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Sample records for normalised resistance interpretation

  1. Rules of Normalisation and their Importance for Interpretation of Systems of Optimal Taxation

    DEFF Research Database (Denmark)

    Munk, Knud Jørgen

    representation of the general equilibrium conditions the rules of normalisation in standard optimal tax models. This allows us to provide an intuitive explanation of what determines the optimal tax system. Finally, we review a number of examples where lack of precision with respect to normalisation in otherwise...... important contributions to the literature on optimal taxation has given rise to misinterpretations of of analytical results....

  2. Bariatric surgery in morbidly obese insulin resistant humans normalises insulin signalling but not insulin-stimulated glucose disposal.

    Directory of Open Access Journals (Sweden)

    Mimi Z Chen

    Full Text Available Weight-loss after bariatric surgery improves insulin sensitivity, but the underlying molecular mechanism is not clear. To ascertain the effect of bariatric surgery on insulin signalling, we examined glucose disposal and Akt activation in morbidly obese volunteers before and after Roux-en-Y gastric bypass surgery (RYGB, and compared this to lean volunteers.The hyperinsulinaemic euglycaemic clamp, at five infusion rates, was used to determine glucose disposal rates (GDR in eight morbidly obese (body mass index, BMI=47.3 ± 2.2 kg/m(2 patients, before and after RYGB, and in eight lean volunteers (BMI=20.7 ± 0.7 kg/m2. Biopsies of brachioradialis muscle, taken at fasting and insulin concentrations that induced half-maximal (GDR50 and maximal (GDR100 GDR in each subject, were used to examine the phosphorylation of Akt-Thr308, Akt-473, and pras40, in vivo biomarkers for Akt activity.Pre-operatively, insulin-stimulated GDR was lower in the obese compared to the lean individuals (P<0.001. Weight-loss of 29.9 ± 4 kg after surgery significantly improved GDR50 (P=0.004 but not GDR100 (P=0.3. These subjects still remained significantly more insulin resistant than the lean individuals (p<0.001. Weight loss increased insulin-stimulated skeletal muscle Akt-Thr308 and Akt-Ser473 phosphorylation, P=0.02 and P=0.03 respectively (MANCOVA, and Akt activity towards the substrate PRAS40 (P=0.003, MANCOVA, and in contrast to GDR, were fully normalised after the surgery (obese vs lean, P=0.6, P=0.35, P=0.46, respectively.Our data show that although Akt activity substantially improved after surgery, it did not lead to a full restoration of insulin-stimulated glucose disposal. This suggests that a major defect downstream of, or parallel to, Akt signalling remains after significant weight-loss.

  3. Normalising corporate counterinsurgency: Engineering consent, managing resistance and greening destruction around the Hambach coal mine and beyond

    NARCIS (Netherlands)

    Dunlap, A.A.

    2018-01-01

    The German Rhineland is home to the world's largest opencast lignite coal mine and human-made hole – the Hambach mine. Over the last seven years, RWE, the mine operator, has faced an increase in militant resistance, culminating in the occupation of the Hambacher Forest and acts of civil disobedience

  4. Normalising convenience food?

    DEFF Research Database (Denmark)

    Halkier, Bente

    2017-01-01

    The construction of convenience food as a social and cultural category for food provisioning, cooking and eating seems to slide between or across understandings of what is considered “proper food” in the existing discourses in everyday life and media. This article sheds light upon some...... of the social and cultural normativities around convenience food by describing the ways in which convenience food forms part of the daily life of young Danes. Theoretically, the article is based on a practice theoretical perspective. Empirically, the article builds upon a qualitative research project on food...... habits among Danes aged 20–25. The article presents two types of empirical patterns. The first types of patterns are the degree to which and the different ways in which convenience food is normalised to use among the young Danes. The second types of patterns are the normative places of convenient food...

  5. Supervised Object Class Colour Normalisation

    DEFF Research Database (Denmark)

    Riabchenko, Ekatarina; Lankinen, Jukka; Buch, Anders Glent

    2013-01-01

    . In this work, we develop a such colour normalisation technique, where true colours are not important per se but where examples of same classes have photometrically consistent appearance. This is achieved by supervised estimation of a class specic canonical colour space where the examples have minimal variation......Colour is an important cue in many applications of computer vision and image processing, but robust usage often requires estimation of the unknown illuminant colour. Usually, to obtain images invariant to the illumination conditions under which they were taken, color normalisation is used...... in their colours. We demonstrate the effectiveness of our method with qualitative and quantitative examples from the Caltech-101 data set and a real application of 3D pose estimation for robot grasping....

  6. Nuclear power 1984: Progressive normalisation

    International Nuclear Information System (INIS)

    Popp, M.

    1984-01-01

    The peaceful use of nuclear power is being integrated into the overall concept of a safe long-term power supply in West Germany. The progress of normalisation is shown particularly in the takeover of all stations of the nuclear fuel circuit by the economy, with the exception of the final storage of radioactive waste, which is the responsibility of the West German Government. Normalisation also means the withdrawal of the state from financing projects after completion of the two prototypes SNR-300 and THTR-300 and the German uranium enrichment plant. The state will, however, support future research and development projects in the nuclear field. The expansion of nuclear power capacity is at present being slowed down by the state of the economy, i.e. only nuclear power projects being built are proceeding. (orig./HP) [de

  7. Infinitary Combinatory Reduction Systems: Normalising Reduction Strategies

    NARCIS (Netherlands)

    Ketema, J.; Simonsen, Jakob Grue

    2010-01-01

    We study normalising reduction strategies for infinitary Combinatory Reduction Systems (iCRSs). We prove that all fair, outermost-fair, and needed-fair strategies are normalising for orthogonal, fully-extended iCRSs. These facts properly generalise a number of results on normalising strategies in

  8. Ensemble Classifiers for Predicting HIV-1 Resistance from Three Rule-Based Genotypic Resistance Interpretation Systems.

    Science.gov (United States)

    Raposo, Letícia M; Nobre, Flavio F

    2017-08-30

    Resistance to antiretrovirals (ARVs) is a major problem faced by HIV-infected individuals. Different rule-based algorithms were developed to infer HIV-1 susceptibility to antiretrovirals from genotypic data. However, there is discordance between them, resulting in difficulties for clinical decisions about which treatment to use. Here, we developed ensemble classifiers integrating three interpretation algorithms: Agence Nationale de Recherche sur le SIDA (ANRS), Rega, and the genotypic resistance interpretation system from Stanford HIV Drug Resistance Database (HIVdb). Three approaches were applied to develop a classifier with a single resistance profile: stacked generalization, a simple plurality vote scheme and the selection of the interpretation system with the best performance. The strategies were compared with the Friedman's test and the performance of the classifiers was evaluated using the F-measure, sensitivity and specificity values. We found that the three strategies had similar performances for the selected antiretrovirals. For some cases, the stacking technique with naïve Bayes as the learning algorithm showed a statistically superior F-measure. This study demonstrates that ensemble classifiers can be an alternative tool for clinical decision-making since they provide a single resistance profile from the most commonly used resistance interpretation systems.

  9. Queer Literature in Spain: Pathways to Normalisation

    Directory of Open Access Journals (Sweden)

    Martínez-Expósito, Alfredo

    2013-06-01

    Full Text Available More than any other, the idea of normalisation has provoked deep divisions within queer activism both at a philosophical and also at a political level. At the root of these divisions lies the irreconcilable divergence between an agenda for social change, which advocates the need for society to accept all sexual behaviours and identities as normal, and an approach of radical resistance against some social structures that can only offer a bourgeois and conformist normalisation. Literary fiction and homo-gay-queer themed cinema have explored these and other sides of the idea of normalisation and have thus contributed to the taking of decisive steps: from the poetics of transgression towards the poetics of celebration and social transformation. In this paper we examine two of these literary normalisation strategies: the use of humour and the proliferation of discursive perspectives both in the cinema and in narrative fiction during the last decades.Más quizá que ninguna otra, la idea de normalización ha provocado profundas divisiones en el seno del activismo queer, tanto a nivel filosófico/conceptual como a nivel de estrategia política. En el origen de estas divisiones se encuentra la irreconciliable divergencia entre una agenda de cambio social, que propugna la necesidad de que la sociedad acepte como normales todas las conductas e identidades sexuales, y un planteamiento de resistencia radical ante unas estructuras sociales que sólo pueden ofrecer una normalización burguesa y acomodaticia. La literatura de ficción y el cine de temática homo-gay-queer han explorado éstas y otras facetas de la idea de normalización, contribuyendo así a dar pasos decisivos desde las poéticas de la transgresión hacia poéticas de la celebración y transformación social. En esta presentación se exploran dos de estas estrategias de normalización literaria: el uso del humor y la proliferación de perspectivas discursivas en el cine y la narrativa de

  10. Polymyxin susceptibility testing, interpretative breakpoints and resistance mechanisms: An update.

    Science.gov (United States)

    Bakthavatchalam, Yamuna Devi; Pragasam, Agila Kumari; Biswas, Indranil; Veeraraghavan, Balaji

    2018-03-01

    Emerging multidrug-resistant (MDR) nosocomial pathogens are a great threat. Polymyxins, an old class of cationic polypeptide antibiotic, are considered as last-resort drugs in treating infections caused by MDR Gram-negative bacteria. Increased use of polymyxins in treating critically ill patients necessitates routine polymyxin susceptibility testing. However, susceptibility testing both of colistin and polymyxin B (PMB) is challenging. In this review, currently available susceptibility testing methods are briefly discussed. The multicomponent composition of colistin and PMB significantly influences susceptibility testing. In addition, poor diffusion in the agar medium, adsorption to microtitre plates and the synergistic effect of the surfactant polysorbate 80 with polymyxins have a great impact on the performance of susceptibility testing methods This review also describes recently identified chromosomal resistance mechanisms, including modification of lipopolysaccharide (LPS) with 4-amino-4-deoxy-l-arabinose (L-Ara4-N) and phosphoethanolamine (pEtN) resulting in alteration of the negative charge, as well as the plasmid-mediated colistin resistance determinants mcr-1, mcr-1.2, mcr-2 and mcr-3. Copyright © 2017 International Society for Chemotherapy of Infection and Cancer. Published by Elsevier Ltd. All rights reserved.

  11. Modeling and Inversion Methods for the Interpretation of Resistivity Logging Tool Response

    NARCIS (Netherlands)

    Anderson, B.I.

    2001-01-01

    The electrical resistivity measured by well logging tools is one of the most important rock parameters for indicating the amount of hydrocarbons present in a reservoir. The main interpretation challenge is to invert the measured data, solving for the true resistivity values in each zone of a

  12. Attitudes to Normalisation and Inclusive Education

    Science.gov (United States)

    Sanagi, Tomomi

    2016-01-01

    The purpose of this paper was to clarify the features of teachers' image on normalisation and inclusive education. The participants of the study were both mainstream teachers and special teachers. One hundred and thirty-eight questionnaires were analysed. (1) Teachers completed the questionnaire of SD (semantic differential) images on…

  13. The stories we tell: qualitative research interviews, talking technologies and the 'normalisation' of life with HIV.

    Science.gov (United States)

    Mazanderani, Fadhila; Paparini, Sara

    2015-04-01

    Since the earliest days of the HIV/AIDS epidemic, talking about the virus has been a key way affected communities have challenged the fear and discrimination directed against them and pressed for urgent medical and political attention. Today, HIV/AIDS is one of the most prolifically and intimately documented of all health conditions, with entrenched infrastructures, practices and technologies--what Vinh-Kim Nguyen has dubbed 'confessional technologies'--aimed at encouraging those affected to share their experiences. Among these technologies, we argue, is the semi-structured interview: the principal methodology used in qualitative social science research focused on patient experiences. Taking the performative nature of the research interview as a talking technology seriously has epistemological implications not merely for how we interpret interview data, but also for how we understand the role of research interviews in the enactment of 'life with HIV'. This paper focuses on one crucial aspect of this enactment: the contemporary 'normalisation' of HIV as 'just another' chronic condition--a process taking place at the level of individual subjectivities, social identities, clinical practices and global health policy, and of which social science research is a vital part. Through an analysis of 76 interviews conducted in London (2009-10), we examine tensions in the experiential narratives of individuals living with HIV in which life with the virus is framed as 'normal', yet where this 'normality' is beset with contradictions and ambiguities. Rather than viewing these as a reflection of resistances to or failures of the enactment of HIV as 'normal', we argue that, insofar as these contradictions are generated by the research interview as a distinct 'talking technology', they emerge as crucial to the normative (re)production of what counts as 'living with HIV' (in the UK) and are an inherent part of the broader performative 'normalisation' of the virus. Copyright © 2015

  14. Interpretation of hole-to-surface resistivity measurements at Yucca Mountain, Nevada Test Site

    International Nuclear Information System (INIS)

    Daniels, J.J.; Scott, J.H.

    1981-01-01

    Hole-to-surface resistivity measurements at Yucca Mountain indicate the presence of many near-surface geologic inhomogeneities, with no definite indication of deep structural features. A resistive anomaly near drill hole UE25a-6 is interpreted as a thin, vertical, resistive body that nearly intersects the surface, and may be caused by a silicified, or calcified, fracture zone. A resistive anomaly near hole UE25a-7 is probably caused by a near surface, horizontal, lens-shaped body that may represent a devitrified zone in the Tiva Canyon Member. Many conductive anomalies were detected to the southwest of hole UE25a-4. However, these anomalies are interpreted to be caused by variations in the thickness of the surface alluvium

  15. Comparison of HIV-1 genotypic resistance test interpretation systems in predicting virological outcomes over time

    NARCIS (Netherlands)

    D. Frentz (Dineke); C.A.B. Boucher (Charles); M. Assel (Matthias); A. de Luca (Andrea); M. Fabbiani (Massimiliano); F. Incardona (Francesca); P. Libin (Pieter); N. Manca (Nino); V. Müller (Viktor); B.O. Nualláin (Breanndán); R. Paredes (Roger); M. Prosperi (Mattia); E. Quiros-Roldan (Eugenia); L. Ruiz (Lidia); P.M.A. Sloot (Peter); C. Torti (Carlo); A.M. Vandamme (Anne Mieke); K. Laethem (Kristel); M. Zazzi (Maurizio); D.A.M.C. van de Vijver (David)

    2010-01-01

    textabstractBackground: Several decision support systems have been developed to interpret HIV-1 drug resistance genotyping results. This study compares the ability of the most commonly used systems (ANRS, Rega, and Stanford's HIVdb) to predict virological outcome at 12, 24, and 48 weeks.

  16. Improved Geologic Interpretation of Non-invasive Electrical Resistivity Imaging from In-situ Samples

    Science.gov (United States)

    Mucelli, A.; Aborn, L.; Jacob, R.; Malusis, M.; Evans, J.

    2016-12-01

    Non-invasive geophysical techniques are useful in characterizing the subsurface geology without disturbing the environment, however, the ability to interpret the subsurface is enhanced by invasive work. Since geologic materials have electrical resistivity values it allows for a geologic interpretation to be made based on variations of electrical resistivity measured by electrical resistivity imaging (ERI). This study focuses on the pre-characterization of the geologic subsurface from ERI collected adjacent to the Montandon Marsh, a wetland located near Lewisburg, PA within the West Branch of the Susquehanna River watershed. The previous invasive data, boreholes, indicate that the subsurface consists of limestone and shale bedrock overlain with sand and gravel deposits from glacial outwash and aeolian processes. The objective is to improve our understanding of the subsurface at this long-term hydrologic research site by using excavation results, specifically observed variations in geologic materials and electrical resistivity laboratory testing of subsurface samples. The pre-excavation ERI indicated that the shallow-most geologic material had a resistivity value of 100-500 ohm-m. In comparison, the laboratory testing indicated the shallow-most material had the same range of electrical resistivity values depending on saturation levels. The ERI also showed that there was an electrically conductive material, 7 to 70 ohm-m, that was interpreted to be clay and agreed with borehole data, however, the excavation revealed that at this depth range the geologic material varied from stratified clay to clay with cobbles to weathered residual clay. Excavation revealed that the subtle variations in the electrical conductive material corresponded well with the variations in the geologic material. We will use these results to reinterpret previously collected ERI data from the entire long-term research site.

  17. Antimicrobial resistance 1979-2009 at Karolinska hospital, Sweden: normalized resistance interpretation during a 30-year follow-up on Staphylococcus aureus and Escherichia coli resistance development.

    Science.gov (United States)

    Kronvall, Göran

    2010-09-01

    To utilize a material of inhibition zone diameter measurements from disc diffusion susceptibility tests between 1979 and 2009, an objective setting of epidemiological breakpoints was necessary because of methodological changes. Normalized resistance interpretation (NRI) met this need and was applied to zone diameter histograms for Staphylococcus aureus and Escherichia coli isolates. The results confirmed a slow resistance development as seen in Northern countries. The S. aureus resistance levels for erythromycin, clindamycin and fusidic acid in 2009 were 3.2%, 1.8% and 1.4% with denominator correction. A rise in resistance to four antimicrobials in 1983 was probably because of a spread of resistant Methicillin Susceptible Staphylococcus Aureus (MSSA). For E. coli, the denominator-corrected resistance levels in 2009 were 27% for ampicillin, around 3% for third-generation cephalosporins, 0.1% for imipenem, 2.5% for gentamicin, 19% for trimethoprim, 4.5% for co-trimoxazole, 1.2% for nitrofurantoin and 9% for ciprofloxacin. The temporal trends showed a rise in fluoroquinolone resistance from 1993, a parallel increase in gentamicin resistance, a substantial increase in trimethoprim and sulphonamide resistance in spite of decreased consumption, and a steady rise in ampicillin resistance from a constant level before 1989. A short review of global resistance surveillance studies is included.

  18. Analysis and interpretation of electrical resistivity tomography data of alluvial aquifer of Tamanrasset Southern Algeria

    Science.gov (United States)

    Zeddouri, Aziez; Elkheir, Abderrahmane Ben; Hadj-Said, Samia; Taupin, Jean-Denis; Leduc, Christian; Patris, Nicholas

    2018-05-01

    A groundwater exploration work in the Tamanrasset region in southern Algeria was started in August 2016 to assess the water reserves in the hydrogeological system related to the Oued Tamanrasset underflow water table which overcomes a volcanic basement. Five (05) electrical resistivity tomography (ERT) surveys were conducted in Tamanrasset area by using ABEM Terrameter LS system. the low electrical contrast between wet alluvium and water saturated alterites makes difficult the electrical response interpretation. to overcome the difficulties of interpretation of ERT profiles, field investigations, laboratory tests and software simulations, were carried out in order to clearly identify the structure of the hydrogeological system. The experimental investigation of the electrical characteristics of the alluvium as a function of water saturation was carried by the use of two devices (Wenner α and Schlumberger). Samples true resistivity values varies between 50 Ω.m for a 100% saturated sample and 1250 Ω.m for a 25% saturation sample. The interpretation of the measurements by the RES2DINV software made it possible to give 2D images of the subsoil up to a depth of 50 m. the electrical contrast between the bedrock and the overlying formations made it possible to identify it, however, it was difficult to distinguish alterites from alluvium. A methodology combining piezometric survey, geo-electrical measurements and field observations improves the interpretation of electrical tomography profiles and the application of the ERT method for accurate characterization of water resources in the Tamanrasset region.

  19. Uranium deposit interpretation based on resistivity and induced polarization data in Rabau hulu sector

    International Nuclear Information System (INIS)

    Dwi Haryanto; Bambang Soetopo; Adhika Junara Karunianto; Supriyanto

    2015-01-01

    Rabau Hulu area, Kalan, Kalimantan Barat is a potential area of uranium that has been explored in detail by various methods. Methods of resistivity and induced polarization can be applied in the exploration of uranium deposits in which its mineralization associated with sulphide minerals. Processing, analysis, and interpretation of resistivity and induced polarization data conducted in order to identify the distribution of uranium deposits and lithology of the rocks in the study area. Uranium deposits in the area Rabau Hulu is generally associated with sulphides, tourmaline and contained in favorable rocks. Symptoms of uranium mineralization encountered in other forms of irregular and uneven consists of uraninite, pyrite, chalcopyrite, pyrrhotite, molybdenite, and ilmenite minerals. Data acquisition using dipole-dipole configuration in an area of approximately 36 hectares, 46 lines along ± 425 m. Acquisition of induced polarization frequency domain data which the same points and lines with resistivity data. Data processing produces resistivity and metal factor values and subsequently made two-dimensional section. Determination of resistivity and induced polarization are done by correlated boreholes data with the results of data processing. Resistivity of uranium deposits zone worth less than 2,000 Ωm and the value of metal factor greater than 90 mho/m. Uranium deposit zone is expanding along with the depth. Uranium deposits distribution trending Southwestern-Northeast and shaped lens. (author)

  20. Random forest meteorological normalisation models for Swiss PM10 trend analysis

    Science.gov (United States)

    Grange, Stuart K.; Carslaw, David C.; Lewis, Alastair C.; Boleti, Eirini; Hueglin, Christoph

    2018-05-01

    Meteorological normalisation is a technique which accounts for changes in meteorology over time in an air quality time series. Controlling for such changes helps support robust trend analysis because there is more certainty that the observed trends are due to changes in emissions or chemistry, not changes in meteorology. Predictive random forest models (RF; a decision tree machine learning technique) were grown for 31 air quality monitoring sites in Switzerland using surface meteorological, synoptic scale, boundary layer height, and time variables to explain daily PM10 concentrations. The RF models were used to calculate meteorologically normalised trends which were formally tested and evaluated using the Theil-Sen estimator. Between 1997 and 2016, significantly decreasing normalised PM10 trends ranged between -0.09 and -1.16 µg m-3 yr-1 with urban traffic sites experiencing the greatest mean decrease in PM10 concentrations at -0.77 µg m-3 yr-1. Similar magnitudes have been reported for normalised PM10 trends for earlier time periods in Switzerland which indicates PM10 concentrations are continuing to decrease at similar rates as in the past. The ability for RF models to be interpreted was leveraged using partial dependence plots to explain the observed trends and relevant physical and chemical processes influencing PM10 concentrations. Notably, two regimes were suggested by the models which cause elevated PM10 concentrations in Switzerland: one related to poor dispersion conditions and a second resulting from high rates of secondary PM generation in deep, photochemically active boundary layers. The RF meteorological normalisation process was found to be robust, user friendly and simple to implement, and readily interpretable which suggests the technique could be useful in many air quality exploratory data analysis situations.

  1. Normalisation: ROI optimal treatment planning - SNDH pattern

    International Nuclear Information System (INIS)

    Shilvat, D.V.; Bhandari, Virendra; Tamane, Chandrashekhar; Pangam, Suresh

    2001-01-01

    Dose precision maximally to the target / ROI (Region of Interest), taking care of tolerance dose of normal tissue is the aim of ideal treatment planning. This goal is achieved with advanced modalities such as, micro MLC, simulator and 3-dimensional treatment planning system. But SNDH PATTERN uses minimum available resources as, ALCYON II Telecobalt unit, CT Scan, MULTIDATA 2-dimensional treatment planning system to their maximum utility and reaches to the required precision, same as that with advance modalities. Among the number of parameters used, 'NORMALISATION TO THE ROI' will achieve the aim of the treatment planning effectively. This is dealing with an example of canal of esophagus modified treatment planning based on SNDH pattern. Results are attractive and self explanatory. By implementing SNDH pattern, the QUALITY INDEX of treatment plan will reach to greater than 90%, with substantial reduction in dose to the vital organs. Aim is to utilize the minimum available resources efficiently to achieve highest possible precision for delivering homogenous dose to ROI while taking care of tolerance dose to vital organs

  2. Technology, normalisation and male sex work.

    Science.gov (United States)

    MacPhail, Catherine; Scott, John; Minichiello, Victor

    2015-01-01

    Technological change, particularly the growth of the Internet and smart phones, has increased the visibility of male escorts, expanded their client base and diversified the range of venues in which male sex work can take place. Specifically, the Internet has relocated some forms of male sex work away from the street and thereby increased market reach, visibility and access and the scope of sex work advertising. Using the online profiles of 257 male sex workers drawn from six of the largest websites advertising male sexual services in Australia, the role of the Internet in facilitating the normalisation of male sex work is discussed. Specifically we examine how engagement with the sex industry has been reconstituted in term of better informed consumer-seller decisions for both clients and sex workers. Rather than being seen as a 'deviant' activity, understood in terms of pathology or criminal activity, male sex work is increasingly presented as an everyday commodity in the market place. In this context, the management of risks associated with sex work has shifted from formalised social control to more informal practices conducted among online communities of clients and sex workers. We discuss the implications for health, legal and welfare responses within an empowerment paradigm.

  3. High- and Low-Load Resistance Training: Interpretation and Practical Application of Current Research Findings.

    Science.gov (United States)

    Fisher, James; Steele, James; Smith, Dave

    2017-03-01

    Our current state of knowledge regarding the load (lighter or heavier) lifted in resistance training programmes that will result in 'optimal' strength and hypertrophic adaptations is unclear. Despite this, position stands and recommendations are made based on, we propose, limited evidence to lift heavier weights. Here we discuss the state of evidence on the impact of load and how it, as a single variable, stimulates adaptations to take place and whether evidence for recommending heavier loads is available, well-defined, currently correctly interpreted or has been overlooked. Areas of discussion include electromyography amplitude, in vivo and in vitro methods of measuring hypertrophy, and motor schema and skill acquisition. The present piece clarifies to trainers and trainees the impact of these variables by discussing interpretation of synchronous and sequential motor unit recruitment and revisiting the size principle, poor agreement between whole-muscle cross-sectional area (CSA) and biopsy-determined changes in myofibril CSA, and neural adaptations around task specificity. Our opinion is that the practical implications of being able to self-select external load include reducing the need for specific facility memberships, motivating older persons or those who might be less confident using heavy loads, and allowing people to undertake home- or field-based resistance training intervention strategies that might ultimately improve exercise adherence.

  4. Normalised flood losses in Europe: 1970-2006

    Science.gov (United States)

    Barredo, J. I.

    2009-02-01

    This paper presents an assessment of normalised flood losses in Europe for the period 1970-2006. Normalisation provides an estimate of the losses that would occur if the floods from the past take place under current societal conditions. Economic losses from floods are the result of both societal and climatological factors. Failing to adjust for time-variant socio-economic factors produces loss amounts that are not directly comparable over time, but rather show an ever-growing trend for purely socio-economic reasons. This study has used available information on flood losses from the Emergency Events Database (EM-DAT) and the Natural Hazards Assessment Network (NATHAN). Following the conceptual approach of previous studies, we normalised flood losses by considering the effects of changes in population, wealth, and inflation at the country level. Furthermore, we removed inter-country price differences by adjusting the losses for purchasing power parities (PPP). We assessed normalised flood losses in 31 European countries. These include the member states of the European Union, Norway, Switzerland, Croatia, and the Former Yugoslav Republic of Macedonia. Results show no detectable sign of human-induced climate change in normalised flood losses in Europe. The observed increase in the original flood losses is mostly driven by societal factors.

  5. Confluence via strong normalisation in an algebraic λ-calculus with rewriting

    Directory of Open Access Journals (Sweden)

    Pablo Buiras

    2012-03-01

    Full Text Available The linear-algebraic lambda-calculus and the algebraic lambda-calculus are untyped lambda-calculi extended with arbitrary linear combinations of terms. The former presents the axioms of linear algebra in the form of a rewrite system, while the latter uses equalities. When given by rewrites, algebraic lambda-calculi are not confluent unless further restrictions are added. We provide a type system for the linear-algebraic lambda-calculus enforcing strong normalisation, which gives back confluence. The type system allows an abstract interpretation in System F.

  6. Normalisation and weighting in life cycle assessment: quo vadis?

    DEFF Research Database (Denmark)

    Pizzol, Massimo; Laurent, Alexis; Sala, Serenella

    2017-01-01

    Purpose: Building on the rhetoric question “quo vadis?” (literally “Where are you going?”), this article critically investigates the state of the art of normalisation and weighting approaches within life cycle assessment. It aims at identifying purposes, current practises, pros and cons, as well...

  7. Interpretation of deep directional resistivity measurements acquired in high-angle and horizontal wells using 3-D inversion

    Science.gov (United States)

    Puzyrev, Vladimir; Torres-Verdín, Carlos; Calo, Victor

    2018-05-01

    The interpretation of resistivity measurements acquired in high-angle and horizontal wells is a critical technical problem in formation evaluation. We develop an efficient parallel 3-D inversion method to estimate the spatial distribution of electrical resistivity in the neighbourhood of a well from deep directional electromagnetic induction measurements. The methodology places no restriction on the spatial distribution of the electrical resistivity around arbitrary well trajectories. The fast forward modelling of triaxial induction measurements performed with multiple transmitter-receiver configurations employs a parallel direct solver. The inversion uses a pre-conditioned gradient-based method whose accuracy is improved using the Wolfe conditions to estimate optimal step lengths at each iteration. The large transmitter-receiver offsets, used in the latest generation of commercial directional resistivity tools, improve the depth of investigation to over 30 m from the wellbore. Several challenging synthetic examples confirm the feasibility of the full 3-D inversion-based interpretations for these distances, hence enabling the integration of resistivity measurements with seismic amplitude data to improve the forecast of the petrophysical and fluid properties. Employing parallel direct solvers for the triaxial induction problems allows for large reductions in computational effort, thereby opening the possibility to invert multiposition 3-D data in practical CPU times.

  8. Total body neutron activation analysis of calcium: calibration and normalisation

    Energy Technology Data Exchange (ETDEWEB)

    Kennedy, N S.J.; Eastell, R; Ferrington, C M; Simpson, J D; Strong, J A [Western General Hospital, Edinburgh (UK); Smith, M A; Tothill, P [Royal Infirmary, Edinburgh (UK)

    1982-05-01

    An irradiation system has been designed, using a neutron beam from a cyclotron, which optimises the uniformity of activation of calcium. Induced activity is measured in a scanning, shadow-shield whole-body counter. Calibration has been effected and reproducibility assessed with three different types of phantom. Corrections were derived for variations in body height, depth and fat thickness. The coefficient of variation for repeated measurements of an anthropomorphic phantom was 1.8% for an absorbed dose equivalent of 13 mSv (1.3 rem). Measurements of total body calcium in 40 normal adults were used to derive normalisation factors which predict the normal calcium in a subject of given size and age. The coefficient of variation of normalised calcium was 6.2% in men and 6.6% in women, with the demonstration of an annual loss of 1.5% after the menopause. The narrow range should make single measurements useful for diagnostic purposes.

  9. Guidelines for normalising Early Modern English corpora: Decisions and justifications

    Directory of Open Access Journals (Sweden)

    Archer Dawn

    2015-03-01

    Full Text Available Corpora of Early Modern English have been collected and released for research for a number of years. With large scale digitisation activities gathering pace in the last decade, much more historical textual data is now available for research on numerous topics including historical linguistics and conceptual history. We summarise previous research which has shown that it is necessary to map historical spelling variants to modern equivalents in order to successfully apply natural language processing and corpus linguistics methods. Manual and semiautomatic methods have been devised to support this normalisation and standardisation process. We argue that it is important to develop a linguistically meaningful rationale to achieve good results from this process. In order to do so, we propose a number of guidelines for normalising corpora and show how these guidelines have been applied in the Corpus of English Dialogues.

  10. The practical use of resistance modelling to interpret the gas separation properties of hollow fiber membranes

    International Nuclear Information System (INIS)

    Ahmad Fauzi Ismail; Shilton, S.J.

    2000-01-01

    A simple resistance modelling methodology is presented for gas transport through asymmetric polymeric membranes. The methodology allows fine structural properties such as active layer thickness and surface porosity, to be determined from experimental gas permeation data. This paper, which could be regarded as a practical guide, shows that resistance modeling, if accompanied by realistic working assumptions, need not be difficult and can provide a valuable insight into the relationships between the membrane fabrication conditions and performance of gas separation membranes. (Author)

  11. Integrated interpretation of seismic and resistivity images across the «Val d'Agri» graben (Italy

    Directory of Open Access Journals (Sweden)

    E. Ceragioli

    2002-06-01

    Full Text Available Val d'Agri is a «recent SSW - NNE graben» located in the middle of the Southern Apennines thrust belt «chain» and emplaced in Plio-Pleistocene.The recent sedimentation of the valley represents a local critical geophysical problem. Several strong near surface velocity anomalies and scattering degrades seismic data in different ways and compromises the seismic visibility. In 1998, ENI and Enterprise, with the contribution of the European Community (ESIT R & D project - Enhance Seismic In Thrust Belt; EU Thermie fund acquired two «experimental seismic and Resistivity lines» across the valley. The purpose of the project was to look for methods able to enhance seismic data quality and optimize the data processing flow for «thrust belt» areas. During the work, it was clear that some part of the seismic data processing flow could be used for the detailed geological interpretation of the near subsurface too. In fact, the integrated interpretation of the near surface tomography velocity/depth seismic section, built for enhancing the resolution of static corrections, with the HR resistivity profile, acquired for enhancing the seismic source coupling, allowed a quite detailed lithological interpretation of the main shallow velocity changes and the 2D reconstruction of the structural setting of the valley.

  12. ASGDB: a specialised genomic resource for interpreting Anopheles sinensis insecticide resistance.

    Science.gov (United States)

    Zhou, Dan; Xu, Yang; Zhang, Cheng; Hu, Meng-Xue; Huang, Yun; Sun, Yan; Ma, Lei; Shen, Bo; Zhu, Chang-Liang

    2018-01-10

    Anopheles sinensis is an important malaria vector in Southeast Asia. The widespread emergence of insecticide resistance in this mosquito species poses a serious threat to the efficacy of malaria control measures, particularly in China. Recently, the whole-genome sequencing and de novo assembly of An. sinensis (China strain) has been finished. A series of insecticide-resistant studies in An. sinensis have also been reported. There is a growing need to integrate these valuable data to provide a comprehensive database for further studies on insecticide-resistant management of An. sinensis. A bioinformatics database named An. sinensis genome database (ASGDB) was built. In addition to being a searchable database of published An. sinensis genome sequences and annotation, ASGDB provides in-depth analytical platforms for further understanding of the genomic and genetic data, including visualization of genomic data, orthologous relationship analysis, GO analysis, pathway analysis, expression analysis and resistance-related gene analysis. Moreover, ASGDB provides a panoramic view of insecticide resistance studies in An. sinensis in China. In total, 551 insecticide-resistant phenotypic and genotypic reports on An. sinensis distributed in Chinese malaria-endemic areas since the mid-1980s have been collected, manually edited in the same format and integrated into OpenLayers map-based interface, which allows the international community to assess and exploit the high volume of scattered data much easier. The database has been given the URL: http://www.asgdb.org /. ASGDB was built to help users mine data from the genome sequence of An. sinensis easily and effectively, especially with its advantages in insecticide resistance surveillance and control.

  13. Interpretation of 2D Resistivity with Engineering Characterisation of Subsurface Exploration in Nusajaya Johor, Malaysia

    Science.gov (United States)

    Akip Tan, S. N. Mohd; Dan, M. F. Md; Edy Tonnizam, M.; Saad, R.; Madun, A.; Hazreek, Z. A. M.

    2018-04-01

    2-D resistivity technique and pole-dipole array with spacing of 2 m electrode and total spacing of 80 m were adopted to map and characterize the shallow subsurface in a sedimentary area at Nusajaya, Johor. Geological field mapping and laboratory testing were conducted to determine weathering grades. Res2Dinv software was used to generate the inversion model resistivity. The result shows sandstone contains iron mineral (30-1000ohm-m) and weathered sandstone (500-1000 ohm-m). The lowest layer represents sandstone and siltstone with the highest range from 1500 through 5000 ohm-m. The weathering grade IV and V of sandstone in the actual profile indicates the range from 30 to 1000 ohm-m, whereas grade II and III in ground mass matched the higest range. Overall, the increase of weathering grade influenced both the physical properties and strength of rocks.

  14. Microstructural characterisation of a P91 steel normalised and tempered at different temperatures

    International Nuclear Information System (INIS)

    Hurtado-Norena, C.; Danon, C.A.; Luppo, M.I.; Bruzzoni, P.

    2015-01-01

    9%Cr-1%Mo martensitic-ferritic steels are used in power plant components with operating temperatures of around 600 deg. C because of their good mechanical properties at high temperature as well as good oxidation resistance. These steels are generally used in the normalised and tempered condition. This treatment results in a structure of tempered lath martensite where the precipitates are distributed along the lath interfaces and within the martensite laths. The characterisation of these precipitates is of fundamental importance because of their relationship with the creep behaviour of these steels in service. In the present work, the different types of precipitates found in these steels have been studied on specimens in different metallurgical conditions. The techniques used in this investigation were X-ray diffraction with synchrotron light, scanning electron microscopy, energy dispersive microanalysis and transmission electron microscopy. (authors)

  15. Utilization of Point Clouds Characteristics in Interpretation and Evaluation Geophysical Resistivity Surveying of Unstable Running Block

    Directory of Open Access Journals (Sweden)

    Marcel Brejcha

    2016-05-01

    Full Text Available Close to human residences the places often abound where anthropogenic activity and external factors cause their changes. The changes can often influence their inhabitants’ life thanks to incipient dangerous places. The project of successful design of measures to ensure stability of unstable running blocks depends on chosen approaches and primary resource preparation. Utilization of modern technologies in their taking and processing is required nowadays. The paper describes the taking and processing of data for project of solution „Stabilization of unstable running block“ in a municipal settled part with efficient utilization of unusual method of processing of geophysical resistivity method.

  16. Analysis and interpretation of the performance degradation of glass Resistive Plate Chambers operated in streamer mode

    CERN Document Server

    Calcaterra, A; Patteri, P; Piccolo, M; Della Mea, G; Restello, S; Ferri, F; Musella, P; Redaelli, N; Tabarelli de Fatis, T; Tinti, G; Mannocchi, G; Trinchero, G

    2007-01-01

    The long-term stability of Resistive Plate Chambers (RPCs) with glass electrodes was studied for one year with a dedicated test station hosting about 10 m2 of detectors. RPCs were operated in streamer mode with a ternary gas mixture containing argon (27%), isobutane (9%) and tetrafluoroethane (64%). Environmental conditions were kept under control and, in particular, the water pollution in the gas, deemed responsible for the degradation of glass RPC performance, was monitored never to exceed 30 ppm in the exhaust line. Evidence for a substantial aging of the detectors was observed, resulting in a loss of efficiency correlated to an increased rate of spurious streamers. This can be ascribed to the chemical attack of the glass surface by hydrofluoric acid formed in the streamer process, as confirmed by detailed morphological and chemical analyses of the electrode surface. Our results strengthen the indication that the instability of glass RPCs in the long term is related to the use of fluorocarbons as quenching...

  17. 1-D DC Resistivity Modeling and Interpretation in Anisotropic Media Using Particle Swarm Optimization

    Science.gov (United States)

    Pekşen, Ertan; Yas, Türker; Kıyak, Alper

    2014-09-01

    We examine the one-dimensional direct current method in anisotropic earth formation. We derive an analytic expression of a simple, two-layered anisotropic earth model. Further, we also consider a horizontally layered anisotropic earth response with respect to the digital filter method, which yields a quasi-analytic solution over anisotropic media. These analytic and quasi-analytic solutions are useful tests for numerical codes. A two-dimensional finite difference earth model in anisotropic media is presented in order to generate a synthetic data set for a simple one-dimensional earth. Further, we propose a particle swarm optimization method for estimating the model parameters of a layered anisotropic earth model such as horizontal and vertical resistivities, and thickness. The particle swarm optimization is a naturally inspired meta-heuristic algorithm. The proposed method finds model parameters quite successfully based on synthetic and field data. However, adding 5 % Gaussian noise to the synthetic data increases the ambiguity of the value of the model parameters. For this reason, the results should be controlled by a number of statistical tests. In this study, we use probability density function within 95 % confidence interval, parameter variation of each iteration and frequency distribution of the model parameters to reduce the ambiguity. The result is promising and the proposed method can be used for evaluating one-dimensional direct current data in anisotropic media.

  18. Microvillar cell surface as a natural defense system against xenobiotics: a new interpretation of multidrug resistance.

    Science.gov (United States)

    Lange, K; Gartzke, J

    2001-08-01

    The phenomenon of multidrug resistance (MDR) is reinterpreted on the basis of the recently proposed concept of microvillar signaling. According to this notion, substrate and ion fluxes across the surface of differentiated cells occur via transporters and ion channels that reside in membrane domains at the tips of microvilli (MV). The flux rates are regulated by the actin-based cytoskeletal core structure of MV, acting as a diffusion barrier between the microvillar tip compartment and the cytoplasm. The expression of this diffusion barrier system is a novel aspect of cell differentiation and represents a functional component of the natural defense system of epithelial cells against environmental hazardous ions and lipophilic compounds. Because of the specific organization of epithelial Ca(2+) signaling and the secretion, lipophilic compounds associated with the plasma membrane are transferred from the basal to the apical cell surface by a lipid flow mechanism. Drug release from the apical pole occurs by either direct secretion from the cell surface or metabolization by the microvillar cytochrome P-450 system and efflux of the metabolites and conjugation products through the large multifunctional anion channels localized in apical MV. The natural microvillar defense system also provides a mechanistic basis of acquired MDR in tumor cells. The microvillar surface organization is lost in rapidly growing cells such as tumor or embryonic cells but is restored during exposure of tumor cells to cytotoxins by induction of a prolonged G(0)/G(1) resting phase.

  19. Normalisation of body composition parameters for nutritional assessment

    International Nuclear Information System (INIS)

    Preston, Thomas

    2014-01-01

    Full text: Normalisation of body composition parameters to an index of body size facilitates comparison of a subject’s measurements with those of a population. There is an obvious focus on indexes of obesity, but first it is informative to consider Fat Free Mass (FFM) in the context of common anthropometric measures of body size namely, height and weight. The contention is that FFM is a more physiological measure of body size than body mass. Many studies have shown that FFM relates to height ^p. Although there is debate over the appropriate exponent especially in early life, it appears to lie between 2 and 3. If 2, then FFM Index (FFMI; kg/m2) and Fat Mass Index (FMI; kg/m2) can be summed to give BMI. If 3 were used as exponent, then FFMI (kg/m3) plus FMI (kg/m3) gives the Ponderal Index (PI; weight/height3). In 2013, Burton argued that that a cubic exponent is appropriate for normalisation as it is a dimensionless quotient. In 2012, Wang and co-workers repeated earlier observations showing a strong linear relationship between FFM and height3. The importance of the latter study comes from the fact that a 4 compartment body composition model was used, which is recognised as the most accurate means of describing FFM. Once the basis of a FFMI has been defined it can be used to compare measurements with those of a population, either directly, as a ratio to a norm or as a Z-score. FFMI charts could be developed for use in child growth. Other related indexes can be determined for use in specific circumstances such as: body cell mass index (growth and wasting); skeletal muscle mass index (SMMI) or appendicular SMMI (growth and sarcopenia); bone mineral mass index (osteoporosis); extracellular fluid index (hydration). Finally, it is logical that the same system is used to define an adiposity index, so Fat Mass Index (FMI; kg/height3) can be used as it is consistent with FFMI (kg/height3) and PI. It should also be noted that the index FM/FFM, describes an individual

  20. Inference of financial networks using the normalised mutual information rate

    Science.gov (United States)

    2018-01-01

    In this paper, we study data from financial markets, using the normalised Mutual Information Rate. We show how to use it to infer the underlying network structure of interrelations in the foreign currency exchange rates and stock indices of 15 currency areas. We first present the mathematical method and discuss its computational aspects, and apply it to artificial data from chaotic dynamics and to correlated normal-variates data. We then apply the method to infer the structure of the financial system from the time-series of currency exchange rates and stock indices. In particular, we study and reveal the interrelations among the various foreign currency exchange rates and stock indices in two separate networks, of which we also study their structural properties. Our results show that both inferred networks are small-world networks, sharing similar properties and having differences in terms of assortativity. Importantly, our work shows that global economies tend to connect with other economies world-wide, rather than creating small groups of local economies. Finally, the consistent interrelations depicted among the 15 currency areas are further supported by a discussion from the viewpoint of economics. PMID:29420644

  1. Inference of financial networks using the normalised mutual information rate.

    Science.gov (United States)

    Goh, Yong Kheng; Hasim, Haslifah M; Antonopoulos, Chris G

    2018-01-01

    In this paper, we study data from financial markets, using the normalised Mutual Information Rate. We show how to use it to infer the underlying network structure of interrelations in the foreign currency exchange rates and stock indices of 15 currency areas. We first present the mathematical method and discuss its computational aspects, and apply it to artificial data from chaotic dynamics and to correlated normal-variates data. We then apply the method to infer the structure of the financial system from the time-series of currency exchange rates and stock indices. In particular, we study and reveal the interrelations among the various foreign currency exchange rates and stock indices in two separate networks, of which we also study their structural properties. Our results show that both inferred networks are small-world networks, sharing similar properties and having differences in terms of assortativity. Importantly, our work shows that global economies tend to connect with other economies world-wide, rather than creating small groups of local economies. Finally, the consistent interrelations depicted among the 15 currency areas are further supported by a discussion from the viewpoint of economics.

  2. Normalisation in product life cycle assessment: an LCA of the global and European economic systems in the year 2000.

    Science.gov (United States)

    Sleeswijk, Anneke Wegener; van Oers, Lauran F C M; Guinée, Jeroen B; Struijs, Jaap; Huijbregts, Mark A J

    2008-02-01

    In the methodological context of the interpretation of environmental life cycle assessment (LCA) results, a normalisation study was performed. 15 impact categories were accounted for, including climate change, acidification, eutrophication, human toxicity, ecotoxicity, depletion of fossil energy resources, and land use. The year 2000 was chosen as a reference year, and information was gathered on two spatial levels: the global and the European level. From the 860 environmental interventions collected, 48 interventions turned out to account for at least 75% of the impact scores of all impact categories. All non-toxicity related, emission dependent impacts are fully dominated by the bulk emissions of only 10 substances or substance groups: CO(2), CH(4), SO(2), NO(x), NH(3), PM(10), NMVOC, and (H)CFCs emissions to air and emissions of N- and P-compounds to fresh water. For the toxicity-related emissions (pesticides, organics, metal compounds and some specific inorganics), the availability of information was still very limited, leading to large uncertainty in the corresponding normalisation factors. Apart from their usefulness as a reference for LCA studies, the results of this study stress the importance of efficient measures to combat bulk emissions and to promote the registration of potentially toxic emissions on a more comprehensive scale.

  3. Introducing carrying capacity-based normalisation in LCA: framework and development of references at midpoint level

    DEFF Research Database (Denmark)

    Bjørn, Anders; Hauschild, Michael Zwicky

    2015-01-01

    carrying capacity-based normalisation references. The purpose of this article is to present a framework for normalisation against carrying capacity-based references and to develop average normalisation references (NR) for Europe and the world for all those midpoint impact categories commonly included....... A literature review was carried out to identify scientifically sound thresholds for each impact category. Carrying capacities were then calculated from these thresholds and expressed in metrics identical to midpoint indicators giving priority to those recommended by ILCD. NR was expressed as the carrying...... ozone formation and soil quality were found to exceed carrying capacities several times.The developed carrying capacity-based normalisation references offer relevant supplementary reference information to the currently applied references based on society’s background interventions by supporting...

  4. Interpreting Low Personality Psychopathology--Five Aggressiveness Scores on the MMPI-2: Graphical, Robust, and Resistant Data Analysis

    Science.gov (United States)

    Weisenburger, Susan M.; Harkness, Allan R.; McNulty, John L.; Graham, John R.; Ben-Porath, Yossef S.

    2008-01-01

    The Minnesota Mutiphasic Personality Inventory-2 (MMPI-2)-based Personality Psychopathology-Five (PSY-5) scales provide an overview of personality individual differences. Several textbooks and a test report offer instruction on interpreting MMPI-2 PSY-5 scores. On the basis of an earlier item response theory article (S. V. Rouse, M. S. Finger,…

  5. Normalisation of spot urine samples to 24-h collection for assessment of exposure to uranium

    International Nuclear Information System (INIS)

    Marco, R.; Katorza, E.; Gonen, R.; German, U.; Tshuva, A.; Pelled, O.; Paz-tal, O.; Adout, A.; Karpas, Z.

    2008-01-01

    For dose assessment of workers at Nuclear Research Center Negev exposed to natural uranium, spot urine samples are analysed and the results are normalised to 24-h urine excretion based on 'standard' man urine volume of 1.6 l d -1 . In the present work, the urine volume, uranium level and creatinine concentration were determined in two or three 24-h urine collections from 133 male workers (319 samples) and 33 female workers (88 samples). Three volunteers provided urine spot samples from each voiding during a 24-h period and a good correlation was found between the relative level of creatinine and uranium in spot samples collected from the same individual. The results show that normalisation of uranium concentration to creatinine in a spot sample represents the 24-h content of uranium better than normalisation to the standard volume and may be used to reduce the uncertainty of dose assessment based on spot samples. (authors)

  6. A novel approach to signal normalisation in atmospheric pressure ionisation mass spectrometry.

    Science.gov (United States)

    Vogeser, Michael; Kirchhoff, Fabian; Geyer, Roland

    2012-07-01

    The aim of our study was to test an alternative principle of signal normalisation in LC-MS/MS. During analyses, post column infusion of the target analyte is done via a T-piece, generating an "area under the analyte peak" (AUP). The ratio of peak area to AUP is assessed as assay response. Acceptable analytical performance of this principle was found for an exemplary analyte. Post-column infusion may allow normalisation of ion suppression not requiring any additional standard compound. This approach can be useful in situations where no appropriate compound is available for classical internal standardisation. Copyright © 2012 Elsevier B.V. All rights reserved.

  7. A normalisation for the four - detector system for gamma - gamma angular correlation studies

    International Nuclear Information System (INIS)

    Kiang, G.C.; Chen, C.H.; Niu, W.F.

    1994-01-01

    A normalisation method for the multiple - HPGe - detector system is described. The system consists of four coaxial HPGe detectors with a CAMAC event - by - event data acquisition system, enabling to measure six gamma -gamma coincidences of angles simultaneously. An application for gamma - gamma correlation studies of Kr 82 is presented and discussed. 3 figs., 6 refs. (author)

  8. Normalisation of the peaceful use of nuclear energy - consequences for its legal regulation

    International Nuclear Information System (INIS)

    Birkhofer, A.; Lukes, R.

    1985-01-01

    The five reports in this book deal with the importance of the peaceful use of nuclear energy, as well as with several aspects of normalisation. The spectrum of the reports underlines the benefit for the support of the peaceful use of nuclear energy. (WG) [de

  9. Normalised quantitative polymerase chain reaction for diagnosis of tuberculosis-associated uveitis.

    Science.gov (United States)

    Barik, Manas Ranjan; Rath, Soveeta; Modi, Rohit; Rana, Rajkishori; Reddy, Mamatha M; Basu, Soumyava

    2018-05-01

    Polymerase chain reaction (PCR)-based diagnosis of tuberculosis-associated uveitis (TBU) in TB-endemic countries is challenging due to likelihood of latent mycobacterial infection in both immune and non-immune cells. In this study, we investigated normalised quantitative PCR (nqPCR) in ocular fluids (aqueous/vitreous) for diagnosis of TBU in a TB-endemic population. Mycobacterial copy numbers (mpb64 gene) were normalised to host genome copy numbers (RNAse P RNA component H1 [RPPH1] gene) in TBU (n = 16) and control (n = 13) samples (discovery cohort). The mpb64:RPPH1 ratios (normalised value) from each TBU and control sample were tested against the current reference standard i.e. clinically-diagnosed TBU, to generate Receiver Operating Characteristic (ROC) curves. The optimum cut-off value of mpb64:RPPH1 ratio (0.011) for diagnosing TBU was identified from the highest Youden index. This cut-off value was then tested in a different cohort of TBU and controls (validation cohort, 20 cases and 18 controls), where it yielded specificity, sensitivity and diagnostic accuracy of 94.4%, 85.0%, and 89.4% respectively. The above values for conventional quantitative PCR (≥1 copy of mpb64 per reaction) were 61.1%, 90.0%, and 74.3% respectively. Normalisation markedly improved the specificity and diagnostic accuracy of quantitative PCR for diagnosis of TBU. Copyright © 2018 Elsevier Ltd. All rights reserved.

  10. Relationships between the normalised difference vegetation index and temperature fluctuations in post-mining sites

    Czech Academy of Sciences Publication Activity Database

    Bujalský, L.; Jirka, V.; Zemek, František; Frouz, J.

    2018-01-01

    Roč. 32, č. 4 (2018), s. 254-263 ISSN 1748-0930 R&D Projects: GA MŠk(CZ) LO1415 Institutional support: RVO:67179843 Keywords : temperature * normalised difference * vegetation index (NDVI) * vegetation cover * remote sensing Subject RIV: DF - Soil Science Impact factor: 1.078, year: 2016

  11. An efficient Markov chain Monte Carlo method for distributions with intractable normalising constants

    DEFF Research Database (Denmark)

    Møller, Jesper; Pettitt, A. N.; Reeves, R.

    2006-01-01

    Maximum likelihood parameter estimation and sampling from Bayesian posterior distributions are problematic when the probability density for the parameter of interest involves an intractable normalising constant which is also a function of that parameter. In this paper, an auxiliary variable metho...

  12. Normalisation et certification dans le photovoltaïque: perspectives juridiques.

    OpenAIRE

    Boy , Laurence

    2012-01-01

    International audience; Legal approach of standardization in photovoltaic industry in France. Legal sources. Stakeholder"s liabillities. Competition aspects.; Approche juridique de la normalisation et de la certification dans le domaine du photovoltaïque en France. Sources du droit. Responsabilités des acteurs.Aspects concurrentiels.

  13. Bounded real and positive real balanced truncation using Σ-normalised coprime factors

    NARCIS (Netherlands)

    Trentelman, H.L.

