forms (FAD) have been recognized. Mutations in the amyloid precursor protein (APP) gene on chromosome (CHR) 21 have been shown to cause early-onset AD in a small number of pedigrees. Recently, linkage to markers on CHR 14 has been established in several early-onset FAD pedigrees. We now report lod scores for CHR 14 markers in two large early-onset FAD pedigrees. Pairwise linkage analysis suggested that in these pedigrees the mutation is tightly linked to the loci D14S43 and D14S53. However, assumptions regarding marker allele frequencies had a major and often unpredictable effect on calculated lod scores. Therefore, caution needs to be exercised when single pedigrees are analyzed with marker allele frequencies determined from the literature or from a pool of spouses.

  14. Homologous series of induced early mutants in Indica rice. Pt.3: The relationship between the induction of homologous series of early mutants and its different pedigree

    International Nuclear Information System (INIS)

    Chen Xiulan; Yang Hefeng; He Zhentian; Han Yuepeng; Liu Xueyu

    2002-01-01

    The percentage of homologous series of early mutants (PHSEM) induced by irradiation was closely related to its pedigree. This study showed that PHSEM for varieties with the same pedigree were similar, and there were three different level of dominance (high, low and normal) in the homologous series induced from different pedigree. The PHSEM for varieties derived form distant-relative-parents were higher than that derived from close-relative-parents. There was the dominance pedigree for the induction of homologous series of early mutants. IR8(Peta x DGWG), IR127 (Cpslo x Sigadis) and IR24 (IR8 x IR127) were dominant pedigree, and varieties derived from them could be easily induced the homologous series of early mutants

  15. CO2 storage in Sweden

    International Nuclear Information System (INIS)

    Ekstroem, Clas; Andersson, Annika; Kling, Aasa; Bernstone, Christian; Carlsson, Anders; Liljemark, Stefan; Wall, Caroline; Erstedt, Thomas; Lindroth, Maria; Tengborg, Per; Edstroem, Mikael

    2004-07-01

    This study considers options, that could be feasible for Sweden, to transport and geologically store CO 2 , providing that technology for electricity production with CO 2 capture will be available in the future and also acceptable from cost- and reliability point of view. As a starting point, it is assumed that a new 600-1000 MW power plant, fired with coal or natural gas, will be constructed with CO 2 capture and localised to the Stockholm, Malmoe or Goeteborg areas. Of vital importance for storage of carbon dioxide in a reservoir is the possibility to monitor its distribution, i.e. its migration within the reservoir. It has been shown in the SACS-project that the distribution of carbon dioxide within the reservoir can be monitored successfully, mainly by seismic methods. Suitable geologic conditions and a large storage potential seems to exist mainly in South West Scania, where additional knowledge on geology/hydrogeology has been obtained since the year 2000 in connection to geothermal energy projects, and in the Eastern part of Denmark, bordering on South West Scania. Storage of carbon dioxide from the Stockholm area should not be excluded, but more studies are needed to clarify the storage options within this area. The possibilities to use CO 2 for enhanced oil recovery, EOR, in i.a. the North Sea should be investigated, in order to receive incomes from the CO 2 and shared costs for infrastructure, and by this also make the CO 2 regarded as a trading commodity, and thereby achieving a more favourable position concerning acceptance, legal issues and regulations. The dimensions of CO 2 -pipelines should be similar to those for natural natural gas, although regarding some aspects they have different design and construction prerequisites. To obtain cost efficiency, the transport distances should be kept short, and possibilities for co-ordinated networks with short distribution pipelines connected to common main pipelines, should be searched for. Also, synergies

  16. Genomic and pedigree-based prediction for leaf, stem, and stripe rust resistance in wheat.

    Science.gov (United States)

    Juliana, Philomin; Singh, Ravi P; Singh, Pawan K; Crossa, Jose; Huerta-Espino, Julio; Lan, Caixia; Bhavani, Sridhar; Rutkoski, Jessica E; Poland, Jesse A; Bergstrom, Gary C; Sorrells, Mark E

    2017-07-01

    Genomic prediction for seedling and adult plant resistance to wheat rusts was compared to prediction using few markers as fixed effects in a least-squares approach and pedigree-based prediction. The unceasing plant-pathogen arms race and ephemeral nature of some rust resistance genes have been challenging for wheat (Triticum aestivum L.) breeding programs and farmers. Hence, it is important to devise strategies for effective evaluation and exploitation of quantitative rust resistance. One promising approach that could accelerate gain from selection for rust resistance is 'genomic selection' which utilizes dense genome-wide markers to estimate the breeding values (BVs) for quantitative traits. Our objective was to compare three genomic prediction models including genomic best linear unbiased prediction (GBLUP), GBLUP A that was GBLUP with selected loci as fixed effects and reproducing kernel Hilbert spaces-markers (RKHS-M) with least-squares (LS) approach, RKHS-pedigree (RKHS-P), and RKHS markers and pedigree (RKHS-MP) to determine the BVs for seedling and/or adult plant resistance (APR) to leaf rust (LR), stem rust (SR), and stripe rust (YR). The 333 lines in the 45th IBWSN and the 313 lines in the 46th IBWSN were genotyped using genotyping-by-sequencing and phenotyped in replicated trials. The mean prediction accuracies ranged from 0.31-0.74 for LR seedling, 0.12-0.56 for LR APR, 0.31-0.65 for SR APR, 0.70-0.78 for YR seedling, and 0.34-0.71 for YR APR. For most datasets, the RKHS-MP model gave the highest accuracies, while LS gave the lowest. GBLUP, GBLUP A, RKHS-M, and RKHS-P models gave similar accuracies. Using genome-wide marker-based models resulted in an average of 42% increase in accuracy over LS. We conclude that GS is a promising approach for improvement of quantitative rust resistance and can be implemented in the breeding pipeline.

  17. A likelihood ratio-based method to predict exact pedigrees for complex families from next-generation sequencing data.

    Science.gov (United States)

    Heinrich, Verena; Kamphans, Tom; Mundlos, Stefan; Robinson, Peter N; Krawitz, Peter M

    2017-01-01

    Next generation sequencing technology considerably changed the way we screen for pathogenic mutations in rare Mendelian disorders. However, the identification of the disease-causing mutation amongst thousands of variants of partly unknown relevance is still challenging and efficient techniques that reduce the genomic search space play a decisive role. Often segregation- or linkage analysis are used to prioritize candidates, however, these approaches require correct information about the degree of relationship among the sequenced samples. For quality assurance an automated control of pedigree structures and sample assignment is therefore highly desirable in order to detect label mix-ups that might otherwise corrupt downstream analysis. We developed an algorithm based on likelihood ratios that discriminates between different classes of relationship for an arbitrary number of genotyped samples. By identifying the most likely class we are able to reconstruct entire pedigrees iteratively, even for highly consanguineous families. We tested our approach on exome data of different sequencing studies and achieved high precision for all pedigree predictions. By analyzing the precision for varying degrees of relatedness or inbreeding we could show that a prediction is robust down to magnitudes of a few hundred loci. A java standalone application that computes the relationships between multiple samples as well as a Rscript that visualizes the pedigree information is available for download as well as a web service at www.gene-talk.de CONTACT: heinrich@molgen.mpg.deSupplementary information: Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press.

  18. Compatibility of pedigree-based and marker-based relationship matrices for single-step genetic evaluation

    DEFF Research Database (Denmark)

    Christensen, Ole Fredslund

    2012-01-01

    Single-step methods for genomic prediction have recently become popular because they are conceptually simple and in practice such a method can completely replace a pedigree-based method for routine genetic evaluation. An issue with single-step methods is compatibility between the marker-based rel...

  19. Improving uncertainty evaluation of process models by using pedigree analysis. A case study on CO2 capture with monoethanolamine

    NARCIS (Netherlands)

    van der Spek, Mijndert; Ramirez, Andrea; Faaij, André

    2016-01-01

    This article aims to improve uncertainty evaluation of process models by combining a quantitative uncertainty evaluation method (data validation) with a qualitative uncertainty evaluation method (pedigree analysis). The approach is tested on a case study of monoethanolamine based postcombustion CO2

  20. HLA haplotype map of river valley populations with hemochromatosis traced through five centuries in Central Sweden.

    Science.gov (United States)

    Olsson, K Sigvard; Ritter, Bernd; Hansson, Norbeth; Chowdhury, Ruma R

    2008-07-01

    The hemochromatosis mutation, C282Y of the HFE gene, seems to have originated from a single event which once occurred in a person living in the north west of Europe carrying human leukocyte antigen (HLA)-A3-B7. In descendants of this ancestor also other haplotypes appear probably caused by local recombinations and founder effects. The background of these associations is unknown. Isolated river valley populations may be fruitful for the mapping of genetic disorders such as hemochromatosis. In this study, we try to test this hypothesis in a study from central Sweden where the haplotyope A1-B8 was common. HLA haplotypes and HFE mutations were studied in hemochromatosis patients with present or past parental origin in a sparsely populated (1/km(2)) rural district (n = 8366 in the year of 2005), in central Sweden. Pedigrees were constructed from the Swedish church book registry. Extended haplotypes were studied to evaluate origin of recombinations. There were 87 original probands, 36 females and 51 males identified during 30 yr, of whom 86% carried C282Y/C282Y and 14% C282Y/H63D. Of 32 different HLA haplotypes A1-B8 was the most common (34%), followed by A3-B7 (16%), both in strong linkage disequilibrium with controls, (P females. River valley populations may contain HLA haplotypes reflecting their demographic history. This study has demonstrated that the resistance against recombinations between HLA-A and HFE make HLA haplotypes excellent markers for population movements. Founder effects and genetic drift from bottleneck populations (surviving the plague?) may explain the commonness of the mutation in central Scandinavia. The intergenerational time difference >30 yr was greater than expected and means that the age of the original mutation may be underestimated.

  1. Rules for resolving Mendelian inconsistencies in nuclear pedigrees typed for two-allele markers.

    Directory of Open Access Journals (Sweden)

    Sajjad Ahmad Khan

    Full Text Available Gene-mapping studies, regularly, rely on examination for Mendelian transmission of marker alleles in a pedigree as a way of screening for genotyping errors and mutations. For analysis of family data sets, it is, usually, necessary to resolve or remove the genotyping errors prior to consideration. At the Center of Inherited Disease Research (CIDR, to deal with their large-scale data flow, they formalized their data cleaning approach in a set of rules based on PedCheck output. We scrutinize via carefully designed simulations that how well CIDR's data cleaning rules work in practice. We found that genotype errors in siblings are detected more often than in parents for less polymorphic SNPs and vice versa for more polymorphic SNPs. Through computer simulations, we conclude that some of the CIDR's rules work poorly in some circumstances, and we suggest a set of modified data cleaning rules that may work better than CIDR's rules.

  2. [Clinical classification and genetic mutation study of two pedigrees with type II Waardenburg syndrome].

    Science.gov (United States)

    Chen, Yong; Yang, Fuwei; Zheng, Hexin; Zhu, Ganghua; Hu, Peng; Wu, Weijing

    2015-12-01

    To explore the molecular etiology of two pedigrees affected with type II Waardenburg syndrome (WS2) and to provide genetic diagnosis and counseling. Blood samples were collected from the proband and his family members. Following extraction of genomic DNA, the coding sequences of PAX3, MITF, SOX10 and SNAI2 genes were amplified with PCR and subjected to DNA sequencing to detect potential mutations. A heterozygous deletional mutation c.649_651delAGA in exon 7 of the MITF gene has been identified in all patients from the first family, while no mutation was found in the other WS2 related genes including PAX3, MITF, SOX10 and SNAI2. The heterozygous deletion mutation c.649_651delAGA in exon 7 of the MITF gene probably underlies the disease in the first family. It is expected that other genes may also underlie WS2.

  3. Phenotypic variation in a large Swedish pedigree due to SNCA duplication and triplication

    DEFF Research Database (Denmark)

    Fuchs, J; Nilsson, C; Kachergus, J

    2007-01-01

    complex. The genetic basis for familial parkinsonism is an SNCA-MMRN11 multiplication, but whereas SNCA-MMRN1 duplication in the Swedish proband (Branch J) leads to late-onset autonomic dysfunction and parkinsonism, SNCA-MMRN1 triplication in the Swedish American family (Branch I) leads to early......BACKGROUND: The "Lister family complex," an extensive Swedish family with autosomal dominant Parkinson disease, was first described by Henry Mjönes in 1949. On the basis of clinical, molecular, and genealogic findings on a Swedish and an American family branch, we provide genetic evidence...... that explains the parkinsonism in this extended pedigree. METHODS: Clinical methods included a detailed neurologic exam of the proband of the Swedish family branch, MRI, and ([123]I)-beta-CIT SPECT imaging. Genomic analysis included alpha-synuclein sequencing, SNCA real-time PCR dosage, chromosome 4q21...

  4. Cell organisation in the colonic crypt: a theoretical comparison of the pedigree and niche concepts.

    Directory of Open Access Journals (Sweden)

    Richard C van der Wath

    Full Text Available The intestinal mucosa is a monolayer of rapidly self-renewing epithelial cells which is not only responsible for absorption of water and nutrients into the bloodstream but also acts as a protective barrier against harmful microbes entering the body. New functional epithelial cells are produced from stem cells, and their proliferating progeny. These stem cells are found within millions of crypts (tubular pits spaced along the intestinal tract. The entire intestinal epithelium is replaced every 2-3 days in mice (3-5 days in humans and hence cell production, differentiation, migration and turnover need to be tightly regulated. Malfunctions in this regulation are strongly linked to inflammatory bowel diseases and to the formation of adenomas and ultimately cancerous tumours. Despite a great deal of biological experimentation and observation, precisely how colonic crypts are regulated to produce mature colonocytes remains unclear. To assist in understanding how cell organisation in crypts is achieved, two very different conceptual models of cell behaviour are developed here, referred to as the 'pedigree' and the 'niche' models. The pedigree model proposes that crypt cells are largely preprogrammed and receive minimal prompting from the environment as they move through a routine of cell differentiation and proliferation to become mature colonocytes. The niche model proposes that crypt cells are primarily influenced by the local microenvironments along the crypt, and that predetermined cell behaviour plays a negligible role in their development. In this paper we present a computational model of colonic crypts in the mouse, which enables a comparison of the quality and controllability of mature coloncyte production by crypts operating under these two contrasting conceptual models of crypt regulation.

  5. Rooster semen cryopreservation: effect of pedigree line and male age on postthaw sperm function.

    Science.gov (United States)

    Long, J A; Bongalhardo, D C; Pelaéz, J; Saxena, S; Settar, P; O'Sullivan, N P; Fulton, J E

    2010-05-01

    The fertility rates of cryopreserved poultry semen are highly variable and not reliable for use in preservation of commercial genetic stocks. Our objective was to evaluate the cryosurvival of semen from 8 pedigreed layer lines at 2 different ages: the onset and end of commercial production. Semen from 160 roosters (20/line) was frozen individually with 11% glycerol at 6 and 12 mo of age. Glycerol was removed from thawed semen by Accudenz gradient centrifugation. The viability of thawed sperm from each male was determined using fluorescent live-dead staining and flow cytometry; sperm velocity parameters were measured using computerized motion analysis. The fertilizing ability of thawed sperm was evaluated in vitro by assessing hydrolysis of the inner perivitelline membrane. The postthaw function of sperm from the elite lines varied widely, despite the fact that fresh semen from all of these lines typically yielded high fertility rates. The percentage of thawed sperm with intact plasma membranes ranged from 27.8 + or - 2.1 to 49.6 + or - 1.9 and varied among lines and between age groups. Thawed sperm from 2 lines consistently demonstrated the highest and lowest motility parameters, whereas the velocity parameters of the remaining 6 lines varied widely. The mean number of hydrolysis points per square millimeter of inner perivitelline membrane ranged from 12.5 + or - 4.1 (line 2) to 103.3 + or - 30.2 (line 6). Age effects were observed for 4 out of 8 lines; however, improved postthaw sperm function at 12 mo of age was not consistent for all 3 assays. These results demonstrate variability among pedigreed lines in withstanding glycerol-based semen cryopreservation and provide a model for delineating genotypic and phenotypic factors affecting sperm cryosurvival.

  6. Energy in Sweden. Facts and figures 2004

    International Nuclear Information System (INIS)

    2004-12-01

    Energy in Sweden 2004: Facts and Figures contains the tabular data for most of the diagrams in the main publication. These data consist primarily of the results of the Agency's processing of basic data from Statistics Sweden. Facts and Figures is available at www.stem.se in pdf- and excel file formats. Since the year 2001 statistics for the period 1983-1998 are revised compared to data for previous editions. With effect from the 2001 edition, statistics are of preliminary character for the two preceding years. Breakdowns into certain types of fuels vary somewhat depending on whether preliminary or final data has been used. Further information about the statistics can be found in Energy in Sweden, chapter 8 Energy Facts.

  7. Health and social inequities in Sweden

    DEFF Research Database (Denmark)

    Diderichsen, Finn

    1990-01-01

    Sweden is one of Europe's most egalitarian countries. The social inequities in living conditions have been gradually reduced to a level that is more equal than in most countries in Europe. Even if general health development has been positive during recent years, data reviewed here indicate...... that there may be adverse effects for some groups which may increase inequities. This article presents results on inequities in health from the Public Health Report of Sweden 1987 and discusses causal mechanisms and implications for health policy....

  8. Iodine (I-129 and I-127) in aerosols from northern Europe

    DEFF Research Database (Denmark)

    Englund, E.; Aldahan, A.; Hou, Xiaolin

    2010-01-01

    Huge amount of 129I has been emitted to the environment during the last decades from a variety of anthropogenic nuclear activities. Aerosols represent a carrier of iodine in the atmosphere in addition to gaseous forms for which data are lacking in Sweden. In this study the first time series...... of iodine isotopes (129I and 127I) in aerosols covering the period of 1983 to 2008 from two sites in Sweden are presented. The results show that both 129I and 127I concentrations are considerably higher in southern compared to northern Sweden. Furthermore there is a significant difference in the relative...

  9. A novel Salmonella serovar isolated from Peregrine Falcon (Falco peregrinus nestlings in Sweden: Salmonella enterica enterica serovar Pajala (Salmonella Pajala

    Directory of Open Access Journals (Sweden)

    Jorge Hernández

    2012-08-01

    Full Text Available A novel Salmonella serovar was isolated from Peregrine falcon (Falco peregrinus nestlings in northern Sweden in 2006. Three isolates of the same clone was retrieved from three falcon siblings and characterized as Salmonella enterica sub-species enterica: O-phase 13, 23:-: e, n, z 15 and the H-phase was not present. We propose the geographical name Salmonella enterica, sub-species enterica serovar Pajala to this novel Salmonella.

  10. Determination of maternal pedigree and ewe-lamb spatial relationships by application of Bluetooth technology in extensive farming systems.

    Science.gov (United States)

    Sohi, R; Trompf, J; Marriott, H; Bervan, A; Godoy, B I; Weerasinghe, M; Desai, A; Jois, M

    2017-11-01

    The objectives of this study were to validate the application of Bluetooth technology to determine maternal pedigree and to determine ewe-lamb spatial relationships in extensive farming systems. A total of 35 first-cross Merino ewes (Merino × Border Leicester and East Friesian) and 23 of their lambs aged 1 to 3 wk were fitted with activity monitors equipped with Bluetooth (BT) technology (ActiGraph wGT3X-BT) by means of halters and collars, respectively. The BT devices on lambs were programmed to receive wireless signals once every minute from nearby BT units on ewes, which were programmed as beacons sending BT signals 4 times every second. Ewes and lambs fitted with sensors were dispatched into the paddocks, and after 10 d, the sensor units were retrieved and the BT signals received by lambs were downloaded using the ActiGraph software. The maternal pedigree of the lambs was determined as the ewe from which the lamb received the most BT signals. The distance between the lamb receiving the signal and the ewe sending the signal was estimated from the strength of BT signal received. The pedigree determined by BT was compared with the pedigree determined by DNA profiling and verification. The results showed that the accuracy of maternal pedigree determined by BT signals reached 100% within the first 15 min of returning animals to pasture of ewes and lambs fitted with sensors. Maternal signals (counts/d) received by 1-, 2-, and 3-wk-old lambs were 617 ± 102, 603 ± 54, and 498 ± 36, respectively, and the corresponding nonmaternal signals received were 140 ± 27, 106 ± 30, and 155 ± 39, respectively. Maternal signals received during the dark period were significantly higher than the maternal signals received during the light period ( wireless networking is a fast and reliable method for the determination of maternal pedigree of lambs in extensive farming systems. In addition, wireless BT technology is also useful in determining mother-offspring spatial

  11. Introducing Micro-finance in Sweden

    DEFF Research Database (Denmark)

    Barinaga, Ester

    2013-01-01

    The case describes the first year of efforts to introduce microfinance as a tool to work with vulnerable groups in Sweden, more particularly ex-convicts, former drug-addicts and longterm unemployed women of immigrant background. The teaching objective is to discuss whether micro-finance can be seen...

  12. Status and use of PSA in Sweden

    International Nuclear Information System (INIS)

    Knochenhauer, M.

    1996-05-01

    The performance and use of PSA:s in Sweden goes back about two decades. During all of this time, the field of PSA has been developing intensively, both internationally and within Sweden. The latest years have been characterised by an increased use of PSA models and results, and by major extensions of existing PSA models. The aim of this document is to describe PSA in Sweden with respect to development, scope and maturity, as well as to the contents of the analyses and the use of results. PSA activities will be described from the point of view of both the authorities and the utilities. The report gives an overview of the development within the area of PSA in Sweden both its history and current trends. The aim has been to include a reasonable amount of detail, both on the methods and results in PSA:s performed and on the numerous supporting research programs dealing with various aspects of PSA. 39 refs 39 refs

  13. Status and use of PSA in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Knochenhauer, M

    1996-05-01

    The performance and use of PSA:s in Sweden goes back about two decades. During all of this time, the field of PSA has been developing intensively, both internationally and within Sweden. The latest years have been characterised by an increased use of PSA models and results, and by major extensions of existing PSA models. The aim of this document is to describe PSA in Sweden with respect to development, scope and maturity, as well as to the contents of the analyses and the use of results. PSA activities will be described from the point of view of both the authorities and the utilities. The report gives an overview of the development within the area of PSA in Sweden both its history and current trends. The aim has been to include a reasonable amount of detail, both on the methods and results in PSA:s performed and on the numerous supporting research programs dealing with various aspects of PSA. 39 refs 39 refs.

  14. Energy in Sweden. Facts and figures 1999

    International Nuclear Information System (INIS)

    1999-11-01

    This supplement contains the tabular data of most of the diagrams in the main publication (Energy in Sweden 1999, STEM-ET-82-1999). The figures are based on preliminary statistics, and there may be minor differences between similar data in different sections or tables etc. All table headings and notes are given in both Swedish and English

  15. Disturbed security in Norway and Sweden

    Directory of Open Access Journals (Sweden)

    Wojciech Lieder

    2015-12-01

    Full Text Available The content of the article is an attempt to determine the course and consequences of terrorist attacks that took place in 2010 in Sweden and 2011 in Norway. A Comparative Study includes responses of societies and political elites of both countries.

  16. INOPS Survey data report for Sweden

    DEFF Research Database (Denmark)

    Lindholst, Andrej Christian; Severin, Majbritt Christine

    This data report provides statistics on the organization, management and performance of different ways of providing maintenance services within the municipal park and road sector(s) in Sweden. The statistics rely on data collected in the period from May 2015 to June 2015 through an online survey...

  17. Atomoxetine's Effect on Societal Costs in Sweden

    Science.gov (United States)

    Myren, Karl-Johan; Thernlund, Gunilla; Nylen, Asa; Schacht, Alexander; Svanborg, Par

    2010-01-01

    Objective: To compare societal costs between patients treated with atomoxetine and placebo in Sweden. Method: Ninety-nine pediatric ADHD patients were randomized to a 10-week double-blind treatment with atomoxetine (n = 49) or placebo (n = 50). All parents received four sessions of psycho-education. Parents filled out a resource utilization…

  18. Public Dialogue on Science in Sweden.

    Science.gov (United States)

    Dyring, Annagreta

    1988-01-01

    Explains how Sweden has proceeded to popularize science. Addresses topics dealing with policy, the energy debate, booklets with large circulation, computers and society, contacts between schools and research, building up small science centers, mass media, literary quality, children's responsibility, and some of the challenges. (RT)

  19. Consequences in Sweden of the Chernobyl accident

    International Nuclear Information System (INIS)

    Snihs, J.O.

    1986-01-01

    It summarizes the consequences in Sweden of the Chernobyl accident, describes the emergency response, the basis for decisions and countermeasures, the measurement strategies, the activity levels and doses and countermeasures and action levels used. Past and remaining problems are discussed and the major investigations and improvements are given. (author)

  20. The history of nuclear power in Sweden

    International Nuclear Information System (INIS)

    Larsson, K.E.

    1987-01-01

    The nuclear power developments in Sweden are reviewed, from the first initiatives to start research in the area in 1945 to the parliament decision in 1979 to phase out nuclear power by 2010. The article is primarily concerned with the political and R and D management aspects in the field. (L.E.)

  1. Reconsidering School Politics: Educational Controversies in Sweden

    Science.gov (United States)

    Fredholm, Axel

    2017-01-01

    School politics in Sweden has recently moved in a conservative direction, emphasising the importance of conventional school subjects, stronger teacher authority and more discipline in the classroom. At the same time, consensus on the utility of such measures is lacking in the school debate. The conservative approach is often criticised as…

  2. C. h. p. saves fuel in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Daugas, C F

    1979-04-01

    A combined heat and power plant based on a diesel generator to produce 12MW of electricity and 12MW of heat has successfully supplied the town of Skultuna in Sweden during the winter and has saved 3,700t of oil annually.

  3. Yoshio Nakajima. A Japanese Artist from Sweden

    DEFF Research Database (Denmark)

    Ørum, Tania

    2015-01-01

    Yoshio Nakajima is an interesting example of the globalisation of art. His education and early work as an artist took place in his native Japan, but continued in Europe where he has spent more than 30 years, mainly in provincial Sweden....

  4. Mobility of Knowledge as a Recognition Challenge: Experiences from Sweden

    Science.gov (United States)

    Andersson, Per; Fejes, Andreas

    2010-01-01

    This article focuses on the tensions between mobility, knowledge and recognition, and what the impact of migration could be on lifelong education and society. This is discussed with the case of Sweden as the starting point. The main issue in Sweden concerning migration is the admission of refugees. Sweden has had a relatively open policy…

  5. Sickness presenteeism in Norway and Sweden

    Directory of Open Access Journals (Sweden)

    Vegard Johansen

    2013-01-01

    Full Text Available Introduction: Sickness presenteeism (SP refers to the practice of going to work despite illness. This article describes the distribution of SP in Norway and Sweden. It also discusses relations between SP and various work characteristics and personal factors in the two countries. Methods: More than 2500 Norwegian and Swedish workers between 20 and 60 years of age answered a postal questionnaire. The Norwegian and Swedish samples are weighed and representative with regard to both variables of regional background and demography, but the response rate was low. The distribution of SP is measured by frequency (episodes in the previous year and by length (total days of SP in the previous year. This study employed binary and multinomial logistic regression to detect which factors influence the frequency of SP. Results: Fifty-five per cent of the respondents in Norway and Sweden practised SP in the previous year. The frequency of SP episodes is similar in the two countries. Further, respondents with low/medium income, physical work, and managerial responsibilities report SP more often in both countries. Non-western immigrants, the less educated, and those employed by others are overrepresented with SP in Norway. Neither gender nor age had any particular influence. Discussion: In accordance with previous studies, this study among Norwegian and Swedish workers suggests that some SP during a working year may be more common than no SP. Our analyses of determinants of SP present some previously undocumented differences. Divisions between sedentary versus physical work and management versus non-management were important for SP in Norway and Sweden. Moreover, non-western immigrants are overrepresented with SP in Norway, but this pattern does not prevail in Sweden. Some possible causes for non-western immigrants to report more SP are suggested in the article, but we need more research to follow up on the missing correlation between ethnic background and SP in

  6. Biogenic gas in the Cambrian-Ordovcian Alum Shale (Denmark and Sweden)

    Energy Technology Data Exchange (ETDEWEB)

    Schulz, H.M.; Wirth, R.; Biermann, S.; Arning, E.T. [Helmholtz-Zentrum Potsdam - Deutsches GeoForschungsZentrum GFZ, Potsdam (Germany); Krueger, M.; Straaten, N. [BGR Hannover (Germany); Bechtel, A. [Montanuniv. Leoben (Austria); Berk, W. van [Technical Univ. of Clausthal (Germany); Schovsbo, N.H. [Geological Survey of Denmark and Greenland - GEUS, Copenhagen (Denmark); Crabtree, Stephen [Gripen Gas (Sweden)

    2013-08-01

    Shale gas is mainly produced from thermally mature black shales. However, biogenic methane also represents a resource which is often underestimated. Today biogenic methane is being produced from the Upper Devonian Antrim Shale in the Michigan Basin which was the most successfully exploited shale gas system during the 1990-2000 decade in the U.S.A. before significant gas production from the Barnett Shale started (Curtis et al., 2008). The Cambro-Ordovician Alum Shale in northern Europe has thermal maturities ranging from overmature in southern areas (Denmark and southern Sweden) to immature conditions (central Sweden). Biogenic methane is recorded during drilling in central Sweden. The immature Alum Shale in central Sweden has total organic carbon (TOC) contents up to 20 wt%. The hydrogen index HI ranges from 380 to 560 mgHC/gTOC at very low oxygen index (OI) values of around 4 mg CO{sub 2}/gTOC, Tmax ranges between 420 - 430 C. The organic matter is highly porous. In general, the Alum Shale is a dense shale with intercalated sandy beds which may be dense due to carbonate cementation. Secondary porosity is created in some sandy beds due to feldspar dissolution and these beds serve as gas conduits. Methane production rates with shale as substrate in the laboratory are dependent on the kind of hydrocarbon-degrading microbial enrichment cultures used in the incubation experiments, ranging from 10-620 nmol/(g*d). In these experiments, the CO{sub 2} production rate was always higher than for methane. Like the northern part of North America, also Northern European has been covered by glaciers during the Pleistocene and similar geological processes may have developed leading to biogenic shale gas formation. For the Antrim Shale one hypothesis suggests that fresh waters, recharged from Pleistocene glaciation and modern precipitation, suppressed basinal brine salinity along the northern margins of the Michigan Basin to greater depths and thereby enhancing methanogenesis

  7. Long term variations of extreme rainfall in Denmark and southern Sweden

    DEFF Research Database (Denmark)

    Gregersen, Ida Bülow; Madsen, Henrik; Rosbjerg, Dan

    2015-01-01

    A high number of studies have detected changes in the observed heavy rainfall in Northern and Central Europe, all adding to the debate on anthropogenic climate change and its potential impact on rainfall extremes. However, it is equally relevant to understand natural variations on which...... the anthropogenic changes are imposed. This study identifies multi-decadal variations in daily rainfall extremes from Denmark and southern Sweden, with a recurrence level relevant for flood hazard analysis. Based on smoothed series it is concluded that the frequency of the extreme events shows both a general...

  8. Reverse-namaskar: A new sign in Ehlers-Danlos syndrome: A family pedigree study of four generations

    Directory of Open Access Journals (Sweden)

    Premalatha S

    2010-01-01

    Full Text Available Ehlers-Danlos Syndrome (EDS is a rare group of inheritable connective tissue disorder of defective collagen. Skin, joints and blood vessels are most commonly affected. Clinical signs such as Gorlin sign and Metenier sign have been described in this syndrome. We report another new clinical sign called ′Reverse-Namaskar′ sign as an important clinical finding in EDS, based on the family pedigree study of the proband.

  9. PedGenie: an analysis approach for genetic association testing in extended pedigrees and genealogies of arbitrary size

    Directory of Open Access Journals (Sweden)

    Camp Nicola J

    2006-04-01

    Full Text Available Abstract Background We present a general approach to perform association analyses in pedigrees of arbitrary size and structure, which also allows for a mixture of pedigree members and independent individuals to be analyzed together, to test genetic markers and qualitative or quantitative traits. Our software, PedGenie, uses Monte Carlo significance testing to provide a valid test for related individuals that can be applied to any test statistic, including transmission disequilibrium statistics. Single locus at a time, composite genotype tests, and haplotype analyses may all be performed. We illustrate the validity and functionality of PedGenie using simulated and real data sets. For the real data set, we evaluated the role of two tagging-single nucleotide polymorphisms (tSNPs in the DNA repair gene, NBS1, and their association with female breast cancer in 462 cases and 572 controls selected to be BRCA1/2 mutation negative from 139 high-risk Utah breast cancer families. Results The results from PedGenie were shown to be valid both for accurate p-value calculations and consideration of pedigree structure in the simulated data set. A nominally significant association with breast cancer was observed with the NBS1 tSNP rs709816 for carriage of the rare allele (OR = 1.61, 95% CI = 1.10–2.35, p = 0.019. Conclusion PedGenie is a flexible and valid statistical tool that is intuitively simple to understand, makes efficient use of all the data available from pedigrees without requiring trimming, and is flexible to the types of tests to which it can be applied. Further, our analyses of real data indicate NBS1 may play a role in the genetic etiology of heritable breast cancer.