    2009-01-01

    In this article, we will extend the method of balanced truncation using normalised right coprime factors of the system transfer matrix to balanced truncation with preservation of half line dissipativity. Special cases are preservation of positive realness and bounded realness. We consider a half

  14. CCTV Surveillance in Primary Schools: Normalisation, Resistance, and Children's Privacy Consciousness

    Science.gov (United States)

    Birnhack, Michael; Perry-Hazan, Lotem; German Ben-Hayun, Shiran

    2018-01-01

    This study explored how primary school children perceive school surveillance by Closed Circuit TV systems (CCTVs) and how their perceptions relate to their privacy consciousness. It drew on interviews with 57 children, aged 9-12, who were enrolled in three Israeli public schools that had installed CCTVs, and on information gathered from members of…

  15. Normalisation genes for expression analyses in the brown alga model Ectocarpus siliculosus

    Directory of Open Access Journals (Sweden)

    Rousvoal Sylvie

    2008-08-01

    Full Text Available Abstract Background Brown algae are plant multi-cellular organisms occupying most of the world coasts and are essential actors in the constitution of ecological niches at the shoreline. Ectocarpus siliculosus is an emerging model for brown algal research. Its genome has been sequenced, and several tools are being developed to perform analyses at different levels of cell organization, including transcriptomic expression analyses. Several topics, including physiological responses to osmotic stress and to exposure to contaminants and solvents are being studied in order to better understand the adaptive capacity of brown algae to pollution and environmental changes. A series of genes that can be used to normalise expression analyses is required for these studies. Results We monitored the expression of 13 genes under 21 different culture conditions. These included genes encoding proteins and factors involved in protein translation (ribosomal protein 26S, EF1alpha, IF2A, IF4E and protein degradation (ubiquitin, ubiquitin conjugating enzyme or folding (cyclophilin, and proteins involved in both the structure of the cytoskeleton (tubulin alpha, actin, actin-related proteins and its trafficking function (dynein, as well as a protein implicated in carbon metabolism (glucose 6-phosphate dehydrogenase. The stability of their expression level was assessed using the Ct range, and by applying both the geNorm and the Normfinder principles of calculation. Conclusion Comparisons of the data obtained with the three methods of calculation indicated that EF1alpha (EF1a was the best reference gene for normalisation. The normalisation factor should be calculated with at least two genes, alpha tubulin, ubiquitin-conjugating enzyme or actin-related proteins being good partners of EF1a. Our results exclude actin as a good normalisation gene, and, in this, are in agreement with previous studies in other organisms.

  16. REPORTING SOCIETAL : LIMITES ET ENJEUX DE LA PROPOSITION DE NORMALISATION INTERNATIONALE " GLOBAL REPORTING INITIATIVE "

    OpenAIRE

    Michel Capron; Françoise Quairel

    2003-01-01

    International audience; En s'inspirant de la normalisation comptable anglo-saxonne, la Global Reporting Initiative (GRI) propose un référentiel de publication volontaire d'informations sociétales. La transposition présente des limites qui rendent en fait ses principes inapplicables. Néanmoins il tend à s'imposer et les grandes entreprises peuvent y trouver le moyen d'éviter une régulation contraignante.

  17. Use and misuse of temperature normalisation in meta-analyses of thermal responses of biological traits

    Directory of Open Access Journals (Sweden)

    Dimitrios - Georgios Kontopoulos

    2018-02-01

    Full Text Available There is currently unprecedented interest in quantifying variation in thermal physiology among organisms, especially in order to understand and predict the biological impacts of climate change. A key parameter in this quantification of thermal physiology is the performance or value of a rate, across individuals or species, at a common temperature (temperature normalisation. An increasingly popular model for fitting thermal performance curves to data—the Sharpe-Schoolfield equation—can yield strongly inflated estimates of temperature-normalised rate values. These deviations occur whenever a key thermodynamic assumption of the model is violated, i.e., when the enzyme governing the performance of the rate is not fully functional at the chosen reference temperature. Using data on 1,758 thermal performance curves across a wide range of species, we identify the conditions that exacerbate this inflation. We then demonstrate that these biases can compromise tests to detect metabolic cold adaptation, which requires comparison of fitness or rate performance of different species or genotypes at some fixed low temperature. Finally, we suggest alternative methods for obtaining unbiased estimates of temperature-normalised rate values for meta-analyses of thermal performance across species in climate change impact studies.

  18. Normalisation process theory: a framework for developing, evaluating and implementing complex interventions

    LENUS (Irish Health Repository)

    Murray, Elizabeth

    2010-10-20

    Abstract Background The past decade has seen considerable interest in the development and evaluation of complex interventions to improve health. Such interventions can only have a significant impact on health and health care if they are shown to be effective when tested, are capable of being widely implemented and can be normalised into routine practice. To date, there is still a problematic gap between research and implementation. The Normalisation Process Theory (NPT) addresses the factors needed for successful implementation and integration of interventions into routine work (normalisation). Discussion In this paper, we suggest that the NPT can act as a sensitising tool, enabling researchers to think through issues of implementation while designing a complex intervention and its evaluation. The need to ensure trial procedures that are feasible and compatible with clinical practice is not limited to trials of complex interventions, and NPT may improve trial design by highlighting potential problems with recruitment or data collection, as well as ensuring the intervention has good implementation potential. Summary The NPT is a new theory which offers trialists a consistent framework that can be used to describe, assess and enhance implementation potential. We encourage trialists to consider using it in their next trial.

  19. Oral benfotiamine plus alpha-lipoic acid normalises complication-causing pathways in type 1 diabetes.

    Science.gov (United States)

    Du, X; Edelstein, D; Brownlee, M

    2008-10-01

    We determined whether fixed doses of benfotiamine in combination with slow-release alpha-lipoic acid normalise markers of reactive oxygen species-induced pathways of complications in humans. Male participants with and without type 1 diabetes were studied in the General Clinical Research Centre of the Albert Einstein College of Medicine. Glycaemic status was assessed by measuring baseline values of three different indicators of hyperglycaemia. Intracellular AGE formation, hexosamine pathway activity and prostacyclin synthase activity were measured initially, and after 2 and 4 weeks of treatment. In the nine participants with type 1 diabetes, treatment had no effect on any of the three indicators used to assess hyperglycaemia. However, treatment with benfotiamine plus alpha-lipoic acid completely normalised increased AGE formation, reduced increased monocyte hexosamine-modified proteins by 40% and normalised the 70% decrease in prostacyclin synthase activity from 1,709 +/- 586 pg/ml 6-keto-prostaglandin F(1alpha) to 4,696 +/- 533 pg/ml. These results show that the previously demonstrated beneficial effects of these agents on complication-causing pathways in rodent models of diabetic complications also occur in humans with type 1 diabetes.

  20. Normalisation process theory: a framework for developing, evaluating and implementing complex interventions

    Directory of Open Access Journals (Sweden)

    Ong Bie

    2010-10-01

    Full Text Available Abstract Background The past decade has seen considerable interest in the development and evaluation of complex interventions to improve health. Such interventions can only have a significant impact on health and health care if they are shown to be effective when tested, are capable of being widely implemented and can be normalised into routine practice. To date, there is still a problematic gap between research and implementation. The Normalisation Process Theory (NPT addresses the factors needed for successful implementation and integration of interventions into routine work (normalisation. Discussion In this paper, we suggest that the NPT can act as a sensitising tool, enabling researchers to think through issues of implementation while designing a complex intervention and its evaluation. The need to ensure trial procedures that are feasible and compatible with clinical practice is not limited to trials of complex interventions, and NPT may improve trial design by highlighting potential problems with recruitment or data collection, as well as ensuring the intervention has good implementation potential. Summary The NPT is a new theory which offers trialists a consistent framework that can be used to describe, assess and enhance implementation potential. We encourage trialists to consider using it in their next trial.

  1. A comparison of parametric and nonparametric methods for normalising cDNA microarray data.

    Science.gov (United States)

    Khondoker, Mizanur R; Glasbey, Chris A; Worton, Bruce J

    2007-12-01

    Normalisation is an essential first step in the analysis of most cDNA microarray data, to correct for effects arising from imperfections in the technology. Loess smoothing is commonly used to correct for trends in log-ratio data. However, parametric models, such as the additive plus multiplicative variance model, have been preferred for scale normalisation, though the variance structure of microarray data may be of a more complex nature than can be accommodated by a parametric model. We propose a new nonparametric approach that incorporates location and scale normalisation simultaneously using a Generalised Additive Model for Location, Scale and Shape (GAMLSS, Rigby and Stasinopoulos, 2005, Applied Statistics, 54, 507-554). We compare its performance in inferring differential expression with Huber et al.'s (2002, Bioinformatics, 18, 96-104) arsinh variance stabilising transformation (AVST) using real and simulated data. We show GAMLSS to be as powerful as AVST when the parametric model is correct, and more powerful when the model is wrong. (c) 2007 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

  2. Reference gene identification for reliable normalisation of quantitative RT-PCR data in Setaria viridis.

    Science.gov (United States)

    Nguyen, Duc Quan; Eamens, Andrew L; Grof, Christopher P L

    2018-01-01

    Quantitative real-time polymerase chain reaction (RT-qPCR) is the key platform for the quantitative analysis of gene expression in a wide range of experimental systems and conditions. However, the accuracy and reproducibility of gene expression quantification via RT-qPCR is entirely dependent on the identification of reliable reference genes for data normalisation. Green foxtail ( Setaria viridis ) has recently been proposed as a potential experimental model for the study of C 4 photosynthesis and is closely related to many economically important crop species of the Panicoideae subfamily of grasses, including Zea mays (maize), Sorghum bicolor (sorghum) and Sacchurum officinarum (sugarcane). Setaria viridis (Accession 10) possesses a number of key traits as an experimental model, namely; (i) a small sized, sequenced and well annotated genome; (ii) short stature and generation time; (iii) prolific seed production, and; (iv) is amendable to Agrobacterium tumefaciens -mediated transformation. There is currently however, a lack of reference gene expression information for Setaria viridis ( S. viridis ). We therefore aimed to identify a cohort of suitable S. viridis reference genes for accurate and reliable normalisation of S. viridis RT-qPCR expression data. Eleven putative candidate reference genes were identified and examined across thirteen different S. viridis tissues. Of these, the geNorm and NormFinder analysis software identified SERINE / THERONINE - PROTEIN PHOSPHATASE 2A ( PP2A ), 5 '- ADENYLYLSULFATE REDUCTASE 6 ( ASPR6 ) and DUAL SPECIFICITY PHOSPHATASE ( DUSP ) as the most suitable combination of reference genes for the accurate and reliable normalisation of S. viridis RT-qPCR expression data. To demonstrate the suitability of the three selected reference genes, PP2A , ASPR6 and DUSP , were used to normalise the expression of CINNAMYL ALCOHOL DEHYDROGENASE ( CAD ) genes across the same tissues. This approach readily demonstrated the suitably of the three

  3. Can linear regression modeling help clinicians in the interpretation of genotypic resistance data? An application to derive a lopinavir-score.

    Science.gov (United States)

    Cozzi-Lepri, Alessandro; Prosperi, Mattia C F; Kjær, Jesper; Dunn, David; Paredes, Roger; Sabin, Caroline A; Lundgren, Jens D; Phillips, Andrew N; Pillay, Deenan

    2011-01-01

    The question of whether a score for a specific antiretroviral (e.g. lopinavir/r in this analysis) that improves prediction of viral load response given by existing expert-based interpretation systems (IS) could be derived from analyzing the correlation between genotypic data and virological response using statistical methods remains largely unanswered. We used the data of the patients from the UK Collaborative HIV Cohort (UK CHIC) Study for whom genotypic data were stored in the UK HIV Drug Resistance Database (UK HDRD) to construct a training/validation dataset of treatment change episodes (TCE). We used the average square error (ASE) on a 10-fold cross-validation and on a test dataset (the EuroSIDA TCE database) to compare the performance of a newly derived lopinavir/r score with that of the 3 most widely used expert-based interpretation rules (ANRS, HIVDB and Rega). Our analysis identified mutations V82A, I54V, K20I and I62V, which were associated with reduced viral response and mutations I15V and V91S which determined lopinavir/r hypersensitivity. All models performed equally well (ASE on test ranging between 1.1 and 1.3, p = 0.34). We fully explored the potential of linear regression to construct a simple predictive model for lopinavir/r-based TCE. Although, the performance of our proposed score was similar to that of already existing IS, previously unrecognized lopinavir/r-associated mutations were identified. The analysis illustrates an approach of validation of expert-based IS that could be used in the future for other antiretrovirals and in other settings outside HIV research.

  4. Interpretation of resistivity of Nd1.85Ce0.15CuO4-y using the electron-phonon spectral function determined from tunneling data

    International Nuclear Information System (INIS)

    Tralshawala, N.; Zasadzinski, J.F.; Coffey, L.; Huang, Q.

    1991-01-01

    Tunneling measurements of α 2 F(ω) of Nd 1.85 Ce 0.15 CuO 4-y are shown to be in good agreement with recent published results of the phonon density of states F(ω) from neutron scattering. The locations of peaks and valleys in both functions are similar, but the spectral weights differ, suggesting that α 2 has a strong energy dependence. We have used α 2 F(ω) to estimate the phonon contribution, ρ phonon (T), to published data of the temperature-dependent resistivity, ρ(T), for thin films and single crystals of Nd 1.85 Ce 0.15 CuO 4-y . When the phonon contribution is subtracted from the experimental data, a clear T 2 contribution remains over most of the temperature range. The T 2 contribution is interpreted to be due to three-dimensional electron-electron scattering, ρ e-e . There is also a correlation between the magnitude of ρ e-e , and the value of the plasma frequency, ω p [obtained from the determination of ρ phonon (T)], with a scaling which approximates ω p -10/3 . Such a scaling is expected from the carrier-concentration dependence of electron-electron scattering

  5. Interpretative commenting.

    Science.gov (United States)

    Vasikaran, Samuel

    2008-08-01

    * Clinical laboratories should be able to offer interpretation of the results they produce. * At a minimum, contact details for interpretative advice should be available on laboratory reports.Interpretative comments may be verbal or written and printed. * Printed comments on reports should be offered judiciously, only where they would add value; no comment preferred to inappropriate or dangerous comment. * Interpretation should be based on locally agreed or nationally recognised clinical guidelines where available. * Standard tied comments ("canned" comments) can have some limited use.Individualised narrative comments may be particularly useful in the case of tests that are new, complex or unfamiliar to the requesting clinicians and where clinical details are available. * Interpretative commenting should only be provided by appropriately trained and credentialed personnel. * Audit of comments and continued professional development of personnel providing them are important for quality assurance.

  6. Objective interpretation as conforming interpretation

    Directory of Open Access Journals (Sweden)

    Lidka Rodak

    2011-12-01

    Full Text Available The practical discourse willingly uses the formula of “objective interpretation”, with no regards to its controversial nature that has been discussed in literature.The main aim of the article is to investigate what “objective interpretation” could mean and how it could be understood in the practical discourse, focusing on the understanding offered by judicature.The thesis of the article is that objective interpretation, as identified with textualists’ position, is not possible to uphold, and should be rather linked with conforming interpretation. And what this actually implies is that it is not the virtue of certainty and predictability – which are usually associated with objectivity- but coherence that makes the foundation of applicability of objectivity in law.What could be observed from the analyses, is that both the phenomenon of conforming interpretation and objective interpretation play the role of arguments in the interpretive discourse, arguments that provide justification that interpretation is not arbitrary or subjective. With regards to the important part of the ideology of legal application which is the conviction that decisions should be taken on the basis of law in order to exclude arbitrariness, objective interpretation could be read as a question “what kind of authority “supports” certain interpretation”? that is almost never free of judicial creativity and judicial activism.One can say that, objective and conforming interpretation are just another arguments used in legal discourse.

  7. Normalised subband adaptive filtering with extended adaptiveness on degree of subband filters

    Science.gov (United States)

    Samuyelu, Bommu; Rajesh Kumar, Pullakura

    2017-12-01

    This paper proposes an adaptive normalised subband adaptive filtering (NSAF) to accomplish the betterment of NSAF performance. In the proposed NSAF, an extended adaptiveness is introduced from its variants in two ways. In the first way, the step-size is set adaptive, and in the second way, the selection of subbands is set adaptive. Hence, the proposed NSAF is termed here as variable step-size-based NSAF with selected subbands (VS-SNSAF). Experimental investigations are carried out to demonstrate the performance (in terms of convergence) of the VS-SNSAF against the conventional NSAF and its state-of-the-art adaptive variants. The results report the superior performance of VS-SNSAF over the traditional NSAF and its variants. It is also proved for its stability, robustness against noise and substantial computing complexity.

  8. Living under the influence: normalisation of alcohol consumption in our cities

    Directory of Open Access Journals (Sweden)

    Xisca Sureda

    2017-01-01

    Full Text Available Harmful use of alcohol is one of the world's leading health risks. A positive association between certain characteristics of the urban environment and individual alcohol consumption has been documented in previous research. When developing a tool characterising the urban environment of alcohol in the cities of Barcelona and Madrid we observed that alcohol is ever present in our cities. Urban residents are constantly exposed to a wide variety of alcohol products, marketing and promotion and signs of alcohol consumption. In this field note, we reflect the normalisation of alcohol in urban environments. We highlight the need for further research to better understand attitudes and practices in relation to alcohol consumption. This type of urban studies is necessary to support policy interventions to prevent and control harmful alcohol use.

  9. The normalisation of terror: the response of Israel's stock market to long periods of terrorism.

    Science.gov (United States)

    Peleg, Kobi; Regens, James L; Gunter, James T; Jaffe, Dena H

    2011-01-01

    Man-made disasters such as acts of terrorism may affect a society's resiliency and sensitivity to prolonged physical and psychological stress. The Israeli Tel Aviv stock market TA-100 Index was used as an indicator of reactivity to suicide terror bombings. After accounting for factors such as world market changes and attack severity and intensity, the analysis reveals that although Israel's financial base remained sensitive to each act of terror across the entire period of the Second Intifada (2000-06), sustained psychological resilience was indicated with no apparent overall market shift. In other words, we saw a 'normalisation of terror' following an extended period of continued suicide bombings. The results suggest that investors responded to less transitory global market forces, indicating sustained resilience and long-term market confidence. Future studies directly measuring investor expectations and reactions to man-made disasters, such as terrorism, are warranted. © 2011 The Author(s). Disasters © Overseas Development Institute, 2011.

  10. Living under the influence: normalisation of alcohol consumption in our cities.

    Science.gov (United States)

    Sureda, Xisca; Villalbí, Joan R; Espelt, Albert; Franco, Manuel

    Harmful use of alcohol is one of the world's leading health risks. A positive association between certain characteristics of the urban environment and individual alcohol consumption has been documented in previous research. When developing a tool characterising the urban environment of alcohol in the cities of Barcelona and Madrid we observed that alcohol is ever present in our cities. Urban residents are constantly exposed to a wide variety of alcohol products, marketing and promotion and signs of alcohol consumption. In this field note, we reflect the normalisation of alcohol in urban environments. We highlight the need for further research to better understand attitudes and practices in relation to alcohol consumption. This type of urban studies is necessary to support policy interventions to prevent and control harmful alcohol use. Copyright © 2016 SESPAS. Publicado por Elsevier España, S.L.U. All rights reserved.

  11. Penultimate interpretation.

    Science.gov (United States)

    Neuman, Yair

    2010-10-01

    Interpretation is at the center of psychoanalytic activity. However, interpretation is always challenged by that which is beyond our grasp, the 'dark matter' of our mind, what Bion describes as ' O'. O is one of the most central and difficult concepts in Bion's thought. In this paper, I explain the enigmatic nature of O as a high-dimensional mental space and point to the price one should pay for substituting the pre-symbolic lexicon of the emotion-laden and high-dimensional unconscious for a low-dimensional symbolic representation. This price is reification--objectifying lived experience and draining it of vitality and complexity. In order to address the difficulty of approaching O through symbolization, I introduce the term 'Penultimate Interpretation'--a form of interpretation that seeks 'loopholes' through which the analyst and the analysand may reciprocally save themselves from the curse of reification. Three guidelines for 'Penultimate Interpretation' are proposed and illustrated through an imaginary dialogue. Copyright © 2010 Institute of Psychoanalysis.

  12. Évolution de la normalisation dans le domaine des oléagineux et des corps gras

    Directory of Open Access Journals (Sweden)

    Quinsac Alain

    2003-07-01

    Full Text Available La normalisation joue un grand rôle dans les échanges économiques en participant à l’ouverture et à la transparence des marchés. La filière des Oléagineux et des Corps Gras a intégré depuis longtemps la normalisation dans sa stratégie. Élaborés à partir des besoins de la profession et notamment au niveau de la relation client-fournisseur, les programmes ont concerné principalement l’échantillonnage et l’analyse. Depuis quelques années, une forte évolution du contexte socio-économique et réglementaire (utilisation non-alimentaire, sécurité alimentaire, assurance qualité, a élargi le champ de la normalisation. La démarche normative adoptée dans le cas des bio-diesels et de la détection des OGM dans les oléagineux est expliquée. Les conséquences de l’évolution de la normalisation et les enjeux pour la profession des oléagineux dans le futur sont évoqués.

  13. ENEKuS--A Key Model for Managing the Transformation of the Normalisation of the Basque Language in the Workplace

    Science.gov (United States)

    Marko, Inazio; Pikabea, Inaki

    2013-01-01

    The aim of this study is to develop a reference model for intervention in the language processes applied to the transformation of language normalisation within organisations of a socio-economic nature. It is based on a case study of an experiment carried out over 10 years within a trade union confederation, and has pursued a strategy of a…

  14. Interpreting Physics

    CERN Document Server

    MacKinnon, Edward

    2012-01-01

    This book is the first to offer a systematic account of the role of language in the development and interpretation of physics. An historical-conceptual analysis of the co-evolution of mathematical and physical concepts leads to the classical/quatum interface. Bohrian orthodoxy stresses the indispensability of classical concepts and the functional role of mathematics. This book analyses ways of extending, and then going beyond this orthodoxy orthodoxy. Finally, the book analyzes how a revised interpretation of physics impacts on basic philosophical issues: conceptual revolutions, realism, and r

  15. Performing Interpretation

    Science.gov (United States)

    Kothe, Elsa Lenz; Berard, Marie-France

    2013-01-01

    Utilizing a/r/tographic methodology to interrogate interpretive acts in museums, multiple areas of inquiry are raised in this paper, including: which knowledge is assigned the greatest value when preparing a gallery talk; what lies outside of disciplinary knowledge; how invitations to participate invite and disinvite in the same gesture; and what…

  16. Implementation of the SMART MOVE intervention in primary care: a qualitative study using normalisation process theory.

    Science.gov (United States)

    Glynn, Liam G; Glynn, Fergus; Casey, Monica; Wilkinson, Louise Gaffney; Hayes, Patrick S; Heaney, David; Murphy, Andrew W M

    2018-05-02

    Problematic translational gaps continue to exist between demonstrating the positive impact of healthcare interventions in research settings and their implementation into routine daily practice. The aim of this qualitative evaluation of the SMART MOVE trial was to conduct a theoretically informed analysis, using normalisation process theory, of the potential barriers and levers to the implementation of a mhealth intervention to promote physical activity in primary care. The study took place in the West of Ireland with recruitment in the community from the Clare Primary Care Network. SMART MOVE trial participants and the staff from four primary care centres were invited to take part and all agreed to do so. A qualitative methodology with a combination of focus groups (general practitioners, practice nurses and non-clinical staff from four separate primary care centres, n = 14) and individual semi-structured interviews (intervention and control SMART MOVE trial participants, n = 4) with purposeful sampling utilising the principles of Framework Analysis was utilised. The Normalisation Process Theory was used to develop the topic guide for the interviews and also informed the data analysis process. Four themes emerged from the analysis: personal and professional exercise strategies; roles and responsibilities to support active engagement; utilisation challenges; and evaluation, adoption and adherence. It was evident that introducing a new healthcare intervention demands a comprehensive evaluation of the intervention itself and also the environment in which it is to operate. Despite certain obstacles, the opportunity exists for the successful implementation of a novel healthcare intervention that addresses a hitherto unresolved healthcare need, provided that the intervention has strong usability attributes for both disseminators and target users and coheres strongly with the core objectives and culture of the health care environment in which it is to operate. We

  17. Interpreting conjunctions.

    Science.gov (United States)

    Bott, Lewis; Frisson, Steven; Murphy, Gregory L

    2009-04-01

    The interpretation generated from a sentence of the form P and Q can often be different to that generated by Q and P, despite the fact that and has a symmetric truth-conditional meaning. We experimentally investigated to what extent this difference in meaning is due to the connective and and to what extent it is due to order of mention of the events in the sentence. In three experiments, we collected interpretations of sentences in which we varied the presence of the conjunction, the order of mention of the events, and the type of relation holding between the events (temporally vs. causally related events). The results indicated that the effect of using a conjunction was dependent on the discourse relation between the events. Our findings contradict a narrative marker theory of and, but provide partial support for a single-unit theory derived from Carston (2002). The results are discussed in terms of conjunction processing and implicatures of temporal order.

  18. Technical Note: On methodologies for determining the size-normalised weight of planktic foraminifera

    Directory of Open Access Journals (Sweden)

    C. J. Beer

    2010-07-01

    Full Text Available The size-normalised weight (SNW of planktic foraminifera, a measure of test wall thickness and density, is potentially a valuable palaeo-proxy for marine carbon chemistry. As increasing attention is given to developing this proxy it is important that methods are comparable between studies. Here, we compare SNW data generated using two different methods to account for variability in test size, namely (i the narrow (50 μm range sieve fraction method and (ii the individually measured test size method. Using specimens from the 200–250 μm sieve fraction range collected in multinet samples from the North Atlantic, we find that sieving does not constrain size sufficiently well to isolate changes in weight driven by variations in test wall thickness and density from those driven by size. We estimate that the SNW data produced as part of this study are associated with an uncertainty, or error bar, of about ±11%. Errors associated with the narrow sieve fraction method may be reduced by decreasing the size of the sieve window, by using larger tests and by increasing the number tests employed. In situations where numerous large tests are unavailable, however, substantial errors associated with this sieve method remain unavoidable. In such circumstances the individually measured test size method provides a better means for estimating SNW because, as our results show, this method isolates changes in weight driven by variations in test wall thickness and density from those driven by size.

  19. No upward trend in normalised windstorm losses in Europe: 1970-2008

    Science.gov (United States)

    Barredo, J. I.

    2010-01-01

    On 18 January 2007, windstorm Kyrill battered Europe with hurricane-force winds killing 47 people and causing 10 billion US in damage. Kyrill poses several questions: is Kyrill an isolated or exceptional case? Have there been events costing as much in the past? This paper attempts to put Kyrill into an historical context by examining large historical windstorm event losses in Europe for the period 1970-2008 across 29 European countries. It asks the question what economic losses would these historical events cause if they were to recur under 2008 societal conditions? Loss data were sourced from reinsurance firms and augmented with historical reports, peer-reviewed articles and other ancillary sources. Following the same conceptual approach outlined in previous studies, the data were then adjusted for changes in population, wealth, and inflation at the country level and for inter-country price differences using purchasing power parity. The analyses reveal no trend in the normalised windstorm losses and confirm increasing disaster losses are driven by societal factors and increasing exposure.

  20. Normalised Mutual Information of High-Density Surface Electromyography during Muscle Fatigue

    Directory of Open Access Journals (Sweden)

    Adrian Bingham

    2017-12-01

    Full Text Available This study has developed a technique for identifying the presence of muscle fatigue based on the spatial changes of the normalised mutual information (NMI between multiple high density surface electromyography (HD-sEMG channels. Muscle fatigue in the tibialis anterior (TA during isometric contractions at 40% and 80% maximum voluntary contraction levels was investigated in ten healthy participants (Age range: 21 to 35 years; Mean age = 26 years; Male = 4, Female = 6. HD-sEMG was used to record 64 channels of sEMG using a 16 by 4 electrode array placed over the TA. The NMI of each electrode with every other electrode was calculated to form an NMI distribution for each electrode. The total NMI for each electrode (the summation of the electrode’s NMI distribution highlighted regions of high dependence in the electrode array and was observed to increase as the muscle fatigued. To summarise this increase, a function, M(k, was defined and was found to be significantly affected by fatigue and not by contraction force. The technique discussed in this study has overcome issues regarding electrode placement and was used to investigate how the dependences between sEMG signals within the same muscle change spatially during fatigue.

  1. Interpretive Medicine

    Science.gov (United States)

    Reeve, Joanne

    2010-01-01

    Patient-centredness is a core value of general practice; it is defined as the interpersonal processes that support the holistic care of individuals. To date, efforts to demonstrate their relationship to patient outcomes have been disappointing, whilst some studies suggest values may be more rhetoric than reality. Contextual issues influence the quality of patient-centred consultations, impacting on outcomes. The legitimate use of knowledge, or evidence, is a defining aspect of modern practice, and has implications for patient-centredness. Based on a critical review of the literature, on my own empirical research, and on reflections from my clinical practice, I critique current models of the use of knowledge in supporting individualised care. Evidence-Based Medicine (EBM), and its implementation within health policy as Scientific Bureaucratic Medicine (SBM), define best evidence in terms of an epistemological emphasis on scientific knowledge over clinical experience. It provides objective knowledge of disease, including quantitative estimates of the certainty of that knowledge. Whilst arguably appropriate for secondary care, involving episodic care of selected populations referred in for specialist diagnosis and treatment of disease, application to general practice can be questioned given the complex, dynamic and uncertain nature of much of the illness that is treated. I propose that general practice is better described by a model of Interpretive Medicine (IM): the critical, thoughtful, professional use of an appropriate range of knowledges in the dynamic, shared exploration and interpretation of individual illness experience, in order to support the creative capacity of individuals in maintaining their daily lives. Whilst the generation of interpreted knowledge is an essential part of daily general practice, the profession does not have an adequate framework by which this activity can be externally judged to have been done well. Drawing on theory related to the

  2. Objective interpretation as conforming interpretation

    OpenAIRE

    Lidka Rodak

    2011-01-01

    The practical discourse willingly uses the formula of “objective interpretation”, with no regards to its controversial nature that has been discussed in literature.The main aim of the article is to investigate what “objective interpretation” could mean and how it could be understood in the practical discourse, focusing on the understanding offered by judicature.The thesis of the article is that objective interpretation, as identified with textualists’ position, is not possible to uphold, and ...

  3. A combination of low-dose bevacizumab and imatinib enhances vascular normalisation without inducing extracellular matrix deposition.

    Science.gov (United States)

    Schiffmann, L M; Brunold, M; Liwschitz, M; Goede, V; Loges, S; Wroblewski, M; Quaas, A; Alakus, H; Stippel, D; Bruns, C J; Hallek, M; Kashkar, H; Hacker, U T; Coutelle, O

    2017-02-28

    Vascular endothelial growth factor (VEGF)-targeting drugs normalise the tumour vasculature and improve access for chemotherapy. However, excessive VEGF inhibition fails to improve clinical outcome, and successive treatment cycles lead to incremental extracellular matrix (ECM) deposition, which limits perfusion and drug delivery. We show here, that low-dose VEGF inhibition augmented with PDGF-R inhibition leads to superior vascular normalisation without incremental ECM deposition thus maintaining access for therapy. Collagen IV expression was analysed in response to VEGF inhibition in liver metastasis of colorectal cancer (CRC) patients, in syngeneic (Panc02) and xenograft tumours of human colorectal cancer cells (LS174T). The xenograft tumours were treated with low (0.5 mg kg -1 body weight) or high (5 mg kg -1 body weight) doses of the anti-VEGF antibody bevacizumab with or without the tyrosine kinase inhibitor imatinib. Changes in tumour growth, and vascular parameters, including microvessel density, pericyte coverage, leakiness, hypoxia, perfusion, fraction of vessels with an open lumen, and type IV collagen deposition were compared. ECM deposition was increased after standard VEGF inhibition in patients and tumour models. In contrast, treatment with low-dose bevacizumab and imatinib produced similar growth inhibition without inducing detrimental collagen IV deposition, leading to superior vascular normalisation, reduced leakiness, improved oxygenation, more open vessels that permit perfusion and access for therapy. Low-dose bevacizumab augmented by imatinib selects a mature, highly normalised and well perfused tumour vasculature without inducing incremental ECM deposition that normally limits the effectiveness of VEGF targeting drugs.

  4. Identification of endogenous control genes for normalisation of real-time quantitative PCR data in colorectal cancer.

    LENUS (Irish Health Repository)

    Kheirelseid, Elrasheid A H

    2010-01-01

    BACKGROUND: Gene expression analysis has many applications in cancer diagnosis, prognosis and therapeutic care. Relative quantification is the most widely adopted approach whereby quantification of gene expression is normalised relative to an endogenously expressed control (EC) gene. Central to the reliable determination of gene expression is the choice of control gene. The purpose of this study was to evaluate a panel of candidate EC genes from which to identify the most stably expressed gene(s) to normalise RQ-PCR data derived from primary colorectal cancer tissue. RESULTS: The expression of thirteen candidate EC genes: B2M, HPRT, GAPDH, ACTB, PPIA, HCRT, SLC25A23, DTX3, APOC4, RTDR1, KRTAP12-3, CHRNB4 and MRPL19 were analysed in a cohort of 64 colorectal tumours and tumour associated normal specimens. CXCL12, FABP1, MUC2 and PDCD4 genes were chosen as target genes against which a comparison of the effect of each EC gene on gene expression could be determined. Data analysis using descriptive statistics, geNorm, NormFinder and qBasePlus indicated significant difference in variances between candidate EC genes. We determined that two genes were required for optimal normalisation and identified B2M and PPIA as the most stably expressed and reliable EC genes. CONCLUSION: This study identified that the combination of two EC genes (B2M and PPIA) more accurately normalised RQ-PCR data in colorectal tissue. Although these control genes might not be optimal for use in other cancer studies, the approach described herein could serve as a template for the identification of valid ECs in other cancer types.

  5. The one-dimensional normalised generalised equivalence theory (NGET) for generating equivalent diffusion theory group constants for PWR reflector regions

    International Nuclear Information System (INIS)

    Mueller, E.Z.

    1991-01-01

    An equivalent diffusion theory PWR reflector model is presented, which has as its basis Smith's generalisation of Koebke's Equivalent Theory. This method is an adaptation, in one-dimensional slab geometry, of the Generalised Equivalence Theory (GET). Since the method involves the renormalisation of the GET discontinuity factors at nodal interfaces, it is called the Normalised Generalised Equivalence Theory (NGET) method. The advantages of the NGET method for modelling the ex-core nodes of a PWR are summarized. 23 refs

  6. Good quality of oral anticoagulation treatment in general practice using international normalised ratio point of care testing

    DEFF Research Database (Denmark)

    Løkkegaard, Thomas; Pedersen, Tina Heidi; Lind, Bent

    2015-01-01

    INTRODUCTION: Oral anticoagulation treatment (OACT) with warfarin is common in general practice. Increasingly, international normalised ratio (INR) point of care testing (POCT) is being used to manage patients. The aim of this study was to describe and analyse the quality of OACT with warfarin...... practices using INR POCT in the management of patients in warfarin treatment provided good quality of care. Sampling interval and diagnostic coding were significantly correlated with treatment quality....

  7. Using Normalisation Process Theory to investigate the implementation of school-based oral health promotion.

    Science.gov (United States)

    Olajide, O J; Shucksmith, J; Maguire, A; Zohoori, F V

    2017-09-01

    Despite the considerable improvement in oral health of children in the UK over the last forty years, a significant burden of dental caries remains prevalent in some groups of children, indicating the need for more effective oral health promotion intervention (OHPI) strategies in this population. To explore the implementation process of a community-based OHPI, in the North East of England, using Normalisation Process Theory (NPT) to provide insights on how effectiveness could be maximised. Utilising a generic qualitative research approach, 19 participants were recruited into the study. In-depth interviews were conducted with relevant National Health Service (NHS) staff and primary school teachers while focus group discussions were conducted with reception teachers and teaching assistants. Analyses were conducted using thematic analysis with emergent themes mapped onto NPT constructs. Participants highlighted the benefits of OHPI and the need for evidence in practice. However, implementation of 'best evidence' was hampered by lack of adequate synthesis of evidence from available clinical studies on effectiveness of OHPI as these generally have insufficient information on the dynamics of implementation and how effectiveness obtained in clinical studies could be achieved in 'real life'. This impacted on the decision-making process, levels of commitment, collaboration among OHP teams, resource allocation and evaluation of OHPI. A large gap exists between available research evidence and translation of evidence in OHPI in community settings. Effectiveness of OHPI requires not only an awareness of evidence of clinical effectiveness but also synthesised information about change mechanisms and implementation protocols. Copyright© 2017 Dennis Barber Ltd.

  8. Diabetic ketoacidosis in adult patients: an audit of factors influencing time to normalisation of metabolic parameters.

    Science.gov (United States)

    Lee, Melissa H; Calder, Genevieve L; Santamaria, John D; MacIsaac, Richard J

    2018-05-01

    Diabetic ketoacidosis (DKA) is an acute life-threatening metabolic complication of diabetes that imposes substantial burden on our healthcare system. There is a paucity of published data in Australia assessing factors influencing time to resolution of DKA and length of stay (LOS). To identify factors that predict a slower time to resolution of DKA in adults with diabetes. Retrospective audit of patients admitted to St Vincent's Hospital Melbourne between 2010 to 2014 coded with a diagnosis of 'Diabetic Ketoacidosis'. The primary outcome was time to resolution of DKA based on normalisation of biochemical markers. Episodes of DKA within the wider Victorian hospital network were also explored. Seventy-one patients met biochemical criteria for DKA; median age 31 years (26-45 years), 59% were male and 23% had newly diagnosed diabetes. Insulin omission was the most common precipitant (42%). Median time to resolution of DKA was 11 h (6.5-16.5 h). Individual factors associated with slower resolution of DKA were lower admission pH (P < 0.001) and higher admission serum potassium level (P = 0.03). Median LOS was 3 days (2-5 days), compared to a Victorian state-wide LOS of 2 days. Higher comorbidity scores were associated with longer LOS (P < 0.001). Lower admission pH levels and higher admission serum potassium levels are independent predictors of slower time to resolution of DKA. This may assist to stratify patients with DKA using markers of severity to determine who may benefit from closer monitoring and to predict LOS. © 2018 Royal Australasian College of Physicians.

  9. Quantification of tumour {sup 18}F-FDG uptake: Normalise to blood glucose or scale to liver uptake?

    Energy Technology Data Exchange (ETDEWEB)

    Keramida, Georgia [Brighton and Sussex Medical School, Clinical Imaging Sciences Centre, Brighton (United Kingdom); Brighton and Sussex University Hospitals NHS Trust, Department of Nuclear Medicine, Brighton (United Kingdom); University of Sussex, Clinical Imaging Sciences Centre, Brighton (United Kingdom); Dizdarevic, Sabina; Peters, A.M. [Brighton and Sussex Medical School, Clinical Imaging Sciences Centre, Brighton (United Kingdom); Brighton and Sussex University Hospitals NHS Trust, Department of Nuclear Medicine, Brighton (United Kingdom); Bush, Janice [Brighton and Sussex Medical School, Clinical Imaging Sciences Centre, Brighton (United Kingdom)

    2015-09-15

    To compare normalisation to blood glucose (BG) with scaling to hepatic uptake for quantification of tumour {sup 18}F-FDG uptake using the brain as a surrogate for tumours. Standardised uptake value (SUV) was measured over the liver, cerebellum, basal ganglia, and frontal cortex in 304 patients undergoing {sup 18}F-FDG PET/CT. The relationship between brain FDG clearance and SUV was theoretically defined. Brain SUV decreased exponentially with BG, with similar constants between cerebellum, basal ganglia, and frontal cortex (0.099-0.119 mmol/l{sup -1}) and similar to values for tumours estimated from the literature. Liver SUV, however, correlated positively with BG. Brain-to-liver SUV ratio therefore showed an inverse correlation with BG, well-fitted with a hyperbolic function (R = 0.83), as theoretically predicted. Brain SUV normalised to BG (nSUV) displayed a nonlinear correlation with BG (R = 0.55); however, as theoretically predicted, brain nSUV/liver SUV showed almost no correlation with BG. Correction of brain SUV using BG raised to an exponential power of 0.099 mmol/l{sup -1} also eliminated the correlation between brain SUV and BG. Brain SUV continues to correlate with BG after normalisation to BG. Likewise, liver SUV is unsuitable as a reference for tumour FDG uptake. Brain SUV divided by liver SUV, however, shows minimal dependence on BG. (orig.)

  10. Analysis of a simulated microarray dataset: Comparison of methods for data normalisation and detection of differential expression (Open Access publication

    Directory of Open Access Journals (Sweden)

    Mouzaki Daphné

    2007-11-01

    Full Text Available Abstract Microarrays allow researchers to measure the expression of thousands of genes in a single experiment. Before statistical comparisons can be made, the data must be assessed for quality and normalisation procedures must be applied, of which many have been proposed. Methods of comparing the normalised data are also abundant, and no clear consensus has yet been reached. The purpose of this paper was to compare those methods used by the EADGENE network on a very noisy simulated data set. With the a priori knowledge of which genes are differentially expressed, it is possible to compare the success of each approach quantitatively. Use of an intensity-dependent normalisation procedure was common, as was correction for multiple testing. Most variety in performance resulted from differing approaches to data quality and the use of different statistical tests. Very few of the methods used any kind of background correction. A number of approaches achieved a success rate of 95% or above, with relatively small numbers of false positives and negatives. Applying stringent spot selection criteria and elimination of data did not improve the false positive rate and greatly increased the false negative rate. However, most approaches performed well, and it is encouraging that widely available techniques can achieve such good results on a very noisy data set.

  11. OpenPrescribing: normalised data and software tool to research trends in English NHS primary care prescribing 1998-2016.

    Science.gov (United States)

    Curtis, Helen J; Goldacre, Ben

    2018-02-23

    We aimed to compile and normalise England's national prescribing data for 1998-2016 to facilitate research on long-term time trends and create an open-data exploration tool for wider use. We compiled data from each individual year's national statistical publications and normalised them by mapping each drug to its current classification within the national formulary where possible. We created a freely accessible, interactive web tool to allow anyone to interact with the processed data. We downloaded all available annual prescription cost analysis datasets, which include cost and quantity for all prescription items dispensed in the community in England. Medical devices and appliances were excluded. We measured the extent of normalisation of data and aimed to produce a functioning accessible analysis tool. All data were imported successfully. 87.5% of drugs were matched exactly on name to the current formulary and a further 6.5% to similar drug names. All drugs in core clinical chapters were reconciled to their current location in the data schema, with only 1.26% of drugs not assigned a current chemical code. We created an openly accessible interactive tool to facilitate wider use of these data. Publicly available data can be made accessible through interactive online tools to help researchers and policy-makers explore time trends in prescribing. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  12. Mammographic interpretation

    International Nuclear Information System (INIS)

    Tabor, L.

    1987-01-01

    For mammography to be an effective diagnostic method, it must be performed to a very high standard of quality. Otherwise many lesions, in particular cancer in its early stages, will simply not be detectable on the films, regardless of the skill of the mammographer. Mammographic interpretation consists of two basic steps: perception and analysis. The process of mammographic interpretation begins with perception of the lesion on the mammogram. Perception is influenced by several factors. One of the most important is the parenchymal pattern of the breast tissue, detection of pathologic lesions being easier with fatty involution. The mammographer should use a method for the systematic viewing of the mammograms that will ensure that all parts of each mammogram are carefully searched for the presence of lesions. The method of analysis proceeds according to the type of lesion. The contour analysis of primary importance in the evaluation of circumscribed tumors. After having analyzed the contour and density of a lesion and considered its size, the mammographer should be fairly certain whether the circumscribed tumor is benign or malignant. Fine-needle puncture and/or US may assist the mammographer in making this decision. Painstaking analysis is required because many circumscribed tumors do not need to be biopsied. The perception of circumscribed tumors seldom causes problems, but their analysis needs careful attention. On the other hand, the major challenge with star-shaped lesions is perception. They may be difficult to discover when small. Although the final diagnosis of a stellate lesion can be made only with the help of histologic examination, the preoperative mammorgraphic differential diagnosis can be highly accurate. The differential diagnostic problem is between malignant tumors (scirrhous carcinoma), on the one hand, and traumatic fat necrosis as well as radial scars on the other hand

  13. New Evidence of Regional Geological Structures Inferred from Reprocessing and Resistivity Data Interpretation in the Chingshui-Sanshing-Hanchi Area of Southwestern Ilan County, NE Taiwan

    Directory of Open Access Journals (Sweden)

    Gong-Ruei Ho

    2014-01-01

    Full Text Available The Ilan Plain is located at the southwestern tip of the back arc basin of the Okinawa Trough, which propagates westward into the Taiwan orogen. A long discussed issue concerns whether the opening normal-fault system of the Okinawa Trough propagates and transforms into the thrust-fault system of the Taiwan orogen. We have reprocessed and inverted resistivity measurements from a series of surveys conducted in the 1970s around the Chingshui-Sanshing-Hanchi area of southwestern Ilan County. The 2D and 3D inverted resistivity images reveal the regional structures. A major conductive structure dipping toward the northwest at an angle of 30° - 40° is located at the expected site of the Niudou Fault separating the Early Miocene Szeleng and Kangkou Formations from the Lushan Formation in the Sanshing area, which dip direction of two conductive structures with a dipping angle of 50° - 70° were coinciding with the dip direction of normal faults identified from the field surveys. In addition three high-angle discontinuity structures, dipping toward the north with an angle of 60° - 80° can be identified in the resistivity profile along Hanchi. We tend to suggest these structures as the extended portions of the normal faults that have been identified under the unconsolidated sediments in the Ilan Plain. Resistivity profiles from the Chingshuichi area reveal the existence of the vertical Chingshuichi, the Dachi, and the Xiaonanauo Fault. Hot springs were found in the junction area of the Chingshuichi and the Xiaonanauo Fault. The junction region of these two fault systems is the potential Chingshui geothermal field that provides fluid geothermals from the deep.

  14. An Interpreter's Interpretation: Sign Language Interpreters' View of Musculoskeletal Disorders

    National Research Council Canada - National Science Library

    Johnson, William L

    2003-01-01

    Sign language interpreters are at increased risk for musculoskeletal disorders. This study used content analysis to obtain detailed information about these disorders from the interpreters' point of view...

  15. The implementation of medical revalidation: an assessment using normalisation process theory

    Directory of Open Access Journals (Sweden)

    Abigail Tazzyman

    2017-11-01

    Full Text Available Abstract Background Medical revalidation is the process by which all licensed doctors are legally required to demonstrate that they are up to date and fit to practise in order to maintain their licence. Revalidation was introduced in the United Kingdom (UK in 2012, constituting significant change in the regulation of doctors. The governing body, the General Medical Council (GMC, envisages that revalidation will improve patient care and safety. This potential however is, in part, dependent upon how successfully revalidation is embedded into routine practice. The aim of this study was to use Normalisation Process Theory (NPT to explore issues contributing to or impeding the implementation of revalidation in practice. Methods We conducted seventy-one interviews with sixty UK policymakers and senior leaders at different points during the development and implementation of revalidation: in 2011 (n = 31, 2013 (n = 26 and 2015 (n = 14. We selected interviewees using purposeful sampling. NPT was used as a framework to enable systematic analysis across the interview sets. Results Initial lack of consensus over revalidation’s purpose, and scepticism about its value, decreased over time as participants recognised the benefits it brought to their practice (coherence category of NPT. Though acceptance increased across time, revalidation was not seen as a legitimate part of their role by all doctors. Key individuals, notably the Responsible Officer (RO, were vital for the successful implementation of revalidation in organisations (cognitive participation category. The ease with which revalidation could be integrated into working practices varied greatly depending on the type of role a doctor held and the organisation they work for and the provision of resources was a significant variable in this (collective action category. Formal evaluation of revalidation in organisations was lacking but informal evaluation was taking place. Revalidation had

  16. Trends of air pollution in Denmark - Normalised by a simple weather index model

    International Nuclear Information System (INIS)

    Kiilsholm, S.; Rasmussen, A.

    2000-01-01

    This report is a part of the Traffic Pool projects on 'Traffic and Environments', 1995-99, financed by the Danish Ministry of Transport. The Traffic Pool projects included five different projects on 'Surveillance of the Air Quality', 'Atmospheric Modelling', 'Atmospheric Chemistry Modelling', 'Smog and ozone' and 'Greenhouse effects and Climate', [Rasmussen, 2000]. This work is a part of the project on 'Surveillance of the Air Quality' with the main objectives to make trend analysis of levels of air pollution from traffic in Denmark. Other participants were from the Road Directory mainly focusing on measurement of traffic and trend analysis of the air quality utilising a nordic model for the air pollution in street canyons called BLB (Beregningsmodel for Luftkvalitet i Byluftgader) [Vejdirektoratet 2000], National Environmental Research Institute (HERI) mainly focusing on. measurements of air pollution and trend analysis with the Operational Street Pollution Model (OSPM) [DMU 2000], and the Copenhagen Environmental Protection Agency mainly focusing on measurements. In this study a more simple statistical model has been developed for trend analysis of the air quality. The model is filtering out the influence of the variations from year to year in the meteorological conditions on the air pollution levels. The weather factors found most important are wind speed, wind direction and mixing height. Measurements of CO, NO and NO 2 from three streets in Copenhagen have been used, these streets are Jagtvej, Bredgade and H. C. Andersen's Boulevard (HCAB). The years 1994-1996 were used for evaluation of the method and annual indexes of air pollution index dependent only on meteorological parameters, called WEATHIX, were calculated for the years 1990-1997 and used for normalisation of the observed air pollution trends. Meteorological data were taken from either the background stations at the H.C. Oersted - building situated close to one of the street stations or the synoptic

  17. Interpreting the Customary Rules on Interpretation

    NARCIS (Netherlands)

    Merkouris, Panos

    2017-01-01

    International courts have at times interpreted the customary rules on interpretation. This is interesting because what is being interpreted is: i) rules of interpretation, which sounds dangerously tautological, and ii) customary law, the interpretation of which has not been the object of critical

  18. Can Linear Regression Modeling Help Clinicians in the Interpretation of Genotypic Resistance Data? An Application to Derive a Lopinavir-Score

    DEFF Research Database (Denmark)

    Cozzi-Lepri, Alessandro; Prosperi, Mattia C F; Kjær, Jesper

    2011-01-01

    explored the potential of linear regression to construct a simple predictive model for lopinavir/r-based TCE. Although, the performance of our proposed score was similar to that of already existing IS, previously unrecognized lopinavir/r-associated mutations were identified. The analysis illustrates......BACKGROUND: The question of whether a score for a specific antiretroviral (e.g. lopinavir/r in this analysis) that improves prediction of viral load response given by existing expert-based interpretation systems (IS) could be derived from analyzing the correlation between genotypic data......). Our analysis identified mutations V82A, I54V, K20I and I62V, which were associated with reduced viral response and mutations I15V and V91S which determined lopinavir/r hypersensitivity. All models performed equally well (ASE on test ranging between 1.1 and 1.3, p¿=¿0.34). CONCLUSIONS: We fully...

  19. Towards Better Precision Medicine: PacBio Single-Molecule Long Reads Resolve the Interpretation of HIV Drug Resistant Mutation Profiles at Explicit Quasispecies (Haplotype) Level.

    Science.gov (United States)

    Huang, Da Wei; Raley, Castle; Jiang, Min Kang; Zheng, Xin; Liang, Dun; Rehman, M Tauseef; Highbarger, Helene C; Jiao, Xiaoli; Sherman, Brad; Ma, Liang; Chen, Xiaofeng; Skelly, Thomas; Troyer, Jennifer; Stephens, Robert; Imamichi, Tomozumi; Pau, Alice; Lempicki, Richard A; Tran, Bao; Nissley, Dwight; Lane, H Clifford; Dewar, Robin L

    2016-01-01

    Development of HIV-1 drug resistance mutations (HDRMs) is one of the major reasons for the clinical failure of antiretroviral therapy. Treatment success rates can be improved by applying personalized anti-HIV regimens based on a patient's HDRM profile. However, the sensitivity and specificity of the HDRM profile is limited by the methods used for detection. Sanger-based sequencing technology has traditionally been used for determining HDRM profiles at the single nucleotide variant (SNV) level, but with a sensitivity of only ≥ 20% in the HIV population of a patient. Next Generation Sequencing (NGS) technologies offer greater detection sensitivity (~ 1%) and larger scope (hundreds of samples per run). However, NGS technologies produce reads that are too short to enable the detection of the physical linkages of individual SNVs across the haplotype of each HIV strain present. In this article, we demonstrate that the single-molecule long reads generated using the Third Generation Sequencer (TGS), PacBio RS II, along with the appropriate bioinformatics analysis method, can resolve the HDRM profile at a more advanced quasispecies level. The case studies on patients' HIV samples showed that the quasispecies view produced using the PacBio method offered greater detection sensitivity and was more comprehensive for understanding HDRM situations, which is complement to both Sanger and NGS technologies. In conclusion, the PacBio method, providing a promising new quasispecies level of HDRM profiling, may effect an important change in the field of HIV drug resistance research.

  20. Preoperative mapping of cortical language areas in adult brain tumour patients using PET and individual non-normalised SPM analyses

    International Nuclear Information System (INIS)

    Meyer, Philipp T.; Sturz, Laszlo; Schreckenberger, Mathias; Setani, Keyvan S.; Buell, Udalrich; Spetzger, Uwe; Meyer, Georg F.; Sabri, Osama

    2003-01-01

    In patients scheduled for the resection of perisylvian brain tumours, knowledge of the cortical topography of language functions is crucial in order to avoid neurological deficits. We investigated the applicability of statistical parametric mapping (SPM) without stereotactic normalisation for individual preoperative language function brain mapping using positron emission tomography (PET). Seven right-handed adult patients with left-sided brain tumours (six frontal and one temporal) underwent 12 oxygen-15 labelled water PET scans during overt verb generation and rest. Individual activation maps were calculated for P<0.005 and P<0.001 without anatomical normalisation and overlaid onto the individuals' magnetic resonance images for preoperative planning. Activations corresponding to Broca's and Wernicke's areas were found in five and six cases, respectively, for P<0.005 and in three and six cases, respectively, for P<0.001. One patient with a glioma located in the classical Broca's area without aphasic symptoms presented an activation of the adjacent inferior frontal cortex and of a right-sided area homologous to Broca's area. Four additional patients with left frontal tumours also presented activations of the right-sided Broca's homologue; two of these showed aphasic symptoms and two only a weak or no activation of Broca's area. Other frequently observed activations included bilaterally the superior temporal gyri, prefrontal cortices, anterior insulae, motor areas and the cerebellum. The middle and inferior temporal gyri were activated predominantly on the left. An SPM group analysis (P<0.05, corrected) in patients with left frontal tumours confirmed the activation pattern shown by the individual analyses. We conclude that SPM analyses without stereotactic normalisation offer a promising alternative for analysing individual preoperative language function brain mapping studies. The observed right frontal activations agree with proposed reorganisation processes, but

  1. Good quality of oral anticoagulation treatment in general practice using international normalised ratio point of care testing

    DEFF Research Database (Denmark)

    Løkkegaard, Thomas; Pedersen, Tina Heidi; Lind, Bent

    2015-01-01

    collected retrospectively for a period of six months. For each patient, time in therapeutic range (TTR) was calculated and correlated with practice and patient characteristics using multilevel linear regression models. RESULTS: We identified 447 patients in warfarin treatment in the 20 practices using POCT......INTRODUCTION: Oral anticoagulation treatment (OACT) with warfarin is common in general practice. Increasingly, international normalised ratio (INR) point of care testing (POCT) is being used to manage patients. The aim of this study was to describe and analyse the quality of OACT with warfarin...

  2. Good quality of oral anticoagulation treatment in general practice using international normalised ratio point of care testing

    DEFF Research Database (Denmark)

    Løkkegaard, Thomas; Pedersen, Tina Heidi; Lind, Bent

    2015-01-01

    INTRODUCTION: Oral anticoagulation treatment (OACT)with warfarin is common in general practice. Increasingly,international normalised ratio (INR) point of care testing(POCT) is being used to manage patients. The aim of thisstudy was to describe and analyse the quality of OACT withwarfarin...... in the management of patients in warfarintreatment provided good quality of care. Sampling intervaland diagnostic coding were significantly correlated withtreatment quality. FUNDING: The study received financial support from theSarah Krabbe Foundation, the General Practitioners’ Educationand Development Foundation...

  3. Calculation of normalised organ and effective doses to adult reference computational phantoms from contemporary computed tomography scanners

    International Nuclear Information System (INIS)

    Jansen, Jan T.M.; Shrimpton, Paul C.

    2010-01-01

    The general-purpose Monte Carlo radiation transport code MCNPX has been used to simulate photon transport and energy deposition in anthropomorphic phantoms due to the x-ray exposure from the Philips iCT 256 and Siemens Definition CT scanners, together with the previously studied General Electric 9800. The MCNPX code was compiled with the Intel FORTRAN compiler and run on a Linux PC cluster. A patch has been successfully applied to reduce computing times by about 4%. The International Commission on Radiological Protection (ICRP) has recently published the Adult Male (AM) and Adult Female (AF) reference computational voxel phantoms as successors to the Medical Internal Radiation Dose (MIRD) stylised hermaphrodite mathematical phantoms that form the basis for the widely-used ImPACT CT dosimetry tool. Comparisons of normalised organ and effective doses calculated for a range of scanner operating conditions have demonstrated significant differences in results (in excess of 30%) between the voxel and mathematical phantoms as a result of variations in anatomy. These analyses illustrate the significant influence of choice of phantom on normalised organ doses and the need for standardisation to facilitate comparisons of dose. Further such dose simulations are needed in order to update the ImPACT CT Patient Dosimetry spreadsheet for contemporary CT practice. (author)

  4. 18S rRNA is a reliable normalisation gene for real time PCR based on influenza virus infected cells

    Directory of Open Access Journals (Sweden)

    Kuchipudi Suresh V

    2012-10-01

    Full Text Available Abstract Background One requisite of quantitative reverse transcription PCR (qRT-PCR is to normalise the data with an internal reference gene that is invariant regardless of treatment, such as virus infection. Several studies have found variability in the expression of commonly used housekeeping genes, such as beta-actin (ACTB and glyceraldehyde-3-phosphate dehydrogenase (GAPDH, under different experimental settings. However, ACTB and GAPDH remain widely used in the studies of host gene response to virus infections, including influenza viruses. To date no detailed study has been described that compares the suitability of commonly used housekeeping genes in influenza virus infections. The present study evaluated several commonly used housekeeping genes [ACTB, GAPDH, 18S ribosomal RNA (18S rRNA, ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide (ATP5B and ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9 (ATP5G1] to identify the most stably expressed gene in human, pig, chicken and duck cells infected with a range of influenza A virus subtypes. Results The relative expression stability of commonly used housekeeping genes were determined in primary human bronchial epithelial cells (HBECs, pig tracheal epithelial cells (PTECs, and chicken and duck primary lung-derived cells infected with five influenza A virus subtypes. Analysis of qRT-PCR data from virus and mock infected cells using NormFinder and BestKeeper software programmes found that 18S rRNA was the most stable gene in HBECs, PTECs and avian lung cells. Conclusions Based on the presented data from cell culture models (HBECs, PTECs, chicken and duck lung cells infected with a range of influenza viruses, we found that 18S rRNA is the most stable reference gene for normalising qRT-PCR data. Expression levels of the other housekeeping genes evaluated in this study (including ACTB and GPADH were highly affected by influenza virus infection and

  5. Interpretive Media Study and Interpretive Social Science.

    Science.gov (United States)

    Carragee, Kevin M.

    1990-01-01

    Defines the major theoretical influences on interpretive approaches in mass communication, examines the central concepts of these perspectives, and provides a critique of these approaches. States that the adoption of interpretive approaches in mass communication has ignored varied critiques of interpretive social science. Suggests that critical…

  6. Interpreters, Interpreting, and the Study of Bilingualism.

    Science.gov (United States)

    Valdes, Guadalupe; Angelelli, Claudia

    2003-01-01

    Discusses research on interpreting focused specifically on issues raised by this literature about the nature of bilingualism. Suggests research carried out on interpreting--while primarily produced with a professional audience in mind and concerned with improving the practice of interpreting--provides valuable insights about complex aspects of…

  7. From theory to 'measurement' in complex interventions: methodological lessons from the development of an e-health normalisation instrument.

    Science.gov (United States)

    Finch, Tracy L; Mair, Frances S; O'Donnell, Catherine; Murray, Elizabeth; May, Carl R

    2012-05-17

    Although empirical and theoretical understanding of processes of implementation in health care is advancing, translation of theory into structured measures that capture the complex interplay between interventions, individuals and context remain limited. This paper aimed to (1) describe the process and outcome of a project to develop a theory-based instrument for measuring implementation processes relating to e-health interventions; and (2) identify key issues and methodological challenges for advancing work in this field. A 30-item instrument (Technology Adoption Readiness Scale (TARS)) for measuring normalisation processes in the context of e-health service interventions was developed on the basis on Normalization Process Theory (NPT). NPT focuses on how new practices become routinely embedded within social contexts. The instrument was pre-tested in two health care settings in which e-health (electronic facilitation of healthcare decision-making and practice) was used by health care professionals. The developed instrument was pre-tested in two professional samples (N=46; N=231). Ratings of items representing normalisation 'processes' were significantly related to staff members' perceptions of whether or not e-health had become 'routine'. Key methodological challenges are discussed in relation to: translating multi-component theoretical constructs into simple questions; developing and choosing appropriate outcome measures; conducting multiple-stakeholder assessments; instrument and question framing; and more general issues for instrument development in practice contexts. To develop theory-derived measures of implementation process for progressing research in this field, four key recommendations are made relating to (1) greater attention to underlying theoretical assumptions and extent of translation work required; (2) the need for appropriate but flexible approaches to outcomes measurement; (3) representation of multiple perspectives and collaborative nature of

  8. Aberrant brain responses to emotionally valent words is normalised after cognitive behavioural therapy in female depressed adolescents.

    Science.gov (United States)

    Chuang, Jie-Yu; J Whitaker, Kirstie; Murray, Graham K; Elliott, Rebecca; Hagan, Cindy C; Graham, Julia Me; Ooi, Cinly; Tait, Roger; Holt, Rosemary J; van Nieuwenhuizen, Adrienne O; Reynolds, Shirley; Wilkinson, Paul O; Bullmore, Edward T; Lennox, Belinda R; Sahakian, Barbara J; Goodyer, Ian; Suckling, John

    2016-01-01

    Depression in adolescence is debilitating with high recurrence in adulthood, yet its pathophysiological mechanism remains enigmatic. To examine the interaction between emotion, cognition and treatment, functional brain responses to sad and happy distractors in an affective go/no-go task were explored before and after Cognitive Behavioural Therapy (CBT) in depressed female adolescents, and healthy participants. Eighty-two Depressed and 24 healthy female adolescents, aged 12-17 years, performed a functional magnetic resonance imaging (fMRI) affective go/no-go task at baseline. Participants were instructed to withhold their responses upon seeing happy or sad words. Among these participants, 13 patients had CBT over approximately 30 weeks. These participants and 20 matched controls then repeated the task. At baseline, increased activation in response to happy relative to neutral distractors was observed in the orbitofrontal cortex in depressed patients which was normalised after CBT. No significant group differences were found behaviourally or in brain activation in response to sad distractors. Improvements in symptoms (mean: 9.31, 95% CI: 5.35-13.27) were related at trend-level to activation changes in orbitofrontal cortex. In the follow-up section, a limited number of post-CBT patients were recruited. To our knowledge, this is the first fMRI study addressing the effect of CBT in adolescent depression. Although a bias toward negative information is widely accepted as a hallmark of depression, aberrant brain hyperactivity to positive distractors was found and normalised after CBT. Research, assessment and treatment focused on positive stimuli could be a future consideration. Moreover, a pathophysiological mechanism distinct from adult depression may be suggested and awaits further exploration. Copyright © 2015 The Authors. Published by Elsevier B.V. All rights reserved.

  9. From theory to 'measurement' in complex interventions: Methodological lessons from the development of an e-health normalisation instrument

    Directory of Open Access Journals (Sweden)

    Finch Tracy L

    2012-05-01

    Full Text Available Abstract Background Although empirical and theoretical understanding of processes of implementation in health care is advancing, translation of theory into structured measures that capture the complex interplay between interventions, individuals and context remain limited. This paper aimed to (1 describe the process and outcome of a project to develop a theory-based instrument for measuring implementation processes relating to e-health interventions; and (2 identify key issues and methodological challenges for advancing work in this field. Methods A 30-item instrument (Technology Adoption Readiness Scale (TARS for measuring normalisation processes in the context of e-health service interventions was developed on the basis on Normalization Process Theory (NPT. NPT focuses on how new practices become routinely embedded within social contexts. The instrument was pre-tested in two health care settings in which e-health (electronic facilitation of healthcare decision-making and practice was used by health care professionals. Results The developed instrument was pre-tested in two professional samples (N = 46; N = 231. Ratings of items representing normalisation ‘processes’ were significantly related to staff members’ perceptions of whether or not e-health had become ‘routine’. Key methodological challenges are discussed in relation to: translating multi-component theoretical constructs into simple questions; developing and choosing appropriate outcome measures; conducting multiple-stakeholder assessments; instrument and question framing; and more general issues for instrument development in practice contexts. Conclusions To develop theory-derived measures of implementation process for progressing research in this field, four key recommendations are made relating to (1 greater attention to underlying theoretical assumptions and extent of translation work required; (2 the need for appropriate but flexible approaches to outcomes

  10. Rational parametrisation of normalised Stiefel manifolds, and explicit non-'t Hooft solutions of the Atiyah-Drinfeld-Hitchin-Manin instanton matrix equations for Sp(n)

    International Nuclear Information System (INIS)

    McCarthy, P.J.

    1981-01-01

    It is proved that normalised Stiefel manifolds admit a rational parametrisation which generalises Cayley's parametrisation of the unitary groups. Applying (the quaternionic case of) this parametrisation to the Atiyah-Drinfeld-Hitchin-Manin (ADHM) instanton matrix equations, large families of new explicit rational solutions emerge. In particular, new explicit non-'t Hooft solutions are presented. (orig.)

  11. A normalised seawater strontium isotope curve. Possible implications for Neoproterozoic-Cambrian weathering rates and the further oxygenation of the Earth

    International Nuclear Information System (INIS)

    Shields, G.A.

    2007-01-01

    The strontium isotope composition of seawater is strongly influenced on geological time scales by changes in the rates of continental weathering relative to ocean crust alteration. However, the potential of the seawater 87 Sr/ 86 Sr curve to trace globally integrated chemical weathering rates has not been fully realised because ocean 87 Sr/ 86 Sr is also influenced by the isotopic evolution of Sr sources to the ocean. A preliminary attempt is made here to normalise the seawater 87 Sr/ 86 Sr curve to plausible trends in the 87 Sr/ 86 Sr ratios of the three major Sr sources: carbonate dissolution, silicate weathering and submarine hydrothermal exchange. The normalised curve highlights the Neoproterozoic-Phanerozoic transition as a period of exceptionally high continental influence, indicating that this interval was characterised by a transient increase in global weathering rates and/or by the weathering of unusually radiogenic crustal rocks. Close correlation between the normalised 87 Sr/ 86 Sr curve, a published seawater δ 34 S curve and atmospheric pCO 2 models is used here to argue that elevated chemical weathering rates were a major contributing factor to the steep rise in seawater 87 Sr/ 86 Sr from 650 Ma to 500 Ma. Elevated weathering rates during the Neoproterozoic-Cambrian interval led to increased nutrient availability, organic burial and to the further oxygenation of Earth's surface environment. Use of normalised seawater 87 Sr/ 86 Sr curves will, it is hoped, help to improve future geochemical models of Earth System dynamics. (orig.)

  12. On court interpreters' visibility

    DEFF Research Database (Denmark)

    Dubslaff, Friedel; Martinsen, Bodil

    of the service they receive. Ultimately, the findings will be used for training purposes. Future - and, for that matter, already practising - interpreters as well as the professional users of interpreters ought to take the reality of the interpreters' work in practice into account when assessing the quality...... on the interpreter's interpersonal role and, in particular, on signs of the interpreter's visibility, i.e. active co-participation. At first sight, the interpreting assignment in question seems to be a short and simple routine task which would not require the interpreter to deviate from the traditional picture...

  13. Learning from doing: the case for combining normalisation process theory and participatory learning and action research methodology for primary healthcare implementation research.

    Science.gov (United States)

    de Brún, Tomas; O'Reilly-de Brún, Mary; O'Donnell, Catherine A; MacFarlane, Anne

    2016-08-03

    The implementation of research findings is not a straightforward matter. There are substantive and recognised gaps in the process of translating research findings into practice and policy. In order to overcome some of these translational difficulties, a number of strategies have been proposed for researchers. These include greater use of theoretical approaches in research focused on implementation, and use of a wider range of research methods appropriate to policy questions and the wider social context in which they are placed. However, questions remain about how to combine theory and method in implementation research. In this paper, we respond to these proposals. Focussing on a contemporary social theory, Normalisation Process Theory, and a participatory research methodology, Participatory Learning and Action, we discuss the potential of their combined use for implementation research. We note ways in which Normalisation Process Theory and Participatory Learning and Action are congruent and may therefore be used as heuristic devices to explore, better understand and support implementation. We also provide examples of their use in our own research programme about community involvement in primary healthcare. Normalisation Process Theory alone has, to date, offered useful explanations for the success or otherwise of implementation projects post-implementation. We argue that Normalisation Process Theory can also be used to prospectively support implementation journeys. Furthermore, Normalisation Process Theory and Participatory Learning and Action can be used together so that interventions to support implementation work are devised and enacted with the expertise of key stakeholders. We propose that the specific combination of this theory and methodology possesses the potential, because of their combined heuristic force, to offer a more effective means of supporting implementation projects than either one might do on its own, and of providing deeper understandings of

  14. Interpreting Impoliteness: Interpreters’ Voices

    Directory of Open Access Journals (Sweden)

    Tatjana Radanović Felberg

    2017-11-01

    Full Text Available Interpreters in the public sector in Norway interpret in a variety of institutional encounters, and the interpreters evaluate the majority of these encounters as polite. However, some encounters are evaluated as impolite, and they pose challenges when it comes to interpreting impoliteness. This issue raises the question of whether interpreters should take a stance on their own evaluation of impoliteness and whether they should interfere in communication. In order to find out more about how interpreters cope with this challenge, in 2014 a survey was sent to all interpreters registered in the Norwegian Register of Interpreters. The survey data were analyzed within the theoretical framework of impoliteness theory using the notion of moral order as an explanatory tool in a close reading of interpreters’ answers. The analysis shows that interpreters reported using a variety of strategies for interpreting impoliteness, including omissions and downtoning. However, the interpreters also gave examples of individual strategies for coping with impoliteness, such as interrupting and postponing interpreting. These strategies border behavioral strategies and conflict with the Norwegian ethical guidelines for interpreting. In light of the ethical guidelines and actual practice, mapping and discussing different strategies used by interpreters might heighten interpreters’ and interpreter-users’ awareness of the role impoliteness can play in institutional interpreter– mediated encounters. 

  15. Evaluation of electrical resistivity anisotropy in geological mapping ...

    African Journals Online (AJOL)

    user

    Key words: Electrical resistivity anisotropy, radial vertical electrical sounding, anisotropy polygons. INTRODUCTION ... electrical resistivity survey in the geological interpretation ... resistivity and other electrical or electromagnetic based.

  16. Normalisation of cerebrospinal fluid biomarkers parallels improvement of neurological symptoms following HAART in HIV dementia – case report

    Directory of Open Access Journals (Sweden)

    Blennow Kaj

    2006-09-01

    Full Text Available Abstract Background Since the introduction of HAART the incidence of HIV dementia has declined and HAART seems to improve neurocognitive function in patients with HIV dementia. Currently, HIV dementia develops mainly in patients without effective treatment, though it has also been described in patients on HAART and milder HIV-associated neuropsychological impairment is still frequent among HIV-1 infected patients regardless of HAART. Elevated cerebrospinal fluid (CSF levels of markers of neural injury and immune activation have been found in HIV dementia, but neither of those, nor CSF HIV-1 RNA levels have been proven useful as diagnostic or prognostic pseudomarkers in HIV dementia. Case presentation We report a case of HIV dementia (MSK stage 3 in a 57 year old antiretroviral naïve man who was introduced on zidovudine, lamivudine and ritonavir boosted indinavir, and followed with consecutive lumbar punctures before and after two and 15 months after initiation of HAART. Improvement of neurocognitive function was paralleled by normalisation of CSF neural markers (NFL, Tau and GFAP levels and a decline in CSF and serum neopterin and CSF and plasma HIV-1 RNA levels. Conclusion The value of these CSF markers as prognostic pseudomarkers of the effect of HAART on neurocognitive impairment in HIV dementia ought to be evaluated in longitudinal studies.

  17. Genre and Interpretation

    DEFF Research Database (Denmark)

    Auken, Sune

    2015-01-01

    Despite the immensity of genre studies as well as studies in interpretation, our understanding of the relationship between genre and interpretation is sketchy at best. The article attempts to unravel some of intricacies of that relationship through an analysis of the generic interpretation carrie...

  18. Engineering Definitional Interpreters

    DEFF Research Database (Denmark)

    Midtgaard, Jan; Ramsay, Norman; Larsen, Bradford

    2013-01-01

    A definitional interpreter should be clear and easy to write, but it may run 4--10 times slower than a well-crafted bytecode interpreter. In a case study focused on implementation choices, we explore ways of making definitional interpreters faster without expending much programming effort. We imp...

  19. Night-time restricted feeding normalises clock genes and Pai-1 gene expression in the db/db mouse liver.

    Science.gov (United States)

    Kudo, T; Akiyama, M; Kuriyama, K; Sudo, M; Moriya, T; Shibata, S

    2004-08-01

    An increase in PAI-1 activity is thought to be a key factor underlying myocardial infarction. Mouse Pai-1 (mPai-1) activity shows a daily rhythm in vivo, and its transcription seems to be controlled not only by clock genes but also by humoral factors such as insulin and triglycerides. Thus, we investigated daily clock genes and mPai-1 mRNA expression in the liver of db/db mice exhibiting high levels of glucose, insulin and triglycerides. Locomotor activity was measured using an infrared detection system. RT-PCR or in situ hybridisation methods were applied to measure gene expression. Humoral factors were measured using measurement kits. The db/ db mice showed attenuated locomotor activity rhythms. The rhythmic expression of mPer2 mRNA was severely diminished and the phase of mBmal1 oscillation was advanced in the db/db mouse liver, whereas mPai-1 mRNA was highly and constitutively expressed. Night-time restricted feeding led to a recovery not only from the diminished locomotor activity, but also from the diminished Per2 and advanced mBmal1 mRNA rhythms. Expression of mPai-1 mRNA in db/db mice was reduced to levels far below normal. Pioglitazone treatment slightly normalised glucose and insulin levels, with a slight reduction in mPai-1 gene expression. We demonstrated that Type 2 diabetes impairs the oscillation of the peripheral oscillator. Night-time restricted feeding rather than pioglitazone injection led to a recovery from the diminished locomotor activity, and altered oscillation of the peripheral clock and mPai-1 mRNA rhythm. Thus, we conclude that scheduled restricted food intake may be a useful form of treatment for diabetes.

  20. Analysis of a normalised expressed sequence tag (EST) library from a key pollinator, the bumblebee Bombus terrestris.

    Science.gov (United States)

    Sadd, Ben M; Kube, Michael; Klages, Sven; Reinhardt, Richard; Schmid-Hempel, Paul

    2010-02-15

    The bumblebee, Bombus terrestris (Order Hymenoptera), is of widespread importance. This species is extensively used for commercial pollination in Europe, and along with other Bombus spp. is a key member of natural pollinator assemblages. Furthermore, the species is studied in a wide variety of biological fields. The objective of this project was to create a B. terrestris EST resource that will prove to be valuable in obtaining a deeper understanding of this significant social insect. A normalised cDNA library was constructed from the thorax and abdomen of B. terrestris workers in order to enhance the discovery of rare genes. A total of 29'428 ESTs were sequenced. Subsequent clustering resulted in 13'333 unique sequences. Of these, 58.8 percent had significant similarities to known proteins, with 54.5 percent having a "best-hit" to existing Hymenoptera sequences. Comparisons with the honeybee and other insects allowed the identification of potential candidates for gene loss, pseudogene evolution, and possible incomplete annotation in the honeybee genome. Further, given the focus of much basic research and the perceived threat of disease to natural and commercial populations, the immune system of bumblebees is a particularly relevant component. Although the library is derived from unchallenged bees, we still uncover transcription of a number of immune genes spanning the principally described insect immune pathways. Additionally, the EST library provides a resource for the discovery of genetic markers that can be used in population level studies. Indeed, initial screens identified 589 simple sequence repeats and 854 potential single nucleotide polymorphisms. The resource that these B. terrestris ESTs represent is valuable for ongoing work. The ESTs provide direct evidence of transcriptionally active regions, but they will also facilitate further functional genomics, gene discovery and future genome annotation. These are important aspects in obtaining a greater

  1. Facilitating professional liaison in collaborative care for depression in UK primary care; a qualitative study utilising normalisation process theory.

    Science.gov (United States)

    Coupe, Nia; Anderson, Emma; Gask, Linda; Sykes, Paul; Richards, David A; Chew-Graham, Carolyn

    2014-05-01

    Collaborative care (CC) is an organisational framework which facilitates the delivery of a mental health intervention to patients by case managers in collaboration with more senior health professionals (supervisors and GPs), and is effective for the management of depression in primary care. However, there remains limited evidence on how to successfully implement this collaborative approach in UK primary care. This study aimed to explore to what extent CC impacts on professional working relationships, and if CC for depression could be implemented as routine in the primary care setting. This qualitative study explored perspectives of the 6 case managers (CMs), 5 supervisors (trial research team members) and 15 general practitioners (GPs) from practices participating in a randomised controlled trial of CC for depression. Interviews were transcribed verbatim and data was analysed using a two-step approach using an initial thematic analysis, and a secondary analysis using the Normalisation Process Theory concepts of coherence, cognitive participation, collective action and reflexive monitoring with respect to the implementation of CC in primary care. Supervisors and CMs demonstrated coherence in their understanding of CC, and consequently reported good levels of cognitive participation and collective action regarding delivering and supervising the intervention. GPs interviewed showed limited understanding of the CC framework, and reported limited collaboration with CMs: barriers to collaboration were identified. All participants identified the potential or experienced benefits of a collaborative approach to depression management and were able to discuss ways in which collaboration can be facilitated. Primary care professionals in this study valued the potential for collaboration, but GPs' understanding of CC and organisational barriers hindered opportunities for communication. Further work is needed to address these organisational barriers in order to facilitate

  2. Assessing the facilitators and barriers of interdisciplinary team working in primary care using normalisation process theory: An integrative review.

    Science.gov (United States)

    O'Reilly, Pauline; Lee, Siew Hwa; O'Sullivan, Madeleine; Cullen, Walter; Kennedy, Catriona; MacFarlane, Anne

    2017-01-01

    Interdisciplinary team working is of paramount importance in the reform of primary care in order to provide cost-effective and comprehensive care. However, international research shows that it is not routine practice in many healthcare jurisdictions. It is imperative to understand levers and barriers to the implementation process. This review examines interdisciplinary team working in practice, in primary care, from the perspective of service providers and analyses 1 barriers and facilitators to implementation of interdisciplinary teams in primary care and 2 the main research gaps. An integrative review following the PRISMA guidelines was conducted. Following a search of 10 international databases, 8,827 titles were screened for relevance and 49 met the criteria. Quality of evidence was appraised using predetermined criteria. Data were analysed following the principles of framework analysis using Normalisation Process Theory (NPT), which has four constructs: sense making, enrolment, enactment, and appraisal. The literature is dominated by a focus on interdisciplinary working between physicians and nurses. There is a dearth of evidence about all NPT constructs apart from enactment. Physicians play a key role in encouraging the enrolment of others in primary care team working and in enabling effective divisions of labour in the team. The experience of interdisciplinary working emerged as a lever for its implementation, particularly where communication and respect were strong between professionals. A key lever for interdisciplinary team working in primary care is to get professionals working together and to learn from each other in practice. However, the evidence base is limited as it does not reflect the experiences of all primary care professionals and it is primarily about the enactment of team working. We need to know much more about the experiences of the full network of primary care professionals regarding all aspects of implementation work. International

  3. Assessing the facilitators and barriers of interdisciplinary team working in primary care using normalisation process theory: An integrative review

    Science.gov (United States)

    O’Reilly, Pauline; Lee, Siew Hwa; O’Sullivan, Madeleine; Cullen, Walter; Kennedy, Catriona; MacFarlane, Anne

    2017-01-01

    Background Interdisciplinary team working is of paramount importance in the reform of primary care in order to provide cost-effective and comprehensive care. However, international research shows that it is not routine practice in many healthcare jurisdictions. It is imperative to understand levers and barriers to the implementation process. This review examines interdisciplinary team working in practice, in primary care, from the perspective of service providers and analyses 1 barriers and facilitators to implementation of interdisciplinary teams in primary care and 2 the main research gaps. Methods and findings An integrative review following the PRISMA guidelines was conducted. Following a search of 10 international databases, 8,827 titles were screened for relevance and 49 met the criteria. Quality of evidence was appraised using predetermined criteria. Data were analysed following the principles of framework analysis using Normalisation Process Theory (NPT), which has four constructs: sense making, enrolment, enactment, and appraisal. The literature is dominated by a focus on interdisciplinary working between physicians and nurses. There is a dearth of evidence about all NPT constructs apart from enactment. Physicians play a key role in encouraging the enrolment of others in primary care team working and in enabling effective divisions of labour in the team. The experience of interdisciplinary working emerged as a lever for its implementation, particularly where communication and respect were strong between professionals. Conclusion A key lever for interdisciplinary team working in primary care is to get professionals working together and to learn from each other in practice. However, the evidence base is limited as it does not reflect the experiences of all primary care professionals and it is primarily about the enactment of team working. We need to know much more about the experiences of the full network of primary care professionals regarding all aspects

  4. Encadrement des produits et des procédés : réglementation et normalisation du commerce international

    Directory of Open Access Journals (Sweden)

    Morin Odile

    2003-07-01

    Full Text Available Produits et procédés sont encadrés à la fois par des réglementations et, à un autre niveau, par des normes du commerce international. Cette présentation traite des textes réglementaires au niveau communautaire et national. On rappellera que l’entrée en vigueur d’un règlement européen est suivie d’une transposition dans le droit de chaque pays membre et que la réglementation nationale s’applique en l’absence de dispositions communautaires. En matière de commerce international, seront évoquées les actions de normalisation du Conseil Oléicole International (COI pour les huiles d’olive et de grignons d’olive et celles du Codex Alimentarius pour les huiles et graisses comestibles. L’ensemble des dispositions réglementaires constitue un cadre englobant les productions de l’amont vers l’aval, à la fois sur un plan vertical (oléagineux, huiles et corps gras, huiles d’olive, margarines, procédés de raffinage et transversalement (composés organiques volatils, OGM, solvants d’extraction, additifs, contaminants…. Le cas de l’huile d’olive est particulier en ce qu’il bénéficie d’un encadrement au niveau international (normes commerciales COI et Codex Alimentarius, européen et national (réglementation. Le Codex Alimentarius, quant à lui, établit des normes à caractère vertical (huiles végétales, graisses animales, huiles d’olive, matières grasses tartinables… et horizontal (additifs, résidus de pesticides…. L’essentiel de cet encadrement est résumé dans les tableaux qui illustrent cette contribution.

  5. ReadqPCR and NormqPCR: R packages for the reading, quality checking and normalisation of RT-qPCR quantification cycle (Cq data

    Directory of Open Access Journals (Sweden)

    Perkins James R

    2012-07-01

    Full Text Available Abstract Background Measuring gene transcription using real-time reverse transcription polymerase chain reaction (RT-qPCR technology is a mainstay of molecular biology. Technologies now exist to measure the abundance of many transcripts in parallel. The selection of the optimal reference gene for the normalisation of this data is a recurring problem, and several algorithms have been developed in order to solve it. So far nothing in R exists to unite these methods, together with other functions to read in and normalise the data using the chosen reference gene(s. Results We have developed two R/Bioconductor packages, ReadqPCR and NormqPCR, intended for a user with some experience with high-throughput data analysis using R, who wishes to use R to analyse RT-qPCR data. We illustrate their potential use in a workflow analysing a generic RT-qPCR experiment, and apply this to a real dataset. Packages are available from http://www.bioconductor.org/packages/release/bioc/html/ReadqPCR.htmland http://www.bioconductor.org/packages/release/bioc/html/NormqPCR.html Conclusions These packages increase the repetoire of RT-qPCR analysis tools available to the R user and allow them to (amongst other things read their data into R, hold it in an ExpressionSet compatible R object, choose appropriate reference genes, normalise the data and look for differential expression between samples.

  6. The contribution of online content to the promotion and normalisation of female genital cosmetic surgery: a systematic review of the literature.

    Science.gov (United States)

    Mowat, Hayley; McDonald, Karalyn; Dobson, Amy Shields; Fisher, Jane; Kirkman, Maggie

    2015-11-25

    Women considering female genital cosmetic surgery (FGCS) are likely to use the internet as a key source of information during the decision-making process. The aim of this systematic review was to determine what is known about the role of the internet in the promotion and normalisation of female genital cosmetic surgery and to identify areas for future research. Eight social science, medical, and communication databases and Google Scholar were searched for peer-reviewed papers published in English. Results from all papers were analysed to identify recurring and unique themes. Five papers met inclusion criteria. Three of the papers reported investigations of website content of FGCS providers, a fourth compared motivations for labiaplasty publicised on provider websites with those disclosed by women in online communities, and the fifth analysed visual depictions of female genitalia in online pornography. Analysis yielded five significant and interrelated patterns of representation, each functioning to promote and normalise the practice of FGCS: pathologisation of genital diversity; female genital appearance as important to wellbeing; characteristics of women's genitals are important for sex life; female body as degenerative and improvable through surgery; and FGCS as safe, easy, and effective. A significant gap was identified in the literature: the ways in which user-generated content might function to perpetuate, challenge, or subvert the normative discourses prevalent in online pornography and surgical websites. Further research is needed to contribute to knowledge of the role played by the internet in the promotion and normalisation of female genital cosmetic surgery.

  7. Interpreting land records

    CERN Document Server

    Wilson, Donald A

    2014-01-01

    Base retracement on solid research and historically accurate interpretation Interpreting Land Records is the industry's most complete guide to researching and understanding the historical records germane to land surveying. Coverage includes boundary retracement and the primary considerations during new boundary establishment, as well as an introduction to historical records and guidance on effective research and interpretation. This new edition includes a new chapter titled "Researching Land Records," and advice on overcoming common research problems and insight into alternative resources wh

  8. Implementing online consultations in primary care: a mixed-method evaluation extending normalisation process theory through service co-production.

    Science.gov (United States)

    Farr, Michelle; Banks, Jonathan; Edwards, Hannah B; Northstone, Kate; Bernard, Elly; Salisbury, Chris; Horwood, Jeremy

    2018-03-19

    To examine patient and staff views, experiences and acceptability of a UK primary care online consultation system and ask how the system and its implementation may be improved. Mixed-method evaluation of a primary care e-consultation system. Primary care practices in South West England. Qualitative interviews with 23 practice staff in six practices. Patient survey data for 756 e-consultations from 36 practices, with free-text survey comments from 512 patients, were analysed thematically. Anonymised patients' records were abstracted for 485 e-consultations from eight practices, including consultation types and outcomes. Descriptive statistics were used to analyse quantitative data. Analysis of implementation and the usage of the e-consultation system were informed by: (1) normalisation process theory, (2) a framework that illustrates how e-consultations were co-produced and (3) patients' and staff touchpoints. We found different expectations between patients and staff on how to use e-consultations 'appropriately'. While some patients used the system to try and save time for themselves and their general practitioners (GPs), some used e-consultations when they could not get a timely face-to-face appointment. Most e-consultations resulted in either follow-on phone (32%) or face-to-face appointments (38%) and GPs felt that this duplicated their workload. Patient satisfaction of the system was high, but a minority were dissatisfied with practice communication about their e-consultation. Where both patients and staff interact with technology, it is in effect 'co-implemented'. How patients used e-consultations impacted on practice staff's experiences and appraisal of the system. Overall, the e-consultation system studied could improve access for some patients, but in its current form, it was not perceived by practices as creating sufficient efficiencies to warrant financial investment. We illustrate how this e-consultation system and its implementation can be improved

  9. Morphology of the pancreas in type 2 diabetes: effect of weight loss with or without normalisation of insulin secretory capacity.

    Science.gov (United States)

    Al-Mrabeh, Ahmad; Hollingsworth, Kieren G; Steven, Sarah; Taylor, Roy

    2016-08-01

    This study was designed to establish whether the low volume and irregular border of the pancreas in type 2 diabetes would be normalised after reversal of diabetes. A total of 29 individuals with type 2 diabetes undertook a very low energy (very low calorie) diet for 8 weeks followed by weight maintenance for 6 months. Methods were established to quantify the pancreas volume and degree of irregularity of the pancreas border. Three-dimensional volume-rendering and fractal dimension (FD) analysis of the MRI-acquired images were employed, as was three-point Dixon imaging to quantify the fat content. There was no change in pancreas volume 6 months after reversal of diabetes compared with baseline (52.0 ± 4.9 cm(3) and 51.4 ± 4.5 cm(3), respectively; p = 0.69), nor was any volumetric change observed in the non-responders. There was an inverse relationship between the volume and fat content of the pancreas in the total study population (r =-0.50, p = 0.006). Reversal of diabetes was associated with an increase in irregularity of the pancreas borders between baseline and 8 weeks (FD 1.143 ± 0.013 and 1.169 ± 0.006, respectively; p = 0.05), followed by a decrease at 6 months (1.130 ± 0.012, p = 0.006). On the other hand, no changes in FD were seen in the non-reversed group. Restoration of normal insulin secretion did not increase the subnormal pancreas volume over 6 months in the study population. A significant change in irregularity of the pancreas borders occurred after acute weight loss only after reversal of diabetes. Pancreas morphology in type 2 diabetes may be prognostically important, and its relationship to change in beta cell function requires further study.

  10. Linguistics in Text Interpretation

    DEFF Research Database (Denmark)

    Togeby, Ole

    2011-01-01

    A model for how text interpretation proceeds from what is pronounced, through what is said to what is comunicated, and definition of the concepts 'presupposition' and 'implicature'.......A model for how text interpretation proceeds from what is pronounced, through what is said to what is comunicated, and definition of the concepts 'presupposition' and 'implicature'....

  11. MLPAinter for MLPA interpretation: an integrated approach for the analysis, visualisation and data management of Multiplex Ligation-dependent Probe Amplification

    Directory of Open Access Journals (Sweden)

    Morreau Hans

    2010-01-01

    Full Text Available Abstract Background Multiplex Ligation-Dependent Probe Amplification (MLPA is an application that can be used for the detection of multiple chromosomal aberrations in a single experiment. In one reaction, up to 50 different genomic sequences can be analysed. For a reliable work-flow, tools are needed for administrative support, data management, normalisation, visualisation, reporting and interpretation. Results Here, we developed a data management system, MLPAInter for MLPA interpretation, that is windows executable and has a stand-alone database for monitoring and interpreting the MLPA data stream that is generated from the experimental setup to analysis, quality control and visualisation. A statistical approach is applied for the normalisation and analysis of large series of MLPA traces, making use of multiple control samples and internal controls. Conclusions MLPAinter visualises MLPA data in plots with information about sample replicates, normalisation settings, and sample characteristics. This integrated approach helps in the automated handling of large series of MLPA data and guarantees a quick and streamlined dataflow from the beginning of an experiment to an authorised report.

  12. The Interpretive Function

    DEFF Research Database (Denmark)

    Agerbo, Heidi

    2017-01-01

    Approximately a decade ago, it was suggested that a new function should be added to the lexicographical function theory: the interpretive function(1). However, hardly any research has been conducted into this function, and though it was only suggested that this new function was relevant...... to incorporate into lexicographical theory, some scholars have since then assumed that this function exists(2), including the author of this contribution. In Agerbo (2016), I present arguments supporting the incorporation of the interpretive function into the function theory and suggest how non-linguistic signs...... can be treated in specific dictionary articles. However, in the current article, due to the results of recent research, I argue that the interpretive function should not be considered an individual main function. The interpretive function, contrary to some of its definitions, is not connected...

  13. Cytological artifacts masquerading interpretation

    Directory of Open Access Journals (Sweden)

    Khushboo Sahay

    2013-01-01

    Conclusions: In order to justify a cytosmear interpretation, a cytologist must be well acquainted with delayed fixation-induced cellular changes and microscopic appearances of common contaminants so as to implicate better prognosis and therapy.

  14. Schrodinger's mechanics interpretation

    CERN Document Server

    Cook, David B

    2018-01-01

    The interpretation of quantum mechanics has been in dispute for nearly a century with no sign of a resolution. Using a careful examination of the relationship between the final form of classical particle mechanics (the Hamilton–Jacobi Equation) and Schrödinger's mechanics, this book presents a coherent way of addressing the problems and paradoxes that emerge through conventional interpretations.Schrödinger's Mechanics critiques the popular way of giving physical interpretation to the various terms in perturbation theory and other technologies and places an emphasis on development of the theory and not on an axiomatic approach. When this interpretation is made, the extension of Schrödinger's mechanics in relation to other areas, including spin, relativity and fields, is investigated and new conclusions are reached.

  15. Normative interpretations of diversity

    DEFF Research Database (Denmark)

    Lægaard, Sune

    2009-01-01

    Normative interpretations of particular cases consist of normative principles or values coupled with social theoretical accounts of the empirical facts of the case. The article reviews the most prominent normative interpretations of the Muhammad cartoons controversy over the publication of drawings...... of the Prophet Muhammad in the Danish newspaper Jyllands-Posten. The controversy was seen as a case of freedom of expression, toleration, racism, (in)civility and (dis)respect, and the article notes different understandings of these principles and how the application of them to the controversy implied different...... social theoretical accounts of the case. In disagreements between different normative interpretations, appeals are often made to the ‘context', so it is also considered what roles ‘context' might play in debates over normative interpretations...

  16. Principles of radiological interpretation

    International Nuclear Information System (INIS)

    Rowe, L.J.; Yochum, T.R.

    1987-01-01

    Conventional radiographic procedures (plain film) are the most frequently utilized imaging modality in the evaluation of the skeletal system. This chapter outlines the essentials of skeletal imaging, anatomy, physiology, and interpretation

  17. Interpretable Active Learning

    OpenAIRE

    Phillips, Richard L.; Chang, Kyu Hyun; Friedler, Sorelle A.

    2017-01-01

    Active learning has long been a topic of study in machine learning. However, as increasingly complex and opaque models have become standard practice, the process of active learning, too, has become more opaque. There has been little investigation into interpreting what specific trends and patterns an active learning strategy may be exploring. This work expands on the Local Interpretable Model-agnostic Explanations framework (LIME) to provide explanations for active learning recommendations. W...

  18. Interpreter-mediated dentistry.

    Science.gov (United States)

    Bridges, Susan; Drew, Paul; Zayts, Olga; McGrath, Colman; Yiu, Cynthia K Y; Wong, H M; Au, T K F

    2015-05-01

    The global movements of healthcare professionals and patient populations have increased the complexities of medical interactions at the point of service. This study examines interpreter mediated talk in cross-cultural general dentistry in Hong Kong where assisting para-professionals, in this case bilingual or multilingual Dental Surgery Assistants (DSAs), perform the dual capabilities of clinical assistant and interpreter. An initial language use survey was conducted with Polyclinic DSAs (n = 41) using a logbook approach to provide self-report data on language use in clinics. Frequencies of mean scores using a 10-point visual analogue scale (VAS) indicated that the majority of DSAs spoke mainly Cantonese in clinics and interpreted for postgraduates and professors. Conversation Analysis (CA) examined recipient design across a corpus (n = 23) of video-recorded review consultations between non-Cantonese speaking expatriate dentists and their Cantonese L1 patients. Three patterns of mediated interpreting indicated were: dentist designated expansions; dentist initiated interpretations; and assistant initiated interpretations to both the dentist and patient. The third, rather than being perceived as negative, was found to be framed either in response to patient difficulties or within the specific task routines of general dentistry. The findings illustrate trends in dentistry towards personalized care and patient empowerment as a reaction to product delivery approaches to patient management. Implications are indicated for both treatment adherence and the education of dental professionals. Copyright © 2015 Elsevier Ltd. All rights reserved.

  19. Localized Smart-Interpretation

    Science.gov (United States)

    Lundh Gulbrandsen, Mats; Mejer Hansen, Thomas; Bach, Torben; Pallesen, Tom

    2014-05-01

    The complex task of setting up a geological model consists not only of combining available geological information into a conceptual plausible model, but also requires consistency with availably data, e.g. geophysical data. However, in many cases the direct geological information, e.g borehole samples, are very sparse, so in order to create a geological model, the geologist needs to rely on the geophysical data. The problem is however, that the amount of geophysical data in many cases are so vast that it is practically impossible to integrate all of them in the manual interpretation process. This means that a lot of the information available from the geophysical surveys are unexploited, which is a problem, due to the fact that the resulting geological model does not fulfill its full potential and hence are less trustworthy. We suggest an approach to geological modeling that 1. allow all geophysical data to be considered when building the geological model 2. is fast 3. allow quantification of geological modeling. The method is constructed to build a statistical model, f(d,m), describing the relation between what the geologists interpret, d, and what the geologist knows, m. The para- meter m reflects any available information that can be quantified, such as geophysical data, the result of a geophysical inversion, elevation maps, etc... The parameter d reflects an actual interpretation, such as for example the depth to the base of a ground water reservoir. First we infer a statistical model f(d,m), by examining sets of actual interpretations made by a geological expert, [d1, d2, ...], and the information used to perform the interpretation; [m1, m2, ...]. This makes it possible to quantify how the geological expert performs interpolation through f(d,m). As the geological expert proceeds interpreting, the number of interpreted datapoints from which the statistical model is inferred increases, and therefore the accuracy of the statistical model increases. When a model f

  20. Using normalisation process theory to understand barriers and facilitators to implementing mindfulness-based stress reduction for people with multiple sclerosis.

    Science.gov (United States)

    Simpson, Robert; Simpson, Sharon; Wood, Karen; Mercer, Stewart W; Mair, Frances S

    2018-01-01

    Objectives To study barriers and facilitators to implementation of mindfulness-based stress reduction for people with multiple sclerosis. Methods Qualitative interviews were used to explore barriers and facilitators to implementation of mindfulness-based stress reduction, including 33 people with multiple sclerosis, 6 multiple sclerosis clinicians and 2 course instructors. Normalisation process theory provided the underpinning conceptual framework. Data were analysed deductively using normalisation process theory constructs (coherence, cognitive participation, collective action and reflexive monitoring). Results Key barriers included mismatched stakeholder expectations, lack of knowledge about mindfulness-based stress reduction, high levels of comorbidity and disability and skepticism about embedding mindfulness-based stress reduction in routine multiple sclerosis care. Facilitators to implementation included introducing a pre-course orientation session; adaptations to mindfulness-based stress reduction to accommodate comorbidity and disability and participants suggested smaller, shorter classes, shortened practices, exclusion of mindful-walking and more time with peers. Post-mindfulness-based stress reduction booster sessions may be required, and objective and subjective reports of benefit would increase clinician confidence in mindfulness-based stress reduction. Discussion Multiple sclerosis patients and clinicians know little about mindfulness-based stress reduction. Mismatched expectations are a barrier to participation, as is rigid application of mindfulness-based stress reduction in the context of disability. Course adaptations in response to patient needs would facilitate uptake and utilisation. Rendering access to mindfulness-based stress reduction rapid and flexible could facilitate implementation. Embedded outcome assessment is desirable.

  1. The moral experience of illness and its impact on normalisation: Examples from narratives with Punjabi women living with rheumatoid arthritis in the UK.

    Science.gov (United States)

    Sanderson, Tessa; Calnan, Michael; Kumar, Kanta

    2015-11-01

    The moral component of living with illness has been neglected in analyses of long-term illness experiences. This article attempts to fill this gap by exploring the role of the moral experience of illness in mediating the ability of those living with a long-term condition (LTC) to normalise. This is explored through an empirical study of women of Punjabi origin living with rheumatoid arthritis (RA) in the UK. Sixteen informants were recruited through three hospitals in UK cities and interviews conducted and analysed using a grounded theory approach. The intersection between moral experience and normalisation, within the broader context of ethnic, gender and socioeconomic influences, was evident in the following: disruption of a core lived value (the centrality of family duty), beliefs about illness causation affecting informants' 'moral career', and perceived discrimination in the workplace. The data illustrate the importance of considering an ethnic community's specific values and beliefs when understanding differences in adapting to LTCs and changing identities. © 2015 Foundation for the Sociology of Health & Illness.

  2. Conjunctive interpretations of disjunctions

    Directory of Open Access Journals (Sweden)

    Robert van Rooij

    2010-09-01

    Full Text Available In this extended commentary I discuss the problem of how to account for "conjunctive" readings of some sentences with embedded disjunctions for globalist analyses of conversational implicatures. Following Franke (2010, 2009, I suggest that earlier proposals failed, because they did not take into account the interactive reasoning of what else the speaker could have said, and how else the hearer could have interpreted the (alternative sentence(s. I show how Franke's idea relates to more traditional pragmatic interpretation strategies. doi:10.3765/sp.3.11 BibTeX info

  3. Interpreting & Biomechanics. PEPNet Tipsheet

    Science.gov (United States)

    PEPNet-Northeast, 2001

    2001-01-01

    Cumulative trauma disorder (CTD) refers to a collection of disorders associated with nerves, muscles, tendons, bones, and the neurovascular (nerves and related blood vessels) system. CTD symptoms may involve the neck, back, shoulders, arms, wrists, or hands. Interpreters with CTD may experience a variety of symptoms including: pain, joint…

  4. Tokens: Facts and Interpretation.

    Science.gov (United States)

    Schmandt-Besserat, Denise

    1986-01-01

    Summarizes some of the major pieces of evidence concerning the archeological clay tokens, specifically the technique for their manufacture, their geographic distribution, chronology, and the context in which they are found. Discusses the interpretation of tokens as the first example of visible language, particularly as an antecedent of Sumerian…

  5. Life Cycle Interpretation

    DEFF Research Database (Denmark)

    Hauschild, Michael Z.; Bonou, Alexandra; Olsen, Stig Irving

    2018-01-01

    The interpretation is the final phase of an LCA where the results of the other phases are considered together and analysed in the light of the uncertainties of the applied data and the assumptions that have been made and documented throughout the study. This chapter teaches how to perform an inte...

  6. Interpretations of Greek Mythology

    NARCIS (Netherlands)

    Bremmer, Jan

    1987-01-01

    This collection of original studies offers new interpretations of some of the best known characters and themes of Greek mythology, reflecting the complexity and fascination of the Greek imagination. Following analyses of the concept of myth and the influence of the Orient on Greek mythology, the

  7. Translation, Interpreting and Lexicography

    DEFF Research Database (Denmark)

    Dam, Helle Vrønning; Tarp, Sven

    2018-01-01

    in the sense that their practice fields are typically ‘about something else’. Translators may, for example, be called upon to translate medical texts, and interpreters may be assigned to work on medical speeches. Similarly, practical lexicography may produce medical dictionaries. In this perspective, the three...

  8. Application of concentration-volume fractal method in induced polarization and resistivity data interpretation for Cu-Mo porphyry deposits exploration, case study: Nowchun Cu-Mo deposit, SE Iran

    Directory of Open Access Journals (Sweden)

    L. Daneshvar Saein

    2012-08-01

    Full Text Available The aim of this study is the utilization of the concentration-volume (C-V fractal method based on geoelectrical data including induced polarization (IP and resistivity (RS in targeting areas hosting different sulfidic mineralization zones in Nowchun Cu-Mo porphyry deposit, SE Iran. The C-V fractal model employed in this research in order to separate high and moderate sulfidic zones from low sulfidic zone and barren wall rocks in the deposit is corresponding to chargeability and resistivity. Results obtained from the C-V method indicate that there is a positive correlation between subsurface mineralization and sulfide mineralized zones; additionally, use of the C-V method based on geophysical data is recognized as an accurate approach for delineation of various mineralization zones in the depth for optimization of mineral exploration operation, particularly in porphyry deposits.

  9. Does normalisation improve the diagnostic performance of apparent diffusion coefficient values for prostate cancer assessment? A blinded independent-observer evaluation

    International Nuclear Information System (INIS)

    Rosenkrantz, A.B.; Khalef, V.; Xu, W.; Babb, J.S.; Taneja, S.S.; Doshi, A.M.

    2015-01-01

    Aim: To evaluate the performance of normalised apparent diffusion coefficient (ADC) values for prostate cancer assessment when performed by independent observers blinded to histopathology findings. Materials and methods: Fifty-eight patients undergoing 3 T phased-array coil magnetic resonance imaging (MRI) including diffusion-weighted imaging (DWI; maximal b-value 1000 s/mm 2 ) before prostatectomy were included. Two radiologists independently evaluated the images, unaware of the histopathology findings. Regions of interest (ROIs) were drawn within areas showing visually low ADC within the peripheral zone (PZ) and transition zone (TZ) bilaterally. ROIs were also placed within regions in both lobes not suspicious for tumour, allowing computation of normalised ADC (nADC) ratios between suspicious and non-suspicious regions. The diagnostic performance of ADC and nADC were compared. Results: For PZ tumour detection, ADC achieved significantly higher area under the receiver operating characteristic curve (AUC; p=0.026) and specificity (p=0.021) than nADC for reader 1, and significantly higher AUC (p=0.025) than nADC for reader 2. For TZ tumour detection, nADC achieved significantly higher specificity (p=0.003) and accuracy (p=0.004) than ADC for reader 2. For PZ Gleason score >3+3 tumour detection, ADC achieved significantly higher AUC (p=0.003) and specificity (p=0.005) than nADC for reader 1, and significantly higher AUC (p=0.023) than nADC for reader 2. For TZ Gleason score >3+3 tumour detection, ADC achieved significantly higher specificity (p=0.019) than nADC for reader 1. Conclusion: In contrast to prior studies performing unblinded evaluations, ADC was observed to outperform nADC overall for two independent observers blinded to the histopathology findings. Therefore, although strategies to improve the utility of ADC measurements in prostate cancer assessment merit continued investigation, caution is warranted when applying normalisation to improve diagnostic

  10. Selection of reference genes for normalisation of real-time RT-PCR in brain-stem death injury in Ovis aries

    Directory of Open Access Journals (Sweden)

    Fraser John F

    2009-07-01

    Full Text Available Abstract Background Heart and lung transplantation is frequently the only therapeutic option for patients with end stage cardio respiratory disease. Organ donation post brain stem death (BSD is a pre-requisite, yet BSD itself causes such severe damage that many organs offered for donation are unusable, with lung being the organ most affected by BSD. In Australia and New Zealand, less than 50% of lungs offered for donation post BSD are suitable for transplantation, as compared with over 90% of kidneys, resulting in patients dying for lack of suitable lungs. Our group has developed a novel 24 h sheep BSD model to mimic the physiological milieu of the typical human organ donor. Characterisation of the gene expression changes associated with BSD is critical and will assist in determining the aetiology of lung damage post BSD. Real-time PCR is a highly sensitive method involving multiple steps from extraction to processing RNA so the choice of housekeeping genes is important in obtaining reliable results. Little information however, is available on the expression stability of reference genes in the sheep pulmonary artery and lung. We aimed to establish a set of stably expressed reference genes for use as a standard for analysis of gene expression changes in BSD. Results We evaluated the expression stability of 6 candidate normalisation genes (ACTB, GAPDH, HGPRT, PGK1, PPIA and RPLP0 using real time quantitative PCR. There was a wide range of Ct-values within each tissue for pulmonary artery (15–24 and lung (16–25 but the expression pattern for each gene was similar across the two tissues. After geNorm analysis, ACTB and PPIA were shown to be the most stably expressed in the pulmonary artery and ACTB and PGK1 in the lung tissue of BSD sheep. Conclusion Accurate normalisation is critical in obtaining reliable and reproducible results in gene expression studies. This study demonstrates tissue associated variability in the selection of these

  11. Personal literary interpretation

    Directory of Open Access Journals (Sweden)

    Michał Januszkiewicz

    2015-11-01

    Full Text Available The article titled “Personal literary interpretation” deals with problems which have usually been marginalized in literary studies, but which seem to be very important in the context of the humanities, as broadly defined. The author of this article intends to rethink the problem of literary studies not in objective, but in personal terms. This is why the author wants to talk about what he calls personal literary interpretation, which has nothing to do with subjective or irrational thinking, but which is rather grounded in the hermeneutical rule that says that one must believe in order tounderstand a text or the other (where ‘believe’ also means: ‘to love’, ‘engage’, and ‘be open’. The article presents different determinants of this attitude, ranging from Dilthey to Heidegger and Gadamer. Finally, the author subscribes to the theory of personal interpretation, which is always dialogical.