  10. A colony of dog guides: analysis of the genetic variability assessed by pedigree data

    Directory of Open Access Journals (Sweden)

    Roberta Ciampolini

    2010-01-01

    Full Text Available The study presents the analysis of the genetic variability in a colony of dog guides. Three breeds, Labrador (L, Golden Retriever (GR, and German Shepherd (GS, were evaluated. Pedigrees data on 370 L, 260 GR, and 85 GS dogs bred for guide by the National Guide Dog School (SNCG of Scandicci (Florence, Italy were used. Data were available beginning from 1994. The average coefficient of coancestry and the mean F were 0.8% and 0.45% in GR, 0.7% and 0.38% in L, 1.0% and 0.49% in GS, respectively. The rate of increase in inbreeding was lower in L population (0.17 than in GR population (0.54, while in GS only the dogs with 5 e 7 traced generations resulted inbred. The results of this research point out that the genetic management of the dogs seems to be carefully and rationally monitored. Nevertheless, the population that may require a greater attention seems to be the GR, where a higher increase of the coefficient of inbreeding per generation is observed; therefore, the importation of germplasm from other working dogs is desirable in order to avoid in future an excessive increase of the inbreeding that could lead to adverse consequences for dogs health and fertility.

  11. Efficient computation of the joint probability of multiple inherited risk alleles from pedigree data.

    Science.gov (United States)

    Madsen, Thomas; Braun, Danielle; Peng, Gang; Parmigiani, Giovanni; Trippa, Lorenzo

    2018-06-25

    The Elston-Stewart peeling algorithm enables estimation of an individual's probability of harboring germline risk alleles based on pedigree data, and serves as the computational backbone of important genetic counseling tools. However, it remains limited to the analysis of risk alleles at a small number of genetic loci because its computing time grows exponentially with the number of loci considered. We propose a novel, approximate version of this algorithm, dubbed the peeling and paring algorithm, which scales polynomially in the number of loci. This allows extending peeling-based models to include many genetic loci. The algorithm creates a trade-off between accuracy and speed, and allows the user to control this trade-off. We provide exact bounds on the approximation error and evaluate it in realistic simulations. Results show that the loss of accuracy due to the approximation is negligible in important applications. This algorithm will improve genetic counseling tools by increasing the number of pathogenic risk alleles that can be addressed. To illustrate we create an extended five genes version of BRCAPRO, a widely used model for estimating the carrier probabilities of BRCA1 and BRCA2 risk alleles and assess its computational properties. © 2018 WILEY PERIODICALS, INC.

  12. Gene mapping in an anophthalmic pedigree of a consanguineous Pakistani family opened new horizons for research

    Directory of Open Access Journals (Sweden)

    Saleha S

    2016-06-01

    Full Text Available Clinical anophthalmia is a rare inherited disease of the eye and phenotype refers to the absence of ocular tissue in the orbit of eye. Patients may have unilateral or bilateral anophthalmia, and generally have short palpebral fissures and small orbits. Anophthalmia may be isolated or associated with a broader syndrome and may have genetic or environmental causes. However, genetic cause has been defined in only a small proportion of cases, therefore, a consanguineous Pakistani family of the Pashtoon ethnic group, with isolated clinical anophthalmia was investigated using linkage mapping. A family pedigree was created to trace the possible mode of inheritance of the disease. Blood samples were collected from affected as well as normal members of this family, and screened for disease-associated mutations. This family was analyzed for linkage to all the known loci of clinical anophthalmia, using microsatellite short tandem repeat (STR markers. Direct sequencing was performed to find out disease-associated mutations in the candidate gene. This family with isolated clinical anophthalmia, was mapped to the SOX2 gene that is located at chromosome 3q26.3-q27. However, on exonic and regulatory regions mutation screening of the SOX2 gene, the disease-associated mutation was not identified. It showed that another gene responsible for development of the eye might be present at chromosome 3q26.3-q27 and needs to be identified and screened for the disease-associated mutation in this family.

  13. Gene mapping in an anophthalmic pedigree of a consanguineous Pakistani family opened new horizons for research

    Science.gov (United States)

    Ajmal, M; Zafar, S; Hameed, A

    2016-01-01

    ABSTRACT Clinical anophthalmia is a rare inherited disease of the eye and phenotype refers to the absence of ocular tissue in the orbit of eye. Patients may have unilateral or bilateral anophthalmia, and generally have short palpebral fissures and small orbits. Anophthalmia may be isolated or associated with a broader syndrome and may have genetic or environmental causes. However, genetic cause has been defined in only a small proportion of cases, therefore, a consanguineous Pakistani family of the Pashtoon ethnic group, with isolated clinical anophthalmia was investigated using linkage mapping. A family pedigree was created to trace the possible mode of inheritance of the disease. Blood samples were collected from affected as well as normal members of this family, and screened for disease-associated mutations. This family was analyzed for linkage to all the known loci of clinical anophthalmia, using microsatellite short tandem repeat (STR) markers. Direct sequencing was performed to find out disease-associated mutations in the candidate gene. This family with isolated clinical anophthalmia, was mapped to the SOX2 gene that is located at chromosome 3q26.3-q27. However, on exonic and regulatory regions mutation screening of the SOX2 gene, the disease-associated mutation was not identified. It showed that another gene responsible for development of the eye might be present at chromosome 3q26.3-q27 and needs to be identified and screened for the disease-associated mutation in this family. PMID:27785411

  14. Familial history, age and smoking are important risk factors for disc degeneration disease in Arabic pedigrees

    International Nuclear Information System (INIS)

    Livshits, Gregory; Cohen, Zvi; Higla, Orabi; Yakovenko, Konstantin

    2001-01-01

    The present study used computed tomography imaging to evaluate the extent and pattern of the intergenerational transmission of spinal disc degeneration disease (DDD) in complex pedigrees. Contribution of a number of the potential covariates was also studied using univariate and multivariate logistic regression analysis, as well as two types of complex segregation analysis models. Among 161 individuals studied, DDD was diagnosed in 60 individuals. The number of protruded discs varied from 1 to 4, mostly in lumbar or lumbosacral regions. The average age at onset of the disease was similar for both women (36.0 years) and men (34.8 years). The proportion of the individuals affected by the DDD status of their parents ranged from 10% in families of two healthy parents to 55.5% of two affected parents (p < 0.01). The results of the logistic regression analyses and complex segregation analysis were qualitatively the same: DDD status of parents, age and smoking were the main risk factors for disc herniation in the Arabic families we examined. All analyses showed a predominating role of the family history as a risk factor for DDD in offsprings. It showed, for example, four times higher risk at age 50 for individuals with two affected parents vs. those who have two non-affected parents. However, the results of models-fitting genetic analysis, did not confirm a monogenic Mendelian pattern of inheritance

  15. Premenstrual mood symptoms: study of familiality and personality correlates in mood disorder pedigrees.

    Science.gov (United States)

    Payne, Jennifer L; Klein, Sarah R; Zamoiski, Rachel B; Zandi, Peter P; Bienvenu, Oscar J; Mackinnon, Dean F; Mondimore, Francis M; Schweizer, Barbara; Swartz, Karen L; Crowe, Raymond P; Scheftner, William A; Weissman, Myrna M; Levinson, Douglas F; DePaulo, J Raymond; Potash, James B

    2009-02-01

    We sought to determine whether premenstrual mood symptoms exhibit familial aggregation in bipolar disorder or major depression pedigrees. Two thousand eight hundred seventy-six women were interviewed with the Diagnostic Interview for Genetic Studies as part of either the NIMH Genetics Initiative Bipolar Disorder Collaborative study or the Genetics of Early Onset Major Depression (GenRED) study and asked whether they had experienced severe mood symptoms premenstrually. In families with two or more female siblings with bipolar disorder (BP) or major depressive disorder (MDD), we examined the odds of having premenstrual mood symptoms given one or more siblings with these symptoms. For the GenRED MDD sample we also assessed the impact of personality as measured by the NEO-FFI. Premenstrual mood symptoms did not exhibit familial aggregation in families with BP or MDD. We unexpectedly found an association between high NEO openness scores and premenstrual mood symptoms, but neither this factor, nor NEO neuroticism influenced evidence for familial aggregation of symptoms. Limitations include the retrospective interview, the lack of data on premenstrual dysphoric disorder, and the inability to control for factors such as medication use.

  16. Effectiveness of 10 polymorphic microsatellite markers for parentage and pedigree analysis in plateau pika (Ochotona curzoniae

    Directory of Open Access Journals (Sweden)

    Zhang Yanming

    2010-11-01

    Full Text Available Abstract Background The plateau pika (Ochotona curzoniae is an underground-dwelling mammal, native to the Tibetan plateau of China. A set of 10 polymorphic microsatellite loci has been developed earlier. Its reliability for parentage assignment has been tested in a plateau pika population. Two family groups with a known pedigree were used to validate the power of this set of markers. Results The error in parentage assignment using a combination of these 10 loci was very low as indicated by their power of discrimination (0.803 - 0.932, power of exclusion (0.351 - 0.887, and an effectiveness of the combined probability of exclusion in parentage assignment of 99.999%. Conclusion All the offspring of a family could be assigned to their biological mother; and their father or relatives could also be identified. This set of markers therefore provides a powerful and efficient tool for parentage assignment and other population analyses in the plateau pika.

  17. Two novel mutations in the PPIB gene cause a rare pedigree of osteogenesis imperfecta type IX.

    Science.gov (United States)

    Jiang, Yu; Pan, Jingxin; Guo, Dongwei; Zhang, Wei; Xie, Jie; Fang, Zishui; Guo, Chunmiao; Fang, Qun; Jiang, Weiying; Guo, Yibin

    2017-06-01

    Osteogenesis imperfecta (OI) is a rare genetic skeletal disorder characterized by increased bone fragility and vulnerability to fractures. PPIB is identified as a candidate gene for OI-IX, here we detect two pathogenic mutations in PPIB and analyze the genotype-phenotype correlation in a Chinese family with OI. Next-generation sequencing (NGS) was used to screen the whole exome of the parents of proband. Screening of variation frequency, evolutionary conservation comparisons, pathogenicity evaluation, and protein structure prediction were conducted to assess the pathogenicity of the novel mutations. Sanger sequencing was used to confirm the candidate variants. RTQ-PCR was used to analyze the PPIB gene expression. All mutant genes screened out by NGS were excluded except PPIB. Two novel heterozygous PPIB mutations (father, c.25A>G; mother, c.509G>A) were identified in relation to osteogenesis imperfecta type IX. Both mutations were predicted to be pathogenic by bioinformatics analysis and RTQ-PCR analysis revealed downregulated PPIB expression in the two carriers. We report a rare pedigree with an autosomal recessive osteogenesis imperfecta type IX (OI-IX) caused by two novel PPIB mutations identified for the first time in China. The current study expands our knowledge of PPIB mutations and their associated phenotypes, and provides new information on the genetic defects associated with this disease for clinical diagnosis. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Timing of the uv mutagenesis in yeast: a pedigree analysis of induced recessive mutation

    International Nuclear Information System (INIS)

    James, A.P.; Kilbey, B.J.

    1977-01-01

    The mechanism of uv-induced mutation in eukaryotes was studied in individual yeast cells by a procedure that combined pedigree analysis and tetrad analysis. The technique involved the induction of recessive lethals and semilethals in G1 diploid cells. Induced frequencies were 25 and 61% at survival levels of 90 and 77%, respectively. No evidence of gross chromosome aberrations was detected. Recessive mutations that affect only one strand or that affect both strands of the DNA molecule are induced much at random among a population of cells, and both types can occur within the same cell. However, the data confirm that two-strand mutations are in the majority after a low level of irradiation. The simplest explanation involves a mechanism whereby most mutations are fixed in both strands prior to the first round of post-irradiation DNA replication. The recessive mutational consequences of irradiation are exhausted at the conclusion of the first post-irradiation cell division, although dominant-lethal sectoring continues at a high level through the second post-irradiation division. It is concluded that pyrimidine dimers that persist to the second round of DNA replication are rare or ineffective

  19. The timing of UV mutagenesis in yeast: a pedigree analysis of induced recessive mutation.

    Science.gov (United States)

    James, A P; Kilbey, B J

    1977-10-01

    The mechanism of UV-induced mutation in eukaryotes was studied in individual yeast cells by a procedure that combined pedigree analysis and tetrad analysis. The technique involved the induction of recessive lethals and semilethals in G1 diploid cells. Induced frequencies were 25 and 61 percent at survival levels of 90 and 77 percent, respectively. No evidence of gross chromosome aberrations was detected. Recessive mutations that affect only one strand or that affect both strands of the DNA molecule are induced much at random among a population of cells, and both types can occur within the same cell. However, the data confirm that two-strand mutations are in the majority after a low level of irradiation. The simplest explanation involves a mechanism whereby most mutations are fixed in both strands prior to the first round of post-irradiation DNA replication. The recessive mutational consequences of irradiation are exhausted at the conclusion of the first post-irradiation cell division, although dominant-lethal sectoring continues at a high level through the second post-irradiation division. It is concluded that pyrimidine dimers that persist to the second round of DNA replication are rare or ineffective.

  20. Mortality and morbidity due to gastric dilatation-volvulus syndrome in pedigree dogs in the UK.

    Science.gov (United States)

    Evans, Katy M; Adams, Vicki J

    2010-07-01

    To estimate breed-specific risk of death due to, and prevalence of, gastric dilatation-volvulus (GDV) in UK pedigree dogs. Data were available on the reported cause of and age at death and occurrence of and age at diagnosis of disease from the 2004 purebred dog health survey. A total of 15,881 dogs of 165 breeds had died in the previous 10 years; GDV was the cause of death in 65 breeds. There were 36,006 live dogs of 169 breeds of which 48 breeds had experienced > or =1 episodes of GDV. Prevalence ratios were used to estimate breed-specific GDV mortality and morbidity risks. Gastric dilatation-volvulus was the cause of death for 389 dogs, representing 2.5% (95% CI: 2.2-2.7) of all deaths reported and the median age at death was 7.92 years. There were 253 episodes in 238 live dogs. The median age at first diagnosis was five years. Breeds at greatest risk of GDV mortality were the bloodhound, Grand Bleu de Gascogne, German longhaired pointer and Neapolitan mastiff. Breeds at greatest risk of GDV morbidity were the Grand Bleu de Gascogne, bloodhound, otterhound, Irish setter and Weimaraner. These results suggest that 16 breeds, mainly large/giant, are at increased risk of morbidity/mortality due to GDV.

  1. Identification of four novel mutations of the WFS1 gene in Iranian Wolfram syndrome pedigrees.

    Science.gov (United States)

    Ghahraman, Martha; Abbaszadegan, Mohammad Reza; Vakili, Rahim; Hosseini, Sousan; Fardi Golyan, Fatemeh; Ghaemi, Nosrat; Forghanifard, Mohammad Mahdi

    2016-12-01

    Wolfram syndrome is a rare neurodegenerative disorder with an autosomal recessive pattern of inheritance characterized by various clinical manifestations. The related gene, WFS1, encodes a transmembrane glycoprotein, named wolframin. Genetic analyses demonstrated that mutations in this gene are associated with WS type 1. Our aim in this study was to sequence WFS1 coding region in Iranian Wolfram syndrome pedigrees. Genomic DNA was extracted from peripheral blood of 12 WS patients and their healthy parents. Exons 2-8 and the exon-intron junctions of WFS1 were sequenced. DNA sequences were compared to the reference using Sequencher software. Molecular analysis of WFS1 revealed six different mutations. Four novel and two previously reported mutations were identified. One novel mutation, c.1379_1381del, is predicted to produce an aberrant protein. A second novel mutation, c.1384G > T, encodes a truncated protein. Novel mutation, c.1097-1107dup (11 bp), causes a frameshift which results in a premature stop codon. We screened for the novel missense mutation, c.1010C > T, in 100 control alleles. This mutation was not found in any of the healthy controls. Our study increased the spectrum of WFS1 mutations and supported the role of WFS1 in susceptibility to WS. We hope that these findings open new horizons to future molecular investigations which may help to prevent and treat this devastating disease.

  2. Novel pedigree analysis implicates DNA repair and chromatin remodeling in multiple myeloma risk.

    Science.gov (United States)

    Waller, Rosalie G; Darlington, Todd M; Wei, Xiaomu; Madsen, Michael J; Thomas, Alun; Curtin, Karen; Coon, Hilary; Rajamanickam, Venkatesh; Musinsky, Justin; Jayabalan, David; Atanackovic, Djordje; Rajkumar, S Vincent; Kumar, Shaji; Slager, Susan; Middha, Mridu; Galia, Perrine; Demangel, Delphine; Salama, Mohamed; Joseph, Vijai; McKay, James; Offit, Kenneth; Klein, Robert J; Lipkin, Steven M; Dumontet, Charles; Vachon, Celine M; Camp, Nicola J

    2018-02-01

    The high-risk pedigree (HRP) design is an established strategy to discover rare, highly-penetrant, Mendelian-like causal variants. Its success, however, in complex traits has been modest, largely due to challenges of genetic heterogeneity and complex inheritance models. We describe a HRP strategy that addresses intra-familial heterogeneity, and identifies inherited segments important for mapping regulatory risk. We apply this new Shared Genomic Segment (SGS) method in 11 extended, Utah, multiple myeloma (MM) HRPs, and subsequent exome sequencing in SGS regions of interest in 1063 MM / MGUS (monoclonal gammopathy of undetermined significance-a precursor to MM) cases and 964 controls from a jointly-called collaborative resource, including cases from the initial 11 HRPs. One genome-wide significant 1.8 Mb shared segment was found at 6q16. Exome sequencing in this region revealed predicted deleterious variants in USP45 (p.Gln691* and p.Gln621Glu), a gene known to influence DNA repair through endonuclease regulation. Additionally, a 1.2 Mb segment at 1p36.11 is inherited in two Utah HRPs, with coding variants identified in ARID1A (p.Ser90Gly and p.Met890Val), a key gene in the SWI/SNF chromatin remodeling complex. Our results provide compelling statistical and genetic evidence for segregating risk variants for MM. In addition, we demonstrate a novel strategy to use large HRPs for risk-variant discovery more generally in complex traits.

  3. Novel pedigree analysis implicates DNA repair and chromatin remodeling in multiple myeloma risk.

    Directory of Open Access Journals (Sweden)

    Rosalie G Waller

    2018-02-01

    Full Text Available The high-risk pedigree (HRP design is an established strategy to discover rare, highly-penetrant, Mendelian-like causal variants. Its success, however, in complex traits has been modest, largely due to challenges of genetic heterogeneity and complex inheritance models. We describe a HRP strategy that addresses intra-familial heterogeneity, and identifies inherited segments important for mapping regulatory risk. We apply this new Shared Genomic Segment (SGS method in 11 extended, Utah, multiple myeloma (MM HRPs, and subsequent exome sequencing in SGS regions of interest in 1063 MM / MGUS (monoclonal gammopathy of undetermined significance-a precursor to MM cases and 964 controls from a jointly-called collaborative resource, including cases from the initial 11 HRPs. One genome-wide significant 1.8 Mb shared segment was found at 6q16. Exome sequencing in this region revealed predicted deleterious variants in USP45 (p.Gln691* and p.Gln621Glu, a gene known to influence DNA repair through endonuclease regulation. Additionally, a 1.2 Mb segment at 1p36.11 is inherited in two Utah HRPs, with coding variants identified in ARID1A (p.Ser90Gly and p.Met890Val, a key gene in the SWI/SNF chromatin remodeling complex. Our results provide compelling statistical and genetic evidence for segregating risk variants for MM. In addition, we demonstrate a novel strategy to use large HRPs for risk-variant discovery more generally in complex traits.

  4. Evolution of the genetic variability of eight French dairy cattle breeds assessed by pedigree analysis.

    Science.gov (United States)

    Danchin-Burge, C; Leroy, G; Brochard, M; Moureaux, S; Verrier, E

    2012-06-01

    A pedigree analysis was performed on eight French dairy cattle breeds to assess their change in genetic variability since a first analysis completed in 1996. The Holstein, Normande and Montbéliarde breeds are selected internationally with over hundreds of thousands cows registered in the performance recording system. Three breeds are internationally selected but with limited numbers of cows in France (Brown Swiss, French Simmental and French Red Pied). The last two remaining breeds (Abondance and Tarentaise) are raised at regional level. The effective numbers of ancestors of cows born between 2004 and 2007 varied between 15 (Abondance and Tarentaise) and 51 (French Red Pied). The effective population sizes (classical approach) varied between 53 (Abondance) and 197 (French Red Pied). This article also compares the genetic variability of the ex situ (collections of the French National Cryobank) and in situ populations. The results were commented in regard to the recent history of gene flows in the different breeds as well as the existence of more or less stringent bottlenecks. Our results showed that whatever the size of the breeds, their genetic diversity impoverished quite rapidly since 1996 and they all could be considered as quite poor from a genetic diversity point of view. It shows the need for setting up cryobanks as gene reservoirs as well as sustainable breeding programmes that include loss of genetic diversity as an integrated control parameter. © 2011 Blackwell Verlag GmbH.

  5. Determination of genetic relatedness from low-coverage human genome sequences using pedigree simulations.

    Science.gov (United States)

    Martin, Michael D; Jay, Flora; Castellano, Sergi; Slatkin, Montgomery

    2017-08-01

    We develop and evaluate methods for inferring relatedness among individuals from low-coverage DNA sequences of their genomes, with particular emphasis on sequences obtained from fossil remains. We suggest the major factors complicating the determination of relatedness among ancient individuals are sequencing depth, the number of overlapping sites, the sequencing error rate and the presence of contamination from present-day genetic sources. We develop a theoretical model that facilitates the exploration of these factors and their relative effects, via measurement of pairwise genetic distances, without calling genotypes, and determine the power to infer relatedness under various scenarios of varying sequencing depth, present-day contamination and sequencing error. The model is validated by a simulation study as well as the analysis of aligned sequences from present-day human genomes. We then apply the method to the recently published genome sequences of ancient Europeans, developing a statistical treatment to determine confidence in assigned relatedness that is, in some cases, more precise than previously reported. As the majority of ancient specimens are from animals, this method would be applicable to investigate kinship in nonhuman remains. The developed software grups (Genetic Relatedness Using Pedigree Simulations) is implemented in Python and freely available. © 2017 John Wiley & Sons Ltd.

  6. Male-to-male transmission in extended pedigrees with multiple cases of autism

    Energy Technology Data Exchange (ETDEWEB)

    Hallmayer, J.; Spiker, D.; Lotspeich, L. [Stanford Univ., CA (United States)] [and others

    1996-02-16

    Despite strong genetic influences in autism, the true mode of inheritance remains unknown. Sex differences in autism have been described in both singleton and multiplex families: boys outnumber girls by 3 or 4 to 1, and so a sex-linked mode of transmission must also be considered. The key characteristic of X-linkage is that all sons of affected men are unaffected (no male-to-male transmission). In the present study, which is part of an ongoing linkage project in autism, we describe 77 multiplex autism families, 11 of who are affected cousin or half-sibling families. By using these families, it is possible to trace the path of genetic transmission and observe whether the hypothesis of X-linkage is tenable. Of 11 extended pedigrees from 77 multiplex families, six show male-to-male transmission; in these families, X-linkage can be excluded as the genetic basis for their autism. The data from the other five families are compatible with either an autosomal or an X-linked mode of transmission. The key point to emerge, then, is that autism cannot be exclusively an X-linked disorder; there must be an autosomal mode of transmission at least in some families. Thus we must consider the alternative hypotheses that autism is either entirely autosomal, or it is genetically heterogeneous, involving at least one autosomal locus with gender-specific expression, as well as a possible locus on the X-chromosome. 28 refs., 1 fig.

  7. The double pedigree: a method for studying culturally and genetically inherited behavior in tandem.

    Directory of Open Access Journals (Sweden)

    Etienne Danchin

    Full Text Available Transgenerational sources of biological variation have been at the center of evolutionary studies ever since Darwin and Wallace identified natural selection. This is because evolution can only operate on traits whose variation is transmitted, i.e. traits that are heritable. The discovery of genetic inheritance has led to a semantic shift, resulting in the tendency to consider that only genes are inherited across generations. Today, however, concepts of heredity are being broadened again to integrate the accruing evidence of non-genetic inheritance, and many evolutionary biologists are calling for the inclusion of non-genetic inheritance into an inclusive evolutionary synthesis. Here, we focus on social heredity and its role in the inheritance of behavioral traits. We discuss quantitative genetics methods that might allow us to disentangle genetic and non-genetic transmission in natural populations with known pedigrees. We then propose an experimental design based on cross-fostering among animal cultures, environments and families that has the potential to partition inherited phenotypic variation into socially (i.e. culturally and genetically inherited components. This approach builds towards a new conceptual framework based on the use of an extended version of the animal model of quantitative genetics to integrate genetic and cultural components of behavioral inheritance.

  8. Does perfectionism in bipolar disorder pedigrees mediate associations between anxiety/stress and mood symptoms?

    Science.gov (United States)

    Corry, Justine; Green, Melissa; Roberts, Gloria; Fullerton, Janice M; Schofield, Peter R; Mitchell, Philip B

    2017-10-06

    Bipolar disorder (BD) and the anxiety disorders are highly comorbid. The present study sought to examine perfectionism and goal attainment values as potential mechanisms of known associations between anxiety, stress and BD symptomatology. Measures of perfectionism and goal attainment values were administered to 269 members of BD pedigrees, alongside measures of anxiety and stress, and BD mood symptoms. Regression analyses were used to determine whether perfectionism and goal attainment values were related to depressive and (hypo)manic symptoms; planned mediation models were then used to test the potential for perfectionism to mediate associations between anxiety/stress and BD symptoms. Self-oriented perfectionism was associated with chronic depressive symptoms; socially-prescribed perfectionism was associated with chronic (hypo)manic symptoms. Self-oriented perfectionism mediated relationships between anxiety/stress and chronic depressive symptoms even after controlling for chronic hypomanic symptoms. Similarly, socially-prescribed perfectionism mediated associations between anxiety/stress and chronic hypomanic symptoms after controlling for chronic depressive symptoms. Goal attainment beliefs were not uniquely associated with chronic depressive or (hypo)manic symptoms. Cognitive styles of perfectionism may explain the co-occurrence of anxiety and stress symptoms and BD symptoms. Psychological interventions for anxiety and stress symptoms in BD might therefore address perfectionism in attempt to reduce depression and (hypo)manic symptoms in addition to appropriate pharmacotherapy.

  9. An instructive comparison of Denmark and Sweden CO2 emissions

    International Nuclear Information System (INIS)

    Huffer, E.; Nifenecker, H.

    2007-02-01

    Denmark and Sweden are close neighbors, they have pretty much the same Climate, so that it is interesting to try to understand what makes them so different in their per capita GHG (Green House Gas) emissions from fuel combustion. Indeed, the CO 2 emissions of Denmark and Sweden are practically equal while the population of Sweden is much larger. Thus, the per capita CO 2 emissions of Denmark are 63 % larger than those of Sweden. Denmark resorts heavily to fossil fuels for its production of both its electric power and its industrial heat whereas Sweden resorts to other primary energy sources which are either renewable or do not emit CO 2 . True, Sweden is in a privileged situation for its access to hydro power and to biomass but Denmark could considerably reduce its CO 2 emissions if it were to call on nuclear power as Sweden has been doing. (A.L.B.)

  10. Nord Stream, Sweden and Baltic Sea Security

    Energy Technology Data Exchange (ETDEWEB)

    Larsson, Robert L

    2007-03-15

    In June 2006, FOI published the report: Sweden and the NEGP: a Pilot Study of the North European Gas Pipeline and Sweden's Dependence on Russian Energy, a base data report on a topic that FOI considered to be of rising importance. Much has happened since then and the NEGP has changed its name to Nord Stream and submitted an official notification on the intention of realising the project of constructing a gas pipeline from Russia to Germany via the Baltic Sea. The primary aim of this report is to discuss and analyse some of the core aspects of Nord Stream and the pipeline project with regard to the security situation for the Baltic Sea region. The report constitutes an updated version of the previous report. Most of the old report still stands valid, especially concerning the historical survey of Russia's energy policy, but the new report has additional chapters and is broader in scope concerning the consequences of the project

  11. Chlamydia psittaci in birds of prey, Sweden

    Directory of Open Access Journals (Sweden)

    Maria Blomqvist

    2012-05-01

    Full Text Available Background: Chlamydia psittaci is an intracellular bacterium primarily causing respiratory diseases in birds but may also be transmitted to other animals, including humans. The prevalence of the pathogen in wild birds in Sweden is largely unknown. Methods: DNA was extracted from cloacae swabs and screened for C. psittaci by using a 23S rRNA gene PCR assay. Partial 16S rRNA and ompA gene fragments were sequence determined and phylogenies were analysed by the neighbour-joining method. Results and conclusion: The C. psittaci prevalence was 1.3% in 319 Peregrine Falcons and White-tailed Sea Eagles, vulnerable top-predators in Sweden. 16S rRNA and ompA gene analysis showed that novel Chlamydia species, as well as novel C. psittaci strains, are to be found among wild birds.

  12. Nord Stream, Sweden and Baltic Sea Security

    International Nuclear Information System (INIS)

    Larsson, Robert L.

    2007-03-01

    In June 2006, FOI published the report: Sweden and the NEGP: a Pilot Study of the North European Gas Pipeline and Sweden's Dependence on Russian Energy, a base data report on a topic that FOI considered to be of rising importance. Much has happened since then and the NEGP has changed its name to Nord Stream and submitted an official notification on the intention of realising the project of constructing a gas pipeline from Russia to Germany via the Baltic Sea. The primary aim of this report is to discuss and analyse some of the core aspects of Nord Stream and the pipeline project with regard to the security situation for the Baltic Sea region. The report constitutes an updated version of the previous report. Most of the old report still stands valid, especially concerning the historical survey of Russia's energy policy, but the new report has additional chapters and is broader in scope concerning the consequences of the project

  13. The Y2K issue in Sweden

    International Nuclear Information System (INIS)

    Dahlin, G.; Ek, P.; Isaksson, S.; Ericsson, A.M.; Jaernry, C.

    1999-01-01

    The paper overviews the work performed in Sweden on the Y2K issue. It describes in summary how the work is done at the utilities, some lessons learned and the work performed by the regulatory body, the Swedish Power Inspectorate. It discusses as well, how the reporting and accountancy has been changed to meet the Y2K problem at the Swedish State Authority as well as at the Swedish nuclear facilities. There is a section describing the Physical Protection issues

  14. Transportation of radioactive materials in Sweden

    International Nuclear Information System (INIS)

    Ericsson, A.M.

    1979-06-01

    This report is designed to calculate the total risk due to shipping radioactive materials in Sweden. The base case developed is the shipment model that is used now or the best estimate for expected shipments. The model for the calculations and the computer program used has been developed at the Sandia Laboratories, Albuquerque, N.M., USA and is the same that was used for the NUREG-0170 study. The results from the calculations show an annual expected population dose of 30 person-rem due to normal transport conditions. The annual expected dose from accidents were calculated to be between 2.3-20.8 person rem. The higher figure represents the case where plutonium is shipped back to Sweden from reprocessing plants abroad in the form of PuO2 and the lower figure represent the case when plutonium is shipped back in the form of mixed oxide fuel. The total additional population dose in Sweden due to both normal and accident conditions in the transportation of radioactive materials will be 30 - 50 person rem/year. Compared to the natural background radiation that is 8x10 5 person rem per year in Sweden, this figure is very low. If converted to latent cancer fatalities this population dose will add approximately 3.5x10 3 cancers each year. The consequences due to accidents have been calculated and are discussed separately from their probabilities. The most severe accident that was found was an accident involving PuO 2 . This accident would give 82 400 rem as a maximum individual dose and 8.1x10 5 person rem as a population dose. (Auth.)

  15. Citizens and taxation : Sweden in comparative perspective

    OpenAIRE

    Edlund, Jonas

    1999-01-01

    In the contemporary critique of the welfare state a common target is taxation. The consequences of the high levels of taxes collected by the modern state, the critics argue, are slowdown in economic growth, high unemployment, and declining public legitimacy for taxes and state provided welfare. This thesis explores the political support for taxation in Sweden, the epitome of high-tax-society. The thesis consists of one introductory chapter and five journal articles. The first objective of the...

  16. Radon problems in Sweden. Investigations and countermeasures

    International Nuclear Information System (INIS)

    Snihs, J.O.; Ehdwall, H.

    1978-11-01

    For some years radon has been of great concern in Sweden both as a source of occupational exposure in mines and other underground spaces and as a source of radiation exposures in dwellings has lately increased to a considerable extent and appropriate measurements and possible countermeasures are under intensive discussion. The policy and general principles of the supervision especially at work places are described here with a brief description of the progress of the development work on measuring methods. (author)

  17. Evaluating the gender wage gap in Sweden

    OpenAIRE

    Malmberg, Åsa

    2007-01-01

    Using mainly quantile regressions, this paper evaluates the gender wage gap throughout the conditional wage distribution in Sweden. The gender wage is found to increase at the upper tail of the wage distribution, indicating an enforcement of the glass ceiling effect recorded in earlier studies. The results also indicate that the earlier noted trend of diminishing wage differences at the bottom of the wage distribution now is turning. The increase of overall wage inequalities coincides with a ...