  12. Interpretation and clinical applications

    International Nuclear Information System (INIS)

    Higgins, C.B.

    1987-01-01

    This chapter discusses the factors to be kept in mind during routine interpretation of MR images. This includes the factors that determine contrast on standard spin-echo images and some distinguishing features between true lesions and artifactually simulated lesions. This chapter also indicates the standard protocols for MRI of various portions of the body. Finally, the current indications for MRI of various portions of the body are suggested; however, it is recognized that the indications for MRI are rapidly increasing and consequently, at the time of publication of this chapter, it is likely that many more applications will have become evident. Interpretation of magnetic resonance (MR) images requires consideration of anatomy and tissue characteristics and extraction of artifacts resulting from motion and other factors

  13. The Age of Interpretation

    OpenAIRE

    Gianni Vattimo

    2013-01-01

    Gianni Vattimo, who is both a Catholic and a frequent critic of the Church, explores the surprising congruence between Christianity and hermeneutics in light of the dissolution of metaphysical truth. As in hermeneutics, Vatimo claims, interpretation is central to Christianity. Influenced by hermeneutics and borrowing largely from the Nietzschean and Heideggerian heritage, the Italian philosopher, who has been instrumental in promoting a nihilistic approach to Christianity, draws here on Nietz...

  14. From playfulness and self-centredness via grand expectations to normalisation: a psychoanalytical rereading of the history of molecular genetics.

    Science.gov (United States)

    Zwart, H A E

    2013-11-01

    In this paper, I will reread the history of molecular genetics from a psychoanalytical angle, analysing it as a case history. Building on the developmental theories of Freud and his followers, I will distinguish four stages, namely: (1) oedipal childhood, notably the epoch of model building (1943-1953); (2) the latency period, with a focus on the development of basic skills (1953-1989); (3) adolescence, exemplified by the Human Genome Project, with its fierce conflicts, great expectations and grandiose claims (1989-2003) and (4) adulthood (2003-present) during which revolutionary research areas such as molecular biology and genomics have achieved a certain level of normalcy--have evolved into a normal science. I will indicate how a psychoanalytical assessment conducted in this manner may help us to interpret and address some of the key normative issues that have been raised with regard to molecular genetics over the years, such as 'relevance', 'responsible innovation' and 'promise management'.

  15. The Age of Interpretation

    Directory of Open Access Journals (Sweden)

    Gianni Vattimo

    2013-01-01

    Full Text Available Gianni Vattimo, who is both a Catholic and a frequent critic of the Church, explores the surprising congruence between Christianity and hermeneutics in light of the dissolution of metaphysical truth. As in hermeneutics, Vatimo claims, interpretation is central to Christianity. Influenced by hermeneutics and borrowing largely from the Nietzschean and Heideggerian heritage, the Italian philosopher, who has been instrumental in promoting a nihilistic approach to Christianity, draws here on Nietzsche’s writings on nihilism, which is not to be understood in a purely negative sense. Vattimo suggests that nihilism not only expands the Christian message of charity, but also transforms it into its endless human potential. In “The Age of Interpretation,” the author shows that hermeneutical radicalism “reduces all reality to message,” so that the opposition between facts and norms turns out to be misguided, for both are governed by the interpretative paradigms through which someone (always a concrete, historically situated someone makes sense of them. Vattimo rejects some of the deplorable political consequences of hermeneutics and claims that traditional hermeneutics is in collusion with various political-ideological neutralizations.

  16. Long-term performance of grid-connected photovoltaic plant - Appendix 2: normalised monthly statistics; Langzeitverhalten von netzgekoppelten Photovoltaikanlagen 2 (LZPV2). Anhang 2: Normierte Monatsstatistiken

    Energy Technology Data Exchange (ETDEWEB)

    Renken, C.; Haeberlin, H.

    2003-07-01

    This is the third part of a four-part final report for the Swiss Federal Office of Energy (SFOE) made by the University of Applied Sciences in Burgdorf, Switzerland. This report presents the findings of a project begun in 1992 that monitored the performance of around 40 photovoltaic (PV) installations in Switzerland. This extensive second appendix to the report describes the eight installations that were monitored in detail, including - amongst others - the demonstration installations on Mont Soleil in the Jura mountains and on the Jungfraujoch in the Alps as well as three test installations using modern thin-film technologies in Burgdorf. The normalised monthly specific performance of these installations was monitored. The report presents the various performance figures in graphical form.

  17. Attention training normalises combat-related post-traumatic stress disorder effects on emotional Stroop performance using lexically matched word lists.

    Science.gov (United States)

    Khanna, Maya M; Badura-Brack, Amy S; McDermott, Timothy J; Shepherd, Alex; Heinrichs-Graham, Elizabeth; Pine, Daniel S; Bar-Haim, Yair; Wilson, Tony W

    2015-08-26

    We examined two groups of combat veterans, one with post-traumatic stress disorder (PTSD) (n = 27) and another without PTSD (n = 16), using an emotional Stroop task (EST) with word lists matched across a series of lexical variables (e.g. length, frequency, neighbourhood size, etc.). Participants with PTSD exhibited a strong EST effect (longer colour-naming latencies for combat-relevant words as compared to neutral words). Veterans without PTSD produced no such effect, t  .37. Participants with PTSD then completed eight sessions of attention training (Attention Control Training or Attention Bias Modification Training) with a dot-probe task utilising threatening and neutral faces. After training, participants-especially those undergoing Attention Control Training-no longer produced longer colour-naming latencies for combat-related words as compared to other words, indicating normalised attention allocation processes after treatment.

  18. The economic costs of natural disasters globally from 1900-2015: historical and normalised floods, storms, earthquakes, volcanoes, bushfires, drought and other disasters

    Science.gov (United States)

    Daniell, James; Wenzel, Friedemann; Schaefer, Andreas

    2016-04-01

    For the first time, a breakdown of natural disaster losses from 1900-2015 based on over 30,000 event economic losses globally is given based on increased analysis within the CATDAT Damaging Natural Disaster databases. Using country-CPI and GDP deflator adjustments, over 7 trillion (2015-adjusted) in losses have occurred; over 40% due to flood/rainfall, 26% due to earthquake, 19% due to storm effects, 12% due to drought, 2% due to wildfire and under 1% due to volcano. Using construction cost indices, higher percentages of flood losses are seen. Depending on how the adjustment of dollars are made to 2015 terms (CPI vs. construction cost indices), between 6.5 and 14.0 trillion USD (2015-adjusted) of natural disaster losses have been seen from 1900-2015 globally. Significant reductions in economic losses have been seen in China and Japan from 1950 onwards. An AAL of around 200 billion in the last 16 years has been seen equating to around 0.25% of Global GDP or around 0.1% of Net Capital Stock per year. Normalised losses have also been calculated to examine the trends in vulnerability through time for economic losses. The normalisation methodology globally using the exposure databases within CATDAT that were undertaken previously in papers for the earthquake and volcano databases, are used for this study. The original event year losses are adjusted directly by capital stock change, very high losses are observed with respect to floods over time (however with improved flood control structures). This shows clear trends in the improvement of building stock towards natural disasters and a decreasing trend in most perils for most countries.

  19. The applicability of normalisation process theory to speech and language therapy: a review of qualitative research on a speech and language intervention.

    Science.gov (United States)

    James, Deborah M

    2011-08-12

    The Bercow review found a high level of public dissatisfaction with speech and language services for children. Children with speech, language, and communication needs (SLCN) often have chronic complex conditions that require provision from health, education, and community services. Speech and language therapists are a small group of Allied Health Professionals with a specialist skill-set that equips them to work with children with SLCN. They work within and across the diverse range of public service providers. The aim of this review was to explore the applicability of Normalisation Process Theory (NPT) to the case of speech and language therapy. A review of qualitative research on a successfully embedded speech and language therapy intervention was undertaken to test the applicability of NPT. The review focused on two of the collective action elements of NPT (relational integration and interaction workability) using all previously published qualitative data from both parents and practitioners' perspectives on the intervention. The synthesis of the data based on the Normalisation Process Model (NPM) uncovered strengths in the interpersonal processes between the practitioners and parents, and weaknesses in how the accountability of the intervention is distributed in the health system. The analysis based on the NPM uncovered interpersonal processes between the practitioners and parents that were likely to have given rise to successful implementation of the intervention. In previous qualitative research on this intervention where the Medical Research Council's guidance on developing a design for a complex intervention had been used as a framework, the interpersonal work within the intervention had emerged as a barrier to implementation of the intervention. It is suggested that the design of services for children and families needs to extend beyond the consideration of benefits and barriers to embrace the social processes that appear to afford success in embedding

  20. Identifying Stable Reference Genes for qRT-PCR Normalisation in Gene Expression Studies of Narrow-Leafed Lupin (Lupinus angustifolius L..

    Directory of Open Access Journals (Sweden)

    Candy M Taylor

    Full Text Available Quantitative Reverse Transcription PCR (qRT-PCR is currently one of the most popular, high-throughput and sensitive technologies available for quantifying gene expression. Its accurate application depends heavily upon normalisation of gene-of-interest data with reference genes that are uniformly expressed under experimental conditions. The aim of this study was to provide the first validation of reference genes for Lupinus angustifolius (narrow-leafed lupin, a significant grain legume crop using a selection of seven genes previously trialed as reference genes for the model legume, Medicago truncatula. In a preliminary evaluation, the seven candidate reference genes were assessed on the basis of primer specificity for their respective targeted region, PCR amplification efficiency, and ability to discriminate between cDNA and gDNA. Following this assessment, expression of the three most promising candidates [Ubiquitin C (UBC, Helicase (HEL, and Polypyrimidine tract-binding protein (PTB] was evaluated using the NormFinder and RefFinder statistical algorithms in two narrow-leafed lupin lines, both with and without vernalisation treatment, and across seven organ types (cotyledons, stem, leaves, shoot apical meristem, flowers, pods and roots encompassing three developmental stages. UBC was consistently identified as the most stable candidate and has sufficiently uniform expression that it may be used as a sole reference gene under the experimental conditions tested here. However, as organ type and developmental stage were associated with greater variability in relative expression, it is recommended using UBC and HEL as a pair to achieve optimal normalisation. These results highlight the importance of rigorously assessing candidate reference genes for each species across a diverse range of organs and developmental stages. With emerging technologies, such as RNAseq, and the completion of valuable transcriptome data sets, it is possible that other

  1. Interpretation of Internet technology

    DEFF Research Database (Denmark)

    Madsen, Charlotte Øland

    2001-01-01

    Research scope: The topic of the research project is to investigate how new internet technologies such as e-trade and customer relation marketing and management are implemented in Danish food processing companies. The aim is to use Weick's (1995) sensemaking concept to analyse the strategic...... processes leading to the use of internet marketing technologies and to investigate how these new technologies are interpreted into the organisation. Investigating the organisational socio-cognitive processes underlying the decision making processes will give further insight into the socio...

  2. Changing interpretations of Plotinus

    DEFF Research Database (Denmark)

    Catana, Leo

    2013-01-01

    about method point in other directions. Eduard Zeller (active in the second half of the 19th century) is typically regarded as the first who gave a satisfying account of Plotinus’ philosophy as a whole. In this article, on the other hand, Zeller is seen as the one who finalised a tradition initiated...... in the 18th century. Very few Plotinus scholars have examined the interpretative development prior to Zeller. Schiavone (1952) and Bonetti (1971), for instance, have given little attention to Brucker’s introduction of the concept system of philosophy. The present analysis, then, has value...

  3. Physical interpretation of antigravity

    Science.gov (United States)

    Bars, Itzhak; James, Albin

    2016-02-01

    Geodesic incompleteness is a problem in both general relativity and string theory. The Weyl-invariant Standard Model coupled to general relativity (SM +GR ), and a similar treatment of string theory, are improved theories that are geodesically complete. A notable prediction of this approach is that there must be antigravity regions of spacetime connected to gravity regions through gravitational singularities such as those that occur in black holes and cosmological bang/crunch. Antigravity regions introduce apparent problems of ghosts that raise several questions of physical interpretation. It was shown that unitarity is not violated, but there may be an instability associated with negative kinetic energies in the antigravity regions. In this paper we show that the apparent problems can be resolved with the interpretation of the theory from the perspective of observers strictly in the gravity region. Such observers cannot experience the negative kinetic energy in antigravity directly, but can only detect in and out signals that interact with the antigravity region. This is no different from a spacetime black box for which the information about its interior is encoded in scattering amplitudes for in/out states at its exterior. Through examples we show that negative kinetic energy in antigravity presents no problems of principles but is an interesting topic for physical investigations of fundamental significance.

  4. An application of Extended Normalisation Process Theory in a randomised controlled trial of a complex social intervention: Process evaluation of the Strengthening Families Programme (10–14 in Wales, UK

    Directory of Open Access Journals (Sweden)

    Jeremy Segrott

    2017-12-01

    Conclusions: Extended Normalisation Process Theory provided a useful framework for assessing implementation and explaining variation by examining intervention-context interactions. Findings highlight the need for process evaluations to consider both the structural and process components of implementation to explain whether programme activities are delivered as intended and why.

  5. Biblical Interpretation Beyond Historicity

    DEFF Research Database (Denmark)

    Biblical Interpretation beyond Historicity evaluates the new perspectives that have emerged since the crisis over historicity in the 1970s and 80s in the field of biblical scholarship. Several new studies in the field, as well as the ‘deconstructive’ side of literary criticism that emerged from...... writers such as Derrida and Wittgenstein, among others, lead biblical scholars today to view the texts of the Bible more as literary narratives than as sources for a history of Israel. Increased interest in archaeological and anthropological studies in writing the history of Palestine and the ancient Near...... and the commitment to a new approach to both the history of Palestine and the Bible’s place in ancient history. This volume features essays from a range of highly regarded scholars, and is divided into three sections: “Beyond Historicity”, which explores alternative historical roles for the Bible, “Greek Connections...

  6. Interpretation of galaxy counts

    International Nuclear Information System (INIS)

    Tinsely, B.M.

    1980-01-01

    New models are presented for the interpretation of recent counts of galaxies to 24th magnitude, and predictions are shown to 28th magnitude for future comparison with data from the Space Telescope. The results supersede earlier, more schematic models by the author. Tyson and Jarvis found in their counts a ''local'' density enhancement at 17th magnitude, on comparison with the earlier models; the excess is no longer significant when a more realistic mixture of galaxy colors is used. Bruzual and Kron's conclusion that Kron's counts show evidence for evolution at faint magnitudes is confirmed, and it is predicted that some 23d magnitude galaxies have redshifts greater than unity. These may include spheroidal systems, elliptical galaxies, and the bulges of early-type spirals and S0's, seen during their primeval rapid star formation

  7. Innovative Procedure for fhe, In Situ, Measurement of the Resistive Thermal Coefficient Of H(D)/Pd During Electrolysis; Cross-Comparison of New Elements Detected in The Th–Hg–Pd–D(H) Electrolytic Cells

    CERN Document Server

    Celani, F; Righi, E; Trenta, G; Catena, C; D’Agostaro, G; Quercia, P; Andreassi, V; Marini, P; Di Stefano, V; Nakamura, M; Mancini, A; Sona, P G; Fontana, F; Gamberale, L; Garbelli, D; Celia, E; Falcioni, F; Marchesini, M; Novaro, E; Mastromatteo, U

    2005-01-01

    In the framework of cold fusion studies one of the most important parameters is the deuterium (D) to palladium (Pd) ratio, D/Pd. It is well known that the value of this parameter is related to the normalised resistivity (R/R0) of the D–Pd system. When at high D/Pd ratios (i.e. at low R/R0 values) some excess heat occurs, the Pd wire temperature increase and, as a consequence, the apparent R/R0 value also increases. This effect might give raise to ambiguous data interpretation: similar results are in fact expected in case of a Pd wire degassing (i.e. decreasing of D/Pd ratio). To solve this problem, we developed an innovative procedure and a suitable experimental set-up for the in situ measurement of the Resistive Temperature Coefficient (which is affected only by the real D/Pd ratio) during electrolysis. We will report the results on the hydrogen and deuterium loading of thin (50 µm), and long (60 cm) Pd wires, immersed in a solution of C2H5OD (or C2H5OH) and D2O (or H2O), with addition of thorium (Th) a...

  8. Scanning Tunneling Microscopy - image interpretation

    International Nuclear Information System (INIS)

    Maca, F.

    1998-01-01

    The basic ideas of image interpretation in Scanning Tunneling Microscopy are presented using simple quantum-mechanical models and supplied with examples of successful application. The importance is stressed of a correct interpretation of this brilliant experimental surface technique

  9. Critical Assessment of Metagenome Interpretation

    DEFF Research Database (Denmark)

    Sczyrba, Alexander; Hofmann, Peter; Belmann, Peter

    2017-01-01

    Methods for assembly, taxonomic profiling and binning are key to interpreting metagenome data, but a lack of consensus about benchmarking complicates performance assessment. The Critical Assessment of Metagenome Interpretation (CAMI) challenge has engaged the global developer community to benchma...

  10. The interpretation of administrative contracts

    Directory of Open Access Journals (Sweden)

    Cătălin-Silviu SĂRARU

    2014-06-01

    Full Text Available The article analyzes the principles of interpretation for administrative contracts, in French law and in Romanian law. In the article are highlighted derogations from the rules of contract interpretation in common law. Are examined the exceptions to the principle of good faith, the principle of common intention (willingness of the parties, the principle of good administration, the principle of extensive interpretation of the administrative contract. The article highlights the importance and role of the interpretation in administrative contracts.

  11. Interpretation of computed tomographic images

    International Nuclear Information System (INIS)

    Stickle, R.L.; Hathcock, J.T.

    1993-01-01

    This article discusses the production of optimal CT images in small animal patients as well as principles of radiographic interpretation. Technical factors affecting image quality and aiding image interpretation are included. Specific considerations for scanning various anatomic areas are given, including indications and potential pitfalls. Principles of radiographic interpretation are discussed. Selected patient images are illustrated

  12. Global Earthquake and Volcanic Eruption Economic losses and costs from 1900-2014: 115 years of the CATDAT database - Trends, Normalisation and Visualisation

    Science.gov (United States)

    Daniell, James; Skapski, Jens-Udo; Vervaeck, Armand; Wenzel, Friedemann; Schaefer, Andreas

    2015-04-01

    Over the past 12 years, an in-depth database has been constructed for socio-economic losses from earthquakes and volcanoes. The effects of earthquakes and volcanic eruptions have been documented in many databases, however, many errors and incorrect details are often encountered. To combat this, the database was formed with socioeconomic checks of GDP, capital stock, population and other elements, as well as providing upper and lower bounds to each available event loss. The definition of economic losses within the CATDAT Damaging Earthquakes Database (Daniell et al., 2011a) as of v6.1 has now been redefined to provide three options of natural disaster loss pricing, including reconstruction cost, replacement cost and actual loss, in order to better define the impact of historical disasters. Similarly for volcanoes as for earthquakes, a reassessment has been undertaken looking at the historical net and gross capital stock and GDP at the time of the event, including the depreciated stock, in order to calculate the actual loss. A normalisation has then been undertaken using updated population, GDP and capital stock. The difference between depreciated and gross capital can be removed from the historical loss estimates which have been all calculated without taking depreciation of the building stock into account. The culmination of time series from 1900-2014 of net and gross capital stock, GDP, direct economic loss data, use of detailed studies of infrastructure age, and existing damage surveys, has allowed the first estimate of this nature. The death tolls in earthquakes from 1900-2014 are presented in various forms, showing around 2.32 million deaths due to earthquakes (with a range of 2.18 to 2.63 million) and around 59% due to masonry buildings and 28% from secondary effects. For the death tolls from the volcanic eruption database, 98000 deaths with a range from around 83000 to 107000 is seen from 1900-2014. The application of VSL life costing from death and injury

  13. Metodología basada en redes neurales para interpretación de la resistividad del suelo en zonas urbanas. Methodology based on neural networks for earth resistivity interpretation in congested urban areas

    Directory of Open Access Journals (Sweden)

    Miguel Martínez Lozano

    2015-04-01

    Full Text Available Uno de los problemas que se afronta durante el diseño de un sistema de puesta a tierra (PAT en zonas urbanas, es la obtención de los parámetros eléctricos del suelo, ya que los métodos tradicionales de medición de resistividad no se pueden aplicar por problemas de espacio. En este trabajo, se plantea una alternativa para la obtención de la resistividad, mediante sondeo eléctrico introduciendo una barra vertical y registrando cómo varía la resistencia de PAT del electrodo en función de la profundidad; con esos resultados se desarrolla una metodología basada en redes neurales, para estimar los parámetros del suelo para un modelo biestratificado del mismo. Se estudia por tanto, el tema de las complicaciones de medición en zonas urbanas y se plantea en detalle la metodología empleando técnicas modernas de medición y procesamiento. Los resultados obtenidos, tanto en fase de simulación digital como con ensayos de campo, muestran la validez.  One of the main troubles for grounding system design in an electrical installation on congested urban areas is obtaining the soil parameters, since the traditional measurements techniques are not applicable due to the limited space. In the present work, an alternative procedure based on introducing a driven rod into the soil and registering the variation of ground resistance versus the depth, is presented; with the field measurements obtained, a procedure were evaluated to estimate the soil parameters in a simplified bi-stratified model (two vertical layers using a trained neural network to minimize the effort and time to obtain the respective results. The trouble about the measurement and estimation of electrical soil properties in congested urban areas is solved with the detailed methodology presented, based on non conventional measurement techniques and computational processing. The results obtained during both digital simulation and field measurements, demonstrates the validity of the

  14. Symmorphosis through dietary regulation: a combinatorial role for proteolysis, autophagy and protein synthesis in normalising muscle metabolism and function of hypertrophic mice after acute starvation.

    Directory of Open Access Journals (Sweden)

    Henry Collins-Hooper

    Full Text Available Animals are imbued with adaptive mechanisms spanning from the tissue/organ to the cellular scale which insure that processes of homeostasis are preserved in the landscape of size change. However we and others have postulated that the degree of adaptation is limited and that once outside the normal levels of size fluctuations, cells and tissues function in an aberant manner. In this study we examine the function of muscle in the myostatin null mouse which is an excellent model for hypertrophy beyond levels of normal growth and consequeces of acute starvation to restore mass. We show that muscle growth is sustained through protein synthesis driven by Serum/Glucocorticoid Kinase 1 (SGK1 rather than Akt1. Furthermore our metabonomic profiling of hypertrophic muscle shows that carbon from nutrient sources is being channelled for the production of biomass rather than ATP production. However the muscle displays elevated levels of autophagy and decreased levels of muscle tension. We demonstrate the myostatin null muscle is acutely sensitive to changes in diet and activates both the proteolytic and autophagy programmes and shutting down protein synthesis more extensively than is the case for wild-types. Poignantly we show that acute starvation which is detrimental to wild-type animals is beneficial in terms of metabolism and muscle function in the myostatin null mice by normalising tension production.

  15. Understanding clinician attitudes towards implementation of guided self-help cognitive behaviour therapy for those who hear distressing voices: using factor analysis to test normalisation process theory.

    Science.gov (United States)

    Hazell, Cassie M; Strauss, Clara; Hayward, Mark; Cavanagh, Kate

    2017-07-24

    The Normalisation Process Theory (NPT) has been used to understand the implementation of physical health care interventions. The current study aims to apply the NPT model to a secondary mental health context, and test the model using exploratory factor analysis. This study will consider the implementation of a brief cognitive behaviour therapy for psychosis (CBTp) intervention. Mental health clinicians were asked to complete a NPT-based questionnaire on the implementation of a brief CBTp intervention. All clinicians had experience of either working with the target client group or were able to deliver psychological therapies. In total, 201 clinicians completed the questionnaire. The results of the exploratory factor analysis found partial support for the NPT model, as three of the NPT factors were extracted: (1) coherence, (2) cognitive participation, and (3) reflexive monitoring. We did not find support for the fourth NPT factor (collective action). All scales showed strong internal consistency. Secondary analysis of these factors showed clinicians to generally support the implementation of the brief CBTp intervention. This study provides strong evidence for the validity of the three NPT factors extracted. Further research is needed to determine whether participants' level of seniority moderates factor extraction, whether this factor structure can be generalised to other healthcare settings, and whether pre-implementation attitudes predict actual implementation outcomes.

  16. Assessment of the efficacy of a novel tailored vitamin K dosing regimen in lowering the International Normalised Ratio in over-anticoagulated patients: a randomised clinical trial.

    Science.gov (United States)

    Kampouraki, Emmanouela; Avery, Peter J; Wynne, Hilary; Biss, Tina; Hanley, John; Talks, Kate; Kamali, Farhad

    2017-09-01

    Current guidelines advocate using fixed-doses of oral vitamin K to reverse excessive anticoagulation in warfarinised patients who are either asymptomatic or have minor bleeds. Over-anticoagulated patients present with a wide range of International Normalised Ratio (INR) values and response to fixed doses of vitamin K varies. Consequently a significant proportion of patients remain outside their target INR after vitamin K administration, making them prone to either haemorrhage or thromboembolism. We compared the performance of a novel tailored vitamin K dosing regimen to that of a fixed-dose regimen with the primary measure being the proportion of over-anticoagulated patients returning to their target INR within 24 h. One hundred and eighty-one patients with an index INR > 6·0 (asymptomatic or with minor bleeding) were randomly allocated to receive oral administration of either a tailored dose (based upon index INR and body surface area) or a fixed-dose (1 or 2 mg) of vitamin K. A greater proportion of patients treated with the tailored dose returned to within target INR range compared to the fixed-dose regimen (68·9% vs. 52·8%; P = 0·026), whilst a smaller proportion of patients remained above target INR range (12·2% vs. 34·0%; P vitamin K dosing is more accurate than fixed-dose regimen in lowering INR to within target range in excessively anticoagulated patients. © 2017 John Wiley & Sons Ltd.

  17. Popular cinema and lesbian interpretive strategies.

    Science.gov (United States)

    Dobinson, C; Young, K

    2000-01-01

    In its examination of the relationship between popular film and lesbian viewing practices, this study attempts to more fully elucidate current ideas around audience engagement and forms of cultural reception. Drawing on 15 in-depth interviews conducted in Western Canada in 1996, the results clearly demonstrate the existence of active lesbian viewers, whose interpretations of popular film are intimately informed by lesbian-specific life experiences and cultural competencies. Although the social conditions which create the need for resistant viewing are themselves oppressive, subversion of mainstream film holds out some possibility of empowerment for lesbian viewers.

  18. Orientalismi: nuove prospettive interpretative

    Directory of Open Access Journals (Sweden)

    Gabriele Proglio

    2012-11-01

    Full Text Available This paper is aimed at reconsidering the concept of Orientalism in a new and multiple perspective, and at proposing a different interpretation of the relationship between culture and power, starting from Edward Said’s theoretical frame of reference. If Said’s representational model is repositioned out of structuralist and foucaultian frameworks and separated from the gramscian idea of hegemony-subordination, indeed, it may be possible to re-discuss the traditional profile identifying the Other in the European cultures. My basic assumption here is that Orientalism should not be understood as a consensus mechanism, which is able to produce diversified images of the Orient and the Oriental on demand. Although, of course, in most cases Orientalism is connected to the issue of power, its meanings could also be explained —as it will be soon shown— otherwise. Let’s take The Invisible Cities by Italo Calvino as an example. Here the narratives are not just multiple repetitions of Venice —in Said’s case, the same would hold for Europeanism—, but they could be strategically re-appropriated by those “others” and “alterities” whose bodies and identities are imposed by the Eurocentric discourse. In this sense, a double link may be identified with queer theories and postcolonial studies, and the notion of subordination will be rethought. Finally, from the above mentioned borders, a new idea of image emerges, which appears as linear, uniform and flattened only to the European gaze, whereas in actual fact it is made of imaginaries and forms of knowledge, which combine representation with the conceptualization of power relationships.

  19. Working memory and simultaneous interpreting

    OpenAIRE

    Timarova, Sarka

    2009-01-01

    Working memory is a cognitive construct underlying a number of abilities, and it has been hypothesised for many years that it is crucial for interpreting. A number of studies have been conducted with the aim to support this hypothesis, but research has not yielded convincing results. Most researchers focused on studying working memory differences between interpreters and non-interpreters with the rationale that differences in working memory between the two groups would provide evidence of wor...

  20. Automated, computer interpreted radioimmunoassay results

    International Nuclear Information System (INIS)

    Hill, J.C.; Nagle, C.E.; Dworkin, H.J.; Fink-Bennett, D.; Freitas, J.E.; Wetzel, R.; Sawyer, N.; Ferry, D.; Hershberger, D.

    1984-01-01

    90,000 Radioimmunoassay results have been interpreted and transcribed automatically using software developed for use on a Hewlett Packard Model 1000 mini-computer system with conventional dot matrix printers. The computer program correlates the results of a combination of assays, interprets them and prints a report ready for physician review and signature within minutes of completion of the assay. The authors designed and wrote a computer program to query their patient data base for radioassay laboratory results and to produce a computer generated interpretation of these results using an algorithm that produces normal and abnormal interpretives. Their laboratory assays 50,000 patient samples each year using 28 different radioassays. Of these 85% have been interpreted using our computer program. Allowances are made for drug and patient history and individualized reports are generated with regard to the patients age and sex. Finalization of reports is still subject to change by the nuclear physician at the time of final review. Automated, computerized interpretations have realized cost savings through reduced personnel and personnel time and provided uniformity of the interpretations among the five physicians. Prior to computerization of interpretations, all radioassay results had to be dictated and reviewed for signing by one of the resident or staff physicians. Turn around times for reports prior to the automated computer program generally were two to three days. Whereas, the computerized interpret system allows reports to generally be issued the day assays are completed

  1. Clinical, immunological and treatment-related factors associated with normalised CD4+/CD8+ T-cell ratio: effect of naïve and memory T-cell subsets.

    LENUS (Irish Health Repository)

    Tinago, Willard

    2014-01-01

    Although effective antiretroviral therapy(ART) increases CD4+ T-cell count, responses to ART vary considerably and only a minority of patients normalise their CD4+\\/CD8+ ratio. Although retention of naïve CD4+ T-cells is thought to predict better immune responses, relationships between CD4+ and CD8+ T-cell subsets and CD4+\\/CD8+ ratio have not been well described.

  2. A formative evaluation of the implementation of a medication safety data collection tool in English healthcare settings: A qualitative interview study using normalisation process theory.

    Science.gov (United States)

    Rostami, Paryaneh; Ashcroft, Darren M; Tully, Mary P

    2018-01-01

    Reducing medication-related harm is a global priority; however, impetus for improvement is impeded as routine medication safety data are seldom available. Therefore, the Medication Safety Thermometer was developed within England's National Health Service. This study aimed to explore the implementation of the tool into routine practice from users' perspectives. Fifteen semi-structured interviews were conducted with purposely sampled National Health Service staff from primary and secondary care settings. Interview data were analysed using an initial thematic analysis, and subsequent analysis using Normalisation Process Theory. Secondary care staff understood that the Medication Safety Thermometer's purpose was to measure medication safety and improvement. However, other uses were reported, such as pinpointing poor practice. Confusion about its purpose existed in primary care, despite further training, suggesting unsuitability of the tool. Decreased engagement was displayed by staff less involved with medication use, who displayed less ownership. Nonetheless, these advocates often lacked support from management and frontline levels, leading to an overall lack of engagement. Many participants reported efforts to drive scale-up of the use of the tool, for example, by securing funding, despite uncertainty around how to use data. Successful improvement was often at ward-level and went unrecognised within the wider organisation. There was mixed feedback regarding the value of the tool, often due to a perceived lack of "capacity". However, participants demonstrated interest in learning how to use their data and unexpected applications of data were reported. Routine medication safety data collection is complex, but achievable and facilitates improvements. However, collected data must be analysed, understood and used for further work to achieve improvement, which often does not happen. The national roll-out of the tool has accelerated shared learning; however, a number of

  3. Repeated lysergic acid diethylamide in an animal model of depression: Normalisation of learning behaviour and hippocampal serotonin 5-HT2 signalling.

    Science.gov (United States)

    Buchborn, Tobias; Schröder, Helmut; Höllt, Volker; Grecksch, Gisela

    2014-06-01

    A re-balance of postsynaptic serotonin (5-HT) receptor signalling, with an increase in 5-HT1A and a decrease in 5-HT2A signalling, is a final common pathway multiple antidepressants share. Given that the 5-HT1A/2A agonist lysergic acid diethylamide (LSD), when repeatedly applied, selectively downregulates 5-HT2A, but not 5-HT1A receptors, one might expect LSD to similarly re-balance the postsynaptic 5-HT signalling. Challenging this idea, we use an animal model of depression specifically responding to repeated antidepressant treatment (olfactory bulbectomy), and test the antidepressant-like properties of repeated LSD treatment (0.13 mg/kg/d, 11 d). In line with former findings, we observe that bulbectomised rats show marked deficits in active avoidance learning. These deficits, similarly as we earlier noted with imipramine, are largely reversed by repeated LSD administration. Additionally, bulbectomised rats exhibit distinct anomalies of monoamine receptor signalling in hippocampus and/or frontal cortex; from these, only the hippocampal decrease in 5-HT2 related [(35)S]-GTP-gamma-S binding is normalised by LSD. Importantly, the sham-operated rats do not profit from LSD, and exhibit reduced hippocampal 5-HT2 signalling. As behavioural deficits after bulbectomy respond to agents classified as antidepressants only, we conclude that the effect of LSD in this model can be considered antidepressant-like, and discuss it in terms of a re-balance of hippocampal 5-HT2/5-HT1A signalling. © The Author(s) 2014.

  4. A formative evaluation of the implementation of a medication safety data collection tool in English healthcare settings: A qualitative interview study using normalisation process theory.

    Directory of Open Access Journals (Sweden)

    Paryaneh Rostami

    Full Text Available Reducing medication-related harm is a global priority; however, impetus for improvement is impeded as routine medication safety data are seldom available. Therefore, the Medication Safety Thermometer was developed within England's National Health Service. This study aimed to explore the implementation of the tool into routine practice from users' perspectives.Fifteen semi-structured interviews were conducted with purposely sampled National Health Service staff from primary and secondary care settings. Interview data were analysed using an initial thematic analysis, and subsequent analysis using Normalisation Process Theory.Secondary care staff understood that the Medication Safety Thermometer's purpose was to measure medication safety and improvement. However, other uses were reported, such as pinpointing poor practice. Confusion about its purpose existed in primary care, despite further training, suggesting unsuitability of the tool. Decreased engagement was displayed by staff less involved with medication use, who displayed less ownership. Nonetheless, these advocates often lacked support from management and frontline levels, leading to an overall lack of engagement. Many participants reported efforts to drive scale-up of the use of the tool, for example, by securing funding, despite uncertainty around how to use data. Successful improvement was often at ward-level and went unrecognised within the wider organisation. There was mixed feedback regarding the value of the tool, often due to a perceived lack of "capacity". However, participants demonstrated interest in learning how to use their data and unexpected applications of data were reported.Routine medication safety data collection is complex, but achievable and facilitates improvements. However, collected data must be analysed, understood and used for further work to achieve improvement, which often does not happen. The national roll-out of the tool has accelerated shared learning; however

  5. Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes

    DEFF Research Database (Denmark)

    Højberg, P V; Vilsbøll, T; Rabøl, R

    2008-01-01

    of near-normalisation of the blood glucose level could improve insulin responses to GIP and GLP-1 in patients with type 2 diabetes. METHODS: Eight obese patients with type 2 diabetes with poor glycaemic control (HbA(1c) 8.6 +/- 1.3%), were investigated before and after 4 weeks of near......-normalisation of blood glucose (mean blood glucose 7.4 +/- 1.2 mmol/l) using insulin treatment. Before and after insulin treatment the participants underwent three hyperglycaemic clamps (15 mmol/l) with infusion of GLP-1, GIP or saline. Insulin responses were evaluated as the incremental area under the plasma C......-peptide curve. RESULTS: Before and after near-normalisation of blood glucose, the C-peptide responses did not differ during the early phase of insulin secretion (0-10 min). The late phase C-peptide response (10-120 min) increased during GIP infusion from 33.0 +/- 8.5 to 103.9 +/- 24.2 (nmol/l) x (110 min)(-1...

  6. Symmetric normalisation for intuitionistic logic

    DEFF Research Database (Denmark)

    Guenot, Nicolas; Straßburger, Lutz

    2014-01-01

    We present two proof systems for implication-only intuitionistic logic in the calculus of structures. The first is a direct adaptation of the standard sequent calculus to the deep inference setting, and we describe a procedure for cut elimination, similar to the one from the sequent calculus......, but using a non-local rewriting. The second system is the symmetric completion of the first, as normally given in deep inference for logics with a DeMorgan duality: all inference rules have duals, as cut is dual to the identity axiom. We prove a generalisation of cut elimination, that we call symmetric...

  7. Forced normalisation precipitated by lamotrigine.

    Science.gov (United States)

    Clemens, Béla

    2005-10-01

    To report two patients with lamotrigine-induced forced normalization (FN). Evaluation of the patient files, EEG, and video-EEG records, with special reference to the parallel clinical and EEG changes before, during, and after FN. This is the first documented report of lamotrigine-induced FN. The two epileptic patients (one of them was a 10-year-old girl) were successfully treated with lamotrigine. Their seizures ceased and interictal epileptiform events disappeared from the EEG record. Simultaneously, the patients displayed de novo occurrence of psychopathologic manifestations and disturbed behaviour. Reduction of the daily dose of LTG led to disappearance of the psychopathological symptoms and reappearance of the spikes but not the seizures. Lamotrigine may precipitate FN in adults and children. Analysis of the cases showed that lamotrigine-induced FN is a dose-dependent phenomenon and can be treated by reduction of the daily dose of the drug.

  8. Tax Treaty Interpretation in Spain

    OpenAIRE

    Soler Roch, María Teresa; Ribes Ribes, Aurora

    2001-01-01

    This paper provides insight in the interpretation of Spanish double taxation conventions. Taking as a premise the Vienna Convention on the Law of Treaties and the wording of Article 3(2) OECD Model Convention, the authors explore the relevance of mutual agreements, tax authority practice and foreign court decisions on the tax treaty interpretation.

  9. Pragmatics in Court Interpreting: Additions

    DEFF Research Database (Denmark)

    Jacobsen, Bente

    2003-01-01

    Danish court interpreters are expected to follow ethical guidelines, which instruct them to deliver exact verbatim versions of source texts. However, this requirement often clashes with the reality of the interpreting situation in the courtroom. This paper presents and discusses the findings of a...

  10. Intercultural pragmatics and court interpreting

    DEFF Research Database (Denmark)

    Jacobsen, Bente

    2008-01-01

      This paper reports on an on-going investigation of conversational implicature in triadic speech events: Interpreter-mediated questionings in criminal proceedings in Danish district courts. The languages involved are Danish and English, and the mode of interpreting is the consecutive mode. The c...

  11. Interpreting Recoil for Undergraduate Students

    Science.gov (United States)

    Elsayed, Tarek A.

    2012-01-01

    The phenomenon of recoil is usually explained to students in the context of Newton's third law. Typically, when a projectile is fired, the recoil of the launch mechanism is interpreted as a reaction to the ejection of the smaller projectile. The same phenomenon is also interpreted in the context of the conservation of linear momentum, which is…

  12. Do Interpreters Indeed Have Superior Working Memory in Interpreting

    Institute of Scientific and Technical Information of China (English)

    于飞

    2012-01-01

    With the frequent communications between China and western countries in the field of economy,politics and culture,etc,Inter preting becomes more and more important to people in all walks of life.This paper aims to testify the author’s hypothesis "professional interpreters have similar short-term memory with unprofessional interpreters,but they have superior working memory." After the illustration of literatures concerning with consecutive interpreting,short-term memory and working memory,experiments are designed and analysis are described.

  13. Abstract Interpretation and Attribute Gramars

    DEFF Research Database (Denmark)

    Rosendahl, Mads

    The objective of this thesis is to explore the connections between abstract interpretation and attribute grammars as frameworks in program analysis. Abstract interpretation is a semantics-based program analysis method. A large class of data flow analysis problems can be expressed as non-standard ...... is presented in the thesis. Methods from abstract interpretation can also be used in correctness proofs of attribute grammars. This proof technique introduces a new class of attribute grammars based on domain theory. This method is illustrated with examples....

  14. Andries van Aarde's Matthew Interpretation

    African Journals Online (AJOL)

    Test

    2011-01-14

    Jan 14, 2011 ... Secondly, it is an individual and independent interpretation of the Matthean .... specific social context is emphasised: certain events in the early church ...... Moses-theology, a Covenant-theology or any other exclusive theology.

  15. Dialectica Interpretation with Marked Counterexamples

    Directory of Open Access Journals (Sweden)

    Trifon Trifonov

    2011-01-01

    Full Text Available Goedel's functional "Dialectica" interpretation can be used to extract functional programs from non-constructive proofs in arithmetic by employing two sorts of higher-order witnessing terms: positive realisers and negative counterexamples. In the original interpretation decidability of atoms is required to compute the correct counterexample from a set of candidates. When combined with recursion, this choice needs to be made for every step in the extracted program, however, in some special cases the decision on negative witnesses can be calculated only once. We present a variant of the interpretation in which the time complexity of extracted programs can be improved by marking the chosen witness and thus avoiding recomputation. The achieved effect is similar to using an abortive control operator to interpret computational content of non-constructive principles.

  16. Federal Aviation Administration Legal Interpretations

    Data.gov (United States)

    Department of Transportation — Legal Interpretations and the Chief Counsel's opinions are now available at this site. Your may choose to search by year or by text search. Please note that not all...

  17. Interpreting Sustainability for Urban Forests

    Directory of Open Access Journals (Sweden)

    Camilo Ordóñez

    2010-06-01

    Full Text Available Incisive interpretations of urban-forest sustainability are important in furthering our understanding of how to sustain the myriad values associated with urban forests. Our analysis of earlier interpretations reveals conceptual gaps. These interpretations are attached to restrictive definitions of a sustainable urban forest and limited to a rather mechanical view of maintaining the biophysical structure of trees. The probing of three conceptual domains (urban forest concepts, sustainable development, and sustainable forest management leads to a broader interpretation of urban-forest sustainability as the process of sustaining urban forest values through time and across space. We propose that values—and not services, benefits, functions or goods—is a superior concept to refer to what is to be sustained in and by an urban forest.

  18. Tarague Interpretive Trail Mitigation Plan

    National Research Council Canada - National Science Library

    Welch, David

    2001-01-01

    ...), International Archaeological Research Institute, Inc. (lARfI) has prepared a mitigation plan for development of an interpretive trail at Tarague Beach, located on the north coast of the island of Guam (Fig. 1...

  19. Begriffsverwirrung? Interpretation Analyse Bedeutung Applikation

    Directory of Open Access Journals (Sweden)

    Mayr, Jeremia Josef M.

    2017-11-01

    Full Text Available Empirical research on the reception of biblical texts confronts scientific exegesis with valid and challenging requests and demands. The hermeneutic question of the compatibility of interpretations resulting out of different contexts (e.g. scientific exegesis and ordinary readers‘ exegesis plays an important role. Taking these requests seriously by coherently restructuring fundamental and central aspects of the theory of scientific interpretation, the present article attempts to offer a stimulating approach for further investigation.

  20. Court interpreting and pragmatic meaning

    DEFF Research Database (Denmark)

    Jacobsen, Bente

    In Denmark, court interpreters are required to deliver verbatim translations of speakers' originals and to refrain from transferring pragmatic meaning. Yet, as this paper demonstrates, pragmatic meaning is central to courtroom interaction.......In Denmark, court interpreters are required to deliver verbatim translations of speakers' originals and to refrain from transferring pragmatic meaning. Yet, as this paper demonstrates, pragmatic meaning is central to courtroom interaction....

  1. Interpretation of macroscopic quantum phenomena

    International Nuclear Information System (INIS)

    Baumann, K.

    1986-01-01

    It is argued that a quantum theory without observer is required for the interpretation of macroscopic quantum tunnelling. Such a theory is obtained by augmenting QED by the actual electric field in the rest system of the universe. An equation of the motion of this field is formulated form which the correct macroscopic behavior of the universe and the validity of the Born interpretation is derived. Care is taken to use mathematically sound concepts only. (Author)

  2. Supporting the use of theory in cross-country health services research: a participatory qualitative approach using Normalisation Process Theory as an example.

    Science.gov (United States)

    O'Donnell, Catherine A; Mair, Frances S; Dowrick, Christopher; Brún, Mary O'Reilly-de; Brún, Tomas de; Burns, Nicola; Lionis, Christos; Saridaki, Aristoula; Papadakaki, Maria; Muijsenbergh, Maria van den; Weel-Baumgarten, Evelyn van; Gravenhorst, Katja; Cooper, Lucy; Princz, Christine; Teunissen, Erik; Mareeuw, Francine van den Driessen; Vlahadi, Maria; Spiegel, Wolfgang; MacFarlane, Anne

    2017-08-21

    To describe and reflect on the process of designing and delivering a training programme supporting the use of theory, in this case Normalisation Process Theory (NPT), in a multisite cross-country health services research study. Participatory research approach using qualitative methods. Six European primary care settings involving research teams from Austria, England, Greece, Ireland, The Netherlands and Scotland. RESTORE research team consisting of 8 project applicants, all senior primary care academics, and 10 researchers. Professional backgrounds included general practitioners/family doctors, social/cultural anthropologists, sociologists and health services/primary care researchers. Views of all research team members (n=18) were assessed using qualitative evaluation methods, analysed qualitatively by the trainers after each session. Most of the team had no experience of using NPT and many had not applied theory to prospective, qualitative research projects. Early training proved didactic and overloaded participants with information. Drawing on RESTORE's methodological approach of Participatory Learning and Action, workshops using role play, experiential interactive exercises and light-hearted examples not directly related to the study subject matter were developed. Evaluation showed the study team quickly grew in knowledge and confidence in applying theory to fieldwork.Recommendations applicable to other studies include: accepting that theory application is not a linear process, that time is needed to address researcher concerns with the process, and that experiential, interactive learning is a key device in building conceptual and practical knowledge. An unanticipated benefit was the smooth transition to cross-country qualitative coding of study data. A structured programme of training enhanced and supported the prospective application of a theory, NPT, to our work but raised challenges. These were not unique to NPT but could arise with the application of any

  3. Interpreter services in emergency medicine.

    Science.gov (United States)

    Chan, Yu-Feng; Alagappan, Kumar; Rella, Joseph; Bentley, Suzanne; Soto-Greene, Marie; Martin, Marcus

    2010-02-01

    Emergency physicians are routinely confronted with problems associated with language barriers. It is important for emergency health care providers and the health system to strive for cultural competency when communicating with members of an increasingly diverse society. Possible solutions that can be implemented include appropriate staffing, use of new technology, and efforts to develop new kinds of ties to the community served. Linguistically specific solutions include professional interpretation, telephone interpretation, the use of multilingual staff members, the use of ad hoc interpreters, and, more recently, the use of mobile computer technology at the bedside. Each of these methods carries a specific set of advantages and disadvantages. Although professionally trained medical interpreters offer improved communication, improved patient satisfaction, and overall cost savings, they are often underutilized due to their perceived inefficiency and the inconclusive results of their effect on patient care outcomes. Ultimately, the best solution for each emergency department will vary depending on the population served and available resources. Access to the multiple interpretation options outlined above and solid support and commitment from hospital institutions are necessary to provide proper and culturally competent care for patients. Appropriate communications inclusive of interpreter services are essential for culturally and linguistically competent provider/health systems and overall improved patient care and satisfaction. Copyright (c) 2010 Elsevier Inc. All rights reserved.

  4. The impact of working memory on interpreting

    Institute of Scientific and Technical Information of China (English)

    白云安; 张国梅

    2016-01-01

    This paper investigates the roles of working memory in interpreting process. First of all, it gives a brief introduction to interpreting. Secondly, the paper exemplifies the role of working memory in interpreting. The result reveals that the working memory capacity of interpreters is not adsolutely proportional to the quality of interpreting in the real interpreting conditions. The performance of an interpreter with well-equipped working memory capacity will comprehensively influenced by various elements.

  5. Default Sarcastic Interpretations: On the Priority of Nonsalient Interpretations

    Science.gov (United States)

    Giora, Rachel; Drucker, Ari; Fein, Ofer; Mendelson, Itamar

    2015-01-01

    Findings from five experiments support the view that negation generates sarcastic utterance-interpretations by default. When presented in isolation, novel negative constructions ("Punctuality is not his forte," "Thoroughness is not her most distinctive feature"), free of semantic anomaly or internal incongruity, were…

  6. The Interpretive Approach to Religious Education: Challenging Thompson's Interpretation

    Science.gov (United States)

    Jackson, Robert

    2012-01-01

    In a recent book chapter, Matthew Thompson makes some criticisms of my work, including the interpretive approach to religious education and the research and activity of Warwick Religions and Education Research Unit. Against the background of a discussion of religious education in the public sphere, my response challenges Thompson's account,…

  7. Interpretation and evaluation of radiograph

    International Nuclear Information System (INIS)

    Abdul Nassir Ibrahim; Azali Muhammad; Ab. Razak Hamzah; Abd. Aziz Mohamed; Mohamad Pauzi Ismail

    2008-01-01

    After digestion, the interpreter must interpreted and evaluate the image on film, usually many radiograph stuck in this step, if there is good density, so there are no problem. This is a final stage of radiography work and this work must be done by level two or three radiographer. This is a final stages before the radiographer give a result to their customer for further action. The good interpreter must know what kind of artifact, is this artifact are dangerous or not and others. In this chapter, the entire artifact that usually showed will be discussed briefly with the good illustration and picture to make the reader understand and know the type of artifact that exists.

  8. Interpretation and digestion of radiograph

    International Nuclear Information System (INIS)

    Abdul Nassir Ibrahim; Azali Muhammad; Ab. Razak Hamzah; Abd. Aziz Mohamed; Mohamad Pauzi Ismail

    2008-01-01

    Radiography digestion is final test for the radiography to make sure that radiograph produced will inspect their quality of the image before its interpreted. This level is critical level where if there is a mistake, all of the radiography work done before will be unaccepted. So as mention earlier, it can waste time, cost and more worst it can make the production must shut down. So, this step, level two radiographers or interpreter must evaluate the radiograph carefully. For this purpose, digestion room and densitometer must used. Of course all the procedure must follow the specification that mentioned in document. There are several needs must fill before we can say the radiograph is corrected or not like the location of penetrameter, number of penetrameter that showed, the degree of density of film, and usually there is no problem in this step and the radiograph can go to interpretation and evaluation step as will mentioned in next chapter.

  9. Image analysis enhancement and interpretation

    International Nuclear Information System (INIS)

    Glauert, A.M.

    1978-01-01

    The necessary practical and mathematical background are provided for the analysis of an electron microscope image in order to extract the maximum amount of structural information. Instrumental methods of image enhancement are described, including the use of the energy-selecting electron microscope and the scanning transmission electron microscope. The problems of image interpretation are considered with particular reference to the limitations imposed by radiation damage and specimen thickness. A brief survey is given of the methods for producing a three-dimensional structure from a series of two-dimensional projections, although emphasis is really given on the analysis, processing and interpretation of the two-dimensional projection of a structure. (Auth.)

  10. Interpretative challenges in face analysis

    DEFF Research Database (Denmark)

    de Oliveira, Sandi Michele; Hernández-Flores, Nieves

    2015-01-01

    In current research on face analysis questions of who and what should be interpreted, as well as how, are of central interest. In English language research, this question has led to a debate on the concepts of P1 (laypersons, representing the “emic” perspective) and P2 (researchers, representing...... in Spanish and address forms in European Portuguese, we view P1 and P2 as being far more complex than the literature suggests, with subgroups (different types of laypersons and researchers, respectively). At the micro-level we will describe the roles each subgroup plays in the interpretative process...

  11. Methods for interpreting lists of affected genes obtained in a DNA microarray experiment

    Directory of Open Access Journals (Sweden)

    Hedegaard Jakob

    2009-07-01

    Full Text Available Abstract Background The aim of this paper was to describe and compare the methods used and the results obtained by the participants in a joint EADGENE (European Animal Disease Genomic Network of Excellence and SABRE (Cutting Edge Genomics for Sustainable Animal Breeding workshop focusing on post analysis of microarray data. The participating groups were provided with identical lists of microarray probes, including test statistics for three different contrasts, and the normalised log-ratios for each array, to be used as the starting point for interpreting the affected probes. The data originated from a microarray experiment conducted to study the host reactions in broilers occurring shortly after a secondary challenge with either a homologous or heterologous species of Eimeria. Results Several conceptually different analytical approaches, using both commercial and public available software, were applied by the participating groups. The following tools were used: Ingenuity Pathway Analysis, MAPPFinder, LIMMA, GOstats, GOEAST, GOTM, Globaltest, TopGO, ArrayUnlock, Pathway Studio, GIST and AnnotationDbi. The main focus of the approaches was to utilise the relation between probes/genes and their gene ontology and pathways to interpret the affected probes/genes. The lack of a well-annotated chicken genome did though limit the possibilities to fully explore the tools. The main results from these analyses showed that the biological interpretation is highly dependent on the statistical method used but that some common biological conclusions could be reached. Conclusion It is highly recommended to test different analytical methods on the same data set and compare the results to obtain a reliable biological interpretation of the affected genes in a DNA microarray experiment.

  12. Analyzing and Interpreting Historical Sources

    DEFF Research Database (Denmark)

    Kipping, Matthias; Wadhwani, Dan; Bucheli, Marcelo

    2014-01-01

    This chapter outlines a methodology for the interpretation of historical sources, helping to realize their full potential for the study of organization, while overcoming their challenges in terms of distortions created by time, changes in context, and selective production or preservation. Drawing....... The chapter contributes to the creation of a language for describing the use of historical sources in management research....