  18. Uranium recovery in Sweden. History and perspective

    International Nuclear Information System (INIS)

    Hultgren, Aa.; Olsson, G.

    1993-08-01

    In 1945 the potential of nuclear energy for military and peaceful purpose had initiated a strong interest in Sweden to establish a national programme in the field. The Atomic Energy Committee was formed at the end of 1945 and charged the Research Institute of National Defence in January 1946 with the test to investigate possibilities of uranium recovery in Sweden. AB Atomenergi, a semi-state owned body, was formed in November 1947 to take charge of nuclear energy related research and development. The search for and the recovery of uranium from indigenous resources became a dominant objective over the first years of the company. The report gives a broad overview of the efforts to establish a national uranium fuel supply programme in Sweden from the early days of the postwar years of the 1940s. Process and plant development, plant operations at Kvarntorp and Ranstad, and the development of the uranium supply policy are presented against a background of the nuclear power development in the country. The nuclear weapons debate and the decision to sign the non proliferation treaty in 1968 are briefly reported. Special attention has been given an account of the technical development and the various projects related to the Ranstad plant and its final restoration in the 1980s

  19. Consequences in Sweden of the Chernobyl accident

    International Nuclear Information System (INIS)

    Haegg, Conny.

    1990-01-01

    The radiation doses to man in Sweden due to the Chernobyl accident originate mainly from external irradiation from deposited radionuclides and internal irradiation from consumption of radioactively contaminated food stuffs. Inhalation and external irradiation from the passing cloud give only a minor contribution to the total dose. As an average for the Swedish population the individual radiation dose during the first year amounts to about 0.1 mSv, i.e. 10% of the natural background radiation. In the most contaminated areas, however, the individual dose may become 30 times higher than the average dose. The dose committed over 50 years has estimated to be about six times as high as the first year dose. The collective dose for the Swedish population has been estimated to about 1300 manSv the first year after the accident and the corresponding dose over 50 years to 5000 to 7000 manSv. This could lead to 100 to 200 extra fatal cancers. Furthermore, no damages on man that can be related to Chernobyl fallout, e.g. pre-natal effects, have so far been observed in Sweden. Shortly after the accident, several research projects were initiated in Sweden in order to follow the distribution of radionuclides in the aquatic and terrestrial environment. The results which in many cases are preliminary, shows that the recovery of the ecosystem will take several decades. (author)

  20. Systematic differences in the response of genetic variation to pedigree and genome-based selection methods.

    Science.gov (United States)

    Heidaritabar, M; Vereijken, A; Muir, W M; Meuwissen, T; Cheng, H; Megens, H-J; Groenen, M A M; Bastiaansen, J W M

    2014-12-01

    Genomic selection (GS) is a DNA-based method of selecting for quantitative traits in animal and plant breeding, and offers a potentially superior alternative to traditional breeding methods that rely on pedigree and phenotype information. Using a 60 K SNP chip with markers spaced throughout the entire chicken genome, we compared the impact of GS and traditional BLUP (best linear unbiased prediction) selection methods applied side-by-side in three different lines of egg-laying chickens. Differences were demonstrated between methods, both at the level and genomic distribution of allele frequency changes. In all three lines, the average allele frequency changes were larger with GS, 0.056 0.064 and 0.066, compared with BLUP, 0.044, 0.045 and 0.036 for lines B1, B2 and W1, respectively. With BLUP, 35 selected regions (empirical P selected regions were identified. Empirical thresholds for local allele frequency changes were determined from gene dropping, and differed considerably between GS (0.167-0.198) and BLUP (0.105-0.126). Between lines, the genomic regions with large changes in allele frequencies showed limited overlap. Our results show that GS applies selection pressure much more locally than BLUP, resulting in larger allele frequency changes. With these results, novel insights into the nature of selection on quantitative traits have been gained and important questions regarding the long-term impact of GS are raised. The rapid changes to a part of the genetic architecture, while another part may not be selected, at least in the short term, require careful consideration, especially when selection occurs before phenotypes are observed.

  1. Cattle Sex-Specific Recombination and Genetic Control from a Large Pedigree Analysis.

    Science.gov (United States)

    Ma, Li; O'Connell, Jeffrey R; VanRaden, Paul M; Shen, Botong; Padhi, Abinash; Sun, Chuanyu; Bickhart, Derek M; Cole, John B; Null, Daniel J; Liu, George E; Da, Yang; Wiggans, George R

    2015-11-01

    Meiotic recombination is an essential biological process that generates genetic diversity and ensures proper segregation of chromosomes during meiosis. From a large USDA dairy cattle pedigree with over half a million genotyped animals, we extracted 186,927 three-generation families, identified over 8.5 million maternal and paternal recombination events, and constructed sex-specific recombination maps for 59,309 autosomal SNPs. The recombination map spans for 25.5 Morgans in males and 23.2 Morgans in females, for a total studied region of 2,516 Mb (986 kb/cM in males and 1,085 kb/cM in females). The male map is 10% longer than the female map and the sex difference is most pronounced in the subtelomeric regions. We identified 1,792 male and 1,885 female putative recombination hotspots, with 720 hotspots shared between sexes. These hotspots encompass 3% of the genome but account for 25% of the genome-wide recombination events in both sexes. During the past forty years, males showed a decreasing trend in recombination rate that coincided with the artificial selection for milk production. Sex-specific GWAS analyses identified PRDM9 and CPLX1 to have significant effects on genome-wide recombination rate in both sexes. Two novel loci, NEK9 and REC114, were associated with recombination rate in both sexes, whereas three loci, MSH4, SMC3 and CEP55, affected recombination rate in females only. Among the multiple PRDM9 paralogues on the bovine genome, our GWAS of recombination hotspot usage together with linkage analysis identified the PRDM9 paralogue on chromosome 1 to be associated in the U.S. Holstein data. Given the largest sample size ever reported for such studies, our results reveal new insights into the understanding of cattle and mammalian recombination.

  2. Composition and sources of carbonaceous aerosols in Northern Europe during winter

    NARCIS (Netherlands)

    Glasius, M.; Hansen, A.M.K.; Claeys, M.; Henzing, J.S.; Jedynska, A.D.; Kasper-Giebl, A.; Kistler, M.; Kristensen, K.; Martinsson, J.; Maenhaut, W.; Nøjgaard, J.K.; Spindler, G.; Stenström, K.E.; Swietlicki, E.; Szidat, S.; Simpson, D.; Yttri, K.E.

    2018-01-01

    Sources of elemental carbon (EC) and organic carbon (OC) in atmospheric aerosols (carbonaceous aerosols) were investigated by collection of weekly aerosol filter samples at six background sites in Northern Europe (Birkenes, Norway; Vavihill, Sweden; Risoe, Denmark; Cabauw and Rotterdam in The

  3. Patterns in current perioperative practice: survey of colorectal surgeons in five northern European countries

    DEFF Research Database (Denmark)

    Lassen, K; Hannemann, P; Ljungqvist, O

    2005-01-01

    Evidence for optimal perioperative care in colorectal surgery is abundant. By avoiding fasting, intravenous fluid overload, and activation of the neuroendocrine stress response, postoperative catabolism is reduced and recovery enhanced. The specific measures that can be used routinely include...... in colorectal cancer surgery in five northern European countries: Scotland, the Netherlands, Denmark, Sweden, and Norway....

  4. Leaving Sweden behind: Gains in life expectancy in Canada.

    Science.gov (United States)

    Auger, Nathalie; Le Serbon, Emilie; Rostila, Mikael

    2015-06-01

    Sweden and Canada are known for quality of living and exceedingly high life expectancy, but recent data on how these countries compare are lacking. We measured life expectancy in Canada and Sweden during the past decade, and identified factors responsible for changes over time. We calculated life expectancy at birth for Canada and Sweden annually from 2000 to 2010, and determined the ages and causes of death responsible for the gap between the two countries using Arriaga's method. We determined how population growth, ageing, and mortality influenced the number of deaths over time. During 2000-2010, life expectancy in Canada caught up with Sweden for men, and surpassed Sweden by 0.4 years for women. Sweden lost ground owing to a slower reduction in circulatory and tumour mortality after age 65 years compared with Canada. Nonetheless, population ageing increased the number of deaths in Canada, especially for mental and nervous system disorders. In Sweden, the number of deaths decreased. In only one decade, life expectancy in Canada caught up and surpassed Sweden due to rapid improvements in circulatory and tumour mortality. Population ageing increased the number of deaths in Canada, potentially stressing the health care system more than in Sweden. © 2015 the Nordic Societies of Public Health.

  5. [The significance of pedigree genetic screening and rapid immunological parameters in the diagnosis of primary hemophagocytic lymphohistiocytosis].

    Science.gov (United States)

    Zhang, J; Wang, Y N; Wang, J S; Wu, L; Wei, N; Fu, L; Gao, Z; Chen, J H; Pei, R J; Wang, Z

    2016-07-01

    To investigate the significance of pedigree genetic screening and rapid immunological parameters in the diagnosis of primary hemophagocytic lymphohistiocytosis (HLH). Four cases of primary HLH patients with PRF1, UNC13D and SH2D1A gene mutations were conducted pedigree investigation, including family genetic screening and detections of immunological parameters (NK cell activity, CD107a degranulation and expression of HLH related defective protein), to evaluate the significance of these different indicators in the diagnosis of primary HLH and explore their correlations. The DNA mutations of the four families included missense mutation c.T172C (p.S58P) and non- frameshift deletions c.1083_1094del (p.361_365del), missense mutation c.C1349T (p.T450M) and frameshift mutation c.1090_1091delCT (p.T364fsX93) in PRF1 gene, missense mutation c.G2588A (p.G863D) in UNC13D gene and hemizygous mutation c.32T>G (p.I11S) in SH2D1A gene. The patients and their family members presented decreased NK cell activities. Individuals who carried mutations of PRF1 gene and SH2D1A gene showed low expression of perforin (PRF1) and signaling lymphocytic activation molecule associated protein (SAP). And the patient with UNC13D gene mutation and his family member with identical mutation showed significant reducing cytotoxic degranulation function (expression of CD107a). Pedigree genetic screening and rapid detection of immunological parameters might play an important role in the diagnosis of primary HLH, and both of them had good consistency. As an efficient detection means, the rapid immunological detection indicators would provide reliable basis for the early diagnosis of the primary HLH.

  6. Composition of atmospheric precipitation in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Emanuelsson, A; Eriksson, E; Egner, H

    1954-01-01

    Preliminary charts are presented based on two years of data, to demonstrate the geographic distribution over Sweden of the annual amounts of Na, Cl, K, Ca, NH/sub 3//sup -n/, and NO/sub 3//sup -n/ brought to the surface of the earth by precipitation. The ratios of these total amounts to the total amounts of Na deposited during the same time interval are shown to possess systematic geographic distribution patterns. Comparisons are made between these ratios and the corresponding quantities in sea water. The investigation is now being resumed to provide additional data from a larger number of stations and for longer time periods.

  7. Industrial action in Sweden - a new pattern?

    OpenAIRE

    Lindberg, Henrik

    2011-01-01

    The paper studies the modern conflict patterns and conflict dimensions in Sweden 1993-2005. The aim is to trace and interpret the new patterns and dimensions of labour market conflict by collecting and compiling strike data from the National Conciliation Office, (1993-99) and the National Mediation Office (2000-2005). On the whole, strike activity has decreased steadily from the 1980s and onwards and in large parts of the Swedish labour market conflicts are very rare. A few small un-ions orga...

  8. Buildings with enhanced radioactivity in Sweden

    International Nuclear Information System (INIS)

    Swedjemark, G.A.

    1980-12-01

    Enhanced radon/radon daughter concentrations indoors have been found in some houses in Sweden, especially in combination with low air exchange rates. The radon sources have been found to be some types of building materials, some types of filling materials, some types of ground and any combination of these sources. The radon source may also be radon-rich tap water. The same types of building materials also give an enhanced gamma radiation level. In all houses, both lower and higher concentrations of radon than the average levels given here have been found in individual rooms and with single measurements. (author)

  9. PRE-HOSPITAL EMERGENCY CARE IN SWEDEN

    Directory of Open Access Journals (Sweden)

    Ulf BJÖRNSTIG

    2004-01-01

    In Sweden (9 million inhabitants, a sparsely populated country with sometimes long transportation distances to the nearest trauma hospital, 800 ambulances, 7 ambulance helicopters and 3–5 fixed wing ambulance aircraft are the available transport resources. In case of a mass casualty or disaster situation, inside or outside the country, a governmental project (Swedish National Medevac aims to convert a passenger aircraft from Scandinavian Airlines System (SAS to a qualified medical resource for long distance transport, with capacity to nurse six intensive care patients and an additional 6–20 lieing or seated patients during transport.

  10. Country policy profile - Sweden. October 2014

    International Nuclear Information System (INIS)

    2014-10-01

    The main support mechanism for electricity from RES is a quota system that is based on a certificate trading system. Furthermore, tax incentives are in place and PV installations are subsidised with grants. Promotion of heating from RES is mainly promoted through tax exemptions. Households may deduct investments of renewable energy heating installations replacing heating systems based on fossil fuels from tax. Heating from RES further benefits from an exemption of various taxes, as carbon dioxide taxes on supply, import and production of fossil fuels for heating purposes, which apply for fossil fuels (Source, RES LEGAL Europe, www.res-legal.eu/search-by-country/sweden/)

  11. Household energy demand. Empirical studies concerning Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Dargay, J; Lundin, A

    1978-06-01

    This paper investigates the effects of energy policy on households in Sweden and provides the material necessary for evaluation of current and proposed energy-conservation measures. Emphasis is placed on the impact of enery taxation or price changes on household demand for electricity, heating oil, and gasoline and the consequences of such measures for income distribution. The results of the Swedish studies of household demand for heating oil and gasoline indicate that price changes can have a considerable long run impact on fuel utilization. In the short run, price responsiveness is notably reduced, but it is nevertheless of consequence for energy demand.

  12. National Debate and Public Confidence in Sweden

    International Nuclear Information System (INIS)

    Lindquist, Ted

    2014-01-01

    Ted Lindquist, coordinator of the Association of Swedish Municipalities with Nuclear Facilities (KSO), closed the first day of conferences. He showed what the nuclear landscape was in Sweden, and in particular that through time there has been a rather good support from the population. He explained that the reason could be the confidence of the public in the national debate. On a more local scale, Ted Lindquist showed how overwhelmingly strong the support was in towns where the industry would like to operate long-term storage facilities

  13. This is how we manage Sweden`s radioactive waste. Activities 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    SKB operates systems and facilities for the management and final disposal of spent nuclear fuel and other radioactive waste in Sweden. SKB has conducted extensive R, D and D work with regard to constructing a spent fuel encapsulation plant and a deep repository in crystalline bedrock. This annual report treats all the different activities without going into technical details.

  14. NMR-Based Metabolomic Investigations on the Differential Responses in Adductor Muscles from Two Pedigrees of Manila Clam Ruditapes philippinarum to Cadmium and Zinc

    Directory of Open Access Journals (Sweden)

    Junbao Yu

    2011-09-01

    Full Text Available Manila clam Ruditapes philippinarum is one of the most important economic species in shellfishery in China due to its wide geographic distribution and high tolerance to environmental changes (e.g., salinity, temperature. In addition, Manila clam is a good biomonitor/bioindicator in “Mussel Watch Programs” and marine environmental toxicology. However, there are several pedigrees of R. philippinarum distributed in the marine environment in China. No attention has been paid to the biological differences between various pedigrees of Manila clams, which may introduce undesirable biological variation in toxicology studies. In this study, we applied NMR-based metabolomics to detect the biological differences in two main pedigrees (White and Zebra of R. philippinarum and their differential responses to heavy metal exposures (Cadmium and Zinc using adductor muscle as a target tissue to define one sensitive pedigree of R. philippinarum as biomonitor for heavy metals. Our results indicated that there were significant metabolic differences in adductor muscle tissues between White and Zebra clams, including higher levels of alanine, glutamine, hypotaurine, phosphocholine and homarine in White clam muscles and higher levels of branched chain amino acids (valine, leucine and isoleucine, succinate and 4-aminobutyrate in Zebra clam muscles, respectively. Differential metabolic responses to heavy metals between White and Zebra clams were also found. Overall, we concluded that White pedigree of clam could be a preferable bioindicator/biomonitor in marine toxicology studies and for marine heavy metals based on the relatively high sensitivity to heavy metals.

  15. Targeted next generation sequencing identified a novel mutation in MYO7A causing Usher syndrome type 1 in an Iranian consanguineous pedigree.

    Science.gov (United States)

    Kooshavar, Daniz; Razipour, Masoumeh; Movasat, Morteza; Keramatipour, Mohammad

    2018-01-01

    Usher syndrome (USH) is characterized by congenital hearing loss and retinitis pigmentosa (RP) with a later onset. It is an autosomal recessive trait with clinical and genetic heterogeneity which makes the molecular diagnosis much difficult. In this study, we introduce a pedigree with two affected members with USH type 1 and represent a cost and time effective approach for genetic diagnosis of USH as a genetically heterogeneous disorder. Target region capture in the genes of interest, followed by next generation sequencing (NGS) was used to determine the causative mutations in one of the probands. Then segregation analysis in the pedigree was conducted using PCR-Sanger sequencing. Targeted NGS detected a novel homozygous nonsense variant c.4513G > T (p.Glu1505Ter) in MYO7A. The variant is segregating in the pedigree with an autosomal recessive pattern. In this study, a novel stop gained variant c.4513G > T (p.Glu1505Ter) in MYO7A was found in an Iranian pedigree with two affected members with USH type 1. Bioinformatic as well as pedigree segregation analyses were in line with pathogenic nature of this variant. Targeted NGS panel was showed to be an efficient method for mutation detection in hereditary disorders with locus heterogeneity. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Domestic gender equality and childbearing in Sweden

    Directory of Open Access Journals (Sweden)

    Frances Goldscheider

    2013-12-01

    Full Text Available Background: Sweden, which is among the most gender-equal societies in the world, combines 'modern' family patterns such as unmarried cohabitation, delayed parenthood, high maternal labor force participation, and high break-up rates - all usually linked with low birth rates - with relatively high fertility. Sweden also has a high level of shared parental responsibility for home and children. Objective: After decades of late 20th century research showing that increasing gender equality in the workplace was linked with lower fertility, might gender equality in the home increase fertility? Methods: Using data from the Swedish Young Adult Panel Study (YAPS, we use Cox regression to examine the effects on first, second, and third births of 1 holding attitudes about sharing equally in the care of the home and children, and 2 actual sharing in these domestic tasks. Results: Our analysis shows that, measuring attitudes before the transition to parenthood and actual practice four years later, it is inconsistency between sharing attitudes and the actual division of housework that reduces the likelihood of continued childbearing, especially on second births among women. Conclusions: As women are most likely to confront an inconsistent situation, with egalitarian ideals in a household without equal sharing, it is clear that having a partner who does not share housework is depressing Swedish fertility.

  17. Situation of nuclear power generation in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Sandstroem, S [Swedish Atomic Forum

    1978-01-01

    In Sweden, nuclear power generation was received initially favorably. In the end of 1960s, however, nuclear power generation got involved in the activities of environment preservation. Then, political parties became opposed to nuclear power generation, and now, the need of nuclear power generation itself is regarded as questionable. In the general election in 1976, the Government opposing the nuclear power generation won. As the result, the conditional nuclear power development law and the energy committee were set up. The committee composed of parliament members, experts, and representatives of enterprises and trade unions is to submit its report so that the parliament can prepare a new energy program in the fall of 1978. Meanwhile, the nuclear fuel safety project formed newly has studied to satisfy the conditions of the law. In Sweden, which has developed nuclear reactors independently from the technology of USA, the oppositions are on the decrease, however. It is awaited what decision will be made by the Government in this fall.

  18. Sweden: Combining childbearing and gender equality

    Directory of Open Access Journals (Sweden)

    Eva Bernhardt

    2008-07-01

    Full Text Available Sweden is the forerunner of the Second Demographic Transition. Fertility trends have fluctuated greatly since the 1960s, and the 1990s showed both European-highest and lowest-ever-in-Sweden levels, while the cohort pattern has been relatively stable. Period fluctuations have been accompanied by a postponement of entering committed partnerships and parenthood as well as an increasing instability of family relationships. The awareness and the availability of effective contraceptives have been extensive since the mid-1970s, the year the liberal abortion law was introduced. Post-modern values are dominant in this highly secularized society, but ideal family size is among the highest in the European Union, and childlessness has remained at a relatively low level. Ethnic diversification has increased over time, with about one-fifth of the population having a 'foreign background' in the early 2000s. The level of female labor-force participation is the highest in Europe (although mothers of pre-schoolers often work part-time, and young women are just as highly educated as men. Family policies, based on the principle of equality across social groups and gender, seem to play an important role in keeping fertility relatively high. In combination with other factors, family policies also play a role in the fluctuations of fertility rates, as eligibility to parental-leave and benefits as well as the availability of public childcare are linked to parents' labor-force attachment.

  19. Sweden to host a new neutron source

    CERN Multimedia

    Anaïs Schaeffer

    2012-01-01

    The first European neutron source, currently under development, should commence operations by the end of this decade. Its aim: to produce beams of neutrons that can penetrate into the heart of matter without damaging it and reveal its secrets.   An artist's impression of what the ESS should look like in 2019. At the southern end of Sweden, a town called Lund is preparing for the arrival of the world's most powerful neutron source: the European Spallation Source (ESS). Construction is scheduled to start at the beginning of next year, and the facility is expected to become operational by 2019, when it will produce its first neutron beams. “The ESS is the result of an idea that began 20 years ago!” underlines Mats Lindroos, in charge of the ESS Accelerator Division. “Today, 17 European countries support the project, including Sweden, Denmark and Norway, who together account for 50% of the construction funding.” The ESS, whose design is al...

  20. Nord Stream, Sweden and Baltic Sea Security

    Energy Technology Data Exchange (ETDEWEB)

    Larsson, Robert L.

    2007-03-15

    In June 2006, FOI published the report: Sweden and the NEGP: a Pilot Study of the North European Gas Pipeline and Sweden's Dependence on Russian Energy, a base data report on a topic that FOI considered to be of rising importance. Much has happened since then and the NEGP has changed its name to Nord Stream and submitted an official notification on the intention of realising the project of constructing a gas pipeline from Russia to Germany via the Baltic Sea. The primary aim of this report is to discuss and analyse some of the core aspects of Nord Stream and the pipeline project with regard to the security situation for the Baltic Sea region. The report constitutes an updated version of the previous report. Most of the old report still stands valid, especially concerning the historical survey of Russia's energy policy, but the new report has additional chapters and is broader in scope concerning the consequences of the project

  1. Spatial and temporal variations in glacier hydrology on Storglaciaeren, Sweden

    International Nuclear Information System (INIS)

    Jansson, Peter; Naeslund, Jens-Ove

    2009-06-01

    The aim of the current research project was to provide a framework of real conditions within which to interpret theory and extrapolate likely conditions beneath a future ice sheet over Fennoscandia. The purpose of this report is to summarize the experimental work on glacier hydrology and basal hydraulic conditions performed on Storglaciaeren, northern Sweden, during the years 1990-2006. Surface fed subglacial hydrological systems are extremely dynamic because the input rates of rain and temperature-controlled surface melt fluctuate, and the geometry of flow paths is constantly changing due to ice deformation which tends to open and close the flow paths. The hydrological system of a glacier is quite unusual because since liquid water flows through conduits made of its solid phase (ice). Understanding the expected dynamic range of a glacier's hydrological system is best studied by in situ measurements. The processes studied on Storglaciaeren can be expected to apply to ice sheet scale, albeit on different spatial scales. Since Storglaciaeren is a polythermal glacier with a large fraction of ice below freezing and at the melting point and with a surface-fed hydrological system of conduits and tunnels, results apply to the lower elevation regions where the surface is composed of ice (ablation zone) rather than composed of snow (accumulation zone) found at higher elevations of the glaciers and ice sheets, Therefore, our results apply to the ablation zone of the past Fennoscandian Ice Sheet. In this report we discuss the measurements made to assess the subglacial conditions that provide a potential analogue for conditions under the Fennoscandian Ice Sheet. For this purpose field work was performed on from 2003 to 2006 yielding subglacial water pressure measurements. We have included a large quantity of unpublished data from Storglaciaeren from different research projects conducted since 1990. Together these data provide a picture of the temporal and spatial water

  2. Spatial and temporal variations in glacier hydrology on Storglaciaeren, Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Jansson, Peter (Dept. of Physical Geography and Quaternary Geology, Stockholm Univ., Stockholm (Sweden)); Naeslund, Jens-Ove (Swedish Nuclear Fuel and Waste Management Co., Stockholm (Sweden))

    2009-06-15

    The aim of the current research project was to provide a framework of real conditions within which to interpret theory and extrapolate likely conditions beneath a future ice sheet over Fennoscandia. The purpose of this report is to summarize the experimental work on glacier hydrology and basal hydraulic conditions performed on Storglaciaeren, northern Sweden, during the years 1990-2006. Surface fed subglacial hydrological systems are extremely dynamic because the input rates of rain and temperature-controlled surface melt fluctuate, and the geometry of flow paths is constantly changing due to ice deformation which tends to open and close the flow paths. The hydrological system of a glacier is quite unusual because since liquid water flows through conduits made of its solid phase (ice). Understanding the expected dynamic range of a glacier's hydrological system is best studied by in situ measurements. The processes studied on Storglaciaeren can be expected to apply to ice sheet scale, albeit on different spatial scales. Since Storglaciaeren is a polythermal glacier with a large fraction of ice below freezing and at the melting point and with a surface-fed hydrological system of conduits and tunnels, results apply to the lower elevation regions where the surface is composed of ice (ablation zone) rather than composed of snow (accumulation zone) found at higher elevations of the glaciers and ice sheets, Therefore, our results apply to the ablation zone of the past Fennoscandian Ice Sheet. In this report we discuss the measurements made to assess the subglacial conditions that provide a potential analogue for conditions under the Fennoscandian Ice Sheet. For this purpose field work was performed on from 2003 to 2006 yielding subglacial water pressure measurements. We have included a large quantity of unpublished data from Storglaciaeren from different research projects conducted since 1990. Together these data provide a picture of the temporal and spatial water

  3. Liver and gallbladder cancer in immigrants to Sweden.

    Science.gov (United States)

    Hemminki, Kari; Mousavi, Seyed Mohsen; Brandt, Andreas; Ji, Jianguang; Sundquist, Jan

    2010-03-01

    The changes of cancer incidence upon immigration can be used as an estimator of environmental influence on cancer risk. We studied site-specific liver and biliary cancers in first-generation immigrants to Sweden with an aim to search for aetiological clues and to find evidence for indigenous incidence rates. We used the nation-wide Swedish Family-Cancer Database to calculate standardised incidence ratios (SIRs) in immigrants compared to native Swedes. A total of 1428 cancers were identified in immigrants whose median ages (years) at immigration were 27 for men and 26 for women and whose median diagnostic ages were 64 and 66, respectively. The highest SIRs of 6.7 for primary liver cancer were observed for men from East Asia and sub-Saharan Africa. Increased SIRs were recorded for male immigrants from previous Yugoslavia (1.78), Southern Europe (2.91), Turkey (2.15) and Asian Arab countries (2.89). For gallbladder cancer, only women from the Indian subcontinent (3.84) and Chile (2.34) had increased risk while some Northern European immigrants showed decreased risks. Primary liver cancer was increased in immigrants from endemic regions of hepatitis B virus infection but also from large regions lacking cancer incidence data, North Africa, Asian Arab countries, Turkey and previous Yugoslavia; these are probably intermediary risk regions for this infection. The consideration of these regions as risk areas would justify active diagnostic and vaccination programs. The increase in gallbladder cancer in Chileans and Indians suggests that some persistent damage was inflicted before emigration, characterisation of which will be a challenge for aetiological studies. Copyright 2009 Elsevier Ltd. All rights reserved.

  4. New Forms of Youth Participation and Work in Sweden.

    Science.gov (United States)

    Hartmann, Jurgen

    1985-01-01

    Surveys past and current youth employment and social participation programs in Sweden. Maintains that while these were effective in giving Sweden one of the lowest youth unemployment rates among market-economy nations, more must be done to ensure meaningful social participation of youth in the community. (JDH)

  5. Occupational doses and ALARA - recent developments in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Godas, T.; Viktorsson, C. [Swedish Radiation Protection Institute, Stockholm (Sweden)

    1995-03-01

    Sweden has traditionally experienced very slow doses to workers in the nuclear industry. However, this trend has since last year been broken mainly due to significant maintenance and repair work. This paper will describe occupational dose trends in Sweden and discuss actions that are being implemented to control this new situation.

  6. A comparison of pedigree- and DNA-based measures for identifying inbreeding depression in the critically endangered Attwater's Prairie-chicken.

    Science.gov (United States)

    Hammerly, Susan C; Morrow, Michael E; Johnson, Jeff A

    2013-11-01

    The primary goal of captive breeding programmes for endangered species is to prevent extinction, a component of which includes the preservation of genetic diversity and avoidance of inbreeding. This is typically accomplished by minimizing mean kinship in the population, thereby maintaining equal representation of the genetic founders used to initiate the captive population. If errors in the pedigree do exist, such an approach becomes less effective for minimizing inbreeding depression. In this study, both pedigree- and DNA-based methods were used to assess whether inbreeding depression existed in the captive population of the critically endangered Attwater's Prairie-chicken (Tympanuchus cupido attwateri), a subspecies of prairie grouse that has experienced a significant decline in abundance and concurrent reduction in neutral genetic diversity. When examining the captive population for signs of inbreeding, variation in pedigree-based inbreeding coefficients (f(pedigree)) was less than that obtained from DNA-based methods (f(DNA)). Mortality of chicks and adults in captivity were also positively correlated with parental relatedness (r(DNA)) and f(DNA), respectively, while no correlation was observed with pedigree-based measures when controlling for additional variables such as age, breeding facility, gender and captive/release status. Further, individual homozygosity by loci (HL) and parental rDNA values were positively correlated with adult mortality in captivity and the occurrence of a lethal congenital defect in chicks, respectively, suggesting that inbreeding may be a contributing factor increasing the frequency of this condition among Attwater's Prairie-chickens. This study highlights the importance of using DNA-based methods to better inform management decisions when pedigrees are incomplete or errors may exist due to uncertainty in pairings. © 2013 John Wiley & Sons Ltd.

  7. General equilibrium effects of increasing carbon taxes in Sweden

    International Nuclear Information System (INIS)

    Harrison, G.W.; Kristroem, B.

    1997-01-01

    Sweden was one of the first countries to introduce carbon taxes, and is currently evaluating further carbon taxes. The authors were asked to advise a government commission charged with undertaking the official Swedish evaluation. We did so by constructing and simulating a computable general equilibrium model of Sweden. In this report, the carbon tax debate in Sweden is first reviewed, then our model is described and the main results presented. The conclusion from the cost-benefit analysis is clear, the benefits of increasing the carbon tax in Sweden are a tiny fraction of the costs that consumers must pay in the form of higher prices and reduced incomes. Although we do not put much credence in the gross benefit numbers, they do serve to highlight the basis of our conclusion that carbon tax increases are not currently justifiable in Sweden. 35 refs., 13 tabs

  8. General equilibrium effects of increasing carbon taxes in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Harrison, G W [South Carolina Univ., Columbia, SC (United States). Dept. of Economics, College of Business Administration; Kristroem, B [Swedish Univ. of Agricultural Sciences, Umeaa (Sweden). Dept. of Forest Economics

    1997-09-01

    Sweden was one of the first countries to introduce carbon taxes, and is currently evaluating further carbon taxes. The authors were asked to advise a government commission charged with undertaking the official Swedish evaluation. We did so by constructing and simulating a computable general equilibrium model of Sweden. In this report, the carbon tax debate in Sweden is first reviewed, then our model is described and the main results presented. The conclusion from the cost-benefit analysis is clear, the benefits of increasing the carbon tax in Sweden are a tiny fraction of the costs that consumers must pay in the form of higher prices and reduced incomes. Although we do not put much credence in the gross benefit numbers, they do serve to highlight the basis of our conclusion that carbon tax increases are not currently justifiable in Sweden. 35 refs., 13 tabs.

  9. Biomass burning in eastern Europe during spring 2006 caused high deposition of ammonium in northern Fennoscandia

    DEFF Research Database (Denmark)

    Karlsson, Per Erik; Ferm, Martin; Pihl Karlsson, Gunilla

    2013-01-01

    High air concentrations of ammonium were detected at low and high altitude sites in Sweden, Finland and Norway during the spring 2006, coinciding with polluted air from biomass burning in eastern Europe passing over central and northern Fennoscandia. Unusually high values for throughfall deposition...... of ammonium were detected at one low altitude site and several high altitude sites in north Sweden. The occurrence of the high ammonium in throughfall differed between the summer months 2006, most likely related to the timing of precipitation events. The ammonia dry deposition may have contributed to unusual...... visible injuries on the tree vegetation in northern Fennoscandia that occurred during 2006, in combination with high ozone concentrations. It is concluded that long-range transport of ammonium from large-scale biomass burning may contribute substantially to the nitrogen load at northern latitudes. © 2013...

  10. Climate impact from peat utilisation in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Uppenberg, S.; Zetterberg, L.; Aahman, M.

    2001-08-01

    The climate impact from the use of peat for energy production in Sweden has been evaluated in terms of contribution to atmospheric radiative forcing. This was done by attempting to answer the question 'What will be the climate impact if one would use 1 m{sup 2} of mire for peat extraction during 20 years?'. Two different methods of after-treatment were studied: afforestation and restoration of wetland. The climate impact from a peatland - wetland energy scenario and a peatland - forestry energy scenario was compared to the climate impact from coal, natural gas and forest residues. Sensitivity analyses were performed to evaluate which parameters that are important to take into consideration in order to minimize the climate impact from peat utilisation.

  11. Documents and legal texts: Australia, Germany, Sweden

    International Nuclear Information System (INIS)

    Anon.

    2012-01-01

    Australia: National Radioactive Waste Management Act 2012 No. 29, 2012 (An Act to make provision in relation to the selection of a site for, and the establishment and operation of, a radioactive waste management facility, and for related purposes). Germany: Act on the Peaceful Utilisation of Atomic Energy and the Protection against its Hazards (Atomic Energy Act) of 23 December 1959, as amended and promulgated on 15 July 1985, last amendment by the Act of 8 November 2011. Sweden: The Swedish Radiation Safety Authority's regulations concerning clearance of materials, rooms, buildings and land in practices involving ionising radiation (Swedish Radiation Safety Authority Regulatory Code issued on 20 October 2011, Published on 2 November 2011); The Swedish Radiation Safety Authority's general advice on the application of the regulations concerning clearance of materials, rooms, buildings and land in practices involving ionising radiation (issued on 20 October 2011)

  12. Time trends in human fecundability in Sweden

    DEFF Research Database (Denmark)

    Scheike, Thomas H; Rylander, Lars; Carstensen, Lisbeth

    2008-01-01

    ,000 primiparous women 20 years of age and older in the nationwide Swedish Medical Birth Registry from 1983 through 2002. This age restriction led to an exclusion of 10% of primiparous pregnancies. Subfertility (TTP > or =1 year) was analyzed as a function of maternal age, calendar time at initiation of attempt...... increased with age, except that for women in their late 1930s, an apparent decrease was observed, particularly among the early cohorts. CONCLUSION: We found decreasing subfertility over time. We speculate that these patterns might be related to a Sweden-specific decrease over time in sexually transmitted...... diseases, to changes in sexual behavior induced by socioeconomic conditions, or to broader biologic or educational trends....

  13. Reprocessing in Sweden: History and perspective

    International Nuclear Information System (INIS)

    Hultgren, Aa.; Oesterlund, C.G.

    1990-10-01

    Against the background of nuclear power development and installation in Sweden an overview is presented of the parallel domestic development of the reprocessing of spent nuclear fuel. The original selection of the natural uranium - heavy water reactor in the 1950s included spent fuel reprocessing and recycle, and process and plant studies were performed to that end. The switch to light water reactors in the 1960s did not change the planning to recycle; however, the participation in the Eurochemic undertaking, and the delay in the nuclear programme stopped further domestic development work. A number of governmental committee investigations in the 1970s on the radioactive waste issue and, above all, the decision to phase out nuclear power by 2010, after a referendum following the TMI-accident, finally resulted in a decision to plan only for direct disposal of spent nuclear fuel. This policy still prevails. (42 refs.)

  14. Media use in distance education in Sweden

    Directory of Open Access Journals (Sweden)

    Norman F. Davies

    2013-02-01

    Full Text Available This article gives an overview of distance language teaching which developed rapidly in Sweden after the Second World War. It argues that so far little use has been made of technical aids and that the computer as such is still a stranger both to the language teacher and the student. The writer concludes that perhaps the time has come for a technical revolution amongst Arts students. Met hierdie artikel word 'n oorsig gegee oor afstandsonderrig-spesifiek wat tale betref-soos dit in Swede ontwikkel het na die Tweede Wereldoorlog. Daar word op gewys dat tot dusver min gebruik gemaak is van tegniese hulpmiddels en dat vera! die rekenaar onderbenut is. Die skrywer sluit met die gedagte dat die tyd moontlik ryp is vir 'n tegnologiese rewolusie"in die geledere van die Lettere en Wysbegeerte.

  15. Selling eugenics: the case of Sweden.

    Science.gov (United States)

    Bjorkman, Maria; Widmalm, Sven

    2010-12-20

    This paper traces the early (1910s to 1920s) development of Swedish eugenics through a study of the social network that promoted it. The eugenics network consisted mainly of academics from a variety of disciplines, but with medicine and biology dominating; connections with German scientists who would later shape Nazi biopolitics were strong. The paper shows how the network used political lobbying (for example, using contacts with academically accomplished MPs) and various media strategies to gain scientific and political support for their cause, where a major goal was the creation of a eugenics institute (which opened in 1922). It also outlines the eugenic vision of the institute's first director, Herman Lundborg. In effect the network, and in particular Lundborg, promoted the view that politics should be guided by eugenics and by a genetically superior elite. The selling of eugenics in Sweden is an example of the co-production of science and social order.

  16. Climate impact from peat utilisation in Sweden

    International Nuclear Information System (INIS)

    Uppenberg, S.; Zetterberg, L.; Aahman, M.

    2001-08-01

    The climate impact from the use of peat for energy production in Sweden has been evaluated in terms of contribution to atmospheric radiative forcing. This was done by attempting to answer the question 'What will be the climate impact if one would use 1 m 2 of mire for peat extraction during 20 years?'. Two different methods of after-treatment were studied: afforestation and restoration of wetland. The climate impact from a peatland - wetland energy scenario and a peatland - forestry energy scenario was compared to the climate impact from coal, natural gas and forest residues. Sensitivity analyses were performed to evaluate which parameters that are important to take into consideration in order to minimize the climate impact from peat utilisation

  17. Landscape Epidemiology of Tularemia Outbreaks in Sweden

    Science.gov (United States)

    Svensson, Kerstin; Bäck, Erik; Eliasson, Henrik; Berglund, Lennart; Granberg, Malin; Karlsson, Linda; Larsson, Pär; Forsman, Mats

    2009-01-01

    Summer outbreaks of tularemia that occurred from 1995 through 2005 in 2 locations in Sweden affected 441 persons. We performed an epidemiologic investigation of these outbreaks using a novel strategy, involving high-resolution genotyping of Francisella tularensis isolates obtained from 136 patients (using 18 genetic markers developed from 6 F. tularensis genome sequences) and interviews with the patients. Strong spatial associations were found between F. tularensis subpopulations and the places of disease transmission; infection by some subpopulations occurred within areas as small as 2 km2, indicating unidentified environmental point sources of tularemia. In both locations, disease clusters were associated with recreational areas beside water, and genetic subpopulations were present throughout the tularemia season and persisted over years. High-resolution genotyping in combination with patients’ statements about geographic places of disease transmission provided valuable indications of likely sources of infection and the causal genotypes during these tularemia outbreaks. PMID:19961673

  18. Physical protection philosophy and techniques in Sweden

    International Nuclear Information System (INIS)

    Dufva, B.

    1988-01-01

    The circumstances for the protection of nuclear power plants are special in Sweden. A very important factor is that armed guards at the facilities are alien to the Swedish society. They do not use them. The Swedish concept of physical protection accepts that the aggressor will get into the facility. With this in mind, the Swedish Nuclear Power Inspectorate (SKI) has established the policy that administrative, technical, and organizational measures will be directed toward preventing an aggressor from damaging the reactor, even if he has occupied the facility. In addition, the best conditions possible shall be established for the operator and the police to reoccupy the plant. The author believes this policy is different from that of many other countries. Therefore, he focusses on the Swedish philosophy and techniques for the physical protection of nuclear power plants

  19. Wind Power Statistics Sweden 2009; Vindkraftstatistik 2009

    Energy Technology Data Exchange (ETDEWEB)

    2010-04-15

    In 2009, wind power produced 2.5 TWh, an increase of 26 percent over the previous year. Throughout the period 2003-2009 has production of electricity from wind power almost quadrupled. Sweden's total net production of electricity amounted, according to provisional statistics for 2009, to 133.7 TWh. The year 2007 wind energy's share passed 1.0 percent of total net production of electricity for the first time. In 2008 the proportion was 1.4 percent, and in 2009 to almost 1.9 percent of total net production. Total installed power 2009 was 1448 MW and the number of plants was 1359, an inckW{sub pse} with 363 MW and 198 resp. from 2008. In 2009, there were three main support system for wind power in Sweden: the certificate system; the wind pilot project; and the environmental bonus. The electricity certificate system is a market-based support system for electricity generation from renewables which includes wind power as one of the approved techniques. The system was introduced in 2003 and aims to increase the production of electricity from renewable energy sources by 25 TWh from 2002 levels by 2020.. Wind pilot support is a support to the market for large-scale wind power. Support aims to reduce the cost of the creation of new wind energy and promoting new technologies. Wind Pilot Aid, which has existed since 2003, has been extended until in 2012 and has increased by 350 million SEK (about 36 M Euro) for the period 2008-2012. The environmental bonus, which means a tax subsidy, has been stepped down for each year until and by the year 2009, which was the last year. In 2009, environmental bonus was 0.12 SEK/kWh for electricity from offshore wind. For onshore wind power the environmentally bonus ceased in 2008

  20. Osmium in environmental samples from Northeast Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Rodushkin, Ilia [Division of Applied Geology, Lulea University of Technology, S-971 87 Lulea (Sweden); ALS Laboratory Group, ALS Analytica AB, Aurorum 10, S-977 75 Lulea (Sweden)], E-mail: ilia.rodushkin@alsglobal.com; Engstroem, Emma [Division of Applied Geology, Lulea University of Technology, S-971 87 Lulea (Sweden); Soerlin, Dieke; Ponter, Christer; Baxter, Douglas C. [ALS Laboratory Group, ALS Analytica AB, Aurorum 10, S-977 75 Lulea (Sweden)

    2007-11-01

    Osmium (Os) concentrations and {sup 187}Os/{sup 188}Os isotope abundance ratios are presented for sedimentary materials, soils, humus, plants, mushrooms, mosses and lichens collected in the vicinity of the town of Lulea, Northeast Sweden, the data for biological specimens being the first reported. Contributions from sampling and varying exposure time to the observed environmental variability were evaluated. Sedimentary materials (from both fresh and brackish water) are most elevated in radiogenic {sup 187}Os, followed by inorganic soil horizons, mushrooms and humus. The Os isotopic compositions of plants, mosses and lichens are much less radiogenic, with mean {sup 187}Os/{sup 188}Os lying within a relatively narrow 0.3-0.6 range. Significant temporal variations in Os concentrations and isotopic compositions of plant samples are attributed to integrative uptake of airborne Os with non-radiogenic composition. Measured Os concentrations in biological matrices increase in the order: small shrub leaves (blueberry and lingonberry) {<=} spruce needles {<=} mushrooms {<=} tree leaves {<=} pine needles < mosses << lichens. The concentrations found in three different species of plant were used to provide the first estimates of gaseous osmium tetroxide (OsO{sub 4}) in the environment. Though the Os content of samples from Northeast Sweden does not differ significantly from matrix-matched international reference materials (not certified for Os) of abiotic origin, the estimates of gaseous OsO{sub 4} concentrations are roughly an order of magnitude higher than have been reported for particle-bound Os in other studies. The pronounced spatial variations between relatively closely situated sites in mean {sup 187}Os/{sup 188}Os ratios for samples of the same species (presumably with the same dominating uptake mechanism) point to the presence of different local Os sources. This study therefore demonstrates that emissions of Os from automobile catalytic converters are not the only

  1. Osmium in environmental samples from Northeast Sweden

    International Nuclear Information System (INIS)

    Rodushkin, Ilia; Engstroem, Emma; Soerlin, Dieke; Ponter, Christer; Baxter, Douglas C.

    2007-01-01

    Osmium (Os) concentrations and 187 Os/ 188 Os isotope abundance ratios are presented for sedimentary materials, soils, humus, plants, mushrooms, mosses and lichens collected in the vicinity of the town of Lulea, Northeast Sweden, the data for biological specimens being the first reported. Contributions from sampling and varying exposure time to the observed environmental variability were evaluated. Sedimentary materials (from both fresh and brackish water) are most elevated in radiogenic 187 Os, followed by inorganic soil horizons, mushrooms and humus. The Os isotopic compositions of plants, mosses and lichens are much less radiogenic, with mean 187 Os/ 188 Os lying within a relatively narrow 0.3-0.6 range. Significant temporal variations in Os concentrations and isotopic compositions of plant samples are attributed to integrative uptake of airborne Os with non-radiogenic composition. Measured Os concentrations in biological matrices increase in the order: small shrub leaves (blueberry and lingonberry) ≤ spruce needles ≤ mushrooms ≤ tree leaves ≤ pine needles 4 ) in the environment. Though the Os content of samples from Northeast Sweden does not differ significantly from matrix-matched international reference materials (not certified for Os) of abiotic origin, the estimates of gaseous OsO 4 concentrations are roughly an order of magnitude higher than have been reported for particle-bound Os in other studies. The pronounced spatial variations between relatively closely situated sites in mean 187 Os/ 188 Os ratios for samples of the same species (presumably with the same dominating uptake mechanism) point to the presence of different local Os sources. This study therefore demonstrates that emissions of Os from automobile catalytic converters are not the only source of contemporary environmental contamination

  2. Trends in air concentration and deposition at background monitoring sites in Sweden - major inorganic compounds, heavy metals and ozone

    Energy Technology Data Exchange (ETDEWEB)

    Kindbom, K.; Svensson, Annika; Sjoeberg, K.; Pihl Karlsson, G.

    2001-09-01

    This report describes concentrations in air of sulphur compounds, soot, nitrogen compounds and ozone in Sweden between 1985-1998. Time trends of concentration in precipitation and deposition of sulphate, nitrate, ammonium, acidity, base cations and chloride in six different regions covering Sweden are evaluated during the period 1983-1998. Trends of heavy metals in precipitation have been analysed for the period 1983-1998 and the change in heavy metal concentration, 1975-1995, in mosses is described. Data used in the trend analyses originates from measurements performed at six Swedish EMEP stations and from approximately 25 stations within the national Precipitation Chemistry Network. Two different statistical methods, linear regression and the non-parametric Mann Kendall test, have been used to evaluate changes in annual mean values. Time trends of concentration of sulphur dioxide, particulate sulphate, soot, nitrogen dioxide, total nitrate and total ammonium in air show highly significant decreasing trends, except for soot at one station in northern Sweden. Concentrations of ozone have a strong seasonal variation with a peak occurring in spring every year. However, annual ozone concentrations show no obvious trends in spite of decreasing emissions of the precursors NOx and VOC. A slight indication of a decreasing trend in the number of ozone episodes might be seen from 1990 to 1998. Sulphate concentrations in precipitation and deposition show strongly significant decreasing trends in the whole country. Concentrations and deposition of nitrate and ammonium have been decreasing in all areas except for nitrate at stations in south-west and north-west Sweden and ammonium in south-west Sweden. Acidity has decreased in all areas since 1989, resulting in increasing pH values in Sweden. The interannual variations of concentration and deposition of base cations and chloride are large and few general trends can be seen during 1983-1997. Time trends of four heavy metals in

  3. Temporal and spatial trends for trace metals in streams and rivers across Sweden (1996–2009

    Directory of Open Access Journals (Sweden)

    J. Fölster

    2011-07-01

    Full Text Available Long term data series (1996 through 2009 for trace metals were analyzed from a large number of streams and rivers across Sweden varying in tributary watershed size from 0.05 to 48 193 km2. The final data set included 139 stream sites with data for arsenic (As, cobalt (Co, copper (Cu, chromium (Cr, nickel (Ni, lead (Pb, zinc (Zn, and vanadium (V. Between 7 % and 46 % of the sites analyzed showed significant trends according to the seasonal Kendall test. However, in contrast to previous studies and depositional patterns, a substantial portion of the trends were positive, especially for V (100 %, As (95 %, and Pb (68 %. Other metals (Zn and Cr generally decreased, were mixed (Ni and Zn, or had very few trends (Co over the study period. Trends by region were also analyzed and some showed significant variation between the north and south of Sweden. Regional trends for both Cu and Pb were positive (60 % and 93 %, respectively in the southern region but strongly negative (93 % and 75 %, respectively in the northern region. Kendall's τ coefficients were used to determine dependence between metals and potential in-stream drivers including total organic carbon (TOC, iron (Fe, pH, and sulphate (SO42−. TOC and Fe correlated positively and strongly with As, V, Pb, and Co while pH and SO42− generally correlated weakly, or not at all with the metals studied.

  4. Hearths in the coastal areas of northernmost Sweden, from the period AD 800 to 1950

    Directory of Open Access Journals (Sweden)

    Lars Liedgren

    2016-08-01

    Full Text Available This paper presents a study of the chronological setting of hearths registered in FMIS (digital register containing records of all known ancient monuments in Sweden in the provinces of Västerbotten and Norrbotten, Northern Sweden. A total of c. 1500 hearths are known in the area, mainly situated north of the river Skellefteälven. Within a study area of 107 x 94 km, 32 hearths were randomly selected for excavation, each site embracing 1-14 hearths. The sites were scanned using a metal detector and nearly all artifacts found were from the period AD 1600-1900. 14C-datings of charcoal and burned bones corroborated that most hearths were used during this period, with a large number dating to the 19th and 20th centuries. Many hearths contained bones from mature reindeer, indicating that the hearths were related to reindeer herding. We suggest that most hearths are related to nomadic Sami reindeer herders using coastal areas for winter pasture, possibly resulting from the breakdown of the “lappskatteland” (taxation lands system and an increase in reindeer numbers.

  5. Mercury in fur of Daubenton's bat (Myotis daubentonii) in Southern Sweden and Comparison to Ecotoxicological Thresholds.

    Science.gov (United States)

    Åkerblom, Staffan; de Jong, Johnny

    2017-11-01

    To characterise mercury (Hg) exposure in Daubenton's bat (Myotis daubentonii, Kuhl 1817) in southern Sweden, 17 specimens were captured in 2013 and back fur samples were taken for analysis to determine Hg concentrations. The fur Hg levels determined [1.15 ± 0.27 (mean ± standard deviation, n = 17) µg Hg g -1 fresh weight (fw)] represent a baseline for comparison in future assessments of Hg exposure in bat populations in northern Europe. Mercury concentrations were close to those reported in fur from other bat species, but were lower than proposed toxicological thresholds in bats (> 30 µg Hg g -1  fw) and mice (5 µg Hg g -1  fw). This is the first study to examine Hg exposure in bats in Scandinavia.

  6. The Autumn Ghost : the history of polioepidemics in Sweden

    OpenAIRE

    Axelsson, Per

    2004-01-01

    Polio epidemics appeared in Sweden in 1881 and at the turn of the 20th century the disease became an annual feature in the epidemiological pattern. Due to vaccination starting in 1957 epidemics ceased to exist in Sweden around 1965. This thesis deals with the history polio epidemics in Sweden, 1880-1965 and studies the demographical influence of polio, how the medical authorities investigated and tried to combat it, and the care of those who contracted the disease. A study of polio mortality ...

  7. Annual Report 1999. Electric power in Sweden

    International Nuclear Information System (INIS)

    2000-07-01

    Power Association is of the opinion that the increase in production taxes on nuclear power is completely misdirected. Sweden is the only EU country to have production taxes on electricity. Uncertainty and the lack of stability in the present taxation system will entail considerable difficulties both for electricity-intensive industry and for the power companies vis-a-vis long-term investment in Sweden. In 1999, overall consumption in the country fell by 0.3 TWh to 142.9 TWh, compared with last year. The decrease is explained by the fact that the autumn was very warm. Inflow into the major rivers was somewhat higher than normal enabling 70.4 TWh to be generated by the hydropower plants. This is 6 TWh more than during a normal year. Nuclear power accounted for 70.2 TWh, equal to the previous year. Additionally, combined heat and power and condensing plants accounted for 9.5 TWh, almost half of which using biofuels. Wind power continues to increase. At year-end, there were about 480 wind power plants, and the annual production was 0.4 TWh. Overall electricity production in the country was 150.5 TWh, a decrease of 3.4 TWh, or just under three percent. Exports amounted to 16.1 TWh and imports to 8.5 TWh. The average price for the year on the Nordic power exchange's spot market (Sector Sweden) was SEK 0.119 per kWh. The low price is explained by the mild weather and a plentiful supply of water in the Nordic reservoirs. On 1 November, the electricity market was changed in such a way that small consumers, with a fuse rating of up to 200 amps, were also able to take part. Parliament's decision to remove the requirement for continually registering hourly meters was of crucial importance. With this measure, the electricity market was also opened up to household customers. Hourly metering was replaced by profile settlement. Customers were offered fixed prices that could be considerably lower than previously. Flexible prices were on offer, e.g. linked to the power exchange's spot

  8. Novel mutations in CRB1 gene identified in a chinese pedigree with retinitis pigmentosa by targeted capture and next generation sequencing

    Science.gov (United States)

    Lo, David; Weng, Jingning; Liu, xiaohong; Yang, Juhua; He, Fen; Wang, Yun; Liu, Xuyang

    2016-01-01

    PURPOSE To detect the disease-causing gene in a Chinese pedigree with autosomal-recessive retinitis pigmentosa (ARRP). METHODS All subjects in this family underwent a complete ophthalmic examination. Targeted-capture next generation sequencing (NGS) was performed on the proband to detect variants. All variants were verified in the remaining family members by PCR amplification and Sanger sequencing. RESULTS All the affected subjects in this pedigree were diagnosed with retinitis pigmentosa (RP). The compound heterozygous c.138delA (p.Asp47IlefsX24) and c.1841G>T (p.Gly614Val) mutations in the Crumbs homolog 1 (CRB1) gene were identified in all the affected patients but not in the unaffected individuals in this family. These mutations were inherited from their parents, respectively. CONCLUSION The novel compound heterozygous mutations in CRB1 were identified in a Chinese pedigree with ARRP using targeted-capture next generation sequencing. After evaluating the significant heredity and impaired protein function, the compound heterozygous c.138delA (p.Asp47IlefsX24) and c.1841G>T (p.Gly614Val) mutations are the causal genes of early onset ARRP in this pedigree. To the best of our knowledge, there is no previous report regarding the compound mutations. PMID:27806333

  9. 26 CFR 1.1291-1 - Taxation of U.S. persons that are shareholders of PFICs that are not pedigreed QEFs.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Taxation of U.S. persons that are shareholders of PFICs that are not pedigreed QEFs. 1.1291-1 Section 1.1291-1 Internal Revenue INTERNAL REVENUE... Determining Capital Gains and Losses § 1.1291-1 Taxation of U.S. persons that are shareholders of PFICs that...

  10. Dynamics of Timber Market Integration in Sweden

    Directory of Open Access Journals (Sweden)

    Vishal Chandr Jaunky

    2015-12-01

    Full Text Available This paper addresses the performance of the timber markets (Scots pine, Pinus silvestris L. and Norway spruce, Picea abies (L. Karst. by evaluating the order of market integration in three Swedish regions (Central, Northern, and Southern. Quarterly data of delivery prices are employed over the period 1999Q1–2012Q4. Various unit root and cointegration tests have been computed. The results indicate that the variables are integrated of first order and co-integrated, especially after controlling for structural breaks. This supports the law-of-one-price hypothesis (LOP. However, the effects of structural shocks on forestry are arguably significant and these are controlled for while performing a vector error-correction mechanism (VECM-based Granger-causality test. Bi-directional causality between the Northern and central markets is uncovered in the short-run. In the long-run, a similar causal effect is detected between Northern and Southern markets while the central market emerges as the price leader. Further investigation is carried out using variance decompositions and impulse response functions and these approaches also tend to confirm the existence of a single market well, as price interdependence between markets.

  11. Genomic-Enabled Prediction Based on Molecular Markers and Pedigree Using the Bayesian Linear Regression Package in R

    Directory of Open Access Journals (Sweden)

    Paulino Pérez

    2010-09-01

    Full Text Available The availability of dense molecular markers has made possible the use of genomic selection in plant and animal breeding. However, models for genomic selection pose several computational and statistical challenges and require specialized computer programs, not always available to the end user and not implemented in standard statistical software yet. The R-package BLR (Bayesian Linear Regression implements several statistical procedures (e.g., Bayesian Ridge Regression, Bayesian LASSO in a unified framework that allows including marker genotypes and pedigree data jointly. This article describes the classes of models implemented in the BLR package and illustrates their use through examples. Some challenges faced when applying genomic-enabled selection, such as model choice, evaluation of predictive ability through cross-validation, and choice of hyper-parameters, are also addressed.

  12. SNP Analysis and Whole Exome Sequencing: Their Application in the Analysis of a Consanguineous Pedigree Segregating Ataxia

    Directory of Open Access Journals (Sweden)

    Sarah L. Nickerson

    2015-10-01

    Full Text Available Autosomal recessive cerebellar ataxia encompasses a large and heterogeneous group of neurodegenerative disorders. We employed single nucleotide polymorphism (SNP analysis and whole exome sequencing to investigate a consanguineous Maori pedigree segregating ataxia. We identified a novel mutation in exon 10 of the SACS gene: c.7962T>G p.(Tyr2654*, establishing the diagnosis of autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS. Our findings expand both the genetic and phenotypic spectrum of this rare disorder, and highlight the value of high-density SNP analysis and whole exome sequencing as powerful and cost-effective tools in the diagnosis of genetically heterogeneous disorders such as the hereditary ataxias.

  13. Pedigree analysis of glucose-6 phosphate dehydrogenase (G6PD deficiency of a Javanese Chinese family in Indonesia

    Directory of Open Access Journals (Sweden)

    IDG Ugrasena

    2017-02-01

    Full Text Available The molecular and pedigree analyses in a Javanese Chinese family were carried oul on glucose-6-phosphate dehydrogenase deficiencies. By method of  MPTP scanning without the sequencing steps, those variants could be confirmed. Two out of three sons were clinically jaundiced at birth due to G6PD deficiency and identified to have a G to T nucleotide change al 1376th nucleotide 01 the G6PD gene (GI376T, corresponding to G6PD Canton. Another son was also identified to have a C to T nucleotide change at 1311st nucleotide 01 the G6PD gene (CI311T, corresponding to a Silent mutation. Their father was normal, but their mother obsorved to have the heleromutation 01 G1376T (G6PD Canton and C1311T (a Silent mutation.

  14. Lack of GNAQ and GNA11 germ-line mutations in familial melanoma pedigrees with uveal melanoma or blue nevi

    Directory of Open Access Journals (Sweden)

    Jason Ezra Hawkes

    2013-06-01

    Full Text Available Approximately 10% of melanoma cases are familial, but only 25-40% of familial melanoma cases can be attributed to germ-line mutations in the CDKN2A - the most significant high-risk melanoma susceptibility locus identified to date. The pathogenic mutation(s in most of the remaining familial melanoma pedigrees have not yet been identified. The most common mutations in nevi and sporadic melanoma are found in BRAF and NRAS, both of which result in constitutive activation of the MAPK pathway. However, these mutations are not found in uveal melanomas or the intradermal melanocytic proliferations known as blue nevi. Rather, multiple studies report a strong association between these lesions and somatic mutations in Guanine nucleotide-binding protein G(q subunit alpha (GNAQ, Guanine nucleotide-binding protein G(q subunit alpha-11 (GNA11 and BRCA1 associated protein-1 (BAP1. Recently, germ-line mutations in BAP1, the gene encoding a tumor suppressing deubiquitinating enzyme, have been associated with predisposition to a variety of cancers including uveal melanoma, but no studies have examined the association of germ-line mutations in GNAQ and GNA11 with uveal melanoma and blue nevi. We have now done so by sequencing exon 5 of both of these genes in 13 unique familial melanoma pedigrees, members of which have had either uveal or cutaneous melanoma and/or blue nevi. Germ-line DNA from a total of 22 individuals was used for sequencing; however no deleterious mutations were detected. Nevertheless, such candidate gene studies and the discovery of novel germ-line mutations associated with an increased MM susceptibility can lead to a better understanding of the pathways involved in melanocyte transformation, formulation of risk assessment, and the development of specific drug therapies.

  15. Genome scan of human systemic lupus erythematosus: Evidence for linkage on chromosome 1q in African-American pedigrees

    Science.gov (United States)

    Moser, Kathy L.; Neas, Barbara R.; Salmon, Jane E.; Yu, Hua; Gray-McGuire, Courtney; Asundi, Neeraj; Bruner, Gail R.; Fox, Jerome; Kelly, Jennifer; Henshall, Stephanie; Bacino, Debra; Dietz, Myron; Hogue, Robert; Koelsch, Gerald; Nightingale, Lydia; Shaver, Tim; Abdou, Nabih I.; Albert, Daniel A.; Carson, Craig; Petri, Michelle; Treadwell, Edward L.; James, Judith A.; Harley, John B.

    1998-01-01

    Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by production of autoantibodies against intracellular antigens including DNA, ribosomal P, Ro (SS-A), La (SS-B), and the spliceosome. Etiology is suspected to involve genetic and environmental factors. Evidence of genetic involvement includes: associations with HLA-DR3, HLA-DR2, Fcγ receptors (FcγR) IIA and IIIA, and hereditary complement component deficiencies, as well as familial aggregation, monozygotic twin concordance >20%, λs > 10, purported linkage at 1q41–42, and inbred mouse strains that consistently develop lupus. We have completed a genome scan in 94 extended multiplex pedigrees by using model-based linkage analysis. Potential [log10 of the odds for linkage (lod) > 2.0] SLE loci have been identified at chromosomes 1q41, 1q23, and 11q14–23 in African-Americans; 14q11, 4p15, 11q25, 2q32, 19q13, 6q26–27, and 12p12–11 in European-Americans; and 1q23, 13q32, 20q13, and 1q31 in all pedigrees combined. An effect for the FcγRIIA candidate polymorphism) at 1q23 (lod = 3.37 in African-Americans) is syntenic with linkage in a murine model of lupus. Sib-pair and multipoint nonparametric analyses also support linkage (P 2.0). Our results are consistent with the presumed complexity of genetic susceptibility to SLE and illustrate racial origin is likely to influence the specific nature of these genetic effects. PMID:9843982

  16. UHP metamorphism recorded by kyanite-bearing eclogite in the Seve Nappe Complex of northern Jämtland, Swedish Caledonides

    NARCIS (Netherlands)

    Janák, M.; Van Roermund, H.; Majka, J.; Gee, D.

    The first evidence for ultrahigh-pressure (UHP) metamorphism in the Seve Nappe Complex of the Scandinavian Caledonides is recorded by kyanite-bearing eclogite, found in a basic dyke within a garnet peridotite body exposed close to the lake Friningen in northern Jämtland (central Sweden). UHP

  17. The U.S. Financial Crisis: Lessons From Sweden

    National Research Council Canada - National Science Library

    Jackson, James K

    2008-01-01

    In the early 1990s, Sweden faced a banking and exchange rate crisis that led it to rescue banks that had experienced large losses on their balance sheets and that threatened a collapse of the banking system...

  18. Nuclear Liability and Insurance for Nuclear Damage in Sweden

    International Nuclear Information System (INIS)

    Thofelt, H.

    1998-01-01

    This paper contains some facts about the Swedish nuclear energy production system and about the nuclear operators liability with the important issues. The nuclear insurance of Sweden is also explained in short terms. (author)

  19. Distribution of TPM in Northern Europe.

    Science.gov (United States)

    Wängberg, Ingvar; Munthe, John; Ebinghaus, Ralf; Gårdfeldt, Katarina; Iverfeldt, Ake; Sommar, Jonas

    2003-03-20

    Total particulate mercury (TPM) in air has been measured during five 2-week campaigns at five measurement sites in Northern Europe. The measurements covered four seasons and the result constitutes a unique TPM data set from this region. Evidence for transport of TPM on a regional scale is reported as well as the historical trend of TPM in south of Sweden. All TPM measurements were made using a new mini particulate sampler. The device consists of a quartz fibre filter contained in a quarts glass filter holder and is a modified version of the MiniSamplr. This approach proves to be reliable and more cost efficient in comparison to alternative methods. Tests made to evaluate the performance of the sampler in terms of precision and comparability with sampling on Teflon membrane filters are also reported.

  20. The Adoption of Additive Manufacturing Technology in Sweden

    OpenAIRE

    Kianian, Babak; Tavassoli, Sam; Larsson, Tobias; Diegel, Olaf

    2015-01-01

    This article analyzes the adoption of additive manufacturing (AM) technologies in Sweden. The data set consists of a recent and representative sample of Swedish AM users (companies, universities, and research institutes). The authors investigate two questions. First, what are the current applications of AM in Sweden (e.g., rapid prototyping [RP], production)? Second, what are the factors that can explain the variation in AM adoption among the users? Using a regression analysis technique, the ...