  13. Quantum theory needs no 'Interpretation'

    International Nuclear Information System (INIS)

    Fuchs, Christopher A.; Peres, Asher

    2000-01-01

    Purpose of this article is to stress the fact that Quantum Theory does not need an interpretation other than being an algorithm for computing probabilities associated with macroscopic phenomena and measurements. It does not ''describ'' reality, and the wave function is not objective entity, it only gives the evolution of our probabilities for the outcomes potential experiments. (AIP) (c)

  14. An Authentic Interpretation of Laws

    Directory of Open Access Journals (Sweden)

    Teodor Antić

    2015-01-01

    Full Text Available Authentic interpretation of laws is a legal institute whereby a legislator gives the authentic meaning to a specific legal norm in case of its incorrect or diversified interpretation in practice. It has the same legal force as the law. Retroactivity and influence on pending cases are its inherent characteristics. Due to these characteristics and their relation to the principles of the rule of law, legal certainty and separation of powers, it is subjected to severe criticism not only by legal theory but also legal practice. The author analyses the institute of authentic interpretation from historical and comparative point of view and through the Croatian normative regulation, practice of the Croatian Parliament and academic debate, including opinions in favour as well as against it. On these grounds the author concludes that higher quality of law making procedure could make the authentic interpretation dispensable. On the other hand, should this institute be kept in the legal order it is essential to receive more effective constitutional control.

  15. Copenhagen interpretation versus Bohm's theory

    International Nuclear Information System (INIS)

    Baumann, K.

    1985-01-01

    The objections raised against Bohm's interpretation of quantum theory are reexamined, and arguments are presented in favour of this theory. Bohm's QED is modified such as to include Dirac particles. It is pointed out that the electric field may be chosen as the 'actual' field instead of the magnetic field. Finally, the theory is reformulated in terms of an arbitrary actual field. (Author)

  16. Interpretation of Recurrent Neural Networks

    DEFF Research Database (Denmark)

    Pedersen, Morten With; Larsen, Jan

    1997-01-01

    This paper addresses techniques for interpretation and characterization of trained recurrent nets for time series problems. In particular, we focus on assessment of effective memory and suggest an operational definition of memory. Further we discuss the evaluation of learning curves. Various nume...

  17. An interpretation of signature inversion

    International Nuclear Information System (INIS)

    Onishi, Naoki; Tajima, Naoki

    1988-01-01

    An interpretation in terms of the cranking model is presented to explain why signature inversion occurs for positive γ of the axially asymmetric deformation parameter and emerges into specific orbitals. By introducing a continuous variable, the eigenvalue equation can be reduced to a one dimensional Schroedinger equation by means of which one can easily understand the cause of signature inversion. (author)

  18. Abstract Interpretation of Mobile Ambients

    DEFF Research Database (Denmark)

    Hansen, René Rydhof; Jensen, J. G.; Nielson, Flemming

    1999-01-01

    We demonstrate that abstract interpretation is useful for analysing calculi of computation such as the ambient calculus (which is based on the p-calculus); more importantly, we show that the entire development can be expressed in a constraint-based formalism that is becoming exceedingly popular...

  19. Interpretive Reproduction in Children's Play

    Science.gov (United States)

    Corsaro, William A.

    2012-01-01

    The author looks at children's play from the perspective of interpretive reproduction, emphasizing the way children create their own unique peer cultures, which he defines as a set of routines, artifacts, values, and concerns that children engage in with their playmates. The article focuses on two types of routines in the peer culture of preschool…

  20. Interpreting Data: The Hybrid Mind

    Science.gov (United States)

    Heisterkamp, Kimberly; Talanquer, Vicente

    2015-01-01

    The central goal of this study was to characterize major patterns of reasoning exhibited by college chemistry students when analyzing and interpreting chemical data. Using a case study approach, we investigated how a representative student used chemical models to explain patterns in the data based on structure-property relationships. Our results…

  1. Interpretable functional principal component analysis.

    Science.gov (United States)

    Lin, Zhenhua; Wang, Liangliang; Cao, Jiguo

    2016-09-01

    Functional principal component analysis (FPCA) is a popular approach to explore major sources of variation in a sample of random curves. These major sources of variation are represented by functional principal components (FPCs). The intervals where the values of FPCs are significant are interpreted as where sample curves have major variations. However, these intervals are often hard for naïve users to identify, because of the vague definition of "significant values". In this article, we develop a novel penalty-based method to derive FPCs that are only nonzero precisely in the intervals where the values of FPCs are significant, whence the derived FPCs possess better interpretability than the FPCs derived from existing methods. To compute the proposed FPCs, we devise an efficient algorithm based on projection deflation techniques. We show that the proposed interpretable FPCs are strongly consistent and asymptotically normal under mild conditions. Simulation studies confirm that with a competitive performance in explaining variations of sample curves, the proposed FPCs are more interpretable than the traditional counterparts. This advantage is demonstrated by analyzing two real datasets, namely, electroencephalography data and Canadian weather data. © 2015, The International Biometric Society.

  2. Interpretation and the Aesthetic Dimension

    Science.gov (United States)

    Mortensen, Charles O.

    1976-01-01

    The author, utilizing a synthesis of philosophic comments on aesthetics, provides a discourse on the aesthetic dimension and offers examples of how interpreters can nurture the innate sense of beauty in man. Poetic forms, such as haiku, are used to relate the aesthetic relationship between man and the environment. (BT)

  3. Abstract Interpretation Using Attribute Grammar

    DEFF Research Database (Denmark)

    Rosendahl, Mads

    1990-01-01

    This paper deals with the correctness proofs of attribute grammars using methods from abstract interpretation. The technique will be described by defining a live-variable analysis for a small flow-chart language and proving it correct with respect to a continuation style semantics. The proof...

  4. Current voltage characteristics of composite superconductors with high contact resistance

    International Nuclear Information System (INIS)

    Akhmetov, A.A.; Baev, V.P.

    1984-01-01

    An experimental study has been made of current-voltage characteristics of composite superconductors with contact resistance between superconducting filaments and normal metal with high electrical conductivity. It is shown that stable resistive states exist in such conductors over a wide range of currents. The presence of resistive states is interpreted in terms of the resistive domain concept. The minimum and maximum currents of resistive states are found to be dependent on the electrical resistance of normal metal and magnetic field. (author)

  5. Federal Motor Vehicle Safety Standards Interpretations

    Data.gov (United States)

    Department of Transportation — NHTSA's Chief Counsel interprets the statutes that the agency administers and the regulations that it promulgates. The Chief Counsel's interpretations, issued in the...

  6. Directionality effects in simultaneous language interpreting: the case of sign language interpreters in The Netherlands.

    Science.gov (United States)

    Van Dijk, Rick; Boers, Eveline; Christoffels, Ingrid; Hermans, Daan

    2011-01-01

    The quality of interpretations produced by sign language interpreters was investigated. Twenty-five experienced interpreters were instructed to interpret narratives from (a) spoken Dutch to Sign Language of The Netherlands (SLN), (b) spoken Dutch to Sign Supported Dutch (SSD), and (c) SLN to spoken Dutch. The quality of the interpreted narratives was assessed by 5 certified sign language interpreters who did not participate in the study. Two measures were used to assess interpreting quality: the propositional accuracy of the interpreters' interpretations and a subjective quality measure. The results showed that the interpreted narratives in the SLN-to-Dutch interpreting direction were of lower quality (on both measures) than the interpreted narratives in the Dutch-to-SLN and Dutch-to-SSD directions. Furthermore, interpreters who had begun acquiring SLN when they entered the interpreter training program performed as well in all 3 interpreting directions as interpreters who had acquired SLN from birth.

  7. Visual perception and radiographic interpretation

    International Nuclear Information System (INIS)

    Papageorges, M.

    1998-01-01

    Although interpretation errors are common in radiology, their causes are still debated. Perceptual mechanisms appear to be responsible for a large proportion of mistakes made by both neophytes and trained radiologists. Erroneous perception of familiar contours can be triggered by unrelated opacities. Conversely, visual information cannot induce a specific perception if the observer is not familiar with the concept represented or its radiographicappearance. Additionally, the area of acute vision is smaller than is commonly recognized. Other factors, such as the attitude, beliefs,.: preconceptions, and expectations of the viewer, can affect what he or she ''sees'' whenviewing any object, including a radiograph. Familiarity with perceptual mechanisms and the limitations of the visual system as well as multiple readings may be necessary to reduce interpretation errors

  8. Modeling and interpretation of images*

    Directory of Open Access Journals (Sweden)

    Min Michiel

    2015-01-01

    Full Text Available Imaging protoplanetary disks is a challenging but rewarding task. It is challenging because of the glare of the central star outshining the weak signal from the disk at shorter wavelengths and because of the limited spatial resolution at longer wavelengths. It is rewarding because it contains a wealth of information on the structure of the disks and can (directly probe things like gaps and spiral structure. Because it is so challenging, telescopes are often pushed to their limitations to get a signal. Proper interpretation of these images therefore requires intimate knowledge of the instrumentation, the detection method, and the image processing steps. In this chapter I will give some examples and stress some issues that are important when interpreting images from protoplanetary disks.

  9. Design of interpretable fuzzy systems

    CERN Document Server

    Cpałka, Krzysztof

    2017-01-01

    This book shows that the term “interpretability” goes far beyond the concept of readability of a fuzzy set and fuzzy rules. It focuses on novel and precise operators of aggregation, inference, and defuzzification leading to flexible Mamdani-type and logical-type systems that can achieve the required accuracy using a less complex rule base. The individual chapters describe various aspects of interpretability, including appropriate selection of the structure of a fuzzy system, focusing on improving the interpretability of fuzzy systems designed using both gradient-learning and evolutionary algorithms. It also demonstrates how to eliminate various system components, such as inputs, rules and fuzzy sets, whose reduction does not adversely affect system accuracy. It illustrates the performance of the developed algorithms and methods with commonly used benchmarks. The book provides valuable tools for possible applications in many fields including expert systems, automatic control and robotics.

  10. Quantum mechanics interpretation: scalled debate

    International Nuclear Information System (INIS)

    Sanchez Gomez, J. L.

    2000-01-01

    This paper discusses the two main issues of the so called quantum debate, that started in 1927 with the famous Bohr-Einstein controversy; namely non-separability and the projection postulate. Relevant interpretations and formulations of quantum mechanics are critically analyzed in the light of the said issues. The treatment is focused chiefly on fundamental points, so that technical ones are practically not dealt with here. (Author) 20 refs

  11. Topological interpretation of Luttinger theorem

    OpenAIRE

    Seki, Kazuhiro; Yunoki, Seiji

    2017-01-01

    Based solely on the analytical properties of the single-particle Green's function of fermions at finite temperatures, we show that the generalized Luttinger theorem inherently possesses topological aspects. The topological interpretation of the generalized Luttinger theorem can be introduced because i) the Luttinger volume is represented as the winding number of the single-particle Green's function and thus ii) the deviation of the theorem, expressed with a ratio between the interacting and n...

  12. Operational interpretations of quantum discord

    International Nuclear Information System (INIS)

    Cavalcanti, D.; Modi, K.; Aolita, L.; Boixo, S.; Piani, M.; Winter, A.

    2011-01-01

    Quantum discord quantifies nonclassical correlations beyond the standard classification of quantum states into entangled and unentangled. Although it has received considerable attention, it still lacks any precise interpretation in terms of some protocol in which quantum features are relevant. Here we give quantum discord its first information-theoretic operational meaning in terms of entanglement consumption in an extended quantum-state-merging protocol. We further relate the asymmetry of quantum discord with the performance imbalance in quantum state merging and dense coding.

  13. Defunctionalized Interpreters for Programming Languages

    DEFF Research Database (Denmark)

    Danvy, Olivier

    2008-01-01

    by Reynolds in ``Definitional Interpreters for Higher-Order Programming Languages'' for functional implementations of denotational semantics, natural semantics, and big-step abstract machines using closure conversion, CPS transformation, and defunctionalization. Over the last few years, the author and his...... operational semantics can be expressed as a reduction semantics: for deterministic languages, a reduction semantics is a structural operational semantics in continuation style, where the reduction context is a defunctionalized continuation. As the defunctionalized counterpart of the continuation of a one...

  14. A Generator for Composition Interpreters

    DEFF Research Database (Denmark)

    Steensgaard-Madsen, Jørgen

    1997-01-01

    programming language design, specification and implementation then apply. A component can be considered as defining objects or commands according to convenience. A description language including type information provides sufficient means to describe component interaction according to the underlying abstract......Composition of program components must be expressed in some language, and late composition can be achieved by an interpreter for the composition language. A suitable notion of component is obtained by identifying it with the semantics of a generalised structured command. Experiences from...

  15. Interpreting radiographs. 4. The carpus

    International Nuclear Information System (INIS)

    Burguez, P.N.

    1984-01-01

    The complexity of the carpus which has three major joints, seven or eight carpal bones and five adjacent bones, each of which articulates with one or more of the carpal elements, necessitates good quality radiographs for definitive radiographic interpretation may be extremely difficult because of the disparity between radiographic changes and obvious clinical signs and, therefore, must be discussed in the light of a thorough clinical assessment

  16. Paris convention - Decisions, recommendations, interpretations

    International Nuclear Information System (INIS)

    1990-01-01

    This booklet is published in a single edition in English and French. It contains decisions, recommendations and interpretations concerning the 1960 Paris Convention on Third Party Liability in the Field of Nuclear Energy adopted by the OECD Steering Committee and the OECD Council. All the instruments are set out according to the Article of the Convention to which they relate and explanatory notes are added where necessary [fr

  17. Interpreter in Criminal Cases: Allrounders First!

    Science.gov (United States)

    Frid, Arthur

    1974-01-01

    The interpreter in criminal cases generally has had a purely linguistic training with no difference from the education received by his colleague interpreters. The position of interpreters in criminal cases is vague and their role depends to a large extent on individual interpretation of officials involved in the criminal procedure. Improvements on…

  18. Antimicrobial Resistance

    Science.gov (United States)

    ... least 10 countries (Australia, Austria, Canada, France, Japan, Norway, Slovenia, South Africa, Sweden and the United Kingdom ... plan Global report on surveillance Country situation analysis Policy to combat antimicrobial resistance More on antimicrobial resistance ...

  19. Antimicrobial Resistance

    Science.gov (United States)

    ... can prevent and manage antimicrobial resistance. It is collaborating with partners to strengthen the evidence base and ... on the global action plan. WHO has been leading multiple initiatives to address antimicrobial resistance: World Antibiotic ...

  20. Influence of Heat Treatments on the Corrosion Resistance of Medium -Carbon Steel using Sulfuric Spring Water

    Directory of Open Access Journals (Sweden)

    Ikhlas Basheer

    2015-02-01

    Full Text Available The corrosion is one of the important problems that may be occur to the parts of machinery and equipment after manufactured and when used as a result of exposure to corrosive media. Plain-carbon steel is considered as one of the most common minerals used in industrial applications. Some of heat treatments can have direct effect on the corrosion rate of steel by building up galvanic corrosion cells between its microscopic phases. Therefore, to adopt one of kinds of the plain-carbon steel and the most commonly used in industry to be study subject, that is medium carbon steel and took samples of this steel has been treated thermally in three methods which the normalising, annealing, and hardening .The corrosive media used in the research is Sulfuric Spring, it contains many chemical compounds to show its influence on the corrosion of steel. The weight loss method is used to determine corrosion rate and to compare between the results obtained, show that the greatest corrosion resistance of the annealed steel and the corrosion resistance of the hardened steel is the lowest while the corrosion  resistance of the normalised steel is in-between them.         Calcium carbonate was formed on the metal surface which acts as an isolating layer which decrease corrosion rate with time

  1. REQUIREMENTS FOR A GENERAL INTERPRETATION THEORY

    Directory of Open Access Journals (Sweden)

    Anda Laura Lungu Petruescu

    2013-06-01

    Full Text Available Time has proved that Economic Analysis is not enough as to ensure all the needs of the economic field. The present study wishes to propose a new approach method of the economic phenomena and processes based on the researches made outside the economic space- a new general interpretation theory- which is centered on the human being as the basic actor of economy. A general interpretation theory must assure the interpretation of the causalities among the economic phenomena and processes- causal interpretation; the interpretation of the correlations and dependencies among indicators- normative interpretation; the interpretation of social and communicational processes in economic organizations- social and communicational interpretation; the interpretation of the community status of companies- transsocial interpretation; the interpretation of the purposes of human activities and their coherency – teleological interpretation; the interpretation of equilibrium/ disequilibrium from inside the economic systems- optimality interpretation. In order to respond to such demands, rigor, pragmatism, praxiology and contextual connectors are required. In order to progress, the economic science must improve its language, both its syntax and its semantics. The clarity of exposure requires a language clarity and the scientific theory progress asks for the need of hypotheses in the building of the theories. The switch from the common language to the symbolic one means the switch from ambiguity to rigor and rationality, that is order in thinking. But order implies structure, which implies formalization. Our paper should be a plea for these requirements, requirements which should be fulfilled by a modern interpretation theory.

  2. An open room for interpretation

    DEFF Research Database (Denmark)

    Tofte-Hansen, Inge

    2015-01-01

    Based on a concept that I have developed, which is called: "An open room for interpretation", the following article states that creative work and aesthetic expression in a pedagogical context with 2-6 years old children must give space for the children's own expressions. To teach music should...... not only be seen as a learning task where initiative and product is defined by the teacher. In contrast, I suggest that creative activities and aesthetic processes must be seen as an interaction between children's immediate physicality and curiosity and the teacher's musical skills and abilities to follow...

  3. Touch design and narrative interpretation

    DEFF Research Database (Denmark)

    Zhao, Sumin; Unsworth, Len

    2016-01-01

    and the Bottle in depth, and illustrate how interactive design elements help to create an interpretative possibility of the story. We suggest that a better understanding of interactive touch design would promote more effective adult-child interactions around mobile applications....... of technology, but also a resource for meaning making. We distinguish two basic types of interactivity—intra-text and extra-text—incorporated in the touch design, and explore the different functions they perform in a broad range of picture book apps. In particular, we look at the app version of The Heart...

  4. Interpreting CNNs via Decision Trees

    OpenAIRE

    Zhang, Quanshi; Yang, Yu; Wu, Ying Nian; Zhu, Song-Chun

    2018-01-01

    This paper presents a method to learn a decision tree to quantitatively explain the logic of each prediction of a pre-trained convolutional neural networks (CNNs). Our method boosts the following two aspects of network interpretability. 1) In the CNN, each filter in a high conv-layer must represent a specific object part, instead of describing mixed patterns without clear meanings. 2) People can explain each specific prediction made by the CNN at the semantic level using a decision tree, i.e....

  5. Beyond Student Resistance: A Pedagogy of Possibility.

    Science.gov (United States)

    Lindquist, Barbara

    1994-01-01

    Critiques the concept of resistance in interpreting students' behaviors and attitudes, examining political, social, and psychological connotations of resistance and contradictory ways that educators employ the concept. The paper explains limitations imposed on education by the concept, noting the work of educators who reassess the implications of…

  6. Antibiotic resistance

    Directory of Open Access Journals (Sweden)

    Marianne Frieri

    2017-07-01

    Full Text Available Summary: Antimicrobial resistance in bacterial pathogens is a challenge that is associated with high morbidity and mortality. Multidrug resistance patterns in Gram-positive and -negative bacteria are difficult to treat and may even be untreatable with conventional antibiotics. There is currently a shortage of effective therapies, lack of successful prevention measures, and only a few new antibiotics, which require development of novel treatment options and alternative antimicrobial therapies. Biofilms are involved in multidrug resistance and can present challenges for infection control. Virulence, Staphylococcus aureus, Clostridium difficile infection, vancomycin-resistant enterococci, and control in the Emergency Department are also discussed. Keywords: Antibiotic resistance, Biofilms, Infections, Public health, Emergency Department

  7. Interpretation of ultrasonic images; Interpretation von Ultraschall-Abbildungen

    Energy Technology Data Exchange (ETDEWEB)

    Mueller, W; Schmitz, V; Kroening, M [Fraunhofer-Institut fuer Zerstoerungsfreie Pruefverfahren, Saarbruecken (Germany)

    1998-11-01

    During the evaluation of ultrasonic images, e.g. SAFT-reconstructed B-scan images (SAFT=Synthetic Aperture Focusing Technique) it is often difficult to decide, what is the origin of reconstructed image points: were they caused by defects, specimens geometry or mode-conversions. To facilitate this evaluation a tool based on the comparison of data was developed. Different kinds of data comparison are possible: identification of that RF-signals, which caused the reconstructed image point. This is the comparison of a reconstructed image with the corresponding RF-data. Comparison of two reconstructed images performing a superposition using logical operators. In this case e.g. the reconstruction of an unknown reflector is compared with that of a known one. Comparison of raw-RF-data by simultaneous scanning through two data sets. Here the echoes of an unknown reflector are compared with the echoes of a known one. The necessary datasets of known reflectors may be generated experimentally on reference reflectors or modelled. The aim is the identification of the reflector type, e.g. cracklike or not, the determination of position, size and orientation as well as the identification of accompanying satellite echoes. The interpretation of the SAFT-reconstructed B-scan image is carried out by a complete description of the reflector. In addition to the aim of interpretation the tool described is well suited to educate and train ultrasonic testers. (orig./MM) [Deutsch] Bei der Auswertung von Ultraschall-Abbildungen, z.B. SAFT-rekonstruierten B-Bildern (SAFT=Synthetische Apertur Fokus Technik), ist es oft schwierig zu entscheiden, wo rekonstruierte Bildpunkte herruehren: wurden sie durch Materialfehler, Bauteilgeometrie oder durch Wellenumwandlungen versursacht. Um diese Auswertung zu erleichtern, wurde ein Werkzeug entwickelt, welches auf dem Vergleich von Datensaetzen basiert. Es koennen verschiedene Arten des Datenvergleichs durchgefuehrt werden: Identifikation der HF

  8. Wilhelm Wundt's Theory of Interpretation

    Directory of Open Access Journals (Sweden)

    Jochen Fahrenberg

    2008-09-01

    Full Text Available Wilhelm WUNDT was a pioneer in experimental and physiological psychology. However, his theory of interpretation (hermeneutics remains virtually neglected. According to WUNDT psychology belongs to the domain of the humanities (Geisteswissenschaften, and, throughout his books and research, he advocated two basic methodologies: experimentation (as the means of controlled self-observation and interpretative analysis of mental processes and products. He was an experimental psychologist and a profound expert in traditional hermeneutics. Today, he still may be acknowledged as the author of the monumental Völkerpsychologie, but not his advances in epistemology and methodology. His subsequent work, the Logik (1908/1921, contains about 120 pages on hermeneutics. In the present article a number of issues are addressed. Noteworthy was WUNDT's general intention to account for the logical constituents and the psychological process of understanding, and his reflections on quality control. In general, WUNDT demanded methodological pluralism and a complementary approach to the study of consciousness and neurophysiological processes. In the present paper WUNDT's approach is related to the continuing controversy on basic issues in methodology; e.g. experimental and statistical methods vs. qualitative (hermeneutic methods. Varied explanations are given for the one-sided or distorted reception of WUNDT's methodology. Presently, in Germany the basic program of study in psychology lacks thorough teaching and training in qualitative (hermeneutic methods. Appropriate courses are not included in the curricula, in contrast to the training in experimental design, observation methods, and statistics. URN: urn:nbn:de:0114-fqs0803291

  9. An application of Extended Normalisation Process Theory in a randomised controlled trial of a complex social intervention: Process evaluation of the Strengthening Families Programme (10-14) in Wales, UK.

    Science.gov (United States)

    Segrott, Jeremy; Murphy, Simon; Rothwell, Heather; Scourfield, Jonathan; Foxcroft, David; Gillespie, David; Holliday, Jo; Hood, Kerenza; Hurlow, Claire; Morgan-Trimmer, Sarah; Phillips, Ceri; Reed, Hayley; Roberts, Zoe; Moore, Laurence

    2017-12-01

    Process evaluations generate important data on the extent to which interventions are delivered as intended. However, the tendency to focus only on assessment of pre-specified structural aspects of fidelity has been criticised for paying insufficient attention to implementation processes and how intervention-context interactions influence programme delivery. This paper reports findings from a process evaluation nested within a randomised controlled trial of the Strengthening Families Programme 10-14 (SFP 10-14) in Wales, UK. It uses Extended Normalisation Process Theory to theorise how interaction between SFP 10-14 and local delivery systems - particularly practitioner commitment/capability and organisational capacity - influenced delivery of intended programme activities: fidelity (adherence to SFP 10-14 content and implementation requirements); dose delivered; dose received (participant engagement); participant recruitment and reach (intervention attendance). A mixed methods design was utilised. Fidelity assessment sheets (completed by practitioners), structured observation by researchers, and routine data were used to assess: adherence to programme content; staffing numbers and consistency; recruitment/retention; and group size and composition. Interviews with practitioners explored implementation processes and context. Adherence to programme content was high - with some variation, linked to practitioner commitment to, and understanding of, the intervention's content and mechanisms. Variation in adherence rates was associated with the extent to which multi-agency delivery team planning meetings were held. Recruitment challenges meant that targets for group size/composition were not always met, but did not affect adherence levels or family engagement. Targets for staffing numbers and consistency were achieved, though capacity within multi-agency networks reduced over time. Extended Normalisation Process Theory provided a useful framework for assessing

  10. A new interpretation of chaos

    International Nuclear Information System (INIS)

    Luo Chuanwen; Wang Gang; Wang Chuncheng; Wei Junjie

    2009-01-01

    The concepts of uniform index and expectation uniform index are two mathematical descriptions of the uniformity and the mean uniformity of a finite set in a polyhedron. The concepts of instantaneous chaometry (ICM) and k step chaometry (k SCM) are introduced in order to apply the method in statistics for studying the nonlinear difference equations. It is found that k step chaometry is an indirect estimation of the expectation uniform index. The simulation illustrate that the expectation uniform index for the Lorenz System is increasing linearly, but increasing nonlinearly for the Chen's System with parameter b. In other words, the orbits for each system become more and more uniform with parameter b increasing. Finally, a conjecture is also brought forward, which implies that chaos can be interpreted by its orbit's mean uniformity described by the expectation uniform index and indirectly estimated by k SCM. The k SCM of the heart rate showes the feeble and old process of the heart.

  11. APL interpreter on MITRA-15

    International Nuclear Information System (INIS)

    Davcev, Danco

    1975-01-01

    APL in its present forms is an ideal instrument for the establishment of logic systems since it requires no specific declaration of type or form of variables. An APL system for C II computer of the MITRA series is described, with the following minimum configuration: MITRA central unit, 16-bit 32 K word memory, disc with fixed or mobile heads, type 4013 TEKTRONIX visualisation system. The originality of our APL interpreter on MITRA 15 lies in the use of a virtual memory system with pages of 128 word size. The so-called beating process is used to set up APL operators: the selection expressions in the tables may be evaluated without any manipulation of the values. (author) [fr

  12. Interpretation of neonatal chest radiography

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Hye Kyung [Dept. of Radiology, Kangwon National University Hospital, Chuncheon (Korea, Republic of)

    2016-05-15

    Plain radiographs for infants in the neonatal intensive care unit are obtained using the portable X-ray equipment in order to evaluate the neonatal lungs and also to check the position of the tubes and catheters used for monitoring critically-ill neonates. Neonatal respiratory distress is caused by a variety of medical or surgical disease conditions. Clinical information about the gestational week, respiratory symptoms, and any events during delivery is essential for interpretation of the neonatal chest radiographs. Awareness of common chest abnormality in the prematurely born or term babies is also very important for chest evaluation in the newborn. Furthermore, knowledge about complications such as air leaks and bronchopulmonary dysplasia following treatment are required to accurately inform the clinicians. The purpose of this article was to briefly review radiographic findings of chest diseases in newborns that are relatively common in daily practice.

  13. Interpreting the cosmic ray composition

    International Nuclear Information System (INIS)

    O'C Drury, L.; Ellisson, D.C; Meyer, J.-P.

    2000-01-01

    The detailed pattern of elemental abundances in the Galactic Cosmic Rays is well determined at energies of a few GeV per nucleon. After correction for propagation effects the inferred source composition shows significant deviations from the standard pattern of Galactic elemental abundances. These deviations, surprisingly overabundances of the heavy elements relative to Hydrogen, are clearly a significant clue to the origin of the cosmic rays, but one which has proven very difficult to interpret. We have recently shown that the 'standard' model for the origin of the bulk of the Galactic cosmic rays, namely acceleration by the diffusive shock acceleration process at the strong shocks associated with supernova remnants, can quantitatively explain all features of the source composition if the acceleration occurs from a dusty interstellar medium. This success must be regarded as one of the stronger pieces of evidence in favour of the standard model

  14. Interpreting the cosmic ray composition

    Energy Technology Data Exchange (ETDEWEB)

    O' C Drury, L.; Ellisson, D.C; Meyer, J.-P

    2000-01-31

    The detailed pattern of elemental abundances in the Galactic Cosmic Rays is well determined at energies of a few GeV per nucleon. After correction for propagation effects the inferred source composition shows significant deviations from the standard pattern of Galactic elemental abundances. These deviations, surprisingly overabundances of the heavy elements relative to Hydrogen, are clearly a significant clue to the origin of the cosmic rays, but one which has proven very difficult to interpret. We have recently shown that the 'standard' model for the origin of the bulk of the Galactic cosmic rays, namely acceleration by the diffusive shock acceleration process at the strong shocks associated with supernova remnants, can quantitatively explain all features of the source composition if the acceleration occurs from a dusty interstellar medium. This success must be regarded as one of the stronger pieces of evidence in favour of the standard model.

  15. Interpretation of neonatal chest radiography

    International Nuclear Information System (INIS)

    Yoon, Hye Kyung

    2016-01-01

    Plain radiographs for infants in the neonatal intensive care unit are obtained using the portable X-ray equipment in order to evaluate the neonatal lungs and also to check the position of the tubes and catheters used for monitoring critically-ill neonates. Neonatal respiratory distress is caused by a variety of medical or surgical disease conditions. Clinical information about the gestational week, respiratory symptoms, and any events during delivery is essential for interpretation of the neonatal chest radiographs. Awareness of common chest abnormality in the prematurely born or term babies is also very important for chest evaluation in the newborn. Furthermore, knowledge about complications such as air leaks and bronchopulmonary dysplasia following treatment are required to accurately inform the clinicians. The purpose of this article was to briefly review radiographic findings of chest diseases in newborns that are relatively common in daily practice

  16. Defunctionalized Interpreters for Programming Languages

    DEFF Research Database (Denmark)

    Danvy, Olivier

    2008-01-01

    by Reynolds in ``Definitional Interpreters for Higher-Order Programming Languages'' for functional implementations of denotational semantics, natural semantics, and big-step abstract machines using closure conversion, CPS transformation, and defunctionalization. Over the last few years, the author and his......This document illustrates how functional implementations of formal semantics (structural operational semantics, reduction semantics, small-step and big-step abstract machines, natural semantics, and denotational semantics) can be transformed into each other. These transformations were foreshadowed...... students have further observed that functional implementations of small-step and of big-step abstract machines are related using fusion by fixed-point promotion and that functional implementations of reduction semantics and of small-step abstract machines are related using refocusing and transition...

  17. Concurrent LISP and its interpreter

    Energy Technology Data Exchange (ETDEWEB)

    Tabata, K; Sugimoto, S; Ohno, Y

    1981-01-01

    In the research field of artificial intelligence many languages have been developed based on LISP, such as Planner, Conniver and so on. They have been developed to give users many useful facilities, especially for describing flexible control structures. Backtracking and coroutine facilities are typical ones introduced into these languages. Compared with backtracking and coroutine facilities, multi-process description facilities are considered to be a better alternative for writing well-structured programs. This paper describes concurrent LISP, a new concurrent programming language based on LISP. Concurrent LISP is designed to provide simple and flexible facilities for multi-process description without changing the original language features of LISP. This paper also describes the concurrent LISP interpreter which has been implemented on a FACOM M-200 at the Data Processing Center of Kyoto University. 19 references.

  18. QUALITATIVE INTERPRETATION OF GALAXY SPECTRA

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez Almeida, J.; Morales-Luis, A. B. [Instituto de Astrofisica de Canarias, E-38205 La Laguna, Tenerife (Spain); Terlevich, R.; Terlevich, E. [Instituto Nacional de Astrofisica, Optica y Electronica, Tonantzintla, Puebla (Mexico); Cid Fernandes, R., E-mail: jos@iac.es, E-mail: abml@iac.es, E-mail: rjt@ast.cam.ac.uk, E-mail: eterlevi@inaoep.mx, E-mail: cid@astro.ufsc.br [Departamento de Fisica-CFM, Universidade Federal de Santa Catarina, P.O. Box 476, 88040-900 Florianopolis, SC (Brazil)

    2012-09-10

    We describe a simple step-by-step guide to qualitative interpretation of galaxy spectra. Rather than an alternative to existing automated tools, it is put forward as an instrument for quick-look analysis and for gaining physical insight when interpreting the outputs provided by automated tools. Though the recipe is for general application, it was developed for understanding the nature of the Automatic Spectroscopic K-means-based (ASK) template spectra. They resulted from the classification of all the galaxy spectra in the Sloan Digital Sky Survey data release 7, thus being a comprehensive representation of the galaxy spectra in the local universe. Using the recipe, we give a description of the properties of the gas and the stars that characterize the ASK classes, from those corresponding to passively evolving galaxies, to H II galaxies undergoing a galaxy-wide starburst. The qualitative analysis is found to be in excellent agreement with quantitative analyses of the same spectra. We compare the mean ages of the stellar populations with those inferred using the code STARLIGHT. We also examine the estimated gas-phase metallicity with the metallicities obtained using electron-temperature-based methods. A number of byproducts follow from the analysis. There is a tight correlation between the age of the stellar population and the metallicity of the gas, which is stronger than the correlations between galaxy mass and stellar age, and galaxy mass and gas metallicity. The galaxy spectra are known to follow a one-dimensional sequence, and we identify the luminosity-weighted mean stellar age as the affine parameter that describes the sequence. All ASK classes happen to have a significant fraction of old stars, although spectrum-wise they are outshined by the youngest populations. Old stars are metal-rich or metal-poor depending on whether they reside in passive galaxies or in star-forming galaxies.

  19. A modular interpretation of various cubic towers

    DEFF Research Database (Denmark)

    Anbar Meidl, Nurdagül; Bassa, Alp; Beelen, Peter

    2017-01-01

    In this article we give a Drinfeld modular interpretation for various towers of function fields meeting Zink's bound.......In this article we give a Drinfeld modular interpretation for various towers of function fields meeting Zink's bound....

  20. Issues related to interpretation of space imagery

    Energy Technology Data Exchange (ETDEWEB)

    Alferenok, A V; Przhiyalgovskii, Ye S

    1981-01-01

    A method for interpreting remotely derived data of various generalization levels (e.g. the northern section of the Chu-Sarysuiskaya basin) that suggests use of a uniform legend for interpretation of maps.

  1. Language production and interpretation linguistics meets cognition

    CERN Document Server

    Zeevat, Henk

    2014-01-01

    A model of production and interpretation of natural language utterances is developed which explains why communication is normally fast and successful. Interpretation is taken to be analogous with visual perception in finding the most probable hypothesis that explains the utterance.

  2. Semantic interpretation of search engine resultant

    Science.gov (United States)

    Nasution, M. K. M.

    2018-01-01

    In semantic, logical language can be interpreted in various forms, but the certainty of meaning is included in the uncertainty, which directly always influences the role of technology. One results of this uncertainty applies to search engines as user interfaces with information spaces such as the Web. Therefore, the behaviour of search engine results should be interpreted with certainty through semantic formulation as interpretation. Behaviour formulation shows there are various interpretations that can be done semantically either temporary, inclusion, or repeat.

  3. An Online Synchronous Test for Professional Interpreters

    Science.gov (United States)

    Chen, Nian-Shing; Ko, Leong

    2010-01-01

    This article is based on an experiment designed to conduct an interpreting test for multiple candidates online, using web-based synchronous cyber classrooms. The test model was based on the accreditation test for Professional Interpreters produced by the National Accreditation Authority of Translators and Interpreters (NAATI) in Australia.…

  4. Modular interpreters with implicit context propagation

    NARCIS (Netherlands)

    P.A. Inostroza Valdera (Pablo); T. van der Storm (Tijs)

    2017-01-01

    textabstractModular interpreters are a crucial first step towards component-based language development: instead of writing language interpreters from scratch, they can be assembled from reusable, semantic building blocks. Unfortunately, traditional language interpreters can be hard to extend because

  5. Using Playing Cards to Differentiate Probability Interpretations

    Science.gov (United States)

    López Puga, Jorge

    2014-01-01

    The aprioristic (classical, naïve and symmetric) and frequentist interpretations of probability are commonly known. Bayesian or subjective interpretation of probability is receiving increasing attention. This paper describes an activity to help students differentiate between the three types of probability interpretations.

  6. Children's Comprehension of Metaphor: A Piagetian Interpretation

    Science.gov (United States)

    Smith, J. W. A.

    1976-01-01

    When the descriptive interpretations that sixth and eighth graders provided for metaphors selected from fifth-grade readers were examined in a Piagetian framework, the poorest interpretations showed characteristics of concrete and pre-operational thought, while the best interpretations showed characteristics of formal operational thought. (RL)

  7. Observations on resistive wall modes

    International Nuclear Information System (INIS)

    Gerwin, R.A.; Finn, J.M.

    1996-01-01

    Several results on resistive wall modes and their application to tokamaks are presented. First, it is observed that in the presence of collisional parallel dynamics there is an exact cancellation to lowest order of the dissipative and sound wave effects for an ideal Ohm's law. This is easily traced to the fact that the parallel dynamics occurs along the perturbed magnetic field lines for such electromagnetic modes. Such a cancellation does not occur in the resistive layer of a tearing-like mode. The relevance to models for resistive wall modes using an electrostatic Hammett-Perkins type operator to model Landau damping will be discussed. Second, we observe that with an ideal Ohm's law, resistive wall modes can be destabilized by rotation in that part of parameter space in which the ideal MHD modes are stable with the wall at infinity. This effect can easily be explained by interpreting the resistive wall instability in terms of mode coupling between the backward stable MHD mode and a stable mode locked into the wall. Such an effect can occur for very small rotation for tearing-resistive wall modes in which inertia dominates viscosity in the layer, but the mode is stabilized by further rotation. For modes for which viscosity dominates in the layer, rotation is purely stabilizing. For both tearing models, a somewhat higher rotation frequency gives stability essentially whenever the tearing mode is stable with a perfectly conducting wall. These tearing/resistive wall results axe also simply explained in terms of mode coupling. It has been shown that resonant external ideal modes can be stabilized in the presence of resistive wall and resistive plasma with rotation of order the nominal tearing mode growth rate. We show that these modes behave as resistive wall tearing modes in the sense above. This strengthens the suggestion that rotational stabilization of the external kink with a resistive wall is due to the presence of resistive layers, even for ideal modes

  8. Resistant Hypertension.

    Science.gov (United States)

    Doroszko, Adrian; Janus, Agnieszka; Szahidewicz-Krupska, Ewa; Mazur, Grzegorz; Derkacz, Arkadiusz

    2016-01-01

    Resistant hypertension is a severe medical condition which is estimated to appear in 9-18% of hypertensive patients. Due to higher cardiovascular risk, this disorder requires special diagnosis and treatment. The heterogeneous etiology, risk factors and comorbidities of resistant hypertension stand in need of sophisticated evaluation to confirm the diagnosis and select the best therapeutic options, which should consider lifestyle modifications as well as pharmacological and interventional treatment. After having excluded pseudohypertension, inappropriate blood pressure measurement and control as well as the white coat effect, suspicion of resistant hypertension requires an analysis of drugs which the hypertensive patient is treated with. According to one definition - ineffective treatment with 3 or more antihypertensive drugs including diuretics makes it possible to diagnose resistant hypertension. A multidrug therapy including angiotensin - converting enzyme inhibitors, angiotensin II receptor blockers, beta blockers, diuretics, long-acting calcium channel blockers and mineralocorticoid receptor antagonists has been demonstrated to be effective in resistant hypertension treatment. Nevertheless, optional, innovative therapies, e.g. a renal denervation or baroreflex activation, may create a novel pathway of blood pressure lowering procedures. The right diagnosis of this disease needs to eliminate the secondary causes of resistant hypertension e.g. obstructive sleep apnea, atherosclerosis and renal or hormonal disorders. This paper briefly summarizes the identification of the causes of resistant hypertension and therapeutic strategies, which may contribute to the proper diagnosis and an improvement of the long term management of resistant hypertension.

  9. Camptothecin resistance

    DEFF Research Database (Denmark)

    Brangi, M; Litman, Thomas; Ciotti, M

    1999-01-01

    . Glucuronides were found at equal levels in both parental and resistant colon cancer cell lines for epirubicin and to a lesser extent for SN-38 and mitoxantrone. Low levels of glucuronidation could also be detected in the resistant breast cancer cells. These results were confirmed by analysis of the UGT1A...

  10. A robust interpretation of duration calculus

    DEFF Research Database (Denmark)

    Franzle, M.; Hansen, Michael Reichhardt

    2005-01-01

    We transfer the concept of robust interpretation from arithmetic first-order theories to metric-time temporal logics. The idea is that the interpretation of a formula is robust iff its truth value does not change under small variation of the constants in the formula. Exemplifying this on Duration...... Calculus (DC), our findings are that the robust interpretation of DC is equivalent to a multi-valued interpretation that uses the real numbers as semantic domain and assigns Lipschitz-continuous interpretations to all operators of DC. Furthermore, this continuity permits approximation between discrete...

  11. IMAGE INTERPRETATION OF COASTAL AREAS

    Directory of Open Access Journals (Sweden)

    M. A. Lazaridou

    2012-07-01

    Full Text Available Coasts were formed with the overall shape of earth's surface. Τhey represent a landform, as determined by the science of geomorphology. Being the boundary between land and sea, they present important features – particularities such as water currents, waves, winds, estuaries, drainage network, pollution etc. Coasts are examined at various levels: continents – oceans, states – large seas, as for example Mediterranean Sea. Greece, because of its horizontal and vertical partitioning, presents great extent and variety of coasts as mainland, peninsulas and islands. Depending on geomorphology, geology, soils, hydrology, land use of the inland and the coasts themselves, these are very diverse. Photogrammetry and Remote Sensing (defined by Statute II of ISPRS is the art, science, and technology of obtaining reliable information from non-contact imaging and other sensor systems about the Earth and its environment, and other physical objects and of processes through recording, measuring, analyzing and representation. This paper concerns critical considerations on the above. It also includes the case of Thessaloniki coasts in Greece, particularly river estuaries areas (river delta. The study of coastal areas of the wide surroundings of Thessaloniki city includes visual image interpretation – digital image processing techniques on satellite data of high spatial resolution.

  12. Interpreting Electromagnetic Reflections In Glaciology

    Science.gov (United States)

    Eisen, O.; Nixdorf, U.; Wilhelms, F.; Steinhage, D.; Miller, H.

    Electromagnetic reflection (EMR) measurements are active remote sensing methods that have become a major tool for glaciological investigations. Although the basic pro- cesses are well understood, the unambiguous interpretation of EMR data, especially internal layering, still requires further information. The Antacrtic ice sheet provides a unique setting for investigating the relation between physical­chemical properties of ice and EMR data. Cold ice, smooth surface topography, and low accumulation facilitates matters to use low energy ground penetrating radar (GPR) devices to pene- trate several tens to hundreds of meters of ice, covering several thousands of years of snow deposition history. Thus, sufficient internal layers, primarily of volcanic origin, are recorded to enable studies on a local and regional scale. Based on dated ice core records, GPR measurements at various frequencies, and airborne radio-echo sound- ing (RES) from Dronning Maud Land (DML), Antarctica, combined with numerical modeling techniques, we investigate the influence of internal layering characteristics and properties of the propagating electromagnetic wave on EMR data.

  13. Guide to Magellan image interpretation

    Science.gov (United States)

    Ford, John P.; Plaut, Jeffrey J.; Weitz, Catherine M.; Farr, Tom G.; Senske, David A.; Stofan, Ellen R.; Michaels, Gregory; Parker, Timothy J.; Fulton, D. (Editor)

    1993-01-01

    An overview of Magellan Mission requirements, radar system characteristics, and methods of data collection is followed by a description of the image data, mosaic formats, areal coverage, resolution, and pixel DN-to-dB conversion. The availability and sources of image data are outlined. Applications of the altimeter data to estimate relief, Fresnel reflectivity, and surface slope, and the radiometer data to derive microwave emissivity are summarized and illustrated in conjunction with corresponding SAR image data. Same-side and opposite-side stereo images provide examples of parallax differences from which to measure relief with a lateral resolution many times greater than that of the altimeter. Basic radar interactions with geologic surfaces are discussed with respect to radar-imaging geometry, surface roughness, backscatter modeling, and dielectric constant. Techniques are described for interpreting the geomorphology and surface properties of surficial features, impact craters, tectonically deformed terrain, and volcanic landforms. The morphologic characteristics that distinguish impact craters from volcanic craters are defined. Criteria for discriminating extensional and compressional origins of tectonic features are discussed. Volcanic edifices, constructs, and lava channels are readily identified from their radar outlines in images. Geologic map units are identified on the basis of surface texture, image brightness, pattern, and morphology. Superposition, cross-cutting relations, and areal distribution of the units serve to elucidate the geologic history.

  14. Monitoring and interpreting bioremediation effectiveness

    International Nuclear Information System (INIS)

    Bragg, J.R.; Prince, R.C.; Harner, J.; Atlas, R.M.

    1993-01-01

    Following the Exxon Valdez oil spill in 1989, extensive research was conducted by the US Environments Protection Agency and Exxon to develop and implement bioremediation techniques for oil spill cleanup. A key challenge of this program was to develop effective methods for monitoring and interpreting bioremediation effectiveness on extremely heterogenous intertidal shorelines. Fertilizers were applied to shorelines at concentrations known to be safe, and effectiveness achieved in acceleration biodegradation of oil residues was measure using several techniques. This paper describes the most definitive method identified, which monitors biodegradation loss by measuring changes in ratios of hydrocarbons to hopane, a cycloalkane present in the oil that showed no measurable degradation. Rates of loss measured by the hopane ratio method have high levels of statistical confidence, and show that the fertilizer addition stimulated biodegradation rates as much a fivefold. Multiple regression analyses of data show that fertilizer addition of nitrogen in interstitial pore water per unit of oil load was the most important parameter affecting biodegradation rate, and results suggest that monitoring nitrogen concentrations in the subsurface pore water is preferred technique for determining fertilizer dosage and reapplication frequency

  15. Equivalent statistics and data interpretation.

    Science.gov (United States)

    Francis, Gregory

    2017-08-01

    Recent reform efforts in psychological science have led to a plethora of choices for scientists to analyze their data. A scientist making an inference about their data must now decide whether to report a p value, summarize the data with a standardized effect size and its confidence interval, report a Bayes Factor, or use other model comparison methods. To make good choices among these options, it is necessary for researchers to understand the characteristics of the various statistics used by the different analysis frameworks. Toward that end, this paper makes two contributions. First, it shows that for the case of a two-sample t test with known sample sizes, many different summary statistics are mathematically equivalent in the sense that they are based on the very same information in the data set. When the sample sizes are known, the p value provides as much information about a data set as the confidence interval of Cohen's d or a JZS Bayes factor. Second, this equivalence means that different analysis methods differ only in their interpretation of the empirical data. At first glance, it might seem that mathematical equivalence of the statistics suggests that it does not matter much which statistic is reported, but the opposite is true because the appropriateness of a reported statistic is relative to the inference it promotes. Accordingly, scientists should choose an analysis method appropriate for their scientific investigation. A direct comparison of the different inferential frameworks provides some guidance for scientists to make good choices and improve scientific practice.

  16. Antibiotic Resistance

    DEFF Research Database (Denmark)

    Munck, Christian

    morbidity and mortality as well as an increase in the cost of treatment. Understanding how bacteria respond to antibiotic exposure gives the foundations for a rational approach to counteract antimicrobial resistance. In the work presented in this thesis, I explore the two fundamental sources...... of antimicrobial resistance: (1) adaptive mutations and (2) horizontal acquisition of resistance genes from antibiotic gene reservoirs. By studying the geno- and phenotypic changes of E. coli in response to single and drug-pair exposures, I uncover the evolutionary trajectories leading to adaptive resistance. I...... to rationally design drug combinations that limit the evolution of antibiotic resistance due to counteracting evolutionary trajectories. My results highlight that an in-depth knowledge about the genetic responses to the individual antimicrobial compounds enables the prediction of responses to drug combinations...

  17. Who can monitor the court interpreter's performance?

    DEFF Research Database (Denmark)

    Martinsen, Bodil

    2009-01-01

    and the conflict about her competence was negotiated. Because of this unusual constellation, combined with a multi-method approach, this single case study can shed some light on the question of the participants' ability to monitor the interpreter's performance. Legal professional users of interpreters tend......  Who can monitor the court interpreter's performance? Results of a case study This paper presents the results of a case study of an unusual interpreting event in a Danish courtroom setting. During the trial, the interpreter's non-normative performance was explicitly criticised by the audience...... are far less transparent for the legal participants than they normally assume. This problem, in turn, stresses the importance of a) the interpreter's competence and self-awareness and b) the use of check interpreters.  ...

  18. Laterally constrained inversion for CSAMT data interpretation

    Science.gov (United States)

    Wang, Ruo; Yin, Changchun; Wang, Miaoyue; Di, Qingyun

    2015-10-01

    Laterally constrained inversion (LCI) has been successfully applied to the inversion of dc resistivity, TEM and airborne EM data. However, it hasn't been yet applied to the interpretation of controlled-source audio-frequency magnetotelluric (CSAMT) data. In this paper, we apply the LCI method for CSAMT data inversion by preconditioning the Jacobian matrix. We apply a weighting matrix to Jacobian to balance the sensitivity of model parameters, so that the resolution with respect to different model parameters becomes more uniform. Numerical experiments confirm that this can improve the convergence of the inversion. We first invert a synthetic dataset with and without noise to investigate the effect of LCI applications to CSAMT data, for the noise free data, the results show that the LCI method can recover the true model better compared to the traditional single-station inversion; and for the noisy data, the true model is recovered even with a noise level of 8%, indicating that LCI inversions are to some extent noise insensitive. Then, we re-invert two CSAMT datasets collected respectively in a watershed and a coal mine area in Northern China and compare our results with those from previous inversions. The comparison with the previous inversion in a coal mine shows that LCI method delivers smoother layer interfaces that well correlate to seismic data, while comparison with a global searching algorithm of simulated annealing (SA) in a watershed shows that though both methods deliver very similar good results, however, LCI algorithm presented in this paper runs much faster. The inversion results for the coal mine CSAMT survey show that a conductive water-bearing zone that was not revealed by the previous inversions has been identified by the LCI. This further demonstrates that the method presented in this paper works for CSAMT data inversion.

  19. Resistance and Security Index of Networks: Structural Information Perspective of Network Security

    Science.gov (United States)

    Li, Angsheng; Hu, Qifu; Liu, Jun; Pan, Yicheng

    2016-01-01

    Recently, Li and Pan defined the metric of the K-dimensional structure entropy of a structured noisy dataset G to be the information that controls the formation of the K-dimensional structure of G that is evolved by the rules, order and laws of G, excluding the random variations that occur in G. Here, we propose the notion of resistance of networks based on the one- and two-dimensional structural information of graphs. Given a graph G, we define the resistance of G, written , as the greatest overall number of bits required to determine the code of the module that is accessible via random walks with stationary distribution in G, from which the random walks cannot escape. We show that the resistance of networks follows the resistance law of networks, that is, for a network G, the resistance of G is , where and are the one- and two-dimensional structure entropies of G, respectively. Based on the resistance law, we define the security index of a network G to be the normalised resistance of G, that is, . We show that the resistance and security index are both well-defined measures for the security of the networks. PMID:27255783

  20. Resistance and Security Index of Networks: Structural Information Perspective of Network Security.

    Science.gov (United States)

    Li, Angsheng; Hu, Qifu; Liu, Jun; Pan, Yicheng

    2016-06-03

    Recently, Li and Pan defined the metric of the K-dimensional structure entropy of a structured noisy dataset G to be the information that controls the formation of the K-dimensional structure of G that is evolved by the rules, order and laws of G, excluding the random variations that occur in G. Here, we propose the notion of resistance of networks based on the one- and two-dimensional structural information of graphs. Given a graph G, we define the resistance of G, written , as the greatest overall number of bits required to determine the code of the module that is accessible via random walks with stationary distribution in G, from which the random walks cannot escape. We show that the resistance of networks follows the resistance law of networks, that is, for a network G, the resistance of G is , where and are the one- and two-dimensional structure entropies of G, respectively. Based on the resistance law, we define the security index of a network G to be the normalised resistance of G, that is, . We show that the resistance and security index are both well-defined measures for the security of the networks.

  1. Resistance and Security Index of Networks: Structural Information Perspective of Network Security

    Science.gov (United States)

    Li, Angsheng; Hu, Qifu; Liu, Jun; Pan, Yicheng

    2016-06-01

    Recently, Li and Pan defined the metric of the K-dimensional structure entropy of a structured noisy dataset G to be the information that controls the formation of the K-dimensional structure of G that is evolved by the rules, order and laws of G, excluding the random variations that occur in G. Here, we propose the notion of resistance of networks based on the one- and two-dimensional structural information of graphs. Given a graph G, we define the resistance of G, written , as the greatest overall number of bits required to determine the code of the module that is accessible via random walks with stationary distribution in G, from which the random walks cannot escape. We show that the resistance of networks follows the resistance law of networks, that is, for a network G, the resistance of G is , where and are the one- and two-dimensional structure entropies of G, respectively. Based on the resistance law, we define the security index of a network G to be the normalised resistance of G, that is, . We show that the resistance and security index are both well-defined measures for the security of the networks.

  2. The emergent Copenhagen interpretation of quantum mechanics

    Science.gov (United States)

    Hollowood, Timothy J.