  1. Energy policies of IEA countries: Sweden - 2008 review

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-05-15

    Sweden is one of the leading IEA countries in the use of renewable energy and has a long tradition of ambitious and successful policies to improve energy efficiency. Compared to the other IEA countries, Sweden's CO2 emissions per capita and per unit of GDP are low, partly owing to efficient and low-carbon space heating, and virtually carbon-free electricity generation. The country also remains a forerunner in electricity market liberalisation. Still, even if Sweden has continued to make progress in most areas of its energy policy since the IEA last conducted an in-depth review in 2004, there is room for improvement. As Sweden plans to further increase the use of renewable energy, it is crucial that these supplies are produced and used in the most sustainable manner for the environment and the economy as a whole. With regard to CO2 emissions, more can be done in all sectors, but as transport is the largest polluter and its emissions are increasing, it is the logical focus for Sweden's efforts to reduce emissions further. This is a significant challenge. Nuclear provides almost half of the electricity in Sweden, at a low cost and without CO2 emissions. But the future of nuclear power in the national power mix is still uncertain. To provide clear guidance to the electricity sector, Sweden will need to resolve the ambiguity about the future of nuclear power in the country. This review analyses the energy challenges facing Sweden and provides critiques and recommendations for further policy improvements. It is intended to provide input to Swedish energy policy makers to help them identify a path towards a more sustainable energy future.

  2. The health and working conditions of female immigrants in Sweden

    OpenAIRE

    Akhavan, Sharareh

    2006-01-01

    Sweden is one of the European countries that has gradually changed from a mainly ethnically homogeneous society into a multi-ethnic society. This change began in the late 1940s and has increased in pace, especially since the early 1960s. The overall aim of this thesis is to understand, describe and analyze the factors that contribute to poor health among female immigrants in Sweden, from the perspectives of class, gender and ethnicity. This thesis is based on four differ...

  3. Relative Deprivation and Sickness Absence in Sweden

    Directory of Open Access Journals (Sweden)

    Jonas Helgertz

    2013-08-01

    Full Text Available Background: A high prevalence of sickness absence in many countries, at a substantial societal cost, underlines the importance to understand its determining mechanisms. This study focuses on the link between relative deprivation and the probability of sickness absence. Methods: 184,000 men and women in Sweden were followed between 1982 and 2001. The sample consists of working individuals between the ages of 19 and 65. The outcome is defined as experiencing more than 14 days of sickness absence during a year. Based on the complete Swedish population, an individual’s degree of relative deprivation is measured through income compared to individuals of the same age, sex, educational level and type. In accounting for the possibility that sickness absence and socioeconomic status are determined by common factors, discrete-time duration models were estimated, accounting for unobserved heterogeneity through random effects. Results: The results confirm that the failure to account for the dynamics of the individual’s career biases the influence from socioeconomic characteristics. Results consistently suggest a major influence from relative deprivation, with a consistently lower risk of sickness absence among the highly educated. Conclusions: Altering individual’s health behavior through education appears more efficient in reducing the reliance on sickness absence, rather than redistributive policies.

  4. Relative deprivation and sickness absence in Sweden.

    Science.gov (United States)

    Helgertz, Jonas; Hess, Wolfgang; Scott, Kirk

    2013-08-29

    A high prevalence of sickness absence in many countries, at a substantial societal cost, underlines the importance to understand its determining mechanisms. This study focuses on the link between relative deprivation and the probability of sickness absence. 184,000 men and women in Sweden were followed between 1982 and 2001. The sample consists of working individuals between the ages of 19 and 65. The outcome is defined as experiencing more than 14 days of sickness absence during a year. Based on the complete Swedish population, an individual's degree of relative deprivation is measured through income compared to individuals of the same age, sex, educational level and type. In accounting for the possibility that sickness absence and socioeconomic status are determined by common factors, discrete-time duration models were estimated, accounting for unobserved heterogeneity through random effects. The results confirm that the failure to account for the dynamics of the individual's career biases the influence from socioeconomic characteristics. Results consistently suggest a major influence from relative deprivation, with a consistently lower risk of sickness absence among the highly educated. Altering individual's health behavior through education appears more efficient in reducing the reliance on sickness absence, rather than redistributive policies.

  5. Procurement of medical equipment in Sweden

    Directory of Open Access Journals (Sweden)

    Heikki Terio

    2010-02-01

    Full Text Available In many hospitals in Sweden the importance of technology management is already accepted and accepted since the hospital managements have recognised that technology is an integral part of all major policy and planning decisions. Today’s medical devices are technically complex and sometimes a system of interacting devices is required to achieve the desired clinical function. If the hospitals want to use the latest, modern technology, then they need to make substantial investments in both equipment and competence. Complex technology, large investments and need of highly qualii ed personnel to handle the medical devices are factors that indicate a need of well-dei ned procurement process as an essential part of the total health technology management system that should be used in a hospital. In such a procurement process, carefully prepared planning of technology investments can reduce the running costs and costs for maintenance substantially. In addition, a well-dei ned procurement process contributes to increase the patient safety. In Karolinska University Hospital goods and services are purchased for more than 20% of the hospital’s €1.2 billion turnover. It is therefore very important that the procurement is carried out ef ectively.

  6. File 'Energy-climate actions in Sweden'

    International Nuclear Information System (INIS)

    2009-01-01

    In a first part, this publication briefly presents some basic data and information on Sweden (geography, population, economy, administrative organisation, powers of local authorities, local finances), the Swedish 'energy profile' (consumption, intensity, imports and exports), greenhouse gas emissions (total and per sector), and the energy-climate strategy (impacts of climate change, national climatic strategy, national measures, action framework for local authorities). The second part addresses one of these action frameworks, the Klimatkommunernas network. It describes this network, its objectives, and possibilities for communities to join it. It describes its activities: information, publication of a strategic document of climate-energy actions for municipalities, examples of projects. The third part presents experiments performed by different local communities (Kristianstad, Vaexjoe, Malmoe, and Lund). For each of them are presented: the energy strategy (objectives, strategy, adaptation, energy-climate follow-up, application and actual measures), and some specific measures. These specific examples can be integrated systems based on biogas and biomass, a zero fossil fuel objective with the use of renewable energies for heat and cold production, for electricity production and to improve energy efficiency, to promote green fuels in transports, to reduce the impact of transports on climate, a sustainable town planning, environmental management. Some features are then highlighted in the adopted approach for these examples: a systemic, collaborative, participative and communicative approach

  7. Trends in nuclear power costs in Sweden

    International Nuclear Information System (INIS)

    Vesterhaugh, O.; Blomsnes, B.

    1979-01-01

    At the request of the Swedish Ministry of Industry, a study of the costs of nuclear power in Sweden was performed early this year. The main purpose of the study was to determine the real and projected costs of electricity produced by nuclear stations. The basis for the calculations of the study was the currently planned Swedish nuclear power programme consisting of 11 reactors of which six are operating, two waiting for start-up permission and the remainder are under construction. All cost components, relevant to the commercial programme were covered, with particular emphasis on future costs for handling of spent fuel, waste disposal and plant decommissioning. A capital depreciation time of 25 years and a 4 per cent effective annual interest rate (ie interest after correction for inflation) were assumed in the calculations given in December 1978 currency. The main result of the study is the average cost per kWh for the reactors. The results are in close agreement with the cost estimate given by the Swedish Energy Commission and now that the nuclear plants produce electricity considerably cheaper than other plants with the exception of some hydroelectric ones. (author)

  8. Projects on filter testing in Sweden

    International Nuclear Information System (INIS)

    Normann, B.; Wiktorsson, C.

    1985-01-01

    The Swedish nuclear power program comprises twelve light water reactors. Nine are boiling water reactors of ASEA-ATOM design and three are pressurized water reactors of Westinghouse design. Of these, ten are in operation and two are under construction and planned to go into operation during late 1984 and early 1985, respectively. Frequent tests on the penetration of particles through HEPA filters, regular tests on the adsorption of methyl iodide in the stand-by carbon filter units by laboratory testing are discussed. The proposed new regulations are based on many years of experience of filter system operation and of tests in-situ and in the laboratory. Moisture and water are factors that affect the functioning of filters. In addition, high loading of dust can give rise to increased penetration through HEPA filters, however pinholes could have less influence on the total penetration. Laboratory tests show that DOP particles retain 30-40% in 90 mm carbon filters (8-12 mesh). However no effect on the ability of carbon to adsorb methyl iodide after DOP contamination in combined carbon/HEPA filters has been observed. Leakage from ventilation ducts can cause radioactive contamination problems during filter testing with radioiodine. In-situ testing of control-room filters has been performed using inactive methyl iodide. A type of carbon bed not previously used in Sweden has been introduced. Testing of this filter type is discussed

  9. Reindeer pastoralism in Sweden 1550-1950

    Directory of Open Access Journals (Sweden)

    Lennart Lundmark

    2007-04-01

    Full Text Available In the middle of the 16th century we get the first opportunity to a more detailed knowledge of reindeerpastoralism in Sweden. At that time the Sami lived in a hunter-gatherer economy. A family had in average about 10-20 domesticated reindeer, mainly used for transport. They could also be milked and used as decoys when hunting wild reindeer. During late 16th century the Swedish state and merchants bought large amounts of fur from the Sami. The common payment was butter and flour. This created a new prosperity, which lead to a considerable increase in population in Swedish Lapland. The population became too large for a hunter-gatherer economy. A crisis in early 17th century was the starting point for the transition to a large-scale nomadic reindeer pastoralism. Up to the middle of the 18th century intensive reindeer pastoralism was successful. But the pastoralism became gradually too intensive and diseases started to spread when the herds were kept too densely crowded for milking in summertime. During the first decades of the 19th century reindeer pastoralism in Sweden went through a major crisis. The number of reindeer herding mountain-Sami decreased considerably, mainly because they went to live permanently along the Norwegian coastline. Intensive reindeer pastoralism started to give way for extensive herding towards the end of the 19th century. In the north of Sweden influences from the Kautokeino Sami were an important factor, in the south extensive reindeer herding started to expand when the market for meat came closer to the Sami. During the 1920s the milking of reindeer ceased in Sweden, except in a few families. At that time Sami families from the north had been removed southwards. They further demonstrated the superiority of extensive herding to the Sami in mid- and southern Lapland. Reindeer pastoralism is basically a system of interaction between man and animal, but it has been heavily influenced by market forces and state intervention

  10. Occupational balance in health professionals in Sweden.

    Science.gov (United States)

    Wagman, Petra; Lindmark, Ulrika; Rolander, Bo; Wåhlin, Charlotte; Håkansson, Carita

    2017-01-01

    Health care employees are often women, a group that has high degrees of sick leave and perhaps problems attaining occupational balance. However, people think differently about their everyday activities and it is therefore important to take their perceptions into account but occupational balance has not yet been measured in health professionals. The aim was to describe occupational balance in three different samples of health professionals in Sweden. A further aim was to investigate whether occupational therapists (OTs) rate their occupational balance differently from other health professionals. Four hundred and eighty-two health professionals, employees in public dentistry, mental health care and OTs, aged 21-70 years participated. The participants' occupational balance was measured using the occupational balance questionnaire (OBQ). The ratings of occupational balance were similar to earlier studies and did not differ significantly between the samples. The OTs' occupational balance was also similar to that of the other health professionals. The similarities in occupational balance indicate the same difficulties in attaining it. The result highlights the possibility that working people face similar difficulties in achieving occupational balance. Further research is warranted about how to attain it.

  11. Volcanic ash and daily mortality in Sweden after the Icelandic volcano eruption of May 2011.

    Science.gov (United States)

    Oudin, Anna; Carlsen, Hanne K; Forsberg, Bertil; Johansson, Christer

    2013-12-10

    In the aftermath of the Icelandic volcano Grimsvötn's eruption on 21 May 2011, volcanic ash reached Northern Europe. Elevated levels of ambient particles (PM) were registered in mid Sweden. The aim of the present study was to investigate if the Grimsvötn eruption had an effect on mortality in Sweden. Based on PM measurements at 16 sites across Sweden, data were classified into an ash exposed data set (Ash area) and an unexposed data set (No ash area). Data on daily all-cause mortality were obtained from Statistics Sweden for the time period 1 April through 31 July 2011. Mortality ratios were calculated as the ratio between the daily number of deaths in the Ash area and the No ash area. The exposure period was defined as the week following the days with elevated particle concentrations, namely 24 May through 31 May. The control period was defined as 1 April through 23 May and 1 June through 31 July. There was no absolute increase in mortality during the exposure period. However, during the exposure period the mean mortality ratio was 2.42 compared with 2.17 during the control period, implying a relatively higher number of deaths in the Ash area than in the No ash area. The differences in ratios were mostly due to a single day, 31 May, and were not statistically significant when tested with a Mann-Whitney non-parametric test (p > 0.3). The statistical power was low with only 8 days in the exposure period (24 May through 31 May). Assuming that the observed relative differences were not due to chance, the results would imply an increase of 128 deaths during the exposure period 24-31 May. If 31 May was excluded, the number of extra deaths was reduced to 20. The results of the present study are contradicting and inconclusive, but may indicate that all-cause mortality was increased by the ash-fall from the Grimsvötn eruption. Meta-analysis or pooled analysis of data from neighboring countries might make it possible to reach sufficient statistical power to study effects

  12. Volcanic Ash and Daily Mortality in Sweden after the Icelandic Volcano Eruption of May 2011

    Science.gov (United States)

    Oudin, Anna; Carlsen, Hanne K.; Forsberg, Bertil; Johansson, Christer

    2013-01-01

    In the aftermath of the Icelandic volcano Grimsvötn’s eruption on 21 May 2011, volcanic ash reached Northern Europe. Elevated levels of ambient particles (PM) were registered in mid Sweden. The aim of the present study was to investigate if the Grimsvötn eruption had an effect on mortality in Sweden. Based on PM measurements at 16 sites across Sweden, data were classified into an ash exposed data set (Ash area) and an unexposed data set (No ash area). Data on daily all-cause mortality were obtained from Statistics Sweden for the time period 1 April through 31 July 2011. Mortality ratios were calculated as the ratio between the daily number of deaths in the Ash area and the No ash area. The exposure period was defined as the week following the days with elevated particle concentrations, namely 24 May through 31 May. The control period was defined as 1 April through 23 May and 1 June through 31 July. There was no absolute increase in mortality during the exposure period. However, during the exposure period the mean mortality ratio was 2.42 compared with 2.17 during the control period, implying a relatively higher number of deaths in the Ash area than in the No ash area. The differences in ratios were mostly due to a single day, 31 May, and were not statistically significant when tested with a Mann-Whitney non-parametric test (p > 0.3). The statistical power was low with only 8 days in the exposure period (24 May through 31 May). Assuming that the observed relative differences were not due to chance, the results would imply an increase of 128 deaths during the exposure period 24–31 May. If 31 May was excluded, the number of extra deaths was reduced to 20. The results of the present study are contradicting and inconclusive, but may indicate that all-cause mortality was increased by the ash-fall from the Grimsvötn eruption. Meta-analysis or pooled analysis of data from neighboring countries might make it possible to reach sufficient statistical power to study

  13. IAEA Team Concludes Peer Review of Sweden's Nuclear Regulatory Framework, 17 February 2012, Stockholm, Sweden

    International Nuclear Information System (INIS)

    2012-01-01

    Full text: An international team of senior nuclear safety and radiation protection experts today concluded a 12-day mission to review the regulatory framework for nuclear and radiation safety in Sweden. The Integrated Regulatory Review Service (IRRS) mission, which was conducted at the request of Sweden, noted good practices in the country's nuclear regulatory system and also made recommendations and suggestions for the Swedish Radiation Safety Authority (SSM) and the government. These are aimed at strengthening the effectiveness of the country's regulatory framework and functions in line with IAEA Safety Standards. ''Throughout the mission, the IRRS team received full cooperation from SSM staff in its review of Sweden's regulatory, technical and policy issues,'' said Georg Schwarz, mission leader and Deputy Director General of the Swiss nuclear regulator (ENSI). 'The staff were open and candid in their discussions and provided the fullest practicable assistance', he commented. The main observations of the IRRS Review team included the following: SSM operates as an independent regulator in an open and transparent manner with well-organized regulatory processes; SSM is receptive to feedback and strives to maintain a culture of continuous learning; and Following the TEPCO Fukushima Daiichi accident, SSM responded promptly to public demand for information and communicated effectively with the national government, the public and other interested parties. Good practices identified by the IRRS team included, though they are not limited to, the following: The consolidation of the two previous national regulatory authorities into SSM was successful; Overall, SSM's management system is comprehensive and contributes to staff efficiency and effectiveness; The nuclear power plant refurbishment programme as required by SSM enhanced safety; and Sweden's regulatory framework for high-level waste disposal is comprehensive and technically sound. The IRRS Review team identified

  14. Sweden in the Delaware Valley: Everyday Life and Material Culture in New Sweden

    DEFF Research Database (Denmark)

    Naum, Magdalena; Ekengren, Fredrik; Zagal Mach Wolfe, Ulla Isabel

    2013-01-01

    In 1637 the Swedish Crown, encouraged by Dutch merchants, developed a plan to establish a colonial outpost in America to tap into profitable tobacco and beaver pelt trade. The same year the first cargo ships left Sweden and sailed westwards to claim their piece of America along the Delaware River......, their perception and interactions with the neighbouring Native American groups. It discusses the ways material culture was used, exchanged and appropriated by the colonists and the local Lenape and Susquehannock in the processes of meeting, negotiations and daily coexistence....

  15. Annual Report 1999. Electric power in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-15

    . The Swedish Power Association is of the opinion that the increase in production taxes on nuclear power is completely misdirected. Sweden is the only EU country to have production taxes on electricity. Uncertainty and the lack of stability in the present taxation system will entail considerable difficulties both for electricity-intensive industry and for the power companies vis-a-vis long-term investment in Sweden. In 1999, overall consumption in the country fell by 0.3 TWh to 142.9 TWh, compared with last year. The decrease is explained by the fact that the autumn was very warm. Inflow into the major rivers was somewhat higher than normal enabling 70.4 TWh to be generated by the hydropower plants. This is 6 TWh more than during a normal year. Nuclear power accounted for 70.2 TWh, equal to the previous year. Additionally, combined heat and power and condensing plants accounted for 9.5 TWh, almost half of which using biofuels. Wind power continues to increase. At year-end, there were about 480 wind power plants, and the annual production was 0.4 TWh. Overall electricity production in the country was 150.5 TWh, a decrease of 3.4 TWh, or just under three percent. Exports amounted to 16.1 TWh and imports to 8.5 TWh. The average price for the year on the Nordic power exchange's spot market (Sector Sweden) was SEK 0.119 per kWh. The low price is explained by the mild weather and a plentiful supply of water in the Nordic reservoirs. On 1 November, the electricity market was changed in such a way that small consumers, with a fuse rating of up to 200 amps, were also able to take part. Parliament's decision to remove the requirement for continually registering hourly meters was of crucial importance. With this measure, the electricity market was also opened up to household customers. Hourly metering was replaced by profile settlement. Customers were offered fixed prices that could be considerably lower than previously. Flexible prices were on offer, e.g. linked to the

  16. Sweden and the NEGP: A Pilot Study of the North European Gas Pipeline and Sweden's Dependence on Russian Energy

    Energy Technology Data Exchange (ETDEWEB)

    Larsson, Robert L.

    2006-06-15

    Developments between 2004 and 2006 indicate that a North European Gas Pipeline (NEGP) through the Baltic Sea, from Russia to Germany, may be realised in the coming decade. This would provide Europe with yet another opportunity to diversify its import channels of gas. It is however reasonable to assume that the NEGP also could change the strategic pattern and be a source of friction. The NEGP may rock the regional stability and reduce the potential of the new EU members to become security providers in Europe's northern dimension. It also gives increased leverage and influence to Russia, a state that has moved in an authoritarian direction under President Putin. The aim of this pilot study is to elucidate on the NEGP pipeline and Sweden's increasing dependence on Russian energy. A subsidiary aim is to outline a set of concerns that have bearing on the situation for the EU and Baltic Sea Region and that need to be further addressed. In conclusion, the NEGP will enhance Russia's direct leverage on Poland, Ukraine, and Belarus, as it will allow Russia to turn off gas supplies without affecting exports to other parts of Europe. Russia will also increase its leverage over the states that will or may be connected to the NEGP (Germany, and possibly Belgium, Denmark, the Netherlands and the UK). Even if Sweden is not embracing the NEGP, it is today highly sensitive as it imports most of its energy. It is increasingly dependent on Russian oil and is partly dependent on imports of electricity from Russia. Should the NEGP materialise and Sweden becomes connected in the future, it would likely be dependent also on natural gas. It is of paramount importance for the energy security of the connected states how the pipeline is constructed and operated. If there will be technical possibilities for Russia to tamper with the flow of gas to individual states without affecting supply to others, there are tangible threats to the importing states.

  17. Results of national lake surveys 1995 in Finland, Norway, Sweden, Denmark, Russian Kola, Russian Karelia, Scotland and Wales

    Energy Technology Data Exchange (ETDEWEB)

    Henriksen, Arne; Skjelkvaale, Brit Lisa [Norsk Inst. for Vannforskning, Oslo (Norway); Mannio, Jaakko [FEI, (Finland)] [and others

    1997-12-31

    Beginning in 1995, national lake surveys were conducted in the above North European countries. This report provides the first united evaluation of lake water chemistry in Northern Europe. It was found that, except for Denmark, the water was characterized by low ionic strength and had low content of nitrogen and phosphorus. In Finland, Norway, Sweden, Russian Kola and Karelia more than 50% of the lakes had low critical load (CL) values for sulphur acidity (S), while Scotland, Wales and Denmark had very few lakes with low CL for S. The highest percentage (27%) of lakes with exceedence of CL for S was found in Norway, while the values for Russian Kola, Sweden and Finland were 17%, 9% and 9%, respectively. In Scotland and Wales, critical loads for sulphur acidity were exceeded in 1% of the total lake population. For Denmark and Russian Karelia, too few lakes were sampled to give reliable estimates. This adds up to approximately 22000 lakes in Northern Europe where CL for S was exceeded. However, this number of lakes is a minimum as exceedence of CL for N was not included in the calculation due to lack of catchment data. 26 refs., 21 figs., 13 tabs.

  18. Generalization of heterogeneous alpine vegetation in air photo-based image classification, Latnjajaure catchment, northern Sweden

    Directory of Open Access Journals (Sweden)

    Lindblad, K. E. M.

    2006-12-01

    Full Text Available

    Mapping alpine vegetation at a meso-scale (catchment level using remote sensing presents difficulties due to a patchy distribution and heterogeneous spectral appearance of the plant cover. We discuss issues of generalization and accuracy assessment in this case study when using a digital CIR air photo for an automatic classification of the dominant plant communities. Spectral information from an aerial photograph was supplemented by classified plant communities in field and by topographical information derived from a DEM. 150 control points were tracked in the field using a GPS. The outcome from three alternative classifications was analysed by Kappa statistics, user’s and producer’s accuracy. Overall accuracy did not differ between the classifications although producer’s and user’s accuracy for separate classes differed together with total surface (ha and distribution. Manual accuracy assessment when recording the occurrence of the correct class within a radius of 5 meters from the control points generated an improvement of 16 % of the total accuracy. About 10 plant communities could be classified with acceptable accuracy where the chosen classification scheme determined the final outcome. If a high resolution pixel mosaic is generalized to units that match the positional accuracy of simple GPS this generalization may also influence the information content of the image.



    Hemos llevado a cabo la cartografía de la vegetación alpina a escala media (nivel de cuenca experimental mediante interpretación remota. Esta metodología plantea dificultades debido a la distribución en mosaico de la vegetación y a la heterogeneidad del espetro obtenido. Se discuten las posibilidades de generalización de los resultados y el grado de precisión alcanzado en este caso experimental mediante fotografía aérea digital CIR aplicada a una clasificación automática de las comunidades vegetales dominantes. La información espectral obtenida por foto áerea se complementó con la clasificación de las comunidades vegetales in situ y la información topográfica derivada de un Modelo Digital de Terreno. Además se marcaron 150 puntos de control en el campo por medio de GPS. Los resultados de tres clasificaciones alternativas se analizaron mediante el estadístico Kappa y la precisión del usuario y del productor. El grado de precisión obtenido apenas difirió entre clasificaciones, a pesar de que sí había diferencias significativas entre la precisión del usuario o del productor para las diferentes clases, así como para la superficie total y la distribución. La presencia sobre el terreno de una clase correctamente identificada a menos de 5 m de un punto de control, aumentó la precisión en un 16 %. Unas 10 comunidades vegetales pueden ser identificadas con un grado de precisión aceptable al terminar la clasificación. Si un mosaico de píxels de alta resolución se generaliza a unidades cuya precisión es comparable a la de un simple GPS, tal generalización puede también influir en la cantidad de información de la imagen.

  19. Radioactive disequilibria in mineralised drill core samples from the Bjoerklund uranium occurence, northern Sweden

    International Nuclear Information System (INIS)

    Smellie, J.A.T.

    1982-12-01

    Forming the basis of a pilot study to investigate the natural mobility of uranium and its daughter products within the geological environment, a series of six samples, chosen from two mineralised fracture zones at depths of 100-130m within a homogeneous leucocratic granite, were examined mineralogically and isotopically to establish the presence or absence of radioactive equilibrium that may indicate recent rock/water interaction processes (i.e. during the last 0.5 m.y.). The results show clear evidence of radioactive disequilibrium, and hence recent rock/water interaction, in four of the six samples. Some is attributable mostly to solution-solid 234 U recoil gain (weakly mineralised zones adjacent to the main mineralisation) and others to solid-solution 234 U recoil loss (moderate to highly mineralised zones). The richer type of impregnation mineralisation indicates apparent radioactive equilibrium. The absence of significant 238 U loss in the samples helps to underline the reducing conditions prevalent within open fracture systems at these depths. This has meant that uraninite, now found in fractured rock at about 100m depth, has been chemically stable in its environment for most, if not all, of its 1750 m.y. existence, including the last 0.5 m.y. when it has been closest to the atmosphere. This could indicate that spent nuclear fuel, which essentially is crystalline UO 2 , and comparable to uraninite once the main fission products have decayed, would also have been stable in this environment for similar periods of time. (Author)

  20. Lake Ecosystem Responses to Holocene Climate Change at the Subarctic Tree-Line in Northern Sweden

    DEFF Research Database (Denmark)

    Reuss, Nina Steenberg; Hammarlund, Dan; Rundgren, Mats

    2010-01-01

    sedimentary pigments, diatoms, chironomids, pollen, biogenic silica (BSi), carbon (C), nitrogen (N) elemental and stable-isotope records, and total lake-water organic carbon (TOC) concentration inferred from near-infrared spectroscopy (NIRS), suggest that the Holocene development of Lake Seukokjaure...

  1. Microbiota of an unpasteurised cellar-stored goat cheese from northern Sweden

    Directory of Open Access Journals (Sweden)

    Klara Båth

    2012-06-01

    Full Text Available This qualitative study reports on lactic acid bacteria (LAB, yeasts and moulds isolated from three artisanal Swedish cellar-stored goat cheeses aged for 1, 3 and 5 months. Starter culture LAB dominated in the younger cheeses, and Leuconostoc pseudomesenteroides, common in raw goats’ milk, had persisted from the unpasteurised milk into all the cheeses. Non-starter LAB dominated in the 5 month cheese, in particular, Lactobacillus sakei, a meat-associated LAB not previously isolated from cheese. Debaryomyces hansenii, and Penicillium and Mucor species were dominant among the yeasts and moulds, respectively. The cheese rind was not formed primarily from Penicillium species as in traditional cheeses such as Camembert – rather, mycelium from Mucor mucedo contributed to rind formation. Mould species known to produce sterigmatocystin, aflatoxins or ochratoxin A in cheese were not isolated in this study; growth of mycotoxigenic Aspergilli may have been inhibited by the cool conditions in the earth-cellar (4–6 °C.

  2. Process water geochemistry and interactions with magnetite at the Kiirunavaara iron mine, northern Sweden

    OpenAIRE

    Westerstrand, Magnus

    2013-01-01

    Current global estimates indicate that ca. 2400 million tonnes of iron is produced annually, most of which is used to make steel. Due to the associated costs, environmental challenges and energy consumption, steel is one of the world’s most intensively recycled materials. For example, about 98 % of structural steel is recycled in the USA. However, iron production is still increasing. Costs, prices and environmental demands have led to increased recycling, but also increased attention to the p...

  3. Soil map, area and volume calculations in Orrmyrberget catchment basin at Gideaa, Northern Sweden

    International Nuclear Information System (INIS)

    Ittner, T.; Tammela, P.T.; Gustafsson, E.

    1991-06-01

    Fallout studies in the Gideaa study site after the Chernobyl fallout in 1986, has come to the point that a more exact surface mapping of the studied catchment basin is needed. This surface mapping is mainly made for area calculations of different soil types within the study site. The mapping focus on the surface, as the study concerns fallout redistribution and it is extended to also include materials down to a depth of 0.5 meter. Volume calculations are made for the various soil materials within the top 0.5 m. These volume and area calculations will then be used in the modelling of the migration and redistribution of the fallout radionuclides within the studied catchment basin. (au)

  4. Metagenomic Analysis from the Interior of a Speleothem in Tjuv-Ante's Cave, Northern Sweden.

    Directory of Open Access Journals (Sweden)

    Marie Lisandra Zepeda Mendoza

    Full Text Available Speleothems are secondary mineral deposits normally formed by water supersaturated with calcium carbonate percolating into underground caves, and are often associated with low-nutrient and mostly non-phototrophic conditions. Tjuv-Ante's cave is a shallow-depth cave formed by the action of waves, with granite and dolerite as major components, and opal-A and calcite as part of the speleothems, making it a rare kind of cave. We generated two DNA shotgun sequencing metagenomic datasets from the interior of a speleothem from Tjuv-Ante's cave representing areas of old and relatively recent speleothem formation. We used these datasets to perform i an evaluation of the use of these speleothems as past biodiversity archives, ii functional and taxonomic profiling of the speleothem's different formation periods, and iii taxonomic comparison of the metagenomic results to previous microscopic analyses from a nearby speleothem of the same cave. Our analyses confirm the abundance of Actinobacteria and fungi as previously reported by microscopic analyses on this cave, however we also discovered a larger biodiversity. Interestingly, we identified photosynthetic genes, as well as genes related to iron and sulphur metabolism, suggesting the presence of chemoautotrophs. Furthermore, we identified taxa and functions related to biomineralization. However, we could not confidently establish the use of this type of speleothems as biological paleoarchives due to the potential leaching from the outside of the cave and the DNA damage that we propose has been caused by the fungal chemical etching.

  5. Solar forcing of climate during the last millennium recorded in lake sediments from northern Sweden

    DEFF Research Database (Denmark)

    Kokfelt, Ulla; Muscheler, Raimund

    2013-01-01

    century. Periods of low solar activity are associated with minima in minerogenic material and vice versa. A comparison between the sunspot cycle and a long instrumental series of summer precipitation further reveals a link between the 11-year solar cycle and summer precipitation variability since around...... 1960. Solar minima are in this period associated with minima in summer precipitation, whereas the amount of summer precipitation increases during periods with higher solar activity. Our results suggest that the climate responds to both the 11-year solar cycle and to long-term changes in solar activity...... and in particular solar minima, causing dry conditions with resulting decreased runoff....

  6. PLACE MARKETING AND RURAL MUNICIPALITIES IN NORTHERN SWEDEN: A CONTENT ANALYSIS OF MUNICIPAL HOMEPAGES

    OpenAIRE

    Olga Rauhut Kompaniets; Daniel Rauhut

    2013-01-01

    The place marketing concept is one of the most popular concepts used in the analysis and promotion of countries, regions, cities and towns. The intensification of competition for investment, tourism and human resources among European cities and towns has increased the importance of being unique. Most studies on place marketing focus on unique selling points and thus on brands of already extensively ‘marketed’ countries, national capitals and other large metropolitan areas, while the rural tow...

  7. The Place Marketing Concept of Rural Towns in Northern Sweden: What is the Unique Selling Point?

    OpenAIRE

    Kompaniets, Olga; Rauhut, Daniel

    2013-01-01

    The place marketing concept is one of the popular concepts to analyze and promote countries, regions, cities and towns. The intensification of competition for investment, tourism and human resources among European cities and towns has increased the importance of being unique. Consequently this has opened up the field for specialists in marketing and branding in terms of geographic, social, economic, political, cultural and historical and ethno-cultural development. Most of studies on place ma...