    2014-05-01

    We introduce a new and conceptually simple interpretation of quantum mechanics based on reduced density matrices of sub-systems from which the standard Copenhagen interpretation emerges as an effective description of macroscopically large systems. This interpretation describes a world in which definite measurement results are obtained with probabilities that reproduce the Born rule. Wave function collapse is seen to be a useful but fundamentally unnecessary piece of prudent book keeping which is only valid for macro-systems. The new interpretation lies in a class of modal interpretations in that it applies to quantum systems that interact with a much larger environment. However, we show that it does not suffer from the problems that have plagued similar modal interpretations like macroscopic superpositions and rapid flipping between macroscopically distinct states. We describe how the interpretation fits neatly together with fully quantum formulations of statistical mechanics and that a measurement process can be viewed as a process of ergodicity breaking analogous to a phase transition. The key feature of the new interpretation is that joint probabilities for the ergodic subsets of states of disjoint macro-systems only arise as emergent quantities. Finally we give an account of the EPR-Bohm thought experiment and show that the interpretation implies the violation of the Bell inequality characteristic of quantum mechanics but in a way that is rather novel. The final conclusion is that the Copenhagen interpretation gives a completely satisfactory phenomenology of macro-systems interacting with micro-systems.

  3. The emergent Copenhagen interpretation of quantum mechanics

    International Nuclear Information System (INIS)

    Hollowood, Timothy J

    2014-01-01

    We introduce a new and conceptually simple interpretation of quantum mechanics based on reduced density matrices of sub-systems from which the standard Copenhagen interpretation emerges as an effective description of macroscopically large systems. This interpretation describes a world in which definite measurement results are obtained with probabilities that reproduce the Born rule. Wave function collapse is seen to be a useful but fundamentally unnecessary piece of prudent book keeping which is only valid for macro-systems. The new interpretation lies in a class of modal interpretations in that it applies to quantum systems that interact with a much larger environment. However, we show that it does not suffer from the problems that have plagued similar modal interpretations like macroscopic superpositions and rapid flipping between macroscopically distinct states. We describe how the interpretation fits neatly together with fully quantum formulations of statistical mechanics and that a measurement process can be viewed as a process of ergodicity breaking analogous to a phase transition. The key feature of the new interpretation is that joint probabilities for the ergodic subsets of states of disjoint macro-systems only arise as emergent quantities. Finally we give an account of the EPR–Bohm thought experiment and show that the interpretation implies the violation of the Bell inequality characteristic of quantum mechanics but in a way that is rather novel. The final conclusion is that the Copenhagen interpretation gives a completely satisfactory phenomenology of macro-systems interacting with micro-systems. (paper)

  4. Antiretroviral Resistance in HIV/AIDS Patients

    Science.gov (United States)

    Manosuthi, W.; MD

    2018-03-01

    The higher prevalence of HIV drug resistance was observed in areas with greater ART coverage. The HIV resistance-associated mutations occur when people have inadequate levels of antiretroviral drugs as well as inadequate potency, inadequate adherence, and preexisting resistance. The degree to drug cross-resistance is observed depends on the specific mutations and number of mutation accumulation. In the Southeast Asia region, the challenging of people with treatment failure is the availability and accessibility to subsequent new antiretroviral drugs to construct he second and salvage regimen. Genotypic resistance testing is a useful tool because it can identify the existing drug resistance-associated mutations under the selective drug pressure. Thus, understanding the basic interpretation of HIV drug resistance- associated mutation is useful in guiding clinical decisions for treatment-experienced people living with HIV.

  5. Antimicrobial Resistance

    Science.gov (United States)

    ... past two decades due to the increase in immunocompromised and elderly patients, increasing use of invasive indwelling ... aureus developing resistance to vancomycin, a very powerful antibiotic prescribed for the most intractable bacterial infections. In ...

  6. Drug Resistance

    Science.gov (United States)

    ... Drug-resistance testing is also recommended for all pregnant women with HIV before starting HIV medicines and also in some pregnant women already taking HIV medicines. Pregnant women will work with their health ...

  7. An information gap in DNA evidence interpretation.

    Directory of Open Access Journals (Sweden)

    Mark W Perlin

    Full Text Available Forensic DNA evidence often contains mixtures of multiple contributors, or is present in low template amounts. The resulting data signals may appear to be relatively uninformative when interpreted using qualitative inclusion-based methods. However, these same data can yield greater identification information when interpreted by computer using quantitative data-modeling methods. This study applies both qualitative and quantitative interpretation methods to a well-characterized DNA mixture and dilution data set, and compares the inferred match information. The results show that qualitative interpretation loses identification power at low culprit DNA quantities (below 100 pg, but that quantitative methods produce useful information down into the 10 pg range. Thus there is a ten-fold information gap that separates the qualitative and quantitative DNA mixture interpretation approaches. With low quantities of culprit DNA (10 pg to 100 pg, computer-based quantitative interpretation provides greater match sensitivity.

  8. Antimicrobial resistance

    DEFF Research Database (Denmark)

    Llor, Carl; Bjerrum, Lars

    2014-01-01

    Antimicrobial resistance is a global public health challenge, which has accelerated by the overuse of antibiotics worldwide. Increased antimicrobial resistance is the cause of severe infections, complications, longer hospital stays and increased mortality. Overprescribing of antibiotics......-the-counter sale of antibiotics, the use of antimicrobial stewardship programmes, the active participation of clinicians in audits, the utilization of valid rapid point-of-care tests, the promotion of delayed antibiotic prescribing strategies, the enhancement of communication skills with patients with the aid...

  9. Architectural design of an Algol interpreter

    Science.gov (United States)

    Jackson, C. K.

    1971-01-01

    The design of a syntax-directed interpreter for a subset of Algol is described. It is a conceptual design with sufficient details and completeness but as much independence of implementation as possible. The design includes a detailed description of a scanner, an analyzer described in the Floyd-Evans productions, a hash-coded symbol table, and an executor. Interpretation of sample programs is also provided to show how the interpreter functions.

  10. Model-Agnostic Interpretability of Machine Learning

    OpenAIRE

    Ribeiro, Marco Tulio; Singh, Sameer; Guestrin, Carlos

    2016-01-01

    Understanding why machine learning models behave the way they do empowers both system designers and end-users in many ways: in model selection, feature engineering, in order to trust and act upon the predictions, and in more intuitive user interfaces. Thus, interpretability has become a vital concern in machine learning, and work in the area of interpretable models has found renewed interest. In some applications, such models are as accurate as non-interpretable ones, and thus are preferred f...

  11. Interpreting quantum discord through quantum state merging

    International Nuclear Information System (INIS)

    Madhok, Vaibhav; Datta, Animesh

    2011-01-01

    We present an operational interpretation of quantum discord based on the quantum state merging protocol. Quantum discord is the markup in the cost of quantum communication in the process of quantum state merging, if one discards relevant prior information. Our interpretation has an intuitive explanation based on the strong subadditivity of von Neumann entropy. We use our result to provide operational interpretations of other quantities like the local purity and quantum deficit. Finally, we discuss in brief some instances where our interpretation is valid in the single-copy scenario.

  12. Mind, Matter, Information and Quantum Interpretations

    Directory of Open Access Journals (Sweden)

    Reza Maleeh

    2015-07-01

    Full Text Available In this paper I give a new information-theoretic analysis of the formalisms and interpretations of quantum mechanics (QM in general, and of two mainstream interpretations of quantum mechanics in particular: The Copenhagen interpretation and David Bohm’s interpretation of quantum mechanics. Adopting Juan G. Roederer’s reading of the notion of pragmatic information, I argue that pragmatic information is not applicable to the Copenhagen interpretation since the interpretation is primarily concerned with epistemology rather than ontology. However it perfectly fits Bohm’s ontological interpretation of quantum mechanics in the realms of biotic and artificial systems. Viewing Bohm’s interpretation of QM in the context of pragmatic information imposes serious limitations to the qualitative aspect of such an interpretation, making his extension of the notion active information to every level of reality illegitimate. Such limitations lead to the idea that, contrary to Bohm’s claim, mind is not a more subtle aspect of reality via the quantum potential as active information, but the quantum potential as it affects particles in the double-slit experiment represents the non-algorithmic aspect of the mind as a genuine information processing system. This will provide an information-based ground, firstly, for refreshing our views on quantum interpretations and secondly, for a novel qualitative theory of the relationship of mind and matter in which mind-like properties are exclusive attributes of living systems. To this end, I will also take an information-theoretic approach to the notion of intentionality as interpreted by John Searle.

  13. What is the cementation exponent? A new differential interpretation

    Science.gov (United States)

    Glover, P. W. J.

    2009-04-01

    Between 1950 and 2002 the total volume of reserves discovered has run to over 1500 Bbbl. for oil and 7.5 Tcf. for gas. Over half of these resources has already been produced, and has driven the global economy for the last fifty years. All of the assessments of the volume of hydrocarbon reserves were made using Archie's relationships (1942). It would be difficult, therefore, to overestimate the impact of either the petrophysical techniques or Archie's relationships on the worldwide economy. Archie's laws link the electrical resistivity of a rock to its porosity, to the resistivity of the water that saturates its pores, and to the fractional saturation of the pore space with the water, and are used to calculate the hydrocarbon saturation of the reservoir rock from which the reserves are then calculated. Archie's laws contain two exponents, m and n, which Archie called the cementation exponent and the saturation exponent, respectively. The conductivity of the hydrocarbon saturated rock is highly sensitive to changes in either exponent. However, despite the importance of the cementation exponent, few petrophysicists, commercial or academic, are able to describe its real physical meaning. The purpose of this contribution is to investigate the elusive physical meaning of the cementation exponent. We review the traditional interpretation of the cementation exponent and consider the extension of Archie's first law to two conducting phases. Consequently, we develop a new differential interpretation of the cementation exponent that is based on a new definition for the connectedness of the conducting phases in a porous medium. In this interpretation the connectedness of a porous medium is defined as the availability of pathways for transport, where the connectedness is the inverse of the formation resistivity factor, G = σo σw = 1 F (and may also be called the conductivity formation factor). Porosity is defined as the fractional amount of pore space in the usual manner

  14. The dynamics of the oesophageal squamous epithelium 'normalisation' process in patients with gastro-oesophageal reflux disease treated with long-term acid suppression or anti-reflux surgery.

    Science.gov (United States)

    Mastracci, L; Fiocca, R; Engström, C; Attwood, S; Ell, C; Galmiche, J P; Hatlebakk, J G; Långström, G; Eklund, S; Lind, T; Lundell, L

    2017-05-01

    Proton pump inhibitors and laparoscopic anti-reflux surgery (LARS) offer long-term symptom control to patients with gastro-oesophageal reflux disease (GERD). To evaluate the process of 'normalisation' of the squamous epithelium morphology of the distal oesophagus on these therapies. In the LOTUS trial, 554 patients with chronic GERD were randomised to receive either esomeprazole (20-40 mg daily) or LARS. After 5 years, 372 patients remained in the study (esomeprazole, 192; LARS, 180). Biopsies were taken at the Z-line and 2 cm above, at baseline, 1, 3 and 5 years. A severity score was calculated based on: papillae elongation, basal cell hyperplasia, intercellular space dilatations and eosinophilic infiltration. The epithelial proliferative activity was assessed by Ki-67 immunohistochemistry. A gradual improvement in all variables over 5 years was noted in both groups, at both the Z-line and 2 cm above. The severity score decreased from baseline at each subsequent time point in both groups (P refluxate seems to play the predominant role in restoring tissue morphology. © 2017 John Wiley & Sons Ltd.

  15. Effect of food matrix and thermal processing on the performance of a normalised quantitative real-time PCR approach for lupine (Lupinus albus) detection as a potential allergenic food.

    Science.gov (United States)

    Villa, Caterina; Costa, Joana; Gondar, Cristina; Oliveira, M Beatriz P P; Mafra, Isabel

    2018-10-01

    Lupine is widely used as an ingredient in diverse food products, but it is also a source of allergens. This work aimed at proposing a method to detect/quantify lupine as an allergen in processed foods based on a normalised real-time PCR assay targeting the Lup a 4 allergen-encoding gene of Lupinus albus. Sensitivities down to 0.0005%, 0.01% and 0.05% (w/w) of lupine in rice flour, wheat flour and bread, respectively, and 1 pg of L. albus DNA were obtained, with adequate real-time PCR performance parameters using the ΔCt method. Both food matrix and processing affected negatively the quantitative performance of the assay. The method was successfully validated with blind samples and applied to processed foods. Lupine was estimated between 4.12 and 22.9% in foods, with some results suggesting the common practice of precautionary labelling. In this work, useful and effective tools were proposed for the detection/quantification of lupine in food products. Copyright © 2018 Elsevier Ltd. All rights reserved.

  16. Resistant hypertension.

    Science.gov (United States)

    Wei, Fang-Fei; Zhang, Zhen-Yu; Huang, Qi-Fang; Yang, Wen-Yi; Staessen, Jan A

    2018-06-15

    The publication of the first non-randomised proof-of-concept trial of renal denervation as a treatment modality in treatment-resistant hypertension set the stage for a search for novel devices with the expectation that technology would reduce the burden of hypertension by reducing or eliminating the costly and lifelong use of blood pressure lowering medications. As we demonstrate in this review, this idea so attractive to manufacturers and invasive cardiologists and radiologists overlooked decades of careful pathophysiological research in a disease, which still remains enigmatic but remains the major cause of cardiovascular mortality worldwide. To make our point, we first reviewed the prevalence and risks associated with treatment-resistant hypertension. Next, we highlighted the key points required for the diagnosis of treatment-resistant hypertension, including the recording of the ambulatory blood pressure and the assessment of adherence to medication. Finally, we summarised new insights in the management of treatment-resistant hypertension by medication and devices and in the future research. Throughout our review, we focused on new evidence became available since 2013. Our conclusion is that optimising medical treatment based on simple algorithms remains the state of the art in treatment-resistant hypertension.

  17. A functional interpretation for nonstandard arithmetic

    NARCIS (Netherlands)

    van den Berg, B.; Briseid, E.; Safarik, P.

    2012-01-01

    We introduce constructive and classical systems for nonstandard arithmetic and show how variants of the functional interpretations due to Gödel and Shoenfield can be used to rewrite proofs performed in these systems into standard ones. These functional interpretations show in particular that our

  18. Interpretation of Subgroup Effects in Published Trials

    DEFF Research Database (Denmark)

    Hancock, Mark J; Kjær, Per; Korsholm, Lars

    2013-01-01

    With the rapidly expanding number of studies reporting on treatment subgroups come new challenges in analyzing and interpreting this sometimes complex area of the literature. This article discusses 3 important issues regarding the analysis and interpretation of existing trials or systematic revie...

  19. Gestalt descriptions embodiments and medical image interpretation

    DEFF Research Database (Denmark)

    Friis, Jan Kyrre Berg Olsen

    2017-01-01

    In this paper I will argue that medical specialists interpret and diagnose through technological mediations like X-ray and fMRI images, and by actualizing embodied skills tacitly they are determining the identity of objects in the perceptual field. The initial phase of human interpretation of vis...

  20. Interpreting Histograms. As Easy as It Seems?

    Science.gov (United States)

    Lem, Stephanie; Onghena, Patrick; Verschaffel, Lieven; Van Dooren, Wim

    2014-01-01

    Histograms are widely used, but recent studies have shown that they are not as easy to interpret as it might seem. In this article, we report on three studies on the interpretation of histograms in which we investigated, namely, (1) whether the misinterpretation by university students can be considered to be the result of heuristic reasoning, (2)…

  1. 75 FR 80746 - Interpretation of Rest Requirements

    Science.gov (United States)

    2010-12-23

    ... Whitlow Letter in its interpretations of section 121.471(g). See Air Transport Ass'n of America, Inc. v. F... 121.471(g) and 135.263(d) is interpreted in two different ways. See Air Transport Ass'n, 291 F.3d at...

  2. Interpretation Analysis as a Competitive Event.

    Science.gov (United States)

    Nading, Robert M.

    Interpretation analysis is a new and interesting event on the forensics horizon which appears to be attracting an ever larger number of supporters. This event, developed by Larry Lambert of Ball State University in 1989, requires a student to perform all three disciplines of forensic competition (interpretation, public speaking, and limited…

  3. Combinatorial Interpretation of General Eulerian Numbers

    OpenAIRE

    Tingyao Xiong; Jonathan I. Hall; Hung-Ping Tsao

    2014-01-01

    Since 1950s, mathematicians have successfully interpreted the traditional Eulerian numbers and $q-$Eulerian numbers combinatorially. In this paper, the authors give a combinatorial interpretation to the general Eulerian numbers defined on general arithmetic progressions { a, a+d, a+2d,...}.

  4. Gene set analysis for interpreting genetic studies

    DEFF Research Database (Denmark)

    Pers, Tune H

    2016-01-01

    Interpretation of genome-wide association study (GWAS) results is lacking behind the discovery of new genetic associations. Consequently, there is an urgent need for data-driven methods for interpreting genetic association studies. Gene set analysis (GSA) can identify aetiologic pathways...

  5. 12 CFR 609.920 - Interpretations.

    Science.gov (United States)

    2010-01-01

    ... and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM ELECTRONIC COMMERCE Interpretations and Definitions § 609.920 Interpretations. (a) E-SIGN preempts most statutes and regulations, including the Act... E-commerce as long as the safeguards of E-SIGN are met and its exceptions recognized. Generally, an...

  6. Educational principles and techniques for interpreters.

    Science.gov (United States)

    F. David Boulanger; John P. Smith

    1973-01-01

    Interpretation is in large part education, since it attempts to convey information, concepts, and principles while creating attitude changes and such emotional states as wonder, delight, and appreciation. Although interpreters might profit greatly by formal training in the principles and techniques of teaching, many have not had such training. Some means of making the...

  7. Optimality Theory and Lexical Interpretation and Selection

    NARCIS (Netherlands)

    Hogeweg, L.; Legendre, G.; Putnam, M.T.; de Swart, H.; Zaroukian, E.

    2016-01-01

    This chapter argues for an optimization approach to the selection and interpretation of words. Several advantages of such an approach to lexical semantics are discussed. First of all, it will be argued that competition, entailing that words and interpretations are always judged in relation to other

  8. Extending and embedding the Python interpreter

    NARCIS (Netherlands)

    G. van Rossum (Guido)

    1995-01-01

    textabstractPython is an interpreted, object-oriented programming language. This document describes how to write modules in C or C++ to extend the Python interpreter with new modules. Those modules can define new functions but also new object types and their methods. The document also describes

  9. Infusing Counseling Skills in Test Interpretation.

    Science.gov (United States)

    Rawlins, Melanie E.; And Others

    1991-01-01

    Presents an instructional model based on Neurolinguistic Programming that links counseling student course work in measurement and test interpretation with counseling techniques and theory. A process incorporating Neurolinguistic Programming patterns is outlined for teaching graduate students the counseling skills helpful in test interpretation.…

  10. Investigating deviations from norms in court interpreting

    DEFF Research Database (Denmark)

    Dubslaff, Friedel; Martinsen, Bodil

    Since Shlesinger (1989) discussed the applicability of translational norms to the field of interpreting, a number of scholars have advocated the use of this concept as a frame of reference in interpreting research (e.g. Harris 1990, Schjoldager 1994, 1995, Jansen 1995, Gile 1999, Garzone 2002). Due...... for the study, we intend to conduct interviews instead. The purpose of the study is to investigate deviations from translational norms in court interpreting. More specifically, we aim to identify and describe instances of deviant behaviour on the part of the interpreters, discuss signs of possible deviant...... speaking these languages. This example does not immediately indicate that Translation Studies might be able to contribute to, for example, an improvement of the training situation for the group of court interpreters mentioned above. However, in our opinion, there is reason to believe that TS can make...

  11. The transactional interpretation of quantum mechanics

    Science.gov (United States)

    Cramer, John G.

    2001-06-01

    The transactional interpretation of quantum mechanics [1] was originally published in 1986 and is now about 14 years old. It is an explicitly nonlocal and Lorentz invariant alternative to the Copenhagen interpretation. It interprets the formalism for a quantum interaction as describing a "handshake" between retarded waves (ψ) and advanced waves (ψ*) for each quantum event or "transaction" in which energy, momentum, angular momentum, and other conserved quantities are transferred. The transactional interpretation offers the advantages that (1) it is actually "visible" in the formalism of quantum mechanics, (2) it is economical, involving fewer independent assumptions than its rivals, (3) it is paradox-free, resolving all of the paradoxes of standard quantum theory including nonlocality and wave function collapse, (4) it does not give a privileged role to observers or measurements, and (5) it permits the visualization of quantum events. We will review the transactional interpretation and some of its applications to "quantum paradoxes."

  12. Nuclear log interpretation by first principle

    International Nuclear Information System (INIS)

    Oelgaard, P.L.

    1988-07-01

    A weakness connected to the present interpretation of nuclear borehole logs is that the interdependence of the various logs and physical effects of importance for the tools are not always taken into account in a correct way. Therefore a new approach to the interpretation of nuclear borehole logs is considered. It is based on the logs obtained with the natural gamma, the neutron porosity, the gamma density, and the pulsed neutron tools. For each of these tools a model, taking into account the important physical effects, is established. These models are incorporated into a computer programme which from the tool signals calculates, by use of iteration, a consistent set of the corresponding formation properties. In the paper the models developed for the four tools and the interpretation programme are briefly described. An example of the use of the interpretation programme is given and compared with a conventional interpretation. (author)

  13. Integrating Emotions Into the Critical Interpretive Synthesis.

    Science.gov (United States)

    McFerran, Katrina Skewes; Hense, Cherry; Medcalf, Laura; Murphy, Melissa; Fairchild, Rebecca

    2017-01-01

    Critical interpretive synthesis is a particular form of systematic review that critically examines the decisions made by authors while conducting and publishing about their research and practices. It differs from empirical syntheses of qualitative research by emphasizing the interpreted and constructed nature of this form of secondary analysis. In this article, we extend previous literature on critical interpretive syntheses by highlighting the integration of emotional responses when developing critical questions for interrogating the literature and interpreting results. Our extension of the critical interpretive synthesis is illustrated through examples from five studies examining literature in our own field of music therapy, as well as related fields of disability studies, mental health, music psychology, and child welfare. The methodology we have refined uses an iterative and recursive method that promotes increased critical awareness of the assumptions driving the production of research in health contexts. © The Author(s) 2016.

  14. Anticoagulant Resistance

    DEFF Research Database (Denmark)

    Heiberg, Ann-Charlotte

    Although sewer rat control is carried out in more than 80 % of all Danish municipalities, with usage of large amounts of anticoagulant rodenticides, knowledge on anticoagulant resistance among rats living in the sewers is limited. As rat problems in urban areas are believed to be related to sewer...... problems (70-90 % in UK and DK) unawareness of resistance amongst these populations of Brown rats may constitute a future control problem and knowledge on this issue has become crucial. Rats were captured in sewers from seven different locations in the suburban area of Copenhagen. Locations was chosen...... to represent different sewer rat management strategies i) no anticoagulants for approx. 20 years ii) no anticoagulants for the last 5 years and iii) continuous control for many years. Animals were tested for resistance to bromadiolone by Blood-Clotting Response test, as bromadiolone is the most frequently used...

  15. Reducing Resistance

    DEFF Research Database (Denmark)

    Lindell, Johanna

    care may influence decisions on antibiotic use. Based on video-and audio recordings of physician-patient consultations it is investigated how treatment recommendations are presented, can be changed, are forecast and explained, and finally, how they seemingly meet resistance and how this resistance......Antibiotic resistance is a growing public health problem both nationally and internationally, and efficient strategies are needed to reduce unnecessary use. This dissertation presents four research studies, which examine how communication between general practitioners and patients in Danish primary...... is responded to.The first study in the dissertation suggests that treatment recommendations on antibiotics are often done in a way that encourages patient acceptance. In extension of this, the second study of the dissertation examines a case, where acceptance of such a recommendation is changed into a shared...

  16. Interpretation of time-domain electromagnetic soundings in the Calico Hills area, Nevada Test Site, Nye County, Nevada

    International Nuclear Information System (INIS)

    Kauahikaua, J.

    1981-01-01

    A controlled source, time-domain electromagnetic (TDEM) sounding survey was conducted in the Calico Hills area of the Nevada Test Site (NTS). The goal of this survey was the determination of the geoelectric structure as an aid in the evaluation of the site for possible future storage of spent nuclear fuel or high-level nuclear waste. The data were initially interpreted with a simple scheme that produces an apparent resistivity versus depth curve from the vertical magnetic field data. These curves can be qualitatively interpreted much like standard Schlumberger resistivity sounding curves. Final interpretation made use of a layered-earth Marquardt inversion computer program (Kauahikaua, 1980). The results combined with those from a set of Schlumberger soundings in the area show that there is a moderately resistive basement at a depth no greater than 800 meters. The basement resistivity is greater than 100 ohm-meters

  17. Interpretation of time-domain electromagnetic soundings in the Calico Hills area, Nevada Test Site, Nye County, Nevada

    Science.gov (United States)

    Kauahikaua, J.

    A controlled source, time domain electromagnetic (TDEM) sounding survey was conducted in the Calico Hills area of the Nevada Test Site (NTS). The geoelectric structure was determined as an aid in the evaluation of the site for possible future storage of spent nuclear fuel or high level nuclear waste. The data were initially interpreted with a simple scheme that produces an apparent resistivity versus depth curve from the vertical magnetic field data. These curves are qualitatively interpreted much like standard Schlumberger resistivity sounding curves. Final interpretation made use of a layered earth Marquardt inversion computer program. The results combined with those from a set of Schlumberger soundings in the area show that there is a moderately resistive basement at a depth no greater than 800 meters. The basement resistivity is greater than 100 ohm meters.

  18. A dissent from the many dissents from Attorney General Ashcroft's interpretation of the Controlled Substances Act.

    Science.gov (United States)

    Spindelman, Marc

    2003-01-01

    In this essay, Professor Marc Spindelman examines the states' rights arguments that have been deployed in the Oregon v. Ashcroft litigation to challenge Attorney General John Ashcroft's interpretation of the federal Controlled Substances Act. Professor Spindelman criticizes those arguments as reflecting bad politics--politics of complicity--that self-styled liberals should resist and reject.

  19. A Nordic Approach to the Interpretation of the European Convention on Human Rights?

    DEFF Research Database (Denmark)

    Rytter, Jens Elo

    2017-01-01

    Based on dissenting opinions involvin gnordic judges, the article draws the contours of a common Nordic approach to the Interpretation of the ECHR, chcaracterized by reluctance to move beyond textual limits, reliance on preparatory works, and resistance towards imposing obligations in the political...

  20. electrical resistivity investigation of the groundwater potential in ...

    African Journals Online (AJOL)

    The VES data generated were processed and interpreted using partial curve matching ... electrical sounding, a technique of electrical resistivity method in identifying viable .... Geoelectric/Electromagnetic VLF Survey for. Groundwater in a ...

  1. Exploring pathway interactions in insulin resistant mouse liver

    NARCIS (Netherlands)

    Kelder, T.; Eijssen, L.; Kleemann, R.; Erk, M. van; Kooistra, T.; Evelo, C.

    2011-01-01

    Background: Complex phenotypes such as insulin resistance involve different biological pathways that may interact and influence each other. Interpretation of related experimental data would be facilitated by identifying relevant pathway interactions in the context of the dataset.Results: We

  2. Associations between depressive symptoms and insulin resistance

    DEFF Research Database (Denmark)

    Adriaanse, M C; Dekker, J M; Nijpels, G

    2006-01-01

    AIMS/HYPOTHESIS: The association between depression and insulin resistance has been investigated in only a few studies, with contradictory results reported. The aim of this study was to determine whether the association between symptoms of depression and insulin resistance varies across glucose...... established type 2 diabetes mellitus. Main outcome measures were insulin resistance defined by the homeostasis model assessment for insulin resistance (HOMA-IR) and symptoms of depression using the Centre for Epidemiologic Studies Depression Scale (CES-D). RESULTS: In the total sample, we found a weak.......942). The association between depressive symptoms and insulin resistance was similar for men and women. CONCLUSIONS/INTERPRETATION: We found only weak associations between depressive symptoms and insulin resistance, which did not differ among different glucose metabolism subgroups or between men and women....

  3. Application of Demand-Control Theory to Sign Language Interpreting: Implications for Stress and Interpreter Training.

    Science.gov (United States)

    Dean, Robyn K.; Pollard, Robert Q., Jr.

    2001-01-01

    This article uses the framework of demand-control theory to examine the occupation of sign language interpreting. It discusses the environmental, interpersonal, and intrapersonal demands that impinge on the interpreter's decision latitude and notes the prevalence of cumulative trauma disorders, turnover, and burnout in the interpreting profession.…

  4. Medical interpreters as tools: dangers and challenges in the utilitarian approach to interpreters' roles and functions.

    Science.gov (United States)

    Hsieh, Elaine; Kramer, Eric Mark

    2012-10-01

    This study explores the tensions, challenges, and dangers when a utilitarian view of interpreter is constructed, imposed, and/or reinforced in health care settings. We conducted in-depth interviews and focus groups with 26 medical interpreters from 17 different languages and cultures and 39 providers of five specialties. Grounded theory was used for data analysis. The utilitarian view to interpreters' roles and functions influences providers in the following areas: (a) hierarchical structure and unidirectional communication, (b) the interpreter seen as information gatekeeper, (c) the interpreter seen as provider proxy, and (d) interpreter's emotional support perceived as tools. When interpreters are viewed as passive instruments, a utilitarian approach may compromise the quality of care by silencing patients' and interpreters' voice, objectifying interpreters' emotional work, and exploiting patients' needs. Providers need to recognize that a utilitarian approach to the interpreter's role and functions may create interpersonal and ethical dilemmas that compromise the quality of care. By viewing interpreters as smart technology (rather than passive instruments), both providers and interpreters can learn from and co-evolve with each other, allowing them to maintain control over their expertise and to work as collaborators in providing quality care. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  5. Antibiotic resistance of lactic acid bacteria

    Directory of Open Access Journals (Sweden)

    Bulajić Snežana

    2008-01-01

    Full Text Available Knowledge on the antibiotic resistance of lactic acid bacteria is still limited, possibly because of the large numbers of genera and species encountered in this group, as well as variances in their resistance spectra. The EFSA considers antibiotic resistances, especially transferable resistances, an important decision criterion for determining a strain's QPS status. There are no approved standards for the phenotypic or genotypic evaluation of antibiotic resistances in food isolates. Also, the choice of media is problematic, as well as the specification of MIC breakpoint values as a result of the large species variation and the possible resulting variation in MIC values between species and genera. The current investigations in this field showed that we might end up with a range of different species- or genus-specific breakpoint values that may further increase the current complexity. Another problem associated with safety determinations of starter strains is that once a resistance phenotype and an associated resistance determinant have been identified, it becomes difficult to show that this determinant is not transferable, especially if the resistance gene is not located on a plasmid and no standard protocols for showing genetic transfer are available. Encountering those problems, the QPS system should allow leeway for the interpretations of results, especially when these relate to the methodology for resistance phenotype determinations, determinations of MIC breakpoints for certain genera, species, or strains, the nondeterminability of a genetic basis of a resistance phenotype and the transferability of resistance genes.

  6. Drug resistance

    NARCIS (Netherlands)

    Gorter, J.A.; Potschka, H.; Noebels, J.L.; Avoli, M.; Rogawski, M.A.; Olsen, R.W.; Delgado-Escueta, A.V.

    2012-01-01

    Drug resistance remains to be one of the major challenges in epilepsy therapy. Identification of factors that contribute to therapeutic failure is crucial for future development of novel therapeutic strategies for difficult-to-treat epilepsies. Several clinical studies have shown that high seizure

  7. Integrated interpretation of overlapping AEM datasets achieved through standardisation

    Science.gov (United States)

    Sørensen, Camilla C.; Munday, Tim; Heinson, Graham

    2015-12-01

    Numerous airborne electromagnetic surveys have been acquired in Australia using a variety of systems. It is not uncommon to find two or more surveys covering the same ground, but acquired using different systems and at different times. Being able to combine overlapping datasets and get a spatially coherent resistivity-depth image of the ground can assist geological interpretation, particularly when more subtle geophysical responses are important. Combining resistivity-depth models obtained from the inversion of airborne electromagnetic (AEM) data can be challenging, given differences in system configuration, geometry, flying height and preservation or monitoring of system acquisition parameters such as waveform. In this study, we define and apply an approach to overlapping AEM surveys, acquired by fixed wing and helicopter time domain electromagnetic (EM) systems flown in the vicinity of the Goulds Dam uranium deposit in the Frome Embayment, South Australia, with the aim of mapping the basement geometry and the extent of the Billeroo palaeovalley. Ground EM soundings were used to standardise the AEM data, although results indicated that only data from the REPTEM system needed to be corrected to bring the two surveys into agreement and to achieve coherent spatial resistivity-depth intervals.

  8. A novel methodology for interpreting air quality measurements from urban streets using CFD modelling

    Science.gov (United States)

    Solazzo, Efisio; Vardoulakis, Sotiris; Cai, Xiaoming

    2011-09-01

    In this study, a novel computational fluid dynamics (CFD) based methodology has been developed to interpret long-term averaged measurements of pollutant concentrations collected at roadside locations. The methodology is applied to the analysis of pollutant dispersion in Stratford Road (SR), a busy street canyon in Birmingham (UK), where a one-year sampling campaign was carried out between August 2005 and July 2006. Firstly, a number of dispersion scenarios are defined by combining sets of synoptic wind velocity and direction. Assuming neutral atmospheric stability, CFD simulations are conducted for all the scenarios, by applying the standard k-ɛ turbulence model, with the aim of creating a database of normalised pollutant concentrations at specific locations within the street. Modelled concentration for all wind scenarios were compared with hourly observed NO x data. In order to compare with long-term averaged measurements, a weighted average of the CFD-calculated concentration fields was derived, with the weighting coefficients being proportional to the frequency of each scenario observed during the examined period (either monthly or annually). In summary the methodology consists of (i) identifying the main dispersion scenarios for the street based on wind speed and directions data, (ii) creating a database of CFD-calculated concentration fields for the identified dispersion scenarios, and (iii) combining the CFD results based on the frequency of occurrence of each dispersion scenario during the examined period. The methodology has been applied to calculate monthly and annually averaged benzene concentration at several locations within the street canyon so that a direct comparison with observations could be made. The results of this study indicate that, within the simplifying assumption of non-buoyant flow, CFD modelling can aid understanding of long-term air quality measurements, and help assessing the representativeness of monitoring locations for population

  9. Recognising and Interpreting Named Temporal Expressions

    DEFF Research Database (Denmark)

    Brucato, Matteo; Derczynski, Leon; Llorens, Hectjor

    2013-01-01

    This paper introduces a new class of temporal expression – named temporal expressions – and methods for recognising and interpreting its members. The commonest temporal expressions typically contain date and time words, like April or hours. Research into recognising and interpreting these typical...... expressions is mature in many languages. However, there is a class of expressions that are less typical, very varied, and difficult to automatically interpret. These indicate dates and times, but are harder to detect because they often do not contain time words and are not used frequently enough to appear...

  10. Abstract Interpretation as a Programming Language

    DEFF Research Database (Denmark)

    Rosendahl, Mads

    2013-01-01

    examine different programming styles and ways to represent states. Abstract interpretation is primarily a technique for derivation and specification of program analysis. As with denotational semantics we may also view abstract interpretations as programs and examine the implementation. The main focus...... in this paper is to show that results from higher-order strictness analysis may be used more generally as fixpoint operators for higher-order functions over lattices and thus provide a technique for immediate implementation of a large class of abstract interpretations. Furthermore, it may be seen...

  11. Completed lineament interpretation of the Olkiluoto region

    International Nuclear Information System (INIS)

    Paananen, M.

    2013-10-01

    Site characterization activities at Olkiluoto have been taking place for c. 25 years, including a wide range of different geophysical survey methods using various geometries and scales of investigation. The measurements have been done from the air, ground surface, shallow and deep drillholes and the ONKALO underground facility. As a part of the complementary site investigations, two low-altitude geophysical airborne survey campaigns were done around and at Olkiluoto in 2008 and 2009. The survey in 2008 was focused in the Eurajoensalmi area N or NE of Olkiluoto Island. The survey in 2009 covered most of the Olkiluoto Island, the neighbouring sea area and the archipelago W, SW and S of Olkiluoto as well as some of the mainland area SE of Olkiluoto. This report presents a new lineament interpretation based on these new geophysical airborne surveys. For the interpretation work, the data were extensively further processed into different gradients and filtered data sets and maps. Furthermore, the potential of automatic curvature analyses was examined. Also, quantitative profile interpretation was done from a number of profiles to find out the dips and exact locations of the contacts of some features. The qualitative interpretation of the lineaments was carried out by visually inspecting the different versions of the geophysical maps and by digitizing the geometry of each interpreted lineament. The lineaments are collated into two ArcGIS themes (one for magnetic and one for EM lineaments), accompanied by an attribute table that includes a number of attributes for each interpreted feature: lineament identifier, reference to the data used in interpretation, uncertainty, length, average orientation and probable geological character. The total number of new interpreted features is 125 magnetic and 33 electromagnetic lineaments. The main trend of the interpreted features varies between WNW-ESE and NNW-SSE. Furthermore, trends in directions almost N-S and E-W are also

  12. Completed lineament interpretation of the Olkiluoto region

    Energy Technology Data Exchange (ETDEWEB)

    Paananen, M. [Geological Survey of Finland, Espoo (Finland)

    2013-10-15

    Site characterization activities at Olkiluoto have been taking place for c. 25 years, including a wide range of different geophysical survey methods using various geometries and scales of investigation. The measurements have been done from the air, ground surface, shallow and deep drillholes and the ONKALO underground facility. As a part of the complementary site investigations, two low-altitude geophysical airborne survey campaigns were done around and at Olkiluoto in 2008 and 2009. The survey in 2008 was focused in the Eurajoensalmi area N or NE of Olkiluoto Island. The survey in 2009 covered most of the Olkiluoto Island, the neighbouring sea area and the archipelago W, SW and S of Olkiluoto as well as some of the mainland area SE of Olkiluoto. This report presents a new lineament interpretation based on these new geophysical airborne surveys. For the interpretation work, the data were extensively further processed into different gradients and filtered data sets and maps. Furthermore, the potential of automatic curvature analyses was examined. Also, quantitative profile interpretation was done from a number of profiles to find out the dips and exact locations of the contacts of some features. The qualitative interpretation of the lineaments was carried out by visually inspecting the different versions of the geophysical maps and by digitizing the geometry of each interpreted lineament. The lineaments are collated into two ArcGIS themes (one for magnetic and one for EM lineaments), accompanied by an attribute table that includes a number of attributes for each interpreted feature: lineament identifier, reference to the data used in interpretation, uncertainty, length, average orientation and probable geological character. The total number of new interpreted features is 125 magnetic and 33 electromagnetic lineaments. The main trend of the interpreted features varies between WNW-ESE and NNW-SSE. Furthermore, trends in directions almost N-S and E-W are also

  13. 3D quantitative interpretation of archaeo-magnetic data: Adaptation of aero-magnetic interpretation techniques for archaeological purposes

    Science.gov (United States)

    Cheyney, S.; Hill, I. A.; Linford, N.; Fishwick, S.; Leech, C.

    2011-12-01

    information from Euler deconvolution can also be obtained, but is highly dependent on selecting an appropriate structural index. We demonstrate that results from both the edge-detection methods and Euler deconvolution can be used to constrain an inversion. Such results can be determined simply, automatically and objectively using few user-derived assumptions or constraints. Initial estimates of subsurface structure can then used to create an initial reference model, or to constrain the depth weighting of the inversion. This increases confidence in the final result. Greater interpretation of the magnetic data will aid the planning of higher resolution surveys such as GPR or resistivity, or to position targeted excavations. In some situations the detailed 3D geophysical model may supply sufficient archaeological information to avoid excavation, thus reducing cost and risk to the archaeological material.

  14. On the Dogmatics of Contract Interpretation

    Institute of Scientific and Technical Information of China (English)

    Yang Guoqing

    2017-01-01

    The interpretation of contract has attracted much attention in the practice of contract law and the basic problems to be solved are what the parties agree on and how to set up the rules of adjudication. The present domestic studies are not conducive to contract prac-tices because they either unnecessarily elevate scientific problems to the speculative realm of fantasy, or make the problems become more unreal and abstract. The two traditional theories of contract interpretation do not conflict in values in terms of the autonomy of the will and trust protection. However, in today' s society where cultural pluralism and legal value plural-ism exist, because of different contract practices, differentiation and individualization of con-tract interpretation will become the basic patterns. Therefore, it is impossible and unnecessary to construct a unitary model, but it is of great significance to introduce the dogmatics-orien-ted contract interpretation.

  15. The interpretation and management of thyroid disorders

    African Journals Online (AJOL)

    population reference range, will induce very pronounced TSH changes. ... An overview of the management of ... The interpretation and management of thyroid disorders ..... Tietz textbook of clinical cemistry and molecular diagnostics. 4th ed.

  16. Computerised Analysis, Interpretation, Storage and Retrieval of ...

    African Journals Online (AJOL)

    1974-06-08

    Jun 8, 1974 ... research. This whole process is time-consuming for both tech- nicians and ... ECG directly from the patient, make an automatic graphic recording on ..... reasoned that the electrocardiographic interpretation is better done by a ...

  17. Geometric interpretation of density displacements and charge ...

    Indian Academy of Sciences (India)

    Unknown

    The “geometric” interpretation of the electronic density displacements in the Hilbert space is ... an attitude is also close to the chemical thinking ..... These vectors explicitly define the corresponding ..... chain-rule for implicit functionals: p p. N p.

  18. Pattern recognition approach to data interpretation

    National Research Council Canada - National Science Library

    Wolff, Diane D; Parsons, M. L

    1983-01-01

    An attempt is made in this book to give scientists a detailed working knowledge of the powerful mathematical tools available to aid in data interpretation, especially when confronted with large data...

  19. The Status of Interpreters for Deaf Canadians.

    Science.gov (United States)

    Schein, Jerome D.; Yarwood, Sara

    1990-01-01

    A national survey of 170 interpreters for deaf Canadians examined demographic characteristics; knowledge of sign; education; experience; employment; voluntary service; clients served; settings; earnings and fees; and opinions regarding their work, compensation, working conditions, ethics, and education. (JDD)

  20. Abstract Interpretation as a Programming Language

    Directory of Open Access Journals (Sweden)

    Mads Rosendahl

    2013-09-01

    Full Text Available In David Schmidt's PhD work he explored the use of denotational semantics as a programming language. It was part of an effort to not only treat formal semantics as specifications but also as interpreters and input to compiler generators. The semantics itself can be seen as a program and one may examine different programming styles and ways to represent states. Abstract interpretation is primarily a technique for derivation and specification of program analysis. As with denotational semantics we may also view abstract interpretations as programs and examine the implementation. The main focus in this paper is to show that results from higher-order strictness analysis may be used more generally as fixpoint operators for higher-order functions over lattices and thus provide a technique for immediate implementation of a large class of abstract interpretations. Furthermore, it may be seen as a programming paradigm and be used to write programs in a circular style.

  1. Interpretation of aluminum-alloy weld radiography

    Science.gov (United States)

    Duren, P. C.; Risch, E. R.

    1971-01-01

    Report proposes radiographic terminology standardization which allows scientific interpretation of radiographic films to replace dependence on individual judgement and experience. Report includes over 50 photographic pages where radiographs of aluminum welds with defects are compared with prepared weld sections photomacrographs.

  2. Interpretation of growth hormone provocative tests

    DEFF Research Database (Denmark)

    Andersson, A M; Orskov, H; Ranke, M B

    1995-01-01

    To compare interpretations of growth hormone (GH) provocative tests in laboratories using six different GH immunoassays (one enzymeimmunometric assay (EIMA, assay 1), one immunoradiometric assay (IRMA, assay 5), one time-resolved fluorimmunometric assay (TRFIA, assay 3) and three radioimmunoassays...

  3. Interpreters' notes. On the choice of language

    DEFF Research Database (Denmark)

    Dam, Helle Vrønning

    2004-01-01

    This paper reports on a small-scale empirical study on note-taking in consecutive interpreting. As data, the study draws on the notes produced by four subjects while interpreting one Spanish source text consecutively into Danish, on the one hand, and one Danish source text into Spanish...... to particular scrutiny here. However, somewhat surprisingly, the results of the analyses indicate that the choice of language in note-taking is governed mainly by the status of the language in the interpreters' language combination, i.e. whether it is an A- or a B-language, and much less by its status......, on the other. The aim of the study is to explore what governs conference interpreters' choice of language for their notes. The categories traditionally used to discuss, describe and explain this choice are those of 'source language' and 'target language', and these categories are therefore subject...

  4. Clinical Utility of Blood Cell Histogram Interpretation.

    Science.gov (United States)

    Thomas, E T Arun; Bhagya, S; Majeed, Abdul

    2017-09-01

    An automated haematology analyser provides blood cell histograms by plotting the sizes of different blood cells on X-axis and their relative number on Y-axis. Histogram interpretation needs careful analysis of Red Blood Cell (RBC), White Blood Cell (WBC) and platelet distribution curves. Histogram analysis is often a neglected part of the automated haemogram which if interpreted well, has significant potential to provide diagnostically relevant information even before higher level investigations are ordered.

  5. Computerized Interpretation of Dynamic Breast MRI

    Science.gov (United States)

    2005-05-01

    The interpretation criteria in the current literature fall Breast MRI has emerged as a promising modality for the into two major categories: 5’ 14...is that theraphy , current interpretation schemes might not be sufficiently ro- Despite its well-recognized advantages, applications of bust. MRI in...postcontrast series For the manual delineation, a radiologist (U.B.), blinded were then taken with a time interval of 60 s. Each series to the histological

  6. NODAL interpreter for CP/M

    International Nuclear Information System (INIS)

    Oide, Katsunobu.

    1982-11-01

    A NODAL interpreter which works under CP/M operating system is made for microcomputers. This interpreter language named NODAL-80 has a similar structure to the NODAL of SPS, but its commands, variables, and expressions are modified to increase the flexibility of programming. NODAL-80 also uses a simple intermediate code to make the execution speed fast without imposing any restriction on the dynamic feature of NODAL language. (author)

  7. Radiology Residents' Performance in Screening Mammography Interpretation

    International Nuclear Information System (INIS)

    Lee, Eun Hye; Lyou, Chae Yeon

    2013-01-01

    To evaluate radiology residents' performance in screening mammography interpretation and to analyze the factors affecting performance. We enrolled 203 residents from 21 institutions and performed mammography interpretation tests. Between the trainee and non-trainee groups, we compared the interpretation score, recall rate, sensitivity, positive predictive value (PPV) and false-positive rate (FPR). We estimated the training effect using the score differences between trainee and non-trainee groups. We analyzed the factors affecting performance between training-effective and non-effective groups. Trainees were superior to non-trainees regarding interpretation score (43.1 vs. 37.1), recall rate (11.0 vs. 15.5%), sensitivity (83.6 vs. 72.0%), PPV (53.0 vs. 32.4%) and FPR (13.5 vs. 25.5). The longer the training period, the better were the interpretation score, recall rate, sensitivity, PPV and FPR (rho = 0.486, -0.375, 0.343, 0.504, -0.446, respectively). The training affected an increase by an average of 6 points; however, 31.6% of institutions showed no effect. A difference was noted in the volume of mammography interpretation during a month (594.0 vs. 476.9) and dedication of breast staff (61.5 vs. 0%) between training-effective and non-effective groups. Trainees showed better performance in mammography interpretation compared to non-trainees. Moreover, performance was correlated with the training period. The factors affecting performance were the volume of mammography interpretation and the dedication of the breast staff.

  8. Comparison of the CoaguChek XS handheld coagulation analyzer and conventional laboratory methods measuring international normalised ratio (INR) values during the time to therapeutic range after mechanical valve surgery.

    Science.gov (United States)

    Bardakci, Hasmet; Altıntaş, Garip; Çiçek, Omer Faruk; Kervan, Umit; Yilmaz, Sevinc; Kaplan, Sadi; Birincioglu, Cemal Levent

    2013-05-01

    To compare the international normalised ratio (INR) value of patients evaluated using the CoaguChek XS versus conventional laboratory methods, in the period after open-heart surgery for mechanical valve replacement until a therapeutic range is achieved using vitamin K antagonists (VKA) together with low molecular weight heparin (LMWH). One hundred and five patients undergoing open-heart surgery for mechanical valve replacement were enrolled. Blood samples were collected from patients before surgery, and on the second and fifth postoperative days, simultaneously for both the point of care device and conventional laboratory techniques. Patients were administered VKA together with LMWH at therapeutic doses (enoxaparin 100 IU/kg twice daily) subcutaneously, until an effective range was achieved on approximately the fifth day after surgery. The mean INR values using the CoaguChek XS preoperatively and on the second and fifth days postoperatively were 1.20 (SD ± 0.09), 1.82 (SD ± 0.45), and 2.55 (SD ± 0.55), respectively. Corresponding results obtained using conventional laboratory techniques were 1.18 (SD ± 0.1), 1.81 (SD ± 0.43), and 2.51 (SD ± 0.58). The correlation coefficient was r = 0.77 preoperatively, r = 0.981 on postoperative day 2, and r = 0.983 on postoperative day 5. Results using the CoaguChek XS Handheld Coagulation Analyzer correlated strongly with conventional laboratory methods, in the bridging period between open-heart surgery for mechanical valve replacement and the achievement of a therapeutic range on warfarin and LMWH. © 2013 Wiley Periodicals, Inc.

  9. Factors associated with failure to correct the international normalised ratio following fresh frozen plasma administration among patients treated for warfarin-related major bleeding. An analysis of electronic health records.

    Science.gov (United States)

    Menzin, J; White, L A; Friedman, M; Nichols, C; Menzin, J; Hoesche, J; Bergman, G E; Jones, C

    2012-04-01

    This study assessed the frequency and factors associated with failure to correct international normalised ratio (INR) in patients administered fresh frozen plasma (FFP) for warfarin-related major bleeding. This retrospective database analysis used electronic health records from an integrated health system. Patients who received FFP between 01/01/2004 and 01/31/2010, and who met the following criteria were selected: major haemorrhage diagnosis the day before to the day after initial FFP administration; INR ≥2 on the day before or the day of FFP and another INR result available; warfarin prescription within 90 days. INR correction (defined as INR ≤1.3) was evaluated at the last available test up to one day following FFP. A total of 414 patients met selection criteria (mean age 75 years, 53% male, mean Charlson score 2.5). Patients presented with gastrointestinal bleeding (58%), intracranial haemorrhage (38%) and other bleed types (4%). The INR of 67% of patients remained uncorrected at the last available test up to one day following receipt of FFP. In logistic regression analysis, the INR of patients who were older, those with a Charlson score of 4 or greater, and those with non-ICH bleeds (odds ratio vs. intracranial bleeding 0.48; 95% confidence interval 0.31-0.76) were more likely to remain uncorrected within one day following FFP administration. In an alternative definition of correction, (INR ≤1.5), 39% of patients' INRs remained uncorrected. For a substantial proportion of patients, the INRs remain inadequately or uncorrected following FFP administration, with estimates varying depending on the INR threshold used.

  10. Maternal supplementation with conjugated linoleic acid in the setting of diet-induced obesity normalises the inflammatory phenotype in mothers and reverses metabolic dysfunction and impaired insulin sensitivity in offspring.

    Science.gov (United States)

    Segovia, Stephanie A; Vickers, Mark H; Zhang, Xiaoyuan D; Gray, Clint; Reynolds, Clare M

    2015-12-01

    Maternal consumption of a high-fat diet significantly impacts the fetal environment and predisposes offspring to obesity and metabolic dysfunction during adulthood. We examined the effects of a high-fat diet during pregnancy and lactation on metabolic and inflammatory profiles and whether maternal supplementation with the anti-inflammatory lipid conjugated linoleic acid (CLA) could have beneficial effects on mothers and offspring. Sprague-Dawley rats were fed a control (CD; 10% kcal from fat), CLA (CLA; 10% kcal from fat, 1% total fat as CLA), high-fat (HF; 45% kcal from fat) or high fat with CLA (HFCLA; 45% kcal from fat, 1% total fat as CLA) diet ad libitum 10days prior to and throughout gestation and lactation. Dams and offspring were culled at either late gestation (fetal day 20, F20) or early postweaning (postnatal day 24, P24). CLA, HF and HFCLA dams were heavier than CD throughout gestation. Plasma concentrations of proinflammatory cytokines interleukin-1β and tumour necrosis factor-α were elevated in HF dams, with restoration in HFCLA dams. Male and female fetuses from HF dams were smaller at F20 but displayed catch-up growth and impaired insulin sensitivity at P24, which was reversed in HFCLA offspring. HFCLA dams at P24 were protected from impaired insulin sensitivity as compared to HF dams. Maternal CLA supplementation normalised inflammation associated with consumption of a high-fat diet and reversed associated programming of metabolic dysfunction in offspring. This demonstrates that there are critical windows of developmental plasticity in which the effects of an adverse early-life environment can be reversed by maternal dietary interventions. Copyright © 2015 Elsevier Inc. All rights reserved.

  11. An additional bolus of rapid-acting insulin to normalise postprandial cardiovascular risk factors following a high-carbohydrate high-fat meal in patients with type 1 diabetes: A randomised controlled trial.

    Science.gov (United States)

    Campbell, Matthew D; Walker, Mark; Ajjan, Ramzi A; Birch, Karen M; Gonzalez, Javier T; West, Daniel J

    2017-07-01

    To evaluate an additional rapid-acting insulin bolus on postprandial lipaemia, inflammation and pro-coagulation following high-carbohydrate high-fat feeding in people with type 1 diabetes. A total of 10 males with type 1 diabetes [HbA 1c 52.5 ± 5.9 mmol/mol (7.0% ± 0.5%)] underwent three conditions: (1) a low-fat (LF) meal with normal bolus insulin, (2), a high-fat (HF) meal with normal bolus insulin and (3) a high-fat meal with normal bolus insulin with an additional 30% insulin bolus administered 3-h post-meal (HFA). Meals had identical carbohydrate and protein content and bolus insulin dose determined by carbohydrate-counting. Blood was sampled periodically for 6-h post-meal and analysed for triglyceride, non-esterified-fatty acids, apolipoprotein B48, glucagon, tumour necrosis factor alpha, fibrinogen, human tissue factor activity and plasminogen activator inhibitor-1. Continuous glucose monitoring captured interstitial glucose responses. Triglyceride concentrations following LF remained similar to baseline, whereas triglyceride levels following HF were significantly greater throughout the 6-h observation period. The additional insulin bolus (HFA) normalised triglyceride similarly to low fat 3-6 h following the meal. HF was associated with late postprandial elevations in tumour necrosis factor alpha, whereas LF and HFA was not. Fibrinogen, plasminogen activator inhibitor-1 and tissue factor pathway levels were similar between conditions. Additional bolus insulin 3 h following a high-carbohydrate high-fat meal prevents late rises in postprandial triglycerides and tumour necrosis factor alpha, thus improving cardiovascular risk profile.