  8. Abdominal injuries in a low trauma volume hospital--a descriptive study from northern Sweden.

    Science.gov (United States)

    Pekkari, Patrik; Bylund, Per-Olof; Lindgren, Hans; Öman, Mikael

    2014-08-15

    Abdominal injuries occur relatively infrequently during trauma, and they rarely require surgical intervention. In this era of non-operative management of abdominal injuries, surgeons are seldom exposed to these patients. Consequently, surgeons may misinterpret the mechanism of injury, underestimate symptoms and radiologic findings, and delay definite treatment. Here, we determined the incidence, diagnosis, and treatment of traumatic abdominal injuries at our hospital to provide a basis for identifying potential hazards in non-operative management of patients with these injuries in a low trauma volume hospital. This retrospective study included prehospital and in-hospital assessments of 110 patients that received 147 abdominal injuries from an isolated abdominal trauma (n = 70 patients) or during multiple trauma (n = 40 patients). Patients were primarily treated at the University Hospital of Umeå from January 2000 to December 2009. The median New Injury Severity Score was 9 (range: 1-57) for 147 abdominal injuries. Most patients (94%) received computed tomography (CT), but only 38% of patients with multiple trauma were diagnosed with CT management succeeded in 82 patients. Surgery was performed for 28 patients, either immediately (n = 17) as result of operative management or later (n = 11), due to non-operative management failure; the latter mainly occurred with hollow viscus injuries. Patients with multiple abdominal injuries, whether associated with multiple trauma or an isolated abdominal trauma, had significantly more non-operative failures than patients with a single abdominal injury. One death occurred within 30 days. Non-operative management of patients with abdominal injuries, except for hollow viscus injuries, was highly successful in our low trauma volume hospital, even though surgeons receive low exposure to these patients. However, a growing proportion of surgeons lack experience in decision-making and performing trauma laparotomies. Quality assurance programmes must be emphasized to ensure future competence and quality of trauma care at low trauma volume hospitals.

  9. Significance of cold-season respiration and photosynthesis in a subarctic heath ecosystem in Northern Sweden

    DEFF Research Database (Denmark)

    Larsen, Klaus Steenberg; Ibrom, Andreas; Jonasson, S.

    2007-01-01

    While substantial cold-season respiration has been documented in most arctic and alpine ecosystems in recent years, the significance of cold-season photosynthesis in these biomes is still believed to be small. In a mesic, subartic heath during both the cold and warm season, we measured in situ...... ecosystem respiration and photosynthesis with a chamber technique at ambient conditions and at artificially, increased frequency of freeze-thaw (FT) cycles during fall and spring. We fitted the measured ecosystem exchange rates to respiration and photosynthesis models with R-2-values ranging from 0.81 to 0.......85. As expected, estimated cold-season (October, November, April and May) respiration was significant and accounted for at least 22% of the annual respiratory CO2 flux. More surprisingly, estimated photosynthesis during this period accounted for up to 19% of the annual gross CO2 uptake, suggesting that cold...

  10. Residential use of firewood in Northern Sweden and its influence on forest biomass resources

    OpenAIRE

    Lindroos, Ola

    2011-01-01

    Firewood is society’s oldest source of household energy and is still extensively used around the world. However, little is known about firewood usage in technologically advanced countries with high energy consumption. Some key issues include quantities of firewood currently used and future trends, as well as the influence of this usage on available biomass resources. This study addresses those issues through a postal questionnaire to 1500 of the firewood using households in a region in Northe...

  11. Effects of economic change on male morbidity in neighbouring industrial and rural municipalities in northern Sweden

    DEFF Research Database (Denmark)

    Diderichsen, Finn; Janlert, U

    1992-01-01

    The aim was to investigate the health effects of economic changes in a rural and industrial community.......The aim was to investigate the health effects of economic changes in a rural and industrial community....

  12. Geochemistry of Spodosols formed in holocene till, Norra Storfjaellet Massif, northern Sweden

    International Nuclear Information System (INIS)

    Earl-goulet, J.R.; Mahaney, W.C.; Milner, M.W.; Hancock, R.G.V.

    1997-01-01

    Silt and clay size fractions of soils, from a transect of six Spodosols formed in the Norra Storfjaellet Massif, were analyzed by neutron activation to determine the degree to which pedogenic processes have influenced the distribution of macro, micro and trace elements. The distributions of Mg, Ca and Fe, together with Co, Cr and other trace elements in the profiles, suggest the presence of different parent materials, with A and E horizons arising from an influx of aeolian sediment. Translocation processes, both physical and chemical, occurred in the soil concentrating Fe and Br in the spodic(Bs) horizons of the profiles. The rare earth elements (REEs) are predominantly associated with the heavy mineral fraction of the soil material. The distributions of chondrite normalized REEs patterns of the profiles indicate that light rare earth element (LREE) concentrations increase with horizon depth. The depletion of LREEs in the upper soil horizons confirms the presence of material that is chemically different from that in the lower horizons, thus indicating a distinct chemical difference from the local glacial deposits. (author)

  13. Disabled and Unmarried? Marital Chances Among Disabled People in Nineteenth-Century Northern Sweden

    Directory of Open Access Journals (Sweden)

    Helena Haage

    2017-04-01

    Full Text Available To marry and form a household of one’s own was the expected life course of most people in the nineteenth century, but little is known about whether individuals with disabilities shared the same demographic experience of marriage as non-disabled did. This study examines this issue by analyzing the marital chances of a group of disabled people—i.e. blind, deaf mute, crippled and with mental disabilities—compared with a non-disabled reference group. Our results show that about a quarter of the disabled individuals did marry, even though their marital propensities were significantly lower than those of non-disabled people. These propensities also differed by gender and type of disability. We suggest that the lower marital chances and the variation we found within the group of disabled people indicate the level of social exclusion they faced in society.

  14. Speleothem and biofilm formation in a granite/dolerite cave, Northern Sweden

    DEFF Research Database (Denmark)

    Sallstedt, T.; Ivarsson, M.; Lundberg, J.

    2014-01-01

    incorporated remains of microorganisms. Two types of microbial communities can be distinguished associated with the speleothems: an Actinobacteria-like biofilm and a fungal community. Actinobacteria seem to play an important role in the formation of speleothem while the fungal community acts as both...... a constructive and a destructive agent. A modern biofilm dominated by Actinobacteria is present in the speleothem-free parts of the dolerite and located in cave ceiling cracks. These biofilms may represent sites of early speleothem formation. Because of its unusual position in between two types of host rock...

  15. Inbreeding and fertility in Irish Wolfhounds in Sweden: 1976 to 2007

    Directory of Open Access Journals (Sweden)

    Urfer Silvan R

    2009-05-01

    Full Text Available Abstract Background Given that no influence of inbreeding on life expectancy could be demonstrated in Irish Wolfhounds in a previous study, it was decided to test the influence of inbreeding and other parameters on fertility in this breed. Methods The study was based on all Irish Wolfhound litters registered in Sweden between 1976 and 2007 (n = 822 litters as provided by the Swedish Kennel Club (SKK and combined with a pedigree database going back to 1862. Analyses were performed using linear regression in a Generalised Linear Model and other tests in the SAS system®. Results Mean number of pups per litter was 6.01 ± 2.65, with a maximum of 13. There were no significant differences in either the number of litters or the number of pups between years of birth. Males were used for breeding at a significantly earlier age than females. Mean number of litters per parent was 2.96 ± 3.14 for males and 1.59 ± 0.87 for females. No influence of Wright's inbreeding coefficients over 5, 10, 20 and 30 generations and/or Meuwissen's inbreeding coefficients on litter size was detected. In the Generalised Linear Model, highly significant, but weak (coefficient of determination (R2 = 0.0341 influences were found for maternal age at mating as well as maternal inbreeding measured by Wright's inbreeding coefficient over 30 generations and Meuwissen's inbreeding coefficient. Paternal inbreeding coefficients over 5, 10, 20 and 30 generations and calculated after Meuwissen, as well as maternal inbreeding coefficients over 5, 10 and 20 generations did not have significant effects on litter size. Conclusion The low coefficient of determination (R2 value of the Generalised Linear Model indicates that inbreeding does not have a strong influence on fertility in Irish Wolfhounds, which is consistent with earlier results and the breed's genetic history. These results likely reflect the aforementioned genetic history and should not be extrapolated to other breeds without

  16. Income distribution and mortality in Sweden

    Directory of Open Access Journals (Sweden)

    Christina Lindholm

    2008-12-01

    Full Text Available

    Background: The hypothesis that a high income inequality on a societal level is associated with poor health outcomes has been both rejected and accepted in empirical studies. Whether the influence of economic circumstances on health operates at the individual level or societal level has important implications on policy and intervention alternatives. The objective of this study was to analyse the relationship between income inequality and mortality in Swedish municipalities and if the relationship varies depending on the mean income or on the time-lag between income inequality and mortality.

    Methods: The study was based on register data on mean income and income inequality (Gini coefficients from Statistics Sweden 1982 and 1998, aggregated on the municipality level. Data on age-standardised death rates per 100,000 persons were obtained for 1983, 1988, 1993, 1998 and 2002. The analysis on 1998 was a test of the robustness of the results.

    Results: The relationship between high income inequality in 1982 and mortality in 1983 was negative with a similar relationship in 1998. Using latency periods, the results show a decreasing trend of mortality in relation to higher Gini coefficients. A positive relationship between Gini and mean income implies that municipalities with larger income distribution also had a higher mean income and vice versa.

    Conclusions: High income inequality does not have a negative effect on mortality in Swedish municipalities. The municipalities with high income inequality have also high mean income as opposed to many other countries. The income level seems to be more substantial for mortality than the income inequality.

  17. A review of the seismotectonics of Sweden

    International Nuclear Information System (INIS)

    Muir Wood, R.

    1993-04-01

    A study has been undertaken of data relating to the seismotectonic state of Sweden, both under current conditions and also through the glaciation/deglaciation cycle. The focus of the study has been to explore primary data on all the separate sources of information bearing on seismotectonics including: a. regional tectonics, b. neotectonic surface faulting, c. geodetic and tide-gauge observations of land-level changes, d. the horizontal strain field, e. Holocene land-level changes, f. historical and instrumental seismicity, g. palaeosesmicity, h. stress determinations, and i. geothermal observations. These data have then been combined into a regional seismotectonic model, relating the distribution, style and rates of seismicity to the seismogenic properties of the crust and the continuing crustal deformation. From the evidence of the modelled and observed horizontal strain field and the diversity of focal mechanisms, all the current seismicity of the region appear to be a response to postglacial rebound. Through and understanding of the interaction between the pre-existing tectonic strain field, and the strain field resulting from glacial loading and unloading it is possible to make testable predictions about the localisation of deformation and seismicity in Fennoscandia at different stages of the glacial cycle. Immediately following glacial unloading intense deformation was concentrated on the northwestern flank of the down warped crustal bowl. Currently low-level deformation and associated seismicity is most pronounced around the western margins of the dome of postglacial rebound. While the rebound dome is primarily extensional relieving the high levels of compression that accompanied crustal down warping, there are also areas of compression and extension associated with flexures in the rebound surface that appear to affect the distribution and style of seismicity. The study shows how the significance and localisation of deformation and seismicity may be predicted

  18. Thermomechanical studies in granite at Stripa, Sweden

    International Nuclear Information System (INIS)

    Cook, N.G.W.; Myer, L.R.

    1981-01-01

    Media other than rock salt are being considered for the deep, geologic disposal of nuclear wastes. The disposal of high-level nuclear waste in a deep, underground repository will subject the rock to a thermal pulse that will induce displacements, strains, and stresses in the rock. Thermomechanical experiments, with electrical heaters simulating the thermal output of waste canisters, were carried out in granite at a depth of 340 m below surface adjacent to a defunct iron ore mine at Stripa, Sweden. Changes in temperature, displacement, and stress in the rock around these heaters were measured, and the measurements were compared with predictions calculated from the theory of linear thermoelasticity. Measured temperature changes agreed well with predictions, but measured displacements and stresses were consistently less than those predicted with constant values for the coefficient of thermal expansion and elastic properties of the rock. A laboratory test program to measure these coefficients over ranges of stress and temperature representing those in the field experiment has been initiated. Test specimens were taken from cores recovered from the instrumentation holes in the Stripa experiments. Preliminary results from laboratory tests on specimens free of joints indicate that the values of Young's modulus and Poisson's ratio increase from about 60 to 80 MPa and from 0.15 to 0.22, respectively, as the confining stress is increased from 2 to 55 MPa; these values decrease with increasing temperature, more so at 2 MPa than at 55 MPa. The linear coefficient of thermal expansion at a confining stress of 30 MPa increases from about 10 x 10 - 6 / 0 C at 40 0 C to about 14 x 10 - 6 / 0 C. The magnitudes of these changes are not sufficient to resolve the disparity between measured and predicted results. Perhaps the properties of test specimens containing joints will show greater variations in the values of the thermomechanical coefficients with temperature and pressure

  19. Impact of climate change, seedling type and provenance on the risk of damage to Norway spruce (Picea abies (L.) Karst.) seedlings in Sweden due to early summer frosts

    Energy Technology Data Exchange (ETDEWEB)

    Langvall, Ola (Swedish Univ. of Agricultural Sciences, Unit for Field-based Forest Research, Asa Forest Research Station, Lammhult (Sweden))

    2011-04-15

    A model including site-specific microclimate-affecting properties of a forest regeneration area together with seedling characteristics was used to evaluate the accumulated risk of frost damage to Norway spruce (Picea abies (L.) Karst.) seedlings. Climate change in Sweden was simulated on the basis of the regional climate model RCA3. The daily average temperature, the driving factor for bud burst in the model, was adjusted using the difference between the mean of the climate model data for the years 1961-1990 and 2036-2065. The model was run for a highly frost prone, clear-cut site in which bare-rooted Norway spruce seedlings of mid-Swedish provenance were planted. Alternate runs were conducted with data for containerized seedlings and seedlings of Belarusian origin. The study showed that bud burst will occur at earlier dates throughout Sweden in the period 2036-2065 if the climate changes according to either of the climate scenarios examined, compared to the reference period 1961-1990. Furthermore, the risk of damage to Norway spruce seedlings as a result of frost events during summer will increase in southern Sweden and be unaffected or decrease in northern Sweden. The risk of frost damage was exacerbated in containerized seedlings, while the risk was lower for the seedlings of Belarusian provenance when compared with bare-rooted seedlings or seedlings of mid-Swedish origin

  20. Sex-specific heritability of spontaneous lipid levels in an extended pedigree of Indian-origin rhesus macaques (Macaca mulatta.

    Directory of Open Access Journals (Sweden)

    Amanda Vinson

    Full Text Available The rhesus macaque is an important model for human atherosclerosis but genetic determinants of relevant phenotypes have not yet been investigated in this species. Because lipid levels are well-established and heritable risk factors for human atherosclerosis, our goal was to assess the heritability of lipoprotein cholesterol and triglyceride levels in a single, extended pedigree of 1,289 Indian-origin rhesus macaques. Additionally, because increasing evidence supports sex differences in the genetic architecture of lipid levels and lipid metabolism in humans and macaques, we also explored sex-specific heritability for all lipid measures investigated in this study. Using standard methods, we measured lipoprotein cholesterol and triglyceride levels from fasted plasma in a sample of 193 pedigreed rhesus macaques selected for membership in large, paternal half-sib cohorts, and maintained on a low-fat, low cholesterol chow diet. Employing a variance components approach, we found moderate heritability for total cholesterol (h²=0.257, P=0.032, LDL cholesterol (h²=0.252, P=0.030, and triglyceride levels (h²=0.197, P=0.034 in the full sample. However, stratification by sex (N=68 males, N=125 females revealed substantial sex-specific heritability for total cholesterol (0.644, P=0.004, females only, HDL cholesterol (0.843, P=0.0008, females only, VLDL cholesterol (0.482, P=0.018, males only, and triglyceride levels (0.705, P=0.001, males only that was obscured or absent when sexes were combined in the full sample. We conclude that genes contribute to spontaneous variation in circulating lipid levels in the Indian-origin rhesus macaque in a sex-specific manner, and that the rhesus macaque is likely to be a valuable model for sex-specific genetic effects on lipid risk factors for human atherosclerosis. These findings are a first-ever report of heritability for cholesterol levels in this species, and support the need for expanded analysis of these traits in

  1. A procedure for the detection of linkage with high density SNP arrays in a large pedigree with colorectal cancer

    International Nuclear Information System (INIS)

    Middeldorp, Anneke; Wijnen, Juul T; Wezel, Tom van; Jagmohan-Changur, Shantie; Helmer, Quinta; Klift, Heleen M van der; Tops, Carli MJ; Vasen, Hans FA; Devilee, Peter; Morreau, Hans; Houwing-Duistermaat, Jeanine J

    2007-01-01

    The apparent dominant model of colorectal cancer (CRC) inheritance in several large families, without mutations in known CRC susceptibility genes, suggests the presence of so far unidentified genes with strong or moderate effect on the development of CRC. Linkage analysis could lead to identification of susceptibility genes in such families. In comparison to classical linkage analysis with multi-allelic markers, single nucleotide polymorphism (SNP) arrays have increased information content and can be processed with higher throughput. Therefore, SNP arrays can be excellent tools for linkage analysis. However, the vast number of SNPs on the SNP arrays, combined with large informative pedigrees (e.g. >35–40 bits), presents us with a computational complexity that is challenging for existing statistical packages or even exceeds their capacity. We therefore setup a procedure for linkage analysis in large pedigrees and validated the method by genotyping using SNP arrays of a colorectal cancer family with a known MLH1 germ line mutation. Quality control of the genotype data was performed in Alohomora, Mega2 and SimWalk2, with removal of uninformative SNPs, Mendelian inconsistencies and Mendelian consistent errors, respectively. Linkage disequilibrium was measured by SNPLINK and Merlin. Parametric linkage analysis using two flanking markers was performed using MENDEL. For multipoint parametric linkage analysis and haplotype analysis, SimWalk2 was used. On chromosome 3, in the MLH1-region, a LOD score of 1.9 was found by parametric linkage analysis using two flanking markers. On chromosome 11 a small region with LOD 1.1 was also detected. Upon linkage disequilibrium removal, multipoint linkage analysis yielded a LOD score of 2.1 in the MLH1 region, whereas the LOD score dropped to negative values in the region on chromosome 11. Subsequent haplotype analysis in the MLH1 region perfectly matched the mutation status of the family members. We developed a workflow for linkage

  2. Gambling in Sweden: the cultural and socio-political context.

    Science.gov (United States)

    Binde, Per

    2014-02-01

    To provide an overview, with respect to Sweden, of the cultural history of gambling, the commercialization of gambling, problem gambling research, the prevalence of problem gambling and its prevention and treatment. A review of the literature and official documents relating to gambling in Sweden; involvement in gambling research and regulation. Gambling has long been part of Swedish culture. Since about 1980 the gambling market, although still largely monopolistic, has been commercialized. At the same time, problem gambling has emerged as a concept in the public health paradigm. Debate regarding whether or not Sweden's national restrictions on the gambling market are compliant with European Community legislation has helped to put problem gambling on the political agenda. Despite expanded gambling services, the extent of problem gambling on the population level has not changed significantly over the past decade. The stability of problem gambling in Sweden at the population level suggests a homeostatic system involving the gambling market, regulation, prevention and treatment and adaption to risk and harm by gamblers. We have relatively good knowledge of the extent and characteristics of problem gambling in Sweden and of how to treat it, but little is known of how to prevent it effectively. Knowledge is needed of the effectiveness of regulatory actions and approaches, and of responsible gambling measures implemented by gambling companies. © 2013 The Author, Addiction © 2013 Society for the Study of Addiction.

  3. Genetic heterogeneity in familial exudative vitreoretinopathy; exclusion of the EVR1 locus on chromosome 11q in a large autosomal dominant pedigree.

    Science.gov (United States)

    Bamashmus, M A; Downey, L M; Inglehearn, C F; Gupta, S R; Mansfield, D C

    2000-04-01

    Familial exudative vitreoretinopathy (FEVR) is associated with mutations in the Norrie disease gene in X linked pedigrees and with linkage to the EVR1 locus at 11q13 in autosomal dominant cases. A large autosomal dominant FEVR family was studied, both clinically and by linkage analysis, to determine whether it differed from the known forms of FEVR. Affected members and obligate gene carriers from this family were examined by slit lamp biomicroscopy, indirect ophthalmoscopy, and in some cases fluorescein angiography. Patient DNAs were genotyped for markers at the EVR1 locus on chromosome 11q13. The clinical evaluation in this family is consistent with previous descriptions of FEVR pedigrees, but linkage analysis proves that it has a form of FEVR genetically distinct from the EVR1 locus on 11q. This proves that there are at least three different loci associated with comparable FEVR phenotypes, a situation similar to that existing for many forms of retinal degeneration.

  4. Genetic heterogeneity in familial exudative vitreoretinopathy; exclusion of the EVR1 locus on chromosome 11q in a large autosomal dominant pedigree

    OpenAIRE

    Bamashmus, M; Downey, L; Inglehearn, C; Gupta, S; Mansfield, D

    2000-01-01

    BACKGROUND/AIMS—Familial exudative vitreoretinopathy (FEVR) is associated with mutations in the Norrie disease gene in X linked pedigrees and with linkage to the EVR1 locus at 11q13 in autosomal dominant cases. A large autosomal dominant FEVR family was studied, both clinically and by linkage analysis, to determine whether it differed from the known forms of FEVR.
METHODS—Affected members and obligate gene carriers from this family were examined by slit lamp biomicroscopy, indirect ophthalmos...

  5. Pedigree with frontotemporal lobar degeneration – motor neuron disease and Tar DNA binding protein-43 positive neuropathology: genetic linkage to chromosome 9

    Directory of Open Access Journals (Sweden)

    Loy Clement T

    2008-08-01

    Full Text Available Abstract Background Frontotemporal lobar degeneration (FTLD represents a clinically, pathologically and genetically heterogenous neurodegenerative disorder, often complicated by neurological signs such as motor neuron-related limb weakness, spasticity and paralysis, parkinsonism and gait disturbances. Linkage to chromosome 9p had been reported for pedigrees with the neurodegenerative disorder, frontotemporal lobar degeneration (FTLD and motor neuron disease (MND. The objective in this study is to identify the genetic locus in a multi-generational Australian family with FTLD-MND. Methods Clinical review and standard neuropathological analysis of brain sections from affected pedigree members. Genome-wide scan using microsatellite markers and single nucleotide polymorphism fine mapping. Examination of candidate genes by direct DNA sequencing. Results Neuropathological examination revealed cytoplasmic deposition of the TDP-43 protein in three affected individuals. Moreover, we identify a family member with clinical Alzheimer's disease, and FTLD-Ubiquitin neuropathology. Genetic linkage and haplotype analyses, defined a critical region between markers D9S169 and D9S1845 on chromosome 9p21. Screening of all candidate genes within this region did not reveal any novel genetic alterations that co-segregate with disease haplotype, suggesting that one individual carrying a meiotic recombination may represent a phenocopy. Re-analysis of linkage data using the new affection status revealed a maximal two-point LOD score of 3.24 and a multipoint LOD score of 3.41 at marker D9S1817. This provides the highest reported LOD scores from a single FTLD-MND pedigree. Conclusion Our reported increase in the minimal disease region should inform other researchers that the chromosome 9 locus may be more telomeric than predicted by published recombination boundaries. Moreover, the existence of a family member with clinical Alzheimer's disease, and who shares the disease

  6. Development of genomic microsatellite multiplex PCR using dye-labeled universal primer and its validation in pedigree analysis of Pacific oyster ( Crassostrea gigas)

    Science.gov (United States)

    Liu, Ting; Li, Qi; Song, Junlin; Yu, Hong

    2017-02-01

    There is an increasing requirement for traceability of aquaculture products, both for consumer protection and for food safety. There are high error rates in the conventional traceability systems depending on physical labels. Genetic traceability technique depending on DNA-based tracking system can overcome this problem. Genealogy information is essential for genetic traceability, and microsatellite DNA marker is a good choice for pedigree analysis. As increasing genotyping throughput of microsatellites, microsatellite multiplex PCR has become a fast and cost-effective technique. As a commercially important cultured aquatic species, Pacific oyster Crassostrea gigas has the highest global production. The objective of this study was to develop microsatellite multiplex PCR panels with dye-labeled universal primer for pedigree analysis in C. gigas, and these multiplex PCRs were validated using 12 full-sib families with known pedigrees. Here we developed six informative multiplex PCRs using 18 genomic microsatellites in C. gigas. Each multiplex panel contained a single universal primer M13(-21) used as a tail on each locus-specific forward primer and a single universal primer M13(-21) labeled with fluorophores. The polymorphisms of the markers were moderate, with an average of 10.3 alleles per locus and average polymorphic information content of 0.740. The observed heterozygosity per locus ranged from 0.492 to 0.822. Cervus simulations revealed that the six panels would still be of great value when massive families were analysed. Pedigree analysis of real offspring demonstrated that 100% of the offspring were unambiguously allocated to their parents when two multiplex PCRs were used. The six sets of multiplex PCRs can be an important tool for tracing cultured individuals, population genetic analysis, and selective breeding program in C. gigas.

  7. Genetic genealogy comes of age: perspectives on the use of deep-rooted pedigrees in human population genetics.

    Science.gov (United States)

    Larmuseau, M H D; Van Geystelen, A; van Oven, M; Decorte, R

    2013-04-01

    In this article, we promote the implementation of extensive genealogical data in population genetic studies. Genealogical records can provide valuable information on the origin of DNA donors in a population genetic study, going beyond the commonly collected data such as residence, birthplace, language, and self-reported ethnicity. Recent studies demonstrated that extended genealogical data added to surname analysis can be crucial to detect signals of (past) population stratification and to interpret the population structure in a more objective manner. Moreover, when in-depth pedigree data are combined with haploid markers, it is even possible to disentangle signals of temporal differentiation within a population genetic structure during the last centuries. Obtaining genealogical data for all DNA donors in a population genetic study is a labor-intensive task but the vastly growing (genetic) genealogical databases, due to the broad interest of the public, are making this job more time-efficient if there is a guarantee for sufficient data quality. At the end, we discuss the advantages and pitfalls of using genealogy within sampling campaigns and we provide guidelines for future population genetic studies. Copyright © 2013 Wiley Periodicals, Inc.

  8. A novel nonsense mutation of the GPR143 gene identified in a Chinese pedigree with ocular albinism.

    Directory of Open Access Journals (Sweden)

    Naihong Yan

    Full Text Available BACKGROUND: The purpose of this study was to elucidate the molecular basis of ocular albinism type I in a Chinese pedigree. METHODOLOGY/PRINCIPAL FINDINGS: Complete ophthalmologic examinations were performed on 4 patients, 7 carriers and 17 unaffected individuals in this five-generation family. All coding exons of four-point-one (4.1, ezrin, radixin, moesin (FERM domain-containing 7 (FRMD7 and G protein-coupled receptor 143 (GPR143 genes were amplified by polymerase chain reaction (PCR, sequenced and compared with a reference database. Ocular albinism and nystagmus were found in all patients of this family. Macular hypoplasia was present in the patients including the proband. A novel nonsense hemizygous mutation c.807T>A in the GPR143 gene was identified in four patients and the heterozygous mutation was found in seven asymptomatic individuals. This mutation is a substitution of tyrosine for adenine which leads to a premature stop codon at position 269 (p.Y269X of GPR143. CONCLUSIONS/SIGNIFICANCE: This is the first report that p.Y269X mutation of GPR143 gene is responsible for the pathogenesis of familial ocular albinism. These results expand the mutation spectrum of GPR143, and demonstrate the clinical characteristics of ocular albinism type I in Chinese population.

  9. Relationships among quantitative traits in F3, F4 and F5 wheat hybrids obtained by pedigree and bulk selection

    Directory of Open Access Journals (Sweden)

    Janković Snežana

    2010-01-01

    Full Text Available Relationships among quantitative traits of wheat were analyzed in parents and their F3, F4 and F5 hybrids. Three female parents (Briscard, Carifen 12 and Rescler were crossed with two male parents (Francuska and PKB-Prelivka. Same crosses were repeated 4 years, from 1996 to 1999. Hybrids were obtained via pedigree and bulk selection. In year 2000 the field experiments were set up with all parental and hybrid material, at the Institute 'PKB INI Agroekonomik', in Padinska Skela, near Belgrade. Six traits were measured: plant height, spike length, number of spikelets per spike, number of grains per spike, 1000 grain weight and grain weight per spike. In parental genotypes, it was found grain mass per spike was in significant and positive correlation with 1000 grain mass and number of grains per spike. As in parents, correlation between grain mass per spike and 1000 grain weight was almost functional in F3, F4 and F5 hybrids. However, correlation between grain mass per spike and number of grains per spike was negative or slight positive in hybrid descendents, what is surprising because it is oppositely to the parents. Similar values of correlation coefficients were found in both applied methods of selection. This fact shows correlations change between generations. Grain mass per spike depends on a 1000 grain mass in both, parental and hybrid generations. Stable relationship between traits could be use for selection of high yielding genotypes.

  10. Transcriptomic Analysis of Induced Pluripotent Stem Cells Derived from Patients with Bipolar Disorder from an Old Order Amish Pedigree.

    Directory of Open Access Journals (Sweden)

    Kwi Hye Kim

    Full Text Available Fibroblasts from patients with Type I bipolar disorder (BPD and their unaffected siblings were obtained from an Old Order Amish pedigree with a high incidence of BPD and reprogrammed to induced pluripotent stem cells (iPSCs. Established iPSCs were subsequently differentiated into neuroprogenitors (NPs and then to neurons. Transcriptomic microarray analysis was conducted on RNA samples from iPSCs, NPs and neurons matured in culture for either 2 weeks (termed early neurons, E or 4 weeks (termed late neurons, L. Global RNA profiling indicated that BPD and control iPSCs differentiated into NPs and neurons at a similar rate, enabling studies of differentially expressed genes in neurons from controls and BPD cases. Significant disease-associated differences in gene expression were observed only in L neurons. Specifically, 328 genes were differentially expressed between BPD and control L neurons including GAD1, glutamate decarboxylase 1 (2.5 fold and SCN4B, the voltage gated type IV sodium channel beta subunit (-14.6 fold. Quantitative RT-PCR confirmed the up-regulation of GAD1 in BPD compared to control L neurons. Gene Ontology, GeneGo and Ingenuity Pathway Analysis of differentially regulated genes in L neurons suggest that alterations in RNA biosynthesis and metabolism, protein trafficking as well as receptor signaling pathways may play an important role in the pathophysiology of BPD.

  11. Development of Pedigree Classification Using Microsatellite and Mitochondrial Markers for Giant Grouper Broodstock (Epinephelus lanceolatus Management in Taiwan

    Directory of Open Access Journals (Sweden)

    Hsiao-Che Kuo

    2014-04-01

    Full Text Available Most giant groupers in the market are derived from inbred stock. Inbreeding can cause trait depression, compromising the animals’ fitness and disease resistance, obligating farmers to apply increased amounts of drugs. In order to solve this problem, a pedigree classification method is needed. Here, microsatellite and mitochondrial DNA were used as genetic markers to analyze the genetic relationships among giant grouper broodstocks. The 776-bp fragment of high polymorphic mitochondrial D-loop sequence was selected for measuring sibling relatedness. In a sample of 118 giant groupers, 42 haplotypes were categorized, with nucleotide diversity (π of 0.00773 and haplotype diversity (HD of 0.983. Furthermore, microsatellites were used for investigation of parentage. Six out of 33 microsatellite loci were selected as markers based on having a high number of alleles and compliance with Hardy-Weinberg equilibrium. Microsatellite profiles based on these loci provide high variability with low combined non-exclusion probability, permitting practical use in aquaculture. The method described here could be used to improve grouper broodstock management and lower the chances of inbreeding. This approach is expected to lead to production of higher quality groupers with higher disease resistance, thereby reducing the need for drug application.

  12. A novel AVPR2 gene mutation of X-linked congenital nephrogenic diabetes insipidus in an Asian pedigree.

    Science.gov (United States)

    Guo, Wei-Hong; Li, Qiang; Wei, Hong-Yan; Lu, Hong-Yan; Qu, Hui-Qi; Zhu, Mei

    2016-10-01

    Polyuria and polydipsia are the characteristics of congenital nephrogenic diabetes insipidus (CNDI). Approximately 90% of all patients with CNDI have X-linked hereditary disease, which is due to a mutation of the arginine vasopressin receptor 2 ( AVPR2) gene. This case report describes a 54-year-old male with polyuria and polydipsia and several male members of his pedigree who had the same symptoms. The proband was diagnosed with diabetes insipidus using a water-deprivation and arginine vasopressin stimulation test. Genomic DNA from the patient and his family members was extracted and the AVPR2 gene was sequenced. A novel missense mutation of a cytosine to guanine transition at position 972 (c.972C > G) was found, which resulted in the substitution of isoleucine for methionine at amino acid position 324 (p.I324M) in the seventh transmembrane domain of the protein. The proband's mother and daughter were heterozygous for this mutation. The novel mutation of the AVPR2 gene further broadens the phenotypic spectrum of the AVPR2 gene.

  13. Identification and Genetic Analysis of a Factor IX Gene Intron 3 Mutation in a Hemophilia B Pedigree in China

    Directory of Open Access Journals (Sweden)

    Dong Hua Cao

    2014-09-01

    Full Text Available OBJECTIVE: Hemophilia B is caused by coagulation defects in the factor IX gene located in Xq27.1 on the X chromosome. A wide range of mutations, showing extensive molecular heterogeneity, have been described in hemophilia B patients. Our study was aimed at genetic analysis and prenatal diagnosis of hemophilia B in order to further elucidate the pathogenesis of the hemophilia B pedigree in China. METHODS: Polymerase chain reaction amplification and direct sequencing of all the coding regions was conducted in hemophilia B patients and carriers. Prenatal diagnosis of the proband was conducted at 20 weeks. RESULTS: We identified the novel point mutation 10.389 A>G, located upstream of the intron 3 acceptor site in hemophilia B patients. The fetus of the proband’s cousin was identified as a carrier. CONCLUSION: Our identification of a novel mutation in the F9 gene associated with hemophilia B provides novel insight into the pathogenesis of this genetically inherited disorder and also represents the basis of prenatal diagnosis.

  14. Development of Pedigree Classification Using Microsatellite and Mitochondrial Markers for Giant Grouper Broodstock (Epinephelus lanceolatus) Management in Taiwan

    Science.gov (United States)

    Kuo, Hsiao-Che; Hsu, Hao-Hsuan; Chua, Chee Shin; Wang, Ting-Yu; Chen, Young-Mao; Chen, Tzong-Yueh

    2014-01-01

    Most giant groupers in the market are derived from inbred stock. Inbreeding can cause trait depression, compromising the animals’ fitness and disease resistance, obligating farmers to apply increased amounts of drugs. In order to solve this problem, a pedigree classification method is needed. Here, microsatellite and mitochondrial DNA were used as genetic markers to analyze the genetic relationships among giant grouper broodstocks. The 776-bp fragment of high polymorphic mitochondrial D-loop sequence was selected for measuring sibling relatedness. In a sample of 118 giant groupers, 42 haplotypes were categorized, with nucleotide diversity (π) of 0.00773 and haplotype diversity (HD) of 0.983. Furthermore, microsatellites were used for investigation of parentage. Six out of 33 microsatellite loci were selected as markers based on having a high number of alleles and compliance with Hardy-Weinberg equilibrium. Microsatellite profiles based on these loci provide high variability with low combined non-exclusion probability, permitting practical use in aquaculture. The method described here could be used to improve grouper broodstock management and lower the chances of inbreeding. This approach is expected to lead to production of higher quality groupers with higher disease resistance, thereby reducing the need for drug application. PMID:24796300

  15. Population and pedigree studies reveal a lack of association between the dopamine D sub 2 receptor gene and alcoholism

    Energy Technology Data Exchange (ETDEWEB)

    Bolos, A.M.; Goldman, D.; Brown, G.L. (National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD (USA)); Lucas-Derse, S.; Ramsburg, M. (Program Resources Inc., Frederick, MD (USA))

    1990-12-26

    Using the dopamine D{sub 2} receptor clone {lambda}hD2G1, Blum et al recently found that the D{sub 2}/Taq 1 allele (A1) was present in 69{percent} of 35 deceased alcoholics but in only 20{percent} of an equal number of controls. To assess this association further, the authors evaluated the D{sub 2}/Taq 1 polymorphism and a single-strand conformation polymorphism detected by polymerase chain reaction and nondenaturing gel electrophoresis (PCR-SSCP) of the 3{prime} noncoding region of the D{sub 2} receptor gene. They studied 40 unrelated white alcoholics, 127 racially matched controls, and two white pedigrees. The Schedule for Affective Disorders and Schizophrenia-Lifetime Version (SADS-L) clinical diagnostic interviews were rated blindly by two clinicians. Alcoholics were subtyped according to age of onset, severity, presence of antisocial personality, and family history. No significant differences in either D{sub 2}/Taq 1 or PCR-SSCP allele frequencies were observed between alcoholics, subpopulations of alcoholics, or controls. The PCR-SSCP polymorphism provided independent information against linkage at the D{sub 2} receptor locus. This study does not support a widespread or consistent association between the D{sub 2} receptor gene and alcoholism.

  16. Energy in Sweden. Facts and figures 2007; Energilaeget 2007

    Energy Technology Data Exchange (ETDEWEB)

    2007-12-15

    Energy in Sweden 2007: Facts and Figures contains the tabular for most of the diagrams in the main publication. These data consist primarily of the results of the Agency's processing of basic data from Statistics Sweden. 2001 statistics for the period 1983-1999 where revised compared to data for previous editions. With effect from the 2001 edition, statistics are of preliminary character for the two last published years (2005 and 2006). Breakdowns into certain types of fuels vary somewhat depending on whether preliminary or final data is used. Further information about the statistics can be found in Energy in Sweden, chapter 8 Energy Facts. Please note that the figures have been rounded up or down, therefore totals do not always comply with the sum of individual figures

  17. Vocational Education and Industrial Relations: Sweden 1910–1975

    Directory of Open Access Journals (Sweden)

    Tobias Karlsson

    2018-02-01

    Full Text Available In this article we discuss vocational education in Sweden against the backdrop of the changing nature of industrial relations in the period from ca 1910 to 1975. Drawing upon evidence from official inquiries and case studies of two industries (forest industry and shipbuilding, we show that Sweden in the 1940s and 1950s can be described as a collective skill formation system in the making, where firms, intermediary associations, and the state cooperated around vocational education and training. However, Sweden developed in a very different direction than similar countries. We argue that this remarkable change of trajectory cannot be understood without considering the simultaneous disintegration of the model of industrial relations, along with general changes in the system of education.

  18. Public and political attitudes to nuclear power in Sweden

    International Nuclear Information System (INIS)

    Wikdahl, C.-E.; Swedish Atomic Forum)

    1988-01-01

    The first important decisions about a large nuclear programme in Sweden were taken in the early 1960s without any political opposition at all. The first signs of an anti-nuclear movement were seen in 1972, and at the general election in 1976 nuclear power was for the first time the main political issue. It remained so until 1980, when Parliament, after a referendum, decided to phase out nuclear power not later than the year 2010. After that decision, political interest in nuclear power evaporated, but returned again after the Chernobyl accident in April 1986. Both the decision in Parliament in 1980 and the Government's bill of May 1987 put Sweden in an unique position. Public attitudes and the political situation in Sweden are examined. (author)

  19. Quality of renewable energy utilization in transport in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Lampinen, Ari

    2015-04-01

    Renewable energy utilization in transportation (RES-T) is a long way behind its utilization in power (RES-E) and heat (RES-H) sectors. International and national environmental policies have recently given a lot of emphasis on this problem. For that reason information is sought on how to implement solutions both politically and technologically. As Sweden is a global leader in this area, it can provide valuable examples. In 2012 Sweden became the first country to reach the binding requirement of the European Union for at least 10 % share for renewable energy in transport energy consumption. But qualitative development has been even stronger than quantitative. Among the success stories behind qualitative progress, most noteworthy are those created by innovative municipal policies. By 2030 Sweden aims to achieve fossil fuel independent road transport system and by 2050 completely carbon neutral transport system in all modes of transport.

  20. An electric-drive vehicle strategy for Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Sperling, D.; Lipman, T. [California Univ., Davis, CA (United States). Inst. of Transportation Studies; Lundberg, M. [Swedish Transport and Communications Research Board, Stockholm (Sweden)

    2000-07-01

    The strategy that Sweden has taken regarding the use of electric-powered vehicles (EVs) to mitigate the environmental impacts caused by the transportation sector was discussed. Sweden's unique attributes include inexpensive and clean electricity, a strong environmental ethic and a strong automotive sector. All versions of electric-drive technology are considered to be environmentally superior to internal combustion engine vehicles. While the cost of batteries is dropping, they will remain highly priced. However, manufacturers are making larger investments into hybrid EVs and fuel cell EVs. Electric drive buses are also gaining in popularity as a means by which to reduce exhaust gases in urban areas. Sweden's industrial policy is aimed at manufacturing electrically driven heavy duty vehicles such as buses and trucks. The environmental policy is aimed at deploying small EVs for on and off-road transportation use, as well as heavy duty EVs targeted by the industrial policy. refs.

  1. Air Pollution Mortality in Denmark, Finland, and Sweden

    Directory of Open Access Journals (Sweden)

    Ulla Lehmijoki

    2009-01-01

    Full Text Available The adverse health consequences of air pollution are of concern currently and there is a fear that these consequences escalate along with economic growth. The effect of economic growth on air pollution deaths is analyzed in Denmark, Finland, and Sweden by applying the Environmental Kuznets Curve approach, according to which economic growth has competing effects on air pollution and related deaths. On the one hand, emissions tend to increase as the scale of economic activity increases, but on the other hand, consumers and firms in richer countries use cleaner goods and adopt cleaner technologies. In Denmark and Finland, the latter effects are stronger, while in Sweden the opposite is true. Therefore, air pollution deaths will decrease in Denmark and Finland but increase in Sweden. Since country's own emissions do not determine air pollution completely, the paper briefly analyzes emissions from the Baltic countries and Russia.

  2. Monitoring of biting midges (Diptera: Ceratopogonidae: Culicoides Latreille) on farms in Sweden during the emergence of the 2008 epidemic of bluetongue

    DEFF Research Database (Denmark)

    Nielsen, Søren Achim; Nielsen, Boy Overgaard; Chirico, Jan

    2010-01-01

    In light of the emergence of bluetongue in northern Europe, populations of Culicoides species were monitored in 2007-2008 by means of Onderstepoort blacklight suction traps operating at livestock farms in Sweden. The location of the 22 sampling sites ranged from about latitude 55°N to about 68°N....... A total of 61,669 male and female Culicoides were captured, of which, 52,319 were trapped outside the farms and 9,350 in byres or livestock sheds. Thirty-three Culicoides species were recorded, of which, 30 were new to Sweden. The species and their relative abundance and spatial distribution on sites...... are presented. Two species incriminated as vectors of bluetongue virus, viz. Culicoides obsoletus (about 38%) and Culicoides scoticus (about 36%), were predominant and common in the environment of livestock farms practically all over the Swedish mainland, penetrating far north to at least 65°N. The two species...

  3. Sweden's Leadership in a Climate Constrained World. An analysis for Sweden of the Greenhouse Development Rights framework

    Energy Technology Data Exchange (ETDEWEB)

    Kartha, Sivan; Baer, Paul; Athanasiou, Tom; Kemp-Benedict, Eric

    2008-10-15

    This report presents an analysis of the Greenhouse Development Rights framework applied to the case of Sweden. Its objective is to provide useful quantitative guidance on Sweden's role as a leader in our climate constrained world. It presents guidance that is rigorous from the standpoint of climate science and framed in the context of a right to development for the world's poor. This analysis fully accounts for Sweden's true responsibility, by looking beyond territorial emissions alone, and reckoning emissions in terms of Sweden's net 'carbon footprint.' Accounting for carbon embedded in imports, exports and international transport reveals that Sweden's responsibility is 17% larger than would be inferred by considering Sweden's territorial emissions alone. Sweden will naturally have significant obligations under any burden-sharing regime that is based on capacity and responsibility, and only more so under a regime that honors a right to development. Under the GDR framework, our indicative quantification suggests that Sweden's share of responsibility and capacity, and hence its obligation under a politically viable climate regime, will be approximately 0.51% of the global total in 2010. This can be compared to the US's 33%, the EU's 26%, Japan's 7.8%, China's 5.5%, and India's 0.5%. Sweden's 0.51% share of the global total is thus not large in absolute terms, though it is rather large relative to Sweden's small size (0.14% of the global population). These national shares shift over time, as countries' relative proportion of income and emissions change. In light of the emergence of rapidly growing developing country economies, Sweden's share of the global total obligation is projected to decline to 0.43% by 2020, and to 0.35% by 2030. This quantification of Sweden's obligation is useful in two complementary ways. First, if the total global costs of an emergency climate

  4. Potentially avoidable perinatal deaths in Denmark and Sweden 1991

    DEFF Research Database (Denmark)

    Langhoff-Roos, J; Borch-Christensen, H; Larsen, S

    1996-01-01

    to some extent could reflect differences in the quality of care, indicated by the numbers of perinatal deaths in categories of potentially avoidable deaths. MATERIAL AND METHODS: Medical records of 97% of all perinatal deaths in 1991 in the two countries were analyzed. A new classification focusing......BACKGROUND: Since 1950 the perinatal mortality has been significantly higher in Denmark than in Sweden. In 1991 the rate in Denmark was 8.0/1000 deliveries compared to 6.5/1000 in Sweden. An international audit was designed to investigate whether the perinatal death rates in the two countries...

  5. Occurrence of the hermit beetle (Osmoderma eremita), in Sweden.

    OpenAIRE

    Antonsson, Kjell; Hedin, Jonas; Jansson, Niklas; Nilsson, Sven; Ranius, Thomas

    2003-01-01

    We have compiled data on the occurrence of a threatened beetle, Osmoderma eremita, in Sweden. The species inhabits tree hollows with wood mould. The data were compiled from field surveys conducted in 1993-2003, using pitfall traps at 401 localities and using wood mould sampling at 104 localities. We have also gone through published data and all larger Swedish museums and registered old records. O. eremita was recorded at about 30% of the field surveys. In Sweden, oak is by far the most import...

  6. Potentially avoidable perinatal deaths in Denmark and Sweden 1991

    DEFF Research Database (Denmark)

    Langhoff-Roos, J; Borch-Christensen, H; Larsen, S

    1996-01-01

    BACKGROUND: Since 1950 the perinatal mortality has been significantly higher in Denmark than in Sweden. In 1991 the rate in Denmark was 8.0/1000 deliveries compared to 6.5/1000 in Sweden. An international audit was designed to investigate whether the perinatal death rates in the two countries...... to some extent could reflect differences in the quality of care, indicated by the numbers of perinatal deaths in categories of potentially avoidable deaths. MATERIAL AND METHODS: Medical records of 97% of all perinatal deaths in 1991 in the two countries were analyzed. A new classification focusing...

  7. Sustainable Development in Sweden - a success story. Discourse analysis

    International Nuclear Information System (INIS)

    Ahlberg, Malin

    2009-01-01

    In Sweden the term 'Sustainable Development' is very well known and is often used as leitmotivs in many parts of the society. Since the UN Conference on Environment and Development took place in Rio de Janeiro 1992 SD has become more and more indispensable in political debates and it has even become a crucial argument in management decisions in the business sector. Due to the tradition of consensus policy and the strong involvement of different interest group in policy decision-making processes, the idea of SD as a holistic policy concept fell in Sweden on a fruitful ground

  8. Parental leave and the glass ceiling in Sweden

    OpenAIRE

    Albrecht, James; Skogman Thoursie, Peter; Vroman, Susan

    2015-01-01

    In this paper, we update and extend "Is There a Glass Ceiling in Sweden?" (Albrecht et al. 2003) by documenting the extent to which the gender log wage gap across the distribution in Sweden has changed over the period 1998-2008. We then examine the Swedish glass ceiling in 2008 in more detail by documenting how it differs for white-collar versus blue-collar workers and for private- versus public-sector workers. We also examine when in the life cycle the glass ceiling effect arises and how thi...

  9. Energy in Sweden: Facts and figures 2009; Energilaeget 2009

    Energy Technology Data Exchange (ETDEWEB)

    2009-12-15

    Energy in Sweden 2009: Facts and figures contains the tabular for most of the diagrams in the main publication (STEM-ET--2009-30). These data consist primarily of the results of the Agency's processing of basic data from Statistics Sweden. Statistics are of preliminary character for the two last published years (2007 and 2008). Breakdowns into certain types of fuels vary somewhat depending on whether preliminary or final data is used. Please note that the figures have been rounded up or down, therefore totals do not always comply with the sum of individual figures

  10. The geomorphic impact of glaciers as indicated by tors in North Sweden (Aurivaara, 68° N)

    Science.gov (United States)

    André, Marie-Françoise

    2004-02-01

    Geomorphological investigations carried out on 15 tor-like features located on the Aurivaara plateau (North Sweden, 68° N) provide new insights in the greatly debated age of these landforms. Erratics and till trapped deep in the tor joints support a pre-Weichselian age for tor formation. Moreover, the occurrence of various weathering stages in allochtonous material, the joint width up to 1.5 m (requiring long-term weathering), and the frequent association of tors with pediment-like forms, suggest pre-Quaternary tor formation. The juxtaposition of fresh erratics and in situ old weathering features (mushroom rocks, concentrically weathered well-rounded corestones, and grus) indicates a predominantly cold-based regime for the Scandinavian ice sheet, with erratics carried by the overlying moving ice being repeatedly deposited on tor summits during deglaciation phases. The relationships between tors and ice action indicated for the Aurivaara plateau result in the proposal of a morphodynamical succession of five tor subtypes ranging from the preservation of well-rounded corestones still embedded in grus (suggesting negligible glacial erosion) to the almost complete removal of tor features by ice scouring. A comparison with tors in similar geological and topographical contexts from the unglaciated Dartmoor area allows a tentative evaluation of an average overall glacial erosion of 0-10 m on the northern Sweden plateaus, in sharp contrast with the 190 m overdeepening of the nearby Torneträsk basin. Thus, this case study of Swedish tors provides additional support to the recent interpretations of relict landscapes in previously glaciated areas and is in accordance with the classical «model» of glacial selective erosion established in the Nordic and Arctic mountains.

  11. Modelling Regional Climate Change Effects On Potential Natural Ecosystems in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Koca, D.; Smith, B.; Sykes, M.T. [Centre for GeoBiosphere Science, Department of Physical Geography and Ecosystems Analysis, Lund University, Soelvegatan 12, S-223 62 Lund (Sweden)

    2006-10-15

    This study aims to demonstrate the potential of a process-based regional ecosystem model, LPJ-GUESS, driven by climate scenarios generated by a regional climate model system (RCM) to generate predictions useful for assessing effects of climatic and CO2 change on the key ecosystem services of carbon uptake and storage. Scenarios compatible with the A2 and B2 greenhouse gas emission scenarios of the Special Report on Emission Scenarios (SRES) and with boundary conditions from two general circulation models (GCMs) - HadAM3H and ECHAM4/OPYC3 - were used in simulations to explore changes in tree species distributions, vegetation structure, productivity and ecosystem carbon stocks for the late 21st Century, thus accommodating a proportion of the GCM-based and emissions-based uncertainty in future climate development. The simulations represented in this study were of the potential natural vegetation ignoring direct anthropogenic effects. Results suggest that shifts in climatic zones may lead to changes in species distribution and community composition among seven major tree species of natural Swedish forests. All four climate scenarios were associated with an extension of the boreal forest treeline with respect to altitude and latitude. In the boreal and boreo-nemoral zones, the dominance of Norway spruce and to a lesser extent Scots pine was reduced in favour of deciduous broadleaved tree species. The model also predicted substantial increases in vegetation net primary productivity (NPP), especially in central Sweden. Expansion of forest cover and increased local biomass enhanced the net carbon sink over central and northern Sweden, despite increased carbon release through decomposition processes in the soil. In southern Sweden, reduced growing season soil moisture levels counterbalanced the positive effects of a longer growing season and increased carbon supply on NPP, with the result that many areas were converted from a sink to a source of carbon by the late 21st

  12. Modelling Regional Climate Change Effects On Potential Natural Ecosystems in Sweden

    International Nuclear Information System (INIS)

    Koca, D.; Smith, B.; Sykes, M.T.

    2006-01-01

    This study aims to demonstrate the potential of a process-based regional ecosystem model, LPJ-GUESS, driven by climate scenarios generated by a regional climate model system (RCM) to generate predictions useful for assessing effects of climatic and CO2 change on the key ecosystem services of carbon uptake and storage. Scenarios compatible with the A2 and B2 greenhouse gas emission scenarios of the Special Report on Emission Scenarios (SRES) and with boundary conditions from two general circulation models (GCMs) - HadAM3H and ECHAM4/OPYC3 - were used in simulations to explore changes in tree species distributions, vegetation structure, productivity and ecosystem carbon stocks for the late 21st Century, thus accommodating a proportion of the GCM-based and emissions-based uncertainty in future climate development. The simulations represented in this study were of the potential natural vegetation ignoring direct anthropogenic effects. Results suggest that shifts in climatic zones may lead to changes in species distribution and community composition among seven major tree species of natural Swedish forests. All four climate scenarios were associated with an extension of the boreal forest treeline with respect to altitude and latitude. In the boreal and boreo-nemoral zones, the dominance of Norway spruce and to a lesser extent Scots pine was reduced in favour of deciduous broadleaved tree species. The model also predicted substantial increases in vegetation net primary productivity (NPP), especially in central Sweden. Expansion of forest cover and increased local biomass enhanced the net carbon sink over central and northern Sweden, despite increased carbon release through decomposition processes in the soil. In southern Sweden, reduced growing season soil moisture levels counterbalanced the positive effects of a longer growing season and increased carbon supply on NPP, with the result that many areas were converted from a sink to a source of carbon by the late 21st

  13. Sweden-Norway at the Berlin Conference 1884-85 : History, national identity-making and Sweden's relations with Africa

    OpenAIRE

    Nilsson, David

    2013-01-01

    The international image of Sweden is one of a small, democratic and peace-loving country without the moral burden of a colonial past. This image has been reproduced in Swedish government policy as well as in most historical accounts. However, in this Current African Issues publication, the notion that “Sweden lacks a colonial past in Africa” is brought into question. The Berlin Conference 1884-85 is perhaps the most infamous political event in the history of European domination of Africa. At ...

  14. Impact of DMI and SDHI fungicides on disease control and CYP51 mutations in populations of Zymoseptoria tritici from Northern Europe

    DEFF Research Database (Denmark)

    Wieczorek, Thies Marten; Berg, Gunilla; Semaskiene, Roma

    2015-01-01

    Zymoseptoria tritici is a dominant pathogen in wheat causing Septoria leaf blotch (SLB), and sterol 14α-demethylation inhibitors fungicides (DMI) are commonly used for control in Northern Europe. In 14 winter wheat trials carried out in Denmark, Lithuania, and Sweden in the years 2011 to 2013, fu...

  15. Forecast of icing events at a wind farm in Sweden

    DEFF Research Database (Denmark)

    Davis, Neil; Hahmann, Andrea N.; Clausen, Niels-Erik

    2014-01-01

    This paper introduces a method for identifying icing events using a physical icing model, driven by atmospheric data from the Weather Research and Forecasting (WRF) model, and applies it to a wind park in Sweden. Observed wind park icing events were identified by deviation from an idealized power...

  16. The management of intermediate level wastes in Sweden

    International Nuclear Information System (INIS)

    Hultgren, Aa.; Thegerstroem, C.

    1980-01-01

    A brief overview of current practices and research in Sweden on the management of intermediate level wastes is given. Intermediate level wastes include spent resins, filters and core components from the six power reactors in operation; radioactive wastes from nuclear fuel development at Studsvik and from non-nuclear applications are a minor contribution. (Auth.)

  17. Social Policy and Immigrant Joblessness in Britain, Germany and Sweden

    Science.gov (United States)

    Kesler, Christel

    2006-01-01

    I examine patterns of joblessness among immigrant men and women from 33 countries of origin now living in Britain, Germany and Sweden. Access to welfare, access to the labor market, job segregation and institutional support for women's employment define distinct policy configurations in these three destinations. Findings show that gaps in…

  18. At the Bridging Point: Tutoring Newly Arrived Students in Sweden

    Science.gov (United States)

    Avery, Helen

    2017-01-01

    In Sweden, tutoring in the mother tongue is a special support measure primarily intended for newly arrived students to facilitate their transition into the Swedish school system. Tutoring is premised on the collaboration between the class teacher, responsible for subject-related expertise, and the tutor, who contributes with knowledge of the…

  19. Students' Perspectives on Raising Achievement through Inclusion in Essunga, Sweden

    Science.gov (United States)

    Allan, Julie; Persson, Elisabeth

    2016-01-01

    A Swedish municipality that has transformed its position at the bottom of the national school league tables to top within three years--through inclusive education--has attracted much attention both in Sweden and internationally. This article offers the students' perspectives on the transformation and how they have experienced success. A social…

  20. Consequences of the Chernobyl accident for reindeer husbandry in Sweden

    International Nuclear Information System (INIS)

    Åhman, G.; Rydberg, A.; Åhman, B.

    1990-01-01

    Large parts of the reindeer hearding area in Sweden were contaminated with radioactive caesium from the Chernobyl fallout. During the first year after the accident no food with activity concentrations exceeding 300 Bq/kg was allowed to be sold in Sweden. This meant that about 75% of all reindeer meat produced in Sweden during the autumn and winter 1986/87 were rejected because of too high caesium activités. In May 1987 the maximum level for Cs-137 in reindeer, game and fresh-water fish was raised to 1500 Bq/kg. During the last two year, 1987/88 and 1988/89, about 25% of the slaughtered reindeer has had activities exceeding this limit. The effective long-time halflife or radiocaesium in reindeer after the nuclear weapon tests in the sixties was about 7 years. If this halflife is correct also for the Chernobyl fallout it will take about 35 years before most of the reinder in Sweden are below the current limit 1500 Bq/kg in the winter. However, by feeding the animals uncontaminated food for about two months, many reindeer can be saved for human consumption

  1. Coordination between primary and secondary healthcare in Denmark and Sweden

    Directory of Open Access Journals (Sweden)

    Sarah Wadmann

    2009-03-01

    Full Text Available Introduction: Insights into effective policy strategies for improved coordination of care is needed. In this study we describe and compare the policy strategies chosen in Denmark and Sweden, and discuss them in relation to interorganisational network theory. Policy practice: The policy initiatives to improve collaboration between primary and secondary healthcare in Denmark and Sweden include legislation and agreements aiming at clarifying areas of responsibility and defining requirements, creation of links across organisational boarders. In Denmark many initiatives have been centrally induced, while development of local solutions is more prominent in Sweden. Many Danish initiatives target the administrative level, while in Sweden initiatives are also directed at the operational level. In both countries economic incentives for collaboration are weak or lacking, and use of sanctions as a regulatory mean is limited. Discussion and conclusion: Despite a variety of policy initiatives, lacking or poorly developed structures to support implementation function as barriers for coordination. The two cases illustrate that even in two relatively coherent health systems, with regional management of both the hospital and general practice sector, there are issues to resolve in regard to administrative and operational coordination. The interorganisational network literature can provide useful tools and concepts for interpreting such issues.

  2. Consequences of the Chernobyl accident for reindeer husbandry in Sweden

    Directory of Open Access Journals (Sweden)

    Gustaf Åhman

    1990-09-01

    Full Text Available Large parts of the reindeer hearding area in Sweden were contaminated with radioactive caesium from the Chernobyl fallout. During the first year after the accident no food with activity concentrations exceeding 300 Bq/kg was allowed to be sold in Sweden. This meant that about 75% of all reindeer meat produced in Sweden during the autumn and winter 1986/87 were rejected because of too high caesium activités. In May 1987 the maximum level for Cs-137 in reindeer, game and fresh-water fish was raised to 1500 Bq/kg. During the last two year, 1987/88 and 1988/89, about 25% of the slaughtered reindeer has had activities exceeding this limit. The effective long-time halflife or radiocaesium in reindeer after the nuclear weapon tests in the sixties was about 7 years. If this halflife is correct also for the Chernobyl fallout it will take about 35 years before most of the reinder in Sweden are below the current limit 1500 Bq/kg in the winter. However, by feeding the animals uncontaminated food for about two months, many reindeer can be saved for human consumption.

  3. The Progressive Development of Environmental Education in Sweden and Denmark

    Science.gov (United States)

    Breiting, Soren; Wickenberg, Per

    2010-01-01

    Our paper traces the history and progressive development of environmental education and education for sustainable development (ESD) in Sweden and Denmark. Our main focus is on work in primary and lower secondary schools as part of a search for trends of international interest related to the conceptualisation and practice of environmental education…

  4. The Use of Personal Identity Numbers in Sweden and Denmark

    DEFF Research Database (Denmark)

    Hyltén-Cavallius, Katarina

    2015-01-01

    The paper of Katarina Hyltén-Cavallius focuses on personal identity numbers in Sweden and Denmark. This paper looks into formal and informal structures, which organise society in a host member state and which can make it difficult for a non-national Union citizen to, in practice, access public an...

  5. Is There Hidden Potential for Rural Population Growth in Sweden?

    Science.gov (United States)

    Niedomysl, Thomas; Amcoff, Jan

    2011-01-01

    Rural depopulation is a concern in many countries, and various policy initiatives have been taken to combat such trends. This article examines whether hidden potential for rural population growth can be found in Sweden. If such potential exists, it implies that the development prospects for many rural areas are not as unpromising as they may seem…

  6. Energy policies of IEA countries. Sweden 1996 review

    International Nuclear Information System (INIS)

    1996-01-01

    This IEA report provides a comprehensive, in-depth assessment of the energy policies of Sweden, including recommendations on future policy developments. Electricity is a focal point of Sweden's energy policy. After a shift in the energy mix to favour electricity in the early 1970's, nuclear and hydro power each make up about half of the electricity supply. Two key events have occurred since then: the 1980 referendum, which calls for the phase-out of all nuclear plants by 2010; the recent restructuring and liberalization of the electricity sector with the creation of a Nordic electricity market. In this context, the report argues the case for making a decision now on the nuclear issue to clarify Sweden's electricity future. Other key issues highlighted in the report include Sweden's use of economic policy instruments such as a carbon tax to achieve energy and environment goals, and the adequacy and effectiveness of government efforts to promote biofuels and energy efficiency. This report forms part of a series of periodic in-depth reviews conducted and discussed by the IEA Member countries on a four-year cycle. Short reviews of energy policy developments in all twenty-three Member countries are published annually in Energy Policies of IEA Countries. (author). 13 figs., 9 tabs., 4 appends

  7. The Role of the School Library: Reflections from Sweden

    Science.gov (United States)

    Avery, Helen

    2014-01-01

    Libraries are critical learning spaces and may play a significant role in intercultural education initiatives, particularly in Sweden where the national curriculum ascribes central functions to libraries for learning activities. Unfortunately, the ways in which teachers and librarians may collaborate to leverage mutual resources is not fully…

  8. M.S.Sigyn - Simbol of Sweden waste transport success

    International Nuclear Information System (INIS)

    Gustavson, B.; Dibek, P.

    1995-01-01

    The article is devoted to the presently existing system in Sweden of spent nuclear fuel and radioactive wastes maritime transportation from NPPs to places of permanent and intermediate storage. Transport casks and penals, their maintenance and control system are described. Explanatory work with public is partially also considered. 1 tab

  9. Comparison of the energy structures in Denmark, France and Sweden

    International Nuclear Information System (INIS)

    Nifenecker, H.

    2003-12-01

    Denmark is an example of country which involves massively in the renewable energies development and in the energy efficiency, since 1980. Facing this policy, France and Sweden produce their energy without fossil energies, mainly from nuclear and hydroelectric power. These countries energy policies, providing not much of carbon dioxide emission, are compared by the author. (A.L.B.)

  10. Parental Divorce and Union Disruption among Young Adults in Sweden

    Science.gov (United States)

    Gahler, Michael; Hong, Ying; Bernhardt, Eva

    2009-01-01

    This article analyzes the impact of parental divorce on the disruption of marital and nonmarital unions among young adults in Sweden, using longitudinal data from repeated mail questionnaire surveys (1999 and 2003) with 1,321 respondents (aged 26, 30, and 34 in 2003). The study takes into account several possible mechanisms governing the…

  11. Russia’s Security Relations with Finland, Norway, and Sweden

    Science.gov (United States)

    2017-09-01

    NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA THESIS Approved for public release. Distribution is unlimited. RUSSIA’S SECURITY... RELATIONS WITH FINLAND, NORWAY, AND SWEDEN by Rory J. Hayden September 2017 Thesis Advisor: Mikhail Tsypkin Co-Advisor: David S. Yost...THIS PAGE INTENTIONALLY LEFT BLANK i REPORT DOCUMENTATION PAGE Form Approved OMB No. 0704-0188 Public reporting burden for this collection of

  12. Privatizing Education: Free School Policy in Sweden and England

    Science.gov (United States)

    Wiborg, Susanne

    2015-01-01

    The aim of this article is to investigate why Sweden, the epitome of social democracy, has implemented education reforms leading to an extraordinary growth in Free Schools in contrast to liberal England, where Free School policy has been met with enormous resistance. Conventional wisdom would predict the contrary, but as a matter of fact Sweden…

  13. This is how we manage Sweden's radioactive waste. Activities 1995

    International Nuclear Information System (INIS)

    1996-01-01

    SKB operates systems and facilities for the management and final disposal of spent nuclear fuel and other radioactive waste in Sweden. SKB has conducted extensive R, D and D work with regard to constructing a spent fuel encapsulation plant and a deep repository in crystalline bedrock. This annual report treats all the different activities without going into technical details

  14. The Ultimate in Flexitime: From Sweden, by Way of Volvo.

    Science.gov (United States)

    Bernstein, Paul

    1988-01-01

    In the Volvo component plant on Koping, Sweden, an innovative system of multiple shifts and flexible working hours is offered to employees. The system meets the needs of those who are available for work at certain times and helps curtail turnover and absenteeism. (JOW)

  15. Energy in Sweden. Facts and figures 1999; Energilaeget i siffror

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-11-01

    This supplement contains the tabular data of most of the diagrams in the main publication (Energy in Sweden 1999, STEM-ET-82-1999). The figures are based on preliminary statistics, and there may be minor differences between similar data in different sections or tables etc. All table headings and notes are given in both Swedish and English.