  12. Cling - The LLVM-based C++ Interpreter

    CERN Multimedia

    CERN. Geneva

    2012-01-01

    Cling (http://cern.ch/cling) is a C++ interpreter, built on top of clang (http://clang.llvm.org) and LLVM (http://llvm.org). Like its predecessor CINT, cling offers an interactive, terminal-like prompt. It enables exploratory programming with rapid edit / run cycles. The ROOT team has more than 15 years of experience with C++ interpreters, and this has been fully exploited in the design of cling. However, matching the concepts of an interpreter to a compiler library is a non-trivial task; we will explain how this is done for cling, and how we managed to implement cling as a small (10,000 lines of code) extension to the clang and llvm libraries. The resulting features clearly show the advantages of basing an interpreter on a compiler. Cling uses clang's praised concise and easy to understand diagnostics. Building an interpreter on top of a compiler library makes the transition between interpreted and compiled code much easier and smoother. We will present the design, e.g. how cling treats the C++ extensions ...

  13. Alternative psychosis (forced normalisation) in epilepsy

    African Journals Online (AJOL)

    changed, this should always be considered as a potential cause of a new or ... psychosis with thought disorder, delusions, hallucinations. • significant .... On mental status examination, the patient's behaviour was .... appeared for the first time.

  14. Alternative psychosis (forced normalisation in epilepsy

    Directory of Open Access Journals (Sweden)

    Vongani Titi Raymond Ntsanwisi

    2011-06-01

    Full Text Available Abstract Forced normalization is a paradoxical relationship between seizure activity and behavioural problems. A 20 year old male with recurrent refractory tonic clonic epilepsy experienced forced normalization, whilst on medication with multiple anti- epileptic drugs (AEDs.(Valproate Sodium, Carbamazepine, and Topiramate. A reduction in the seizure burden correlated with sudden behavioural changes manifesting with aggressive outbursts and violence.. The present case may help clarify the mechanism of forced normalization whilst providing some helpful hints regarding the diagnosis and treatment of symptoms observed in recurrent refractory seizures.

  15. Animation of Antimicrobial Resistance

    Medline Plus

    Full Text Available ... video) Animation of Antimicrobial Resistance (text version) Arabic Translation of Animation of Antimicrobial Resistance Chinese Translation of Animation of Antimicrobial Resistance French Translation of ...

  16. Nuclear arbitration: Interpreting non-proliferation agreements

    International Nuclear Information System (INIS)

    Tzeng, Peter

    2015-01-01

    At the core of the nuclear non-proliferation regime lie international agreements. These agreements include, inter alia, the Nuclear Non-proliferation Treaty, nuclear co-operation agreements and nuclear export control agreements.1 States, however, do not always comply with their obligations under these agreements. In response, commentators have proposed various enforcement mechanisms to promote compliance. The inconvenient truth, however, is that states are generally unwilling to consent to enforcement mechanisms concerning issues as critical to national security as nuclear non-proliferation.3 This article suggests an alternative solution to the non-compliance problem: interpretation mechanisms. Although an interpretation mechanism does not have the teeth of an enforcement mechanism, it can induce compliance by providing an authoritative interpretation of a legal obligation. Interpretation mechanisms would help solve the non-compliance problem because, as this article shows, in many cases of alleged non-compliance with a non-proliferation agreement, the fundamental problem has been the lack of an authoritative interpretation of the agreement, not the lack of an enforcement mechanism. Specifically, this article proposes arbitration as the proper interpretation mechanism for non-proliferation agreements. It advocates the establishment of a 'Nuclear Arbitration Centre' as an independent branch of the International Atomic Energy Agency (IAEA), and recommends the gradual introduction of arbitration clauses into the texts of non-proliferation agreements. Section I begins with a discussion of international agreements in general and the importance of interpretation and enforcement mechanisms. Section II then discusses nuclear non-proliferation agreements and their lack of interpretation and enforcement mechanisms. Section III examines seven case studies of alleged non-compliance with non-proliferation agreements in order to show that the main problem in many cases

  17. A resistor interpretation of general anisotropic cardiac tissue.

    Science.gov (United States)

    Shao, Hai; Sampson, Kevin J; Pormann, John B; Rose, Donald J; Henriquez, Craig S

    2004-02-01

    This paper describes a spatial discretization scheme for partial differential equation systems that contain anisotropic diffusion. The discretization method uses unstructured finite volumes, or the boxes, that are formed as a secondary geometric structure from an underlying triangular mesh. We show how the discretization can be interpreted as a resistive circuit network, where each resistor is assigned at each edge of the triangular element. The resistor is computed as an anisotropy dependent geometric quantity of the local mesh structure. Finally, we show that under certain conditions, the discretization gives rise to negative resistors that can produce non-physical hyperpolarizations near depolarizing stimuli. We discuss how the proper choice of triangulation (anisotropic Delaunay triangulation) can ensure monotonicity (i.e. all resistors are positive).

  18. Interpreting cost of ownership for mix-and-match lithography

    Science.gov (United States)

    Levine, Alan L.; Bergendahl, Albert S.

    1994-05-01

    Cost of ownership modeling is a critical and emerging tool that provides significant insight into the ways to optimize device manufacturing costs. The development of a model to deal with a particular application, mix-and-match lithography, was performed in order to determine the level of cost savings and the optimum ways to create these savings. The use of sensitivity analysis with cost of ownership allows the user to make accurate trade-offs between technology and cost. The use and interpretation of the model results are described in this paper. Parameters analyzed include several manufacturing considerations -- depreciation, maintenance, engineering and operator labor, floorspace, resist, consumables and reticles. Inherent in this study is the ability to customize this analysis for a particular operating environment. Results demonstrate the clear advantages of a mix-and-match approach for three different operating environments. These case studies also demonstrate various methods to efficiently optimize cost savings strategies.

  19. Risk factors associated with fluoroquinolone-resistant enterococcal urinary tract infections in a tertiary care university hospital in north India

    Directory of Open Access Journals (Sweden)

    Tuhina Banerjee

    2016-01-01

    Interpretation & conclusions: Our results showed that fluoroquinolone resistance in enterococcal UTI was largely associated with indoor usage of antibiotics and use of indwelling devices. Knowledge of risk factors is important to curb this emergence of resistance.

  20. Animation of Antimicrobial Resistance

    Medline Plus

    Full Text Available ... Animal & Veterinary Safety & Health Antimicrobial Resistance Animation of Antimicrobial Resistance Share Tweet Linkedin Pin it More sharing options ... of Animation of Antimicrobial Resistance More in Antimicrobial ... Antimicrobial Resistance Monitoring System About NARMS 2015 NARMS Integrated ...

  1. DIFFICULTY OF AMENDMENT AND INTERPRETATIVE CHOICE

    Directory of Open Access Journals (Sweden)

    Andrew Coan

    2016-01-01

    Full Text Available The extreme difficulty of amending the U.S. Constitution plays a central but largely unexamined role in theoretical debates over interpretive choice. In particular, conventional wisdom assumes that the extreme difficulty of Article V amendment weakens the case for originalism. This view might ultimately be correct, but it is not the freestanding argument against originalism it is often presumed to be. Rather, it depends on contestable normative and empirical premises that require defense. If those premises are wrong, the stringency of Article V might actually strengthen the case for originalism. Or Article V might have no impact on that case one way or another. This “complexity thesis” highlights and clarifies the role that difficulty of amendment plays across a range of significant interpretive debates, including those surrounding writtenness, John Hart Ely’s representation-reinforcement theory, interpretive pluralism, and originalism as a theory of positive law. It also has important implications for the under-studied relations between statutory and constitutional interpretation and federal and state constitutional interpretation.

  2. Analysis of Visual Interpretation of Satellite Data

    Science.gov (United States)

    Svatonova, H.

    2016-06-01

    Millions of people of all ages and expertise are using satellite and aerial data as an important input for their work in many different fields. Satellite data are also gradually finding a new place in education, especially in the fields of geography and in environmental issues. The article presents the results of an extensive research in the area of visual interpretation of image data carried out in the years 2013 - 2015 in the Czech Republic. The research was aimed at comparing the success rate of the interpretation of satellite data in relation to a) the substrates (to the selected colourfulness, the type of depicted landscape or special elements in the landscape) and b) to selected characteristics of users (expertise, gender, age). The results of the research showed that (1) false colour images have a slightly higher percentage of successful interpretation than natural colour images, (2) colourfulness of an element expected or rehearsed by the user (regardless of the real natural colour) increases the success rate of identifying the element (3) experts are faster in interpreting visual data than non-experts, with the same degree of accuracy of solving the task, and (4) men and women are equally successful in the interpretation of visual image data.

  3. Use of interpreters in individual psychotherapy.

    Science.gov (United States)

    Baxter, H; Cheng, L Y

    1996-02-01

    This paper was written after one of the authors treated a case by individual therapy using an interpreter, as patient and therapist spoke different languages. There is little literature on this subject, and this paper describes our findings and recommendations for using this approach. A 15-year-old Chinese, Cantonese-speaking in-patient in Hong Kong was treated with individual psychodynamic psychotherapy by an English-speaking Caucasian psychotherapist. The Chinese interpreter attended each session, and therapy was supervised by a bilingual Chinese supervisor. The alternative was to not carry out any therapy, as there was no other therapist available. The patient was treated for a total of 32 sessions. Issues involving language and culture differences between therapist and patient, issues of therapy in a triadic situation involving group dynamics, and specific therapy difficulties raised by the presence of the interpreter are discussed. Therapy was not as effective as hoped, but the patient made some improvements. Finding a suitable interpreter is difficult and their role must be well defined. A bilingual supervisor is also needed to monitor the translation as well as supervising the therapist. Psychotherapy through an interpreter is feasible but not ideal.

  4. Interpreters' notes. On the choice of language

    DEFF Research Database (Denmark)

    Dam, Helle Vrønning

    2004-01-01

    This paper reports on a small-scale empirical study on note-taking in consecutive interpreting. As data, the study draws on the notes produced by four subjects while interpreting one Spanish source text consecutively into Danish, on the one hand, and one Danish source text into Spanish, on the ot...... in the interpreting task, i.e. whether it functions as the source or the target language. Drawing on the concept of processing capacity and the Effort Model of consecutive, a tentative explanation of these findings is suggested......., on the other. The aim of the study is to explore what governs conference interpreters' choice of language for their notes. The categories traditionally used to discuss, describe and explain this choice are those of 'source language' and 'target language', and these categories are therefore subject...... to particular scrutiny here. However, somewhat surprisingly, the results of the analyses indicate that the choice of language in note-taking is governed mainly by the status of the language in the interpreters' language combination, i.e. whether it is an A- or a B-language, and much less by its status...

  5. ANALYSIS OF VISUAL INTERPRETATION OF SATELLITE DATA

    Directory of Open Access Journals (Sweden)

    H. Svatonova

    2016-06-01

    Full Text Available Millions of people of all ages and expertise are using satellite and aerial data as an important input for their work in many different fields. Satellite data are also gradually finding a new place in education, especially in the fields of geography and in environmental issues. The article presents the results of an extensive research in the area of visual interpretation of image data carried out in the years 2013 - 2015 in the Czech Republic. The research was aimed at comparing the success rate of the interpretation of satellite data in relation to a the substrates (to the selected colourfulness, the type of depicted landscape or special elements in the landscape and b to selected characteristics of users (expertise, gender, age. The results of the research showed that (1 false colour images have a slightly higher percentage of successful interpretation than natural colour images, (2 colourfulness of an element expected or rehearsed by the user (regardless of the real natural colour increases the success rate of identifying the element (3 experts are faster in interpreting visual data than non-experts, with the same degree of accuracy of solving the task, and (4 men and women are equally successful in the interpretation of visual image data.

  6. From Copenhagen to Neo-Copenhagen Interpretation

    Science.gov (United States)

    de Muynck, Willem M.

    2007-12-01

    Positive and negative features of the Copenhagen interpretation are discussed. As positive features can be mentioned its pragmatism and its awareness of the crucial role of measurement. However, the main part of the contribution is devoted to the negative features, to wit, its pragmatism (once again), its confounding of preparation and measurement, its classical account of measurement, its completeness claims, the ambiguity of its notion of correspondence, its confused notion of complementarity. It is demonstrated how confusions and paradoxes stemming from the negative features of the Copenhagen interpretation can be dealt with in an amended interpretation, to be referred to as `neo-Copenhagen interpretation', in which the role of the measuring instrument is taken seriously by recognizing the quantum mechanical character of its interaction with the microscopic object. The ensuing necessity of extending the notion of a quantum mechanical observable from the Hermitian operator of the standard formalism to the positive operator-valued measure of a generalized formalism yields a sound mathematical basis for a transition from the Copenhagen contextualistic-realist interpretation to the neo-Copenhagen empiricist one. Applications to the uncertainty relations and to the Bell inequalities are briefly discussed.

  7. Insulin Resistance

    DEFF Research Database (Denmark)

    Jensen, Benjamin Anderschou Holbech

    Insulin resistance (IR) is escalating with alarming pace and is no longer restricted to westernized countries. As a forerunner for some of the most serious threats to human health including metabolic syndrome, cardiovascular diseases, and type 2-diabetes, the need for new treatment modalities...... interventions. We further show that improving the inflammatory toning, using fish oil as fat source, protects mice against diet induced obesity and -inflammation while preserving insulin sensitivity, even in the absence of free fatty acid receptor 4. Conversely, HFD-induced intestinal dysbiosis is associated...

  8. Interpretation of self-potential data for dam seepage investigations

    Energy Technology Data Exchange (ETDEWEB)

    Corwin, R.F.; Sheffer, M.R.; Salmon, G. [BC Hydro, Burnaby, BC (Canada)

    2007-04-15

    This book represents one of a series on the subject of geophysical methods and their use in assessing seepage and internal erosion in embankment dams. This manual facilitates the interpretation of self-potential (SP) data generated by subsurface fluid flow, with an emphasis on dam seepage studies. It is intended for users with a background in geophysics or engineering having a general familiarity with both the SP and direct-current (DC) resistivity methods and their applications. It includes an extensive reference list covering all aspects of available SP interpretation techniques, including qualitative, analytical and numerical methods. Particular emphasis is placed on the use of geometric source analytical modeling methods to evaluate SP anomalies. These methods provide a simple yet efficient means of estimating the location and depth of current sources of observed SP data, which may be linked to fluid flow in the subsurface. The manual is primarily oriented toward embankment dams and earthen structures such as levees and dikes. SP methods have been used to investigate seepage through pervious zones and cracks in concrete and concrete-faced structures. The manual describes the nature of SP fields generated by both uniform and non-uniform dam seepage flow, as well as non-seepage sources of SP variations. These methods enable the study of more complex systems and require a more comprehensive analysis of a given field site. refs., tabs., figs.

  9. Effects of resistive bodies on DC electrical soundings

    Directory of Open Access Journals (Sweden)

    L. Alfano

    1996-06-01

    Full Text Available Some deep DC electrical soundings, performed in alpine and apenninic areas with the continuous polar dipole-dipole spread, show apparent resistivity curves with positive slopes. Measured values of apparent resistivity reach 30000 Wm. Applying the "surface charges" method we developed three dimensional mathematical models, by means of which we can state simple rules for determining the minimum extensions of the deep resistive bodies, fundamental information for a more precise interpretation of the field results.

  10. A consistent interpretation of quantum mechanics

    International Nuclear Information System (INIS)

    Omnes, Roland

    1990-01-01

    Some mostly recent theoretical and mathematical advances can be linked together to yield a new consistent interpretation of quantum mechanics. It relies upon a unique and universal interpretative rule of a logical character which is based upon Griffiths consistent history. Some new results in semi-classical physics allow classical physics to be derived from this rule, including its logical aspects, and to prove accordingly the existence of determinism within the quantum framework. Together with decoherence, this can be used to retrieve the existence of facts, despite the probabilistic character of the theory. Measurement theory can then be made entirely deductive. It is accordingly found that wave packet reduction is a logical property, whereas one can always choose to avoid using it. The practical consequences of this interpretation are most often in agreement with the Copenhagen formulation but they can be proved never to give rise to any logical inconsistency or paradox. (author)

  11. Schroedinger and the interpretation of quantum mechanics

    International Nuclear Information System (INIS)

    Rohrlich, F.

    1987-01-01

    On the occasion of the centennial of his birth, Schroedinger's life and views are sketched and his critique of the interpretation of quantum mechanics accepted at his time is examined. His own interpretation, which he had to abandon after a short time, provides a prime example of the way in which the tentative meaning of central theoretical terms in a new and revolutionary theory often fails. Schroedinger's strong philosophical convictions have played a key role in his refusal to break with many of the notions of classical physics. At the same time, they made him into a keen and incisive critic of the Copenhagen interpretation. His criticism is compared with present views on quantum mechanics

  12. The EMU debt criterion: an interpretation

    Directory of Open Access Journals (Sweden)

    R. BERNDSEN

    1997-12-01

    Full Text Available The convergence criteria specified in the Maastricht Treaty on government deficit and debt, inflation, the exchange rate and the long-term interest rate will play an important, if not decisive, role in determining which countries move on to the third stage of the Economic and Monetary Union (EMU. The aim of this work is to provide a possible interpretation of the EMU debt criterion. The author investigates the government debt criterion which, as Article 104c(2b of the Treaty shows, has a considerable scope for interpretation. Although this subject has been discussed extensively, relatively little work has been done to develop a clear interpretation of the EMU debt criterion. A flexible approach is adopted in which parts of the relevant Treaty text are characterised using two parameters.

  13. Formalism and physical interpretation in Schroedinger

    International Nuclear Information System (INIS)

    Paty, M.

    1992-01-01

    The question of the relation between a formalism and its physical interpretation arises not only when theoretical and conceptual systems are reorganized, but in the theoretical elaboration as well. The Schroedinger's work and thought are examined in this paper with this double concern. His work on the mathematical formalism is constantly sustained by a proper physical thought which takes the form of a wave intuition that guarantees him intelligibility. Concerning his interpretation of quantum mechanics, his thought remains characterized, through its evolution, by a w ave image of the world . The way he deals with space-time structure in General Relativity and favours the possibility of a direct interpretation of space-time geometrical quantities, is also studied. (author). 75 refs

  14. Designing for collaborative interpretation in telemonitoring

    DEFF Research Database (Denmark)

    Andersen, Tariq Osman; Bjørn, Pernille; Kensing, Finn

    2011-01-01

    with a design interventionist perspective was conducted to investigate the telemonitoring arrangement for chronic heart patients with ICDs and to identify the nature of the collaborative practices involved in ICD data interpretation. We diagnose the main challenges involved in collaborative interpretation...... practices. These insights were used to re-design the socio-technical setup of the telemonitoring practices by designing and building a web-based, patient-centric, collaborative application, myRecord, to re-introduce the patients as active participants into the telemonitoring setup. Finally, we introduce my......Record at Copenhagen University Hospital and evaluate the new practices and the collaborative technology related to the transformed role of the patients. Results: The interpretation of ICD data is a collaborative practice engaging clinicians and patients and involving three separate collaborative processes...

  15. Interpreting Results from the Multinomial Logit Model

    DEFF Research Database (Denmark)

    Wulff, Jesper

    2015-01-01

    This article provides guidelines and illustrates practical steps necessary for an analysis of results from the multinomial logit model (MLM). The MLM is a popular model in the strategy literature because it allows researchers to examine strategic choices with multiple outcomes. However, there see...... suitable for both interpretation and communication of results. The pratical steps are illustrated through an application of the MLM to the choice of foreign market entry mode.......This article provides guidelines and illustrates practical steps necessary for an analysis of results from the multinomial logit model (MLM). The MLM is a popular model in the strategy literature because it allows researchers to examine strategic choices with multiple outcomes. However, there seem...... to be systematic issues with regard to how researchers interpret their results when using the MLM. In this study, I present a set of guidelines critical to analyzing and interpreting results from the MLM. The procedure involves intuitive graphical representations of predicted probabilities and marginal effects...

  16. Competency in ECG Interpretation Among Medical Students

    Science.gov (United States)

    Kopeć, Grzegorz; Magoń, Wojciech; Hołda, Mateusz; Podolec, Piotr

    2015-01-01

    Background Electrocardiogram (ECG) is commonly used in diagnosis of heart diseases, including many life-threatening disorders. We aimed to assess skills in ECG interpretation among Polish medical students and to analyze the determinants of these skills. Material/Methods Undergraduates from all Polish medical schools were asked to complete a web-based survey containing 18 ECG strips. Questions concerned primary ECG parameters (rate, rhythm, and axis), emergencies, and common ECG abnormalities. Analysis was restricted to students in their clinical years (4th–6th), and students in their preclinical years (1st–3rd) were used as controls. Results We enrolled 536 medical students (females: n=299; 55.8%), aged 19 to 31 (23±1.6) years from all Polish medical schools. Most (72%) were in their clinical years. The overall rate of good response was better in students in years 4th–5th than those in years 1st–3rd (66% vs. 56%; pECG interpretation was higher in students who reported ECG self-learning (69% vs. 62%; pECG classes (66% vs. 66%; p=0.99). On multivariable analysis (pECG interpretation. Conclusions Polish medical students in their clinical years have a good level of competency in interpreting the primary ECG parameters, but their ability to recognize ECG signs of emergencies and common heart abnormalities is low. ECG interpretation skills are determined by self-education but not by attendance at regular ECG classes. Our results indicate qualitative and quantitative deficiencies in teaching ECG interpretation at medical schools. PMID:26541993

  17. Geothermal well log interpretation midterm report

    Energy Technology Data Exchange (ETDEWEB)

    Sanyal, S.K.; Wells, L.E.; Bickham, R.E.

    1979-02-01

    Reservoir types are defined according to fluid phase and temperature, lithology, geologic province, pore geometry, and salinity and fluid chemistry. Improvements are needed in lithology and porosity definition, fracture detection, and thermal evaluation for more accurate interpretation. Further efforts are directed toward improving diagnostic techniques for relating rock characteristics and log response, developing petrophysical models for geothermal systems, and developing thermal evaluation techniques. The Geothermal Well Log Interpretation study and report has concentrated only on hydrothermal geothermal reservoirs. Other geothermal reservoirs (hot dry rock, geopressured, etc.) are not considered.

  18. Aiding the Interpretation of Ancient Documents

    DEFF Research Database (Denmark)

    Roued-Cunliffe, Henriette

    How can Decision Support System (DSS) software aid the interpretation process involved in the reading of ancient documents? This paper discusses the development of a DSS prototype for the reading of ancient texts. In this context the term ‘ancient documents’ is used to describe mainly Greek...... tool it is important first to comprehend the interpretation process involved in reading ancient documents. This is not a linear process but rather a recursive process where the scholar moves between different levels of reading, such as ‘understanding the meaning of a character’ or ‘understanding...

  19. From Interpreter to Logic Engine by Defunctionalization

    DEFF Research Database (Denmark)

    Biernacki, Dariusz; Danvy, Olivier

    2003-01-01

    Starting from a continuation-based interpreter for a simple logic programming language, propositional Prolog with cut, we derive the corresponding logic engine in the form of an abstract machine. The derivation originates in previous work (our article at PPDP 2003) where it was applied to the lam......Starting from a continuation-based interpreter for a simple logic programming language, propositional Prolog with cut, we derive the corresponding logic engine in the form of an abstract machine. The derivation originates in previous work (our article at PPDP 2003) where it was applied...

  20. From Interpreter to Logic Engine by Defunctionalization

    DEFF Research Database (Denmark)

    Biernacki, Dariusz; Danvy, Olivier

    2004-01-01

    Starting from a continuation-based interpreter for a simple logic programming language, propositional Prolog with cut, we derive the corresponding logic engine in the form of an abstract machine. The derivation originates in previous work (our article at PPDP 2003) where it was applied to the lam......Starting from a continuation-based interpreter for a simple logic programming language, propositional Prolog with cut, we derive the corresponding logic engine in the form of an abstract machine. The derivation originates in previous work (our article at PPDP 2003) where it was applied...

  1. From Interpreter to logic Engine by Defunctionalization

    DEFF Research Database (Denmark)

    Biernacki, Dariusz; Danvy, Olivier

    2003-01-01

    Starting from a continuation-based interpreter for a simple logic programming language, propositional Prolog with cut, we derive the corresponding logic engine in the form of an abstract machine. The derivation originates in previous work (our article at PPDP 2003) where it was applied to the lam......Starting from a continuation-based interpreter for a simple logic programming language, propositional Prolog with cut, we derive the corresponding logic engine in the form of an abstract machine. The derivation originates in previous work (our article at PPDP 2003) where it was applied...

  2. Interpretation of Written Contracts in England

    Directory of Open Access Journals (Sweden)

    Neil Andrews

    2014-01-01

    Full Text Available This article examines the leading principles governing interpretation of written contracts under English law. This is a comprehensive and incisive analysis of the current law and of the relevant doctrines, including the equitable principles of rectification, as well as the powers of appeal courts or of the High Court when hearing an appeal from an arbitral award. The topic of interpretation of written contracts is fast-moving. It is of fundamental importance because this is the most significant commercial focus for dispute and because of the number of cross-border transactions to which English law is expressly applied by businesses.

  3. Three-dimensional interpretation of TEM soundings

    Science.gov (United States)

    Barsukov, P. O.; Fainberg, E. B.

    2013-07-01

    We describe the approach to the interpretation of electromagnetic (EM) sounding data which iteratively adjusts the three-dimensional (3D) model of the environment by local one-dimensional (1D) transformations and inversions and reconstructs the geometrical skeleton of the model. The final 3D inversion is carried out with the minimal number of the sought parameters. At each step of the interpretation, the model of the medium is corrected according to the geological information. The practical examples of the suggested method are presented.

  4. Are there realistically interpretable local theories?

    International Nuclear Information System (INIS)

    d'Espagnat, B.

    1989-01-01

    Although it rests on strongly established proofs, the statement that no realistically interpretable local theory is compatible with some experimentally testable predictions of quantum mechanics seems at first sight to be incompatible with a few general ideas and clear-cut statements occurring in recent theoretical work by Griffiths, Omnes, and Ballentine and Jarrett. It is shown here that in fact none of the developments due to these authors can be considered as a realistically interpretable local theory, so that there is no valid reason for suspecting that the existing proofs of the statement in question are all flawed

  5. A quark interpretation of the combinatorial hierarchy

    International Nuclear Information System (INIS)

    Enqvist, Kari.

    1979-01-01

    We propose a physical interpretation of the second level of the combinatorial hierarchy in terms of three quarks, three antiquarks and the vacuum. This interpretation allows us to introduce a new quantum number, which measures electromagnetic mass splitting of the quarks. We extend our argument by analogue to baryons, and find some SU(3) and some new mass formulas for baryons. The generalization of our approach to other hierarchy levels is discussed. We present also an empirical mass formula for baryons, which seems to be loosely connected with the combinatorial hierarchy. (author)

  6. List search hardware for interpretive software

    CERN Document Server

    Altaber, Jacques; Mears, B; Rausch, R

    1979-01-01

    Interpreted languages, e.g. BASIC, are simple to learn, easy to use, quick to modify and in general 'user-friendly'. However, a critically time consuming process during interpretation is that of list searching. A special microprogrammed device for fast list searching has therefore been developed at the SPS Division of CERN. It uses bit- sliced hardware. Fast algorithms perform search, insert and delete of a six-character name and its value in a list of up to 1000 pairs. The prototype shows retrieval times of the order of 10-30 microseconds. (11 refs).

  7. Noncommutative quantum mechanics and Bohm's ontological interpretation

    International Nuclear Information System (INIS)

    Barbosa, G.D.; Pinto-Neto, N.

    2004-01-01

    We carry out an investigation into the possibility of developing a Bohmian interpretation based on the continuous motion of point particles for noncommutative quantum mechanics. The conditions for such an interpretation to be consistent are determined, and the implications of its adoption for noncommutativity are discussed. A Bohmian analysis of the noncommutative harmonic oscillator is carried out in detail. By studying the particle motion in the oscillator orbits, we show that small-scale physics can have influence at large scales, something similar to the IR-UV mixing

  8. Control of nasal vasculature and airflow resistance in the dog.

    Science.gov (United States)

    Lung, M A; Phipps, R J; Wang, J C; Widdicombe, J G

    1984-01-01

    Nasal vascular and airflow resistances have been measured in dogs, simultaneously on both sides separately. Vascular resistance was measured either by constant flow perfusion of the terminal branch of the maxillary artery (which supplies, via the sphenopalatine artery, the nasal septum, most of the turbinates and the nasal sinuses) or by measuring blood flow through this artery, maintained by the dog's own blood pressure. Airflow resistance was assessed by inserting balloon-tipped endotracheal catheters into the back of each nasal cavity via the nasopharynx, and measuring transnasal pressure at constant airflow through each side of the nose simultaneously. Preliminary experiments indicated that there was 5-10% collateral anastomosis between the two sides. Close-arterial injection of drugs showed different patterns of response. Adrenaline, phenylephrine, chlorpheniramine and low doses of prostaglandin F2 alpha increased vascular resistance and lowered airway resistance. Salbutamol, methacholine and histamine lowered vascular resistance and increased airway resistance. Dobutamine decreased airway resistance with a small increase in vascular resistance. Prostaglandins E1, E2 and F2 alpha (high dose) decreased both vascular and airway resistances. Substance P, eledoisin-related peptide and vasoactive intestinal polypeptide lowered vascular resistance with little change in airway resistance. The results are interpreted in terms of possible drug actions on precapillary resistance vessels, sinusoids and venules, and arteriovenous anastomoses. It is concluded that nasal airway resistance cannot be correlated with vascular resistance or blood flow, since the latter has a complex and ill-defined relationship with nasal vascular blood volume. PMID:6204040

  9. Interpretive criteria of antimicrobial disk susceptibility tests with flomoxef.

    Science.gov (United States)

    Grimm, H

    1991-01-01

    320 recently isolated pathogens, 20 strains from each of 16 species, were investigated using Mueller-Hinton agar and DIN as well as NCCLS standards. The geometric mean of the agar dilution MICs of flomoxef were 0.44 mg/l for Staphylococcus aureus, 0.05 mg/l (Klebsiella oxytoca) to 12.6 mg/l (Enterobacter spp.) for enterobacteriaceae, 33.1 mg/l for Acinetobacter anitratus, 64 mg/l for Enterococcus faecalis, and more than 256 mg/l for Pseudomonas aeruginosa. For disk susceptibility testing of flomoxef a 30 micrograms disk loading and the following interpretation of inhibition zones using the DIN method were recommended: resistant-up to 22 mm (corresponding to MICs of 8 mg/l or more), moderately susceptible-23 to 29 mm (corresponding to MICs from 1 to 4 mg/l), and susceptible-30 mm or more (corresponding to MICs of 0.5 mg/l or less). The respective values for the NCCLS method using the American high MIC breakpoints are: resistant--up to 14 mm (corresponding to MICs of 32 mg/l or more), moderately susceptible--15 to 17 mm (corresponding to MICs of 16 mg/l), and susceptible--18 mm or more (corresponding to MICs of 8 mg/l or less).

  10. Self-analysis and the development of an interpretation.

    Science.gov (United States)

    Campbell, Donald

    2017-10-01

    In spite of the fact that Freud's self-analysis was at the centre of so many of his discoveries, self-analysis remains a complex, controversial and elusive exercise. While self-analysis is often seen as emerging at the end of an analysis and then used as a criteria in assessing the suitability for termination, I try to attend to the patient's resistance to self-analysis throughout an analysis. I take the view that the development of the patient's capacity for self-analysis within the analytic session contributes to the patient's growth and their creative and independent thinking during the analysis, which prepares him or her for a fuller life after the formal analysis ends. The model I will present is based on an over lapping of the patient's and the analyst's self-analysis, with recognition and use of the analyst's counter-transference. My focus is on the analyst's self-analysis that is in response to a particular crisis of not knowing, which results in feeling intellectually and emotionally stuck. This paper is not a case study, but a brief look at the process I went through to arrive at a particular interpretation with a particular patient during a particular session. I will concentrate on resistances in which both patient and analyst initially rely upon what is consciously known. Copyright © 2017 Institute of Psychoanalysis.

  11. Electromagnetic SAMPO monitoring soundings at Olkiluoto 2011 with updated interpretations

    International Nuclear Information System (INIS)

    Korhonen, K.

    2013-11-01

    The Geological Survey of Finland (GTK) has carried out electromagnetic depth soundings annually at fixed stations in Olkiluoto since 2004 as part of a monitoring programme. The goal of the programme is to detect and monitor changes in the electrical properties of the bedrock above and in the vicinity of the underground nuclear waste disposal facility. A new Sampo monitoring survey was carried out during September-October 2011. The survey resulted in 39 soundings at 17 measurement stations. The nominal coil separations of 200, 400, 500, 600 and 800 meters were used. Eight stations were selected for detailed annual layer-model interpretation. The layer models were based on prior geological and geophysical knowledge of the area. The thicknesses of the layer-model layers were kept fixed whereas their resistivities were solved for each subsequent year independent of each other. Many time series indicate clear trends in electrical resistivity. However, even though the data was carefully corrected and edited, the time series display a fairly large amount of variability increasing the uncertainty of the calculated trends. (orig.)

  12. Informal Interpreting in General Practice: Comparing the perspectives of General Practitioners, migrant patients and family interpreters.

    NARCIS (Netherlands)

    Zendedel, R.; Schouten, B.C.; van Weert, J.C.M.; van den Putte, B.

    Objective To explore differences in perspectives of general practitioners, Turkish-Dutch migrant patients and family interpreters on interpreters’ role, power dynamics and trust in interpreted GP consultations. Methods 54 semi-structured in-depth interviews were conducted with the three parties

  13. Court Interpreting in Denmark - the role of court interpreters in Danish courtrooms

    DEFF Research Database (Denmark)

    Jacobsen, Bente

    1999-01-01

    Court interpreters in Denmark are expected to follow the guidelines laid down in the document Instructions for Interpreters, which was published in 1994, and which deals with four principal areas: accuracy and completeness, impartiality, confidentiality and conflict of interest. This paper contends...

  14. 18 CFR 385.1901 - Interpretations and interpretative rules under the NGPA (Rule 1901).

    Science.gov (United States)

    2010-04-01

    ... to requests for interpretations to prospective, existing or completed facts, acts, or transactions..., knowledge, and belief there is no untrue statement of a material or relevant fact and there is no omission... misrepresented or omitted or if any material or relevant fact changes after an interpretation is issued or if the...

  15. Combined interpretation of multiple geophysical techniques: an archaeological case study

    Science.gov (United States)

    Riedl, S.; Reichmann, S.; Tronicke, J.; Lück, E.

    2009-04-01

    In order to locate and ascertain the dimensions of an ancient orangery, we explored an area of about 70 m x 60 m in the Rheinsberg Palace Garden (Germany) with multiple geophysical techniques. The Rheinsberg Park, situated about 100 km northwest of Berlin, Germany, was established by the Prussian emperors in the 18th century. Due to redesign of the architecture and the landscaping during the past 300 years, buildings were dismantled and detailed knowledge about some original buildings got lost. We surveyed an area close to a gazebo where, after historical sources, an orangery was planned around the year 1740. However, today it is not clear to what extent this plan has been realized and if remains of this building are still buried in the subsurface. Applied geophysical techniques include magnetic gradiometry, frequency domain electromagnetic (FDEM) and direct current (DC) resistivity mapping as well as ground penetrating radar (GPR). To get an overview of the site, we performed FDEM electrical conductivity mapping using an EM38 instrument and magnetic gradiometry with caesium magnetometers. Both data sets were collected with an in- and crossline data point spacing of ca. 10 cm and 50 cm, respectively. DC resistivity surveying was performed using a pole-pole electrode configuration with an electrode spacing of 1.5 m and a spacing of 1.0 m between individual readings. A 3-D GPR survey was conducted using 200 MHz antennae and in- and crossline spacing of ca. 10 cm and 40 cm, respectively. A standard processing sequence including 3-D migration was applied. A combined interpretation of all collected data sets illustrates that the magnetic gradient and the EM38 conductivity maps is are dominated by anomalies from metallic water pipes from belonging to the irrigation system of the park. The DC resistivity map outlines a rectangular area which might indicate the extension of a former building south of the gazebo. The 3-D GPR data set provides further insights about

  16. Resistance welding

    DEFF Research Database (Denmark)

    Bay, Niels; Zhang, Wenqi; Rasmussen, Mogens H.

    2003-01-01

    Resistance welding comprises not only the well known spot welding process but also more complex projection welding operations, where excessive plastic deformation of the weld point may occur. This enables the production of complex geometries and material combinations, which are often not possible...... to weld by traditional spot welding operations. Such joining processes are, however, not simple to develop due to the large number of parameters involved. Development has traditionally been carried out by large experimental investigations, but the development of a numerical programme system has changed...... this enabling prediction of the welding performance in details. The paper describes the programme in short and gives examples on industrial applications. Finally investigations of causes for failure in a complex industrial joint of two dissimilar metals are carried out combining numerical modelling...

  17. Antibiotic Resistance

    DEFF Research Database (Denmark)

    Hansen, Malene Plejdrup; Hoffmann, Tammy C; McCullough, Amanda R

    2015-01-01

    hygiene, and possibly vaccination and exercise, may be effective. Also, a large range of complementary and alternative medicines (e.g. zinc, vitamin C and probiotics) are proposed for preventing and treating ARIs, but evidence for efficacy is scarce. General practitioners' (GPs) attitudes towards...... wrong. Shared decision making might be a solution, as it enables clinician and patient to participate jointly in making a health decision, having discussed the options together with the evidence for their harms as well as benefits. Furthermore, GPs' diagnostic uncertainty - often leading...... will greatly improve the use of antibiotics for ARIs. However, used in concert, combinations are likely to enable clinicians and health care systems to implement the strategies that will reduce antimicrobial resistance in the future....

  18. Resisting dehumanization

    DEFF Research Database (Denmark)

    Lassen, Inger Marie

    2018-01-01

    Recent years have seen an increase in the influx of asylum-seekers in Scandinavia, and in Denmark this has led to ever-tighter immigration control. This article discusses emerging practices of refugee solidarity and resistance to hegemonic migration policy in Danish civil society in the wake...... of what has been referred to as the European refugee crisis. It further reflects upon what it means to be a Danish citizen facing the dilemma of law-abiding conduct versus human decency, in line with what Foucault (1983) referred to as ‘ethical self-formation’. This is illustrated through a case study...... of an incident from September 2015, when a member of a Danish City Council offered private shelter to immigrants who were on their way to Norway. The incident led to legal proceedings in August 2016 for what the defendant referred to as ‘the offense of helping fellow human beings in need’. The study is informed...

  19. A clustering approach applied to time-lapse ERT interpretation - Case study of Lascaux cave

    Science.gov (United States)

    Xu, Shan; Sirieix, Colette; Riss, Joëlle; Malaurent, Philippe

    2017-09-01

    The Lascaux cave, located in southwest France, is one of the most important prehistoric cave in the world that shows Paleolithic paintings. This study aims to characterize the structure of the weathered epikarst setting located above the cave using Time-Lapse Electrical Resistivity Tomography (ERT) combined with local hydrogeological and climatic environmental data. Twenty ERT profiles were carried out for two years and helped us to record the seasonal and spatial variations of the electrical resistivity of the hydraulic upstream area of the Lascaux cave. The 20 interpreted resistivity models were merged into a single synthetic model using a multidimensional statistical method (Hierarchical Agglomerative Clustering). The individual blocks from the synthetic model associated with a similar resistivity variability were gathered into 7 clusters. We combined the resistivity temporal variations with climatic and hydrogeological data to propose a geo-electrical model that relates to a conceptual geological model. We provide a geological interpretation for each cluster regarding epikarst features. The superficial clusters (no 1 & 2) are linked to effective rainfall and trees, probably a fractured limestone. Another two clusters (no 6 & 7) are linked to detrital formations (sand and clay respectively). The cluster 3 may correspond to a marly limestone that forms a non-permeable horizon. Finally, the electrical behavior of the last two clusters (no 4 & 5) is correlated with the variation of flow rate; they may be a privileged feed zone of the flow in the cave.

  20. Interpretability degrees of finitely axiomatized sequential theories

    NARCIS (Netherlands)

    Visser, Albert

    In this paper we show that the degrees of interpretability of finitely axiomatized extensions-in-the-same-language of a finitely axiomatized sequential theory-like Elementary Arithmetic EA, IΣ1, or the Gödel-Bernays theory of sets and classes GB-have suprema. This partially answers a question posed

  1. Interpretability Degrees of Finitely Axiomatized Sequential Theories

    NARCIS (Netherlands)

    Visser, Albert

    2012-01-01

    In this paper we show that the degrees of interpretability of finitely axiomatized extensions-in-the-same-language of a finitely axiomatized sequential theory —like Elementary Arithmetic EA, IΣ1, or the Gödel-Bernays theory of sets and classes GB— have suprema. This partially answers a question

  2. Modeling and interpretation of line observations*

    Directory of Open Access Journals (Sweden)

    Kamp Inga

    2015-01-01

    Full Text Available Models for the interpretation of line observations from protoplanetary disks are summarized. The spectrum ranges from 1D LTE slab models to 2D thermo-chemical radiative transfer models and their use depends largely on the type/nature of observational data that is analyzed. I discuss the various types of observational data and their interpretation in the context of disk physical and chemical properties. The most simple spatially and spectral unresolved data are line fluxes, which can be interpreted using so-called Boltzmann diagrams. The interpretation is often tricky due to optical depth and non-LTE effects and requires care. Line profiles contain kinematic information and thus indirectly the spatial origin of the emission. Using series of line profiles, we can for example deduce radial temperature gradients in disks (CO pure rotational ladder. Spectro-astrometry of e.g. CO ro-vibrational line profiles probes the disk structure in the 1–30 AU region, where planet formation through core accretion should be most efficient. Spatially and spectrally resolved line images from (submm interferometers are the richest datasets we have to date and they enable us to unravel exciting details of the radial and vertical disk structure such as winds and asymmetries.

  3. Collecting and Interpreting Qualitative Materials. Third Edition

    Science.gov (United States)

    Denzin, Norman K., Ed.; Lincoln, Yvonna, Ed.

    2007-01-01

    This book is the third volume of the paperback versions of "The SAGE Handbook of Qualitative Research, Third Edition." This portion of the handbook considers the tasks of collecting, analyzing, and interpreting empirical materials, and comprises the Handbook's Parts IV ("Methods of Collecting and Analyzing Empirical Materials") and V ("The Art and…

  4. Interpretation of Confidence Interval Facing the Conflict

    Science.gov (United States)

    Andrade, Luisa; Fernández, Felipe

    2016-01-01

    As literature has reported, it is usual that university students in statistics courses, and even statistics teachers, interpret the confidence level associated with a confidence interval as the probability that the parameter value will be between the lower and upper interval limits. To confront this misconception, class activities have been…

  5. Teacher experiences of generating and interpreting drawings

    African Journals Online (AJOL)

    I report on a phenomenological investigation into teacher experiences of generating and interpreting drawings during their participation in the Resilient Educators (REds) intervention. All 18 teacher participants came from rural communities challenged by HIV&AIDS. I reflect critically on the ambivalence in teacher ...

  6. CONSTITUTIONAL INTERPRETATION OF ROMANIA: POST MODERNITY

    Directory of Open Access Journals (Sweden)

    P. RATHNASWAMY

    2017-06-01

    Full Text Available Austria had in 1920 Constitutional Court followed by Italy in 1946, Germany in 1949, Romania in 1989, South Africa in 1991, and Ethiopia in 1995. Each Constitution has its provisions on the constitutional interpretation. Romania has its own provisions and it is considered here its legality and the best possible measures and recommendations for future. Judicial power is vested in judiciary to interpret constitution, laws, and actions of other organs of government. Judicial review is the function resulted upon judicial power. Political body joins through the appointment of its members in the judicial review and it limits the independence of judiciary. It also reduces the values of separation of powers. Challenges and opportunities of growth and development do influence the spirit of separation of powers and judicial independence. The principle of inherent judicial power in judiciary inducts upon the constitutional interpretation. Thus, the principles of constitutional interpretation are varying in Romania and other similar constitutional courts of Germany, Ethiopia, and Italy but not in South Africa.

  7. Galileo and the Interpretation of the Bible.

    Science.gov (United States)

    Carroll, William E.

    1999-01-01

    Argues that, contrary to the common view, Galileo and the theologians of the Inquisition share the same fundamental principles of biblical interpretation. Contends that Galileo and these theologians thought that the Bible contained truths about nature, but Galileo denied what the theologians accepted as scientifically true. Contains 93 references.…

  8. Towards a Quantum Mechanical Interpretation of Homeopathy

    NARCIS (Netherlands)

    Wilkinson, Michael H.F.

    1999-01-01

    A quantum interpretation of the homeopathic method is presented. It is shown that provided neither the medication itself, nor the patient is observed, a net effect is expected, even at homeopathic dilutions. The temporal dilution in homeopathic exercise is explained in terms of Heisenberg's theory

  9. Convolutional Neural Networks - Generalizability and Interpretations

    DEFF Research Database (Denmark)

    Malmgren-Hansen, David

    from data despite it being limited in amount or context representation. Within Machine Learning this thesis focuses on Convolutional Neural Networks for Computer Vision. The research aims to answer how to explore a model's generalizability to the whole population of data samples and how to interpret...

  10. Interpretable neural networks with BP-SOM

    NARCIS (Netherlands)

    Weijters, A.J.M.M.; Bosch, van den A.P.J.; Pobil, del A.P.; Mira, J.; Ali, M.

    1998-01-01

    Artificial Neural Networks (ANNS) are used successfully in industry and commerce. This is not surprising since neural networks are especially competitive for complex tasks for which insufficient domain-specific knowledge is available. However, interpretation of models induced by ANNS is often

  11. 48 CFR 9905.502-61 - Interpretation.

    Science.gov (United States)

    2010-10-01

    ... to it as a direct cost any cost, if other costs incurred for the same purpose, in like circumstances... to all work of the educational institution. (d) This interpretation does not preclude the allocation... by the educational institution, however, must be followed consistently and the method used to...

  12. Interpretation of Aeromagnetic Anomalies over Abeokuta, Southwest ...

    African Journals Online (AJOL)

    ADOWIE PERE

    shallow depth and deeper depths to be 0.467 km and. 2.797 km ... the most widespread rock information within the study area. ... 20 km. For onward processing and interpretation, the data was ... indicate the deep and shallow seated magnetic.

  13. 20 CFR 602.11 - Secretary's interpretation.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Secretary's interpretation. 602.11 Section 602.11 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR QUALITY CONTROL... methods of administration as will reasonably ensure the prompt and full payment of unemployment benefits...

  14. From Interpreter to Logic Engine by Defunctionalization

    DEFF Research Database (Denmark)

    Biernacki, Dariusz; Danvy, Olivier

    2004-01-01

    Starting from a continuation-based interpreter for a simple logic programming language, propositional Prolog with cut, we derive the corresponding logic engine in the form of an abstract machine. The derivation originates in previous work (our article at PPDP 2003) where it was applied...

  15. From Interpreter to Logic Engine by Defunctionalization

    DEFF Research Database (Denmark)

    Biernacki, Dariusz; Danvy, Olivier

    2003-01-01

    Starting from a continuation-based interpreter for a simple logic programming language, propositional Prolog with cut, we derive the corresponding logic engine in the form of an abstract machine. The derivation originates in previous work (our article at PPDP 2003) where it was applied...

  16. 7 CFR 201.56 - Interpretation.

    Science.gov (United States)

    2010-01-01

    ... REGULATIONS Germination Tests in the Administration of the Act § 201.56 Interpretation. (a) A seed shall be... and the final count. During the progress of the germination test, seeds which are obviously dead and... evaluation of germination tests made on approved artificial media. This is intended to provide a method of...

  17. Interpretive policy analysis in the Netherlands

    NARCIS (Netherlands)

    van Bommel, Severine; van Hulst, M.J.; Yanow, Dvora; van Nispen, Frans; Scholten, Peter

    2014-01-01

    This chapter outlines the character of interpretive policy analysis (IPA) and then looks at the history and present state of its practice in the Netherlands. In an approach commonly found in science studies, that history is traced through key actors and their publications, institutional locations,

  18. Causal Indicators Can Help to Interpret Factors

    Science.gov (United States)

    Bentler, Peter M.

    2016-01-01

    The latent factor in a causal indicator model is no more than the latent factor of the factor part of the model. However, if the causal indicator variables are well-understood and help to improve the prediction of individuals' factor scores, they can help to interpret the meaning of the latent factor. Aguirre-Urreta, Rönkkö, and Marakas (2016)…

  19. Feedforward: helping students interpret written feedback

    OpenAIRE

    Hurford, Donna; Read, Andrew

    2008-01-01

    "Assessment for Learning is the process of seeking and interpreting evidence for use by learners... "(Assessment Reform Group, 2002, p.2): for the Higher Education tutor, written feedback forms an integral part of this. This short article reports on teaching methods to engage students in feedback and assessment of their written work.

  20. A Theoretical Foundation for Tilden's Interpretive Principles.

    Science.gov (United States)

    Hammitt, William E.

    1981-01-01

    Draws from perceptual and cognitive psychology to present a theoretical basis for the principles of interpretation developed by Freeman Tilden. Emphasized is cognitive map theory which holds that information units people receive, code and store are structured into cognitive models intended to represent the environment. (Author/WB)

  1. Interpreter's Guide to Blackbird Marsh Nature Trail.

    Science.gov (United States)

    Environmental Studies Center, Pensacola, FL.

    This booklet was prepared to help the user interpret the natural history of Blackbird Marsh Nature Trail in Escambia County, Florida, and serves as a guide to the animal and plant life. The publication is part of a series of illustrated guides designed for use by teachers and students of all levels in conjunction with field trips to the 1200-acre…

  2. Synchrony in diachronic analysis: the interpretation of

    NARCIS (Netherlands)

    Vis, J.; Kitis, E.; Lavidas, N.; Topintzi, N.; Tsangalidis, T.

    2011-01-01

    In historical linguistics, it is very common to interpret the data mainly by means of a diachronic approach. In this article, I will claim that, a combination of various linguistic methods, including a synchronic analysis and cross-linguistic parallels, leads to better motivated conclusions. I will

  3. Developing Interpretive Power in Science Teaching

    Science.gov (United States)

    Rosebery, Ann S.; Warren, Beth; Tucker-Raymond, Eli

    2016-01-01

    Early career teachers rarely receive sustained support for addressing issues of diversity and equity in their science teaching. This paper reports on design research to create a 30 hour professional development seminar focused on cultivating the interpretive power of early career teachers who teach science to students from historically…

  4. Video interpretability rating scale under network impairments

    Science.gov (United States)

    Kreitmair, Thomas; Coman, Cristian

    2014-01-01

    This paper presents the results of a study of the impact of network transmission channel parameters on the quality of streaming video data. A common practice for estimating the interpretability of video information is to use the Motion Imagery Quality Equation (MIQE). MIQE combines a few technical features of video images (such as: ground sampling distance, relative edge response, modulation transfer function, gain and signal-to-noise ratio) to estimate the interpretability level. One observation of this study is that the MIQE does not fully account for video-specific parameters such as spatial and temporal encoding, which are relevant to appreciating degradations caused by the streaming process. In streaming applications the main artifacts impacting the interpretability level are related to distortions in the image caused by lossy decompression of video data (due to loss of information and in some cases lossy re-encoding by the streaming server). One parameter in MIQE that is influenced by network transmission errors is the Relative Edge Response (RER). The automated calculation of RER includes the selection of the best edge in the frame, which in case of network errors may be incorrectly associated with a blocked region (e.g. low resolution areas caused by loss of information). A solution is discussed in this document to address this inconsistency by removing corrupted regions from the image analysis process. Furthermore, a recommendation is made on how to account for network impairments in the MIQE, such that a more realistic interpretability level is estimated in case of streaming applications.

  5. The metaphysics of quantum mechanics: Modal interpretations

    Science.gov (United States)

    Gluck, Stuart Murray

    2004-11-01

    This dissertation begins with the argument that a preferred way of doing metaphysics is through philosophy of physics. An understanding of quantum physics is vital to answering questions such as: What counts as an individual object in physical ontology? Is the universe fundamentally indeterministic? Are indiscernibles identical? This study explores how the various modal interpretations of quantum mechanics answer these sorts of questions; modal accounts are one of the two classes of interpretations along with so-called collapse accounts. This study suggests a new alternative within the class of modal views that yields a more plausible ontology, one in which the Principle of the Identity of Indisceribles is necessarily true. Next, it shows that modal interpretations can consistently deny that the universe must be fundamentally indeterministic so long as they accept certain other metaphysical commitments: either a perfect initial distribution of states in the universe or some form of primitive dispositional properties. Finally, the study sketches out a future research project for modal interpretations based on developing quantified quantum logic.

  6. 48 CFR 9904.402-61 - Interpretation.

    Science.gov (United States)

    2010-10-01

    ...-61 Section 9904.402-61 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.402-61 Interpretation. (a) 9904.402, Cost Accounting...

  7. 48 CFR 9904.406-61 - Interpretation.

    Science.gov (United States)

    2010-10-01

    ...-61 Section 9904.406-61 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.406-61 Interpretation. (a) Questions have arisen as to...

  8. 48 CFR 9904.403-61 - Interpretation.

    Science.gov (United States)

    2010-10-01

    ...-61 Section 9904.403-61 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.403-61 Interpretation. (a) Questions have arisen as to...

  9. 48 CFR 9904.401-61 - Interpretation.

    Science.gov (United States)

    2010-10-01

    ...-61 Section 9904.401-61 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.401-61 Interpretation. (a) 9904.401, Cost Accounting...

  10. Forest Interpreter's Primer on Fire Management.

    Science.gov (United States)

    Zelker, Thomas M.

    Specifically prepared for the use of Forest Service field-based interpreters of the management, protection, and use of forest and range resources and the associated human, cultural, and natural history found on these lands, this book is the second in a series of six primers on the multiple use of forest and range resources. Following an…

  11. Life Interpretation and Religion among Icelandic Teenagers

    Science.gov (United States)

    Gunnarsson, Gunnar J.