  16. The Effect of Mixed-Age Classes in Sweden

    Science.gov (United States)

    Lindstrom, Elly-Ann; Lindahl, Erica

    2011-01-01

    Mixed-aged (MA) classes are a common phenomenon around the world. In Sweden, these types of classes increased rapidly during the 1980s and 1990s, despite the fact that existing empirical support for MA classes is weak. In this paper, the effect of attending an MA class during grades 4-6 on students' cognitive skills is estimated. Using a unique…

  17. Electric power supply in Sweden 1979/80

    International Nuclear Information System (INIS)

    1981-01-01

    Generation, transmission and consumption of electricity for the year 1979/80 in Sweden are review in this report. The net supply of electricity in TWh was 60.2 from hydro, 20.1 from nuclear, 12.1 from fossil thermal and 1.4 imported. Detailed statistics are given for both consumption and generation. (L.E.)

  18. Wood production potential in poplar plantations in Sweden

    International Nuclear Information System (INIS)

    Christersson, Lars

    2010-01-01

    Shortage of oil, large variations in exports from Russia of wood to Europe, plenty of abandoned agriculture land, new ideas about a more intensive silviculture; these circumstances are driving forces in Sweden for planting fast-growing poplar and hybrid aspen clones on suitable land. The advantage of such trees is that the wood can be used for both energy (heat, biofuels, electricity), paper and for construction. Poplar clones bred in the USA and Belgium, and older hybrid aspen clones from Sweden, together with new poplar clones collected and selected for Swedish conditions from British Columbia, Canada, were planted during the 1990s in south and central Sweden. The stem diameters and heights of the trees have been measured during the last 10 years and the woody biomass production above ground has been calculated. MAI for all the plantations is 10-31 m 3 or 3-10 ton DM per hectare with the highest annual woody production of 45 m 3 or 15 ton DM per hectare in some years in a very dense plantation in the most southern part of Sweden. All the plantations have been fenced for at least the first ten years. The damage has been caused by stem canker, insects, leaf rust and by moose after removal of the fences. The possibilities for the use of poplar plantations as energy forest and vegetation filters are discussed. (author)

  19. The mites associated with Ips typographus in Sweden

    Science.gov (United States)

    John C. Moser; Hubertus H. Eidmann; Jan R. Regnander

    1989-01-01

    Twenty-four species of mites were found associated with Ips typographus (Linnaeus) collected from pherommone traps in Sweden, bringing to 38 the total recorded for this scolytid. Because three of the species are parasites, it may be possible to use them in biological control of I. typographus. Couplets from an earlier key to these...

  20. Sweden's Engagement with the Democratic People's Republic of Korea

    DEFF Research Database (Denmark)

    Andersson, Magnus; Bae, Jinsun

    2015-01-01

    on semistructured interviews of individuals who have taken part in Swedish engagement programs. Findings: - Besides having its embassy in Pyongyang and serving as a protecting power for the U.S., Sweden has provided capacity building programs for North Korean government officials and scholars and has taken part...

  1. Wood production potential in poplar plantations in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Christersson, Lars [Section of Short Rotation Forestry, VPE, SLU, Uppsala (Sweden)

    2010-09-15

    Shortage of oil, large variations in exports from Russia of wood to Europe, plenty of abandoned agriculture land, new ideas about a more intensive silviculture; these circumstances are driving forces in Sweden for planting fast-growing poplar and hybrid aspen clones on suitable land. The advantage of such trees is that the wood can be used for both energy (heat, biofuels, electricity), paper and for construction. Poplar clones bred in the USA and Belgium, and older hybrid aspen clones from Sweden, together with new poplar clones collected and selected for Swedish conditions from British Columbia, Canada, were planted during the 1990s in south and central Sweden. The stem diameters and heights of the trees have been measured during the last 10 years and the woody biomass production above ground has been calculated. MAI for all the plantations is 10-31 m{sup 3} or 3-10 ton DM per hectare with the highest annual woody production of 45 m{sup 3} or 15 ton DM per hectare in some years in a very dense plantation in the most southern part of Sweden. All the plantations have been fenced for at least the first ten years. The damage has been caused by stem canker, insects, leaf rust and by moose after removal of the fences. The possibilities for the use of poplar plantations as energy forest and vegetation filters are discussed. (author)

  2. 75 FR 57815 - Purified Carboxymethylcellulose From Finland, Mexico, Netherlands, and Sweden

    Science.gov (United States)

    2010-09-22

    ... Carboxymethylcellulose From Finland, Mexico, Netherlands, and Sweden AGENCY: United States International Trade Commission... carboxymethylcellulose from Finland, Mexico, Netherlands, and Sweden. SUMMARY: The Commission hereby gives notice of the... carboxymethylcellulose from Finland, Mexico, Netherlands, and Sweden would be likely to lead to continuation or...

  3. dbVOR: a database system for importing pedigree, phenotype and genotype data and exporting selected subsets.

    Science.gov (United States)

    Baron, Robert V; Conley, Yvette P; Gorin, Michael B; Weeks, Daniel E

    2015-03-18

    When studying the genetics of a human trait, we typically have to manage both genome-wide and targeted genotype data. There can be overlap of both people and markers from different genotyping experiments; the overlap can introduce several kinds of problems. Most times the overlapping genotypes are the same, but sometimes they are different. Occasionally, the lab will return genotypes using a different allele labeling scheme (for example 1/2 vs A/C). Sometimes, the genotype for a person/marker index is unreliable or missing. Further, over time some markers are merged and bad samples are re-run under a different sample name. We need a consistent picture of the subset of data we have chosen to work with even though there might possibly be conflicting measurements from multiple data sources. We have developed the dbVOR database, which is designed to hold data efficiently for both genome-wide and targeted experiments. The data are indexed for fast retrieval by person and marker. In addition, we store pedigree and phenotype data for our subjects. The dbVOR database allows us to select subsets of the data by several different criteria and to merge their results into a coherent and consistent whole. Data may be filtered by: family, person, trait value, markers, chromosomes, and chromosome ranges. The results can be presented in columnar, Mega2, or PLINK format. dbVOR serves our needs well. It is freely available from https://watson.hgen.pitt.edu/register . Documentation for dbVOR can be found at https://watson.hgen.pitt.edu/register/docs/dbvor.html .

  4. Elevated risks for amyotrophic lateral sclerosis and blood disorders in Ashkenazi schizophrenic pedigrees suggest new candidate genes in schizophrenia

    Energy Technology Data Exchange (ETDEWEB)

    Goodman, A.B. [Columbia Univ. School of Public Health, New York, NY (United States)

    1994-09-15

    Among relatives of Ashkenazi schizophrenic probands the rate of amyotrophic lateral sclerosis was 3/1,000, compared to expected population rates of approximately 2/100,000. Relative risk of bleeding disorders, including hematologic cancers, was increased more than three-fold compared to controls. Co-occurrence of motor neuron disease and blood dyscrasias, accompanied by psychosis, has long been recognized. A virally-mediated autoimmune pathogenesis has been proposed. However, the familial co-occurrence of these three disease entities raises the possibility that the disease constellation be considered as a manifestation of a common underlying genetic defect. Such expansion of the spectrum of affectation might enhance the power of both candidate gene and linkage studies. Based on these findings, the loci suggested as candidate regions in schizophrenia include a potential hot spot on chromosome 21q21-q22, involving the superoxide dismutase and amyloid precursor protein genes. Alternatively, genes on other chromosomes involved in the expression, transcription, or regulation of these genes, or associated with the illnesses of high frequency in these pedigrees are suggested. Candidates include the choroid plexus transport protein, transthyretin at 18q11.2-q12.1; the t(14;18)(q22;21) characterizing B-cell lymphoma-2, the most common form of hematologic cancer; and the 14q24 locus of early onset Alzheimer`s disease, c-Fos, transforming growth factor beta 3, and heat shock protein A2. Expression of hematologic cancers and the suggested candidate genes are known to involve retinoid pathways, and retinoid disregulation has been proposed as a cause of schizophrenia. 67 refs., 2 figs., 1 tab.

  5. Licensing procedure for nuclear power in Sweden. An international look with lessons for Sweden

    International Nuclear Information System (INIS)

    Gaahlin, Emil; Nilsson, Isabelle; Pettersson, Maria; Soederholm, Patrik

    2011-02-01

    In this study we present an in-depth analysis of the existing licensing procedure for nuclear power in Sweden, and the related processes towards different public authorities. In order to put the existing legislation into context we also analyze the legal and political prerequisites for the establishment of nuclear reactors during the 1970s. The purpose of this report is thus to: (a) analyze the legal and political conditions under which the existing nuclear power plants in Sweden were built; and (b) review and analyze the existing licensing procedure for nuclear power in the country. Four main statutes (and several subordinated regulations) apply in connection with the establishment of a new nuclear plant in Sweden, including the adoption of physical plans, a principal governmental decision on the permissibility of the plant and at least five major licenses. Physical planning according to the Planning and Building Act is primarily a municipal responsibility. A plan has to meet certain environmental requirements; not least the 'provisions on efficient management of natural resources' in the Environmental Code, indicating how different kinds of land and water areas should be used and thereby direct the location of different installations. The Swedish rules are complex and vague in many respects, and may therefore imply major uncertainties for a prospective investor. The legal protection is less unclear if an area is of national interest for a specific purpose, such as nature conservation, where it normally would not be possible to locate, say, a nuclear power plant. An area may also be of national interest for nuclear plants, which of course significantly alters the preconditions in favour of the plant project. The physical planning procedure comprises an 'environmental consideration' of the plan, including an 'environmental impact assessment' (EIA), provided the plan is likely to have significant effects on the environment. This 'programmatic EIA' does however not

  6. Northern European long term climate archives

    Energy Technology Data Exchange (ETDEWEB)

    Hohl, Veronica [Stockholm Univ. (Sweden)

    2005-01-01

    The Swedish Nuclear Fuel and Waste Management Company is responsible for the management and disposal of Sweden's radioactive waste. It is intended to deposit the spent nuclear fuel in a deep geological repository. This repository shall keep the radiotoxic material separated from humans and the environment for extended periods, from decades to millennia and possibly to geological timescales. During this time perspective climate induced changes such as shore-level displacement and evolution of permafrost and ice sheets are expected to occur which may affect the repository. The possible occurrence, extent and duration of these long-term changes, are therefore of interest when considering the assessment of repository performance and safety. The main climate parameters determining both surface and subsurface conditions are temperature and precipitation. As a result of the last advance of the Weichselian ice sheet only few geological archives exist, which contain information on past climatic conditions in Sweden before c 16,000 years BP. The purpose of this literature review is to compile and evaluate available information from Scandinavian, Northern and Central European geological archives, which record climatic conditions during the Weichselian time period. The compilation provides paleotemperature data sets, which may be used to explore the possible evolution of periglacial permafrost in Sweden. This report is a synopsis of 22 publications detailing climatic and environmental changes during the Weichselian time period in Northwestern Europe based on quantified paleotemperature records. Some of the data is presented as temperature curves which were digitised specifically for this report. The time range covered by the different publications varies considerably. Only few authors dealt with the whole Weichselian period and the majority cover only a few thousand years. This however is not considered to influence the reliability of the archives. The reason for the

  7. Northern European long term climate archives

    International Nuclear Information System (INIS)

    Hohl, Veronica

    2005-01-01

    The Swedish Nuclear Fuel and Waste Management Company is responsible for the management and disposal of Sweden's radioactive waste. It is intended to deposit the spent nuclear fuel in a deep geological repository. This repository shall keep the radiotoxic material separated from humans and the environment for extended periods, from decades to millennia and possibly to geological timescales. During this time perspective climate induced changes such as shore-level displacement and evolution of permafrost and ice sheets are expected to occur which may affect the repository. The possible occurrence, extent and duration of these long-term changes, are therefore of interest when considering the assessment of repository performance and safety. The main climate parameters determining both surface and subsurface conditions are temperature and precipitation. As a result of the last advance of the Weichselian ice sheet only few geological archives exist, which contain information on past climatic conditions in Sweden before c 16,000 years BP. The purpose of this literature review is to compile and evaluate available information from Scandinavian, Northern and Central European geological archives, which record climatic conditions during the Weichselian time period. The compilation provides paleotemperature data sets, which may be used to explore the possible evolution of periglacial permafrost in Sweden. This report is a synopsis of 22 publications detailing climatic and environmental changes during the Weichselian time period in Northwestern Europe based on quantified paleotemperature records. Some of the data is presented as temperature curves which were digitised specifically for this report. The time range covered by the different publications varies considerably. Only few authors dealt with the whole Weichselian period and the majority cover only a few thousand years. This however is not considered to influence the reliability of the archives. The reason for the varying

  8. Northern Dimension: Participant Strategies

    Directory of Open Access Journals (Sweden)

    Busygina Irina

    2009-03-01

    Full Text Available This article is devoted to the “Northern Dimension” initiative of the EU which also includes North-West Russia, Norway and Iceland. It is noted that the “Northern Dimension” in the theoretical perspective can be considered as part of strategic multi-level interactions between member-states of the EU and Russia. On this basis, the authors analyze implications and effects of the strategic interdependence of all the EU-Russia relation levels.

  9. Northern Dimension: Participant Strategies

    Directory of Open Access Journals (Sweden)

    Busygina I.

    2009-01-01

    Full Text Available his article is devoted to the “Northern Dimension” initiative of the EU which also includes North-West Russia, Norway and Iceland. It is noted that the “Northern Dimension” in the theoretical perspective can be considered as part of strategic multi-level interactions between member-states of the EU and Russia. On this basis, the authors analyze implications and effects of the strategic interdependence of all the EU-Russia relation levels.

  10. Risk factors and potential preventive measures for nephropatia epidemica in Sweden 2011–2012: a case–control study

    Directory of Open Access Journals (Sweden)

    Alin Gherasim

    2015-06-01

    Full Text Available Introduction: Nephropatia epidemica (NE, a relatively mild form of hemorrhagic fever with renal syndrome caused by the Puumala virus (PUUV, is endemic in northern Sweden. We aim to study the risk factors associated with NE in this region. Methods: We conducted a matched case–control study between June 2011 and July 2012. We compared confirmed NE cases with randomly selected controls, matched by age, sex, and place of infection or residence. We analyzed the association between NE and several occupational, environmental, and behavioral exposures using conditional logistic regression. Results: We included in the final analysis 114 cases and 300 controls, forming 246 case–control pairs. Living in a house with an open space beneath, making house repairs, living less than 50 m from the forest, seeing rodents, and smoking were significantly associated with NE. Conclusion: Our results could orient public health policies targeting these risk factors and subsequently reduce the NE burden in the region.

  11. Social Pedagogy in Finland and Sweden: a comparative analysis

    Directory of Open Access Journals (Sweden)

    Juha Hämäläinen

    2015-12-01

    Full Text Available Discussing how the concept of social pedagogy has been used in Finland and Sweden, this paper provides a historical and systemic comparison of policies and practices of social pedagogy in these two countries. The main aim is to identify and explain the main similarities and differences between the Finnish and Swedish national trajectories of social pedagogical thinking and action. In the first phase of the analysis, country-specific features of social pedagogy were described paying attention to historical and structural aspects. In the second phase, these descriptions were compared in a dialogue between the au- thors, one from Finland and the other from Sweden. The dialogue-based comparison was targeted to ex- plain the identified similar and different features of social pedagogical policies and practices. The explanation was based on historical and systemic considerations, especially those of historical development, research activities, theory buildings, methodologies and techniques, professionalization and the practice fields, and the future prospects of social pedagogy.The analysis showed that the historical roots and theoretical foundations of social pedagogical think- ing and action are very similar in Finland and Sweden but the position of social pedagogy  as an academic discipline  as well as a field of practice is partly different. Since social pedagogy has not been acknowl- edged as an academic discipline in Sweden, its outlook as a field of practice is on shaky ground, while in Finland the future of social pedagogy as an academic discipline  is uncertain because the social-peda- gogical know-how based on academic education is not well known and has not found general acceptance in the field’s practice.The analysis showed that the historical roots and theoretical foundations of social pedagogical thinking and action are very similar in Finland and Sweden but the position of social pedagogy as an academic discipline as well as a

  12. A Narrow and Highly Significant Linkage Signal for Severe Bipolar Disorder in the Chromosome 5q33 Region in Latin American Pedigrees

    Science.gov (United States)

    Jasinska, A.J.; Service, S.; Jawaheer, D.; DeYoung, J.; Levinson, M.; Zhang, Z.; Kremeyer, B.; Muller, H.; Aldana, I.; Garcia, J.; Restrepo, G.; Lopez, C.; Palacio, C.; Duque, C.; Parra, M.; Vega, J.; Ortiz, D.; Bedoya, G.; Mathews, C.; Davanzo, P.; Fournier, E.; Bejarano, J.; Ramirez, M.; Ortiz, C. Araya; Araya, X.; Molina, J.; Sabatti, C.; Reus, V.; Ospina, J.; Macaya, G.; Ruiz-Linares, A.; Freimer, N.B.

    2016-01-01

    We previously reported linkage of bipolar disorder to 5q33-q34 in families from two closely related population isolates, the Central Valley of Costa Rica (CVCR) and Antioquia, Colombia (CO). Here we present follow up results from fine-scale mapping in large CVCR and CO families segregating severe bipolar disorder, BP-I, and in 343 population trios/duos from CVCR and CO. Employing densely spaced SNPs to fine map the prior linkage peak region increases linkage evidence and clarifies the position of the putative BP-I locus. We performed two-point linkage analysis with 1134 SNPs in an approximately 9 Mb region between markers D5S410 and D5S422. Combining pedigrees from CVCR and CO yields a LOD score of 4.9 at SNP rs10035961. Two other SNPs (rs7721142 and rs1422795) within the same 94 kb region also displayed LOD scores greater than 4. This linkage peak coincides with our prior microsatellite results and suggests a narrowed BP-I susceptibility regions in these families. To investigate if the locus implicated in the familial form of BP-I also contributes to disease risk in the population, we followed up the family results with association analysis in duo and trio samples, obtaining signals within 2 Mb of the peak linkage signal in the pedigrees; rs12523547 and rs267015 (P = 0.00004 and 0.00016, respectively) in the CO sample and rs244960 in the CVCR sample and the combined sample, with P = 0.00032 and 0.00016, respectively. It remains unclear whether these association results reflect the same locus contributing to BP susceptibility within the extended pedigrees. PMID:19319892

  13. Pedigree-based estimation of covariance between dominance deviations and additive genetic effects in closed rabbit lines considering inbreeding and using a computationally simpler equivalent model.

    Science.gov (United States)

    Fernández, E N; Legarra, A; Martínez, R; Sánchez, J P; Baselga, M

    2017-06-01

    Inbreeding generates covariances between additive and dominance effects (breeding values and dominance deviations). In this work, we developed and applied models for estimation of dominance and additive genetic variances and their covariance, a model that we call "full dominance," from pedigree and phenotypic data. Estimates with this model such as presented here are very scarce both in livestock and in wild genetics. First, we estimated pedigree-based condensed probabilities of identity using recursion. Second, we developed an equivalent linear model in which variance components can be estimated using closed-form algorithms such as REML or Gibbs sampling and existing software. Third, we present a new method to refer the estimated variance components to meaningful parameters in a particular population, i.e., final partially inbred generations as opposed to outbred base populations. We applied these developments to three closed rabbit lines (A, V and H) selected for number of weaned at the Polytechnic University of Valencia. Pedigree and phenotypes are complete and span 43, 39 and 14 generations, respectively. Estimates of broad-sense heritability are 0.07, 0.07 and 0.05 at the base versus 0.07, 0.07 and 0.09 in the final generations. Narrow-sense heritability estimates are 0.06, 0.06 and 0.02 at the base versus 0.04, 0.04 and 0.01 at the final generations. There is also a reduction in the genotypic variance due to the negative additive-dominance correlation. Thus, the contribution of dominance variation is fairly large and increases with inbreeding and (over)compensates for the loss in additive variation. In addition, estimates of the additive-dominance correlation are -0.37, -0.31 and 0.00, in agreement with the few published estimates and theoretical considerations. © 2017 Blackwell Verlag GmbH.

  14. Late-Holocene Climate Change and Human Impact; Palaeoecological Evidence From Peat Deposits in Sweden and Germany

    Science.gov (United States)

    van der Linden, M.; van Geel, B.

    2006-12-01

    With the aim of investigating the effects of climate change and human impact on vegetation and carbon accumulation, we took peat cores of ca. 1 meter depth from four raised bogs situated on a North-South transect, at intervals of c. 500 km, Umeå in Sweden to Angermünde in northern Germany. A number of analyses were conducted (plant macrofossils, pollen/non-pollen microfossils, colorimetric humification, carbon/nitrogen ratios, bulk densities, loss on ignition), and 14C wiggle-match dating was applied to obtain a fine-resolution chronology. The cores from the northern and southern site encompass ca. 1000 years of vegetation history, showing evidence for the end of the Medieval Warm Period (MWP), the Little Ice Age (LIA) and the twentieth century warming. The middle Swedish and German sites are high resolution records of the last 400 years. The end of the MWP and the cooling at the start of the LIA are reflected by a decline in thermophilous tree species. Changes in the macrofossil composition may also represent changes in climate. Shifts in Sphagnum composition, the dominant peat former, reflect changes in precipitation. Evidence for wet conditions and increased carbon accumulation is found during the Little Ice Age. Human activities affected the peat bog and the surrounding vegetation. Sweden suffered many wars during the 16^{th} and 17^{th} century, which caused a decline in population density. Diseases such as the plague and famines caused by crop failures fastened the population decrease. As a consequence, agricultural land was abandoned, resulting in reforestation by Betula. Later, in the modern part of the records, land-use change and planting of trees comprised the major regional vegetation changes. In the southern site, human activities (drainage to facilitate peat cutting) affected the raised bog itself. A part of the peat archive was lost owing to secondary decomposition which resulted in very low carbon accumulation.

  15. Climate in Sweden during the past millennium - Evidence from proxy data, instrumental data and model simulations

    Energy Technology Data Exchange (ETDEWEB)

    Moberg, Anders; Gouirand, Isabelle; Schoning, Kristian; Wohlfarth, Barbara [Stockholm Univ. (Sweden). Dept. of Physical Geography and Quaternary Geology; Kjellstroem, Erik; Rummukainen, Markku [Swedish Meteorological and Hydrological Inst., Norrkoeping (Sweden). Rossby Centre; Jong, Rixt de [Lund Univ. (Sweden). Dept. of Quaternary Geology; Linderholm, Hans [Goeteborg Univ. (Sweden). Dept. of Earth Sciences; Zorita, Eduardo [GKSS Research Centre, Geesthacht (Germany)

    2006-12-15

    Knowledge about climatic variations is essential for SKB in its safety assessments of a geological repository for spent nuclear waste. There is therefore a need for information about possible future climatic variations under a range of possible climatic states. However, predictions of future climate in any deterministic sense are still beyond our reach. We can, nevertheless, try to estimate the magnitude of future climate variability and change due to natural forcing factors, by means of inferences drawn from natural climate variability in the past. Indeed, the climate of the future will be shaped by the sum of natural and anthropogenic climate forcing, as well as the internal climate variability. The aim here is to review and analyse the knowledge about Swedish climate variability, essentially during the past millennium. Available climate proxy data and long instrumental records provide empirical information on past climatic changes. We also demonstrate how climate modelling can be used to extend such knowledge. We use output from a global climate model driven with reconstructed radiative forcings (solar, volcanic and greenhouse gas forcing), to provide boundary conditions for a regional climate model. The regional model provides more details of the climate than the global model, and we develop a simulated climate history for Sweden that is complete in time and space and physically consistent. We use output from a regional model simulation for long periods in the last millennium, to study annual mean temperature, precipitation and runoff for the northern and southern parts of Sweden. The simulated data are used to place corresponding instrumental records for the 20th century into a plausible historical perspective. We also use output from the regional model to study how the frequency distribution of the daily temperature, precipitation, runoff and evaporation at Forsmark and Oskarshamn could have varied between unusually warm and cold 30-year periods during the

  16. Climate in Sweden during the past millennium - Evidence from proxy data, instrumental data and model simulations

    International Nuclear Information System (INIS)

    Moberg, Anders; Gouirand, Isabelle; Schoning, Kristian; Wohlfarth, Barbara

    2006-12-01

    Knowledge about climatic variations is essential for SKB in its safety assessments of a geological repository for spent nuclear waste. There is therefore a need for information about possible future climatic variations under a range of possible climatic states. However, predictions of future climate in any deterministic sense are still beyond our reach. We can, nevertheless, try to estimate the magnitude of future climate variability and change due to natural forcing factors, by means of inferences drawn from natural climate variability in the past. Indeed, the climate of the future will be shaped by the sum of natural and anthropogenic climate forcing, as well as the internal climate variability. The aim here is to review and analyse the knowledge about Swedish climate variability, essentially during the past millennium. Available climate proxy data and long instrumental records provide empirical information on past climatic changes. We also demonstrate how climate modelling can be used to extend such knowledge. We use output from a global climate model driven with reconstructed radiative forcings (solar, volcanic and greenhouse gas forcing), to provide boundary conditions for a regional climate model. The regional model provides more details of the climate than the global model, and we develop a simulated climate history for Sweden that is complete in time and space and physically consistent. We use output from a regional model simulation for long periods in the last millennium, to study annual mean temperature, precipitation and runoff for the northern and southern parts of Sweden. The simulated data are used to place corresponding instrumental records for the 20th century into a plausible historical perspective. We also use output from the regional model to study how the frequency distribution of the daily temperature, precipitation, runoff and evaporation at Forsmark and Oskarshamn could have varied between unusually warm and cold 30-year periods during the

  17. Veganism as status passage: the process of becoming a vegan among youths in Sweden.

    Science.gov (United States)

    Larsson, Christel L; Rönnlund, Ulla; Johansson, Gunnar; Dahlgren, Lars

    2003-08-01

    In a town in northern Sweden, 3.3% of the 15-year-old adolescents were vegans in 1996. This study describes the process of becoming a vegan among adolescents and interprets the informants' descriptions by constructing categories, which later on were related to relevant theories. Group interviews were conducted with three vegans and in-depth interviews were performed with three other vegan adolescents. The methodology was grounded theory and the adolescents' perceptions were analyzed in the framework of symbolic interactionism. Three types of vegans were identified: the Conformed Vegan, the Organized Vegan, and the Individualistic Vegan. The decision to become a vegan was reported to be influenced by perceived internal reasons such as ethics, health, distaste for meat, and preference for vegetarian food. In addition, friends, family, school, media, and music influenced the decision to become a vegan. The perceived consequences of becoming a vegan were positive as well as negative and differed between the three types of vegans. Veganism as a new type of status passage with specific characteristics was illustrated. No modifications or new properties were discovered that add to the theory of status passage which indicates that the general model is applicable also in a vegan context.

  18. An ABCA1 truncation shows no dominant negative effect in a familial hypoalphalipoproteinemia pedigree with three ABCA1 mutations

    Energy Technology Data Exchange (ETDEWEB)

    Sorrenson, Brie; Suetani, Rachel J. [Department of Biochemistry, University of Otago, Dunedin (New Zealand); Bickley, Vivienne M.; George, Peter M. [Clinical Biochemistry, Canterbury Health Laboratories, Christchurch (New Zealand); Williams, Michael J.A. [Department of Medicine, University of Otago, Dunedin (New Zealand); Scott, Russell S. [Lipid and Diabetes Research Group, Christchurch Hospital (New Zealand); McCormick, Sally P.A., E-mail: sally.mccormick@otago.ac.nz [Department of Biochemistry, University of Otago, Dunedin (New Zealand)

    2011-06-10

    Highlights: {yields} Characterisation of an ABCA1 truncation mutant, C978fsX988, in a pedigree with three ABCA1 mutations. {yields} Functional analysis of C978fsX988 in patient fibroblasts and HEK 293 cells shows no cholesterol efflux function. {yields} Allele-specific quantification shows C978fsX988 not expressed at mRNA level in fibroblasts. {yields} Unlike other ABCA1 truncations, C978fsX988 mutant shows no dominant negative effect at mRNA or protein level. -- Abstract: The ATP binding cassette transporter (ABCA1) A1 is a key determinant of circulating high density lipoprotein cholesterol (HDL-C) levels. Mutations in ABCA1 are a major genetic contributor to low HDL-C levels within the general population. Following the finding of three different ABCA1 mutations, p.C978fsX988, p.T1512M and p.N1800H in a subject with hypoalphalipoproteinemia, we aimed to establish whether the p.C978fsX988 truncation exerted a dominant negative effect on the full-length ABCA1 alleles within family members as has been reported for other ABCA1 truncations. Characterisation of the p.C978fsX988 mutant in transfected HEK 293 cells showed it to be expressed as a GFP fusion protein but lacking in cholesterol efflux function. This was in keeping with results from cholesterol efflux assays in the fibroblasts of p.C978fsX988 carriers which also showed impaired efflux. Allele- specific quantification of p.C978fsX988 mRNA and analysis of ABCA1 protein levels in the fibroblasts of p.C978fsX988 heterozygotes showed negligible levels of mRNA and protein expression. There was no evidence of a dominant negative effect on wildtype or p.N1800H protein levels. We conclude that in the case of the p.C978fsX988 truncated mutant a lack of expression precludes it from having a dominant negative effect.

  19. QTL mapping in white spruce: gene maps and genomic regions underlying adaptive traits across pedigrees, years and environments

    Science.gov (United States)

    2011-01-01

    Background The genomic architecture of bud phenology and height growth remains poorly known in most forest trees. In non model species, QTL studies have shown limited application because most often QTL data could not be validated from one experiment to another. The aim of our study was to overcome this limitation by basing QTL detection on the construction of genetic maps highly-enriched in gene markers, and by assessing QTLs across pedigrees, years, and environments. Results Four saturated individual linkage maps representing two unrelated mapping populations of 260 and 500 clonally replicated progeny were assembled from 471 to 570 markers, including from 283 to 451 gene SNPs obtained using a multiplexed genotyping assay. Thence, a composite linkage map was assembled with 836 gene markers. For individual linkage maps, a total of 33 distinct quantitative trait loci (QTLs) were observed for bud flush, 52 for bud set, and 52 for height growth. For the composite map, the corresponding numbers of QTL clusters were 11, 13, and 10. About 20% of QTLs were replicated between the two mapping populations and nearly 50% revealed spatial and/or temporal stability. Three to four occurrences of overlapping QTLs between characters were noted, indicating regions with potential pleiotropic effects. Moreover, some of the genes involved in the QTLs were also underlined by recent genome scans or expression profile studies. Overall, the proportion of phenotypic variance explained by each QTL ranged from 3.0 to 16.4% for bud flush, from 2.7 to 22.2% for bud set, and from 2.5 to 10.5% for height growth. Up to 70% of the total character variance could be accounted for by QTLs for bud flush or bud set, and up to 59% for height growth. Conclusions This study provides a basic understanding of the genomic architecture related to bud flush, bud set, and height growth in a conifer species, and a useful indicator to compare with Angiosperms. It will serve as a basic reference to functional and

  20. Concentrations of base cations, phosphorous and nitrogen in tree stumps in Sweden, Finland and Denmark; Halter av baskatjoner, fosfor och kvaeve i stubbar i Sverige, Finland och Danmark

    Energy Technology Data Exchange (ETDEWEB)

    Hellsten, Sofie; Waengberg, Ingvar (The Swedish Environmental Research Institute Ltd., Stockholm (Sweden)); Helmisaari, Heljae-Sisko; Kaakinen, Seija; Kukkola, Mikko; Saarsalmi, Anna (Metla, Vantaa (Finland)); Melin, Ylva; Petersson, Hans (Swedish Univ. of Agriculture, Umeaa (Sweden)); Skovsgaard, Jens Peter (Forest and Landscape Denmark, Univ. of Copenhagen, Hoersholm (Denmark)); Akselsson, Cecilia (Lunds Univ., Lund (Sweden))

    2009-05-15

    Stump removal is becoming increasingly important in as demand for renewable energy is increasing. Nutrient concentrations in stumps are applied when evaluating the environmental effect of stump removal on acidification and nutrient balances in forest soil. The objectives of this study was to evaluate concentrations of nutrients in stumps in Sweden, Finland and Denmark, and to evaluate how nutrient concentrations vary with site characteristics, stand age and deposition level. Concentrations of N, P, Ca, K, Mg and Na in spruce, pine and birch stumps were assessed in eight sites across Scandinavia. The results of this study indicate that the concentration of nutrients are higher in birch stumps compared with spruce and pine. In Sweden and Finland, the nutrient concentrations were generally higher in the southern sites compared with northern sites in the country, except for P. Nutrient concentrations were significantly higher in the bark of the stump and the roots compared to the wood for all nutrients. Furthermore nutrients concentration increased significantly with decreasing root diameter. In Jaedraaas, Sweden, nutrient concentration of N, K, Mg and P in pine decreased with age of the stump harvested tree, for stumps < 65 years. This relation was not evident for other age spans or sites. Further studies are needed to provide a broader picture of how the nutrient concentrations vary with site characteristics, stand age and forestry management to get a better foundation when setting up recommendations for stump removal