    2009-01-01

    Does religion play any specific part in Icelandic teenagers' life interpretation? This paper examines Icelandic teenagers' talk about religion and presents some of the findings in interviews with teenagers in a qualitative research project. The focus is especially on how three individuals express themselves about the influence of religion on their…

  12. Charts for interpreting wildland fire behavior characteristics

    Science.gov (United States)

    Patricia L. Andrews; Richard C. Rothermel

    1982-01-01

    The fire characteristics chart is proposed as a graphical method ofpresenting two primary characteristics of fire behavior – spread rate and intensity. Its primary use is communicating and interpreting either site-specific predictions of fire behavior or National Fire-Danger Rating System (NFDRS) indexes and components. Rate of spread, heat per unit area, flame length...

  13. [Interpretation of proverbs and Alzheimer's disease].

    Science.gov (United States)

    Báez, S; Mendoza, L; Reyes, P; Matallana, D; Montañés, P

    To evaluate the performance of patients with Alzheimer's disease (AD) in the mild-moderate stage in a verbal material abstraction task that involves interpreting the implicit meaning of proverbs and sayings. A qualitative-quantitative analysis was carried out of the performance of 30 patients with AD and 30 controls, paired by age, gender and level of education. Patients had significantly greater difficulties than the controls when it came to interpreting proverbs. A high correlation was found between subjects' years of schooling and the overall score on the proverb interpretation test. Results suggest that the processes that may be predominantly affected in patients with AD are the investigation of the conditions of the problem, together with selecting an alternative and formulating a cognitive plan to resolve the task. The results help to further our knowledge of the characteristics of performance of patients with AD in a test involving the interpretation of the implicit meaning of proverbs and also provide information about the processes that may be predominantly affected. Further research is needed, however, on this subject area in order to obtain more conclusive explanations.

  14. Coherent discourse solves the pronoun interpretation problem

    NARCIS (Netherlands)

    Spenader, J.K.; Smits, Erik; Hendriks, P.

    Many comprehension studies have shown that children as late as age 6;6 misinterpret object pronouns as co-referring with the referential subject about half the time. A recent review of earlier experiments testing children's interpretation of object pronouns in sentences with quantified subjects

  15. Biased Facial Expression Interpretation in Shy Children

    Science.gov (United States)

    Kokin, Jessica; Younger, Alastair; Gosselin, Pierre; Vaillancourt, Tracy

    2016-01-01

    The relationship between shyness and the interpretations of the facial expressions of others was examined in a sample of 123 children aged 12 to 14?years. Participants viewed faces displaying happiness, fear, anger, disgust, sadness, surprise, as well as a neutral expression, presented on a computer screen. The children identified each expression…

  16. Interpreting XML documents via an RDF schema

    NARCIS (Netherlands)

    Klein, Michel; Handschuh, Siegfried; Staab, Steffen

    2003-01-01

    One of the major problems in the realization of the vision of the ``Semantic Web''; is the transformation of existing web data into sources that can be processed and used by machines. This paper presents a procedure that can be used to turn XML documents into knowledge structures, by interpreting

  17. Combined interpretation of SkyTEM and high-resolution seismic data

    DEFF Research Database (Denmark)

    Høyer, Anne-Sophie; Lykke-Andersen, Holger; Jørgensen, Flemming Voldum

    2011-01-01

    made based on AEM (SkyTEM) and high-resolution seismic data from an area covering 10 km2 in the western part of Denmark. As support for the interpretations, an exploration well was drilled to provide lithological and logging information in the form of resistivity and vertical seismic profiling. Based...... on the resistivity log, synthetic SkyTEM responses were calculated with a varying number of gate-times in order to illustrate the effect of the noise-level. At the exploration well geophysical data were compared to the lithological log; in general there is good agreement. The same tendency was recognised when Sky...

  18. Electrocardiogram interpretation skills among ambulance nurses.

    Science.gov (United States)

    Werner, Kristoffer; Kander, Kristofer; Axelsson, Christer

    2016-06-01

    To describe ambulance nurses' practical electrocardiogram (ECG) interpretation skills and to measure the correlation between these skills and factors that may impact on the level of knowledge. This study was conducted using a prospective quantitative survey with questionnaires and a knowledge test. A convenience sample collection was conducted among ambulance nurses in three different districts in western Sweden. The knowledge test consisted of nine different ECGs. The score of the ECG test were correlated against the questions in the questionnaire regarding both general ECG interpretation skill and ability to identify acute myocardial infarction using Mann-Whitney U test, Kruskal-Wallis test and Spearman's rank correlation. On average, the respondents had 54% correct answers on the test and identified 46% of the ECGs indicating acute myocardial infarction. The median total score was 9 of 16 (interquartile range 7-11) and 1 of 3 (IQR 1-2) in infarction points. No correlation between ECG interpretation skill and factors such as education and professional experience was found, except that coronary care unit experience was associated with better results on the ECG test. Ambulance nurses have deficiencies in their ECG interpretation skills. This also applies to conditions where the ambulance crew has great potential to improve the outcome of the patient's health, such as myocardial infarction and cardiac arrest. Neither education, extensive experience in ambulance service nor in nursing contributed to an improved result. The only factor of importance for higher ECG interpretation knowledge was prior experience of working in a coronary care unit. © The European Society of Cardiology 2014.

  19. Interpreting parameters in the logistic regression model with random effects

    DEFF Research Database (Denmark)

    Larsen, Klaus; Petersen, Jørgen Holm; Budtz-Jørgensen, Esben

    2000-01-01

    interpretation, interval odds ratio, logistic regression, median odds ratio, normally distributed random effects......interpretation, interval odds ratio, logistic regression, median odds ratio, normally distributed random effects...

  20. Informal interpreting in general practice: Are interpreters' roles related to perceived control, trust, and satisfaction?

    Science.gov (United States)

    Zendedel, Rena; Schouten, Barbara C; van Weert, Julia C M; van den Putte, Bas

    2018-06-01

    The aim of this observational study was twofold. First, we examined how often and which roles informal interpreters performed during consultations between Turkish-Dutch migrant patients and general practitioners (GPs). Second, relations between these roles and patients' and GPs' perceived control, trust in informal interpreters and satisfaction with the consultation were assessed. A coding instrument was developed to quantitatively code informal interpreters' roles from transcripts of 84 audio-recorded interpreter-mediated consultations in general practice. Patients' and GPs' perceived control, trust and satisfaction were assessed in a post consultation questionnaire. Informal interpreters most often performed the conduit role (almost 25% of all coded utterances), and also frequently acted as replacers and excluders of patients and GPs by asking and answering questions on their own behalf, and by ignoring and omitting patients' and GPs' utterances. The role of information source was negatively related to patients' trust and the role of GP excluder was negatively related to patients' perceived control. Patients and GPs are possibly insufficiently aware of the performed roles of informal interpreters, as these were barely related to patients' and GPs' perceived trust, control and satisfaction. Patients and GPs should be educated about the possible negative consequences of informal interpreting. Copyright © 2018 Elsevier B.V. All rights reserved.

  1. On Thermodynamic Interpretation of Transfer Entropy

    Directory of Open Access Journals (Sweden)

    Don C. Price

    2013-02-01

    Full Text Available We propose a thermodynamic interpretation of transfer entropy near equilibrium, using a specialised Boltzmann’s principle. The approach relates conditional probabilities to the probabilities of the corresponding state transitions. This in turn characterises transfer entropy as a difference of two entropy rates: the rate for a resultant transition and another rate for a possibly irreversible transition within the system affected by an additional source. We then show that this difference, the local transfer entropy, is proportional to the external entropy production, possibly due to irreversibility. Near equilibrium, transfer entropy is also interpreted as the difference in equilibrium stabilities with respect to two scenarios: a default case and the case with an additional source. Finally, we demonstrated that such a thermodynamic treatment is not applicable to information flow, a measure of causal effect.

  2. Interpreting peptide mass spectra by VEMS

    DEFF Research Database (Denmark)

    Mathiesen, Rune; Lundsgaard, M.; Welinder, Karen G.

    2003-01-01

    the calculated and the experimental mass spectrum of the called peptide. The program package includes four accessory programs. VEMStrans creates protein databases in FASTA format from EST or cDNA sequence files. VEMSdata creates a virtual peptide database from FASTA files. VEMSdist displays the distribution......Most existing Mass Spectra (MS) analysis programs are automatic and provide limited opportunity for editing during the interpretation. Furthermore, they rely entirely on publicly available databases for interpretation. VEMS (Virtual Expert Mass Spectrometrist) is a program for interactive analysis...... of peptide MS/MS spectra imported in text file format. Peaks are annotated, the monoisotopic peaks retained, and the b-and y-ion series identified in an interactive manner. The called peptide sequence is searched against a local protein database for sequence identity and peptide mass. The report compares...

  3. Interpreting Quantum Logic as a Pragmatic Structure

    Science.gov (United States)

    Garola, Claudio

    2017-12-01

    Many scholars maintain that the language of quantum mechanics introduces a quantum notion of truth which is formalized by (standard, sharp) quantum logic and is incompatible with the classical (Tarskian) notion of truth. We show that quantum logic can be identified (up to an equivalence relation) with a fragment of a pragmatic language LGP of assertive formulas, that are justified or unjustified rather than trueor false. Quantum logic can then be interpreted as an algebraic structure that formalizes properties of the notion of empirical justification according to quantum mechanics rather than properties of a quantum notion of truth. This conclusion agrees with a general integrationist perspective that interprets nonstandard logics as theories of metalinguistic notions different from truth, thus avoiding incompatibility with classical notions and preserving the globality of logic.

  4. Probabilistic interpretation of data a physicist's approach

    CERN Document Server

    Miller, Guthrie

    2013-01-01

    This book is a physicists approach to interpretation of data using Markov Chain Monte Carlo (MCMC). The concepts are derived from first principles using a style of mathematics that quickly elucidates the basic ideas, sometimes with the aid of examples. Probabilistic data interpretation is a straightforward problem involving conditional probability. A prior probability distribution is essential, and examples are given. In this small book (200 pages) the reader is led from the most basic concepts of mathematical probability all the way to parallel processing algorithms for Markov Chain Monte Carlo. Fortran source code (for eigenvalue analysis of finite discrete Markov Chains, for MCMC, and for nonlinear least squares) is included with the supplementary material for this book (available online).

  5. Antibiotic Resistance in Pediatric Urinary Tract Infections.

    Science.gov (United States)

    Stultz, Jeremy S; Doern, Christopher D; Godbout, Emily

    2016-12-01

    Urinary tract infections (UTIs) are a common problem in pediatric patients. Resistance to common antibiotic agents appears to be increasing over time, although resistance rates may vary based on geographic region or country. Prior antibiotic exposure is a pertinent risk factor for acquiring resistant organisms during a first UTI and recurrent UTI. Judicious prescribing of antibiotics for common pediatric conditions is needed to prevent additional resistance from occurring. Complex pediatric patients with histories of hospitalizations, prior antibiotic exposure, and recurrent UTIs are also at high risk for acquiring UTIs due to extended spectrum beta-lactamase-producing organisms. Data regarding the impact of in vitro antibiotic susceptibility testing interpretation on UTI treatment outcomes is lacking.

  6. The interpretation of the iota meson

    International Nuclear Information System (INIS)

    Frank, M.

    1985-01-01

    The authors analyze the iota (1440) meson in a non-relativistic quark model. The authors review the experimental data, then attempt to incorporate it in the mass spectrum and radiative decays of the low-lying pseudoscalar and vector mesons. Correlating these results with production decay rates from J/psi and the radiative decays of iota, the authors conclude that the iota has to be interpreted as having a strong gluonium component

  7. Interpreting the CMMI a process improvement approach

    CERN Document Server

    Kulpa, Margaret K

    2008-01-01

    Written by experienced process improvement professionals who have developed and implemented computer based systems in organizations around the world, Interpreting the CMMI®: A Process Improvement Approach, Second Edition provides you with specific techniques for performing process improvement. Employing everyday language and supported by real world examples, the authors describe the fundamental concepts of the CMMI model, covering goals, practices, architecture, and definitions, and provide a structured approach for implementing the concepts of the CMMI into any organization. They discuss gett

  8. Interpretation of commonly used statistical regression models.

    Science.gov (United States)

    Kasza, Jessica; Wolfe, Rory

    2014-01-01

    A review of some regression models commonly used in respiratory health applications is provided in this article. Simple linear regression, multiple linear regression, logistic regression and ordinal logistic regression are considered. The focus of this article is on the interpretation of the regression coefficients of each model, which are illustrated through the application of these models to a respiratory health research study. © 2013 The Authors. Respirology © 2013 Asian Pacific Society of Respirology.

  9. New Interpretation of the Wigner Function

    Science.gov (United States)

    Daboul, Jamil

    1996-01-01

    I define a two-sided or forward-backward propagator for the pseudo-diffusion equation of the 'squeezed' Q function. This propagator leads to squeezing in one of the phase-space variables and anti-squeezing in the other. By noting that the Q function is related to the Wigner function by a special case of the above propagator, I am led to a new interpretation of the Wigner function.

  10. Quasi-equilibrium interpretation of aging dynamics

    International Nuclear Information System (INIS)

    Franz, S.; Virasoro, M.A.

    2000-04-01

    We develop an interpretation of the off-equilibrium dynamical solution of mean-field glassy models in terms of quasi-equilibrium concepts. We show that the relaxation of the 'thermoremanent magnetization' follows a generalized version of the Onsager regression postulate of induced fluctuations. We then find the rationale for the equality between the fluctuation-dissipation ratio and the rate of growth of the configurational entropy close to the asymptotic state, found empirically in mean-field solutions. (author)

  11. Interpretation of radiograms using digital computers

    International Nuclear Information System (INIS)

    Kuzin, M.I.; Den'shchikov, K.K.; Sal'man, M.M.; Pechennikov, L.M.

    1986-01-01

    The potentialities of the use of a combined method of interactive and automated processing of radiograms with the help of digital computers (DC) are discussed. The data obtained have shown that DC-assissted interpretation of radiograms makes it possible to detect small formations in the chest undectable in a routine X-ray examination. However there can occur undesirable false detection of pathology resulting from algorithm sensitivity

  12. Internal disruptions in Tokamak: a turbulent interpretation

    International Nuclear Information System (INIS)

    Dubois, M.A.; Pecquet, A.L.; Reverdin, C.

    1982-07-01

    High speed X-ray data of sawteeth in TFR are interpreted using a kinematic model. It is shown that the internal disruption begins for a small size of the q = 1 island, and that the sharp details observed on different chords are not reproduced by a total reconnection model. Conversely they are well simulated by a model where the temperature flattening is due to the propagation of a turbulent region starting from the q = 1 surface

  13. PROBABLE FORECASTING IN THE COURSE OF INTERPRETING

    Directory of Open Access Journals (Sweden)

    Ye. B. Kagan

    2017-01-01

    Full Text Available Introduction. Translation practice has a heuristic nature and involves cognitive structures of consciousness of any interpreter. When preparing translators, special attention is paid to the development of their skill of probable forecasting.The aim of the present publication is to understand the process of anticipation from the position of the cognitive model of translation, development of exercises aimed at the development of prognostic abilities of students and interpreters when working with newspaper articles, containing metaphorical headlines.Methodology and research methods. The study is based on the competence approach to the training of students-translators, the complex of interrelated scientific methods, the main of which is the psycholinguistic experiment. With the use of quantitative data the features of the perception of newspaper texts on their metaphorical titles are characterized.Results and scientific novelty. On the basis of the conducted experiment to predict the content of newspaper articles with metaphorical headlines it is concluded that the main condition of predictability is the expectation. Probable forecasting as a professional competence of a future translator is formed in the process of training activities by integrating efforts of various departments of any language university. Specific exercises for the development of anticipation of students while studying the course of translation and interpretation are offered.Practical significance. The results of the study can be used by foreign language teachers of both language and non-language universities in teaching students of different specialties to translate foreign texts. 

  14. Problems in black-hole entropy interpretation

    International Nuclear Information System (INIS)

    Liberati, S.

    1997-01-01

    In this work some proposals for black-hole entropy interpretation are exposed and investigated. In particular, the author will firstly consider the so-called 'entanglement entropy' interpretation, in the framework of the brick wall model and the divergence problem arising in the one-loop calculations of various thermodynamical quantities, like entropy, internal energy and heat capacity. It is shown that the assumption of equality of entanglement entropy and Bekenstein-Hawking one appears to give inconsistent results. These will be a starting point for a different interpretation of black.hole entropy based on peculiar topological structures of manifolds with 'intrinsic' thermodynamical features. It is possible to show an exact relation between black-hole gravitational entropy and topology of these Euclidean space-times. the expression for the Euler characteristic, through the Gauss-Bonnet integral, and the one for entropy for gravitational instantons are proposed in a form which makes the relation between these self-evident. Using this relation he propose a generalization of the Bekenstein-Hawking entropy in which the former and Euler characteristic are related in the equation S = χA / 8. Finally, he try to expose some conclusions and hypotheses about possible further development of this research

  15. Sites of Sign-Production and Interpretation

    Directory of Open Access Journals (Sweden)

    Maria-Ana Tupan

    2016-03-01

    Full Text Available T.S. Eliot’s query in The Waste Land, “Who is the third who walks always beside you?” may be said to sum up the hermeneutic situation of any language act, whether of sign production or interpretation. Whereas traditional topoi of expressionist aesthetics, such as the artist’s subjectivity, empirical psychology, truthfulness, intentionality, etc. have become irrelevant in the heteroglottic discourse of the most famous dirge on the decaying West, Eliot’s awareness of the matrical role of cultural semiosis allows us to place him among the founding fathers of semiotic aesthetics. The anagnorisis episode in The Waste Land is one of appropriate reading of the body of Christ through knowledge of the crucifixion scene and associated symbolism.Rooted in the insights of Charles Peirce Sanders and Charles Morris, and enlarged by post-war contributors, such as Roland Barthes, Umberto Eco, Michael B. Hardt, Richard Rudner, Foucault, Vattimo, Baudrillard and Deleuze, the semiotic, cultural materialist, or genetic approach  to art makes interpretation dependent on a mediating third (Peirce: the Interpretant, which is variously related to context, regime of signification, episteme, schemata, generic convention, structure of feeling, triangulation of desire ...

  16. An objective interpretation of Lagrangian quantum mechanics

    International Nuclear Information System (INIS)

    Roberts, K.V.

    1978-01-01

    Unlike classical mechanics, the Copenhagen interpretation of quantum mechanics does not provide an objective space-time picture of the actual history of a physical system. This paper suggests how the conceptual foundations of quantum mechanics can be reformulated, without changing the mathematical content of the theory or its detailed agreement with experiment and without introducing any hidden variables, in order to provide an objective, covariant, Lagrangian description of reality which is deterministic and time-symmetric on the microscopic scale. The basis of this description can be expressed either as an action functional or as a summation over Feynman diagrams or paths. The probability laws associated with the quantum-mechanical measurement process, and the asymmetry in time of the principles of macroscopic causality and of the laws of statistical mechanics, are interpreted as consequences of the particular boundary conditions that apply to the actual universe. The objective interpretation does not include the observer and the measurement process among the fundamental concepts of the theory, but it does not entail a revision of the ideas of determinism and of time, since in a Lagrangian theory both initial and final boundary conditions on the action functional are required. (author)

  17. Interpretable Categorization of Heterogeneous Time Series Data

    Science.gov (United States)

    Lee, Ritchie; Kochenderfer, Mykel J.; Mengshoel, Ole J.; Silbermann, Joshua

    2017-01-01

    We analyze data from simulated aircraft encounters to validate and inform the development of a prototype aircraft collision avoidance system. The high-dimensional and heterogeneous time series dataset is analyzed to discover properties of near mid-air collisions (NMACs) and categorize the NMAC encounters. Domain experts use these properties to better organize and understand NMAC occurrences. Existing solutions either are not capable of handling high-dimensional and heterogeneous time series datasets or do not provide explanations that are interpretable by a domain expert. The latter is critical to the acceptance and deployment of safety-critical systems. To address this gap, we propose grammar-based decision trees along with a learning algorithm. Our approach extends decision trees with a grammar framework for classifying heterogeneous time series data. A context-free grammar is used to derive decision expressions that are interpretable, application-specific, and support heterogeneous data types. In addition to classification, we show how grammar-based decision trees can also be used for categorization, which is a combination of clustering and generating interpretable explanations for each cluster. We apply grammar-based decision trees to a simulated aircraft encounter dataset and evaluate the performance of four variants of our learning algorithm. The best algorithm is used to analyze and categorize near mid-air collisions in the aircraft encounter dataset. We describe each discovered category in detail and discuss its relevance to aircraft collision avoidance.

  18. Data analysis and interpretation for environmental surveillance

    International Nuclear Information System (INIS)

    1992-06-01

    The Data Analysis and Interpretation for Environmental Surveillance Conference was held in Lexington, Kentucky, February 5--7, 1990. The conference was sponsored by what is now the Office of Environmental Compliance and Documentation, Oak Ridge National Laboratory. Participants included technical professionals from all Martin Marietta Energy Systems facilities, Westinghouse Materials Company of Ohio, Pacific Northwest Laboratory, and several technical support contractors. Presentations at the conference ranged the full spectrum of issues that effect the analysis and interpretation of environmental data. Topics included tracking systems for samples and schedules associated with ongoing programs; coalescing data from a variety of sources and pedigrees into integrated data bases; methods for evaluating the quality of environmental data through empirical estimates of parameters such as charge balance, pH, and specific conductance; statistical applications to the interpretation of environmental information; and uses of environmental information in risk and dose assessments. Hearing about and discussing this wide variety of topics provided an opportunity to capture the subtlety of each discipline and to appreciate the continuity that is required among the disciplines in order to perform high-quality environmental information analysis

  19. Truth, Representation and Interpretation: The Popper Case

    Directory of Open Access Journals (Sweden)

    Gerard Stan

    2009-06-01

    Full Text Available The aim of this study is to determine several points of reference regarding the way in which Karl Popper built up his philosophical discourse. I locate two specific ways in which Popper interpreted and used ideas belonging to other philosophers. Thus I distinguish in Popper between a projective hermeneutics (where the author uses a thesis that forms a part of his own philosophy in order to reconstruct and understand the ideas of another philosopher and anideological hermeneutics (where he uses a statement expressing an interest of the community whereof he is a member in order to interpret and reconstruct the text of another philosopher. In so doing I also highlight the considerable asymmetry between a representationalist hermeneutics, and a projective and, respectively, an ideological one. Whereas in the first case the interpreter wishes to unveil a truth about the philosophical text, in the other two he israther expressing a desire to talk about himself, his own beliefs and convictions, or about the beliefs of his community of reference.

  20. On the Interpretation of Top Partners Searches

    CERN Document Server

    Matsedonskyi, Oleksii; Wulzer, Andrea

    2014-01-01

    Relatively light Top Partners are unmistakable signatures of reasonably Natural Composite Higgs models and as such they are worth searching for at the LHC. Their phenomenology is characterized by a certain amount of model-dependence, which makes the interpretation of Top Partner experimental searches not completely straightforward especially if one is willing to take also single production into account. We describe a model-independent strategy by which the interpretation is provided on the parameter space of a Simplified Model that captures the relevant features of all the explicit constructions. The Simplified Model limits are easy to interpret within explicit models, in a way that requires no recasting and no knowledge of the experimental details of the analyses. We illustrate the method by concrete examples, among which the searches for a charge 5/3 Partner in same-sign dileptons and the searches for a charge 2/3 singlet. In each case we perform a theory recasting of the available 8 TeV Run-1 results and a...

  1. Identification of different geologic units using fuzzy constrained resistivity tomography

    Science.gov (United States)

    Singh, Anand; Sharma, S. P.

    2018-01-01

    Different geophysical inversion strategies are utilized as a component of an interpretation process that tries to separate geologic units based on the resistivity distribution. In the present study, we present the results of separating different geologic units using fuzzy constrained resistivity tomography. This was accomplished using fuzzy c means, a clustering procedure to improve the 2D resistivity image and geologic separation within the iterative minimization through inversion. First, we developed a Matlab-based inversion technique to obtain a reliable resistivity image using different geophysical data sets (electrical resistivity and electromagnetic data). Following this, the recovered resistivity model was converted into a fuzzy constrained resistivity model by assigning the highest probability value of each model cell to the cluster utilizing fuzzy c means clustering procedure during the iterative process. The efficacy of the algorithm is demonstrated using three synthetic plane wave electromagnetic data sets and one electrical resistivity field dataset. The presented approach shows improvement on the conventional inversion approach to differentiate between different geologic units if the correct number of geologic units will be identified. Further, fuzzy constrained resistivity tomography was performed to examine the augmentation of uranium mineralization in the Beldih open cast mine as a case study. We also compared geologic units identified by fuzzy constrained resistivity tomography with geologic units interpreted from the borehole information.

  2. [Do different interpretative methods used for evaluation of checkerboard synergy test affect the results?].

    Science.gov (United States)

    Ozseven, Ayşe Gül; Sesli Çetin, Emel; Ozseven, Levent

    2012-07-01

    In recent years, owing to the presence of multi-drug resistant nosocomial bacteria, combination therapies are more frequently applied. Thus there is more need to investigate the in vitro activity of drug combinations against multi-drug resistant bacteria. Checkerboard synergy testing is among the most widely used standard technique to determine the activity of antibiotic combinations. It is based on microdilution susceptibility testing of antibiotic combinations. Although this test has a standardised procedure, there are many different methods for interpreting the results. In many previous studies carried out with multi-drug resistant bacteria, different rates of synergy have been reported with various antibiotic combinations using checkerboard technique. These differences might be attributed to the different features of the strains. However, different synergy rates detected by checkerboard method have also been reported in other studies using the same drug combinations and same types of bacteria. It was thought that these differences in synergy rates might be due to the different methods of interpretation of synergy test results. In recent years, multi-drug resistant Acinetobacter baumannii has been the most commonly encountered nosocomial pathogen especially in intensive-care units. For this reason, multidrug resistant A.baumannii has been the subject of a considerable amount of research about antimicrobial combinations. In the present study, the in vitro activities of frequently preferred combinations in A.baumannii infections like imipenem plus ampicillin/sulbactam, and meropenem plus ampicillin/sulbactam were tested by checkerboard synergy method against 34 multi-drug resistant A.baumannii isolates. Minimum inhibitory concentration (MIC) values for imipenem, meropenem and ampicillin/sulbactam were determined by the broth microdilution method. Subsequently the activity of two different combinations were tested in the dilution range of 4 x MIC and 0.03 x MIC in

  3. Electrical resistivity measurements to predict abrasion resistance

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 31; Issue 2. Electrical resistivity measurements to predict abrasion resistance of rock aggregates ... It was seen that correlation coefficients were increased for the rock classes. In addition ...

  4. Persistence, resistance, resonance

    Science.gov (United States)

    Tsadka, Maayan

    Sound cannot travel in a vacuum, physically or socially. The ways in which sound operates are a result of acoustic properties, and the ways by which it is considered to be music are a result of social constructions. Therefore, music is always political, regardless of its content: the way it is performed and composed; the choice of instrumentation, notation, tuning; the medium of its distribution; its inherent hierarchy and power dynamics, and more. My compositional praxis makes me less interested in defining a relationship between music and politics than I am in erasing---or at least blurring---the borders between them. In this paper I discuss the aesthetics of resonance and echo in their metaphorical, physical, social, and musical manifestations. Also discussed is a political aesthetic of resonance, manifested through protest chants. I transcribe and analyze common protest chants from around the world, categorizing and unifying them as universal crowd-mobilizing rhythms. These ideas are explored musically in three pieces. Sumud: Rhetoric of Resistance in Three Movements, for two pianos and two percussion players, is a musical interpretation of the political/social concept of sumud, an Arabic word that literally means "steadfastness" and represents Palestinian non-violent resistance. The piece is based on common protest rhythms and uses the acoustic properties inherent to the instruments. The second piece, Three Piano Studies, extends some of the musical ideas and techniques used in Sumud, and explores the acoustic properties and resonance of the piano. The final set of pieces is part of my Critical Mess Music Project. These are site-specific musical works that attempt to blur the boundaries between audience, performers and composer, in part by including people without traditional musical training in the process of music making. These pieces use the natural structure and resonance of an environment, in this case, locations on the UCSC campus, and offer an active

  5. The Policy Discourse of Networking and Its Effect on School Autonomy: A Foucauldian Interpretation

    Science.gov (United States)

    Mifsud, Denise

    2016-01-01

    Policy discourse officially operates to distinctly influence public perception in an irrevocable and normalising manner. In a Maltese educational scenario of gradual decentralisation and increased accountability, I explore the "effects" of both the global and the local policy discourse of networks and networking on the practising…

  6. Efficacy and safety of dabigatran compared with warfarin at different levels of international normalised ratio control for stroke prevention in atrial fibrillation: an analysis of the RE-LY trial.

    Science.gov (United States)

    Wallentin, Lars; Yusuf, Salim; Ezekowitz, Michael D; Alings, Marco; Flather, Marcus; Franzosi, Maria Grazia; Pais, Prem; Dans, Antonio; Eikelboom, John; Oldgren, Jonas; Pogue, Janice; Reilly, Paul A; Yang, Sean; Connolly, Stuart J

    2010-09-18

    Effectiveness and safety of warfarin is associated with the time in therapeutic range (TTR) with an international normalised ratio (INR) of 2·0-3·0. In the Randomised Evaluation of Long-term Anticoagulation Therapy (RE-LY) trial, dabigatran versus warfarin reduced both stroke and haemorrhage. We aimed to investigate the primary and secondary outcomes of the RE-LY trial in relation to each centre's mean TTR (cTTR) in the warfarin population. In the RE-LY trial, 18 113 patients at 951 sites were randomly assigned to 110 mg or 150 mg dabigatran twice daily versus warfarin dose adjusted to INR 2·0-3·0. Median follow-up was 2·0 years. For 18 024 patients at 906 sites, the cTTR was estimated by averaging TTR for individual warfarin-treated patients calculated by the Rosendaal method. We compared the outcomes of RE-LY across the three treatment groups within four groups defined by the quartiles of cTTR. RE-LY is registered with ClinicalTrials.gov, number NCT00262600. The quartiles of cTTR for patients in the warfarin group were: less than 57·1%, 57·1-65·5%, 65·5-72·6%, and greater than 72·6%. There were no significant interactions between cTTR and prevention of stroke and systemic embolism with either 110 mg dabigatran (interaction p=0·89) or 150 mg dabigatran (interaction p=0·20) versus warfarin. Neither were any significant interactions recorded with cTTR with regards to intracranial bleeding with 110 mg dabigatran (interaction p=0·71) or 150 mg dabigatran (interaction p=0·89) versus warfarin. There was a significant interaction between cTTR and major bleeding when comparing 150 mg dabigatran with warfarin (interaction p=0·03), with less bleeding events at lower cTTR but similar events at higher cTTR, whereas rates of major bleeding were lower with 110 mg dabigatran than with warfarin irrespective of cTTR. There were significant interactions between cTTR and effects of both 110 mg and 150 mg dabigatran versus warfarin on the composite of all

  7. Animation of Antimicrobial Resistance

    Medline Plus

    Full Text Available ... Animal & Veterinary Safety & Health Antimicrobial Resistance Animation of Antimicrobial Resistance Share Tweet Linkedin Pin it More sharing options ... CVM) produced a nine-minute animation explaining how antimicrobial resistance both emerges and proliferates among bacteria. Over time, ...

  8. Combating Antibiotic Resistance

    Science.gov (United States)

    ... Bacteria Phasing Out Certain Antibiotic Use in Farm Animals FDA: Cutting-Edge Technology Sheds Light on Antibiotic Resistance For More Information Antibiotics and Antibiotic Resistance Antimicrobial Resistance Information for Consumers and Health Professionals CDC: ...

  9. Hydraulic resistance of biofilms

    KAUST Repository

    Dreszer, C.; Vrouwenvelder, Johannes S.; Paulitsch-Fuchs, Astrid H.; Zwijnenburg, Arie; Kruithof, Joop C.; Flemming, Hans Curt

    2013-01-01

    resistance is very low compared to the expected biofilm resistance and, thus, biofilm resistance can be determined accurately. Transmembrane pressure drop was monitored. As biofilm parameters, thickness, total cell number, TOC, and extracellular polymeric

  10. Animation of Antimicrobial Resistance

    Medline Plus

    Full Text Available ... Veterinary Safety & Health Antimicrobial Resistance Animation of Antimicrobial Resistance Share Tweet Linkedin Pin it More sharing options ... produced a nine-minute animation explaining how antimicrobial resistance both emerges and proliferates among bacteria. Over time, ...

  11. HIV Resistance Testing

    Science.gov (United States)

    ... 14, 2016 Select a Language: Fact Sheet 126 HIV Resistance Testing WHAT IS RESISTANCE? HOW DOES RESISTANCE ... ARVs. If you miss doses of your medications, HIV will multiply more easily. More mutations will occur. ...

  12. Animation of Antimicrobial Resistance

    Medline Plus

    Full Text Available ... Animal & Veterinary Safety & Health Antimicrobial Resistance Animation of Antimicrobial Resistance Share Tweet Linkedin Pin it More sharing ... CVM) produced a nine-minute animation explaining how antimicrobial resistance both emerges and proliferates among bacteria. Over ...

  13. Problems Faced by Court Interpreters in Botswana | Miyanda ...

    African Journals Online (AJOL)

    Journal Home > Vol 19 (2009) > ... The problems established include lack of training for interpreters, the absence of a job description and guidelines for interpreters, long hours of work, lack of a forum for interpreters to share ideas on their job, lack ... other staff, and lack of equipment such as microphones during interpreting.

  14. The Loud, Clear, and Transporting Voice of Oral Interpretation.

    Science.gov (United States)

    Vartabedian, Robert A.

    This essay examines the art of oral interpretation from a "vocal" perspective--that is, it focuses on the crucial nature of vocal dimensions in oral interpretation. Moreover, the essay argues for an interpreter's hierarchy of vocal needs (modeled after Abraham Maslow's 1970 theory). The interpreter's hierarchy of vocal needs involves…

  15. Three Interpretations of the Matrix Equation Ax = b

    Science.gov (United States)

    Larson, Christine; Zandieh, Michelle

    2013-01-01

    Many of the central ideas in an introductory undergraduate linear algebra course are closely tied to a set of interpretations of the matrix equation Ax = b (A is a matrix, x and b are vectors): linear combination interpretations, systems interpretations, and transformation interpretations. We consider graphic and symbolic representations for each,…

  16. Lineament interpretation. Short review and methodology

    Energy Technology Data Exchange (ETDEWEB)

    Tiren, Sven (GEOSIGMA AB (Sweden))

    2010-11-15

    The ground comprises the solid and continuous surface of the Earth. The crystalline crust, i.e. bedrock, is exposed or covered with sediments and vegetation. The morphology of the ground surface is influenced by a combination of tectonometamorphic- magmatic processes (building up) and denudation/erosion processes (tearing down). Landforms are related to these processes and the character of the bedrock (lithologies and structures), and the distribution of soil or other unconsolidated, superficial material. By using remote-sensing techniques applied for structural analysis of the ground surface, it is possible to map features in the terrain that are related to bedrock structures provided that the topography of the bedrock surface is not totally concealed below a cover of soil or other loose material. Even though the sedimentary cover is relatively thick it may be distorted and the ground surface displaced by late faulting in the basement rock. Studies of the relation between structures in the bedrock and the topography started more than 150 years ago. Hobbs (1903, 1912) introduced the fundamental concept of 'lineaments' and described them as 'significant lines in the Earth's face' and later he concluded that they are 'lines in the landscape which reveal the hidden architecture of the basement'. When airborne geophysical measurements started approximately fifty years ago such data were used to compliment the topographical interpretation of basement structures. Source data for studies of lineaments consist of information on the topography (e.g. topographical maps, aerial photos, elevation data, multi-spectral sensing, laser, radar and thermography) and geophysical data (e.g. airborne geophysical data comprising magnetic, electromagnetic, radiation measurements, and gravimetric measurements). The outcome of a lineament study depends on the terrain in the investigated area, the source data, the approach and systematic performance in the

  17. Lineament interpretation. Short review and methodology

    International Nuclear Information System (INIS)

    Tiren, Sven

    2010-11-01

    The ground comprises the solid and continuous surface of the Earth. The crystalline crust, i.e. bedrock, is exposed or covered with sediments and vegetation. The morphology of the ground surface is influenced by a combination of tectonometamorphic- magmatic processes (building up) and denudation/erosion processes (tearing down). Landforms are related to these processes and the character of the bedrock (lithologies and structures), and the distribution of soil or other unconsolidated, superficial material. By using remote-sensing techniques applied for structural analysis of the ground surface, it is possible to map features in the terrain that are related to bedrock structures provided that the topography of the bedrock surface is not totally concealed below a cover of soil or other loose material. Even though the sedimentary cover is relatively thick it may be distorted and the ground surface displaced by late faulting in the basement rock. Studies of the relation between structures in the bedrock and the topography started more than 150 years ago. Hobbs (1903, 1912) introduced the fundamental concept of 'lineaments' and described them as 'significant lines in the Earth's face' and later he concluded that they are 'lines in the landscape which reveal the hidden architecture of the basement'. When airborne geophysical measurements started approximately fifty years ago such data were used to compliment the topographical interpretation of basement structures. Source data for studies of lineaments consist of information on the topography (e.g. topographical maps, aerial photos, elevation data, multi-spectral sensing, laser, radar and thermography) and geophysical data (e.g. airborne geophysical data comprising magnetic, electromagnetic, radiation measurements, and gravimetric measurements). The outcome of a lineament study depends on the terrain in the investigated area, the source data, the approach and systematic performance in the interpretation, and the skill of

  18. Barak’s Purposive Interpretation in Law as a Pattern of Constitutional Interpretative Fidelity

    Directory of Open Access Journals (Sweden)

    Marinković Tanasije

    2016-12-01

    Full Text Available Political jurisprudence points out that constitutional court judges sometimes act like political actors, and that their decisions are a function of strategic and ideological as much as legal considerations. Consequently, the proper role of the courts, notably in exercising their review of constitutionality, has been one of the most debated issues in modern political and legal theory. Part of the controversy is also how to measure the interpretative fidelity of judges to the constitutional texts, or conversely, the level of their political engagement. This paper argues for the reconsideration of Aharon Barak’s Purposive Interpretation in Law in that light. Barak’s work was intended to provide, in the first place, judges and other lawyers with a sort of judicial philosophy – a holistic system of legal reasoning, applying both to the interpretation of will, contract, statute and constitution. Nevertheless, these conventions of legal reasoning, modified and readapted, could well be used also as heuristic tools by the academics in measuring the interpretative fidelity of judges to various sources of law. Accordingly, this paper clings closely to the presentation of Barak’s precepts for the purposive interpretation of constitutions, by focusing on the notions of subjective and objective purpose in interpreting constitutions, and how the potential conflicts between these purposes are resolved.

  19. Induced resistance: an enhancement of basal resistance?

    NARCIS (Netherlands)

    Vos, M. de; Robben, C.; Pelt, J.A. van; Loon, L.C. van; Pieterse, C.M.J.

    2002-01-01

    Upon primary pathogen attack, plants activate resistance mechanisms at the site of infection. Besides this so-called basal resistance, plants have also the ability to enhance their defensive capacity against future pathogen attack. There are at least two types of biologically induced resistance.

  20. Animation of Antimicrobial Resistance

    Science.gov (United States)

    ... Animal & Veterinary Cosmetics Tobacco Products Animal & Veterinary Home Animal & Veterinary Safety & Health Antimicrobial Resistance Animation of Antimicrobial Resistance Share Tweet Linkedin Pin ...

  1. Animation of Antimicrobial Resistance

    Medline Plus

    Full Text Available ... Animal & Veterinary Cosmetics Tobacco Products Animal & Veterinary Home Animal & Veterinary Safety & Health Antimicrobial Resistance Animation of Antimicrobial Resistance Share Tweet Linkedin Pin ...

  2. Animation of Antimicrobial Resistance

    Medline Plus

    Full Text Available ... More in Antimicrobial Resistance National Antimicrobial Resistance Monitoring System ... If you need help accessing information in different file formats, see Instructions for Downloading ...

  3. The effect of scale on the interpretation of geochemical anomalies

    Science.gov (United States)

    Theobald, P.K.; Eppinger, R.G.; Turner, R.L.; Shiquan, S.

    1991-01-01

    The purpose of geochemical surveys changes with scale. Regional surveys identify areas where mineral deposits are most likely to occur, whereas intermediate surveys identify and prioritize specific targets. At detailed scales specific deposit models may be applied and deposits delineated. The interpretation of regional geochemical surveys must take into account scale-dependent difference in the nature and objectives of this type of survey. Overinterpretation of regional data should be resisted, as should recommendations to restrict intermediate or detailed follow-up surveys to the search for specific deposit types or to a too limited suite of elements. Regional surveys identify metallogenic provinces within which a variety of deposit types and metals are most likely to be found. At intermediate scale, these regional provinces often dissipate into discrete clusters of anomalous areas. At detailed scale, individual anomalous areas reflect local conditions of mineralization and may seem unrelated to each other. Four examples from arid environments illustrate the dramatic change in patterns of anomalies between regional and more detailed surveys. On the Arabian Shield, a broad regional anomaly reflects the distribution of highly differentiated anorogenic granites. A particularly prominent part of the regional anomaly includes, in addition to the usual elements related to the granites, the assemblage of Mo, W and Sn. Initial interpretation suggested potential for granite-related, stockwork Mo deposits. Detailed work identified three separate sources for the anomaly: a metal-rich granite, a silicified and stockwork-veined area with scheelite and molybdenite, and scheelite/powellite concentrations in skarn deposits adjacent to a ring-dike complex. Regional geochemical, geophysical and remote-sensing data in the Sonoran Desert, Mexico, define a series of linear features interpreted to reflect fundamental, northeast-trending fractures in the crust that served as the prime

  4. Multifaceted Interpretation of Colon Cancer Stem Cells.

    Science.gov (United States)

    Hatano, Yuichiro; Fukuda, Shinya; Hisamatsu, Kenji; Hirata, Akihiro; Hara, Akira; Tomita, Hiroyuki

    2017-07-05

    Colon cancer is one of the leading causes of cancer-related deaths worldwide, despite recent advances in clinical oncology. Accumulating evidence sheds light on the existence of cancer stem cells and their role in conferring therapeutic resistance. Cancer stem cells are a minor fraction of cancer cells, which enable tumor heterogeneity and initiate tumor formation. In addition, these cells are resistant to various cytotoxic factors. Therefore, elimination of cancer stem cells is difficult but essential to cure the malignant foci completely. Herein, we review the recent evidence for intestinal stem cells and colon cancer stem cells, methods to detect the tumor-initiating cells, and clinical significance of cancer stem cell markers. We also describe the emerging problems of cancer stem cell theory, including bidirectional conversion and intertumoral heterogeneity of stem cell phenotype.

  5. Combination and interpretation of observables in Cosmology

    Directory of Open Access Journals (Sweden)

    Virey Jean-Marc

    2010-04-01

    Full Text Available The standard cosmological model has deep theoretical foundations but need the introduction of two major unknown components, dark matter and dark energy, to be in agreement with various observations. Dark matter describes a non-relativistic collisionless fluid of (non baryonic matter which amount to 25% of the total density of the universe. Dark energy is a new kind of fluid not of matter type, representing 70% of the total density which should explain the recent acceleration of the expansion of the universe. Alternatively, one can reject this idea of adding one or two new components but argue that the equations used to make the interpretation should be modified consmological scales. Instead of dark matter one can invoke a failure of Newton's laws. Instead of dark energy, two approaches are proposed : general relativity (in term of the Einstein equation should be modified, or the cosmological principle which fixes the metric used for cosmology should be abandonned. One of the main objective of the community is to find the path of the relevant interpretations thanks to the next generation of experiments which should provide large statistics of observationnal data. Unfortunately, cosmological in formations are difficult to pin down directly fromt he measurements, and it is mandatory to combine the various observables to get the cosmological parameters. This is not problematic from the statistical point of view, but assumptions and approximations made for the analysis may bias our interprettion of the data. Consequently, a strong attention should be paied to the statistical methods used to make parameters estimation and for model testing. After a review of the basics of cosmology where the cosmological parameters are introduced, we discuss the various cosmological probes and their associated observables used to extract cosmological informations. We present the results obtained from several statistical analyses combining data of diferent nature but

  6. Chest radiograph interpretation by medical students

    International Nuclear Information System (INIS)

    Jeffrey, D.R.; Goddard, P.R.; Callaway, M.P.; Greenwood, R.

    2003-01-01

    AIM: To assess the ability of final year medical students to interpret conventional chest radiographs. MATERIALS AND METHODS: Ten conventional chest radiographs were selected from a teaching hospital radiology department library that were good radiological examples of common conditions. All were conditions that a medical student should be expected to recognize by the end of their training. One normal radiograph was included. The radiographs were shown to 52 final year medical students who were asked to describe their findings. RESULTS: The median score achieved was 12.5 out of 20 (range 6-18). There was no difference between the median scores of male and female students (12.5 and 12.3, respectively, p=0.82) but male students were more likely to be certain of their answers than female students (median certainty scores 23.0 and 14.0, respectively). The overall degree of certainty was low. On no radiograph were more than 25% of students definite about their answer. Students had received little formal radiology teaching (2-42 h, median 21) and few expressed an interest in radiology as a career. Only two (3.8%) students thought they were good at interpreting chest radiographs, 17 (32.7%) thought they were bad or awful. CONCLUSION: Medical students reaching the end of their training do not perform well at interpreting simple chest radiographs. They lack confidence and have received little formal radiological tuition. Perhaps as a result, few are interested in radiology as a career, which is a matter for concern in view of the current shortage of radiologists in the UK

  7. NAIL SAMPLING TECHNIQUE AND ITS INTERPRETATION

    Directory of Open Access Journals (Sweden)

    TZAR MN

    2011-01-01

    Full Text Available The clinical suspicion of onychomyosis based on appearance of the nails, requires culture for confirmation. This is because treatment requires prolonged use of systemic agents which may cause side effects. One of the common problems encountered is improper nail sampling technique which results in loss of essential information. The unfamiliar terminologies used in reporting culture results may intimidate physicians resulting in misinterpretation and hamper treatment decision. This article provides a simple guide on nail sampling technique and the interpretation of culture results.

  8. Constituent gluon interpretation of glueballs and gluelumps

    International Nuclear Information System (INIS)

    Boulanger, N.; Buisseret, F.; Mathieu, V.; Semay, C.

    2008-01-01

    Arguments are given that support the interpretation of the lattice QCD glueball and gluelump spectra in terms of bound states of massless constituent gluons with helicity 1. In this scheme, we show that the mass hierarchy of the currently known gluelumps and glueballs is mainly due to the number of constituent gluons and can be understood within a simple flux tube model. It is also argued that the lattice QCD 0 +- glueball should be seen as a four-gluon bound state. We finally predict the mass of the 0 - state, not yet computed in lattice QCD. (orig.)

  9. Statistics and Data Interpretation for Social Work

    CERN Document Server

    Rosenthal, James

    2011-01-01

    "Without question, this text will be the most authoritative source of information on statistics in the human services. From my point of view, it is a definitive work that combines a rigorous pedagogy with a down to earth (commonsense) exploration of the complex and difficult issues in data analysis (statistics) and interpretation. I welcome its publication.". -Praise for the First Edition. Written by a social worker for social work students, this is a nuts and bolts guide to statistics that presents complex calculations and concepts in clear, easy-to-understand language. It includes

  10. Defining Marriage: Classification, Interpretation, and Definitional Disputes

    Directory of Open Access Journals (Sweden)

    Fabrizio Macagno

    2016-09-01

    Full Text Available The classification of a state of affairs under a legal category can be considered as a kind of con- densed decision that can be made explicit, analyzed, and assessed us- ing argumentation schemes. In this paper, the controversial conflict of opinions concerning the nature of “marriage” in Obergefell v. Hodges is analyzed pointing out the dialecti- cal strategies used for addressing the interpretive doubts. The dispute about the same-sex couples’ right to marry hides a much deeper disa- greement not only about what mar- riage is, but more importantly about the dialectical rules for defining it.

  11. How to interpret liver function tests

    Directory of Open Access Journals (Sweden)

    Christina Levick

    2017-05-01

    Full Text Available Careful interpretation of liver function tests within the clinical context can help elucidate the cause and severity of the underlying pathology. Predominantly raised alkaline phosphatase represents the cholestatic pattern of biliary pathology, whilst predominantly raised alanine aminotransferase and aspartate aminotransferase represent the hepatocellular pattern of hepatocellular pathology. The severity of liver dysfunction or biliary obstruction is reflected in the bilirubin level and the degree of liver synthetic function can also be indicated by the albumin level. Beyond the liver function tests, prothrombin time provides another marker of liver synthetic function and a low platelet count suggests portal hypertension.

  12. Static analysis of software the abstract interpretation

    CERN Document Server

    Boulanger, Jean-Louis

    2013-01-01

    The existing literature currently available to students and researchers is very general, covering only the formal techniques of static analysis. This book presents real examples of the formal techniques called ""abstract interpretation"" currently being used in various industrial fields: railway, aeronautics, space, automotive, etc. The purpose of this book is to present students and researchers, in a single book, with the wealth of experience of people who are intrinsically involved in the realization and evaluation of software-based safety critical systems. As the authors are people curr

  13. Advanced oral radiographic interpretations. Vol. 2

    International Nuclear Information System (INIS)

    Bentley, K.C.; Langlais, R.P.

    1981-01-01

    The book will help to interpret X-ray pictures, differential diagnoses are developed, and the resulting unambiguous information is combined in order to arrive at the ultimate diagnosis. 88 cases are presented with their anamneses, symptomes, clinical findings, and laboratory data. In some cases also photographs and histological sections are presented. The case histories, characteristic findings, and X-ray pictures selected are typical of those cases in which diagnosis is difficult. Most X-ray pictures presented in the book are typical of the pertinent diseases. (orig./MG) [de

  14. Algorithmic tools for interpreting vital signs.

    Science.gov (United States)

    Rathbun, Melina C; Ruth-Sahd, Lisa A

    2009-07-01

    Today's complex world of nursing practice challenges nurse educators to develop teaching methods that promote critical thinking skills and foster quick problem solving in the novice nurse. Traditional pedagogies previously used in the classroom and clinical setting are no longer adequate to prepare nursing students for entry into practice. In addition, educators have expressed frustration when encouraging students to apply newly learned theoretical content to direct the care of assigned patients in the clinical setting. This article presents algorithms as an innovative teaching strategy to guide novice student nurses in the interpretation and decision making related to vital sign assessment in an acute care setting.

  15. European Equivalencies in Legal Interpreting and Translation

    DEFF Research Database (Denmark)

    Corsellis, Ann; Hertog, Erik; Martinsen, Bodil

    2002-01-01

    Within Europe there is increasing freedom of movement between countries and increasing inward migration. As a result, equivalent standards of legl interpreting and translation are required to allow reliable communication for judicial cooperation between member states, for criminal and civil matters...... which cross national borders and for the needs of multilingual populations. The European Convention of Human Rights (article 6, paragrph 3) is one of the main planks of relevant legislation. This international, two year project has been funded by the EU Grotius programme to set out what is required...

  16. Re-Interpreting the "Chinese miracle"

    DEFF Research Database (Denmark)

    Feng, Xingyuan; Ljungwall, Christer; Guo, Sujian

    2011-01-01

    The rapid economic development and transformation of Chinese society over the past three decades has, by a large mass of analysts, been called a "Miracle." This paper not only addresses the shortcomings of existing interpretations but also develops a new multi-dimensional framework based on North......'s theory of institutional change and Hayek's theory of institutional evolution to explain China's miraculous growth. Our analysis shows that both Hayekian spontaneous order and Popper's "piecemeal social engineering" played a major role in attaining China's miraculous growth....

  17. Causal interpretation of stochastic differential equations

    DEFF Research Database (Denmark)

    Sokol, Alexander; Hansen, Niels Richard

    2014-01-01

    We give a causal interpretation of stochastic differential equations (SDEs) by defining the postintervention SDE resulting from an intervention in an SDE. We show that under Lipschitz conditions, the solution to the postintervention SDE is equal to a uniform limit in probability of postintervention...... structural equation models based on the Euler scheme of the original SDE, thus relating our definition to mainstream causal concepts. We prove that when the driving noise in the SDE is a Lévy process, the postintervention distribution is identifiable from the generator of the SDE....

  18. De Broglie's causal interpretations of quantum mechanics

    International Nuclear Information System (INIS)

    Ben-Dov, Y.

    1989-01-01

    In this article we trace the history of de Broglie's two causal interpretations of quantum mechanics, namely the double solution and the pilot wave theories, at the two periods in which he developed them: 1924-27 and 1952 onwards. Examining the reasons for which he always preferred the first theory to the second, reasons that are mainly concerned with the question of the physical nature of the quantum wave function, we try to show the continuity and the coherence of his underlying vision

  19. Neutrons and antimony physical measurements and interpretations

    International Nuclear Information System (INIS)

    Smith, A. B.

    2000-01-01

    New experimental information for the elastic and inelastic scattering of ∼ 4--10 MeV neutrons from elemental antimony is presented. The differential measurements are made at ∼ 40 or more scattering angles and at incident neutron-energy intervals of ∼ 0.5 MeV. The present experimental results, those previously reported from this laboratory and as found in the literature are comprehensively interpreted using spherical optical-statistical and dispersive-optical models. Direct vibrational processes via core-excitation, isospin and shell effects are discussed. Antimony models for applications are proposed and compared with global, regional, and specific models reported in the literature

  20. Rational interpretation of the postulates in plasticity

    Directory of Open Access Journals (Sweden)

    Bohua Sun

    2014-01-01

    Full Text Available This article is mainly focussed on revisited of the two well-known postulates of plasticity, i.e., the Drucker and the Il’iushin postulate, and it describes their rational interpretation within the framework of irreversible thermodynamics and using exterior calculus. It shows that the Il’iushin and the Drucker postulate is the integral form and local form of the irreversible thermodynamics of plastic deformation, respectively. The Drucker and Il’iushin postulate is equivalent for both soft and hardening materials.